Sample records for national fertilizer development

  1. Tunisia: high fertility stalls development. (United States)

    Barberis, M


    Despite government policy enacted in 1964 to reduce fertility in order to hasten socioeconomic progress, population pressures continue to impair development in Tunisia. The birth rate fell 20% over the last 2 decades, but this accomplishment has been outweighed by a 50% decline in mortality rates. As a result, the rate of natural population increase has remained relatively constant at 2.5%/year. The initial decline in fertility that followed introduction of the national family planning program appears to have reached a plateau, explained in part by the resurgence of conservatism and religious fundamentalism and the consequent emphasis on women's childbearing roles. Unemployment in rural areas has led to widespread migration and unemployment is as high as 20% in the nonagricultural sector. Many young Tunisians lack adequate educational preparation to enter the labor force; in 1982, 27% of new job entrants could not read or write. The government's plan to decentralize development to stabilize population and achieve equilibrium between regions has been thwarted by the pace of population growth and limited resources. The rural regions where population is increasing the fastest are also the most difficult to reach with family planning programs. On the other hand, there have been some successes in this area when services have been adapted to the lifestyle and traditions of those in these isolated rural villages.

  2. Tennessee Valley Authority National Fertilizer and Environmental Research Center

    International Nuclear Information System (INIS)

    Gautney, J.


    The National Fertilizer and Environmental Research Center (NFERC) is a unique part of the Tennessee Valley Authority (TVA), a government agency created by an Act of Congress in 1933. The Center, located in Muscle Shoals, Alabama, is a national laboratory for research, development, education and commercialization for fertilizers and related agricultural chemicals including their economic and environmentally safe use, renewable fuel and chemical technologies, alternatives for solving environmental/waste problems, and technologies which support national defense- NFERC projects in the pesticide waste minimization/treatment/disposal areas include ''Model Site Demonstrations and Site Assessments,'' ''Development of Waste Treatment and Site Remediation Technologies for Fertilizer/Agrichemical Dealers,'' ''Development of a Dealer Information/Education Program,'' and ''Constructed Wetlands.''

  3. Development of the knowledge of fertility and fertility preservation scale

    Directory of Open Access Journals (Sweden)

    McNees P


    Full Text Available Angela Jukkala1, Karen Meneses1, Andres Azuero1, June Cho1, Patrick McNees1,21School of Nursing, 2School of Health Professions, University of Alabama at Birmingham, Birmingham, AL, USAObjective: Infertility is a severe and often underestimated consequence of successful treatment for breast cancer. Ensuring young breast cancer survivors receive patient-centered health information on the impact of treatment on fertility and fertility preservation options in a timely manner is a critical component of high quality nursing care. The objective of this manuscript is to report the process used to develop and examine the reliability and validity of an instrument to measure a breast cancer survivor’s self-assessed knowledge of fertility and fertility preservation.Design: A scale development and descriptive study.Setting: Online and global.Participants: Ninety-two young breast cancer survivors (ages 25–45 years.Methods: Participants completed the Knowledge of Fertility and Fertility Preservation (KF Scale as part of their participation in a larger study, the Fertility Cancer Project (FCP.Results: An exploratory factor analysis revealed five domains: normal reproductive function; general information about fertility; cancer treatment factors affecting fertility; infertility information; and alternative parenting options. A confirmatory factor analysis confirmed the validity of the construct with a demonstrated good fit between the factor structure of the new scale and the observed data. Many participants self-assessed their overall knowledge of fertility and fertility preservation as “a little” and the majority rated their knowledge of infertility information as “a little”.Conclusion: The KF Scale can be used to provide useful information to support health care professionals in the development of patient-centered education that is responsive to the unique needs of each young breast cancer survivor. The initial testing of the KF Scale indicates

  4. Regulation of fertilization and early seed development. (United States)

    Dresselhaus, Thomas; Doughty, James


    Plant reproduction meetings often deal either with pre-fertilization processes such as flowering and pollen biology or post-fertilization processes such as embryogenesis and seed development. The Biochemical Society Focused Meeting entitled 'Regulation of Fertilization and Early Seed Development' was organized to close this gap and to discuss mechanistic similarities and future research directions in the reproductive processes shortly before, during and after fertilization. As an outcome of the workshop, invited speakers and a few selected oral communication presenters contributed focused reviews and technical articles for this issue of Biochemical Society Transactions. We provide here a short overview of the contents and highlights of the various articles.

  5. Intergenerational fertility correlations in contemporary developing counties. (United States)

    Murphy, Michael


    To estimate the magnitude of intergenerational continuities in total and effective fertility among women in a group of 46 contemporary developing countries. Information collected from 93,000 women aged 45-49 for estimation of maternal mortality in the demographic and health surveys (DHS) program is analyzed using Pearson product moment intergenerational fertility correlations. A positive but usually small intergenerational correlation is found for both completed fertility (CFS, total number of children born) and effective fertility (EFS, number of children surviving to age of reproduction). Although the developing countries are mainly located in sub-Saharan Africa, a similar pattern appears to hold for the Asian and Latin American countries included. Women in the second generation with no education have a stronger relationship with their parents' fertility than women with some education. The relationship is also stronger in rural than in urban areas and in countries with lower levels of development. Intergenerational correlations of completed fertility in both generations are marginally stronger than for effective fertility largely because the number of a woman's total sibs is more strongly related to her subsequent childbearing than her number of adult sibs. Values of intergenerational correlations for these countries are similar to published values for a number of Western pretransitional populations, but well below values in contemporary developed societies. Copyright © 2012 Wiley Periodicals, Inc.

  6. Oil-exporting status, quality of life, and fertility: a cross national study. (United States)

    Hunter, S R; Stokes, C S; Warland, R H


    It has been suggested that unless the rapid increase in income in the oil-exporting countries is accompanied by more equitable distribution of modern goods and services, the impact on health, literacy, and fertility is likely to be negligible. This study represents an initial attempt to examine the possible effects of the oil-exporting status of nations on their income, quality of life, and fertility. Data from 150 countries were used, and the Physical Quality of Life Index (PQLI) was utilized instead of traditional measures of development. Some findings are: 1) the variable showing the strongest direct relationship to fertility was physical quality of life (p=-.756) which is consistent with the distributional hypothesis; 2) per capita gross national product (GNP) and oil-exporting status showed weaker paths to fertility and their signs were in opposite directions; 3) per capita GNP showed a moderate negative relationship to fertility (p=-.171) while oil-exporting status had a positive path of about the same size (p= .155), thus per capita income and oil-exporting status had only about 1/5 the net relationship to fertility as did physical quality of life; 4) the indirect relationship of income as channeled through PQLI was over twice as large as the measured direct relationship, so that the importance of per capita GNP for lower fertility is primarily through its influence on the physical quality of life within a nation; 5) oil-exporting status was associated with lower physical quality of life and the latter was strongly related to higher fertility; and 6) in the long run, the relationship between oil-exporting status and quality of life should be positive. If separate analyses are conducted, the division should be made along an oil-exporter/non-exporter dichotomy, rather than a more developed/less developed country categorization. It is concluded that nations with relatively high life expectancies high levels of literacy, and low levels of infant mortality

  7. Marriage and fertility in the developed countries. (United States)

    Westoff, C F


    Most developed countries have reached zero population growth or less and, while population projections have often proved badly off-target, it seems that currently low fertility levels are the result of a long-term trend, which was interrupted in the last 100 years only by the still-unexplained postwar baby boom, and which will probably continue. The declining trend has accompanied economic development and modernization, which have transformed the economic value of children, making them a drain on resources rather than a source of income. The concomitant social changes seem largely irreversible: urban economy, the decline in traditional authority, universal, prolonged education, equality of women, low infant mortality, high consumer demands and sophisticated birth control technology are all here to stay. The theory that fertility exhibits a cyclical pattern based on people's perception of their degree of economic and social opportunity ignores the other elements affecting fertility behavior, especially the radical change in the status and expectations of women. Several trends in marriage and reproductive behavior in the U.S., Denmark and Sweden reinforce the presumption that fertility will remain low: declining number of marriages; postponement of marriage; increased tendency for unmarried couples to live together; instability of marriage shown by high divorce rates and declining remarriage rates; and increasing economic activity by women. The traditional institution of marriage is losing its economic, sexual, sociological and parenting rationales. Thus, declining fertility is both cause and consequence of changes in marriage. In Europe, where the decline is more advanced than in the U.S., governments are concerned that population growth will be too low and have instituted social welfare measures to induce and facilitate childbearing and childrearing. As women become more career-oriented, greater incentives will have to be provided. Manipulating immigration quotas

  8. Fertilizer application and root development analyzed by neutron imaging

    International Nuclear Information System (INIS)

    Nihei, Naoto; Tanoi, Keitaro; Nakanishi, Tomoko M.


    We studied the development of the soybean root system under different application of fertilizer applying neutron imaging technique. When neutron beam was irradiated, the root image as well as fertilizer imbedded in a thin aluminum container was clearly projected, since water amount in roots are higher than that in soil. Through image analysis, the development of root system was studied under different application of the fertilizer. The development of a main root with lateral roots was observed without applying fertilizer. When the fertilizer was homogeneously supplied to the soil, the morphological development of the root showed the similar pattern to that grown without fertilizer, in different to the amount of the fertilizer. In the case of local application of the fertilizer, lateral position or downward to the main root, the inhibition of the root growth was observed, suggesting that the localization of the fertilizer is responsible for reduction of the soybean yield. (author)

  9. China's below-replacement fertility: government policy or socioeconomic development? (United States)

    Cai, Yong


    The article challenges the notion that below-replacement fertility and its local variation in China are primarily attributable to the government's birth planning policy. Data from the 2000 census and provincial statistical yearbooks are used to compare fertility in Jiangsu and Zhejiang, two of the most developed provinces in China, to examine the relationship between socioeconomic development and low fertility. The article demonstrates that although low fertility in China was achieved under the government's restrictive one-child policy, structural changes brought about by socioeconomic development and ideational shifts accompanying the new wave of globalization played a key role in China's fertility reduction.


    Directory of Open Access Journals (Sweden)

    Gabriela SIMIONESCU


    Full Text Available This review summarizes aspects regarding the national program for in vitro fertilization and embryo transfer in Romania, emphasizing on the ethical, legal and social challenges associated with assisted reproduction technologies. Romania is one of the few countries from the European Union that does not have a specific law for human assisted reproduction, but infertile couples in Romania may benefit from the national program for in vitro fertilization and embryo transfer although, unfortunately, the allocated public funds are not in line with the demand. There are a series of inclusion criteria when applying for the program and unlike other countries, only one in vitro fertilization (IVF procedure may be publicly funded. Despite the legal, ethical and social challenges, this program, however, represents an extremely important step in aligning our country with the standards of other developed countries.

  11. Fertility and Population Policy


    Ouedraogo, Abdoulaye; Tosun, Mehmet S.; Yang, Jingjing


    There have been significant changes in both the fertility rates and fertility perception since 1970s. In this paper, we examine the relationship between government policies towards fertility and the fertility trends. Total fertility rate, defined as the number of children per woman, is used as the main fertility trend variable. We use panel data from the United Nations World Population Policies database, and the World Bank World Development Indicators for the period 1976 through 2013. We find...

  12. Endogenous fertility and development traps with endogenous lifetime


    Fanti, Luciano; Gori, Luca


    We extend the literature on endogenous lifetime and economic growth by Chakraborty (2004) and Bunzel and Qiao (2005) to endogenous fertility. We show that development traps due to underinvestments in health cannot appear when fertility is an economic decision variable and the costs of children are represented by a constant fraction of the parents' income used for their upbringing.

  13. Oviduct: roles in fertilization and early embryo development. (United States)

    Li, Shuai; Winuthayanon, Wipawee


    Animal oviducts and human Fallopian tubes are a part of the female reproductive tract that hosts fertilization and pre-implantation development of the embryo. With an increasing understanding of roles of the oviduct at the cellular and molecular levels, current research signifies the importance of the oviduct on naturally conceived fertilization and pre-implantation embryo development. This review highlights the physiological conditions within the oviduct during fertilization, environmental regulation, oviductal fluid composition and its role in protecting embryos and supplying nutrients. Finally, the review compares different aspects of naturally occurring fertilization and assisted reproductive technology (ART)-achieved fertilization and embryo development, giving insight into potential areas for improvement in this technology. © 2017 Society for Endocrinology.

  14. Sea urchin egg fertilization and development (United States)

    Young, R. S.


    The effects of subgravity (much less than unit gravity) on fertilization, cell division, differentiation, and growth of a relatively simple biological system (eggs of the sea urchin Arbacia punctulata) were considered. The experiment was flown on Gemini 3 and recovered as scheduled. However, the experiment objectives were not achieved, primarily for mechanical reasons.

  15. Development of Malaysian women fertility index: Evidence from Shannon's entropy (United States)

    Jalil, Wan Aznie Fatihah Wan Abd; Sharif, Shamshuritawati


    A fertility rate is a measure of the average number of children a woman will have during her childbearing years. Malaysia is now facing a population crisis and the fertility rate continues to decline. This situation will have implications for the age structure of the population where percentages of senior citizens are higher than percentages of people aged below 5 years old. Malaysia is expected to reach aging population status by the year 2035. As the aging population has a very long average life expectancy, the government needs to spend a lot on medical costs for senior citizens and need to increase budgets for pensions. The government may be required to increase tax revenues to support the growing older population. The falling fertility rate requires proper control by relevant authorities, especially through planning and implementation of strategic and effective measures. Hence, this paper aims to develop a fertility index using Shannon's entropy method. The results show that Selangor, Johor, and Sarawak are among the states with the highest values of the fertility index. On the other end of the spectrum, Terengganu, W.P. Labuan, and Perlis are ranked in the last positions according to the fertility index. The information generated from the results in this study can be used as a primary source for the government to design appropriate policies to mitigate dwindling fertility rates among Malaysian women.

  16. Fertility behavior in developing economies: an investment approach. (United States)

    Chernichovsky, D


    By studying intergenerational benefits from children, this paper shows that the economic analysis of fertility behavior in developing economics can provide a systematic discussion of this behavior. The major hypotheses set forth are: 1) the effect of income on fertility depends on the source and timing of income; 2) in a lifetime context, parents, or would-be parents, who have higher incomes at young ages compared with the income they anticipate at old age, are expected to have a higher demand for children; and 3) the reverse of the latter is predicted for parents who anticipate relatively higher incomes at old age. These hypotheses follow the idea that, in the absence of other appropriate means for intertemporal transfers of wealth, parents even out the lifetime welfare through fertility behavior. Under these circumstances, fertility rates are expected to increase in communities where children abandon their traditional commitments to their aging parents, as may happen during periods of economic and cultural transition. A decline in mortality rates will induce lower fertility. This model suggests that a tax-financed social security scheme along with family planning will be conducive to a reduction in fertility. A test on data from an Indian village in 1968-69 suggests that in a traditional setting there is a correlation between household welfare, measured by income or assets, and the presence of grown children. Income has a positive effect on fertility when the parents' incomes comes from labor rather than human and nonhuman capital which provides income at later stages of life. Longitudinal data depicting income, savings, and fertility patterns over time should prove more promising in exploring the issues discussed.

  17. Fertilization and Embryo Development of Fresh and Cryopreserved Sibling Oocytes

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    Robert F. Casper


    Full Text Available Background: Oocyte cryopreservation is potentially the best way to preserve female fertility forunmarried women or young girls at risk of losing ovarian function. The aim of this study was tocompare fertilization and embryo development in frozen-thawed oocytes to their fresh siblings inwomen undergoing in vitro fertilization (IVF and embryo transfer (ET.Materials and Methods: Eleven infertile women undergoing infertility treatment, between theages of 24 to 37 years (mean ± SD = 31.6 ± 3.5, were included in this study. Mature oocytesfrom each patient were randomized into cryopreserved and fresh groups prior to intracytoplasmicsperm injection (ICSI. One hundred and thirty nine oocytes were retrieved, of which 105 were atmetaphase II (MII. Forty- five fresh MII oocytes were kept in culture whereas their sibling 60 MIIoocytes were cryopreserved using a slow cooling protocol. The frozen oocytes remained in LN2for 2 hours before thawing. ICSI was performed 1-2 hours after thawing for frozen oocytes and 4-5hours after retrieval for fresh oocytes. Fertilization and embryo development were compared.Results: Following thawing, 31 oocytes (51.6 % survived and 22 fertilized (79% while 32 freshoocytes fertilized upon ICSI (71%. The mean ± SE scores for embryos developing from frozenthawedoocytes were significantly lower at 48 and 72 hours post-ICSI than for embryos resultingfrom fresh oocytes (p<0.05.Conclusion: Our data demonstrated that oocyte freezing resulted in acceptable survival ratesfollowing cryopreservation, and similar fertilization rates following ICSI as compared to the freshsibling oocytes. However the number of blastomeres and the embryo quality on day three wassuperior in embryos from fresh oocytes when compared to the frozen oocytes.

  18. Global Phosphorus Fertilizer Market and National Policies: A Case Study Revisiting the 2008 Price Peak. (United States)

    Khabarov, Nikolay; Obersteiner, Michael


    The commodity market super-cycle and food price crisis have been associated with rampant food insecurity and the Arab spring. A multitude of factors were identified as culprits for excessive volatility on the commodity markets. However, as it regards fertilizers, a clear attribution of market drivers explaining the emergence of extreme price events is still missing. In this paper, we provide a quantitative assessment of the price spike of the global phosphorus fertilizer market in 2008 focusing on diammonium phosphate (DAP). We find that fertilizer market policies in India, the largest global importer of phosphorus fertilizers and phosphate rock, turned out to be a major contributor to the global price spike. India doubled its import of P-fertilizer in 2008 at a time when prices doubled. The analysis of a wide set of factors pertinent to the 2008 price spike in phosphorus fertilizer market leads us to the discovery of a price spike magnification and triggering mechanisms. We find that the price spike was magnified on the one hand by protective trade measures of fertilizer suppliers leading to a 19% drop in global phosphate fertilizer export. On the other hand, the Indian fertilizer subsidy scheme led to farmers not adjusting their demand for fertilizer. The triggering mechanism appeared to be the Indian production outage of P-fertilizer resulting in the additional import demand for DAP in size of about 20% of annual global supply. The main conclusion is that these three factors have jointly caused the spike, underscoring the need for ex ante improvements in fertilizer market regulation on both national and international levels.

  19. Factors affecting the development of in vitro fertilization in camelids

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    Trasorras VL


    Full Text Available In any program of in vitro embryo production, the ultimate goal is to develop high quality embryos being able to get a normal pregnancy and finally resulting in the birth of a healthy offspring, goal not reach yet in camelids. The application of assisted reproductive techniques, such as in vitro fertilization and subsequent in vitro embryo culture, can extend the knowledge of early embryonic development and make possible the increase of the population of genetically superior animals.

  20. Fertilizer Reduction Policies in Developed Countries: Suitability and Implications

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    LI Fang


    Full Text Available This study reviewed and analyzed the specific practices, implementation effects and applicable conditions of fertilizer reduction policies in the EU, US and Japan, explored the common laws and general conditions in the formulation of environmental orientation, and pro vided feasible policy recommendations for the formulation of fertilizer reduction policies in China. This study showed that fertilizer reduction policies in each country had their own advantages and disadvantages, and the applicable conditions were different. The EU's command and control policy was applicable to the situation of less farm households and the same agricultural planting type or farm type. The economic in centive policy in the US was applicable to the situation of more farm households, relatively perfect agricultural market system and sensitive price formation mechanism, while the public participation policy in Japan was applicable to regions with more relevant agricultural groups and strong economy. China should learn from each of these policies and make a comprehensive choice in the formulation of fertilizer reduc tion policies. Therefore, China should proceed from improving the agricultural price mechanism and the pollution-free agricultural products certification system as well as encouraging and supporting the development of large scale production units, and then promote the adoption of environmentally friendly technology through the guidance of market mechanism, ensure the effective implementation of environmental stan dards through farmers' integration and improve farmers' environmental awareness through propaganda guidance, so as to ensure the effective implementation of different types(command and control policy, economic incentive policy and public participation policyof fertilizer reduc tion policies.

  1. Aspects of psychosocial development in infertile versus fertile men. (United States)

    Akhondi, Mohammad Mehdi; Binaafar, Sima; Ardakani, Zohreh Behjati; Kamali, Kourosh; Kosari, Haleh; Ghorbani, Behzad


    Infertility is one of the most difficult life experiences that a couple might encounter. Infertility as a bio-psycho-social phenomenon, could influence all aspects of life. While paying special attention to the psychological aspects of infertility in couples; many studies have investigated the non-clinical aspects of infertility, however, they rarely have evaluated the psychosocial development of infertile versus fertile men. We aimed to study the effects of infertility on psychosocial development in men. In fact, we designed the study based on "Erikson's theory of psychosocial development". We focused on the relationship between psychosocial development and some self-conceived indices. For this purpose, we divided the participants volunteers into two groups of cases (80 infertile men) and controls (40 fertile men) and asked them to complete a 112 (questions questionnaire based on "self description"). The statistical analysis was performed by SPSS (version 13) using independent t-test, Pearson correlation coefficient and analysis of covariance. A p-value stages (p stages. Infertility as a phenomenon had its own effects on the psychosocial development of infertile men. However, good coping skills are powerful tools to manage these myriad of feelings surrounding infertile men.

  2. Decision on Fertility Preservation in Cancer Patients: Development of Information Materials for Healthcare Professionals. (United States)

    Silva, Cristina; Almeida-Santos, Ana Teresa; Melo, Cláudia; Rama, Ana Cristina Ribeiro


    Infertility is a potential side effect of cancer chemotherapy. As the number of adolescent and young adult (AYA)-aged survivors increases, future fertility becomes an important issue. However, many patients are not adequately informed and oncologists point the lack of information as a barrier to discussion. Our aim was to produce information materials tailored to oncologists' needs to promote and support discussion on infertility risk and fertility preservation (FP) with AYA-aged patients. After literature review, information materials were successfully developed and are currently being distributed to healthcare professionals in Portugal, with the collaboration of several national organizations. These information materials will contribute to shared informed decisions regarding FP in AYA-aged patients.

  3. Development of a Semi-controller for a Variable Rate Fertilizer Applicator (United States)

    Ji, Jianbin; Wang, Xiu; Mao, Yijin; Chen, Liping; Hu, Lingyan

    In this paper, aiming at the current development of domestic agricultural production, introduced a variable fertilizer controller which suits for a domestic food-producing areas to promote output. The variable rate fertilization controller combined with the current Chinese made fertilizer equipment; mechanism of metering system for the applicator uses a flute wheel. The amount of fertilizer is determined by the rotation speed of flute wheel. The use of the control system can be inconsistent in soil fertility, pre-division of plots with different fertilizer way through the process of moving the driver automatically adjusts the amount of fertilizer direction buttons to precision variable fertilization. Papers on the electronic structure of the controller and software design in detail. In addition, we have examined the performance of this new product in the field by using different fertilizer and requirement. The results reveal that semi-automatic controller work well by controlling the quantity of fertilizer precisely. Specifically, coefficient of variation of fertilizing is controlled to be less than 5%. That means this new type semi-automatic controller worth developing in further.

  4. Rural Community Development: Bedrock for National Development ...

    African Journals Online (AJOL)

    This paper advocates that community development is the bedrock for national development. For any meaningful development to take place, whether national or global development must have its building blocks or firm-root in rural development. However, the rural communities are characterized by isolation from ideas and ...

  5. Global Fertilizer and Manure, Version 1: Nitrogen Fertilizer Application (United States)

    National Aeronautics and Space Administration — The Nitrogen Fertilizer Application dataset of the Global Fertilizer and Manure, Version 1 Data Collection represents the amount of nitrogen fertilizer nutrients...

  6. Global Fertilizer and Manure, Version 1: Phosphorus Fertilizer Application (United States)

    National Aeronautics and Space Administration — The Phosphorus Fertilizer Application dataset of the Global Fertilizer and Manure, Version 1 Data Collection represents the amount of phosphorus fertilizer nutrients...

  7. Fertilizer-N use efficiency and nitrate pollution of groundwater in developing countries (United States)

    Singh, Bijay; Singh, Yadvinder; Sekhon, G. S.


    Around 76% of the world's population lives in developing countries where more fertilizer-N is currently applied than in developed countries. Fertilizers are applied preferentially in regions where irrigation is available, and soil and climatic conditions are favorable for the growth of crop plants. Due to low N application rates during the last 3 or 4 decades, negative N balances in the soil are a characteristic feature of the crop production systems in developing countries. In the future, with increasing fertilizer-N application rates, the possibility of nitrate pollution of groundwater in developing countries will be strongly linked with fertilizer-N use efficiency. A limited number of investigations from developing countries suggest that, in irrigated soils of Asia or in humid tropics of Africa, the potential exists for nitrate pollution of groundwater, especially if fertilizer-N is inefficiently managed. In a large number of developing countries in West and Central Asia and North Africa, the small amount of fertilizer applied to soils (mostly Aridisols) that remain dry almost all the year, do not constitute a major threat for nitrate pollution of groundwater, except possibly when soils are irrigated. In Asia and the Pacific regions, where 70% of the fertilizers are used to grow wetland rice on soils with low percolation rates, leaching of nitrates is minimal. Climatic water balance and soil moisture conditions do not favor leaching of nitrates from the small amount of fertilizer-N applied to Oxisols and Ultisols in Latin America. In developing countries located in the humid tropics, attempts have not been made to correlate fertilizer-N use with nitrate level in groundwater; however, fertilizers are being increasingly used. Besides high rainfall, irrigation is becoming increasingly available to farmers in the humid tropics and substantial leaching of N may also increase.

  8. Effect of fertilization regime on nutrient and plankton development in ...

    African Journals Online (AJOL)

    Groups of three such ponds measuring 9 x4x1.5m each were fertilized with chicken droppings (to obtain higher quantities of phosphorus) (treatment 1) and organic matter (to obtain higher levels of organic matter) (treatment 2). Composite water and sediment samples were collected weekly from transects of the reservoir, ...

  9. Effects of organic fertilizers on growth and development of pepper (Capsicum annuum L.

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    Ricardo Augusto Luna Murillo


    Full Text Available Organic fertilizers are biofertilizers for crop treatment as activators of the physiologic functions, so that its application makes better use of nutrients and represent an appropriate option to address the pro-blems of chemical fertilization. The objective of the present study was to determine the effect of two organic fertilizers on the growth and development of pepper plants, which were subjected to different doses of these fertilizers in a completely randomized design with five repetitions. The work was developed in the Experimental Center “The Beach”, belonging to the Technical University of Cotopaxi, extension La Maná. The stem length, number of fruits, fruit diameter, and fresh biomass of the fruit were measured. The results showed that the pepper plants with the application of organic fertilizers stimulated the variables height of the plant, number of fruits, long of the fruit, diameter of the fruits and fresh biomass of the fruits

  10. An Agent-Based Dynamic Model of Politics, Fertility and Economic Development


    Zining Yang


    In the political economy of development, government policy choices at a single point in time can dramatically affect a country's development path by impacting fertility, economic and political decisions across generations. Combining system dynamics and agent-based modeling approaches in a complex adaptive system, a simulation framework of the Politics of Fertility and Economic Development (POFED) is formalized to understand the relationship between politics, economic, and demography change at...

  11. Fertilizing growth: Agricultural inputs and their effects in economic development. (United States)

    McArthur, John W; McCord, Gordon C


    This paper estimates the role of agronomic inputs in cereal yield improvements and the consequences for countries' processes of structural change. The results suggest a clear role for fertilizer, modern seeds and water in boosting yields. We then test for respective empirical links between agricultural yields and economic growth, labor share in agriculture and non-agricultural value added per worker. The identification strategy includes a novel instrumental variable that exploits the unique economic geography of fertilizer production and transport costs to countries' agricultural heartlands. We estimate that a half ton increase in staple yields generates a 14 to 19 percent higher GDP per capita and a 4.6 to 5.6 percentage point lower labor share in agriculture five years later. The results suggest a strong role for agricultural productivity as a driver of structural change.

  12. Has Culture Fulled the Great Fertility Decline in Developing Countries since 1960?

    DEFF Research Database (Denmark)

    Wang, Cong; Madsen, Jakob; Moslehi, Solmaz

    This paper suggests that secularization is one of the driving forces behind the great fertility decline that developing countries are currently undergoing. While large families are valued in gender-stratified and collectivist societies, individualistic and secular societies emphasize gender...

  13. Fertility of Czech Females Could Be Lower than Expected: Trends in Future Development of Age-Specific Fertility Rates up to the Year 2050

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    Ondřej Šimpach


    Full Text Available Fertility is an essential aspect of reproduction or population replacement of each country. The challenge for demographers is to model fertility and also to estimate its potential future level for the purposes of population projections. In the case of the Czech Republic we have the population projections provided by the Czech Statistical Office (CZSO with overlooking of the total fertility rate in low, medium and high variant. These estimates despite being based on expert judgments, seem to be too positive compared to the past development of the time series of age-specific fertility rates. The aim of this paper is to assess the situation of fertility in the Czech Republic, to analyse the past development of the time series of age-specific fertility rates using one-dimensional Box-Jenkins models and multidimensional stochastic Lee-Carter approach. Together with found trend in time series and principal components estimated by Lee-Carter’s model a forecasts of age-specific fertility rates up to the year 2050 is constructed. Th ese rates are lower than those provided by CZSO in its three variants of the Czech Republic’s population projection, and therefore we discuss the causes at the end of the paper. We would like to point out that the potential future development of Czech females fertility could be lower than which are currently expected.

  14. Lower fertility associated with obesity and underweight: the US National Longitudinal Survey of Youth. (United States)

    Jokela, Markus; Elovainio, Marko; Kivimäki, Mika


    It has been hypothesized that body weight predicts the number of children that a person will have: obese and underweight persons are hypothesized to have fewer children than do their normal-weight counterparts. We aimed to prospectively examine the association between body weight in young adulthood and achieved fertility in later life. A representative national sample of 12 073 American young adults (aged 17-24 y in 1981) were followed through 2004 (19 survey waves of the National Longitudinal Survey of Youth). Obese young women and men were less likely to have their first child by the age of 47 y than were their normal-weight counterparts [relative risk (RR) = 0.69; 95% CI: 0.61, 0.78 in women; RR = 0.75; 95% CI: 0.66, 0.84 in men). Obesity also predicted a lower probability of having more than one child, particularly for women. These associations were partly explained by a lower probability that obese participants will marry. Underweight men were less likely to have the first, second, third, and fourth child than were normal-weight men (RRs = 0.75-0.88; 95% CIs: 0.61, 0.95). These associations were largely explained by the lower marriage probability of underweight men. Obese women and men and underweight men were less likely to have as many children in adulthood as they had desired as young adults. Obesity may be an important risk factor for lower fertility because of its social and possibly biological effect on reproductive behavior. Further data are needed to assess whether this association holds in more recent cohorts.

  15. Evaluation of Protective Effects of Crocin Onembyo Developing Process in in Vitro Fertilization (IVFin Cyclophosphamide Treated Mice

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    F Khan Mohammadi


    Conclusion: The co-administration of crocin with CP chemotherapy caused a significant improvement in fertilizing potential and promoted the embryo development. Key words: Cyclophosphamide, Crocin, Mice, Oocyte, In vitro fertilizing

  16. Fertilization 2: Polyspermic Fertilization. (United States)

    Mizushima, Shusei


    During fertilization in animals, a haploid egg nucleus fuses with a haploid sperm nucleus to restore the diploid genome. In most animals including mammals, echinoderms, and teleostei, the penetration of only one sperm into an egg is ensured at fertilization because the entry of two or more sperm is prevented by polyspermy block systems in these eggs. On the other hand, several animals such as birds, reptiles, and most urodele amphibians exhibit physiological polyspermy, in which the entry of several sperm into one egg is permitted. However, in these polyspermic eggs, only one sperm nucleus is involved in zygotic formation with a female nucleus, thereby avoiding syngamy with multiple sperm nuclei. In the chicken, 20-60 sperm are generally found within the egg cytoplasm at fertilization and this number is markedly higher than that of other polyspermic species; however, avian-specific events such as the degeneration and mitosis of supernumerary sperm nuclei during early embryo development allow a polyspermic egg to develop normally. This chapter describes current knowledge on polyspermy-related events in avian eggs during fertilization, and is characterized by a comparison to the fertilization modes of other vertebrates. The close relationship between sperm numbers and egg sizes, and the movement of supernumerary sperm nuclei towards the periphery of the egg cytoplasm and their degeneration are summarized. The molecular mechanisms by which polyspermy initiates egg activation to start embryo development are also discussed.

  17. Loss of Bmal1 decreases oocyte fertilization, early embryo development and implantation potential in female mice. (United States)

    Xu, Jian; Li, Yan; Wang, Yizi; Xu, Yanwen; Zhou, Canquan


    Biological clock genes expressed in reproductive tissues play important roles in maintaining the normal functions of reproductive system. However, disruption of female circadian rhythm on oocyte fertilization, preimplantation embryo development and blastocyst implantation potential is still unclear. In this study, ovulation, in vivo and in vitro oocyte fertilization, embryo development, implantation and intracellular reactive oxygen species (ROS) levels in ovary and oviduct were studied in female Bmal1+/+ and Bmal1-/- mice. The number of naturally ovulated oocyte in Bmal1-/- mice decreased (5.2 ± 0.8 vs 7.8 ± 0.8, P fertilization rate and obtained blastocyst number were observed in Bmal1-/- female mice either mated with wild-type in vivo or fertilized by sperm from wild-type male mice in vitro (all P fertilization rate of oocytes derived from Bmal1-/- increased significantly compared with in vivo study (P fertilization rate, early embryo development and implantation potential in female mice, and these may be possibly caused by excess ROS levels generated in ovary and oviduct.

  18. Medicinal Plants: A Prospect in Developing Male Fertility Enhancing Agent

    Directory of Open Access Journals (Sweden)

    Muhammad Ja’far Luthfi


    Full Text Available Medicinal plants have been a revolutionary breakthrough in the treatment of male sexual dysfunction. Traditional medicine based on a holistic philosophy is quite different with the practice of “western” medicine. Phytochemical substances focus their mechanisms of healing to the root of cause, i.e. the inability of controlling the proper function of the whole body system. Hence, medicinal plants manage sexual dysfunction and male fertility in the frame of sexual dysfunction as a whole entity. Some previous researches prove that the use of medicinal plants have a good impact in the treatment of a variety of male sexual problems. This paper will discuss several important aspects of aphrodisiac plants and preliminary study regarding them in Indonesia. Difficulties inherent to activity guided isolation and the specific requirements of bioassays are also discussed.

  19. The intergenerational transmission of divorce in cross-national perspective: Results from the Fertility and Family Survey




    Published online: 20 Oct 2008 We used data on women's first marriages from the Fertility and Family Surveys to analyse the intergenerational transmission of divorce across 18 countries and to seek explanations in macro-level characteristics for the cross-national variation. Our results show that women whose parents divorced have a significantly higher risk of divorce in 17 countries. There is some cross-national variation. When compared with the USA, the association is stronger in six coun...

  20. Measuring male fertility rates in developing countries with Demographic and Health Surveys: An assessment of three methods

    Directory of Open Access Journals (Sweden)

    Bruno Schoumaker


    Full Text Available Background: Levels and patterns of male fertility are poorly documented in developing countries. Demographic accounts of male fertility focus primarily on developed countries, and where such accounts do exist for developing countries they are mainly available at the local or regional level. Objective: We show how data from Demographic and Health Surveys (DHS can be used to compute age-specific male fertility rates. Three methods are described and compared: the own-children method, the date-of-last-birth method, and the crisscross method. Male and female fertility rates are compared using the own-children method. Results: Male fertility estimates produced using the own-children method emerge as the most trustworthy. The data needed for this method is widely available and makes it possible to document male fertility in a large number of developing countries. The date-of-last-birth method also appears worthwhile, and may be especially useful for analyzing fertility differentials. The crisscross method is less reliable, but may be of interest for ages below 40. Comparisons of male and female fertility show that reproductive experiences differ across gender in most developing countries: Male fertility is substantially higher than female fertility, and males have their children later than females. Contribution: This study shows that Demographic and Health Surveys constitute a valuable and untapped source of data that can be used to document male fertility in a large number of countries. Male fertility rates are markedly different from female fertility rates in developing countries, and documenting both male and female fertility provides a more complete picture of fertility.

  1. Mortality-fertility synergies during the demographic transition in the developed world. (United States)

    Sánchez-Barricarte, Jesús J


    The classic theory used to explain the demographic transition assumes that mortality is the key explanatory variable influencing the decline in fertility. However, the empirical results obtained in what is known as the Princeton European Fertility Project have led many specialists to question this assumption. Using both national and provincial aggregated data for 25 countries over a long time span, the analysis reported in this paper found that mortality does indeed play a fundamental role in accounting for the main demographic changes that occurred both before and during the transitional period. Others' research based on individual data has shown clearly that the number of surviving children was indeed an important factor for reproductive decisions. My analysis, using aggregated data, reached largely similar conclusions regarding the role of mortality in changing reproductive trends, via its impact on nuptiality and marital fertility at different stages of the demographic transition.

  2. Rural development--national improvement. (United States)

    Malhotra, R C


    Rural development should be viewed as the core of any viable strategy for national development in developing countries where an average 2/3 of the population live in rural areas. Rural development is multisectoral, including economic, sociopolitical, environmental, and cultural aspects of rural life. Initially, the focus is on the provision of basic minimum needs in food, shelter, clothing, health, and education, through optimum use and employment of all available resources, including human labor. The development goal is the total development of the human potential. The hierarchy of goals of development may be shown in the form of an inverted pyramid. At the base are basic minimum needs for subsistence whose fulfillment leads to a higher set of sociopolitical needs and ultimately to the goal of total developmentand the release of creative energies of every individual. If development, as outlined, were to benefit the majority of the people then they would have to participate in decision making which affects their lives. This would require that the people mobilize themselves in the people'ssector. The majority can equitably benefit from development only if they are mobilized effectively. Such mobilization requires raising the consciousness of the people concerning their rights and obligations. All development with the twin objectives of growth with equity could be reduced to restructuring the socioeconomic, and hence political relationships. Desinging and implementing an intergrated approach to rural development is the 1st and fundamental issue of rural development management. The commonly accepted goals and objectives of a target group oriented antipoverty development strategy include: higher productivity and growth in gross national product (GNP); equitable distribution of the benefits of development; provision of basic minimum needs for all; gainful employment; participation in development; self reliance or self sustaining growth and development; maintenance of

  3. Essential role of maternal UCHL1 and UCHL3 in fertilization and preimplantation embryo development (United States)

    Mtango, Namdori R.; Sutovsky, Miriam; Susor, Andrej; Zhong, Zhisheng; Latham, Keith E.; Sutovsky, Peter


    Posttranslational protein modification by ubiquitination, a signal for lysosomal or proteasomal proteolysis, can be regulated and reversed by deubiquitinating enzymes (DUBs). This study examined the roles of UCHL1 and UCHL3, two members of ubiquitin C-terminal hydrolase (UCH) family of DUBs, in murine fertilization and preimplantation development. Before fertilization, these proteins were associated with the oocyte cortex (UCHL1) and meiotic spindle (UCHL3). Intracytoplasmic injection of the general UCH-family inhibitor ubiquitin-aldehyde (UBAL) or antibodies against UCHL3 into mature metaphase II oocytes blocked fertilization by reducing sperm penetration of the zona pellucida and incorporation into the ooplasm, suggesting a role for cortical UCHL1 in sperm incorporation. Both UBAL and antibodies against UCHL1 injected at the onset of oocyte maturation (germinal vesicle stage) reduced the fertilizing ability of oocytes. The subfertile Uchl1gad−/− mutant mice showed an intriguing pattern of switched UCH localization, with UCHL3 replacing UCHL1 in the oocyte cortex. While fertilization defects were not observed, the embryos from homozygous Uchl1gad−/− mutant females failed to undergo morula compaction and did not form blastocysts in vivo, indicating a maternal effect related to UCHL1 deficiency. We conclude that the activity of oocyte UCHs contributes to fertilization and embryogenesis by regulating the physiology of the oocyte and blastomere cortex. PMID:21678411

  4. The fertility quality of life (FertiQoL) tool: development and general psychometric properties. (United States)

    Boivin, Jacky; Takefman, Janet; Braverman, Andrea


    To develop the first international instrument to measure fertility quality of life (FertiQoL) in men and women experiencing fertility problems, to evaluate the preliminary psychometric properties of this new tool and to translate FertiQoL into multiple languages. We conducted a survey, both online and in fertility clinics in USA, Australia/New Zealand, Canada and UK. A total of 1414 people with fertility problems participated. The main outcome measure was the FertiQoL tool. FertiQoL consists of 36 items that assess core (24 items) and treatment-related quality of life (QoL) (10 items) and overall life and physical health (2 items). Cronbach reliability statistics for the Core and Treatment FertiQoL (and subscales) were satisfactory and in the range of 0.72 and 0.92. Sensitivity analyses showed that FertiQoL detected expected relations between QoL and gender, parity and support-seeking. FertiQoL was translated into 20 languages by the same translation team with each translation verified by local bilingual fertility experts. FertiQoL is a reliable measure of the impact of fertility problems and its treatment on QoL. Future research should establish its use in cross-cultural research and clinical work.

  5. Indian Reserves: Canada's Developing Nations


    Musto, Richard J.


    Indian reserves are the most visible reminder of the separation of aboriginal people from the rest of Canada and other Canadians. Illness patterns and social conditions in Native communities closely parallel those in developing nations. While they continue to have a large burden of infectious diseases, these groups also have an increased incidence of chronic and lifestyle diseases as well as environment-related conditions. Similarities can be seen in urban areas between immigrants from abroad...

  6. Cultural policy for national development

    Energy Technology Data Exchange (ETDEWEB)

    Nsekela, A.J.


    Cultural policy decisions to alleviate poverty in the Third World are viewed as a moral obligation on the part of industrialized nations to promote an equitable income and service distribution. A review of colonialism on the part of the First toward the Third World concludes that the export of primary products has failed to bring an equal return of industrialization because of the inflated prices of manufactured goods and processes. Policies aimed at eliminating the lack of opportunity in the Third World must attack the three areas of poverty, unemployment, and inequality (racial and sexual). Economic integration of these nations requires a better linkage between natural resources, technology, knowledge, and human resources. More attention is needed to the use of national resources for the manufacture of products that will be used domestically and also exported to international markets. Basic to economic development is the raising of the educational, health, and income levels of the people. A philosophical program is outlined for developing policies that will promote human development. (DCK)

  7. Growth and development, nicotine concentrations and sources of nicotine-n in flue-cured tobacco plants influenced by basal n fertilization time and n fertilizer (15N)

    International Nuclear Information System (INIS)

    Xie Zhijian; Tu Shuxin; Li Jinping; Xu Rubing; Chen Zhenguo; Cao Shiming; Wang Xuelong


    A field experiment with 15 N isotope tracing micro-plots was carried out to study the effects of basal N fertilizer application time (15 d, 30 d before the transplanting) of flue-cured tobacco (FCT) seedlings and nitrogen fertilization (with N and without N) on growth and development, nicotine concentrations and sources of nicotine N of FCT in Laowan (N 31 degree 27', E 111 degree 14', 1 130 m above sea level), a main tobacco production area of Xiangfan city, Hubei province. The results showed that both dry matter accumulation and nicotine concentrations of different parts of FCT increased with growing of plants. The concentrations of nicotine decreased with the ascending of leaf position before topping period, but just opposite after the removal of apex. The proportion of nicotine N from fertilizer to total nicotine N decreased with growing of FCT plants and the rising of leaf position. Applying N fertilizer significantly increased dry matter accumulation of shoot and the nicotine concentrations of different poisional tobacco leaves by 2.1-2.7 fold and 0.1-0.7 fold respectively. Compared with the basal fertilization time 15 d before transplanting, applying basal fertilizer 30 d before transplanting increased the dry matter accumulation and nicotine concentrations of flue-cured tobacco by 2.2%-8.0% and 6.3%-18.5% respectively. There was no significant effects of basal N fertilization time on the proportion of nicotine-N from fertilizer in organs of FCT plants at mature stage. These results suggested that properly putting forward the basal N fertilization time before transplanting make for decrease of nicotine concentrations and improvement of quality of FCT leaves, so as to improve its industrial utilities. (authors)

  8. Atoms in the developing nations

    International Nuclear Information System (INIS)

    Lopes, J.L.


    The history of political and technological developments of nuclear energy in Brazil is traced and arguments presented for pursuing nuclear energy only in those nations with a democratic form of government. Nuclear physics research in Brazil dates back to the 1940s. Its significance was acknowledged with the creation of the National Research Council in 1951. Cooperation with the U.S. Atomic Energy Commission, which would have included the export of thorium-rich minerals to the U.S. in exchange for information and assistance with nuclear power plants in Brazil, was precluded by the McMahon Act. This led to liaisons with West Germany and France in the 1950s. Events since then are outlined in terms of the impact of Brazil's political and economic crises. A nuclear sales agreement with Germany in 1975 has prompted concern over matters of independence and the threat of proliferation

  9. Impact of maternal nutritional level on progeny ovarian development and fertility in cattle (United States)

    Development of replacement beef heifers on dietary energy levels to achieve 55 vs. 65% of mature body weight at 14 mo of age did not affect their ovarian follicular development or subsequent fertility (Eborn et al., 2013, J. Anim. Sci. 91:4168). Because bovine ovarian gametogenesis and folliculogene...

  10. Forecasting the Effects of Fertility Control on Overabundant Ungulates: White-Tailed Deer in the National Capital Region.

    Directory of Open Access Journals (Sweden)

    Ann M Raiho

    Full Text Available Overabundant populations of ungulates have caused environmental degradation and loss of biological diversity in ecosystems throughout the world. Culling or regulated harvest is often used to control overabundant species. These methods are difficult to implement in national parks, other types of conservation reserves, or in residential areas where public hunting may be forbidden by policy. As a result, fertility control has been recommended as a non-lethal alternative for regulating ungulate populations. We evaluate this alternative using white-tailed deer in national parks in the vicinity of Washington, D.C., USA as a model system. Managers seek to reduce densities of white-tailed deer from the current average (50 deer per km2 to decrease harm to native plant communities caused by deer. We present a Bayesian hierarchical model using 13 years of population estimates from 8 national parks in the National Capital Region Network. We offer a novel way to evaluate management actions relative to goals using short term forecasts. Our approach confirms past analyses that fertility control is incapable of rapidly reducing deer abundance. Fertility control can be combined with culling to maintain a population below carrying capacity with a high probability of success. This gives managers confronted with problematic overabundance a framework for implementing management actions with a realistic assessment of uncertainty.

  11. Forecasting the effects of fertility control on overabundant ungulates: White-tailed deer in the National Capital Region (United States)

    Raiho, Ann M.; Hooten, Mevin B.; Bates, Scott; Hobbs, N. Thompson


    Overabundant populations of ungulates have caused environmental degradation and loss of biological diversity in ecosystems throughout the world. Culling or regulated harvest is often used to control overabundant species. These methods are difficult to implement in national parks, other types of conservation reserves, or in residential areas where public hunting may be forbidden by policy. As a result, fertility control has been recommended as a non-lethal alternative for regulating ungulate populations. We evaluate this alternative using white-tailed deer in national parks in the vicinity of Washington, D.C., USA as a model system. Managers seek to reduce densities of white-tailed deer from the current average (50 deer per km2) to decrease harm to native plant communities caused by deer. We present a Bayesian hierarchical model using 13 years of population estimates from 8 national parks in the National Capital Region Network. We offer a novel way to evaluate management actions relative to goals using short term forecasts. Our approach confirms past analyses that fertility control is incapable of rapidly reducing deer abundance. Fertility control can be combined with culling to maintain a population below carrying capacity with a high probability of success. This gives managers confronted with problematic overabundance a framework for implementing management actions with a realistic assessment of uncertainty.

  12. Forecasting the Effects of Fertility Control on Overabundant Ungulates: White-Tailed Deer in the National Capital Region. (United States)

    Raiho, Ann M; Hooten, Mevin B; Bates, Scott; Hobbs, N Thompson


    Overabundant populations of ungulates have caused environmental degradation and loss of biological diversity in ecosystems throughout the world. Culling or regulated harvest is often used to control overabundant species. These methods are difficult to implement in national parks, other types of conservation reserves, or in residential areas where public hunting may be forbidden by policy. As a result, fertility control has been recommended as a non-lethal alternative for regulating ungulate populations. We evaluate this alternative using white-tailed deer in national parks in the vicinity of Washington, D.C., USA as a model system. Managers seek to reduce densities of white-tailed deer from the current average (50 deer per km2) to decrease harm to native plant communities caused by deer. We present a Bayesian hierarchical model using 13 years of population estimates from 8 national parks in the National Capital Region Network. We offer a novel way to evaluate management actions relative to goals using short term forecasts. Our approach confirms past analyses that fertility control is incapable of rapidly reducing deer abundance. Fertility control can be combined with culling to maintain a population below carrying capacity with a high probability of success. This gives managers confronted with problematic overabundance a framework for implementing management actions with a realistic assessment of uncertainty.


    Directory of Open Access Journals (Sweden)



    Full Text Available Agriculture today is a strategic point of a country's economy, providing food based on population, development of internal and external trade and manufacturing industries by supplying raw materials. For Romania, this branch is a strong point both in terms climatic (temperate, balanced relief, soil quality and at the same time is also a way of national development and convergence of rural areas to their full potential untapped. With strong reforms, well implemented, a specific legislative framework which aims to protecting private property, Romania could reduce the low efficiency and can have a sustainable agriculture. The paper aimed to present the advantages of consuming organic products, and, on the other hand, the advantages of a country in terms of organic farming. European agriculture is a competitive, market-oriented, but also protecting the environment model.

  14. Sperm motility, fertilization, and larval development of silver catfish (Rhamdia quelen in copper-contaminated water

    Directory of Open Access Journals (Sweden)

    Robie Allan Bombardelli


    Full Text Available The objective of this study was to evaluate the effect of copper-contaminated water on sperm motility, fertilization, and embryonic and larval development of silver catfish (Rhamdia quelen. A randomized experimental design with five treatments and four replicates was used. Two experiments were carried out: (1 controlled fertilization was performed under different levels of copper contamination and egg hatching was performed in clean water; and (2 copper-contaminated water was used for both fertilization and hatching assays. The time of sperm motility and sperm motility rates linearly decreased with increasing copper concentration in the water. Fertilization and hatching rates were also affected when the concentrations of copper in the water were above 0.0979 mg Cu+2 L-1 and 0.0331 mg Cu+2 L-1, respectively. Gamete exposure to levels between 15 mg Cu+2 L-1 and 60 mg Cu+2 L-1 for short periods of time negatively affected sperm motility, oocyte fertilization, and egg hatching rates. In addition, when gametes and embryos were exposed at levels above 0.03 mg Cu+2 L-1 during long periods of time, egg hatching rates were reduced, and at levels between 0.05 mg Cu+2 L-1 and 0.20 mg Cu+2 L-1 the number of abnormal larvae increased.

  15. Fertility Preservation Services for Women With Newly Diagnosed Cancer: A National Assessment. (United States)

    Winkelman, William D; Rosen, Mitchell P; Mok-Lin, Evelyn


    To study the resources available for cancer patients once referred for fertility preservation. Cross-sectional study clinics that are members of the Society for Assisted Reproductive Technology assess support for fertility preservation. Surveys were distributed to a total of 1135 members at 394 Society for Assisted Reproductive Technology clinics. Responses were received from 99 individuals representing a total of 84 unique clinics (21.3%). Most clinics (76%) are able to see new cancer patients within 24 to 48 hours after a referral. Clinics most commonly offer oocyte freezing and embryo freezing (96% and 98%, respectively), with a significantly smaller portion of clinics offering ovarian tissue freezing (26%). Although most clinics offer fertility preservation for breast cancer, hematologic cancers and ovarian cancer, only 31% of clinics offer fertility preservation for pediatric premenarchal cancers. Clinics that receive >20 referrals from oncology centers annually are more likely to be in the Northeast and have an academic affiliation. These clinics are more likely to provide support for patients during their cancer treatment, more likely to have long-term follow-up with cancer patients and similarly more likely to have cancer patients return to take advantage of their treatment. There are significant geographic and clinic variations in support for fertility preservation. Clinics overall are able to expeditiously see patients to avoid delays in oncologic treatment. Clinics that provide additional support and long-term care tend to have a larger oncologic volume and have more patients who utilize their fertility treatment upon completion of cancer therapy.

  16. Organic fertilizer and its effects on the growth and development of tomato crop (Solanum lycopersicum L.

    Directory of Open Access Journals (Sweden)

    Ricardo Augusto Luna Murillo


    Full Text Available Organic fertilizers are one of the alternatives in the group of products used in sustainable agri-culture, mainly what is obtained from organic sources of recyclable nature as compost and vermicompost. The aim of this study was to determine the effect of organic fertilizers on the growth and development of tomato plants. The treatments were vermicompost, water hyacinth, and the combination 50 % vermicompost and 50 % water hyacinth control, using a completely randomized design with five replicates. The work was conducted at the Experimental Center La Playita, belonging to the Technical University of Cotopaxi La Maná extension and plant height, number of fruits, fruit diameter, fruit weight was measured. The results showed that the use of organic fertilizers in tomato plant height stimulated with 114.64 cm, number of fruits with 4.08 fruits, fruit diameter with 7.96 mm and weight of 226.50 g fruits, tomato plants

  17. Developing a Coffee Yield Prediction and Integrated Soil Fertility Management Recommendation Model for Northern Tanzania

    NARCIS (Netherlands)

    Maro, G.P.; Mrema, J.P.; Msanya, B.M.; Janssen, B.H.; Teri, J.M.


    The aim of this study was to develop a simple and quantitative system for coffee yield estimation and nutrient input advice, so as to address the problem of declining annual coffee production in Tanzania (particularly in its Northern coffee zone), which is related to declining soil fertility. The

  18. Student Developed Knowledge Portfolios from a Soil Fertility Course (United States)

    Sindelar, Meghan; Mamo, Martha; Wingeyer, Ana


    Students who have completed the Soil Nutrient Relationships course at the University of Nebraska-Lincoln often contact instructors once they have begun full-time work, seeking reminders of specific concepts. These students either did not take or keep detailed notes during the course. To assist students, instructors have developed a portfolio…

  19. Note on artificial fertilization and early development of Synodontis ...

    African Journals Online (AJOL)

    Eggs obtained from β wild gravid spotted squeaker (Synodontis nigromaculatus Boulenger, 1905) were (entitled and incubated in plastic containers. Eggs are non-sticky, negatively buoyant and hatchafier 35 h at water temperatures between 24 and 27°C. Development up to 226 h is described.

  20. Spatial Variation of Sub-national Fertility Trends in Austria, Germany and Switzerland

    Directory of Open Access Journals (Sweden)

    Stuart Basten


    Based on the results of this analysis, we conclude that the recent degree of fertility convergence between regions within countries – particularly at the macro-regional level – is, indeed, striking. However, taking a long-term perspective, we are able to identify some substantial time periods over the last 150 years in which regional fertility levels diverged. This implies that the current picture must not necessarily constitute Fukuyama’s “end of history” over the coming decades. Moreover, the study of local-level data reveals that, in contrast to the overall macro-regional fertility convergence process in all three countries, a trend towards divergence can be observed within the city of Bremen. This demonstrates that local divergence can run parallel to overall regional convergence.

