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Sample records for nasale anwendung von

  1. KRISENZUSTÄNDE UND ANWENDUNG VON ZWANGSMASSNAHMEN IN DER PSYCHIATRIE

    Directory of Open Access Journals (Sweden)

    Vesna Šendula Jengić

    2017-01-01

    Full Text Available In der Arbeit wird über die Phänomene der Aggressivität und Gewalt bei Menschen diskutiert, wobei man besonderen Wert auf die Personen mit seelischen Störungen legt. Krisenzustände und Gewaltverhalten gibt es nicht nur in der Psychiatrie. Es kann immer zu einem solchem Zustand und Verhalten kommen und jeder kann unter bestimmten Umständen sowohl Opfer als auch Täter sein. Multikausalität und Komplexität sowie auch individuelle Umstände und situationsbezogene Faktoren, welche zum Gewaltverhalten führen können, haben nur geringen Prognosekraft. Statistische Indikatoren andererseits können falsch positive und falsch negative Ergebnisse verbergen, wobei ein Fehler in der Einschätzung das Risiko zum Erscheinen eines Verhaltens drastisch erhöhen oder zum unrechtfertigten Entziehung der Freiheit führen kann. Zwangsmaβnahmen in der Psychiatrie sind nur ausnahmsweise anzuwenden, und zwar, wenn ein gefährliches Verhalten direkt das Leben und die Gesundheit einer Person oder einer Umgebung gefährdet. Darüber hinaus ist die Dauer von Zwangsmaβnahmen auch beschränkt. Die Gesetzesregulative, insbesondere das Gesetz über den Schutz von Personen mit seelischen Störungen (Amtsblatt der Republik Kroatien Nr. 76/2014 und die Ordnung über die Arten und die Weise der Anwendung von Zwangsmaβnahmen gegenüber den Personen mit schwierigen seelischen Störungen (Amtsblatt der Republik Kroatien Nr. 16/2015, dient als zusätzlicher Schutz der Rechte dieser Patientengruppe und schreibt die Arten und die Weise der Anwendung von Zwangsmaβnahmen sowie auch die Vorgehensweise. Zusätzliche Richtlinien und Vorgehensstrategien wurden auch von den Gesellschaften für Psychiatrie gegeben. In der Arbeit wird betont, dass bessere Bedingungen, Infrastruktur und Arbeitskräfte sowie auch ständige Entwicklung und Bewertung der Arbeitsqualität in der Psychiatrie erforderlich sind. Abschlieβend werden Standards und ethische Fragen in Betracht gezogen, wie

  2. Evaluation von Bildungssoftware im Spannungsfeld von Objektivität und praktischer Anwendung

    Directory of Open Access Journals (Sweden)

    Cornelia Biffi

    2002-05-01

    Full Text Available Das Angebot an Bildungs- bzw. Lernsoftware umfasst eine breite Palette von sehr unterschiedlichen Produkten. Eigentliche Unterrichtssoftware, die speziell für den Unterricht hergestellt und auf Lehrmittel und Curriculum abgestimmt ist, gibt es kaum. Im Projekt «Lernsoftware Evaluation» des Pestalozzianums Zürich ermitteln Lehrpersonen die Qualität von Bildungssoftware, indem sie diese im Unterricht einsetzen und anhand eines Kriterienrasters beurteilen. Eine Analyse der in der Evaluation generierten Daten belegt die Problematik des Anspruchs einer objektiven Qualitätsbeurteilung. Es werden die Probleme bei der Anwendung von Kriterienraster und Beurteilungsmodus aufgezeigt und ermittelt, worin die subjektiven Qualitätsmassstäbe der Evaluierenden begründet sind. Diese Ausführungen sind Teil eines Forschungsprojekts für die Weiterentwicklung einer theoretisch fundierten, aber dennoch praxisnahen Evaluation von Bildungssoftware.

  3. Entwicklung und Anwendung von Methoden zur Bestimmung von Selen-Spezies in human-biologischem Material

    OpenAIRE

    Jäger, Thomas

    2014-01-01

    Selen ist essentieller Bestandteil von mehr als 25 physiologisch wichtigen menschlichen Enzymen. Der tägliche Bedarf wird überwiegend in Form von organischen Selenverbindungen wie Selenmethionin oder Selenocystein aus der Nahrung aufgenommen. Weitere Expositionswege sind die Einnahme von Nahrungsergänzungsmitteln zur Selensupplementation sowie die inhalative oder dermale Aufnahme von in erster Linie anorganischen Selenverbindungen oder elementarem Selen an Arbeitsplätzen der Selen-verarbeiten...

  4. Mesostrukturierung und chemische Modifikation von Kathodenmaterialien zur Anwendung in Lithium-Schwefel Batterien

    OpenAIRE

    Schneider, Artur

    2016-01-01

    Die vorliegende Dissertation beschäftigt sich mit der Strukturierung und Charakterisierung von Kohlenstoffmaterialien, ihrer chemischen Modifikation, sowie deren Einsatz als Kathodenmaterialien in Lithium-Schwefel Batterien.

  5. Eine praktische Anwendung von CMC-Flächen in der Bionik

    OpenAIRE

    Apeltauer, Christian

    2011-01-01

    Die vorliegende Arbeit beschäftigt sich mit den theoretischen Grundlagen für die Entwicklung von Oberflächen, die unter Wasser möglichst lange eine Luftschicht an sich halten können. Ein natürliches Vorbild für solche Oberflächen ist die Pflanze Salvinia molesta; technisch interessieren solche Oberflächen zur Verringerung des Wasserwiderstandes von Schiffen und als Schutz vor Besiedlung durch Wasserorganismen. Wichtigste Gleichung bei der Entwicklung solcher Oberflächen ist...

  6. Automatische Ableitung und Anwendung von Regeln für die Rekonstruktion von Fassaden aus heterogenen Sensordaten

    OpenAIRE

    Becker, Susanne

    2011-01-01

    3D-Stadtmodelle finden seit einigen Jahren in immer stärkerem Maß und in den verschiedensten Bereichen Verwendung. Sie bilden unter anderem die Grundlage bei Stadtplanungen, für virtuelle Stadtrundgänge oder für die Berechnung von Simulationen. Internetdiensten wie Google Earth oder Microsoft Bing Maps ist es zu verdanken, dass 3D-Darstellungen von Gebäuden mittlerweile auch für eine breite Öffentlichkeit allgegenwärtig sind. Die erhöhte Nachfrage nach 3D-Gebäudemodellen verlangt nach effizie...

  7. Anwendung von kathodischen Korrosionsschutzmaßnahmen bei 30 Spannbetonbrücken in den Niederlanden

    NARCIS (Netherlands)

    Hondel, H. van den; Klamer, E.L.; Gulikers, J.; Polder, R.B.

    2015-01-01

    Die oberste niederländische Straßen- und Wasserbaubehörde (Rijkswaterstaat) hat im Hinblick auf die langfristige Instandhaltung ihrer Infrastruktureinrichtungen über 1500 Endverankerungsbereiche von Spannbetonbrückenträgern instandgesetzt und einer kathodischen Korrosionsschutzbehandlung (KKS)

  8. Intravenous administration of iodinated, non-ionic, low or isoosmolar contrast media: safety aspects; Intravenoese Anwendung von jodiertem, nichtionischem, nieder- bis isoosmolarem Kontrastmittel: Sicherheitsaspekte

    Energy Technology Data Exchange (ETDEWEB)

    Metz-Schimmerl, S.; Metz, V.; Schima, W.; Herold, C. [Universitaetsklinik fuer Radiodiagnostik und Ludwig Boltzmann-Institut fuer Klinische und Experimentelle Radiologie, Wien (Austria); Domanovits, H. [Universitaetsklinik fuer Notfallmedizin Wien, Wien (Austria)

    2002-01-01

    It iss the purpose of this review to provide information about the safe use of intravenously administered, iodinated, non-ionic, low or isoosmolar contrast media for radiological examinations, how to avoid adverse events, and how to react professionally in case of an anaphylactic reaction. Methods of prophylaxis and therapy for anaphylactic and chemotoxic effects of contrast media administration as well as absolute and relative contraindications are discussed. Medico-legal considerations of contrast agent administration, informed consent of patients, and methods of risk management for undesired contrast media reactions are considered in this article. Establishment of administration standards for contrast media is of tremendous importance to standardize radiological procedures. This basic radiological documentation is part of the institutional and individual legal safety management. (orig.) [German] Ziel dieses Artikels ist es, Kenntnisse zur sicheren Anwendung von intravenoes applizierten, jodierten, nichtionischen, nieder- bis isoosmolaren Roentgen-Kontrastmitteln zu vermitteln, um bei deren Verwendung unerwuenschte Wirkungen zu vermeiden oder im Falle eines anaphylaktischen Kontrastmittelzwischenfalls rasch und effektiv zu handeln. Neben Methoden der Verhuetung und Behandlung anaphylaktischer und chemotoxischer Wirkungen der Kontrastmittelgabe werden Einschraenkungen der Anwendung bei unterschiedlichen klinischen Bildern eroertert. Rechtliche Ueberlegungen zur Kontrastmittelanwendung, das Aufklaerungsgespraech und Praeventivmassnahmen zum Risiko-Management unerwuenschter Kontrastmittelwirkungen sind beruecksichtigt. Die Festlegung von Anwendungstandards fuer Kontrastmittel dient der Normierung medizinischen Vorgehens. Eine solche radiologische Basisdokumentation ist teil der institutionellen und individuellen rechtlichen Absicherung. (orig.)

  9. Von-Willebrand Disease Presenting as Intractable Epistaxis after Nasal Polypectomy

    Directory of Open Access Journals (Sweden)

    Jeong Jin Park

    2014-01-01

    Full Text Available Von-Willebrand disease (VWD is one of the platelet dysfunction disorders that results from a deficiency of Von-Willebrand factor, which is essential for hemostasis. VWD patients typically have normal laboratory results on screening for bleeding disorders. To suspect and diagnose VWD, a careful review of past medical history and laboratory tests is critical. A 59-year-old male patient presented with intractable nasal bleeding after nasal polypectomy. The bleeding was controlled by platelet transfusion, and he was later diagnosed with VWD.

  10. Methandiid-basierte Cabenkomplexe: Von ihrer Synthese und elektronischen Struktur zur Anwendung in Bindungsaktivierungsreaktionen und katalytischen Umsetzungen

    OpenAIRE

    Weismann, Julia

    2015-01-01

    Die vorliegende Arbeit beschäftigt sich mit der Anwendung des Sulfonyl-stabilisierten Methandiids 20-Li2 als Ligand in Übergangsmetallkomplexen. Dabei konnte 20-Li2 mit ver-schiedenen Übergangsmetallhalogeniden in Salzmetathesereaktionen umgesetzt werden. Insgesamt wiesen die synthetisierten Methandiid-basierten Komplexe flexible Bindungsverhältnisse bezüglich der MC-Bindung und unterschiedliche Koordinationsmodi der Sulfonyl-Gruppe auf, die die Stabilität und Reaktivität der Komplexe signif...

  11. S2k-Leitlinie zum Gebrauch von Präparationen zur lokalen Anwendung auf der Haut (Topika).

    Science.gov (United States)

    Wohlrab, Johannes; Staubach, Petra; Augustin, Matthias; Eisert, Lisa; Hünerbein, Andreas; Nast, Alexander; Reimann, Holger; Strömer, Klaus; Mahler, Vera

    2018-03-01

    Diese Leitlinie richtet sich an Assistenz- und Fachärzte der Dermatologie sowie an Kostenträger und politische Entscheidungsgremien. Die Leitlinie wurde im formellen Konsensusverfahren (S2k) von Dermatologen unter Einbindung von Apothekern erstellt. Die Leitlinie stellt allgemeine Aspekte der Pharmakokinetik sowie der regulatorischen Begrifflichkeiten dar. Es werden Empfehlungen zur Indikation von Magistralrezepturen sowie deren Qualitätssicherung gegeben. Die Bedeutung der galenischen Grundlagen und die Problematik bei einer Substitution gegeneinander verschiedener Grundlagen werden dargestellt. Die Leitlinie umfasst Kriterien zur Auswahl einer adäquaten Grundlage sowie spezifische Aspekte zur Therapieplanung. Die Leitlinie gibt Empfehlungen zum Management bei Unverträglichkeiten gegenüber Bestandteilen der Grundlagen oder Hilfsstoffe. © 2018 The Authors | Journal compilation © Blackwell Verlag GmbH, Berlin.

  12. Screening of additives for the production of ice pulp for application in normal cooling and freezing; Screening von Zusatzstoffen zur Herstellung von Eisbrei fuer die NK-/TK-Anwendung

    Energy Technology Data Exchange (ETDEWEB)

    Ruebeling, Jascha; Eiseler, Jens [Hochschule Karlsruhe - Technik und Wirtschaft (Germany). Inst. fuer Kaelte-, Klima- und Umwelttechnik

    2011-07-01

    The project investigated non-toxic additives for production of ice slurry. Ice slurry is an environment-friendly refrigerant that is increasingly used as a substitute for conventional refrigerants. In view of rising energy prices and an impending tax on climate-relevant refrigerants, ice slurry may soon be used for chilling of food in supermarkets. For this, ice slurry of about 0 C is required for normal cooling and of about -25 C for deep freezing. A very fine-grained, pumpable ice slurry is obtained with glucose as an additive, or with sodium chloride in eutectic concentration with small amounts of ethanol for deep freezing. Ethanol will refine the coarse crystal structure of the eutectic sodium chloride / water mixture and will also reduce the freezing point. Further, the method of primary crystallisation on a crystallised additive was developed. An industrial plant working by this principle will have less disturbances and wear during ice slurry production. [German] Die Projektarbeit befasste sich mit der Untersuchung lebensmittelvertraeglicher Additive zur Herstellung von Eisbrei. Eisbrei gilt als umweltfreundlicher Kaeltetraeger, der zunehmend in verschiedenen Bereichen zur Anwendung kommt und herkoemmliche Kaeltemittel ersetzen kann. Aufgrund steigender Energiekosten sowie einer eventuell anstehenden Besteuerung treibhauswirksamer Kaeltemittel, kann Eisbrei zukuenftig zur Kuehlung von Lebensmitteln in Supermaerkten verwendet werden. Dazu wird Eisbrei mit ca. 0 C fuer die Normalkuehlung, beziehungsweise mit ca. -25 C fuer die Tiefkuehlung benoetigt. Mit Glucose als Zusatzstoff laesst sich ein sehr feinkoerniger und damit pumpbarer Eisbrei fuer die Normalkuehlung erzeugen. Bei der Tiefkuehlung ist Natriumchlorid in einer eutektischen Konzentration mit geringen Mengen Ethanol empfehlenswert. Ethanol verfeinert die grobe Kristallstruktur des reinen eutektischen Natriumchlorid-Wasser-Gemisches und senkt den Gefrierpunkt. Des Weiteren wurde das Verfahren der

  13. Effects of platinum in biological systems - toxicology and pharmaceutical applications; Wirkungen von Platin in biologischen Systemen - Toxikologie und pharmazeutische Anwendung

    Energy Technology Data Exchange (ETDEWEB)

    Nachtigall, D [Fraunhofer-Institut fuer Toxikologie und Aerosolforschung, Hannover (Germany)

    1998-12-31

    The title of this lecture has intentionally been worded rather vaguely with ``biological systems`` to do justice to the fact that there are meanwhile extensive data available on diverse levels of the toxicology and structure-effect relationships of some platinum compounds. These range from epidemiological descriptions over toxicity studies to molecular biological reaction mechanisms. Any discussion on the toxicity of a substance implies that the substance poses a direct or indirect hazard to humans. In the case of platinum and its compounds there are three main categories of exposure: platinum production including workplaces in the platinum processing industries; clinical treatment with antineoplastic platinum-containing agents; and, finally, the environment, where platinum levels are known to be rising since some years. The association between these exposures becomes clear when one considers the platinum pollution caused by automobile catalytic converters, hospital effluents, and by platinum-containing industrial products in the widest sense. [Deutsch] Der Titel des Vortrages ist mit `biologischen Systemen` sehr allgemein gehalten, da ueber die Toxikologie und die Struktur-Wirkungsbeziehungen einiger Platinverbindungen auf den verschiedensten Ebenen umfangreiche Daten vorliegen. Diese reichen von epidemiologischen Beschreibungen ueber Toxizitaetsstudien bis hin zu molekularbiologischen Reaktionsmechanismen. Die Diskussion um die Toxizitaet von Substanzen impliziert immer die direkte oder indirekte Gefaehrdung des Menschen. Im Falle des Platins und seiner Verbindungen existieren drei wesentliche Expositionsbereiche: Die Platingewinnung sowie die Arbeitsplaetze in der Platin verarbeitenden Industrie, die klinische Behandlung mit antineoplastischen Platinwirkstoffen und schliesslich die Umwelt, in der seit einigen Jahren ansteigende Platinkonzentrationen verzeichnet werden. Die Verbindung zwischen diesen Bereichen wird deutlich, wenn man die Platinimmissionen durch

  14. Effects of platinum in biological systems - toxicology and pharmaceutical applications; Wirkungen von Platin in biologischen Systemen - Toxikologie und pharmazeutische Anwendung

    Energy Technology Data Exchange (ETDEWEB)

    Nachtigall, D. [Fraunhofer-Institut fuer Toxikologie und Aerosolforschung, Hannover (Germany)

    1997-12-31

    The title of this lecture has intentionally been worded rather vaguely with ``biological systems`` to do justice to the fact that there are meanwhile extensive data available on diverse levels of the toxicology and structure-effect relationships of some platinum compounds. These range from epidemiological descriptions over toxicity studies to molecular biological reaction mechanisms. Any discussion on the toxicity of a substance implies that the substance poses a direct or indirect hazard to humans. In the case of platinum and its compounds there are three main categories of exposure: platinum production including workplaces in the platinum processing industries; clinical treatment with antineoplastic platinum-containing agents; and, finally, the environment, where platinum levels are known to be rising since some years. The association between these exposures becomes clear when one considers the platinum pollution caused by automobile catalytic converters, hospital effluents, and by platinum-containing industrial products in the widest sense. [Deutsch] Der Titel des Vortrages ist mit `biologischen Systemen` sehr allgemein gehalten, da ueber die Toxikologie und die Struktur-Wirkungsbeziehungen einiger Platinverbindungen auf den verschiedensten Ebenen umfangreiche Daten vorliegen. Diese reichen von epidemiologischen Beschreibungen ueber Toxizitaetsstudien bis hin zu molekularbiologischen Reaktionsmechanismen. Die Diskussion um die Toxizitaet von Substanzen impliziert immer die direkte oder indirekte Gefaehrdung des Menschen. Im Falle des Platins und seiner Verbindungen existieren drei wesentliche Expositionsbereiche: Die Platingewinnung sowie die Arbeitsplaetze in der Platin verarbeitenden Industrie, die klinische Behandlung mit antineoplastischen Platinwirkstoffen und schliesslich die Umwelt, in der seit einigen Jahren ansteigende Platinkonzentrationen verzeichnet werden. Die Verbindung zwischen diesen Bereichen wird deutlich, wenn man die Platinimmissionen durch

  15. Klare Regeln - effiziente und effektive FMEA-Anwendung

    OpenAIRE

    Schloske, Alexander

    2014-01-01

    Der Vortrag beschreibt klare Regeln zur effizienten und effektiven FMEA-Anwendung. - Denkmodelle für die verschiedenen FMEA-Arten (System-FMEA, Konstruktions-FMEA, Prozess-FMEA) - Anwendungsbereiche und FMEA-Planung - Strukturierung von FMEAs - Funktionen, Produktmerkmale und Prozessmerkmale - Risikoanalyse - Maßnahmendefinition - Risikobewertung - Präsentation von FMEAs - FMEA als "lebendes Dokument".

  16. Entwicklung und Anwendung neuer NMR-Methoden: Orientierungsmedien zur Strukturbestimmung mit anisotropen Parametern und Metabonomics

    OpenAIRE

    Büchler, Silke

    2014-01-01

    Das Ziel dieser Arbeit war die Entwicklung und Anwendung neuer Orientierungsmedien zur Strukturbestimmung mit anisotropen Parametern, sowie die Etablierung von Metabonomics-Studien an Flüssigzellkulturen und Reispflanzen.

  17. [Kombinierte Anwendung von Strahlentherapie und adjuvanter Therapie mit einem Mistelextrakt (Viscum album L.) zur Behandlung des oralen malignen Melanoms beim Hund: Eine retrospektive Studie].

    Science.gov (United States)

    von Bodungen, Uta; Ruess, Katja; Reif, Marcus; Biegel, Ulrike

    2017-01-01

    Hintergrund: Orale maligne Melanome (OMM) des Hundes zeichnen sich durch schnelles Wachstum, lokale Invasion und hohe Metastasierungsraten aus. Extrakte auf Basis von Viscum album L. (VAE) werden zunehmend in der Krebstherapie sowohl in der Human- als auch in der Veterinärmedizin eingesetzt. Ziel unserer Studie war es zu untersuchen, inwieweit die adjuvante Therapie mit VAE eine therapeutische Option zur Behandlung von OMM ist. Besonderes Augenmerk galt dabei der Überlebenszeit und möglichen Nebenwirkungen. Tiere und Methoden: 26 Hunde mit OMM, die in einem der größten veterinäronkologischen Zentren der Schweiz allesamt eine Strahlentherapie erhielten (teilweise nach operativer Tumorresektion) wurden in die retrospektive Studie eingeschlossen: 18 Hunde wurden mit VAE behandelt (1 ml VAE (Iscador®) in ansteigenden Konzentrationen von 0,1 bis 20 mg/ml subkutan 3-mal pro Woche (VAE-Gruppe), 8 erhielten keine adjuvante Behandlung (Vergleichsgruppe). Wir verglichen die Größenentwicklung der OMM sowie die Überlebenszeit. Ergebnisse: Patienten mit Bestrahlung und adjuvanter VAE-Therapie zeigten mit 236 Tagen eine signifikant längere mediane Überlebenszeit im Vergleich zu Patienten mit Bestrahlung, aber ohne adjuvante VAE-Therapie (49 Tage; Log-Rank-Test: p = 0,0047). Die VAE-Therapie verlängerte die Überlebenszeit um mehr als zwei Drittel (Hazard Ratio (HR) = 0,30, 95%-Konfidenzintervall (KI) 0,11-0,86; p = 0,024), während ein höheres Tumorstadium gemäß UICC (Union internationale contre le cancer) einen statistischen Trend zur Verdopplung des Sterberisikos zeigte (UICC-Stadium III/IV vs. I/II: HR = 2,12, 95%-KI 0,88-5,12; p = 0,095). Zwei Patienten zeigten milde Nebenwirkungen während der VAE-Behandlung. Einer der beiden zeigte 1 Tag lang ein selbstlimitiertes Fieber, bei dem anderen Patienten reduzierten wir die Dosis von einem konzentrierteren zu einem weniger konzentrierten VAE (Serie 0) aufgrund von Müdigkeit, die daraufhin verschwand

  18. Screening und Quantifizierung organischer Spurenstoffe mittels UPLC-HRMS:Entwicklung von Methoden und Anwendung zur Unterscheidung historischer und aktueller Spurenstoffe in einem ehemaligen Rieselfeld

    OpenAIRE

    Wode, Florian

    2014-01-01

    Aufgrund zunehmender Wasserknappheit gewinnt die Nutzung von gereinigtem Abwasser (Klarwasser), bezeichnet als Water Reuse, weltweit an Bedeutung. Neben herkömmlichen chemischen und mikrobiologischen Parametern spielen organische Spurenstoffe zunehmend eine Rolle bei der Beurteilung der Wasserqualität, die über mögliche Nutzungsformen entscheidet. In dieser Arbeit wurde die Spurenstoffbelastung in Grund- und Oberflächenwasser eines ehemaligen Rieselfeldgebietes untersucht, in dem seit 2005 Kl...

  19. Small specimen test results and application of advanced models for fracture mechanics assessment of RPV integrity; Ergebnisse von Kleinproben und Anwendung von Modellansaetzen zur bruchmechanischen Bewertung der RDB-Integritaet

    Energy Technology Data Exchange (ETDEWEB)

    Keim, Elisabeth; Huemmer, Matthias [AREVA NP GmbH (Germany); Hoffmann, Harald [VGB (Germany); Nagel, Gerhard [e-on Kernkraft (Germany); Kuester, Karin [VENE (Germany); Koenig, Guenter; Ilg, Ulf [EnBW (Germany); Widera, Martin [RWE (Germany); Rebsamen, Daniel [KKW Goesgen (Germany)

    2008-07-01

    For the RPV (reactor pressure vessel) integrity assessment the transferability of specimen test results to components is of main importance. The international project TIMES (transferability of fracture toughness of irradiated materials to components and structures) is focussed on the transferability of fracture mechanical characteristics of irradiated materials to components or structures, in order to allow the quantification of differences between sample and component characteristics based on experiments and calculations. The studies were performed for the brittle and brittle-ductile regions of the material characteristics using specimens from original RPV materials in different conditions. Based on case studies the consequence of a component assessment with postulated defects are shown when specimen-related materials properties are used. Since it is not possible to prove the transferability for an RPV in detail, component-similar effects were investigated that allow in combination with numerical modelling to quantify the safety margin. Samples and experimental procedures were developed that simulated the real component situation. The effects of crack depth and multiaxial loads, relevant for real components, were investigated with these samples. A micromechanical model was developed based on the weakest link theory and the statistical failure probability; this model is used for the prediction of fracture toughness of samples and components with defects. For a component with postulated defects the safety margin was assessed using different methodologies, based on standard fracture mechanical samples, taking into account component specific aspects. [German] Fuer die Bewertung der RDB-Integritaet ist die Uebertragbarkeit von Probenkennwerten auf Bauteile von grosser Bedeutung. Dazu wurde das Projekt ''TIMES'' - ein internationales Projekt zur Uebertragbarkeit von Bruchzaehigkeitskennwerten von bestrahlten Materialien auf Komponenten und Strukturen - durchgefuehrt, um

  20. IFRS 8 OPERATING SEGMENTS: Eine Untersuchung der erstmaligen Anwendung in der Schweiz

    OpenAIRE

    Meyer, C; Weiss, S

    2010-01-01

    Seit dem 1. Januar 2009 sind kotierte IFRS-Anwender verpflichtet, eine Segmentberichterstattung nach IFRS 8 zu erstellen. Anhand einer Analyse der Geschäftsberichte 2009 der an der SIX Swiss Exchange kotierten Unternehmen soll ein Überblick über die erstmalige Anwendung von IFRS 8 "Operating Segments" in der Schweiz gewonnen werden.

  1. Ribosomal studies on the 70S ribosome of E.coli by means of neutron scattering; Strukturuntersuchungen am 70S-Ribosom von E.coli unter Anwendung von Neutronenstreuung

    Energy Technology Data Exchange (ETDEWEB)

    Burkhardt, N. [GKSS-Forschungszentrum Geesthacht GmbH (Germany). Inst. fuer Werkstofforschung

    1997-12-31

    Neutronenstreuung liefern. Durch den Austausch des natuerlichen Wasserstoffs ({sup 1}H) gegen Deuterium ({sup 2}H) lassen sich Teilstrukturen des Komplexes fuer Neutronen kontrastieren und direkt in situ vermessen. Im Rahmen der vorliegenden Arbeit wurden solche deuterium-markierten Ribosomenpraeparate (E. coli) hergestellt und mit Neutronen analysiert. Die erforderlichen biochemischen Methoden wurden etabliert und zu einem allgemein anwendbaren Praeparationssystem zusammengefasst. Es koennen damit alle Komponenten des 70S-Ribosoms in beliebiger Kombination markiert werden. Auf der Grundlage einer systematischen Analyse der Protein- und RNA-Phasen konnte ein neues 70S-Ribosomenmodell entwickelt werden, das nicht nur die aeussere Form des Partikels beschreibt, sondern erstmals auch eine vermessene interne Protein-RNA-Verteilung und den Verlauf der Untereinheitengrenze angibt (Vierphasen-Modell; Aufloesung: 50 A). 70S-Ribosomenmodelle aus anderen Studien wurden anhand der gemessenen Streudaten beurteilt und gewichtet. Mit Hilfe einer neuen, besonders empfindlichen Neutronenstreutechnik, der Protonenspin-Kontrastvariation, gelang es ausserdem, einzelne markierte Proteine zu vermessen und zu lokalisieren. Mit den Positionen von S6 und S10 werden die ersten im 70S-Ribosom vermessenen Proteinschwerpunktskoordinaten vorgelegt. (orig.)

  2. Ribosomal studies on the 70S ribosome of E.coli by means of neutron scattering; Strukturuntersuchungen am 70S-Ribosom von E.coli unter Anwendung von Neutronenstreuung

    Energy Technology Data Exchange (ETDEWEB)

    Burkhardt, N [GKSS-Forschungszentrum Geesthacht GmbH (Germany). Inst. fuer Werkstofforschung

    1998-12-31

    Neutronenstreuung liefern. Durch den Austausch des natuerlichen Wasserstoffs ({sup 1}H) gegen Deuterium ({sup 2}H) lassen sich Teilstrukturen des Komplexes fuer Neutronen kontrastieren und direkt in situ vermessen. Im Rahmen der vorliegenden Arbeit wurden solche deuterium-markierten Ribosomenpraeparate (E. coli) hergestellt und mit Neutronen analysiert. Die erforderlichen biochemischen Methoden wurden etabliert und zu einem allgemein anwendbaren Praeparationssystem zusammengefasst. Es koennen damit alle Komponenten des 70S-Ribosoms in beliebiger Kombination markiert werden. Auf der Grundlage einer systematischen Analyse der Protein- und RNA-Phasen konnte ein neues 70S-Ribosomenmodell entwickelt werden, das nicht nur die aeussere Form des Partikels beschreibt, sondern erstmals auch eine vermessene interne Protein-RNA-Verteilung und den Verlauf der Untereinheitengrenze angibt (Vierphasen-Modell; Aufloesung: 50 A). 70S-Ribosomenmodelle aus anderen Studien wurden anhand der gemessenen Streudaten beurteilt und gewichtet. Mit Hilfe einer neuen, besonders empfindlichen Neutronenstreutechnik, der Protonenspin-Kontrastvariation, gelang es ausserdem, einzelne markierte Proteine zu vermessen und zu lokalisieren. Mit den Positionen von S6 und S10 werden die ersten im 70S-Ribosom vermessenen Proteinschwerpunktskoordinaten vorgelegt. (orig.)

  3. Fracture-mechanical analysis of metal/ceramic composites for applications in high-temperature fuel cells (SOFC); Bruchmechanische Untersuchung von Metall/Keramik-Verbunsystemen fuer die Anwendung in der Hochtemperaturbrennstoffzelle (SOFC)

    Energy Technology Data Exchange (ETDEWEB)

    Kuhn, Bernd Josef

    2008-08-25

    The author investigated the deformation and damage behaviour of soldered ceramic/metal joints in SOFC stacks, using thermochemical methods. Methods for analyzing sandwich systems and for mechanical characterization of joints were adapted and modified in order to provide fundamental understanding of the mechanical properties of soldered joints. [German] In dieser Arbeit wurde das Verformungs- und Schaedigungsverhalten von Keramik/ Metall-Loetverbindungen fuer SOFC-Stacks thermomechanisch untersucht. Verfahren zur Analyse von Schichtsystemen und fuer die mechanische Charakterisierung von Fuegeverbindungen wurden adaptiert und weiterentwickelt, um zu einem grundlegenden Verstaendnis der mechanischen Eigenschaften von Loetverbindungen zu gelangen.

  4. Nasal Physiology

    Science.gov (United States)

    ... Caregivers Contact ARS HOME ANATOMY Nasal Anatomy Sinus Anatomy Nasal Physiology Nasal Endoscopy Skull Base Anatomy Virtual Anatomy Disclosure ... Patient Education About this Website Font Size + - Home > ANATOMY > Nasal Physiology Nasal Anatomy Sinus Anatomy Nasal Physiology Nasal Endoscopy ...

  5. Nasal Anatomy

    Science.gov (United States)

    ... Caregivers Contact ARS HOME ANATOMY Nasal Anatomy Sinus Anatomy Nasal Physiology Nasal Endoscopy Skull Base Anatomy Virtual Anatomy Disclosure ... Size + - Home > ANATOMY > Nasal Anatomy Nasal Anatomy Sinus Anatomy Nasal Physiology Nasal Endoscopy Skull Base Anatomy Virtual Anatomy Disclosure ...

  6. Application of the inter-line PCR for the analyse of genomic rearrangements in radiation-transformed mammalian cell lines; Anwendung der Inter-Line PCR zur Analyse von genomischen Veraenderungen in strahlentransformierten Saeugerzellinien

    Energy Technology Data Exchange (ETDEWEB)

    Leibhard, S.; Smida, J. [Muenchen Univ. (Germany). Strahlenbiologisches Inst.; Eckardt-Schupp, F.; Hieber, L. [GSF-Inst. fuer Strahlenbiologie, Oberschleissheim (Germany)

    1996-12-31

    Repetitive DNA sequences of the LINE-family (long interspersed elements) that are widely distributed among the mammalian genome can be activated or altered by the exposure to ionizing radiation [1]. By the integration at new sites in the genome alterations in the expression of genes that are involved in cell transformation and/or carcinogenesis may occur [2, 3]. A new technique - the inter-LINE PCR - has been developed in order to detect and analyse such genomic rearrangements in radiation-transformed cell lines. From the sites of transformation- or tumour-specific changes in the genome it might be possible to develop new tumour markers for diagnostic purpose. (orig.) [Deutsch] Repetitive DNA-Sequenzen der LINE-Familie, die weit verbreitet im Genom von Saeugerzellen vorkommen, koennen durch Exposition mit ionisierender Strahlung aktiviert und veraendert werden [1]. Durch eine Neu- bzw. Reintegration an anderen Positionen im Genom kann es zu bedeutenden Veraenderungen im Genom der Zelle kommen. Die Expression von Genen, die bei den Prozessen der Zelltransformation bzw. der Karzinogenese beteiligt sind, kann dadurch veraendert werden [2, 3]. Mithilfe der von uns entwickelten Inter-LINE PCR und der anschliessenden Analyse der veraenderten Produktmuster nach gelelektrophoretischer Auftrennung koennen solche `genomic rearrangements` unter Beteiligung von LINE-Elementen untersucht und naeher charakterisiert werden. Durch Klonierung und Sequenzierung transformations- bzw. tumorspezifischer PCR-Produkte sollte es moeglich sein Tumormarker fuer diagnostische Zwecke zu entwickeln. Die Methode wurde fuer die Analyse von Zellen des Syrischen Hamster aufgebaut, sie ist jedoch universell fuer alle Saeuger anwendbar. (orig.)

  7. Planning, installation and use of ventilation systems for smoke and heat removal. Cooperation between architects, planners, and builder-owners; Planung, Einbau und Anwendung von Rauch- und Waermeabzugsanlagen. Zusammenwirken zwischen Architekt, Planer und Bauherr

    Energy Technology Data Exchange (ETDEWEB)

    Koschnitzki, K. [Duisburg Univ. (Germany). Inst. fuer Anlagenplanung und Systemtechnik; Berg, M. [e.t.s. Umwelt- und Sicherheitstechnik GmbH, Kleve (Germany)

    1998-05-01

    Cooperation between planners, builder-owners and technical experts is important for efficient fire prevention. This involves ventilation systems for smoke and heat removal as well as other safety components. Legal regulations must be implemented so as to obtain a fire protection concept with defined goals and to achieve maximum protection of furniture and inhabitants. (orig.) [Deutsch] Bei der Umsetzung von Brandschutzkonzepten in der Gebaeude- und Anlagenplanung ist das gemeinsame Vorgehen von Planer, Bauherr und Fachunternehmen von elementarer Wichtigkeit fuer ein ausgereiftes Sicherheitskonzept. Hierzu gehoeren Rauch- und Waermeabzugsanlagen und weitergehende sicherheitstechnische Komponenten. Auflagen und behoerdliche Bestimmungen sind so umzusetzen, dass ein Brandschutzkonzept mit definierten Schutzzielen entsteht. Fuer den Bauherrn soll ein maximaler Sachwert- und Personenschutz gewaehrleistet sein. (orig.)

  8. Hydrogen in motor car engineering. Production, storage, uses; Wasserstoff in der Fahrzeugtechnik. Erzeugung, Speicherung, Anwendung

    Energy Technology Data Exchange (ETDEWEB)

    Eichlseder, H.; Klell, M.

    2008-07-01

    The book presents a general outline of the various aspects of properties, production, storage and application of hydrogen at university level. The focus is on the thermodynamic aspects of hydrogen storage andon its applications in transportation and power supply. In particular, car engines and fuel cells are gone into, and the state of the art is outlined with reference to research projects of TU Graz university and HyCentA. Apart from the technical aspects, also the history and possible future trends are presented. [German] Dieses Buch bietet einen allgemeinen Ueberblick ueber die verschiedenen Aspekte von Eigenschaften, Erzeugung, Speicherung und Anwendung von Wasserstoff auf Hochschulniveau. Schwerpunkte liegen auf der Thermodynamik der Speicherung von Wasserstoff sowie auf der Anwendung in der Verkehrstechnik und in der Energietechnik. Speziell wird die Anwendung in der Verbrennungskraftmaschine und in der Brennstoffzelle behandelt, wobei mit Bezug auf Forschungsvorhaben an der TU Graz und dem HyCentA der aktuelle Stand der Technik fundiert dargestellt wird. Neben einer technischen Vertiefung werden auch die geschichtliche und die moegliche kuenftige Entwicklung angesprochen.

  9. Zur Materialfrage in der Implantatchirurgie des Deszensus: Vergleich zwischen Polypropylenvlies und dermaler porciner azellulärer Kollagenmatrix unter Berücksichtigung der Erfahrungen nach 7 Jahren Anwendung von Implantaten

    Directory of Open Access Journals (Sweden)

    Fischer A

    2004-01-01

    Full Text Available Ziel der Studie: Die Studie beschreibt Verwendung, Effektivität und Nebenwirkungen zwei verschiedener Implantate, die in der Senkungschirurgie verwendet werden und stellen die Ergebnisse in einen Zusammenhang mit den Erfahrungen mit anderen Implantaten seitens der Autoren und in der Literatur. Material und Methode: 180 Patientinnen mit verschiedenen Formen von Genitalprolaps werden mit Biomesh(R behandelt, 185 Patientinnen mit Pelvicol(R in der Zeit von Juli 2000 bis Dezember 2002. Die Ergebnisse werden verglichen. Ergebnisse: Die Verwendung von Implantaten ist häufig erforderlich, vor allen Dingen in Fällen eines stark zerstörten Beckenbodensystems oder bei Rezidiven. Die Verwendung von Netz-Implantaten in der Senkungschirurgie ist sicher, solange eine vernünftige Implantatstruktur zugrunde liegt. Beide in dieser Studie untersuchten Implantate erfüllen dies zufriedenstellend. Rezidiv- und Senkungszustände der benachbarten Kompartimente müssen getrennt ausgewertet werden, um eine Verwechslung zwischen einem schlechten Therapieergebnis (obwohl es eigentlich gut ist und Strukturschwächen in den (noch nicht behandelten Kompartimenten nicht in einem Topf zu werfen. Die Notwendigkeit einer Explantation, das Ausbilden von Abszessen oder die Abstoßungsreaktion wurden nur gesehen, wenn multifilamente mikroporöse Bänder oder entsprechend strukturiertes Nahtmaterial zur gleichen Zeit eingesetzt worden sind, oder wenn Blutergußbildung nicht durch subtile Hämostase während des Eingriffs unterdrückt werden konnte. Schlußfolgerung: Beide Materialien (Biomesh(R und Pelvicol(R liefern in der Verwendung bei implantatunterstützter Deszensus-Chirurgie gute Ergebnisse, gleich, wo sie auch eingesetzt werden. Es gibt keine signifikanten Unterschiede in der Effektivität oder in der Nebenwirkungsrate. Es bedarf nun der größer angelegten multizentrischen Studien, um alloplastisch unterstützte rekonstruktive Beckenbodenchirurgie nicht nur in den

  10. Development and application of dynamic MR-imaging for evaluation of perfusion changes in rectal carcinoma during a course of radiotherapy in clinical use. Preliminary results; Entwicklung und Anwendung dynamischer MRT-Messungen zur Evaluierung von Perfusionsveraenderungen bei Rektumkarzinomen unter Bestrahlung in der klinischen Routine. Erste Ergebnisse

    Energy Technology Data Exchange (ETDEWEB)

    Vries, A. de; Griebel, J.; Gneiting, T.; Hoflehner, J.; Brandl, M.; Lukas, P. [Leopold-Franzens-Univ. Innsbruck (Austria). Universitaetsklinik fuer Strahlentherapie - Radioonkologie; Judmaier, W.; Kremser, C.; Schocke, M.; Aichner, F. [Leopold-Franzens-Univ. Innsbruck (Austria). Inst. fuer Magnetresonanztomographie; Peer, S.; Rettl, G. [Leopold-Franzens-Univ. Innsbruck (Austria). Universitaetsklinik fuer Radiodiagnostik I; Oefner, D. [Leopold-Franzens-Univ. Innsbruck (Austria). Universitaetsklinik fuer Chirurgie; Debbage, P. [Leopold-Franzens-Univ. Innsbruck (Austria). Inst. fuer Histologie und Embryologie

    1999-11-01

    procedures. (orig.) [German] Ziel: Entwicklung und Anwendung dynamischer Magnetresonanztomographiemessungen zur Erhebung von Perfusionsparametern bei Rektumkarzinomen unter Bestrahlung in der klinischen Routine. Patienten und Methode: Bei Rektumkarzinompatienten (n=8), die sich einer praeoperativen kombinierten Radiochemotherapie unterzogen, wurden Perfusionsdaten erhoben. An einem 1,5-Tesla-Ganzkoerperkernspintomographen wurden ultraschnelle T1-Mapping-Sequenzen zum Erhalt von T1-Maps mit Intervallen von 14 und 120 Sekunden implementiert. Die Messzeit der dynamischen Messungen betrug 40 Minuten. Die Messschicht (Schichtdicke 5 mm) wurde so gewaehlt, dass sowohl Tumor als auch arterielle Gefaesse dargestellt wurden. Gadolinium-DTPA-(Gd-DTPA-)Konzentrations-Zeit-Kurven wurden nach einem prolongierten Bolus im arteriellen Blut und im Tumor berechnet. Die angewendete Methode erlaubte eine raeumliche Aufloesung von 2x2x5 mm und eine zeitliche Aufloesung von 14 Sekunden. Die Messdaten wurden vor und in konstanten Intervallen waehrend Therapie erhoben. Ergebnisse: Die raeumliche und zeitliche Aufloesung der T1-Maps war ausreichend, um Areale mit unterschiedlicher Kontrastmittelkinetik innerhalb des Tumors zu erfassen sowie die grossen Beckenarterien sicher zu identifizieren. Bei sechs Patienten konnten Gd-DTPA-Konzentrationskurven im Tumor unter Therapie erhoben werden. Der Perfusionsindex (Pi) versus Strahlendosis zeigte eine signifikante Zunahme in der ersten oder zweiten Woche der Bestrahlung, bevor er entweder kontinuierlich absank oder nach anfaenglichem Abfall einen erneuten Anstieg aufwies. Der durchschnittliche Pi-Ausgangswert betrug 0,16 ({+-}0,049), das durchschnittliche Pi-Maximum war 0,23 ({+-}0,058). Die relativen Perfusionsveraenderungen betrugen zwischen 20 und 83%. Schlussfolgerung: Unsere Ergebnisse zeigen, dass sich die verwendete Methode zur Erfassung von Perfusionsparametern unter Bestrahlung eignet und in der klinischen Routine anwendbar ist. In der Zukunft

  11. Anwendung stabiler Isotope zur Beschreibung des mikrobiellen Abbaus organischer Schadstoffe in kontaminierten Aquiferen

    OpenAIRE

    Vieth, Andrea

    2003-01-01

    Der mikrobielle in-situ Abbau organischer Schadstoffe ist mit einer Änderung der Isotopenverhältnisse (12C/13C; H/D) verbunden. Das Ausmaß der Isotopenfraktionierung ist abhängig von der initialen biochemischen Reaktion und variiert mit der Größe des Substratmoleküls bzw. der Anzahl der Kohlenstoff- bzw. Wasserstoffatome. Für die Anwendung dieses Isotopenkonzepts zur Beschreibung des mikrobiellen Abbaus von Schadstoffen im Grundwasser muss ausgeschlossen werden können, dass andere Prozesse ei...

  12. Water quality and management - the use of models for the estimation of the hazard potential for groundwater by organic pollutants in solid waste; Gewaesserguete und Wasserwirtschaft - Anwendung von Modellen zur Abschaetzung der Grundwassergefaehrdung durch organische Stoffe aus Reststoffen

    Energy Technology Data Exchange (ETDEWEB)

    Klein, M.

    2000-08-31

    In this study the deterministic leaching model PELMO was extended in order to consider two additional transport processes (fast transport via the macro porous flow system without equilibrium conditions with respect to sorption, and transport of pollutants in the soil water bound to humic substances). The extended model was implemented into the stochastic estimation model MCPELMO 2.0. The new development has built in 22 leaching scenarios based on a combination of the German soil regions map (12 soil regions) and 9 representative weather stations. As daily temperature and precipitation data over a period of 30 years were available the influence of climatic fluctuations on the percaloate concentrations could be considered. In parallel to the model development nomograms were calculated based on the algorithms of MCPELMO 2.0 making it possible to estimate concentrations in leachate also graphically. The results of the MCPELMO 2.0 simulations were compared with comprehensive simulations over a period of 1000 years performed with the computer model PELMO. The analysis showed that the screening model MCPELMO 2.0 that was orders of magnitude faster than PELMO was nevertheless able to estimate concentrations close to PELMO for most of the substances. It was additionally concluded that the results of the estimation model behave conservative compared to the comprehensive simulations: MCPELMO is often slightly overestimating pollutant concentrations in the percolate. Only for pollutants having KOC values above 5000 L/kg and DT50 numbers above 2000 days MCPELMO was estimating lower concentrations in the percolate than PELMO. (orig.) [German] In diesem Vorhaben wurde das deterministische Versickerungsmodell PELMO um zwei zusaetzliche Transportprozesse erweitert (schneller Stofftransport ueber das Makroporensystem ohne Einstellung von Sorptionsgleichgewichten, sowie Transport von Stoffen im Bodenwasser gebunden an Huminsaeuren) und das erweiterte Modell in das stochastische

  13. Development and prototypical application of analysis methods for complex anion mixtures in waters and heavy metal organyls in sediments; Entwicklung und prototypische Anwendung von Analysenverfahren fuer komplexe Anionengemische in Waessern und Schwermetallorganylen in Sedimenten. Schlussbericht

    Energy Technology Data Exchange (ETDEWEB)

    Anders, B.; Knoechel, A.; Potgeter, H.; Staub, S.; Stocker, M.

    2002-07-01

    When it comes to assessing the hazards emanating from heavy pollutants in waters mere elemental analysis provides too little information. Due to the great differences in toxicity and mobility it is important to know more about the exact species in question. This is particularly true of heavy metals that form stable organyls, specifically As, Pb, Sn and Hg, but also of alkylated arsenic acids, which need to be measured in complex anion mixtures. The purpose of the present project was to develop robust, powerful analysis methods and thus overcome the existing deficit in reliable analysis methods for these substances. An important approach in this connection is the use of coupled chromatography and detection systems for separation and analysis. [German] Hinsichtlich der von einer Schwermetallbelastung in Gewaessern ausgehenden Gefahren liefert die reine Elementanalytik nur unzureichende Aussagen. Aufgrund der grossen Unterschiede in Toxiditaet und Mobilitaet ist die Kenntnis der jeweils vorliegenden Spezies bedeutungsvoll. Dies gilt in besonderem Masse fuer die stabile Organyle bildenden Schwermetalle As, Pb, Sn und Hg sowie die alkylierten Arsensaeuren, die es innerhalb komplexer Anionengemische zu bestimmen gilt. Hinsichtlich ihrer sicheren Bestimmung bestehen methodische Defizite, die das vorliegende Projekt durch die Entwicklung robuster, nachweisstarker Analysenverfahren zu beseitigen versucht. Grosse Bedeutung kommt dabei gekoppelten Systemen aus Chromatographie und Detektion als Trenn- und Bestimmungsmethode zu. (orig.)

  14. Hydrogen in motor car engineering. Production, storage, use. 3. rev. ed.; Wasserstoff in der Fahrzeugtechnik. Erzeugung, Speicherung, Anwendung

    Energy Technology Data Exchange (ETDEWEB)

    Eichlseder, Helmut [Technische Univ., Graz (Austria). Inst. fuer Verbrennungskraftmaschinen und Thermodynamik; Klell, Manfred [HyCentA Research GmbH, Graz (Austria)

    2012-07-01

    The book outlines the various aspects of properties, generation, storage and uses of hydrogen. The focus is on the thermodynamics of hydrogen storage and on its applications in vehicle engineering and energy engineering. Using the example of current research projects of TU Graz university and HyCentA, the state of the art is presented in some detail. The sections on fuel cells for automotive power generation, hydrogen/methane mixtures and legal and safety aspects have been updated. [German] Dieses Buch bietet einen allgemeinen Ueberblick ueber die verschiedenen Aspekte von Eigenschaften, Erzeugung, Speicherung und Anwendung von Wasserstoff. Schwerpunkte liegen auf der Thermodynamik der Speicherung von Wasserstoff sowie auf der Anwendung in der Fahrzeugtechnik und in der Energietechnik. Mit Bezug zu Forschungsvorhaben an der TU Graz und dem HyCentA wird der aktuelle Stand der Technik fundiert dargestellt. Aktualisiert und ergaenzt wurden vor allem die Abschnitte ueber Brennstoffzellen zur Stromerzeugung fuer Elektroantriebe, ueber Gemische aus Wasserstoff und Methan sowie ueber Fragen von Recht und Sicherheit.

  15. New findings for the use of NMR- and computer tomography for gauging the potential of drilling fluids to cause damage to rocks; Neue Erkenntnisse bei der Anwendung von NMR- und Computertomografie-Methoden im Rahmen der Bewertung des Traegerschaedigungspotentiales von Bohrfluessigkeiten

    Energy Technology Data Exchange (ETDEWEB)

    Zwaag, C. van der [Reservoir Labs. AS, Trondheim (Norway); Stallmach, F. [Univ. Leipzig (Germany). Fakultaet fuer Physik und Geowissenschaften; Hanssen, J.E. [MI/Anchor Drilling Fluids AS, Stavanger (Norway); Soergaard, E. [Norsk Hydro AS, Bergen (Norway); Toennesen, R. [Saga Petroleum ASA, Stavanger (Norway)

    1998-12-31

    Polyanionic cellulose, xanthane and ppolyglycole are standard additives for water-based drilling fluids. These are added to drilling liquids to control water loss, provide viscosity and inhibit slating. Filtration losses, which are unavoidable when drilling, cause scavenging polymers to penetrate the area around the drilled hole. This causes a number of different reactions with the surrounding rocks and may ultimately have a permanent influence on the flow conditions of hydrocarbons. The study mentioned above aimed at determining the damage potential of these additives. [Deutsch] Polyanionische Cellulose, Xanthan und Polyglykol sind uebliche Zusatzstoffe von wasserbasischen Bohrspuelungen. Diese werden Bohrfluessigkeiten zur Wasserverlustkontrolle, zur Viskositaetsbildung und zur Schieferinhibierung zugesetzt. Die beim Bohrprozess unvermeidlichen Filtrationsverluste fuehren dazu, dass Spuelungspolymere beim Bohren in den Bohrlochnahbereich eindringen. Die Beschaffenheit dieser Stoffe fuehrt nach dem Eindringen zu unterschiedlichen Reaktionen mit dem Traegergestein. Diese koennen letzten Endes einen dauerhaften Einfluss auf die Zuflussbedingungen von Kohlenwasserstoffen haben. Das Ziel der vorliegenden Studie war es, das Traegerschaedigungspotential der obengenannten Spuelungszusaetze zu charakterisieren. (orig.)

  16. Nasal Cancer

    Science.gov (United States)

    ... the way to your throat as you breathe. Cancer of the nasal cavity and paranasal sinuses is ... be like those of infections. Doctors diagnose nasal cancer with imaging tests, lighted tube-like instruments that ...

  17. Speziation von Gadolinium-MRT-Kontrastmitteln in Umweltmatrizes

    OpenAIRE

    Lindner, Uwe

    2017-01-01

    Gd-Kontrastmittel werden in der Medizin für die Magnetresonanztomographie (MRT) benötigt, um einen besseren Bildkontrast zu erzielen. Nach der Anwendung gelangen diese Arzneimittel über das Abwasser in die Klärwerke und von dort in die jeweiligen anliegenden Oberflächengewässer. Somit wird es notwendig, den Verbleib der Gd-MRT-Kontrastmittel in der Umwelt zu verfolgen und aufzuklären. In dieser Arbeit werden für die Analyse von Umweltproben Methoden zur Speziesanalytik von Gd-Kontrastmitteln ...

  18. Status reports on the development and application of acoustic emission analysis. Proceedings; Statusberichte zur Entwicklung und Anwendung der Schallemissionsanalyse. Beitraege

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2009-07-01

    This proceedings-CD comprises 20 papers presented at the 17. Kolloquium Schallemission (Acoustic Emission Colloquium) at Bad Schandau. The following subjects were discussed: 1. Acoustic emission analysis of tensile tests on standard test specimens of different wood materials; 2. Application of pattern recognition methods for damage analyses of fibre-reinforced plastics; 3. Acoustic emission analysis for measuring crack growth in finned armor steel under dynamic load; 4. Acoustic emission analysis with zonal sound location: Test objects, test results and evaluation of acoustic emission signals; 5. Acoustic emission analysis in overall fatigue testing of a wind rotor blade; 6. Laboratory methods for assessing the sensitivity of acoustic emission sensors; 7. Acoustic emission analysis in burst tests of cast aluminium casings; 8. Visualization of acoustic emission localizations; 9. Threshold-independent and complete recording of characteristics and wave forms of transient and continuous acoustic emission; 10. Characterization of wide-band acoustic emission sensors; 11. Handling of large data volumes in acoustic emission analysis, a contribution to the development of algorithms; 12. Acoustic emission analysis and ultrasonic analysis for the characterization of crack networks in saline rock. One of the papers is available as a separate record in this database. [German] Diese Tagungs-CD enthaelt 20 Vortraege, die auf dem 17. Kolloquium Schallemission in Bad Schandau gehalten wurden. Die Themen waren: 1. Schallemissionsanalyse von Zugversuchen an Standardpruefkoerpern aus unterschiedlichen Holzwerkstoffen; 2. Anwendung von Mustererkennungsverfahren zur Schadensanalyse in faserverstaerkten Kunststoffen; 3. Anwendung der Schallemissionsanalyse zur Ermittlung des Risswachstums bei schwingender Beanspruchung von geripptem Bewehrungsstahl; 4. Schallemissionspruefung mit zonaler Ortung Pruefobjekte, Pruefergebnisse und Nachbewertung von Schallemissionssignalen; 5

  19. Separate treatment of turbid water from sludge treatment; Separate Behandlung von Truebwaessern aus der Schlammbehandlung

    Energy Technology Data Exchange (ETDEWEB)

    Boehm, B.; Arnold, E.; Wilderer, P.A. [Technische Univ. Muenchen, Garching (Germany). Lehrstuhl und Pruefamt fuer Wasserguete- und Abfallwirtschaft

    1999-07-01

    In semi-technical investigations, discontinuous activated sludge processes and biofilm processes for the nitrification of sludge water were compared. Both processes were found to be equally suited for this application. (orig.) [German] In halbtechnischen Untersuchungen wurden diskontinuierlich betriebene Belebtschlamm- und Biofilmverfahren zur Nitrifikation von Schlammwaessern gegenuebergestellt. Es zeigte sich, dass beide Verfahren gleichermassen fuer diese Anwendung geeignet sind. (orig.)

  20. Nasal polyps

    Science.gov (United States)

    ... shrink polyps, and can reduce swelling and nasal congestion. The effect lasts a few months in most ... this procedure, your doctor uses a thin, lighted tube with instruments at the end. The tube is ...

  1. Application of the EC pressure equipment directive in the gas industry; Die Anwendung der EG-Druckgeraeterichtlinie in der Gaswirtschaft

    Energy Technology Data Exchange (ETDEWEB)

    Bueschel, K. [Deutscher Verein des Gas- und Wasserfaches e.V., Bonn (Germany); John, M. [Karlsruhe Univ. (T.H.) (Germany). DVGW-Forschungsstelle am Engler-Bunte-Institut; Wasser, U. [Bundesverband der Deutschen Gas- und Wasserwirtschaft e.V., Bonn (Germany)

    2000-07-01

    The EC Pressure Equipment Directive primarily concerns that broad range of equipment that falls under the Equipment Safety Act and its regulations on pressure vessels, boilers etc. Meanwhile, however, the mainstream view is that also some equipment of the gas industry is affected although its pipeline systems have been excluded from the Directive. The interpretation of the Directive must take into account this background in order to reach satisfactory conclusions in the actual application of the Directive to the components of the gas industry. (orig.) [German] Die EG-Druckgeraeterichtlinie betrifft primaer jenes grosse Geraetespektrum, das unter das Geraetesicherheitsgesetz und dessen Verordnungen zu Druckbehaeltern, Dampfkesseln etc. faellt. Inzwischen herrscht jedoch die Meinung vor, dass auch bestimmte Anlagenteile der Gaswirtschaft erfasst werden, obwohl deren Rohrleitungssysteme von der Richtlinie ausgenommen worden sind. Die Auslegung der Richtlinie muss diesen Hintergrund beachten, um zu befriedigenden Aussagen bei ihrer konkreten Anwendung auf die Komponenten der Gaswirtschaft zu gelangen. (orig.)

  2. Combined application of numerical simulation models and fission tracks analysis in order to determine the history of temperature, subsidence and lifting of sedimentary basins. A case study from the Ruhr Coal basin inWest Germany; Die kombinierte Anwendung numerischer Simulationsmodelle und Spaltspurenuntersuchungen zur Entschluesselung der Temperatur-, Subsidenz- und Hebungsgeschichte von Sedimentbecken - Ein Fallbeispiel aus dem Ruhrkohlenbecken Westdeutschlands

    Energy Technology Data Exchange (ETDEWEB)

    Karg, H. [Forschungszentrum Juelich (Germany). Inst. fuer Erdoel und organische Geochemie; Littke, R. [RWTH Aachen (Germany); Bueker, C. [Univ. Bern (Switzerland). Inst. fuer Geologie

    1998-12-31

    The Ruhr Coal basin is one of the globally best known sedimentary basins. According to classical, established the Ruhr Basin is a typical foreland molasse basins. The thermal history (heating and cooling) and the structural and sedimentary development since the formation of the basin, i.e. subsidence and lifting and erosion are of the first importance for the potential formation of hydrocarbons. In order to quantify these processes, two-dimensional numerical simulation models (based on geological and seismological sections) of the Ruhr basin were developed from which one could conclude the heat flow at the time of maximum basin depth after variscis orogenesis, maximum temperatures of individual strata sections and thickness of eroded strata. The PetroMod program package of the company IES/Juelich was used for these analyses. Finite-element-grids enable mathematican mapping and reconstruction of complex geological structures and processes. The models on temperature history are calibrated by comparing measured and calculated carbonification (vitrinite reflection) data. (orig./MSK). [Deutsch] Das Ruhrkohlenbecken stellt weltweit eines der am besten erforschten Sedimentbecken dar. Nach klassischen und etablierten Beckenmodellen kann das Ruhrbecken als typisches Vorlandmolassebecken angesehen werden. Besonders relevant fuer die potentielle Bildung von Kohlenwasserstoffen sind in erster Linie die thermische Geschichte (Aufheizung und Abkuehlung) sowie die strukturelle und sedimentaere Entwicklung seit der Beckenbildung, sprich Versenkungs-, Hebungs- und Erosionsprozesse. Um solche Prozesse zu quantifizieren, wurden im Ruhrbecken zweidimensionale (d.h. auf der Grundlage von geologischen und seismischen Sektionen) numerische Simulationsmodelle entwickelt, die Aufschluss ueber Waermefluesse zur Zeit der maximalen Beckeneintiefung im Anschluss an die variszische Orogenese, erreichte Maximaltemperaturen einzelner Schichtglieder sowie die Maechtigkeit erodierter Schichten im

  3. Effects of chemicals on terrestrial ecosystems exhibiting different types of stability. Pt. 2. Application of fractal geometry to structural analysis in terrestrial ecotoxicology; Auswirkungen von Chemikalien auf terrestrische Oekosysteme unterschiedlichen Stabilitaetstyps. T. 2. Anwendung der fraktalen Geometrie zur Strukturanalyse in der terrestrischen Oekotoxikologie

    Energy Technology Data Exchange (ETDEWEB)

    Bornkamm, R.; Darius, F.

    1995-04-01

    terrestrischer Oekosysteme auf anthropogene Fremdstoffe messbar und interpretationsfaehig sind, wurden zwei Vegetationstypen getestet, deren Arten sich primaer in ihrer Verbreitungsstrategie (ueber Samen bzw. ueber Knospen) unterscheiden, die hier aber auch von Pflanzen unterschiedlicher Klassen aufgebaut werden. Als Chemikalien wurden zwei niedrig dosierte Herbizide (2.4.5-T und Atrazin) verwendet, die auf vielen wichtigen Ebenen des Pflanzenorganismus Wirkungen ausloesen. Es konnten an Staerke und Dauer ganz unterschiedliche Reaktionen in den beiden Systemen beobachtet werden. Die Frage aufgrund dieser Beobachtungen war, welche generellen Aussagen sich ueber Ausmass und Reversibilitaet dieser Eingriffe bzw. Veraenderungen fuer die getesteten Systeme treffen lassen. Hierzu mussten die vermuteten Vorgaenge innerhalb der Pflanzengemeinschaften in ein Modell gefasst und interpretiert werden. Mit dem vorgestellten Modell ist es moeglich, den Weg von der individuellen Strassenreaktion zur komplexen Systemantwort nachzuverfolgen. Verschiedene Simulationsergebnisse konnten direkt mit Reaktionen getesteter realer Oekosysteme verglichen werden, oder fuehrten zu Hypothesen, die sich experimentell pruefen liessen. Im Bereich der terrestrischen Oekotoxikologie sind u.E. neben den (fuer die laufenden Zulassungsverfahren) notwendigen Datensammlungen aus empirischen Substanzpruefungen auch weitere Grundlagenforschungen wichtig. Denn eine Vorhersage ueber die konkrete Entwicklung eines bestimmten Oekosystems (mit oder ohne anthropogenem `Stess`) scheint auf Grund theoretischer Argumente wenig realistisch, bei ausreichender Kenntnis aber von typbezogenen Systemreaktionen und Einfluss von Randbedingungen koennen immerhin Aussagen ueber die Wahrscheinlichkeit von Effekten erwartet werden. (orig.)

  4. Nasal encephaloceles

    NARCIS (Netherlands)

    Hoving, Eelco W.

    2000-01-01

    Nasal encephaloceles can be divided into frontoethmoidal and basal encephaloceles. Both conditions are very rare, but frontoethmoidal encephaloceles show a relatively high incidence (1:5,000) in Southeast Asia. The pathogenesis of encephaloceles may be explained by a disturbance in separation of

  5. Application of C-arm computed tomography in cardiology; Kardiale Anwendung der C-Arm-Computertomographie

    Energy Technology Data Exchange (ETDEWEB)

    Rieber, J. [Klinikum der Ludwig-Maximilians-Universitaet Muenchen, Campus Innenstadt, Abteilung fuer Kardiologie, Medizinische Poliklinik, Muenchen (Germany); Rohkohl, C. [Friedrich-Alexander-Universitaet Erlangen-Nuernberg, Lehrstuhl fuer Mustererkennung, Department Informatik, Erlangen (Germany); Siemens AG, Healthcare Sector, Forchheim, Forchheim (Germany); Lauritsch, G. [Siemens AG, Healthcare Sector, Forchheim, Forchheim (Germany); Rittger, H. [Krankenhaus Coburg, Abteilung fuer Kardiologie, Coburg (Germany); Meissner, O. [Siemens AG, Healthcare Sector, Forchheim, Forchheim (Germany); Klinikum der Ludwig-Maximilians-Universitaet Muenchen, Institut fuer Klinische Radiologie, Muenchen (Germany)

    2009-09-15

    C-arm computed tomography is currently being introduced into cardiac imaging and offers the potential for three-dimensional imaging of the cardiac anatomy within the interventional environment. This detailed view is necessary to support complex interventional strategies, such as transcutaneous valve replacement, interventional therapy of atrial fibrillation, implantation of biventricular pacemakers and assessment of myocardial perfusion. Currently, the major limitation of this technology is its insufficient temporal resolution which limits the visualization of fast moving parts of the heart. (orig.) [German] Durch die Entwicklung der C-Arm-Computertomographie- (CACT-)Angiographie ist es erstmals moeglich, waehrend einer Herzkatheteruntersuchung eine detaillierte dreidimensionale Darstellung der kardialen Anatomie zu erhalten. Derartige zusaetzliche Informationen koennten die Durchfuehrung der immer komplexer werdenden Strategien der interventionellen Kardiologie wirkungsvoll unterstuetzen. Hierzu zaehlen u. a. der transkutane Klappenersatz, die interventionelle Behandlung von Vorhofflimmern, die Implantation biventrikulaerer Schrittmacher sowie die Beurteilung der Myokardperfusion. Die derzeit groesste Limitation dieser Methode ist die relativ geringe zeitliche Aufloesung, die aufgrund der Bewegung des Herzens die Anwendung dieser Technologie einschraenkt. (orig.)

  6. Biofuels - Properties and application experience; Biokraftstoffe - Eigenschaften und Erfahrungen bei der Anwendung

    Energy Technology Data Exchange (ETDEWEB)

    Schmiedel, H.P.

    2002-12-01

    The European Union wants to promote the use of renewable raw materials also in the traffic sector in order to meet the internationally committed reduction of carbon dioxide emissions. At the same time a new market shall be created for farming and jobs shall be secured. Fatty acid methyl esters in the diesel market and ethanol and ethyl tertiary butyl ether (ETBE) in gasoline are discussed as compounds that can be produced from renewable raw materials and be applied as fuels in the short term. This literature survey deals with the extent of CO{sub 2} / greenhouse gas emission reductions, the availability of biofuels and summarizes the economical and technical experiences obtained so far with their application. The use of pure vegetable oils, dimethylether and pyrolysis oil is also briefly covered. (orig.) [German] Die EU will auch im Verkehrsbereich den Einsatz nachwachsender Rohstoffe foerdern, um die international zugesagte Reduzierung der Kohlendioxid-Emissionen zu erreichen. Gleichzeitig sollen damit der Landwirtschaft ein neuer Markt eroeffnet und Arbeitsplaetze gesichert werden. Fettsaeuremethylester fuer den Dieselbereich sowie Ethanol und Ethyltertiaerbutylether (ETBE) fuer Ottokraftstoff werden als Verbindungen genannt, die aus nachwachsenden Rohstoffen gewonnen und kurzfristig als Kraftstoff eingesetzt werden koennen. Die vorliegende Literaturstudie beleuchtet den Umfang der CO{sub 2}- bzw. Klimagasreduktion, die Verfuegbarkeit der Biokraftstoffe und fasst die oekonomischen und technischen Erfahrungen zusammen, die bisher in ihrer Anwendung erhalten wurden. Die Nutzung von reinen Pflanzenoelen, Dimethylether und Pyrolyseoel wird gestreift. (orig.)

  7. The integrity concept and its implementation; Das Integritaetskonzept und seine praktische Anwendung

    Energy Technology Data Exchange (ETDEWEB)

    Roos, E.; Herter, K.H.; Schuler, X. [Stuttgart Univ. (Germany). MPA; Koenig, G. [EnBW Kernkraft GmbH, Neckarwestheim (Germany)

    2008-07-01

    , dass fuer die Gewaehrleistung von Bruchausschluss die Beherrschung der Ursachen von im Betrieb moeglichen Schaedigungsmechanismen von entscheidender Bedeutung ist. Im Gegensatz dazu stellt das ''Integritaetskonzept'' als Umsetzung des Basissicherheitskonzepts unter Beruecksichtigung der jeweiligen anlagenspezifischen Voraussetzungen ein geschlossenes Gesamtkonzept dar, das der Notwendigkeit einer mehrstufigen Absicherung und ''laufender'' Aktualisierung Rechnung traegt. Das Integritaetskonzept ist Bestandteil des Alterungsmanagements fuer mechanische Komponenten und Systeme. Am Beispiel der Speisewasserleitung innerhalb Containment der Anlage GKN 1 wird dessen praktische Anwendung zum Nachweis der Integritaet aufgezeigt. (orig.)

  8. Bestimmung der optimalen Array-Apertur für die Ultraschallprüfung von faserverstärkten Kunststoffen

    OpenAIRE

    Kurras, Martin

    2017-01-01

    Für die zerstörungsfreie Prüfung von Kohlenstofffaserverbundwerkstoffen (CFK) wird häufig die Ultraschallprüfung verwendet. Neben dem klassischen Ultraschallverfahren findet dabei auch die Phased Array Technologie Anwendung. Hierbei wird zwischen zwei Verfahren unterschieden: dem handelsüblichen Phased Array oder Conventional Phased Array (CPA) und dem tomographischen Sampling Phased Array (SPA). Der Einsatz von Phased Arrays im Zusammenhang mit Linear-Scan-Technik und das sich daraus ergeben...

  9. Kombinierte elektromagnetische Vollwellen- und strahlbasierte Simulationen von Fahrzeugantennen in virtuellen Testfahrten

    OpenAIRE

    Mocker-Henning, Marina

    2016-01-01

    In dieser Arbeit werden elektromagnetische Untersuchungen von Fahrzeugantennen für verschiedene Dienste in virtuellen Testfahrten unter Anwendung einer Kombination aus Vollwellen- und Ray Tracing- Methoden simulativ durchgeführt. Es werden verschiedene Vollwellen- Lösungsverfahren und -Lösermethoden vorgestellt und verglichen. Für die Berechnung der Ausbreitung elektromagnetischer Wellen im mobilen Szenario wird ein Ray Tracing Programm entwickelt, das für eine hohe Berechnungsgeschwindigkeit...

  10. Nasal Wash Treatment

    Science.gov (United States)

    ... Medications Alternative Therapies Nasal Wash Treatment Nasal Wash Treatment Make an Appointment Ask a Question Refer Patient The Centers for Disease Control (CDC) guidelines for preparing water used in a nasal wash are listed below. Many ...

  11. Advances in radiographic NDI of pipe systems; Fortschritte bei der Durchstrahlungspruefung von Rohrleitungssystemen

    Energy Technology Data Exchange (ETDEWEB)

    Morgner, W. [NSQ HAUK, Ludwigshafen (Germany); Hauk, T. [NSQ HAUK, Ludwigshafen (Germany); Tschachlov, V. [NSQ HAUK, Tomsk (Russian Federation)

    1995-12-31

    The paper discusses the application of a small-sized betatron and its operational parameters, and its uses for very small angle tomography of medium-filled pipes or a thick weld. Other aspects discussed are the handling of large numbers of X-ray images by means of an X-ray manipulator, film digitalization, and data management of imaging data. (orig./MM) [Deutsch] Dieser Beitrag behandelt die Anwendung eines Kleinbetatrons und seiner Leistungsparameter, damit durchgefuehrte Durchstrahlungspruefungen an mediumgefuellten Rohren und eine an einer dicken Schweissnaht realisierte Wenigwinkeltomographie. Bezueglich der Beherrschung einer Grosszahl von Roentgenaufnahmen wird ueber einen Roentgenmanipulator, die Filmdigitalisierung und das Datenmanagement von Bilddaten berichtet. (orig./MM)

  12. Gerbstoffe aus Potentilla officinalis wirken entzündungshemmend im UV-Erythem-Test und bei Anwendung auf atopischer Haut.

    Science.gov (United States)

    Hoffmann, Julia; Wölfle, Ute; Schempp, Christoph M; Casetti, Federica

    2016-09-01

    Das Rhizom von Potentilla officinalis (PO) ist reich an Gerbstoffen und wird traditionell zur äußerlichen Behandlung von Entzündungen der Haut und der Schleimhäute verwendet. Ziel der vorliegenden Arbeit war die Bestätigung der antiinflammatorischen Eigenschaften von PO mittels eines UV-Erythem-Tests und einer klinischen Anwendungsstudie bei atopischer Haut. Die antiinflammatorische Wirkung eines PO-Extrakts (standardisiert auf 2 % Trockensubstanz) wurde in einer prospektiven, randomisierten, placebokontrollierten Doppelblindstudie mit 40 gesunden Erwachsenen im UV-Erythem-Test im Vergleich zu 1 % Hydrocortisonacetat untersucht. Im Rahmen einer prospektiven nicht kontrollierten Studie wurde die Wirkung und Verträglichkeit der 2 % PO-Creme an zwölf Erwachsenen und zwölf Kindern mit atopischer Haut nach Anwendung über zwei Wochen in einem definierten Testareal anhand eines Teil-SCORAD untersucht. Zusätzlich wurde die Beeinflussung der Hautrötung im Testareal photometrisch gemessen. Im UV-Erythem-Test zeigte die PO-Creme eine signifikante Reduktion des Erythemindex im Vergleich zum Vehikel. Die antiinflammatorische Wirkung des Verums entsprach der der 1 % Hydrocortisonacetat-Creme. Die klinische Studie bei Atopikern zeigte eine signifikante Abnahme des Teil-SCORAD und des Erythems im Testareal. Es wurden keine Unverträglichkeitsreaktionen beobachtet. PO als 2%ige Zubereitung besitzt entzündungshemmende Eigenschaften und ist wirksam und gut verträglich auf atopischer Haut. © 2016 Deutsche Dermatologische Gesellschaft (DDG). Published by John Wiley & Sons Ltd.

  13. Nasal chondromesenchymal hamartoma with no nasal symptoms.

    LENUS (Irish Health Repository)

    Uzomefuna, Vincent

    2012-01-01

    The authors present a case of nasal chondromesenchymal hamartoma (NCMH) in an 8-year-old boy with a 4-month history of frontal headache and no symptoms of nasal obstruction, rhinorrhoea or postnasal drip. An ENT examination as well as ophthalmology assessment presented normal results. CT scan showed a lesion involving the sphenoid and ethmoid sinuses. The patient had an endoscopic resection of the lesion that was confirmed histologically to be a NCMH. Though NCMH is known to present usually in infants with obstructing nasal mass, an unusual presentation of a patient with throbbing headache without any nasal symptoms is reported here.

