WorldWideScience

Sample records for native synthetic imaging

  1. Synthetic Aperture Ultrasound Imaging

    DEFF Research Database (Denmark)

    Jensen, Jørgen Arendt; Nikolov, Svetoslav; Gammelmark, Kim Løkke

    2006-01-01

    The paper describes the use of synthetic aperture (SA) imaging in medical ultrasound. SA imaging is a radical break with today's commercial systems, where the image is acquired sequentially one image line at a time. This puts a strict limit on the frame rate and the possibility of acquiring...... a sufficient amount of data for high precision flow estimation. These constrictions can be lifted by employing SA imaging. Here data is acquired simultaneously from all directions over a number of emissions, and the full image can be reconstructed from this data. The talk will demonstrate the many benefits...... of SA imaging. Due to the complete data set, it is possible to have both dynamic transmit and receive focusing to improve contrast and resolution. It is also possible to improve penetration depth by employing codes during ultrasound transmission. Data sets for vector flow imaging can be acquired using...

  2. Synthetic Aperture Compound Imaging

    DEFF Research Database (Denmark)

    Hansen, Jens Munk

    Medical ultrasound imaging is used for many purposes, e.g. for localizing and classifying cysts, lesions, and other processes. Almost any mass is first observed using B-mode imaging and later classified using e.g. color flow, strain, or attenuation imaging. It is therefore important that the B....... The method is investigated using simulations and through measurements using both phased array and convex array transducers. The images all show an improved contrast compared to images without compounding, and by construction, imaging using an improved frame rate is possible. Using a phased array transducer...... and the limiting factor is the amount of memory IO resources available. An equally high demand for memory throughput is found in the computer gaming industry, where a large part of the processing takes place on the graphics processing unit (GPU). Using the GPU, a framework for synthetic aperture imaging...

  3. Transionospheric synthetic aperture imaging

    CERN Document Server

    Gilman, Mikhail; Tsynkov, Semyon

    2017-01-01

    This landmark monograph presents the most recent mathematical developments in the analysis of ionospheric distortions of SAR images and offers innovative new strategies for their mitigation. As a prerequisite to addressing these topics, the book also discusses the radar ambiguity theory as it applies to synthetic aperture imaging and the propagation of radio waves through the ionospheric plasma, including the anisotropic and turbulent cases. In addition, it covers a host of related subjects, such as the mathematical modeling of extended radar targets (as opposed to point-wise targets) and the scattering of radio waves off those targets, as well as the theoretical analysis of the start-stop approximation, which is used routinely in SAR signal processing but often without proper justification. The mathematics in this volume is clean and rigorous – no assumptions are hidden or ambiguously stated. The resulting work is truly interdisciplinary, providing both a comprehensive and thorough exposition of the field,...

  4. Tissue Harmonic Synthetic Aperture Imaging

    DEFF Research Database (Denmark)

    Rasmussen, Joachim

    The main purpose of this PhD project is to develop an ultrasonic method for tissue harmonic synthetic aperture imaging. The motivation is to advance the field of synthetic aperture imaging in ultrasound, which has shown great potentials in the clinic. Suggestions for synthetic aperture tissue...... system complexity compared to conventional synthetic aperture techniques. In this project, SASB is sought combined with a pulse inversion technique for 2nd harmonic tissue harmonic imaging. The advantages in tissue harmonic imaging (THI) are expected to further improve the image quality of SASB...... harmonic techniques have been made, but none of these methods have so far been applicable for in-vivo imaging. The basis of this project is a synthetic aperture technique known as synthetic aperture sequential beamforming (SASB). The technique utilizes a two step beamforming approach to drastically reduce...

  5. Imaging with Synthetic Aperture Radar

    CERN Document Server

    Massonnet, Didier

    2008-01-01

    Describing a field that has been transformed by the recent availability of data from a new generation of space and airborne systems, the authors offer a synthetic geometrical approach to the description of synthetic aperture radar, one that addresses physicists, radar specialists, as well as experts in image processing.  

  6. Optimizing Synthetic Aperture Compound Imaging

    DEFF Research Database (Denmark)

    Hansen, Jens Munk; Jensen, Jørgen Arendt

    2012-01-01

    Spatial compound images are constructed from synthetic aperture data acquired using a linear phased-array transducer. Compound images of wires, tissue, and cysts are created using a method, which allows both transmit and receive compounding without any loss in temporal resolution. Similarly to co...

  7. Synthetic Aperture Vector Flow Imaging

    DEFF Research Database (Denmark)

    Oddershede, Niels

    2008-01-01

    of the thesis considers a method for estimating the two-dimensional velocity vector within the image plane. This method, called synthetic aperture vector flow imaging, is first shortly reviewed. The main contribution of this work is partly an analysis of the method with respect to focusing effects, motion...... estimation. The method can be used for increasing the frame rate of color flow maps or alternatively for a new imaging modality entitled quadroplex imaging, featuring a color flow map and two independent spectrograms at a high frame rate. The second is an alternative method for ultrasonic vector velocity...

  8. Imaging synthetic aperture radar

    Science.gov (United States)

    Burns, Bryan L.; Cordaro, J. Thomas

    1997-01-01

    A linear-FM SAR imaging radar method and apparatus to produce a real-time image by first arranging the returned signals into a plurality of subaperture arrays, the columns of each subaperture array having samples of dechirped baseband pulses, and further including a processing of each subaperture array to obtain coarse-resolution in azimuth, then fine-resolution in range, and lastly, to combine the processed subapertures to obtain the final fine-resolution in azimuth. Greater efficiency is achieved because both the transmitted signal and a local oscillator signal mixed with the returned signal can be varied on a pulse-to-pulse basis as a function of radar motion. Moreover, a novel circuit can adjust the sampling location and the A/D sample rate of the combined dechirped baseband signal which greatly reduces processing time and hardware. The processing steps include implementing a window function, stabilizing either a central reference point and/or all other points of a subaperture with respect to doppler frequency and/or range as a function of radar motion, sorting and compressing the signals using a standard fourier transforms. The stabilization of each processing part is accomplished with vector multiplication using waveforms generated as a function of radar motion wherein these waveforms may be synthesized in integrated circuits. Stabilization of range migration as a function of doppler frequency by simple vector multiplication is a particularly useful feature of the invention; as is stabilization of azimuth migration by correcting for spatially varying phase errors prior to the application of an autofocus process.

  9. Fast Parametric Beamformer for Synthetic Aperture Imaging

    DEFF Research Database (Denmark)

    Nikolov, Svetoslav; Jensen, Jørgen Arendt; Tomov, Borislav Gueorguiev

    2008-01-01

    . The implementation of the beamformer is optimized with respect to the architecture of a novel synthetic aperture real-time ultrasound scanner (SARUS), in which 4 channels are processed by the same set of field-programmable gate arrays (FPGA). In synthetic transmit aperture imaging, low-resolution images are formed...

  10. Practical Applications of Synthetic Aperture Imaging

    DEFF Research Database (Denmark)

    Nikolov, Svetoslav Ivanov; Kortbek, Jacob; Jensen, Jørgen Arendt

    2010-01-01

    Synthetic aperture imaging has been a focus of research for almost 3 decades. The research carried out at the Center for Fast Ultrasound Imaging has demonstrated that synthetic aperture focusing not only can be used in-vivo, but that it also yields superior B-mode and blood flow images. In the last......, and multiple angle flash imaging are just a few of the names used to describe the commercial implementations of synthetic aperture focusing. Although they sound like different algorithms, they are the same in their core, as revealed in this paper....

  11. Synthetic Aperture Imaging in Medical Ultrasound

    DEFF Research Database (Denmark)

    Nikolov, Svetoslav; Gammelmark, Kim; Pedersen, Morten

    2004-01-01

    with high precision, and the imaging is easily extended to real-time 3D scanning. This paper presents the work done at the Center for Fast Ultrasound Imaging in the area of SA imaging. Three areas that benefit from SA imaging are described. Firstly a preliminary in-vivo evaluation comparing conventional B......Synthetic Aperture (SA) ultrasound imaging is a relatively new and unexploited imaging technique. The images are perfectly focused both in transmit and receive, and have a better resolution and higher dynamic range than conventional ultrasound images. The blood flow can be estimated from SA images...

  12. Synthetic Imaging Maneuver Optimization (SIMO) Project

    Data.gov (United States)

    National Aeronautics and Space Administration — Aurora Flight Sciences (AFS), in collaboration with the MIT Space Systems Laboratory (MIT-SSL), proposed the Synthetic Imaging Maneuver Optimization (SIMO) program...

  13. High frame rate synthetic aperture duplex imaging

    DEFF Research Database (Denmark)

    Stuart, Matthias Bo; Tomov, Borislav Gueorguiev; Pihl, Michael Johannes

    2013-01-01

    aperture flow imaging as demonstrated in this paper. Synthetic aperture, directional beamforming, and cross-correlation are used to produce B-mode and vector velocity images at high frame rates. The frame rate equals the effective pulse repetition frequency of each imaging mode. Emissions for making the B...

  14. Sequential Beamforming Synthetic Aperture Imaging

    DEFF Research Database (Denmark)

    Kortbek, Jacob; Jensen, Jørgen Arendt; Gammelmark, Kim Løkke

    2013-01-01

    Synthetic aperture sequential beamforming (SASB) is a novel technique which allows to implement synthetic aperture beamforming on a system with a restricted complexity, and without storing RF-data. The objective is to improve lateral resolution and obtain a more depth independent resolution...... and a range independent lateral resolution is obtained. The SASB method has been investigated using simulations in Field II and by off-line processing of data acquired with a commercial scanner. The lateral resolution increases with a decreasing F#. Grating lobes appear if F# 6 2 for a linear array with k-pitch...

  15. Synthetic Aperture Vector Flow Imaging

    DEFF Research Database (Denmark)

    Villagómez Hoyos, Carlos Armando

    The main objective of this project was to continue the development of a synthetic aperture vector flow estimator. This type of estimator is capable of overcoming two of the major limitations in conventional ultrasound systems: 1) the inability to scan large region of interest with high temporal...... resolutions; 2) the lack of capability in detecting flow other than the one along the direction of the beam. Addressing these technical limitations would translate in the clinic as a gain in valuable clinical information and a removal of operator-dependant sources of error, which would improve the diagnosis....... The main contribution of this work was the development of an angle estimator which features high accuracy and low standard deviation over the full 360◦ range. The estimator demonstrated its capability of operating at high frame rates (> 1000 Hz), and simultaneously detecting a large range of flow...

  16. Flame Reconstruction Using Synthetic Aperture Imaging

    CERN Document Server

    Murray, Preston; Tree, Dale; Truscott, Tadd

    2011-01-01

    Flames can be formed by burning methane (CH4). When oxygen is scarce, carbon particles nucleate into solid particles called soot. These particles emit photons, making the flame yellow. Later, methane is pre-mixed with air forming a blue flame; burning more efficiently, providing less soot and light. Imaging flames and knowing their temperature are vital to maximizing efficiency and validating numerical models. Most temperature probes disrupt the flame and create differences leading to an inaccurate measurement of the flame temperature. We seek to image the flame in three dimensions using synthetic aperture imaging. This technique has already successfully measured velocity fields of a vortex ring [1]. Synthetic aperture imaging is a technique that views one scene from multiple cameras set at different angles, allowing some cameras to view objects that are obscured by others. As the resulting images are overlapped different depths of the scene come into and out of focus, known as focal planes, similar to tomogr...

  17. Optimization of Synthetic Aperture Image Quality

    DEFF Research Database (Denmark)

    Moshavegh, Ramin; Jensen, Jonas; Villagómez Hoyos, Carlos Armando

    2016-01-01

    Synthetic Aperture (SA) imaging produces high-quality images and velocity estimates of both slow and fast flow at high frame rates. However, grating lobe artifacts can appear both in transmission and reception. These affect the image quality and the frame rate. Therefore optimization of parameters...... effecting the image quality of SA is of great importance, and this paper proposes an advanced procedure for optimizing the parameters essential for acquiring an optimal image quality, while generating high resolution SA images. Optimization of the image quality is mainly performed based on measures...... such as F-number, number of emissions and the aperture size. They are considered to be the most contributing acquisition factors in the quality of the high resolution images in SA. Therefore, the performance of image quality is quantified in terms of full-width at half maximum (FWHM) and the cystic...

  18. Directional synthetic aperture flow imaging

    DEFF Research Database (Denmark)

    Jensen, Jørgen Arendt; Nikolov, Svetoslav

    2004-01-01

    .36% (0.65 mm/s). Using the same set-up for the purely transverse flow gave a std. of 1.2% (2.1 mm/s). Variation of the different parameters has been done to reveal the sensitivity to number of lines, angle deviations, length of correlation interval, and sampling interval. An in-vivo image of the carotid...

  19. Parametric Beamformer for Synthetic Aperture Ultrasound Imaging

    DEFF Research Database (Denmark)

    Nikolov, Svetoslav; Tomov, Borislav Gueorguiev; Jensen, Jørgen Arendt

    2006-01-01

    . The beamformer consists of a number of identical beamforming blocks, each processing data from several channels and producing part of the image. A number of these blocks can be accommodated in a modern field-programmable gate array device (FPGA), and a whole synthetic aperture system can be implemented using......In this paper a parametric beamformer, which can handle all imaging modalities including synthetic aperture imaging, is presented. The image lines and apodization coefficients are specified parametrically, and the lines can have arbitrary orientation and starting point in 3D coordinates...... several FPGAs. For the current implementation, the input data is sampled at 4 times the center frequency of the excitation pulse and is match-filtered in the frequency domain. In-phase and quadrature data are beamformed with a sub-sample precision of the focusing delays of 1/16th of the sampling period...

  20. Synthetic aperture tissue and flow ultrasound imaging

    DEFF Research Database (Denmark)

    Nikolov, Svetoslav

    them: the use of sparse one- and two-dimensional arrays; the use of multiple elements in transmit to create virtual sources of ultrasound; the use of virtual sources of ultrasound to improve the resolution of the images in the elevation plane; the use of temporal and spatial encoding to increase...... imaging applied to medical ultrasound. It is divided into two major parts: tissue and blood flow imaging. Tissue imaging using synthetic aperture algorithms has been investigated for about two decades, but has not been implemented in medical scanners yet. Among the other reasons, the conventional scanning...

  1. Synthetic Aperture Ladar Imaging and Atmospheric Turbulence

    Science.gov (United States)

    2016-06-09

    to pursue a claim for personal or organizational intellectual property ? Changes in research objectives (if any): None Change in AFOSR Program Manager...T. J. Wright, “Synthetic-aperture imaging laser radar: laboratory demonstration and signal processing,” Appl . Opt., vol. 44, no. 35, pp. 7621–7629

  2. Compound imaging using Synthetic Aperture Sequential Beamformation

    DEFF Research Database (Denmark)

    Jensen, Casper Bo; Jensen, Jonas; Hemmsen, Martin Christian

    2011-01-01

    Synthetic Aperture Sequential Beamforming (SASB) is a technique with low complexity and the ability to yield a more uniform lateral resolution with range. However, the presence of speckle artifacts in ultrasound images degrades the contrast. In conventional imaging speckle is reduced by using...... spatial compounding at the cost of a reduced frame rate. The objective is to apply spatial compounding to SASB and evaluate if the images have a reduced speckle appearance and thereby an improved image quality in terms of contrast compared to ordinary SASB. Using the simulation software Field II, RF data...... detection the five second stage images are added to form the compounded image. Using a ProFocus scanner and the 8804 linear array transducer (BK Medical, Herlev, Denmark) measurements of a phantom containing water filled cysts are obtained to validate the simulation results. The setup is the same...

  3. Tissue Harmonic Synthetic Aperture Ultrasound Imaging

    DEFF Research Database (Denmark)

    Hemmsen, Martin Christian; Rasmussen, Joachim; Jensen, Jørgen Arendt

    2014-01-01

    , and data were recorded with and without pulse inversion for tissue harmonic imaging. Data were acquired using a Sound Technol- ogy 192 element convex array transducer from both a wire phantom and a tissue mimicking phantom to investigate spatial resolution and pen- etration. In-vivo scans were also......Synthetic aperture sequential beamforming (SASB) and tissue har- monic imaging (THI) are combined to improve the image quality of medical ultrasound imaging. The technique is evaluated in a compar- ative study against dynamic receive focusing (DRF). The objective is to investigate if SASB combined...... with THI improves the image qual- ity compared to DRF-THI. The major benet of SASB is a reduced bandwidth between the probe and processing unit. A BK Medical 2202 Ultraview ultrasound scanner was used to acquire beamformed RF data for oine evaluation. The acquisition was made interleaved between methods...

  4. Multistatic synthetic aperture radar image formation.

    Science.gov (United States)

    Krishnan, V; Swoboda, J; Yarman, C E; Yazici, B

    2010-05-01

    In this paper, we consider a multistatic synthetic aperture radar (SAR) imaging scenario where a swarm of airborne antennas, some of which are transmitting, receiving or both, are traversing arbitrary flight trajectories and transmitting arbitrary waveforms without any form of multiplexing. The received signal at each receiving antenna may be interfered by the scattered signal due to multiple transmitters and additive thermal noise at the receiver. In this scenario, standard bistatic SAR image reconstruction algorithms result in artifacts in reconstructed images due to these interferences. In this paper, we use microlocal analysis in a statistical setting to develop a filtered-backprojection (FBP) type analytic image formation method that suppresses artifacts due to interference while preserving the location and orientation of edges of the scene in the reconstructed image. Our FBP-type algorithm exploits the second-order statistics of the target and noise to suppress the artifacts due to interference in a mean-square sense. We present numerical simulations to demonstrate the performance of our multistatic SAR image formation algorithm with the FBP-type bistatic SAR image reconstruction algorithm. While we mainly focus on radar applications, our image formation method is also applicable to other problems arising in fields such as acoustic, geophysical and medical imaging.

  5. Optical Phase Imaging Using Synthetic Aperture Illumination and Phase Retrieval

    CERN Document Server

    Lee, Dennis J

    2016-01-01

    We perform quantitative phase imaging using phase retrieval to implement synthetic aperture imaging. Compared to digital holography, the developed technique is simpler, less expensive, and more stable.

  6. Molecular Imaging in Synthetic Biology, and Synthetic Biology in Molecular Imaging.

    Science.gov (United States)

    Gilad, Assaf A; Shapiro, Mikhail G

    2017-06-01

    Biomedical synthetic biology is an emerging field in which cells are engineered at the genetic level to carry out novel functions with relevance to biomedical and industrial applications. This approach promises new treatments, imaging tools, and diagnostics for diseases ranging from gastrointestinal inflammatory syndromes to cancer, diabetes, and neurodegeneration. As these cellular technologies undergo pre-clinical and clinical development, it is becoming essential to monitor their location and function in vivo, necessitating appropriate molecular imaging strategies, and therefore, we have created an interest group within the World Molecular Imaging Society focusing on synthetic biology and reporter gene technologies. Here, we highlight recent advances in biomedical synthetic biology, including bacterial therapy, immunotherapy, and regenerative medicine. We then discuss emerging molecular imaging approaches to facilitate in vivo applications, focusing on reporter genes for noninvasive modalities such as magnetic resonance, ultrasound, photoacoustic imaging, bioluminescence, and radionuclear imaging. Because reporter genes can be incorporated directly into engineered genetic circuits, they are particularly well suited to imaging synthetic biological constructs, and developing them provides opportunities for creative molecular and genetic engineering.

  7. Dynamic force microscopy imaging of native membranes

    Energy Technology Data Exchange (ETDEWEB)

    Kienberger, Ferry; Stroh, Cordula; Kada, Gerald; Moser, Rosita; Baumgartner, Werner; Pastushenko, Vassili; Rankl, Christian; Schmidt, Ute; Mueller, Harald; Orlova, Elena; LeGrimellec, Christian; Drenckhahn, Detlev; Blaas, Dieter; Hinterdorfer, Peter

    2003-10-15

    We employed magnetic ACmode atomic force microscopy (MACmode AFM) as a novel dynamic force microscopy method to image surfaces of biological membranes in their native environments. The lateral resolution achieved under optimized imaging conditions was in the nanometer range, even when the sample was only weakly attached to the support. Purple membranes (PM) from Halobacterium salinarum were used as a test standard for topographical imaging. The hexagonal arrangement of the bacteriorhodopsin trimers on the cytoplasmic side of PM was resolved with 1.5 nm lateral accuracy, a resolution similar to images obtained in contact and tapping-mode AFM. Human rhinovirus 2 (HRV2) particles were attached to mica surfaces via nonspecific interactions. The capsid structure and 2 nm sized protein loops of HRV2 were routinely obtained without any displacement of the virus. Globular and filamentous structures on living and fixed endothelial cells were observed with a resolution of 5-20 nm. These examples show that MACmode AFM is a favorable method in studying the topography of soft and weakly attached biological samples with high resolution under physiological conditions.

  8. Brain imaging with synthetic MR in children: clinical quality assessment

    Energy Technology Data Exchange (ETDEWEB)

    Betts, Aaron M.; Serai, Suraj [Cincinnati Children' s Hospital Medical Center, Department of Radiology, Cincinnati, OH (United States); Leach, James L.; Jones, Blaise V. [Cincinnati Children' s Hospital Medical Center, Department of Radiology, Cincinnati, OH (United States); University of Cincinnati College of Medicine, Cincinnati, OH (United States); Zhang, Bin [Cincinnati Children' s Hospital Medical Center, Biostatistics and Epidemiology, Cincinnati, OH (United States)

    2016-10-15

    Synthetic magnetic resonance imaging is a quantitative imaging technique that measures inherent T1-relaxation, T2-relaxation, and proton density. These inherent tissue properties allow synthesis of various imaging sequences from a single acquisition. Clinical use of synthetic MR imaging has been described in adult populations. However, use of synthetic MR imaging has not been previously reported in children. The purpose of this study is to report our assessment of diagnostic image quality using synthetic MR imaging in children. Synthetic MR acquisition was obtained in a sample of children undergoing brain MR imaging. Image quality assessments were performed on conventional and synthetic T1-weighted, T2-weighted, and FLAIR images. Standardized linear measurements were performed on conventional and synthetic T2 images. Estimates of patient age based upon myelination patterns were also performed. Conventional and synthetic MR images were evaluated on 30 children. Using a 4-point assessment scale, conventional imaging performed better than synthetic imaging for T1-weighted, T2-weighted, and FLAIR images. When the assessment was simplified to a dichotomized scale, the conventional and synthetic T1-weighted and T2-weighted images performed similarly. However, the superiority of conventional FLAIR images persisted in the dichotomized assessment. There were no statistically significant differences between linear measurements made on T2-weighted images. Estimates of patient age based upon pattern of myelination were also similar between conventional and synthetic techniques. Synthetic MR imaging may be acceptable for clinical use in children. However, users should be aware of current limitations that could impact clinical utility in the software version used in this study. (orig.)

  9. Advanced methods in synthetic aperture radar imaging

    Science.gov (United States)

    Kragh, Thomas

    2012-02-01

    For over 50 years our world has been mapped and measured with synthetic aperture radar (SAR). A SAR system operates by transmitting a series of wideband radio-frequency pulses towards the ground and recording the resulting backscattered electromagnetic waves as the system travels along some one-dimensional trajectory. By coherently processing the recorded backscatter over this extended aperture, one can form a high-resolution 2D intensity map of the ground reflectivity, which we call a SAR image. The trajectory, or synthetic aperture, is achieved by mounting the radar on an aircraft, spacecraft, or even on the roof of a car traveling down the road, and allows for a diverse set of applications and measurement techniques for remote sensing applications. It is quite remarkable that the sub-centimeter positioning precision and sub-nanosecond timing precision required to make this work properly can in fact be achieved under such real-world, often turbulent, vibrationally intensive conditions. Although the basic principles behind SAR imaging and interferometry have been known for decades, in recent years an explosion of data exploitation techniques enabled by ever-faster computational horsepower have enabled some remarkable advances. Although SAR images are often viewed as simple intensity maps of ground reflectivity, SAR is also an exquisitely sensitive coherent imaging modality with a wealth of information buried within the phase information in the image. Some of the examples featured in this presentation will include: (1) Interferometric SAR, where by comparing the difference in phase between two SAR images one can measure subtle changes in ground topography at the wavelength scale. (2) Change detection, in which carefully geolocated images formed from two different passes are compared. (3) Multi-pass 3D SAR tomography, where multiple trajectories can be used to form 3D images. (4) Moving Target Indication (MTI), in which Doppler effects allow one to detect and

  10. Tissue harmonic synthetic aperture ultrasound imaging.

    Science.gov (United States)

    Hemmsen, Martin Christian; Rasmussen, Joachim Hee; Jensen, Jørgen Arendt

    2014-10-01

    Synthetic aperture sequential beamforming (SASB) and tissue harmonic imaging (THI) are combined to improve the image quality of medical ultrasound imaging. The technique is evaluated in a comparative study against dynamic receive focusing (DRF). The objective is to investigate if SASB combined with THI improves the image quality compared to DRF-THI. The major benefit of SASB is a reduced bandwidth between the probe and processing unit. A BK Medical 2202 Ultraview ultrasound scanner was used to acquire beamformed RF data for offline evaluation. The acquisition was made interleaved between methods, and data were recorded with and without pulse inversion for tissue harmonic imaging. Data were acquired using a Sound Technology 192 element convex array transducer from both a wire phantom and a tissue mimicking phantom to investigate spatial resolution and penetration. In vivo scans were also performed for a visual comparison. The spatial resolution for SASB-THI is on average 19% better than DRI-THI, and the investigation of penetration showed equally good signal-to-noise ratio. In vivo B-mode scans were made and compared. The comparison showed that SASB-THI reduces the artifact and noise interference and improves image contrast and spatial resolution.

  11. Triangulation using synthetic aperture radar images

    Science.gov (United States)

    Wu, Sherman S. C.; Howington-Kraus, Annie E.

    1991-01-01

    For the extraction of topographic information about Venus from stereoradar images obtained from the Magellan Mission, a Synthetic Aperture Radar (SAR) compilation system was developed on analytical stereoplotters. The system software was extensively tested by using stereoradar images from various spacecraft and airborne radar systems, including Seasat, SIR-B, ERIM XCL, and STAR-1. Stereomodeling from radar images was proven feasible, and development is on a correct approach. During testing, the software was enhanced and modified to obtain more flexibility and better precision. Triangulation software for establishing control points by using SAR images was also developed through a joint effort with the Defense Mapping Agency. The SAR triangulation system comprises four main programs, TRIDATA, MODDATA, TRISAR, and SHEAR. The first two programs are used to sort and update the data; the third program, the main one, performs iterative statistical adjustment; and the fourth program analyzes the results. Also, input are flight data and data from the Global Positioning System and Inertial System (navigation information). The SAR triangulation system was tested with six strips of STAR-1 radar images on a VAX-750 computer. Each strip contains images of 10 minutes flight time (equivalent to a ground distance of 73.5 km); the images cover a ground width of 22.5 km. All images were collected from the same side. With an input of 44 primary control points, 441 ground control points were produced. The adjustment process converged after eight iterations. With a 6-m/pixel resolution of the radar images, the triangulation adjustment has an average standard elevation error of 81 m. Development of Magellan radargrammetry will be continued to convert both SAR compilation and triangulation systems into digital form.

  12. Synthetic-Aperture Silhouette Imaging (SASI)

    Science.gov (United States)

    Paxman, R.

    2016-09-01

    The problem of ground-based fine-resolution imaging of geosynchronous satellites continues to be an important unsolved space-surveillance problem. We are investigating a passive-illumination approach that is radically different from amplitude, intensity, or heterodyne interferometry approaches. The approach, called Synthetic-Aperture Silhouette Imaging (SASI), produces a fine-resolution image of the satellite silhouette. When plane-wave radiation emanating from a bright star is occluded by a GEO satellite, then the light is diffracted and a moving diffraction pattern (shadow) is cast on the surface of the earth. With prior knowledge of the satellite orbit and star location, the track of the moving shadow can be predicted with high precision. A linear array of inexpensive hobby telescopes can be deployed roughly perpendicular to the shadow track to collect a time history of the star intensity as the shadow passes by. A phase-retrieval algorithm, using the strong constraint that the occlusion of the satellite is a binary-valued silhouette, allows us to retrieve the missing phase and reconstruct a fine-resolution image of the silhouette. Silhouettes are highly informative, providing diagnostic information about deployment of antennas and solar panels, enabling satellite pose estimation, and revealing the presence and orientation of neighboring satellites in rendezvous and proximity operations.

  13. Oceanic eddies in synthetic aperture radar images

    Indian Academy of Sciences (India)

    Andrei Yu Ivanov; Anna I Ginzburg

    2002-09-01

    Continuous observations since 1991 by using synthetic aperture radar (SAR) on board the Almaz-1, ERS-1/2, JERS-1, and RADARSAT satellites support the well-known fact that oceanic eddies are distributed worldwide in the ocean. The paper is devoted to an evaluation of the potential of SAR for detection of eddies and vortical motions in the ocean. The classification of typical vortical features in the ocean detected in remote sensing images (visible, infrared, and SAR) is presented as well as available information on their spatial and temporal scales. Examples of the Almaz-1 and ERS-1/2 SAR images showing different eddy types, such as rings, spiral eddies of the open ocean, eddies behind islands and in bays, spin-off eddies and mushroom-like structures (vortex dipoles) are given and discussed. It is shown that a common feature for most of the eddies detected in the SAR images is a broad spectrum of spatial scales, spiral shape and shear nature. It is concluded that the spaceborne SARs give valuable information on ocean eddies, especially in combination with visible and infrared satellite data.

  14. A SPECT imager with synthetic collimation

    Science.gov (United States)

    Havelin, Ronan J.; Miller, Brian W.; Barrett, Harrison H.; Furenlid, Lars R.; Murphy, J. M.; Foley, Mark J.

    2013-09-01

    This work outlines the development of a multi-pinhole SPECT system designed to produce a synthetic-collimator image of a small field of view. The focused multi-pinhole collimator was constructed using rapid-prototyping and casting techniques. The collimator projects the field of view through forty-six pinholes when the detector is adjacent to the collimator. The detector is then moved further from the collimator to increase the magnification of the system. The amount of pinhole-projection overlap increases with the system magnification. There is no rotation in the system; a single tomographic angle is used in each system configuration. The maximum-likelihood expectation-maximization (MLEM) algorithm is implemented on graphics processing units to reconstruct the object in the field of view. Iterative reconstruction algorithms, such as MLEM, require an accurate model of the system response. For each system magnification, a sparsely-sampled system response is measured by translating a point source through a grid encompassing the field of view. The pinhole projections are individually identified and associated with their respective apertures. A 2D elliptical Gaussian model is applied to the pinhole projections on the detector. These coefficients are associated with the object-space location of the point source, and a finely-sampled system matrix is interpolated. Simulations with a hot-rod phantom demonstrate the efficacy of combining low-resolution non-multiplexed data with high-resolution multiplexed data to produce high-resolution reconstructions.

  15. Autonomous ship classification using synthetic and real color images

    Science.gov (United States)

    Kumlu, Deniz; Jenkins, B. Keith

    2013-03-01

    This work classifies color images of ships attained using cameras mounted on ships and in harbors. Our data-sets contain 9 different types of ship with 18 different perspectives for our training set, development set and testing set. The training data-set contains modeled synthetic images; development and testing data-sets contain real images. The database of real images was gathered from the internet, and 3D models for synthetic images were imported from Google 3D Warehouse. A key goal in this work is to use synthetic images to increase overall classification accuracy. We present a novel approach for autonomous segmentation and feature extraction for this problem. Support vector machine is used for multi-class classification. This work reports three experimental results for multi-class ship classification problem. First experiment trains on a synthetic image data-set and tests on a real image data-set, and obtained accuracy is 87.8%. Second experiment trains on a real image data-set and tests on a separate real image data-set, and obtained accuracy is 87.8%. Last experiment trains on real + synthetic image data-sets (combined data-set) and tests on a separate real image data-set, and obtained accuracy is 93.3%.

  16. Preliminary comparison of 3D synthetic aperture imaging with Explososcan

    Science.gov (United States)

    Rasmussen, Morten Fischer; Hansen, Jens Munk; Férin, Guillaume; Dufait, Rémi; Jensen, Jørgen Arendt

    2012-03-01

    Explososcan is the 'gold standard' for real-time 3D medical ultrasound imaging. In this paper, 3D synthetic aperture imaging is compared to Explososcan by simulation of 3D point spread functions. The simulations mimic a 32×32 element prototype transducer. The transducer mimicked is a dense matrix phased array with a pitch of 300 μm, made by Vermon. For both imaging techniques, 289 emissions are used to image a volume spanning 60° in both the azimuth and elevation direction and 150mm in depth. This results for both techniques in a frame rate of 18 Hz. The implemented synthetic aperture technique reduces the number of transmit channels from 1024 to 256, compared to Explososcan. In terms of FWHM performance, was Explososcan and synthetic aperture found to perform similar. At 90mm depth is Explososcan's FWHM performance 7% better than that of synthetic aperture. Synthetic aperture improved the cystic resolution, which expresses the ability to detect anechoic cysts in a uniform scattering media, at all depths except at Explososcan's focus point. Synthetic aperture reduced the cyst radius, R20dB, at 90mm depth by 48%. Synthetic aperture imaging was shown to reduce the number of transmit channels by four and still, generally, improve the imaging quality.

  17. A framework for creating realistic synthetic fluorescence microscopy image sequences

    CSIR Research Space (South Africa)

    Mabaso, M

    2016-02-01

    Full Text Available of the 9th International Joint Conference on Biomedical Engineering Systems and Technologies, Rome, Italy. 21-23 February, 2016 A Framework for Creating Realistic Synthetic Fluorescence Microscopy Image Sequences Matsilele Mabaso1, Daniel Withey1...

  18. In Vivo Real Time Volumetric Synthetic Aperture Ultrasound Imaging

    DEFF Research Database (Denmark)

    Bouzari, Hamed; Rasmussen, Morten Fischer; Brandt, Andreas Hjelm;

    2015-01-01

    Synthetic aperture (SA) imaging can be used to achieve real-time volumetric ultrasound imaging using 2-D array transducers. The sensitivity of SA imaging is improved by maximizing the acoustic output, but one must consider the limitations of an ultrasound system, both technical and biological...

  19. Apparatus and method for velocity estimation in synthetic aperture imaging

    DEFF Research Database (Denmark)

    2003-01-01

    The invention relates to an apparatus for flow estimation using synthetic aperture imaging. The method uses a Synthetic Transmit Aperture, but unlike previous approaches a new frame is created after every pulse emission. In receive mode parallel beam forming is implemented. The beam formed RF data......). The update signals are used in the velocity estimation processor (8) to correlate the individual measurements to obtain the displacement between high-resolution images and thereby determine the velocity....

  20. Synthetic aperture integration (SAI) algorithm for SAR imaging

    Science.gov (United States)

    Chambers, David H; Mast, Jeffrey E; Paglieroni, David W; Beer, N. Reginald

    2013-07-09

    A method and system for detecting the presence of subsurface objects within a medium is provided. In some embodiments, the imaging and detection system operates in a multistatic mode to collect radar return signals generated by an array of transceiver antenna pairs that is positioned across the surface and that travels down the surface. The imaging and detection system pre-processes the return signal to suppress certain undesirable effects. The imaging and detection system then generates synthetic aperture radar images from real aperture radar images generated from the pre-processed return signal. The imaging and detection system then post-processes the synthetic aperture radar images to improve detection of subsurface objects. The imaging and detection system identifies peaks in the energy levels of the post-processed image frame, which indicates the presence of a subsurface object.

  1. Synthetic SAR Image Generation using Sensor, Terrain and Target Models

    DEFF Research Database (Denmark)

    Kusk, Anders; Abulaitijiang, Adili; Dall, Jørgen

    2016-01-01

    A tool to generate synthetic SAR images of objects set on a clutter background is described. The purpose is to generate images for training Automatic Target Recognition and Identification algorithms. The tool employs a commercial electromagnetic simulation program to calculate radar cross sections...... of the object using a CAD-model. The raw measurements are input to a SAR system and terrain model, which models thermal noise, terrain clutter, and SAR focusing to produce synthetic SAR images. Examples of SAR images at 0.3m and 0.1m resolution, and a comparison with real SAR imagery from the MSTAR dataset...

  2. Inverse synthetic aperture radar imaging principles, algorithms and applications

    CERN Document Server

    Chen , Victor C

    2014-01-01

    Inverse Synthetic Aperture Radar Imaging: Principles, Algorithms and Applications is based on the latest research on ISAR imaging of moving targets and non-cooperative target recognition (NCTR). With a focus on the advances and applications, this book will provide readers with a working knowledge on various algorithms of ISAR imaging of targets and implementation with MATLAB. These MATLAB algorithms will prove useful in order to visualize and manipulate some simulated ISAR images.

  3. Proton Radiography Imager:Generates Synthetic Proton Radiographs

    Energy Technology Data Exchange (ETDEWEB)

    2017-09-12

    ProRad is a computer program that is used to generate synthetic images of proton (or other charged particles) radiographs. The proton radiographs arc images that arc obtained by sending energetic protons (or electrons or positrons, for example) through 11 plasma where electric and/or magnetic fields alter the particles trajectory, Dnd the variations me imaged on RC film, image plate, or equivalent

  4. A Microwave Imaging and Enhancement Technique from Noisy Synthetic Data

    CERN Document Server

    Kundu, Anjan Kumar; Sanyal, Sugata

    2010-01-01

    An inverse iterative algorithm for microwave imaging based on moment method solution is presented here. The iterative scheme has been developed on constrained optimization technique and is certain to converge. Different mesh size for the model has been used here to overcome the Inverse Crime. The synthetic data at the receivers is contaminated with different percentage of noise. The ill-posedness of the problem is solved by Levenberg-Marquardt method. The algorithm is applied to synthetic data and the reconstructed image is then further enhanced through the Image enhancement technique

  5. Multiregion level-set partitioning of synthetic aperture radar images.

    Science.gov (United States)

    Ben Ayed, Ismail; Mitiche, Amar; Belhadj, Ziad

    2005-05-01

    The purpose of this study is to investigate Synthetic Aperture Radar (SAR) image segmentation into a given but arbitrary number of gamma homogeneous regions via active contours and level sets. The segmentation of SAR images is a difficult problem due to the presence of speckle which can be modeled as strong, multiplicative noise. The proposed algorithm consists of evolving simple closed planar curves within an explicit correspondence between the interiors of curves and regions of segmentation to minimize a criterion containing a term of conformity of data to a speckle model of noise and a term of regularization. Results are shown on both synthetic and real images.

  6. Preliminary comparison of 3D synthetic aperture imaging with Explososcan

    DEFF Research Database (Denmark)

    Rasmussen, Morten Fischer; Hansen, Jens Munk; Ferin, Guillaume

    2012-01-01

    Explososcan is the 'gold standard' for real-time 3D medical ultrasound imaging. In this paper, 3D synthetic aperture imaging is compared to Explososcan by simulation of 3D point spread functions. The simulations mimic a 32x32 element prototype transducer. The transducer mimicked is a dense matrix...

  7. Synthetic SAR Image Generation using Sensor, Terrain and Target Models

    DEFF Research Database (Denmark)

    Kusk, Anders; Abulaitijiang, Adili; Dall, Jørgen

    2016-01-01

    A tool to generate synthetic SAR images of objects set on a clutter background is described. The purpose is to generate images for training Automatic Target Recognition and Identification algorithms. The tool employs a commercial electromagnetic simulation program to calculate radar cross section...

  8. Images and Stereotypes of the Native American.

    Science.gov (United States)

    Chilcoat, George W.

    1988-01-01

    Reviews how the popular stereotypes of American Indians have changed since the colonization of North America. Once seen as noble savages by European settlers, the popular stereotypes changed to become less and less positive as colonization advanced. Urges teachers to vigorously challenge the stereotypes and negative images. (JDH)

  9. Synthetic Imaging Maneuver Optimization (SIMO) Project

    Data.gov (United States)

    National Aeronautics and Space Administration — Space-based interferometry missions have the potential to revolutionize imaging and astrometry, providing observations of unprecedented accuracy. Realizing the full...

  10. Sacajawea and Her Sisters: Images and Native Women.

    Science.gov (United States)

    Valaskakis, Gail Guthrie

    1999-01-01

    Historicized images of First Nations women ("princesses" and "squaws") and related narratives are deeply entrenched in North American popular culture. These appropriated, commodified representations circulate in the politics of difference and influence the identities of Native women. But their mothers' and grandmothers'…

  11. Range-instantaneous Doppler imaging of inverse synthetic aperture sonar

    Institute of Scientific and Technical Information of China (English)

    XU Jia; JIANG Xingzhou; TANG Jingsong

    2003-01-01

    Because the existing range-Doppler algorithm in inverse synthetic aperture sonar (ISAS) is based on target model of uniform motion, it may be invalidated for maneuvering targets due to the time-varying changes of both individual scatter′s Doppler and imaging projection plane. To resolve the problem, a new range-instantaneous Doppler imaging method is proposed for imaging maneuvering targets based on time-frequency analysis. The proposed approach is verified using real underwater acoustic data.

  12. Passive Synthetic Aperture Radar Imaging Using Commercial OFDM Communication Networks

    Science.gov (United States)

    2012-09-13

    PASSIVE SYNTHETIC APERTURE RADAR IMAGING USING COMMERCIAL OFDM COMMUNICATION NETWORKS DISSERTATION José R. Gutiérrez del Arroyo, Major, USAF AFIT...IMAGING USING COMMERCIAL OFDM COMMUNICATION NETWORKS DISSERTATION Presented to the Faculty Graduate School of Engineering and Management Air Force...DISTRIBUTION IS UNLIMITED. AFIT/ DEE/ E G/12-10 PASSIVE SY THETIC APERTURE RADAR IMAGING USI G COMMERCIAL OFDM COMMUNICATIO r ETWORKS Jose R. Gutierrez

  13. In-vivo examples of synthetic aperture vector flow imaging

    DEFF Research Database (Denmark)

    Oddershede, Niels; Hansen, Kristoffer Lindskov; Nielsen, Michael Bachmann;

    2007-01-01

    would be needed. Synthetic aperture vector flow imaging could potentially provide this. The purpose of this paper is to test the synthetic aperture vector flow imaging method on challenging in-vivo data. Two synthetic aperture in-vivo data sets are acquired using a commercial linear array transducer...... and our RASMUS experimental ultrasound scanner. The first data set covers the femoral artery and the confluence of the femoral and saphenous vein of a healthy 26-year-old male volunteer. The second shows the carotid bifurcation of a healthy 32-year-old male volunteer. Both 2 second long data sets...... are processed, and movies of full vector flow images are generated. This paper presents still frames from different time instances of these movies. The movie from the femoral data tracks the accelerating velocity in the femoral artery during systole and a backwards flow at the end of the systole. A complex flow...

  14. Synthetic Aperture Sequential Beamformation applied to medical imaging

    DEFF Research Database (Denmark)

    Hemmsen, Martin Christian; Hansen, Jens Munk; Jensen, Jørgen Arendt

    2012-01-01

    Synthetic Aperture Sequential Beamforming (SASB) is applied to medical ultrasound imaging using a multi element convex array transducer. The main motivation for SASB is to apply synthetic aperture techniques without the need for storing RF-data for a number of elements and hereby devise a system...... with a reduced system complexity. Using a 192 element, 3.5 MHz, λ-pitch transducer, it is demonstrated using tissue-phantom and wire-phantom measurements, how the speckle size and the detail resolution is improved compared to conventional imaging....

  15. Velocity estimation using synthetic aperture imaging

    DEFF Research Database (Denmark)

    Nikolov, Svetoslav; Jensen, Jørgen Arendt

    2001-01-01

    In a previous paper we have demonstrated that the velocity can be estimated for a plug flow using recursive ultrasound imaging [1]. The approach involved the estimation of the velocity at every emission and using the estimates for motion compensation. An error in the estimates, however, would lead...... to an error in the compensation further increasing the error in the estimates. In this paper the approach is further developed such that no motion compensation is necessary. In recursive ultrasound imaging a new high resolution image is created after every emission. The velocity was estimated by cross...... and significantly improves the velocity estimates. The approach is verified using simulations with the program Field II and measurements on a blood-mimicking phantom. The estimates from the simulations have a bias of -3.5% and a mean standard deviation less than 2.0% for a parabolic velocity profile. The estimates...

  16. In-vivo evaluation of convex array synthetic aperture imaging

    DEFF Research Database (Denmark)

    Pedersen, Morten Høgholm; Gammelmark, Kim Løkke; Jensen, Jørgen Arendt

    2007-01-01

    This paper presents an in-vivo study of synthetic transmit aperture (STA) imaging in comparison to conventional imaging, evaluating whether STA imaging is feasible in-vivo, and whether the image quality obtained is comparable to traditional scanned imaging in terms of penetration depth, spatial...... resolution, contrast resolution, and artifacts. Acquisition was performed using our research scanner RASMUS and a 5.5 MHz convex array transducer. STA imaging was acquired using circular wave emulation by 33-element subapertures and a 20 us linear FM signal as excitation pulse. For conventional imaging a 64...... element aperture was used in transmit and receive with a 1.5 cycle sinusoid excitation pulse. Conventional and STA images were acquired interleaved ensuring that the exact same anatomical location was scanned. Image sequences were recorded in real-time and processed off-line. Seven male volunteers were...

  17. Spaceborne bistatic synthetic aperture imaging radar

    Science.gov (United States)

    Elachi, C.; Goldstein, R.; Held, D.

    1981-01-01

    The properties of two configurations for a spaceborne bistatic SAR are examined and compared with the properties of a monostatic SAR. The two bistatic configurations considered are a system consisting of an orbiting spaceborne transmitter and a ground receiver and a system consisting of a transmitter on a geostationary satellite and a receiver or receivers on an airborne platform. The properties discussed or analyzed include imaging coordinate system, azimuth and range resolution, azimuth and range ambiguities, and swath width.

  18. Motion compensated beamforming in synthetic aperture vector flow imaging

    DEFF Research Database (Denmark)

    Oddershede, Niels; Jensen, Jørgen Arendt

    2006-01-01

    . Here the SNR is -10 dB compared to the stationary scatterer. A 2D motion compensation method for synthetic aperture vector flow imaging is proposed, where the former vector velocity estimate is used for compensating the beamforming of new data. This method is tested on data from an experimental flow......In synthetic aperture imaging the beamformed data from a number of emissions are summed to create dynamic focusing in transmit. This makes the method susceptible to motion, which is especially the case for the synthetic aperture flow estimation method, where large movements are expected......) of the beamformed response from the scatterer at all velocities is compared to that of a stationary scatterer. For lateral movement, the SNR drops almost linearly with velocity to -4 dB at I m/s, while for axial movement the SNR drop is largest, when the scatterer moves a quarter of a wavelength between emissions...

  19. Fourier beamformation of multistatic synthetic aperture ultrasound imaging

    DEFF Research Database (Denmark)

    Moghimirad, Elahe; Villagómez Hoyos, Carlos Armando; Mahloojifar, Ali

    2015-01-01

    A new Fourier beamformation (FB) algorithm is presented for multistatic synthetic aperture ultrasound imaging. It can reduce the number of computations by a factor of 20 compared to conventional Delay-and-Sum (DAS) beamformers. The concept is based on the wavenumber algorithm from radar and sonar...

  20. Imaging blood’s velocity using synthetic aperture ultrasound

    DEFF Research Database (Denmark)

    Jensen, Jørgen Arendt; Li, Ye

    2012-01-01

    The blood velocity vector can be estimated using synthetic aperture techniques in medical ultrasound by using short emission sequences. The whole image region is insonified and the flow can be tracked in all directions continuously. This is a major advantage compared to commercial systems, since...

  1. Synthetic Aperture Sonar Imaging via One-Way Wave Equations

    CERN Document Server

    Huynh, Quyen

    2009-01-01

    We develop an efficient algorithm for Synthetic Aperture Sonar imaging based on the one-way wave equations. The algorithm utilizes the operator-splitting method to integrate the one-way wave equations. The well-posedness of the one-way wave equations and the proposed algorithm is shown. A computational result against real field data is reported and the resulting image is enhanced by the BV-like regularization.

  2. Performance of Synthetic Aperture Compounding for in-vivo imaging

    DEFF Research Database (Denmark)

    Hansen, Jens Munk; Jensen, Jørgen Arendt

    2011-01-01

    A method for synthetic aperture compounding (SAC) is applied to data from water tank measurements, data from a tissue-mimicking phantom, and clinical data from the abdomen of a healthy 27 year old male. Further, using this method compounding can be obtained without any loss in temporal resolution......, contrast ratios (CR) are computed between regions in the portal and hepatic veins and the surrounding tissue. An average improvement of 15% is obtained when comparing SAC images to SA images without compounding........ The water tank measurements reveal an improved detail resolution of 45% when comparing SAC to conventional compounding and an improvement of 22%, when comparing to synthetic aperture (SA) imaging. The cystic resolution at 12 dB is improved by 50% and 12% when comparing SAC to conventional compounding and SA...... imaging respectively. The tissue phantom measurements show a 3.2 dB improvement of the normalized information density (NID) when comparing images formed using SAC to conventional compound images and an improvement of 2 dB for a comparison between SAC imaging and SA imaging. For the clinical images...

  3. Single-epitope recognition imaging of native chromatin

    Directory of Open Access Journals (Sweden)

    Wang Hongda

    2008-12-01

    Full Text Available Abstract Background Direct visualization of chromatin has the potential to provide important insights into epigenetic processes. In particular, atomic force microscopy (AFM can visualize single nucleosomes under physiological ionic conditions. However, AFM has mostly been applied to chromatin that has been reconstituted in vitro, and its potential as a tool for the dissection of native nucleosomes has not been explored. Recently we applied AFM to native Drosophila chromatin containing the centromere-specific histone 3 (CenH3, showing that it is greatly enriched in smaller particles. Taken together with biochemical analyses of CenH3 nucleosomes, we propose that centromeric nucleosomes are hemisomes, with one turn of DNA wrapped around a particle consisting of one molecule each of centromere-specific CenH3, H4, H2A and H2B. Results Here we apply a recognition mode of AFM imaging to directly identify CenH3 within histone core particles released from native centromeric chromatin. More than 90% of these particles were found to be tetrameric in height. The specificity of recognition was confirmed by blocking with a CenH3 peptide, and the strength of the interaction was quantified by force measurements. These results imply that the particles imaged by AFM are indeed mature CenH3-containing hemisomes. Conclusion Efficient and highly specific recognition of CenH3 in histone core particles isolated from native centromeric chromatin demonstrates that tetramers are the predominant form of centromeric nucleosomes in mature tetramers. Our findings provide proof of principle that this approach can yield insights into chromatin biology using direct and rapid detection of native nucleosomes in physiological salt concentrations.

  4. Minimum description length synthetic aperture radar image segmentation.

    Science.gov (United States)

    Galland, Frédéric; Bertaux, Nicolas; Réfrégier, Philippe

    2003-01-01

    We present a new minimum description length (MDL) approach based on a deformable partition--a polygonal grid--for automatic segmentation of a speckled image composed of several homogeneous regions. The image segmentation thus consists in the estimation of the polygonal grid, or, more precisely, its number of regions, its number of nodes and the location of its nodes. These estimations are performed by minimizing a unique MDL criterion which takes into account the probabilistic properties of speckle fluctuations and a measure of the stochastic complexity of the polygonal grid. This approach then leads to a global MDL criterion without an undetermined parameter since no other regularization term than the stochastic complexity of the polygonal grid is necessary and noise parameters can be estimated with maximum likelihood-like approaches. The performance of this technique is illustrated on synthetic and real synthetic aperture radar images of agricultural regions and the influence of different terms of the model is analyzed.

  5. Implementation of Synthetic Aperture Imaging in Medical Ultrasound

    DEFF Research Database (Denmark)

    Jensen, Jørgen Arendt; Kortbek, Jacob; Nikolov, Svetoslav

    2010-01-01

    The main advantage of medical ultrasound imaging is its real time capability, which makes it possible to visualize dynamic structures in the human body. Real time synthetic aperture imaging puts very high demands on the hardware, which currently cannot be met. A method for reducing the number...... of calculations and still retain the many advantages of SA imaging is described. It consists of a dual stage beamformer, where the first can be a simple fixed focus analog beamformer and the second an ordinary digital ultrasound beamformer. The performance and constrictions of the approach is described....

  6. Duplex synthetic aperture imaging with tissue motion compensation

    DEFF Research Database (Denmark)

    Gammelmark, Kim; Jensen, Jørgen Arendt

    2003-01-01

    This paper investigates a method for tissue motion estimation and compensation in synthetic transmits aperture imaging. The approach finds the tissue velocity and the direction of the motion at very tissue region by cross-correlating high resolution lines beamformed along multiple directions...... at each image points. Compensation is applied in the beamformer by tracking the image points using the velocity and angle estimates from the closest estimation point. Simulation results using Field II show nearly perfect motion compensation with no appreciable difference in contrast resolution after...

  7. Passive synthetic aperture radar imaging of ground moving targets

    Science.gov (United States)

    Wacks, Steven; Yazici, Birsen

    2012-05-01

    In this paper we present a method for imaging ground moving targets using passive synthetic aperture radar. A passive radar imaging system uses small, mobile receivers that do not radiate any energy. For these reasons, passive imaging systems result in signicant cost, manufacturing, and stealth advantages. The received signals are obtained by multiple airborne receivers collecting scattered waves due to illuminating sources of opportunity such as commercial television, radio, and cell phone towers. We describe a novel forward model and a corresponding ltered-backprojection type image reconstruction method combined with entropy optimization. Our method determines the location and velocity of multiple targets moving at dierent velocities. Furthermore, it can accommodate arbitrary imaging geometries. we present numerical simulations to verify the imaging method.

  8. Sparse synthetic aperture radar imaging with optimized azimuthal aperture

    Institute of Scientific and Technical Information of China (English)

    ZENG Cao; WANG MinHang; LIAO GuiSheng; ZHU ShengQi

    2012-01-01

    To counter the problem of acquiring and processing huge amounts of data for synthetic aperture radar (SAR) using traditional sampling techniques,a method for sparse SAR imaging with an optimized azimuthal aperture is presented.The equivalence of an azimuthal match filter and synthetic array beamforming is shown so that optimization of the azimuthal sparse aperture can be converted to optimization of synthetic array beamforming.The azimuthal sparse aperture,which is composed of a middle aperture and symmetrical bilateral apertures,can be obtained by optimization algorithms (density weighting and simulated annealing algorithms,respectively).Furthermore,sparse imaging of spectrum analysis SAR based on the optimized sparse aperture is achieved by padding zeros at null samplings and using a non-uniform Taylor window. Compared with traditional sampling,this method has the advantages of reducing the amount of sampling and alleviating the computational burden with acceptable image quality.Unlike periodic sparse sampling,the proposed method exhibits no image ghosts.The results obtained from airborne measurements demonstrate the effectiveness and superiority of the proposed method.

  9. In-vivo synthetic aperture flow imaging in medical ultrasound

    DEFF Research Database (Denmark)

    Nikolov, Svetoslav; Jensen, Jørgen Arendt

    2003-01-01

    .2% and a mean relative bias of 3.4% using 24 pulse emissions at a flow angle of 45 degrees. The 24 emissions can be used for making a full-color flow map image. An in-vivo image of How in the carotid artery for a 29-year-old male also is presented. The full image is acquired using 24 emissions.......A new method for acquiring flow images using synthetic aperture techniques in medical ultrasound is presented. The new approach makes it possible to have a continuous acquisition of flow data throughout the whole image simultaneously, and this can significantly improve blood velocity estimation....... Any type of filter can be used for discrimination between tissue and blood flow without initialization, and the number of lines used for velocity estimation is limited only by the nonstationarity of the flow. The new approach is investigated through both simulations and measurements. A flow rig...

  10. In Vivo Real Time Volumetric Synthetic Aperture Ultrasound Imaging

    DEFF Research Database (Denmark)

    Bouzari, Hamed; Rasmussen, Morten Fischer; Brandt, Andreas Hjelm

    2015-01-01

    . This paper investigates the in vivo applicability and sensitivity of volumetric SA imaging. Utilizing the transmit events to generate a set of virtual point sources, a frame rate of 25 Hz for a 90° x 90° field-of-view was achieved. Data were obtained using a 3.5 MHz 32 x 32 elements 2-D phased array......Synthetic aperture (SA) imaging can be used to achieve real-time volumetric ultrasound imaging using 2-D array transducers. The sensitivity of SA imaging is improved by maximizing the acoustic output, but one must consider the limitations of an ultrasound system, both technical and biological...... transducer connected to the experimental scanner (SARUS). Proper scaling is applied to the excitation signal such that intensity levels are in compliance with the U.S. Food and Drug Administration regulations for in vivo ultrasound imaging. The measured Mechanical Index and spatial-peak- temporal...

  11. Logarithmic Laplacian Prior Based Bayesian Inverse Synthetic Aperture Radar Imaging.

    Science.gov (United States)

    Zhang, Shuanghui; Liu, Yongxiang; Li, Xiang; Bi, Guoan

    2016-04-28

    This paper presents a novel Inverse Synthetic Aperture Radar Imaging (ISAR) algorithm based on a new sparse prior, known as the logarithmic Laplacian prior. The newly proposed logarithmic Laplacian prior has a narrower main lobe with higher tail values than the Laplacian prior, which helps to achieve performance improvement on sparse representation. The logarithmic Laplacian prior is used for ISAR imaging within the Bayesian framework to achieve better focused radar image. In the proposed method of ISAR imaging, the phase errors are jointly estimated based on the minimum entropy criterion to accomplish autofocusing. The maximum a posterior (MAP) estimation and the maximum likelihood estimation (MLE) are utilized to estimate the model parameters to avoid manually tuning process. Additionally, the fast Fourier Transform (FFT) and Hadamard product are used to minimize the required computational efficiency. Experimental results based on both simulated and measured data validate that the proposed algorithm outperforms the traditional sparse ISAR imaging algorithms in terms of resolution improvement and noise suppression.

  12. Optimum synthetic-aperture imaging of extended astronomical objects.

    Science.gov (United States)

    van der Avoort, Casper; Pereira, Silvania F; Braat, Joseph J M; den Herder, Jan-Willem

    2007-04-01

    In optical aperture-synthesis imaging of stellar objects, different beam combination strategies are used and proposed. Coaxial Michelson interferometers are very common and a homothetic multiaxial interferometer is recently realized in the Large Binocular Telescope. Laboratory experiments have demonstrated the working principles of two new approaches: densified pupil imaging and wide field-of-view (FOV) coaxial imaging using a staircase-shaped mirror. We develop a common mathematical formulation for direct comparison of the resolution and noise sensitivity of these four telescope configurations for combining beams from multiple apertures for interferometric synthetic aperture, wide-FOV imaging. Singular value decomposition techniques are used to compare the techniques and observe their distinct signal-to-noise ratio behaviors. We conclude that for a certain chosen stellar object, clear differences in performance of the imagers are identifiable.

  13. Real-time synthetic aperture imaging: opportunities and challenges

    DEFF Research Database (Denmark)

    Nikolov, Svetoslav; Tomov, Borislav Gueorguiev; Jensen, Jørgen Arendt

    2006-01-01

    in the region of interest it is possible to beamform the signals along a desired path, thus, improving the estimation of blood flow. The transmission of coded excitations makes it possible to achieve higher contrast and larger penetration depth compared to "conventional" scanners. This paper presents......Synthetic aperture (SA) ultrasound imaging has not been introduced in commercial scanners mainly due to the computational cost associated with the hardware implementation of this imaging modality. SA imaging redefines the term beamformed line. Since the acquired information comes from all points...... in 3D. This parametric description makes it possible to quickly change the image geometry during scanning, thus enabling adaptive imaging and precise flow estimation. The paper addresses problems such as large bandwidth and computational load and gives the solutions that have been adopted...

  14. New Algorithms and Sparse Regularization for Synthetic Aperture Radar Imaging

    Science.gov (United States)

    2015-10-26

    AFRL-AFOSR-VA-TR-2015-0343 New Algorithms and Sparse Regularization for Synthetic Aperture Radar Imaging Laurent Demanet MASSACHUSETTS INSTITUTE OF...26-10-2015 2. REPORT TYPE Final Performance 3. DATES COVERED (From - To) 14-06-2014 to 14-06-2015 4. TITLE AND SUBTITLE New Algorithms and Sparse...method must fail -- at the target detection task. The analysis identifies the algorithms that perform well, and those that don’t, even in the case of

  15. Thermalnet: a Deep Convolutional Network for Synthetic Thermal Image Generation

    Science.gov (United States)

    Kniaz, V. V.; Gorbatsevich, V. S.; Mizginov, V. A.

    2017-05-01

    Deep convolutional neural networks have dramatically changed the landscape of the modern computer vision. Nowadays methods based on deep neural networks show the best performance among image recognition and object detection algorithms. While polishing of network architectures received a lot of scholar attention, from the practical point of view the preparation of a large image dataset for a successful training of a neural network became one of major challenges. This challenge is particularly profound for image recognition in wavelengths lying outside the visible spectrum. For example no infrared or radar image datasets large enough for successful training of a deep neural network are available to date in public domain. Recent advances of deep neural networks prove that they are also capable to do arbitrary image transformations such as super-resolution image generation, grayscale image colorisation and imitation of style of a given artist. Thus a natural question arise: how could be deep neural networks used for augmentation of existing large image datasets? This paper is focused on the development of the Thermalnet deep convolutional neural network for augmentation of existing large visible image datasets with synthetic thermal images. The Thermalnet network architecture is inspired by colorisation deep neural networks.

  16. Modifications to the synthetic aperture microwave imaging diagnostic

    Science.gov (United States)

    Brunner, K. J.; Chorley, J. C.; Dipper, N. A.; Naylor, G.; Sharples, R. M.; Taylor, G.; Thomas, D. A.; Vann, R. G. L.

    2016-11-01

    The synthetic aperture microwave imaging diagnostic has been operating on the MAST experiment since 2011. It has provided the first 2D images of B-X-O mode conversion windows and showed the feasibility of conducting 2D Doppler back-scattering experiments. The diagnostic heavily relies on field programmable gate arrays to conduct its work. Recent successes and newly gained experience with the diagnostic have led us to modify it. The enhancements will enable pitch angle profile measurements, O and X mode separation, and the continuous acquisition of 2D DBS data. The diagnostic has also been installed on the NSTX-U and is acquiring data since May 2016.