  1. Development and evaluation of a decision aid about fertility preservation for Dutch breast cancer patients : informing patients about fertility preservation

    NARCIS (Netherlands)

    Garvelink, Mirjam Marjolein


    In the Netherlands, information provision about fertility preservation (FP) for young women with breast cancer is not sufficient. Since an increasing number of Dutch breast cancer patients will face this preference-sensitive decision each year, there is a clear need for improvement of information

  2. Sildenafil citrate (Viagra) impairs fertilization and early embryo development in mice. (United States)

    Glenn, David R J; McClure, Neil; Cosby, S Louise; Stevenson, Michael; Lewis, Sheena E M


    To determine the effects of sildenafil citrate, a cyclic monophosphate-specific type 5 phosphodiesterase inhibitor known to affect sperm function, on fertilization and early embryo cleavage. This acute mammal study included male and female mice assigned randomly, the females sacrificed after mating and their oocytes/embryos evaluated at four time periods after treatment. Academic research environment. Male and female CBAB(6) mice. Female mice were injected intraperitoneally with 5 IU gonadotropin (hCG) to stimulate follicular growth and induce ovulation. They were each caged with a male that had been gavaged with sildenafil citrate (0.06 mg/0.05 mL) and allowed to mate. After 12, 36, 60, and 84 h, females were killed, their oviducts were dissected out, and retrieved embryos were assessed for blastomere number and quality. Fertilization rates and numbers of embryos were evaluated after treatment. Fertilization rates (day 1) were markedly reduced (-33%) in matings where the male had taken sildenafil citrate. Over days 2-4, the numbers of embryos developing in the treated group were significantly fewer than in the control group. There was also a trend for impaired cleavage rates within those embryos, although this did not reach significance. The impairments to fertility caused by sildenafil citrate have important implications for infertility centers and for couples who are using this drug precoitally while attempting to conceive.

  3. Effects of Simulated Mobile Phone Electromagnetic Radiation on Fertilization and Embryo Development. (United States)

    Chen, Hong; Qu, Zaiqing; Liu, Wenhui


    This study investigated the effects of 935-MHz electromagnetic radiation (ER) on fertilization and subsequent embryonic development in mice. Ovulating mice were irradiated at three ER intensities for 4 h/day (d) or 2 h/d for three consecutive days; the ova were then harvested for in vitro fertilization to observe the 6-h fertilization rate (6-FR), 72-h morula rate (72-MR), and 110-h blastula rate (110-BR). Compared with the control group, the 6-FR, 72-MR, and 110-BR were decreased in the low ER intensity group, but the differences were not significant; in the mid- and high-intensity ER groups, 72-MR and 110-BR in the 4 h/d and 2 h/d subgroups were decreased, showing significant differences compared with the control group. Moreover, the comparison between 4 h/d and 2 h/d subgroups showed significant differences. Mid- and high-intensity ER at 935 MHz can reduce the fertilization rate in mice, and reduce the blastulation rate, thus reducing the possibility of embryo implantation.

  4. Fertility Differentials among Religious Minorities : Cross-national and Regional Evidence from India and Bangladesh

    NARCIS (Netherlands)

    Sahu, Biswamitra; van Wissen, L. J. G.; Hutter, Inge; Bosch, Alinda


    The article examines the independent effect of religious minority status on fertility at two levels i.e. cross-country level of India and Bangladesh and intra-country level (district) of India. Demographic and health survey data from India (20052006) and Bangladesh (20062007) are used for the

  5. Fertility differentials among religious minorities: cross-national and regional evidence from India and Bangladesh

    NARCIS (Netherlands)

    Sahu, B.; van Wissen, L.J.G.; Hutter, I.; Bosch, A.


    The article examines the independent effect of religious minority status on fertility at two levels i.e. cross-country level of India and Bangladesh and intra-country level (district) of India. Demographic and health survey data from India (2005–2006) and Bangladesh (2006–2007) are used for the

  6. Soils, Crops and Fertilizer Use. A What, How and Why Guide. Appropriate Technologies for Development. Reprint R-8. (United States)

    Leonard, David

    This manual, prepared for use by Peace Corps volunteers in developing countries, has been designed as an on-the-job reference for soil management and fertilizer use at the small farmer level. It provides information on yield-boosting techniques, especially in the areas of soil conservation, organic and chemical fertilizer use, and the safe and…

  7. The Pathways fertility preservation decision aid website for women with cancer: development and field testing. (United States)

    Woodard, Terri L; Hoffman, Aubri S; Covarrubias, Laura A; Holman, Deborah; Schover, Leslie; Bradford, Andrea; Hoffman, Derek B; Mathur, Aakrati; Thomas, Jerah; Volk, Robert J


    To improve survivors' awareness and knowledge of fertility preservation counseling and treatment options, this study engaged survivors and providers to design, develop, and field-test Pathways: a fertility preservation patient decision aid website for young women with cancer©. Using an adapted user-centered design process, our stakeholder advisory group and research team designed and optimized the Pathways patient decision aid website through four iterative cycles of review and revision with clinicians (n = 21) and survivors (n = 14). Field-testing (n = 20 survivors) assessed post-decision aid scores on the Fertility Preservation Knowledge Scale, feasibility of assessing women's decision-making values while using the website, and website usability/acceptability ratings. Iterative stakeholder engagement optimized the Pathways decision aid website to meet survivors' and providers' needs, including providing patient-friendly information and novel features such as interactive value clarification exercises, testimonials that model shared decision making, financial/referral resources, and a printable personal summary. Survivors scored an average of 8.2 out of 13 (SD 1.6) on the Fertility Preservation Knowledge Scale. They rated genetic screening and having a biological child as strong factors in their decision-making, and 71% indicated a preference for egg freezing. Most women (> 85%) rated Pathways favorably, and all women (100%) said they would recommend it to other women. The Pathways decision aid is a usable and acceptable tool to help women learn about fertility preservation. The Pathways decision aid may help women make well-informed values-based decisions and prevent future infertility-related distress.

  8. Fertility outcome and information on fertility issues in individuals with different forms of disorders of sex development: findings from the dsd-LIFE study. (United States)

    Słowikowska-Hilczer, Jolanta; Hirschberg, Angelica Lindén; Claahsen-van der Grinten, Hedi; Reisch, Nicole; Bouvattier, Claire; Thyen, Ute; Cohen Kettenis, Peggy; Roehle, Robert; Köhler, Birgit; Nordenström, Anna


    To investigate fertility outcome in individuals with different forms of disorders of sex development (DSD), if assisted reproductive technology (ART) was used, and the patients' satisfaction with the information they had received. A cross-sectional multicenter study, dsd-LIFE. Not applicable. A total of 1,040 patients aged ≥16 years with different DSD diagnoses participated. A web-based questionnaire was filled out by all participants. The participants could chose to take part in somatic investigations including ultrasonography. Information on partner, number of children, ART, adoption and step-children, general health, presence of gonads and uterus, current education and economic situation, received information on fertility issues, and satisfaction with the information, was collected. In the total cohort, mean age 32 years, 33% lived with a partner, but only 14% reported having at least one child including 7% with ART, 4% adopted. Only 3.5% of the total cohort had been able to reproduce without ART, most frequently women with congenital adrenal hyperplasia, and only 0.7% of participants with other diagnoses. Of the participants, 72% had received information on fertility, but 17% were not satisfied with the information. Fertility outcome is significantly reduced in all types of DSD; however, fertility potential should be assessed individually. The satisfaction with how fertility problems have been discussed can be improved. The care of patients with DSD is complex, should be individualized, and new treatment possibilities incorporated. A close collaboration in multidisciplinary teams is therefore essential to improve the situation for individuals with DSD. Copyright © 2017 American Society for Reproductive Medicine. Published by Elsevier Inc. All rights reserved.

  9. The intergenerational transmission of divorce in cross-national perspective: results from the Fertility and Family Surveys. (United States)

    Dronkers, Jaap; Harkonen, Juho


    We used data on women's first marriages from the Fertility and Family Surveys to analyse the intergenerational transmission of divorce across 18 countries and to seek explanations in macro-level characteristics for the cross-national variation. Our results show that women whose parents divorced have a significantly higher risk of divorce in 17 countries. There is some cross-national variation. When compared with the USA, the association is stronger in six countries. This variation is negatively associated with the proportion of women in each cohort who experienced the divorce of their parents and with the national level of women's participation in the labour force during childhood. We conclude that differences in the contexts in which children of divorce learn marital and interpersonal behaviour affect the strength of the intergenerational transmission of divorce.

  10. Fertility treatment: long-term growth and mental development of the children. (United States)

    Bay, Bjørn


    Fertility treatment has been associated with obstetrical and perinatal complications. It is, however, uncertain whether fertility treatment or parental subfertility is associated with long-term development of the children. We aimed to assess the growth and mental health of children and adolescents conceived after fertility treatment compared to spontaneously conceived controls. First, we evaluated all previous studies comparing neurodevelopmental outcomes between children conceived after fertility treatment and spontaneous conceived controls. The systematic review clarified methodological limitations in the existing literature on the long-term development of children conceived after medical assisted reproduction. Although several studies had been published, large, well-controlled studies with long-term follow-up and thorough statistical adjustments were still few. Second, we evaluated the children's mental health by assessing the risk of mental disorders. We studied a population of 555,828 children conceived after spontaneous conception and 33,139 children conceived after fertility treatment with follow-up in 2012 when the children were 8-17 years old. The absolute risk and hazard ratio of overall and specific mental disorders were estimated while adjusting for potential confounding variables. Further, we estimated the association between subtypes of procedures, hormonal treatment, gamete types and cause of infertility on the one hand and the risk of mental disorders on the other. Children conceived after ovulation induction had a low, but significantly increased risks of autism spectrum disorders, hyperkinetic disorders, conduct, emotional, or social disorders, and tic disorders. Children conceived after IVF or ICSI showed no increased risk, except for a small risk of tic disorders. There was no risk systematically related to any specific type of hormone drug treatment. Thus, the increased risks may rely on residual confounding such as unknown parental factors

  11. Developing nations: four environmental profiles. (United States)

    Brown, J W


    Mexico and the US share a long border as well as strong cultural and economic ties. Mexico bought $25 billion worth of American goods in 1989. 1 million workers enter the labor market in Mexico every year. Mexico City is heavily polluted, 40% of the rural population is malnourished, and deforestation and desertification further damage the environment. Mexican real wages dropped 25% in the 1980s as oil prices declined. Egypt's arable land area is only 4% of the total, water supplies are scarce, but its human resources are abundant. 3 million Egyptians work overseas. The runaway population growth means that at the current rate it will double by 2012 from 50 million in 1990 threatening the stability of the country. Food production is off because of salinization caused by the Aswan Dam. Kenya has weathered droughts in the 1980s without major upheavals, but the softening of world coffee and tea prices, fears of European tourists, and more expensive imported oil have weakened the economy. The population doubled from 8 million in 1960 to 16 million in 1980 with a fertility rate of 8 children/woman. The prospect is 40 million by 2000 and 80 million by 2020. Deforestation caused by fuelwood needs has increased erosion resulting in reduced agricultural productivity. Agroforestry training and more energy efficiency are required, and water supplies are also insufficient. The Philippines uplands have experienced environmental degradation caused by population pressure: increase from 19 million in 1948 to 63 million in 1988. Since ownership of good cropland is concentrated in a few wealthy families landless people clear forests for cultivation leading to erosion. Logging also contributes to deforestation, but environmental destruction is not among government priorities.


    African Journals Online (AJOL)

    within the interest and capabilities of all humans regardless of race, gender, national- ity or ethnicity (Byant & Swinton, ... and technology among men and women that are taken for granted have changed. The marginalization of .... Secondly, science and technology are perceived as powerful model for understanding and ...

  13. When Do Laws Matter? National Minimum-Age-of-Marriage Laws, Child Rights, and Adolescent Fertility, 1989–2007 (United States)

    Kim, Minzee; Longhofer, Wesley; Boyle, Elizabeth Heger; Nyseth, Hollie


    Using the case of adolescent fertility, we ask the questions of whether and when national laws have an effect on outcomes above and beyond the effects of international law and global organizing. To answer these questions, we utilize a fixed-effect time-series regression model to analyze the impact of minimum-age-of-marriage laws in 115 poor- and middle-income countries from 1989 to 2007. We find that countries with strict laws setting the minimum age of marriage at 18 experienced the most dramatic decline in rates of adolescent fertility. Trends in countries that set this age at 18 but allowed exceptions (for example, marriage with parental consent) were indistinguishable from countries that had no such minimum-age-of-marriage law. Thus, policies that adhere strictly to global norms are more likely to elicit desired outcomes. The article concludes with a discussion of what national law means in a diffuse global system where multiple actors and institutions make the independent effect of law difficult to identify. PMID:25525281


    Directory of Open Access Journals (Sweden)

    I. A. Korneev


    Full Text Available Testosterone replacement therapy (TRT allows to combat the symptoms of age-related androgen deficiency (AAD; however, it may have side effects, including the reduction in sperm count and even complete cessation of spermatogenesis and development of azoospermia. The fertility may not be restored even within 18 month after treatment completion. Russian researcher explored the impact of TRT with gel on the ejaculate parameters in men with hypogonadism and observed no negative effects on spermatogenesis within 3 months after treatment initiation. We describe a clinical case of reversible azoospermia induced by a relatively short course of TRT with gel. Fertilizing capacity of sperm was finally restored, which was confirmed by a clinical pregnancy obtained by in vitro fertilization. Physicians prescribing TRT should inform their patients that such treatment is contraindicated to those men who would like to preserve their fertility and explain that the restoration of fertility will take some time after treatment completion.

  15. Insecurity and national economic development implications for ...

    African Journals Online (AJOL)

    Insecurity and national economic development implications for Nigeria's vision 20: 2020. ... International Journal of Development and Management Review ... These social menace trigger off a worrisome sense of insecurity that challenge Nigeria's efforts towards national economic development and consequently its vision ...

  16. Development of a biologically based fertilizer, incorporating Bacillus megaterium A6, for improved phosphorus nutrition of oilseed rape. (United States)

    Hu, Xiaojia; Roberts, Daniel P; Xie, Lihua; Maul, Jude E; Yu, Changbing; Li, Yinshui; Zhang, Shujie; Liao, Xing


    Sustainable methods with diminished impact on the environment need to be developed for the production of oilseed rape in China and other regions of the world. A biological fertilizer consisting of Bacillus megaterium A6 cultured on oilseed rape meal improved oilseed rape seed yield (P rape meal without strain A6 in 1 of 2 experiments, suggesting a role for strain A6 in improving yield. Strain A6 was capable of solubilizing phosphorus from rock phosphate in liquid culture and produced enzymes capable of mineralizing organic phosphorus (acid phosphatase, phytase) in liquid culture and in the biological fertilizer. The biologically based fertilizer, containing strain A6, improved plant phosphorus nutrition in greenhouse pot experiments resulting in significantly greater available phosphorus in natural soil and in significantly greater plant phosphorus content relative to the nontreated control. Seed yield and available phosphorus in natural soil were significantly greater with a synthetic chemical fertilizer treatment, reduced in phosphorus content, than the biological fertilizer treatment, but a treatment containing the biological fertilizer combined with the synthetic fertilizer provided the significantly greatest seed yield, available phosphorus in natural soil, and plant phosphorus content. These results suggest that the biological fertilizer was capable of improving oilseed rape seed yield, at least in part, through the phosphorus-solubilizing activity of B. megaterium A6.

  17. Sperm incorporation and pronuclear development during fertilization in the freshwater bivalve Dreissena polymorpha. (United States)

    Misamore, Michael J; Stein, Katheryn K; Lynn, John W


    The invasive zebra mussel, Dreissena polymorpha (D. polymorpha), is proving to be a valuable model for understanding general mechanisms of fertilization, particularly regarding sperm incorporation. In the present study, we tracked the various components of the fertilizing sperm of D. polymorpha during sperm incorporation. During fertilization the sperm membrane remains associated with the egg surface as a distinct patch that disperses over time. This patch marked the site of sperm entry that occurs predominately on the CD blastomere. Taking advantage of the relatively unpigmented cytoplasm, real-time observations were made of the incorporated sperm nucleus as it decondensed and reformed as a developing pronucleus. Pronuclear enlargement occurred progressively and at rates comparable with previously reported fixed-time point observations. Sperm mitochondria were incorporated and separated from the sperm along the leading edge of the decondensing nucleus. Sperm mitochondria labeled with Mitotracker Green remained predominately associated with the CD blastomere following first cleavage and could be tracked to the 16-cell stage before the fluorescence was too faint to detect. Additionally, the demembranated sperm axoneme was incorporated, separated during nuclear decondensation, and remained visible in the egg cytoplasm up to 30 min postinsemination (PI). The present study provides one of the most complete descriptions of incorporation on multiple sperm components into the egg and coordinates fixed-time point observations with real-time observations of sperm within the remarkably transparent egg cytoplasm of zebra mussels.

  18. Study of Sperm Parameters and Sperm Fertility in Mice were Exposed to Tamoxifen during Embryonic Development

    Directory of Open Access Journals (Sweden)

    J Soleimanirad


    Full Text Available Introduction: Tamoxifen is steroidal drug, which mainly treats breast cancer and also used to stimulate ovulation. The purpose of the present study was the evaluation of sperm parameters and fertility of mice whose mothers had received tamoxifen during pregnancy. Methods: In this study, 30 female and 15 male mice of NMRI were selected for mating. After mating female mice were randomly divided into two groups, the first group (control and second group (experimental. All of which contained 15 mice. From the day 13th day of pregnancy, experimental group has received tamoxifen with the dosage of 5 mg/kg for 7 days. After childbirth of the mated mice, male infants were selected. After reaching the age of puberty (6-8Weeks, adult mice were sacrificed by the cervical dislocation. After take sperm, sperm parameters (count, normality and motility, and sperm fertility was performed. In this study SPSS software and statistical t-test was used (p <0.001. Results: Studies showed that sperm parameters and sperm fertilization were significantly different. The number of sperm in the control group was 83.50±28.20 million, and in the experimental group was 60±14.14 million. There was a decrease in average sperm count in the experimental group compared with the control group (p <0.001. Our findings from in vitro fertilization culture media showed that embryos formation and oocyte disruption between control and experimental groups significantly different (p <0.001. Conclusion: The results showed that tamoxifen exposure during development can cause histological changes in the seminiferous tubules, which can lead to infertility.

  19. Microgravity effects during fertilization, cell division, development, and calcium metabolism in sea urchins (United States)

    Schatten, Heide


    The overall objectives of this project are to explore the role of microgravity during fertilization, early development, cytoskeletal organization, and skeletal calcium deposition in a model development system: the sea urchin eggs and embryos. While pursuing these objectives, we have also helped to develop, test, and fly the Aquatic Research Facility (ARF) system. Cells were fixed at preselected time points to preserve the structures and organelles of interest with regards to cell biology events during development. The protocols used for the analysis of the results had been developed during the earlier part of this research and were applied for post-flight analysis using light and (immuno)fluorescence microscopy, scanning electron microscopy, and transmission electron microscopy. The structures of interest are: microtubules during fertilization, cell division, and cilia movement; microfilaments during cell surface restructuring and cell division; centrosomes and centrioles during cell division, cell differentiation, and cilia formation and movement; membranes, Golgi, endoplasmic reticulum, mitochondria, and chromosomes at all stages of development; and calcium deposits during spicule formation in late-stage embryos. In addition to further explore aspects important or living in space, several aspects of this research are also aimed at understanding diseases that affect humans on Earth which may be accelerated in space.

  20. The Maestro (Mro gene is dispensable for normal sexual development and fertility in mice.

    Directory of Open Access Journals (Sweden)

    Lee Smith

    Full Text Available The mammalian gonad arises as a bipotential primordium from which a testis or ovary develops depending on the chromosomal sex of the individual. We have previously used DNA microarrays to screen for novel genes controlling the developmental fate of the indifferent embryonic mouse gonad. Maestro (Mro, which encodes a HEAT-repeat protein, was originally identified as a gene exhibiting sexually dimorphic expression during mouse gonad development. Wholemount in situ hybridisation analysis revealed Mro to be expressed in the embryonic male gonad from approximately 11.5 days post coitum, prior to overt sexual differentiation. No significant expression was detected in female gonads at the same developmental stage. In order to address its physiological function, we have generated mice lacking Maestro using gene targeting. Male and female mice homozygous for a Mro null allele are viable and fertile. We examined gonad development in homozygous male embryos in detail and observed no differences when compared to wild-type controls. Immunohistochemical analysis of homozygous mutant testes of adult mice revealed no overt abnormalities. Expression profiling using DNA microarrays also indicated no significant differences between homozygote embryonic male gonads and controls. We conclude that Maestro is dispensable for normal male sexual development and fertility in laboratory mice; however, the Mro locus itself does have utility as a site for insertion of transgenes for future studies in the fields of sexual development and Sertoli cell function.

  1. On the pace of fertility decline in sub-Saharan Africa


    David Shapiro; Andrew Hinde


    Background: This descriptive finding examines the comparative pace of fertility decline in sub-Saharan Africa, relative to Asia, Latin America and the Caribbean, and Northern Africa.Objective: We seek to determine if fertility decline has been slower in sub-Saharan Africa than elsewhere in the developing world.Methods: United Nations 2017 estimates of national fertility are used in assessing the comparative pace of fertility decline, and the four regions are compared in terms of how far they ...

  2. Nuclear methods in national development

    International Nuclear Information System (INIS)


    This volume of the proceedings of the First National Conference on Nuclear Methods held at Kongo Conference Hotel Zaria from 2-4 September 1993, contains the full text of about 30 technical papers and speeches of invited dignitaries presented at the conference. The technical papers are original or review articles containing results and experiences in nuclear and related analytical techniques. Topics treated include neutron generator operation and control, nuclear data, application of nuclear techniques in environment, geochemistry, medicine, biology, agriculture, material science and industries. General topics in nuclear laboratory organization and research experiences were also covered. The papers were fully discussed during the conference and authors were requested to make changes in the manuscripts where necessary. However, they were further edited. The organizing committee wishes to thank all authors for their presentation and cooperation in submitting their manuscripts promptly and the participants for their excellent contribution during the conference

  3. The United Nations University and Information Development. (United States)

    Tanaskovic, Ines Wesley


    Describes the role of the United Nations University (UNU) in promoting the effective use of new information technologies in support of science and technology for development. The UNU Information and Decision Systems (INDES) project examines the constraints preventing developing nations from using advances in informatics and from integrating their…

  4. Participatory teaching and happiness in developed nations

    NARCIS (Netherlands)

    G.R. Brulé (Gaël); R. Veenhoven (Ruut)


    textabstractAverage happiness differs considerably across nations. Much of this difference is in societal development, but average happiness differs also among developed nations. Much of that latter difference seems to be due to cultural factors and education is a main carrier of these. In that

  5. Towards a national cybersecurity capability development model

    CSIR Research Space (South Africa)

    Jacobs, Pierre C


    Full Text Available - the incident management cybersecurity capability - is selected to illustrate the application of the national cybersecurity capability development model. This model was developed as part of previous research, and is called the Embryonic Cyberdefence Monitoring...


    African Journals Online (AJOL)

    Health insecurity j. Environmental insecurity k. Relationship insecurity l. Religious insecurity m. Moral insecurity n. Insecurity complex. Economic Development. One cannot .... Ekpo, an economist, opined that despite the healthy growth of ..... facilities like roads, potable pipe borne water and constant power supply that can.

  7. Floral development and morphology of Vochysiaceae. II. The position of the single fertile stamen. (United States)

    Litt, Amy; Stevenson, Dennis W


    A conspicuous feature of Vochysiaceae flowers is their single fertile stamen. In some genera, the stamen is in front of a petal, whereas in others it is in front of a sepal. This difference has been attributed to two independent reductions, which implies the stamen is not homologous across the family. The observation that genera with an antesepalous stamen have only one petal, whereas those with an antepetalous stamen have three or five petals, led us to the hypothesis that in all genera the stamen arises in an antepetalous position, but that it is displaced during development in single-petaled taxa. We examined developing buds of five genera using scanning electron microscopy and serial sectioning and conclude that the stamen in all genera is fundamentally antepetalous. The stamen is not displaced. The petal, however, appears to be displaced in some genera. Further, the position of the fertile stamen in Erisma has been misinterpreted. We discuss the evolution of the androecium in this family in a phylogenetic context and consider the significance of symmetry and of loss vs. suppression in the development of Vochysiaceae flowers.

  8. Nuclear medicine in developing nations

    International Nuclear Information System (INIS)

    Nofal, M.M.


    Agency activities in nuclear medicine are directed towards effectively applying techniques to the diagnosis and management of patients attending nuclear medicine units in about 60 developing countries. A corollary purpose is to use these techniques in investigations related to control of parasitic diseases distinctive to some of these countries. Through such efforts, the aim is to improve health standards through better diagnosis, and to achieve a better understanding of disease processes as well as their prevention and management. Among general trends observed for the region: Clinical nuclear medicine; Radiopharmaceuticals; Monoclonal antibodies; Radioimmunoassay (RIA); Nuclear imaging

  9. Libraries Are Dynamic Tools for National Development

    Directory of Open Access Journals (Sweden)

    Amaoge Dorathy Agbo


    Full Text Available Building an ideal nation requires a holistic approach. All facets of human activity must be harnessed while all indices of nation building must be taken care of. In doing this, all academic and professional disciplines are involved. Libraries are not exception. This paper looks at various types of libraries and their basic functions, their roles in national development, and in particular, the challenges facing library services in Nigeria, such as inadequately trained staff to meet the increasing demands of users.

  10. Foxa2 is essential for mouse endometrial gland development and fertility. (United States)

    Jeong, Jae-Wook; Kwak, Inseok; Lee, Kevin Y; Kim, Tae Hoon; Large, Michael J; Stewart, Colin L; Kaestner, Klaus H; Lydon, John P; DeMayo, Francesco J


    During embryonic development, Foxa2 is required for the formation of the node and notochord, and ablation of this gene results in defects in gastrulation, neural tube patterning, and gut morphogenesis. Foxa2 has been shown to be expressed specifically in the glandular epithelium of the murine uterus. To study the uterine function of Foxa2, this gene was conditionally ablated in the mouse uterus by crossing mice with floxed Foxa2 alleles, Foxa2(loxP/loxP), with the Pgr(cre) mouse model. Pgr(cre/+) Foxa2(loxP/loxP) mice showed significantly reduced fertility. Analysis of the uterus on Day 5.5 of pregnancy showed disrupted blastocyst implantation. Pgr(cre/+) Foxa2(loxP/loxP) mice also showed a severe impairment of the uterus to respond to the artificial induction of the decidual response. Morphological examination of the uteri of these mice showed a severe reduction in the number of endometrial glands. The loss of endometrial glands resulted in the reduction of leukemia inhibitory factor (Lif) expression. The lack of a decidual response could be partially rescued by an intrauterine injection of LIF before the initiation of the decidual response. This analysis demonstrates that Foxa2 regulates endometrial gland development and that mice with a loss of endometrial glands cannot support implantation in part due to the loss of LIF, which is a requisite for fertility in the mouse.

  11. Internalization of silver nanoparticles into mouse spermatozoa results in poor fertilization and compromised embryo development (United States)

    Yoisungnern, Ton; Choi, Yun-Jung; Woong Han, Jae; Kang, Min-Hee; Das, Joydeep; Gurunathan, Sangiliyandi; Kwon, Deug-Nam; Cho, Ssang-Goo; Park, Chankyu; Kyung Chang, Won; Chang, Byung-Soo; Parnpai, Rangsun; Kim, Jin-Hoi


    Silver nanoparticles (AgNPs) have many features that make them attractive as medical devices, especially in therapeutic agents and drug delivery systems. Here we have introduced AgNPs into mouse spermatozoa and then determined the cytotoxic effects of AgNPs on sperm function and subsequent embryo development. Scanning electron microscopy and transmission electron microscopy analyses showed that AgNPs could be internalized into sperm cells. Furthermore, exposure to AgNPs inhibited sperm viability and the acrosome reaction in a dose-dependent manner, whereas sperm mitochondrial copy numbers, morphological abnormalities, and mortality due to reactive oxygen species were significantly increased. Likewise, sperm abnormalities due to AgNPs internalization significantly decreased the rate of oocyte fertilization and blastocyst formation. Blastocysts obtained from AgNPs-treated spermatozoa showed lower expression of trophectoderm-associated and pluripotent marker genes. Overall, we propose that AgNPs internalization into spermatozoa may alter sperm physiology, leading to poor fertilization and embryonic development. Such AgNPs-induced reprotoxicity may be a valuable tool as models for testing the safety and applicability of medical devices using AgNPs. PMID:26054035

  12. Developing a National Geography Curriculum for Australia (United States)

    Maude, Alaric Mervyn


    Australia is in the process of implementing a national geography curriculum to replace the separate state and territory curriculums. The paper describes the process of curriculum development, and identifies the different groups that were involved. These included the board and staff of the national curriculum authority, geography teachers across…

  13. A small population of hypothalamic neurons govern fertility: the critical role of VAX1 in GnRH neuron development and fertility maintenance. (United States)

    Hoffmann, Hanne M; Mellon, Pamela L


    Fertility depends on the correct maturation and function of approximately 800 gonadotropin-releasing hormone (GnRH) neurons in the brain. GnRH neurons are at the apex of the hypothalamic-pituitary-gonadal axis that regulates fertility. In adulthood, GnRH neurons are scattered throughout the anterior hypothalamic area and project to the median eminence, where GnRH is released into the portal vasculature to stimulate release of luteinizing hormone (LH) and follicle-stimulating hormone (FSH) from the pituitary. LH and FSH then regulate gonadal steroidogenesis and gametogenesis. Absence of GnRH neurons or inappropriate GnRH release leads to infertility. Despite the critical role of GnRH neurons in fertility, we still have a limited understanding of the genes responsible for proper GnRH neuron development and function in adulthood. GnRH neurons originate in the olfactory placode then migrate into the brain. Homeodomain transcription factors expressed within GnRH neurons or along their migratory path are candidate genes for inherited infertility. Using a combined in vitro and in vivo approach, we have identified Ventral Anterior Homeobox 1 ( Vax1 ) as a novel homeodomain transcription factor responsible for GnRH neuron maturation and fertility. GnRH neuron counts in Vax1 knock-out embryos revealed Vax1 to be required for the presence of GnRH-expressing cells at embryonic day 17.5 (E17.5), but not at E13.5. To localize the effects of Vax1 on fertility, we generated Vax1 flox mice and crossed them with Gnrh cre mice to specifically delete Vax1 within GnRH neurons. GnRH staining in Vax1 flox/flox :GnRH cre mice show a total absence of GnRH expression in the adult. We performed lineage tracing in Vax1 flox/flox :GnRH cre :RosaLacZ mice which proved GnRH neurons to be alive, but incapable of expressing GnRH. The absence of GnRH leads to delayed puberty, hypogonadism and complete infertility in both sexes. Finally, using the immortalized model GnRH neuron cell lines, GN11 and

  14. Development of organic fertilizers from food market waste and urban gardening by composting in Ecuador. (United States)

    Jara-Samaniego, J; Pérez-Murcia, M D; Bustamante, M A; Paredes, C; Pérez-Espinosa, A; Gavilanes-Terán, I; López, M; Marhuenda-Egea, F C; Brito, H; Moral, R


    Currently, the management of urban waste streams in developing countries is not optimized yet, and in many cases these wastes are disposed untreated in open dumps. This fact causes serious environmental and health problems due to the presence of contaminants and pathogens. Frequently, the use of specific low-cost strategies reduces the total amount of wastes. These strategies are mainly associated to the identification, separate collection and composting of specific organic waste streams, such as vegetable and fruit refuses from food markets and urban gardening activities. Concretely, in the Chimborazo Region (Ecuador), more than 80% of municipal solid waste is dumped into environment due to the lack of an efficient waste management strategy. Therefore, the aim of this study was to develop a demonstration project at field scale in this region to evaluate the feasibility of implanting the composting technology not only for the management of the organic waste fluxes from food market and gardening activities to be scaled-up in other developing regions, but also to obtain an end-product with a commercial value as organic fertilizer. Three co-composting mixtures were prepared using market wastes mixed with pruning of trees and ornamental palms as bulking agents. Two piles were created using different proportions of market waste and prunings of trees and ornamental palms: pile 1 (50:33:17) with a C/N ratio 25; pile 2: (60:30:10) with C/N ratio 24 and pile 3 (75:0:25) with C/N ratio 33), prepared with market waste and prunings of ornamental palm. Throughout the process, the temperature of the mixtures was monitored and organic matter evolution was determined using thermogravimetric and chemical techniques. Additionally, physico-chemical, chemical and agronomic parameters were determined to evaluate compost quality. The results obtained indicated that all the piles showed a suitable development of the composting process, with a significant organic matter decomposition

  15. Development of organic fertilizers from food market waste and urban gardening by composting in Ecuador.

    Directory of Open Access Journals (Sweden)

    J Jara-Samaniego

    Full Text Available Currently, the management of urban waste streams in developing countries is not optimized yet, and in many cases these wastes are disposed untreated in open dumps. This fact causes serious environmental and health problems due to the presence of contaminants and pathogens. Frequently, the use of specific low-cost strategies reduces the total amount of wastes. These strategies are mainly associated to the identification, separate collection and composting of specific organic waste streams, such as vegetable and fruit refuses from food markets and urban gardening activities. Concretely, in the Chimborazo Region (Ecuador, more than 80% of municipal solid waste is dumped into environment due to the lack of an efficient waste management strategy. Therefore, the aim of this study was to develop a demonstration project at field scale in this region to evaluate the feasibility of implanting the composting technology not only for the management of the organic waste fluxes from food market and gardening activities to be scaled-up in other developing regions, but also to obtain an end-product with a commercial value as organic fertilizer. Three co-composting mixtures were prepared using market wastes mixed with pruning of trees and ornamental palms as bulking agents. Two piles were created using different proportions of market waste and prunings of trees and ornamental palms: pile 1 (50:33:17 with a C/N ratio 25; pile 2: (60:30:10 with C/N ratio 24 and pile 3 (75:0:25 with C/N ratio 33, prepared with market waste and prunings of ornamental palm. Throughout the process, the temperature of the mixtures was monitored and organic matter evolution was determined using thermogravimetric and chemical techniques. Additionally, physico-chemical, chemical and agronomic parameters were determined to evaluate compost quality. The results obtained indicated that all the piles showed a suitable development of the composting process, with a significant organic matter

  16. Journal of Research in National Development

    African Journals Online (AJOL)

    The Journal of Research in National Development aims to encourage interdisciplinary research, joint authorships and the recognition of the interface among disciplines. Favorite articles are quantitative, empirical and developmentally biased. It aims to serve all with interest in the development of developing countries, ...

  17. Silicon fertilization and soil water tensions on rice development and yield

    Directory of Open Access Journals (Sweden)

    Jakeline R. de Oliveira


    Full Text Available ABSTRACT The cultivation of upland rice (Oryza sativa in Brazil occurs mainly in the Cerrado, a region with adverse weather conditions. The use of silicon in its cultivation becomes important, since this nutrient provides higher rigidity, lower transpiration and higher resistance to dry spells in rice plants. The objective of the present study was to evaluate the effect of silicon fertilization and soil water tensions on upland rice development and yield in a Cerrado Oxisol. A 5 x 5 fractionated factorial with five soil water tensions (0, 15, 30, 45 and 60 kPa and five silicon doses (0, 120, 240, 480 and 960 mg dm-3 was used, which were distributed in a randomized block design, with four replicates. Plant height, number of tillers, number of panicles, number of grains per panicle, numbers of full and empty grains and percentage of empty grains were evaluated. Silicon fertilization promotes increased tillering in rice plants at the dose of 960 mg dm-3. The numbers of tillers and panicles decreased with the application of silicon up to the doses of 460 and 490 mg dm-3, respectively. The increase in soil water tensions reduced plant height and the number of full grains, and increased the percentage of empty grains of upland rice.

  18. Development master arm of 2-DOF planar parallel manipulator for In-Vitro Fertilization (United States)

    Thamrongaphichartkul, Kitti; Vongbunyong, Supachai; Nuntakarn, Lalana


    Micromanipulator is a mechanical device used for manipulating miniature objects in the order of micron. It is widely used in In-Vitro Fertilization (IVF) in which sperms will be held in a micro-needle and penetrate to an oocyte for fertilization. IVF needs to be performed by high skill embryologists to control the movement of the needle accurately due to the lack of tactile perception of the user. Haptic device is a device that can transmit and simulate position, velocity and force in order to enhance interaction between the user and system. However, commercially available haptic devices have unnecessary degrees of freedom and limited workspace which are inappropriate for IVF process. This paper focuses on development of a haptic device for using in IVF process. It will be used as a master arm for the master-slave system for IVF process in order to enhance the ability of users to control the micromanipulator. As a result, the embryologist is able to carry out the IVF process more effectively with having tactile perception.

  19. Therapeutic navigations: National and transnational quests for fertility among Mozambican women and men

    NARCIS (Netherlands)

    Domingues Figueira de Faria, I.


    This thesis explores Mozambican women and couple’s processes of coping with infertility and their national and transnational therapeutic itineraries in the quest for a child. Based on the idea of therapeutic navigation, this work accounts for the manifold social and individual aspects and strategies

  20. Intrauterine Exposure to Paracetamol and Aniline Impairs Female Reproductive Development by Reducing Follicle Reserves and Fertility

    DEFF Research Database (Denmark)

    Holm, Jacob Bak; Mazaud-Guittot, Severine; Danneskiold-Samsøe, Niels Banhos


    Studies report that fetal exposure to paracetamol/acetaminophen by maternal consumption can interfere with male reproductive development. Moreover, recent biomonitoring data report widespread presence of paracetamol in German and Danish populations, suggesting exposure via secondary...... (nonpharmaceutical) sources, such as metabolic conversion from the ubiquitous industrial compound aniline. In this study, we investigated the extent to which paracetamol and aniline can interfere with female reproductive development. Intrauterine exposure to paracetamol by gavage of pregnant dams resulted...... in shortening of the anogenital distance in adult offspring, suggesting that fetal hormone signaling had been disturbed. Female offspring of paracetamol-exposed mothers had ovaries with diminished follicle reserve and reduced fertility. Fetal gonads of exposed animals had also reduced gonocyte numbers...

  1. Does Embryo Culture Medium Influence the Health and Development of Children Born after In Vitro Fertilization? (United States)

    Bouillon, Céline; Léandri, Roger; Desch, Laurent; Ernst, Alexandra; Bruno, Céline; Cerf, Charline; Chiron, Alexandra; Souchay, Céline; Burguet, Antoine; Jimenez, Clément; Sagot, Paul; Fauque, Patricia


    In animal studies, extensive data revealed the influence of culture medium on embryonic development, foetal growth and the behaviour of offspring. However, this impact has never been investigated in humans. For the first time, we investigated in depth the effects of embryo culture media on health, growth and development of infants conceived by In Vitro Fertilization until the age of 5 years old. This single-centre cohort study was based on an earlier randomized study. During six months, in vitro fertilization attempts (No. 371) were randomized according to two media (Single Step Medium—SSM group) or Global medium (Global group). This randomized study was stopped prematurely as significantly lower pregnancy and implantation rates were observed in the SSM group. Singletons (No. 73) conceived in the randomized study were included (42 for Global and 31 for SSM). The medical data for gestational, neonatal and early childhood periods were extracted from medical records and parental interviews (256 variables recorded). The developmental profiles of the children in eight domains (social, self-help, gross motor, fine motor, expressive language, language comprehension, letter knowledge and number knowledge – 270 items) were compared in relation to the culture medium. The delivery rate was significantly lower in the SSM group than in the Global group (p<0.05). The culture medium had no significant effect on birthweight, risk of malformation (minor and major), growth and the frequency of medical concerns. However, the children of the Global group were less likely than those of the SSM group to show developmental problems (p = 0.002), irrespective of the different domains. In conclusion, our findings showed that the embryo culture medium may have an impact on further development. PMID:27008092

  2. Localization of Determinants of Fertility through Measurement Adaptations in Developing-Country Settings: The Case of Iran Comment on “Analysis of Economic Determinants of Fertility in Iran: A Multilevel Approach”

    Directory of Open Access Journals (Sweden)

    Amir Erfani


    Full Text Available Studies investigating fertility decline in developing countries often adopt measures of determinants of fertility behavior developed based on observations from developed countries, without adapting them to the realities of the study setting. As a result, their findings are usually invalid, anomalous or statistically non-significant. This commentary draws on the research article by Moeeni and colleagues, as an exemplary work which has not adapted measures of two key economic determinants of fertility behavior, namely gender inequality and opportunity costs of childbearing, to the realities of Iran’s economy. Measurement adaptations that can improve the study are discussed.

  3. Development of lucerne (Medicago sativa L.) treated with mineral fertilizer and manure at optimal and water deficit conditions. (United States)

    Vasileva, V; Kostov, O; Vasilev, E


    A study on the effect of different rates of mineral fertilizer and manure on yield parameters of lucerne under optimal and water deficit conditions was carried out. Leached chernozem soil and lucerne cultivar Victoria were used. The soil was treated with ammonium nitrate and fully matured cattle manure. The plants were grown under optimum moisture content of 80% and 40% of field capacity. The water deficit stress decreased top and root biomass by 11-75% and 3-29% at mineral and organic fertilization, respectively. The applied mineral and organic N strongly depressed nodules development. Both mineral fertilizer and organic manure at dose of 210 mg N kg(-1) soil completely inhibited the appearance of nodules. Next to nitrogen, water deficit stress further inhibited the development of nodules. Nitrogen fertilization increased seed productivity in the two experimental moisture conditions. The water deficit stress decreased seed productivity by 18 to 33% as compared to optimum conditions. The plant treatments with manure were much more resistant to water deficit and recovering ability of plants was faster as compared to treatments with mineral fertilizer. The application of manure stimulates development of drought-stress tolerance in lucerne. However, the results obtained can be considered for the soil type and experimental conditions used.

  4. National Ignition Facility frequency converter development

    International Nuclear Information System (INIS)

    Barker, C.E.; Auerbach, J.M.; Adams, C.H.


    A preliminary error budget for the third harmonic converter for the National Ignition Facility (NIF) laser driver has been developed using a root-sum-square-accumulation of error sources. Such a budget sets an upper bound on the allowable magnitude of the various effects that reduce conversion efficiency. Development efforts on crystal mounting technology and crystal quality studies are discussed

  5. Music, Technology and National Development: Rethinking Some ...

    African Journals Online (AJOL)

    There is equally the tacit acceptance of the importance of the role of technology for music in particular and development in general. This paper examines the background assumptions that set in motion the conference theme, to find out what music can genuinely contribute to national development, given the trajectories which ...

  6. Pilot Project - National Development Research Program (Honduras ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    The idea for a National Research and Training Program (PRIDE, in Spanish) emerged from the IDRC-supported project, "100133 Building Learning Systems for Honduran Development." This grant will support a pilot version of PRIDE consisting of two calls for proposals. The first will focus on poverty and development ...

  7. Reading for national development: Catching them young ...

    African Journals Online (AJOL)

    When a reader is caught young by exposing him to reading early enough, he will develop in speech, visual and auditory discrimination. He will gradually develop stimulating reading maturity – a phase that can make him challenge what he reads in print. There is no doubt that when a nation produces avid readers, it makes ...

  8. Assets of Nation (Pyramid of Economic Development)


    Ahmed, Ovais; Mashkoor, Aasim


    The theory of economic development have designed to explore the assets of nations which explain and analyzed the emphasize on Water crisis, deforestation, land of agriculture for yield and minerals. these are the main resources of improving and generating economic health. we analyzed further significant factors which help to designed the qualitative theory of economic development.

  9. Macroeconomic model of national economy development (extended

    Directory of Open Access Journals (Sweden)

    M. Diaconova


    Full Text Available The macroeconomic model offered in this paper describes complex functioning of national economy and can be used for forecasting of possible directions of its development depending on various economic policies. It is the extension of [2] and adaptation of [3]. With the purpose of determination of state policies influence in the field of taxes and exchange rate national economy is considered within the framework of three sectors: government, private and external world.

  10. “Why Nations Fail” to Develop

    Directory of Open Access Journals (Sweden)

    Victor E. Dike


    Full Text Available This article focuses on the forces that prevent nations from developing politically, socially, and economically or why some of them have failed to achieve their purpose. It draws profusely from two inspiring books: Why Nations Fail and Leading From the Emerging Future to explore as to whether or not the political leaders of Nigeria can learn any lesson from the seminal work. The books concentrate on practical approaches that empower political leaders to shift their mind-sets to enable them to transform their extant extractive political and economic institutions that hinder national development. Unlike previous studies on leadership and development in Nigeria, which have observed that the system has been rendered unproductive by poor leadership, this article argues that the problem with Nigeria is that the political leaders have failed to shift their engrained mind-sets from “ego-system awareness to eco-system reality” to enable them to build and maintain effective institutions and infrastructure that drive the economy and develop the nations. It also argues that discussion about the leaders’ mind-set and national development deserves a different approach to transform the nation’s ossified institutions into innovative and creative ones. This will encourage the leaders to collectively shift their mental models to design and implement growth policies that will fit into the 21st-century economy and empower them to lead from the emerging future.

  11. Social and economic growth of developing nations

    International Nuclear Information System (INIS)

    Gregersen, H.M.; Laarman, J.G.


    This paper reports on social and economic growth of developing nations. Trees and forests are often of immeasurable importance to developing countries of the world. To be of value, however, effective and efficient institutions, programs, and policies must be designed and focused on such resources. Forest economics and policy researchers can contribute much to such activities. To be most effective, forest economics research should be designed to improve understanding of social forestry, watershed management, and nontimber forest outputs; enhance ability to effectively address environmental consequences of forestry development; heighten skill in guiding development of industrial forestry enterprises; and improve effectiveness of international aid for forestry development. Guided by such strategic directions, forest economics research can contribute much to the economic and social well-being of developing nations

  12. National Strategies for Public Library Development

    DEFF Research Database (Denmark)

    Kann-Christensen, Nanna


    by The Danish Agency for Libraries and Media, and The Swedish Arts Council, who both administer development grants to public libraries. The paper identifies both differences and similarities in both the means to (the political agendas) and the objectives of governmental influence in the libraries.......The economic rationale of New Public Management (NPM) is used in both Sweden and Denmark in order to employ the national cultural policies in local development projects. The paper discusses two different organizational models that are used in order for the national level to be able to exercise...... policies on the local level are discussed. according to the national goals and cultural policies for libraries. This is done in order to point towards a possible relationship between the political means and ends regarding library development. The two models to be discussed are the systems practiced...

  13. Fertilization effects on biomass production, nutrient leaching and budgets in four stand development stages of short rotation forest poplar

    DEFF Research Database (Denmark)

    Georgiadis, Petros; Nielsen, Anders Tærø; Stupak, Inge


    Abstract Dedicated energy poplar plantations have a high biomass production potential in temperate regions, which may be further increased by improved management practices. The aim of this study was to investigate the effects of fertilization on short rotation forest poplar established on former...... arable land. We examined the effects on biomass production, net nutrient uptake in stems and branches, nutrient leaching fluxes and changes to the nutrient budgets calculated as inputs minus outputs. An experiment was carried out in four stands of different development stages, the establishment (EST...... leaching based on water fluxes modelled with CoupModel and soil solution analyses and calculated the nutrient budgets. Fertilization effects depended on the stage of stand development, but were inconsistent in time. The biomass production increased in EST in the first year after fertilization and in PT...

  14. National strategy for sustainable development: 5. report

    International Nuclear Information System (INIS)


    After an introduction on the assessment and perspectives of the French national strategy for a sustainable development, this report presents actions which are associated with different themes: social dimension of the sustainable development, the citizen as an actor of sustainable development, territories, economic activities, companies and consumers, climate change and energy, transports, agriculture and fishery, prevention of risks, pollutions and other hazards for health and the environment, an exemplary State, research and innovation, international action

  15. Development of a phosphorus index for pastures fertilized with poultry litter--factors affecting phosphorus runoff. (United States)

    DeLaune, Paul B; Moore, Philip A; Carman, Dennis K; Sharpley, Andrew N; Haggard, Brian E; Daniel, Tommy C


    Currently, several state and federal agencies are proposing upper limits on soil test phosphorus (P), above which animal manures cannot be applied, based on the assumption that high P concentrations in runoff are due to high soil test P. Recent studies show that other factors are more indicative of P concentrations in runoff from areas where manure is being applied. The original P index was developed as an alternative P management tool incorporating factors affecting both the source and transport of P. The objective of this research was to evaluate the effects of multiple variables on P concentrations in runoff water and to construct a P source component of a P index for pastures that incorporates these effects. The evaluated variables were: (i) soil test P, (ii) soluble P in poultry litter, (iii) P in poultry diets, (iv) fertilizer type, and (v) poultry litter application rate. Field studies with simulated rainfall showed that P runoff was affected by the amount of soluble P applied in the fertilizer source. Before manure applications, soil test P was directly related to soluble P concentrations in runoff water. However, soil test P had little effect on P runoff after animal manure was applied. Unlike most other P indices, weighting factors of the P source components in the P index for pastures are based on results from runoff studies conducted under various management scenarios. As a result, weighting factors for the P source potential variables are well justified. A modification of the P index using scientific data should strengthen the ability of the P index concept to evaluate locations and management alternatives for P losses.

  16. Contraceptive practices and fertility desires among HIV-infected and uninfected women in Kenya: results from a nationally representative study. (United States)

    Ngugi, Evelyn W; Kim, Andrea A; Nyoka, Raymond; Ng'ang'a, Lucy; Mukui, Irene; Ng'eno, Bernadette; Rutherford, George W


    Prevention of unplanned pregnancies is a critical element in the prevention of mother-to-child transmission of HIV infection, but its potential has not been fully realized. We assessed the utilization of family planning (FP) and fertility desires among women of reproductive age by HIV status. We selected a nationally representative sample of households using a stratified 2-stage cluster design and surveyed women aged 15-49 years. We administered questionnaires and examined predictors of current use of FP and desire for children among sexually active women with known HIV infection and women who were HIV uninfected. Of 3583 respondents, 68.2% were currently using FP, and 57.7% did not desire children in the future. Among women who did not desire children in the future, 70.9% reported that they were using FP, including 68.7% of women with known HIV infection and 71.0% of women who were HIV uninfected. Women with known HIV infection had similar odds of using FP as women with no HIV infection (odds ratio, 1.12; 95% confidence interval: 0.81 to 1.54). Women with no HIV infection had significantly higher adjusted odds of desiring future children (adjusted OR, 2.27; 95% confidence interval: 1.31 to 3.93) than women with known HIV infection. There is unmet need for FP for HIV-infected women, underscoring a gap in the national prevention of mother-to-child transmission of HIV strategy. Efforts to empower HIV-infected women to prevent unintended pregnancies should lead to expanded access to contraceptive methods and take into account women's reproductive intentions.

  17. Contextualising the National Development Plan for enhanced ...

    African Journals Online (AJOL)

    Integrated Development Plans (IDPs) are the planning instruments directed at strategies for enhancing service delivery in local government. As a consequence, capacity initiatives are driven by these plans to address prioritised developmental needs. The key to establishing such initiatives is informed by the National ...

  18. Religion, tolerance and national development: The Nigerian ...

    African Journals Online (AJOL)

    Tolerance as the ability to bear with one another inspite of differences either in opinion, belief or knowledge is an indispensable factor for any meaningful progress and development of any nation. To a keen observer of the daily happenings in Nigeria, religious tolerance is more than a topical issue because of its relevance ...

  19. Cultural vs. Economic: Re-Visiting the Determinants of Fertility at a Sub-National Level in the U.S, 1990 - 2000

    Directory of Open Access Journals (Sweden)

    Jeremy R. Porter


    Full Text Available It is widely accepted that through the past century, and especially since 1950, the world population has grown at an accelerating pace landing the current world's population at about 6.5 billion and, according to UN projections, it is expected to reach 9.1 billion by 2050 (Bongaarts 2005. However, this growth is not uniform and tends to vary both regionally and intra-regionally around the world (Bongaarts 1998. There are competing theories as to the true determinants of fertility levels and these identified patterns (Caldwell 2001. The bulk of these theories pit economic determinants versus socio-cultural determinants as the primary indicators concerning the onset of fertility decline. However, most of this work has had an international focus with very few examining sub-national trends in fertility patterns. This paper draws on the work of one study which examined sub-national trends in the U.S. in hopes of better understanding current trends in determining fertility in the U.S. (Cutright 1983. An OLS regression approach is employed allowing for the examination of the two competing theories. Findings suggest that, while both are certainly significant, the role of economic determinants.

  20. The boron efflux transporter ROTTEN EAR is required for maize inflorescence development and fertility. (United States)

    Chatterjee, Mithu; Tabi, Zara; Galli, Mary; Malcomber, Simon; Buck, Amy; Muszynski, Michael; Gallavotti, Andrea


    Although boron has a relatively low natural abundance, it is an essential plant micronutrient. Boron deficiencies cause major crop losses in several areas of the world, affecting reproduction and yield in diverse plant species. Despite the importance of boron in crop productivity, surprisingly little is known about its effects on developing reproductive organs. We isolated a maize (Zea mays) mutant, called rotten ear (rte), that shows distinct defects in vegetative and reproductive development, eventually causing widespread sterility in its inflorescences, the tassel and the ear. Positional cloning revealed that rte encodes a membrane-localized boron efflux transporter, co-orthologous to the Arabidopsis thaliana BOR1 protein. Depending on the availability of boron in the soil, rte plants show a wide range of phenotypic defects that can be fully rescued by supplementing the soil with exogenous boric acid, indicating that rte is crucial for boron transport into aerial tissues. rte is expressed in cells surrounding the xylem in both vegetative and reproductive tissues and is required for meristem activity and organ development. We show that low boron supply to the inflorescences results in widespread defects in cell and cell wall integrity, highlighting the structural importance of boron in the formation of fully fertile reproductive organs. © 2014 American Society of Plant Biologists. All rights reserved.

  1. Effect of oviduct epithelial cells on the fertilization and development of sheep oocytes in vitro

    DEFF Research Database (Denmark)

    Holm, Peter; Irvine, Brendon J.; Armstrong, David T.


    cells and then transferred to the oviducts of a recipient ewe, 30 h post oestrus, for a 6.5 day period of in vivo culture. Similar rates of fertilization ( 54-58%) and blastocyst development from cleaving zygotes ( 48-69%) were achieved in both experi- ments in vitro with no evident benefit of including...... oviductal cells. In fact, fewer (P= 0 .02) blastocysts developed from cleaved embryos when co-cultured for the 96 h period (Group 4). Whilst the blastocyst development rates obtained in vitro ( 45-58%) were similar to, or higher than (P=0.03 ), those obtained in vivo ( 43%), more than 50% of in vitro cul......- tured embryos in both experiments showed evidence of fragmentation and/or irregular cleavage as well as a lack of firm compaction at the morula stage. Also the blastocysts that had not hatched, or hatched by 7.5 days of in vitro culture had significantly fewer cells than those cultured in vivo (P...

  2. Inspection technologies -Development of national safeguards technology-

    International Nuclear Information System (INIS)

    Hong, J. S.; Kim, B. K.; Kwack, E. H.