  14. Application of soil data in climate research; Anwendung von Bodendaten in der Klimaforschung

    Energy Technology Data Exchange (ETDEWEB)

    Kaufmann-Boll, Carolin; Kappler, Wolfgang; Lazar, Silvia [ahu AG Wasser - Boden - Geomatik, Aachen (DE)

    2011-10-15

    The German Strategy for Adaptation to Climate Change was adopted in 2008. The implementation of the strategy requires reliable data and time series on the long-term changes in soil condition and soil functions. Soil monitoring and soil survey are essential data bases for this purpose. In Germany there are permanently established monitoring programmes with representative locations and repeated soil surveys based on a regular grid of sites. The different programmes vary in respect to harmonization regarding agreed principles between the participating institutions. Information on soil measuring data is currently heterogeneous and distributed at many locations. Particularly the provision of (meta-)data should be improved. Here you can find the exceptional quality of BOKLIM. It evaluates the suitability of soil data for climate research across the different measuring programmes in Germany. The most important nation-wide and permanently operating programmes of soil monitoring and soil survey were taken into account. The main aspects were the changes in soil condition due to climate change. As a result, the programmes provide a variety of valuable data to assess the effects of climate change on soils. Depending on the problem and the resulting requirements, the data are suitable (1) for the long-term monitoring of changes in soil condition, (2) for detailed process studies and measurements at representative locations, e.g. for the calibration and validation of predictive models, and (3) for use in model scenarios predicting changes in soil condition. However, it is necessary to coordinate the programmes of soil monitoring and soil survey with the focus on precise questions. The programmes have to be optimized at certain points to improve for issues of climate change and adaptation. In addition to the evaluation of soil data, a first concept for an efficient data provision and data use was created. Recommendations for next steps to coordinate and optimize future monitoring and survey activities and for data provision are advised to the relevant competent institutions and actors. Further research needs were identified. The recommendations aim at improving the interaction between climate change and soil conditions. They can also be taken up for other research fields such as soil protection aspects or biodiversity strategy aspects. (orig.)

  15. Application of soil data on adaptation of climate; Anwendung von Bodendaten bei der Klimaanpassung

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2010-05-15

    Within the workshop of the Federal Environment Agency (Dessau-Rosslau, Federal Republic of Germany) at 20th to 30th September, 2009 in Dessau (Federal Republic of Germany), the following lectures were held: (1) Action plan adaptation - Adaptation measures and their verifiability on the basis of soil data (K. Mattern); (2) Legal background of the provision of metadata (H. Ginzky); (3) Which soil data are necessary? Requirements of Evaluation of the impact of climatic change and adaptation (W. Eckelmann); (4) Which soil data are present? Chances, deficits and recommendations for action (C. Kaufmann); (5) Instruments for providing metadata (W. Kappler); (6) Project TERENO - Soil atmosphere interactions induced by land use changes as a result of global change (H. Bogena, T. Puetz, H. Vereecken); (7) Further development and implementation of an European forest monitoring sysem (O. Granke); (8) Survey of the state of soil in agriculture and forestry (S. Schobel, C. Siebner); (9) Requirements on soil data from the view of the European Community (L. Montanarella); (10) Resume, view into the future, experiences with the market (F. Makeschin, H.G. Meiners, J. Mathews).

  16. From clay bricks to deep underground storage; vom lehmziegel bis zum tiefenlager -- anwendung von ton

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2012-05-15

    This booklet issued by the Swiss National Cooperative for the Disposal of Radioactive Waste NAGRA takes a look at the use of clay strata for the storage of radioactive wastes in deep-lying repositories. First of all, a geological foray is made concerning the history of the use of clay and its multifarious uses. The characteristics of clay and its composition are examined and its formation in the geological past is explained. In particular Opalinus clay is looked at and the structures to be found are discussed. The clay's various properties and industrial uses are examined and its sealing properties are examined. Also, Bentonite clay is mentioned and work done by Nagra and co-researchers is noted.

  17. Nasal septal hematoma

    Science.gov (United States)

    ... medlineplus.gov/ency/article/001292.htm Nasal septal hematoma To use the sharing features on this page, please enable JavaScript. A nasal septal hematoma is a collection of blood within the septum ...

  18. Kostenorientiertes Controlling von E-Learning-Plattformen mit dem TCO-Konzept - Methodische Grundlagen, Softwareunterstützung und Entwicklungsperspektiven

    Directory of Open Access Journals (Sweden)

    Jan vom Brocke

    2007-07-01

    Full Text Available Zur administrativen Unterstützung von Lehr- und Lernprozessen werden E-Learning-Plattformen eingesetzt, die auf der Grundlage des Internet Funktionen zur Distribution von Lehr- und Lernmaterialien und zur Kommunikation zwischen Lehrenden und Lernenden anbieten. Zahlreiche wissenschaftliche Beiträge und Marktstudien beschäftigen sich mit der multikriteriellen Evaluation dieser Softwareprodukte zur informatorischen Fundierung strategischer Investitionsentscheidungen. Demgegenüber werden Instrumente zum kostenorientierten Controlling von E-Learning-Plattformen allenfalls marginal thematisiert. Dieser Beitrag greift daher das Konzept der Total Cost of Ownership (TCO auf, das einen methodischen Ansatzpunkt zur Schaffung von Kostentransparenz von E-Learning-Plattformen bildet. Aufbauend auf den konzeptionellen Grundlagen werden Problembereiche und Anwendungspotenziale für das kostenorientierte Controlling von LMS identifiziert. Zur softwaregestützten Konstruktion und Analyse von TCO-Modellen wird das Open Source-Werkzeug TCO-Tool eingeführt und seine Anwendung anhand eines synthetischen Fallbeispiels erörtert. Abschließend erfolgt die Identifikation weiterführender Entwicklungsperspektiven des TCO-Konzepts im Kontext des E-Learning. Die dargestellte Thematik ist nicht nur von theoretischem Interesse, sondern adressiert auch den steigenden Bedarf von Akteuren aus der Bildungspraxis nach Instrumenten zur informatorischen Fundierung von Investitions- und Desinvestitionsentscheidungen im Umfeld des E-Learning.

  19. Nasal Lobular Capillary Hemangioma

    Directory of Open Access Journals (Sweden)

    Prashant Patil

    2013-01-01

    Full Text Available Nasal lobular capillary hemangioma is a rare benign tumor of the paranasal sinuses. This lesion is believed to grow rapidly in size over time. The exact etiopathogenesis is still a dilemma. We discuss a case of nasal lobular capillary hemangioma presenting with a history of epistaxis. Contrast enhanced computed tomography of paranasal sinuses revealed an intensely enhancing soft-tissue mass in the left nasal cavity and left middle and inferior meati with no obvious bony remodeling or destruction. We present imaging and pathologic features of nasal lobular capillary hemangioma and differentiate it from other entities like nasal angiofibroma.

  20. Nasal Glioma: Case report

    Directory of Open Access Journals (Sweden)

    Ozgur Surmelioglu

    2011-02-01

    Full Text Available Nasal gliomas are rare, benign, congenital tumors that are thought to be result of abnormality in embryonic development. Three types of clinical presentations have been recognized; extranasal, intranasal and combined. Clinically, these masses are non-pulsatile, gray or purple lesions that obstruct the nasal cavity and cause deformity extranasaly. Histologically, they are made up of astrocytic cells, fibrous and vascular connective tissue that is covered with nasal respiratory mucosa. Treatment of the nasal glioma requires a multidisciplinary approach including an radiologist, neurosurgeon and otorhinolaryngologist. Radiological investigation should be performed to describe intracranial extension. In this case, a 2 years old boy with nasal mass that was diagnosed as nasal glioma is reported. . [Cukurova Med J 2011; 36(1.000: 34-36

  1. Nasal Glioma: Case report

    Directory of Open Access Journals (Sweden)

    Ozgur Surmelioglu

    2011-03-01

    Full Text Available Nasal gliomas are rare, benign, congenital tumors that are thought to be result of abnormality in embryonic development. Three types of clinical presentations have been recognized; extranasal, intranasal and combined. Clinically, these masses are non-pulsatile, gray or purple lesions that obstruct the nasal cavity and cause deformity extranasaly. Histologically, they are made up of astrocytic cells, fibrous and vascular connective tissue that is covered with nasal respiratory mucosa. Treatment of the nasal glioma requires a multidisciplinary approach including an radiologist, neurosurgeon and otorhinolaryngologist. Radiological investigation should be performed to describe intracranial extension. In this case, a 2 years old boy with nasal mass that was diagnosed as nasal glioma is reported. . [Cukurova Med J 2011; 36(1: 34-36

  2. Simulation of pendulum shock experiments on a passenger car front axle; Simulation von Pendelschlagversuchen an einer PKW-Vorderachse

    Energy Technology Data Exchange (ETDEWEB)

    Sporer, L.; Witt, R.; Muehlbauer, R. [BMW Group, Muenchen (Germany)

    2001-07-01

    The contribution describes the development and application of a method for simulating loads resulting from misuse on car body components. The development of the method and its validation by experiments are described, and its application in the development of the BMW-5 series is gone into. [German] Der Beitrag beschreibt die Entwicklung und Anwendung einer Methode zur Simulation von Missbrauchsbelastungen an Fahrwerkskomponenten. Im ersten Abschnitt ist die systematische Entstehung der Methode und die Absicherung der Simulationsergebnisse durch Ersatzversuche dargestellt. In den folgenden Abschnitten steht die Anwendung der Methode in der Fahrwerksentwicklung bei BMW am Beispiel der Vorderachse der aktuellen 5-er Baureihe im Vordergrund. Das Deformationsverhalten einzelner Lenker bzw. die Schadenskette an der gesamten Achse werden sowohl fuer den seitlichen, als auch fuer den frontalen Pendelschlag aufgezeigt. (orig.)

  3. Cyanocobalamin Nasal Gel

    Science.gov (United States)

    ... to supply extra vitamin B12 to people who need unusually large amounts of this vitamin because they are pregnant or have certain diseases. ... Cyanocobalamin nasal gel will supply you with enough vitamin B12 only as ... it regularly. You may need to use cyanocobalamin nasal gel every week for ...

  4. Nasal dermoid sinus cyst.

    Science.gov (United States)

    Cauchois, R; Laccourreye, O; Bremond, D; Testud, R; Küffer, R; Monteil, J P

    1994-08-01

    Nasal dermoid sinus cyst is one of the diagnoses of midline nasal masses in children. This retrospective study analyzes the various theories regarding the origin of this congenital abnormality, the differential diagnosis, and the value of magnetic resonance imaging, as well as the various surgical options available.

  5. Health risks associated with inhaled nasal toxicants

    NARCIS (Netherlands)

    Feron, VJ; Arts, JHE; Kuper, CF; Slootweg, PJ; Woutersen, RA

    2001-01-01

    Health risks of inhaled nasal toxicants were reviewed with emphasis on chemically induced nasal lesions in humans, sensory irritation, olfactory and trigeminal nerve toxicity, nasal immunopathology and carcinogenesis, nasal responses to chemical mixtures, in vitro models, and nasal dosimetry- and

  6. Objective Measure of Nasal Air Emission Using Nasal Accelerometry

    Science.gov (United States)

    Cler, Meredith J.; Lien, Yu-An, S.; Braden, Maia N.; Mittleman, Talia; Downing, Kerri; Stepp, Cara, E.

    2016-01-01

    Purpose: This article describes the development and initial validation of an objective measure of nasal air emission (NAE) using nasal accelerometry. Method: Nasal acceleration and nasal airflow signals were simultaneously recorded while an expert speech language pathologist modeled NAEs at a variety of severity levels. In addition, microphone and…

  7. Verbesserung der OCR in digitalen Sammlungen von Bibliotheken

    Directory of Open Access Journals (Sweden)

    Konstantin Baierer

    2016-11-01

    Full Text Available Möglichkeiten zur Verbesserung der automatischen Texterkennung (OCR in digitalen Sammlungen insbesondere durch computerlinguistische Methoden werden beschrieben und bisherige PostOCR-Verfahren analysiert. Im Gegensatz zu diesen Möglichkeiten aus der Forschung oder aus einzelnen Projekten unterscheidet sich die momentane Anwendung von OCR in der Bibliothekspraxis wesentlich und nutzt das Potential nur teilweise aus. Possibilities for improving the optical character recognition (OCR in digital collections in particular by using computationally linguistical methods are described and previous PostOCR-techniques are analyzed. On contrast to these methods from the research and single projects, the current use of OCR in library practice differs essentially and does use its potential only partially.

  8. A Rare Nasal Bone Fracture: Anterior Nasal Spine Fracture

    Directory of Open Access Journals (Sweden)

    Egemen Kucuk

    2014-04-01

    Full Text Available Anterior nasal spine fractures are a quite rare type of nasal bone fractures. Associated cervical spine injuries are more dangerous than the nasal bone fracture. A case of the anterior nasal spine fracture, in a 18-year-old male was presented. Fracture of the anterior nasal spine, should be considered in the differential diagnosis of the midface injuries and also accompanying cervical spine injury should not be ignored.

  9. Nasal capillariasis in a dog

    International Nuclear Information System (INIS)

    King, R.R.; Greiner, E.C.; Ackerman, N.; Woodard, J.C.

    1990-01-01

    A five-year-old dog was evaluated for chronic nasal discharge. Nasal infection caused by Capillaria aerophila was diagnosed by identification of adult nematodes and eggs in the nasal flush sediment and by nasal biopsy samples and eggs in faecal flotations. Reinfection occurred following treatment with fenbendazole and ivermectin, probably because of a contaminated housing area

  10. Logfile-Analysen zur Evaluation der didaktischen Einbettung von CSCL-Systemen - am Beispiel der CommSy-Nutzung in offenen Seminaren

    Directory of Open Access Journals (Sweden)

    Martin Klein

    2005-02-01

    Full Text Available In unserem Beitrag evaluieren wir die didaktische Einbettung einer CSCL-Anwendung anhand von Logfile-Analysen. Dazu betrachten wir exemplarisch die Nutzung des webbasierten Systems CommSy in einer projektorientierten Lehrveranstaltung, die wir als offenes Seminar charakterisieren. Wir erzielen zwei Ergebnisse: (1 Wir geben Hinweise zur Gestaltung des Nutzungskontexts eines CSCL-Systems sowie zur Unterstützung seiner anfänglichen und kontinuierlichen Nutzung. (2 Wir beschreiben die Analyse von Nutzungsanlässen und -mustern sowie von NutzerInnentypen anhand von Logfiles. Dabei können Logfile-Analysen zur Validierung weiterer Evaluationsergebnisse dienen, sind selbst jedoch nur in Kombination mit zusätzlichen Informationen zum Nutzungskontext interpretierbar.

  11. Simulation, evaluation and optimization of hydrological storage systems; Simulation, Bewertung und Optimierung von Betriebsregeln fuer wasserwirtschaftliche Speichersysteme

    Energy Technology Data Exchange (ETDEWEB)

    Lohr, H.

    2001-07-01

    The investigation focused on controlled hydrological storage system. Existing operating schedules and new control options were analyzed, classified and generalized in order to obtain a standardized terminology and operating concept. This generalized approach will do away with the need for system-specific analyses and models for every single new system. [German] Der Schwerpunkt dieser Arbeit ist der wasserwirtschaftliche Betrieb von regelbaren Speichersystemen und ihre Simulation. Dabei bestand das Ziel darin, bestehende Betriebsplaene und neue praktikable Steuerungsmoeglichkeiten zu analysieren, zu klassifizieren und so zu generalisieren, dass eine einheitliche Terminologie und Konzeption zum Betrieb von Speichern entstand. Dieses Konzept erlaubt, in Verbindung mit den Prinzipien aus der Modellierung von Flussgebieten, verschieden strukturierte Speichersysteme mit unterschiedlichsten Steuerungsvorschriften abzubilden. Damit erhaelt man den Vorteil einer generalisierten Anwendung im Gegensatz zu einer fuer den speziellen Fall konzipierten und nicht uebertragbaren Einzelloesung. Als Folge davon entfaellt das systemspezifische, je nach Aufgabenstellung neu zu entwerfende und zu programmierende Einzelmodell. (orig.)

  12. PEM-fuel cells for mobile application. Sub task: development of electrocatalysts. Final report; PEM-Brennstoffzelle fuer mobile Anwendung. Teilprojekt: Katalysatorenentwicklung. Abschlussbericht

    Energy Technology Data Exchange (ETDEWEB)

    Starz, K A

    1999-01-01

    PEM fuel cells are gaining increasing importance for use in automotive application. The goal of the research program reported here was to develop the basic technology and components for PEMFC stacks for use in transport applications. The sub-task of Degussa was to develop improved electrocatalysts for PEMFC single cells and stacks. The technical objectives of the research project were met. Electrocatalysts, characterized by a high Pt-dispersion, high surface area and excellent activity, were developed. With this material, considerable progress was made to reduce the total platinum loading of PEMFC cells and stacks to about 0,5 mgPt/cm{sup 2}. With this value, the goal of the program (<0,8 mg/cm{sup 2}) was significantly surpassed. Additionally, higher power densities of >0.4 W/cm{sup 2} were achieved at Degussa for hydrogen/air and reformate/air operation of the PEMFC. A CO-tolerant anode electrocatalyst, exhibiting a CO-tolerance of up to 100 ppm CO, enables the operation of PEMFC stacks with on-board generated methanol reformate. The performance of the new electrocatalyst materials was verified by DaimlerChrysler in a PEMFC demonstration stack at the end of the program. (orig.) [Deutsch] PEM-Brennstoffzellen gewinnen fuer die mobile Anwendung immer mehr an Bedeutung. Im Rahmen des hier beschriebenen Leitprojektes sollten die Basistechnologien fuer den Einsatz der PEM-Brennstoffzelle im mobilen Bereich (Elektrotraktion) entwickelt werden. Das Teilprojekt der Degussa befasst sich mit der Entwicklung von verbesserten Elektrokatalysatoren fuer PEM-Brennstoffzellenstacks. Die technischen Arbeitsziele des Vorhabens wurden erreicht. So konnten Elektrokatalysatoren bereitgestellt werden, die sich durch eine hohe Pt-Dispersion, eine grosse Pt-Oberflaeche sowie eine sehr gute Aktivitaet auszeichnen. Mit diesen Elektrokatalysatoren gelang es, die Platinbeladung der PEM-Elektroden (Anode und Kathode) erheblich abzusenken. Mit einer Gesamtplatinbeladung von 0,5 mg/cm{sup 2

  13. Practical event analysis; Durchfuehrung von Ereignisanalysen in der Praxis

    Energy Technology Data Exchange (ETDEWEB)

    Scheuring, R. [Bayernwerk Kernenergie GmbH - Kernkraftwerk Grafenrheinfeld (Germany)

    1999-04-01

    The paper explains the systematic approaches and practical aspects of evaluation of NPP operating reports and implementation of identified remedial action for enhancing the safety in terms of human, organisational, and technology factors. The procedures adopted for the Grafenrheinfeld nuclear power station (KKG) serve as an example. (orig./CB) [German] Ein wichtiger Bestandteil zur Erhaltung und Fortentwicklung des Sicherheitsniveaus ist das Lernen aus der Erfahrung. Hierzu wiederum ist ein systematisches Vorgehen zur Vermeidung von Fehlern und Behebung von Schwachstellen menschlicher, technischer und organisatorischer Natur unabdingbare Voraussetzung. Die Anwendung einer umfassenden Auswertemethodik beinhaltet - die Erfassung und Informationsweitergabe externer und interner Vorkommnisse und Erfahrungen - eine systematische Analyse/Auswertung - eine konsequente Umsetzung der Abhilfemassnahmen unter Einbeziehen aller betroffenen Organisationseinheiten. Wie erfolgt die Umsetzung dieser Vorgaben in die Praxis? Im Kernkraftwerk Grafenrheinfeld (KKG) ist die Auswertung von externen und internen Betriebserfahrungen als Aufgabe im Betriebshandbuch (BHB) 'Personelle Betriebsorganisation' vorgegeben und im Detail im Sinne der Ablauforganisation im Qualitaetssicherungshandbuch in Qualitaetssicherungsanweisungen (QSA) beschrieben. (orig.)

  14. von Neumann Morgenstern Preferences

    DEFF Research Database (Denmark)

    Vind, Karl

    von Neumann Morgenstern utility is generalized to von Neumann Morgenstern preferences. The proof is an application of simple hyperplane theorems......von Neumann Morgenstern utility is generalized to von Neumann Morgenstern preferences. The proof is an application of simple hyperplane theorems...

  15. von Neumann Morgenstern Preferences

    DEFF Research Database (Denmark)

    Vind, Karl

    2000-01-01

    von Neumann Morgenstern utility is generalized to von Neumann Morgenstern preferences. The proof is an application of simple hyperplane theorems......von Neumann Morgenstern utility is generalized to von Neumann Morgenstern preferences. The proof is an application of simple hyperplane theorems...

  16. Nicotine Nasal Spray

    Science.gov (United States)

    ... with a smoking cessation program, which may include support groups, counseling, or specific behavior change techniques. Nicotine nasal ... and pharmacist what prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking or ...

  17. Determination of the deposition of polycyclic aromatic hydrocarbons (PAHs) to soil at Scheyern and Kirchheim near Munich; Bestimmung der Eintraege von polyzyklischen aromatischen Kohlenwasserstoffen (PAHs) an den Standorten Scheyern und Kirchheim bei Muenchen

    Energy Technology Data Exchange (ETDEWEB)

    Krainz, A; Wiedenmann, M; Maguhn, J [GSF-Forschungszentrum fuer Umwelt und Gesundheit Neuherberg (Germany). Inst. fuer Oekologische Chemie

    1998-12-31

    Task force 1, ``Analysis of the exposure of soils``, carried out comprehensive and site-specific measurements of the transfer of environmental chemicals into soil by means of the example of s-triazines and polycyclic aromatic hydrocarbons (PAHs). This work was in four parts: a: Determination of PAH nuisance concentrations in selected sites (Juelich, Scheyern, Bad Lauchstaedt); b: Measurement of wet deposition, development and use of methods for the determination of dry deposition; c: Statements regarding large-area PAH transfer into soil in Germany; d: Modelling of the rates of dry deposition. (orig.) [Deutsch] Aufgabe der Arbeitsgruppe 1 `Belastungsanalyse von Boeden`: Flaechendeckende sowie standortbezogene Erfassung der Eintraege von Umweltchemikalien am Beispiel der s-Triazine und PAHs. a: Bestimmung der Immissionskonzentrationen von PAHs an den Schwerpunktstandorten (Juelich, Scheyern, Bad Lauchstaedt) b: Messung der Nassen Deposition, Entwicklung und Anwendung von Methoden zur Bestimmung der Trockenen Deposition c: Aussagen ueber flaechendeckende Eintraege von PAHs in der Bundesrepublik d: Modellierung der Trockendepositionsraten. (orig.)

  18. Determination of the deposition of polycyclic aromatic hydrocarbons (PAHs) to soil at Scheyern and Kirchheim near Munich; Bestimmung der Eintraege von polyzyklischen aromatischen Kohlenwasserstoffen (PAHs) an den Standorten Scheyern und Kirchheim bei Muenchen

    Energy Technology Data Exchange (ETDEWEB)

    Krainz, A.; Wiedenmann, M.; Maguhn, J. [GSF-Forschungszentrum fuer Umwelt und Gesundheit Neuherberg (Germany). Inst. fuer Oekologische Chemie

    1997-12-31

    Task force 1, ``Analysis of the exposure of soils``, carried out comprehensive and site-specific measurements of the transfer of environmental chemicals into soil by means of the example of s-triazines and polycyclic aromatic hydrocarbons (PAHs). This work was in four parts: a: Determination of PAH nuisance concentrations in selected sites (Juelich, Scheyern, Bad Lauchstaedt); b: Measurement of wet deposition, development and use of methods for the determination of dry deposition; c: Statements regarding large-area PAH transfer into soil in Germany; d: Modelling of the rates of dry deposition. (orig.) [Deutsch] Aufgabe der Arbeitsgruppe 1 `Belastungsanalyse von Boeden`: Flaechendeckende sowie standortbezogene Erfassung der Eintraege von Umweltchemikalien am Beispiel der s-Triazine und PAHs. a: Bestimmung der Immissionskonzentrationen von PAHs an den Schwerpunktstandorten (Juelich, Scheyern, Bad Lauchstaedt) b: Messung der Nassen Deposition, Entwicklung und Anwendung von Methoden zur Bestimmung der Trockenen Deposition c: Aussagen ueber flaechendeckende Eintraege von PAHs in der Bundesrepublik d: Modellierung der Trockendepositionsraten. (orig.)

  19. Life cycle assessment of alternative sewage sludge disposal methods; Oekobilanz von Klaerschlammentsorgungsalternativen

    Energy Technology Data Exchange (ETDEWEB)

    Fehrenbach, H. [Institut fuer Energie- und Umweltforschung (ifeu), Heidelberg (Germany)

    1994-10-01

    At present there are three principal options for sewage sludge disposal in use or under discussion: agricultural utilisation - landfilling - cold pretreatment prior to disposal or utilisation (e.g., composting or fermentation) - thermal pretreatment prior to disposal or utilisation (e.g., monocombustion, co-combustion, pyrolysis, gasification). 10% of sewage sludge is currently combusted, 60% is landfilled, and 30% is used for agriculture. The ifeu Institute has carried out several studies which examine and compare the environmental impact of sewage sludge disposal options. [Deutsch] Zur Entsorgung bzw. Verwertung von Klaerschlamm stehen derzeit drei grundsaetzliche Optionen in Anwendung oder werden diskutiert: - Landwirtschaftliche Verwertung - Deponierung - kalte Vorbehandlung vor Deponierung oder Verwertung (z.B. Kompostierung oder Vergaerung) - thermische Vorbehandlung vorn Deponierung oder Verwertung (z.B. Mono- oder Mitverbrennung, Pyrolyse, Vergasung). Verbrannt werden gegenwaertig etwa 10%, 60% deponiert und 30% landwirschaftlich verwertet. Das ifeu-Institut hat in verschiedenen Arbeiten die Umweltauswirkungen von Klaerschlammentsorgungsoptionen untersucht und gegenuebergestellt. (orig./SR)

  20. Nasal septum extramedullary plasmacytoma

    Directory of Open Access Journals (Sweden)

    Belić Branislav

    2013-01-01

    Full Text Available Introduction. Plasmacytomas are malignant tumors characterized by abnormal monoclonal proliferation of plasma cells. They originate in either bone - solitary osseous plasmacytoma, or in soft tissue - extramedullary plasmacytoma (EMP. EMP represents less than 1% of all head and neck malignancies. Case report. We presented a case of EMP of the nasal septum in a 44-year-old male who had progressive difficulty in breathing through the nose and frequent heavy epistaxis on the right side. Nasal endoscopy showed dark red, soft, polypoid tumor in the last third of the right nasal cavity arising from the nasal septum. The biopsy showed that it was plasmacytoma. Bence Jones protein in the urine, serum electrophoresis, bone marrow biopsy, skeletal survey and other screening tests failed to detect multiple myeloma. This confirmed the diagnosis of EMP. The mass was completely removed via an endoscopic approach, and then, 4 week later, radiotherapy was conducted with a radiation dose of 50 Gray. No recurrence was noted in a 3-year follow- up period. Conclusion. EMP of the nasal cavity, being rare and having long natural history, represents a diagnostic and therapeutic challenge for any ear, nose and throat surgeon. Depending on the resectability of the lesion, a combined therapy is the accepted treatment.

  1. [Nasal septal abscess].

    Science.gov (United States)

    Barril, María F; Ferolla, Fausto M; José, Pablo; Echave, Cecilia; Tomezzoli, Silvana; Fiorini, Sandra; López, Eduardo Luis

    2008-12-01

    A nasal septal abscess (NA) is defined as a collection of pus between the cartilage or bony septum and its normally applied mucoperichondrium or mucoperiostium. It is an uncommon disease which should be suspected in a patient with acute onset of nasal obstruction and recent history of nasal trauma, periodontal infection or an inflammatory process of the rhinosinusal region. We report a case of an 8-year-old boy with bilateral NA caused by community-acquired methicillin-resistant Staphylococcus aureus(MR-CO) in order to emphasize the importance of prompt diagnosis and adequate treatment to prevent the potentially dangerous spread of infection and the development of severe functional and cosmetic sequelae.

  2. Cosmetic and Functional Nasal Deformities

    Science.gov (United States)

    ... nasal complaints. Nasal deformity can be categorized as “cosmetic” or “functional.” Cosmetic deformity of the nose results in a less ... taste , nose bleeds and/or recurrent sinusitis . A cosmetic or functional nasal deformity may occur secondary to ...

  3. Nasal obstruction and human communication.

    Science.gov (United States)

    Malinoff, R; Moreno, C

    1989-04-01

    Nasal obstruction may cause a variety of communication disorders, particularly in children. The effects of nasal obstruction on hearing, speech, language, and voice are examined. Methods for assessing the effects of nasal obstruction are delineated, and recommendations for therapeutic interventions are described.

  4. MR implant labelling and its use in clinical MRI practice; MR-Implantatkennzeichnungen und ihre Anwendung in der klinischen MRT-Praxis

    Energy Technology Data Exchange (ETDEWEB)

    Muehlenweg, M. [Krankenhaus Martha-Maria Halle-Doelau, Institut fuer Radiologie, Halle (Saale) (Germany); Schaefers, G. [MR:comp GmbH, Gelsenkirchen (Germany)

    2015-08-15

    Messungen von Patienten mit Implantaten. In juengerer Vergangenheit ist jedoch ein Weg geschaffen worden, diese Kontraindikation legal zu umgehen. Hierfuer sind spezielle Voraussetzungen noetig: Eindeutige Implantatidentifikation und Vorlage der originalen Herstellerkennzeichnung, Gewaehrleistung der geforderten Bedingungen bei ''bedingt MR-sicheren'' Implantaten und Restrisiko-Nutzen-Analyse mit entsprechender Aufklaerung. Dieser Prozess ist u. U. sehr aufwendig, da die Implantate haeufig schlecht dokumentiert und die Detailinformationen der Implantatkennzeichnung ebenfalls nicht selten veraltet oder nicht einfach zu interpretieren sind. Diese Arbeit informiert ueber rechtliche und normative Grundlagen der Messung von Patienten mit Implantaten. Es werden kurz moegliche physikalische Wechselwirkungen mit Implantaten angerissen, moegliche Strategien zur besseren Identifikation und Recherche von Implantaten und ihrer MR-Kennzeichnung aufgezeigt und allgemeine Ansaetze zur Risikominimierung an Beispielen diskutiert. Der zweite Teil geht auf die Inhalte von MR-Implantatkennzeichnungen ein und zeigt die aktuellen Pruefstandards auf. Es werden die fuer die Interpretation von MR-Implantatkennzeichnungen notwendigen Zusatzinformationen aus den Betriebsanleitungen der MR-Scanner erlaeutert. Abschliessend folgen die Erklaerung der aktuellen Muster-MR-Kennzeichnung von Implantaten der FDA (US Food and Drug Administration) und eine exemplarische Anwendung. (orig.)

  5. Anwendung der isothermalen Mikrokalorimetrie zur physikochemischen Charakterisierung molekularer Interaktionen in pharmazeutischen Formulierungen

    OpenAIRE

    Schicke, Burkhard Christoph

    2010-01-01

    Die isothermalen Mikrokalorimetrie (IMC) ermöglicht die Erfassung von Wärmeflüssen im Mikrowattbereich. Der Nutzen und die Aussagekraft dieser Methode wurden bei folgenden physikochemischen Prozessen untersucht: Hydratation von Diclofenac-Natrium (DfNa) zum Tetrahydrat bei verschiedenen Temperaturen und relativen Feuchten, Kompatibilitäts¬untersuchungen von DfNa und amphiphiler Stärke bei 100% rH und Temperaturen bis zu 313 K, Kristallisationsverhalten von unterschiedlichen Triglycerid-Phosph...

  6. Nasalance norms in Greek adults.

    Science.gov (United States)

    Okalidou, Areti; Karathanasi, Asimina; Grigoraki, Eleni

    2011-08-01

    The purposes of this study were to derive nasalance norms for monolingual Greek speakers, to examine nasalance scores as a function of gender and to draw cross-linguistic comparisons based on normative data. Participants read aloud a corpus of linguistic material, consisting of (1) a nasal text, an oral text and a balanced text; (2) a set of nasal sentences and four sets of oral sentences and (3) repetitions of each of 12 syllable types (8 oral and 4 nasal). The last two sets of material corpus were based on an adaptation of the Simplified Nasometric Assessment Procedures Test (SNAP test) test ( MacKay and Kummer, 1994 ) in Greek, called the G-SNAP test. Eighty monolingual healthy young adult speakers of Greek, 40 males (mean age = 21 years) and 40 females (mean age = 20.5 years), with normal hearing and speech characteristics and unremarkable history were included in the study. The Nasometer (model 6200-3) was used to derive nasalance scores. Mean normative nasalance for spoken Greek was 25.50%, based on the G-oronasal text (with 8.6% nasals). Nasalance scores did not differ significantly with respect to gender. Finally, spoken Greek consistently yielded lower nasalance scores than other languages examined in past work. The aforementioned normative data on nasalance of young adult speakers of Greek are valid across gender and have direct clinical utility as they provide valuable reference information for the diagnosis and management of Greek adults with resonance disorders caused by velar dysfunction.

  7. Surgical management of nasal obstruction.

    Science.gov (United States)

    Moche, Jason A; Palmer, Orville

    2012-05-01

    The proper evaluation of the patient with nasal obstruction relies on a comprehensive history and physical examination. Once the site of obstruction is accurately identified, the patient may benefit from a trial of medical management. At times however, the definitive treatment of nasal obstruction relies on surgical management. Recognizing the nasal septum, nasal valve, and turbinates as possible sites of obstruction and addressing them accordingly can dramatically improve a patient's nasal breathing. Conservative resection of septal cartilage, submucous reduction of the inferior turbinate, and structural grafting of the nasal valve when appropriate will provide the optimal improvement in nasal airflow and allow for the most stable results. Copyright © 2012. Published by Elsevier Inc.

  8. Nasal packing with ventilated nasal packs; a comparison with traditional vaseline nasal pack

    International Nuclear Information System (INIS)

    Alam, J.; Siddiqui, M.W.; Abbas, A.; Sami, M.; Ayub, Z.

    2017-01-01

    To compare the benefits of ventilated nasal packing with traditional vaseline guaze nasal packing. Study Design: Randomized controlled trial. Place and Duration of Study: This study was conducted at CMH Multan, from Jun 2014 to Dec 2014. Material and Methods: In this study, sample size of 80 patients was calculated using WHO calculator. Patients were divided in two groups using lottery method endotracheal tube and piece of surgical glove filled with ribbon guaze was utilized for fabricated ventilated nasal pack and compared with traditional nasal packs. Nasal obstruction and sleep disturbance were studied at eight hours and twenty-four hours following surgery using visual analog scale. Results: Mean nasal obstruction with ventilated nasal pack was 45.62 +- 6.17 and with Vaseline nasal pack was 77.67 +- 4.85 which was statistically significant (p=0.001) in both the groups. Mean sleep disturbance in both the groups was 46.32 +- 5.23 and 68.75 +- 2.70 respectively which was statistically significant (p=0.001) in both the groups. Conclusion: Patients with ventilated nasal packs were found to have better tolerance to nasal packs due to less nasal obstruction and sleep disturbance

  9. New manufacturing technologies of two phase tungsten carbide; Neue Technologie zur Herstellung von Wolframschmelzkarbid

    Energy Technology Data Exchange (ETDEWEB)

    Linke, P.; Weiss, K.- H.; Nutsch, G. [Technische Universitaet Ilmenau, Institut fuer Werkstofftechnik, Gustav-Kirchhoff-Strasse 1, Ilmenau (Germany)

    2003-07-01

    A promising application of the inductively coupled RF Plasma technology is the one-step spheroidization and solidification of porous, agglomerated particles. The agglomerated particles are produced by spray drying in a solution of binder and agent. The feedstock consists of WC/W{sub 2}C with a dispersity of 90-120 {mu}m and a carbon concentration of 4.8 mass%. It is the aim of the project to obtain dense spheroidized particles with definite carbon contenent in the region of 3.8-4.3 mass%. (Abstract Copyright [2003], Wiley Periodicals, Inc.) [German] Eine vielversprechende Anwendung der ICP Technologie ist die Sphaeroidisierung und Verfestigung von poroesen, agglomerierten Partikeln. Die agglomerierten Partikel werden durch ein Spruehtrocknungsprozess hergestellt. Das Ausgangsmaterial besteht aus WC/W{sub 2}C mit einer Korngroesse von 90-120 {mu}m und einer Kohlenstoffkonzentration von 4,8 Gew. %. Das Ziel des Projektes war, dichte und sphaeroidisierte Partikel, mit einer definierten Kohlenstoffkonzentration, im Bereich von 3,8-4,3 Gew.%, herzustellen. (Abstract Copyright [2003], Wiley Periodicals, Inc.)

  10. Gas generation from biomass for decentralized power supply systems; Gaserzeugung fuer dezentrale Energiesysteme auf der Basis von Biomasse

    Energy Technology Data Exchange (ETDEWEB)

    Kubiak, H.; Papamichalis, A.; Heek, K.H. van [DMT-Inst. fuer Kokserzeugung und Brennstofftechnik, Essen (Germany)

    1996-12-31

    By a reaction with steam, bioresidues and plants can be converted into a gas consisting mainly of hydrogen, carbon monoxide and methane which can be used for electric power generation in gas engines, gas turbins and fuel cells. The conversion processes, especially the fuel cell process, are environment-friendly and efficient. For decentralized applications (i.e. for biomass volumes of 0.5 to 1 t/h), an allothermal process is recommended which is described in detail. (orig) [Deutsch] Durch Reaktion mit Wasserdampf lassen sich Bioreststoffe und Energiepflanzen zu einem Gas umsetzen, das im wesentlichen aus Wasserstoff, Kohlenmonoxid und Methan besteht und z.B. ueber Gasmotoren, Gasturbinen, vorzugsweise aber Brennstoffzellen zu Strom umgewandelt werden kann. Die Umwandlungsverfahren, insbesondere unter Benutzung von Brennstoffzellen, sind umweltfreundlich und haben einen hohen Wirkungsgrad. Als Vergasungsverfahren eignet sich fuer die dezentrale Anwendung. - d.h. fuer eine Biomassemenge von 0,5 bis 1 t/h - insbesondere das hier beschriebene allotherme Verfahren. (orig)

  11. Gas generation from biomass for decentralized power supply systems; Gaserzeugung fuer dezentrale Energiesysteme auf der Basis von Biomasse

    Energy Technology Data Exchange (ETDEWEB)

    Kubiak, H; Papamichalis, A; Heek, K.H. van [DMT-Inst. fuer Kokserzeugung und Brennstofftechnik, Essen (Germany)

    1997-12-31

    By a reaction with steam, bioresidues and plants can be converted into a gas consisting mainly of hydrogen, carbon monoxide and methane which can be used for electric power generation in gas engines, gas turbins and fuel cells. The conversion processes, especially the fuel cell process, are environment-friendly and efficient. For decentralized applications (i.e. for biomass volumes of 0.5 to 1 t/h), an allothermal process is recommended which is described in detail. (orig) [Deutsch] Durch Reaktion mit Wasserdampf lassen sich Bioreststoffe und Energiepflanzen zu einem Gas umsetzen, das im wesentlichen aus Wasserstoff, Kohlenmonoxid und Methan besteht und z.B. ueber Gasmotoren, Gasturbinen, vorzugsweise aber Brennstoffzellen zu Strom umgewandelt werden kann. Die Umwandlungsverfahren, insbesondere unter Benutzung von Brennstoffzellen, sind umweltfreundlich und haben einen hohen Wirkungsgrad. Als Vergasungsverfahren eignet sich fuer die dezentrale Anwendung. - d.h. fuer eine Biomassemenge von 0,5 bis 1 t/h - insbesondere das hier beschriebene allotherme Verfahren. (orig)

  12. Function and application of ammonia-water adsorption refrigeration cycles; Funktion und Anwendung von Ammoniak-Wasser-Absorptionskaeltemaschinen

    Energy Technology Data Exchange (ETDEWEB)

    Heyse, Christoph; Stuerzebecher, Wolfgang [Tranter Solarice GmbH, Artern (Germany); Cibis, Dominik [Europaeische Studienakademie Kaelte-Klima-Lueftung, Maintal (Germany)

    2012-07-01

    The pursuit of the nations for more energy efficiency and environmentally friendly handling of nature and its resources is growing steadily. This new dimension of environmental awareness led to the fact that Germany has set the goal to become one of the most energy efficient and environmentally friendly economies of the world. Inter alia research and development in the areas of energy efficiency and renewable energy benefit from this. The meanwhile strongly forgotten potential of absorption chillers used for more than 150 years was due to rising energy costs and the rethinking in dealing with existing energy sources, newly discovered. The application of absorption chillers can be found everywhere, where a lot of heat is released unused into the environment. The implementation of the absorption refrigeration technology in power systems can have enormous energetic and thus ecological and economical benefits. Currently, mainly gas-fired cogeneration units whose main purpose is the generation of electricity can be used as heat sources. Particularly versatile is the application of NH{sub 3}-H{sub 2}O absorbers where heating temperatures are located at 100 Celsius and cooling temperatures up to -10 Celsius are needed, for example for air conditioning of buildings, cooling of food-stuff or for process cooling. The contribution under consideration reports on an overview of the working principle of ammonia water absorption chillers and presents various applications and uses in line with a combined power-heat-coldness coupling.

  13. Application and processing of paints hardened by electron beams. Anwendung und Verarbeitung von EB-haertenden Lacken

    Energy Technology Data Exchange (ETDEWEB)

    1984-01-01

    Electron beam hardening is a process for changing liquid surface coatings of different thicknesses by irradiation with electrons of high energy into solid, hard, elastic films. In contrast to the UV process, one can harden pigmented paints with electron beams. An electron accelerator, which remits free electrons is used as the energy source for starting the chemical reaction in the coating material. In order to irradiate flat parts, which were coated with liquid paint by rolling, pouring or spraying, equally with electrons, one must produce an electron curtain, similar to that in a paint pouring machine.

  14. Mord, Selbstmord und Anomie : ein neuer Ansatz zur Operationalisierung und empirischen Anwendung des Anomiekonstruktes von Emile Durkheim

    OpenAIRE

    Mehlkop, Guido; Graeff, Peter

    2006-01-01

    Die Studie stützt sich auf Durkheims Anomietheorie, in der Mord- und Selbstmordraten als soziale Phänomene begriffen werden, die wiederum nur mit anderen sozialen Tatsachen zu erklären sind. Unter dieser soziologischen Perspektive interessiert also nicht das letztliche Motiv des Selbstmörders bzw. Mörders, sondern der Einfluss gesellschaftlicher Verhältnisse. Im Fokus dieser Analyse stehen variierende Mord- und Selbstmordraten zwischen Gesellschaften und über die Zeit hinweg. Verzichtet wird ...

  15. Legal aspects of the production and application of radiopharmaceuticals in Germany; Arzeinmittelrechtliche Aspekte der Herstellung und Anwendung von Radiopharmaka

    Energy Technology Data Exchange (ETDEWEB)

    Kuwert, T.; Prante, O. [Universitaetsklinikum, Erlangen (Germany). Nuklearmedizinische Klinik; Meyer, G. [Medizinische Hochschule Hannover (Germany). Klinik fuer Nuklearmedizin

    2009-06-15

    This article deals with the regulation of the production and use of radiopharmaceuticals in Germany. As in other countries, radiopharmaceuticals may be used when licensed by the German equivalent of the Federal Drug Agency or in clinical trials. Furthermore, non-licensed radiopharmaceuticals can be administered to patients for diagnosis when they are produced in the same institution and not more than 20 doses per week and radiopharmaceutical are given. A prerequisite for these three ways of use is the production of the radiopharmaceutical in question according to the guidelines of the good manufacturing practice (GMP) which creates considerable problems for the usually small PET centers installed in the German university hospitals. German law offers a further possibility to apply non-licensed radiopharmaceuticals for clinical purposes: their administration to patients is not forbidden when performed by a physician who produces the substance himself or is at least responsible for its synthesis. This regulation has, however, been met with criticism by government agencies. (orig.)

  16. Findings relating to the use of ACPI in Windows servers; Erfahrungen in der Anwendung von ACPI bei Windows-Servern

    Energy Technology Data Exchange (ETDEWEB)

    Huser, A.; Grieder, T.

    2004-07-01

    In a practical test, the possibilities and limits of the use of energy-saving sleep modes were compiled for servers of the lower price segment. Many of these servers are used by small to medium-sized enterprises and are left running around the clock, although they are not used at night or during the week-end. The implementation of the sleep modes is based on the so-called ACPI specification (Advanced Configuration and Power Interface), which was created by an industrial consortium. The most advanced of these is the implementation for the Windows Server 2003 operating system. With Linux, the sleep modes are not yet fully available. The test was therefore carried out with the Windows Server 2003 operating system. In many applications, and in particular when the servers are used as file or web servers, no operational disadvantages result from the use of the rest states. By making use of the lowest possible sleep mode during the night and at week-ends, the energy consumption of the server can be halved. For users, the results have been summarised in a two-page fact sheet, which is enclosed with this report as an appendix. (author)

  17. Nasal deposition of ciclesonide nasal aerosol and mometasone aqueous nasal spray in allergic rhinitis patients.

    Science.gov (United States)

    Emanuel, Ivor A; Blaiss, Michael S; Meltzer, Eli O; Evans, Philip; Connor, Alyson

    2014-01-01

    Sensory attributes of intranasal corticosteroids, such as rundown to the back of the throat, may influence patient treatment preferences. This study compares the nasal deposition and nasal retention of a radiolabeled solution of ciclesonide nasal aerosol (CIC-hydrofluoroalkane [HFA]) with a radiolabeled suspension of mometasone furoate monohydrate aqueous nasal spray (MFNS) in subjects with either perennial allergic rhinitis (AR) or seasonal AR. In this open-label, single-dose, randomized, crossover scintigraphy study, 14 subjects with symptomatic AR received a single dose of radiolabeled 74-μg CIC-HFA (37 μg/spray, 1 spray/each nostril) via a nasal metered-dose inhaler or a single dose of radiolabeled 200-μg MFNS (50 μg/spray, 2 sprays/each nostril), with a minimum 5-day washout period between treatments. Initial deposition (2 minutes postdose) of radiolabeled CIC-HFA and MFNS in the nasal cavity, nasopharynx, and on nasal wipes, and retention of radioactivity in the nasal cavity and nasal run-out on nasal wipes at 2, 4, 6, 8, and 10 minutes postdose were quantified with scintigraphy. At 2 and 10 minutes postdose, deposition of radiolabeled CIC-HFA was significantly higher in the nasal cavity versus radiolabeled MFNS (99.42% versus 86.50% at 2 minutes, p = 0.0046; and 81.10% versus 54.31% at 10 minutes, p Deposition of radioactivity on nasal wipes was significantly higher with MFNS versus CIC-HFA at all five time points, and posterior losses of radiolabeled formulation were significantly higher with MFNS at 6, 8, and 10 minutes postdose. In this scintigraphic study, significantly higher nasal deposition and retention of radiolabeled aerosol CIC-HFA were observed versus radiolabeled aqueous MFNS in subjects with AR.

  18. Application of radioactive substances in research in nuclear medicine: current trends and radiation exposure to the study subjects; Anwendung radioaktiver Stoffe in der nuklearmedizinischen Forschung: aktuelle Trends und Strahlenexposition der Probanden

    Energy Technology Data Exchange (ETDEWEB)

    Minkov, V.; Schwarz, E.R.; Bauer, B.; Nosske, D.; Erzberger, A.; Brix, G. [Bundesamt fuer Strahlenschutz, Inst. fuer Strahlenhygiene, Abt. fuer Medizinische Strahlenhygiene, Neuherberg (Germany)

    2001-08-01

    the studies showed, for the period of evaluation, an overall trend towards reduction. (orig.) [German] Ziel: Im Rahmen dieser Studie wurde die Anwendung radioaktiver Stoffe am Menschen in der nuklearmedizinischen Forschung und die damit fuer die Probanden verbundene Strahlenexposition analysiert. Methodik: Hierzu wurden die zwischen 1997 und 1999 vom Bundesamt fuer Strahlenschutz zusammen mit dem Bundesinstitut fuer Arzneimittel und Medizinprodukte begutachteten Antraege nach paragraph 41 Strahlenschutzverordnung ausgewertet. Ergebnisse: Der Schwerpunkt der begutachteten Studien zur diagnostischen Anwendung radioaktiver Stoffe hat sich seit 1998 von onkologischen auf neurologisch/psychiatrische Fragestellungen verlagert, wobei die Anzahl der PET-Studien stetig zunahm. Der Anteil der in diagnostische Studien einbezogenen gesunden Probanden ist von 7 auf 22% angestiegen. Therapeutische Anwendungen radioaktiver Stoffe nahmen seit 1997 um das Dreifache zu, wobei der Schwerpunkt im Bereich der Radioimmuntherapie und der endovaskulaeren Brachytherapie lag. Fuer bis zu 49% der untersuchten gesunden Probanden war die effektive Dosis hoeher als 5 mSv, fuer bis zu 6% dieser Probanden lag sie ueber 20 mSv. Bis zu 22% der Patienten erhielten im Rahmen diagnostischer Studien eine effektive Dosis von 20-50 mSv. Eine Ueberschreitung der 50-mSv-Grenze trat bei bis zu 3% der Patienten auf. Schlussfolgerungen: Trotz zunehmender Anwendung der PET behaelt die konventionelle Nuklearmedizin ihre Bedeutung in der medizinischen Forschung. Weiterentwicklungen auf dem Gebiet der Radiochemie und Molekularbiologie fuehrten zu einer zunehmenden Bedeutung der Radioimmuntherapie. Die Evaluierung neuer Radiopharmaka und die Erweiterung der biomedizinischen Grundlagenforschung resultierte in einem Anstieg des Anteils der in die Studien einbezogenen gesunden Probanden. Die studienbedingte Strahlenexposition der Probanden zeigte fuer den ausgewerteten Zeitraum insgesamt einen ruecklaeufigen Trend

  19. Gebrauch von Komplementärmedizin bei Patienten mit metastasierendem Melanom unter Therapie mit Ipilimumab innerhalb einer klinischen Studie.

    Science.gov (United States)

    Huebner, Jutta; Mohr, Peter; Simon, Jan-Christoph; Fluck, Michael; Berking, Carola; Zimmer, Lisa; Loquai, Carmen

    2016-05-01

    In Deutschland wenden 40-90 % aller Krebspatienten Methoden der komplementären and alternativen Medizin (KAM) an. Bis dato gibt es kein Datenmaterial zum Einsatz der KAM bei Melanompatienten. Das Ziel unserer Studie war es, Daten über den Gebrauch, die Informationsquellen und Ziele von Patienten mit metastasierendem Melanom zu erfassen. Einhundertsechsundfünfzig Patienten aus 25 Studienzentren nahmen an der DecOG-MM-PAL Multibasket Studie teil. Die beteiligten Personen wurden auch gebeten, an einer Nebenstudie teilzunehmen, die ihren Gebrauch von KAM erfassen sollte. Dazu wurde während der Behandlung ein standardisierter Fragebogen zu genau festgelegten Zeitpunkten ausgeteilt. Insgesamt gingen 55 Fragebögen von 32 (21 %) Melanompatienten ein. Von diesen gaben 17 (53 %) ein Interesse an KAM an, und sieben (22 %) machten von KAM Gebrauch. Die Hauptinformationsquellen (31 %) waren Familienmitglieder und Freunde, gefolgt von Ärzten (19 %). Die Hauptgründe für die Anwendung von KAM waren die Stärkung des Immunsystems (41 %) und des Körpers (34 %). Nahrungsergänzungsmittel (Vitamine und Spurenelemente) wurden am häufigsten angewendet (28 %). Eine relativ hohe Anzahl an Patienten mit metastasierendem Melanom machte trotz Teilnahme an einer klinischen Studie von KAM Gebrauch. Wechselwirkungen könnten durch biologisch basierte KAM auftreten, und hier besonders bei immunmodulierenden KAM- Strategien. Um Risiken zu vermeiden, sollte die Kommunikation zwischen den Ärzten und den Patienten verbessert werden. © 2016 Deutsche Dermatologische Gesellschaft (DDG). Published by John Wiley & Sons Ltd.

  20. On the relation of nasal cycling with nasal airway dimensions

    Energy Technology Data Exchange (ETDEWEB)

    Guilmette, R A; Wolff, R K

    1988-12-01

    The size and configuration of the nasal airways of humans change with time as a result of the normal process of congestion/decongestion of the erectile tissue of the nasal mucosa. To determine the extent to which airway areas change in vivo, we used magnetic resonance imaging (MRI) to quantitate both the cross-sectional area and perimeter of coronal sections of the entire nasal airway of a human subject. Changes in airway size or patency were indexed to measured changes in unilateral nasal airway resistance determined by posterior rhino manometry. The results of this study in which two MRI scans were performed for presumed left-side patency and two for right-side patency, showed that changes in nasal airway resistance were difficult to ascribe to systematic changes In the sizes of the airways. (author)

  1. On the relation of nasal cycling with nasal airway dimensions

    International Nuclear Information System (INIS)

    Guilmette, R.A.; Wolff, R.K.

    1988-01-01

    The size and configuration of the nasal airways of humans change with time as a result of the normal process of congestion/decongestion of the erectile tissue of the nasal mucosa. To determine the extent to which airway areas change in vivo, we used magnetic resonance imaging (MRI) to quantitate both the cross-sectional area and perimeter of coronal sections of the entire nasal airway of a human subject. Changes in airway size or patency were indexed to measured changes in unilateral nasal airway resistance determined by posterior rhino manometry. The results of this study in which two MRI scans were performed for presumed left-side patency and two for right-side patency, showed that changes in nasal airway resistance were difficult to ascribe to systematic changes In the sizes of the airways. (author)

  2. Mechanical/thermal dehydration - a new process for treatment of peat and coal; Mechanisch/Thermische Entwaesserung - ein neues Verfahren zur Veredelung von Torf und Kohlen

    Energy Technology Data Exchange (ETDEWEB)

    Bergins, C; Berger, S; Strauss, K [Dortmund Univ. (Germany); Elsen, R O [RWE Energie, Essen (Germany); Erken, M [Rheinbraun AG, Koeln (Germany); Bielfeldt, F B [Dieffenbacher, Eppingen (Germany)

    1998-09-01

    In order to keep German brown coal competitive, new technologies for enhanced efficiency of power generation from brown coal were developed in the past few years. At a water content of 50-60 percent by weight, much energy is lost for evaporation. Reduction of the water content will incur a 5 percent effiency enhancement. A new process was developed at Dortmund university, i.e. mechanical/thermal dehydration in which the water contained in brown coal is removed by heat and mechanical pressure. The process is described, and its applicability for other moist fuels, e.g. peat or waste from the paper and wood processing industry ist discussed. (orig./SR) [Deutsch] Damit Braunkohle in Deutschland als heimischer und subventionsfreier Energietraeger diesen Stellenwert behaupten und in Zukunft weiter ausbauen kann, wurde in den letzten Jahren verstaerkt die Entwicklung neuer Technologien zur Effizienzsteigerung der Braunkohleverstromung vorangetrieben. Bei der Verbrennung von Braunkohlen mit Wassergehalten von 50-60 Gew.-% ist in herkoemmlichen Kraftwerken ein erheblicher Teil des Energieinhaltes zur Verdampfung des Wassers mit Hilfe von heissen Rauchgasen in sogenannten Mahltrockungsanlagen erforderlich. Durch eine energetisch guenstige Reduzierung des Wassergehaltes vor der Verbrennung sind hier Wirkungsgradsteigerungen um bis zu 5 Prozentpunkte moeglich. Ein neues, fuer diese Aufgabenstellung einsetzbares Verfahren ist das am Lehrstuhl Energieprozesstechnik und Stroemungsmechanik der Universitaet Dortmund entwickelte Mechanisch/Thermische Entwaesserungsverfahren (MTE-Verfahren). Durch die kombinierte Anwendung von Waerme und mechanischem Druck laesst sich das in der Kohle enthaltene Wasser in fluessiger Form entfernen. Neben der Darstellung des MTE-Verfahrens am Beispiel von Braunkohle soll im folgenden auch auf die Moeglichkeiten der Anwendung des Verfahrens fuer andere feuchte Brennstoffe wie Torf und Abfaelle aus der Papier- und Holzverarbeitung eingegangen werden

  3. Enzootic Nasal Adenocarcinoma: Cytological and ...

    African Journals Online (AJOL)

    Enzootic nasal adenocarcinoma (ENA), a contagious retroviral disease of sheep and goats, characterized by neoplastic growth of the ethmoidal mucosa in the nasal cavity is described in a West African Dwarf goat (WAD). A two-year old WAD goat, weighing approximately 20kg was observed in the Teaching and Research ...

  4. Medienpädagogische Gestaltungsideen zur Integration von E-Learning in der Hochschullehre

    Directory of Open Access Journals (Sweden)

    Ricarda T.D. Reimer

    2003-08-01

    Full Text Available Im ersten Teil des Artikels geht die Autorin der Frage nach, welche Rolle E-Learning an Hochschulen einnimmt. Sie nennt Projekte, die vom Bund (teilweise mit kommerzieller Beteiligung gefördert werden und äußert die These, dass E-Learning didaktischer Konzepte bedarf und somit eine Aufwertung der Pädagogik bedeuten könnte. Im Zuge des Wettbewerbs unter den Hochschulen müssten sich wissenschaftliche MitarbeiterInnen mit der Konzeptualisierung von E- Learning und folglich mit mediendidaktischen Grundlagen auseinander setzen. Im Anschluss an diese, bildungstheoretischen Ausführungen beschreibt sie detailliert ein Seminar "Bildungstheorie in der Weiterbildung", das die Universitäten Bielefeld und Flensburg gemeinsam durchführten. Im Mittelpunkt stand die Anwendung von "blended learning". Präsenzelemente wurden von Online- Phasen abgelöst und begleitet. Das Seminar wurde evaluiert und kann somit Anstöße für weitere Konzepte geben.

  5. Chondrosarcoma of the nasal septum

    International Nuclear Information System (INIS)

    Yamamoto, Seiji; Motoori, Ken; Ueda, Takuya; Osaka, Iwao; Takano, Hideyuki; Nagata, Hiroshi

    2002-01-01

    The nasal septum is a particularly rare site of origin of chondrosarcoma. Cranial base invasion may be at hand, with such lesions making complete tumor removal difficult. MRI techniques allow precise definition of tumor extent. In the described case, CT and Dynamic MR imaging were performed in a case of chondrosarcoma of the nasal septum. Imaging clearly illustrated size and extent of the mass with central regions of internal calcification. Dynamic MRI was additionally performed, which helped to define the presumed origin of the lesion from the nasal septum. (orig.)

  6. Nasal Glial Heterotopia with Cleft Palate.

    Science.gov (United States)

    Chandna, Sudhir; Mehta, Milind A; Kulkarni, Abhishek Kishore

    2018-01-01

    Congenital midline nasal masses are rare anomalies of which nasal glial heterotopia represents an even rarer subset. We report a case of a 25-day-old male child with nasal glial heterotopia along with cleft palate suggesting embryonic fusion anomaly which was treated with excision and primary closure for nasal mass followed by palatal repair at later date.

  7. Nasal glial heterotopia with cleft palate

    Directory of Open Access Journals (Sweden)

    Sudhir Chandna

    2018-01-01

    Full Text Available Congenital midline nasal masses are rare anomalies of which nasal glial heterotopia represents an even rarer subset. We report a case of a 25-day-old male child with nasal glial heterotopia along with cleft palate suggesting embryonic fusion anomaly which was treated with excision and primary closure for nasal mass followed by palatal repair at later date.

  8. Ellis Von Creveld Syndrome

    Directory of Open Access Journals (Sweden)

    Afshar H

    1999-01-01

    Full Text Available One patient with Ellis Von Creveld syndrome contains: dwarfism, congenital heart"ndisease, ectodermal dysplasia, polyductyly, an abnormally wide labial frenum and maxillary"nmolars with single root.

  9. Lars von Triers film

    DEFF Research Database (Denmark)

    Nielsen, Lisbeth Overgaard

    2007-01-01

    Afhandlingen undersøger Lars von Triers filmæstetik, som den kommer til udtryk i spillefilmene fra perioden 1984-2007. Afhandlingen analyserer de enkelte films stil, virkningsstrategi og betydningsdannelse.......Afhandlingen undersøger Lars von Triers filmæstetik, som den kommer til udtryk i spillefilmene fra perioden 1984-2007. Afhandlingen analyserer de enkelte films stil, virkningsstrategi og betydningsdannelse....

  10. Environmental protection by cost minimization: Least Cost Planning for traffic. Includes a guide for the application in local communities; Umweltentlastung durch Kostenminimierung: Least Cost Planning im Verkehr. Mit Leitfaden fuer die Anwendung in Kommunen

    Energy Technology Data Exchange (ETDEWEB)

    Bracher, T.; Diegmann, V.; Eckart, C.F.; Liwicki, M.; Lobenberg, G.; Wetzel, C. [Gesellschaft fuer Informatik, Verkehrs- und Umweltplanung mbH (IVU), Berlin (Germany); Bergmann, M.; Uricher, A.; Lueers, A. [Oeko-Institut, Inst. fuer Angewandte Oekologie e.V., Freiburg im Breisgau (Germany); Becker, U.; Karl, G.; Karl, B.; Voellings, A. [Technische Univ. Dresden (Germany). Lehrstuhl fuer Verkehrsoekologie

    1999-08-01

    den Energiesektor entwickelte Least Cost Planning zu uebertragen. Auf der Basis einer Analyse der in der Literatur dokumentierten Ansaetze und der vorhandenen Bewertungsverfahren fuer oeffentliche Massnahmen wurden Anforderungen an Methodik und Entwicklung eines verbesserten Bewertungsverfahrens formuliert. Dieses muss verkehrsmitteluebergreifend (intermodal) und verkehrsuebergreifend (integriert) sein. Das entwickelte Verfahren ermoeglicht erstens die Darstellung der Verkehrsausgaben und Einnahmen einer Stadt im Jahresueberblick, und zweitens die vergleichende Bewertung von Planungsvarianten. Dies wurde anhand verschiedener Varianten fuer die Erschliessung eines Gewerbegebiets im Norden Freiburgs illustriert. Dabei wurden drei Varianten untersucht: die Verlaengerung einer Stadtbahnstrecke, die Verdichtung des Busverkehrsnetzes und die Einrichtung von Service-Stationen und weitere Foerdermassnahmen fuer den Fahrradverkehr. Neben den Berechnungen von Einnahmen und Ausgaben fuer jede Variante wurde eine uebersichtliche Darstellung von Auswirkungen auf die Verkehrsnachfrage, die Belastung mit Luftschadstoffen und Laerm sowie den Flaechenverbrauch entwickelt. Im Ergebnis schneidet die Erschliessung mit dem Fahrrad tendenziell guenstig ab. Der Abschlussbericht umfasst drei Baende sowie einen Leitfaden zur Anwendung des Verfahrens in Kommunen. Dazu gehoert ein Satz Tabellen im Excel Format, der die leichte Anwendung ermoeglicht. (orig.)

  11. Kompressionstherapie - Versorgungspraxis: Informationsstand von Patienten mit Ulcus cruris venosum.

    Science.gov (United States)

    Protz, Kerstin; Heyer, Kristina; Dissemond, Joachim; Temme, Barbara; Münter, Karl-Christian; Verheyen-Cronau, Ida; Klose, Katharina; Hampel-Kalthoff, Carsten; Augustin, Matthias

    2016-12-01

    Eine Säule der kausalen Therapie bei Patienten mit Ulcus cruris venosum ist die Kompressionstherapie. Sie unterstützt die Abheilung, reduziert Schmerzen und Rezidive und steigert die Lebensqualität. Bislang existieren kaum wissenschaftliche Daten zu dem Versorgungsstand und fachspezifischem Wissen von Patienten mit Ulcus cruris venosum. Standardisierte Fragebögen wurden bundesweit in 55 Pflegediensten, 32 Arztpraxen, vier Wundzentren und -sprechstunden sowie einem Pflegetherapiestützpunkt von Patienten mit Ulcus cruris venosum bei Erstvorstellung anonym ausgefüllt. Insgesamt nahmen 177 Patienten (Durchschnittsalter 69,4 Jahre; 75,1 % Frauen) teil. Ein florides Ulcus cruris venosum bestand im Mittel 17 Monate. 31,1 % hatten keine Kompressionstherapie, 40,1 % Binden und 28,8 % Strümpfe. Bei der Bestrumpfung hatten 13,7 % Kompressionsklasse III, 64,7 % Kompressionsklasse II und 19,6 % Kompressionsklasse I. 70,6 % legten die Strümpfe nach dem Aufstehen an, 21,1 % trugen sie Tag und Nacht. 39,2 % bereiteten die Strümpfe Beschwerden. Lediglich 11,7 % hatten eine An- und Ausziehhilfe. Die Binden wurden im Mittel 40,7 Wochen getragen und bei 69 % nicht unterpolstert. Bei 2,8 % wurde der Knöchel- und Waden-Umfang zur Erfolgskontrolle gemessen. Venensport machten 45,9 %. Ein Drittel hatte keine Kompressionsversorgung, obwohl diese eine Basismaßnahme der Therapie des Ulcus cruris venosum ist. Zudem ist deren korrekte Auswahl und Anwendung angesichts der langen Bestandsdauer der Ulzerationen zu hinterfragen. Weiterführende Fachkenntnisse bei Anwendern und Verordnern sowie Patientenschulungen sind erforderlich. © 2016 Deutsche Dermatologische Gesellschaft (DDG). Published by John Wiley & Sons Ltd.

  12. Image diagnosis of nasal bone fracture

    International Nuclear Information System (INIS)

    Hirota, Yoshiharu; Shimizu, Yayoi; Iinuma, Toshitaka.

    1988-01-01

    Twenty cases of nasal bone fractures were evaluated as to the types of fractures based upon HRCT findings. Conventional X-Ray films for nasal bones were analyzed and compared with HRCT findings. Nasal bone fractures were classified into lateral and frontal fractures. HRCT images were evaluated in three planes including upper, middle and lower portions of the nasal bone. Fractures favored males of teens. Lateral fracture gave rise to the fractures of the nasal bone opposite to the external force, loosening of the ipsilateral nasomaxillary sutures and fractures of the frontal process of the maxilla. Conventional X-Ray films were reevaluated after HRCT evaluation and indications of nasal bone fractures were determined. In addition to the discontinuity of the nasal dorsum, fracture lines parallel to and beneath the nasal dorsum and indistinct fracture lines along the nasomaxillary sutures are the indication of nasal bone fractures by conventional X-Ray films. (author)

  13. Bilateral cleft lip nasal deformity

    Directory of Open Access Journals (Sweden)

    Singh Arun

    2009-01-01

    Full Text Available Bilateral cleft lip nose deformity is a multi-factorial and complex deformity which tends to aggravate with growth of the child, if not attended surgically. The goals of primary bilateral cleft lip nose surgery are, closure of the nasal floor and sill, lengthening of the columella, repositioning of the alar base, achieving nasal tip projection, repositioning of the lower lateral cartilages, and reorienting the nares from horizontal to oblique position. The multiplicity of procedures in the literature for correction of this deformity alludes to the fact that no single procedure is entirely effective. The timing for surgical intervention and its extent varies considerably. Early surgery on cartilage may adversely affect growth and development; at the same time, allowing the cartilage to grow in an abnormal position and contributing to aggravation of deformity. Some surgeons advocate correction of deformity at an early age. However, others like the cartilages to grow and mature before going in for surgery. With peer pressure also becoming an important consideration during the teens, the current trend is towards early intervention. There is no unanimity in the extent of nasal dissection to be done at the time of primary lip repair. While many perform limited nasal dissection for the fear of growth retardation, others opt for full cartilage correction at the time of primary surgery itself. The value of naso-alveolar moulding (NAM too is not universally accepted and has now more opponents than proponents. Also most centres in the developing world have neither the personnel nor the facilities for the same. The secondary cleft nasal deformity is variable and is affected by the extent of the original abnormality, any prior surgeries performed and alteration due to nasal growth. This article reviews the currently popular methods for correction of nasal deformity associated with bilateral cleft lip, it′s management both at the time of cleft lip repair

  14. Nasal Delivery of High Molecular Weight Drugs

    Directory of Open Access Journals (Sweden)

    Erdal Cevher

    2009-09-01

    Full Text Available Nasal drug delivery may be used for either local or systemic effects. Low molecular weight drugs with are rapidly absorbed through nasal mucosa. The main reasons for this are the high permeability, fairly wide absorption area, porous and thin endothelial basement membrane of the nasal epithelium. Despite the many advantages of the nasal route, limitations such as the high molecular weight (HMW of drugs may impede drug absorption through the nasal mucosa. Recent studies have focused particularly on the nasal application of HMW therapeutic agents such as peptide-protein drugs and vaccines intended for systemic effects. Due to their hydrophilic structure, the nasal bioavailability of peptide and protein drugs is normally less than 1%. Besides their weak mucosal membrane permeability and enzymatic degradation in nasal mucosa, these drugs are rapidly cleared from the nasal cavity after administration because of mucociliary clearance. There are many approaches for increasing the residence time of drug formulations in the nasal cavity resulting in enhanced drug absorption. In this review article, nasal route and transport mechanisms across the nasal mucosa will be briefly presented. In the second part, current studies regarding the nasal application of macromolecular drugs and vaccines with nanoand micro-particulate carrier systems will be summarised.

  15. Innovation for improvement of pedestrian protection as the challenge for the development of front-end structures of passenger cars; Innovationen zur Verbesserung des Fussgaengerschutzes als Herausforderung fuer die Entwicklung von PKW-Vorbaustrukturen

    Energy Technology Data Exchange (ETDEWEB)

    Kramer, F.; Weidemann, W.; Jansohn, W.; Schneider, M. [EDAG Engineering and Design AG, Fulda (Germany)

    2001-07-01

    Requirements for improvement of pedestrian protection are the result of real-world accidents and test conditions, which take an important role in development of front-end structures of passenger cars at present, based on legal regulations (EU directives expected in 2005) and on car assessment programmes (application as per EuroNCAP since 1997). Styling and packaging are major considerations in conceptual realisation on a large scale. Furthermore, demands for minimisation of weight and cost have to be considered as marginal conditions. Solutions for this conflict of aims, which results from the new safety requirements and performance criteria for front-end structures, are to be represented and discussed based on concrete examples. (orig.) [German] Anforderungen zur Verbesserung des Fussgaengerschutzes resultieren einerseits aus dem Unfallgeschehen und andererseits aus Versuchsbedingungen, die derzeit auf der Basis von gesetzlichen Regelungen (erwartete EU-Richtlinie etwa im Jahr 2005) und von Sicherheitsbewertungen (Anwendung im Rahmen von EuroNCAP seit 1997) in der Vorbau-Entwicklung von Personenkraftwagen eine bedeutende Rolle einnehmen. Die konzeptionelle Umsetzung tangiert sowohl Styling als auch Packaging in erheblichem Umfang, darueber hinaus sind als Randbedingungen die Forderungen nach der Minimierung von Gewicht und Kosten zu beruecksichtigen. Die Loesungen dieses Zielkonfliktes, deren Wirkungsfeld durch die neuen Sicherheitsanforderungen und die Auslegungskriterien fuer Vorbaustrukturen aufgespannt wird, sollen anhand von konkreten Beispielen dargestellt und diskutiert werden. (orig.)

  16. Cosmetic reconstruction of a nasal plane and rostral nasal skin defect using a modified nasal rotation flap in a dog

    NARCIS (Netherlands)

    ter Haar, G.; Buiks, S.C.; Kirpensteijn, J.

    2013-01-01

    Abstract OBJECTIVE: To report reconstruction of a defect of the nasal plane and the rostral dorsum of the nose in a dog using a nasal rotation flap with Burow's triangles. STUDY DESIGN: Clinical report. ANIMALS: Mixed-breed dog (1.5 years, 8.6 kg). METHODS: A nasal defect caused by chronic

  17. Experimental investigation of nasal airflow.

    Science.gov (United States)

    Doorly, D; Taylor, D J; Franke, P; Schroter, R C

    2008-05-01

    The airway geometry of the nasal cavity is manifestly complex, and the manner in which it controls the airflow to accomplish its various physiological functions is not fully understood. Since the complex morphology and inaccessibility of the nasal passageways precludes detailed in-vivo measurements, either computational simulation or in-vitro experiments are needed to determine how anatomical form and function are related. The fabrication of a replica model of the nasal cavity, of a high optical clarity and derived from in-vivo scan data is described here, together with characteristics of the flow field investigated using particle image velocimetry (PIV) and flow visualization. Flow visualization is shown to be a capable and convenient technique for identifying key phenomena. Specifically the emergence of the jet from the internal nasal valve into the main cavity, how it impacts on the middle turbinate, and the large enhancement of dispersion that accompanies the initial appearance of flow instability are revealed as particularly significant features. The findings from the visualization experiments are complemented by PIV imaging, which provides quantitative detail on the variations in velocity in different regions of the nasal cavity. These results demonstrate the effectiveness of the cavity geometry in partitioning the flow into high shear zones, which facilitate rapid heat transfer and humidification from the nasal mucosa, and slower zones affording greater residence times to facilitate olfactory sensing. The experimental results not only provide a basis for comparison with other computational modelling but also demonstrate an alternative and flexible means to investigate complex flows, relevant to studies in different parts of the respiratory or cardiovascular systems.

  18. UIS Baden-Wuerttemberg. AJA project. Application of JAVA-based solutions in environment, transport and administration. Phase II 2001; UIS Baden-Wuerttemberg. Projekt AJA. Anwendung JAVA-basierter Loesungen in den Bereichen Umwelt, Verkehr und Verwaltung. Phase II 2001

    Energy Technology Data Exchange (ETDEWEB)

    Mayer-Foell, R.; Keitel, A.; Geiger, W. (eds.)

    2001-12-01

    Information and communication technology facilitates data acquisition, recording, evaluation and transmission in many fields of society, but even experts tend to get lost in the flood of data that are available. In order to make it possible to integrate new technological developments in information systems, the Minister of Environment and Transportation continues the project AJA (''Application of JAVA-based solutions'') which was started in 2000. AJA is a sequel to the GLOBUS project which was terminated in 1999. (GLOBUS - Globale Umweltsachdaten im UIS Baden-Wuerttemberg und anderen Systemen). [German] Die Bereiche Umwelt, Verkehr und Verwaltung profitieren bei der Erhebung, Erfassung, Auswertung, Darstellung und Weitergabe ihrer Daten in hohem Masse von Informations- und Kommunikationstechnik (IuK). Manche Darstellungsweisen und Berechnungen werden dadurch erst moeglich. Uebergreifende Zusammenhaenge koennen mit Hilfe der IuK aufgezeigt werden. Die Verwaltung muss Technologien einsetzen, wie sie in der Wirtschaft fuer die Zusammenfuehrung von verteilten Unternehmensdaten verwendet werden, um Entscheidungs grundlagen fuer die Unternehmenspolitik zu liefern (z.B. Data Warehouse). In solchen ''Warenhaeusern von Daten'' finden sich oft nur Experten zurecht. Unsere Herausforderung ist es, diese komplexen Zusammenhaenge nicht nur dem Experten, sondern auch dem Buerger auf moeglichst einfache und wirtschaftliche Weise zu vermitteln. Dem Buerger ist der freie Zugang zu Informationen ueber die Umwelt zu ermoeglichen. Wir sind damit auf dem Wege zu einem Marktplatz von Daten und Informationen fuer den Buerger und die Verwaltung. Um neue technologische Entwicklungen in Informationssystemen einsetzen zu koennen, fuehrt das Ministerium fuer Umwelt und Verkehr (UVM) das 2000 begonnene FuE-Vorhaben AJA ''Anwendung JAVA-basierter Loesungen'' fort. AJA baut auf dem 1999 abgeschlossenen Vorhaben GLOBUS (Globale

  19. Nasal Inserts for Drug Delivery: An Overview

    African Journals Online (AJOL)

    In this review, the benefits, limitations and absorption mechanisms of the nasal route, as well ... molecules including peptide and proteins for ... (Mw) drugs, rapid and fast onset of action due to ... while the former act by disrupting the nasal.