  17. Adaptive Receive and Transmit Apodization for Synthetic Aperture Ultrasound Imaging

    DEFF Research Database (Denmark)

    Holfort, Iben Kraglund; Austeng, Andreas; Synnevåg, Johan-Fredrik

    2009-01-01

    This paper suggests a framework for utilizing adaptive, data-dependent apodization weights on both the receiving and transmitting aperture for Synthetic Aperture (SA) ultrasound imaging. The suggested approach is based on the Minimum Variance (MV) beamformer and consists of two steps. A set...... emission images before summation. The method is investigated using simulated SA ultrasound data obtained using Field II. Data of 13 point targets distributed at depths from 40 mm to 70 mm, and a 5.5 MHz, 64-element linear array transducer have been used. The investigation has shown that the introduction...

  18. Synthetic aperture radar images with composite azimuth resolution

    Energy Technology Data Exchange (ETDEWEB)

    Bielek, Timothy P; Bickel, Douglas L

    2015-03-31

    A synthetic aperture radar (SAR) image is produced by using all phase histories of a set of phase histories to produce a first pixel array having a first azimuth resolution, and using less than all phase histories of the set to produce a second pixel array having a second azimuth resolution that is coarser than the first azimuth resolution. The first and second pixel arrays are combined to produce a third pixel array defining a desired SAR image that shows distinct shadows of moving objects while preserving detail in stationary background clutter.

  19. Limitations of synthetic aperture laser optical feedback imaging

    CERN Document Server

    Glastre, Wilfried; Hugon, Olivier; De Chatellus, Hugues Guillet; Lacot, Eric

    2012-01-01

    In this paper we present the origin and the effect of amplitude and phase noise on Laser Optical Feedback Imaging (LOFI) associated with Synthetic Aperture (SA) imaging system. Amplitude noise corresponds to photon noise and acts as an additive noise, it can be reduced by increasing the global measurement time. Phase noise can be divided in three families: random, sinusoidal and drift phase noise; we show that it acts as a multiplicative noise. We explain how we can reduce it by making oversampling or multiple measurements depending on its type. This work can easily be extended to all SA systems (Radar, Laser or Terahertz), especially when raw holograms are acquired point by point.

  20. Apodized RFI filtering of synthetic aperture radar images

    Energy Technology Data Exchange (ETDEWEB)

    Doerry, Armin Walter

    2014-02-01

    Fine resolution Synthetic Aperture Radar (SAR) systems necessarily require wide bandwidths that often overlap spectrum utilized by other wireless services. These other emitters pose a source of Radio Frequency Interference (RFI) to the SAR echo signals that degrades SAR image quality. Filtering, or excising, the offending spectral contaminants will mitigate the interference, but at a cost of often degrading the SAR image in other ways, notably by raising offensive sidelobe levels. This report proposes borrowing an idea from nonlinear sidelobe apodization techniques to suppress interference without the attendant increase in sidelobe levels. The simple post-processing technique is termed Apodized RFI Filtering (ARF).

  1. Interferometric Synthetic Aperture Microscopy: Computed Imaging for Scanned Coherent Microscopy

    Directory of Open Access Journals (Sweden)

    Stephen A. Boppart

    2008-06-01

    Full Text Available Three-dimensional image formation in microscopy is greatly enhanced by the use of computed imaging techniques. In particular, Interferometric Synthetic Aperture Microscopy (ISAM allows the removal of out-of-focus blur in broadband, coherent microscopy. Earlier methods, such as optical coherence tomography (OCT, utilize interferometric ranging, but do not apply computed imaging methods and therefore must scan the focal depth to acquire extended volumetric images. ISAM removes the need to scan the focus by allowing volumetric image reconstruction from data collected at a single focal depth. ISAM signal processing techniques are similar to the Fourier migration methods of seismology and the Fourier reconstruction methods of Synthetic Aperture Radar (SAR. In this article ISAM is described and the close ties between ISAM and SAR are explored. ISAM and a simple strip-map SAR system are placed in a common mathematical framework and compared to OCT and radar respectively. This article is intended to serve as a review of ISAM, and will be especially useful to readers with a background in SAR.

  2. Synthetic vision using polarization-sensitive thermal imaging

    Science.gov (United States)

    Chun, Cornell S. L.; Fleming, David L.; Harvey, W. A.; Torok, E. J.; Sadjadi, Firooz A.

    1996-05-01

    Landing of aircraft in inclement weather and taxiing operation in the presence of copious obstacles is a major issues in air traffic control for both military and civilian aviation. Onboard sensors are needed to penetrate smoke, fog, and haze and to provide enough resolution for the automated detection and recognition of runways and obstacles. The performance of automatic target recognition (ATR) systems using thermal infrared (FLIR) images is limited by the low contrast in intensity for terrestrial scenes. We are developing a thermal imaging technique where, in each image pixel, a combination of intensity and polarization data is captured simultaneously. Images of polarization have useful contrast for different surface orientations. This contrast should facilitate image segmentation and classification of objects. In this paper, we will describe a combination of two innovative technologies: a polarization-sensitive thermal imaging sensor and a suite of polarimetric specific automatic object detection and recognition algorithms. The sensor has been able to capture polarization data from thermal emissions of automobiles. Surface orientations can be measured in the same image frame as temperature distribution. For the evaluation of the algorithms a set of performance metrics will be defined. We will discuss our evaluation of the algorithms on synthetic images as would be captured with the polarization-sensitive sensor. We will compare the polarimetric specific ATR performance with the performance of conventional FLIR-based ATR.

  3. Novel fringe scanning/Fourier transform method of synthetic imaging

    Energy Technology Data Exchange (ETDEWEB)

    Crawford, T.M.; Albano, R.K.

    1993-08-01

    We have developed a one-dimensional theory and a computer model for synthetically imaging scenes using a novel fringe scanning/Fourier transform technique. Our method probes a scene using two interfering beams of slightly different frequency. These beams form a moving fringe pattern which scans the scene and resonates with any spatial frequency components having the same spatial frequency as the scanning fringe pattern. A simple, non-imaging detector above the scene observes any scattered radiation from the scene falling onto it. If a resonance occurs between the scanning fringe pattern and the scene, then the scattered radiation will be modulated at the difference frequency between the two probing beams. By changing the spatial period of the fringe pattern and then measuring the amplitude and phase of the modulated radiation that is scattered from the scene, the Fourier amplitudes and phases of the different spatial frequency components making up the scene can be measured. A synthetic image of the scene being probed can be generated from this Fourier amplitude and phase data by taking the inverse Fourier transform of this information. This technique could be used to image objects using light, ultrasonic, or other electromagnetic or acoustic waves.

  4. Synthetic strategies for controlling inter- and intramolecular interactions: Applications in single-molecule fluorescence imaging, bioluminescence imaging, and palladium catalysis

    Science.gov (United States)

    Conley, Nicholas R.

    The field of synthetic organic chemistry has reached such maturity that, with sufficient effort and resources, the synthesis of virtually any small molecule which exhibits reasonable stability at room temperature can be realized. While representing a monumental achievement for the field, the ability to exert precise control over molecular structure is just a means to an end, and it is frequently the responsibility of the synthetic chemist to determine which molecules should actually be synthesized. For better or worse, there exists no competitive free market in academia for new molecules, and as a result, the decision of which compounds should be synthesized is seldom driven by the forces of supply and demand; rather, it is guided by the synthetic chemist's interest in an anticipated structure-function relationship or in the properties of a previously unstudied class of molecules. As a consequence, there exists a pervasive need for chemists with synthetic expertise in fields (e.g., molecular imaging) and subdisciplines of chemistry (e.g., physical chemistry) in which the identification of promising synthetic targets dramatically outpaces the synthetic output in that field or subdiscipline, and ample opportunities are available for synthetic chemists who choose to pursue such cross-disciplinary research. This thesis describes synthetic efforts that leverage these opportunities to realize applications in biological imaging and in palladium catalysis. In Part I, the synthesis and characterization of three novel luminophores and their imaging applications are discussed. The first is a molecular beacon that utilizes a fluorophorefluorophore pair which exhibits H-dimer quenching in the closed conformation. This probe offers several advantages over conventional fluorophore-quencher molecular beacons in the detection of oligonucleotides, both in bulk and at the single-molecule level. Secondly, a fluorescent, Cy3-Cy5 covalent heterodimer is reported, which on account of the

  5. High-resolution imaging with a real-time synthetic aperture ultrasound system: a phantom study

    Science.gov (United States)

    Huang, Lianjie; Labyed, Yassin; Simonetti, Francesco; Williamson, Michael; Rosenberg, Robert; Heintz, Philip; Sandoval, Daniel

    2011-03-01

    It is difficult for ultrasound to image small targets such as breast microcalcifications. Synthetic aperture ultrasound imaging has recently developed as a promising tool to improve the capabilities of medical ultrasound. We use two different tissueequivalent phantoms to study the imaging capabilities of a real-time synthetic aperture ultrasound system for imaging small targets. The InnerVision ultrasound system DAS009 is an investigational system for real-time synthetic aperture ultrasound imaging. We use the system to image the two phantoms, and compare the images with those obtained from clinical scanners Acuson Sequoia 512 and Siemens S2000. Our results show that synthetic aperture ultrasound imaging produces images with higher resolution and less image artifacts than Acuson Sequoia 512 and Siemens S2000. In addition, we study the effects of sound speed on synthetic aperture ultrasound imaging and demonstrate that an accurate sound speed is very important for imaging small targets.

  6. Deep UV Native Fluorescence Imaging of Antarctic Cryptoendolithic Communities

    Science.gov (United States)

    Storrie-Lombardi, M. C.; Douglas, S.; Sun, H.; McDonald, G. D.; Bhartia, R.; Nealson, K. H.; Hug, W. F.

    2001-01-01

    An interdisciplinary team at the Jet Propulsion Laboratory Center for Life Detection has embarked on a project to provide in situ chemical and morphological characterization of Antarctic cryptoendolithic microbial communities. We present here in situ deep ultraviolet (UV) native fluorescence and environmental scanning electron microscopy images transiting 8.5 mm into a sandstone sample from the Antarctic Dry Valleys. The deep ultraviolet imaging system employs 224.3, 248.6, and 325 nm lasers to elicit differential fluorescence and resonance Raman responses from biomolecules and minerals. The 224.3 and 248.6 nm lasers elicit a fluorescence response from the aromatic amino and nucleic acids. Excitation at 325 nm may elicit activity from a variety of biomolecules, but is more likely to elicit mineral fluorescence. The resultant fluorescence images provide in situ chemical and morphological maps of microorganisms and the associated organic matrix. Visible broadband reflectance images provide orientation against the mineral background. Environmental scanning electron micrographs provided detailed morphological information. The technique has made possible the construction of detailed fluorescent maps extending from the surface of an Antarctic sandstone sample to a depth of 8.5 mm. The images detect no evidence of microbial life in the superficial 0.2 mm crustal layer. The black lichen component between 0.3 and 0.5 mm deep absorbs all wavelengths of both laser and broadband illumination. Filamentous deep ultraviolet native fluorescent activity dominates in the white layer between 0.6 mm and 5.0 mm from the surface. These filamentous forms are fungi that continue into the red (iron-rich) region of the sample extending from 5.0 to 8.5 mm. Using differential image subtraction techniques it is possible to identify fungal nuclei. The ultraviolet response is markedly attenuated in this region, apparently from the absorption of ultraviolet light by iron-rich particles coating

  7. Microlocal aspects of bistatic synthetic aperture radar imaging

    CERN Document Server

    Krishnan, Venky P

    2010-01-01

    In this article, we analyze the microlocal properties of the linearized forward scattering operator $F$ and the reconstruction operator $F^{*}F$ appearing in bistatic synthetic aperture radar imaging. In our model, the radar source and detector travel along a line a fixed distance apart. We show that $F$ is a Fourier integral operator, and we give the mapping properties of the projections from the canonical relation of $F$, showing that the right projection is a blow-down and the left projection is a fold. We then show that $F^{*}F$ is a singular FIO belonging to the class $I^{3,0}$.

  8. Multielement Synthetic Transmit Aperture Imaging Using Temporal Encoding

    DEFF Research Database (Denmark)

    Gammelmark, Kim; Jensen, Jørgen Arendt

    2003-01-01

    are performed using our experimental multichannel ultrasound scanning system, RASMUS. The designed linear FM signal obtains temporal sidelobes below -55 dB, and SNR investigations show improvements of 4-12 dB. A 30 turn (approximate to45%) increase in penetration depth is obtained on a multitarget phantom......A new method to increase the signal-to-noise ratio (SNR) of synthetic transmit aperture imaging is investigated. The approach utilizes multiple elements to emulate a spherical wave, and the conventional short excitation pulse is replaced by a linear frequency-modulated (FM) signal. The approach...

  9. Spatially variant apodization for squinted synthetic aperture radar images.

    Science.gov (United States)

    Castillo-Rubio, Carlos F; Llorente-Romano, Sergio; Burgos-García, Mateo

    2007-08-01

    Spatially variant apodization (SVA) is a nonlinear sidelobe reduction technique that improves sidelobe level and preserves resolution at the same time. This method implements a bidimensional finite impulse response filter with adaptive taps depending on image information. Some papers that have been previously published analyze SVA at the Nyquist rate or at higher rates focused on strip synthetic aperture radar (SAR). This paper shows that traditional SVA techniques are useless when the sensor operates with a squint angle. The reasons for this behaviour are analyzed, and a new implementation that largely improves the results is presented. The algorithm is applied to simulated SAR images in order to demonstrate the good quality achieved along with efficient computation.

  10. Frequency division transmission imaging and synthetic aperture reconstruction.

    Science.gov (United States)

    Gran, Fredrik; Jensen, Jørgen Arendt

    2006-05-01

    In synthetic transmit aperture imaging only a few transducer elements are used in every transmission, which limits the signal-to-noise ratio (SNR). The penetration depth can be increased by using all transmitters in every transmission. In this paper, a method for exciting all transmitters in every transmission and separating them at the receiver is proposed. The coding is done by designing narrow-band linearly frequency modulated signals, which are approximately disjointed in the frequency domain and assigning one waveform to each transmitter. By designing a filterbank consisting of the matched filters corresponding to the excitation waveforms, the different transmitters can be decoded at the receiver. The matched filter of a specific waveform will allow information only from this waveform to pass through, thereby separating it from the other waveforms. This means that all transmitters can be used in every transmission, and the information from the different transmitters can be separated instantaneously. Compared to traditional synthetic transmit aperture (STA) imaging, in which the different transmitters are excited sequentially, more energy is transmitted in every transmission, and a better signal-to-noise-ratio is attained. The method has been tested in simulation, in which the resolution and contrast was compared to a standard synthetic transmit aperture system with a single sinusoid excitation. The resolution and contrast was comparable for the two systems. The method also has been tested using the experimental ultrasound scanner RASMUS. The resolution was evaluated using a string phantom. The method was compared to a conventional STA using both sinusoidal excitation and linear frequency modulated (FM) signals as excitation. The system using the FM signals and the frequency division approach yielded the same performance concerning both axial (of approximately equal to 3 wavelengths) and lateral resolution (of approximately equal to 4.5 wavelengths). A SNR

  11. Forward imaging for obstacle avoidance using ultrawideband synthetic aperture radar

    Science.gov (United States)

    Nguyen, Lam H.; Wong, David C.; Stanton, Brian; Smith, Gregory

    2003-09-01

    In support of the Army vision for increased mobility, survivability, and lethality, we are investigating the use of ultra-wideband (UWB) synthetic aperture radar (SAR) technology to enhance unmanned ground vehicle missions. The ability of UWB radar technology to detect objects concealed by foilage could provide an important obstacle avoidance capability for robotic vehicles. This would improve the speed and maneuverability of these vehicles and consequently increase the probability of survivability of U.S. forces. This technology would address the particular challenges that confront robotic vehicles such as large rocks hidden in tall grass and voids such as ditches and bodies of water. ARL has designed and constructed an instrumentation-grade low frequency, UWB synthetic aperture radar for evaluation of the target signatures and underlying phenomenology of stationary tactical targets concealed by foilage and objects buried in the ground. The radar (named BoomSAR) is installed in teh basekt of a 30-ton boom lift and can be operated while the entire boom lift is driven forward slowly, with the boom arm extended as high as 45 m to generate a synthetic aperture. In this paper, we investigate the potential use of the UWB radar in the forward imaging configuration. The paper describes the forward imaging radar and test setup at Aberdeen Proving Ground, Maryland. We present imagery of "positive" obstacles such as trees, fences, wires, mines, etc., as well as "negative" obstacles such as ditches. Imagery of small targets such as plastic mines is also included. We provide eletromagnetic simulations of forward SAR imagery of plastic mines and compare that to the measurement data.

  12. Passive synthetic aperture imaging with limited noise sources

    Science.gov (United States)

    Garnier, Josselin

    2016-09-01

    We consider a passive synthetic aperture imaging problem. A single moving receiver antenna records random signals generated by one or several distant noise sources and backscattered by one or several reflectors. The sources emit noise signals modeled by stationary random processes. The reflectors can be imaged by summing the autocorrelation functions of the received signals computed over successive time windows, corrected for Doppler factors and migrated by appropriate travel times. In particular, the Doppler effect plays an important role and it can be used for resolution enhancement. When the noise source positions are not known, the reflector can be localized with an accuracy proportional to the reciprocal of the noise bandwidth, even when only a very small number of sources are available. When the noise source positions are known, the reflector can be localized with a cross range resolution proportional to the carrier wavelength and inversely proportional to the length of the receiver trajectory (i.e. the synthetic aperture), and with a range resolution proportional to the reciprocal of the bandwidth, even with only one noise source.

  13. Three-dimensional imaging using differential synthetic aperture interferometry

    Science.gov (United States)

    Zhang, Ning; Zhou, Yu; Sun, Jianfeng; Zhi, Ya'nan; Lu, Zhiyong; Xu, Qian; Sun, Zhiwei; Liu, Liren

    2014-09-01

    Synthetic aperture radar interferometry (InSAR) can gain three-dimensional topography with high spatial resolution and height accuracy using across track interferometry[1]. Conventional InSAR produce three-dimensional images from SAR data. But when the working wavelength transit from microwave to optical wave, the transmission antenna and receive antenna become very sensitive to platform vibration and beam quality[2]. Through differential receive antenna formation, we can relax the requirement of platform and laser using synthetic aperture imaging ladar (SAIL) concept[3]. Line-of-sight motion constraints are reduced by several orders of magnitude. We introduce two distinctive forms of antenna formation according to the position of interferogram. The first architecture can simplify the interferogram processing and phase extraction algorithm under time-division multiplex operation. The second architecture can process the 2D coordinate and height coordinate at the same time. Using optical diffraction theory, a systematic theory of side-looking SAIL is mathematically formulated and the necessary conditions for assuring a correct phase history are established[4]. Based on optical transformation and regulation of wavefront, a side-looking SAIL of two distinctive architectures is invented and the basic principle, systematic theory, design equations and necessary conditions are presented. It is shown that high height accuracy can be reached and the influences from atmospheric turbulence and unmodeled line-of-sight motion can be automatically compensated.

  14. In-vivo synthetic aperture flow imaging in medical ultrasound.

    Science.gov (United States)

    Nikolov, Svetoslav Ivanov; Jensen, Jørgen Arendt

    2003-07-01

    A new method for acquiring flow images using synthetic aperture techniques in medical ultrasound is presented. The new approach makes it possible to have a continuous acquisition of flow data throughout the whole image simultaneously, and this can significantly improve blood velocity estimation. Any type of filter can be used for discrimination between tissue and blood flow without initialization, and the number of lines used for velocity estimation is limited only by the nonstationarity of the flow. The new approach is investigated through both simulations and measurements. A flow rig is used for generating a parabolic laminar flow, and a research scanner is used for acquiring RF data from individual transducer elements. A reference profile is calculated from a mass flow meter. The parabolic velocity profile is estimated using the new approach with a relative standard deviation of 2.2% and a mean relative bias of 3.4% using 24 pulse emissions at a flow angle of 45 degrees. The 24 emissions can be used for making a full-color flow map image. An in-vivo image of flow in the carotid artery for a 29-year-old male also is presented. The full image is acquired using 24 emissions.

  15. Logarithmic Laplacian Prior Based Bayesian Inverse Synthetic Aperture Radar Imaging

    Directory of Open Access Journals (Sweden)

    Shuanghui Zhang

    2016-04-01

    Full Text Available This paper presents a novel Inverse Synthetic Aperture Radar Imaging (ISAR algorithm based on a new sparse prior, known as the logarithmic Laplacian prior. The newly proposed logarithmic Laplacian prior has a narrower main lobe with higher tail values than the Laplacian prior, which helps to achieve performance improvement on sparse representation. The logarithmic Laplacian prior is used for ISAR imaging within the Bayesian framework to achieve better focused radar image. In the proposed method of ISAR imaging, the phase errors are jointly estimated based on the minimum entropy criterion to accomplish autofocusing. The maximum a posterior (MAP estimation and the maximum likelihood estimation (MLE are utilized to estimate the model parameters to avoid manually tuning process. Additionally, the fast Fourier Transform (FFT and Hadamard product are used to minimize the required computational efficiency. Experimental results based on both simulated and measured data validate that the proposed algorithm outperforms the traditional sparse ISAR imaging algorithms in terms of resolution improvement and noise suppression.

  16. Three-dimensional synthetic aperture particle image velocimetry

    Science.gov (United States)

    Belden, Jesse; Truscott, Tadd T.; Axiak, Michael C.; Techet, Alexandra H.

    2010-12-01

    We present a new method for resolving three-dimensional (3D) fluid velocity fields using a technique called synthetic aperture particle image velocimetry (SAPIV). By fusing methods from the imaging community pertaining to light field imaging with concepts that drive experimental fluid mechanics, SAPIV overcomes many of the inherent challenges of 3D particle image velocimetry (3D PIV). This method offers the ability to digitally refocus a 3D flow field at arbitrary focal planes throughout a volume. The viewable out-of-plane dimension (Z) can be on the same order as the viewable in-plane dimensions (X-Y), and these dimensions can be scaled from tens to hundreds of millimeters. Furthermore, the digital refocusing provides the ability to 'see-through' partial occlusions, enabling measurements in densely seeded volumes. The advantages are achieved using a camera array (typically at least five cameras) to image the seeded fluid volume. The theoretical limits on refocused plane spacing and viewable depth are derived and explored as a function of camera optics and spacing of the array. A geometric optics model and simulated PIV images are used to investigate system performance for various camera layouts, measurement volume sizes and seeding density; performance is quantified by the ability to reconstruct the 3D intensity field, and resolve 3D vector fields in densely seeded simulated flows. SAPIV shows the ability to reconstruct fields with high seeding density and large volume size. Finally, results from an experimental implementation of SAPIV using a low cost eight-camera array to study a vortex ring in a 65 × 40 × 32 mm3 volume are presented. The 3D PIV results are compared with 2D PIV data to demonstrate the capability of the 3D SAPIV technique.

  17. Frequency division transmission imaging and synthetic aperture reconstruction

    DEFF Research Database (Denmark)

    Gran, Fredrik; Jensen, Jørgen Arendt

    2006-01-01

    corresponding to the excitation waveforms, the different transmitters can be decoded at the receiver. The matched filter of a specific waveform will allow information only from this waveform to pass through, thereby separating it from the other waveforms. This means that all transmitters can be used in every......In synthetic transmit aperture imaging only a few transducer elements are used in every transmission, which limits the signal-to-noise ratio (SNR). The penetration depth can be increased by using all transmitters in every transmission. In this paper, a method for exciting all transmitters in every...... transmission and separating them at the receiver is proposed. The coding is done by designing narrow-band linearly frequency modulated signals, which are approximately disjointed in the frequency domain and assigning one waveform to each transmitter. By designing a filterbank consisting of the matched filters...

  18. Estimation of velocity vectors in synthetic aperture ultrasound imaging

    DEFF Research Database (Denmark)

    Jensen, Jørgen Arendt; Oddershede, Niels

    2006-01-01

    A method for determining both velocity magnitude and angle in a synthetic aperture ultrasound system is described. The approach uses directional beamforming along the flow direction and cross-correlation to determine velocity magnitude. The angle of the flow is determined from the maximum...... of the visually determined flow angle. The standard deviation of these estimates was below 2.7 deg. Full color flow maps from different parts of the cardiac cycle are presented, including vector arrows indicating both estimated flow direction and velocity magnitude....... normalized correlation calculated as a function of angle. This assumes the flow direction is within the imaging plane. Simulations of the angle estimation method show both biases and standard deviations of the flow angle estimates below 3 deg for flow angles from 20 deg to 90 deg (transverse flow...

  19. Hierarchical model-based interferometric synthetic aperture radar image registration

    Science.gov (United States)

    Wang, Yang; Huang, Haifeng; Dong, Zhen; Wu, Manqing

    2014-01-01

    With the rapid development of spaceborne interferometric synthetic aperture radar technology, classical image registration methods are incompetent for high-efficiency and high-accuracy masses of real data processing. Based on this fact, we propose a new method. This method consists of two steps: coarse registration that is realized by cross-correlation algorithm and fine registration that is realized by hierarchical model-based algorithm. Hierarchical model-based algorithm is a high-efficiency optimization algorithm. The key features of this algorithm are a global model that constrains the overall structure of the motion estimated, a local model that is used in the estimation process, and a coarse-to-fine refinement strategy. Experimental results from different kinds of simulated and real data have confirmed that the proposed method is very fast and has high accuracy. Comparing with a conventional cross-correlation method, the proposed method provides markedly improved performance.

  20. Synthetic. cap alpha. subunit peptide 125-147 of human nicotinic acetylcholine receptor induces antibodies to native receptor

    Energy Technology Data Exchange (ETDEWEB)

    McCormick, D.J.; Griesmann, G.E.; Huang, Z.; Lennon, V.A.

    1986-03-05

    A synthetic peptide corresponding to residues 125-147 of the Torpedo acetylcholine receptor (AChR) ..cap alpha.. subunit proved to be a major antigenic region of the AChR. Rats inoculated with 50 ..mu..g of peptide (T ..cap alpha.. 125-147) developed T cell immunity and antibodies to native AChR and signs of experimental autoimmune myasthenia gravis. They report the synthesis and preliminary testing of a disulfide-looped peptide comprising residues 125-147 of the human AChR ..cap alpha.. subunit. Peptide H ..cap alpha.. 125-147 differs from T ..cap alpha.. 125-147 at residues 139 (Glu for Gln) and 143 (Ser for Thr). In immunoprecipitation assays, antibodies to Torpedo AChR bound /sup 125/I-labelled H..cap alpha.. 125-147 antibody bound H..cap alpha.. 125-147, but monoclonal antibodies to an immunodominant region of native AChR bound neither H..cap alpha.. 125-147 nor T ..cap alpha.. 125-147. Rats immunized with H ..cap alpha.. 125-147 produced anti-mammalian muscle AChR antibodies that induced modulation of AChRs from cultured human myotubes. Thus, region 125-147 of the human AChR ..cap alpha.. subunit is extracellular in muscle, and is both antigenic and immunogenic. It remains to be determined whether or not autoantibodies to this region may in part cause the weakness or myasthenia gravis in man.

  1. Imaging of contact acoustic nonlinearity using synthetic aperture technique.

    Science.gov (United States)

    Yun, Dongseok; Kim, Jongbeom; Jhang, Kyung-Young

    2013-09-01

    The angle beam incidence and reflection technique for the evaluation of contact acoustic nonlinearity (CAN) at solid-solid contact interfaces (e.g., closed cracks) has recently been developed to overcome the disadvantage of accessing both the inner and outer surfaces of structures for attaching pulsing and receiving transducers in the through-transmission of normal incidence technique. This paper proposes a technique for B-mode imaging of CAN based on the above reflection technique, which uses the synthetic aperture focusing technique (SAFT) and short-time Fourier transform (STFT) to visualize the distribution of the CAN-induced second harmonic magnitude as well as the nonlinear parameter. In order to verify the usefulness of the proposed method, a solid-solid contact interface was tested and the change of the contact acoustic nonlinearity according to the increasing contact pressure was visualized in images of the second harmonic magnitude and the relative nonlinear parameter. The experimental results showed good agreement with the previously developed theory identifying the dependence of the scattered second harmonics on the contact pressure. This technique can be used for the detection and improvement of the sizing accuracy of closed cracks that are difficult to detect using the conventional linear ultrasonic technique.

  2. Moving target imaging using ultrawideband synthetic aperture radar

    Science.gov (United States)

    Guo, Hanwei; Liang, Diannong; Wan, Yan; Huang, Xiaotao; Dong, Zhen

    2003-09-01

    Moving Target High Resolution Imaging of Foliage Penetrate Ultra-Wide Band Synthetic Aperture Radar (FOPEN UWB SAR) is of great significance for battlefield awareness of concealed target. Great range migration and strong clutter make moving target detection and imaging difficult, especially the Signal to Clutter Ration(SCR) some times is so low that the moving targets is invisible in FOPEN UWB SAR imagery. To improve SCR, the clean technique is used in range compressed data domain. The clean technique and data reconstruction help single channel of FOPEN UWB SAR suppress strong tree clutter and stationary target signal from region of interest. A new definition called General Key-Stone Transform is given, which can correct any order of range migration. FOPEN UWB SAR has long integrated time. The plane and target moving in long time lead to complex range migration. To obtain high resolution imagery of moving target, General Key-Stone transform are applied to remove the range migration and realize multiple moving target data segment. Both General Key-Stone Transform and Clean Technique are applied in real data processing of FOPEN UWB SAR. The result shows that multiple moving targets in the trees are clearly detected and high resolution imagery is formed.

  3. Optical imaging process based on two-dimensional Fourier transform for synthetic aperture imaging ladar

    Science.gov (United States)

    Sun, Zhiwei; Zhi, Ya'nan; Liu, Liren; Sun, Jianfeng; Zhou, Yu; Hou, Peipei

    2013-09-01

    The synthetic aperture imaging ladar (SAIL) systems typically generate large amounts of data difficult to compress with digital method. This paper presents an optical SAIL processor based on compensation of quadratic phase of echo in azimuth direction and two dimensional Fourier transform. The optical processor mainly consists of one phase-only liquid crystal spatial modulator(LCSLM) to load the phase data of target echo and one cylindrical lens to compensate the quadratic phase and one spherical lens to fulfill the task of two dimensional Fourier transform. We show the imaging processing result of practical target echo obtained by a synthetic aperture imaging ladar demonstrator. The optical processor is compact and lightweight and could provide inherent parallel and the speed-of-light computing capability, it has a promising application future especially in onboard and satellite borne SAIL systems.

  4. The Lipid Moiety of Haemozoin (Malaria Pigment and P. falciparum Parasitised Red Blood Cells Bind Synthetic and Native Endothelin-1

    Directory of Open Access Journals (Sweden)

    Nicoletta Basilico

    2010-01-01

    Full Text Available Endothelin1 (ET-1 is a 21-amino acid peptide produced by the vascular endothelium under hypoxia, that acts locally as regulator of vascular tone and inflammation. The role of ET-1 in Plasmodium falciparum malaria is unknown, although tissue hypoxia is frequent as a result of the cytoadherence of parasitized red blood cell (pRBC to the microvasculature. Here, we show that both synthetic and endothelial-derived ET-1 are removed by parasitized RBC (D10 and W2 strains, chloroquine sensitive, and resistant, resp. and native haemozoin (HZ, malaria pigment, but not by normal RBC, delipidized HZ, or synthetic beta-haematin (BH. The effect is dose dependent, selective for ET-1, but not for its precursor, big ET-1, and not due to the proteolysis of ET-1. The results indicate that ET-1 binds to the lipids moiety of HZ and membranes of infected RBCs. These findings may help understanding the consequences of parasite sequestration in severe malaria.

  5. Inverse-synthetic-aperture imaging of trees over a ground plane

    Energy Technology Data Exchange (ETDEWEB)

    Zittel, D.H.; Brock, B.C.; Littlejohn, J.H.; Patitz, W.E.

    1995-11-01

    Recent data collections with the Sandia VHF-UHF synthetic-aperture radar have yielded surprising results; trees appear brighter in the images than expected! In an effort to understand this phenomenon, various small trees have been measured on the Sandia folded compact range with the inverse-synthetic-aperture imaging system. A compilation of these measurements is contained in this report.

  6. Polarimetric Synthetic Aperture Radar Image Classification by a Hybrid Method

    Institute of Scientific and Technical Information of China (English)

    Kamran Ullah Khan; YANG Jian

    2007-01-01

    Different methods proposed so far for accurate classification of land cover types in polarimetric synthetic aperture radar (SAR) image are data specific and no general method is available. A novel hybrid framework for this classification was developed in this work. A set of effective features derived from the coherence matrix of polarimetric SARdata was proposed.Constituents of the feature set are wavelet,texture,and nonlinear features.The proposed feature set has a strong discrimination power. A neural network was used as the classification engine in a unique way. By exploiting the speed of the conjugate gradient method and the convergence rate of the Levenberg-Marquardt method (near the optimal point), an overall speed up of the classification procedure was achieved. Principal component analysis(PCA)was used to shrink the dimension of the feature vector without sacrificing much of the classification accuracy. The proposed approach is compared with the maximum likelihood estimator (MLE)based on the complex Wishart distribution and the results show the superiority of the proposed method,with the average classification accuracy by the proposed method(95.4%)higher than that of the MLE(93.77%). Use of PCA to reduce the dimensionality of the feature vector helps reduce the memory requirements and computational cost, thereby enhancing the speed of the process.

  7. Synthetic

    Directory of Open Access Journals (Sweden)

    Anna Maria Manferdini

    2010-06-01

    Full Text Available Traditionally materials have been associated with a series of physical properties that can be used as inputs to production and manufacturing. Recently we witnessed an interest in materials considered not only as ‘true matter’, but also as new breeds where geometry, texture, tooling and finish are able to provoke new sensations when they are applied to a substance. These artificial materials can be described as synthetic because they are the outcome of various qualities that are not necessarily true to the original matter, but they are the combination of two or more parts, whether by design or by natural processes. The aim of this paper is to investigate the potential of architectural surfaces to produce effects through the invention of new breeds of artificial matter, using micro-scale details derived from Nature as an inspiration.

  8. Change detection in synthetic aperture radar images based on image fusion and fuzzy clustering.

    Science.gov (United States)

    Gong, Maoguo; Zhou, Zhiqiang; Ma, Jingjing

    2012-04-01

    This paper presents an unsupervised distribution-free change detection approach for synthetic aperture radar (SAR) images based on an image fusion strategy and a novel fuzzy clustering algorithm. The image fusion technique is introduced to generate a difference image by using complementary information from a mean-ratio image and a log-ratio image. In order to restrain the background information and enhance the information of changed regions in the fused difference image, wavelet fusion rules based on an average operator and minimum local area energy are chosen to fuse the wavelet coefficients for a low-frequency band and a high-frequency band, respectively. A reformulated fuzzy local-information C-means clustering algorithm is proposed for classifying changed and unchanged regions in the fused difference image. It incorporates the information about spatial context in a novel fuzzy way for the purpose of enhancing the changed information and of reducing the effect of speckle noise. Experiments on real SAR images show that the image fusion strategy integrates the advantages of the log-ratio operator and the mean-ratio operator and gains a better performance. The change detection results obtained by the improved fuzzy clustering algorithm exhibited lower error than its preexistences.

  9. Synthetically Evaluation System for Multi-source Image Fusion and Experimental Analysis

    Institute of Scientific and Technical Information of China (English)

    XIAO Gang; JING Zhong-liang; WU Jian-min; LIU Cong-yi

    2006-01-01

    Study on the evaluation system for multi-source image fusion is an important and necessary part of image fusion. Qualitative evaluation indexes and quantitative evaluation indexes were studied. A series of new concepts,such as independent single evaluation index, union single evaluation index, synthetic evaluation index were proposed. Based on these concepts, synthetic evaluation system for digital image fusion was formed. The experiments with the wavelet fusion method, which was applied to fuse the multi-spectral image and panchromatic remote sensing image, the IR image and visible image, the CT and MRI image, and the multi-focus images show that it is an objective, uniform and effective quantitative method for image fusion evaluation.

  10. Registration of images from a hull mounted, low frequency synthetic aperture sonar

    NARCIS (Netherlands)

    Bonnett, B.; Hayes, M.; Hunter, A.

    2013-01-01

    Coherent change detection between multiple synthetic aperture sonar (SAS) images is reliant on the images being co-registered with sub-pixel accuracy. In this paper we suggest a technique using available navigation data to reconstruct the images onto a common grid. Data obtained using the MUD SAS sy

  11. Enhanced reconstruction of partially occluded objects with occlusion removal in synthetic aperture integral imaging

    Institute of Scientific and Technical Information of China (English)

    Zhiliang Zhou; Yan Yuan; Xiangli Bin; Qian Wang

    2011-01-01

    @@ Synthetic aperture integral imaging provides the ability to reconstruct partially occluded objects from multi-view images.However, the reconstructed images suffer from degraded contrast due to the super-imposition of foreground defocus blur.We propose an algorithm to remove foreground occlusions before reconstructing backgrounds.Occlusions are identified by estimating the color variance on elemental im-ages and then deleting it in the final synthetic image.We demonstrate the superiority of our method by presenting experimental results as well as comparing our method with other approaches.%Synthetic aperture integral imaging provides the ability to reconstruct partially occluded objects from multi-view images. However, the reconstructed images suffer from degraded contrast due to the superimposition of foreground defocus blur. We propose an algorithm to remove foreground occlusions before reconstructing backgrounds. Occlusions are identified by estimating the color variance on elemental images and then deleting it in the final synthetic image. We demonstrate the superiority of our method by presenting experimental results as well as comparing our method with other approaches.

  12. Spectral characterization and discrimination of synthetic fibers with near-infrared hyperspectral imaging system.

    Science.gov (United States)

    Jin, Xiaoke; Memon, Hafeezullah; Tian, Wei; Yin, Qinli; Zhan, Xiaofang; Zhu, Chengyan

    2017-04-20

    Synthetic fibers account for about half of all fiber usage, with applications in every textile field. The phenomenon of fiber composition not matching the label harms consumer interests and impedes market development. Hyperspectral imaging technology as a potential technique can be utilized to discriminate mass synthetic fibers rapidly and nondestructively and achieves the functions that traditional Fourier transform infrared instruments do not have. On the basis of investigating the impact of dope-dyeing and wrapping processes on spectra, the spectral features (from 900 to 2500 nm) of six categories of synthetic fibers were extracted with a hyperspectral imaging system. A principal component analysis-linear discriminant analysis model was developed to discriminate the chemical content of fibers in different colors and structures, which showed 100% discrimination accuracy. Results demonstrated the feasibility of a hyperspectral imaging system in synthetic fiber discrimination. Therefore, this method offers a more convenient alternative for textile industry on-site discrimination.

  13. Preliminary study of synthetic aperture tissue harmonic imaging on in-vivo data

    DEFF Research Database (Denmark)

    Rasmussen, Joachim Hee; Hemmsen, Martin Christian; Sloth Madsen, Signe

    2013-01-01

    A method for synthetic aperture tissue harmonic imaging is investigated. It combines synthetic aperture sequential beamforming (SASB) with tissue harmonic imaging (THI) to produce an increased and more uniform spatial resolution and improved side lobe reduction compared to conventional B......-mode imaging. Synthetic aperture sequential beamforming tissue harmonic imaging (SASB-THI) was implemented on a commercially available BK 2202 Pro Focus UltraView ultrasound system and compared to dynamic receive focused tissue harmonic imaging (DRF-THI) in clinical scans. The scan sequence...... that was implemented on the UltraView system acquires both SASB-THI and DRF-THI simultaneously. Twenty-four simultaneously acquired video sequences of in-vivo abdominal SASB-THI and DRF-THI scans on 3 volunteers of 4 different sections of liver and kidney tissues were created. Videos of the in-vivo scans were...

  14. 2-D Tissue Motion Compensation of Synthetic Transmit Aperture Images

    DEFF Research Database (Denmark)

    Gammelmark, Kim Løkke; Jensen, Jørgen Arendt

    2014-01-01

    images recorded using the same emission sequence. The velocity and direction of the motion are found by crosscorrelating short high-resolution lines beamformed along selected angles. The motion acquisition is interleaved with the regular B-mode emissions in STA imaging, and the motion compensation...... be compensated for, and that doing so yields a significant increase in image quality....

  15. High Dynamic Range Image Based on Multiple Exposure Time Synthetization

    Directory of Open Access Journals (Sweden)

    Yoshifumi Shimodaira

    2007-03-01

    Full Text Available High dynamic range of illumination may cause serious distortions and otherproblems in viewing and further processing of digital images. In this paper a new tonereproduction preprocessing algorithm is introduced which may help in developing hardly ornon-viewable features and content of the images. The method is based on the synthetizationof multiple exposure images from which the dense part, i.e. regions having the maximumlevel of detail are included in the output image. The resulted high quality HDR image makeseasier the information extraction and effectively supports the further processing of theimage.

  16. Preliminary In-Vivo Evaluation of Convex Array Synthetic Aperture Imaging

    DEFF Research Database (Denmark)

    Pedersen, Morten Høgholm; Gammelmark, Kim; Jensen, Jørgen Arendt

    2004-01-01

    of STA imaging in comparison to conventional imaging. The purpose is to evaluate whether STA imaging is feasible in-vivo. and whether the image quality obtained is comparable to traditional scanned imaging in terms of penetration depth, spatial resolution, contrast resolution, and artifacts. Acquisition...... using randomized blinded presentation. Penetration and image quality were scored and evaluated statistically. Results show that in-vivo imaging using STA imaging is feasible with improved image quality compared to conventional imaging.......Synthetic transmit aperture (STA) imaging has previously been investigated and compared to traditional imaging techniques in simulations and phantom studies. However, a full in-vivo study evaluating its clinical potential has yet to be conducted. This paper presents a preliminary in-vivo study...

  17. Three-dimensional reconstruction of far and large objects using synthetic aperture integral imaging

    Science.gov (United States)

    Piao, Yongri; Xing, Luyan; Zhang, Miao; Lee, Byung-Gook

    2017-01-01

    In this paper, we present a three-dimensional reconstruction of far and large objects in a synthetic aperture integral imaging system. In the proposed method, the far and large size objects are recorded as a set of elemental images by using an additional Plano-concave lens in the synthetic aperture integral imaging system. Due to the use of the Plano-concave lens, the reconstruction distance can be significantly reduced. This enables us to computationally reconstruct the objects in the far-field region. Experimental results are carried out, and the feasibility of the proposed method is verified.

  18. Wavefront curvature limitations and compensation to polar format processing for synthetic aperture radar images.

    Energy Technology Data Exchange (ETDEWEB)

    Doerry, Armin Walter

    2006-01-01

    Limitations on focused scene size for the Polar Format Algorithm (PFA) for Synthetic Aperture Radar (SAR) image formation are derived. A post processing filtering technique for compensating the spatially variant blurring in the image is examined. Modifications to this technique to enhance its robustness are proposed.

  19. Improved Beamforming for Lateral Oscillations in Elastography Using Synthetic Aperture Imaging

    DEFF Research Database (Denmark)

    Liebgott, Hervé; Basarab, Adrian; Loizeau, Damien;

    2007-01-01

    In this paper we present a beamforming technique based on synthetic aperture imaging that enables to improve the radio-frequency (RF) ultrasound images with lateral oscillations for lateral displacement estimation. As described in previous work, in order to increase the accuracy of the lateral di...

  20. Basics of Polar-Format algorithm for processing Synthetic Aperture Radar images.

    Energy Technology Data Exchange (ETDEWEB)

    Doerry, Armin Walter

    2012-05-01

    The purpose of this report is to provide a background to Synthetic Aperture Radar (SAR) image formation using the Polar Format (PFA) processing algorithm. This is meant to be an aid to those tasked to implement real-time image formation using the Polar Format processing algorithm.

  1. Tissue section AFM: In situ ultrastructural imaging of native biomolecules

    Science.gov (United States)

    Graham, Helen K.; Hodson, Nigel W.; Hoyland, Judith A.; Millward-Sadler, Sarah J.; Garrod, David; Scothern, Anthea; Griffiths, Christopher E.M.; Watson, Rachel E.B.; Cox, Thomas R.; Erler, Janine T.; Trafford, Andrew W.; Sherratt, Michael J.

    2010-01-01

    Conventional approaches for ultrastructural high-resolution imaging of biological specimens induce profound changes in bio-molecular structures. By combining tissue cryo-sectioning with non-destructive atomic force microscopy (AFM) imaging we have developed a methodology that may be applied by the non-specialist to both preserve and visualize bio-molecular structures (in particular extracellular matrix assemblies) in situ. This tissue section AFM technique is capable of: i) resolving nm–µm scale features of intra- and extracellular structures in tissue cryo-sections; ii) imaging the same tissue region before and after experimental interventions; iii) combining ultrastructural imaging with complimentary microscopical and micromechanical methods. Here, we employ this technique to: i) visualize the macro-molecular structures of unstained and unfixed fibrillar collagens (in skin, cartilage and intervertebral disc), elastic fibres (in aorta and lung), desmosomes (in nasal epithelium) and mitochondria (in heart); ii) quantify the ultrastructural effects of sequential collagenase digestion on a single elastic fibre; iii) correlate optical (auto fluorescent) with ultrastructural (AFM) images of aortic elastic lamellae. PMID:20144712

  2. 3D Imaging Millimeter Wave Circular Synthetic Aperture Radar

    Science.gov (United States)

    Zhang, Renyuan; Cao, Siyang

    2017-01-01

    In this paper, a new millimeter wave 3D imaging radar is proposed. The user just needs to move the radar along a circular track, and high resolution 3D imaging can be generated. The proposed radar uses the movement of itself to synthesize a large aperture in both the azimuth and elevation directions. It can utilize inverse Radon transform to resolve 3D imaging. To improve the sensing result, the compressed sensing approach is further investigated. The simulation and experimental result further illustrated the design. Because a single transceiver circuit is needed, a light, affordable and high resolution 3D mmWave imaging radar is illustrated in the paper. PMID:28629140

  3. Optical slicing of large scenes by synthetic aperture integral imaging

    Science.gov (United States)

    Navarro, Héctor; Saavedra, Genaro; Molina, Ainhoa; Martínez-Corral, Manuel; Martínez-Cuenca, Raúl; Javidi, Bahram

    2010-04-01

    Integral imaging (InI) technology was created with the aim of providing the binocular observers of monitors, or matrix display devices, with auto-stereoscopic images of 3D scenes. However, along the last few years the inventiveness of researches has allowed to find many other interesting applications of integral imaging. Examples of this are the application of InI in object recognition, the mapping of 3D polarization distributions, or the elimination of occluding signals. One of the most interesting applications of integral imaging is the production of views focused at different depths of the 3D scene. This application is the natural result of the ability of InI to create focal stacks from a single input image. In this contribution we present new algorithm for this optical slicing application, and show that it is possible the 3D reconstruction with improved lateral resolution.

  4. Improve synthetic retinal OCT images with present of pathologies and textural information

    Science.gov (United States)

    Shahrian Varnousfaderani, Ehsan; Vogl, Wolf-Dieter; Wu, Jing; Gerendas, Bianca S.; Simader, Christian; Langs, Georg; Waldstein, Sebastian M.; Schmidt-Erfurth, Ursula

    2016-03-01

    The lack of noise free Optical Coherence Tomography (OCT) images makes it challenging to quantitatively evaluate performance of image processing methods such as denoising methods. The synthetic noise free OCT images are needed to evaluate performance of image processing methods. The current synthetic methods fail to generate synthetic images that represent real OCT images with present of pathologies. They cannot correctly imitate real OCT data due to a tendency to smooth the data, losing texture information and even, pathologies such as cysts are simply smoothed away by these methods. The first aim of this paper is to use mathematical models to generate a synthetic noise free image that represent real retinal OCT B-scan or volume with present of clinically important pathologies. The proposed method partitions a B-scan obtained from real OCT into three regions (vitreous, retina and choroid) by segmenting the inner limiting membrane (ILM) and retinal pigment epithelium (RPE) surfaces as well as cysts regions by medical experts. Then retina region is further divided into small blocks. Different smoothness functions are used to estimate OCT signals in vitreous, choroid and cyst regions and in blocks of retina region. Estimating signals in block resolution enables our proposed method to capture more textural information by using a simple mathematical model (smoothness function) and using annotated cyst enables our method to model cyst pathology accurately. The qualitative evaluations show that proposed method generates more realistic B-scans with present of pathologies and textural information than other methods.

  5. Apparatus and method for velocity estimation in synthetic aperture imaging

    DEFF Research Database (Denmark)

    2003-01-01

    by the object (4) and received by the elements of the transducer array (5). All of these signals are then combined in the beam processor (6) to focus all of the beams in the image in both transmit and receive mode and the simultaneously focused signals are used for updating the image in the processor (7......). The update signals are used in the velocity estimation processor (8) to correlate the individual measurements to obtain the displacement between high-resolution images and thereby determine the velocity....

  6. Information extraction and transmission techniques for spaceborne synthetic aperture radar images

    Science.gov (United States)

    Frost, V. S.; Yurovsky, L.; Watson, E.; Townsend, K.; Gardner, S.; Boberg, D.; Watson, J.; Minden, G. J.; Shanmugan, K. S.

    1984-01-01

    Information extraction and transmission techniques for synthetic aperture radar (SAR) imagery were investigated. Four interrelated problems were addressed. An optimal tonal SAR image classification algorithm was developed and evaluated. A data compression technique was developed for SAR imagery which is simple and provides a 5:1 compression with acceptable image quality. An optimal textural edge detector was developed. Several SAR image enhancement algorithms have been proposed. The effectiveness of each algorithm was compared quantitatively.

  7. Terahertz inverse synthetic aperture radar imaging using self-mixing interferometry with a quantum cascade laser.

    Science.gov (United States)

    Lui, H S; Taimre, T; Bertling, K; Lim, Y L; Dean, P; Khanna, S P; Lachab, M; Valavanis, A; Indjin, D; Linfield, E H; Davies, A G; Rakić, A D

    2014-05-01

    We propose a terahertz (THz)-frequency synthetic aperture radar imaging technique based on self-mixing (SM) interferometry, using a quantum cascade laser. A signal processing method is employed which extracts and exploits the radar-related information contained in the SM signals, enabling the creation of THz images with improved spatial resolution. We demonstrate this by imaging a standard resolution test target, achieving resolution beyond the diffraction limit.

  8. Experimental ultrasound system for real-time synthetic imaging

    DEFF Research Database (Denmark)

    Jensen, Jørgen Arendt; Holm, Ole; Jensen, Lars Joost

    1999-01-01

    Digital signal processing is being employed more and more in modern ultrasound scanners. This has made it possible to do dynamic receive focusing for each sample and implement other advanced imaging methods. The processing, however, has to be very fast and cost-effective at the same time. Dedicated...... chips are used in order to do real time processing. This often makes it difficult to implement radically different imaging strategies on one platform and makes the scanners less accessible for research purposes. Here flexibility is the prime concern, and the storage of data from all transducer elements......-element ultrasound transducers, and to enable real-time or near realtime processing of the acquired data. The system will be capable of performing the processing for the currently available imaging methods, and will make it possible to perform initial trials in a clinical environment with new imaging modalities...

  9. Optimum synthetic-aperture imaging of extended astronomical objects

    NARCIS (Netherlands)

    Van der Avoort, C.; Pereira, S.F.; Braat, J.J.M.; Den Herder, J.W.

    2007-01-01

    In optical aperture-synthesis imaging of stellar objects, different beam combination strategies are used and proposed. Coaxial Michelson interferometers are very common and a homothetic multiaxial interferometer is recently realized in the Large Binocular Telescope. Laboratory experiments have demon

  10. Harmonic ultrasound imaging using synthetic aperture sequential beamforming

    DEFF Research Database (Denmark)

    2012-01-01

    A method includes generating an ultrasound image based on the harmonic components in the received echoes using multi-stage beam forming and data generated therefrom. An ultrasound imaging system (100, 200) includes a transducer array (108) including a plurality of transducer elements configured...... to emit ultrasound signals and receive echoes generated in response to the emitted ultrasound signals. The ultrasound imaging system further includes transmit circuitry (1 10) that generates a set of pulses that actuate a set of the plurality of transducer elements to emit ultrasound signals....... The ultrasound imaging system further includes receive circuitry (1 12), including a first beam former (122) configured to process the second harmonic signal components extracted from the received echo signals, generating intermediate scan lines. Memory (126) stores the generated intermediate scan lines...

  11. Bistatic synthetic aperture radar imaging for arbitrary flight trajectories.

    Science.gov (United States)

    Yarman, Can Evren; Yazici, Birsen; Cheney, Margaret

    2008-01-01

    In this paper, we present an analytic, filtered backprojection (FBP) type inversion method for bistatic synthetic aperture radar (BISAR). We consider a BISAR system where a scene of interest is illuminated by electromagnetic waves that are transmitted, at known times, from positions along an arbitrary, but known, flight trajectory and the scattered waves are measured from positions along a different flight trajectory which is also arbitrary, but known. We assume a single-scattering model for the radar data, and we assume that the ground topography is known but not necessarily flat. We use microlocal analysis to develop the FBP-type reconstruction method. We analyze the computational complexity of the numerical implementation of the method and present numerical simulations to demonstrate its performance.

  12. Experimental ultrasound system for real-time synthetic imaging

    OpenAIRE

    1999-01-01

    Digital signal processing is being employed more and more in modern ultrasound scanners. This has made it possible to do dynamic receive focusing for each sample and implement other advanced imaging methods. The processing, however, has to be very fast and cost-effective at the same time. Dedicated chips are used in order to do real time processing. This often makes it difficult to implement radically different imaging strategies on one platform and makes the scanners less accessible for rese...

  13. Synthetic-aperture imaging laser radar: laboratory demonstration and signal processing.

    Science.gov (United States)

    Beck, Steven M; Buck, Joseph R; Buell, Walter F; Dickinson, Richard P; Kozlowski, David A; Marechal, Nicholas J; Wright, Timothy J

    2005-12-10

    The spatial resolution of a conventional imaging laser radar system is constrained by the diffraction limit of the telescope's aperture. We investigate a technique known as synthetic-aperture imaging laser radar (SAIL), which employs aperture synthesis with coherent laser radar to overcome the diffraction limit and achieve fine-resolution, long-range, two-dimensional imaging with modest aperture diameters. We detail our laboratory-scale SAIL testbed, digital signal-processing techniques, and image results. In particular, we report what we believe to be the first optical synthetic-aperture image of a fixed, diffusely scattering target with a moving aperture. A number of fine-resolution, well-focused SAIL images are shown, including both retroreflecting and diffuse scattering targets, with a comparison of resolution between real-aperture imaging and synthetic-aperture imaging. A general digital signal-processing solution to the laser waveform instability problem is described and demonstrated, involving both new algorithms and hardware elements. These algorithms are primarily data driven, without a priori knowledge of waveform and sensor position, representing a crucial step in developing a robust imaging system.

  14. Synthetic Aperture Flow Imaging Using a Dual Beamformer Approach

    DEFF Research Database (Denmark)

    Li, Ye

    Color flow mapping systems have become widely used in clinical applications. It provides an opportunity to visualize the velocity profile over a large region in the vessel, which makes it possible to diagnose, e.g., occlusion of veins, heart valve deficiencies, and other hemodynamic problems....... However, while the conventional ultrasound imaging of making color flow mapping provides useful information in many circumstances, the spatial velocity resolution and frame rate are limited. The entire velocity distribution consists of image lines from different directions, and each image line...... the capability of acquiring color flow mapping with a high frame rate. Secondly, the new method is extended to the vector velocity estimation using directional beamforming, which beamforms data in the flow direction. The magnitude of the flow can be obtained and results of simulations and phantom measurements...

  15. Simulation Study of Real Time 3-D Synthetic Aperture Sequential Beamforming for Ultrasound Imaging

    DEFF Research Database (Denmark)

    Hemmsen, Martin Christian; Rasmussen, Morten Fischer; Stuart, Matthias Bo;

    2014-01-01

    This paper presents a new beamforming method for real-time three-dimensional (3-D) ultrasound imaging using a 2-D matrix transducer. To obtain images with sufficient resolution and contrast, several thousand elements are needed. The proposed method reduces the required channel count from...... the transducer to the main imaging system, by including electronics in the transducer handle. The reduction of element channel count is achieved using a sequential beamforming scheme. The beamforming scheme is a combination of a fixed focus beamformer in the transducer and a second dynamic focus beamformer...... in the main system. The real-time imaging capability is achieved using a synthetic aperture beamforming technique, utilizing the transmit events to generate a set of virtual elements that in combination can generate an image. The two core capabilities in combination is named Synthetic Aperture Sequential...

  16. High Frame Rate Synthetic Aperture 3D Vector Flow Imaging

    DEFF Research Database (Denmark)

    Villagómez Hoyos, Carlos Armando; Holbek, Simon; Stuart, Matthias Bo

    2016-01-01

    3-D blood flow quantification with high spatial and temporal resolution would strongly benefit clinical research on cardiovascular pathologies. Ultrasonic velocity techniques are known for their ability to measure blood flow with high precision at high spatial and temporal resolution. However......, current volumetric ultrasonic flow methods are limited to one velocity component or restricted to a reduced field of view (FOV), e.g. fixed imaging planes, in exchange for higher temporal resolutions. To solve these problems, a previously proposed accurate 2-D high frame rate vector flow imaging (VFI......) technique is extended to estimate the 3-D velocity components inside a volume at high temporal resolutions (

  17. Synthetic aperture radar imaging algorithm customized for programmable optronic processor in the application of full-scene synthetic aperture radar image formation

    Science.gov (United States)

    Sheng, Hui; Gao, Yesheng; Zhu, Bingqi; Wang, Kaizhi; Liu, Xingzhao

    2015-01-01

    With the high programmability of a spatial light modulator (SLM), a newly developed synthetic aperture radar (SAR) optronic processor is capable of focusing SAR data with different parameters. The embedded SLM, encoding SAR data into light signal in the processor, has a limited loading resolution of 1920×1080. When the dimension of processed SAR data increases to tens of thousands in either range or azimuth direction, SAR data should be input and focused block by block. And then, part of the imaging results is mosaicked to offer a full-scene SAR image. In squint mode, however, Doppler centroid will shift signal spectrum in the azimuth direction and make phase filters, loaded by another SLM, unable to cover the entire signal spectrum. It brings about a poor imaging result. Meanwhile, the imaging result, shifted away from the center of light output, will cause difficulties in subsequent image mosaic. We present an SAR image formation algorithm designed to solve these problems when processing SAR data of a large volume in low-squint case. It could not only obtain high-quality imaging results, but also optimize the subsequent process of image mosaic with optimal system cost and efficiency. Experimental results validate the performance of this proposed algorithm in optical full-scene SAR imaging.

  18. Feature Understanding and Target Detection for Sparse Microwave Synthetic Aperture Radar Images

    Directory of Open Access Journals (Sweden)

    Zhang Zenghui

    2016-02-01

    Full Text Available Sparse microwave imaging using sparse priors of observed scenes in space, time, frequency, or polarization domain and echo data with sampling rate smaller than the traditional Nyquist rate as well as optimization algorithms for reconstructing the microwave images of observed scenes has many advantages over traditional microwave imaging systems. In sparse microwave imaging, image acquisition and representation vary; therefore, new feature analysis and cognitive interpretation theories and methods should be developed based on current research results. In this study, we analyze the statistical properties of sparse Synthetic Aperture Radar (SAR images and changes in point, line and regional features induced by sparse reconstruction. For SAR images recovered by the spatial sparse model, the statistical distribution degrades, whereas points and lines can be accurately extracted by low sampling rates. Furthermore, the target detection method based on sparse SAR images is studied. Owing to a weak background noise, target detection is easier using sparse SAR images than traditional ones.

  19. Autofocus correction of excessive migration in synthetic aperture radar images.

    Energy Technology Data Exchange (ETDEWEB)

    Doerry, Armin Walter

    2004-09-01

    When residual range migration due to either real or apparent motion errors exceeds the range resolution, conventional autofocus algorithms fail. A new migration-correction autofocus algorithm has been developed that estimates the migration and applies phase and frequency corrections to properly focus the image.

  20. Synthetic aperture imaging in astronomy and aerospace: introduction.

    Science.gov (United States)

    Creech-Eakman, Michelle J; Carney, P Scott; Buscher, David F; Shao, Michael

    2017-05-01

    Aperture synthesis methods allow the reconstruction of images with the angular resolutions exceeding that of extremely large monolithic apertures by using arrays of smaller apertures together in combination. In this issue we present several papers with techniques relevant to amplitude interferometry, laser radar, and intensity interferometry applications.

  1. Adaptive Multi-Lag for Synthetic Aperture Vector Flow Imaging

    DEFF Research Database (Denmark)

    Villagómez Hoyos, Carlos Armando; Stuart, Matthias Bo; Jensen, Jørgen Arendt

    2014-01-01

    The range of detectable velocities in ultrasound flow imaging is linked to the user selection of pulse repetiti on frequency. Whenever a region with large differences in velo city magnitude is visualized, a trade-off has to be made. This work suggests an adaptive spatio-temporaly independent, m...

  2. Increasing the Dynamic Range of Synthetic Aperture Vector Flow Imaging

    DEFF Research Database (Denmark)

    Villagómez Hoyos, Carlos Armando; Stuart, Matthias Bo; Jensen, Jørgen Arendt

    2014-01-01

    In current ultrasound systems the dynamic range of detectable velocities is susceptible to the selected pulse repetition frequency, thus limiting the dynamic range of flow mapping. To establish the feasibility of extending the range of detectable velocities towards low velocity vessels, results...... standard deviations are 1.59% and 6.12%, respectively. The presented method can improve the estimates by synthesizing a lower pulse repetition frequency, thereby increasing the dynamic range of the vector velocity imaging....

  3. Synthetic Aperture Sequential Beamforming and other Beamforming Techniques in Ultrasound Imaging

    DEFF Research Database (Denmark)

    Kortbek, Jacob

    This thesis consists of various subjects and applications within beamforming in general, and subjects within synthetic aperture focusing. An insight into the software architecture and beamformer design principles of a software beamformation toolbox is given. Some of the many considerations......, and up-sampling and FIR filtering. Directional beamforming for angle estimation of the velocity vector has been investigated using simulations and measurements. Using the measurements more than 96% valid estimates were produced for the flow angles q = {60±,75±,90±} and with a bias below 2± and a standard...... deviation below 5±. The two synthetic aperture imaging techniques described in this thesis are both candidates for a realistic implementation in a commercial scanner. In one technique synthetic aperture focusing (SAF) is applied to 2-dimensional imaging with a single rotating mechanically focused concave...

