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  1. Flexibilitätsbasierte Gestaltung der logistischen Auftragsabwicklung – Anwendung am Beispiel von Produktionsdienstleistern

    OpenAIRE

    Teich, Enrico

    2014-01-01

    Zur Bewältigung von Belastungsschwankungen in der industriellen Produktion – der systematischen Regelung von Kapazitätsangebot und -bedarf – existieren Methoden in der logistischen Auftragsabwicklung, deren Anwendungserfolg von den im Produktionsbereich vorhandenen Kapazitäts- und Belastungsflexibilitätsmaß abhängig ist. Die Entwicklung geeigneter Verfahren zur Messung dieser Flexibilitätstypen als auch von Ansätzen zur Nutzung der Messwerte bei der Gestaltung der logistischen Auftragsabwickl...

  2. Attitudes: changing the atmosphere : zur Theorie und Anwendung der Einstellungs-Verhaltens-Modelle von Martin Fishbein und Icek Ajzen in der allgemeinen und speziell der ökologieorientierten Markt- und Sozialforschung

    OpenAIRE

    Götze, Stephan

    2010-01-01

    Die Arbeit fokusiert zum einen das Innovationspotenzial der Einstellungs-Verhaltens-Modelle von Martin Fishein und Icek Ajzen, zum anderen zeigt sie deren Theorie und Anwendung in der allgemeinen und speziell der ökologieorientierten Markt- und Sozialforschung. In 8 verschiedenen Kapiteln wird die Forschungsgeschichte, die Imageforschung, Marketing und Research für die Umwelt, das Marktpotenzial für den ökologischen Landbau, das Marktpotenzial für Kunststoff-Recycling sowie die Anwendung der...

  3. Die Mikroökonomie von Finanzkrisen. Eine Anwendung auf den Euroraum.

    Directory of Open Access Journals (Sweden)

    Dominik Bernhofer

    2014-09-01

    Full Text Available Diese Studie untersucht die Auslandsforderungen der an die BIZ meldenden transnationalen Banken gegenüber den Euroraumländern seit dem Bankrott von Lehman Brothers; dabei soll der Rückgang dieser Forderungen in einem einfachen Modell multipler Gleichgewichte erklärt werden. Die Analyse legt den Schluss nahe, dass es für die betreffenden Banken rational war, die Euroraum-Peripherie an den Rand des Bankrotts zu treiben, und dass mutige wirtschaftspolitische Entscheidungen einen wichtigen Beitrag zur Stabilisierung der nachteiligen ökonomischen Konsequenzen geleistet haben. Solidarität zwischen den Euroraumländern erscheint in diesem Modell als wichtigste Voraussetzung für integrierte Finanzmärkte, weil sie das Auftreten von Koordinationsversagen zwischen transnationalen Banken verhindert und damit Finanzstabilität gewährleistet.

  4. Stickstoff-Funktionalisierung von CNFs und seine Anwendung in der Heterogenen Katalyse

    OpenAIRE

    R. Arrigo

    2009-01-01

    Die Notwendigkeit der Entwicklung selektiver und aktiver heterogenen Katalysatoren hat zur Suche nach neuen synthetischen Strategien geführt, um die sehr spezifische chemische Struktur von Bio-Systemen nachzuahmen. Durch ihre unvergleichliche Eignung für chemische Funktionalisierung, stellen nanostrukturierte Kohlenstoffe ein ideales organisches Substrat dar, dessen Oberflächenchemie entsprechend der spezifischen Bedürfnisse angepasst werden kann. In dieser Arbeit wurde Stickstoff Funktionali...

  5. Anwendung von Methoden der Logistik und Netzplantechnik zur präzedenz- und ressourcenbeschränkten Ablaufplanung von Echtzeitsystemen

    Science.gov (United States)

    Gumzej, Roman; Lipičnik, Martin

    Grundlegende Zusammenhänge zwischen Logistik, Netzplantechnik und Echtzeit sowie den zugehörigen Arten der Ablaufplanung und ihrer Nutzung werden dargestellt. Das Echtzeitprinzip beinhaltet Rechtzeitigkeit von Abläufen, wobei es für eine frühzeitige Beendigung eines Ablaufs keinen Bonus gibt; im Gegensatz zum verspäteten Ablauf, dessen Konsequenzen in der Regel negativ und unabschätzbar sind. Das Just-in-Time-Prinzip gleicht dem der Echtzeit und wird vor allem in der Logistik zur Bezeichnung reibungsloser Abläufe in Beschaffungsketten verwendet. In der Netzplantechnik werden die kritischen Aktivitäten binnen eines Projektes bestimmt, die nicht verzögert werden dürfen, um das Projekt rechtzeitig zu beenden. Außerdem haben die drei Bereiche noch eine Gemeinsamkeit: um realistische Ablaufszenarien darzustellen, müssen in den Analysen auch begrenzte Ressourcen angemessen berücksichtigt werden.

  6. Anwendung des Comet Assay (Einzelzell-Gelelektrophorese) an Zellen von Fischen zum Nachweis gentoxischer Wirkungen im aquatischen Biomonitoring

    OpenAIRE

    2013-01-01

    Gewässer sind Lebensgrundlage, jedoch gleichzeitig Schadstoffsenken für eine Vielzahl von Kontaminanten. Biologische Wirkungstests und das Biomonitoring aquatischer Proben sind daher besonders wichtig, um Umwelt-Gefahrenpotenziale erkennen zu können. Der "Comet Assay" (Einzelzell-Gelelektrophorese) ist ein Indikator von DNA-Strangbrüchen und wurde hier als Test auf gentoxische Wirkungen erprobt und angewandt. Mit bekannten, gentoxischen Substanzen wurden Nachweisgrenzen und Dosis-Wirkungs-Be...

  7. Primäre lokalisierte Amyloidose der Harnblase – Ein Fallbericht über die intravesikale Anwendung von Dimethylsulfoxid (DMSO

    Directory of Open Access Journals (Sweden)

    Heidler S

    2015-01-01

    Full Text Available Als Amyloidose bezeichnet man die Anreicherung von abnorm veränderten Proteinen im Interstitium, welche systemisch oder lokalisiert erfolgen kann. Bei der primären Amyloidose ist die Ursache unbekannt, die sekundäre Amyloidose tritt in Zusammenhang mit chronischen entzündlichen Erkrankungen auf. Die primäre Amyloidose der Harnblase ist eine seltene Erkrankung, als Symptome sind eine schmerzlose Hämaturie und imperativer Harndrang bekannt. Als Therapiestandard hat sich eine transurethrale Resektion der Amyloidoseherde etabliert sowie alternativ als Prophylaxe die intravesikale Instillation von Dimethylsulfoxid.

  8. Experimentelle und klinische Anwendung von Botulinumtoxin A im autonomen und muskulären System im Kopf-Hals-Bereich

    OpenAIRE

    Rohrbach-Volland, Saskia

    2014-01-01

    In the region of the head and neck, botulinum toxin - through its anticholinergic effect - is a suitable therapeutic option in the muscular and the autonomic nervous system concerning different dysfunctions. Respecting some special aspects, it is an effective treatment for disorders like dystonias, spasm, synkinesia, hypersalivation, nasal hypersecretion, gustatory sweating and others with very few side-effects. The positive therapeutic effect is temporarly limited, so that the patients need...

  9. Primäre lokalisierte Amyloidose der Harnblase Ein Fallbericht über die intravesikale Anwendung von Dimethylsulfoxid (DMSO)

    OpenAIRE

    2015-01-01

    Als Amyloidose bezeichnet man die Anreicherung von abnorm veränderten Proteinen im Interstitium, welche systemisch oder lokalisiert erfolgen kann. Bei der primären Amyloidose ist die Ursache unbekannt, die sekundäre Amyloidose tritt in Zusammenhang mit chronischen entzündlichen Erkrankungen auf. Die primäre Amyloidose der Harnblase ist eine seltene Erkrankung, als Symptome sind eine schmerzlose Hämaturie und imperativer Harndrang bekannt. Als Therapiestandard hat sich eine transurethrale R...

  10. Zur 'Ansteckungswirkung' von Gewalt gegenüber Ausländern : Anwendung eines Schwellenwertmodells kollektiven Verhaltens

    OpenAIRE

    1992-01-01

    'In diesem Aufsatz geht es um die theoretische Erklärung gewalttätiger Anschläge gegenüber Ausländern in Deutschland nach der Wiedervereinigung. Dabei sollen die beiden folgenden Fragen beantwortet werden: 1. Unter welchen Bedingungen kommt es zu derartigen Anschlägen auf der Mikroebene einzelner Akteure? 2. Wie kommt es zu einem sprunghaften Anstieg von Gewalt auf der gesamtgesellschaftlichen Makroebene? Zur Beantwortung dieser Fragen werden ein Attitüden- und ein Schwellenwertmodell kollekt...

  11. Effects of platinum in biological systems - toxicology and pharmaceutical applications; Wirkungen von Platin in biologischen Systemen - Toxikologie und pharmazeutische Anwendung

    Energy Technology Data Exchange (ETDEWEB)

    Nachtigall, D. [Fraunhofer-Institut fuer Toxikologie und Aerosolforschung, Hannover (Germany)

    1997-12-31

    The title of this lecture has intentionally been worded rather vaguely with ``biological systems`` to do justice to the fact that there are meanwhile extensive data available on diverse levels of the toxicology and structure-effect relationships of some platinum compounds. These range from epidemiological descriptions over toxicity studies to molecular biological reaction mechanisms. Any discussion on the toxicity of a substance implies that the substance poses a direct or indirect hazard to humans. In the case of platinum and its compounds there are three main categories of exposure: platinum production including workplaces in the platinum processing industries; clinical treatment with antineoplastic platinum-containing agents; and, finally, the environment, where platinum levels are known to be rising since some years. The association between these exposures becomes clear when one considers the platinum pollution caused by automobile catalytic converters, hospital effluents, and by platinum-containing industrial products in the widest sense. [Deutsch] Der Titel des Vortrages ist mit `biologischen Systemen` sehr allgemein gehalten, da ueber die Toxikologie und die Struktur-Wirkungsbeziehungen einiger Platinverbindungen auf den verschiedensten Ebenen umfangreiche Daten vorliegen. Diese reichen von epidemiologischen Beschreibungen ueber Toxizitaetsstudien bis hin zu molekularbiologischen Reaktionsmechanismen. Die Diskussion um die Toxizitaet von Substanzen impliziert immer die direkte oder indirekte Gefaehrdung des Menschen. Im Falle des Platins und seiner Verbindungen existieren drei wesentliche Expositionsbereiche: Die Platingewinnung sowie die Arbeitsplaetze in der Platin verarbeitenden Industrie, die klinische Behandlung mit antineoplastischen Platinwirkstoffen und schliesslich die Umwelt, in der seit einigen Jahren ansteigende Platinkonzentrationen verzeichnet werden. Die Verbindung zwischen diesen Bereichen wird deutlich, wenn man die Platinimmissionen durch

  12. The use of plastics for belt and chain drives in primary drives of combustion engines; Die Anwendung von Kunststoffen in Riemen- und Kettentrieben bei Primaerantrieben von Verbrennungsmotoren

    Energy Technology Data Exchange (ETDEWEB)

    Leeuwen, P. van

    1999-07-01

    It can be observed that chain drives are again used more often in engines than belt drives. There are several reasons: long durability, higher power transmission is possible, no service necessary, small construction space and low cost (?) depending on comfort aspects (noise). Polyamides, especially PA 46 have proved themselves for a long time as ideal material for slide and guide rails. The combination of dimensional stability under heat, stiffness and wear behaviour combined with the low cost must be emphasised. The development of slide and guide rails is far from being completed. Here the known specific advantages of plastics apply, i.e. the integration of functions into one component with an almost unlimited freedom of design. (orig.) [German] Grundsaetzlich ist der Trend zu beobachten, dass Kettenantriebe in modernen Motoren zu Lasten der Riemenantriebe wieder weitere Verbreitung finden. Gruende hierfuer sind: Lange Lebensdauer, hoehere Kraefteuebertragung moeglich, kein Service notwendig, geringerer Bauraum und Kosten (?) in Abhaengigkeit der Komfortaspekte (Geraeusche). Polyamide, insbesondere PA 46, haben sich seit langer Zeit bewaehrt als idealer Werkstoff fuer Spann- und Fuehrungsschienen. Besonders herauszustellen ist hier die Kombination von Waermeformbestaendigkeit, Steifigkeit und Verschleissverhalten unter Kostenaspekten. Die Entwicklung von Spann- und Fuehrungsschienen ist noch lange nicht abgeschlossen. Hier kommen die bekannten spezifischen Vorteile von Kunststoffen zur Geltung, d.h. Integration von Funktionen in einem Bauteil mit nahezu unbegrenzter Gestaltungsfreiheit. (orig.)

  13. Anwendung von Hydroxyethylstärke 200/0.5 (Infukoll HES 10%) bei gesunden Pferden und Pferden mit Kolik oder akuter Kolitis

    OpenAIRE

    Rieckhoff, Karin

    2004-01-01

    In einer kontrollierten Studie an gesunden Pferden wurde die Pharmakokinetik von Infukoll HES 10% untersucht und dessen klinische Wirksamkeit in unterschiedlichen Dosierungen mit der von isotoner und hypertoner NaCl-Lösung verglichen. In einer darauffolgenden prospektiven klinischen Untersuchung an Pferden mit akuter Kolitis oder Ileus konnte die Wirksamkeit des Plasmaexpanders am Pferdepatienten dokumentiert werden. Die Versuchsgruppe, bestehend aus 6 Warmblut-Stuten, nahm an 5 Versuchsreihe...

  14. Service-life monitoring of heat-exposed pipe lines. Pt. 2. Application in the power station; Lebensdauerueberwachung von warmgehenden Rohrleitungen. T. 2. Anwendung im Kraftwerk

    Energy Technology Data Exchange (ETDEWEB)

    Maile, K.; Purper, H.; Rohler, K.; Bietenbeck, F.; Fischer, B.

    1994-12-31

    The authors point out that the testing stage has produced positive verification of the module developed for time-dependent additional forces to be included in service-life monitoring. There is a trend suggesting that additional moments obtaining in the pipeline system of the Mainz-Wiesbaden power station do not result in a significant consumption of service-life time so that the planned monitoring procedures (TRD 508) will suffice for the plant obviating the need for any additional or even premature measures to be adopted. This is indicated both by the measurement values of the service-life monitoring system and by the strains measured by HT-DMS. However, no statement can be made yet whether, the reverse assumption may be true i.e. to postpone schedulled maintenance measures to a point of time after the TRD limit (e{sub w} + e{sub z} = 60%) will have been reached due to the fact that the exhaustion of service life time will have progressed less than laid down in design calculations as a result of less operating loads. (orig.) [Deutsch] Insgesamt kann festgestellt werden, dass der entwickelte Modul zur Beruecksichtigung von zeitabhaengigen Zusatzkraeften im Rahmen dieser Testphase erfolgreich verifiziert werden konnte. Erste vorsichtige Bewertungen lassen als Tendenz erkennen, dass zusaetzliche Momente im Rohrlietungssystem des Kraftwerkes Mainz-Wiesbaden keinen signifikanten Lebensdauerverbrauch bewirken, so dass in der Anlage neben den planmaessigen Ueberwachungsprozeduren (TRD 508) keine weiteren oder gar vorzeitige Massnahmen ergriffen werden muessen. Dies resultiert sowohl aus den Messwerten des Lebensdauerueberwachungssystems als auch aus den durch die HT-DMS gemessenen Dehnungen. Ob allerdings im Umkehrschluss geplante Wartungsmassnahmen nach Erreichen der TRD-Grenze: e{sub w} + e{sub z} = 60% erst zu einem spaeteren Zeitpunkt durchgefuehrt werden koennen, weil die Zeitstanderschoepfung infolge geringerer Betriebsbelastungen weniger fortgeschritten ist als

  15. Reactive liquid/liquid extraction of heavy metals from landfill seepage waters. Its characterisation and application; Reaktive fluessig/fluessig Extraktion von Schwermetallen aus Deponiesickerwasser. Charakterisierung und Anwendung

    Energy Technology Data Exchange (ETDEWEB)

    Woller, N.

    1994-06-01

    This study demonstrates the applicability of liquid-liquid extraction by means of the commercial complexers LIX26{sup R} and LIX84{sup R} to heavy metal removal from waste waters. The composition of this oil-soluble complex is MeR{sub 2}, where Me denotes Hg{sup 2+}, Cd{sup 2+}, Zn{sup 2+}, Cu{sup 2+}, and Ni{sup 2+}, and R denotes LIX84{sup R}. This composition makes the complex electrically neutral, and all polar groups are located inside the molecule. The extraction efficiency of the complexer LIX84{sup R} for the various metal ions is evident in the succession Cu{sup 2+}, Ni{sup 2+} >> Zn{sup 2+} > Hg{sup 2+} > Cd{sup 2+}. These heavy metal ions are even readily extractable at chloride concentrations of up to 1 mol/l. As the structure of the complexer is that of an oil-soluble surfactant with complexing properties, it accumulates at the phase boundary between oil and water. Measurement of interfacial tension in various solvent systems showed that the polar solvent chloroform permits only a weak accumulation of the complexer (400 nmol/m{sup 2}), whereas the unpolar solvent kerosine permits greater accumulation specifically on the water side of the phase boundary (1958 nmol/m{sup 2}). Organic solvents solvate the complexer so well, that it is even removed from the air side of the phase boundary. The differing accumulation of the complexer at the water/oil phase boundary explains the differing increase of phase separation time for polar and unpolar solvents. (orig.) [Deutsch] In dieser Arbeit wird unter Verwendung der handelsueblichen Komplexbildner LIX26{sup R} und LIX84{sup R} die Anwendbarkeit der reaktiven fluessig-fluessig Extraktion auf die Entfernung von Schwermetallen aus Abwaessern gezeigt. Der oelloesliche Komplex hat die Zusammensetzung MeR{sub 2} fuer Me = Hg{sup 2+}, Cd{sup 2+}, Zn{sup 2+}, Cu{sup 2+} und Ni{sup 2+} sowie R = LIX84{sup R}. Dieser Komplex ist aufgrund seiner Zusammensetzung elektrisch neutral und alle polaren Gruppen des Komplexes

  16. Small specimen test results and application of advanced models for fracture mechanics assessment of RPV integrity; Ergebnisse von Kleinproben und Anwendung von Modellansaetzen zur bruchmechanischen Bewertung der RDB-Integritaet

    Energy Technology Data Exchange (ETDEWEB)

    Keim, Elisabeth; Huemmer, Matthias [AREVA NP GmbH (Germany); Hoffmann, Harald [VGB (Germany); Nagel, Gerhard [e-on Kernkraft (Germany); Kuester, Karin [VENE (Germany); Koenig, Guenter; Ilg, Ulf [EnBW (Germany); Widera, Martin [RWE (Germany); Rebsamen, Daniel [KKW Goesgen (Germany)

    2008-07-01

    For the RPV (reactor pressure vessel) integrity assessment the transferability of specimen test results to components is of main importance. The international project TIMES (transferability of fracture toughness of irradiated materials to components and structures) is focussed on the transferability of fracture mechanical characteristics of irradiated materials to components or structures, in order to allow the quantification of differences between sample and component characteristics based on experiments and calculations. The studies were performed for the brittle and brittle-ductile regions of the material characteristics using specimens from original RPV materials in different conditions. Based on case studies the consequence of a component assessment with postulated defects are shown when specimen-related materials properties are used. Since it is not possible to prove the transferability for an RPV in detail, component-similar effects were investigated that allow in combination with numerical modelling to quantify the safety margin. Samples and experimental procedures were developed that simulated the real component situation. The effects of crack depth and multiaxial loads, relevant for real components, were investigated with these samples. A micromechanical model was developed based on the weakest link theory and the statistical failure probability; this model is used for the prediction of fracture toughness of samples and components with defects. For a component with postulated defects the safety margin was assessed using different methodologies, based on standard fracture mechanical samples, taking into account component specific aspects. [German] Fuer die Bewertung der RDB-Integritaet ist die Uebertragbarkeit von Probenkennwerten auf Bauteile von grosser Bedeutung. Dazu wurde das Projekt ''TIMES'' - ein internationales Projekt zur Uebertragbarkeit von Bruchzaehigkeitskennwerten von bestrahlten Materialien auf Komponenten und Strukturen - durchgefuehrt, um

  17. Mobile Commerce - Anwendung und Perspektiven

    OpenAIRE

    Turowski, Klaus

    2003-01-01

    Mobile Commerce - Anwendung und Perspektiven / 3. Workshop Mobile Commerce, Universität Augsburg, 4.2.2003. Key Pousttchi ... Hrsg.). - Bonn : Ges. für Informatik, 2003. - 142 S. - (GI-Edition : Proceedings ; 25)

  18. Status report on R 22 phase-out in refrigeration engineering. With recommendations for decision-makers in politics, economy, research and development; Derzeitige Erkenntnisse zum Ausstieg aus der Anwendung von R 22 als Kaeltemittel in der Kaelte- und Klimatechnik. Mit Empfehlungen an Entscheidungstraeger in Politik, Wirtschaft, Forschung und Entwicklung

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1997-08-01

    There is no standard substitute for R 22, especially in older systems. The authors therefore investigated mixtures of refrigerant fluids whose properties can be modified so as to resemble R 22. The emphasis was on safety of use and low energy consumption. Of the mixtures proposed, R 407C and R 410A are the most promising. However, the use of R 407C necessitates optimisation of refrigerator components while R 410A in many cases necessitates the development of new components. Considerable development efforts are still required before wide-spread application of these two refrigerant mixtures can be envisaged. Further options for new refrigeration systems are: R 134a, R 404A, R 407A, R 507, Isceon 59, R 290 (propane), R 1270 (propene), and R 717 (ammonia). (orig./GL) [Deutsch] Fuer den Ersatz von R 22 ist aus technischer Sicht kein einheitliches Kaeltemittel verfuegbar wie beim Ersatz von R 12 durch das Kaeltemittel R 134a. Insbesondere fuer Altanlagen, die mit R 22 betrieben werden, existiert nur in einigen wenigen Faellen die Moeglichkeit, sogenannte `drop in-Kaeltemittel` einzusetzen. Mangels geeigneter Einstoffkaeltemittel als Ersatz fuer R 22 wurden und werden Kaeltemittelgemische untersucht, die in ihren Eigenschaften dem zu ersetzenden R 22 angepasst wurden. Hierbei wurde insbesondere versucht, das Sicherheitsrisiko und den Energieverbrauch der kaeltetechnischen Anwendung nicht zu erhoehen. Aus den zahlreichen vorgeschlagenen Gemischen kristallisieren sich derzeit die Kaeltemittel R 407C und R 410A als die erfolgversprechendsten Kandidaten heraus. Der Einsatz des Kaeltemittelgemisches R 407C erfordert die Optimierung von kaeltetechnischen Komponenten. Fuer den Einsatz des Kaeltemittels R 410A muessen dagegen vielfach neue Komponenten entwickelt werden. Fuer eine breite Anwendung dieser beiden Kaeltemittelgemische besteht jedoch noch erheblicher Entwicklungsbedarf. Neben diesen Kaeltemittelgemischen gibt es weitere Optionen fuer Neuanlagen; hierzu zaehlen im

  19. Ribosomal studies on the 70S ribosome of E.coli by means of neutron scattering; Strukturuntersuchungen am 70S-Ribosom von E.coli unter Anwendung von Neutronenstreuung

    Energy Technology Data Exchange (ETDEWEB)

    Burkhardt, N. [GKSS-Forschungszentrum Geesthacht GmbH (Germany). Inst. fuer Werkstofforschung

    1997-12-31

    Neutronenstreuung liefern. Durch den Austausch des natuerlichen Wasserstoffs ({sup 1}H) gegen Deuterium ({sup 2}H) lassen sich Teilstrukturen des Komplexes fuer Neutronen kontrastieren und direkt in situ vermessen. Im Rahmen der vorliegenden Arbeit wurden solche deuterium-markierten Ribosomenpraeparate (E. coli) hergestellt und mit Neutronen analysiert. Die erforderlichen biochemischen Methoden wurden etabliert und zu einem allgemein anwendbaren Praeparationssystem zusammengefasst. Es koennen damit alle Komponenten des 70S-Ribosoms in beliebiger Kombination markiert werden. Auf der Grundlage einer systematischen Analyse der Protein- und RNA-Phasen konnte ein neues 70S-Ribosomenmodell entwickelt werden, das nicht nur die aeussere Form des Partikels beschreibt, sondern erstmals auch eine vermessene interne Protein-RNA-Verteilung und den Verlauf der Untereinheitengrenze angibt (Vierphasen-Modell; Aufloesung: 50 A). 70S-Ribosomenmodelle aus anderen Studien wurden anhand der gemessenen Streudaten beurteilt und gewichtet. Mit Hilfe einer neuen, besonders empfindlichen Neutronenstreutechnik, der Protonenspin-Kontrastvariation, gelang es ausserdem, einzelne markierte Proteine zu vermessen und zu lokalisieren. Mit den Positionen von S6 und S10 werden die ersten im 70S-Ribosom vermessenen Proteinschwerpunktskoordinaten vorgelegt. (orig.)

  20. Fracture-mechanical analysis of metal/ceramic composites for applications in high-temperature fuel cells (SOFC); Bruchmechanische Untersuchung von Metall/Keramik-Verbunsystemen fuer die Anwendung in der Hochtemperaturbrennstoffzelle (SOFC)

    Energy Technology Data Exchange (ETDEWEB)

    Kuhn, Bernd Josef

    2008-08-25

    The author investigated the deformation and damage behaviour of soldered ceramic/metal joints in SOFC stacks, using thermochemical methods. Methods for analyzing sandwich systems and for mechanical characterization of joints were adapted and modified in order to provide fundamental understanding of the mechanical properties of soldered joints. [German] In dieser Arbeit wurde das Verformungs- und Schaedigungsverhalten von Keramik/ Metall-Loetverbindungen fuer SOFC-Stacks thermomechanisch untersucht. Verfahren zur Analyse von Schichtsystemen und fuer die mechanische Charakterisierung von Fuegeverbindungen wurden adaptiert und weiterentwickelt, um zu einem grundlegenden Verstaendnis der mechanischen Eigenschaften von Loetverbindungen zu gelangen.

  1. Clemens Diesbergen: Radikal-konstruktivistische Pädagogik als problematische Konstruktion. Eine Studie zum Radikalen Konstruktivismus und seiner Anwendung in der Pädagogik. Frankfurt a.M./Bern: Lang 1998. [Rezension

    OpenAIRE

    Benner, Dietrich

    1999-01-01

    Rezension von: Clemens Diesbergen: Radikal-konstruktivistische Pädagogik als problematische Konstruktion. Eine Studie zum Radikalen Konstruktivismus und seiner Anwendung in der Pädagogik. Frankfurt a.M./Bern: Lang 1998. 318 S.

  2. Charakterisierung von Radiolyseprodukten in gammabestrahlten Polyamiden Thermodesorption-Gaschromatographie Massenspekroskopie

    OpenAIRE

    Selmi, Hany

    2008-01-01

    Der Verbrauch von Polyamiden in allen technischen Bereichen, darunter im Bereich der Verpackung von Lebensmitteln sowie im Bereich der Herstellung von medizinischen Artikeln und Geräten steigt stetig an. Dies beruht auf ihren Eigenschaften wie hohe Festigkeit, ausgezeichnete Thermoformbarkeit, hohe Wärmeformbeständigkeit, Sterilisierbarkeit und sehr gute Barriereeigenschaften gegen Gase, insbesondere gegenüber Sauerstoff und Aromen. Die Anwendung von Gammastrahlen zur Sterilisation von Verpac...

  3. Clinical application of leucocyte scintigraphy with the monoclonal antibody MAK BW 250/183 with special regard to the induction of antimurine antibodies (HAMA); Leukozytenszintigraphie mit dem monoklonalen Antikoerper MAK BW 250/183 in der klinischen Anwendung unter Beruecksichtigung der Induktion von antimurinen Antikoerpern (HAMA)

    Energy Technology Data Exchange (ETDEWEB)

    Eising, E.G. [Klinik und Poliklinik fuer Nuklearmedizin der Universitaet-GH, Essen (Germany); Reiners, C. [Klinik und Poliklinik fuer Nuklearmedizin der Universitaet-GH, Essen (Germany); Farahati, J. [Klinik und Poliklinik fuer Nuklearmedizin der Universitaet-GH, Essen (Germany); Jacob, M. [Klinik und Poliklinik fuer Nuklearmedizin der Universitaet-GH, Essen (Germany)

    1994-12-31

    Scintigraphy with the murine antibody MAK BW 250/183 (Scintimun Granulozyt{sup R}) has proven to be a good imaging method to clear up clinical questions concerning acute inflammatory processes. 30 patients with clinical signs of acute inflammation were included in this prospective study to test the clinical usefulness of this tracer and possible negative influences by anti-murine antibodies (HAMA). Side effects or induction of HAMA antibodies couldn`t be observed in any patients. The quality of the obtained images was good in all cases. However, false negative results were obtained in cases on antiphlogistic medication (e.g. cortisone) or with chronic inflammatory diseases. Application of MAK BW 250/183 (Scintimum Granulozyt{sup R}) should be avoided in children due to its relative high radiation dose to bone marrow. False negative results can be found in inflammatory lesions of axial sceleton. On the other hand, the good contrast of bone marrow can be used in patients to diagnose pathologic alterations of bone marrow distribution. (orig.) [Deutsch] Bei erwachsenen Patienten mit dem gezielten Verdacht auf akute entzuendliche Veraenderungen stellt die Anti-Granulozyten-Szintigraphie eine Methode mit relativ guter Bildgebung und Aussagefaehigkeit dar. Zur Ueberpruefung der klinischen Wertigkeit der Anti-Granulozyten-Szintrigraphie mit dem monoklonalen, murinen Antikoerper MAK BW 250/183 (Scintimun Granulozyt{sup R}) wurden 30 Patienten in einer prospektiv angelegten Studie untersucht. Insbesondere wurde hierbei auch die Ausbildung von signifikanten Antikoerpertitern gegen den MAK ueberprueft und deren Einfluss auf die szintigraphische Bildgebung evaluiert. Nebenwirkungen oder die Ausbildung von Antikoerpern (HAMA) wurden bei Patienten innerhalb der Studie nicht beobachtet. Auch die erhaltenen szintigraphischen Aufnahmen waren durchweg gut beurteilbar. Entzuendungen unter Antiphlogistika (insbesondere Cortisonpraeparate) sowie laengerfristig bestehende Entzuendungen

  4. Development and prototypical application of analysis methods for complex anion mixtures in waters and heavy metal organyls in sediments; Entwicklung und prototypische Anwendung von Analysenverfahren fuer komplexe Anionengemische in Waessern und Schwermetallorganylen in Sedimenten. Schlussbericht

    Energy Technology Data Exchange (ETDEWEB)

    Anders, B.; Knoechel, A.; Potgeter, H.; Staub, S.; Stocker, M.

    2002-07-01

    When it comes to assessing the hazards emanating from heavy pollutants in waters mere elemental analysis provides too little information. Due to the great differences in toxicity and mobility it is important to know more about the exact species in question. This is particularly true of heavy metals that form stable organyls, specifically As, Pb, Sn and Hg, but also of alkylated arsenic acids, which need to be measured in complex anion mixtures. The purpose of the present project was to develop robust, powerful analysis methods and thus overcome the existing deficit in reliable analysis methods for these substances. An important approach in this connection is the use of coupled chromatography and detection systems for separation and analysis. [German] Hinsichtlich der von einer Schwermetallbelastung in Gewaessern ausgehenden Gefahren liefert die reine Elementanalytik nur unzureichende Aussagen. Aufgrund der grossen Unterschiede in Toxiditaet und Mobilitaet ist die Kenntnis der jeweils vorliegenden Spezies bedeutungsvoll. Dies gilt in besonderem Masse fuer die stabile Organyle bildenden Schwermetalle As, Pb, Sn und Hg sowie die alkylierten Arsensaeuren, die es innerhalb komplexer Anionengemische zu bestimmen gilt. Hinsichtlich ihrer sicheren Bestimmung bestehen methodische Defizite, die das vorliegende Projekt durch die Entwicklung robuster, nachweisstarker Analysenverfahren zu beseitigen versucht. Grosse Bedeutung kommt dabei gekoppelten Systemen aus Chromatographie und Detektion als Trenn- und Bestimmungsmethode zu. (orig.)

  5. Nasal Physiology

    Science.gov (United States)

    ... Caregivers Contact ARS HOME ANATOMY Nasal Anatomy Sinus Anatomy Nasal Physiology Nasal Endoscopy Skull Base Anatomy Virtual Anatomy Disclosure ... Patient Education About this Website Font Size + - Home > ANATOMY > Nasal Physiology Nasal Anatomy Sinus Anatomy Nasal Physiology Nasal Endoscopy ...

  6. Nasal Anatomy

    Science.gov (United States)

    ... Caregivers Contact ARS HOME ANATOMY Nasal Anatomy Sinus Anatomy Nasal Physiology Nasal Endoscopy Skull Base Anatomy Virtual Anatomy Disclosure ... Size + - Home > ANATOMY > Nasal Anatomy Nasal Anatomy Sinus Anatomy Nasal Physiology Nasal Endoscopy Skull Base Anatomy Virtual Anatomy Disclosure ...

  7. FLOW-Methode - Methodenbeschreibung zur Anwendung von FLOW

    CERN Document Server

    Stapel, Kai

    2012-01-01

    Information of many kinds is flowing in software projects and organizations. Requirements have to flow from the customer to the developers. Testers need to know the requirements as well. Boundary conditions and design decisions have to be at the right place at the right time. Information flow analysis with FLOW facilitates modeling of mode and route of the flow of information and experience independent of the development methodology. Experience often acts as a control factor, because experienced developers can process and route information more efficiently. Therefore, experience needs to be at the right place at the right time, too. However, most valuable experiences never get documented. Since information and experience is flowing in agile as well as in traditional environments, the FLOW method does not distinguish between agile and traditional, but only between how the flows are shaped. ---- In Softwareprojekten flie{\\ss}en vielerlei Informationen. Anforderungen m\\"ussen vom Kunden zu den Entwicklern gelang...

  8. Anwendung von Industrie 4.0 in Forschung und Praxis

    OpenAIRE

    Meussen, Bernhard

    2015-01-01

    Auf der Hannover-Messe 2011 trat die Initiative "Industrie 4.0" an die Öffentlichkeit. Seither wird in Deutschland aktiv an diesem Thema gearbeitet. Dieses Arbeitspapier greift die anhaltende Diskussion zu dem Thema auf, stellt verschiedene Anwendungen der Industrie-4.0-Welt exemplarisch dar und versucht hieraus einen pragmatischen Ansatz für die weitere Umsetzung der Ideen hinter Industrie 4.0 zu geben.

  9. Hydrogen in motor car engineering. Production, storage, uses. 2. rev. and enl. ed.; Wasserstoff in der Fahrzeugtechnik. Erzeugung, Speicherung, Anwendung

    Energy Technology Data Exchange (ETDEWEB)

    Eichlseder, Helmut; Klell, Manfred

    2010-07-01

    The book presents a general outline of the various aspects of characteristics, generation, storage and applications of hydrogen. The focus is on the thermodynamic aspects of hydrogen storage and on its uses in automotive engineering and power engineering. The 2nd edition also contains a new chapter on fuel cells for power generation for electric motors and a chapter on hydrogen production by pyrolysis of glycerine. New information is presented on current applications, internal combustion engines fuelled with mixtures of hydrogen and methane, materials, efficiency aspects, and CO2 emissions. [German] Das Buch bietet einen allgemeinen Ueberblick ueber die verschiedenen Aspekte von Eigenschaften, Erzeugung, Speicherung und Anwendung von Wasserstoff. Schwerpunkte liegen auf der Thermodynamik der Speicherung von Wasserstoff sowie auf der Anwendung in der Fahrzeugtechnik und in der Energietechnik. Als eigener Abschnitt wurde in dieser 2. Auflage die Brennstoffzelle zur Stromerzeugung fuer Elektroantriebe ergaenzt. Ein Verfahren zur Wasserstoffproduktion durch Pyrolyse aus Glycerin wurde neu aufgenommen. Ergaenzt wurden Abschnitte ueber aktuelle Anwendungen, ueber Verbrennungsmotoren fuer Gemische aus Wasserstoff und Methan, ueber Werkstoffe sowie Fragen von Wirkungsgrad und CO{sub 2}-Emissionen.

  10. New findings for the use of NMR- and computer tomography for gauging the potential of drilling fluids to cause damage to rocks; Neue Erkenntnisse bei der Anwendung von NMR- und Computertomografie-Methoden im Rahmen der Bewertung des Traegerschaedigungspotentiales von Bohrfluessigkeiten

    Energy Technology Data Exchange (ETDEWEB)

    Zwaag, C. van der [Reservoir Labs. AS, Trondheim (Norway); Stallmach, F. [Univ. Leipzig (Germany). Fakultaet fuer Physik und Geowissenschaften; Hanssen, J.E. [MI/Anchor Drilling Fluids AS, Stavanger (Norway); Soergaard, E. [Norsk Hydro AS, Bergen (Norway); Toennesen, R. [Saga Petroleum ASA, Stavanger (Norway)

    1998-12-31

    Polyanionic cellulose, xanthane and ppolyglycole are standard additives for water-based drilling fluids. These are added to drilling liquids to control water loss, provide viscosity and inhibit slating. Filtration losses, which are unavoidable when drilling, cause scavenging polymers to penetrate the area around the drilled hole. This causes a number of different reactions with the surrounding rocks and may ultimately have a permanent influence on the flow conditions of hydrocarbons. The study mentioned above aimed at determining the damage potential of these additives. [Deutsch] Polyanionische Cellulose, Xanthan und Polyglykol sind uebliche Zusatzstoffe von wasserbasischen Bohrspuelungen. Diese werden Bohrfluessigkeiten zur Wasserverlustkontrolle, zur Viskositaetsbildung und zur Schieferinhibierung zugesetzt. Die beim Bohrprozess unvermeidlichen Filtrationsverluste fuehren dazu, dass Spuelungspolymere beim Bohren in den Bohrlochnahbereich eindringen. Die Beschaffenheit dieser Stoffe fuehrt nach dem Eindringen zu unterschiedlichen Reaktionen mit dem Traegergestein. Diese koennen letzten Endes einen dauerhaften Einfluss auf die Zuflussbedingungen von Kohlenwasserstoffen haben. Das Ziel der vorliegenden Studie war es, das Traegerschaedigungspotential der obengenannten Spuelungszusaetze zu charakterisieren. (orig.)

  11. Freezing grip - new application of the Peltier technology; Gefriergreifer - neue Anwendung der Peltier-Technik

    Energy Technology Data Exchange (ETDEWEB)

    Jensen, L.; Stephan, J. [NAISS GmbH, Berlin (Germany)

    2002-12-01

    The rising requirements in efficiency and quality lead to products of in addition integration and functionality with ever smaller components. In addition new materials with improved characteristics are used e.g. GRP components plastics. Due to the characteristics of miniature units and new materials an automated assembling process becomes ever more difficult. With CRYO grip gripping tools were developed, which transport material units and carefully. (orig.) [German] Die steigenden Anforderungen an Leistungsfaehigkeit und Qualitaet fuehren zu Produkten hoeherer Integration und Funktionalitaet mit immer kleineren Komponenten. Ausserdem kommt es zur Anwendung neuer Werkstoffe mit verbesserten Eigenschaften wie z. B. Faserverbundkunststoffen. Aufgrund der Eigenschaften von Miniaturbauteilen und neuer Materialien wird ein automatisierter Montageprozess immer schwieriger. Mit CRYO-Greifern sind Greifwerkzeuge entwickelt worden, die materialschonend und sicher solche Bauteile transportieren. (orig.)

  12. Das Umformverhalten von Magnesiumblechen der Legierungen AZ31 und ZE10

    OpenAIRE

    Stutz, Lennart

    2015-01-01

    Die Anwendung von Magnesiumblechen im Ultraleichtbau der Transportindustrie verspricht ein hohes Potential zur weiteren Gewichts- und somit Emissionsreduzierung. Die eingeschränkte Kaltumformbarkeit von verfügbaren Magnesiumblechen stellt ein Hindernis dar, welches durch legierungstechnische Maßnahmen überwunden werden kann. Die kristallographische Textur ist in vorangegangenen Arbeiten als maßgeblicher Einflussfaktor auf das Umformvermögens von Magnesiumblechen identifiziert worden. Die Zule...

  13. Untersuchung des Reinigungseffektes von Ultraschall auf Oberflächen von Chirurgie-Instrumenten und dessen prototypische Umsetzung in ein Dekontaminationsverfahren

    OpenAIRE

    Kahlen, Insa

    2012-01-01

    Viele Medizinprodukte aus der Chirurgie stellen besonders hohe Anforderungen an ihre Aufbereitung, da sie z.B. wie die so genannten „Langschaftinstrumente“ enge und sehr langgestreckte Lumen aufweisen, die zum Teil nicht einsehbar sind. Laut der Richtlinie „Anforderungen an die Hygiene bei der Aufbereitung von Medizinprodukten“ vom RKI und der BfArM soll die Aufbereitung von solchen Medizinprodukten durch Anwendung validierter Verfahren durchgeführt werden und der Erfolg stets nachvollziehbar...

  14. Idiopathic calcinosis cutis of nasal dorsum

    Directory of Open Access Journals (Sweden)

    Shrinath D.P Kamath

    2012-01-01

    Full Text Available A 23-year-old lady presented with a slowly progressing firm mass on the nasal dorsum since 8 months. Her biochemical, haematological and collagen vascular disease screening tests were normal. Radiographs of the nasal bones showed a subcutaneous calcifying lesion with no evidence of nasal bone erosion. A diagnosis of idiopathic calcinosis cutis (ICC was made. The mass was excised and soft tissue defect was augmented with silicone prosthesis. The histopathology with the haematoxylin and eosin staining and von Kossa stain confirmed the diagnosis of calcinosis cutis. This is an unusual presentation of ICC involving the nasal dorsum requiring surgery and nasal dorsal augmentation with silicone prosthesis.

  15. Herstellung, In-line-Einschluss und Charakterisierung lipophiler und hydrophiler Kamillenextrakte unter Einsatz von verdichtetem Kohlendioxid

    OpenAIRE

    Kaiser, Claudia Susanne

    2003-01-01

    In dieser Arbeit werden die Möglichkeiten der Anwendung von überkritischem CO2 im Bereich der Naturstoffextraktion anhand der Kamille als Modellpflanze untersucht. Kamillenblüten enthalten eine Vielzahl von pharmakologisch wirksamen Inhaltsstoffen mit unterschiedlichsten Eigenschaften im Hinblick auf Polarität und Stabilität und stellen damit eine ideale Matrix dar, um ein breites Spektrum an Einflussgrößen zu untersuchen. Die Optimierung der Extraktionsparameter ergibt hohe Selektivität ...

  16. Combined application of numerical simulation models and fission tracks analysis in order to determine the history of temperature, subsidence and lifting of sedimentary basins. A case study from the Ruhr Coal basin inWest Germany; Die kombinierte Anwendung numerischer Simulationsmodelle und Spaltspurenuntersuchungen zur Entschluesselung der Temperatur-, Subsidenz- und Hebungsgeschichte von Sedimentbecken - Ein Fallbeispiel aus dem Ruhrkohlenbecken Westdeutschlands

    Energy Technology Data Exchange (ETDEWEB)

    Karg, H. [Forschungszentrum Juelich (Germany). Inst. fuer Erdoel und organische Geochemie; Littke, R. [RWTH Aachen (Germany); Bueker, C. [Univ. Bern (Switzerland). Inst. fuer Geologie

    1998-12-31

    The Ruhr Coal basin is one of the globally best known sedimentary basins. According to classical, established the Ruhr Basin is a typical foreland molasse basins. The thermal history (heating and cooling) and the structural and sedimentary development since the formation of the basin, i.e. subsidence and lifting and erosion are of the first importance for the potential formation of hydrocarbons. In order to quantify these processes, two-dimensional numerical simulation models (based on geological and seismological sections) of the Ruhr basin were developed from which one could conclude the heat flow at the time of maximum basin depth after variscis orogenesis, maximum temperatures of individual strata sections and thickness of eroded strata. The PetroMod program package of the company IES/Juelich was used for these analyses. Finite-element-grids enable mathematican mapping and reconstruction of complex geological structures and processes. The models on temperature history are calibrated by comparing measured and calculated carbonification (vitrinite reflection) data. (orig./MSK). [Deutsch] Das Ruhrkohlenbecken stellt weltweit eines der am besten erforschten Sedimentbecken dar. Nach klassischen und etablierten Beckenmodellen kann das Ruhrbecken als typisches Vorlandmolassebecken angesehen werden. Besonders relevant fuer die potentielle Bildung von Kohlenwasserstoffen sind in erster Linie die thermische Geschichte (Aufheizung und Abkuehlung) sowie die strukturelle und sedimentaere Entwicklung seit der Beckenbildung, sprich Versenkungs-, Hebungs- und Erosionsprozesse. Um solche Prozesse zu quantifizieren, wurden im Ruhrbecken zweidimensionale (d.h. auf der Grundlage von geologischen und seismischen Sektionen) numerische Simulationsmodelle entwickelt, die Aufschluss ueber Waermefluesse zur Zeit der maximalen Beckeneintiefung im Anschluss an die variszische Orogenese, erreichte Maximaltemperaturen einzelner Schichtglieder sowie die Maechtigkeit erodierter Schichten im

  17. Nasal Cancer

    Science.gov (United States)

    ... the way to your throat as you breathe. Cancer of the nasal cavity and paranasal sinuses is ... be like those of infections. Doctors diagnose nasal cancer with imaging tests, lighted tube-like instruments that ...

  18. Application of C-arm computed tomography in cardiology; Kardiale Anwendung der C-Arm-Computertomographie

    Energy Technology Data Exchange (ETDEWEB)

    Rieber, J. [Klinikum der Ludwig-Maximilians-Universitaet Muenchen, Campus Innenstadt, Abteilung fuer Kardiologie, Medizinische Poliklinik, Muenchen (Germany); Rohkohl, C. [Friedrich-Alexander-Universitaet Erlangen-Nuernberg, Lehrstuhl fuer Mustererkennung, Department Informatik, Erlangen (Germany); Siemens AG, Healthcare Sector, Forchheim, Forchheim (Germany); Lauritsch, G. [Siemens AG, Healthcare Sector, Forchheim, Forchheim (Germany); Rittger, H. [Krankenhaus Coburg, Abteilung fuer Kardiologie, Coburg (Germany); Meissner, O. [Siemens AG, Healthcare Sector, Forchheim, Forchheim (Germany); Klinikum der Ludwig-Maximilians-Universitaet Muenchen, Institut fuer Klinische Radiologie, Muenchen (Germany)

    2009-09-15

    C-arm computed tomography is currently being introduced into cardiac imaging and offers the potential for three-dimensional imaging of the cardiac anatomy within the interventional environment. This detailed view is necessary to support complex interventional strategies, such as transcutaneous valve replacement, interventional therapy of atrial fibrillation, implantation of biventricular pacemakers and assessment of myocardial perfusion. Currently, the major limitation of this technology is its insufficient temporal resolution which limits the visualization of fast moving parts of the heart. (orig.) [German] Durch die Entwicklung der C-Arm-Computertomographie- (CACT-)Angiographie ist es erstmals moeglich, waehrend einer Herzkatheteruntersuchung eine detaillierte dreidimensionale Darstellung der kardialen Anatomie zu erhalten. Derartige zusaetzliche Informationen koennten die Durchfuehrung der immer komplexer werdenden Strategien der interventionellen Kardiologie wirkungsvoll unterstuetzen. Hierzu zaehlen u. a. der transkutane Klappenersatz, die interventionelle Behandlung von Vorhofflimmern, die Implantation biventrikulaerer Schrittmacher sowie die Beurteilung der Myokardperfusion. Die derzeit groesste Limitation dieser Methode ist die relativ geringe zeitliche Aufloesung, die aufgrund der Bewegung des Herzens die Anwendung dieser Technologie einschraenkt. (orig.)

  19. Biofuels - Properties and application experience; Biokraftstoffe - Eigenschaften und Erfahrungen bei der Anwendung

    Energy Technology Data Exchange (ETDEWEB)

    Schmiedel, H.P.

    2002-12-01

    The European Union wants to promote the use of renewable raw materials also in the traffic sector in order to meet the internationally committed reduction of carbon dioxide emissions. At the same time a new market shall be created for farming and jobs shall be secured. Fatty acid methyl esters in the diesel market and ethanol and ethyl tertiary butyl ether (ETBE) in gasoline are discussed as compounds that can be produced from renewable raw materials and be applied as fuels in the short term. This literature survey deals with the extent of CO{sub 2} / greenhouse gas emission reductions, the availability of biofuels and summarizes the economical and technical experiences obtained so far with their application. The use of pure vegetable oils, dimethylether and pyrolysis oil is also briefly covered. (orig.) [German] Die EU will auch im Verkehrsbereich den Einsatz nachwachsender Rohstoffe foerdern, um die international zugesagte Reduzierung der Kohlendioxid-Emissionen zu erreichen. Gleichzeitig sollen damit der Landwirtschaft ein neuer Markt eroeffnet und Arbeitsplaetze gesichert werden. Fettsaeuremethylester fuer den Dieselbereich sowie Ethanol und Ethyltertiaerbutylether (ETBE) fuer Ottokraftstoff werden als Verbindungen genannt, die aus nachwachsenden Rohstoffen gewonnen und kurzfristig als Kraftstoff eingesetzt werden koennen. Die vorliegende Literaturstudie beleuchtet den Umfang der CO{sub 2}- bzw. Klimagasreduktion, die Verfuegbarkeit der Biokraftstoffe und fasst die oekonomischen und technischen Erfahrungen zusammen, die bisher in ihrer Anwendung erhalten wurden. Die Nutzung von reinen Pflanzenoelen, Dimethylether und Pyrolyseoel wird gestreift. (orig.)

  20. Current imaging of nasal sinuses; Moderne Bildgebung der Nasennebenhoehlen

    Energy Technology Data Exchange (ETDEWEB)

    Reith, W. [Universitaetsklinikum des Saarlandes, Klinik fuer Diagnostische und Interventionelle Neuroradiologie der Kliniken fuer Radiologie, Homburg (Germany)

    2005-09-01

    gekippt werden, dass die Zahnartefakte nicht im abgebildeten Volumen liegen. Bei Wahl eines isotropen Voxels koennen sekundaere Reformatierungen ohne Qualitaetsverlust durchgefuehrt werden. Zur Diagnostik einer tumoroesen Raumforderung empfehlen sich in der Regel koronare Schichten mit einer Schichtdicke von ca. 2 mm, entweder in Spiral- oder konventioneller Technik. Die MRT-Diagnostik sollte T2- und T1-gewichtete Sequenzen vor und nach Kontrastmittelgabe enthalten. Auch eine T2-gewichtete fettunterdrueckte Sequenz, bzw. eine STIR-Sequenz kann hilfreich sein zur Differenzierung und Abbildung von Lymphknoten. Zur Beantwortung der Frage einer moeglichen Orbitabeteiligung empfiehlt sich die zusaetzliche Anwendung einer T1-gewichteten fettunterdrueckten Sequenz in koronarer Schichtorientierung. (orig.)

  1. The integrity concept and its implementation; Das Integritaetskonzept und seine praktische Anwendung

    Energy Technology Data Exchange (ETDEWEB)

    Roos, E.; Herter, K.H.; Schuler, X. [Stuttgart Univ. (Germany). MPA; Koenig, G. [EnBW Kernkraft GmbH, Neckarwestheim (Germany)

    2008-07-01

    , dass fuer die Gewaehrleistung von Bruchausschluss die Beherrschung der Ursachen von im Betrieb moeglichen Schaedigungsmechanismen von entscheidender Bedeutung ist. Im Gegensatz dazu stellt das ''Integritaetskonzept'' als Umsetzung des Basissicherheitskonzepts unter Beruecksichtigung der jeweiligen anlagenspezifischen Voraussetzungen ein geschlossenes Gesamtkonzept dar, das der Notwendigkeit einer mehrstufigen Absicherung und ''laufender'' Aktualisierung Rechnung traegt. Das Integritaetskonzept ist Bestandteil des Alterungsmanagements fuer mechanische Komponenten und Systeme. Am Beispiel der Speisewasserleitung innerhalb Containment der Anlage GKN 1 wird dessen praktische Anwendung zum Nachweis der Integritaet aufgezeigt. (orig.)