    17 facility regulations prepared by nuclear facilities according to the Ministerial Notices were evaluated. Safeguards inspection activities under Safeguards are described. Safeguards inspection equipments and operation manuals to be used for national inspection are also described. Safeguards report are produced and submitted to MOST by using the computerized nuclear material accounting system at state level. National inspection support system are developed to produce the on-site information for domestic inspection. Planning and establishment of policy for nuclear control of nuclear materials, international cooperation for nuclear control, CTBT, strengthening of international safeguards system, and the supply of PWRs to North Korea are also described. (author). 43 tabs., 39 figs


    Directory of Open Access Journals (Sweden)

    Mona Popa


    Full Text Available Our research on the use of slow-release biodegradable fertilizers were applied to Petunia hybrida seedlings of the variety “White Surfinia”. Thus after 10 days subculturing procedure was to apply fertilizers containing NKP24 biodegradable and made in the form of sticks and granules with six concentrations of starch (5%, 10%, 15%, 20%, 25% and 50% quantaties (4-5 grams/ 1 pot. For each pot with of 8 cm diameter, we prepared a mixture of peat and garden soil in a rate of 1:1. During the vegetation periods, morphological analyses were made regarding the development of Petunia hybrida, cv. “White Surfinia”plants: the length of shoots and number of shoot. Average values recorded from morphological determinations after 1 month of starting experiments on biofertilizers influence on growth and development the seedlings of Petunia was demonstrated that the optimal variant was the fertilizer V5 with -25% WF (wood flour to 50% concentration of biofertilizers NKP24 (for both form of sticks A-big and B-medium and for fertilizer form C- granular the V6 variant with -50% concentration of biofertilizers NKP24, the petunia stem was recorded maximum of 58.92 cm length .The research is part of an international project FP7/2008 with the title "Forest Resource Sustainability through Bio-Based-Composite Development" – FORBIOPLAST. Multiple aims of FORBIOPLAST project are the valorization of forest resources for the production of bio-based products.

  4. Growth, development, and fertilizer-15N recovery by the coffee plant

    International Nuclear Information System (INIS)

    Fenilli, Tatiele Anete Bergamo; Reichardt, Klaus; Bacchi, Osny Oliveira Santos; Dourado-Neto, Durval; Favarin, Jose Laercio; Trivelim, Paulo Cesar Ocheuze; Costa, Flavio Murilo Pereira da


    The relationship between growth and fertilizer nitrogen recovery by perennial crops such as coffee is poorly understood and improved understanding of such relations is important for the establishment of rational crop management practices. In order to characterize the growth of a typical coffee crop in Brazil and quantify the recovery of 15 N labeled ammonium sulfate, and improve information for fertilizer management practices this study presents results for two consecutive cropping years, fertilized with 280 and 350 kg ha -1 of N, respectively, applied in four splittings, using five replicates. Shoot dry matter accumulation was evaluated every 60 days, separating plants into branches, leaves and fruits. Labeled sub-plots were used to evaluate N-total and 15 N abundance by mass spectrometry. During the first year the aerial part reached a recovery of 71% of the fertilizer N applied up to February, but this value was reduced to 34% at harvest and 19% at the beginning of the next flowering period due to leaf fall and fruit export. For the second year the aerial part absorbed 36% of the fertilizer N up to March, 47% up to harvest and 19% up to the beginning of the next flowering period. The splitting into four applications of the used fertilizer rates was adequate for the requirements of the crop at these growth stages of the coffee crop. (author)

  5. Gadd45g is essential for primary sex determination, male fertility and testis development.

    Directory of Open Access Journals (Sweden)

    Heiko Johnen

    Full Text Available In humans and most mammals, differentiation of the embryonic gonad into ovaries or testes is controlled by the Y-linked gene SRY. Here we show a role for the Gadd45g protein in this primary sex differentiation. We characterized mice deficient in Gadd45a, Gadd45b and Gadd45g, as well as double-knockout mice for Gadd45ab, Gadd45ag and Gadd45bg, and found a specific role for Gadd45g in male fertility and testis development. Gadd45g-deficient XY mice on a mixed 129/C57BL/6 background showed varying degrees of disorders of sexual development (DSD, ranging from male infertility to an intersex phenotype or complete gonadal dysgenesis (CGD. On a pure C57BL/6 (B6 background, all Gadd45g(-/- XY mice were born as completely sex-reversed XY-females, whereas lack of Gadd45a and/or Gadd45b did not affect primary sex determination or testis development. Gadd45g expression was similar in female and male embryonic gonads, and peaked around the time of sex differentiation at 11.5 days post-coitum (dpc. The molecular cause of the sex reversal was the failure of Gadd45g(-/- XY gonads to achieve the SRY expression threshold necessary for testes differentiation, resulting in ovary and Müllerian duct development. These results identify Gadd45g as a candidate gene for male infertility and 46,XY sex reversal in humans.

  6. Pro-apoptotic Effect of Pifithrin-α on Preimplantation Porcine Fertilized Embryo Development

    Directory of Open Access Journals (Sweden)

    Brendan Mulligan


    Full Text Available The aim of this study was to investigate the impact of a reported p53 inhibitor, pifithrin-α (PFT-α, on preimplantation porcine in vitro fertilized (IVF embryo development in culture. Treatment of PFT-α was administered at both early (0 to 48 hpi, and later stages (48 to 168 hpi of preimplantation development, and its impact upon the expression of five genes related to apoptosis (p53, bak, bcl-xL, p66Shc and caspase3, was assessed in resulting d 7 blastocysts, using real-time quantitative PCR. Total cell numbers, along with the number of apoptotic nuclei, as detected by the in situ cell death detection assay, were also calculated on d 7 in treated and non-treated control embryos. The results indicate that PFT-α, when administered at both early and later stages of porcine IVF embryo development, increases the incidence of apoptosis in resulting blastocysts. When administered at early cleavage stages, PFT-α treatment was shown to reduce the developmental competence of porcine IVF embryos, as well as reducing the quality of resulting blastocysts in terms of overall cell numbers. In contrast, at later stages, PFT-α administration resulted in marginally increased blastocyst development rates amongst treated embryos, but did not affect cell numbers. However, PFT-α treatment induced apoptosis and apoptotic related gene expression, in all treated embryos, irrespective of the timing of treatment. Our results indicate that PFT-α may severely compromise the developmental potential of porcine IVF embryos, and is a potent apoptotic agent when placed into porcine embryo culture media. Thus, caution should be exercised when using PFT-α as a specific inhibitor of p53 mediated apoptosis, in the context of porcine IVF embryo culture systems.

  7. Targets development at Sandia National Laboratories

    International Nuclear Information System (INIS)

    Smith, M.L.; Hebron, D.; Derzon, M.; Olson, R.; Alberts, T.


    For many years, Sandia National Laboratories under contract to the Department of Energy has produced targets designed to understand complex ion beam and z-pinch plasma physics. This poster focuses on the features of target designs that make them suitable for Z-pinch plasma physics applications. Precision diagnostic targets will prove critical in understanding the plasma physics model needed for future ion beam and z-pinch design. Targets are designed to meet specific physics needs; in this case the authors have fabricated targets to maximize information about the end-on versus side-on x-ray emission and z-pinch hohlraum development. In this poster, they describe the fabrication and characterization techniques. They include discussion of current targets under development as well as target fabrication capabilities. Advanced target designs are fabricated by Sandia National Laboratories in cooperation with General Atomics of San Diego, CA and W.J. Schafer Associates, Inc. of Livermore, CA

  8. Monitoring in-vitro bovine embryo development during the first days after fertilization (Conference Presentation) (United States)

    Kandel, Mikhail E.; Rubessa, Marcello; Fernandes, Daniel; Nguyen, Tan H.; Wheeler, Matthew B.; Popescu, Gabriel


    Conventional label-based contrast enhancement techniques (e.g., fluorescence) frequently modify the genetic makeup of tagged cells, making them poor candidates for use in in-vitro fertilization applications. Instead, we choose a label-free form of contrast, based on interferometric imaging, sensitive to optical path length differences. Compared to, single HeLa cells, typical mammalian ova and embryos are more than an order of magnitude thicker. As a result, regions of large phase variation lead to phase wrapping and an overall reduction in signal intensity occurs due to multiple scattering. These effects manifest themselves in low-spatial frequencies (blurs), with the desired details buried in the background. We present a phase shifting interferometer that yields the derivative of the phase, a quantity whose value is particularly sensitive to local variations and fine details. We demonstrate that our new real-time imaging platform is valuable in measuring the multiday development of bovine embryos. Reconstructing the derivative of the image phase and amplitude, we characterize the motion of previously low-contrast structures, which are relevant for embryo viability tests.

  9. An illustrated landslide handbook for developing nations (United States)

    Highland, Lynn M.; Bobrowsky, Peter


    As landslides continue to be a hazard that account for large numbers of human and animal casualties, property loss, and infrastructure damage, as well as impacts on the natural environment, it is incumbent on developed nations that resources be allocated to educate affected populations in less developed nations, and provide them with tools to effectively manage this hazard. Given that the engineering, planning and zoning, and mitigation techniques for landslide hazard reduction are more accessible to developed nations, it is crucial that such landslide hazard management tools be communicated to less developed nations in a language that is not overly technical, and provides information on basic scientific explanations on where, why and how landslides occur. The experiences of the United States, Canada, and many other nations demonstrate that, landslide science education, and techniques for reducing damaging landslide impacts may be presented in a manner that can be understood by the layperson. There are various methods through which this may be accomplished–community-level education, technology transfer, and active one-on-one outreach to national and local governments, and non-governmental organizations (NGOs), who disseminate information throughout the general population. The population at large can also benefit from the dissemination of landslide information directly to individual community members. The United States Geological Survey and the Geological Survey of Canada have just published and will distribute a universal landslide handbook that can be easily made available to emergency managers, local governments, and individuals. The handbook, “The Landslide Handbook: A Guide to Understanding Landslides” is initially published as U.S. Geological Survey Circular 1325, in English, available in print, and accessible on the internet. It is liberally illustrated with schematics and photographs, and provides the means for a basic understanding of landslides, with

  10. Effect of Somatic Cell Types and Culture Medium on in vitro Maturation, Fertilization and Early Development Capability of Buffalo Oocytes

    Directory of Open Access Journals (Sweden)

    H. Jamil*, H. A. Samad, N. Rehman, Z. I. Qureshi and L. A. Lodhi


    Full Text Available This study was designed to evaluate the efficacy of different somatic cell types and media in supporting in vitro maturation (IVM, in vitro fertilization (IVF and early embryonic development competence of buffalo follicular oocytes. Cumulus oocyte complexes were collected for maturation from follicles (>6mm of buffalo ovaries collected at the local abattoir. Oocytes were co-cultured in tissue culture medium (TCM-199 with either granulosa cells, cumulus cells, or buffalo oviductal epithelial cells (BOEC @ 3x106 cells/ml or in TCM-199 without helper cells (control at 39°C and 5%CO2 in humidified air. Fresh semen was prepared in modified Ca++ free Tyrode medium. Fertilization was carried out in four types of media: i Tyrode lactate albumin pyruvate (TALP, ii TALP+BOEC, iii modified Ca++ free Tyrode and iv modified Ca++ free Tyrode+BOEC. Fertilized oocytes were cultured for early embryonic development in TCM-199 with and without BOEC. Higher maturation rates were observed in the granulosa (84.24% and cumulus cells (83.44% than BOEC co culture system (73.37%. Highest fertilization rate was obtained in modified Ca++ free Tyrode with BOEC co culture (70.42%, followed by modified Ca++ free Tyrode alone (63.77%, TALP with BOEC (36.92% and TALP alone (10.94%. Development of early embryos (8-cell stage improved in TCM-199 with BOEC co culture than TCM-199 alone. From the results of this study, it can be concluded that addition of somatic cells (granulosa cells, cumulus cells results in higher maturation rates of buffalo follicular oocytes than BOEC co culture system, while fertilization rate improved in modified Ca++ free Tyrode with and without BOEC. Addition of BOEC to TCM-199 improved the developmental capacity of early embryo.

  11. [Fertility preservation, contraception and menopause hormone therapy in women treated for rare ovarian tumors: Guidelines from the French national network dedicated to rare gynaecological cancer]. (United States)

    Rousset-Jablonski, Christine; Selle, Fréderic; Adda-Herzog, Elodie; Planchamp, François; Selleret, Lise; Pomel, Christophe; Chabbert-Buffet, Nathalie; Daraï, Emile; Pautier, Patricia; Trémollières, Florence; Guyon, Frederic; Rouzier, Roman; Laurence, Valérie; Chopin, Nicolas; Faure-Conter, Cécile; Bentivegna, Enrica; Vacher-Lavenu, Marie-Cécile; Lhomme, Catherine; Floquet, Anne; Treilleux, Isabelle; Lecuru, Fabrice; Gouy, Sébastien; Kalbacher, Elsa; Genestie, Catherine; de la Motte Rouge, Thibault; Ferron, Gwenael; Devouassoux-Shisheboran, Mojgan; Kurtz, Jean-Emmanuel; Namer, Moise; Joly, Florence; Pujade-Lauraine, Eric; Grynberg, Michael; Querleu, Denis; Morice, Philippe; Gompel, Anne; Ray-Coquard, Isabelle


    Rare ovarian tumors include complex borderline ovarian tumors, sex-cord tumors, germ cell tumors, and rare epithelial tumors. Indications and modalities of fertility preservation, infertility management and contraindications for hormonal contraception or menopause hormone therapy are frequent issues in clinical practice. A panel of experts from the French national network dedicated to rare gynaecological cancers, and of experts in reproductive medicine and gynaecology have worked on guidelines about fertility preservation, contraception and menopause hormone therapy in women treated for ovarian rare tumors. A panel of 39 experts from different specialties contributed to the preparation of the guidelines, following the DELPHI method (formal consensus method). Statements were drafted after a systematic literature review, and then rated through two successive rounds. Thirty-five recommendations were selected, and concerned indications for fertility preservation, contraindications for ovarian stimulation (in the context of fertility preservation or for infertility management), contraceptive options (especially hormonal ones), and menopause hormone therapy for each tumor type. Overall, prudence has been recommended in the case of potentially hormone-sensitive tumors such as sex cord tumors, serous and endometrioid low-grade adenocarcinomas, as well as for high-risk serous borderline ovarian tumors. In the context of a scarce literature, a formal consensus method allowed the elaboration of guidelines, which will help clinicians in the management of these patients. Copyright © 2017 Société Française du Cancer. Published by Elsevier Masson SAS. All rights reserved.

  12. Idaho National Engineering Laboratory site development plan

    Energy Technology Data Exchange (ETDEWEB)


    This plan briefly describes the 20-year outlook for the Idaho National Engineering Laboratory (INEL). Missions, workloads, worker populations, facilities, land, and other resources necessary to fulfill the 20-year site development vision for the INEL are addressed. In addition, the plan examines factors that could enhance or deter new or expanded missions at the INEL. And finally, the plan discusses specific site development issues facing the INEL, possible solutions, resources required to resolve these issues, and the anticipated impacts if these issues remain unresolved.

  13. Idaho National Engineering Laboratory site development plan

    International Nuclear Information System (INIS)


    This plan briefly describes the 20-year outlook for the Idaho National Engineering Laboratory (INEL). Missions, workloads, worker populations, facilities, land, and other resources necessary to fulfill the 20-year site development vision for the INEL are addressed. In addition, the plan examines factors that could enhance or deter new or expanded missions at the INEL. And finally, the plan discusses specific site development issues facing the INEL, possible solutions, resources required to resolve these issues, and the anticipated impacts if these issues remain unresolved


    Directory of Open Access Journals (Sweden)

    E. V. Zaytseva


    Full Text Available Rapid development of national payment systems (NPS is determined with such main factors as globalization of economic relations, application of newest information technologies, structural changes in the banking sphere and growth of the role of central banks. NPS should be considered as integral functional and institutional component of the country’s monetary system. Among main criteria that determine NPS development possibility there are its integrity, stability and flexibility. NPS may be regarded at as structure composed of the basic, organizational and regulating blocks.

  15. Fertilization compatibility of spawning corals (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — This data set includes experimental results of fertilization assays to characterize genetic compatibility between individual parental genotypes. Targeted species...

  16. Armed Forces and National Development in Korea (United States)


    Politically the most significant feature of the process of acculturation within the military is that it usually provides some form of training in...sheets. By maintaining certain level of temperature, moisture, light and soil fertility, such vegetables and berries as previously could only be enjoyed

  17. Below Replacement-Level Fertility in Conditions of slow Social and Economic Development: A Review of the Evidence from South-India

    Directory of Open Access Journals (Sweden)

    Minna Säävälä


    Full Text Available Demographic interest in the explanations of the first fertility transition has receded considerably during the last decade. Despite the empirical evidence of global convergence in fertility, there is still no consensus on the factors which explain the swiftness of the change in some contexts and its deceleration in some others. From the policy perspective, it remains pivotal to locate the factors that affect the momentum of fertility transition. In this essay the fast decline to below replacement-level period Total Fertility Rate in South India will be examined as an example of fertility transition despite slow social and/or economic development. The analysis is based on a literature review of empirical studies on the determinants of regional fertility differentials in India. Some southern states, most particularly Andhra Pradesh, manifest below replacement-level fertility (TFR 1.79 despite low average age at marriage even in Indian terms, the resilience of womens universal marriage, and heavy reliance on a terminal family planning method, female sterilization. The case of Andhra Pradesh shows that below-replacement level fertility can occur despite slow social development, widespread poverty and gender asymmetries. Geographical and social diffusion effects are partly responsible of the speed of the decline, although they are difficult to measure or test in the level of fertility decision-making.

  18. Soil fertility and the role of soils for food security in developing countries (United States)

    Tittonell, Pablo


    Addressing current and future food security is not just a matter of producing more food globally. Agricultural productivity must increase where food is most needed, and where both rural and urban populations are expected to increase the fastest in the near future. This is the situation in most of sub-Saharan Africa and in several other regions of Latin America, Asia and the Pacific. There are some common denominators to these regions. In the first place, the inability of the majority of farmers to access and/or to afford agricultural inputs. Second, the severity with which climate change impacts on some of these regions. Third, the extent of soil degradation, which is estimated at 25% of the arable land in the world. And finally, the fact that some of these regions are hosting valuable biodiversity and/or delivering ecosystem services of global or regional importance, which often leads to competing claims between the local and international communities. It has been repeatedly shown that the technologies of industrial agriculture as practiced in developed regions are ineffective at sustaining soil productivity in the context of smallholder family agriculture. Restoring soil productivity and ecosystem functions in these contexts requires new ways of managing soil fertility. These include: (i) innovative forms of 'precision' agriculture that consider the diversity, heterogeneity and dynamics of smallholder farming systems; (ii) a systems approach to nutrient acquisition and management; (iii) agroecological strategies for the restoration of degraded soils and the maintenance of soil physical properties; and (iv) to capitalize on the recent and growing understanding on soil trophic networks to increase nutrient and water use efficiency. I will provide examples on advances in these fronts, and discuss the challenges ahead their broad implementation by farmers in developing regions.

  19. From Fertilization to Birth: Representing Development in High School Biology Textbooks (United States)

    Wellner, Karen L.

    Biology textbooks are everybody's business. In accepting the view that texts are created with specific social goals in mind, I examined 127 twentieth-century high school biology textbooks for representations of animal development. Paragraphs and visual representations were coded and placed in one of four scientific literacy categories: descriptive, investigative, nature of science, and human embryos, technology, and society (HETS). I then interpreted how embryos and fetuses have been socially constructed for students. I also examined the use of Haeckel's embryo drawings to support recapitulation and evolutionary theory. Textbooks revealed that publication of Haeckel's drawings was influenced by evolutionists and anti-evolutionists in the 1930s, 1960s, and the 1990s. Haeckel's embryos continue to persist in textbooks because they "safely" illustrate similarities between embryos and are rarely discussed in enough detail to understand comparative embryology's role in the support of evolution. Certain events coincided with changes in how embryos were presented: (a) the growth of the American Medical Association (AMA) and an increase in birth rates (1950s); (b) the Biological Sciences Curriculum Study (BSCS) and public acceptance of birth control methods (1960s); (c) Roe vs. Wade (1973); (d) in vitro fertilization and Lennart Nilsson's photographs (1970s); (e) prenatal technology and fetocentrism (1980s); and (f) genetic engineering and Science-Technology-Society (STS) curriculum (1980s and 1990s). By the end of the twentieth century, changing conceptions, research practices, and technologies all combined to transform the nature of biological development. Human embryos went from a highly descriptive, static, and private object to that of sometimes contentious public figure. I contend that an ignored source for helping move embryos into the public realm is schoolbooks. Throughout the 1900s, authors and publishers accomplished this by placing biology textbook embryos and

  20. Globalization and Contemporary Fertility Convergence. (United States)

    Hendi, Arun S


    The rise of the global network of nation-states has precipitated social transformations throughout the world. This article examines the role of political and economic globalization in driving fertility convergence across countries between 1965 and 2009. While past research has typically conceptualized fertility change as a country-level process, this study instead employs a theoretical and methodological framework that examines differences in fertility between pairs of countries over time. Convergence in fertility between pairs of countries is hypothesized to result from increased cross-country connectedness and cross-national transmission of fertility-related schemas. I investigate the impact of various cross-country ties, including ties through bilateral trade, intergovernmental organizations, and regional trade blocs, on fertility convergence. I find that globalization acts as a form of social interaction to produce fertility convergence. There is significant heterogeneity in the effects of different cross-country ties. In particular, trade with rich model countries, joint participation in the UN and UNESCO, and joining a free trade agreement all contribute to fertility convergence between countries. Whereas the prevailing focus in fertility research has been on factors producing fertility declines, this analysis highlights specific mechanisms-trade and connectedness through organizations-leading to greater similarity in fertility across countries. Globalization is a process that propels the spread of culturally laden goods and schemas impinging on fertility, which in turn produces fertility convergence.

  1. Development of national immunoassay reagent programmes

    International Nuclear Information System (INIS)

    Sufi, S.B.; Micallef, J.V.; Ahsan, R.; Goncharov, N.P.


    Despite the existence of networks of fully equipped laboratories with well-trained staff, the availability of immunodiagnostic services in developing countries is often limited by the high cost of imported kits. There are a number of ways of tackling this problem, ranging from bulk purchase of kits or reagents to local development and production of assay systems. Argentina/Chile, China, Cuba/Mexico, and Thailand are amongst the countries which have established local immunoassay reagent programmes to manufacture low cost, high quality immunoassay reagents. Kits from these projects are now beginning to become available, and it is hoped that they will promote national diagnostic services and research, as well as stimulating the development of reagent programmes for other analytes. (author). 4 refs, 1 tab

  2. Symposium on irradiation for national development. Proceedings

    International Nuclear Information System (INIS)

    Adesanmi, C.A.; Ogbadu, G.H.


    This document is the full proceedings of the symposium on irradiation for national development held at SHESTCO in 1996. It contains the full texts of a forward, opening and special remarks, welcome and keynote addresses and abstracts and texts of 23 technical papers. The subjects covered included regulations, codes of practice, irradiation technology in food, agriculture and industry, radiation protection and dosimetry. The questions, answers and comments in the discussion sessions are also included. Additionally, the abstracts of 8 other papers are included. We wish to thank the Coordinator of SHESTCO for making available this proceedings

  3. Endogenous and exogenous factors in national development ...

    African Journals Online (AJOL)

    Endogenous and exogenous factors in national development: inferences from the metaphor of witchcraft (Àjé) in Olátúbòsún. Oládàpò's poetry. This work engages political commentary in the work of Olátúbòsún Oládàpò, a Yorùbá poet. Its focus is on the way that political ideas and values that are rooted in Nigerian culture ...

  4. Fertilizer trends

    Energy Technology Data Exchange (ETDEWEB)

    Donaldson, R.


    This fourteenth edition of Fertilizer Trends presents historical fertilizer market data to aid industry, government, and financial market analysis and planners in their study of fertilizer and agricultural market cycles, market planning, and investment decisions. A 27-year summary of the US fertilizer market is presented in graphic and tabular form. Production, use, and trade data are included for each plant nutrient and sulfur. Canadian statistics have been included because of the important role of the Canadian fertilizer industry in the US fertilizer market. World production and consumption of nitrogen, phosphate, and potash are included because of the strong influence of world markets on the domestic market. Planted acreage and plant nutrient application rates for the major crops have been included to illustrate their effect on fertilizer use. Retail prices of the leading US fertilizer materials also are given.

  5. Essential role of maternal UCHL1 and UCHL3 in fertilization and preimplantation embryo development

    Czech Academy of Sciences Publication Activity Database

    Mtango, N.R.; Sutovsky, M.; Šušor, Andrej; Zhong, Z.S.; Latham, K.E.; Šutovský, P.


    Roč. 227, č. 4 (2012), s. 1592-1603 ISSN 0021-9541 R&D Projects: GA ČR GA524/07/1087 Institutional research plan: CEZ:AV0Z50450515 Keywords : UBIQUITIN-PROTEASOME PATHWAY * ANTI-POLYSPERMY DEFENSE * IN-VITRO FERTILIZATION Subject RIV: ED - Physiology Impact factor: 4.218, year: 2012

  6. Development Of Silica Potassium Fertilizers From Trass Rock With Calcination Process (United States)

    Wahyusi, KN; Siswanto


    Rocks and sand mines have important benefits for life. With the many benefits of rocks, it is a pity if Indonesia has a lot of raw material reserves waste it. Examples of the benefits of rocks that can be converted into silica potassium fertilizer by reacting with potassium hydroxide. Examples of rocks that can be taken trass rock. The procedure for making silica potassium is by reacting 100 mesh trass rock with KOH and K2CO3 reagents whose composition is arranged by weight ratio, where the base of the trass rock is 100 gr. The process is carried out at a temperature of 1.250 °C with a reaction time of 1 hour. The results obtained are the best silica potassium fertilizer for K2CO3 reagent which is 500gr: 74gr with SiO2 content: 26.8% and K2O content: 27.3%, with water solubility 24.02%, while for silica potassium fertilizer product from The best trass rock for KOH reagent is with a mol ratio of 400 gr : 60 gr with SiO2 content : 23.6% and K2O content: 22.2%, with 25.65% water solubility. The pore size of silica potassium fertilizer product of this trass rock, the range 350 - 1000 nm.

  7. Development of new historical global Nitrogen fertilizer map and the evaluation of their impacts on terrestrial N cycling and the evaluation of their impacts on terrestrial N cycling (United States)

    Nishina, K.; Ito, A.; Hayashi, S.


    The use of synthetic nitrogen fertilizer was rapidly growing up after the birth of Haber-Bosch process in the early 20th century. The recent N loading derived from these sources on terrestrial ecosystems was estimated 2 times higher than biogenic N fixation in terrestrial ecosystems (Gruber et al., 2009). However, there are still large uncertainties in cumulative N impacts on terrestrial impact at global scale. In this study, to assess historical N impacts at global scale, we made a new global N fertilizer input map, which was a spatial-temporal explicit map (during 1960-2010) and considered the fraction of NH4+ and NO3- in the N fertilizer inputs. With the developed N fertilizer map, we evaluated historical N20 cycling changes by land-use changes and N depositions in N cycling using ecosystem model 'VISIT'. Prior to the downscaling processes for global N fertilizer map, we applied the statistical data imputation to FAOSTAT data due to there existing many missing data especially in developing countries. For the data imputation, we used multiple data imputation method proposed by Honaker & King (2010). The statistics of various types of synthetic fertilizer consumption are available in FAOSTAT, which can be sorted by the content of NH4+ and NO3-, respectively. To downscaling the country by country N fertilizer consumptions data to the 0.5˚x 0.5˚ grid-based map, we used historical land-use map in Earthstat (Rumankutty et al., 1999). Before the assignment of N fertilizer in each grid, we weighted the double cropping regions to be more N fertilizer input on to these regions. Using M3-Crops Data (Monfreda et al., 2008), we picked up the dominant cropping species in each grid cell. After that, we used Crop Calendar in SAGE dataset (Sacks et al., 2010) and determined schedule of N fertilizer input in each grid cell using dominant crop calendar. Base fertilizer was set to be 7 days before transplanting and second fertilizer to be 30 days after base fertilizer application

  8. Radioimmunoassay of hormones for clinical trials of fertility regulating agents in developing countries

    International Nuclear Information System (INIS)


    The need for accurate hormonal assay is emphasized, and becomes more urgent as hormones, in addition to their conventional medical use are being increasinly used for family planning purposes, particularly in developing countries. Readily available facilities and laboratories for the assay of hormone strength are therefore required, and also for the standardization of methods and techniques for such assays. Radioimmunology appears and excellent tool for this. Analytical techniques in actual use and techniques of potential future use are considered. Techniques for assessing hormone strength, potenty and doses are outlined. Criteria are developed, required for establishing a calibration and standardization laboratory for hormone strength. These criteria include a discussion of the necessary staff, location of such a facility and the material and equipment needed. Help from consultants, staff training, and the growth in sample analysis and corresponding financial aspects are discussed. Finally, the problems are reviewed of creating national laboratories which can be developed as services available for certain geographical regions

  9. Effect of sericin supplementation during in vitro maturation on the maturation, fertilization and development of porcine oocytes. (United States)

    Do, L T K; Namula, Z; Luu, V V; Sato, Y; Taniguchi, M; Isobe, T; Kikuchi, K; Otoi, T


    This study aimed to examine the effects of sericin supplementation during in vitro oocyte maturation on the nuclear maturation, fertilization and development of porcine oocytes. Cumulus-oocyte complexes (COCs) were cultured in maturation medium supplemented with 0 (control), 0.1, 0.5, 1.0, 2.5 or 5.0% sericin and were then subjected to in vitro fertilization and embryo culture. More COCs matured with 1.0% sericin underwent germinal vesicle breakdown and reached metaphase II compared with the control COCs matured without sericin (p sericin level. The total fertilization rate of oocytes matured with 1.0% sericin was higher (p sericin. Supplementation with more than 1.0% sericin decreased the DNA fragmentation index of the blastocysts compared with the control group (p sericin had no beneficial effects on the cleavage, development to the blastocyst stage and the total cell number of the embryos. Our findings indicate that supplementation with 1.0% sericin during maturation culture may improve the nuclear maturation and the quality of the embryos but does not affect blastocyst formation. © 2014 Blackwell Verlag GmbH.

  10. The functional role of insulin in fertility and embryonic development-What can we learn from the bovine model? (United States)

    Laskowski, D; Sjunnesson, Y; Humblot, P; Andersson, G; Gustafsson, H; Båge, R


    Insulin is a key metabolic hormone that plays a crucial role in regulating energy homeostasis in the body. In addition, insulin-dependent signaling has important functions in reproduction and early embryo development. As metabolism and reproduction are closely linked, metabolic challenges may be the source of reproductive disorders and decreased fertility. This is known for the dairy cow and for other species including the human. Although metabolic disorders in the dairy cow often derive from a failure to adapt to a high milk production, the situation in the human is often linked to emerging conditions and associated diseases in our modern society such as obesity and diabetes, where an excess energy intake causes decreased fertility in women. Both energy excess and energy deficit are associated with a deviation of insulin concentrations in serum and follicular fluid from normal levels. Although many studies have shown that extreme variation in energy supply can negatively influence early embryo development by inducing changes in circulating concentrations of several metabolites or hormones like insulin, several in vitro culture media are still supplemented with insulin in high concentrations. In this review, direct and indirect effects of insulin on fertility will be described. Differences between the in vivo and in vitro situations will also be discussed. Copyright © 2016 Elsevier Inc. All rights reserved.

  11. [Fertility transition in Peru]. (United States)

    Ferrando, D; Aramburu, C E


    Data from national censuses and sample surveys are the basis for this examintion of differential fertility and the fertility transition in Peru. Changes in the level and structure of fertility in the 3 major geographic regions are compared, and the role of contraceptive usage and nuptiality changes in the fertility decline are analyzed. Peru's total fertility rate was estimated at 6.85 in 1965 and has since declined to 6.56 in 1965-70, 6.00 in 1970-75, 5.30 in 1975-80, 4.65 in 1980-85, and 4.00 in 1985-90. The fertility decline varied in intensity and timing in the geographic regions. A clear fertility decline began among upper and middle income groups in the principal cities in the 1960s, spreading gradually to the urban low income sectors. Not until the late 1970s did the fertility decline spread to the rest of the population, coinciding with the years of severe economic crisis. The urban total fertility rate declined from 6 to 3.77 during 1961-86, but rural fertility increased through 1972 to 8.12, before declining slightly to 7.62 in 1981 and more markedly to 6.65 in 1986. Sociocultural and economic differences between Peru's natural regions are appreciable, and account for the contrasts in fertility trends. The greatest changes occurred in metropolitan Lima, which already had relatively low fertility in 1961. Its total fertility rate declined 44% from 5.6 in 1961 to 3.13 in 1986. Fertility declined by slightly under 40% in the rest of the coast, by almost 25% in the jungle, and by scarcely 14% in the sierra. The total fertility rates in 1961 and 1986, respectively, were 6.38 and 4.13 on the coast, 6.64 and 6.45 in the highlands, and 7.92 and 5.97 in the lowlands. The fertility decline, especially in the lower classes, was a response initially to the process of cultural modernization which in slightly over 2 decades saw a profound transformation of Peru from a rural, Andean, illiterate, and agrarian society to an urban, coastal, literate, and commercial society

  12. Development of national safeguards inspection technology

    Energy Technology Data Exchange (ETDEWEB)

    Kwack, Eun Ho; You, Keon Jung; Kim, Jin Su [and others


    It is considered that the safeguards trend in the IAEA and international nonproliferation regime is being accelerated toward strengthened safeguards system. In order to effectively respond to the stream as a whole, government has to have a firm policy-intention on nuclear non-proliferation, and supporting stance as to the stream should be taken consistently. Also, technological development satisfying the non-proliferation requirement would be pursued for the establishment of transparency and the enhancement of international confidence. At present, Korea stands at take-off stage in terms of safeguards. Therefore, necessary measures such as arrangement of legal framework, staffing and training of inspection man-power, and purchase of inspection equipment should be taken at the same time for earlier settlement of national safeguards system. In this connection, international cooperation with the share of the inspection results and equipment between the IAEA and TCNC is demanded. In the long term, the development of inspection technology as well as the research of sophisticated technology will have to be pursued. Emphasis should be placed on the regional safeguards system as well. In addition, it is necessary to ensure internationally that nuclear technological development to be planned is development of safeguards technology. (author). 20 tabs., 24 figs., 45 refs.

  13. National Integration in Humanities and Development: The Way ...

    African Journals Online (AJOL)

    This paper examines the following concepts nation and its attributes; national integration, development and social studies education. The paper also discusses the concept of national integration, theories of nation al integration and the problems of national integration in Nigeria. It further discusses the factors of disunity and ...

  14. Effects of the toxic benthic dinoflagellate Ostreopsis cf. ovata on fertilization and early development of the sea urchin Lytechinus variegatus. (United States)

    Neves, Raquel A F; Contins, Mariana; Nascimento, Silvia M


    Blooms of the benthic dinoflagellate Ostreopsis cf. ovata have been recorded with increasing frequency, intensity and geographic distribution. This dinoflagellate produces potent toxins that may cause mortality of marine invertebrates. Adults of sea urchins are commonly affected by O. cf. ovata exposure with evidence of spines loss and high mortality during periods of high dinoflagellate abundances. Here, we report on the effects of the toxic dinoflagellate O. cf. ovata on fertilization and early development of the sea urchin Lytechinus variegatus, a key ecological herbivore. Lytechinus variegatus eggs and sperm were experimentally exposed to different concentrations of Ostreopsis cf. ovata (4, 40, 400, and 4000 cells ml -1 ) to test the hypothesis that fertilization success, embryonic and larval development of the sea urchin are negatively affected by the toxic dinoflagellate even at low abundances. Reduced fertilization, developmental failures, embryo and larval mortality, and occurrence of abnormal offspring were evident after exposure to O. cf. ovata. Fertilization decreased when gametes were exposed to high O. cf. ovata abundances (400 and 4000 cells ml -1 ), but just the exposure to the highest abundance significantly reduced fertilization success. Sea urchin early development was affected by O. cf. ovata in a dose-dependent way, high dinoflagellate abundances fully inhibited the early development of L. variegatus. Ostreopsis cf. ovata significantly increased the mortality of sea urchin eggs and embryos in the first hours of exposure (∼1-3 h), regardless of dinoflagellate abundance. Abundances of 400 and 4000 O. cf. ovata cells ml -1 induced significantly higher mortality on sea urchin initial stages in the first hours, and no egg or embryo was found in these treatments after 18 h of incubation. The early echinopluteus larva was only reached in the control and in treatments with low Ostreopsis cf. ovata abundances (4 and 40 cells ml -1 ). The

  15. National Health Accounts development: lessons from Thailand. (United States)

    Tangcharoensathien, V; Laixuthai, A; Vasavit, J; Tantigate, N A; Prajuabmoh-Ruffolo, W; Vimolkit, D; Lertiendumrong, J


    National Health Accounts (NHA) are an important tool to demonstrate how a country's health resources are spent, on what services, and who pays for them. NHA are used by policy-makers for monitoring health expenditure patterns; policy instruments to re-orientate the pattern can then be further introduced. The National Economic and Social Development Board (NESDB) of Thailand produces aggregate health expenditure data but its estimation methods have several limitations. This has led to the research and development of an NHA prototype in 1994, through an agreed definition of health expenditure and methodology, in consultation with peer and other stakeholders. This is an initiative by local researchers without external support, with an emphasis on putting the system into place. It involves two steps: firstly, the flow of funds from ultimate sources of finance to financing agencies; and secondly, the use of funds by financing agencies. Five ultimate sources and 12 financing agencies (seven public and five private) were identified. Use of consumption expenditures was listed under four main categories and 32 sub-categories. Using 1994 figures, we estimated a total health expenditure of 128,305.11 million Baht; 84.07% consumption and 15.93% capital formation. Of total consumption expenditure, 36.14% was spent on purchasing care from public providers, with 32.35% on private providers, 5.93% on administration and 9.65% on all other public health programmes. Public sources of finance were responsible for 48.79% and private 51.21% of the total 1994 health expenditure. Total health expenditure accounted for 3.56% of GDP (consumption expenditure at 3.00% of GDP and capital formation at 0.57% of GDP). The NESDB consumption expenditure estimate in 1994 was 180,516 million Baht or 5.01% of GDP, of which private sources were dominant (82.17%) and public sources played a minor role (17.83%). The discrepancy of consumption expenditure between the two estimates is 2.01% of GDP. There

  16. In vitro fertilization and artificial activation of eggs of the direct-developing anuran Eleutherodactylus coqui

    Directory of Open Access Journals (Sweden)

    Toro Esteban


    Full Text Available Abstract Although much is known about the reproductive biology of pond-breeding frogs, there is comparatively little information about terrestrial-breeding anurans, a highly successful and diverse group. This study investigates the activation and in vitro fertilization of eggs of the Puerto Rican coqui frog obtained by hormonally induced ovulation. We report that spontaneous activation occurs in 34% of eggs, probably in response to mechanical stress during oviposition. Artificial activation, as evidenced by the slow block to polyspermy and the onset of zygote division, was elicited both by mechanical stimulation and calcium ionophore exposure in 64% and 83% of the cases, respectively. Finally, one in vitro fertilization protocol showed a 27% success rate, despite the fact that about one third of all unfertilized eggs obtained by hormone injection auto-activate. We expect these findings to aid in the conservation effort of Eleutherodactylus frogs, the largest vertebrate genus.

  17. Education for Self-Reliance: An Imperative for National Development

    African Journals Online (AJOL)

    So many reasons have been given for why most Third World Nations continue to be on the periphery of national development. So many measures have also been suggested as ways of dealing with the problem of national development. This paper sees education as a potent instrument with which the problem of national ...

  18. Use of Bio-Organic Fertilizers to Develop N Uptake Using 15N Technique

    International Nuclear Information System (INIS)

    Galal, Y.G.M.


    Experimental work either in field scale or in green house conditions were conducted using 15 N technique to evaluate the role of different bio fertilizers and different plant residues as organic amendments on enhancement of plant N nutrition. Nitrogen fixation by a symbiotic bacteria has been observed in greenhouse and field experiments under dry land cropping systems. Biological N 2 fixation associated with crop residues (legumes or cereals) was investigated in pot experiments with wheat and chickpea cultivars. In these experiments, labelled wheat and rice straw were used as organic N sources in comparison with either 15 N-labelled ammonium sulfate or ammonium nitrate as chemical nitrogen fertilizers. Rhizobium inoculation extended to be used with wheat gave the best results of N uptake and N 2 fixation when combined with Azospirillum brasilense as heterotrophic diazotrophs. The nitrogen uptake by wheat plants was significantly increased by application of soybean residues and inoculation with Azospirillum brasilense. From the field trial we can conclude that soybean residue as enriched N material, and Azospirillum brasilense inoculation enhanced N yields of wheat cultivars grown in poor fertile sandy soil

  19. Development of a rapid and efficient microinjection technique for gene insertion into fertilized salmonid eggs

    Energy Technology Data Exchange (ETDEWEB)

    Chandler, D.P.; Welt, M.; Leung, F.C.


    An efficient one-step injection technique for gene insertion into fertilized rainbow trout (Oncorhynchus mykiss) eggs is described, and basic parameters affecting egg survival are reported. Freshly fertilized rainbow trout eggs were injected in the perivitelline space with a recombinant mouse metallothionein-genomic bovine growth hormone (bGH) DNA construct using a 30-gauge hypodermic needle and a standard microinjection system. Relative to control, site of injection and DNA concentration did not affect the egg survival, but injections later than 3--4 hours post fertilization were detrimental. The injection technique permitted treatment of 100 eggs/hr with survivals up to 100%, resulting in a 4% DNA uptake rate as indicated by DNA dot blot analysis. Positive dot blot results also indicated that the injected DNA is able to cross the vitelline membrane and persist for 50--60 days post hatching, obviating the need for direct injection into the germinal disk. Results are consistent with previous transgenic fish work, underscoring the usefulness of the technique for generating transgenic trout and salmonids. 24 refs., 6 figs., 3 tabs.

  20. [Martin Klesment. Fertility development in Estonia during the second half of the XX century: the economic context and its implications] / Olaf Mertelsmann

    Index Scriptorium Estoniae

    Mertelsmann, Olaf, 1969-


    Arvustus: Martin Klesment. Fertility development in Estonia during the second half of the XX century: the economic context and its implications. Tallinn: Tallinna Ülikool, 2010. (Tallinna Ülikooli sotsiaalteaduste dissertatsioonid, 46)

  1. Parental Infertility, Fertility Treatment, and Childhood Epilepsy

    DEFF Research Database (Denmark)

    Kettner, Laura O.; Ramlau-Hansen, Cecilia H.; Kesmodel, Ulrik S.


    BACKGROUND: A few studies have indicated an increased risk of epilepsy in children conceived by fertility treatment possibly due to characteristics of the infertile couple rather than the treatment. We therefore aimed to investigate the association between parental infertility, fertility treatment......, and epilepsy in the offspring, including the subtypes of epilepsy; idiopathic generalised epilepsy and focal epilepsy. METHODS: This cohort included all pregnancies resulting in liveborn singletons from the Aarhus Birth Cohort, Denmark (1995-2013). Information on time to pregnancy and fertility treatment...... was obtained from pregnancy questionnaires in early pregnancy. Children developing epilepsy were identified from the Danish National Patient Register and the Danish National Prescription Registry until 2013. Data were analysed using Cox proportional hazards regression adjusted for potential confounders...

  2. Development of a health promotion programme to improve awareness of factors that affect fertility, and evaluation of its reach in the first 5 years

    Directory of Open Access Journals (Sweden)

    Karin Hammarberg


    Full Text Available Awareness among people of reproductive age about the factors that influence fertility and reproductive outcomes, including medically assisted reproduction outcomes, is generally low. To improve awareness about the potentially modifiable factors that affect fertility and reproductive outcomes, ‘Your Fertility’, a fertility health promotion programme funded by the Australian Government, was established in 2011. This paper describes the development and evaluation of the reach of the Your Fertility programme from its inception in 2011 to June 2016. Systematically recorded outcomes for the programme’s key focus areas and Google Analytics data were collated. Key achievements include developing and maintaining an internationally renowned website that experiences high growth and demand for fertility-related information; by 2016, over 5 million users had viewed more than 10 million webpages, and over 96,000 users had engaged in programme messages across social media. Programme messages have reached more than 4 million Australian social media users, and a potential audience of 150 million through media coverage across more than 320 media features. More than 4200 education and health professionals have completed online learning modules, and external partnerships have been established with 14 separate organizations. Data collected over 5 years indicate that the Your Fertility programme meets a need for targeted, evidence-based, accessible fertility-related information.

  3. A Trilogy of Philosophy, Language and National Development ...

    African Journals Online (AJOL)

    Against this broad canvass of national development, it is argued that man is the centre-piece of national development and, since the humanities play a leading role in the cultivation of man, no national development paradigm can be conceived and executed without the humanities, especially philosophy and language, ...

  4. Development of a Novel Space Flight Plan to Monitor Female Mice Fertility Using Reduced Crew Time (United States)

    Christenson, Lane; Hong, Xiaoman; Alwood, Joshua S.; Ronca, April E.; Tash, Joseph S.; Talyansky, Yuli


    Ovarian estrogen impacts the normal homeostatic and metabolic processes of all tissues and organ systems within the body: particularly, but not limited to canonical space-flight impacted systems: bone, muscle, immune, wound repair, and cardiovascular. Effects of space flight on the ovarian estrogen production are therefore critical to our understanding of all space flight experiments using female mice, the current paradigm being used on the International Space Station (ISS). Recently, we demonstrated that vaginal wall histology could be used to determine the stage of the estrous cycle in female mice at the time of sacrifice in space. Moreover, this robust technique was completed following two post-flight freezethaw procedures of the carcasses (RR1 experiment). Thus, this technique represents a viable mechanism to determine the estrous cycle status of the female at the time of sacrifice and can be completed in a manner that does not impact primary experimental objectives. We propose that vaginal wall histology become a standard procedure completed on all mice sacrificed in space and that the individual estrous status of each animal be shared with all investigators. While evidence of estrous cyclicity was present in long-term (33 day) RR1 mice, fertility of female mice exposed to weightlessness remains unknown. In preparation for an upcoming funded NASA flight investigating the effects of long duration spaceflight on female fertility, we have refined our experimental design to minimize crew flight time and to accommodate the duration of Dragon capsule berth. These refinements maintain all our proposed primary and secondary experimental objectives. Briefly, in order to evaluate fertility, we will super ovulate mice using standard procedures (PMSG hCG), followed by collection of reproductive tract after follicular stimulation alone (PMSG) or following ovulation (hCG). Ovarian folliculogenesis and ovulation rate will be determined in fixed tissues following return in

  5. Nuclear techniques in the development of fertilizer practices for multiple cropping systems

    International Nuclear Information System (INIS)


    This document summarizes the results of a coordinated research programme. Eight Member States of the FAO and IAEA carried out a series of field studies aimed at identifying optimum practices for the use of fertilizers in multiple cropping systems and for maximizing the contribution of atmospheric nitrogen biologically fixed by the legume component of such systems to the non-fixing cereal component or to the succeeding crop. Isotope techniques allowed the researchers to accurately determine the uptake of specific nutrients and to compare selected treatments

  6. A new look at the Asian fertility transition. (United States)

    Caldwell, J C


    The author describes the fertility transition in Asia. The Asian transition is surprising for its achievement of 45% of the population being under or around replacement level. The region has improved the opportunity for sustained education. The only country without controlled fertility in the world is Pakistan. Other Islamic countries have higher contraception rates. It is explained that Pakistan's lack of fertility transition may be due to strong male dominance and patriarchy and low levels of female education, which reinforce the dominance. Pakistan remains the outlier in the region, despite its having higher per capita income than Afghanistan, Nepal, Bhutan, Laos, and Cambodia. Bangladesh's experience shows that access to family planning (FP) has a significant role in fertility transition, but its provision of a variety of methods without charge was key to its success. FP has been a national priority since 1973, and there was no religious opposition at the national level. The civil service operated consistently in development priorities and policies despite political changes. By 1993, Bangladesh achieved almost universal primary schooling for girls. Bangladesh achieved a fertility of 3.6 in only 26 years compared to India, which has a higher per capita income. During the 1950s to the present, China and India accounted for 60% of the decline in the region. By the late 1960s, fertility decline was apparent throughout the region. The only countries that now show little fertility decline and fertility over 5 children/woman are Afghanistan, Laos, Cambodia, Nepal, and Pakistan. The Asian decline was unique.

  7. Geothermal materials development at Brookhaven National Laboratory

    Energy Technology Data Exchange (ETDEWEB)

    Kukacka, L.E. [Brookhaven National Lab., Upton, NY (United States)


    As part of the DOE/OGT response to recommendations and priorities established by industrial review of their overall R&D program, the Geothermal Materials Program at Brookhaven National Laboratory (BNL) is focusing on topics that can reduce O&M costs and increase competitiveness in foreign and domestic markets. Corrosion and scale control, well completion materials, and lost circulation control have high priorities. The first two topics are included in FY 1997 BNL activities, but work on lost circulation materials is constrained by budgetary limitations. The R&D, most of which is performed as cost-shared efforts with U.S. geothermal firms, is rapidly moving into field testing phases. FY 1996 and 1997 accomplishments in the development of lightweight CO{sub 2}-resistant cements for well completions; corrosion resistant, thermally conductive polymer matrix composites for heat exchange applications; and metallic, polymer and ceramic-based corrosion protective coatings are given in this paper. In addition, plans for work that commenced in March 1997 on thermally conductive cementitious grouting materials for use with geothermal heat pumps (GHP), are discussed.

  8. Observational study of the development and evaluation of a fertility preservation patient decision aid for teenage and adult women diagnosed with cancer: the Cancer, Fertility and Me research protocol. (United States)

    Jones, G L; Hughes, J; Mahmoodi, N; Greenfield, D; Brauten-Smith, G; Skull, J; Gath, J; Yeomanson, D; Baskind, E; Snowden, J A; Jacques, R M; Velikova, G; Collins, K; Stark, D; Phillips, R; Lane, S; Bekker, H L


    Women diagnosed with cancer and facing potentially sterilising cancer treatment have to make time-pressured decisions regarding fertility preservation with specialist fertility services while undergoing treatment of their cancer with oncology services. Oncologists identify a need for resources enabling them to support women's fertility preservation decisions more effectively; women report wanting more specialist information to make these decisions. The overall aim of the 'Cancer, Fertility and Me' study is to develop and evaluate a new evidence-based patient decision aid (PtDA) for women with any cancer considering fertility preservation to address this unmet need. This is a prospective mixed-method observational study including women of reproductive age (16 years +) with a new diagnosis of any cancer across two regional cancer and fertility centres in Yorkshire, UK. The research involves three stages. In stage 1, the aim is to develop the PtDA using a systematic method of evidence synthesis and multidisciplinary expert review of current clinical practice and patient information. In stage 2, the aim is to assess the face validity of the PtDA. Feedback on its content and format will be ascertained using questionnaires and interviews with patients, user groups and key stakeholders. Finally, in stage 3 the acceptability of using this resource when integrated into usual cancer care pathways at the point of cancer diagnosis and treatment planning will be evaluated. This will involve a quantitative and qualitative evaluation of the PtDA in clinical practice. Measures chosen include using count data of the PtDAs administered in clinics and accessed online, decisional and patient-reported outcome measures and qualitative feedback. Quantitative data will be analysed using descriptive statistics, paired sample t-tests and CIs; interviews will be analysed using thematic analysis. Research Ethics Committee approval (Ref: 16/EM/0122) and Health Research Authority approval

  9. Business Development of Solid Waste Treatment Technology and Bio-Fertilizer Production through a Danish-Vietnamese Partnership

    DEFF Research Database (Denmark)

    Christensen, David


    , legislative and market context. The findings are useful for researchers and practitioners within the waste sector in Southeast Asian countries. The partnership’s business concept deals with the proposed introduction of improved Danish solid waste separation and treatment technology at a plant in one......-fertilizer market to be financially sustainable....... forward through socially and culturally embedded negotiations among its actors, shaping the technology in question. Additionally, the business development process is seen in an institutional perspective, demonstrating how Danish technology transferal is capable of being adapted to the Vietnamese physical...

  10. Development of bioengineering processes to transform greenhouse waste into energy, fertilizer and tomato

    Energy Technology Data Exchange (ETDEWEB)

    Brisson, D.; Masse, D.I. [Agriculture and Agri-Food Canada, Lennoxville, PQ (Canada). Dairy and Swine Research and Development Centre; Juteau, P. [Quebec Univ., Laval, PQ (Canada). INRS-Institut Armand Frappier; Saint-Laurent CEGEP, Montreal, PQ (Canada). Centre des technologies de l' eau; Dorais, M. [Agriculture and Agri-Food Canada, Quebec City, PQ (Canada). Horticultural Research Centre


    Methods to promote sustainable production systems in greenhouses were discussed with particular reference to anaerobic digestion (AD) and nitrification processes for waste and nutrient management and energy consumption. The high cost of organic soluble fertilizers and the difficulty in obtaining a quality product are strong limitations for converting conventional greenhouses to organic practices. AD has been shown to be a promising solution for disposal of tomato leaves pruned during greenhouse operations. Studies have shown that AD generates end-products, notably supernatant sludge that have agronomic benefits of land application for forage and cereal crops. However, little has been done for horticultural crops. Unlike field crops, nitrification of digester effluents is a key step for using AD effluents as fertilizers for vegetable greenhouse plants. Greenhouse vegetables need nitrogen mainly under the nitrate form for an adequate growth because the other forms of nitrogen are detrimental to plant and fruit quality. However, nitrification of AD supernatant can be challenging because of its high ammonia content and its inhibition potential of nitrifying micro-organisms. This study examined the few nitrification processes that have the potential to operate under these conditions.

  11. Rat fertility and embryo fetal development: influence of exposure to the Wi-Fi signal. (United States)

    Poulletier de Gannes, Florence; Billaudel, Bernard; Haro, Emmanuelle; Taxile, Murielle; Le Montagner, Laureline; Hurtier, Annabelle; Ait Aissa, Saliha; Masuda, Hiroshi; Percherancier, Yann; Ruffié, Gilles; Dufour, Philippe; Veyret, Bernard; Lagroye, Isabelle


    In recent decades, concern has been growing about decreasing fecundity and fertility in the human population. Exposure to non-ionizing electromagnetic fields (EMF), especially radiofrequency (RF) fields used in wireless communications has been suggested as a potential risk factor. For the first time, we evaluated the effects of exposure to the 2450MHz Wi-Fi signal (1h/day, 6days/week) on the reproductive system of male and female Wistar rats, pre-exposed to Wi-Fi during sexual maturation. Exposure lasted 3 weeks (males) or 2 weeks (females), then animals were mated and couples exposed for 3 more weeks. On the day before delivery, the fetuses were observed for lethality, abnormalities, and clinical signs. In our experiment, no deleterious effects of Wi-Fi exposure on rat male and female reproductive organs and fertility were observed for 1h per days. No macroscopic abnormalities in fetuses were noted, even at the critical level of 4W/kg. Copyright © 2012 Elsevier Inc. All rights reserved.