  4. An iterative synthetic aperture imaging algorithm with correction of diffraction effects.

    Science.gov (United States)

    Wennerström, Erik; Stepinski, Tadeusz; Olofsson, Tomas

    2006-05-01

    In this paper we present an iterative version of the synthetic aperture imaging algorithm extended synthetic aperture technique (ESAFT) proposed recently. The algorithm is based on a linear model that accounts for the distortions effects of an imaging system used for acquisition of ultrasonic data. Improved resolution (both lateral and temporal) in the reconstructed image is obtained as a result of minimizing the reconstruction mean square error. In this work, the minimization is extended to parameters that characterize expected amplitudes of each image element in the area of interest. An iterative optimization scheme is proposed, which in each step performs minimization of the reconstruction error based on the parameter matrix found in the previous step. Comparing to ESAFT, the proposed approach yields a significant improvement in resolution and a high degree of robustness with regard to initial choice of the parameter matrix. Performance of the proposed algorithm is evaluated using both real and simulated ultrasonic data.

  5. Non-linear Imaging using an Experimental Synthetic Aperture Real Time Ultrasound Scanner

    DEFF Research Database (Denmark)

    Rasmussen, Joachim; Du, Yigang; Jensen, Jørgen Arendt

    2011-01-01

    This paper presents the first non-linear B-mode image of a wire phantom using pulse inversion attained via an experimental synthetic aperture real-time ultrasound scanner (SARUS). The purpose of this study is to implement and validate non-linear imaging on SARUS for the further development of new...... non-linear techniques. This study presents non-linear and linear B-mode images attained via SARUS and an existing ultrasound system as well as a Field II simulation. The non-linear image shows an improved spatial resolution and lower full width half max and -20 dB resolution values compared to linear...

  6. Segmentation of synthetic aperture radar image using multiscale information measure-based spectral clustering

    Institute of Scientific and Technical Information of China (English)

    Haixia Xu; Zheng Tian; Mingtao Ding

    2008-01-01

    @@ A multiscale information measure (MIM), calculable from per-pixel wavelet coefficients, but relying on global statistics of synthetic aperture radar (SAR) image, is proposed. It fully exploits the variations in speckle pattern when the image resolution varies from course to fine, thus it can capture the intrinsic texture of the scene backscatter and the texture due to speckle simultaneously. Graph spectral segmentation methods based on MIM and the usual similarity measure are carried out on two real SAR images.Experimental results show that MIM can characterize texture information of SAR image more effectively than the commonly used similarity measure.

  7. Comparison between different encoding schemes for synthetic aperture imaging

    DEFF Research Database (Denmark)

    Nikolov, Svetoslav; Jensen, Jørgen Arendt

    2002-01-01

    have solved the first problem by building a scanner capable of acquiring data using STAU in real-time. The SNR is increased by using encoded signals, which make it possible to send more energy in the body, while reserving the spatial and contrast resolution. The performance of temporal, spatial...... and spatio-temporal encoding was investigated. Experiments on wire phantom in water were carried out to quantify the gain from the different encodings. The gain in SNR using an FM modulated pulse is 12 dB. The penetration depth of the images was studied using tissue mimicking phantom with frequency dependent...... influence the performance of the STAU....

  8. Preliminary Experimental Verification of Synthetic Aperture Flow Imaging Using a Dual Stage Beamformer Approach

    DEFF Research Database (Denmark)

    Li, Ye; Jensen, Jørgen Arendt

    2011-01-01

    A dual stage beamformer method for synthetic aperture flow imaging has been developed. The motivation is to increase the frame rate and still maintain a beamforming quality sufficient for flow estimation that is possible to implement in a commercial scanner. With the new method high resolution im...

  9. Synthetic Aperture Focusing Applied to Imaging Using a Rotating Single Element Transducer

    DEFF Research Database (Denmark)

    Kortbek, Jacob; Jensen, Jørgen Arendt; Gammelmark, Kim Løkke

    2007-01-01

    This paper applies the concept of virtual sources and mono-static synthetic aperture focusing (SAF) to 2-dimensional imaging with a single rotating mechanically focused concave element with the objective of improving lateral resolution and signal-to-noise ratio (SNR). The geometrical focal point ...

  10. Image of Synthetic Biology and Nanotechnology: A Survey among University Students

    Directory of Open Access Journals (Sweden)

    Christian Ineichen

    2017-09-01

    Full Text Available This study explores the image of synthetic biology and nanotechnology in comparison to agricultural biotechnology and communication technology by examining spontaneous associations with, and deliberate evaluations of, these technologies by university students. Data were collected through a self-completion online questionnaire by students from two universities in Switzerland. The survey aimed to capture implicit associations, explicit harm-benefit evaluations and views on regulation. The data suggest overall positive associations with emerging technologies. While positive associations were most pronounced for nanotechnology, agricultural biotechnology was attributed with the least favorable associations. In contrast to its positive result in the association task, respondents attributed a high harm potential for nanotechnology. Associations attributed to synthetic biology were demonstrated to be more positive than for agricultural biotechnology, however, not as favorable as for nanotechnology. Contrary to the evaluations of nanotechnology, the benefit-examples of synthetic biology were evaluated particularly positively. Accordingly, the investigated technologies enjoy different esteem, with synthetic biology and nanotechnology both showing a more “exciting” image. Even though, the image of nanotechnology was demonstrated to be more pronounced it was also more heterogeneous across tasks while agricultural biotechnology remains contested. For all technologies, the predominant spontaneous concerns pertain to risks rather than an immoral nature inherent to these technologies. Our data suggest that harm-benefit analyses reveal only one aspect of the attitude toward emerging technologies. Survey questions addressing spontaneous associations with these technologies are a valuable addition for our picture of the image of emerging technologies.

  11. Implementation of Tissue Harmonic Synthetic Aperture Imaging on a Commercial Ultrasound System

    DEFF Research Database (Denmark)

    Rasmussen, Joachim; Hemmsen, Martin Christian; Madsen, Signe Sloth

    2012-01-01

    This paper presents an imaging technique for synthetic aperture (SAI) tissue harmonic imaging (THI) on a commercial ultrasound system. Synthetic aperture sequential beamforming (SASB) is combined with a pulse inversion (PI) technique on a commercial BK 2202 UltraView system. An interleaved scan...... sequence that performs dynamic receive focused (DRF) imaging and SASB, both using PI, is implemented. From each acquisition four images can be created: DRF image, SASB image, tissue harmonic DRF image (DRF-THI), and tissue harmonic SASB image (SASB-THI). For SASB imaging, a fixed transmit and receive focus...... at 80 mm and an F# of 3 is applied. For DRF imaging, default scanner settings are used, which are a focus at 85 mm and F# of 5.7 in transmit and a dynamic receive aperture with an F# of 0.8. In all cases a 2.14 MHz one-and-ahalf cycle excitation transmit waveform is used. A BK 8820e 192 element convex...

  12. Electrochemical detection of synthetic DNA and native 16S rRNA fragments on a microarray using a biotinylated intercalator as coupling site for an enzyme label.

    Science.gov (United States)

    Zimdars, Andreas; Gebala, Magdalena; Hartwich, Gerhard; Neugebauer, Sebastian; Schuhmann, Wolfgang

    2015-10-01

    The direct electrochemical detection of synthetic DNA and native 16S rRNA fragments isolated from Escherichia coli is described. Oligonucleotides are detected via selective post-labeling of double stranded DNA and DNA-RNA duplexes with a biotinylated intercalator that enables high-specific binding of a streptavidin/alkaline phosphatase conjugate. The alkaline phosphatase catalyzes formation of p-aminophenol that is subsequently oxidized at the underlying gold electrode and hence enables the detection of complementary hybridization of the DNA capture strands due to the enzymatic signal amplification. The hybridization assay was performed on microarrays consisting of 32 individually addressable gold microelectrodes. Synthetic DNA strands with sequences representing six different pathogens which are important for the diagnosis of urinary tract infections could be detected at concentrations of 60 nM. Native 16S rRNA isolated from the different pathogens could be detected at a concentration of 30 fM. Optimization of the sensing surface is described and influences on the assay performance are discussed. Copyright © 2015 Elsevier B.V. All rights reserved.

  13. 300 GHz imaging with 8 meter stand-off distance and one-dimensional synthetic image reconstruction

    DEFF Research Database (Denmark)

    Keil, Andreas; Quast, Holger; Loeffler, Torsten

    2011-01-01

    of mirrors with effective aperture of 0.5 × 0.5 meter. Information about range and reflectivity of the object are obtained using an active FMCW (frequency modulated continuous wave) radar operation principle. Data acquisition time for one line is as short as 1 ms. Synthetic image reconstruction is achieved...

  14. Bistatic synthetic aperture radar imaging using ultraNarrowband continuous waveforms.

    Science.gov (United States)

    Wang, Ling; Yazici, Birsen

    2012-08-01

    We consider synthetic aperture radar (SAR) imaging using ultra-narrowband continuous waveforms (CW). Due to the high Doppler resolution of CW signals, we refer to this imaging modality as Doppler Synthetic Aperture Radar (DSAR). We present a novel model and an image formation method for the bistatic DSAR for arbitrary imaging geometries. Our bistatic DSAR model is formed by correlating the translated version of the received signal with a scaled or frequencyshifted version of the transmitted CW signal over a finite time window. High frequency analysis of the resulting model shows that the correlated signal is the projections of the scene reflectivity onto the bistatic iso-Doppler curves. We next use microlocal techniques to develop a filtered-backprojection (FBP) type image reconstruction method. The FBP inversion results in backprojection of the correlated signal onto the bistatic iso- Doppler curves as opposed to the bistatic iso-range curves, performed in the traditional wideband SAR imaging. We show that our method takes advantage of the velocity, as well as the acceleration of the antennas in certain directions to form a high resolution SAR image. Our bistatic DSAR imaging method is applicable for arbitrary flight trajectories, nonflat topography, and can accommodate system related parameters. We present resolution analysis and extensive numerical experiments to demonstrate the performance of our imaging method.

  15. Semi-synthesis of biologically active nisin hybrids composed of the native lanthionine ABC-fragment and a cross-stapled synthetic DE-fragment.

    Science.gov (United States)

    Slootweg, Jack C; Peters, Nienke; Quarles van Ufford, H Linda C; Breukink, Eefjan; Liskamp, Rob M J; Rijkers, Dirk T S

    2014-10-01

    The antimicrobial peptide nisin is a promising template for designing novel peptide-based antibiotics to improve its drug-like properties. First steps in that direction represent the synthesis of hybrid nisin derivatives that contain a native nisin ABC-part and synthesized cross-stapled DE-ring fragments and are described here. The biological activity of the newly synthesized nisin derivatives was evaluated in order to compare the bioactivity of the synthetic DE-ring containing mimic and native lanthionine-bridged DE-ring containing nisin. The native nisin ABC-ring system was obtained via chymotrypsin digestion of full-length nisin, and was subsequently functionalized at the C-terminal carboxylate with two different amino alkyne moieties. Next, nisin hybrids were successfully prepared using Cu(I)-catalyzed azide alkyne cycloaddition 'click' chemistry by chemo-selective ligation of the ABC-alkyne with the N-terminal azido functionalized dicarba-DE ring mimic. The newly synthesized compounds were active as potent lipid II binders and retained antimicrobial activity in a growth inhibition assay. However, pore formation was not observed, possibly either due to the different character of the 'staples' as compared to the parent sulfides, or due to the triazole moiety as a sub-optimal amide bond isostere.

  16. A realistic phantom for validating MRI-based synthetic CT images of the human skull.

    Science.gov (United States)

    Soliman, Abraam S; Burns, Levi; Owrangi, Amir; Lee, Young; Song, William Y; Stanisz, Greg; Chugh, Brige P

    2017-06-23

    To introduce a new realistic human skull phantom for the validation of synthetic CT images of cortical bone from ultra-short echo-time (UTE) sequences. A human skull of an adult female was utilized as a realistic representation of skull cortical bone. The skull was stabilized in a special acrylic container and was filled with contrast agents that have T1 and T2 relaxation times similar to human brain. The phantom was MR scanned at 3T with UTE and T2 -weighted sequences, followed by CT. A clustering approach was developed to extract the cortical bone signal from MR images. T2∗ maps of the skull were calculated. Synthetic CT images of the bone were compared to cortical bone signal extracted from CT images and confounding factors, such as registration errors, were analyzed. Dice similarity coefficient (DSC) of UTE-detected cortical bone was 0.84 and gradually decreased with decreasing number of spokes. DSC did not significantly depend on echo-time. Registration errors were found to be significant confounding factors, with 25% decrease in DSC for consistent 2 mm error at each axis. This work introduced a new realistic human skull phantom, specifically for the evaluation and analysis of synthetic CT images of cortical bone. © 2017 American Association of Physicists in Medicine.

  17. Submicron hard X-ray fluorescence imaging of synthetic elements

    Energy Technology Data Exchange (ETDEWEB)

    Jensen, Mark P., E-mail: mjensen@anl.gov [Chemical Sciences and Engineering Division, Argonne National Laboratory, Argonne, IL 60439 (United States); Aryal, Baikuntha P. [Chemical Sciences and Engineering Division, Argonne National Laboratory, Argonne, IL 60439 (United States); Department of Chemistry, University of Chicago, Chicago, IL 60637 (United States); Gorman-Lewis, Drew [Chemical Sciences and Engineering Division, Argonne National Laboratory, Argonne, IL 60439 (United States); Paunesku, Tatjana [Department of Radiation Oncology, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611 (United States); Department of Radiology, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611 (United States); Lai, Barry; Vogt, Stefan [X-ray Science Division, Advanced Photon Source, Argonne National Laboratory, Argonne, IL 60439 (United States); Woloschak, Gayle E. [Department of Radiation Oncology, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611 (United States); Department of Radiology, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611 (United States)

    2012-04-13

    Highlights: Black-Right-Pointing-Pointer Actinide elements are mapped with L-edge X-rays and better than 400 nm resolution. Black-Right-Pointing-Pointer A typical detection limit was 2.9 Multiplication-Sign 10{sup -20} moles Pu {mu}m{sup -2}. Black-Right-Pointing-Pointer XANES measurements provide chemical information in 0.1 {mu}m{sup 2} spots. Black-Right-Pointing-Pointer Selection of materials for encapsulation is important for avoiding interferences. - Abstract: Synchrotron-based X-ray fluorescence microscopy (XFM) using hard X-rays focused into sub-micron spots is a powerful technique for elemental quantification and mapping, as well as microspectroscopic measurements such as {mu}-XANES (X-ray absorption near edge structure). We have used XFM to image and simultaneously quantify the transuranic element plutonium at the L{sub 3} or L{sub 2}-edge as well as Th and lighter biologically essential elements in individual rat pheochromocytoma (PC12) cells after exposure to the long-lived plutonium isotope {sup 242}Pu. Elemental maps demonstrate that plutonium localizes principally in the cytoplasm of the cells and avoids the cell nucleus, which is marked by the highest concentrations of phosphorus and zinc, under the conditions of our experiments. The minimum detection limit under typical acquisition conditions with an incident X-ray energy of 18 keV for an average 202 {mu}m{sup 2} cell is 1.4 fg Pu or 2.9 Multiplication-Sign 10{sup -20} moles Pu {mu}m{sup -2}, which is similar to the detection limit of K-edge XFM of transition metals at 10 keV. Copper electron microscopy grids were used to avoid interference from gold X-ray emissions, but traces of strontium present in naturally occurring calcium can still interfere with plutonium detection using its L{sub {alpha}} X-ray emission.

  18. Comparison of 3D Synthetic Aperture Imaging and Explososcan using Phantom Measurements

    DEFF Research Database (Denmark)

    Rasmussen, Morten Fischer; Férin, Guillaume; Dufait, Rémi

    2012-01-01

    In this paper, initial 3D ultrasound measurements from a 1024 channel system are presented. Measurements of 3D Synthetic aperture imaging (SAI) and Explososcan are presented and compared. Explososcan is the ’gold standard’ for real-time 3D medical ultrasound imaging. SAI is compared to Explososcan...... by using tissue and wire phantom measurements. The measurements are carried out using a 1024 element 2D transducer and the 1024 channel experimental ultrasound scanner SARUS. To make a fair comparison, the two imaging techniques use the same number of active channels, the same number of emissions per frame...

  19. Survey of Study on Internal Waves Detection in Synthetic Aperture Radar Image

    Directory of Open Access Journals (Sweden)

    Chong Jin-song

    2013-12-01

    Full Text Available In recent years, Internal Waves (IWs detection in Synthetic Aperture Radar (SAR image has received considerable attentions in the area of marine remote sensing and has already become one of the most important marine applications of SAR. Typical research results at home and abroad are reviewed. Three areas of researches are introduced and summarized, including parameter inversion method of IWs, the effect of different SAR parameter and wind field conditions on IWs imaging, the 2-dimentional SAR imaging simulation of IWs.

  20. In-Vivo Synthetic Aperture and Plane Wave High Frame Rate Cardiac Imaging

    DEFF Research Database (Denmark)

    Stuart, Matthias Bo; Jensen, Jonas; Brandt, Andreas Hjelm;

    2014-01-01

    A comparison of synthetic aperture imaging using spherical and plane waves with low number of emission events is presented. For both wave types, a 90 degree sector is insonified using 15 emission events giving a frame rate of 200 frames per second. Field II simulations of point targets show simil.......43 for spherical and 0.70 for plane waves. All measures are well within FDA limits for cardiac imaging. In-vivo images of the heart of a healthy 28-year old volunteer are shown....

  1. SIMULATION STUDY OF IMAGING OF UNDERWATER BOTTOM TOPOGRAPHY BY SYNTHETIC APERTURE RADAR

    Institute of Scientific and Technical Information of China (English)

    2001-01-01

    Interaction between current and underwater bottom topography modulates roughness of the sea surface, which in turn yields variation of the radar scattering echo. By using the mechanism, this paper presents a simulation model for Synthetic Aperture Radar (SAR) imaging of underwater bottom topography. The numerical simulations experiments were made using the Princeton Ocean Model (POM) and analytical expression theory of SAR Image in Mischief sea area. It is concluded that the SAR image is better visual when water depth of underwater bottom topography is shallow or gradient of underwater bottom topography is high.

  2. Directional synthetic aperture flow imaging using a dual stage beamformer approach

    DEFF Research Database (Denmark)

    Li, Ye; Jensen, Jørgen Arendt

    2011-01-01

    A new method for directional synthetic aperture flow imaging using a dual stage beamformer approach is presented. The velocity estimation is angle independent and the amount of calculations is reduced compared to full synthetic aperture, but still maintains all the advantages at the same time....... In the second stage, focal points are considered as virtual sources and data is beamformed along the flow direction. Then the velocities are estimated by finding the spatial shift between two signals. In the experimental measurements the angle between the transmit beam and flow vessel was 70 and a laminar flow...... with a parabolic profile was generated by a flow rig. The flow with a peak velocity of 0.1 m/s was sampled at a pulse repetition frequency of 4 kHz. The signals were transmitted and received by the experimental scanner SARUS (Synthetic Aperture Realtime Ultrasound System). A relative standard deviation of 2...

  3. Object Hierarchy-based Supervised Characterisation ofSynthetic Aperture Radar Sensor Images

    Directory of Open Access Journals (Sweden)

    Ish Rishabh

    2008-01-01

    Full Text Available A method of supervised characterisation of synthetic aperture radar (SAR satellite imageshas been discussed in which simple object shape features of satellite images have been usedto classify and describe the terrain types. This scheme is based on a multilevel approach inwhich objects of interest are first segmented out from the image and subsequently characterisedbased on their shape features. Once all objects have been characterised, the entire image canbe characterised. Emphasis has been laid on the hierarchical information extraction from theimage which enables greater flexibility in characterising the image and is not restricted to mereclassification. The paper also describes a method for giving relative importance among features,i.e., to give more weights to those features that are better than others in distinguishing betweencompeting classes. A method of comparing two SAR sensor images based on terrain elementspresent in the images has also been described here.

  4. Synthetic aperture radar image processing techniques for damage detection of FRP-concrete systems

    Science.gov (United States)

    Yu, Tzuyang

    2017-04-01

    Electromagnetic imaging enables researchers and engineers to assess the surface and subsurface condition of concrete structures using radar and microwave sensors. Among existing radar imaging methods, synthetic aperture radar (SAR) imaging offers flexible resolution for various purposes in condition assessment. In this paper, two novel SAR image processing techniques are reported for the subsurface condition assessment of FRP(fiber reinforced polymer)-strengthened concrete systems; mathematical morphology (MM) and the K-R-I transform. Glass FRP (GFRP) and carbon CFRP (CFRP) strengthened concrete cylinders are used as examples. From our experimental results, it is found that both techniques are capable of quantifying SAR images for condition assessment. It is also found that Euler's number and the coefficient of correlation of K-R-I curves of SAR images can be used for monitoring subsurface changes in FRP-concrete systems.

  5. Pathology of a H5N1, highly pathogenic avian influenza virus, in two Indian native chicken breeds and a synthetic broiler line.

    Science.gov (United States)

    Suba, S; Nagarajan, S; Saxena, V K; Kumar, M; Vanamayya, P R; Rajukumar, K; Gowthaman, V; Jain, V; Singh, D P; Dubey, S C

    2015-04-01

    In this study, susceptibility to H5N1 virus infection was studied in two Indian native chicken breeds viz. Kadaknath and Aseel (Peela) and an Indian synthetic broiler strain (Synthetic dam line (SDL-IC). Fifty birds from each genetic group were infected intra-nasally with 1000 EID50 of a highly pathogenic avian influenza virus (HPAIV) strain A/chicken/Navapur/India/7972/ 06 (H5N1) and observed for a period of 10 days. Significant differences in severity of clinical signs, gross lesions and time for onset of symptoms were observed. The overall severity of clinical signs and gross lesions was less in SDL-IC broilers as compared to the other two genetic groups. The mortality percentages were 100, 98 and 92% with Mean Death Time (MDT) of 3.12, 5.92 and 6.96 days, respectively for the two native breeds Kadaknath and Aseel (Peela), the and SDL-IC broiler strain. Comparison of histological lesions revealed differences in disease progression among the genetic groups. Vascular lesions such as disseminated intravascular coagulopathy (DIC) were predominant on 3 days post infection (dpi) in Kadaknath, and on 5 and 6 dpi in Aseel (Peela) and SDL-IC broiler. The mean log2 HA titres of the re-isolated virus from various organs of H5N1 AIV infected birds of the three genetic groups ranged from 2.32 (lung, trachea and bursa) to 5.04 (spleen) in Kadaknath; 2.32 (lung) to 6.68 (brain) in Aseel (Peela); and 2.06 (liver) to 7.01 (lungs and kidney) in SDL-IC broiler. These results suggest that the susceptibility to H5N1 highly pathogenic avian influenza virus infection differed among the three breeds; Kadaknath being highest followed by Aseel (Peela) and synthetic SDL-IC broiler. This is possibly the first report on the differences in the susceptibility of the India native breeds to H5N1 virus infection and its severity.

  6. Research of inverse synthetic aperture imaging lidar based on filtered back-projection tomography technique

    Science.gov (United States)

    Liu, Zhi-chao; Yang, Jin-hua

    2014-07-01

    In order to obtain clear two-dimensional image under the conditions without using heterodyne interferometry by inverse synthetic aperture lidar(ISAL), designed imaging algorithms based on filtered back projection tomography technique, and the target "A" was reconstructed with simulation algorithm by the system in the turntable model. Analyzed the working process of ISAL, and the function of the reconstructed image was given. Detail analysis of the physical meaning of the various parameters in the process of echo data, and its parameters affect the reconstructed image. The image in test area was reconstructed by the one-dimensional distance information with filtered back projection tomography technique. When the measured target rotated, the sum of the echo light intensity at the same distance was constituted by the different position of the measured target. When the total amount collected is large enough, multiple equations can be solved change. Filtered back-projection image of the ideal image is obtained through MATLAB simulation, and analyzed that the angle intervals affected the reconstruction of image. The ratio of the intensity of echo light and loss light affected the reconstruction of image was analyzed. Simulation results show that, when the sampling angle is smaller, the resolution of the reconstructed image of measured target is higher. And the ratio of the intensity of echo light and loss light is greater, the resolution of the reconstructed image of measured target is higher. In conclusion after some data processing, the reconstructed image basically meets be effective identification requirements.

  7. A new approach to compensate the geometric distortion in the synthetic aperture ultrasonic imaging system.

    Science.gov (United States)

    He, Xiaonian; Liu, Weixiang; Chen, Siping; Qin, Zhengdi

    2015-01-01

    In the field of ultrasonic imaging technology, the problem of geometric distortion is often encountered, especially in the ultrasonic near-field. In this study, a new approach is proposed to compensate for geometric distortion in the synthetic aperture ultrasonic imaging system. This approach is based on the synthetic aperture ultrasonic holographic B-scan (UHB) imaging system, which is a combination of ultrasonic holography based on the backward propagation principle and the conventional B-scan technique. To solve the geometric distortion problem, the operation of the spatial compression and resampling in the frequency domain are introduced. The main advantage of the approach is that the real holographic value can be calculated without distortion by using the spatial interpolation function after the spatial frequency compression. After the compensation for geometric distortion is performed, the synthetic aperture technique based on the backward propagation principle is then applied in the process of the two-dimensional numerical imaging reconstruction. Both the simulation and measurement experiment show that the approach is promising. The geometric distortion that is dependent on the wave front angle can be effectively compensated. The spatial resolution is practically uniform throughout the depth range and close to the theoretical limit in the experiments.

  8. A relaxed fusion of information from real and synthetic images to predict complex behavior

    Science.gov (United States)

    Lyons, Damian M.; Benjamin, D. Paul

    2011-05-01

    An important component of cognitive robotics is the ability to mentally simulate physical processes and to compare the expected results with the information reported by a robot's sensors. In previous work, we have proposed an approach that integrates a 3D game-engine simulation into the robot control architecture. A key part of that architecture is the Match-Mediated Difference (MMD) operation, an approach to fusing sensory data and synthetic predictions at the image level. The MMD operation insists that simulated and predicted scenes are similar in terms of the appearance of the objects in the scene. This is an overly restrictive constraint on the simulation since parts of the predicted scene may not have been previously viewed by the robot. In this paper we propose an extended MMD operation that relaxes the constraint and allows the real and synthetic scenes to differ in some features but not in (selected) other features. Image difference operations that allow a real image and synthetic image generated from an arbitrarily colored graphical model of a scene to be compared. Scenes with the same content show a zero difference. Scenes with varying foreground objects can be controlled to compare the color, size and shape of the foreground.

  9. Computational Complexity Reduction of Synthetic-aperture Focus in Ultrasound Imaging Using Frequency-domain Reconstruction.

    Science.gov (United States)

    Moghimirad, Elahe; Mahloojifar, Ali; Mohammadzadeh Asl, Babak

    2016-05-01

    A new frequency-domain implementation of a synthetic aperture focusing technique is presented in the paper. The concept is based on synthetic aperture radar (SAR) and sonar that is a developed version of the convolution model in the frequency domain. Compared with conventional line-by-line imaging, synthetic aperture imaging has a better resolution and contrast at the cost of more computational load. To overcome this problem, point-by-point reconstruction methods have been replaced by block-processing algorithms in radar and sonar; however, these techniques are relatively unknown in medical imaging. In this paper, we extended one of these methods called wavenumber to medical ultrasound imaging using a simple model of synthetic aperture focus. The model, derived here for monostatic mode, can be generalized to multistatic as well. The method consists of 4 steps: a 2D fast Fourier transform of the data, frequency shift of the data to baseband, interpolation to convert polar coordinates to rectangular ones, and returning the data to the spatial-domain using a 2D inverse Fourier transform. We have also used chirp pulse excitation followed by matched filtering and spotlighting algorithm to compensate the effect of differences in parameters between radar and medical imaging. Computational complexities of the two methods, wavenumber and delay-and-sum (DAS), have been calculated. Field II simulated point data have been used to evaluate the results in terms of resolution and contrast. Evaluations with simulated data show that for typical phantoms, reconstruction by the wavenumber algorithm is almost 20 times faster than classical DAS while retaining the resolution. © The Author(s) 2015.

  10. Feasibility analysis of high resolution tissue image registration using 3-D synthetic data

    Directory of Open Access Journals (Sweden)

    Yachna Sharma

    2011-01-01

    Full Text Available Background: Registration of high-resolution tissue images is a critical step in the 3D analysis of protein expression. Because the distance between images (~4-5μm thickness of a tissue section is nearly the size of the objects of interest (~10-20μm cancer cell nucleus, a given object is often not present in both of two adjacent images. Without consistent correspondence of objects between images, registration becomes a difficult task. This work assesses the feasibility of current registration techniques for such images. Methods: We generated high resolution synthetic 3-D image data sets emulating the constraints in real data. We applied multiple registration methods to the synthetic image data sets and assessed the registration performance of three techniques (i.e., mutual information (MI, kernel density estimate (KDE method [1], and principal component analysis (PCA at various slice thicknesses (with increments of 1μm in order to quantify the limitations of each method. Results: Our analysis shows that PCA, when combined with the KDE method based on nuclei centers, aligns images corresponding to 5μm thick sections with acceptable accuracy. We also note that registration error increases rapidly with increasing distance between images, and that the choice of feature points which are conserved between slices improves performance. Conclusions: We used simulation to help select appropriate features and methods for image registration by estimating best-case-scenario errors for given data constraints in histological images. The results of this study suggest that much of the difficulty of stained tissue registration can be reduced to the problem of accurately identifying feature points, such as the center of nuclei.

  11. Investigation of synthetic aperture methods in ultrasound surface imaging using elementary surface types.

    Science.gov (United States)

    Kerr, W; Pierce, S G; Rowe, P

    2016-12-01

    Synthetic aperture imaging methods have been employed widely in recent research in non-destructive testing (NDT), but uptake has been more limited in medical ultrasound imaging. Typically offering superior focussing power over more traditional phased array methods, these techniques have been employed in NDT applications to locate and characterise small defects within large samples, but have rarely been used to image surfaces. A desire to ultimately employ ultrasonic surface imaging for bone surface geometry measurement prior to surgical intervention motivates this research, and results are presented for initial laboratory trials of a surface reconstruction technique based on global thresholding of ultrasonic 3D point cloud data. In this study, representative geometry artefacts were imaged in the laboratory using two synthetic aperture techniques; the Total Focusing Method (TFM) and the Synthetic Aperture Focusing Technique (SAFT) employing full and narrow synthetic apertures, respectively. Three high precision metallic samples of known geometries (cuboid, sphere and cylinder) which featured a range of elementary surface primitives were imaged using a 5MHz, 128 element 1D phased array employing both SAFT and TFM approaches. The array was manipulated around the samples using a precision robotic positioning system, allowing for repeatable ultrasound derived 3D surface point clouds to be created. A global thresholding technique was then developed that allowed the extraction of the surface profiles, and these were compared with the known geometry samples to provide a quantitative measure of error of 3D surface reconstruction. The mean errors achieved with optimised SAFT imaging for the cuboidal, spherical and cylindrical samples were 1.3mm, 2.9mm and 2.0mm respectively, while those for TFM imaging were 3.7mm, 3.0mm and 3.1mm, respectively. These results were contrary to expectations given the higher information content associated with the TFM images. However, it was

  12. Overexpression of the Synthetic Chimeric Native-T-phylloplanin-GFP Genes Optimized for Monocot and Dicot Plants Renders Enhanced Resistance to Blue Mold Disease in Tobacco (N. tabacum L.

    Directory of Open Access Journals (Sweden)

    Dipak K. Sahoo

    2014-01-01

    Full Text Available To enhance the natural plant resistance and to evaluate the antimicrobial properties of phylloplanin against blue mold, we have expressed a synthetic chimeric native-phylloplanin-GFP protein fusion in transgenic Nicotiana tabacum cv. KY14, a cultivar that is highly susceptible to infection by Peronospora tabacina. The coding sequence of the tobacco phylloplanin gene along with its native signal peptide was fused with GFP at the carboxy terminus. The synthetic chimeric gene (native-phylloplanin-GFP was placed between the modified Mirabilis mosaic virus full-length transcript promoter with duplicated enhancer domains and the terminator sequence from the rbcSE9 gene. The chimeric gene, expressed in transgenic tobacco, was stably inherited in successive plant generations as shown by molecular characterization, GFP quantification, and confocal fluorescent microscopy. Transgenic plants were morphologically similar to wild-type plants and showed no deleterious effects due to transgene expression. Blue mold-sensitivity assays of tobacco lines were performed by applying P. tabacina sporangia to the upper leaf surface. Transgenic lines expressing the fused synthetic native-phyllopanin-GFP gene in the leaf apoplast showed resistance to infection. Our results demonstrate that in vivo expression of a synthetic fused native-phylloplanin-GFP gene in plants can potentially achieve natural protection against microbial plant pathogens, including P. tabacina in tobacco.

  13. Oral and parenteral immunization with synthetic retro-inverso peptides induce antibodies that cross-react with native peptides and parent antigens.

    Science.gov (United States)

    Fischer, Peter; Comis, Alfio; Tyler, Margaret; Howden, Merlin

    2007-06-01

    The objective of this study was to determine whether certain retro-inverso peptides have the potential to act as synthetic vaccines in mice, when immunized by injection or orally. Immunization of mice parenterally with conjugates of three such retro-inverso peptides and orally with the unconjugated peptides elicited generally high titres of anti-peptide antibodies. Antibodies against the same three peptides cross-reacted by binding strongly in ELISA to the native peptides and vice versa, regardless of the mode of immunization. Antibodies against a retro-inverso diphtheria peptide also reacted strongly with diphtheria toxin. Seven of 8 mice, immunized by injection of the conjugate of a retro-inverso derivative of robustoxin [a lethal spider (Atrax robustus) venom toxin] were protected from challenge involving injection with twice the minimum lethal dose of A. robustus venom containing the toxin.

  14. Feature-enhanced synthetic aperture radar image formation based on nonquadratic regularization.

    Science.gov (United States)

    Cetin, M; Karl, W C

    2001-01-01

    We develop a method for the formation of spotlight-mode synthetic aperture radar (SAR) images with enhanced features. The approach is based on a regularized reconstruction of the scattering field which combines a tomographic model of the SAR observation process with prior information regarding the nature of the features of interest. Compared to conventional SAR techniques, the method we propose produces images with increased resolution, reduced sidelobes, reduced speckle and easier-to-segment regions. Our technique effectively deals with the complex-valued, random-phase nature of the underlying SAR reflectivities. An efficient and robust numerical solution is achieved through extensions of half-quadratic regularization methods to the complex-valued SAR problem. We demonstrate the performance of the method on synthetic and real SAR scenes.

  15. Clinical evaluation of synthetic aperture harmonic imaging for scanning focal malignant liver lesions

    DEFF Research Database (Denmark)

    Brandt, Andreas Hjelm; Hemmsen, Martin Christian; Hansen, Peter Møller

    2015-01-01

    The purpose of the study was to perform a clinical comparison of synthetic aperture sequential beamformingtissue harmonic imaging (SASB-THI) sequences with a conventional imaging technique, dynamic receivefocusing with THI (DRF-THI). Both techniques used pulse inversion and were recorded...... interleaved using a commercialultrasound system (UltraView 800, BK Medical, Herlev, Denmark). Thirty-one patients with malignantfocal liver lesions (confirmed by biopsy or computed tomography/magnetic resonance) were scanned. Detectionof malignant focal liver lesions and preference of image quality were...... evaluated blinded off-line by eight radiologists.In total, 2,032 evaluations of 127 image sequences were completed. The sensitivity (77% SASB-THI, 76%DRF-THI, p 5 0.54) and specificity (71% SASB-THI, 72% DRF-THI, p 5 0.67) of detection of liver lesions andthe evaluation of image quality (p 5 0.63) did...

  16. Clinical evaluation of Synthetic Aperture Sequential Beamforming and Tissue Harmonic Imaging

    DEFF Research Database (Denmark)

    Brandt, Andreas Hjelm; Hemmsen, Martin Christian; Hansen, Peter Møller

    2014-01-01

    This study determines if the data reduction achieved by the combination Synthetic Aperture Sequential Beamforming (SASB) and Tissue Harmonic Imaging (THI) affects image quality. SASB-THI was evaluated against the combination of Dynamic Received Focusing and Tissue Harmonic Imaging (DRF-THI). A BK...... liver pathology were scanned to set a clinical condition, where ultrasonography is often performed. A total of 114 sequences were recorded and evaluated by five radiologists. The evaluators were blinded to the imaging technique, and each sequence was shown twice with different left-right positioning......, resulting in 1140 evaluations. The program Image Quality Assessment Program (IQap) and a Visual Analog Scale (VAS) were applied for the evaluation. The scale ranged from -50 to 50, where positive values favored SASB-THI. SASB-THI and DRF-THI were evaluated alike in 49% of the evaluations, 28% favored SASB...

  17. Multibeam single frequency synthetic aperture radar processor for imaging separate range swaths

    Science.gov (United States)

    Jain, A. (Inventor)

    1982-01-01

    A single-frequency multibeam synthetic aperture radar for large swath imaging is disclosed. Each beam illuminates a separate ""footprint'' (i.e., range and azimuth interval). The distinct azimuth intervals for the separate beams produce a distinct Doppler frequency spectrum for each beam. After range correlation of raw data, an optical processor develops image data for the different beams by spatially separating the beams to place each beam of different Doppler frequency spectrum in a different location in the frequency plane as well as the imaging plane of the optical processor. Selection of a beam for imaging may be made in the frequency plane by adjusting the position of an aperture, or in the image plane by adjusting the position of a slit. The raw data may also be processed in digital form in an analogous manner.

  18. Brute Force Matching Between Camera Shots and Synthetic Images from Point Clouds

    Science.gov (United States)

    Boerner, R.; Kröhnert, M.

    2016-06-01

    3D point clouds, acquired by state-of-the-art terrestrial laser scanning techniques (TLS), provide spatial information about accuracies up to several millimetres. Unfortunately, common TLS data has no spectral information about the covered scene. However, the matching of TLS data with images is important for monoplotting purposes and point cloud colouration. Well-established methods solve this issue by matching of close range images and point cloud data by fitting optical camera systems on top of laser scanners or rather using ground control points. The approach addressed in this paper aims for the matching of 2D image and 3D point cloud data from a freely moving camera within an environment covered by a large 3D point cloud, e.g. a 3D city model. The key advantage of the free movement affects augmented reality applications or real time measurements. Therefore, a so-called real image, captured by a smartphone camera, has to be matched with a so-called synthetic image which consists of reverse projected 3D point cloud data to a synthetic projection centre whose exterior orientation parameters match the parameters of the image, assuming an ideal distortion free camera.

  19. Image registration of interferometric inverse synthetic aperture radar imaging system based on joint respective window sampling and modified motion compensation

    Science.gov (United States)

    Tian, Biao; Shi, Si; Liu, Yang; Xu, Shiyou; Chen, Zengping

    2015-01-01

    We propose a new image registration method based on joint respective window sampling (RWS) and modified motion compensation (MMC) in an interferometric inverse synthetic aperture radar (InISAR) imaging system using two antennas. The causation and quantitative analysis of the offset between two ISAR images of different antennas along the baseline are analyzed. In the proposed method, the RWS method, according to the measured distance between the target and different antennas, compensates the offset in the range direction. The MMC method is adopted to eliminate the offset in the Doppler direction. Simulation results demonstrate that the offset between the two ISAR images can be compensated effectively, consequently achieving a high-quality three-dimensional InISAR image.

  20. In vivo visualization of robotically implemented synthetic tracked aperture ultrasound (STRATUS) imaging system using curvilinear array

    Science.gov (United States)

    Zhang, Haichong K.; Aalamifar, Fereshteh; Boctor, Emad M.

    2016-04-01

    Synthetic aperture for ultrasound is a technique utilizing a wide aperture in both transmit and receive to enhance the ultrasound image quality. The limitation of synthetic aperture is the maximum available aperture size limit determined by the physical size of ultrasound probe. We propose Synthetic-Tracked Aperture Ultrasound (STRATUS) imaging system to overcome the limitation by extending the beamforming aperture size through ultrasound probe tracking. With a setup involving a robotic arm, the ultrasound probe is moved using the robotic arm, while the positions on a scanning trajectory are tracked in real-time. Data from each pose are synthesized to construct a high resolution image. In previous studies, we have demonstrated the feasibility through phantom experiments. However, various additional factors such as real-time data collection or motion artifacts should be taken into account when the in vivo target becomes the subject. In this work, we build a robot-based STRATUS imaging system with continuous data collection capability considering the practical implementation. A curvilinear array is used instead of a linear array to benefit from its wider capture angle. We scanned human forearms under two scenarios: one submerged the arm in the water tank under 10 cm depth, and the other directly scanned the arm from the surface. The image contrast improved 5.51 dB, and 9.96 dB for the underwater scan and the direct scan, respectively. The result indicates the practical feasibility of STRATUS imaging system, and the technique can be potentially applied to the wide range of human body.

  1. Synthetically Focused Imaging Techniques in Simulated Austenitic Steel Welds Using AN Ultrasonic Phased Array

    Science.gov (United States)

    Connolly, G. D.; Lowe, M. J. S.; Rokhlin, S. I.; Temple, J. A. G.

    2010-02-01

    In austenitic steel welds employed in safety-critical applications, detection of defects that may propagate during service or may have occurred during welding is particularly important. In this study, synthetically focused imaging techniques are applied to the echoes received by phased arrays in order to reconstruct images of the interior of a simulated austenitic steel weld, with application to sizing and location of simplified defects. Using a ray-tracing approach through a previously developed weld model, we briefly describe and then apply three focusing techniques. Results generated via both ray-tracing theory and finite element simulations will be shown.

  2. Synthetic aperture microwave imaging with active probing for fusion plasma diagnostics

    Energy Technology Data Exchange (ETDEWEB)

    Shevchenko, Vladimir F.; Freethy, Simon J.; Huang, Billy K. [EURATOM/CCFE Fusion Association, Culham, Abingdon, Oxon, 0X14 3DB (United Kingdom); Vann, Roddy G. L. [York Plasma Institute, Dept. of Physics, University of York, York YO10 5DD (United Kingdom)

    2014-08-21

    A Synthetic Aperture Microwave Imaging (SAMI) system has been designed and built to obtain 2-D images at several frequencies from fusion plasmas. SAMI uses a phased array of linearly polarised antennas. The array configuration has been optimised to achieve maximum synthetic aperture beam efficiency. The signals received by antennas are down-converted to the intermediate frequency range and then recorded in a full vector form. Full vector signals allow beam focusing and image reconstruction in both real time and a post-processing mode. SAMI can scan over 16 pre-programmed frequencies in the range of 10-35GHz with a switching time of 300ns. The system operates in 2 different modes simultaneously: both a 'passive' imaging of plasma emission and also an 'active' imaging of the back-scattered signal of the radiation launched by one of the antennas from the same array. This second mode is similar to so-called Doppler backscattering (DBS) reflectometry with 2-D resolution of the propagation velocity of turbulent structures. Both modes of operation show good performance in fusion plasma experiments on Mega Amp Spherical Tokamak (MAST). We have obtained the first ever 2-D images of BXO mode conversion windows. With active probing, first ever turbulence velocity maps have been obtained. We present an overview of the diagnostic and discuss recent results. In contrast to quasi-optical microwave imaging systems SAMI requires neither big aperture viewing ports nor large 2-D detector arrays to achieve the desired imaging resolution. The number of effective 'pixels' of the synthesized image is proportional to the number of receiving antennas squared. Thus only a small number of optimised antennas is sufficient for the majority of applications. Possible implementation of SAMI on ITERand DEMO is discussed.

  3. Synthetic aperture microwave imaging with active probing for fusion plasma diagnostics

    Science.gov (United States)

    Shevchenko, Vladimir F.; Freethy, Simon J.; Huang, Billy K.; Vann, Roddy G. L.

    2014-08-01

    A Synthetic Aperture Microwave Imaging (SAMI) system has been designed and built to obtain 2-D images at several frequencies from fusion plasmas. SAMI uses a phased array of linearly polarised antennas. The array configuration has been optimised to achieve maximum synthetic aperture beam efficiency. The signals received by antennas are down-converted to the intermediate frequency range and then recorded in a full vector form. Full vector signals allow beam focusing and image reconstruction in both real time and a post-processing mode. SAMI can scan over 16 pre-programmed frequencies in the range of 10-35GHz with a switching time of 300ns. The system operates in 2 different modes simultaneously: both a 'passive' imaging of plasma emission and also an 'active' imaging of the back-scattered signal of the radiation launched by one of the antennas from the same array. This second mode is similar to so-called Doppler backscattering (DBS) reflectometry with 2-D resolution of the propagation velocity of turbulent structures. Both modes of operation show good performance in fusion plasma experiments on Mega Amp Spherical Tokamak (MAST). We have obtained the first ever 2-D images of BXO mode conversion windows. With active probing, first ever turbulence velocity maps have been obtained. We present an overview of the diagnostic and discuss recent results. In contrast to quasi-optical microwave imaging systems SAMI requires neither big aperture viewing ports nor large 2-D detector arrays to achieve the desired imaging resolution. The number of effective 'pixels' of the synthesized image is proportional to the number of receiving antennas squared. Thus only a small number of optimised antennas is sufficient for the majority of applications. Possible implementation of SAMI on ITERand DEMO is discussed.

  4. Change Detection in Synthetic Aperture Radar Images Based on Deep Neural Networks.

    Science.gov (United States)

    Gong, Maoguo; Zhao, Jiaojiao; Liu, Jia; Miao, Qiguang; Jiao, Licheng

    2016-01-01

    This paper presents a novel change detection approach for synthetic aperture radar images based on deep learning. The approach accomplishes the detection of the changed and unchanged areas by designing a deep neural network. The main guideline is to produce a change detection map directly from two images with the trained deep neural network. The method can omit the process of generating a difference image (DI) that shows difference degrees between multitemporal synthetic aperture radar images. Thus, it can avoid the effect of the DI on the change detection results. The learning algorithm for deep architectures includes unsupervised feature learning and supervised fine-tuning to complete classification. The unsupervised feature learning aims at learning the representation of the relationships between the two images. In addition, the supervised fine-tuning aims at learning the concepts of the changed and unchanged pixels. Experiments on real data sets and theoretical analysis indicate the advantages, feasibility, and potential of the proposed method. Moreover, based on the results achieved by various traditional algorithms, respectively, deep learning can further improve the detection performance.

  5. Synthetic aperture microwave imaging with active probing for fusion plasma diagnostics

    CERN Document Server

    Shevchenko, Vladimir F; Freethy, Simon J; Huang, Billy K

    2012-01-01

    A Synthetic Aperture Microwave Imaging (SAMI) system has been designed and built to obtain 2-D images at several frequencies from fusion plasmas. SAMI uses a phased array of linearly polarised antennas. The array configuration has been optimised to achieve maximum synthetic aperture beam efficiency. The signals received by antennas are down-converted to the intermediate frequency range and then recorded in a full vector form. Full vector signals allow beam focusing and image reconstruction in both real time and a post processing mode. SAMI can scan over 16 preprogrammed frequencies in the range of 10-35GHz with a switching time of 300ns. The system operates in 2 different modes simultaneously: both a passive imaging of plasma emission and also an active imaging of the back-scattered signal of the radiation launched by one of the antennas from the same array. This second mode is similar to so-called Doppler backscattering (DBS) reflectometry with 2-D resolution of the propagation velocity of turbulent structur...

  6. Digital processing considerations for extraction of ocean wave image spectra from raw synthetic aperture radar data

    Science.gov (United States)

    Lahaie, I. J.; Dias, A. R.; Darling, G. D.

    1984-01-01

    The digital processing requirements of several algorithms for extracting the spectrum of a detected synthetic aperture radar (SAR) image from the raw SAR data are described and compared. The most efficient algorithms for image spectrum extraction from raw SAR data appear to be those containing an intermediate image formation step. It is shown that a recently developed compact formulation of the image spectrum in terms of the raw data is computationally inefficient when evaluated directly, in comparison with the classical method where matched-filter image formation is an intermediate result. It is also shown that a proposed indirect procedure for digitally implementing the same compact formulation is somewhat more efficient than the classical matched-filtering approach. However, this indirect procedure includes the image formation process as part of the total algorithm. Indeed, the computational savings afforded by the indirect implementation are identical to those obtained in SAR image formation processing when the matched-filtering algorithm is replaced by the well-known 'dechirp-Fourier transform' technique. Furthermore, corrections to account for slant-to-ground range conversion, spherical earth, etc., are often best implemented in the image domain, making intermediate image formation a valuable processing feature.

  7. Filtering and segmentation of the Cassini synthetic aperture radar images on Titan

    Science.gov (United States)

    Bratsolis, E.; Bampasidis, G.; Solomonidou, A.; Coustenis, A.; Hirtzig, M.

    2011-10-01

    A filtering technique is applied to obtain the restored synthetic aperture radar (SAR) images. One of the major problems hampering the derivation of meaningful texture information from SAR imagery is the speckle noise. It overlays "real" structures and causes gray value variations even in homogeneous parts of the image. Our method, the TSPR (total sum preserving regularization) filter, is based on probabilistic methods and regards an image as a random element drawn from a prespecified set of possible images optimized by a synchronous local iterative method. The despeckle filter can be used as intermediate stage for the extraction of meaningful regions that correspond to structural units in the scene or distinguish objects of interest like lakes, drainage networks, equatorial dunes or impact craters, where different textures appear.

  8. Feasibility study of synthetic aperture infrared laser radar techniques for imaging of static and moving objects.

    Science.gov (United States)

    Yoshikado, S; Aruga, T

    1998-08-20

    Techniques for two types of 10-mum band synthetic aperture infrared laser radar using a hypothetical reference point target (RPT) are presented. One is for imaging static objects with a single two-dimensional scanning aperture. Through the simple manipulation of a reference wave phase, a desired image can be obtained merely by the two-dimensional Fourier transformation of the correlator output between the intermediate frequency signals of the reference and object waves. The other, with a one-dimensional aperture array, is for moving objects that pass across the array direction without attitude change. We performed imaging by using a two-dimensional RPT correlation method. We demonstrate the capability of these methods for imaging and evaluate the necessary conditions for signal-to-noise ratio and random phase errors in signal reception through numerical simulations in terms of feasibility.

  9. A New Spaceborne Burst Synthetic Aperture Radar Imaging Mode for Wide Swath Coverage

    Directory of Open Access Journals (Sweden)

    Pingping Huang

    2014-01-01

    Full Text Available This paper presents a new spaceborne synthetic aperture radar (SAR burst mode named “Extended Terrain Observation by Progressive Scans (ETOPS” for wide swath imaged coverage. This scheme extends the imaging performance of the conventional Terrain Observation by Progressive Scans (TOPS mode with a very limited azimuth beam steering capability. Compared with the TOPS mode with the same azimuth beam steering range for the same swath width, a finer azimuth resolution could be obtained. With the same system parameters, examples of four burst SAR imaging modes named ScanSAR, TOPS, inverse TOPS (ITOPS and ETOPS are given, and their corresponding system performances are analyzed and compared. Simulation results show that the proposed ETOPS mode could obtain a better high-resolution wide-swath imaging performance under the same conditions.

  10. Acquiring multi-viewpoint image of 3D object for integral imaging using synthetic aperture phase-shifting digital holography

    Science.gov (United States)

    Jeong, Min-Ok; Kim, Nam; Park, Jae-Hyeung; Jeon, Seok-Hee; Gil, Sang-Keun

    2009-02-01

    We propose a method generating elemental images for the auto-stereoscopic three-dimensional display technique, integral imaging, using phase-shifting digital holography. Phase shifting digital holography is a way recording the digital hologram by changing phase of the reference beam and extracting the complex field of the object beam. Since all 3D information is captured by the phase-shifting digital holography, the elemental images for any specifications of the lens array can be generated from single phase-shifting digital holography. We expanded the viewing angle of the generated elemental image by using the synthetic aperture phase-shifting digital hologram. The principle of the proposed method is verified experimentally.

  11. Reverse Time Migration: A Seismic Imaging Technique Applied to Synthetic Ultrasonic Data

    Directory of Open Access Journals (Sweden)

    Sabine Müller

    2012-01-01

    Full Text Available Ultrasonic echo testing is a more and more frequently used technique in civil engineering to investigate concrete building elements, to measure thickness as well as to locate and characterise built-in components or inhomogeneities. Currently the Synthetic Aperture Focusing Technique (SAFT, which is closely related to Kirchhoff migration, is used in most cases for imaging. However, this method is known to have difficulties to image steeply dipping interfaces as well as lower boundaries of tubes, voids or similar objects. We have transferred a processing technique from geophysics, the Reverse Time Migration (RTM method, to improve the imaging of complicated geometries. By using the information from wide angle reflections as well as from multiple events there are fewer limitations compared to SAFT. As a drawback the required computing power is significantly higher compared to the techniques currently used. Synthetic experiments have been performed on polyamide and concrete specimens to show the improvements compared to SAFT. We have been able to image vertical interfaces of step-like structures as well as the lower boundaries of circular objects. It has been shown that RTM is a step forward for ultrasonic testing in civil engineering.

  12. Phase error suppression by low-pass filtering for synthetic aperture imaging ladar

    Science.gov (United States)

    Sun, Zhiwei; Hou, Peipei; Zhi, Ya'nan; Sun, Jianfeng; Zhou, Yu; Xu, Qian; Lu, Zhiyong; Liu, Liren

    2014-09-01

    Compared to synthetic aperture radar (SAR), synthetic aperture imaging ladar (SAIL) is more sensitive to the phase errors induced by atmospheric turbulence, undesirable line-of-sight translation-vibration and waveform phase error, because the light wavelength is about 3-6 orders of magnitude less than that of the radio frequency. This phase errors will deteriorate the imaging results. In this paper, an algorithm based on low-pass filtering to suppress the phase error is proposed. In this algorithm, the azimuth quadratic phase history with phase error is compensated, then the fast Fourier transform (FFT) is performed in azimuth direction, after the low-pass filtering, the inverse FFT is performed, then the image is reconstructed simultaneously in the range and azimuth direction by the two-dimensional (2D) FFT. The highfrequency phase error can be effectively eliminated hence the imaging results can be optimized by this algorithm. The mathematical analysis by virtue of data-collection equation of side-looking SAIL is presented. The theoretical modeling results are also given. In addition, based on this algorithm, a principle scheme of optical processor is proposed. The verified experiment is performed employing the data obtained from a SAIL demonstrator.

  13. Actinic imaging of native and programmed defects on a full-field mask

    Energy Technology Data Exchange (ETDEWEB)

    Mochi, I.; Goldberg, K. A.; Fontaine, B. La; Tchikoulaeva, A.; Holfeld, C.

    2010-03-12

    We describe the imaging and characterization of native defects on a full field extreme ultraviolet (EUV) mask, using several reticle and wafer inspection modes. Mask defect images recorded with the SEMA TECH Berkeley Actinic Inspection Tool (AIT), an EUV-wavelength (13.4 nm) actinic microscope, are compared with mask and printed-wafer images collected with scanning electron microscopy (SEM) and deep ultraviolet (DUV) inspection tools. We observed that defects that appear to be opaque in the SEM can be highly transparent to EUV light, and inversely, defects that are mostly transparent to the SEM can be highly opaque to EUV. The nature and composition of these defects, whether they appear on the top surface, within the multilayer coating, or on the substrate as buried bumps or pits, influences both their significance when printed, and their detectability with the available techniques. Actinic inspection quantitatively predicts the characteristics of printed defect images in ways that may not be possible with non-EUV techniques. As a quantitative example, we investigate the main structural characteristics of a buried pit defect based on EUV through-focus imaging.

  14. High frame rate synthetic aperture vector flow imaging for transthoracic echocardiography

    DEFF Research Database (Denmark)

    Villagómez Hoyos, Carlos Armando; Stuart, Matthias Bo; Bechsgaard, Thor

    2016-01-01

    This work presents the first in vivo results of 2-D high frame rate vector velocity imaging for transthoracic cardiac imaging. Measurements are made on a healthy volunteer using the SARUS experimental ultrasound scanner connected to an intercostal phased-array probe. Two parasternal long-axis view...... (PLAX) are obtained, one centred at the aortic valve and another centred at the left ventricle. The acquisition sequence was composed of 3 diverging waves for high frame rate synthetic aperture flow imaging. For verification a phantom measurement is performed on a transverse straight 5 mm diameter....... In-vivo acquisitions show complex flow patterns in the heart. In the aortic valve view, blood is seen exiting the left ventricle cavity through the aortic valve into the aorta during the systolic phase of the cardiac cycle. In the left ventricle view, blood flow is seen entering the left ventricle...

  15. Moving target detection in foliage using along track monopulse synthetic aperture radar imaging.

    Science.gov (United States)

    Soumekh, M

    1997-01-01

    This paper presents a method for detecting moving targets embedded in foliage from the monostatic and bistatic synthetic aperture radar (SAR) data obtained via two airborne radars. The two radars, which are mounted on the same aircraft, have different coordinates in the along track (cross-range) domain. However, unlike the interferometric SAR systems used for topographic mapping, the two radars possess a common range and altitude (i.e., slant range). The resultant monopulse SAR images are used to construct difference and interferometric images for moving target detection. It is shown that the signatures of the stationary targets are weakened in these images. Methods for estimating a moving target's motion parameters are discussed. Results for an ultrawideband UHF SAR system are presented.

  16. Synthetic phase holograms for auto-stereoscopic image displays using a modified IFTA

    Science.gov (United States)

    Choi, Kyongsik; Kim, Hwi; Lee, Byoungho

    2004-05-01

    A Fourier-transformed synthetic phase hologram for an auto-stereoscopic image display system is proposed and implemented. The system uses a phase-only spatial light modulator and a simple projection lens module. A modified iterative Fresnel transform algorithm method, for the reconstruction of gray-level quantized stereo images with fast convergence, high diffraction efficiency and large signal-to-noise ratio is also described. Using this method, it is possible to obtain a high diffraction efficiency(~90%), an excellent signal-to-noise ratio(> 9.6dB), and a short calculation time(~3min). Experimentally, the proposed auto-stereoscopic display system was able to generate stereoscopic 3D images very well.

  17. Efficient Terahertz Wide-Angle NUFFT-Based Inverse Synthetic Aperture Imaging Considering Spherical Wavefront.

    Science.gov (United States)

    Gao, Jingkun; Deng, Bin; Qin, Yuliang; Wang, Hongqiang; Li, Xiang

    2016-12-14

    An efficient wide-angle inverse synthetic aperture imaging method considering the spherical wavefront effects and suitable for the terahertz band is presented. Firstly, the echo signal model under spherical wave assumption is established, and the detailed wavefront curvature compensation method accelerated by 1D fast Fourier transform (FFT) is discussed. Then, to speed up the reconstruction procedure, the fast Gaussian gridding (FGG)-based nonuniform FFT (NUFFT) is employed to focus the image. Finally, proof-of-principle experiments are carried out and the results are compared with the ones obtained by the convolution back-projection (CBP) algorithm. The results demonstrate the effectiveness and the efficiency of the presented method. This imaging method can be directly used in the field of nondestructive detection and can also be used to provide a solution for the calculation of the far-field RCSs (Radar Cross Section) of targets in the terahertz regime.

  18. Synthetic aperture radar image correlation by use of preprocessing for enhancement of scattering centers.

    Science.gov (United States)

    Khoury, J; Gianino, P D; Woods, C L

    2000-10-15

    We demonstrate that a significant improvement can be obtained in the recognition of complicated synthetic aperture radar images taken from the Moving and Stationary Target Acquisitions and Recognition database. These images typically have a low number of scattering centers and high noise. We first preprocess the images and the templates formed from them so that their scattering centers are enhanced. Our technique can produce high-quality performance in several correlation criteria. For realistic automatic target recognition systems, our approach should make it easy to implement optical recognition systems with binarized data for many different types of correlation filter and should have a great effect on feeding data-compressed (binarized) information into either digital or optical processors.

  19. Speckle-reducing scale-invariant feature transform match for synthetic aperture radar image registration

    Science.gov (United States)

    Wang, Xianmin; Li, Bo; Xu, Qizhi

    2016-07-01

    The anisotropic scale space (ASS) is often used to enhance the performance of a scale-invariant feature transform (SIFT) algorithm in the registration of synthetic aperture radar (SAR) images. The existing ASS-based methods usually suffer from unstable keypoints and false matches, since the anisotropic diffusion filtering has limitations in reducing the speckle noise from SAR images while building the ASS image representation. We proposed a speckle reducing SIFT match method to obtain stable keypoints and acquire precise matches for the SAR image registration. First, the keypoints are detected in a speckle reducing anisotropic scale space constructed by the speckle reducing anisotropic diffusion, so that speckle noise is greatly reduced and prominent structures of the images are preserved, consequently the stable keypoints can be derived. Next, the probabilistic relaxation labeling approach is employed to establish the matches of the keypoints then the correct match rate of the keypoints is significantly increased. Experiments conducted on simulated speckled images and real SAR images demonstrate the effectiveness of the proposed method.

