Chun, Lani S.; Free, R. Benjamin; Doyle, Trevor B.; Huang, Xi-Ping; Rankin, Michele L.
The D1 dopamine receptor (D1R) has been proposed to form a hetero-oligomer with the D2 dopamine receptor (D2R), which in turn results in a complex that couples to phospholipase C–mediated intracellular calcium release. We have sought to elucidate the pharmacology and mechanism of action of this putative signaling pathway. Dopamine dose-response curves assaying intracellular calcium mobilization in cells heterologously expressing the D1 and D2 subtypes, either alone or in combination, and using subtype selective ligands revealed that concurrent stimulation is required for coupling. Surprisingly, characterization of a putative D1-D2 heteromer-selective ligand, 6-chloro-2,3,4,5-tetrahydro-3-methyl-1-(3-methylphenyl)-1H-3-benzazepine-7,8-diol (SKF83959), found no stimulation of calcium release, but it did find a broad range of cross-reactivity with other G protein–coupled receptors. In contrast, SKF83959 appeared to be an antagonist of calcium mobilization. Overexpression of Gqα with the D1 and D2 dopamine receptors enhanced the dopamine-stimulated calcium response. However, this was also observed in cells expressing Gqα with only the D1R. Inactivation of Gi or Gs with pertussis or cholera toxin, respectively, largely, but not entirely, reduced the calcium response in D1R and D2R cotransfected cells. Moreover, sequestration of Gβγ subunits through overexpression of G protein receptor kinase 2 mutants either completely or largely eliminated dopamine-stimulated calcium mobilization. Our data suggest that the mechanism of D1R/D2R–mediated calcium signaling involves more than receptor-mediated Gq protein activation, may largely involve downstream signaling pathways, and may not be completely heteromer-specific. In addition, SKF83959 may not exhibit selective activation of D1-D2 heteromers, and its significant cross-reactivity to other receptors warrants careful interpretation of its use in vivo. PMID:23680635
Nasanit, Rujikan; Jaibangyang, Sopin; Tantirungkij, Manee; Limtong, Savitree
Culture-independent techniques have recently been used for evaluation of microbial diversity in the environment since it addresses the problem of unculturable microorganisms. In this study, the diversity of epiphytic yeasts from corn (Zea mays Linn.) phylloplanes in Thailand was investigated using this technique and sequence-based analysis of the D1/D2 domains of the large subunit ribosomal DNA sequences. Thirty-seven samples of corn leaf were collected randomly from 10 provinces. The DNA was extracted from leaf washing samples and the D1/D2 domains were amplified. The PCR products were cloned and then screened by colony PCR. A total of 1049 clones were obtained from 37 clone libraries. From this total, 329 clones (213 sequences) were closely related to yeast strains in the GenBank database, and they were clustered into 77 operational taxonomic units (OTUs) with a similarity threshold of 99 %. The majority of sequences (98.5 %) were classified into the phylum Basidiomycota. Sixteen known yeast species were identified. Interestingly, more than 65 % of the D1/D2 sequences obtained by this technique were suggested to be sequences from new yeast taxa. The predominant yeast sequences detected belonged to the order Ustilaginales with relative frequency of 68.0 %. The most common known yeast species detected on the leaf samples were Pseudozyma hubeiensis pro tem. and Moesziomyces antarcticus with frequency of occurrence of 24.3 and 21.6 %, respectively.
Strijker, Marin; Gerritsen, Arja; van Hilst, Jony; Bijlsma, Maarten F; Bonsing, Bert A; Brosens, Lodewijk A; Bruno, Marco J; van Dam, Ronald M; Dijk, Frederike; van Eijck, Casper H; Farina Sarasqueta, Arantza; Fockens, Paul; Gerhards, Michael F; Groot Koerkamp, Bas; van der Harst, Erwin; de Hingh, Ignace H; van Hooft, Jeanin E; Huysentruyt, Clément J; Kazemier, Geert; Klaase, Joost M; van Laarhoven, Cornelis J; van Laarhoven, Hanneke W; Liem, Mike S; de Meijer, Vincent E; van Rijssen, L Bengt; van Santvoort, Hjalmar C; Suker, Mustafa; Verhagen, Judith H; Verheij, Joanne; Verspaget, Hein W; Wennink, Roos A; Wilmink, Johanna W; Molenaar, I Quintus; Boermeester, Marja A; Busch, Olivier R; Besselink, Marc G
Large biobanks with uniform collection of biomaterials and associated clinical data are essential for translational research. The Netherlands has traditionally been well organized in multicenter clinical research on pancreatic diseases, including the nationwide multidisciplinary Dutch Pancreatic Cancer Group and Dutch Pancreatitis Study Group. To enable high-quality translational research on pancreatic and periampullary diseases, these groups established the Dutch Pancreas Biobank. The Dutch Pancreas Biobank is part of the Parelsnoer Institute and involves all 8 Dutch university medical centers and 5 nonacademic hospitals. Adult patients undergoing pancreatic surgery (all indications) are eligible for inclusion. Preoperative blood samples, tumor tissue from resected specimens, pancreatic cyst fluid, and follow-up blood samples are collected. Clinical parameters are collected in conjunction with the mandatory Dutch Pancreatic Cancer Audit. Between January 2015 and May 2017, 488 patients were included in the first 5 participating centers: 4 university medical centers and 1 nonacademic hospital. Over 2500 samples were collected: 1308 preoperative blood samples, 864 tissue samples, and 366 follow-up blood samples. Prospective collection of biomaterials and associated clinical data has started in the Dutch Pancreas Biobank. Subsequent translational research will aim to improve treatment decisions based on disease characteristics.
Full Text Available The present study evaluated the effect of osthole, an active ingredient isolated from Cnidium monnieri L. Cusson, on spatial memory deficits caused by central neurotoxins using the Morris water maze in rats. The involvement of catecholaminergic receptors on the memory-enhancing effect of osthole in rat hippocampus was further investigated by intrahippocampal injection of catecholaminergic receptor antagonists. Intracisternal injection of osthole (10 μg/brain improved the spatial performance and working memory impairments caused by the catecholaminergic neurotoxin 6-hydroxydopamine. No significant differences in swimming speeds were observed among sham, neurotoxin-induced, and osthole-treated groups. Intracisternal osthole injection also attenuated the spatial performance and working memory impairments caused by the α1 receptor antagonist phenoxybenzamine, the D1 receptor antagonist SCH 23390, and the D2 receptor antagonist sulpiride. Therefore, we demonstrated that the effect of osthole on improving spatial memory deficits may be related to the activation of hippocampal α1 and D1/D2 receptors.
Ma, Kai; Liu, Guang-quan; Li, Jin-xia; Yao, Su; Cheng, Chi
The 26S rRNA gene D1/D2 domain sequences of 15 strains originally identified as Galactomyces geotrichum from the Chinese Industry Culture Collection (CICC) were determined. The results indicated that these strains differed from the type strain of Galactomyces geotrichum and other species of the genus remarkably. Two groups were recognized from the 15 strains which possibly represent 2 novel species of Galactomyces. Further molecular study is needed to confirm their taxonomic status.
Dammalapati, U.; Norris, I.; Burrows, C.; Riis, E.
Laser excitation of the 4s4p(3) P-2-4s3d(1) D-2 transition in atomic calcium has been observed and the wavelength determined to 1530.5298(6) nm. The metastable 4s4p(3) P-2 atoms were magnetically trapped in the quadrupole magnetic field of a magneto-optical trap. This state represents the only
Karabinos, Anton; Schünemann, Jürgen; Parry, David A D
The dimerisation properties of six intestine-expressed intermediate filament (IF) proteins (B2, C1, C2, D1, D2, E1) were analysed in blot overlay assay on membranes containing all of the eleven recombinant C. elegans IF proteins (A1, A2, A3, A4, B1, B2, C1, C2, D1, D2, and E1). The interactions detected in the blot assays exclusively comprise intestine-expressed IF proteins and the protein A4, which is found in the dauer larva intestine. About 86% of these interactions are heterotypic, while the remaining interactions relate to C1, C2, and D2 homodimers. These multiple modes of interaction were also supported by calculations of the numbers of possible interchain ionic interactions derived from the individual rod sequences. The results predict that the six B2, C1, C2, D1, D2, and E1 IF proteins are able to form as many as eleven different heteropolymeric and three homopolymeric IFs in the C. elegans intestine. This simple model of the intestinal IF meshwork enables us to speculate that our previously reported triple RNAi worms arrested or decreased their growth because of feeding reduction due to morphological defects of the mechanically compromised intestine. © 2017 Wiley Periodicals, Inc.
Trost, Alexandra; Hauber, Wolfgang
Rats lever-press for access to running wheels suggesting that wheel running by itself is reinforcing. Furthermore, pairings of an episode of wheel running and subsequent confinement in a specific environment can establish a conditioned place preference (CPP). This finding implies that the reinforcing effects of wheel running outlast the actual occurrence of physical activity, a phenomenon referred to as aftereffect of wheel running. Aftereffect-induced CPP involves Pavlovian conditioning, i.e. repeated pairings of the aftereffect of wheel running with a specific environment creates a learned association between aftereffect and environment and, in turn, a preference for that environment. Given the involvement of dopamine systems in mediating effects of Pavlovian stimuli on appetitive behavior, a role of dopamine in mediating aftereffect-induced CPP seems plausible. Here we assessed whether the mixed D1/D2 receptor antagonist flupenthixol (0.25 mg/kg, i.p.) can block the expression of an aftereffect-induced CPP. In line with earlier studies, our results demonstrate that rats displayed a conditioned preference for environments paired with the aftereffect of wheel running and further show that the magnitude of CPP was not related to the wheel running rate. Furthermore, we found that flupenthixol (0.25 mg/kg, i.p.) reduced locomotor activity but did not attenuate the expression of an aftereffect-induced CPP. The expression of a CPP produced by the aftereffect of wheel running seems not to depend on dopamine D1/D2 receptor activation.
Schönbeck, Y.; Talma, H.; Dommelen, P. van; Bakker, B.; Buitendijk, S.E.; HiraSing, R.A.; Buuren, S. van
To assess the prevalence of overweight and obesity among Dutch children and adolescents, to examine the 30-years trend, and to create new body mass index reference charts. Design: Nationwide cross-sectional data collection by trained health care professionals. Participants: 10,129 children of Dutch
Full Text Available The dopamine D(1, D(2, D(3 receptors, vesicular monoamine transporter type-2 (VMAT2, and dopamine transporter (DAT densities were measured in 11 aged human brains (aged 77-107.8, mean: 91 years by quantitative autoradiography. The density of D(1 receptors, VMAT2, and DAT was measured using [(3H]SCH23390, [(3H]dihydrotetrabenazine, and [(3H]WIN35428, respectively. The density of D(2 and D(3 receptors was calculated using the D(3-preferring radioligand, [(3H]WC-10 and the D(2-preferring radioligand [(3H]raclopride using a mathematical model developed previously by our group. Dopamine D(1, D(2, and D(3 receptors are extensively distributed throughout striatum; the highest density of D(3 receptors occurred in the nucleus accumbens (NAc. The density of the DAT is 10-20-fold lower than that of VMAT2 in striatal regions. Dopamine D(3 receptor density exceeded D(2 receptor densities in extrastriatal regions, and thalamus contained a high level of D(3 receptors with negligible D(2 receptors. The density of dopamine D(1 linearly correlated with D(3 receptor density in the thalamus. The density of the DAT was negligible in the extrastriatal regions whereas the VMAT2 was expressed in moderate density. D(3 receptor and VMAT2 densities were in similar level between the aged human and aged rhesus brain samples, whereas aged human brain samples had lower range of densities of D(1 and D(2 receptors and DAT compared with the aged rhesus monkey brain. The differential density of D(3 and D(2 receptors in human brain will be useful in the interpretation of PET imaging studies in human subjects with existing radiotracers, and assist in the validation of newer PET radiotracers having a higher selectivity for dopamine D(2 or D(3 receptors.
Full Text Available A significant subpopulation of neurons in rat nucleus accumbens (NAc coexpress dopamine D1 and D2 receptors, which can form a D1-D2 receptor complex, but their relevance in addiction is not known. The existence of the D1-D2 heteromer in the striatum of rat and monkey was established using in situ PLA, in situ FRET and co-immunoprecipitation. In rat, D1-D2 receptor heteromer activation led to place aversion and abolished cocaine CPP and locomotor sensitization, cocaine intravenous self-administration and reinstatement of cocaine seeking, as well as inhibited sucrose preference and abolished the motivation to seek palatable food. Selective disruption of this heteromer by a specific interfering peptide induced reward-like effects and enhanced the above cocaine-induced effects, including at a subthreshold dose of cocaine. The D1-D2 heteromer activated Cdk5/Thr75-DARPP-32 and attenuated cocaine-induced pERK and ΔFosB accumulation, together with inhibition of cocaine-enhanced local field potentials in NAc, blocking thus the signaling pathway activated by cocaine: D1R/cAMP/PKA/Thr34-DARPP-32/pERK with ΔFosB accumulation. In conclusion, our results show that the D1-D2 heteromer exerted tonic inhibitory control of basal natural and cocaine reward, and therefore initiates a fundamental physiologic function that limits the liability to develop cocaine addiction.
van Rijssen, L. Bengt; Koerkamp, Bas G.; Zwart, Maurice J.; Bonsing, Bert A.; Bosscha, Koop; van Dam, Ronald M.; van Eijck, Casper H.; Gerhards, Michael F.; van der Harst, Erwin; de Hingh, Ignace H.; de Jong, Koert P.; Kazemier, Geert; Klaase, Joost; van Laarhoven, Cornelis J.; Molenaar, I. Quintus; Patijn, Gijs A.; Rupert, Coen G.; van Santvoort, Hjalmar C.; Scheepers, Joris J.; van der Schelling, George P.; Busch, Olivier R.; Besselink, Marc G.; Bollen, Thomas L.; Bruno, Marco J.; van Tienhoven, Geert-Jan; Norduyn, Arnold; Berry, David P.; Tingstedt, Bobby; Tseng, Jennifer F.; Wolfgang, Christopher L.
Background: Auditing is an important tool to identify practice variation and 'best practices'. The Dutch Pancreatic Cancer Audit is mandatory in all 18 Dutch centers for pancreatic surgery. Methods: Performance indicators and case-mix factors were identified by a PubMed search for randomized
De Reu, Paul; Van Diem, Mariet; Eskes, Martine; Oosterbaan, Herman; Smits, Luc; Merkus, Hans; Nijhuis, Jan
Objective. To investigate the feasibility of nationwide perinatal mortality audits in the Netherlands. Study design. Over a one-year period, data for all cases of perinatal mortality were collected. Six perinatal audit panels of professionals within perinatal care investigated and classified causes
Differentiation of Candida glabrata, C. nivariensis and C. bracarensis based on fragment length polymorphism of ITS1 and ITS2 and restriction fragment length polymorphism of ITS and D1/D2 regions in rDNA
Mirhendi, H; Bruun, B; Schønheyder, H C
Different molecular methods for the discrimination of Candida glabrata, C. bracarensis and C. nivariensis were evaluated and the prevalence of these species among Danish blood isolates investigated. Control strains were used to determine fragment length polymorphism in the ITS1, ITS2, ITS1-5.8S...... enzymes were suitable for RFLP differentiation of the species. Enzymatic digestion of the D1/D2 domain with TatI produced unique band sizes for each of the three species. PCR-RFLP and PNA-FISH were in agreement for all of the isolates tested. None of the 133 Danish blood isolates were C. nivariensis or C....... bracarensis. Fragment size polymorphism of ITS1 and RFLP of the D1/D2 domain or the ITS region are useful methods for the differentiation of the species within the C. glabrata group. C. bracarensis and C. nivariensis are rare among Danish C. glabrata blood isolates....
Wilson, James B. [Molecular Oncology and Stem Cell Research Group, School of Biological Sciences, University of Liverpool, Biosciences Building, Crown Street, Liverpool L69 7ZB (United Kingdom); Blom, Eric [Department of Clinical Genetics and Human Genetics, VU University Medical Center, Van der Boechorststraat 7, NL-1081 BT Amsterdam (Netherlands); Cunningham, Ryan; Xiao, Yuxuan [Molecular Oncology and Stem Cell Research Group, School of Biological Sciences, University of Liverpool, Biosciences Building, Crown Street, Liverpool L69 7ZB (United Kingdom); Kupfer, Gary M. [Departments of Pediatrics and Pathology, Yale University School of Medicine, Section of Hematology/Oncology, 333 Cedar Street, New Haven, CT 0652 (United States); Jones, Nigel J., E-mail: firstname.lastname@example.org [Molecular Oncology and Stem Cell Research Group, School of Biological Sciences, University of Liverpool, Biosciences Building, Crown Street, Liverpool L69 7ZB (United Kingdom)
The Fanconi anaemia (FA) FANCG protein is an integral component of the FA nuclear core complex that is required for monoubiquitylation of FANCD2. FANCG is also part of another protein complex termed D1-D2-G-X3 that contains FANCD2 and the homologous recombination repair proteins BRCA2 (FANCD1) and XRCC3. Formation of the D1-D2-G-X3 complex is mediated by serine-7 phosphorylation of FANCG and occurs independently of the FA core complex and FANCD2 monoubiquitylation. FANCG contains seven tetratricopeptide repeat (TPR) motifs that mediate protein-protein interactions and here we show that mutation of several of the TPR motifs at a conserved consensus residue ablates the in vivo binding activity of FANCG. Expression of mutated TPR1, TPR2, TPR5 and TPR6 in Chinese hamster fancg mutant NM3 fails to functionally complement its hypersensitivities to mitomycin C (MMC) and phleomycin and fails to restore FANCD2 monoubiquitylation. Using co-immunoprecipitation analysis, we demonstrate that these TPR-mutated FANCG proteins fail to interact with BRCA2, XRCC3, FANCA or FANCF. The interactions of other proteins in the D1-D2-G-X3 complex are also absent, including the interaction of BRCA2 with both the monoubiquitylated (FANCD2-L) and non-ubiquitylated (FANCD2-S) isoforms of FANCD2. Interestingly, a mutation of TPR7 (R563E), that complements the MMC and phleomycin hypersensitivity of human FA-G EUFA316 cells, fails to complement NM3, despite the mutated FANCG protein co-precipitating with FANCA, BRCA2 and XRCC3. Whilst interaction of TPR7-mutated FANCG with FANCF does appear to be reduced in NM3, FANCD2 is monoubiquitylated suggesting that sub-optimal interactions of FANCG in the core complex and the D1-D2-G-X3 complex are responsible for the observed MMC- and phleomycin-hypersensitivity, rather than a defect in FANCD2 monoubiquitylation. Our data demonstrate that FANCG functions as a mediator of protein-protein interactions and is vital for the assembly of multi-protein complexes
Yoo, Ji-Hoon; Bailey, Alexis; Ansonoff, Micheal; Pintar, John E.; Matifas, Audrey; Kieffer, Brigitte L.; Kitchen, Ian
We investigated D1, D2 receptors and dopamine transporter (DAT) binding levels in mice lacking all three opioid receptors and wild-type (WT) mice on three different genetic backgrounds. Quantitative autoradiography was used to determine the level of radioligand binding to the D1 and D2 receptors and DAT labeled with [3H]SCH23390, [3H]raclopride, and [3H]mazindol, respectively in triple-opioid receptor knockout (KO) and WT maintained on C57BL/6 (B6) and 129/SvEvTac (129) as well as C57BL/6 × 129/SvPas (B6 × 129) strains. No significant genotype effect was observed in D1, D2 receptors and DAT binding in any regions analyzed in any of the strains studied, suggesting that a lack of all three opioid receptors does not influence D1, D2 receptors and DAT expression, irrespective of their genetic strain background. However, strain differences were observed in D1 binding between the three strains of mice studied. Lower levels of D1 binding were observed in the substantia nigra of B6 × 129 WT mice compared with the 129 WT mice and in the olfactory tubercle of B6 × 129 WT compared with B6 WT and 129 WT mice. Lower levels of D1 binding were observed in the caudate putamen of B6 × 129 KO mice compared with 129 KO mice. In contrast, no significant strain differences were observed in D2 and DAT binding between the three strains of mice in any regions analyzed. Overall, these results indicate a lack of modulation of the dopaminergic system by the deletion of all three opioid receptors regardless of different background strains. PMID:20196137
Maurits, Erica E M; de Veer, Anke J E; Groenewegen, Peter P; Francke, Anneke L
The World Health Organization is calling for a fundamental change in healthcare services delivery, towards people-centred and integrated health services. This includes providing integrated care around people's needs that is effectively co-ordinated across providers and co-produced by professionals, the patient, the family and the community. At the same time, healthcare policies aim to scale back hospital and residential care in favour of home care. This is one reason for the home-care nursing staff shortages in Europe. Therefore, this study aimed to examine whether people-centred, integrated home care appeals to nurses with different levels of education in home care and hospitals. A questionnaire survey was held among registered nurses in Dutch home-care organisations and hospitals in 2015. The questionnaire addressed the perceived attractiveness of different aspects of people-centred, integrated home care. In total 328 nurses filled in the questionnaire (54% response rate). The findings showed that most home-care nurses (70% to 97%) and 36% to 76% of the hospital nurses regard the different aspects of people-centred, integrated home care as attractive. Specific aspects that home-care nurses find attractive are promoting the patient's self-reliance and having a network in the community. Hospital nurses are mainly attracted to health-related prevention and taking control in complex situations. No clear differences between the educational levels were found. It is concluded that most home-care nurses and a minority of hospital nurses feel attracted to people-centred, integrated home care, irrespective of their educational level. The findings are relevant to policy makers and home-care organisations who aim to expand the home-care nursing workforce. © 2018 John Wiley & Sons Ltd.
Sun, Haifeng; Zhu, Liyuan; Yang, Huicui; Qian, Wangke; Guo, Lin; Zhou, Shengbin; Gao, Bo; Li, Zeng; Zhou, Yu; Jiang, Hualiang; Chen, Kaixian; Zhen, Xuechu; Liu, Hong
An effective and rapid method for the microwave-assisted preparation of the key intermediate for the total synthesis of tetrahydroprotoberberines (THPBs) including l-stepholidine (l-SPD) was developed. Thirty-one THPB derivatives with diverse substituents on A and D ring were synthesized, and their binding affinity to dopamine D(1), D(2) and serotonin 5-HT(1A) and 5-HT(2A) receptors were determined. Compounds 18k and 18m were identified as partial agonists at the D(1) receptor with K(i) values of 50 and 6.3nM, while both compounds act as D(2) receptor antagonists (K(i)=305 and 145nM, respectively) and 5-HT(1A) receptor full agonists (K(i)=149 and 908nM, respectively). These two THPBs compounds exerted antipsychotic actions in animal models. Further electrophysiological studies employing single-unit recording in intact animals demonstrated that 18k-excited dopaminergic (DA) neurons are associated with its 5-HT(1A) receptor agonistic activity. These results suggest that these two compounds targeted to multiple neurotransmitter receptors may present novel lead drugs with new pharmacological profiles for the treatment of schizophrenia. Copyright © 2012 Elsevier Ltd. All rights reserved.
Jonkman, Sebastiaan N; Jongejan, Ruben; Maaskant, Bob
The Dutch government is in the process of revising its flood safety policy. The current safety standards for flood defenses in the Netherlands are largely based on the outcomes of cost-benefit analyses. Loss of life has not been considered separately in the choice for current standards. This article presents the results of a research project that evaluated the potential roles of two risk metrics, individual and societal risk, to support decision making about new flood safety standards. These risk metrics are already used in the Dutch major hazards policy for the evaluation of risks to the public. Individual risk concerns the annual probability of death of a person. Societal risk concerns the probability of an event with many fatalities. Technical aspects of the use of individual and societal risk metrics in flood risk assessments as well as policy implications are discussed. Preliminary estimates of nationwide levels of societal risk are presented. Societal risk levels appear relatively high in the southwestern part of the country where densely populated dike rings are threatened by a combination of river and coastal floods. It was found that cumulation, the simultaneous flooding of multiple dike rings during a single flood event, has significant impact on the national level of societal risk. Options for the application of the individual and societal risk in the new flood safety policy are presented and discussed. © 2010 Society for Risk Analysis.
This paper integrates the interorganisational innovation process and national innovation system-approach into a new model. A case study research project that covers a 16-year period of sustainable innovations in the Dutch residential building industry applies the model. The research outcomes
Heijer, C.D.J. den; Penders, J.; Donker, G.A.; Bruggeman, C.A.; Stobberingh, E.E.
Few studies have been performed on urinary tract infections (UTIs) in men. In the present study, general practitioners (n = 42) from the Dutch Sentinel General Practice Network collected urinary samples from 560 male patients (≥18 years) suspected of UTI and recorded prescribed antibiotic treatment.
B.M. Wammes (Birgitte)
textabstractThe prevalence of overweight and obesity is increasing rapidly. In the Netherlands, the prevalence of obesity has roughly doubled over the last decade and now more than 40% of the Dutch adult population is overweight and more than 10% obese. To promote weight-gain preventive actions
Bijwaard, H; de Vries, G; Scheurleer, J; Roding, T; Erenstein, H; Ravensbergen, W; Haarmans-Jonkman, S; van Welie, F
In the Netherlands, hospitals have difficulty in implementing the formal procedure of comparing radiation dose values to Diagnostic Reference Levels (DRLs). To support the hospitals, train radiography students, and carry out a nationwide dose survey, diagnostic radiography students performed 125 DRL comparisons for nine different procedures in 29 radiology departments. Students were instructed at three Dutch Universities of Applied Sciences with a radiography programme and supervised by medical physicists from the participating hospitals. After a pilot study in the western part of the country in eight hospitals, this study was enlarged to involve 21 hospitals from all over the Netherlands. The 86 obtained dose comparisons fall below the DRLs in 97% of all cases. This very high compliance may have been enhanced by the voluntary participation of hospitals that are confident about their performance. The results indicate that the current DRLs that were not based on a national survey, may need to be updated, sometimes to half their current value. For chest and pelvis examinations the DRLs could be lowered from 12 and 300 μGy·m 2 to the 75-percentile values found in this study of 5,9 and 188 μGy·m 2 , respectively. Copyright © 2017 The College of Radiographers. Published by Elsevier Ltd. All rights reserved.
Fallah Arani, S; Balak, D M W; Neumann, H A M; Kuipers, M V; Thio, H B
Psoriasis vulgaris is a T-cell mediated disease that affects 2-3% of the worldwide white-skinned population. Fumaric acid esters are mentioned as an effective therapy for moderate-to-severe psoriasis vulgaris in adult patients in the new guidelines for psoriasis treatment. To obtain an insight into the use of fumaric acid esters by Dutch dermatologists in the Netherlands. This was a cross-sectional postal survey. An anonymous survey was posted to all Dutch dermatologists. In this survey, data were collected on the extent of fumaric acid esters use, the reasons for use, the reasons for non- or limited use of fumaric acid esters, the perception of fumaric acid esters as a mono-therapy with regards to the effectiveness, the safety, the adverse events and the overall satisfaction of fumaric acid esters as a mono-therapy. Sixty-three per cent of the 300 responders indicated to prescribe fumaric acid esters for the treatment of psoriasis. About 37% of the dermatologists indicated (almost) never to prescribe it. Biologicals were considered as the most effective therapy. Fumaric acid esters were regarded as the safest therapy. They were generally well-tolerated by the patients similar to that for methotrexate according to the respondents. A large proportion of the dermatologists in our survey indicated to prescribe fumaric acid esters. It is considered to be effective, safe and without adverse events profile that is favourable in the practice, also as compared with other systemic therapies such as methotrexate and biologicals. © 2013 European Academy of Dermatology and Venereology.
Pouwer, A W; Hinten, F; van der Velden, J; Smolders, R G V; Slangen, B F M; Zijlmans, H J M A A; IntHout, J; van der Zee, A G J; Boll, D; Gaarenstroom, K N; Arts, H J; de Hullu, J A
Inguinofemoral lymphadenectomy for patients with vulvar squamous cell carcinoma is associated with a high incidence of postoperative wound complications, which may be influenced by inguinal drain management. The aim of this nationwide prospective study (MAMBO: Morbidity And Measurement of the BOdy) was to assess the feasibility and the incidence of complications after volume-controlled versus short drainage. The MAMBO study consisted of two observational studies in all eight oncology centers in the Netherlands, conducted between 2012 and 2016. In the first study, the drain was removed when the production was drainage protocols, adjusting for possible confounders. We included 77 patients (139 groins) for volume-controlled drainage and 64 patients (112 groins) for short drainage. Volume-controlled drainage was associated with significant less lymphocele formation. Moreover, we found no difference in wound infection or primary wound breakdown. The estimated incidence of one or more complications was 46% per groin after volume-controlled drainage versus 75% after short drainage, (RD 29% (95% CI 8, 49) p=0.006). This prospective study shows that volume-controlled drainage is associated with significantly less complications compared to short drainage. We therefore recommend volume-controlled drainage after inguinofemoral lymphadenectomy in patients with vulvar squamous cell carcinoma. Copyright © 2017 Elsevier Inc. All rights reserved.
Spekhorst, Lieke M; Imhann, Floris; Festen, Eleonora Am; Bodegraven, Ad A van; Boer, Nanne Kh de; Bouma, Gerd; Fidder, Herma H; D'Haens, Geert; Hoentjen, Frank; Hommes, Daan W; Jong, Dirk J de; Löwenberg, Mark; Maljaars, Pw Jeroen; Meulen-de Jong, Andrea E van der; Oldenburg, Bas; Pierik, Marieke J; Ponsioen, Cyriel Y; Stokkers, Pieter C; Verspaget, Hein W; Visschedijk, Marijn C; van der Woude, C Janneke; Dijkstra, Gerard; Weersma, Rinse K
PURPOSE: The Dutch IBD Biobank aims to facilitate the discovery of predictors for individual disease course and treatment response in patients with inflammatory bowel disease (IBD). In this paper, we aim to describe the establishment of the Dutch IBD Biobank, including the facilitators and barriers
Spekhorst, Lieke M.; Imhann, Floris; Festen, Eleonora A. M.; van Bodegraven, Ad A.; de Boer, Nanne K. H.; Bouma, Gerd; Fidder, Herma H.; D'Haens, Geert; Hoentjen, Frank; Hommes, Daan W.; de Jong, Dirk J.; Löwenberg, Mark; Maljaars, P. W. Jeroen; van der Meulen-de Jong, Andrea E.; Oldenburg, Bas; Pierik, Marieke J.; Ponsioen, Cyriel Y.; Stokkers, Pieter C.; Verspaget, Hein W.; Visschedijk, Marijn C.; van der Woude, C. Janneke; Dijkstra, Gerard; Weersma, Rinse K.