  2. Flow optimization in blowers by means of LDA measurements; Stroemungstechnische Optimierung von Ventilatoren mit Hilfe der LDA-Messtechnik

    Energy Technology Data Exchange (ETDEWEB)

    Reichert, E.; Strehle, M. [ebm Werke GmbH und Co. KG, Mulfingen (Germany); Bohl, K. [Heilbronn Fachhochschule (Germany)

    2003-06-01

    The contribution describes the application of LDA techniques for flow measurements and optimization of blowers. Three examples are presented to show how LDA measurements can be used for optimization and design of industrial blowers. [German] Der Beitrag beschreibt die Anwendung der LDA-Messtechnik fuer die stroemungstechnische Entwicklung und Optimierung von Ventilatoren. An drei Beispielen wird gezeigt, wie im industriellen Einsatz mit LDA-Messungen wesentliche Informationen ermittelt werden koennen, die dann zur Verbesserung oder zur Auslegung von Ventilatoren eingesetzt werden. (orig.)

  3. Analytik, Stabilität und Biotransformation von Spinsonden sowie deren Einsatz im Rahmen pharmazeutisch-technologischer und biopharmazeutischer Untersuchungen

    OpenAIRE

    Kroll, Christian

    1999-01-01

    Im Mittelpunkt der vorliegenden Arbeit stehen Untersuchungen zur Analytik, Stabilität und Metabolisierung von Nitroxylradikalen, unter besonderer Berücksichtigung Ihrer Anwendung als ESR-Spinsonden im Rahmen der Bearbeitung pharmazeutisch-technologischer und biopharmazeutischer Fragestellungen. Neben der Entwicklung und Adaptierung geeigneter analytischer Methoden waren dabei Stabilitätsfragen unter den Bedingungen ihres Einsatzes, die Stabilität von Reaktionsprodukten und Metaboliten, da...

  4. Nasal lifting.

    Science.gov (United States)

    Pontes, Ronaldo; Pontes, Gisela Hobson; Serpa, Narayana Pauline; Lopez, Carlos

    2005-01-01

    Patients with gland hyperplasia as well as thickening and redundancy of nasal skin who receive treatment that addresses only the support structures generally suffer from lack of definition of the nasal tip. We report on a case in which this problem was treated by redefinition of the nasal dorsum and tip through resection of the redundant skin. The surgical approach involved open rhinoplasty with a columella-alar incision, wide dissection of the dorsum filling, caudal traction, and resection of excess tissue. This method enabled reshaping of the nasal dorsum and tip by readjustment of the cutaneous covering of the osteocartilaginous structures.

  5. Laser-induced thermotherapy (LITT). Application of round and sharp laser systems; Laserinduzierte interstitielle Thermotherapie (LITT). Anwendung und spitzer Laserapplikatorsysteme - erste Ergebnisse

    Energy Technology Data Exchange (ETDEWEB)

    Puls, R.; Stroszczynski, C.; Felix, R. [Virchow Klinikum Berlin (Germany). Strahlenklinik; Humboldt-Universitaet, Berlin (Germany). Inst. fuer Roentgendiagnostik; Hosten, N. [Greifswald Univ. (Germany). Inst. fuer Diagnostische Radiologie; Kreissig, R.; Gaffke, G. [Virchow Klinikum Berlin (Germany). Strahlenklinik

    2001-03-01

    Purpose: To assess the advantages and disadvantages by using round and sharp laser application systems during laser-induced thermotherapy. Method: 6 in vitro examinations were performed and 12 patients with liver metastases of colerectal carcinoma were treated with laser-induced thermotherapy. All lesions were closely localised to the diaphragm, liver capsule and large intrahepatic vessels. Five patients were treated with the sharp and 7 patients with the round applicator system. After CT-guided insertion of the catheter system into the metastasis laser therapy was performed under MRI control (approx. 25 M, 20 min). Results: Reduction of the distance between the laser applicator and rounded laser catheter tipp (approx. 0.5-1 cm) leads to better placement of the laser applicator in metastases located near the diaphragm, liver capsule and large intrahepatic vessels. Improved therapy results due to complete ablation of metastases were obtained. All patients treated with the round system had complete ablation of metastasis. In 3 of 5 patients treated with the sharp system, MRI control 2 days after therapy showed a residual tumour margin close to the diaphragm or to an intrahepatic vessel. Discussion: Improved ablation can be obtained by closer placement of a round laser catheter in liver metastasis located near the diaphragm, liver capsule and large intrahepatic vessels. (orig.) [German] Ziel: Erarbeitung der Vorteile und Nachteile bei Anwendung von runden und spitzen Laserapplikatorsystemen im Rahmen der laserinduzierten interstitiellen Thermotherapie. Material/Methode: Neben 6 In-vitro-Versuchen wurden 12 Patienten mit Lebermetastasen kolorektaler Karzinome mit Lokalisation unter dem Zwerchfell bzw. am Leberrand oder in der Naehe von grossen Lebergefaessen mit der laserinduzierten Thermotherapie (LITT) behandelt. 5 Patienten wurden mit spitzen, 7 Patienten mit runden Laser-Applikationssets behandelt. Nach CT-gesteuerter Punktion der Metastasen erfolgte die LITT unter

  6. Schwangerschaften während der Anwendung kontrazeptiver Methoden - Eine Stellungnahme der Deutschen Gesellschaft für Gynäkologische Endokrinologie und Fortpflanzungsmedizin (DGGEF e.V. und des Berufsverbands der Frauenärzte (BVF e.V.

    Directory of Open Access Journals (Sweden)

    Rabe T

    2013-01-01

    Full Text Available Alle kontrazeptiven Methoden bei der Frau weisen keine 100%ig zuverlässige Verhütungssicherheit auf. Eine Schwangerschaft während der Anwendung kontrazeptiver Methoden tritt unvorbereitet, unerwartet und gelegentlich auch über längere Zeit unerkannt auf. Innerhalb kurzer Zeit müssen das Risiko für die Schwangerschaft und ggf. für die Schwangere abgeschätzt und mögliche weitere Schädigungen des Embryos vermieden werden. Die Beratung wird durch die unzureichende Datenlage zu Schwangerschaften während der Anwendung kontrazeptiver Maßnahmen erschwert. Der Artikel gibt zunächst eine Übersicht über grundsätzliche Aspekte zur Teratogenität von Medikamenten und beschreibt anschließend die besonderen Risiken, die mit der unbeabsichtigten Anwendung kontrazeptiver Maßnahmen in der Schwangerschaft verbunden sind. Für hormonelle kombinierte Kontrazeption (oral, vaginal, transdermal wird aktuell kein erhöhtes teratogenes Risiko bei der Anwendung in der Frühschwangerschaft angenommen. Hingegen wird für einige Gestagene bei therapeutisch hochdosierter Einnahme in der Frühschwangerschaft ein erhöhtes teratogenes Risiko diskutiert. Die Anwendung einer postkoitalen Kontrazeption mit reinen Gestagenen oder selektiven Progesteronrezeptor-Modulatoren scheint nach aktueller Datenlage nicht mit einem Risiko für den Embryo einherzugehen. Risiken für die Schwangerschaft bei liegendem Kupfer-haltigen IUP bestehen insbesondere in einer erhöhten Rate an Infektionen, Extrauteringraviditäten sowie Fehl- und Frühgeburten. Schwangerschaften unter einem korrekt liegenden Gestagen-freisetzenden Intrauterin-System sind zu selten, um eine klare Aussage zur möglichen Teratogenität des lokal wirksamen Gestagens zu treffen. Ziel dieser Übersicht ist es, neben der Beschreibung von Studien und Daten zur Wirkung von Kontrazeptiva auf eine Schwangerschaft, konkrete Vorgehensweisen, obligate Aspekte der Beratung und spezialisierte Beratungsstellen

  7. Neurotoxizität von Emodepsid in Abhängigkeit der MDR1-Expression in der Blut-Hirn-Schranke

    OpenAIRE

    2015-01-01

    Ziel dieser Arbeit war die Aufdeckung eines möglichen Zusammenhangs zwischen dem MDR1-Genotyp und dem Auftreten von Arzneimittelunverträglichkeiten nach der Anwendung von Profender® beim Hund. Solche Arzneimittelunverträglichkeiten wurden unserem Institut in den letzten Jahren im Rahmen der MDR1-Diagnostik häufig gemeldet. Durch eine retrospektive Auswertung dieser gesammelten Fälle ist es gelungen den vermuteten Zusammenhang zum MDR1-Genotyp der betroffenen Tiere aufzudecken und durch we...

  8. Einfluss der Milchpasteurisierung und der Reifungszeit auf die Bildung von Schlüsselaromastoffen in Käse nach Gouda-Art

    OpenAIRE

    Duensing, Philipp Werner

    2014-01-01

    Käse wird aus dickgelegter Milch durch Fermentation mit Hilfe von Mikroorganismen-Kulturen hergestellt. Die käsetypischen Aromastoffe entstehen im Verlauf der Reifung durch eine Vielzahl biochemischer Reaktionen. Durch Anwendung des Konzeptes der molekularen Sensorik auf einen gereiften Gouda-Käse aus pasteurisierter Milch konnten Essig-, Butter, und 3-Methylbuttersäure, gefolgt von 2,3-Butandion und delta-Decalacton als wichtigste unter den 39 Aromastoffen charakterisiert werden. Die Simulat...

  9. Nasal polyps

    Science.gov (United States)

    ... BS, Burks AW, et al, eds. Middleton's Allergy: Principles and Practice . 8th ed. Philadelphia, PA: Elsevier Saunders; 2014:chap 43. Becker SS. Surgical management of polyps in the treatment of nasal airway ...

  10. Innovationen in der druckbaren Elektronik: Von der Idee zur Produktion. Eine technische und wirtschaftliche Analyse.

    OpenAIRE

    2013-01-01

    Die druckbare Elektronik ist noch eine junge Technologie, der großes Potential vorhergesagt wird. So wird für die druckbare Elektronik mittel- bis langfristig ein globales Marktvolumen von mehreren hundert Milliarden Euro prognostiziert. Druckbare Elektronik beschreibt eine Technologie, die mit angepassten Materialien in Kombination mit adaptierten Fertigungstechnologien, neuartige Anwendung ermöglicht, die der konventionellen Elektronik bisher nicht zugänglich waren. Beispiele für diese neue...

  11. Reorganisation der IT-Prozesse auf Basis von Referenzmodellen - eine kritische Analyse

    OpenAIRE

    Walter, Sven Markus;Krcmar, Helmut

    2014-01-01

    Der Beitrag enth?lt eine kritische Analyse der Referenzmodelle f?r IT-Prozesse. Zuerst wird ein ?berblick ?ber Referenzmodelle f?r das IT Service Management gegeben. Diese ?bersicht wird durch einige Referenzmodelle erg?nzt, deren Ursprung im Bereich Softwareentwicklung liegt. Im Anschluss daran erfolgt ein systematischer Vergleich ausgew?hlter Referenzmodelle hinsichtlich der darin enthaltenen Inhalte. Auf Basis dieser Untersuchung werden Schlussfolgerungen f?r die Anwendung von Referenzmode...

  12. Gerbstoffe aus Potentilla officinalis wirken entzündungshemmend im UV-Erythem-Test und bei Anwendung auf atopischer Haut.

    Science.gov (United States)

    Hoffmann, Julia; Wölfle, Ute; Schempp, Christoph M; Casetti, Federica

    2016-09-01

    Das Rhizom von Potentilla officinalis (PO) ist reich an Gerbstoffen und wird traditionell zur äußerlichen Behandlung von Entzündungen der Haut und der Schleimhäute verwendet. Ziel der vorliegenden Arbeit war die Bestätigung der antiinflammatorischen Eigenschaften von PO mittels eines UV-Erythem-Tests und einer klinischen Anwendungsstudie bei atopischer Haut. Die antiinflammatorische Wirkung eines PO-Extrakts (standardisiert auf 2 % Trockensubstanz) wurde in einer prospektiven, randomisierten, placebokontrollierten Doppelblindstudie mit 40 gesunden Erwachsenen im UV-Erythem-Test im Vergleich zu 1 % Hydrocortisonacetat untersucht. Im Rahmen einer prospektiven nicht kontrollierten Studie wurde die Wirkung und Verträglichkeit der 2 % PO-Creme an zwölf Erwachsenen und zwölf Kindern mit atopischer Haut nach Anwendung über zwei Wochen in einem definierten Testareal anhand eines Teil-SCORAD untersucht. Zusätzlich wurde die Beeinflussung der Hautrötung im Testareal photometrisch gemessen. Im UV-Erythem-Test zeigte die PO-Creme eine signifikante Reduktion des Erythemindex im Vergleich zum Vehikel. Die antiinflammatorische Wirkung des Verums entsprach der der 1 % Hydrocortisonacetat-Creme. Die klinische Studie bei Atopikern zeigte eine signifikante Abnahme des Teil-SCORAD und des Erythems im Testareal. Es wurden keine Unverträglichkeitsreaktionen beobachtet. PO als 2%ige Zubereitung besitzt entzündungshemmende Eigenschaften und ist wirksam und gut verträglich auf atopischer Haut. © 2016 Deutsche Dermatologische Gesellschaft (DDG). Published by John Wiley & Sons Ltd.

  13. Die Durchführung von Unionsrecht durch die Verwaltung eines föderal organisierten Mitgliedstaats

    Directory of Open Access Journals (Sweden)

    Stefan Börger

    2015-04-01

    Full Text Available Eine föderale Struktur erleichtert die Durchführung von Unionsrecht nicht. In Österreich hat sich jedoch nach 20 Jahren EU-Mitgliedschaft eine zweckmäßige Struktur etabliert, um mit den Herausforderungen in der Umsetzung und Anwendung von Unionsrecht im Bundesstaat umgehen zu können. Der Beitrag bespricht anhand aktueller Themen und Beispiele typische Fragen im Verhältnis EU-Mitgliedstaat-Bundesland wie die Umsetzungszuständigkeit von Richtlinien, den Umgang mit Vertragsverletzungsverfahren und Bußgeldverfahren oder die Frage unionsrechtlich begründeter subjektiver Rechte.

  14. Anwendung von CFD-Programmen für brandtechnische Berechnungen

    DEFF Research Database (Denmark)

    Carlsson, Jörgen; Husted, Bjarne; Göransson, Ulf;

    2006-01-01

    , in the worst case, may give erroneous results and that the calculation times are too long to be useful in practical fire safety engineering. This article takes a practical view on the use of CFD programmes for fire simulation by looking at two widely used models, SOFIE and FDS.......Computational Fluid Dynamics (CFD) programmes have found widespread use in the combustion and fire science community. These programmes make it possible to take into account phenomena that earlier models could not describe; a typical example being the movement of the smoke in a room. Furthermore...

  15. Application of soil data on adaptation of climate; Anwendung von Bodendaten bei der Klimaanpassung

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2010-05-15

    Within the workshop of the Federal Environment Agency (Dessau-Rosslau, Federal Republic of Germany) at 20th to 30th September, 2009 in Dessau (Federal Republic of Germany), the following lectures were held: (1) Action plan adaptation - Adaptation measures and their verifiability on the basis of soil data (K. Mattern); (2) Legal background of the provision of metadata (H. Ginzky); (3) Which soil data are necessary? Requirements of Evaluation of the impact of climatic change and adaptation (W. Eckelmann); (4) Which soil data are present? Chances, deficits and recommendations for action (C. Kaufmann); (5) Instruments for providing metadata (W. Kappler); (6) Project TERENO - Soil atmosphere interactions induced by land use changes as a result of global change (H. Bogena, T. Puetz, H. Vereecken); (7) Further development and implementation of an European forest monitoring sysem (O. Granke); (8) Survey of the state of soil in agriculture and forestry (S. Schobel, C. Siebner); (9) Requirements on soil data from the view of the European Community (L. Montanarella); (10) Resume, view into the future, experiences with the market (F. Makeschin, H.G. Meiners, J. Mathews).

  16. Anwendung eines Radioisotop-EDX-Systems bei der Analyse von Manganknollen

    DEFF Research Database (Denmark)

    Kunzendorf, Helmar; Friedrich, G.; Plüger, W.

    1974-01-01

    Method described in the paper was used on board a research ship for determination of Mn, Fe, Co, Ni, Cu, and Zn in manganese nodules. Besides the quantitative analysis of finely ground nodules, the semi-quantitative analysis of smooth surfaces and the distribution of the elements in the nodules w...

  17. Developments in fuel cell systems for automotive application; Entwicklungstendenzen von Brennstoffzellensystemen fuer die Anwendung im Automobil

    Energy Technology Data Exchange (ETDEWEB)

    Treffinger, P.; Thalau, O. [DLR Deutsches Zentrum fuer Luft- und Raumfahrt e.V., Stuttgart (Germany). Inst. fuer Fahrzeugkonzepte; Friedrich, K.A. [DLR Deutsches Zentrum fuer Luft- und Raumfahrt e.V., Stuttgart (Germany). Inst. fuer Technische Thermodynamik

    2008-07-01

    In recent years, fuel cell systems for passenger cars have reached a high technological level leading to attractive vehicle concepts. It is expected that the future progress regarding power density increase will be slower. However, there are still a number of open questions, e.g. if the combination of cost targets and requested life time will be achieved. Also there is no final evidence, whether the actual operating parameters will meet customer's requirements. A progress in fundamental technology, e.g. improved electrolyte membranes, would be very beneficial for commercialisation. (orig.)

  18. Application of soil data in climate research; Anwendung von Bodendaten in der Klimaforschung

    Energy Technology Data Exchange (ETDEWEB)

    Kaufmann-Boll, Carolin; Kappler, Wolfgang; Lazar, Silvia [ahu AG Wasser - Boden - Geomatik, Aachen (DE)] (and others)

    2011-10-15

    The German Strategy for Adaptation to Climate Change was adopted in 2008. The implementation of the strategy requires reliable data and time series on the long-term changes in soil condition and soil functions. Soil monitoring and soil survey are essential data bases for this purpose. In Germany there are permanently established monitoring programmes with representative locations and repeated soil surveys based on a regular grid of sites. The different programmes vary in respect to harmonization regarding agreed principles between the participating institutions. Information on soil measuring data is currently heterogeneous and distributed at many locations. Particularly the provision of (meta-)data should be improved. Here you can find the exceptional quality of BOKLIM. It evaluates the suitability of soil data for climate research across the different measuring programmes in Germany. The most important nation-wide and permanently operating programmes of soil monitoring and soil survey were taken into account. The main aspects were the changes in soil condition due to climate change. As a result, the programmes provide a variety of valuable data to assess the effects of climate change on soils. Depending on the problem and the resulting requirements, the data are suitable (1) for the long-term monitoring of changes in soil condition, (2) for detailed process studies and measurements at representative locations, e.g. for the calibration and validation of predictive models, and (3) for use in model scenarios predicting changes in soil condition. However, it is necessary to coordinate the programmes of soil monitoring and soil survey with the focus on precise questions. The programmes have to be optimized at certain points to improve for issues of climate change and adaptation. In addition to the evaluation of soil data, a first concept for an efficient data provision and data use was created. Recommendations for next steps to coordinate and optimize future monitoring and survey activities and for data provision are advised to the relevant competent institutions and actors. Further research needs were identified. The recommendations aim at improving the interaction between climate change and soil conditions. They can also be taken up for other research fields such as soil protection aspects or biodiversity strategy aspects. (orig.)

  19. Functionalization of microstructure surfaces; Funktionalisierung der Oberflaeche von Mikrostrukturen - Technologie und Anwendung

    Energy Technology Data Exchange (ETDEWEB)

    Reinecke, H. [Albert-Ludwigs-Univ., Freiburg (DE). Institut Mikrosystemtechnik (IMTEK). Prozesstechnologie; Lippold, O. [Boehringer Ingelheim microParts GmbH, Dortmund (Germany). Plasmachemische Modifizierung von mikrostrukturierten Biochips; Ohl, A.; Besch, W.; Schroeder, C. [Institut fuer Niedertemperatur-Plasmaphysik e.V., Greifswald (Germany); Goetz, F. [Fachhochschule Gelsenkirchen (Germany). Mikrosystemtechnik

    2005-07-01

    Microtechnology enables the dimensioning and fabrication of cost-effective noval platforms for bio diagnostics. By the employment of plasma technologies for specific adjustment of surface characteristics, custom-designed platforms are feasible. For a fast and reliable adjustment of product properties, special test chips have been developed. The conclusions for this development and first products are presented in this article. (orig.)

  20. Anwendung der Platinspeziation zum Nachweis einer Aktivierung oder Inhibierung von Pt enthaltenden Krebsmedikamenten

    Directory of Open Access Journals (Sweden)

    Bernhard Michalke

    2014-03-01

    Der Abschnitt „Untersuchungen im Urin behandelter Krebspatienten” befasst sich mit Speziationsexperimenten an denjenigen Metaboliten der Pt-Komplexe, die vom Organismus ausgeschieden werden. Auf diese Weise könnte sich eine Beurteilung des in-vivo-Metabolismus Pt-haltiger Medikamente durchführen lassen. Schließlich werden im letzten Abschnitt des Artikels analytische Techniken beschrieben, die für die Entwicklung neuer metallhaltiger Krebsmedikamente erforderlich sind.

  1. Entkopplung von Wissenschaft und Anwendung. Eine neo-institutionalistische Analyse der unternehmerischen Universität

    OpenAIRE

    Baumeler, Carmen

    2009-01-01

    Gegenwärtig wird zunehmend das Leitbild der unternehmerischen Universität propagiert. Neben den traditionellen Zielen der Lehre und Forschung sollen Hochschulen verstärkt als ökonomische Akteure auftreten. Im universitären Kontext wird Unternehmertum u.a. als die Einnahme einer Perspektive im Forschungsalltag definiert, die wissenschaftliche Resultate in Bezug auf ihr kommerzielles Potenzial beurteilt. Der Beitrag stellt sich die Frage, wie Wissenschafts- und Technikentwicklung in der unterne...

  2. From clay bricks to deep underground storage; vom lehmziegel bis zum tiefenlager -- anwendung von ton

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2012-05-15

    This booklet issued by the Swiss National Cooperative for the Disposal of Radioactive Waste NAGRA takes a look at the use of clay strata for the storage of radioactive wastes in deep-lying repositories. First of all, a geological foray is made concerning the history of the use of clay and its multifarious uses. The characteristics of clay and its composition are examined and its formation in the geological past is explained. In particular Opalinus clay is looked at and the structures to be found are discussed. The clay's various properties and industrial uses are examined and its sealing properties are examined. Also, Bentonite clay is mentioned and work done by Nagra and co-researchers is noted.

  3. Licence to Mine? Ein Überblick über Rahmenbedingungen von Text and Data Mining und den aktuellen Stand der Diskussion.

    OpenAIRE

    Christian Winterhalter

    2016-01-01

    Der Artikel gibt einen Überblick über die Möglichkeiten der Anwendung von Text and Data Mining (TDM) und ähnlichen Verfahren auf der Grundlage bestehender Regelungen in Lizenzverträgen zu kostenpflichtigen elektronischen Ressourcen, die Debatte über zusätzliche Lizenzen für TDM am Beispiel von Elseviers TDM Policy und den Stand der Diskussion über die Einführung von Schrankenregelungen im Urheberrecht für TDM zu nichtkommerziellen wissenschaftlichen Zwecken. The article gives a survey abou...

  4. Anwendung und Verständnis der Nährwertkennzeichnung

    DEFF Research Database (Denmark)

    Grunert, Klaus G.; Fernández-Celémin, Laura; Wills, Josephine M.;

    2010-01-01

    Kann Nährwertkennzeichnung tatsächlich das Verbraucherverhalten in eine gesündere Richtung lenken? Ergebnisse einer von EUFIC durchgeführten Studie deuten darauf hin, dass viele Verbraucher existierende Nährwertkennzeichnungssysteme zwar verstehen und richtig anwenden können, aber nicht motiviert...

  5. Blutpräparate und therapeutische Anwendung (Hämotherapie)

    Science.gov (United States)

    Burkhart, Jürgen; Leimbach, Rainer; Nagl, Detlev; Weinauer, Franz

    Die Geschichte der Blutübertragung lässt sich bis in das Altertum verfolgen - wenn auch hier das Blut nicht in die Blutgefäße eingebracht, sondern als Trank verabreicht wurde. Im alten Rom stürmten die Zuschauer in die Kampfarena, um das Blut verletzter Gladiatoren zu trinken, in dem Gedanken, deren Stärke würde in sie überfließen. So wurden auch Greise mit dem Blut von Jünglingen behandelt. Der Glaube, mit dem Blut würden Eigenschaften des Spenders übertragen, muss wohl auch bei dem Versuch mitgewirkt haben, Verbrecher durch Übertragung von Schafsblut "lammfromm“ zu machen. Zu Beginn der Mensch-zu-Mensch-Übertragung wurde Blut mittels eines Röhrchens von Blutgefäß zu Blutgefäß transfundiert. Diese im Mittelalter neu erprobte Form basierte auf der Entdeckung des Blutkreislaufes durch William Harvey (1578-1657). Es überwog allerdings noch die Blutübertragung vom Tier auf den Menschen, die nicht selten mit dem Tod beider Beteiligter endete. In der aufklärerischen Phase der französischen Revolution wurde diese Art der Blutübertragung deshalb verboten.

  6. Kostenorientiertes Controlling von E-Learning-Plattformen mit dem TCO-Konzept - Methodische Grundlagen, Softwareunterstützung und Entwicklungsperspektiven

    Directory of Open Access Journals (Sweden)

    Jan vom Brocke

    2007-07-01

    Full Text Available Zur administrativen Unterstützung von Lehr- und Lernprozessen werden E-Learning-Plattformen eingesetzt, die auf der Grundlage des Internet Funktionen zur Distribution von Lehr- und Lernmaterialien und zur Kommunikation zwischen Lehrenden und Lernenden anbieten. Zahlreiche wissenschaftliche Beiträge und Marktstudien beschäftigen sich mit der multikriteriellen Evaluation dieser Softwareprodukte zur informatorischen Fundierung strategischer Investitionsentscheidungen. Demgegenüber werden Instrumente zum kostenorientierten Controlling von E-Learning-Plattformen allenfalls marginal thematisiert. Dieser Beitrag greift daher das Konzept der Total Cost of Ownership (TCO auf, das einen methodischen Ansatzpunkt zur Schaffung von Kostentransparenz von E-Learning-Plattformen bildet. Aufbauend auf den konzeptionellen Grundlagen werden Problembereiche und Anwendungspotenziale für das kostenorientierte Controlling von LMS identifiziert. Zur softwaregestützten Konstruktion und Analyse von TCO-Modellen wird das Open Source-Werkzeug TCO-Tool eingeführt und seine Anwendung anhand eines synthetischen Fallbeispiels erörtert. Abschließend erfolgt die Identifikation weiterführender Entwicklungsperspektiven des TCO-Konzepts im Kontext des E-Learning. Die dargestellte Thematik ist nicht nur von theoretischem Interesse, sondern adressiert auch den steigenden Bedarf von Akteuren aus der Bildungspraxis nach Instrumenten zur informatorischen Fundierung von Investitions- und Desinvestitionsentscheidungen im Umfeld des E-Learning.

  7. Mikromorphologische und archäopedologische Untersuchungen von Böden und Sedimenten der bronzezeitlichen Siedlung Tell Chuera, Nord-Syrien

    OpenAIRE

    Fritzsch, Dagmar

    2011-01-01

    Im Vordergrund dieser Dissertation steht die Methode der Mikromorphologie, die verknüpft mit weiteren bodenkundlichen Analysen sowohl bodenkundliche Fragen, als auch siedlungsfunktionale Fragen beantworten kann. Die Methode dient also ideal der Verknüpfung von Bodenkunde und Archäologie. Der Begriff Archäopedologie beschreibt genau diese Verknüpfung – die Anwendung bodenkundlicher Methoden zur Bearbeitung archäologischer Fragestellungen. Inhalt des ersten Themenschwerpunktes dieser Arbeit ist...

  8. Nasal chondromesenchymal hamartoma with no nasal symptoms.

    LENUS (Irish Health Repository)

    Uzomefuna, Vincent

    2012-01-01

    The authors present a case of nasal chondromesenchymal hamartoma (NCMH) in an 8-year-old boy with a 4-month history of frontal headache and no symptoms of nasal obstruction, rhinorrhoea or postnasal drip. An ENT examination as well as ophthalmology assessment presented normal results. CT scan showed a lesion involving the sphenoid and ethmoid sinuses. The patient had an endoscopic resection of the lesion that was confirmed histologically to be a NCMH. Though NCMH is known to present usually in infants with obstructing nasal mass, an unusual presentation of a patient with throbbing headache without any nasal symptoms is reported here.

  9. Nasal mucosal biopsy

    Science.gov (United States)

    Biopsy - nasal mucosa; Nose biopsy ... to fast for a few hours before the biopsy. ... Nasal mucosal biopsy is usually done when abnormal tissue is seen during examination of the nose. It may also be done ...

  10. Testosterone Nasal Gel

    Science.gov (United States)

    Testosterone nasal gel is used to treat symptoms of low testosterone in men who have hypogonadism (a condition in which the ... does not produce enough natural testosterone). Testosterone nasal gel is used only for men with low testosterone ...

  11. Experience with a distributed control system toolkit in a batch application; Erfahrungen mit einem Prozessleitsystem Toolkit in einer Batch-Anwendung

    Energy Technology Data Exchange (ETDEWEB)

    Eisenbach, B. [Bayer AG, Leverkusen (Germany); Hennecke, H. [Lang und Peitler Automation GmbH, Leverkusen (Germany)

    1999-07-01

    At Bayer AG structured automation solutions have been implemented for years on Simatic S5 systems using a software specially developed for this purpose. Due to the benefits gained during implementation and especially during commissioning as well as due to the uniform documentation, this structure was transferred to the new Siemens distributed control system PCS7 in form of the Bayer S7 ToolKit. The S7 ToolKit has been applied successfully in various projects. The following article describes the application of the Bayer S7 ToolKit with regard to basic functions and batch applications. (orig.) [German] Bei der Bayer AG wird seit Jahren eine strukturierte Automatisierung bei Simatic S5-Projekten mit einem eigens dafuer entwickelten Softwaresystem realisiert. Durch die positiven Erfahrungen sowohl in der Projektierung, der vereinfachten Inbetriebnahme und der einheitlichen Dokumentation wurde diese Struktur auch auf das neue Siemens-Prozessleitsystem PCS7 in Form des S7 ToolKits uebetragen. In einer Reihe von Projekten wurde das Bayer S7 ToolKit schon angewendet. Im folgenden wird ueber den Einsatz des ToolKits in Verbindung mit Grundfunktions-Fahrweisen und einer Batch-Anwendung berichtet. (orig.)

  12. von Neumann Morgenstern Preferences

    DEFF Research Database (Denmark)

    Vind, Karl

    von Neumann Morgenstern utility is generalized to von Neumann Morgenstern preferences. The proof is an application of simple hyperplane theorems......von Neumann Morgenstern utility is generalized to von Neumann Morgenstern preferences. The proof is an application of simple hyperplane theorems...

  13. von Neumann Morgenstern Preferences

    DEFF Research Database (Denmark)

    Vind, Karl

    2000-01-01

    von Neumann Morgenstern utility is generalized to von Neumann Morgenstern preferences. The proof is an application of simple hyperplane theorems......von Neumann Morgenstern utility is generalized to von Neumann Morgenstern preferences. The proof is an application of simple hyperplane theorems...

  14. Simulation, evaluation and optimization of hydrological storage systems; Simulation, Bewertung und Optimierung von Betriebsregeln fuer wasserwirtschaftliche Speichersysteme

    Energy Technology Data Exchange (ETDEWEB)

    Lohr, H.

    2001-07-01

    The investigation focused on controlled hydrological storage system. Existing operating schedules and new control options were analyzed, classified and generalized in order to obtain a standardized terminology and operating concept. This generalized approach will do away with the need for system-specific analyses and models for every single new system. [German] Der Schwerpunkt dieser Arbeit ist der wasserwirtschaftliche Betrieb von regelbaren Speichersystemen und ihre Simulation. Dabei bestand das Ziel darin, bestehende Betriebsplaene und neue praktikable Steuerungsmoeglichkeiten zu analysieren, zu klassifizieren und so zu generalisieren, dass eine einheitliche Terminologie und Konzeption zum Betrieb von Speichern entstand. Dieses Konzept erlaubt, in Verbindung mit den Prinzipien aus der Modellierung von Flussgebieten, verschieden strukturierte Speichersysteme mit unterschiedlichsten Steuerungsvorschriften abzubilden. Damit erhaelt man den Vorteil einer generalisierten Anwendung im Gegensatz zu einer fuer den speziellen Fall konzipierten und nicht uebertragbaren Einzelloesung. Als Folge davon entfaellt das systemspezifische, je nach Aufgabenstellung neu zu entwerfende und zu programmierende Einzelmodell. (orig.)

  15. Determination of the deposition of polycyclic aromatic hydrocarbons (PAHs) to soil at Scheyern and Kirchheim near Munich; Bestimmung der Eintraege von polyzyklischen aromatischen Kohlenwasserstoffen (PAHs) an den Standorten Scheyern und Kirchheim bei Muenchen

    Energy Technology Data Exchange (ETDEWEB)

    Krainz, A.; Wiedenmann, M.; Maguhn, J. [GSF-Forschungszentrum fuer Umwelt und Gesundheit Neuherberg (Germany). Inst. fuer Oekologische Chemie

    1997-12-31

    Task force 1, ``Analysis of the exposure of soils``, carried out comprehensive and site-specific measurements of the transfer of environmental chemicals into soil by means of the example of s-triazines and polycyclic aromatic hydrocarbons (PAHs). This work was in four parts: a: Determination of PAH nuisance concentrations in selected sites (Juelich, Scheyern, Bad Lauchstaedt); b: Measurement of wet deposition, development and use of methods for the determination of dry deposition; c: Statements regarding large-area PAH transfer into soil in Germany; d: Modelling of the rates of dry deposition. (orig.) [Deutsch] Aufgabe der Arbeitsgruppe 1 `Belastungsanalyse von Boeden`: Flaechendeckende sowie standortbezogene Erfassung der Eintraege von Umweltchemikalien am Beispiel der s-Triazine und PAHs. a: Bestimmung der Immissionskonzentrationen von PAHs an den Schwerpunktstandorten (Juelich, Scheyern, Bad Lauchstaedt) b: Messung der Nassen Deposition, Entwicklung und Anwendung von Methoden zur Bestimmung der Trockenen Deposition c: Aussagen ueber flaechendeckende Eintraege von PAHs in der Bundesrepublik d: Modellierung der Trockendepositionsraten. (orig.)

  16. MR implant labelling and its use in clinical MRI practice; MR-Implantatkennzeichnungen und ihre Anwendung in der klinischen MRT-Praxis

    Energy Technology Data Exchange (ETDEWEB)

    Muehlenweg, M. [Krankenhaus Martha-Maria Halle-Doelau, Institut fuer Radiologie, Halle (Saale) (Germany); Schaefers, G. [MR:comp GmbH, Gelsenkirchen (Germany)

    2015-08-15

    Messungen von Patienten mit Implantaten. In juengerer Vergangenheit ist jedoch ein Weg geschaffen worden, diese Kontraindikation legal zu umgehen. Hierfuer sind spezielle Voraussetzungen noetig: Eindeutige Implantatidentifikation und Vorlage der originalen Herstellerkennzeichnung, Gewaehrleistung der geforderten Bedingungen bei ''bedingt MR-sicheren'' Implantaten und Restrisiko-Nutzen-Analyse mit entsprechender Aufklaerung. Dieser Prozess ist u. U. sehr aufwendig, da die Implantate haeufig schlecht dokumentiert und die Detailinformationen der Implantatkennzeichnung ebenfalls nicht selten veraltet oder nicht einfach zu interpretieren sind. Diese Arbeit informiert ueber rechtliche und normative Grundlagen der Messung von Patienten mit Implantaten. Es werden kurz moegliche physikalische Wechselwirkungen mit Implantaten angerissen, moegliche Strategien zur besseren Identifikation und Recherche von Implantaten und ihrer MR-Kennzeichnung aufgezeigt und allgemeine Ansaetze zur Risikominimierung an Beispielen diskutiert. Der zweite Teil geht auf die Inhalte von MR-Implantatkennzeichnungen ein und zeigt die aktuellen Pruefstandards auf. Es werden die fuer die Interpretation von MR-Implantatkennzeichnungen notwendigen Zusatzinformationen aus den Betriebsanleitungen der MR-Scanner erlaeutert. Abschliessend folgen die Erklaerung der aktuellen Muster-MR-Kennzeichnung von Implantaten der FDA (US Food and Drug Administration) und eine exemplarische Anwendung. (orig.)

  17. Findings relating to the use of ACPI in Windows servers; Erfahrungen in der Anwendung von ACPI bei Windows-Servern

    Energy Technology Data Exchange (ETDEWEB)

    Huser, A.; Grieder, T.

    2004-07-01

    In a practical test, the possibilities and limits of the use of energy-saving sleep modes were compiled for servers of the lower price segment. Many of these servers are used by small to medium-sized enterprises and are left running around the clock, although they are not used at night or during the week-end. The implementation of the sleep modes is based on the so-called ACPI specification (Advanced Configuration and Power Interface), which was created by an industrial consortium. The most advanced of these is the implementation for the Windows Server 2003 operating system. With Linux, the sleep modes are not yet fully available. The test was therefore carried out with the Windows Server 2003 operating system. In many applications, and in particular when the servers are used as file or web servers, no operational disadvantages result from the use of the rest states. By making use of the lowest possible sleep mode during the night and at week-ends, the energy consumption of the server can be halved. For users, the results have been summarised in a two-page fact sheet, which is enclosed with this report as an appendix. (author)

  18. Charakterisierung und Optimierung der Grenzflächenstabilisierung von Wasser-in-Öl-Emulsionen mit Ethylcellulose als Polymeremulgator

    OpenAIRE

    Maurath, Stephan

    2007-01-01

    Die (Lager-)Stabilität ausschließlich mit Ethylcellulose (EC) stabilisierter, gießfähiger W/O-Emulsionen mit Octyldodecanol als Ölphase ist für eine praktische Anwendung nicht ausreichend. Ziel der vorliegenden Arbeit ist – aufbauend auf eine systematische Charakterisierung – eine Optimierung der Grenzflächenstabilisierung ausschließlich mit Ethylcellulose stabilisierter, gießfähiger W/O-Emulsionen. Mit Hilfe von Messungen der dynamischen Grenzflächenspannungen und Grenzflächen-rheologie (...

  19. Nasal dermoid sinus cyst.

    Science.gov (United States)

    Cauchois, R; Laccourreye, O; Bremond, D; Testud, R; Küffer, R; Monteil, J P

    1994-08-01

    Nasal dermoid sinus cyst is one of the diagnoses of midline nasal masses in children. This retrospective study analyzes the various theories regarding the origin of this congenital abnormality, the differential diagnosis, and the value of magnetic resonance imaging, as well as the various surgical options available.

  20. Production parameters of sand-lime bricks with a view to reduction of heat gaps in walls. Final report; Herstellparameter von Kalksand-Spezialbaustoffen fuer die Abschwaechung von Waermebruecken im Mauerwerksbau. Abschlussbericht

    Energy Technology Data Exchange (ETDEWEB)

    Eden, W. [Forschungsvereinigung ' Kalk-Sand' e.V., Hannover (Germany); Buhl, J.C. [Hannover Univ. (Germany). Inst. fuer Mineralogie

    2002-02-01

    Sand-lime bricks with special characteristics can reduce heat gaps in walls, thus reducing the heating energy consumption of a building. Special physical characteristics are required for this, i.e. high compressive strength and low thermal conductivity. The report describes the interdependences between raw material characteristics, production processes and the properties of the resulting sand-lime bricks. [German] Im Rahmen des energiesparenden Waermeschutzes gewinnen konstruktive Massnahmen zur Reduzierung von Waermeverlusten zunehmend an Bedeutung. Beispielsweise kann bei der Anwendung von Kalksandstein-Mauerwerk durch den gezielten Einsatz von speziell entwickelten Kalksand-Leichtsteinen ein erhoehter Waermestrom ueber Waermebruecken verringert werden. Auf diese Weise kann ein weiterer Beitrag zur Reduzierung des Heizenergiebedarfs geleistet werden. Mauersteine, die zur Abschwaechung von Waermebruecken verwendet werden, muessen besondere Anforderungen hinsichtlich ihrer physikalischen Eigenschaften erfuellen. So ist die Kombination aus einer ausreichend hohen Steindruckfestigkeit und einer gleichzeitig niedrigen Waermeleitfaehigkeit entscheidend. Die vorliegende Arbeit befasst sich mit den Zusammenhaengen zwischen den Rohstoffeigenschaften, den verfahrenstechnischen Herstellbedingungen und den Eigenschaftswerten von Kalksand-Leichtsteinen fuer die Abschwaechung von Waermebruecken. (orig.)

  1. A Rare Nasal Bone Fracture: Anterior Nasal Spine Fracture

    Directory of Open Access Journals (Sweden)

    Egemen Kucuk

    2014-04-01

    Full Text Available Anterior nasal spine fractures are a quite rare type of nasal bone fractures. Associated cervical spine injuries are more dangerous than the nasal bone fracture. A case of the anterior nasal spine fracture, in a 18-year-old male was presented. Fracture of the anterior nasal spine, should be considered in the differential diagnosis of the midface injuries and also accompanying cervical spine injury should not be ignored.

  2. Friction welding of titanium to 304L stainless steel using interlayers; Reibschweissen von Titan an nichtrostendem Stahl 304L unter Anwendung von Zwischenschichten

    Energy Technology Data Exchange (ETDEWEB)

    Ashfaq, Mohammad [King Saud Univ., Riyadh (Saudi Arabia). FARCAMT, Dept. of Industrial Engineering; Prasad Rao K.; Khalid Rafi H.; Murty, B.S. [Indian Institute of Technology Madras (IITM), Chennai (India). Dept. of Metallurgical and Materials Engineering; Dey, H.C.; Bhaduri, A.K. [Indira Gandhi Centre for Atomic Research, Kalpakkam (India). Materials Technology Div.

    2011-04-15

    Friction welding of commercially pure titanium to austenitic stainless steel (AISI 304L SS) using intermediate layers was studied. The interlayers used were commercially pure nickel, tantalum and vanadium in the form of thin foils. The interlayers were aimed at avoiding direct contact between the base materials which may otherwise lead to formation of mainly Ti-Fe intermetallic phases at the interface which may seriously affect the weld properties. Interlayer foils were used individually and in combination (nickel-tantalum and nickelvanadium) suitably called in the present work as single and double interlayer joint systems respectively. Same interlayer behaved differently with respect to extrudability in these two systems. All the joints showed moderate strengths in tensile test. However, joints with single interlayer exhibited poor bend ductility, and double interlayers improved it to about 40 . Microhardness studies revealed a peak in nickel single interlayer system alone, confirming presence of hard phases at the interface. (orig.)

  3. Bacterial Nasal Infections

    Science.gov (United States)

    ... vestibule. Nasal furuncles may develop into a spreading infection under the skin (cellulitis) at the tip of the nose. A doctor becomes concerned about infections in this part of the face because veins ...

  4. Zolmitriptan Nasal Spray

    Science.gov (United States)

    ... a copy of the manufacturer's information for the patient.To use the nasal spray, follow these steps: ... used to treat certain types of migraine headaches (hemiplegic or basilar) or other types of headaches (such ...

  5. Nasal packing and stenting

    Directory of Open Access Journals (Sweden)

    Weber, Rainer K.

    2009-01-01

    Full Text Available Nasal packs are indispensable in ENT practice. This study reviews current indications, effectiveness and risks of nasal packs and stents. In endoscopic surgery, nasal packs should always have smooth surfaces to minimize mucosal damage, improve wound healing and increase patient comfort. Functional endoscopic endonasal sinus surgery allows the use of modern nasal packs, since pressure is no longer required. So called hemostatic/resorbable materials are a first step in this direction. However, they may lead to adhesions and foreign body reactions in mucosal membranes. Simple occlusion is an effective method for creating a moist milieu for improved wound healing and avoiding dryness. Stenting of the frontal sinus is recommended if surgery fails to produce a wide, physiologically shaped drainage path that is sufficiently covered by intact tissue.

  6. Budesonide Nasal Spray

    Science.gov (United States)

    ... ingredients in budesonide nasal spray. Check the package label for a list of the ingredients.tell your doctor and pharmacist what prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking or ...

  7. Fluticasone Nasal Spray

    Science.gov (United States)

    ... ingredients in fluticasone nasal spray. Check the package label for a list of the ingredients.tell your doctor and pharmacist what prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking, or ...

  8. Nasal gouty tophus: Report a rare case presenting as a nasal hump with nasal obstruction

    Directory of Open Access Journals (Sweden)

    John Chung-Han Wu

    2016-08-01

    Full Text Available Dorsal nasal gouty tophus are rare occurrences with limited documentation. Here we report a male patient who has a history of poorly controlled gouty arthritis. He had nasal obstruction with an enlarging mass over his left nasal ridge for the past three years. Image studies revealed a nasal bone defect underneath the nasal lesion. The firm mass was excised and confirmed to be of gouty origin. The nasal bone defect was repaired with a titanium mesh plate to prevent nasal depression. He has fully recovered with no more nasal obstruction or recurrence of nasal tophus. The case report illustrates a common illness, gout, with a rare clinical manifestation leading to a common symptom, nasal obstruction. It demonstrates the importance of a detailed history, a thorough physical examination and most important of all, an extensive differential diagnosis in our clinical practice.

  9. Pathophysiology of nasal congestion

    Directory of Open Access Journals (Sweden)

    Robert M Naclerio

    2010-02-01

    Full Text Available Robert M Naclerio1, Claus Bachert2, James N Baraniuk31University of Chicago, Department of Surgery, Section of Otolaryngology – Head and Neck Surgery, Chicago, Illinois, USA; 2University of Ghent, Ghent, Belgium; 3Georgetown University, Washington, DC, USAAbstract: Nasal congestion is a common symptom in rhinitis (both allergic and nonallergic, rhinosinusitis and nasal polyposis. Congestion can also be caused by physical obstruction of nasal passages and/or modulation of sensory perception. Mucosal inflammation underlies many of the specific and interrelated factors that contribute to nasal congestion, as well as other symptoms of both allergic rhinitis and rhinosinusitis. A wide range of biologically active agents (eg, histamine, tumor necrosis factor-α, interleukins, cell adhesion molecules and cell types contribute to inflammation, which can manifest as venous engorgement, increased nasal secretions and tissue swelling/edema, ultimately leading to impaired airflow and the sensation of nasal congestion. Inflammation-induced changes in the properties of sensory afferents (eg, expression of peptides and receptors that innervate the nose can also contribute to altered sensory perception, which may result in a subjective feeling of congestion. Increased understanding of the mechanisms underlying inflammation can facilitate improved treatment selection and the development of new therapies for congestion.Keywords: allergic rhinitis, congestion, obstruction, pathophysiology, rhinosinusitis

  10. Contactless measurement of phase and concentration distributions in bubble columns using positron emitting radionuclides; Beruehrungslose Messung von Phasen- und Konzentrationsverteilungen in Blasensaeulen mit positronenemittierenden Radionukliden

    Energy Technology Data Exchange (ETDEWEB)

    Zippe, C.; Hoppe, D.; Fietz, J.; Hampel, U.; Hensel, F.; Maeding, P.; Prasser, H.M.; Zippe, W.

    2003-09-01

    Positron emission tomography (PET) is a well-established method for studying metabolic processes in humans and in use as a medical diagnostic procedure (metabolism, blood perfusion, metastasis detection). The present project was dedicated to a nonmedical application of this imaging method, namely to the development and use of a PET tomograph for studying the behaviour of foam in bubble columns on the ''SchaumPET'' test stand. This paper deals in particular with the technical realisation of the project and the image acquisition methods used. The capacity of positron emission tomography to detect the accumulation of a surfactant in a foam layer is demonstrated for the example of sodium capronate. [German] Die Positronen-Emissions-Tomographie (PET) ist eine etablierte Untersuchungsmethode zur Untersuchung von Stoffwechselvorgaengen im Menschen und wird als medizinisches Diagnoseverfahren (Stoffwechsel, Durchblutung, Metastasenerkennung) eingesetzt. Dieses Projekt beschaeftigt sich mit einer nichtmedizinischen Anwendung dieses bildgebenden Verfahrens - dem Aufbau und der Anwendung eines PET-Tomographen zur Untersuchung des Verhaltens von Schaum in Blasensaeulen, dem Versuchsstand SchaumPET. Insbesondere wird auf die technische Realisierung des Projektes und die angewendeten Verfahren zur Bildgewinnung eingegangen. Am Beispiel von Natriumcapronat wird gezeigt, dass sich die Anreicherung eines Tensids in einer Schaumschicht mit der Positronen-Emissions-Tomographie nachweisen laesst. (orig.)

  11. Gas generation from biomass for decentralized power supply systems; Gaserzeugung fuer dezentrale Energiesysteme auf der Basis von Biomasse

    Energy Technology Data Exchange (ETDEWEB)

    Kubiak, H.; Papamichalis, A.; Heek, K.H. van [DMT-Inst. fuer Kokserzeugung und Brennstofftechnik, Essen (Germany)

    1996-12-31

    By a reaction with steam, bioresidues and plants can be converted into a gas consisting mainly of hydrogen, carbon monoxide and methane which can be used for electric power generation in gas engines, gas turbins and fuel cells. The conversion processes, especially the fuel cell process, are environment-friendly and efficient. For decentralized applications (i.e. for biomass volumes of 0.5 to 1 t/h), an allothermal process is recommended which is described in detail. (orig) [Deutsch] Durch Reaktion mit Wasserdampf lassen sich Bioreststoffe und Energiepflanzen zu einem Gas umsetzen, das im wesentlichen aus Wasserstoff, Kohlenmonoxid und Methan besteht und z.B. ueber Gasmotoren, Gasturbinen, vorzugsweise aber Brennstoffzellen zu Strom umgewandelt werden kann. Die Umwandlungsverfahren, insbesondere unter Benutzung von Brennstoffzellen, sind umweltfreundlich und haben einen hohen Wirkungsgrad. Als Vergasungsverfahren eignet sich fuer die dezentrale Anwendung. - d.h. fuer eine Biomassemenge von 0,5 bis 1 t/h - insbesondere das hier beschriebene allotherme Verfahren. (orig)

  12. Odonaten von Sumatra, gesammelt von Edward Jacobson

    NARCIS (Netherlands)

    Ris, F.

    1927-01-01

    Die folgende Bearbeitung sumatranischer Libellen schliesst sich an zwei frühere Aufsätze über Libellen von Java und von Simalur an, die mir Herr Jacobson anvertraute. Die hier beschriebene wesentlich grössere Sammlung aus den Jahren 1913—15 kam gegen Ende 1920 in meine Hände, sie hätte also längst e

  13. Rheologie von Beschichtungen

    Science.gov (United States)

    Schäffler, Michael

    Die Rheologie beschreibt die Fließ- und Deformationseigenschaften von Materialien. Der Begriff Rheologie ist aus dem Griechischen abgeleitet: rhein - fließen. Erst im Jahre 1930 entwickelte E.C. Bingham und M. Reiner in Easton (USA) die Rheologie zu einer eigenständigen Wissenschaft. Aber bereits seit dem 17. Jahrhundert wurden wesentliche Einzelbeiträge zu Fließphänomenen veröffentlich, so z.B. 1676 von R. Hooke (Hookesches Gesetz) und 1687 von I. Newton (Newtonsches Gesetz). Die Rheologie hat sich bis heute immer mehr zu einer interdisziplinären Wissenschaft entwickelt, die die mechanischen Eigenschaften von Materialien charakterisiert.

  14. Nasal septum extramedullary plasmacytoma

    Directory of Open Access Journals (Sweden)

    Belić Branislav

    2013-01-01

    Full Text Available Introduction. Plasmacytomas are malignant tumors characterized by abnormal monoclonal proliferation of plasma cells. They originate in either bone - solitary osseous plasmacytoma, or in soft tissue - extramedullary plasmacytoma (EMP. EMP represents less than 1% of all head and neck malignancies. Case report. We presented a case of EMP of the nasal septum in a 44-year-old male who had progressive difficulty in breathing through the nose and frequent heavy epistaxis on the right side. Nasal endoscopy showed dark red, soft, polypoid tumor in the last third of the right nasal cavity arising from the nasal septum. The biopsy showed that it was plasmacytoma. Bence Jones protein in the urine, serum electrophoresis, bone marrow biopsy, skeletal survey and other screening tests failed to detect multiple myeloma. This confirmed the diagnosis of EMP. The mass was completely removed via an endoscopic approach, and then, 4 week later, radiotherapy was conducted with a radiation dose of 50 Gray. No recurrence was noted in a 3-year follow- up period. Conclusion. EMP of the nasal cavity, being rare and having long natural history, represents a diagnostic and therapeutic challenge for any ear, nose and throat surgeon. Depending on the resectability of the lesion, a combined therapy is the accepted treatment.