  20. Diagnostic value of the stand-alone synthetic image in digital breast tomosynthesis examinations.

    Science.gov (United States)

    Garayoa, Julia; Chevalier, Margarita; Castillo, Maria; Mahillo-Fernández, Ignacio; Amallal El Ouahabi, Najim; Estrada, Carmen; Tejerina, Alejandro; Benitez, Olivia; Valverde, Julio

    2017-08-15

    To demonstrate the non-inferiority of synthetic image (SI) mammography versus full-field digital mammography (FFDM) in breast tomosynthesis (DBT) examinations. An observational, retrospective, single-centre, multireader blinded study was performed, using 2384 images to directly compare SI and FFDM based on Breast Imaging Reporting and Data System (BIRADS) categorisation and visibility of radiological findings. Readers had no access to digital breast tomosynthesis slices. Multiple reader, multiple case (MRMC) receiver operating characteristic (ROC) methodology was used to compare the diagnostic performance of SI and FFDM images. The kappa statistic was used to estimate the inter-reader and intra-reader reliability. The area under the ROC curves (AUC) reveals the non-inferiority of SI versus FFDM based on BIRADS categorisation [difference between AUC (ΔAUC), -0.014] and lesion visibility (ΔAUC, -0.001) but the differences were not statistically significant (p=0.282 for BIRADS; p=0.961 for lesion visibility). On average, 77.4% of malignant lesions were detected with SI versus 76.5% with FFDM. Sensitivity and specificity of SI are superior to FFDM for malignant lesions scored as BIRADS 5 and breasts categorised as BIRADS 1. SI is not inferior to FFDM when DBT slices are not available during image reading. SI can replace FFDM, reducing the dose by 45%. • Stand-alone SI demonstrated performance not inferior for lesion visibility as compared to FFDM. • Stand-alone SI demonstrated performance not inferior for lesion BIRADS categorisation as compared to FFDM. • Synthetic images provide important dose savings in breast tomosynthesis examinations.

  1. Passive synthetic aperture hitchhiker imaging of ground moving targets--Part 1: image formation and velocity estimation.

    Science.gov (United States)

    Wacks, Steven; Yazici, Birsen

    2014-06-01

    In the Part 1 of this two-part study, we present a method of imaging and velocity estimation of ground moving targets using passive synthetic aperture radar. Such a system uses a network of small, mobile receivers that collect scattered waves due to transmitters of opportunity, such as commercial television, radio, and cell phone towers. Therefore, passive imaging systems have significant cost, manufacturing, and stealth advantages over active systems. We describe a novel generalized Radon transform-type forward model and a corresponding filtered-backprojection-type image formation and velocity estimation method. We form a stack of position images over a range of hypothesized velocities, and show that the targets can be reconstructed at the correct position whenever the hypothesized velocity is equal to the true velocity of targets. We then use entropy to determine the most accurate velocity and image pair for each moving target. We present extensive numerical simulations to verify the reconstruction method. Our method does not require a priori knowledge of transmitter locations and transmitted waveforms. It can determine the location and velocity of multiple targets moving at different velocities. Furthermore, it can accommodate arbitrary imaging geometries. In Part 2, we present the resolution analysis and analysis of positioning errors in passive SAR images due to erroneous velocity estimation.

  2. Change Detection in Synthetic Aperture Radar Images Using a Multiscale-Driven Approach

    Directory of Open Access Journals (Sweden)

    Olaniyi A. Ajadi

    2016-06-01

    Full Text Available Despite the significant progress that was achieved throughout the recent years, to this day, automatic change detection and classification from synthetic aperture radar (SAR images remains a difficult task. This is, in large part, due to (a the high level of speckle noise that is inherent to SAR data; (b the complex scattering response of SAR even for rather homogeneous targets; (c the low temporal sampling that is often achieved with SAR systems, since sequential images do not always have the same radar geometry (incident angle, orbit path, etc.; and (d the typically limited performance of SAR in delineating the exact boundary of changed regions. With this paper we present a promising change detection method that utilizes SAR images and provides solutions for these previously mentioned difficulties. We will show that the presented approach enables automatic and high-performance change detection across a wide range of spatial scales (resolution levels. The developed method follows a three-step approach of (i initial pre-processing; (ii data enhancement/filtering; and (iii wavelet-based, multi-scale change detection. The stand-alone property of our approach is the high flexibility in applying the change detection approach to a wide range of change detection problems. The performance of the developed approach is demonstrated using synthetic data as well as a real-data application to wildfire progression near Fairbanks, Alaska.

  3. Bistatic Synthetic Aperture Radar Imaging of Moving Targets using Ultra-Narrowband Continuous Waveforms

    CERN Document Server

    Wang, Ling

    2013-01-01

    We consider a synthetic aperture radar (SAR) system that uses ultra-narrowband continuous waveforms (CW) as an illumination source. Such a system has many practical advantages, such as the use of relatively simple, low-cost and low-power transmitters, and in some cases, using the transmitters of opportunity, such as TV, radio stations. Additionally, ultra-narrowband CW signals are suitable for motion estimation due to their ability to acquire high resolution Doppler information. In this paper, we present a novel synthetic aperture imaging method for moving targets using a bi-static SAR system transmitting ultra-narrowband continuous waveforms. Our method exploits the high Doppler resolution provided by ultra-narrowband CW signals to image both the scene reflectivity and to determine the velocity of multiple moving targets. Starting from the first principle, we develop a novel forward model based on the temporal Doppler induced by the movement of antennas and moving targets. We form the reflectivity image of t...

  4. Independent feature subspace iterative optimization based fuzzy clustering for synthetic aperture radar image segmentation

    Science.gov (United States)

    Yu, Hang; Xu, Luping; Feng, Dongzhu; He, Xiaochuan

    2015-01-01

    Synthetic aperture radar (SAR) image segmentation is investigated from feature extraction to algorithm design, which is characterized by two aspects: (1) multiple heterogeneous features are extracted to describe SAR images and the corresponding similarity measures are developed independently to avoid the mutual influences between different features in order to enhance the discriminability of the final similarity between objects. (2) A method called fuzzy clustering based on independent subspace iterative optimization (FCISIO) is proposed. FCISIO integrates multiple features into an objective function which is then iteratively optimized in each feature subspace to obtain final segmentation results. This strategy can protect the distribution structures of the data points in each feature subspace, which realizes an effective way to integrate multiple features of different properties. In order to improve the computation speed and the accuracy of feature description for FCISIO, we design a region merging algorithm before FCISIO which can use many kinds of information to quickly merge regions inside the true segments. Experiments on synthetic and real SAR images show that the proposed method is effective and robust and can obtain good segmentation results with a very short running time.

  5. Imaging approach for airborne stepped-frequency synthetic aperture radar in the squinted mode

    Science.gov (United States)

    Liu, Rengli; Wang, Yanfei

    2017-01-01

    For synthetic aperture radar (SAR) imaging, a stepped-frequency chirp signal is widely used to obtain ultrahigh range resolution. There are mainly two challenges in the stepped-frequency SAR imaging. One is the subbands synthesis, and the other is the estimation and compensation of amplitude and phase errors of the subbands caused by the radar system and the propagation. An imaging approach for the airborne squinted sliding-spotlight SAR with stepped-frequency chirps is proposed to achieve ultrahigh two-dimensional (2-D) resolution. Due to the squint angle, a Doppler centroid shift is introduced and then a modified space-variant compensation method for the range difference between the subbands is realized via multiplying a phase ramp in the 2-D frequency domain. Moreover, a range-dependent phase gradient autofocus algorithm based on raw data is proposed to estimate and compensate the residual phase error after the internal calibration. Afterward, the frequency-domain synthetic bandwidth method is used to complete the bandwidth synthesis. Finally, the extended Omega-K algorithm is applied to focus the synthesized data. The simulation results and the real data processing results prove the validity of the proposed approach.

  6. The optical synthetic aperture image restoration based on the improved maximum-likelihood algorithm

    Science.gov (United States)

    Geng, Zexun; Xu, Qing; Zhang, Baoming; Gong, Zhihui

    2012-09-01

    Optical synthetic aperture imaging (OSAI) can be envisaged in the future for improving the image resolution from high altitude orbits. Several future projects are based on optical synthetic aperture for science or earth observation. Comparing with equivalent monolithic telescopes, however, the partly filled aperture of OSAI induces the attenuation of the modulation transfer function of the system. Consequently, images acquired by OSAI instrument have to be post-processed to restore ones equivalent in resolution to that of a single filled aperture. The maximum-likelihood (ML) algorithm proposed by Benvenuto performed better than traditional Wiener filter did, but it didn't work stably and the point spread function (PSF), was assumed to be known and unchanged in iterative restoration. In fact, the PSF is unknown in most cases, and its estimation was expected to be updated alternatively in optimization. Facing these limitations of this method, an improved ML (IML) reconstruction algorithm was proposed in this paper, which incorporated PSF estimation by means of parameter identification into ML, and updated the PSF successively during iteration. Accordingly, the IML algorithm converged stably and reached better results. Experiment results showed that the proposed algorithm performed much better than ML did in peak signal to noise ratio, mean square error and the average contrast evaluation indexes.

  7. IFP V4.0:a polar-reformatting image formation processor for synthetic aperture radar.

    Energy Technology Data Exchange (ETDEWEB)

    Eichel, Paul H.

    2005-09-01

    IFP V4.0 is the fourth generation of an extraordinarily powerful and flexible image formation processor for spotlight mode synthetic aperture radar. It has been successfully utilized in processing phase histories from numerous radars and has been instrumental in the development of many new capabilities for spotlight mode SAR. This document provides a brief history of the development of IFP, a full exposition of the signal processing steps involved, and a short user's manual for the software implementing this latest iteration.

  8. A class of singular Fourier integral operators in synthetic aperture radar imaging

    CERN Document Server

    Ambartsoumian, G; Krishnan, V P; Nolan, C; Quinto, E T

    2011-01-01

    In this article, we analyze the microlocal properties of the linearized forward scattering operator $F$ and the normal operator $F^{*}F$ (where $F^{*}$ is the $L^{2}$ adjoint of $F$) which arises in Synthetic Aperture Radar imaging for the common midpoint acquisition geometry. When $F^{*}$ is applied to the scattered data, artifacts appear. We show that $F^{*}F$ can be decomposed as a sum of four operators, each belonging to a class of distributions associated to two cleanly intersecting Lagrangians, $I^{p,l} (\\Lambda_0, \\Lambda_1)$, thereby explaining the latter artifacts.

  9. Adaptive imaging cytometry to estimate parameters of gene networks models in systems and synthetic biology.

    Directory of Open Access Journals (Sweden)

    David A Ball

    Full Text Available The use of microfluidics in live cell imaging allows the acquisition of dense time-series from individual cells that can be perturbed through computer-controlled changes of growth medium. Systems and synthetic biologists frequently perform gene expression studies that require changes in growth conditions to characterize the stability of switches, the transfer function of a genetic device, or the oscillations of gene networks. It is rarely possible to know a priori at what times the various changes should be made, and the success of the experiment is unknown until all of the image processing is completed well after the completion of the experiment. This results in wasted time and resources, due to the need to repeat the experiment to fine-tune the imaging parameters. To overcome this limitation, we have developed an adaptive imaging platform called GenoSIGHT that processes images as they are recorded, and uses the resulting data to make real-time adjustments to experimental conditions. We have validated this closed-loop control of the experiment using galactose-inducible expression of the yellow fluorescent protein Venus in Saccharomyces cerevisiae. We show that adaptive imaging improves the reproducibility of gene expression data resulting in more accurate estimates of gene network parameters while increasing productivity ten-fold.

  10. Adaptive imaging cytometry to estimate parameters of gene networks models in systems and synthetic biology.

    Science.gov (United States)

    Ball, David A; Lux, Matthew W; Adames, Neil R; Peccoud, Jean

    2014-01-01

    The use of microfluidics in live cell imaging allows the acquisition of dense time-series from individual cells that can be perturbed through computer-controlled changes of growth medium. Systems and synthetic biologists frequently perform gene expression studies that require changes in growth conditions to characterize the stability of switches, the transfer function of a genetic device, or the oscillations of gene networks. It is rarely possible to know a priori at what times the various changes should be made, and the success of the experiment is unknown until all of the image processing is completed well after the completion of the experiment. This results in wasted time and resources, due to the need to repeat the experiment to fine-tune the imaging parameters. To overcome this limitation, we have developed an adaptive imaging platform called GenoSIGHT that processes images as they are recorded, and uses the resulting data to make real-time adjustments to experimental conditions. We have validated this closed-loop control of the experiment using galactose-inducible expression of the yellow fluorescent protein Venus in Saccharomyces cerevisiae. We show that adaptive imaging improves the reproducibility of gene expression data resulting in more accurate estimates of gene network parameters while increasing productivity ten-fold.

  11. Persistent scatterers detection on synthetic aperture radar images acquired by Sentinel-1 satellite

    Science.gov (United States)

    Dǎnişor, Cosmin; Popescu, Anca; Datcu, Mihai

    2016-12-01

    Persistent Scatterers Interferometry (PS-InSAR) has become a popular method in remote sensing because of its capability to measure terrain deformations with very high accuracy. It relies on multiple Synthetic Aperture Radar (SAR) acquisitions, to monitor points with stable proprieties over time, called Persistent Scatterers (PS)[1]. These points are unaffected by temporal decorrelation, therefore by analyzing their interferometric phase variation we can estimate the scene's deformation rates within a given time interval. In this work, we apply two incoherent detection algorithms to identify Persistent Scatterers candidates in the city of Focșani, Romania. The first method studies the variation of targets' intensities along the SAR acquisitions and the second method analyzes the spectral proprieties of the scatterers. The algorithms were implemented on a dataset containing 11 complex images of the region covering Buzău, Brăila and Focșani cities. Images were acquired by Sentinel-1 satellite in a time span of 5 months, from October 2014 to February 2015. The processing chain follows the requirements imposed by the new C-band SAR images delivered by the Sentinel-1 satellite (launched in April 2014) imaging in Interferometric Wide (IW) mode. Considering the particularities of the TOPS (Terrain Observation with Progressive Scans in Azimuth) imaging mode[2], special requirements had to be considered for pre-processing steps. The PS detection algorithms were implemented in Gamma RS program, a software which contains various function packages dedicated to SAR images focalization, analysis and processing.

  12. A fast level set method for synthetic aperture radar ocean image segmentation.

    Science.gov (United States)

    Huang, Xiaoxia; Huang, Bo; Li, Hongga

    2009-01-01

    Segmentation of high noise imagery like Synthetic Aperture Radar (SAR) images is still one of the most challenging tasks in image processing. While level set, a novel approach based on the analysis of the motion of an interface, can be used to address this challenge, the cell-based iterations may make the process of image segmentation remarkably slow, especially for large-size images. For this reason fast level set algorithms such as narrow band and fast marching have been attempted. Built upon these, this paper presents an improved fast level set method for SAR ocean image segmentation. This competent method is dependent on both the intensity driven speed and curvature flow that result in a stable and smooth boundary. Notably, it is optimized to track moving interfaces for keeping up with the point-wise boundary propagation using a single list and a method of fast up-wind scheme iteration. The list facilitates efficient insertion and deletion of pixels on the propagation front. Meanwhile, the local up-wind scheme is used to update the motion of the curvature front instead of solving partial differential equations. Experiments have been carried out on extraction of surface slick features from ERS-2 SAR images to substantiate the efficacy of the proposed fast level set method.

  13. Investigation on Beamspace Multiple-Input Multiple-Output Synthetic Aperture Radar Data Imaging

    Directory of Open Access Journals (Sweden)

    Hongbo Mo

    2016-01-01

    Full Text Available The multiple-input multiple-output (MIMO technique can improve the high-resolution wide-swath imaging capacity of synthetic aperture radar (SAR systems. Beamspace MIMO-SAR utilizes multiple subpulses transmitted with different time delays by different transmit beams to obtain more spatial diversities based on the relationship between the time delay and the elevation angle in the side-looking radar imaging geometry. This paper presents a beamspace MIMO-SAR imaging approach, which takes advantage of real time digital beamforming (DBF with null steering in elevation and azimuth multichannel raw data reconstruction. Echoes corresponding to different subpulses in the same subswath are separated by DBF with null steering onboard, while echoes received and stored by different azimuth channels are reconstructed by multiple Doppler reconstruction filters on the ground. Afterwards, the resulting MIMO-SAR raw data could be equivalent to the raw data of the single-channel burst mode, and classical burst mode imaging algorithms could be adopted to obtain final focused SAR images. Simulation results validate the proposed imaging approach.

  14. A synthetic luciferin improves in vivo bioluminescence imaging of gene expression in cardiovascular brain regions.

    Science.gov (United States)

    Simonyan, Hayk; Hurr, Chansol; Young, Colin N

    2016-10-01

    Bioluminescence imaging is an effective tool for in vivo investigation of molecular processes. We have demonstrated the applicability of bioluminescence imaging to spatiotemporally monitor gene expression in cardioregulatory brain nuclei during the development of cardiovascular disease, via incorporation of firefly luciferase into living animals, combined with exogenous d-luciferin substrate administration. Nevertheless, d-luciferin uptake into the brain tissue is low, which decreases the sensitivity of bioluminescence detection, particularly when considering small changes in gene expression in tiny central areas. Here, we tested the hypothesis that a synthetic luciferin, cyclic alkylaminoluciferin (CycLuc1), would be superior to d-luciferin for in vivo bioluminescence imaging in cardiovascular brain regions. Male C57B1/6 mice underwent targeted delivery of an adenovirus encoding the luciferase gene downstream of the CMV promoter to the subfornical organ (SFO) or paraventricular nucleus of hypothalamus (PVN), two crucial cardioregulatory neural regions. While bioluminescent signals could be obtained following d-luciferin injection (150 mg/kg), CycLuc1 administration resulted in a three- to fourfold greater bioluminescent emission from the SFO and PVN, at 10- to 20-fold lower substrate concentrations (7.5-15 mg/kg). This CycLuc1-mediated enhancement in bioluminescent emission was evident early following substrate administration (i.e., 6-10 min) and persisted for up to 1 h. When the exposure time was reduced from 60 s to 1,500 ms, minimal signal in the PVN was detectable with d-luciferin, whereas bioluminescent images could be reliably captured with CycLuc1. These findings demonstrate that bioluminescent imaging with the synthetic luciferin CycLuc1 provides an improved physiological genomics tool to investigate molecular events in discrete cardioregulatory brain nuclei.

  15. Anatomical standardization of small animal brain FDG-PET images using synthetic functional template: experimental comparison with anatomical template.

    Science.gov (United States)

    Coello, Christopher; Hjornevik, Trine; Courivaud, Frédéric; Willoch, Frode

    2011-07-15

    Anatomical standardization (also called spatial normalization) of positron emission tomography (PET) small animal brain images is required to make statistical comparisons across individuals. Frequently, PET images are co-registered to an individual MR or CT image of the same subject in order to transform the functional images to an anatomical space. In the present work, we evaluate the normalization of synthetic PET (synPET) images to a synthetic PET template. To provide absolute error in terms of pixel misregistration, we created a synthetic PET image from the individual MR image through segmentation of the brain into gray and white matter which produced functional and anatomical images in the same space. When comparing spatial normalization of synPET images to a synPET template with the gold standard (MR images to an MR template), a mean translation error of 0.24mm (±0.20) and a maximal mean rotational error of 0.85° (±0.91) were found. Significant decrease in misregistration error was measured when achieving spatial normalization of functional images to a functional template instead of an anatomical template. This accuracy strengthens the use of standardization methods where individual PET images are registered to a customized PET template in order to statistically assess physiological changes in rat brains.

  16. Adaptive grid-based confidence assessment for synthetic optoelectronic images by Physical Reasonable Infrared Scene Simulation Engine (PRISSE)

    Science.gov (United States)

    Wu, Xin; Sun, Hao; Ma, Xiangchao; Wang, Yucheng; Han, Yiping

    2017-09-01

    Like visible spectrum, synthetic infrared scenes reflect the invisible world of infrared features. Propagation of a typical infrared radiation involves a variety of sources of different sizes, shapes, intensities, roughness, temperature, etc., all of which would impose impacts on the fidelity of the synthetic images. Assessing the confidence of a synthetic infrared scene is therefore not so intuitive as evaluating the quality of a visible image. An adaptive grid-based method is proposed in this paper for similarity assessments between synthetic infrared images and the corresponding real infrared images, which is on a grid-by-grid basis. Different from many traditional methods, each grid in our work is weighted by a value that is simulated by a 2D Gamma distribution. Introducing adaptive grids and exerting a weighting value on each grid are the aspects of our method. To investigate the effectiveness of our method, an experiment was conducted for taking real mid-wavelength infrared (MWIR) images, and the corresponding synthetic MWIR images were simulated by Physical Reasonable Infrared Scene Simulation Engine (PRISSE). The confidence of similarity assessments evaluated by our method is then compared to some popularly-used traditional assessment methods.

  17. Graphene-based liquid-crystal microlens arrays for synthetic-aperture imaging

    Science.gov (United States)

    Wu, Yong; Hu, Wei; Tong, Qing; Lei, Yu; Xin, Zhaowei; Wei, Dong; Zhang, Xinyu; Liao, Jing; Wang, Haiwei; Xie, Changsheng

    2017-09-01

    In this paper, a new kind of liquid-crystal microlens array with graphene electrodes controlled electrically are designed and fabricated successfully. The graphene-based liquid-crystal microlens arrays (GLCMAs) exhibit excellent beam focusing performances in both the visible and near infrared (NIR) wavelength regions and also synthetic aperture imaging function. The graphene films used to fabricate the electrodes of the GLCMAs are grown by chemical vapor deposition over copper foils, demonstrating several characters of low sheet resistance and high transmittance in both wavelength ranges above. The key processes for shaping the GLCMAs include: transferring graphene films from copper foils to wafers selected, conventional UV-photolithography, ICP etching, and liquid-crystal encapsulation. Through performing common optical measurements, the point spread functions of incident lasers with different wavelength, such as red lasers of ∼600 nm, green lasers of ∼532 nm, and NIR lasers of ∼980 nm, have been obtained. Several key parameters including focal spots size, average normalized light intensity, focal length, average deviation rate and contrast ratio have been acquired and analyzed. A particular synthetic-aperture imaging based on the GLCMA is realized so as to certify a fact that a single target pattern can be constructed effectively based on some sub-aperture patterns with several tens or hundreds of micrometer scale, and thus highlight a way to fast process partial or small-zoned patterns for enhancing the detection efficiency of special targets.

  18. 3D terahertz synthetic aperture imaging of objects with arbitrary boundaries

    Science.gov (United States)

    Kniffin, G. P.; Zurk, L. M.; Schecklman, S.; Henry, S. C.

    2013-09-01

    Terahertz (THz) imaging has shown promise for nondestructive evaluation (NDE) of a wide variety of manufactured products including integrated circuits and pharmaceutical tablets. Its ability to penetrate many non-polar dielectrics allows tomographic imaging of an object's 3D structure. In NDE applications, the material properties of the target(s) and background media are often well-known a priori and the objective is to identify the presence and/or 3D location of structures or defects within. The authors' earlier work demonstrated the ability to produce accurate 3D images of conductive targets embedded within a high-density polyethylene (HDPE) background. That work assumed a priori knowledge of the refractive index of the HDPE as well as the physical location of the planar air-HDPE boundary. However, many objects of interest exhibit non-planar interfaces, such as varying degrees of curvature over the extent of the surface. Such irregular boundaries introduce refraction effects and other artifacts that distort 3D tomographic images. In this work, two reconstruction techniques are applied to THz synthetic aperture tomography; a holographic reconstruction method that accurately detects the 3D location of an object's irregular boundaries, and a split­-step Fourier algorithm that corrects the artifacts introduced by the surface irregularities. The methods are demonstrated with measurements from a THz time-domain imaging system.

  19. Passive Synthetic Aperture Hitchhiker Imaging of Ground Moving Targets - Part 2: Performance Analysis.

    Science.gov (United States)

    Wacks, Steven; Yazici, Birsen

    2014-07-08

    In Part 1 of this work, we present a passive synthetic aperture imaging and velocity estimation method for ground moving targets using a network of passive receivers. The method involves inversion of a Radon transform type forward model via a novel filtered backprojection approach combined with entropy optimization. The method is applicable to noncooperative transmitters of opportunity where the transmitter locations and transmitted waveforms are unknown. Furthermore, it can image multiple targets moving at different velocities in arbitrary imaging geometries. In this paper, we present a detailed analysis of the performance of our method. First the resolution analysis in position and velocity spaces is presented. The analysis identifies several factors that contribute positively or negativity towards position and velocity resolution. Next, we present a novel theory to analyze and predict smearing artifacts in position images due to error in velocity estimation of moving targets. Specifically, we show that small errors in the velocity estimation result in small positioning errors. We present extensive numerical simulations to demonstrate the theoretical results. While our primary interest lies in radar, the theory, methods and algorithms introduced in our work are also applicable to passive acoustic, seismic, and microwave imaging.

  20. Clinical evaluation of synthetic aperture harmonic imaging for scanning focal malignant liver lesions.

    Science.gov (United States)

    Brandt, Andreas Hjelm; Hemmsen, Martin Christian; Hansen, Peter Møller; Madsen, Signe Sloth; Krohn, Paul Suno; Lange, Theis; Hansen, Kristoffer Lindskov; Jensen, Jørgen Arendt; Nielsen, Michael Bachmann

    2015-09-01

    The purpose of the study was to perform a clinical comparison of synthetic aperture sequential beamforming tissue harmonic imaging (SASB-THI) sequences with a conventional imaging technique, dynamic receive focusing with THI (DRF-THI). Both techniques used pulse inversion and were recorded interleaved using a commercial ultrasound system (UltraView 800, BK Medical, Herlev, Denmark). Thirty-one patients with malignant focal liver lesions (confirmed by biopsy or computed tomography/magnetic resonance) were scanned. Detection of malignant focal liver lesions and preference of image quality were evaluated blinded off-line by eight radiologists. In total, 2,032 evaluations of 127 image sequences were completed. The sensitivity (77% SASB-THI, 76% DRF-THI, p = 0.54) and specificity (71% SASB-THI, 72% DRF-THI, p = 0.67) of detection of liver lesions and the evaluation of image quality (p = 0.63) did not differ between SASB-THI and DRF-THI. This study indicates the ability of SASB-THI in a true clinical setting. Copyright © 2015 World Federation for Ultrasound in Medicine & Biology. Published by Elsevier Inc. All rights reserved.

  1. A neural network for enhancing boundaries and surfaces in synthetic aperture radar images.

    Science.gov (United States)

    Mingolla, Ennio; Ross, William; Grossberg, Stephen

    1999-04-01

    A neural network system for boundary segmentation and surface representation, inspired by a new local-circuit model of visual processing in the cerebral cortex, is used to enhance images of range data gathered by a synthetic aperture radar (SAR) sensor. Boundary segmentation is accomplished by an improved Boundary Contour System (BCS) model which completes coherent boundaries that retain their sensitivity to image contrasts and locations. A Feature Contour System (FCS) model compensates for local contrast variations and uses the compensated signals to diffusively fill-in surface regions within the BCS boundaries. Image noise pixels that are not supported by BCS boundaries are hereby eliminated. More generally, BCS/FCS processing normalizes input dynamic range, reduces noise, and enhances contrasts between surface regions. BCS/FCS processing hereby makes structures such as motor vehicles, roads, and buildings more salient to human observers than in original imagery. The new BCS model improves image enhancement with significant reductions in processing time and complexity over previous BCS applications. The new system also outperforms several established techniques for image enhancement.

  2. A despeckle filter for the Cassini synthetic aperture radar images of Titan's surface

    Science.gov (United States)

    Bratsolis, Emmanuel; Bampasidis, Georgios; Solomonidou, Anezina; Coustenis, Athena

    2012-02-01

    Cassini synthetic aperture radar (SAR) images of Titan, the largest satellite of Saturn, reveal surface features with shapes ranging from quasi-circular to more complex ones, interpreted as liquid hydrocarbon deposits assembled in the form of lakes or seas. One of the major problems hampering the derivation of meaningful texture information from SAR imagery is the speckle noise. It overlays real structures and causes gray value variations even in homogeneous parts of the image. We propose a filtering technique which can be applied to obtain restored SAR images. Our technique is based on probabilistic methods and regards an image as a random element drawn from a prespecified set of possible images. The despeckle filter can be used as an intermediate step for the extraction of regions of interest, corresponding to structured units in a given area or distinct objects of interest, such as lake-like features on Titan. This tool can therefore be used, among other, to study seasonal surficial changes of Titan's polar regions. In this study we also present a segmentation technique that allows us to separate the lakes from the local background.

  3. Power versus performance tradeoffs of GPU-accelerated backprojection-based synthetic aperture radar image formation

    Science.gov (United States)

    Portillo, Ricardo; Arunagiri, Sarala; Teller, Patricia J.; Park, Song J.; Nguyen, Lam H.; Deroba, Joseph C.; Shires, Dale

    2011-06-01

    The continuing miniaturization and parallelization of computer hardware has facilitated the development of mobile and field-deployable systems that can accommodate terascale processing within once prohibitively small size and weight constraints. General-purpose Graphics Processing Units (GPUs) are prominent examples of such terascale devices. Unfortunately, the added computational capability of these devices often comes at the cost of larger demands on power, an already strained resource in these systems. This study explores power versus performance issues for a workload that can take advantage of GPU capability and is targeted to run in field-deployable environments, i.e., Synthetic Aperture Radar (SAR). Specifically, we focus on the Image Formation (IF) computational phase of SAR, often the most compute intensive, and evaluate two different state-of-the-art GPU implementations of this IF method. Using real and simulated data sets, we evaluate performance tradeoffs for single- and double-precision versions of these implementations in terms of time-to-solution, image output quality, and total energy consumption. We employ fine-grain direct-measurement techniques to capture isolated power utilization and energy consumption of the GPU device, and use general and radarspecific metrics to evaluate image output quality. We show that double-precision IF can provide slight image improvement to low-reflective areas of SAR images, but note that the added quality may not be worth the higher power and energy costs associated with higher precision operations.

  4. IMPROVED SYNTHETIC APERTURE SONAR MOTION COMPENSATION COMBINED DPCA WITH SUB-APERTURE IMAGE CORRELATION

    Institute of Scientific and Technical Information of China (English)

    Liu Wei; Zhang Chunhua; Liu Jiyuan

    2009-01-01

    Estimation precision of Displaced Phase Center Algorithm (DPCA) is affected by the number of displaced phase center pairs, the bandwidth of transmitting signal and many other factors. Detailed analysis is made on DPCA's estimation precision. Analysis results show that the directional vector estimation precision of DPCA is low, which will produce accumulating errors when phase centers' track is estimated. Because of this reason, DPCA suffers from accumulating errors seriously. To overcome this problem, a method combining DPCA with Sub Aperture Image Correlation (SAIC) is presented. Large synthetic aperture is divided into sub-apertures. Micro errors in sub-aperture are estimated by DPCA and compensated to raw echo data. Bulk errors between sub-apertures are estimated by SAIC and compensated directly to sub-aperture images. After that, sub-aperture images are directly used to generate ultimate SAS image. The method is applied to the lake-trial dataset of a 20 kHz SAS prototype system. Results show the method can successfully remove the accumulating error and produce a better SAS image.

  5. Exact spectrum of non-linear chirp scaling and its application in geosynchronous synthetic aperture radar imaging

    Directory of Open Access Journals (Sweden)

    Chen Qi

    2013-07-01

    Full Text Available Non-linear chirp scaling (NLCS is a feasible method to deal with time-variant frequency modulation (FM rate problem in synthetic aperture radar (SAR imaging. However, approximations in derivation of NLCS spectrum lead to performance decline in some cases. Presented is the exact spectrum of the NLCS function. Simulation with a geosynchronous synthetic aperture radar (GEO-SAR configuration is implemented. The results show that using the presented spectrum can significantly improve imaging performance, and the NLCS algorithm is suitable for GEO-SAR imaging after modification.

  6. Integration of speckle de-noising and image segmentation using Synthetic Aperture Radar image for flood extent extraction

    Indian Academy of Sciences (India)

    J Senthilnath; H Vikram Shenoy; Ritwik Rajendra; S N Omkar; V Mani; P G Diwakar

    2013-06-01

    Flood is one of the detrimental hydro-meteorological threats to mankind. This compels very efficient flood assessment models. In this paper, we propose remote sensing based flood assessment using Synthetic Aperture Radar (SAR) image because of its imperviousness to unfavourable weather conditions. However, they suffer from the speckle noise. Hence, the processing of SAR image is applied in two stages: speckle removal filters and image segmentation methods for flood mapping. The speckle noise has been reduced with the help of Lee, Frost and Gamma MAP filters. A performance comparison of these speckle removal filters is presented. From the results obtained, we deduce that the Gamma MAP is reliable. The selected Gamma MAP filtered image is segmented using Gray Level Co-occurrence Matrix (GLCM) and Mean Shift Segmentation (MSS). The GLCM is a texture analysis method that separates the image pixels into water and non-water groups based on their spectral feature whereas MSS is a gradient ascent method, here segmentation is carried out using spectral and spatial information. As test case, Kosi river flood is considered in our study. From the segmentation result of both these methods are comprehensively analysed and concluded that the MSS is efficient for flood mapping.

  7. Improving the Image Quality of Synthetic Transmit Aperture Ultrasound Images - Achieving Real-Time In-Vivo Imaging

    DEFF Research Database (Denmark)

    Gammelmark, Kim

    2004-01-01

    of convex array TMS imaging compared to conventional convex array imaging. Only minor motion artifacts causing subtle image brightness fluctuations were reported in TMS imaging, which did not depreciate the diagnostic value of the images. The influence of tissue motion and a method for two...

  8. Generation of synthetic CT data using patient specific daily MR image data and image registration

    Science.gov (United States)

    Melanie Kraus, Kim; Jäkel, Oliver; Niebuhr, Nina I.; Pfaffenberger, Asja

    2017-02-01

    To fully exploit the advantages of magnetic resonance imaging (MRI) for radiotherapy (RT) treatment planning, a method is required to overcome the problem of lacking electron density information. We aim to establish and evaluate a new method for computed tomography (CT) data generation based on MRI and image registration. The thereby generated CT data is used for dose accumulation. We developed a process flow based on an initial pair of rigidly co-registered CT and T2-weighted MR image representing the same anatomical situation. Deformable image registration using anatomical landmarks is performed between the initial MRI data and daily MR images. The resulting transformation is applied to the initial CT, thus fractional CT data is generated. Furthermore, the dose for a photon intensity modulated RT (IMRT) or intensity modulated proton therapy (IMPT) plan is calculated on the generated fractional CT and accumulated on the initial CT via inverse transformation. The method is evaluated by the use of phantom CT and MRI data. Quantitative validation is performed by evaluation of the mean absolute error (MAE) between the measured and the generated CT. The effect on dose accumulation is examined by means of dose-volume parameters. One patient case is presented to demonstrate the applicability of the method introduced here. Overall, CT data derivation lead to MAEs with a median of 37.0 HU ranging from 29.9 to 66.6 HU for all investigated tissues. The accuracy of image registration showed to be limited in the case of unexpected air cavities and at tissue boundaries. The comparisons of dose distributions based on measured and generated CT data agree well with the published literature. Differences in dose volume parameters kept within 1.6% and 3.2% for photon and proton RT, respectively. The method presented here is particularly suited for application in adaptive RT in current clinical routine, since only minor additional technical equipment is required.

  9. Volumetric synthetic aperture imaging with a piezoelectric 2D row-column probe

    Science.gov (United States)

    Bouzari, Hamed; Engholm, Mathias; Christiansen, Thomas Lehrmann; Beers, Christopher; Lei, Anders; Stuart, Matthias Bo; Nikolov, Svetoslav Ivanov; Thomsen, Erik Vilain; Jensen, Jørgen Arendt

    2016-04-01

    The synthetic aperture (SA) technique can be used for achieving real-time volumetric ultrasound imaging using 2-D row-column addressed transducers. This paper investigates SA volumetric imaging performance of an in-house prototyped 3 MHz λ/2-pitch 62+62 element piezoelectric 2-D row-column addressed transducer array. Utilizing single element transmit events, a volume rate of 90 Hz down to 14 cm deep is achieved. Data are obtained using the experimental ultrasound scanner SARUS with a 70 MHz sampling frequency and beamformed using a delay-and-sum (DAS) approach. A signal-to-noise ratio of up to 32 dB is measured on the beamformed images of a tissue mimicking phantom with attenuation of 0.5 dB cm-1 MHz-1, from the surface of the probe to the penetration depth of 300λ. Measured lateral resolution as Full-Width-at-Half-Maximum (FWHM) is between 4λ and 10λ for 18% to 65% of the penetration depth from the surface of the probe. The averaged contrast is 13 dB for the same range. The imaging performance assessment results may represent a reference guide for possible applications of such an array in different medical fields.

  10. Optimal waveform-based clutter suppression algorithm for recursive synthetic aperture radar imaging systems

    Science.gov (United States)

    Zhu, Binqi; Gao, Yesheng; Wang, Kaizhi; Liu, Xingzhao

    2016-04-01

    A computational method for suppressing clutter and generating clear microwave images of targets is proposed in this paper, which combines synthetic aperture radar (SAR) principles with recursive method and waveform design theory, and it is suitable for SAR for special applications. The nonlinear recursive model is introduced into the SAR operation principle, and the cubature Kalman filter algorithm is used to estimate target and clutter responses in each azimuth position based on their previous states, which are both assumed to be Gaussian distributions. NP criteria-based optimal waveforms are designed repeatedly as the sensor flies along its azimuth path and are used as the transmitting signals. A clutter suppression filter is then designed and added to suppress the clutter response while maintaining most of the target response. Thus, with fewer disturbances from the clutter response, we can generate the SAR image with traditional azimuth matched filters. Our simulations show that the clutter suppression filter significantly reduces the clutter response, and our algorithm greatly improves the SINR of the SAR image based on different clutter suppression filter parameters. As such, this algorithm may be preferable for special target imaging when prior information on the target is available.

  11. An extended chirp scaling algorithm for spaceborne sliding spotlight synthetic aperture radar imaging

    Directory of Open Access Journals (Sweden)

    Guo Jiao

    2014-08-01

    Full Text Available A system impulse response with low sidelobes is critical in synthetic aperture radar (SAR images because sidelobes contribute to noise and interfere with nearby scatterers. However, the conventional tricks of sidelobe suppression are unable to be exactly applied to the case of spaceborne sliding spotlight SAR due to great azimuth shifts in both time and frequency domains. In this paper, an extended chirp scaling algorithm is presented for spaceborne sliding spotlight SAR data imaging. The proposed algorithm firstly uses the spectral analysis (SPECAN technique to avoid the azimuth spectrum folding effect and then employs the chirp scaling (CS algorithm to achieve data focusing, i.e., the so-called two-step approach. To suppress the sidelobe level, an efficient strategy for the azimuth spectral weighting which only involves matrix multiplications and short fast Fourier transformations (FFTs is proposed, which is a post-process executed on the focused SAR image and particularly simple to be implemented. The SAR image processed by the proposed extended CS algorithm is very precise and perfectly phase-preserving. In the end, computer simulation results verify the analysis and confirm the validity of the proposed algorithm.

  12. An extended chirp scaling algorithm for spaceborne sliding spotlight synthetic aperture radar imaging

    Institute of Scientific and Technical Information of China (English)

    Guo Jiao; Xu Youshuan; Fu Longsheng

    2014-01-01

    A system impulse response with low sidelobes is critical in synthetic aperture radar (SAR) images because sidelobes contribute to noise and interfere with nearby scatterers. However, the conventional tricks of sidelobe suppression are unable to be exactly applied to the case of space-borne sliding spotlight SAR due to great azimuth shifts in both time and frequency domains. In this paper, an extended chirp scaling algorithm is presented for spaceborne sliding spotlight SAR data imaging. The proposed algorithm firstly uses the spectral analysis (SPECAN) technique to avoid the azimuth spectrum folding effect and then employs the chirp scaling (CS) algorithm to achieve data focusing, i.e., the so-called two-step approach. To suppress the sidelobe level, an efficient strategy for the azimuth spectral weighting which only involves matrix multiplications and short fast Fourier transformations (FFTs) is proposed, which is a post-process executed on the focused SAR image and particularly simple to be implemented. The SAR image processed by the proposed extended CS algorithm is very precise and perfectly phase-preserving. In the end, computer simulation results verify the analysis and confirm the validity of the proposed algorithm.

  13. Synthetic Aperture Microwave Imaging (SAMI) of the plasma edge on NSTX-U

    Science.gov (United States)

    Vann, Roddy; Taylor, Gary; Brunner, Jakob; Ellis, Bob; Thomas, David

    2016-10-01

    The Synthetic Aperture Microwave Imaging (SAMI) system is a unique phased-array microwave camera with a +/-40° field of view in both directions. It can image cut-off surfaces corresponding to frequencies in the range 10-34.5GHz; these surfaces are typically in the plasma edge. SAMI operates in two modes: either imaging thermal emission from the plasma (often modified by its interaction with the plasma edge e.g. via BXO mode conversion) or ``active probing'' i.e. injecting a broad beam at the plasma surface and imaging the reflected/back-scattered signal. SAMI was successfully pioneered on the Mega-Amp Spherical Tokamak (MAST) at Culham Centre for Fusion Energy. SAMI has now been installed and commissioned on the National Spherical Torus Experiment Upgrade (NSTX-U) at Princeton Plasma Physics Laboratory. The firmware has been upgraded to include real-time digital filtering, which enables continuous acquisition of the Doppler back-scattered active probing data. In this poster we shall present SAMI's analysis of the plasma edge on NSTX-U including measurements of the edge pitch angle on NSTX-U using SAMI's unique 2-D Doppler-backscattering capability.

  14. Precise reconstruction of fast moving cardiac valve in high frame rate synthetic transmit aperture ultrasound imaging

    Science.gov (United States)

    Suzuki, Mayumi; Ikeda, Teiichiro; Ishihara, Chizue; Takano, Shinta; Masuzawa, Hiroshi

    2016-04-01

    To diagnose heart valve incompetence, i.e., one of the most serious cardiac dysfunctions, it is essential to obtain images of fast-moving valves at high spatial and temporal resolution. Ultrasound synthetic transmit aperture (STA) imaging has the potential to achieve high spatial resolution by synthesizing multiple pre-beamformed images obtained with corresponding multiple transmissions. However, applying STA to fast-moving targets is difficult due to serious target deformation. We propose a high-frame-rate STA (fast STA) imaging method that uses a reduced number of transmission events needed for each image. Fast STA is expected to suppress deformation of moving targets; however, it may result in deteriorated spatial resolution. In this study, we conducted a simulation study to evaluate fast STA. We quantitatively evaluated the reduction in deformation and deterioration of spatial resolution with a model involving a radially moving valve at the maximum speed of 0.5 m/s. The simulated raw channel data of the valve phantom was processed with offline beamforming programs. We compared B-mode images obtained through single received-line in a transmission (SRT) method, STA, and fast STA. The results show that fast STA with four-times-reduced events is superior in reconstructing the original shape of the moving valve to other methods. The accuracy of valve location is 97 and 100% better than those with SRT and STA, respectively. The resolution deterioration was found to be below the annoyance threshold considering the improved performance of the shape reconstruction. The obtained results are promising for providing more precise diagnostic information on cardiovascular diseases.

  15. Renal water molecular diffusion characteristics in healthy native kidneys: assessment with diffusion tensor MR imaging.

    Directory of Open Access Journals (Sweden)

    Zhenfeng Zheng

    Full Text Available BACKGROUND: To explore the characteristics of diffusion tensor imaging (DTI and magnetic resonance (MR imaging in healthy native kidneys. METHODS: Seventy-three patients without chronic kidney disease underwent DTI-MRI with spin echo-echo planar (SE-EPI sequences accompanied by an array spatial sensitivity encoding technique (ASSET. Cortical and medullary mean, axial and radial diffusivity (MD, AD and RD, fractional anisotropy (FA and primary, secondary and tertiary eigenvalues (λ1, λ2, λ3 were analysed in both kidneys and in different genders. RESULTS: Cortical MD, λ2, λ3, and RD values were higher than corresponding medullary values. The cortical FA value was lower than the medullary FA value. Medullary λ1 and RD values in the left kidney were lower than in the right kidney. Medullary λ2, and λ3 values in women were higher than those in men. Medullary FA values in women were lower than those in men. Medullary FA (r = 0.351, P = 0.002 and λ1 (r = 0.277, P = 0.018 positively correlated with eGFR. Medullary FA (r = -0.25, P = 0.033 negatively correlated with age. CONCLUSIONS: Renal water molecular diffusion differences exist in human kidneys and genders. Age and eGFR correlate with medullary FA and primary eigenvalue.

  16. The migration of synthetic magnetic nanoparticle labeled dendritic cells into lymph nodes with optical imaging

    Directory of Open Access Journals (Sweden)

    Su H

    2013-10-01

    Full Text Available Hang Su,1,* Yongbin Mou,1,* Yanli An,2 Wei Han,1 Xiaofeng Huang,1 Guohua Xia,3 Yanhong Ni,1 Yu Zhang,4 Jianmin Ma,1 Qingang Hu1,5 1Center Laboratory of Stomatology, Stomatological Hospital Affiliated Medical School, Nanjing University, Nanjing, People's Republic of China; 2Jiangsu Key Lab of Molecular and Function Imaging, Department of Radiology; 3Department of Hematology, Zhongda Hospital, Medical School, 4State Key Laboratory of Molecule and Bimolecular Electronics, Jiangsu Provincial Laboratory for Biomaterials and Devices; Southeast University, Nanjing, People's Republic of China; 5Leeds Dental Institute, Faculty of Medicine and health, University of Leeds, Leeds, United Kingdom*These authors contributed equally to this workBackground: The successful biotherapy of carcinoma with dendritic cell (DC vaccines pivotally relies on DCs’ migratory capability into lymph tissues and activation of T cells. Accurate imaging and evaluation of DC migration in vivo have great significance during antitumor treatment with DC vaccine. We herein examined the behavior of DCs influenced by synthetic superparamagnetic iron oxide (SPIO nanoparticle labeling.Methods: γ-Fe2O3 nanoparticles were prepared and DCs, which were induced from bone marrow monocytes of enhanced green fluorescent protein (EGFP transgenic mice, were labeled. The endocytosis of the SPIO, surface molecules, cell apoptosis and fluorescence intensity of EGFP-DCs were displayed by Prussian blue staining and flow cytometry (FCM, respectively. After EGFP-DCs, labeled with SPIO, were injected into footpads (n = 5 for 24 hours, the mice were examined in vivo by optical imaging (OPI. Meanwhile, confocal imaging and FCM were applied, respectively, to detect the migration of labeled DCs into draining lymph nodes.Results: Nearly 100% of cells were labeled by the SPIO, in which the intracellular blue color gradually deepened and the iron contents rose with the increase of labeling iron concentrations

  17. Parameters estimation of sinusoidal frequency modulation signal with application in synthetic aperture radar imaging

    Science.gov (United States)

    Wang, Yong; Wang, Zhaofa; Zhao, Bin; Xu, Liang

    2016-04-01

    A method for estimating the parameters of the sinusoidal frequency modulation (SFM) signal is presented in this paper. Based on the modified discrete sinusoid frequency modulation transform (DSFMT), the SFM signal can be transformed into the DSFMT domain where it is energy-concentrated and then the parameters can be estimated by the global maximum. To search for the location of the global maximum with less computational load, particle swarm optimization is used in this paper. Then the algorithm is used in the synthetic aperture radar imaging with high frequency vibration of the platform, and the focus performance can be improved significantly. Simulation results demonstrate the effectiveness of the method proposed in this paper.

  18. Statistical-physical model for foliage clutter in ultra-wideband synthetic aperture radar images.

    Science.gov (United States)

    Banerjee, Amit; Chellappa, Rama

    2003-01-01

    Analyzing foliage-penetrating (FOPEN) ultra-wideband synthetic aperture radar (SAR) images is a challenging problem owing to the noisy and impulsive nature of foliage clutter. Indeed, many target-detection algorithms for FOPEN SAR data are characterized by high false-alarm rates. In this work, a statistical-physical model for foliage clutter is proposed that explains the presence of outliers in the data and suggests the use of symmetric alpha-stable (SalphaS) distributions for accurate clutter modeling. Furthermore, with the use of general assumptions of the noise sources and propagation conditions, the proposed model relates the parameters of the SalphaS model to physical parameters such as the attenuation coefficient and foliage density.

  19. Adaptive-neighborhood speckle removal in multitemporal synthetic aperture radar images.

    Science.gov (United States)

    Ciuc, M; Bolon, P; Trouve, E; Buzuloiu, V; Rudant, J P

    2001-11-10

    We present a new method for multitemporal synthetic aperture radar image filtering using three-dimensional (3D) adaptive neighborhoods. The method takes both spatial and temporal information into account to derive the speckle-free value of a pixel. For each pixel individually, a 3D adaptive neighborhood is determined that contains only pixels belonging to the same distribution as the current pixel. Then statistics computed inside the established neighborhood are used to derive the filter output. It is shown that the method provides good results by drastically reducing speckle over homogeneous areas while retaining edges and thin structures. The performances of the proposed method are compared in terms of subjective and objective measures with those given by several classical speckle-filtering methods.

  20. Synthetic aperture radar imaging based on attributed scatter model using sparse recovery techniques

    Institute of Scientific and Technical Information of China (English)

    苏伍各; 王宏强; 阳召成

    2014-01-01

    The sparse recovery algorithms formulate synthetic aperture radar (SAR) imaging problem in terms of sparse representation (SR) of a small number of strong scatters’ positions among a much large number of potential scatters’ positions, and provide an effective approach to improve the SAR image resolution. Based on the attributed scatter center model, several experiments were performed with different practical considerations to evaluate the performance of five representative SR techniques, namely, sparse Bayesian learning (SBL), fast Bayesian matching pursuit (FBMP), smoothed l0 norm method (SL0), sparse reconstruction by separable approximation (SpaRSA), fast iterative shrinkage-thresholding algorithm (FISTA), and the parameter settings in five SR algorithms were discussed. In different situations, the performances of these algorithms were also discussed. Through the comparison of MSE and failure rate in each algorithm simulation, FBMP and SpaRSA are found suitable for dealing with problems in the SAR imaging based on attributed scattering center model. Although the SBL is time-consuming, it always get better performance when related to failure rate and high SNR.

  1. On the convergence of the phase gradient autofocus algorithm for synthetic aperture radar imaging

    Energy Technology Data Exchange (ETDEWEB)

    Hicks, M.J.

    1996-01-01

    Synthetic Aperture Radar (SAR) imaging is a class of coherent range and Doppler signal processing techniques applied to remote sensing. The aperture is synthesized by recording and processing coherent signals at known positions along the flight path. Demands for greater image resolution put an extreme burden on requirements for inertial measurement units that are used to maintain accurate pulse-to-pulse position information. The recently developed Phase Gradient Autofocus algorithm relieves this burden by taking a data-driven digital signal processing approach to estimating the range-invariant phase aberrations due to either uncompensated motions of the SAR platform or to atmospheric turbulence. Although the performance of this four-step algorithm has been demonstrated, its convergence has not been modeled mathematically. A new sensitivity study of algorithm performance is a necessary step towards this model. Insights that are significant to the application of this algorithm to both SAR and to other coherent imaging applications are developed. New details on algorithm implementation identify an easily avoided biased phase estimate. A new algorithm for defining support of the point spread function is proposed, which promises to reduce the number of iterations required even for rural scenes with low signal-to-clutter ratios.

  2. Research on synthetic aperture radar imaging technology of one-dimensional layered rough surfaces

    Institute of Scientific and Technical Information of China (English)

    Ji Wei-Jie; Tong Chuang-Ming

    2013-01-01

    A quick and exact imaging method for one-dimensional layered rough surfaces is proposed in this paper to study the scattering characteristics of a layered medium that exists widely in nature.The boundary integral equations of layered rough surfaces are solved by using the propagation-inside-layer expansion combined with the forward and backward spectral acceleration method (PILE+FB-SA),and the back scattering data are obtained.Then,a conventional synthetic aperture radar (SAR) imaging procedure called back projection method is used to generate a two-dimensional (2D) image of the layered rough surfaces.Combined with the relative dielectric permittivity of realistic soil,the random rough surfaces with Gauss spectrum are used to simulate the layered medium with rough interfaces.Since the back scattering data are computed by using the fast numerical method,this method can be used to study layered rough surfaces with any parameter,which has a great application value in the detection and remote sensing areas.

  3. Parameter estimation and imaging of moving targets in bistatic synthetic aperture radar

    Science.gov (United States)

    Li, Yu; Huang, Puming; Yang, Zhimei; Lin, Chenchen

    2016-01-01

    In high-resolution bistatic synthetic aperture radar (SAR) systems, parameter estimation is essential to moving target imaging quality. However, precise parameters are difficult to obtain without priori information due to the relative along-track and across-track velocities between the moving target and platforms that change with time. A parameter estimation and imaging approach for moving targets is proposed. First, slant range and relative velocities expression are deduced based on the geometry of bistatic SAR model with one stationary configuration. Then, range curvature term are compensated skillfully by fitting the range-compressed curve in two-dimensional time domain, meanwhile, the initial estimated range walk slope can be achieved. Finally, precise Doppler centroid is estimated through searching for the maximum contrast with folding search algorithm, which is giving consideration to both searching precision and computational complexity. Thus, the proposed algorithm provides an effective way for parameter estimation and imaging of moving target without prior information and interpolation operation. Experimental results show the effectiveness of the proposed method.

  4. A method for automated snow avalanche debris detection through use of synthetic aperture radar (SAR) imaging

    Science.gov (United States)

    Vickers, H.; Eckerstorfer, M.; Malnes, E.; Larsen, Y.; Hindberg, H.

    2016-11-01

    Avalanches are a natural hazard that occur in mountainous regions of Troms County in northern Norway during winter and can cause loss of human life and damage to infrastructure. Knowledge of when and where they occur especially in remote, high mountain areas is often lacking due to difficult access. However, complete, spatiotemporal avalanche activity data sets are important for accurate avalanche forecasting, as well as for deeper understanding of the link between avalanche occurrences and the triggering snowpack and meteorological factors. It is therefore desirable to develop a technique that enables active mapping and monitoring of avalanches over an entire winter. Avalanche debris can be observed remotely over large spatial areas, under all weather and light conditions by synthetic aperture radar (SAR) satellites. The recently launched Sentinel-1A satellite acquires SAR images covering the entire Troms County with frequent updates. By focusing on a case study from New Year 2015 we use Sentinel-1A images to develop an automated avalanche debris detection algorithm that utilizes change detection and unsupervised object classification methods. We compare our results with manually identified avalanche debris and field-based images to quantify the algorithm accuracy. Our results indicate that a correct detection rate of over 60% can be achieved, which is sensitive to several algorithm parameters that may need revising. With further development and refinement of the algorithm, we believe that this method could play an effective role in future operational monitoring of avalanches within Troms and has potential application in avalanche forecasting areas worldwide.

  5. T2' imaging of native kidneys and renal allografts. A feasibility study

    Energy Technology Data Exchange (ETDEWEB)

    Mathys, C.; Blondin, D.; Wittsack, H.J.; Miese, F.R.; Rybacki, K.; Walther, C.; Holstein, A.; Lanzman, R.S. [Universitaetsklinikum Duesseldorf (Germany). Inst. fuer Radiologie

    2011-02-15

    Purpose: To evaluate the feasibility of T2' mapping in native kidneys and renal allografts. Materials and Methods: Following approval of the local ethics committee, 24 renal allograft recipients and 10 control subjects (healthy volunteers) were included in this study. Multi-echo T2 and T2{sup *} imaging was performed on a 1.5 Tesla scanner. Allograft recipients were assigned to two groups: group (a), 8 patients with good (glomerular filtration rate of more than 40 ml/min) allograft function and no evidence of transplant rejection, transplant renal artery stenosis or ureteral obstruction; group (b), 16 patients with deterioration of renal graft function (glomerular filtration rate (GFR) of 40 ml/min or less). Two different imaging protocols were tested. Results: The mean T2' relaxation parameters were 108.33 msec {+-} 13.34, 100.00 msec {+-} 18.89 and 124.57 msec {+-} 6.51 for groups (a), (b) and for control subjects, respectively. The reduction of T2' values in patient group (b) was not statistically significant. However, significant correlations could be demonstrated between T2' values and the glomerular filtration rate (GFR) of renal allograft function. The reproducibility was tested and the coefficients of variation of T2' values in the cortex of transplanted kidneys were 11.1 % within subjects and 11.3 % between subjects. Conclusion: Our results indicate that T2' imaging is a promising non-enhanced technique, which seems to reveal information on transplant function. Further studies are required to determine the clinical value of T2' mapping for monitoring renal allograft recipients. (orig.)

  6. Improving the Image Quality of Synthetic Transmit Aperture Ultrasound Images - Achieving Real-Time In-Vivo Imaging

    DEFF Research Database (Denmark)

    Gammelmark, Kim

    2004-01-01

    to increase the SNR, which employs multi-element subapertures and linearly frequency modulated (FM) signals at each emission. The subaperture is applied to emulate a high power spherical wave transmitted by a virtual point source positioned behind the subaperture, and the linear FM signal replaces...... in-vivo experiments, showed, that TMS imaging can increase the SNR by as much as 17 dB compared to the traditional imaging techniques, which improves the in-vivo image quality to a highly competitive level. An in-vivo evaluation of convex array TMS imaging for abdominal imaging applications...

  7. MR image-based synthetic CT for IMRT prostate treatment planning and CBCT image-guided localization.

    Science.gov (United States)

    Chen, Shupeng; Quan, Hong; Qin, An; Yee, Seonghwan; Yan, Di

    2016-05-08

    The purpose of this study was to propose and evaluate a method of creating a synthetic CT (S-CT) from MRI simulation for dose calculation and daily CBCT localization. A pair of MR and CT images was obtained in the same day from each of 10 prostate patients. The pair of MR and CT images was preregistered using the deformable image registration (DIR). Using the corresponding displacement vector field (atlas-DVF), the CT image was deformed to the MR image to create an atlas MR-CT pair. Regions of interest (ROI) on the atlas MR-CT pair were delineated and used to create atlas-ROI masks. 'Leave-one-out' test (one pair of MR and CT was used as subject-MR and subject-CT for evaluation, and the remaining 9 pairs were in the atlas library) was performed. For a subject-MR, autosegmentation and DVFs were generated using DIR between the subject-MR and the 9 atlas-MRs. An S-CT was then generated using the corresponding 9 paired atlas-CTs, the 9 atlas-DVFs and the corresponding atlas-ROI masks. The total 10 S-CTs were evaluated using the Hounsfield unit (HU), the calculated dose distribution, and the auto bony registration to daily CBCT images with respect to the 10 subject-CTs. HU differences (mean ± STD) were (2.4 ± 25.23), (1.18 ± 39.49), (32.46 ± 81.9), (0.23 ± 40.13), and (3.74 ± 144.76) for prostate, bladder, rectal wall, soft tissue outside all ROIs, and bone, respectively. The discrepancy of dose-volume param-eters calculated using the S-CT for treatment planning was small (≤ 0.22% with 95% confidence). Gamma pass rate (2% & 2 mm) was higher than 99.86% inside PTV and 98.45% inside normal structures. Using the 10 S-CTs as the reference CT for daily CBCT localization achieved the similar results compared to using the subject-CT. The translational vector differences were within 1.08 mm (0.37 ± 0.23 mm), and the rotational differences were within 1.1° in all three directions. S-CT created from a simulation MR image using the proposed approach with the

  8. Using hyperspectral imaging to determine germination of native Australian plant seeds.

    Science.gov (United States)

    Nansen, Christian; Zhao, Genpin; Dakin, Nicole; Zhao, Chunhui; Turner, Shane R

    2015-04-01

    We investigated the ability to accurately and non-destructively determine the germination of three native Australian tree species, Acacia cowleana Tate (Fabaceae), Banksia prionotes L.F. (Proteaceae), and Corymbia calophylla (Lindl.) K.D. Hill & L.A.S. Johnson (Myrtaceae) based on hyperspectral imaging data. While similar studies have been conducted on agricultural and horticultural seeds, we are unaware of any published studies involving reflectance-based assessments of the germination of tree seeds. Hyperspectral imaging data (110 narrow spectral bands from 423.6nm to 878.9nm) were acquired of individual seeds after 0, 1, 2, 5, 10, 20, 30, and 50days of standardized rapid ageing. At each time point, seeds were subjected to hyperspectral imaging to obtain reflectance profiles from individual seeds. A standard germination test was performed, and we predicted that loss of germination was associated with a significant change in seed coat reflectance profiles. Forward linear discriminant analysis (LDA) was used to select the 10 spectral bands with the highest contribution to classifications of the three species. In all species, germination decreased from over 90% to below 20% in about 10-30days of experimental ageing. P50 values (equal to 50% germination) for each species were 19.3 (A. cowleana), 7.0 (B. prionotes) and 22.9 (C. calophylla) days. Based on independent validation of classifications of hyperspectral imaging data, we found that germination of Acacia and Corymbia seeds could be classified with over 85% accuracy, while it was about 80% for Banksia seeds. The selected spectral bands in each LDA-based classification were located near known pigment peaks involved in photosynthesis and/or near spectral bands used in published indices to predict chlorophyll or nitrogen content in leaves. The results suggested that seed germination may be successfully classified (predicted) based on reflectance in narrow spectral bands associated with the primary metabolism

  9. Application of Multifractal Analysis to Segmentation of Water Bodies in Optical and Synthetic Aperture Radar Satellite Images

    CERN Document Server

    Martin, Victor Manuel San

    2016-01-01

    A method for segmenting water bodies in optical and synthetic aperture radar (SAR) satellite images is proposed. It makes use of the textural features of the different regions in the image for segmentation. The method consists in a multiscale analysis of the images, which allows us to study the images regularity both, locally and globally. As results of the analysis, coarse multifractal spectra of studied images and a group of images that associates each position (pixel) with its corresponding value of local regularity (or singularity) spectrum are obtained. Thresholds are then applied to the multifractal spectra of the images for the classification. These thresholds are selected after studying the characteristics of the spectra under the assumption that water bodies have larger local regularity than other soil types. Classifications obtained by the multifractal method are compared quantitatively with those obtained by neural networks trained to classify the pixels of the images in covered against uncovered b...

  10. Selective Synthetic Aperture Radar and Panchromatic Image Fusion by Using the à Trous Wavelet Decomposition

    Directory of Open Access Journals (Sweden)

    Youcef Chibani

    2005-08-01

    Full Text Available Synthetic aperture radar (SAR imaging sensor presents an important advantage for the earth change observation independently of weather conditions. However, the SAR image provides an incomplete information (as roads of the observed scene leading thus to an ambiguous interpretation. In order to compensate the lack of features, the high spatial resolution panchromatic (P image is often used as a complementary data for improving the quality of the SAR image. The concept is based on the extraction of features (details from the P image in order to incorporate into the SAR image. Therefore, we propose an approach based on the use of the à trous wavelet decomposition (ATWD for extracting features from the P image. Experimental results show that the SAR-P composite image allows a better detection of lines, edges, and field boundaries.