The Dutch IBD Biobank aims to facilitate the discovery of predictors for individual disease course and treatment response in patients with inflammatory bowel disease (IBD). In this paper, we aim to describe the establishment of the Dutch IBD Biobank, including the facilitators and barriers to
Spekhorst, Lieke M; Imhann, Floris; Festen, Eleonora A M; van Bodegraven, Ad A; de Boer, Nanne K H; Bouma, Gerd; Fidder, Herma H; d'Haens, Geert; Hoentjen, Frank; Hommes, Daan W; de Jong, Dirk J; Löwenberg, Mark; Maljaars, P W Jeroen; van der Meulen-de Jong, Andrea E; Oldenburg, Bas; Pierik, Marieke J; Ponsioen, Cyriel Y; Stokkers, Pieter C; Verspaget, Hein W; Visschedijk, Marijn C; van der Woude, C Janneke; Dijkstra, Gerard; Weersma, Rinse K
The Dutch IBD Biobank aims to facilitate the discovery of predictors for individual disease course and treatment response in patients with inflammatory bowel disease (IBD). In this paper, we aim to describe the establishment of the Dutch IBD Biobank, including the facilitators and barriers to establishment. Moreover, we aim to provide a complete overview of the content of the Dutch IBD Biobank. Since 2007, every patient with IBD treated in one of the eight Dutch university medical centres is asked to participate in the Dutch IBD Biobank in which 225 standardised IBD-related data items and biomaterials, such as serum, DNA, biopsies and a stool sample, are collected. As of June 2014, the Dutch IBD Biobank had enrolled 3388 patients with IBD: 2118 Crohn's disease (62.5%), 1190 ulcerative colitis (35.1%), 74 IBD-unclassified (2.2%) and 6 IBD-indeterminate (0.2%). The inclusion of patients with IBD is ongoing. The quality of the biomaterials is good and serum, DNA and biopsies have been used in newly published studies. The genotyping (750 000 genetic variants) of all participants of the Dutch IBD Biobank is currently ongoing, enabling more genetic research. In addition, all participants will start reporting disease activity and outcome measures using an online platform and mobile app . © Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2017. All rights reserved. No commercial use is permitted unless otherwise expressly granted.
van Leersum, N. J.; Snijders, H. S.; Henneman, D.; Kolfschoten, N. E.; Gooiker, G. A.; ten Berge, M. G.; Eddes, E. H.; Wouters, M. W. J. M.; Tollenaar, R. A. E. M.; Bemelman, W. A.; van Dam, R. M.; Elferink, M. A.; Karsten, Th M.; van Krieken, J. H. J. M.; Lemmens, V. E. P. P.; Rutten, H. J. T.; Manusama, E. R.; van de Velde, C. J. H.; Meijerink, W. J. H. J.; Wiggers, Th; van der Harst, E.; Dekker, J. W. T.; Boerma, D.
In 2009, the nationwide Dutch Surgical Colorectal Audit (DSCA) was initiated by the Association of Surgeons of the Netherlands (ASN) to monitor, evaluate and improve colorectal cancer care. The DSCA is currently widely used as a blueprint for the initiation of other audits, coordinated by the Dutch
Fijn, R; Brouwers, JRBJ; Knaap, RJ; De Jong-Van den Berg, LTW
Aims To determine structure, activities and drug selection processes used by Dutch hospital drug and therapeutics (D & T) committees. Methods A pretested structured survey questionnaire based on the Australian process and impact indicators, previous research, and consultation of professionals was
Jonkman, S.N.; Jongejan, R.B.; Maaskant, B.
The Dutch government is in the process of revising its flood safety policy. The current safety standards for flood defences in the Netherlands are largely based on the outcomes of cost-benefit analyses. Loss of life has not been considered separately in the choice for current standards. This article
Schellevis François G
Full Text Available Abstract Background We aimed to investigate incidence rates of urinary tract infections in Dutch general practice and their association with gender, season and urbanisation level, and to analyse prescription and referral in case of urinary tract infections. Method During one calendar year, 195 general practitioners in 104 practices in the Netherlands registered all their patient contacts. This study was performed by the Netherlands Institute for Health Services Research (NIVEL in 2001. Of 82,053 children aged 0 to 18 years, the following variables were collected: number of episodes per patient, number of contacts per episode, month of the year in which the diagnosis of urinary tract infection was made, age, gender, urbanisation level, drug prescription and referral. Results The overall incidence rate was 19 episodes per 1000 person years. The incidence rate in girls was 8 times as high as in boys. The incidence rate in smaller cities and rural areas was 2 times as high as in the three largest cities. Throughout the year, incidence rates varied with a decrease in summertime for children at the age of 0 to 12 years. Of the prescriptions, 66% were in accordance with current guidelines, but only 18% of the children who had an indication were actually referred. Conclusion This study shows that incidence rates of urinary tract infections are not only related to gender and season, but also to urbanisation. General practitioners in the Netherlands frequently do not follow the clinical guidelines for urinary tract infections, especially with respect to referral.
Leersum, N.J. van; Snijders, H.S.; Henneman, D.; Kolfschoten, N.E.; Gooiker, G.A.; Berge, M.G. Ten; Eddes, E.H.; Wouters, M.W.; Tollenaar, R.A.E.M.; Bemelman, W.A.; Dam, R.M. van; Elferink, M.A.; Karsten, T.M.; Krieken, J.H. van; Lemmens, V.E.; Rutten, H.J.; Manusama, E.R.; Velde, C.J. van de; Meijerink, W.J.H.J.; Wiggers, T.; Harst, E. van der; Dekker, J.W.T.; Boerma, D.
INTRODUCTION: In 2009, the nationwide Dutch Surgical Colorectal Audit (DSCA) was initiated by the Association of Surgeons of the Netherlands (ASN) to monitor, evaluate and improve colorectal cancer care. The DSCA is currently widely used as a blueprint for the initiation of other audits, coordinated
Joep de Hart
Original title: Landelijk verenigd. Is it the case that the Dutch increasingly maintain only passive relationships with organisations? Is it true that clubs and societies are faced with a falling percentage of active members and volunteers? Is a trend under way in Dutch civil society in
Drug adherence and multidisciplinary care in patients with multiple sclerosis: Protocol of a prospective, web-based, patient-centred, nation-wide, Dutch cohort study in glatiramer acetate treated patients (CAIR study
an investigator-initiated, prospective, web-based, patient-centred, nation-wide cohort study in the Netherlands. The primary objective is to investigate whether GA adherence is associated with specific disciplines of care or quantities of specific care. The secondary objective is to investigate whether GA adherence is associated with specific aspects of the socio-economic situation, health care and caregivers, disease, treatment or patient characteristics. All data are acquired on-line via a study website. All RRMS patients in the Netherlands starting GA treatment are eligible. Patients are informed by neurologists, nurses, and websites from national MS patient organisations. All data, except on disability, are obtained by patient self-reports on pre-defined and random time points. The number of missed doses and the number of patients having discontinued GA treatment at 6 and 12 months are measures of adherence. Per care discipline the number of sessions and the total duration of care are measures of received care. The full spectrum of non-experimental care that is available in the Netherlands is assessed. Care includes 'physical' contacts, contacts by telephone or internet, health-promoting activities and community care activities. Care received over the preceding 14 days is assessed by patients at baseline and every other week thereafter up to month 12. Every 3 months neurologists and nurses record care disciplines to which patients have been referred. The Dutch Adherence Questionnaire-90 (DAQ-90 is a 90-item questionnaire based on the World Health Organisation (WHO 2003 report on adherence and comprehensively assesses five domains of evidence-based determinants of adherence: socio-economic, health care and caregivers, disease, treatment, and patient-related factors. In addition, self-efficacy is assessed by the MS Self-Efficacy Scale (MSSES, and mood and health-related quality of life (HRQoL by the Multiple Sclerosis Quality of Life-54 questionnaire (MSQoL-54
This course in colloquial Dutch was originally prepared for use by American Armed Forces personnel who needed to develop a working command of the spoken language in a short period of time. Thirty-one lessons, based on activities common to Dutch culture, are contained in the text. Each lesson provides three parallel columns of sentences: the…
Renders, Carry M; Halberstadt, Jutka; Frenkel, Carolien S; Rosenmöller, Paul; Seidell, Jacob C; Hirasing, Remy A
OBJECTIVE: The aim of this article is to share the Dutch experience of a nation-wide approach to reduce the prevalence of overweight and obesity. This is an practice example of national health policy. METHODS: The Ministry of Health facilitates three complementary initiatives to tackle overweight
Gameren-Oosterom, H.B.M. van; Dommelen, P. van; Schönbeck, Y.; Oudesluys-Murphy, A.; Wouwen, J.P. van; Buitendijk, S.E.
Prevalence of overweight in children is increasing, causing various health problems. This study aims to establish growth references for weight and to assess the prevalence rates of overweight and obesity in a nationwide sample of Dutch children with Down syndrome (DS), taking into account the
Bakker, R.H.C.; Groenewegen, P.P.; Jabaaij, L.; Meijer, W.; Sixma, H.; Veer, A. de
OBJECTIVE: to determine the effect of workload on 'burnout' having considered work capacity. DESIGN: cross-sectional study. SETTING: Dutch community midwives in independent practice. PARTICIPANTS: 200 Dutch community midwives. MEASUREMENTS: three-week diary recordings, a questionnaire on practice
Dekkers, A.; Raijmakers, N.; Galesloot, C.; Heide, A. van der
Introduction: The Dutch version of the Liverpool Care Pathway for the dying patient (LCP), Zorgpad Stervensfase, is a quality instrument for the care of dying people in the Netherlands. Since 2009 this pathway has been implemented nationwide in hospitals, nursing homes, hospices and homecare
Gameren-Oosterom, H.B.M.; Fekkes, M.; Wouwe, J.P. van; Detmar, S.B.; Oudesluys-Murphy, A.M.; Verkerk, P.H.
OBJECTIVE: To assess problem behavior in adolescents with Down syndrome and examine the association with sex and severity of intellectual disability. STUDY DESIGN: Cross-sectional data of a Dutch nationwide cohort of Down syndrome children aged 16-19 years were collected using a written parental
Engineering Services Ltd. has, in fulfillment of its contractual commitment to the Dutch Industrial Council for Energy and Environment Technology (IREM), investigated the broad capability of the Dutch industry in playing a major role in the supply of goods and services for the construction of nuclear plants in the Netherlands. The findings are summarized in this document. 5 tabs
Walma, E.P.; Visseren, F.L.; Jukema, J.W.; Kastelein, J.J.P.; Hoes, A.W.; Stalenhoef, A.F.H.
Until 2010, the Dutch ministry of Health, Welfare and Sport will fund a nationwide project to identify the approximately 40,000 patients with familial hypercholesterolaemia (FH) in the Netherlands. The Health Care Insurance Board will coordinate the project and safeguard its quality, while the
Q fever is a worldwide zoonosis caused by the bacterium Coxiella burnetii (C. burnetii). Small ruminants, in particular sheep and goats, have been associated with community Q fever outbreaks in other countries. Just prior to the Dutch Q fever epidemic, a nationwide survey indicated that only 2.4% of
Wouwe, J.P. van; Gameren-Oosterom, H.B.M. van; Verkerk, P.H.; Dommelen, P. van; Fekkes, M.
Object. To determine the level of mainstream education in a nationwide cohort of adolescents with Down Syndrome (DS), and to find characteristics related to mainstream or special school attendance. Method. Dutch children with DS born in 1992, 1993 or 1994, were assessed when 16–19 years old. Parents
Freimuth, Paul I.
The invention provides recombinant human CAR (coxsackievirus and adenovirus receptor) polypeptides which bind adenovirus. Specifically, polypeptides corresponding to adenovirus binding domain D1 and the entire extracellular domain of human CAR protein comprising D1 and D2 are provided. In another aspect, the invention provides nucleic acid sequences encoding these domains and expression vectors for producing the domains and bacterial cells containing such vectors. The invention also includes an isolated fusion protein comprised of the D1 polypeptide fused to a polypeptide which facilitates folding of D1 when expressed in bacteria. The functional D1 domain finds application in a therapeutic method for treating a patient infected with a CAR D1-binding virus, and also in a method for identifying an antiviral compound which interferes with viral attachment. The invention also provides a method for specifically targeting a cell for infection by a virus which binds to D1.
Velzel, Joost; Roovers, Jan Paul; van der Vaart, C. H.; Broekman, Bart; Vollebregt, Astrid; Hakvoort, Robert
Introduction and hypothesis: To identify practice variation in management of patients with a vaginal pessary for pelvic organ prolapse (POP). Methods: A nationwide survey was sent to all Dutch gynecologists with a special interest in urogynecology. Results: The response rate was 59 %. Of the
J. Velzel (Joost); J.P. Roovers (Jan Paul); C.H. Van der Vaart; B.M.W. Broekman (Bart); A. Vollebregt (Astrid); R. Hakvoort (Robert)
textabstractIntroduction and hypothesis: To identify practice variation in management of patients with a vaginal pessary for pelvic organ prolapse (POP). Methods: A nationwide survey was sent to all Dutch gynecologists with a special interest in urogynecology. Results: The response rate was 59 %. Of
Velzel, Joost; Roovers, Jan Paul; van der Vaart, C. H.; Broekman, Bart; Vollebregt, Astrid; Hakvoort, Robert
To identify practice variation in management of patients with a vaginal pessary for pelvic organ prolapse (POP). A nationwide survey was sent to all Dutch gynecologists with a special interest in urogynecology. The response rate was 59 %. Of the respondents, 13 % had a written protocol for pessary
den Hollander, Franciscus; Piersma, Kristien
Interview met Margriet Hidding, Birgit Lijmbach en Jeroen van Engen, medewerkers van het Talencentrum en de makers van de Massive Open Online Course (MOOC) Introduction to Dutch over het grote succes van deze cursus
In the series 'The Dutch Economy' the Dutch Statistical Office describes and analyzes annual developments in enterprises, households and governments, and with respect to employment and the environment. One of the subjects is 'Economy and Environment' with the sub-topics 'Resources and Energy', 'Emissions' and 'Environmental Taxes'. Furthermore, in articles on specific themes current economic issues are discussed. One of those themes has the title 'Share of renewable energy in the Netherlands is still small'. [nl
Marx, M.; Schuth, A.
A corpus called DutchParl is created which aims to contain all digitally available parliamentary documents written in the Dutch language. The first version of DutchParl contains documents from the parliaments of The Netherlands, Flanders and Belgium. The corpus is divided along three dimensions: per
The Dutch School in Geneva organizes Dutch education for children in the primary and secondary school. For the school year 2011-2012 the Dutch School in Geneva is looking for qualified part time teachers Dutch for the primary and secondary school. If you are interested, please send your application and curriculum vitae in Dutch by email to the NTC coordinator, Mrs. Anne Saeys (email@example.com). More info : www.ntcgeneve.info De vereniging Nederlandse Taal en Cultuur De Taalfontein, kortweg NTC Genève, is een oudervereniging, die tot doel heeft de Nederlandse taal en de Nederlandse en Vlaamse cultuur in de regio Genève te stimuleren. Dit geschiedt d.m.v. het organiseren van Nederlandse les voor leerlingen zowel in het basisonderwijs als het voortgezet onderwijs. Voor het volgende schooljaar zoekt NTC parttime docenten (M/V) vanaf 2 uur per week, zowel voor het Primair Onderwijs als voor het Voortgezet Onderwijs, met name voor de IB-opleiding. Voor het Primair Onderwijs dienen ge&...
Eric Schulte Nordholt
Full Text Available The Dutch 2011 Census tables were produced by combining existing register and sample survey data. Since the last census based on a complete enumeration was held in 1971, the willingness of the population to participace has fallen sharply. Statistics Netherlands no longer uses census questionnaires and has found an alternative in the register-based census, using only existing data. The register-based census is cheaper and more socially acceptable. The table results of the Netherlands are not only comparable with earlier Dutch censuses, but also with those of the other countries in the 2011 European Census Round.
Renneboog, L.D.R.; Spaenjers, C.
When-issued trading concerns transactions in securities that have not yet been issued. This type of trade often takes place in a so-called 'grey market', in which all contracts are conditional on the issuance of the security. In this paper, we investigate the Dutch grey market for when-issued shares
Renneboog, L.D.R.; Spaenjers, C.
When-issued trading concerns transactions in securities that have not yet been issued. This type of trade often takes place in a so-called ‘grey market’, in which all contracts are conditional on the issuance of the security. In this paper, we investigate the Dutch grey market for when-issued shares
Abbring, J.H.; Bronnenberg, B.J.J.A.M.; Gautier, P.A.; van Ours, J.C.
There is a tradition in the Netherlands to publish an annual ranking of economic and business researchers working in Dutch universities. The most recent such ranking, published in 2013, emphasizes research quantity over research quality. We propose an alternative ranking based on quality. Important
Postma, Dirkje S.; Weiss, Scott T.; van den Berge, Maarten; Kerstjens, Huib A. M.; Koppelman, Gerard H.
The Dutch hypothesis was first articulated in 1961, when many novel and advanced scientific techniques were not available, such as genomics techniques for pinpointing genes, gene expression, lipid and protein profiles, and the microbiome. In addition, computed tomographic scans and advanced analysis
Publication of the exhibition and symposium on water adaptive urban planning and architecture in Bangkok. The Urban Fine Dutch Tradition is a dynamic tradition of making urban designs using the parameters of the natural system – incorperating in an efficient way the hydrological cycle, the soil and
On the 1 October 1992 a change in the Dutch building legislation took effect: the revised Housing Act, the Building Decree and the technical documents related to this legislation came into force. This publication contains an English translation of the Building Decree. In order to give an idea of the
Nowadays, heritage is shifting towards a more structural approach, focusing on the urban landscape in which the intangible or the narrative of the place is used more often. The New Dutch Waterline is an example of this changing focus. This national transformation process (1999-now) led to high
OBJECTIVES OF THE THESIS
Heathlands in The Netherlands are vanishing due to the invasion of trees. The transition from heathland to woodland in Dutch heathlands may either proceed directly or is preceded by the development of an intermediate grass heath. These changes are due to natural
van Gulik, Thomas M.; Nimura, Yuji
An isolation policy was adopted in feudal Japan from 1639 to 1853 owing to the fear of foreign influence. During those 200 years of isolation, all foreigners were withheld from the country with the exception of the Dutch, who were permitted to establish a trading post on a small island in the Bay of
The ‘Risico- Inventarisatie- en Evaluatie-instrumenten’ is the name for the Dutch risk assessment (RA) tools. A RA tool can be used to perform a risk assessment including an evaluation of the identified risks. These tools were among the first online risk assessment tools developed in Europe. The
Rutten, R.J.; Hammerschlag, R.H.; Bettonvil, F.C.M.
The Dutch Open Telescope is now being installed at La Palma. It is intended for optical solar observations with high spatial resolution. Its open design aims to minimize disturbances of the local air ow and so re- duce the locally-generated component of the atmospheric seeing. This paper brie y
Francke, A.L.; Albers, G.; Bilsen, J.; Veer, A.J.E. de; Onwuteaka-Philipsen, B.D.
Objectives: To give insight into Dutch nursing staff’s attitudes and involvement regarding euthanasia. Methods: The sample was recruited from a nation-wide existent research panel of registered nurses and certified nursing assistants. Descriptive analyses and multivariate logistic regression
Dutch Minister of Education, Culture and Science R. Plasterk (third from left) in the ATLAS cavern with NIKHEF Director F. Linde, CERN Chief Scientific Officer J. Engelen, Ambassador J. van Eenennaam, ATLAS Collaboration Spokesperson P. Jenni, Mission Representative G. Vrielink and ATLAS Magnet Project Leader H. ten Kate.Minister of Education, Culture and Science from the Kingdom of the Netherlands, Ronald Plasterk, visited CERN on 25th October. With Jos Engelen, CERN Scientific Director, as his guide he visited Point 1 of the LHC tunnel and ATLAS, where Nikhef (the national institute for subatomic physics, a Dutch government and university collaboration) constructed all 96 of the largest muon drift chambers in the barrel as well as parts of the magnet system, the inner detector, the DAQ and triggering. Overall the Netherlands contribute 4.5% to the annual CERN budget and the minister’s visit celebrated the contributions of the 79 ...
Blokhuis, Erik; Advokaat, Bart; Schaefer, Wim
According to binding European Union agreements, the Netherlands has to cover at least 14% of its total energy use with renewable energy sources by 2020. However, the share of renewable energy in the Netherlands is small and hardly increasing. In 2010, renewable energy in the Netherlands accounted for only 3.8% of the national energy use, and has decreased with 0.4% compared to 2009. A cause of the stagnating renewable energy generation in the Netherlands is the absence of a nation-wide, clear and consistent long-term policy on the introduction of renewable energy. In order to overcome the current standstill in renewable energy adoption, several Dutch municipalities take the initiative and establish Local Energy Companies (LECs). However, to date, it is unclear which LEC type performs best. This research aims to compare the performance of existing LECs on three aspects: technology, finance, and organization. Furthermore, the performance of existing LECs is compared with theoretical reference LECs, in order to estimate efficiencies and opportunities for improvements. Finally, the influence of the recent changes in the Dutch subsidy scheme on LEC performance is examined. In order to achieve these aims, the benchmark method Data Envelopment Analysis is employed. - Highlights: ► Dutch Local Energy Companies (LECs) producing heat perform best in cost efficiency. ► Technical efficiency is highest in Dutch Local Energy Companies employing wind energy. ► Theoretical assumptions concerning LEC performance are not yet achieved in practice. ► The self supply model adds to the profitability of LECs, independent from subsidies. ► Recent changes in Dutch subsidy schemes add little to LECs’ financial performance.
Arends-Tóth, J.V.; van de Vijver, F.J.R.
The psychological component of immigration in the Netherlands was studied by comparing views on multiculturalism and acculturation orientation of Turkish migrants between Dutch majority (N=1565) and Turkish-Dutch minority (N=185) members. Multiculturalism was measured with an adaptation of the
This article argues that nostalgia for colonialism in the Netherlands, the so called tempo doeloe culture, is not a specifically postcolonial phenomenon caused by the collapse of the Dutch empire in Asia. In fact, nostalgia for the Dutch East Indies can be traced back to the nineteenth century, when
Postma, A; Van Leeuwen, EF; Gerritsen, EJA; Roord, JJ; De vries-Hospers, HG
The Dutch Childhood Leukemia Study Group celebrated its 20th anniversary by conducting a nationwide survey on supportive care for children with leukemia. Pediatricians were asked about daily practice and current perceptions with regard to supportive care. The results are discussed and compared to
Verdonk, Petra; Mans, Linda J. L.; Lagro-Janssen, Toine L. M.
Medical education has not taken on board the growing awareness of sex and gender differences. A nation-wide project to incorporate sex and gender in medical education aims to establish longitudinal gender and sex specific curricula in all Dutch medical schools that move beyond sex and gender differences in reproduction. A baseline assessment was…
Cheung, Ka-Chun; van den Bemt, Patricia M L A; Bouvy, Marcel L; Wensing, Michel; De Smet, Peter A G M
Many Dutch hospitals have established internal systems for reporting incidents. However, such internal systems do not allow learning from incidents that occur in other hospitals. Therefore a multicenter, information technology (IT) supported reporting system named central medication incidents registration (CMR) was developed. This article describes the architecture, implementation and current status of the CMR in The Netherlands and compare it with similar systems in other countries. Adequate IT is required to sufficiently support a multicenter reporting system. The CMR system consists of a website, a database, a web-based reporting form, an application to import reports generated in other reporting systems, an application to generate an overview of reported medication incidents, and a national warning system for healthcare providers. From the start of CMR 90 of all 93 (96.8%) hospitals and 872 of 1948 (44.8%) community pharmacies participated. Between March 2006 and March 2010 the CMR comprised 15,694 reports of incidents. In the period from March 2010 to March 2011, 1642 reports were submitted by community pharmacies in CMR and the hospitals submitted 2517 reports. CMR is similar to various systems in other countries, but it seems to use more IT applications. The CMR is developing into a nationwide reporting system of medication incidents in The Netherlands, in which hospitals, community pharmacies, mental healthcare organizations and general practitioners participate. The architecture of the system met the requirements of a nationwide reporting system across different healthcare providers.
Valois, J.C. de
Dutch radiodiagnostics viewed internationally. - A quantitative description of diagnostic radiology is given in terms of radiological density (the number of radiological examinations per 1000 inhibitants), consumptions of roentgen film and contrast media. The data concerning examinations were recorded by a yearly inquiry system addressing all Dutch radiologists. The consumption of film and contrast media were derived from the data banks of the industries. In comparing these data with the data for Western Europe, Japan and the United States it is remarkable that diagnostic radiology scores lowest in regard to density, film consumption and use of contrast media. Only in the use of 35 mm cinefilm (coronary angiography) is The Netherlands number 2 on the list preceded by the United States. As a consequence radiation exposure of the population caused by diagnostic radiology is low in The Netherlands. Although the technical condition of the equipment is good due to regular and preventive service the life-span of the radiological equipment is gradually increasing beyond the limits of the normal economic depreciation. Growing arrears are found in the application of new technology: ultrasound, computer tomography and magnetic resonance imaging. The substitution of high osmolar contrast media by low osmolar media is also laggin gbehind. (author). 10 refs.; 1 fig.; 4 tab
Hermans, Frans; Sloep, Peter
The Dutch overestimate their English speaking skills. Their pronunciation is not always convincing, and certain pronunciation mistakes are easily recognised as being typical for Dutch speakers of English. Although intelligibility cannot exist without adequate pronunciation, teaching English
Frans Hermans; Peter Sloep
The Dutch overestimate their English speaking skills. Their pronunciation is not always convincing and certain pronunciation mistakes are easily recognised as being typical for Dutch speakers of English. Although intelligibility cannot exist without adequate pronunciation, teaching English
Meulen, van der H.A.B.; Terluin, I.J.; Matser, I.A.
In this paper an analysis is made of the contribution of women to labour input and management on Dutch farms. We used a written survey among the participants of the Dutch Farm Accountancy Data Network (FADN), in-depth interviews and a group discussion with farm women. Over half of the women on Dutch
Asidigisianti Surya Patria
Dutch Batik is the referent of batik which is made by European-Indo woman industry. It can be identified by the European pattern which is a bouquet. This research is aimed to describe the correlation between the development of Dutch Batik with the role of the Dutch government and the Dutch merchant. The library research was used during analyzing the role of the government and the merchant using the Talcott Parsons’ functional structure theory. The batik Dutch companies were commercial oriente...
Many film scholars equate "film" with "moving images." But, along with sound and music, language is often no less important for a film’s interpretation. This paper discusses how comprehension of the original Dutch affords subtle aspects of meaning unavailable to viewers who have to rely exclusively
Chen, Shanli; Lin, Lin; Yuan, Cai
various pathological conditions and it is a robust biomarker for poor prognosis in various malignant conditions such as pulmonary adenocarcinoma. To facilitate crystallization, the two LU domains were excised from intact C4.4A by limited proteolysis, purified and crystallized by the sitting-drop vapour...... of C4.4A were excised by limited proteolysis and were crystallized using the sitting-drop vapour-diffusion method. The crystals diffracted to 2.7 Å resolution, giving good-quality data....
Kuleshova, E P; Zaleshin, A V; Sidorina, V V; Merzhanova, G Kh
The results obtained at the levels of single and network neuronal activity in the frontal and visual cortices of cats with different types of behavior revealed features of activity of these structures in normal conditions and after local introductions of antagonists of DI/D2 receptors (SCH23390 and raclopride) into the n. accumbens and frontal cortex. Under the influence of the antagonists, long-latency reactions were characterized by a significant increase in the average frequency of neuronal activity in the frontal cortex, whereas in the visual cortex the average frequency decreased as compared to norm. At the same time, the network activity of the same neurons in the frontal cortex did not change but weakened in the visual cortex, which was expressed in a reduction of the number of neuronal interactions within the visual cortex and between the neurons of the frontal and visual cortices. Normally, during the long-latency conditioned reactions, the average frequency of single neuronal activity and the rate of neuronal interactions in the structures under study were significantly higher as compared to the loss of conditioned reactions. Administration of the dopamine antagonists did not change these features. The results suggest different dopamine modulations of the network activity of the cortical zones under study during the conditioned performance, which is expressed in responsiveness of the cortical projection of a trigger signal (the visual cortex) and visual-frontal networks generated in the course of training.
Korkka-Niemi, K.; Sipilae, A.; Hatva, T.; Hiisvirta, L.; Lahti, K.; Alfthan, G.
The quality of water in 1 421 drinking-water wells was monitored in a nationwide well water study. Samples were taken once from all wells, and during three seasons from 421 wells. The wells were selected in such a way that me sample would be as representative as possible of the quality of the drinking-water in households' own wells in rural areas. The study comprised general water quality parameters, influence of sampling season, and factors related to the type, the condition and the pollution of the wells. In part of the well waters selenium, radioactivity and pesticides were determined. The effect of plumbing materials on the quality of water was also examined. (33 refs., 148 figs., 71 tabs.)
van Calmthout, Matijn
A new painting of Albert Einstein's field equation from his 1915 general theory of relativity was unveiled in a ceremony in November 2015 by the Dutch physicist Robbert Dijkgraaf, who is director of the Princeton Institute for Advanced Study in the US.
Bertens, C.; Snoei, J.