  15. Nasal valve surgery.

    Science.gov (United States)

    Apaydin, Fazil

    2011-04-01

    Nasal obstruction can be due to internal and external valve problems that can be seen before and after rhinoplasty. The main scope of this article is to concentrate on surgical solutions to these problems. To overcome nasal obstruction at the internal valve, spreader grafts, spreader flaps, upper lateral splay graft, butterfly graft, flaring suture, M-plasty, Z-plasty, and suspension sutures have been described. The management of the external valve problems is possible by using lateral crural dissection and repositioning, lateral crural strut grafts, alar battens, lateral crural turn-in flap, alar rim grafts, and various other methods. It is not easy to decide which techniques would work best in every case. After a thorough examination and analysis, the underlying cause of the nasal obstruction can be understood, and one or multiple procedures can be chosen according to each individual problem.

  16. Nasal spray flu vaccine (image)

    Science.gov (United States)

    The flu vaccine can also be administered as a nasal spray instead of the usual injection method. It can be ... the recombinant influenza vaccine (RIV). The nasal spray flu vaccine (live attenuated influenza vaccine or LAIV) should not ...

  17. Gebrauch von Komplementärmedizin bei Patienten mit metastasierendem Melanom unter Therapie mit Ipilimumab innerhalb einer klinischen Studie.

    Science.gov (United States)

    Huebner, Jutta; Mohr, Peter; Simon, Jan-Christoph; Fluck, Michael; Berking, Carola; Zimmer, Lisa; Loquai, Carmen

    2016-05-01

    In Deutschland wenden 40-90 % aller Krebspatienten Methoden der komplementären and alternativen Medizin (KAM) an. Bis dato gibt es kein Datenmaterial zum Einsatz der KAM bei Melanompatienten. Das Ziel unserer Studie war es, Daten über den Gebrauch, die Informationsquellen und Ziele von Patienten mit metastasierendem Melanom zu erfassen. Einhundertsechsundfünfzig Patienten aus 25 Studienzentren nahmen an der DecOG-MM-PAL Multibasket Studie teil. Die beteiligten Personen wurden auch gebeten, an einer Nebenstudie teilzunehmen, die ihren Gebrauch von KAM erfassen sollte. Dazu wurde während der Behandlung ein standardisierter Fragebogen zu genau festgelegten Zeitpunkten ausgeteilt. Insgesamt gingen 55 Fragebögen von 32 (21 %) Melanompatienten ein. Von diesen gaben 17 (53 %) ein Interesse an KAM an, und sieben (22 %) machten von KAM Gebrauch. Die Hauptinformationsquellen (31 %) waren Familienmitglieder und Freunde, gefolgt von Ärzten (19 %). Die Hauptgründe für die Anwendung von KAM waren die Stärkung des Immunsystems (41 %) und des Körpers (34 %). Nahrungsergänzungsmittel (Vitamine und Spurenelemente) wurden am häufigsten angewendet (28 %). Eine relativ hohe Anzahl an Patienten mit metastasierendem Melanom machte trotz Teilnahme an einer klinischen Studie von KAM Gebrauch. Wechselwirkungen könnten durch biologisch basierte KAM auftreten, und hier besonders bei immunmodulierenden KAM- Strategien. Um Risiken zu vermeiden, sollte die Kommunikation zwischen den Ärzten und den Patienten verbessert werden. © 2016 Deutsche Dermatologische Gesellschaft (DDG). Published by John Wiley & Sons Ltd.

  18. Von Triers kristendom

    DEFF Research Database (Denmark)

    Søndergaard, Leif

    2009-01-01

    Lars von Trier er i hans film Antichrist i sin negation af kristendommen stærkt bundet til kristendommens dualistiske verdensbillede. Samtidig er filmen kvindefjendsk. Udgivelsesdato: 2. september......Lars von Trier er i hans film Antichrist i sin negation af kristendommen stærkt bundet til kristendommens dualistiske verdensbillede. Samtidig er filmen kvindefjendsk. Udgivelsesdato: 2. september...

  19. Planung von Hochschulbibliotheken - Tagungsbericht

    Directory of Open Access Journals (Sweden)

    Felicitas Hundhausen

    2015-07-01

    Full Text Available Am 18. November 2014 veranstalteten das HIS-Institut für Hochschulentwicklung und die beiden Herausgeber des "Handbuchs Hochschulbibliothekssysteme", Konstanze Söllner und Wilfried Sühl-Strohmenger, in Hannover eine Tagung zum Thema "Planung von Hochschulbibliotheken". Hier ging es um ausgewählte Aspekte der Planung und Steuerung von Hochschulbibliotheken.

  20. Oligocaene Gastropoden von Buton

    NARCIS (Netherlands)

    Martin, K.

    1935-01-01

    Vor einiger Zeit besehrieb ich eine kleine, eigenartige Molluskenfauna aus tertiären Asphaltkalken von der unbedeutenden Insel Buton, im Südosten von Celebes¹). Seither empfing Herr Prof. Ir. Chr. K. Visser in Delft weitere Versteinerungen aus den Asphaltkalken des Eilands, die nach ihm wahrscheinli

  1. Mechanical/thermal dehydration - a new process for treatment of peat and coal; Mechanisch/Thermische Entwaesserung - ein neues Verfahren zur Veredelung von Torf und Kohlen

    Energy Technology Data Exchange (ETDEWEB)

    Bergins, C.; Berger, S.; Strauss, K. [Dortmund Univ. (Germany); Elsen, R.O. [RWE Energie, Essen (Germany); Erken, M. [Rheinbraun AG, Koeln (Germany); Bielfeldt, F.B. [Dieffenbacher, Eppingen (Germany)

    1998-09-01

    In order to keep German brown coal competitive, new technologies for enhanced efficiency of power generation from brown coal were developed in the past few years. At a water content of 50-60 percent by weight, much energy is lost for evaporation. Reduction of the water content will incur a 5 percent effiency enhancement. A new process was developed at Dortmund university, i.e. mechanical/thermal dehydration in which the water contained in brown coal is removed by heat and mechanical pressure. The process is described, and its applicability for other moist fuels, e.g. peat or waste from the paper and wood processing industry ist discussed. (orig./SR) [Deutsch] Damit Braunkohle in Deutschland als heimischer und subventionsfreier Energietraeger diesen Stellenwert behaupten und in Zukunft weiter ausbauen kann, wurde in den letzten Jahren verstaerkt die Entwicklung neuer Technologien zur Effizienzsteigerung der Braunkohleverstromung vorangetrieben. Bei der Verbrennung von Braunkohlen mit Wassergehalten von 50-60 Gew.-% ist in herkoemmlichen Kraftwerken ein erheblicher Teil des Energieinhaltes zur Verdampfung des Wassers mit Hilfe von heissen Rauchgasen in sogenannten Mahltrockungsanlagen erforderlich. Durch eine energetisch guenstige Reduzierung des Wassergehaltes vor der Verbrennung sind hier Wirkungsgradsteigerungen um bis zu 5 Prozentpunkte moeglich. Ein neues, fuer diese Aufgabenstellung einsetzbares Verfahren ist das am Lehrstuhl Energieprozesstechnik und Stroemungsmechanik der Universitaet Dortmund entwickelte Mechanisch/Thermische Entwaesserungsverfahren (MTE-Verfahren). Durch die kombinierte Anwendung von Waerme und mechanischem Druck laesst sich das in der Kohle enthaltene Wasser in fluessiger Form entfernen. Neben der Darstellung des MTE-Verfahrens am Beispiel von Braunkohle soll im folgenden auch auf die Moeglichkeiten der Anwendung des Verfahrens fuer andere feuchte Brennstoffe wie Torf und Abfaelle aus der Papier- und Holzverarbeitung eingegangen werden

  2. Lysosomal exoglycosidases in nasal polyps.

    Science.gov (United States)

    Chojnowska, Sylwia; Minarowska, Alina; Knaś, Małgorzata; Niemcunowicz-Janica, Anna; Kołodziejczyk, Paweł; Zalewska-Szajda, Beata; Kępka, Alina; Minarowski, Łukasz; Waszkiewicz, Napoleon; Zwierz, Krzysztof; Szajda, Sławomir Dariusz

    2013-01-01

    Nasal polyps are smooth outgrowths assuming a shape of grapes, formed from the nasal mucosa, limiting air flow by projecting into a lumen of a nasal cavity. Up to now the surgical resection is the best method of their treatment, but etiology and pathogenesis of the nasal polyps is not yet fully established. The aim of the study was the assessment of the selected lysosomal exoglycosidases activity in the nasal polyps. In this study the activity of β-galactosidase, α-mannosidase and α-fucosidase was determined in the tissue of the nasal polyps obtained from 40 patients (10F, 30M) and control tissues derived from mucosa of lower nasal conchas obtained during mucotomy from 20 patients (10F, 10M). We observed significant lower values of GAL, FUC and tendency to decrease of MAN and GLU concentration in nasal polyps (P) in comparison to control healthy nasal mucosa (C). In nasal polyp tissue (P) no differences of GAL, MAN and FUC specific activity in comparison to control mucosa (C) were found. Our research supports bioelectrical theory of the nasal polyps pathogenesis and directs attention at research on glycoconjugates and glycosidases of the nasal mucosa extracellular matrix. Copyright © 2013 Polish Otorhinolaryngology - Head and Neck Surgery Society. Published by Elsevier Urban & Partner Sp. z.o.o. All rights reserved.

  3. Nasalance Norms in Greek Adults

    Science.gov (United States)

    Okalidou, Areti; Karathanasi, Asimina; Grigoraki, Eleni

    2011-01-01

    The purposes of this study were to derive nasalance norms for monolingual Greek speakers, to examine nasalance scores as a function of gender and to draw cross-linguistic comparisons based on normative data. Participants read aloud a corpus of linguistic material, consisting of (1) a nasal text, an oral text and a balanced text; (2) a set of nasal…

  4. Nasalance Norms in Greek Adults

    Science.gov (United States)

    Okalidou, Areti; Karathanasi, Asimina; Grigoraki, Eleni

    2011-01-01

    The purposes of this study were to derive nasalance norms for monolingual Greek speakers, to examine nasalance scores as a function of gender and to draw cross-linguistic comparisons based on normative data. Participants read aloud a corpus of linguistic material, consisting of (1) a nasal text, an oral text and a balanced text; (2) a set of nasal…

  5. Nasal obstruction and human communication.

    Science.gov (United States)

    Malinoff, R; Moreno, C

    1989-04-01

    Nasal obstruction may cause a variety of communication disorders, particularly in children. The effects of nasal obstruction on hearing, speech, language, and voice are examined. Methods for assessing the effects of nasal obstruction are delineated, and recommendations for therapeutic interventions are described.

  6. Cosmetic and Functional Nasal Deformities

    Science.gov (United States)

    ... nasal complaints. Nasal deformity can be categorized as “cosmetic” or “functional.” Cosmetic deformity of the nose results in a less ... taste , nose bleeds and/or recurrent sinusitis . A cosmetic or functional nasal deformity may occur secondary to ...

  7. Study on the environmental behavior of cleaning products containing bacteria; Umweltvertraeglichkeit von Reinigern auf Bakterienbasis

    Energy Technology Data Exchange (ETDEWEB)

    Danneberg, G.; Tichy, H.V.; Simon, R.

    2000-03-01

    Cleaning products containing microorganisms were studied with a focus an products intended for the application in grease traps. Literature data available were compiled. Microbiological investigations were conducted with selected products. In addition laboratory experiments were performed in order to evaluate the capability of the products to support biodegradation of fatty compounds to CO{sub 2}. The influence on sewage quality was determined in a grease trap of a canteen with a selected product. (orig.) [German] Untersucht wurden Reinigungsprodukte, die Mikroorganismen enthalten und die insbesondere fuer den Einsatz in Fettabscheidern vorgesehen sind. Es wurden Literaturangaben ueber diese Produkte zusammengestellt. Ausgewaehlte Produkte wurden in Laborexperimenten mikrobiologisch untersuch. Weiterhin wurde im Laborversuch experimentell festgestellt, in wie weit diese Praeparate einen biologischen Abbau von Fetten zu CO{sub 2} bewirken koennen. In einem Praxisversuch an einem Fettabscheider wurde untersucht, wie sich die Abwasserqualitaet ohne und mit der Anwendung eines derartigen Praeparates verhaelt. (orig.)

  8. Herstellung von Chitosan und einige Anwendungen

    Science.gov (United States)

    Struszczyk, Marcin Henryk

    2001-05-01

    1. Die Deacetylierung von crabshell - Chitosan führte gleichzeitig zu einem drastischen Abfall der mittleren viscosimetrischen Molmasse ( Mv), insbesondere wenn die Temperatur und die Konzentration an NaOH erhöht werden. Diese Parameter beeinflussten jedoch nicht den Grad der Deacetylierung (DD). Wichtig ist jedoch die Quelle des Ausgangsmaterials: Chitin aus Pandalus borealis ist ein guter Rohstoff für die Herstellung von Chitosan mit niedrigem DD und gleichzeitig hoher mittlerer Mv, während Krill-Chitin (Euphausia superba) ein gutes Ausgangsmaterial zur Herstellung von Chitosan mit hohem DD und niedrigem Mv ist. Chitosan, das aus Insekten (Calliphora erythrocephala), unter milden Bedingungen (Temperatur: 100°C, NaOH-Konzentration: 40 %, Zeit: 1-2h ) hergestellt wurde, hatte die gleichen Eigenschaften hinsichtlich DD und Mv wie das aus Krill hergestellte Chitosan. Der Bedarf an Zeit, Energie und NaOH ist für die Herstellung von Insekten-Chitosan geringer als für crabshell-Chitosan vergleichbare Resultaten für DD und Mv. 2. Chitosan wurde durch den Schimmelpilz Aspergillus fumigatus zu Chitooligomeren fermentiert. Die Ausbeute beträgt 25%. Die Chitooligomere wurden mit Hilfe von HPLC und MALDI-TOF-Massenspektrmetrie identifiziert. Die Fermentationsmischung fördert die Immunität von Pflanzen gegen Bakterien und Virusinfektion. Die Zunahme der Immunität schwankt jedoch je nach System Pflanze-Pathogen. Die Fermentation von Chitosan durch Aspergillus fumigatus könnte eine schnelle und billige Methode zur Herstellung von Chitooligomeren mit guter Reinheit und Ausbeute sein. Eine partiell aufgereinigte Fermentationsmischung dieser Art könnte in der Landwirtschaft als Pathogeninhibitor genutzt werden. Durch kontrollierte Fermentation, die Chitooligomere in definierter Zusammensetzung (d.h. definierter Verteilung des Depolymerisationsgrades) liefert, könnte man zu Mischungen kommen, die für die jeweilige Anwendung eine optimale Bioaktivität besitzen. 3

  9. Environmental protection by cost minimization: Least Cost Planning for traffic. Includes a guide for the application in local communities; Umweltentlastung durch Kostenminimierung: Least Cost Planning im Verkehr. Mit Leitfaden fuer die Anwendung in Kommunen

    Energy Technology Data Exchange (ETDEWEB)

    Bracher, T.; Diegmann, V.; Eckart, C.F.; Liwicki, M.; Lobenberg, G.; Wetzel, C. [Gesellschaft fuer Informatik, Verkehrs- und Umweltplanung mbH (IVU), Berlin (Germany); Bergmann, M.; Uricher, A.; Lueers, A. [Oeko-Institut, Inst. fuer Angewandte Oekologie e.V., Freiburg im Breisgau (Germany); Becker, U.; Karl, G.; Karl, B.; Voellings, A. [Technische Univ. Dresden (Germany). Lehrstuhl fuer Verkehrsoekologie

    1999-08-01

    den Energiesektor entwickelte Least Cost Planning zu uebertragen. Auf der Basis einer Analyse der in der Literatur dokumentierten Ansaetze und der vorhandenen Bewertungsverfahren fuer oeffentliche Massnahmen wurden Anforderungen an Methodik und Entwicklung eines verbesserten Bewertungsverfahrens formuliert. Dieses muss verkehrsmitteluebergreifend (intermodal) und verkehrsuebergreifend (integriert) sein. Das entwickelte Verfahren ermoeglicht erstens die Darstellung der Verkehrsausgaben und Einnahmen einer Stadt im Jahresueberblick, und zweitens die vergleichende Bewertung von Planungsvarianten. Dies wurde anhand verschiedener Varianten fuer die Erschliessung eines Gewerbegebiets im Norden Freiburgs illustriert. Dabei wurden drei Varianten untersucht: die Verlaengerung einer Stadtbahnstrecke, die Verdichtung des Busverkehrsnetzes und die Einrichtung von Service-Stationen und weitere Foerdermassnahmen fuer den Fahrradverkehr. Neben den Berechnungen von Einnahmen und Ausgaben fuer jede Variante wurde eine uebersichtliche Darstellung von Auswirkungen auf die Verkehrsnachfrage, die Belastung mit Luftschadstoffen und Laerm sowie den Flaechenverbrauch entwickelt. Im Ergebnis schneidet die Erschliessung mit dem Fahrrad tendenziell guenstig ab. Der Abschlussbericht umfasst drei Baende sowie einen Leitfaden zur Anwendung des Verfahrens in Kommunen. Dazu gehoert ein Satz Tabellen im Excel Format, der die leichte Anwendung ermoeglicht. (orig.)

  10. Untersuchungen ueber den Bau von Orbitolina (Patellina auct.) von Borneo

    NARCIS (Netherlands)

    Martin, K.

    1884-01-01

    Vor einer Reihe von Jahren (1856—57) entdeckte Everwijn am Seberoeang, linken Nebenflusse des Kapoeas, in der West-Abtheilung von Borneo, Schichten mit Versteinerungen, welche von ihm für Nummuliten gehalten wurden. Der Fundort befand sich am rechten Ufer, 4—5 Kilometer von der Mündung des

  11. Calcitonin Salmon Nasal Spray

    Science.gov (United States)

    ... is important that you get enough calcium and vitamin D while you are using calcitonin salmon. Your doctor may prescribe supplements if your dietary ... examinations of the nose to make sure calcitonin salmon nasal spray is not ... such as vitamins, minerals, or other dietary supplements. You should bring ...

  12. Nasalization in Polish

    Science.gov (United States)

    Rubach, Jerzy

    1977-01-01

    This paper gives a complete account of vowel nasalization in Standard Polish. A distinction is made between obligatory and phonostylistic processes. Phonostylistic evidence may serve as a basis for making unambiguous decisions about the structure of underlying representations, intermediate phonological forms, and assimilation of borrowings to the…

  13. Nasal tooth: case report

    Energy Technology Data Exchange (ETDEWEB)

    Park, Si Hyun; Kim, Ji Hye; Hwang, Hee Young; Yang, Dal Mo; Kim, Hyung Sik; Park, Chol Heui [Gachon Medical School, Inchon (Korea, Republic of)

    2002-12-01

    Ectopic tooth is not uncommon and usually occurs in the palate and maxillary sinus. We report a case of ectopic tooth located in the nasal cavity, a rare site. The mass depicted by CT was highly attenuated, and central lucency was observed.

  14. Medienpädagogische Gestaltungsideen zur Integration von E-Learning in der Hochschullehre

    Directory of Open Access Journals (Sweden)

    Ricarda T.D. Reimer

    2003-08-01

    Full Text Available Im ersten Teil des Artikels geht die Autorin der Frage nach, welche Rolle E-Learning an Hochschulen einnimmt. Sie nennt Projekte, die vom Bund (teilweise mit kommerzieller Beteiligung gefördert werden und äußert die These, dass E-Learning didaktischer Konzepte bedarf und somit eine Aufwertung der Pädagogik bedeuten könnte. Im Zuge des Wettbewerbs unter den Hochschulen müssten sich wissenschaftliche MitarbeiterInnen mit der Konzeptualisierung von E- Learning und folglich mit mediendidaktischen Grundlagen auseinander setzen. Im Anschluss an diese, bildungstheoretischen Ausführungen beschreibt sie detailliert ein Seminar "Bildungstheorie in der Weiterbildung", das die Universitäten Bielefeld und Flensburg gemeinsam durchführten. Im Mittelpunkt stand die Anwendung von "blended learning". Präsenzelemente wurden von Online- Phasen abgelöst und begleitet. Das Seminar wurde evaluiert und kann somit Anstöße für weitere Konzepte geben.

  15. Entwicklung und Evaluation eines Algorithmus zur initialen Konfiguration von Anwendungen in PCOM

    OpenAIRE

    Reinsch, Michael

    2004-01-01

    In dieser Arbeit wird ein Algorithmus für das Komponentensystem PCOM entwickelt und evaluiert, welcher die initiale Konfiguration einer Anwendung in PCOM bestimmt. Eine Anwendung in PCOM besteht aus mehreren Komponenten, welche Zusammengesetzt die Anwendung ergeben. Diese Zusammensetzung wird als die Konfiguration der Anwendung bezeichnet. PCOM wurde in Hinblick auf Anwendungen in Ubiquitous Computing entworfen. Ubiquitous Computing ist charakterisiert durch eine verteilte, heterogene und,...

  16. A population based study on variations in the use of adjuvant radiotherapy in breast cancer patients; Bevoelkerungsbezogene Studie ueber die Anwendung adjuvanter Strahlentherapie bei Patientinnen mit Mammakarzinom

    Energy Technology Data Exchange (ETDEWEB)

    Nagel, G.; Katenkamp, D. [Feldstudie Mammakarzinom/Tumorzentrum, Univ. Jena (Germany); Roehrig, B.; Hoyer, H. [Institut fuer Medizinische Statistik, Informatik und Dokumentation, Univ. Jena (Germany); Fueller, J. [Klinik fuer Radiologie, Abteilung fuer Strahlentherapie, Friedrich-Schiller-Universitaet, Jena (Germany)

    2002-11-01

    beobachten. Fuer die uebrigen Kofaktoren wurden keine Assoziationen mit der Strahlentherapie beobachtet. Nach Mastektomie wurden 33,0% der Patientinnen adjuvant bestrahlt. Zunehmende Tumorgroesse war eine Indikation fuer die adjuvante Strahlentherapie. Ebenso hatten der Befall von mehr als drei Lymphknoten, Multifokalitaet, hoher Malignitaetsgrad und mediale Lokalisation Einfluss auf die Anwendung von Strahlentherapie. Hingegen konnte fuer die R-Klassifikation, den Hormonrezeptorstatus und Begleiterkrankungen kein Einfluss beobachtet werden. Zwischen den Kliniken waren hinsichtlich der Umsetzung von Therapieempfehlungen sowohl nach BET als auch Mastektomie Variationen zu beobachten. Schlussfolgerung: Nach BET wurde ueberwiegend die empfohlene Strahlentherapie durchgefuehrt, nur im hoeheren Alter und bei Begleiterkrankungen wurde seltener eine Strahlentherapie durchgefuehrt. Nach Mastektomie beeinflussten relevante Risikofaktoren die Therapieentscheidung zur Strahlentherapie. (orig.) (abstract truncated)

  17. Analgesic therapy of skeletal metastases with radionuclides; Schmerztherapie von Skelettmetastasen mit offenen radioaktiven Stoffen

    Energy Technology Data Exchange (ETDEWEB)

    Steinke, R.; Hartung, D.; Helmholz, T.; Otto, H.J. [Magdeburg Univ. (Germany). Medizinische Fakultaet

    2000-03-01

    The radionculide therapy of bone metastases is an unspecific palliative treatment of metastatic skeletal pain especially useful in patients suffering in multiple sites. In these cases the long-term administration of increasing doses of analgesics such as opiate which have important side effects can be reduced. The aim of this therapy is pain relief and improvement of quality of life in patients with advanced cancer. This report is focusing on options, indications and contraindications of the radionuclide therapy of metastases and on used radionuclides such as Strontium-89, Yttrium-90, Rhenium-186 (188) and Samarium-153. In oncology, the analgesic therapy using boneseeking radiopharmaceuticals in combination to drug adminstration shoud gain more importance because this therapy can be administered on an outpatient basis. (orig.) [German] Die nuklearmedizinische Strahlentherapie von Skelettmetastasen ist eine unspezifische, symptomatisch-palliative Schmerztherapie von ossaeren Metastasen. Sie ist insbesondere bei multiplen Lokalisationen eine erfolgreiche und kostenguenstige Therapieoption, die zu einer Einsparung von Analgetika, v.a. von stark nebenwirkungsbehafteten Opiaten, fuehren kann. Die palliative Schmerztherapie hat das primaere Ziel, bei einem in der Regel fortgeschrittenen Tumorleiden durch die Schmerzlinderung die Lebensqualitaet des Patienten deutlich zu verbessern. In der vorliegenden Arbeit werden die Moeglichkeiten, Indikationen und Kontraindikationen der Radionuklidtherapie vorgestellt und die einzelnen Radiopharmaka, die zur Anwendung kommen koennen (Sr-89, Y-90, Re-186[188], Sm-153), einander gegenuebergestellt. Die nuklearmedizinische Schmerztherapie, die haeufig noch zu weit im Hintergrund steht, sollte als Ergaenzung zur medikamentoesen Therapie weiter in den Blickpunkt der Onkologie gerueckt werden, da sie ohne stationaeren Aufenthalt auch von erfahrenen niedergelassenen Nuklearmedizinern durchgefuehrt werden kann. (orig.)

  18. Ellis Von Creveld Syndrome

    Directory of Open Access Journals (Sweden)

    Afshar H

    1999-01-01

    Full Text Available One patient with Ellis Von Creveld syndrome contains: dwarfism, congenital heart"ndisease, ectodermal dysplasia, polyductyly, an abnormally wide labial frenum and maxillary"nmolars with single root.

  19. Mycotic bovine nasal granuloma.

    Science.gov (United States)

    Conti Díaz, Ismael Alejandro; Vargas, Roberto; Apolo, Ada; Moraña, José Antonio; Pedrana, Graciela; Cardozo, Elena; Almeida, Edgardo

    2003-01-01

    A case of mycotic bovine nasal granuloma in a 10 year-old Jersey cow, produced by Drechslera halodes is presented. Histopathological sections showed abundant hyaline and pigmented extra and intracellular fungal structures together with a polymorphic cellular granuloma formed by neutrophils, lymphocytes, plasmocytes, histiocytes and giant cells of the Langhans type. It is the first case of mycotic bovine nasal granuloma recognized in Uruguay although this disease seems to be frequent according to the opinion of veterinarian specialists. Another similar clinical case also in a Jersey cow from the same dairy house with an intense cellular infiltrate rich in eosinophils without granulomatous image, together with extracellular hyaline and fuliginous fungal forms, is also referred for comparative purposes. Geotrichum sp. was isolated. The need of an early diagnosis and treatment of the disease is stressed.

  20. Lars von Triers film

    DEFF Research Database (Denmark)

    Nielsen, Lisbeth Overgaard

    2007-01-01

    Afhandlingen undersøger Lars von Triers filmæstetik, som den kommer til udtryk i spillefilmene fra perioden 1984-2007. Afhandlingen analyserer de enkelte films stil, virkningsstrategi og betydningsdannelse.......Afhandlingen undersøger Lars von Triers filmæstetik, som den kommer til udtryk i spillefilmene fra perioden 1984-2007. Afhandlingen analyserer de enkelte films stil, virkningsstrategi og betydningsdannelse....

  1. Kompressionstherapie - Versorgungspraxis: Informationsstand von Patienten mit Ulcus cruris venosum.

    Science.gov (United States)

    Protz, Kerstin; Heyer, Kristina; Dissemond, Joachim; Temme, Barbara; Münter, Karl-Christian; Verheyen-Cronau, Ida; Klose, Katharina; Hampel-Kalthoff, Carsten; Augustin, Matthias

    2016-12-01

    Eine Säule der kausalen Therapie bei Patienten mit Ulcus cruris venosum ist die Kompressionstherapie. Sie unterstützt die Abheilung, reduziert Schmerzen und Rezidive und steigert die Lebensqualität. Bislang existieren kaum wissenschaftliche Daten zu dem Versorgungsstand und fachspezifischem Wissen von Patienten mit Ulcus cruris venosum. Standardisierte Fragebögen wurden bundesweit in 55 Pflegediensten, 32 Arztpraxen, vier Wundzentren und -sprechstunden sowie einem Pflegetherapiestützpunkt von Patienten mit Ulcus cruris venosum bei Erstvorstellung anonym ausgefüllt. Insgesamt nahmen 177 Patienten (Durchschnittsalter 69,4 Jahre; 75,1 % Frauen) teil. Ein florides Ulcus cruris venosum bestand im Mittel 17 Monate. 31,1 % hatten keine Kompressionstherapie, 40,1 % Binden und 28,8 % Strümpfe. Bei der Bestrumpfung hatten 13,7 % Kompressionsklasse III, 64,7 % Kompressionsklasse II und 19,6 % Kompressionsklasse I. 70,6 % legten die Strümpfe nach dem Aufstehen an, 21,1 % trugen sie Tag und Nacht. 39,2 % bereiteten die Strümpfe Beschwerden. Lediglich 11,7 % hatten eine An- und Ausziehhilfe. Die Binden wurden im Mittel 40,7 Wochen getragen und bei 69 % nicht unterpolstert. Bei 2,8 % wurde der Knöchel- und Waden-Umfang zur Erfolgskontrolle gemessen. Venensport machten 45,9 %. Ein Drittel hatte keine Kompressionsversorgung, obwohl diese eine Basismaßnahme der Therapie des Ulcus cruris venosum ist. Zudem ist deren korrekte Auswahl und Anwendung angesichts der langen Bestandsdauer der Ulzerationen zu hinterfragen. Weiterführende Fachkenntnisse bei Anwendern und Verordnern sowie Patientenschulungen sind erforderlich. © 2016 Deutsche Dermatologische Gesellschaft (DDG). Published by John Wiley & Sons Ltd.

  2. Health risks associated with inhaled nasal toxicants

    NARCIS (Netherlands)

    Feron, V.J.; Arts, J.H.E.; Kuper, C.F.; Slootweg, P.J.; Woutersen, R.A.

    2001-01-01

    Health risks of inhaled nasal toxicants were reviewed with emphasis on chemically induced nasal lesions in humans, sensory irritation, olfactory and trigeminal nerve toxicity, nasal immunopathology and carcinogenesis, nasal responses to chemical mixtures, in vitro models, and nasal dosimetry- and me

  3. Investigation concerning the use of organic compost as a fertilizer in farming. Results of field tests using winter wheat, winter barley, winter rye, winter rape and sugar beet; Untersuchung ueber die Verwendung von Bio-Kompost als Kreislaufduenger im Landbau. Ergebnisse von Feldversuchen mit Winterweizen, Wintergerste, Winterroggen, Winterraps und Zuckerrueben

    Energy Technology Data Exchange (ETDEWEB)

    Oehmichen, J. [Paderborn Univ. (Gesamthochschule), Soest (Germany). Fachbereich 9 Landbau; Groeblinghoff, F.F. [Paderborn Univ. (Gesamthochschule), Soest (Germany). Fachbereich 9 Landbau; Reinders, A. [Paderborn Univ. (Gesamthochschule), Soest (Germany). Fachbereich 9 Landbau; Doerendahl, A. [Paderborn Univ. (Gesamthochschule), Soest (Germany). Fachbereich 9 Landbau

    1995-02-01

    At two farms, a test programme of several years` duration concerning the advantages of the application of organic compost was conducted. The problem of heavy metal contents was also dealt with. The article reports in detail on the test arrangements, nutritive effects observed, additional crop yield, and the value of the compost to be derived from this. At an annual application of 10 tonnes of compost per hectare, the limiting value for zinc would only be attained in more than 200 years` time. (orig.) [Deutsch] In zwei landwirtschaftlichen Betrieben wurde ein mehrjaehriges Versuchsprogramm ueber die Vorteile der Anwendung von Biokompost durchgefuehrt. Dabei wurde auch das Problem der Schwermetallgehalte behandelt. Ueber die Anlage der Versuche, die beobachtete Naehrstoffwirkung, die Mehrertraege und den daraus abzuleitenden Wert des Komposts wird ausfuehrlich berichtet. Eine alljaehrliche Kompostaufbringung von 10 t/ha wuerde erst in ueber 200 Jahren zum Erreichen der Grenzwerte fuer Zink fuehren. (orig.)

  4. Same Noses, Different Nasalance Scores: Data from Normal Subjects and Cleft Palate Speakers for Three Systems for Nasalance Analysis

    Science.gov (United States)

    Bressmann, Tim; Klaiman, Paula; Fischbach, Simone

    2006-01-01

    Nasalance scores from the Nasometer, the NasalView and the OroNasal System were compared. The data was collected from 50 normal participants and 19 hypernasal patients with cleft palate. The Nasometer had the lowest nasalance scores for the non-nasal Zoo Passage and that the OroNasal System had the lowest nasalance scores for the Nasal Sentences.…

  5. Energetisches Verhalten von Doppelfassaden

    OpenAIRE

    2002-01-01

    Durch die Forderung nach einer natürlichen Lüftung von Bürogebäuden und einem effektiven Sonnenschutz in Hochhäusern haben Doppelfassaden einen hohen Stellenwert erreicht. Das energetische Verhalten von Doppelfassaden ist Gegenstand zahlreicher Veröffentlichungen. Bisher liegen jedoch nur wenige Messungen in ausgeführten Gebäuden vor.Im Rahmen dieser Arbeit wurden drei Gebäude mit Doppelfassaden detailliert vermessen. Die Langzeitmessungen erfassten über mindestens ein Jahr unter anderem die ...

  6. Kontextualisierung von Queer Theory

    Directory of Open Access Journals (Sweden)

    Anna Voigt

    2008-03-01

    Full Text Available Christine M. Klapeer legt in diesem Einführungsband dar, aus welchen politischen und theoretischen Kontexten heraus sich ‚queer‘ zu einem Begriff mit besonderem politischem und theoretischem Gehalt entwickelt hat. Wesentlich zielt sie dabei auf eine kritische Kontextualisierung von „queer theory”. Die Autorin geht zunächst auf das Gay Liberation Movement ein, grenzt die Queer Theory vom Poststrukturalismus, von feministischen Theorien und den Lesbian and Gay Studies ab, beleuchtet Eckpunkte queeren Denkens und zeichnet schließlich die Entwicklungen in Österreich sowohl politisch-rechtlich als auch bewegungsgeschichtlich und in der Wissenschaftslandschaft nach.

  7. Use of modeling and simulation in the planning, analysis and interpretation of ultrasonic testing; Einsatz von Modellierung und Simulation bei der Planung, Analyse und Interpretation von Ultraschallpruefungen

    Energy Technology Data Exchange (ETDEWEB)

    Algernon, Daniel [SVTI Schweizerischer Verein fuer technische Inspektionen, Wallisellen (Switzerland). ZfP-Labor; Grosse, Christian U. [Technische Univ. Muenchen (Germany). Lehrstuhl fuer Zerstoerungsfreie Pruefung

    2016-05-01

    im Bauteil) an dessen akustischen Grenzflaeche interagieren. Aus dem an der Bauteiloberflaeche empfangenen Signal soll diese Interaktion erkannt und interpretiert werden, um Rueckschluesse auf das Vorhandensein des Zielobjektes zu ziehen sowie gegebenenfalls dessen Ausdehnung und Position (naeherungsweise) zu bestimmen. Obgleich die grundliegenden physikalischen Prinzipien der Anwendung elastischer Wellen in der ZfP bekannt sind, koennen komplexe Verhaeltnisse in Form von beschraenkter Zugaenglichkeit, Bauteilgeometrien oder Art und Form von Reflektoren die Durchfuehrung und Auswertung kompliziert werden lassen. So ist bereits die Abschaetzung der Erfolgsaussichten einer Pruefung oftmals nicht trivial. Diese Umstaende verdeutlichen die Bedeutung des Einsatzes von Simulationsrechnungen, die eine theoretisch fundierte Basis fuer die Pruefung ermoeglichen und mit denen sich Pruefsysteme optimieren lassen. Die dabei einsetzbaren Simulationsverfahren sind vielfaeltig. Gebraeuchlich sind insbesondere die Finite-Elemente-Methode, die Elasto Finite Integration Technique sowie semi-analytische Berechnungsverfahren.

  8. Definitive magnetic nasal prosthesis for partial nasal defect

    Directory of Open Access Journals (Sweden)

    E Nagaraj

    2011-01-01

    Full Text Available Maxillofacial trauma refers to any injury to the face or jaw caused by physical force, trauma, the presence of foreign objects, animal or human bites, and burns. Facial defects can be devastating in their impact on physical structure and function of the affected individual, leading to potential compromises in quality of life. Restoration of facial defects, especially nasal defects, is a difficult challenge for both the surgeon and the prosthodontist. Here is a case report of partial nasal defect caused by trauma, rehabilitated with a magnetic nasal prosthesis made with silicone elastomers using mechanical and anatomical retentive aids.

  9. Immunologische Effekte von Interferon beta und Glatiramerazetat in der Behandlung der Multiplen Sklerose

    Directory of Open Access Journals (Sweden)

    Berger T

    2008-01-01

    Full Text Available Die Multiple Sklerose (MS stellt die häufigste, potentiell behindernde neurologische Erkrankung im jungen Erwachsenenalter dar. Wiederkehrende Krankheitsschübe und/oder schleichende Krankheitsprogression kennzeichnen den klinischen Verlauf. Die histopathologischen Merkmale setzen sich aus einer chronischen Entzündungsreaktion, demyelinisierenden Herden sowie aus axonaler Schädigung im zentralen Nervensystem zusammen. In mehreren Phase-III-Studien wurde belegt, dass durch die Behandlung mit Interferon (IFN β und Glatiramerazetat (GA sowohl eine Reduktion der Schubrate als auch eine Reduktion von Krankheitsaktivitätsmarkern in der Magnetresonanztomografie bei MS erreicht werden kann. IFN β entfaltet seine Wirkung an mehreren Schnittstellen entlang der immunpathogenetischen Kaskade und verringert unter anderem die Aktivierung von autoreaktiven T-Lymphozyten sowie deren Migration durch die Blut-Hirn-Schranke. GA ist durch seine Fähigkeit, GA-spezifische Th2-Lymphozyten zu induzieren, imstande, pro-entzündliche Reaktionen, die durch autoreaktive T-Lymphozyten getriggert werden, in Richtung anti-entzündliche Immunantworten zu modulieren. Anhand der derzeit postulierten pathogenetischen Mechanismen bei MS werden immunologische und Aspekte der sicheren Anwendung beider Therapien besprochen.

  10. Energetische Verwertung von Biomasse

    Science.gov (United States)

    Zahoransky, Richard; Allelein, Hans-Josef; Bollin, Elmar; Oehler, Helmut; Schelling, Udo

    Etwa 0,1% der Solarenergie wandeln sich durch Photosynthese aus dem Kohlendioxid der Luft in Biomasse um. Die Biomassen sind als Festbrennstoff nutzbar oder zu gasförmigen Brennstoffen weiterverarbeitbar. Zwei Arten von Biomassen sind zu unterscheiden: Anfallende Biomasse

  11. Rhizostomeen von Manila

    NARCIS (Netherlands)

    Stiasny, G.

    1924-01-01

    Die hier beschriebene kleine Scyphomedusen-Sammlung wurde von Herrn Director P. B. Sivickis, Dept. of Zoology, University of Philippines, Manila, dem Rijksmuseum van Natuurlijke Historie in Leiden überwiesen. Das Material wurde im December 1922 in Manila-bay gefischt und befindet sich in bestem Erha

  12. Nasalization in Galician and Portuguese

    OpenAIRE

    Regueira Fernández, Xosé Luís

    2010-01-01

    Gallego y portugués compartieron una parte de su historia, y en su evolución el comportamiento de las nasales ha jugado un importante papel. El gallego contemporáneo no presenta nasalidad contrastiva (vocales orales vs nasales), mientras que si las tiene el portugués. En este trabajo muestro que la descripción de la coarticulación velar (o nasalización) de las vocales en contacto con sonorantes nasales es relevante para la descripción de las lenguas tanto gallega como portuguesa y, adem...

  13. Interactions between industrial organic pollutants and rhizosphere components and documentation of material streams in plant-based wastewater treatment plants - laboratory experiments; Wechselwirkungen industrieller organischer Schadstoffe mit Rhizosphaerenkomponenten und Bilanzierung von Stoffstroemen in Pflanzenklaeranlagen - Laborversuche

    Energy Technology Data Exchange (ETDEWEB)

    Plugge, J.

    2001-07-01

    The purpose of the present study was to examine the suitability of plant/soil systems for cleaning organically polluted effluents and to assess the influence of plant growth and dissolved humic substances on processes leading to the elimination of organic pollutants. This involved an examination of sorption interactions between selected pollutants on the one hand and sand and root material on the other, use of vertically irrigated plant-bearing sand columns for simulating real plant-based wastewater treatment plants, assessment of the cleaning efficiency of these systems with respect to the employed model pollutants and determination of the contamination of the filter material and plants with pollutants. Radiotracer techniques were used to determine pollution paths of phenanthrene and its microbial degradation in the model system. [German] In der vorliegenden Arbeit wurde die Eignung von Pflanze/Boden-Systemen zur Reinigung carbochemisch belasteter Abwaesser untersucht und der Einfluss eines Pflanzenbewuchses sowie geloester Huminstoffe auf die Prozesse, die zur Entfernung organischer Schadstoffe fuehren, bewertet. Die Bearbeitung dieses Themas umfasste Untersuchungen zu Sorptionswechselwirkungen ausgewaehlter Schadstoffe mit Sand- und Wurzelmaterial, die Anwendung vertikal durchstroemter, bepflanzter Sandsaeulen zur Nachbildung realer Pflanzenklaeranlagen, die Erfassung der Reinigungseffizienz dieser Systeme fuer die Modellschadstoffe sowie die Bestimmung der Schadstoffkontamination des Filtermaterials und der Pflanzen. Unter Anwendung der Radiotracertechnik erfolgte darueber hinaus die Bestimmung der Schadstoffpfade von Phenanthren einschliesslich des mikrobiellen Abbaus im Modellsystem. (orig.)

  14. Nasal Delivery of High Molecular Weight Drugs

    OpenAIRE

    Erdal Cevher; Yıldız Ozsoy; Sevgi Gungor

    2009-01-01

    Nasal drug delivery may be used for either local or systemic effects. Low molecular weight drugs with are rapidly absorbed through nasal mucosa. The main reasons for this are the high permeability, fairly wide absorption area, porous and thin endothelial basement membrane of the nasal epithelium. Despite the many advantages of the nasal route, limitations such as the high molecular weight (HMW) of drugs may impede drug absorption through the nasal mucosa. Recent studies have focused particula...

  15. Use of wastes in high-temperature processes of the chemical industry; Verwertung von Abfaellen in Hochtemperaturprozessen der chemischen Industrie

    Energy Technology Data Exchange (ETDEWEB)

    Seifert, H. [Forschungszentrum Karlsruhe GmbH Technik und Umwelt (Germany); Domschke, T.; Steinebrunner, K. [BASF AG, Ludwigshafen am Rhein (Germany)

    1998-09-01

    The examples presented in this paper from diverse application areas of the chemical industry serve as an illustration of the many different ways in which wastes can be used for high-temperature processes in this branch. A review of the environmentally friendly concepts implemented at BASF AG in Ludwigshafen in the course of the past five years gives an idea of the immense potential opened up by a consistent application of the four-stage model for the prevention, reduction, and utilisation of wastes. In this period it was possible to reduce waste arisings by 34%, down from a potential 2 million tons, physically recycle 51%, and convert 11.5% to energy. This left a comparatively small fraction of 3.5%, or 70,000 tons, to be disposed of in an environmentally acceptable way. Furthermore, the amount of pollutants produced per tonne of products sold fell from 40.6 kg in 1987 to 6.7 kg in 1997. [Deutsch] Die Beispiele aus den unterschiedlichsten Anwendungsbereichen der chemischen Industrie koennen als Auswahl der vielfaeltigen Verwertungsmoeglichkeiten von Abfaellen in Hochtemperaturprozessen der Chemie betrachtet werden. Das immense Potential, das sich durch konsequente Anwendung des 4-Stufen-Modells zur Vermeidung, Verminderung und Verwertung von Abfaellen eroeffnet, zeigt sich in einer Fuenfjahresbilanz der umgesetzten Umweltschutzbetrachtungen in der BASF AG in Ludwigshafen. So konnten in diesem Zeitraum von potentiellen 2 Mio t Abfall/a ca. 34% vermieden und vermindert, 51% stofflich und 11,5% energetisch verwertet werden, so dass nur noch ein geringer Anteil von 3,5%, entsprechend ca. 70000 t/a, umweltgerecht entsorgt werden musste. Dies fuehrte auch zu einer drastischen Reduktion der auf der Tonne Verkaufsprodukt bezogenen Menge an umweltbelastenden Stoffen von 40,6 kg im Jahre 1987 auf 6,7 kg im Jahre 1997. (orig.)

  16. Bilateral cleft lip nasal deformity

    OpenAIRE

    Singh Arun; Nandini R.

    2009-01-01

    Bilateral cleft lip nose deformity is a multi-factorial and complex deformity which tends to aggravate with growth of the child, if not attended surgically. The goals of primary bilateral cleft lip nose surgery are, closure of the nasal floor and sill, lengthening of the columella, repositioning of the alar base, achieving nasal tip projection, repositioning of the lower lateral cartilages, and reorienting the nares from horizontal to oblique position. The multiplicity of procedures in the li...

  17. Coarticulation effects on the nasalization of vowels using nasal/voice amplitude ratio instrumentation.

    Science.gov (United States)

    Larson, P L; Hamlet, S L

    1987-10-01

    Nasal coarticulation in phonetically controlled nonsense syllables was investigated in four normal adult speakers. Nasalization was determined using the ratio of a nasal accelerometer signal amplitude to airborn microphone signal amplitude. Measurements of nasalization were made at the midpoint of vowels and at a constant time from the nasal consonant. Nasal acoustical coupling was greater for high vowels than for low vowels in all consonant contexts. Nasalization was also greater for vowels between two nasal consonants than for vowels between a nasal consonant and a fricative or stop. Results for progressive versus regressive assimilation depended on the measurement strategy. For within-vowel measurements made a constant time from the nasal consonant, prenasal vowels showed greater nasalization than postnasal vowels. This nasal accelerometric technique shows promise for clinical assessment of articulatory details of velar function.

  18. Angioleiomyoma of the Nasal Cavity

    Directory of Open Access Journals (Sweden)

    Arruda, Milena Moreira

    2014-01-01

    Full Text Available Introduction Vascular leiomyoma of the nasal cavity is an extremely rare tumor that represents less than 1% of all vascular leiomyomas. It is more prevalent in women between the fourth and sixth decades, reaching primarily the inferior nasal turbinates. Objectives Reporting and assisting the systematization of more accurate diagnostic methods in clinical and complementary investigation of vascular leiomyoma in the nasal cavity. Resumed Report We present the case of a 49-year-old woman diagnosed with vascular leiomyoma in the nasal cavity, which manifested mainly with nasal obstruction. During investigation, computer tomography was not diagnostic, the cytologic study was not conclusive, and according to the biopsy, it was a squamous papilloma. Conclusion We suggest that the technical difficulty in obtaining an adequate amount of material for preoperative biopsy, associated with the topography of the lesion in the vestibular nasal region, may have contributed to changing the postoperative diagnosis. Thus, pathologic study of the surgical fragment is the more accurate method for diagnosis.

  19. Angioleiomyoma of the Nasal Cavity

    Science.gov (United States)

    Arruda, Milena Moreira; Monteiro, Daniela Yasbek; Fernandes, Atilio Maximino; Menegatti, Vanessa; Thomazzi, Emerson; Hubner, Ricardo Arthur; Lima, Luiz Guilherme Cernaglia Aureliano de

    2014-01-01

    Introduction Vascular leiomyoma of the nasal cavity is an extremely rare tumor that represents less than 1% of all vascular leiomyomas. It is more prevalent in women between the fourth and sixth decades, reaching primarily the inferior nasal turbinates. Objectives Reporting and assisting the systematization of more accurate diagnostic methods in clinical and complementary investigation of vascular leiomyoma in the nasal cavity. Resumed Report We present the case of a 49-year-old woman diagnosed with vascular leiomyoma in the nasal cavity, which manifested mainly with nasal obstruction. During investigation, computer tomography was not diagnostic, the cytologic study was not conclusive, and according to the biopsy, it was a squamous papilloma. Conclusion We suggest that the technical difficulty in obtaining an adequate amount of material for preoperative biopsy, associated with the topography of the lesion in the vestibular nasal region, may have contributed to changing the postoperative diagnosis. Thus, pathologic study of the surgical fragment is the more accurate method for diagnosis. PMID:25992133

  20. Abschied von Ingeborg Pomp

    OpenAIRE

    Hänsel, Rosemarie

    2007-01-01

    Am 4. Juni 2007 erhielten wir die traurige Nachricht, dass Ingeborg Barbara Pomp, Leiterin i. R. der Stenografischen Sammlung von 1996 bis 2006 nach kurzer schwerer Krankheit verstorben ist. Die Mitarbeiterinnen und Mitarbeiter der Sächsischen Landesbibliothek – Staats- und Universitätsbibliothek trauern um eine liebenswerte Kollegin, die sich immer mit einem Höchstmaß an persönlichem Einsatz für die Weiterentwicklung der Stenografischen Sammlung engagiert hat.

  1. Materials engineering. Pt. 2. Applications. 4. upd. ed.; Werkstofftechnik. T. 2. Anwendung

    Energy Technology Data Exchange (ETDEWEB)

    Bergmann, Wolfgang [Technische Univ. Berlin (Germany). Inst. fuer Werkstofftechnik

    2009-07-01

    The second part of this textbook provides a detailed introduction to modern materials engineering for students. Subjects: (E) Materials production (metals, plastics, ceramics, glass); (F) Working of materials (metals, plastics, inorganic non-metals, effects of working on materials characteristics); (G) Applications (protection against corrosion, scaling, and wear; lightweight construction; materials in mechanical engineering; product engineering; transportation and traffic; energy engineering and chemical engineering; electrical engineering). (orig.) [German] Der zweite Band des Lehrbuches der Werkstofftechnik ist als eine umfassend angelegte Einfuehrung in die moderne Werkstofftechnik fuer Studenten gedacht und ist wie folgt gegliedert: (E) Werkstoffherstellung (Herstellung von Metallen, Kunststoffen, Keramik und Glas); (F) Werkstoffverarbeitung (Metallische Werkstoffe - Kunststoffe - Nichtmetallisch anorganische Werkstoffe - Verarbeitungsbedingte Eigenschaftsaenderungen); (G) Werkstoffanwendung (Korrosions-, Verzunderungs-, Verschleissschutz - Leichtbau - Werkstoffe in Maschinenbau, Fertigungstechnik, Verkehrswesen, Energie-/Verfahrenstechnik und Elektrotechnik). (orig.)

  2. A entomoftorose nasal

    Directory of Open Access Journals (Sweden)

    Zilton A. Andrade

    1972-10-01

    Full Text Available São apresentados os dados clínico-patológicos de dois casos de entomoftorose nasal, nova doença humana causada por um ficomiceto - Entomophthora coronata. Os pacientes, uma menina e um homem, com 8 e 44 anos de idade respectivamente, apresentaram doença localizada, com nódulos no nariz e região paranasal, edema e deformação da face. O parasito foi isolado do primeiro caso, mas todas as tentativas para isolá-lo no segundo caso resultaram negativas. Histologicamente, havia reação granulomatosa, fibrose e edema, em torno de hifas não septadas, as quais exibiam envólucro eosinófilo amorfo em torno. Foram demonstrados anticorpos circulantes contra, as hifas do E. coronata no soro de um dos pacientes. O material eosinófilo em torno das hifas continha fibrina e material auto-fluorescente sob luz ultra-violeta, provavelmente lipofuscina, mas não foram demonstrados anticorpos ou antígenos nesta área. A apresentação destes casos, os primeiros a serem descritos no Brasil, é acompanhado, de uma revisão geral do assunto, pois tal poderá vir a ser de interesse para aqueles que estudam os problemas da patologia tropical em nosso meio.