  12. Sperm DNA damage has a negative effect on early embryonic development following in vitro fertilization

    Directory of Open Access Journals (Sweden)

    Wei-Wei Zheng


    Full Text Available Sperm DNA damage is recognized as an important biomarker of male infertility. To investigate this, sperm DNA damage was assessed by the sperm chromatin dispersion (SCD test in semen and motile spermatozoa harvested by combined density gradient centrifugation (DGC and swim-up in 161 couples undergoing in vitro fertilization (IVF. Semen analysis and sperm DNA damage results were compared between couples who did or did not achieve pregnancy. The sperm DNA damage level was significantly different between the two groups (P < 0.05 and was negatively correlated with IVF outcomes. Logistic regression analysis confirmed that it was an independent predictor for achieving clinical pregnancy. The effects of different levels of sperm DNA damage on IVF outcomes were also compared. There were significant differences in day 3 embryo quality, blastocyst formation rate, and implantation and pregnancy rates (P < 0.05, but not in the basic fertilization rate between the two groups. Thus, sperm DNA damage as measured by the SCD appears useful for predicting the clinical pregnancy rate following IVF.

  13. Low temperatures are required to induce the development of fertile flowers in transgenic male and female early flowering poplar (Populus tremula L.). (United States)

    Hoenicka, Hans; Lehnhardt, Denise; Briones, Valentina; Nilsson, Ove; Fladung, Matthias


    Until now, artificial early flowering poplar systems have mostly led to the development of sterile flowers. In this study, several strategies aimed at inducting fertile flowers in pHSP::AtFT transgenic poplar were evaluated, in particular the influence of temperature and photoperiod. Our results provide evidence that temperature, and not photoperiod, is the key factor required for the development of fertile flowers in early flowering poplar. Fertile flowers were only obtained when a cold treatment phase of several weeks was used after the heat treatment phase. Heat treatments induced AtFT gene activity through activation of the heat-shock promoter (pHSP). Photoperiod did not show a similar influence on flower fertility as pollen grains were obtained under both long- and short-day conditions. Fertility was confirmed in flowers of both male and female plants. For the first time, crosses were successfully performed with transgenic female early flowering poplar. All mature flowers obtained after 8 weeks of inductive treatments were fertile. Gene expression studies also confirmed that cold temperatures influenced expression of poplar genes homologous to 'pollen development genes' from Arabidopsis thaliana (L.) Heynh. Homology and expression patterns suggested a role for PtTDF1, PtBAM1, PtSERK1/2 and PtMS1 on anther and pollen development in poplar flowers. The system developed in this study allows a fast and very reliable induction of fertile poplar flowers in a very short period of time. The non-reproductive phase, usually 7-10 years, can now be shortened to 6-10 months, and fertile flowers can be obtained independently of the season. This system is a reliable tool for breeding purposes (high-speed breeding technology), genomics and biosafety research. © The Author 2016. Published by Oxford University Press. All rights reserved. For Permissions, please email:

  14. Evaluating the Role of First Polar Body Morphology on Rates of Fertilization and Embryo Development in ICSI Cycles

    Directory of Open Access Journals (Sweden)

    Iman Halvaei


    Full Text Available Background: Recent studies have demonstrated that morphology of the first polar body (1st PBis related to oocyte viability, which can be used as a prognostic tool to predict oocyte performanceand pregnancy outcomes in an intracytoplasmic sperm injection (ICSI program. According to somestudies, there is a correlation between oocyte performance and 1st PB morphology, while others havenot reported any correlation. The objective of this study is to evaluate the role of 1st PB morphologyon rates of fertilization and embryo development in ICSI cases.Materials and Methods: In this prospective study morphological characteristics of 470 metaphaseII (MII oocytes were assessed in 80 ICSI cycles. The women were ages 21-42 years (mean 32.6 ±0.2. Their oocytes were retrieved after a hyperstimulation protocol. After denudation, all oocyteswere evaluated for 1st PB morphology. The oocytes were divided into two groups of A (normal 1stPB and B (abnormal fragmented 1st PB. In addition, other abnormalities, such as refractile bodies(RF, wide previtelline space (wPVS, central and general granulation, bull’s eye, vacuole, smoothendoplasmic reticulum cluster (SERc, debris in PVS, shape and dark oocyte were checked. Forverifying of fertilization, about 18-19 hours post-ICSI, oocytes were checked for two-pronuclear.Assessments of embryo quality, development and embryo transfer were done at day two. Chisquare,Fisher’s exact and independent sample t tests were chosen for statistical analysis.Results: Twenty-seven percent of oocytes had fragmented 1st PB, while the remainder was associatedwith other morphological abnormalities. A total of 46.1% and 26.9% of oocytes showed double andmultiple defects, respectively. RF was the most common abnormality observed in group B. Nosignificant differences in women’s’ ages between groups A and B were noted (p=0.3. A total of 179and 107 oocytes (61.5% vs. 59.8% were fertilized in groups A and B, respectively (p=0.7. Therates of

  15. Impaired fertility in African-American women: an investigation of behavioral risks. (United States)

    Kelly-Weeder, Susan


    African-American women are disproportionately affected by impaired fertility. The literature reflects a number of potential behavioral risks associated with fertility impairment. However, few researchers have investigated these risks in African-American women. The purpose of this study was to explore the relationship between behavioral factors and impaired fertility in African-American women. A secondary analysis of data was employed from the 2002 National Survey of Family Growth (NSFG) and multiple logistic regression techniques were used to develop an explanatory model of impaired fertility in a sample of 364 African-American women of childbearing age. Findings from this current study suggested that factors directly related to impaired fertility included increasing age, current smoking, self-reported health status, and a history of gynecologic problems. Protective effects were associated with previous condom use. Using the knowledge of behavioral threats to fertility, women's health-care providers can screen and assist women in modifying their fertility risks.

  16. Idaho National Laboratory Research & Development Impacts

    Energy Technology Data Exchange (ETDEWEB)

    Stricker, Nicole [Idaho National Lab. (INL), Idaho Falls, ID (United States)


    Technological advances that drive economic growth require both public and private investment. The U.S. Department of Energy’s national laboratories play a crucial role by conducting the type of research, testing and evaluation that is beyond the scope of regulators, academia or industry. Examples of such work from the past year can be found in these pages. Idaho National Laboratory’s engineering and applied science expertise helps deploy new technologies for nuclear energy, national security and new energy resources. Unique infrastructure, nuclear material inventory and vast expertise converge at INL, the nation’s nuclear energy laboratory. Productive partnerships with academia, industry and government agencies deliver high-impact outcomes. This edition of INL’s Impacts magazine highlights national and regional leadership efforts, growing capabilities, notable collaborations, and technology innovations. Please take a few minutes to learn more about the critical resources and transformative research at one of the nation’s premier applied science laboratories.

  17. Liberia: National Security Interests in Transformational Development

    National Research Council Canada - National Science Library

    Coleman, Carolyn I


    Liberia is of national security interest to the United States of America. Liberia's 14-year civil war ended in 2003, leaving the country with a collapsed government and failing economic, physical, and social infrastructures...

  18. Low frequency electric and magnetic fields - effect on fertility and fetal development

    International Nuclear Information System (INIS)

    Thommesen, G.


    The epidemiological as well as the experimental data are still inconclusive. Inconsistencies within and between research reports make it impossible to state whether, or under what circumstances, low frequency fields may be harmful to reproduction by reducing fertility or by causing fetal malformations or death. The data indicate, however, that a certain care should be exercised in the case of NMR diagnostic imaging, industrial magnetic field exposure, and paramedical pulsed magnetic field therapy on women who might be expected to be in the first trimester of pregnancy, particularly in the unindentified initial phase. Work in connection with visual display units, living in the neighbourhood of overhead high-voltage powerlines, or other every-day sources of exposure to low frequency fields seem, however, to be an insignificant or non-existent threat to an unborn life. 147 refs

  19. Effect of selenium on the development of selected indicators of fertility in dairy cows

    Directory of Open Access Journals (Sweden)

    A. Balicka-Ramisz


    Full Text Available Aim: The aim of this study was to determine selenium (Se concentration in the blood serum of dairy cows and to establish its influence on the level of production and reproduction traits. Materials and Methods: The study was performed on the farm located in Western Pomerania - Poland and involved 120 cows, which were selected using the analog method on the basis of their physiological state, lactation number, milk yield, age, and genotype. The following indices were analyzed in individual groups: Calving interval, gestation interval, insemination index, standstill of placenta. Se concentration in the blood serum was determined with the spectrofluorometric method. Results: The mean serum Se concentration was in cows 0.038 μg/ml. The use of Se preparations has raised fertility, which was documented statistically. Conclusion: The study revealed that the problem of Se deficiency is still present in some dairy cattle herds in Western Pomerania - Poland.

  20. Assessment of Fertility Status in the Male Sumatran Rhino at the Sumateran Rhino Sanctuary, Way Kambas National Park, Lampung

    Directory of Open Access Journals (Sweden)



    Full Text Available Sumatran rhino is the most endangered rhino species. Its population is estimated less than 300 individuals remaining in the wild with highly declining rate to 50% in the last 15 years. The number of male rhinoceroses in the captivity are very few, therefore the assessment of its fertility is very important in order to support the breeding success since the captive breeding success is very poor. The objectives of this study were (i to determine the male reproductive status, (ii to establish a reliable semen collection method, and (iii to assess semen parameters of the fresh collected sample. Three methods of semen collection were examined to determine its fertilizing potential, i.e. (i stimulated combination of artificial vagina (AV, penile massage (PM and accessory gland massage (AGM; (ii AV and PM; and (iii only with PM. The first method gave the best result with an ejaculation success of 85.71% (6/7, n = 7. The second and third methods obtained an ejaculation success rate of 50% (2/4, n = 4 and 25% (1/4, n = 4, respectively. The collected ejaculates had a volume of 1.2-12.4 ml with whitish to cream turbid colour and pH 6.90-6.99. Sperm concentration was (143-333 × 103 sperm/ml. The quality of the sperm was low with only approximately 1% of them moved forward slowly. Approximately 80% of the spermatozoa were immature (prox. cytoplasmic droplet with head (macro-, microcephalic and tail abnormalities (broken tail. Semen quality increased after several collections and the amount of immature sperm decreased up to 5%. Electroejaculation procedure could produce 34 ml semen, but no sperm was found in the ejaculate. Hence, the combination of AV, PM, and AGM could get higher volume of ejaculate compared to other methods, but sperm concentration was better obtained using AV and PM only. Repeated semen collection increased semen quality, although the male has low fertilizing capacity due to low sperm concentration (oligozoospermia and small volume of the

  1. National Stormwater Calculator: Low Impact Development Stormwater Control Cost Estimation (United States)

    Stormwater discharges continue to cause impairment of our Nation’s waterbodies. EPA has developed the National Stormwater Calculator (SWC) to help support local, state, and national stormwater management objectives to reduce runoff through infiltration and retention using green i...

  2. Effects of date palm pollen on fertility and development of reproductive system in female Balb/C mice

    Directory of Open Access Journals (Sweden)

    Moshfegh Fazeleh


    Full Text Available Introduction: The Phoenix dactylifera or date palm pollen (DPP is widely used for male infertilityin traditional medicine. The aim of this study was to evaluate the effect of DPP on fertility and development of female reproductive system in Balb/C mice.Methods: Ten groups were assigned to 2 control and 8 experimental groups. On the control groups1 and 2 no treatment was conducted, but in the control group 2, after 10 days the mice were mated.In experimental groups 1 and 2, the animals received DPP (100 and 200 mg/kg, respectively byoral administration for 10 days. In experimental groups 3 and 4 percentage of mating was evaluatedafter 10 days. Experimental groups 5 and 6 received DPP during gestation. Embryos were removedto evaluate ovaries histology. For experimental groups 7 and 8, DPP was administered until 21thday after birth. The offspring ovaries were removed to evaluate histological parameters. The levelsof sexual hormones were also measured.Results: Several parameters of ovaries in offspring, including mass index, diameter of ovaries,number of primary and secondary graph follicles and corpora luteal, percentage of mating, bodymass index and Crown rump (CR of embryos, diameter of ovary, basic sexual cell number inembryos, and mass index increased in experimental groups in comparison to the controls.However, luteinizing hormone (LH and follicle-stimulating hormone (FSH in the experimentalgroups were not significantly different from those in control groups (P > 0.05, while estrogen andprogesterone considerably increased in experimental groups (P < 0.05.Conclusion: Results of our investigation propose that DPP can create an appropriate situationfor oogenesis and maintain efficient fertility in female mice which it may be considered as usefulnutraceuticals for potentiation of fertility in future human studies.

  3. Situation and development of worldwide agri-environment: Agricultural land uses, fertilizers consumption and carbon dioxide equivalent emissions

    Directory of Open Access Journals (Sweden)

    WenJun Zhang


    Full Text Available Based on FAO data on agri-environment worldwide, we choose ten major countries to analyse agrienvironment situation and development worldwide. The results showed that China has the greatest agricultural area, seconded by Australia and USA, and third by Brazil and India. USA is the largest country in arable land area, seconded by India, and third by China. Since earlier 1990s, China has become the largest country in the area of permanent crops, seconded by India. Brazil is the largest country in the annual growth of arable land area, seconded by China, and third by Australia. In the area of permanent meadows and pastures, China grows mostly and seconded by Brazil and third by India. India has the largest harvested area, closely seconded by China, and third by USA. Australia is the most fast growing country in area harvested, seconded by Brazil and third by India. China and India are the two countries with most emissions of agricultural CO2 and equivalents, seconded by Brazil, and third by USA. China grows mostly in emissions of agricultural CO2 and equivalents, seconded by Brazil and India, and followed by Canada and USA. China is the largest country of fertilizers consumption, seconded by India, and third by USA and Brazil. China grows mostly in P and K fertilizers consumption. India holds the No. 1 position in the annual growth of N consumption. In general, China and India have the largest amount of emissions of agricultural CO2 and equivalents and fertilizers consumption. Annual growths of arable land area and permanent meadows and pastures of China are also the highest. Agri-environment of China, India, and Brazil has deteriorated significantly. Agri-environment of Australia seems to be deteriorated in the past years. Agri-environment of European countries is relatively optimistic.

  4. On the pace of fertility decline in sub-Saharan Africa

    Directory of Open Access Journals (Sweden)

    David Shapiro


    Full Text Available Background: This descriptive finding examines the comparative pace of fertility decline in sub-Saharan Africa, relative to Asia, Latin America and the Caribbean, and Northern Africa. Objective: We seek to determine if fertility decline has been slower in sub-Saharan Africa than elsewhere in the developing world. Methods: United Nations 2017 estimates of national fertility are used in assessing the comparative pace of fertility decline, and the four regions are compared in terms of how far they are into their fertility transition. Results: The data shows clearly that fertility decline in sub-Saharan Africa, still at a comparatively early stage, has been considerably slower than the earlier declines in Asia, Latin America and the Caribbean, and Northern Africa at comparable stages of the transition, and displays less within-region heterogeneity than the transitions in these other regions. Conclusions: The slower pace of fertility decline in sub-Saharan Africa, in conjunction with the high current fertility levels in the region, means that in the absence of policies seeking to accelerate fertility decline, sub-Saharan Africa will continue to experience rapid population growth that in turn will constrain its development. Contribution: Presentation of data in a novel way (Figures 2‒4, and associated calculations unambiguously demonstrates the slow pace of fertility decline in sub-Saharan Africa compared with other regions of the world.

  5. Family size, fertility preferences, and sex ratio in China in the era of the one child family policy: results from national family planning and reproductive health survey. (United States)

    Ding, Qu Jian; Hesketh, Therese


    To examine the impact of the one child family policy in China on fertility, preferred family size, and sex ratio. Secondary analysis of data from the Chinese cross sectional national family planning and reproductive health survey, 2001. Interviews of representative sample of women aged 15-49. Data were obtained from 39,585 women, with a total of 73,202 pregnancies and 56,830 live births. The average fertility rate in women over 35 (n = 17,078) was 1.94 (2.1 in rural areas and 1.4 in urban areas) and for women under 35 (n = 11,543) 1.73 (1.25 and 1.79). Smaller families were associated with younger age, higher level of education, and living in an urban area. The male to female ratio was 1.15 and rose from 1.11 in 1980-9 to 1.23 for 1996-2001. Most women wanted small families: 35% preferred one child and 57% preferred two. Since the one child family policy began, the total birth rate and preferred family size have decreased, and a gross imbalance in the sex ratio has emerged.

  6. Bariatric Surgery in Obese Women of Reproductive Age Improves Conditions That Underlie Fertility and Pregnancy Outcomes: Retrospective Cohort Study of UK National Bariatric Surgery Registry (NBSR). (United States)

    Edison, Eric; Whyte, Martin; van Vlymen, Jeremy; Jones, Simon; Gatenby, Piers; de Lusignan, Simon; Shawe, Jill


    The aims of this study are the following: to describe the female population of reproductive age having bariatric surgery in the UK, to assess the age and ethnicity of women accessing surgery, and to assess the effect of bariatric surgery on factors that underlie fertility and pregnancy outcomes. Demographic details, comorbidities, and operative type of women aged 18-45 years were extracted from the National Bariatric Surgery Registry (NBSR). A comparison was made with non-operative cases (aged 18-45 and BMI ≥40 kg/m 2 ) from the Health Survey for England (HSE, 2007-2013). Analyses were performed using "R" software. Data were extracted on 15,222 women from NBSR and 1073 from HSE. Women aged 18-45 comprised 53 % of operations. Non-Caucasians were under-represented in NBSR compared to HSE (10 vs 16 % respectively, p fertility and pregnancy outcomes. A prospective study is required to verify these effects.

  7. Effects of 17beta-estradiol, and its metabolite, 4-hydroxyestradiol on fertilization, embryo development and oxidative DNA damage in sand dollar (Dendraster excentricus) sperm. (United States)

    Rempel, Mary Ann; Hester, Brian; Deharo, Hector; Hong, Haizheng; Wang, Yinsheng; Schlenk, Daniel


    Oxidative compounds have been demonstrated to decrease the fertilization capability and viability of offspring of treated spermatozoa. As estrogen and its hydroxylated metabolites readily undergo redox cycling, this study was undertaken to determine if estrogens and other oxidants could damage DNA and impair sperm function. Sperm was preexposed to either 17beta-estradiol (E2), 4-hydroxyestradiol (4OHE2) or the oxidant t-butyl hydroperoxide (t-BOOH), and allowed to fertilize untreated eggs. The fertilization rates and development of the larvae were assessed, as well as the amount of 8-oxodeoxyguanosine (8-oxodG) as an indication of oxidative DNA damage. All compounds caused significant decreases in fertilization and increases in pathological abnormalities in offspring, with 4OHE2 being the most toxic. Treatment with 4OHE2 caused a significant increase of 8-oxodG, but E2 failed to show any effect. Pathological abnormalities were significantly correlated (r(2)=0.44, p< or =0.05) with 8-oxodG levels in sperm treated with t-BOOH and 4OHE2, but not E2. 8-OxodG levels also were somewhat weakly correlated with impaired fertilization in 4OHE2-treated sperm (r(2)=0.33, p< or =0.05). The results indicate that biotransformation of E2 to 4OHE2 enhances oxidative damage of DNA in sperm, which can reduce fertilization and impair embryonic development, but other mechanisms of action may also contribute to these effects.

  8. Heat stress remediation of rice (Oryza sativa L. growth and development, and nutrients uptake through fertilizers management in tropics

    Directory of Open Access Journals (Sweden)

    Mohammad Taghi Karbalaei Aghamolki


    Full Text Available Increased evidences have shown that agricultural crop production to be constrained by heat stress that can significantly reduce crop growth and development as well as nutrients uptake. Nitrogen and potassium are two macro-essential nutrients that influence a number of biochemical and physiological processes that involve in crop production, and also contribute to the survival of crop exposed to high temperature tension. Therefore, the current glasshouse experiment was conducted to explore the effect of nitrogen and potassium fertilizers application on the resistance of rice against heat stress. The highest decrease in morphological and physiological characteristics were observed in aborted spikelets per panicle about 2 time, chlorophyll content by 4.23% and plant height by 2.43% over control, meanwhile the fertile spikelets per panicle by 38.5%, grain yield by 25.25%, the numbers of tillers per hill by 10.76% and effective tillers per hill by 9.1% decreased in heat stress pots. In case of macronutrients uptake, the highest decreased in N uptake was observed in straw by 12.45% and followed by total (12.21% and grain (11.68%, meanwhile K uptake was decrease in order of grain(28.96%> total (18.26%>straw (13.43% (P<0.05. The highest rate of single N application in both sources remediated the morphological characters between 15 to 63%, meanwhile the single K application increased them about 2%. Also, the fertilizers management remediated the negative effect of heat stress in order of: yield (<2 times, fertile spikelets (< 2 times, effective tillers (57.6% and 1000 grains weight (about 4% compare to control in applied heat treatments. With respect to single application of N and K that increased the N and K uptake (grain, total and straw averagely about 2.2 and 1.2 times more than control at heat stress pots, respectively, the highest levels of urea and applied K, increased all uptake parameters averagely about 2-3 times.

  9. Developing the information management system for safeguards national inspection

    Energy Technology Data Exchange (ETDEWEB)

    Park, S. J.; Jeon, I.; Park, W. S.; Min, K. S. [KAERI, Taejon (Korea, Republic of)


    The inspection information management system for safeguards national inspection is aimed to do the national safeguards inspection with efficiency, and to decrease the inspector's load to write inspection report by systematizing the inspection jobs and sharing the inspection data. National safeguards inspection is consisted two large jobs. The first is the national safeguards supporting job of managing to support the national inspection mission. The other is the writing a national inspection report after completing the national inspection. Before the developing of inspection information management system, the official tools(spread sheet, word processor) are usually used. But there is problem to share the data, to produce the statistics data. To solve the these problem, we developed the inspection information management system that process the job from initial to final inspection work, and opened user education. This paper explain the procedure of developing the inspection information management system for safeguards national inspection.

  10. Developing the information management system for safeguards national inspection

    International Nuclear Information System (INIS)

    Park, S. J.; Jeon, I.; Park, W. S.; Min, K. S.


    The inspection information management system for safeguards national inspection is aimed to do the national safeguards inspection with efficiency, and to decrease the inspector's load to write inspection report by systematizing the inspection jobs and sharing the inspection data. National safeguards inspection is consisted two large jobs. The first is the national safeguards supporting job of managing to support the national inspection mission. The other is the writing a national inspection report after completing the national inspection. Before the developing of inspection information management system, the official tools(spread sheet, word processor) are usually used. But there is problem to share the data, to produce the statistics data. To solve the these problem, we developed the inspection information management system that process the job from initial to final inspection work, and opened user education. This paper explain the procedure of developing the inspection information management system for safeguards national inspection

  11. Education and National Development in Nigeria: A Philosophical ...

    African Journals Online (AJOL)

    The paper examines the key words: culture and development, and in the process attempts to bring out their relationship to education in a developing country like Nigeria. It further states that investment in education is sine-qua-non with national development. Hence this paper sees education as an important tool for national ...

  12. Education, Democracy and National Development: The Way Forward

    African Journals Online (AJOL)

    This paper examines the present state of Education, Democracy and National Development in the present Democratic dispensation in Nigeria. It proposes a number of steps for improving and reinforcing the foundations of our educational systems for a sustainable national development. A major tool of development is ...

  13. Consequences of different dietary energy sources during follicular development on subsequent fertility of cyclic gilts. (United States)

    Almeida, F R C L; Machado, G S; Borges, A L C C; Rosa, B O; Fontes, D O


    The objective of the present study was to investigate the effects of dietary-induced insulin enhancement during the late luteal phase on subsequent fertility of gilts. Fifty-two littermate cyclic gilts were subjected to dietary treatments where two energy sources were tested: corn starch (T1) and soybean oil (T2). The experimental diets were supposed to provide similar amounts of dietary energy, but from different sources. Gilts were fed ad libitum, starting day 8 of the estrous cycle, until the next standing heat. Blood sampling was performed in a subgroup of 20 gilts on days 14 and 21 of the cycle for analyses of glucose and insulin, and after ovulation detection until 18 h after ovulation for progesterone. All gilts were slaughtered on day 28 of pregnancy and the reproductive tracts recovered for further analysis. T1 gilts showed higher postprandial insulin peak on days 14 and 21 and lower glucose levels 4 h after feeding on day 14 (Pgilts showed higher ovulation rates, number of embryos, embryo weight and placental weight (Pgilts and, thus, improve reproductive efficiency when feeding starch as the main energy source during the late luteal and follicular phases of the cycle.

  14. National forests on the edge: development pressures on America's national forests and grasslands. (United States)

    Ralph J. Alig; Eric M. White; Sara J. Comas; Mary Carr; Mike Eley; Kelly Elverum; Mike O' Donnell; David M. Theobald; Ken Cordell; Jonathan Haber; Theodore W. Beauvais


    Many of America’s national forests and grasslands—collectively called the National Forest System—face increased risks and alterations from escalating housing development on private rural lands along their boundaries. National forests and grasslands provide critical social, ecological, and economic benefits to the American public. This study projects future housing...

  15. Global Trends in Adolescent Fertility, 1990-2012, in Relation to National Wealth, Income Inequalities, and Educational Expenditures. (United States)

    Santelli, John S; Song, Xiaoyu; Garbers, Samantha; Sharma, Vinit; Viner, Russell M


    National wealth, income inequalities, and expenditures on education can profoundly influence the health of a nation's women, children, and adolescents. We explored the association of trends in national socioeconomic status (SES) indicators with trends in adolescent birth rates (ABRs), by nation and region. An ecologic research design was employed using national-level data from the World Bank on birth rates per 1,000 women aged 15-19 years, national wealth (per capita gross domestic product or GDP), income inequality (Gini index), and expenditures on education as a percentage of GDP (EduExp). Data were available for 142 countries and seven regions for 1990-2012. Multiple linear regression for repeated measures with generalized estimating equations was used to examine independent associations. ABRs in 2012 varied >200-fold-with the highest rates in Sub-Saharan Africa and lowest rates in the Western Europe/Central Asia region. The median national ABR fell 40% from 72.4/1,000 in 1990 to 43.6/1,000 in 2012. The largest regional declines in ABR occurred in South Asia (70%), Europe/Central Asia (63%), and the Middle East/North Africa (53%)-regions with lower income inequality. In multivariable analyses considering change over time, ABRs were negatively associated with GDP and EduExp and positively associated with greater income inequality. ABRs have declined globally since 1990. Declines closely followed rising socioeconomic status and were greater where income inequalities were lower in 1990. Reducing poverty and income inequalities and increasing investments in education should be essential components of national policies to prevent adolescent childbearing. Copyright © 2016 Society for Adolescent Health and Medicine. Published by Elsevier Inc. All rights reserved.

  16. Infertility, infertility treatment and psychomotor development: the Danish National Birth Cohort. (United States)

    Zhu, Jin Liang; Basso, Olga; Obel, Carsten; Hvidtjørn, Dorte; Olsen, Jørn


    Babies born of infertile couples, regardless of treatment, have a higher risk of preterm birth and low birthweight, conditions associated with delayed development. We examined developmental milestones in singletons as a function of parental infertility [time to pregnancy (TTP) > 12 months] and infertility treatment. From the Danish National Birth Cohort (1997-2003), we identified 37 897 singletons born of fertile couples (TTP 12 months), and 3309 born after infertility treatment. When the children were about 18 months old, mothers reported 12 developmental milestones by responding to structured questions. We defined a failure to achieve the assessed milestone or the minimal numbers of milestones in a summary (motor, or cognitive/language skills) as delay. Naturally conceived children born of infertile couples had a pattern of psychomotor development similar to that of children born of fertile couples, but increasing TTP correlated with a modest delay. When the analysis was restricted to infertile couples (treated and untreated), children born after treatment showed a slight delay in cognitive/language development (odds ratio 1.24, [95% confidence interval 1.01, 1.53]) for not meeting at least three out of six cognitive/language milestones); children born after intracytoplasmic sperm injection (ICSI) had the highest estimated relative risk of delay for most milestones, especially motor milestones. These results suggest that a long TTP may be associated with a modest developmental delay. Infertility treatment, especially ICSI, may be associated with a slight delay for some of these early milestones.

  17. Effect of fertilizer prepared from human feces and straw on germination, growth and development of wheat (United States)

    Liu, Dianlei; Xie, Beizhen; Dong, Chen; Liu, Guanghui; Hu, Dawei; Qin, Youcai; Li, Hongyan; Liu, Hong


    Solid waste treatment is one of the most important rate-limiting steps in the material circulation and energy flow of Bioregenerative Life Support System (BLSS). In our previous work, an efficient and controllable solid waste bio-convertor has been built and a solid waste degradation efficiency of 41.0% has been reached during a 105-d BLSS experiment. However, the fermented residues should be further utilized to fulfill the closure of the system. One solution might be to use the residues as the fertilizer for plant cultivation. Thus in this study, substrates were prepared using different ratios of the fermented residues to the vermiculite. And the influences of different ratios of the fermented residues on the seed germination, growth, photosynthetic characteristics and antioxidant capacity of wheat were studied. The results showed that the optimal rate of the fermented residue was 5%. With this ratio, the seed germination reached 97.3% with the root length, shoot length and biomass production as 59 mm, 52 mm and 150 mg, respectively, at the 4th day. Besides, the highest straw height of 25.1 cm was obtained at the 21st day. The salinity adversely affected the growth and some relevant metabolic processes of wheat. The Group-40% led to the lowest seed germination of 34.7% and the minimum straw height of 15 cm. This inhibition might be caused by the high Na content of 2118 mg/kg in the fermented residues. Chlorophyll b was more sensitive to the mineral nutrition stress and affects the wheat photosynthetic characteristics. Higher reactive oxygen species levels and reduced antioxidant enzymes may contribute, directly and/or indirectly, to the decline in the observed pigment contents in wheat.

  18. Research and development in pilot plant production of granular NPK fertilizer (United States)

    Failaka, Muhamad Fariz; Firdausi, Nadia Zahrotul; Chairunnisa, Altway, Ali


    PT Pupuk Kaltim (Pupuk Kaltim) as one of the biggest fertilizer manufacturer in Indonesia, always striving to improve the product quality and achieve the optimal performance while facing the challenges of global competition NPK (Nitrogen, Phosphorus, Potassium) market. In order to continuously improve operations and processes of two units NPK compound plant, Pupuk Kaltim has successfully initiated a new facility which is referred to as a NPK pilot-scale research facility with design capacity of 30 kg/hr. This mini-plant is used to assist in the scale up of new innovations from laboratory research to better understand the effect of using new raw materials and experiment with process changes to improve quality and efficiency. The pilot installation is composed of the following main parts: mixer, screw feeder, granulator, dryer and cooler. The granulator is the equipment where NPK granules is formed by spraying appropriate steam and water onto raw materials in a rotating drum. The rotary dryer and cooler are intended for the drying process where temperature reduction and the final moisture are obtained. As a part of innovations project since 2014, the pilot plant has conducted many of experiments such as trials using Ammonium Sulfate (ZA) as a new raw material, alternative raw materials of Diammonium Phosphate (DAP), Potassium Chloride (KCl) and clay, and using a novel material of fly ash. In addition, the process engineering staff also conduct the trials of raw materials ratio so that an ideal formulation with lower cost can be obtained especially when it is applied in the existing full-scale plant.

  19. Reconstructing historical fertility change in Mongolia: Impressive fertility rise before continued fertility decline

    Directory of Open Access Journals (Sweden)

    Thomas Spoorenberg


    Full Text Available Background: To date, historical fertility change in Mongolia has been analyzed starting from the 1960s. It is generally accepted that the adoption of pro-natalist policies resulted in very high fertility levels during the 1960s and 1970s and that their relaxation in the mid-1970s contributed to the onset of fertility decline. Objective: The objective of this paper is to reconstruct fertility levels and trends in Mongolia before the 1960s in order to offer an alternative view of the historical fertility change in the country. Methods: Mobilizing a large set of data from different sources and applying diverse estimation techniques, a consistent reconstruction of nearly a century of fertility change in Mongolia is conducted. For the first time, fertility estimates before 1960 are introduced. The quality of these estimates is assessed through cross-comparison and prospective reconstruction of the country's population. Results: The different fertility estimates give a very consistent picture of historical fertility change in Mongolia, indicating that total fertility stagnated until the late 1940s and then increased by about 2.5 children per woman within 15 years. The population of Mongolia can be consistently reproduced assuming almost constant fertility between 1918 and 1956. Conclusions: The improvement in health and living standards related to the establishment of a socialist society is the main factor explaining the variations in fertility before the 1960s in Mongolia. This study reinstates the importance of social and economic development in explaining fertility change in the country. Comments: This study calls for demographers to reconstruct long-term population development in statistically less-developed countries to better understand the global process of fertility transition.

  20. Effect of mercuric chloride on fertilization and larval development in the River Frog, Rana heckscheri (Wright) (Anura: Ranidae)

    Energy Technology Data Exchange (ETDEWEB)

    Punzo, F. (Univ. of Tampa, FL (United States))


    Previous investigations have indicated that heavy metals such as copper, cadmium, lead and mercury can act as systemic toxicants in many species of wildlife. Although numerous studies have emphasized the effects of metals and pesticides on metabolism, growth, survivorship, neural processes and reproduction in a number of taxa, little information is available on the effects of sublethal concentrations of metals on the reproductive physiology of amphibians. Industrial processes and mining activities can release substantial concentrations of heavy metals such as mercury into aquatic habitats. Since most amphibians have obligate aquatic larval stages, they are exposed to pollutants discharged into the aquatic environment. Amphibians can act as accumulators of heavy metals and their larval stages are useful indicators of pollution levels in the field. What little data are available, indicate that metals can significantly reduce viability in amphibians through their actions on metabolism, development and gametogenesis. The recent concerns over worldwide declines in amphibian populations and the susceptibility of amphibian populations to environmental toxicants, led me to assess the effect of mercuric chloride, one of the most common and persistent toxicants in aquatic environments, on fertilization and larval development in the river frog, Rana heckscheri (Wright). Although there is some information on fish, very little data are available on the effects of mercury on fertilization in amphibians generally, and no published data exist for R. heckscheri. This species is a conspicuous component of the aquatic fauna of parts of the southeastern United States where mercury levels have increased significantly over the last two decades. 22 refs., 2 tabs.

  1. Philosophy, Human Development and National Question | Ekei ...

    African Journals Online (AJOL)

    While the solution to this dilemma is still being sought, Socrates shifted the attention of philosophy (with obvious reasons) from nature to ethical-political question, that is, to the issue of human development. It interests this essay, to find out, what exactly is human development, and why philosophy after Socrates considers ...

  2. Contextualising the National Development Plan for enhanced ...

    African Journals Online (AJOL)

    Strategy, Integrated Development Planning, enhanced service delivery ..... Regarding transport and logistics infrastructure, the key focus .... In essence, spatial equity aims to locate services at accessible and convenient places for residents and support through well-developed transport systems. Therefore, the. NDP refers to ...

  3. Linear accelerator development at Brookhaven National Laboratory

    International Nuclear Information System (INIS)

    Batchelor, K.


    A description is given of operating experience on the 200 MeV Proton Injector Linace of the A.G.S. emphasizing developments in field phase and amplitude control and beam diagnostics. Developments in auxilliary use of the machine are also described

  4. T Policy with the National Sustainable Development Strategy in Sri ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Aligning the National S&T Policy with the National Sustainable Development Strategy in Sri Lanka. Sri Lanka does not have an official science and technology (S&T) policy. Investments in S&T have so far occurred on an ad-hoc basis. Nevertheless, government and research and development (R&D) institutions have ...

  5. Rural Women Empowerment: A Panacea For National Development ...

    African Journals Online (AJOL)

    This paper examines the role of women in the process of national development. Because a large number of them live in the rural areas, it is the view that qualitative national development which is human-centered cannot be complete if a part of those who should sum up to make a total (rural women) are neither recognised, ...

  6. Developing National Systems of Innovation: University-Industry ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    30 janv. 2015 ... Developing National Systems of Innovation: University-Industry Interactions in the Global South. Book cover Developing ... of Campinas, Brazil. Glenda Kruss is research director at the Human Sciences Research Council, South Africa. Keun Lee is professor at Seoul National University, South Korea.

  7. [Education, modernity, and fertility in Costa Rica]. (United States)

    Stycos, J M


    In an effort to identify the causal mechanisms involved in the relationship between education and fertility in Costa Rica, all married women who were interviewed in the National Fertility Survey were reinterviewed in 1977-78. Questions on modernity and attitudes toward family size were designed to measure the extent of their influence on fertility. Questions on modernity were grouped into 4 measures of mass communications/information, sex roles, husband's power, and "instrumental activism." The intercorrelation of the 4 measures was enough to justify their use as separate subscales but high enough to permit their combined use as a single measure of modernity. The correlation between the combined total and education was strong and positive at .68, while the correlation between education and the number of live births controlled for age was -.35. Results of a multiple regression analysis indicate that high levels of general information and exposure to mass media are responsible for the positive correlation between education and fertility. A variety of scales were developed to measure the extent to which predispositions toward family size, numerical preference, and desire for additional children were responsible for the relationship between general information and fertility. Modernity and education showed strong negative relationships to predisposition toward family size, moderate negative relationships to size preference, and almost no relationship to the desire for more children.

  8. The Impact of Soil Sampling Errors on Variable Rate Fertilization

    Energy Technology Data Exchange (ETDEWEB)

    R. L. Hoskinson; R C. Rope; L G. Blackwood; R D. Lee; R K. Fink


    Variable rate fertilization of an agricultural field is done taking into account spatial variability in the soil’s characteristics. Most often, spatial variability in the soil’s fertility is the primary characteristic used to determine the differences in fertilizers applied from one point to the next. For several years the Idaho National Engineering and Environmental Laboratory (INEEL) has been developing a Decision Support System for Agriculture (DSS4Ag) to determine the economically optimum recipe of various fertilizers to apply at each site in a field, based on existing soil fertility at the site, predicted yield of the crop that would result (and a predicted harvest-time market price), and the current costs and compositions of the fertilizers to be applied. Typically, soil is sampled at selected points within a field, the soil samples are analyzed in a lab, and the lab-measured soil fertility of the point samples is used for spatial interpolation, in some statistical manner, to determine the soil fertility at all other points in the field. Then a decision tool determines the fertilizers to apply at each point. Our research was conducted to measure the impact on the variable rate fertilization recipe caused by variability in the measurement of the soil’s fertility at the sampling points. The variability could be laboratory analytical errors or errors from variation in the sample collection method. The results show that for many of the fertility parameters, laboratory measurement error variance exceeds the estimated variability of the fertility measure across grid locations. These errors resulted in DSS4Ag fertilizer recipe recommended application rates that differed by up to 138 pounds of urea per acre, with half the field differing by more than 57 pounds of urea per acre. For potash the difference in application rate was up to 895 pounds per acre and over half the field differed by more than 242 pounds of potash per acre. Urea and potash differences

  9. Development of Management Teamwork: National Overview. (United States)

    Schmuck, Richard A.

    The basis for developing vital, team-like characteristics in contemporary pluralistic America lies in the understanding and building of new interpersonal norms and skills. The new norms accept human collaboration and human diversity as basic facts for problemsolving, survival, and growth. These norms support the intent that interpersonal and…

  10. Environmental pollution-effects on national development

    International Nuclear Information System (INIS)

    Mahyuddin bin Ramli; Mohd Fadzil bin Mohd Idris


    Environmental pollution is among the major issues highlighted in many discussion between the Government and Non-Government officials whether in the developed or developing countries. The problems becoming worsen when not many people are concerned on its detrimental effects on the future generations. The increasing number of forest activities without proper replanting will also expose to flood problems, soil erosion, landslides and many more as results of environmental impacts. The urbanization process, couple with the rapid industrial development, without having proper planning and inadequate pollutions control, may also create a long term disasters. Penang island territory has been experiencing the most highly physical development growth in this country. Hence, environmental problems are becoming the major issues. This paper will discuss on the various environmental problem, particularly in Penang and possible remedials to be taken by the state and federal authority to overcome the problems. The type of pollutions such as air and water pollutions, acid rain and of course the reduction of ozone layer. Besides that the increase of heat in our climate will also be of our concern in the process of urbanization

  11. impact of cooperative societies in national development

    African Journals Online (AJOL)


    DEVELOPMENT AND THE NIGERIAN ECONOMY. ROWLAND A. ..... Nigerian economy. Put briefly, this would include the Consumers Cooperative Societies which are organized by consumers who pool their resources together in order to advance their interest in retail ... in production, profit sharing, cost-saving or risk.

  12. Empowering Nigerian youths for national economic development ...

    African Journals Online (AJOL)

    The world over, from USA to Asia, United Kingdom to Africa and Australia to Latin America, entrepreneurship has been promoted as an effective means of stimulating economic growth through the generation of greater employment opportunities, the development of local technological base and source of foreign exchange ...

  13. Fertility transition and socio-economic change in western Kenya. (United States)

    Uitto, J I


    Kenya's national survey data have shown patterns of fertility decline in the more socioeconomically advantaged regions. In the central areas, where urbanization and economic development is the highest, fertility has begun to decline rapidly. The lowest fertility was in Nairobi capital region; the Coast Province also experienced recent fertility decline. Fertility has remained high in the Western Province and in Nyanza, Rift Valley, and Eastern Provinces. The case study of Kisii district in Nyanza Province was used to illustrate the preconditions of high fertility. The district is an agriculturally rich region that includes rounded, steep-sided hills and narrow valleys. The district is a primary producer of cash crops such as coffee, tea, and pyrethrum, and other food crops including high-yielding varieties of maize. Farm size varies between 0.11 and 2.2 hectares and farms are owner occupied. All cultivable land is in use with traditional farming methods. Tractors are used in flat areas by 11.6% of farmers. 69.3% of farmers use fertilizers, but only 32% use insecticides and pesticides. Population density is 395 persons per square kilometer. The total fertility rate is 8.2 compared to 7.7 for the nation. 6% currently used contraception, and 23% have ever used. Fertility preferences of women under 25 years old is 6.9 children. Most farm labor, even among the wealthy farmers, is family labor organized by age and gender. Women are responsible for planting, weeding, harvesting and household chores. Male off-farm employment increases the agricultural production responsibilities of women. Only mothers of sons can control property and gain prestige. Modernization and land shortages have pressured families to increase nonfarm employment.

  14. Response to the National Career Development Strategy Green Paper (United States)

    Australian Journal of Career Development, 2012


    The Career Development Association of Australia (CDAA) congratulates the Commonwealth Government on the development of the National Career Development Strategy Green Paper. This is a timely and important document that provides a framework to demonstrate the central contribution that career development services play in supporting individuals,…

  15. Tracing the sustainable development of nations with integrated indicators

    NARCIS (Netherlands)

    Zoeteman, B.C.J.; Boersema, J.J.; Reijnders, L.


    Managing sustainable development as a policy issue is a complex task. The European Union Sustainable Development Strategy (CEC 2001) has stimulated EU member states to develop national sustainable development strategies. However policy makers are mostly lacking reliable and practical tools to

  16. The effect of hepatocyte growth factor on mouse oocyte in vitro maturation and subsequent fertilization and embryo development

    Directory of Open Access Journals (Sweden)

    Mohammad H. Bahadori


    Full Text Available Background: Oocyte invitro maturation is an enormously promising technology for the treatment of infertility, yet its clinical application remains limited owing to poor success rates. Therefore, this study was devised to evaluate the effect of hepatocyte growth factor (HGF on in vitro maturation of immature mouse oocytes and resulting embryos development. Materials and Method: Cumulus – oocyte complex and germinal vesicle were obtained from eighteen 6-8 weeks-old female NMRI mice 46-48 hours after administration of an injection of 5 IU PMSG (Pregnant Mares’ Serum Gonadotrophin. Oocytes were culture in TCM199 (Tissue culture medium-199 supplemented with dosages of 0, 10, 20, 50 and 100 ng/ml of HGF. After 24 hours, metaphase ІІ oocytes were co-incubated with sperms for 4-6 hours in T6 medium. Following isolation of two pronucleus embryos, cleavage of embryos was assessed in the same medium till blastocyst stage. The number of oocytes and embryos was recorded under an invert microscope and the rate of oocyte maturation, fertilization and embryos cleavage until blastocyst stage compared using of student χ2 test. Results: In all compared groups, oocytes growth and embryos development rate in the 20 ng/ml of HGF treatment group was significantly higher (p<0.05 than the control group (p<0.05.Conclusion: 20 ng/ml of HGF improved the nuclear maturation and embryo development up to blastocyst stage during culture condition

  17. The Boron Efflux Transporter ROTTEN EAR Is Required for Maize Inflorescence Development and Fertility[C][W][OPEN (United States)

    Chatterjee, Mithu; Tabi, Zara; Galli, Mary; Malcomber, Simon; Buck, Amy; Muszynski, Michael; Gallavotti, Andrea


    Although boron has a relatively low natural abundance, it is an essential plant micronutrient. Boron deficiencies cause major crop losses in several areas of the world, affecting reproduction and yield in diverse plant species. Despite the importance of boron in crop productivity, surprisingly little is known about its effects on developing reproductive organs. We isolated a maize (Zea mays) mutant, called rotten ear (rte), that shows distinct defects in vegetative and reproductive development, eventually causing widespread sterility in its inflorescences, the tassel and the ear. Positional cloning revealed that rte encodes a membrane-localized boron efflux transporter, co-orthologous to the Arabidopsis thaliana BOR1 protein. Depending on the availability of boron in the soil, rte plants show a wide range of phenotypic defects that can be fully rescued by supplementing the soil with exogenous boric acid, indicating that rte is crucial for boron transport into aerial tissues. rte is expressed in cells surrounding the xylem in both vegetative and reproductive tissues and is required for meristem activity and organ development. We show that low boron supply to the inflorescences results in widespread defects in cell and cell wall integrity, highlighting the structural importance of boron in the formation of fully fertile reproductive organs. PMID:25035400

  18. SMSNRs find favour for developing nations

    International Nuclear Information System (INIS)

    Prince, Norman; Hunt, Colin


    The paper reports the proceedings of a seminar organised in co-operation with the International Atomic Energy Agency, on the small and medium sized nuclear reactors (SMSNRs). The seminar was held in Lausanne, Switzerland, 1987. At the seminar there was a strong impression of a possible requirement to move away from large (more than 1000 MWe) reactors. Also smaller reactors might be more suitable for private companies and developing countries with restricted grid sizes. There was also a strong feeling that the confidence in nuclear power of both private companies and the public could be greatly increased if the designs could be based on passive heat dissipation features rather than engineered safeguards to ensure reactor safety. Light water reactors, heavy water reactors, fast reactors, high temperature reactors, other small reactor systems, safety and licensing, and marketing prospects are all discussed. (UK)

  19. Information and Communication Technology: Gender Issues in Developing Nations

    Directory of Open Access Journals (Sweden)

    Kimberly Betz Leahy


    Full Text Available As Developing Nations seek to leverage scarce resources toward the goal of achieving a developed status they must reevaluate past practices and explore available and affordable technologies. Where in-formation and communication infrastructures are weak, use of low-cost, easily distributed technologies have proven effective. Still, many developing nations have failed to incorporate a resource in great abundance, their women, to use these new technologies to greatest advantage. This paper will address the implications of women's lack of economic and educational parity, and offer examples of how the education of women through the use of information and communication technology can enhance a nation's gross domestic product (GDP.


    Directory of Open Access Journals (Sweden)



    Full Text Available The aim of this paper is to present a systematic literature review of the researches conducted in the area of risk factors and difficulties in the early development of children born after assisted conception, to systematize current knowledge in this field and allocate the factors of importance for the early intervention.In order to evaluate the published data on risk factors and early development of children born after assisted conception, an extensive literature search was conducted to identify the published papers related to the obstetric and neonatal outcome of pregnancies after assisted repro­duction technology, the incidence of multiple pregnancy and the risk of preterm delivery, the neonatal status, the mean gestational age, the average birth weight, the neuro-developmental outcomes and early cognitive and motor development. The research identified the following factors as the most important for the early intervention: increased rates of multiple gestations, prematurity, delivery by cesarean section, lower average gestational development and average birth weight, small fetal development for gestational age and low Apgar score, related to the an increased risk of developing neurological problems, such as the cerebral palsy.Accepting this research results, it can be concluded that all of these information should be available for couples seeking an Assisted Reproductive Technology (ART treatment.The success of the early intervention is directly related to the early detection and assessment that precedes this treatment, creating individual programs and evaluation of the effects of the treatment.

  1. The long-term determinants of marital fertility in the developed world (19th and 20th centuries: The role of welfare policies

    Directory of Open Access Journals (Sweden)

    Jesús Sánchez-Barricarte


    Full Text Available Background: Demographic transition theory was shattered dramatically as a result of the research carried out in the course of the Princeton European Fertility Project. There is still no consensus among demographers as to the causes underlying the fertility transition. Objective: We set out to test the explanatory capacity of certain variables which have traditionally been used to interpret the historical decline in fertility (mortality, level of education, economic development, urbanization as well as the role played by the rise of the welfare state. Methods: We collected information on different kinds of socioeconomic variables in 25 developed countries over a very long period of time. We carried out panel cointegrating regressions and country panel fixed and time effects generalized least squares. Results: We show that the decline in mortality, the increase in educational level, and economic factors all played a leading role in the historical decline in fertility. We found that the present welfare system places a remarkable burden on those who decide to have a family. Conclusions: A new kind of public social transfer model needs to be designed which will minimize the damaging consequences that our current welfare states have had with regard to fertility. Contribution: 1 The emphasis on the causal impact of the emergence and maturation of the social welfare system using Lindert's data on social transfers since the late 19th century to 1990. 2 The enormous amount of historical data compiled, as documented in the Appendix. 3 The modern panel cointegration techniques used to analyze the long- and short-term impacts of the different determinants of fertility.

  2. British Library Systems Development: The National and International Environment. (United States)

    Coward, Richard E.

    The systems approach is being applied to the re-organization of the United Kingdom Library system. The core functions to the national library organization are: (1) reference; (2) lending; (3) bibliographic services; and (4) general planning associated with the development of a national library and information system. Despite the immense potential…

  3. Military Leadership Development: A Model for the SA National ...

    African Journals Online (AJOL)

    The result of this article is an alternative model for leadership character development in the South African National Defence Force (SANDF). The SANDF reflects the racial and cultural diversity of South Africa as a nation. The need for a unifying leadership related mechanism, which will provide for the military milieu in which ...

  4. Technical Education and Vocational Training in Developing Nations (United States)

    Okolie, Ugochukwu Chinonso, Ed.


    Severe economic depression and the difficulty to acquire employment with adequate income have significant impact on a nation's social welfare. The need to provide ample educational opportunities is more imperative than ever, particularly in emerging economies. "Technical Education and Vocational Training in Developing Nations" is a…

  5. National spatial development planning in South Africa 1930-2010 ...

    African Journals Online (AJOL)

    It demonstrates that, despite the ostensible support for national planning during this period, such plans and proposals rarely had a direct impact on the conduct of government business. Using both the authors' personal experiences with the most recent such 'plan' – the National Spatial Development Perspective – they seek ...

  6. Modeling fertility curves in Africa

    Directory of Open Access Journals (Sweden)

    Ezra Gayawan


    Full Text Available The modeling of fertility patterns is an essential method researchers use to understand world-wide population patterns. Various types of fertility models have been reported in the literature to capture the patterns specific to developed countries. While much effort has been put into reducing fertility rates in Africa, models which describe the fertility patterns have not been adequately described. This article presents a flexible parametric model that can adequately capture the varying patterns of the age-specific fertility curves of African countries. The model has parameters that are interpretable in terms of demographic indices. The performance of this model was compared with other commonly used models and Akaike's Information Criterion was used for selecting the model with best fit. The presented model was able to reproduce the empirical fertility data of 11 out of 15 countries better than the other models considered.

  7. Pubertal development and fertility in survivors of childhood acute myeloid leukemia treated with chemotherapy only

    DEFF Research Database (Denmark)

    Molgaard-Hansen, Lene; Skou, Anne-Sofie; Juul, Anders


    More than 60% of children with acute myeloid leukemia (AML) become long-term survivors. Most are cured using chemotherapy without hematopoietic stem cell transplantation (HSCT). We report on pubertal development and compare self-reported parenthood among AML survivors and their siblings.......More than 60% of children with acute myeloid leukemia (AML) become long-term survivors. Most are cured using chemotherapy without hematopoietic stem cell transplantation (HSCT). We report on pubertal development and compare self-reported parenthood among AML survivors and their siblings....

  8. Final Report National Laboratory Professional Development Workshop for Underrepresented Participants

    Energy Technology Data Exchange (ETDEWEB)

    Taylor, Valerie [Texas Engineering Experiment Station, College Station, TX (United States)


    The 2013 CMD-IT National Laboratories Professional Development Workshop for Underrepresented Participants (CMD-IT NLPDev 2013) was held at the Oak Ridge National Laboratory campus in Oak Ridge, TN. from June 13 - 14, 2013. Sponsored by the Department of Energy (DOE) Advanced Scientific Computing Research Program, the primary goal of these workshops is to provide information about career opportunities in computational science at the various national laboratories and to mentor the underrepresented participants through community building and expert presentations focused on career success. This second annual workshop offered sessions to facilitate career advancement and, in particular, the strategies and resources needed to be successful at the national laboratories.

  9. Lowering Total Fertility Rates in Developing States: Security and Policy Implications for Sub-Saharan Africa (United States)


    practices, refuse arranged marriages, and avoid genital mutilation are key to lowering exposure to HIV and other sexually transmitted disease. Development...the mother), and unequal nourishment of male and female children. The aforementioned phenomena are but a few examples of women’s lack of power to

  10. The fertilizer nitrogen problem

    International Nuclear Information System (INIS)

    Olson, R.A.; Halstead, E.H.


    A world-wide fossil fuel crisis has surfaced in the past year by reason of shortage and high cost, which is felt throughout all segments of human society. Nor has the agriculture sector, with its very high demand for energy to supply its power, machinery, fertilizer, processing and transport, escaped the energy crisis. Among the agricultural inputs, fertilizer nitrogen is one of major concern. This commodity is currently in extremely short supply, world prices having more than doubled in the past year alone. Serious as this situation is to agricultural production in the highly developed countries of the world, it is a real disaster to the production potential of the developing countries. The birth of the 'Green Revolution' in those countries in the last ten years came about from an amalgamation of higher yielding varieties, improved pest and disease control, better crop watering practices, and the introduction of fertilizer nitrogen. Shortcomings in any one of these requisites invalidates the entire package. (author)

  11. Urbanization in Developing Nations: Trends, Prospects, and Policies. (United States)

    Todaro, Michael P.


    Identifies the rapid growth of cities in developing nations as one of the most significant demographic phenomena of modern times. Comparative data and policy considerations are presented for the world generally, and for Africa, Latin America, and Asia, specifically. (DB)

  12. The Church and National Development: Towards a Philosophy of ...

    African Journals Online (AJOL)

    - hundred years of evangelization within the particular area. As this has been the tag of several diocesan celebrations in the past five years, it has become relevant to examine the contribution of the Church to Nigeria's national development.

  13. Conventional Arms Transfers to Developing Nations, 1998-2005

    National Research Council Canada - National Science Library

    Grimmett, Richard F


    .... Some general data are provided on worldwide conventional arms transfers by all suppliers, but the principal focus is the level of arms transfers by major weapons suppliers to nations in the developing world...

  14. Choctaw National Wildlife Refuge : Public Use Development Plan (United States)

    Department of the Interior — This Public Use Development Plan for Choctaw National Wildlife Refuge summarizes the Refuge’s public use goals, how the Refuge will project a positive attitude, how...