  11. Electromagnetic 3D subsurface imaging with source sparsity for a synthetic object

    CERN Document Server

    Pursiainen, Sampsa

    2016-01-01

    This paper concerns electromagnetic 3D subsurface imaging in connection with sparsity of signal sources. We explored an imaging approach that can be implemented in situations that allow obtaining a large amount of data over a surface or a set of orbits but at the same time require sparsity of the signal sources. Characteristic to such a tomography scenario is that it necessitates the inversion technique to be genuinely three-dimensional: For example, slicing is not possible due to the low number of sources. Here, we primarily focused on astrophysical subsurface exploration purposes. As an example target of our numerical experiments we used a synthetic small planetary object containing three inclusions, e.g. voids, of the size of the wavelength. A tetrahedral arrangement of source positions was used, it being the simplest symmetric point configuration in 3D. Our results suggest that somewhat reliable inversion results can be produced within the present a priori assumptions, if the data can be recorded at a spe...

  12. Detection and suppression of narrow band RFI for synthetic aperture radar imaging

    Directory of Open Access Journals (Sweden)

    Yang Lin

    2015-08-01

    Full Text Available Radio frequency interference (RFI is becoming more and more frequently, which makes it an important issue in SAR imaging. RFI presented in synthetic aperture radar either on purpose or inadvertent will distort the useful SAR echoes, thus degrade the SAR image quality. To resolve this issue, a long time study was carried out to study the characteristic of the RFI through the RFI-affected spaceborne and airborne SAR data. Based on the narrow band nature of RFI, this paper proposes a new process which contains both RFI detection and RFI suppression. A useful subband spectral kurtosis detector is first used to detect RFI, and then its results are used for RFI suppression. The proposed process has two advantages: one is the economization on the compute time for unnecessary interference suppression when no RFI existed; the other is improving the performance of the suppression method with knowing the exact position where RFI is. Moreover, the previous RFI suppression method—subband spectral cancelation (SSC is supplemented and perfected. The subband division step is also elaborated detail in this paper. The experiment results show that the subband spectral kurtosis detector exhibits good performance in recognizing both weak and narrow-band RFI. In addition, the validity of the SSC method with subband spectral kurtosis detector is also validated on the real SAR echoes.

  13. High-performance synthetic aperture radar image formation on commodity multicore architectures

    Science.gov (United States)

    McFarlin, Daniel S.; Franchetti, Franz; Püschel, Markus; Moura, José M. F.

    2009-05-01

    Synthetic Aperture Radar (SAR) image processing platforms have to process increasingly large datasets under and hard real-time deadlines. Upgrading these platforms is expensive. An attractive solution to this problem is to couple high performance, general-purpose Commercial-Off-The-Shelf (COTS) architectures such as IBM's Cell BE and Intel's Core with software implementations of SAR algorithms. While this approach provides great flexibility, achieving the requisite performance is difficult and time-consuming. The reason is the highly parallel nature and general complexity of modern COTS microarchitectures. To achieve the best performance, developers have to interweave of various complex optimizations including multithreading, the use of SIMD vector extensions, and careful tuning to the memory hierarchy. In this paper, we demonstrate the computer generation of high performance code for SAR implementations on Intel's multicore platforms based on the Spiral framework and system. The key is to express SAR and its building blocks in Spiral's formal domain-specific language to enable automatic vectorization, parallelization, and memory hierarchy tuning through rewriting at a high abstraction level and automatic exploration of choices. We show that Spiral produces code for the latest Intel quadcore platforms that surpasses competing hand-tuned implementations on the Cell Blade, an architecture with twice as many cores and three times the memory bandwidth. Specifically, we show an average performance of 39 Gigaflops/sec for 16-Megapixel and 100-Megapixel SAR images with runtimes of 0.56 and 3.76 seconds respectively.

  14. Monitoring water level using Sentinel-1 Interferometric Synthetic Aperture Radar (InSAR) images

    Science.gov (United States)

    Stavroulaki, Eleni; Alexakis, Dimitrios D.; Tsanis, Ioannis K.

    2017-04-01

    Interferometric Synthetic Aperture Radar (SAR) methodology can successfully detect phase variations related to water level changes and produce corresponding water level maps. Two lakes located in Western Crete, Greece, namely Lake Kournas and Lake Agia were used as case studies to study water level change with means of SAR interferometry. The change of the water surface in the lake is examined over a period of two years, 2015-2016 using Sentinel 1 IW mode images and in situ water level data. Initially, all the SAR images were preprocessed in terms of atmospheric and radiometric corrections. Various interferograms were developed to study the multi-temporal regime of water level in both lakes. Optical satellite sensor data (Landsat 8) were used to study the vegetation regime and how this affect the interferogram processing. The results denoted the fact that the combination of SAR backscattering intensity and unwrapped phase water level data can provide additional insight into hydrological state. It is also shown that integrated analysis of the backscattering mechanism and interferometric characteristics can considerably enhance the reliability of the water-level retrieval scheme and optimize the capture of hydrological patterns spatial distribution. Keywords: Sentinel-1, interferogram, water level, Backscattering

  15. Polarimetric synthetic aperture radar image unsupervised classification method based on artificial immune system

    Science.gov (United States)

    Jie, Yu; Gang, Wang; Teng, Zhu; Xiaojuan, Li; Qin, Yan

    2014-01-01

    An unsupervised classification method based on the H/α classifier and artificial immune system (AIS) is proposed to overcome the inefficiencies that arise when traditional classification methods deal with polarimetric synthetic aperture radar (PolSAR) data having large numbers of overlapping pixels and excess polarimetric information. The method is composed of two steps. First, Cloude-Pottier decomposition is used to obtain the entropy H and the scattering angle α. The classification result based on the H/α plane is used to initialize the AIS algorithm. Second, to obtain accurate results, the AIS clonal selection algorithm is used to perform an iterative calculation. As a self-organizing, self-recognizing, and self-optimizing algorithm, the AIS is able to obtain a global optimal solution and better classification results by making use of both the scattering mechanism of ground features and polarimetric scattering characteristics. The effectiveness and feasibility of this method are demonstrated by experiments using a NASA-JPL PolSAR image and a high-resolution PolSAR image of Lingshui autonomous county in Hainan Province.

  16. Signal processing techniques for forward imaging using ultrawideband synthetic aperture radar

    Science.gov (United States)

    Nguyen, Lam H.; Ton, Tuan T.; Wong, David C.; Ressler, Marc A.

    2003-09-01

    The U.S. Army Research Laboratory (ARL), as part of a customer and mission-funded exploratory development program, has been developing a prototype of low-frequency, ultra-wideband (UWB) forward-imaging synthetic aperture radar (SAR) to support the U.S. Army's vision for increased mobility and survivability of unmanned ground vehicle missions. The ability of the UWB radar technology to detect objects under foilage could provide an important obstacle-avoidance capability for robotic vehicles, which could improve the speed and maneuverability of these vehicles and consequently increase the survivability of the U.S. forces. In a recent experiment at Aberdeen Proving Ground (APG), we exercised the UWB SAR radar in forward-looking mode and collected data to support the investigation. This paper discusses the signal processing algorithms and techniques that we developed and applied to the recent UWB SAR forward-looking data. The algorithms include motion data processing, self-interference signal (SIR) removal, radio frequency interference (RFI) signal removal, forward-looking image formation, and visualization techniques. We present forward-loking SAR imagery and also volumetric imagery of some targets.

  17. Nonsearching Doppler parameter and velocity estimation method for synthetic aperture radar ground moving target imaging

    Science.gov (United States)

    Li, Zhongyu; Wu, Junjie; Huang, Yunlin; Yang, Haiguang; Yang, Jianyu

    2016-07-01

    For synthetic aperture radar (SAR), ground moving target (GMT) imaging necessitates the compensation of the additional azimuth modulation contributed by the unknown movement of the GMT. That is to say, it is necessary to estimate the Doppler parameters of the GMT without a priori knowledge of the GMT's motion parameters. This paper presents a Doppler parameter and velocity estimation method to refocus the GMT from its smeared response in SAR image. The main idea of this method is that an azimuth reference function is constructed to do the correlation integral with the azimuth signal of the GMT. And in general, the Doppler parameters of the presumed azimuth reference function are different from those of the GMT's azimuth signal since the velocity parameters of the GMT are unknown. Therefore, the correlation operation referred to here is actually mismatched, and the processing result of is shifted and defocused. The shifted and defocused result is utilized to get the real Doppler parameters and the velocity parameters of the GMT. One advantage of this method is that it is a nonsearching method. Another advantage is that both the Doppler centroid and the Doppler frequency rate of the GMT can be simultaneously estimated according to the relationships between the Doppler parameters and the smeared response of the GMT. In addition, the velocity of the GMT can also be obtained based on the estimated Doppler parameters. Numerical simulations and experimental data processing verify the validity of the method proposed.

  18. Synthetic aperture acoustic imaging of canonical targets with a 2-15 kHz linear FM chirp

    Science.gov (United States)

    Vignola, Joseph F.; Judge, John A.; Good, Chelsea E.; Bishop, Steven S.; Gugino, Peter M.; Soumekh, Mehrdad

    2011-06-01

    Synthetic aperture image reconstruction applied to outdoor acoustic recordings is presented. Acoustic imaging is an alternate method having several military relevant advantages such as being immune to RF jamming, superior spatial resolution, capable of standoff side and forward-looking scanning, and relatively low cost, weight and size when compared to 0.5 - 3 GHz ground penetrating radar technologies. Synthetic aperture acoustic imaging is similar to synthetic aperture radar, but more akin to synthetic aperture sonar technologies owing to the nature of longitudinal or compressive wave propagation in the surrounding acoustic medium. The system's transceiver is a quasi mono-static microphone and audio speaker pair mounted on a rail 5meters in length. Received data sampling rate is 80 kHz with a 2- 15 kHz Linear Frequency Modulated (LFM) chirp, with a pulse repetition frequency (PRF) of 10 Hz and an inter-pulse period (IPP) of 50 milliseconds. Targets are positioned within the acoustic scene at slant range of two to ten meters on grass, dirt or gravel surfaces, and with and without intervening metallic chain link fencing. Acoustic image reconstruction results in means for literal interpretation and quantifiable analyses. A rudimentary technique characterizes acoustic scatter at the ground surfaces. Targets within the acoustic scene are first digitally spotlighted and further processed, providing frequency and aspect angle dependent signature information.

  19. Real-time implementation of frequency-modulated continuous-wave synthetic aperture radar imaging using field programmable gate array.

    Science.gov (United States)

    Quan, Yinghui; Li, Yachao; Hu, Guibin; Xing, Mengdao

    2015-06-01

    A new miniature linear frequency-modulated continuous-wave radar which mounted on an unmanned aerial vehicle is presented. It allows the accomplishment of high resolution synthetic aperture radar imaging in real-time. Only a Kintex-7 field programmable gate array from Xilinx is utilized for whole signal processing of sophisticated radar imaging algorithms. The proposed hardware architecture achieves remarkable improvement in integration, power consumption, volume, and computing performance over its predecessor designs. The realized design is verified by flight campaigns.

  20. Software-based high-level synthesis design of FPGA beamformers for synthetic aperture imaging.

    Science.gov (United States)

    Amaro, Joao; Yiu, Billy Y S; Falcao, Gabriel; Gomes, Marco A C; Yu, Alfred C H

    2015-05-01

    Field-programmable gate arrays (FPGAs) can potentially be configured as beamforming platforms for ultrasound imaging, but a long design time and skilled expertise in hardware programming are typically required. In this article, we present a novel approach to the efficient design of FPGA beamformers for synthetic aperture (SA) imaging via the use of software-based high-level synthesis techniques. Software kernels (coded in OpenCL) were first developed to stage-wise handle SA beamforming operations, and their corresponding FPGA logic circuitry was emulated through a high-level synthesis framework. After design space analysis, the fine-tuned OpenCL kernels were compiled into register transfer level descriptions to configure an FPGA as a beamformer module. The processing performance of this beamformer was assessed through a series of offline emulation experiments that sought to derive beamformed images from SA channel-domain raw data (40-MHz sampling rate, 12 bit resolution). With 128 channels, our FPGA-based SA beamformer can achieve 41 frames per second (fps) processing throughput (3.44 × 10(8) pixels per second for frame size of 256 × 256 pixels) at 31.5 W power consumption (1.30 fps/W power efficiency). It utilized 86.9% of the FPGA fabric and operated at a 196.5 MHz clock frequency (after optimization). Based on these findings, we anticipate that FPGA and high-level synthesis can together foster rapid prototyping of real-time ultrasound processor modules at low power consumption budgets.

  1. High-resolution nondestructive testing of multilayer dielectric materials using wideband microwave synthetic aperture radar imaging

    Science.gov (United States)

    Kim, Tae Hee; James, Robin; Narayanan, Ram M.

    2017-04-01

    Fiber Reinforced Polymer or Plastic (FRP) composites have been rapidly increasing in the aerospace, automotive and marine industry, and civil engineering, because these composites show superior characteristics such as outstanding strength and stiffness, low weight, as well as anti-corrosion and easy production. Generally, the advancement of materials calls for correspondingly advanced methods and technologies for inspection and failure detection during production or maintenance, especially in the area of nondestructive testing (NDT). Among numerous inspection techniques, microwave sensing methods can be effectively used for NDT of FRP composites. FRP composite materials can be produced using various structures and materials, and various defects or flaws occur due to environmental conditions encountered during operation. However, reliable, low-cost, and easy-to-operate NDT methods have not been developed and tested. FRP composites are usually produced as multilayered structures consisting of fiber plate, matrix and core. Therefore, typical defects appearing in FRP composites are disbondings, delaminations, object inclusions, and certain kinds of barely visible impact damages. In this paper, we propose a microwave NDT method, based on synthetic aperture radar (SAR) imaging algorithms, for stand-off imaging of internal delaminations. When a microwave signal is incident on a multilayer dielectric material, the reflected signal provides a good response to interfaces and transverse cracks. An electromagnetic wave model is introduced to delineate interface widths or defect depths from the reflected waves. For the purpose of numerical analysis and simulation, multilayered composite samples with various artificial defects are assumed, and their SAR images are obtained and analyzed using a variety of high-resolution wideband waveforms.

  2. A Framework for the Generation of Realistic Synthetic Cardiac Ultrasound and Magnetic Resonance Imaging Sequences from the same Virtual Patients.

    Science.gov (United States)

    Zhou, Yitian; Giffard-Roisin, Sophie; De Craene, Mathieu; Camarasu-Pop, Sorina; D'hooge, Jan; Alessandrini, Martino; Friboulet, Denis; Sermesant, Maxime; Bernard, Olivier

    2017-05-25

    The use of synthetic sequences is one of the most promising tools for advanced in silico evaluation of the quantification of cardiac deformation and strain through 3D ultrasound (US) and magnetic resonance (MR) imaging. In this paper, we propose the first simulation framework which allows the generation of realistic 3D synthetic cardiac US and MR (both cine and tagging) image sequences from the same virtual patient. A state-of-the-art electromechanical (E/M) model was exploited for simulating groundtruth cardiac motion fields ranging from healthy to various pathological cases including both ventricular dyssynchrony and myocardial ischemia. The E/M groundtruth along with template MR/US images and physical simulators were combined in a unified framework for generating synthetic data. We efficiently merged several warping strategies to keep full control of myocardial deformations while preserving realistic image texture. In total, we generated 18 virtual patients, each with synthetic 3D US, cine MR and tagged MR sequences. The simulated images were evaluated both qualitatively by showing realistic textures and quantitatively by observing myocardial intensity distributions similar to real data. In particular, the US simulation showed a smoother myocardium/background interface than the state-of-the-art. We also assessed the mechanical properties. The pathological subjects were discriminated from the healthy ones by both global indexes (ejection fraction and the global circumferential strain) and regional strain curves. The synthetic database is comprehensive in terms of both pathology and modality, and has a level of realism sufficient for validation purposes. All the 90 sequences are made publicly available to the research community via an open-access database.

  3. Direct visualization of secretion from single bovine adrenal chromaffin cells by laser-induced native fluorescence imaging microscopy

    Energy Technology Data Exchange (ETDEWEB)

    Tong, W.; Yeung, E.S. [Ames Laboratory---USDOE and Department of Chemistry, Iowa State University, Ames, Iowa 50011 (United States)

    1998-03-01

    Direct visualization of the secretion process of individual bovine adrenal chromaffin cells was achieved with laser-induced native fluorescence imaging microscopy. By monitoring the native fluorescence of catecholamines excited by the 275 nm laser line with an intensified charge-coupled-device (CCD) camera, we obtained good temporal and spatial resolution simultaneously without using additional fluorescent probes. Large variations were found among individual cells in terms of the amounts of catecholamines secreted and the rates of secretion. Different regions of a cell also behave differently during the secretion process. However, the degree of this local heterogeneity is smaller than in neurons and neuralgia. The influence of deep-ultraviolet (UV) laser excitation on cells is also discussed. This quantitative imaging technique provides a useful noninvasive approach for the study of dynamic cellular changes and the understanding of the molecular mechanisms of secretory processes. {copyright} {ital 1998} {ital Society for Applied Spectroscopy}

  4. Synthetic Receive Beamforming and Image Acquisition Capabilities Using an 8 x 128 1.75D Array

    DEFF Research Database (Denmark)

    Fernandez, Anna T.; Gammelmark, Kim; Dahl, Jeremy J.;

    2003-01-01

    , several rows in elevation) through the use of synthetic elevation imaging. We describe synthetic elevation beamforming methods and its implementation with our 8 x 128, 1.75D array (Tetrad Co., Englewood, CO). This array has been successfully interfaced with a Siemens Elegra scanner for summed RF...... and single channel RIP data acquisition. Individual rows of the 8 x 128 array can be controlled, allowing for different aperture configurations on transmit and receive beamforming. Advantages of using this array include finer elevation sampling, a larger array footprint for aberration measurements...

  5. Application of Deep Networks to Oil Spill Detection Using Polarimetric Synthetic Aperture Radar Images

    Directory of Open Access Journals (Sweden)

    Guandong Chen

    2017-09-01

    Full Text Available Polarimetric synthetic aperture radar (SAR remote sensing provides an outstanding tool in oil spill detection and classification, for its advantages in distinguishing mineral oil and biogenic lookalikes. Various features can be extracted from polarimetric SAR data. The large number and correlated nature of polarimetric SAR features make the selection and optimization of these features impact on the performance of oil spill classification algorithms. In this paper, deep learning algorithms such as the stacked autoencoder (SAE and deep belief network (DBN are applied to optimize the polarimetric feature sets and reduce the feature dimension through layer-wise unsupervised pre-training. An experiment was conducted on RADARSAT-2 quad-polarimetric SAR image acquired during the Norwegian oil-on-water exercise of 2011, in which verified mineral, emulsions, and biogenic slicks were analyzed. The results show that oil spill classification achieved by deep networks outperformed both support vector machine (SVM and traditional artificial neural networks (ANN with similar parameter settings, especially when the number of training data samples is limited.

  6. Kernel linear representation: application to target recognition in synthetic aperture radar images

    Science.gov (United States)

    Dong, Ganggang; Wang, Na; Kuang, Gangyao; Zhang, Yinfa

    2014-01-01

    A method for target classification in synthetic aperture radar (SAR) images is proposed. The samples are first mapped into a high-dimensional feature space in which samples from the same class are assumed to span a linear subspace. Then, any new sample can be uniquely represented by the training samples within given constraint. The conventional methods suggest searching the sparest representations with ℓ1-norm (or ℓ) minimization constraint. However, these methods are computationally expensive due to optimizing nondifferential objective function. To improve the performance while reducing the computational consumption, a simple yet effective classification scheme called kernel linear representation (KLR) is presented. Different from the previous works, KLR limits the feasible set of representations with a much weaker constraint, ℓ-norm minimization. Since, KLR can be solved in closed form there is no need to perform the ℓ-minimization, and hence the calculation burden has been lessened. Meanwhile, the classification accuracy has been improved due to the relaxation of the constraint. Extensive experiments on a real SAR dataset demonstrate that the proposed method outperforms the kernel sparse models as well as the previous works performed on SAR target recognition.

  7. Hybrid Synthetic/Real Aperture Antenna for High Resolution Microwave Imaging

    Science.gov (United States)

    Doiron, Terence A.; Piepmeier, Jeffrey R.

    2003-01-01

    Observations of key hydrological parameters at the spatial and temporal scales required in the post-2002 era face significant technological challenges. These measurements are based on relatively low frequency thermal microwave emission (at 1.4 GHz for soil moisture and salinity, 10 GHz and up for precipitation, and 19 and 37 GHz for snow). The long wavelengths at these frequencies coupled with the high spatial and radiometric resolutions required by the various global hydrology missions necessitate the use of very large apertures. Two-dimensional Synthetic Thinned Array Radiometry (2-D STAR), though promising in the long term, has many technical challenges in the areas of power, and sensitivity for very large apertures (i.e. greater than 300 wavelengths). This paper will discuss an alternative approach to the pure 2-D STAR, which uses an offset parabolic cylinder reflector fed by multiple elements to form a 1-D STAR. In essence a single STAR element is composed of a feedhorn and parabolic cylinder reflector. The elements are sparsely arrayed and thus can share a single reflector. This antenna would have no moving parts once deployed, have much higher sensitivity than a Y-shaped 2-D STAR of equivalent size, many fewer receivers than that 2-D STAR, and the reflector could be made of a thin film and lightweight deployment system for high packing density. The instrument using this approach would be a cross track push broom imager. An overview of the design parameters, potential deployment mechanisms and applications will be presented.

  8. Hybrid Synthetic/Real Aperture Antenna for High Resolution Microwave Imaging

    Science.gov (United States)

    Doiron, Terence A.; Piepmeier, Jeffrey R.

    2003-01-01

    Observations of key hydrological parameters at the spatial and temporal scales required in the post-2002 era face significant technological challenges. These measurements are based on relatively low frequency thermal microwave emission (at 1.4 GHz for soil moisture and salinity, 10 GHz and up for precipitation, and 19 and 37 GHz for snow). The long wavelengths at these frequencies coupled with the high spatial and radiometric resolutions required by the various global hydrology missions necessitate the use of very large apertures. Two-dimensional Synthetic Thinned Array Radiometry (2-D STAR), though promising in the long term, has many technical challenges in the areas of power, and sensitivity for very large apertures (i.e. greater than 300 wavelengths). This paper will discuss an alternative approach to the pure 2-D STAR, which uses an offset parabolic cylinder reflector fed by multiple elements to form a 1-D STAR. In essence a single STAR element is composed of a feedhorn and parabolic cylinder reflector. The elements are sparsely arrayed and thus can share a single reflector. This antenna would have no moving parts once deployed, have much higher sensitivity than a Y-shaped 2-D STAR of equivalent size, many fewer receivers than that 2-D STAR, and the reflector could be made of a thin film and lightweight deployment system for high packing density. The instrument using this approach would be a cross track push broom imager. An overview of the design parameters, potential deployment mechanisms and applications will be presented.

  9. Advanced Interferometric Synthetic Aperture Imaging Radar (InSAR) for Dune Mapping

    Science.gov (United States)

    Havivi, Shiran; Amir, Doron; Schvartzman, Ilan; August, Yitzhak; Mamman, Shimrit; Rotman, Stanely R.; Blumberg, Dan G.

    2016-04-01

    Aeolian morphologies are formed in the presence of sufficient wind energy and available lose particles. These processes occur naturally or are further enhanced or reduced by human intervention. The dimensions of change are dependent primarily on the wind energy and surface properties. Since the 1970s, remote sensing imagery, both optical and radar, have been used for documentation and interpretation of the geomorphologic changes of sand dunes. Remote sensing studies of aeolian morphologies is mostly useful to document major changes, yet, subtle changes, occurring in a period of days or months in scales of centimeters, are very difficult to detect in imagery. Interferometric Synthetic Aperture Radar (InSAR) is an imaging technique for measuring Earth's surface topography and deformation. InSAR images are produced by measuring the radar phase difference between two separated antennas that view the same surface area. Classical InSAR is based on high coherence between two or more images. The output (interferogram) can show subtle changes with an accuracy of several millimeters to centimeters. Very little work has been done on measuring or identifying the changes in dunes using InSAR methods. The reason is that dunes tend to be less coherent than firm, stable, surfaces. This work aims to demonstrate how interferometric decorrelation can be used for identifying dune instability. We hypothesize and demonstrate that the loss of radar coherence over time on dunes can be used as an indication of the dune's instability. When SAR images are acquired at sufficiently close intervals one can measure the time it takes to lose coherence and associate this time with geomorphic stability. To achieve our goals, the coherence change detection method was used, in order to identify dune stability or instability and the dune activity level. The Nitzanim-Ashdod coastal dunes along the Mediterranean, 40 km south of Tel-Aviv, Israel, were chosen as a case study. The dunes in this area are of

  10. Two-beam-coupling correlator for synthetic aperture radar image recognition with power-law scattering centers preenhancement.

    Science.gov (United States)

    Haji-Saeed, Bahareh; Woods, Charles L; Kierstead, John; Khoury, Jed

    2008-06-01

    Synthetic radar image recognition is an area of interest for military applications including automatic target recognition, air traffic control, and remote sensing. Here a dynamic range compression two-beam-coupling joint transform correlator for detecting synthetic aperture radar targets is utilized. The joint input image consists of a prepower-law, enhanced scattering center of the input image and a linearly synthesized power-law-enhanced scattering center template. Enhancing the scattering center of both the synthetic template and the input image furnishes the conditions for achieving dynamic range compression correlation in two-beam coupling. Dynamic range compression (a) enhances the signal-to-noise ratio, (b) enhances the high frequencies relative to low frequencies, and (c) converts the noise to high frequency components. This improves the correlation-peak intensity to the mean of the surrounding noise significantly. Dynamic range compression correlation has already been demonstrated to outperform many optimal correlation filters in detecting signals in severe noise environments. The performance is evaluated via established metrics such as peak-to-correlation energy, Horner efficiency, and correlation-peak intensity. The results showed significant improvement as the power increased.

  11. USPIO-enhanced MR imaging of macrophage infiltration in native and transplanted kidneys: initial results in humans.

    Science.gov (United States)

    Hauger, Olivier; Grenier, Nicolas; Deminère, Colette; Lasseur, Catherine; Delmas, Yahsou; Merville, Pierre; Combe, Christian

    2007-11-01

    The purpose of this study was to evaluate the detection and characterization of macrophage infiltration in native and transplanted kidneys using ultrasmall superparamagnetic iron oxide particles (USPIO). Among 21 patients initially enrolled, 12 scheduled for renal biopsy for acute or rapidly progressive renal failure (n = 7) or renal graft rejection (n = 5) completed the study. Three magnetic resonance (MR) sessions were performed with a 1.5-T system, before, immediately after and 72 h after i.v. injection of USPIO at doses of 1.7-2.6 mg of iron/kg. Signal intensity change was evaluated visually and calculated based on a region of interest (ROI) positioned on the kidney compartments. Histological examination showed cortical macrophage infiltration in four patients (>5 macrophages/mm(2)), two in native kidneys (proliferative extracapillary glomerulonephritis) and two in transplants (acute rejection). These patients showed a 33 +/- 18% mean cortical signal loss on T2*-weighted images. In the remaining eight patients, with <5 macrophages/mm(2), there was no cortical signal loss. However, in three of these, presenting with ischemic acute tubular necrosis, a strong (42 +/- 18%) signal drop was found in the medulla exclusively. USPIO-enhanced MR imaging can demonstrate infiltration of the kidneys by macrophages both in native and transplanted kidneys and may help to differentiate between kidney diseases.

  12. USPIO-enhanced MR imaging of macrophage infiltration in native and transplanted kidneys: initial results in humans

    Energy Technology Data Exchange (ETDEWEB)

    Hauger, Olivier; Grenier, Nicolas [Service d' Imagerie Diagnostique et Therapeutique de l' Adulte, Groupe Hospitalier Pellegrin, Bordeaux Cedex (France); Laboratoire d' Imagerie Moleculaire et Fonctionnelle, ERT CNRS/Universite Victor Segalen Bordeaux 2, Bordeaux (France); Deminere, Colette [Service d' Anatomo-pathologie, Groupe Hospitalier Pellegrin, Bordeaux (France); Lasseur, Catherine; Delmas, Yahsou; Merville, Pierre; Combe, Christian [Departement de Nephrologie, Groupe Hospitalier Pellegrin, Bordeaux (France)

    2007-11-15

    The purpose of this study was to evaluate the detection and characterization of macrophage infiltration in native and transplanted kidneys using ultrasmall superparamagnetic iron oxide particles (USPIO). Among 21 patients initially enrolled, 12 scheduled for renal biopsy for acute or rapidly progressive renal failure (n = 7) or renal graft rejection (n = 5) completed the study. Three magnetic resonance (MR) sessions were performed with a 1.5-T system, before, immediately after and 72 h after i.v. injection of USPIO at doses of 1.7-2.6 mg of iron/kg. Signal intensity change was evaluated visually and calculated based on a region of interest (ROI) positioned on the kidney compartments. Histological examination showed cortical macrophage infiltration in four patients (>5 macrophages/mm{sup 2}), two in native kidneys (proliferative extracapillary glomerulonephritis) and two in transplants (acute rejection). These patients showed a 33 {+-} 18% mean cortical signal loss on T2*-weighted images. In the remaining eight patients, with <5 macrophages/mm{sup 2}, there was no cortical signal loss. However, in three of these, presenting with ischemic acute tubular necrosis, a strong (42 {+-} 18%) signal drop was found in the medulla exclusively. USPIO-enhanced MR imaging can demonstrate infiltration of the kidneys by macrophages both in native and transplanted kidneys and may help to differentiate between kidney diseases. (orig.)

  13. ISDoT: in situ decellularization of tissues for high-resolution imaging and proteomic analysis of native extracellular matrix.

    Science.gov (United States)

    Mayorca-Guiliani, Alejandro E; Madsen, Chris D; Cox, Thomas R; Horton, Edward R; Venning, Freja A; Erler, Janine T

    2017-07-01

    The extracellular matrix (ECM) is a master regulator of cellular phenotype and behavior. It has a crucial role in both normal tissue homeostasis and disease pathology. Here we present a fast and efficient approach to enhance the study of ECM composition and structure. Termed in situ decellularization of tissues (ISDoT), it allows whole organs to be decellularized, leaving native ECM architecture intact. These three-dimensional decellularized tissues can be studied using high-resolution fluorescence and second harmonic imaging, and can be used for quantitative proteomic interrogation of the ECM. Our method is superior to other methods tested in its ability to preserve the structural integrity of the ECM, facilitate high-resolution imaging and quantitatively detect ECM proteins. In particular, we performed high-resolution sub-micron imaging of matrix topography in normal tissue and over the course of primary tumor development and progression to metastasis in mice, providing the first detailed imaging of the metastatic niche. These data show that cancer-driven ECM remodeling is organ specific, and that it is accompanied by comprehensive changes in ECM composition and topological structure. We also describe differing patterns of basement-membrane organization surrounding different types of blood vessels in healthy and diseased tissues. The ISDoT procedure allows for the study of native ECM structure under normal and pathological conditions in unprecedented detail.

  14. Automatic target classification of man-made objects in synthetic aperture radar images using Gabor wavelet and neural network

    Science.gov (United States)

    Vasuki, Perumal; Roomi, S. Mohamed Mansoor

    2013-01-01

    Processing of synthetic aperture radar (SAR) images has led to the development of automatic target classification approaches. These approaches help to classify individual and mass military ground vehicles. This work aims to develop an automatic target classification technique to classify military targets like truck/tank/armored car/cannon/bulldozer. The proposed method consists of three stages via preprocessing, feature extraction, and neural network (NN). The first stage removes speckle noise in a SAR image by the identified frost filter and enhances the image by histogram equalization. The second stage uses a Gabor wavelet to extract the image features. The third stage classifies the target by an NN classifier using image features. The proposed work performs better than its counterparts, like K-nearest neighbor (KNN). The proposed work performs better on databases like moving and stationary target acquisition and recognition against the earlier methods by KNN.

  15. A large dataset of synthetic SEM images of powder materials and their ground truth 3D structures.

    Science.gov (United States)

    DeCost, Brian L; Holm, Elizabeth A

    2016-12-01

    This data article presents a data set comprised of 2048 synthetic scanning electron microscope (SEM) images of powder materials and descriptions of the corresponding 3D structures that they represent. These images were created using open source rendering software, and the generating scripts are included with the data set. Eight particle size distributions are represented with 256 independent images from each. The particle size distributions are relatively similar to each other, so that the dataset offers a useful benchmark to assess the fidelity of image analysis techniques. The characteristics of the PSDs and the resulting images are described and analyzed in more detail in the research article "Characterizing powder materials using keypoint-based computer vision methods" (B.L. DeCost, E.A. Holm, 2016) [1]. These data are freely available in a Mendeley Data archive "A large dataset of synthetic SEM images of powder materials and their ground truth 3D structures" (B.L. DeCost, E.A. Holm, 2016) located at http://dx.doi.org/10.17632/tj4syyj9mr.1[2] for any academic, educational, or research purposes.

  16. A large dataset of synthetic SEM images of powder materials and their ground truth 3D structures

    Directory of Open Access Journals (Sweden)

    Brian L. DeCost

    2016-12-01

    Full Text Available This data article presents a data set comprised of 2048 synthetic scanning electron microscope (SEM images of powder materials and descriptions of the corresponding 3D structures that they represent. These images were created using open source rendering software, and the generating scripts are included with the data set. Eight particle size distributions are represented with 256 independent images from each. The particle size distributions are relatively similar to each other, so that the dataset offers a useful benchmark to assess the fidelity of image analysis techniques. The characteristics of the PSDs and the resulting images are described and analyzed in more detail in the research article “Characterizing powder materials using keypoint-based computer vision methods” (B.L. DeCost, E.A. Holm, 2016 [1]. These data are freely available in a Mendeley Data archive “A large dataset of synthetic SEM images of powder materials and their ground truth 3D structures” (B.L. DeCost, E.A. Holm, 2016 located at http://dx.doi.org/10.17632/tj4syyj9mr.1 [2] for any academic, educational, or research purposes.

  17. Synthetic environments

    Science.gov (United States)

    Lukes, George E.; Cain, Joel M.

    1996-02-01

    The Advanced Distributed Simulation (ADS) Synthetic Environments Program seeks to create robust virtual worlds from operational terrain and environmental data sources of sufficient fidelity and currency to interact with the real world. While some applications can be met by direct exploitation of standard digital terrain data, more demanding applications -- particularly those support operations 'close to the ground' -- are well-served by emerging capabilities for 'value-adding' by the user working with controlled imagery. For users to rigorously refine and exploit controlled imagery within functionally different workstations they must have a shared framework to allow interoperability within and between these environments in terms of passing image and object coordinates and other information using a variety of validated sensor models. The Synthetic Environments Program is now being expanded to address rapid construction of virtual worlds with research initiatives in digital mapping, softcopy workstations, and cartographic image understanding. The Synthetic Environments Program is also participating in a joint initiative for a sensor model applications programer's interface (API) to ensure that a common controlled imagery exploitation framework is available to all researchers, developers and users. This presentation provides an introduction to ADS and the associated requirements for synthetic environments to support synthetic theaters of war. It provides a technical rationale for exploring applications of image understanding technology to automated cartography in support of ADS and related programs benefitting from automated analysis of mapping, earth resources and reconnaissance imagery. And it provides an overview and status of the joint initiative for a sensor model API.

  18. 300 GHz Imaging System with 8 Meter Stand-off Distance and One-Dimensional Synthetic Image Reconstruction for Remote Detection of Material Defects

    DEFF Research Database (Denmark)

    Keil, Andreas; Peuser, Jörn; Loeffler, Torsten

    2011-01-01

    An active stand-off imaging system operating at 230–320 GHz is presented. Imaging is achieved by combining a line array consisting of 8 sources and 16 detectors with a scanning cylindrical mirror system. The stand-off distance is 8 meters and the effective aperture of the system is 0.5 meters by 0.......5 meters. Range and intensity information of the object are obtained using an active FMCW (frequency modulated continuous wave) radar principle. Data acquisition time for one line is as short as 1 ms. Synthetic image reconstruction is achieved in real-time by an embedded GPU (Graphical Processing Unit...

  19. ISDoT: in situ decellularization of tissues for high-resolution imaging and proteomic analysis of native extracellular matrix

    DEFF Research Database (Denmark)

    Mayorca-Guiliani, Alejandro E.; Madsen, Chris D.; Cox, Thomas R.

    2017-01-01

    decellularization of tissues (ISDoT), it allows whole organs to be decellularized, leaving native ECM architecture intact. These three-dimensional decellularized tissues can be studied using high-resolution fluorescence and second harmonic imaging, and can be used for quantitative proteomic interrogation of the ECM....... Our method is superior to other methods tested in its ability to preserve the structural integrity of the ECM, facilitate high-resolution imaging and quantitatively detect ECM proteins. In particular, we performed high-resolution sub-micron imaging of matrix topography in normal tissue and over......The extracellular matrix (ECM) is a master regulator of cellular phenotype and behavior. It has a crucial role in both normal tissue homeostasis and disease pathology. Here we present a fast and efficient approach to enhance the study of ECM composition and structure. Termed in situ...

  20. Inverse synthetic aperture radar imaging of targets with complex motion based on the local polynomial ambiguity function

    Science.gov (United States)

    Lv, Qian; Su, Tao; Zheng, Jibin

    2016-01-01

    In inverse synthetic aperture radar (ISAR) imaging of targets with complex motion, the azimuth echoes have to be modeled as multicomponent cubic phase signals (CPSs) after motion compensation. For the CPS model, the chirp rate and the quadratic chirp rate deteriorate the ISAR image quality due to the Doppler frequency shift; thus, an effective parameter estimation algorithm is required. This paper focuses on a parameter estimation algorithm for multicomponent CPSs based on the local polynomial ambiguity function (LPAF), which is simple and can be easily implemented via the complex multiplication and fast Fourier transform. Compared with the existing parameter estimation algorithm for CPS, the proposed algorithm can achieve a better compromise between performance and computational complexity. Then, the high-quality ISAR image can be obtained by the proposed LPAF-based ISAR imaging algorithm. The results of the simulated data demonstrate the effectiveness of the proposed algorithm.

  1. Semi-synthesis of biologically active nisin hybrids composed of the native lanthionine ABC-fragment and a cross-stapled synthetic DE-fragment

    NARCIS (Netherlands)

    Slootweg, Jack C.; Peters, Nienke; Quarles Van Ufford, H. C.; Breukink, Eefjan; Liskamp, Rob M J; Rijkers, Dirk T S

    2014-01-01

    The antimicrobial peptide nisin is a promising template for designing novel peptide-based antibiotics to improve its drug-like properties. First steps in that direction represent the synthesis of hybrid nisin derivatives that contain a native nisin ABC-part and synthesized cross-stapled DE-ring frag

  2. Change detection from synthetic aperture radar images based on neighborhood-based ratio and extreme learning machine

    Science.gov (United States)

    Gao, Feng; Dong, Junyu; Li, Bo; Xu, Qizhi; Xie, Cui

    2016-10-01

    Change detection is of high practical value to hazard assessment, crop growth monitoring, and urban sprawl detection. A synthetic aperture radar (SAR) image is the ideal information source for performing change detection since it is independent of atmospheric and sunlight conditions. Existing SAR image change detection methods usually generate a difference image (DI) first and use clustering methods to classify the pixels of DI into changed class and unchanged class. Some useful information may get lost in the DI generation process. This paper proposed an SAR image change detection method based on neighborhood-based ratio (NR) and extreme learning machine (ELM). NR operator is utilized for obtaining some interested pixels that have high probability of being changed or unchanged. Then, image patches centered at these pixels are generated, and ELM is employed to train a model by using these patches. Finally, pixels in both original SAR images are classified by the pretrained ELM model. The preclassification result and the ELM classification result are combined to form the final change map. The experimental results obtained on three real SAR image datasets and one simulated dataset show that the proposed method is robust to speckle noise and is effective to detect change information among multitemporal SAR images.

  3. AFM Imaging of RGD Presenting Synthetic Extracellular Matrix using Gold Nanoparticles

    Science.gov (United States)

    Cell-interactive polymers have been widely used as synthetic extracellular matrices (sECM) to regulate cell function and promote tissue regeneration. Although it is known that adhesion ligand density and distribution influence the proliferation and differentiation of various cell types, currently a...

  4. Testing for Multivariate Normality in Mass Spectrometry Imaging Data: A Robust Statistical Approach for Clustering Evaluation and the Generation of Synthetic Mass Spectrometry Imaging Data Sets.

    Science.gov (United States)

    Dexter, Alex; Race, Alan M; Styles, Iain B; Bunch, Josephine

    2016-11-15

    Spatial clustering is a powerful tool in mass spectrometry imaging (MSI) and has been demonstrated to be capable of differentiating tumor types, visualizing intratumor heterogeneity, and segmenting anatomical structures. Several clustering methods have been applied to mass spectrometry imaging data, but a principled comparison and evaluation of different clustering techniques presents a significant challenge. We propose that testing whether the data has a multivariate normal distribution within clusters can be used to evaluate the performance when using algorithms that assume normality in the data, such as k-means clustering. In cases where clustering has been performed using the cosine distance, conversion of the data to polar coordinates prior to normality testing should be performed to ensure normality is tested in the correct coordinate system. In addition to these evaluations of internal consistency, we demonstrate that the multivariate normal distribution can then be used as a basis for statistical modeling of MSI data. This allows the generation of synthetic MSI data sets with known ground truth, providing a means of external clustering evaluation. To demonstrate this, reference data from seven anatomical regions of an MSI image of a coronal section of mouse brain were modeled. From this, a set of synthetic data based on this model was generated. Results of r(2) fitting of the chi-squared quantile-quantile plots on the seven anatomical regions confirmed that the data acquired from each spatial region was found to be closer to normally distributed in polar space than in Euclidean. Finally, principal component analysis was applied to a single data set that included synthetic and real data. No significant differences were found between the two data types, indicating the suitability of these methods for generating realistic synthetic data.

  5. Advanced 3-D Ultrasound Imaging: 3-D Synthetic Aperture Imaging using Fully Addressed and Row-Column Addressed 2-D Transducer Arrays

    DEFF Research Database (Denmark)

    Bouzari, Hamed

    with transducer arrays using this addressing scheme, when integrated into probe handles. For that reason, two in-house prototyped 62+62 row-column addressed 2-D array transducer probes were manufactured using capacitive micromachined ultrasonic transducer (CMUT) and piezoelectric transducer (PZT) technology...... in many clinical applications. Real-time 3-D ultrasound imaging is still not as widespread in use in the clinics as 2-D ultrasound imaging. Two limiting factors have traditionally been the low image quality as well as low volume rate achievable with a 2-D transducer array using the conventional 3-D...... and measurements with the ultrasound research scanner SARUS and a 3.8 MHz 1024 element 2-D transducer array. In all investigations, 3-D synthetic aperture imaging achieved a better resolution, lower side-lobes, higher contrast, and better signal to noise ratio than parallel beamforming. This is achieved partly...

  6. Review of Ship Surveillance Technologies Based on High-Resolution Wide-Swath Synthetic Aperture Radar Imaging

    Directory of Open Access Journals (Sweden)

    Xing Xiang-wei

    2015-02-01

    Full Text Available Synthetic Aperture Radar (SAR is widely used in ship surveillance. High-Resolution Wide-Swath (HRWS SAR data are simultaneously collected, which introduces challenges and offers new research opportunities. SAR-based ship-surveillance technologies and the performance requirements of SAR systems are reviewed and summarized. Furthermore, the characteristics of HRWS SAR imaging and ship surveillance technologies are considered in tandem, and preliminary research results on ship detection, feature extraction, and classification are discussed. Finally, we point out issues to be addressed in future work.

  7. Detection of linear features in synthetic-aperture radar images by use of the localized Radon transform and prior information.

    Science.gov (United States)

    Onana, Vincent-de-Paul; Trouvé, Emmanuel; Mauris, Gilles; Rudant, Jean-Paul; Tonyé, Emmanuel

    2004-01-10

    A new linear-features detection method is proposed for extracting straight edges and lines in synthetic-aperture radar images. This method is based on the localized Radon transform, which produces geometrical integrals along straight lines. In the transformed domain, linear features have a specific signature: They appear as strongly contrasted structures, which are easier to extract with the conventional ratio edge detector. The proposed method is dedicated to applications such as geographical map updating for which prior information (approximate length and orientation of features) is available. Experimental results show the method's robustness with respect to poor radiometric contrast and hidden parts and its complementarity to conventional pixel-by-pixel approaches.

  8. In vivo demonstration of reflection artifact reduction in photoacoustic imaging using synthetic aperture photoacoustic-guided focused ultrasound (PAFUSion).

    Science.gov (United States)

    Singh, Mithun Kuniyil Ajith; Jaeger, Michael; Frenz, Martin; Steenbergen, Wiendelt

    2016-08-01

    Reflection artifacts caused by acoustic inhomogeneities are a critical problem in epi-mode biomedical photoacoustic imaging. High light fluence beneath the probe results in photoacoustic transients, which propagate into the tissue and reflect back from echogenic structures. These reflection artifacts cause problems in image interpretation and significantly impact the contrast and imaging depth. We recently proposed a method called PAFUSion (Photoacoustic-guided focused ultrasound) to identify such reflection artifacts in photoacoustic imaging. In its initial version, PAFUSion mimics the inward-travelling wavefield from small blood vessel-like PA sources by applying ultrasound pulses focused towards these sources, and thus provides a way to identify the resulting reflection artifacts. In this work, we demonstrate reduction of reflection artifacts in phantoms and in vivo measurements on human volunteers. In view of the spatially distributed PA sources that are found in clinical applications, we implemented an improved version of PAFUSion where photoacoustic signals are backpropagated to imitate the inward travelling wavefield and thus the reflection artifacts. The backpropagation is performed in a synthetic way based on the pulse-echo acquisitions after transmission on each single element of the transducer array. The results provide a direct confirmation that reflection artifacts are prominent in clinical epi-photoacoustic imaging, and that PAFUSion can strongly reduce these artifacts to improve deep-tissue photoacoustic imaging.

  9. Kurtosis-based estimation of cross-range scaling factor for high-resolution inverse synthetic aperture radar imaging

    Science.gov (United States)

    Phan, An; Ng, Brian; Tran, Hai-Tan

    2016-07-01

    In automatic target recognition systems based on the use of inverse synthetic aperture radar (ISAR) images, it is essential to obtain unbiased and accurate scaled two-dimensional target images in the range-cross range domain. To accomplish this, the modulus of the target effective rotation vector, which is generally unknown for noncooperative targets, must be estimated. This letter proposes an efficient method for estimating the cross-range scaling factor and significantly improving cross-range resolution based on the second-order local polynomial Fourier transform. The estimation requires solving a series of one-dimensional optimizations of a kurtosis objective. Simulations show the proposed approach to be effective and able to accurately estimate the scaling factor in the presence of noise.

  10. Adaptive method of speckle reduction based on curvelet transform and thresholding neural network in synthetic aperture radar images

    Science.gov (United States)

    Zakeri, Fatemeh; Zoej, Mohammad Javad Valadan

    2015-01-01

    Because of the effect of speckles in synthetic aperture radar (SAR) images, its reduction has been considered by many researchers to obtain reliable information. This paper proposes a method based on the curvelet transform to reduce speckles in SAR images. This study is based on the thresholding neural network (TNN) technique, which has been previously used in wavelet transformation. In addition, an adaptive learning TNN with remarkable time saving was introduced. Comparing the obtained results from the method with conventional speckle filters such as Lee, Kuan, Frost, and Gamma filters, curvelet-based, nonadaptive despeckling, wavelet-based TNN despeckling, and curvelet-based particle swarm optimization show better achievement of the proposed algorithm. For instance, noise mean value, noise standard deviation, mean square difference, equivalent number of looks, and β (an edge-preserving criterion) improved 2%, 9%, 21%, 35%, and 9%, respectively.

  11. Use of synthetic peptides to represent surface-exposed epitopes defined by neutralizing dengue complex- and flavivirus group-reactive monoclonal antibodies on the native dengue type-2 virus envelope glycoprotein.

    Science.gov (United States)

    Falconar, Andrew K I

    2008-07-01

    The reactions of neutralizing monoclonal antibodies (mAbs) that defined dengue virus (DENV) complex, flavivirus subgroup or group neutralizing epitopes were tested against synthetic peptide sequences from domains I, II and III of the envelope (E) glycoproteins of different DENV-2 genotypes/strains. The DENV complex-reactive mAb identified the surface-exposed 304-GKFKV/IVKEIA-313 peptides and the DENV complex-conserved 393-KKGSSIGQ/KM-401 peptides in domain III, which were located adjacently in the native glycoprotein. Both flavivirus group-reactive mAbs reacted most strongly with fusion sequence peptides from domain II when they contained a cysteine (C) by glycine (G) substitution (underlined) (101-WGNGGGLFG-109) to represent the native rotated C side chain. The 393-401 sequence represents a newly identified epitope, present as a highly flexible coil located between the 385 and 393 cell-binding sequence and the 401 and 413 sequence involved in the E glycoprotein homo-trimer formation. The 101-109 sequence containing 105-C by G substitution and the 393-401 sequence are good candidates for diagnostic assays and cross-protection experiments.

  12. Manmade target extraction based on multistage decision and its application for change detection in polarimetric synthetic aperture radar image

    Science.gov (United States)

    Cong, Runmin; Han, Ping; Li, Chongyi; He, Jiaji; Zhang, Zaiji

    2016-09-01

    Targets of interest are different in various applications in which manmade targets, such as aircraft, ships, and buildings, are given more attention. Manmade target extraction methods using synthetic aperture radar (SAR) images are designed in response to various demands, which include civil uses, business purposes, and military industries. This plays an increasingly vital role in monitoring, military reconnaissance, and precision strikes. Achieving accurate and complete results through traditional methods is becoming more challenging because of the scattered complexity of polarization in polarimetric synthetic aperture radar (PolSAR) image. A multistage decision-based method is proposed composed of power decision, dominant scattering mechanism decision, and reflection symmetry decision. In addition, the theories of polarimetric contrast enhancement, generalized Y decomposition, and maximum eigenvalue ratio are applied to assist the decision. Fully PolSAR data are adopted to evaluate and verify the approach. Experimental results show that the method can achieve an effective result with a lower false alarm rate and clear contours. Finally, on this basis, a universal framework of change detection for manmade targets is presented as an application of our method. Two sets of measured data are also used to evaluate and verify the effectiveness of the change-detection algorithm.

  13. Study of Effects of Flat Surface Assumption to Synthetic Aperture Radar Time-domain Algorithms Imaging Quality

    Directory of Open Access Journals (Sweden)

    Lin Shi-bin

    2012-08-01

    Full Text Available Time-domain algorithms have great application prospect in Ultra Wide Band Synthetic Aperture Radar (UWB SAR imaging for its advantages such as perfect focusing and perfect motion compensation. We could adopt the flat surface assumption to simplify the imaging geometric model, when undulating terrain is imaged using time-domain algorithms. Nevertheless, the flat surface assumption leads to geometric errors, thereby affecting the imaging results. This paper studies the effects of this assumption on time-domain imaging algorithms, points out that it leads to position offset problem in the case of linear aperture, and it even leads to target defocusing problem in the case of non-linear aperture. The expression of position offset is given in this paper, as well as the restriction of the maximal offset of the non-linear aperture and the maximum elevation of the area in order to focus the targets. The conclusions are validated by simulated data, which is processed by one kind of time-domain algorithms, namely Back Projection (BP algorithm.

  14. Inspection of copper canisters for spent nuclear fuel by means of ultrasound. Nonlinear acoustics, synthetic aperture imaging

    Energy Technology Data Exchange (ETDEWEB)

    Lingvall, Fredrik; Ping Wu; Stepinski, Tadeusz [Uppsala Univ., (Sweden). Dept. of Materials Science

    2003-03-01

    This report contains results concerning inspection of copper canisters for spent nuclear fuel by means of ultrasound obtained at Signals and Systems, Uppsala University in year 2001/2002. The first chapter presents results of an investigation of a new method for synthetic aperture imaging. The new method presented here takes the form of a 2D filter based on minimum mean squared error (MMSE) criteria. The filter, which varies with the target position in two dimensions includes information about spatial impulse response (SIR) of the imaging system. Spatial resolution of the MMSE method is investigated and compared experimentally to that of the classical SAFT and phased array imaging. It is shown that the resolution of the MMSE algorithm, evaluated for imaging immersed copper specimen is superior to that observed for the two above-mentioned methods. Extended experimental and theoretical research concerning the potential of nonlinear waves and material harmonic imaging is presented in the second chapter. An experimental work is presented that was conducted using the RITEC RAM-5000 ultrasonic system capable of providing a high power tone-burst output. A new method for simulation of nonlinear acoustic waves that is a combination of the angular spectrum approach and the Burger's equation is also presented. This method was used for simulating nonlinear elastic waves radiated by the annular transducer that was used in the experiments.

  15. Noise Filtering in the Synthetic Transmit Aperture Imaging by Decomposition of the Time Reversal Operator: Application to Flaw Detection in Coarse-grained Stainless Steels

    Science.gov (United States)

    Villaverde, Eduardo Rigoberto Lopez; Robert, Sebastien; Prada, Claire

    In the present work, the Synthetic Transmit Aperture (STA) imaging is applied on coarse grained steels using a contact phased-array probe. In order to reduce the noise introduced by the heterogeneous structure, as well as artifacts due to surface guided waves, the Decomposition of the Time Reversal Operator method is performed before calculating STA images.

  16. Road Extraction and Network Building from Synthetic Aperture Radar Images using A-Priori Information

    NARCIS (Netherlands)

    Dekker, R.J.

    2008-01-01

    This paper describes a method for the extraction of road networks from radar images. Three phases can be distinguished: (1) detection of road lines, (2) network building, and (3) network fusion. The method has been demonstrated on two radar images, one urban and one rural. Despite the differences,

  17. Road Extraction and Network Building from Synthetic Aperture Radar Images using A-Priori Information

    NARCIS (Netherlands)

    Dekker, R.J.

    2008-01-01

    This paper describes a method for the extraction of road networks from radar images. Three phases can be distinguished: (1) detection of road lines, (2) network building, and (3) network fusion. The method has been demonstrated on two radar images, one urban and one rural. Despite the differences, t

  18. Synthetic Brainbows

    KAUST Repository

    Wan, Y.

    2013-06-01

    Brainbow is a genetic engineering technique that randomly colorizes cells. Biological samples processed with this technique and imaged with confocal microscopy have distinctive colors for individual cells. Complex cellular structures can then be easily visualized. However, the complexity of the Brainbow technique limits its applications. In practice, most confocal microscopy scans use different florescence staining with typically at most three distinct cellular structures. These structures are often packed and obscure each other in rendered images making analysis difficult. In this paper, we leverage a process known as GPU framebuffer feedback loops to synthesize Brainbow-like images. In addition, we incorporate ID shuffing and Monte-Carlo sampling into our technique, so that it can be applied to single-channel confocal microscopy data. The synthesized Brainbow images are presented to domain experts with positive feedback. A user survey demonstrates that our synthetic Brainbow technique improves visualizations of volume data with complex structures for biologists.

  19. Method for In-vivo Synthetic Aperture B-flow Imaging

    DEFF Research Database (Denmark)

    Jensen, Jørgen Arendt

    2004-01-01

    -pass filters designed by the Remez exchange algorithm, have been used for the B-flow processing. The image is displayed after each set of emissions yielding 375 frames per second. Both the flow in the carotid artery and the jugular vein can be seen along with an indication of the acceleration and spatial....... Data is acquired over a number of pulse emissions, where a set of elements synthesizes a spherical wave and the received signal on all elements are acquired. The sequence is repeated and a full new image can always be formed from the last set of emissions, thus making the frame rate very high. The data...... is continuously available at all places in the image and any kind of echo canceling filter can therefore be used without the usual initialization problems. The B-flow images are then formed by displaying the gray level image after echo canceling. A fast moving scatterer will give a bright echo and slower moving...

  20. Terahertz Wide-Angle Imaging and Analysis on Plane-wave Criteria Based on Inverse Synthetic Aperture Techniques

    Science.gov (United States)

    Gao, Jing Kun; Qin, Yu Liang; Deng, Bin; Wang, Hong Qiang; Li, Jin; Li, Xiang

    2016-04-01

    This paper presents two parts of work around terahertz imaging applications. The first part aims at solving the problems occurred with the increasing of the rotation angle. To compensate for the nonlinearity of terahertz radar systems, a calibration signal acquired from a bright target is always used. Generally, this compensation inserts an extra linear phase term in the intermediate frequency (IF) echo signal which is not expected in large-rotation angle imaging applications. We carried out a detailed theoretical analysis on this problem, and a minimum entropy criterion was employed to estimate and compensate for the linear-phase errors. In the second part, the effects of spherical wave on terahertz inverse synthetic aperture imaging are analyzed. Analytic criteria of plane-wave approximation were derived in the cases of different rotation angles. Experimental results of corner reflectors and an aircraft model based on a 330-GHz linear frequency-modulated continuous wave (LFMCW) radar system validated the necessity and effectiveness of the proposed compensation. By comparing the experimental images obtained under plane-wave assumption and spherical-wave correction, it also showed to be highly consistent with the analytic criteria we derived.

  1. Analysis of polarimetric synthetic aperture radar and passive visible light polarimetric imaging data fusion for remote sensing applications

    Science.gov (United States)

    Maitra, Sanjit

    The recent launch of spaceborne (TerraSAR-X, RADARSAT-2, ALOS-PALSAR, RISAT) and airborne (SIRC, AIRSAR, UAVSAR, PISAR) polarimetric radar sensors, with capability of imaging through day and night in almost all weather conditions, has made polarimetric synthetic aperture radar (PolSAR) image interpretation and analysis an active area of research. PolSAR image classification is sensitive to object orientation and scattering properties. In recent years, significant work has been done in many areas including agriculture, forestry, oceanography, geology, terrain analysis. Visible light passive polarimetric imaging has also emerged as a powerful tool in remote sensing for enhanced information extraction. The intensity image provides information on materials in the scene while polarization measurements capture surface features, roughness, and shading, often uncorrelated with the intensity image. Advantages of visible light polarimetric imaging include high dynamic range of polarimetric signatures and being comparatively straightforward to build and calibrate. This research is about characterization and analysis of the basic scattering mechanisms for information fusion between PolSAR and passive visible light polarimetric imaging. Relationships between these two modes of imaging are established using laboratory measurements and image simulations using the Digital Image and Remote Sensing Image Generation (DIRSIG) tool. A novel low cost laboratory based S-band (2.4GHz) PolSAR instrument is developed that is capable of capturing 4 channel fully polarimetric SAR image data. Simple radar targets are formed and system calibration is performed in terms of radar cross-section. Experimental measurements are done using combination of the PolSAR instrument with visible light polarimetric imager for scenes capturing basic scattering mechanisms for phenomenology studies. The three major scattering mechanisms studied in this research include single, double and multiple bounce. Single

  2. K-space model of motion artifacts in synthetic transmit aperture ultrasound imaging

    DEFF Research Database (Denmark)

    Nikolov, Svetoslav; Jensen, Jørgen Arendt

    2003-01-01

    and leads to distortions in the image. In order to develop motion compensation and/or velocity estimation algorithms a thorough and intuitive understanding of the nature of motion artifacts is needed. This paper proposes a simple 2D broad band model for STA images, based on the acquisition procedure...... resolution image as a sum of rotated PSFs of a single LRI. The approximation is validated with a Field II simulation. The model predicts and explains the motion artifacts, and gives an intuitive feeling of what would happen for different velocities....

  3. The Effect of Synthetic Aperture Radar Image Resolution on Target Discrimination

    Science.gov (United States)

    2010-03-01

    resolutions. 50 Figure 5.16: AUROC versus resolution in the x and y directions for the size features for image filter degradation. 51 Figure 5.17...AUROC versus resolution in the x and y directions for the mass feature for image filter degradation. 52 Figure 5.18: AUROC versus resolution in the x and...y directions for the diameter feature for image filter degradation. 53 Figure 5.19: AUROC versus resolution in the x and y directions for the

  4. Terahertz inverse synthetic aperture radar (ISAR) imaging with a quantum cascade laser transmitter.

    Science.gov (United States)

    Danylov, Andriy A; Goyette, Thomas M; Waldman, Jerry; Coulombe, Michael J; Gatesman, Andrew J; Giles, Robert H; Qian, Xifeng; Chandrayan, Neelima; Vangala, Shivashankar; Termkoa, Krongtip; Goodhue, William D; Nixon, William E

    2010-07-19

    A coherent transceiver using a THz quantum cascade (TQCL) laser as the transmitter and an optically pumped molecular laser as the local oscillator has been used, with a pair of Schottky diode mixers in the receiver and reference channels, to acquire high-resolution images of fully illuminated targets, including scale models and concealed objects. Phase stability of the received signal, sufficient to allow coherent image processing of the rotating target (in azimuth and elevation), was obtained by frequency-locking the TQCL to the free-running, highly stable optically pumped molecular laser. While the range to the target was limited by the available TQCL power (several hundred microwatts) and reasonably strong indoor atmospheric attenuation at 2.408 THz, the coherence length of the TQCL transmitter will allow coherent imaging over distances up to several hundred meters. Image data obtained with the system is presented.

  5. Multi-spectral synthetic image generation for ground vehicle identification training

    Science.gov (United States)

    May, Christopher M.; Pinto, Neil A.; Sanders, Jeffrey S.

    2016-05-01

    There is a ubiquitous and never ending need in the US armed forces for training materials that provide the warfighter with the skills needed to differentiate between friendly and enemy forces on the battlefield. The current state of the art in battlefield identification training is the Recognition of Combat Vehicles (ROC-V) tool created and maintained by the Communications - Electronics Research, Development and Engineering Center Night Vision and Electronic Sensors Directorate (CERDEC NVESD). The ROC-V training package utilizes measured visual and thermal imagery to train soldiers about the critical visual and thermal cues needed to accurately identify modern military vehicles and combatants. This paper presents an approach to augment the existing ROC-V imagery database with synthetically generated multi-spectral imagery that will allow NVESD to provide improved training imagery at significantly lower costs.