  3. Applications of CO{sub 2} in supermarket systems. System design and control; Anwendung von CO{sub 2} in Supermarktsystemen. Anlagendesign und Steuerung

    Energy Technology Data Exchange (ETDEWEB)

    Javerschek, Oliver [Bitzer Kuehlmaschinenbau GmbH, Sindelfingen (Germany)

    2009-01-15

    The contribution outlines various system solutions which are based exclusively on CO{sub 2} as refrigerant. For safe and efficient operation of these systems, appropriate measures must be taken concerning system design and control. With a view to compressors for transcritical applications of CO{sub 2}, the focus is on power control, operating temperatures, and oil management. Further, the use of parallel compression is discussed and simulations are compared with performance measurements. (orig.)

  4. Application of PZT thin film technology for angular resolved flame detection; Anwendung von pyroelektrischen PZT-Duennschichten fuer die winkelaufloesende Flammendetektion

    Energy Technology Data Exchange (ETDEWEB)

    Neumann, Norbert; Ebermann, Martin; Hoppe, Silke [InfraTec GmbH, Dresden (Germany)

    2012-07-01

    Hot gases emit a specific spectral pattern in the infrared range at about 4.3 {mu}m, which can be sensed with an infrared (IR) flame detector. State-of-the-art detectors are designed as single-point detectors to detect a flame inside a certain field of view where the position of the flame cannot be resolved. The novel 3 x 3 array sensor delivers additional spatial information about the observed scene for an angular location of the flame with a resolution of about 5 . (orig.)

  5. Entwicklung und Anwendung von UHPLC-MS Verfahren für organische Spurenstoffe zur Bewertung der Sicherheit der Rohwasserressourcen der Wasserwerke der Stadt Berlin

    OpenAIRE

    van Baar, Patricia

    2015-01-01

    Gegenstand der vorliegenden Arbeit war die Erstellung eines Untersuchungsprogramms zur Bewertung der Rohwasserressourcen der Berliner Wasserwerke. Zu diesem Zweck wurden geeignete UHPLC-MS Verfahren für die Target und Non-Target Analytik entwickelt. Für die Target Analytik wurde eine UHPLC-MS/MS Multimethode erstellt, die sich als sensitives, schnelles und kostengünstiges Verfahren erwiesen hat. Das Verfahren beruhte auf Direktinjektion im multiple reaction monitoring (MRM)-Modus. Auch ohne P...

  6. Shopping centers and refrigeration. Exploiting cost-saving potentials through consistent use of innovative plant concepts; Supermarktkuehlung. Realisierung von Kosten-Einsparpotentialen durch konsequente Anwendung innovativer Anlagenkonzepte

    Energy Technology Data Exchange (ETDEWEB)

    Zaremski, W. [Copeland GmbH, Frankfurt am Main (Germany)

    1999-04-01

    Immense cost pressure has prompted major German chain stores in recent years to base their decisions on technical systems on the sole criterion of investment cost. Expenditure for current operation, maintenance and repair, which is by no means negligible, was left almost entirely out of consideration. (orig.) [Deutsch] Enormer Kostendruck hat in den vergangenen Jahren die grossen deutschen Handelsketten immer haeufiger dazu bewogen nur die Anlageninvestitionskosten als Entscheidungskriterium fuer die Technikauswahl zu sehen. Fast gaenzlich unbeachtet blieben die nicht unerheblichen Aufwendungen fuer den laufenden Betrieb, die Wartung und die Instandsetzung. (orig.)

  7. Application of biotests for the characterization of exposure pathways for endocrine disrupters from plastics; Anwendung von Biotests zur Charakterisierung der Expositionspfade fuer Umwelthormone aus Kunststoffen

    Energy Technology Data Exchange (ETDEWEB)

    Wagner, Martin; Oehlmann, Joerg [Frankfurt Univ., Frankfurt am Main (Germany). Abteilung Aquatische Oekotoxikologie

    2011-12-15

    The present project aims to characterise the exposure pathways for endocrine disruptors from plastic materials. A bioassay-based approach was employed to investigate and characterise the endocrine activity. Migration studies with food packaging and plastic preforms document the leaching of estrogen-like compounds from several types of plastic in the Yeast Estrogen Screen and the E-Screen. Additionally, anti-estrogenic activity was predominant in many samples. The detection of complex migration profiles provides evidence for the leaching of several, diverse-acting endocrine disruptors. Moreover, extracts of plastic food packaging exhibited agonistic activity on the estrogen receptor, retinoid X receptor, and vitamin D receptor. A theoretical exposure assessment for marine molluscs implies that endocrine disruptors from plastic might induce relevant effect in the environment. Within the exemplary investigation of bottled mineral water, 60% of the products were characterised as significantly estrogenic using the YES and E-Screen. These in vitro data point to the plastic packaging being one source of estrogenic contamination. An in vivo study employing the estrogen-sensitive model organism Potamopyrgus antipodarum supports this hypothesis. By using several analytical techniques (GC-MS, LC-MS/MS) we identified several well-known endocrine disruptors in bottled water and the plastic material, e.g. numerous phthalates and phenols. Moreover, potent antagonists of the estrogen and androgen receptor were extracted from bottled water. In a non-target analysis (Orbitrap-MS) a compound with the exact mass of 363.1992 [M+H{sup +}] correlated highly significantly with the biological activity. On the basis of the methods optimised and applied within the project we elaborated a set of aspects that are crucial for the applicability of bioassays to characterise the endocrine activity of complex samples. Employing a bioassay-based approach we provide evidence for the presence and migration of endocrine disruptors from plastic materials. In that sense, polymers represent a relevant but currently neglected source of human and environmental exposure to endocrine active compounds. Concerning the identification and toxicological characterisation of those chemicals, there is substantial need for further research. (orig.)

  8. DIE NEUREGELUNG DES IFRS 10 ZUR ABGRENZUNG DES KONSOLIDIERUNGSKREISES – DIE ANWENDUNG DES EINHEITLICHEN BEHERRSCHUNGSMODELS AUF DIE ERFASSUNG VON STRUKTURIERTEN UNTERNEHMEN IM KONZERNABSCHLUSS

    OpenAIRE

    Markus Häfele

    2013-01-01

    In the past entities varied in their application of the control concept (IAS 27 and SIC-12) in circumstances in which a reporting entity controls another entity but holds less than a majority of the voting rights of the entity, and in circumstances involving agency relationships (IFRS 10.IN3). This conflict between IAS 27 and SIC-12 had led to inconsistent application of the concept of control. IAS 27 required the consolidation of entities that are controlled by a reporting entity, and it def...

  9. Application of molecular calcium compounds in catalysis and hydrogen storage; Anwendung von molekularen Calcium-Verbindungen in der Katalyse und der Wasserstoffspeicherung

    Energy Technology Data Exchange (ETDEWEB)

    Spielmann, Jan

    2010-07-20

    1. Applications in catalysis: In the course of this work new catalytic applications of calcium compounds and in particular hydrocarbon-soluble calcium hydride species have been investigated. The complex [(DIPP-nacnac)CaH(THF)]2 (1, DIPP-nacnac = HC[C(Me)N-2,6-(i-Pr)-C6H3]2) served as a model system to test reactivity of the calcium hydride in stoichiometric reactions on a molecular level. It has been found that the hydroboration of conjugated alkenes with catecholborane can be accelerated considerably by using catalytic amounts of calcium complexes. However it was shown that calcium hydride species catalyze the decomposition of catecholborane to BH3 which is probably the catalytically active species. Investigations on the catalytic hydrosilylation of ketones have demonstrated that calcium complexes are efficient catalysts for this reaction. In the proposed catalytic cycle of this reaction six-coordinate hypervalent silicon species play a crucial role. Furthermore it has been shown that molecular calcium compounds are catalysts for the hydrogenation of conjugated alkenes with H2 under relatively mild conditions (20 bar H2, 20 C). Both steps in the proposed catalytical cycle i.e. addition of a metal hydride to the C=C double bond and a heterolytic cleavage of H2 by a calcium alkyl compound have been confirmed experimentally. 2. Applications in hydrogen storage: Ligand stabilized metal amidoborane complexes in the form of (DIPP-nacnac)MNH(R)BH3(THF)x (M = Ca, Mg; R = H, Me, i-Pr, 2,6-(i-Pr)-C6H3; x = 0, 1, 2) have been synthesized and structurally characterized. These complexes are model systems for the metal amidoborane compounds M(NH2BH3)n (M = Li, Na, n = 1; M = Ca, n = 2), which are potential high capacity hydrogen storage materials. To get insights in their dehydrogenation mechanisms the thermal decomposition of the model compounds was investigated in solution. This allowed for the first isolation of well-defined dehydrogenated products which have been structurally characterized. Depending on the metal and the sterical bulk of the substituent R the decomposition resulted in the clean formation of complexes with either a central dianionic [N(R)-BH-N(R)-BH3]2--unit (R = H, Me, i-Pr), a compound containing a borylamide [N(R)=BH2]- (R = 2,6-(i Pr)-C6H3) or a metal hydride complex. For the observed products mechanisms of their formation have been proposed and experimentally confirmed. In these mechanisms metal hydride species play a key role. The favoured decomposition pathway leads to formation of compounds with the central dianionic [N(R)-BH-N(R)-BH3]2--unit. Additionally a magnesium-catalyzed synthetic route to a bis(amino)borane HB[NH(DIPP)]2 has been developed which can form a novel boramidinate ligand {l_brace}HB[N(2,6-(i-Pr)-C6H3)]2{r_brace}2- by double deprotonation. Furthermore a preparative useful synthetic route to zinc and aluminium hydride complexes based on the use of amidoborane compounds has been described. By using novel bis({beta}-diketiminate) ligands it has been possible to prepare dinuclear magnesium amidoborane complexes. The investigation of their thermal decomposition gave important information on aggregation effects of the complexes during the dehydrogenation. As a decomposition product of a N-substituted, dinuclear magnesium amidoborane complex a tetranuclear magnesium hydride complex has been isolated in low yields. Alternatively such compounds have been prepared in good yields by reaction of a n butylmagnesium precursor with phenylsilane. This synthetic approach allowed also the preparation of an octanuclear magnesium hydride complex with a central paddle-wheel shaped [Mg8H10]-unit. These multinuclear magnesium hydride complexes could be considered as ligand-stabilized forms of MgH2 and could be valuable model systems for investigations on MgxHy-hydrogen storage materials. (orig.)

  10. Application of transient numeric simulation methods for calculating aeroacoustic sources of noise in axial blowers; Anwendung von instationaeren numerischen Simulationsmethoden zur Berechnung aeroakustischer Schallquellen bei Axialventilatoren

    Energy Technology Data Exchange (ETDEWEB)

    Reese, H.

    2007-07-01

    The publication intends to contribute to the calculation of aeroacoustic noise of axial blowers. Using the example of a typical low-pressure axial blower, the transient flow field, aeroacoustic sound waves and noise emissions are calculated. Four methods of numeric flow simulation are used, each with a different degree of approximation. In order to investigate different noise development mechanisms, flow to the blower rotor was investigated in the undisturbed state and in a highly turbulent state. Low-frequency noise as a rule is dominated by mechanisms like secondary flow or turbulent inflow which can be predicted rather well by numeric simulations of medium accuracy. Higher-frequency noise resulting from the turbulent boundary layer can only be predicted by large eddy simulation, which is quite time-consuming. (orig.)

  11. Clinical use of 'ROTOP-NEUROSPECT' in several brain diseases. Die klinische Anwendung von 'ROTOP-NEUROSPECT' bei verschiedenen hirnorganischen Erkrankungen

    Energy Technology Data Exchange (ETDEWEB)

    Wuensche, A.; Kaempfer, I.; Loessner, J.; Wagner, A.; Dietrich, J.; Strauss, I.; Neumann, G.; Otto, L.; Koegler, A.; Schenk, S.; Schneider, G. (Leipzig Univ., Klinik fuer Radiologie, Abt. Nuklearmedizin (Germany) Leipzig Univ. (Germany). Klinik fuer Neurologie Leipzig Univ. (Germany). Klinik fuer Neurochirurgie Bezirkskrankenhaus fuer Psychiatrie, Leipzig-Doesen (Germany))

    1990-01-01

    We proofed the suitibility of ROTOP-NEUROSPECT (R*) (HMPAO) from Rossendorf for consideration of disturbed brain circulation in 42 patients. Results we compared with morphological methods (X-ray computing tomography, angiography) and with clinical and neurological findings. We found often a disturbed brain circulation in emission computing tomography (SPECT) before morphological changes in X-ray computing tomography (CT). ROTOP-NEUROSPECT (R*) from Rossendorf is very well for consideration of disturbed brain circulation, we did not see quality differences between ROTOP-NEUROSPECT and CERETEC from Amersham. Activity accumulations in the liver and gall of both radiopharmaceuticals did not influence the test, because of the big distance to the brain. (orig.).

  12. Heating energy required for the electric heating of a resting pen for sucking pigs. Notwendiger Heizenergieeinsatz bei Anwendung der elektrisch beheizten Ferkelliegeflaeche zur Aufzucht von Saugferkeln

    Energy Technology Data Exchange (ETDEWEB)

    Bresk, B.; Rehmann, U. (Institut fuer Angewandte Tierhygiene, Eberswalde-Finow (German Democratic Republic))

    1988-01-01

    The authors present the results of measurements performed on the surface and plate inner temperatures, and on heat dissipation and input in an electrically heated piglet resting pen. Based on a working hypothesis and on a combination of the measurement results and literature findings, the authors derive an equation to calculate the required energy input in dependence from piglet age and stable-air temperature. (orig.).

  13. Erfassung von Bodenerosion in der Schweiz : vergleichende Anwendung verschiedener Methoden und Beurteilung ihrer Eignung für den Vollzug der Bodenschutzgesetzgebung

    OpenAIRE

    Ogermann, P.; B. Hebel; V. Prasuhn; Weisshaidinger, R.

    2006-01-01

    In der Schweiz existiert eine umfassende Gesetzgebung für den Schutz der Ackerflächen vor Bodenerosion durch Wasser. Es fehlen aber einheitliche, verbindliche Vorgaben sowie ein für die ganze Schweiz validiertes Verfahren für den Vollzug dieser gesetzlichen Regelungen durch die Kantone. Im Artikel werden unterschiedliche Methoden zur Erfassung der Bodenerosion in zwei Untersuchungsgebieten vergleichend angewendet. Drei angewendete Modellansätze (Allgemeine Bodenabtragsgleich...

  14. Laser drilling of collagen. A medical technique application for the excimer laser. Laserbohren von Kollagen. Eine medizintechnische Anwendung fuer den Excimer-Laser

    Energy Technology Data Exchange (ETDEWEB)

    Dickmann, K. (Laser Zentrum Hannover e.V. (Germany))

    1989-12-01

    For a special medical application in the field of clinic thrombocyte diagnosis drills in collagen - an extremely temperature sensitive organic material - are required without any thermal damage of the material. Thus processing of collagen based on mechanical drilling failed and furthermore also CO{sub 2}- and Nd:YAG-laser drilling was not practicable due to the thermal interaction mechanism of the infrared laser radiation with the material. However, drilling of collagen by the use of excimer laser radiation at {lambda} = 193 nm has shown a sharp-edged drill contour without any thermal damage of the material, as has been proved in recent medical tests. (orig.).

  15. The use of radioactive materials in German schools. Obstacles and chances; Anwendung von radioaktiven Stoffen in Schulen in Deutschland. Hindernisse und Chancen

    Energy Technology Data Exchange (ETDEWEB)

    Vahlbruch, Jan-Willem [Hannover Univ. (Germany). Inst. fuer Radiooekologie und Strahlenschutz

    2015-07-01

    The basics for the understanding of radioactivity and radioprotection are set in the secondary school. Therefore the German-Swiss Radiation Protection Association already is trying to support the appropriate teaching of relevant topics in school for a long time. Unfortunately experiments with radioactive material are hampered in Germany by complex and confusing legislation. In this contribution the framework is described which is given by the German legislation for the use of radioactive sources in secondary schools. Additionally proposals for different simple experiments with radioactivity are presented which can be easily implemented in teaching and alternative methods are introduced like e.g. virtual experiments.

  16. Image diagnosis of nasal bone fracture

    Energy Technology Data Exchange (ETDEWEB)

    Hirota, Yoshiharu; Shimizu, Yayoi; Iinuma, Toshitaka.

    1988-04-01

    Twenty cases of nasal bone fractures were evaluated as to the types of fractures based upon HRCT findings. Conventional X-Ray films for nasal bones were analyzed and compared with HRCT findings. Nasal bone fractures were classified into lateral and frontal fractures. HRCT images were evaluated in three planes including upper, middle and lower portions of the nasal bone. Fractures favored males of teens. Lateral fracture gave rise to the fractures of the nasal bone opposite to the external force, loosening of the ipsilateral nasomaxillary sutures and fractures of the frontal process of the maxilla. Conventional X-Ray films were reevaluated after HRCT evaluation and indications of nasal bone fractures were determined. In addition to the discontinuity of the nasal dorsum, fracture lines parallel to and beneath the nasal dorsum and indistinct fracture lines along the nasomaxillary sutures are the indication of nasal bone fractures by conventional X-Ray films.

  17. Evaluation and prevention of self-ignition and emission of combustion gases during storing bulk goods and landfill materials; Beurteilung und Verhinderung von Selbstentzuendung und Brandgasemission bei der Lagerung von Massenschuettguetern und Deponiestoffen

    Energy Technology Data Exchange (ETDEWEB)

    Schossig, Joerg; Berger, Anka; Malow, Marcus; Krause, Ulrich

    2010-05-27

    The authors of the contribution under consideration report on a new method for the risk assessment for self-ignition with the storage of bulk goods, landfill materials and recycling materials. This method consists of three components: (a) Experimental determination of the relevant physicochemical characteristics of the material; (b) Experimental determination of the reaction behaviour by means of thermal analysis behaviour; (c) Prediction of the self-ignition and the process of combustion. Fundamental realizations to the thermal behaviour and reaction behaviour of recycling storages were obtained. Thus, mixtures from plastics with cellulose containing or fibre-like materials or with inert materials, respectively, have an increased danger to self-ignition in comparison to pure plastics. A dangerous heat release also is observed with very small portions of inflammable materials. Under consideration of heterogeneous distribution of the inflammable components, the ignition can be transferred between inflammable inclusions. By means of a mathematical model, self-inflammation processes can be protected in arbitrary arrangements of the recycling storages. [German] Im Ergebnis des Vorhabens steht fuer die praktische Anwendung eine wissenschaftlich fundierte Methode der Gefahrenbewertung fuer Selbstentzuendungsvorgaenge bei der Lagerung von Massenschuettguetern, Deponiestoffen und Recyclingmaterialien zur Verfuegung. Diese Methode besteht aus drei Bestandteilen: - Experimentelle Bestimmung der relevanten physiko-chemischen Eigenschaften des Materials, - Experimentelle Bestimmung des Reaktionsverhaltens mittels thermischer Analyseverfahren, - Vorhersage der Selbstentzuendung und des Brandverlaufes durch numerische Simulation anhand der realen Geometrie der Lageranordnung. Eine solche Methode wurde bisher nicht systematisch angewendet, weshalb sowohl bei der Erstellung von Brandschutzkonzepten durch die Betreiber von Deponien oder Recyclinglagern als auch bei der Genehmigung

  18. Nutzerorientiertes Management von materiellen und immateriellen Informationsobjekten

    OpenAIRE

    Hübsch, Chris

    2001-01-01

    Schaffung einer stabilen, erweiterbaren und skalierbaren Infrastruktur für die Bereitstellung von Diensten im Umfeld von Bibliotheken und ähnlichen wissensanbietenden Einrichtungen unter Verwendung von XML-RPC und Python.

  19. Nutzerorientiertes Management von materiellen und immateriellen Informationsobjekten

    OpenAIRE

    Hübsch, Chris

    2001-01-01

    Schaffung einer stabilen, erweiterbaren und skalierbaren Infrastruktur für die Bereitstellung von Diensten im Umfeld von Bibliotheken und ähnlichen wissensanbietenden Einrichtungen unter Verwendung von XML-RPC und Python.

  20. Bilateral cleft lip nasal deformity

    Directory of Open Access Journals (Sweden)

    Singh Arun

    2009-01-01

    Full Text Available Bilateral cleft lip nose deformity is a multi-factorial and complex deformity which tends to aggravate with growth of the child, if not attended surgically. The goals of primary bilateral cleft lip nose surgery are, closure of the nasal floor and sill, lengthening of the columella, repositioning of the alar base, achieving nasal tip projection, repositioning of the lower lateral cartilages, and reorienting the nares from horizontal to oblique position. The multiplicity of procedures in the literature for correction of this deformity alludes to the fact that no single procedure is entirely effective. The timing for surgical intervention and its extent varies considerably. Early surgery on cartilage may adversely affect growth and development; at the same time, allowing the cartilage to grow in an abnormal position and contributing to aggravation of deformity. Some surgeons advocate correction of deformity at an early age. However, others like the cartilages to grow and mature before going in for surgery. With peer pressure also becoming an important consideration during the teens, the current trend is towards early intervention. There is no unanimity in the extent of nasal dissection to be done at the time of primary lip repair. While many perform limited nasal dissection for the fear of growth retardation, others opt for full cartilage correction at the time of primary surgery itself. The value of naso-alveolar moulding (NAM too is not universally accepted and has now more opponents than proponents. Also most centres in the developing world have neither the personnel nor the facilities for the same. The secondary cleft nasal deformity is variable and is affected by the extent of the original abnormality, any prior surgeries performed and alteration due to nasal growth. This article reviews the currently popular methods for correction of nasal deformity associated with bilateral cleft lip, it′s management both at the time of cleft lip repair

  1. Theodore von Karman

    Science.gov (United States)

    1950-01-01

    Dr. Theodore von Karman, co-founder of the Jet Propulsion Laboratory (JPL) Pasadena, California was an aeronautical theoretician. His contributions in the fields of aerodynamics and aeronautical engineering are well documented and well known to every aerospace engineer. He was the first winner of the prestigious U.S. Medal of Science presented to him by President John F. Kennedy. As well as being co-founder of JPL, he also was principal founder of a major rocket propulsion firm (Aerojet-General Corp.), the top science advisor to the U.S. Air Force during its transition to jet propulsion aircraft and the top science advisor to NATO. He was, during much of this time, the fountainhead of aerodynamic thought as head of the Guggenheim Aeronautical Laboratory at the California Institute of Technology (GALCIT) in Pasadena, California. In the May 1956 issue of the Journal of Aeronautical Sciences, it was said of him that 'No other man has had so great an impact on the development of aeronautical science in this country. Hundreds of young men became his students and scientific collaborators and were inspired to greater effort.' Dr. William H. Pickering, then director of JPL said in 1960 'We wouldn't have an aeronautical science as we know it today, if it weren't for Dr. Thoedore von Karman.' Under his guidance, Caltech's 10 foot wind tunnel was designed, built and operated. Industry firms such as Douglas, Northrop, Hughes, Lockheed, North American, Vultee and Consolidated all tested new aeronautical designs and concepts in GALCIT's tunnel. Even Boeing's own high-speed wind tunnel was heavily influenced by suggestions from von Karman. The National Advisory Committee for Aeronautics (NACA) became so concerned about GALCIT's growing influence over West coast aviation, it erected the Ames Laboratory in Sunnyvale, California in part to deter an ever widening aeronautical gap that had formed between NACA and GALCIT. From 1936 to 1940, Caltech stood alone as the only university

  2. Monitoring of stress relaxation and defect formation in metamorphic III-V semiconductor heterostructures for high-efficiency solar cells; Kontrolle von Spannungsrelaxation und Defektbildung in metamorphen III-V Halbleiterheterostrukturen fuer hocheffiziente Solarzellen

    Energy Technology Data Exchange (ETDEWEB)

    Schoene, Jan

    2009-07-21

    The paper discusses the further development of monolithic III-V multiple solar cells with three pn transitions for applications in concentrating PV systems. These triple solar cells consist of a GaInP upper cell, a GaInAs middle cell and a germanium lower cell, which are connected via electrically conducting and optically transparent tunnel diodes. Efficiencies are higher than 40 % with concentrated light. Demands on materials for III-V high-efficiency solar cells are extremely high. Especially in the metamorphic triple solar cell, for which compound semiconductors with different interatomic distances are deposited epitactically on each other, crystal defects may occur that impair the performance of the solar cell. The use of appropriate layer growing concepts may manipulate the formation of crystal defects and minimize their influence on solar cell performance. Both conventional and high-resolution transmission electron microscopy (TEM and HRTEM) as well as high-resolution X-ray diffraction (HRXRD) were applied successfully for investigating defect formation and layer stresses. In the investigations described, these methods were applied to develop a high-efficiency triple solar cell with a world first efficiency of 41.1 percent in concentrated light. [German] Diese Arbeit beschaeftigt sich mit der Weiterentwicklung von monolithischen III-V-Mehrfach-Solarzellen mit drei pn-Uebergaengen fuer die Anwendung in konzentrierenden Photovoltaiksystemen. Diese Tripelsolarzellen bestehen aus einer GaInP-Oberzelle, einer GaInAs-Mittelzelle und einer Germanium-Unterzelle, die mittels elektrisch leitender und optisch transparenter Tunneldioden verbunden sind. Derartige Solarzellen erzielen mittlerweile Rekordwirkungsgrade von mehr als 40 % unter konzentriertem Licht. Bei den III-V Hocheffizienzsolarzellen sind die Anforderungen an die Materialqualitaet ausserordentlich hoch. Insbesondere bei der metamorphen Tripelsolarzelle, bei der Verbindungshalbleiter mit unterschiedlichen

  3. Acquired von Willebrand Syndrome

    Institute of Scientific and Technical Information of China (English)

    郭涛

    2005-01-01

    @@ Acquired von Willebrand syndrome (AvWS) is kind of bleeding disorder with laboratory findings similar to those in congenital yon Willebrand disease (vWD).AvWS doesn's have any personal or family history of bleeding, but is associated with certain diseases or abnormal conditions or drugs. Although AvWS is being stated as a rare disease, it has gained more and more attention during the past years. Not because of the severity of the disease, but it is more common than we thought and most patients don' t have a proper diagnosis.

  4. Struktur von ABCE1

    OpenAIRE

    Karcher, Annette

    2007-01-01

    ABCE1 ist ein Mitglied der ATP Binding Cassette (ABC) Superfamilie. ABC Proteine binden und hydrolysieren ATP und verändern dabei ihre Konformation. Dadurch können sie mechanochemische Arbeit leisten. Durch drei zusätzliche Domänen unterscheidet sich ABCE1 von allen bislang bekannten und charakterisierten Mitgliedern dieser Familie. Neben den ATP-bindenden Regionen enthält ABCE1 eine cysteinreiche, N-terminale Domäne, welche zwei Eisen-Schwefel-Cluster bindet. Diese Domäne hat hohe s...

  5. State of development and use of the georadar technique; Entwicklungsstand und Anwendung der Georadartechnik

    Energy Technology Data Exchange (ETDEWEB)

    Busch, C. [Ruhrgas AG, Dorsten (Germany); Kathage, A.F. [Ruhrgas AG, Dorsten (Germany)

    1996-10-01

    Georadar can be an important tool in the geophysical prospecting of lines considered for the laying of buried gas and water mains. But current devices as yet do not perform adequately because of the mostly very complex subsurface conditions. The Georadar Development Joint Venture, a task force of six German gas utilities and the American market leader in the georadar sector, has set itself the task of developing a new system specially for the prospecting of lines considered for the laying of mains. As field tests under real and artificial conditions of use show, definite progress has been made already during the first stage of the project with antenna and software development. (orig.) [Deutsch] Georadar kann ein wichtiges Werkzeug zur geophysikalischen Erkundung von Verlegetrassen fuer Gas- und Wasserleitungen sein. Die Leistungsfaehigkeit heutiger Geraete ist jedoch hierfuer wegen der zumeist sehr komplexen Verhaeltnisse im Strassenuntergrund noch nicht ausreichend. Das Georadar Development Joint Venture, eine Arbeitsgemeinschaft sechs deutscher Gasversorgungsunternehmen sowie des amerikanischen Marktfuehrers im Bereich Georadar, hat sich das Ziel gesetzt, ein neues System speziell fuer die Trassenerkundung zu entwickeln. Wie Feldtests unter realen und kuenstlichen Einsatzbedingungen zeigen, wurden durch die Antennen- und Software-Entwicklung in der ersten Projektphase bereits deutliche Fortschritte erzielt. (orig.)

  6. Fuel cells. Development, technology, application. 2. new rev. and enl. ed.; Brennstoffzellen. Entwicklung, Technologie, Anwendung

    Energy Technology Data Exchange (ETDEWEB)

    Ledjeff-Hey, K.; Mahlendorf, F.; Roes, J. [eds.

    2001-07-01

    The book reviews the state of the art of fuel cells: General aspects; State incentives for fuel cell projects; Alkaline fuel cells; Polymer membrane fuel cell systems; Direct methanol fuel cells; The Vaillant PEM fuel cell heater; Cogeneration systems with fuel cells - results of a 5-year trial of 200 kW PAFC systems; PAFC plants in Japan; The MTU direct fuel cell hot module (MCFC); Plant conceptions and economic efficiency of SOFC power plants; The Sulzer Hexis project: Low-capacity SOFC technology; Low-capacity fuel cell systems - portable applications and battery replacement. [German] Dieses Buch gibt einen Ueberblick ueber den aktuellen Stand der Brennstoffzellen. Die zwoelf Kapitel lauten wie folgt: Brennstoffzellen - ein Ueberblick; Foerderung der Brennstoffzellentechnik; Alkalische Brennstoffzellen; Polymermembran-Brennstoffzellen-Systeme; Direkt-Methanolbrennstoffzellen; Das Vaillant PEM-Brennstoffzellen-Heizgeraet; Kraft-Waerme-Kopplung mit Brennstoffzellen - Erfahrungen aus ein 5-jaehrigen Versuchsbetrieb mit 200 kW-PAFC-Anlagen; PAFC Plants in Japan; Das MTU Direkt-Brennstoffzellen Hot Module (MCFC); Anlagenkonzeptionen und Wirtschaftlichkeit von SOFC-Kraftwerken; Das Projekt Sulzer Hexis - SOFC-Technologie fuer kleine Leistungen; Brennstoffzellen im kleinen Leistungsbereich - portable Anwendungen und Batterieersatz.

  7. Schwannoma of the nasal septum

    Directory of Open Access Journals (Sweden)

    Abdullah Karatas

    2016-11-01

    Full Text Available Schwannomas are benign and slow growing tumors originating from the Schwann cells of peripheral nerve sheath. Schwannomas of sinonasal origin are rare (4% however septal schwannomas are much more rarer. We presented a 31 year old female patient. At physical examination a pale gray, smooth polypoid lesion obstructing the right nasal cavity was detected. Midfacial degloving and endoscopic approach were combined for surgical treatment. The tumor was originating from posteromedial area of the septal nasal cartilage, close to the bony cartilaginous junction. Postoperative histological examination of the specimen showed a benign tumoral growth consisting of spindle shaped cells and immunohistochemical staining of the tumor proved septal schwannoma.

  8. Aspiration of Nasopore nasal packing.

    Science.gov (United States)

    Smith, Jonathan; Reddy, Ekambar

    2017-10-04

    We present a case of postoperative Nasopore aspiration in an otherwise fit and well 11-year-old. An endoscopic adenoidectomy had been performed without incident and Nasopore packing placed into each nasal cavity. Immediately after extubation, there was marked hypoxia, tachypnoea and high clinical suspicion of pack aspiration. The patient returned to theatre for emergency rigid bronchoscopy and retrieval of nasal packing. © BMJ Publishing Group Ltd (unless otherwise stated in the text of the article) 2017. All rights reserved. No commercial use is permitted unless otherwise expressly granted.

  9. Does Post Septoplasty Nasal Packing Reduce Complications?

    Directory of Open Access Journals (Sweden)

    Bijan Naghibzadeh

    2011-01-01

    Full Text Available The main issues in nasal surgery are to stabilize the nose in the good position after surgery and preserve the cartilages and bones in the favorable situation and reduce the risk of deviation recurrence. Also it is necessary to avoid the synechia formation, nasal valve narrowing, hematoma and bleeding. Due to the above mentioned problems and in order to solve and minimize them nasal packing, nasal splint and nasal mold have been advised. Patients for whom the nasal packing used may faced to some problems like naso-pulmonary reflex, intractable pain, sleep disorder, post operation infection and very dangerous complication like toxic shock syndrome. We have two groups of patients and three surgeons (one of the surgeons used post operative nasal packing in his patients and the two others surgeons did not.Complications and morbidities were compared in these two groups. Comparing the two groups showed that the rate of complication and morbidities between these two groups were same and the differences were not valuable, except the pain and discomfort post operatively and at the time of its removal. Nasal packing has several risks for the patients while its effects are not studied. Septoplasty can be safely performed without postoperative nasal packing. Nasal packing had no main findings that compensated its usage. Septal suture is one of the procedures that can be used as alternative method to nasal packing. Therefore the nasal packing after septoplasty should be reserved for the patients with increased risk of bleeding.

  10. Nasal pulse oximetry overestimates oxygen saturation

    DEFF Research Database (Denmark)

    Rosenberg, J; Pedersen, M H

    1990-01-01

    Ten surgical patients were monitored with nasal and finger pulse oximetry (Nellcor N-200) for five study periods with alternating mouth and nasal breathing and switching of cables and sensors. Nasal pulse oximetry was found to overestimate arterial oxygen saturation by 4.7 (SD 1.4%) (bias...

  11. Investigations thermal-hygral suitability of vacuum insulation panels for reinstatement of buildings from the 19th century in Vienna; Untersuchungen zur thermisch-hygrischen Eignung von Vakuumdaemmplatten zur Sanierung von Gebaeuden der Wiener Gruenderzeit

    Energy Technology Data Exchange (ETDEWEB)

    Korjenic, A. [Technische Univ., Vienna (Austria). Abt. Bauphysik; Dreyer, J. [Technische Univ., Vienna (Austria). Inst. fuer Baustofflehre, Bauphysik und Brandschutz, Abt. Bauphysik

    2003-12-01

    The necessity for efficient, as well as room-saving insulation materials is felt especially in renovation projects with limited available space. With renovations in particular, the space is often either too expensive or simply not available to meet the current thermal insulation standards. With the vacuum insulation panels (VIP), an insulation product is now available with a high thermal insulation level in form of very thin panels. The application of the new vacuum insulation in old-building renovation as well as the effect on the heat- and moisture behaviour of built in components was examined and analyzed. The thermal-hygric behaviour of vacuum insulated walls, the effect of heat bridges and the influence of the climate data were investigated. As specific object for application of the vacuum insulation was chosen a typical Viennese ''Gruenderzeit''-house. (orig.) [German] In der Baupraxis existiert fuer die Gebaeudesanierung ein Bedarf nach effizienten Daemmaterialien, die nur einen geringen Platzbedarf haben. Der fuer Daemmungen zur Verfuegung stehende Raum wird fuer Nutzungszwecke benoetigt bzw. ist nicht vorhanden. Mit den seit einiger Zeit fuer den Baumarkt entwickelten Vakuumdaemmplatten steht nun ein Daemmstoff mit hohen Daemmeigenschaften in Form von sehr duennen Platten zur Verfuegung. Die Anwendung von Vakuumdaemmung im Sanierungsbereich und ihre Auswirkungen auf den Waerme- und Feuchtedurchgang in Bauteilen und das Raumklima wurden untersucht an mit Vakuumdaemmung sanierten typischen Gruenderzeitgebaeuden in Wien. (orig.)

  12. Changes in nasal resistance and nasal geometry using pressure and acoustic rhinometry in a feline model of nasal congestion

    DEFF Research Database (Denmark)

    McLeod, R.L.; Mingo, G.G.; Herczku, C.

    1999-01-01

    This is the first report describing the use and pharmacological characterization of nasal patency by both pressure rhinometry and acoustic rhinometry (AcR) in an experimental cat model of nasal congestion. In pressure rhinometry studies, aerosolized compound 48/80 (0.1-3.0%), a mast cell liberator...... histamine (0.1-1.0%) on nasal geometry were similar to compound 48/80. We conclude that the cat is a useful model for evaluating the pharmacological actions of potential nasal decongestants. Furthermore, we also conclude that AcR is a useful method for noninvasive assessment of nasal patency...

  13. Nasal intubation: A comprehensive review

    Directory of Open Access Journals (Sweden)

    Varun Chauhan

    2016-01-01

    Full Text Available Nasal intubation technique was first described in 1902 by Kuhn. The others pioneering the nasal intubation techniques were Macewen, Rosenberg, Meltzer and Auer, and Elsberg. It is the most common method used for giving anesthesia in oral surgeries as it provides a good field for surgeons to operate. The anatomy behind nasal intubation is necessary to know as it gives an idea about the pathway of the endotracheal tube and complications encountered during nasotracheal intubation. Various techniques can be used to intubate the patient by nasal route and all of them have their own associated complications which are discussed in this article. Various complications may arise while doing nasotracheal intubation but a thorough knowledge of the anatomy and physics behind the procedure can help reduce such complications and manage appropriately. It is important for an anesthesiologist to be well versed with the basics of nasotracheal intubation and advances in the techniques. A thorough knowledge of the anatomy and the advent of newer devices have abolished the negative effect of blindness of the procedure.

  14. Nasal continuous positive airway pressure

    DEFF Research Database (Denmark)

    Scholze, Alexandra; Lamwers, Stephanie; Tepel, Martin

    2012-01-01

    Obstructive sleep apnoea (OSA) is linked to increased cardiovascular risk. This risk can be reduced by nasal continuous positive airway pressure (nCPAP) treatment. As OSA is associated with an increase of several vasoconstrictive factors, we investigated whether nCPAP influences the digital volume...

  15. Diagnostic strategies in nasal congestion

    Directory of Open Access Journals (Sweden)

    John Krouse

    2010-02-01

    Full Text Available John Krouse1, Valerie Lund2, Wytske Fokkens3, Eli O Meltzer41Temple University School of Medicine, Philadelphia, PA, USA; 2Ear Institute, University College London, UK; 3Department of Otorhinolaryngology, Amsterdam Medical Centre, Netherlands; 4Allergy and Asthma Medical Group and Research Center, San Diego, CA and Department of Pediatrics, University of California, San Diego, USAAbstract: Nasal congestion is a major symptom of upper respiratory tract disorders, and its characterization an important part of the diagnosis of these illnesses. Patient history and assessment of nasal symptoms are essential components of diagnosis, providing an initial evaluation that may be adequate to rule out serious conditions. However, current congestion medications are not always fully effective. Thus, if symptoms do not respond adequately to therapy, or symptoms suggestive of more serious conditions are present, specialized assessments may be needed. Various techniques are available for diagnosing patients, including those used chiefly by primary care clinicians and those requiring the expertise of otolaryngologists, allergists, and other specialists. Endoscopy remains a mainstay for evaluating nasal blockage and its causes, while modalities such as peak nasal inspiratory flow and acoustic rhinometry are evolving to provide easy-to-use, noninvasive procedures that are sensitive enough to measure small but clinically important abnormalities and therapeutic changes. Several imaging modalities are available to the specialist for severe or unusual cases, as are specialized diagnostic procedures that measure adjunctive features of congestion, such as impaired mucociliary function.Keywords: allergic rhinitis, congestion, diagnosis, obstruction, rhinosinusitis

  16. Nasal Schwannoma: a case report

    Directory of Open Access Journals (Sweden)

    Siu-Navarro YJ, Pérez-Carbajal AJ

    2013-10-01

    Full Text Available Introduction: Schwannomas are benign tumors that arise from Schwann cells peripheral nerves sheath. About 25-45% occur in the head and neck and only 4% of these tumors involve the sinunasal tract.Objective: To provide, through a clinic case and lecture review, the clinical and radiopatology findings of a bening and unusual tumors, as are the Nasal schwannomas. Case Report: We report a case of a young woman with nasal schwannoma, who complain of left nasal obstruction and rhinorrhea, which after subsequent imaging studies, surgical and pathology analisis, diagnosis was found. Sustained a favorable clinical evolution.Results and Discussion: The clinic and radiologic findings are nonspecific, depend upon the location or size of the tumor and subsequent involvement of surrounding structures, but generally present as a mass with less agressive behavior. The elective treatment is surgery, confirming this disease by microscopic and immunohistochemistry studies.Conclusion: Given these aspects must be considered nasal schwannomas within the differential diagnosis of a tumor with less aggressive behavior, clinical-radiological, because implies good results for the patient and unusual recurrence after surgery.

  17. Immunophenotype Heterogeneity in Nasal Glomangiopericytoma

    Directory of Open Access Journals (Sweden)

    Adriana Handra-Luca

    2015-01-01

    Full Text Available Nasal glomangiopericytoma is rare. The immunophenotype is heterogeneous, more frequently smooth-muscle-actin and CD34-positive. We report expression patterns for several vascular-related proteins such as CD99, CD146, Bcl2, and WT1 as well as for treatment-related proteins such as mTOR and EGFR in a nasal glomangiopericytoma. The patient (woman, 86 years presented with a left nasal tumefaction. The resected specimen (1.5-cm showed a glomangiopericytoma. Tumor cells expressed smooth-muscle-actin, CD31, CD34, and progesterone receptor. They also expressed the vascular-cell-related proteins Bcl2, CD99, CD146, and WT1, as well as mTOR and EGFR. Nasal glomangiopericytomas show immunohistochemical heterogeneity for vascular-related markers, suggesting a possible extensive pericytic differentiation. The expression of potential targets for drug treatments such as mTOR and EGFR may impact on the clinical follow-up of these tumors occurring at advanced ages, which may require complex surgery.

  18. Experimental and theoretical investigations for optimizing the electric ignition of natural gas fuelled industrial burners; Experimentelle und theoretische Untersuchungen zur Optimierung der elektrischen Zuendung von erdgasbetriebenen Industriebrennern

    Energy Technology Data Exchange (ETDEWEB)

    Koesters, M.; Scherello, A.; Flamme, M.; Kremer, H.

    2001-07-01

    The effects of the key flow, mixing and ignition parameters on the ignition process was investigated in near-practical conditions. It was found that the ignition energy can be minimized by careful selection of the electrode configuration and positioning near the burner. Further, a criterion was developed for developing characteristic fields and design specifications for gas burners. The FLUENT code can calculate the mixing, flow and turbulence situation of a burner. This, and plus the newly established ignition criterion, can support the development of characteristic fields and help to minimize the experimental expenditure. [German] Der Einfluss der wichtigsten Stroemungs-, Mischungs- und Zuendparameter auf die Zuendung wurde mit Hilfe gezielter experimenteller und theoretischer Untersuchungen unter industrienahen Bedingungen getestet. Hierbei konnte eine gute Uebereinstimmung zwischen den Messungen und Rechnungen erzielt werden. Die Ergebnisse haben gezeigt, dass durch eine geeignete Wahl der Elektrodenkonfiguration und der Elektrodenpositionierung im Brennernahbereich eine Zuendenergieminimierung erreicht werden kann. Gleichzeitig wurde ein Kriterium entwickelt, das zur Erarbeitung von Kennfeldern und Auslegungsvorschriften fuer Gasbrenner genutzt werden kann. Mit Hilfe des kommerziellen CFD-Programms FLUENT kann die Mischungs-, Stroemungs- und Turbulenzsituation eines Brenners numerisch berechnet werden. Mittels dieser Ergebnisse und unter Anwendung des ermittelten Zuendkriteriums kann die Erstellung von Arbeits- und Zuendkennfeldern fuer die Neuentwicklung bzw. Verbesserung von Industriegasbrennern unterstuetzt und somit der experimentelle Aufwand minimiert werden. (orig.)

  19. Licence to Mine? Ein Überblick über Rahmenbedingungen von Text and Data Mining und den aktuellen Stand der Diskussion

    Directory of Open Access Journals (Sweden)

    Christian Winterhalter

    2016-11-01

    Full Text Available Der Artikel gibt einen Überblick über die Möglichkeiten der Anwendung von Text and Data Mining (TDM und ähnlichen Verfahren auf der Grundlage bestehender Regelungen in Lizenzverträgen zu kostenpflichtigen elektronischen Ressourcen, die Debatte über zusätzliche Lizenzen für TDM am Beispiel von Elseviers TDM Policy und den Stand der Diskussion über die Einführung von Schrankenregelungen im Urheberrecht für TDM zu nichtkommerziellen wissenschaftlichen Zwecken. The article gives a survey about the potential application of text and data mining (TDM or similar techniques on the basis of given licence agreements for subscription-based electronic resources. It also resumes the debate about the supplemental licence amendments for TDM that has arisen over the introduction of Elsevier’s TDM Policy. Finally, it describes the current discussions about the possible implementation of copyright exemptions for TDM within the context of non-commercial scientific research.

  20. Nasal Septum Perforation due to Methamphetamine abuse

    Directory of Open Access Journals (Sweden)

    Mehdi Bakhshaee

    2012-07-01

    Full Text Available Introduction: Spontaneous Perforation of the nasal septum is an uncommon condition. Nasal inhalation of substances such as cocaine has long been linked to this Perforation. Case Report: This report describes the case of a 46-year-old woman who was addicted to methamphetamine and who presented with perforation of the nasal septum.This is the first reported case of nasal septal necrosis linked to nasal inhalation of methamphetamine. Conclusions: Patient history and assurance regardingillegal drug consumption and abuse is a key point for fast and accurate diagnosis. The pathophysiology of drug-induced sinunasal disease and a review of the literature are also presented.

  1. Alejandro Von Humboldt

    Directory of Open Access Journals (Sweden)

    Gerardo Paz Otero

    1965-09-01

    Full Text Available Diverso fue y sigue siéndolo, el destino de los dos hermanos Humboldt, Guillermo y Alejandro. Sino que se inicia con el nacimiento: Guillermo, el mayor, nace el 22 de junio de 1767 en Potsdam, residencia de los emperadores prusianos, la ciudad de los palacios imperiales, el imperio del militarismo germano; su cuna se meció cerca al palacete de Sans-Soussi, donde Federico el Grande forja ba el poderío de Prusia, cultivaba las ciencias y las artes, anfitrionaba a los intelectuales de Europa, y era "vasallo espiritual de Volta ire", según la aguda frase de Goethe. Alejandro viene al mundo dos años después (14 de septiembre de 1769 en Berlín, en la casa burguesa de la Jagerstrasse (calle del cazador que su madre Elizabeth von Humboldt heredara de su primer esposo.

  2. Mikrochirurgische Entfernung von Hirnstammkavernomen

    Directory of Open Access Journals (Sweden)

    Pfisterer W

    2002-01-01

    Full Text Available Der Anteil der Kavernome an allen intrakraniellen vaskulären Malformationen beträgt 14 %. Davon liegen etwa 20 % im Hirnstamm. Bei einer Rezidivblutungsrate von 21 % jährlich ist auch eine Exstirpation im Hirnstamm indiziert. Wir berichten über 3 Patienten mit Hirnstammkavernomen, die in mikrochirurgischer Technik bei geringer Morbidität und ohne Mortalität an unserer Abteilung total exstirpiert wurden. Wir halten die subakute Phase für den besten Zeitpunkt zur Entfernung des Kavernoms, wenn dies der klinisch-neurologische Zustand des Patienten erlaubt. Die mikrochirurgische Exstirpation wurde durch Elektrophysiologie (akustisch und somatosensorisch evozierte Potentiale, Endoskopie und Neuronavigation unterstützt.

  3. Appraisal of transverse nasal groove: A study

    Directory of Open Access Journals (Sweden)

    Belagola D Sathyanarayana

    2012-01-01

    Full Text Available Background: Transverse nasal groove is a condition of cosmetic concern which awaits due recognition and has been widely described as a shallow groove that extends transversely over the dorsum of nose. However, we observed variations in the clinical presentations of this entity, hitherto undescribed in literature. Aims: We conducted a clinicoepidemiological study of transverse nasal lesions in patients attending our outpatient department. Methods: We conducted a prospective observational study. We screened all patients attending our out-patient department for presence of transverse nasal lesions, signs of any dermatosis and associated other skin conditions. Results: One hundred patients were recruited in the study. Females (80% predominated over males. Most patients were of 15-45 years age group (70%. Majority of the transverse nasal lesions were classical transverse nasal groove (39% and others included transverse nasal line (28%, strip (28%, ridge (4% and loop (1%. Seborrhoeic diathesis was the most common condition associated with transverse nasal lesion. Conclusions: Occurrence of transverse nasal line, strip, ridge and loop, in addition to classical transverse nasal groove implies that latter is actually a subset of transverse nasal lesions. Common association of this entity with seborrheic dermatitis, seborrhea and dandruff raises a possibility of whether transverse nasal lesion is a manifestation of seborrheic diathesis.

  4. A simple nasal anemometer for clinical purposes.

    Science.gov (United States)

    Hutters, B; Brøndsted, K

    1992-01-01

    There is a need for clinical methods which give more direct information about the behaviour of the velopharyngeal mechanism in natural speech than do the examination methods normally applied to patients suffering from velopharyngeal insufficiency. One possibility is the recording of nasal airflow in order to detect nasal emission of air. The purpose of the present study is to examine the qualities and the characteristics of a simple and cheap nasal anemometer. As this type of flowmeter is considered less reliable than most other flowmeters, its limitations must be clearly understood and accounted for in drawing conclusions. Therefore, nasal airflow in speech obtained with this flowmeter is discussed in relation to nasal airflow obtained by the more reliable pneumotachograph and in relation to nasal airflow data found in the literature. The tests made here suggest that, at least for the type of speech material and measurements used in the present study, reliable nasal airflow data can be obtained by the anemometer.

  5. Tierexperimentelle Untersuchungen zur Effektivit(a)t der transarteriellen Chemoembolisation (TACE) unter Einsatz von Bletilla striata

    Institute of Scientific and Technical Information of China (English)

    QIAN Jun; Vossoughi Daryusch; Maataoui Adel; Oppermann Elsiez; Bechstein Wolf; Vogl Thomas Josef

    2005-01-01

    Evaluierung der Effektivit(a)t von Bletilla striata bei transerteriellenChemoembo lisation (TACE) im Kleintiermodell. Nach subkapsul(a)rer Implantation (Tag 0) eines soliden Morris Hepatoms (2 mm3) bei ACI-Ratten (n = 30) wurden am 13. Tag die Tumorvolumina (V1) magnettomographisch bestimmt. Im Anschlu erfolgten nach Laparatomie die retrograde Katheterisierung der Arteria gastroduodenalis und die Anwendung folgender Therapieprotokolle: (A) TACE (0,1 mg MitomycinC + 0,1 mL Lipiodol) + Bletilla striata (1,0 mg) (n=10); (B) TACE (Bletilla striata (1,0 mg) + Ligatur (n=10); (C) TACE allein (Kontrollgruppe, n=10). Zur Effektivit(a)tsbeurteilung der unterschiedlichen Therapieprotokolle erfolgte am 28. Tag eine erneute magnettomographische Bestimmung der Tumorvolumina (V2). Das durchschnittliche Tumorvolumen der Gruppen A, Bund C vor und nach interventioneller Therapie betrug 0,0355 cm3 und 0,2248 cm3 , 0,0374 cm3 und 0,0573 cm3 sowie 0,0380 cm3 und 0,3674 cm3. Das errechnete durchschnittliche Verh(a)ltnis (V2/V1) betrug 6,28, 1,53 sowie 9,14. Im Vergleich zur Kontrollgruppe C Beobachtungszeitraum ermittelt werden, wahrend zwischen Gruppe A und Gruppe C keine statistisch signifikanten (P>0,05) Unterschiede im Tumorwachstum festgestellt werden konnten. Das Wachstum der induzierten Lebertumoren konnte unter Behandlung mittels TACE + Bletilla striata + Ligatur im Tiermodell statistisch signifikant im Vergleich zur Kontrollgruppe gehemmt werden.

  6. von Willebrand Disease (For Parents)

    Science.gov (United States)

    ... to classify the type of von Willebrand disease platelet function tests, which determine how well the platelets work ... for pain or fever. These drugs interfere with platelet function and can increase the risk of bleeding. It ...

  7. Kleben von Kunststoff mit Metall

    CERN Document Server

    Brockmann, W; Käufer, H

    1989-01-01

    Das Buch behandelt das Kleben von Kunststoffen mit Metallen in einer fur den Praktiker verstandlichen und umsetzbaren Form. Es leitet zu Klebeverfahren an, die optimale Ergebnisse hinsichtlich Qualitat, Dauerhaftigkeit und Wirtschaftlichkeit liefern.