The 'Dutch Monitor Determinanten Bedrijfsprestaties in het MKB' (Determinants Company Performance Monitoring SMEs) has consulted almost 3.500 persons in SMEs on a number of questions, including on innovations. 40% of these persons perceive market opportunities for sustainable products, whereas only 25% of these businesses actually tries to capitalize on these opportunities. [nl
Dijk, L. van
The second Dutch National Survey of General Practice (DNSGP-2) has combined registration data on morbidity and prescription, making it possible to unravel diagnosis-specific prescription behaviour of general practitioners(GPs). Prescription rates for different disorders vary considerably, especially
Abrami, F.; Bijster, J.; Bitarafan, N.; Cao, Z.; Cui, Y.; Liu, Y.; Ruan, L.; Maas, M.; Mayr, R.; Rozenmuller, M.; Toriano, L.; Yoshitake, M.; Jauslin, D.
14 Project Documentations and Analysis of Dutch Architecture with Landscape Methods. MVRDV Villa VPRO, Powerhouse Company Villa 1, Herman Herzberger Coda Museum, NL Architects Basket Ba, SeARCH Posbank Pavillion, Wiel Arets Hedge House, OMA Kunsthal and Educatorium, Maaskant Johnson Wax, Diller &
H.J. de Vries (Henk); G.W.J. Hendrikse (George)
textabstractThe banks in the Dutch chipcard market initially agreed on one chipcard system. One system is attractive for companies as well as consumers. Companies, banks and retailers, prevent costs of duplication, while consumers enjoy the benefits of a widespread acceptance of one card and do not
Boer, de W.
This thesis is the result of a study on the production of nitrate in Dutch heathland soils. Most of the heathlands are located on acid, sandy soils. Therefore , it has dealt mainly with the occurrence, nature and mechanisms of nitrification in acid soils. In the Netherlands, the production
Wei, Y.; de Boer, S.J.; Stegwee, R.A.; Chen, Z.
Technology advances in ICT have permitted an increased flow of information across borders, and increasingly companies are moving to so-called virtual alliances. The business relationships between Dutch and Chinese companies are becoming closer by ways of outsourcing, new market development and so
Marselis, Randi Lorenz
This article examines memory politics in relation to radical actions of young Dutch-Moluccans, more specifically a train hijacking in 1977 at the village of De Punt in the Netherlands. The article examines how these historical events were remembered in the drama-documentary television film, De Punt...
At the end of 1980, a strategic decision was made by the Dutch banks and savings banks to commence the development of a Data Communications Infrastructure (DCI), to be used for a number of forthcoming interbank applications. It was agreed that this new data communications infrastructure should be
California Department of Resources — This dataset contains a nationwide build of the 2008 TIGER/Line datasets from the US Census Bureau downloaded in April 2009. The TIGER/Line Shapefiles are an extract...
de Heij, Hans A. M.
Since the introduction of a design methodology for Dutch banknotes, the quality of Dutch paper currency has improved in more than one way. The methodology is question provides for (i) a design policy, which helps fix clear objectives; (ii) design management, to ensure a smooth cooperation between the graphic designer, printer, papermaker an central bank, (iii) a program of requirements, a banknote development guideline for all parties involved. This systematic approach enables an objective selection of design proposals, including security features. Furthermore, the project manager obtains regular feedback from the public by conducting market surveys. Each new design of a Netherlands Guilder banknote issued by the Nederlandsche Bank of the past 50 years has been an improvement on its predecessor in terms of value recognition, security and durability.
Van Dieren, E.B. [Integraal Kankercentrum, Rotterdam (Netherlands); Nowak, P.J.C.M.; Van Soernsen de Koste, J.R.; Van Est, H.; Heijmen, B.J.M.; Levendag, P.C.
The variation in treatment portals for elective radiotherapy of the neck, and the three-dimensional dosimetric consequences of this variation was assessed. Therefore, 16 experienced radiation oncologists from all major head and neck cooperative groups in the Netherlands (n=11) were asked to define RT-portals on a lateral and/or AP simulation film, for (routine) elective neck irradiation for a T2 tumor of the mobile tongue and a T3 tumor of the supraglottic larynx. Treatment portals were compared and evaluated using a three-dimensional treatment planning system and CT data with contoured critical structures and target volume. The CT-defined clinical target volume was mutually agreed upon by ENT-surgeons and radiation oncologists. Large differences were seen in treated volume (a factor of five). In addition, due to the variation in the cranial boundary of the RT-portals, the estimated NTCP varied considerably (0-50%). Moreover, several of the RT-portals did not adequately cover the CT-defined target volume. Even amongst experienced head and neck radiation oncologists, little agreement was observed with respect to treatment technique and size of the treatment portals in case of elective neck irradiation. This results in a considerable variation in treated volume. As a consequence, a large difference exists in the anticipated probability of normal tissue complication, and possibly in tumor control probability. Therefore, a definition of target volume and, consequently, a standardization of elective neck portals in mandatory. This is even more important if the primary tumor and clinically node-negative neck are to be treated by 3D conformal RT using multiple CT-slices for target delineation and positioning of BEV blocks in order to spare the normal tissue function with maximum tumor control probability.
Maurits, E.E.M.; Veer, A.J.E. de; Groenewegen, P.P.; Francke, A.L.
The World Health Organization is calling for a fundamental change in healthcare services delivery, towards people‐centred and integrated health services. This includes providing integrated care around people′s needs that is effectively co‐ordinated across providers and co‐produced by professionals,
Elferink, M. A. G.; Siesling, S.; Lemmens, V. E. P. P.; Visser, O.; Rutten, H. J.; van Krieken, J. H. J. M.; Tollenaar, R. A. E. M.; Langendijk, J. A.
For adequate staging and subsequent accurate estimation of prognosis, a sufficient number of lymph nodes (LNs) has to be evaluated. This study aimed to identify factors associated with adequate nodal evaluation and to determine its relationship with survival. Data from all patients with stage I to
van Gerven-Haanpää, Minna Marja-Leena; Schubert, Klaus; de Villota, Paloma; Kuhlmann, Johanna
This chapter explores how the Dutch welfare system has evolved in the last decade(s). It shows that the economic crisis and the process of demographic change have put the Dutch welfare system to the test. The surmounting pressures from 2007 onwards have revealed structural problems of the Dutch
Duyvendak, J.W.; Scholten, P.
Dutch immigrant integration policies have often been labelled ‘multiculturalist’. This article empirically and conceptually challenges the idea of a Dutch multicultural model. First, it deconstructs the image that Dutch policies would have been driven by a single, coherent and consistent model, by
In 2002 the Dutch Euthanasia Act came into force. This Act is the result of a lengthy developmental process. It codifies the requirements that have evolved in case law and medical ethics since 1973. Empirical data indicate that the Dutch euthanasia practice is stabilising. Euthanasia and assisted suicide occur in 2.7% of all deaths. Now that the Act has been passed, the focus is on improving the quality of medical decision-making. From an international perspective, the Dutch legislation is exceptional. However, it appears that other countries and international organisations are considering euthanasia legislation as well. It remains to be seen how influential the Dutch model will prove to be.
van Wouwe, Jacobus P; van Gameren-Oosterom, Helma B M; Verkerk, Paul H; van Dommelen, Paula; Fekkes, Minne
To determine the level of mainstream education in a nationwide cohort of adolescents with Down Syndrome (DS), and to find characteristics related to mainstream or special school attendance. Dutch children with DS born in 1992, 1993 or 1994, were assessed when 16-19 years old. Parents scored school enrolment between the age of 4-18 years, general characteristics and the levels of intellectual disability using the Dutch Social Competence Rating Scale. Associations between disability and years in mainstream school were assessed by ordinal logistic regression, adjusting for sex and parental education. We collected data from 170 boys and 152 girls (response 63%); mean age 18.3 years (ranges 16.8-19.9). Intellectual disability was mostly moderate (43%). Most children (74%) entered mainstream education between 4 and 6 years of age. At 13 years 17% was in mainstream school and 7% stayed in up to 16 years. From the age of 8 years onwards the majority was in special education, while 6% never attended school. Girls were more often in mainstream school and stayed in longer. Level of disability was significantly associated with number of years in mainstream education. Three out of four Dutch children with DS entered mainstream primary education, however late entry and high dropout are common.
Asidigisianti Surya Patria
Full Text Available Dutch Batik is the referent of batik which is made by European-Indo woman industry. It can be identified by the European pattern which is a bouquet. This research is aimed to describe the correlation between the development of Dutch Batik with the role of the Dutch government and the Dutch merchant. The library research was used during analyzing the role of the government and the merchant using the Talcott Parsons’ functional structure theory. The batik Dutch companies were commercial oriented. It is different from real Javanese batik which had a purpose to be worn by themselves. Dutch Batik was the expression of the idea and behavior of the Dutch who lived in Indonesia. They expressed their western by using the patterns that were shown in their batik.
van Mullem, T.P.G.
Economic capital for Dutch retail banking booksA study on the effects of embedded options in Dutch retail banking books on interest rate risk and economic capitalIn dit proefschrift bestuderen we de effecten van embedded options in het retail bankboek op renterisico en economisch vermogen. In
Westert, G.P.; Berg, M.J. van den; Koolman, X.; Verkleij, H.
This is the second national report on the performance of the Dutch health care system. Its focus is on quality, access and costs in 2006/7. The Dutch Health Care Performance Report presents a broad picture based on 110 indicators. Where possible, comparisons in time and between countries are
Lückerath – Rovers, M.
The Dutch Female Board Index 2010 shows for the fourth year a survey of female representation on the Executive Boards and Supervisory Boards of 99 Dutch NVs listed on Euronext Amsterdam. The companies were classified by the percentage of women in their joint Executive Board and Supervisory Board.
Nejjari, W.; Gerritsen, M.; Haagen, M.J. van der; Korzilius, H.P.L.M.
This paper reports on a study into the reactions of ‘native’ speakers of British English to Dutch-English pronunciations in the onset of a telephone sales talk. In an experiment 144 highly educated British professionals who were either familiar or not familiar with Dutch-accented English responded
Luiijf, H.A.M.; Zielstra, A.
On December 1st, 2009, the fourth Dutch Process Control Security Event took place in Baarn, The Netherlands. The security event with the title ‘Manage IT!’ was organised by the Dutch National Infrastructure against Cybercrime (NICC). Mid of November, a group of over thirty people participated in the
Janssen, Lodevicus Johannes Henricus
There is reason for concern about the Dutch development cooperation. A survey of some aid evaluations of the Dutch Ministry of Foreign Affairs (MFA) showed that the aid results are limited and that the goals of the programs are not achieved. Management concerns using an organisation's resources to
Komen, M.; van Schooten, E.
In the Netherlands, ethnic minority boys are heavily overrepresented in prisons and secure judicial institutions for juveniles. In a sample of 324 juveniles of both native Dutch and ethnic minority origin who have come into contact with the Dutch criminal justice authorities, we compared the number
In 2002 the Dutch Euthanasia Act came into force. This Act is the result of a lengthy developmental process. It codifies the requirements that have evolved in case law and medical ethics since 1973. Empirical data indicate that the Dutch euthanasia practice is stabilising. Euthanasia and assisted
de Boer, Victor; Leinenga, Jurjen; Hoekstra, F.G.; van Rossum, Matthias; Mika, Peter; Tudorache, Tadia; Bernstein, Abraham
We present the Dutch Ships and Sailors Linked Data Cloud. This heterogeneous dataset brings together four curated datasets on Dutch Maritime history as five-star linked data. The individual datasets use separate datamodels, designed in close collaboration with maritime historical researchers. The
Knockaert, J.; Bakens, J.; Ettema, D.F.; Verhoef, E.
The Dutch road network is becoming increasingly congested. In late 2006, a group of companies, universities and government institutions established the Spitsmijden project. ‘Spitsmijden’ is the Dutch term for ‘avoiding the peak’. This joint initiative aimed to identify and assess a short-term
Lecture notes in DUTCH for course CIE5500, providing a detailed overview of Dutch and European water law concerning surface and groundwater, the North Sea and the Wadden Sea, water services, flood protection, spatial planning, nature protection, water management organizations (e.g. the water
Damoiseaux, Roger; McCartney, Margaret; Arie, Sophie
General practice is similar in the Netherlands and the UK yet it appeals far more to young Dutch doctors than to their British counterparts. In collaboration with the Dutch medical journal Nederlands Tijdschrift voor Geneeskunde, Roger Damoiseaux, professor of general practice, and Margaret
van der Elst, C.F.; Vermeulen, E.P.M.; De Cordt, Y.; Navez, E.J.
This Chapter in a comparative book on private limited liability companies starts with an illustration of the former success of the Dutch limited liability company (BV). Next it addresses the competitive European legal environment within which the Dutch BV has to operate. The study shows how the
Jijkoun, V.; Mishne, G.A.; de Rijke, M.; de Vries, A.P.
We report on the construction of the first-ever open domainquestion answering system for the Dutch language. In additionto providing experimental results based on the CLEF2003 QA test set for Dutch, we also identify a number ofkey natural language processing resources that are neededto further
Double Negation languages like Dutch and German still exhibit constructions, such as Dutch 'niemand niet' ‘nobody not’ or 'nooit geen' ‘nothing no’, that seem to have a Negative Concord reading. Since these constructions normally have an emphatic reading, they are called Emphatic Multiple Negative
Peters, Laura; Hilgendorf, Eric; Valerius, Brian
The modern Dutch sanctioning system started to develop as from 1886 with the introduction of the Wetboek van Strafrecht (Dutch Penal Code). With its primary focus on imprisonment and fines, this Code only included three principal penalties. However, it has undergone a statutory evolution, both in
From 1946 to 1949, the Netherlands fought a bloody decolonisation war with the newly proclaimed Republic of Indonesia. The official narrative of the Dutch government and military was that Dutch troops were restoring order and peace in a colony which the Republic had plunged into chaos and violence.
Klein Woolthuis, R.J.A.
This article discusses the strategies that sustainable entrepreneurs use to interact with their environment in the Dutch construction industry. The Dutch construction industry is under great pressure to move towards sustainability, and entrepreneurs are believed to be able to play a large role in
Klein Woolthuis, R.J.A.
This article discusses the strategies that sustainable entrepreneurs use to interact with their environment in the Dutch construction industry. The Dutch construction industry is under great pressure to move towards sustainability, and entrepreneurs are believed to be able to play a large role in
Gompel, M. van; Bosch, A.P.J. van den; Dijkstra, Anne; Dijkstra, A.; Boersma, P.; Brand, H.; Spoelstra, J.
In this paper we present a statistical machine translation (SMT) system for Frisian to Dutch and Dutch to Frisian. A parallel training corpus has been established, which has subsequently been used to automatically learn a phrase-based SMT model. The translation system is built around the open-source
van Maanen, Peter-Paul; Schokker, Jeroen; Harting, Ronald; de Bruijn, Renée
The Geological Survey of the Netherlands (GSN) systematically produces 3D stochastic geological models of the Dutch subsurface. These voxel models are regarded essential in answering subsurface-related questions on, for example, aggregate resource potential, groundwater flow, land subsidence hazard and the planning and realization of large-scale infrastructural works. GeoTOP is the most recent and detailed generation of 3D voxel models. This model describes 3D stratigraphical and lithological variability up to a depth of 50 m using voxels of 100 × 100 × 0.5 m. Currently, visually described borehole samples are the primary input of these large-scale 3D geological models, both when modeling architecture and composition. Although tens of thousands of cone penetration tests (CPTs) are performed each year, mainly in the reconnaissance phase of construction activities, these data are hardly used as geological model input. There are many reasons why it is of interest to utilize CPT data for geological and lithological modeling of the Dutch subsurface, such as: 1) CPTs are more abundant than borehole descriptions, 2) CPTs are cheaper and easier to gather, and 3) CPT data are more quantitative and uniform than visual sample descriptions. This study uses CPTs and the lithological descriptions of associated nearby undisturbed drilling cores collected by the GSN to establish a nationwide reference dataset for physical and chemical properties of the shallow subsurface. The 167 CPT-core pairs were collected at 160 locations situated in the North, West and South of the Netherlands. These locations were chosen to cover the full extent of geological units and lithological composition in the upper 30 to 40 m of the subsurface in these areas. The distance between the CPT location and associated borehole is small, varying between 0 and 30 m, with an average of 6 m. For each 2 cm CPT interval the data was automatically annotated with the lithoclass from the associated core using a
.... David Olson at 202-761-4922 or by email at david.b[email protected] or access the U.S. Army Corps of... Department of the Army, Corps of Engineers RIN 0710-AA71 Reissuance of Nationwide Permits AGENCY: Army Corps of Engineers, DoD. ACTION: Final notice; correction. SUMMARY: The U.S. Army Corps of Engineers...
Verrips, G.H.W.; Schuller, A.A.
Aim: To determine whether the subjective oral health (SOH) of the Dutch adult population was associated with clinical and demographic variables. Methods: A clinical examination was conducted in a sample of 1,018 people from the Dutch city of ‘s-Hertogenbosch. SOH was measured using the Dutch translation of the short form of the Oral Health Impact Profile (OHIP-NL14). Results: The average score on the OHIP-NL14 was 2.8 ± 5.9 and 51% of the respondents had a score of 0. Dental status was the mo...
Full Text Available An improved dutch roll approximation for hypersonic vehicle is presented. From the new approximations, the dutch roll frequency is shown to be a function of the stability axis yaw stability and the dutch roll damping is mainly effected by the roll damping ratio. In additional, an important parameter called roll-to-yaw ratio is obtained to describe the dutch roll mode. Solution shows that large-roll-to-yaw ratio is the generate character of hypersonic vehicle, which results the large error for the practical approximation. Predictions from the literal approximations derived in this paper are compared with actual numerical values for s example hypersonic vehicle, results show the approximations work well and the error is below 10 %.
Dutch Commerce and Chinese Merchants in Java describes the vanished commercial world of colonial Java. Alexander Claver shows the challenges of a demanding business environment by highlighting trade and finance mechanisms, and the relationships between the participants involved.
van den Dungen, F.A.M.; van Veenendaal, M.B.; Mulder, A.L.M.
The updated Dutch guidelines on Neonatal Resuscitation assimilate the latest evidence in neonatal resuscitation. Important changes with regard to the 2004 guidelines and controversial issues concerning neonatal resuscitation are reviewed, and recommendations for daily practice are provided and
Paauwe, Jaap, Ed.; Williams, Roger, Ed.
Includes "Seven Key Issues for Management Development" (Paauwe, Williams); "Typology of Management Development" (Jansen, van der Velde, Mul); "Management Development at Royal Dutch/Shell" (Mahieu); "Management Development in Unilever" (Reitsma); "International Co-ordination and Management…
Keywords: lexicography, onomasiology, dialect geography, language variation, phonology, historical linguistics, dictionary, regional dictionary, word atlas, cartography, general vocabulary, agrarian terminology, terminology of traditional crafts, dialect, traditional dialect, flemish, brabant dialect, limburg dialect, dutch, the ...
van Calmthout, Martijn
All 69 winners of the Spinoza prize - the highest award in Dutch science - have signed a petition against proposed reforms to the country's leading funding agency, the Netherlands Organisation for Scientific Research (NWO).
Gijsbert H.W. Verrips
Full Text Available Aim: To determine whether the subjective oral health (SOH of the Dutch adult population was associated with clinical and demographic variables. Methods: A clinical examination was conducted in a sample of 1,018 people from the Dutch city of ‘s-Hertogenbosch. SOH was measured using the Dutch translation of the short form of the Oral Health Impact Profile (OHIP-NL14. Results: The average score on the OHIP-NL14 was 2.8 ± 5.9 and 51% of the respondents had a score of 0. Dental status was the most important predictor of SOH. Conclusions: The SOH in the Dutch adult population was much better than in groups of adults in Australia, the United Kingdom and New Zealand. Nevertheless, there were important variations in SOH related to dental and socio-economic status.
Rutten, R.J.; Hammerschlag, R.H.; Bettonvil, F.C.M.
The Dutch Open Telescope represents a new solar telescope concept. Being open rather than evacuated, it leads the way to large- aperture high resolution telescopes. It is now being installed on La Palma.
Netherlands Food and Consumer Product Safety Authority
The amount of salt in many, especially commercially prepared, food is too high. Reducing salt intake can contribute positively to public health. A reduction in salt intake at a young age reduces the risk of hypertension and cardiovascular disease in later life. The salt intake of 2-6 year old Dutch children was estimated using the Dutch Food Consumption Survey, which was aimed at children in 2005/2006. The foods that contributed most to the total salt intake were determined.
Inge T A Peters
Full Text Available Breast cancer is one of the primary indications for cryopreservation and subsequent autotransplantation of ovarian tissue. The safety of this fertility preservation method remains questionable, as the presence of disseminated breast tumor cells cannot yet be excluded in the ovarian autografts. We explored the prevalence of ovarian metastases among young breast cancer patients and determined risk factors for the development of ovarian metastases.Using the nationwide database of the Dutch Pathology Registry (PALGA, we identified a cohort of 2648 women with primary invasive breast cancer at age 5 cm and/or inflammatory carcinoma, we recommend a cautious approach to ovarian tissue autotransplantation.
Celenk, O.; van de Vijver, F.J.R.
We studied mainstream couples in The Netherlands and Turkey as well as Turkish-Dutch immigrant couples to address cultural factors associated with marital satisfaction. A total of 13 Turkish (mainstream couples living in Turkey), 19 Turkish-Dutch (Turkish immigrant couples living in The
The Dutch Republic holds a marginal position in the debate on the transition from feudalism to capitalism, despite its significance in the early stage of the development of global capitalism. While the positions of those Marxists who did consider the Dutch case range from seeing it as the first
Huijgen, Tim; Holthuis, Paul; Trškan, Danijela
Oral history may enhance students’ historical content knowledge, historical reasoning competencies, and motivation to learn history. However, little is known regarding the role of oral history in Dutch history education. This study therefore explores the role of oral history in Dutch history
Janssen, M P M
This study took place within the framework of a general update of the average radiation dose for the Dutch population. It focuses on consumer products in which radionuclides have been intentionally incorporated and on radiation-emitting devices that can be supplied to members of the public without special surveillance. Eleven consumer products were studied in more detail. The radiation from these products determined 90% of the total collective dose due to consumer products in the Netherlands in 1988. Individual and collective doses are presented here for each product. The total collective dose has decreased from 130 personSv in 1988 to 4.6 personSv at present. This reduction was attributed to: a decrease in the number of radioactive products (gas mantles), lower estimates of the number of radioactive products present in the Netherlands thanks to new information (camera lenses, smoke detectors containing Ra-226), replacement of radioactive by non-radioactive products (gas mantles, dental protheses), and a lowe...
Celenk, Ozgur; van de Vijver, Fons J R
We studied mainstream couples in The Netherlands and Turkey as well as Turkish-Dutch immigrant couples to address cultural factors associated with marital satisfaction. A total of 13 Turkish (mainstream couples living in Turkey), 19 Turkish-Dutch (Turkish immigrant couples living in The Netherlands), and 17 Dutch (mainstream couples living in The Netherlands) married dyads (total of 98 individuals) were independently interviewed about positive and negative characteristics of marriages, determinants of general marital satisfaction and dissatisfaction, spousal communication, marital conflict, and marital roles. Multivariate tests revealed ethnic group differences on all marriage-related domains except the conflict resolution strategies. However, univariate analyses showed differences in few themes within domains; main differences were assessed between the Turkish/Turkish-Dutch (who put more emphasis on children and economical aspects) and Dutch couples (who put more emphasis on behavior, and personality of the spouse, reciprocity, emotional sharing, and psychological roles). Turkish-Dutch couples were more similar to Turkish than to Dutch couples. Results were discussed in light of the socioeconomic development and cultural value theories, which are believed to provide a useful framework for understanding the role of culture in marital satisfaction.
Verschoor, W.F.C.; Rubbaniy, G.; Lelyveld van, I.P.P.
Using a panel data set of more than 600 Dutch pension funds (PFs) between 1992 and 2006, we investigate asset allocation behavior of Dutch PFs across multiple asset classes. We find that domestic investments, also known as home bias, in portfolio choices of Dutch institutional investors have fallen.
Canisius, S.V.M.; van den Bosch, A.; Decadt, B.; Hoste, V.; De Pauw, G.
We describe the development of a Dutch memory-based shallow parser. The availability of large treebanks for Dutch, such as the one provided by the Spoken Dutch Corpus, allows memory-based learners to be trained on examples of shallow parsing taken from the treebank, and act as a shallow parser after
Hermes, Niels; Hooghiemstra, Reggy; van Veen, Kees
Eumedion is a Dutch foundation representing the interests of Dutch and foreign institutional investors with investments in Dutch listed companies. In particular, it represents the interests of these participants in the field of corporate governance and sustainability. The foundation was established
Ordelman, Roeland J.F.; de Jong, Franciska M.G.; van Hessen, Adrianus J.; Hondorp, G.H.W.
This contribution describes the Twente News Corpus (TwNC), a multifaceted corpus for Dutch that is being deployed in a number of NLP research projects among which tracks within the Dutch national research programme MultimediaN, the NWO programme CATCH, and the Dutch-Flemish programme STEVIN. The
Newbery, D.; Von der Fehr, N.H.; Van Damme, E.
Industry concerns over perceived reductions in the liquidity of the Dutch wholesale electricity market led the DTe to ask the Market Surveillance Committee (MSC) to examine recent developments. This report starts with a generic examination of wholesale power markets and liquidity and its measurement. An overview of the Dutch wholesale electricity market and its constituent segments follows together with a summary of events and opinions connected to liquidity that have been reported in the trade press. Sources of information on market liquidity are then reviewed. Participation in the market is analysed before examining each market segment and this analysis and the earlier sections are then drawn together in conclusions and recommendations
The Royal Dutch Petroleum Company has no operations of its own and virtually the whole of its income derives from its 60% interest in the companies known collectively as the Royal Dutch/Shell Group of Companies; the other 40% is owned by the Shell Transport and Trading Company, p.l.c. The company is engaged in the oil, natural gas, chemicals, coal and metals businesses throughout the world. The annual report summarises the year's results and analyses earnings in each industry segment. Financial statements for the year ended 31 December 1992 are presented. The Group companies' estimated net quantities of crude oil, natural gas and coal are given
Lückerath – Rovers, M.
The Dutch ‘Female Board Index 2009’ provides for the third year an overview of female representation on the Executive Boards and Supervisory Boards of 107 Dutch NV companies listed on Euronext Amsterdam. The study showed that in September 2009, 38 listed Dutch companies have one or more women on
Bevelander, P.; Groeneveld, S.M.
This study analyses female native Dutch and ethnic minority employment patterns in the Dutch labour market. Focusing on life-course employment patterns, it aims to find out if native Dutch and ethnic minority women in the Netherlands have undergone a transition towards more labour market
Investigated what abilities and objectives can be measured on practical tests. Results suggest that these tests be composed of separate parts which measure the ability to perform an experiment and the ability to interpret and analyze an experiment. A brief description of the Dutch school system is included. (JN)
Stol, W.PH.; Kaspersen, H.W.K.; Kerstens, J.; Leukfeldt, E.R.; Lodder, A.R.
Following the example of Norway and other European Countries, such as Sweden and Denmark, in April 2007 the Dutch government started filtering and blocking web pages with child pornographic content. In this paper we present a research into the technological, legal and practical possibilities of this
M. Snelder; A.P.M. Wagelmans (Albert); J.M. Schrijver; H.J. van Zuylen (Henk); L.H. Immers (Lambertus)
textabstractThe Dutch national road network has been developed over several decades. In the past, roads were constructed according to the then current spatial and transportation planning philosophies. Because the existing road network is a result of a long process of successive developments, the
Goedegebuure, Leo C. J.; Westerheijden, Don F.
A discussion of recent changes in Dutch higher education provides an overview of the educational system and recent retrenchment and restructuring efforts, and formulates a framework for policy analysis that treats the system as a policy network. Basic processes influencing the outcomes of government policies promoting change are examined.…
Lückerath – Rovers, M.
This report gives an overview of the presence of women in the Executive Board and Supervisory Board (together: 'the Board') of Dutch listed companies per September 2009. The companies have been ranked by the percentage women in the Board. A difference analysis has been made at personal level
After many years of persistent telescope design and telescope construction, R.H. Hammerschlag has installed his Dutch Open Telescope (DOT) on La Palma. I brie y review its history and design. The future of optical solar physics at Utrecht hinges on a recently-funded three- year DOT science
Rutten, R.J.; Hammerschlag, R.H.; Sütterlin, P.; Bettonvil, F.C.M.
Superb movies from the Dutch Open Telescope (DOT) on La Palma have proven the validity of the open concept of this innovative telescope for high-resolution imaging of the solar atmosphere. A five- camera speckle-burst registration system is being installed that should permit consistent and
van der Roest, Jan Willem; Vermeulen, Jeroen; van Bottenburg, Maarten
This article deals with the tension between the association logic and the market logic that appears in the domain of voluntary sport clubs (VSCs). We present a qualitative analysis of sport policy texts of fifteen Dutch national sport organizations (NSOs) and the national umbrella organization to
van der Roest, Jan Willem; Vermeulen, Jeroen; van Bottenburg, Maarten; LS Sportontw. & Managing Social Issues; UU LEG Research USG Public Matters Managing Social Issues; LS Management van Cultuur en Zingeving
This article deals with the tension between the association logic and the market logic that appears in the domain of voluntary sport clubs (VSCs). We present a qualitative analysis of sport policy texts of fifteen Dutch national sport organizations (NSOs) and the national umbrella organization to
Winkels, R.; de Ruyter, J.; Kroese, H.
In this paper we present the results of two studies to see whether the analysis of the network of citations between cases can be used as an indication of the relevance and authority in the Dutch legal system. Fowler e.a. have shown such results for the US common law system, but given the different
Bouma, G.J.; Hendriks, P.
Dutch allows for variation as to whether the first position in the sentence is occupied by the subject or by some other constituent, such as the direct object. In particular situations, however, this commonly observed variation in word order is ‘frozen’ and only the subject appears in first
Kleefstra, Nanne; Landman, Gijsw. D.; Van Hateren, Kornelis J. J.; Meulepas, Marianne; Romeijnders, Arnold; Rutten, Guy E. H.; Klomp, Maarten; Houweling, Sebastiaan T.; Bilo, Henk J. G.
Background: Recent decades have seen a constant upward projection in the prevalence of diabetes. Attempts to estimate diabetes prevalence rates based on relatively small population samples quite often result in underestimation. The aim of the present study was to investigate whether the Dutch
Annema, J.A.; De Wee, G.P.