  15. Educational and social class assortative mating in fertile British couples. (United States)

    Krzyżanowska, Monika; Mascie-Taylor, C G Nicholas


    Positive assortative mating for education and social position has been widely reported in a number of countries, but very few studies have tested whether or not educational or social class homogamy is related to differential fertility. This study examined the relationship between educational and social class assortative mating and fertility in a British national cohort. The analyses were based on 7452 husband-wife pairs from the British National Child Development Study (NCDS). The mean fertility was 3.22 children per couple; the number of children significantly increased from higher to lower social classes and from the more educated to the less educated. The extent of assortative mating for social class and educational level was related to fertility; as educational assortative mating decreased so did the average number of children, whereas the opposite trend was observed for social class. When assortative mating for education and social class were considered together, educational assortative mating was the more significant predictor of the number of children and educationally homogamous couples had higher fertility independent of their social class assortative mating. The relationship between assortative mating and fertility for education and social class appeared to be acting in the opposite direction.

  16. Strengthening Dairy Cooperative through National Development of Livestock Region


    Priyono; A.Priyanti


    Establishment of dairy cattle development region needs to be conducted in accordance with the national dairy industry development plan. Dairy cattle regions have been designed and equipped with infrastructure supplies, supporting facilities, technologies, finance, processing, marketing, institutional and human resources. Dairy cooperative is one of the marketing channels of milk and milk products which have strategic roles to support the national dairy industry. Collaborations between dairy c...

  17. Effects of Antioxidants on Development of In Vitro Fertilized Bovine Embryos


    Anderson, Bret L.


    Free radicals are short-lived molecules that can cause decreased embryonic development in vitro. Antioxidants are molecules that block free radical formation or guard against their harmful effects. Many studies have linked exposure of media to light and culturing of embryos in high (20%) oxygen concentrations to free radical production. Some of the antioxidants used in culture media are superoxide dismutase (SOD), catalase, zinc (II), ethylenedinitrilo tetraacetic acid (EDTA), mannitol, vitam...

  18. Seasonal and cumulative loblolly pine development under two stand density and fertility levels (United States)

    James D. Haywood


    An 8 year-old loblolly pine (Pinus taeda L.) stand was subjected to two cultural treatments for examination of seasonal and cumulative pine development. In the first treatment, pine density was either reduced by removal cutting to 2% trees per acre, at a 12- by 124 spacing, or left uncut with an original density of 1,210 trees per acre at a 6- by 6-...

  19. Population Policy and National Development in the 21st Century ...

    African Journals Online (AJOL)

    Following the concern by multi-lateral organizations such as the World Bank and the United Nations Development Programme (UNDP) about the problems of high population growth and food supply especially in the developing countries, population policy has become an integral part of their overall development policies as ...

  20. National report on sustainable development of the Slovak Republic

    International Nuclear Information System (INIS)

    Klinda, J.; Kapustova, B.; Grofova, R.; Bognarova, S.; Fabricius, A.; Kapusta, P.; Parobok, M.; Havlikova, J.


    The National Report on sustainable development of the Slovak Republic is presented. This report on the Slovak Republic after the UNO Conference of Environment and development - Rio de Janeiro, 1992 was prepared for the Johannesburg World Summit on sustainable development (26 August - 4 September 2002)

  1. Cybersecurity Strategy in Developing Nations: A Jamaica Case Study (United States)

    Newmeyer, Kevin Patrick


    Developing nations have been slow to develop and implement cybersecurity strategies despite a growing threat to governance and public security arising from an increased dependency on Internet-connected systems in the developing world and rising cybercrime. Using a neorealist theoretical framework that draws from Gilpin and Waltz, this qualitative…

  2. Cross-National Field Research in Developing Countries

    Directory of Open Access Journals (Sweden)

    Stan Karanasios PhD


    Full Text Available Cross-national field research performed in developing countries presents researchers with a number of obstacles. Challenges include creating equivalent samples, countering biases, and managing linguistic and cultural issues. In this article the author reviews the conduct of a cross-national study focusing on small tourism operators and the adoption of information communication technologies. He presents the research process, the issues encountered and how they were addressed are discussed, and a number of lessons. This article adds to our understanding of cross-national field research in developing countries and presents a number of implications for social science researchers.

  3. Fertility Development in the Baltic Countries Since 1990: a Transformation in the Context of Long-term Trends

    Directory of Open Access Journals (Sweden)

    Kalev Katus


    Full Text Available The article addresses the transformation of fertility patterns in the Baltic countries since the turn of the 1990s, in the context of long-term trends. The purpose of the study is to compare the change in fertility level, parity distribution, timing of childbearing, and the connection between marriage and childbearing in Estonia, Latvia and Lithuania, and analyze the position of the Baltic countries in a broader European perspective. Our results indicate a salient role of tempo effects in the sharp decline of period fertility measures that occurred in the region in the 1990s. Tempo-adjusted measures indicate moderately low fertility levels of 1.6-1.7 children per woman in the region. In the recent years, fertility levels have been rising in all three countries with recuperation being more vigorous in Estonia and less so in Lithuania. Estonia and Latvia also appear more advanced in terms of the spread of childbearing among cohabiting couples, with the proportion of non-marital births comparable to Scandinavian countries. The article discusses the factors underlying the observed similarities and dissimilarities in fertility patterns, pointing to the plausible demographic path dependence.

  4. Critical Roles of Vacuolar Invertase in Floral Organ Development and Male and Female Fertilities Are Revealed through Characterization of GhVIN1-RNAi Cotton Plants. (United States)

    Wang, Lu; Ruan, Yong-Ling


    Seed number and quality are key traits determining plant fitness and crop yield and rely on combined competence in male and female fertilities. Sucrose metabolism is central to reproductive success. It remains elusive, though, how individual sucrose metabolic enzymes may regulate the complex reproductive processes. Here, by silencing vacuolar invertase (VIN) genes in cotton (Gossypium hirsutum) reproductive organs, we revealed diverse roles that VIN plays in multiple reproductive processes. A set of phenotypic and genetic studies showed significant reductions of viable seeds in GhVIN1-RNAi plants, attributed to pollination failure and impaired male and female fertilities. The former was largely owing to the spatial mismatch between style and stamen and delayed pollen release from the anthers, whereas male defects came from poor pollen viability. The transgenic stamen exhibited altered expression of the genes responsible for starch metabolism and auxin and jasmonic acid signaling. Further analyses identified the reduction of GhVIN expression in the seed coat as the major cause for the reduced female fertility, which appeared to disrupt the expression of some key genes involved in trehalose and auxin metabolism and signaling, leading to programmed cell death or growth repression in the filial tissues. Together, the data provide an unprecedented example of how VIN is required to synchronize style and stamen development and the formation of male and female fertilities for seed development in a crop species, cotton. © 2016 American Society of Plant Biologists. All Rights Reserved.

  5. Use of nuclear techniques for developing integrated soil fertility management practices

    International Nuclear Information System (INIS)

    Serraj, R.; Nguyen, M.L.


    The use of isotopes such as 15 N and 13 C in the CRP on 'Integrated nutrient and water management practices for agroforestry Systems' allowed us to quantify the contribution of plant litter and N from N-fixing trees either through the root system or through the above-ground parts to increase N supply to crops and enriching soil organic matter. Through a CRP for tropical acid soils, isotopic and associated techniques have assisted us and Member States to: (i) identify crop genotypes that are tolerant to aluminium toxicity and P deficiency that are common in tropical acid soils; (ii) assess the effectiveness of a range of phosphatic fertilisers in providing phosphorus for crop requirements and (iii) quantify the enhancing effect of conservation tillage on soil quality. Significant progress is also being made in the use of isotopic techniques to assess the relative performance of traditional rice-wheat (RW) system (consisting of flooded anaerobic conditions for rice and then followed by the aerobic conditions for wheat) against various alternative technologies (e.g., rice on non-puddled soils or on raised beds, direct seeding, and zero tillage for wheat after rice) in terms of grain yield, nutrient uptake and crop water requirement. The objective is to develop isotope-based methodologies that can streamline selection of crop germplasm for high nutrient use efficiency and tolerance to nutritional deficiencies through: (i) screening of large collections of cereal and legume genotypes, their wild relatives and mutant lines for adaptation to low nutrient conditions (and/or Al toxicity), (ii) development and use of isotopic tracer techniques to evaluate crop germplasm and to understand the physiological basis for plant adaptation to nutritional stress (deficiency), and (iii) on-farm research to evaluate interactive effects of plant roots, soil nutrients and their relationship to soil micro-organisms in a series of soil-plant systems

  6. Impact of sowing density and nitrogen fertilization on Rumex obtusifolius L. development in organic winter cereal crops

    Directory of Open Access Journals (Sweden)

    Bodson, B.


    Full Text Available The control of Rumex obtusifolius L. (broad-leafed dock is very important in organic farming systems. Indeed, concerns about managing this weed without the use of herbicides is one of the major factors limiting the uptake of these systems by conventional farmers. Against this background, we analyzed the impact of two management practices on the development of R. obtusifolius populations in two winter cereal trials: spelt (Triticum spelta [L.] Thell. and triticale (×Triticosecale [A.Camus] Wittm.. The management factors were sowing density (SD and nitrogen fertilization (NF at the tillering stage. The results showed that an increase in SD and NF led to stronger crop growth and better soil coverage by the end of spring, demonstrated by a significant decrease in photosynthetic active radiation (PAR at soil level. However, although there was an SD effect, it was too weak in April to restrict an increase in R. obtusifolius populations through the recruitment of new R. obtusifolius plants. An increase in R. obtusifolius population density was also linked to an increase in the NF level, illustrating the nitrophilic character of this weed. Although an increase in SD and NF at the tillering stage led to a higher canopy density, these two practices failed to reduce R. obtusifolius density in the cereal crops. Nevertheless, cereal yields were shown to be maintained or improved. Our results indicate that, even when combining weed harrowing and some cultural weed control methods, this perennial weed is difficult to control.

  7. The Determinants of Low Fertility in India (United States)

    Dharmalingam, A.; Rajan, Sowmya; Morgan, S. Philip


    Using a conceptual framework focusing on factors that enhance or reduce fertility relative to desired family size (see Bongaarts 2001), we study fertility variation across time (1992–2006) and space (states) in India. Our empirical analyses use data from three waves of the Indian National Family Health Surveys. We find that this framework can account for a substantial portion of the variation in the TFR across the states and over time. Our estimates focus attention on the critical components of contemporary Indian fertility, especially desired family size, unwanted fertility, son preference, and fertility postponement. PMID:24993746

  8. Photosynthesis rate, chlorophyll content and initial development of physic nut without micronutrient fertilization

    Directory of Open Access Journals (Sweden)

    Elcio Ferreira dos Santos


    Full Text Available Few studies in Brazil have addressed the need for micronutrients of physic nut focusing on physiological responses, especially in terms of photosynthesis. The objective of this study was to evaluate the effects of omission of boron (B, copper (Cu, iron (Fe, manganese (Mn and zinc (Zn on Jatropha curcas L.. The experimental design was a randomized block with four replications. The treatments were complete solution (control and solution without B, Cu, Fe, Mn, and Zn. We evaluated the chlorophyll content (SPAD units, photosynthetic rate, dry matter production and accumulation of micronutrients in plants, resulting from different treatments. The first signs of deficiency were observed for Fe and B, followed by Mn and Zn, while no symptoms were observed for Cu deficiency. The micronutrient omission reduced the dry matter yield, chlorophyll content and photosynthetic rate of the plants differently for each omitted nutrient. It was, however, the omission of Fe that most affected the development of this species in all parameters evaluated. The treatments negatively affected the chlorophyll content, evaluated in SPAD units, and the photosynthetic rate, except for the omission of B. However this result was probably due to the concentration effect, since there was a significant reduction in the dry matter production of B-deficient plants.

  9. Women's education and fertility behaviour. (United States)


    The education of women results in changes in women's health status, family well being, and fertility decline. The aim of human rights and social justice is also served by increasing women's educational levels. A review of the trends in developing countries has shown that there is a strong correlation between advanced female education (10 or more years) and lower fertility. Data for 26 countries was presented in table form for total fertility rates by years of education. There were many differences in the patterns of fertility by educational level based on country level of development. The data appeared to show stronger correlations between fertility and education in more prosperous societies; culture and social structure also influenced fertility. Partial primary education has been shown in some countries to be related to increased fertility. A UN study found a curvilinear relationship between fertility and education in 14 out of 38 countries with World Fertility Surveys. There were only 3 countries with Demographic and Health Surveys which showed the curvilinear pattern. The UN study confirmed that maternal education was related to shorter durations of postpartum abstinence and short durations of lactation. Caution was urged in interpreting that an increase in a few years of schooling in a dominant rural, illiterate population would facilitate rapid fertility decline. A critical threshold effect for educational attainment was found in mainly the least developed countries. Female education has direct and indirect effects on fertility. Education may affect breast feeding patterns, contraceptive use, social norms about small families, later age at marriage, and later age at first birth. The suggestion was that education provided for reproductive choice and reduces the gap between actual and desired family size. At the country and individual level of analysis, contraceptive use was linked with education. Effective contraceptive use was still however impeded by

  10. Development of space-fertilized eggs and formation of primordial germ cells in the embryos of medaka fish (United States)

    Ijiri, K.

    In the second International Microgravity Laboratory (IML-2) mission in 1994, four small Japanese killifish (Medaka, Oryzias latipes) made a space travel of 15 days aboard a space shuttle. These four adult Medaka fish successfully mated in space for the first time among vertebrate animals. Moreover, the eggs they laid developed normally, at least in their external appearance, hatching as fry (baby fish) in space. Fish mated and laid eggs every day during the first week. Near the end of the mission most of the eggs had a well-developed body with two pigmented eyes. In total, 43 eggs were laid (detected), out of which 8 fry hatched in space, as truly `space-originated' babies. A further 30 fry hatched within 3 days after landing. This is the normal hatching rate, compared with the ground-based data. Among the 8 space-originated fry, four were killed for histological sections, and germ cells at the gonadal region were counted for each fry. Their numbers were in the range of the germ cells of the normal control fry (ground-kept samples). Thus, as embryos developed normally in their external appearance, inside the embryos the formation of primordial germ cells took place normally in space, and their migration to the genital ridges was not hindered by microgravity. The two of the remaining space-originated fry have grown up and been creating their offspring in the laboratory. This proved that the primordial germ cells formed in space were also normal from a functional point of view. The four space-travelled adult fish re-started mating and laying eggs on the 7th day after landing and continued to do so every day afterward. Fertilization rate and hatchability of these eggs were as high as the eggs laid by the laboratory-kept fish. This fact implies that in gametogenesis of adult fish, there are no specific stages of germ cells extremely susceptible to microgravity.

  11. Homeland Security: Developing National Doctrine to Guide State Strategy Development (United States)


    reminders to stop procrastinating and newfound cooking skills, I not only would never have finished, I also may have starved. xvi THIS PAGE INTENTIONALLY...doctrine in developing a homeland security doctrine. There are limitations, however, in that the military model is a narrow view. To overcome this

  12. National Competitiveness and Expenditure on Education, Research and Development

    Directory of Open Access Journals (Sweden)

    Verner Tomáš


    Full Text Available National (macroeconomic competitiveness is one of words in vogue that is mostly used by politicians, economists among others in today’s globalized world. However, the concept of competitiveness is also a very controversial issue. There are lots of concepts and approaches to a country’s overall competitiveness. In this paper, the author applies a comprehensive and established indicator used by The United Nations – The Human development index, to measure competitiveness at the national level. The main goal of this paper is to find whether higher expenditure on education, research and development leads to higher competitiveness. In evaluating the relationship, countries such as the United States, Japan and European Union countries (27 - the Triad countries were used. The panel data analysis was used to investigate the relationship and it was found that, expenditure on education and R & D positively leads to national competitiveness.

  13. An Approach to Developing a Prediction Model of Fertility Intent among HIV-Positive Women and Men in Cape Town, South Africa: A Case Study (United States)

    Bai, Dan; Leu, Cheng-Shiun; Mantell, Joanne E.; Exner, Theresa M.; Cooper, Diane; Hoffman, Susie; Kelvin, Elizabeth A.; Myer, Landon; Constant, Debbie; Moodley, Jennifer


    As a ‘case-study’ to demonstrate an approach to establishing a fertility-intent prediction model, we used data collected from recently diagnosed HIV-positive women (N=69) and men (N=55) who reported inconsistent condom use and were enrolled in a sexual and reproductive health intervention in public sector HIV care clinics in Cape Town, South Africa. Three theoretically-driven prediction models showed reasonable sensitivity (0.70 to 1.00), specificity (0.66 to 0.94), and area under the receiver operating characteristic curve (0.79 to 0.89) for predicting fertility intent at the six-month visit. A k-fold cross-validation approach was employed to reduce bias due to over-fitting of data in estimating sensitivity, specificity, and area under the curve. We discuss how the methods presented might be used in future studies to develop a clinical screening tool to identify HIV-positive individuals likely to have future fertility intent and who could therefore benefit from sexual and reproductive health counseling around fertility options. PMID:27294266

  14. Development of a national code of practice for structural masonry ...

    African Journals Online (AJOL)

    The problems and constraints faced by most developing countries, particularly Ghana, in developing codes of practice for structural masonry are highlighted. The steps that must be undertaken through the coordinated efforts of the National Standards Boards, Research Institutions, Universities and Professional Bodies in the ...

  15. The Spatial Development Framework for implementation of National ...

    African Journals Online (AJOL)

    National Urbanization Policies (NUPs) are of particular importance in countries with rapid urbanization. Both for diagnosis for development of NUPs and for planning of implementation of NUPs we present a new methodology called the Spatial Development Framework (SDF). The SDF analyzes and describes with ...

  16. Integrating development and climate policies: National and international benefits

    NARCIS (Netherlands)

    Kok, M.; Metz, B.; Verhagen, J.


    What lessons for policy makers at national and international level can be drawn from the growing experiences of reconciling development and climate change? The key to achieving this is to approach the problem from the development perspective, since that is where in most countries the priority lies.

  17. Developing and maintaining national food safety control systems ...

    African Journals Online (AJOL)

    The establishment of effective food safety systems is pivotal to ensuring the safety of the national food supply as well as food products for regional and international trade. The development, structure and implementation of modern food safety systems have been driven over the years by a number of developments.

  18. Competitive intelligence and national development: the role of ...

    African Journals Online (AJOL)

    Competitive intelligence (CI) is the process of developing actionable foresight regarding competitive dynamics and non-market factors that can be used to enhance competitive advantage. It is a relevant tool for strategic decision making which in return impacts national development. Though CI is an organizational function ...

  19. Risk-Based Approach to Developing National Residue Sampling Plan


    Scientific Committee of the Food Safety Authority of Ireland


    A ranking system for veterinary medicinal products and medicated feed additives has been developed as a tool to be applied in a risk-based approach to the residue testing programme for foods of animal origin in the National Residue Control Plan. In the context of food sampling and residue testing for the National Residue Control Plan, there is firstly, the risk to human health from residues of chemical substances in food and secondly, the issue of non-compliance with regulations relating ...

  20. Education for Sustainable Development at the United Nations Conference on Sustainable Development (Rio+20) (United States)

    Journal of Education for Sustainable Development, 2012


    The United Nations Conference on Sustainable Development (Rio+20) was held in Rio de Janeiro, Brazil, 20-22 June 2012, marking the twentieth anniversary of the United Nations Conference on Sustainable Development in Rio de Janeiro in 1992 and the tenth anniversary of the 2002 World Summit on Sustainable Development in Johannesburg. With more than…

  1. Minapadi Development Strategy in Supporting National Food Security (United States)

    Lestari, Sri; Bambang, Azis Nur


    Efforts to achieve food security, especially food self-sufficiency, face severe challenges. Intensification needs to be done in optimizing the existing land by applying integrated agriculture. One of them is by integrating agriculture and fishery aspect with implementation of minapadi. Minapadi cultivation has actually grown since a long time, but in the course of time this system Began displaced because of pesticides and chemical fertilizers. Become flagship Minapadi back in line with the increasing public awareness of the importance of sustainable environment, health, increasing demand for organic products that are free from pesticide residues which means safe for consumption. Minapadi is the answer to the fulfillment of people's need for carbohydrate and protein food. Blending the fulfillment of carbohydrates is rice as the staple food of most people with the fulfillment of animal protein from fish commodities to add nutritional value. In realizing the food security strategy is required Minapadi development. This descriptive research aims to find out various minapadi development strategies in several regions with different methods based on the literature and previous studies. The result is the formulation of minapadi development strategy in an area not necessarily can be applied in other areas.This occurs because of differences in setting criteria/ variables based on the characteristics and potential of a region, the strengths and opportunities, as well as the weaknesses and threats that the area may encounter.

  2. National park development in China: conservation or commercialization? (United States)

    Wang, Guangyu; Innes, John L; Wu, Sara W; Krzyzanowski, Judi; Yin, Yongyuan; Dai, Shuanyou; Zhang, Xiaoping; Liu, Sihui


    The rapid development of parks and ecotourism in China has attracted worldwide attention, not only for the beauty of the landscape that the parks are protecting but also for their abundant and often unique biodiversity. However, in some areas, the development of ecotourism has actually led to the degradation of local ecological, economic, and social systems. Using National Forest Parks for demonstration, this article analyzes the current political, institutional, legal, environmental, and economic issues concerning National Parks in China, and examines their potential future development. Although the intention of National Park systems in China is to raise environmental quality, and to protect biodiversity and social livelihoods, their success has varied. Future success will be measured by their capacity to reduce poverty, to promote long-term rehabilitation of wildlife habitats, and to simultaneously protect Chinese culture and biodiversity.

  3. Resource Management As Panacea For Sustainable National Economic Development And National Unity

    Directory of Open Access Journals (Sweden)

    Akanbi Oluwajuwon Mayomi


    Full Text Available This paper examines Resource Management as a Panacea for Sustainable National Economic Development and National Unity. The nation has been besieged by numerous problems due to poor resource management. These problems include corruption health implications poverty and inequality in income distribution ethnic crisis pollutions and it has also resulted in economic losses. These problems have militated against the countrys ability to create wealth for the present and future generation. The paper also looked at the concept of conservation and sustainability and their relationship with resource management. The main thrust of the recommendations was hinged on the problems mentioned. These recommendations include making revenue from resources more equitably distributed compensating the people of the area through the development of infrastructures like health facilities and provision of pipe borne water making and enforcing laws that will reduce pollution and development of capital projects.

  4. An investment in children's health, nutrition and education is the foundation stone for all national development. (United States)

    Kalra, S


    A medical student at the Christian Medical College in Ludhiana, India, won first place in the First Annual Dr. S.M. Gupta Memorial Essay Contest with this essay on investing in the health, nutrition, and education of India's children. The health, nutrition, and education condition of India's children is substandard. 10% of infants die before their first birthday. 15% of children die before age 5. Many Indian children suffer from diarrhea and acute respiratory infections. Investment in immunization, oral rehydration therapy, hygiene, and health education would prevent many of these deaths and illnesses. Illness and death cost parents time, energy, and money. Children suffering from malnutrition and sickness cannot concentrate on learning. The state of today's children foretells the state of tomorrow's adults, work force, and leaders. Poor nutrition and health contribute to India's substandard economic productivity. India has 14% of the world's population, but produces only 1.2% of its gross national product. Even though India was the first country to have a national family planning program, its fertility and population growth rates are high. Investment in children's health would show parents the benefits of planning their families. It would also improve India's poor performance in sports and war as well as national prestige and socioeconomic development. The considerable number of illiterates reflect India's failure to invest in education. Females have a lower literacy rate than males. Girls in India suffer much discrimination. They receive less food, less medical care, less opportunities for education, and less recreation. National development depends on the active participation of girls. Prevention is the key: nourish the children, educate them, and keep them healthy.

  5. Monolithic circuit development for RHIC at Oak Ridge National Laboratory

    Energy Technology Data Exchange (ETDEWEB)

    Alley, G.T.; Britton, C.L. Jr.; Kennedy, E.J.; Newport, D.F.; Wintenberg, A.L.; Young, G.R. [Oak Ridge National Laboratory, TN (United States)


    The work performed for RHIC at Oak Ridge National Laboratory during FY 91 is presented in this paper. The work includes preamplifier, analog memory, and analog-digital converter development for Dimuon Pad Readout, and evaluation and development of preamplifier-shapers for silicon strip readout. The approaches for implementation are considered as well as measured data for the various circuits that have been developed.

  6. Genetically-induced Estrogen Receptor Alpha mRNA (Esr1) Overexpression Does Not Adversely Affect Fertility or Penile Development in Male Mice (United States)

    Heath, John; Abdelmageed, Yazeed; Braden, Tim D.; Williams, Carol S.; Williams, John W.; Paulose, Tessie; Hernandez-Ochoa, Isabel; Gupta, Rupesh; Flaws, Jodi A.; Goyal, Hari O.


    Previously, we reported that estrogen receptor alpha mRNA (Esr1) or protein (ESR1) overexpression resulting from neonatal exposure to estrogens in rats was associated with infertility and mal-developed penis characterized by reduced length and weight and abnormal accumulation of fat cells. The objective of this study was to determine if mutant male mice overexpressing Esr1 are naturally infertile or have reduced fertility and/or develop abnormal penis. The fertility parameters, including fertility and fecundity indices, numbers of days from the day of cohabitation to the day of delivery, and numbers of pups per female, were not altered from controls, as a result of Esr1 overexpression. Likewise, penile morphology, including the length, weight, and diameter and os penis development, was not altered from controls. Conversely, weights of the seminal vesicles and bulbospongiosus and levator ani (BS/LA) muscles were significantly (P testosterone concentration were not different from controls. Hence, the genetically-induced Esr1 overexpression alone, without an exogenous estrogen exposure during the neonatal period, is unable to adversely affect the development of the penis as well as other male reproductive organs, except limited, but significant, reductions in weights of the seminal vesicles and BS/LA muscles. PMID:20930192

  7. Determinants of fertility levels in Kafanchan, Nigeria

    Directory of Open Access Journals (Sweden)

    D. O. Ogbonnas


    Fertility is high while mortality is low. However, as a measure towards demographic readjustment, a further reduction in the level of mortality may lead to decline in fertility. Some future planning implications of the existing fertility' evels are discussed in the light of the current population policy and development planning in the country.

  8. DNA methylation in porcine preimplantation embryos developed in-vivo or produced by in-vitro fertilization, parthenogenetic activation and somatic cell nuclear transfer

    DEFF Research Database (Denmark)

    Deshmukh, Rahul Shahaji; Østrup, Olga; Østrup, Esben


    ), in vitro fertilized (IVF), somatic cell nuclear transfer (SCNT) and parthenogenetically activated (PA) embryos were evaluated for DNA methylation quantification at different developmental stages. Fertilized (IV and IVF) one-cell stages lacked a substantial active demethylation of the paternal genome......DNA demethylation and remethylation are crucial for reprogramming of the differentiated parental/somatic genome in the recipient ooplasm upon somatic cell nuclear transfer. Here, we analyzed the DNA methylation dynamics during porcine preimplantation development. Porcine in vivo developed (IV....... Embryos produced under in vitro conditions had higher levels of DNA methylation than IV. A lineage-specific DNA methylation (hypermethylation of the inner cell mass and hypomethylation of the trophectoderm) was observed in porcine IV late blastocysts, but was absent in PA- and SCNT-derived blastocysts...

  9. DNA methylation in porcine preimplantation embryos developed in vivo and produced by in vitro fertilization, parthenogenetic activation and somatic cell nuclear transfer

    DEFF Research Database (Denmark)

    Deshmukh, Rahul Shahaji; Østrup, Olga; Østrup, Esben


    ), in vitro fertilized (IVF), somatic cell nuclear transfer (SCNT) and parthenogenetically activated (PA) embryos were evaluated for DNA methylation quantification at different developmental stages. Fertilized (IV and IVF) one-cell stages lacked a substantial active demethylation of the paternal genome......DNA demethylation and remethylation are crucial for reprogramming of the differentiated parental/somatic genome in the recipient ooplasm upon somatic cell nuclear transfer. Here, we analyzed the DNA methylation dynamics during porcine preimplantation development. Porcine in vivo developed (IV....... Embryos produced under in vitro conditions had higher levels of DNA methylation than IV. A lineage-specific DNA methylation (hypermethylation of the inner cell mass and hypomethylation of the trophectoderm) was observed in porcine IV late blastocysts, but was absent in PA- and SCNT-derived blastocysts...

  10. Nutrition and development of infants from poor rural areas. III. Maternal nutrition and its consequences on fertility. (United States)

    Chavez, A; Martinez, C


    To test the hypothesis that malnutrition alters fertility, the reproductive pattern of a poor rural community with a high natality rate was studied. A late menarche age (15.5 +or- 1.5 years) and an early menopause (40.4 +or- 2.5 years) were found and resulted in a short reproductive period of 25 years. In all, there were 8.8 +or- 2.7 pregnancies and 7.9 +or- 2.9 deliveries during this period, but only 4.8 +or- 2.2 children reached adulthood. A longitudinal observation was made of 2 groups which were similar in all respects, except that one was supplemented and the other was not. Both groups lactated the entire time between pregnancies as well. The control group recovered fertility 14.0 +or- 4.0 months after delivery while the supplemented group did after only 7.5 +or- 2.6 months; this difference, as well as the difference in recovery times in the experimental group before and after supplementation, were highly significant (P0.001). It may be concluded that undernutrition reduced mothers' fertility in 2 potential ways. It may reduce a woman's reproductive life and it determines an increase in the period between deliveries of more than 40%. Therefore, the high natality rate in this community should not be explained by high individual fertility but rather by the sociocultural characteristics of the community.

  11. Development of a web-based runoff forecasting tool to guide fertilizer and manure application in the Chesapeake Bay watershed (United States)

    Managing the land application of fertilizers and manures is critical to protecting water quality in the Chesapeake Bay watershed. While modern nutrient management tools are designed to help farmers with their long-term field management planning, they do not support daily decisions such as when to a...

  12. Strengthening Dairy Cooperative through National Development of Livestock Region

    Directory of Open Access Journals (Sweden)



    Full Text Available Establishment of dairy cattle development region needs to be conducted in accordance with the national dairy industry development plan. Dairy cattle regions have been designed and equipped with infrastructure supplies, supporting facilities, technologies, finance, processing, marketing, institutional and human resources. Dairy cooperative is one of the marketing channels of milk and milk products which have strategic roles to support the national dairy industry. Collaborations between dairy cooperatives and smallholder farmers within a district region have to be done based on agricultural ecosystems, agribusiness system, integrated farming and participatory approach. This may improve dairy cooperatives as an independent and competitive institution. Strengthening dairy cooperatives in national region dairy cattle was carried out through institutional inventory and dairy cooperatives performance; requirement of capital access, market and networks as well as education and managerial training; certification and accreditation feasibility analysis and information and technology utilization. Establishment of emerging dairy cooperatives towards small and micro enterprises is carried out by directing them to establish cooperatives which have legal certainty and business development opportunities. The impact of strengthening dairy cooperative may support dairy cattle development through increase population and milk production. Sustainable dairy cattle development needs to be supported by regional and national government policies.

  13. National Models of Technological Development: a Comparative Analysis

    Directory of Open Access Journals (Sweden)

    Evgeniy V. Balatskiy


    Full Text Available In the article, suggestions are made for the development of methodological approaches to using factor analysis of technological development of countries and revealing the related weaknesses. The article presents an overview of the ideas for the study of such categories as national innovation system, its elements – the scientific and technological sector and approaches to efficiency measurement and comparative analysis of national innovation systems of different countries. For the purposes of assessing the scientific and technological potential of countries, a method of constructing a scientific-technological balance which links the efficiency of the national economy to the sphere of generation of knowledge and technologies, is proposed. Analysis of the relative scientific and technological parameters showed that each country has its advantages and disadvantages for research and technological development. In particular, in China, the scale of research sector is not adequate to the scale of the national economy and its growth rate; Poland has been experiencing low returns from the sphere of applied research; in Russia the bottleneck for scientific and technological development is low efficiency of the scientific work expressed in the publication activity. Overall, the study showed that the scientific and technological balance constructing method is a successful one in assessing the impact of knowledge generation and technology development on the level of productivity in the economy.

  14. Infrastructure development for electrical mobility: a Nordic perspective on national and cross-national challenges

    DEFF Research Database (Denmark)

    Klitkou, Antje; Iversen, Eric; Borup, Mads

    The formative EU transport policy focuses on region-wide initiatives to promote more sustainable transportation, including electrical mobility. The vow to integrate or coordinate the ongoing development of electrical mobility into a Europe-wide recharging-infrastructure confronts a number...... level. This paper studies the national cases of Norway and Denmark within the context of the seemingly homogenous Nordic region. The paper focuses on the different approaches taken at the national level to build battery electric vehicle (BEV) recharging infrastructure. Norway and Denmark provide apt......, contrasting focal points. Despite its position as a large fossil-fuel exporter and its mountainous topography, Norway exhibits high – and rapidly growing – levels of penetration of BEVs. Denmark is developing a connected nation-wide infrastructure. In both countries the integration of the existing...

  15. Desenvolvimento radicular do algodoeiro em resposta à localização do fertilizante Cotton root development as affected by fertilizer placement

    Directory of Open Access Journals (Sweden)

    Fábio Suano de Souza


    Full Text Available A utilização de adubos pode-se tornar prejudicial caso o fertilizante não seja localizado adequadamente. No presente trabalho foram estudados o crescimento radicular do algodoeiro (Gossypium hirsutum, o crescimento inicial e a nutrição da planta, considerando o local de aplicação do fertilizante. O estudo foi realizado em vasos com parede de vidro. O fertilizante foi colocado a 5,0 cm abaixo e 0,0, 2,5, 5,0 e 10,0 cm ao lado das sementes. O crescimento radicular foi avaliado a cada três dias e, aos 21 dias após a emergência, as plantas foram coletadas, sendo avaliada a produção de matéria seca e a absorção de macronutrientes. A aplicação de fertilizante proporcionou crescimento inicial mais vigoroso do sistema radicular mesmo em solo previamente corrigido e adubado, o que é importante no estabelecimento da cultura. Somente houve bom crescimento inicial do sistema radicular e da parte aérea do algodoeiro quando o fertilizante foi aplicado de 5,0 a 10,0 cm ao lado e 5,0 cm abaixo das sementes.Unless fertilizer is properly placed in the soil it can be harmful. This experiment was conducted to study cotton (Gossypium hirsutum root growth and initial plant development and nutrition as affected by fertilizer placement. Cotton plants were grown in pots with a glass wall. The fertilizer was applied 5.0 cm under the seed row and 0, 2.5, 5.0 and 10.0 cm beside the seed row. Root growth was evaluated every 3 days, and 21 days after emergence the plants were harvested. Dry matter production and macronutrient absorption were evaluated. Even in previously limed and fertilized soil, localized fertilizer application reinforced the initial growth of cotton roots, which is very important for a good crop establishment in the field. Normal root growth and adequate initial plant development was only observed when the fertilizer was placed 5.0 cm below and from 5.0 to 10.0 cm distance from the seed row.

  16. Women Leadership and its Relevance to National Development in ...

    African Journals Online (AJOL)

    Women Leadership and its Relevance to National Development in the 21st Century. ... UJAH: Unizik Journal of Arts and Humanities ... Over time in history, a few women who have been entrusted with the leading role to manage human and material resources have more often than not proved the same point that, given ...

  17. National Spatial Data Clearinghouses: Worldwide development and impact

    NARCIS (Netherlands)

    Crompvoets, J.W.H.C.


    Over the last few years many countries have spent considerable resources on developing their own National Spatial Data Infrastructure (NSDI) in order to manage and utilise spatial data assets more efficiently, reduce the cost of data production, and eliminate duplication of data acquisition. One of

  18. Engaging the Tanzanian Diaspora in National Development: What ...

    African Journals Online (AJOL)

    Keywords: Diaspora Engagement, National Development, Tanzania. 1. Darlene K. Mutalemwa is a ... having its unique features in regards to home country, migration patterns and historical experiences. ..... recipients, supplement their income and provide them with funds that can be used for consumption, savings, or ...

  19. The spread of nuclear weapons among nations: militarization or development

    International Nuclear Information System (INIS)

    Khan, A.Q.


    The paper reviews nuclear proliferation among nations. Nuclear weapons promotion and proliferation are discussed, including both motivation and lack of motivation to manufacture nuclear weapons. The failure of the Non-Proliferation Treaty is examined with respect to vertical and horizontal proliferation, and the containment of horizontal proliferation. Risks of nuclear war by accident are outlined, as well as nuclear weapon development. (UK)

  20. Participation of Women in the Third National Fadama Development ...

    African Journals Online (AJOL)

    This study assessed participation of women in the third National Fadama Development Programme (NFDP-III) in Edo State, Nigeria. A sample of 150 women were randomly selected from the Fadama Users Groups (FUGs) drawn from the three zones of the State. A structured questionnaire administered through interview ...

  1. Marketing activities and national development: is there a link ...

    African Journals Online (AJOL)

    The main objective of this study is to establish the link that exists between marketing and national development without losing sight of the intervening variables that might exist between them. The study suggested comparative advantage (CAD), resource-use efficiency (RUET), wealth creation (WECRE) as the possible ...

  2. Thailand's National Nutritional Program : Lessons in Management and Capacity Development


    Heaver, Richard; Kachondam, Yongyout


    Thailand's community nutrition program has been the most successful in Asia. This paper looks at what made it work from a management and capacity development point of view. Key lessons are identified in the following areas: Building a strong consensus at national and local levels about the importance of nutrition as an investment in the country's future, rather than as a welfare expenditur...

  3. Impact of National Fadama Development Project II on Rice farmers ...

    African Journals Online (AJOL)

    This study examined the impact of National Fadama Development Project II on the profitability of rice farmers and assessed the extent to which the various innovations disseminated by the project were adopted by the rice farmer beneficiaries. The project which had all operating expenses cofinanced by the various key ...

  4. Linguistic Diversity, Pluralism and National Development in Africa ...

    African Journals Online (AJOL)

    The Principle of Attitude Engineering (PAE) is expected to effect a positive change of attitude, culminating in a change of mindset congruent with the paradigm shift of national development anchored on pluralism. This model of Language Planning ensures the empowerment of linguistic minorities, provides for a reduction of ...

  5. Perceived Benefits of National Fadama Development Project III ...

    African Journals Online (AJOL)

    The study was conducted to appraise the perceived benefits of third national fadama development project III among rural farmers in Kwara state, Nigeria. A multi-stage random sampling technique was employed in selecting 225 Fadama III users as respondents. Data were collected by well trained fadama community ...

  6. Phases to face in national medical leadership development

    NARCIS (Netherlands)

    Keijser, Wouter Alexander; Wilderom, Celeste P.M.; Poorthuis, Max Bastiaan; Tweedie, Judith; Lees, Peter; Dickson, Graham


    Increasing economic and organizational challenges call physicians in action to engage in medical leadership (ML) roles. Yet, in only six of the 195 countries the content of ML development has recently been articulated in the form of comprehensive national schemes or programs. Despite increasing

  7. Igbo Language as a Crucial Instrument for National Development ...

    African Journals Online (AJOL)

    ... Igbo language which dwindles day-by-day, irrespective of the fact that it promises to be a crucial tool for national development, especially considering its commercial background. This paper, therefore, addresses the problem, with a view to resuscitating and repositioning the Igbo language to assume this all important role.

  8. Revisiting the Utility of Industrial Sociology in National Development ...

    African Journals Online (AJOL)

    Sociology as an academic discipline has been entrenched in many Nigerian universities, however, not much is known about how the discipline has contributed or has been contributing to the national development. Although some scholars have discussed some contributions of sociology in the emerging economy like ...

  9. The United Nations Conference on Science and Technology for Development. (United States)

    Kaplan, M M


    Despite a long gestation period in preparation for the United Nations Conference on Science and Technology for Development (UNCSTD) and overall expenditures estimated at some $50 million for this Vienna held conference, there were no dramatic results. The Conference faced trying to reach some compromise agreement on the following main points: 1) a global information system, and governing principles for the transfer of technology; 2) institutional arrangements, particularly within the United Nations system, which would ensure a high status for an Intergovernmental Committee on Science and Technology for development; and 3) automatically renewable financing to be supplied primarily by the industrialized countries to implement the Plan of Action. Arguments concerning these points occupied 2 committees for 10 working days of the conference. The outcome of negotiations on these identified points included the following: 1) minimal progress in facilitating access to industrial information, and to patent rights and transfer of technology in general; 2) the proposed Intergovernmental Committee on Science and Technology for Development will be open to all interested countries and will report to the United Nations General Assembly through ECOSOC; 3) coordination of the post-conference program of the Plan of Action will be centered in the office of Director-General for Development and International Economic Cooperation at the United Nations; 4) $250 million was named as the target for the first 2 years of operation; and 5) groups of experts will be convened on an ad hoc basis to advise on various matters.

  10. Cultural Diplomacy and National Development: A Study of the ...

    African Journals Online (AJOL)

    Findings indicate that, while cultural diplomacy promotes Nigeria.s image and international cooperation, it also enhances national development with income gotten from foreign investors and tourists. The study concludes that cultural diplomacy is a valuable, indeed, vital tool for Nigeria to win more friends, get international ...

  11. Great Expectations: Teacher Learning in a National Professional Development Programme (United States)

    Armour, Kathleen M.; Makopoulou, Kyriaki


    This paper reports findings from an evaluation of a national continuing professional development (CPD) programme for teachers in England. Data showed that the localised implementation, opportunities for interactive learning, and "collective participation" were positive factors. Research participants reported difficulties, however, in…

  12. History and National Development | Oyeranmi | Journal of History ...

    African Journals Online (AJOL)

    Volumes of works have been written on the subject of the relevance of history to national development in Nigeria. To „.non historians.. history teaches no particular skill “since the primary focus of history is the past... Does history still serve any purpose especially in the 21st century? What are those values embedded in ...

  13. Teacher Education: A Panacea for National Development in Nigeria

    African Journals Online (AJOL)


    social, economic and political transformation of the nation. This development has thrust a lot of responsibilities on teachers who are the major operators of any education system. It is therefore not an overstatement that the professionalization of teaching and making the teacher the centre of educational reform in Nigeria, will ...

  14. Development of a national environmental monitoring programme for radionuclides - Sweden

    International Nuclear Information System (INIS)

    Wallberg, P.J.; Hubbard, L.M.


    In parallel with the enforcement of the Environmental Code in 1999, the Swedish parliament adopted 15 national environmental quality objectives that aim towards a sustainable development for the country. The government's primary environmental objective is to hand over a society to the next generation in which the major environmental problems have been solved. One of the quality objectives is 'A Safe Radiation Environment' of which the Swedish Radiation Protection Authority (SSI) is the responsible authority. In order to follow the progress towards this objective SSI is currently developing a national environmental monitoring and assessment programme for radionuclides. Many countries have monitoring programmes in the vicinity of nuclear power plants and nuclear industries, as Sweden has also had for many years. The current Swedish effort is a development beyond the local monitoring programmes to incorporate radiation assessment at a national level. This includes long-term issues such as identification of ecological processes that can concentrate radionuclides, and assessment of activities other than nuclear industries that lead to radioactive releases. One of the expected results of this monitoring programme is an improved framework for assessing the dynamics and impact of radionuclide transfer and containment in different ecosystems. This paper will focus on the development and implementation of the framework for a national monitoring programme, include some examples of environments that have been identified as areas of particular concern, and describe an approach to protect species with different ecological prerequisites. (author)

  15. Corruption and National Development in Nigeria's Fourth Republic ...

    African Journals Online (AJOL)

    This article assessed the impact of corruption on national development in Nigeria's democratic dispensation. Secondary source of data was employed in this study. The paper revealed that bad governance, poor service delivery, inadequate infrastructural amenities, poor management of public enterprise, moral decadence ...

  16. Algeria : National Environmental Action Plan for Sustainable Development


    World Bank


    This staff sector assessment note accompanies the recently completed national environmental action plan for sustainable development (NEAP-SD), which, as an output of the Industrial Pollution Control Project in Algeria, focused on charting a new course for environmental management in the country, based on an objective assessment of past policy, and institutional failures, on a new consensus...

  17. Maternal health challenges and prospects for national development ...

    African Journals Online (AJOL)

    ... to investigate challenges to maternal health during pregnancy as a barrier to national development. Data was generated by questionnaire and in-depth interview and analysis were made by simple percentage and content analysis respectively. The findings were discussed within the Health Belief Model and concluded by ...

  18. Fertility Treatment and Childhood Epilepsy - a Nationwide Cohort Study

    DEFF Research Database (Denmark)

    Kettner, Laura Ozer; Kesmodel, Ulrik Schiøler; Ramlau-Hansen, Cecilia Høst


    BACKGROUND: Fertility treatment includes hormonal stimulation of the woman and in vitro manipulation of gametes and embryos that may influence prenatal brain development. We aimed to investigate the association between fertility treatment and childhood epilepsy, including specific types of treatm......BACKGROUND: Fertility treatment includes hormonal stimulation of the woman and in vitro manipulation of gametes and embryos that may influence prenatal brain development. We aimed to investigate the association between fertility treatment and childhood epilepsy, including specific types...... of treatment and indications, as well as subtypes of epilepsy. METHODS: In this nationwide birth cohort study, we included all pregnancies in Denmark resulting in live-born singletons, 1995-2003. Children conceived by fertility treatment and children developing epilepsy (until 2013) were identified from Danish...... national registers. RESULTS: A total of 565,116 pregnancies were included; 8,071 children (1.4%) developed epilepsy. Children conceived after ovulation induction or intrauterine insemination had a slightly higher risk of childhood epilepsy (hazard ratio [HR]: 1.15; 95% confidence interval [CI]: 1.00, 1...

  19. Preserving Fertility while Battling Cancer (United States)

    Some oncologists neglect to discuss the possibility of treatment-related infertility with patients of reproductive age. Researchers are developing decision aids to help patients make an informed, carefully considered decision about fertility.

  20. International Space Station: National Laboratory Education Concept Development Report (United States)


    The International Space Station (ISS) program has brought together 16 spacefaring nations in an effort to build a permanent base for human explorers in low-Earth orbit, the first stop past Earth in humanity's path into space. The ISS is a remarkably capable spacecraft, by significant margins the largest and most complex space vehicle ever built. Planned for completion in 2010, the ISS will provide a home for laboratories equipped with a wide array of resources to develop and test the technologies needed for future generations of space exploration. The resources of the only permanent base in space clearly have the potential to find application in areas beyond the research required to enable future exploration missions. In response to Congressional direction in the 2005 National Aeronautics and Space Administration (NASA) Authorization Act, NASA has begun to examine the value of these unique capabilities to other national priorities, particularly education. In early 2006, NASA invited education experts from other Federal agencies to participate in a Task Force charged with developing concepts for using the ISS for educational purposes. Senior representatives from the education offices of the Department of Defense, Department of Education, Department of Energy, National Institutes of Health, and National Science Foundation agreed to take part in the Task Force and have graciously contributed their time and energy to produce a plan that lays out a conceptual framework for potential utilization of the ISS for educational activities sponsored by Federal agencies as well as other future users.

  1. Infectious Diseases in a Global Economy - Consequences for Developing Nations


    Peter, McDonald AM


    Since the end of the cold war the world economy has become dominated by Western [largely US] interests. In this period there have developed several pandemics or epidemics of infectious diseases that have affected most nations. HIV, SARS, Avian Influenza, Hepatitis-C, Bovine Spongiform Encephalopathy, drug-resistant TB, viral zoonoses, are specific examples that will be discussed in terms of their genesis, economic impact and consequences for ways of life in the range of economies – developed,...

  2. An Update on the United Nations Millennium Development Goals. (United States)

    Campbell, Della Anne

    The United Nations Millennium Development Goals initiative, designed to meet the needs of the world's poorest, ended in 2015. The purpose of this article is to describe the progress made through the Millennium Development Goals and the additional work needed to address vulnerable populations worldwide, especially women and children. A description of the subsequent Sustainable Development Goals, enacted to address the root causes of poverty and the universal need for development for all people, is provided. Copyright © 2017 AWHONN, the Association of Women’s Health, Obstetric and Neonatal Nurses. Published by Elsevier Inc. All rights reserved.

  3. Liquid Organic Fertilizers for Sustainable Agriculture: Nutrient Uptake of Organic versus Mineral Fertilizers in Citrus Trees. (United States)

    Martínez-Alcántara, Belén; Martínez-Cuenca, Mary-Rus; Bermejo, Almudena; Legaz, Francisco; Quiñones, Ana


    The main objective of this study was to compare the performance of two liquid organic fertilizers, an animal and a plant-based fertilizer, with mineral fertilization on citrus trees. The source of the fertilizer (mineral or organic) had significant effect in the nutritional status of the organic and conventionally managed mandarins. Nutrient uptake, vegetative growth, carbohydrate synthesis and soil characteristics were analyzed. Results showed that plants fertilized with animal based liquid fertilizers exhibited higher total biomass with a more profuse development of new developing organs (leaves and fibrous roots). Liquid organic fertilization resulted in an increased uptake of macro and micronutrients compared to mineral fertilized trees. Moreover, organic fertilization positively affected the carbohydrate content (fructose, glucose and sucrose) mainly in summer flush leaves. Liquid organic fertilization also resulted in an increase of soil organic matter content. Animal-based fertilizer, due to intrinsic composition, increased total tree biomass and carbohydrate leaves content, and led to lower soil nitrate concentration and higher P and Mg exchangeable in soil extract compared to vegetal-based fertilizer. Therefore, liquid organic fertilizers could be used as an alternative to traditional mineral fertilization in drip irrigated citrus trees.

  4. Evaluation of biodegradable polymers as encapsulating agents for the development of a urea controlled-release fertilizer using biochar as support material. (United States)

    González, M E; Cea, M; Medina, J; González, A; Diez, M C; Cartes, P; Monreal, C; Navia, R


    Biochar constitutes a promising support material for the formulation of controlled-release fertilizers (CRFs). In this study we evaluated the effect of different polymeric materials as encapsulating agents to control nitrogen (N) leaching from biochar based CRFs. Nitrogen impregnation onto biochar was performed in a batch reactor using urea as N source. The resulting product was encapsulated by using sodium alginate (SA), cellulose acetate (CA) and ethyl cellulose (EC). Leaching potential was studied in planted and unplanted soil columns, monitoring nitrate, nitrite, ammonium and urea concentrations. After 90 days, plants were removed from the soil columns and plant yield was evaluated. It was observed that the ammonium concentration in leachates presented a maximum concentration for all treatments at day 22. The highest concentration of N in the leachates was the nitrate form. The crop yield was negatively affected by all developed CRFs using biochar compared with the traditional fertilization. Copyright © 2014 Elsevier B.V. All rights reserved.

  5. What Is Fertility Preservation? (United States)

    ... Share Facebook Twitter Pinterest Email Print What is fertility preservation? Fertility preservation is the process of saving or protecting ... children in the future. Who can benefit from fertility preservation? People with certain diseases, disorders, and life ...

  6. Fertility Clinic Success Rates (United States)

    ... Defects ART and Autism 2013 Assisted Reproductive Technology Fertility Clinic Success Rates Report Recommend on Facebook Tweet ... Additional Information About ART in the United States. Fertility Clinic Tables Introduction to Fertility Clinic Tables [PDF - ...

  7. Patient-centered Fertility Care: From Theory to Practice

    Directory of Open Access Journals (Sweden)

    Fatemeh Jafarzadeh-Kenarsari


    Full Text Available Background & aim: Healthcare areas, especially fertility care (commonly accompanied with high emotions, as well as long-term and recurring treatment periods could exclusively benefit from patient-centered care (PCC. Despite evident advantages of PCC, this approach has not been practiced as a routine procedure in current clinical environments yet, even in western developed countries. Therefore, this review aimed to evaluate the significance and different aspects of PCC, while emphasizing on patient-centered fertility care, its challenges, and applicable recommendations in this regard. Methods: This narrative review was conducted on 29 relevant medical and clinical papers (published during 1990-2015 collected using various national and international databases (e.g., SID, Magiran, Medlib, Google scholar, Proquest, Pubmed, Wiley, Science direct, and Scopus. Key words and phrases used in this review were “infertility”, “fertility care”, “childlessness”, “patient-centered care”, “patient-centered fertility care” “shared decision-making”, “infertile patient preferences”, and “patient involvement in fertility care”. Results: According to the literature, implementation challenges of patient-centered fertility care were reported as different individual and organizational factors. These factors include lack of professional motivation to change, underestimating the significance of patient-centeredness by healthcare professionals, difficulty in translation of feedback into concrete measures, lack of time and financial resources, insufficient experience of healthcare professionals with regard to identification of needs and preferences of patients, traditional organizational culture, and common misconceptions. Conclusion: Promotion of patient-centered fertility services requires the identification of infertile needs and priorities of individuals, designation of interventional and supportive programs based on sociocultural

  8. Fertility Herbs: Do They Enhance Fertility? (United States)

    ... get pregnant. I've seen many ads for fertility herbs and supplements. Do they work? Answers from ... for infertility. Unfortunately, the research on so-called fertility herbs and supplements is inconclusive and based on ...

  9. Developing a national physical activity plan: the Kuwait example. (United States)

    Ramadan, Jasem; Vuori, Ilkka; Lankenau, Becky; Schmid, Tom; Pratt, Michael


    A rapid increase in economic well-being and urbanization in Kuwait have been accompanied by profound changes in lifestyle, including low levels of physical activity in all population groups. These changes have contributed to a high prevalence of overweight and obesity and to the escalation of the non-communicable disease rates, particularly coronary heart disease, stroke, hypertension and diabetes. The evolution of physical activity promotion, internationally, and a series of related meetings in Kuwait and neighboring countries, have started to generate an awareness among health authorities of the importance of physical activity in health promotion and disease prevention. A National Physical Activity Committee has been formed to design and implement a National Physical Activity Plan, which could also serve as a model for other countries. The authors describe the background and principles behind the development of the National Plan, summarize a template based upon the Kuwait experience and share the lessons learned from these efforts.

  10. IQs Predict Differences in the Technological Development of Nations from 1000 BC through 2000 AD (United States)

    Lynn, Richard


    National IQs and measures of technological development given by Comin, Easterly and Gong (2010) are presented for 133 nations for the year 1000 BC, for 134 nations for 0 AD, for 120 nations for 1500 AD and for 133 nations for 2000 AD. It is shown that national IQs are significantly correlated with national differences in technological development…

  11. Advantage: industry and First Nations developing strong business relationships

    International Nuclear Information System (INIS)

    O'Meara, D.


    The history of confrontations, recriminations, ultimatums, demands and endless negotiations between the oil and gas industry and First Nations communities is told. Important as the history of the conflict is, it is even more important that a mechanism has been found to resolve w these endless quarrels, giving rise to a new oil and gas economy in the 1990s and a new era of resource development in Western Canada. Land settlements, partnership and joint ventures between industry and First Nations communities, negotiating economic and social benefits into business contracts, believed to be an impossible task only a few short years ago , has gone full circle and has become a competitive edge, an admittedly costly and time consuming exercise, but absolutely necessary to be successful in First Nations relations. Conversely, one of the big problems facing First Nations Councils is educating their own members on the benefits of working with oil and gas companies. This is not an easy task since the benefits are sometimes not visible, and when deals hammered out in council with company executives are often filtered through contractors and sub-contractors and deals specifying employment do not materialize. Despite these problems, the experience of several of the companies active on First Nations lands is that it is possible to overcome a history of insensitivity and establish a business environment in which both sides have reason to consider themselves winners

  12. Building Human Rights, Peace and Development within the United Nations

    Directory of Open Access Journals (Sweden)

    Christian Guillermet Fernández


    Full Text Available War and peace have perpetually alternated in history. Consequently, peace has always been seen as an endless project, even a dream, to be in brotherhood realized by everyone across the earth. Since the XVII century the elimination of war and armed conflict has been a political and humanitarian objective of all nations in the world. Both the League of Nations and the United Nations were conceived with the spirit of eliminating the risk of war through the promotion of peace, cooperation and solidarity among Nations. The Universal Declaration of Human Rights and the subsequent human rights instruments were drafted with a sincere aspiration of promoting the value of peace and human rights worldwide. International practice shows the close linkage between the disregard of human rights and the existence of war and armed conflict. It follows that the role of human rights in the prevention of war and armed conflict is very important. Since 2008 the Human Rights Council has been working on the ‘Promotion of the Right of Peoples to Peace.’ Pursuant resolutions 20/15 and 23/16 the Council decided firstly to establish, and secondly to extend the mandate of the Open-Ended Working Group (OEWG aimed at progressively negotiating a draft United Nations declaration on the right to peace. The OEGW welcomed in its second session (July 2014 the approach of the Chairperson-Rapporteur, which is basically based on the relationship between the right to life and human rights, peace and development.