  8. Planung und Bewertung von Montagesystemen

    Science.gov (United States)

    Hartel, Marko; Lotter, Bruno

    Die Gestaltung von Montagesystemen ist eine wesentliche Aufgabenstellung an die planenden Bereiche eines Unternehmens. Anhand von Praxis-beispielen werden Planungssystematiken and Bewertungsverfahren — sei es fur die Effizienzsteigerung einer bestehenden Montage oder die Entscheidung zwischen Varianten eines geplanten Montagesystems — aufzeigt. Die folgende Planungssystematik nach REFA wird für Produktionssysteme im Allgemeinen angewandt; die Planungssystematik nach Lotter ist speziell auf Montagesysteme ausgelegt.

  9. Theorie und Praxis von Hochschulrankings

    OpenAIRE

    Hornbostel, Stefan

    2007-01-01

    Der Beitrag gibt einen Überblick über die theoretische Grundlage von Hochschulrankings, welche in der qualitativ stark differenzierten Hochschullandschaft in Deutschland entscheidend für öffentliche Reputationsurteile sein können. Ausgehend von einem formal gleichrangigen Institutionengefüge der Hochschullandschaft in Deutschland haben die Stichworte Profilbildung, Exzellenz und Wettbewerb in den letzten Jahren zunehmend an Bedeutung gewonnen. Der daraus resultierende große Informationsbedarf...

  10. Smart polymers in nasal drug delivery

    Directory of Open Access Journals (Sweden)

    Ankita Chonkar

    2015-01-01

    Full Text Available Nasal drug delivery has now been recognized as a promising route for drug delivery due to its capability of transporting a drug to systemic circulation and central nervous system. Though nasal mucosa offers improved bioavailability and quick onset of action of the drug, main disadvantage associated with nasal drug delivery is mucocilliary clearance due to which drug particles get cleared from the nose before complete absorption through nasal mucosa. Therefore, mucoadhesive polymeric approach can be successfully used to enhance the retention of the drug on nasal mucosal surface. Here, some of the aspects of the stimuli responsive polymers have been discussed which possess liquid state at the room temperature and in response to nasal temperature, pH and ions present in mucous, can undergo in situ gelation in nasal cavity. In this review, several temperature responsive, pH responsive and ion responsive polymers used in nasal delivery, their gelling mechanisms have been discussed. Smart polymers not only able to enhance the retention of the drug in nasal cavity but also provide controlled release, ease of administration, enhanced permeation of the drug and protection of the drug from mucosal enzymes. Thus smart polymeric approach can be effectively used for nasal delivery of peptide drugs, central nervous system dugs and hormones.

  11. Nasal Outcomes of Presurgical Nasal Molding in Complete Unilateral Cleft Lip and Palate

    Directory of Open Access Journals (Sweden)

    Emily M. Williams

    2012-01-01

    Full Text Available Objective. Short-term nasal forms following primary lip repair were compared between presurgical nasal molding and control groups. Aim. To compare nasal symmetry between patients that had nasal molding and lip repair with those that had only lip repair. Design. Retrospective case-control study Patients. Complete unilateral CL+P patients had basilar and frontal photographs at two time points: (1 initial (2 postsurgical. 28 nasal molding patients and 14 control patients were included. Intervention. Presurgical nasal molding was performed prior to primary lip repair in intervention group. No nasal molding was performed in control group. Hypothesis. Nasal molding combined with lip surgery repair according to the Millard procedure provides superior nasal symmetry than surgery alone for nostril height-width ratios and alar groove ratios. Statistics. Shapiro-Wilk test of normality and Student’s -tests. Results. A statistically significant difference was found for postsurgical nostril height-width ratio (<.05. No other statistically significant differences were found. Conclusions. Nasal molding and surgery resulted in more symmetrical nostril height-width ratios than surgery alone. Alar groove ratios were not statistically significantly different between groups perhaps because application of nasal molding was not early enough; postsurgical nasal splints were not utilized; overcorrection was not performed for nasal molding.

  12. Models for settlement prediction of structures in opencast dumps; Modelle zur Setzungsprognose von Bauwerken auf Tagebaukippen

    Energy Technology Data Exchange (ETDEWEB)

    Birle, E.; Vogt, S. [Technische Univ. Muenchen (Germany). Zentrum Geotechnik

    2016-05-01

    Strassendammes, koennen die in den Kippenuntergrund eingetragenen Zusatzspannungen zu einer Erhoehung der Verformungsgeschwindigkeiten gegenueber den Kippeneigensetzungen fuehren. Einfache ein-dimensionale phaenomenologische Kriechmodelle sind in diesem Fall nicht in der Lage, das damit verbundene Verformungsverhalten der Kippenboeden zu beschreiben, da die Abhaengigkeit der Verformungsrate vom eingepraegten Spannungszustand nicht abgebildet wird. Stattdessen koennen, wie im Beitrag erlaeutert wird, visko-elastoplastische Stoffmodelle herangezogen werden, mit denen die sich einstellenden Kippensetzungen zutreffend beschrieben werden koennen. Voraussetzung zur Anwendung der Stoffmodelle ist aber eine Kalibrierung der Stoffmodellparameter fuer die betrachtete Kippenrandbedingung anhand von Setzungsmessungen.

  13. Development and application of methods and models for the calculation of spatially and temporally highly resolved emissions in Europe; Entwicklung und Anwendung von Methoden und Modellen zur Berechnung von raeumlich und zeitlich hochaufgeloesten Emissionen in Europa

    Energy Technology Data Exchange (ETDEWEB)

    Thiruchittampalam, Balendra

    2014-04-08

    High spatial and temporal resolution models are essential for answering many questions of air quality management and climate modeling. High-resolution emission models are required to determine the concentration of pollutants using chemical transport models, and to quantify the impacts on health and environment and in particular to develop adequate countermeasures. The aim of this work is to develop methods for the calculation of spatially and temporally high-resolved emissions and to apply these exemplarily on a 1 km x 1 km and hourly resolution for the year 2008 in the EU-27 and EFTA countries. The derivation of methods for the spatial and temporal resolution of emissions with corresponding detailed equations is one of the major improvements that have been carried out in the course of this work. The improvement of the spatial distribution of emissions from the point source relevant sectors like energy supply, industry and waste management is achieved by considering sector specific diffuse emission shares. The progress of the spatial distribution of emissions from households is in particular the development of a fuel type weighted distribution over Europe. Another main focus is the development of the spatial distribution of road transport emissions. Due to the restricted access to traffic count data at the European level, methods have been established to provide reliable emissions on grid level for Europe. The progress in the spatial distribution of agricultural emissions is achieved by the consideration of diffuse shares similar to the other point source relevant sectors like energy supply or industry. In addition to the spatial distribution of the emissions the temporal resolution is a main focus of this work, since the state of knowledge of the temporal resolution of emissions in Europe is still rudimentary. Therefore, it was necessary to develop in particular time curves for the hourly resolution of emissions for the main sectors, namely electricity and heat supply, households, commercial, trade and services, road transport and agriculture. One of the main focuses of the development of temporal profiles was specifically to consider temperature data and other parameters. The derivation of the time profiles requires huge amount of indicator data for each time step. Consequently, the goal for the development of temporal profiles in Europe is to derive temperature dependent equations which are capable of generating sector specific profiles for the present as well as for the future. Based on the developed methods, for the first time the visualization of hourly emissions on a 5 km x 5 km for Europe could be shown. The basis for the visualization was the calculation of hourly emissions at a 1 km x 1 km resolution. Due to the lack of quantitative uncertainty assessments, it was necessary to identify the reasons for the lack of uncertainty analysis at the European level and also to describe the possibilities of a quantitative uncertainty analysis for high resolution emission models. Moreover, on the basis of examples it was possible to describe, how the spatial and temporal uncertainty analysis of high resolution emission models can be carried out.

  14. Unusual Postrhinoplasty Complication: Nasal Dorsum Cyst

    Directory of Open Access Journals (Sweden)

    Pier Giorgio Giacomini

    2014-01-01

    Full Text Available Among all the possible complications of aesthetic rhinoplasty, a rare one is the development of cystic masses on the nasal dorsum: several theories suggest that cysts develop commonly by entrapment of nasal mucosa in the subcutaneous space, but they can also originate from foreign body reactions. This report deals with two cases of nasal dorsum cysts with different pathogenesis: both patients had undergone aesthetic rhinoplasty in the past (26 years ago and 14 years ago, resp.. Both cystic masses were removed via a direct open approach and nasal reconstruction was performed successfully with autologous vomer bone. The pathologic investigations showed a foreign body inclusion cyst associated with latex rubber in the first case and a sequestration of a mucosal-lined nasal bone was not removed at the time of primary rhinoplasty in the second case. A brief review of the literature focuses on the pathophysiology and treatment options for nasal dorsal cysts following aesthetic rhinoplasty.

  15. Post septorhinoplasty custom-made unilateral nasal stent for nasal cleft deformity

    Directory of Open Access Journals (Sweden)

    Manu Rathee

    2015-01-01

    Full Text Available Context: Nasal cleft deformity is a complicated problem. Utilization of nasal stent in post septorhinoplastyaims at establishing and maintaining airway patency, tissue position, and reduces tissue contracture after surgery. Case Report: A 16-year-old female patient presented with history of surgical reconstruction of congenital cleft lip and cleft palate with secondary septorhinoplasty of nasal cleft deformity. Patient was referred for nasal stent 1 week after septorhinoplasty. This case report provides a novel technique for fabrication of esthetic nasal stent after postseptorhinoplasty for secondary cleft nose deformity correction. Conclusion: This case report presents a simple, convenient technique for nasal stent fabrication for prevention of restenosis for cleft nose deformity post secondary septorhinoplasty. Provision of nasal stent allows breathing, maintains esthetics, comfort, nasal patency, and contour with minimal discomfort.

  16. Post septorhinoplasty custom-made unilateral nasal stent for nasal cleft deformity

    OpenAIRE

    Manu Rathee; Mohaneesh Bhoria; Priyanka Boora

    2015-01-01

    Context: Nasal cleft deformity is a complicated problem. Utilization of nasal stent in post septorhinoplastyaims at establishing and maintaining airway patency, tissue position, and reduces tissue contracture after surgery. Case Report: A 16-year-old female patient presented with history of surgical reconstruction of congenital cleft lip and cleft palate with secondary septorhinoplasty of nasal cleft deformity. Patient was referred for nasal stent 1 week after septorhinoplasty. This case repo...

  17. IgG4-Related Nasal Pseudotumor

    Directory of Open Access Journals (Sweden)

    L. K. Døsen

    2015-01-01

    Full Text Available IgG4-related disease is recognized as one form of autoimmune pancreatitis. During the last ten years, it has also been described in several other organs. We present two patients with lesions showing a histological picture of fibrosis and lymphoplasmacytic infiltrations with abundant IgG4 positive plasma cells at hitherto unreported symmetrical nasal locations. The symmetrical complex consisted of one central lesion in the anterior nasal septum and the two others in each of the lateral nasal walls. The lesions extended from the anterior part of the inferior concha into the vestibulum and caused severe nasal obstruction.

  18. Nasal Myiasis in Hinduism and Contemporary Otorhinolaryngology.

    Science.gov (United States)

    Bosmia, Anand N; Zimmermann, Terence M; Griessenauer, Christoph J; Shane Tubbs, R; Rosenthal, Eben L

    2017-08-01

    Various case reports on nasal myiasis written during the 1990s and 2000s state that nasal myiasis, which is known as peenash among South Asian natives, is a form of divine punishment in Hindu mythology, but do not provide citations from Hindu scriptures that would suggest this interpretation. This paper aims to discuss the phenomenon of peenash in a historical context by examining medical literature written during the nineteenth and early twentieth centuries, to identify Hindu texts contributing to the belief of some Hindus that nasal myiasis is a form of divine punishment, and to provide an overview of contemporary treatment for and management of nasal myiasis.

  19. Nasal and Oral Consonant Similarity in Speech Errors: Exploring Parallels with Nasal Consonant Harmony

    Science.gov (United States)

    Walker, Rachel

    2007-01-01

    Previous research has found that "similar" sounds interact in phonological nasal consonant harmony, wherein certain consonants become nasals when the word contains a nasal (e.g., Kikongo: /-kun-idi/ [right arrow] [-kun-ini] "planted"). Across languages, stops and approximants are chiefly affected, especially voiced consonants and ones that match…

  20. Perception of Better Nasal Patency Correlates with Increased Mucosal Cooling after Surgery for Nasal Obstruction

    Science.gov (United States)

    Garcia, Guilherme; Sullivan, Corbin; Frank-Ito, Dennis; Kimbell, Julia; Rhee, John

    2014-11-01

    Nasal airway obstruction (NAO) is a common health problem with 340,000 patients undergoing surgery annually in the United States. Traditionally, otolaryngologists have focused on airspace cross-sectional areas and nasal resistance to airflow as objective measures of nasal patency, but neither of these variables correlated consistently with patients' symptoms. Given that the sensation of nasal airflow is also associated with mucosal cooling (i.e., heat loss) during inspiration, we investigated the correlation between the sensation of nasal obstruction and mucosal cooling in 10 patients before and after NAO surgery. Three-dimensional models of the nasal anatomy were created based on pre- and post-surgery computed tomography scans. Computational fluid dynamics (CFD) simulations were conducted to quantify nasal resistance and mucosal cooling. Patient-reported symptoms were measured by a visual analog scale and the Nasal Obstruction Symptom Evaluation (NOSE), a disease-specific quality of life questionnaire. Our results revealed that the subjective sensation of nasal obstruction correlated with both nasal resistance and heat loss, but the strongest correlation was between the NOSE score and the nasal surface area where heat flux exceeds 50 W /m2 . In conclusion, a significant post-operative increase in mucosal cooling correlates well with patients' perception of better nasal patency after NAO surgery.

  1. Evaluation of the state of the art in application and utilisation of PSAs for regulatory decision making worldwide; Auswertung des aktuellen internationalen Standes der Anwendung probabilistischer Sicherheitsanalysen bei regulatorischen Entscheidungen

    Energy Technology Data Exchange (ETDEWEB)

    Kafka, P.

    2000-09-01

    Bereich der Sicherheitstechnik und insbesondere auf dem Gebiet der PSA im Hinblick auf regulatorische Entscheidungen. Einbezogen sind dabei sowohl die Aktivitaeten im Bereich der Kerntechnik als auch auf nichtnuklearen Gebieten bzw. Technologien. Diese Untersuchungen dienen vor allem dazu, den Stand der risiko-orientierten Betrachtung zu verfolgen und daraus Schlussfolgerungen fuer eine sinnvolle Weiterentwicklung und Beurteilung der Sicherheitstechnik fuer kerntechnische Einrichtungen in der Bundesrepublik Deutschland abzuleiten. Im einzelnen sind im Bericht sowohl technologie-bezogene als auch fachthemen-bezogene Untersuchungen dargestellt und bewertet. Als wesentliche Bewertung kann man zusammenfassen, dass der Wissensstand zu und die Anwendung von risiko-orientierten Betrachtungen fuer regulatorische Entscheidungen stetig zunimmt. Dies gilt sowohl im Bereich der Kerntechnik als auch in nicht-nuklearen Technologien. Der Trend geht zu quantitativen Analysen und Bewertungen, wobei die Fragen zur Aussagesicherheit der Ergebnisse und zur Verwendbarkeit wahrscheinlichkeits-orientierter (probabilistischer) Sicherheitsbewertungen im legislativen und exekutiven Bereich mit der erforderlichen Sorgfalt behandelt werden. Die Weiterentwicklung zur Anwendungsreife der risiko-orientierten Sicherheitsbetrachtung findet vorwiegend im Ausland statt. Aus diesem Grunde ist die Beachtung und Auswertung der internationalen Entwicklungen auf diesem Gebiet von besonderer Bedeutung. In der Bundesrepublik Deutschland wurden unter Beachtung dieser internationalen Aktivitaeten dazu ebenfalls wertvolle Entwicklungsschritte geleistet. (orig.)

  2. Vergleich von simulierten und reellen Schleppkurven von Landmaschinen

    Directory of Open Access Journals (Sweden)

    Steffen Hürter

    2014-02-01

    Full Text Available An das landwirtschaftliche Wegenetz werden durch die kontinuierliche Größenentwicklung von Landmaschinen neue Anforderungen gestellt. Die Maschinen werden breiter und länger und besitzen mehr Achsen und komplexere Lenksysteme als in der Vergangenheit. Beim landwirtschaftlichen Wegebau hat dies insbesondere Auswirkungen auf die Planung der Kurven. In der Untersuchung wurden die Schleppkurven aktueller Landmaschinen aufgenommen und es wurde geprüft, ob sie mithilfe einer Software simuliert werden können. Dabei zeigt sich, dass die verwendete Simulationssoftware für die Bestimmung von Schleppkurven für Landmaschinen mit komplexen Lenksystemen hinreichend genau ist.

  3. Ethnographische Filme und die Darstellung von Frauen

    Directory of Open Access Journals (Sweden)

    Judith Keilbach

    2002-03-01

    Full Text Available In dieser Filmographie werden ethnographische und koloniale Filme aus dem Bestand des Nederlands Filmmuseum kommentiert, die für die Frage nach der Darstellung von Frauen und Geschlechterverhältnissen von Interesse sind.

  4. Bibliographie der Werke von Herbert Spencer

    OpenAIRE

    Schmid, Michael (Prof.)

    1991-01-01

    Bibliographie der Werke von Herbert Spencer / bearb., hrsg., mit e. Einl. u. e. Kurzbiogr. vers. von Michael Schmid u. Margit Weihrich. - München : Inst. für Soziologie u. Gesellschaftspolitik, Univ. d. Bundeswehr, 1991. - 159 S.

  5. Diskriminierung von Enantiomeren mit chiralen Selektoren

    OpenAIRE

    Würthner, Stefan

    2007-01-01

    Die vorliegende Dissertation befasst sich mit der systematischen Aufklärung von zwischenmolekularen Wirt-Gast-Wechselwirkungen von Arzneistoffen mit Cyclodextrinen. In einem sich trichterförmig verengenden Erkenntnisprozeß wird im ersten Schritt eine breite Datenbasis von Kapillarelektrophorese-Daten von 86 chiralen Arzneistoffen mit 3 nativen CDs (alpha, beta und gamma) sowie 11 CD-Derivaten gewonnen. Sowohl die Trennfaktoren der Enantiomeren (alpha_m) als auch die Retardierungsfaktoren (R_m...

  6. Advanced energy conversion and application - Decentralized energy systems. Papers; Fortschrittliche Energiewandlung und -anwendung - Schwerpunkt: Dezentrale Energiesysteme. Vortraege

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2001-07-01

    Decentralized energy systems is the major topic of this VDI report which contains the proceedings of the VDI conference on advanced energy conversion and application. The decentralized energy systems are in the focus because it is expected that they will gain in significance in the course of restructuring and liberalisation of the energy markets and growing commitment to greenhouse gas mitigation. The subjects of the papers are the cogeneration technology in general, and specific systems for combined generation of heat, power and cold,(CHPC systems), systems for renewable energy generation, industrial energy technology, and analysis and optimization of energy systems. The report is intended to serve as a source of guidance and reference for manufacturers and operators of decentralized energy systems, for decision-making on energy policy, and for the energy industry, counselling firms and regulatory/surveillance bodies, and members of universities involved in relevant research and development work. (orig./CB) [German] Themenschwerpunkt des VDI-Berichts sind die dezentralen Energiesysteme, die im Spannungsfeld von fortschreitender Liberalisierung der Energiemaerkte und der Bemuehungen um die Reduzierung von Emissionen an Bedeutung gewinnen. Dabei widmen sich die Beitraege den Systemen zur Kraft-Waerme-Kaelte-Kopplung und zur Nutzung erneuerbarer Energie sowie der industriellen Energietechnik und der Analyse und Optimierung von Energiesystemen. Der Bericht wendet sich an Hersteller und Betreiber dezentraler Energieanlagen, an Entscheidungstraeger aus Politik und Wirtschaft, an Berater und Ueberwachungsinstitutionen sowie an auf diesem Gebiet taetige Hochschullehrer und -mitarbeiter. (orig.)

  7. Numbered nasal discs for waterfowl

    Science.gov (United States)

    Bartonek, J.C.; Dane, C.W.

    1964-01-01

    Numbered nasal discs were successfully used in studies requiring large numbers of individually marked waterfowl. The procedure for constructing these discs is outlined. Blue-winged teal (Anas discors) with 5/8-inch discs, and canvasback (Aythya valisineria) and redhead (A. americana) with 3/4-inch discs can be individually identified up to 50 and 80 yards, respectively, with a gunstock-mounted, 20-power spotting scope. The particular value of these markers is their durability, the number of combinations possible, and the apparent absence of behavioral or mortality influence among such species as the blue-winged teal.

  8. [Pheochromocytoma and von Recklinghausen's disease].

    Science.gov (United States)

    Rabii, R; Fekak, H; Moufid, K; Joual, A; Bennani, S; el Mrini, M; Benjelloun, S

    2002-07-01

    The association between von Recklinghausen's disease and pheochromocytoma is present about 10% of cases. We report a case of 49 years old women who presented with elevated blood pressure and von Recklinghausen's neurofibromatosis. Laboratory examination showed a marked level in the urinary excretion of cathecholamine. The computed tomography showed a right adrenal tumor suggesting a pheochromocytoma. The adrenalectomy was realised by transabdominal approach and the histological examination confirmed a benign pheochromocytoma. The authors discuss the pathogenetic hypothesis of this rare pathological association, the diagnostic methods and the therapeutic procedure.

  9. An Invitation from Lars von Trier

    DEFF Research Database (Denmark)

    Skadhauge, Troels; Tønder, Lars

    2015-01-01

    Translation of Martin Krasnik interview with Lars von Trier broadcast on DR2, January 12, 2015. The following is an interview of Lars von Trier (LvT) by the Danish journalist Martin Krasnik (MK). The interview took place in Lars von Trier’s home in Brede, a small town just outside Copenhagen...

  10. Transobturatorielle Schlingensysteme (Monarc(R, Serasis TO(R: Ein erster Erfahrungsbericht von 150 Fällen

    Directory of Open Access Journals (Sweden)

    Fischer A

    2005-01-01

    Full Text Available Fragestellung: Überkorrektur mit ihren Begleiterscheinungen Obstruktion und Drangsymptomatik, retropubisches Hämatom und Blasenperforation sind die Hauptkomplikationen der mitturethralen spannungsfreien Bänder und kommen selbst nach fast 2000 Anwendungen immer wieder einmal vor. Zum Teil ist dies abhängig von Voroperationen, der Indikationsstellung, zum Teil auch von der Bandspannung, möglicherweise aber auch vom Weg des Bandes um die Urethra. Die Anwendung eines transobturatoriellen Systems soll nun zeigen, wo die Unterschiede bei dieser unterschiedlichen Technik und Bandverlauf liegen. Methode: 100 transobturatorielle Schlingen vom Typ Monarc(R (AMS, Berlin und 50 transobturatorielle Schlingen Serasis TO(R (Serag-Wiessner, Naila wurden in der Zeit von Anfang Februar bis Mitte Mai 2003 in unserer Klinik eingelegt. Perinealsonographie und Urodynamik inkl. Pad-Test sowie eine körperliche Untersuchung und ein Patientinnenfragebogen zur QoL wurden bei allen Frauen präoperativ und in der Folge nach 6 Wochen, 3 und 6 Monaten postoperativ durchgeführt. Ein Valsalva Leak Point Pressure wurde prä- und postoperativ nach 6 Monaten ermittelt. Der Eingriff erfolgt in Kurznarkose. Ergebnisse: Bei beiden Systemen zeigte sich eine durchschnittliche OP-Zeit von 8–10 Minuten und eine fehlende Hämatombildung sowie eine Blasenläsion bei der Monarc-Anwendung. Sonst trat bei beiden Systemen keine intraoperative Komplikation bei einem durchschnittlichen Blutverlust von ca. 20 ml auf. Perioperativ zeigte sich bei 12 % der mit Monarc behandelten Patienten eine Bakteriurie in den ersten 48 Stunden postoperativ, bei den Serasis-Patientinnen in 4 % der Fälle. Drei Monarc-Bänder und ein Serasis-Band mußten im Zusammenhang mit Drang durchtrennt werden. Fehlende postoperative Wundschmerzen und bis dato praktisch keine Zeichen einer Überkorrektur oder pathologischen Restharnbildung lassen den Unterschied zu den etablierten Inkontinenzoperationen deutlich

  11. Medikamentöse und alternative Konzepte zur Behandlung von Vorhofflimmern: Neuere Klasse-III-Antiarrhythmika, Hybridtherapien (Kardioversion-Defibrillation, Ablation, Pacing

    Directory of Open Access Journals (Sweden)

    Pürerfellner H

    2004-01-01

    Full Text Available Trotz Fortschritten in der nicht-pharmakologischen Therapie spielen antiarrhythmische Medikamente noch immer eine führende Rolle in der Behandlung kardialer Arrhythmien. Große randomisierte kontrollierte klinische Studien haben die Wichtigkeit einer geeigneten Risiko-Nutzen-Evaluierung bei unterschiedlichen Patientengruppen herausgearbeitet. Das hat dazu geführt, daß Natrium-Kanal-Blocker wegen ihrer potentiell proarrhythmischen Wirkung speziell bei Patienten mit eingeschränkter linksventrikulärer Funktion und ischämischer Herzerkrankung immer weniger eingesetzt wurden. Dagegen wurden Betablocker und komplexere Klasse- III-Substanzen wie Sotalol und Amiodaron immer öfter verordnet. Allerdings haben häufig auftretende Nebenwirkungen die Entwicklung von Substanzen mit einer einfachen Ionen-Kanal-Blockade vorangetrieben. In diesem Review werden neuere sogenannte reine Klasse-III-Substanzen diskutiert. Ihr gemeinsamer Wirkmechanismus ist ein antifibrillatorischer Effekt auf Vorhof und Kammer. Klinisch werden sie bei der medikamentösen Kardioversion und zur Prävention von Vorhofflimmern oder Vorhofflattern genauso wie zum Erhalt des Sinusrhythmus nach dessen erfolgreicher Wiederherstellung eingesetzt. Der Bericht enthält eine detaillierte Analyse zur Pharmakokinetik, referiert die Ergebnisse klinischer Studien und erläutert Implikationen in bezug auf die tägliche Anwendung dreier spezieller Substanzen: Ibutilid, Dofetilid und Azimilid. Nachdem ihre Effektivität noch immer begrenzt ist, wird die gegenwärtige und zukünftige Rolle von Hybridtherapien, d. h. eine Kombination von medikamentöser Therapie mit alternativen Behandlungsmethoden (implantierbare Kardioverter-Defibrillatoren, Katheterablation, Schrittmacher diskutiert. Darüber hinaus gibt es einen Ausblick auf ein zukünftiges Medikamentendesign, dessen Ziel das im Sinne eines Remodellings elektrisch veränderte Vorhofgewebe darstellt.

  12. Non-destructive testing of concrete structures with the impact-echo method; Zerstoerungsfreie Pruefung von Betonbauteilen mit dem Impact-Echo-Verfahren

    Energy Technology Data Exchange (ETDEWEB)

    Algernon, Daniel; Feistkorn, Sascha; Scherrer, Michael [SVTI Schweizerischer Verein fuer technische Inspektionen, Wallisellen (Switzerland). Nuklearinspektorat

    2016-05-01

    The impact-echo method is based on the use of elastic waves. It was developed in the 1980 for the testing of concrete structures and is currently widespread. Main application areas are the component and coating thickness measurement and detection of delaminations, voids and other defects. Specifically, the method is also used to check the injection faults of clamping channels. Another application is the determination of mechanical material parameters such as the modulus of elasticity. Since the original development of the method has undergone several enhancements. The conversion of a single-point measurement method towards a area component testing, the use by the optimized measurement data acquisition and evaluation enlarged and delivered an important prerequisite for increasing the efficiency. The use of air-coupled sensors not only increases the measurement speed but also provides advantages in rough component surfaces. The imaging analysis in conjunction with signal processing algorithms simplifies the interpretation and allows statistical evaluation. [German] Das Impact-Echo-Verfahren beruht auf der Nutzung elastischer Wellen. Es wurde in den 1980er Jahren fuer die Pruefung von Stahlbetonbauteilen entwickelt und ist derzeit weit verbreitet. Haupteinsatzgebiete sind die Bauteil- und Schichtdickenmessung sowie die Detektion von Delaminationen, Hohl- und anderen Fehlstellen. Insbesondere wird das Verfahren auch zur Pruefung des Verpresszustandes von Spannkanaelen herangezogen. Eine weitere Anwendung ist die Bestimmung mechanischer Materialparameter wie dem Elastizitaetsmodul. Seit der urspruenglichen Entwicklung hat das Verfahren verschiedene Weiterentwicklungen erfahren. Die Ueberfuehrung von einem Einzelpunktmessverfahren hin zu einer flaechigen Bauteilpruefung hat die Einsatzmoeglichkeiten durch die optimierte Messdatenaufnahme und -auswertung vergroessert und eine wichtige Voraussetzung zur Erhoehung der Leistungsfaehigkeit geliefert. Der Einsatz

  13. Homopteren von Java, gesammelt von Herrn Edw. Jacobson

    NARCIS (Netherlands)

    Melichar, L.

    1914-01-01

    Herr Edw. Jacobson hat auf Java in den Jahren 1908— 1910 Homopteren gesammelt und mir die Bearbeitung des gesammelten Materiales übertragen. Die Jacobson’sche Ausbeute ist insoferne bemerkenswert, als dieselbe viele Mikrohomopteren enthält, welche von nichtfachkundigen Sammlern gewöhnlich nicht

  14. Homopteren von Java, gesammelt von Herrn Edw. Jacobson

    NARCIS (Netherlands)

    Melichar, L.

    1914-01-01

    Herr Edw. Jacobson hat auf Java in den Jahren 1908— 1910 Homopteren gesammelt und mir die Bearbeitung des gesammelten Materiales übertragen. Die Jacobson’sche Ausbeute ist insoferne bemerkenswert, als dieselbe viele Mikrohomopteren enthält, welche von nichtfachkundigen Sammlern gewöhnlich nicht beac

  15. Integration von Erkennung und Interpretation von gesprochener Sprache

    OpenAIRE

    Fink, Gernot A.; Kummert, Franz; Sagerer, Gerhard; Kunze, Jürgen

    1994-01-01

    Die Mehrzahl der heutigen sprachverstehenden Systeme sind aus zwei sehr unterschiedlichen Verarbeitungskomponenten aufgebaut, einer meist statistischen Spracherkennungskomponente und einer in der Regel wissensbasiert arbeitenden Komponente zur Interpretation. Die Kommunikation zwischen diesen Verarbeitungseinheiten ist stark eingeschränkt. In der Regel werden von der Spracherkennung nur Worthypothesenmengen berechnet und an die Interpretationskomponente weitergereicht ohne weitere Interaktion...

  16. Neurofibroma plexiforme de punta nasal

    OpenAIRE

    Pérez B,Sergio; Varela U,Cecilia; Del Villar U,Marcelo

    2009-01-01

    La neurofibromatosis es una enfermedad genética autosómica dominante y de alta penetrancia que pertenece al grupo de los síndromes neurocutáneos. Se sabe de diversas variedades de neurofibromatosis; sin embargo, las más conocidas son la neurofibromatosis tipo 1 (enfermedad de von Recklinghausen) y neurofibromatosis tipo 2 (neurofibromatosis del nervio acústico bilateral). Se presenta el caso clínico de un paciente de 43 años, sexo femenino, sin antecedentes familiares de importancia, quien pr...

  17. NASAL INVERTED PAPILLOMA OF UNUSUAL ORIGIN

    Directory of Open Access Journals (Sweden)

    kasim s. kasim

    2013-12-01

    Full Text Available Two cases of Schneiderian papilloma of the nasal septum are presented. The condition is rare, as indicated by a review of previously published cases. The clinical course of the lesion suggests that it behaves like Schneiderian papillomas elsewhere in the nasal cavity and paranasal sinuses. The need for aggressive surgical management and careful follow-up is emphasized.

  18. ANTHROPOMETRIC STUDY OF NASAL INDEX OF EGYPTIANS

    Directory of Open Access Journals (Sweden)

    Abdelmonem Awad Hegazy

    2014-12-01

    Full Text Available Background: The nasal index determination is one of the most commonly used anthropometric parameters in classifying human races. There are few reports in medical literature concerning nasal index that specifically address particular Egyptian populations. The objective of this study was to determine the normal parameters of external nose (width, height and nasal index in Egyptians. Methods: The study was conducted randomly on healthy Egyptian subjects of both sexes. Nasal height and width were measured using vernier caliper. Then, nasal index was determined for each subject. The obtained data were subjected to statistical analysis. Results: A total of 290 subjects, 144 males and 146 females, aged 1 month– 65 years, were enrolled in the study. The study showed the existence of sexual dimorphism in nasal morphology, appearing after the age 20 years. The mean nasal index in the investigated adults was 68.01; in males and females was 71.46 and 64.56, respectively. Conclusions: The dominant nasal type in Egyptians was in-between mesorrhine "medium" and leptorrhine "narrow" nose. Forensic and anthropological research, as well as cosmetic and reconstructive surgery may benefit from age- and sex- based data of the study.

  19. Rhinoscleroma and nasal non-Hodgkin lymphoma

    Directory of Open Access Journals (Sweden)

    Oliveira, Henrique Fernandes de

    2009-03-01

    Full Text Available Introduction: Rhinoscleroma, a rare nasal granulomatous disease, is caused by Klebsiella rhinoscleromatis. The nose is the primary occurrence region. Nasal non-Hodgkin lymphoma is a rare cancer, and could be of T or B type. The rhinoscleroma and the nasal non-Hodgkin lymphoma present with nasal obstruction as the main symptom, and are part of the nasal granulomatosis differential diagnosis. Objective: To report the association of rhinoscleroma and non-Hodgkin lymphoma in the same patient, by remarking the importance of the nasal granulomatosis' differential diagnosis. Case Report: A forty-nine year old female patient that appeared with a one-month progressive nasal obstruction. Rhinoscopy showed papillomatous feature lesion in left middle meatus. The immunohistochemical analysis confirmed rhinoscleroma. The patient was duly treated with total remission of the lesion. Ten months after, she returned with the same symptoms, but the histologic study confirmed non-Hodgkin lymphoma. Final Comments: Both pathologies may cause more severe nasal symptoms and complications. The early diagnostic enables the choice for the right treatment and contributes for the prognosis. The immunohistochemical study was essential for the diagnostic differentiation.

  20. Nasal Airway Resistance: Its Measurement and Regulation.

    Science.gov (United States)

    Hamilton, Lyle H.

    1979-01-01

    Reviews studies of regulation of nasal airway resistance (Rn). Describes methods of calculating Rn by measuring pressure-flow relationship. Data are presented on improved methods for measuring Rn and effects for expiratory and inspiratory Rn after topical application of phenylephrine nasal decongestant spray. (Author/SA)

  1. Visuelle Analyse von Eye-Tracking-Daten

    OpenAIRE

    2011-01-01

    Eye-Tracking ist eine der am häufigsten eingesetzten Techniken zur Analyse der Mensch-Computer-Interaktion sowie zur Untersuchung der Perzeption. Die erfassten Eye-Tracking-Daten werden meist mit Heat-Maps oder Scan-Paths analysiert, um die Usability der getesteten Anwendung zu ermitteln oder auf höhere kognitive Prozesse zu schließen. Das Ziel dieser Diplomarbeit ist die Entwicklung neuer Visualisierungstechniken für Eye-Tracking-Daten beziehungsweise die Entwicklung eines Studienkonzepts...

  2. Visuelle Analyse von Eye-Tracking-Daten

    OpenAIRE

    Chen, Xuemei

    2011-01-01

    Eye-Tracking ist eine der am häufigsten eingesetzten Techniken zur Analyse der Mensch-Computer-Interaktion sowie zur Untersuchung der Perzeption. Die erfassten Eye-Tracking-Daten werden meist mit Heat-Maps oder Scan-Paths analysiert, um die Usability der getesteten Anwendung zu ermitteln oder auf höhere kognitive Prozesse zu schließen. Das Ziel dieser Diplomarbeit ist die Entwicklung neuer Visualisierungstechniken für Eye-Tracking-Daten beziehungsweise die Entwicklung eines Studienkonzepts...

  3. Assessment of nasalance and nasality in patients with a repaired cleft palate.

    Science.gov (United States)

    Sinko, Klaus; Gruber, Maike; Jagsch, Reinhold; Roesner, Imme; Baumann, Arnulf; Wutzl, Arno; Denk-Linnert, Doris-Maria

    2017-03-15

    In patients with a repaired cleft palate, nasality is typically diagnosed by speech language pathologists. In addition, there are various instruments to objectively diagnose nasalance. To explore the potential of nasalance measurements after cleft palate repair by NasalView(®), we correlated perceptual nasality and instrumentally measured nasalance of eight speech items and determined the relationship between sensitivity and specificity of the nasalance measures by receiver-operating characteristics (ROC) analyses and AUC (area under the curve) computation for each single test item and specific item groups. We recruited patients with a primarily repaired cleft palate receiving speech therapy during follow-up. During a single day visit, perceptive and instrumental assessments were obtained in 36 patients and analyzed. The individual perceptual nasality was assigned to one of four categories; the corresponding instrumental nasalance measures for the eight specific speech items were expressed on a metric scale (1-100). With reference to the perceptual diagnoses, we observed 3 nasal and one oral test item with high sensitivity. However, the specificity of the nasality indicating measures was rather low. The four best speech items with the highest sensitivity provided scores ranging from 96.43 to 100%, while the averaged sensitivity of all eight items was below 90%. We conclude that perceptive evaluation of nasality remains state of the art. For clinical follow-up, instrumental nasalance assessment can objectively document subtle changes by analysis of four speech items only. Further studies are warranted to determine the applicability of instrumental nasalance measures in the clinical routine, using discriminative items only.

  4. Measurement of secretion in nasal lavage

    DEFF Research Database (Denmark)

    Bisgaard, H; Krogsgaard, O W; Mygind, N

    1987-01-01

    secretion to be carried out on the whole sample of lavage fluid, thereby avoiding the necessity of complete admixture between marker and lavage fluid which would be pertinent to marker molecules measured chemically. The radiation from a nasal lavage is minimal and the procedure is fully acceptable...... for repeated use in humans. 4. The nasal lavage technique adopted allowed the return of 99.2% (median value) of the instilled volume. The area irrigated was visualized on a gamma-camera, and was demonstrated to cover an area larger than the area reached by challenge from a pumpspray, i.e. a large part...... of the nose, yet not the oropharynx. 5. A dose related increase in nasal secretion harvested by the nasal lavage in 10 persons challenged with histamine chloride could be demonstrated by this technique. 6. It is concluded that the use of 99mTc-albumin in a nasal washing provides a safe, simple and quick...

  5. [Nasal foreign body in infants].

    Science.gov (United States)

    Claudet, I; Salanne, S; Debuisson, C; Maréchal, C; Rekhroukh, H; Grouteau, E

    2009-09-01

    Provide a descriptive analysis of children admitted to a tertiary care pediatric emergency department (PED) for a nasal foreign body (NFB) and describe the current knowledge and management of such accidents. A retrospective study was conducted from January 2003 to May 2008, including all patients aged less than 15 years admitted for a NFB. The data collected were age, sex, geographic origin, time and day of admission, duration in PED, duration of NFB insertion, nostril location, symptoms and clinical signs, prehospital extraction attempts, facial x-ray, extraction mode, referral to an ENT specialist, progression, and complications. For statistical analysis, the data were entered in Microsoft Excel spreadsheets. The data were analyzed with StatView 5.1 (SAS Institute) and EpiInfo 6.04fr (VF, ENSP Epiconcept). In the descriptive analysis, the data are presented as mean values with standard deviation, median with extreme values or with 95% confidence intervals where appropriate, unless otherwise indicated. To compare qualitative variables, a chi(2) test (Mantel-Haenszel) was used and the two-tailed Fisher exact test if the expected value was 5 or less. Statistical significance was set at pChildren aged less than 4 years accounted for 71% of the studied population. The mean age was 3.5+/-1.6 years (range, 1.4-13 years). The majority of accidents occurred at home (95%). The length of time spent in the PED was 78+/-57 min. The NFB duration of insertion was unknown in one-quarter of cases, present for less than 4 h in 65% of cases. No symptoms were described in most cases (88%). When symptoms were described, bleeding, pain or nasal discomfort, and foul nasal odor were the principal symptoms. The right nostril was the predominant location (60%). This difference tended to disappear in the group of children aged less than 4 years. Five children had bilateral NFB. Nonorganic compounds accounted for 80% of the NFB: plastic beads or balls (39%), plastic or toy parts (20

  6. Functional nasal morphology of chimaerid fishes.

    Science.gov (United States)

    Howard, Lauren E; Holmes, William M; Ferrando, Sara; Maclaine, James S; Kelsh, Robert N; Ramsey, Andrew; Abel, Richard L; Cox, Jonathan P L

    2013-09-01

    Holocephalans (chimaeras) are a group of marine fishes comprising three families: the Callorhinchidae (callorhinchid fishes), the Rhinochimaeridae (rhinochimaerid fishes) and the Chimaeridae (chimaerid fishes). We have used X-ray microcomputed tomography and magnetic resonance imaging to characterise in detail the nasal anatomy of three species of chimaerid fishes: Chimaera monstrosa, C. phantasma and Hydrolagus colliei. We have shown that the nasal chamber of these three species is linked to the external environment by an incurrent channel and to the oral cavity by an excurrent channel via an oral groove. A protrusion of variable morphology is present on the medial wall of the incurrent channel in all three species, but is absent in members of the two other holocephalan families that we inspected. A third nasal channel, the lateral channel, functionally connects the incurrent nostril to the oral cavity, by-passing the nasal chamber. From anatomical reconstructions, we have proposed a model for the circulation of water, and therefore the transport of odorant, in the chimaerid nasal region. In this model, water could flow through the nasal region via the nasal chamber or the lateral channel. In either case, the direction of flow could be reversed. Circulation through the entire nasal region is likely to be driven primarily by the respiratory pump. We have identified several anatomical features that may segregate, distribute, facilitate and regulate flow in the nasal region and have considered the consequences of flow reversal. The non-sensory cilia lining the olfactory sensory channels appear to be mucus-propelling, suggesting that these cilia have a common protective role in cartilaginous fishes (sharks, rays and chimaeras). The nasal region of chimaerid fishes shows at least two adaptations to a benthic lifestyle, and suggests good olfactory sensitivity, with secondary folding enhancing the hypothetical flat sensory surface area by up to 70%.

  7. An assessment of radiological impact of oil-shale flyash in Estonia; Eine Bewertung der radiologischen Wirkung von Oelschieferflugasche in Estland

    Energy Technology Data Exchange (ETDEWEB)

    Realo, K.; Realo, E.; Lust, M. [AN Ehstonskoj SSR, Tartu (USSR). Inst. Fiziki

    1998-07-01

    The concentrations of naturally occurring radionuclides in oil-shale and in different ash fractions were determined by HPGe gamma spectrometry. Volatile fractions of radionuclides discharged via the stacks to the atmosphere (e.g., about 30% of Pb-210) were estimated using the average radionuclide balance. Atmospheric dilution and deposition of flyash radionuclides in the vicinity of the power plants were estimated using a Gauss plume atmospheric dispersion model. The annual and cumulative population doses via inhalation, ingestion and external exposure were calculated. The maximum annual per capita effective dose values of 10.. 20 {mu}Sv x a{sup -1} were obtained. The 30-year cumulative flyash deposition results in the annual doses of the order of 90.. 200 {mu}Sv x a{sup -1}. (orig.) [German] Die Aktivitaetskonzentrationen natuerlicher Radionuklide im Oelschiefer und in verschiedenen Aschefraktionen wurden mittels der HPGe Gammaspektrometrie bestimmt. Die durch Schornsteine in der Atmosphaere freigesetzten fluechtigen Radionuklidfraktionen (z.B. etwa 30% von Pb-210) wurden anhand einer bestimmten durchschnittlichen Radionuklidbilanz geschaetzt. Die atmosphaerische Verduennung und Ablagerung der Flugaschenradionuklide in der Nachbarschaft der Kraftwerke wurden durch Anwendung eines Gauss-Modells fuer atmosphaerische Dispersion geschaetzt. Es wurden die Jahres- und Gesamtbevoelkerungsdosen durch Inhalation, Ingestion und externe Bestrahlung einkalkuliert. Die maximalen Jahreseffektivdosiswerte pro Peron betragen 10... 20 {mu}Sv x a{sup -1}. Durch die 30-jaehrige Gesamtflugaschenablagerung erfolgen die einjaehrigen Dosen in der Groessenordnung von 90... 200 {mu}Sv x a{sup -1}. (orig.)

  8. Technological assessment of demonstration plants for environmentally compatible processing and utilization of liquid manure. Final report; Technologische Bewertung von Demonstrationsanlagen zur umweltvertraeglichen Guelleaufbereitung und -verwertung. Abschlussbericht

    Energy Technology Data Exchange (ETDEWEB)

    Weiland, P.; Huettner, A.

    1997-09-01

    The aim of the BMBF-sponsored research programme ``Environmentally compatible liquid manure processing and utilization`` was to develop and test technical processing methods permitting environmentally friendly storage, application and harnessing of liquid manure. For practical testing and optimization, five demonstration plants were erected, which achieve partial or total cleaning of liquid manure by applying different techniques. All processes had the objective of eliminating from the liquid manure nutrients, organic constituents and odourous components, recovering the nutrients in the form of transportable products, and harnessing the liquid manure for biogas generation. (orig.) [Deutsch] Ziel des BMBF-Foerderschwerpunktes `Umweltvertraegliche Guelleaufbereitung und -verwertung` war es, technische Aufbereitungsverfahren zu entwickeln und zu erproben, die eine umweltvertraegliche Lagerung, Ausbringung und Verwertung der Guelle ermoeglichen. Zur Praxiserprobung und Optimierung wurden fuenf Demonstrationsanlagen errichtet, die durch Anwendung unterschiedlicher Verfahren eine Teil- bzw. Totalreinigung der Guelle bewirken. Aufgabe saemtlicher Verfahren war es, die Guelle von Naehrstoffen, organischen Inhaltsstoffen und Geruchsstoffen zu befreien, die Naehrstoffe in Form transportwuerdiger Produkte zurueckzugewinnen und die Guelle durch Erzeugung von Biogas energetisch zu nutzen. (orig.)

  9. Protecting people and the environment - nuclear applications outside the energy sector; Schutz von Mensch und Umwelt durch nukleare Anwendungen ausserhalb des Energiesektors

    Energy Technology Data Exchange (ETDEWEB)

    Regge, P.P. de [PCI Lab., Internationale Atomenergie Organisation (IAEO), Wien (Austria)

    2002-07-01

    Sicherheitsnormen unterstuetzt. Folgende Schwerpunkte sind aufgrund ihrer besonderen Bedeutung fuer Mensch und Umwelt von besonderem Interesse: - Nuklearmedizin und Gesundheitsvorsorge - Veterinaermedizin und Viehzucht - Bodenkultivierung und Fuengung - Umweltschutz und Wasserversorgung - Pflanzenanbau - Schaedlingsbekaempfung - Landminenraeumung und Schutz von Kulturguetern. Die IAEO kann mit ihren Arbeiten und Erfahrungen von mehreren Jahrzehnten auf umfangreiche Erfolge verweisen. In vielen Laendern konnten durch die Entwicklung und Anwendung nuklearer Technologien z.B. wertvolle Beitraege zur Verbesserung der Ernaehrungssituation, des Gesundheitsschutzes und des Schutzes der Umwelt geleistet werden. Eine Fortfuehrung dieser Aktivitaeten der IAEO liegt im allgemeinen Interesse einer zukunftsweisenden internationalen Entwicklung und Zusammenarbeit. (orig.)

  10. Sindrom Von Hippel–Lindau

    Directory of Open Access Journals (Sweden)

    E V Ershova

    2011-06-01

    Full Text Available Von Hippel-Lindau syndrome - a systemic disease manifesting with multiple tumor growth, inherited by autosomal-dominant type with high penetrance. Understanding the pathogenesis of the disease is important for determining the start time of screening for the presence of the tumors and adequate treatment, including metabolic disorders.

  11. Zur Soziologie von Ctenidium molluscum

    NARCIS (Netherlands)

    Zijlstra, Gea

    1979-01-01

    Bei einer Untersuchung in einer Anzahl von niederländischen „blauwgraslanden“ (d. h. „blaue Wiesen“, Cirsio-Molinietum, Junco-Molinion) wurde Ctenidium molluscum angetroffen, eine Art, welche in den Niederlanden mehr oder weniger zum Mesobromion gerechnet wird. Untersuchungen an altem Herbarmaterial

  12. Continuous and recurrent testing of acoustic emission sensors; Kontinuierliche und wiederkehrende Pruefung von Schallemissionssensoren

    Energy Technology Data Exchange (ETDEWEB)

    Sause, Markus G.R.; Schmitt, Stefan; Potstada, Philipp [Augsburg Univ. (Germany). Inst. fuer Materials Resource Management, Mechanical Engineering

    2017-08-01

    Schallemissionssensoren und ihrer Ankopplung im Labor''. Dieser Beitrag diskutiert Moeglichkeiten zur kontinuierlichen Ueberwachung der Sensoren waehrend der Pruefung und praesentiert ein Anwendungsbeispiel zur teilautomatisierten wiederkehrenden Pruefung von Schallemissionssensoren unter Anwendung der Richtlinie SE 02. Hierzu wurde ein Teststand fuer die Zufuehrung der zu pruefenden Sensoren konstruiert und die Signalaufzeichnung und Datenreduktion in entsprechenden frei verfuegbaren Softwareprogrammen umgesetzt. Anhand ausgewaehlter Fallbeispiele wird die Funktionsweise demonstriert.

  13. Heat piles - a combination of geotechnical and geothermal engineering; Energiepfaehle - Verbindung von Geotechnik und Geothermie

    Energy Technology Data Exchange (ETDEWEB)

    Katzenbach, R.; Rueckert, A. [Technische Univ. Darmstadt (Germany). Inst. fuer Geotechnik; Knoblich, K.; Sanner, B. [Giessen Univ. (Germany). Inst. fuer Angewandte Geowissenschaften; Mands, E. [Prof. Dr. Knoblich und Partner GmbH, Wetzlar (Germany)

    1997-12-01

    , dass aufgrund der vorrangig statischen Bedeutung die Energiepfaehle grundsaetzlich einer geotechnischen Bemessung beduerfen. Bei richtiger Anwendung bietet der Einsatz von Energiepfaehlen ein grosses Potential fuer praktisch alle Gebaeudearten, die an Standorten errichtet werden, an denen eine Tiefgruendung erforderlich ist oder die eine Baugrubenumschliessung benoetigen. Alleine in Deutschland werden pro Jahr rund 5.000 Bauwerke errichtet, fuer die die Nutzung des Bodens und des Grundwassers mittels Energiepfaehlen als Moeglichkeit der ressourcenschonenden Energieversorgung in Frage kommt. (orig.)