In this paper eight stories are told about Dutch passenger transport history. The first story is from 1814 about building the first national paved road network suitable for stagecoaches; the last is from 1997 and is about the decision to construct a high speed rail link from Amsterdam to the
In this address, important aspects of the Dutch system of managed competition are discussed from the economic perspective, highlighting both its merits and the major challenges posed by the development of this system. Reasons for government intervention in healthcare markets are provided, and the
Schippers, Gerard M.; Schramade, Mark; Walburg, Jan A.
The Dutch substance abuse treatment system is in the middle of a major reorganization. The goal is to improve outcomes by redesigning all major primary treatment processes and by implementing a system of regular monitoring and feedback of clinical outcome data. The new program includes implementing
de Leede, Jan; Looise, Jan C.; van Riemsdijk, Maarten
From a very centralistic and collectivistic tradition after World War Two, Dutch employment relations now show a trend towards radical decentralisation and individualisation. What might be the consequences of this trend for labour relations? Do developments still fit within a movement towards
Korenromp, I.H.; Meeus, M.; Bleijenberg, G.
Chronic fatigue is a frequent but unspecific characteristic of many diseases. However, a clear definition of 'chronic fatigue' is still lacking. The Flemish-Dutch Research Group - Chronic Fatigue (VNO-CHROVER) has taken the opportunity to formulate such a definition that can be widely applied. This
Gradus, R.H.J.M.; Dijkgraaf, E.
We analyse the Dutch waste-collection market for 1998-2005. We show that municipalities with unit-based pricing (UBP) or waste collection by private companies have lower costs. However, this cost advantage decreases over time as competition decreases, because of the introduction of the
Lopes Cardozo, M.T.A.; Novelli, M.
This report focuses on developments in Dutch aid to education in conflict affected areas in the last decade, with a focus on the period 2007‐2010, when ex‐Minister for International Development, Koenders was in office. In this relatively brief time frame, Koenders prioritised development cooperation
Janssen MPM; Vries L de; Phaff JC; Graaf ER van der; Blaauboer RO; Stoop P; Lembrechts J; TNO-Bouw; KVI; LSO
Radon concentrations and external exposure by nuclides of the U-238 decay chain were quantified for a typical Dutch townhouse using a series of interconnected computer models. The effect is studied of changes in parameter values which have simulated changes in building practices over the past
van Oers, M.H.M.; Strous, L.; Berndsen, R.J.; Butts, J.; Shenoi, S.
This paper presents a case study of critical infrastructure protection in the Dutch financial sector. The organizational structures are examined to discern the roles and functions that facilitate public-private cooperation. An assessment of the organizational structures is provided along with a
Ierland, van E.C.
On initiative of the Dutch Parliament a scenario study took place on economics, energy and the environment, to analyse the need of building additional nuclear power plants in the Netherlands in the coming decades. Characteristic for the study is the application of empirical models that describe the
Barendregt, H.P.; Eekelen, M.C.J.D.; Hartel, Pieter H.; Hertzberger, L.O.; Plasmeijer, M.J.; Vree, W.G.
In November 1984 three research groups at the universities of Amsterdam, Nijmegen and Utrecht started a cooperative project sponsored by the Dutch Ministry of Science and Education (Science Council). The first phase lasting until the end of 1987 is a pilot study and has as aim to answer the
Huang, Xiaohong; Mahieu, R.
This paper studies the investment performance of pension funds with a focus on their ability in implementing their intended investment strategy. We use a sample of Dutch industry-wide pension funds, which are obliged by law to report their investment performance according to the so-called z-score.
Klis, van der Jolande
Of all the composers produced by the Netherlands, only two have achieved world renown: Jan Pieterszoon Sweelinck in the early seventeenth century and Louis Andriessen today. Nonetheless, so much more Dutch music is worthy of attention. For the first time ever, four centuries of composition in the
The Dutch educational system is highly stratified from secondary education onwards3, and this also applies to MBO. Each MBO course can be followed in two different learning pathways, called the vocationally educating learning pathway (beroepsopleidende leerweg: BOL) and the vocationally guiding
Various clause types in Dutch and German are at least temporarily ambiguous with respect to the order of subject and object. A number of previous studies regarding the processing of such subject-object ambiguities have reported a preference for a subject-object interpretation. This order preference
Bakker, D.C E; de Baar, H.J.W.; de Wilde, H.P.J.
The role of shelf seas in global carbon cycling is poorly understood. The dissolved inorganic carbon system and air-sea exchange of carbon dioxide (CO2) are described for the Dutch coastal zone in September 1993. The inorganic carbon chemistry was affected by tidal mixing, wind speed, wind
Groenewold, Rimke; Bastiaanse, Roelien; Huiskes, Mike
Background: Previous studies have shown that individuals with aphasia are usually able to produce direct reported speech constructions. So far these studies have mainly been conducted in English. The results show that direct speech is beneficial for aphasic speakers for various reasons. In Dutch the
Kuiper, H.; de Jongh, B. M.; Nauta, A. P.; Houweling, H.; Wiessing, L. G.; van Charante, A. W.; Spanjaard, L.
Serum samples from 127 Dutch forestry workers and 127 matched controls were tested for antibodies against Borrelia burgdorferi in an indirect immunofluorescence assay (IFA). Those of the forestry workers were also tested by Western blotting. The forestry workers were examined clinically for evidence
Hildebrandt, V.H.; Bongers, P.M.; Dijk, F.J. van; Kempers, H.C.G.; Dul, J.
The article describes the Dutch Musculoskeletal Questionnaire (DMQ) for the analysis of musculoskeletal workload and associated potential hazardous working conditions as well as musculoskeletal symptoms in worker populations. Its qualities are explored using a database of 1,575 workers in various
Bogers, R.P.; Leeuwen, F.E. van; Grievink, L.; Schouten, L.J.; Kiemeney, L.A.L.M.; Schram-Bijkerk, D.
Suspicion has been raised about an increased cancer risk among Balkan veterans because of alleged exposure to depleted uranium. The authors conducted a historical cohort study to examine cancer incidence among Dutch Balkan veterans. Male military personnel (n=18,175, median follow-up 11 years) of
Nijdam, Mirjam J.; Gersons, Berthold P. R.; Olff, Miranda
The psychosocial effects of terrorist threat and close protection have never been studied systematically in political leaders. We conducted a study among 12 Dutch politicians and their partners who were living under terrorist threat and close protection in the aftermath of two political murders.
M.J. Kemman (Max); M. Kleppe (Martijn); B. Nieman; H.J.G. Beunders (Henri)
textabstractWith an ever-growing supply of online sources, information to produce news stories seems to be one mouse click away. But in what way do Dutch journalists actually use computer-aided research tools? This article provides an inventory of the ways journalists use digital (re)sources and
Buurma, J.S.; Smit, P.X.
Dutch greenhouse horticulture has an innovation and development programme called 'Kas als Energiebron' (Greenhouse as Energy Producer). The objective of this programme is reducing the carbon footprint and improving the energy efficiency of greenhouse horticulture, and developing a climate neutral
Koning, Ruud H.
In this paper, we estimate an ordered probit model for soccer results in The Netherlands. The result of a game is assumed to be determined by home advantage and quality differences of the opposing teams. The parameters of the model are used to assess whether competitive balance in Dutch professional
This article compares Dutch rural and non-rural adolescents’ delinquent behavior and examines two social correlates of rural delinquency: communal social control and traditional rural culture. The analyses are based on cross-sectional data, containing 3,797 participants aged 13–18 (48.7% females).
William N., Jr. Cannon; David P. Worley
Municipal programs to suppress Dutch elm disease have had highly variable results. Performance as measured by tree mortality was unrelated to control strategies. Costs for control programs were 37 to 76 percent less than costs without control programs in the 15-year time-span of the study. Only those municipalities that conducted a high-performance program could be...
This paper considers the degree of competitiveness of the Dutch consumer credit market. We use the well-known Bresnahan-Lau method that estimates a structural model consisting of a demand relation and a supply relation, based on aggregate data. The level of competition is derived from the estimated
This paper considers the degree of competitiveness of the Dutch consumer credit market. We use the well-known I Bresnahan-Lau method that estimates it structural model consisting of a demand relation and a supply relation, based on aggregate data. The level of compelition is derived from the
Lohuis-Weber, Heleen; Zonneveld, Wim
Presents the results of an investigation into the acquisition of syllable structure and stress by a preschool Dutch child. Shows how the structure of the child's output approaches the adult models in stages and discusses a phenomenon called "mutation," in which all continuants are consistently replaced with "n-" in onsets. (51…
Klootwijk, C.W.; Middelaar, van C.E.; Berentsen, P.B.M.; Boer, de I.J.M.
The abolition of the Dutch milk quota system has been accompanied by the introduction of a new manure policy to limit phosphate production (i.e., excretion via manure) on expanding dairy farms. The objective of this study was to evaluate the effect of these recent policy changes on the farm
van Dijk, KN; de Vries, CS; van den Berg, PB; Brouwers, JRBJ; de Jong-van den Berg, LTW
Objective: To quantify and evaluate drug utilisation in a sample of Dutch nursing homes. Methods: A retrospective analysis of computerised medication data of 2355 residents aged 65 years and over from six nursing homes in the Netherlands was performed. For each therapeutic drug group, the number of
F.T. Schut (Erik)
textabstractFor more than two decades, Dutch health policy has been marked by a search for a suitable market order in health care. Suitable in the sense of maintaining universal access, containing the growth of health care expenditure and improving the technical and allocative efficiency of
Flexible benefit plans give employees a greater say over the composition of their benefits than traditional Dutch benefit plans. These arrangements developed in a time of further individualisation, increasing flexibility in the workplace, and a tight labour market in the Netherlands. By giving
Zeiler, W.; Quanjel, E.M.C.J.; Borsboom, W.A.
Within the present context of the Dutch Sustainable Building Practice it is hard for the different involved building design disciplines to give a good answer to sustainability. Especially this is the case for the application solar energy either in passive or active form. As traditional methods did
Mol, Nico P.; de Kruijf, J.A.M.
This article investigates how and to what extent performance indicators in Dutch central government are actually embedded in performance management. In a case study encompassing 12 government organizations, the relevance of the indicators presented is analysed in three stages: (1) with respect to
Being missionary, being human is a must, especially for those with an interest in missiology. It not only provides a fresh perspective on the missionary history of the Dutch Reformed Church (DRC) in South Africa, it also provides a clear description of the interactive relationship between context and mission. The author is a ...
Jijkoun, V.; Mishne, G.A.; de Rijke, M.
We describe a framework for offline extraction of certain types of information from a document collection, and discuss its usage for answering factoid questions. We implemented this approach as a part of the Dutch Question Answering System developed at the University of Amsterdam. The evaluation of
Inequalities have been exacerbating in the Netherlands since the economic crisis hit ground in 2008, with poverty increasing substantially. The amount of the Dutch population living under the poverty line increased from 7,4 % in 2010 to 10,3 % in 2013. Different types of household are affected:
Smeulders, A.W.M.; van Gemert, J.C.; Geusebroek, J.M.; Snoek, C.G.M.; Worring, M.
Pictures have always been a prime carrier of Dutch culture. But pictures take a new form. We live in times of broad- and narrowcasting through Internet, of passive and active viewers, of direct or delayed broadcast, and of digital pictures being delivered in the museum or at home. At the same time,
In this article an agricultural household model is developed in which production and consumption decisions are non-separable. On the basis of this model the importance of coupling production and consumption decisions is investigated for the Dutch dairy sector both before and after the introduction
Twenty-seven Dutch companies will present the state of the art of their technological developments at the industrial exhibition Holland @ CERN from 8 to 11 November. The exhibition is designed to help strengthen the ties between fundamental science and Dutch industry. The exhibition, supported by the Dutch Ministry of Economic Affairs and organised by the Netherlands National Institute for Subatomic Physics (Nikhef), in cooperation with the Foundation for Fundamental Research on Matter (FOM), the FOM Institute for Plasma Physics Rijnhuizen, and Dutch Scientific, an association of manufacturers of scientific equipment, will be held in the Main Building from 8 to11 November. “The last Holland @ CERN exhibition took place fifteen years ago”, says Robert Klöpping from Nikhef, Dutch Industrial Liaison Officer for CERN and Purchasing Advisor for Grenoble ESRF. “This kind of event is very important for Dutch industry as it allows us to show what Dutch companies c...
The purpose of the study is to investigate similarities and differences in the use of politeness strategies in formulating requests between Dutch learners of English, native speakers of Dutch and native speakers of English. A second objective was to gain more insights into the influence of
Conclusion: This is the first nationwide birth weight norm for twins in Taiwan, which is particularly useful for investigation into the predictors and outcomes of altered fetal growth through twin studies in the Taiwanese population.
U.S. Department of Health & Human Services — The Nationwide Readmissions Database (NRD) is a unique and powerful database designed to support various types of analyses of national readmission rates for all...
U.S. Department of Health & Human Services — The Nationwide Emergency Department Sample (NEDS) was created to enable analyses of emergency department (ED) utilization patterns and support public health...
Buurgaard Nielsen, J.; Pols, D.; Van Gelder, J.W.; Denie, S.; Scheire, C.
This report is the first comparison of the climate change performance of Dutch banks that analyses the actual investments of these banks. It reviews a substantial share of each bank's portfolio, according to three criteria: how much they invest in the main cause of climate change, fossil fuels; how much they invest in the main alternative to fossil fuels, renewable energy; the bank's plans and policies to limit their contribution to climate change
This paper considers the degree of competitiveness of the Dutch consumer credit market. We use the well-known I Bresnahan-Lau method that estimates it structural model consisting of a demand relation and a supply relation, based on aggregate data. The level of compelition is derived from the estimated conjectural variation elasticity. Our empirical results show that there is no evidence of market power.
Berg, Alan; Scheffel, Maren; Drachsler, Hendrik; Ternier, Stefaan; Specht, Marcus
We present the collected experiences since 2012 of the Dutch Special Interest Group (SIG) for Learning Analytics in the application of the xAPI standard. We have been experimenting and exchanging best practices around the application of xAPI in various contexts. The practices include di fferent design patterns centered around Learning Record Stores. We present three projects that apply xAPI in very diff erent ways and publish a consistent set of xAPI recipes.
Van Diest, Ilse; Smits, Dirk; Decremer, Davina; Maes, Lori; Claes, Laurence
Fear of suffocation and fear of restriction are thought to underlie claustrophobia and can be assessed with the Claustrophobia Questionnaire (CLQ; Radomsky et al., 2001). A first study tested the psychometric properties of a Dutch version of the CLQ. Students (N=363) completed a Dutch translation of the CLQ and a set of other questionnaires assessing other specific fears, anxiety or depression. Results confirmed the two-factor structure and showed that the Dutch version of the CLQ has good psychometric properties. A second study tested the predictive validity of the Dutch CLQ. Participants (N=23) were exposed each to nine claustrophobic situations with elements of suffocation, restriction or both. The Dutch CLQ was found to be a significant predictor of fear and respiratory reactivity during claustrophobic exposure. It can be concluded that the Dutch version of the CLQ is a reliable and valid instrument to assess claustrophobic fear. Copyright 2010 Elsevier Ltd. All rights reserved.
Chynoweth, E.; Schoenmakers, J.
Dutch chemical producers have negotiated a long-term agreement with government ministries to reduce emissions of a wide range of chemicals. Industry association Vereniging van de Nederlandse Chemische Industrie (VNCI; Leidschendam) says implementing the commitment will cost companies Dfl 10 billion ($5.4 billion) between 1993 and 2000. VNCI technical director Wim Quik welcomes the accord, which he describes as a management contract, saying, Rather than have legislation, there is a certain adjustment available. Peter Santen, managing director of midsized chemicals player Cindu Chemicals (Uithoorn, the Netherlands) voices some concern about the details of the accord, but adds, we are flexible in trying to agree with the contents of the covenant [it] is better than having new rules from law. The Dutch government, traditionally eager for consensus, has struck a number of such deals with Dutch industries - including packaging, metal, and tire - to reduce emissions and set up environmental management programs. The effort is based on the government's National Environmental Policy Plans - NMP and NMP Plus. Targets for emissions reduction by the chemical industry were provided by a government-funded environmental research institute
Kitamura, Tetsuhisa; Iwami, Taku; Kawamura, Takashi; Nagao, Ken; Tanaka, Hideharu; Hiraide, Atsushi
It is unclear whether dissemination of automated external defibrillators (AEDs) in public places can improve the rate of survival among patients who have had an out-of-hospital cardiac arrest. From January 1, 2005, through December 31, 2007, we conducted a prospective, population-based, observational study involving consecutive patients across Japan who had an out-of-hospital cardiac arrest and in whom resuscitation was attempted by emergency responders. We evaluated the effect of nationwide dissemination of public-access AEDs on the rate of survival after an out-of-hospital cardiac arrest. The primary outcome measure was the 1-month rate of survival with minimal neurologic impairment. A multivariate logistic-regression analysis was performed to assess factors associated with a good neurologic outcome. A total of 312,319 adults who had an out-of-hospital cardiac arrest were included in the study; 12,631 of these patients had ventricular fibrillation and had an arrest that was of cardiac origin and that was witnessed by bystanders. In 462 of these patients (3.7%), shocks were administered by laypersons with the use of public-access AEDs, and the proportion increased, from 1.2% to 6.2%, as the number of public-access AEDs increased (Ppublic-access AEDs, 31.6% were alive at 1 month with minimal neurologic impairment. Early defibrillation, regardless of the type of provider (bystander or emergency-medical-services personnel), was associated with a good neurologic outcome after a cardiac arrest with ventricular fibrillation (adjusted odds ratio per 1-minute increase in the time to administration of shock, 0.91; 95% confidence interval, 0.89 to 0.92; Ppublic-access AEDs increased from fewer than 1 per square kilometer of inhabited area to 4 or more. Nationwide dissemination of public-access AEDs in Japan resulted in earlier administration of shocks by laypersons and in an increase in the 1-month rate of survival with minimal neurologic impairment after an out
Lückerath – Rovers, M.
The Dutch ‘Female Board Index 2008’ provides for the second year an overview of female representation on the Board of Directors and Supervisory Boards of 113 Dutch NV companies listed on Euronext Amsterdam. The companies are ranked according to the percentage of women present on their combined Board of Directors and Supervisory Boards. The Dutch ‘Female Board Index’ also analyses the differences between male and female executive directors and supervisors ('non-executive directors') and betwee...
K.C. Cheung (Ka Chun); P.M.L.A. van den Bemt (Patricia); M.L. Bouvy (Marcel); M.E. Wensing (Michel); P.A. de Smet (Peter)
textabstractObjective Many Dutch hospitals have established internal systems for reporting incidents. However, such internal systems do not allow learning from incidents that occur in other hospitals. Therefore a multicenter, information technology (IT) supported reporting system named central
Cheung, K.C.; Bemt, P.M. van den; Bouvy, M.L.; Wensing, M.J.P.; Smet, P.A.G.M. de
Objective Many Dutch hospitals have established internal systems for reporting incidents. However, such internal systems do not allow learning from incidents that occur in other hospitals. Therefore a multicenter, information technology (IT) supported reporting system named central medication
Wagenaar, Frank-Christiaan; Löwik, Claudia A M; Stevens, Martin; Bulstra, Sjoerd K; Pronk, Yvette; van den Akker-Scheek, Inge; Wouthuyzen-Bakker, Marjan; Nelissen, Rob G H H; Poolman, Rudolf W; van der Weegen, Walter; Jutte, Paul C
Background: Persistent wound leakage after joint arthroplasty is a scantily investigated topic, despite the claimed relation with a higher risk of periprosthetic joint infection. This results in a lack of evidence-based clinical guidelines for the diagnosis and treatment of persistent wound leakage
Korfker, D.G.; Reis, R.; Rijnders, M.E.B.; Meijer-van Asperen, S.; Read, L.; Sanjuan, M.; Herschderfer, K.; Buitendijk, S.E.
Objectives To determine the prevalence of female genital mutilation (FGM) in women giving birth in 2008 in the Netherlands. Method A retrospective questionnaire study was conducted. The study covered all 513 midwifery practices in the Netherlands. The data were analysed with SPSS 17.0. Results The
Ang, C.W.; Brandenburg, A.H.; Van Burgel, Nathalie D.; Bijlmer, Henk A; Herremans, T.; Stelma, Foekje F.; Verduyn Lunel, FM|info:eu-repo/dai/nl/345898028; van Dam, Alje P
Numerous tests for the detection of antibodies against Borrelia burgdorferi are commercially available. Manufacturer-derived data invariably report a high sensitivity and specificity, but comparative studies demonstrate large differences in clinical practice, especially with regard to specificity.
Quené, H; Koster, M L
Previous experiments using a word-spotting task suggest that English listeners use metrically strong syllables to segment continuous speech into discrete words (Cutler & Norris, 1988). The present study is concerned with this metrical segmentation strategy in Dutch. Although Dutch and English share general metrical properties, they differ in ways that may affect segmentation. First, the acoustic cues for metrically strong syllables are less salient in Dutch than in English; hence a metrical segmentation strategy is less likely to be applied by Dutch listeners. Second, vowel quality depends less on metrical structure in Dutch than in English; hence segmentation in Dutch is presumably triggered by other acoustic cues, namely, those related to stress. Experiment 1 shows that stress strongly affects Dutch listeners' ability and speed in spotting Dutch monosyllabic words in disyllabic nonwords. Experiment 2, however, finds the same stress effect when only the target words are presented, without a subsequent syllable triggering segmentation. A third experiment shows a small effect of vowel quality on error scores, but not on latencies. These results suggest that Dutch listeners do not apply a metrical segmentation strategy. The discrepancy between the two languages suggests that segmentation strategies may depend on language-specific regularities in the phonology and in the lexicon.
Because of the lack of experience with permits in the Netherlands, and in view of the similarities between various other tradeable permit systems, the functioning of Dutch systems of tradeable fish, milk and manure quotas is discussed. Evaluation of these systems is based on criteria of effectiveness, target-group efficiency and government efficiency. These systems of tradeable permits appear to constitute a successful addition to the Dutch policy of direct regulation. Considering this, and the favorable American experience with the Emissions Trading Program, tradeable emission permits deserve a chance to be implemented in Dutch environmental policy. The question remains, however, whether the Dutch government is ready for such a step. 28 refs
Patel, Vaishali; McNamara, Lauren; Dullabh, Prashila; Sawchuk, Megan E; Swain, Matthew
To characterize nationwide variation and factors associated with clinical laboratories': (1) capabilities to send structured test results electronically to ordering practitioners' EHR systems; and (2) their levels of exchange activity, as measured by whether they sent more than three-quarters of their test results as structured data to ordering practitioners' EHR systems. A national survey of all independent and hospital laboratories was conducted in 2013. Using an analytic weighted sample of 9382 clinical laboratories, a series of logistic regression analyses were conducted to identify organizational and area characteristics associated with clinical laboratories' exchange capability and activity. Hospital-based clinical laboratories (71%) and larger clinical laboratories (80%) had significantly higher levels of capability compared to independent (58%) and smaller laboratories (48%), respectively; though all had similar levels of exchange activity, with 30% of clinical laboratories sending 75% or more of their test results electronically. In multivariate analyses, hospital and the largest laboratories had 1.87 and 4.40 higher odds, respectively, of possessing the capability to send results electronically compared to independent laboratories (pLaboratories located in areas with a higher share of potential exchange partners had a small but significantly greater capability to send results electronically and higher levels of exchange activity(pClinical laboratories' capability to exchange varied by size and type; however, all clinical laboratories had relatively low levels of exchange activity. The role of exchange partners potentially played a small but significant role in driving exchange capability and activity. Published by Elsevier B.V.
textabstractThe Dutch ‘Female Board Index 2008’ provides for the second year an overview of female representation on the Board of Directors and Supervisory Boards of 113 Dutch NV companies1 listed on Euronext Amsterdam. The companies were classified according to the percentage of women present on their combined Board of Directors and Supervisory Boards. The Dutch ‘Female Board Index’ also analyses the differences between male and female executive directors and supervisors ('non-executive dire...
van Steenbergen, Liza N; Spooren, Anneke; van Rooden, Stephanie M; van Oosterhout, Frank J; Morrenhof, Jan W; Nelissen, Rob G H H
Background and purpose A complete and correct national arthroplasty register is indispensable for the quality of arthroplasty outcome studies. We evaluated the coverage, completeness, and validity of the Dutch Arthroplasty Register (LROI) for hip and knee arthroplasty. Patients and methods The LROI is a nationwide population-based registry with information on joint arthroplasties in the Netherlands. Completeness of entered procedures was validated in 2 ways: (1) by comparison with the number of reimbursements for arthroplasty surgeries (Vektis database), and (2) by comparison with data from hospital information systems (HISs). The validity was examined by conducting checks on missing or incorrectly coded values in the LROI. Results The LROI contains over 300,000 hip and knee arthroplasties performed since 2007. Coverage of all Dutch hospitals (n = 100) was reached in 2012. Completeness of registered procedures was 98% for hip arthroplasty and 96% for knee arthroplasty in 2012, based on Vektis data. Based on comparison with data from the HIS, completeness of registered procedures was 97% for primary total hip arthroplasty and 96% for primary knee arthroplasty in 2013. Completeness of revision arthroplasty was 88% for hips and 90% for knees in 2013. The proportion of missing or incorrectly coded values of variables was generally less than 0.5%, except for encrypted personal identity numbers (17% of which were missing) and ASA scores (10% of which were missing). Interpretation The LROI now contains over 300,000 hip and knee arthroplasty procedures, with coverage of all hospitals. It has a good level of completeness (i.e. more than 95% for primary hip and knee arthroplasty procedures in 2012 and 2013) and the database has high validity. PMID:25758646
Full Text Available The caesarean delivery (CD rate has risen in most countries over the last decades, but it remains relatively low in the Netherlands. Our objective was to analyse the trends of CD rates in various subgroups of women between 2000 and 2010, and identify the practice pattern that is attributable to the relative stability of the Dutch CD rate.A total of 1,935,959 women from the nationwide Perinatal Registry of the Netherlands were included. Women were categorized into ten groups based on the modified CD classification scheme. Trends of CD rates in each group were described.The overall CD rate increased slightly from 14.0% in 2000-2001 to 16.7% in 2010. Fetal, early and late neonatal mortality rates decreased by 40-50% from 0.53%, 0.21%, 0.04% in 2000-2001 to 0.29%, 0.12%, 0.02% in 2010, respectively. During this period, the prevalence of non-vertex presentation decreased from 6.7% to 5.3%, even though the CD rate in this group was high. The nulliparous women with spontaneous onset of labor at term and a singleton child in vertex presentation had a CD rate of 9.9%, and 64.7% of multiparous women with at least one previous uterine scar and a singleton child in vertex presentation had a trial of labor and the success rate of vaginal delivery was 45.9%.The Dutch experience indicates that external cephalic version for breech presentation, keeping the CD rate low in nulliparous women and encouraging a trial of labor in multiparous women with a previous scar, could help to keep the overall CD rate steady.
Joustra, Sjoerd D; van der Plas, Evelyn M; Goede, Joery; Oostdijk, Wilma; Delemarre-van de Waal, Henriette A; Hack, Wilfried W M; van Buuren, Stef; Wit, Jan M
Accurate calculations of testicular volume standard deviation (SD) scores are not currently available. We constructed LMS-smoothed age-reference charts for testicular volume in healthy boys. The LMS method was used to calculate reference data, based on testicular volumes from ultrasonography and Prader orchidometer of 769 healthy Dutch boys aged 6 months to 19 years. We also explored the association between testicular growth and pubic hair development, and data were compared to orchidometric testicular volumes from the 1997 Dutch nationwide growth study. The LMS-smoothed reference charts showed that no revision of the definition of normal onset of male puberty - from nine to 14 years of age - was warranted. In healthy boys, the pubic hair stage SD scores corresponded with testicular volume SD scores (r = 0.394). However, testes were relatively small for pubic hair stage in Klinefelter's syndrome and relatively large in immunoglobulin superfamily member 1 deficiency syndrome. The age-corrected SD scores for testicular volume will aid in the diagnosis and follow-up of abnormalities in the timing and progression of male puberty and in research evaluations. The SD scores can be compared with pubic hair SD scores to identify discrepancies between cell functions that result in relative microorchidism or macroorchidism. ©2015 Foundation Acta Paediatrica. Published by John Wiley & Sons Ltd.
Full Text Available The Dutch ‘ZSM’ project was launched in March 2011 and implemented nationwide in 2013. Its (official aim is to (conclusively deal with frequently occurring crime (cases in a rapid, astute, selective, simple and society-oriented way, paying due attention to the interests of defendants, victims and society alike. The underlying assumption of the ZSM – and its accompanying focus on the speedy (out-of-court resolution of criminal cases that do not (necessarily merit the attention of the courts – is that ‘speed’ is beneficial to all involved: to defendants, to victims, to the police (and the Prosecution Service and to society as such. The question that concerns the authors is whether that assumption is correct. Does a speedy (out-of-court resolution indeed do justice to all involved, and particularly defendants and (purported victims? In this contribution, the Dutch ZSM process and its focus on the speedy out-of-court resolution is analyzed from the perspective of both the requirements of Article 6 of the European Convention and the social-scientific notion of procedural justice.
In August 1914, the Dutch government called up its citizens to enlist voluntarily in the army. This call-up failed. In 1915, the government tried to enlarge the army significantly by law. This attempt succeeded partially. At the end of the war, under threat of a leftwing revolution, the Netherlands
Ettema, Harmen B.; Hoppener, Marnix R.; Henny, Christiaan P.; Büller, Harry R.; Verheyen, Cees C. P. M.