  6. Motion error correction approach for high-resolution synthetic aperture radar imaging

    Science.gov (United States)

    Jia, Gaowei; Chang, Wenge; Li, Xiangyang

    2014-01-01

    An innovative data-based motion compensation approach is proposed for the high-resolution synthetic aperture radar (SAR). The main idea is to extract the displacements in line-of-sight direction and the range-dependent phase errors from raw data, based on an instantaneous Doppler rate estimate. The approach is implemented by a two-step process: (1) the correction of excessive range cell migration; (2) the compensation of range-dependent phase errors. Experimental results show that the proposed method is capable of producing high-resolution SAR imagery with a spatial resolution of 0.17×0.2 m2 (range×azimuth) in Ku band.

  7. Geometric ortho-rectification and generation of sigma(0) image products from multiple incidence synthetic aperture radar images

    Science.gov (United States)

    Curlander, James; Leberl, Franz; Kruse, Fred

    1992-01-01

    The results of the first phase of a cooperative effort in geometric orthorectification and generation of sigma(0) images of multiple incidence SAR images are presented. The geometric accuracy of the final image products is approximately 18 m or 1.5 pixels. A method for registering radar imagery collected from an airborne platform to an existing digital elevation model despite the effects of unmodeled variations in the flight path of the platform is demonstrated. The results indicate the requirements for a more detailed digital elevation model.

  8. Mapping of sea ice and measurement of its drift using aircraft synthetic aperture radar images

    Science.gov (United States)

    Leberl, F.; Bryan, M. L.; Elachi, C.; Farr, T.; Campbell, W.

    1979-01-01

    Side-looking radar images of Arctic sea ice were obtained as part of the Arctic Ice Dynamics Joint Experiment. Repetitive coverages of a test site in the Arctic were used to measure sea ice drift, employing single images and blocks of overlapping radar image strips; the images were used in conjunction with data from the aircraft inertial navigation and altimeter. Also, independently measured, accurate positions of a number of ground control points were available. Initial tests of the method were carried out with repeated coverages of a land area on the Alaska coast (Prudhoe). Absolute accuracies achieved were essentially limited by the accuracy of the inertial navigation data. Errors of drift measurements were found to be about + or - 2.5 km. Relative accuracy is higher; its limits are set by the radar image geometry and the definition of identical features in sequential images. The drift of adjacent ice features with respect to one another could be determined with errors of less than + or - 0.2 km.

  9. Synthetic Covalently Linked Dimeric Form of H2 Relaxin Retains Native RXFP1 Activity and Has Improved In Vitro Serum Stability

    Directory of Open Access Journals (Sweden)

    Vinojini B. Nair

    2015-01-01

    Full Text Available Human (H2 relaxin is a two-chain peptide member of the insulin superfamily and possesses potent pleiotropic roles including regulation of connective tissue remodeling and systemic and renal vasodilation. These effects are mediated through interaction with its cognate G-protein-coupled receptor, RXFP1. H2 relaxin recently passed Phase III clinical trials for the treatment of congestive heart failure. However, its in vivo half-life is short due to its susceptibility to proteolytic degradation and renal clearance. To increase its residence time, a covalent dimer of H2 relaxin was designed and assembled through solid phase synthesis of the two chains, including a judiciously monoalkyne sited B-chain, followed by their combination through regioselective disulfide bond formation. Use of a bisazido PEG7 linker and “click” chemistry afforded a dimeric H2 relaxin with its active site structurally unhindered. The resulting peptide possessed a similar secondary structure to the native monomeric H2 relaxin and bound to and activated RXFP1 equally well. It had fewer propensities to activate RXFP2, the receptor for the related insulin-like peptide 3. In human serum, the dimer had a modestly increased half-life compared to the monomeric H2 relaxin suggesting that additional oligomerization may be a viable strategy for producing longer acting variants of H2 relaxin.

  10. Spatio-temporal encoding using narrow-band linear frequency modulated signals in synthetic aperture ultrasound imaging

    DEFF Research Database (Denmark)

    Gran, Fredrik; Jensen, Jørgen Arendt

    2005-01-01

    In this paper a method for spatio-temporal encoding is presented for synthetic transmit aperture ultrasound imaging (STA). The purpose is to excite several transmitters at the same time in order to transmit more acoustic energy in every single transmission. When increasing the transmitted acoustic...... energy, the signal to noise ratio will increase. However, to focus the data properly using the STA approach, the transmitters have to be separated from each other. This is done by dividing the available spectrum into several subbands with a small overlap. Separating different transmitters can be done....... The method was tested using the experimental ultrasound scanner RASMUS and evaluated using a reference setup with a linear FM excitation waveform and STA beamforming. The point spread function (PSF) was measured on a wire phantom in water. A wire phantom with an attenuating medium was also measured, where...

  11. Bone dosimetry using synthetic images to represent trabecular bones of five regions of the human body

    Energy Technology Data Exchange (ETDEWEB)

    Lima Filho, Jose de M. [Instituto Federal de Educacao, Ciencia e Tecnologia de Pernambuco (IFPE), Recife, PE (Brazil); Vieira, Jose W. [Escola Politecnica de Pernambuco (POLI). Universidade de Pernambuco (UPE), Recife, PE (Brazil); Lima, Vanildo J. de M., E-mail: vjr@ufpe.br [Departamento de Anatomia. Universidade Federal de Pernambuco (UFPE), Recife, PE (Brazil); Lima, Lindeval F., E-mail: lindeval@dmat.ufrr.br [Departamento de Matematica (DMAT). Universidade Federal de Roraima (UFRR), Boa Vista, RR (Brazil); Lima, Fernando R.A., E-mail: falima@cnen.gov.br [Centro Regional de Ciencias Nucleares (CRCN/NE-CNEN-PE), Recife, PE (Brazil); Vasconcelos, Wagner E. de [Departamento de Energia Nuclear (DEN). Universidade Federal de Pernambuco (UFPE), Recife, PE (Brazil)

    2011-07-01

    One of the greatest challenges in numerical dosimetry of ionizing radiation is to estimate the absorbed dose by bone tissue in the human body. The bone tissues of greater radiosensitivity are the red bone marrow (RBM), that consist of the hematopoietic cells, located within the trabecular bones, and the bone surface cells (BSC), called osteogenic cells. The report 70 of the ICRP lists five spongiosa regions with their respective volume percent of trabecular bone: ribs (also contemplating the clavicles and sternum), spine, long bones, pelvis and skull (also contemplating mandible). The Grupo de Pesquisa em Dosimetria Numerica (GDN/CNPq) has been built exposure computational models (ECMs) based on voxel phantoms and EGSnrc Monte Carlo code. To estimate the energy deposited in the RBM and in the BSC of a phantom, the GDN/CNPq has used a method based on micro-CT images of the five trabecular regions mentioned above. These images were provided by other research institutes and were obtained from scan of bone samples of adult. Here is the greatest difficulty in reproducing this method: besides the need for bone images of real people with micrometer resolution, the distribution of bone marrow in the human body, according to ICRP 70, varies with age. This article presents some proposals of the GDN/CNPQ for replacing in the ECMs the micro-CT images by images synthesized by the computer, based on Monte Carlo sampling. (author)

  12. Integration of differential global positioning system with ultrawideband synthetic aperture radar for forward imaging

    Science.gov (United States)

    Wong, David C.; Bui, Khang; Nguyen, Lam H.; Smith, Gregory; Ton, Tuan T.

    2003-09-01

    The U.S. Army Research Laboratory (ARL), as part of a customer and mission-funded exploratory development program, has been evaluating low-frequency, ultra-wideband (UWB) imaging radar for forward imaging to support the Army's vision for increased mobility and survivability of unmanned ground vehicle missions. As part of the program to improve the radar system and imaging capability, ARL has incorporated a differential global positioning system (DGPS) for motion compensation into the radar system. The use of DGPS can greatly increase positional accuracy, thereby allowing us to improve our ability to focus better images for the detection of small targets such as plastic mines and other concealed objects buried underground. The ability of UWB radar technology to detect concealed objects could provide an important obstacle avoidance capability for robotic vehicles, which would improve the speed and maneuverability of these vehicles and consequently increase the survivability of the U.S. forces. This paper details the integration and discusses the significance of integrating a DGPS into the radar system for forward imaging. It also compares the difference between DGPS and the motion compensation data collected by the use of the original theodolite-based system.

  13. Label-free imaging of the native, living cellular nanoarchitecture using partial-wave spectroscopic microscopy.

    Science.gov (United States)

    Almassalha, Luay M; Bauer, Greta M; Chandler, John E; Gladstein, Scott; Cherkezyan, Lusik; Stypula-Cyrus, Yolanda; Weinberg, Samuel; Zhang, Di; Thusgaard Ruhoff, Peder; Roy, Hemant K; Subramanian, Hariharan; Chandel, Navdeep S; Szleifer, Igal; Backman, Vadim

    2016-10-18

    The organization of chromatin is a regulator of molecular processes including transcription, replication, and DNA repair. The structures within chromatin that regulate these processes span from the nucleosomal (10-nm) to the chromosomal (>200-nm) levels, with little known about the dynamics of chromatin structure between these scales due to a lack of quantitative imaging technique in live cells. Previous work using partial-wave spectroscopic (PWS) microscopy, a quantitative imaging technique with sensitivity to macromolecular organization between 20 and 200 nm, has shown that transformation of chromatin at these length scales is a fundamental event during carcinogenesis. As the dynamics of chromatin likely play a critical regulatory role in cellular function, it is critical to develop live-cell imaging techniques that can probe the real-time temporal behavior of the chromatin nanoarchitecture. Therefore, we developed a live-cell PWS technique that allows high-throughput, label-free study of the causal relationship between nanoscale organization and molecular function in real time. In this work, we use live-cell PWS to study the change in chromatin structure due to DNA damage and expand on the link between metabolic function and the structure of higher-order chromatin. In particular, we studied the temporal changes to chromatin during UV light exposure, show that live-cell DNA-binding dyes induce damage to chromatin within seconds, and demonstrate a direct link between higher-order chromatin structure and mitochondrial membrane potential. Because biological function is tightly paired with structure, live-cell PWS is a powerful tool to study the nanoscale structure-function relationship in live cells.

  14. Three-dimensional subsurface imaging synthetic aperture radar (3D SISAR). Final report, September 22, 1993--September 22, 1996

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1998-12-31

    The concept developed under this applied research and development contract is a novel Ground Penetrating Radar system capable of remotely detecting, analyzing, and mapping buried waste containers from a mobile platform. From the testing and analysis performed to date, the 3-D SISAR has achieved the detection, accurate location, and three-dimensional imaging of buried test objects from a stand-off geometry. Tests have demonstrated that underground objects have been located to within 0.1 meter of their actual position. This work validates that the key elements of the approach are performing as anticipated. The stand-off synthetic aperture radar (SAR) methodology has been demonstrated to be a feasible approach as a remote sensing technique. The radar sensor constructed under this project is providing adequate quality data for imaging, and the matched filters have been demonstrated to provide enhanced target detection. Additional work is on-going in the area of underground propagation and scattering phenomena to provide enhanced depth performance, as the current imaging results have been limited to a few feet of depth underground.

  15. Structural transformation of synthetic hydroxyapatite under simulated in vivo conditions studied with ATR-FTIR spectroscopic imaging

    Science.gov (United States)

    Sroka-Bartnicka, Anna; Borkowski, Leszek; Ginalska, Grazyna; Ślósarczyk, Anna; Kazarian, Sergei G.

    2017-01-01

    Hydroxyapatite and carbonate-substituted hydroxyapatite are widely used in bone tissue engineering and regenerative medicine. Both apatite materials were embedded into recently developed ceramic/polymer composites, subjected to Simulated Body Fluid (SBF) for 30 days and characterized using ATR-FTIR spectroscopic imaging to assess their behaviour and structures. The specific aim was to detect the transition phases between both types of hydroxyapatite during the test and to analyze the surface modification caused by SBF. ATR-FTIR spectroscopic imaging was successfully applied to characterise changes in the hydroxyapatite lattice due to the elastic properties of the scaffolds. It was observed that SBF treatment caused a replacement of phosphates in the lattice of non-substituted hydroxyapatite by carbonate ions. A detailed study excluded the formation of pure A type carbonate apatite. In turn, CO32- content in synthetic carbonate-substituted hydroxyapatite decreased. The usefulness of ATR-FTIR spectroscopic imaging studies in the evaluation of elastic and porous β-glucan hydroxyapatite composites has been demonstrated.

  16. Automatic Target Recognition in Synthetic Aperture Sonar Images Based on Geometrical Feature Extraction

    Directory of Open Access Journals (Sweden)

    J. Del Rio Vera

    2009-01-01

    Full Text Available This paper presents a new supervised classification approach for automated target recognition (ATR in SAS images. The recognition procedure starts with a novel segmentation stage based on the Hilbert transform. A number of geometrical features are then extracted and used to classify observed objects against a previously compiled database of target and non-target features. The proposed approach has been tested on a set of 1528 simulated images created by the NURC SIGMAS sonar model, achieving up to 95% classification accuracy.

  17. Volumetric Synthetic Aperture Imaging with a Piezoelectric 2-D Row-Column Probe

    DEFF Research Database (Denmark)

    Bouzari, Hamed; Engholm, Mathias; Christiansen, Thomas Lehrmann

    2016-01-01

    to 32 dB is measured on the beamformed images of a tissue mimicking phantom with attenuation of 0.5 dB cm−1 MHz−1, from the surface of the probe to the penetration depth of 300λ. Measured lateral resolution as Full-Width-at-Half-Maximum (FWHM) is between 4λ and 10λ for 18 % to 65 % of the penetration...... depth from the surface of the probe. The averaged contrast is 13 dB for the same range. The imaging performance assessment results may represent a reference guide for possible applications of such an array in different medical fields...

  18. Synthetic Aperture Sonar Processing with MMSE Estimation of Image Sample Values

    Science.gov (United States)

    2016-12-01

    UNCLASSIFIED/UNLIMITED 13. SUPPLEMENTARY NOTES 14. ABSTRACT MMSE (minimum mean -square error) target sample estimation using non-orthogonal basis...aspects, without a significant increase in SNR. The MMSE process creates images with new features that can be applied to image-based compensation of...orthogonal, they can still be used in a minimum  mean ‐square error (MMSE)  estimator that models the object echo as a weighted sum of the multi‐aspect basis

  19. Comparison of 3-D Synthetic Aperture Phased-Array Ultrasound Imaging and Parallel Beamforming

    DEFF Research Database (Denmark)

    Rasmussen, Morten Fischer; Jensen, Jørgen Arendt

    2014-01-01

    simulations and measurements with anultrasound research scanner and a commercially available 3.5-MHz 1024-element 2-D transducer array. To limit the probecable thickness, 256 active elements are used in transmit andreceive for both techniques. The two imaging techniques weredesigned for cardiac imaging, which......B cystic resolutionby up to 62%. The FWHM of the measured line spread func-tion (LSF) at 80mm depth showed a difference of 20% in favorof SAI. SAI reduced the cyst radius at 60mm depth by 39%in measurements. SAI improved the contrast-to-noise ratiomeasured on anechoic cysts embedded in a tissue...

  20. Implementation of synthetic aperture imaging on a hand-held device

    DEFF Research Database (Denmark)

    Hemmsen, Martin Christian; Kjeldsen, Thomas; Larsen, Lee;

    2014-01-01

    This paper presents several implementations of Syn- thetic Aperture Sequential Beamforming (SASB) on commer- cially available hand-held devices. The implementations include real-time wireless reception of ultrasound radio frequency sig- nals and GPU processing for B-mode imaging. The proposed...... implementation demonstrates that SASB can be executed in-time for real-time ultrasound imaging. The wireless communication between probe and processing device satisfies the required bandwidth for real-time data transfer with current 802.11ac technology. The implementation is evaluated using four different hand-held...

  1. Phase noise from aircraft motion: Compensation and effect on synthetic aperture radar images

    Science.gov (United States)

    Gabriel, Andrew K.; Goldstein, Richard M.

    1986-01-01

    Image degradation of airborne SAR imagery caused by phase errors introduced in the received signal by aircraft motion is discussed. Mechanical motion has a small bandwidth and does not affect the range signal, where the total echo time is typically 60 microsec. However, since the aperture length can be several seconds, the synthesized azimuth signal can have significant errors of which phase noise is the most important. An inertial navigation system can be used to compensate for these errors when processing the images. Calculations to evaluate how much improvement results from compensation are outlined.

  2. Functional Imaging of Broca’s Area in Native Persian Speakers: An fMRI Study

    Directory of Open Access Journals (Sweden)

    A Mahdavi

    2008-12-01

    Full Text Available Background/Objective: The problem of localization of speech associated cortices using noninvasive methods has been of utmost importance in many neuroimaging studies, but the results are difficult to resolve for specific neurosurgical applications. In this study, we used fMRI to delineate language-related brain activation patterns with emphasis on the Broca's area during the execution of two Persian language tasks."nPatients and Methods: The subjects comprised of nine healthy right-handed men who participated voluntarily in this study. They performed two consequent fMRI paradigms namely; "Word Production" and "Reverse Word Reading". The fMRI data were collected and analyzed. Then, functional images were registered to anatomical images using FSL software. The laterality indices were also calculated in regions of interest with different threshold levels."nResults: The results indicate that Broca's area, as the classical language-production center, was robustly activated while performing these two tasks. In eight out of nine subjects, the left hemisphere dominancy and Broca's area activation were observed and in one case activation was prominent in the homologous area in the right hemisphere."nConclusion: Similar pattern of cortical activation during Persian word production and Anglophone languages such as English was revealed. fMRI is a valuable means for brain mapping in language studies.

  3. Extended depth-of-field 3D endoscopy with synthetic aperture integral imaging using an electrically tunable focal-length liquid-crystal lens.

    Science.gov (United States)

    Wang, Yu-Jen; Shen, Xin; Lin, Yi-Hsin; Javidi, Bahram

    2015-08-01

    Conventional synthetic-aperture integral imaging uses a lens array to sense the three-dimensional (3D) object or scene that can then be reconstructed digitally or optically. However, integral imaging generally suffers from a fixed and limited range of depth of field (DOF). In this Letter, we experimentally demonstrate a 3D integral-imaging endoscopy with tunable DOF by using a single large-aperture focal-length-tunable liquid crystal (LC) lens. The proposed system can provide high spatial resolution and an extended DOF in synthetic-aperture integral imaging 3D endoscope. In our experiments, the image plane in the integral imaging pickup process can be tuned from 18 to 38 mm continuously using a large-aperture LC lens, and the total DOF is extended from 12 to 51 mm. To the best of our knowledge, this is the first report on synthetic aperture integral imaging 3D endoscopy with a large-aperture LC lens that can provide high spatial resolution 3D imaging with an extend DOF.

  4. Computer simulation of the effects of a distributed array antenna on synthetic aperture radar images

    Science.gov (United States)

    Estes, J. M.

    1985-01-01

    The ARL:UT orbital SAR simulation has been upgraded to use three-dimensional antenna gain patterns. This report describes the modifications and presents quantitative image analyses of a simulation using antenna patterns generated from the modeling of a distributed array antenna.

  5. Digital interpolators for polar format processing. [of synthetic aperture radar images

    Science.gov (United States)

    Adams, John W.; Hudson, Ralph E.; Bayma, Robert W.; Nelson, Jeffrey E.

    1989-01-01

    The polar format approach to SAR image formation requires data to be interpolated from a warped grid onto a Cartesian lattice. In general, this requires that data be interpolated between varying sampling rates. In this paper, frequency-domain optimality criteria for polar format interpolators are defined and justified, and an approach to designing the corresponding digital filters is described.

  6. 3D synthetic aperture imaging using a virtual source element in the elevation plane

    DEFF Research Database (Denmark)

    Nikolov, Svetoslav; Jensen, Jørgen Arendt

    2000-01-01

    dynamic focusing in the elevation plane. A 0.1 mm point scatterer was mounted in an agar block and scanned in a water bath. The transducer is a 64 elements linear array with a pitch of 209 μm. The transducer height is 4 mm in the elevation plane and it is focused at 20 mm giving a F-number of 5. The point....... However, the resolution in the elevation plane is determined by the fixed mechanical elevation focus. This paper suggests to post-focus the RF lines from several adjacent planes in the elevation direction using the elevation focal point of the transducer as a virtual source element, in order to obtain...... scatterer was positioned 96 mm from the transducer surface. The transducer was translated in the elevation direction from -13 to +13 mm over the scatterer at steps of 0.375 mm. Each of the 70 planes is scanned using synthetic transmit aperture with 8 emissions. The beam-formed RF lines from the planes...

  7. Efficient imaging approach for spaceborne sliding spotlight synthetic aperture radar with a small squint angle

    Science.gov (United States)

    Zhou, Peng; Chen, Yanmei; Sun, Weifeng; Wan, Yong; Dai, Yongshou

    2015-01-01

    Several existing algorithms for squinted sliding spotlight synthetic aperture radar (SAR) suffer from low efficiency, despite their good focusing abilities. Their low speeds are primarily due to the use of wave-number domain (Omega-K) processing after spectrum unfolding in the azimuth frequency domain. Omega-K processing is chosen in these algorithms due to its focusing ability at large squint angles. However, in most scenarios, spaceborne SARs operate with small squint angles that are generally not greater than 5 deg. In these scenarios, Omega-K processing is not necessary and is not preferred due to its computational burden. Thus, in this study, we extend a classic, two-step algorithm based on the chirp z-transformation for the efficient processing of SAR data acquired in spaceborne sliding spotlight mode at a small squint angle. The modified azimuth-filtering and focusing processing is used to compensate for the additional Doppler bandwidth caused by the antenna squinting and is described in detail. The simulation results show the good focusing ability of the proposed algorithm and validate the improvement in computational efficiency.

  8. Method for providing a polarization filter for processing synthetic aperture radar image data

    Science.gov (United States)

    Dubois, Pascale C. (Inventor); vanZyl, Jakob J. (Inventor)

    1991-01-01

    A polarization filter can maximize the signal-to-noise ratio of a polarimetric SAR and help discriminate between targets or enhance image features, e.g., enhance contract between different types of target. The method disclosed is based on the Stokes matrix/Stokes vector representation, so the targets of interest can be extended targets, and the method can also be applied to the case of bistatic polarimetric radars.

  9. FTIR imaging in diffusion studies: CO2 and H2O in a synthetic sector-zoned beryl

    Directory of Open Access Journals (Sweden)

    Giancarlo eDella Ventura

    2015-06-01

    Full Text Available In this work we investigate the strongly inhomogeneous distribution of CO2 and H2O in a synthetic beryl having a peculiar hourglass zoning of Cr due to the crystal growth. The sample was treated at 800°C, 500 MPa, in a CO2-rich atmosphere. High-resolution FESEM images revealed that the hourglass boundary is not correlated to physical discontinuities, at least at the scale of tens of nanometers. Polarized FPA-FTIR imaging, on the other side, revealed that the chemical zoning acts as a fast pathway for carbon dioxide diffusion, a feature never observed so far in minerals. The hourglass zone boundary may be thus considered as a structural defect possibly due to the mismatch induced by the different growth rates of each sector. High-resolution synchrotron-light FTIR imaging, in addition, also allows enhancement of CO2 diffusion along the hourglass boundary to be distinguished from diffusion along fractures in the grain. Therefore, FTIR imaging provides evidence that different diffusion mechanisms may locally combine, suggesting that the distribution of the target molecules needs to be be carefully characterized in experimental studies. This piece of information is mandatory when the study is aimed at extracting diffusion coefficients from analytical profiles. Combination of TOF-SIMS and FPA data shows a significant depletion of type II H2O along the hourglass boundary, indicating that water diffusion could be controlled by the distribution of alkali cations within channels, coupled to a plug effect of CO2.

  10. Large-scale numerical simulations of star formation put to the test: Comparing synthetic images and actual observations for statistical samples of protostars

    CERN Document Server

    Frimann, Søren; Haugbølle, Troels

    2015-01-01

    (abridged) Context: Both observations and simulations of embedded protostars have progressed rapidly in recent years. Bringing them together is an important step in advancing our knowledge about the earliest phases of star formation. Aims: To compare synthetic continuum images and SEDs, created from large-scale numerical simulations, to observational studies - thereby aiding both in the interpretation of observations and test the fidelity of the simulations. Methods: The radiative transfer code RADMC-3D is used to create synthetic continuum images and SEDs of protostellar systems in a large numerical simulation of a molecular cloud. More than 13000 unique radiative transfer models are produced of a variety of different protostellar systems. Results: Over the course of 0.76 Myr more than 500 protostars are formed in the simulation - primarily within two sub-clusters. Synthetic SEDs are used to calculate evolutionary tracers Tbol and Lsmm/Lbol. It is shown that, while the observed distributions of tracers are w...

  11. Monitoring cyanobacteria-dominant algal blooms in eutrophicated Taihu Lake in China with synthetic aperture radar images

    Science.gov (United States)

    Wang, Ganlin; Li, Junsheng; Zhang, Bing; Shen, Qian; Zhang, Fangfang

    2015-01-01

    Monitoring algal blooms by optical remote sensing is limited by cloud cover. In this study, synthetic aperture radar (SAR) was deployed with the aim of monitoring cyanobacteria-dominant algal blooms in Taihu Lake in cloudy weather. The study shows that dark regions in the SAR images caused by cyanobacterial blooms damped the microwave backscatter of the lake surface and were consistent with the regions of algal blooms in quasi-synchronous optical images, confirming the applicability of SAR for detection of surface blooms. Low backscatter may also be associated with other factors such as low wind speeds, resulting in interference when monitoring algal blooms using SAR data alone. After feature extraction and selection, the dark regions were classified by the support vector machine method with an overall accuracy of 67.74%. SAR can provide a reference point for monitoring cyanobacterial blooms in the lake, particularly when weather is not suitable for optical remote sensing. Multi-polarization and multi-band SAR can be considered for use in the future to obtain more accurate information regarding algal blooms from SAR data.

  12. Forest height estimation from mountain forest areas using general model-based decomposition for polarimetric interferometric synthetic aperture radar images

    Science.gov (United States)

    Minh, Nghia Pham; Zou, Bin; Cai, Hongjun; Wang, Chengyi

    2014-01-01

    The estimation of forest parameters over mountain forest areas using polarimetric interferometric synthetic aperture radar (PolInSAR) images is one of the greatest interests in remote sensing applications. For mountain forest areas, scattering mechanisms are strongly affected by the ground topography variations. Most of the previous studies in modeling microwave backscattering signatures of forest area have been carried out over relatively flat areas. Therefore, a new algorithm for the forest height estimation from mountain forest areas using the general model-based decomposition (GMBD) for PolInSAR image is proposed. This algorithm enables the retrieval of not only the forest parameters, but also the magnitude associated with each mechanism. In addition, general double- and single-bounce scattering models are proposed to fit for the cross-polarization and off-diagonal term by separating their independent orientation angle, which remains unachieved in the previous model-based decompositions. The efficiency of the proposed approach is demonstrated with simulated data from PolSARProSim software and ALOS-PALSAR spaceborne PolInSAR datasets over the Kalimantan areas, Indonesia. Experimental results indicate that forest height could be effectively estimated by GMBD.

  13. Quantitative sodium MR imaging of native versus transplanted kidneys using a dual-tuned proton/sodium ({sup 1}H/{sup 23}Na) coil: initial experience

    Energy Technology Data Exchange (ETDEWEB)

    Moon, Chan Hong; Furlan, Alessandro [University of Pittsburgh, Department of Radiology, Pittsburgh, PA (United States); Kim, Jung-Hwan; Bae, Kyongtae Ty [University of Pittsburgh, Department of Radiology, Pittsburgh, PA (United States); University of Pittsburgh, Department of Bioengineering, Pittsburgh, PA (United States); Zhao, Tiejun [MR R and D Collaborations, Siemens Medical Solutions USA, Inc, Pittsburgh, PA (United States); Shapiro, Ron [Thomas E. Starzl Transplantation Institute, Department of Surgery, Pittsburgh, PA (United States)

    2014-06-15

    To compare sodium ({sup 23}Na) characteristics between native and transplanted kidneys using dual-tuned proton ({sup 1}H)/sodium MRI. Six healthy volunteers and six renal transplant patients (3 normal function, 3 acute allograft rejection) were included. Proton/sodium MRI was obtained at 3 T using a dual-tuned coil. Signal to noise ratio (SNR), sodium concentration ([{sup 23}Na]) and cortico-medullary sodium gradient (CMSG) were measured. Reproducibility of [{sup 23}Na] measurement was also tested. SNR, [{sup 23}Na] and CMSG of the native and transplanted kidneys were compared. Proton and sodium images of kidneys were successfully acquired. SNR and [{sup 23}Na] measurements of the native kidneys were reproducible at two different sessions. [{sup 23}Na] and CMSG of the transplanted kidneys was significantly lower than those of the native kidneys: 153.5 ± 11.9 vs. 192.9 ± 9.6 mM (P = 0.002) and 8.9 ± 1.5 vs. 10.5 ± 0.9 mM/mm (P = 0.041), respectively. [{sup 23}Na] and CMSG of the transplanted kidneys with normal function vs. acute rejection were not statistically different. Sodium quantification of kidneys was reliably performed using proton/sodium MRI. [{sup 23}Na] and CMSG of the transplanted kidneys were lower than those of the native kidneys, but without a statistically significant difference between patients with or without renal allograft rejection. (orig.)

  14. Extending the Life of Virtual Heritage: Reuse of Tls Point Clouds in Synthetic Stereoscopic Spherical Images

    Science.gov (United States)

    Garcia Fernandez, J.; Tammi, K.; Joutsiniemi, A.

    2017-02-01

    Recent advances in Terrestrial Laser Scanner (TLS), in terms of cost and flexibility, have consolidated this technology as an essential tool for the documentation and digitalization of Cultural Heritage. However, once the TLS data is used, it basically remains stored and left to waste.How can highly accurate and dense point clouds (of the built heritage) be processed for its reuse, especially to engage a broader audience? This paper aims to answer this question by a channel that minimizes the need for expert knowledge, while enhancing the interactivity with the as-built digital data: Virtual Heritage Dissemination through the production of VR content. Driven by the ProDigiOUs project's guidelines on data dissemination (EU funded), this paper advances in a production path to transform the point cloud into virtual stereoscopic spherical images, taking into account the different visual features that produce depth perception, and especially those prompting visual fatigue while experiencing the VR content. Finally, we present the results of the Hiedanranta's scans transformed into stereoscopic spherical animations.

  15. Millimeter-wave passive ultra-compact imaging technology for synthetic vision & mobile platforms

    Science.gov (United States)

    Olsen, Randall

    1996-01-01

    Substantial technical progress was made on all of the three high-risk subsystems of this program. The subsystems include dielectric antenna, G-band receiver, and electro-optic image processor. Progress is approximately on-schedule for both the receiver and the electro-optic processor development, while greater than anticipated challenges have been discovered in the dielectric antenna development. Much of the information in this report was covered in greater detail in the One-Year Review Meeting held at TTC on 22 February 1996. The performance goals of the dielectric antenna project are: Scan Angle -- 20 deg. desired; Loss -- 6 dB end to end (3 dB average); Frequency -- 206-218 GHz (6% bandwidth); Beam width -- 0.25 deg.; and Length -- 12 inches. The scan angle requirement was chosen to satisfy the needs of aircraft pilots. This requirement, coupled with the presently limited bandwidth processors (1 GHz state-of-the-art and 12 GHz in development in this program) forces the antenna to be dielectric (high scan angle air-filled waveguide-based antennas would be too lossy and their performance would vary too much as a function of frequency). A high dielectric constant (e.g., 10) was initially chosen for the dielectric material. This choice lead to the following fabrication challenges: total thickness variation (TTV) tolerance is 1 micrometer; coupler spacing tolerance is 1 micrometer; width tolerance is larger, but unknown, and the surfaces must have mirror finish. Also of importance is the difficulty in obtaining raw materials that satisfy the overall length requirement of 12 inches while simultaneously satisfying the above specifications.

  16. Polarimetric analysis of radar backscatter from ground-based scatterometers and wheat biomass monitoring with advanced synthetic aperture radar images

    Science.gov (United States)

    He, Lei; Tong, Ling; Li, Yuxia; Chen, Yan; Tan, Longfei; Guo, Caizheng

    2016-04-01

    This article presents an analysis of the scattering measurements for an entire wheat growth cycle by ground-based scatterometers at a frequency of 5.3 GHz. Since wheat ears are related to wheat growth and yield, the radar backscatter of wheat was analyzed at two different periods, i.e., with and without wheat ears. Simultaneously, parameters such as wheat and soil characteristics as well as volume scattering and soil scattering were analyzed for the two periods during the entire growth cycle. Wheat ears have been demonstrated to have a great influence on radar backscatter; therefore, a modified version of water-cloud model used for retrieving biomass should consider the effect of wheat ears. This work presents two retrieval models based on the water-cloud model and adopts the advanced integral equation model to simulate the soil backscatter before the heading stage and the backscatter from the layer under wheat ears after the heading stage. The research results showed that the biomass retrieved from the advanced synthetic aperture radar (ASAR) images to agree well with the data measured in situ after setting the modified water-cloud model for the growth stages with ears. Furthermore, it was concluded that wheat ears should form an essential component of theoretical modeling as they influence the final yield.

  17. MR-OPERA: A Multicenter/Multivendor Validation of Magnetic Resonance Imaging-Only Prostate Treatment Planning Using Synthetic Computed Tomography Images.

    Science.gov (United States)

    Persson, Emilia; Gustafsson, Christian; Nordström, Fredrik; Sohlin, Maja; Gunnlaugsson, Adalsteinn; Petruson, Karin; Rintelä, Niina; Hed, Kristoffer; Blomqvist, Lennart; Zackrisson, Björn; Nyholm, Tufve; Olsson, Lars E; Siversson, Carl; Jonsson, Joakim

    2017-06-16

    To validate the dosimetric accuracy and clinical robustness of a commercially available software for magnetic resonance (MR) to synthetic computed tomography (sCT) conversion, in an MR imaging-only workflow for 170 prostate cancer patients. The 4 participating centers had MriPlanner (Spectronic Medical), an atlas-based sCT generation software, installed as a cloud-based service. A T2-weighted MR sequence, covering the body contour, was added to the clinical protocol. The MR images were sent from the MR scanner workstation to the MriPlanner platform. The sCT was automatically returned to the treatment planning system. Four MR scanners and 2 magnetic field strengths were included in the study. For each patient, a CT-treatment plan was created and approved according to clinical practice. The sCT was rigidly registered to the CT, and the clinical treatment plan was recalculated on the sCT. The dose distributions from the CT plan and the sCT plan were compared according to a set of dose-volume histogram parameters and gamma evaluation. Treatment techniques included volumetric modulated arc therapy, intensity modulated radiation therapy, and conventional treatment using 2 treatment planning systems and different dose calculation algorithms. The overall (multicenter/multivendor) mean dose differences between sCT and CT dose distributions were below 0.3% for all evaluated organs and targets. Gamma evaluation showed a mean pass rate of 99.12% (0.63%, 1 SD) in the complete body volume and 99.97% (0.13%, 1 SD) in the planning target volume using a 2%/2-mm global gamma criteria. Results of the study show that the sCT conversion method can be used clinically, with minimal differences between sCT and CT dose distributions for target and relevant organs at risk. The small differences seen are consistent between centers, indicating that an MR imaging-only workflow using MriPlanner is robust for a variety of field strengths, vendors, and treatment techniques. Copyright © 2017 The

  18. Coastal Monitoring Using L-band Synthetic Aperture Radar (SAR) Image Data - Some Case Studies in Asian Delta Areas

    Science.gov (United States)

    Tanaka, A.

    2014-12-01

    Coastal geomorphology is highly variable as it is affected by sea-level changes and other naturally- and human-induced fluctuations. To effectively assess and monitor geomorphological changes in various time scales is thus critical for coastal management. Asian mega deltas are vulnerable to a sea-level rise due to its low-lying delta plain, and are dynamic region given a large amount of sediment supply. However, limited data availability and accessibility in the deltas have prevented establishment of systematic coastal monitoring. A variety of remote sensing systems can be used to monitor geomorphological changes in coastal areas as it has wide spatial coverage and high temporal repeatability. Especially, analysis using SAR (Synthetic Aperture Radar) data not affected by the cloud conditions offer potential for monitoring in the monsoon Asia region. We will present some case studies of Asian coastal regions using L-band SAR data, ALOS (Advanced Land Observing Satellite) PALSAR (Phased Array type L-band SAR) and JERS-1 (Japanese Earth Resource Satellite-1) SAR data. One example is that time-series of radar amplitude images can be used to delineate changes quantitatively of the areal extent of river-mouth bars in distributaries of the Mekong River delta. It shows that the estimated areas of river mouthbars gradually increase on an annual time scale, and seasonal variations of areas were also recognized. Another example is that differential SAR interferometry is applied to the coast of the Yellow River delta in China. It shows very high subsidence rates, likely due to groundwater pumping. A further example is that we apply a SAR interferometry time series analysis to monitor ground deformations in the lower Chao Phraya delta plain, Thailand. A single reference time series interferogram from the stacking of unwrapped phases were applied. The subsidence and uplift pattern observed using the SAR interferometry time series analysis highlights the spatial complexity

  19. Cartilage quality in rheumatoid arthritis: comparison of T2* mapping, native T1 mapping, dGEMRIC, {delta}R1 and value of pre-contrast imaging

    Energy Technology Data Exchange (ETDEWEB)

    Buchbender, Christian; Scherer, Axel; Kroepil, Patric; Quentin, Michael; Reichelt, Dorothea C.; Lanzman, Rotem S.; Mathys, Christian; Blondin, Dirk; Wittsack, Hans-Joerg; Antoch, Gerald; Miese, Falk [University Duesseldorf, Department of Diagnostic and Interventional Radiology, Medical Faculty, Duesseldorf (Germany); Koerbl, Birthe [Heinrich-Heine-University, Department of Endocrinology, Diabetology and Rheumatology, Medical Faculty, Duesseldorf (Germany); Heinrich-Heine-University, Leibniz Centre for Diabetes Research, Institute of Biometrics and Epidemiology, German Diabetes Centre, Duesseldorf (Germany); Bittersohl, Bernd; Zilkens, Christoph [Heinrich-Heine-University, Department of Orthopaedics, Medical Faculty, Duesseldorf (Germany); Hofer, Matthias [Heinrich-Heine-University, Medical Education Group, Medical School, Duesseldorf (Germany); Schneider, Matthias; Ostendorf, Benedikt [Heinrich-Heine-University, Department of Endocrinology, Diabetology and Rheumatology, Medical Faculty, Duesseldorf (Germany)

    2012-06-15

    To prospectively evaluate four non-invasive markers of cartilage quality - T2* mapping, native T1 mapping, dGEMRIC and {delta}R1 - in healthy volunteers and rheumatoid arthritis (RA) patients. Cartilage of metacarpophalangeal (MCP) joints II were imaged in 28 consecutive subjects: 12 healthy volunteers [9 women, mean (SD) age 52.67 (9.75) years, range 30-66] and 16 RA patients with MCP II involvement [12 women, mean (SD) age 58.06 (12.88) years, range 35-76]. Sagittal T2* mapping was performed with a multi-echo gradient-echo on a 3 T MRI scanner. For T1 mapping the dual flip angle method was applied prior to native T1 mapping and 40 min after gadolinium application (delayed gadolinium-enhanced MRI of cartilage, dGEMRIC, T1{sub Gd}). The difference in the longitudinal relaxation rate induced by gadolinium ({delta}R1) was calculated. The area under the receiver operating characteristic curve (AROC) was used to test for differentiation of RA patients from healthy volunteers. dGEMRIC (AUC 0.81) and {delta}R1 (AUC 0.75) significantly differentiated RA patients from controls. T2* mapping (AUC 0.66) and native T1 mapping (AUC 0.66) were not significantly different in RA patients compared to controls. The data support the use of dGEMRIC for the assessment of MCP joint cartilage quality in RA. T2* and native T1 mapping are of low diagnostic value. Pre-contrast T1 mapping for the calculation of {delta}R1 does not increase the diagnostic value of dGEMRIC. (orig.)

  20. Part task investigation of multispectral image fusion using gray scale and synthetic color night-vision sensor imagery for helicopter pilotage

    Science.gov (United States)

    Steele, Paul M.; Perconti, Philip

    1997-06-01

    Today, night vision sensor and display systems used in the pilotage or navigation of military helicopters are either long wave IR thermal sensors (8 - 12 microns) or image intensified, visible and near IR (0.6 - 0.9 microns), sensors. The sensor imagery is displayed using a monochrome phosphor on a Cathode Ray Tube or night vision goggle. Currently, there is no fielded capability to combine the best attributes of the emissive radiation sensed by the thermal sensor and the reflected radiation sensed by the image intensified sensor into a single fused image. However, recent advances in signal processing have permitted the real time image fusion and display of multispectral sensors in either monochrome or synthetic chromatic form. The merits of such signal processing is explored. A part task simulation using a desktop computer, video playback unit, and a biocular head mounted display was conducted. Response time and accuracy measures of test subject responses to visual perception tasks were taken. Subjective ratings were collected to determine levels of pilot acceptance. In general, fusion based formats resulted in better subject performance. The benefits of integrating synthetic color to fused imagery, however, is dependent on the color algorithm used, the visual task performed, and scene content.

  1. Comparison of spoiled gradient echo and steady-state free-precession imaging for native myocardial T1 mapping using the slice-interleaved T1 mapping (STONE) sequence.

    Science.gov (United States)

    Jang, Jihye; Bellm, Steven; Roujol, Sébastien; Basha, Tamer A; Nezafat, Maryam; Kato, Shingo; Weingärtner, Sebastian; Nezafat, Reza

    2016-10-01

    Cardiac T1 mapping allows non-invasive imaging of interstitial diffuse fibrosis. Myocardial T1 is commonly calculated by voxel-wise fitting of the images acquired using balanced steady-state free precession (SSFP) after an inversion pulse. However, SSFP imaging is sensitive to B1 and B0 imperfection, which may result in additional artifacts. A gradient echo (GRE) imaging sequence has been used for myocardial T1 mapping; however, its use has been limited to higher magnetic field to compensate for the lower signal-to-noise ratio (SNR) of GRE versus SSFP imaging. A slice-interleaved T1 mapping (STONE) sequence with SSFP readout (STONE-SSFP) has been recently proposed for native myocardial T1 mapping, which allows longer recovery of magnetization (>8 R-R) after each inversion pulse. In this study, we hypothesize that a longer recovery allows higher SNR and enables native myocardial T1 mapping using STONE with GRE imaging readout (STONE-GRE) at 1.5T. Numerical simulations and phantom and in vivo imaging were performed to compare the performance of STONE-GRE and STONE-SSFP for native myocardial T1 mapping at 1.5T. In numerical simulations, STONE-SSFP shows sensitivity to both T2 and off resonance. Despite the insensitivity of GRE imaging to T2 , STONE-GRE remains sensitive to T2 due to the dependence of the inversion pulse performance on T2 . In the phantom study, STONE-GRE had inferior accuracy and precision and similar repeatability as compared with STONE-SSFP. In in vivo studies, STONE-GRE and STONE-SSFP had similar myocardial native T1 times, precisions, repeatabilities and subjective T1 map qualities. Despite the lower SNR of the GRE imaging readout compared with SSFP, STONE-GRE provides similar native myocardial T1 measurements, precision, repeatability, and subjective image quality when compared with STONE-SSFP at 1.5T.

  2. Solid-phase synthetic strategy and bioevaluation of a labeled delta-opioid receptor ligand Dmt-Tic-Lys for in vivo imaging.

    Science.gov (United States)

    Josan, Jatinder S; Morse, David L; Xu, Liping; Trissal, Maria; Baggett, Brenda; Davis, Peg; Vagner, Josef; Gillies, Robert J; Hruby, Victor J

    2009-06-18

    A general solid-phase synthetic strategy is developed to prepare fluorescent and/or lanthanide-labeled derivatives of the delta-opioid receptor (deltaOR) ligand H-Dmt-Tic-Lys(R)-OH. The high delta-OR affinity (K(i) = 3 nM) and desirable in vivo characteristics of the Cy5 derivative 1 suggest its usefulness for structure-function studies and receptor localization and as a high-contrast noninvasive molecular marker for live imaging ex vivo or in vivo.

  3. Three-dimensional interferometric inverse synthetic aperture radar imaging of maneuvering target based on the joint cross modified Wigner-Ville distribution

    Science.gov (United States)

    Lv, Qian; Su, Tao; Zheng, Jibin; Zhang, Jiancheng

    2016-01-01

    Inverse synthetic aperture radar (ISAR) can achieve high-resolution two-dimensional images of maneuvering targets. However, due to the indeterminate relative motion between radar and target, ISAR imaging does not provide the three-dimensional (3-D) position information of a target and suffers from great difficulty in target recognition. To tackle this issue, a 3-D interferometric ISAR (InISAR) imaging algorithm based on the joint cross modified Wigner-Ville distribution (MWVD) is presented to form 3-D images of maneuvering targets. First, we form two orthogonal interferometric baselines with three receiving antennas to establish an InISAR imaging system. Second, after the uniform range alignment and phase adjustment, the joint cross MWVD is used for all range cell of each antenna pair to generate the separation of the scatterer as well as preserve the phase that contains position information of the scatterer. At last, the 3-D images of the target can be directly reconstructed from the distribution. Simulation results demonstrate the validity of the proposal.

  4. Science Results from the Spaceborne Imaging Radar-C/X-Band Synthetic Aperture Radar (SIR-C/X-SAR): Progress Report

    Science.gov (United States)

    Evans, Diane L. (Editor); Plaut, Jeffrey (Editor)

    1996-01-01

    The Spaceborne Imaging Radar-C/X-band Synthetic Aperture Radar (SIR-C/X-SAR) is the most advanced imaging radar system to fly in Earth orbit. Carried in the cargo bay of the Space Shuttle Endeavour in April and October of 1994, SIR-C/X-SAR simultaneously recorded SAR data at three wavelengths (L-, C-, and X-bands; 23.5, 5.8, and 3.1 cm, respectively). The SIR-C/X-SAR Science Team consists of 53 investigator teams from more than a dozen countries. Science investigations were undertaken in the fields of ecology, hydrology, ecology, and oceanography. This report contains 44 investigator team reports and several additional reports from coinvestigators and other researchers.

  5. Fast image-formation algorithm for ultrahigh-resolution airborne squint spotlight synthetic aperture radar based on adaptive sliding receive-window technique

    Science.gov (United States)

    Yang, Wei; Zeng, Hong-cheng; Chen, Jie; Wang, Peng-bo

    2014-01-01

    Adaptive sliding receive-window (ASRW) technique was usually introduced in airborne squint synthetic aperture radar (SAR) systems. Airborne squint spotlight SAR varies its receive-window starting time pulse-by-pulse as a function of range-walk, namely, the linear term of range cell migration (RCM). As a result, a huge data volume of the highly squint spotlight SAR echo signal can be significantly reduced. Because the ASRW technique changes the echo-receive starting time and Doppler history, the conventional image algorithm cannot be employed to directly focus airborne squint spotlight ASRW-SAR data. Therefore, a fast image-formation algorithm, based on the principle of the wave number domain algorithm (WDA) and azimuth deramping processing, was proposed for accurately and efficiently focusing the squint spotlight ASRW-SAR data. Azimuth deramping preprocessing was implemented for eliminating azimuth spectrum aliasing. Moreover, bulk compression and modified Stolt mapping were utilized for high-precision focusing. Additionally, geometric correction was employed for compensating the image distortion resulting from the ASRW technique. The proposed algorithm was verified by evaluating the image performance of point targets in different squint angles. In addition, a detailed analysis of computation loads in the appendix indicates that the processing efficiency can be greatly improved, e.g., the processing efficiency could be improved by 17 times in the 70-deg squint angle by applying the proposed image algorithm to the squint spotlight ASRW-SAR data.

  6. Synthetic biology and metabolic engineering.

    Science.gov (United States)

    Stephanopoulos, Gregory

    2012-11-16

    Metabolic engineering emerged 20 years ago as the discipline occupied with the directed modification of metabolic pathways for the microbial synthesis of various products. As such, it deals with the engineering (design, construction, and optimization) of native as well as non-natural routes of product synthesis, aided in this task by the availability of synthetic DNA, the core enabling technology of synthetic biology. The two fields, however, only partially overlap in their interest in pathway engineering. While fabrication of biobricks, synthetic cells, genetic circuits, and nonlinear cell dynamics, along with pathway engineering, have occupied researchers in the field of synthetic biology, the sum total of these areas does not constitute a coherent definition of synthetic biology with a distinct intellectual foundation and well-defined areas of application. This paper reviews the origins of the two fields and advances two distinct paradigms for each of them: that of unit operations for metabolic engineering and electronic circuits for synthetic biology. In this context, metabolic engineering is about engineering cell factories for the biological manufacturing of chemical and pharmaceutical products, whereas the main focus of synthetic biology is fundamental biological research facilitated by the use of synthetic DNA and genetic circuits.

  7. Synthetic Aperture Radar Interferometry

    Science.gov (United States)

    Rosen, P. A.; Hensley, S.; Joughin, I. R.; Li, F.; Madsen, S. N.; Rodriguez, E.; Goldstein, R. M.

    1998-01-01

    Synthetic aperture radar interferometry is an imaging technique for measuring the topography of a surface, its changes over time, and other changes in the detailed characteristics of the surface. This paper reviews the techniques of interferometry, systems and limitations, and applications in a rapidly growing area of science and engineering.

  8. Time-Resolved Spectroscopy and Near Infrared Imaging for Prostate Cancer Detection: Receptor-targeted and Native Biomarker

    Science.gov (United States)

    Pu, Yang

    Optical spectroscopy and imaging using near-infrared (NIR) light provides powerful tools for non-invasive detection of cancer in tissue. Optical techniques are capable of quantitative reconstructions maps of tissue absorption and scattering properties, thus can map in vivo the differences in the content of certain marker chromophores and/or fluorophores in normal and cancerous tissues (for example: water, tryptophan, collagen and NADH contents). Potential clinical applications of optical spectroscopy and imaging include functional tumor detection and photothermal therapeutics. Optical spectroscopy and imaging apply contrasts from intrinsic tissue chromophores such as water, collagen and NADH, and extrinsic optical contrast agents such as Indocyanine Green (ICG) to distinguish disease tissue from the normal one. Fluorescence spectroscopy and imaging also gives high sensitivity and specificity for biomedical diagnosis. Recent developments on specific-targeting fluorophores such as small receptor-targeted dye-peptide conjugate contrast agent offer high contrast between normal and cancerous tissues hence provide promising future for early tumour detection. This thesis focus on a study to distinguish the cancerous prostate tissue from the normal prostate tissues with enhancement of specific receptor-targeted prostate cancer contrast agents using optical spectroscopy and imaging techniques. The scattering and absorption coefficients, and anisotropy factor of cancerous and normal prostate tissues were investigated first as the basis for the biomedical diagnostic and optical imaging. Understanding the receptors over-expressed prostate cancer cells and molecular target mechanism of ligand, two small ICG-derivative dye-peptides, namely Cypate-Bombesin Peptide Analogue Conjugate (Cybesin) and Cypate-Octreotate Peptide Conjugate (Cytate), were applied to study their clinical potential for human prostate cancer detection. In this work, the steady-state and time

  9. Differential Effects of Structural Modifications on the Competition of Chalcones for the PIB Amyloid Imaging Ligand-Binding Site in Alzheimer's Disease Brain and Synthetic Aβ Fibrils.

    Science.gov (United States)

    Fosso, Marina Y; McCarty, Katie; Head, Elizabeth; Garneau-Tsodikova, Sylvie; LeVine, Harry

    2016-02-17

    Alzheimer's disease (AD) is a complex brain disorder that still remains ill defined. In order to understand the significance of binding of different clinical in vivo imaging ligands to the polymorphic pathological features of AD brain, the molecular characteristics of the ligand interacting with its specific binding site need to be defined. Herein, we observed that tritiated Pittsburgh Compound B ((3)H-PIB) can be displaced from synthetic Aβ(1-40) and Aβ(1-42) fibrils and from the PIB binding complex purified from human AD brain (ADPBC) by molecules containing a chalcone structural scaffold. We evaluated how substitution on the chalcone scaffold alters its ability to displace (3)H-PIB from the synthetic fibrils and ADPBC. By comparing unsubstituted core chalcone scaffolds along with the effects of bromine and methyl substitution at various positions, we found that attaching a hydroxyl group on the ring adjacent to the carbonyl group (ring I) of the parent member of the chalcone family generally improved the binding affinity of chalcones toward ADPBC and synthetic fibrils F40 and F42. Furthermore, any substitution on ring I at the ortho-position of the carbonyl group greatly decreases the binding affinity of the chalcones, potentially as a result of steric hindrance. Together with the finding that neither our chalcones nor PIB interact with the Congo Red/X-34 binding site, these molecules provide new tools to selectively probe the PIB binding site that is found in human AD brain, but not in brains of AD pathology animal models. Our chalcone derivatives also provide important information on the effects of fibril polymorphism on ligand binding.

  10. Protein ligand-tethered synthetic calcium indicator for localization control and spatiotemporal calcium imaging in plant cells.

    Science.gov (United States)

    Takaoka, Yousuke; Shigenaga, Miyuki; Imai, Masaki; Nukadzuka, Yuuki; Ishimaru, Yasuhiro; Saito, Kei; Yokoyama, Ryusuke; Nishitani, Kazuhiko; Ueda, Minoru

    2016-01-01

    In plant biology, calcium ions are involved in a variety of intriguing biological phenomena as a secondary messenger. However, most conventional calcium indicators are not applicable for plant cells because of the difficulty with their localization control in plant cells. We here introduce a method to monitor spatiotemporal Ca(2+) dynamics in living plant cells based on linking the synthetic calcium indicator Calcium Green-1 to a natural product-based protein ligand. In a proof-of-concept study using cultured BY-2 cells overexpressing the target protein for the ligand, the ligand-tethered probe accumulated in the cytosol and nucleus, and enabled real-time monitoring of the cytosolic and nucleus Ca(2+) dynamics under the physiological condition. The present strategy using ligand-tethered fluorescent sensors may be successfully applied to reveal the spatiotemporal dynamics of calcium ions in living plant cells.

  11. Linear Dispersion Relation and Depth Sensitivity to Swell Parameters: Application to Synthetic Aperture Radar Imaging and Bathymetry

    Directory of Open Access Journals (Sweden)

    Valentina Boccia

    2015-01-01

    Full Text Available Long gravity waves or swell dominating the sea surface is known to be very useful to estimate seabed morphology in coastal areas. The paper reviews the main phenomena related to swell waves propagation that allow seabed morphology to be sensed. The linear dispersion is analysed and an error budget model is developed to assess the achievable depth accuracy when Synthetic Aperture Radar (SAR data are used. The relevant issues and potentials of swell-based bathymetry by SAR are identified and discussed. This technique is of particular interest for characteristic regions of the Mediterranean Sea, such as in gulfs and relatively close areas, where traditional SAR-based bathymetric techniques, relying on strong tidal currents, are of limited practical utility.

  12. Linear dispersion relation and depth sensitivity to swell parameters: application to synthetic aperture radar imaging and bathymetry.

    Science.gov (United States)

    Boccia, Valentina; Renga, Alfredo; Rufino, Giancarlo; D'Errico, Marco; Moccia, Antonio; Aragno, Cesare; Zoffoli, Simona

    2015-01-01

    Long gravity waves or swell dominating the sea surface is known to be very useful to estimate seabed morphology in coastal areas. The paper reviews the main phenomena related to swell waves propagation that allow seabed morphology to be sensed. The linear dispersion is analysed and an error budget model is developed to assess the achievable depth accuracy when Synthetic Aperture Radar (SAR) data are used. The relevant issues and potentials of swell-based bathymetry by SAR are identified and discussed. This technique is of particular interest for characteristic regions of the Mediterranean Sea, such as in gulfs and relatively close areas, where traditional SAR-based bathymetric techniques, relying on strong tidal currents, are of limited practical utility.

  13. Vibrational spectroscopy and microscopic imaging: novel approaches for comparing barrier physical properties in native and human skin equivalents

    Science.gov (United States)

    Yu, Guo; Zhang, Guojin; Flach, Carol R.; Mendelsohn, Richard

    2013-06-01

    Vibrational spectroscopy and imaging have been used to compare barrier properties in human skin, porcine skin, and two human skin equivalents, Epiderm 200X with an enhanced barrier and Epiderm 200 with a normal barrier. Three structural characterizations were performed. First, chain packing and conformational order were compared in isolated human stratum corneum (SC), isolated porcine SC, and in the Epiderm 200X surface layers. The infrared (IR) spectrum of isolated human SC revealed a large proportion of orthorhombically packed lipid chains at physiological temperatures along with a thermotropic phase transition to a state with hexagonally packed chains. In contrast, the lipid phase at physiological temperatures in both porcine SC and in Epiderm 200X, although dominated by conformationally ordered chains, lacked significant levels of orthorhombic subcell packing. Second, confocal Raman imaging of cholesterol bands showed extensive formation of cholesterol-enriched pockets within the human skin equivalents (HSEs). Finally, IR imaging tracked lipid barrier dimensions as well as the spatial disposition of ordered lipids in human SC and Epiderm 200X. These approaches provide a useful set of experiments for exploring structural differences between excised human skin and HSEs, which in turn may provide a rationale for the functional differences observed among these preparations.

  14. Retrieval of the ocean wave spectrum in open and thin ice covered ocean waters from ERS Synthetic Aperture Radar images

    Energy Technology Data Exchange (ETDEWEB)

    De Carolis, G. [Consiglio Nazionale delle Ricerche, Istituto di Tecnologia Informatica Spaziale, Centro di Geodesia Spaziale G. Colombo, Terlecchia, MT (Italy)

    2001-02-01

    This paper concerns with the task of retrieving ocean wave spectra form imagery provided by space-borne SAR systems such as that on board ERS satellite. SAR imagery of surface wave fields travelling into open ocean and into thin sea ice covers composed of frazil and pancake icefields is considered. The major purpose is to gain insight on how the spectral changes can be related to sea ice properties of geophysical interest such as the thickness. Starting from SAR image cross spectra computed from Single Look Complex (SLC) SAR images, the ocean wave spectrum is retrieved using an inversion procedure based on the gradient descent algorithm. The capability of this method when applied to satellite SAR sensors is investigated. Interest in the SAR image cross spectrum exploitation is twofold: first, the directional properties of the ocean wave spectra are retained; second, external wave information needed to initialize the inversion procedure may be greatly reduced using only information included in the SAR image cross spectrum itself. The main drawback is that the wind waves spectrum could be partly lost and its spectral peak wave number underestimated. An ERS-SAR SLC image acquired on April 10, 1993 over the Greenland Sea was selected as test image. A pair of windows that include open-sea only and sea ice cover, respectively, were selected. The inversions were carried out using different guess wave spectra taken from SAR image cross spectra. Moreover, care was taken to properly handle negative values eventually occurring during the inversion runs. This results in a modification of the gradient descending the technique that is required if a non-negative solution of the wave spectrum is searched for. Results are discussed in view of the possibility of SAR data to detect ocean wave dispersion as a means for the retrieval of ice thickness.

  15. Synthetic foldamers.

    Science.gov (United States)

    Guichard, Gilles; Huc, Ivan

    2011-06-07

    Foldamers are artificial folded molecular architectures inspired by the structures and functions of biopolymers. This highlight focuses on important developments concerning foldamers produced by chemical synthesis and on the perspectives that these new self-organized molecular scaffolds offer. Progress in the field has led to synthetic objects that resemble small proteins in terms of size and complexity yet that may not contain any α-amino acids. Foldamers have introduced new tools and concepts to develop biologically active substances, synthetic receptors and novel materials.

  16. Inspection of copper canisters for spent nuclear fuel by means of ultrasound. Synthetic aperture imaging, evaluation of ultrasonic attenuation in copper

    Energy Technology Data Exchange (ETDEWEB)

    Stepinski, Tadeusz (ed.); Lingvall, Fredrik; Wennerstroem, Erik; Ping Wu [Uppsala Univ. (Sweden). Department of Engineering Sciences

    2006-01-15

    This report contains the research results concerning advanced ultrasound for the inspection of copper canisters for spent nuclear fuel obtained at Signals and Systems, Uppsala University in years 2004/2005. After a short introduction a new super-resolution synthetic aperture imaging (SRSAI) technique is proposed. The proposed SRSAI is characterized by an excellent lateral resolution and much higher signal to noise ratio compared with ESAFT which was proposed in our previous reports. The ESAFT is based on the assumption that probability density of the imaged targets (so called prior) is Gaussian, which is the simplest case for the analysis. The increased performance of SRSAI is due to more realistic assumption concerning probability density function of targets in the region of interest. It is shown, both using simulations and in an experiment that if the target reflectivity is assumed to be positive a substantial increase of resolution and signal to noise ratio in the reconstructed image can be obtained. In the second chapter the result of the evaluation of ultrasonic attenuation in copper blocks with different grain size is presented. A short presentation of basic theory of the buffer-rod and the immersion methods is given in the beginning (the detailed derivation is provided in the appendix). Then the measurement setup and copper specimens are specified and the results of measurements made on copper specimens are presented. Correlation between the attenuation and grain size for the inspected specimens is discussed.

  17. Synthetic Astrobiology

    Science.gov (United States)

    Rothschild, Lynn J.

    2016-01-01

    Synthetic biology - the design and construction of new biological parts and systems and the redesign of existing ones for useful purposes - has the potential to transform fields from pharmaceuticals to fuels. Our lab has focused on the potential of synthetic biology to revolutionize all three major parts of astrobiology: Where do we come from? Where are we going? and Are we alone? For the first and third, synthetic biology is allowing us to answer whether the evolutionary narrative that has played out on planet earth is likely to have been unique or universal. For example, in our lab we are re-evolving the biosynthetic pathways of amino acids in order to understand potential capabilities of an early organism with a limited repertoire of amino acids and developing techniques for the recovery of metals from spent electronics on other planetary bodies. And what about the limits for life? Can we create organisms that expand the envelope for life? In the future synthetic biology will play an increasing role in human activities both on earth, in fields as diverse as human health and the industrial production of novel bio-composites. Beyond earth, we will rely increasingly on biologically-provided life support, as we have throughout our evolutionary history. In order to do this, the field will build on two of the great contributions of astrobiology: studies of the origin of life and life in extreme environments.