  14. Local control and intermediate-term cosmetic outcome following IMRT for nasal tumors. An update

    Energy Technology Data Exchange (ETDEWEB)

    Mukai, Yuki [University Hospital Zurich, Department of Radiation Oncology, Head Neck Cancer Center, Zurich (Switzerland); Yokohama City University Graduate School of Medicine, Department of Radiology, Yokohama (Japan); Janssen, Stefan [University Hospital Zurich, Department of Radiation Oncology, Head Neck Cancer Center, Zurich (Switzerland); Glanzmann, Christoph; Studer, Gabriela [University Hospital Zurich, Department of Radiation Oncology, Head Neck Cancer Center, Zurich (Switzerland); Cantonal Hospital Lucerne, Institute for Radiation Oncology, Lucerne (Switzerland); Holzmann, David [University Hospital Zurich, Department of Otorhinolaryngology, Head and Neck Surgery, Head Neck Cancer Center, Zurich (Switzerland)

    2017-04-15

    This study aims to evaluate local control and intermediate-term cosmetic outcome in patients with cancer of the nose treated with intensity-modulated radiotherapy (IMRT). From June 2008 to September 2015, 36 consecutive patients presenting with nasal cavity, ala of the nose, or nasal vestibule tumors were treated at the Department of Radiation Oncology, University Hospital Zurich either postoperatively (n = 14; 3/14 with nasal ablation) or with definitive IMRT (n = 22). Of these 36 patients, 8 presented with recurrent disease after surgery only and 1/36 with N1 disease. Concurrent systemic therapy was administered in 18/36 patients (50%). Nasal follow-up (FU) imaging documentation of 13 patients with preserved organ and >6 months FU offers a pre/post IMRT FU comparison. In addition, these patients' subjective evaluation of cosmesis was assessed. Mean/median FU was 41/33 months (range 5-92 months). Salvage ablation with curative intent was undergone by 3 patients with local relapse after definitive (n = 2) and postoperative (n = 1) IMRT. The 3-year local control, ultimate local control, and overall survival rates were 90, 97, and 90 %, respectively. Subjective and objective cosmetic outcome after IMRT is very satisfying so far. IMRT for nasal tumors was found to be effective and well tolerated. Intermediate-term cosmetic results are good. Radical surgical procedures may be saved for curative salvage treatment. (orig.) [German] Evaluation der Lokalkontrolle und des mittelfristigen kosmetischen Resultats nach intensitaetsmodulierter Radiotherapie (IMRT) von Patienten mit Nasentumoren. Von Juni 2008 bis September 2015 wurden an der Klinik fuer RadioOnkologie am UniversitaetsSpital Zuerich 36 konsekutive Patienten mit Tumoren der Nasenhoehle, der Nasenfluegel oder des Vestibulum nasi postoperativ (n = 14; 3/14 nach Nasenablation) oder definitiv IMRT-bestrahlt (n = 22). Von diesen 36 Patienten zeigten 8 ein Lokalrezidiv nach alleiniger vorangegangener Chirurgie und

  15. X-ray microtomography, ultrasound and thermography for the characterization of defects in fiberglass and carbon fiber composite materials and elements; Roentgen-Mikrotomografie, Ultraschall und Thermographie fuer die Charakterisierung von Defekten in GFK- und CFK-Verbundwerkstoffen und -Elementen

    Energy Technology Data Exchange (ETDEWEB)

    Brunner, Andreas J.; Jerjen, Iwan; Plamondon, Mathieu; Furrer, Roman; Neuenschwander, Juerg [EMPA Eidgenoessische Materialpruefungs- und Forschungsanstalt, Duebendorf (Switzerland)

    2015-07-01

    Glass and carbon fiber reinforced plastics (GRP or CFRP composites) may have different defects that arise on the one hand in the manufacturing process and on the other hand occur or propagate under quasi-static or oscillating mechanical load. The characterization of the nature, location and size of defects is important among other things for optimization of manufacturing processes, modeling of material or component behavior and for the estimation of the useful life of components or structures from GFK or CFK composites. The contribution shows selected examples of the application of X-ray microtomography, ultrasound and thermography for the characterization of defects in fiberglass or carbon fiber composite components. In ''thick'' laminates and complex shapes the X-ray method is particularly suitable. [German] Glas- und Kohlenstoff-faserverstaerkte Kunststoffe (GFK- bzw. CFK-Verbundwerkstoffe) koennen unterschiedliche Defekte ausweisen, die einerseits im Herstellungsprozess entstehen und sich andererseits bei der Nutzung unter quasistatischer oder schwingender mechanischer Belastung ausbilden oder sich ausbreiten. Die Charakterisierung der Art, der Lage und der Groesse der Defekte ist u.a. fuer Optimierung der Herstellungsprozesse, Modellierung des Werkstoff- oder Bauteilverhaltens sowie der Abschaetzung der Nutzungsdauer von Komponenten oder Strukturen aus GFK- oder CFK-Verbundwerkstoffen wichtig. Der Beitrag zeigt ausgewaehlte Beispiele der Anwendung von Roentgen-Mikrotomografie, Ultraschall und Thermographie zur Charakterisierung von Defekten in GFK- oder CFK-Verbundwerkstoff-Bauteilen. Bei ''dicken'' Laminaten und komplexen Geometrien ist das Roentgenverfahren besonders geeignet.

  16. PET and SPECT investigations in Alzheimer's disease; Nuklearmedizin und Demenz - Anwendung bei Morbus Alzheimer

    Energy Technology Data Exchange (ETDEWEB)

    Asenbaum, S. [Universitaetsklinik fuer Nuklearmedizin, Universitaetsklinik fuer Neurologie, Wien (Austria); Abteilung fuer klinische Neurologie, Universitaetsklinik fuer Neurologie, Waehringer Guertel 18-20, 1090, Wien (Austria)

    2003-07-01

    Nuclear medicine offers a wide range of possibilities to investigate dementia. Various SPECT and PET tracers will be introduced in this article first. Different questions concerning evaluation of dementia are discussed taking Alzheimer's disease (AD) as an example. It is important to perform nuclear medicine investigations on high technical level, using standardized methods as statistical parametric mapping (SPM) for evaluation. If neuroprotective therapies are available, an early diagnosis, the determination of risk factors and longitudinal investigations will be the focus of interest and the main goal of nuclear medicine. Apart from measuring cerebral perfusion and glucose metabolism the development of new ligands, concerning the cholinergic system and the visualization of amyloid plaques, is of great importance. (orig.) [German] Nuklearmedizin bietet bei der Erfassung und Beurteilung eines dementiellen Prozesses eine Vielzahl von Untersuchungsmoeglichkeiten. Anhand des Morbus Alzheimer (DAT) werden in dem vorliegenden Artikel neben einer kurzen Schilderung der zur Verfuegung stehenden Methoden die verschiedenen nuklearmedizinisch relevante Fragestellungen angefuehrt, zu deren Beantwortung die funktionelle Bildgebung Informationen liefern kann. Durch den Einsatz bestimmter, standardisierter Auswerteverfahren wie statistical parametric mapping (SPM) ist es moeglich, entscheidende Hinweise zur Diagnose und Differenzialdiagnose der DAT zu erlangen. In Zukunft werden, insbesondere bei einer Verfuegbarkeit neuroprotektiver Therapien, eine moeglichst fruehe Diagnosestellung und die Erfassung von Risikofaktoren sowie die Moeglichkeit einer Verlaufsbeobachtung in den Mittelpunkt des Interesses und in das Zentrum nuklearmedizinischer Untersuchungen ruecken. Vor allem fuer diese Anforderungen ist neben der qualitaetsvollen Untersuchung von zerebraler Perfusion und Glukosestoffwechsel eine Weiterentwicklung spezieller Liganden v. a. das cholinerge System betreffend und

  17. Involvement of vascular endothelial growth factor in nasal obstruction in patients with nasal allergy

    Directory of Open Access Journals (Sweden)

    Tetsuji Yamashita

    2000-01-01

    Full Text Available It has recently been shown that vascular endothelial growth factor (VEGF enhances vascular permeability and that mast cells produce VEGF, suggesting the involvement of VEGF in allergic diseases. In the present study we quantitatively analyzed VEGF in the nasal lavage fluid of patients with nasal allergy. We performed nasal antigen challenge with Japanese cedar pollen antigen in 10 healthy adult volunteers and in 10 cedar pollen IgE-positive patients with nasal allergy. In all patients with nasal allergy, VEGF and histamine levels in the nasal lavage fluid reached a peak 30 min after antigen challenge, then returned to prechallenge values 2 h after antigen challenge. In these patients, the histamine level increased three-fold, while the VEGF level increased 10-fold. However, in all healthy adult volunteers, VEGF and histamine levels did not increase. A stronger correlation was noted between the ratio of decreased nasal cavity volume and the ratio of increased VEGF levels (R = 0.823; P < 0.001 than between the ratio of nasal cavity volume and the ratio of increased histamine levels (R = 0.660; P < 0.01. These results suggest that VEGF may contribute to the pathogenesis of nasal obstruction in the early phase of nasal allergy as a new factor involved in increasing vascular permeability.

  18. [Friedrich Ludwig von Maydelli pildid Baltimaade ajaloost = Friedrich Ludwig von Maydells Baltische Geschichte in Bildern = Friedrich Ludwig von Maydell ́s Baltic history in images] / Ulrike Plath

    Index Scriptorium Estoniae

    Plath, Ulrike, 1972-

    2014-01-01

    Arvustus: Friedrich Ludwig von Maydelli pildid Baltimaade ajaloost = Friedrich Ludwig von Maydells Baltische Geschichte in Bildern = Friedrich Ludwig von Maydell ́s Baltic history in images. Eesti kunstimuuseum, Kadrioru kunstimuuseum. Tallinn 2013

  19. [Friedrich Ludwig von Maydelli pildid Baltimaade ajaloost = Friedrich Ludwig von Maydells Baltische Geschichte in Bildern = Friedrich Ludwig von Maydell ́s Baltic history in images] / Ulrike Plath

    Index Scriptorium Estoniae

    Plath, Ulrike, 1972-

    2014-01-01

    Arvustus: Friedrich Ludwig von Maydelli pildid Baltimaade ajaloost = Friedrich Ludwig von Maydells Baltische Geschichte in Bildern = Friedrich Ludwig von Maydell ́s Baltic history in images. Eesti kunstimuuseum, Kadrioru kunstimuuseum. Tallinn 2013

  20. Endoscopic removal of nasal septum chondrosarcoma in paediatric patient

    Directory of Open Access Journals (Sweden)

    Muhammad Nasri Abu Bakar

    2014-07-01

    We report a boy with progressive history of nasal obstruction and epistaxis. Nasal endoscopy revealed a mass arising from nasal septum. Endoscopic excision of the tumour was successfully done followed by radiotherapy. Endoscopic excision of chondrosarcoma of the nasal septum in its early stage should be considered for better outcome.

  1. Einfluss von hormonellen Kontrazeptiva auf das Größenwachstum und den Knochenbau von 12-14-jährigen Mädchen: Stellungnahme der DGGEF

    Directory of Open Access Journals (Sweden)

    Rabe T

    2009-01-01

    Full Text Available Für die normale Funktion und Stabilität des Knochens ist der regelrechte Aufbau der Knochenmasse und -struktur während der Wachstumsphase in der Jugend bis zum 25. Lebensjahr erforderlich. Orale hormonale Kontrazeptiva, die aus therapeutischen Gründen bzw. zur Kontrazeption von 12–14-jährigen Mädchen (insbesondere auch Sportlerinnen eingenommen werden, sollen weder den Knochenaufbau noch das Größenwachstum beeinflussen. Im Rahmen dieser Arbeit werden die Steuerung des Größenwachstums, die Bedeutung der Körpergröße für das einzelne Mädchen, Parameter zur Beurteilung der Körpergröße in einer Wachstumsprognose, die Hormonbehandlung bei Großwuchs, der Einsatz hormonaler Kontrazeptiva bei den 12–14- jährigen Mädchen sowie der Einfluss der Steroidhormone auf den Knochen zusammengefasst. Bei Jugendlichen ist nach der Etablierung des menstruellen Zyklus durch die Einnahme einer Pille nicht mit einer nachteiligen Wirkung auf das Größenwachstum zu rechnen. Ob durch die Einnahme der Pille bei Jugendlichen die maximale Peak-Bone-Mass eines Kontrollkollektivs ohne Pille erreicht wird, muss weiter untersucht werden. Hierbei sind insbesondere die Lebensumstände (z. B. bekannte genetische Disposition, Ernährungszustände zu berücksichtigen. Der möglicherweise geringe negative Effekt der Pille bei Jugendlichen auf die Peak-Bone-Mass muss im Rahmen der üblichen Risiko-Nutzen- Analyse bewertet werden. Hierbei überwiegt eindeutig der Nutzen der Pille, zumal nicht bewiesen ist, wie die Peak-Bone-Mass durch die unterschiedlichen Kontrazeptiva beeinflusst wird und wenn dies der Fall sein sollte, ob diese geringere Peak-Bone-Mass mit einem erhöhten Frakturrisiko in Zusammenhang steht. Die Anwendung von Depotgestagenen (z. B. Dreimonatsspritze bei Jugendlichen wird nicht empfohlen, da möglicherweise die Knochendichte und das Frakturrisiko beeinflusst werden könnten. Weiterhin ist bei jungen Sportlerinnen eine gesunde Ernährung für den

  2. Nasal obstruction and smell impairment in nasal polyp disease: correlation between objective and subjective parameters.

    Science.gov (United States)

    Hox, V; Bobic, S; Callebaux, I; Jorissen, M; Hellings, P W

    2010-12-01

    Chronic rhinosinusitis with nasal polyposis (NP) represents an invalidating disorder that causes mainly nasal blockage and loss of smell. The aim of this study is to investigate correlations between individual subjective and objective parameters of stable NP disease. 65 NP patients scored their sinonasal symptoms on a visual analogue scale (VAS) and questionnaires (SNOT-22 and SF-36). Peak nasal inspiratory flow (PNIF) measurement, Sniffinatm Sticks (SS) smell test, blood analysis for eosinophilia, total IgE and culture for Staphylococcus aureus (SA) were performed. VAS scores for nasal blockage correlated with the SNOT-22 and SF-36 scores, which was not observed for VAS of other symptoms. VAS scores for nasal blockage correlated well with PNIF values as well as VAS scores for smell dysfunction and SS results (both psmell reduction (psmell reduction in NP disease. Nasal blockage is the only symptom that correlates well with NP size and SNOT-22 scores, whereas smell reduction correlates with blood eosinophilia.

  3. Ingenieurgeologie: Grundlagen und Anwendung

    Science.gov (United States)

    Genske, Dieter D.

    Geplünderter Planet? Die Ingenieurgeologie ist ein junges, interdisziplinäres Fachgebiet. Es befasst sich mit der Wechselwirkung zwischen Geosphäre und Mensch. Der Autor stellt Georisiken vor und diskutiert die Folgen menschlicher Eingriffe in die Natur. Er thematisiert aktuelle Herausforderungen und entwirft nachhaltige Lösungskonzepte für verschiedene Problembereiche: z.B. Naturgefahren wie Hangrutschungen und Bergfälle, die Ausbeute natürlicher Ressourcen, Bau- und Sanierungsvorhaben. Fallbeschreibungen und ausgearbeitete Beispiele vertiefen das Verständnis für diesen neuen, zukunftsweisenden Zweig der Wissenschaft.

  4. Linear open-loop and closed-loop control theory. Modelling of control paths, robust stability, design of robust controllers, trajectory control with follow-up contorl, polynomial description of MIMO systems, time discrete control loops and scanning control loops; Lineare Regelungs- und Steuerungstheorie. Modellierung von Regelstrecken, Robuste Stabilitaet und Entwurf robuster Regler, Trajektoriensteuerung mit Folgeregelung, Polynomiale Beschreibung von MIMO-Systemen, Zeitdiskrete und Abtastregelkreise

    Energy Technology Data Exchange (ETDEWEB)

    Reinschke, K. [Technische Univ. Dresden (Germany). Inst. fuer Regelungs- und Streuerungstheorie

    2006-07-01

    Zusammenhaenge, die sowohl den Entwurf robuster stabilisierender Regler als auch die Trajektoriensteuerung mit Folgeregelung sowie die zeitkontinuierliche Behandlung von Abtastregelkreisen ermoeglichen. Zahlreiche Beispiele illustrieren die Anwendung der allgemeinen Gesetzmaessigkeiten. (orig.)

  5. Micro- and macromechanical simulation of the deformation of steels under consideration of transformation and diffusion processes; Mikro- und makromechanische Simulation des Deformationsverhaltens von Staehlen unter Beruecksichtigung von Umwandlungs- und Diffusionsvorgaengen

    Energy Technology Data Exchange (ETDEWEB)

    Daves, W.

    1994-12-31

    The goal of the present work was to develop a continuum mechanical description of the deformation behaviour of steels and cast iron, which makes it possible to calculate the residual stresses during and after heat treatment. The formation of microresidual stresses at transformation processes is discussed. In a survey, analytical and numerical models existing and developed by the author are presented for the transformation and the dispersion plasticity. The further calculation of the residual stresses in composite rollers is done using the preset transformation plasticity models. For the simulation of nitriding, a continuum mechanical concept is developed, which considers the diffusion of nitrogen into the material, the kinetics of nitride formation, the volume change in the nitride layer in consequence of the interstitial nitrogen and of the nitrides, the plastifying, the creep and a hardness increase of the material during nitriding. The results agree very well in their quality with the measurements. The material model used for the calculations is described in detail. (orig.) [Deutsch] Das Ziel der vorliegenden Arbeit ist es, eine kontinuumsmechanische Beschreibung des Deformationsverhaltens von Staehlen und Gusseisen zu entwickeln, welche es ermoeglicht, die Eigenspannungen waehrend und nach einer Waermebehandlung zu berechnen. Zu Beginn wird die Entstehung von Mikroeigenspannungen bei Umwandlungsvorgaengen behandelt. In einer Uebersicht werden bestehende und vom Verfasser entwickelte analytische und numerische und numerische Modelle fuer die Umwandlungs- und Ausscheidungsplastizitaet vorgestellt. Weiteres erfolgt die Berechnung der Eigenspannungen in Verbundwalzen unter Anwendung der vorgestellten Umwandlungsplastizitaetsmodelle. Fuer die Simulation des Nitrierens wird ein kontinuumsmechanisches Konzept entwickelt, welches die Diffuson des Stickstoffes in das Material, die Kinetik der Nitridbildung, die Volumsaenderung in der Nitridschicht zufolge des

  6. Effect of Local Nasal Immunotherapy on Nasal Blockage in Pollen-Induced Allergic Rhinitis of Guinea Pigs

    Directory of Open Access Journals (Sweden)

    Takeshi Nabe

    2008-01-01

    Conclusions: Local nasal immunotherapy may be clinically useful for allergic nasal blockage associated with nasal hyperresponsiveness. The mechanisms responsible for this effectiveness might not be related to IgE production. Additionally, the effectiveness for nasal tissue was dissociated from that seen for the ocular tissue.

  7. Schätzung von Vegetationsparametern aus multispektralen Fernerkundungsdaten

    OpenAIRE

    2007-01-01

    In der vorliegenden Arbeit wird ein Verfahren zur Schätzung von Vegetationsparametern aus multispektralen Fernerkundungsdaten unter Verwendung von physikalischen Strahlungstransfer-Modellen und einer geringen Anzahl von Bodenmessungen vorgestellt. Dieses Verfahren wurde über einen Zeitraum von zwei Jahren exemplarisch an verschiedenen Winterweizenfeldern getestet, die mit einem Daedalus ATM Multispektralscanner aufgenommen wurden. Von besonderem Interesse sind hierbei die Schwankungen der Veg...

  8. Enhancing the safety and efficiency of the driving gear of coal mining machinery by using water as a hydraulic fluid and enhancing the reliability of scraper-chain conveyors; Erhoehung der Sicherheit und Leistungsfaehigkeit der Antriebstechnik von Arbeitsmaschinen durch Verwendung von Wasserhydraulik sowie Erhoehung der Zuverlaessigkeit der Kettenkratzerfoerderer

    Energy Technology Data Exchange (ETDEWEB)

    Reichel, J.; Boeing, R.; Graetz, A.; Loehning, H.D.; Plum, D.

    1997-12-31

    The objective pursued is to increasingly use water or high water-content fluids as a substitute for other hydraulic fluids in driving gear of mining machinery. The state of the art of the technology is represented only by individual solutions achieved for given purposes which are not suitable for other applications, let alone for coal mining machinery. The research project was to identify hydraulic components that will permit the use of water or watery substances as a hydraulic fluid in mining applications. The components have been found and further developed, and finally systems with linear and rotatory drives have been tested at various test facilities in order to derive information on the system behaviour of pressurized fluids and machinery components and their suitability for coal mining applications. (orig./CB) [Deutsch] In der untertaegigen Antriebstechnik sollen vermehrt Wasser und wasserhaltige Fluessigkeiten eingesetzt werden. Der Stand der Technik fuehrt bei der Anwendung von Wasserhydraulik immer wieder nur Einzelloesungen auf, die nicht allgemein und insbesondere im Steinkohlenbergbau angewendet werden koennen. Im Rahmen dieses Forschungsvorhabens wurden fuer die Wasserhydraulik geeignete Komponenten untersucht, weiterentwickelt und schliesslich Systeme mit linearen und rotatorischen Antrieben auf verschiedenen Pruefstaenden erprobt, um Aussagen ueber das Systemverhalten von Druckfluessigkeit und Bauelementen fuer Bergbauanwendungen zu bekommen. (orig./MSK)

  9. Shock, diaschisis and von Monakow

    Directory of Open Access Journals (Sweden)

    Eliasz Engelhardt

    2013-07-01

    Full Text Available The concept of shock apparently emerged in the middle of the 18th century (Whyett as an occurrence observed experimentally after spinal cord transection, and identified as "shock" phenomenon one century later (Hall. The concept was extended (Brown-Séquard and it was suggested that brain lesions caused functional rupture in regions distant from the injured one ("action à distance". The term "diaschisis" (von Monakow, proposed as a new modality of shock, had its concept broadened, underpinned by observations of patients, aiming at distinguishing between symptoms of focal brain lesions and transitory effects they produced, attributable to depression of distant parts of the brain connected to the injured area. Presently, diaschisis is related mainly to cerebrovascular lesions and classified according to the connection fibers involved, as proposed by von Monakow. Depression of metabolism and blood flow in regions anatomically separated, but related by connections with the lesion, allows observing diaschisis with neuroimaging.

  10. A model of airflow in the nasal cavities: Implications for nasal air conditioning and epistaxis.

    Science.gov (United States)

    Bailie, Neil; Hanna, Brendan; Watterson, John; Gallagher, Geraldine

    2009-01-01

    A friction force is generated when moving air contacts the nasal walls, referred to as wall shear stress. This interaction facilitates heat and mass transfer between the mucosa and air, i.e., air-conditioning. The objective of this research was to study the distribution of wall shear stress within the nasal cavity to identify areas that contribute significantly to air-conditioning within the nasal cavity. Three-dimensional computational models of the nasal airways of five healthy subjects (three male and two female subjects) were constructed from nasal CT scans. Numerical simulations of nasal airflow were conducted using the commercial computational fluid dynamics code Fluent 6 (Ansys, Inc., Canonsburg, PA). Wall shear stress was derived from the numerical simulation. Air-conditioning was simulated to confirm the relationship with wall shear stress. Nasal airflow simulations predicted high wall shear stress along the anterior aspect of the inferior turbinate, the anteroinferior aspect of the middle turbinate, and within Little's area. The airflow simulations indicate that the inferior and middle turbinates and Little's area on the anterior nasal septum contribute significantly to nasal air-conditioning. The concentration of wall shear stress within Little's area indicates a desiccating and potentially traumatic effect of inhaled air that may explain the predilection for spontaneous epistaxis at this site.

  11. Influence of cooling face masks on nasal air conditioning and nasal geometry.

    Science.gov (United States)

    Lindemann, J; Hoffmann, T; Koehl, A; Walz, E M; Sommer, F

    2017-06-01

    Nasal geometries and temperature of the nasal mucosa are the primary factors affecting nasal air conditioning. Data on intranasal air conditioning after provoking the trigeminal nerve with a cold stimulus simulating the effects of an arctic condition is still missing. The objective was to investigate the influence of skin cooling face masks on nasal air conditioning, mucosal temperature and nasal geometry. Standardized in vivo measurements of intranasal air temperature, humidity and mucosal temperature were performed in 55 healthy subjects at defined detection sites before and after wearing a cooling face mask. Measurements of skin temperature, rhinomanometry and acoustic rhinometry were accomplished. After wearing the face mask the facial skin temperature was significantly reduced. Intranasal air temperature did not change. Absolute humidity and mucosal temperature increased significantly. The acoustic rhinometric results showed a significant increase of the volumes and the cross-sectional areas. There was no change in nasal airflow. Nasal mucosal temperature, humidity of inhaled air, and volume of the anterior nose increased after application of a cold face mask. The response is mediated by the trigeminal nerve. Increased mucosal temperatures as well as changes in nasal geometries seem to guarantee sufficient steady intranasal nasal air conditioning.

  12. Perceiving nasal patency through mucosal cooling rather than air temperature or nasal resistance.

    Directory of Open Access Journals (Sweden)

    Kai Zhao

    Full Text Available Adequate perception of nasal airflow (i.e., nasal patency is an important consideration for patients with nasal sinus diseases. The perception of a lack of nasal patency becomes the primary symptom that drives these patients to seek medical treatment. However, clinical assessment of nasal patency remains a challenge because we lack objective measurements that correlate well with what patients perceive. The current study examined factors that may influence perceived patency, including air temperature, humidity, mucosal cooling, nasal resistance, and trigeminal sensitivity. Forty-four healthy subjects rated nasal patency while sampling air from three facial exposure boxes that were ventilated with untreated room air, cold air, and dry air, respectively. In all conditions, air temperature and relative humidity inside each box were recorded with sensors connected to a computer. Nasal resistance and minimum airway cross-sectional area (MCA were measured using rhinomanometry and acoustic rhinometry, respectively. General trigeminal sensitivity was assessed through lateralization thresholds to butanol. No significant correlation was found between perceived patency and nasal resistance or MCA. In contrast, air temperature, humidity, and butanol threshold combined significantly contributed to the ratings of patency, with mucosal cooling (heat loss being the most heavily weighted predictor. Air humidity significantly influences perceived patency, suggesting that mucosal cooling rather than air temperature alone provides the trigeminal sensation that results in perception of patency. The dynamic cooling between the airstream and the mucosal wall may be quantified experimentally or computationally and could potentially lead to a new clinical evaluation tool.

  13. Moose von Inselbergen in Benin

    OpenAIRE

    Frahm, Jan-Peter; Porembski, Stefan

    1998-01-01

    Acht Leber- und zehn Laubmoosarten werden von Inselbergen aus Benin angegeben. Fünf der Lebermoose (Acrolejeunea emergens, Riccia atropurpurea, R. congoana, R. discolor, R. moenkemeyeri) und alle Laubmoose (Archidium ohioense, Brachymenium acuminatum, B. exile, Bryum arachnoideum, B. argenteum, Bryum deperssum, Garckea moenkemeyeri, Hyophila involuta, Philonotis mniobryoides und Weissia cf. edentula) werden neu für Benin angegeben. Eight liverworts and ten mosses are reported from inselber...

  14. Nasal Mucociliary Transport Before and After Jogging.

    Science.gov (United States)

    Cederlund, Anna; And Others

    1987-01-01

    A study of nasal mucociliary transport in 11 healthy subjects before and after they jogged 8-10 kilometers indicated that the transport time was significantly longer after jogging than before jogging. (Author/CB)

  15. Radiological changes and complications associated with nasal ...

    African Journals Online (AJOL)

    Radiological changes and complications associated with nasal polyposis. *A.().A. Ogunleye and ... polyposis patients seen at the department of Otorhin0- llaryngology of .... Long-standing nasasl polyps can enlarge to such a degree that they ...

  16. Nasal septal teratoma in a child

    Directory of Open Access Journals (Sweden)

    Akinyemi Oluwole A

    2007-05-01

    Full Text Available Abstract Background Teratoma is a rare developmental neoplasm that arises from totipotential tumor stem cells. Head and neck teratomas constitute about 10% of all cases. Only two cases of mature teratoma of the nasal septum have previously been documented in the world literature. Case presentation We present a case of histologically confirmed mature teratoma arising from the nasal septum in an eighteen month old Nigerian female who presented with a history of noisy breathing associated with recurrent rhinorrhea since birth. Physical examination revealed obstruction of the right nasal cavity by a pale fleshy mass. She underwent a total surgical excision and to date, after thirty one months follow-up, she is free from recurrence. Conclusion The prognosis for benign teratoma of the nasal septum is good following total surgical excision.

  17. Effect of bilastine upon nasal obstruction.

    Science.gov (United States)

    Dávila, I; Sastre, J; Mullol, J; Montoro, J; Jáuregui, I; Ferrer, M; del Cuvillo, A; Bartra, J; Valero, A

    2011-01-01

    H1 antihistamines constitute one of the main references for the treatment of allergic rhinitis. Classically, these drugs have been considered effective in controlling sneezing, rhinorrhea and itching, though they have not been regarded as particularly effective in application to nasal obstruction. The most recent studies, involving second-generation H1 antihistamines (desloratadine, fexofenadine, levocetirizine, rupatadine), have shown these drugs to offer effects upon nasal obstruction significantly superior to those of placebo. The present review examines the effect of bilastine, a new, potent and highly specific H1 antihistamine without sedative effects or cardiac toxicity, upon nasal obstruction. The analysis of the data from the different clinical trials indicates that in patients with allergic rhinitis, the effect of bilastine upon nasal obstruction is superior to that of placebo and similar to that of other second-generation H1 antihistamines, manifesting within 24 hours after the start of treatment.

  18. Unilateral nasal pain with migraine features.

    Science.gov (United States)

    Alvarez, Mónica; Montojo, Teresa; de la Casa, Beatriz; Vela, Lydia; Pareja, Juan A

    2013-09-01

    Migraine attacks exclusively felt in the face are very rare, the pain involving the territories supplied by the second and third branches of the trigeminal nerve. Two patients suffering from heminasal pain attacks accompanied with typical migrainous features and responsive to oral or intranasal triptans - but not to intranasal lidocaine or oxymetazoline. In one patient, the attacks could be precipitated upon slight touching on the tip of the nose, in the other attacks were preceded by the nasal sensation typically heralding sneezing. Migraine pain mostly develops within the innervation territory of the first branch of the trigeminal nerve, which includes the nose. Therefore, episodes of unilateral nasal pain with migrainous features could be considered a migraine with unusual topography (nasal migraine). Painful nasal attacks occasionally preceded by stimulation of trigeminal afferents in the nose, could be conceived of as migraine-tic syndrome.

  19. Development of the cetacean nasal skull.

    Science.gov (United States)

    Klima, M

    1999-01-01

    The adaptation of cetaceans to aquatic life habits is reflected, in their nasal region, in three marked changes from the original relations found in land mammals. These changes include (1) the loss of the sense of smell, (2) translocation of the nostrils from the tip of the rostrum to the vertex of the head, and (3) elongation of the anterior head to form a rostrum protruding far towards anterior. The morphogenetic processes taking place during embryogenesis of the nasal skull play a decisive part in the development of all these changes. The lateral parts of the embryonic nasal capsule, encompassing the nasal passages, change their position from horizontal to vertical. At the same time, the structures of the original nasal floor (the solum nasi) are shifted in front of the nasal passages towards the rostrum. The structures of the original nasal roof (the tectum nasi) and of the nasal side wall (the paries nasi) are translocated behind the nasal passages towards the neurocranium. The medial nasal septum (the septum nasi) mostly loses its connection to the nasal passages and is produced into a point protruding far towards anterior. The transformed embryonic nasal skull of the Cetacea can be divided into three sections: 1. The median structures. These include the cartilaginous structures, viz., the rostrum nasi, the septum interorbitale and the spina mesethmoidalis, which are accompanied by the dermal bones, the vomer and the praemaxillare. In adult cetaceans the rostrum nasi is mostly preserved as a robust cartilage of the skull, which may possibly serve as a sound transmitting structure of the sonar system, or it may be responsible for the sensing of water streams and vibrations. 2. The posterior side wall structures. These include the following cartilaginous structures that are mostly heavily reduced or mutually fused: the cupula nasi anterior, the tectum nasi, the lamina cribrosa, the paries nasi, the commissura orbitonasalis, the cupula nasi posterior, the

  20. Local Nasal Specific Immunotherapy for Allergic Rhinitis

    Directory of Open Access Journals (Sweden)

    Passalacqua Giovanni

    2006-09-01

    Full Text Available Abstract The possibility of producing local hyposensitization by administering allergens via mucosal routes was envisaged at the beginning of 1900, and local nasal immunotherapy has been extensively studied since the 1970s. Presently, there are 21 randomized controlled trials being conducted with the most common allergens, consistently showing the clinical efficacy of local nasal immunotherapy for rhinitis. Other advantages are that it has an optimal safety profile and can be self-administered at home by the patient. Moreover, there are several data from animal models and from humans that confirm the immunomodulatory effect of intranasally administered antigens. On the other hand, local nasal immunotherapy seems to be effective only on rhinitis symptoms and requires a particular technique of administration. For these reasons, its clinical use is progressively declining in favour of the sublingual route although nasal immunotherapy is validated in official documents and remains a viable alternative to injection.

  1. Primary nasal tuberculosis: a case report.

    Science.gov (United States)

    Nayar, Ravi C; Al Kaabi, Juma; Ghorpade, Kanchanmala

    2004-03-01

    During the past 2 decades, tuberculosis--both pulmonary and extrapulmonary--has re-emerged as a major health problem worldwide. Nasal tuberculosis--either primary or secondary to pulmonary tuberculosis or facial lupus--is rare, but it should be considered in the differential diagnosis of nasal granulomas. We describe a case of primary nasal tuberculosis in an adult male who presented with a polypoid lesion in one nasal cavity. The diagnosis was based on histopathology and the patient's successful response to antituberculous drug treatment. Given the rising incidence of tuberculosis, it is prudent that otolaryngologists remain cognizant of this infection as a potential cause of unusual lesions in the head and neck.

  2. Didaktische Konzeption von Serious Games: Zur Verknüpfung von Spiel- und Lernangeboten

    Directory of Open Access Journals (Sweden)

    Michael Kerres

    2009-08-01

    Full Text Available Serious Games versuchen Spielen mit Lernen zu verbinden. Der Beitrag problematisiert die Machbarkeit einer solchen Verknüpfung in digitalen Welten und diskutiert verschiedene didaktische Konzepte einer Nutzbarmachung digitaler Spiele für das Lernen und Lehren. Ausgehend von einer Analyse des Erlernens von Spielen werden drei didaktische Konzepte von Serious Games im Hinblick auf ihre didaktischen Potenziale untersucht: (1 der unmittelbare Transfer von Wissen, das im Spiel erworben wird (keine zusätzliche Didaktisierung, (2 Didaktisierung durch Einbettung des Spiels in einer Lernsituation oder (3 Didaktisierung durch Einbettung von Lernaufgaben in ein Spiel. Ergebnisse zur Nutzung von Spielen, bei denen Lernaufgaben in eine Spielwelt eingebettet sind, zeigen, dass Personen die Aufnahme von Wissen in einem expliziten Lernmodus eher zu reduzieren versuchen, um möglichst zügig wieder in den Spielmodus zu wechseln. Diskutiert werden die Konsequenzen dieser Problematik für die didaktische Konzeption von Serious Games.

  3. Numerical simulation and nasal air-conditioning

    Directory of Open Access Journals (Sweden)

    Keck, Tilman

    2010-01-01

    Full Text Available Heating and humidification of the respiratory air are the main functions of the nasal airways in addition to cleansing and olfaction. Optimal nasal air conditioning is mandatory for an ideal pulmonary gas exchange in order to avoid desiccation and adhesion of the alveolar capillary bed. The complex three-dimensional anatomical structure of the nose makes it impossible to perform detailed in vivo studies on intranasal heating and humidification within the entire nasal airways applying various technical set-ups. The main problem of in vivo temperature and humidity measurements is a poor spatial and time resolution. Therefore, in vivo measurements are feasible only to a restricted extent, solely providing single temperature values as the complete nose is not entirely accessible. Therefore, data on the overall performance of the nose are only based on one single measurement within each nasal segment. In vivo measurements within the entire nose are not feasible. These serious technical issues concerning in vivo measurements led to a large number of numerical simulation projects in the last few years providing novel information about the complex functions of the nasal airways. In general, numerical simulations merely calculate predictions in a computational model, e.g. a realistic nose model, depending on the setting of the boundary conditions. Therefore, numerical simulations achieve only approximations of a possible real situation. The aim of this review is the synopsis of the technical expertise on the field of in vivo nasal air conditioning, the novel information of numerical simulations and the current state of knowledge on the influence of nasal and sinus surgery on nasal air conditioning.

  4. Open safety pin in the nasal cavity.

    Science.gov (United States)

    Sen, I; Sikder, B; Sinha, R; Paul, R

    2004-04-01

    Foreign bodies in the nasal cavity are common-day occurrences in Otolaryngologic practice. But an open safety pin in nose with it' s sharp end directed towards roof is a rare incidence, and available literature is silent about this presentation; it is probably, the first of it' s kind being reported. Two cases of safety pins inside the nasal cavity, one open and the other closed, have been presented here with a brief review of literature.

  5. Open safety pin in the nasal cavity

    OpenAIRE

    Sen, I; Sikder, B.; R. Sinha; Paul, R

    2004-01-01

    Foreign bodies in the nasal cavity are common-day occurrences in Otolaryngologic practice. But an open safety pin in nose with it’ s sharp end directed towards roof is a rare incidence, and available literature is silent about this presentation; it is probably, the first of it’ s kind being reported. Two cases of safety pins inside the nasal cavity, one open and the other closed, have been presented here with a brief review of literature.

  6. [Nasal and pulmonary flora in the goat].

    Science.gov (United States)

    Richard, Y; Borges, E; Favier, C; Oudar, J

    1989-01-01

    On the basis of bacteriological examinations carried out on 75 intranasal swabs and 80 goat lung punctures, aerobic, aero-anaerobic respiratory microbes and mycoplasma were studied. Mycoplasma ovipneumoniae was isolated both from nasal flora (37%) and from the lungs (27.5%) as well as Pasteurella spp which accounted respectively for 24% and 12.5%. The nasal flora are characterised by the presence of a Gram-negative strain included in the genus Moraxella and connected with Moraxella bovis species.

  7. Pharmacology of Nasal Medications: An Update

    OpenAIRE

    Martin, G. F.

    1988-01-01

    The author of this article reviews the pharmacology of nasal medication, focusing on the indications and side-effects. The newer group of non-sedating antihistamines proves to be a useful supplement to disodium cromoglycate and the traditional antihistamines in the treatment of allergic rhinitis. The topical steroids (flunisolide and beclomethasone dipropionate) did not produce a significant incidence of adrenal suppression, mucosal atrophy, or nasal candidiasis. The anticholinergic ipatropiu...

  8. Oral and nasal microbiota in Parkinson's disease.

    Science.gov (United States)

    Pereira, Pedro A B; Aho, Velma T E; Paulin, Lars; Pekkonen, Eero; Auvinen, Petri; Scheperjans, Filip

    2017-05-01

    Parkinson's disease (PD) is associated with neuropathological changes in olfactory and gastrointestinal tissues, and PD patients frequently suffer from hyposmia, hyposalivation, and dysphagia. Since hyposmia and gastrointestinal dysfunction are frequently premotor symptoms, it has been speculated that an external, for example microbial, agent could trigger the pathologic process in the corresponding organs, subsequently spreading to the central nervous system. We recently showed evidence for compositional differences between the fecal microbiota of PD patients and control subjects. In this study, our objective was to explore a possible connection between nasal and oral microbiota and PD. We compared the oral and nasal bacterial communities of PD patients (oral: n = 72, nasal: n = 69) and control subjects (oral: n = 76, nasal: n = 67) using a 16S rRNA gene amplicon sequencing approach. Oral and nasal microbiota differed markedly from each other, with no notable similarity within subjects. Oral microbiota of PD patients and control subjects had differences in beta diversity and abundances of individual bacterial taxa. An increase in the abundance of opportunistic oral pathogens was detected in males, both with and without PD. Our data did not reveal convincing differences between the nasal microbiota of control subjects and PD patients. The oral microbiome deserves additional research regarding its connection to PD and its biomarker potential. The higher abundance of oral pathogens in men underlines the importance of monitoring and promoting male dental health. Copyright © 2017 Elsevier Ltd. All rights reserved.

  9. NASALIZATION IN BRAZILIAN PORTUGUESE: AN AUTOSEGMENTAL (REVIEW

    Directory of Open Access Journals (Sweden)

    Consuelo de Paiva Godinho COSTA

    2015-06-01

    Full Text Available We propose to make a brief review on nasalization phenomena studies in Portuguese, aiming the phonological process of nasal harmonization that occurs in the variety of Brazilian Portuguese spoken in Vitória da Conquista-BA and region, a phenomenon hitherto not described for any Portuguese dialect. To do so, we consider as fundamental, D’Angelis (2002 analysis, which incorporates relevant concepts presented by Trubetzkoy, from the Prague School, and some points of Camara Jr. propose. We also propose to update the discussion with the approaches along the lines of auto segmental phonology, incorporating some insights of Piggott (1992, discussing with other analyzes for nasalization phenomena in other languages, especially Guarani (language of Tupi-Guarani Linguistic Family, as proposed by Costa (2010, which deals with the phonological processes involving nasality and nasal harmony in Brazilian indigenous languages , in order to verify if the researches on nasality phenomena in other languages can shed some light on the processes that occur in Portuguese.

  10. Dr. von Braun Briefing Walt Disney

    Science.gov (United States)

    1965-01-01

    Dr. von Braun began his association with Walt Disney in the 1950s when the rocket scientist appeared in three Disney television productions related to the exploration of space. Years later, Dr. von Braun invited Disney and his associates to tour the Marshall Space Flight Center (MSFC) in Huntsville, Alabama. This photograph is dated April 13, 1965. From left are R.J. Schwinghamer from the MSFC, Disney, B.J. Bernight, and Dr. von Braun.

  11. Status reports on the development and application of acoustic emission analysis. Proceedings; Statusberichte zur Entwicklung und Anwendung der Schallemissionsanalyse. Beitraege

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2017-08-01

    The colloquium lectures represent the wide range of applications in acoustic emission analysis and testing in the areas of damage development and damage mechanisms, testing of components, condition monitoring, development of new measuring systems and sensors as well as software development regarding locating methods and signal analysis. One focus of the colloquium is on current hardware and software developments for status monitoring by means of AE monitoring. One of the papers was separately analyzed for this database. [German] Die Vortraege des Kolloquiums repraesentieren das breite Spektrum der Anwendungen der Schallemissionsanalyse und -pruefung in den Bereichen der Schadensentwicklung und Schadensmechanismen, Pruefung von Bauteilen, Zustandsueberwachung, Entwicklung neuer Messsysteme und Sensoren sowie Softwareentwicklung bezueglich Ortungsverfahren und Signalanalyse. Ein Schwerpunkt des Kolloquiums betrifft aktuelle Hard- und Softwareentwicklungen zur Zustandsueberwachung durch AE-Monitoring.

  12. The potential of profiled steel sheet deck systems in reference to passive cooling strategies; Der Beitrag von Profilblechdecken zur passiven Kuehlung

    Energy Technology Data Exchange (ETDEWEB)

    Doering, Bernd; Feldmann, Markus; Kuhnhenne, Markus [RWTH Aachen (Germany). Lehrstuhl fuer Stahlbau und Leichtmetallbau

    2009-04-15

    The use of the thermal inertia of building components to improve the indoor temperature and to reduce the energy consumption was covered in various research projects in the past. Generally, thermal building simulation tools (TRNSYS, TAS, e.g.) are used for the assessment of the effect of thermal inertia, and also the current version of the standard DIN V 18599 takes the effect of the heat capacity of the affected surfaces. Both, DIN V 18599 and thermal building simulation tools, assume a one-dimensional characterization of walls and flooring systems, that means they are assembled based on plane layers. This approach is not valid for inhomogeneous components like profiled steel sheet deck systems. In this report thermal equivalent values for such elements are developed, based on the analysis of transient Finite Element Calculations (FEM), thus the one-dimensional are suitable using these equivalent properties. For a selection of available profiles the effect of such deck systems referring heat-intake and heat-disposal was investigated. (Abstract Copyright [2009], Wiley Periodicals, Inc.) [German] Die Ausnutzung der thermischen Speichermasse eines Gebaeudes zur Beeinflussung der Raumtemperaturen bzw. zur Reduzierung des Energieverbrauchs war in der Vergangenheit Gegenstand zahlreicher Forschungsvorhaben. Um den Einfluss der Speichermasse ermitteln zu koennen, werden haeufig thermische Gebaeudesimulationsprogramme eingesetzt, aber auch die aktuelle Fassung von DIN V 18599 beruecksichtigt die Wirkung der Waermekapazitaet der raumumfassenden Flaechen. Sowohl bei Anwendung von DIN V 18599 als auch bei der Gebaeudesimulation geht man dabei von einer eindimensionalen Schichtenfolge fuer Waende und Decken aus. Es gibt jedoch Bauteile, wie z. B. Profilblechdecken, bei denen diese Annahme nicht zutreffend ist. In diesem Bericht werden nun ueber die Auswertung dynamischer FEM-Berechnungen fuer inhomogene Deckenaufbauten Ersatzgroessen bestimmt, so dass die Definition einer

  13. Laser beam welding of high strength aluminium-lithium alloys; Laserstrahlschweissen von hochfesten Aluminium-Lithium Legierungen

    Energy Technology Data Exchange (ETDEWEB)

    Enz, Josephin

    2012-07-01

    The present development in aircraft industry determined by the demand for a higher cost-effectiveness. Laser beam welding is one of the most promising joining technologies for the application in the aircraft industry through the considerable reduction of the production costs. Furthermore the weight of an aircraft structure can be reduced by the use of light and high strength aluminium alloys. This paper deals with the development of a process for the laser beam welding of a skin-stringer-joint where the Al-Li-alloy AA2196 is used as stringer material and the Al-Li-alloy AA2198 is used as skin and stringer material. By the use of design of experiments the optimal welding process parameters for different material combinations were determined which will be used for the welding of a 5-stringer panel. Therefore the weld seams of the joints were tested for irregularities and microstructural characteristics. In addition several mechanical tests were performed, which define the quality of the welded joint. Furthermore the influence of the oxide layer and the welding preparation on the welding performance was investigated. (orig.) [German] Die derzeitigen Entwicklungen im Flugzeugbau werden durch die allgemeine Forderung nach einer Steigerung der Wirtschaftlichkeit bestimmt. Das Laserstrahlschweissen ist dabei eines der vielversprechendsten Fuegeverfahren fuer die Anwendung im Flugzeugbau durch das die Herstellungskosten deutlich reduziert werden koennen. Zudem kann durch die Verwendung von leichten und hochfesten Aluminium-Legierungen das Gewicht einer Flugzeugstruktur zusaetzlich reduziert werden. Die vorliegende Arbeit befasst sich mit der Entwicklung eines Prozesses zum Laserstrahlschweissen einer Skin-Stringer-Verbindung aus den Aluminium-Lithium-Legierungen AA2196 (als Stringer-Werkstoff) und AA2198 (als Skin- und Stringer-Werkstoff). Unter Verwendung der statistischen Versuchsplanung wurden die optimalen Einstellungen der Schweissprozessparameter fuer die

  14. Reflexionseigenschaften von Windenergieanlagen im Funkfeld von Funknavigations- und Radarsystemen

    Science.gov (United States)

    Sandmann, S.; Divanbeigi, S.; Garbe, H.

    2015-11-01

    Die hier behandelte Untersuchung befasst sich mit den Störungen des elektrischen Feldes einer Doppler Very High Frequency Omnidirectional Radio Range Navigationsanlage (DVOR) in der Gegenwart von Windenergieanlagen (WEA). Hierfür wird die Feldstärke auf 25 konzentrischen Kreisbahnen, sog. Orbit Flights verschiedener Höhen und mit verschiedenen Radien rund um die DVOR-Anlage numerisch simuliert. Insbesondere werden die Einflüsse diverser Parameter der WEA wie deren Anzahl, Position, Rotorwinkel, Turmhöhe und Rotordurchmesser auf die Feldverteilung herausgestellt, sowie die Anwendbarkeit der Simulationsmethode Physical Optics (PO) durch Vergleich der Simulationsergebnisse mit denen der Multi Level Fast Multipol Method (MLFMM) untersucht.

  15. Correlations of nasal responses to leukotriene D4 and histamine nasal provocation with quality of life in allergic rhinitis

    Science.gov (United States)

    Zhu, Zheng; Xie, Yanqing; Guan, Weijie; Gao, Yi; Xia, Shu; Shi, Xu

    2016-01-01

    Background The symptoms of allergic rhinitis (AR) greatly affect the quality of life (QoL) in the patients with AR. The correlations of nasal response to leukotriene D4 (LTD4) and histamine nasal provocation with health related QoL in AR are not clear. Objective To evaluate the correlations of nasal response to LTD4 and histamine nasal challenge with QoL in AR. Methods Patients randomly underwent LTD4 and histamine nasal challenge tests, completed the rhinoconjunctivitis quality of life questionnaire (RQoLQ), and rating the symptom severity score (total symptom score 4, TSS4) in the previous week. The correlations between nasal challenge tests induced nasal responses and QoL in RQoLQ were analyzed. Results A total of 25 eligible AR patients enrolled and finished both LTD4 and histamine nasal challenge and completed the questionnaire of RQoLQ. Histamine nasal challenge induced sneezing, increased nasal resistant were correlated with most of the dimensions (general, practical, nasal, eye problems, and quality of sleep, p < 0.05), while LTD4 nasal challenge induced sneeze, increased nasal resistant only correlated with nasal and ocular problems. On the contrary, the severity of the sneeze assessed by TSS4, was not correlated with QoL, while the severity of rhinorrhea, congestion, and nasal pruritus were correlated with nasal and practical problems, and nasal congestion was also correlated with ocular problems (r = 0.60, p = 0.01). Conclusion LTD4 and histamine nasal challenge induced nasal responses were correlated with different clinical symptoms severity and QoL, which can be used as a good diagnosis and evaluation methods for the management of AR.

  16. Nasal meatus plasty: a contribution to plastic reconstruction of the nasal valve during midfacial degloving

    Directory of Open Access Journals (Sweden)

    Lorenz, Kai J.

    2014-05-01

    Full Text Available Midfacial degloving is a proven method for easily accessing the midface, the nasal pyramid, the maxillary and ethmoidal sinuses, the orbits, as well as the anterior skull base. Indications for this method of access mainly include tumour resections in the area of the midface, the septum, the maxillary sinus, the paranasal to the sphenoidal sinus as well as the clivus. In addition, this method of access allows for the exposure of the bony structures of the midface in the event of extensive fractures.In general, this method of access combines an incision in the oral vestibule and circular incisions in the nasal vestibule area in order to release the nasal pyramid.After removing the facial wall of the maxillary sinus, extensive exposure of the surgical site is possible.One disadvantage of this method of access is the difficult reconstruction of the nasal valve area, which often leads to cicatricial stenoses and difficulties with breathing through the nose. Furthermore, wound healing problems and osteoradionecrosis in the area of the lateral margin of the anterior nasal aperture after replantation of the facial wall of the maxillary sinus have been described, because in this area sufficient soft tissue coverage cannot be ensured when a conventional technique is used.We describe a soft tissue flap pedicled in the cranial and caudal directions in the nasal valve area which makes both the reconstruction of the nasal vestibule and sufficient soft tissue coverage of the anterior nasal aperture possible.

  17. Válvula nasal: anatomia e fisiologia Nasal valve: anatomy and physiology

    Directory of Open Access Journals (Sweden)

    Carlos Eduardo Nazareth Nigro

    2009-04-01

    Full Text Available A porção anterior das cavidades nasais, da narina à válvula nasal (VN, é a região de maior resistência nasal ao fluxo aerífero, de suma importância para a fisiologia nasal. Na literatura existem terminologias diferentes para se referir às mesmas estruturas anatômicas e, ainda, o mesmo termo se referindo a estruturas anatômicas diferentes. OBJETIVO: Realizamos este trabalho com o objetivo de revisarmos o funcionamento da VN e definirmos com mais clareza estruturas anatômicas da porção anterior das cavidades nasais, principalmente a região da VN. CONCLUSÃO: Existe controvérsia na literatura quanto à nomenclatura das estruturas da VN. Neste trabalho definimos VN como uma estrutura tridimensional compreendida anteriormente pelo ostium internum e posteriormente pelo isthmus nasi.The anterior portion of the nasal cavities, from the nostril to the nasal valve (NV, is the place of highest nasal resistance to airflow, paramount to nasal physiology. There are different terminologies for the same anatomic structures in the literature. AIM: The aim of this paper was to study the NV function and define clearly the structures of the anterior portion of the nasal cavities, mainly the region of the NV. CONCLUSION: Internum ostium is the anterior segment and isthmus nasi is the posterior segment of the NV region.

  18. Triclosan promotes Staphylococcus aureus nasal colonization.

    Science.gov (United States)

    Syed, Adnan K; Ghosh, Sudeshna; Love, Nancy G; Boles, Blaise R

    2014-04-08

    The biocide triclosan is used in many personal care products, including toothpastes, soaps, clothing, and medical equipment. Consequently, it is present as a contaminant in the environment and has been detected in some human fluids, including serum, urine, and milk. Staphylococcus aureus is an opportunistic pathogen that colonizes the noses and throats of approximately 30% of the population. Colonization with S. aureus is known to be a risk factor for several types of infection. Here we demonstrate that triclosan is commonly found in the nasal secretions of healthy adults and the presence of triclosan trends positively with nasal colonization by S. aureus. We demonstrate that triclosan can promote the binding of S. aureus to host proteins such as collagen, fibronectin, and keratin, as well as inanimate surfaces such as plastic and glass. Lastly, triclosan-exposed rats are more susceptible to nasal colonization with S. aureus. These data reveal a novel factor that influences the ability of S. aureus to bind surfaces and alters S. aureus nasal colonization. IMPORTANCE Triclosan has been used as a biocide for over 40 years, but the broader effects that it has on the human microbiome have not been investigated. We demonstrate that triclosan is present in nasal secretions of a large portion of a test population and its presence correlates with Staphylococcus aureus nasal colonization. Triclosan also promotes the binding of S. aureus to human proteins and increases the susceptibility of rats to nasal colonization by S. aureus. These findings are significant because S. aureus colonization is a known risk factor for the development of several types of infections. Our data demonstrate the unintended consequences of unregulated triclosan use and contribute to the growing body of research demonstrating inadvertent effects of triclosan on the environment and human health.