  13. The national strategy for a sustainable development 2009-2013

    International Nuclear Information System (INIS)


    This document first presents the content of the French national strategy for a sustainable development, and notably its nine strategic challenges: climate change and energy, sustainable transport and mobility, sustainable consumption and production, sustainable management of biodiversity and natural resources, public health, prevention and risk management, international challenges in terms of sustainable development and struggle against poverty, knowledge society, and governance. While discussing these challenges, the report outlines the need to make this strategy more constraining for public authorities, to structure this strategy about transitions towards a sustainable development, and to give room to dialogue

  14. Pellet fueling development at Oak Ridge National Laboratory

    International Nuclear Information System (INIS)

    Foster, C.A.; Milora, S.L.; Schuresko, D.D.; Combs, S.K.; Lunsford, R.V.


    A pellet injector development program has been under way at the Oak Ridge National Laboratory (ORNL) since 1976 with the goals of developing D 2 , T 2 pellet fuel injectors capable of reliable repetitive fueling of reactors and of continued experimentation on contemporary plasma devices. The development has focused primarily on two types of injectors that show promise. One of these injectors is the centrifuge-type injector, which accelerates pellets in a high speed rotating track. The other is the gas or pneumatic gun, which accelerates pellets in a gun barrel using compressed helium of H 2 gas

  15. Education Differences in Intended and Unintended Fertility (United States)

    Musick, Kelly; England, Paula; Edgington, Sarah; Kangas, Nicole


    Using a hazards framework and panel data from the National Longitudinal Survey of Youth (1979-2004), we analyze the fertility patterns of a recent cohort of white and black women in the United States. We examine how completed fertility varies by women's education, differentiating between intended and unintended births. We find that the education…

  16. The Political and Territorial Development of Nations without States

    Directory of Open Access Journals (Sweden)

    Jernej Zupančič


    ambitions towards national independence. The territorial and political reconstruction of nation-states has been successful, but it did not solve all ethnic problems. The European political map reveals another interesting phenomenon: a double state for some nations. These are particularly typical for the Balkans. Because of political and territorial development after the Second World War and during the transition period in the 1990s and beyond, the principle of immutable political borders (logically encompassing the creation of new nation-states as well led to further political and territorial divisions and (in fact, paradoxically fragmentation. Some of these “inner” autonomous territories are functioning as de facto states. The cases of the Turkish Republic of Northern Cyprus or Republika Srpska in Bosnia-Herzegovina are good examples of these processes. This development has not garnered much political support in most European countries or at the EU level. However, it is an undesirable reality and is certainly one of changes among the political and territorial (or even greater challenges for the Europe of tomorrow. It forces a reexamination of the phenomenon and value of nations. The existence of nations without states represents a potential for the creation of new (nation states.

  17. Managing air quality in a rapidly developing nation: China (United States)

    Fang, Ming; Chan, Chak K.; Yao, Xiaohong

    As the world gets ready to begin the second decade of the twenty-first century, global climate change has been recognized as a real threat to civilization as we know it. The rapid and successful economic growth of developing nations, particularly China and India, is contributing to climate change. The route to initial economic success in China followed that of the developed nations through the development of industries. Unfortunately, China's environmental protection efforts have not been the same as in developed countries because China is vastly different culturally, socially, economically and, especially, politically from developed nations. When China started to deal with environmental concerns in the late 1970s, it took advantage of the experiences of other countries in establishing environmental standards and regulations, but it did not have a model to follow when it came to implementing these standards and regulations because of the abovementioned differences. Economically, China is transitioning from an agricultural base into an industrial base; however, even now, 60% of the population remains farmers. China has been and still is heavily dependent upon coal for energy, resulting in serious atmospheric particulate pollution. While growing efforts have been expended on the environment, at this juncture of its economic development, China would be well served to revisit the traditional "develop first and clean up later" approach and to find a balance between development and protecting the environment. Against this backdrop, a reflective look of the effort to manage air quality from 1949-2008 (with an emphasis on the past 30 years) in China is presented in this paper. The environmental component of the 2008 Olympic Games is examined as a special example to illustrate the current measures being used to improve air quality in China.

  18. Sperm preparation for fertilization


    Gadella, B.M.


    Description This book contains 19 chapters that discuss theoretical and applied andrology for domestic, zoo and wild animals. Topics include semen and its constituents; sperm production and harvest; determinants of sperm morphology; sperm preparation for fertilization; practical aspects of semen cryopreservation; evaluation of semen in the andrology laboratory; genetic aspects of male reproduction; emerging techniques and future development of semen evaluation and handling and applied androlo...

  19. Fertility preservation during cancer treatment: clinical guidelines (United States)

    Rodriguez-Wallberg, Kenny A; Oktay, Kutluk


    The majority of children, adolescents, and young adults diagnosed with cancer today will become long-term survivors. The threat to fertility that cancer treatments pose to young patients cannot be prevented in many cases, and thus research into methods for fertility preservation is developing, aiming at offering cancer patients the ability to have biologically related children in the future. This paper discusses the current status of fertility preservation methods when infertility risks are related to surgical oncologic treatments, radiation therapy, or chemotherapy. Several scientific groups and societies have developed consensus documents and guidelines for fertility preservation. Decisions about fertility and imminent potentially gonadotoxic therapies must be made rapidly. Timely and complete information on the impact of cancer treatment on fertility and fertility preservation options should be presented to all patients when a cancer treatment is planned. PMID:24623991

  20. Cryopreservation of ovarian tissue for fertility preservation in a large cohort of young girls: focus on pubertal development. (United States)

    Jensen, A K; Rechnitzer, C; Macklon, K T; Ifversen, M R S; Birkebæk, N; Clausen, N; Sørensen, K; Fedder, J; Ernst, E; Andersen, C Yding


    Is there an association between the need for medical puberty induction and the diagnosis or treatment received in girls who have undergone cryopreservation of ovarian tissue for fertility preservation? There was a clear association between the intensity of treatment received and requirement for medical puberty induction but no association with the diagnosis. Although it cannot be predicted which girls will become infertile or develop premature ovarian insufficiency (POI) following intensive chemotherapy or irradiation, patients who are at high risk of POI should be offered ovarian tissue cryopreservation (OTC). This includes girls who are planned to receive either high doses of alkylating agents, conditioning regimen before stem cell transplantation (SCT), total body irradiation (TBI) or high radiation doses to the craniospinal, abdominal or pelvic area. This is a retrospective cohort study. In total, 176 Danish girls under 18 years of age have had OTC performed over a period of 15 years. An overview of the girls' diagnoses and mean age at OTC as well as the number of deceased is presented. Of the 176 girls, 38 had died and 46 girls were still younger than 12 years so their pubertal development cannot be evaluated yet. For the 60 girls who had OTC performed after 12 years of age, the incidence of POI was evaluated and in the group of 32 girls who were younger than 12 years at OTC, the association between the diagnosis and received treatment and the requirement for medical puberty induction was examined. The need for medical puberty induction was assessed in 32 girls who were prepubertal at the time of OTC. Indications for OTC were allogeneic SCT for leukaemia, myelodysplastic syndrome or benign haematological disorders, autologous SCT for lymphoma or sarcoma, and irradiation to the pelvis or to the spinal axis. The mean age at OTC of the 176 girls were 11.3 years. The two most prevalent diagnoses of the 176 girls were malignant tumours and malignant haematological

  1. Fertilizers in cereals crops. Effect of fertilization in grain quality

    International Nuclear Information System (INIS)

    Melaj, Mariana


    In the last years the yields of the maize cultivation in the Pampeana production region have constantly increased, foreseeing higher increases of yield in the next years. Such increase is due, between other motives, to the use of hybrids of higher potential yield. There is a direct relation between the yield potential of a genotype and the nutrients demand, fact that constitutes one of the geneticists concerns. Maize hybrids reach its maximum expression when the plant is cultivated in good supplied soils with balanced quantities of nutrients that in several cases are reached with the practice of fertilization. The quantitative and qualitative vegetal response to the use of phosphate fertilizers depend of soils, of the environmental conditions, of fertilizer and the way of its application as well as of the maize hybrid that was used. To direct the practice of fertilization towards the reposition of the soil nutrients extracted by genotypes of high yield without producing excesses that increase costs and put in danger the environment, it is necessary to know the real coefficient used by the plants of the phosphorus available in the soils. The isotopic methodology allows to distinguish the phosphorus coming from two nutrient sources: soil and fertilizer, even in the juvenile phase of vegetal development and to evaluate the efficiency of fertilizers in plant nutrition. The objective of the present work was to evaluate the use of phosphorus coming from one of the phosphorus source available (soil, fertilizer), that should allow to increase and make more specific the knowledge's level of the different maize hybrids. This is obtained by determination of the grade of use of nutrient (of the soil) and of the nutrient of fertilizers, evaluating the qualitative and quantitative responses to fertilization


    Directory of Open Access Journals (Sweden)



    Full Text Available The development of the Chilean military industry is closely related to the growing of the national industry. Similarly to the way the history of the Army and the country are tightly related, the history of the military engineering is an example of organic growth when compared to its civilian counterpart. Collaboration instead of competition is the distinctive seal that best shows the development of weaponry, explosives, cartography and nuclear power. This collaboration have lasted with the years and we can afirm today that the relationship within civilian professionals and technicians and their military counterparts has reached an state that has never seen before. The governmental policies that fund R&D of initiatives that facilitate the science and technology study and research, come of a futuristic vision, born in the rim of the independent movements, driven naturally by the need of self sustain as sovereign nations.

  3. Technology-Enhanced Learning in Developing Nations: A review

    Directory of Open Access Journals (Sweden)

    Shalni Gulati


    Full Text Available Learning ‘using’ technologies has become a global phenomenon. The Internet is often seen as a value-neutral tool that potentially allows individuals to overcome the constraints of traditional elitist spaces and gain unhindered access to learning. It is widely suggested that online technologies can help address issues of educational equity and social exclusion, and open up democratic and accessible educational opportunities. The national governments and non-governmental agencies who fund educational endeavours in developing countries have advocated the use of new technologies to reduce the cost of reaching and educating large numbers of children and adults who are currently missing out on education. This paper presents an overview of the educational developments in open, distance, and technology-facilitated learning that aim to reach the educationally deprived populations of the world. It reveals the challenges encountered by children and adults in developing countries as they attempt to access available educational opportunities. The discussion questions whether, in face of these challenges, developing nations should continue to invest money, time, and effort into e-learning developments. Can technology-enhanced learning help address the poverty, literacy, social, and political problems in developing countries?

  4. United Nations: preparing to examine energy and sustainable development

    International Nuclear Information System (INIS)

    Radka, Mark


    This article examines the progress on sustainable development at the international level, and discusses the forthcoming meeting of the Commission for Sustainable Development (CSD-9) and the review of the progress of the Earth Summit in Rio in 1992. Details are given of the anticipated Third Assessment report of the Intergovernmental Panel on Climate Change which is expected to increase pressure to reduce emissions of greenhouses gases, the link between policies of sustainable development and renewable energy, the challenge of the growing demand for energy in the developing countries and the need to mitigate against environmental damage, and the setting up of the Sustainable Energy Advisory Facility (SEAF) by the United Nations Environment Programme to aid developing countries to participate in the CSD-9 process

  5. United Nations: preparing to examine energy and sustainable development

    Energy Technology Data Exchange (ETDEWEB)

    Radka, Mark [United Nations Environment Programme, Paris (France)


    This article examines the progress on sustainable development at the international level, and discusses the forthcoming meeting of the Commission for Sustainable Development (CSD-9) and the review of the progress of the Earth Summit in Rio in 1992. Details are given of the anticipated Third Assessment report of the Intergovernmental Panel on Climate Change which is expected to increase pressure to reduce emissions of greenhouses gases, the link between policies of sustainable development and renewable energy, the challenge of the growing demand for energy in the developing countries and the need to mitigate against environmental damage, and the setting up of the Sustainable Energy Advisory Facility (SEAF) by the United Nations Environment Programme to aid developing countries to participate in the CSD-9 process.

  6. Obesity: modern man's fertility nemesis


    Cabler, Stephanie; Agarwal, Ashok; Flint, Margot; Du Plessis, Stefan S.


    The obesity pandemic has grown to concerning proportions in recent years, not only in the Western World, but in developing countries as well. The corresponding decrease in male fertility and fecundity may be explained in parallel to obesity, and obesity should be considered as an etiology of male fertility. Studies show that obesity contributes to infertility by reducing semen quality, changing sperm proteomes, contributing to erectile dysfunction, and inducing other physical problems related...

  7. Symposium on chemistry and biotechnology for national development. Proceedings

    International Nuclear Information System (INIS)

    Garba, A.; Ogunmola, G.B.


    This document is the full proceedings of the symposium on chemistry and biotechnology for national development held at SHESTCO in 1995. It contains the full texts of a forward, opening and special remarks, welcome and keynote addresses and abstracts and texts of 21 technical papers. The subjects covered included information technology,chemistry and biotechnology in agriculture, health care and industrial development. Additionally, the abstracts in respect of 19 other papers are included. We wish to thank the Coordinator of SHESTCO for making available this proceedings

  8. Experiences of developed European countries in solving issues related to national minorities


    Raduški Nada


    Contemporary geopolitical change, inter-ethnic conflicts and clashes, the connection between minority and territorial problems, considerably influence the quality of inter-state relations and preservation of global peace and security. National problems and ethnic confrontations have found particularly fertile soil in the Balkans, although they are known in democratic West European countries as well, despite high human rights standards. However, even though such problems deserve special attent...

  9. Fertility preservation for female cancer patients. (United States)

    Harada, Miyuki; Osuga, Yutaka


    An improvement in the survival rates of cancer patients and recent advancements in assisted reproductive technologies have led to remarkable progress in oncofertility and fertility preservation treatments. Currently, for adults and postpubertal girls, oocyte or embryo cryopreservation is an established method. If their cancer treatment cannot be postponed for 2 weeks, ovarian tissue cryopreservation is offered as an experimental technique. For prepubertal girls, ovarian tissue cryopreservation is the only option. As for ovarian protection, there is insufficient evidence regarding the effectiveness of GnRH agonist in fertility preservation. In the past decade, the concept of fertility preservation for cancer patients has been rapidly spreading, but at present only a small part of young cancer patients receive fertility preservation services. It is partly because of the lack of adequate provision of information on fertility preservation and the lack of referral from oncology to the fertility clinic. In Japan, the clinical practice guidelines for fertility preservation in childhood, adolescent and young adult cancer patients was issued last year by the Japan Society of Clinical Oncology (JSCO). It would help Japanese health care providers, including oncologists and reproductive specialists, to increase their knowledge on fertility preservation for cancer patients and move forward the fertility preservation services. For further progress, it is also needed to establish a national registration system of fertility preservation for cancer patients to evaluate the safety and efficacy of the current management.

  10. On sustainable development of population and national economy. (United States)

    Tian, X


    This article offers a strategy for achieving sustainable development of population and the national economy in China. It is argued that economic growth and population growth must be in balance and coordinated. In 1993 it was estimated that a national economic growth rate of 4.03-4.60% was needed in order to balance the natural population growth rate of 1.15% at the existing standard of living. When the national economy grows faster than population in the life expectancy time period, overpopulation can be checked. Population must be balanced with sufficient means for subsistence. The key measure of sustainable development is the ratio between the size of the working-age population and the means of production. The number of people in the labor force is positively related to fixed assets and negatively related to the labor force's technical equipment. China's problems include weak industrial fixed assets, a surplus labor force, and slow growth in industrial and agricultural productivity. Potential solutions are to shift employment from a cultivation-oriented rural economy to a diversified rural economy, to increase the pace of change to an industrial and commercial economy, and to increase the pace of change to nonmaterial production and to raising employment efficiency. Solutions are dependent upon improvement in the quality of population, which means increased levels of education. China still has 181,610,00 people who are illiterate or semi-illiterate among the working-age population. Sustainable development also relies on active promotion of social support for the elderly by a pension system, family support, and reemployment of the elderly. Surplus labor should be absorbed by the service industry. Population structure and economic development are more advanced in coastal areas that have 41% of total population. Inland areas should develop labor-intensive, technology-intensive, and investment-intensive industries. Northwest areas need an educated population

  11. Economic Performance Analysis of National Research and Development Project

    International Nuclear Information System (INIS)

    Kim, S. S.; Yun, S. W.; Kim, S. E.


    There are a lot of differences between these two evaluation programs in terms of their main objectives, assessment items, and evaluation methods by item. When considering the recent evaluation trend of being more concerned with the objective and scientifically well-founded base of judgment than the qualitative results data, there seems to be much supplement and improvement points in both evaluation programs. Firstly, the MSIP's evaluation program which is known as 'The performance analysis of national R and D program in Korea is applying the principle of ex-post evaluation for the overall performances of R and D activities focusing on the scientific and technological outputs, economic effects, and social performances such as the training of science and engineering personnel. Its report has been done and published by the collaboration of MSIP and KISTEP(Korea Institute of Science and Technology Evaluation and Planning). There seems to be a trend that the economic contributions to the national economy and the industries by national R and D projects have been underestimated due to the difficulties of not presenting properly the reliable quantitative effects even though they have contributed not only to the real economy and economic growth but to the industrial productions and public benefits. The key reasons to this phenomenon might be the deficiency of perception for evaluation tools and methodologies development and the original difficulty of evaluation for R and D performances. Especially the evaluation results for national R and D projects could impact on the investment decision on the long-term national R and D program, with being based on the investment efficiency or the necessity and urgency which might be represented by evaluation results

  12. Migration and Fertility in Pakistan




    The phenomena of migration and fertility has not drawn much attention in Pakistan. A few studies based on census data, the National bnpact Survey 1968-69 and the Population Growth Survey 1968-71 showed higher crude birth rates for rural areas than for urban areas. However, recent studies showed higher urban fertility in Pakistan. In view of the increasing rate of rural migration to the urban areas it is important to understand the contribution of migration to popUlation growth. The main objec...

  13. Development of a Nationally Coordinated Evaluation Plan for the Ghana National Strategy for Key Populations. (United States)

    Reynolds, Heidi W; Atuahene, Kyeremeh; Sutherland, Elizabeth; Amenyah, Richard; Kwao, Isaiah Doe; Larbi, Emmanuel Tettey

    Just as HIV prevention programs need to be tailored to the local epidemic, so should evaluations be country-owned and country-led to ensure use of those results in decision making and policy. The objective of this paper is to describe the process undertaken in Ghana to develop a national evaluation plan for the Ghana national strategy for key populations. This was a participatory process that involved meetings between the Ghana AIDS Commission (GAC), other partners in Ghana working to prevent HIV among key populations, and MEASURE Evaluation. The process included three two-day, highly structured yet participatory meetings over the course of 12 months during which participants shared information about on-going and planned data and identified research questions and methods. An evaluation plan was prepared to inform stakeholders about which data collection activities need to be prioritized for funding, who would implement the study, the timing of data collection, the research question the data will help answer, and the analysis methods. The plan discusses various methods that can be used including the recommendation for the study design using multiple data sources. It has an evaluation conceptual model, proposed analyses, proposed definition of independent variables, estimated costs for filling data gaps, roles and responsibilities of stakeholders to carry out the plan, and considerations for ethics, data sharing and authorship. The experience demonstrates that it is possible to design an evaluation responsive to national strategies and priorities with country leadership, regardless of stakeholders' experiences with evaluations. This process may be replicable elsewhere, where stakeholders want to plan and implement an evaluation of a large-scale program at the national or subnational level that is responsive to national priorities and part of a comprehensive monitoring and evaluation system.

  14. The national science agenda as a ritual of modern nation-statehood: The consequences of national "Science for National Development" projects (United States)

    Drori, Gili S.

    This study is a comparative investigation of the ways by which the globalization of modern science affects the characteristics of different nation-states. Whereas much research and policy discussion focuses on science as an instrumental, or technical, system with immediate consequences for national conditions, such as economic development, science should also be regarded as a general cultural framework, which is highly institutionalized at the global level. As such, the institutionalization of science at both the global and national levels affects a wide variety of national properties. Following this line of reasoning, this dissertation study employs cross-national and longitudinal data and multiple-indicator methods to show national-level consequences of scientific expansion on the processes of rationalization and modernization of social and political life. It appears that the cross-national expansion of science practice results in, or is associated with, a variety of measures of (a) the standardization of civil and governmental procedures and (b) the expansion of the political rights and political engagement. I conclude from these empirical findings that scientization encourages (a) greater general societal rationalization and (b) expanded notions of social actorhood and agency. This evidence demonstrates how the globalization of science alters local conditions, both civil and political, by supporting the institutionalization of bureaucratic practices and participatory politics. Thus, the expansion of science--clearly affected by global processes--carries a general secularized faith in a rationalized world and in human agency. In this sense, the practice of science is a national ritual, whose social role is as a legitimacy-providing institution, rather then a technically functional institution. On a broader level, the study emphasizes the relations between globalization processes and the sovereignty of the nation-state. I conclude that science carries modernist

  15. Report of the consultants' meeting on the use of nuclear techniques to develop management practices for increasing crop production and soil fertility in acid soils

    International Nuclear Information System (INIS)

    Thomas, Richard; Zapata, Felipe


    A Consultants' Meeting on 'The use of nuclear techniques to develop management practices for increasing crop production and soil fertility in acid soils' was held in Vienna at the IAEA headquarters from March 1-3, 1999. The meeting was attended by six consultants with expertise in tropical acid soils drawn from International Agricultural Research Organisations and universities together with staff members of the Joint FAO/IAEA Division. The consultants' presentations reviewed advances in approaches for the sustainable intensification of agricultural productivity in tropical acid soils in Latin America, Africa and South East Asia. The consultants also provided recommendations on the formulation and implementation of the future CRP

  16. Steroid-inducible BABY BOOM system for development of fertile Arabidopsis thaliana plants after prolonged tissue culture. (United States)

    Lutz, Kerry A; Martin, Carla; Khairzada, Sahar; Maliga, Pal


    We describe a steroid-inducible BABY BOOM system that improves plant regeneration in Arabidopsis leaf cultures and yields fertile plants. Regeneration of Arabidopsis thaliana plants for extended periods of time in tissue culture may result in sterile plants. We report here a novel approach for A. thaliana regeneration using a regulated system to induce embryogenic cultures from leaf tissue. The system is based on BABY BOOM (BBM), a transcription factor that turns on genes involved in embryogenesis. We transformed the nucleus of A. thaliana plants with BBM:GR, a gene in which the BBM coding region is fused with the glucocorticoid receptor (GR) steroid-binding domain. In the absence of the synthetic steroid dexamethasone (DEX), the BBM:GR fusion protein is localized in the cytoplasm. Only when DEX is included in the culture medium does the BBM transcription factor enter the nucleus and turn on genes involved in embryogenesis. BBM:GR plant lines show prolific shoot regeneration from leaf pieces on media containing DEX. Removal of DEX from the culture media allowed for flowering and seed formation. Therefore, use of BBM:GR leaf tissue for regeneration of plants for extended periods of time in tissue culture will facilitate the recovery of fertile plants.

  17. The development of national economy and family planning in China. (United States)

    Xu, D


    China has made great strides in family planning and in developing her national economy during the period of the 6th 5-year plan. In 1980, China's tasks were to develop the national economy and to provide her people with enough to eat and wear. By 1986, these needs had been met. The average annual growth rate for the national gross output value of industry and agriculture may reach 10% during the 6th 5-year plan and should be approximately 7% in the 7th 5-year plan. China's future goal is for all her people to be well off at the turn of the century. Controlling population growth is one of the most important steps in reaching this goal China's population growth rates were 23.33 per 1000 in 1971 and dropped to 10.81 per 1000 in 1984. Although China's family planning program advocates one child per couple, 70% of the total married women of childbearing age have 2 or 3 children. Continued publicity and education and improved medical care should gradually decrease the birth rate even more. The author cites Engels in arguing that it is one of the superiorities of the socialist system to make population growth consciously fit for the development of material production. He refutes an American view that China's population would automatically decrease with the development of a free economy and offers the US's 12 million unemployed in 1982 and 2 million homeless in 1985 as evidence that a free economy also results in overpopulation. He concludes that further demographic research should be conducted and should implement China's family planning program with different measures suited to local conditions at different stages.

  18. Establishing national noncommunicable disease surveillance in a developing country: a model for small island nations

    Directory of Open Access Journals (Sweden)

    Angela M. Rose

    Full Text Available ABSTRACT Objective To describe the surveillance model used to develop the first national, population-based, multiple noncommunicable disease (NCD registry in the Caribbean (one of the first of its kind worldwide; registry implementation; lessons learned; and incidence and mortality rates from the first years of operation. Methods Driven by limited national resources, this initiative of the Barbados Ministry of Health (MoH, in collaboration with The University of the West Indies, was designed to collect prospective data on incident stroke and acute myocardial infarction (MI (heart attack cases from all health care facilities in this small island developing state (SIDS in the Eastern Caribbean. Emphasis is on tertiary and emergency health care data sources. Incident cancer cases are obtained retrospectively, primarily from laboratories. Deaths are collected from the national death register. Results Phased introduction of the Barbados National Registry for Chronic NCDs (“the BNR” began with the stroke component (“BNR–Stroke,” 2008, followed by the acute MI component (“BNR–Heart,” 2009 and the cancer component (“BNR–Cancer,” 2010. Expected case numbers projected from prior studies estimated an average of 378 first-ever stroke, 900 stroke, and 372 acute MI patients annually, and registry data showed an annual average of about 238, 593, and 349 patients respectively. There were 1 204 tumors registered in 2008, versus the expected 1 395. Registry data were used to identify public health training themes. Success required building support from local health care professionals and creating island-wide registry awareness. With spending of approximately US$ 148 per event for 2 200 events per year, the program costs the MoH about US$ 1 per capita annually. Conclusions Given the limited absolute health resources available to SIDS, combined surveillance should be considered for building a national NCD evidence base. With prevalence

  19. Developing the African national health research systems barometer. (United States)

    Kirigia, Joses Muthuri; Ota, Martin Okechukwu; Senkubuge, Flavia; Wiysonge, Charles Shey; Mayosi, Bongani M


    A functional national health research system (NHRS) is crucial in strengthening a country's health system to promote, restore and maintain the health status of its population. Progress towards the goal of universal health coverage in the post-2015 sustainable development agenda will be difficult for African countries without strengthening of their NHRS to yield the required evidence for decision-making. This study aims to develop a barometer to facilitate monitoring of the development and performance of NHRSs in the African Region of WHO. The African national health research systems barometer algorithm was developed in response to a recommendation of the African Advisory Committee for Health Research and Development of WHO. Survey data collected from all the 47 Member States in the WHO African Region using a questionnaire were entered into an Excel spreadsheet and analysed. The barometer scores for each country were calculated and the performance interpreted according to a set of values ranging from 0% to 100%. The overall NHRS barometer score for the African Region was 42%, which is below the average of 50%. Among the 47 countries, the average NHRS performance was less than 20% in 10 countries, 20-40% in 11 countries, 41-60% in 16 countries, 61-80% in nine countries, and over 80% in one country. The performance of NHRSs in 30 (64%) countries was below 50%. An African NHRS barometer with four functions and 17 sub-functions was developed to identify the gaps in and facilitate monitoring of NHRS development and performance. The NHRS scores for the individual sub-functions can guide policymakers to locate sources of poor performance and to design interventions to address them.

  20. Alternative Ways to Control Fertility in Indonesia

    Directory of Open Access Journals (Sweden)

    D Dahroni


    Full Text Available An effort for reducing fertility in developing countries like Indonesia, is a real initiative to decrease the population growth rate. The succes of family planning programme in reducing fertility of Indonesia, has been confessed by UNO, and as a result, president Suharto has been rewarded a United Nation Population Award. Besides it is considered to make another effort beyond family planning programmes, among other things are: to raise age of marriage, future cousciousness, moral, and health education. Those programmes can be carried out through formal and informal education as well. The aim of family planning programme is to create a small family of lawful marriage and have heredity. In order to have a quantity and a good quality of heredity we are likely to become, then, there should be a planning of giving birth. Nevertheless, campaign motivation to raise age of marriage for young generation in rural as well as in urban, is one of the main efforts to reduce fertility rates.

  1. Cooperative research and development opportunities with the National Cancer Institute (United States)

    Sybert, Kathleen


    The Office of Technology Development (OTD) of the National Cancer Institute (NCI) is responsible for negotiating Cooperative Research and Development Agreements (CRADAs), whereby the knowledge resulting from NCI investigators' government-sponsored research is developed in collaboration with universities and/or industry into new products of importance for the diagnosis and treatment of cancer and acquired immunodeficiency syndrome (AIDS). The NCI has recently executed a unique 'clinical trials' CRADA and is developing a model agreement based upon it for the development and commercialization of products for the diagnosis and treatment of cancer and AIDS. NCI drug screening, preclinical testing, clinical trials, and AIDS program capabilities form the basis for this new technology development/technology transfer vehicle. NCI's extensive drug screening program and 'designer foods' program serve as potential sources of investigational new drugs (INDs) and cancer preventatives. Collaborations between NCI and pharmaceutical companies having the facilities, experience, and expertise necessary to develop INDs into approved drugs available to the public are being encouraged where the companies have proprietary rights to INDs, or where NCI has proprietary rights to INDs and invites companies to respond to a collaborator announcement published in the Federal Register. The joint efforts of the NCI and the chosen collaborator are designed to generate the data necessary to obtain pharmaceutic regulatory approval from the Food and Drug Administration (FDA) to market the drugs developed, and thereby make them available to health care providers for the diagnosis and treatment of cancer and AIDS.

  2. Fertility, immigration, and the fight against climate change. (United States)

    Earl, Jake; Hickey, Colin; Rieder, Travis N


    Several philosophers have recently argued that policies aimed at reducing human fertility are a practical and morally justifiable way to mitigate the risk of dangerous climate change. There is a powerful objection to such "population engineering" proposals: even if drastic fertility reductions are needed to prevent dangerous climate change, implementing those reductions would wreak havoc on the global economy, which would seriously undermine international antipoverty efforts. In this article, we articulate this economic objection to population engineering and show how it fails. We argue, first, that the economic objection paints an inaccurate picture of the complicated relationship between demographic change and economic growth, and second, that any untoward economic effects of fertility reduction can be mitigated with additional policies. Specifically, we argue that supplementing fertility reduction with policies that facilitate the emigration of younger people from developing nations to developed nations could allow for both global reductions in GHG emissions and continued economic stability. Further, we show that moral arguments against such unprecedented increases in immigration are unsuccessful. We conclude that population engineering is a practical and morally justifiable tool for addressing the twin evils of climate change and global poverty. © 2017 John Wiley & Sons Ltd.

  3. Modification of Experimental Protocols for a Space Shuttle Flight and Applications for the Analysis of Cytoskeletal Structures During Fertilization, Cell Division , and Development in Sea Urchin Embryos (United States)

    Chakrabarti, Amitabha; Stoecker, Andrew; Schatten, Heide


    To explore the role of microgravity on cytoskeletal organization and skeletal calcium deposition during fertilization, cell division, and early development, the sea urchin was chosen as a model developmental system. Methods were developed to employ light, immunofluorescence, and electron microscopy on cultures being prepared for flight on the Space Shuttle. For analysis of microfilaments, microtubules, centrosomes, and calcium-requiring events, our standard laboratory protocols had to be modified substantially for experimentation on the Space Shuttle. All manipulations were carried out in a closed culture chamber containing 35 ml artificial sea water as a culture fluid. Unfertilized eggs stored for 24 hours in these chambers were fertilized with sperm diluted in sea water and fixed with concentrated fixatives for final fixation in formaldehyde, taxol, EGTA, and MgCl2(exp -6)H2O for 1 cell to 16 cell stages to preserve cytoskeletal structures for simultaneous analysis with light, immunofluorescence, and electron microscopy, and 1.5 percent glutaraldehyde and 0.4 percent formaldehyde for blastula and plueus stages. The fixed samples wre maintained in chambers without degradation for up to two weeks after which the specimens were processed and analyzed with routine methods. Since complex manipulations are not possible in the closed chambers, the fertilization coat was removed from fixation using 0.5 percent freshly prepared sodium thioglycolate solution at pH 10.0 which provided reliable immunofluorescence staining for microtubules. Sperm/egg fusion, mitosis, cytokinesis, and calcium deposition during spicule formatin in early embryogenesis were found to be without artificial alterations when compared to cells fixed fresh and processed with conventional methods.


    Directory of Open Access Journals (Sweden)

    Vasyl Syrvatka


    Full Text Available Silver nanoparticles are the most rapidly growing classes of nanoproducts. In this study, we investigated the influence of subcutaneous injections of silver nanoparticles in solution and in liposomal form on hematological and biochemical parameters of blood of New Zealand White rabbits during hormonal treatment, fertilization and early embryonic development. The females treated by free silver nanoparticles and silver nanoparticles in liposomal form received silver at a dose of 10 µg/kg/day in 5 % glucose solution during 28 days. Blood sampling was done four times: the day before the compounds administration; on day 7 after the compounds administration; in the period after hormonal induction and fertilization and on the 14th day of pregnancy. Our results showed changes in some biochemical (lactate dehydrogenase activities, progesterone and estradiol concentration, malondialdehyde level, etc. and hematological (hematocrit, mean cell volume, mean corpuscular hemoglobin concentration, etc. parameters under the influence of hormonal treatment and pregnancy. The concentration of progesterone showed significantly higher values (P˂0.05 on GDs 1 in S group than in C group. The percentage of neutrophils was significantly higher in SG rabbits after 7 days of silver nanoparticles administration than that in the CG. There were no significant changes in red blood cells parameters, platelets, and activity of some ferments (ALP, AST, ALT, LDH, GGT between control and silver groups during the entire period of experiment. In conclusion, the hematological and biochemical values of blood obtained in the given study showed that free silver nanoparticles and silver nanoparticles in liposomal form in the investigated concentrations had no toxic effect on hormonal treatment, fertilization and early embryonic development in New Zealand White rabbits.

  5. National RF Test Facility as a multipurpose development tool

    International Nuclear Information System (INIS)

    McManamy, T.J.; Becraft, W.R.; Berry, L.A.


    Additions and modifications to the National RF Test Facility design have been made that (1) focus its use for technology development for future large systems in the ion cyclotron range of frequencies (ICRF), (2) expand its applicability to technology development in the electron cyclotron range of frequencies (ECRF) at 60 GHz, (3) provide a facility for ELMO Bumpy Torus (EBT) 60-GHz ring physics studies, and (4) permit engineering studies of steady-state plasma systems, including superconducting magnet performance, vacuum vessel heat flux removal, and microwave protection. The facility will continue to function as a test bed for generic technology developments for ICRF and the lower hybrid range of frequencies (LHRF). The upgraded facility is also suitable for mirror halo physics experiments

  6. Development of International Education at Suzuka National College of Technology (United States)

    Hanai, Takaaki; Kuwabara, Hirofumi; Kondo, Kunikazu; Minoura, Hirohito; Ito, Akira; Kondo, Kazuyuki; Ezaki, Hisakazu; Kawaguchi, Masashi; Inoue, Tetsuo; Lawson, Michael E.

    One of the educational goals of the Advanced Engineering Faculty of Suzuka National College of Technology is to instill in graduates the ability required to become an internationally engaged engineers. To help realize this goal a project oriented toward the development of an international internship or an international cooperative education (Co-op) system was planned and implemented for the past three years. In this paper the results of investigations concerning the present state of Co-op in the United States and Canada, a tentative international internship at a factory in the United States, and an educational program developed in cooperation with Georgian College in Canada are described. In cooperation with the Ohio State University, a newly developed distance interactive-learning system that enables us to simulate international internships is also proposed.

  7. Causes and consequences of fertility decline in China. (United States)

    Peng, P


    This article discusses the causes and consequences of fertility decline in China. Current policy focuses on promotion of deferred marriage and childbearing, fewer but healthier babies, and 1 child/couple. Some allowances are made for second children in rural areas. Fertility decline was augmented by socioeconomic change and an available means of birth control. In the 1990s, fertility declined below replacement level, and regional differences were further reduced. Average marriage age was 23 years in 1996. Spacing between first and second birth is 5 years. Higher parity births were 77% lower in 1996, than in 1990. Central authorities have held annual national forums on family planning since 1991. These forums stress balanced development of society, the economy, resources, the environment, and sustainable development. Program emphasis is on poverty areas in central and western China. Rapid fertility decline has reduced the pressure on population growth but created new problems for population aging. The percentage of elderly aged over 60 years will be over 10% in 2000 (130 million), 18.4% by 2025 (280 million), and 25% by 2050 (about 400 million). Population aging will have a strong impact on socioeconomic development during 2000-2050. China must pool state, family, and individual resources for the care of the elderly. The Social Security System will be improved under the 9th 5-Year Plan (1996-2000). Labor must be able to meet the needs of a market economy and technological development. Government is developing retraining and reemployment programs for the jobless.

  8. National heritage areas: examining organizational development and the role of the National Park Service as federal partner (United States)

    Susan Martin-Williams; Steven Selin


    Understanding the organizational development of National Heritage Areas (NHAs) and defining the National Park Service's (NPS) role within individual NHAs guided this qualitative study. Information gained during telephone interviews led to the development of an a priori model of the evolutionary stages of NHAs' organizational development and...

  9. Developing a national programme of flood risk management measures: Moldova

    Directory of Open Access Journals (Sweden)

    Ramsbottom David


    Full Text Available A Technical Assistance project funded by the European Investment Bank has been undertaken to develop a programme of flood risk management measures for Moldova that will address the main shortcomings in the present flood management system, and provide the basis for long-term improvement. Areas of significant flood risk were identified using national hydraulic and flood risk modelling, and flood hazard and flood risk maps were then prepared for these high risk areas. The flood risk was calculated using 12 indicators representing social, economic and environmental impacts of flooding. Indicator values were combined to provide overall estimates of flood risk. Strategic approaches to flood risk management were identified for each river basin using a multi-criteria analysis. Measures were then identified to achieve the strategic approaches. A programme of measures covering a 20-year period was developed together with a more detailed Short-Term Investment Plan covering the first seven years of the programme. Arrangements are now being made to implement the programme. The technical achievements of the project included national hydrological and hydraulic modelling covering 12,000 km of river, the development of 2-dimensional channel and floodplain hydraulic models from a range of topographic and bathymetric data, and an integrated flood risk assessment that takes account of both economic and non-monetary impacts.

  10. How to build additional soil fertility in organic cropping systems


    FertilCrop, Consortium


    FertilCrop aims at improving soil fertility using synergies provided by improved crop management techniques. The improvement of organic farming systems by building a higher level of soil fertility is important to develop more sustainable agroecosystems that safeguard soils and guarantee unrestrained crop growth. FertilCrop evaluates farming systems that efficiently build soil fertility based on field trials and farm networks in 13 European countries.

  11. Legislative framework affecting First Nations and resource development

    International Nuclear Information System (INIS)

    Maclean, M.


    In its Delgamuukw decision (released December 1997), the Supreme Court of Canada has given a clear direction to the Crown and First Nations to negotiate rather than litigate outstanding claims within the province of British Columbia. This paper describes the practical implications which the Delgamuukw decision will have for resource development on lands located within the traditional territories of Aboriginal people, reviews constitutional and jurisdictional issues, and discusses issues such as reserve lands in British Columbia, including the nature of reserve interest, tax considerations, the surrender of reserve lands, and provincial regulation on reserve lands

  12. Crafting New Business Strategy in Indonesia's Fertilizer Company ( Case Study in PT XYZ)


    Faswara, Lufan Nassya; Toha, Mohamad


    Fertilizer is the important product in Indonesia. The growth of Indonesia's is highly depending on the supply of fertilizer. PT XYZ is one of the national fertilizer company in Indonesia. PT XYZ is a subsidiary company of a State Owned Enterprise (BUMN) in Indonesia which engaged in fertilizer production and distribution. PT XYZ is the first fertilizer company in Indonesia with objectives to supply fertilizer products to Indonesian farmers. This time, PT XYZ is facing problems in achieving it...

  13. Marital moratorium and fertility control in China. (United States)

    Tien, H Y


    Abstract Since 1949, the issue of marital postponement has been extensively discussed in China. Unlike some other means of fertility control (e.g. abortion and oral contraception), marital postponement has been welcomed with the fewest misgivings. Lately, marital postponement has also been given renewed emphasis by those outside China who see a weak link between various current national family planning programmes based on improved technology and the goal of fertility reduction. One aim of this paper is to render a comprehensive account of the marital postponement programme in China in the course of the birth control campaign during the last two decades. The second objective is to discuss the lessons that may be learned from it, and its implications for the current fertility controversy in the United States. Four general conclusions emerge from a careful analysis of the available documents: (1) in China, proponents of delayed marriage were divided on the question of how to secure its general acceptance. One issue dividing them was whether or not China's Marriage Law of 1950 should be amended in order to achieve it. Those who favoured raising the minimum legal age disagreed on the details of the presumably needed change. There is enough evidence to suggest that medical personnel were the chief advocates of compulsory postponement of marriage. The government rejected this legalistic approach and, in so doing, agreed with Chen Ta (a noted demographer) and others who sought to achieve postponement of marriage through appropriate social and economic measures. (2) Decisions to delay matrimony in different socio-cultural settings are not necessarily identical sociological phenomena. In some societies, (e.g. the United States), they may amount to no more than a course of action that enables individuals involved to realize or develop alternate goals in life. In others (e.g. China), they are literally acts of rebellion. (3) The fertility policy dispute has been carried on in

  14. Non-fertile fuels development for plutonium and high-enriched uranium dispositioning in water cooled reactors

    Energy Technology Data Exchange (ETDEWEB)

    Olsen, C.S.


    As a result of dismantling the bomb, there is about 100 MT of excess weapons grade plutonium in the United States and about 150 MT in the Commonwealth of Independent States. In addition, there is another 1000 MT of plutonium in commercial spent fuel that may be used as degraded weapons material. This report discusses one means to disposition weapons grade plutonium is by irradiating the fuel in light water reactors (LWRs) using a non-fertile fuel based on plutonium dispersed in an oxide mixture of zirconia stabilized with calcia or yttria as a solid solution. Plutonium dispersed in a zirconia matrix offers the potential to achieve very high burnups while maintaining mechanical integrity.

  15. NAOJ's activities on Astronomy for Development: Aiding Astronomy Education in Developing Nations (United States)

    Sekiguchi, K.; Yoshida, F.


    We summarize NAOJ's efforts to promote astronomy in developing nations. The Office of International Relations, collaborations with the Office of Public Outreach at NAOJ and with the East Asia Core Observatories Association (EACOA), has engaged children, students and educators about astronomy development in the Asia-Pacific region. In particular, we introduce ``You are Galileo!`` project, which is a very well received astronomy education program for children. We also report on a continuing effort by the Japanese Government in support of astronomy programs in the developing nations.

  16. Fertility preservation during cancer treatment: clinical guidelines

    Directory of Open Access Journals (Sweden)

    Rodriguez-Wallberg KA


    Full Text Available Kenny A Rodriguez-Wallberg,1,2 Kutluk Oktay3,4 1Karolinska Institutet, Department of Clinical Science, Intervention and Technology, Division of Obstetrics and Gynecology, 2Reproductive Medicine, Karolinska University Hospital Huddinge, Stockholm, Sweden; 3Innovation Institute for Fertility Preservation, Rye and New York, 4Department of Obstetrics and Gynecology, New York Medical College, Valhalla, NY, USA Abstract: The majority of children, adolescents, and young adults diagnosed with cancer today will become long-term survivors. The threat to fertility that cancer treatments pose to young patients cannot be prevented in many cases, and thus research into methods for fertility preservation is developing, aiming at offering cancer patients the ability to have biologically related children in the future. This paper discusses the current status of fertility preservation methods when infertility risks are related to surgical oncologic treatments, radiation therapy, or chemotherapy. Several scientific groups and societies have developed consensus documents and guidelines for fertility preservation. Decisions about fertility and imminent potentially gonadotoxic therapies must be made rapidly. Timely and complete information on the impact of cancer treatment on fertility and fertility preservation options should be presented to all patients when a cancer treatment is planned. Keywords: fertility preservation, cancer, cryopreservation, ovarian tissue transplantation, fertility-sparing surgery, cancer survival, quality of life

  17. Biomass Accumulation, Photosynthetic Traits and Root Development of Cotton as Affected by Irrigation and Nitrogen-Fertilization

    Directory of Open Access Journals (Sweden)

    Zongkui Chen


    Full Text Available Limitations of soil water and nitrogen (N are factors which cause a substantial reduction in cotton (Gossypium hirsutum L. yield, especially in an arid environment. Suitable management decisions like irrigation method and nitrogen fertilization are the key yield improvement technologies in cotton production systems. Therefore, we hypothesized that optimal water-N supply can increase cotton plant biomass accumulation by maintaining leaf photosynthetic capacity and improving root growth. An outdoor polyvinyl chloride (PVC tube study was conducted to investigate the effects of two water-N application depths, i.e., 20 cm (H20 or 40 cm (H40 from soil surface and four water-N combinations [deficit irrigation (W55 and no N (N0 (W55N0, W55 and moderate N (N1 (W55N1, moderate irrigation (W75 and N0 (W75N0, W75N1] on the roots growth, leaf photosynthetic traits and dry mass accumulation of cotton crops. H20W55N1 combination increased total dry mass production by 29–82% and reproductive organs biomass by 47–101% compared with other counterparts. Root protective enzyme and nitrate reductase (NR activity, potential quantum yield of photosystem (PS II (Fv/Fm, PSII quantum yield in the light [Y(II] and electron transport rate of PSII were significantly higher in H20W55N1 prior to 82 days after emergence. Root NR activity and protective enzyme were significantly correlated with chlorophyll, Fv/Fm, Y(II and stomatal conductance. Hence, shallow irrigation (20 cm with moderate irrigation and N-fertilization application could increase cotton root NR activity and protective enzyme leading to enhance light capture and photochemical energy conversion of PSII before the full flowering stage. This enhanced photoassimilate to reproductive organs.

  18. Biomass Accumulation, Photosynthetic Traits and Root Development of Cotton as Affected by Irrigation and Nitrogen-Fertilization. (United States)

    Chen, Zongkui; Tao, Xianping; Khan, Aziz; Tan, Daniel K Y; Luo, Honghai


    Limitations of soil water and nitrogen (N) are factors which cause a substantial reduction in cotton ( Gossypium hirsutum L.) yield, especially in an arid environment. Suitable management decisions like irrigation method and nitrogen fertilization are the key yield improvement technologies in cotton production systems. Therefore, we hypothesized that optimal water-N supply can increase cotton plant biomass accumulation by maintaining leaf photosynthetic capacity and improving root growth. An outdoor polyvinyl chloride (PVC) tube study was conducted to investigate the effects of two water-N application depths, i.e., 20 cm (H 20 ) or 40 cm (H 40 ) from soil surface and four water-N combinations [deficit irrigation (W 55 ) and no N (N 0 ) (W 55 N 0 ), W 55 and moderate N (N 1 ) (W 55 N 1 ), moderate irrigation (W 75 ) and N 0 (W 75 N 0 ), W 75 N 1 ] on the roots growth, leaf photosynthetic traits and dry mass accumulation of cotton crops. H 20 W 55 N 1 combination increased total dry mass production by 29-82% and reproductive organs biomass by 47-101% compared with other counterparts. Root protective enzyme and nitrate reductase (NR) activity, potential quantum yield of photosystem (PS) II ( F v /F m ), PSII quantum yield in the light [Y(II)] and electron transport rate of PSII were significantly higher in H 20 W 55 N 1 prior to 82 days after emergence. Root NR activity and protective enzyme were significantly correlated with chlorophyll, F v /F m , Y(II) and stomatal conductance. Hence, shallow irrigation (20 cm) with moderate irrigation and N-fertilization application could increase cotton root NR activity and protective enzyme leading to enhance light capture and photochemical energy conversion of PSII before the full flowering stage. This enhanced photoassimilate to reproductive organs.

  19. Fidelity of test development process within a national science grant (United States)

    Brumfield, Teresa E.

    In 2002, a math-science partnership (MSP) program was initiated by a national science grant. The purpose of the MSP program was to promote the development, implementation, and sustainability of promising partnerships among institutions of higher education, K-12 schools and school systems, as well as other important stakeholders. One of the funded projects included a teacher-scientist collaborative that instituted a professional development system to prepare teachers to use inquiry-based instructional modules. The MSP program mandated evaluations of its funded projects. One of the teacher-scientist collaborative project's outcomes specifically focused on teacher and student science content and process skills. In order to provide annual evidence of progress and to measure the impact of the project's efforts, and because no appropriate science tests were available to measure improvements in content knowledge of participating teachers and their students, the project contracted for the development of science tests. This dissertation focused on the process of test development within an evaluation and examined planned (i.e., expected) and actual (i.e., observed) test development, specifically concentrating on the factors that affected the actual test development process. Planned test development was defined as the process of creating tests according to the well-established test development procedures recommended by the AERA/APA/NCME 1999 Standards for Educational and Psychological Testing. Actual test development was defined as the process of creating tests as it actually took place. Because case study provides an in-depth, longitudinal examination of an event (i.e., case) in a naturalistic setting, it was selected as the appropriate methodology to examine the difference between planned and actual test development. The case (or unit of analysis) was the test development task, a task that was bounded by the context in which it occurred---and over which this researcher had

  20. National Energy Audit Tool for Multifamily Buildings Development Plan

    Energy Technology Data Exchange (ETDEWEB)

    Malhotra, Mini [ORNL; MacDonald, Michael [Sentech, Inc.; Accawi, Gina K [ORNL; New, Joshua Ryan [ORNL; Im, Piljae [ORNL


    The U.S. Department of Energy's (DOE's) Weatherization Assistance Program (WAP) enables low-income families to reduce their energy costs by providing funds to make their homes more energy efficient. In addition, the program funds Weatherization Training and Technical Assistance (T and TA) activities to support a range of program operations. These activities include measuring and documenting performance, monitoring programs, promoting advanced techniques and collaborations to further improve program effectiveness, and training, including developing tools and information resources. The T and TA plan outlines the tasks, activities, and milestones to support the weatherization network with the program implementation ramp up efforts. Weatherization of multifamily buildings has been recognized as an effective way to ramp up weatherization efforts. To support this effort, the 2009 National Weatherization T and TA plan includes the task of expanding the functionality of the Weatherization Assistant, a DOE-sponsored family of energy audit computer programs, to perform audits for large and small multifamily buildings This report describes the planning effort for a new multifamily energy audit tool for DOE's WAP. The functionality of the Weatherization Assistant is being expanded to also perform energy audits of small multifamily and large multifamily buildings. The process covers an assessment of needs that includes input from national experts during two national Web conferences. The assessment of needs is then translated into capability and performance descriptions for the proposed new multifamily energy audit, with some description of what might or should be provided in the new tool. The assessment of needs is combined with our best judgment to lay out a strategy for development of the multifamily tool that proceeds in stages, with features of an initial tool (version 1) and a more capable version 2 handled with currently available resources. Additional

  1. The Topical Factors of Development of the National Competitive Advantages

    Directory of Open Access Journals (Sweden)

    Kolomiets Ganna M.


    Full Text Available The article considers the qualitative changes of the national competitive advantages as derivatives of the evolution of technological modes in the global business environment; the role of both the formal and the informal institutions in their development and implementation has been analyzed. With this in mind, topical in the development of competitive advantages will be improving the formal institutions in conjunction with the informal: recognition and use of the positive potential of the national values and attitudes. High adaptatibility towards turbulence of the economic environment, desire and capability to master new knowledge, technologies, fulfill one’s own abilities in the native country, should define the focus and content of transformations of the formal institutions. Results of the analysis show that nowadays a value shift is going on, attitudes are being changed, which suggests that there’s a necessity to understand that disposition of power institutions, mistrust to authorities can significantly slow down transformations in the direction of «competitive advantages – competitiveness»

  2. Status of National Minorities in Developed European Countries

    Directory of Open Access Journals (Sweden)

    Nada Raduški


    Full Text Available Contemporary geopolitical changes, interethnic conflicts and clashes, and the connection between minority and territorial problems considerably influence the quality of inter-state relations and the preservation of global peace and security. National problems and ethnic confrontations found a firm ground on the territory of the Balkans, although they are known in democratic West-European countries as well, despite high standards in respecting human rights. However, even though they deserve special attention due to their seriousness, they remain exclusively under those countries’ jurisdiction, as opposed to countries in transition that are in the focus of interest and intervention of the international community. In developed countries, the method of regulating the minority question greatly depends on the position of that country on the world economic and political scene, apart from numerous historical and political factors. In each of these countries, there are specific models of coexistence of majority and minority population conditioned by numerous factors, so there does not exist a universal model that would be valid for all countries. Respecting basic human rights, as well as national minority protection, represent the basic factors of the stability, and democratic and socio-economic development of every country.

  3. [Health in the post-2015 United Nations Development Agenda]. (United States)

    Buss, Paulo Marchiori; Magalhães, Danielly de Paiva; Setti, Andréia Faraoni Freitas; Gallo, Edmundo; Franco Netto, Francisco de Abreu; Machado, Jorge Mesquita Huet; Buss, Daniel Forsin


    This paper evaluates health as a Sustainable Development Goal (SDG) in the context of the Post-2015 Development Agenda, between 2012 and 2014. Health was part of the debate since the Millennium Summit and the MDGs (2000), and it also appears in the documents discussing the Post-2015 Agenda, from the Rio+20 to the Open Working Group (OWG), whose report was submitted to the General Assembly of the United Nations (UNGA) 2014-2015, and in the Global Consultation on Health and the High-Level Panel of Eminent Persons reports. The Authors concluded that the treatment of health in all these documents is uniform. They point out that the scope of the health-related SDG is very comprehensive, but its targets are conceptually fragmented and reduced. They advocate their change as to include not only the idea of social determinants of health, but also targets in the field of public health, which were not included in the proposal of the OWG. They also warn that the global and national governance systems need to be reformed and advocate more participation of the civil society, which can influence diplomacy, which, in turn, will be responsible for the agreement signed at the UNGA in 2015.

  4. The United Nations and Climate Change: Legal and Policy Developments (United States)

    Bunn, Isabella D.