All 110 Dutch orthopedic departments were sent a survey on perioperative thromboprophylaxis protocols, and 79% responded. After hip and knee replacements, all used pharmacological thromboprophylaxis: a low-molecular weight heparin (LMWH) in 87% of departments, which was most often combined with
Full Text Available In soybean, genic male sterility can be utilized as a tool to develop hybrid seed. Several male-sterile, female-fertile mutants have been identified in soybean. The male-sterile, female-fertile ms5 mutant was selected after fast neutron irradiation. Male-sterility due to ms5 was associated with the “stay-green” cotyledon color mutation. The cotyledon color trait in soybean is controlled by two loci, D1 and D2. Association between cotyledon color and male-sterility can be instrumental in early phenotypic selection of sterility for hybrid seed production. The use of such selection methods saves time, money, and space, as fewer seeds need to be planted and screened for sterility. The objectives of this study were to compare anther development between male-fertile and male-sterile plants, to investigate the possible linkages among the Ms5, D1 and D2 loci, and to determine if any of the d1 or d2 mutations can be applied in hybrid seed production. The cytological analysis during anther development displayed optically clear, disintegrating microspores and enlarged, engorged pollen in the male-sterile, female-fertile ms5ms5 plants, a common characteristic of male-sterile mutants. The D1 locus was mapped to molecular linkage group (MLG D1a and was flanked by Satt408 and BARCSOYSSR_01_1622. The ms5 and D2 loci were mapped to MLG B1 with a genetic distance ~12.8 cM between them. These results suggest that use of the d2 mutant in the selection of male-sterile line may attenuate the cost hybrid seed production in soybean.
Liu, Danyang; Dijkstra, Durk; de Vries, Jan B.; Wikstrom, Hakan V.
Previously, we have demonstrated that enone prodrugs of dopaminergic catecholamines represent a new type of dopamine (DA) agonist. Trans-1-propyl-1,2, 3,4,4a,5,10,10a-octahydrobenzo[g]quinoline-6,7-diol (TL-334), the active form
Šťastný, František; Tejkalová, H.; Skuba, I.; Páleníček, T.; Pliss, L.; Mareš, Vladislav; Krištofíková, Z.; Kaiser, M.; Höschl, C.; Bubeníková, V.; Balcar, V. J.
Roč. 8, Suppl. 3 (2004), s. 32-41 ISSN 1211-7579 R&D Projects: GA MŠk LN00B122; GA MZd NF6031; GA MZd NF7626 Institutional research plan: CEZ:AV0Z5011922 Keywords : schizophrenia * glutamate * dopamine Subject RIV: CD - Macromolecular Chemistry
Rosalinde J.A. Klein Woolthuis
Full Text Available This article discusses the strategies that sustainable entrepreneurs use to interact with their environment in the Dutch construction industry. The Dutch construction industry is under great pressure to move towards sustainability, and entrepreneurs are believed to be able to play a large role in this transition by introducing new products and new business practices. But how can entrepreneurs prosper in an environment that is not geared up towards such a change? And which strategies do they use to bend conditions in their favor? In this article we make use of the Market and System Failure Framework to analyze the pressures that entrepreneurs are confronted with when introducing sustainable innovations. We recognize that these pressures can be seen as bottlenecks, but that market and system failures can also create entrepreneurial opportunities. We interviewed 16 entrepreneurs in the Dutch construction industry to determine the influences they experienced from their environment and the strategies they use to deal with these. We conclude that we can distinguish between system building and following entrepreneurs, where the former aims to build a new system to challenge the old one, whereas the latter rather makes use of existing structures to build a business. We find that both strategies can be successful and that overall, the entrepreneurs confirm the belief that sustainability on people, planet and transparency aspects, can contribute very well to the long term profitability of the businesses the entrepreneurs are running. These in-depth insights into the influences from the context on the one hand, and the entrepreneurs’ strategic reactions on the other hand, contribute to our understanding of the interactions between entrepreneurs and the system context. This can help us to more effectively stimulate and support innovating entrepreneurs to contribute to the transition towards sustainability.
van der Wulp, Nickie Y; Hoving, Ciska; de Vries, Hein
two studies aimed to explore the advice Dutch midwives give and the information Dutch pregnant women and partners of pregnant women receive about alcohol consumption in pregnancy. study 1 included individual semi-structured interviews with midwives. Study 2 involved focus groups and individual semi-structured interviews with pregnant women and partners. Interview content was based on the I-Change Model. study 1 was conducted nation-wide; Study 2 was conducted in the central and southern regions of the Netherlands. 10 midwives in Study 1; 25 pregnant women and nine partners in Study 2. study 1 showed that midwives intended to advise complete abstinence, although this advice was mostly given when women indicated to consume alcohol. Midwives reported to lack good screening skills and sufficient knowledge about the mechanisms and consequences of antenatal alcohol use and did not involve partners in their alcohol advice. In Study 2, the views of pregnant women and partners were congruent to the findings reported in Study 1. In addition, pregnant women and partners considered midwives as an important source of information on alcohol in pregnancy. Partners were interested in the subject, had a liberal view on antenatal alcohol use and felt ignored by midwives and websites. Pregnant women indicated to receive conflicting alcohol advice from their health professionals. midwives' alcohol advice requires improvement with regard to screening, knowledge about mechanisms and consequences of antenatal alcohol use and the involvement of the partners in alcohol advice during pregnancy. training should be given to Dutch midwives to increase their screening skills and their alcohol related knowledge to pregnant women. Research is needed to determine how the midwife's alcohol advice to the partner should be framed in order to optimise the partner's involvement concerning alcohol abstinence in pregnancy. More attention to the topic at a national level, for example via mass media
van Rosse, F.
This thesis shows the first results of Dutch studies on the relation between ethnicity and patient safety. We used mixed methods to identify patient safety outcomes and patient safety risks in a cohort study in 4 urban hospitals among 763 Dutch patients and 576 ethnic minority patients. In a record
Veelo, Denise P.; Schultz, Marcus J.; Phoa, Kai Y. N.; Dongelmans, Dave A.; Binnekade, Jan M.; Spronk, Peter E.
OBJECTIVE: To determine tracheostomy-management practices in Dutch intensive care units (ICUs) and post-ICU step-down facilities. METHODS: We surveyed the physician medical directors of all Dutch nonpediatric ICUs that have : 5 beds suitable for mechanical ventilation. The survey asked for
In 1900, the Dutch Ministry of War sent four military observers to South Africa, in an attempt to come to terms with the latest developments in the military field. Once in South Africa, the promising young Dutch officers selected for the mission remained focused strongly on decisive battles Jominian style, which they considered ...
Dutch mothers display diverse labour market behaviour, though typically they work part-time, making modest use of childcare. It is generally assumed that Dutch women are free to make their own choices regarding employment. This narrative of 'choice' finds fertile ground in an era of general
Belt, J.C.; Berkum, van S.; Roza, P.
Russia¿s economy is booming; that¿s no news. Certainly not for Dutch agribusiness, looking at the steady increase of Dutch exports and investments in Russia. Not only our bigger agro-industries are involved, also medium size companies have found their way to access a market of 143 million consumers.
Groenhuijsen, M.S.; van Laanen, F.; Groenhuijsen, M.S.; van Laanen, F.
The authors have regarded euthanasia in the broader framework of Dutch penal policies. They present euthanasia as a typical example of the pragmatic - rather than dogmatic - way the Dutch try to tackle difficult moral problems in connection with the criminal justice system. Definitions, statutory
Lückerath – Rovers, M.
The Dutch ‘Female Board Index 2008’ provides for the second year an overview of female representation on the Board of Directors and Supervisory Boards of 113 Dutch NV companies listed on Euronext Amsterdam. The companies are ranked according to the percentage of women present on their combined Board
Van der Veen, R.A.C.; De Vries, L.J.
The share of microgeneration (power generation at the level of households and small businesses) in the Dutch electricity system continues to grow. Over time, this development may pose a threat to the reliability and efficiency of the Dutch electricity balancing market. We investigated possible
Doree, Andries G.
Several investigations by parliament, cabinet, justice and antitrust authorities have shown a widespread use of cartels and structural bid rigging within the Dutch construction industry. The reputation of the Dutch construction industry has been dented with both the general public and clients. As a
Wolf, de P.; Brouwer, W.B.F.; Rutten, F.H.
In this paper, we describe the Dutch pharmaceutical market, which is heavily regulated by the government. Through the regulation of prices and promoting prudent use, the Dutch government tries to bring down the cost of pharmaceuticals, which increases every year at a higher rate than total health
With the exception of Simon Schama's monograph on Dutch Patriots and French 'Liberators', the Batavian Revolution (1795-1806) has usually been interpreted as French-inspired and thus as 'alien' to the Netherlands. The original Dutch revolutionary achievements are underestimated as are those in the
Vaandrager, L.; Koelen, M.; Dieleman, F.
It is quite uncommon in The Netherlands to publish in Dutch so most publications about salutogenesis are in English. However, we identified 19 publications written in Dutch. These are publications in the field of development psychology, workplace health, mental health, medicine, care for people with
Ordelman, Roeland J.F.; van Hessen, Adrianus J.; de Jong, Franciska M.G.; Matousek, Vaclav; Mautner, Pavel; Moucek, Roman; Tauser, Karel
In this paper, ongoing work on the development of the speech recognition modules of a multimedia retrieval environment for Dutch is described. The work on the generation of acoustic models and language models along with their current performance is presented. Some characteristics of the Dutch
Meurs, Frank van; Hendriks, B.C.; Planken, B.C.; Barasa, S.N.; Groot, E.B. de; Nederstigt, U.; Arnhem, M. van; Smakman, D.
Many Dutch university students are expected to read and write academic research papers in English. In this article, we discuss a number of areas of EFL academic writing that are relevant for first-year Dutch business communication students. These students need to become familiar with quantitative
Meulen, van der H.A.B.; Asseldonk, van M.A.P.M.
In this paper mainstream and alternative sources of finance in
Dutch agriculture is analysed. Dutch farmers make use of
different sources of finance whereby bank loans continue to
serve as the major source of debt financing. The average bank
loan was approximately 740,000 euro per
S.W.I. Reeder (Suzan); K.P. de Roos; R.J.M. Vogels (R. J M); H.A.M. Neumann (Martino)
textabstractAim: To get insight into the frequency of venous leg ulceration in the Dutch dermatologic practice, and into how this profession treats this disease. Design: Material and Methods: An e-survey was conducted. To all Dutch dermatologists and residents dermatology an email was sent with an
Kramer, Gerard F.H.; Tyszler, Marcelo; Veer, van 't Pieter; Blonk, Hans
Objective: To find diets optimised on nutrition and environmental impact close to the current Dutch diet and to identify the most effective and acceptable options for mitigating environmental impact. Design: Linear programming was used to optimise diets of Dutch men and women aged 9–69 years,
Stoelinga, Mariëlle Ida Antoinette; Timmer, Mark; Unknown, [Unknown
These are the postproceedings of 17th Dutch Testing Day, held on the 29th of November 2011 at the - recently completely renovated - campus of the University of Twente. These postproceedings cover a selection of the material presented during the Dutch Testing Day. The synergy between academic and
textabstractAlmost 42,000 establishments, over 310,000 employees and approximately 13 billion Euro annual turnover (including VAT). This, in a nutshell, captures the Dutch hospitality industry in 2005. The aim of this study is to examine the functioning of the labour market in the Dutch hospitality
Centered around five inquiries, this thesis uses several concepts to analyze Dutch horticulture and FloraHolland Aalsmeer: moral economy, commodity, world system, networks, horticulture, aesthetics, masculinity, cooperative, and the market. It explores how Dutch horticulture was and is embedded in
Hiemstra, Djoerd; van Leeuwen, D.A.; Theune, M.; Theune, Mariet; Nijholt, Antinus; Nijholt, A.; Hondorp, G.H.W.; Hondorp, H.
This paper describes the first large-scale evaluation of information retrieval systems using Dutch documents and queries. We describe in detail the characteristics of the Dutch test data, which is part of the official CLEF multilingual test corpus, and give an overview of the experimental results of
Marlen, van B.; Polet, H.; Quirijns, F.J.
Fisheries managers go to great lengths to reduce cod catches in the North Sea, aiming for recovery of the cod stock. The Dutch government asked IMARES to provide an overview of all measures that are in place in various countries around the North Sea for reducing cod catches. The Dutch fisheries
Proper, K.I.; Hildebrandt, V.H.
Objective.: This study describes the total physical activity and the contribution of work to total physical activity among Dutch workers. The study was conducted in the Netherlands in the years 2000-2002. Methods.: 2,417 respondents of a cross-sectional survey representing the Dutch adult working
Boschman, E.; op den Akker, Hendrikus J.A.; Nijholt, A.; Nijholt, Antinus; Pantic, Maja; Pantic, M.; Poel, M.; Poel, Mannes; Hondorp, G.H.W.
In this paper a Neural Network is designed for Part-of-Speech Tagging of Dutch text. Our approach uses the Corpus Gesproken Nederlands (CGN) consisting of almost 9 million transcribed words of spoken Dutch, divided into 15 different categories. The outcome of the design is a Neural Network with an
Hoeijmakers, M.; de Bree, E.; Keijzer, M.
The present study investigates English spelling performance of Dutch grammar school students to establish whether Dutch grammar school students are able to spell words differing in complexity, as well as whether they are sensitive to the information available in the spellings (phonological,
Braam, A.W.; Beekman, A.T.F.; Knipscheer, C.P.M.; Deeg, D.J.H.; van den Eeden, P.
This study describes the distribution of depressive symptoms in older Dutch citizens (N = 3,020) across religious denominations. Reformed Calvinists had the lowest depressive scores (CES-D); Protestants from liberal denominations the highest; Roman Catholics, Dutch Reformed, and nonchurch members
Lance, K.T.; Georgiadou, Y.; Bregt, A.K.
This paper focuses on a geoportal from a “what lies beneath” perspective. It analyses processes of budgeting, planning, monitoring, performance measurement, and reporting of the national initiative titled Digital Information of the Dutch Subsurface (known by its Dutch acronym, DINO). The study is
van Boxtel, C.; van Drie, J.
The number of Dutch studies on the learning and teaching of history has increased substantially in the last ten years. Enhancing historical reasoning is a key topic in Dutch research on history education. This paper discusses recent and current empirical studies in the Netherlands on methods to
Waals, F.W. van der; Mohrs, J.; Foets, M.
Objective: To analyse sex differences among recipients of benzodiazepines in Dutch general practice. Design-Study of consultations and associated interventions as recorded in the Dutch national survey of general practice. Setting: Practices of 45 general practitioners monitored during 1 April to 30
van Soest, D.P.; Gerking, S.D.; van Oort, F.G.
This paper extends the work of Glaeser et al.(1992) by looking at effects of agglomeration economies on employment growth in Dutch city-industries and in very small (postal) zip code-industries in the Dutch province of South-Holland. At both levels of geographic detail, findings are broadly
Jansma, J.E.; Veen, E.J.; Kop, van de P.J.; Eijk, van O.N.M.
Since 2010, the Dutch City Network on Urban Agriculture (Stedennetwerk in Dutch), has linked up civil servants of fourteen cities in order to see opportunities, share knowledge and solve issues on urban agriculture in their cities. Though it started as an internally focused network for civil
De Jong, A.; Wink, J.; Sabbapathy, R.
Dutch Space, the largest space company in the Netherlands and part of Airbus Defence and Space, appointed a new CEO last year. The Leonardo Times sat down with the CEO Arnaud de Jong for an interview. We discuss his career, developments in Dutch Space, his take on competition in the commercial space
Leuw, Ed.; Haen Marshall, I.
This book gives an account of the national Dutch drug control strategy. Many researches in this field are described. Most of the chapters touch, in one way or another, on one of three key questions: (1) how is Dutch drug policy different from that of other countries; (2) how is the increasing
Fisheries policy is most effective when supported by fishers and the general public. Dutch citizens' and fishers' support for a selection of policy alternatives to enhance the sustainability of the Dutch North Sea cutter fleet is estimated, and the same groups' support for policy alternatives is
Looman, Moniek; Feskens, Edith Jm; de Rijk, Mariëlle; Meijboom, Saskia; Biesbroek, Sander; Temme, Elisabeth Hm; de Vries, Jeanne; Geelen, Anouk
To update the Dutch Healthy Diet index, a measure of diet quality, to reflect adherence to the Dutch dietary guidelines 2015 and to evaluate against participants' characteristics and nutrient intakes with the score based on 24 h recall (24 hR) data and FFQ data.
Jongbloed, Benjamin W.A.; Kuipers, S.K.; Kuper, G.H.; Sterken, E.
This paper presents CESAM, a macroeconometric model of the Dutch economy based on annual data. CESAM can be characterized as a Keynesian expenditure model including a neoclassical production model and a post-Keynesian financial model. This characterization holds for most of the Dutch
This article argues that cultural values should be included in policy making for the Dutch countryside. Since the sixteenth century the Dutch landscape has been a valued subject for art painters. This inheritance offers our rural areas a unique cultural value. This article focuses on the region
Kleinen, J.; van der Zwan, B.; Moors, H.; van Zeeland, T.
Dutch-Vietnamese relations go back as far as the beginning of the seventeenth century. For a long time, relations between the Dutch lion and the Vietnamese dragon have been fragile and even violent. Although the relations were not continuously bad, they remained distant rather than warm. Today
Koppen, Marjo van
In Dutch dialects, verbs and complementizers can bear different morphological affixes depending on which nominal element they agree with in their local syntactic domain. For instance, in a dialect such as tegelen Dutch, the complementizer agrees with the first conjunct of a coordinated subject,
Fijn, R; de Jong-van den Berg, LTW; Brouwers, JRBJ
A survey regarding the management of rational pharmacotherapy was conducted among all Dutch general hospitals in 1998. The response was 99% (n = 120). The presence of a drugs and therapeutics committee and antibiotic policies in Dutch general hospitals appears independent of hospital
X.E. Kramer (Xandra)
textabstractThis article provides an overview of the most important developments in Dutch private international law during the period January 1998-August 2002. The stormy codification of Dutch pri-vate international law in separate acts during the 1990’s was in a slower pace continued in the year
Besseling, P.J.; Lebouille, R.A.J.
In the framework of the project 'Paying differently for mobility' an option that is considered is to switch the Dutch Tax on Motor cars and Vehicles (BPM) to a higher tariff for the future road pricing system. Due to some special characteristics of the BPM, this will be a highly complex financial operation. In this article, we explore three variants for their effect on the vehicle market and on the budget. We also explain the advantages and disadvantages for several groups of car owners. [nl
The Dutch energy distribution companies are again facing important adaptations to current market forces. The operational activities of the conventional energy distribution companies are split into monopoly tasks and commercial activities. By separation of functions and by further technological developments and market trends quite different types of companies will emerge, such as grid operators, energy-telecommunications-environment concerns and energy sellers. Some companies will focus on grid operation, while others will clearly opt for more commercial enterprising. Just like other private companies energy companies will develop new activities in other markets based on their own corporate strategies. Grid operation may then become only a mirror element or be abandoned altogether. 5 figs
van Ewijk, E.
This PhD dissertation focuses on mutual learning processes of governmental and non-governmental actors involved in Dutch-Moroccan and Dutch-Turkish municipal partnerships in the period 2007-2011. These partnerships aim at strengthening local governance in Morocco and Turkey as well as in the
Poppel, G.van.; Schneijder, P.; Löwik, M.R.H.; Schrijver, J.; Kok, F.J.
As part of the Dutch Nutrition Surveillance System, cardiovascular risk factors and food consumption (24 h recall) as well as haematological, Fe and vitamin status (A, B6, C) were assessed in 126 Dutch boys aged 10-11 years (response 71%). Body mass index (BMI) and the sum of four skinfolds were
Biemans, H.J.A.; Mil, van M.
This study investigated the extent to which the learning styles of Chinese students differ from those of Dutch students. The study was conducted within the context of Englishlanguage Bachelor of Science programmes thatWageningen University offers together with China Agricultural University to Dutch
M. Lückerath-Rovers (Mijntje)
textabstractThe Dutch ‘Female Board Index 2008’ provides for the second year an overview of female representation on the Board of Directors and Supervisory Boards of 113 Dutch NV companies1 listed on Euronext Amsterdam. The companies were classified according to the percentage of women present on
Tersmette, W; van Bodegom, D; van Heemst, D; Stott, D; Westendorp, R
The world population is ageing and healthcare services require trained staff who can address the needs of older patients. In this study we determined how current medical education prepares Dutch students of medicine in the field of Gerontology and Geriatrics (G&G). Using a checklist of the essentials of G&G, we assessed Dutch medical education on three levels. On the national level we analysed the latest National Blueprint for higher medical education (Raamplan artsopleiding 2009). On the faculty level we reviewed medical curricula on the basis of interviews with program directors and inspection of course materials. On the student level we assessed the topics addressed in the questions of the cross-institutional progress test (CIPT). The National Bluepr int contains few specific G&G objectives. Obligatory G&G courses in medical schools on average amount to 2.2% of the total curriculum measured as European Credit Transfer System units (ECTS). Only two out of eight medical schools have practical training during the Master phase in the form of a clerkship in G&G. In the CIPT, on average 1.5% of questions cover G&G. Geriatric education in the Netherlands does not seem to be in line with current demographic trends. The National Blueprint falls short of providing sufficiently detailed objectives for education on the care of older people. The geriatric content offered by medical schools is varied and incomplete, and students are only marginally tested on their knowledge of G&G in the CIPT.
Full Text Available This article examines the ways in which ideas of greatness, reason of state, and state formation were employed in the creation of the Dutch empire. It focuses, in particular, on the role of corporations, including the Vereenigde Oost-Indische Compagnie or Dutch East India Company, in providing a platform for the implementation of those ideas. It then shows how the state moved to appropriate the entire domain of political thought from such corporations in the eighteenth and nineteenth centuries, while noting the revival of their political role in the twentieth century. The paper then turns to the question of the impact of this history on the present and therefore to a consideration of the methodological issues involved in that question. Het Nederlandse 'empire' in de intellectuele geschiedenisDit artikel onderzoekt de manieren waarop ideeën over grootheid, raison d’État, en staatsvorming gebruikt werden in de vorming van een Nederlands ‘empire’. Het focust in het bijzonder op de rol van handelsondernemingen, inclusief de Vereenigde Oost-Indische Compagnie, in het bieden van een platform voor de implementatie van deze ideeën. Vervolgens laat het zien hoe de staat zich het politieke denken van dit soort ondernemingen toe-eigende in de achttiende en negentiende eeuw, terwijl de politieke rol van ondernemingen een revival kende in de twintigste eeuw. Tenslotte zal de vraag naar de invloed van deze geschiedenis op het heden, en de methodologische kwesties die daarmee gepaard gaan, aan bod komen.
Full Text Available In this paper we discuss recent developments in administrative court proceedings in the Netherlands, called the New Approach. Along with developments leading to the New Approach, it became clear that the insights from research on procedural justice deserve particular attention. The goals of the judge's actions in this respect are both that the proceedings are fair and just and that parties perceive the way they are being treated during proceedings as fair and just.Within the New Approach we discern five procedural justice elements: (1 respect, (2 voice and due consideration, (3 some influence on how proceedings will continue, (4 an explanation of how the proceedings will continue and (5 direct interpersonal contact.The introduction of the New Approach shows two important bottlenecks in Dutch administrative court proceedings, which are (i the possible or supposed collision between legally right outcomes and procedural justice and (ii the lack of uniformity and predictability.Although what we describe and discuss in this paper focuses on the Dutch situation, many of these considerations apply to administrative court proceedings in other countries. The themes and difficulties that face the administrative law judge seem to be common to many countries.
Lansaat, Liset; van der Noort, Vincent; Bernard, Simone E; Eerenstein, Simone E J; Plaat, Boudewijn E C; Langeveld, Ton A P M; Lacko, Martin; Hilgers, Frans J M; de Bree, Remco; Takes, Robert P; van den Brekel, Michiel W M
Incidences of pharyngocutaneous fistulization (PCF) after total laryngectomy (TL) reported in the literature vary widely, ranging from 2.6 to 65.5%. Comparison between different centers might identify risk factors, but also might enable improvements in quality of care. To enable this on a national level, an audit in the 8 principle Dutch Head and Neck Centers (DHNC) was initiated. A retrospective chart review of all 324 patients undergoing laryngectomy in a 2-year (2012 and 2013) period was performed. Overall PCF%, PCF% per center and factors predictive for PCF were identified. Furthermore, a prognostic model predicting the PCF% per center was developed. To provide additional data, a survey among the head and neck surgeons of the participating centers was carried out. Overall PCF% was 25.9. The multivariable prediction model revealed that previous treatment with (chemo)radiotherapy in combination with a long interval between primary treatment and TL, previous tracheotomy, near total pharyngectomy, neck dissection, and BMI factors established in the prediction model. However, these factors explain enough of the differences that, compensating for these factors, hospital is no longer independently predictive for PCF. This nationwide audit has provided valid comparative PCF data confirming the known risk factors from the literature which are important for counseling on PCF risks. Data show that variations in PCF% in the DHNCs (in part) are explainable by the variations in these predictive factors. Since elective neck dissection is a major risk factor for PCF, it only should be performed on well funded indication.
Groth, Kristian A; Krag, Kirstine Stochholm; Hove, Hanne
BACKGROUND: Marfan syndrome is associated with morbidity and mortality due to aortic dilatation and dissection. Preventive aortic root replacement has been the standard treatment in Marfan syndrome patients with aortic dilatation. In this study, we present aortic event data from a nationwide Marfan...... syndrome cohort. METHOD: The nationwide cohort of Danish Marfan syndrome patients was established from the Danish National Patient Registry and the Cause of Death Register, where we retrieved information about aortic surgery and dissections. We associated aortic events with age, sex, and Marfan syndrome...
Kessing, Lars Vedel; Vradi, Eleni; Andersen, Per Kragh
OBJECTIVES: The aim of the present study was to describe prescription patterns and changes in these patterns over the last decade for patients diagnosed with bipolar disorder in mental healthcare, using population-based and nationwide data, and to relate the findings to recommendations from...... international guidelines. METHODS: A population-based, nationwide study was carried out. It included register-based longitudinal data on all patients with a first-ever contact with mental healthcare with a diagnosis of mania/bipolar disorder from the entire Danish population, and all prescription data...
Andersen, Mikkel; Johnsen, Søren Paaske; Sørensen, Jan Nørtved
A criteria-based nationwide Emergency Medical Dispatch (EMD) system was recently implemented in Denmark. We described the system and studied its ability to triage patients according to the severity of their condition by analysing hospital admission and case-fatality risks.......A criteria-based nationwide Emergency Medical Dispatch (EMD) system was recently implemented in Denmark. We described the system and studied its ability to triage patients according to the severity of their condition by analysing hospital admission and case-fatality risks....
Rhythms and Rhymes of Life: Music and Identification Processes of Dutch-Moroccan Youth is a comprehensive anthropological study of the social significance of music among Dutch-Moroccan youth. In the Netherlands, a Dutch-Moroccan music scene has emerged, including events and websites. Dutch-Moroccan
Rhythms and Rhymes of Life: Music and Identification Processes of Dutch-Moroccan Youth is a comprehensive anthropological study of the social significance of music among Dutch-Moroccan youth. In the Netherlands, a Dutch-Moroccan music scene has emerged, including events and websites. Dutch-Moroccan
IJspeert, Joep E G; Madani, Ariana; Overbeek, Lucy I H; Dekker, Evelien; Nagtegaal, Iris D
Distinguishing premalignant sessile serrated lesions (SSLs) from hyperplastic polyps (HPs) is difficult for pathologists in daily practice. We aimed to evaluate nationwide variability within histopathology laboratories in the frequency of diagnosing an SSL as compared with an HP within the Dutch population-based screening programme for colorectal cancer and to assess the effect of an e-learning module on interlaboratory consistency. Data were retrieved from the Dutch Pathology Registry from the start of the nationwide population screening programme, January 2014, until December 2015. An obligatory e-learning module was implemented among pathologists in October 2014. The ratio between SSL and HP diagnosis was determined per laboratory. Odds ratios (ORs) for the diagnosis of an SSL per laboratory were compared with the laboratory with the median odds (median laboratory), before and after implementation of the e-learning module. In total, 14 997 individuals with 27 879 serrated polyps were included; 6665 (23.9%) were diagnosed as SSLs, and 21 214 as HPs (76.1%). The ratio of diagnosing an SSL ranged from 5% to 47% (median 23%) within 44 laboratories. Half of the laboratories showed a significantly different OR (range 3.47-0.16) for diagnosing an SSL than the median laboratory. Variability decreased after implementation of the e-learning module (P = 0.02). Of all pathology laboratories, 70% became more consistent with the median laboratory after e-learning implementation. We demonstrated substantial interlaboratory variability in the histopathological diagnosis of SSLs, which significantly decreased after implementation of a structured e-learning module. Widespread implementation of education might contribute to more homogeneous practice among pathologists. © 2016 John Wiley & Sons Ltd.
Full Text Available The aim of present study was to show the main production parameters of sows based on 4359 crossbred Dutch Large White and Dutch Landrace pigs. The data were collected from 2004 to 2010 from Hungarian nucleus farms to analyze the lifetime performance of removed sows. The paper has studied the frequency of different culling reasons, the average lifespan of removed sows and the number of piglets born alive according to the parity. The result showed that the most frequent reasons for sow removal were the different fertility problems (29.5% and productivity problems (26.8%. In additional, it was detectable that the 35% of culling occured after the first farrowing or before this and there were removed 95% of the examined sows after the 8th parity. The highest litter size was observed at the 6th parity when the mean of lifespan of sows was 1210 days.
Eindhoven, D C; van Staveren, L N; van Erkelens, J A; Ikkersheim, D E; Cannegieter, S C; Umans, V A W M; Mosterd, A; van Wijngaarden, J; Schalij, M J; Borleffs, C J W
Since health insurance is compulsory in the Netherlands, the centrally registered medical claims data might pose a unique opportunity to evaluate quality of (cardiac) care on a national level without additional collection of data. However, validation of these claims data has not yet been assessed. Retrospective cohort study. National claims data ('national registry') were compared with data collected by patient records reviews in four representative hospitals ('validation registry'). In both registries, we extracted the national diagnosis codes for ST-segment elevation myocardial infarction and non-ST-segment elevation myocardial infarction of 2012 and 2013. Additionally, data on medication use at one year after acute myocardial infarction (AMI) was extracted from the Dutch pharmacy information systems and also validated by local patient records reviews. The data were compared at three stages: 1) validation of diagnosis and treatment coding; 2) validation of the hospital where follow-up has taken place; 3) validation of follow-up medical treatment after 365 days. In total, 3,980 patients ('national registry') and 4,014 patients ('validation registry') were compared at baseline. After one-year follow-up, 2,776 and 2,701 patients, respectively, were evaluated. Baseline characteristics, diagnosis and individual medication were comparable between the two registries. Of all 52,672 AMI patients in the Netherlands in 2012 and 2013, 81% used aspirin, 76% used P2Y12 inhibitors, 85% used statins, 82% used beta-blockers and 74% angiotensin converting enzyme inhibitors/angiotensin II antagonists. Optimal medical treatment was achieved in 49% of the patients with AMI. Nationwide routinely collected claims data in patients with an acute myocardial infarction are highly accurate. This offers an opportunity for use in quality assessments of cardiac care.