  20. Use of modeling and simulation in the planning, analysis and interpretation of ultrasonic testing; Einsatz von Modellierung und Simulation bei der Planung, Analyse und Interpretation von Ultraschallpruefungen

    Energy Technology Data Exchange (ETDEWEB)

    Algernon, Daniel [SVTI Schweizerischer Verein fuer technische Inspektionen, Wallisellen (Switzerland). ZfP-Labor; Grosse, Christian U. [Technische Univ. Muenchen (Germany). Lehrstuhl fuer Zerstoerungsfreie Pruefung

    2016-05-01

    im Bauteil) an dessen akustischen Grenzflaeche interagieren. Aus dem an der Bauteiloberflaeche empfangenen Signal soll diese Interaktion erkannt und interpretiert werden, um Rueckschluesse auf das Vorhandensein des Zielobjektes zu ziehen sowie gegebenenfalls dessen Ausdehnung und Position (naeherungsweise) zu bestimmen. Obgleich die grundliegenden physikalischen Prinzipien der Anwendung elastischer Wellen in der ZfP bekannt sind, koennen komplexe Verhaeltnisse in Form von beschraenkter Zugaenglichkeit, Bauteilgeometrien oder Art und Form von Reflektoren die Durchfuehrung und Auswertung kompliziert werden lassen. So ist bereits die Abschaetzung der Erfolgsaussichten einer Pruefung oftmals nicht trivial. Diese Umstaende verdeutlichen die Bedeutung des Einsatzes von Simulationsrechnungen, die eine theoretisch fundierte Basis fuer die Pruefung ermoeglichen und mit denen sich Pruefsysteme optimieren lassen. Die dabei einsetzbaren Simulationsverfahren sind vielfaeltig. Gebraeuchlich sind insbesondere die Finite-Elemente-Methode, die Elasto Finite Integration Technique sowie semi-analytische Berechnungsverfahren.

  1. Haemangiopericytoma of the nasal cavity

    Energy Technology Data Exchange (ETDEWEB)

    Weber, W.; Henkes, H.; Berg-Dammer, E.; Kuehne, D. [Alfred Krupp Krankenhaus, Essen (Germany). Klinik fuer Radiologie und Neuroradiologie; Metz, K.A. [Inst. fuer Pathologie, Universitaetsklinikum der Universitaets-Gesamthochschule Essen (Germany)

    2001-02-01

    Haemangiopericytomas (HPC) are rare vascular tumours originating from a pericytes, a term coined by Zimmermann to refer to the main location of this cell line in the pericapillary connective tissue. HPC may arise in any part of the body. We report a 29-year-old man with a histologically proven nasal haemangiopericytoma-like tumour. The lesion was embolised through the ophthalmic artery before it was removed surgically. The main symptoms of nasal HPC are epistaxis and obstruction of the nose. Malignant and benign clinical courses have been described. Local recurrence and metastases may be observed years after initial diagnosis. (orig.)

  2. ANTHROPOMETRIC STUDY OF NASAL INDEX OF EGYPTIANS

    OpenAIRE

    Abdelmonem Awad Hegazy

    2014-01-01

    Background: The nasal index determination is one of the most commonly used anthropometric parameters in classifying human races. There are few reports in medical literature concerning nasal index that specifically address particular Egyptian populations. The objective of this study was to determine the normal parameters of external nose (width, height and nasal index) in Egyptians. Methods: The study was conducted randomly on healthy Egyptian subjects of both sexes. Nasal height and width ...

  3. Does Post Septoplasty Nasal Packing Reduce Complications?

    Directory of Open Access Journals (Sweden)

    Bijan Naghibzadeh

    2011-01-01

    Full Text Available The main issues in nasal surgery are to stabilize the nose in the good position after surgery and preserve the cartilages and bones in the favorable situation and reduce the risk of deviation recurrence. Also it is necessary to avoid the synechia formation, nasal valve narrowing, hematoma and bleeding. Due to the above mentioned problems and in order to solve and minimize them nasal packing, nasal splint and nasal mold have been advised. Patients for whom the nasal packing used may faced to some problems like naso-pulmonary reflex, intractable pain, sleep disorder, post operation infection and very dangerous complication like toxic shock syndrome. We have two groups of patients and three surgeons (one of the surgeons used post operative nasal packing in his patients and the two others surgeons did not.Complications and morbidities were compared in these two groups. Comparing the two groups showed that the rate of complication and morbidities between these two groups were same and the differences were not valuable, except the pain and discomfort post operatively and at the time of its removal. Nasal packing has several risks for the patients while its effects are not studied. Septoplasty can be safely performed without postoperative nasal packing. Nasal packing had no main findings that compensated its usage. Septal suture is one of the procedures that can be used as alternative method to nasal packing. Therefore the nasal packing after septoplasty should be reserved for the patients with increased risk of bleeding.

  4. Rhizostomeen von Manila

    NARCIS (Netherlands)

    Stiasny, G.

    1924-01-01

    Die hier beschriebene kleine Scyphomedusen-Sammlung wurde von Herrn Director P. B. Sivickis, Dept. of Zoology, University of Philippines, Manila, dem Rijksmuseum van Natuurlijke Historie in Leiden überwiesen. Das Material wurde im December 1922 in Manila-bay gefischt und befindet sich in bestem

  5. Schmetterlinge von Madeira

    NARCIS (Netherlands)

    Martin, K.

    1941-01-01

    Wer auf einer ozeanischen Insel Schmetterlinge sammeln will, darf seine Erwartungen nicht zu hoch spannen; aber dennoch waren meine Frau und ich sehr enttäuscht, als uns auf einer Reise nach Madeira von einer dort angesessenen, gebildeten Dame gesagt wurde, sie habe auf der Insel niemals einen

  6. Biologischer Anbau von Strauchbeeren

    OpenAIRE

    Schmid, Andi

    2004-01-01

    Das Merkblatt enthält auf Österreich angepasste, praxisnahe Informationen zur Produktion von hochwertigen Strauchbeeren wie Himbeeren, Brombeeren, Johannisbeeren, Stachelbeeren und Heidelbeeren. Weiterhin: übersichtliche Hinweise zur Planung, Standortwahl, Sortenauswahl, Bodenvorbereitung und Pflanzung, Bewässerung, Nährstoffversorgung, Witterungsschutz, Beikrautregulierung, Ernte und Lagerung. (Diese Publikation enthält spezifische Informationen für Österreich)

  7. Immunophenotype Heterogeneity in Nasal Glomangiopericytoma

    Directory of Open Access Journals (Sweden)

    Adriana Handra-Luca

    2015-01-01

    Full Text Available Nasal glomangiopericytoma is rare. The immunophenotype is heterogeneous, more frequently smooth-muscle-actin and CD34-positive. We report expression patterns for several vascular-related proteins such as CD99, CD146, Bcl2, and WT1 as well as for treatment-related proteins such as mTOR and EGFR in a nasal glomangiopericytoma. The patient (woman, 86 years presented with a left nasal tumefaction. The resected specimen (1.5-cm showed a glomangiopericytoma. Tumor cells expressed smooth-muscle-actin, CD31, CD34, and progesterone receptor. They also expressed the vascular-cell-related proteins Bcl2, CD99, CD146, and WT1, as well as mTOR and EGFR. Nasal glomangiopericytomas show immunohistochemical heterogeneity for vascular-related markers, suggesting a possible extensive pericytic differentiation. The expression of potential targets for drug treatments such as mTOR and EGFR may impact on the clinical follow-up of these tumors occurring at advanced ages, which may require complex surgery.

  8. Relation between epistaxis, external nasal deformity, and septal deviation following nasal trauma

    Science.gov (United States)

    Daniel, M; Raghavan, U

    2005-01-01

    Objectives: To find if the presence of epistaxis after nasal trauma can be used to predict post-traumatic external nasal deformity or a symptomatic deviated nasal septum. Methods: Retrospective analysis of all patients seen in the fractured nose clinic by the first author between 17 October 2003 and 27 February 2004. Presence of epistaxis, newly developed external nasal deformity, and the presence of a deviated nasal septum with new symptoms of nasal obstruction were noted. Results: A total of 139 patients were included in the study. Epistaxis following injury was noted in 106 (76%). Newly developed external nasal deformity was noted in 71 (51%), and 33 (24%) had a deviated nasal septum with new symptoms of nasal obstruction. Of the 106 patients with post-trauma epistaxis, 50 (67%) had newly developed external nasal deformity and of the 33 patients without post-traumatic epistaxis, 11 (33%) had nasal deformity (pepistaxis was not associated with the presence of a newly symptomatic deviated septum (25% in patients with epistaxis after injury versus 18% if there was no epistaxis). Conclusions: Presence of epistaxis after nasal trauma is associated with a statistically significant increase in external nasal deformity. However, one third of patients without epistaxis following nasal trauma also had external nasal deformity and hence all patients with a swollen nose after injury, irrespective of post-trauma epistaxis, still need to be referred to the fractured nose clinic. PMID:16244333

  9. Interactions between industrial organic pollutants and rhizosphere components and documentation of material streams in plant-based wastewater treatment plants - laboratory experiments; Wechselwirkungen industrieller organischer Schadstoffe mit Rhizosphaerenkomponenten und Bilanzierung von Stoffstroemen in Pflanzenklaeranlagen - Laborversuche

    Energy Technology Data Exchange (ETDEWEB)

    Plugge, J.

    2001-07-01

    The purpose of the present study was to examine the suitability of plant/soil systems for cleaning organically polluted effluents and to assess the influence of plant growth and dissolved humic substances on processes leading to the elimination of organic pollutants. This involved an examination of sorption interactions between selected pollutants on the one hand and sand and root material on the other, use of vertically irrigated plant-bearing sand columns for simulating real plant-based wastewater treatment plants, assessment of the cleaning efficiency of these systems with respect to the employed model pollutants and determination of the contamination of the filter material and plants with pollutants. Radiotracer techniques were used to determine pollution paths of phenanthrene and its microbial degradation in the model system. [German] In der vorliegenden Arbeit wurde die Eignung von Pflanze/Boden-Systemen zur Reinigung carbochemisch belasteter Abwaesser untersucht und der Einfluss eines Pflanzenbewuchses sowie geloester Huminstoffe auf die Prozesse, die zur Entfernung organischer Schadstoffe fuehren, bewertet. Die Bearbeitung dieses Themas umfasste Untersuchungen zu Sorptionswechselwirkungen ausgewaehlter Schadstoffe mit Sand- und Wurzelmaterial, die Anwendung vertikal durchstroemter, bepflanzter Sandsaeulen zur Nachbildung realer Pflanzenklaeranlagen, die Erfassung der Reinigungseffizienz dieser Systeme fuer die Modellschadstoffe sowie die Bestimmung der Schadstoffkontamination des Filtermaterials und der Pflanzen. Unter Anwendung der Radiotracertechnik erfolgte darueber hinaus die Bestimmung der Schadstoffpfade von Phenanthren einschliesslich des mikrobiellen Abbaus im Modellsystem. (orig.)

  10. Use of wastes in high-temperature processes of the chemical industry; Verwertung von Abfaellen in Hochtemperaturprozessen der chemischen Industrie

    Energy Technology Data Exchange (ETDEWEB)

    Seifert, H. [Forschungszentrum Karlsruhe GmbH Technik und Umwelt (Germany); Domschke, T.; Steinebrunner, K. [BASF AG, Ludwigshafen am Rhein (Germany)

    1998-09-01

    The examples presented in this paper from diverse application areas of the chemical industry serve as an illustration of the many different ways in which wastes can be used for high-temperature processes in this branch. A review of the environmentally friendly concepts implemented at BASF AG in Ludwigshafen in the course of the past five years gives an idea of the immense potential opened up by a consistent application of the four-stage model for the prevention, reduction, and utilisation of wastes. In this period it was possible to reduce waste arisings by 34%, down from a potential 2 million tons, physically recycle 51%, and convert 11.5% to energy. This left a comparatively small fraction of 3.5%, or 70,000 tons, to be disposed of in an environmentally acceptable way. Furthermore, the amount of pollutants produced per tonne of products sold fell from 40.6 kg in 1987 to 6.7 kg in 1997. [Deutsch] Die Beispiele aus den unterschiedlichsten Anwendungsbereichen der chemischen Industrie koennen als Auswahl der vielfaeltigen Verwertungsmoeglichkeiten von Abfaellen in Hochtemperaturprozessen der Chemie betrachtet werden. Das immense Potential, das sich durch konsequente Anwendung des 4-Stufen-Modells zur Vermeidung, Verminderung und Verwertung von Abfaellen eroeffnet, zeigt sich in einer Fuenfjahresbilanz der umgesetzten Umweltschutzbetrachtungen in der BASF AG in Ludwigshafen. So konnten in diesem Zeitraum von potentiellen 2 Mio t Abfall/a ca. 34% vermieden und vermindert, 51% stofflich und 11,5% energetisch verwertet werden, so dass nur noch ein geringer Anteil von 3,5%, entsprechend ca. 70000 t/a, umweltgerecht entsorgt werden musste. Dies fuehrte auch zu einer drastischen Reduktion der auf der Tonne Verkaufsprodukt bezogenen Menge an umweltbelastenden Stoffen von 40,6 kg im Jahre 1987 auf 6,7 kg im Jahre 1997. (orig.)

  11. Diagnose und Therapie einer Depression im höheren Lebensalter – Einflüsse von Patienten- und Arztmerkmalen

    Science.gov (United States)

    von dem Knesebeck, Olaf; Bönte, Markus; Siegrist, Johannes; Marceau, Lisa; Link, Carol; McKinlay, John

    2013-01-01

    Zusammenfassung Studienergebnissee aus dem englischsprachigen Raum zeigen, dass diagnostische und therapeutische Entscheidungen von Hausärzten bei der Versorgung von depressiven Patienten systematischen Einflüssen unterliegen, und dass sowohl Merkmale des Arztes als auch des Patienten unabhängig vom Krankheitsbild Einfluss auf diese Entscheidungen haben. In der vorliegenden Arbeit werden Ergebnisse einer deutschen Studie präsentiert, in der die Einflüsse von Patienten- und Arztmerkmalen auf diagnostische und therapeutische ärztliche Entscheidungen bei einer Depression untersucht wurden. Unter Anwendung eines faktoriellen Experimentaldesigns spielten professionelle Schauspieler in Videofilmen die Rolle von Patienten, die Symptome für eine depressive Erkrankung äußern. In den Videofilmen, die alle auf einem identischen Skript basieren, wurden systematisch die Patientenmerkmale Alter (55 vs. 75 Jahre), Geschlecht und sozialer Status (Hausmeister vs. Lehrer) variiert. Die randomisierte Ärztestichprobe wurde nach dem Arztgeschlecht und professioneller Erfahrung ( 15 Jahre) geschichtet. Der Videofilm wurde insgesamt 128 niedergelassenen Ärzten für Allgemeinmedizin und hausärztlich tätigen Internisten in ihrer Praxis vorgespielt. Danach wurden die Ärzte zu unterschiedlichen Aspekten von Diagnose und Therapie befragt. Es wurde erhoben, ob der Arzt dem Patienten über das gezeigte Gespräch hinausgehende Fragen stellen würde, welche Diagnosen er für wahrscheinlich hält, wie sicher er sich mit seiner Diagnose ist, welche diagnostischen Tests er anordnen würde, ob er den Patienten überweisen würde oder ob er Medikamente verordnen oder ihm Empfehlungen zur Änderung seines Lebensstils geben würde. Die Ergebnisse weisen darauf hin, dass sowohl die Diagnose als auch die Therapie einer Depression durch niedergelassene Hausärzte in Deutschland nur geringfügig durch die untersuchten Merkmale der Patienten und der behandelnden Ärzte beeinflusst wird. PMID

  12. Hydraulic characterisation of karst systems with man-made tracers; Hydraulische Charakterisierung von Karstsystemen mit kuenstlichen Tracern

    Energy Technology Data Exchange (ETDEWEB)

    Werner, A.

    1998-07-01

    Tracer experiments using man-made tracers are common in hydrogeological exploration of groundwater aquifers in karst systems. In the present investigation, a convection-dispersion model (multidispersion model with consideration of several flow paths) and a single-cleft model (consideration of the diffusion between the cleft and the surrounding rock matrix) were used for evaluating tracer experiments in the main hydrological system of the saturated zone of karst systems. In addition to these extended analytical solutions, a numerical transport model was developed for investigating the influence of the transient flow rate on the flow and transport parameters. Comparative evaluations of the model approaches for the evaluation of tracer experiments were made in four different karst systems: Danube-Aach, Paderborn, Slowenia and Lurbach, of which the Danube-Aach system was considered as the most important. The investigation also comprised three supplementary experiments in order to enable a complete hydraulic characterisation of the system. (orig./SR) [Deutsch] Tracerversuche mit kuenstlichen Tracern sind eine haeufig eingesetzte Methode zur hydrogeologischen Erkundung von Karstgrundwasserleitern. In der vorliegenden Arbeit werden fuer die Auswertung von Tracerversuchen im Hauptfliesssystem der gesaettigten Zone von Karstsystemen ein Konvektion-Dispersions-Modell (Multi-Dispersions-Modell: Beruecksichtigung mehrerer Fliesswege) und vergleichend ein Einzelkluftmodell (Beruecksichtigung der Diffusion zwischen Kluft und umgebender Gesteinsmatrix) eingesetzt. Zusaetzlich zu diesen erweiterten analytischen Loesungen wurde ein numerisches Transportmodell entwickelt, welches ermoeglicht, den Einfluss der instationaeren Fliessrate auf die Stroemungs- und Transportparameter zu ueberpruefen. Die vergleichende Anwendung der Modellansaetze fuer die Auswertung von Tracerversuchen erfolgte in den vier verschiedenen Karstsystemen Donau-Aach, Paderborn, Slowenien und Lurbachsystem. Der

  13. Nasal Septum Perforation due to Methamphetamine abuse

    Directory of Open Access Journals (Sweden)

    Mehdi Bakhshaee

    2012-07-01

    Full Text Available Introduction: Spontaneous Perforation of the nasal septum is an uncommon condition. Nasal inhalation of substances such as cocaine has long been linked to this Perforation. Case Report: This report describes the case of a 46-year-old woman who was addicted to methamphetamine and who presented with perforation of the nasal septum.This is the first reported case of nasal septal necrosis linked to nasal inhalation of methamphetamine. Conclusions: Patient history and assurance regardingillegal drug consumption and abuse is a key point for fast and accurate diagnosis. The pathophysiology of drug-induced sinunasal disease and a review of the literature are also presented.

  14. Methods for safe and economical design of components of ABS/ABR braking systems in terms of operating stability; Methodik zur sicheren und wirtschaftlichen betriebsfesten Auslegung von Komponenten in ABS/ASR-Bremssystemen

    Energy Technology Data Exchange (ETDEWEB)

    Bacher-Hoechst, M. [Robert Bosch GmbH, Technisches Zentrum Schwieberdingen (Germany); Sonsino, C.M. [Fraunhofer-Institut fuer Betriebsfestigkeit (LBF), Darmstadt (Germany)

    1997-05-01

    The combination of hardware-in-the-loop simulators with stress calculation in terms of operating stability at Robert Bosch GmbH, as well as experience gathered at LBF Darmstadt with component in terms of operating stability, result in optimized design of hydraulic units for antilock systems (ABS) and acceleration skid control systems (ASC). Thus, both safety demands and economic demands are met. (orig./AKF) [Deutsch] Die kombinierte Anwendung von Hardware-In-The-Loop-Simulatoren mit betriebsfestigkeitsgerechter Belastungserfassung bei der Robert Bosch GmbH und die beim LBF Darmstadt vorliegenden Erfahrungen bei der betriebsfesten Bauteilauslegung fuehren zu einer optimierten Auslegung und Absicherung von Hydraulikaggregaten fuer Antiblockier- und Antriebsschlupfregelungssyteme (ABS,ASR). Die wesentlichen Schritte dieses Vorgehens wurden gezeigt. Auf diese Weise ist es moeglich, den Sicherheitsanforderungen derartiger Bauteile einerseits und den wirtschaftlich-technischen Rahmenbedingungen andererseits zu entsprechen. (orig./AKF)

  15. Quality management and reduction of processing time through automised preforming in the rotorblade manufacturing for wind turbines; Teilautomatisiertes preforming zur Qualitaetssicherung und Verkuerzung von Fertigungszeiten bei der Herstellung von Rotorblaettern von Windenergieanlagen

    Energy Technology Data Exchange (ETDEWEB)

    Doersch, C.; Ohlendorf, J.H.; Gebauer, I.; Mueller, D.H. [Bremer Institut fuer Konstruktionstechnik, Universitaet Bremen (Germany); Weigel, L. [Abeking Rasmussen Rotec GmbH and Co. KG, Lemwerder (Germany)

    2007-11-15

    Rotor blades of wind turbines are mainly manufactured from fibre reinforced plastics. These materials show an excellent performance concering the ratio of stiffness and weight. Basically the composite material of rotor blades is made out of glass fibres and thermosetting material. But growing technological and economical requirements to rotor blades by off-shore-application, in particular through increasing rotor blade diameter, have to meet successful. Although reduction of processing time and increased quality of rotor blades play a major role. To achieve the increasing requirements of the rotor blade manufacturing the Bremen Institute for Engineering Design and the rotor blade manufacturer Abeking and Rasmussen Rotec GmbH are working together on the handling and manufacturing of textile preforms. Preforms are made out of stacked and bonded dry textile layers and deposited in the mould as one textile part. Preforming allows the parallel processing of some manufacturing steps. This shows great advantages in the production of fibre reinforced plastics because of the long curing time of the resin component. This parallel processing is required to reach the aim of decreased overall cycle time. This essay is focussing on the handling of textiles and the textile preforming. Summarised aspects of quality management and economics in textile preforming will be discussed with the aim of automising the preforming process. (Abstract Copyright [2007], Wiley Periodicals, Inc.) [German] Rotorblaetter von Windenergieanlagen werden aufgrund des guten Verhaeltnisses von Steifigkeit und Gewicht zu grossen Teilen aus Faserverbundwerkstoffen gefertigt. Dabei kommen hauptsaechlich Glasfasern (GF) als verstaerkendes Material sowie duroplastische Harze als Matrix zur Anwendung. Um die wachsenden Herausforderungen des Offshore-Einsatzes von Windenergieanlagen, insbesondere die steigende Rotorblattgroesse, technisch und wirtschaftlich erfolgreich bewaeltigen zu koennen, wird die

  16. Characteristics of nasal-associated lymphoid tissue (NALT) and nasal absorption capacity in chicken.

    Science.gov (United States)

    Kang, Haihong; Yan, Mengfei; Yu, Qinghua; Yang, Qian

    2013-01-01

    As the main mucosal immune inductive site of nasal cavity, nasal-associated lymphoid tissue (NALT) plays an important role in both antigen recognition and immune activation after intranasal immunization. However, the efficiency of intranasal vaccines is commonly restricted by the insufficient intake of antigen by the nasal mucosa, resulting from the nasal mucosal barrier and the nasal mucociliary clearance. The distribution of NALT and the characteristic of nasal cavity have already been described in humans and many laboratory rodents, while data about poultry are scarce. For this purpose, histological sections of the chicken nasal cavities were used to examine the anatomical structure and histological characteristics of nasal cavity. Besides, the absorptive capacity of chicken nasal mucosa was also studied using the materials with different particle size. Results showed that the NALT of chicken was located on the bottom of nasal septum and both sides of choanal cleft, which mainly consisted of second lymphoid follicle. A large number of lymphocytes were distributed under the mucosal epithelium of inferior nasal meatus. In addition, there were also diffuse lymphoid tissues located under the epithelium of the concha nasalis media and the walls of nasal cavity. The results of absorption experiment showed that the chicken nasal mucosa was capable to absorb trypan blue, OVA, and fluorescent latex particles. Inactivated avian influenza virus (IAIV) could be taken up by chicken nasal mucosa except for the stratified squamous epithelium sites located on the forepart of nasal cavity. The intake of IAIV by NALT was greater than that of the nasal mucosa covering on non-lymphoid tissue, which could be further enhanced after intranasal inoculation combined with sodium cholate or CpG DNA. The study on NALT and nasal absorptive capacity will be benefit for further understanding of immune mechanisms after nasal vaccination and development of nasal vaccines for poultry.

  17. Appraisal of transverse nasal groove: a study.

    Science.gov (United States)

    Sathyanarayana, Belagola D; Basavaraj, Halevoor B; Nischal, Kuchangi C; Swaroop, Mukunda R; Umashankar, Puttagangu N; Agrawal, Dhruv P; Swamy, Suchetha S; Okram, Sarda

    2012-01-01

    Transverse nasal groove is a condition of cosmetic concern which awaits due recognition and has been widely described as a shallow groove that extends transversely over the dorsum of nose. However, we observed variations in the clinical presentations of this entity, hitherto undescribed in literature. We conducted a clinicoepidemiological study of transverse nasal lesions in patients attending our outpatient department. We conducted a prospective observational study. We screened all patients attending our out-patient department for presence of transverse nasal lesions, signs of any dermatosis and associated other skin conditions. One hundred patients were recruited in the study. Females (80%) predominated over males. Most patients were of 15-45 years age group (70%). Majority of the transverse nasal lesions were classical transverse nasal groove (39%) and others included transverse nasal line (28%), strip (28%), ridge (4%) and loop (1%). Seborrhoeic diathesis was the most common condition associated with transverse nasal lesion. Occurrence of transverse nasal line, strip, ridge and loop, in addition to classical transverse nasal groove implies that latter is actually a subset of transverse nasal lesions. Common association of this entity with seborrheic dermatitis, seborrhea and dandruff raises a possibility of whether transverse nasal lesion is a manifestation of seborrheic diathesis.

  18. Measurement of secretion in nasal lavage

    DEFF Research Database (Denmark)

    Bisgaard, H; Krogsgaard, O W; Mygind, N

    1987-01-01

    1. The amount of admixture in nasal lavage fluids was determined by addition of 99mTc labelled albumin, providing a correction factor for measurements of cellular material and humoral substances in nasal lavage return as well as a quantitative measure of nasal secretions. 2. Albumin was chosen...... as marker molecule, since only negligible amounts were absorbed or adsorbed to the mucosa during the nasal lavage. 3. Labelling of the albumin with 99mTc ensured an accuracy of measurements only limited by the precision of the weighing. The isotope allowed for the determination of the amount of admixed...... of the nose, yet not the oropharynx. 5. A dose related increase in nasal secretion harvested by the nasal lavage in 10 persons challenged with histamine chloride could be demonstrated by this technique. 6. It is concluded that the use of 99mTc-albumin in a nasal washing provides a safe, simple and quick...

  19. Measurement of secretion in nasal lavage

    DEFF Research Database (Denmark)

    Bisgaard, H; Krogsgaard, O W; Mygind, N

    1987-01-01

    1. The amount of admixture in nasal lavage fluids was determined by addition of 99mTc labelled albumin, providing a correction factor for measurements of cellular material and humoral substances in nasal lavage return as well as a quantitative measure of nasal secretions. 2. Albumin was chosen...... secretion to be carried out on the whole sample of lavage fluid, thereby avoiding the necessity of complete admixture between marker and lavage fluid which would be pertinent to marker molecules measured chemically. The radiation from a nasal lavage is minimal and the procedure is fully acceptable...... of the nose, yet not the oropharynx. 5. A dose related increase in nasal secretion harvested by the nasal lavage in 10 persons challenged with histamine chloride could be demonstrated by this technique. 6. It is concluded that the use of 99mTc-albumin in a nasal washing provides a safe, simple and quick...

  20. Rhinoplasty via the midface degloving approach for nasal deformity due to nasal polyps: A case report of Woakes’ syndrome

    Directory of Open Access Journals (Sweden)

    Misato Ueda, MD

    2017-09-01

    Full Text Available Nasal polyps are inflammatory proliferative tumors arising from the mucosa of the nasal cavity and paranasal sinuses. Although many cases concerning nasal polyps have been reported, those involving external nasal deformities are rare. We report a case of nasal polyposis filling the nasal cavity and paranasal sinuses, leading to external nasal and facial deformities. The condition above is known as Woakes’ syndrome, which is characterized by severe recurrent nasal polyps with deformity of the nasal pyramid, leading to broadening of the nose. We performed nasal osteotomy and facial bone-shaving via the midface degloving approach, which improved the patient’s facial appearance.

  1. Smart Polymers in Nasal Drug Delivery.

    Science.gov (United States)

    Chonkar, Ankita; Nayak, Usha; Udupa, N

    2015-01-01

    Nasal drug delivery has now been recognized as a promising route for drug delivery due to its capability of transporting a drug to systemic circulation and central nervous system. Though nasal mucosa offers improved bioavailability and quick onset of action of the drug, main disadvantage associated with nasal drug delivery is mucocilliary clearance due to which drug particles get cleared from the nose before complete absorption through nasal mucosa. Therefore, mucoadhesive polymeric approach can be successfully used to enhance the retention of the drug on nasal mucosal surface. Here, some of the aspects of the stimuli responsive polymers have been discussed which possess liquid state at the room temperature and in response to nasal temperature, pH and ions present in mucous, can undergo in situ gelation in nasal cavity. In this review, several temperature responsive, pH responsive and ion responsive polymers used in nasal delivery, their gelling mechanisms have been discussed. Smart polymers not only able to enhance the retention of the drug in nasal cavity but also provide controlled release, ease of administration, enhanced permeation of the drug and protection of the drug from mucosal enzymes. Thus smart polymeric approach can be effectively used for nasal delivery of peptide drugs, central nervous system dugs and hormones.

  2. Nasal morphological characteristics of the Serbian population

    Directory of Open Access Journals (Sweden)

    Jovanović J.

    2014-01-01

    Full Text Available The aim of this study was to determine the nasal parameters in the population of central Serbia and to compare them with those determined in earlier studies in different populations. The research was conducted on 496 randomly selected persons (262 males and 234 females, aged 18-65 years. The measured parameters were nasal height and nasal breadth and the standard spreading caliper with scale was used for measurements. There were significant differences in the nasal parameters between male and female subjects. The nasal breadth was 34.72 mm in females, and in the male population it was 36.7 mm. The mean values of nasal height were 52.6 mm and 54.32 mm in females and males, respectively. The nasal index in females and males was 66.01 and 67.56, respectively, and the mean value of the nasal index of all respondents was 66.78. After conducting the research it was concluded that the dominant nasal type in the population of the central part of Serbia is leptorrhine. The present study showed the existence of sexual dimorphism in nasal morphology. The data obtained in our study may be useful in anthropological and forensic research, as well as in cosmetic planning and reconstructive surgery.

  3. Nutzerorientiertes Management von materiellen und immateriellen Informationsobjekten

    OpenAIRE

    Hübsch, Chris

    2001-01-01

    Schaffung einer stabilen, erweiterbaren und skalierbaren Infrastruktur für die Bereitstellung von Diensten im Umfeld von Bibliotheken und ähnlichen wissensanbietenden Einrichtungen unter Verwendung von XML-RPC und Python.

  4. Chondrosarcoma of the nasal septum.

    Science.gov (United States)

    Indudharan, R; Das, P K; Azman, A A; Suhaiza, S

    1998-08-01

    A case of chondrosarcoma of the nasal septum is presented with the result of treatment. The patient was admitted for a growth in the nose of four years' duration. Fine needle aspiration for cytological examination was suggestive of squamous cell carcinoma. She was treated with lateral rhinotomy and wide excision followed by septorhinoplasty. Histological examination showed that the lesion was chondrosarcoma. The patient remained free of disease 26 months after surgery.

  5. Darstellung und Anwendung eines Bewertungsmodells im Rahmen des Controllings unter Beachtung der IAS/IFRS

    OpenAIRE

    Volkmann, Sebastian

    2005-01-01

    Die zunehmende Etablierung des Shareholder Value-Gedankens in Europa, die Rechnungslegung nach IAS/IFRS in Kombination mit der Forderung nach Konvergenz des internen sowie des externen Rechnungswesens erfordern die vertiefte Kapitalmarktorientierung von Unternehmen. Entsprechend werden in dieser Arbeit Ansätze diskutiert, die wertorientierte Unternehmensführung mit Hilfe eines Bewertungsmodells zu unterstützen, um Implementierungslücken auf Ebene des Konzern- oder Geschäftsbereichscontrolling...

  6. Primary nasal tuberculosis following blunt trauma nose

    Directory of Open Access Journals (Sweden)

    Kaushik Saha

    2014-01-01

    Full Text Available Primary nasal tuberculosis is a rare disease with nearly 40 cases reported. Our patient was a young male presented with left sided nasal obstruction, anosmia and occasional epistaxis for last 7 weeks after 6 months of blunt trauma nose. Contrast enhanced computed tomography of the para nasal sinuses showed increased soft-tissue density with contrast enhancement in the left maxillary antrum with extension through left osteomeatal foramen to the left nasal cavity along with further extension through choana to nasopharynx resulting in partial obliteration of the nasopharyngeal airway. Nasal endoscopy revealed a sessile polypoidal pinkish mass arising from the left osteomeatal foramen. Histopathological examination of excisional biopsy of that area showed caseating granuloma. Our patient diagnosed as primary nasal tuberculosis following trauma and treated with anti-tubercular chemotherapy.

  7. Nasal morphological characteristics of the Serbian population

    OpenAIRE

    Jovanović J.; Jeremić D.; Jovanović B.; Vulović Maja; Sazdanović P.; Sazdanović Maja; Ognjanović Neda; Stojadinović D.; Jeremić Katarina; Marković N.; Živanović-Mačužić Ivana

    2014-01-01

    The aim of this study was to determine the nasal parameters in the population of central Serbia and to compare them with those determined in earlier studies in different populations. The research was conducted on 496 randomly selected persons (262 males and 234 females), aged 18-65 years. The measured parameters were nasal height and nasal breadth and the standard spreading caliper with scale was used for measurements. There were significant differences in ...

  8. Nasal Myiasis in Hinduism and Contemporary Otorhinolaryngology.

    Science.gov (United States)

    Bosmia, Anand N; Zimmermann, Terence M; Griessenauer, Christoph J; Shane Tubbs, R; Rosenthal, Eben L

    2017-08-01

    Various case reports on nasal myiasis written during the 1990s and 2000s state that nasal myiasis, which is known as peenash among South Asian natives, is a form of divine punishment in Hindu mythology, but do not provide citations from Hindu scriptures that would suggest this interpretation. This paper aims to discuss the phenomenon of peenash in a historical context by examining medical literature written during the nineteenth and early twentieth centuries, to identify Hindu texts contributing to the belief of some Hindus that nasal myiasis is a form of divine punishment, and to provide an overview of contemporary treatment for and management of nasal myiasis.

  9. Immediate effect of benzalkonium chloride in decongestant nasal spray on the human nasal mucosal temperature.

    Science.gov (United States)

    Lindemann, J; Leiacker, R; Wiesmiller, K; Rettinger, G; Keck, T

    2004-08-01

    Benzalkonium chloride is a preservative commonly used in nasal decongestant sprays. It has been suggested that benzalkonium chloride may be harmful to the nasal mucosa. Decongestion with the vasoconstrictor xylometazoline containing benzalkonium chloride has been shown to cause a significant reduction of the nasal mucosal temperature. The purpose of the present study was to determine the short-term influence of xylometazoline nasal spray with and without benzalkonium chloride on the nasal mucosal temperature. Healthy volunteers (30) were included in the study. Fifteen volunteers received xylometazoline nasal spray (1.0 mg/mL) containing benzalkonium chloride (0.1 mg/mL) and 15 age-matched subjects, received xylometazoline nasal spray without benzalkonium chloride. Using a miniaturized thermocouple the septal mucosal temperature was continuously measured at defined intranasal detection sites before and after application of the nasal spray. The mucosal temperature values did not significantly differ between the group receiving xylometazoline containing benzalkonium chloride and the group receiving xylometazoline spray without benzalkonium chloride before and after decongestion (P > 0.05). In both study groups septal mucosal temperatures significantly decreased after decongestion (P reduction of the nasal mucosal blood flow following vasoconstriction. This study indicates that benzalkonium chloride itself does not seem to influence nasal blood flow and nasal mucosal temperature in topical nasal decongestants.

  10. Cartilage grafting in nasal reconstruction.

    Science.gov (United States)

    Immerman, Sara; White, W Matthew; Constantinides, Minas

    2011-02-01

    Nasal reconstruction after resection for cutaneous malignancies poses a unique challenge to facial plastic surgeons. The nose, a unique 3-D structure, not only must remain functional but also be aesthetically pleasing to patients. A complete understanding of all the layers of the nose and knowledge of available cartilage grafting material is necessary. Autogenous material, namely septal, auricular, and costal cartilage, is the most favored material in a free cartilage graft or a composite cartilage graft. All types of material have advantages and disadvantages that should guide the most appropriate selection to maximize the functional and cosmetic outcomes for patients. Copyright © 2011 Elsevier Inc. All rights reserved.

  11. Distilled water nasal provocation in hyperreactive patients.

    Science.gov (United States)

    Baudoin, T; Anzic, S A; Kalogjera, L

    1999-01-01

    Nonisotonic aerosol may act as a provocation agent in the upper and lower airways of hyperreactive individuals. The purpose of the study was to compare the results of nasal challenge with distilled water in patients with allergic rhinitis to those with noninfective nonallergic rhinitis (NINAR), with respect to the potential clinical use of the obtained data. A group of 68 ambulatory patients with allergic rhinitis or NINAR (39 perennial allergic, 6 seasonal, 23 NINAR) were challenged with 10 mL of distilled water aerosol after the baseline active anterior rhinomanometry. Patients with nasal polyposis at endoscopy, significant unilateral septal deviation, positive bacteriologic swab, recent nasal surgery, and uncertain anamnestic data about the medication taken 6 weeks before the provocation were excluded from the study. After 10 minutes of nasal provocation, rhinomanometry was repeated to assess the response. In 15 patients of the perennial allergic group, the same measurements were performed after a 2-week oral antihistamine and topical steroid therapy. Nasal resistance was significantly increased on the more patent side of the nose after nasal provocation with distilled water aerosol in allergic patients in comparison to the nasal resistance before provocation. In the patients with NINAR, the provocation resulted in a significant rise on the more patent side, but the total nasal airway resistance (NAR) levels were also significantly increased. The systemic antihistamine and topical steroid 2-week therapy in patients with perennial allergic rhinitis significantly reduced the response to nasal distilled water provocation. Nasal provocation with distilled water aerosol is a cheap, simple, and acceptable method that provides useful clinical data on the level of nonspecific nasal hyperreactivity and the therapy success.

  12. Beeinflussung des Angebots im Lebensmitteleinzelhandel durch Konsumenteninformationen: Eine Anwendung auf Basis der Theory of Planned Behavior

    OpenAIRE

    Mecking, Rebecca-Ariane

    2015-01-01

    Von Informationen, die Konsumenten z. B. über Kundenkarten dem Lebensmitteleinzelhandel (LEH) mitteilen, können auch sie selber profitieren, indem das Angebot besser an ihre Bedürfnisse angepasst wird. Basierend auf der Theory of Planned Behavior untersucht diese Arbeit, welche Faktoren entscheidend dafür sind, ob ein Konsument dem LEH zum Zwecke der Einflussnahme Informationen mitteilen möchte. Wichtig sind das Bewusstsein um diese Chance und ihre positiven Folgen. Sorgen um die Privatsphäre...

  13. Effect of the nasal cycle on congestive response during bilateral nasal allergen provocation

    Directory of Open Access Journals (Sweden)

    Tomasz Gotlib

    2014-06-01

    Full Text Available Background. Bilateral nasal allergen provocation usually produces more pronounced obstruction of one nasal passage. It was found that this could be related to the stage of the nasal cycle before the provocation. objective. To discover whether the stage of the nasal cycle is decisive for asymmetry in congestive response observed during bilateral allergen nasal provocation. methods. Two bilateral nasal allergen provocations were performed in a group of 26 pollen-sensitive volunteers. Acoustic rhinometry measurements were taken during the nasal cycle, and then after the provocation. A cross-sectional area at the level of the inferior turbinate (CSA-2 was measured. Consecutive challenges were performed in the opposite phase of the nasal cycle: the side which had been wide just before the first challenge, was narrow before the second provocation. results. Asymmetry in CSA-2 reduction between the nasal passages was observed in most cases. Significant difference was observed between mean CSA-2 reduction rate (reactivity of the side that responded with greater congestion, and the opposite side. No significant difference was found in mean CSA-2 reduction rate between the side which was narrow, and the side which was wide before provocation. conclusions. Asymmetry of congestive response during bilateral nasal allergen provocation is not dependent on the stage of the nasal cycle preceding the challenge.

  14. NASAL INVERTED PAPILLOMA OF UNUSUAL ORIGIN

    OpenAIRE

    kasim s. kasim; Universiti Tunku Abdul Rahman; BALWANT SINGH GENDEH

    2013-01-01

    Two cases of Schneiderian papilloma of the nasal septum are presented. The condition is rare, as indicated by a review of previously published cases. The clinical course of the lesion suggests that it behaves like Schneiderian papillomas elsewhere in the nasal cavity and paranasal sinuses. The need for aggressive surgical management and careful follow-up is emphasized.

  15. Nasal mucociliary transport in laryngectomees

    International Nuclear Information System (INIS)

    Pavia, J.; Garcia, A.; Abello, R.; Herranz, R.; Franch, M.; Espana, R. de

    1986-01-01

    A study has been carried out to assess the mucociliary function of nasal mucosa in 30 patients: 16 had undergone surgery due to larynx malignancy and the remaining 14 were divided in two groups. The first group was composed of seven patients suffering from larynx cancer but not operated, and the second group of seven had pathology not related to the airways (control group). The method used a sup(99m)technetium sulphur colloid drop deposited on the nasal mucosa of one nostril. To calculate the rate of transport, a new method of quantification has been introduced, based on the formation of a parametric image. The mean velocity in laryngectomees was 3.6 mm/min (range 1.1-6.4). It was compared with the group of 14 patients without tracheostomy (mean 5.3, range 3.3-8.2). An impaired student's-t-test gave a significant difference between both groups (P<0.005). The comparison between patients with nonoperated larynx cancer and normals have a nonsignificant difference. The 16 operated patients were arbitrarily divided into two groups as per the time elapsed from laryngectomy; seven were studied within the first 3 years of operation and seven other patients after this term. The comparison between them was not significant. (orig.)

  16. Esthesioneuroblastoma of the nasal cavity.

    Science.gov (United States)

    Hollen, Tyler R; Morris, Christopher G; Kirwan, Jessica M; Amdur, Robert J; Werning, John W; Vaysberg, Mikhail; Mendenhall, William M

    2015-06-01

    Esthesioneuroblastoma is an uncommon cancer of the nasal cavity. We describe the outcomes for 26 patients treated with curative intent with photon radiotherapy (RT) at the University of Florida. Between May 1972 and June 2007, 26 patients received RT for previously untreated esthesioneuroblastoma of the nasal cavity. Sixteen patients were males and 10 were females with a median age of 55 years (range, 3 to 82 y). The modified Kadish stage distribution was: B, 7 patients; C, 17 patients; and D, 2 patients. Treatment modalities included the following: definitive RT, 5 patients; preoperative RT, 2 patients; and postoperative RT after resection, 19 patients. Elective neck irradiation (ENI) was performed in 17 (71%) of 24 N0 patients. Rates of local control, cause-specific survival, and absolute overall survival at 5 years were 79%, 72%, and 69%, respectively. Overall survival among patients treated with definitive RT was 20% at 5 years, compared with 81% among those who underwent surgery and adjuvant RT (P=0.01). One (6%) of 17 patients who received ENI developed a recurrence in the neck and was successfully salvaged. Ultimate neck control was 100% at 5 years for patients who received ENI versus 69% among those not receiving ENI (P=0.0173). Resection combined with adjuvant RT is more effective than surgery or RT alone in the treatment of esthesioneuroblastoma. ENI reduces the risk of regional relapse in patients with Kadish stage B and C cancers.

  17. [Clinical and anatomical characteristic of nasal injuries].

    Science.gov (United States)

    Surikov, E V; Ivanets, I V

    2009-01-01

    A fracture of nasal bones is becoming a very common injury due to the increasingly greater number of car accidents and aggravated criminal situation. A total of 500 cases of nasal fracture associated with external deformities were included in the present study. The following kinds of deformities were identified: unilateral retraction, lateral displacement of the entire dorsum of the nose, and depressed comminuted fracture. Rhinoscopy revealed in addition such abnormalities associated with septal fracture as submucous hemorrhage, pathological mobility of the pyramid, deflection of the nasal septum at an acute angle. All in all, four types of nasal septum fractures were distinguished depending on the shape and localization of the fracture line. Two of them resulted in marked impairment of nasal breathing while two others required surgical intervention in the acute period after the injury.

  18. Nasal Drug Delivery in Traditional Persian Medicine

    Science.gov (United States)

    Zarshenas, Mohammad Mehdi; Zargaran, Arman; Müller, Johannes; Mohagheghzadeh, Abdolali

    2013-01-01

    Background Over one hundred different pharmaceutical dosage forms have been recorded in literatures of Traditional Persian Medicine among which nasal forms are considerable. Objectives This study designed to derive the most often applied nasal dosage forms together with those brief clinical administrations. Materials and Methods In the current study remaining pharmaceutical manuscripts of Persia during 9th to 18th century AD have been studied and different dosage forms related to nasal application of herbal medicines and their therapeutic effects were derived. Results By searching through pharmaceutical manuscripts of medieval Persia, different nasal dosage forms involving eleven types related to three main groups are found. These types could be derived from powder, solution or liquid and gaseous forms. Gaseous form were classified into fumigation (Bakhoor), vapor bath (Enkebab), inhalation (Lakhlakheh), aroma agents (Ghalieh) and olfaction or smell (Shomoom). Nasal solutions were as drops (Ghatoor), nasal snuffing drops (Saoot) and liquid snuff formulations (Noshoogh). Powders were as nasal insufflation or snorting agents (Nofookh) and errhine or sternutator medicine (Otoos). Nasal forms were not applied only for local purposes. Rather systemic disorders and specially CNS complications were said to be a target for these dosage forms. Discussion While this novel type of drug delivery is known as a suitable substitute for oral and parenteral administration, it was well accepted and extensively mentioned in Persian medical and pharmaceutical manuscripts and other traditional systems of medicine as well. Accordingly, medieval pharmaceutical standpoints on nasal dosage forms could still be an interesting subject of study. Therefore, the current work can briefly show the pharmaceutical knowledge on nasal formulations in medieval Persia and clarify a part of history of traditional Persian pharmacy. PMID:24624204

  19. Von der Vielfalt einer Institution

    OpenAIRE

    Kabaum, Marcel; Buck, Marc Fabian

    2013-01-01

    Von der Vielfalt von Universitäten bzw. higher education institutions (HEIs) zu sprechen heißt, sich dem Dickicht an Komplexität zu stellen, das sich zwischen ihren Ideen und Realitäten ausbreitet. Der Text führt in den Sammelband "Ideen und Realitäten von Universitäten" ein und hebt die verschiedenen disziplinären Sichtweisen sowie die internationale Breite - Deutschland, Südamerika, USA, Afghanistan und China - der Beiträge hervor. (DIPF/Orig.)

  20. Dimensioning of activation systems using submerged membranes at municipal sewage treatment plants; Bemessung von Membranbelebungsanlagen beim Einsatz zur Reinigung kommunaler Abwaesser

    Energy Technology Data Exchange (ETDEWEB)

    Ohle, P.; Dorgeloh, E. [Technische Hochschule Aachen (DE). Inst. fuer Siedlungswasserwirtschaft (ISA)

    1999-07-01

    Dimensioning of conventional activation systems in Germany as a rule relies on instruction sheet A131 of the Abwassertechnische Vereinigung or follows the Hochschulgruppen approach (HSG). They contain recommendations as to the size of the nitrification and denitrification zones, the amount of oxygen supplied and sludge production, and the size of the final sedimentation tank. For the use of sludge activation techniques by means of submerged membranes at municipal sewage treatment plant there so far do not exist any clues to dimensioning that make allowance for the modified boundary conditions. The present paper analyses instruction sheet A131 for its suitability as a basis in the dimensioning of sludge activation systems with submerged membranes at municipal sewage treatment plant. Then the dimensioning instructions are modified to suit the changed boundary conditions, and recommendations for the dimensioning of activation systems with submerged membranes on the basis of extensive studies carried out at the Institut fuer Siedlungswasserwirtschaft ISA of Aachen Technical University RWTH are given. (orig.) [German] Die Bemessung konventioneller Belebungsverfahren erfolgt in Deutschland i.d.R. auf der Grundlage des Arbeitsblatts A 131 der Abwassertechnischen Vereinigung bzw. nach dem Hochschulgruppenansatz (HSG). Sie enthalten Empfehlungen bezueglich der Dimensionierung von Nitrifikations- und Denitrifikationszone, Sauerstoffversorgung, Schlammproduktion und Nachklaerbecken. Fuer den Einsatz von Membranbelebungsanlagen in kommunalen Klaeranlagen existieren bislang keine Bemessungshinweise, die den veraenderten Randbedingungen Rechnung tragen. Der vorliegende Beitrag analysiert das Arbeitsblatt A 131 in Hinsicht auf die Moeglichkeit zur Anwendung fuer die Bemessung von Membranbelebungsanlagen beim Einsatz zur kommunalen Abwasserreinigung. Im Weiteren erfolgt die Modifikation der Bemessungshinweise hinsichtlich der geaenderten Randbedingungen und die Angabe von

  1. Alejandro Von Humboldt

    Directory of Open Access Journals (Sweden)

    Gerardo Paz Otero

    1965-09-01

    Full Text Available Diverso fue y sigue siéndolo, el destino de los dos hermanos Humboldt, Guillermo y Alejandro. Sino que se inicia con el nacimiento: Guillermo, el mayor, nace el 22 de junio de 1767 en Potsdam, residencia de los emperadores prusianos, la ciudad de los palacios imperiales, el imperio del militarismo germano; su cuna se meció cerca al palacete de Sans-Soussi, donde Federico el Grande forja ba el poderío de Prusia, cultivaba las ciencias y las artes, anfitrionaba a los intelectuales de Europa, y era "vasallo espiritual de Volta ire", según la aguda frase de Goethe. Alejandro viene al mundo dos años después (14 de septiembre de 1769 en Berlín, en la casa burguesa de la Jagerstrasse (calle del cazador que su madre Elizabeth von Humboldt heredara de su primer esposo.

  2. The use of radioactive materials in German schools. Obstacles and chances; Anwendung von radioaktiven Stoffen in Schulen in Deutschland. Hindernisse und Chancen

    Energy Technology Data Exchange (ETDEWEB)

    Vahlbruch, Jan-Willem [Hannover Univ. (Germany). Inst. fuer Radiooekologie und Strahlenschutz

    2015-07-01

    The basics for the understanding of radioactivity and radioprotection are set in the secondary school. Therefore the German-Swiss Radiation Protection Association already is trying to support the appropriate teaching of relevant topics in school for a long time. Unfortunately experiments with radioactive material are hampered in Germany by complex and confusing legislation. In this contribution the framework is described which is given by the German legislation for the use of radioactive sources in secondary schools. Additionally proposals for different simple experiments with radioactivity are presented which can be easily implemented in teaching and alternative methods are introduced like e.g. virtual experiments.

  3. Application of biotests for the characterization of exposure pathways for endocrine disrupters from plastics; Anwendung von Biotests zur Charakterisierung der Expositionspfade fuer Umwelthormone aus Kunststoffen

    Energy Technology Data Exchange (ETDEWEB)

    Wagner, Martin; Oehlmann, Joerg [Frankfurt Univ., Frankfurt am Main (Germany). Abteilung Aquatische Oekotoxikologie

    2011-12-15

    The present project aims to characterise the exposure pathways for endocrine disruptors from plastic materials. A bioassay-based approach was employed to investigate and characterise the endocrine activity. Migration studies with food packaging and plastic preforms document the leaching of estrogen-like compounds from several types of plastic in the Yeast Estrogen Screen and the E-Screen. Additionally, anti-estrogenic activity was predominant in many samples. The detection of complex migration profiles provides evidence for the leaching of several, diverse-acting endocrine disruptors. Moreover, extracts of plastic food packaging exhibited agonistic activity on the estrogen receptor, retinoid X receptor, and vitamin D receptor. A theoretical exposure assessment for marine molluscs implies that endocrine disruptors from plastic might induce relevant effect in the environment. Within the exemplary investigation of bottled mineral water, 60% of the products were characterised as significantly estrogenic using the YES and E-Screen. These in vitro data point to the plastic packaging being one source of estrogenic contamination. An in vivo study employing the estrogen-sensitive model organism Potamopyrgus antipodarum supports this hypothesis. By using several analytical techniques (GC-MS, LC-MS/MS) we identified several well-known endocrine disruptors in bottled water and the plastic material, e.g. numerous phthalates and phenols. Moreover, potent antagonists of the estrogen and androgen receptor were extracted from bottled water. In a non-target analysis (Orbitrap-MS) a compound with the exact mass of 363.1992 [M+H{sup +}] correlated highly significantly with the biological activity. On the basis of the methods optimised and applied within the project we elaborated a set of aspects that are crucial for the applicability of bioassays to characterise the endocrine activity of complex samples. Employing a bioassay-based approach we provide evidence for the presence and migration of endocrine disruptors from plastic materials. In that sense, polymers represent a relevant but currently neglected source of human and environmental exposure to endocrine active compounds. Concerning the identification and toxicological characterisation of those chemicals, there is substantial need for further research. (orig.)

  4. DIE NEUREGELUNG DES IFRS 10 ZUR ABGRENZUNG DES KONSOLIDIERUNGSKREISES – DIE ANWENDUNG DES EINHEITLICHEN BEHERRSCHUNGSMODELS AUF DIE ERFASSUNG VON STRUKTURIERTEN UNTERNEHMEN IM KONZERNABSCHLUSS

    OpenAIRE

    Markus Häfele

    2013-01-01

    In the past entities varied in their application of the control concept (IAS 27 and SIC-12) in circumstances in which a reporting entity controls another entity but holds less than a majority of the voting rights of the entity, and in circumstances involving agency relationships (IFRS 10.IN3). This conflict between IAS 27 and SIC-12 had led to inconsistent application of the concept of control. IAS 27 required the consolidation of entities that are controlled by a reporting entity, and it def...

  5. Application of SiC masses as tube liners in municipal incinerators. Anwendung von SiC-Massen fuer Rohrverkleidungen in kommunalen Muellverbrennungsanlagen

    Energy Technology Data Exchange (ETDEWEB)

    Jeon, In Soo.

    1993-09-02

    Phosphate-bonded SiC masses with different additives were investigated. The reference mass was a SiC mass consisting of 90% by mass of SiC and 10% by mass of Al[sub 2]O[sub 3]. The reactive alumina ([alpha]-Al[sub 2]O[sub 3]) served as reaction partner for the aluminium phosphate binder. The physical and thermomechanical properties as well as the corrosion resistance of the developed SiC masses were investigated, and the reactions of the additives with the aluminium phosphate binder were investigated. The best combination of properties required of a refractory liner for waste incinerators was found in masses with Si[sub 3]N[sub 4] additives. These masses have optimal physical and thermomechanical properties and a high resistance to the corrosive gases and alkaline slags produced in modern incinerators. (orig./EF)

  6. Untersuchungen zur Expansion, funktionellen Charakterisierung und kontinuierlichen Bereitstellung von Hepatocyten für die Anwendung in bioartifiziellen Leberunterstützungssystemen

    OpenAIRE

    Iding, Kai

    2001-01-01

    Der vollständige Funktionsverlust der Leber kann in der modernen Medizin bisher nur durch den Austausch des funktionsuntüchtigen gegen ein gesundes Organ, d.h. durch eine Lebertransplantation behandelt werden. Da es jedoch weit mehr transplantationsbedürftige Patienten gibt als geeignete Spenderorgane zur Verfügung stehen, gibt es weltweite Anstrengungen zur Entwicklung alternativer Behandlungsmethoden. Nach bisherigem wissenschaftlichen Erkenntnisstand ist die bioartifizielle Leberunterst...

  7. Control-technical optimization of topped denitrification through fuzzy control; Regelungstechnische Optimierung der vorgeschalteten Denitrifikation durch Anwendung von Fuzzy-Control

    Energy Technology Data Exchange (ETDEWEB)

    Meyer, U. [Hydroplan Ingenieurgesellschaft, Worms (Germany); Poepel, H.J. [Technische Univ. Darmstadt (Germany). Inst. WAR - Wasserversorgung, Abwassertechnik, Abfalltechnik, Umwelt- und Raumplanung

    1999-07-01

    The present paper describes complex fuzzy systems for controlling nitrogen elimination at plants with topped denitrification. For the design and testing of the fuzzy systems, dynamic simulation calculations and experimental tests were carried out in a semi-technical pilot plant. The controlling fuzzy systems indicate the supposed oxygen values for individual tank areas and the most appropriate partitioning of the activated sludge tank (anoxic/aerobic zone) as a function of the input quantities used. It is established that, with the more flexible control behaviour, a more stable nitrogen elimination and, at the same time, a cut in the amount of air transferred to the system can be attained in comparison with a conventional control. (orig.) [German] Im Rahmen dieses Beitrags werden komplexe Fuzzy-Systeme zur Regelung der Stickstoffelimination in Anlagen mit vorgeschalteter Denitrifikation vorgestellt. Zum Entwurf und zur Erprobung der Fuzzy-Systeme wurden dynamische Simulationsrechnungen und experimentelle Untersuchungen an einer halbtechnischen Versuchsanlage durchgefuehrt. Die uebergeordneten Fuzzy-Systeme geben in Abhaengigkeit der verwendeten Eingangsgroessen Sauerstoffsollwerte fuer die einzelnen Beckenbereiche und die jeweils guenstigste Aufteilung des Belebungsbeckens (anoxische/aerobe Zone) vor. Die Ergebnisse zeigen, dass durch das flexible Reglerverhalten eine stabilere Stickstoffelimination und gleichzeitig eine Einsparung an eingetragener Luftmenge im Vergleich zu einem konventionellen Regelsystem erreicht werden kann. (orig.)

  8. Deep desulfurization of jet fuel for applications in mobile fuel cell systems; Tiefentschwefelung von Flugturbinenkraftstoffen fuer die Anwendung in mobilen Brennstoffzellensystemen

    Energy Technology Data Exchange (ETDEWEB)

    Wang, Yong

    2012-07-01

    Fuel cell powered APUs are promising for the on-board electricity supply in heavy vehicles, aircraft and ships because of their high efficiency and low emission of pollutants. The catalytical reforming with subsequent gas processing units is applied to operate the fuel cell system with onboard available fuels. Within the reformer the liquid fuel is converted into a hydrogen-rich synthesis gas in the presence of metal catalysts. However, an on-board desulfurization of fuels is required to avoid the deactivation of catalysts in the fuel processing unit as well as in the fuel cell. The present work aims at developing a technically feasible deep desulfurization process for fuel cell powered APUs with theoretical and experimental study as well as procedural analysis. The focus of the work is on the desulfurization of jet fuels in liquid phase, since the reformer currently developed in IEK-3 is designed for aviation applications of fuel cell APUs and it can only be operated by liquid jet fuels. In addition, the desulfurization of marine gas oil was investigated to fulfill the sulfur requirement of the fuels for the application of fuel cell A PUs for inland navigation. In the petroleum industry, low-sulfur fuels are often obtained by hydrodesulfurization and the S-Zorb Process. However, these conventional methods are highly inconvenient for reducing sulfur compounds to the desired level in a mobile fuel cell system, since improvements of the desulfurization efficiency are limited by increasingly severe operating conditions and escalating costs. Moreover, the hydrodesulfurization and the S-Zorb Process are not suitable for mobile applications, since hydrogen recycling is required, which is not possible with H{sub 2} syngas. To this end, a large number of processes discussed in the literature were assessed with regard to their application in fuel cell APUs. Three potentially suitable processes were selected: pervaporation, adsorption, and hydrodesulfurization with pre-saturation. Within a series of experiments in the laboratory, these processes were investigated with respect to their desulfurization ability and durability, while the required heat amount and electrical energy demand were determined by modeling and simulation. Subsequently, the potential of the desulfurization processes for technical applications were evaluated by a procedural and energetic analysis. As a result, the hydrodesulfurization with presaturation is most suitable for desulfurization of jet fuels for the application of fuel cell driven APUs in aircraft. A combination of pervaporation and adsorption is although applicable for the desulfurization of jet fuel and marine gas oil, more research work is required to increase the long-term stability of the membrane material. (orig.)

  9. Clinical use of 'ROTOP-NEUROSPECT' in several brain diseases. Die klinische Anwendung von 'ROTOP-NEUROSPECT' bei verschiedenen hirnorganischen Erkrankungen

    Energy Technology Data Exchange (ETDEWEB)

    Wuensche, A.; Kaempfer, I.; Loessner, J.; Wagner, A.; Dietrich, J.; Strauss, I.; Neumann, G.; Otto, L.; Koegler, A.; Schenk, S.; Schneider, G. (Leipzig Univ., Klinik fuer Radiologie, Abt. Nuklearmedizin (Germany) Leipzig Univ. (Germany). Klinik fuer Neurologie Leipzig Univ. (Germany). Klinik fuer Neurochirurgie Bezirkskrankenhaus fuer Psychiatrie, Leipzig-Doesen (Germany))

    1990-01-01

    We proofed the suitibility of ROTOP-NEUROSPECT (R*) (HMPAO) from Rossendorf for consideration of disturbed brain circulation in 42 patients. Results we compared with morphological methods (X-ray computing tomography, angiography) and with clinical and neurological findings. We found often a disturbed brain circulation in emission computing tomography (SPECT) before morphological changes in X-ray computing tomography (CT). ROTOP-NEUROSPECT (R*) from Rossendorf is very well for consideration of disturbed brain circulation, we did not see quality differences between ROTOP-NEUROSPECT and CERETEC from Amersham. Activity accumulations in the liver and gall of both radiopharmaceuticals did not influence the test, because of the big distance to the brain. (orig.).

  10. Application of molecular calcium compounds in catalysis and hydrogen storage; Anwendung von molekularen Calcium-Verbindungen in der Katalyse und der Wasserstoffspeicherung

    Energy Technology Data Exchange (ETDEWEB)

    Spielmann, Jan

    2010-07-20

    1. Applications in catalysis: In the course of this work new catalytic applications of calcium compounds and in particular hydrocarbon-soluble calcium hydride species have been investigated. The complex [(DIPP-nacnac)CaH(THF)]2 (1, DIPP-nacnac = HC[C(Me)N-2,6-(i-Pr)-C6H3]2) served as a model system to test reactivity of the calcium hydride in stoichiometric reactions on a molecular level. It has been found that the hydroboration of conjugated alkenes with catecholborane can be accelerated considerably by using catalytic amounts of calcium complexes. However it was shown that calcium hydride species catalyze the decomposition of catecholborane to BH3 which is probably the catalytically active species. Investigations on the catalytic hydrosilylation of ketones have demonstrated that calcium complexes are efficient catalysts for this reaction. In the proposed catalytic cycle of this reaction six-coordinate hypervalent silicon species play a crucial role. Furthermore it has been shown that molecular calcium compounds are catalysts for the hydrogenation of conjugated alkenes with H2 under relatively mild conditions (20 bar H2, 20 C). Both steps in the proposed catalytical cycle i.e. addition of a metal hydride to the C=C double bond and a heterolytic cleavage of H2 by a calcium alkyl compound have been confirmed experimentally. 2. Applications in hydrogen storage: Ligand stabilized metal amidoborane complexes in the form of (DIPP-nacnac)MNH(R)BH3(THF)x (M = Ca, Mg; R = H, Me, i-Pr, 2,6-(i-Pr)-C6H3; x = 0, 1, 2) have been synthesized and structurally characterized. These complexes are model systems for the metal amidoborane compounds M(NH2BH3)n (M = Li, Na, n = 1; M = Ca, n = 2), which are potential high capacity hydrogen storage materials. To get insights in their dehydrogenation mechanisms the thermal decomposition of the model compounds was investigated in solution. This allowed for the first isolation of well-defined dehydrogenated products which have been structurally characterized. Depending on the metal and the sterical bulk of the substituent R the decomposition resulted in the clean formation of complexes with either a central dianionic [N(R)-BH-N(R)-BH3]2--unit (R = H, Me, i-Pr), a compound containing a borylamide [N(R)=BH2]- (R = 2,6-(i Pr)-C6H3) or a metal hydride complex. For the observed products mechanisms of their formation have been proposed and experimentally confirmed. In these mechanisms metal hydride species play a key role. The favoured decomposition pathway leads to formation of compounds with the central dianionic [N(R)-BH-N(R)-BH3]2--unit. Additionally a magnesium-catalyzed synthetic route to a bis(amino)borane HB[NH(DIPP)]2 has been developed which can form a novel boramidinate ligand {l_brace}HB[N(2,6-(i-Pr)-C6H3)]2{r_brace}2- by double deprotonation. Furthermore a preparative useful synthetic route to zinc and aluminium hydride complexes based on the use of amidoborane compounds has been described. By using novel bis({beta}-diketiminate) ligands it has been possible to prepare dinuclear magnesium amidoborane complexes. The investigation of their thermal decomposition gave important information on aggregation effects of the complexes during the dehydrogenation. As a decomposition product of a N-substituted, dinuclear magnesium amidoborane complex a tetranuclear magnesium hydride complex has been isolated in low yields. Alternatively such compounds have been prepared in good yields by reaction of a n butylmagnesium precursor with phenylsilane. This synthetic approach allowed also the preparation of an octanuclear magnesium hydride complex with a central paddle-wheel shaped [Mg8H10]-unit. These multinuclear magnesium hydride complexes could be considered as ligand-stabilized forms of MgH2 and could be valuable model systems for investigations on MgxHy-hydrogen storage materials. (orig.)

  11. Comparison of Early-period Results of Nasal Splint and Merocel Nasal Packs in Septoplasty

    Science.gov (United States)

    Bingöl, Fatih; Budak, Ali; Şimşek, Eda; Kılıç, Korhan; Bingöl, Buket Özel

    2017-01-01

    Objective Several types of nasal packs are used postoperatively in septoplasty. In this study, we compared two commonly used nasal packing materials, the intranasal septal splint with airway and Merocel tampon, in terms of pain, bleeding, nasal obstruction, eating difficulties, discomfort in sleep, and pain and bleeding during removal of packing in the early period. Methods The study group included 60 patients undergoing septoplasty. Patients were divided into two groups (n=30 in each group). An intranasal splint with airway was used for the patients in the first group after septoplasty, while Merocel nasal packing was used for the second group. Patients were investigated in terms of seven different factors - pain, bleeding while the tampon was in place, nasal obstruction, eating difficulties, night sleep, pain during removal of the nasal packing, and bleeding after removal of packing. Results There was no statistically significant difference between the groups in terms of pain 24 hours after operation (p=0.05), while visual analog scale (VAS) scores for nasal obstruction, night sleep, eating difficulties, and pain during packing removal were lower in the nasal splint group with a statistically significant difference (p<0.05). There was no statistically significant difference between the groups in terms of postoperative bleeding (p=0.23). Significantly less bleeding occurred during removal of the packing in the nasal splint group (p<0.05). Conclusion Our study indicates that the nasal splint was more comfortable and effective in terms of causing lesser bleeding and pain during removal of packing. PMID:29392071

  12. Involvement of vascular endothelial growth factor in nasal obstruction in patients with nasal allergy

    Directory of Open Access Journals (Sweden)

    Tetsuji Yamashita

    2000-01-01

    Full Text Available It has recently been shown that vascular endothelial growth factor (VEGF enhances vascular permeability and that mast cells produce VEGF, suggesting the involvement of VEGF in allergic diseases. In the present study we quantitatively analyzed VEGF in the nasal lavage fluid of patients with nasal allergy. We performed nasal antigen challenge with Japanese cedar pollen antigen in 10 healthy adult volunteers and in 10 cedar pollen IgE-positive patients with nasal allergy. In all patients with nasal allergy, VEGF and histamine levels in the nasal lavage fluid reached a peak 30 min after antigen challenge, then returned to prechallenge values 2 h after antigen challenge. In these patients, the histamine level increased three-fold, while the VEGF level increased 10-fold. However, in all healthy adult volunteers, VEGF and histamine levels did not increase. A stronger correlation was noted between the ratio of decreased nasal cavity volume and the ratio of increased VEGF levels (R = 0.823; P < 0.001 than between the ratio of nasal cavity volume and the ratio of increased histamine levels (R = 0.660; P < 0.01. These results suggest that VEGF may contribute to the pathogenesis of nasal obstruction in the early phase of nasal allergy as a new factor involved in increasing vascular permeability.

  13. Kleben von Kunststoff mit Metall

    CERN Document Server

    Brockmann, W; Käufer, H

    1989-01-01

    Das Buch behandelt das Kleben von Kunststoffen mit Metallen in einer fur den Praktiker verstandlichen und umsetzbaren Form. Es leitet zu Klebeverfahren an, die optimale Ergebnisse hinsichtlich Qualitat, Dauerhaftigkeit und Wirtschaftlichkeit liefern.

  14. Nasal continuous positive airway pressure

    DEFF Research Database (Denmark)

    Scholze, Alexandra; Lamwers, Stephanie; Tepel, Martin

    2012-01-01

    Obstructive sleep apnoea (OSA) is linked to increased cardiovascular risk. This risk can be reduced by nasal continuous positive airway pressure (nCPAP) treatment. As OSA is associated with an increase of several vasoconstrictive factors, we investigated whether nCPAP influences the digital volume...... pulse wave. We performed digital photoplethysmography during sleep at night in 94 consecutive patients who underwent polysomnography and 29 patients treated with nCPAP. Digital volume pulse waves were obtained independently of an investigator and were quantified using an algorithm for continuous.......01; n = 94) and the arousal index (Spearman correlation, r = 0.21; p CPAP treatment, the AHI was significantly reduced from 27 ± 3 events · h(-1) to 4 ± 2 events · h(-1) (each n = 29; p

  15. Local control and intermediate-term cosmetic outcome following IMRT for nasal tumors. An update

    Energy Technology Data Exchange (ETDEWEB)

    Mukai, Yuki [University Hospital Zurich, Department of Radiation Oncology, Head Neck Cancer Center, Zurich (Switzerland); Yokohama City University Graduate School of Medicine, Department of Radiology, Yokohama (Japan); Janssen, Stefan [University Hospital Zurich, Department of Radiation Oncology, Head Neck Cancer Center, Zurich (Switzerland); Glanzmann, Christoph; Studer, Gabriela [University Hospital Zurich, Department of Radiation Oncology, Head Neck Cancer Center, Zurich (Switzerland); Cantonal Hospital Lucerne, Institute for Radiation Oncology, Lucerne (Switzerland); Holzmann, David [University Hospital Zurich, Department of Otorhinolaryngology, Head and Neck Surgery, Head Neck Cancer Center, Zurich (Switzerland)

    2017-04-15

    This study aims to evaluate local control and intermediate-term cosmetic outcome in patients with cancer of the nose treated with intensity-modulated radiotherapy (IMRT). From June 2008 to September 2015, 36 consecutive patients presenting with nasal cavity, ala of the nose, or nasal vestibule tumors were treated at the Department of Radiation Oncology, University Hospital Zurich either postoperatively (n = 14; 3/14 with nasal ablation) or with definitive IMRT (n = 22). Of these 36 patients, 8 presented with recurrent disease after surgery only and 1/36 with N1 disease. Concurrent systemic therapy was administered in 18/36 patients (50%). Nasal follow-up (FU) imaging documentation of 13 patients with preserved organ and >6 months FU offers a pre/post IMRT FU comparison. In addition, these patients' subjective evaluation of cosmesis was assessed. Mean/median FU was 41/33 months (range 5-92 months). Salvage ablation with curative intent was undergone by 3 patients with local relapse after definitive (n = 2) and postoperative (n = 1) IMRT. The 3-year local control, ultimate local control, and overall survival rates were 90, 97, and 90 %, respectively. Subjective and objective cosmetic outcome after IMRT is very satisfying so far. IMRT for nasal tumors was found to be effective and well tolerated. Intermediate-term cosmetic results are good. Radical surgical procedures may be saved for curative salvage treatment. (orig.) [German] Evaluation der Lokalkontrolle und des mittelfristigen kosmetischen Resultats nach intensitaetsmodulierter Radiotherapie (IMRT) von Patienten mit Nasentumoren. Von Juni 2008 bis September 2015 wurden an der Klinik fuer RadioOnkologie am UniversitaetsSpital Zuerich 36 konsekutive Patienten mit Tumoren der Nasenhoehle, der Nasenfluegel oder des Vestibulum nasi postoperativ (n = 14; 3/14 nach Nasenablation) oder definitiv IMRT-bestrahlt (n = 22). Von diesen 36 Patienten zeigten 8 ein Lokalrezidiv nach alleiniger vorangegangener Chirurgie und

  16. Spectral features of nasals in Standard Latvian

    Directory of Open Access Journals (Sweden)

    Jana Taperte

    2015-12-01

    Full Text Available In the article, the acoustic features of nasals in Standard Latvian are investigated. The aim of the study is to examine whether some of the spectral properties of nasal murmur (namely anti-formant frequency, as well as frequency and bandwidth of the first nasal formant can be considered as efficient cues for distinguishing between nasal places of articulation.Speech recordings from 10 native speakers of Standard Latvian, five male and five female, aged 19–39, without any disorders or dialectal traces in their pronunciation, were used for the analysis. Prevocalic nasals [m; n; ɲ] were analyzed in isolated CVC syllables, where C is one of the nasals and V is one of the vowels [i(ː; e(ː; æ(ː; ɑ(ː; ɔ(ː; u(ː]. The velar [ŋ] — the allophone of the phoneme /n/ — was recorded in postvocalic position in [k]V[ŋks] structure units. 1260 items were analyzed in total.According to the results, the nasals of Standard Latvian can be distinguished by anti-formant frequencies rather efficiently, and the results generally agree with those obtained in previous research of Latvian as well as data reported for other languages. The frequencies and the bandwidths of the first nasal formant are less informative regarding nasal place of articulation and can be used only for distinguishing between [ŋ] and [m; n; ɲ]. Conducting perception tests to assess the auditory relevance of these acoustic features is necessary.