    The Secretary-General of the United Nations, Ban Ki-moon, has declared that climate change is "the defining challenge of our times." Climate change trends indicate increasingly severe negative impacts on the majority of countries, with disproportionate effects on poor and vulnerable populations. The scientific reports of the Intergovernmental Panel on Climate Change (IPCC), as well as the negotiations under the UN Framework Convention on Climate Change (UNFCCC), have placed the issue on the forefront of the international agenda. This article examines how climate change is shaping legal and policy developments in five key areas of UN responsibility: international law, humanitarian affairs, human rights, development, and peace and security. It concludes with some observations about high-level efforts to coordinate the response of multilateral institutions, the changing stance of the US government, and the role of environmental protection in addressing the current global economic crisis.

  5. National Youth Service Day: A Youth Development Strategy

    Directory of Open Access Journals (Sweden)

    Silvia Blitzer Golombek


    Full Text Available A growing number of studies show connections between youth participation in service and service-learning opportunities and positive behavior outcomes. Building on this data, the article presents National Youth Service Day (NYSD as a program that can be incorporated into ongoing activities to enhance youth development goals. The paper describes the program’s components– building a network of support organizations, offering project planning grants, providing service-learning materials, and developing a media and advocacy campaign. Examples of NYSD projects show how project planners are using the program to learn and practice academic and non-academic skills. A review of evaluations to date indicates the program is annually increasing its output measures. Participants’ responses show that the program is also contributing to positive behavioral changes, in particular related to young people’s increasing awareness about specific community issues and their own competency in addressing them.

  6. The DEVELOP National Program's Strategy for Communicating Applied Science Outcomes (United States)

    Childs-Gleason, L. M.; Ross, K. W.; Crepps, G.; Favors, J.; Kelley, C.; Miller, T. N.; Allsbrook, K. N.; Rogers, L.; Ruiz, M. L.


    NASA's DEVELOP National Program conducts rapid feasibility projects that enable the future workforce and current decision makers to collaborate and build capacity to use Earth science data to enhance environmental management and policy. The program communicates its results and applications to a broad spectrum of audiences through a variety of methods: "virtual poster sessions" that engage the general public through short project videos and interactive dialogue periods, a "Campus Ambassador Corps" that communicates about the program and its projects to academia, scientific and policy conference presentations, community engagement activities and end-of-project presentations, project "hand-offs" providing results and tools to project partners, traditional publications (both gray literature and peer-reviewed), an interactive website project gallery, targeted brochures, and through multiple social media venues and campaigns. This presentation will describe the various methods employed by DEVELOP to communicate the program's scientific outputs, target audiences, general statistics, community response and best practices.

  7. National Identity and Distinctiveness: Developing a Common Identity ...

    African Journals Online (AJOL)

    The aim of this article is to argue that distinctiveness is at the core of national identity and nationalism. After a brief assessment of mainstream theories of nationalism with an emphasis on civic and primordialist approaches, the following question is posed: How important is the association of national identity to the stability of ...

  8. Development of clonal matrices of australian red cedar in different substrates under fertilizer doses Desenvolvimento de matrizes clonais de cedro Australiano em diferentes substratos sob doses de fertilizantes

    Directory of Open Access Journals (Sweden)

    Bruno Peres Benatti


    Full Text Available In order to evaluate fertilizers doses in different substrates for growth and development of clonal matrices of Australian Red Cedar [Toona ciliata var. australis (F. Muell. Bahadur], an experiment was conducted in a greenhouse. Five substrates were evaluate, with proportions by volume, the first consisting of 100% of Multiplant florestal®, the second of 50% vermiculite, 20% carbonized rice hulls, 20% soil and 10% coconut fiber, the third with 50% soil and 50% sand, the fourth was composed by 50% Multiplant florestal®, 10% soil and 40% coconut fiber and the fifth with 65% of Multiplant florestal®, 25% vermiculite and 10% carbonized rice hulls. The fertilizers doses applied were 0.0; 0.3; 0.6; 1.2; 2.4 of fertilization suggested by Malavolta (1980 for vases. The characteristics evaluated were: collar diameter of the matrices, production of dry mater by shoots, root system and total and accumulation of nutrients by shoot at the end of the experimental period of 150 days. The Australian Red Cedar plants have high nutritional requirements, as showed by the better development obtained with higher fertilizer doses than those suggested by Malavolta (1980. The substrate three provided the worst development to clonal matrices while the substrates 1, 4 and 5 provided the best environment for the development considering all the fertilizer doses and all variables.Com o objetivo de avaliar diferentes substratos com taxas de fertilizantes para o crescimento e desenvolvimento de matrizes clonais de cedro australiano [Toona ciliata var. australis (F. Muell. Bahadur], foi realizado um experimento em casa de vegetação. Foram avaliados cinco substratos, com as proporções em volume, sendo o primeiro composto por 100% Multiplant florestal®, o segundo de 50% Vermiculita, 20% casca de arroz carbonizada, 20% terra e 10% fibra de coco, o terceiro com 50% terra e 50% areia, o quarto com proporção de 50% Multiplant florestal®, 10% terra e 40% de fibra de coco e

  9. Cancer and fertility : strategies to preserve fertility

    NARCIS (Netherlands)

    Diedrich, K.; Fauser, B. C. J. M.; Devroey, P.

    Fertility preservation is a key component of cancer management in young people. The Fourth Evian Annual Reproduction Workshop Meeting was held in April 2009 to discuss cancer and fertility in young adults. Specialists in oncology, assisted reproduction, embryology and clinical genetics presented

  10. Human resource development, National Nuclear Energy Agency, Indonesia

    International Nuclear Information System (INIS)



    The development of an adequate national education and training infrastructure is the solution to solve the demand for qualified manpower to meet the national requirements of any nuclear program. Education and training activities were initiated in the year of 1981 with the forming of the Education and Training Center (ETC). The aging of manpower and the government policy on zero growth results in the discontinuity of knowledge transfer within the organization, and may be in the future of nuclear technology implementation. Since 1981 ETC has contributed to the training of its employees and industrial personnel through 800 training and involving around eleven thousand participants. Education and Training Center of BATAN accredited by BAPETEN as the nuclear training institutes for Radiation Protection Officer Certification, and in process of accreditation by National Accreditation Board as training institute for Non Destructive Test Personnel Certification. Annually ETC conduct 5 RPO training and 5 NDT Level I and 3 NDT Level II training. As shown in attached Table, there are at least 2999 RPO in Indonesia responsible for the safe operation of 4843 radioactive sources and 3741 radiation sources. Among the approximately 3700 employees of BATAN, national infrastructure has contributed to the education of 911 S1-graduates program, 24 master degree and 21 doctoral degree programs, while 46 bachelors degree, 201 master degree and 98 doctoral degree were taken overseas. Human resources have been identified on many occasions as being one of the most important elements for engaging in various types of nuclear applications. Major efforts must be directed towards attracting sufficient number of bright and interested students to the nuclear field for both current and future nuclear technology utilization. Therefore, it is necessary to transfer knowledge and know-how to the young generation for the sustainable development of nuclear science and technology. Courses in nuclear


    Directory of Open Access Journals (Sweden)

    Adina Nicoleta CANDREA


    Full Text Available Sustainable development means “Think global but act local” (David Brower the founder of the nongovernmental organization Friends of the Earth 1969. Lasting tourism is considered in most of the cases a tourism manner, but all the touristy activities should be durable and bring economic and social benefices to local communities and to encourage the conservation with nature. On the international level, many destinations have chosen to promote ecotourism in order to improve the problems regarding the environment, and for to encouraging the area development. This kind of tourism encourages the responsible behavior of the tourists, local culture and appreciation for the traditional way of living, the conservation of some habitats and ecosystems and brings ways of sustainable development for local communities situated in natural areas with infrastructure problems. Ecotourism is the most recommended one in the protected areas, because the local resources can be advantageous used without causing the degradation of the area. The Retezat National Park is the first park founded in Romania and has a remarkable tourism potential, insufficiently exploited and many times deteriorated by applying an inadequate tourism to a protected area. Ecotourism can bring socio-economic development for the communities round the park, natural and cultural potential capitalization in the area and can be a catalyzing for a sustainable development of tourism and nature conservation. For the development of this kind of tourism the administration efforts of the park, authorities and local communities should be directed to sustainable forms of development and the adjustment of touristy infrastructure of ecotourism requirements.

  12. Desenvolvimento e testes de uma semeadora-adubadora modular para pequenas propriedades rurais Development and test of a modular seeder - fertilizer for small countryside properties

    Directory of Open Access Journals (Sweden)

    Lucas Arend


    Full Text Available O trabalho apresenta o desenvolvimento e testes de campo de equipamento agrícola modular. Para o desenvolvimento do equipamento, foi utilizada metodologia de projeto para sistemas modulares. O objetivo principal foi desenvolver um sistema modular que contribuísse para melhorar o atual quadro de mecanização agrícola da pequena propriedade rural, enfocando alguns dos equipamentos destinados às atividades conservacionistas de cultivo. Por ser modular, o equipamento atende às funções de semear-adubar, escarificar e sulcar o solo. Para a função semear-adubar, podem ser usados cinzéis e disco duplo para a semeadura; já para as funções de escarificação e sulcagem, podem ser usadas ferramentas específicas, facilmente intercambiadas em um chassi tubular principal. Os resultados para solo argiloso (Typic Oxisols, com umidade em torno de 20,5% e massa seca de 11,5 t ha-1 para a variante semeadora-adubadora com duplo cinzel, foram satisfatórios com relação aos parâmetros de patinagem das rodas motoras, regularidade de distribuição em profundidade, cobertura das sementes, distribuição longitudinal das sementes e emergência de plantas.This work presents the development and field tests of a modular agricultural implement. A Modular Design Product methodology was used for the implement development, and the main objective was the development of a modular system to improve the actual situation of mechanization on small countryside properties. The development focus was kept on some implements for conservative cultivation. For its modularity, the implement developed attained the functions of seeding - fertilizing, scarification and furrowing the soil. For the function of seeding-fertilizing can be used either narrow chisels or double disc, for the furrowing function a specific tool can be used. The main tubular chassis allowed an easily interchangeability between both functions (seed-season and furrow-season. The results for Typical

  13. Developing a provisional and national renal disease registry for Iran

    Directory of Open Access Journals (Sweden)

    Sima Ajami


    Full Text Available Background: Disease registry is a database that includes information about people suffering a special kind of disease. The aim of this study was to first identify and compare the National Renal Disease Registry (NRDR characteristics in some countries with Iran; and second, develop a provisional and NRDR for Iran. Materials and Methods: Retrieval of data of the NRDR was performed by scholars responsible in related agencies, including the Ministry of Health and Medical Education, Renal Disease charity, and data registries in the United States, United Kingdom, Malaysia, and Iran. This research was applied, and the study was descriptive-comparative. The study population consisted of the NRDR in selected countries in which data were collected by forms that were designed according to the study objectives. Sources of data were researchers, articles, books, journals, databases, websites, related documents, and people who are active in this regard, and related agencies, including the Ministry of Health and Medical Education, and patient support charity. The researchers collected data for each country based on the study objectives and then put them in comparative tables. Data were analyzed by descriptive, comparative, and theoretical methods. Results: Most of the renal transplant teams report their own results as a single center experiences. America and Britain have a preeminent national registry of renal disease compared to other countries. Conclusion: Given that control, prevention, and treatment of chronic renal diseases incur high expenses and the disease is one of leading mortality factors in Iran and across the world and since national registry system for chronic renal diseases can provide better tools and strategies to manage and evaluate patients′ characteristics as well as risk factors which eventually leads to making better decisions.

  14. Recommendations to improve the National Development Plan for Health. (United States)

    de Jager, Pieter; Hofman, Karen; Khan, Taskeen; Volmink, Heinrich; Jina, Ruxana


    In November 2011, a draft National Development Plan (NDP) was released that addresses two of South Africa's major challenges: poverty and inequity. Health and economic development are interdependent, presenting an important opportunity through the NDP to integrate health within goals of broader socio-economic development. Reviewing the NDP identified gaps based on evidence and the epidemiological risk profile of South Africa. Recommendations to improve the NDP and to deal with poverty and inequity should focus on prevention and addressing the social determinants of health, including: (i) a multisectoral approach to establish a comprehensive early childhood development programme; (ii) fiscal and legislative policies to bolster efforts to reduce the burden of non-communicable diseases; (iii) promoting and maintaining a healthy workforce; (iv) and promoting a culture of evidence-based priority setting. Achieving the goal of 'a long and healthy life for all South Africans' will require healthy public policies, well functioning institutional and physical infrastructure, social solidarity, and an active and conscientious civil society.

  15. Outcomes from a national multispecialty palliative care curriculum development project. (United States)

    Weissman, David E; Ambuel, Bruce; von Gunten, Charles F; Block, Susan; Warm, Eric; Hallenbeck, James; Milch, Robert; Brasel, Karen; Mullan, Patricia B


    In 1998 we completed a successful regional pilot project in palliative care curriculum development among 32 internal medicine residency programs recruited from the mid-western United States. Between 1999 and 2004 this project was expanded to include 358 U.S. programs, from four specialties, based on new training requirements in internal medicine, family medicine, neurology, and general surgery. To assess the 1-year outcomes from residency programs participating in a national multispecialty palliative care curriculum development project. Outcome data obtained from residency programs' responses to a structured progress report 12 months after enrolling in the project and from published residency project reports. Three hundred fifty-eight residency programs, representing 27% of all eligible training programs in the four specialties, participated in the project. Outcome data was available from 224 residencies (63%). Most programs started new teaching in pain, non-pain symptom management, and communication skills. More than 50% of programs integrated palliative care topics within established institutional grand rounds, morbidity/mortality conferences or morning report. More than 70% of internal medicine and family practice programs began new direct patient care training opportunities utilizing hospital-based palliative care or hospice programs. New faculty development initiatives and use of quality improvement projects to drive curriculum change were reported in less than 50% of programs. Focused short-term instruction in palliative care curriculum development, in a diverse group of residency programs, is feasible and associated with significant curriculum change.

  16. Enhancing Soil Fertility through Intercropping, Inoculation and Fertilizer

    International Nuclear Information System (INIS)

    Ullah, M. A.; Hussain, N.; Schmeisky, H.; Rasheed, M.


    The present study was conducted to investigate the effects of intercropping grass (Panicum maximum) and legumes (Vicia sativa and cowpeas) alone or coupled with inoculation or fertilizer on soil fertility. The study comprised of two field experiments conducted under rain fed conditions for two years (June 2005 to September 2007) at National Agriculture Research Centre, Islamabad, Pakistan. In one experiment intercropping (33, 50 and 67%) of grass and legumes alone as well as coupled with seed inoculation were studied while, same set of treatments was combined with fertilizer application at the rates of 25, 75 and 50 kg/ha (N, P/sub 2/O/sub 5/ and K/sub 2/O) in the second experiment. Total soil N increased by 0.008 percent due to symbiotic fixation in addition to plant uptake under best treatment when compared with grass alone while, soil organic matter increased by 0.19 percent. After crop harvest soil N content was determined to be higher in all the treatments of the experiment compared with growing grass alone. Legumes caused rhizobial N fixation that caused an increase in soil N. Similarly, intercropping and inoculation increased this soil characteristic that was found to be non-significant in the first crop but later on became significant, especially when intercropping of grass with legumes after seed inoculation was investigated or fertilizer was supplemented to the crops. Thus, not only grass used the symbiotically fixed N by companion legumes but also enhanced the soil N content. The effect of fertilizer was not measurable statistically in case of soil organic matter. This parameter, in general, was not affected significantly when assessed after first crop harvest. Nevertheless, legumes alone or intercropped within grass increased this important soil constituent. Inoculation proved further beneficial in this regard but combination of intercropping (especially 67%) either with seed inoculation or application of fertilizer was found as the best technique for

  17. Development of Analytical methods for the evaluation of the impact of phosphate fertilizer industry on marine environment

    International Nuclear Information System (INIS)

    Aoun, M.


    Phosphate industries are considered an important potential source of natural radionuclides and heavy metals contamination in the environment. The objective of this work was to assess the marine environmental metallic and radiological pollution and the toxicological impact caused by a large production plant of phosphate fertilizer located on the eastern coast of the Mediterranean Sea, 40 km north of the capital of Lebanon: Beirut. Since 1957 this industry has been producing a large set of phosphate based fertilizers. Phosphogypsum, by-product resulting in the industrial procedure, is released directly in the marine environment. Natural radionuclides (238U, 235U, 226Ra, 232Th, 210Po, 210Pb, and 40K) and anthropogenic 137Cs were measured by alpha and gamma spectrometry in seawater, sediment, coastal sediment and biota. An alpha spectrometer with a passive ion implanted silicon detector was used for the determination of 238U, 234Uin sea water and 210Poin biota samples. 238U, 235U, 232Th, 226Ra,210Pb,137Cs and 40Kin biota and sediments were analyzed by a gamma spectrometer from Canberra, equipped with an extended range low-level coaxial high purity germanium detector with beryllium window.In addition, the radiation exposure of the population surrounding the industrial plant and the internal exposure and potential risks to human due to 210Poand 210Pbassociated with the consumption of fish have been estimated. The internal exposure due to the consumption of fish is important from the radioecology and radioprotection perspectives, and the data for most species studied, are reported for the first time in Lebanon. A multi-elemental method for simultaneous determination of trace elements in seaweeds based on the use of the new approach of collision reaction interface for the ICP-MS determination was optimized. The performance characteristics including linearity, limits of detection and quantification, repeatability, accuracy and truenesswere evaluated. Investigations on the

  18. Male Fertility Issues (United States)

    Fertility issues are common in boys and men getting cancer treatment. Fertility preservation options include sperm banking, testicular shielding, testicular sperm extraction (TESE), and testicular tissue freezing. Support and clinical trials are listed.

  19. Protect Your Fertility (United States)

    ... brochure briefly explains how such behaviors put your fertility at risk. Decisions and choices that you make ... your teens and early twenties can affect your fertility for years to come. This prevention guide was ...

  20. TCRC Fertility Page (United States)

    The Testicular Cancer Resource Center The TCRC Fertility Page Testicular Cancer and fertility are interrelated in numerous ways. TC usually affects young men still in the process of having a family. ...

  1. Fertility Treatments for Females (United States)

    ... for Females Share Facebook Twitter Pinterest Email Print Fertility Treatments for Females Once a woman is diagnosed ... The presence or absence of male factor infertility Fertility treatments are most likely to benefit women whose ...

  2. Infertility and Fertility (United States)

    ... Facebook Twitter Pinterest Email Print About Infertility and Fertility "Infertility" is a term that describes when a ... infertility and recurrent pregnancy loss: A committee opinion. Fertility and Sterility, 99 (1), 63. American Society for ...

  3. Child Costs and the Causal Effect of Fertility on Female Labor Supply: An investigation for Indonesia 1993-2008


    Priebe, Jan


    Over the last two decades Indonesia has experienced a significant decline in fertility rates and substantial increases in the level of education of women. Despite this development female labor force participation rates have remained roughly constant throughout this period. This paper explores the causes for the seeming unresponsiveness of female labor supply to changes in fertility. The empirical analysis is performed using annual data from the national household survey Susenas for the period...

  4. Desenvolvimento do feijoeiro sob o uso de biofertilizante e adubação mineral Development of bean with the use of mineral fertilization and biofertilizer

    Directory of Open Access Journals (Sweden)

    João A Galbiatti


    Full Text Available A produção intensiva de alimentos exige manejo adequado do solo para garantir a produtividade e a sustentabilidade ambiental. Uma das alternativas é a utilização de resíduos orgânicos no desenvolvimento das culturas, diminuindo a dependência de adubos minerais. Com o objetivo de avaliar o desenvolvimento da cultura de feijão (Phaseolus vulgaris L., utilizando biofertilizante e adubação mineral, conduziu-se o experimento com seis tratamentos dispostos ao acaso, em esquema fatorial, em quatro blocos, com parcelas de 8,0 x 5,0 m. Os tratamentos sob solo cultivado com a cultura de feijão caracterizaram-se como: com e sem biofertilizante (CB e SB, respectivamente e para a adubação mineral foram utilizadas a dose recomendada no plantio, ½ dose de adubação e sem adubação mineral (AM, 1/2AM, SAM. Adotaram-se práticas culturais convencionais para o preparo inicial do solo, e em seguida foi efetuada a aplicação de biofertilizante de origem bovina na dosagem de 100 m³ ha-1, com antecedência de três meses da semeadura. Foram avaliados os parâmetros massa da matéria seca acumulada na parte aérea da planta, área foliar e produtividade da cultura. Os resultados mostraram semelhanças entre as características analisadas, obtendo-se melhor desenvolvimento à cultura que recebeu biofertilizante.The intensive production requires appropriate management of soil to ensure the productivity and to avoid deterioration. One of the alternatives in improving the environmental quality in agriculture is the use of organic waste in the development of crops, reducing the dependence on mineral fertilizers. To evaluate the development of beans (Phaseolus vulgaris using mineral fertilizer and biofertilizer, the experiment was conducted with six treatments randomly distributed in four blocks, with plots of 8.0 x 5.0 meters. The experimentation treatments were characterized as: with and without biofertilizer (WB e WOB, respectively, and for mineral

  5. Teen Fertility and Gender Inequality in Education: A Contextual Hypothesis

    Directory of Open Access Journals (Sweden)

    C. Shannon Stokes


    Full Text Available Previous studies in developed countries have found a micro-level association between teenage fertility and girls' educational attainment but researchers still debate the policy implications of these associations. First, are these associations causal? Second, are they substantively important enough, at the macro-level, to warrant policy attention? In other words, how much would policy efforts to reduce unintended pregnancy among teens pay off in terms of narrowing national gender gaps in educational attainment? Third, under what contexts are these payoffs likely to be important? This paper focuses on the latter two questions. We begin by proposing a contextual hypothesis to explain cross-national variation in the gender-equity payoffs from reducing unintended teen fertility. We then test this hypothesis, using DHS data from 38 countries.

  6. UPF2, a nonsense-mediated mRNA decay factor, is required for prepubertal Sertoli cell development and male fertility by ensuring fidelity of the transcriptome

    DEFF Research Database (Denmark)

    Bao, Jianqiang; Tang, Chong; Yuan, Shuiqiao


    Nonsense-mediated mRNA decay (NMD) represents a highly conserved RNA surveillance mechanism through which mRNA transcripts bearing premature termination codons (PTCs) are selectively degraded to maintain transcriptomic fidelity in the cell. Numerous in vitro studies have demonstrated the importance...... SCs and germ cells during prepubertal testicular development. RNA-Seq and bioinformatic analyses revealed impaired transcriptomic homeostasis in SC-specific Upf2 knockout testes, characterized by an accumulation of PTC-containing transcripts and the transcriptome-wide dysregulation of genes encoding...... splicing factors and key proteins essential for SC fate control. Our data demonstrate an essential role of UPF2-mediated NMD in prepubertal SC development and male fertility....

  7. The quality of sample surveys in a developing nation

    Directory of Open Access Journals (Sweden)

    Paul A Bourne


    Full Text Available Paul A Bourne1, Christopher AD Charles2,3, Neva South-Bourne4, Chloe Morris1, Denise Eldemire-Shearer1, Maureen D Kerr-Campbell51Department of Community Health and Psychiatry, Faculty of Medical Sciences, University of the West Indies, Mona, Kingston, Jamaica; 2King Graduate School, Monroe College, Bronx, New York, USA; 3Center for Victim Support, Harlem Hospital Center, New York, USA; 4Research assistant for Paul A Bourne; 5Systems Development Unit, Main Library, Faculty of Humanities and Education, University of the West Indies, Mona, Kingston, JamaicaBackground: In Jamaica, population census began in 1844, and many intercensal ratios obtained from the census data showed that there is a general high degree of accuracy of the data. However, statistics from the Jamaican Ministry of Health showed that there are inaccuracies in health data collected from males using sample surveys.Objectives: The objectives of the present research are to 1 investigate the accuracy of a national sample survey, 2 explore the feasibility and quality of using a subnational sample survey to represent a national survey, 3 aid other scholars in understanding the probability of using national sample surveys and subnational sample surveys, 4 assess older men’s ­evaluation of their health status, and 5 determine whether dichotomization changes self-evaluated health status.Methods: For the current study, the data used in the analysis were originally collected from 2 different sources: 1 the Jamaica Survey of Living Conditions (JSLC and 2 Survey of Older Men (SOM. Cross validation of self-evaluated data of men in Jamaica was done with comparable samples of the complete JSLC data and the SOM data, where men older than 55 years were selected from each sample.Results: In study 1, 50.2% of respondents indicated at least good self-evaluated health status compared with 74.0% in study 2. Statistical associations were found between health status and survey sample (Χ2 [df = 5

  8. Development of H- sources at Brookhaven National Laboratory

    International Nuclear Information System (INIS)

    Prelec, K.


    Negative hydrogen ion sources have been developed at Brookhaven National Laboratory for several years, with the initial goal to design a source for accelerator applications and later on to design a large unit for applications in neutral beam injectors of magnetic fusion devices. Three types of sources were investigated, a hollow discharge duoplasmatron yielding H - currents up to 60 mA, a Penning source yielding H - currents up to 440 mA, and a magnetron source yielding H - currents up to 1 A. All sources operate with a mixture of hydrogen gas and cesium vapors, and H - ions are most likely produced on cesium covered electrode surfaces. A larger model of a Penning/magnetron source was constructed and will be tested soon; it incorporates among other new features a system for the cooling of the cathode

  9. Analysis of collection development at the National Library of Medicine. (United States)

    Craig, D F; Strain, P M


    This paper reports the major findings of a study of collection development activities at the National Library of Medicine (NLM) from 1965 to 1977. The CATLINE file was the source of the data; analyses were performed on classification number, date of entry, and language. An overview analysis of the data base is presented for major subject and form classes. An in-depth subject analysis of the monograph collection was performed using the NLM call number. An analysis by date of entry revealed that the subject content of CATLINE has varied only slightly over the years; the most notable change was a recent decline in the related and peripheral subject areas. The language analysis indicated that 83% of the data base consisted of works published in English, German, Russian, and French. Throughput processing time was measured for English language monographs for selected years. PMID:6988025

  10. The development of a successful non-university-based ambulatory in vitro fertilization/embryo transfer program: phase I. (United States)

    Sher, G; Knutzen, V; Stratton, C J; Montakhab, M M; Allenson, S G; Mayville, J; Rubenstein, J A; Glass, M J; Bilach, S M


    Most of the current in vitro fertilization and embryo transfer (IVF-ET) programs are university-based. The establishment of a successful ambulatory IVF program in association with a busy, two-man general obstetrics-gynecologic practice is described. Seventy-one infertile couples were screened between February 1 and October 15, 1983. Forty-three couples were judged eligible for IVF-ET. Forty-three women underwent a single attempt at ET. The first 13 of these women underwent controlled ovarian hyperstimulation (COH) with 150 mg clomiphene citrate and human chorionic gonadotropin (hCG), and the remaining 30 underwent COH with human menopausal gonadotropin (hMG) and hCG. One of the 13 patients who underwent COH with clomiphene citrate conceived but subsequently miscarried early in the first trimester, for an 8% pregnancy rate. There were 12 pregnancies among the 30 patients who received hMG and hCG, for a 40% pregnancy rate. Only three of these pregnancies miscarried in the early first trimester, and three of the nine viable pregnancies are twin gestations. The possible factors responsible for the high pregnancy rate with IVF-ET, using COH with hMG and hCG, are discussed, and the feasibility of its performance in a well-controlled, non-university program is demonstrated.

  11. Comparative transcript profiling of a male sterile cybrid pummelo and its fertile type revealed altered gene expression related to flower development.

    Directory of Open Access Journals (Sweden)

    Bei-Bei Zheng

    Full Text Available Male sterile and seedless characters are highly desired for citrus cultivar improvement. In our breeding program, a male sterile cybrid pummelo, which could be considered as a variant of male fertile pummelo, was produced by protoplast fusion. Herein, ecotopic stamen primordia initiation and development were detected in this male sterile cybrid pummelo. Histological studies revealed that the cybrid showed reduced petal development in size and width, and retarded stamen primordia development. Additionally, disorganized cell proliferation was also detected in stamen-like structures (fused to petals and/or carpel. To gain new insight into the underlying mechanism, we compared, by RNA-Seq analysis, the nuclear gene expression profiles of floral buds of the cybrid with that of fertile pummelo. Gene expression profiles which identified a large number of differentially expressed genes (DEGs between the two lines were captured at both petal primordia and stamen primordia distinguishable stages. For example, nuclear genes involved in nucleic acid binding and response to hormone synthesis and metabolism, genes required for floral bud identification and expressed in particular floral whorls. Furthermore, in accordance with flower morphology of the cybrid, expression of PISTILLATA (PI was reduced in stamen-like structures, even though it was restricted to correct floral whorls. Down-regulated expression of APETALA3 (AP3 coincided with that of PI. These finding indicated that, due to their whorl specific effects in flower development, citrus class-B MADS-box genes likely constituted 'perfect targets' for CMS retrograde signaling, and that dysfunctional mitochondria seemed to cause male sterile phenotype in the cybrid pummelo.

  12. [Intergenerational fertility changes]. (United States)

    Smolinski, Z


    Intergenerational changes in fertility in Poland are analyzed using data from a 1977 sample survey of 38,600 women. The author notes that total fertility declined from 4.4 to 2.5 within the space of two generations. An analysis of fertility is presented by various characteristics of females, including age group, education, duration of marriage, and economic status.

  13. Nanocomposites for controlled release of nitrogen fertilizer

    International Nuclear Information System (INIS)

    Silva, Viviane J.M. da; Visconte, Leila L.Y.; Nascimento, Regina Sandra V.


    The study aimed at the development of nano structured materials capable of reducing the rate of release of nitrogen in the soil from an agricultural nitrogen fertilizer. Four different systems of polymer composites were prepared: (1) montmorillonite clay/fertilizer, (2) montmorillonite clay/thermoplastic starch and fertilizer, (3) montmorillonite clay/fertilizer, thermoplastic starch and low-density polyethylene (LDPE) and also (4) montmorillonite clay/fertilizer, thermoplastic starch and polycaprolactone. It was confirmed the formation of nano structured materials by elemental analysis (CHN) and X-ray diffraction (XRD). The kinetics of nitrogen release was detected by enzymatic colorimetric analysis and spectroscopy in the ultraviolet/visible. The results showed that all materials evaluated were able to reduce the rate of release of nitrogen in the fertilizers. (author)

  14. Radioisotope research and development at Los Alamos National Laboratory

    International Nuclear Information System (INIS)

    Peterson, E.J.


    Throughout its fifty year history, Los Alamos National Laboratory has conducted research and development in the production, isolation, purification, and application of radioactive isotopes. Initially this work supported the weapons development mission of the Laboratory. Over the years the work has evolved to support basic and applied research in many diverse fields, including nuclear medicine, biomedical studies, materials science, environmental research and the physical sciences. In the early 1970s people in the Medical Radioisotope Research Program began irradiating targets at the Los Alamos Meson Physics Facility (LAMPF) to investigate the production and recovery of medically important radioisotopes. Since then spallation production using the high intensity beam at LAMPF has become a significant source of many important radioisotopes. Los Alamos posesses other facilities with isotope production capabilities. Examples are the Omega West Reactor (OWR) and the Van de Graaf Ion Beam Facility (IBF). Historically these facilities have had limited availability for radioisotope production, but recent developments portend a significant radioisotope production mission in the future

  15. Control System Development Plan for the National Spherical Torus Experiment

    International Nuclear Information System (INIS)

    Neumeyer, C.; Mueller, D.; Gates, D.A.; Ferron, J.R.


    The National Spherical Torus Experiment (NSTX) has as one of its primary goals the demonstration of the attractiveness of the spherical torus concept as a fusion power plant. Central to this goal is the achievement of high plasma β ( = 2 micro 0 /B 2 a measure of the efficiency of a magnetic plasma confinement system). It has been demonstrated both theoretically and experimentally that the maximum achievable β is a strong function of both local and global plasma parameters. It is therefore important to optimize control of the plasma. To this end a phased development plan for digital plasma control on NSTX is presented. The relative level of sophistication of the control system software and hardware will be increased according to the demands of the experimental program in a three phase plan. During Day 0 (first plasma), a simple coil current control algorithm will initiate plasma operations. During the second phase (Day 1) of plasma operations the control system will continue to use the preprogrammed algorithm to initiate plasma breakdown but will then change over to a rudimentary plasma control scheme based on linear combinations of measured plasma fields and fluxes. The third phase of NSTX plasma control system development will utilize the rtEFIT code, first used on DIII-D, to determine, in real-time, the full plasma equilibrium by inverting the Grad-Shafranov equation. The details of the development plan, including a description of the proposed hardware will be presented

  16. Update on Ultrasonic Thermometry Development at Idaho National Laboratory

    Energy Technology Data Exchange (ETDEWEB)

    Joshua Daw; Joy Rempe; John Crepeau


    The Idaho National Laboratory (INL) has initiated an effort to evaluate the viability of using ultrasonic thermometry technology as an improved sensor for detecting temperature during irradiation testing of advanced fuels proposed within the Fuel Cycle Research and Development (FCR&D) program sponsored by the U.S. Department of Energy (US DOE). Ultrasonic thermometers (UTs) work on the principle that the speed at which sound travels through a material (acoustic velocity) is dependent on the temperature of the material. UTs have several advantages over other types of temperature sensors . UTs can be made very small, as the sensor consists only of a small diameter rod which may or may not require a sheath. Measurements may be made up to very high temperature (near the melting point of the sensor material) and, as no electrical insulation is required, shunting effects observed in traditional high temperature thermocouple applications are avoided. Most attractive, however, is the ability to introduce multiple acoustic discontinuities into the sensor, as this enables temperature profiling with a single sensor. The current paper presents initial results from FCR&D UT development efforts. These developments include improved methods for fabricating magnetostrictive transducers and joining them to waveguides, characterization of candidate sensor materials appropriate for use in FCR&D fuels irradiations (both ceramic fuels in inert gas and sodium bonded metallic fuels), enhanced signal processing techniques, and tests to determine potential accuracy and resolution.

  17. Foods That Can Affect Fertility (United States)

    ... Affect Fertility Print Email Foods That Can Affect Fertility By Caroline Kaufman, MS, RDN Published January 30, ... impact on the ability to conceive. Women and Fertility To prepare for pregnancy and enhance fertility, maintain ...

  18. The intimate genetics of Drosophila fertilization (United States)

    Loppin, Benjamin; Dubruille, Raphaëlle; Horard, Béatrice


    The union of haploid gametes at fertilization initiates the formation of the diploid zygote in sexually reproducing animals. This founding event of embryogenesis includes several fascinating cellular and nuclear processes, such as sperm–egg cellular interactions, sperm chromatin remodelling, centrosome formation or pronuclear migration. In comparison with other aspects of development, the exploration of animal fertilization at the functional level has remained so far relatively limited, even in classical model organisms. Here, we have reviewed our current knowledge of fertilization in Drosophila melanogaster, with a special emphasis on the genes involved in the complex transformation of the fertilizing sperm nucleus into a replicated set of paternal chromosomes. PMID:26246493

  19. The need to improve fertility awareness

    Directory of Open Access Journals (Sweden)

    Joyce Harper


    Full Text Available Women and men globally are delaying the birth of their first child. In the UK, the average age of first conception in women is 29 years. Women experience age-related fertility decline so it is important that men and women are well-informed about this, and other aspects of fertility. A group of UK stakeholders have established the Fertility Education Initiative to develop tools and information for children, adults, teachers, parents and healthcare professionals dedicated to improving knowledge of fertility and reproductive health.

  20. Cancer and fertility: strategies to preserve fertility. (United States)

    Diedrich, K; Fauser, B C J M; Devroey, P


    Fertility preservation is a key component of cancer management in young people. The Fourth Evian Annual Reproduction Workshop Meeting was held in April 2009 to discuss cancer and fertility in young adults. Specialists in oncology, assisted reproduction, embryology and clinical genetics presented published data and ongoing research on cancer and fertility, with particular focus on strategies to preserve fertility. This report is based on the expert presentations and group discussions, supplemented with publications from literature searches and the authors' knowledge. Fertility preservation should be considered for all young people undergoing potentially gonadotoxic cancer treatment. A variety of options are required to facilitate safe and effective fertility preservation for individual patients. Sperm banking is a simple and low-cost intervention. Embryo cryopreservation is the only established method of female fertility preservation. Oocyte cryopreservation offers a useful option for women without a male partner. Emergency ovarian stimulation and cryopreservation of ovarian tissue (followed by tissue transplantation or in-vitro maturation of oocytes) are experimental techniques for women who require urgent cancer treatment. Further prospective studies are required to validate cryopreservation of oocytes and ovarian tissue, in-vitro maturation of oocytes and new vitrification techniques and to identify any long-term sequelae of slow freezing of embryos. Copyright © 2010 Reproductive Healthcare Ltd. Published by Elsevier Ltd. All rights reserved.

  1. How to influence fertility: the experience so far. (United States)

    Weeks, J R


    Even though fertility in the US is 2, the population grows each year by 2.5 million people due to natural increase and immigration. The US has never had a formal population policy to influence its birth rate. Yet the US government advises other nations, especially developing nations, how they should go about reducing their fertility. Instead the US can learn from population policies of direct disincentives, such as no income tax allowance for 3 children. In Indonesia, the president and Islamic religious leaders strongly support family planning. In Mexico, both the public and private sectors provide family planning services. The US does not have experience in influencing fertility declines, since fertility declined due to economic development over a period of time. Some scholars claim that there are 3 preconditions for a sustained decline in fertility, all of which have significance for setting population policies. The 1st is called rational choice in which conditions are such in a society that women can make their own decision. For example, the existence of legislation that guarantees women the right to act in their own interest, including the right to make their own reproductive decisions. The 2nd involves policies or conditions that motivate individuals and/or couples to limit family size. Incentives and disincentives can provide the needed motivation. For example, the government pays a woman for not having a child for a specific interval. The last precondition includes the necessity of having means available to limit family size. These means include knowledge of contraceptive methods and accessibility to them.

  2. Digital divide and digital opportunity: Comparison, analysis and strategies for sustainable development in developing nations

    International Nuclear Information System (INIS)

    Bhunia, C.T.; Onime, C.


    The world is witnessing a new digital economic order which may be quantified by the diffusion of information technology and globalization process. The current information technology gap (digital divide) between developed countries and developing countries is huge. Improvements in information technology (measured by the digital opportunity index) usually open up an opportunity for national/regional growth and development. There is a need for scientific investigation on the digital divide, digital opportunity index and their consequences. This paper presents a critical analysis of existing digital divide and its trends, it also investigates the relationship between the digital divide and the digital opportunity index. A mathematical model based on analysis of the growing digital divide is presented as a possible tool for combating and eradicate the digital divide gap which is only possible if developing and poor nations take advantage of the digital opportunities that can transform them into global competitive partners in digital knowledge economy. (author)

  3. Toxic effects of irgarol and diuron on sea urchin Paracentrotus lividus early development, fertilization, and offspring quality. (United States)

    Manzo, S; Buono, S; Cremisini, C


    Irgarol and Diuron are the most representative "organic booster biocides" that replaced organotin compounds in antifouling paints. It cannot be assumed beforehand that their use will have no environmental impact: more ecotoxicological data and a significant environmental monitoring are required. Spermio and embryotoxicities of the biocides Irgarol and Diuron were investigated on Paracentrotus lividus, the dominant echinoid species of the Mediterranean Sea. Spermiotoxicity was studied by assessing the effects of sperm exposure on fertilization rate as well as on the induction of transmissible damages to the offspring. Embryotoxicity was studied by assessing the developmental defects in the exposed larvae. The experimental results show a Diuron EC50 of 2.39 (+/- 0.21) mg/L with a NOEL of 0.25 mg/L for embryos, and of 5.09 (+/- 0.45) mg/L with a NOEL of 0.5 mg/L for sperms, respectively. Data obtained from the embryotoxicity test on Irgarol [EC50 0.99 (+/- 0.69) mg/L] are of the same order of magnitude as the literature data about Japanese urchins. Spermiotoxicity tests show an Irgarol EC50 of 9.04 (+/- 0.45) mg/L with a NOEL of 0.1 mg/L. These data show the different sensitivities of the two tests: embryos are more sensitive than sperms for both the tested chemicals and Diuron seems to be the less toxic one. Moreover, as a major output of the experimental work, tested herbicides exert transmissible damage to spermatozoa evidenced by larval malformations in the offspring, mainly P1 type (skeletal alterations). The comparison of the endpoints results offers an interesting indication of a probable different mode of action (Irgarol seems to interact with calcium homeostasis) of the two biocides.

  4. Changes in Marriage and Fertility Behavior: Behavior versus Attitudes of Young Adults. (United States)

    Moore, Kristin A.; Stief, Thomas M.


    Analyzes attitudes and values concerning marriage and fertility using data from the 1987 wave of the National Survey of Children. Most respondents were aged 18 to 22. Their views on marriage, divorce, abortion, and related topics should be taken into account in developing policy. (DM)

  5. 77 FR 16651 - National Defense Resources Preparedness (United States)


    ... commercial sectors for research and development and for acquisition of materials, services, components, and... distribution of farm equipment and commercial fertilizer; (2) the Secretary of Energy with respect to all forms... the National Labor Relations Board, the Federal Labor Relations Authority, the National Mediation...

  6. Modeling the transition towards a sustainable energy production in developing nations

    NARCIS (Netherlands)

    Thiam, Djiby-Racine; Benders, René M.J.; Moll, Henri C.

    The paper investigates how renewable technologies could promote the transition towards a sustainable energy production in developing nations. Based on two different developing nations in terms of economic, technological and institutional structure: South Africa and Senegal, we implemented scenarios

  7. Frequency selective bolometer development at Argonne National Laboratory (United States)

    Datesman, Aaron; Pearson, John; Wang, Gensheng; Yefremenko, Volodymyr; Divan, Ralu; Downes, Thomas; Chang, Clarence; McMahon, Jeff; Meyer, Stephan; Carlstrom, John; Logan, Daniel; Perera, Thushara; Wilson, Grant; Novosad, Valentyn


    We discuss the development, at Argonne National Laboratory, of a four-pixel camera suitable for photometry of distant dusty galaxies located by Spitzer and SCUBA, and for study of other millimeter-wave sources such as ultra-luminous infrared galaxies, the Sunyaev-Zeldovich (SZ) effect in clusters, and galactic dust. Utilizing Frequency Selective Bolometers (FSBs) with superconducting Transition-Edge Sensors (TESs), each of the camera's four pixels is sensitive to four colors, with frequency bands centered approximately at 150, 220, 270, and 360 GHz. The current generation of these devices utilizes proximity effect superconducting bilayers of Mo/Au or Ti/Au for TESs, along with frequency selective circuitry on membranes of silicon nitride 1 cm across and 1 micron thick. The operational properties of these devices are determined by this circuitry, along with thermal control structures etched into the membranes. These etched structures do not perforate the membrane, so that the device is both comparatively robust mechanically and carefully tailored in terms of its thermal transport properties. In this paper, we report on development of the superconducting bilayer TES technology and characterization of the FSB stacks. This includes the use of new materials, the design and testing of thermal control structures, the introduction of desirable thermal properties using buried layers of crystalline silicon underneath the membrane, detector stability control, and optical and thermal test results. The scientific motivation, FSB design, FSB fabrication, and measurement results are discussed.

  8. Operational experience and recent developments at the National Medical Cyclotron

    International Nuclear Information System (INIS)

    Conard, E.; Pac, B.; Arnott, D.W.


    The National Medical Cyclotron is a radioisotope production facility run by ANSTO and located on the grounds of the Royal Prince Alfred Hospital in Sydney, Australia. A CYCLONE 30 (IBA) cyclotron is used in the production of short-lived PET radiopharmaceuticals required by the hospital's PET Scanner and also to produce a number of bulk radiochemicals for processing and distribution throughout Australasia. Following commissioning of the cyclotron and beam lines in October 1991, and the overcoming of a number of early open-quote teething close-quote problems especially relating to the reliability of the r.f. and solid target transport systems, a steady program of improvements has been pursued. These improvements have included development of new beam diagnostics and the design and installation of a new beam line for SPECT radioisotope production. The current operations schedule includes the production of 18 FDG, 13 NH 3 , 15 O 2 and 201 Tl, 67 Ga and 123 I. This paper will discuss the process of development of the cyclotron to ably meet the present demands on it, and the problems resolved in the pursuit of this goal

  9. Practice makes perfect: participatory innovation in soil fertility management to improve rural livelihoods in East Africa

    NARCIS (Netherlands)

    Jager, de A.


    Keywords: soil nutrient balances, soil fertility degradation, East Africa , participatory innovation, experiential learning, farmer field schools, smallholder agriculture Maintaining and improving soil fertility is crucial for Africa to attain the Millennium Development Goals. Fertile soil and

  10. Practice makes perfect: participatory innovation in soil fertility management to improve rural livelihoods in East Africa

    NARCIS (Netherlands)

    Jager, de A.


    Keywords: soil nutrient balances, soil fertility degradation, East Africa , participatory innovation, experiential learning, farmer field schools, smallholder agriculture

    Maintaining and improving soil fertility is crucial for Africa to attain the Millennium Development Goals. Fertile

  11. One Way Multimedia Broadcasting as a Tool for Education and Development in Developing Nations (United States)

    Chandrasekhar, M. G.; Venugopal, D.; Sebastian, M.; Chari, B.


    An improved quality of life through education and developmental communication is an important necessity of societal up-liftment in the new millennium, especially in the developing nations. The population explosion and the associated pressure on the scarce resources to meet the basic necessities have made it more or less impossible for most of the nations to invest reasonable resources in realizing adequate channels of formal education. Thanks to the developments in satellite communication and associated technologies, new vistas are available today to provide education and developmental communication opportunities to millions of people, spread across the globe. Satellite based Digital Audio and Multimedia Broadcasting is one such new development that is being viewed as an innovative space application in the coming decades. The potential of DAB technology to reach education, information and entertainment directly to the user through a specially designed receiver could be efficiently utilized by the developing nations to overcome their difficulties in realizing formal channels of education and information dissemination. WorldSpace plans to launch three geo-stationary satellites that would cover most of the developing economies in Africa, the Mediterranean, the Middle East, Asia, Latin America and the Caribbean. Apart from a variety of digital, high quality audio channels providing news, views, education and entertainment opportunities, the end users can also get a responsive multimedia. The multimedia is being planned as a specially packaged offering that can meet the demand of students, professionals as well as certain special groups who have certain specific data and information requirements. Apart from WorldSpace, renowned agencies/firms from different parts of the world shall provide the required content to meet these requirements. Though the Internet option is available, higher telephone charges and the difficulty in getting access have made this option less

  12. Fertility considerations in young women with hematological malignancies

    DEFF Research Database (Denmark)

    Jadoul, Pascale; Kim, S Samuel; Andersen, Claus Yding


    The need for practice guidelines for fertility preservation in young women with hematological malignancies has been increased. To develop recommendations, publications relevant to fertility preservation and hematological cancers were identified through a PubMed database search and reviewed...

  13. Determinants of fertility: a regression analysis of Kenya data. (United States)

    Emereuwaonu, E U


    This study, based on data derived from a 1970 fertility and family planning survey of 346 reproductive age women in 4 Nairobi housing developments, used multivariate techniques to analyze fertility determinants in Kenya. The mean age at marriage among survey participants was 18.95 years, which corresponds with the Kenya national mean age at marriage. However, women with a secondary education showed a mean age at marriage of 20.81 years compared with 18.14 years among women with no schooling, and the mean age at marriage was 19.65 years among urban respondents comapred with 18.81 years among rural residents. Fertility was positively correlated with age but negatively associated with age at marriage. The mean number of children of women 35-44 years (6.00) was only slightly lower than the mean number of children desired by this cohort (6.39). Wives with post-primary education had the lowest number of children (1.97); those with a primary education had more children on average (5.53) than those with no schooling (3.49). Multiple regression analysis indicated a statistically significant contribution to fertility by 4 variables: age, age at marriage, couple communication, and infant-child mortality. Discussion of family planning was a consequence of high fertility. The analysis failed to indicate a trend toward smaller family size. Even women in the youngest age group (15-24 years) expressed adherence to traditional reproductive values. 42% of respondents saw nothing wrong with having large numbers of children. 71% agreed that large family size represents a burden, especially in terms of education. This suggest that the introduction of compulsory free education and better housing facilities could serve to increase fertility. It is concluded that reduction in population growth in Kenya will require modification of existing reproductive values.


    Directory of Open Access Journals (Sweden)

    Inna NOVAK


    Full Text Available Actuality: The main purpose of strategic planning is that long-term interests of sustainable development of a market economy require the use of effective measures of state regulation of economic and social processes. Objective: The aim of the article is determined to analyze the development of strategic planning methodology and practical experience of its application in the design of national development programs. Methods: When writing the article the following research methods were used: analysis and synthesis, target-oriented and monographic. Results: In Ukraine at the level of state and local government authorities strategies of development of branches, regions, cities, etc. are being developed but given the lack of state funding a unified investment strategy of the country is not developed. After analyzing development of the strategic planning methodology and examples of its application in the design of state development programs we identified the need to develop an investment strategy of the state (sectors, regions, etc., as due to defined directions and guidelines of the activity it will increase the investment level in the country and ensure national strategy “Ukraine-2020”.

  15. Obesity: modern man's fertility nemesis. (United States)

    Cabler, Stephanie; Agarwal, Ashok; Flint, Margot; du Plessis, Stefan S


    The obesity pandemic has grown to concerning proportions in recent years, not only in the Western World, but in developing countries as well. The corresponding decrease in male fertility and fecundity may be explained in parallel to obesity, and obesity should be considered as an etiology of male fertility. Studies show that obesity contributes to infertility by reducing semen quality, changing sperm proteomes, contributing to erectile dysfunction, and inducing other physical problems related to obesity. Mechanisms for explaining the effect of obesity on male infertility include abnormal reproductive hormone levels, an increased release of adipose-derived hormones and adipokines associated with obesity, and other physical problems including sleep apnea and increased scrotal temperatures. Recently, genetic factors and markers for an obesity-related infertility have been discovered and may explain the difference between fertile obese and infertile obese men. Treatments are available for not only infertility related to obesity, but also as a treatment for the other comorbidities arising from obesity. Natural weight loss, as well as bariatric surgery are options for obese patients and have shown promising results in restoring fertility and normal hormonal profiles. Therapeutic interventions including aromatase inhibitors, exogenous testosterone replacement therapy and maintenance and regulation of adipose-derived hormones, particularly leptin, may also be able to restore fertility in obese males. Because of the relative unawareness and lack of research in this area, controlled studies should be undertaken and more focus should be given to obesity as an etiolgy of male infertility.

  16. Differentials of fertility in rural Butajira.

    African Journals Online (AJOL)

    married women are using contraception, which is low to affect the fertility level significantly. Objectives: To ... The first consists of socio- economic variables ... age at marriage). Studies in a number of countries indicate that wherever fertility is high, maternal, infant and child mortality rates are high. On average, in developing ...

  17. Development of a National Repository of Digital Forensic Intelligence

    Directory of Open Access Journals (Sweden)

    Mark Weiser


    Full Text Available Many people do all of their banking online, we and our children communicate with peers through computer systems, and there are many jobs that require near continuous interaction with computer systems. Criminals, however, are also “connected”, and our online interaction provides them a conduit into our information like never before. Our credit card numbers and other fiscal information are at risk, our children's personal information is exposed to the world, and our professional reputations are on the line.The discipline of Digital Forensics in law enforcement agencies around the nation and world has grown to match the increased risk and potential for cyber crimes. Even crimes that are not themselves computer-based, may be solved or prosecuted based on digital evidence left behind by the perpetrator. However, no widely accepted mechanism to facilitate sharing of ideas and methodologies has emerged. Different agencies re-develop approaches that have been tested in other jurisdictions. Even within a single agency, there is often significant redundant work. There is great potential efficiency gain in sharing information from digital forensic investigations.This paper describes an on-going design and development project between Oklahoma State University’s Center for Telecommunications and Network Security and the Defense Cyber Crimes Center to develop a Repository of Digital Forensic Knowledge. In its full implementation, the system has potential to provide exceptional gains in efficiency for examiners and investigators. It provides a better conduit to share relevant information between agencies and a structure through which cases can be cross-referenced to have the most impact on a current investigation.

  18. Development of a National HRD Strategy Model: Cases of India and China (United States)

    Alagaraja, Meera; Wang, Jia


    National human resource development (NHRD) literature describes the importance of developing human resources at the national level and presents several models. These models are primarily concerned with the national contexts of developing and underdeveloped countries. In contrast, the NHRD models in the non-HRD literature focus primarily on…

  19. 78 FR 27408 - Eunice Kennedy Shriver National Institute of Child Health & Human Development (NICHD); Notice of... (United States)


    ... National Institute of Child Health & Human Development (NICHD); Notice of Meeting Pursuant to section 10(d... meeting of the National Advisory Child Health and Human Development Council. The meeting will be open to... Committee: National Advisory Child Health and Human Development Council. Date: June 6, 2013. Open: June 6...

  20. 77 FR 34393 - Eunice Kennedy Shriver National Institute of Child Health & Human Development; Notice of Closed... (United States)


    ... National Institute of Child Health & Human Development; Notice of Closed Meeting Pursuant to section 10(d...: National Institute of Child Health and Human Development Initial Review Group; Biobehavioral and Behavioral... Review, Eunice Kennedy Shriver National Institute o Child Health and Human Development, NIH, 6100...

  1. 76 FR 5595 - Eunice Kennedy Shriver National Institute of Child Health & Human Development; Notice of Closed... (United States)


    ... National Institute of Child Health & Human Development; Notice of Closed Meeting Pursuant to section 10(d...: National Institute of Child Health and Human Development Initial Review Group, Biobehavioral and Behavioral... Kennedy Shriver National Institute of Child Health And Human Development, NIH, 6100 Executive Blvd., Room...

  2. 77 FR 19677 - Eunice Kennedy Shriver National Institute of Child Health & Human Development; Notice of Closed... (United States)


    ... National Institute of Child Health & Human Development; Notice of Closed Meeting Pursuant to section 10(d... of Committee: National Institute of Child Health and Human Development Special Emphasis Panel, ZHD1... of Scientific Review, Eunice Kennedy Shriver National Institute of Child Health and Human Development...

  3. 76 FR 76169 - Eunice Kennedy Shriver National Institute of Child Health & Human Development Notice of Meeting (United States)


    ... National Institute of Child Health & Human Development Notice of Meeting Pursuant to section 10(a) of the... Committee: National Institute of Child Health and Human Development Special Emphasis Panel; ZHD1 DSR-K 58... Scientific Review, National Institute of Child Health and Human Development, 6100 Executive Boulevard, [[Page...

  4. 77 FR 5036 - Eunice Kennedy Shriver National Institute of Child Health & Human Development; Notice of Closed... (United States)


    ... National Institute of Child Health & Human Development; Notice of Closed Meeting Pursuant to section 10(d...: National Institute of Child Health and Human Development Special Emphasis Panel; Safety and efficacy of... Kennedy Shriver National Institute of Child Health and Human Development, NIH 6100 Executive Blvd., Room...

  5. Fertility prognosis for infertile couples

    DEFF Research Database (Denmark)

    Bostofte, E; Bagger, P; Michael, A


    OBJECTIVE: To develop a fertility prognosis model for infertile couples. DESIGN: Prospective follow-up study. PARTICIPANTS: In the period November 30, 1977 to June 1, 1985, 321 consecutive couples were investigated for infertility at Hvidovre University Hospital. Investigation of the female...... MEASURE: The Cox regression model was used to predict the time required to conceive based on informations provided by fertility investigations. RESULTS: Three of 16 prognostic variables (the period of infertility, the female infertility factor, and the P-test) possess significant prognostic information...