Bosman, Anna M T; Janssen, Marije
In the Netherlands, Turkish-Dutch children constitute a substantial group of children who learn to speak Dutch at the age of four after they learned to speak Turkish. These children are generally academically less successful. Academic success appears to be affected by both language proficiency and working memory skill. The goal of this study was to investigate the relationship between language skills and working memory in Turkish-Dutch and native-Dutch children from low-income families. The findings revealed reduced Dutch language and Dutch working-memory skills for Turkish-Dutch children compared to native-Dutch children. Working memory in native-Dutch children was unrelated to their language skills, whereas in Turkish-Dutch children strong correlations were found both between Turkish language skills and Turkish working-memory performance and between Dutch language skills and Dutch working-memory performance. Reduced language proficiencies and reduced working-memory skills appear to manifest itself in strong relationships between working memory and language skills in Turkish-Dutch children. The findings seem to indicate that limited verbal working-memory and language deficiencies in bilingual children may have reciprocal effects that strongly warrants adequate language education.
Vollebregt, T.; Rusch, H.
Chapter 1 provides a background to the Dutch power market, covering generation, transmission, distribution, supply, and laws and regulations. Chapter 2 reviews the key market events during 2001 and early 2002, providing analysis and background on an important and tumultuous period in the Dutch market. Chapter 3 explains the structure and timing of the key market mechanisms (Amsterdam Power Exchange, interconnector capacity auctions, TenneT 15-minute balancing market). Chapter 4 briefly reviews fuel price developments and discusses their impact on the costs of generation. Chapter 5 contains a detailed review of the traded Dutch power markets (APX, OTC, interconnection), including the linkages between these markets and an analysis of arbitrage opportunities
Full Text Available Interest in self-esteem has been fuelled by the suggestion that level of self-esteem is associated with psychological well-being. In the present study, we translated the Rosenberg Self-Esteem Scale (RSES into the Dutch language and evaluated its psychometric properties in a sample of 442 adults. The results of both exploratory and confirmatory factor analyses confirmed that a single-factor solution provides the best fit. In addition, the Dutch RSES showed high internal consistency as well as high congruent validity. Overall, these findings support the usefulness of the Dutch RSES as a measure for global self-esteem.
This doctoral thesis is about young Asian Dutch, panethnic Asian identities and identifications, and Asian/Asian Dutch popular culture. It addresses several pressing questions, including: why do young Asian Dutch, who were born and/or raised in the Netherlands, identify as Asian and construct Asian identities? What is the content or meaning of these Asian identities and identifications young Asian Dutch imagine? And how do these relate to young Asian Dutch’ Dutch and homeland identities and i...
Full Text Available Following Den Besten’s (2009 desiderata for historical linguistics of Afrikaans, this article aims to contribute some modern evidence to the debate regarding the founding dialects of Afrikaans. From an applied perspective (i.e. human language technology, we aim to determine which West Germanic language(s and/or dialect(s would be best suited for the purposes of recycling speech resources for the benefit of developing speech technologies for Afrikaans. Being recognised as a West Germanic language, Afrikaans is first compared to Standard Dutch, Standard Frisian and Standard German. Pronunciation distances are measured by means of Levenshtein distances. Afrikaans is found to be closest to Standard Dutch. Secondly, Afrikaans is compared to 361 Dutch dialectal varieties in the Netherlands and North-Belgium, using material from the Reeks Nederlandse Dialectatlassen, a series of dialect atlases compiled by Blancquaert and Pée in the period 1925-1982 which cover the Dutch dialect area. Afrikaans is found to be closest to the South-Holland dialectal variety of Zoetermeer; this largely agrees with the findings of Kloeke (1950. No speech resources are available for Zoetermeer, but such resources are available for Standard Dutch. Although the dialect of Zoetermeer is significantly closer to Afrikaans than Standard Dutch is, Standard Dutch speech resources might be a good substitute.
Aldenkamp, F.; Biesiot, W.; Geerts, H.M.; Nienhuys, K.; Soppe, W.
A survey is presented of the discussion on location sites for nuclear power plants in the Netherlands and the USA. It consists of two parts (A and B). This part (B) goes farther into the American reports already introduced briefly in part A. They are the reports of the IDCOR (nuclear power industry), ANS (American Nuclear Society), APS (American Physical Society), NRC (Nuclear Regulatory Commission) and UCS (Union of Concerned Scientists). Of each report a summary in English and an extended summary in Dutch is presented. Parts of the text of chapter 3 of the report 'Reactor accidents: the source term discussion' of the Technical University Twente (BC8501, 1985) are presented. 65 refs.; 15 figs.; 32 tabs
Rezaei, Saeed; Khatib, Mohammad; Baleghizadeh, Sasan
The present study is a nationwide survey of language identity among English language learners in Iran. The participants who completed the survey in this research included 1851 English language learners from different parts of the country who belonged to different genders, age groups and English language proficiency levels. The main instrument was…
... all levels of government to complete a cyber network security assessment so that a full measure of... DEPARTMENT OF HOMELAND SECURITY [Docket No. DHS-2011-0012] Nationwide Cyber Security Review (NCSR... comments; New Information Collection Request. SUMMARY: The Department of Homeland Security (DHS), National...
... for all levels of government to complete a cyber network security assessment so that a full measure of... DEPARTMENT OF HOMELAND SECURITY [Docket No. DHS-2011-0012] Nationwide Cyber Security Review (NCSR... comments; New Information Collection Request: 1670-NEW. SUMMARY: The Department of Homeland Security (DHS...
This document presents the Dutch National Plan combat nuclear accidents (NPK). Ch. 2 discusses some important starting points which are determining for the framework and the performance of the NPK, in particular the accident typology which underlies the plan. Also the new accident-classification system for the Dutch nuclear power plants, the standardization for the measures to be taken and the staging around nuclear power plants are pursued. In ch. 3 the legal framework of the combat nuclear accidents is described. In particular the Nuclear-power law, the Accident law and the Municipality law are pursued. Also the role of province and municipality are described. Ch. 4 deals with the role of the owner/licensee of the object where the accident occurs, in the combat of accident. In ch. 5 the structure of the nuclear-accident combat at national level is outlined, subdivided in alarm phase, combat phase and the winding-up phase. In ch.'s 6-12 these phases are elaborated more in detail. In ch.'s 10-13 the measures to be taken in nuclear accidents, are described. These measures are distinguished with regard to: protection of the population and medical aspects, water economy, drinking-water supply, agriculture and food supply. Ch. 14 describes the responsibility of the burgomaster. Ch.'s 15 and 16 present an overview of the personnel, material, procedural and juridical modifications and supplements of existing structures which are necessary with regard to the new and modified parts of the structure. Ch. 17 indicates how by means of the appropriate education and exercise it can be achieved that all personnel, services and institutes concerned possess the knowledge and experience necessary for the activities from the NKP to be executed as has been described. Ch. 18 contains a survey of activities to be performed and a proposal how these can be realized. (H.W.). figs.; tabs
In the Netherlands we are working with municipalities on the subjects of RES and RUE for over 15 years now. Over the last 4 years we worked with 250 out of 430 municipalities on setting up and executing their local climate policies. For this there was a national climate covenant between the national government, the association of municipalities and the association of provinces. The municipalities and provinces were supported through a subsidy scheme and the help of SenterNovem. Products like the climate menu, the climate scan and an organisational assessment were developed to aid the municipalities in their process. Through involvement of different stake holders within the municipality or a region concerning the climate policy and the execution thereof, production of RES is stimulated and goals on energy saving are more likely to be reached. Through the involvement of stake holders and by making climate change an integral part of the municipal organisation an irreversible process is started. Thus economic competitiveness and innovations are stimulated. The municipality and the region will gain economic strength through this. Results in the Netherlands on a municipal level are inspiring. More and more municipalities are developing long-term strategies at the moment. Goals like energy neutrality, climate neutrality and CO 2 neutrality in a set year are usually the basis of these strategies. Through these strategies Dutch municipalities become increasingly less dependent on energy sources outside their boarders. On a European level the Dutch approach ties in with the Covenant of Mayors which is launched by the EU.(author)
Hoof, J.J. van; Lely, N. van der; Pereira, R.R.; Dalen, W.E. van
Objective This study was conducted to investigate the number and characteristics of adolescent alcohol intoxication cases in hospital Departments of Pediatrics. The study also analyzes drinking patterns and intoxication characteristics. Method: Data were collected using the Dutch Pediatric
Geels, L.M.; Vink, J.M.; Beijsterveldt, C.E.M. van; Bartels, M.; Boomsma, D.I.
Objective: Multiple factors predict early alcohol initiation in teenagers. Among these are genetic risk factors, childhood behavioral problems, life events, lifestyle, and family environment. We constructed a developmental prediction model for alcohol initiation below the Dutch legal drinking age
This study investigates the impact of economic and marketing variables ( quality, price, and distribution), emotions ( fear, empathy, and guilt), social norms, and environment-related variables ( environmental concern, green behaviour, and perceived consumer effectiveness) on Dutch consumers'
Moes, F.; Houwaart, E.; Delnoij, D.; Horstman, K.
This paper examines a remarkable lawsuit in health care rationing. The Patients Association for Interstitial Cystitis sued the Dutch National Health Care Institute for alleged misconduct against Interstitial Cystitis patients, as the Institute decided that bladder instillations with chondroitin
Assendelft, W. J.J.; Pfeifle, C. E.; Bouter, L. M.
Background: In the Netherlands, there is increasing public and political interest in chiropractic treatment. There is, however, very little descriptive information available in the Netherlands on the chiropractic profession. Therefore, a survey was conducted among all Dutch chiropractors. Methods: A
Abstract. Book Title: Qualitative-Quantitative Analyses of Dutch and Afrikaans Grammar and Lexicon. Book Author: Robert S. Kirsner. 2014. John Benjamins Publishing Company ISBN 9789027215772, price ZAR481.00. 239 pages ...
Erumban, Abdul Azeez
This paper estimates service lifetimes for capital assets in Dutch manufacturing industries, using information on asset retirement patterns. A Weibull distribution function is estimated using a nonlinear regression technique to derive service lifetimes for three selected asset types: transport
Full Text Available http://dx.doi.org/10.5007/2175-8026.2012n62p127 It was not until the twentieth century, and especially the 1980s, that Dutch Gothic fiction began to flourish. This article gives an overview of the history of the Gothic in Dutch literature, and discusses the explanations given for the absence of a Dutch Gothic tradition. It then examines six Gothic novels from the 1980s in more depth to determine what kind of “cultural work” the Gothic does in late-twentieth century Dutch novels. In those novels, the Gothic is a way of expressing the ambivalences accompanying new societal relations following the 1960s, when constructs of the self in terms of gender and sexuality were reformulated.
Drachsler, Hendrik; Stoyanov, Slavi; Specht, Marcus
Drachsler, H., Stoyanov, S. & Specht, M. (2014, March). The Impact of Learning Analytics on the Dutch Education System. Paper presented at The 4th International Conference on Learning Analytics and Knowledge, Indianapolis, Indiana, USA.
Liem, M.C.A.; Liem, A.L.; Dongen, van E.P.A.; Carels, I.C.; Egmond, van M.; Kerkhof, A.J.F.M.
Previous studies reveal an elevated suicide rate for anaesthesiologists. We sought to examine anaesthesiologist suicide mortality and its underlying explanatory factors. Two studies were conducted in order to establish the suicide mortality figures among Dutch anaesthesiologists and to investigate
van der Horst, Mariska; van der Lippe, Tanja; Kluwer, Esther
Purpose - To investigate how work and family aspirations relate to occupational achievements and gender differences herein. Design/methodology/approach - Using data from 2009 we examined the relationship between career and childrearing aspirations and occupational achievements of Dutch parents.
A brief overview is given of the opinions of several players in the market for natural gas on the new Dutch Natural Gas Law, which is drafted within the framework of the liberalization of the European market for natural gas
Bosman, Anna M. T.; Janssen, Marije
In the Netherlands, Turkish–Dutch children constitute a substantial group of children who learn to speak Dutch at the age of four after they learned to speak Turkish. These children are generally academically less successful. Academic success appears to be affected by both language proficiency and working memory skill. The goal of this study was to investigate the relationship between language skills and working memory in Turkish–Dutch and native-Dutch children from low-income families. The f...
Lester Paul Gibson; Arthur R. Hastings; Leon A. LeMadeliene
Dutch elm disease (DED) and elm phloem necrosis are the two most serious diseases of elm in the United States (Figs. 1 and 2). Most native species of elm are susceptible to both diseases. Dutch elm disease is caused by a fungus, Ceratocystis u1mi (Buisman) C. Moreau, and is transmitted by two species of elm bark beetles-the smaller European elm bark beetle, Scolytus...
Full Text Available Bringing History Home: Postcolonial Immigrants and the Dutch Cultural ArenaThree Dutch-language monographs published in 2008-2009 by Ulbe Bosma, Lizzy van Leeuwen and Gert Oostindie in the context of the interdisciplinary research programme Bringing History Home, present a history of identity politics in relation to ‘postcolonial immigrants’. This term refers to some 500,000 people who since 1945 arrived in the Netherlands from Indonesia and the former Dutch New Guinea, Suriname or the Antillean islands in the Caribbean. Bosma traces the development of postcolonial immigrant organizations. In interaction with government policies, these organizations moved from mere socioeconomic emancipation struggles to mere cultural identity politics. Van Leeuwen takes such cultural identity politics as the starting point for her analysis of Indo-Dutch and Dutch Indies cultural initiatives and the competing interests at stake in the Indies heritage discourse. Oostindie discusses these developments in terms of community development and change within Dutch society at large. He introduces the notion of a ‘postcolonial bonus’. In postcolonial Netherlands, this bonus was available to immigrants on the grounds of a shared colonial past. Today, this bonus is (almost spent. The review discusses the three monographs, as well as the coherence of Bringing History Home as a research programme. Legêne argues, that notwithstanding valuable research outcomes, the very category of postcolonial immigrants does not constitute a convincing category of analysis.
Lilie M. Roosman
Full Text Available This study focuses on the way in which the Dutch monophthongal vowels are pronounced by Indonesian students. To investigate whether Indonesian students realize the Dutch vowels correctly, especially when they are stressed, I analysed duration and quality of stressed and unstressed Dutch vowels. Measurements were done on the duration and the formant frequencies of the vowels spoken by Indonesian students and by native speakers of Dutch as well. Statistical analysis showed that in general the differences in duration between vowels spoken by the Indonesian students and by the native speakers were not significant. However, the effect of stress on the lengthening of the vowels was stronger for the Indonesian students than for the native speakers. In addition, statistical analysis of the formant frequencies confirmed that the non-native speakers realized the Dutch vowels slightly differently from the Dutch native speakers. The Indonesian students pronounced the stressed vowels more clearly than their unstressed counterparts; yet their vowel diagram is smaller than the vowel diagram of the native speakers.
The Netherlands are the first European gas producer and exporter. The author proposes an analysis of the gas policy of this country. He first recalls some elements of context: peculiarities of energy as a domain of public policy, and characteristics of the Dutch political system. He recalls the historical development of the Dutch gas industry from the 1960's: political economics of natural gas and of competing fuels, development of the Groningen site as the keystone of the Dutch gas policy, and regulation of the industrial sector. In the next part, the author comments the emergence of energy as a topic of public debate from 1995, and how the Dutch gas policy has been put into question again: actors and interaction dynamics, stakes, present policy and perspectives
van Houtum, L; Heijmans, M; Rijken, M; Groenewegen, P
Healthcare providers are increasingly expected to help chronically ill patients understand their own central role in managing their illness. The aim of this study was to determine whether experiencing high-quality chronic illness care and having a nurse involved in their care relate to chronically ill people's self-management. Survey data from 699 people diagnosed with chronic diseases who participated in a nationwide Dutch panel-study were analysed using linear regression analysis, to estimate the association between chronic illness care and various aspects of patients' self-management, while controlling for their socio-demographic and illness characteristics. Chronically ill patients reported that the care they received was of high quality to some extent. Patients who had contact with a practise nurse or specialised nurse perceived the quality of the care they received as better than patients who only had contact with a GP or medical specialist. Patients' perceptions of the quality of care were positively related to all aspects of their self-management, whereas contact with a practise nurse or specialised nurse in itself was not. Chronically ill patients who have the experience to receive high-quality chronic illness care that focusses on patient activation, decision support, goal setting, problem solving, and coordination of care are better self-managers. Having a nurse involved in their care seems to be positively valued by chronically ill patients, but does not automatically imply better self-management. Copyright © 2016. Published by Elsevier Ireland Ltd.
van Ewijk, E.
This PhD dissertation focuses on mutual learning processes of governmental and non-governmental actors involved in Dutch-Moroccan and Dutch-Turkish municipal partnerships in the period 2007-2011. These partnerships aim at strengthening local governance in Morocco and Turkey as well as in the Netherlands. The research focuses on five case studies and indicate the partnerships lead to important forms of learning at both sides, including strengthening service delivery and working in multi-actor ...
Ras, Marcel; Kruithof, Gijsbert
Over the past years, more and more collections belonging to archives, libraries, media, museums, and knowledge institutes are being digitised and made available online. These are exciting times for ALM institutions. They are realising that, in the information society, their collections are goldmines. Unfortunately most heritage institutions in the Netherlands do not yet meet the basic preconditions for long-term availability of their collections. The digital objects often have no long lasting fixed reference yet. URL's and web addresses change. Some digital objects that were referenced in Europeana and other portals can no longer be found. References in scientific articles have a very short life span, which is damaging for scholarly research. In 2015, the Dutch Digital Heritage Network (NDE) has started a two-year work program to co-ordinate existing initiatives in order to improve the (long-term) accessibility of the Dutch digital heritage for a wide range of users, anytime, anyplace. The Digital Heritage Network is a partnership established on the initiative of the Ministry of Education, Culture and Science. The members of the NDE are large, national institutions that strive to professionally preserve and manage digital data, e.g. the National Library, The Netherlands Institute for Sound and Vision, the Netherlands Cultural Heritage Agency, the Royal Netherlands Academy of Arts and Sciences, the National Archive of the Netherlands and the DEN Foundation, and a growing number of associations and individuals both within and outside the heritage sector. By means of three work programmes the goals of the Network should be accomplished and improve the visibility, the usability and the sustainability of digital heritage. Each programme contains of a set of projects. Within the sustainability program a project on creating a model for persistent identifiers is taking place. The main goals of the project are (1) raise awareness among cultural heritage institutions on the
The Nationwide Truck Activity and Commodity Survey (NTACS) provides detailed activity data for a sample of trucks covered in the 1987 Truck Inventory and Use Survey (TIUS) for days selected at random over a 12-month period ending in 1990. The NTACS was conducted by the US Bureau of the Census for the US Department of Transportation (DOT). A Public Use File for the NTACS was developed by Oak Ridge National Laboratory (ORNL) under a reimbursable agreement with the DOT. The content of the Public Use File and the detailed design of the NTACS are described in the ORNL Report [open quotes]Technical Documentation for the 1990 Nationwide Truck Activity and Commodity Survey Public Use File[close quotes]. (1992). ORNL Technical Report No. TM-12188, Oak Ridge National Laboratory, Oak Ridge, TN 37831. The main purpose of this summary report is to provide selected tables based on the public use file.
Helgstrand, Frederik; Rosenberg, Jacob; Kehlet, Henrik
BACKGROUND: Incisional hernia repair is a frequent surgical procedure, but perioperative risk factors and outcomes have not been prospectively assessed in large-scale studies. The aim of this nationwide study was to analyze surgical risk factors for early and late outcomes after incisional hernia...... repair. STUDY DESIGN: We conducted a prospective nationwide study on all elective incisional hernia repairs registered in the Danish Ventral Hernia Database between January 1, 2007 and December 31, 2010. Main outcomes measures were surgical risk factors for 30-day readmission, reoperation (excluding...... recurrence), and mortality after incisional hernia repair. Late outcomes included reoperation for recurrence during the follow-up period. Follow-up was obtained by merging the Danish Ventral Hernia Database with the Danish National Patient Register. Results were evaluated by multivariate analyses. RESULT...
Janssen, M.P.M.; De Vries, L.; Phaff, J.C.; Van der Graaf, E.R.; Blaauboer, R.O.; Stoop, P.; Lembrechts, J
Radon concentrations and external exposure by nuclides of the U-238 decay chain were quantified for a typical Dutch townhouse using a series of interconnected computer models. The effect is studied of changes in parameter values which have simulated changes in building practices over the past decades. Three groups of parameters were distinguished: (1) the air-tightness of the building shell and the distribution of leaks over outer walls and ground floor, (2) the radon-relevant characteristics of the building materials, and 3) those characterising 'habits of the occupant', such as changing mechanical ventilation rate and opening of air inlets or doors. The relative importance of increased air-tightness and of substitution of concrete by other building materials in new dwellings is illustrated. On average changes in building practices clearly enhanced the radon concentration in the living room without affecting external exposure. In new, airtight dwellings the relative effect of occupant behaviour is demonstrated as considerably larger than in old ones.
Gorter, R C; te Brake, J H M; Eijkman, M A J; Hoogstraten, Joh
To develop an instrument measuring job resources among dentists, and to assess the relative importance of these resources and relate them to job satisfaction. 848 Dutch general dental practitioners (GDPs) received a questionnaire to monitor work experiences, including the Dentists' Experienced Job Resources Scale (DEJRS, 46 items, score range: 1 (not satisfying) to 5 (very satisfying), and the Dentist Job Satisfaction Scale (DJSS, 5 items, Cronbach's alpha = 0.85). A total of 497 (58.6%) dentists responded. Factor analysis (PCA) on the DEJRS resulted in 8 factors (Cronbach's alpha: 0.75 > alpha Entrepreneurship (M = 3.55, sd = 0.9); Material Benefits (M = 3.05, sd = 0.7); and Professional Contacts (M = 3.03, sd = 0.7). MANOVA indicated gender differences on: (Long-term) Patient Results (F(1,548) = 10.428, p = .001), and Patient Care (F(1,548) = 11.036, p r < 0.88. All subscales show a positive correlation with the DJSS. The DEJRS is a valuable and psychometrically sound instrument to monitor job resources as experienced by GDPs. Dentists report immediate results and aesthetics, and long-term results of working with patients to be the most rewarding aspects. All job resources showed a positive correlation with job satisfaction. The discussion includes conjecture that stimulating a greater awareness of job resources serves a major role in burnout prevention.
This podcast is based on the January 2012 CDC Vital Signs report. One in six adults binge drinks about four times a month. It's a problem nationwide but community-based strategies, such as reducing access to alcohol and increasing the price, can prevent binge drinking. Created: 1/3/2012 by Centers for Disease Control and Prevention (CDC). Date Released: 1/3/2012.
The authors report on a survey of 150 randomly-selected LP-gas marketers nationwide. Replies were solicited from every major geographical region. The purpose of the survey was to obtain a comprehensive sampling of information on local price increases, shipping difficulties, relations with customers, and strategies for the future. This paper presents a profile that sums up the effects of the propane emergency on marketers and customers.
Perez, Eva; Frank, Philipp; Micallef, Gilbert
be supported. In most cases, these upgrades increase the energy consumption of the network even further. This paper presents a nation-wide case study, based on a commercial network of a leading European operator, intended to provide a clear understanding of how the energy consumption of mobile networks...... is expected to evolve from 2012 until 2020. The study also considers an efficient network capacity evolution path, including base station equipment improvement forecasts....
Oliveira,Lúcio Garcia de; Alberghini,Denis Guilherme; Santos,Bernardo dos; Andrade,Arthur Guerra de
Objective: To estimate the frequency of polydrug use (alcohol and illicit drugs) among college students and its associations with gender and age group. Methods: A nationwide sample of 12,544 college students was asked to complete a questionnaire on their use of drugs according to three time parameters (lifetime, past 12 months, and last 30 days). The co-use of drugs was investigated as concurrent polydrug use (CPU) and simultaneous polydrug use (SPU), a subcategory of CPU that involves the ...
van Gelder, Celia W G; Hooft, Rob W W; van Rijswijk, Merlijn N; van den Berg, Linda; Kok, Ruben G; Reinders, Marcel; Mons, Barend; Heringa, Jaap
This review provides a historical overview of the inception and development of bioinformatics research in the Netherlands. Rooted in theoretical biology by foundational figures such as Paulien Hogeweg (at Utrecht University since the 1970s), the developments leading to organizational structures supporting a relatively large Dutch bioinformatics community will be reviewed. We will show that the most valuable resource that we have built over these years is the close-knit national expert community that is well engaged in basic and translational life science research programmes. The Dutch bioinformatics community is accustomed to facing the ever-changing landscape of data challenges and working towards solutions together. In addition, this community is the stable factor on the road towards sustainability, especially in times where existing funding models are challenged and change rapidly. © The Author 2017. Published by Oxford University Press.
Jochems, Anouk; Schouwenburg, Maartje G; Leeneman, Brenda; Franken, Margreet G; van den Eertwegh, Alfons J M; Haanen, John B A G; Gelderblom, Hans; Uyl-de Groot, Carin A; Aarts, Maureen J B; van den Berkmortel, Franchette W P J; Blokx, Willeke A M; Cardous-Ubbink, Mathilde C; Groenewegen, Gerard; de Groot, Jan Willem B; Hospers, Geke A P; Kapiteijn, Ellen; Koornstra, Rutger H; Kruit, Wim H; Louwman, Marieke W; Piersma, Djura; van Rijn, Rozemarijn S; Ten Tije, Albert J; Vreugdenhil, Gerard; Wouters, Michel W J M; van der Hoeven, Jacobus J M
In recent years, the treatment of metastatic melanoma has changed dramatically due to the development of immune checkpoint and mitogen-activated protein (MAP) kinase inhibitors. A population-based registry, the Dutch Melanoma Treatment Registry (DMTR), was set up in July 2013 to assure the safety and quality of melanoma care in the Netherlands. This article describes the design and objectives of the DMTR and presents some results of the first 2 years of registration. The DMTR documents detailed information on all Dutch patients with unresectable stage IIIc or IV melanoma. This includes tumour and patient characteristics, treatment patterns, clinical outcomes, quality of life, healthcare utilisation, informal care and productivity losses. These data are used for clinical auditing, increasing the transparency of melanoma care, providing insights into real-world cost-effectiveness and creating a platform for research. Within 1 year, all melanoma centres were participating in the DMTR. The quality performance indicators demonstrated that the BRAF inhibitors and ipilimumab have been safely introduced in the Netherlands with toxicity rates that were consistent with the phase III trials conducted. The median overall survival of patients treated with systemic therapy was 10.1 months (95% confidence interval [CI] 9.1-11.1) in the first registration year and 12.7 months (95% CI 11.6-13.7) in the second year. The DMTR is the first comprehensive multipurpose nationwide registry and its collaboration with all stakeholders involved in melanoma care reflects an integrative view of cancer management. In future, the DMTR will provide insights into challenging questions regarding the definition of possible subsets of patients who benefit most from the new drugs. Copyright © 2016 Elsevier Ltd. All rights reserved.
Oepkes, Dick; Page‐Christiaens, G. C. (Lieve); Bax, Caroline J.; Bekker, Mireille N.; Bilardo, Catia M.; Boon, Elles M. J.; Schuring‐Blom, G. Heleen; Coumans, Audrey B. C.; Faas, Brigitte H.; Galjaard, Robert‐Jan H.; Go, Attie T.; Henneman, Lidewij; Macville, Merryn V. E.; Pajkrt, Eva; Suijkerbuijk, Ron F.; Huijsdens‐van Amsterdam, Karin; Van Opstal, Diane; Verweij, E. J. (Joanne); Weiss, Marjan M.