  17. Briquetting properties of sponge iron at high temperature; Das Heissbrikettierverhalten von Eisenschwamm

    Energy Technology Data Exchange (ETDEWEB)

    Naundorf, W. [TU Bergakademie Freiberg (Germany); Trommer, D. [TU Bergakademie Freiberg (Germany); Guenter, H. [Koeppern Aufbereitungstechnik GmbH und Co. KG (Germany); Kuschel, M. [TU Bergakademie Freiberg (Germany)

    1994-12-31

    In the briquetting laboratory of the TU Bergakademie Freiberg hot briquetting of sponge iron was investigated. It was found that on increasing the pressing temperature in the range of 600 C to 1000 C a sudden improvement of briquette quality occurs. Applying a pressure of p = 200 MPa and a pressing temperature of above 700 C practically all kinds of sponge iron can be densified into briquettes with a density of {>=} 5 g/cm{sup 3}. As the pressing temperature increases the thickness expansion of the briquettes decreases, turning into a shrinkage process above 600 C. As regards the effect of grain size of sponge iron on briquette quality it was found that coarser fractions of the raw material lead to more dense and harder briquetts under the same briquetting conditions. Fine material with a grain size < 6 mm deteriorates briquette quality. Further more, it has been established that there is a order of rank in the briquettability. (orig.) [Deutsch] Im Brikettierlabor der TU Bergakademie Freiberg wude das Heissbrikettierverhalten von Eisenschwaemmen untersucht. Es wurde gefunden, dass mit steigender Verpressungstemperatur der Eisenschwaemme im Bereich 600 C bis 1000 C eine sprunghafte Verbesserung der Brikettqualitaet erreicht wird. Bei Anwendung eines Pressdruckes von p = 200 MPa und einer Verpressungstemperatur oberhalb 700 C lassen sich faktisch alle Eisenschwaemme zu Briketts mit einer Rohdichte {>=} 5 g/cm{sup 3} verdichten. Mit steigender Verpressungstemperatur vermindert sich die Dickenexpansion der Briketts. Oberhalb 600 C setzt eine Schrumpfung der Briketts ein. Zum Einfluss der Koernung der Eisenschwaemme auf die Brikettqualitaet wurde festgestellt, dass sich groebere Produktfraktionen unter gleichen Brikettierbedingungen zu dichteren und festeren Briketts verpressen lassen. Feingut mit der Korngroesse < 6 mm verschlechtert die Qualitaet der Briketts. Es konnte weiter festgestellt werden, dass eine Rangfolge im Brikettiercharakter der Eisenschwaemme besteht

  18. Omalizumab a new prospective: a nasal polyposis.

    Science.gov (United States)

    Cavaliere, C; Begvarfaj, E; Frati, F; Masieri, S

    2018-01-01

    Omalizumab, a monoclonal antibody against IgE, may be effective on nasal polyps, but its use is not currently authorized to treat that disease. We report the cases of three patients who were given omalizumab for asthma after undergoing nasal surgical polypectomy. Although such procedure is frequently followed by polyp recurrence, none of the three patients developed this complication, and in one subject the regression of initial polyp return was registered after starting omalizumab. Our data support the hypothesis that omalizumab may be useful to treat nasal polyposis.

  19. Angiomatous nasal polyp: Clinical diagnostic dilemma

    Directory of Open Access Journals (Sweden)

    Sunder Goyal

    2015-03-01

    Full Text Available Angiomatous polyp (Angiectatic nasal polyps is rare and its incidence is 4-5% of all nasal polyps. As it occurs with variable clinical features and there is no confirmatory preoperative investigation, clinical diagnosis can be a dilemma. Clinical picture of angiofibroma, simple antrochoanal polyp and inverted papilloma may resemble with each other. As polyps invade surrounding bone, these should be distinguished from a malignant mass. We present an interesting case of an infarcted angiectatic nasal polyp with extensive surrounding bony destruction. Correct preoperative radiological diagnosis is important to avoid unnecessary extensive surgery. Histopathological evaluation of polyps is mandatory since they require different treatment due to difference in the prognosis.

  20. Models for settlement prediction of structures in opencast dumps; Modelle zur Setzungsprognose von Bauwerken auf Tagebaukippen

    Energy Technology Data Exchange (ETDEWEB)

    Birle, E.; Vogt, S. [Technische Univ. Muenchen (Germany). Zentrum Geotechnik

    2016-05-01

    Strassendammes, koennen die in den Kippenuntergrund eingetragenen Zusatzspannungen zu einer Erhoehung der Verformungsgeschwindigkeiten gegenueber den Kippeneigensetzungen fuehren. Einfache ein-dimensionale phaenomenologische Kriechmodelle sind in diesem Fall nicht in der Lage, das damit verbundene Verformungsverhalten der Kippenboeden zu beschreiben, da die Abhaengigkeit der Verformungsrate vom eingepraegten Spannungszustand nicht abgebildet wird. Stattdessen koennen, wie im Beitrag erlaeutert wird, visko-elastoplastische Stoffmodelle herangezogen werden, mit denen die sich einstellenden Kippensetzungen zutreffend beschrieben werden koennen. Voraussetzung zur Anwendung der Stoffmodelle ist aber eine Kalibrierung der Stoffmodellparameter fuer die betrachtete Kippenrandbedingung anhand von Setzungsmessungen.

  1. Nasal mass removal in the koala (Phascolarctos cinereus).

    Science.gov (United States)

    Bercier, Marjorie; Wynne, Janna; Klause, Stephen; Stadler, Cynthia K; Gorow, April; Pye, Geoffrey W

    2012-12-01

    Nasal masses in the koala (Phascolarctos cinereus) are not uncommon and can be challenging to diagnose and treat. Differential diagnoses for nasal masses in the koala are cryptococcal granulomas, nasal polyps, nasal adenocarcinoma, and osteochondromatosis. This report describes successful surgical approaches for two adult koalas with nasal masses and includes photodocumentation and description of the anatomy of the koala nasal passages from the postmortem transverse sectioning of a normal koala head. Surgical removal of the nasal masses in these koalas resulted in a rapid resolution of clinical signs.

  2. Determination of specific concentration variations of atmospheric trace elements in precipitation as a method for the estimation of spatial deposition into the soil by use of statistical methods; Ermittlung spezifischer Konzentrationsverlaeufe atmosphaerischer Spurenbestandteile in Niederschlaegen als Methode zur Abschaetzung des flaechenhaften Stoffeintrags in den Boden unter Anwendung statistischer Methoden

    Energy Technology Data Exchange (ETDEWEB)

    Busch, U. [Dortmund Univ. (Germany). Fachbereich Statistik; Vautz, W. [Institut fuer Spektrochemie und Angewandte Spektroskopie (ISAS), Dortmund (Germany); Klockow, D. [Institut fuer Spektrochemie und Angewandte Spektroskopie (ISAS), Dortmund (Germany); Urfer, W. [Dortmund Univ. (Germany). Fachbereich Statistik

    1995-08-01

    Witterungsdaten - und die genauere Abschaetzung der raeumlichen Verteilung von Stoffkonzentrationen in Niederschlaegen. Schliesslich wird ein Interpolationsverfahren fuer Depositionsdaten vorgeschlagen, das die geschaetzten Parameter dieser Modelle und Witterungsdaten als zusaetzliche Information verwendet. Seine Anwendung auf die Daten von 1992 ergibt erste Depositionskarten. Der Bericht schliesst mit einigen Vorschlaegen, wie die Ergebnisse aus diesem Projekt in zukuenftigen Untersuchungen zur trockenen Deposition verwendet werden koennten. (orig.)

  3. Effect of Local Nasal Immunotherapy on Nasal Blockage in Pollen-Induced Allergic Rhinitis of Guinea Pigs

    Directory of Open Access Journals (Sweden)

    Takeshi Nabe

    2008-01-01

    Conclusions: Local nasal immunotherapy may be clinically useful for allergic nasal blockage associated with nasal hyperresponsiveness. The mechanisms responsible for this effectiveness might not be related to IgE production. Additionally, the effectiveness for nasal tissue was dissociated from that seen for the ocular tissue.

  4. Perceiving nasal patency through mucosal cooling rather than air temperature or nasal resistance.

    Directory of Open Access Journals (Sweden)

    Kai Zhao

    Full Text Available Adequate perception of nasal airflow (i.e., nasal patency is an important consideration for patients with nasal sinus diseases. The perception of a lack of nasal patency becomes the primary symptom that drives these patients to seek medical treatment. However, clinical assessment of nasal patency remains a challenge because we lack objective measurements that correlate well with what patients perceive. The current study examined factors that may influence perceived patency, including air temperature, humidity, mucosal cooling, nasal resistance, and trigeminal sensitivity. Forty-four healthy subjects rated nasal patency while sampling air from three facial exposure boxes that were ventilated with untreated room air, cold air, and dry air, respectively. In all conditions, air temperature and relative humidity inside each box were recorded with sensors connected to a computer. Nasal resistance and minimum airway cross-sectional area (MCA were measured using rhinomanometry and acoustic rhinometry, respectively. General trigeminal sensitivity was assessed through lateralization thresholds to butanol. No significant correlation was found between perceived patency and nasal resistance or MCA. In contrast, air temperature, humidity, and butanol threshold combined significantly contributed to the ratings of patency, with mucosal cooling (heat loss being the most heavily weighted predictor. Air humidity significantly influences perceived patency, suggesting that mucosal cooling rather than air temperature alone provides the trigeminal sensation that results in perception of patency. The dynamic cooling between the airstream and the mucosal wall may be quantified experimentally or computationally and could potentially lead to a new clinical evaluation tool.

  5. Unilateral nasal pain with migraine features.

    Science.gov (United States)

    Alvarez, Mónica; Montojo, Teresa; de la Casa, Beatriz; Vela, Lydia; Pareja, Juan A

    2013-09-01

    Migraine attacks exclusively felt in the face are very rare, the pain involving the territories supplied by the second and third branches of the trigeminal nerve. Two patients suffering from heminasal pain attacks accompanied with typical migrainous features and responsive to oral or intranasal triptans - but not to intranasal lidocaine or oxymetazoline. In one patient, the attacks could be precipitated upon slight touching on the tip of the nose, in the other attacks were preceded by the nasal sensation typically heralding sneezing. Migraine pain mostly develops within the innervation territory of the first branch of the trigeminal nerve, which includes the nose. Therefore, episodes of unilateral nasal pain with migrainous features could be considered a migraine with unusual topography (nasal migraine). Painful nasal attacks occasionally preceded by stimulation of trigeminal afferents in the nose, could be conceived of as migraine-tic syndrome.

  6. Periapical Infection Masquerading as a Nasal Pustule

    African Journals Online (AJOL)

    Keywords: Endodontic treatment, Maxillary central incisor, Nasal pustule, Periapical infection,. Root length ... back under copious irrigation. Non‑setting calcium ... of working length. Figure 4: Obturated root canal of maxillary right central incisor ...

  7. Nasal Chondromesenchymal Hamartoma in a Child

    International Nuclear Information System (INIS)

    Finitsis, Stefanos; Giavroglou, Constantinos; Potsi, Stamatia; Constantinidis, Ioannis; Mpaltatzidis, Angelos; Rachovitsas, Dimitrios; Tzioufa, Valentini

    2009-01-01

    Nasal chondromesenchymal hamartoma (NCMH) is a benign tumor that was described in 1998. The occurrence of this lesion in the nasal cavity of infants and children is especially rare, with only 21 cases reported in the international literature. We report a 12-month-old boy with respiratory distress due to nasal obstruction. Computed tomographic scan and magnetic resonance imaging examination demonstrated a soft-tissue mass obstructing the left nasal cavity. Digital subtraction angiography and preoperative superselective embolization with microparticles were also performed. The tumor was completely resected surgically. Histopathology and immunohistochemical analyses of the tumor disclosed a NCMH. The imaging characteristics of the tumor are described and the radiology literature is reviewed.

  8. Human factor in Staphylococcus aureus nasal carriage

    NARCIS (Netherlands)

    J.L. Nouwen (Jan); H.A.M. Boelens (Hélène); A.F. van Belkum (Alex); H.A. Verbrugh (Henri)

    2004-01-01

    textabstractPersistent nasal carriers and noncarriers of Staphylococcus aureus were inoculated with a mixture of different S. aureus strains. The majority of noncarriers and nearly all persistent carriers returned to their original carrier state after artificial inoculation. Furthermore, the

  9. Nasal manifestations in chromium industry workers.

    Science.gov (United States)

    Aiyer, R G; Kumar, Gaurav

    2003-04-01

    People working in mines, plating factories, cement industries are mainly exposed to chrome substances, IIexavalent chromium has been implicated for its toxic effect on the nasal mucosa. Hereby we present a rare study of 28 patients who attended out patient department of Otorhinolaryngology at SSG Hospital, Baroda from a nearby chromium industry. This study aims to present various nasal manifestations of toxic effects of prolonged chromium exposure.

  10. Richard von Volkmann

    Science.gov (United States)

    Willy, Christian; Schneider, Peter; Engelhardt, Michael; Hargens, Alan R.

    2008-01-01

    Richard von Volkmann (1830–1889), one of the most important surgeons of the 19th century, is regarded as one of the fathers of orthopaedic surgery. He was a contemporary of Langenbeck, Esmarch, Lister, Billroth, Kocher, and Trendelenburg. He was head of the Department of Surgery at the University of Halle, Germany (1867–1889). His popularity attracted doctors and patients from all over the world. He was the lead physician for the German military during two wars. From this experience, he compared the mortality of civilian and war injuries and investigated the general poor hygienic conditions in civilian hospitals. This led him to introduce the “antiseptic technique” to Germany that was developed by Lister. His powers of observation and creativity led him to findings and achievements that to this day bear his name: Volkmann’s contracture and the Hueter-Volkmann law. Additionally, he was a gifted writer; he published not only scientific literature but also books of children’s fairy tales and poems under the pen name of Richard Leander, assuring him a permanent place in the world of literature as well as orthopaedics. PMID:18196438

  11. CT findings of malignant nasal cavity tumors

    International Nuclear Information System (INIS)

    Ku, Young Mi; Chun, Kyung Ah; Choi, Kyu Ho; Yu, Won Jong; Kim, Young Joo; Kim, Sung Hoon; Park, Seog Hee; Shinn, Kyung Sub

    1997-01-01

    To evaluate the CT findings of malignant nasal cavity tumors. Retrospective analysis was performed on 20 patients with pathologically-proven malignant nasal cavity tumors. Using CT, we analysed their location, extent of bone destruction and of involvement of adjacent structures, and enhancing pattern. A total of 20 cases included nine squamous cell carcinomas, three olfactory neuroblastomas, three lymphomas, two polymorphic reticulosis, one adenoid cystic carcinoma, one undifferentiated carcinoma and one metastasis from renal cell carcinoma. All cases except one adenoid cystic carcinoma and one squamous cell carcinoma revealed bone destruction or erosion. Aggressive bone destruction and irregular enhancement were seen in eight cases of squamous cell carcinoma, seven cases of which showed involvement of the adjacent paranasal sinuses, nasopharynx, and orbit. Olfactory neuroblastomas were centered in the superior nasal cavity and the adjacent ethmoid sinus, and erosion or destruction of the cribriform plate had occurred. Lymphomas showed bilateral involvement, with uniform contrast enhancement. Polymorphic reticuloses showed perforation or erosion of the nasal septum, with bilateral involvement of the nasal cavity. The location, presence of bone destruction, involvement of adjacent structures, and enhancement pattern of tumor on CT can be helpful for the differential diagnosis of malignant nasal cavity tumors

  12. Eosinophilic Angiocentric Fibrosis of the Nasal Septum

    Directory of Open Access Journals (Sweden)

    Yunchuan Li

    2013-01-01

    Full Text Available Background. Eosinophilic angiocentric fibrosis (EAF is a rare benign condition of unknown aetiology that causes stenosis of the upper respiratory tract. It is most commonly found at the nasal septum and sinus mucosa causing mucosal thickening and nasal obstructive symptoms. The diagnosis is mainly based on characteristic histologic findings. Case Report. A 27-year-old young woman presented with a slow growing mass at her anterior nasal septum for over eight years. She complained of persistent nasal obstruction, epistaxis, sometimes diffused facial pain, and chronic headache. 3 years ago, the tumor was partially resected for ventilation and a nasal septum perforation was left. Imaging findings indicated soft-tissue thickening of the anterior part of septum and adjacent lateral nasal walls. Pathological examination showed numerous inflammatory cells infiltrates containing eosinophils, fibroinflammatory lesion with a whorled appearance fibrosis which typically surrounded vessels. A diagnosis of eosinophilic angiocentric fibrosis was made. All laboratory tests were unremarkable. Skin prick test was positive. The tumor-like lesion was totally resected. Conclusions. EAF is a rare benign and progressive disorder causing destruction. Combined with radiological imaging of EAF historical findings contribute to the diagnosis. It is important to prevent tumor from recurrence by total resection of the lesion.

  13. NASALIZATION IN BRAZILIAN PORTUGUESE: AN AUTOSEGMENTAL (REVIEW

    Directory of Open Access Journals (Sweden)

    Consuelo de Paiva Godinho COSTA

    2015-06-01

    Full Text Available We propose to make a brief review on nasalization phenomena studies in Portuguese, aiming the phonological process of nasal harmonization that occurs in the variety of Brazilian Portuguese spoken in Vitória da Conquista-BA and region, a phenomenon hitherto not described for any Portuguese dialect. To do so, we consider as fundamental, D’Angelis (2002 analysis, which incorporates relevant concepts presented by Trubetzkoy, from the Prague School, and some points of Camara Jr. propose. We also propose to update the discussion with the approaches along the lines of auto segmental phonology, incorporating some insights of Piggott (1992, discussing with other analyzes for nasalization phenomena in other languages, especially Guarani (language of Tupi-Guarani Linguistic Family, as proposed by Costa (2010, which deals with the phonological processes involving nasality and nasal harmony in Brazilian indigenous languages , in order to verify if the researches on nasality phenomena in other languages can shed some light on the processes that occur in Portuguese.

  14. Aggregation und Management von Metadaten im Kontext von Europeana

    Directory of Open Access Journals (Sweden)

    Gerda Koch

    2017-09-01

    Full Text Available Mit dem In-Beziehung-Setzen und Verlinken von Daten im Internet wird der Weg zur Umsetzung des semantischen Webs geebnet. Erst die semantische Verbindung von heterogenen Datenbeständen ermöglicht übergreifende Suchvorgänge und späteres „Machine Learning“. Im Artikel werden die Aktivitäten der Europäischen Digitalen Bibliothek im Bereich des Metadatenmanagements und der semantischen Verlinkung von Daten skizziert. Dabei wird einerseits ein kurzer Überblick zu aktuellen Forschungsschwerpunkten und Umsetzungsstrategien gegeben, und darüber hinaus werden einzelne Projekte und maßgeschneiderte Serviceangebote für naturhistorische Daten, regionale Kultureinrichtungen und Audiosammlungen beschrieben.

  15. Regional deposition of mometasone furoate nasal spray suspension in humans.

    Science.gov (United States)

    Shah, Samir A; Berger, Robert L; McDermott, John; Gupta, Pranav; Monteith, David; Connor, Alyson; Lin, Wu

    2015-01-01

    Nasal deposition studies can demonstrate whether nasal sprays treating allergic rhinitis and polyposis reach the ciliated posterior nasal cavity, where turbinate inflammation and other pathology occurs. However, quantifying nasal deposition is challenging, because in vitro tests do not correlate to human nasal deposition; gamma scintigraphy studies are thus used. For valid data, the radiolabel must distribute, as the drug, into different-sized droplets, remain associated with the drug in the formulation after administration, and not alter its deposition. Some nasal deposition studies have demonstrated this using homogenous solutions. However, most commercial nasal sprays are heterogeneous suspensions. Using mometasone furoate nasal suspension (MFS), we developed a technique to validate radiolabel deposition as a surrogate for nasal cavity drug deposition and characterized regional deposition and nasal clearance in humans. Mometasone furoate (MF) formulation was spiked with diethylene triamine pentacaetic acid. Both unlabeled and radiolabeled formulations (n = 3) were sprayed into a regionally divided nasal cast. Drug deposition was quantified by high pressure liquid chromatography within each region; radiolabel deposition was determined by gamma camera. Healthy subjects (n = 12) were dosed and imaged for six hours. Scintigraphic images were coregistered with magnetic resonance imaging scans to quantify anterior and posterior nasal cavity deposition and mucociliary clearance. The ratio of radiolabel to unlabeled drug was 1.05 in the nasal cast and regionally appeared to match, indicating that in vivo radiolabel deposition could represent drug deposition. In humans, MFS delivered 86% (9.2) of metered dose to the nasal cavity, approximately 60% (9.1) of metered dose to the posterior nasal cavity. After 15 minutes, mucociliary clearance removed 59% of the initial radiolabel in the nasal cavity, consistent with clearance rates from the ciliated posterior surface. MFS

  16. Low lymphatic vessel density associates with chronic rhinosinusitis with nasal polyps.

    Science.gov (United States)

    Luukkainen, A; Seppälä, M; Renkonen, J; Renkonen, R; Hagstrő M, J; Huhtala, H; Rautiainen, M; Myller, J; Paavonen, T; Ranta, A; Torkkeli, T; Toppila-Salmi, S

    2017-06-01

    Chronic rhinosinusitis with and without nasal polyps (CRSwNP and CRSsNP) and antrochoanal polyps (ACP) are different upper airway inflammation phenotypes with different pathomechanisms. In order to understand the development of tissue edema, the present study aimed to evaluate lymphatic vessel density in CRSsNP, CRSwNP and ACP. 120 retrospective nasal and maxillary sinus specimens were stained immunohistochemically with a von Willebrand factor polyclonal antibody recognizing vascular and lymphatic endothelium, and with a podoplanin monoclonal antibody recognizing lymphatic endothelium. Vessels were studied by microscopy in a blinded fashion, and the vessel density and the relative density of lymphatic vessels were calculated. Patient characteristic factors and follow-up data of in average 9 years were collected from patient records. In the nasal cavity, the low absolute and relative density of vessels and of lymphatic vessels was associated with CRSwNP and ACP tissues compared to control inferior turbinate. This was observed also in the inflammatory hotspot area. In the maxillary sinus, lower absolute and relative density of lymphatic vessels associated with the CRSwNP phenotype. High lymphatic vessel density in polyp tissue associated with the need for revision CRS-surgery. As a conclusion, low density of lymphatic vessels distinguished patients with CRSwNP not only in the hotspot area of polyp tissue, but also in maxillary sinus mucosa. Yet, higher lymphatic vessel density seems to associate with polyp recurrence. Further studies are still needed to explore if formation of nasal polyps could be diminished by intranasal therapeutics affecting lymphangiogenesis.

  17. Non-destructive testing of concrete structures with the impact-echo method; Zerstoerungsfreie Pruefung von Betonbauteilen mit dem Impact-Echo-Verfahren

    Energy Technology Data Exchange (ETDEWEB)

    Algernon, Daniel; Feistkorn, Sascha; Scherrer, Michael [SVTI Schweizerischer Verein fuer technische Inspektionen, Wallisellen (Switzerland). Nuklearinspektorat

    2016-05-01

    The impact-echo method is based on the use of elastic waves. It was developed in the 1980 for the testing of concrete structures and is currently widespread. Main application areas are the component and coating thickness measurement and detection of delaminations, voids and other defects. Specifically, the method is also used to check the injection faults of clamping channels. Another application is the determination of mechanical material parameters such as the modulus of elasticity. Since the original development of the method has undergone several enhancements. The conversion of a single-point measurement method towards a area component testing, the use by the optimized measurement data acquisition and evaluation enlarged and delivered an important prerequisite for increasing the efficiency. The use of air-coupled sensors not only increases the measurement speed but also provides advantages in rough component surfaces. The imaging analysis in conjunction with signal processing algorithms simplifies the interpretation and allows statistical evaluation. [German] Das Impact-Echo-Verfahren beruht auf der Nutzung elastischer Wellen. Es wurde in den 1980er Jahren fuer die Pruefung von Stahlbetonbauteilen entwickelt und ist derzeit weit verbreitet. Haupteinsatzgebiete sind die Bauteil- und Schichtdickenmessung sowie die Detektion von Delaminationen, Hohl- und anderen Fehlstellen. Insbesondere wird das Verfahren auch zur Pruefung des Verpresszustandes von Spannkanaelen herangezogen. Eine weitere Anwendung ist die Bestimmung mechanischer Materialparameter wie dem Elastizitaetsmodul. Seit der urspruenglichen Entwicklung hat das Verfahren verschiedene Weiterentwicklungen erfahren. Die Ueberfuehrung von einem Einzelpunktmessverfahren hin zu einer flaechigen Bauteilpruefung hat die Einsatzmoeglichkeiten durch die optimierte Messdatenaufnahme und -auswertung vergroessert und eine wichtige Voraussetzung zur Erhoehung der Leistungsfaehigkeit geliefert. Der Einsatz

  18. Nasal obstruction and smell impairment in nasal polyp disease: correlation between objective and subjective parameters

    NARCIS (Netherlands)

    Hox, V.; Bobic, S.; Callebaux, I.; Jorissen, M.; Hellings, P. W.

    2010-01-01

    Chronic rhinosinusitis with nasal polyposis (NP) represents an invalidating disorder that causes mainly nasal blockage and loss of smell. The aim of this study is to investigate correlations between individual subjective and objective parameters of stable NP disease. 65 NP patients scored their

  19. Nasal endotracheal intubation in a premature infant with a nasal encephalocele.

    Science.gov (United States)

    Bannister, C M; Kashab, M; Dagestani, H; Placzek, M

    1993-01-01

    After a difficult nasal intubation a premature infant leaked cerebrospinal fluid (CSF) from one nostril. After developing bacterial meningitis, the baby was referred for neurosurgical management of the CSF fistula. Transaxial computed tomograms demonstrated a nasal encephalocele, but coronal scans were needed to show the defect in the cribriform plate. Images PMID:8346963

  20. John von Neumann selected letters

    CERN Document Server

    2005-01-01

    John von Neuman was perhaps the most influential mathematician of the twentieth century, especially if his broad influence outside mathematics is included. Not only did he contribute to almost all branches of mathematics and created new fields, but he also changed post-World War II history with his work on the design of computers and with being a sought-after technical advisor to many figures in the U.S. military-political establishment in the 1940s and 1950s. The present volume is the first substantial collection of (previously mainly unpublished) letters written by von Neumann to colleagues, friends, government officials, and others. The letters give us a glimpse of the thinking of John von Neumann about mathematics, physics, computer science, science management, education, consulting, politics, and war. Readers of quite diverse backgrounds will find much of interest in this fascinating first-hand look at one of the towering figures of twentieth century science.

  1. Transobturatorielle Schlingensysteme (Monarc(R, Serasis TO(R: Ein erster Erfahrungsbericht von 150 Fällen

    Directory of Open Access Journals (Sweden)

    Fischer A

    2005-01-01

    Full Text Available Fragestellung: Überkorrektur mit ihren Begleiterscheinungen Obstruktion und Drangsymptomatik, retropubisches Hämatom und Blasenperforation sind die Hauptkomplikationen der mitturethralen spannungsfreien Bänder und kommen selbst nach fast 2000 Anwendungen immer wieder einmal vor. Zum Teil ist dies abhängig von Voroperationen, der Indikationsstellung, zum Teil auch von der Bandspannung, möglicherweise aber auch vom Weg des Bandes um die Urethra. Die Anwendung eines transobturatoriellen Systems soll nun zeigen, wo die Unterschiede bei dieser unterschiedlichen Technik und Bandverlauf liegen. Methode: 100 transobturatorielle Schlingen vom Typ Monarc(R (AMS, Berlin und 50 transobturatorielle Schlingen Serasis TO(R (Serag-Wiessner, Naila wurden in der Zeit von Anfang Februar bis Mitte Mai 2003 in unserer Klinik eingelegt. Perinealsonographie und Urodynamik inkl. Pad-Test sowie eine körperliche Untersuchung und ein Patientinnenfragebogen zur QoL wurden bei allen Frauen präoperativ und in der Folge nach 6 Wochen, 3 und 6 Monaten postoperativ durchgeführt. Ein Valsalva Leak Point Pressure wurde prä- und postoperativ nach 6 Monaten ermittelt. Der Eingriff erfolgt in Kurznarkose. Ergebnisse: Bei beiden Systemen zeigte sich eine durchschnittliche OP-Zeit von 8–10 Minuten und eine fehlende Hämatombildung sowie eine Blasenläsion bei der Monarc-Anwendung. Sonst trat bei beiden Systemen keine intraoperative Komplikation bei einem durchschnittlichen Blutverlust von ca. 20 ml auf. Perioperativ zeigte sich bei 12 % der mit Monarc behandelten Patienten eine Bakteriurie in den ersten 48 Stunden postoperativ, bei den Serasis-Patientinnen in 4 % der Fälle. Drei Monarc-Bänder und ein Serasis-Band mußten im Zusammenhang mit Drang durchtrennt werden. Fehlende postoperative Wundschmerzen und bis dato praktisch keine Zeichen einer Überkorrektur oder pathologischen Restharnbildung lassen den Unterschied zu den etablierten Inkontinenzoperationen deutlich

  2. Automatisierung von HiL Tests

    OpenAIRE

    Asbach, Lennart; Ebrecht, Lars

    2010-01-01

    Automatisierung von HiL Tests. Darstellung und Bewertung einer praktischen Umsetzung. Das Poster zeigt die Motivation, die Durchführung, einen aktuellen Stand und einen Ausblick der Testautomatisierung im Bahnlabor RailSiTe. Als Beispiel dient der Konformitätstest von ETCS-Onboard Zugrechnern, um die Einführung von ETCS zu unterstützen.

  3. Clinical aspects of patients with nasal polyposis

    Directory of Open Access Journals (Sweden)

    Crespo, Cassio Caldini

    2009-09-01

    Full Text Available Introduction: The nasal Polyposis is a non-neoplastic chronic inflammatory process of the nasal mucosa. It causes a large impact to the patients' life quality. Objective: To analyze the characteristics of patients with polyposis in the Brazilian population. Method: 50 records of patients followed up in a tertiary hospital and submitted to surgical treatment of nasal polyposis were reviewed. The following variables were analyzed: age, sex, smoking, presence of asthma, presence of AAS intolerance and also the clinical manifestations: anterior and posterior rhinorrhea, nasal obstruction, hyposmia, sneezing and pruritus. The tomographic evaluation system applied was that of Lund-McKay. For statistical analysis we applied the chi-square test with p<0.05. Results: Out of 50 patients evaluated, 28 were male and 22 were female. The mean age range was of 40.8 years. The main clinical manifestation was nasal obstruction in 100% of the patients. In the tomographic evaluation, according to the Lund-McKay system, the average scoring was of 10.9. Discussion: No statistically significant difference was obtained in the patients' general symptoms compared to the patients with asthma or AAS intolerance. The difference in the Lund-McKay score was statistically significant in the populations studied. The symptoms were similar to the frequency of symptoms of other works. Conclusion: We concluded that the main complaint of the patients with nasal polyposis is nasal obstruction, the most affected age is of about 40 years old, without preference of sex. The severity of tomographic findings is higher in patients with asthma and AAS intolerance.

  4. Homopteren von Java, gesammelt von Herrn Edw. Jacobson

    NARCIS (Netherlands)

    Melichar, L.

    1914-01-01

    Herr Edw. Jacobson hat auf Java in den Jahren 1908— 1910 Homopteren gesammelt und mir die Bearbeitung des gesammelten Materiales übertragen. Die Jacobson’sche Ausbeute ist insoferne bemerkenswert, als dieselbe viele Mikrohomopteren enthält, welche von nichtfachkundigen Sammlern gewöhnlich nicht

  5. Nasal obstruction and sleep-disordered breathing: the effect of supine body position on nasal measurements in snorers.

    Science.gov (United States)

    Virkkula, Paula; Maasilta, Paula; Hytönen, Maija; Salmi, Tapani; Malmberg, Henrik

    2003-06-01

    Nasal obstruction is considered to be a potential etiological factor in sleep-disordered breathing. However, a significant correlation between nasal measurements and obstructive sleep apnea has not been demonstrated so far. The aim of this study was to investigate the relationships between nasal resistance, nasal volumes and selected sleep parameters using nasal measurements performed in both seated and supine positions. We also investigated whether snoring patients in our clinical sample showed increased positional or decongestive nasal mucosal changes. Forty-one snoring men on a waiting list for correction of nasal obstruction underwent polysomnography, anterior rhinomanometry and acoustic rhinometry. Nineteen non-snoring control subjects were also recruited. Nasal measurements were performed in a seated position, after lying down in a supine position and, after decongestion of nasal mucosa, in a seated position again. In the overall patient group, nasal volume at a distance 2-4 cm from the nares in the supine position correlated inversely with apnea-hypopnea index (AHI) (r = -0.32, p patients, total nasal resistance measured in a supine position correlated with AHI (r = 0.50, p position and sleep parameters. Postural or decongestive changes in nasal measurements were not increased in snoring patients compared with control subjects. The relationship found between nasal measurements and sleep parameters suggests that nasal obstruction does augment airway collapse.

  6. Preparation of MMC structures consisting of carbonfibre/aluminium prepregs by using the high velocity flame spraying; Herstellen von Halbzeugen aus kohlenstoffaserverstaerkten Aluminiumprepregs mit dem Hochgeschwindigkeitsflammspritzen

    Energy Technology Data Exchange (ETDEWEB)

    Wielage, B.; Rahm, J. [Lehrstuhl fuer Verbundwerkstoffe, TU Chemnitz-Zwickau, Chemnitz (Germany)

    1994-12-01

    The application of the thermal spraying process is a new way to produce carbon fibre reinforced Al-Matrix composites. Spreaded fibre rovings are enveloped in the matrix material with high velocity flame spraying. The advantage of the thermal spraying process is based in the low times for contacting between carbon fibres and liquid matrix material. Chemical reactions on the interface fibre/matrix, which are caused the decreasing of the fibre tensile strange, can be excluded. The thermal sprayed prepregs are compressed to MMC by hot pressing process. This longfibre reinforced composites are used to increase for instance casted components of motors. The aim of this research is the estimation of possibility to applicate the high velocity flame process for prepreg manufacturing. (orig.) [Deutsch] Die Anwendung des thermischen Spritzens zur Herstellung C/langfaserverstaerkter Al-Matrix Verbundwerkstoffe mittels Prepregtechnik beschreitet einen neuartigen Verfahrensweg. Zu Fasergelegen aufgespreizte Rovings werden durch Flamm- oder Hochgeschwindigkeitsflammspritzen mit dem Matrixmetall eingehuellt. Der Vorteil des thermischen Spritzens liegt in den geringen Kontaktzeiten der C-Fasern mit dem schmelzfluessigen Matrixmetall. Chemische Reaktionen zwischen Fasern und der Matrix, die zur Karbidbildung und Reduzierung der Verbundfestigkeit fuehren, koennen auch beim Verwenden von C-Fasern ohne Barriereschicht weitgehend ausgeschlossen werden. Die so hergestellten Prepregs koennen z.B. durch Heisspressen zu MMC kompaktiert werden, und als Halbzeuge (Inserts) Gussbauteile in hochbelasteten Bereichen partiell verstaerken. Die im Rahmen der Veroeffentlichung dargestellten Untersuchungen haben die kritische Beurteilung der Ergebnisse des HVOF-Spritzverfahrens zur Herstellung von C/Faser/Aluminiumprepregs zum Ziel. (orig.)

  7. Continuous and recurrent testing of acoustic emission sensors; Kontinuierliche und wiederkehrende Pruefung von Schallemissionssensoren

    Energy Technology Data Exchange (ETDEWEB)

    Sause, Markus G.R.; Schmitt, Stefan; Potstada, Philipp [Augsburg Univ. (Germany). Inst. fuer Materials Resource Management, Mechanical Engineering

    2017-08-01

    Schallemissionssensoren und ihrer Ankopplung im Labor''. Dieser Beitrag diskutiert Moeglichkeiten zur kontinuierlichen Ueberwachung der Sensoren waehrend der Pruefung und praesentiert ein Anwendungsbeispiel zur teilautomatisierten wiederkehrenden Pruefung von Schallemissionssensoren unter Anwendung der Richtlinie SE 02. Hierzu wurde ein Teststand fuer die Zufuehrung der zu pruefenden Sensoren konstruiert und die Signalaufzeichnung und Datenreduktion in entsprechenden frei verfuegbaren Softwareprogrammen umgesetzt. Anhand ausgewaehlter Fallbeispiele wird die Funktionsweise demonstriert.

  8. Properties of von Neumann entropy

    Indian Academy of Sciences (India)

    disentangled) as seen by moving observers, is used to investigate the properties of von Neumann entropy, as a measure of spin–momentum entanglement. To do so, we partition the total Hilbert space into momentum and spin subspaces so that the ...

  9. von Hippel-Lindau disease

    DEFF Research Database (Denmark)

    Binderup, Marie Louise Mølgaard; Gimsing, Steen; Kosteljanetz, Michael

    2013-01-01

    Endolymphatic sac tumours (ELSTs) of the inner ear occur in 16% of patients with the hereditary tumor syndrome von Hippel-Lindau disease (vHL). ELSTs of all sizes can cause irreversible hearing loss which can, however, be prevented through early diagnosis and treatment. We aim to emphasize the ch...

  10. [Nasal mucosa in patients with diabetes mellitus].

    Science.gov (United States)

    Müller, Maciej; Betlejewski, Stanisław

    2003-01-01

    Diabetes mellitus is the most common endocrinologic disease all over the world. 150 million people suffer from this disease, in Poland about 2 million. The disease on the basis of the onset and pathophysiology may be divided into type I and type II. Pathophysiologic changes include diabetic microangiopathy, macroangiopathy and neuropathy. The most common presentations in head and neck are otitis externa, hypoacusis, vertigo, disequilibrium, xerostomia, dysphagia, fungal and recurrent infections. The changes in nasal mucosa are not very well known. Only few papers concerned the problem. The main complaints of patients regarding the nose are xeromycteria, hyposmia and various degree of decreased patency of the nose. Chronic atrophic rhinitis, septal perforation, ulceration of nasal mucosa, alar necrosis, symptoms of staphylococcal or fungal infection can be found during otolaryngologic examination. The treatment in this group of patients should consist of systemic therapy of diabetes mellitus and on the other hand focal therapy with the use of a solution to moisten the nasal mucosa.

  11. Nasal and oral masses in a dog.

    Science.gov (United States)

    Levy, Esther; Mylonakis, Mathios E; Saridomichelakis, Manolis N; Polizopoulou, Zoe S; Psychogios, Vassilios; Koutinas, Alexander F

    2006-03-01

    A 5-year-old, intact male, stray dog was presented in poor body condition, with pallor, muzzle deformity, multiple oozing fistulas with grass awns, bilateral sanguinopurulent nasal discharge and a fleshy friable mass occupying part of the hard palate. A friable mass occupying both nasal cavities was found on rhinoscopy. The dog had moderate nonregenerative normochromic-microcytic anemia, thrombocytopenia, hyperglobulinemia, and hypoalbuminemia. Cytologic preparations of the nasal and oral masses contained a neoplastic population of round cells with intracytoplasmic and extracellular vacuoles. Leishmania amastigotes also were observed, in the cytoplasm of macrophages and, occasionally, within neoplastic cells. A diagnosis of transmissible venereal tumor and concurrent leishmaniosis was made. Treatment with vincristine and allopurinol resulted in complete resolution of clinical signs and disappearance of the masses. The presence of amastigotes in neoplastic TVT cells may suggest an alternative mode of transmission of canine leishmaniosis where these diseases co-exist.

  12. Inflammatory Myofibroblastic Tumor of the Nasal Septum

    Directory of Open Access Journals (Sweden)

    Yuri Okumura

    2013-01-01

    Full Text Available We report an extremely rare case of inflammatory myofibroblastic tumor of the posterior edge of the nasal septum. An 11-year-old boy presented with frequent epistaxis and nasal obstruction persisting for one year. Based on the clinical presentation and imaging studies, juvenile angiofibroma was suspected, but angiography suggested the possibility of another type of tumor. Transnasal endoscopic surgery found that the tumor protruded into the nasopharynx from the posterior end of the nasal septum. Histological examination identified spindle cells with immunoreaction for vimentin, smooth muscle actin, and anaplastic lymphoma kinase (ALK, but not for desmin and cytokeratin. This is a report of inflammatory myofibroblastic tumor mimicking juvenile angiofibroma. This case suggests that angiography is helpful in the differential diagnosis of epipharyngeal tumor in adolescence.

  13. Silver nasal sprays: misleading Internet marketing.

    Science.gov (United States)

    Gaslin, Michael T; Rubin, Cory; Pribitkin, Edmund A

    2008-04-01

    Long-term use of silver-containing products is associated with a permanent bluish-gray discoloration of the skin known as argyria, but they remain widely available despite several measures by the FDA to regulate them. Several recent case reports have described the occurrence of argyria as a result of using these "natural" products. We used the five most common Internet search engines to find Web sites providing information on silver-containing nasal sprays. Of 49 Web sites analyzed, only 2 (4%) mentioned argyria as a possible complication, although 30 (61%) did caution against long-term use. Eight sites (16%) made specific claims about the health benefits of the product. All 49 sites (100%) provided direct or indirect links to buy silver-containing nasal sprays. We conclude that information about silver-containing nasal sprays on the Internet is misleading and inaccurate. Therefore, otolaryngologists should be aware of the misinformation their patients may be receiving about these products.

  14. [Friedrich Ludwig von Maydelli pildid Baltimaade ajaloost = Friedrich Ludwig von Maydells Baltische Geschichte in Bildern = Friedrich Ludwig von Maydell ́s Baltic history in images] / Ulrike Plath

    Index Scriptorium Estoniae

    Plath, Ulrike, 1972-

    2014-01-01

    Arvustus: Friedrich Ludwig von Maydelli pildid Baltimaade ajaloost = Friedrich Ludwig von Maydells Baltische Geschichte in Bildern = Friedrich Ludwig von Maydell ́s Baltic history in images. Eesti kunstimuuseum, Kadrioru kunstimuuseum. Tallinn 2013

  15. Sequential extraction of heavy metals from urban dust and street sediments. Pt. 1. Sequential extraction of heavy metals in micro samples; Sequentielle Schwermetallextraktion aus Staubniederschlaegen und Strassensedimenten. T. 1. Sequentielle Schwermetallextraktion von Mikroproben

    Energy Technology Data Exchange (ETDEWEB)

    Heiser, U.; Norra, S.; Stueben, D.; Wagner, M. von [Karlsruhe Univ. (T.H.) (Germany). Inst. fuer Petrographie und Geochemie

    1999-01-01

    For the application of sequential extraction of heavy metals from samples that can only be obtained in amounts of a few milligrams (micro samples, e.g. airborne dust fallout), the method after Zeien and Bruemmer (1989) was progressed. A down scale to 1:100 was carried out and the accuracy of this method with variable sample amounts of about 20 mg and an extraction volume of 500 {mu}l was proofed with standard soil samples. The influence of variable extraction ratios (ratio of sample amount and volume of extraction solvent) and the influence of intensive treatment of dust sampled by the Bergerhoff-method (VDI 2119/2, 1972) prior sequential extraction, was within the precision of measurement of our method. Thus, we showed that sequential extraction can be applied for the investigation of heavy metal mobilization in micro samples with variable sample amounts. A first application of our method for microsamples was carried out to investigate airborne dust fallout and street sediments at two urban sites where different heavy metal immission rates due to traffic influence occur. These investigations will be presented in part 2 (`Sequential extraxction of heavy metals from urban dust`). (orig.) [Deutsch] Fuer die Anwendung der sequentiellen Schwermetallextraktion auf Proben, die nur im Milligramm-Bereich erhalten werden koennen (Mikroproben, wie z.B. Staubniederschlaege), wurde die Methode von Zeien und Bruemmer (1989) weiterentwickelt. Der Extraktionsmassstab wurde um den Faktor 1:100 verringert und die Reproduzierbarkeit des Verfahrens mit variablen Probenmengen um 20 mg und einem Extraktionsvolumen von 500 {mu}l mit Hilfe von Standardboeden nachgewiesen. Moegliche Einfluesse variabler Extraktionsverhaeltnisse (Verhaeltnis von Probenmenge zu Extraktionsvolumen) sowie eine aufwendige Vorbehandlung von Staubproben, die nach der Bergerhoff-Methode (VDI 2119/2, 1972) gesammelt wurden, lagen bei diesen Untersuchungen weitgehend im Variationsbereich des Verfahrens. Die

  16. Nasal budesonide offers superior symptom relief in perennial allergic rhinitis in comparison to nasal azelastine.

    Science.gov (United States)

    Stern, M A; Wade, A G; Ridout, S M; Cambell, L M

    1998-10-01

    Allergic rhinitis is usually treated with oral antihistamines or nasal steroids. Topically active nasal antihistamine is a new treatment modality for allergic rhinitis. The efficacy in comparison to well established topical treatment alternatives is not fully known. To compare the efficacy of intranasally administered azelastine to budesonide, at their respectively recommended dosage, on the symptoms of perennial rhinitis patients. A placebo-controlled, randomized, parallel group study was conducted to compare the efficacy and tolerability of intranasal budesonide aqueous suspension (256 microg once daily) with azelastine hydrochloride nasal spray (280 microg twice daily (560 microg/day)) and with placebo in the treatment of perennial allergic rhinitis. The 195 patients (with at least a 2-year history of perennial allergic rhinitis) recorded individual nasal symptom scores, the degree of symptom control achieved and any adverse events experienced over a 2-week baseline period and a 6-week treatment period. Following treatment, the reductions in mean combined and individual nasal symptom scores from baseline values were significantly greater in the budesonide group compared with the placebo group (P < .0001 for all variables except runny nose P = .01). In patients treated with budesonide, there were also significantly larger reductions from baseline values in combined nasal symptom scores (P < .01) and in scores for all individual nasal symptoms (P < or = .05) compared with those treated with azelastine. The reductions from baseline in both combined and individual nasal symptom scores did not differ between azelastine and placebo. The study medications were well tolerated, producing no unexpected or serious treatment-related adverse events. A once-daily dose of 256 microg of intranasal budesonide aqueous suspension is significantly more effective at relieving the symptoms of perennial allergic rhinitis compared with a twice daily dose of 280 microg of azelastine

  17. Nasal Carriage of 200 Patients with Nasal Bone Fracture in Korea

    Directory of Open Access Journals (Sweden)

    Jun Wook Lee

    2013-09-01

    Full Text Available BackgroundPathogens in the nasal cavity during nasal surgery could lead to a systemic infectious condition, such as bacteremia, nosocomial infection, or toxic shock syndrome. However, there is no research about the prevalence of nasal carriage in patients with nasal bone fracture.MethodsThis was a prospective, double-blind, randomized study about the rate of nasal carriage in 200 patients with nasal bone fracture in Korea. Nasal secretions were taken from both the middle nasal meatus and colonized. All analyses were carried out using SPSS software.ResultsPathogens were identified in 178 of the 200 cases. Coagulase-negative staphylococci (CNS were the most cultured bacteria in 127 (66.84% of the 190 total patients after excluding 10 cases of contaminated samples, and methicillin-resistant coagulase-negative staphylococci (MRCNS were found in 48 (25.26%. Staphylococcus aureus was the second most identified pathogen, found in 36 (18.95%, followed by 7 cases (3.68% of methicillin-resistant Staphylococcus aureus (MRSA. The prevalence rate of MRSA in the females was higher than that in the males (RR=4.70; 95% CI, 1.09-20.18, but other demographic factors had no effect on the prevalence rate of MRSA and MRCNS.ConclusionsThe prevalence rate of these pathogens in patients with nasal bone fracture in Korea was similar to other reports. However, few studies have addressed the prevalence rate of CNS and MRCNS in accordance with risk factors or the change in prevalence according to specific prophylaxis against infectious complications. Additional research is needed on the potential connections between clinical factors and microbiological data.

  18. Transnasal endoscopic resection of vascular leiomyomas of the nasal septum

    Directory of Open Access Journals (Sweden)

    Hai-Hong Chen

    2016-01-01

    Conclusion: The endoscope technique offers simple, rapid access to the nasal septum, and excellent visualization; it is a safe, minimally invasive, efficient procedure for removing benign nasal septum tumors that leaves no scar on the face.

  19. Nasal Osteogenic Chondrosarcoma: A Case Report | Adeniji | West ...

    African Journals Online (AJOL)

    At emergency tracheostomy, examination under anaesthesia, meticulous nasal and nasopharyngeal tumour clearance was done. Histopathological examination of the mass revealed osteogenic chondrosarcoma. CONCLUSION: Though rare, osteogenic chondrosarcoma affects nasal bones. Clinically the tumour mimicks ...

  20. Esthetic rhinoplasty as an adjunctive technique in nasal oncoplastic ...

    African Journals Online (AJOL)

    Adham Farouk

    2016-01-15

    Jan 15, 2016 ... Esthetic rhinoplasty;. Oncoplastic surgery nose;. Basal cell carcinoma;. Squamous cell carcinoma;. Nonmelanoma skin cancer;. Nasal reconstruction ... Conclusions: Esthetic rhinoplasty is a useful adjunctive technique in nasal oncoplastic surgery. .... All procedures performed in the study involving human.

  1. A study of Staphylococcus aureus nasal carriage, antibacterial ...

    African Journals Online (AJOL)

    2014-12-30

    Dec 30, 2014 ... substantially enhancing nasal colonization, lung disease and abscess formation and promoting mechanisms of immune evasion.[7]. Antimicrobial ... nasal carriage, investigation of risk factors, and virulence traits among ...

  2. Nasal birth trauma: a review of appropriate treatment.

    LENUS (Irish Health Repository)

    Cashman, E C

    2012-02-01

    The aetiology of nasal deformity has frequently included birth trauma. There is no consensus in the literature as to whether nasal surgery, in the form of closed reduction, is indicated in neonates. The majority of studies in the literature that advocate intervention have inadequate followup periods and there is a paucity of evidence for the adverse effects of conservative management. This case highlights the therapeutic dilemma posed by such nasal injuries in the neonate and, to the best of the authors\\' knowledge, at the time of writing, represents the earliest reported case in the literature of nasal deformity in the neonate. The term nasal deformity is used to denote deformity of the nasal pyramid, soft tissue, and septum. Three main aspects of neonatal nasal deformity are addressed including, firstly, if nasal deformity at birth needs to be addressed, secondly, if left unaltered, what the long-term effects are and, finally, if intervention alters the normal course of midfacial development.

  3. Investigations of glass sealing and reactive air brazing materials for joining high temperature solid oxide fuel cells by dilatometric examinations; Anwendung dilatometrischer Messungen bei der Entwicklung von Glasloten und reaktiven Metallloten zum Fuegen von Hochtemperaturbrennstoffzellen

    Energy Technology Data Exchange (ETDEWEB)

    Reichle, M.S. [Parker Hannifin GmbH, Bietigheim-Bissingen (Germany); Federmann, D. [Forschungszentrum Juelich GmbH, ZAT, Juelich (Germany); Reisgen, U. [RWTH Aachen University, ISF, Aachen (Germany); Koppitz, T.

    2011-03-15

    The principle of operation of solid oxide fuel cells (SOFCs) is very simple. However, the fact that very different materials are used for the individual components requires advanced thermal joining techniques to join them in a functional manner. Two very distinct designs have established themselves for the two different intended applications: decentralised power generation (stationary SOFCs) on the one hand, and power converters for vehicles (mobile SOFCs) on the other hand. As a consequence, alternative techniques for joining the individual components are also required. The principal joining process for the stationary SOFC design consists of joining individual steel plates with a glass sealant in an electrically insulating way so that they form an SOFC stack. For the mobile fuel cell design, the SOFC stack consists of individual thin steel cassettes. The window frame of the cassettes, which is made of ferritic chromium steel, is brazed to the ceramic layer of the zirconium oxide solid electrolyte using a filler metal. The material used is a silver-based brazing filler metal which contains only small amounts of copper oxide (CuO) and titanium hydride (TiH{sub 2}) as wetting agents. Both joining processes must be applicable in normal atmospheric air, i. e. under oxidative conditions. R and D activities continue for improving the efficiency and long-term operational stability of the technology to such an extent that SOFCs will become ready for the energy sector market. The two joining techniques described cannot yet be considered standard processes. They, too, will require continuous improvement with respect to reproducibility, endurance and strength of the joints. The Special Joining Techniques working group at Forschungszentrum Juelich uses specially modified dilatometric techniques as suitable quick replacement methods for studying and measuring the joining characteristics of the materials without having to manufacture complex and expensive SOFC stacks. The shrinkage processes in the glass sealant joints are simulated and measured in the {mu}m range using a special dilatometer. In this way, the amount of glass sealant - which is decisive for tightness and bonding - and the process parameters can be determined in advance. With a vertical dilatometer, the melting behaviour of the reactive silver filler metals is examined with respect to melting point shift, viscosity and void ratio, and as a function of the metal additives (Al) and the process atmosphere.

  4. Development and application of methods and models for the calculation of spatially and temporally highly resolved emissions in Europe; Entwicklung und Anwendung von Methoden und Modellen zur Berechnung von raeumlich und zeitlich hochaufgeloesten Emissionen in Europa

    Energy Technology Data Exchange (ETDEWEB)

    Thiruchittampalam, Balendra

    2014-04-08

    High spatial and temporal resolution models are essential for answering many questions of air quality management and climate modeling. High-resolution emission models are required to determine the concentration of pollutants using chemical transport models, and to quantify the impacts on health and environment and in particular to develop adequate countermeasures. The aim of this work is to develop methods for the calculation of spatially and temporally high-resolved emissions and to apply these exemplarily on a 1 km x 1 km and hourly resolution for the year 2008 in the EU-27 and EFTA countries. The derivation of methods for the spatial and temporal resolution of emissions with corresponding detailed equations is one of the major improvements that have been carried out in the course of this work. The improvement of the spatial distribution of emissions from the point source relevant sectors like energy supply, industry and waste management is achieved by considering sector specific diffuse emission shares. The progress of the spatial distribution of emissions from households is in particular the development of a fuel type weighted distribution over Europe. Another main focus is the development of the spatial distribution of road transport emissions. Due to the restricted access to traffic count data at the European level, methods have been established to provide reliable emissions on grid level for Europe. The progress in the spatial distribution of agricultural emissions is achieved by the consideration of diffuse shares similar to the other point source relevant sectors like energy supply or industry. In addition to the spatial distribution of the emissions the temporal resolution is a main focus of this work, since the state of knowledge of the temporal resolution of emissions in Europe is still rudimentary. Therefore, it was necessary to develop in particular time curves for the hourly resolution of emissions for the main sectors, namely electricity and heat supply, households, commercial, trade and services, road transport and agriculture. One of the main focuses of the development of temporal profiles was specifically to consider temperature data and other parameters. The derivation of the time profiles requires huge amount of indicator data for each time step. Consequently, the goal for the development of temporal profiles in Europe is to derive temperature dependent equations which are capable of generating sector specific profiles for the present as well as for the future. Based on the developed methods, for the first time the visualization of hourly emissions on a 5 km x 5 km for Europe could be shown. The basis for the visualization was the calculation of hourly emissions at a 1 km x 1 km resolution. Due to the lack of quantitative uncertainty assessments, it was necessary to identify the reasons for the lack of uncertainty analysis at the European level and also to describe the possibilities of a quantitative uncertainty analysis for high resolution emission models. Moreover, on the basis of examples it was possible to describe, how the spatial and temporal uncertainty analysis of high resolution emission models can be carried out.

  5. Nasal prosthesis rehabilitation: a case report

    DEFF Research Database (Denmark)

    Jain, Sumeet; Maru, Kavita; Shukla, Jyotsana

    2011-01-01

    Facial defects resulting from neoplasm, congenital malformation or trauma can be restored with facial prosthesis using different materials and retention methods to achieve life-like look and function. A nasal prosthesis can re-establish esthetic form and anatomic contours for mid-facial defects...... the non-surgical rehabilitation, with polymethyl meth-acrylate resin, nasal prosthesis for a patient who received partial rhinectomy as a result of squamous cell carcinoma of the nose. The prosthesis was made to restore the esthetic appearance of the patient with a mechanical retained design using...

  6. The nasal cavity microbiota of healthy adults

    OpenAIRE

    Bassis, Christine M; Tang, Alice L; Young, Vincent B; Pynnonen, Melissa A

    2014-01-01

    Background The microbiota of the nares has been widely studied. However, relatively few studies have investigated the microbiota of the nasal cavity posterior to the nares. This distinct environment has the potential to contain a distinct microbiota and play an important role in health. Results We obtained 35,142 high-quality bacterial 16S rRNA-encoding gene sequence reads from the nasal cavity and oral cavity (the dorsum of the tongue and the buccal mucosa) of 12 healthy adult humans and dep...

  7. A Rare Tumor of Nasal Cavity: Glomangiopericytoma

    Directory of Open Access Journals (Sweden)

    Aysegul Verim

    2014-01-01

    Full Text Available Glomangiopericytoma is a rare vascular neoplasm characterized by a pattern of prominent perivascular growth. A 72-year-old woman was admitted to our clinic complaining of nasal obstruction, frequent epistaxis, and facial pain. A reddish tumor filling the left nasal cavity was observed on endoscopy and treated with endoscopic excision. Microscopically, closely packed cells interspersed with numerous thin-walled, branching staghorn vessels were seen. Glomangiopericytoma is categorized as a borderline low malignancy tumor by WHO classification. Long-term follow-up with systemic examination is necessary due to high risk of recurrence.

  8. [Nasal glial heterotopia: Clinical and morphological characteristics].

    Science.gov (United States)

    Bykova, V P; Bakhtin, A A; Polyakov, D P; Yunusov, A S; Daikhes, N A

    The paper describes a case of nasal glial heterotopia in a 10-month-old girl with a mixed (intranasal and subcutaneous) localization, which is accompanied by the divergence of the nasal bones. Histological examination supplemented by immunohistochemical reactions with antibodies to vimentin, S100 protein, neuron-specific enolase, as well as Ki-67 and smooth muscle actin confirmed the neural nature of the tumor. Fields of mature astrocytic glia including individual cells with neuronal differentiation were found among the fibrous and fibrovascular tissues. The paper provides a brief overview of the discussed pathology.

  9. STRATEGIES AND PROSPECTS OF NASAL DRUG DELIVERY SYSTEMS

    OpenAIRE

    Gannu Praveen Kumar

    2012-01-01

    The recent advancement of nasal drug delivery systems has increased enormously and is gaining significant importance. Intranasal therapy has been an accepted form of treatment in the Ayurvedic system of Indian Medicine. The non-invasive delivery of nasal drug delivery systems made to exploit for the development of successful treatment. The advantages, disadvantages, mechanism of action and application of nasal drug delivery system in local delivery, systematic delivery, nasal vaccines and CNS...

  10. Linear open-loop and closed-loop control theory. Modelling of control paths, robust stability, design of robust controllers, trajectory control with follow-up contorl, polynomial description of MIMO systems, time discrete control loops and scanning control loops; Lineare Regelungs- und Steuerungstheorie. Modellierung von Regelstrecken, Robuste Stabilitaet und Entwurf robuster Regler, Trajektoriensteuerung mit Folgeregelung, Polynomiale Beschreibung von MIMO-Systemen, Zeitdiskrete und Abtastregelkreise

    Energy Technology Data Exchange (ETDEWEB)

    Reinschke, K. [Technische Univ. Dresden (Germany). Inst. fuer Regelungs- und Streuerungstheorie

    2006-07-01

    Zusammenhaenge, die sowohl den Entwurf robuster stabilisierender Regler als auch die Trajektoriensteuerung mit Folgeregelung sowie die zeitkontinuierliche Behandlung von Abtastregelkreisen ermoeglichen. Zahlreiche Beispiele illustrieren die Anwendung der allgemeinen Gesetzmaessigkeiten. (orig.)

  11. Planning processes with integrated evaluation of climate and air; Einbindung und Bewertung von Klima und Luft in Plannungsablaeufe

    Energy Technology Data Exchange (ETDEWEB)

    Katzschner, L. [Kassel Univ. (Gesamthochschule) (Germany). Fachbereich 13 - Stadt- und Landschaftsplanung

    1997-09-01

    More and more often, plannings require climate statements which are suitable to be considered in the weighing of the different factors. The paper makes climate assessment proposals permitting a qualitative and quantitative judgement. Parameters employed are the physiologically equivalent temperature (PET) as well as, increasingly, statements regarding the quality of ventilation. Examples illustrate how space-related planning clues can be derived from climate function maps. The basis for this are climate-geographic surveys (orohydrographic analysis, topographic gradient determination etc.), as well as the analysis of dynamic parameters (air conduction paths and barriers) and thermal parameters (areas warming up excessively, areas of cold and fresh air generation). Linking of these aspects yields a climate function map. It is used to prepare a planning recommendations map which differentiates and evaluates climate-ecological sensitivities. (orig.) [Deutsch] Im Rahmen von Planungsprozessen werden immer haeufiger Klimaaussagen verlangt, die in die Planungsabwaegung Eingang finden koennen. Dazu werden Klimabewertungsvorschlaege fuer eine qualitative und quantitative Beurteilung gemacht. Anwendung finden die bioklimatischen Komplexgroessen und vermehrt Aussagen zur Belueftungsqualitaet. Beispiele verdeutlichen, wie sich aus den Klimafunktionskarten raeumliche Planungshinweise ableiten lassen. Grundlage sind klimageographische Erhebungen (orohydrographische Analyse, topographische Gradientenbestimmung usw.) sowie die Analyse der dynamischen (Luftleitbahnen und Barrieren) und thermischen Parameter (Ueberwaermungsgebiete, Kalt- und Frischluftentstehungsgebiete). In einer Verknuepfung dieser Aspekte wird die Klimafunktionskarte erstellt, aus der die Planungshinweiskarte abgeleitet wird, die klimaoekologische Empfindlichkeiten differenziert und bewertet. (orig.)

  12. The NOFLO trial: low-flow nasal prongs therapy in weaning nasal continuous positive airway pressure in preterm infants.

    LENUS (Irish Health Repository)

    O'Donnell, Sinéad M

    2013-07-01

    To determine if low-flow nasal prongs therapy with room air, compared with no treatment, facilitates weaning from nasal continuous positive airway pressure (NCPAP) in very low birth weight (VLBW, birth weight <1500 g) infants.

  13. NORMAL NASAL GENE EXPRESSION LEVELS USING CDNA ARRAY TECHNOLOGY

    Science.gov (United States)

    Normal Nasal Gene Expression Levels Using cDNA Array Technology. The nasal epithelium is a target site for chemically-induced toxicity and carcinogenicity. To detect and analyze genetic events which contribute to nasal tumor development, we first defined the gene expressi...

  14. Staphylococcus aureus and the ecology of the nasal microbiome

    DEFF Research Database (Denmark)

    Liu, Cindy M; Price, Lance B; Hungate, Bruce A

    2015-01-01

    The human microbiome can play a key role in host susceptibility to pathogens, including in the nasal cavity, a site favored by Staphylococcus aureus. However, what determines our resident nasal microbiota-the host or the environment-and can interactions among nasal bacteria determine S. aureus...

  15. Nasal carriage of multi-drug resistant Staphylococcus aureus in ...

    African Journals Online (AJOL)

    Background: Nasal Staphylococcus aureus is a major source of community and hospital associated staphylococcal infections. This study determined the prevalence of nasal S. aureus isolates and investigated their antimicrobial resistance profile in healthy volunteers. Methods: Nasal specimens of healthy volunteers in ...

  16. Effects of retro-nasal aroma release on satiation

    NARCIS (Netherlands)

    Ruijschop, R.; Boelrijk, A.E.M.; Ru, de J.A.; Graaf, de C.; Westerterp-Plantenga, M.

    2008-01-01

    It is suggested that the brain response of a food odour sensed retro-nasally is related to satiation. The extent of retro-nasal aroma release during consumption depends on the physical structure of a food, i.e. solid foods generate a longer, more pronounced retro-nasal aroma release than liquid

  17. Human nasal rhinosporidiosis: a case report from Malawi | Sefu ...

    African Journals Online (AJOL)

    Patient presented with long standing history of nasal obstruction and intermittent epistaxis for three years. Diagnosis was confirmed by histopathological examination and he was successfully treated by complete surgical excision. This was a very unusual cause of nasal masses in our setting. Nasal rhinosporidioss lesions ...

  18. Enhancing the safety and efficiency of the driving gear of coal mining machinery by using water as a hydraulic fluid and enhancing the reliability of scraper-chain conveyors; Erhoehung der Sicherheit und Leistungsfaehigkeit der Antriebstechnik von Arbeitsmaschinen durch Verwendung von Wasserhydraulik sowie Erhoehung der Zuverlaessigkeit der Kettenkratzerfoerderer

    Energy Technology Data Exchange (ETDEWEB)

    Reichel, J.; Boeing, R.; Graetz, A.; Loehning, H.D.; Plum, D.

    1997-12-31

    The objective pursued is to increasingly use water or high water-content fluids as a substitute for other hydraulic fluids in driving gear of mining machinery. The state of the art of the technology is represented only by individual solutions achieved for given purposes which are not suitable for other applications, let alone for coal mining machinery. The research project was to identify hydraulic components that will permit the use of water or watery substances as a hydraulic fluid in mining applications. The components have been found and further developed, and finally systems with linear and rotatory drives have been tested at various test facilities in order to derive information on the system behaviour of pressurized fluids and machinery components and their suitability for coal mining applications. (orig./CB) [Deutsch] In der untertaegigen Antriebstechnik sollen vermehrt Wasser und wasserhaltige Fluessigkeiten eingesetzt werden. Der Stand der Technik fuehrt bei der Anwendung von Wasserhydraulik immer wieder nur Einzelloesungen auf, die nicht allgemein und insbesondere im Steinkohlenbergbau angewendet werden koennen. Im Rahmen dieses Forschungsvorhabens wurden fuer die Wasserhydraulik geeignete Komponenten untersucht, weiterentwickelt und schliesslich Systeme mit linearen und rotatorischen Antrieben auf verschiedenen Pruefstaenden erprobt, um Aussagen ueber das Systemverhalten von Druckfluessigkeit und Bauelementen fuer Bergbauanwendungen zu bekommen. (orig./MSK)

  19. Cooling of high temperature superconductors below 60 K by means of a two-stage cryogenic mixed refrigerant cascade; Kuehlung von Hochtemperatursupraleitern unterhalb von 60 K mittels einer zweistufigen Gemischkaeltekaskade

    Energy Technology Data Exchange (ETDEWEB)

    Kochenburger, T.M. [Karlsruher Institut fuer Technologie (KIT), Karlsruhe (Germany). Inst. fuer Technische Thermodynamik und Kaeltetechnik (ITTK); Grohmann, S. [Karlsruher Institut fuer Technologie (KIT), Karlsruhe (Germany). Inst. fuer Technische Thermodynamik und Kaeltetechnik (ITTK); Karlsruher Institut fuer Technologie (KIT), Eggenstein-Leopoldshafen (Germany). Inst. fuer Technische Physik (ITEP)

    2015-07-01

    High temperature superconductors enable the efficient transmission of electrical energy in urban and industrial networks. It is the availability of simple, reliable and at the same time efficient cooling methods prerequisite for the application of this technology. At operating temperatures 65-80 K is the cooling currently mostly implemented by liquid nitrogen, large-scale turbo-Brayton plants or batteries of regenerative cryocooler; however, all these options for applications in the range of a few kW of required cooling capacity have thermodynamic, economic and practical limitations. In addition, a further lowering the cooling temperature below 60 K is desirable to increase the current density in the superconductors. Two-stage cryogenic mixed refrigerant cascade offer the potential for a reliable and easily scalable alternative for refrigeration in this temperature range. The first stage of the considered process consists of a classic mixture refrigeration cycle to pre-cool to 120 K. The second stage operates in the low temperature range up to 55 K with a mixture of nitrogen, oxygen and neon at high pressures. This paper compares on the basis of experimental data, the performance of combustible and non-combustible mixtures in the precooling level. The applicability of various equations of state for modeling of phase behavior of mixtures is discussed. [German] Hochtemperatursupraleiter ermoeglichen den effizienten Transport elektrischer Energie in urbanen und industriellen Netzen. Dabei ist die Verfuegbarkeit von einfachen, zuverlaessigen und gleichzeitig effizienten Kuehlmethoden Voraussetzung fuer die Anwendung dieser Technologie. Bei Betriebstemperaturen von 65 - 80 K wird die Kuehlung derzeit meist durch Fluessigstickstoff, grossskalige Turbo-Brayton-Anlagen oder Batterien regenerativer Kleinkuehler realisiert; jedoch haben alle diese Optionen fuer Anwendungen im Bereich von einigen kW an erforderlicher Kaelteleistung thermodynamische, oekonomische und

  20. Risk factors for nasal malignancies in German men: the South-German Nasal cancer study.

    Science.gov (United States)

    Greiser, Eberhard M; Greiser, Karin Halina; Ahrens, Wolfgang; Hagen, Rudolf; Lazszig, Roland; Maier, Heinz; Schick, Bernhard; Zenner, Hans Peter

    2012-11-06

    There are few studies of the effects of nasal snuff and environmental factors on the risk of nasal cancer. This study aimed to investigate the impact of using nasal snuff and of other risk factors on the risk of nasal cancer in German men. A population-based case-control study was conducted in the German Federal States of Bavaria and Baden-Württemberg. Tumor registries and ear, nose and throat departments provided access to patients born in 1926 or later. Telephone interviews were conducted with 427 cases (mean age 62.1 years) and 2.401 population-based controls (mean age 60.8 years). Ever-use of nasal snuff was associated with an odds ratio (OR) for nasal cancer of 1.45 (95% confidence interval [CI] 0.88-2.38) in the total study population, whereas OR in smokers was 2.01 (95% CI 1.00-4.02) and in never smokers was 1.10 (95% CI 0.43-2.80). The OR in ever-smokers vs. never-smokers was 1.60 (95% CI 1.24-2.07), with an OR of 1.06 (95% CI 1.05-1.07) per pack-year smoked, and the risk was significantly decreased after quitting smoking. Exposure to hardwood dust for at least 1 year resulted in an OR of 2.33 (95% CI 1.40-3.91) in the total population, which was further increased in never-smokers (OR 4.89, 95% CI 1.92-12.49) in analyses stratified by smoking status. The OR for nasal cancer after exposure to organic solvents for at least 1 year was 1.53 (1.17-2.01). Ever-use of nasal sprays/nasal lavage for at least 1 month rendered an OR of 1.59 (1.04-2.44). The OR after use of insecticides in homes was 1.48 (95% CI 1.04-2.11). Smoking and exposure to hardwood dust were confirmed as risk factors for nasal carcinoma. There is evidence that exposure to organic solvents, and in-house use of insecticides could represent novel risk factors. Exposure to asbestos and use of nasal snuff were risk factors in smokers only.

  1. High Flow Nasal Cannulae in preterm infants

    Directory of Open Access Journals (Sweden)

    F. Ciuffini

    2013-06-01

    Full Text Available Despite of improved survival of premature infants, the incidence of long term pulmonary complications, mostly associated with ventilation-induced lung injury, remains high. Non invasive ventilation (NIV is able to reduce the adverse effects of mechanical ventilation. Although nasal continuous positive airway pressure (NCPAP is an effective mode of NIV, traumatic nasal complications and intolerance of the nasal interface are common. Recently high flow nasal cannula (HFNC is emerging as an efficient, better tolerated form of NIV, allowing better access to the baby’s face, which may improve nursing, feeding and bonding. The aim of this review is to discuss the available evidence of effectiveness and safety of HFNC in preterm newborns with respiratory distress syndrome (RDS. It is known that distending pressure generated by HFNC increases with increasing flow rate and decreasing infant size and varies according to the amount of leaks by nose and mouth. The effects of HFNC on lung mechanics, its clinical efficacy and safety are still insufficiently investigated. In conclusion, there is a growing evidence of the feasibility of HFNC as an alternative mode of NIV. However, further larger randomized trials are required, before being able to recommend HFNC in the treatment of moderate respiratory distress of preterm infants.

  2. Fracture of nasal bones: an epidemiologic analysis

    Directory of Open Access Journals (Sweden)

    Fornazieri, Marco Aurélio

    2008-12-01

    Full Text Available Introduction: One of the most common diseases in the otorhinolaryngology emergency room is the nasal bones fracture. The peak of incidence is between 15 and 25 years of age. Generally men are more affected. Objective: To analyze the age, gender and the most frequent causes of nasal fractures evaluated in the otorhinolaryngology service of a tertiary hospital. Method: Retrospective study of records of the patients with nasal fracture diagnosis treated between July 1st, 2003 and July 1st, 2007. Results: 167 patients with nasal bones fracture were included in the study, including 134 men and 33 women. Violence was the most frequent cause, with 55 cases (32.9%, followed by fall from their own height, with 33 cases (19.7%, and motorcycle accident, 14 cases (8.4%. The most common age was between 21 and 39 years (46.1%. Conclusion: Male, age between 21 and 39 years and violence are the most common characteristics found in our service. Motorcycle accidents also play an important role in this affection.

  3. Squamous Cell Carcinoma of the Nasal Vestibule

    DEFF Research Database (Denmark)

    Horsmans, J D; Godballe, C; Jørgensen, K E

    1999-01-01

    From 1978 to 1992, 66 patients (32 women and 34 men) were treated for carcinoma of the nasal vestibule at Odense University Hospital. The treatment was radiotherapy (41 patients), surgery (13 patients) or a combination of the two modalities (12 patients). Twenty-one patients (32%) developed...

  4. Tumor relapse present in oncologic nasal repair

    International Nuclear Information System (INIS)

    Galvez Chavez, Julio Cesar; Sanchez Wals, Lenia; Monzon Fernandez, Abel Nicolas; Morales Tirado, Roxana

    2009-01-01

    Tumor relapse is one of the more fearsome complications of the oncologic course and also to obscure the life prognosis, causing the loss of many reconstructions and of exhausting the repairing surgical possibilities. The aim of this study was to determine the relapse frequency, the repercussion on the repair and the subsequent medical course of patients operated on malign nasal tumors

  5. Nasal symptoms following endoscopic transsphenoidal pituitary surgery: assessment using the General Nasal Patient Inventory.

    Science.gov (United States)

    Wang, Yi Yuen; Srirathan, Vinothan; Tirr, Erica; Kearney, Tara; Gnanalingham, Kanna K

    2011-04-01

    The endoscopic approach for pituitary tumors is a recent innovation and is said to reduce the nasal trauma associated with transnasal transsphenoidal surgery. The authors assessed the temporal changes in the rhinological symptoms following endoscopic transsphenoidal surgery for pituitary lesions, using the General Nasal Patient Inventory (GNPI). The GNPI was administered to 88 consecutive patients undergoing endoscopic transsphenoidal surgery at 3 time points (presurgery, 3-6 months postsurgery, and at final follow-up). The total GNPI score and the scores for the individual GNPI questions were calculated and differences between groups were assessed once before surgery, several months after surgery, and at final follow-up. Of a maximum possible score of 135, the mean GNPI score at 3-6 months postsurgery was only 12.9 ± 12 and was not significantly different from the preoperative score (10.4 ± 13) or final follow-up score (10.3 ± 10). Patients with functioning tumors had higher GNPI scores than those with nonfunctioning tumors for each of these time points (p surgery, with partial recovery (nasal sores and bleeding) or complete recovery (nasal blockage, painful sinuses, and unpleasant nasal smell) by final follow-up (p transsphenoidal surgery is a well-tolerated minimally invasive procedure for pituitary fossa lesions. Overall patient-assessed nasal symptoms do not change, but some individual symptoms may show a mild worsening or overall improvement.