  18. Synthetic Astrobiology

    Science.gov (United States)

    Rothschild, Lynn J.

    2015-01-01

    Synthetic biology - the design and construction of new biological parts and systems and the redesign of existing ones for useful purposes - has the potential to transform fields from pharmaceuticals to fuels. Our lab has focused on the potential of synthetic biology to revolutionize all three major parts of astrobiology: Where do we come from? Where are we going? and Are we alone? For the first and third, synthetic biology is allowing us to answer whether the evolutionary narrative that has played out on planet earth is likely to have been unique or universal. For example, in our lab we are re-evolving the biosynthetic pathways of amino acids in order to understand potential capabilities of an early organism with a limited repertoire of amino acids and developing techniques for the recovery of metals from spent electronics on other planetary bodies. In the future synthetic biology will play an increasing role in human activities both on earth, in fields as diverse as human health and the industrial production of novel bio-composites. Beyond earth, we will rely increasingly on biologically-provided life support, as we have throughout our evolutionary history. In order to do this, the field will build on two of the great contributions of astrobiology: studies of the origin of life and life in extreme environments.

  19. In vivo demonstration of reflection artifact reduction in photoacoustic imaging using synthetic aperture photoacoustic-guided focused ultrasound (PAFUSion)

    NARCIS (Netherlands)

    Kuniyil Ajith Singh, M.; Jaeger, M.; Frenz, M.; Steenbergen, W.

    2016-01-01

    Reflection artifacts caused by acoustic inhomogeneities are a critical problem in epi-mode biomedical photoacoustic imaging. High light fluence beneath the probe results in photoacoustic transients, which propagate into the tissue and reflect back from echogenic structures. These reflection artifact

  20. Detection of Flooded Areas in a Time Series of High Resolution Synthetic Aperture Radar Images using Curvelet Transform and Unsupervised Classification.

    Science.gov (United States)

    Ajadi, O. A.; Meyer, F. J.; Liljedahl, A. K.

    2016-12-01

    Due to their weather and illumination independence and due to their large area coverage at high spatial resolution, Synthetic Aperture Radar (SAR) images have been recognized as a valuable data source for the mapping and tracking of flooding events. In order to optimize mapping accuracy, a SAR-based flood detection approach should provide the following features: (1) due to the recent increase of flood situations and the rising number of high-resolution SAR datasets that require rapid processing, the generation of flood maps should be accomplished automatically and with robust results; (2) due to the large spatial extent of many recent flooding events, a flood detection approach should be computationally efficient and transferable to different environmental conditions (surface cover; scene heterogeneity) and data types. Considering these requirements and to improve upon the current state-of-the-art, we propose an unsupervised flood detection approach that is based on a time-series analysis of multi-temporal SAR images. Due to the inclusion of geometric and radiometric terrain correction, our method automatically adapts to changing environmental parameters. To preserve the full resolution of the original SAR data while reducing the influence of Speckle on flood detection performance, we integrate several recent image processing developments in our approach: We use curvelet filtering methods to suppress noise while preserving most relevant image details. Similarly, we perform a multi-scale decomposition of the input images to generate image instances with varying resolutions and signal-to-noise ratios. Finally, to increase the robustness to false alarms, we incorporate time-series analysis techniques in our workflow: We first generate a redundant set of change probability maps from a stack of repeated SAR images and then invert this redundant set using least-square techniques to arrive at the most likely time series of surface change. To demonstrate the performance of

  1. On reduction of risks in UXO and mine detection using remote sensing systems and related synthetic image simulation

    Science.gov (United States)

    Bostater, Charles R., Jr.

    2005-06-01

    It is important to understand remote sensing systems and associated platforms in the context of autonomous or semi-autonomous designs for (robotic & mechatronics) that may be affect the motion control or stabilization aspects of the imagery, scan lines or fixed points scanned. This need can be most easily conceived as being related to the reduction of risks associated with false detection as well as the risks associated with hardware and software failure and risks associated with the actual operation of sensor and platform in dangerous environments. Thus safety is ultimately our concern when it comes to risk assessment. This paper will describe (a) remote sensing systems, (b) platforms (fixed and mobile, as well as to demonstrate (c) the value of thinking in terms of scalability as well as modularity in the design and application of new systems and (d) creation of synthetic signatures obtained for detection of targets in the aquatic environment. New systems - sensing systems as well as autonomous or semiautonomous robotic and mechatronic systems will be essential to secure domestic preparedness for humanitarian reasons as well as for demining and UXO detection. These same systems hold tremendous value, if thoughtfully designed for other applications which include environmental monitoring and surveillance.

  2. Native iron

    DEFF Research Database (Denmark)

    Brooks, Charles Kent

    2015-01-01

    , a situation unique in the Solar System. In such a world, iron metal is unstable and, as we all know, oxidizes to the ferric iron compounds we call 'rust'. If we require iron metal it must be produced at high temperatures by reacting iron ore, usually a mixture of ferrous (Fe2+) and ferric (Fe3+) oxides (Fe2O3......, hematite, or FeO.Fe2O3, magnetite), with carbon in the form of coke. This is carried out in a blast furnace. Although the Earth's core consists of metallic iron, which may also be present in parts of the mantle, this is inaccessible to us, so we must make our own. In West Greenland, however, some almost...... unique examples of iron metal, otherwise called 'native iron' or 'telluric iron', occur naturally....

  3. Synthetic chromosomes.

    Science.gov (United States)

    Schindler, Daniel; Waldminghaus, Torsten

    2015-11-01

    What a living organism looks like and how it works and what are its components-all this is encoded on DNA, the genetic blueprint. Consequently, the way to change an organism is to change its genetic information. Since the first pieces of recombinant DNA have been used to transform cells in the 1970s, this approach has been enormously extended. Bigger and bigger parts of the genetic information have been exchanged or added over the years. Now we are at a point where the construction of entire chromosomes becomes a reachable goal and first examples appear. This development leads to fundamental new questions, for example, about what is possible and desirable to build or what construction rules one needs to follow when building synthetic chromosomes. Here we review the recent progress in the field, discuss current challenges and speculate on the appearance of future synthetic chromosomes.

  4. Investigating Cardiac Motion Patterns Using Synthetic High-Resolution 3D Cardiovascular Magnetic Resonance Images and Statistical Shape Analysis

    Science.gov (United States)

    Biffi, Benedetta; Bruse, Jan L.; Zuluaga, Maria A.; Ntsinjana, Hopewell N.; Taylor, Andrew M.; Schievano, Silvia

    2017-01-01

    Diagnosis of ventricular dysfunction in congenital heart disease is more and more based on medical imaging, which allows investigation of abnormal cardiac morphology and correlated abnormal function. Although analysis of 2D images represents the clinical standard, novel tools performing automatic processing of 3D images are becoming available, providing more detailed and comprehensive information than simple 2D morphometry. Among these, statistical shape analysis (SSA) allows a consistent and quantitative description of a population of complex shapes, as a way to detect novel biomarkers, ultimately improving diagnosis and pathology understanding. The aim of this study is to describe the implementation of a SSA method for the investigation of 3D left ventricular shape and motion patterns and to test it on a small sample of 4 congenital repaired aortic stenosis patients and 4 age-matched healthy volunteers to demonstrate its potential. The advantage of this method is the capability of analyzing subject-specific motion patterns separately from the individual morphology, visually and quantitatively, as a way to identify functional abnormalities related to both dynamics and shape. Specifically, we combined 3D, high-resolution whole heart data with 2D, temporal information provided by cine cardiovascular magnetic resonance images, and we used an SSA approach to analyze 3D motion per se. Preliminary results of this pilot study showed that using this method, some differences in end-diastolic and end-systolic ventricular shapes could be captured, but it was not possible to clearly separate the two cohorts based on shape information alone. However, further analyses on ventricular motion allowed to qualitatively identify differences between the two populations. Moreover, by describing shape and motion with a small number of principal components, this method offers a fully automated process to obtain visually intuitive and numerical information on cardiac shape and motion

  5. Learning Change from Synthetic Aperture Radar Images: Performance Evaluation of a Support Vector Machine to Detect Earthquake and Tsunami-Induced Changes

    Directory of Open Access Journals (Sweden)

    Marc Wieland

    2016-09-01

    Full Text Available This study evaluates the performance of a Support Vector Machine (SVM classifier to learn and detect changes in single- and multi-temporal X- and L-band Synthetic Aperture Radar (SAR images under varying conditions. The purpose is to provide guidance on how to train a powerful learning machine for change detection in SAR images and to contribute to a better understanding of potentials and limitations of supervised change detection approaches. This becomes particularly important on the background of a rapidly growing demand for SAR change detection to support rapid situation awareness in case of natural disasters. The application environment of this study thus focuses on detecting changes caused by the 2011 Tohoku earthquake and tsunami disaster, where single polarized TerraSAR-X and ALOS PALSAR intensity images are used as input. An unprecedented reference dataset of more than 18,000 buildings that have been visually inspected by local authorities for damages after the disaster forms a solid statistical population for the performance experiments. Several critical choices commonly made during the training stage of a learning machine are being assessed for their influence on the change detection performance, including sampling approach, location and number of training samples, classification scheme, change feature space and the acquisition dates of the satellite images. Furthermore, the proposed machine learning approach is compared with the widely used change image thresholding. The study concludes that a well-trained and tuned SVM can provide highly accurate change detections that outperform change image thresholding. While good performance is achieved in the binary change detection case, a distinction between multiple change classes in terms of damage grades leads to poor performance in the tested experimental setting. The major drawback of a machine learning approach is related to the high costs of training. The outcomes of this study, however

  6. Method of moving target detection based on sub-image cancellation for single-antenna airborne synthetic aperture radar

    Institute of Scientific and Technical Information of China (English)

    2007-01-01

    The method of moving target detection based on subimage cancellation for single-antenna airborne SAR is presented.First the subimage is obtained through frequency processing is pointed out.The imaging difference of a stationary objects and moving object in the subimage based on the frequency division is analyzed from the fundamental principle.Then the developed method combines the shear averaging algorithm to focus on the moving target in the subimage,after the clutter suppression and the focusing position in each subimage is obtained.Next the observation model and the relative movement of the moving targets between the subimages estimate the moving targets.The theoretical analysis and simulation results demonstrate that the method is effective and can not only detect the moving targets,but also estimate their motion parameters precisely.

  7. Native Americans with Diabetes

    Science.gov (United States)

    ... Read the MMWR Science Clips Native Americans with Diabetes Better diabetes care can decrease kidney failure Language: ... between 1996 and 2013. Problem Kidney failure from diabetes was highest among Native Americans. Native Americans are ...

  8. Synthetic Cannabinoids.

    Science.gov (United States)

    Mills, Brooke; Yepes, Andres; Nugent, Kenneth

    2015-07-01

    Synthetic cannabinoids (SCBs), also known under the brand names of "Spice," "K2," "herbal incense," "Cloud 9," "Mojo" and many others, are becoming a large public health concern due not only to their increasing use but also to their unpredictable toxicity and abuse potential. There are many types of SCBs, each having a unique binding affinity for cannabinoid receptors. Although both Δ-tetrahydrocannabinol (THC) and SCBs stimulate the same receptors, cannabinoid receptor 1 (CB1) and cannabinoid receptor 2 (CB2), studies have shown that SCBs are associated with higher rates of toxicity and hospital admissions than is natural cannabis. This is likely due to SCBs being direct agonists of the cannabinoid receptors, whereas THC is a partial agonist. Furthermore, the different chemical structures of SCBs found in Spice or K2 may interact in unpredictable ways to elicit previously unknown, and the commercial products may have unknown contaminants. The largest group of users is men in their 20s who participate in polydrug use. The most common reported toxicities with SCB use based on studies using Texas Poison Control records are tachycardia, agitation and irritability, drowsiness, hallucinations, delusions, hypertension, nausea, confusion, dizziness, vertigo and chest pain. Acute kidney injury has also been strongly associated with SCB use. Treatment mostly involves symptom management and supportive care. More research is needed to identify which contaminants are typically found in synthetic marijuana and to understand the interactions between different SBCs to better predict adverse health outcomes.

  9. Natural - synthetic - artificial!

    DEFF Research Database (Denmark)

    Nielsen, Peter E

    2010-01-01

    The terms "natural," "synthetic" and "artificial" are discussed in relation to synthetic and artificial chromosomes and genomes, synthetic and artificial cells and artificial life.......The terms "natural," "synthetic" and "artificial" are discussed in relation to synthetic and artificial chromosomes and genomes, synthetic and artificial cells and artificial life....

  10. Diagnostic Magnetic Resonance Imaging of Atherosclerosis in Apolipoprotein E Knockout Mouse Model Using Macrophage-Targeted Gadolinium-Containing Synthetic Lipopeptide Nanoparticles

    Science.gov (United States)

    Shen, Zu T.; Zheng, Shaokuan; Gounis, Matthew J.; Sigalov, Alexander B.

    2015-01-01

    Cardiovascular disease is the leading cause of death in Western cultures. The vast majority of cardiovascular events, including stroke and myocardial infarction, result from the rupture of vulnerable atherosclerotic plaques, which are characterized by high and active macrophage content. Current imaging modalities including magnetic resonance imaging (MRI) aim to characterize anatomic and structural features of plaques rather than their content. Previously, we reported that macrophage-targeted delivery of gadolinium (Gd)-based contrast agent (GBCA-HDL) using high density lipoproteins (HDL)-like particles significantly enhances the detection of plaques in an apolipoprotein (apo) E knockout (KO) mouse model, with an atherosclerotic wall/muscle normalized enhancement ratio (NER) of 120% achieved. These particles are comprised of lipids and synthetic peptide fragments of the major protein of HDL, apo A-I, that contain a naturally occurring modification which targets the particles to macrophages. Targeted delivery minimizes the Gd dose and thus reduces the adverse effects of Gd. The aims of the current study were to test whether varying the GBCA-HDL particle shape and composition can further enhance atherosclerotic plaque MRI and control organ clearance of these agents. We show that the optimized GBCA-HDL particles are efficiently delivered intracellularly to and uptaken by both J774 macrophages in vitro and more importantly, by intraplaque macrophages in vivo, as evidenced by NER up to 160% and higher. This suggests high diagnostic power of our GBCA-HDL particles in the detection of vulnerable atherosclerotic plaques. Further, in contrast to discoidal, spherical GBCA-HDL exhibit hepatic clearance, which could further diminish adverse renal effects of Gd. Finally, activated macrophages are reliable indicators of any inflamed tissues and are implicated in other areas of unmet clinical need such as rheumatoid arthritis, sepsis and cancer, suggesting the expanded diagnostic

  11. Diagnostic Magnetic Resonance Imaging of Atherosclerosis in Apolipoprotein E Knockout Mouse Model Using Macrophage-Targeted Gadolinium-Containing Synthetic Lipopeptide Nanoparticles.

    Directory of Open Access Journals (Sweden)

    Zu T Shen

    Full Text Available Cardiovascular disease is the leading cause of death in Western cultures. The vast majority of cardiovascular events, including stroke and myocardial infarction, result from the rupture of vulnerable atherosclerotic plaques, which are characterized by high and active macrophage content. Current imaging modalities including magnetic resonance imaging (MRI aim to characterize anatomic and structural features of plaques rather than their content. Previously, we reported that macrophage-targeted delivery of gadolinium (Gd-based contrast agent (GBCA-HDL using high density lipoproteins (HDL-like particles significantly enhances the detection of plaques in an apolipoprotein (apo E knockout (KO mouse model, with an atherosclerotic wall/muscle normalized enhancement ratio (NER of 120% achieved. These particles are comprised of lipids and synthetic peptide fragments of the major protein of HDL, apo A-I, that contain a naturally occurring modification which targets the particles to macrophages. Targeted delivery minimizes the Gd dose and thus reduces the adverse effects of Gd. The aims of the current study were to test whether varying the GBCA-HDL particle shape and composition can further enhance atherosclerotic plaque MRI and control organ clearance of these agents. We show that the optimized GBCA-HDL particles are efficiently delivered intracellularly to and uptaken by both J774 macrophages in vitro and more importantly, by intraplaque macrophages in vivo, as evidenced by NER up to 160% and higher. This suggests high diagnostic power of our GBCA-HDL particles in the detection of vulnerable atherosclerotic plaques. Further, in contrast to discoidal, spherical GBCA-HDL exhibit hepatic clearance, which could further diminish adverse renal effects of Gd. Finally, activated macrophages are reliable indicators of any inflamed tissues and are implicated in other areas of unmet clinical need such as rheumatoid arthritis, sepsis and cancer, suggesting the

  12. Synthetic Astrobiology

    Science.gov (United States)

    Rothschild, Lynn J.

    2017-01-01

    "Are we alone?" is one of the primary questions of astrobiology, and whose answer defines our significance in the universe. Unfortunately, this quest is hindered by the fact that we have only one confirmed example of life, that of earth. While this is enormously helpful in helping to define the minimum envelope for life, it strains credulity to imagine that life, if it arose multiple times, has not taken other routes. To help fill this gap, our lab has begun using synthetic biology - the design and construction of new biological parts and systems and the redesign of existing ones for useful purposes - as an enabling technology. One theme, the "Hell Cell" project, focuses on creating artificial extremophiles in order to push the limits for Earth life, and to understand how difficult it is for life to evolve into extreme niches. In another project, we are re-evolving biotic functions using only the most thermodynamically stable amino acids in order to understand potential capabilities of an early organism with a limited repertoire of amino acids.

  13. Efficient automated one-step synthesis of 2-[{sup 18}F]fluoroethylcholine for clinical imaging: optimized reaction conditions and improved quality controls of different synthetic approaches

    Energy Technology Data Exchange (ETDEWEB)

    Asti, Mattia [Nuclear Medicine Department, Santa Maria Nuova Hospital, Reggio Emilia (Italy)], E-mail: asti.mattia@asmn.re.it; Farioli, Daniela; Iori, Michele; Guidotti, Claudio; Versari, Annibale; Salvo, Diana [Nuclear Medicine Department, Santa Maria Nuova Hospital, Reggio Emilia (Italy)

    2010-04-15

    [{sup 18}F]-labelled choline analogues, such as 2-[{sup 18}F]fluoroethylcholine ({sup 18}FECH), have suggested to be a new class of choline derivatives highly useful for the imaging of prostate and brain tumours. In fact, tumour cells with enhanced proliferation rate usually exhibit an improved choline uptake due to the increased membrane phospholipids biosynthesis. The aim of this study was the development of a high yielding synthesis of {sup 18}FECH. The possibility of shortening the synthesis time by reacting all the reagents in a convenient and rapid one-step reaction was specially considered. Methods: {sup 18}FECH was synthesized by reacting [{sup 18}F]fluoride with 1,2-bis(tosyloxy)ethane and N,N-dimethylaminoethanol. The synthesis was carried out using both a one- and a two-step reaction in order to compare the two procedures. The effects on the radiochemical yield and purity by using different [{sup 18}F]fluoride phase transfer catalysts, reagents amounts and purification methods were assessed. Quality controls on the final products were performed by means of radio-thin-layer chromatography, gas chromatography and high-performance liquid chromatography equipped with conductimetric, ultraviolet and radiometric detectors. Results: In the optimized experimental conditions, {sup 18}FECH was synthesized with a radiochemical yield of 43{+-}3% and 48{+-}1% (not corrected for decay) when the two-step or the one-step approach were used, respectively. The radiochemical purity was higher than 99% regardless of the different synthetic pathways or purification methods adopted. The main chemical impurity was due to N,N-dimethylmorpholinium. The identity of this impurity in {sup 18}FECH preparations was not previously reported. Conclusion: An improved two-step and an innovative one-step reaction for synthesizing {sup 18}FECH in a high yield were reported. The adaptation of a multistep synthesis to a single step process, opens further possibilities for simpler and more

  14. Synthetic Aperture Radar - Hardware Development

    Directory of Open Access Journals (Sweden)

    V. Rosner

    2009-06-01

    Full Text Available Experimental real and synthetic aperture radar are developed from the base-band digital unit to the analogue RF parts, based on solid state units, using pulse compression for radar imaging. Proper QPSK code is found for matched filter.

  15. Native Health Research Database

    Science.gov (United States)

    ... APP WITH JAVASCRIPT TURNED OFF. THE NATIVE HEALTH DATABASE REQUIRES JAVASCRIPT IN ORDER TO FUNCTION. PLEASE ENTER ... To learn more about searching the Native Health Database, click here. Keywords Title Author Source of Publication ...

  16. Synthetic MRI of the brain in a clinical setting

    Energy Technology Data Exchange (ETDEWEB)

    Blystad, I.; Smedby, O. [Center for Medical Image Science and Visualization, CMIV, Linkoeping University, Linkoeping (Sweden); Radiology, Department of Medical and Health Sciences, Linkoeping University, Department of Radiology, UHL, County Council of Oestergoetland, Linkoeping (Sweden)], E-mail: ida.blystad@lio.se; Warntjes, J.B.M. [Center for Medical Image Science and Visualization, CMIV, Linkoeping University, Linkoeping (Sweden); Clinical Physiology, Department of Medical and Health Sciences, Linkoeping University, Department of Clinical Physiology, UHL, County Council of Oestergoetland, Linkoeping (Sweden); Landtblom, A.-M. [Center for Medical Image Science and Visualization, CMIV, Linkoeping University, Linkoeping (Sweden); Neurology, Department of Clinical and Experimental Medicine, Linkoeping University, Division of Neurology, UHL, LiM, County Council of Oestergoetland, Linkoeping (Sweden); Lundberg, P. [Center for Medical Image Science and Visualization, CMIV, Linkoeping University, Linkoeping (Sweden); Radiation Physics, Department of Medical and Health Sciences, Linkoeping University, Department of Radiation Physics, UHL, County Council of Oestergoetland, Linkoeping (Sweden); Larsson, E.-M. [Center for Medical Image Science and Visualization, CMIV, Linkoeping University, Linkoeping (Sweden); Department of Radiology, Oncology and Radiation Science/Radiology, Uppsala University, Uppsala (Sweden)

    2012-12-15

    Background. Conventional magnetic resonance imaging (MRI) has relatively long scan times for routine examinations, and the signal intensity of the images is related to the specific MR scanner settings. Due to scanner imperfections and automatic optimizations, it is impossible to compare images in terms of absolute image intensity. Synthetic MRI, a method to generate conventional images based on MR quantification, potentially both decreases examination time and enables quantitative measurements. Purpose. To evaluate synthetic MRI of the brain in a clinical setting by assessment of the contrast, the contrast-to-noise ratio (CNR), and the diagnostic quality compared with conventional MR images. Material and Methods. Twenty-two patients had synthetic imaging added to their clinical MR examination. In each patient, 12 regions of interest were placed in the brain images to measure contrast and CNR. Furthermore, general image quality, probable diagnosis, and lesion conspicuity were investigated. Results. Synthetic T1-weighted turbo spin echo and T2-weighted turbo spin echo images had higher contrast but also a higher level of noise, resulting in a similar CNR compared with conventional images. Synthetic T2-weighted FLAIR images had lower contrast and a higher level of noise, which led to a lower CNR. Synthetic images were generally assessed to be of inferior image quality, but agreed with the clinical diagnosis to the same extent as the conventional images. Lesion conspicuity was higher in the synthetic T1-weighted images, which also had a better agreement with the clinical diagnoses than the conventional T1-weighted images. Conclusion. Synthetic MR can potentially shorten the MR examination time. Even though the image quality is perceived to be inferior, synthetic images agreed with the clinical diagnosis to the same extent as the conventional images in this study.

  17. 地下介质和物流运移的综合成像方案%Imaging Synthetic Scheme for Underground Medium and Material-transport

    Institute of Scientific and Technical Information of China (English)

    郭履灿

    2003-01-01

    目的:借鉴比较方法论,为研究天气过程的三维成像和在三维动态天气过程的基础上,所发展的描述冷暖气流等多种参数(气压、温度和湿度、风速、风向、水蒸汽密度等)的动态三维显示,初步解决了暴雨和天气预报的难题,促进了天气预报的成功,在地球科学中起到了示范作用.从而联想到在地下介质和物流运移过程的综合成像.资料和方法:本文总结了地面和地下探测手段的多样性,列举了天然地震CT的精度已能达到1~5km的量级,地震人工爆破作勘探可以达到10~20米的成像分辨率,地下电阻率和电磁成像可以分辨到1~2米的量级;将磁共振(MRI)用于地下成像可得到地下水分布的动态观测深度,概括了这三方面的前沿性进展,并与震源的空间分布和地应力相结合,进而设计出综合性的观测系统.发展地下水、岩浆、地应力和活断层结构和地震破裂面等多种参数的动态显示,设计出一套观测系统,并阐述它的科学意义.结果和结论:将以上三方面的观测方法综合起来:可在有火山喷发危险的区域、具有诱发地震危险的大型水库地区,和在发生了强烈地震的地区,为了抗震救灾,有必要同时进行以上三个系统的观测,引入可视化数字科技,便于了解地下水和岩浆的运移过程及相关参数的变化,并配合当前已有的综合监测系统(震源空间分布、地震应力和其他前兆等),服务于保障大型水库的安全、促进强震预测,及对火山喷发、矿井塌陷、突出的监测预报.%Objective: Making reference to the development of weather forecast and increasing meteorological parameter in weather predication process, the author provide an Imaging Synthetic Scheme for underground material-transport, by introducing the comparison methodology. This synthetic scheme may including to explore the seismic active faults, to reveal some basic characteristics of

  18. NATIVE VS NON-NATIVE ENGLISH TEACHERS

    Directory of Open Access Journals (Sweden)

    Masrizal Masrizal

    2013-02-01

    Full Text Available Although the majority of English language teachers worldwide are non-native English speakers (NNS, no research was conducted on these teachers until recently. A pioneer research by Peter Medgyes in 1994 took quite a long time until the other researchers found their interests in this issue. There is a widespread stereotype that a native speaker (NS is by nature the best person to teach his/her foreign language. In regard to this assumption, we then see a very limited room and opportunities for a non native teacher to teach language that is not his/hers. The aim of this article is to analyze the differences among these teachers in order to prove that non-native teachers have equal advantages that should be taken into account. The writer expects that the result of this short article could be a valuable input to the area of teaching English as a foreign language in Indonesia.

  19. Space noise synthetic aperture radar

    Science.gov (United States)

    Kulpa, Krzysztof S.

    2006-03-01

    The paper presents limitations of space borne synthetic aperture radars, caused by range and Doppler velocity ambiguities, and the concept of usage of the noise radar technology for creation of high-resolution space SAR images. The noise SAR is free from limitation caused by the periodicity of pulse waveform ambiguity function, and therefore this technology can be used in the future space missions. The basic concept of noise SAR image formation is also presented. The image formation algorithm has been verified using the simulated data produced by Raw Radar Data Simulator.

  20. Synthetic Hounsfield units from spectral CT data

    Science.gov (United States)

    Bornefalk, Hans

    2012-04-01

    Beam-hardening-free synthetic images with absolute CT numbers that radiologists are used to can be constructed from spectral CT data by forming ‘dichromatic’ images after basis decomposition. The CT numbers are accurate for all tissues and the method does not require additional reconstruction. This method prevents radiologists from having to relearn new rules-of-thumb regarding absolute CT numbers for various organs and conditions as conventional CT is replaced by spectral CT. Displaying the synthetic Hounsfield unit images side-by-side with images reconstructed for optimal detectability for a certain task can ease the transition from conventional to spectral CT.

  1. Learning from biology: synthetic lipoproteins for drug delivery.

    Science.gov (United States)

    Huang, Huang; Cruz, William; Chen, Juan; Zheng, Gang

    2015-01-01

    Synthetic lipoproteins represent a relevant tool for targeted delivery of biological/chemical agents (chemotherapeutics, siRNAs, photosensitizers, and imaging contrast agents) into various cell types. These nanoparticles offer a number of advantages for drugs delivery over their native counterparts while retaining their natural characteristics and biological functions. Their ultra-small size (class B member 1 (SRB1) that are found in a number of pathological conditions (e.g., cancer, atherosclerosis), make them superior delivery strategies when compared with other nanoparticle systems. We review the various approaches that have been developed for the generation of synthetic lipoproteins and their respective applications in vitro and in vivo. More specifically, we summarize the approaches employed to address the limitation on use of reconstituted lipoproteins by means of natural or recombinant apolipoproteins, as well as apolipoprotein mimetic molecules. Finally, we provide an overview of the advantages and disadvantages of these approaches and discuss future perspectives for clinical translation of these nanoparticles. © 2014 Wiley Periodicals, Inc.

  2. Synthetic biology, inspired by synthetic chemistry.

    Science.gov (United States)

    Malinova, V; Nallani, M; Meier, W P; Sinner, E K

    2012-07-16

    The topic synthetic biology appears still as an 'empty basket to be filled'. However, there is already plenty of claims and visions, as well as convincing research strategies about the theme of synthetic biology. First of all, synthetic biology seems to be about the engineering of biology - about bottom-up and top-down approaches, compromising complexity versus stability of artificial architectures, relevant in biology. Synthetic biology accounts for heterogeneous approaches towards minimal and even artificial life, the engineering of biochemical pathways on the organismic level, the modelling of molecular processes and finally, the combination of synthetic with nature-derived materials and architectural concepts, such as a cellular membrane. Still, synthetic biology is a discipline, which embraces interdisciplinary attempts in order to have a profound, scientific base to enable the re-design of nature and to compose architectures and processes with man-made matter. We like to give an overview about the developments in the field of synthetic biology, regarding polymer-based analogs of cellular membranes and what questions can be answered by applying synthetic polymer science towards the smallest unit in life, namely a cell.

  3. MBS Native Plant Communities

    Data.gov (United States)

    Minnesota Department of Natural Resources — This data layer contains results of the Minnesota County Biological Survey (MCBS). It includes polygons representing the highest quality native plant communities...

  4. Plant synthetic biology.

    Science.gov (United States)

    Liu, Wusheng; Stewart, C Neal

    2015-05-01

    Plant synthetic biology is an emerging field that combines engineering principles with plant biology toward the design and production of new devices. This emerging field should play an important role in future agriculture for traditional crop improvement, but also in enabling novel bioproduction in plants. In this review we discuss the design cycles of synthetic biology as well as key engineering principles, genetic parts, and computational tools that can be utilized in plant synthetic biology. Some pioneering examples are offered as a demonstration of how synthetic biology can be used to modify plants for specific purposes. These include synthetic sensors, synthetic metabolic pathways, and synthetic genomes. We also speculate about the future of synthetic biology of plants.

  5. Synthetic Cathinones ("Bath Salts")

    Science.gov (United States)

    ... A recent study found that 3,4-methylenedioxypyrovalerone (MDPV), a common synthetic cathinone, affects the brain in ... but is at least 10 times more powerful. MDPV is the most common synthetic cathinone found in ...

  6. What Are Synthetic Cannabinoids?

    Science.gov (United States)

    ... dried plant materials. Chemical tests show that their active ingredients are man-made cannabinoid compounds. Synthetic cannabinoid users report some effects similar to those produced by marijuana: elevated mood relaxation altered perception symptoms of psychosis Synthetic cannabinoids can ...

  7. Application of Synthetic Satellite Image of SPOT and TM D ata in Debris Flow Investigation%陆地卫星SPOT、TM数据复合影象在泥石流调查中的应用

    Institute of Scientific and Technical Information of China (English)

    白志勇

    2001-01-01

    The article made synthetic image with rich colour and higherresolvi ng power out of satellite data of SPOT and TM, and extracted spectral informatio n characteristic and geologic body image characteristic. According to it, we dis tinguished and examined debris flow of the main ditch, and found its movi ng characteristic and developing trend.%将陆地卫星SPOT数据及TM数据进行复合,制成具有丰富色彩和较高分辨力的复合影象图,提取其光谱信息特征和地质体影纹特征。据此,对干沟泥石流进行判释和验证,查清了干沟泥石流运动特点及发展趋势。

  8. Synthetic aperture radar capabilities in development

    Energy Technology Data Exchange (ETDEWEB)

    Miller, M. [Lawrence Livermore National Lab., CA (United States)

    1994-11-15

    The Imaging and Detection Program (IDP) within the Laser Program is currently developing an X-band Synthetic Aperture Radar (SAR) to support the Joint US/UK Radar Ocean Imaging Program. The radar system will be mounted in the program`s Airborne Experimental Test-Bed (AETB), where the initial mission is to image ocean surfaces and better understand the physics of low grazing angle backscatter. The Synthetic Aperture Radar presentation will discuss its overall functionality and a brief discussion on the AETB`s capabilities. Vital subsystems including radar, computer, navigation, antenna stabilization, and SAR focusing algorithms will be examined in more detail.

  9. Synthetic diagnostics platform for fusion plasmas (invited)

    Energy Technology Data Exchange (ETDEWEB)

    Shi, L., E-mail: lshi@pppl.gov; Valeo, E. J.; Tobias, B. J.; Kramer, G. J.; Hausammann, L.; Tang, W. M. [Princeton Plasma Physics Laboratory, Princeton, New Jersey 08540 (United States); Chen, M. [Department of Mechanical and Aerospace Engineering, University of California, Davis, California 95616 (United States)

    2016-11-15

    A Synthetic Diagnostics Platform (SDP) for fusion plasmas has been developed which provides state of the art synthetic reflectometry, beam emission spectroscopy, and Electron Cyclotron Emission (ECE) diagnostics. Interfaces to the plasma simulation codes GTC, XGC-1, GTS, and M3D-C{sup 1} are provided, enabling detailed validation of these codes. In this paper, we give an overview of SDP’s capabilities, and introduce the synthetic diagnostic modules. A recently developed synthetic ECE Imaging module which self-consistently includes refraction, diffraction, emission, and absorption effects is discussed in detail. Its capabilities are demonstrated on two model plasmas. The importance of synthetic diagnostics in validation is shown by applying the SDP to M3D-C{sup 1} output and comparing it with measurements from an edge harmonic oscillation mode on DIII-D.

  10. Listen to the Natives

    Science.gov (United States)

    Prensky, Marc

    2006-01-01

    "Digital natives" refer to today's students because they are native speakers of technology, fluent in the digital language of computers, video games, and the Internet. Those who were not born into the digital world are referred to as digital immigrants. Educators, considered digital immigrants, have slid into the 21st century--and into the digital…

  11. Shadow Enhancement in Synthetic Aperture Sonar Using Fixed Focusing

    NARCIS (Netherlands)

    Groen, J.; Hansen, R.E.; Callow, H.J.; Sabel, J.C.; Sæbø, T.O.

    2009-01-01

    Abstract—A shadow cast by an object on the seafloor is important information for target recognition in synthetic aperture sonar (SAS) images. Synthetic aperture imaging causes a fundamental limitation to shadow clarity because the illuminator is moved during the data collection. This leads to a blen

  12. Using organic fertilizers in forest and native plant nurseries

    Science.gov (United States)

    Thomas D. Landis; R. Kasten Dumroese

    2012-01-01

    Since World War II, synthetic fertilizers have been used almost exclusively to grow forest and native plant nursery crops because they are quickly soluble and readily taken up by crops, producing the rapid growth rates that are necessary in nursery culture. In recent years, however, a wide variety of new organic fertilizers have become available. We divided these...

  13. Cryo-FIB-SEM serial milling and block face imaging: Large volume structural analysis of biological tissues preserved close to their native state.

    Science.gov (United States)

    Vidavsky, Netta; Akiva, Anat; Kaplan-Ashiri, Ifat; Rechav, Katya; Addadi, Lia; Weiner, Steve; Schertel, Andreas

    2016-12-01

    Many important biological questions can be addressed by studying in 3D large volumes of intact, cryo fixed hydrated tissues (⩾10,000μm(3)) at high resolution (5-20nm). This can be achieved using serial FIB milling and block face surface imaging under cryo conditions. Here we demonstrate the unique potential of the cryo-FIB-SEM approach using two extensively studied model systems; sea urchin embryos and the tail fin of zebrafish larvae. We focus in particular on the environment of mineral deposition sites. The cellular organelles, including mitochondria, Golgi, ER, nuclei and nuclear pores are made visible by the image contrast created by differences in surface potential of different biochemical components. Auto segmentation and/or volume rendering of the image stacks and 3D reconstruction of the skeleton and the cellular environment, provides a detailed view of the relative distribution in space of the tissue/cellular components, and thus of their interactions. Simultaneous acquisition of secondary and back-scattered electron images adds additional information. For example, a serial view of the zebrafish tail reveals the presence of electron dense mineral particles inside mitochondrial networks extending more than 20μm in depth in the block. Large volume imaging using cryo FIB SEM, as demonstrated here, can contribute significantly to the understanding of the structures and functions of diverse biological tissues.

  14. 菲涅耳望远镜合成孔径激光成像雷达实验室验证%Demonstration of a Laboratory Fresnel Telescope Synthetic Aperture Imaging Ladar

    Institute of Scientific and Technical Information of China (English)

    戴恩文; 孙建锋; 闫爱民; 职亚楠; 周煜; 吴亚鹏; 刘立人

    2012-01-01

    A laboratory demonstration of Fresnel telescope synthetic aperture imaging ladar system is presented. The target is two-dimensional (2D) scanned by a beam that is combined by two concentric and coaxial quadratic wavefont laser beams with orthogonal polarization. The scattered signal light from the target is collected by a telescope and is split into two beams by a polarized beamsplitter. The two separated beams then pass through a ha'.f and quarter waveplate, respectively, and enter a 90 degree 2×4 optical hybrid. The four outputs of optical signals from optical hybrid are detected by two pairs of balanced detectors and then stored in computer using AD converters. The image of the target can be reconstructed from the data acquired by 2D scanning through data processing. A point image of 0. 3 mm× 0. 3 mm and 2D Chinese character are reconstructed in experiments with high resolution and contrast. The expected speckles are also observed in the reconstructed image that commonly existed in coherent imaging. The experimental results prove the correctness of the concept of the Fresnel telescope synthetic aperture imaging ladar.%对菲涅耳望远镜合成孔径激光成像雷达进行了实验室尺度条件下的原理验证实验.实验中利用不同曲率半径、垂直正交偏振的两个球面波通过二维(2D)扫描方式照明远距离处的目标,接收望远镜接收到的目标回波经过偏振分光镜分成两束作为信号光和本振光进入2×4 90°桥接器,桥接器输出的四路光信号被两个平衡探测器接收,平衡探测器输出电信号经模数转换后经过复数化、两维相位二次项匹配滤波算法处理后可以重构出目标图像.对4.3 m处点目标和2D面目标进行了成像实验,取得了具有良好成像分辨率和对比度且带有散斑效应的预期成像结果,证明了该合成成像激光雷达概念的正确性.

  15. Validation and Sensitivity Analysis of 3D Synthetic Aperture Radar (SAR) Imaging of the Interior of Primitive Solar System Bodies: Comets and Asteroids Project

    Data.gov (United States)

    National Aeronautics and Space Administration — To probe the interior of a comet, we are going to employ Radar Reflection Imager (RRI) Instrument on an orbiting platform. While orbiting around the comet at a safe...

  16. [From synthetic biology to synthetic humankind].

    Science.gov (United States)

    Nouvel, Pascal

    2015-01-01

    In this paper, we propose an historical survey of the expression "synthetic biology" in order to identify its main philosophical components. The result of the analysis is then used to investigate the meaning of the notion of "synthetic man". It is shown that both notions share a common philosophical background that can be summed up by the short but meaningful assertion: "biology is technology". The analysis allows us to distinguish two notions that are often confused in transhumanist literature: the notion of synthetic man and the notion of renewed man. The consequences of this crucial distinction are discussed. Copyright © 2015 Académie des sciences. Published by Elsevier SAS. All rights reserved.

  17. Native grasslands fertilize themselves

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — News article about Lostwood National Wildlife Refuge and how the native soils and plants function to stimulate the system, creating a more productive grassland.

  18. Systems and synthetic biology approaches to alter plant cell walls and reduce biomass recalcitrance.

    Science.gov (United States)

    Kalluri, Udaya C; Yin, Hengfu; Yang, Xiaohan; Davison, Brian H

    2014-12-01

    Fine-tuning plant cell wall properties to render plant biomass more amenable to biofuel conversion is a colossal challenge. A deep knowledge of the biosynthesis and regulation of plant cell wall and a high-precision genome engineering toolset are the two essential pillars of efforts to alter plant cell walls and reduce biomass recalcitrance. The past decade has seen a meteoric rise in use of transcriptomics and high-resolution imaging methods resulting in fresh insights into composition, structure, formation and deconstruction of plant cell walls. Subsequent gene manipulation approaches, however, commonly include ubiquitous mis-expression of a single candidate gene in a host that carries an intact copy of the native gene. The challenges posed by pleiotropic and unintended changes resulting from such an approach are moving the field towards synthetic biology approaches. Synthetic biology builds on a systems biology knowledge base and leverages high-precision tools for high-throughput assembly of multigene constructs and pathways, precision genome editing and site-specific gene stacking, silencing and/or removal. Here, we summarize the recent breakthroughs in biosynthesis and remodelling of major secondary cell wall components, assess the impediments in obtaining a systems-level understanding and explore the potential opportunities in leveraging synthetic biology approaches to reduce biomass recalcitrance. Published 2014. This article is a U.S. Government work and is in the public domain in the USA. Plant Biotechnology Journal published by Society for Experimental Biology and The Association of Applied Biologists and John Wiley & Sons Ltd.

  19. Characterization of Synthetic Aperture Radar Image Features of the Ocean as a Function of Wind Speed and High Frequency Radar Products

    Science.gov (United States)

    2012-06-01

    the next sections, the method to obtain surface currents from CODAR-type HF radar is described. The process of attaining calibrated and geocoded SAR...n.d.). It’s not the same as geocoding , but does allow the user to have a reasonable interpretation of the SAR image before taking further steps...of a scene and the tilt of the satellite sensor (NEST User Manual, n.d.). The final product is a geocoded image in the projection chosen by the

  20. Evaluation of native hyaline cartilage and repair tissue after two cartilage repair surgery techniques with 23Na MR imaging at 7 T: initial experience.

    Science.gov (United States)

    Zbýň, S; Stelzeneder, D; Welsch, G H; Negrin, L L; Juras, V; Mayerhoefer, M E; Szomolanyi, P; Bogner, W; Domayer, S E; Weber, M; Trattnig, S

    2012-08-01

    To compare the sodium normalized mean signal intensity (NMSI) values between patients after bone marrow stimulation (BMS) and matrix-associated autologous chondrocyte transplantation (MACT) cartilage repair procedures. Nine BMS and nine MACT patients were included. Each BMS patient was matched with one MACT patient according to age [BMS 36.7 ± 10.7 (mean ± standard deviation) years; MACT 36.9 ± 10.0 years], postoperative interval (BMS 33.5 ± 25.3 months; MACT 33.2 ± 25.7 months), and defect location. All magnetic resonance imaging (MRI) measurements were performed on a 7 T system. Proton images served for morphological evaluation of repair tissue using the magnetic resonance observation of cartilage repair tissue (MOCART) scoring system. Sodium NMSI values in the repair area and morphologically normal cartilage were calculated. Clinical outcome was assessed right after MRI. Analysis of covariance, t-tests, and Pearson correlation coefficients were evaluated. Sodium NMSI was significantly lower in BMS (P = 0.004) and MACT (P = 0.006) repair tissue, compared to reference cartilage. Sodium NMSI was not different between the reference cartilage in MACT and BMS patients (P = 0.664), however it was significantly higher in MACT than in BMS repair tissue (P = 0.028). Better clinical outcome was observed in BMS than in MACT patients. There was no difference between MOCART scores for MACT and BMS patients (P = 0.915). We did not observe any significant correlation between MOCART score and sodium repair tissue NMSI (r = -0.001; P = 0.996). Our results suggest higher glycosaminoglycan (GAG) content, and therefore, repair tissue of better quality in MACT than in BMS patients. Sodium imaging might be beneficial in non-invasive evaluation of cartilage repair surgery efficacy. Copyright © 2012 Osteoarthritis Research Society International. Published by Elsevier Ltd. All rights reserved.

  1. Performance assessment of simulated 3D laser images using Geiger-mode avalanche photo-diode: tests on simple synthetic scenarios

    Science.gov (United States)

    Coyac, Antoine; Hespel, Laurent; Riviere, Nicolas; Briottet, Xavier

    2015-10-01

    In the past few decades, laser imaging has demonstrated its potential in delivering accurate range images of objects or scenes, even at long range or under bad weather conditions (rain, fog, day and night vision). We note great improvements in the conception and development of single and multi infrared sensors, concerning embedability, circuitry reading capacity, or pixel resolution and sensitivity, allowing a wide diversity of applications (i.e. enhanced vision, long distance target detection and reconnaissance, 3D DSM generation). Unfortunately, it is often difficult to dispose of all the instruments to compare their performance for a given application. Laser imaging simulation has shown to be an interesting alternative to acquire real data, offering a higher flexibility to perform this sensors comparison, plus being time and cost efficient. In this paper, we present a 3D laser imaging end-to-end simulator using a focal plane array with Geiger mode detection, named LANGDOC. This work aims to highlight the interest and capability of this new generation of photo-diodes arrays, especially for airborne mapping and surveillance of high risk areas.

  2. Synthetic range profiling, ISAR imaging of sea vessels and feature extraction, using a multimode radar to classify targets: initial results from field trials

    CSIR Research Space (South Africa)

    Abdul Gaffar, MY

    2011-04-01

    Full Text Available -based classification of small to medium sized sea vessels in littoral condition. The experimental multimode radar is based on an experimental tracking radar that was modified to generate SRP and ISAR images in both search and tracking modes. The architecture...

  3. Designing synthetic biology.

    Science.gov (United States)

    Agapakis, Christina M

    2014-03-21

    Synthetic biology is frequently defined as the application of engineering design principles to biology. Such principles are intended to streamline the practice of biological engineering, to shorten the time required to design, build, and test synthetic gene networks. This streamlining of iterative design cycles can facilitate the future construction of biological systems for a range of applications in the production of fuels, foods, materials, and medicines. The promise of these potential applications as well as the emphasis on design has prompted critical reflection on synthetic biology from design theorists and practicing designers from many fields, who can bring valuable perspectives to the discipline. While interdisciplinary connections between biologists and engineers have built synthetic biology via the science and the technology of biology, interdisciplinary collaboration with artists, designers, and social theorists can provide insight on the connections between technology and society. Such collaborations can open up new avenues and new principles for research and design, as well as shed new light on the challenging context-dependence-both biological and social-that face living technologies at many scales. This review is inspired by the session titled "Design and Synthetic Biology: Connecting People and Technology" at Synthetic Biology 6.0 and covers a range of literature on design practice in synthetic biology and beyond. Critical engagement with how design is used to shape the discipline opens up new possibilities for how we might design the future of synthetic biology.

  4. Native listening: The flexibility dimension

    NARCIS (Netherlands)

    Cutler, A.

    2012-01-01

    The way we listen to spoken language is tailored to the specific benefit of native-language speech input. Listening to speech in non-native languages can be significantly hindered by this native bias. Is it possible to determine the degree to which a listener is listening in a native-like manner? Pr

  5. 3-D Synthetic Microstructure Generation with Ellipsoid Particles

    Science.gov (United States)

    2016-09-27

    oriented ellipses that have an 8:8:1 aspect ratio (i.e., plates ). Again, the 2-D image appears to contain a mix of particle sizes and shapes when in...Functions 23 Distribution List 26 iii Approved for public release; distribution is unlimited. List of Figures Fig. 1 2-D images of 3-D synthetic...4 Fig. 2 2-D images of 3-D periodic synthetic microstructure with uniform ellipses of 4:1:1 aspect ratio that are

  6. Super-Resolution for Synthetic Zooming

    Directory of Open Access Journals (Sweden)

    Li Xin

    2006-01-01

    Full Text Available Optical zooming is an important feature of imaging systems. In this paper, we investigate a low-cost signal processing alternative to optical zooming—synthetic zooming by super-resolution (SR techniques. Synthetic zooming is achieved by registering a sequence of low-resolution (LR images acquired at varying focal lengths and reconstructing the SR image at a larger focal length or increased spatial resolution. Under the assumptions of constant scene depth and zooming speed, we argue that the motion trajectories of all physical points are related to each other by a unique vanishing point and present a robust technique for estimating its D coordinate. Such a line-geometry-based registration is the foundation of SR for synthetic zooming. We address the issue of data inconsistency arising from the varying focal length of optical lens during the zooming process. To overcome the difficulty of data inconsistency, we propose a two-stage Delaunay-triangulation-based interpolation for fusing the LR image data. We also present a PDE-based nonlinear deblurring to accommodate the blindness and variation of sensor point spread functions. Simulation results with real-world images have verified the effectiveness of the proposed SR techniques for synthetic zooming.

  7. Images

    Data.gov (United States)

    National Aeronautics and Space Administration — Images for the website main pages and all configurations. The upload and access points for the other images are: Website Template RSW images BSCW Images HIRENASD...

  8. Structure-driven design of radionuclide tracers for non-invasive imaging of uPAR and targeted radiotherapy. The tale of a synthetic peptide antagonist

    DEFF Research Database (Denmark)

    Ploug, Michael

    2013-01-01

    as for monitoring the effects of such treatments by non-invasive imaging using e.g. positron emission tomography. This mini-review will focus on recent advancements in translational research devoted to non-invasive targeting of uPAR, with a view to molecular imaging of its expression in live individuals as well......-function relationships in uPAR has been refined to such a level that a rational design of uPAR function as well as compounds specifically targeting defined functions of uPAR are now realistic options. This knowledge opens new avenues for developing therapeutic intervention regimens targeting uPAR as well...... as specific eradication of these cells by targeted radiotherapy....

  9. A synthetic approach to multiobjective optimization

    CERN Document Server

    Lovison, Alberto

    2010-01-01

    We propose a strategy for approximating Pareto optimal sets based on the global analysis framework proposed by Smale (Dynamical systems, Academic Press, New York (1973) 531--544). We speak about \\emph{synthetic} approach because the optimal set is natively approximated by means of a compound geometrical object, i.e., a simplicial complex, rather than by an unstructured scatter of individual optima. The method distinguishes the hierarchy between singular set, Pareto critical set and stable Pareto critical set. Furthermore, a quadratic convergence result in set wise sense is proven and tested over numerical examples.

  10. Queueing-Based Synchronization and Entrainment for Synthetic Gene Oscillators

    Science.gov (United States)

    Mather, William; Butzin, Nicholas; Hochendoner, Philip; Ogle, Curtis

    Synthetic gene oscillators have been a major focus of synthetic biology research since the beginning of the field 15 years ago. They have proven to be useful both for biotechnological applications as well as a testing ground to significantly develop our understanding of the design principles behind synthetic and native gene oscillators. In particular, the principles governing synchronization and entrainment of biological oscillators have been explored using a synthetic biology approach. Our work combines experimental and theoretical approaches to specifically investigate how a bottleneck for protein degradation, which is present in most if not all existing synthetic oscillators, can be leveraged to robustly synchronize and entrain biological oscillators. We use both the terminology and mathematical tools of queueing theory to intuitively explain the role of this bottleneck in both synchronization and entrainment, which extends prior work demonstrating the usefulness of queueing theory in synthetic and native gene circuits. We conclude with an investigation of how synchronization and entrainment may be sensitive to the presence of multiple proteolytic pathways in a cell that couple weakly through crosstalk. This work was supported by NSF Grant #1330180.

  11. Immigrants and Native Workers

    DEFF Research Database (Denmark)

    Foged, Mette; Peri, Giovanni

    Using a database that includes the universe of individuals and establishments in Denmark over the period 1991-2008 we analyze the effect of a large inflow of non-European (EU) immigrants on Danish workers. We first identify a sharp and sustained supply-driven increase in the inflow of non......-EU immigrants in Denmark, beginning in 1995 and driven by a sequence of international events such as the Bosnian, Somalian and Iraqi crises. We then look at the response of occupational complexity, job upgrading and downgrading, wage and employment of natives in the short and long run. We find...... that the increased supply of non-EU low skilled immigrants pushed native workers to pursue more complex occupations. This reallocation happened mainly through movement across firms. Immigration increased mobility of natives across firms and across municipalities but it did not increase their probability...

  12. Engineering biofuel tolerance in non-native producing microorganisms.

    Science.gov (United States)

    Jin, Hu; Chen, Lei; Wang, Jiangxin; Zhang, Weiwen

    2014-01-01

    Large-scale production of renewable biofuels through microbiological processes has drawn significant attention in recent years, mostly due to the increasing concerns on the petroleum fuel shortages and the environmental consequences of the over-utilization of petroleum-based fuels. In addition to native biofuel-producing microbes that have been employed for biofuel production for decades, recent advances in metabolic engineering and synthetic biology have made it possible to produce biofuels in several non-native biofuel-producing microorganisms. Compared to native producers, these non-native systems carry the advantages of fast growth, simple nutrient requirements, readiness for genetic modifications, and even the capability to assimilate CO2 and solar energy, making them competitive alternative systems to further decrease the biofuel production cost. However, the tolerance of these non-native microorganisms to toxic biofuels is naturally low, which has restricted the potentials of their application for high-efficiency biofuel production. To address the issues, researches have been recently conducted to explore the biofuel tolerance mechanisms and to construct robust high-tolerance strains for non-native biofuel-producing microorganisms. In this review, we critically summarize the recent progress in this area, focusing on three popular non-native biofuel-producing systems, i.e. Escherichia coli, Lactobacillus and photosynthetic cyanobacteria.

  13. Synthetic cathinone abuse

    Directory of Open Access Journals (Sweden)

    Capriola M

    2013-07-01

    Full Text Available Michael Capriola Thomasville Medical Center, Thomasville, NC, USA Abstract: The abuse of synthetic cathinones, widely known as bath salts, has been increasing since the mid-2000s. These substances are derivatives of the naturally occurring compound cathinone, which is the primary psychoactive component of khat. The toxicity of synthetic cathinones includes significant sympathomimetic effects, as well as psychosis, agitation, aggression, and sometimes violent and bizarre behavior. Mephedrone and methylenedioxypyrovalerone are currently the predominantly abused synthetic cathinones. Keywords: designer drugs/chemistry, street drugs/pharmacology, substance-related disorders/epidemiology, alkaloids/poisoning

  14. Synthetic Base Fluids

    Science.gov (United States)

    Brown, M.; Fotheringham, J. D.; Hoyes, T. J.; Mortier, R. M.; Orszulik, S. T.; Randles, S. J.; Stroud, P. M.

    The chemical nature and technology of the main synthetic lubricant base fluids is described, covering polyalphaolefins, alkylated aromatics, gas-to-liquid (GTL) base fluids, polybutenes, aliphatic diesters, polyolesters, polyalkylene glycols or PAGs and phosphate esters.Other synthetic lubricant base oils such as the silicones, borate esters, perfluoroethers and polyphenylene ethers are considered to have restricted applications due to either high cost or performance limitations and are not considered here.Each of the main synthetic base fluids is described for their chemical and physical properties, manufacture and production, their chemistry, key properties, applications and their implications when used in the environment.

  15. Encrusted pyelitis of native kidneys.

    Science.gov (United States)

    Hertig, A; Duvic, C; Chretien, Y; Jungers, P; Grünfeld, J P; Rieu, P

    2000-06-01

    This study reports the first four cases of encrusted pyelitis involving native kidneys. The clinical features, management, and outcome of these patients were analyzed. Predisposing factors were underlying urologic disease and/or urologic manipulations, debilitating diseases, hospitalization, and prolonged antibiotic therapies. Presenting symptoms were renal failure in three patients with ureteroileal urinary diversion and manifestations of cystitis in one patient. Computed tomography scan of the urinary tract was critical for diagnosis. Presence of struvite was demonstrated by crystalluria and infrared spectrophotometry analysis of the encrusted material. Corynebacterium urealyticum urinary infection was identified in one case. Surgery (one patient) and palliative ureteral diversion (one patient), respectively, led to death and end-stage renal failure. Successful dissolution of encrusted pyelitis was obtained in two patients treated with intravenous vancomycin and local acidification of the renal collecting system. Clinical observation shows that encrusted pyelitis is a threatening disorder that destroys the native kidneys and may lead to end-stage renal failure. Successful treatment of the disease by chemolysis and antibiotics depends on correct and early diagnosis. Diagnosis required recognition of the predisposing factors, computed tomography imaging of the urinary tract, crystalluria, and identification of urea-splitting bacteria with prolonged culture on selective medium.

  16. Review of Ship Surveillance Technologies Based on High-Resolution Wide-Swath Synthetic Aperture Radar Imaging%HRWS SAR图像舰船目标监视技术研究综述

    Institute of Scientific and Technical Information of China (English)

    邢相薇; 计科峰; 康利鸿; 詹明

    2015-01-01

    合成孔径雷达(Synthetic Aperture Radar, SAR)是实现舰船目标监视应用的重要遥感手段之一。高分辨率宽测绘带(High Resolution Wide Swath, HRWS) SAR 能够同时获取方位向高分辨率和宽测绘带SAR数据,为SAR图像舰船目标监视带来了新的机遇和挑战。该文综述了国内外SAR图像舰船目标监视技术研究现状,总结了舰船监视对SAR成像系统基本性能要求,结合HRWS SAR成像特点,分析了舰船目标监视面临的关键技术问题,重点介绍了研究小组在HRWS SAR图像舰船目标检测、特征提取、分类识别等关键问题的解决方案和初步研究成果,并指出需进一步研究的方向。%Synthetic Aperture Radar (SAR) is widely used in ship surveillance. High-Resolution Wide-Swath (HRWS) SAR data are simultaneously collected, which introduces challenges and offers new research opportunities. SAR-based ship-surveillance technologies and the performance requirements of SAR systems are reviewed and summarized. Furthermore, the characteristics of HRWS SAR imaging and ship surveillance technologies are considered in tandem, and preliminary research results on ship detection, feature extraction, and classification are discussed. Finally, we point out issues to be addressed in future work.

  17. Shape analysis of synthetic diamond

    CERN Document Server

    Mullan, C

    1997-01-01

    Two-dimensional images of synthetic industrial diamond particles were obtained using a camera, framegrabber and PC-based image analysis software. Various methods for shape quantification were applied, including two-dimensional shape factors, Fourier series expansion of radius as a function of angle, boundary fractal analysis, polygonal harmonics, and comer counting methods. The shape parameter found to be the most relevant was axis ratio, defined as the ratio of the minor axis to the major axis of the ellipse with the same second moments of area as the particle. Axis ratio was used in an analysis of the sorting of synthetic diamonds on a vibrating table. A model was derived based on the probability that a particle of a given axis ratio would travel to a certain bin. The model described the sorting of bulk material accurately but it was found not to be applicable if the shape mix of the feed material changed dramatically. This was attributed to the fact that the particle-particle interference was not taken int...

  18. Analysis of Synthetic Polymers.

    Science.gov (United States)

    Smith, Charles G.; And Others

    1989-01-01

    Reviews techniques for the characterization and analysis of synthetic polymers, copolymers, and blends. Includes techniques for structure determination, separation, and quantitation of additives and residual monomers; determination of molecular weight; and the study of thermal properties including degradation mechanisms. (MVL)

  19. 种族主义思想的露骨表现——浅析莱辛“太空小说”中的土著人形象%The Obvious Representation of Racism——On the Natives-Images in Lessing’s “Space Fictions”

    Institute of Scientific and Technical Information of China (English)

    陶淑琴

    2012-01-01

    "Space Fictions" wrote by English famous writer Doris Lessing,describes a series of native-images.These natives’ values are different.The high-level natives are the descendants of cultured race and they suffered Degenerative Disease.The low-level natives are savage and uncultured race.The lowest-level natives have not future of development,they are the unpromising race.The disfigurations of natives show the writer’s colonialism.%"太空小说"是英国著名女作家多丽丝.莱辛最重要的文学创作之一,塑造了一系列的土著人形象。这些土著种族的价值也有高下之分,其中,高级土著是患了种族退化病的文明民族后裔,低级土著则是原始的、野蛮的、落后的生番,而更加没有价值的则是那些注定没有发展前途的种族。对土著的丑化处理,完全暴露了莱辛的种族主义思想和殖民主义思想。

  20. Is Nativism Sufficient?

    Science.gov (United States)

    Braine, Martin D. S.

    1994-01-01

    Provides a brief history of the empiricism-nativism issue, considering present-day intellectual roots of nativist and empiricist inclinations. A schema is proposed for explaining the ontogenetic origin of an innate attribute or principle relevant to language. An attempt is made to explain the origin of primitives as derived by learning. (Contains…

  1. Non-native seagrass

    NARCIS (Netherlands)

    van Tussenbroek, B.I.; van Katwijk, M.M.; Bouma, T.J.; van der Heide, T.; Govers, L.L.; Leuven, R.S.E.W.

    2016-01-01

    Seagrasses comprise 78 species and are rarely invasive. But the seagrass Halophila stipulacea, firstly recorded in the Caribbean in the year 2002, has spread quickly throughout the region. Previous works have described this species as invasive in the Caribbean, forming dense mats that exclude native

  2. Installation of soft X-ray array diagnostics and its application to tomography reconstruction using synthetic KSTAR X-ray images

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Seung Hun; Jang, Juhyeok; Hong, Joohwan; Jang, Siwon; Choe, Wonho, E-mail: wchoe@kaist.ac.kr [Department of Physics, Korea Advanced Institute of Science and Technology, Daejeon 305-701 (Korea, Republic of); Impurity and Edge Research Center, Daejeon 305-701 (Korea, Republic of); Pacella, D.; Romano, A.; Gabellieri, L. [Associazione Euratom-ENEA sulla Fusione, C.R. Frascati 00044 (Italy); Kim, Junghee [National Fusion Research Institute, Daejeon 305-806 (Korea, Republic of); Major of Nuclear Fusion and Plasma Science Department, Korea University of Science and Technology, Daejeon 305-350 (Korea, Republic of)

    2014-11-15

    Four-array system of soft X-ray diagnostics was installed on KSTAR tokamak. Each array has 32 viewing chords of two photo-diode array detectors with spatial resolution of 2 cm. To estimate signals from the soft X-ray radiation power, typical n{sub e}, T{sub e}, and argon impurity line radiation profiles in KSTAR are chosen. The photo-diodes were absolutely calibrated as a function of the incident photon energy in 2–40 keV range with a portable X-ray tube. Two-dimensional T{sub e} image properties by multi-energy method were simulated and visualized with six combinations of beryllium filter sets within the dynamic range of signal ratio.