Abstract Objective To evaluate the clinical impact of nationwide implementation of genome‐wide non‐invasive prenatal testing (NIPT) in pregnancies at increased risk for fetal trisomies 21, 18 and 13 (TRIDENT study). Method Women with elevated risk based on first trimester combined testing (FCT ≥ 1:200) or medical history, not advanced maternal age alone, were offered NIPT as contingent screening test, performed by Dutch University Medical laboratories. We analyzed uptake, test performance, redraw/failure rate, turn‐around time and pregnancy outcome. Results Between 1 April and 1 September 2014, 1413/23 232 (6%) women received a high‐risk FCT result. Of these, 1211 (85.7%) chose NIPT. One hundred seventy‐nine women had NIPT based on medical history. In total, 1386/1390 (99.7%) women received a result, 6 (0.4%) after redraw. Mean turn‐around time was 14 days. Follow‐up was available in 1376 (99.0%) pregnancies. NIPT correctly predicted 37/38 (97.4%) trisomies 21, 18 or 13 (29/30, 4/4 and 4/4 respectively); 5/1376 (0.4%) cases proved to be false positives: trisomies 21 (n = 2), 18 (n = 1) and 13 (n = 2). Estimated reduction in invasive testing was 62%. Conclusion Introduction of NIPT in the Dutch National healthcare‐funded Prenatal Screening Program resulted in high uptake and a vast reduction of invasive testing. Our study supports offering NIPT to pregnant women at increased risk for fetal trisomy. © 2016 The Authors. Prenatal Diagnosis published by John Wiley & Sons, Ltd. © 2016 The Authors. Prenatal Diagnosis published by John Wiley & Sons, Ltd. PMID:27750376
Oepkes, Dick; Page-Christiaens, G C Lieve; Bax, Caroline J; Bekker, Mireille N; Bilardo, Catia M; Boon, Elles M J; Schuring-Blom, G Heleen; Coumans, Audrey B C; Faas, Brigitte H; Galjaard, Robert-Jan H; Go, Attie T; Henneman, Lidewij; Macville, Merryn V E; Pajkrt, Eva; Suijkerbuijk, Ron F; Huijsdens-van Amsterdam, Karin; Van Opstal, Diane; Verweij, E J Joanne; Weiss, Marjan M; Sistermans, Erik A
To evaluate the clinical impact of nationwide implementation of genome-wide non-invasive prenatal testing (NIPT) in pregnancies at increased risk for fetal trisomies 21, 18 and 13 (TRIDENT study). Women with elevated risk based on first trimester combined testing (FCT ≥ 1:200) or medical history, not advanced maternal age alone, were offered NIPT as contingent screening test, performed by Dutch University Medical laboratories. We analyzed uptake, test performance, redraw/failure rate, turn-around time and pregnancy outcome. Between 1 April and 1 September 2014, 1413/23 232 (6%) women received a high-risk FCT result. Of these, 1211 (85.7%) chose NIPT. One hundred seventy-nine women had NIPT based on medical history. In total, 1386/1390 (99.7%) women received a result, 6 (0.4%) after redraw. Mean turn-around time was 14 days. Follow-up was available in 1376 (99.0%) pregnancies. NIPT correctly predicted 37/38 (97.4%) trisomies 21, 18 or 13 (29/30, 4/4 and 4/4 respectively); 5/1376 (0.4%) cases proved to be false positives: trisomies 21 (n = 2), 18 (n = 1) and 13 (n = 2). Estimated reduction in invasive testing was 62%. Introduction of NIPT in the Dutch National healthcare-funded Prenatal Screening Program resulted in high uptake and a vast reduction of invasive testing. Our study supports offering NIPT to pregnant women at increased risk for fetal trisomy. © 2016 The Authors. Prenatal Diagnosis published by John Wiley & Sons, Ltd. © 2016 The Authors. Prenatal Diagnosis published by John Wiley & Sons, Ltd. © 2016 The Authors. Prenatal Diagnosis published by John Wiley & Sons, Ltd.
Smink, F R E; van Hoeken, D; Donker, G A; Susser, E S; Oldehinkel, A J; Hoek, H W
Whether the incidence of eating disorders in Western, industrialized countries has changed over time has been the subject of much debate. The purpose of this primary-care study was to examine changes in the incidence of eating disorders in The Netherlands during the 1980s, 1990s and 2000s. A nationwide network of general practitioners (GPs), serving a representative sample (~1%) of the total Dutch population, recorded newly diagnosed patients with anorexia nervosa (AN) and bulimia nervosa (BN) in their practice during 1985-1989, 1995-1999, and 2005-2009. GPs are key players in the Dutch healthcare system, as their written referral is mandatory in order to get access to specialized (mental) healthcare, covered by health insurance. Health insurance is virtually universal in The Netherlands (99% of the population). A substantial number of GPs participated in all three study periods, during which the same case identification criteria were used and the same psychiatrist was responsible for making the final diagnoses. Incidence rates were calculated and for comparison between periods, incidence rate ratios. The overall incidence rate of BN decreased significantly in the past three decades (from 8.6 per 100,000 person-years in 1985-1989 to 6.1 in 1995-1999, and 3.2 in 2005-2009). The overall incidence of AN remained fairly stable during three decades, i.e. 7.4 per 100,000 person-years in 1985-1989, 7.8 in 1995-1999, and 6.0 in 2005-2009. The incidence rate of BN decreased significantly over the past three decades, while the overall incidence rate of AN remained stable.
Schreurs, Claire J.; Van Hoof, Joris J.; van der Lely, Nico
Purpose: To investigate hypothermia and its potential association with core and outdoor temperatures in adolescents suffering from acute alcohol intoxication. Methods: Data were derived from the Dutch Pediatric Surveillance System, which monitors alcohol intoxication among all Dutch adolescents.
ten Cate, K.; van de Vathorst, S.
To assess Dutch pediatricians' views on neuromuscular blockers for dying neonates. Qualitative study involving in-depth interviews with 10 Dutch pediatricians working with severely ill neonates. Data were analyzed using appropriate qualitative research techniques. Participants explained their view
Case note to a report of of the Dutch Ombudsman concerning a complaint on the information disclosure by the Dutch Social and Economic Council concerning the advantages and disadvantages of windtubrines
Meppelink, C.S.; van Weert, J.C.M.; Brosius, A.; Smit, E.G.
Objective To evaluate whether Dutch online health information (OHI) generally reflects message elements that support information processing and understanding among people with low health literacy. Methods We content-analyzed one hundred Dutch webpages about Ebola, fibromyalgia, ALS, losing weight,
Hoof, J.J. van; Lely, N. van der; Bouthoorn, S.H.; Dalen, W.E. van; Pereira, R.R.
Purpose: To monitor the prevalence of, and the circumstances leading to, adolescent alcohol intoxication admissions in Dutch hospital departments of pediatrics. Methods: Data were collected in 2007 and 2008, using the Dutch Pediatric Surveillance System, in which pediatricians received
Wammes, Birgitte; Oenema, Anke; Brug, Johannes
The objective was to evaluate a 3-year nationwide mass media campaign aimed at preventing weight gain. The campaign was aimed primarily at raising awareness of the importance of weight-gain prevention and bringing these issues to the attention of the Dutch public. Eleven serial, independent, cross-sectional, population-based telephone surveys were used to assess campaign awareness and impact (N ranged between 483 and 493 for each of the 11 surveys). The surveys were conducted before and after six campaign waves. Multiple linear and logistic regression analyses were used to test for trends over time and for differences among the surveys for campaign awareness, message recall, perceived body weight status, overweight-related risk perceptions, attitudes, perceived social support, self-efficacy expectations, and motivations for preventing weight gain. Campaign awareness ranged from 61% after the 1st campaign wave to 88.4% after the final wave. The campaign's television broadcasting activities were an important source of campaign awareness, from both the campaign's television commercials and television-based free publicity. Message recall ranged from 41.9% to 68.1%. Small positive differences were found in attitudes, perceived social support, and intentions for preventing weight gain. Additionally, the results suggest mixed effects on self-efficacy expectations and a negative effect on risk perception. The campaign resulted in high campaign awareness, especially as a result of television commercials and free publicity on television. The results suggest that the campaign was able to create more positive attitudes and motivation but lower risk perceptions and efficacy for preventing weight gain.
Cace, J.; Zijlstra, G. J.
The process of liberalisation of the Dutch energy market started in 1998 and will be completed in 2004 by opening the energy market to households and small enterprises. The fundaments of the open market are determined by the Electricity Law from 1998 and the Gas Law from 2000. The green electricity market was opened in July 2001 as a part of the environment protection package. A number of additional legal regulations, codes, procedures and agreements were developed in order to guarantee equal opportunities for all participants, create the market transparency, guarantee the continuity of supply and protect the consumer. These documents were developed by the 'Platform Versnelling Energieliberalisering', PVE (Platform for the acceleration of the liberalisation process). All relevant players from the energy market, including the major consumers, are represented in this advisory body. In the new market situation, the grid operators carry the essential responsibilities within the energy supply system. They are providing the technical security, registering the energy exchange through their grid and are generating the billing and the balance control information for suppliers and transport system operators respectively. The suppliers are the primary contact for the consumers. The complexity of the energy market liberalisation is aggravated by the difference in fundamental choices for the electricity and gas market. Electricity market is based on regulated third party access (TPA) and gas market is based on negotiated TPA. A lack of awareness of the necessity of an adequate information system appeared to be the most the most significant hurdle in establishing the open energy market. (author)
Hoeven, Arno; Janssen, Susanne; Driessen, Simone
markdownabstractOn the basis of interviews with music audiences, heritage practitioners, and cultural industry workers, this article explores how language use in Dutch popular music relates to local and historically situated taste patterns and music practices. Most popular music in the Netherlands is sung in English, Dutch, or dialects of the Dutch language. We discuss how these languages are used in Dutch popular music as an expression of cultural taste, cultural identities, and local herita...
Hoerz, F.; Bunch, T. E.; Oberbeck, V. R.
Evidence of shock metamorphism in the Dutch Peak diamictite in the Sheeprock Mountains, Utah, is reported. The Dutch Peak diamictite is of Proterozoic age and is a minor part of the Dutch Peak formation. A shocked sample, specimen A250, was collected during a brief visit of the Harker Canyon area of the Sheeprock Mountains. This sample consists of equant, anhedral grains of quartz, K-feldspar, and plagioclase. The crystallographic orientation of 244 lamellae systems in 106 grains was measured. It is presently difficult to evaluate the significance of this single specimen. Without additional and substantial field work, and petrographic characterization of this formation, a number of scenarios for the presence of a shocked clast and the emplacement of the entire formation remain viable.
van der Werff, S.; Koopmans, C.; Boyer, C.
The Dutch museum pass gives unlimited access for a year to most major Dutch museums and around the half of all Dutch museums for a fixed fee. The fee revenues are distributed among participating museums in proportion to the amount of visits by pass holders and their ticket prices. In this paper, it
Näring, G.W.B.; Roelofs, K.; Hoogduin, C.A.L.
Norms for the Dutch language version of the Stanford Hypnotic Susceptibility Scale, Form C (SHSS:C; Weitzenhoffer & Hilgard, 1962) are presented. These norms are based upon a sample of 135 students at a Dutch university. Generally, the psychometric properties of the Dutch version of the SHSS:C are
Roos M.B. Nieweg; Dr. C.P. van der Schans; Dr Harriët Jager-Wittenaar; Joke J. van de Kruk
OBJECTIVES: To compare the dietary intakes of Dutch nutrition and dietetics students with the Dutch RDA and the Dutch National Food Consumption Survey (DNFCS), and to assess whether dietary intake changes during education. DESIGN: Cross-sectional and longitudinal research (2004-2010). SETTING:
van der Leij, A.; Bekebrede, J.; Kotterink, M.
To investigate the effect of concurrent instruction in Dutch and English on reading acquisition in both languages, 23 pupils were selected from a school with bilingual education, and 23 from a school with education in Dutch only. The pupils had a Dutch majority language background and were
Kessens, J.M.; Leeuwen, D.A. van
In this paper, we describe N-best 2008, the first Large Vocabulary Speech Recognition (LVCSR) benchmark evaluation held for the Dutch language. Both the accent as spoken in the Netherlands (Northern-Dutch) and in Belgium (Southern-Dutch or Flemish), will be evaluated. The evaluation tasks are
Amelink-Verburg, M. P.; Verloove-Vanhorick, S. P.; Hakkenberg, R. M. A.; Veldhuijzen, I. M. E.; Bennebroek Gravenhorst, J.; Buitendijk, S. E.
OBJECTIVE: To assess the nature and outcome of intrapartum referrals from primary to secondary care within the Dutch obstetric system. DESIGN: Descriptive study. SETTING: Dutch midwifery database (LVR1), covering 95% of all midwifery care and 80% of all Dutch pregnancies (2001-03). POPULATION:
This doctoral thesis is about young Asian Dutch, panethnic Asian identities and identifications, and Asian/Asian Dutch popular culture. It addresses several pressing questions, including: why do young Asian Dutch, who were born and/or raised in the Netherlands, identify as Asian and construct Asian
Hartog, J.; Winkelmann, R.
We analyse post-war Dutch migration to New Zealand. We document that history, reflect on analytical and econometric modelling and then combine a sample of Dutch migrants in New Zealand with a representative sample of Dutch in The Netherlands to estimate wage equations and the determinants of the
de Weerd, Leonie; Groenhof, Feikje; Kollen, Boudewijn J.; van der Meer, Klaas
Background: Earlier research showed that healthcare in stroke could be better organized, aiming for improved survival and less comorbidity. Therefore, in 2004 the Dutch College of General Practitioners (NHG) and the Dutch Association of Neurology (NVN) introduced the 'Dutch Transmural Protocol
Cok, Kathryn Meriel
The results presented in this dissertation demonstrate the generous contribution that the Dutch Republic has made to the genre of basso continuo, including a survey of twenty-six Dutch sources from the 17th and 18th centuries. Focus has been made on the written record of the practice in the Dutch
van der Leij, Aryan; Bekebrede, Judith; Kotterink, Mieke
To investigate the effect of concurrent instruction in Dutch and English on reading acquisition in both languages, 23 pupils were selected from a school with bilingual education, and 23 from a school with education in Dutch only. The pupils had a Dutch majority language background and were comparable with regard to social-economic status (SES).…
This article reassesses women’s acknowledgement in Dutch Calvinist mission history by looking at women’s imagined place in the Dutch Calvinist missionary community between 1900 and 1942. It does so by looking at women’s position in the NZG’s (Dutch Missionary Society) mission to East Java and the
The early modern Dutch welfare system has often been described as relatively generous and efficient. Not only foreigners visiting the Dutch Republic, but also present-day historians have asserted that the Dutch, together with their English neighbours, stood out in early modern Europe in terms of
Boon, P.E.; Voet, van der H.; Raaij, van M.T.M.; Klaveren, van J.D.
We report the acute cumulative exposure to organophosphorus insecticides (OPs) and carbamates in the Dutch population and young children (1-6 years) via the diet. Residue data were derived from Dutch monitoring programmes performed during 2003-2005, and food consumption levels from the Dutch
Hinskens, F.L.M.P.; van Meel, Linda; van Hout, Roeland
How do speakers of current Turkish and Moroccan ethnolects of Dutch deal with phonemes that do not exist in their heritage languages and that are at the same time subject to pronounced regional and social variation in the Dutch speech community at large, such as the Dutch diphthong /εi/? This
The two-year post-MSc technological design traineeships organized by the Dutch Universities of Technology, and leading to the Professional Doctorate in Engineering (PDEng) degree, are still going strong after 28 years of existence. In 1986 the Dutch government and the Dutch industry - both aiming to
Oomes, N.; Appelman, R.; Witteman, J.
We predict the impact of the EU-Ukraine DCFTA on the Dutch economy using an international trade model. We find that, in the long run, the DCFTA could nearly triple Dutch exports to Ukraine and nearly double Dutch imports from Ukraine. These effects are not yet clearly visible in recent trade
Boersema, Jacob R.; Schimmel, Noam
We analyse the way in which the Holocaust is taught in The Netherlands, with an emphasis on critically examining the content of secondary school textbooks used to teach Dutch students about the history of the Holocaust. We also interview Dutch educators, government officials and academics about the state of Dutch Holocaust education. Our findings…
Bettendorf, L.; Van der Geest, S.A.; Varkevisser, M.
This paper analyses retail price adjustments in the Dutch gasoline market. We estimate an asymmetric error correction model on weekly price changes for the years 1996 to 2001. We construct five datasets, one for each working day. The conclusions on asymmetric pricing are shown to differ over these datasets, suggesting that the choice of the day for which prices are observed matters more than commonly believed. In our view, the insufficient robustness of outcomes might explain the mixed conclusions found in the literature. Using two approaches, we also show that the effect of asymmetry on Dutch consumer costs is negligible
Franck, Erik; De Raedt, Rudi; Barbez, Catherine; Rosseel, Yves
Interest in self-esteem has been fuelled by the suggestion that level of self-esteem is associated with psychological well-being. In the present study, we translated the Rosenberg Self-Esteem Scale (RSES) into the Dutch language and evaluated its psychometric properties in a sample of 442 adults. The results of both exploratory and confirmatory factor analyses confirmed that a single-factor solution provides the best fit. In addition, the Dutch RSES showed high internal consistency as well as...
The National Governors' Association, in conjunction with the Department of Energy's National Low-Level Waste Management Program, invited various representatives of states, regions, and federal agencies to comment on their perceptions of what major features would constitute a nationwide low-level waste management system. Three meetings were conducted and this report summarizes results of those meetings. The Low-Level Radioactive Waste Policy Act of 1980 placed primary responsibility on the states for disposal of low-level waste. Although initial efforts of states have been directed toward establishing compacts, it is evident that a successful long term system requires significant cooperation and communication among states, regions, federal agencies, and Congress
Mendsaikhan, Naranpurev; Begzjav, Tsolmon; Lundeg, Ganbold; Brunauer, Andreas; D?nser, Martin W.
In Mongolia, a Central Asian lower-middle income country, intensive care medicine is an under-resourced and-developed medical specialty. The burden of critical illness and capacity of intensive care unit (ICU) services in the country is unknown. In this nationwide census, we collected data on adult and pediatric/neonatal ICU capacities and the number of ICU admissions in 2014. All hospitals registered to run an ICU service in Mongolia were surveyed. Data on the availability of an adult and/or...
Krarup, Peter-Martin; Jorgensen, L N; Andreasen, A H
Aim: Anastomotic leakage (AL) is a major challenge in colorectal cancer surgery due to increased morbidity and mortality. Possible risk factors should be investigated differentially, distinguishing between rectal and colonic surgery in large-scale studies to avoid selection bias and confounding....... Method: The incidence and risk factors associated with AL were analysed in an unselected nation-wide prospective cohort of patient subjected to curative colonic cancer surgery with primary anastomosis and entered into The Danish Colorectal Cancer Group database between May 2001 and December 2008. Results...
Bischoff, Joakim Mutahi; Linderoth, Gitte; Aasvang, Eske Kvanner
BACKGROUND: Dysejaculation and pain from the groin and genitals during sexual activity represent a clinically significant problem in up to 4% of younger males after open inguinal herniorrhaphy. The aim of this questionnaire study is to assess the prevalence of dysejaculation and pain during sexual...... activity after laparoscopic inguinal herniorrhaphy on a nationwide basis. METHODS: The study population comprised all men aged 18-50 years registered in the Danish Hernia Database (n = 1,671) who underwent primary laparoscopic herniorrhaphy between January 1, 1998 and November 30, 2009. Questionnaires...
Nielsen, Philip Rising; Kragstrup, Tue Wenzel; Deleuran, Bent Winding
Viruses, bacteria and other infectious pathogens are the major postulated environmental triggers of autoimmunity. In the present nation-wide study we describe the association between infections and 29 autoimmune diseases. We used the Danish Civil Registration System to identify 4.5 million persons...... to the etiology of autoimmune diseases together with genetic factors....... born between 1945 and 2000. Information on infections and autoimmune diseases was obtained from the Danish Hospital Register. The cohort was followed from 1977 to 2012. Incidence rate ratios for developing an autoimmune disease were estimated using poisson regression. We found an association between...
Neter, J E; Dijkstra, S C; Dekkers, A L M; Ocké, M C; Visser, M; Brouwer, I A
Food-assistance program users are a specific group of nutritional concern, as they are often food insufficient and have poorer diet quality compared to non-food-assistance program users. The aim of our study was to assess dietary intake of Dutch food bank recipients (n = 167) and to compare this with dietary intake of a representative sample of the general population (Dutch National Food Consumption Survey (DNFCS-all): n = 1933), including a low-socioeconomic status (SES) sample (DNFCS-low SE...
Full Text Available Theodore Rodenburgh was in an exceptional position to become a literary mediator of Spanish poetics. He introduced the comedia nueva in the Dutch Republic at the beginning of the seventeenth century. This article investigates specifically how Rodenburgh dealt with Lope de Vega’s poetics, transforming them to make them fit the Dutch literary tradition. Through translation, adaptation and acculturation, the Iberian comedias became Dutch tragicomedies, plays that would become most popular in the Dutch Republic. Rodenburgh’s endeavours mark the initial phase of the transfer of the comedia nueva to the Dutch Republic.
Rademakers, J.J.D.J.M.; Muijsenbergh, M.E.T.C. van den; Slappendel, G.; Lagro-Janssen, A.L.M.; Borleffs, J.C.C.
CONTEXT: Sexual harassment of medical students has been the focus of many international studies. Prevalence rates from 18% to over 60% have been reported. However, a Dutch study at Nijmegen Medical School found the prevalence rate to be lower (13.3% in the total group; 20% among female students
With 35% of the total housing stock in the Netherlands (Ministry of VROM, 2004), the social rented sector plays an important role in Dutch housing, and its management can be of great importance to the success or failure of sustainability programs. Although sustainable building has been high on the
Because of its potential as an aquaculture species it has been widely used in aquaculture ventures in South Africa, specifically a stock known as Dutch catfish, a domesticated strain developed in the Netherlands. Mitochondrial DNA markers indicate that this stock is genetically distinct from the natural populations of C.
Literary celebrity results from a clash between two discursive configurations: literary authorship and popular celebrity. In order to gain an understanding of the contradictions that lie at the heart of literary celebrity, the authorial subjectivity of two Dutch authors are analyzed: Menno ter Braak
Hans van Ewijk; Peter Hendriks; dr Lia van Doorn
Fulltext via link. This article describes the perspective of newly started female Turkish and Moroccan Dutch professionals in social work and explores how they connect to the social work profession. Social work in the Netherlands attracts many of these young ‘new’ professionals. These
teams from a Dutch hospital and local teams of an orthopaedic hospital in Effiduase-Koforidua, Ghana. ... quality of care through education, management advice, and performing surgical interventions together with Ghanaian physicians/ surgeons. St. Joseph's Hospital ..... is mainly due to financial constraints with the result of.
OTB Research institute has established a long-term research program to performance-based maintenance procurement in the technical management of housing stock. Stakeholders: housing associations, contractors and the Dutch Building Research Foundation are directly involved in this research program.
As in many other countries the Dutch sociology of education has blossomed into a fully-fledged specialised branch of sociology since the beginning of the 1970s. A tradition of policy-oriented research has also consolidated the position of the sociology of education at the universities. The strength
This contribution describes the regulation of end-of-life decisions in neonatology in the Netherlands. An account is given of the process of formulating rules, which includes a report by the Dutch Association for Paediatrics, two Court rulings, a report by a Consultation Group appointed by the
Wittink, H.; Takken, T.; Groot, J.F. de; Reneman, M.; Peters, R.; Vanhees, L.
Objectives: To cross-validate the existing peak rate of oxygen consumption (VO2peak) prediction equations in Dutch law enforcement officers and to determine whether these prediction equations can be used to predict VO2peak for groups and in a single individual. A further objective was to report
In the 1930s Dutch elm disease (DED) was accidentally introduced from Europe into the United States. It had a devastating impact on American elm (Ulmus americana) and its relatives in urban and riparian environments. In the United States, the three-part pathosystem for DED is unique in that the affected elm species are North American, the pathogen originated in Asia,...
Barelds, Dick P. H.; Dijkstra, Pieternel
The present study examined the structure of a Dutch adaptation of the 40-item Narcissistic Personality Inventory (Raskin & Terry, 1988) in a community sample (n = 460) and a student sample (n = 515). Altering the response format of the NPI to a Likert-scale had no apparent effect on the responses.
Bloemert, Jasmijn; Jansen, Ellen; van de Grift, Wim
There is an increasing awareness that the inclusion of literature in foreign language (FL) curricula can be beneficial to language learners. Especially, the move towards integrated language and literature curricula is gaining ground. In this study we investigated the way English as a foreign language (EFL) is approached in Dutch secondary…
Fokkema, M R; Brouwer, D A; Hasperhoven, M B; Hettema, Y; Bemelmans, W J; Muskiet, F A
We compared the polyunsaturated fatty acid (PUFA) status of Dutch vegans and omnivores to investigate whether disparities can be explained by different diets and long chain PUFA (LCP) synthesis rates. Dietary intakes and fatty acid compositions of erythrocytes (RBC), platelets (PLT), plasma
Evers, Arnoud T.; van der Heijden, Beatrice I. J. M.; Kreijns, Karel; Gerrichhauzen, John T. G.
Purpose: The purpose of this paper is to report on a study that investigates the relationship between organisational factors, Teachers' Professional Development (TPD) and occupational expertise. Design/methodology/approach: A survey was administered among 152 Dutch teachers in secondary education. Findings: Analysis of the data revealed that of…
Bartelds, A.I.M.; Fracheboud, J.; Zee, J. van der
The Dutch sentinal practice network: relevance for public health policy, considers the now 20-year history of the Continuous Morbidity Registration Sentinel Stations the Netherlands. The book consists of two parts. In the first part general aspects are discussed: the origin of the project at the end
Ogurtsov, V.; Asseldonk, van M.A.P.M.; Huirne, R.B.M.
This article analyzed the impact of risk perception, risk attitude, and other farmer personal and farm characteristics on the actual purchase of catastrophe insurance by Dutch dairy and arable farmers. The specific catastrophe insurance types considered were hail–fire–storm insurance for buildings,
de Jong, A.
This Ph.D. thesis investigates capital structure decisions in Dutch firms. Firms are faced with the choice from a variety of sources of financing for the funding of their activities. These choices determine the firms' capital structures. Building on the well known theorems of Modigliani and Miller,
This article is about the pharma patent litigation sparked by Lundbeck's blockbuster drug for escitalopram. The article focuses on the trials and tribulations before the Dutch Patent Court of Appeal and the Supreme Court, while also briefly contrasting and comparing this with the decisions in
Mulder, Machiel; Zomer, Sigourney
This article analyzes Dutch consumers’ willingness to pay (WTP) for the welfare of broiler chickens and the consequences for nonhuman animal welfare policies. Using data from a discrete-choice experiment and a random parameter logit model, this study showed that consumers particularly value
Sweere, Y.; Kerkhof, G.A.; de Weerd, A.W.; Kamphuisen, H.A.C.; Kemp, B.; Schimsheimer, R.J.
The Sleep Disorders Questionnaire (SDQ) is a 176-item questionnaire designed to diagnose the presence of common sleep disorders. This study set out to assess the validity of a Dutch translation of the SDQ. 125 physician-referred patients (aged 16-82 yrs) with several sleep complaints and 20 controls
Buijs, Paul; Lopez Alvarez, Jose Alejandro; Veenstra, Marjolein; Roodbergen, Kees Jan
We study the collaborative transport planning for two autonomous business units of Fritom, a Dutch logistics service provider. This difficult planning problem does not fit any existing type of vehicle routing problem proposed in the academic literature; therefore, we define a new problem class, the
Mauser-Bunschoten, E. P.; Bresters, D.; van Drimmelen, A. A.; Roosendaal, G.; Cuypers, H. T.; Reesink, H. W.; van der Poel, C. L.; van den Berg, H. M.; Lelie, P. N.
Serum samples from 316 patients visiting the Dutch National Hemophilia Center were collected from 1979 to 1993 and stored at -30 degrees C. Patients were placed into three different groups: 1) patients ever treated with large pool non-hepatitis C virus (HCV)-safe concentrate (n = 179); 2) patients
Schols, J.M.G.A.; Crebolder, H.F.J.M.; Weel, C. van
Dutch nursing home care today includes a broad range of institutional and outreaching care functions. Medical care is an essential part of this care. Nursing home medicine in The Netherlands has developed as an officially acknowledged medical specialty. This is unique because The Netherlands is the
M. Kleppe (Martijn)
textabstractThis article demonstrates a media scientific approach by studying the use of photographs in Dutch History textbooks for High School pupils in the period 1970 – 2000. The quantity of photos has been determined as well as the types of pictures and its use as educational tool. Results show
Jerkovic, K.; van Offenbeek, M.A.; Slot, D.E.; van der Schans, C.P.
Objective: This study’s purpose was to compare the scope of practice of Dutch dental hygienists educated through a two- or three-year curriculum (‘old curriculum dental hygienists’ [OCDHs]) with that of hygienists educated through a new extended four-year curriculum leading to a bachelor’s degree
Jerkovic, K.; van Offenbeek, M. A. G.; Slot, D. E.; van der Schans, C. P.
Objective: This study's purpose was to compare the scope of practice of Dutch dental hygienists educated through a two- or three-year curriculum ('old curriculum dental hygienists' [OCDHs]) with that of hygienists educated through a new extended four-year curriculum leading to a bachelor's degree
For various reasons, Dutch waste policy has been dramatically changed in the last decade. Prevention of soil and groundwater pollution and a reduced occupation of the scarce space were important reasons for this change. An important effect of this policy is a reduction of the amount of organic
Terwel, K.C.; Waarts, P; E Rademaeker, de
The last 10 years the Dutch Building Industry was shocked by several major accidents. In 2001 the steel structure of a theatre in Hoorn collapsed during erection. No one was hurt, because it collapsed during the night. In 2002 part of the parking deck of a hotel collapsed just some time after a
van Klaveren, M.; Tijdens, K.
The story of the metal and electrical engineering collective agreement The current collective labour agreement covering the Dutch metal and electrical engineering industry dates as of 1985, when the earlier agreement was divided in an agreement for firms with 31 or more employees (the ‘large metal
van Heeswijck, Arthur
The legal protection of entrepreneurs in public procurement procedures has been a point of concern to the European Union legislator, leading to the adoption of well-known the Remedies Directives. This article examines the conformity of the Dutch system of judicial protection in the procurement field
Bakker, Winny; Van Oudenhoven, Jan Pieter; Van Der Zee, Karen I.
The present study examines the relationship of adult attachment styles with personality and psychological and sociocultural adjustment. A sample of 847 first-generation Dutch emigrants filled out measures for attachment styles, the Big Five, and indicators of psychological and sociocultural
Geelhoed, S.C.V.; Lagerveld, S.; Verdaat, J.P.; Scheidat, M.
In July 2014 aerial surveys to estimate the abundance of Harbour porpoises Phocoena phocoena on the Dutch Continental Shelf were conducted. In total, 229 sightings of 273 individual Harbour Porpoises were collected. Porpoise densities varied between 0.37-3.08 animals/km² in the (four) different
Geelhoed, S.C.V.; Scheidat, M.; Bemmelen, van R.S.A.
In March/April 2013 aerial surveys to estimate the abundance of Harbour porpoises Phocoena phocoena on the Dutch Continental Shelf were conducted. These surveys were conducted along predetermined track lines using distance sampling methods in four areas: A “Dogger Bank”, B “Offshore”, C “Frisian
An overview is given of the environmental quality in the Dutch province Noord-Holland in the year 2002. Special attention is paid to safety, energy, agriculture and the airport Schiphol. The report is available in electronic form in parts, discussing Social developments, the quality of Air, Soil, and Water, Public Health, Nature, Safety, Energy, Agriculture, and Schiphol (airport) [nl
Wittink, Harriet; Takken, Tim; de Groot, Janke; Reneman, Michiel; Peters, Roelof; Vanhees, Luc
Objectives: To cross-validate the existing peak rate of oxygen consumption (VO2peak) prediction equations in Dutch law enforcement officers and to determine whether these prediction equations can be used to predict VO2peak for groups and in a single individual. A further objective was to report
Collier, K.L.; Horn, S.S.; Bos, H.M.W.; Sandfort, T.G.M.