  6. Development of probabilistic methods for safety assessment of nuclear power plants; Weiterentwicklung probabilistischer Methoden zur Sicherheitsbeurteilung von Kernkraftwerken

    Energy Technology Data Exchange (ETDEWEB)

    Balfanz, H.P. [Technischer Ueberwachungs-Verein Norddeutschland e.V., Hamburg (Germany); Boehme, E. [Technischer Ueberwachungs-Verein Norddeutschland e.V., Hamburg (Germany); Fuhrmann, C. [Technischer Ueberwachungs-Verein Norddeutschland e.V., Hamburg (Germany); Musekamp, W. [Technischer Ueberwachungs-Verein Norddeutschland e.V., Hamburg (Germany); Neumann, L. [Technischer Ueberwachungs-Verein Norddeutschland e.V., Hamburg (Germany); Rumpf, J. [Technischer Ueberwachungs-Verein Norddeutschland e.V., Hamburg (Germany)

    1997-07-01

    unmittelbaren Ereignisbewertung einzusetzen. Die Diskussion mit Kraftwerksbetreibern zur Umsetzung dieses Konzeptes im Anlagenbetrieb wird fortgesetzt. Eine entsprechende Uebernahme dieses Ansatzes in den PSA-Leitfaden haben wir ebenfalls empfohlen. Organisations- und Managementfaktoren haben gleichermassen einen signifikanten Einfluss auf Unfallablaeufe. Dies zeigen Erfahrungen in unterschiedlichsten Industriebereichen. Da diese Faktoren explizit nicht messbar sind, finden sie in der heute ueblichen PSA keine Anwendung. Zur Bewertung und Beeinflussung dieser risikorelevanten Faktoren sind bereits umfangreiche Entwicklungsarbeiten durchgefuehrt worden. Diese Arbeiten zeigen die Bedeutung der gezielten Auswertung von Betriebserfahrungen und von Unfallablaeufen unter dem besonderen Aspekt der `Root-Cause`-Analyse auf. In diesem Rahmen koennen auch Defizite in der Organisation und im Management aufgezeigt werden. Durch eine intensive Einbindung des Kraftwerkspersonals in diesen Analyseprozess koennen derartige Defizite abgebaut werden. (orig./DG)

  7. Shock, diaschisis and von Monakow

    Directory of Open Access Journals (Sweden)

    Eliasz Engelhardt

    2013-07-01

    Full Text Available The concept of shock apparently emerged in the middle of the 18th century (Whyett as an occurrence observed experimentally after spinal cord transection, and identified as "shock" phenomenon one century later (Hall. The concept was extended (Brown-Séquard and it was suggested that brain lesions caused functional rupture in regions distant from the injured one ("action à distance". The term "diaschisis" (von Monakow, proposed as a new modality of shock, had its concept broadened, underpinned by observations of patients, aiming at distinguishing between symptoms of focal brain lesions and transitory effects they produced, attributable to depression of distant parts of the brain connected to the injured area. Presently, diaschisis is related mainly to cerebrovascular lesions and classified according to the connection fibers involved, as proposed by von Monakow. Depression of metabolism and blood flow in regions anatomically separated, but related by connections with the lesion, allows observing diaschisis with neuroimaging.

  8. New CFD tools to evaluate nasal airflow.

    Science.gov (United States)

    Burgos, M A; Sanmiguel-Rojas, E; Del Pino, C; Sevilla-García, M A; Esteban-Ortega, F

    2017-08-01

    Computational fluid dynamics (CFD) is a mathematical tool to analyse airflow. As currently CFD is not a usual tool for rhinologists, a group of engineers in collaboration with experts in Rhinology have developed a very intuitive CFD software. The program MECOMLAND ® only required snapshots from the patient's cross-sectional (tomographic) images, being the output those results originated by CFD, such as airflow distributions, velocity profiles, pressure, temperature, or wall shear stress. This is useful complementary information to cover diagnosis, prognosis, or follow-up of nasal pathologies based on quantitative magnitudes linked to airflow. In addition, the user-friendly environment NOSELAND ® helps the medical assessment significantly in the post-processing phase with dynamic reports using a 3D endoscopic view. Specialists in Rhinology have been asked for a more intuitive, simple, powerful CFD software to offer more quality and precision in their work to evaluate the nasal airflow. We present MECOMLAND ® and NOSELAND ® which have all the expected characteristics to fulfil this demand and offer a proper assessment with the maximum of quality plus safety for the patient. These programs represent a non-invasive, low-cost (as the CT scan is already performed in every patient) alternative for the functional study of the difficult rhinologic case. To validate the software, we studied two groups of patients from the Ear Nose Throat clinic, a first group with normal noses and a second group presenting septal deviations. Wall shear stresses are lower in the cases of normal noses in comparison with those for septal deviation. Besides, velocity field distributions, pressure drop between nasopharynx and the ambient, and flow rates in each nostril were different among the nasal cavities in the two groups. These software modules open up a promising future to simulate the nasal airflow behaviour in virtual surgery intervention scenarios under different pressure or

  9. Acoustic Analysis of Nasal Vowels in Monguor Language

    Science.gov (United States)

    Zhang, Hanbin

    2017-09-01

    The purpose of the study is to analyze the spectrum characteristics and acoustic features for the nasal vowels [ɑ˜] and [ɔ˜] in Monguor language. On the base of acoustic parameter database of the Monguor speech, the study finds out that there are five main zero-pole pairs appearing for the nasal vowel [ɔ˜] and two zero-pole pairs appear for the nasal vowel [ɔ˜]. The results of regression analysis demonstrate that the duration of the nasal vowel [ɔ˜] or the nasal vowel [ɔ˜] can be predicted by its F1, F2 and F3 respectively.

  10. Von Hippel–Lindau disease

    Directory of Open Access Journals (Sweden)

    Juhara Haron

    2017-04-01

    Full Text Available Von Hippel–Lindau (VHL disease is a rare autosomal dominantly inherited multisystem disorder characterised by the development of a variety of benign and malignant tumours. We report a case of VHL disease that was inherited by a daughter from her father, who both presented at a young age with progressive headache and were found to have a posterior fossa haemangioblastoma (HB on magnetic resonance imaging (MRI. Multiple benign pancreatic and renal cysts were also noted in both patients.

  11. Microfinance als Geflecht von Anreizproblemen

    OpenAIRE

    Schmidt, Reinhard H.; Tschach, Ingo E.

    2001-01-01

    Während sich die Entwicklungsfinanzierung in Theorie und Praxis generell mit dem Finanzwesen in Entwicklungs- und Transformationsländern befasst, steht im Teilgebiet der Microfinance die Frage im Vordergrund, wie in diesen Ländern der Zugang ärmerer Bevölkerungsgruppen und speziell von Klein- und Kleinstunternehmer(innen), Kleinbauern und sonstigen wirtschaftlich Selbständigen aus eher niedrigen sozialen Schichten zu Kredit und anderen Finanzdiensleistungen verbessert werden kann. Obwohl es e...

  12. Moose von Inselbergen in Benin

    OpenAIRE

    Frahm, Jan-Peter; Porembski, Stefan

    1998-01-01

    Acht Leber- und zehn Laubmoosarten werden von Inselbergen aus Benin angegeben. Fünf der Lebermoose (Acrolejeunea emergens, Riccia atropurpurea, R. congoana, R. discolor, R. moenkemeyeri) und alle Laubmoose (Archidium ohioense, Brachymenium acuminatum, B. exile, Bryum arachnoideum, B. argenteum, Bryum deperssum, Garckea moenkemeyeri, Hyophila involuta, Philonotis mniobryoides und Weissia cf. edentula) werden neu für Benin angegeben. Eight liverworts and ten mosses are reported from inselber...

  13. Dr. von Braun Briefing Walt Disney

    Science.gov (United States)

    1965-01-01

    Dr. von Braun began his association with Walt Disney in the 1950s when the rocket scientist appeared in three Disney television productions related to the exploration of space. Years later, Dr. von Braun invited Disney and his associates to tour the Marshall Space Flight Center (MSFC) in Huntsville, Alabama. This photograph is dated April 13, 1965. From left are R.J. Schwinghamer from the MSFC, Disney, B.J. Bernight, and Dr. von Braun.

  14. Wohnquartiersbeschreibung: ein Instrument zur Regionalisierung von Nachbarschaften

    OpenAIRE

    Hoffmeyer-Zlotnik, Jürgen H. P.

    2001-01-01

    'Ausgehend von der Annahme, daß soziale Differenzierung sich in räumlicher Differenzierung niederschlägt, bietet eine Beschreibung der Struktur des näheren Wohnumfeldes die Möglichkeit, das Wohnquartier als Handlungsraum und Sozialisationsinstanz zur Interpretation von Umfragedaten zu nutzen. Das vorliegende Instrumentarium erlaubt es, das Wohnquartier unabhängig von Zensusdaten über Merkmale, die in der eigenen Umfrage erhoben werden, zu charakterisieren.' (Autorenreferat) 'The general hy...

  15. Die häufigsten Fehler bei der FMEA-Anwendung und wie ich sie vermeiden kann

    OpenAIRE

    Schloske, Alexander

    2010-01-01

    Die FMEA stellt heutzutage eines der wichtigsten Werkzeuge des präventiven Risikomanagements dar. Die universell anwendbare Vorgehensweise des VDA hat sich dabei in der Industrie etabliert. Der Beitrag beschreibt aus der Sicht von 20 Jahren FMEA-Erfahrung, wie die FMEA zielführend erstellt wird und mit welchen Tipps und Tricks eine effiziente und effektive FMEA-Erstellung ermöglicht wird.

  16. Laser beam welding of high strength aluminium-lithium alloys; Laserstrahlschweissen von hochfesten Aluminium-Lithium Legierungen

    Energy Technology Data Exchange (ETDEWEB)

    Enz, Josephin

    2012-07-01

    The present development in aircraft industry determined by the demand for a higher cost-effectiveness. Laser beam welding is one of the most promising joining technologies for the application in the aircraft industry through the considerable reduction of the production costs. Furthermore the weight of an aircraft structure can be reduced by the use of light and high strength aluminium alloys. This paper deals with the development of a process for the laser beam welding of a skin-stringer-joint where the Al-Li-alloy AA2196 is used as stringer material and the Al-Li-alloy AA2198 is used as skin and stringer material. By the use of design of experiments the optimal welding process parameters for different material combinations were determined which will be used for the welding of a 5-stringer panel. Therefore the weld seams of the joints were tested for irregularities and microstructural characteristics. In addition several mechanical tests were performed, which define the quality of the welded joint. Furthermore the influence of the oxide layer and the welding preparation on the welding performance was investigated. (orig.) [German] Die derzeitigen Entwicklungen im Flugzeugbau werden durch die allgemeine Forderung nach einer Steigerung der Wirtschaftlichkeit bestimmt. Das Laserstrahlschweissen ist dabei eines der vielversprechendsten Fuegeverfahren fuer die Anwendung im Flugzeugbau durch das die Herstellungskosten deutlich reduziert werden koennen. Zudem kann durch die Verwendung von leichten und hochfesten Aluminium-Legierungen das Gewicht einer Flugzeugstruktur zusaetzlich reduziert werden. Die vorliegende Arbeit befasst sich mit der Entwicklung eines Prozesses zum Laserstrahlschweissen einer Skin-Stringer-Verbindung aus den Aluminium-Lithium-Legierungen AA2196 (als Stringer-Werkstoff) und AA2198 (als Skin- und Stringer-Werkstoff). Unter Verwendung der statistischen Versuchsplanung wurden die optimalen Einstellungen der Schweissprozessparameter fuer die

  17. Advanced energy conversion and application - Decentralized energy systems. Papers; Fortschrittliche Energiewandlung und -anwendung - Schwerpunkt: Dezentrale Energiesysteme. Vortraege

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2001-07-01

    Decentralized energy systems is the major topic of this VDI report which contains the proceedings of the VDI conference on advanced energy conversion and application. The decentralized energy systems are in the focus because it is expected that they will gain in significance in the course of restructuring and liberalisation of the energy markets and growing commitment to greenhouse gas mitigation. The subjects of the papers are the cogeneration technology in general, and specific systems for combined generation of heat, power and cold,(CHPC systems), systems for renewable energy generation, industrial energy technology, and analysis and optimization of energy systems. The report is intended to serve as a source of guidance and reference for manufacturers and operators of decentralized energy systems, for decision-making on energy policy, and for the energy industry, counselling firms and regulatory/surveillance bodies, and members of universities involved in relevant research and development work. (orig./CB) [German] Themenschwerpunkt des VDI-Berichts sind die dezentralen Energiesysteme, die im Spannungsfeld von fortschreitender Liberalisierung der Energiemaerkte und der Bemuehungen um die Reduzierung von Emissionen an Bedeutung gewinnen. Dabei widmen sich die Beitraege den Systemen zur Kraft-Waerme-Kaelte-Kopplung und zur Nutzung erneuerbarer Energie sowie der industriellen Energietechnik und der Analyse und Optimierung von Energiesystemen. Der Bericht wendet sich an Hersteller und Betreiber dezentraler Energieanlagen, an Entscheidungstraeger aus Politik und Wirtschaft, an Berater und Ueberwachungsinstitutionen sowie an auf diesem Gebiet taetige Hochschullehrer und -mitarbeiter. (orig.)

  18. Measurement with nasal scintigraphy of nasal mucociliary clearance in normal man

    International Nuclear Information System (INIS)

    Murai, Sumiko

    1989-01-01

    Nasal mucociliary function was evaluated by nasal scintigraphy in normal subjects. A microdrop of HSA or saline labelled with 99m Tc was dripped into the middle part of each middle meatus in the nasal cavity and its clearance was observed by scinticamera. The accumulated concentration of RI was determined every 30 seconds for 10 minutes. The changes of accumulated concentration were studied, and a curve of decreasing RI-counts was obtained, with the 'clearance rate' defined as 100% for the count at the initial 30 seconds and 'half time' as the time when radioactivity was reduced to one half the initial count. Nasal resistance was measured by rhinomanometry with the oscillation method. In nonsmokers, 10μl of saline was cleared (78.0±10.4%) significantly faster than 10μl of HSA (59.9±24.6%), and there was no significant difference in the clearance between 10μl and 5μl of HSA (55.9±27.7%). In smakers, the mucociliary clearance of 10μl of HSA and saline was significantly lower than in nonsmokers. The clearance of 10μl of HSA reflects a pathological state much better than that of 5μl. In nonsmokers, there is a significant negative correlation between nasal resistance and clearance rate, suggesting that the more patent the nose, the faster the mucociliary clearance. When both nostrils were closed, the clearance rate was significantly depressed. When one nostril was closed, there was no significant effect on clearance. Nasal resistance was decreased by exercise with a bicycle ergometer. Nasal mucociliary clearance was slightly decreased after exercise but not significantly so. (J.P.N.)

  19. Nasal Carriage of 200 Patients with Nasal Bone Fracture in Korea

    Directory of Open Access Journals (Sweden)

    Jun Wook Lee

    2013-09-01

    Full Text Available Background Pathogens in the nasal cavity during nasal surgery could lead to a systemicinfectious condition, such as bacteremia, nosocomial infection, or toxic shock syndrome.However, there is no research about the prevalence of nasal carriage in patients with nasalbone fracture.Methods This was a prospective, double-blind, randomized study about the rate of nasalcarriage in 200 patients with nasal bone fracture in Korea. Nasal secretions were taken fromboth the middle nasal meatus and colonized. All analyses were carried out using SPSS software.Results Pathogens were identified in 178 of the 200 cases. Coagulase-negative staphylococci(CNS were the most cultured bacteria in 127 (66.84% of the 190 total patients after excluding10 cases of contaminated samples, and methicillin-resistant coagulase-negative staphylococci(MRCNS were found in 48 (25.26%. Staphylococcus aureus was the second mostidentified pathogen, found in 36 (18.95%, followed by 7 cases (3.68% of methicillin-resistantStaphylococcus aureus (MRSA. The prevalence rate of MRSA in the females was higher thanthat in the males (RR=4.70; 95% CI, 1.09-20.18, but other demographic factors had no effecton the prevalence rate of MRSA and MRCNS.Conclusions The prevalence rate of these pathogens in patients with nasal bone fracture inKorea was similar to other reports. However, few studies have addressed the prevalence rateof CNS and MRCNS in accordance with risk factors or the change in prevalence according tospecific prophylaxis against infectious complications. Additional research is needed on thepotential connections between clinical factors and microbiological data.

  20. UIS Baden-Wuerttemberg. Project AJA. Application of JAVA-based and other efficient solutions in the areas of environment, traffic and administration. Phase V 2004; UIS Baden-Wuerttemberg. Projekt AJA. Anwendung JAVA-basierter und anderer leistungsfaehiger Loesungen in den Bereichen Umwelt, Verkehr und Verwaltung. Phase V 2004

    Energy Technology Data Exchange (ETDEWEB)

    Mayer-Foell, R.; Keitel, A.; Geiger, W. (eds.)

    2004-12-01

    Bundeslaendern die Umsetzung von Verwaltungsreformen - in Baden-Wuerttemberg der Vollzug des Verwaltungsstruktur-Reformgesetzes (VRG) - sowie die Umsetzung von e-Government-Konzepten derzeit zu zusaetzlichen Anforderungen an die Verwaltung und ihre IuK-Technik. Durch den Einsatz innovativer Informationstechnologien kann in vielen Bereichen ein bedeutender Beitrag zur Erfuellung dieser Anforderungen geleistet werden; genannt seien hier Portal-, Content-Management- und Integrations-Technologien sowie neue Techniken fuer den Web-basierten und mobilen Zugriff auf Informationen. Entwicklung uf Pflege der neuen Informations- und Kommunikationssysteme erfordern oft nicht unerhebliche Mittel. Aufgrund der knappen Haushaltslage der Gebietskoerperschaften koennen diese Mittel von den einzelnen zustaendigen Stellen zunehmend nicht mehr aufgebracht werden. Auch wuerden Einzelentwicklungen nicht den Anforderungen zum sparsamen Umgang mit Haushaltsmitteln und groesstmoeglicher Effektivitaet der eingesetzten Mittel entsprechen. Ein wichtiges Mittel, um diese Herausforderung zu bewaeltigen, ist die verstaerkte Zusammenarbeit der Gebietskoerperschaften bei der Entwicklung und Pflege der Informationssysteme. Um die Zusammenarbeit innerhalb des Landes Baden-Wuerttemberg sowie mit dem Bund und anderen Laendern zu foerdern, wurde Ende 1999 das F+E-Projekt AJA (Anwendung JAVA-basierter und anderer leistungsfaehiger Loesungen in den Bereichen Umwelt, Verkehr und Verwaltung) gegruendet. Das Projekt AJA ist im Jahr 2004 in seine fuenfte Phase gegangen und wird mit dieser Phase abgeschlossen. Der vorliegende Bericht ist die Projektdokumentation der Phase V von AJA im Jahr 2004. Er gibt die Aufgabenstellungen und die Ergebnisse der 19 F+E-Arbeiten wieder. (orig.)

  1. Adenoma pleomórfico de septo nasal: relato de caso Pleomorphic adenoma of the nasal septum: a case report

    Directory of Open Access Journals (Sweden)

    Mauren P. Rocha

    2004-06-01

    Full Text Available As neoplasias nasais são bastante raras. Os tumores mais observados na cavidade nasal são papilomas epiteliais, angiomas, carcinoma de células transicionais, carcinoma pavimentoso e adenocarcinoma. O adenoma pleomórfico pertence ao grupo de tumores que aparecem com menor freqüência na fossa nasal, e é o tumor benigno glandular mais comum originado na cabeça e pescoço. A apresentação clínica típica dos pacientes com adenoma pleomórfico do septo nasal é de obstrução nasal unilateral, epistaxe e massa indolor na cavidade nasal. Em vista da raridade da apresentação clínica do adenoma pleomórfico nesta localização, os autores descrevem um caso de adenoma pleomórfico nasal em um paciente do sexo masculino, com 69 anos de idade, onde relatam os achados clínicos, critérios diagnósticos, tratamento, prognóstico e revisão da literatura.Nasal tumours are very rare. The neoplasms most frequently seen in the nasal cavity are epithelial papillomas, angiomas, transitional cells carcinoma, pavement carcinoma and adenocarcinoma. The pleomorphic adenoma belongs to the group of tumours less commonly observed in the nasal cavity, and is the most common head and neck benign glandular tumour. The typical clinical presentation of the nasal pleomorphic adenoma is of unilateral nasal obstruction, epistaxis and a painless mass in the nasal cavity. The authors reported an adenoma pleomorphic case that highlights itself by its unusual nasal presentation in the nasal septum of a 45-year-old male patient who was submitted to surgical treatment, and discuss the clinical findings, diagnostic criteria, treatment, prognosis and literature review.

  2. Fundus imaging with a nasal endoscope

    Directory of Open Access Journals (Sweden)

    P Mahesh Shanmugam

    2015-01-01

    Full Text Available Wide field fundus imaging is needed to diagnose, treat, and follow-up patients with retinal pathology. This is more applicable for pediatric patients as repeated evaluation is a challenge. The presently available imaging machines though provide high definition images, but carry the obvious disadvantages of either being costly or bulky or sometimes both, which limits its usage only to large centers. We hereby report a technique of fundus imaging using a nasal endoscope coupled with viscoelastic. A regular nasal endoscope with viscoelastic coupling was placed on the cornea to image the fundus of infants under general anesthesia. Wide angle fundus images of various fundus pathologies in infants could be obtained easily with readily available instruments and without the much financial investment for the institutes.

  3. Augmentation Rhinoplasty in Cleft Lip Nasal Deformity: Preliminary Patients’ Perspective

    Directory of Open Access Journals (Sweden)

    William H. C. Tiong

    2014-01-01

    Full Text Available The correction of cleft lip nasal deformity is challenging and there have been numerous methods described in the literature with little demonstrated technical superiority of one over another. The common clinical issues associated with cleft lip nasal deformity are its lack of symmetry, alar collapse on the affected side, obtuse nasal labial angle, short nasal length, loss of tip definition, and altered columella show among others. We carried out augmentation of cleft lip rhinoplasties with rib graft in 16 patients over the one-year study period. Each of these patients was reviewed and given questionnaire before and after surgery to evaluate their response on the outcome to the approach. Preoperatively, nasal asymmetry is the main complaint (14/16, 87.5% among our series of patients. Postoperatively, 12 (75% patients out of the 16 reported significant improvement in their nasal symmetry with the other four marginal. All patients reported excellent nasal projection postoperatively with good nasal tip definition. Our series of patients reported overall good satisfaction outcome and will recommend this procedure to other patients with cleft lip nasal deformity. In conclusion, augmentation of cleft lip rhinoplasty can be employed to achieve perceivable and satisfactory outcome in patients with cleft lip nasal deformity.

  4. Characterization of nasal cavity-associated lymphoid tissue in ducks.

    Science.gov (United States)

    Kang, Haihong; Yan, Mengfei; Yu, Qinghua; Yang, Qian

    2014-05-01

    The nasal mucosa is involved in immune defense, as it is the first barrier for pathogens entering the body through the respiratory tract. The nasal cavity-associated lymphoid tissue (NALT), which is found in the mucosa of the nasal cavity, is considered to be the main mucosal immune inductive site in the upper respiratory tract. NALT has been found in humans and many mammals, which contributes to local and systemic immune responses after intranasal vaccination. However, there are very few data on NALT in avian species, especially waterfowl. For this study, histological sections of the nasal cavities of Cherry Valley ducks were used to examine the anatomical location and histological characteristics of NALT. The results showed that several lymphoid aggregates are present in the ventral wall of the nasal cavity near the choanal cleft, whereas several more lymphoid aggregates were located on both sides of the nasal septum. In addition, randomly distributed intraepithelial lymphocytes and isolated lymphoid follicles were observed in the regio respiratoria of the nasal cavity. There were also a few lymphoid aggregates located in the lamina propria of the regio vestibularis, which was covered with a stratified squamous epithelium. This study focused on the anatomic and histological characteristics of the nasal cavity of the duck and performed a systemic overview of NALT. This will be beneficial for further understanding of immune mechanisms after nasal vaccination and the development of effective nasal vaccines for waterfowls. Copyright © 2014 Wiley Periodicals, Inc.

  5. Plasmocitoma extramedular nasal en un perro

    Directory of Open Access Journals (Sweden)

    Carlos Giraldo M.

    2012-12-01

    Full Text Available Se describe un caso de plasmocitoma nasal en un canino, macho entero, de raza Akita de 30 Kg de peso y veintiún meses de edad, con historia de epistaxis unilateral crónica. Se practicó examen clínico y biopsia de la neoplasia visible en la cavidad nasal izquierda. La ubicación y extensión del tumor fue determinada mediante tomografía computarizada de cabeza y cuello. Se realizaron análisis histopatológico e inmunohistoquímico (IHQ del tejido tumoral. La tomografía computarizada evidenció una masa con densidad de tejido blando de 10 cm de longitud x 3.5 cm de diámetro y escasa captación de medio de contraste, que comprometía en su totalidad la cavidad nasal derecha y parte de la porción posterior de la coana izquierda. El análisis histopatológico reveló numerosas células redondas pleomórficas con poco citoplasma, rodeadas por trama escasa de tejido conectivo y bajo índice mitótico. En el examen IHQ la muestra fue negativa a los antígenos CD3 y CD20 para linfocitos T y B, respectivamente. Los hallazgos clínicos y de la tomografía computarizada, así como los resultados del análisis histopatológico del tejido tumoral, fueron compatibles con un plasmocitoma extramedular nasal de bajo grado de malignidad.

  6. SEPTOPLASTY WITH AND WITHOUT NASAL PACKING: A COMPARATIVE STUDY

    Directory of Open Access Journals (Sweden)

    Mitta

    2016-05-01

    Full Text Available Septoplasty is one of the most commonly performed surgeries in rhinology to relieve nasal obstruction of patients with distortion in the midline cartilage or septum of the nose to relieve nasal obstruction of patient and findings consistent with nasal endoscopy. The anterior nasal packing routinely done following septoplasty is usually conventional and not evidence based. The purpose of nasal packing is to obtain haemostasis, enhance opposition of septal flaps, avoid septal haematoma formation, close the dead space, avoid synechiae formation, provide support to septal cartilage and prevent its displacement. OBJECTIVE This study intends to evaluate the effects of nasal packing on surgical success and related complications in septoplasty. MATERIALS AND METHODS The present clinical prospective and randomised study was carried out on patients attending Otorhinolaryngology Department of Santhiram Medical College & General Hospital between March 2012 and March 2015. Patients undergoing septoplasty were randomised either to receive anterior nasal packing or to not receive nasal packing postoperatively. RESULTS Levels of pain experienced by patients with nasal packing postoperatively during the initial 24 hours postoperatively and during the removal of the pack were significantly more. Post-operative headache, epiphora, swallowing discomfort and sleep disturbance were more in patients with nasal packing and statistically (p.05. Septal haematoma, adhesions and local infections in both groups were statistically insignificant (p>.05. CONCLUSION Septoplasty enhances the standard of living of patients with septal deviation and nasal obstruction. Our study results suggest that nasal packing after septoplasty is not obligatory. Nasal packing causes considerably more pain and complications, and it should be reserved only for those who have bleeding predisposition.

  7. Deformation of nasal septal cartilage during mastication.

    Science.gov (United States)

    Al Dayeh, Ayman A; Rafferty, Katherine L; Egbert, Mark; Herring, Susan W

    2009-10-01

    The cartilaginous nasal septum plays a major role in structural integrity and growth of the face, but its internal location has made physiologic study difficult. By surgically implanting transducers in 10 miniature pigs (Sus scrofa), we recorded in vivo strains generated in the nasal septum during mastication and masseter stimulation. The goals were (1) to determine whether the cartilage should be considered as a vertical strut supporting the nasal cavity and preventing its collapse, or as a damper of stresses generated during mastication and (2) to shed light on the overall pattern of snout deformation during mastication. Strains were recorded simultaneously at the septo-ethmoid junction and nasofrontal suture during mastication. A third location in the anterior part of the cartilage was added during masseter stimulation and manipulation. Contraction of jaw closing muscles during mastication was accompanied by anteroposterior compressive strains (around -1,000 muepsilon) in the septo-ethmoid junction. Both the orientation and the magnitude of the strain suggest that the septum does not act as a vertical strut but may act in absorbing loads generated during mastication. The results from masseter stimulation and manipulation further suggest that the masticatory strain pattern arises from a combination of dorsal bending and/or shearing and anteroposterior compression of the snout. 2009 Wiley-Liss, Inc.

  8. Nasal encephalocele: endoscopic excision with anesthetic consideration.

    Science.gov (United States)

    Abdel-Aziz, Mosaad; El-Bosraty, Hussam; Qotb, Mohamed; El-Hamamsy, Mostafa; El-Sonbaty, Mohamed; Abdel-Badie, Hazem; Zynabdeen, Mustapha

    2010-08-01

    Nasal encephalocele may presents as a nasal mass, its treatment is surgical and it should be done early in life. When removal is indicated, there are multiple surgical approaches; including lateral rhinotomy, a transnasal approach and a coronal flap approach. However, the treatment of a basal intranasal encephalocele using transnasal endoscopic approach could obviates the possible morbidity associated with other approaches. The aim of this study was to evaluate the efficacy of endoscopic removal of intranasal encephalocele, also to document the role of anesthetist in the operative and postoperative periods. Nine cases with nasal encephalocele were included in this study; CT and/or MRI were used in their examination. The lesions were removed via transnasal endoscopic approach. Preoperative evaluation, intervention and postoperative follow-up were presented with discussion of anesthesia used for those children. The lesions of all patients were removed successfully with no recurrence through the follow-up period of at least 21 months. No cases showed morbidity or mortality intra- or post-operatively. Endoscopic excision of intranasal encephalocele is an effective method with high success rate. Anesthetist plays an important role in the operative and postoperative period, even during the endoscopic follow up; sedation of the children is usually needed. Copyright (c) 2010 Elsevier Ireland Ltd. All rights reserved.

  9. Nasal nitric oxide in unilateral sinus disease.

    Directory of Open Access Journals (Sweden)

    Chia-Hsiang Fu

    Full Text Available Unilateral sinus disease (USD can sometimes be difficult to accurately diagnose before surgery. The application of nasal nitric oxide (nNO for USD diagnosis and its surgical outcome in USD has not been reported in the literature. We prospectively enrolled sixty-six USD patients who underwent endoscopic sinus surgery for fungal rhinosinusitis (n = 19, chronic rhinosinusitis (CRS without nasal polyps (n = 13, CRS with nasal polyps (n = 12 and sinonasal mass lesions (n = 22. nNO levels were measured preoperatively and at three and six months postoperatively. Correlations between nNO levels and potential clinical parameters, type of disease, disease severity, and disease-related quality of life (QOL were assessed. Unlike bilateral CRS, in USD, nNO levels did not correlate with disease severity or postoperative QOL improvements. Except for fungus group, there were no differences in nNO levels between lesion and non-lesion sides in all the other groups. nNO levels on both sides were significantly elevated six months postoperatively in all groups. Fungal rhinosinusitis patients had the lowest preoperative nNO levels, and a cutoff of 239.3 ppb had the best sensitivity (79.0% and specificity (87.2% for preoperative diagnosis. While preoperative nNO levels cannot serve as an alternative marker for disease severity of USD, they were lower in fungal rhinosinusitis patients than in other USD patients and may be useful for more accurate diagnosis prior to surgery.

  10. Nasal Foreign Bodies: A Sweet Experiment.

    Science.gov (United States)

    Leopard, D C; Williams, R G

    2015-10-01

    It is generally accepted that paediatric intranasal foreign bodies should be removed in the emergency setting. In the case of a difficult to access dissolvable foreign body in an uncooperative child, the question must be raised regarding whether or not a watch and wait strategy is more appropriate. We ask: How long does it take for popular sweets (candy) to dissolve in the human nose? Five popular UK sweets were placed in the right nasal cavity of a 29-year-old male (the author) with no sino-nasal disease. Time taken to dissolve was recorded. All five sweets were completely dissolved in under one hour. A watch and wait strategy in favour of examination under anaesthetic may be a viable option in some cases. Limitations of the study include the age of the participant and size of the sweets. It is also important in practice that the clinician is able to elicit an accurate history regarding the exact nature of the foreign body. It remains prudent to perform an examination under anaesthetic of an uncooperative child with a solid or unknown nasal foreign body. However, if the clinician can be certain the foreign body is a small sugar or chocolate based sweet only, a watch and wait strategy may be a reasonable choice. © 2015 John Wiley & Sons Ltd.

  11. Von Willebrand disease protects against arterial thrombosis

    NARCIS (Netherlands)

    Sanders, Y.V.; Eikenboom, J.C.; De Wee, E.M.; Van Der Bom, J.G.; Cnossen, M.H.; Degenaar-Dujardin, M.E.; Fijnvandraat, K.; Kamphuisen, P.W.; Laros-Van Gorkum, B.A.; Meijer, K.; Mauser -Bunschoten, E.P.; Leebee k, F.W.

    Background and Aims: Von Willebrand disease (VWD) is caused by reduced levels of or dysfunctional von Willebrand factor (VWF) and is characterized by a bleeding tendency. It is well known that individuals with high VWF levels have a higher risk for arterial thrombosis. Although it has never been

  12. Research, design and education, Von Humboldt revisited

    NARCIS (Netherlands)

    Bax, M.F.T.; Doevendans, C.H.; Trum, H.M.G.J.; Langenhuizen, Anja; Ouwerkerk, Marieke van; Rosemann, Jurgen

    2001-01-01

    This paper is a result of reflection on the interrelation design-research-cultivation, and on the interpretation of Von Humboldt's maxim: 'Einheit von Forschung und Lehre', which governed the academic world in the past two centuries. It is argued that 'Forschung' should be interpreted as 'Research

  13. Diffusion von Leerstelleninseln auf Cu(111)

    NARCIS (Netherlands)

    Verheij, Laurens K.; Schlößer, Dietmar; Rosenfeld, Georg

    1998-01-01

    Die zufällige Bewegung von Leerstelleninseln wurde bisher vorwiegend in einem Bild beschrieben, das von der Diffusion einzelner Atome ausgeht. In diesem Bild kann man Inseldiffusion durch die Einstein-Beziehung für Brownsche Bewegung ((Δ r)2 = 4 D Δ t) beschreiben. Für die Diffusionskonstante D wird

  14. Macromolecular contrast media. A new approach for characterising breast tumors with MR-mammography; Makromolekulare Kontrastmittel fuer die MR-Mammographie. Ein neuer Ansatz fuer die Charakterisierung von Mammatumoren

    Energy Technology Data Exchange (ETDEWEB)

    Daldrup, H.E. [Contrast Media Lab., Dept. of Radiology, California Univ., San Francisco, CA (United States)]|[Muenster Univ. (Germany). Inst. fuer Klinische Radiologie; Roberts, T.P.L.; Roberts, H.C. [Contrast Media Lab., Dept. of Radiology, California Univ., San Francisco, CA (United States)]|[Mainz Univ. (Germany). Klinik und Poliklinik fuer Radiologie; Muehler, A. [Contrast Media Lab., Dept. of Radiology, California Univ., San Francisco, CA (United States)]|[Berlex Laboratories, Wayne, NJ (United States); Gossmann, A. [Contrast Media Lab., Dept. of Radiology, California Univ., San Francisco, CA (United States)]|[Koeln Univ. (Germany). Inst. und Poliklinik fuer Radiologische Diagnostik; Wendland, M.; Brasch, R.C. [Muenster Univ. (Germany). Inst. fuer Klinische Radiologie; Rosenau, W. [California Univ., San Francisco, CA (United States). Dept. of Pathology

    1997-09-01

    The value of macromolecular contrast agents (MMCM) for the characterization of benign and malignant breast tumors will be demonstrated in this review. Animal studies suggest a high potential of MMCM to increase the specificity of MR-mammography. The concept of tumor differentiation is based on the pathological hyperpermeability of microvessels in malignant tumors. MMCM show a leak into the interstitium of carcinomas, whereas they are confined to the intravascular space in benign tumors. Capabilities and limitations of the MMCM-prototype. Albumin-Gd-DTPA, for breast tumor characterization will be summarized and compared to the standard low molecular weight contrast agent Gd-DTPA. Initial experience with new MMCM, such as Dendrimers, Gd-DTPA-Polylysine and MS-325 will be outlined. The potential of `blood-pool`-iron oxides, such as AMI-227 for the evaluation of tumor microvascular permeabilities will be discussed. (orig.) [Deutsch] Diese Uebersicht stellt den Stellenwert makromolekularer Kontrastmittel (MMKM) fuer die MR-tomographische Charakterisierung von benignen und malignen Mammatumoren dar. Aufgrund experimenteller Studien lassen MMKM eine signifikante Verbesserung der Spezifitaet der dynamischen kontrastmittelunterstuetzten MR-Mammographie erwarten. Das differentialdiagnostische Konzept beruht auf der pathologischen Hyperpermeabilitaet von Kapillaren in Karzinomen, die einen MMKM-Austritt in das Tumorinterstitium bedingt, waehrend die intakten Kapillaren benigner Tumoren nicht permeabel fuer MMKM sind. Diagnostische Moeglichkeiten und Grenzen des MMKM-Prototyps, Albumin-Gd-DTPA (92 kD), werden dargestellt und mit dem niedermolekularen Standard-Kontrastmittel Gd-DTPA (500 D) verglichen. Erste Erfahrungen mit neuen, fuer die klinische Anwendung optimierten MMKM-Praeparaten, wie das Kaskadenpolymer, Gd-DTPA-Polylysine und das MS-325 werden vorgestellt. Das Potential von Blood-pool-Eisenoxidpraeparaten, z.B. AMI-227, fuer die Bestimmung von

  15. Von Hippel-Lindau Disease

    Directory of Open Access Journals (Sweden)

    Hes Frederik J

    2005-11-01

    Full Text Available Abstract A germline mutation in the Von-Hippel Lindau (VHL gene predisposes carriers to development of abundantly vascularised tumours in the retina, cerebellum, spine, kidney, adrenal gland and pancreas. Most VHL patients die from the consequences of cerebellar haemangioblastoma or renal cell carcinoma. The VHL gene is a tumour suppressor gene and is involved in angiogenesis by regulation of the activity of hypoxia-inducible factor 1-α (HIF1-α. Clinical diagnosis of VHL can be confirmed by molecular genetic analysis of the VHL gene, which is informative in virtually all VHL families. A patient with (suspicion for VHL is an indication for genetic counselling and periodical examination.

  16. Analysis and chemometry of heavy metal concentrations in the Saale, Ilm and Unstrut as a basis for assessing the pollutant level and the prospects for success of sanitation measures. Final report; Analyse und chemometrische Bewertung von Schwermetallgehalten der Saale, Ilm und Unstrut als Bestandsaufnahme und zur Abschaetzung der Auswirkungen von Sanierungsmassnahmen. Abschlussbericht

    Energy Technology Data Exchange (ETDEWEB)

    Einax, J.W.; Truckenbrodt, D.; Kampe, O.

    1997-09-01

    Aspekten zu bewerten. Die Anwendung von Methoden der multivariaten Statistik ermoeglicht die Identifizierung anthropogener und geogener Quellen und die Aufdeckung latenter Zusammenhaenge. Damit ist eine umfassende Bewertung der tatsaechlichen Belastungssituation moeglich. (orig./SR)

  17. Exhaled and nasal nitric oxide in chronic rhinosinusitis patients with nasal polyps in primary care

    DEFF Research Database (Denmark)

    Frendø, M; Håkansson, K; Schwer, S

    2018-01-01

    BACKGROUND: Chronic rhinosinusitis with nasal polyps (CRSwNP) is a common inflammatory disorder associated with lower airway disease. However, only few studies of CRSwNP from outside secondary/tertiary care centres have been published. We recently reported an asthma frequency of 44% and 65...... patients. Compared with controls, a high level of exhaled NO was significantly more prevalent in CRSwNP irrespective of asthma-status. Nasal NO was significantly lower in patients with CRSwNP compared with controls. CONCLUSION: Subclinical eosinophilic lower airway inflammation is common in CRSwNP......% in primary and secondary care patients respectively. Therefore, we hypothesise that inflammation of the lower airways could be present in all CRSwNP patients, even without asthma. Here, we assessed the degree of lower and upper airway inflammation using exhaled and nasal nitric oxide (NO) in primary care...

  18. The Effect of Menstrual Cycle on Nasal Resonance Characteristics in Females

    Science.gov (United States)

    Kumar, Suman; Basu, Shriya; Sinha, Anisha; Chatterjee, Indranil

    2012-01-01

    The purpose of this study was to analyze resonance characteristics (nasality and nasalance values) during the menstrual cycle. Previous studies indicate changes in voice quality and nasal mucosa due to temporary falling estrogen levels in human females during their menstrual cycle. The present study compared the nasality and "nasalance scores"…

  19. Resident aerobic microbiota of the adult human nasal cavity

    DEFF Research Database (Denmark)

    Rasmussen, TT; Kirkeby Nielsen, LP; Poulsen, Knud

    2000-01-01

    Recent evidence strongly suggests that the microbiota of the nasal cavity plays a crucial role in determining the reaction patterns of the mucosal and systemic immune system. However, little is known about the normal microbiota of the nasal cavity. The purpose of this study was to determine...... the microbiota in different parts of the nasal cavity and to develop and evaluate methods for this purpose. Samples were collected from 10 healthy adults by nasal washes and by swabbing of the mucosa through a sterile introduction device. Both methods gave results that were quantitatively and qualitatively...... reproducible, and revealed significant differences in the density of the nasal microbiota between individuals. The study revealed absence of gram-negative bacteria that are regular members of the commensal microbiota of the pharynx. Likewise, viridans type streptococci were sparsely represented. The nasal...

  20. Kartagener's syndrome presented with nasal obstruction: A case report

    Directory of Open Access Journals (Sweden)

    Suna Asilsoy

    2014-08-01

    Full Text Available The nasal polyposis is a chronic inflammatory process of the nasal mucosa. Although it is rare in children, there may be also association with cystic fibrosis and primary ciliary dyskinesia. About 50% of primary ciliary dyskinesia patients develop situs inversus and it is known as Kartagener's syndrome. The Kartagener's sydrome is a rare autosomal recessive disorder characterized by sinusitis, bronchiectasis, situs inversus. Clinically, patients present to the otolaryngologist with nasal obstruction. We as pediatricians, should consider nasal polyposis as a rare cause of nasal obstruction in children. In the presence of recurrent upper and lower respiratory tract infections accompanying nasal polyposis, Kartagener's syndrome must be kept in mind as a rare reason. [Cukurova Med J 2014; 39(4.000: 942-945

  1. PET and SPECT investigations in Alzheimer's disease; Nuklearmedizin und Demenz - Anwendung bei Morbus Alzheimer

    Energy Technology Data Exchange (ETDEWEB)

    Asenbaum, S. [Universitaetsklinik fuer Nuklearmedizin, Universitaetsklinik fuer Neurologie, Wien (Austria); Abteilung fuer klinische Neurologie, Universitaetsklinik fuer Neurologie, Waehringer Guertel 18-20, 1090, Wien (Austria)

    2003-07-01

    Nuclear medicine offers a wide range of possibilities to investigate dementia. Various SPECT and PET tracers will be introduced in this article first. Different questions concerning evaluation of dementia are discussed taking Alzheimer's disease (AD) as an example. It is important to perform nuclear medicine investigations on high technical level, using standardized methods as statistical parametric mapping (SPM) for evaluation. If neuroprotective therapies are available, an early diagnosis, the determination of risk factors and longitudinal investigations will be the focus of interest and the main goal of nuclear medicine. Apart from measuring cerebral perfusion and glucose metabolism the development of new ligands, concerning the cholinergic system and the visualization of amyloid plaques, is of great importance. (orig.) [German] Nuklearmedizin bietet bei der Erfassung und Beurteilung eines dementiellen Prozesses eine Vielzahl von Untersuchungsmoeglichkeiten. Anhand des Morbus Alzheimer (DAT) werden in dem vorliegenden Artikel neben einer kurzen Schilderung der zur Verfuegung stehenden Methoden die verschiedenen nuklearmedizinisch relevante Fragestellungen angefuehrt, zu deren Beantwortung die funktionelle Bildgebung Informationen liefern kann. Durch den Einsatz bestimmter, standardisierter Auswerteverfahren wie statistical parametric mapping (SPM) ist es moeglich, entscheidende Hinweise zur Diagnose und Differenzialdiagnose der DAT zu erlangen. In Zukunft werden, insbesondere bei einer Verfuegbarkeit neuroprotektiver Therapien, eine moeglichst fruehe Diagnosestellung und die Erfassung von Risikofaktoren sowie die Moeglichkeit einer Verlaufsbeobachtung in den Mittelpunkt des Interesses und in das Zentrum nuklearmedizinischer Untersuchungen ruecken. Vor allem fuer diese Anforderungen ist neben der qualitaetsvollen Untersuchung von zerebraler Perfusion und Glukosestoffwechsel eine Weiterentwicklung spezieller Liganden v. a. das cholinerge System betreffend und

  2. Disposition of nasal, intravenous, and oral methadone in healthy volunteers.

    Science.gov (United States)

    Dale, Ola; Hoffer, Christine; Sheffels, Pamela; Kharasch, Evan D

    2002-11-01

    Nasal administration of many opioids demonstrates rapid uptake and fast onset of action. Nasal administration may be an alternative to intravenous and oral administration of methadone and was therefore studied in human volunteers. The study was approved by the Institutional Review Board of the University of Washington, Seattle. Eight healthy volunteers (6 men and 2 women) aged 19 to 33 years were enrolled after informed written consent was obtained. Subjects received 10 mg methadone hydrochloride nasally, orally, or intravenously on 3 separate occasions in a crossover design. Nasal methadone (50 mg/mL in aqueous solution) was given as a 100-microL spray in each nostril (Pfeiffer BiDose sprayer). Blood samples for liquid chromatography-mass spectrometry analyses of methadone and the metabolite 2-ethyl-1,5-dimethyl-3,3-diphenylpyrrolinium were drawn for up to 96 hours. The methadone effect was measured by noninvasive infrared pupilometry coincident with blood sampling. Nasal uptake of methadone was rapid, with maximum plasma concentrations occurring within 7 minutes. The maximum effects of intravenous, nasal, and oral methadone, on the basis of dark-adapted pupil diameter, were reached in about 15 minutes, 30 minutes, and 2 hours, respectively. The respective durations were 24, 10, and 8 hours. Both nasal and oral bioavailabilities were 0.85. Subjects reported that nasal methadone caused a burning sensation. Nasal administration of methadone results in rapid absorption and onset of effect and high bioavailability, which was greater than that reported for other nasal opioids, with a similar duration of effect. Nasal administration may be an alternative route of methadone administration; however, improved formulations are desirable to reduce nasal irritation.

  3. Nasal granuloma gravidarum presenting with recurrent massive epistaxis.

    Science.gov (United States)

    Tantinikorn, Weerachai; Uiprasertkul, Mongkol; Assanasen, Paraya

    2003-05-01

    Nasal granuloma gravidarum is a rare condition associated with pregnancy and minor trauma. This condition presents with a nasal mass with varying degree of bleeding and obstruction. We report a patient with nasal granuloma gravidarum in the third trimester of pregnancy. Surgical excision is the definite treatment for this condition in order to stop the vicious cycle of recurrent massive bleeding. Possible etiology, clinical features and management are discussed.

  4. Specificity and sensitivity assessment of selected nasal provocation testing techniques

    Directory of Open Access Journals (Sweden)

    Edyta Krzych-Fałta

    2016-12-01

    Full Text Available Introduction: Nasal provocation testing involves an allergen-specific local reaction of the nasal mucosa to the administered allergen. Aim: To determine the most objective nasal occlusion assessment technique that could be used in nasal provocation testing. Material and methods : A total of 60 subjects, including 30 patients diagnosed with allergy to common environmental allergens and 30 healthy subjects were enrolled into the study. The method used in the study was a nasal provocation test with an allergen, with a standard dose of a control solution and an allergen (5,000 SBU/ml administered using a calibrated atomizer into both nostrils at room temperature. Early-phase nasal mucosa response in the early phase of the allergic reaction was assessed via acoustic rhinometry, optical rhinometry, nitric oxide in nasal air, and tryptase levels in the nasal lavage fluid. Results : In estimating the homogeneity of the average values, the Levene’s test was used and receiver operating characteristic curves were plotted for all the methods used for assessing the nasal provocation test with an allergen. Statistically significant results were defined for p < 0.05. Of all the objective assessment techniques, the most sensitive and characteristic ones were the optical rhinometry techniques (specificity = 1, sensitivity = 1, AUC = 1, PPV = 1, NPV = 1. Conclusions : The techniques used showed significant differences between the group of patients with allergic rhinitis and the control group. Of all the objective assessment techniques, those most sensitive and characteristic were the optical rhinometry.

  5. Nasal septal angiofibroma, a subclass of extranasopharyngeal angiofibroma.

    Science.gov (United States)

    Garcia-Rodriguez, Laura; Rudman, Kelli; Cogbill, Christopher H; Loehrl, Todd; Poetker, David M

    2012-01-01

    Extranasopharyngeal angiofibromas (ENA) arising from the nasal septum or nasal septal angiofibromas are extremely rare; only 13 such cases have been reported in the international literature. Our objective is to describe the presentation, workup, and surgical management of these lesions. Case reports were done. The setting was a tertiary care referral center and the Veterans Affairs Medical Center. PATIENTS, INTERVENTIONS, AND RESULTS: We present 2 cases of extranasopharyngeal angiofibroma occurring on the nasal septum. In this report, we discuss the occurrence, the histopathologic findings, and the treatment of nasal septal angiofibroma. Copyright © 2012 Elsevier Inc. All rights reserved.

  6. Patient experience with mupirocin or povidone-iodine nasal decolonization.

    Science.gov (United States)

    Maslow, Jed; Hutzler, Lorraine; Cuff, Germaine; Rosenberg, Andrew; Phillips, Michael; Bosco, Joseph

    2014-06-01

    Led by the federal government, the payers of health care are enacting policies designed to base provider reimbursement on the quality of care they render. This study evaluated and compared patient experiences and satisfaction with nasal decolonization with either nasal povidone-iodine (PI) or nasal mupirocin ointment (MO). A total of 1903 patients were randomized to undergo preoperative nasal decolonization with either nasal MO or PI solution. All randomized patients were also given 2% chlorhexidine gluconate topical wipes. Patients were interviewed prior to discharge to assess adverse events and patient experience with their assigned preoperative antiseptic protocol. Of the 1903 randomized patients, 1679 (88.1%) were interviewed prior to discharge. Of patients receiving PI, 3.4% reported an unpleasant or very unpleasant experience, compared with 38.8% of those using nasal MO (P.05). Being recruited as an active participant in surgical site infection prevention was a positive experience for 87.2% of MO patients and 86.3% of PI patients (P=.652). Those assigned to receive PI solution preoperatively reported significantly fewer adverse events than the nasal MO group (P<.01). Preoperative nasal decolonization with either nasal PI or MO was considered somewhat or very helpful by more than two-thirds of patients. Copyright 2014, SLACK Incorporated.

  7. Nasal erosion as an uncommon sign of child abuse.

    Science.gov (United States)

    Culotta, Paige A; Isaac, Reena; Sarpong, Kwabena; Chandy, Binoy; Cruz, Andrea; Donaruma-Kwoh, Marcella

    2018-05-01

    While various forms of facial trauma, bruising, burns, and fractures are frequently seen in cases of child abuse, purposeful nasal erosion has rarely been identified as a form of abusive injury. Progressive destruction of nasal tissue in children provokes a wide differential diagnosis crossing multiple subspecialties: infectious, primary immunodeficiencies, inflammatory conditions, malignancy, and genetic disorders. Progressive nasal erosion also can be a manifestation of child abuse. The proposed mechanism is repetitive mechanical denudation of the soft tissue and cartilage resulting in chronic inflammation, bleeding, and ultimately destruction of the insulted tissue. We report 6 cases of child abuse manifesting as overt nasal destruction. Copyright © 2018 Elsevier B.V. All rights reserved.

  8. A Research of nasal methicillin resistant/sensitive Staphylococcus ...

    African Journals Online (AJOL)

    A Research of nasal methicillin resistant/sensitive Staphylococcus aureus and pharyngeal beta-haemolytic Streptococcus carriage in midwifery students in Kahramanmaras, Eastern Mediterranean Region of Turkey.

  9. Specifications for dumping of residues from mechanical-biological waste treament facilities; Anforderungen an die Ablagerung von MBA-Abfaellen

    Energy Technology Data Exchange (ETDEWEB)

    Bockreis, A.; Steinberg, I.; Jager, J. [Fachgebiet Afalltechnik, Institut WAR, TU Darmstadt (Germany)

    2001-07-01

    . Grundsaetzlich ist festzustellen, dass sich Schwierigkeiten bei der Anwendung und Umsetzung der Vorschriften der AbfAblV ergeben. Dies aeussert sich zum Einen in der Haeufigkeit der Durchfuehrung der Analysen und zum Anderen in der Einhaltung der Grenzwerte der Zuordnungskriterien. Die Forderungen nach einer eingehenden Ueberpruefung und Ueberarbeitung der Methodenvorschriften fuer AT{sub 4} und GB 21 sowie deren Zuordnungswerte in Zusammenhang mit den Zuordnungswerten von TOC, sowohl im Feststoff als auch im Eluat, und dem Heizwert H{sub 0} nach weiteren praktischen Erfahrungen werden als notwendig angesehen. (orig.)

  10. Investigations of co-combustion of plastics in a coal dust furnace; Untersuchungen zur Mitverbrennung von Kunststoffen in einer Kohlestaubfeuerung

    Energy Technology Data Exchange (ETDEWEB)

    Gerhardt, T.; Spliethoff, H.; Hein, K.R.G. [Stuttgart Univ. (Germany). Inst. fuer Verfahrenstechnik und Dampfkesselwesen (IVD); Christill, M.; Kicherer, A.; Seifert, H. [BASF AG, Verfahrenstechnik-ZET/EH-L544, Ludwigshafen am Rhein (Germany)

    1996-12-31

    schwer entzuendlichen Materials, konnte fuer die IVD-Versuchsbrennkammer in Grenzkornspektrum von 1,25 bis 1,5 mm Partikelgroesse, bei der Verbrennung mit Steinkohle, erreicht werden. Fuer die industrielle Anwendung werden durch die andere Brenneranordnung eher bessere Resultate gegenueber der Versuchsanlage erwartet. (orig)

  11. Investigations of co-combustion of plastics in a coal dust furnace; Untersuchungen zur Mitverbrennung von Kunststoffen in einer Kohlestaubfeuerung

    Energy Technology Data Exchange (ETDEWEB)

    Gerhardt, T; Spliethoff, H; Hein, K R.G. [Stuttgart Univ. (Germany). Inst. fuer Verfahrenstechnik und Dampfkesselwesen (IVD); Christill, M; Kicherer, A; Seifert, H [BASF AG, Verfahrenstechnik-ZET/EH-L544, Ludwigshafen am Rhein (Germany)

    1997-12-31

    schwer entzuendlichen Materials, konnte fuer die IVD-Versuchsbrennkammer in Grenzkornspektrum von 1,25 bis 1,5 mm Partikelgroesse, bei der Verbrennung mit Steinkohle, erreicht werden. Fuer die industrielle Anwendung werden durch die andere Brenneranordnung eher bessere Resultate gegenueber der Versuchsanlage erwartet. (orig)

  12. Jacob Stael von Holstein ja palladionism eesti arhitektuuris / Ants Hein

    Index Scriptorium Estoniae

    Hein, Ants, 1952-

    2005-01-01

    Sõjaväeinsenerist ja arhitektist Jacob Stael von Holsteinist (1628, Pärnu-1679), tema kavandatud hoonetest ja rollist 17. sajandi II poole arhitektuuris. Fabian von Ferseni Toompeal Lossiplatsil asunud elamust (lammutati 1894) ja Maardu mõisahoonest, Hans von Ferseni Mäo mõisahoonest Järvamaal, Otto Wilhelm von Ferseni majast Toompeal, Axel von Roseni majast Tallinnas Pikk t. 28 (1670-74), Otto Reinhold von Taube majast Tartus (hävinud), J. S. von Holsteini enda hoonetest: majast Tallinnas Toompea 1, Anija mõisahoonest, elamust Riias jm. Bibliograafia lk. 452

  13. The von Meyenburg complex; Der von Meyenburg Komplex

    Energy Technology Data Exchange (ETDEWEB)

    Schwab, S.A.; Bautz, W.; Uder, M.; Kuefner, M.A. [Erlangen-Nuernberg Univ., Erlangen (Germany). Inst. fuer Radiologie

    2008-07-01

    The von Meyenburg complex (VMC) describes bile duct hamartomas and presents a rare, benign incidental finding in liver imaging. We report on a 61-year-old man, who was referred for a follow up study 14 years after remission of Hodgkin's disease. Computed tomography (CT) revealed multiple hypodense lesions throughout the liver, primary suggesting recurrent Hodgkin's disease. Previous CT-examinations, which were obtained at a later date, showed those lesions in identical distribution and morphology over the years, leading to diagnosis of multiple bile duct hamartomas (VMC). Making imaging-based diagnosis of VMC including ultrasound, CT and magnetic resonance imaging is a challenging task for the radiologist. Based on literature research findings, the impact of different modalities in the diagnostic work-up of VMC is discussed. (orig.)

  14. Neues über das Tertiär von Java und die mesozoischen Schichten von West-Borneo

    NARCIS (Netherlands)

    Martin, K.

    1888-01-01

    Die Monographie, welche unter dem Titel Die Fossilien von Java herausgegeben wird ¹), ist so weit fortgeschritten, dass sich aus den in ihr beschriebenen Gastropoden bereits eine Anzahl von Schlussfolgerungen ableiten lässt, welche für die in Bearbeitung begriffene, geologische Karte von Java von

  15. Siebenjährige Follow-up-Studie zur Anwendung des spannungsfreien Vaginalbandes (TVT zur Behandlung der Stressharninkontinenz

    Directory of Open Access Journals (Sweden)

    Nilsson CG

    2005-01-01

    Full Text Available Studienzweck: Evaluierung der langfristigen Heilungs- und Spätkomplikationsraten bei Stressharninkontinenz der Frau bei Behandlung mit dem spannungsfreien Vaginalband (TVT, das anhand einer minimal-invasiven Operation eingesetzt wird. Methodik: In drei Studienzentren durchgeführte prospektive Beobachtungs- und Kohortenstudie mit ursprünglich 90 Frauen, deren primäre Stressharninkontinenz einen operativen Eingriff erforderlich machte. Zu den Bewertungsvariablen gehörten ein Vorlagentest (Pad-Test zur Messung des Uringewichts je 24 Stunden, ein Stresstest, eine visuelle Analogskala (VAS zur Beurteilung des Beschwerdegrads sowie ein Fragebogen zur Beurteilung der subjektiven Wahrnehmung des Kontinenzstatus durch die Frauen. Ergebnisse: Als Follow-up-Zeitraum wurde ein durchschnittlicher Zeitraum von 91 Monaten (78–100 Monate festgelegt. Sowohl die objektive als auch die subjektive Heilungsrate lag bei den an der Follow-up-Studie teilnehmenden 80 Frauen bei 81,3 %. Bei 7,8 % der Frauen wurde ein asymptomatischer Prolaps der Organe des kleinen Beckens, bei 6,3 % De-novo-Drangsymptome und bei 7,5 % eine rezidivierende Harnwegsinfektion festgestellt. Weitere unerwünschte Nebenwirkungen des Verfahrens wurden nicht festgestellt. Schlussfolgerung: Die Wirkung der TVT-Operation zur Behandlung der Stressharninkontinenz der Frau bleibt über einen Zeitraum von 7 Jahren erhalten.

  16. The effect of nasalization on /a/ vowel formants before and after nasal consonant in 4-9-year old normal Persian speaking children

    Directory of Open Access Journals (Sweden)

    Kowsar Baghban

    2014-01-01

    Full Text Available Background and Aim : Nasalization of a vowel refers to the addition of nasal resonance to the vocal tract transfer function. Also, vowel nasalization occurs because of coarticulation. Coupling of the nasal resonating space to the oropharyngeal cavity alters the vocal tract formants in complex ways. The purpose of this study was to investigate the effect of nasalization on /a/ vowel formants in before and after nasal consonant.Methods: In current cross-sectional study, voice samples of 60 normal children ranging the age of four-nine years were investigated. Participants were asked to repeat / ʔ ama/ three times and vowel /a/ after presentation of an auditory model. Then, obtained samples were analyzed using Praat 5.3.13 . Average of F0, F1, F2 and F3 were calculated for /a/ comes before and after /m/ in production of / ʔ ama/ over three trials.Results: There were statistically significant differences of F1, F2 and F3 between / a/ which proceeds nasal consonant and /a/ follows nasal consonant , the before nasal consonant /a/ versus single /a/ and the after nasal consonant /a/ versus single /a/ (p=0.001 for all.Conclusion : F1, F2 and F3 in /a/ before nasal consonant affected by anticipatory nasal coarticulation and in /a/ after nasal consonant affected by carry-over nasal coarticulation . This study showed nasal coarticulation and nasalization result in decreasing F1, F2 and F3 in /a/ vowel.

  17. Relevance of histamine and tryptase concentrations in nasal secretions after nasal challenges with phosphate buffered saline and allergen

    Directory of Open Access Journals (Sweden)

    D. Wang

    1995-01-01

    Full Text Available In this prospective study, a quantitative determination of histamine and tryptase in nasal secretions after nasal phosphate buffered saline (PBS and allergen challenge was performed in 18 atopic patients who were compared with ten non-allergic healthy volunteers. The aim of the study was to determine the normal and pathological concentrations of these important mediators in nasal secretions. The second objective was to test the relevance of these two mast cell secreted mediators after nasal challenge. Results showed that the concentrations of tryptase in almost all samples were under the minimal detection limit (< 0.5 μU/g and only a sigrtificant increase of tryptase (median, 28 μU/g occurred immediately after nasal allergen challenge in the patient group. Histamine concentration significantly increased after every nasal PBS challenge (median, 69 ng/g after first PBS challenge and 165 ng/g after second PBS challenge in the control group, as well as in the patient group after both PBS (median, 69 ng/g and allergen (median, 214 ng/g challenge. On the other hand, a rapid onset of sneezing and increase in nasal airway resistance was experienced only in the patient group after nasal allergen challenge, but did not occur after PBS challenge even though the histamine concentrations significantly increased in both groups. This study suggests that tryptase is a more preferable marker than histamine in quantitative monitoring of mast cell activation especially during the early phase nasal allergic reaction.

  18. Randomized trial of prongs or mask for nasal continuous positive airway pressure in preterm infants.

    LENUS (Irish Health Repository)

    Kieran, Emily A

    2012-11-01

    To determine whether nasal continuous positive airway pressure (NCPAP) given with nasal prongs compared with nasal mask reduces the rate of intubation and mechanical ventilation in preterm infants within 72 hours of starting therapy.

  19. Presurgical Nasal Molding With a Nasal Spring in Patients With Mild-to-Moderate Nasal Deformity With Incomplete Unilateral Cleft Lip With or Without Cleft Palate.

    Science.gov (United States)

    Peanchitlertkajorn, Supakit

    2018-01-01

    Traditional nasoalveolar molding (NAM) requires steep learning curve for clinicians and significant compliance from parents. Nasal springs have been developed by the author to simplify presurgical nasal molding. This article presents the design, construction, and application of the spring. The treatment goal is to improve nasal deformity prior to primary repair in infants born with incomplete unilateral cleft lip with or without cleft palate. The design, fabrication, and utility of the nasal spring are described. The spring has a simpler design and construction compared to a traditional NAM appliance. Two patients with incomplete unilateral cleft lip with and without cleft palate are presented. The spring is constructed and delivered. The active arm of the spring can be 3-dimensionally (3-D) adjusted to mold the alar cartilage of the affected nostril. The spring does not require an oral plate for adherence as a traditional NAM appliance does, hence an oral impression is not needed. The spring is easy for clinicians to adjust. It also requires less compliance by parents. Main Outcome Measures/Results: The presurgical molding achieved by the use of a nasal spring improved surgical nasolabial aesthetic outcomes. The nasal springs are effective in reducing the initial cleft nasal deformity. This facilitates primary surgical cleft lip and nose correction and improves surgical outcomes in patients with incomplete unilateral cleft lip with or without cleft palate.

  20. Xanthomatose normolipidemique a localisation nasale chez une ...

    African Journals Online (AJOL)

    Introduction : Exposer un cas de xanthomatose normolipidémique. Observation : il s'agit d'une adolescente de 18 ans qui a présenté une masse des cavités nasales dont le bilan paraclinique a plaidé en faveur d'un xanthogranulome juvénile. L'évolution à court terme a été satisfaisante après l'exérèse chirurgicale par une ...

  1. Eine Analyse des Zusammenhangs zwischen dem Konsum von Alkopops und dem Problemverhalten von Jugendlichen

    OpenAIRE

    Metzner, Cornelia Beate Isabel

    2007-01-01

    Zielsetzung: In dieser Arbeit wird untersucht, ob bei Jugendlichen ein Zusammenhang zwischen dem Konsum von Alkopops einerseits und dem sonstigen Alkoholtrinkverhalten, dem Konsum von Zigaretten und illegalen Drogen sowie weiteren Risikoverhaltensweisen andererseits besteht, ferner ob sich Unterschiede im Verhalten von Jungen und Mädchen ergeben. Theoretischer und empirischer Hintergrund: �Alkopops�, d. h. Mischgetränke diverser Hersteller aus Likör bzw. Schnaps und Limonade sowie wein- ...

  2. Analytik von Minorlipiden: Ferulasäureester von Phytosterolen (gamma-Oryzanol) in Reis

    OpenAIRE

    Miller, Andreas

    2005-01-01

    Ferulasäureestern von Phytosterolen (γ-Oryzanol) werden antioxidative und cholesterinsenkende Eigenschaften zugeschrieben. Bisher beschriebene Methoden zur Analytik von γ-Oryzanol in Reis erforderten eine aufwendige Aufreinigung des Probenextrakts. In dieser Arbeit wurde basierend auf der on-line LC-GC eine Methode entwickelt, die die simultane Bestimmung von γ-Oryzanol-Gehalt und Sterylferulat-Verteilung ohne Aufreinigung des Probenextrakts erlaubt. Mit Hilfe der Technik wurden die natürlich...

  3. Redoxspeziation von endlagerrelevanten Elementen mit Hilfe von Trennmethoden gekoppelt an ein Massenspektrometer mit induktiv gekoppeltem Plasma

    OpenAIRE

    Graser, Carl-Heinrich

    2015-01-01

    Im Rahmen dieser Arbeit wurden Redoxspeziationsanalysen von Eisen, Neptunium und Plutonium per CE-SF-ICP-MS durchgeführt. Durch Optimierung der Trennparameter konnten Trennungen der Pu Oxidationsstufen III bis VI und Trennungen der Np Oxidationsstufen IV bis VI binnen 15 Minuten mit einer Nachweisgrenze von 10-12 M durchgeführt werden. Die Trennung der Fe Oxidationsstufen II und III gelang in weniger als 5 Minuten mit einer Nachweisgrenze von 5-10-8 M.

  4. THE DIGITAL VON FAHRENHEID PYRAMID

    Directory of Open Access Journals (Sweden)

    M. Bura

    2017-08-01

    Full Text Available 3D Scanners Lab from Digital Humanities Laboratory at the University of Warsaw initiated the scientific project, the purpose of which was to call attention to systematically penetrated and devastated pyramid-shaped tomb from the XVIII/XIX century, of family von Fahrenheid in Rapa in Banie Mazurskie commune (NE Poland. By conducting a series of non-invasive studies, such as 3D inventory using terrestrial laser scanning (TLS, thermal imaging, georadar measurements (around and inside the tomb and anthropological research of mummified remains as well - the complete dataset was collected. Through the integration of terrestrial (TLS and airborne laser scanning (ALS authors managed to analyse the surroundings of Fahrenheid pyriamid and influence of some objects (like trees on the condition and visibility of the Pyramids in the landscape.

  5. Die Wirkung von Desacetylcefotaxin, einem Metaboliten von Cefotaxim, in vitro und auf die experimentelle Infektion mit Escherichia coli

    OpenAIRE

    Wirbelauer, J.; Hof, H.; Hacker, Jörg

    2009-01-01

    Die MHK-Werte von Desacetylcefotaxim gegen verschiedene, z. T. ampicillinresistente Stämme von Escherichia coH, die mit Hilfe einer Agardilutionsmethode erhoben wurden, waren höher als die von Cefotaxim und Ceftriaxon, jedoch niedriger als die von Cefoxitin. In einem Modell der systemischen Infektion der Maus mit einem plasmidtragenden, betalactamaseproduzierenden Stamm von E. coli führte die Therapie mit Desacetylcefotaxim zu einer starken Reduktion der Keime pro Leber. Im Vergleich zur Ther...

  6. Subjective Evaluation of Vocal Quality in Nasal Polyposis

    Directory of Open Access Journals (Sweden)

    Ziya Saltürk

    2014-12-01

    Full Text Available Aim: Nose is a resonator organ in production of voice. The aim of this study was to evaluate the effects of nasal obstruction caused by nasal polyposis on voice quality subjectively. Methods: Thirty-six patients diagnosed with nasal polyposis were included in the study. The 30-item voice handicap index 30 was used in order to evaluate subjective status of voice. Nasal endoscopy and computed tomography imaging of the paranasal sinuses were performed for each patient. Lund-Kennedy endoscopy scores and Lund-MacKay computed tomography scores were evaluated. Control group composed of 20 healthy subjects. Results: The mean voice handicap score in the patient group was 43.16 (SD 15.53 and it was 2.15 (SD 1.92 in control group. There was a statistically significant difference between the groups (p=0.001. The mean Lund-Kennedy and Lund-Mackay scores were 8.58 (SD 2.5 and 17 (SD 5.52, respectively. It was found that increased severity of nasal polyposis was the cause for decreased satisfaction with voice quality. Conclusion: Nasal obstruction caused by nasal polyposis affects voice quality adversely and as the severity of nasal polyposis increases, satisfaction with voice quality decreases.

  7. The effect of nasal surgery on apnea-hypopnea index

    Directory of Open Access Journals (Sweden)

    Navid Nourizadeh

    2014-04-01

    Full Text Available One of the factors, which is involved in obstructive sleep apnea, is anatomic or inflammatory pathologies of nasal airway obstruction. Thus, it is logical to observe improvement of polysomnographic parameters of sleep-disordered breathing after nasal surgery. The authors performed a review of the literature, up to 2013, to determine the impact of nasal surgery on obstructive sleep apnea. Most current idea in this field is based on case series studies while randomized controlled trials evaluating the effect of surgery for nasal obstruction on sleep apnea are few and far between. According to these studies, surgery for nasal obstruction does not improve objective parameters of sleep apnea. Although nasal obstruction is one of the factors involved in obstructive apnea, one has to keep in mind that surgery will not result in major reduction of obstructive sleep apnea severity to relieve nasal obstruction. Detailed upper airway analysis has to be considered when surgery is an option for obstructive sleep apnea. Thus, nasal surgeries are beneficial when they are part of a multilevel approach in obstructive sleep apnea treatment.

  8. A study of Staphylococcus aureus nasal carriage, antibacterial ...

    African Journals Online (AJOL)

    Aim: This study was to determine the virulence encoding genes, and the antibiotic resistance patterns of the Staphylococcus aureus isolates, which were isolated from the nasal samples of chest clinic patients. Materials and Methods: The nasal samples of the in‑patients (431) and out‑patients (1857) in Kayseri Training and ...

  9. Nasal cytochrome P4502A: Identification in rats and humans

    Energy Technology Data Exchange (ETDEWEB)

    Thornton-Manning, J.R.; Hotchkiss, J.A. [Michigan State Univ., East Lansing, MI (United States); Ding, Xinxin [Wadsworth Center for Laboratories and Research, Albany, NY (United States)] [and others

    1995-12-01

    The nasal mucosa, the first tissue of contact for inhaled xenobiotics, possesses substantial enobiotic-metabolizing capacti. Enzymes of the nasal cavity may metabolize xenobiotics to innocuous, more water-soluble compounds that are eliminated from the body, or they may bioactivate them to toxic metabolites. These toxic metabolites may find to cellular macromolecules in the nasal cavity or be transported to other parts of the body where they may react. Nasal carcinogenesis in rodents often results from bioactivation of xenobiotics. The increased incidences of nasal tumors associated with certain occupations suggest that xenobiotic bioactivation may be important in human nasal cancer etiology, as well. The increasing popularity of the nose as a route of drug administration makes information concerning nasal drug metabolism and disposition vital to accomplish therapeutic goals. For these reasons, the study of xenobiotic-met abolizing capacity of the nasal cavity is an important area of health-related research. In the present study, we have confirmed the presence of CYP2A6 mRNA in human respiratory mucosa.

  10. Nasal Chondromesenchymal Hamartoma: CT and MR Imaging Findings

    International Nuclear Information System (INIS)

    Kim, Ji Eun; Kim, Hyung Jin; Kim, Ji Hye; Ko, Young Hyeh; Chung, Seung Kyu

    2009-01-01

    We report CT and MR imaging findings for a case of nasal chondromesenchymal hamartoma occurring in a 19-month-old boy. A nasal chondromesenchymal hamartoma is a rare benign pediatric hamartoma that can simulate malignancy. Although rare, knowledge of this entity is essential to avoid potentially harmful therapies

  11. The development of the nasal capsule of the silver carp ...

    African Journals Online (AJOL)

    The development of the nasal capsule, including the procartilaginous as well as some mesenchymatous developmental stages, is described in the chinese silver carp,. Hypophthalmichthys molitrix (VaL). In the nasal capsule a primitive feature, namely the presence of a complete paraphysial bridge was observed.

  12. Systematic review: the influence of nasal obstruction on sleep apnea

    Directory of Open Access Journals (Sweden)

    Debora Petrungaro Migueis

    2016-04-01

    Full Text Available ABSTRACT INTRODUCTION: Obstructive sleep apnea syndrome (OSAS is a common disorder that can lead to cardiovascular morbidity and mortality, as well as to metabolic, neurological, and behavioral consequences. It is currently believed that nasal obstruction compromises the quality of sleep when it results in breathing disorders and fragmentation of sleep. However, recent studies have failed to objectively associate sleep quality and nasal obstruction. OBJECTIVE: The aim of this systematic review is to evaluate the influence of nasal obstruction on OSAS and polysomnographic indices associated with respiratory events. METHODS: Eleven original articles published from 2003 to 2013 were selected, which addressed surgical and non-surgical treatment for nasal obstruction, performing polysomnography type 1 before and after the intervention. RESULTS/CONCLUSIONS: In most trials, nasal obstruction was not related to the apnea-hypopnea index (AHI, indicating no improvement in OSAS with reduction in nasal resistance. However, few researchers evaluated other polysomnography indices, such as the arousal index and rapid eye movement (REM sleep percentage. These could change with nasal obstruction, since it is possible that the nasal obstruction does not completely block the upper airways, but can increase negative intrathoracic pressure, leading to sleep fragmentation.

  13. Significance of computerized tomography and nasal cytology in the ...

    African Journals Online (AJOL)

    Ehab

    assessment of sinus disease in asthmatic children. Rhinosinusitis is a common asthma comorbidity. Nasal eosinophil or neutrophil score >0.5 provides a better predictive value for rhinosinusitis compared to total serum IgE. Keywords: computerized tomography, nasal sinus, asthma, sinusitis, allergic rhinitis, children.

  14. The validity of nasal endoscopy in patients with chronic rhinosinusitis

    DEFF Research Database (Denmark)

    Larsen, K. L.; Lange, B.; Darling, P.

    2018-01-01

    Objectives: Nasal endoscopy is a cornerstone in diagnosing sinonasal disease, but different raters might generate different results using the technique. Our study aims to evaluate the agreement between multiple raters to assess the validity of nasal endoscopy. Design/Participants: Three independe...

  15. Computed tomographic anatomy of the canine nasal passages

    International Nuclear Information System (INIS)

    Burk, R.L.