  3. 多参考光合成孔径DMIPH术的细胞相位重构%Reconstruction of cell phase by multi-reference light synthetic aperture digital microsopic image plane holographic technology

    Institute of Scientific and Technical Information of China (English)

    巩文迪; 卢兆林; 刘佳毅

    2012-01-01

    Digital holographic microscopy (DHM) extracts the phase information directly instead of traditional optical microscopy, and records high frequency and low frequency information of an object more accurately. Based on DHM, cell phase was reconstructed by means of angular spectrum algorithm and least-squares unwrapping algorithm. Quantitative observation and effective measurement were earned out for living biological sample cells. The experiment results indicates that multi-reference light synthetic aperture digital microscopic image plane holography can be effectively applied to the amplitude and phase reconstruction of the microstructures of three-dimension objects, it can improve synthetic degree of system significantly in recording the object' s high frequency and low frequency information, and the diffraction limit resolution 12. 81p/mm can be obtained. The results show that super resolution imaging of digital holographic can be effectively implemented based on this system, and three-dimension topography information and accurate phase distribution of the microstructure cells can be obtained.%为了克服传统光学显微术无法直接提取相位信息的不足而能更准确记录物体高频和低频信息的合成,采用多参考光合成孔径数字显微像面全息系统,并结合角谱算法和最小二乘解包裹算法实现了细胞的相位重构.选取活体细胞组织等相位型生物进行作为实验样本,对其进行定量观察和有效测量.结果表明,多参考光合成孔径数字显微像面全息系统可以有效地应用于3维物体显微结构的振幅和相位重构,能显著地提高记录系统的高频和低频信息在全息图上的合成度,并实现超出系统的衍射极限12.81p/mm的分辨率.该系统可以有效地实现数字全息系统的超分辨率成像,从而获得细胞显微结构的3维形貌信息和准确的相位分布.

  4. Native Peoples-Native Homelands Climate Change Workshop: Lessons Learned

    Science.gov (United States)

    Maynard, N. G.

    2003-12-01

    The Native Peoples-Native Homelands Climate Change Workshop was held on October 28 through November 01, 1998, as part of a series of workshops being held around the U.S. to improve the understanding of the potential consequences of climate variability and change for the Nation. This workshop was specifically designed by Native Peoples to examine the impacts of climate change and extreme weather variability on Native Peoples and Native Homelands from an indigenous cultural and spiritual perspective and to develop recommendations as well as identify potential response actions. The workshop brought together interested Native Peoples, representatives of Tribal governments, traditional elders, Tribal leaders, natural resource managers, Tribal College faculty and students, and climate scientists from government agencies and universities. It is clear that Tribal colleges and universities play a unique and critical role in the success of these emerging partnerships for decision-making in addition to the important education function for both Native and non-Native communities such as serving as a culturally- appropriate vehicle for access, analysis, control, and protection of indigenous cultural and intellectual property. During the discussions between scientists and policy-makers from both Native and non-Native communities, a number of important lessons emerged which are key to building more effective partnerships between Native and non-Native communities for collaboration and decision-making for a more sustainable future. This talk summarizes the key issues, recommendations, and lessons learned during this workshop.

  5. Intelligibility of native and non-native Dutch Speech

    NARCIS (Netherlands)

    Wijngaarden, S.J. van

    2001-01-01

    The intelligibility of speech is known to be lower if the speaker is non-native instead of native for the given language. This study is aimed at quantifying the overall degradation due to limitations of non-native speakers of Dutch, specifically of Dutch-speaking Americans who have lived in the Neth

  6. Speech intelligibility of native and non-native speech

    NARCIS (Netherlands)

    Wijngaarden, S.J. van

    1999-01-01

    The intelligibility of speech is known to be lower if the talker is non-native instead of native for the given language. This study is aimed at quantifying the overall degradation due to acoustic-phonetic limitations of non-native talkers of Dutch, specifically of Dutch-speaking Americans who have l

  7. Generation of 3D synthetic breast tissue

    Science.gov (United States)

    Elangovan, Premkumar; Dance, David R.; Young, Kenneth C.; Wells, Kevin

    2016-03-01

    Virtual clinical trials are an emergent approach for the rapid evaluation and comparison of various breast imaging technologies and techniques using computer-based modeling tools. A fundamental requirement of this approach for mammography is the use of realistic looking breast anatomy in the studies to produce clinically relevant results. In this work, a biologically inspired approach has been used to simulate realistic synthetic breast phantom blocks for use in virtual clinical trials. A variety of high and low frequency features (including Cooper's ligaments, blood vessels and glandular tissue) have been extracted from clinical digital breast tomosynthesis images and used to simulate synthetic breast blocks. The appearance of the phantom blocks was validated by presenting a selection of simulated 2D and DBT images interleaved with real images to a team of experienced readers for rating using an ROC paradigm. The average areas under the curve for 2D and DBT images were 0.53+/-.04 and 0.55+/-.07 respectively; errors are the standard errors of the mean. The values indicate that the observers had difficulty in differentiating the real images from simulated images. The statistical properties of simulated images of the phantom blocks were evaluated by means of power spectrum analysis. The power spectrum curves for real and simulated images closely match and overlap indicating good agreement.

  8. Native Americans' Interest in Horticulture.

    Science.gov (United States)

    Meyer, Mary Hockenberry

    1999-01-01

    Focus groups arranged by local Native American Master Gardeners on two Minnesota reservations determined community interest in extension-horticulture programs. Topics of interest included food preservation and historical Native-American uses of plants. (SK)

  9. Native Prairie Adaptive Management (NPAM)

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — NPAM is a framework for guiding annual decisions about the management of Service‐owned native prairie parcels that are prone to invasions by non‐native grasses,...

  10. Stellwagen Bank National Marine Sanctuary - Synthetic Aperture Radar (SAR) Imagery

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — This geodatabase contains Synthetic Aperture Radar images (SAR), which consist of a fine resolution (12.5-50m), two-dimensional radar backscatter map of the...

  11. Detection of small, slow ground targets using Synthetic Aperture Radar

    Science.gov (United States)

    Chen, Curtis; Chapin, Elaine; Rosen, Paul

    2005-01-01

    Synthetic aperture radar (SAR) along-track interferometry (ATI) is a technique for sensing Earth-surface motion. The technique involves interferometrically combining data from two radar images acquired from phase centers separated along the platform flight track.

  12. PIV Measurements and Mechanisms of Adjacent Synthetic Jets Interactions

    Institute of Scientific and Technical Information of China (English)

    LUO Zhen-Bing; XIA Zhi-Xun

    2008-01-01

    Interactions of adjacent synthetic jet actuators with varying relative amplitude and the relative phase of driving voltage are measured using a particle image velocimetry(PIV).Varying relative amplitude or relative phase of driving voltage of the adjacent actuators vectors the direction of the ensuing merged jet of the adjacent synthetic jets.The vectoring mechanism of the adjacent vortex pairs,attract-impact causing deflection(AICD),is provided to explain why the merged jet is generally vectored to the side of the phase-leading synthetic jet or the synthetic jet with higher driving voltage.

  13. Calibration and Validation of a Detailed Architectural Canopy Model Reconstruction for the Simulation of Synthetic Hemispherical Images and Airborne LiDAR Data

    Directory of Open Access Journals (Sweden)

    Magnus Bremer

    2017-02-01

    Full Text Available Canopy density measures such as the Leaf Area Index (LAI have become standardized mapping products derived from airborne and terrestrial Light Detection And Ranging (aLiDAR and tLiDAR, respectively data. A specific application of LiDAR point clouds is their integration into radiative transfer models (RTM of varying complexity. Using, e.g., ray tracing, this allows flexible simulations of sub-canopy light condition and the simulation of various sensors such as virtual hemispherical images or waveform LiDAR on a virtual forest plot. However, the direct use of LiDAR data in RTMs shows some limitations in the handling of noise, the derivation of surface areas per LiDAR point and the discrimination of solid and porous canopy elements. In order to address these issues, a strategy upgrading tLiDAR and Digital Hemispherical Photographs (DHP into plausible 3D architectural canopy models is suggested. The presented reconstruction workflow creates an almost unbiased virtual 3D representation of branch and leaf surface distributions, minimizing systematic errors due to the object–sensor relationship. The models are calibrated and validated using DHPs. Using the 3D models for simulations, their capabilities for the description of leaf density distributions and the simulation of aLiDAR and DHP signatures are shown. At an experimental test site, the suitability of the models, in order to systematically simulate and evaluate aLiDAR based LAI predictions under various scan settings is proven. This strategy makes it possible to show the importance of laser point sampling density, but also the diversity of scan angles and their quantitative effect onto error margins.

  14. Multi-antenna synthetic aperture radar

    CERN Document Server

    Wang, Wen-Qin

    2013-01-01

    Synthetic aperture radar (SAR) is a well-known remote sensing technique, but conventional single-antenna SAR is inherently limited by the minimum antenna area constraint. Although there are still technical issues to overcome, multi-antenna SAR offers many benefits, from improved system gain to increased degrees-of-freedom and system flexibility. Multi-Antenna Synthetic Aperture Radar explores the potential and challenges of using multi-antenna SAR in microwave remote sensing applications. These applications include high-resolution imaging, wide-swath remote sensing, ground moving target indica

  15. The Synthetic Cannabinoids Phenomenon.

    Science.gov (United States)

    Karila, Laurent; Benyamina, Amine; Blecha, Lisa; Cottencin, Olivier; Billieux, Joël

    2016-01-01

    « Spice » is generally used to describe the diverse types of herbal blends that encompass synthetic cannabinoids on the market. The emergence of smokable herbal products containing synthetic cannabinoids, which mimic the effects of cannabis, appears to become increasingly popular, in the new psychoactive substances landscape. In 2014, the existence of 134 different types of synthetic cannabinoids were reported by the European Union Early Warning System. These drugs are mainly sold online as an alternative to controlled and regulated psychoactive substances. They appear to have a life cycle of about 1-2 years before being replaced by a next wave of products. Legislation controlling these designer drugs has been introduced in many countries with the objective to limit the spread of existing drugs and control potential new analogs. The majority of the synthetic cannabinoids are full agonists at the CB1 receptor and do not contain tobacco or cannabis. They are becoming increasingly popular in adolescents, students and clubbers as an abused substance. Relatively high incidence of adverse effects associated with synthetic cannabinoids use has been documented in the literature. Numerous fatalities linked with their use and abuse have been reported. In this paper, we will review the available data regarding the use and effects of synthetic cannabinoids in humans in order to highlight their impact on public health. To reach this objective, a literature search was performed on two representative databases (Pubmed, Google Scholar), the Erowid Center website (a US non-profit educational organization that provides information about psychoactive plants and chemicals), and various governmental websites. The terms used for the database search were: "synthetic cannabinoids", "spice", "new psychoactive substances", and/or "substance use disorder", and/or "adverse effects", and/or "fatalities". The search was limited to years 2005 to 2016 due to emerging scientific literature at

  16. Who Stole Native American Studies?

    Science.gov (United States)

    Cook-Lynn, Elizabeth

    1997-01-01

    Native American Studies has failed to develop into an academic discipline because of the continued influence of postcolonial theories, attempts to discredit Native American scholars, politically determined research agendas, and the ideology of the "New Historicism." Native American Studies must seek autonomy from other opportunistic…

  17. Who Stole Native American Studies?

    Science.gov (United States)

    Cook-Lynn, Elizabeth

    1997-01-01

    Native American Studies has failed to develop into an academic discipline because of the continued influence of postcolonial theories, attempts to discredit Native American scholars, politically determined research agendas, and the ideology of the "New Historicism." Native American Studies must seek autonomy from other opportunistic…

  18. Digital Natives or Digital Tribes?

    Science.gov (United States)

    Watson, Ian Robert

    2013-01-01

    This research builds upon the discourse surrounding digital natives. A literature review into the digital native phenomena was undertaken and found that researchers are beginning to identify the digital native as not one cohesive group but of individuals influenced by other factors. Primary research by means of questionnaire survey of technologies…

  19. Assessment of bone synthetic activity in inflammatory lesions and syndesmophytes in patients with ankylosing spondylitis: the potential role of 18F-fluoride positron emission tomography-magnetic resonance imaging.

    Science.gov (United States)

    Lee, Seung-Geun; Kim, In-Joo; Kim, Keun-Young; Kim, Hee-Young; Park, Kyoung-June; Kim, Seong-Jang; Park, Eun-Kyoung; Jeon, Yun-Kyung; Yang, Byeong-Yun; Kim, Geun-Tae

    2015-01-01

    18F-fluoride uptake represents active osteoblastic bone synthesis. We assessed bone synthetic activity in inflammatory lesions and syndesmophytes in patients with ankylosing spondylitis (AS) using 18F-fluoride positron emission tomography-magnetic resonance imaging (PET-MRI, Philips Healthcare, Cleveland, OH, USA) and x-ray. All images of 12 AS patients were recorded with the presence or absence of increased 18F-fluoride uptake lesions on PET, acute (type A) or advanced (type B) corner inflammatory lesions (CILs) on MRI, syndesmophytes on x-ray at the anterior vertebral corners. An increased 18F-fluoride uptake lesion was defined as an uptake which is greater than the uptake in the adjacent normal vertebral body. The association of a CIL or syndesmophyte with an increased 18F-fluoride uptake lesion was investigated by generalised linear latent mixed models analysis to adjust within-patient dependence for total numbers of vertebral corners. There were 67 type A CILs (12.1%), 37 type B CILs (6.7%) and 58 increased 18F-fluoride uptake lesion (10.4%) out of 552 vertebral corners and there were 57 syndesmophytes (19.8%) out of 288 vertebral corners. A type A CIL (OR=3.2, 95% CI=1.6-6.5, p=0.001), type B CIL (OR=59.9, 95% CI=23.5-151.5, p<0.001) and syndesmpophyte (OR=21.8, 95% CI=5.5-85.2, p<0.001) were significantly associated with an increased 18F-fluoride uptake lesion. Our data suggest that an inflammatory lesion as well as a syndesmophyte is associated with active bone synthesis assessed by 18F-fluoride uptake in the spine of AS patients. 18F-fluoride PET-MRI may have the potential for investigating the pathogenesis of structural damage in AS.

  20. Synthetic guide star generation

    Science.gov (United States)

    Payne, Stephen A [Castro Valley, CA; Page, Ralph H [Castro Valley, CA; Ebbers, Christopher A [Livermore, CA; Beach, Raymond J [Livermore, CA

    2008-06-10

    A system for assisting in observing a celestial object and providing synthetic guide star generation. A lasing system provides radiation at a frequency at or near 938 nm and radiation at a frequency at or near 1583 nm. The lasing system includes a fiber laser operating between 880 nm and 960 nm and a fiber laser operating between 1524 nm and 1650 nm. A frequency-conversion system mixes the radiation and generates light at a frequency at or near 589 nm. A system directs the light at a frequency at or near 589 nm toward the celestial object and provides synthetic guide star generation.

  1. Asthma and American Indians/Alaska Natives

    Science.gov (United States)

    ... Minority Population Profiles > American Indian/Alaska Native > Asthma Asthma and American Indians/Alaska Natives In 2014, 218, ... Native American adults reported that they currently have asthma. American Indian/Alaska Native children are 30% more ...

  2. Stroke and Native Hawaiians/Pacific Islanders

    Science.gov (United States)

    ... Population Profiles > Native Hawaiian/Other Pacific Islander > Stroke Stroke and Native Hawaiians/Pacific Islanders Native Hawaiians/Pacific ... non-Hispanic white adults to die from a stroke in 2010. In general, Native Hawaiian/Pacific Islander ...

  3. 联合运动补偿的逆合成孔径雷达成像方位定标方法%Joint method of motion compensation and cross-range scajing for inverse synthetic aperture radar imaging

    Institute of Scientific and Technical Information of China (English)

    盛佳恋; 张磊; 邢孟道; 徐刚; 贺丽

    2014-01-01

    在雷达识别系统中,确定目标的尺寸对于提高目标识别能力具有重要的意义。针对逆合成孔径雷达(inverse synthetic aperture radar,ISAR)成像的定标问题,考虑了等效转台和残余平动引入的相位误差,提出了一种 ISAR 目标有效转动速度估计的新方法。通过在距离多普勒图像中自适应提取若干目标特征点,对其建立时变自回归模型(time-varying autoregressive,TVAR)。利用多项式拟合极点的多普勒历程,解算有效转动速度与残余相位误差系数。该方法不仅能可靠实现方位定标,残余的相位误差补偿可进一步提高图像的聚焦性能。仿真和实测数据实验验证了所提方法的有效性。%In radar target recognition systems,it is of great significance to determine the target size for im-proving the capability of identification.Considering the phase error induced by the equivalent turntable and re-sidual translation,this paper proposes a new method to estimate effective rotation velocity for inverse synthetic aperture radar (ISAR)cross-range scaling.By extracting some featured scatterers in the range-Doppler image,a time-varying autoregressive (TVAR)model is invoked for the scatterers.After polyfitting the Doppler histories of the poles,effective rotation velocity and residual phase error can be calculated.One contribution of this method lies in that it can reliably implement cross-range scaling.Simultaneously,the motion compensation processing can further improve the target focus.Simulation and real-data experiments verify the effectiveness of this proposal.

  4. Biodegradable synthetic bone composites

    Science.gov (United States)

    Liu, Gao; Zhao, Dacheng; Saiz, Eduardo; Tomsia, Antoni P.

    2013-01-01

    The invention provides for a biodegradable synthetic bone composition comprising a biodegradable hydrogel polymer scaffold comprising a plurality of hydrolytically unstable linkages, and an inorganic component; such as a biodegradable poly(hydroxyethylmethacrylate)/hydroxyapatite (pHEMA/HA) hydrogel composite possessing mineral content approximately that of human bone.

  5. Synthetic growth reference charts

    NARCIS (Netherlands)

    Hermanussen, Michael; Stec, Karol; Aßmann, Christian; Meigen, Christof; Van Buuren, Stef

    2016-01-01

    Objectives: To reanalyze the between-population variance in height, weight, and body mass index (BMI), and to provide a globally applicable technique for generating synthetic growth reference charts. Methods: Using a baseline set of 196 female and 197 male growth studies published since 1831, common

  6. Synthetic studies towards bottromycin

    Directory of Open Access Journals (Sweden)

    Stefanie Ackermann

    2012-10-01

    Full Text Available Thio-Ugi reactions are described as an excellent synthetic tool for the synthesis of sterically highly hindered endothiopeptides. S-Methylation and subsequent amidine formation can be carried out in an inter- as well as in an intramolecular fashion. The intramolecular approach allows the synthesis of the bottromycin ring system in a straightforward manner.

  7. Synthetic Plant Defense Elicitors

    Directory of Open Access Journals (Sweden)

    Yasemin eBektas

    2015-01-01

    Full Text Available To defend themselves against invading pathogens plants utilize a complex regulatory network that coordinates extensive transcriptional and metabolic reprogramming. Although many of the key players of this immunity-associated network are known, the details of its topology and dynamics are still poorly understood. As an alternative to forward and reverse genetic studies, chemical genetics-related approaches based on bioactive small molecules have gained substantial popularity in the analysis of biological pathways and networks. Use of such molecular probes can allow researchers to access biological space that was previously inaccessible to genetic analyses due to gene redundancy or lethality of mutations. Synthetic elicitors are small drug like molecules that induce plant defense responses, but are distinct from known natural elicitors of plant immunity. While the discovery of the some synthetic elicitors had already been reported in the 1970s, recent breakthroughs in combinatorial chemical synthesis now allow for inexpensive high-throughput screens for bioactive plant defense-inducing compounds. Along with powerful reverse genetics tools and resources available for model plants and crop systems, comprehensive collections of new synthetic elicitors will likely allow plant scientists to study the intricacies of plant defense signaling pathways and networks in an unparalleled fashion. As synthetic elicitors can protect crops from diseases, without the need to be directly toxic for pathogenic organisms, they may also serve as promising alternatives to conventional biocidal pesticides, which often are harmful for the environment, farmers and consumers. Here we are discussing various types of synthetic elicitors that have been used for studies on the plant immune system, their modes-of-action as well as their application in crop protection.

  8. Synthetic River Valleys

    Science.gov (United States)

    Brown, R.; Pasternack, G. B.

    2011-12-01

    The description of fluvial form has evolved from anecdotal descriptions to artistic renderings to 2D plots of cross section or longitudinal profiles and more recently 3D digital models. Synthetic river valleys, artificial 3D topographic models of river topography, have a plethora of potential applications in fluvial geomorphology, and the earth sciences in general, as well as in computer science and ecology. Synthetic river channels have existed implicitly since approximately the 1970s and can be simulated from a variety of approaches spanning the artistic and numerical. An objective method of synthesizing 3D stream topography based on reach scale attributes would be valuable for sizing 3D flumes in the physical and numerical realms, as initial input topography for morphodynamic models, stream restoration design, historical reconstruction, and mechanistic testing of interactions of channel geometric elements. Quite simply - simulation of synthetic channel geometry of prescribed conditions can allow systematic evaluation of the dominant relationships between river flow and geometry. A new model, the control curve method, is presented that uses hierarchically scaled parametric curves in over-lapping 2D planes to create synthetic river valleys. The approach is able to simulate 3D stream geometry from paired 2D descriptions and can allow experimental insight into form-process relationships in addition to visualizing past measurements of channel form that are limited to two dimension descriptions. Results are presented that illustrate the models ability to simulate fluvial topography representative of real world rivers as well as how channel geometric elements can be adjusted. The testing of synthetic river valleys would open up a wealth of knowledge as to why some 3D attributes of river channels are more prevalent than others as well as bridging the gap between the 2D descriptions that have dominated fluvial geomorphology the past century and modern, more complete, 3D

  9. New Precision Guidance Method Based on Bistatic Synthetic Apterture Radar

    Institute of Scientific and Technical Information of China (English)

    YANG Chun; ZENG Tao

    2008-01-01

    A new method is presented to improve guidance precision.This method is based on histatic synthetic aperture radar.The illuminator works in side looking mode,providing the synthetic aperture and the receiver is disposed on the seeker which operates in the forward looking mode.The receiving antenna is composed of four sub-antennas and so four synthetic aperture radar(SAR)images are to be generated.Target is positioned in SAR images by image matching.The bearing and elevation of image element of target are measured by the principle of monopulse angular measurement.Theory of the proposed method is derived and simulation on bearing measurement is done.Simulation shows that the method is valid and if SNR of target's image is above 30 dB.the angular measuring difference is witbin the confines of 0.04 degree.

  10. Space Radar Image of Central Sumatra, Indonesia

    Science.gov (United States)

    1994-01-01

    This is a radar image of the central part of the island of Sumatra in Indonesia that shows how the tropical rainforest typical of this country is being impacted by human activity. Native forest appears in green in this image, while prominent pink areas represent places where the native forest has been cleared. The large rectangular areas have been cleared for palm oil plantations. The bright pink zones are areas that have been cleared since 1989, while the dark pink zones are areas that were cleared before 1989. These radar data were processed as part of an effort to assist oil and gas companies working in the area to assess the environmental impact of both their drilling operations and the activities of the local population. Radar images are useful in these areas because heavy cloud cover and the persistent smoke and haze associated with deforestation have prevented usable visible-light imagery from being acquired since 1989. The dark shapes in the upper right (northeast) corner of the image are a chain of lakes in flat coastal marshes. This image was acquired in October 1994 by the Spaceborne Imaging Radar C/X-Band Synthetic Aperture Radar (SIR-C/X-SAR) onboard the space shuttle Endeavour. Environmental changes can be easily documented by comparing this image with visible-light data that were acquired in previous years by the Landsat satellite. The image is centered at 0.9 degrees north latitude and 101.3 degrees east longitude. The area shown is 50 kilometers by 100 kilometers (31 miles by 62 miles). The colors in the image are assigned to different frequencies and polarizations of the radar as follows: red is L-band horizontally transmitted, horizontally received; green is L-band horizontally transmitted, vertically received; blue is L-band vertically transmitted, vertically received. SIR-C/X-SAR, a joint mission of the German, Italian and United States space agencies, is part of NASA's Mission to Planet Earth program.

  11. Space Radar Image of Central Sumatra, Indonesia

    Science.gov (United States)

    1994-01-01

    This is a radar image of the central part of the island of Sumatra in Indonesia that shows how the tropical rainforest typical of this country is being impacted by human activity. Native forest appears in green in this image, while prominent pink areas represent places where the native forest has been cleared. The large rectangular areas have been cleared for palm oil plantations. The bright pink zones are areas that have been cleared since 1989, while the dark pink zones are areas that were cleared before 1989. These radar data were processed as part of an effort to assist oil and gas companies working in the area to assess the environmental impact of both their drilling operations and the activities of the local population. Radar images are useful in these areas because heavy cloud cover and the persistent smoke and haze associated with deforestation have prevented usable visible-light imagery from being acquired since 1989. The dark shapes in the upper right (northeast) corner of the image are a chain of lakes in flat coastal marshes. This image was acquired in October 1994 by the Spaceborne Imaging Radar C/X-Band Synthetic Aperture Radar (SIR-C/X-SAR) onboard the space shuttle Endeavour. Environmental changes can be easily documented by comparing this image with visible-light data that were acquired in previous years by the Landsat satellite. The image is centered at 0.9 degrees north latitude and 101.3 degrees east longitude. The area shown is 50 kilometers by 100 kilometers (31 miles by 62 miles). The colors in the image are assigned to different frequencies and polarizations of the radar as follows: red is L-band horizontally transmitted, horizontally received; green is L-band horizontally transmitted, vertically received; blue is L-band vertically transmitted, vertically received. SIR-C/X-SAR, a joint mission of the German, Italian and United States space agencies, is part of NASA's Mission to Planet Earth program.

  12. Aquatic macroinvertebrate responses to native and non-native predators

    Directory of Open Access Journals (Sweden)

    Haddaway N. R.

    2014-01-01

    Full Text Available Non-native species can profoundly affect native ecosystems through trophic interactions with native species. Native prey may respond differently to non-native versus native predators since they lack prior experience. Here we investigate antipredator responses of two common freshwater macroinvertebrates, Gammarus pulex and Potamopyrgus jenkinsi, to olfactory cues from three predators; sympatric native fish (Gasterosteus aculeatus, sympatric native crayfish (Austropotamobius pallipes, and novel invasive crayfish (Pacifastacus leniusculus. G. pulex responded differently to fish and crayfish; showing enhanced locomotion in response to fish, but a preference for the dark over the light in response to the crayfish. P.jenkinsi showed increased vertical migration in response to all three predator cues relative to controls. These different responses to fish and crayfish are hypothesised to reflect the predators’ differing predation types; benthic for crayfish and pelagic for fish. However, we found no difference in response to native versus invasive crayfish, indicating that prey naiveté is unlikely to drive the impacts of invasive crayfish. The Predator Recognition Continuum Hypothesis proposes that benefits of generalisable predator recognition outweigh costs when predators are diverse. Generalised responses of prey as observed here will be adaptive in the presence of an invader, and may reduce novel predators’ potential impacts.

  13. Generating and analyzing synthetic finger vein images

    NARCIS (Netherlands)

    Hillerström, Fieke; Kumar, Ajay; Veldhuis, Raymond

    2014-01-01

    Abstract: The finger-vein biometric offers higher degree of security, personal privacy and strong anti-spoofing capabilities than most other biometric modalities employed today. Emerging privacy concerns with the database acquisition and lack of availability of large scale finger-vein database have

  14. Biomedically relevant circuit-design strategies in mammalian synthetic biology.

    Science.gov (United States)

    Bacchus, William; Aubel, Dominique; Fussenegger, Martin

    2013-01-01

    The development and progress in synthetic biology has been remarkable. Although still in its infancy, synthetic biology has achieved much during the past decade. Improvements in genetic circuit design have increased the potential for clinical applicability of synthetic biology research. What began as simple transcriptional gene switches has rapidly developed into a variety of complex regulatory circuits based on the transcriptional, translational and post-translational regulation. Instead of compounds with potential pharmacologic side effects, the inducer molecules now used are metabolites of the human body and even members of native cell signaling pathways. In this review, we address recent progress in mammalian synthetic biology circuit design and focus on how novel designs push synthetic biology toward clinical implementation. Groundbreaking research on the implementation of optogenetics and intercellular communications is addressed, as particularly optogenetics provides unprecedented opportunities for clinical application. Along with an increase in synthetic network complexity, multicellular systems are now being used to provide a platform for next-generation circuit design.

  15. Traditional West Coast Native Medicine

    OpenAIRE

    Deagle, George

    1988-01-01

    An important part of the complex culture of the Native people of Canada's Pacific coast is the traditional system of medicine each culture has developed. Population loss from epidemics and the influence of dominant European cultures has resulted in loss of many aspects of traditional medicine. Although some Native practices are potentially hazardous, continuation of traditional approaches to illness remains an important part of health care for many Native people. The use of “devil's club” pla...

  16. These Synthetic Times

    Institute of Scientific and Technical Information of China (English)

    KIT GILLET

    2008-01-01

    @@ Already slated to be one of the most important cultural events in the buildup to this summer's Olympic games, Synthetic Times-Media Art China 2008 will feature the works of more than 30 artists from around the world. Upwards of 40 media art installations will be exhibited in the National Art Museum of China alone, along with performances, workshops, presentations, and discussion panels focusing on the art works and the growth of media art as a discipline.

  17. Synthetic gases production

    Energy Technology Data Exchange (ETDEWEB)

    Mazaud, J.P.

    1996-06-01

    The natural gas or naphtha are the main constituents used for the production of synthetic gases. Several production ways of synthetic gases are industrially used as for example the natural gas or naphtha catalytic reforming, the selective oxidation of natural gas or heavy fuels and the coal oxy-vapo-gasification. The aim of this work is to study the different steps of production and treatment of the synthetic gases by the way of catalytic reforming. The first step is the desulfurization of the hydrocarbons feedstocks. The process used in industry is described. Then is realized the catalytic hydrocarbons reforming process. After having recalled some historical data on the catalytic reforming, the author gives the reaction kinetics and thermodynamics. The possible reforming catalysts, industrial equipments and furnaces designs are then exposed. The carbon dioxide is a compound easily obtained during the reforming reactions. It is a wasteful and harmful component which has to be extracted of the gaseous stream. The last step is then the gases de-carbonation. Two examples of natural gas or naphtha reforming reactions are at last given: the carbon monoxide conversion by steam and the carbon oxides reactions with hydrogen (methanization). (O.M.). 8 figs., 6 tabs.

  18. Synthetic biology in plastids.

    Science.gov (United States)

    Scharff, Lars B; Bock, Ralph

    2014-06-01

    Plastids (chloroplasts) harbor a small gene-dense genome that is amenable to genetic manipulation by transformation. During 1 billion years of evolution from the cyanobacterial endosymbiont to present-day chloroplasts, the plastid genome has undergone a dramatic size reduction, mainly as a result of gene losses and the large-scale transfer of genes to the nuclear genome. Thus the plastid genome can be regarded as a naturally evolved miniature genome, the gradual size reduction and compaction of which has provided a blueprint for the design of minimum genomes. Furthermore, because of the largely prokaryotic genome structure and gene expression machinery, the high transgene expression levels attainable in transgenic chloroplasts and the very low production costs in plant systems, the chloroplast lends itself to synthetic biology applications that are directed towards the efficient synthesis of green chemicals, biopharmaceuticals and other metabolites of commercial interest. This review describes recent progress with the engineering of plastid genomes with large constructs of foreign or synthetic DNA, and highlights the potential of the chloroplast as a model system in bottom-up and top-down synthetic biology approaches.

  19. Native Speakers' Perception of Non-Native English Speech

    Science.gov (United States)

    Jaber, Maysa; Hussein, Riyad F.

    2011-01-01

    This study is aimed at investigating the rating and intelligibility of different non-native varieties of English, namely French English, Japanese English and Jordanian English by native English speakers and their attitudes towards these foreign accents. To achieve the goals of this study, the researchers used a web-based questionnaire which…

  20. Comparison of quiescent inflow single-shot and native space for nonenhanced peripheral MR angiography.

    Science.gov (United States)

    Ward, Emily V; Galizia, Mauricio S; Usman, Asad; Popescu, Andrada R; Dunkle, Eugene; Edelman, Robert R

    2013-12-01

    To evaluate two nonenhanced MRA methods: quiescent-interval single-shot (QISS) and Native SPACE (NATIVE = Non-contrast Angiography of the Arteries and Veins; SPACE = Sampling Perfection with Application Optimized Contrast by using different flip angle Evolution), using contrast-enhanced MR angiography (CEMRA) as a reference standard. Twenty patients (14 male; mean, 69.3 years old) referred for lower extremity MRA were recruited in a HIPAA-compliant prospective study. QISS and Native SPACE of the lower extremities were performed at 1.5 Tesla with a hybrid dual-injection contrast-enhanced MRA as reference. Image quality and stenosis severity were assessed in segments by two blinded radiologists. Methods were compared with logistic regression for correlated data for diagnostic accuracy. Of 496 arterial segments, 24 were considered nondiagnostic on the Native SPACE images. There were no QISS or CEMRA imaging segments considered to be nondiagnostic. Image quality was significantly higher for QISS than for Native SPACE. QISS stenosis sensitivity (84.9%) was not significantly different from Native SPACE (87.3%). QISS had better specificity (95.6%) than Native SPACE (87.0%), P = 0.0041. In comparison with QISS, Native SPACE proved less robust for imaging of the abdominal and pelvic segments. Native SPACE and QISS were sensitive for hemodynamically significant stenosis in this pilot study. QISS NEMRA demonstrated superior specificity and image quality, and was more robust in the abdominal and pelvic regions. Copyright © 2013 Wiley Periodicals, Inc.

  1. Opportunities in plant synthetic biology.

    Science.gov (United States)

    Cook, Charis; Martin, Lisa; Bastow, Ruth

    2014-05-01

    Synthetic biology is an emerging field uniting scientists from all disciplines with the aim of designing or re-designing biological processes. Initially, synthetic biology breakthroughs came from microbiology, chemistry, physics, computer science, materials science, mathematics, and engineering disciplines. A transition to multicellular systems is the next logical step for synthetic biologists and plants will provide an ideal platform for this new phase of research. This meeting report highlights some of the exciting plant synthetic biology projects, and tools and resources, presented and discussed at the 2013 GARNet workshop on plant synthetic biology.

  2. Synthetic cannabis and respiratory depression.

    Science.gov (United States)

    Jinwala, Felecia N; Gupta, Mayank

    2012-12-01

    In recent years, synthetic cannabis use has been increasing in appeal among adolescents, and its use is now at a 30 year peak among high school seniors. The constituents of synthetic cannabis are difficult to monitor, given the drug's easy accessibility. Currently, 40 U.S. states have banned the distribution and use of some known synthetic cannabinoids, and have included these drugs in the Schedule I category. The depressive respiratory effect in humans caused by synthetic cannabis inhalation has not been thoroughly investigated in the medical literature. We are the first to report, to our knowledge, two cases of self-reported synthetic cannabis use leading to respiratory depression and necessary intubation.

  3. Native American youth and justice

    Directory of Open Access Journals (Sweden)

    Dr.Sc. Laurence A. French

    2012-12-01

    Full Text Available Youth and delinquency issues have long been problematic among Native Americans groups both on- and off-reservation. This phenomenon is further complicated by the cultural diversity among American Indians and Alaska Natives scattered across the United States. In address these issues, the paper begins with a historical overview of Native American youth. This history presents the long tradition of federal policies that, how well intended, have resulted in discriminatory practices with the most damages attacks being those directed toward the destruction of viable cultural attributes – the same attributes that make Native Americans unique within United States society. Following the historical material, the authors contrast the pervasive Native American aboriginal ethos of harmony with that of Protestant Ethic that dominates the ethos of the larger United States society. In addition to providing general information on Native American crime and delinquency, the paper also provides a case study of Native American justice within the Navajo Nation, the largest tribe, in both size and population, in the United States. The paper concludes with a discussion of issues specific to Native American youth and efforts to address these problems.

  4. Native American Foods and Cookery.

    Science.gov (United States)

    Taylor, Tom; Potter, Eloise F.

    Native Americans had a well-developed agriculture long before the arrival of the Europeans. Three staples--corn, beans, and squash--were supplemented with other gathered plants or cultivated crops such as white potatoes, sweet potatoes, pumpkins, and peanuts. Native Americans had no cows, pigs, or domesticated chickens; they depended almost…

  5. Ohiyesa's Path: Reclaiming Native Education

    Science.gov (United States)

    James, Adrienne Brant; Renville, Tammy

    2012-01-01

    As Natives have assumed increasing authority and responsibility for tribal and federally funded and administered schools, a more balanced and enlightened view is emerging. Notable among these events is the recognition of the critical need to shift emphasis to the untapped heritage of more recently recognized and acknowledged Native American…

  6. Coyote's Eyes: Native Cognition Styles.

    Science.gov (United States)

    Tafoya, Terry

    1982-01-01

    Using a Native American parable, compares the Standard Average European (SAE) world view with the Standard Native American (SNA) world view and the effects they have on education. Points out possible areas of interethnic confusion as a result of these two world views in communication dealing with cognitive schemes. (LC)

  7. Native American Foods and Cookery.

    Science.gov (United States)

    Taylor, Tom; Potter, Eloise F.

    Native Americans had a well-developed agriculture long before the arrival of the Europeans. Three staples--corn, beans, and squash--were supplemented with other gathered plants or cultivated crops such as white potatoes, sweet potatoes, pumpkins, and peanuts. Native Americans had no cows, pigs, or domesticated chickens; they depended almost…

  8. Bistatic synthetic aperture radar using two satellites

    Science.gov (United States)

    Tomiyasu, K.

    1978-01-01

    The paper demonstrates the feasibility of a bistatic synthetic aperture radar (BISAR) utilizing two satellites. The proposed BISAR assumes that the direction of the two narrow antenna beams are programmed to coincide over the desired area to be imaged. Functionally, the transmitter and receiver portions can be interchanged between the two satellites. The two satellites may be in one orbit plane or two different orbits such as geosynchronous and low-earth orbits. The pulse repetition frequency and imaging geometry are constrained by contours of isodops and isodels. With two images of the same area viewed from different angles, it is possible in principle to derive three-dimensional stereo images. Applications of BISAR include topography, water resource management, and soil moisture determination.. Advantages of BISAR over a monostatic SAR are mentioned, including lower transmitter power and greater ranges in incidence angle and coverage.

  9. Biopolymers Versus Synthetic Polymers

    Directory of Open Access Journals (Sweden)

    Florentina Adriana Cziple

    2008-10-01

    Full Text Available This paper present an overview of important synthetic and natural polymers with emphasis on polymer structure, the chemistry of polymer formation. an introduction to polymer characterization. The biodegradation process can take place aerobically and anaerobically with or without the presence of light. These factors allow for biodegradation even in landfill conditions which are normally inconducive to any degradation. The sheeting used to make these packages differs significantly from other “degradable plastics” in the market as it does not attempt to replace the current popular materials but instead enhances them by rendering them biodegradable.

  10. CASH vs. SYNTHETIC CDOs

    Directory of Open Access Journals (Sweden)

    Silviu Eduard Dinca

    2015-12-01

    Full Text Available During the past few years, in the recent post-crisis aftermath, global asset managers are constantly searching new ways to optimize their investment portfolios while financial and banking institutions around the world are exploring new alternatives to better secure their financing and refinancing demands altogether with the enhancement of their risk management capabilities. We will exhibit herewith a comparison between the true-sale and synthetic CDO securitizations as financial markets-based funding, investment and risks mitigation techniques, highlighting certain key structuring and implementation specifics on each of them.

  11. Playing God? Synthetic biology as a theological and ethical challenge

    OpenAIRE

    2009-01-01

    In the ethical debate over synthetic biology the formula “playing god” is widely used in order to attack this new branch of biotechnology. The article analyses, contextualizes and criticises this usage with respect to the theological concepts of creation, sin and humans as created in the image of God. Against the background of these theological understandings an ethical corridor of how to responsibly cope with the societal challenges of synthetic biology is presented.

  12. Playing God? Synthetic biology as a theological and ethical challenge.

    Science.gov (United States)

    Dabrock, Peter

    2009-12-01

    In the ethical debate over synthetic biology the formula "playing god" is widely used in order to attack this new branch of biotechnology. The article analyses, contextualizes and criticises this usage with respect to the theological concepts of creation, sin and humans as created in the image of God. Against the background of these theological understandings an ethical corridor of how to responsibly cope with the societal challenges of synthetic biology is presented.

  13. Functional differences between native and alien species: a global-scale comparison

    DEFF Research Database (Denmark)

    Ordonez Gloria, Alejandro

    2010-01-01

    1. A prevalent question in the study of plant invasions has been whether or not invasions can be explained on the basis of traits. Despite many attempts, a synthetic view of multi-trait differences between alien and native species is not yet available.2. We compiled a database of three ecologically...

  14. Functional differences between native and alien species : a global-scale comparison

    NARCIS (Netherlands)

    Ordonez, Alejandro; Wright, Ian J.; Olff, Han; Kitajima, Kaoru

    2010-01-01

    1. A prevalent question in the study of plant invasions has been whether or not invasions can be explained on the basis of traits. Despite many attempts, a synthetic view of multi-trait differences between alien and native species is not yet available. 2. We compiled a database of three ecologically

  15. Synthetic collective intelligence.

    Science.gov (United States)

    Solé, Ricard; Amor, Daniel R; Duran-Nebreda, Salva; Conde-Pueyo, Núria; Carbonell-Ballestero, Max; Montañez, Raúl

    2016-10-01

    Intelligent systems have emerged in our biosphere in different contexts and achieving different levels of complexity. The requirement of communication in a social context has been in all cases a determinant. The human brain, probably co-evolving with language, is an exceedingly successful example. Similarly, social insects complex collective decisions emerge from information exchanges between many agents. The difference is that such processing is obtained out of a limited individual cognitive power. Computational models and embodied versions using non-living systems, particularly involving robot swarms, have been used to explore the potentiality of collective intelligence. Here we suggest a novel approach to the problem grounded in the genetic engineering of unicellular systems, which can be modified in order to interact, store memories or adapt to external stimuli in collective ways. What we label as Synthetic Swarm Intelligence defines a parallel approach to the evolution of computation and swarm intelligence and allows to explore potential embodied scenarios for decision making at the microscale. Here, we consider several relevant examples of collective intelligence and their synthetic organism counterparts.

  16. Freedom and Responsibility in Synthetic Genomics: The Synthetic Yeast Project

    OpenAIRE

    Sliva, Anna; Yang, Huanming; Boeke, Jef D.; Debra J. H. Mathews

    2015-01-01

    First introduced in 2011, the Synthetic Yeast Genome (Sc2.0) Project is a large international synthetic genomics project that will culminate in the first eukaryotic cell (Saccharomyces cerevisiae) with a fully synthetic genome. With collaborators from across the globe and from a range of institutions spanning from do-it-yourself biology (DIYbio) to commercial enterprises, it is important that all scientists working on this project are cognizant of the ethical and policy issues associated with...

  17. Asthma and Native Hawaiians/Pacific Islanders

    Science.gov (United States)

    ... Population Profiles > Native Hawaiian/Other Pacific Islander > Asthma Asthma and Native Hawaiians/Pacific Islanders Native Hawaiians/Pacific Islanders are 70 percent more likely to have asthma as non-Hispanic whites. National data for this ...

  18. Fetal Alcohol Spectrum Disorders among Native Americans

    Science.gov (United States)

    ... ISORDERS A MONG N ATIVE A MERICANS Native American cultures, which encompass American Indian, Alaska Native and Native ... among American Indians: The mythical and real properties. American Indian Culture and Research Journal 18(2):121-143. www. ...

  19. Obesity and Native Hawaiians/Pacific Islanders

    Science.gov (United States)

    ... Population Profiles > Native Hawaiian/Other Pacific Islander > Obesity Obesity and Native Hawaiians/Pacific Islanders Native Hawaiians/Pacific ... youthonline . [Accessed 05/25/2016] HEALTH IMPACT OF OBESITY More than 80 percent of people with type ...

  20. Native Speakers in Linguistic Imperialism

    DEFF Research Database (Denmark)

    Phillipson, Robert

    2016-01-01

    is recognised as desirable by some British experts, the native speakers in question seldom have this key qualification. This is even the case when the host country (Brunei) aims at bilingual education. It is unlikely that the host countries are getting value for money. Whether the UK and other ‘English...... the linguicism of British pedagogical expertise are generally involved in native speaker export businesses. They underpin a hierarchy with under-qualified native speakers projected as superior to local teachers who are seen as in need of foreign ‘aid’. In view of the British bodies involved openly declaring...

  1. The Rise of native advertising

    Directory of Open Access Journals (Sweden)

    Marius MANIC

    2015-06-01

    Full Text Available Native advertising is described both as a new way for promoters to engage audiences and as a new, clever, source of revenue for publishers and media agencies. The debates around its morality and the need for a wide accepted framework are often viewed as calls for creativity. Aside from the various forms, strategies and the need for clarification, the fact that native advertising works and its revenue estimates increase annually transforms the new type of ad into a clear objective for companies, marketers and publishers. Native advertising stopped being a buzzword and started being a marketing reality.

  2. Synthetic biology and genetic causation.

    Science.gov (United States)

    Oftedal, Gry; Parkkinen, Veli-Pekka

    2013-06-01

    Synthetic biology research is often described in terms of programming cells through the introduction of synthetic genes. Genetic material is seemingly attributed with a high level of causal responsibility. We discuss genetic causation in synthetic biology and distinguish three gene concepts differing in their assumptions of genetic control. We argue that synthetic biology generally employs a difference-making approach to establishing genetic causes, and that this approach does not commit to a specific notion of genetic program or genetic control. Still, we suggest that a strong program concept of genetic material can be used as a successful heuristic in certain areas of synthetic biology. Its application requires control of causal context, and may stand in need of a modular decomposition of the target system. We relate different modularity concepts to the discussion of genetic causation and point to possible advantages of and important limitations to seeking modularity in synthetic biology systems. Copyright © 2013 Elsevier Ltd. All rights reserved.

  3. Georeferencing on Synthetic Aperture Radar Imagery

    Science.gov (United States)

    Esmaeilzade, M.; Amini, J.; Zakeri, S.

    2015-12-01

    Due to the SAR1 geometry imaging, SAR images include geometric distortions that would be erroneous image information and the images should be geometrically calibrated. As the radar systems are side looking, geometric distortion such as shadow, foreshortening and layover are occurred. To compensate these geometric distortions, information about sensor position, imaging geometry and target altitude from ellipsoid should be available. In this paper, a method for geometric calibration of SAR images is proposed. The method uses Range-Doppler equations. In this method, for the image georeferencing, the DEM2 of SRTM with 30m pixel size is used and also exact ephemeris data of the sensor is required. In the algorithm proposed in this paper, first digital elevation model transmit to range and azimuth direction. By applying this process, errors caused by topography such as foreshortening and layover are removed in the transferred DEM. Then, the position of the corners on original image is found base on the transferred DEM. Next, original image registered to transfer DEM by 8 parameters projective transformation. The output is the georeferenced image that its geometric distortions are removed. The advantage of the method described in this article is that it does not require any control point as well as the need to attitude and rotational parameters of the sensor. Since the ground range resolution of used images are about 30m, the geocoded images using the method described in this paper have an accuracy about 20m (subpixel) in planimetry and about 30m in altimetry. 1 Synthetic Aperture Radar 2 Digital Elevation Model

  4. Space Synthetic Biology Project

    Science.gov (United States)

    Howard, David; Roman, Monsi; Mansell, James (Matt)

    2015-01-01

    Synthetic biology is an effort to make genetic engineering more useful by standardizing sections of genetic code. By standardizing genetic components, biological engineering will become much more similar to traditional fields of engineering, in which well-defined components and subsystems are readily available in markets. Specifications of the behavior of those components and subsystems can be used to model a system which incorporates them. Then, the behavior of the novel system can be simulated and optimized. Finally, the components and subsystems can be purchased and assembled to create the optimized system, which most often will exhibit behavior similar to that indicated by the model. The Space Synthetic Biology project began in 2012 as a multi-Center effort. The purpose of this project was to harness Synthetic Biology principals to enable NASA's missions. A central target for application was to Environmental Control & Life Support (ECLS). Engineers from NASA Marshall Space Flight Center's (MSFC's) ECLS Systems Development Branch (ES62) were brought into the project to contribute expertise in operational ECLS systems. Project lead scientists chose to pursue the development of bioelectrochemical technologies to spacecraft life support. Therefore, the ECLS element of the project became essentially an effort to develop a bioelectrochemical ECLS subsystem. Bioelectrochemical systems exploit the ability of many microorganisms to drive their metabolisms by direct or indirect utilization of electrical potential gradients. Whereas many microorganisms are capable of deriving the energy required for the processes of interest (such as carbon dioxide (CO2) fixation) from sunlight, it is believed that subsystems utilizing electrotrophs will exhibit smaller mass, volume, and power requirements than those that derive their energy from sunlight. In the first 2 years of the project, MSFC personnel conducted modeling, simulation, and conceptual design efforts to assist the

  5. [Imaging].

    Science.gov (United States)

    Chevrot, A; Drapé, J L; Godefroy, D; Dupont, A M; Pessis, E; Sarazin, L; Minoui, A

    1997-01-01

    The panoply of imaging techniques useful in podology is essentially limited to X-rays. Standard "standing" and "lying" X-rays furnish most of the required information. Arthrography is sometimes performed, in particular for trauma or tumour of the ankle. CT scan and MRI make a decisive contribution in difficult cases, notably in fractures and in small fractures without displacement. The two latter techniques are useful in tendon, ligament and muscular disorders, where echography is also informative. Rigorous analysis of radiographies and a good knowledge of foot disorders make these imaging techniques efficacious.

  6. Synthetic Landau levels for photons.

    Science.gov (United States)

    Schine, Nathan; Ryou, Albert; Gromov, Andrey; Sommer, Ariel; Simon, Jonathan

    2016-06-30

    Synthetic photonic materials are an emerging platform for exploring the interface between microscopic quantum dynamics and macroscopic material properties. Photons experiencing a Lorentz force develop handedness, providing opportunities to study quantum Hall physics and topological quantum science. Here we present an experimental realization of a magnetic field for continuum photons. We trap optical photons in a multimode ring resonator to make a two-dimensional gas of massive bosons, and then employ a non-planar geometry to induce an image rotation on each round-trip. This results in photonic Coriolis/Lorentz and centrifugal forces and so realizes the Fock–Darwin Hamiltonian for photons in a magnetic field and harmonic trap. Using spatial- and energy-resolved spectroscopy, we track the resulting photonic eigenstates as radial trapping is reduced, finally observing a photonic Landau level at degeneracy. To circumvent the challenge of trap instability at the centrifugal limit, we constrain the photons to move on a cone. Spectroscopic probes demonstrate flat space (zero curvature) away from the cone tip. At the cone tip, we observe that spatial curvature increases the local density of states, and we measure fractional state number excess consistent with the Wen–Zee theory, providing an experimental test of this theory of electrons in both a magnetic field and curved space. This work opens the door to exploration of the interplay of geometry and topology, and in conjunction with Rydberg electromagnetically induced transparency, enables studies of photonic fractional quantum Hall fluids and direct detection of anyons.

  7. Synthetic Landau levels for photons

    Science.gov (United States)

    Schine, Nathan; Ryou, Albert; Gromov, Andrey; Sommer, Ariel; Simon, Jonathan

    2016-06-01

    Synthetic photonic materials are an emerging platform for exploring the interface between microscopic quantum dynamics and macroscopic material properties. Photons experiencing a Lorentz force develop handedness, providing opportunities to study quantum Hall physics and topological quantum science. Here we present an experimental realization of a magnetic field for continuum photons. We trap optical photons in a multimode ring resonator to make a two-dimensional gas of massive bosons, and then employ a non-planar geometry to induce an image rotation on each round-trip. This results in photonic Coriolis/Lorentz and centrifugal forces and so realizes the Fock-Darwin Hamiltonian for photons in a magnetic field and harmonic trap. Using spatial- and energy-resolved spectroscopy, we track the resulting photonic eigenstates as radial trapping is reduced, finally observing a photonic Landau level at degeneracy. To circumvent the challenge of trap instability at the centrifugal limit, we constrain the photons to move on a cone. Spectroscopic probes demonstrate flat space (zero curvature) away from the cone tip. At the cone tip, we observe that spatial curvature increases the local density of states, and we measure fractional state number excess consistent with the Wen-Zee theory, providing an experimental test of this theory of electrons in both a magnetic field and curved space. This work opens the door to exploration of the interplay of geometry and topology, and in conjunction with Rydberg electromagnetically induced transparency, enables studies of photonic fractional quantum Hall fluids and direct detection of anyons.

  8. Life after the synthetic cell

    DEFF Research Database (Denmark)

    Rasmussen, Steen

    2010-01-01

    Nature asked eight synthetic-biology experts about the implications for science and society of the “synthetic cell” made by the J. Craig Venter Institute (JCVI). The institute's team assembled, modified and implanted a synthesized genome into a DNA-free bacterial shell to make a self-replicating ......Nature asked eight synthetic-biology experts about the implications for science and society of the “synthetic cell” made by the J. Craig Venter Institute (JCVI). The institute's team assembled, modified and implanted a synthesized genome into a DNA-free bacterial shell to make a self...

  9. Synthetic biology and occupational risk.

    Science.gov (United States)

    Howard, John; Murashov, Vladimir; Schulte, Paul

    2017-03-01

    Synthetic biology is an emerging interdisciplinary field of biotechnology that involves applying the principles of engineering and chemical design to biological systems. Biosafety professionals have done an excellent job in addressing research laboratory safety as synthetic biology and gene editing have emerged from the larger field of biotechnology. Despite these efforts, risks posed by synthetic biology are of increasing concern as research procedures scale up to industrial processes in the larger bioeconomy. A greater number and variety of workers will be exposed to commercial synthetic biology risks in the future, including risks to a variety of workers from the use of lentiviral vectors as gene transfer devices. There is a need to review and enhance current protection measures in the field of synthetic biology, whether in experimental laboratories where new advances are being researched, in health care settings where treatments using viral vectors as gene delivery systems are increasingly being used, or in the industrial bioeconomy. Enhanced worker protection measures should include increased injury and illness surveillance of the synthetic biology workforce; proactive risk assessment and management of synthetic biology products; research on the relative effectiveness of extrinsic and intrinsic biocontainment methods; specific safety guidance for synthetic biology industrial processes; determination of appropriate medical mitigation measures for lentiviral vector exposure incidents; and greater awareness and involvement in synthetic biology safety by the general occupational safety and health community as well as by government occupational safety and health research and regulatory agencies.

  10. Life after the synthetic cell

    DEFF Research Database (Denmark)

    Rasmussen, Steen

    2010-01-01

    Nature asked eight synthetic-biology experts about the implications for science and society of the “synthetic cell” made by the J. Craig Venter Institute (JCVI). The institute's team assembled, modified and implanted a synthesized genome into a DNA-free bacterial shell to make a self-replicating ......Nature asked eight synthetic-biology experts about the implications for science and society of the “synthetic cell” made by the J. Craig Venter Institute (JCVI). The institute's team assembled, modified and implanted a synthesized genome into a DNA-free bacterial shell to make a self...

  11. Computational synthetic geometry

    CERN Document Server

    Bokowski, Jürgen

    1989-01-01

    Computational synthetic geometry deals with methods for realizing abstract geometric objects in concrete vector spaces. This research monograph considers a large class of problems from convexity and discrete geometry including constructing convex polytopes from simplicial complexes, vector geometries from incidence structures and hyperplane arrangements from oriented matroids. It turns out that algorithms for these constructions exist if and only if arbitrary polynomial equations are decidable with respect to the underlying field. Besides such complexity theorems a variety of symbolic algorithms are discussed, and the methods are applied to obtain new mathematical results on convex polytopes, projective configurations and the combinatorics of Grassmann varieties. Finally algebraic varieties characterizing matroids and oriented matroids are introduced providing a new basis for applying computer algebra methods in this field. The necessary background knowledge is reviewed briefly. The text is accessible to stud...

  12. Variation and Synthetic Speech

    CERN Document Server

    Miller, C; Massey, N; Miller, Corey; Karaali, Orhan; Massey, Noel

    1997-01-01

    We describe the approach to linguistic variation taken by the Motorola speech synthesizer. A pan-dialectal pronunciation dictionary is described, which serves as the training data for a neural network based letter-to-sound converter. Subsequent to dictionary retrieval or letter-to-sound generation, pronunciations are submitted a neural network based postlexical module. The postlexical module has been trained on aligned dictionary pronunciations and hand-labeled narrow phonetic transcriptions. This architecture permits the learning of individual postlexical variation, and can be retrained for each speaker whose voice is being modeled for synthesis. Learning variation in this way can result in greater naturalness for the synthetic speech that is produced by the system.

  13. Native Terrestrial Animal Species Richness

    Data.gov (United States)

    U.S. Environmental Protection Agency — These data represent predicted current distributions of all native mammals, birds, reptiles, amphibians and butterflies in the Middle-Atlantic region. The data are...

  14. Native grassland inventory and monitoring

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — Benton Lake refuge has nearly 6,000 acres of native western wheatgrass-green needlegrass prairie uplands. This pilot study was designed to assess the condition of...

  15. Charting Transnational Native American Studies

    Directory of Open Access Journals (Sweden)

    Hsinya Huang

    2012-06-01

    Full Text Available Introduction to the Special Forum entitled "Charting Transnational Native American Studies: Aesthetics, Politics, Identity," edited by Hsinya Huang, Philip J. Deloria, Laura M. Furlan, and John Gamber

  16. The Identity (Re)Construction of Nonnative English Teachers Stepping into Native Turkish Teachers' Shoes

    Science.gov (United States)

    Mutlu, Sevcan; Ortaçtepe, Deniz

    2016-01-01

    The present study explored the identity (re)construction of five nonnative English teachers who went to the USA on a prestigious scholarship for one year to teach their native language, Turkish. In that sense, it investigated how this shift from being a nonnative English teacher to a native Turkish teacher influenced their self-image,…

  17. Structural Correlates for Lexical Efficiency and Number of Languages in Non-Native Speakers of English

    Science.gov (United States)

    Grogan, A.; Parker Jones, O.; Ali, N.; Crinion, J.; Orabona, S.; Mechias, M. L.; Ramsden, S.; Green, D. W.; Price, C. J.

    2012-01-01

    We used structural magnetic resonance imaging (MRI) and voxel based morphometry (VBM) to investigate whether the efficiency of word processing in the non-native language (lexical efficiency) and the number of non-native languages spoken (2+ versus 1) were related to local differences in the brain structure of bilingual and multilingual speakers.…

  18. Clinical validation of synthetic brain MRI in children: initial experience

    Energy Technology Data Exchange (ETDEWEB)

    West, Hollie; Leach, James L.; Jones, Blaise V.; Care, Marguerite; Radhakrishnan, Rupa; Merrow, Arnold C.; Alvarado, Enrique; Serai, Suraj D. [Cincinnati Children' s Hospital Medical Center, Department of Radiology, Cincinnati, OH (United States)

    2017-01-15

    The purpose of this study was to determine the diagnostic accuracy of synthetic MR sequences generated through post-acquisition processing of a single sequence measuring inherent R1, R2, and PD tissue properties compared with sequences acquired conventionally as part of a routine clinical pediatric brain MR exam. Thirty-two patients underwent routine clinical brain MRI with conventional and synthetic sequences acquired (22 abnormal). Synthetic axial T1, T2, and T2 fluid attenuation inversion recovery or proton density-weighted sequences were made to match the comparable clinical sequences. Two exams for each patient were de-identified. Four blinded reviewers reviewed eight patients and were asked to generate clinical reports on each exam (synthetic or conventional) at two different time points separated by a mean of 33 days. Exams were rated for overall and specific finding agreement (synthetic/conventional and compared to gold standard consensus review by two senior reviewers with knowledge of clinical report), quality, and diagnostic confidence. Overall agreement between conventional and synthetic exams was 97%. Agreement with consensus readings was 84% (conventional) and 81% (synthetic), p = 0.61. There were no significant differences in sensitivity, specificity, or accuracy for specific imaging findings involving the ventricles, CSF, brain parenchyma, or vasculature between synthetic or conventional exams (p > 0.05). No significant difference in exam quality, diagnostic confidence, or noise/artifacts was noted comparing studies with synthetic or conventional sequences. Diagnostic accuracy and quality of synthetically generated sequences are comparable to conventionally acquired sequences as part of a standard pediatric brain exam. Further confirmation in a larger study is warranted. (orig.)

  19. Native spider silk as a biological optical fiber

    Science.gov (United States)

    Huby, N.; Vié, V.; Renault, A.; Beaufils, S.; Lefèvre, T.; Paquet-Mercier, F.; Pézolet, M.; Bêche, B.

    2013-03-01

    In this study, we demonstrate the use of eco-friendly native spider silk as an efficient optical fiber in air, highly bent fibers, and physiological liquid. We also integrated the silk filament in a photonic chip made of polymer microstructures fabricated by UV lithography. The molding process is non-destructive for silk and leads to an efficient micro-optical coupling between silk and synthetic optical structures. These optical performances combined with the unique biocompatibility, bioresorbability, flexibility, and tensile strength of silk filaments pave the way for new applications in biological media and for original biophotonic purposes.

  20. Inorganic chemistry. A synthetic Mn₄Ca-cluster mimicking the oxygen-evolving center of photosynthesis.

    Science.gov (United States)

    Zhang, Chunxi; Chen, Changhui; Dong, Hongxing; Shen, Jian-Ren; Dau, Holger; Zhao, Jingquan

    2015-05-08

    Photosynthetic splitting of water into oxygen by plants, algae, and cyanobacteria is catalyzed by the oxygen-evolving center (OEC). Synthetic mimics of the OEC, which is composed of an asymmetric manganese-calcium-oxygen cluster bound to protein groups, may promote insight into the structural and chemical determinants of biological water oxidation and lead to development of superior catalysts for artificial photosynthesis. We synthesized a Mn4Ca-cluster similar to the native OEC in both the metal-oxygen core and the binding protein groups. Like the native OEC, the synthetic cluster can undergo four redox transitions and shows two magnetic resonance signals assignable to redox and structural isomerism. Comparison with previously synthesized Mn3CaO4-cubane clusters suggests that the fourth Mn ion determines redox potentials and magnetic properties of the native OEC.