Attitudes toward lesbians and gays vary across national populations, and previous research has found relatively more accepting attitudes in the Netherlands as compared to the United States. In this study, we compared beliefs about and attitudes toward lesbians and gays in samples of Dutch and
Hattum, J.W.P.; Rupp, L.M.; Van den Doel, R.; Rupp, L.M.
This chapter investigates the lack of concrete targets for English pronunciation in Dutch secondary education and the concurrent lack of English pronunciation lessons. The chapter aims to answer two questions. Firstly, is mispronunciation really something of no concern? And secondly, how can the
van der Veen, M.
Explaining e-business adoptionThis dissertation deals with the explanation of e-business adoption in Dutch small and medium sized enterprises. The adoption of e-business plays an important part in making existing business more efficient and effective. Moreover, it is a tool for business development
Waijers, Patricia M C M; Ocké, Marga C; Rossum, Caroline T M van; Peeters, Petra H M; Bamia, Christina; Chloptsios, Yiannis; Schouw, Yvonne T van der; Slimani, Nadia; Bueno-de-Mesquita, H Bas
BACKGROUND: The need to gain insight into prevailing eating patterns and their health effects is evident. OBJECTIVE: This study aimed to identify dietary patterns and their relation to total mortality in older Dutch women. DESIGN: A principal component analysis of 22 food groups was used to identify
Overzee, van H.M.J.; Helmond, van A.T.M.
This report contains the results of the discard sampling programme of the Dutch pelagic freezer trawler fleet in European waters in 2010. The pelagic freezer trawler fishery targets pelagic species, namely herring (Clupea harengus), blue whiting (Micromesistius poutassou), horse mackerel (Trachurus
Frenkel, J.; Houten, S. M.; Waterham, H. R.; Wanders, R. J.; Rijkers, G. T.; Kimpen, J. L.; Duran, R.; Poll-The, B. T.; Kuis, W.
Dutch type periodic fever (DPF) is an autosomal recessive hereditary fever syndrome. Cases have been reported worldwide, the majority from France and The Netherlands. From infancy the patients suffer fever attacks that recur every 2-8 weeks, often precipitated by immunizations, infections or
Wiersinga, R.C.; Elbersen, H.W.; Yilmaz, G.
To research possibilities for Dutch businesses to be involved in the Turkish biodiesel sector, a short literature study and unstructured interviews with sector stakeholders were performed. Turkey is interested to develop its biofuel sector particularly to improve its security of energy supply, more
Kromhout, D.; Spaaij, C.J.K.; Goede, de J.; Weggemans, R.M.; Brug, Johannes; Geleijnse, Johanna M.; Goudoever, van Johannes B.; Hoes, Arno W.; Hopman, Maria T.E.; Iestra, Jolein A.; Mensink, Ronald P.; Pijl, Hanno; Romijn, Johannes A.; Schols, Annemie M.W.J.; Seidell, Jaap C.; Veer, van 't Pieter; Visser, Marjolein; Zwietering, Marcel H.
The objective of this study was to derive food-based dietary guidelines for the Dutch population. The dietary guidelines are based on 29 systematic reviews of English language meta-analyses in PubMed summarizing randomized controlled trials and prospective cohort studies on nutrients, foods and
Kromhout, D; Spaaij, C J K; de Goede, J; Weggemans, R M; Iestra, JA; Hoes, Arno W.
The objective of this study was to derive food-based dietary guidelines for the Dutch population. The dietary guidelines are based on 29 systematic reviews of English language meta-analyses in PubMed summarizing randomized controlled trials and prospective cohort studies on nutrients, foods and food
Swartjes FA; van der Linden AMA; van den Berg R
A new Soil-Groundwater Module has been developed for incorporation in the Dutch Risk Assessment System for New Chemicals. In this module, the exposure of humans and the environment to xenobiotic substances due to sewage sludge application have been determined. Exposure criteria were: 1.
Kramer, KJ; Moll, HC; Nonhebel, S; Wilting, HC
The consumption of food products involves emissions of greenhouse gases. Emissions occur in the various stages of the life cycle of food products. In this paper we discuss the greenhouse gas emissions, CO2, CH4, and N2O, related to Dutch household food consumption. Combinations of greenhouse gas
Veul, Romy; van Charldorp, T.C.; Soudijn, Melvin
In this paper we analyze how Dutch Public Prosecution’s press releases about money laundering and underground banking are received by producers and consumers of online news reports. First we take a closer look at how journalists (re)framed six official press releases in 75 news reports. It turns out
Jansen Hendriks, Gerda
abstractThe article looks back at the films commissioned and produced by the Dutch governments about their colony in teh East-Indies between 1912 and 1962. The main focus is on the newsreels and documentaries about the colonial war between the Netherlands and Indonesia from 1945 to 1949. The
van Bergen, Diana; Bos, Henny M.W.; van Lisdonk, jantine; Keuzenkamp, S; Sandfort, T.G.M
We examined Netherlands Institute for Social Research data, collected between May and August 2009, on 274 Dutch lesbian, gay, and bisexual youths. The data showed that victimization at school was associated with suicidal ideation and actual suicide attempts. Homophobic rejection by parents was also
Postma, E.; Hooft, van W.F.; Wieren, van S.E.; Breukelen, van L.
In this study we investigated microsatellite variation in Dutch roe deer (Capreolus capreolus) populations. We used 65 tissue samples from culled animals from three populations (Amsterdamse Waterleidingduinen, National Park Zuid-Kennemerland and Flevopolder). The first two are dune populations and
Developmental dyslexia is a neurobiological disorder, characterized by deficits in the auditory (phonological), visual, motor and linguistic domains. In the longitudinal Dutch Dyslexia Programme (DDP; (van der Leij et al., 2013; van der Leij & Maassen, 2013)) 180 children with a familial risk of
van Dellen, Teije; Klercq, Jumbo; Buiskool, Bert-Jan
Lifelong learning has never been an integral part of the Dutch educational culture. Nevertheless, nowadays yearly many adults (about 17.8% in 2015) are after either or not finishing initial education in some respect emergently participating in (continuing) second, third or more learning paths
General characteristics of bicycle and moped use, including safety aspects of cycling and moped riding, in the Netherlands, are presented. The Dutch governmental policy regarding safety of cyclists and moped riders is explained. The results of evaluations concerning the safety of cycle lanes and
Gameren-Oosterom, H.B.M.; Dommelen, P. van; Lanting, C.I.; Oudesluys-Murphy, A.M.; Buitendijk, S.; Buuren, S. van; Wouwe, J.P. van
Objective: The majority of children with Down syndrome (DS) have concomitant disorders, such as congenital heart defects (CHD), celiac disease, and hypothyroidism. We aim to establish growth patterns of height in Dutch children with DS, while taking into account the influence of the concomitant
Berg, Alan; Scheffel, Maren; Drachsler, Hendrik; Ternier, Stefaan; Specht, Marcus
We present the collected experiences since 2012 of the Dutch Special Interest Group (SIG) for Learning Analytics in the application of the xAPI standard and best practices around the application of xAPI in various contexts. We present three projects that apply xAPI in very different ways and publish a consistent set of xAPI recipes.
“Nutrition education in Dutch primary schools” School-based nutrition education programmes have increasingly been used to teach children about nutrition and to provide them with the skills to make healthy food choices. As these programmes differ in content and delivery,
In 1987 Chris Smeenk wrote in this journal about the libraries of the Dutch art historical institutes. In the 22 years that have since passed many changes have occurred, perhaps most notably the merging of the many autonomous institute libraries into larger ones. Has this led to a more professional
de Boer, Harry; Goedegebuure, Leo
As one of the first countries in Europe to do so, The Netherlands moved towards a new relationship between the state and the higher education institutions in the mid-1980s. Autonomy, quality and accountability were key considerations in this move. In 2006 the Dutch government proposed another radical innovation in its approach to higher education…
William N., Jr. Cannon; Jack H. Barger; David P. Worley
Recent research has shown that prompt removal of diseased elms reduces the incidence of Dutch elm disease more than sanitation practice that allows diseased elms to remain standing into the dormant season. The key to prompt removal is repeated surveys to detect diseased elms as early as possible. Intensive sanitation can save more elms and cost less than the more...
Delen, G.P.A.J.; Peters, R.J.; Verhoef, C.; van Vlijmen, B.
We present the findings from a Dutch field study of a representative sample of 30 outsourcing deals totalling to more than 100 million Euro, where both customers, corresponding IT-outsourcing providers and their intermediaries (if present) participated. Of the 30 deals, 18 were successful. As the
van Bergen, D.D.; Bos, H.M.W.; van Lisdonk, J.; Keuzenkamp, S.; Sandfort, T.G.M.
We examined Netherlands Institute for Social Research data, collected between May and August 2009, on 274 Dutch lesbian, gay, and bisexual youths. The data showed that victimization at school was associated with suicidal ideation and actual suicide attempts. Homophobic rejection by parents was also
Experience of collaboration between a Dutch surgical team in a Ghanaian Orthopaedic Teaching Hospital. ... medical teams from our hospital were deployed to St. Joseph's Hospital. These teams were completely self-supporting. They were encouraged to work together with the local-staff. Apart from clinical work, effort was
Haasnoot, Tim; Kraan, M.L.; Bush, S.R.
This paper focuses on the transition in the Dutch cutter fleet-targeting flatfish, from the conventional beam trawl to the pulse trawl fishing gear. In doing so,we explore the process of gear transition, presenting the challenges that fishers and policy-makers face.The pulse trawl technique
Oude Lansink, A.G.J.M.; Ondersteijn, C.J.M.
Profitability of Dutch greenhouse firms is largely dependent on energy costs, and policy makers focus on reducing the use of energy by these firms. This article uses Russell measures of TE to develop indicators of energy productivity growth. Results show that energy productivity grew by 2.8%
Rademakers, J.J.D.J.M.; Muijsenbergh, M.E.T.C. van den; Slappendel, G.; Lagro-Janssen, A.L.M.; Borleffs, J.C.C.
Context Sexual harassment of medical students has been the focus of many international studies. Prevalence rates from 18% to over 60% have been reported. However, a Dutch study at Nijmegen Medical School found the prevalence rate to be lower (13.3% in the total group; 20% among female students
Emerging Memory is about cultural memory in the Netherlands of a military expedition in the Dutch East Indies in 1904, during which the colonial army made photographs of the massacred inhabitants of several villages on the island of Sumatra. Over the past century, as this study shows, these
Human thermal comfort in urban outdoor places was generally not an issue in Dutch urban design. This neglect shows problematic effects of discomfort, but also missed chances in urban life quality. The existing problems are alleviated due to the expected effects of climate change with even higher
Lippe, Tanja van der
Balancing work with family life has become one of the most important issues for families nowadays. In this article I study the varying degrees of success of governance structures in households and firms in dealing with competing time claims. Using Dutch data from firms, employees and their spouses
The discourse between the Dutch Reformed Church (DRC) and race is a difficult and ... An altered social distance scale is used to measure church acceptance. In the discourse on race, acceptance and unity in the DRC with regard to racial prejudice and .... of variable intensity – of a subject in regard to others perceived and.
Luiz Carlos Bresser-Pereira
Full Text Available The Dutch disease is a major market failure originated in the existence of cheap and abundant natural or human resources that keep overvalued the currency of a country for an undetermined period of time, thus turning non profitable the production of tradable goods using technology in the state-of-the-art. It is an obstacle to growth on the demand side, because it limits investment opportunities. The severity of the Dutch disease varies according to the extent of the Ricardian rents involved, i.e., according to the difference between two exchange rate equilibriums: the ‘current’ or market rate and the ‘industrial’ rate - the one that make viable efficient tradable industries. Its main symptoms, besides overvalued currency, are low rates of growth of the manufacturing industry, artificially high real wages, and unemployment. Its neutralization requires managing the exchange rate. The principal instrument for that is a sales or export tax on the commodities that give origin to the Dutch disease. In order to neutralize it policymakers face major political obstacles since it involves taxing exports and reducing wages. Finally, this papers argues that there is an extended concept of Dutch disease: besides having its origin in natural resources, it may arise from cheap labor provided that the ‘wage spread’ in the developing country is considerably larger than in the developed one - a condition that is usually present.
de Waardt, J.H.M.
In the 1570s the structure of the Catholic Church had collapsed in the Dutch Republic, but soon after 1580 a process of reconstruction set in. At first exorcism and other types of faith healing were deployed by both secular and regular Catholic clergy. In time the secular clergy became less willing
Bakker, Winny; Van der Zee, K.I.; Van Oudenhoven, Jan Pieter
This experimental questionnaire study examined individual differences in affective and normative reactions to acculturation strategics. A sample of 265 Dutch emigrants with a dual cultural background read scenarios describing the experiences of an emigrant. Eight (4 × 2) different scenario versions
Bakker, Winny; Van der Zee, Karen; Van Oudenhoven, Jan Pieter
This experimental questionnaire study examined individual differences in affective and normative reactions to acculturation strategies. A sample of 265 Dutch emigrants with a dual cultural background read scenarios describing the experiences of an emigrant. Eight (4 x 2) different scenario versions
Diehl, Katharine S.
Some hitherto unreported and uncataloged publications which the Dutch East India Company printed in Ceylon during the eighteenth century were discovered through a search of the Ceylon National Archives, Wolvendaal Church Archives, and three libraries during the early months of 1971. (11 references) (Author/NH)
Redeker, Gisela; van der Vliet, Nynke; Gruber, Helmut; Redeker, Gisela
This study explores some of the factors that influence the probability that a coherence relation will be explicitly marked with a connective. In a corpus of 80 Dutch texts from expository and persuasive genres with annotations of the coherence structure (using Rhetorical Structure Theory, RST) and
Keij, B.M.|info:eu-repo/dai/nl/374786097; Kager, R.W.J.|info:eu-repo/dai/nl/072294124
In this chapter the early acquisition of word stress is discussed. This study is aimed at examining rhythmic preferences for either strong-weak or weak-strong stress patterns of Dutch-learning infants between 4 and 8 months of age. It is complementary to previous rhythmic preference studies
van der Vooren, A.; Alkemade, F.; Hekkert, M.P.
This paper explores how automotive firms positioned their portfolio since the introduction of energy labels for cars. Using data on product characteristics of automobiles offered on the Dutch market over the period 2001-2010, we analyse how car manufacturers' product portfolios have changed.
Dirkzwager, A.J.E.; Bramsen, I.; Adèr, H.J.; van der Ploeg, H.M.
This study examines secondary traumatization among 708 partners and 332 parents of Dutch peacekeepers (i.e., personnel who participated in military actions implemented by international organizations such as the United Nations). Partners or parents of peacekeepers with 4 levels of posttraumatic
Dirkzwager, A.J.E.; Bramsen, I.; Ader, H.; Ploeg, H.M. van der
This study examines secondary traumatization among 708 partners and 332 parents of Dutch peacekeepers (i.e., personnel who participated in military actions implemented by international organizations such as the United Nations). Partners or parents of peacekeepers with 4 levels of posttraumatic
Since 1957 the Film Museum in Amsterdam has been in possession of the Desmet Collection which contains the estate of the Dutch cinema owner and film distributor Jean Desmet (1875-1956). The collection comprises almost nine hundred European and American films in all genres, a collection of publicity
This paper estimates service lifetimes for capital assets in Dutch manufacturing industries, using information on asset retirement patterns. A Weibull distribution function is estimated using a non-linear regression technique to derive service lifetimes for three selected asset types: transport
The acquisition of finiteness is one of the most studied phenomena in both first and second language development. Within a functional framework, Dimroth et al. (2003) suggest that German and Dutch children follow a uniform acquisition path in the development of the target-like expression of
Huik, van M.M.; Bock, B.B.
Purpose ¿ The purpose of this paper is to provide insights into the rationale of Dutch pig farmers concerning animal welfare and animal-friendly production. It aims to show the interrelations between farmers' production logic, their ideas about good farming and animal welfare and the characteristics
An overview is given of the political and decision making process of the energy market liberalization in the Netherlands, based on interviews with and opinions of former ministers, representatives of the Dutch parliament, administrators, and other highplaced representatives of local governments, associations and energy companies [nl
Oud-de Glas, Maria; Peels, Fons
Reports on levels of foreign language education and foreign language competence among Dutch students, discussing the sharp decline in the teaching of French and German, a lack of foreign language training in technical education, where it is most needed, and the limitations of the data collected regarding foreign language attainment in the…
abstractThe adoption of computers in Dutch museums has been marked by the changing technology as much as by the interpretation of what the technology is meant to do. The Social Construction of Technology framework is used to review the adoption of a digital work method and to highlight the
H.W. Volberda (Henk); F.A.J. van den Bosch (Frans)
textabstractIn this essay, we challenge the present dominant emphasis in the Dutch Innovation Debate on the creation of technological innovations, the focus on a few core technologies, and the allocation of more financial resources. We argue that managerial capabilities and organizing principles for
Kuhn, P.; Kooreman, P.; Soetevent, A.R.; Kapteyn, A.
In the Dutch Post Code Lottery a postal code (19 households on average) is randomly selected weekly, and sizeable prizes (€12,500 per lottery ticket) are awarded to lottery participants living in that postal code. In addition to the monetary prizes, one of the winners wins a BMW. We analyze data on
Braam, A.W.; Beekman, A.T.F.; van Tilburg, T.G.; Deeg, D.J.H.; van Tilburg, W.
It has been suggested that religiosity helps prevent depression in older people. This study examines the association between religious involvement and depression in older Dutch citizens and focuses on models of the mechanism in which religious involvement has an impact on other factors related to
Kooij, R.E.; Jamakovic, A.; Kesteren, F. van; Koning, T.C.M. de; Theisler, I.B.; Veldhoven, P.
Although being very popular all around the globe, soccer has not received much attention from the scientific community. In this paper we will study the Dutch Soccer Team from the perspective of complex networks. In the DST network every node corresponds to a player that has played an official match
Kooij, R.; Jamakovic, A.; Van Kesteren, F.; De Koning, T.; Theisler, I.; Veldhoven, P.
Although being very popular all around the globe, soccer has not received much attention from the scientific community. In this paper we will study the Dutch Soccer Team from the perspective of complex networks. In the DST network every node corresponds to a player that has played an official match
Quality management practices do support the management of strategically important innoυation processes. This conclusion is based on empirical research in the Dutch construction industry. A large-scale innovative construction project is intensively studied during a three-year period. The quality
The aim of this research is to gain insight into the aspects and processes in the Dutch plastic recycling industry which might lead to a preferred customer status and acquiring benefits once the status has been reached. The whole process of reaching preferred customer status goes through various phases in which customer ...
Ravesteijn, W; Kroesen, O
Present-day worldwide water problems require new management tools and sustainable system innovations. At Delft University of Technology research is being carried out into water resources and management development aimed at forming such tools and innovations, focused on Integrated River Basin Management (IRBM). One of the case-studies deals with Dutch water management and technology in the context of European IRBM in the form of the 2000 Water Frame Directive. The Netherlands experience many water problems and European IRBM could bring help by offering a framework for both international cooperation and technological innovations. To work as an adequate management tool European IRBM should be tailored to the Dutch water tradition, which recently culminated in Integrated Water Management. Both approaches are in some respects contradicting. Europe pursues, for example, centralized control; while the Dutch have their strongly water boards based decentralized administration. The tensions between both approaches require mutual adaptation, for which the concept of subsidiarity might offer points of departure. This paper describes the first results of the case-research into Dutch water management and technology in the context of Europe as well as the backgrounds and the set-up of the research as a whole.
Hilte, M.; Bos, M.; Reitsma, P.
Because it is often assumed that difficulties in spelling are of phonological origin, the aim of this study was to examine whether emphasis on the pronunciation of individual graphemes is beneficial for learning to spell words in poor spellers. In the first experiment Dutch children with a spelling
In recent years Dutch real estate developers have been subject to some societal market trends that force them to change roles (Heurkens, 2013). The decreased demand for office space, limited debt funding, challenging user demands, stalling public investments, and increased competition from new
Bekebrede, Judith; van der Leij, Aryan; Plakas, Anna; Share, David; Morfidi, Eleni
This study tested the phonological core deficit hypothesis among Dutch dyslexic adults and also evaluated the pattern of individual differences among dyslexics predicted by the phonological-core variable-orthographic differences (PCVOD) model (van der Leij & Morfidi, 2006) in a sample of 57 control adults and 56 dyslexic adults. It was…
Weijermars, R.; Luthi, S.M.
We highlight a watershed in the natural gas legacy of the Netherlands: after 50 years of successful gas development, production output of conventional fields will decline from 2010 onwards. The projected decline in Dutch gas output will lead to a loss of future income for the State. In the past, E&P
Boesveldt, S.; Verbaan, D.; Knol, D.L.; Hilten, van J.J.; Berendse, H.W.
OBJECTIVES: The aim of the study was to establish normative values for the two culture dependent components (odour identification and odour discrimination) of the "Sniffin' Sticks" test battery in the Dutch population over 45 years of age, and to assess the influence of age and sex on olfactory
The purpose of this thesis was to develop a basic static applied general equilibrium (AGE) model to analyse the effects of agricultural policy changes on Dutch agribusiness. In particular the effects on inter-industry transactions, factor demand, income, and trade are of
Pietola, K.; Oude Lansink, A.G.J.M.
This paper estimates a sequence of energy-saving technology choices by Dutch glasshouse firms. The model allows for time-constant, firm-specific effects and serial correlation of errors and it is estimated on panel data over the period 1991¿1995. The unobserved error sequences are simulated in the
Brand, Alexander; Bollinger, Daan; de Jong, P.; van der Voordt, Theo
Due to structural changes in laws and regulations and ways of financing, Dutch health care organisations are in a phase of reorientation and transition. As such, many strategical issues have to be solved that will influence their corporate real estate strategy. In such a dynamic context real estate
van der Voordt, D.J.M.; Prevosth, J.; van der Zwart, J.
Purpose: To explore if and how Dutch hospital managers steer on adding value by well-considered Facility Management (FM) and Corporate Real Estate Management (CREM), which values are leading, and how adding value is being translated into concrete interventions. Methodology: In addition to a review
Swaan, C.M.; Ouwerkerk, van M.; Roest, H.I.J.
In June 2008, three Dutch tourists participating in a mini-cruise in Turkey needed urgent repatriation for antitoxin treatment because of symptoms of botulism. Because there was a shortage of antitoxin in the Netherlands, an emergency delivery was requested from the manufacturer in Germany. An
Ko, Vinnie; Wieling, Martijn; Wit, Ernst; Nerbonne, John; Krijnen, Wim
Wieling et al. (2011) combined generalized additive modeling (GAM) with mixed-effects regression modeling to identify the influence of social, lexical, and geographical variables on the variation of Dutch dialect pronunciations. The conclusion of their study was that the pronunciation distance from
This article deals with the Dutch and Portuguese-Jewish background of David Ricardo. The important pieces of information, found in the Amsterdam municipal archives, on the one hand correct, and on the other complement, the data presented by P. Sraffa. Recently, new evidence has been found on
Kremer, A.M.; Steenbeek, R.
Introduction Sickness absence has an important impact on employers (e.g. reduced productivity, high costs) and employees (e.g. replacement, job loss). Therefore, we investigated possible reduction by exploring avoidable sickness absence. Methods A questionnaire was filled out by 2,954 Dutch workers
In Dutch fine dining restaurants, the customer who orders a cheeseboard as part of the dessert is served an assortment of cheeses without regard to the dishes that preceded the cheese. The present paper tries to contribute to a more logical order of main dish and cheeseboard. A panel of 12 tasters judged the order of 6 ...
Bosscha Erdbrink, D.P.
Seven fossil specimens, inscribed in five different Dutch collections, are identified as remains of brown bears, Ursus arctos L. Three items are postcranial skeletal parts, two are isolated teeth and two are mandibular fragments. Five fossils have been collected from the North Sea bottom in the
Koper, Jan F.; Bos, Arend F.; Janvier, Annie; Verhagen, A. A. Eduard
AimThis study investigated whether continuous improvements to neonatal care and the legalisation of newborn euthanasia in 2005 had changed end-of-life decisions by Dutch neonatologists. MethodsWe carried out a retrospective study of foetuses and neonates of more than 22weeks' gestation that died in
van der Sijde, Peter; Doornekamp, B.G.
Nowadays, in Dutch secondary education, computer science is integrated within school subjects. About ten years ago computer science was considered an independent subject, but in the mid-1980s this idea changed. In our study we investigated whether the objectives of teaching computer science as an
Os, van E.; Kruijs, A.; Bomas, B.; Poelman, M.; Pater, de M.; Bokhoven, van D.
De blauwalg in het Volkerak - Zoommeer zorgt jaarlijks voor veel overlast. In de zomerperiode zijn giftig water en stank een hinderlijk fenomeen voor iedereen. Met de techniek Dutch Water Mining verdwijnt de overlast van blauwalgen. Voor de omliggende landbouwbedrijven ontstaat de zekerheid van een
Verhoef, Peter C.; Heijnsbroek, Martin; Bosma, Joost
Customer satisfaction is essential for public and railway services, because firms in these industries have contracts with governments requiring them to achieve specific customer satisfaction targets. In this paper, we describe a National Dutch Railways project in which we identify the major
van 't Noordende, G.
In this article, we analyze the security architecture of the Dutch Electronic Patient Dossier (EPD) system. Intended as a national infrastructure for exchanging medical patient records among authorized parties (particularly, physicians), the EPD has to address a number of requirements, ranging from
van 't Noordende, G.
In this article, we analyze the security architecture of the Dutch Electronic Patient Dossier (EPD) system. Intended as a mandatory infrastructure for exchanging medical records of most if not all patients in the Netherlands among authorized parties (particularly, physicians), the EPD has to address
Moon4You is an initiative led by the Dutch Organisation for Applied Scientific Research TNO, with partners from industry and universities in the Netherlands that aims to provide a combined Raman/LIBS instrument as scientific payload for lunar exploration missions, and specifically for Odyssey Moon's
Jacobs, P.; Borsboom, W.A.; Kemp, R.E.J.
Cooking emissions have long been seen as an odour problem. However recent studies showed that Particulate Matter (PM) is the main health risk of indoor air and cooking can be a major source. A small field study within 9 Dutch dwellings indicates that depending on the conditions cooking can have a
Lauwere, de C.C.
It is thought that agricultural entrepreneurs have an important role to play in Dutch agriculture. They are currently being confronted with drastic changes and it is open to question whether or not they are willing and able to deal with such changes. A telephone survey was carried out in order to
Oudenampsen, M.; Kastner, Jens; Birkenstock, Eva; Hinderer Cruz, Max Jorge
“No one is safe.” With these words Halbe Zijlstra, the State Secretary of Education, Culture and Science, announced the slashing of the cultural budget on the Dutch national news in December 2010. Whereas cutbacks are generally accompanied by at least the pretension of reluctance or regret, Zijlstra
Supriatin, Supriatin; Weng, Liping; Comans, Rob N.J.
The study aimed to understand selenium (Se) speciation and extractability in Dutch agricultural soils. Top soil samples were taken from 42 grassland fields and 41 arable land fields in the Netherlands. Total Se contents measured in aqua regia were between 0.12 and 1.97mgkg-1(on average
van Riemsdijk, Maarten; de Leede, Jan
Labour flexibility is a major way for companies to become more flexible. Why companies use flexible labour relations varies widely per industry. We assess the development of labour flexibility within the Dutch automotive industry. Four cases, together representing the production chain, are
Mariia Stolyga; Dr. Martijn de Groot
The Quantified Self Institute (QSI) in Groningen is keeping a close eye on the global self-tracking culture to identify and assess major trends in this domain. How will the future of wearable tech look? Can self-tracking change the Dutch healthcare system? Dr. Martijn de Groot, a medical biologist
Pannekoek, L.; Kooten, van O.; Kemp, R.G.M.; Omta, S.W.F.
This paper focuses on the critical success factors in entrepreneurial innovation, and the role of cooperation with chain partners, knowledge institutions and colleague firms in the Dutch glasshouse industry. This industry, typified by a large number of family-owned entrepreneurial firms, is
This paper will argue that when contemplating the elaboration of a European civil law, Dutch law may have some interesting ideas to offer. From the wealth of thoughts offered by the General Reporter, only one particular thread will be taken up in depth. It is the protection of the weaker contracting
This paper summarizes the findings of a four-pronged research project concerning the behavior of Dutch divorce lawyers, in which lawyers, judges, and clients were interviewed and lawyer-client interaction directly observed. In the first part, some preliminary remarks are made on the practical and
Carballo-Cárdenas, Eira C.; Tobi, Hilde
Understanding the drivers and barriers to participation in citizen science initiatives for conservation is important if long-term involvement from volunteers is expected. This study investigates the motivations of individuals from five marine protected areas (MPAs) in the Dutch Caribbean to (not)
Jerkovic, K.; van Offenbeek, M.A.G.; van der Schans, C.P.
Objectives: This study compares the scope of practice of Dutch dental hygienists (DHs) educated through a 2- or 3-year curriculum ('old-style DHs') with that of hygienists educated through a new extended 4-year curriculum leading to a bachelor's degree ('new-style DHs'), with the aim to investigate
Hong, T.M.; Pieke, F.N.; Steehouder, L.; Veldhuizen, van J.L.
The number of Chinese students in the Dutch higher education sector has grown rapidly. In 2014 the number of Chinese BA and MA students reached 4638, or about 7 percent of the population of international students in the Netherlands. The number of formally employed PhD students in that year was 427.
Duineveld, C.; Vroegop, M.; Schouren, L.; Hoedemaekers, A.; Schouten, J.A.; Moret-Hartman, M.; Kramers, C.
CONTEXT: Acute intoxications are frequently seen in Dutch hospitals. Based on single-centre studies and the fact that there are no clear guidelines, we hypothesised that hospital admission of acute intoxications may vary. Furthermore, decontamination treatment of poisonings may differ between