    1992-01-01

    A normal German shepherd dog underwent CT imaging with contiguous 10 mm thick images made of the nasal cavity from the caudal limit of the frontal sinuses to the rostral aspect of the nose. Normal structures were identified. This normal anatomic information will be of use in assessing CT images of dogs suspected of having nasal cavity disease

  16. Systematic review: the influence of nasal obstruction on sleep apnea.

    Science.gov (United States)

    Migueis, Debora Petrungaro; Thuler, Luiz Claudio Santos; Lemes, Lucas Neves de Andrade; Moreira, Chirlene Santos Souza; Joffily, Lucia; Araujo-Melo, Maria Helena de

    2016-01-01

    Obstructive sleep apnea syndrome (OSAS) is a common disorder that can lead to cardiovascular morbidity and mortality, as well as to metabolic, neurological, and behavioral consequences. It is currently believed that nasal obstruction compromises the quality of sleep when it results in breathing disorders and fragmentation of sleep. However, recent studies have failed to objectively associate sleep quality and nasal obstruction. The aim of this systematic review is to evaluate the influence of nasal obstruction on OSAS and polysomnographic indices associated with respiratory events. Eleven original articles published from 2003 to 2013 were selected, which addressed surgical and non-surgical treatment for nasal obstruction, performing polysomnography type 1 before and after the intervention. In most trials, nasal obstruction was not related to the apnea-hypopnea index (AHI), indicating no improvement in OSAS with reduction in nasal resistance. However, few researchers evaluated other polysomnography indices, such as the arousal index and rapid eye movement (REM) sleep percentage. These could change with nasal obstruction, since it is possible that the nasal obstruction does not completely block the upper airways, but can increase negative intrathoracic pressure, leading to sleep fragmentation. Copyright © 2015 Associação Brasileira de Otorrinolaringologia e Cirurgia Cérvico-Facial. Published by Elsevier Editora Ltda. All rights reserved.

  17. Nasal cavity of the farmed african catfish Clarias gariepinus ...

    African Journals Online (AJOL)

    The nasal cavity microanatomy of farmed fingerlings of African catfish, Clarias gariepunus was investigated to fill existing knowledge gap on its histology from available literatures. This becomes very important as no gustatory cell was reported from previous researches on the fingerling digestive tract. A slice of nasal cavity of ...

  18. VON WISPR Family Processors: Volume 1

    National Research Council Canada - National Science Library

    Wagstaff, Ronald

    1997-01-01

    ...) and the background noise they are embedded in. Processors utilizing those fluctuations such as the von WISPR Family Processors discussed herein, are methods or algorithms that preferentially attenuate the fluctuating signals and noise...

  19. Von Onlineplattformen und mittelalterlichen Märkten

    Directory of Open Access Journals (Sweden)

    Claudius Gräbner

    2017-12-01

    Full Text Available Mit der zunehmenden Digitalisierung und Vernetzung ökonomischer Systeme haben plattformbasierte Interaktionsbeziehungen stark an Bedeutung gewonnen. Hier werden zwei oder mehr Nutzungsgruppen durch eine dritte Seite, die Plattform, zusammengebracht. Die Interaktion wird in solchen zweiseitigen Märkten von den Plattformbetreibern kontrolliert. Kreditkartensysteme, Softwaremärkte oder werbefinanzierte Online-Communities stellen typische Beispiele dar. Da die Analyse von zweiseitigen Märkten mit Gleichgewichtsmodellen aufgrund der algebraischen Struktur des Problems in der Regel nicht praktikabel ist, präsentieren wir im vorliegenden Beitrag ein agentenbasiertes Modell, welches in einem kürzlich erschienenen Artikel ausführlicher diskutiert wird. Anhand von illustrativen Beispielen verdeutlichen wir die Implikationen eines agentenbasierten Ansatzes für die Innovationsökonomik im Allgemeinen und das Studium von Technologieentwicklung im Besonderen.

  20. Johann Friedrich Wilhelm Adolf von Baeyer

    Indian Academy of Sciences (India)

    Home; Journals; Resonance – Journal of Science Education; Volume 19; Issue 6. Johann Friedrich Wilhelm Adolf von Baeyer: A Pioneer of Synthetic Organic Chemistry. Gopalpur Nagendrappa. General Article Volume 19 Issue 6 June 2014 pp 489-522 ...

  1. Nasal polyps. A clinical radiological histopathological and mycological study

    Energy Technology Data Exchange (ETDEWEB)

    Babiker, Babiker Eltayeb [Faculty of Medicine, University of Khartoum, Khartoum (Sudan)

    1997-12-01

    Forty patients with nasal polyposis were studied. This study included clinical, haematological and mycological aspects. There were 24 females (60% of patients) and 16 males (40%). We found that all patients presented with nasal obstruction and nasal tone and the majority of them had allergic nasal symptoms such as sneezing and watery discharge. Thirty five percent of the patients were recurrent cases, being operated before for nasal polyps. Radiological investigations showed high of sinusitis and that 10% of the patients had complicated disease with orbital or intracranial extensions. Mycological studies revealed the presence of fungal infection in 4 patient (10%) and it was caused by Aspergillus flavus. Histological studies identified the allergic nature of the polyps in all patients. Surgical treatment was carried out in all patients and operations varied from simple intranasal polypectomy, intranasal ethmiodectomy, external ethmoidectomy to Caldwell-Luc operation for patients with antrochanal polyps.(Author)

  2. Capillary hemangioma of adult nasal cavity: a case report

    International Nuclear Information System (INIS)

    Paik, Sang Hyun; Kim, Hyun Sook; Kim, Wan Seop; Cho, Sung Bum; Choi, Yun Sun; Chung, Myung Jin; Kim, Seog Joon; Yoon, Sook Ja; Yoon, Yong Kyu

    2002-01-01

    Capillary hemangioma of the adult nasal cavity is rare. We report a case which occurred in the right nasal cavity of a 25-year-old woman, together with the multiphase enhanced CT findings. The patients who had a history of recurrent nasal bleeding, had experienced nasal obstruction and swelling during the two-month period prior to presentation, and one month before presentation, spontaneous vaginal delivery occurred. Physical examination revealed the presence of a well-defined round mass, with redness in the right nasal vertibule. The mass showed rim enhancement at early arterial-phase CT scanning, increased enhancement at the late arterial phase, and moderately homogeneous enhancement at the delayed phase

  3. Correlation of nasal geometry with aerosol deposition in human volunteers

    International Nuclear Information System (INIS)

    Cheng, Yung-Seng; Simpson, S.Q.; Cheng, Kuo-His; Swift, D.L.; Yeh, Hsu-Chi; Guilmette, R.A.

    1994-01-01

    The nasal airways act as the first filter in the respiratory tract to remove very large or small particles, that would otherwise penetrate to the lower airways. Aerosol deposition data obtained with human volunteers vary considerably under comparable experimental conditions. Reasons for the intersubject variations have been frequently attributed to the geometry of the nasal passages. Because there is no direct proof of this hypothesis, nasal deposition of ultrafine particles in human volunteers has been studied in our laboratory. Preliminary results obtained with four adult volunteers also vary considerably between subjects. The purpose of this part of the study was to establish a theoretical equation relating diffusional deposition in nasal airways to the geometrical dimensions of the individual nasal airways. This relationship was then applied to the experimental deposition data and measurement of airway morphometry for correlation

  4. A Case of Nasal Glial Heterotopia in an Adult

    Directory of Open Access Journals (Sweden)

    Akira Hagiwara

    2014-01-01

    Full Text Available We report a rare case of nasal glial heterotopia in an adult. After the surgery, frontal lobe cerebral hemorrhage developed. A 58-year-old man had unilateral nasal obstruction that progressed for one year. He had been treated for hypertension, chronic heart failure, and cerebral infarction with aspirin and warfarin. A computed tomography scan showed that the tumor occupied the right nasal cavity and the sinuses with small defect in the cribriform plate. The tumor was removed totally with endoscopy. After the operation, the patient developed convulsions and frontal lobe cerebral hemorrhage. The hemorrhage site was located near a defect in the cribriform plate. Nasal glial heterotopia is a rare developmental abnormality, particularly rare in adult. Only few cases were reported. We could not find any report of adult nasal glial heterotopias that developed cerebral hemorrhage as a complication of the surgery.

  5. Titanisierung von Implantatoberflächen

    Science.gov (United States)

    Zimmermann, Hanngörg; Heinlein, Markus; Guldner, Norbert W.

    Titan gilt seit Jahrzehnten als einer der wichtigsten Implantatwerkstoffe in der Medizin. Neben den guten mechanischen Eigenschaften (Leichtigkeit, hohe Festigkeit etc.), besitzen Titanimplantate vor allem eine hervorragende Körperverträglichkeit, so dass die Implantate optimal in den humanen Organismus integriert werden [1]. Ist jedoch aufgrund der Anforderungen an das Implantat eine hohe Flexibilität und/ oder Elastizität gefragt, so scheidet der Werkstoff Titan aufgrund seiner spröden und unflexiblen Materialeigenschaften aus. Die Folge ist der Einsatz von Implantatmaterialien, sowohl künstlichen als auch biologischen Ursprungs, welche nicht selten eine unzureichende Biokompatibilität aufweisen und somit zu Fremdköper- und immunologischen Reaktionen und Einkapselung des Implantates führen können. Die Erhöhung der Körperverträglichkeit, eine Adaption an das biologische Umfeld und eine hohe Biokompatibilität sind demzufolge die wichtigsten Eigenschaften bei der bedarfsgerechten Herstellung von Implantaten und Implantatoberflächen. Zur Gestaltung von innovativen, biokompatiblen Oberflächen stehen unterschiedliche technische Lösungsansätze zur Verfügung. Zum einen besteht die Möglichkeit, geeignete Oberflächeneigenschaften aus dem Grundmaterial selbst zu optimieren. Dies geschieht unter anderem durch Modifikation der Werkstoffoberflächen in Form von Texturierungen und Oberflächenrauhigkeiten. Zum anderen können die Oberflächeneigenschaften unabhängig von denen des Trägermaterials gestaltet werden. Durch Funktionalisierung der Oberflächen mit geeigneten Beschichtungen oder der Zugabe von Medikamenten (Drug Eluting) werden die Kunststoffimplantate dahingehend verändert, dass eine Steigerung der Körperakzeptanz erreicht wird. Die Titanbeschichtung von Implantatoberflächen kombiniert die positiven Materialeigenschaften von Titan und Polymer.

  6. 50th birthday of Christian von Ferber

    Directory of Open Access Journals (Sweden)

    2011-06-01

    Full Text Available On May 15, 2011 Christian von Ferber - member of the Editorial Board of "Condensed Matter Physics" and renowned expert in the fields of soft matter physics and complex systems - celebrated his 50th birthday. The Editorial board of CMP, colleagues and friends warmy congratulate Christian von Ferber and wish him and his family continuing good health and to enjoy many adventures and discoveries in his future scientific travels!

  7. The classification problem for von Neumann factors

    DEFF Research Database (Denmark)

    Sasyk, R.; Törnquist, Asger Dag

    2009-01-01

    We prove that it is not possible to classify separable von Neumann factors of types II, II or III, 0 ≤ λ ≤ 1, up to isomorphism by a Borel measurable assignment of "countable structures" as invariants. In particular the isomorphism relation of type II factors is not smooth. We also prove...... that the isomorphism relation for von Neumann II factors is analytic, but is not Borel....

  8. Hullud päevad von Krahlis

    Index Scriptorium Estoniae

    2006-01-01

    Von Krahli Teatris mängitakse neil päevi neli korda Peeter Jalaka lavastuses Tõnu Kõrvitsa kammeroopereid "Tuliaed" ja "Mu luiged, mu mõtted", mille aluseks on luuletaja Marie Heibergi saatus. Libreto autor on Maarja Kangro. Kammerooperid tulevad lavale Von Krahli Teatri ja Nargen Opera koostöös. Esitavad Kädy Plaas, Helen Lokuta, Nargen Opera koor ja Tallinna Kammerorkester, dirigent Tõnu Kaljuste

  9. Bedeutung von Umwelt- und Organismusfaktoren bei Autoaggressionen

    OpenAIRE

    Rohmann, Ulrich H.; Elbing, Ulrich; Hartmann, Hellmut

    1988-01-01

    In der vorliegenden Arbeit werden übergeordnete Hypothesen zu autoaggressiven Verhaltensweisen formuliert, wobei prozeßhafte Abläufe von umweltbezogenen und organischen Variablen angenommen werden. Eine solche dynamische Beziehung hat ihre Bedeutung sowohl für verursachende als auch aufrechterhaltende Faktoren. In einer Querschnittuntersuchung lassen sich Korrelationen von Tageszeit- und Tätigkeitscharakteristiken (umweltbezogene Variablen) zur Autoaggressionshäufigkeit und Pulsfrequenz (Orga...

  10. Status reports on the development and application of acoustic emission analysis. Proceedings; Statusberichte zur Entwicklung und Anwendung der Schallemissionsanalyse. Beitraege

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2017-08-01

    The colloquium lectures represent the wide range of applications in acoustic emission analysis and testing in the areas of damage development and damage mechanisms, testing of components, condition monitoring, development of new measuring systems and sensors as well as software development regarding locating methods and signal analysis. One focus of the colloquium is on current hardware and software developments for status monitoring by means of AE monitoring. One of the papers was separately analyzed for this database. [German] Die Vortraege des Kolloquiums repraesentieren das breite Spektrum der Anwendungen der Schallemissionsanalyse und -pruefung in den Bereichen der Schadensentwicklung und Schadensmechanismen, Pruefung von Bauteilen, Zustandsueberwachung, Entwicklung neuer Messsysteme und Sensoren sowie Softwareentwicklung bezueglich Ortungsverfahren und Signalanalyse. Ein Schwerpunkt des Kolloquiums betrifft aktuelle Hard- und Softwareentwicklungen zur Zustandsueberwachung durch AE-Monitoring.

  11. Using neuronal nets for modelling and control of internal combustion engines; Der Einsatz neuronaler Netze zur Modellierung, Steuerung und Regelung von Verbrennungsmotoren

    Energy Technology Data Exchange (ETDEWEB)

    Isermann, R.; Hafner, M.; Mueller, N.; Schueler, M. [Technische Univ. Darmstadt (Germany). Inst. fuer Regelungstechnik

    1999-07-01

    Design and testing of digital electronic control systems necessitate relatively accurate mathematical models of the static and dynamic characteristics of internal combustion engines. Control variables are injection volume, injection angle, ignition point and several others, which means a large number of characteristic fields and long measuring times in engine test stands. Neuronal nets enable a more compact description than characteristic field grids and are also more easily adaptable in test stand measurements. The contribution describes a particularly favourable local linear radial basis function net (LOLIMOT) and shows how it can be used for modelling the steady-state and dynamic exhaust characteristics of a diesel engine and the dynamic characteristics of an exhaust turbocharger. It also shows how combustion chamber control with adaptive control of the ignition pooint can be designed for a spark ignition engine with the aid of a neuronal net. [German] Entwurf und Test von digitalelektronischen Steuerungen und Regelungen erfordern in zunehmendem Masse relativ genaue mathematische Modelle fuer das statische und dynamische Gesamtverhalten von Verbrennungsmotoren. Ausser den Stellgroessen Einspritzmenge, Einspritzwinkel und Zuendzeitpunkt kommen noch weitere Stellgroessen hinzu. Die Zahl der in modernen Motorsteuerungen zu realisierenden Kennfelder steigt deshalb sehr stark an und damit auch die erforderliche Messzeit an Motorenpruefstaenden. Kuenstliche neuronale Netze bieten nun die Moeglichkeit, mehrdimensionale Kennfelder wesentlich kompakter zu beschreiben als Rasterkennfelder. Sie erlauben ausserdem eine wesentlich bessere Adaption bei Pruefstandsversuchen. Im Beitrag wird ein besonders geeignetes lokal lineares Radial-Basis-Funktions-Netz (LOLIMOT) beschrieben und dessen Anwendung gezeigt zur Modellierung des stationaeren und dynamischen Abgasverhaltens eines Dieselmotors und des dynamischen Verhaltens eines Abgas-Turboladers. Dann wird gezeigt, wie man eine

  12. Contested Inclusions: Pitfalls of NGO Peace-Building Activities in Liberia Umstrittene Inklusion: Fallstricke bei peace-building-Aktivitäten von NRO in Liberia

    Directory of Open Access Journals (Sweden)

    Veronika Fuest

    2010-01-01

    Full Text Available In post-war situations, non-governmental organizations (NGOs feature highly in peace-building processes in their (perceived capacities as both representatives of civil society and as grassroots agents to be employed in the reconstruction and transformation of society. As elsewhere, in Liberia, peace-building approaches include, first, international blueprints of representation that intend to empower groups generally perceived to be socially subordinate and, second, supporting traditional institutions considered social capital in reconciliation. Using the example of Liberia, this paper explores how in local conflict arenas, NGO workshops – the most popular mode of participatory intervention – are interpreted and appropriated by local actors; it highlights some fallacies and unintended consequences of inclusive procedures in practice and questions the support furnished to heads of gendered secret societies. Nichtregierungsorganisationen (NRO wird in Nachkriegsphasen hohe Kompetenz in Bezug auf peace-building-Prozesse zugesprochen, denn sie repräsentieren die civil society und stellen gleichzeitig Akteure, die an der Basis zum Wiederaufbau und zur gesellschaftlichen Transformation beitragen können. Auch in Liberia schließen peace-building-Konzepte an erster Stelle international erarbeitete Zielvorgaben zur Repräsentanz ein und sehen erstens eine Beteiligung von Gruppen mit niedrigem sozialen Status vor und zweitens die Unterstützung traditioneller Institutionen, die als soziales Kapital im Aussöhnungsprozess angesehen werden. Die Autorin untersucht am Beispiel Liberia, inwieweit NRO-workshops – die beliebteste Form der partizipativen Intervention – in Konfliktzonen von lokalen Akteuren interpretiert und für eigene Ziele genutzt werden; sie verweist auf irrtümliche Annahmen und unbeabsichtigte Konsequenzen der praktischen Anwendung inklusiver Verfahren und stellt die Unterstützung in Frage, die Oberhäuptern geschlechtsspezifischer

  13. Development and application of a new tool in driver task analysis; Entwicklung und Anwendung einer neuen Methodik zur Fahreraufgabenanalyse

    Energy Technology Data Exchange (ETDEWEB)

    Fastenmeier, W.; Gstalter, H. [mensch-verkehr-umwelt Institut fuer Angewandte Psychologie, Muenchen (Germany)

    2003-07-01

    A framework for driver task analysis is derived from a model of the drivers information processing. The first step of the procedure (SAFE) is to divide a given driving task (e.g. left turning in a signalised intersection of a certain type) into subtasks. These subtasks are appointed to defined stretches of the road and the time structure of the subtasks is determined. For each subtask an analysis format is used, that organizes different requirements into perception, expectation, judgement, memory, decision and driver action. In a next step, typical driver errors are appointed to the subtasks. Afterwards the information gathered in the analysis procedure is compressed to ratings of the complexity and risk included in each subtask. After the crucial subtasks of a driving task have been determined, a list of those requirements that led to that rating can be compiled. These lists give the potential for aiding the driver e.g. by use of driver assistance systems. (orig.) [German] In den Verkehrswissenschaften existieren bislang keine verkehrsspezifischen Standardverfahren, die eine Anforderungsanalyse auf der Ebene der Fahraufgaben erlauben. Dieser Beitrag stellt die Grundzuege eines Verfahrens zur Fahraufgabenanalyse dar (SAFE: Situative Anforderungsanalyse von Fahraufgaben). Es basiert auf einer Modellvorstellung zu den Informationsverarbeitungsprozessen, die waehrend der Bewaeltigung der Fahraufgabe eine Rolle spielen. Der erste Schritt der Aufgabenanalyse besteht darin, eine ausgewaehlte Fahraufgabe (z.B. Linksabbiegen in einer ampelgeregelten Kreuzung bestimmten Typs) in Teilaufgaben zu zerlegen und eine zeitliche Strukturierung dieser Teilaufgaben vorzunehmen. Diese werden raeumlichen Segmenten zugeordnet, die nacheinander durchfahren werden muessen. Fuer jede Teilaufgabe erfolgt dann die eigentliche Anforderungsanalyse, die nach den Kapiteln Wahrnehmung, Erwartungsbildung, Beurteilung, Gedaechtnisprozesse, Entscheidung/Planung sowie Fahrzeugbedienung mit jeweils

  14. Visualisierung von typisierten Links in Linked Data

    Directory of Open Access Journals (Sweden)

    Georg Neubauer

    2017-09-01

    Full Text Available Das Themengebiet der Arbeit behandelt Visualisierungen von typisierten Links in Linked Data. Die wissenschaftlichen Gebiete, die im Allgemeinen den Inhalt des Beitrags abgrenzen, sind das Semantic Web, das Web of Data und Informationsvisualisierung. Das Semantic Web, das von Tim Berners Lee 2001 erfunden wurde, stellt eine Erweiterung zum World Wide Web (Web 2.0 dar. Aktuelle Forschungen beziehen sich auf die Verknüpfbarkeit von Informationen im World Wide Web. Um es zu ermöglichen, solche Verbindungen wahrnehmen und verarbeiten zu können sind Visualisierungen die wichtigsten Anforderungen als Hauptteil der Datenverarbeitung. Im Zusammenhang mit dem Sematic Web werden Repräsentationen von zuhammenhängenden Informationen anhand von Graphen gehandhabt. Der Grund des Entstehens dieser Arbeit ist in erster Linie die Beschreibung der Gestaltung von Linked Data-Visualisierungskonzepten, deren Prinzipien im Rahmen einer theoretischen Annäherung eingeführt werden. Anhand des Kontexts führt eine schrittweise Erweiterung der Informationen mit dem Ziel, praktische Richtlinien anzubieten, zur Vernetzung dieser ausgearbeiteten Gestaltungsrichtlinien. Indem die Entwürfe zweier alternativer Visualisierungen einer standardisierten Webapplikation beschrieben werden, die Linked Data als Netzwerk visualisiert, konnte ein Test durchgeführt werden, der deren Kompatibilität zum Inhalt hatte. Der praktische Teil behandelt daher die Designphase, die Resultate, und zukünftige Anforderungen des Projektes, die durch die Testung ausgearbeitet wurden.

  15. Seasonal changes in nasal cytology in mite-allergic patients

    Directory of Open Access Journals (Sweden)

    Gelardi M

    2014-03-01

    Full Text Available Matteo Gelardi,1 Diego G Peroni,2 Cristoforo Incorvaia,3 Nicola Quaranta,1 Concetta De Luca,1 Salvatore Barberi,4 Ilaria Dell'Albani,5 Massimo Landi,6 Franco Frati,5 Olivier de Beaumont7 1Otolaryngology Unit, Department of Neuroscience and Sensory Organs, University of Bari, Bari, Italy; 2Department of Pediatrics, University of Verona, Verona, Italy; 3Allergy/Pulmonary Rehabilitation, ICP Hospital, Milan, Italy; 4Department of Pediatrics, San Paolo Hospital, Milan, Italy; 5Medical and Scientific Department, Stallergenes, Milan, Italy; 6Department of Pediatrics, National Healthcare System, ASL TO1, Turin, Italy; 7Medical Affairs Department, Stallergenes, Antony, France Background: House dust mites (HDMs are a major cause of allergic rhinitis (AR and asthma worldwide. Recent studies suggested that the allergen load presents seasonal modifications, giving rise to seasonal variation in nasal inflammation and symptoms. The aim of this study was to evaluate by nasal cytology whether nasal inflammation in mite-allergic patients changes with the seasons of the year. Methods: The study included 16 patients (seven males and nine females, mean age 38.1 years with persistent AR caused by monosensitization to HDMs. Nasal cytology was performed in all patients once monthly for 1 year. Results: Nasal cytology showed that the cells most commonly detected in the nasal mucosa were neutrophils. During the period from October to April, a peak in the number of neutrophils and also the presence of significant numbers of eosinophils, mast cells, and lymphocytes/plasma cells were found, which shows the occurrence of more intense inflammation during these months. Conclusion: Nasal cytology provides useful data in detecting nasal inflammation and its association with the clinical stage of AR. The seasonal variations in nasal cytology are likely to be induced by the fluctuations in the HDM allergen that have been uncovered in recent investigations. Keywords: allergens

  16. Nasal allergies hayfever among young adults in Melbourne, Australia

    Directory of Open Access Journals (Sweden)

    Michael Abramson

    1997-01-01

    Full Text Available Although there is wide variation in the prevalence of nasal allergies internationally, the extent to which this is due to variation in etiological factors is not known. The purpose of the present study was to define the relative importance of atopy and other risk factors for nasal allergies, including hayfever, among young adults in Melbourne. The subjects were participants in the second phase of the European Community Respiratory Health Survey; 876 adults between 20 and 45 years of age completed a detailed respiratory questionnaire, 745 had skin prick testing with common aeroallergens and 675 underwent methacholine challenge. Total and allergen-specific IgE levels were measured in 701 and 693 subjects by radioimmunoassay and RAST, respectively. Nasal allergies, including hayfever, were reported by 47.5% of randomly selected participants. Females, non- smokers, subjects with a family history of allergies, those with current asthma, a history of eczema and nasal symptoms induced by dust, pollen or food were significantly more likely to have nasal allergies. Oral antihistamines had been used by 45.7% of those reporting nasal allergies and 12.4% had received allergen immunotherapy. The risk of nasal allergies, including hayfever, was increased 6.1-fold by atopy, particularly by positive skin tests to outdoor allergens such as Birch, Timothy grass, plantain, olive, Cladosporium and Rye grass pollen. Total serum IgE was significantly higher in subjects reporting nasal allergies than in those who did not report such allergies. There were significant trends in the prevalence of nasal allergies with increasing titers of specific IgE directed against all allergens tested. In conclusion, the significant independent risk factors for nasal allergies, including hayfever, in young adults were atopy, particularly sensitization to Timothy grass, house dust mites and plantain, current asthma, not smoking, a history of eczema and female gender. Future research

  17. Objective measurements for grading the nasal esthetics on Basal view in individuals with secondary cleft nasal deformity.

    Science.gov (United States)

    He, Xing; Li, Hua; Shao, Yan; Shi, Bing

    2015-01-01

    The purpose of this study is to ascertain objective nasal measurements from the basal view that are predictive of nasal esthetics in individuals with secondary cleft nasal deformity. Thirty-three patients who had undergone unilateral cleft lip repair were retrospectively reviewed in this study. The degree of nasal deformity was subjectively ranked by seven surgeons using standardized basal-view measurements. Nine physical objective parameters including angles and ratios were measured. Correlations and regressions between these objective and subjective measurements were then analyzed. There was high concordance in subjective measurements by different surgeons (Kendall's harmonious coefficient = W = .825, P = .006). The strongest predictive factors for nasal aesthetics were the ratio of length of nasal alar (r = .370, P = .034) and the degree of deviation of the columnar axis (r = .451, P = .008). The columellar angle had a more powerful effect in rating nasal esthetics. There was reliable concordance in subjective ranking of nasal esthetics by surgeons. Measurement of the columnar angle may serve as an independent, objective predictor of esthetics of the nose.

  18. Effects of nasal drug delivery device and its orientation on sprayed particle deposition in a realistic human nasal cavity.

    Science.gov (United States)

    Tong, Xuwen; Dong, Jingliang; Shang, Yidan; Inthavong, Kiao; Tu, Jiyuan

    2016-10-01

    In this study, the effects of nasal drug delivery device and the spray nozzle orientation on sprayed droplets deposition in a realistic human nasal cavity were numerically studied. Prior to performing the numerical investigation, an in-house designed automated actuation system representing mean adults actuation force was developed to produce realistic spray plume. Then, the spray plume development was filmed by high speed photography system, and spray characteristics such as spray cone angle, break-up length, and average droplet velocity were obtained through off-line image analysis. Continuing studies utilizing those experimental data as boundary conditions were applied in the following numerical spray simulations using a commercially available nasal spray device, which was inserted into a realistic adult nasal passage with external facial features. Through varying the particle releasing direction, the deposition fractions of selected particle sizes on the main nasal passage for targeted drug delivery were compared. The results demonstrated that the middle spray direction showed superior spray efficiency compared with upper or lower directions, and the 10µm agents were the most suitable particle size as the majority of sprayed agents can be delivered to the targeted area, the main passage. This study elaborates a comprehensive approach to better understand nasal spray mechanism and evaluate its performance for existing nasal delivery practices. Results of this study can assist the pharmaceutical industry to improve the current design of nasal drug delivery device and ultimately benefit more patients through optimized medications delivery. Copyright © 2016 Elsevier Ltd. All rights reserved.

  19. [Study on computed tomography features of nasal septum cellule and its clinical significance].

    Science.gov (United States)

    Huang, Dingqiang; Li, Wanrong; Gao, Liming; Xu, Guanqiang; Ou, Xiaoyi; Tang, Guangcai

    2008-03-01

    To investigate the features of nasal septum cellule in computed tomographic (CT) images and its clinical significance. CT scans data of nasal septum in 173 patients were randomly obtained from January 2001 to June 2005. Prevalence and clinical features were summarized in the data of 19 patients with nasal septum cellule retrospectively. (1) Nineteen cases with nasal septum cellule were found in 173 patients. (2) All nasal septum cellule of 19 cases located in perpendicular plate of the ethmoid bone, in which 8 cases located in upper part of nasal septum and 11 located in middle. (3) There were totally seven patients with nasal diseases related to nasal septum cellule, in which 3 cases with inflammation, 2 cases with bone fracture, 1 case with cholesterol granuloma, 1 case with mucocele. Nasal septum cellule is an anatomic variation of nasal septum bone, and its features can provide further understanding of some diseases related to nasal septum cellule.

  20. Time and environmental science. Pt. 2. Time and fundamental concepts; Die Bedeutung der Zeit. T. 2. Die Umweltwissenschaften im Kontext von Zeit: Begriffe unter dem Aspekt der Zeit

    Energy Technology Data Exchange (ETDEWEB)

    Kuemmerer, K. [Inst. fuer Umweltmedizin und Krankenhaushygiene, Freiburg (Germany); Held, M. [Evangelische Akademie, Tutzing (Germany)

    1997-06-01

    Forschungsergebnisse von grundlegender Bedeutung sind wie z.B. Persistenz von Schadstoffen, Irreversibilitaet von Veraenderungen, Schaden und Schaedigung und auch Elastizitaet oder Resilience von Oekosystemen. Insbesondere Zeitskalen und Rhythmen sowie deren Vielfalt sind dafuer von Bedeutung. Hinsichtlich ihrer Persistenz besonders kritische Stoffe zeichnen sich dadurch aus, dass ihre Reaktivitaet zwar so gering ist, dass sie fuer die Anwendung stabil genug sind, die Reaktivitaet aber noch in gewissem Mass vorhanden ist und sie eine nicht zu hohe Transportrate besitzen. Persistenz ist somit ein vom Kontext abhaengiges Kriterium. Ob Aenderungen als reversibel oder irreversibel einzustufen sind, ist von den betrachteten Zeitraeumen und jeweiligen Systemen, deren Beschreibung und den hierfuer ausgewaehlten Parametern abhaengig. Voraussetzungen fuer den Fortbestand eines Systems zu schaffen, bedeutet u.a. die systemeigene Entwicklungsgeschwindigkeit und die Verschraenktheit unterschiedlicher Zeitskalen zu beachten. Wenn Stoerungen, die zu schnellen Aenderungen und somit zu kritischen Fluktuationen fuehren, vermieden werden, koennen sich oekologische Systeme entsprechend ihrer eigenen Dynamik weiterentwickeln. Die Dauer von Stoerungen sollte moeglichst kurz sein, um anthropogene, im Vergleich zur systemeigenen Zeitskala schnelle Veraenderungen von Oekosystemen zu minimieren. (orig.)

  1. Analyses and treatments of postoperative nasal complications after endonasal transsphenoidal resection of pituitary neoplasms

    Science.gov (United States)

    Cheng, You; Xue, Fei; Wang, Tian-You; Ji, Jun-Feng; Chen, Wei; Wang, Zhi-Yi; Xu, Li; Hang, Chun-Hua; Liu, Xin-Feng

    2017-01-01

    Abstract In this study, we analyze and discuss the treatments of postoperative nasal complications after endonasal transsphenoidal resection of pituitary neoplasms (PNs). We performed 129 endonasal transsphenoidal resections of PNs and analyzed and treated cases with nasal complications. After endonasal transsphenoidal resection of PNs, there were 26 cases of postoperative nasal complications (20.1%), including nasal hemorrhage (4.8%), cerebrospinal fluid rhinorrhea (6.9%), sphenoid sinusitis (2.3%), atrophic rhinitis (1.6%), olfactory disorder (1.6%), perforation of nasal septum (0.8%), and nasal adhesion (2.3%). All patients clinically recovered after therapy, which included treatment of the cavity through nasal endoscopy, intranasal corticosteroids, and nasal irrigation. We propose that regular nasal endoscopic review, specific nasal medications, and regular nasal irrigation can effectively clear nasal mucosal hyperemia-induced edema and nasal/nasoantral secretions, as well as promote regeneration of nasal mucosa, prevent nasal adhesion, maintain the sinus cavity drainage, and accelerate the recovery of the physiological function of the paranasal sinus. Timely treatment of patients with nasal complications after endonasal transsphenoidal resections of PNs could greatly relieve the clinical symptoms. Nasal cleaning is very beneficial to patients after surgery recovery. PMID:28403108

  2. A Comparison of Over-the-Counter Mechanical Nasal Dilators: A Systematic Review.

    Science.gov (United States)

    Kiyohara, Nicole; Badger, Christopher; Tjoa, Tjoson; Wong, Brian

    2016-09-01

    The internal nasal valve is the narrowest part of the nasal airway and a common site of inspiratory collapse and obstruction of nasal airflow. Over-the-counter mechanical nasal dilators are an alternative to surgical intervention that attempts to improve airflow through the internal nasal valve. To determine the efficacy of over-the-counter mechanical nasal dilators and classify these products by mechanism. A database of 33 available over-the-counter mechanical nasal dilators was generated via a PubMed search as well as an internet search via Amazon.com and Google, conducted from April 1, 2013, through December 31, 2015. Products determined to be unavailable or discontinued were excluded from the database. Of the devices examined in published literature, efficacy was based on objective measures, such as measured airflow, the cross-sectional area of the nasal valve, and changes in resistance. Measures of reported sleep quality or patient perception were excluded. An analysis of each product's mechanism revealed 4 broad classes: external nasal dilator strips, nasal stents, nasal clips, and septal stimulators. A review demonstrated 5 studies supporting the use of external nasal dilator strips, 4 studies supporting the use of nasal clips, 1 study supporting the use of nasal stents, and no studies supporting the use of septal stimulators. Our findings suggest that external nasal dilator strips and nasal clips effectively relieve obstruction of the internal nasal valve and may be an alternative to surgical intervention in some patients.

  3. Anatomy of the fingers in MR imaging using a high resolution surface coil; Die Anatomie der Finger in der MRT unter Anwendung einer Hochaufloesungsspule

    Energy Technology Data Exchange (ETDEWEB)

    Maeurer, J. [Strahlenklinik und Poliklinik, Klinikum Rudolf Virchow, Standort Wedding, Freie Univ. Berlin (Germany); Mueller, H.F. [Strahlenklinik und Poliklinik, Klinikum Rudolf Virchow, Standort Wedding, Freie Univ. Berlin (Germany); Lemke, A.J. [Strahlenklinik und Poliklinik, Klinikum Rudolf Virchow, Standort Wedding, Freie Univ. Berlin (Germany); Requardt, R. [Siemens AG, Erlangen (Germany); Stein, I. [Strahlenklinik und Poliklinik, Klinikum Rudolf Virchow, Standort Wedding, Freie Univ. Berlin (Germany); Schedel, H. [Strahlenklinik und Poliklinik, Klinikum Rudolf Virchow, Standort Wedding, Freie Univ. Berlin (Germany); Langer, R. [Strahlenklinik und Poliklinik, Klinikum Rudolf Virchow, Standort Wedding, Freie Univ. Berlin (Germany); Felix, R. [Strahlenklinik und Poliklinik, Klinikum Rudolf Virchow, Standort Wedding, Freie Univ. Berlin (Germany)

    1994-12-31

    MR-images of the fingers of twenty healthy volunteers were obtained at a 1,5-T whole-body system with a high resolution coil. Additionally, the fingers of two formalin-fixed anatomical specismen were imaged, fronzen and then subsequently sectioned for anatomic correlation. Measurements were recorded with a slice thickness of 2 mm. A 256x256 matrix and a 2,5 cam fiel of view (FOV) were used resulting in a pixel size of 0,01 mm{sup 2}. Based on the excellent depiction of anatomic detail and contrast resolution high resolution MRI of the fingers enabled identification of osseous and cartilaginous structures, as well as delineation of tendons, ligaments blood-vessels and dermal layers. (orig.) [Deutsch] An einem 1,5-T-Ganzkoerpertomographen wurden die Finger von 20 gesunden Probanden mit einer Hochaufloesungsspule zur Darstellung der Anatomie untersucht. Zum Vergleich erfolgte die Abbildung der anatomischen Strukturen an zwei formol- und alkoholfixierten Leichepraeparaten der Hand mittels MRT. Im Anschluss wurden die untersuchten Regionen am tiefgefrorenen Praeparat mit einer Bandsaege nachgeschnitten. Die MR-Messungen wurden mit einer Schichtdicke von 3 mm, einem Field of View (FOV) von 25 mm und einer Matrix von 256x256 Pixel durchgefuehrt. Die daraus resultierende Pixelgroesse betrug 0,01 mm{sup 2}. Der Weichteilkontrast und die hohe Ortsaufloesung ermoeglichten die Identifikation von Knochen- und Knorpelstrukturen sowie die Abgrenzung von Sehnen, Baendern, Blutgefaessen und Hautschichten. (orig.)

  4. SOME ASPECTS OF NASAL CARRIAGE OF STAPHYLOCOCCI.

    Science.gov (United States)

    NOBLE, W C; WILLIAMS, R E; JEVONS, M P; SHOOTER, R A

    1964-01-01

    The nasal carrier status of 3,736 patients was determined throughout their stay in hospital. The carrier rate on admission, which was highest in patients under 20 years of age, did not appear to vary with season.The carriage of strains resistant to penicillin increased with the patients' stay in hospital from 13.% on admission to 20.5% on discharge, and the acquisition of these strains was enhanced by the administration of antibiotics. Patients discharged from hospital carrying strains of staphylococci acquired in hospital lost them more readily than patients discharged carrying the strain which they had carried on admission, 31% of those discharged carrying strains resistant to penicillin and tetracycline being readmitted carrying these strains compared with 69% of those discharged carrying strains sensitive to these antibiotics.

  5. Characterizing adult human nasal airway dimensions

    International Nuclear Information System (INIS)

    Guilmette, R.A.; Griffith, W.C.

    1994-01-01

    Respiratory tract models used in calculating radiation dose from exposure to inhaled radioactive aerosols have only recently focused attention on the importance of the nasal airways (NAs). Because the NAs are the first tissues of the respiratory tract available for aerosol deposition in normally nose-breathing people, any deposition of aerosol in this anatomical structure will reduce the amounts available to be deposited in the remainder of the respiratory tract. Thus, uncertainties in estimating the deposition fractions in the NAs will propagate throughout the remainder of the respiratory tract, creating errors in the calculated dose estimates. Additionally, there is evidence that the NAs are also at risk for induction of cancer from exposure to certain occupational aerosols such as wood dust, leather dust, chromium, and nickel. The purpose of this investigation was to conduct an anatomical study to assess the variabilities in NA dimensions

  6. Efficacy of functional endoscopic sinus surgery in recurrent nasal polyposis

    International Nuclear Information System (INIS)

    Aslam, S.; Ali, M.; Ahmed, A.; Asghar, A.; Aslam, S.

    2014-01-01

    To analyze the efficacy of FESS in patients with recurrent nasal polyposis in terms of relief of nasal obstruction, improvement in sense of smell and to assess recurrence of disease. Study Design: Descriptive case series. Materials and Method: All patients who underwent FESS (Functional endoscopic sinus surgery) for recurrent nasal polyposis from June 2008 to June 2010 with an average follow up of 06 month were included. Clinical symptoms including nasal obstruction and olfactory disturbance were evaluated using VAS system pre and postoperatively. Preoperatively computed tomography scan was done in all cases to assess extent of disease and surgical anatomy. Results: Following FESS 96% of total patients demonstrated statistically significant improvement in relieving nasal obstruction after 6 months follow up, however improvement in sense of smell was seen in 44% of patients. Recurrence was seen in only 3 (6%) cases at 3rd and 6th month follow up. Conclusion: Functional endoscopy sinus surgery of recurrent nasal polyposis is an effective method of surgery with significant improvement of symptom of nasal obstruction and olfaction with minimal recurrence at 6 month in our centre. Our results were compatible with results attained internationally. (author)

  7. Congenital Midline Nasal Mass: Four Cases with Review of Literature

    Directory of Open Access Journals (Sweden)

    Sambhaji Govind Chintale

    2017-12-01

    Full Text Available Introduction Congenital midline nasal masses include nasal dermoids, gliomas, encephaloceles. Although rare, these disorders are clinically important because of their potential for connection to the central nervous system. Preoperative knowledge of an intracranial connection is a necessity to allow for neurosurgical consultation and possible planning for craniotomy. This study discusses the clinical presentation of congenital midline nasal mass and the role of imaging modalities like CT scan and MRI in diagnosis and the surgical management. Materials and Methods  This prospective study is carried from March 2014 to March 2016, during which 4 cases presented to the Otorhinolaryngology department. Pre-operative evaluation of the patients included endoscopic evaluation along with haematological investigations, CT Scan and MRI. The masses were removed with nasal endoscopic sinus surgery or by external approaches and neurosurgical intervention. Result The age of the patients ranged from 3 years to 25 years. Three of them were male and one female. There was one case of nasoethmoidal encephalocele and the other three were dermoids (intranasal dermoid cyst, nasal dermoid cyst and nasal dermoid sinus cyst. Conclusion Congenital midline nasal masses are rare. These disorders are clinically important because of their intracranial connection which require proper evaluation with radiological imaging like CT scan and/or MRI before FNAC and any surgical intervention.

  8. Inverted papillomas and benign nonneoplastic lesions of the nasal cavity

    Science.gov (United States)

    Casiano, Roy R.

    2012-01-01

    Background: Benign lesions of the nasal cavity represent a diverse group of pathologies. Furthermore, each of these disorders may present differently in any given patient as pain and discomfort, epistaxis, headaches, vision changes, or nasal obstruction. Although these nasal masses are benign, many of them have a significant capacity for local tissue destruction and symptomatology secondary to this destruction. Advances in office-based endoscopic nasendoscopy have equipped the otolaryngologist with a safe, inexpensive, and rapid means of directly visualizing lesions within the nasal cavity and the initiation of appropriate treatment. Methods: The purpose of this study is to review the diagnosis, management, and controversies of many of the most common benign lesions of the nasal cavity encountered by the primary care physician or otolaryngologist. Results: This includes discussion of inverted papilloma (IP), juvenile angiofibroma, squamous papilloma, pyogenic granuloma, hereditary hemorrhagic telangiectasia, schwannoma, benign fibro-osseous lesions, and other benign lesions of the nasal cavity, with particular emphasis on IP and juvenile angiofibroma. Conclusion: A diverse array of benign lesions occur within the nasal cavity and paranasal cavities. Despite their inability to metastasize, many of these lesions have significant capability for local tissue destruction and recurrence. PMID:22487294

  9. Evaluation of the nasal shape after orthognathic surgery.

    Science.gov (United States)

    Dantas, Wagner Ranier Maciel; Silveira, Márcia Maria Fonseca da; Vasconcelos, Belmiro Cavalcanti do Egito; Porto, Gabriela Granja

    2015-01-01

    Patients with dentofacial deformities may benefit from orthognathic surgery in the maxilla. Maxillary osteotomy may include procedures in the bone, cartilaginous, and soft tissues of the nose, leading to shape alterations. To evaluate the anatomic alterations of the nasal region in patients undergoing a Le Fort I osteotomy for advancement or superior impaction. This is a clinical prospective study. Twenty-one patients were evaluated during the pre- and postoperative periods. The positioning of the nasal tip and the modification of the nasal base were evaluated. The results showed that the nasal tip was superiorly positioned in 85% of the cases, advanced in 80%, rotated in 80%, and there was a wide nasal base in 95%, resulting in esthetic improvement. Surgeries of maxillary advancement and superior reposition tend to cause elevation and advancement of the nasal tip, as well as enlargement of the nasal base. Copyright © 2014 Associação Brasileira de Otorrinolaringologia e Cirurgia Cérvico-Facial. Published by Elsevier Editora Ltda. All rights reserved.

  10. Nasal bacterial colonization in cases of idiopathic epistaxis in children.

    Science.gov (United States)

    Kamble, Payal; Saxena, Sonal; Kumar, Sunil

    2015-11-01

    To evaluate the role of nasal bacterial colonization in cases of idiopathic epistaxis in children. A descriptive, hospital based, observational study in our hospital was conducted on total 112 pediatric patients in the age group 4-16 years. Group A (control): 56 patients with no epistaxis; Group B (epistaxis): 56 patients with idiopathic epistaxis. A swab for microbiological evaluation was taken from the anterior nasal cavity of each child. A highly significant association between nasal colonization with pathological Staphylococcus aureus and idiopathic epistaxis was found. The presence of pathological S. aureus colonization in the anterior nasal cavity was also associated with statistically significant number of crusting and presence of dilated blood vessels on the anterior nasal septum of children in epistaxis group. Nasal bacterial colonization with S. aureus leads to a sequence of pathological events i.e. low grade inflammation, crusting and new vessel formation. This leads to irritation in nasal cavity resulting in digital trauma and subsequently epistaxis and thus it plays an important role in causing idiopathic epistaxis in children. Copyright © 2015 Elsevier Ireland Ltd. All rights reserved.

  11. Treatment countermeasures for common problems in dacryocystorhinostomy under nasal endoscope

    Directory of Open Access Journals (Sweden)

    Zhong-Ling Luo

    2014-04-01

    Full Text Available AIM: To discuss the common problems and treatment countermeasures in dacryocystorhinostomy under nasal endoscope.METHODS: The clinical data of 37 cases(43 eyesof postoperative dacryocystorhinostomy under nasal endoscope, by using high-frequency electric knife to open the nasal mucosa, hemostasis in surgery, burning fixed lacrimal sac mucosal flap and nasal mucosal flap, methylene blue staining of the lacrimal sac, lacrimal drainage tube implanted and expansion foam support fixed anastomotic methods were reviewed in our hospital from Mar. 2011 to June. 2013. The effects of surgery were observed, and the intraoperative common questions and the treatments were discussed.RESULTS: In the 37 cases(43 eyes, 42 eyes(97.7%were cured, and 1 eye was improved, and the total efficiency was 100%. All operations were successfully completed without any serious complications during surgery.CONCLUSION: The common complication in dacryocystorhinostomy under nasal endoscope are effectively treated and the success rates of surgery are improved, by using high-frequency electric knife to open the nasal mucosa, hemostasis in surgery, burning fixed lacrimal sac mucosal flap and nasal mucosal flap, methylene blue staining of the lacrimal sac, lacrimal drainage tube implanted and expansion foam support fixed anastomotic methods. These methods are worthy of application and promotion.

  12. Nasal non-hodgkin's lymphoma : CT findings

    Energy Technology Data Exchange (ETDEWEB)

    No, Tae Youn; Baek, Ho Gil; Won, Jong Bu; Park, Sung Ho; Park, O Bong; Baik, Seung Kug; Shin, Mi Jung; Kim, Bong Ki; Choi, Han Yong [Wallace Memorial Baptist Hospital, Pusan (Korea, Republic of)

    1997-05-01

    To describe the characteristics of CT findings in nasal lymphoma. We retrospectively reviewed CT findings and pathologic findings of eight patients (six males and two females) aged between 24 and 68 years with pathologically-proven nasal lymphoma. We analyzed mass location, laterality, size, margin, mass effect, adjacent bony change and contrast enhancement pattern. All eight cases were non-Hodgkin's lymphoma, intermediate grade, diffuse large cell type. Seven cases were B-cell type and one was T-cell. In all cases, tumors were located in the medial wall of the inferior turbinate. In four cases, they were also found in the anterior ethmoidal sinus, and in one case, in the nasal septum. The mean size of the main mass was 3.3cm. In seven cases, tumors were unilateral (one on the right; six on the left), and in the remaining case, bilateral. In six cases tumor margin was smooth and in two cases focal nodularity was seen. In two cases there was no bony change, and in four, there was mucosal thickening along the nasal septum; in one of these four, minimal bony erosion was also found. In the other two cases, bony destruction was seen, and tumors were very large(7cm in diameter) or bilterally located. In three cases, the nasal septum was displaced by the mass. In all cases with bony change, the nasal septum was involved. All tumors were homogeneously well enhanced after IV contrast administration. The main CT findings of nasal non-Hodgkin's lymphoma were smooth margin, unilateral location (mainly in the medial wall of the inferior turbinate and growing to the medial side without bony destruction) mucosal thickening along the nasal septum and clear homogeneous enhancement after IV contrast administration. These characteristics will help diagnosis, help deter-mine the appropriate region for radiation and other appropriate therapy, and facilitate prognosis in patients with nasal non-Hodgkin's lymphoma.

  13. Nasal valve evaluation in the Mexican-Hispanic (mestizo) nose.

    Science.gov (United States)

    Jasso-Ramírez, Elizabeth; Sánchez Y Béjar, Fernando; Arcaute Aizpuru, Fernando; Maulen Radován, Irene E; de la Garza Hesles, Héctor

    2018-04-01

    Our aim in this study was to determine the angle of the internal nasal valve in Mexican patients with the "mestizo nose" feature and without nasal obstructive symptoms. The work was prospective, comparative, and observational in nature and included patients >14 years of age who were seen in the Otolaryngology Department at the Los Angeles Lomas Hospital between April and May 2016. The angle of the internal nasal valve was measured in 30 patients without obstructive symptoms. Endoscopic examination was performed with a 0° endoscope framed with tape at a 13-mm distance from the endoscope's tip, and digital photographs of the internal nasal valve were taken. The measurement of the angle of the internal nasal valve was made in sexagesimal degrees using Golden Ratio v3.1 (2012) software. Statistical analysis was performed using Excel v15.13.3. The angles of the internal nasal valve of the patients were (mean ± standard deviation) 24.07 ± 4.8° for the right nasal cavity and 25.07 ± 5.0° for the left nasal cavity, wider than the angle reported in the normal Caucasian nose established in the literature. According to our results, the Mexican-Hispanic mestizo nose has a wider angle in the internal nasal valve than that considered normal in the literature (10°-15°). We believe it is necessary to undertake a second study and add an airflow resistance measurement with a rhinomanometry procedure so we can compare the results with those in the Caucasian population. © 2018 ARS-AAOA, LLC.

  14. Angiofibroma of the nasal cavity in 13 dogs.

    Science.gov (United States)

    Burgess, K E; Green, E M; Wood, R D; Dubielzig, R R

    2011-12-01

    This case series describes a rare entity, nasal angiofibroma, in 13 dogs that were presented to the University of Wisconsin, School of Veterinary Medicine from 1988 to 2000. All dogs in this case series presented with clinical signs and radiographic changes that were strongly suggestive of a locally invasive neoplasm. However, histopathology completed on transnostral core biopsy samples revealed benign appearing vascular proliferation with secondary lymphosuppurative inflammation was established despite cytologic criteria of malignancy present in five dogs. On the basis of the outcomes in this case series, nasal angiofibroma should be considered a differential for dogs presenting with clinical signs consistent with a malignant nasal tumour. © 2011 Blackwell Publishing Ltd.

  15. Extranasopharyngeal angiofibroma of the nasal septum: a case report.

    Science.gov (United States)

    Mohindra, Satyawati; Grover, Gogia; Bal, Amanjit Kaur

    2009-11-01

    Angiofibroma arising outside the nasopharynx is unusual. The nasal septum is an extremely rare site for the origin of angiofibroma, and to date only 6 such cases previously have been reported in the literature. We report here a case of a 22-year-old man with a vascular mass arising from his nasal septum. The histopathology report was consistent with angiofibroma. We also review other cases in the literature of angiofibroma arising from the nasal septum and discuss a theory of the likely origin of angiofibroma.

  16. Solitary Chemoreceptor Cell Proliferation in Adult Nasal Epithelium

    OpenAIRE

    Gulbransen, Brian D.; Finger, Thomas E.

    2005-01-01

    Nasal trigeminal chemosensitivity in mice and rats is mediated in part by solitary chemoreceptor cells (SCCs) in the nasal epithelium (Finger et al., 2003). Many nasal SCCs express the G-protein α-gustducin as well as other elements of the bitter-taste signaling cascade including phospholipase Cβ2, TRPM5 and T2R bitter-taste receptors. While some populations of sensory cells are replaced throughout life (taste and olfaction), others are not (hair cells and carotid body chemoreceptors). These ...

  17. Strategy for Nasal Reconstruction in Atypical Facial Clefts

    Directory of Open Access Journals (Sweden)

    Fouad M. Ghareeb, FRCS, MD

    2017-11-01

    Full Text Available Summary:. It is difficult to put forward a strategy for the treatment of nasal clefts due to the rarity and diversity of anatomical aberrations of these cases contrary to the common nasal affection in cleft lip and palate patients, which differ in severity rather than differing in the morbid anatomy. This simple strategy for correction of these nasal clefts will hopefully help surgeons to achieve better results. In the mean time I intended to describe the morbid anatomy of these cases by choosing examples of each morbid anatomy.

  18. Nasal hyper-reactivity is a common feature in both allergic and nonallergic rhinitis

    NARCIS (Netherlands)

    Segboer, C. L.; Holland, C. T.; Reinartz, S. M.; Terreehorst, I.; Gevorgyan, A.; Hellings, P. W.; van Drunen, C. M.; Fokkens, W. J.

    2013-01-01

    Nasal hyper-reactivity is an increased sensitivity of the nasal mucosa to various nonspecific stimuli. Both allergic rhinitis (AR) and nonallergic rhinitis (NAR) patients can elicit nasal hyper-reactivity symptoms. Differences in the prevalence or type of nasal hyper-reactivity in AR and NAR

  19. ˝FLUMINENSIA˝ VON FRAN KURELAC

    Directory of Open Access Journals (Sweden)

    Leopoldina Veronika Banaš

    1990-01-01

    Full Text Available Das Buch "Fluminensia" (1862 von Fran Kurelac enthält die für die Schulfestlichkeiten geschriebenen Reden, Gelegenheitsgedichte - Ehrengedichte den bedeutenden und verdienstvollen Zeitgenossen gewidmet: dem Bischof von Senj und Modrus" Mirko Ožegović, Bartol Zmajic von Bakar, dem kroatischen Ban Josip Jelačić u.a. Danach folgen Aufrufe ("Proglasi" aus stürmischem 1848, gerichtet auf die Granzlandbewohner, Deutscher, ungarische Kroaten, Rumänen und Slawonier. Die Aufrufe wurden von Kurelac im Namen der Banalregierung beschrieben. Am Ende des Buches steht eine sprachwissenschaftliche Abhandlung über die ubstantivbiegung. Die für die Schulfestlichkeiten geschreibenen Reden sind wissenschaftliche Inhalte, essaystisch-didaktisch gestalltet, mit der Meldung über die Bedeutung der Wisenschaft, über die Bedeutung und Rolle der Sprache und des Buches für den Fortschritt des Volkes. Der Verfasser widmete dieses Buch seinen ehemaligen Schülern. "Fluminensia" nimmt eine wichtige Stelle in literarischer und sprachwissenschaftlicher Schöpfung auf dem Gebiet von Rijeka und Kroatien im 19. Jahrhundert ein.

  20. Privatiserung von Geschichte. Probleme einer differenzierten Aufarbeitung

    Directory of Open Access Journals (Sweden)

    Birthe Kundrus

    2000-11-01

    Full Text Available Ausgangspunkt der Untersuchung von Vera Neumann ist die These, daß im Krieg Erlebtes und Erlittenes in den Wiederaufbau- und Wirtschaftswunderjahren Westdeutschlands einem Thematisierungstabu unterlegen sei. Anhand von 50 Interviews, die in den 80er Jahren im Rahmen des von Lutz Niethammer geleiteten Projekts „Lebensgeschichte und Sozialgeschichte im Ruhrgebiet 1930–1960“ (LUSIR entstanden sind und die sie jetzt anhand der Tonbandprotokolle und Abschriften ein zweites Mal auswertet, möchte die Historikerin diese Verschüttungen aufspüren. Im Anschluß an Niethammers These der „Privatisierung von Geschichte“ will sie zeigen, daß seelische und körperliche Kriegsfolgen wie Deprivations- und Überlastungsgefühle, der Verlust von Angehörigen und Kriegsbeschädigungen „privatisiert“, d.h. an die Familien übertragen wurden. Dort seien dann in erster Linie die weiblichen Familienmitglieder mit der Versorgungs- und Pflegearbeit konfrontiert worden. An vier Fallbeispiele schließt sich eine detaillierte Auswertung des gesamten Interviewmaterials an. Diesen Teilen folgt ein Abschnitt zur staatlichen Kriegsopferversorgung in der frühen Bundesrepublik.

  1. A new von Mises probabilistic formula for quartet invariants

    International Nuclear Information System (INIS)

    Giacovazzo, C.; Camalli, M.; Spagna, R.

    1989-01-01

    Von Mises formulas for quartet invariants, even is useful in most cases of practical interest, suffer from some systematic errors. A new von Mises formula is suggested with better theoretical features. (orig.)

  2. Kerttu Wagner. Die historischen romane von Jaan Kross / Wolfgang Drechsler

    Index Scriptorium Estoniae

    Drechsler, Wolfgang, 1963-

    2001-01-01

    Arvustus: Wagner, Kerttu. Die historischen Romane von Jaan Kross : am Beispiel einer Untersuchung der deutschen und englischen Übersetzungen von "Professor Martensi ärasõit" (1984). Frankfurt am Main [etc.] : P. Lang, 2001.

  3. IAS 25, Bilanzierung von Finanzinvestitionen (Accounting for Investments)

    OpenAIRE

    Steiner, Manfred

    1997-01-01

    IAS 25, Bilanzierung von Finanzinvestitionen (Accounting for Investments). - In: Rechnungslegung nach International Accounting Standards (IAS) / hrsg. von Jörg Baetge ... - Stuttgart : Schäffer-Poeschel, 1997. - S. 923-953

  4. Borel reductibility and classification of von neumann algebras

    DEFF Research Database (Denmark)

    Sasyk, R.; Törnquist, Asger Dag

    2009-01-01

    We announce some new results regarding the classification problem for separable von Neumann algebras. Our results are obtained by applying the notion of Borel reducibility and Hjorth's theory of turbulence to the isomorphism relation for separable von Neumann algebras....

  5. Improving crack counterbalanced sucker rod pump units; Ueberlegungen zum dynamischen Drehmomentenausgleich von Tiefpumpenantrieben

    Energy Technology Data Exchange (ETDEWEB)

    Kessler, F. [Montanuniversitaet Leoben (Austria). Inst. fuer Konstruktionslehre

    1997-02-01

    Counterbalancing the torque at the gearbox, resulting from the load at the polished rod and the geometry of the unit, is still a significant design and operational problem. In this article well known crank-counterbalanced units are briefly described and a new unit, with an additional crank counterbalance system, is introduced. The counterweights on the cranks always create a sinusoidal torque distribution over one cycle. Applying the arithmetic method of non linear regression to the torque distribution, which results from the load at the polished rod, a most closely matching sinussoidal curve can be calculated. This curve shows the optimum phase angle and counterweight torque value and therefore a quick adjustment of the counterweights can be made. With the same arithmetic method, phase angle and counterweight value of the additional crank counterbalance is established. A comparison between a conventional unit and one with an additional counterbalancesystem has shown, that in the second case, the acting gearbox torque is up to 50% lower than in the first case. This allows the use of smaller gearbox and prime mover. From the technical point of view the additional counterbalance system is an excellent development enabling the acting-gearbox torque to be reduced. System set-up requires only a simple computer program and careful operator implementation. (orig.) [Deutsch] Der Ausgleich des zyklisch schwankenden Antriebsdrehmomentes stellt fuer die Auslegung und den Betrieb von Tiefpumpenantrieben ein zentrales Problem dar. In der vorliegenden Arbeit werden einleitend die bekannten Antriebsbauarten mit dynamischem Drehmomentenausgleich beschrieben und eine neue Bauart mit zusaetzlichem Ausgleich vorgestellt. Die Lasten am Pferdekopf verursachen an der Kurbel (Getriebeausgang) ein Drehmoment, das als Bruttodrehmoment bezeichnet wird. Das Ausgleichsdrehmoment zur Verringerung des Bruttodrehmomentes ist jenes Moment an der Kurbel, das durch die rotierenden

  6. Anwendung der extrakorporalen Stoßwellentherapie bei kalzifizierender Periathropathia humeroscapularis, Fersensporn und Epicondylitis humeri - Erfahrungsbericht aus dem Wilhelminenspital

    Directory of Open Access Journals (Sweden)

    Feyertag J

    2004-01-01

    Full Text Available Die Stoßwellentherapie wird bei verschiedenen Indikationen, die unter konservativen Therapien schwer zu schwer zu behandeln sind, eingesetzt. Dazu zählen die kalzifizierenden Schultererkrankungen (Tendinitis calcarea, Epicondylitis humeri (EHR und die plantare Fasciitis mit/ohne plantarem Fersensporn (FSP. Berichtet werden die Ergebnisse von 147 Patienten (102 Frauen/45 Männer, mittleres Alter betrug 57,8 Jahre, die mittels einer einmaligen extrakorporalen Stoßwellentherapie (ESWT (Tend. calc. 82 %, FSP 11 % oder EHR 7 % mittels eines HMT-ReflecTron therapiert wurden. Verabreicht wurden im Mittel 1.800 Stoßwellen. Untersucht wurde die subjektive Verbesserung der Schmerzen anhand einer visuellen Analogskala vor und 6 Wochen nach der Therapie bei allen Patienten. Bei Patienten mit Tendinitis calcarea wurde auch eine Verbesserung der Funktion sowie Veränderungen der Kalzifizierungen untersucht. Bei allen Patienten konnte eine statistisch signifikante Verbesserung der Schmerzen sowie des Bewegungsumfanges beobachtet werden (p 0,0001. Röntgenaufnahmen ergaben eine partielle Verkleinerung der Kalkdepots bei ca. 80 % der Patienten. Aufgrund der geringen Zahl der Patienten fand sich für die EHR keine signifikante Verbesserung der Schmerzsymptomatik. Eine einmalige ESWT kann zu einer deutlichen Verbesserung der Schmerzsymptomatik und zu einer Verbesserung des Bewegungsumfanges führen. Bei 80 % der Patienten mit einer Tendinitis calcarea findet sich weiter eine partielle Verkleinerung der Kalkdepots 6 Wochen nach Therapie.

  7. Medien und Berufsvorstellungen von Kindern: eine experimentelle Studie zum Einfluss von Kinderbüchern auf das Berufsspektrum von Kindergartenkindern

    OpenAIRE

    Brüggemann, Tim; Gehrau, Volker; Handrup, Jutta

    2015-01-01

    "Der Beitrag thematisiert zunächst den Stand der beruflichen Orientierung von Jugendlichen sowie die pädagogischen Bemühungen beim Übergang Schule-Beruf, insbesondere im Hinblick auf eine Erweiterung des häufig engen Spektrums von Berufen, die bei der Berufswahl berücksichtig werden. Dabei richten sich die Bestrebungen, diesem Problem entgegenzuwirken, bislang vor allem auf Jugendliche. Anschließend wird anhand vorliegender Ergebnisse aus der Medienforschung diskutiert, in welcher Weise Masse...

  8. Doença de von Willebrand e anestesia Enfermedad de von Willebrand y anestesia Von Willebrand's disease and anesthesia

    Directory of Open Access Journals (Sweden)

    Fabiano Timbó Barbosa

    2007-06-01

    Full Text Available JUSTIFICATIVA E OBJETIVOS: A doença de von Willebrand ocorre devido à mutação no cromossomo 12 e é caracterizada por deficiência qualitativa ou quantitativa do fator de von Willebrand. A diversidade de mutações leva ao aparecimento das mais variadas manifestações clínicas possibilitando a divisão dos pacientes em vários tipos e subtipos clínicos. A coagulopatia se manifesta basicamente através da disfunção plaquetária associada à diminuição dos níveis séricos do fator VIII coagulante. O objetivo dessa revisão foi mostrar os cuidados relacionados aos pacientes portadores da doença de von Willebrand durante o período perioperatório. CONTEÚDO: Foram definidas as características da doença de von Willebrand quanto à fisiopatologia, à classificação, ao diagnóstico laboratorial, ao tratamento atual e aos cuidados com o manuseio do paciente no período perioperatório. CONCLUSÕES: A doença de von Willebrand é o distúrbio hemorrágico hereditário mais comum, porém ela é subdiagnosticada pela complexidade da própria doença. A correta classificação do paciente, o uso apropriado da desmopressina e a transfusão do fator de von Willebrand são medidas fundamentais para a realização do procedimento anestésico bem-sucedido.JUSTIFICATIVA Y OBJETIVOS: La enfermedad de von Willebrand ocurre debido a la mutación en el cromosoma 12 y se caracteriza por la deficiencia cualitativa o cuantitativa del factor de von Willebrand. La diversidad de mutaciones conlleva al aparecimiento de las más variadas manifestaciones clínicas posibilitando la división de los pacientes en varios tipos y subtipos clínicos. La coagulopatía se manifiesta básicamente a través de la disfunción plaquetaria asociada con la disminución de los niveles séricos del factor VIII coagulante. El objetivo de esa revisión fue mostrar los cuidados relacionados con las pacientes portadoras de la enfermedad de von Willebrand durante el per

  9. Gemeinsam hilfreich oder einsam lästig? Beurteilung von praktikumsbegleitenden Weblogs von angehenden Lehrpersonen

    Directory of Open Access Journals (Sweden)

    Nives Egger

    2017-02-01

    Full Text Available Weblogs werden an Hochschulen vermehrt zur Unterstützung von Lern- und Reflexionsprozessen eingesetzt, in der Lehrer/innenbildung auch zunehmend während der berufspraktischen Ausbildung. Die Studierenden beurteilen den Einsatz von Weblogs jedoch unterschiedlich. Dabei ist wenig bekannt, welchen Einfluss die Vergabe und das Erhalten von Peerfeedback auf den Beurteilungsprozess von praktikumsbegleitenden Weblogs sowie auf den Umfang von Blogpostings haben. Im folgenden Beitrag wird dieser Frage mittels einer Befragung von 74 angehenden Lehrpersonen nachgegangen, die praktikumsbegleitende Weblogs mit oder ohne Peerfeedback nutzten, um über herausfordernde Ereignisse im Praktikum zu reflektieren. Die Ergebnisse zeigen, dass Studierende, die Peerfeedback erhielten und andere Blogbeiträge kommentierten, den Weblogeinsatz nützlicher einschätzen sowie eine höhere Motivation und positivere Einstellung gegenüber den Einsatz von Weblogs aufweisen als Studierende, die ohne Peerfeedback bloggen. Keinen Einfluss hat Peerfeedback auf den Umfang der Blogbeiträge und auf die dafür aufgewendete Zeit.

  10. Von Willebrand protein binds to extracellular matrices independently of collagen.

    OpenAIRE

    Wagner, D D; Urban-Pickering, M; Marder, V J

    1984-01-01

    Von Willebrand protein is present in the extracellular matrix of endothelial cells where it codistributes with fibronectin and types IV and V collagen. Bacterial collagenase digestion of endothelial cells removed fibrillar collagen, but the pattern of fibronectin and of von Willebrand protein remained undisturbed. Exogenous von Willebrand protein bound to matrices of different cells, whether rich or poor in collagen. von Willebrand protein also decorated the matrix of cells grown in the prese...

  11. The new law on radiation protection as a consequence of the EU safety standard of 2013; Das neue Strahlenschutzgesetz als Auswirkung der EU-Grundnormen von 2013

    Energy Technology Data Exchange (ETDEWEB)

    Layer, G. [Klinikum Ludwigshafen gGmbH, Zentralinstitut fuer Diagnostische und Interventionelle Radiologie, Ludwigshafen (Germany)

    2017-07-15

    europaeischen Richtlinie (2013/59/Euratom) aus dem Jahr 2013 in nationales Recht erfordert die Anpassung nationaler gesetzlicher Regularien. Alle Bereiche des Schutzes vor ionisierender Strahlung werden dieses Jahr systematisch mit dem neuen Strahlenschutzgesetz StrlSchG erfasst. Dadurch werden Roentgenverordnung und Strahlenschutzverordnung auf hoeherem Autoritaetsniveau zusammengefuehrt. Die Hauptteile des StrlSchG bekommen eine neue Systematik und gliedern nach Expositionssituation: Strahlenschutz bei geplanten Expositionssituationen, Strahlenschutz bei Notfallexpositionssituationen, Strahlenschutz bei bestehenden Expositionssituationen und expositionssituationsuebergreifende Vorschriften. Die fuer die Radiologie wichtigsten erstmals oder modifiziert geregelten Punkte betreffen die Frueherkennung, wo die Anwendung von Roentgen- oder radioaktiver Strahlung unter bestimmten Bedingungen prinzipiell erlaubt wird, das Hinzuziehen des Medizinphysikexperten bei allen strahlendiagnostischen Untersuchungsverfahren und interventionsradiologischen Anwendungen, die mit hohen Dosen der untersuchten Person verbunden sind, die Teleradiologie als weiterhin genehmigungsbeduerftiger Sonderfall der Anwendung von Roentgenstrahlung am Menschen, jetzt mit der erforderlichen Fachkunde im Strahlenschutz, vormals mit der Gesamtfachkunde sowie die Forschung mit Ersatz des vereinfachten Genehmigungsverfahrens durch ein Anzeigeverfahren. Weiterhin kann sich der Strahlenschutzbeauftragte im Konfliktfall im Gegensatz zu bisherigen Regelungen direkt an die Aufsichtsbehoerde wenden, was eine deutliche Staerkung seiner Autoritaet bedeutet. Der einzige Dosisgrenzwert, bei dem es zu einer deutlichen Absenkung kommen wird, ist die Organaequivalenzdosis der Augenlinse, deren Hoechstwert bei beruflich Strahlenexponierten von 150 auf 20 mSv pro Jahr herabgesetzt wird. (orig.)

  12. MR-Imaging optimisation of the articular hip cartilage by using a T{sub 1}-weighted 3-dimensional gradient-echo sequence and the application of a hip joint traction; Magnetresonanztomographische Optimierung der Hueftknorpeldarstellung durch die Wahl einer T{sub 1}-Volumen-Gradienten-Echo-Sequenz und die Anwendung einer Hueftgelenkstraktion

    Energy Technology Data Exchange (ETDEWEB)

    Rosenberg, R. [Heidelberg Univ. (Germany). Orthopaedische Klinik und Poliklinik; Bernd, L. [Heidelberg Univ. (Germany). Orthopaedische Klinik und Poliklinik; Wrazidlo, W. [ATOS-Praxisklinik, Heidelberg (Germany). Radiologische Gemeinschaftspraxis Drs. Lederer, Schneider und Wrazidlo; Lederer, W. [ATOS-Praxisklinik, Heidelberg (Germany). Radiologische Gemeinschaftspraxis Drs. Lederer, Schneider und Wrazidlo; Schneider, S. [ATOS-Praxisklinik, Heidelberg (Germany). Radiologische Gemeinschaftspraxis Drs. Lederer, Schneider und Wrazidlo

    1995-10-01

    Images of three animal cadaver hips, 8 dissected patient femoral heads and 18 hip joints of human corpses, all either with arthrosis stage I-III or artificial cartilage defects, were compared with their corresponding anatomic sections. Additional histomorphologic examinations of the arthrotic cartilages were conducted, and MR-Imaging of 20 healthy and 21 arthrotic patient hips was performed using a specific traction method. Using a T{sub 1}-weighted 3-dimensional gradient-echo sequence and a traction of the hip joint, it was possible due to the low-signal imaging of the joint space to separate in vivo the high-signal femoral head cartilage from the high-signal acetabular cartilage. In horizontal position of the phase-encoding parameter, minimisation of the chemical-shift artifact, mainly in the ventro-lateral areas, was accomplished. MRI measurements of the articular cartilage widths showed significant correlations (p < 0.001) with the corresponding anatomic sections. At the same time the T{sub 1} 3-dimensional gradient-echo sequence of the lateral femoral head with r = 0.94 showed the lowest deviations of the measurements. It was possible with MR-Imaging to distinguish four cartilage qualities. (orig./MG) [Deutsch] Im experimentellen Teil der Studie wurden den MRT-Bildern von drei Kadavertierhueften, 8 resezierten Patientenhueftkoepfen und 18 Leichenhueftgelenken, an denen entweder artifizielle Knorpeldefekte gesetzt wurden oder die ein Koxarthrose-Stadium I-III aufwiesen, die korrespondierenden makroskopischen Kryomikrotomschnitte zugeordnet. Bei den Koxarthrosen erfolgten zusaetzliche histomorphologische Knorpeluntersuchungen. Im klinischen Teil der Studie wurden 20 gesunde und 21 arthrotische Probandenhueftgelenke mit einem speziellen Traktionsverfahren untersucht. Unter Anwendung einer T{sub 1}-Volumen-Gradienten-Echo-Sequenz und einer Traktion am zu untersuchenden Hueftgelenk konnte in vivo durch die signalarme Darstellung des Gelenkspaltes der

  13. Extraskeletal primary Ewing's scrcoma in the nasal cavity: A case report

    International Nuclear Information System (INIS)

    Jeong, Bo Young; Park, Seok Won; Km, Eo Jin; Choi, Jong Sun; Lee, Eun Ja

    2013-01-01

    Ewing's sarcoma presents a rare tumor of the head and neck, and even rarer in the nasal cavity and/or paranasal sinuses. We report the case of Ewing's sarcoma in the nasal cavity, as presented with nasal obstruction and epistaxis. The CT and MRI examination reveals a mass in the left nasal cavity with extension to contralateral side, ethmoidal sinus, and nasopharynx. We provide an overview of Ewing's sarcoma in the nasal cavity and discuss radiologic findings of this unusual case.

  14. [Anja Wilhelmi. Lebensweltlen von Frauen der deutschen Oberschicht im Baltikum (1800-1939). Eine Untersuchung anhand von Autobiographien] / Alexander Ewig

    Index Scriptorium Estoniae

    Ewig, Alexander, 1980-

    2011-01-01

    Arvustus: Wilhelmi, Anja. Lebenswelten von Frauen der deutschen Oberschicht im Baltikum (1800-1939). Eine Untersuchung anhand von Autobiographien. (Veröffentlichungen des Nordost-Instituts, 10.) (Wiesbaden : HArrassowitz 2008)

  15. Angioleiomyoma of nasal septum: Case report and literature review

    Directory of Open Access Journals (Sweden)

    Varun V. Varadarajan, M.D.

    2016-12-01

    Conclusion: Angioleiomyoma of the nasal septum is a rare and challenging clinical diagnosis that requires detailed histopathologic examination. The differential diagnosis includes a variety of epithelial and mesenchymal derived tumors. Literature review suggests a female predilection with possible hormonal influence.