  19. Planung von CLIL-Unterricht

    Directory of Open Access Journals (Sweden)

    Josef Leisen

    2015-10-01

    Full Text Available Der Beitrag formuliert die Sprachlernbedingungen und die Leitlinien des Sprachlernens im Fach und nennt Merkmale des guten integrierten Fach- und Sprachlehrens. Ausgehend von den Sprachproblemen, die sich im CLIL-Unterricht auftun, wird der sprachsensible CLIL-Unterricht definiert, und es werden Anregungen zur Gestaltung gegeben. Sprachliche Standardsituationen umfassen die kommunikativen Situationen im CLIL-Unterricht, die beim fachlichen Lernen auftreten und von der CLIL-Lehrkraft professionell bewältigt werden müssen. Im Beitrag wird ein Lehr-Lern-Modell ausführlich beschrieben und erläutert. Die Steuerungen von Sprachlernprozessen im CLIL durch Aufgabenstellungen, Methoden-Werkzeuge, Moderation und Diagnose/Rückmeldung werden ausführlich beschrieben. Die Planung einer Lernlinie in sechs Schritten wird dargestellt und erläutert. Planungsraster für CLIL-Lernlinien schließen den Beitrag ab. The article sets out the conditions for language learning in general as well as guiding principles of language learning in the subject and puts forward criteria for successfully integrated content and language learning. Based on typical language problems arising in CLIL-classrooms, the language-sensitive CLIL-classroom is defined and organisational suggestions are given. Linguistic standard situations comprise the communicative situations in the CLIL-classroom which are encountered in subject-related learning and have to be professionally mastered by the CLIL-teacher. The article extensively describes and explains a model of teaching and learning that can be used for the CLIL-classroom. It gives detailed information on managing language learning processes in CLIL by means of tasks, resources and methods as well as discourse facilitation, evaluation and feedback. In addition, a six-step lesson unit is outlined and explained. The article concludes by giving a planning matrix for CLIL lesson units.

  20. Development of a physiologically relevant dripping analytical method using simulated nasal mucus for nasal spray formulation analysis

    Directory of Open Access Journals (Sweden)

    Tina Masiuk

    2016-10-01

    Full Text Available Current methods for nasal spray formulations have been elementary evaluating the dripping characteristics of a formulation and have not assessed the behavior of the nasal formulation in the presence of varying types of mucus depending on the indication or diseased state. This research investigated the effects of nasal mucus on the dripping behavior of nasal formulations and focused on developing an improved in vitro analytical test method that is more physiologically relevant in characterizing nasal formulation dripping behavior. Method development was performed using simulated nasal mucus preparations for both healthy and diseased states as coatings for the dripping experiment representing a wide range of viscosity. Factors evaluated during development of this in vitro test method included amount of mucus, application of mucus, drying times, and compatibility of the mucus on a C18 Thin Layer Chromatography (TLC substrate. The dripping behavior of nasal formulations containing a range of 1% Avicel to 3.5% Avicel was assessed by actuating the nasal spray on a perpendicular TLC plate coated with either healthy or diseased simulated nasal mucus. After actuation of the nasal spray, the dripping of the formulation on the coated TLC plate was measured after the plate was repositioned vertically. The method that was developed generated reproducible results on the dripping behavior of nasal formulations and provided critical information about the compatibility of the formulation with the nasal mucus for different diseased states, aiding in nasal spray formulation development and physical characterization of the nasal spray.

  1. Development of a physiologically relevant dripping analytical method using simulated nasal mucus for nasal spray formulation analysis$

    Institute of Scientific and Technical Information of China (English)

    Tina Masiuk n; Parul Kadakia; Zhenyu Wang

    2016-01-01

    Current methods for nasal spray formulations have been elementary evaluating the dripping char-acteristics of a formulation and have not assessed the behavior of the nasal formulation in the presence of varying types of mucus depending on the indication or diseased state. This research investigated the effects of nasal mucus on the dripping behavior of nasal formulations and focused on developing an improved in vitro analytical test method that is more physiologically relevant in characterizing nasal formulation dripping behavior. Method development was performed using simulated nasal mucus preparations for both healthy and diseased states as coatings for the dripping experiment representing a wide range of viscosity. Factors evaluated during development of this in vitro test method included amount of mucus, application of mucus, drying times, and compatibility of the mucus on a C18 Thin Layer Chromatography (TLC) substrate. The dripping behavior of nasal formulations containing a range of 1%Avicel to 3.5%Avicel was assessed by actuating the nasal spray on a perpendicular TLC plate coated with either healthy or diseased simulated nasal mucus. After actuation of the nasal spray, the dripping of the formulation on the coated TLC plate was measured after the plate was repositioned vertically. The method that was developed generated reproducible results on the dripping behavior of nasal formula-tions and provided critical information about the compatibility of the formulation with the nasal mucus for different diseased states, aiding in nasal spray formulation development and physical characterization of the nasal spray.

  2. Professional little helpers. PHOTON has tested thermography cameras for use in solar sector; Professionelle Helferlein. PHOTON hat Thermografiekameras fuer die Anwendung im Solarbereich getestet

    Energy Technology Data Exchange (ETDEWEB)

    Hinz, Juliane; Kreutzmann, Anne; Siemer, Jochen

    2013-05-15

    The PHOTON Lab has tested again thermography cameras. Eight of the 14 tested cameras reached the ''good'' rating. The three test winner come from two German producers (Testo 885, Testo 876, Flir Systems E60). [German] Das PHOTON-Labor hat erneut Thermographiekameras getestet. Von den 14 getesteten Kameras erreichten acht die Note ''gut''. Die drei Testsieger stammen von zwei deutschen Herstellern (Testo 885, Testo 876, Flir Systems E60).

  3. Anwendung der geoelektrischen 3D-Tomographie für die Analyse thermisch induzierter Strömungen im Labor

    OpenAIRE

    2008-01-01

    Sowohl in der Natur als auch in der Industrie existieren thermisch induzierte Strömungen. Von Interesse für diese Forschungsarbeit sind dabei die Konvektionen im Erdmantel sowie in den Glasschmelzwannen. Der dort stattfindende Materialtransport resultiert aus Unterschieden in der Dichte, der Temperatur und der chemischen Konzentration innerhalb des konvektierenden Materials. Um das Verständnis für die ablaufenden Prozesse zu verbessern, werden von zahlreichen Forschergruppen numerische Modell...

  4. Walt Disney and Dr. Wernher von Braun

    Science.gov (United States)

    1954-01-01

    Dr. Werhner von Braun, then Chief, Guided Missile Development Operation Division at Army Ballistic Missile Agency (ABMA) in Redstone Arsenal, Alabama, was visited by Walt Disney in 1954. In the 1950's, von Braun worked with Disney Studio as a technical director, making three films about space exploration for television. A model of the V-2 rocket is in background.

  5. Von Neumann Was Not a Quantum Bayesian

    CERN Document Server

    Stacey, Blake C

    2014-01-01

    Wikipedia has claimed for over two years now that John von Neumann was the "first quantum Bayesian." In context, this reads as stating that von Neumann inaugurated QBism, the approach to quantum theory promoted by Fuchs, Mermin and Schack. This essay explores how such a claim is, historically speaking, unsupported.

  6. Kultuuriakadeemias saab kaeda Von Krahli ime tabamist

    Index Scriptorium Estoniae

    2006-01-01

    Marianne Kõrver, Jaak Kilmi, Andres Maimik, Marko Raat, Rainer Sarnet ja Arbo Tammiksaar tegid Eduard Vilde näidendist "Tabamata ime" kuus lühimängufilmi Von Krahli teatris ettekandmiseks. 25. mail tuleb Von Krahli Teater Viljandisse ja näitab teatrifilmi Kultuuriakadeemias

  7. Mixing subalgebras of finite von Neumann algebras

    CERN Document Server

    Cameron, Jan; Mukherjee, Kunal

    2010-01-01

    Jolissaint and Stalder introduced the definitions of mixing and weak mixing for von Neumann subalgebras of finite von Neumann algebras. In this paper, we study various algebraic and analytical properties of mixing and weakly mixing von Neumann subalgebras. We prove some basic results about mixing inclusions of von Neumann algebras and establish a connection between mixing properties and normalizers of von Neumann subalgebras. The special case of mixing subalgebras arising from inclusions of group von Neumann algebras finds applications to ergodic theory. For a finite von Neumann algebra $M$ and von Neumann subalgebras $A$, $B$ of $M$, we introduce a notion of weak mixing of $B\\subseteq M$ relative to $A$. If $B$ is abelian and $A\\subset B$, we show that weak mixing of $B \\subset M$ relative to $A$ is equivalent to the following property: if $x\\in M$ and $xAx^*\\subset B$ then $x\\in B$. In the general case, we show that weak mixing of $B\\subset M$ relative to $A$ is equivalent to the following property: if $x\\i...

  8. Ludwig von Mises: An Annotated Bibliography.

    Science.gov (United States)

    Gordon, David

    A 117-item annotated bibliography of books, articles, essays, lectures, and reviews by economist Ludwig von Mises is presented. The bibliography is arranged chronologicaly, and is followed by an alphabetical listing of the citations, excluding books. An index and information on the Ludwig von Mises Institute at Auburn University (Alabama) are…

  9. Anwendung der extrakorporalen Stoßwellentherapie bei kalzifizierender Periathropathia humeroscapularis, Fersensporn und Epicondylitis humeri - Erfahrungsbericht aus dem Wilhelminenspital

    Directory of Open Access Journals (Sweden)

    Feyertag J

    2004-01-01

    Full Text Available Die Stoßwellentherapie wird bei verschiedenen Indikationen, die unter konservativen Therapien schwer zu schwer zu behandeln sind, eingesetzt. Dazu zählen die kalzifizierenden Schultererkrankungen (Tendinitis calcarea, Epicondylitis humeri (EHR und die plantare Fasciitis mit/ohne plantarem Fersensporn (FSP. Berichtet werden die Ergebnisse von 147 Patienten (102 Frauen/45 Männer, mittleres Alter betrug 57,8 Jahre, die mittels einer einmaligen extrakorporalen Stoßwellentherapie (ESWT (Tend. calc. 82 %, FSP 11 % oder EHR 7 % mittels eines HMT-ReflecTron therapiert wurden. Verabreicht wurden im Mittel 1.800 Stoßwellen. Untersucht wurde die subjektive Verbesserung der Schmerzen anhand einer visuellen Analogskala vor und 6 Wochen nach der Therapie bei allen Patienten. Bei Patienten mit Tendinitis calcarea wurde auch eine Verbesserung der Funktion sowie Veränderungen der Kalzifizierungen untersucht. Bei allen Patienten konnte eine statistisch signifikante Verbesserung der Schmerzen sowie des Bewegungsumfanges beobachtet werden (p 0,0001. Röntgenaufnahmen ergaben eine partielle Verkleinerung der Kalkdepots bei ca. 80 % der Patienten. Aufgrund der geringen Zahl der Patienten fand sich für die EHR keine signifikante Verbesserung der Schmerzsymptomatik. Eine einmalige ESWT kann zu einer deutlichen Verbesserung der Schmerzsymptomatik und zu einer Verbesserung des Bewegungsumfanges führen. Bei 80 % der Patienten mit einer Tendinitis calcarea findet sich weiter eine partielle Verkleinerung der Kalkdepots 6 Wochen nach Therapie.

  10. Application of Bayes Kriging assessment method for deposits modelling; Eine Anwendung des Bayes Kriging in der Lagerstaettenmodellierung

    Energy Technology Data Exchange (ETDEWEB)

    Pilz, J. [Inst. fuer Mathematik, Statistik und Didaktik der Mathematik, Univ. Klagenfurt (Austria); Knospe, S. [Inst. fuer Markscheidewesen und Geodaesie, TU Bergakademie Freiberg (Germany)

    1997-12-01

    Because of accessibility problems, the assessment (interpolation) of an area of deposits requires mathematical and statistical methods designed to evaluate those parameters which determine the quality and quantity of the contents. Statistical evaluations of this type are usually based solely on the results of exploratory boreholes. This paper shows how, when assessing borehole data from an area of deposits, geoscientific knowledge can be incorporated into the geostatic evaluation in order to improve the accuracy and plausibility of the calculation results. The Bayes Kriging assessment method described here provides geologists and assayers with a practical and reliable tool for analysing exploration data which allows various qualitative and quantitative information to be included in the data handling process and which can assist in the subsequent interpretation of results. As well as increasing plausibility, the new tool produces calculation errors which are smaller than those of other calculation systems. (orig.) [Deutsch] Der in der Erkundung arbeitende Geologe oder Rohstoffwirtschaftler erhaelt mit der hier vorgestellten Bayes-Kriging-Schaetzung ein praktikables und erfolgversprechendes Werkzeug fuer die Auswertung von Erkundungsdaten, das die Einbeziehung verschiedener qualitativer und quantitativer Zusatzinformationen in die Datenauswertung ermoeglicht und bei der Interpretation der Ergebnisse hilfreich sein kann. (orig.)

  11. Silver nasal sprays: misleading Internet marketing.

    Science.gov (United States)

    Gaslin, Michael T; Rubin, Cory; Pribitkin, Edmund A

    2008-04-01

    Long-term use of silver-containing products is associated with a permanent bluish-gray discoloration of the skin known as argyria, but they remain widely available despite several measures by the FDA to regulate them. Several recent case reports have described the occurrence of argyria as a result of using these "natural" products. We used the five most common Internet search engines to find Web sites providing information on silver-containing nasal sprays. Of 49 Web sites analyzed, only 2 (4%) mentioned argyria as a possible complication, although 30 (61%) did caution against long-term use. Eight sites (16%) made specific claims about the health benefits of the product. All 49 sites (100%) provided direct or indirect links to buy silver-containing nasal sprays. We conclude that information about silver-containing nasal sprays on the Internet is misleading and inaccurate. Therefore, otolaryngologists should be aware of the misinformation their patients may be receiving about these products.

  12. Discriminating between Nasal and Mouth Breathing

    CERN Document Server

    Curran, Kevin; Coyle, Damian

    2010-01-01

    The recommendation to change breathing patterns from the mouth to the nose can have a significantly positive impact upon the general well being of the individual. We classify nasal and mouth breathing by using an acoustic sensor and intelligent signal processing techniques. The overall purpose is to investigate the possibility of identifying the differences in patterns between nasal and mouth breathing in order to integrate this information into a decision support system which will form the basis of a patient monitoring and motivational feedback system to recommend the change from mouth to nasal breathing. Our findings show that the breath pattern can be discriminated in certain places of the body both by visual spectrum analysis and with a Back Propagation neural network classifier. The sound file recoded from the sensor placed on the hollow in the neck shows the most promising accuracy which is as high as 90%.

  13. Nasal birth trauma: a review of appropriate treatment.

    LENUS (Irish Health Repository)

    Cashman, E C

    2012-02-01

    The aetiology of nasal deformity has frequently included birth trauma. There is no consensus in the literature as to whether nasal surgery, in the form of closed reduction, is indicated in neonates. The majority of studies in the literature that advocate intervention have inadequate followup periods and there is a paucity of evidence for the adverse effects of conservative management. This case highlights the therapeutic dilemma posed by such nasal injuries in the neonate and, to the best of the authors\\' knowledge, at the time of writing, represents the earliest reported case in the literature of nasal deformity in the neonate. The term nasal deformity is used to denote deformity of the nasal pyramid, soft tissue, and septum. Three main aspects of neonatal nasal deformity are addressed including, firstly, if nasal deformity at birth needs to be addressed, secondly, if left unaltered, what the long-term effects are and, finally, if intervention alters the normal course of midfacial development.

  14. Nanoparticles for nasal delivery of vaccines : monitoring adaptive immune responses

    NARCIS (Netherlands)

    Keijzer, C.

    2013-01-01

    The continuous emergence of new pathogens and growing drug resistance of microorganisms asks for innovative vaccination strategies. An alternative to conventional multiple injection vaccines is the nasal route of vaccine delivery. The immune response induced following nasal antigen delivery depends

  15. PHONETIC EVIDENCE FOR THE NASAL CODA SHIFT IN MANDARIN

    Directory of Open Access Journals (Sweden)

    James H. Yang

    2010-06-01

    Full Text Available This paper presented phonetic evidence to resolve the transcription disagreement concerning the syllable-final nasal shift in the variety of Mandarin spoken in Taiwan. Although three judges agreed that the rhyme /iŋ/ underwent a sound change, they perceived the nasal coda shift differently. Two of them transcribed it as a modification from /iŋ/ to /in/, whereas the other asserted that the velar nasal disappears with its preceding vowel nasalized. In order to resolve this transcription conflict, this study analyzed the acoustic attributes of the speculative sound alterations in question, including /in/, /iŋ/, /i/ and /ĩ/. The phonetic analysis indicated that the Taiwanese participants did not nasalize the preceding vowel deleting the nasal coda but tended to pronounce the post-vocalic velar nasal as its dental counterpart. This study concluded by discussing the implications of the synchronic variation for the theories of the nasal coda shift in Chinese dialects.

  16. Nasal Birth Trauma: A Review of Appropriate Treatment

    Directory of Open Access Journals (Sweden)

    E. C. Cashman

    2010-01-01

    Full Text Available The aetiology of nasal deformity has frequently included birth trauma. There is no consensus in the literature as to whether nasal surgery, in the form of closed reduction, is indicated in neonates. The majority of studies in the literature that advocate intervention have inadequate followup periods and there is a paucity of evidence for the adverse effects of conservative management. This case highlights the therapeutic dilemma posed by such nasal injuries in the neonate and, to the best of the authors' knowledge, at the time of writing, represents the earliest reported case in the literature of nasal deformity in the neonate. The term nasal deformity is used to denote deformity of the nasal pyramid, soft tissue, and septum. Three main aspects of neonatal nasal deformity are addressed including, firstly, if nasal deformity at birth needs to be addressed, secondly, if left unaltered, what the long-term effects are and, finally, if intervention alters the normal course of midfacial development.

  17. Condrossarcoma nasal: relato de caso

    Directory of Open Access Journals (Sweden)

    Pinna Fábio de Rezende

    2003-01-01

    Full Text Available O condrossarcoma é uma neoplasia maligna proveniente de tecido cartilaginoso, cuja incidência em região de cabeça e pescoço é rara. É mais freqüente em pacientes do sexo masculino, entre a terceira e quarta décadas, e na face localiza-se no seio e osso maxilar, sendo raro no septo nasal. Esse relato descreve o caso de uma paciente do sexo feminino, de 13 anos de idade, que apresentava queixa de deformidade facial em região malar direita acompanhada de dores esporádicas. Ao exame físico apresentava um abaulamento de aproximadamente 3 cm de diâmetro em região malar esquerda, não sendo notada nenhuma alteração à rinoscopia anterior. Foram realizadas tomografia computadorizada (TC de seios paranasais, ressonância magnética de face e biópsia da lesão para estudo anatomopatológico, que inicialmente sugeria o diagnóstico de condroma. Após a exérese da massa, a paciente evoluiu com recidiva da lesão em apenas 5 meses. Diante deste fato surpreendente, foi requisitada a revisão da lâmina que evidenciou Condrossarcoma tipo I. Nova cirurgia foi realizada, visando a remoção do tumor, com tratamento radioterápico complementar. Atualmente, a paciente se encontra em acompanhamento ambulatorial, sem queixas álgicas e sem sinas de recidiva. Os condrossarcomas são tumores malignos de crescimento lento, mas localmente agressivos, tendo grande propensão a recidivas. A conduta é preferencialmente cirúrgica, uma vez que são pouco radiossensíveis e a quimioterapia é meramente paliativa. O objetivo deste estudo é apresentar um caso de condrossarcoma em seio maxilar, etmóide, esfenóide e septo, discutindo o quadro clínico, diagnóstico, fatores prognósticos e conduta.

  18. Bilateral Nasoalveolar Cyst Causing Nasal Obstruction

    Directory of Open Access Journals (Sweden)

    Uzeyir Yildizoglu

    2016-01-01

    Full Text Available Nasoalveolar cysts, which originate from epithelial remnants of nasolacrimal duct, are nonodontogenic soft tissue lesions of the upper jaw. These cysts are thought to be developmental and are presented with fullness in the upper lip and nose, swelling on the palate, and sometimes nasal obstruction. Because of cosmetic problems, they are often diagnosed at an early stage. These lesions are mostly revealed unilaterally but also can be seen on both sides. In this case report, a patient who complained of nasal obstruction and then diagnosed with bilateral nasoalveolar cysts and treated by sublabial excision is presented and clinical features and treatment approaches are discussed with the review of literature.

  19. Bilateral Nasoalveolar Cyst Causing Nasal Obstruction

    Science.gov (United States)

    Yildizoglu, Uzeyir; Polat, Bahtiyar; Durmaz, Abdullah

    2016-01-01

    Nasoalveolar cysts, which originate from epithelial remnants of nasolacrimal duct, are nonodontogenic soft tissue lesions of the upper jaw. These cysts are thought to be developmental and are presented with fullness in the upper lip and nose, swelling on the palate, and sometimes nasal obstruction. Because of cosmetic problems, they are often diagnosed at an early stage. These lesions are mostly revealed unilaterally but also can be seen on both sides. In this case report, a patient who complained of nasal obstruction and then diagnosed with bilateral nasoalveolar cysts and treated by sublabial excision is presented and clinical features and treatment approaches are discussed with the review of literature. PMID:27980871

  20. The Fungi Flora of Healthy Nasal Mucosa in Kerman, Iran

    OpenAIRE

    2011-01-01

    Introduction: Environmental fungi, molds and yeasts, can infest the nasal cavity through inhaled air. There is some evidence that they could be the main cause of Chronic Rhinosinusitis (CRS) but little is known about the normal fungal flora in the human nose. The objective of this study was to assess the normal fungal flora of the nasal mucus in adults in Kerman. Materials and Methods: We conducted a cross sectional study. Nasal swabs were used to sample the nasal cavity of 100 a...

  1. STRATEGIES AND PROSPECTS OF NASAL DRUG DELIVERY SYSTEMS

    OpenAIRE

    Gannu Praveen Kumar

    2012-01-01

    The recent advancement of nasal drug delivery systems has increased enormously and is gaining significant importance. Intranasal therapy has been an accepted form of treatment in the Ayurvedic system of Indian Medicine. The non-invasive delivery of nasal drug delivery systems made to exploit for the development of successful treatment. The advantages, disadvantages, mechanism of action and application of nasal drug delivery system in local delivery, systematic delivery, nasal vaccines and CNS...

  2. Intraosseous hemangioma of the nasal septum: A case report

    Energy Technology Data Exchange (ETDEWEB)

    Park, Min Ho; Kim, Eui Jong; Jang, Ji Hye; Lee, Kyung Mi; Choi, Woo Suk; Kim, Sung Wan; Kim, Yoon Hwa [Kyung Hee University Hospital, Seoul (Korea, Republic of)

    2015-08-15

    Hemangioma can arise in the soft tissues and bone of the nasal cavity. However, to the best of our knowledge, there are no prior case reports presenting intraosseous hemangioma of the nasal septum. Intraosseous hemangioma, in addition to a chondroid tumor, should be included in the differential diagnosis of a calcified mass of the nasal cavity. In the present report, we present a case of an intraosseous cavernous hemangioma in the nasal bony septum of a 53-year-old woman.

  3. Investigations of co-combustion of plastics in a coal dust furnace; Untersuchungen zur Mitverbrennung von Kunststoffen in einer Kohlestaubfeuerung

    Energy Technology Data Exchange (ETDEWEB)

    Gerhardt, T.; Spliethoff, H.; Hein, K.R.G. [Stuttgart Univ. (Germany). Inst. fuer Verfahrenstechnik und Dampfkesselwesen (IVD); Christill, M.; Kicherer, A.; Seifert, H. [BASF AG, Verfahrenstechnik-ZET/EH-L544, Ludwigshafen am Rhein (Germany)

    1996-12-31

    schwer entzuendlichen Materials, konnte fuer die IVD-Versuchsbrennkammer in Grenzkornspektrum von 1,25 bis 1,5 mm Partikelgroesse, bei der Verbrennung mit Steinkohle, erreicht werden. Fuer die industrielle Anwendung werden durch die andere Brenneranordnung eher bessere Resultate gegenueber der Versuchsanlage erwartet. (orig)

  4. The NOFLO trial: low-flow nasal prongs therapy in weaning nasal continuous positive airway pressure in preterm infants.

    LENUS (Irish Health Repository)

    O'Donnell, Sinéad M

    2013-07-01

    To determine if low-flow nasal prongs therapy with room air, compared with no treatment, facilitates weaning from nasal continuous positive airway pressure (NCPAP) in very low birth weight (VLBW, birth weight <1500 g) infants.

  5. Underlying Phoneme Velar Nasal with Lip Rounding in Hueyapan Nahuatl

    Science.gov (United States)

    Campbell, R. Joe

    1976-01-01

    Reasons are given for the idea that Hueyapan (Morelos) Nahuatl has an underlying velar nasal with lip rounding phoneme which never has the surface reflex of a rounded velar nasal allophone, but occurs phonetically as a velar nasal allophone or a labial dental voiced allophone or disappears. (SCC)

  6. Underlying Phoneme Velar Nasal with Lip Rounding in Hueyapan Nahuatl

    Science.gov (United States)

    Campbell, R. Joe

    1976-01-01

    Reasons are given for the idea that Hueyapan (Morelos) Nahuatl has an underlying velar nasal with lip rounding phoneme which never has the surface reflex of a rounded velar nasal allophone, but occurs phonetically as a velar nasal allophone or a labial dental voiced allophone or disappears. (SCC)

  7. Staphylococcus aureus and the ecology of the nasal microbiome

    DEFF Research Database (Denmark)

    Liu, Cindy M; Price, Lance B; Hungate, Bruce A

    2015-01-01

    The human microbiome can play a key role in host susceptibility to pathogens, including in the nasal cavity, a site favored by Staphylococcus aureus. However, what determines our resident nasal microbiota-the host or the environment-and can interactions among nasal bacteria determine S. aureus...

  8. NORMAL NASAL GENE EXPRESSION LEVELS USING CDNA ARRAY TECHNOLOGY

    Science.gov (United States)

    Normal Nasal Gene Expression Levels Using cDNA Array Technology. The nasal epithelium is a target site for chemically-induced toxicity and carcinogenicity. To detect and analyze genetic events which contribute to nasal tumor development, we first defined the gene expressi...

  9. Nasal bots...a fascinating world!

    Science.gov (United States)

    Angulo-Valadez, Carlos E; Scholl, Philip J; Cepeda-Palacios, Ramón; Jacquiet, Philippe; Dorchies, Philippe

    2010-11-24

    Larvae causing obligatory myiasis are numerous and they may affect cutaneous and subcutaneous tissues, wounds, nasopharyngeal cavities (nasal bots), internal organs and the digestive tract (bots) of domestic and wild animals and humans as well. Nasal bots belong to the Family Oestridae, Subfamily Oestrinae, which includes several important genera: Oestrus, Kirkioestrus, and Gedoelstia infecting Artiodactyla (except Cervidae) in Africa and Eurasia, Cephenemyia and Pharyngomyia infecting Cervidae, Rhinoestrus infecting horses, Cephalopina infecting camels, Pharyngobolus infecting African elephants, and Tracheomyia infecting Australian kangaroos. Nasal bots are widespread in Mediterranean and tropical areas and in affected animals they induce sneezing and nasal discharge which may become caked with dust making breathing very difficult. The aforementioned species of larvae are host-specific but sometimes the may be deposited in human eyes inducing a painful opthalmomyiasis of short duration. The first fascinating trait of these parasites is the very efficient morphological and biological adaptations to parasitism they show either as larvae or as adults, in order to facilitate their survival and search for a suitable host. Nasal bots have reached different degrees of complexity in their life cycles. Indeed, while for some species (e.g., Oestrus ovis, Rhinoestrus usbekistanicus) larvae are injected by flies directly into nostrils and develop in the sinuses before being ejected for external pupation, some other species migrate from eyes to blood before returning to nasal cavities either through the ethmoid bone (Gedoelstia hässleri) or via lungs and bronchi (Gedoelstia cristata). Moreover, larvae are very well-adapted to their environment being able to undergo through hypobiosis either inside or outside the host, according to the climatic environmental conditions and seasonality. The second fascinating trait of nasal bots is related to host behavioural and immune

  10. Solar power satellites (SPS) and international law. The system of international law governing science and technology projects for energy source development in outer space (Solar power satellites, lunar power systems, Helium-3 project); Solar Power Satellites und Voelkerrecht. Voelkerrechtliche Aspekte von Grossprojekten zur Energiegewinnung aus Weltraumressourcen (Solar Power Satellites, Lunar Power Systems, Helium-3-Projekt)

    Energy Technology Data Exchange (ETDEWEB)

    Will, M.

    2000-07-01

    In addition to the utilization of renewable energy sources on earth, particular interest has been directed since the late 1960s to the exploitation of the energy of the sun via solar power satellites (SPS), and of other energy sources in outer space. The dissertation on hand presents a comprehensive survey and commented analysis, together with an exhaustive bibliography, of the available relevant international laws and treaties and regulatory framework that have been developed by the international legal community since the beginning of the R and D activities and now form the legal system governing the peaceful uses of solar power plants and other energy sources in outer space. The specific legal provisions and their application in the context of existing international laws and treaties are discussed in great depth. (CB) [German] Neben der Nutzung regenerativer Energiequellen auf der Erde ist seit Ende der sechziger Jahre die Errichtung und Nutzung von Solarenergiesatelliten (SPS) von besonderem Interesse. Die Doktorarbeit legt eine umfangreiche, ausfuehrlich erlaeuterte Dokumentation vor ueber die Entwicklung und den derzeitigen Stand von internationalem Recht und Vertraegen, die spezifisch fuer die F und E-Aktivitaeten und die Anwendung der SPS und anderer Energiequellen im Weltraum erforderlich und entwickelt wurden, sowie auch deren Einbettung in und Zusammenwirken mit bestehendem Voelkerrecht und internationalen Vereinbarungen. (CB)

  11. Jacob Stael von Holstein ja palladionism eesti arhitektuuris / Ants Hein

    Index Scriptorium Estoniae

    Hein, Ants, 1952-

    2005-01-01

    Sõjaväeinsenerist ja arhitektist Jacob Stael von Holsteinist (1628, Pärnu-1679), tema kavandatud hoonetest ja rollist 17. sajandi II poole arhitektuuris. Fabian von Ferseni Toompeal Lossiplatsil asunud elamust (lammutati 1894) ja Maardu mõisahoonest, Hans von Ferseni Mäo mõisahoonest Järvamaal, Otto Wilhelm von Ferseni majast Toompeal, Axel von Roseni majast Tallinnas Pikk t. 28 (1670-74), Otto Reinhold von Taube majast Tartus (hävinud), J. S. von Holsteini enda hoonetest: majast Tallinnas Toompea 1, Anija mõisahoonest, elamust Riias jm. Bibliograafia lk. 452

  12. Jacob Stael von Holstein ja palladionism eesti arhitektuuris / Ants Hein

    Index Scriptorium Estoniae

    Hein, Ants, 1952-

    2005-01-01

    Sõjaväeinsenerist ja arhitektist Jacob Stael von Holsteinist (1628, Pärnu-1679), tema kavandatud hoonetest ja rollist 17. sajandi II poole arhitektuuris. Fabian von Ferseni Toompeal Lossiplatsil asunud elamust (lammutati 1894) ja Maardu mõisahoonest, Hans von Ferseni Mäo mõisahoonest Järvamaal, Otto Wilhelm von Ferseni majast Toompeal, Axel von Roseni majast Tallinnas Pikk t. 28 (1670-74), Otto Reinhold von Taube majast Tartus (hävinud), J. S. von Holsteini enda hoonetest: majast Tallinnas Toompea 1, Anija mõisahoonest, elamust Riias jm. Bibliograafia lk. 452

  13. Effect of Local Nasal Immunotherapy on Nasal Blockage in Pollen-Induced Allergic Rhinitis of Guinea Pigs

    OpenAIRE

    Takeshi Nabe; Kayoko Kubota; Nobuaki Mizutani; Masanori Fujii; Tetsuya Terada; Hiroshi Takenaka; Shigekatsu Kohno

    2008-01-01

    Background: As a non-injection route for immunotherapy, local nasal immunotherapy has been examined in allergic rhinitis patients. However, it is unclear how the immunotherapy affects sneezing, biphasic nasal blockage and nasal hyperresponsiveness. Thus, we evaluated the therapeutic effects of nasal immunotherapy on the symptoms of guinea pig allergic rhinitis. Additionally, we also evaluated whether the immunotherapy relieved pollen-induced allergic conjunctivitis. Methods: Sensitized ani...

  14. Differential Kinetics and Distribution of Antibodies in Serum and Nasal and Vaginal Secretions after Nasal and Oral Vaccination of Humans

    OpenAIRE

    Rudin, Anna; Johansson, Eva-Liz; Bergquist, Charlotta; Holmgren, Jan

    1998-01-01

    Although nasal vaccination has emerged as an interesting alternative to systemic or oral vaccination, knowledge is scarce about the immune responses after such immunization in humans. In the present study, we have compared the kinetics and organ distribution of the antibody responses after nasal and oral vaccination. We immunized female volunteers nasally or orally with cholera toxin B subunit (CTB) and determined the specific antibody levels in serum and nasal and vaginal secretions, as well...

  15. [Von Hippel-Lindau syndrome].

    Science.gov (United States)

    Reich, H; Hollwich, F

    1984-06-01

    The von Hippel-Lindau syndrome is an autosomal dominant condition that comprises, apart from angiomas of the retina, the cerebellum, the spinal cord, and the cerebrum, also cystic and blastomatous dysplasias resulting from maldevelopment, namely cystic kidney and pancreas, hypernephroma, and pheochromocytoma. Early observers of the syndrome were the English neurologist John Hughlings Jackson (1872) and the German ophthalmologist Hugo Magnus (1874). The typical association of angiomas of the retina with the cerebellum was first described in 1905 by the Prague ophthalmologist Wilhelm Czermak, long before Lindau (1926). The fact that hypernephromas and pheochromocytomas may form parts of it characterizes the syndrome as a polyneoplastic hereditary disease and the sufferers as members of families at risk. Since the ophthalmologist is often the first to recognize this disease by direct inspection of the fundi, he is responsible for ensuring proper medical care for the affected person and his or her entire family.

  16. The Digital Von Fahrenheid Pyramid

    Science.gov (United States)

    Bura, M.; Janowski, J.; Wężyk, P.; Zięba, K.

    2017-08-01

    3D Scanners Lab from Digital Humanities Laboratory at the University of Warsaw initiated the scientific project, the purpose of which was to call attention to systematically penetrated and devastated pyramid-shaped tomb from the XVIII/XIX century, of family von Fahrenheid in Rapa in Banie Mazurskie commune (NE Poland). By conducting a series of non-invasive studies, such as 3D inventory using terrestrial laser scanning (TLS), thermal imaging, georadar measurements (around and inside the tomb) and anthropological research of mummified remains as well - the complete dataset was collected. Through the integration of terrestrial (TLS) and airborne laser scanning (ALS) authors managed to analyse the surroundings of Fahrenheid pyriamid and influence of some objects (like trees) on the condition and visibility of the Pyramids in the landscape.

  17. Congenital nasal pyriform aperture stenosis: a rare cause of neonatal nasal airway obstruction

    Directory of Open Access Journals (Sweden)

    A Rao

    2015-04-01

    Full Text Available Congenital nasal pyriform aperture stenosis (CNPAS is a rare cause of nasal airway obstruction that clinically mimics choanal atresia in a neonate. The differentiation between the two is very important as the management of the two conditions is different. Timely recognition is important to prevent fatal outcome. CNPAS may present as an isolated condition or with associated craniofacial anomalies. Despite typical findings of CNPAS being present on cross-sectional imaging, this condition is commonly overlooked, probably because of a lack of familiarity with the normal morphological features of the nasal cavity in infants and also owing to a lack of awareness of this rare entity. Here we report a case of CNPAS with pre- and post-surgical CT images and the complication that occurred owing to nasal stenting.

  18. Neues über das Tertiär von Java und die mesozoischen Schichten von West-Borneo

    NARCIS (Netherlands)

    Martin, K.

    1888-01-01

    Die Monographie, welche unter dem Titel Die Fossilien von Java herausgegeben wird ¹), ist so weit fortgeschritten, dass sich aus den in ihr beschriebenen Gastropoden bereits eine Anzahl von Schlussfolgerungen ableiten lässt, welche für die in Bearbeitung begriffene, geologische Karte von Java von

  19. Neues über das Tertiär von Java und die mesozoischen Schichten von West-Borneo

    NARCIS (Netherlands)

    Martin, K.

    1888-01-01

    Die Monographie, welche unter dem Titel Die Fossilien von Java herausgegeben wird ¹), ist so weit fortgeschritten, dass sich aus den in ihr beschriebenen Gastropoden bereits eine Anzahl von Schlussfolgerungen ableiten lässt, welche für die in Bearbeitung begriffene, geologische Karte von Java von Be

  20. Risk factors for nasal malignancies in German men: the South-German Nasal cancer study

    Directory of Open Access Journals (Sweden)

    Greiser Eberhard M

    2012-11-01

    Full Text Available Abstract Background There are few studies of the effects of nasal snuff and environmental factors on the risk of nasal cancer. This study aimed to investigate the impact of using nasal snuff and of other risk factors on the risk of nasal cancer in German men. Methods A population-based case–control study was conducted in the German Federal States of Bavaria and Baden-Württemberg. Tumor registries and ear, nose and throat departments provided access to patients born in 1926 or later. Results Telephone interviews were conducted with 427 cases (mean age 62.1 years and 2.401 population-based controls (mean age 60.8 years. Ever-use of nasal snuff was associated with an odds ratio (OR for nasal cancer of 1.45 (95% confidence interval [CI] 0.88–2.38 in the total study population, whereas OR in smokers was 2.01 (95% CI 1.00-4.02 and in never smokers was 1.10 (95% CI 0.43–2.80. The OR in ever-smokers vs. never-smokers was 1.60 (95% CI 1.24–2.07, with an OR of 1.06 (95% CI 1.05–1.07 per pack-year smoked, and the risk was significantly decreased after quitting smoking. Exposure to hardwood dust for at least 1 year resulted in an OR of 2.33 (95% CI 1.40–3.91 in the total population, which was further increased in never-smokers (OR 4.89, 95% CI 1.92–12.49 in analyses stratified by smoking status. The OR for nasal cancer after exposure to organic solvents for at least 1 year was 1.53 (1.17–2.01. Ever-use of nasal sprays/nasal lavage for at least 1 month rendered an OR of 1.59 (1.04–2.44. The OR after use of insecticides in homes was 1.48 (95% CI 1.04–2.11. Conclusions Smoking and exposure to hardwood dust were confirmed as risk factors for nasal carcinoma. There is evidence that exposure to organic solvents, and in-house use of insecticides could represent novel risk factors. Exposure to asbestos and use of nasal snuff were risk factors in smokers only.

  1. Nasal Functional Evaluation Using Nasal Endoscopy, Acoustic Rhinometry, and Rhinomanometry on Nasal Airway-Obstructed Patients after Endoscopic Septoplasty, Corrective Rhinoplasty, and Internal Nasal Valve Surgery

    Directory of Open Access Journals (Sweden)

    Yiğit Özer Tiftikcioğlu

    2017-06-01

    Full Text Available Objective: Rhinoplasty is a very common surgical procedure that is performed throughout the world as well as in our country for aesthetic concerns, nasal obstruction, or both. However, functional results still remain subjective, and compared to the vast number of operations, studies about functional results in the literature are very limited. The aim of this study is to evaluate respiratory functions after corrective rhinoplasty and to find the benefits both numerically and statistically. Material and Methods: Thirty patients who were admitted to our department with nasal obstruction based on the statements of the patients were included in the study. Patients who were admitted only for aesthetic considerations were excluded from the study. These patients were preoperatively evaluated with radiographic and endoscopic imaging; preoperative nasal resistance and nasal airway cross-sectional area values were measured and recorded with acoustic rhinometry and rhinomanometry devices. Then, patients were operated by open rhinoplasty technique, and measurements were repeated at three months and one year postoperative follow-ups. Results: As a result of measurements made with rhinomanometry one year after the surgery, a decrease in resistance value was observed in 20 patients, and an increase in minimal cross-sectional area measured with acoustic rhinometry was observed in 24 patients. The values measured by both methods were found to be statistically significant. Conclusion: As a result of our study, we advocate performing both functional and aesthetic rhinoplasty operations instead of functional or aesthetic purposes alone.

  2. Squamous cell carcinoma of the nasal vestibule

    DEFF Research Database (Denmark)

    Horsmans, J D; Godballe, C; Jørgensen, K E

    1999-01-01

    From 1978 to 1992, 66 patients (32 women and 34 men) were treated for carcinoma of the nasal vestibule at Odense University Hospital. The treatment was radiotherapy (41 patients), surgery (13 patients) or a combination of the two modalities (12 patients). Twenty-one patients (32%) developed...

  3. High Flow Nasal Cannulae in preterm infants

    Directory of Open Access Journals (Sweden)

    F. Ciuffini

    2013-06-01

    Full Text Available Despite of improved survival of premature infants, the incidence of long term pulmonary complications, mostly associated with ventilation-induced lung injury, remains high. Non invasive ventilation (NIV is able to reduce the adverse effects of mechanical ventilation. Although nasal continuous positive airway pressure (NCPAP is an effective mode of NIV, traumatic nasal complications and intolerance of the nasal interface are common. Recently high flow nasal cannula (HFNC is emerging as an efficient, better tolerated form of NIV, allowing better access to the baby’s face, which may improve nursing, feeding and bonding. The aim of this review is to discuss the available evidence of effectiveness and safety of HFNC in preterm newborns with respiratory distress syndrome (RDS. It is known that distending pressure generated by HFNC increases with increasing flow rate and decreasing infant size and varies according to the amount of leaks by nose and mouth. The effects of HFNC on lung mechanics, its clinical efficacy and safety are still insufficiently investigated. In conclusion, there is a growing evidence of the feasibility of HFNC as an alternative mode of NIV. However, further larger randomized trials are required, before being able to recommend HFNC in the treatment of moderate respiratory distress of preterm infants.

  4. Staphylococcal nasal carriage of health care workers.

    Science.gov (United States)

    Akhtar, Naeem

    2010-07-01

    To determine the frequency of staphylococcal nasal carriage of health care workers (HCWs) and antimicrobial susceptibility profile of the isolates for appropriate decolonization therapy. An observational study. The study was conducted at Holy Family Hospital, Rawalpindi, during the period from May 2007 to April 2008. Nasal swabs from anterior nares of HCWs were cultured and identified as Staphylococcus aureus, coagulasenegative staphylococci (CoNS), methicillin-resistant S. aureus (MRSA), methicillin-resistant CoNS (MRCoNS) by using standard methods. Antimicrobial susceptibility testing was performed on Muller Hinton Agar using disc diffusion method. Of the 468 HCWs, 213 (45.5%) participants were men and 255 (54.5%) were women. Eighty five (18.2%) were nasal carriers of S. aureus, 07 (1.5%) for MRSA, 343 (73.3%) for CoNS and 10 (2.1%) for MRCoNS. The highest carriage rate for S. aureus was in midwives (30%) followed by maintenance staff (28.6%), security guards (25%), technicians (23.5%), staff nurses (22.7%) and 90% of S. aureus and CoNS were susceptible to amikacin, gentamicin and fluoroquinolones tested. Fluoroquinolones, preferably oral levofloxacin in combination with topical gentamicin ointment, in places like Pakistan where mupirocin is not routinely available, can be used for decolonization of nasal staphylococcal carriage.

  5. Nasal prosthesis rehabilitation: a case report

    DEFF Research Database (Denmark)

    Jain, Sumeet; Maru, Kavita; Shukla, Jyotsana

    2011-01-01

    Facial defects resulting from neoplasm, congenital malformation or trauma can be restored with facial prosthesis using different materials and retention methods to achieve life-like look and function. A nasal prosthesis can re-establish esthetic form and anatomic contours for mid-facial defects...

  6. Fracture of nasal bones: an epidemiologic analysis

    Directory of Open Access Journals (Sweden)

    Fornazieri, Marco Aurélio

    2008-12-01

    Full Text Available Introduction: One of the most common diseases in the otorhinolaryngology emergency room is the nasal bones fracture. The peak of incidence is between 15 and 25 years of age. Generally men are more affected. Objective: To analyze the age, gender and the most frequent causes of nasal fractures evaluated in the otorhinolaryngology service of a tertiary hospital. Method: Retrospective study of records of the patients with nasal fracture diagnosis treated between July 1st, 2003 and July 1st, 2007. Results: 167 patients with nasal bones fracture were included in the study, including 134 men and 33 women. Violence was the most frequent cause, with 55 cases (32.9%, followed by fall from their own height, with 33 cases (19.7%, and motorcycle accident, 14 cases (8.4%. The most common age was between 21 and 39 years (46.1%. Conclusion: Male, age between 21 and 39 years and violence are the most common characteristics found in our service. Motorcycle accidents also play an important role in this affection.

  7. Nasal reconstruction with articulated irradiated rib cartilage

    Energy Technology Data Exchange (ETDEWEB)

    Murakami, C.S.; Cook, T.A.; Guida, R.A. (Univ. of Washington School of Medicine, Seattle (USA))

    1991-03-01

    Nasal structural reconstruction is a formidable task in cases where there is loss of support to both the nasal dorsum and tip. A multitude of surgical approaches and materials have been used for the correction of the saddle-nose deformity with varying degrees of success. Articulated irradiated rib cartilage inserted through an external rhinoplasty approach was used to reconstruct nasal deformities in 18 patients over a 6-year period. Simultaneous use of a midline forehead flap to reconstruct the overlying soft tissue was required in four cases. Follow-up ranged from 1 to 6 years (mean, 2.8 years). Results were rewarding in most cases with marked improvement in nasal support and airway. Revision and/or replacement secondary to trauma or warping of the graft was required in four cases. None of the patients exhibited infection, extrusion, or noticeable resorption. A description of the surgical technique, review of all the cases, and recommendation for continued use of this graft material are discussed.

  8. Sensory properties of selected terpenes. Thresholds for odor, nasal pungency, nasal localization, and eye irritation.

    Science.gov (United States)

    Cometto-Muñiz, J E; Cain, W S; Abraham, M H; Kumarsingh, R

    1998-11-30

    We tested four normosmics and four anosmics in detection thresholds for six terpenes commonly found indoors: cumene, p-cymene, delta-3-carene, linalool, 1,8-cineole and geraniol. Normosmics provided odor thresholds and anosmics provided nasal pungency thresholds. All subjects provided nasal localization (i.e., right/left nostril) and eye irritation thresholds. Each type of threshold was measured eight times per subject-stimulus combination. Stimuli were presented from squeeze bottles in a two-alternative forced-choice procedure via an ascending method of limits. Odor thresholds ranged between 0.1 and 1.0 parts per million (ppm, by volume). Nasal pungency thresholds lay about three orders of magnitude above odor thresholds. Nasal localization and eye irritation thresholds did not differ between normosmics and anosmics, and fell close to nasal pungency thresholds. Olfactory thresholds could be obtained for all stimuli in all repetitions using the criterion of five correct choices in a row. Trigeminal thresholds (i.e., pungency, localization and eye irritation) could be obtained on all repetitions only for some terpenes using that same criterion. Carene and cineol produced nasal pungency and eye irritation on all repetitions. None of the terpenes could be localized on all repetitions, but cineol was localized a higher percentage of instances than were the other stimuli. At the other extreme, geraniol failed to evoke any of the three trigeminal responses in most instances. Overall, the results indicate that the three trigeminal thresholds produce a uniform view of the potency of these terpenes, with nasal pungency and eye irritation being slightly more sensitive than nasal localization. Furthermore, application of a previously derived linear solvation energy relationship to the results reinforced the view that physicochemical properties can predict the chemesthetic impact of volatile organic compounds.

  9. Einfluss der Koordination von Spurenelementen in Silikatschmelzen auf Verteilungsprozesse

    OpenAIRE

    Sebastian Simon

    2016-01-01

    Das Wissen um die lokale Struktur von Seltenen Erden Elementen (SEE) in silikatischen und aluminosilikatischen Schmelzen ist von fundamentalem Interesse für die Geochemie der magmatischen Prozesse, speziell wenn es um ein umfassendes Verständnis der Verteilungsprozesse von SEE in magmatischen Systemen geht. Es ist allgemein akzeptiert, dass die SEE-Verteilungsprozesse von Temperatur, Druck, Sauerstofffugazität (im Fall von polyvalenten Kationen) und der Kristallchemie kontrolliert werden. All...

  10. Coblation nasal septal swell body reduction for treatment of nasal obstruction: a preliminary report.

    Science.gov (United States)

    Kim, So Jeong; Kim, Hee Tae; Park, Yun Hwi; Kim, Ju Yeon; Bae, Jung Ho

    2016-09-01

    In this paper, we present the results of coblation nasal septal swell body (NSB) reduction for the treatment of nasal obstruction in patients with abnormally thickened NSB. The study design was a retrospective clinical series conducted at a single tertiary medical center. Eight patients underwent coblation NSB reduction. Pre-operative and post-operative nasal functions were evaluated by acoustic rhinometry and subjective symptom scales. We also analyzed pre-operative CT scan images and nasal endoscopic findings. The mean maximal NSB width was 16.4 ± 2.2 mm on pre-operative coronal CT scan images. The mean visual analog scale score for nasal obstruction was decreased from preoperative 7.63 ± 0.99 points to 3.88 ± 0.92 points (postoperative 3 months), 4.16 ± 0.78 points (postoperative 6 months), and 4.63 ± 0.69 points (postoperative 1 year). Six out of the eight patients were satisfied with the clinical outcome at 1 year after the procedure. To the best of our knowledge, coblation NSB reduction has not yet been reported in the medical literature. Our results show that it can be an effective treatment modality for nasal valve narrowing in patients with abnormally thickened NSB.

  11. Possible risk and probability of causation of bone and liver cancer due to the occupational alpha-ray exposure of workers at the previous WISMUT Uranium Mining Company; Moegliches Risiko und Verursachungs-Wahrscheinlichkeit von Knochen-und Leberkrebs durch die berufliche Alphastrahlen-Exposition von Beschaeftigten der ehemaligen WISMUT-AG

    Energy Technology Data Exchange (ETDEWEB)

    Jacobi, W.; Roth, P. [GSF - Forschungszentrum fuer Umwelt und Gesundheit Neuherberg GmbH, Oberschleissheim (Germany). Inst. fuer Strahlenschutz; Nosske, D. [Bundesamt fuer Strahlenschutz, Neuherberg (Germany). Inst. fuer Strahlenhygiene

    1998-03-01

    For the calculation of the excess relative risk and the corresponding probability of causation the incidence data on bone and liver cancer from the DDR Cancer Registry are used as normal background rate. The application of these risk models to the exposure conditions of WISMUT workers takes into regard the inhalation of radon-222 and its progeny (including lead-210), the inhalation of U-containing or dust with large particle sizes and the external gamma radiation at the workplace. In addition, the possible risk contribution by drinking radioactive spring waters in these mines is discussed. In an annex the resulting risk values for bone and liver cancer per unit of exposure are tabulated as function of the time since exposure. As examples the resulting values of the excess absolute and relative risk and of the corresponding probability of causation as function of age at exposure and age at incidence are given for reference values of the annual radiation exposure of these miners. With respect to the time response the results indicate that a persistent relative risk model, like it has been derived by UNSCEAR for solid cancers on the basis of the LSS data from the atomic bomb survivors, seems to be not appropriate for bone and liver cancer induced by alpha radiation. - Finally it is recommended to apply the risk models for bone and liver cancer which are outlined in this report, for the decision-making on the compensation of WISMUT workers. (orig./GL) [Deutsch] Zur Berechnung des relativen Risikos und der daraus folgenden Verursachungs-Wahrscheinlichkeit werden als Normalwerte die Inzidenzdaten fuer Knochen- und Leberkrebs im DDR-Krebsregister herangezogen. Bei der Anwendung dieser Risikomodelle auf die Exposition von WISMUT-Beschaeftigten werden die Inhalation von Radon-222 und seinen Zerfallsprodukten (einschliesslich Blei-210), die Inhalation von grobdispersem Uran-haltigen Gesteinsstaub sowie die externe Gamma-Strahlung beruecksichtigt. Zusaetzlich wird auch der

  12. Nasal surgery in patients with systemic disorders

    Directory of Open Access Journals (Sweden)

    Sachse, Florian

    2010-01-01

    Full Text Available Multisystemic disorders represent a heterogenous group of diseases which can primarily manifest at the nose and paranasal sinuses as limited disease or secondarily as part of systemic involvement. Rhinologists therefore play an important role in the diagnostic but also therapeutic process. Although therapy of multisystemic disorders is primary systemic, additional rhinosurgery may become necessary. The spectrum of procedures consists of sinus surgery, surgery of the orbit and lacrimal duct, septorhinoplasty and closure of nasal septal perforation. Since the prevalence of most systemic diseases is very rare, recommendations are based on the analysis of single case reports and case series with a limited number of patients only. Although data is still limited, experiences published so far have shown that autologous cartilage or bone grafts can be used in nasal reconstruction of deformities caused by tuberculosis, leprosy, Wegener’s granulomatosis, sarcoidosis and relapsing polychondritis. Experiences gained from these diseases support the concept that well-established techniques of septorhinoplasty can be used in systemic diseases as well. However, a state of remission is an essential condition before considering any rhinosurgery in these patients. Even under these circumstances revision surgery has to be expected more frequently compared to the typical collective of patients undergoing septorhinoplasty. In addition, experiences gained from saddle nose reconstruction may in part be of value for the treatment of nasal septal perforations since implantation of cartilage grafts often represents an essential step in multilayer techniques of closure of nasal septal perforations. Aside from the treatment of orbital complications sinus surgery has been proven beneficial in reducing nasal symptoms and increasing quality of life in patients refractory to systemic treatment.