  6. Balancing Conservation with National Development: A Socio-Economic Case Study of the Alternatives to the Serengeti Road. (United States)

    Hopcraft, J Grant C; Bigurube, Gerald; Lembeli, James Daudi; Borner, Markus


    Developing countries often have rich natural resources but poor infrastructure to capitalize on them, which leads to significant challenges in terms of balancing poverty alleviation with conservation. The underlying premise in development strategies is to increase the socio-economic welfare of the people while simultaneously ensuring environmental sustainability, however these objectives are often in direct conflict. National progress is dependent on developing infrastructure such as effective transportation networks, however roads can be ecologically catastrophic in terms of disrupting habitat connectivity and facilitating illegal activity. How can national development and conservation be balanced? The proposed Serengeti road epitomizes the conflict between poverty alleviation on one hand, and the conservation of a critical ecosystem on the other. We use the Serengeti as an exemplar case-study in which the relative economic and social benefits of a road can be assessed against the ecological impacts. Specifically, we compare three possible transportation routes and ask which route maximizes the socio-economic returns for the people while minimizing the ecological costs. The findings suggest that one route in particular that circumnavigates the Serengeti links the greatest number of small and medium sized entrepreneurial businesses to the largest labour force in the region. Furthermore, this route connects the most children to schools, provisions the greatest access to hospitals, and opens the most fertile crop and livestock production areas, and does not compromise the ecology and tourism revenue of the Serengeti. This route would improve Tanzania's food security and self-reliance and would facilitate future infrastructure development which would not be possible if the road were to pass through the Serengeti. This case study provides a compelling example of how a detailed spatial analysis can balance the national objectives of poverty alleviation while maintaining

  7. Vitamin E Supplementation to Sows and Effects on Fertility Rate and Subsequent Body Development of their Weanling Piglets

    Directory of Open Access Journals (Sweden)

    D. O. Umesiobi


    Full Text Available The aim of this study was to evaluate the effects of dietary supplementation of vitamin E to sows on sow fertility and serum α-tocopherol, growth and physiological state of their weanling pigs. A total of 60 Large White gilts were randomly allotted to three groups (20 gilts per group from coitus to lactation phases over a two-parity period to evaluate the effects of dietary vitamin E on fecundity rates and litter size of sows. Each of the three dietary vitamin E treatment combinations involved 0, 40 or 70 IU/kg of dl- α-tocopheryl acetate/kg of diet, and parity 1 and 2. Sow serum α-tocopherol and Selenium (Se were collected at 30 day post coitum, 99 day of gestation and 21 day lactation. Serum α-tocopherol and Se were collected from piglets at 1 day post natum and on day 21 (weaning age. Data relating to sow fecundity and litter size were also recorded. Results indicate that body weights and body weight gains of sows and their litters increased significantly (P < 0.01 by parity, increasing more from parities 1 to 2, mostly when dietary vitamin E was increased from 40 to 70 IU/kg diet. The highest number of total piglets and number of piglets born alive (12 ± 8.9 vs. 11 ± 0.1 were obtained at parity 2 when dietary vitamin E was increased to 70 IU/kg diet. There was an increase in weights of the piglets when dietary vitamin E was increased in sow’s diet. There was a dramatic increase in serum α-tocopherol and Se concentrations following 40 and 70 IU/kg of vitamin E supplementation during the 30 and 99 day gestation and 21 day lactation periods as parity increased. Se concentrations were about 3 fold higher in the 70 IU/kg vitamin E supplemented group in parity 2 compared to the other groups. In both parities, female piglets had higher serum α-tocopherol and Se concentrations at both 2 day post natum and on day 21 (weaning compared to the male piglets. Results from this study suggest that supplementing 70 IU/kg α-tocopheryl acetate in

  8. Building human rights, peace and development within the united Nations




    War and peace have perpetually alternated in history. Consequently, peace has always been seen as an endless project, even a dream, to be in brotherhood realized by everyone across the earth. Since the XVII century the elimination of war and armed conflict has been a political and humanitarian objective of all nations in the world. Both the League of Nations and the United Nations were conceived with the spirit of eliminating the risk of war through the promotion of peace, cooperation and sol...

  9. NASA Applied Sciences' DEVELOP National Program: Summer 2010 Florida Agriculture (United States)

    Cooley, Zachary C.; Billiot, Amanda; Lee, Lucas; McKee, Jake


    The main agricultural areas in South Florida are located within the fertile land surrounding Lake Okeechobee. The Atlantic Watershed monthly rainfall anomalies showed a weak but statistically significant correlation to the Oceanic Nino Index (ONI). No other watershed s anomalies showed significant correlations with ONI or the Southern Oscillation Index (SOI). During La Nina months, less sea breeze days and more disturbed days were found to occur compared to El Nino and neutral months. The increase in disturbed days can likely by attributed to the synoptic pattern during La Nina, which is known to be favorable for tropical systems to follow paths that affect South Florida. Overall, neither sea breeze rainfall patterns nor total rainfall patterns in South Florida s main agricultural areas were found to be strongly influenced by the El Nino Southern Oscillation during our study time.

  10. Estrogen-induced abnormal accumulation of fat cells in the rat penis and associated loss of fertility depends upon estrogen exposure during critical period of penile development. (United States)

    Goyal, H O; Braden, T D; Williams, C S; Dalvi, P; Mansour, M; Williams, J W


    We previously reported that diethylstilbestrol (DES) or estradiol valerate (EV) exposure at a dose of 0.10-0.12 mg/kg, or higher, per day, on alternate days, from postnatal days 2-12, resulted in abnormal penis development and infertility (H. O. Goyal et al., 2005, J. Androl. 26, 32-43). The objective of this study was to identify a critical developmental period(s) during which EV exposure results in the observed penile abnormalities. Male pups received EV at a dose of 0.10-0.12 mg/kg on postnatal day(s) 1, 1-3, 4-6, 1-6, 7-12, 13-18, 19-24, or 25-30. Fertility was tested at 102-115 days of age and tissues were examined at 117-137 days. Both penile morphology and fertility were unaltered in rats treated with EV after 12 days of age. Conversely, except in rats treated on postnatal day 1 only, none of the males treated prior to 12 days of age sired pups, and all had abnormal penises, including varying degrees of abnormal accumulation of fat cells and loss of cavernous spaces and smooth muscle cells in the corpora cavernosa penis, which were maximal in the 1-6-day group. Also, the preputial sheath was partially released or its release was delayed, and the weight of the bulbospongiosus muscle was significantly reduced. Plasma testosterone (T) in the 1-6- and 4-6-day groups and intratesticular T in the 4-6-day group were significantly lower. The testosterone surge, characteristic of controls in the first week of life, was suppressed in the 1-3-day group. Estrogen receptor alpha mRNA expression was enhanced in the body of the penis in the 1-3-day group, but not in the 13-18-day group. Hence, EV exposure prior to 12 days of age (as short as 1-3 days postnatal), but not after 12 days of age, results in long-term abnormal penile morphology, characterized by abnormal accumulation of fat cells in the corpora cavernosa penis and, consequently, loss of fertility.

  11. Influence of Insulin-Like Growth Factor-I on Maturation and Fertilization Rate of Immature Oocyte and Embryo Development in NMRI Mouse with TCM199 and α-MEM Medium. (United States)

    Toori, Mehdi Akbartabar; Mosavi, Esmaeil; Nikseresht, Mohsen; Barmak, Mehrzad Jafari; Mahmoudi, Reza


    In vitro maturation (IVM) of oocytes and subsequent, in vitro fertilization (IVF) for the generation of embryos in the laboratory has important values. Growth factors are a component of a complex system of autocrine and paracrine factors that have a regulatory role in ovarian function and affect oocyte maturation. Therefore, the aim of this study is to evaluate the effect of IGF-I on IVM and IVF of mice oocytes during culture with α-MEM and TCM199 medium. Cumulus oocyte complexes (COCs) and denuded oocyte were obtained from 4-6 week old NMRI mice and underwent in vitro maturation and in vitro fertilization in presence or absence of IGF-I with α-MEM and TCM199. Maturation rate (79.6%), fertilization rate (87.2%), two cells development rate (79.5%) and blastocyst rate(43.2%) was higher in COCs cultured in α-MEM with IGF-I, while lower maturation rate (50.6%) fertilization rate (61%), two cells development rate (48.8%) and blastocyst rate(14.6%) were seen in cultured denuded oocytes (DOs) in TCM199 without growth factor. As well as, maturation fertilization, two cells development and blastocyst rates in COCs were higher than DOs. Our findings have shown that IGF-I is involved in the oocyte biology and improve the oocyte maturation, fertilization and embryo development to blastocyst competence in vitro. In addition, it has also shown that cumulus cells are vital for oocyte development when IGF-1 added to the mediums.

  12. Obesogens and male fertility. (United States)

    Cardoso, A M; Alves, M G; Mathur, P P; Oliveira, P F; Cavaco, J E; Rato, L


    In the last decades, several studies evidenced a decrease in male fertility in developed countries. Although the aetiology of this trend in male reproductive health remains a matter of debate, environmental compounds that predispose to weight gain, namely obesogens, are appointed as contributors because of their action as endocrine disruptors. Obesogens favour adipogenesis by an imbalance of metabolic processes and can be found virtually everywhere. These compounds easily accumulate in tissues with high lipid content. Obesogens change the functioning of male reproductive axis, and, consequently, the testicular physiology and metabolism that are pivotal for spermatogenesis. The disruption of these tightly regulated metabolic pathways leads to adverse reproductive outcomes. Notably, adverse effects of obesogens may also promote disturbances in the metabolic performance of the following generations, through epigenetic modifications passed by male gametes. Thus, unveiling the molecular pathways by which obesogens induce toxicity that may end up in epigenetic modifications is imperative. Otherwise, a transgenerational susceptibility to metabolic diseases may be favoured. We present an up-to-date overview of the impact of obesogens on testicular physiology, with a particular focus on testicular metabolism. We also address the effects of obesogens on male reproductive parameters and the subsequent consequences for male fertility. © 2016 World Obesity Federation.

  13. Education stalls and subsequent stalls in African fertility: A descriptive overview

    Directory of Open Access Journals (Sweden)

    Anne Goujon


    Full Text Available Background: Recent stalls in fertility decline have been observed in a few countries in sub-Saharan Africa, and so far no plausible common reason has been identified in the literature. This paper develops the hypothesis that these fertility stalls could be associated with stalls in the progress of education among the women of the relevant cohorts, possibly resulting partly from the Structural Adjustment Programs (SAPs of the 1980s. Methods: We descriptively link the change in the education composition of successive cohorts of young women in sub-Saharan Africa and the recent fertility stalls. We use reconstructed data on population by age, gender, and level of education from www.wittgenstein, and fertility rates from the United Nations. Results: In most sub-Saharan African countries, we observe that the same countries that had fertility stalls had a stall in the progress of education, particularly for young women who were of primary school age during the 1980s, when most of the countries were under structural adjustment. Conversely, stalls in fertility are less common in countries that did not have an education stall, possibly in relation to SAPs. Conclusions: The results point to the possibility of a link between the recent fertility stalls and discontinuities in the improvement of the education of the relevant cohorts, which in turn could be related to the SAPs in the 1980s. This descriptive finding now needs to be corroborated through more detailed cohort-specific fertility analysis. If the education-fertility link can be further established, it will have important implications for the projections of population growth in affected countries.

  14. Development of a Cultural Connectedness Scale for First Nations youth. (United States)

    Snowshoe, Angela; Crooks, Claire V; Tremblay, Paul F; Craig, Wendy M; Hinson, Riley E


    Despite a growing recognition of cultural connectedness as an important protective factor for First Nations (FN) peoples' health, there remains a clear need for a conceptual model that organizes, explains, and leads to an understanding of the resiliency mechanisms underlying this concept for FN youth. The current study involved the development of the Cultural Connectedness Scale (CCS) to identify a new scale of cultural connectedness. A sample of 319 FN, Métis, and Inuit youths enrolled in Grades 8-12 from reserve and urban areas in Saskatchewan and Southwestern Ontario, Canada, participated in the current study. A combination of rational expert judgments and empirical data were used to refine the pool of items to a set that is a representative sample of the indicators of the cultural connectedness construct. Exploratory factor analysis (EFA) was used to examine the latent structure of the cultural connectedness items, and a confirmatory factor analysis was used to test the fit of a more parsimonious version of the final EFA model. The resulting 29-item inventory consisted of 3 dimensions: identity, traditions, and spirituality. Criterion validity was demonstrated with cultural connectedness dimensions correlating well with other youth well-being indicators. The conceptualization and operationalization of the cultural connectedness has a number of potential applications both for research and prevention. This study provides an orienting framework that guides measurement of cultural connectedness that researchers need to further explore the role of culture in enhancing resiliency and well-being among FN youth in Canada. 2015 APA, all rights reserved

  15. Idaho National Laboratory Directed Research and Development FY-2009

    Energy Technology Data Exchange (ETDEWEB)


    The FY 2009 Laboratory Directed Research and Development (LDRD) Annual Report is a compendium of the diverse research performed to develop and ensure the INL's technical capabilities can support the future DOE missions and national research priorities. LDRD is essential to the INL - it provides a means for the laboratory to pursue novel scientific and engineering research in areas that are deemed too basic or risky for programmatic investments. This research enhances technical capabilities at the laboratory, providing scientific and engineering staff with opportunities for skill building and partnership development. Established by Congress in 1991, LDRD proves its benefit each year through new programs, intellectual property, patents, copyrights, publications, national and international awards, and new hires from the universities and industry, which helps refresh the scientific and engineering workforce. The benefits of INL's LDRD research are many as shown in the tables below. Last year, 91 faculty members from various universities contributed to LDRD research, along with 7 post docs and 64 students. Of the total invention disclosures submitted in FY 2009, 7 are attributable to LDRD research. Sixty three refereed journal articles were accepted or published, and 93 invited presentations were attributable to LDRD research conducted in FY 2009. The LDRD Program is administered in accordance with requirements set in DOE Order 413.2B, accompanying contractor requirements, and other DOE and federal requirements invoked through the INL contract. The LDRD Program is implemented in accordance with the annual INL LDRD Program Plan, which is approved by the DOE, Nuclear Energy Program Secretarial Office. This plan outlines the method the laboratory uses to develop its research portfolio, including peer and management reviews, and the use of other INL management systems to ensure quality, financial, safety, security and environmental requirements and risks are

  16. Towards SEA for the developing nations of Asia

    International Nuclear Information System (INIS)

    Briffett, Clive; Obbard, Jeffrey Philip; Mackee, Jamie


    In the developing and transitional countries of Asia, environmental impact assessment (EIA) has been widely practiced as a planning tool that identifies the potential impacts associated with developments and determines their level of significance and the need for mitigating measures. Not withstanding its extensive use in many Asian countries, certain limitations are now being increasingly recognised with regard to achieving sustainable development within the planning process. It is also noted that the natural environment in Asia has continued to be severely degraded despite the adoption of EIA. This research project was undertaken at the National University of Singapore to review the status on the implementation of EIA procedures and to investigate the status and potential of strategic environmental assessment (SEA) in Asia. The research project generally investigated the existing physical attributes of six countries including Hong Kong and Singapore, Malaysia and the Philippines, Sri Lanka and Vietnam and discussed their prevailing environmental conditions. It more specifically reviewed policymaking and environmental planning, environmental legislation and the practice and procedures of environmental impact assessment. It also evaluated environmental assessment education and training activities. In some cases such as Hong Kong, an opportunity to analyse actual SEA practice was included. In other cases, the potential for possible take up of formal SEA was assessed. A comparative review assesses the degree to which EIA and SEA procedures have been utilized, considers how the use of SEA could overcome the deficiencies of the EIA project-based system and includes aspects of meeting sustainability criteria. Results show that the use and application of EIA is relatively strong across all countries with the possible exception of Singapore which relies more heavily on its planning and control system to address potential environmental impacts arising from development

  17. Development of a biomarkers database for the National Children's Study

    International Nuclear Information System (INIS)

    Lobdell, Danelle T.; Mendola, Pauline


    The National Children's Study (NCS) is a federally-sponsored, longitudinal study of environmental influences on the health and development of children across the United States ( Current plans are to study approximately 100,000 children and their families beginning before birth up to age 21 years. To explore potential biomarkers that could be important measurements in the NCS, we compiled the relevant scientific literature to identify both routine or standardized biological markers as well as new and emerging biological markers. Although the search criteria encouraged examination of factors that influence the breadth of child health and development, attention was primarily focused on exposure, susceptibility, and outcome biomarkers associated with four important child health outcomes: autism and neurobehavioral disorders, injury, cancer, and asthma. The Biomarkers Database was designed to allow users to: (1) search the biomarker records compiled by type of marker (susceptibility, exposure or effect), sampling media (e.g., blood, urine, etc.), and specific marker name; (2) search the citations file; and (3) read the abstract evaluations relative to our search criteria. A searchable, user-friendly database of over 2000 articles was created and is publicly available at: PubMed was the primary source of references with some additional searches of Toxline, NTIS, and other reference databases. Our initial focus was on review articles, beginning as early as 1996, supplemented with searches of the recent primary research literature from 2001 to 2003. We anticipate this database will have applicability for the NCS as well as other studies of children's environmental health

  18. National Fire Plan Research and Development 2001 Business Summary (United States)

    USDA Forest Service


    Wildland fire remains a serious concern to the people of our Nation. This concern has been turned into action in the form of the National Fire Plan (NFP), an accelerated interagency effort, begun after the disastrous 2000 fire season, to step up, coordinate, and concentrate activity on reducing fire risks.

  19. 76 FR 77544 - Eunice Kennedy Shriver National Institute of Child Health & Human Development; Notice of Meeting (United States)


    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health Eunice Kennedy Shriver National Institute of Child Health & Human Development; Notice of Meeting Pursuant to section 10(a) of the... Secretary, National Children's Study, Eunice Kennedy Shriver National Institute of Child Health and Human...

  20. 78 FR 6127 - Eunice Kennedy Shriver National Institute of Child Health & Human Development; Notice of Meeting (United States)


    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health Eunice Kennedy Shriver National Institute of Child Health & Human Development; Notice of Meeting Pursuant to section 10(a) of the...: Kate Winseck, MSW, Executive Secretary, National Children's Study, Eunice Kennedy Shriver National...

  1. The value of symbiotic nitrogen fixation by grain legumes in comparison to the cost of nitrogen fertilizer used in developing countries

    International Nuclear Information System (INIS)

    Hardarson, G.; Bunning, S.; Montanez, A.; Roy, R.; MacMillan, A.


    A great challenge lies in devising more sustainable farming systems without compromising food production levels and food security. Obviously, increasing productivity is necessary to accommodate growth in the global population. World wide, the environmental factors that most severely restrict plant growth are the availability of water and nitrogen. The challenges in developing countries are to find ways of meeting this additional nitrogen demand without concomitant degrading natural productivity. Widespread adoption of biological nitrogen fixation (BNF) would contribute to this goal. BNF, together with adequate N management in the ecosystem, appears to be the most promising alternative to increasing the use of inorganic fertiliser nitrogen. BNF technologies represent economic, sustainable and environmentally friendly means of ensuring the nitrogen requirement of an agro-ecosystem. Here we investigate the value of BNF by grain legumes and compares it to the cost of nitrogen fertilizer used in developing countries. Our data show that major grain legumes fix approximately 11.1 million metric tons of nitrogen per annum in developing countries. If this N was supplied by inorganic fertiliser one would have to apply at least double that amount to achieve the same yields, and this would cost approximately 6.7 billion US dollars. As the eight major grain legumes grown in developing countries contribute 30 - 40% of the annual N requirement the contribution of BNF is of great economic and environmental importance. (author)

  2. Commonly used fertility drugs, a diet supplement, and stress force AMPK-dependent block of stemness and development in cultured mammalian embryos. (United States)

    Bolnick, Alan; Abdulhasan, Mohammed; Kilburn, Brian; Xie, Yufen; Howard, Mindie; Andresen, Paul; Shamir, Alexandra M; Dai, Jing; Puscheck, Elizabeth E; Rappolee, Daniel A


    The purpose of the present study is to test whether metformin, aspirin, or diet supplement (DS) BioResponse-3,3'-Diindolylmethane (BR-DIM) can induce AMP-activated protein kinase (AMPK)-dependent potency loss in cultured embryos and whether metformin (Met) + Aspirin (Asa) or BR-DIM causes an AMPK-dependent decrease in embryonic development. The methods used were as follows: culture post-thaw mouse zygotes to the two-cell embryo stage and test effects after 1-h AMPK agonists' (e.g., Met, Asa, BR-DIM, control hyperosmotic stress) exposure on AMPK-dependent loss of Oct4 and/or Rex1 nuclear potency factors, confirm AMPK dependence by reversing potency loss in two-cell-stage embryos with AMPK inhibitor compound C (CC), test whether Met + Asa (i.e., co-added) or DS BR-DIM decreases development of two-cell to blastocyst stage in an AMPK-dependent (CC-sensitive) manner, and evaluate the level of Rex1 and Oct4 nuclear fluorescence in two-cell-stage embryos and rate of two-cell-stage embryo development to blastocysts. Met, Asa, BR-DIM, or hyperosmotic sorbitol stress induces rapid ~50-85 % Rex1 and/or Oct4 protein loss in two-cell embryos. This loss is ~60-90 % reversible by co-culture with AMPK inhibitor CC. Embryo development from two-cell to blastocyst stage is decreased in culture with either Met + Asa or BR-DIM, and this is either >90 or ~60 % reversible with CC, respectively. These experimental designs here showed that Met-, Asa-, BR-DIM-, or sorbitol stress-induced rapid potency loss in two-cell embryos is AMPK dependent as suggested by inhibition of Rex1 and/or Oct4 protein loss with an AMPK inhibitor. The DS BR-DIM or fertility drugs (e.g., Met + Asa) that are used to enhance maternal metabolism to support fertility can also chronically slow embryo growth and block development in an AMPK-dependent manner.

  3. The human factor in national development: some reflections on population and development in Nigeria. (United States)

    Ukaegbu, C C


    The relationship between the effective utilization of human resources and successful socioeconomic development in Nigeria is examined. The author argues that Nigeria's current socioeconomic difficulties cannot be blamed on population growth alone, and maintains that "underutilization of human resources; lopsided production and distribution mechanisms; economic depression; and under-developed science and technology system; erratic climatic and agronomic conditions; the illegal exportation of food; [and] corruption and mismanagement of revenue, all constitute forces that simultaneously limit the national capacity to produce more resources for the growing population." excerpt

  4. Aspects of a new world development strategy. I. Financial transfers from developed to developing nations

    Energy Technology Data Exchange (ETDEWEB)

    Munduch, G. (Inst. for Advanced Studies, Vienna, Austria); Weinberg, C.B.


    A global econometric model is used in this study to evaluate the effect of a grant-in-aid transfer from the developed market economies to the non-oil-exporting developing economies. Two alternative financing schemes, expenditure diversion and direct taxation, are supposed in the paying countries so that the government current amount balance is not disturbed. The results suggest that the developing countries would benefit greatly from the implementation of any transfer scheme. The developed countries, under either of the assumptions of this study, would not realize any substantial benefits from offering such a payment.

  5. 75 FR 12243 - Eunice Kennedy Shriver National Institute of Child Health & Human Development; Notice of Closed... (United States)


    ... HUMAN SERVICES National Institutes of Health Eunice Kennedy Shriver National Institute of Child Health & Human Development; Notice of Closed Meeting Pursuant to section 10(d) of the Federal Advisory Committee... National Institute of Child Health and Human Development, NIH, 6100 Executive Blvd. Room 5B01, Bethesda, MD...

  6. 76 FR 40738 - Eunice Kennedy Shriver National Institute of Child Health & Human Development; Notice of Closed... (United States)


    ... HUMAN SERVICES National Institutes of Health Eunice Kennedy Shriver National Institute of Child Health & Human Development; Notice of Closed Meeting Pursuant to section 10(d) of the Federal Advisory Committee..., Eunice Kennedy Shriver National Institute of Child Health and Human Development, NIH, 6100 Executive Blvd...

  7. 75 FR 34457 - Eunice Kennedy Shriver National Institute of Child Health & Human Development; Notice of Closed... (United States)


    ... HUMAN SERVICES National Institutes of Health Eunice Kennedy Shriver National Institute of Child Health & Human Development; Notice of Closed Meeting Pursuant to section 10(d) of the Federal Advisory Committee..., National Institute of Child Health, And Human Development, 6100 Executive Boulevard, Room 5B01, Bethesda...

  8. 75 FR 12244 - Eunice Kennedy Shriver National Institute of Child Health & Human Development; Notice of Closed... (United States)


    ... HUMAN SERVICES National Institutes of Health Eunice Kennedy Shriver National Institute of Child Health & Human Development; Notice of Closed Meeting Pursuant to section 10(d) of the Federal Advisory Committee... Scientific Review, Eunice Kennedy Shriver National Institute of Child Health and Human Development, NIH, 6100...

  9. 76 FR 40737 - Eunice Kennedy Shriver National Institute of Child Health & Human Development; Notice of Closed... (United States)


    ... HUMAN SERVICES National Institutes of Health Eunice Kennedy Shriver National Institute of Child Health & Human Development; Notice of Closed Meeting Pursuant to section 10(d) of the Federal Advisory Committee... Kennedy Shriver National Institute of Child Health and Human Development, NIH, 6100 Executive Blvd., Room...

  10. 76 FR 19999 - Eunice Kennedy Shriver National Institute of Child Health & Human Development; Notice of Closed... (United States)


    ... HUMAN SERVICES National Institutes of Health Eunice Kennedy Shriver National Institute of Child Health & Human Development; Notice of Closed Meeting Pursuant to section 10(d) of the Federal Advisory Committee... Review Officer, Division of Scientific Review, National Institute of Child Health and Human Development...

  11. 78 FR 48880 - Eunice Kennedy Shriver National Institute of Child Health & Human Development; Notice of Closed... (United States)


    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health Eunice Kennedy Shriver National Institute of Child Health & Human Development; Notice of Closed Meeting Pursuant to section 10(d... Kennedy Shriver National Institute of Child Health and Human Development, NIH, 6100 Executive Blvd., Room...

  12. 76 FR 18566 - Eunice Kennedy Shriver National Institute of Child Health & Human Development; Notice of Closed... (United States)


    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health Eunice Kennedy Shriver National Institute of Child Health & Human Development; Notice of Closed Meeting Pursuant to section 10(d... Review, Eunice Kennedy Shriver National Institute of Child Health and Human Development, NIH, 6100...

  13. 76 FR 65516 - Eunice Kennedy Shriver National Institute of Child Health & Human Development; Notice of Closed... (United States)


    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health Eunice Kennedy Shriver National Institute of Child Health & Human Development; Notice of Closed Meeting Pursuant to section 10(d... Kennedy Shriver National Institute of Child Health and Human Development, NIH, 6100 Executive Blvd., Room...

  14. 76 FR 64092 - Eunice Kennedy Shriver National Institute of Child Health & Human Development; Notice of Closed... (United States)


    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health Eunice Kennedy Shriver National Institute of Child Health & Human Development; Notice of Closed Meeting Pursuant to section 10(d... Review, Eunice Kennedy Shriver National Institute of Child Health and Human Development, NIH, 6100...

  15. 77 FR 12599 - Eunice Kennedy Shriver National Institute of Child Health & Human Development; Notice of Closed... (United States)


    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health Eunice Kennedy Shriver National Institute of Child Health & Human Development; Notice of Closed Meeting Pursuant to section 10(d..., Eunice Kennedy Shriver National Institute of Child Health and Human Development, NIH, 6100 Executive Blvd...

  16. 78 FR 23771 - Eunice Kennedy Shriver National Institute of Child Health & Human Development; Notice of Closed... (United States)


    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health Eunice Kennedy Shriver National Institute of Child Health & Human Development; Notice of Closed Meeting Pursuant to section 10(d..., Eunice Kennedy Shriver National Institute, of Child Health And Human Development, NIH, 6100 Executive...

  17. 75 FR 36661 - Eunice Kennedy Shriver National Institute of Child Health & Human Development; Notice of Closed... (United States)


    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health Eunice Kennedy Shriver National Institute of Child Health & Human Development; Notice of Closed Meeting Pursuant to section 10(d... Review, Eunice Kennedy Shriver National Institute of Child Health and Human Development, NIH, 6100...

  18. 78 FR 70311 - Eunice Kennedy Shriver National Institute of Child Health & Human Development; Notice of Closed... (United States)


    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health Eunice Kennedy Shriver National Institute of Child Health & Human Development; Notice of Closed Meeting Pursuant to section 10(d... Scientific Review, Eunice Kennedy Shriver National Institute of Child Health and Human Development, NIH, 6100...

  19. 76 FR 11800 - Eunice Kennedy Shriver National Institute of Child Health & Human Development; Notice of Closed... (United States)


    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health Eunice Kennedy Shriver National Institute of Child Health & Human Development; Notice of Closed Meeting Pursuant to section 10(d... Review, Eunice Kennedy Shriver National Institute of Child Health and Human Development, NIH, 6100...

  20. 75 FR 36662 - Eunice Kennedy Shriver National Institute of Child Health & Human Development; Notice of Closed... (United States)


    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health Eunice Kennedy Shriver National Institute of Child Health & Human Development; Notice of Closed Meeting Pursuant to section 10(d... Kennedy Shriver National Institute of Child Health and Human Development, NIH, 6100 Executive Blvd., Room...

  1. 77 FR 1705 - Eunice Kennedy Shriver National Institute of Child Health & Human Development (NICHD); Notice of... (United States)


    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health Eunice Kennedy Shriver National Institute of Child Health & Human Development (NICHD); Notice of Meeting Pursuant to section 10(d... Kennedy Shriver National Institute of Child Health, and Human Development, NIH, 9000 Rockville Pike MSC...

  2. 76 FR 13649 - Eunice Kennedy Shriver National Institute of Child Health & Human Development; Notice of Closed... (United States)


    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health Eunice Kennedy Shriver National Institute of Child Health & Human Development; Notice of Closed Meeting Pursuant to section 10(d... of Scientific Review, Eunice Kennedy Shriver National Institute of Child Health and Human Development...

  3. 76 FR 13651 - Eunice Kennedy Shriver National Institute of Child Health & Human Development; Notice of Closed... (United States)


    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health Eunice Kennedy Shriver National Institute of Child Health & Human Development; Notice of Closed Meeting Pursuant to section 10(d... Review, OD, Eunice Kennedy Shriver National Institute of Child Health and Human Development, NIH, 6100...

  4. 78 FR 21382 - Eunice Kennedy Shriver National Institute of Child Health & Human Development; Notice of Closed... (United States)


    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health Eunice Kennedy Shriver National Institute of Child Health & Human Development; Notice of Closed Meeting Pursuant to section 10(d... Scientific Review, Eunice Kennedy Shriver National Institute of Child Health And Human Development, NIH, 6100...

  5. 77 FR 12604 - Eunice Kennedy Shriver National Institute of Child Health & Human Development; Notice of Closed... (United States)


    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health Eunice Kennedy Shriver National Institute of Child Health & Human Development; Notice of Closed Meetings Pursuant to section 10(d... Kennedy Shriver National Institute of Child Health and Human Development, NIH, 6100 Executive Blvd., Room...

  6. 77 FR 58855 - Eunice Kennedy Shriver National Institute of Child Health & Human Development; Notice of Closed... (United States)


    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health Eunice Kennedy Shriver National Institute of Child Health & Human Development; Notice of Closed Meeting Pursuant to section 10(d... Kennedy Shriver National Institute of Child Health And Human Development, NIH, 6100 Executive Blvd., Room...

  7. 78 FR 17419 - Eunice Kennedy Shriver National Institute of Child Health & Human Development; Notice of Closed... (United States)


    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health Eunice Kennedy Shriver National Institute of Child Health & Human Development; Notice of Closed Meeting Pursuant to section 10(d... Kennedy Shriver National Institute of Child Health and Human Development, NIH, 6100 Executive Blvd., Room...

  8. 77 FR 12601 - Eunice Kennedy Shriver National Institute of Child Health & Human Development; Notice of Closed... (United States)


    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health Eunice Kennedy Shriver National Institute of Child Health & Human Development; Notice of Closed Meeting Pursuant to section 10(d... Kennedy Shriver National Institute, of Child Health and Human Development, NIH, 6100 Executive Blvd., Room...

  9. 76 FR 72957 - Eunice Kennedy Shriver National Institute of Child Health & Human Development; Notice of Closed... (United States)


    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health Eunice Kennedy Shriver National Institute of Child Health & Human Development; Notice of Closed Meeting Pursuant to section 10(d... Kennedy Shriver National Institute of Child Health And Human Development, NIH, 6100 Executive Blvd., Room...

  10. 77 FR 37424 - Eunice Kennedy Shriver National Institute of Child Health & Human Development; Notice of Meeting (United States)


    ... National Institute of Child Health & Human Development; Notice of Meeting Pursuant to section 10(a) of the... Children's Study, Eunice Kennedy Shriver National Institute of Child Health and Human Development, NIH... National Children's Study Advisory Committee. The meeting will be open to the public, with attendance...

  11. 75 FR 7485 - Eunice Kennedy Shriver National Institute of Child Health & Human Development; Amended Notice of... (United States)


    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health Eunice Kennedy Shriver National Institute of Child Health & Human Development; Amended Notice of Meeting Notice is hereby given of a change in the meeting of the National Institute of Child Health and Human Development Special...

  12. 75 FR 36100 - Eunice Kennedy Shriver National Institute of Child Health & Human Development; Notice of Closed... (United States)


    ... National Institute of Child Health & Human Development; Notice of Closed Meeting Pursuant to section 10(d... Institute of Child Health and Human Development Special Emphasis Panel National Childrens Study. Date: July..., Scientific Review Administrator, Division of Scientific Review, National Institute of Child Health and Human...

  13. 76 FR 53686 - Eunice Kennedy Shriver National Institute of Child Health & Human Development; Notice of Meeting (United States)


    ... National Institute of Child Health & Human Development; Notice of Meeting Pursuant to section 10(d) of the... National Advisory Child Health and Human Development Council. The meeting will be closed to the public in... unwarranted invasion of personal privacy. Name of Committee: National Advisory Child Health and Human...

  14. 78 FR 18998 - Eunice Kennedy Shriver National Institute of Child Health & Human Development; Notice of Meeting (United States)


    ... National Institute of Child Health & Human Development; Notice of Meeting Pursuant to section 10(d) of the... Committee: National Institute of Child Health and Human Development Special Emphasis Panel, Diet, Obesity.... Kandasamy, Ph.D., Scientific Review Officer, Division of Scientific Review, National Institute of Child...

  15. 76 FR 35226 - Eunice Kennedy Shriver National Institute of Child Health & Human Development; Notice of Meeting (United States)


    ... National Institute of Child Health & Human Development; Notice of Meeting Pursuant to section 10(a) of the... Children's Study, Eunice Kennedy Shriver National Institute of Child Health and Human Development, NIH... National Children's Study Advisory Committee. The meeting will be open to the public, with attendance...

  16. 77 FR 5035 - Eunice Kennedy Shriver National Institute of Child Health & Human Development; Notice of Closed... (United States)


    ... National Institute of Child Health & Human Development; Notice of Closed Meeting Pursuant to section 10(d... Kennedy Shriver National Institute of Child Health and Human Development, NIH, 6100 Executive Blvd., Room... constitute a clearly unwarranted invasion of personal privacy. Name of Committee: National Institute of Child...

  17. 77 FR 16845 - Eunice Kennedy Shriver National Institute of Child Health & Human Development; Notice of Meeting (United States)


    ... National Institute of Child Health & Human Development; Notice of Meeting Pursuant to section 10(a) of the... Study, Eunice Kennedy Shriver National Institute of Child Health and Human Development, NIH, 6100... National Children's Study Advisory Committee. The meeting will be open to the public, with attendance...

  18. The mass media and national development: the case of 'baby factory ...

    African Journals Online (AJOL)

    The mass media play vital role in the national development of any nation, they provide information, education, entertainment, integration and social interaction in a country by giving insight into the happenings in the society and helping with the development of a nation. The media are also seen as an agent of change ...

  19. [Fertility preservation in oncology]. (United States)

    Chaput, Laure; Grémeau, Anne-Sophie; Vorilhon, Solène; Pons, Hanae; Chabrot, Cécile; Grèze, Victoria; Pouly, Jean-Luc; Brugnon, Florence


    Since the improvement of cancer diagnosis and treatment, survival rates of these patients increase. Gonadal damages are frequent consequences of cancer treatments with different evidence of impaired fertility. In this context, fertility preservation should be proposed to patients exposed to potentially gonadotoxic treatments. Different preservation approaches may be proposed depending on patient age, sex, cancer type and type of treatment. The indications of fertility preservation depend on sexual maturity. In young girls, ovarian cortex cryopreservation is the only technique feasible in order to preserve their reproductive potential. Vitrification of oocytes which needs ovarian stimulation or oocytes in vitro maturation is becoming more commonly performed for pubertal women to preserve their fertility. Ovarian cortex freezing could be offered to emergency fertility preservation of adult female cancer patients. In prepubertal boys, testicular tissue cryopreservation is the only line treatment for fertility preservation. For future use, various approaches are being evaluated such as spermatogonial stem cell injection or in vitro maturation. Cryopreservation of spermatozoa is, today, an established and successful technique for male adults. When there are no spermatozoa in ejaculate, sperm can be retrieved after treatment of testicular biopsy. The French bioethics law clearly indicates that fertility preservation should be proposed to patients exposed to potentially gonadotoxic treatment. Today, many approaches are possible. Fertility preservation indications are based on multidisciplinary consultations within platforms for the fertility preservation in order to optimize the patient care. Copyright © 2017 Société Française du Cancer. Published by Elsevier Masson SAS. All rights reserved.

  20. Demographic and fertility characteristics of 4 squatter settlements. (United States)

    Yusof, K; Zulkifli, S N


    The demographic and fertility profiles of 4 squatter areas, 2 with Sang Kancil, a community development project designed specifically for squatter settlements in Kuala Lumpur, are described. Data were taken from a census conducted in 1982. Figure 1 maps out the location of the study areas in the Federal Territory. The squatter household (5.4 members) varied little from the average Malaysian household. The average age of the male head of household was 40 years, i.e., not within the high fertility group; the mean duration of stay was 10 years. Household income/month averaged M$760, falling between estimates for urban and rural mean. Comparing the data on the 2 squatter areas, the non-Sang Kancil head of household was, on average, slightly older and had stayed about 2 years longer than his Sang Kancil counterpart. These differences were statistically significant. Both areas were comparable with regard to household income and size. Ethnically, the Sang Kancil areas were predominantly Malay, comprising 86% of total households. The control areas had a more mixed ethnic structure. From 1978-81, annual increases in total population had been fairly uniform, at around 2%, in non-Sang Kancil Areas. Yet, the Sang Kancil population experienced a growth spurt in 1980, which subsequently declined and appeared to level off. 1982 figures were disregarded in this analysis as they were based on a 1/2 year enumeration only. The age distribution pattern of all squatter areas combined was fairly similar to the national distribution pyramid but for a higher proportion of people in the 15-44 age group than national figures. The proportion of dependents, 0-14 years, was comparable despite having more people in this fertile age group. The proportion of infants (0-11 months) in the control population was constant, but there was a decline down to control values by the end of the surveyed period in the Sang Kancil group. In the toddler group, decreases were evident for both populations

  1. Determinants of the adoption of integrated soil fertility management ...

    African Journals Online (AJOL)

    ... yet people are still reliant on food imports, with the region registering high poverty levels. Depletion of soil fertility and the resulting decline in agricultural productivity in Mbale division has led to many attempts to develop and popularize Integrated Soil Fertility Management (ISFM) technologies that could restore soil fertility.

  2. Parental Factors Influencing the Development of Early Childhood Caries in Developing Nations: A Systematic Review. (United States)

    Rai, Nayanjot Kaur; Tiwari, Tamanna


    Early childhood caries (ECC) is one of the most prevalent and chronic conditions of childhood. Various factors including biological and dietary factors along with an overlay of parental social factors have been found to be associated with the progression of ECC. The objective of this systematic review is to synthesize available literature and to identify parent-level proximal and distal risk factors associated with the development of ECC in developing nations. Studies conducted in developing nations, published between 2005 and 2017 in English, that included children younger than 6 years and examined ECC were included. The outcome of interest were parental risk factors, which included parental knowledge, behavior, attitudes, sense of coherence (SOC), stress, socioeconomic status (SES), education, and breastfeeding duration. The studies were retrieved from MEDLINE, Ovid Medline, and PubMed. The search yielded 325 studies, of which 18 were considered eligible for inclusion in this review. Ten studies found maternal education, and seven studies found parental education to be significantly associated with ECC. SES was significantly associated with ECC in 13 studies in the form of annual household income and occupation level. Four studies observed the significant association between oral health knowledge and attitudes with ECC, whereas only two studies found maternal attitude to be associated with ECC. Breastfeeding duration was a significant risk factor in four studies. One study each found significant associations of SOC, parental distress, and secondary smoke with ECC. To date, most of the researches done in developing countries have reported distal parental factors such as income and education being significant risk factors in caries development compared to proximal risk factors in low-income groups. Only a few studies analyzed the psychosocial and behavioral factors. Interventions could be designed to improve parental oral health knowledge and behaviors in these

  3. Obesity and fertility. (United States)

    Best, Damian; Bhattacharya, Siladitya


    The prevalence of overweight and obesity in women of reproductive age has increased over the past 30 years. Infertility affects 1 in 7 couples, and female obesity is associated with anovulation. The mechanisms by which excessive fat delays time to pregnancy (TTP) appear rooted in ovulatory problems and direct effects on oocytes, causing poorer embryo development, as well as in effects on the endometrium. Weight loss in women has been shown to improve conception, but not necessarily live birth rates following fertility treatment, and further research in this area is needed. The obesity epidemic has been accompanied by a potential rise in male infertility, which has been attributed to hormonal disturbances and compromised semen parameters.

  4. Different periods of intrauterine exposure to electromagnetic field: Influence on female rats' fertility, prenatal and postnatal development

    Directory of Open Access Journals (Sweden)

    Ali S.H. Alchalabi


    Conclusion: Results suggest that long-term exposure to EMF during the pregnancy lead to chronic stress, which has detrimental effects on pre-& postnatal development and for that more studies to clarify such harmful effects are recommended.

  5. 77 FR 27468 - Eunice Kennedy Shriver National Institute of Child Health & Human Development Notice of Closed... (United States)


    ... National Institute of Child Health & Human Development Notice of Closed Meeting Pursuant to section 10(d... Institute of Child Health and Human Development Special Emphasis Panel; Topics in Development, Signaling... Review, OD, Eunice Kennedy Shriver National Institute of Child Health and Human Development, NIH, 6100...

  6. The Effect of Elevated CO2 and Increased Temperature on in Vitro Fertilization Success and Initial Embryonic Development of Single Male:Female Crosses of Broad-Cast Spawning Corals at Mid- and High-Latitude Locations

    Directory of Open Access Journals (Sweden)

    Miriam Schutter


    Full Text Available The impact of global climate change on coral reefs is expected to be most profound at the sea surface, where fertilization and embryonic development of broadcast-spawning corals takes place. We examined the effect of increased temperature and elevated CO2 levels on the in vitro fertilization success and initial embryonic development of broadcast-spawning corals using a single male:female cross of three different species from mid- and high-latitude locations: Lyudao, Taiwan (22° N and Kochi, Japan (32° N. Eggs were fertilized under ambient conditions (27 °C and 500 μatm CO2 and under conditions predicted for 2100 (IPCC worst case scenario, 31 °C and 1000 μatm CO2. Fertilization success, abnormal development and early developmental success were determined for each sample. Increased temperature had a more profound influence than elevated CO2. In most cases, near-future warming caused a significant drop in early developmental success as a result of decreased fertilization success and/or increased abnormal development. The embryonic development of the male:female cross of A. hyacinthus from the high-latitude location was more sensitive to the increased temperature (+4 °C than the male:female cross of A. hyacinthus from the mid-latitude location. The response to the elevated CO2 level was small and highly variable, ranging from positive to negative responses. These results suggest that global warming is a more significant and universal stressor than ocean acidification on the early embryonic development of corals from mid- and high-latitude locations.

  7. The demography of words: The global decline in non-numeric fertility preferences, 1993-2011. (United States)

    Frye, Margaret; Bachan, Lauren


    This paper examines the decline in non-numeric responses to questions about fertility preferences among women in the developing world. These types of response-such as 'don't know' or 'it's up to God'-have often been interpreted through the lens of fertility transition theory as an indication that reproduction has not yet entered women's 'calculus of conscious choice'. However, this has yet to be investigated cross-nationally and over time. Using 19 years of data from 32 countries, we find that non-numeric fertility preferences decline most substantially in the early stages of a country's fertility transition. Using country-specific and multilevel models, we explore the individual- and contextual-level characteristics associated with women's likelihood of providing a non-numeric response to questions about their fertility preferences. Non-numeric fertility preferences are influenced by a host of social factors, with educational attainment and knowledge of contraception being the most robust and consistent predictors.

  8. Curriculum development for a national cardiotocography education program

    DEFF Research Database (Denmark)

    Thellesen, Line; Hedegaard, Morten; Bergholt, Thomas


    OBJECTIVE: To define learning objectives for a national cardiotocography (CTG) education program based on expert consensus. DESIGN: A three-round Delphi survey. POPULATION AND SETTING: One midwife and one obstetrician from each maternity unit in Denmark were appointed based on CTG teaching...... experience and clinical obstetric experience. METHODS: Founded on national and international guidelines the research group determined six topics as important when using CTG: fetal physiology, equipment, indication, interpretation, clinical management, and communication/responsibility. In the first Delphi......, representing 18 maternity units. The final prioritized list included 40 objectives. The highest ranked objectives emphasized CTG interpretation and clinical management. The lowest ranked objectives emphasized fetal physiology. Mean ratings of relevance ranged from 3.15 to 5.00. CONCLUSIONS: National consensus...

  9. Efeito da icterícia obstrutiva na fertilidade, morfologia ovariana e desenvolvimento fetal em ratas Effect of jaundice on fertility, ovarian morphology and fetal development in rats

    Directory of Open Access Journals (Sweden)

    Vivian Resende


    Full Text Available Avaliou-se o efeito da icterícia obstrutiva na capacidade reprodutiva, morfologia ovariana e desenvolvimento fetal em ratas, utilizando 53 ratas sexualmente maduras, distribuídas em dois grupos: grupo 1 (n = 28 - ligadura do ducto biliopancreático e grupo 2 (n = 25 - controle. Pode-se concluir que, em presença de hiperbilirrubinemia, a fertilização é viável, a capacidade reprodutiva é muito reduzida, os ciclos estrais tornam-se irregulares, o epitélio vaginal permanece cornificado, os corpos lúteos ovarianos regridem, os corpos lúteos gravídicos não são alterados, aumentando progressivamente durante a prenhez, e o desenvolvimento fetal é gravemente alterado.The effect of jaundice on the reproductive capacity, ovarian morphology and fetal development in rats was assessed in 53 sexually mature rats divided into two groups: group 1 (n = 28 - submitted to ligature of the biliopancreatic duct and group 2 (n = 25 - control - submitted only to sham operation. In jaundice rats fertilization is viable, the reproductive capacity is intensive reduced, the estrus cycles becomes irregular, the corpi lutea is presented in regression, the gravidic lutea is not modified increasing gradually during the pregnancy and the fetal development is seriously impaired.

  10. Issues of biomedically assisted fertilization before the European Court of Human Rights

    Directory of Open Access Journals (Sweden)

    Bordaš Bernadet


    Full Text Available The development of biomedicine has led to the birth of the first test-tube baby in 1978, and that event gave enormous impetus for further development of biomedically assisted fertilization, but also for the development of supporting legislation. Biomedically assisted fertilization and its application raises sensitive social and moral issues, so states retain their sovereign rights in this area and enact rules and regulations that reflect their national legislative policy. Comparative studies across Europe show that national legal acts are in force in many countries, but differences exist and states persist on them. Legal regulation of biomedically assisted fertilization provides legal security for individuals who are subjected to it, making easier the legal protection in cases where individual rights are violated. This paper presents two recent judgments of the European Court of Human Rights, the subject matter of which are issues of biomedically assisted fertilization, where legal remedy is sought under Article 8 of the European Convention for the Protection of Human Rights and Fundamental Freedoms. Both judgments are in favor of the states against which complaints are filed by individuals: the Court ruled that national regulations have not violated the right to respect for the individual's private life.

  11. Training Program Organic Fertilizer Production by Microorganisms Efficient

    Directory of Open Access Journals (Sweden)

    Diana Carolina Cuevas Ordoñez


    Full Text Available This research aims to develop a training program for Organic Fertilizer Production by Efficient Microorganisms aimed at teachers of the Bolivarian National School "Jose Vicente Unda" Barinitas Parish, Municipality Bolivar, Barinas State, 2015-2016 school year. The nature of research is framed in qualitative methodology, in the form of participatory action research, with a field design under the following phases: diagnosis, planning, implementation and evaluation, supported by a depth interview, using a log audiovisual face to face and through generating scripts questions, you will have three key informants. As for the technical analysis of the information box categories in order to make comparisons and draw contrasts possible. Among the final considerations it is estimated that the creation of practical activities for the production of organic fertilizer through efficient microorganisms represents an important contribution to strengthening the socio spaces in the institution, maintaining biodiversity and reducing the negative impact to the environment.

  12. Diverging patterns of fertility decline in Uruguay

    Directory of Open Access Journals (Sweden)

    Mathías Nathan


    Full Text Available Background: The total fertility rate (TFR in Uruguay fell from 2.5 to 1.9 children per woman between 1996 and 2011. However, no study to date has examined the decline of the TFR by observing changes in fertility patterns by birth order. Objective: The main aim of this study is to analyze recent changes in fertility level and timing of childbearing by birth order in Uruguay. Methods: We estimate unconditional and conditional age- and birth-order-specific fertility rates for 1996-2011 using data from vital statistics, population census, and national population estimates. Additionally, three period summary measures of birth-order-specific fertility quantum are calculated: TFR, PATFR and TFRp*. Timing changes by birth order are examined with MAB and TMAB, focusing on MAB1 and its standard deviation and comparing their evolutions in Uruguay with those of selected countries. Results: Fertility decline fits a parity-specific stopping model with a moderate increase in the mean ages of first, second, and third births. The distribution of conditional fertility rates for first and second births depicts an asymmetric bimodal shape linked to the increasing heterogeneity of the timing of childbearing. Compared to countries with similar fertility trends, heterogeneity in the age at first birth in Uruguay is remarkably high. Conclusions: Previous studies suggest that heterogeneity in first and second birth timing is related to structural social inequalities, as women from lower social strata have not significantly changed the age at which they bear a first child, whereas women of middle to high social strata have started to postpone it. The new evidence reinforces the idea that postponement transition in Uruguay cannot be studied without considering this consolidation of social status polarization in fertility timing.

  13. Fertilizer micro-dosing

    International Development Research Centre (IDRC) Digital Library (Canada)

    is currently being replaced by a multi- stakeholder system involving NGOs, agro- dealers, microfinance institutions and farmer organizations. Under this system, farmers are linked to both credit institutions and fertilizer suppliers, with their crop production serving as collateral for fertilizer purchases. Known in. West Africa as.

  14. Restoration of soil fertility and improvement of cropping systems for sustainable development in the humid savannahs of the Ivory Coast

    International Nuclear Information System (INIS)

    Bachmann, T.


    In late 1998, FAO launched a Technical Co-operation Project to assist the government of the Ivory Coast in rural development by promoting agricultural production as the main source of economic growth, and by improving the management of natural resources. The sustainable development of the humid-savannah region and western highlands is being allotted primary consideration. The goal of the project is to replace traditional shifting cultivation with more-sustainable production systems. This paper describes the origins and scope of the problem and the research strategies being considered and employed. The project will be executed in three phases: constraint analysis and formulation of a pilot project, execution of the pilot project (1999-2003), and long-term extension (15 years) from 2004, based on the data generated in the pilot phase. (author)

  15. Global fertility and population trends. (United States)

    Bongaarts, John


    Over the past several decades, the world and most countries have undergone unprecedented demographic change. The most obvious example of this change is the rise in human numbers, and there are also important trends in fertility, family structure, mortality, migration, urbanization, and population aging. This paper summarizes past trends and projections in fertility and population. After reaching 2.5 billion in 1950, the world population grew rapidly to 7.2 billion in 2013 and the projections expect this total to be 10.9 billion by 2100. World regions differ widely in their demographic trends, with rapid population growth and high fertility continuing in the poorest countries, particularly in sub-Saharan Africa, while population decline, population aging, and very low fertility are now a key concern in many developed countries. These trends have important implications for human welfare and are of interest to policy makers. The conclusion comments briefly on policy options to address these adverse trends. Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.

  16. Fertilizer effects on attaining vegetation requirements. (United States)


    This project was developed to evaluate the effects of varying the substrate and fertilization regimes on the success of complex warm-season grass and forb seedings on recent roadside construction sites. Re-vegetating construction projects is required...

  17. Effects of 17β-estradiol, and its metabolite, 4-hydroxyestradiol on fertilization, embryo development and oxidative DNA damage in sand dollar (Dendraster excentricus) sperm


    Rempel, Mary Ann; Hester, Brian; DeHaro, Hector; Hong, Haizheng; Wang, Yinsheng; Schlenk, Daniel


    Oxidative compounds have been demonstrated to decrease the fertilization capability and viability of offspring of treated spermatozoa. As estrogen and its hydroxylated metabolites readily undergo redox cycling, this study was undertaken to determine if estrogens and other oxidants could damage DNA and impair sperm function. Sperm was preexposed to either 17β-estradiol (E2), 4-hydroxyestradiol (4OHE2) or the oxidant t-butyl hydroperoxide (t-BOOH), and allowed to fertilize untreated eggs. The f...

  18. Information technology developments within the national biological information infrastructure (United States)

    Cotter, G.; Frame, M.T.


    Looking out an office window or exploring a community park, one can easily see the tremendous challenges that biological information presents the computer science community. Biological information varies in format and content depending whether or not it is information pertaining to a particular species (i.e. Brown Tree Snake), or a specific ecosystem, which often includes multiple species, land use characteristics, and geospatially referenced information. The complexity and uniqueness of each individual species or ecosystem do not easily lend themselves to today's computer science tools and applications. To address the challenges that the biological enterprise presents the National Biological Information Infrastructure (NBII) ( was established in 1993. The NBII is designed to address these issues on a National scale within the United States, and through international partnerships abroad. This paper discusses current computer science efforts within the National Biological Information Infrastructure Program and future computer science research endeavors that are needed to address the ever-growing issues related to our Nation's biological concerns.

  19. Waste management study: Process development at Lawrence Livermore National Laboratory

    International Nuclear Information System (INIS)


    This report presents the results of an evaluation of the present Toxic Waste Control Operations at the Lawrence Livermore National Laboratory, evaluates the technologies most applicable to the treatment of toxic and hazardous wastes and presents conceptual designs of processes for the installation of a new decontamination and waste treatment facility (DWTF) for future treatment of these wastes

  20. The development of a National set of Physiology learning objectives ...

    African Journals Online (AJOL)

    Medical education in Nigeria is yearning for innovations and evidence-based changes. Physiology remains core part of basic sciences and currently there are no clear exit expectations for Nigerian Medical schools. Further to the success of a national set of Physiology learning objectives in America driven by American ...