  16. Nasal septum perforation in patient with pyoderma gangrenosum

    Directory of Open Access Journals (Sweden)

    Maia, Camilla Bezerra da Cruz

    2012-01-01

    Full Text Available Introduction: The cocaine is obtained from the leaves of the coca (Erythroxylon coca. It can be used in many ways, but the most common is the drug inhalation. The Cocaine also causes vasoconstriction at nasal mucous membrane and its chronic use can cause necrosis and nasal septum perforation. Pyoderma gangrenosum is an uncommon idiopathic disease characterized by ulcerations, usually observed on the legs. Its diagnosis is most common an exclusion of others diseases. So far, there is no specific treatment based on evidence by randomized controlled trials. Objective: Describe the rare association between Pyoderma gangrenosum and cocaine. Case Report: E. A., 27-year-old woman with destruction of nasal septum and palate who has been using a big amount of cocaine, been necessary note the difference from which disease cause de damage. Final Comments: Also there are only three cases of Pyoderma gangrenosum complicated with nasal septum perforation in cocaine users.

  17. Reconstruction of the nasal septum using polydioxanone plate

    NARCIS (Netherlands)

    Boenisch, Miriam; Nolst Trenité, Gilbert J.

    2010-01-01

    To evaluate the usefulness of resorbable polydioxanone plate attached to nasal septal cartilage in external septoplasty, to assess its mechanical stability until healing of cartilage fragments, and to describe the surgical technique and clinical experience. External septoplasty with polydioxanone

  18. Psychological, Functional and Aesthetic Outcome after Nasal Reconstruction

    NARCIS (Netherlands)

    S.E. Moolenburgh (Sanne)

    2009-01-01

    markdownabstract__Abstract__ The incidence of nasal skin malignancies is increasing worldwide rapidly. As a result of the surgical treatment of these malignancies the demand for reconstructive procedures has also increased enormously. In literature, emphasis exists on technical refinements to

  19. Extra-skeletal Ewing's sarcoma of the nasal fossa.

    Science.gov (United States)

    Lane, S; Ironside, J W

    1990-07-01

    Extraskeletal Ewing's sarcoma is rarely found arising in the head and neck region. An unusual case arising in the nasal fossa in a young child is reported and the differential diagnosis, pathology and treatment discussed.

  20. Early surfactant therapy and nasal continuous positive airways ...

    African Journals Online (AJOL)

    respiratory distress syndrome (RDS) receiving nasal continuous positive airways ... required FiO2 was allowed to rise above 0.4 before surfactant was administered. ... group received surfactant immediately and the high-threshold group ...

  1. Mechanics of airflow in the human nasal airways.

    Science.gov (United States)

    Doorly, D J; Taylor, D J; Schroter, R C

    2008-11-30

    The mechanics of airflow in the human nasal airways is reviewed, drawing on the findings of experimental and computational model studies. Modelling inevitably requires simplifications and assumptions, particularly given the complexity of the nasal airways. The processes entailed in modelling the nasal airways (from defining the model, to its production and, finally, validating the results) is critically examined, both for physical models and for computational simulations. Uncertainty still surrounds the appropriateness of the various assumptions made in modelling, particularly with regard to the nature of flow. New results are presented in which high-speed particle image velocimetry (PIV) and direct numerical simulation are applied to investigate the development of flow instability in the nasal cavity. These illustrate some of the improved capabilities afforded by technological developments for future model studies. The need for further improvements in characterising airway geometry and flow together with promising new methods are briefly discussed.

  2. Rhinoscintigraphic analysis of nasal mucociliary function in patients ...

    African Journals Online (AJOL)

    2015-11-02

    Nov 2, 2015 ... renal failure, liver disorders or hypo/hyperthyroidism, use of any topical or systemic drugs that could affect nasal physiology (topical or oral decongestants, antihypertensives, ..... Anatomy of the Nose and Paranasal Sinuses.

  3. Zicam-induced damage to mouse and human nasal tissue.

    Directory of Open Access Journals (Sweden)

    Jae H Lim

    Full Text Available Intranasal medications are used to treat various nasal disorders. However, their effects on olfaction remain unknown. Zicam (zinc gluconate; Matrixx Initiatives, Inc, a homeopathic substance marketed to alleviate cold symptoms, has been implicated in olfactory dysfunction. Here, we investigated Zicam and several common intranasal agents for their effects on olfactory function. Zicam was the only substance that showed significant cytotoxicity in both mouse and human nasal tissue. Specifically, Zicam-treated mice had disrupted sensitivity of olfactory sensory neurons to odorant stimulation and were unable to detect novel odorants in behavioral testing. These findings were long-term as no recovery of function was observed after two months. Finally, human nasal explants treated with Zicam displayed significantly elevated extracellular lactate dehydrogenase levels compared to saline-treated controls, suggesting severe necrosis that was confirmed on histology. Our results demonstrate that Zicam use could irreversibly damage mouse and human nasal tissue and may lead to significant smell dysfunction.

  4. Nasal Aspergillosis in a Dog: A Case Report

    Directory of Open Access Journals (Sweden)

    Camilo Padilla Peñuela

    2014-07-01

    Full Text Available Nasal aspergillosis is a major chronic disease affecting the nostrils in dogs. Clinical sinology is typical in every chronic nasal disease. Epistaxis and occasional pain occurs. Rhinoscopic assessment of the area evidences findings associated with the pathology and allows collecting samples for cytology and culture. Systemic therapy with oral antifungals has had variable utility, but now it has been replaced by direct topical medication to the affected area. This article describes the case of a 4-years-old male dog, submitted to consultation by unilateral muco-bloody nasal discharge with a week of evolution. The patient was treated by another vet center with cyclonamine and vitamin K for a possible clotting disorder. After a series of tests that included rhinoscopy and fungal culture, nasal aspergillosis was diagnosed. Intranasal clotrimazole was applied twice and it allowed the resolution of the clinical signs.

  5. Inducible clindamycin resistance and nasal carriage rates of ...

    African Journals Online (AJOL)

    Conclusion: MRSA nasal carriage among healthcare workers needs infection control practice in hospitals to prevent trans- ... infection and is becoming an increasing problem among ..... ated risk factors and pulsed field gel electrophoresis of.

  6. Gasification of liquid manure; Vergasung von Guelle

    Energy Technology Data Exchange (ETDEWEB)

    Gudenau, H.W.; Hoberg, H.; Hirsch, U. [Technische Hochschule Aachen (Germany). Inst. fuer Eisenhuettenkunde

    1996-12-31

    The potential of thermal use of liquid manure is investigated. It is recommended to separate the liquid and solid fraction. While the liquid fraction can be used as fertilizer, the solid fraction can be used for generating a fuel gas for combined heat and power generation. (orig) [Deutsch] Die Untersuchungen haben ergeben, dass in der thermischen Verwertung von Guelle ein bisher nur wenig genutztes Potential vorliegt. Die zum Anbau von Getreide notwendige Duengung kann durch Separation von Guelle in Fest- und Duennfraktion effektiver und kostenguenstiger durchgefuehrt werden. Der Naehrstoffgehalt des Guellefeststoffs sollte durch thermische Aufbereitung aufkonzentriert werden, so dass eine Vermarktung auch mit laengeren Transpoertwegen darstellbar ist. Die bei der thermischen Behandlung gewonnene Waerme kann prozessintern genutzt und ueberschuessige Waerme an Abnehmer in der naeheren Umgebung geliefert werden. Genauso besteht die Moeglichkeit, ein Brenngas zu erzeugen und die Energie mit Kraft-Waerme-Kopplung zu nutzen. (orig)

  7. Gasification of liquid manure; Vergasung von Guelle

    Energy Technology Data Exchange (ETDEWEB)

    Gudenau, H W; Hoberg, H; Hirsch, U [Technische Hochschule Aachen (Germany). Inst. fuer Eisenhuettenkunde

    1997-12-31

    The potential of thermal use of liquid manure is investigated. It is recommended to separate the liquid and solid fraction. While the liquid fraction can be used as fertilizer, the solid fraction can be used for generating a fuel gas for combined heat and power generation. (orig) [Deutsch] Die Untersuchungen haben ergeben, dass in der thermischen Verwertung von Guelle ein bisher nur wenig genutztes Potential vorliegt. Die zum Anbau von Getreide notwendige Duengung kann durch Separation von Guelle in Fest- und Duennfraktion effektiver und kostenguenstiger durchgefuehrt werden. Der Naehrstoffgehalt des Guellefeststoffs sollte durch thermische Aufbereitung aufkonzentriert werden, so dass eine Vermarktung auch mit laengeren Transpoertwegen darstellbar ist. Die bei der thermischen Behandlung gewonnene Waerme kann prozessintern genutzt und ueberschuessige Waerme an Abnehmer in der naeheren Umgebung geliefert werden. Genauso besteht die Moeglichkeit, ein Brenngas zu erzeugen und die Energie mit Kraft-Waerme-Kopplung zu nutzen. (orig)

  8. Spectral theory and quotients in Von Neumann algebras | West ...

    African Journals Online (AJOL)

    In this note we consider to what extent the functional calculus and the spectral theory in von Neumann algebras are preserved by the taking of quotients relative to two-sided ideals of the von Neumann algebra. Keywords:von Neumann algebra, functional calculus, spectral theory, quotient algebras. Quaestiones ...

  9. Anatomy and Surgical Approaches to the Rabbit Nasal Septum.

    Science.gov (United States)

    Badran, Karam W; Chang, John C; Kuan, Edward C; Wong, Brian J F

    2017-09-01

    The rabbit is the primary animal model used to investigate aspects of nasal surgery. Although several studies have used this model, none has provided a comprehensive analysis of the surgical anatomy and techniques used to gain access to the rabbit nasal fossae and septum. To describe and optimize the surgical anatomy and approach to the rabbit nasal vault and septal cartilage. In an ex vivo animal study conducted at an academic medical center, preliminary cadaveric dissections were performed on rabbit head specimens to establish familiarity with relevant anatomy and rehearse various approaches. Live Pasteurella-free New Zealand white rabbits (3.5-4.0 kg) were used to further develop this surgical technique developed here. Access of the nasal vault was gained through a midline nasal dorsum incision and creation of an osteoplastic flap with a drill. Submucosal resection was performed with preservation of the mucoperichondrium. All rabbits were monitored daily for 4 weeks in the postoperative period for signs of infection, pain, and complications. The study was conducted from June 1, 2014, to December 1, 2014. Surgical anatomy and techniques used to gain access to the rabbit nasal vault and harvest septal cartilage. Four Pasteurella-free New Zealand white rabbits (Western Organ Rabbit Co), ranging in age from 9 to 12 months and weighing between 3.5 and 4.0 kg, were used in this study. Initial dissections demonstrated the feasibility of harvesting septal cartilage while preserving the mucoperichondrial envelope. Access to the nasal vault through this 3-osteotomy approach allowed for maximal exposure to the nasal cavity bilaterally while maintaining the integrity of the mucoperichondrium following septal cartilage harvest. The maximum amount of bulk, en bloc, cartilage harvested was 1.0 × 2.5 cm. Following surgical dissection, all animals maintained adequate airway patency and support to midface structures. Furthermore, all specimens preserved the integrity of the

  10. Midline nasal dermoid cyst with Tessier's 0 cleft

    OpenAIRE

    Guruprasad, Yadavalli; Chauhan, Dinesh Singh

    2014-01-01

    This is a rare anomaly of midline nasal dermoid cyst (NDC) along with Tessier's 0 cleft. Midline NDCs present most commonly result from aberrant embryological development, and most commonly give rise to bifid nasal deformity resulting in midline cleft of the nose. Craniofacial clefts are among the most disfiguring of all facial anomalies. They exist in a multitude of patterns and with varying degrees of severity. The bifid nose deformity is generally an indicator of Tessier number 0 cleft. We...

  11. Effect of nasal deviation on quality of life.

    Science.gov (United States)

    de Lima Ramos, Sueli; Hochman, Bernardo; Gomes, Heitor Carvalho; Abla, Luiz Eduardo Felipe; Veiga, Daniela Francescato; Juliano, Yara; Dini, Gal Moreira; Ferreira, Lydia Masako

    2011-07-01

    Nasal deviation is a common complaint in otorhinolaryngology and plastic surgery. This condition not only causes impairment of nasal function but also affects quality of life, leading to psychological distress. The subjective assessment of quality of life, as an important aspect of outcomes research, has received increasing attention in recent decades. Quality of life is measured using standardized questionnaires that have been tested for reliability, validity, and sensitivity. The aim of this study was to evaluate health-related quality of life, self-esteem, and depression in patients with nasal deviation. Sixty patients were selected for the study. Patients with nasal deviation (n = 32) were assigned to the study group, and patients without nasal deviation (n = 28) were assigned to the control group. The diagnosis of nasal deviation was made by digital photogrammetry. Quality of life was assessed using the Medical Outcomes Study 36-Item Short Form Health Survey questionnaire; the Rosenberg Self-Esteem/Federal University of São Paulo, Escola Paulista de Medicina Scale; and the 20-item Self-Report Questionnaire. There were significant differences between groups in the physical functioning and general health subscales of the Medical Outcomes Study 36-Item Short Form Health Survey (p < 0.05). Depression was detected in 11 patients (34.4 percent) in the study group and in two patients in the control group, with a significant difference between groups (p < 0.05). Nasal deviation is an aspect of rhinoplasty of which the surgeon should be aware so that proper psychological diagnosis can be made and suitable treatment can be planned because psychologically the patients with nasal deviation have significantly worse quality of life and are more prone to depression. Risk, II.(Figure is included in full-text article.).

  12. Alcohol hyper-responsiveness in chronic rhinosinusitis with nasal polyps.

    Science.gov (United States)

    De Schryver, Els; Derycke, Lara; Campo, Paloma; Gabriels, Eline; Joos, Guy F; Van Zele, Thibaut; Bachert, Claus; Hellings, Peter W; Gevaert, Philippe

    2017-02-01

    An important percentage of subjects diagnosed with chronic upper airway disease report alcohol-induced worsening of their symptoms. The prevalence and characteristics of respiratory reactions provoked by alcohol-containing drinks have not been fully investigated yet. The aim of this study was to estimate the prevalence and characteristics of alcohol hyper-responsiveness in patients with chronic airway disease and healthy controls. Furthermore, nasal inflammation was evaluated in nasal polyp patients with and without hyper-responsiveness. We evaluated the prevalence and characteristics of alcohol-induced respiratory complaints in 1281 subjects. Chronic rhinosinusitis with nasal polyps (CRSwNP) patients with and without NSAID exacerbated respiratory disease (NERD), chronic rhinosinusitis patients without nasal polyps (CRSsNP), allergic rhinitis (AR) patients and healthy controls were approached by means of a questionnaire. Inflammatory markers (eosinophilic cationic protein (ECP), IL-5, IgE, SAE-specific IgE, IL-17, TNFα and IFNγ) in tissue were then compared between alcohol hyper-responsive and non-hyper-responsive CRSwNP patients. The highest prevalence of nasal and bronchial alcohol hyper-responsiveness was observed in patients with NERD, followed by CRSwNP, and less frequent in CRSsNP, AR and healthy controls. Alcohol hyper-responsiveness is significantly more prevalent in CRSwNP patients suffering from recurrent disease and in patients with severe symptomatology. In nasal tissue of the hyper-responsive CRSwNP group, we observed significantly higher nasal levels of the eosinophilic biomarker ECP. Nasal hyper-responsiveness to alcohol is significantly more prevalent in severe eosinophilic upper airway disease. © 2016 John Wiley & Sons Ltd.

  13. Polyvinyl siloxane: novel material for external nasal splinting.

    Science.gov (United States)

    Jayakumar, N K; Rathnaprabhu, V; Ramesh, S; Parameswaran, A

    2016-01-01

    External nasal splinting is performed routinely after nasal bone fracture reductions, osteotomies, and rhinoplasties. Materials commonly used include plaster of Paris (POP), thermoplastic splints, self-adhesive padded aluminium splints, and Orthoplast, among many others. The disadvantages of these materials are described in this paper, and polyvinyl siloxane is recommended as an effective and more readily available alternative material to counter these pitfalls. Copyright © 2015 International Association of Oral and Maxillofacial Surgeons. Published by Elsevier Ltd. All rights reserved.

  14. Paradoxical sensation of nasal airflow in patients with common cold. Are we measuring the correct modality?

    Science.gov (United States)

    Clarke, Jonathan D; Eccles, Ronald

    2005-12-01

    A paradoxical relationship between objective and subjective measures of nasal obstruction exists in participants not exposed to any treatment. The sensation of nasal obstruction may be due to the amalgamation of many different nasal sensations. Improved methods for measuring nasal sensations are required to further investigate the relationship between objective and subjective measures of nasal obstruction. In a recent study it was shown that the subjective sensation of nasal patency increased as the nasal passages became objectively more obstructed in patients who received a placebo compared to those who received an oral decongestant. This paradoxical response may be explained as a placebo effect, i.e. patients who received a placebo may have expected to feel less obstructed. The aim of the present study was to investigate this interesting paradox by determining objective and subjective measures of nasal obstruction over time in participants not exposed to any treatment. A total of 60 healthy participants with common cold were recruited. Objective and subjective measures of nasal obstruction were recorded at baseline and at 1 and 2 h using posterior rhinomanometry and a visual analogue scale. Objective measures demonstrated an increase in nasal obstruction over time for both nasal passages considered together and for individual nasal passages. Subjective measures demonstrated a sensation of decreased nasal obstruction over time for both nasal passages considered together and for individual nasal passages.

  15. Der Einfluss von sozialer Ungleichheit und kulturellen Unterschieden auf die Wahrnehmung von finanziellen und Arbeitsplatzrisiken: Überlegungen zur Risikogesellschaft

    OpenAIRE

    Abbott, David; Quilgars, Deborah; Jones, Anwen

    2006-01-01

    Der vorliegende Artikel beruht auf Daten einer Studie, die sich mit der Frage beschäftigt, wie verschiedene soziale und kulturelle Gruppen die Risiken von Einkommens- und Arbeitsplatzverlust wahrnehmen und darauf reagieren. Autoren wie LASH, DOUGLAS und LUPTON betonten die Bedeutung von Gruppenzugehörigkeit und sozialen Kategorien für die Strukturierung der Reaktionsweisen auf verschiedene Risikoarten. Sie sprechen daher lieber von Risikokulturen als von der Risikogesellschaft. Trotzdem erken...

  16. Bewertung von Fahrzeuggeräuschen

    Science.gov (United States)

    Genuit, Klaus; Schulte-Fortkamp, Brigitte; Fiebig, André; Haverkamp, Michael

    Bei der Wahrnehmung und Beurteilung eines Automobils sind unzählige Merkmale und Eigenschaften von Bedeutung. Dabei können Merkmale objektiv-technisch beschrieben werden, wie Angaben zur Motorisierung, Höchstgeschwindigkeit, Drehmoment, zulässige Zuladung, Verbrauch usw. Daneben sind weitere Eigenschaften von Bedeutung, die sich einer einfachen objektiv-technischen Beschreibung entziehen. Hier sind Begriffe zu nennen, wie Sicherheit, allgemeine Qualitätsanmutung, Design, Ergonomie, Komfort, Haptik, Fahrdynamik, Zuverlässigkeit, die deutlich schwieriger objektiv erfassbar und beschreibbar sind (Abb. 4.1).

  17. Asymptotic analysis of a von Koch beam

    International Nuclear Information System (INIS)

    Carpinteri, Alberto; Pugno, Nicola; Sapora, Alberto

    2009-01-01

    Fractal geometry is used in diverse research areas, being an useful tool in describing the mechanical behaviour of natural and man-made structures. In this paper, the structural behaviour of a von Koch cantilever beam is analyzed in the small deformations regime. Analytical recursive formulae for the strain energy scaling are derived, which have been found in good agreement with numerical simulations. Energy considerations suggest a peculiar scaling for the beam rigidity in order to prevent compliance divergence. The results are then extended to evaluate the stiffness matrix of a von Koch beam.

  18. Von Mumien, Cyborgs und Röntgenbildern

    Directory of Open Access Journals (Sweden)

    Regina Schleicher

    2004-03-01

    Full Text Available Unter dem Titel Techniken der Reproduktion liegt ein Sammelband vor, der die Beiträge einer Tagung an der Universität Paderborn vom Dezember 2001 enthält. In enger Verknüpfung verschiedener disziplinärer Perspektiven werden Schlaglichter auf eine Vielzahl von Themen geworfen, die sich mit dem Begriff „Reproduktion“ verbinden. Dabei wird deutlich, wie eng die Geschichte der Medien und die Entwicklung von Technologien der biologischen Fortpflanzung miteinander verzahnt sind.

  19. Duration of Nasal Packs in the Management of Epistaxis

    International Nuclear Information System (INIS)

    Kundi, N. A.; Raza, M.

    2015-01-01

    Objective:To compare the efficacy of nasal packs for 12 and 24 hours in the management of epistaxis. Study Design: Quasi experimental study. Place and Duration of Study: Combined Military Hospital, Nowshera and Heavy Industries Taxilla Hospital, from October 2012 to April 2013. Methodology: A total of 60 patients presenting with epistaxis were selected and were divided into two groups of 30 patients each. Patients in both the groups were managed by nasal packs. In group-A packs were removed after 12 hours while in group-B after 24 hours. Symptoms of headache, lacrimation and recurrence of bleeding were recorded. SPSS 20 was used for data analysis and p-value less than 0.01 was considered significant. Results: There was significant difference for headache between removal of nasal packs after 12 hours and 24 hours (p < 0.001). There was significant difference for excessive lacrimation at 12 and 24 hours (p = 0.001). No significant difference was observed for recurrence of bleed when nasal packs were removed at 12 and 24 hours (p = 0.317). Conclusion: Duration in removal of nasal packs after 12 or 24 hours made a difference in the management of epistaxis. Symptoms of headache and excessive lacrimation were significantly higher when nasal packs were removed after 24 hours. It is recommended that patient could be managed with lesser duration of packs after episode of epistaxis to avoid inconvenience. (author)

  20. Application of direct digital radiography of nasal bone

    International Nuclear Information System (INIS)

    Gao Dengfa; Wang Haijun; Zhang Ailian; Wang Yulin

    2005-01-01

    Objective: To research the application value of direct digital radiograph (DDR ) in nasal bone imaging. Methods: One hundred cases were examined by DDR, 30 cases of them were examined by two methods both DDR and conventional radiography. All digital images were post-processed with 'MUSICA' (Multi-Scale Image Contrast Amplification), incision and largamente, analyzed and diagnosed by experienced two radiologists and two technicians. Results: One hundred cases of nasal bone, soft tissue of nose were showed excellent in DDR, and satisfactory cases were 95 and 92, respectively. Forty-six cases of nasal bone fractures were found. Thirty cases were examined by both DDR and conventional radiography, images of nasal bone, soft tissue of nose were showed, satisfactory cases were 28 in DDR; and satisfactory cases were 6 (χ 2 =20.05, P 2 =15.06, P 2 =5.14, P<0.05) in conventional and digital radiography, respectively. Conclusion: DDR images of nasal bone, soft tissue of nose was excellent, more fractures were discovered than conventional radiography. Image quality of DDR is better than conventional radiography in nasal bone imaging. (authors)

  1. Nasal mucosal blood flow after intranasal allergen challenge

    International Nuclear Information System (INIS)

    Holmberg, K.; Bake, B.; Pipkorn, U.

    1988-01-01

    The nasal mucosal blood flow in patients with allergic rhinitis was determined at nasal allergen challenges with the 133 Xenon washout method. Determinations were made in 12 subjects before and 15 minutes after challenge with diluent and increasing doses of allergen. The time course was followed in eight subjects by means of repeated measurements during 1 hour after a single allergen dose. Finally, the blood flow was measured after unilateral allergen challenge in the contralateral nasal cavity. A dose-dependent decrease in blood flow was found after nasal challenge with increasing doses of allergens, whereas challenge with diluent alone did not induce any changes. The highest allergen dose, which also induced pronounced nasal symptoms, resulted in a decrease in blood flow of 25% (p less than 0.001). The time-course study demonstrated a maximum decrease in blood flow 10 to 20 minutes after challenge and then a gradual return to baseline. Unilateral allergen challenge resulted in a decrease in blood flow in the contralateral, unchallenged nasal cavity, suggesting that part of the allergen-induced changes in blood flow were reflex mediated

  2. Control of nasal vasculature and airflow resistance in the dog.

    Science.gov (United States)

    Lung, M A; Phipps, R J; Wang, J C; Widdicombe, J G

    1984-01-01

    Nasal vascular and airflow resistances have been measured in dogs, simultaneously on both sides separately. Vascular resistance was measured either by constant flow perfusion of the terminal branch of the maxillary artery (which supplies, via the sphenopalatine artery, the nasal septum, most of the turbinates and the nasal sinuses) or by measuring blood flow through this artery, maintained by the dog's own blood pressure. Airflow resistance was assessed by inserting balloon-tipped endotracheal catheters into the back of each nasal cavity via the nasopharynx, and measuring transnasal pressure at constant airflow through each side of the nose simultaneously. Preliminary experiments indicated that there was 5-10% collateral anastomosis between the two sides. Close-arterial injection of drugs showed different patterns of response. Adrenaline, phenylephrine, chlorpheniramine and low doses of prostaglandin F2 alpha increased vascular resistance and lowered airway resistance. Salbutamol, methacholine and histamine lowered vascular resistance and increased airway resistance. Dobutamine decreased airway resistance with a small increase in vascular resistance. Prostaglandins E1, E2 and F2 alpha (high dose) decreased both vascular and airway resistances. Substance P, eledoisin-related peptide and vasoactive intestinal polypeptide lowered vascular resistance with little change in airway resistance. The results are interpreted in terms of possible drug actions on precapillary resistance vessels, sinusoids and venules, and arteriovenous anastomoses. It is concluded that nasal airway resistance cannot be correlated with vascular resistance or blood flow, since the latter has a complex and ill-defined relationship with nasal vascular blood volume. PMID:6204040

  3. Nasal reaction to changes in whole body temperature.

    Science.gov (United States)

    Lundqvist, G R; Pedersen, O F; Hilberg, O; Nielsen, B

    1993-11-01

    The changes in nasal patency following a 1.5 degrees C decrease or increase in whole body temperature were measured in 8 healthy young males, during and after 30 min of immersion in a 15 degrees C cold or a 40 degrees C warm bath, breathing air at the same temperature, in a cross-over experimental design. The nasal reactions were traced by consecutive measurements of changes in nasal cavity volumes by acoustic rhinometry. Swelling of the mucosa during cooling and an almost maximal shrinkage of the mucosa during heating were indicated by respectively a decrease and an increase in nasal cavity volumes. The reactions were determined predominantly by the whole body thermal balance, but were also influenced by the temperature of the inhaled air, either enhanced, reduced or temporarily reversed. The greatest change occurred in the nasal cavity, left or right, which differed most from the final state at the beginning of exposure due to the actual state of nasal cycle.

  4. Routine use of humidification with nasal continuous positive airway pressure.

    Science.gov (United States)

    Worsnop, C J; Miseski, S; Rochford, P D

    2010-09-01

    Heated humidification can reduce nasal symptoms caused by continuous positive airway pressure (CPAP) treatment, but its routine use has not been studied over the medium term in a randomized controlled trial. The aim of this study is to determine if heated humidification would reduce nasal symptoms and improve adherence with CPAP treatment in all patients with sleep apnoea irrespective of whether they had nasal symptoms initially. A randomized, parallel group design. Patients were treated for 3 months with a Fisher & Paykel HC201 pump with built-in heated humidification, or with the heater disabled and without water. Adherence was measured with a timer built into the pumps. Nasal symptoms were measured with a 10-cm visual analogue scale. There were 25 in the humidification group and 29 in the non-humidification group. After 12 weeks mean (standard deviation) adherence with CPAP was 4.7 (2.4) and 4.5 (2.2) hours per night respectively. Nasal symptoms that were reduced were nose blocked* 6 (12), 18 (26); sneezing* 4 (8), 15 (25); dry nose* 8 (12), 24 (33); stuffy nose* 7 (14), 22(31); dry mouth* 13 (18), 33(36); and runny nose* 6 (17), 14 (29). Parameters marked with an asterisk '*' had P humidification with CPAP in all patients with sleep apnoea reduced nasal symptoms, but did not improve adherence. © 2010 The Authors. Internal Medicine Journal © 2010 Royal Australasian College of Physicians.

  5. Nasalance and nasality at experimental velopharyngeal openings in palatal prosthesis: a case study

    Science.gov (United States)

    LIMA-GREGIO, Aveliny Mantovan; MARINO, Viviane Cristina de Castro; PEGORARO-KROOK, Maria Inês; BARBOSA, Plinio Almeida; AFERRI, Homero Carneiro; DUTKA, Jeniffer de Cassia Rillo

    2011-01-01

    The use of prosthetic devices for correction of velopharyngeal insufficiency (VPI) is an alternative treatment for patients with conditions that preclude surgery and for those individuals with a hypofunctional velopharynx (HV) with a poor prognosis for the surgical repair of VPI. Understanding the role and measuring the outcome of prosthetic treatment of velopharyngeal dysfunction requires the use of tools that allow for documenting pre- and post-treatment outcomes. Experimental openings in speech bulbs have been used for simulating VPI in studies documenting changes in aerodynamic, acoustic and kinematics aspects of speech associated with the use of palatal prosthetic devices. The use of nasometry to document changes in speech associated with experimental openings in speech bulbs, however, has not been described in the literature. Objective This single-subject study investigated nasalance and nasality at the presence of experimental openings drilled through the speech bulb of a patient with HV. Material and Methods Nasometric recordings of the word "pato" were obtained under 4 velopharyngeal conditions: no-opening (control condition), no speech bulb, speech bulb with a 20 mm2 opening, and speech bulb with 30 mm2 opening. Five speech-language pathologists performed auditory-perceptual ratings while the subject read an oral passage under all conditions. Results Kruskal-Wallis test showed significant difference among conditions (p=0.0002), with Scheffé post hoc test indicating difference from the no-opening condition. Conclusion The changes in nasalance observed after drilling holes of known sizes in a speech bulb suggest that nasometry reflect changes in transfer of sound energy related to different sizes of velopharyngeal opening. PMID:22230996

  6. Die Verteilung und Eigenschaften von Bodenformen in der Deutschen Bucht, eine Rekonstruktion der Karten von Ulrich (1973)

    DEFF Research Database (Denmark)

    Winter, Christian; Lefebvre, Alice; Benninghoff, Markus

    2015-01-01

    Entstehung, Gestalt und Dynamik von Bodenformen in vergleichsweise kleinen Untersuchungsgebieten ist die Arbeit von ULRICH (1973) über die Verteilung von Bodenformen in der Deutschen Bucht bis heute die einzige verfügbare zusammenhängende Darstellung für die deutsche Nordseeküste. Die analogen Karten und die...

  7. [Pyodermatitis-pyostomatitis vegetans with nasal involvement].

    Science.gov (United States)

    Peuvrel, L; Barbarot, S; Gagey-Caron, V; Tessier, M-H; Cassagnau, E; Stalder, J-F

    2008-11-01

    Pyodermatitis-pyostomatitis vegetans (PPV) is a rare chronic disorder often associated with inflammatory bowel disease. We report an isolated case involving the oral, labial and nasal mucosa. A 28-year-old man, in good general condition, presented with a 2-year history of painless stomatitis. The physical examination revealed pustular and exophytic lesions of the jugal, gingival and palatine mucosa on an erythematous background, as well as some pustular and crusted lesions of the lower lip and nostrils. Histopathological analysis revealed epithelial hyperplasia and a suprabasal cleft with some signs of acantholysis and numerous neutrophils and eosinophils. Direct and indirect immunofluorescence assay was negative. There was no associated bowel disease. We concluded on a diagnosis of PPV of younger subjects. The lesions disappeared with oral corticosteroids but with steroid dependency. PPV is a rare dermatosis associated in more than 75% of cases with inflammatory bowel disease, usually ulcerative colitis. Lesions of the oral mucosa are a constant finding and are characterised by aseptic pustules on an erythematous background. Skin lesions are pustular and more or less exophytic. To our knowledge, there have been no reports to date of intranasal lesions of PPV.

  8. Optical properties of nasal septum cartilage

    Science.gov (United States)

    Bagratashvili, Nodar V.; Sviridov, Alexander P.; Sobol, Emil N.; Kitai, Moishe S.

    1998-05-01

    Optical parameters (scattering coefficient s, absorption coefficient k and scattering anisotropy coefficient g) of hyaline cartilage were studied for the first time. Optical properties of human and pig nasal septum cartilage, and of bovine ear cartilage were examined using a spectrophotometer with an integrating sphere, and an Optical Multi-Channel Analyser. We measured total transmission Tt, total reflection Rt, and on-axis transmission Ta for light propagating through cartilage sample, over the visible spectral range (14000 - 28000 cm-1). It is shown that transmission and reflection spectra of human, pig and bovine cartilage are rather similar. It allows us to conclude that the pig cartilage can be used for in-vivo studies instead of human cartilage. The data obtained were treated by means of the one-dimensional diffusion approximation solution of the optical transport equation. We have found scattering coefficient s, absorption coefficient k and scattering anisotropy coefficient g by the iterative comparison of measured and calculated Tt, Rt and Ta values for human and pig cartilage. We found, in particular, that for 500 nm irradiation s equals 37,6 plus or minus 3.5 cm-1, g equals 0,56 plus or minus 0.05, k approximately equals 0,5 plus or minus 0.3 cm-1. The above data were used in Monte Carlo simulation for spatial intensity profile of light scattered by a cartilage sample. The computed profile was very similar to the profile measured using an Optical Multi-Channel Analyzer (OMA).

  9. Characterization of deposition from nasal spray devices using a computational fluid dynamics model of the human nasal passages.

    Science.gov (United States)

    Kimbell, Julia S; Segal, Rebecca A; Asgharian, Bahman; Wong, Brian A; Schroeter, Jeffry D; Southall, Jeremy P; Dickens, Colin J; Brace, Geoff; Miller, Frederick J

    2007-01-01

    Many studies suggest limited effectiveness of spray devices for nasal drug delivery due primarily to high deposition and clearance at the front of the nose. Here, nasal spray behavior was studied using experimental measurements and a computational fluid dynamics model of the human nasal passages constructed from magnetic resonance imaging scans of a healthy adult male. Eighteen commercially available nasal sprays were analyzed for spray characteristics using laser diffraction, high-speed video, and high-speed spark photography. Steadystate, inspiratory airflow (15 L/min) and particle transport were simulated under measured spray conditions. Simulated deposition efficiency and spray behavior were consistent with previous experimental studies, two of which used nasal replica molds based on this nasal geometry. Deposition fractions (numbers of deposited particles divided by the number released) of 20- and 50-microm particles exceeded 90% in the anterior part of the nose for most simulated conditions. Predicted particle penetration past the nasal valve improved when (1) the smaller of two particle sizes or the lower of two spray velocities was used, (2) the simulated nozzle was positioned 1.0 rather than 0.5 or 1.5 cm into the nostril, and (3) inspiratory airflow was present rather than absent. Simulations also predicted that delaying the appearance of normal inspiratory airflow more than 1 sec after the release of particles produced results equivalent to cases in which no inspiratory airflow was present. These predictions contribute to more effective design of drug delivery devices through a better understanding of the effects of nasal airflow and spray characteristics on particle transport in the nose.

  10. Substitution of R502 in existing refrigerating, air-conditioning and heat pump systems with refrigerants of low ozone depletion potential in the Federal Republic of Germany; Ersatz von R 502 in bestehenden Kaelte-, Klima- und Waermepumpenanlagen in der Bundesrepublik Deutschland durch Kaeltemittel mit geringerem Ozonabbaupotential

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1997-06-01

    The technical basics and the state of engineering for the substitution of R502 in existing refrigeration systems are described and explained. The report contains an overview of the current applications of R502 in the FRG, the presentation and discussion of existing substitutes, the presentation and valuations of research and experiences with the adaptation to alternative refrigerants, the presentation of the required infrastructure and a discussion of the technical feasibility. The conversion of existing systems to refrigerants of lower ozone depletion potential is in conclusion valuated with regard to its technical feasibility, environmental relevance and economic efficiency. (orig.) [Deutsch] Es werden die technischen Grundlagen und der Stand der Technik zum Ersatz von R502 in bestehenden Kaelteanlagen dargestellt und erlaeutert. Der Bericht beinhaltet einen Ueberblick ueber die derzeitige Anwendung von R502 in der BRD, die Vorstellung und Diskussion existierender Ersatzstoffe, die Darstellung und Bewertung der Forschung und Erfahrungen zu Umruestungen auf Ersatzstoffe, die Vorstellung der erforderlichen Infrastruktur und die Diskussion der technischen Durchfuehrbarkeit. Die Umstellung bestehender Anlagen auf Kaeltemittel mit geringerem Ozonabbaupotential wird abschliessend hinsichtlich der technischen Durchfuehrbarkeit, der Umweltrelevanz und der Wirtschaftlichkeit bewertet. (orig.)

  11. Von der Medienwirkungsbehauptung zur erziehungswissenschaftlichen Medienrezeptionsforschung. Vorschlag zur Analyse von Filmkommunikaten

    Directory of Open Access Journals (Sweden)

    Barbara Drinck

    2001-04-01

    Full Text Available Im Hinblick auf die Erforschung spezifischer Zusammenhänge von Medienkonsum und der Herausbildung von Einstellungen und Handlungen wird eine konstruktivistische Theorieorientierung plausibilisiert, indem zunächst auf den Stand der Medienwirkungsforschung eingegangen und vor dem Hintergrund einer begründeten Kritik des Wirkungsverständnisses auf die Notwendigkeit einer medienrezeptionswissenschaftlichen Forschungsalternative hingewiesen wird. Weiterhin wird der Stand der (erziehungswissenschaftlichen Medienrezeptionsforschung erörtert. Sodann werden Elemente einer konstruktivistischen Methodologie von Medienrezeptionsforschung beschrieben, die am Beispiel der Rezeption von Filmen konkretisiert werden. Dabei wird das Konzept des Kommunikates (S.J. Schmidt als Ausgangspunkt genommen, ein Vorschlag für eine Beschreibungssprache für (Film- Kommunikate entwickelt und eine Adaption des Ansatzes filmischer Narration zur Sprache gebracht.

  12. Erzeugung gleichverteilter Stichproben von Lozenge-Teilungen mittels Kopplung von Markovketten

    OpenAIRE

    Keller, Peter

    2011-01-01

    Aus dem Inhalt: 1 Einleitung 2 Eigenschaften der Lozengeteilungen 3 Coupling From The Past (CFTP) 4 Simulation von uniform verteilten Lozengeteilungen 5 Programmlisting und Diskussion der Implementierung 6 Ausblick A Anhang

  13. Der Briefwechsel zwischen Alexander von Humboldt und Karl Ernst von Baer

    Directory of Open Access Journals (Sweden)

    Thomas Schmuck

    2012-10-01

    Full Text Available Zusammenfassung Der kurze, nicht vollständig erhaltene Briefwechsel zwischen Alexander von Humboldt und Karl Ernst von Baer behandelt sehr verschiedene Themen: Politik, Kriegsgefahr, den Wissenschaftsbetrieb, Auszeichnungen und Tagungen, Embryologie und Cholera. Gemeinsam mit Briefen und Reden ergibt sich dabei ein differenziertes Bild der Beurteilung der beiden Wissenschaftler durch den jeweils anderen. Während Baer sich als Bewunderer Humboldts erweist, erscheint umgekehrt Humboldts Einschätzung Baers als ambivalent. Abstract The short, not completely preserved correspondence between Alexander von Humboldt and Karl Ernst von Baer deals with a wide range of subjects: politics and the danger of war, academic activities, scientific awards and conferences, aspects of embryology and the cholera. Letters to third persons and speeches, together with the correspondence between Humboldt and Baer show a differentiated pattern of mutual appraisal: While Baer always remained an admirer of the elder naturalist, Humboldt’s estimation was characterized by ambivalence.

  14. Effect of formulation- and administration-related variables on deposition pattern of nasal spray pumps evaluated using a nasal cast.

    Science.gov (United States)

    Kundoor, Vipra; Dalby, Richard N

    2011-08-01

    To systematically evaluate the effect of formulation- and administration-related variables on nasal spray deposition using a nasal cast. Deposition pattern was assessed by uniformly coating a transparent nose model with Sar-Gel®, which changes from white to purple on contact with water. Sprays were subsequently discharged into the cast, which was then digitally photographed. Images were quantified using Adobe® Photoshop. The effects of formulation viscosity (which influences droplet size), simulated administration techniques (head orientation, spray administration angle, spray nozzle insertion depth), spray pump design and metering volume on nasal deposition pattern were investigated. There was a significant decrease in the deposition area associated with sprays of increasing viscosity. This appeared to be mediated by an increase in droplet size and a narrowing of the spray plume. Administration techniques and nasal spray pump design also had a significant effect on the deposition pattern. This simple color-based method provides quantitative estimates of the effects that different formulation and administration variables may have on the nasal deposition area, and provides a rational basis on which manufacturers of nasal sprays can base their patient instructions or post approval changes when it is impractical to optimize these using a clinical study.

  15. Characterization of the nasal and oral microbiota of detection dogs.

    Directory of Open Access Journals (Sweden)

    Anitha Isaiah

    Full Text Available Little is known about physiological factors that affect the sense of olfaction in dogs. The objectives of this study were to describe the canine nasal and oral microbiota in detection dogs. We sought to determine the bacterial composition of the nasal and oral microbiota of a diverse population of detection canines. Nasal and oral swabs were collected from healthy dogs (n = 81 from four locations-Alabama, Georgia, California, and Texas. Nasal and oral swabs were also collected from a second cohort of detection canines belonging to three different detection job categories: explosive detection dogs (SP-E; n = 22, patrol and narcotics detection dogs (P-NDD; n = 15, and vapor wake dogs (VWD-E; n = 9. To understand if the nasal and oral microbiota of detection canines were variable, sample collection was repeated after 7 weeks in a subset of dogs. DNA was extracted from the swabs and used for 454-pyrosequencing of the16S rRNA genes. Nasal samples had a significantly lower diversity than oral samples (P<0.01. Actinobacteria and Proteobacteria were higher in nasal samples, while Bacteroidetes, Firmicutes, Fusobacteria, and Tenericutes were higher in oral samples. Bacterial diversity was not significantly different based on the detection job. No significant difference in beta diversity was observed in the nasal samples based on the detection job. In oral samples, however, ANOSIM suggested a significant difference in bacterial communities based on job category albeit with a small effect size (R = 0.1079, P = 0.02. Analysis of the composition of bacterial communities using LEfSe showed that within the nasal samples, Cardiobacterium and Riemerella were higher in VWD-E dogs, and Sphingobacterium was higher in the P-NDD group. In the oral samples Enterococcus and Capnocytophaga were higher in the P-NDD group. Gemella and Aggregatibacter were higher in S-PE, and Pigmentiphaga, Chryseobacterium, Parabacteroides amongst others were higher within the VWD-E group

  16. Characterization of the nasal and oral microbiota of detection dogs.

    Science.gov (United States)

    Isaiah, Anitha; Hoffmann, Aline Rodrigues; Kelley, Russ; Mundell, Paul; Steiner, Jörg M; Suchodolski, Jan S

    2017-01-01

    Little is known about physiological factors that affect the sense of olfaction in dogs. The objectives of this study were to describe the canine nasal and oral microbiota in detection dogs. We sought to determine the bacterial composition of the nasal and oral microbiota of a diverse population of detection canines. Nasal and oral swabs were collected from healthy dogs (n = 81) from four locations-Alabama, Georgia, California, and Texas. Nasal and oral swabs were also collected from a second cohort of detection canines belonging to three different detection job categories: explosive detection dogs (SP-E; n = 22), patrol and narcotics detection dogs (P-NDD; n = 15), and vapor wake dogs (VWD-E; n = 9). To understand if the nasal and oral microbiota of detection canines were variable, sample collection was repeated after 7 weeks in a subset of dogs. DNA was extracted from the swabs and used for 454-pyrosequencing of the16S rRNA genes. Nasal samples had a significantly lower diversity than oral samples (P<0.01). Actinobacteria and Proteobacteria were higher in nasal samples, while Bacteroidetes, Firmicutes, Fusobacteria, and Tenericutes were higher in oral samples. Bacterial diversity was not significantly different based on the detection job. No significant difference in beta diversity was observed in the nasal samples based on the detection job. In oral samples, however, ANOSIM suggested a significant difference in bacterial communities based on job category albeit with a small effect size (R = 0.1079, P = 0.02). Analysis of the composition of bacterial communities using LEfSe showed that within the nasal samples, Cardiobacterium and Riemerella were higher in VWD-E dogs, and Sphingobacterium was higher in the P-NDD group. In the oral samples Enterococcus and Capnocytophaga were higher in the P-NDD group. Gemella and Aggregatibacter were higher in S-PE, and Pigmentiphaga, Chryseobacterium, Parabacteroides amongst others were higher within the VWD-E group. Our initial

  17. Persistent organic compounds in food chains in Bavaria and Czechia. Pt. 1. Terrestrial systems; Persistente organische Verbindungen in Nahrungsketten von Bayern und Tschechien. T. 1. Terrestrische Systeme

    Energy Technology Data Exchange (ETDEWEB)

    Kettrup, A; Heinisch, E

    1997-10-01

    , zusammengetragen und - soweit dies moeglich war - verglichen und gegenuebergestellt. Die Ergebnisse sind in Zusammenfassungen der Einzelkapitel aufgefuehrt. Es konnte in z.T. fundierten Ansaetzen gezeigt werden, dass die unterschiedlichen sozialoekonomischen Strukturen der Regionen bis 1989 erhebliche Einfluesse auf die Ausmasse der Kontamination ausuebten. Umfangreiche Gesetzeswerke zur Anwendung und Herstellung von Chemieprodukten und deren immer dichtere Ueberwachung in Bayern fuehrten ebenso wie zahlreiche Sanierungsmassnahmen dazu, dass die klassischen chlororganischen Verbindungen nur noch in Spuren vorkommen und auch unvermeidbare Verbindungen wie PCDD/F minimiert werden koennen. Diese Voraussetzungen wurden in den neuen Bundeslaendern - hier dargestellt am Beispiel Brandenburg - wo bis 1989 die Volkswirtschaft ausschliesslich auf Produktionsmaximierungen ausgerichtet war, geschaffen und beginnen sich in deutlichen Abnahmen der Kontaminationshoehen (fuer PCDD/F und PAK lagen keine Materialien vor) insbesondere fuer die klassischen CKW auszuwirken. In Tschechien werden immer noch erheblich hoehere Belastungen z.B. fuer HCB und vor allem PCB registriert, die ein Augenmerk auf moegliche grenzueberschreitende Wirkungen erforderlich machen. (orig.)

  18. Untersuchungen zur Entwicklung von Satellitengalaxien

    Science.gov (United States)

    Seidel, Björn

    2002-01-01

    Gleichgewichtsmodelle ein- und zweikomponentiger Satellitengalaxien werden erzeugt und die Gezeiteneinwirkungen der als starres äußeres Potential angenommenen Milchstraße auf sie betrachtet. Eine erste Reihe von Simulationen mit anfänglich kugelsymmetrischen einkomponentigen Satelliten zeigt, daß sich nach elliptischer Deformation ein Balken und Schweife ungleicher Länge ausbilden, deren Aussehen sich periodisch ändert. Mithilfe von Vergleichssimulationen wurden folgende Phänomene am Satelliten entdeckt: (1) Hochdichtebereiche in den Schweifen, (2) Niedrigdichtebereiche um den Kern bzw. Balken und (3) ein oft verdeckter Balken. Analysiert wird das Erscheinungsbild in Zeitabhängigkeit. Die Teilchen gehen dem Kern über den Balken verloren und bewegen sich entlang gewisser stets gleich aussehender charakteristischer Strukturen in die Schweife. Nach einer Herleitung allgemeiner Größen des mehrkomponentigen Kingprofils werden drei stabile Standardmodelle zweikomponentiger Satellitengalaxien mit Massenverhältnis 1:10 (baryonische zu dunkle Materie) und unterschiedlicher Verteilung der dunklen und sichtbaren Materie gefunden. Ohne die Allgemeinheit der Ergebnisse zu beeinträchtigen, wurde dabei die Große Magellanische Wolke als Grundlage der Modelle genommen. Nach geeigneter Wahl der Bahn, zu der der Gezeitenradius des verwendeten dreikomponentigen Milchstraßenpotentials sowohl analytisch als auch numerisch berechnet wird, werden Simulationen der Modelle analysiert. Hauptaugenmerk ist das unterschiedliche Verhalten der Komponenten. Hauptergebnisse: (1) Es ist möglich, große Anteile dunkler, jedoch nur geringe sichtbarer Materie abzulösen. Dunkle und sichtbare Materie können unterschiedliche morphologische Strukturen bilden. (2) Je nach Konzentration der Komponenten ist die Eigengravitation der Teilchen mehr oder weniger für das Aussehen bestimmend. (3) Die Kernauflösung des Satelliten findet im Perigalaktikum (PG), sein Zerfall aber erst im

  19. A note on derivations of Murray–von Neumann algebras

    Science.gov (United States)

    Kadison, Richard V.; Liu, Zhe

    2014-01-01

    A Murray–von Neumann algebra is the algebra of operators affiliated with a finite von Neumann algebra. In this article, we first present a brief introduction to the theory of derivations of operator algebras from both the physical and mathematical points of view. We then describe our recent work on derivations of Murray–von Neumann algebras. We show that the “extended derivations” of a Murray–von Neumann algebra, those that map the associated finite von Neumann algebra into itself, are inner. In particular, we prove that the only derivation that maps a Murray–von Neumann algebra associated with a factor of type II1 into that factor is 0. Those results are extensions of Singer’s seminal result answering a question of Kaplansky, as applied to von Neumann algebras: The algebra may be noncommutative and may even contain unbounded elements. PMID:24469831

  20. A note on derivations of Murray-von Neumann algebras.

    Science.gov (United States)

    Kadison, Richard V; Liu, Zhe

    2014-02-11

    A Murray-von Neumann algebra is the algebra of operators affiliated with a finite von Neumann algebra. In this article, we first present a brief introduction to the theory of derivations of operator algebras from both the physical and mathematical points of view. We then describe our recent work on derivations of Murray-von Neumann algebras. We show that the "extended derivations" of a Murray-von Neumann algebra, those that map the associated finite von Neumann algebra into itself, are inner. In particular, we prove that the only derivation that maps a Murray-von Neumann algebra associated with a factor of type II1 into that factor is 0. Those results are extensions of Singer's seminal result answering a question of Kaplansky, as applied to von Neumann algebras: The algebra may be noncommutative and may even contain unbounded elements.

  1. Soolopartiid Von Krahli katuse all / Kristi Eberhart

    Index Scriptorium Estoniae

    Eberhart, Kristi

    2007-01-01

    Von Krahli Teatri kolmest lavastusest: "Erki ja Tiina" (lavastaja Mart Kangro, tantsivad Erki Laur ja Tiina Tauraite), "Faust" (J. W. Goethe ainetel tekst ja lavastus Taavi Eelmaa, muusika ja laulud Chalice, osades Jarek Kasar ja Rein Pakk), "Hamletid" (William Shakespeare'i ainetel kontseptsiooni, lavastuse, koreograafia, kujunduse, valguse autor Sasha Pepeljajev, video- ja helikunstnik Taavet Jansen. Esitaja Juhan Ulfsak)

  2. Alexander von Humboldt and Coenraad Jacob Temminck

    NARCIS (Netherlands)

    Raat, A.J.P.

    1976-01-01

    INTRODUCTION In the archives of the Rijksmuseum van Natuurlijke Historie in Leiden there is a map with three letters written by Alexander von Humboldt (17691859) to the first director of the Museum, Coenraad Jacob Temminck (1778-1858). The map, the hard cover of John Gould's "Synopsis of the birds

  3. Differential functional von Foerster equations with renewal

    Directory of Open Access Journals (Sweden)

    H.Leszczyński

    2008-06-01

    Full Text Available Natural iterative methods converge to the exact solution of a differential-functional von Foerster-type equation which describes a single population dependent on its past time and state densities as well as on its total size. On the lateral boundary we impose a renewal condition.

  4. Wege zur Entdeckung von Communities in Folksonomies

    OpenAIRE

    Jäschke, Robert; Hotho, Andreas; Schmitz, Christoph; Stumme, Gerd

    2006-01-01

    Ein wichtiger Baustein des neu entdeckten World Wide Web - des "Web 2.0" - stellen Folksonomies dar. In diesen Systemen können Benutzer gemeinsam Ressourcen verwalten und mit Schlagwörtern versehen. Die dadurch entstehenden begrifflichen Strukturen stellen ein interessantes Forschungsfeld dar. Dieser Artikel untersucht Ansätze und Wege zur Entdeckung und Strukturierung von Nutzergruppen ("Communities") in Folksonomies.

  5. Hans von Engel and the ICPIG Conference

    International Nuclear Information System (INIS)

    Franklin, R.

    2000-01-01

    The history of the, organized by Hans von Engel, International Conference on Phenomena in Ionized Gases is presented: Oxford (1953), Delft (1955), Venice (1957), Uppsala (1959), Munich (1961), Oxford (1971) and Berlin (1977). Some organizational aspects, financial support and remarkable events like international prizes in field of plasma physics are given

  6. Guido von Pirquet: Austrian pioneer of astronautics

    Science.gov (United States)

    Sykora, F.

    1977-01-01

    The works of Guido von Pirquet, Austrian pioneer of rocketry, were assessed. Major emphasis was given to Pirquet's calculation of the route to Venus which in fact was followed by the first Russian rocket to Venus. Of interest also is Pirquet's valuable construction of a space station and his analysis of interstellar space flight.

  7. Ueberreste vorweltlicher Proboscidier von Java und Banka

    NARCIS (Netherlands)

    Martin, K.

    1884-01-01

    Junghuhn führte in seinem Werke über Java nur einen einzigen Wirbelthierrest, Carcharias megalodon, an (7, IV, pag. 97); es war ihm nicht gelungen bei seinem ersten Aufenthalte auf der Insel Reste von Säugethieren zu finden, so eifrig er auch darnach in den Höhlen des Tertiaergebirges suchte (7, IV,

  8. Active Von Willebrand Factor, thrombocytopenia and thrombosis

    NARCIS (Netherlands)

    Hulstein, J.J.J.

    2006-01-01

    Platelets and von Willebrand factor (VWF) are unable to interact in circulation. To induce an interaction, a conversion of VWF to a platelet-binding conformation is required. At higher shear stresses, the first step in thrombus formation is binding of VWF to the subendothelium. This results in

  9. Ueber eine Anomalie von Acromitus flagellatus (Stiasny)

    NARCIS (Netherlands)

    Stiasny, G.

    1934-01-01

    Bei erneuter Durchsicht des reichhaltigen Materiales von Acromitus flagellatus (Stiasny) in der Scyphomedusen-Sammlung des Rijksmuseum van Natuurlijke Historie in Leiden (vergl. meine Mitteilungen daruber, 1920, Uebersichtstabelle III und 1921, p. 131/136) fand ich ein Exemplar, das eine

  10. Von Kalifornien nach Taxham / Katri Soe

    Index Scriptorium Estoniae

    Soe, Katri, 1971-

    2005-01-01

    Neljas osa magistritööst "Von Kalifornien nach Taxham: Formen und Strukturen der Kommunikation in Peter Handkes Romanen "Der kurze Brief zum langen Abschied" und "In einer dunklen Nacht ging ich aus meinem stillen Haus"" (Tartu, 2000. Juhendaja: Claus Sommerhage)

  11. Von der lernenden Region zur "Smart Region“

    OpenAIRE

    Poschwatta, Wolfgang

    2004-01-01

    Von der lernenden Region zur "Smart Region“ / M. Hilpert, W. Poschwatta. - In: Nabizadeh-Araghi, Nima : Auf dem Weg zur "Smart Region" : regionale Entwicklung am Beispiel der Pistazienproduktion im Iran. - Augsburg : Müllerdruck, 2004. - S. 5-9. - (Terra facta ; 2)

  12. An investigation into the usefulness of a rostrocaudal nasal radiographic view in the dog

    Directory of Open Access Journals (Sweden)

    R.M. Kirberger

    2002-07-01

    Full Text Available A rostrocaudal (RCd nasal view was developed in large breed mesaticephalic dogs using a complete, subsequently sectioned, skull and cadaver specimens to optimise the radiographic technique and evaluate normal anatomic features. Gelatin was placed in one nasal passage of the cadaver specimens to mimic the effects of nasal pathology. The latter specimens and 18 clinical cases with suspected nasal disease were evaluated to determine the usefulness of the RCd view compared to standard nasal views. An optimal RCd view was obtained with the dog in dorsal recumbency and the head symmetrically positioned with the hard palate perpendicular to the table using a table top technique with 8 : 1 grid, collimating to the nasal region and centring the primary beam on the philtrum. The dorsolateral aspects of the maxillary bone, the nasal bones, septal sulcus of the vomer, mucosa lined nasal septum and conchae could be seen. A centrodorsal more radiolucent area representing the ethmoid bone region was also visible. Gelatin soft tissue opacification of the nasal passage could be seen more clearly in RCd nasal view than in occlusal dorsoventral view. In clinical cases the RCd view was useful to build up a 3-dimensional image of nasal passage pathology as well as to detect nasal septum and osseous nasal border pathology not visible in other views. This view is particularly useful in cases where cross-sectional imaging modalities are not available or where the nasal investigation is limited by cost considerations.

  13. Nasal inflammation in sleep apnoea patients using CPAP and effect of heated humidification.

    Science.gov (United States)

    Koutsourelakis, I; Vagiakis, E; Perraki, E; Karatza, M; Magkou, C; Kopaka, M; Roussos, C; Zakynthinos, S

    2011-03-01

    Nasal continuous positive airway pressure (CPAP) can cause undesirable nasal symptoms, such as congestion to obstructive sleep apnoea (OSA) patients, whose symptoms can be attenuated by the addition of heated humidification. However, neither the nature of nasal symptoms nor the effect of heated humidification on nasal pathophysiology and pathology are convincingly known. 20 patients with OSA on nasal CPAP who exhibited symptomatic nasal obstruction were randomised to receive either 3 weeks of CPAP treatment with heated humidification or 3 weeks of CPAP treatment with sham-heated humidification, followed by 3 weeks of the opposite treatment, respectively. Nasal symptom score, nasal resistance, nasal lavage interleukin-6, interleukin-12 and tumour necrosis factor-α and nasal mucosa histopathology were assessed at baseline and after each treatment arm. Heated humidification in comparison with sham-heated humidification was associated with decrease in nasal symptomatology, resistance and lavage cytokines, and attenuation of inflammatory cell infiltration and fibrosis of the nasal mucosa. In conclusion, nasal obstruction of OSA patients on CPAP treatment is inflammatory in origin and the addition of heated humidification decreases nasal resistance and mucosal inflammation.

  14. Effect of solubility enhancement on nasal absorption of meloxicam.

    Science.gov (United States)

    Horváth, Tamás; Ambrus, Rita; Völgyi, Gergely; Budai-Szűcs, Mária; Márki, Árpád; Sipos, Péter; Bartos, Csilla; Seres, Adrienn B; Sztojkov-Ivanov, Anita; Takács-Novák, Krisztina; Csányi, Erzsébet; Gáspár, Róbert; Szabó-Révész, Piroska

    2016-12-01

    Besides the opioids the standard management of the World Health Organization suggests NSAIDs (non-steroidal anti-inflammatory drugs) alone or in combination to enhance analgesia in malignant and non-malignant pain therapy. The applicability of NSAIDs in a nasal formulation is a new approach in pharmaceutical technology. In order to enhance the nasal absorption of meloxicam (MX) as an NSAID, its salt form, meloxicam potassium monohydrate (MXP), registered by Egis Plc., was investigated in comparison with MX. The physico-chemical properties of the drugs (structural analysis, solubility and dissolution rate) and the mucoadhesivity of nasal formulations were controlled. In vitro and in vivo studies were carried out to determine the nasal applicability of MXP as a drug candidate in pain therapy. It can be concluded that MX and MXP demonstrated the same equilibrium solubility at the pH5.60 of the nasal mucosa (0.017mg/ml); nonetheless, MXP indicated faster dissolution and a higher permeability through the synthetic membrane. The animal studies justified the short T max value (15min) and the high AUC of MXP, which is important in acute pain therapy. It can be assumed that the low mucoadhesivity of MXP spray did not increase the residence time in the nasal cavity, and the elimination from the nasal mucosa was therefore faster than in the case of MX. Further experiments are necessary to prove the therapeutic relevance of this MXP-containing innovative intranasal formulation. Copyright © 2016 Elsevier B.V. All rights reserved.

  15. Automation of ultrasonic testing, instrumentation and rules for application and evaluation. Proceedings; Automatisierung der Ultraschallpruefung, Geraetetechnik und Regeln zur Anwendung und Auswertung. Vortraege des Seminars

    Energy Technology Data Exchange (ETDEWEB)

    Wuestenberg, H. [comp.

    1997-12-31

    The proceedings volume contains 18 lectures of the seminar addressing the following (selected) aspects: Requirements to be met by PC cards for US testing applications, defined by producers and appliers; digital technology and its impact on multichannel US testing instruments; the ALOK and array systems combined into one very efficient testing system (SAPHIR); a testing system combining US radiation source arrays and the pulsed eddy current method by means of highly integrated microelectronics (ASICs); regulatory standards and specifications for automated US testing; requirements for automated US testing in compliance with nuclear engineering codes; state of the art in standardisation for definition of required properties of US testing systems; critical review of the proposed standard relating to the TOFD method; automated evaluation shown with the example of US testing of pipelines. (orig./CB) [Deutsch] Dieser Band enthaelt 18 Vortraege mit folgenden Themen (Auswahl): Anforderungen an Ultraschall-PC-Karten aus der Sicht von Hersteller und Betreiber; Einfluss der Digitaltechnik auf Mehrkanal-Ultraschall-Pruefanlagen; Vereinigung der ALOK- und der Gruppenstrahler-Technik in einem leistungsfaehigen Pruefsystem (SAPHIR); Ein kombiniertes Pruefsystem fuer die Ultraschall-Gruppenstrahler- und Impuls-Wirbelstrom-Technik auf der Basis von hochintegrierter Mikroelektronik (ASICs); Regelwerke und Spezifikationen fuer die automatisierte Ultraschallpruefung; Anforderungen der kerntechnischen Regelwerke an die automatisierte Ultraschallpruefung; Stand der Normung bei der Charakterisierung der Eigenschaften von Ultraschall-Pruefsystemen; Kritische Bewertung des Normungsvorschlages zur Beugungslaufzeittechnik (TOFD); und Automatisierte Auswertung am Beispiel der Ultraschallpruefung von Fernrohrleitungen. (orig.)

  16. Effects of nasal corticosteroids on boosts of systemic allergen-specific IgE production induced by nasal allergen exposure.

    Directory of Open Access Journals (Sweden)

    Cornelia Egger

    Full Text Available Allergen exposure via the respiratory tract and in particular via the nasal mucosa boosts systemic allergen-specific IgE production. Intranasal corticosteroids (INCS represent a first line treatment of allergic rhinitis but their effects on this boost of allergen-specific IgE production are unclear.Here we aimed to determine in a double-blind, placebo-controlled study whether therapeutic doses of an INCS preparation, i.e., nasal fluticasone propionate, have effects on boosts of allergen-specific IgE following nasal allergen exposure.Subjects (n = 48 suffering from grass and birch pollen allergy were treated with daily fluticasone propionate or placebo nasal spray for four weeks. After two weeks of treatment, subjects underwent nasal provocation with either birch pollen allergen Bet v 1 or grass pollen allergen Phl p 5. Bet v 1 and Phl p 5-specific IgE, IgG1-4, IgM and IgA levels were measured in serum samples obtained at the time of provocation and one, two, four, six and eight weeks thereafter.Nasal allergen provocation induced a median increase to 141.1% of serum IgE levels to allergens used for provocation but not to control allergens 4 weeks after provocation. There were no significant differences regarding the boosts of allergen-specific IgE between INCS- and placebo-treated subjects.In conclusion, the application of fluticasone propionate had no significant effects on the boosts of systemic allergen-specific IgE production following nasal allergen exposure.http://clinicaltrials.gov/NCT00755066.

  17. Quasistatic field simulations based on finite elements and spectral methods applied to superconducting magnets; Quasistatische Feldsimulationen auf der Basis von Finiten Elementen und Spektralmethoden in der Anwendung auf supraleitende Magnete

    Energy Technology Data Exchange (ETDEWEB)

    Koch, Stephan

    2009-03-30

    This thesis is concerned with the numerical simulation of electromagnetic fields in the quasi-static approximation which is applicable in many practical cases. Main emphasis is put on higher-order finite element methods. Quasi-static applications can be found, e.g., in accelerator physics in terms of the design of magnets required for beam guidance, in power engineering as well as in high-voltage engineering. Especially during the first design and optimization phase of respective devices, numerical models offer a cheap alternative to the often costly assembly of prototypes. However, large differences in the magnitude of the material parameters and the geometric dimensions as well as in the time-scales of the electromagnetic phenomena involved lead to an unacceptably long simulation time or to an inadequately large memory requirement. Under certain circumstances, the simulation itself and, in turn, the desired design improvement becomes even impossible. In the context of this thesis, two strategies aiming at the extension of the range of application for numerical simulations based on the finite element method are pursued. The first strategy consists in parallelizing existing methods such that the computation can be distributed over several computers or cores of a processor. As a consequence, it becomes feasible to simulate a larger range of devices featuring more degrees of freedom in the numerical model than before. This is illustrated for the calculation of the electromagnetic fields, in particular of the eddy-current losses, inside a superconducting dipole magnet developed at the GSI Helmholtzzentrum fuer Schwerionenforschung as a part of the FAIR project. As the second strategy to improve the efficiency of numerical simulations, a hybrid discretization scheme exploiting certain geometrical symmetries is established. Using this method, a significant reduction of the numerical effort in terms of required degrees of freedom for a given accuracy is achieved. The problem-tailored discretization approach is based on a geometrical modeling of reduced spatial dimension inside respective domains of symmetry. For the approximation of the electromagnetic fields, orthogonal polynomials along the direction of symmetry are combined with finite element shape functions at the remaining cross-section. This leads to an efficient method providing a high accuracy. The domains of symmetry are embedded into the surrounding region by means of a strong coupling at the discrete level in terms of a domain decomposition approach. Using this strategy, for certain examples a level of accuracy corresponding to numerical models featuring several millions of degrees of freedom in classical finite element methods can be achieved with only one hundred thousand unknowns. This is demonstrated for different examples, e.g., a cylindrical power transformer and the already mentioned accelerator magnet. (orig.)

  18. Scaling up manufacturing of ZnO thin layers for application in flexible dye-sensitized solar cells; Aufskalierung der Herstellung von ZnO-Duennschichten fuer die Anwendung in flexiblen farbstoffsensibilisierten Solarzellen

    Energy Technology Data Exchange (ETDEWEB)

    Bittner, Florian

    2012-10-19

    Flexible solar cells possess good future prospects for versatile mobile applications and can provide an important environmental benefit. One of the technologies permitting flexible solar cells is that of dye-sensitized solar cells. Among other advantages the fabrication of these organic-inorganic hybrid solar cells promises to be inexpensive in comparison to other technologies. Nanoparticular TiO{sub 2} is used predominantly as the semiconducting photoanode material; however its preparation route contains a tempering step at about 450 C, which impedes the use of flexible plastic substrates - at least with the method established for dye-sensitized solar cells. An alternative to TiO{sub 2} is ZnO, which can be fabricated for example in an electrochemical process at temperatures of only 70 C in the form of porous quasicrystalline layers. To create porosity the dye eosin Y is used as structure-directing agent. In the context of this study layers prepared by this method were compared to ZnO layers prepared by screen printing. This was performed on glass based substrates. Better conversion efficiency has been determined for dye-sensitized solar cells based on electrochemical deposited layers, while other results indicated advantages for the screen printed layers. As the morphologies of the available screen printed layers proved to be unfavourable and poorly comparable, a concluding statement on the suitability of the different types of layers was eventually not possible. Furthermore a technical simple and inexpensive method for the platinum coating of plastic substrates, which are used as counter electrodes, was tried to be determined. However, layers prepared by technically relatively complex sputtering exhibited by far better properties than layers prepared by electrochemical deposition or by chemical reduction of platinum salts. Thus, the targeted objective has not been reached. The central scope of this study was the development of an electrochemical deposition setup to demonstrate the suitability for scale-up of the fabrication method of ZnO/eosin Y hybrid layers. This miniplant setup was characterised in detail and appropriate deposition parameters have been determined. Porous ZnO layers have been prepared successfully on FTO glass substrates on an area of 38.88 cm{sup 2} and on ITO-PET plastic substrates on an area of 34.56 cm{sup 2}. The suitability of the fabricated layers for the assembly of flexible dye-sensitized solar cells has been demonstrated by means of several operative modules. While these modules achieved decent conversion efficiencies of up to 2.58 % under low light intensities, strongly decreasing conversion efficiencies were observed with increasing light intensities. Too high series resistances have been identified as the cause. (orig.)

  19. Developing and applying a methodology for the scientific classification of publications on carbon capture and storage (CCS); Entwicklung und Anwendung einer Methodik zur wissenschaftlichen Einordnung von Publikationen zum Thema Carbon Capture and Storage (CCS)

    Energy Technology Data Exchange (ETDEWEB)

    Katz, Tobias; Sommer, Karl Christoph; Martens, Per Nicolai [RWTH Aachen (Germany). Inst. fuer Bergbaukunde I

    2012-05-15

    This article describes the conception and application of a methodology to scientifically classify publications on the Carbon Capture and Storage (CCS) topic. The first part of the presented methodology contains an analysis of both the fundamental positioning of the individual stakeholders writing about the CCS topic as well as their individual argumentative focus. For this purpose, all theses, which the individually analyzed stakeholders have included in their publications, are ascertained, classified, weighted, and evaluated. The second part of the methodology contains the linguistic evaluation (terminology) as well as the subsequent comparison of the individual stakeholders' linguistic and content related positions in a graphic depiction. The evaluations indicate that the theses associated with CCS technology in the reviewed publications primarily emphasize the economic and social aspects. The scope of the presented theses varies whereby only the publications of seven of the 28 reviewed stakeholders could be identified as being primarily ''holistically'' oriented. In addition, it can be seen that there is an above average number of stakeholders with a primarily negative position on the CCS topic in publications with a social argumentative focus. Another noticeable relationship exists between an economic argumentation and a positive position on the CCS topic. The linguistic analysis of the publications provides - as was to be expected - a clear correlation of the selected terminology and the argumentative focus. Stakeholders with a primarily negative argumentative focus tend to use therms with a negative connotation. The presented methodology can also be used in similar form in other controversially debated sectors. In principle, it is possible to also transfer this methodology to other topics outside the energy sector. It is, thus, possible to apply this method to any controversially debated topic for which a sufficiently large number of publications exists to help structurize the available literature and to identify the trends in the line of argumentation pursued by the various stakeholders. In addition, the results of the analyses of the diverse stakeholders can also be used as a comprehensive argumentative foundation for reviewing the respective topics as well as for critically examining one's own texts. (orig.)

  20. Non-Markovian dynamics, decoherence and entanglement in dissipative quantum systems with applications to quantum information theory of continuous variable systems; Nicht-Markovsche Dynamik, Dekohaerenz und Verschraenkung in dissipativen Quantensystemen mit Anwendung in der Quanteninformationstheorie von Systemen kontinuierlicher Variablen

    Energy Technology Data Exchange (ETDEWEB)

    Hoerhammer, C.

    2007-11-26

    In this thesis, non-Markovian dynamics, decoherence and entanglement in dissipative quantum systems are studied. In particular, applications to quantum information theory of continuous variable systems are considered. The non-Markovian dynamics are described by the Hu-Paz-Zhang master equation of quantum Brownian motion. In this context the focus is on non-Markovian effects on decoherence and separability time scales of various single- mode and two-mode continuous variable states. It is verified that moderate non-Markovian influences slow down the decay of interference fringes and quantum correlations, while strong non-Markovian effects resulting from an out-of-resonance bath can even accelerate the loss of coherence, compared to predictions of Markovian approximations. Qualitatively different scenarios including exponential, Gaussian or algebraic decay of the decoherence function are analyzed. It is shown that partial recurrence of coherence can occur in case of non-Lindblad-type dynamics. The time evolution of quantum correlations of entangled two-mode continuous variable states is examined in single-reservoir and two-reservoir models, representing noisy correlated or uncorrelated non-Markovian quantum channels. For this purpose the model of quantum Brownian motion is extended. Various separability criteria for Gaussian and non-Gaussian continuous variable systems are applied. In both types of reservoir models moderate non-Markovian effects prolong the separability time scales. However, in these models the properties of the stationary state may differ. In the two-reservoir model the initial entanglement is completely lost and both modes are finally uncorrelated. In a common reservoir both modes interact indirectly via the coupling to the same bath variables. Therefore, new quantum correlations may emerge between the two modes. Below a critical bath temperature entanglement is preserved even in the steady state. A separability criterion is derived, which depends on the bath temperature and the response function of the open quantum system. Thus, the extended quantum Brownian motion model of a two-mode continuous variable system in a common reservoir provides an example of quantum noise-induced entanglement. (orig.)

  1. Application of extracellular gadolinium-based MRI contrast agents and the risk of nephrogenic systemic fibrosis; Anwendung von extrazellulaeren gadoliniumhaltigen MR-Kontrastmitteln und Risiko der Nephrogenen Systemischen Fibrose

    Energy Technology Data Exchange (ETDEWEB)

    Heverhagen, J.T. [Univ. Hospital Bern (Switzerland). Inst. of Diagnostic, Interventional and Pediatric Radiology, Inselspital; Krombach, G.A. [Justus Liebig Univ. Hopsital Giessen (Germany). Diagnostic and Interventional Radiology; Gizewski, E. [Medical Univ. Innsbruck (Austria). Dept. of Neuroradiology

    2014-07-15

    Nephrogenic systemic fibrosis (NSF) is a serious, sometimes fatal disease. Findings in recent years have shown that a causal association between gadolinium containing contrast media and NSF is most likely. Therefore, the regulatory authorities have issued guidelines on the use of gadolinium-containing contrast media which have reduced the number of new cases of NSF to almost zero. However, it is for precisely this reason that the greatest care must still be taken to ensure that these guidelines are complied with. The most important factors are renal function, the quantity of gadolinium administered and coexisting diseases such as inflammation. All of these factors crucially influence the quantity of gadolinium released from the chelat in the body. This free gadolinium is thought to be the trigger for NSF. Other important factors are the stability of the gadolinium complex and furthermore the route of its elimination from the body. Partial elimination via the liver might be an additional protective mechanism. In conclusion, despite the NSF risk, contrast-enhanced MRI is a safe diagnostic procedure which can be used reliably and safely even in patients with severe renal failure, and does not necessarily have to be replaced by other methods.

  2. New findings on the application of in-lake technologies for neutralisation of acid mining lakes; Neue Erkenntnisse zur Anwendung von In-Lake-Verfahren fuer die Neutralisation saurer Bergbaufolgeseen

    Energy Technology Data Exchange (ETDEWEB)

    Rabe, W. [eta AG engineering, Spremberg (Germany); Uhlmann, W. [Institut fuer Wasser und Boden Dr. Uhlmann, Dresden (Germany)

    2006-07-01

    The neutralisation of acidic open cast mining lakes is an important task at the restoration of post lignit mining landscapes in Lusatia and Middle Germany. From several treatment technologies for the manipulation of ground and surface waters the in-lake-treatment procedures are most cost effective, licensable and usable with passable risks to reach ecological targets. The proceedings and the results of a two-stage-treatment technology of the Horstteich near Luckau will be exemplified in this article. In this case it was possible, within 20 days, to improve the water quality from extreme acidic (pH {approx} 2.8) to neutral conditions (pH > 8). During the neutralisation nearly all heavy metals and suspended substances were precipitated and a noticeable buffer was built up against acidic inflows. (orig.)

  3. Fabrication and examination of epitaxial HTSC/isolator thin films on sapphire substrates for application in high frequency devices; Herstellung und Untersuchung von epitaktischen HTSL/Isolator-Schichten auf Saphirsubstraten zur Anwendung in HF-Bauelementen

    Energy Technology Data Exchange (ETDEWEB)

    Kittel, H.

    1995-10-01

    The use of high temperature superconductors (HTSC) like YBCO with distinct lower surface resistance compared to normal conductors allows miniaturisation of high frequency (HF) circuits. The object of this work was the fabrication of YBCO thin films on low loss sapphire substrates applicable for stripline devices. To induce epitaxial growth and to avoid chemical reaction at the film-substrate boundary buffer layers were investigated. The examination of the growth properties and especially of the surface impedance has been allotted particular importance. In contrast to CaTiO{sub 3} it was possible to deposit CeO{sub 2}-buffer layers in direct growth up to a thickness of about 30 nm without cracks. The films show all growth properties required and even Laue-oscillations being a feature of high quality growth enabling the determination of film thickness distribution without destruction. The YBCO growth-, transport- and HF-properties meet the ones of YBCO films on standard substrates. A remarkable result is that the mosaic distribution of the CEO film, itself strongly dependend on film thickness, does not influence that of the YBCO film considerably. Rather it changes its shape subsequently due to YBCO deposition. A further particularity in contrast to deposition on standard substrates is the need to adjust the substrate heater tempeature for deposition of YBCO films with thicknesses {>=}300 nm needed for HF application. To demonstrate their usefullness some stripline devices like planar coils and side coupled filters have been fabricated and characterised. (orig.)

  4. Investigations of the oxidation-induced service life of chromium steels for high temperature fuel cell application (SOFC); Untersuchungen zur oxidationsbedingten Lebensdauer von Chromstaehlen fuer die Anwendung in der Hochtemperaturbrennstoffzelle (SOFC)

    Energy Technology Data Exchange (ETDEWEB)

    Ertl, S.T.

    2006-08-17

    The increasing energy consumption of future automobiles should be covered by a solid oxide fuel cell (SOFC) used as an additional energy supply (auxiliary power unit). The application of a SOFC with about 5 kW power in cars requires small size, low weight and an economic fabrication. To achieve this goal the interconnector and the metallic anode substrate (depending on an alternative concept of construction) should be manufactured out of thin Crofer22APU, a high chromium ferritic steel. The scale formation mechanisms on Crofer22APU sheets, wires and powder metallurgical produced foils of different thicknesses were investigated in several atmospheres of water vapour/hydrogen at 800 and 900 C, simulating the anode conditions. For scale characterization a number of conventional analysis techniques such as optical metallography, scanning electron microscopy and X-ray diffraction were used in combination with deflection testing in monofacial oxidation and two-stage oxidation studies using {sup 18}O and H{sub 2} {sup 18}O tracer. With these results a theoretical model for the determination of lifetime was developed for Crofer22APU components in simulated anode gas. It was found that the lifetime at a given temperature depends not only on the surface-to-volume ratio, but also on the geometry of the component (e.g. sheet or wire). The critical Cr content required for breakaway oxidation depends on microcrack formation in the surface oxide scale, which occurs on ridges of a sheet during thermal cycling. The development of a metallic interconnector and a metallic anode substrate requires measures to avoid interdiffusion between the alloy and the bordering nickel-YSZ (yttrium stabilized zirconia) cermet of the anode, or depending on the conception of the stack, the bordering nickel-YSZ cermet of the anode functional layer. Therefore the suitability of preoxidation layers after different preoxidation conditions was tested. It was found that the inhibition of the interdiffusion depends not only on the preoxidation conditions, but also on the conditions under which the nickel layer was applied. (orig.)

  5. Quality-oriented production of brown-coal coke with due regard to its application in metallurgy and environmental protection; Qualitaetsgerechte Erzeugung von Braunkohlenkoks unter Beruecksichtigung der Anwendung in Metallurgie und Umweltschutz

    Energy Technology Data Exchange (ETDEWEB)

    Achtelik, M.; Erken, M.; Juessen, P.; Knapp, A. [Rheinbraun AG, Koeln (Germany)

    1998-12-31

    In the nineteen seventies the Fortuna Nord refining factory of Rheinbraun AG began to restructure its operations from domestic coal briquetting to the manufacture of industrial products. One of these products, high-temperature brown-coal coke, is produced in two hearth-type furnaces. Coke produced in these plants is mainly used in metallurgy and environmental engineering, in the latter especially for flue gas purification. Rheinbraun has succeeded in introducing a quality management system for brown-coal coke which ensures high quality and security of supply. (orig.) [Deutsch] Im Veredlungsbetrieb Fabrik Fortuna-Nord der Rheinbraun AG begann in den 70er Jahren der Strukturwandel vom Hausbrandbrikett zu Industrieprodukten. Eins dieser Produkte, der Hochtemperatur-Braunkohlenkoks, wird in zwei Herdofenanlagen erzeugt. Die Haupteinsatzbereiche des Herdofenkokses sind die Metallurgie sowie der Umweltschutz und hier insbesondere die Rauchgasreinigung. Um die hohe Produktqualitaet und die Liefersicherheit zu gewaehrleisten, hat Rheinbraun ein Qualitaetsmanagementsystem fuer Braunkohlenkoks erfolgreich eingefuehrt. (orig.)

  6. Practical application of the microbial activity analysis on the monitoring of the process biological stability of biogas plants; Praktische Anwendung der mikrobiellen Aktivitaetsanalyse zur Ueberwachung der prozessbiologischen Stabilitaet von Biogasanlagen

    Energy Technology Data Exchange (ETDEWEB)

    Neumann, Lukas; Tietjen, Carsten [MT-Energie GmbH, Zeven (Germany). Forschung und Entwicklung; Rilling, Norbert [MT-Energie GmbH und Co. KG, Rockstedt (Germany)

    2013-10-01

    As extension for the classical fluorescence microscopic analysis of the microbial population in a biogas fermenter the cell counts and frequency of the different methanogenic organisms was used to generate the plant specific stability indicator called MT-Factor. This factor describes the optimal composition of the microbial population for the current process conditions and could be used for the biological process consulting. A study of the MT-Energie laboratory showed that the combination of the microbial cell counts determination and the plant specific stability factor shifts during a process instability or failure of a biogas fermenter. This analysis of the methane-forming microorganisms as well as their cell count and importance for the entire anaerobic biology of the biogas plant can be used for clearly visualizing and tracking the vitality of the digestion process. The evaluation of the microbial activity of different liquid manure samples could show the influence of inhibitors like disinfectant or cleaning agents directly without time consuming cultivation tests. By determining the MT-Factor and analyzing the activity of the methane formers, an impending influence of inhibitors can be detected in liquid manure before the manure enters the digester. This way, a negative influence on the gas yield can be avoided. (orig.)

  7. New certification process starts. Pt. 2. Application of Building Information Modeling (BIM) for the certification according to DGNB; Zertifizierungsprozess auf ''neuen Beinen''. T. 2. Anwendung von Building Informationen (BIM) zur Zertifizierung nach DGNB

    Energy Technology Data Exchange (ETDEWEB)

    Essig, Bernd [SCHOLZE Consulting GmbH, Leinfelden-Echterdingen (Germany). Geschaeftsbereich Ingenieur-Beratungsleistungen in Facility-, Informations-, Qualitaets-, Nachhaltigkeitsmanagement und Energieberatung; Ernst, Tatjana [SCHOLZE Consulting GmbH, Leinfelden-Echterdingen (Germany)

    2013-04-01

    The overall life cycle plays a significant role in the certification by German Sustainable Building Council (Stuttgart, Federal Republic of Germany). In order that certification becomes much more than only a documentation, comprehensive data are requested already in an early phase of planning. Early investigations of alternatives may have a significant influence on the life cycle of a building. But, from where do the auditors achieve these amounts of data without overcharging the partners involved in the planning process with questions. The Building Information Modelling contributes to the development of the future enhancement of process quality by an innovative information management.

  8. Organic semiconductors. Fundamental aspects of metal contacts, highly ordered films and the application in field effect transistors; Organische Halbleiter. Fundamentale Aspekte von Metallkontakten, hochgeordneten Schichten und deren Anwendung in Feldeffekttransistoren

    Energy Technology Data Exchange (ETDEWEB)

    Sachs, Soenke

    2010-05-31

    In this thesis, fundamental aspects of organic semiconductor devices are investigated and incorporated into the construction and optimization of an organic semiconductor field effect transistor (OFET). In order to approach the ''high end'' of OFETs, elaborate steps to optimize the devices are taken, despite the fact that they might not be feasible in a direct application. Well-characterized model systems are selected to study fundamental properties of devices, in particular the electronic structure at molecule/metal contacts and in the organic semiconductor bulk, as well as the growth of organic semiconductor molecules on single crystalline insulator substrates. The realization of a high performance OFET is pursued by a comprehensive approach in order to optimize particularly the interfaces of the device. Considerable progress is made towards a working OFET with best possible properties. A primary focus of this work, the investigation of the electronic structure at molecule/metal contacts and in the molecular bulk of the model system PTCDA/Ag(111) is performed using two photon photoelectron spectroscopy (2PPE). Of special interest is the excitation of the lowest unoccupied molecular orbital (LUMO) that shows different energetic relaxation mechanisms, depending on the origin of excitation. In addition to the importance of the molecule/metal contacts, the performance of OFETs is determined to a large extend by the quality of the organic semiconductor/gate insulator interface where the charge carrier channel is established. The morphology and structure of a molecular layer are investigated for diindenoperylene (DIP) molecules, adsorbed on a single crystalline Al{sub 2}O{sub 3} substrate, by atomic force microscopy and optical microscopy. Dependent on the substrate temperature during growth, the morphology shows grains with lateral dimensions of about 200 nm at 350 K which increase up to 700 nm at 450 K. This change in morphology is accompanied by an increase of roughness, indicating a change of the growth mode, at higher temperatures. At slightly higher temperatures of about 460 K, the growth of crystallites is observed. Depending on the particular preparation parameters, three different types of crystallites develop: mesa crystallites with lateral dimensions up to several microns, dendritic crystallites, characterized by kinetic growth processes, and layered crystallites, that are bent in three dimensions. Possibilities to utilize the grown crystallites in OFETs are discussed and the mesa type is found to be the most promising. The comprehensive concept for the development of a high performance OFET is introduced and refined in details. Improvements are made especially in the construction of the gate electrode that will be attached beneath the Al{sub 2}O{sub 3} substrate. To thin out the substrate, a drilling technique is improved and combined with wet chemical etching, resulting in gate insulator thicknesses below 10 {mu}m. On the basis of this preparatory work few first OFETs were built. As a first step towards the electrical characterization of DIP-OFETs, OFETs based on Silicon-oxide were successfully prepared and characterized. Moreover, present challenges and possible improvements towards a high performance OFET are discussed. (orig.)

  9. Temperature dependent electronic structure and magnetism of metallic systems with localized moments. Application on gadolinium; Temperaturabhaengige elektronische Struktur und Magnetismus von metallischen Systemen mit lokalisierten Momenten. Anwendung auf Gadolinium

    Energy Technology Data Exchange (ETDEWEB)

    Santos, C.A.M. dos

    2005-06-24

    This thesis focuses on the theoretical investigation of the temperature dependent electronic and magnetic properties of metallic 4f-systems with localized magnetic moments. The presented theory is based on the Kondo-lattice model, which describes the interaction between a system of 4f-localized magnetic moments and the itinerant conduction band electrons. This interaction is responsible for a remarkable temperature dependence of the electronic structure mainly induced by the subsystem of 4f-localized moments. The many-body problem provoked by the Kondo-lattice model is solved by using a moment conserving Green function technique, which takes care of several special limiting cases. This method reproduces the T=0-exact solvable limiting case of the ferromagnetically saturated semiconductor. The temperature dependent magnetic properties of the 4f-localized subsystem are evaluated by means of a modified Rudermann-Kittel-Kasuya-Yosida (RKKY) type procedure, which together with the solution of the electronic part allows for a self-consistent calculation of all the electronic and magnetic properties of the model. Results of model calculations allow to deduce the conditions for ferromagnetism in dependence of the electron density n, exchange coupling J and temperature T. The self-consistently calculated Curie temperature T{sub C} is presented and discussed in dependence of relevant parameters (J, n, and W) of the model. The second part of the thesis is concerned with the investigation of the temperature dependence of the electronic and magnetic properties of the rare-earth metal Gadolinium (Gd). The original Kondo-lattice model is extended to a multi-band Kondo-lattice model and combined with an ab-initio band structure calculation to take into account for the multi-bands in real systems. The single-particle energies of the model are taken from an augmented spherical wave (ASW) band structure calculation. The proposed method avoids the double counting of relevant interactions by exploiting the T=0-exact limiting case of the ferromagnetically saturated semiconductor and takes into account the correct symmetry of the atomic orbitals. The only parameter of the theory (inter-band exchange coupling J) is uniquely fixed by the band structure calculation. The self-consistently derived Curie temperature of 294.1 K and the T=0-magnetic moment of 7.71 {mu}{sub B} are surprisingly close to the experimental values. The induced temperature-dependence of the 5d conduction bands explains respective experimental photoemission data. (orig.)

  10. Application and further development of models for the final repository safety analyses on the clearance of radioactive materials for disposal. Final report; Anwendung und Weiterentwicklung von Modellen fuer Endlagersicherheitsanalysen auf die Freigabe radioaktiver Stoffe zur Deponierung. Abschlussbericht

    Energy Technology Data Exchange (ETDEWEB)

    Artmann, Andreas; Larue, Juergen; Seher, Holger; Weiss, Dietmar

    2014-08-15

    The project of application and further development of models for the final repository safety analyses on the clearance of radioactive materials for disposal is aimed to study the long-term safety using repository-specific simulation programs with respect to radiation exposure for different scenarios. It was supposed to investigate whether the 10 micro Sv criterion can be guaranteed under consideration of human intrusion scenarios. The report covers the following issues: selection and identification of models and codes and the definition of boundary conditions; applicability of conventional repository models for long-term safety analyses; modeling results for the pollutant release and transport and calculation of radiation exposure; determination of the radiation exposure.

  11. Further development of the radioimmunoassay for carcinoembryonic antigen and the use of the measurement of the carcinoembryonic antigen in stools. Weiterentwicklung des Radioimmunoassay fuer carcino-embryonales Antigen und Anwendung auf die Messung von carcino-embryonalem Antigen im Stuhl

    Energy Technology Data Exchange (ETDEWEB)

    Britsch, R F

    1982-01-01

    A specific, direct CEA-RTA is presented with sequential saturation and double antibody separation and using guinea pig CEA anti-serums, whose isolated CEA was marked with /sup 125/I for tracer production and used as was for a CEA standard. This RIA was tested on serum from patients with colorectal and stomach-esophagus carcinomas and from healthy persons, whereby it showed a good sensitivity in comparison to control serums on the market. CEA is also present in a high concentration in the stools, however very nonhomogeneously distributed, by patients as well as healthy persons. An increased stool CEA value does not necessarily indicate a carcinomatic disease or even a preliminary stage. During a screening a carcinomatic intestinal disorder should not be looked for intensively unless there are first several positive stool CEA values or additional positive blood evidence in the stool. Simultaneously carried out determinations of serum and stool CEA allows for the discovery of more patients as the use of only one. (TRV)

  12. Contribution to the grain refinement of hypoeutectic aluminium-silicon casting alloys: application of a new grain refiner and experience from practice; Beitrag zur Kornfeinung von untereutektischen Aluminium-Silicium-Gusslegierungen: Anwendung eines neuen Kornfeiners und Erfahrungen aus der Praxis

    Energy Technology Data Exchange (ETDEWEB)

    Koch, H. [Aluminium Rheinfelden GmbH, Rheinfelden (Germany)

    2000-10-01

    This paper describes the application of a master alloy on the basis of aluminium-titanium-boron, that is designed for hypoeutectic aluminium-silicon casting alloys. The efficiency of the grain refiner was measured using thermal analysis and sand and permanent mould casted samples. The grain size was measured using metallographic technique. In addition, casting trials using a spiral sand mould were carried out to estimate the influence on the flowing behaviour of the melt. To compare the results, a standard AlTi5B1 rod was used under the same test conditions. Finally, results from practice are shown. The grain refinement mechanism is discussed. (orig.)

  13. Development of an advanced dispersion model for regulatory purposes; Ueberpruefung der Grundlagen der Ausbreitungsrechnung der TA Luft im Hinblick auf eine EG-Harmonisierung: Entwicklung eines fortschrittlichen Ausbreitungsmodells zur Anwendung im Rahmen von Genehmigungsverfahren

    Energy Technology Data Exchange (ETDEWEB)

    Scherer, B.; Reimer, E. [Freie Univ. Berlin (Germany). Inst. fuer Meteorologie; Yamartino, R.J. [Earth Tech., Inc., Concord, MA (United States); Klug, W. [Technische Hochschule Darmstadt (Germany). Inst. fuer Meteorologie

    1998-12-01

    A new Lagrangian Particle Model and a meteorological suite to operate the model were developed during phase 1 of the project. The model-system was applied for a long term calculation. The new Kinematic Simulation Particle Dispersion Model (KSP) uses Kinematic Simulation and Monte-Carlo (KS-MC) theory to calculate sub-grid flowfields. It calculates snapshots of concentrations rater then ensemble mean values. It can also directly provide higher moments of concentrations, C{sup (n)}(t) and is applicable for odour problems as well. The model is applicable in a wide spatial (<10-10{sup 3} km) and temporal scale (sec. to years). The meteorological model TRAMPER includes a date archive 3d Objective Analysis with statistical O/I method and a 1-d boundary-layer model as well as prognostic non-hydrostatic model (GESIMA). The analysis provides a three dimensional and time dependent description of relevant meteorological scalar and vector quantities also trajectories in a approx. 30 km grid resolution. Higher resolution is gained by GESIMA (example). As an alternative driver the CALMET Meteorological Model is presented. The evaluation of the KSP will take place in phase 2. Only preliminary results are shown in the report. (orig.) [German] In Phase 1 des Vorhabens wurde ein neues Lagrange - Partikel - Modell (LPM) mit einer meteorologischen Simulationsumgebung (Treiber) entwickelt und fuer eine immissionsklimatologische Berechnung eingesetzt. Das 'Kinematic Simulation Particle' - Ausbreitungsmodell (KSP) arbeitet mit einem subskaligen Stroemungsprozessor nach der 'Kinematic Simulation - Monte Carlo-Methode. Es berechnet Momentanwerte und nicht Ensemblemittelwerte sowie Varianzen und hoehere zeitliche Momente der Konzentration C{sup (n)}(t) und ist fuer die Geruchsausbreitungsrechnung geeignet. Das Verfahren erfasst einen weiten raeumlichen (<10-10{sup 3} km) und zeitlichen Skalenbereich (Sek. bis Jahre). Das meteorologische Modellsystem TRAMPER als Treiber umfasst Datenarchiv, dreidimensionale Objektive Analyse mit statischer Interpolation, 1-d-Grenzschichtmodell und nichthydrostatisches Modell (GESIMA). Erzeugt werden u.a. 3-d-Stroemung, Mischungsschichthoehe und mikrophysikalische Variablen in einem Gitter mit ca. 30 km Aufloesung. Hoehere Aufloesung wird mit GESIMA erzielt (Beispiel) Als alternativer Treiber wird das meteorologische Modell CALMET vorgestellt. Die Evaluierung des KSP ist in der Phase 2 des Vorhabens vorgesehen. Vorlaeufige Ergebnisse koennen in diesem Bericht gezeigt werden. (orig.)

  14. A method for load management in low voltage grids. Application from e-mobility to heat storage; Verfahren zum Lastmanagement in Niederspannungsnetzen. Anwendung von E-Mobility bis Waermespeicher

    Energy Technology Data Exchange (ETDEWEB)

    Hess, Tobias; Schegner, Peter [TU Dresden (Germany). IEEH; Hable, Matthias [ENSO NETZ GmbH, Dresden (Germany)

    2012-07-01

    With the expected charging characteristic of e-mobility a considerable load peak during the night is expected. The paper describes the application of a modified maximal rectangle algorithm to determine the optimal starting times for charging to realise a flat load curve. The load characteristic of e-mobility is similar to heat storage. This allows to use the currently widely spread heat storage devices as example for developing and testing methods for optimized load management in low voltage networks. It is shown that the developed optimization algorithm finds solutions close to the global optimum even in large networks ({approx} 25000 devices) with low requirements of calculation time (< 1 min). (orig.)

  15. A model for the description of the coolant mixing and its application to the analysis of boron dilution transients in pressurized water reactors; Ein Modell zur Beschreibung der Kuehlmittelvermischung und seine Anwendung auf die Analyse von Borverduennungstransienten in Druckwasserreaktoren

    Energy Technology Data Exchange (ETDEWEB)

    Kliem, Soeren

    2010-08-15

    A model for the realistic description of the coolant mixing inside the pressure vessel of a pressurized water reactors has been developed and validated. This fast running model is based on the linear superposition of response functions on Dirac-pulse-like perturbations of the coolant parameters. It has been implemented into the coupled code system DYN3D/ATHLET nad serves as the interface between the one-dimensional thermal hydraulic system code ATHLETE and the 3D neutron kinetic core model DYN3D. By help of this model, the coolant mixing inside the reactor pressure vessel can e simulated in an efficient manner. A methodology for this analysis of hypothetical boron dilution accidents has been developed, which is based on the newly developed model for the coolant mixing. This methodology consists of a combination of stationary and transient calculations including a realistic treatment of the mixing of deborated slugs on the way towards the reactor core. The degree of conservatism can be adjusted by the variation of the initial size of the deborated slug. This new method was applied to two different boron dilution accidents. Besides the start of the first main coolant pump with a deborated slug of coolant in the cold leg of the primary circuit, a deboration event during the operation of the residual heat removal system was investigated. The results of the parameter study for a reactor core with a generic loading pattern demonstrated in both cases, that although the shut-down reactor becomes re-critical safety relevant cladding temperature limits are not reached, even if maximum possible volumes of the deborated slug are considered. The main reason for these results is the use of realistic time-dependent distributions of the boron concentration at the inlet of each fuel assembly.

  16. Rare occupational cause of nasal septum perforation: Nickel exposure.

    Science.gov (United States)

    Bolek, Ertugrul Cagri; Erden, Abdulsamet; Kulekci, Cagri; Kalyoncu, Umut; Karadag, Omer

    2017-10-06

    Many etiologies are held accountable for nasal septum perforations. Topical nasal drug usage, previous surgeries, trauma, nose picking, squamous cell carcinoma, some rheumatological disorders such as granulomatosis with polyangiitis (Wegener granulomatosis), some infectious diseases such as syphilis and leprosy are among the causes of the perforations. Occupational heavy metal exposures by inhalation rarely may also cause nasal septum perforation. Here, we present a 29-year-old patient without any known diseases, who is a worker at a metallic coating and nickel-plating factory, referred for investigation of his nasal cartilage septum perforation from an otorhinolaryngology clinic. The patient questioning, physical examination and laboratory assessment about rheumatic and infectious diseases were negative. There was a metallic smell in the breath during the physical examination. The analysis showed serum nickel level at 31 μg/l and urine nickel at 18 μg/l (84.11 μg/g creatinine). Other possible serum and urine heavy metal levels were within normal ranges. Nickel exposure is usually together with other heavy metals (chromium or cadmium), it is rarely alone. Nickel ingested by inhalation usually leads to respiratory problems such as reduced olfactory acuity, ulcers, septum perforation or tumors of the nasal sinuses. This case demonstrates the importance of occupational anamnesis and awareness of diagnosis. Int J Occup Med Environ Health 2017;30(6):963-967. This work is available in Open Access model and licensed under a CC BY-NC 3.0 PL license.

  17. Reconstruction of Nasal Skin Cancer Defects with Local Flaps

    Directory of Open Access Journals (Sweden)

    A. C. Salgarelli

    2011-01-01

    Full Text Available Reconstruction of nasal defects must preserve the integrity of complex facial functions and expressions, as well as facial symmetry and a pleasing aesthetic outcome. The reconstructive modality of choice will depend largely on the location, size, and depth of the surgical defect. Individualized therapy is the best course, and numerous flaps have been designed to provide coverage of a variety of nasal-specific defects. We describe our experience in the aesthetic reconstruction of nasal skin defects following oncological surgery. The use of different local flaps for nasal skin cancer defects is reported in 286 patients. Complications in this series were one partial flap dehiscence that healed by secondary intention, two forehead flaps, and one bilobed flap with minimal rim necrosis that resulted in an irregular scar requiring revision. Aesthetic results were deemed satisfactory by all patients and the operating surgeons. The color and texture matches were aesthetically good, and the nasal contour was distinct in all patients. All scars were inconspicuous and symmetrical. No patient had tenting or a flat nose.

  18. Does gently clearing the nasal passage affect odor identification?

    Directory of Open Access Journals (Sweden)

    Mitchell G. Spring

    2014-12-01

    Full Text Available Identifying scents in a wine’s bouquet is considered one of the most important steps in the process of wine tasting. An individual’s ability to successfully do this is dependent on the sense of smell; thus, altering the nasal microenvironment could have a powerful effect on the wine tasting experience. In the present study, we examined olfactory performance in healthy participants who cleared their nasal cavity before odorant presentations. Fifty undergraduate participants were assessed with a standardized test of olfaction requiring the recognition of a battery of odors. Half of these participants cleared mucus from their nasal cavities (by gently blowing their noses prior to the assessment. No difference was found in performance between those who cleared their nasal passages and those who did not. Further, data were not different than known population data from the test. These data suggest that gently clearing the nasal cavity before presentation of odorants bears no effect on the ability to perceive those odor qualities.

  19. Use of aesthetic rhinoplasty procedures in reconstructive nasal surgery.

    Science.gov (United States)

    Ghassemi, Alireza; Rübben, Albert; Bohluli, Behnam; Hölzle, Frank; Ghassemi, Mehrangiz

    2015-01-01

    Resection of cancer often involves the excision of underlying hard tissue, and some procedures in aesthetic rhinoplasty can be used in reconstructive nasal surgery to increase the margin of safety while still achieving an acceptable aesthetic and functional outcome. We have used techniques from aesthetic rhinoplasty to shape the nasal framework. Osteotomy and formation of the tip were used in 17 patients with defects (ranging from 1 to 3.5 cm in size) from the nasal root to the tip of the nose. After the underlying bony or cartilaginous framework, or both, had been removed, the resulting open roof deformity had to be corrected by osteotomy of the bony nasal wall and the tip shaped by excision and suturing, including insertion of the tip graft and columellar strut graft. After this, and narrowing of the nose, the defect was smaller and could be closed with local tissue without tension. There were no deformities in the contour, and patency of the airway was maintained. Patients were satisfied with both the aesthetic and functional results. Although the margin of safety was increased, shaping the nasal framework reduced the size of the defect, which allowed tension-free closure with a local flap. The operation requires a thorough knowledge of procedures used in aesthetic rhinoplasty. Copyright © 2014 The British Association of Oral and Maxillofacial Surgeons. Published by Elsevier Ltd. All rights reserved.

  20. Isotonic saline nasal irrigation in clinical practice: a literature review

    Directory of Open Access Journals (Sweden)

    Sabrina Costa Lima

    Full Text Available Abstract Introduction: Nasal instillation of saline solution has been used as part of the treatment of patients with upper respiratory tract diseases. Despite its use for a number of years, factors such as the amount of saline solution to be used, degree of salinity, method and frequency of application have yet to be fully explained. Objective: Review the reported outcomes of saline nasal irrigation in adults with allergic rhinitis, acute or chronic sinusitis and after functional endoscopic sinus surgery (FESS, and provide evidence to assist physiotherapists in decision making in clinical practice. Methods: A search was conducted of the Pubmed and Cochrane Library databases between 2007 and 2014. A combination of the following descriptors was used as a search strategy: nasal irrigation, nasal lavage, rhinitis, sinusitis, saline, saline solution. Results: Eight clinical trials were included, analyzed according to participant diagnosis. Conclusion: The evidence found was heterogeneous, but contributed to elucidating uncertainties regarding the use of nasal lavage in the clinical practice of physical therapy, such as the protocols used.

  1. Risk of contamination of nasal sprays in otolaryngologic practice

    Directory of Open Access Journals (Sweden)

    Akkuzu Babur

    2007-03-01

    Full Text Available Abstract Background Reusable nasal-spray devices are frequently used in otolaryngologic examinations, and there is an increasing concern about the risk of cross-contamination from these devices. The aim of our study was to determine, by means of microbiologic analysis, the safety of a positive-displacement or pump-type atomizer after multiple uses. Methods A reusable nasal spray bottle, pump, and tips were used in the nasal physical examination of 282 patients admitted to a tertiary otolaryngology clinic. The effectiveness of 2 different methods of prophylaxis against microbiologic contamination (the use of protective punched caps or rinsing the bottle tip with alcohol was compared with that of a control procedure. Results Although there was no statistically significant difference in positive culture rates among the types of nasal spray bottles tested, methicillin-resistant coagulase-negative staphylococci were isolated in 4 of 198 cultures. Conclusion Given these findings, we concluded that additional precautions (such as the use of an autoclave between sprays, disposable tips, or disposable devices are warranted to avoid interpatient cross-contamination from a reusable nasal spray device.

  2. Gradual approach to refinement of the nasal tip: surgical results

    Directory of Open Access Journals (Sweden)

    Thiago Bittencourt Ottoni de Carvalho

    2015-02-01

    Full Text Available Introduction: The complexity of the nasal tip structures and the impact of surgical maneuvers make the prediction of the final outcome very difficult. Therefore, no single technique is enough to correct the several anatomical presentations, and adequate preoperative planning represents the basis of rhinoplasty. Objective: To present results of rhinoplasty, through the gradual surgical approach to nasal tip definition based on anatomical features, and to evaluate the degree of patient satisfaction after the surgical procedure. Methods: Longitudinal retrospective cohort study of the medical charts of 533 patients of both genders who underwent rhinoplasty from January of 2005 to January of 2012 was performed. Cases were allocated into seven groups: (1 no surgery on nasal tip; (2 interdomal breakup; (3 cephalic trim; (4 domal suture; (5 shield-shaped graft; (6 vertical dome division; (7 replacement of lower lateral cartilages. Results: Group 4 was the most prevalent. The satisfaction rate was 96% and revision surgery occurred in 4% of cases. Conclusion: The protocol used allowed the implementation of a gradual surgical approach to nasal tip definition with the nasal anatomical characteristics, high rate of patient satisfaction with the surgical outcome, and low rate of revision.

  3. Extranasopharyngeal angiofibroma of nasal septum. A controversial entity

    Science.gov (United States)

    Tasca, I; Ceroni Compadretti, G

    2008-01-01

    Summary The term extranasopharyngeal angiofibroma has been applied to vascular, fibrous nodules occurring outside the nasopharynx. The maxillary sinus is the most common site involved, while the nasal septum represents an extremely rare localization. Computerized tomography scan and magnetic resonance imaging are used to determine the tumour site and its extension. Surgical excision of the mass is the treatment of choice, and recurrence is rare. Typically, clinical characteristics of extranasopharyngeal angiofibromas do not conform with that of nasopharyngeal angiofibromas and, for this reason, these tumours must be regarded as a separate entity. Due to these different features, extranasopharyngeal angiofibromas can present a diagnostic challenge and a meticulous evaluation with a high index of suspicion is essential in establishing the correct diagnosis and treatment. We report the case of a 57-year-old female with a 1-year history of a slowly progressing right nasal obstruction due to the presence of a whitish mass adhering to the posterior nasal septum. The patient was succesfully treated surgically. Histopathological findings were compatible with a diagnosis of angiofibroma. Extranasopharyngeal angiofibroma must be taken into consideration in the differential diagnosis of nasal vascular tumours and nasal septum should be regarded as a potential, though exceptional, localization of these neoplasms. PMID:19205598

  4. Nasal myiasis: report of a case and literature review

    Directory of Open Access Journals (Sweden)

    Reyes-Romero, Karen Eliana

    2016-07-01

    Full Text Available Myiasis is the infection of animal or human tissues or organs by larvae of Diptera. It may affect individuals of any age, but is more common in middle-aged and elderly patients. Nasal myiasis, an infection of the nasal and paranasal cavities by such larvae, is a common disease in tropical and developing countries. Reported cases of nasal myiasis have been caused by several different species, such as Lucilia sericata in Korea and Iran, Estro ovis in Algeria and France, Lucilia cuprina and Phaenicia sericata in Malaysia, Cochliomyia hominivorax in French Guiana, Drosophila melanogaster in Turkey, Eristalis tenax in Iran and Oestrus ovis in Israel. Signs and symptoms are related to the presence and movement of the larvae, and include foreign body sensation, bloody or muco-purulent nasal discharge. Prevention may be done with insect repellent. Treatment is based on antiparasitic drugs and techniques for removal of larvae, but may include the use of prophylactic topical or systemic antibiotics for possible secondary infections. We report a case of nasal and left maxillary sinus myiasis in an elderly woman, who responded favorably to treatment.

  5. Rare occupational cause of nasal septum perforation: Nickel exposure

    Directory of Open Access Journals (Sweden)

    Ertugrul Cagri Bolek

    2017-10-01

    Full Text Available Many etiologies are held accountable for nasal septum perforations. Topical nasal drug usage, previous surgeries, trauma, nose picking, squamous cell carcinoma, some rheumatological disorders such as granulomatosis with polyangiitis (Wegener granulomatosis, some infectious diseases such as syphilis and leprosy are among the causes of the perforations. Occupational heavy metal exposures by inhalation rarely may also cause nasal septum perforation. Here, we present a 29-year-old patient without any known diseases, who is a worker at a metallic coating and nickel-plating factory, referred for investigation of his nasal cartilage septum perforation from an otorhinolaryngology clinic. The patient questioning, physical examination and laboratory assessment about rheumatic and infectious diseases were negative. There was a metallic smell in the breath during the physical examination. The analysis showed serum nickel level at 31 μg/l and urine nickel at 18 μg/l (84.11 μg/g creatinine. Other possible serum and urine heavy metal levels were within normal ranges. Nickel exposure is usually together with other heavy metals (chromium or cadmium, it is rarely alone. Nickel ingested by inhalation usually leads to respiratory problems such as reduced olfactory acuity, ulcers, septum perforation or tumors of the nasal sinuses. This case demonstrates the importance of occupational anamnesis and awareness of diagnosis. Int J Occup Med Environ Health 2017;30(6:963–967

  6. Effects of radiation on nasal mucosa of guinea pig

    International Nuclear Information System (INIS)

    Xiao Mang; Hu Sunhong; Liu Yuehui

    2004-01-01

    Objective: To study histopathological changes in nasal mucosa of guinea pigs following a series of irradiation. Methods: A total of 60 healthy guinea pigs were divided into two groups randomly: the irradiation group (n=30) and the control group (n=30). The animals of the irradiation group were exposed nasally to linear accelerator X-rays at 5.0 Gy once a week for three weeks. At 1 d, 1 w, 2 w, 4 w, 10 w and half year after X-irradiation five animals per one group were sacrificed randomly, at each time point. Their middle nasal turbinate mucosa was observed under optical microscope and electron microscope, and were analysed by image analysis for histopathological transformation. Results: In the irradiation group, the early histopathological transformation was acute inflammatory reaction, at the fourth week the mucosa began to repair, which ended at the sixth month. But after repaired, some parts of the repaired mucosa were lined with squamous epithelium instead of the normal nasal mucosa. The rate of the cilia-covered area was only 52.9% at the sixth month. Conclusion: The nasal mucosa injury and the squamous metaplasia could form a pathological basis of dysfunction after irradiation

  7. Reconstruction of Nasal Skin Cancer Defects with Local Flaps

    International Nuclear Information System (INIS)

    Salgarelli, A. C.; Bellini, P.; Multinu, A.; Consolo, U.; Magnoni, C.; Francomano, M.; Fantini, F.; Seidenari, S.

    2011-01-01

    Reconstruction of nasal defects must preserve the integrity of complex facial functions and expressions, as well as facial symmetry and a pleasing aesthetic outcome. The reconstructive modality of choice will depend largely on the location, size, and depth of the surgical defect. Individualized therapy is the best course, and numerous flaps have been designed to provide coverage of a variety of nasal-specific defects. We describe our experience in the aesthetic reconstruction of nasal skin defects following oncological surgery. The use of different local flaps for nasal skin cancer defects is reported in 286 patients. Complications in this series were one partial flap dehiscence that healed by secondary intention, two forehead flaps, and one bilobed flap with minimal rim necrosis that resulted in an irregular scar requiring revision. Aesthetic results were deemed satisfactory by all patients and the operating surgeons. The color and texture matches were aesthetically good, and the nasal contour was distinct in all patients. All scars were inconspicuous and symmetrical. No patient had tenting or a flat nose.

  8. Aspergilosis nasal en un perro: reporte de un caso

    Directory of Open Access Journals (Sweden)

    Camilo Padilla Peñuela

    2014-07-01

    Full Text Available La aspergilosis nasal es una de las principales causas de afección crónica de las fosas nasales en el canino. La sinología clínica es típica en toda enfermedad nasal crónica. Se presenta sobre todo epistaxis y ocasionalmente dolor. La evaluación rinoscópica de la zona permite encontrar hallazgos asociados con la patología y tomar muestras para citología y cultivo. La terapéutica sistémica con antifúngicos orales ha sido de utilidad variable, pero actualmente se ha remplazado con la medicación tópica directa en el área afectada. Este artículo describe el caso clínico de un canino, macho de cuatro años de edad, que fue presentado a consulta por secreción nasal mucosanguinolenta unilateral con una semana de evolución. El paciente se venía tratando en otro centro veterinario con ciclonamina y vitamina K por un posible trastorno en la coagulación. Después de una serie de exámenes que incluyeron rinoscopia y cultivo para hongos, se diagnosticó aspergilosis nasal. Se realizaron dos aplicaciones de clotrimazol intranasal que permitieron la resolución de los signos clínicos.

  9. Nasal changes after orthognathic surgery for patients with prognathism and Class III malocclusion: Analysis using three-dimensional photogrammetry

    Directory of Open Access Journals (Sweden)

    Saran Worasakwutiphong

    2015-02-01

    Conclusion: After the surgery, characteristic nasal changes occurred with an increase of nasolabial angle and nostril show, but a preserved nasal width. The majority of patients did not perceive adverse nasal changes.

  10. Humidification of inspired oxygen is increased with pre-nasal cannula, compared to intranasal cannula.

    Science.gov (United States)

    Dellweg, Dominic; Wenze, Markus; Hoehn, Ekkehard; Bourgund, Olaf; Haidl, Peter

    2013-08-01

    Oxygen therapy is usually combined with a humidification device, to prevent mucosal dryness. Depending on the cannula design, oxygen can be administered pre- or intra-nasally (administration of oxygen in front of the nasal ostia vs cannula system inside the nasal vestibulum). The impact of cannula design on intra-nasal humidity, however, has not been investigated to date. First, to develop a system, that samples air from the nasal cavity and analyzes the humidity of these samples. Second, to investigate nasal humidity during pre-nasal and intra-nasal oxygen application, with and without humidification. We first developed and validated a sampling and analysis system to measure humidity from air samples. By means of this system we measured inspiratory air samples from 12 subjects who received nasal oxygen with an intra-nasal and pre-nasal cannula at different flows, with and without humidification. The sampling and analysis system showed good correlation to a standard hygrometer within the tested humidity range (r = 0.99, P humidification (P = .001, P humidification. With the addition of humidification we observed no significant change in humidity at any flow, and independent of pre- or intranasal oxygen administration. Pre-nasal administration of dry oxygen achieves levels of intranasal humidity similar to those achieved by intranasal administration in combination with a bubble through humidifier. Pre-nasal oxygen simplifies application and may reduce therapy cost.

  11. Utilidad del colgajo frontal en la reconstrucción nasal Usefulness of the forehead flap in the nasal reconstruction

    Directory of Open Access Journals (Sweden)

    Julio César Gálvez Chávez

    2009-03-01

    Full Text Available INTRODUCCIÓN. La nariz constituye el centro estético de la cara y cualquier deformidad en ella afecta de modo importante a la armonía facial. Este estudio tuvo como objetivo caracterizar las experiencias en reconstrucción nasal con colgajo frontal en pacientes con defectos anatómicos de la nariz, como consecuencia fundamentalmente de una cirugía oncológica. MÉTODOS. Se realizó un estudio descriptivo, prospectivo, para caracterizar la experiencia de la reconstrucción nasal con colgajo frontal en pacientes con defectos nasales, atendidos en el Hospital «Hermanos Ameijeiras» y en el Instituto Nacional de Oncología y Radiobiología, entre junio de 1999 y mayo de 2007. RESULTADOS. Destacó que el motivo más frecuente de reconstrucción fue la lesión neoplásica, con igual número de pacientes afectados por carcinoma basocelular y epidermoide. El ala nasal fue la zona más afectada y se presentó recidiva tumoral en 5 pacientes. En todos los casos se pudo crear una cubierta externa al defecto y el diseño oblicuo fue el más utilizado. Se reconstruyó la cubierta interna nasal fundamentalmente con injerto de piel total y el soporte nasal, mayormente con injertos cartilaginosos de la concha auricular. Todos los colgajos frontales se mantuvieron vitales después de su desconexión en el segundo tiempo quirúrgico. El cierre directo de la zona donante fue el más utilizado y en algunos casos se logró con la utilización de expansión tisular. Se realizó un tercer tiempo de remodelación en los pacientes que lo necesitaron. Las complicaciones no afectaron al resultado final de la reconstrucción. CONCLUSIONES. Se demostró la utilidad y vigencia del colgajo frontal en la reconstrucción nasal.ABSTRACT INTRODUCTION. The nose is the aesthetic center of the face and any deformity in it significantly affects facial harmony. This study was aimed at characterizing the experiences in nasal reconstruction with forehead flap in patients with

  12. REVIEW OF NASAL CHANGES WITH MAXILLARY ORTHOGNATHIC SURGERY

    Directory of Open Access Journals (Sweden)

    Leila KHAMASHTA-LEDEZMA

    2017-02-01

    Full Text Available This article reviews the literature on nasal changes with maxillary orthognathic surgery. Understanding such changes is vital for surgical planning and for obtaining appropriate informed consent, and there are medico-legal implications. During orthognathic surgical planning a prediction of the effects of the different surgical movements is possible and this forms part of the basis of the planning stage. The predicted changes need to be identified and their desirability or not for each individual patient determined. Some techniques for managing undesirable nasal changes are discussed, including adjunct measures to minimize these potential effects (e.g. cinch sutures, and additional surgical procedures to manage the undesired nasal changes once they are produced.

  13. Nasal Filters For Relief From Atopic Dermatitis Caused by Inhalants

    Directory of Open Access Journals (Sweden)

    J S Pasricha

    1989-01-01

    Full Text Available Nasal filter is a simple device consisting of a net mounted in a frame made to fit inside the nostrils. These filters thus are not visible from outside. If a person uses the nasal filters the .u particulate material from the air that the person breathes gets removed and in case the person is allergic to an inhalant antigen, he stops having the allergic symptoms. We tried nasal filters on two females patients aged 32 and 7 years respectively, having topics dermatitis the age of I year, caused by an inhalant (indicated by seasonal aggravations, and spontaneous recovery during brief visits to other towns. Unrig a follow-up of 2 1/2 and 2 years respectively, both the patients experienced almost 80-90% relief from the dermatitis and required only animal treatment.

  14. Histamine and tryptase in nasal lavage fluid after allergen challenge

    DEFF Research Database (Denmark)

    Jacobi, H H; Skov, P S; Poulsen, L K

    1999-01-01

    BACKGROUND: Antihistamines (H1-receptor antagonists) act by competitive antagonism of histamine at H1-receptors. In addition, high concentrations of some antihistamines inhibit allergen-induced histamine release from mast cells in vitro. OBJECTIVE: The purpose of this study was to determine...... the effect of intranasal azelastine or systemic cetirizine (both potent antihistamines) on the allergen-induced release of mast-cell mediators from the human nasal mucosa in vivo. METHODS: Patients allergic to birch pollen (n = 11) and control subjects not allergic to birch pollen (n = 5) were included......, nasal allergen challenges were performed, and the number of sneezes were counted. In addition, nasal lavage fluid was collected, and the levels of mast-cell mediators (histamine and tryptase) were measured. RESULTS: The allergen challenge of patients allergic to pollen produced sneezing...

  15. Comparison of nasal Midazolam with Ketamine versus nasal Midazolam as a premedication in children

    Directory of Open Access Journals (Sweden)

    Sonal S Khatavkar

    2014-01-01

    Full Text Available Background: T his study was done to compare effects of intranasal midazolam and intranasal midazolam with ketamine for premedication of children aged 1-12 yrs undergoing intermediate and major surgeries. Aims: Midazolam and Ketamine have already been used as premedicants in children. Our aim was to find out advantage of combination of midazolam with ketamine over midazolam by nasal route. Methods: Sixty children of age group 1-12 yrs of American Society of Anesthesiologists (ASA grade 1 and 2 were selected. Group A- midazolam (0.2 mg/kg, Group B- midazolam (0.15 mg/kg + ketamine 1 mg/kg. Both groups received drug intranasally 30 min before surgery in recovery room with monitored anesthesia care. Onset of sedation, sedation score, emotional reaction, intravenous cannula acceptance, and mask acceptance were studied. Statistical Analysis: Unpaired t test and chi square test. Results: Sedation score, anxiolysis, attitude, reaction to intravenous cannulation, face mask acceptance, and emotional reaction were significantly better in midazolam with ketamine group. Intra operatively, in both groups, pulse rate, oxygen saturation, and respiratory rate had no significant difference; also, post operatively, no significant difference was observed in above parameters, post operative analgesia was significantly better in midazolam with ketamine group. Conclusions: Intra nasal premedication allows rapid and predictable sedation in children. Midazolam as well as combination of Midazolam with ketamine gives good level of sedation and comfort. But quality of sedation, analgesia, and comfort is significantly better in midazolam with ketamine group. No significant side effects were observed in both groups.

  16. MRT of the knee joint of juvenile footballers. Are there early changes in the knee due to competitive sport?; MRT der Kniegelenke jugendlicher Fussballspieler. Gibt es Fruehveraenderungen von Kniebinnenstrukturen durch Leistungssport?

    Energy Technology Data Exchange (ETDEWEB)

    Wacker, F. [Abt. fuer Radiologische Diagnostik und Nuklearmedizin, Klinikum Steglitz, Freie Univ. Berlin (Germany); Koenig, H. [Abt. fuer Radiologische Diagnostik und Nuklearmedizin, Klinikum Steglitz, Freie Univ. Berlin (Germany); Felsenberg, D. [Abt. fuer Radiologische Diagnostik und Nuklearmedizin, Klinikum Steglitz, Freie Univ. Berlin (Germany); Wolf, K.J. [Abt. fuer Radiologische Diagnostik und Nuklearmedizin, Klinikum Steglitz, Freie Univ. Berlin (Germany)

    1994-02-01

    In a prospective study, the right knee of 21 symptom free juvenile footballers was examined by MRT (group I) and the results were compared with 12 juveniles of similar age but who did not take part in any special sorting activities (group II). A 1.5 Tesla Magnetome with an extremity coil was used. There were no abnormal changes in either group in the cruciate ligaments. The hyaline cartilage medially was about 10% thicker than laterally in both groups but in group I it was, on average, 24.8% thicker than in group II. Increased signals in the centre of the menisci were observed in 8 members of group I and two in group II. 5 on the 8 in group I, but none in group II, also showed an increase in the joint fluid. (orig.) [Deutsch] In einer retrospektiven Studie wurde das rechte Kniegelenk von 21 beschwerdefreien, jungendlichen Fussballspielern (Gruppe I) sowie von 12 altersgleichen Jungendlichen ohne spezielle sportliche Aktivitaeten (Gruppe II) magnetresonanztomographisch untersucht. Die Messungen erfolgten an einem 1,5-Tesla-Magnetom unter Anwendung einer Extremitaetenspule. Keine pathologischen Veraenderungen ergaben sich bei beiden Gruppen im Bereich der Kreuzbaender. Der hyaline Gelenkknorpel zeigte bei beiden Gruppen am medialen Femurkondylus eine um etwa 10% hoehere Dicke als lateral und erweis sich bei Gruppe I im Mittel um 24,8% dicker als bei Gruppe II. Zentrale Meniskus-Signalvermehrungen konnten bei 8 Jugendlichen der Gruppe I sowie bei zwei der Gruppe II nachgewiesen werden. Dabei wiesen 5/8 der Gruppe I, aber keiner der Gruppe II begleitend eine Gelenkfluessigkeitsvermehrung auf. (orig.)

  17. Thermodynamic aspects of heavy metal volatility during utilisation of the energetic and material fraction of waste materials; Schwermetallfluechtigkeit bei der energetischen und stofflichen Verwertung von Abfaellen aus der Sicht der Thermodynamik

    Energy Technology Data Exchange (ETDEWEB)

    Meyer, B; Starke, A [TU Bergakademie Freiberg (Germany). Inst. IEC

    1998-09-01

    Co-combustion plants, in which fuel is partly substituted by waste materials, are subject to the 17th BImSchV (Nuisance Control Ordinance) provided that the thermal fraction of 25% is not exceeded. Emission limits are calculated proportionately on the basis of limiting values for emissions from coal power stations (13th BImSchV) and waste incinerators (17th BImSchV). Compared to coal, waste has higher concentrations of heavy metals and halogens, which results in enhanced emissions of heavy metal compounds and chlorides with the flue gas and gasification gas. Plant operators intending to opt for co-combustion must check if the existing flue gas purification system is efficient enough to meet the specifications of the 17th BImSchV. In general, thermodynamic modelling is the most common method of evaluation and optimisation for high-temperature processes of this kind. (orig./SR) [Deutsch] Da bei der Mitverbrennung ein Teil des Brennstoffes durch den Reststoff substituiert wird, unterliegen diese Anlagen der Anteilsregelung nach 17. BImSchV, sofern ein thermischer Anteil von 25% nicht ueberschritten wird. Emissionsgrenzwerte werden anteilig aus den z.B. fuer Kohlekraftwerke gueltigen Grenzwerten nach TA Luft oder 13. BImSchV und denen fuer Abfaelle u.ae. nach 17 BImSchV ermittelt. Der hier betrachtete Reststoff Muell beinhaltet im Vergleich zur Kohle hohe Konzentrationen an Schwermetallen und Halogenen. Dies laesst eine erhoehte Emission von Schwermetallverbindungen und Chloriden mit dem Rauchgas bzw. Vergasungsgas erwarten. Es muss in jedem Fall ueberprueft werden, ob die vorhandene Rauchgasreinigung ausreicht, wenn bei der Mitverbrennung/-vergasung die Emissionsgrenzwerte der 17. BImSchV zur Anwendung kommen. Als Bewertungs- und Optimierungsmethode fuer derartige Hochtemperaturprozesse setzt sich die thermodynamische Modellierung zunehmend durch. (orig./SR)

  18. High-efficiency absorption-type heat pumps and refrigerators. From topology to the pilot plant; Hocheffiziente Absorptionsmaschinen zur Versorgung mit Kaelte und Waerme. Von der Topologie zur Pilotanlage

    Energy Technology Data Exchange (ETDEWEB)

    Ziegler, F.; Demmel, S.; Lamp, P. [Bayerisches Zentrum fuer Angewandte Energieforschung e.V. (ZAE Bayern), Wuerzburg (Germany); Kahn, R. [Technische Univ. Muenchen (Germany). Physik Dept. E19; Alefeld, G.

    1998-12-31

    Absorption-type heat pumps or refrigerators are systems operated with heat. They have been known for a long time and are frequently used especially in airconditioning in the USA and south-east Asia. However, the conventional technique used is subject to many physical limitations, restricting their broader use. The paper demonstrates ways of overcoming these restrictions, for instance by multi-stage design. The exploitation of topological principles much facilitates the synthesis of novel circuits. The technical relevance of such developments is demonstrated by means of selected examples of executed laboratory and pilot plants. Modern absorption technology saves resources and prevents environmental pollution by consuming less fossil energy compared with the conventional technique, for instance by harnessing the thermal potential of solar energy or utilizing waste heat and residual heat, and, not least, thanks to the use of natural refrigerants. (orig.) [Deutsch] Absorptionswaermepumpen oder -kaeltemaschinen sind durch Waerme angetriebene Anlagen, die seit langem bekannt sind und besonders in der Klimatechnik in den USA und im suedostasiatischen Raum haeufig eingesetzt werden. Die dabei verwendete konventionelle Technik unterliegt allerdings vielfaeltigen physikalischen Einschraenkungen, die ihre noch breitere Anwendung verhindern. Es wird gezeigt, wie diese Einschraenkungen beispielsweise durch Mehrstufigkeit ueberwunden werden koennen. Durch die Verwendung topologischer Grundsaetze wird die Synthese neuartiger Kreislaeufe stark vereinfacht. Die technische Bedeutung solcher Entwicklungen wird an ausgewaehlten Beispielen ausgefuehrter Labor- und Pilotanlagen gezeigt. Durch den im Vergleich zu konventioneller Technik geringeren Verbrauch an fossiler Energie, beispielsweise durch die thermische Nutzung von Sonnenenergie oder durch die Nutzung von Ab- oder Restwaerme und nicht zuletzt durch die Verwendung natuerlicher Kaeltemittel werden bei Einsatz moderner

  19. Detecting Nasal Vowels in Speech Interfaces Based on Surface Electromyography.

    Directory of Open Access Journals (Sweden)

    João Freitas

    Full Text Available Nasality is a very important characteristic of several languages, European Portuguese being one of them. This paper addresses the challenge of nasality detection in surface electromyography (EMG based speech interfaces. We explore the existence of useful information about the velum movement and also assess if muscles deeper down in the face and neck region can be measured using surface electrodes, and the best electrode location to do so. The procedure we adopted uses Real-Time Magnetic Resonance Imaging (RT-MRI, collected from a set of speakers, providing a method to interpret EMG data. By ensuring compatible data recording conditions, and proper time alignment between the EMG and the RT-MRI data, we are able to accurately estimate the time when the velum moves and the type of movement when a nasal vowel occurs. The combination of these two sources revealed interesting and distinct characteristics in the EMG signal when a nasal vowel is uttered, which motivated a classification experiment. Overall results of this experiment provide evidence that it is possible to detect velum movement using sensors positioned below the ear, between mastoid process and the mandible, in the upper neck region. In a frame-based classification scenario, error rates as low as 32.5% for all speakers and 23.4% for the best speaker have been achieved, for nasal vowel detection. This outcome stands as an encouraging result, fostering the grounds for deeper exploration of the proposed approach as a promising route to the development of an EMG-based speech interface for languages with strong nasal characteristics.

  20. Alar setback technique: a controlled method of nasal tip deprojection.

    Science.gov (United States)

    Foda, H M

    2001-11-01

    To describe an alar cartilage-modifying technique aimed at decreasing nasal tip projection in cases with overdeveloped alar cartilages and to compare it with other deprojection techniques used to correct such deformity. Selected case series. University and private practice settings in Alexandria, Egypt. Twenty patients presenting for rhinoplasty who had overprojected nasal tips primarily due to overdeveloped alar cartilages. All cases were primary cases except for one patient, who had undergone 2 previous rhinoplasties. An external rhinoplasty approach was used to set back the alar cartilages by shortening their medial and lateral crura. The choice of performing a high or low setback depended on the preexisting lobule-to-columella ratio. Following the setback, the alar cartilages were reconstructed in a fashion that increased the strength and stability of the tip complex. Subjective evaluation included clinical examination, analysis of preoperative and postoperative photographs, and patient satisfaction. Objective evaluation of nasal tip projection, using the Goode ratio and the nasofacial angle, was performed preoperatively and repeated at least 6 months postoperatively. A low setback was performed in 16 cases (80%) and a high setback in 4 (20%). The mean follow-up period was 18 months (range, 6-36 months). The technique effectively deprojected the nasal tip as evidenced by the considerable postoperative decrease in values of the Goode ratio and the nasofacial angle. No complications were encountered and no revision surgical procedures were required. The alar setback technique has many advantages; it results in precise predictable amounts of deprojection, controls the degree of tip rotation, preserves the natural contour of the nasal tip, respects the tip support mechanisms, increases the strength and stability of nasal tip complex, preserves or restores the normal lobule-to-columella proportion, and does not lead to alar flaring. However, the technique requires

  1. A study of nasal cavity volume by magnetic resonance imaging

    Energy Technology Data Exchange (ETDEWEB)

    Tosa, Yasuyoshi [Showa Univ., Tokyo (Japan). School of Medicine

    1992-04-01

    The nasal cavity volume in 69 healthy volunteers from 8 to 23 years old (17 males and 52 females) was studied using magnetic resonance imaging (MRI). Merits of MRI such as no radiation exposure, less artifact due to bone and air and measurement of intravascular blood flow; and demerits such as contraindication in users of heart pace-makers or magnetic clips, contraindication in people with claustrophobia and influence of environmental magnetic fields must be considered. A Magunetom M10 (Siemens), a superconduction device with 1.0 Tesla magnetic flux density was used. Enhanced patterns of T[sub 1], and pulse lines were photographed at 600 msec TR (repetition time) and 19 msec TE (echo time) using SE (spin echo) and short SE (spin echo), and 3 or 4 mm slices. Photographs were made of the piriform aperture, choana, superior-middle-inferior concha including the nasal meatus, the frontal sinus, maxillary sinus, cribriform plate, and upper surface of the palate. The line connecting the maximum depression point in the nasal root and the pontomedullary junction was selected by sagittal median section, because this corresponds well with the CM (canthomeatal) line which is useful in CT (computed tomography). The transverse section of the nasal cavity volume was traced by display console with an accessory MRI device and calculated by integration of the slice width. The increase of height and body weight neared a plateau at almost 16 years, whereas increase of nasal cavity volume continued until about 20 years. Pearson's coefficient of correlation and regression line were significant. There were no significant differences in these parameters between male and female groups. Comparatively strong correlation between nasal cavity volume, and age, height and body weight was statistically evident. (author).

  2. The use of a camera-enabled mobile phone to triage patients with nasal bone injuries.

    LENUS (Irish Health Repository)

    Barghouthi, Taleb

    2012-03-01

    To identify the accuracy of a camera-enabled mobile phone in assessing patients with nasal bone injuries and to determine if treatment in the form of manipulation of the nasal bones and therefore outpatient attendance was necessary.

  3. The Phosphodiesterase 4 Inhibitor Prevents Antigen-induced Biphasic Nasal Obstruction in Brown Norway Rats

    Directory of Open Access Journals (Sweden)

    Hirokazu Kawasaki

    2005-01-01

    Conclusions: The present study provides a simple model of allergic biphasic nasal obstruction in BN rats, and also suggests that the PDE4 inhibitor may alleviate nasal obstruction in patients with allergic rhinitis.

  4. NORMAL GENE EXPRESSION IN MALE F344 RAT NASAL TRANSITIONAL/RESPIRATORY EPITHELIUM

    Science.gov (United States)

    Abstract The nasal epithelium is an important target site for chemically-induced toxicity and carcinogenicity in rodents. Gene expression profiles were determined in order to provide normal baseline data for nasal transitional/respiratory epithelium from healthy rats. Ce...

  5. Nasal biopsies of children exposed to air pollutants.

    Science.gov (United States)

    Calderón-Garcidueñas, L; Rodriguez-Alcaraz, A; Valencia-Salazar, G; Mora-Tascareño, A; García, R; Osnaya, N; Villarreal-Calderón, A; Devlin, R B; Van Dyke, T

    2001-01-01

    Southwest Metropolitan Mexico City (SWMMC) atmosphere is a complex mixture of air pollutants, including ozone, particulate matter, and aldehydes. Children in SWMMC are exposed chronically and sequentially to numerous toxicants, and they exhibit significant nasal damage. The objective of this study was to assess p53 accumulation by immunohistochemistry in nasal biopsies of SWMMC children. We evaluated 111 biopsies from 107 children (83 exposed SWMMC children and 24 control children residents in a pollutant-compliant Caribbean island). Complete clinical histories and physical examinations, including an ear-nose-throat (ENT) exam were done. There was a significant statistical difference in the upper and lower respiratory symptomatology and ENT findings between control and exposed children (p < 0.001). Control children gave no respiratory symptomatology in the 3 months prior to the study; their biopsies exhibited normal ciliated respiratory epithelium and were p53-negative. SWMMC children complained of epistaxis, nasal obstruction. and crusting. Irregular areas of whitish-gray recessed mucosa over the inferior and middle turbinates were seen in 25% of SWMMC children, and their nasal biopsies displayed basal cell hyperplasia, decreased numbers of ciliated and goblet cells, neutrophilic epithelial infiltrates, squamous metaplasia. and mild dysplasia. Four of 21 SWMMC children with grossly abnormal mucosal changes exhibited strong transmural nuclear p53 staining in their nasal biopsies (p 0.005, odds ratio 26). In the context of lifetime exposures to toxic and potentially carcinogenic air pollutants, p53 nasal induction in children could potentially represent. a) a checkpoint response to toxic exposures, setting up a selective condition for p53 mutation, or b) a p53 mutation has already occurred as a result of such selection. Because the biological significance of p53 nuclear accumulation in the nasal biopsies of these children is not clear at this point, we strongly

  6. Preoperative CT evaluation on nasal cavity for transsphenoidal approach

    International Nuclear Information System (INIS)

    Saeki, Naokatsu; Yamaura, Akira; Hoshi, Seiichiro; Sunada, Souichi; Sunami, Kenro

    1997-01-01

    Preoperative bone CT scans sliced parallel to the surgical plane were evaluated in 32 cases of transsphenoidal surgery. This method predicted patients with narrow nasal cavity, and helped to determine the rhinological maneuvers for providing a wider operative field. In addition, it helps to plan the need and extent of sella floor removal in re-operated cases. There was relatively little difference in the width and length of the nasal cavity between acromegalic and non-acromegalic patients. Hence, bone CT scans are useful in the preoperative evaluation of patients undergoing transsphenoidal surgery. (author)

  7. Nasal heterotopia versus pilocytic astrocytoma: A narrow border.

    Science.gov (United States)

    Ellouze, N; Born, J; Hoyoux, C; Michotte, A; Retz, C; Tebache, M; Piette, C

    2015-08-01

    Failure of the anterior neuropore can lead to three main types of anomalies: nasal dermal sinus, encephalocele and nasal glioma or heterotopia. In this report, we describe a case of intracranial and extracranial glial heterotopia that probably resulted from a common failure of anterior neuropore development. We describe the prenatal radiological assessment based on ultrasound and MRI results, and consider their limitation for early fetal diagnosis. We also discuss the embryogenesis and the possible pathogenic mechanisms involved. Copyright © 2015 Elsevier Masson SAS. All rights reserved.

  8. Mometasone furoate nasal spray for the treatment of asthma

    DEFF Research Database (Denmark)

    Meteran, Howraman; Backer, Vibeke

    2016-01-01

    are the key stone in the treatment of both diseases. Mometasone furoate is a potent synthetic steroid with a very high receptor affinity and a low bioavailability and shown to be superior compared to other inhaled corticosteroids. It is not clear whether the use of mometasone furoate nasal spray (MFNS......) is associated with an improvement in asthma control. AREAS COVERED: This current paper reviews the current knowledge on the effect of mometasone furoate nasal spray in the treatment of asthma and includes clinical trials in which both subjective and objective outcomes are assessed. EXPERT OPINION: To date, only...

  9. Nasal cycle dominance and hallucinations in an adult schizophrenic female.

    Science.gov (United States)

    Shannahoff-Khalsa, David; Golshan, Shahrokh

    2015-03-30

    Nasal dominance, at the onset of hallucinations, was studied as a marker of both the lateralized ultradian rhythm of the autonomic nervous system and the tightly coupled ultradian rhythm of alternating cerebral hemispheric dominance in a single case study of a schizophrenic female. Over 1086 days, 145 hallucination episodes occurred with left nostril dominance significantly greater than the right nostril dominant phase of the nasal cycle. A right nostril breathing exercise, that primarily stimulates the left hemisphere, reduces symptoms more quickly for hallucinations. Copyright © 2015 Elsevier Ireland Ltd. All rights reserved.

  10. Nasal Cancer in the Northamptonshire Boot and Shoe Industry

    Science.gov (United States)

    Acheson, E. D.; Cowdell, R. H.; Jolles, B.

    1970-01-01

    A survey of the incidence of nasal cancer in Northamptonshire during the period 1953 to 1967 is reported. Of the 46 patients with nasal cancer ascertained during the 15-year period 21 (19 males and 2 females) had been employed at some time in the boot and shoe industry. Five other cases diagnosed either before 1953 or after 1967 in persons who had worked in the boot and shoe industry in Northamptonshire were ascertained from various sources. The incidence of nasal cancer (all histological types considered together) was significantly higher in male boot and shoe operatives in Northamptonshire than in males of all occupational classes in the Cancer Register areas selected for comparison and in males working in other occupations in Northamptonshire. The excess incidence has recently given rise to the occurrence of between 1 and 2 new cases per annum in the Northamptonshire boot and shoe industry. The cases within the Northamptonshire industry occurred almost entirely in the relatively small number of workers who are exposed to the dust of the materials used in the manufacture of footwear. Possibly there are two carcinogenic factors in the industry—one related to the production of nasal adenocarcinoma, and the other to squamous and possibly other types of carcinoma in the nasal cavity and sinuses. This requires further study. Our best estimate of the latent period for the adenocarcinoma cases was 54·6 years, which is substantially longer than for the patients with squamous, transitional, and anaplastic tumours (41·7 years). We have no evidence to answer the question whether the facts are still present in the industrial environment, though undoubtedly the standards of hygiene in the industry has improved substantially since these men were first exposed. There is probably an increased risk of nasal adenocarcinoma in the footwear repairing industry, but this requires further study. Our evidence suggests that snuff taking should be considered as a possible contributory

  11. Clival chordoma manifesting as nasal bleeding. A case report

    Energy Technology Data Exchange (ETDEWEB)

    Kitai, Ryuhei; Yoshida, Kazuhiko; Kubota, Toshihiko; Sato, Kazufumi; Handa, Yuji; Kasahara, Kazuma [University of Fukui, Department of Neurosurgery, Fukui (Japan); Nakajima, Hirofumi [Tsuruga Municipal Hospital, Department of Neurosurgery, Fukui (Japan)

    2005-05-01

    Chordoma is a rare cartilaginous tumor, for which bleeding presentation is unusual. We report a case of rare hemorrhaged clival chordoma, which was diagnosed correctly by magnetic resonance imaging. A 32-year-old man presented with nasal bleeding. The tumor was totally removed via a trans-sphenoidal approach, from which the surgical specimen confirmed chordoma. Epistaxis seemed to be caused by the spreading of the intratumoral hemorrhage into the sphenoid sinus. This case demonstrates the importance of an exact differential diagnostic evaluation, including chordoma, by use of modern imaging techniques for nasal bleeding. (orig.)

  12. Clival chordoma manifesting as nasal bleeding. A case report

    International Nuclear Information System (INIS)

    Kitai, Ryuhei; Yoshida, Kazuhiko; Kubota, Toshihiko; Sato, Kazufumi; Handa, Yuji; Kasahara, Kazuma; Nakajima, Hirofumi

    2005-01-01

    Chordoma is a rare cartilaginous tumor, for which bleeding presentation is unusual. We report a case of rare hemorrhaged clival chordoma, which was diagnosed correctly by magnetic resonance imaging. A 32-year-old man presented with nasal bleeding. The tumor was totally removed via a trans-sphenoidal approach, from which the surgical specimen confirmed chordoma. Epistaxis seemed to be caused by the spreading of the intratumoral hemorrhage into the sphenoid sinus. This case demonstrates the importance of an exact differential diagnostic evaluation, including chordoma, by use of modern imaging techniques for nasal bleeding. (orig.)

  13. Alphamimetic effects at the nasal mucosa in the MR tomogram

    International Nuclear Information System (INIS)

    Benammar-Englmaier, M.; Hallermeier, J.K.; Englmaier, B.

    1990-01-01

    The effect of xylometazolin spray (OTRIVEN) on the nasal mucosa was tested on persons with and without clinical signs of rhinitis and sinusitis. MRI is an excellent means to show the decongestive effect. The reaction is chiefly seen at the inferior and middle nasal concha and becomes manifest in a few minutes. No significant effect is noticeable at the maxillary sinus mucosa and infiltrated ethmoidal sinus. Generally, it is possible to show and examine the pharmacological effects that change the size and the liquid consistency of organs. (orig.) [de

  14. Wir zeigen andere Bilder von Frauen ...

    Directory of Open Access Journals (Sweden)

    Bettina Rulofs

    2010-03-01

    Full Text Available Der vorliegende Beitrag beleuchtet die Bedeutung der Geschlechterordnung im Prozess der sportmedialen Kommunikation. Im Kern geht es um die Frage, inwiefern im Prozess der medialen Vermittlung von Sport traditionelle Geschlechterstereotype aufrechterhalten werden oder Möglichkeiten der Irritation solcher Stereotype bestehen. Dazu werden verschiedene Ebenen des massenmedialen Kommunikationsprozesses in den Blick genommen: die Medienprodukte, die Öffentlichkeitsarbeit und Selbst-Präsentation der Sportler/innen, die Medienrezeption und die Herstellungsprozesse von Medien in den Sportredaktionen. This article illustrates the relevance of gender in processes of sports media communication. The question in focus is in what way traditional gender stereotypes are perpetuated in the process of media communication in sport and how such stereotypes can be irritated. Therefore different levels of mass media communication are considered: the media products, the public relations of athletes and the presentation of themselves as athletes, the media-reception and the production processes in sport departments of media institutions.

  15. The Molecular Genetics of von Willebrand Disease

    Directory of Open Access Journals (Sweden)

    Ergül Berber

    2012-12-01

    Full Text Available Quantitative and/or qualitative deficiency of von Willebrand factor (vWF is associated with the most common inherited bleeding disease von Willebrand disease (vWD. vWD is a complex disease with clinical and genetic heterogeneity. Incomplete penetrance and variable expression due to genetic and environmental factors contribute to its complexity. vWD also has a complex molecular pathogenesis. Some vWF gene mutations are associated with the affected vWF biosynthesis and multimerization, whereas others are associated with increased clearance and functional impairment. Moreover, in addition to a particular mutation, type O blood may result in the more severe phenotype. The present review aimed to provide a summary of the current literature on the molecular genetics of vWD.

  16. The molecular genetics of von Willebrand disease.

    Science.gov (United States)

    Berber, Ergül

    2012-12-01

    Quantitative and/or qualitative deficiency of von Willebrand factor (vWF) is associated with the most common inherited bleeding disease von Willebrand disease (vWD). vWD is a complex disease with clinical and genetic heterogeneity. Incomplete penetrance and variable expression due to genetic and environmental factors contribute to its complexity. vWD also has a complex molecular pathogenesis. Some vWF gene mutations are associated with the affected vWF biosynthesis and multimerization, whereas others are associated with increased clearance and functional impairment. Moreover, in addition to a particular mutation, type O blood may result in the more severe phenotype. The present review aimed to provide a summary of the current literature on the molecular genetics of vWD. None declared.

  17. von Neumann's hypothesis concerning coherent states

    International Nuclear Information System (INIS)

    Zak, J

    2003-01-01

    An orthonormal basis of modified coherent states is constructed. Each member of the basis is an infinite sum of coherent states on a von Neumann lattice. A single state is assigned to each unit cell of area h (Planck constant) in the phase plane. The uncertainties of the coordinate x and the square of the momentum p 2 for these states are shown to be similar to those for the usual coherent states. Expansions in the newly established set are discussed and it is shown that any function in the kq-representation can be written as a sum of two fixed kq-functions. Approximate commuting operators for x and p 2 are defined on a lattice in phase plane according to von Neumann's prescription. (leeter to the editor)

  18. Theodor von Grotthuss’ Contribution to Electrochemistry

    International Nuclear Information System (INIS)

    Pauliukaite, Rasa; Juodkazytė, Jurga; Ramanauskas, Rimantas

    2017-01-01

    Freiherr Christian Johann Dietrich Theodor von Grotthuss (1785-1822) lived and worked in Lithuania. Inspired by Volta's pile he proposed the first theory of water electrolysis, which was published in 1805 in Rome. Michael Faraday acknowledged T. Grotthuss for this theory in his further investigations of electrolysis processes. Having studied in Germany and France Grotthuss brought science to province by establishing his laboratory in Gedučiai village in his mother's real estate. Lithuanian scientists are proud that life of Theodor von Grotthuss was related to this country. Many events to remember this prominent scientist are organised in Vilnius and other places. His works and example provided a good basis for further development of electrochemical science in Lithuania. Grotthuss insights into the mechanism of proton transport still are of great relevance to such areas of modern science as membrane biochemistry, energy conversion and storage.

  19. Inattentional blindness and the von Restorff effect.

    Science.gov (United States)

    Schmidt, Stephen R; Schmidt, Constance R

    2015-02-01

    Sometimes we fail to notice distinctive or unusual items (inattentional blindness), while other times we remember distinctive items more than expected items (the von Restorff effect). A three-factor framework is presented and tested in two experiments in an attempt to reconcile these seemingly contradictory phenomena. Memory for different types of unexpected stimuli was tested after an easy or difficult Stroop color-naming task. Highly arousing taboo words were well remembered even when the difficult Stroop task limited attentional resources. However, a conceptual isolation effect was only observed when the nature of the category change was highlighted by the Stroop task, the Stroop task was easy, and/or the isolated targets enjoyed a retrieval advantage relative to comparison targets. As proposed in the three-factor framework, the arousing qualities of the stimuli, the attentional demands of the primary task, and the relevance of isolated features at encoding and retrieval combine to produce inattentional blindness and the von Restorff effect.

  20. Verbesserung der Symmetrie von Hirnaufnahmen entlang der Sagittalebene

    Science.gov (United States)

    Ens, Konstantin; Wenzel, Fabian; Fischer, Bernd

    Die lokale Symmetrie von Hirnscans entlang der Sagittalebene zu ermitteln und zu modizifieren, ist für eine Reihe neurologischer Anwendungen interessant. Beispielsweise kann der voxelweise Vergleich von rechter und linker Hirnhälfte nur dann Aufschluss über die Lokalisierung von Läsionen geben, wenn durch Transformation ein Hirnscan eine möglichst hohe Symmetrie aufweist. Ein weiteres Anwendungsgebiet ist die Visualisierung von medialen Hirnschnitten, für die die Trennfläche beider Hirnhälfte möglichst eben sein sollte. Diese Arbeit stellt die Entwicklung eines Verfahrens vor, mit dessen Hilfe die Symmetrie von Hirnaufnahmen entlang der Sagittalebene verbessert werden kann. Dies geschieht unter Verwendung von aktiven Konturen, die mit Hilfe einer neuartigen Kostenfunktion gesteuert werden. Experimente am Ende der Arbeit mit strukturellen Kernspinaufnahmen demonstrieren die Leistungsfähigkeit des Verfahrens.