  13. Von Laue's theorem and its applications

    CERN Document Server

    Wang, Changbiao

    2012-01-01

    Von Laue's theorem is strictly proved in detail to clarify confusions in textbook and literature. This theorem is used to analyze the classical electron and the static electric field confined in a finite region of space.

  14. Arbeit von Frauen in Zeiten der Globalisierung

    NARCIS (Netherlands)

    D. Grunow

    2010-01-01

    Hohe Erwerbsquote, Dienstleistungsberufe und Minijobs: Die weibliche Erwerbstätigkeit hat sich in den letzten Jahrzehnten in Deutschland stark verändert. Wie hängen die Prozesse zusammen mit der Globalisierung von Wirtschaft und Arbeit?

  15. [A case of neurinoma of the nasal septum].

    Science.gov (United States)

    Sakamoto, Kikuo; Gondo, Kyujiro; Tomita, Kazuhide; Kasuya, Takao

    2003-05-01

    Neurinoma grows in the modulated nerve with Schwann cells, and is observed for all positions of the body. It is comparatively rare for neurinoma to grow in the nasal cavity and paranasal sinuses, however. We report a case of neurinoma of the nasal septum. A 24-year-old man seen for nasal obstruction was found in anterior rhinoscopy to have a tumor of the bilateral nasal cavity. Computed tomography (CT) showed a soft tissue density mass in the anterior part of the nasal cavity. Because we suspected neurinoma from biopsy, we resected the tumor by Denker's operation under general anesthesia. We found that it originated from the nasal septum. Histopathological findings of the tumor indicated an Antoni A type neurinoma. After surgery, cartilago costalis was transplanted the plastic surgery to correct the defect in the nasal septum. The post operative course was good and no signs of recurrence were seen. This is the 19th case found in the literature.

  16. Evaluation of the nasal shape after orthognathic surgery

    Directory of Open Access Journals (Sweden)

    Wagner Ranier Maciel Dantas

    2015-02-01

    Full Text Available Introduction: Patients with dentofacial deformities may benefit from orthognathic surgery in the maxilla. Maxillary osteotomy may include procedures in the bone, cartilaginous, and soft tissues of the nose, leading to shape alterations. Objective: To evaluate the anatomic alterations of the nasal region in patients undergoing a Le Fort I osteotomy for advancement or superior impaction. Methods: This is a clinical prospective study. Twenty-one patients were evaluated during the preand postoperative periods. The positioning of the nasal tip and the modification of the nasal base were evaluated. Results: The results showed that the nasal tip was superiorly positioned in 85% of the cases, advanced in 80%, rotated in 80%, and there was a wide nasal base in 95%, resulting in esthetic improvement. Conclusions: Surgeries of maxillary advancement and superior reposition tend to cause elevation and advancement of the nasal tip, as well as enlargement of the nasal base.

  17. Dialectal and gender differences in nasalance for a Mandarin population.

    Science.gov (United States)

    Kim, Ha-Kyung; Yu, Xiao-meng; Cao, Yan-jing; Liu, Xiao-ming; Huang, Zhao-Ming

    2016-01-01

    The purpose of this study was to determine whether there are dialectal and gender related differences in nasalance of main Mandarin vowels and three sentences in 400 Chinese normal adults. The mean nasalance score difference for dialect and gender was significant (p nasalance scores show that Chongqing > Beijing > Shanghai > Guangzhou for the nasal sentence, oro-nasal sentence, /a/, /i/ and /u/. In addition, the average nasalance scores of females were higher than those of males for all speech materials in all dialects. The clinical significance of this study can be helpful in making nasalance clinical decisions for Chinese people with cleft palate, hearing disorders and dysarthria with resonance disorders. It also shows the theoretical and socio-cultural features for linguists considering dialects and gender.

  18. Titanisierung von Implantatoberflächen

    Science.gov (United States)

    Zimmermann, Hanngörg; Heinlein, Markus; Guldner, Norbert W.

    Titan gilt seit Jahrzehnten als einer der wichtigsten Implantatwerkstoffe in der Medizin. Neben den guten mechanischen Eigenschaften (Leichtigkeit, hohe Festigkeit etc.), besitzen Titanimplantate vor allem eine hervorragende Körperverträglichkeit, so dass die Implantate optimal in den humanen Organismus integriert werden [1]. Ist jedoch aufgrund der Anforderungen an das Implantat eine hohe Flexibilität und/ oder Elastizität gefragt, so scheidet der Werkstoff Titan aufgrund seiner spröden und unflexiblen Materialeigenschaften aus. Die Folge ist der Einsatz von Implantatmaterialien, sowohl künstlichen als auch biologischen Ursprungs, welche nicht selten eine unzureichende Biokompatibilität aufweisen und somit zu Fremdköper- und immunologischen Reaktionen und Einkapselung des Implantates führen können. Die Erhöhung der Körperverträglichkeit, eine Adaption an das biologische Umfeld und eine hohe Biokompatibilität sind demzufolge die wichtigsten Eigenschaften bei der bedarfsgerechten Herstellung von Implantaten und Implantatoberflächen. Zur Gestaltung von innovativen, biokompatiblen Oberflächen stehen unterschiedliche technische Lösungsansätze zur Verfügung. Zum einen besteht die Möglichkeit, geeignete Oberflächeneigenschaften aus dem Grundmaterial selbst zu optimieren. Dies geschieht unter anderem durch Modifikation der Werkstoffoberflächen in Form von Texturierungen und Oberflächenrauhigkeiten. Zum anderen können die Oberflächeneigenschaften unabhängig von denen des Trägermaterials gestaltet werden. Durch Funktionalisierung der Oberflächen mit geeigneten Beschichtungen oder der Zugabe von Medikamenten (Drug Eluting) werden die Kunststoffimplantate dahingehend verändert, dass eine Steigerung der Körperakzeptanz erreicht wird. Die Titanbeschichtung von Implantatoberflächen kombiniert die positiven Materialeigenschaften von Titan und Polymer.

  19. Beschichtung von Kohlenstofffasern durch Chemische Gasphasenabscheidung (CVD)

    OpenAIRE

    Schmidt, Stephan

    2005-01-01

    Der Einsatz faserverstärkter Verbundwerkstoffe mit metallischer und keramischer Matrix bietet den Vorteil von Kombination und optimaler Ausnutzung verschiedenster Werkstoffeigenschaften. Die Verwendung einer durch Kohlenstofffasern verstärkten keramischen Matrix erlangte dabei in der kürzeren Vergangenheit vermehrtes Interesse. Grundlegend für den erfolgreichen Einsatz von Faserverbundwerkstoffen ist dabei ein optimiertes Faser-Matrix-Interface, also eine "optimale" Haftung der Fasern innerha...

  20. Studien zur didaktischen Nutzung von Concept Maps

    OpenAIRE

    Jüngst, Karl Ludwig

    1995-01-01

    In einer ersten Studie wurde geprüft, ob elaborierendes Durcharbeiten von Concept Maps lerneffektiver ist als elaborierendes Durcharbeiten von analogen Texten. Es wurden 13 Exemplare in unterschiedlichen Schulfächern im Sekundarschulwesen durchgeführt. Die Versuchs- Klassen arbeiten Concept Maps zu einem bestimmten Begriff durch, die Kontrollklassen analoge Texte. Die Behaltensleistung auf einfacherem Anforderungsniveau war in den Klassen mit Concept Maps besser als in den Klassen mit Texten....

  1. Hullud päevad von Krahlis

    Index Scriptorium Estoniae

    2006-01-01

    Von Krahli Teatris mängitakse neil päevi neli korda Peeter Jalaka lavastuses Tõnu Kõrvitsa kammeroopereid "Tuliaed" ja "Mu luiged, mu mõtted", mille aluseks on luuletaja Marie Heibergi saatus. Libreto autor on Maarja Kangro. Kammerooperid tulevad lavale Von Krahli Teatri ja Nargen Opera koostöös. Esitavad Kädy Plaas, Helen Lokuta, Nargen Opera koor ja Tallinna Kammerorkester, dirigent Tõnu Kaljuste

  2. 50th birthday of Christian von Ferber

    Directory of Open Access Journals (Sweden)

    2011-06-01

    Full Text Available On May 15, 2011 Christian von Ferber - member of the Editorial Board of "Condensed Matter Physics" and renowned expert in the fields of soft matter physics and complex systems - celebrated his 50th birthday. The Editorial board of CMP, colleagues and friends warmy congratulate Christian von Ferber and wish him and his family continuing good health and to enjoy many adventures and discoveries in his future scientific travels!

  3. Charakterisierung von Wechselwirkungsprozessen in sensitiven Schichten

    OpenAIRE

    Rathgeb, Frank

    1999-01-01

    Die vorliegende Arbeit soll verschiedene Strategien aufzeigen, um eine selektive Anreicherung gasförmiger Analytmoleküle in sensitiven Schichten zu erzielen. Im Mittelpunkt des Interesses lagen hierbei pH-responsive Polymere, mikroporöse Schichten und Cyclohexapeptide. Mit den pH-responsiven Polymeren konnte eine selektive und sensitive Detektion von Ammoniak mit Nachweisgrenzen von 150 ppb erreicht werden. Die Stabilität der sensitiven Schicht konnte im Vergleich zu farbstoffdotie...

  4. Hullud päevad von Krahlis

    Index Scriptorium Estoniae

    2006-01-01

    Von Krahli Teatris mängitakse neil päevi neli korda Peeter Jalaka lavastuses Tõnu Kõrvitsa kammeroopereid "Tuliaed" ja "Mu luiged, mu mõtted", mille aluseks on luuletaja Marie Heibergi saatus. Libreto autor on Maarja Kangro. Kammerooperid tulevad lavale Von Krahli Teatri ja Nargen Opera koostöös. Esitavad Kädy Plaas, Helen Lokuta, Nargen Opera koor ja Tallinna Kammerorkester, dirigent Tõnu Kaljuste

  5. MR-Imaging optimisation of the articular hip cartilage by using a T{sub 1}-weighted 3-dimensional gradient-echo sequence and the application of a hip joint traction; Magnetresonanztomographische Optimierung der Hueftknorpeldarstellung durch die Wahl einer T{sub 1}-Volumen-Gradienten-Echo-Sequenz und die Anwendung einer Hueftgelenkstraktion

    Energy Technology Data Exchange (ETDEWEB)

    Rosenberg, R. [Heidelberg Univ. (Germany). Orthopaedische Klinik und Poliklinik; Bernd, L. [Heidelberg Univ. (Germany). Orthopaedische Klinik und Poliklinik; Wrazidlo, W. [ATOS-Praxisklinik, Heidelberg (Germany). Radiologische Gemeinschaftspraxis Drs. Lederer, Schneider und Wrazidlo; Lederer, W. [ATOS-Praxisklinik, Heidelberg (Germany). Radiologische Gemeinschaftspraxis Drs. Lederer, Schneider und Wrazidlo; Schneider, S. [ATOS-Praxisklinik, Heidelberg (Germany). Radiologische Gemeinschaftspraxis Drs. Lederer, Schneider und Wrazidlo

    1995-10-01

    Images of three animal cadaver hips, 8 dissected patient femoral heads and 18 hip joints of human corpses, all either with arthrosis stage I-III or artificial cartilage defects, were compared with their corresponding anatomic sections. Additional histomorphologic examinations of the arthrotic cartilages were conducted, and MR-Imaging of 20 healthy and 21 arthrotic patient hips was performed using a specific traction method. Using a T{sub 1}-weighted 3-dimensional gradient-echo sequence and a traction of the hip joint, it was possible due to the low-signal imaging of the joint space to separate in vivo the high-signal femoral head cartilage from the high-signal acetabular cartilage. In horizontal position of the phase-encoding parameter, minimisation of the chemical-shift artifact, mainly in the ventro-lateral areas, was accomplished. MRI measurements of the articular cartilage widths showed significant correlations (p < 0.001) with the corresponding anatomic sections. At the same time the T{sub 1} 3-dimensional gradient-echo sequence of the lateral femoral head with r = 0.94 showed the lowest deviations of the measurements. It was possible with MR-Imaging to distinguish four cartilage qualities. (orig./MG) [Deutsch] Im experimentellen Teil der Studie wurden den MRT-Bildern von drei Kadavertierhueften, 8 resezierten Patientenhueftkoepfen und 18 Leichenhueftgelenken, an denen entweder artifizielle Knorpeldefekte gesetzt wurden oder die ein Koxarthrose-Stadium I-III aufwiesen, die korrespondierenden makroskopischen Kryomikrotomschnitte zugeordnet. Bei den Koxarthrosen erfolgten zusaetzliche histomorphologische Knorpeluntersuchungen. Im klinischen Teil der Studie wurden 20 gesunde und 21 arthrotische Probandenhueftgelenke mit einem speziellen Traktionsverfahren untersucht. Unter Anwendung einer T{sub 1}-Volumen-Gradienten-Echo-Sequenz und einer Traktion am zu untersuchenden Hueftgelenk konnte in vivo durch die signalarme Darstellung des Gelenkspaltes der

  6. Correlations of nasal responses to leukotriene D4 and histamine nasal provocation with quality of life in allergic rhinitis

    OpenAIRE

    Zhu, Zheng; Xie, Yanqing; Guan, Weijie; Gao, Yi; Xia, Shu; Shi, Xu; Zheng, Jinping

    2016-01-01

    Background The symptoms of allergic rhinitis (AR) greatly affect the quality of life (QoL) in the patients with AR. The correlations of nasal response to leukotriene D4 (LTD4) and histamine nasal provocation with health related QoL in AR are not clear. Objective To evaluate the correlations of nasal response to LTD4 and histamine nasal challenge with QoL in AR. Methods Patients randomly underwent LTD4 and histamine nasal challenge tests, completed the rhinoconjunctivitis quality of life quest...

  7. Nasalance measures in German-speaking cleft patients.

    Science.gov (United States)

    Swennen, Gwen R J; Grimaldi, Hannes; Upheber, Juliane; Kramer, Franz-Josef; Dempf, Rupert

    2004-01-01

    The purpose of this study was to evaluate nasalance measures in German-speaking patients with different types of repaired cleft lip and palate and to find out if significant nasalance gender differences exist in the different cleft groups. A total of 125 German-speaking cleft patients (74 male and 51 female) were included in this study: 18 patients with isolated unilateral cleft lip (UCL; mean age: 13.00 +/- 2.03 years), 66 patients with complete unilateral cleft lip and palate (UCLP; mean age: 14.80 +/- 3.45 years), 25 patients with isolated cleft palate (CP; mean age: 14.60 +/- 3.48 years), and 16 patients with complete bilateral cleft lip and palate (BCLP; mean age: 14.30 +/- 3.61 years). Nasalance data were collected and computed using the NasalView hardware/software system (Fa. Tiger Electronics, Seattle, WA). Speech stimuli according to a modified Heidelberg Rhinophonia Assessment Form (sustained vowels "a," "e," "i," "o," and "u"; oral and nasal sentences; and three oral-nasal reading passages) were used to obtain nasalance scores. Nasalance distance and ratio were also calculated for the oral and nasal sentences and for one of the oral-nasal reading passages. Unpaired t tests showed no significant gender nasalance differences in each cleft group. Analysis of variance showed no significant differences in mean nasalance distance and ratio. For the nasal sentence, a significant difference (P = 0.032) in mean nasalance scores was found between the UCL and UCLP groups.

  8. Development of CO{sub 2} sensors for residential living spaces. Final report; Entwicklung von CO{sub 2}-Sensoren fuer den privaten Lebensbereich. Abschlussbericht

    Energy Technology Data Exchange (ETDEWEB)

    Guertner, M.; Horn, M.; Neumann, N.; Pawelczak, D.; Schneider, F.; Traenkler, H.R.; Zhelondz, O.

    2004-07-01

    Indoors, people's performance capacity depends to a large degree on the quality of the room air. In private homes this is largely still a question of manual ventilation. According to the German Energy Saving Ordinance (EnEV), which took effect in February 2003 and which encourages the design of air-tight building envelopes, the best way to achieve an air exchange rate conducive to well-being and hygiene is to have a decentralised heating and ventilation control system which adjusts air conditions as required. These systems use CO{sub 2} concentration as a criterion for ventilation requirement and air quality, thus creating a demand for inexpensive, durable CO{sub 2} sensors. The present paper reports on a research project for the conceptualisation and development of a CO{sub 2} sensor system for use in office and residential spaces. [German] Die Leistungsfaehigkeit von Menschen haengt in hohem Masse von der Raumluftqualitaet ab, die bisher in Wohnungen vorwiegend durch manuelle Lueftung erreicht wird. Der fuer das Wohlbefinden und die Hygiene erforderliche Luftwechsel sollte aufgrund der seit Februar 2003 in Kraft getretenen Energieeinsparungsverordnung (EnEV) und den darin geforderten luftdichten Gebaeudehuellen zukuenftig sinnvollerweise durch eine bedarfsgerechte, dezentrale Heizungs- und Lueftungssteuerung sichergestellt werden. Mit der Heranziehung der CO{sub 2}-Konzentration als Kriterium fuer den Lueftungsbedarf und die Luftqualitaet werden somit kostenguenstige und langzeitstabile CO{sub 2}-Sensoren unabdingbar. Im Rahmen des Forschungsprojektes wurde das in der Arbeit behandelte CO{sub 2}-Sensorsystem fuer die Anwendung in Buero- und Wohnbereichen konzipiert und entwickelt. (orig.)

  9. Contested Inclusions: Pitfalls of NGO Peace-Building Activities in Liberia Umstrittene Inklusion: Fallstricke bei peace-building-Aktivitäten von NRO in Liberia

    Directory of Open Access Journals (Sweden)

    Veronika Fuest

    2010-01-01

    Full Text Available In post-war situations, non-governmental organizations (NGOs feature highly in peace-building processes in their (perceived capacities as both representatives of civil society and as grassroots agents to be employed in the reconstruction and transformation of society. As elsewhere, in Liberia, peace-building approaches include, first, international blueprints of representation that intend to empower groups generally perceived to be socially subordinate and, second, supporting traditional institutions considered social capital in reconciliation. Using the example of Liberia, this paper explores how in local conflict arenas, NGO workshops – the most popular mode of participatory intervention – are interpreted and appropriated by local actors; it highlights some fallacies and unintended consequences of inclusive procedures in practice and questions the support furnished to heads of gendered secret societies. Nichtregierungsorganisationen (NRO wird in Nachkriegsphasen hohe Kompetenz in Bezug auf peace-building-Prozesse zugesprochen, denn sie repräsentieren die civil society und stellen gleichzeitig Akteure, die an der Basis zum Wiederaufbau und zur gesellschaftlichen Transformation beitragen können. Auch in Liberia schließen peace-building-Konzepte an erster Stelle international erarbeitete Zielvorgaben zur Repräsentanz ein und sehen erstens eine Beteiligung von Gruppen mit niedrigem sozialen Status vor und zweitens die Unterstützung traditioneller Institutionen, die als soziales Kapital im Aussöhnungsprozess angesehen werden. Die Autorin untersucht am Beispiel Liberia, inwieweit NRO-workshops – die beliebteste Form der partizipativen Intervention – in Konfliktzonen von lokalen Akteuren interpretiert und für eigene Ziele genutzt werden; sie verweist auf irrtümliche Annahmen und unbeabsichtigte Konsequenzen der praktischen Anwendung inklusiver Verfahren und stellt die Unterstützung in Frage, die Oberhäuptern geschlechtsspezifischer

  10. Nasal Carriage of 200 Patients with Nasal Bone Fracture in Korea

    Directory of Open Access Journals (Sweden)

    Jun Wook Lee

    2013-09-01

    Full Text Available Background Pathogens in the nasal cavity during nasal surgery could lead to a systemicinfectious condition, such as bacteremia, nosocomial infection, or toxic shock syndrome.However, there is no research about the prevalence of nasal carriage in patients with nasalbone fracture.Methods This was a prospective, double-blind, randomized study about the rate of nasalcarriage in 200 patients with nasal bone fracture in Korea. Nasal secretions were taken fromboth the middle nasal meatus and colonized. All analyses were carried out using SPSS software.Results Pathogens were identified in 178 of the 200 cases. Coagulase-negative staphylococci(CNS were the most cultured bacteria in 127 (66.84% of the 190 total patients after excluding10 cases of contaminated samples, and methicillin-resistant coagulase-negative staphylococci(MRCNS were found in 48 (25.26%. Staphylococcus aureus was the second mostidentified pathogen, found in 36 (18.95%, followed by 7 cases (3.68% of methicillin-resistantStaphylococcus aureus (MRSA. The prevalence rate of MRSA in the females was higher thanthat in the males (RR=4.70; 95% CI, 1.09-20.18, but other demographic factors had no effecton the prevalence rate of MRSA and MRCNS.Conclusions The prevalence rate of these pathogens in patients with nasal bone fracture inKorea was similar to other reports. However, few studies have addressed the prevalence rateof CNS and MRCNS in accordance with risk factors or the change in prevalence according tospecific prophylaxis against infectious complications. Additional research is needed on thepotential connections between clinical factors and microbiological data.

  11. Automation of ultrasonic testing, instrumentation and rules for application and evaluation. Proceedings; Automatisierung der Ultraschallpruefung, Geraetetechnik und Regeln zur Anwendung und Auswertung. Vortraege des Seminars

    Energy Technology Data Exchange (ETDEWEB)

    Wuestenberg, H. [comp.

    1997-12-31

    The proceedings volume contains 18 lectures of the seminar addressing the following (selected) aspects: Requirements to be met by PC cards for US testing applications, defined by producers and appliers; digital technology and its impact on multichannel US testing instruments; the ALOK and array systems combined into one very efficient testing system (SAPHIR); a testing system combining US radiation source arrays and the pulsed eddy current method by means of highly integrated microelectronics (ASICs); regulatory standards and specifications for automated US testing; requirements for automated US testing in compliance with nuclear engineering codes; state of the art in standardisation for definition of required properties of US testing systems; critical review of the proposed standard relating to the TOFD method; automated evaluation shown with the example of US testing of pipelines. (orig./CB) [Deutsch] Dieser Band enthaelt 18 Vortraege mit folgenden Themen (Auswahl): Anforderungen an Ultraschall-PC-Karten aus der Sicht von Hersteller und Betreiber; Einfluss der Digitaltechnik auf Mehrkanal-Ultraschall-Pruefanlagen; Vereinigung der ALOK- und der Gruppenstrahler-Technik in einem leistungsfaehigen Pruefsystem (SAPHIR); Ein kombiniertes Pruefsystem fuer die Ultraschall-Gruppenstrahler- und Impuls-Wirbelstrom-Technik auf der Basis von hochintegrierter Mikroelektronik (ASICs); Regelwerke und Spezifikationen fuer die automatisierte Ultraschallpruefung; Anforderungen der kerntechnischen Regelwerke an die automatisierte Ultraschallpruefung; Stand der Normung bei der Charakterisierung der Eigenschaften von Ultraschall-Pruefsystemen; Kritische Bewertung des Normungsvorschlages zur Beugungslaufzeittechnik (TOFD); und Automatisierte Auswertung am Beispiel der Ultraschallpruefung von Fernrohrleitungen. (orig.)

  12. Automation of ultrasonic testing, instrumentation and rules for application and evaluation. Proceedings; Automatisierung der Ultraschallpruefung, Geraetetechnik und Regeln zur Anwendung und Auswertung. Vortraege des Seminars

    Energy Technology Data Exchange (ETDEWEB)

    Wuestenberg, H. [comp.

    1997-12-31

    The proceedings volume contains 18 lectures of the seminar addressing the following (selected) aspects: Requirements to be met by PC cards for US testing applications, defined by producers and appliers; digital technology and its impact on multichannel US testing instruments; the ALOK and array systems combined into one very efficient testing system (SAPHIR); a testing system combining US radiation source arrays and the pulsed eddy current method by means of highly integrated microelectronics (ASICs); regulatory standards and specifications for automated US testing; requirements for automated US testing in compliance with nuclear engineering codes; state of the art in standardisation for definition of required properties of US testing systems; critical review of the proposed standard relating to the TOFD method; automated evaluation shown with the example of US testing of pipelines. (orig./CB) [Deutsch] Dieser Band enthaelt 18 Vortraege mit folgenden Themen (Auswahl): Anforderungen an Ultraschall-PC-Karten aus der Sicht von Hersteller und Betreiber; Einfluss der Digitaltechnik auf Mehrkanal-Ultraschall-Pruefanlagen; Vereinigung der ALOK- und der Gruppenstrahler-Technik in einem leistungsfaehigen Pruefsystem (SAPHIR); Ein kombiniertes Pruefsystem fuer die Ultraschall-Gruppenstrahler- und Impuls-Wirbelstrom-Technik auf der Basis von hochintegrierter Mikroelektronik (ASICs); Regelwerke und Spezifikationen fuer die automatisierte Ultraschallpruefung; Anforderungen der kerntechnischen Regelwerke an die automatisierte Ultraschallpruefung; Stand der Normung bei der Charakterisierung der Eigenschaften von Ultraschall-Pruefsystemen; Kritische Bewertung des Normungsvorschlages zur Beugungslaufzeittechnik (TOFD); und Automatisierte Auswertung am Beispiel der Ultraschallpruefung von Fernrohrleitungen. (orig.)

  13. Augmentation Rhinoplasty in Cleft Lip Nasal Deformity: Preliminary Patients’ Perspective

    Directory of Open Access Journals (Sweden)

    William H. C. Tiong

    2014-01-01

    Full Text Available The correction of cleft lip nasal deformity is challenging and there have been numerous methods described in the literature with little demonstrated technical superiority of one over another. The common clinical issues associated with cleft lip nasal deformity are its lack of symmetry, alar collapse on the affected side, obtuse nasal labial angle, short nasal length, loss of tip definition, and altered columella show among others. We carried out augmentation of cleft lip rhinoplasties with rib graft in 16 patients over the one-year study period. Each of these patients was reviewed and given questionnaire before and after surgery to evaluate their response on the outcome to the approach. Preoperatively, nasal asymmetry is the main complaint (14/16, 87.5% among our series of patients. Postoperatively, 12 (75% patients out of the 16 reported significant improvement in their nasal symmetry with the other four marginal. All patients reported excellent nasal projection postoperatively with good nasal tip definition. Our series of patients reported overall good satisfaction outcome and will recommend this procedure to other patients with cleft lip nasal deformity. In conclusion, augmentation of cleft lip rhinoplasty can be employed to achieve perceivable and satisfactory outcome in patients with cleft lip nasal deformity.

  14. Fundus imaging with a nasal endoscope

    Directory of Open Access Journals (Sweden)

    P Mahesh Shanmugam

    2015-01-01

    Full Text Available Wide field fundus imaging is needed to diagnose, treat, and follow-up patients with retinal pathology. This is more applicable for pediatric patients as repeated evaluation is a challenge. The presently available imaging machines though provide high definition images, but carry the obvious disadvantages of either being costly or bulky or sometimes both, which limits its usage only to large centers. We hereby report a technique of fundus imaging using a nasal endoscope coupled with viscoelastic. A regular nasal endoscope with viscoelastic coupling was placed on the cornea to image the fundus of infants under general anesthesia. Wide angle fundus images of various fundus pathologies in infants could be obtained easily with readily available instruments and without the much financial investment for the institutes.

  15. Saline Nasal Irrigation for Upper Respiratory Conditions

    Science.gov (United States)

    2009-01-01

    Acute and chronic upper respiratory conditions are common and expensive disorders with enormous impact on patient quality of life and society at large. Saline nasal irrigation (SNI), a therapy with roots in Ayurvedic medicine that bathes the nasal mucosa with in spray or liquid saline, has been used as adjunctive care for upper respiratory conditions. In liquid form, SNI has been found to be effective adjunctive care by the Cochrane Collaboration for symptoms associated with chronic rhinosinusitis. Less conclusive clinical trial evidence supports its use in spray and liquid forms as adjunctive treatment for mild-to-moderate allergic rhinitis and acute upper respiratory infections. Consensus or expert opinion recommendations exist for SNI as a treatment for a variety of other conditions including rhinitis of pregnancy. SNI appears safe; side effects are minimal and transient. It can be recommended by clinicians to interested patients with a range of upper respiratory conditions in the context of patient education and printed instructional handouts. PMID:19904896

  16. SEPTOPLASTY WITH AND WITHOUT NASAL PACKING: A COMPARATIVE STUDY

    Directory of Open Access Journals (Sweden)

    Mitta

    2016-05-01

    Full Text Available Septoplasty is one of the most commonly performed surgeries in rhinology to relieve nasal obstruction of patients with distortion in the midline cartilage or septum of the nose to relieve nasal obstruction of patient and findings consistent with nasal endoscopy. The anterior nasal packing routinely done following septoplasty is usually conventional and not evidence based. The purpose of nasal packing is to obtain haemostasis, enhance opposition of septal flaps, avoid septal haematoma formation, close the dead space, avoid synechiae formation, provide support to septal cartilage and prevent its displacement. OBJECTIVE This study intends to evaluate the effects of nasal packing on surgical success and related complications in septoplasty. MATERIALS AND METHODS The present clinical prospective and randomised study was carried out on patients attending Otorhinolaryngology Department of Santhiram Medical College & General Hospital between March 2012 and March 2015. Patients undergoing septoplasty were randomised either to receive anterior nasal packing or to not receive nasal packing postoperatively. RESULTS Levels of pain experienced by patients with nasal packing postoperatively during the initial 24 hours postoperatively and during the removal of the pack were significantly more. Post-operative headache, epiphora, swallowing discomfort and sleep disturbance were more in patients with nasal packing and statistically (p.05. Septal haematoma, adhesions and local infections in both groups were statistically insignificant (p>.05. CONCLUSION Septoplasty enhances the standard of living of patients with septal deviation and nasal obstruction. Our study results suggest that nasal packing after septoplasty is not obligatory. Nasal packing causes considerably more pain and complications, and it should be reserved only for those who have bleeding predisposition.

  17. Assessment of the effect of deviated nasal septum on the structure of nasal cavity.

    Science.gov (United States)

    Wang, Junguo; Dou, Xin; Liu, Dingding; Song, Panpan; Qian, Xiaoyun; Wang, Shoulin; Gao, Xia

    2016-06-01

    The present study was aimed to investigate the effects of DNS on the structure of nasal cavity. The paranasal sinus coronal view CT of 108 patients with DNS and 129 hospitalized patients without DNS was retrospectively analyzed. The transverse diameter of nasal cavity (a), transverse diameter of nasal cavity and paranasal sinus (b), angle between maxillary and palatal bone, interalveolar distance, and maxillary rotation distance were measured. The ratio of a/b in experimental group was 0.367 ± 0.006 which was significantly (P = 0.0023) less than that in control group (0.391 ± 0.005). For the angle between maxillary and palatal bone, there was no significant difference found between DNS and control group for both right and left sides. The interalveolar distance was 40.75 mm in experimental group, and 38.8 mm in control (P = 0.0002). For the maxillary rotation distance, findings were considered as significant (P DNS affects the development of nasal cavity and paranasal sinus, as well as increases the interalveolar distance and maxillary rotation distance. These influences may be caused by the alteration of airflow inside the nasal cavities.

  18. Practical application of the microbial activity analysis on the monitoring of the process biological stability of biogas plants; Praktische Anwendung der mikrobiellen Aktivitaetsanalyse zur Ueberwachung der prozessbiologischen Stabilitaet von Biogasanlagen

    Energy Technology Data Exchange (ETDEWEB)

    Neumann, Lukas; Tietjen, Carsten [MT-Energie GmbH, Zeven (Germany). Forschung und Entwicklung; Rilling, Norbert [MT-Energie GmbH und Co. KG, Rockstedt (Germany)

    2013-10-01

    As extension for the classical fluorescence microscopic analysis of the microbial population in a biogas fermenter the cell counts and frequency of the different methanogenic organisms was used to generate the plant specific stability indicator called MT-Factor. This factor describes the optimal composition of the microbial population for the current process conditions and could be used for the biological process consulting. A study of the MT-Energie laboratory showed that the combination of the microbial cell counts determination and the plant specific stability factor shifts during a process instability or failure of a biogas fermenter. This analysis of the methane-forming microorganisms as well as their cell count and importance for the entire anaerobic biology of the biogas plant can be used for clearly visualizing and tracking the vitality of the digestion process. The evaluation of the microbial activity of different liquid manure samples could show the influence of inhibitors like disinfectant or cleaning agents directly without time consuming cultivation tests. By determining the MT-Factor and analyzing the activity of the methane formers, an impending influence of inhibitors can be detected in liquid manure before the manure enters the digester. This way, a negative influence on the gas yield can be avoided. (orig.)

  19. GIS supported survey of potentials of wind power. Application of the Weibull distribution for site identification in the community Schesslitz, Bavaria; GIS-gestuetzte Erhebung von Windkraftpotenzialen. Anwendung der Weibull-Verteilung zur Standortfindung in der Gemeinde Schesslitz, Bayern

    Energy Technology Data Exchange (ETDEWEB)

    Nuehlen, Jochen

    2010-07-15

    By means of the legislative framework, the use of wind power is anchored in the economic and ecological development of Germany. The development of the utilization of wind energy on inland locations requires a detailed survey of potential with results as realistic as possible. As part of the Climate Alliance Bamberg (Federal Republic of Germany) a potential analysis of all renewable energies is to be created. Under this aspect, the author of the contribution under consideration reports on a GIS-based analysis of the wind power. An exemplary demonstration of the results is done at the community Schesslitz (Bavaria, Federal Republic of Germany). Two different methods for the analysis of the potential of wind energy are presented.

  20. Non-Markovian dynamics, decoherence and entanglement in dissipative quantum systems with applications to quantum information theory of continuous variable systems; Nicht-Markovsche Dynamik, Dekohaerenz und Verschraenkung in dissipativen Quantensystemen mit Anwendung in der Quanteninformationstheorie von Systemen kontinuierlicher Variablen

    Energy Technology Data Exchange (ETDEWEB)

    Hoerhammer, C.

    2007-11-26

    In this thesis, non-Markovian dynamics, decoherence and entanglement in dissipative quantum systems are studied. In particular, applications to quantum information theory of continuous variable systems are considered. The non-Markovian dynamics are described by the Hu-Paz-Zhang master equation of quantum Brownian motion. In this context the focus is on non-Markovian effects on decoherence and separability time scales of various single- mode and two-mode continuous variable states. It is verified that moderate non-Markovian influences slow down the decay of interference fringes and quantum correlations, while strong non-Markovian effects resulting from an out-of-resonance bath can even accelerate the loss of coherence, compared to predictions of Markovian approximations. Qualitatively different scenarios including exponential, Gaussian or algebraic decay of the decoherence function are analyzed. It is shown that partial recurrence of coherence can occur in case of non-Lindblad-type dynamics. The time evolution of quantum correlations of entangled two-mode continuous variable states is examined in single-reservoir and two-reservoir models, representing noisy correlated or uncorrelated non-Markovian quantum channels. For this purpose the model of quantum Brownian motion is extended. Various separability criteria for Gaussian and non-Gaussian continuous variable systems are applied. In both types of reservoir models moderate non-Markovian effects prolong the separability time scales. However, in these models the properties of the stationary state may differ. In the two-reservoir model the initial entanglement is completely lost and both modes are finally uncorrelated. In a common reservoir both modes interact indirectly via the coupling to the same bath variables. Therefore, new quantum correlations may emerge between the two modes. Below a critical bath temperature entanglement is preserved even in the steady state. A separability criterion is derived, which depends on the bath temperature and the response function of the open quantum system. Thus, the extended quantum Brownian motion model of a two-mode continuous variable system in a common reservoir provides an example of quantum noise-induced entanglement. (orig.)

  1. Radiation dose evaluation during X-ray examinations in human medicine, dentistry, veterinary medicine and border controls using ionizing radiation; Dosisermittlung bei der Anwendung von Roentgenstrahlung in der medizinischen Heilkunde, zahnmedizinischen Heilkunde, Tierheilkunde und bei Grenzkontrollen mit ionisierender Strahlung. Abschlussbericht

    Energy Technology Data Exchange (ETDEWEB)

    Ankerhold, U; Hupe, O. [Physikalisch-Technische Bundesanstalt, Braunschweig (Germany)

    2012-02-15

    The report on radiation dose evaluation during X-ray examinations includes the following chapters: (1) Scope of the project. (2) Measuring instruments. (3) Part I: Radiation dose evaluation during X-ray examinations in human medicine, dentistry, veterinary medicine. (4) Radiation dose evaluation during X-ray examinations during border controls using ionizing radiation. (5) Summary of results.

  2. 3D characterization of thermal fatigue damage in monofilament reinforced copper for heat sink applications in fusion reactor systems; 3D-Charakterisierung von thermischer Ermuedungsschaedigung in Monofilament verstaerktem Kupfer zur Anwendung als Waermeleiter in Kernfusionsreaktorsystemen

    Energy Technology Data Exchange (ETDEWEB)

    Schoebel, Michael; Degischer, H. Peter [Vienna Univ. of Technology (Austria). Inst. of Materials Science and Technology; Brendel, Annegret [Max-Planck-Institut fuer Plasmaphysik, Garching (Germany); Harrer, Bernhard [Upper Austria Univ. of Applied Sciences, Wels (Austria); Di Michiel, Marco [European Synchrotron Radiation Facility (ESRF), 38 - Grenoble (France)

    2012-07-01

    Monofilament reinforced metals (MFRM) are developed as high temperature heat sink materials for fusion reactor applications. These composites combine the high thermal conductivity (TC) of a Cu matrix with low thermal expansion (CTE) of SiC or W filaments. The CTE mismatch between matrix and reinforcement lead to high micro stresses under operation conditions. Stress induced thermal fatigue damage such as interface delamination and fiber/matrix damage degrades the thermal properties of these composites. Different interface designs are developed for SiC as well as W filaments to improve bonding strength and increase the long term stability. Conventional as well as synchrotron tomography was applied on different MFRMs to characterize thermal fatigue damage and its propagation before, during and after thermal cycling. (orig.)

  3. Investigations of the oxidation-induced service life of chromium steels for high temperature fuel cell application (SOFC); Untersuchungen zur oxidationsbedingten Lebensdauer von Chromstaehlen fuer die Anwendung in der Hochtemperaturbrennstoffzelle (SOFC)

    Energy Technology Data Exchange (ETDEWEB)

    Ertl, S.T.

    2006-08-17

    The increasing energy consumption of future automobiles should be covered by a solid oxide fuel cell (SOFC) used as an additional energy supply (auxiliary power unit). The application of a SOFC with about 5 kW power in cars requires small size, low weight and an economic fabrication. To achieve this goal the interconnector and the metallic anode substrate (depending on an alternative concept of construction) should be manufactured out of thin Crofer22APU, a high chromium ferritic steel. The scale formation mechanisms on Crofer22APU sheets, wires and powder metallurgical produced foils of different thicknesses were investigated in several atmospheres of water vapour/hydrogen at 800 and 900 C, simulating the anode conditions. For scale characterization a number of conventional analysis techniques such as optical metallography, scanning electron microscopy and X-ray diffraction were used in combination with deflection testing in monofacial oxidation and two-stage oxidation studies using {sup 18}O and H{sub 2} {sup 18}O tracer. With these results a theoretical model for the determination of lifetime was developed for Crofer22APU components in simulated anode gas. It was found that the lifetime at a given temperature depends not only on the surface-to-volume ratio, but also on the geometry of the component (e.g. sheet or wire). The critical Cr content required for breakaway oxidation depends on microcrack formation in the surface oxide scale, which occurs on ridges of a sheet during thermal cycling. The development of a metallic interconnector and a metallic anode substrate requires measures to avoid interdiffusion between the alloy and the bordering nickel-YSZ (yttrium stabilized zirconia) cermet of the anode, or depending on the conception of the stack, the bordering nickel-YSZ cermet of the anode functional layer. Therefore the suitability of preoxidation layers after different preoxidation conditions was tested. It was found that the inhibition of the interdiffusion depends not only on the preoxidation conditions, but also on the conditions under which the nickel layer was applied. (orig.)

  4. Application of extracellular gadolinium-based MRI contrast agents and the risk of nephrogenic systemic fibrosis; Anwendung von extrazellulaeren gadoliniumhaltigen MR-Kontrastmitteln und Risiko der Nephrogenen Systemischen Fibrose

    Energy Technology Data Exchange (ETDEWEB)

    Heverhagen, J.T. [Univ. Hospital Bern (Switzerland). Inst. of Diagnostic, Interventional and Pediatric Radiology, Inselspital; Krombach, G.A. [Justus Liebig Univ. Hopsital Giessen (Germany). Diagnostic and Interventional Radiology; Gizewski, E. [Medical Univ. Innsbruck (Austria). Dept. of Neuroradiology

    2014-07-15

    Nephrogenic systemic fibrosis (NSF) is a serious, sometimes fatal disease. Findings in recent years have shown that a causal association between gadolinium containing contrast media and NSF is most likely. Therefore, the regulatory authorities have issued guidelines on the use of gadolinium-containing contrast media which have reduced the number of new cases of NSF to almost zero. However, it is for precisely this reason that the greatest care must still be taken to ensure that these guidelines are complied with. The most important factors are renal function, the quantity of gadolinium administered and coexisting diseases such as inflammation. All of these factors crucially influence the quantity of gadolinium released from the chelat in the body. This free gadolinium is thought to be the trigger for NSF. Other important factors are the stability of the gadolinium complex and furthermore the route of its elimination from the body. Partial elimination via the liver might be an additional protective mechanism. In conclusion, despite the NSF risk, contrast-enhanced MRI is a safe diagnostic procedure which can be used reliably and safely even in patients with severe renal failure, and does not necessarily have to be replaced by other methods.

  5. Scaling up manufacturing of ZnO thin layers for application in flexible dye-sensitized solar cells; Aufskalierung der Herstellung von ZnO-Duennschichten fuer die Anwendung in flexiblen farbstoffsensibilisierten Solarzellen

    Energy Technology Data Exchange (ETDEWEB)

    Bittner, Florian

    2012-10-19

    Flexible solar cells possess good future prospects for versatile mobile applications and can provide an important environmental benefit. One of the technologies permitting flexible solar cells is that of dye-sensitized solar cells. Among other advantages the fabrication of these organic-inorganic hybrid solar cells promises to be inexpensive in comparison to other technologies. Nanoparticular TiO{sub 2} is used predominantly as the semiconducting photoanode material; however its preparation route contains a tempering step at about 450 C, which impedes the use of flexible plastic substrates - at least with the method established for dye-sensitized solar cells. An alternative to TiO{sub 2} is ZnO, which can be fabricated for example in an electrochemical process at temperatures of only 70 C in the form of porous quasicrystalline layers. To create porosity the dye eosin Y is used as structure-directing agent. In the context of this study layers prepared by this method were compared to ZnO layers prepared by screen printing. This was performed on glass based substrates. Better conversion efficiency has been determined for dye-sensitized solar cells based on electrochemical deposited layers, while other results indicated advantages for the screen printed layers. As the morphologies of the available screen printed layers proved to be unfavourable and poorly comparable, a concluding statement on the suitability of the different types of layers was eventually not possible. Furthermore a technical simple and inexpensive method for the platinum coating of plastic substrates, which are used as counter electrodes, was tried to be determined. However, layers prepared by technically relatively complex sputtering exhibited by far better properties than layers prepared by electrochemical deposition or by chemical reduction of platinum salts. Thus, the targeted objective has not been reached. The central scope of this study was the development of an electrochemical deposition setup to demonstrate the suitability for scale-up of the fabrication method of ZnO/eosin Y hybrid layers. This miniplant setup was characterised in detail and appropriate deposition parameters have been determined. Porous ZnO layers have been prepared successfully on FTO glass substrates on an area of 38.88 cm{sup 2} and on ITO-PET plastic substrates on an area of 34.56 cm{sup 2}. The suitability of the fabricated layers for the assembly of flexible dye-sensitized solar cells has been demonstrated by means of several operative modules. While these modules achieved decent conversion efficiencies of up to 2.58 % under low light intensities, strongly decreasing conversion efficiencies were observed with increasing light intensities. Too high series resistances have been identified as the cause. (orig.)

  6. The use of web based monitoring and analysis-based platforms for the monitoring of slopes in opencast mines and quarries; Die Anwendung Web-basierter Monitoring- und Analyse-Plattformen fuer die Ueberwachung von Boeschungen in Steinbruechen und Tagebauen

    Energy Technology Data Exchange (ETDEWEB)

    Graf, Thomas; Fyfe, Timothy D. [Fugro Consult GmbH, Berlin (Germany)

    2010-07-15

    These days, ensuring the technical and operational safety requirements, is one of the core activities in the operation of quarries and open pit mines. Especially, the geotechnical stability of slopes during open pit operations contains a considerable risk potential. (orig.)

  7. Quasistatic field simulations based on finite elements and spectral methods applied to superconducting magnets; Quasistatische Feldsimulationen auf der Basis von Finiten Elementen und Spektralmethoden in der Anwendung auf supraleitende Magnete

    Energy Technology Data Exchange (ETDEWEB)

    Koch, Stephan

    2009-03-30

    This thesis is concerned with the numerical simulation of electromagnetic fields in the quasi-static approximation which is applicable in many practical cases. Main emphasis is put on higher-order finite element methods. Quasi-static applications can be found, e.g., in accelerator physics in terms of the design of magnets required for beam guidance, in power engineering as well as in high-voltage engineering. Especially during the first design and optimization phase of respective devices, numerical models offer a cheap alternative to the often costly assembly of prototypes. However, large differences in the magnitude of the material parameters and the geometric dimensions as well as in the time-scales of the electromagnetic phenomena involved lead to an unacceptably long simulation time or to an inadequately large memory requirement. Under certain circumstances, the simulation itself and, in turn, the desired design improvement becomes even impossible. In the context of this thesis, two strategies aiming at the extension of the range of application for numerical simulations based on the finite element method are pursued. The first strategy consists in parallelizing existing methods such that the computation can be distributed over several computers or cores of a processor. As a consequence, it becomes feasible to simulate a larger range of devices featuring more degrees of freedom in the numerical model than before. This is illustrated for the calculation of the electromagnetic fields, in particular of the eddy-current losses, inside a superconducting dipole magnet developed at the GSI Helmholtzzentrum fuer Schwerionenforschung as a part of the FAIR project. As the second strategy to improve the efficiency of numerical simulations, a hybrid discretization scheme exploiting certain geometrical symmetries is established. Using this method, a significant reduction of the numerical effort in terms of required degrees of freedom for a given accuracy is achieved. The problem-tailored discretization approach is based on a geometrical modeling of reduced spatial dimension inside respective domains of symmetry. For the approximation of the electromagnetic fields, orthogonal polynomials along the direction of symmetry are combined with finite element shape functions at the remaining cross-section. This leads to an efficient method providing a high accuracy. The domains of symmetry are embedded into the surrounding region by means of a strong coupling at the discrete level in terms of a domain decomposition approach. Using this strategy, for certain examples a level of accuracy corresponding to numerical models featuring several millions of degrees of freedom in classical finite element methods can be achieved with only one hundred thousand unknowns. This is demonstrated for different examples, e.g., a cylindrical power transformer and the already mentioned accelerator magnet. (orig.)

  8. Laser ablation of SiO{sub 2} passivating layers with application to the RISE-EWT solar cell; Laserstrahlablation von SiO{sub 2}-Passivierschichten mit Anwendung auf die RISE-EWT-Solarzelle

    Energy Technology Data Exchange (ETDEWEB)

    Hermann, Sonja

    2011-07-01

    The generation of electric current by mea ns of photovoltaic is an alternative to the so far intensively used fossil energy sources and nuclear energy generation. Thereby, the wafer based silicon (Si) technology holds the main part of the worldwide installed photovoltaic power. Particularly the standard screen-printed solar cell, which achieves on monocrystalline silicon wafer energy conversion efficiencies in the range of 17%. is industrially established. However, highly efficient back cont acted solar cells, as the RISE-EWT solar cell, allegorize an attractive alternative. In this work a full area rear side SiO{sub 2} passivation is implemented into the concept of the RISE-EWT solar cell and thus the efficiency potential of this cell is improved. By optimizing process parameters for the fabrication of this rear side passivation by means of thermal oxidation conversion efficiencies > 21% are achieved. Furthermore, in order to make this advanced RISE-EWT solar cell concept industrially feasible, a laser ablation process for the fabrication of local emitter and base contact openings into the SiO{sub 2} passivation layer is developed. Besides evaluating feasible laser sources for this application, optimal process parameters are identified, ablation threshold fluencies are determined and the knowledge about the laser ablation of SiO{sub 2} layers on Si-substrates is enlarged. For characterizing the electrical properties of laser treated Si surfaces locally in the laser contact openings occurring emitter saturation current densities and surface recombination velocities are determined. Furthermore, a detailed analysis of the laser induced crystal damage by mea ns of microscopic investigation is performed. The impact of the laser damage on the efficiency of the RISE-EWT solar cell is experimentally demonstrated and considered by means of cell simulations.

  9. Temperature dependent electronic structure and magnetism of metallic systems with localized moments. Application on gadolinium; Temperaturabhaengige elektronische Struktur und Magnetismus von metallischen Systemen mit lokalisierten Momenten. Anwendung auf Gadolinium

    Energy Technology Data Exchange (ETDEWEB)

    Santos, C.A.M. dos

    2005-06-24

    This thesis focuses on the theoretical investigation of the temperature dependent electronic and magnetic properties of metallic 4f-systems with localized magnetic moments. The presented theory is based on the Kondo-lattice model, which describes the interaction between a system of 4f-localized magnetic moments and the itinerant conduction band electrons. This interaction is responsible for a remarkable temperature dependence of the electronic structure mainly induced by the subsystem of 4f-localized moments. The many-body problem provoked by the Kondo-lattice model is solved by using a moment conserving Green function technique, which takes care of several special limiting cases. This method reproduces the T=0-exact solvable limiting case of the ferromagnetically saturated semiconductor. The temperature dependent magnetic properties of the 4f-localized subsystem are evaluated by means of a modified Rudermann-Kittel-Kasuya-Yosida (RKKY) type procedure, which together with the solution of the electronic part allows for a self-consistent calculation of all the electronic and magnetic properties of the model. Results of model calculations allow to deduce the conditions for ferromagnetism in dependence of the electron density n, exchange coupling J and temperature T. The self-consistently calculated Curie temperature T{sub C} is presented and discussed in dependence of relevant parameters (J, n, and W) of the model. The second part of the thesis is concerned with the investigation of the temperature dependence of the electronic and magnetic properties of the rare-earth metal Gadolinium (Gd). The original Kondo-lattice model is extended to a multi-band Kondo-lattice model and combined with an ab-initio band structure calculation to take into account for the multi-bands in real systems. The single-particle energies of the model are taken from an augmented spherical wave (ASW) band structure calculation. The proposed method avoids the double counting of relevant interactions by exploiting the T=0-exact limiting case of the ferromagnetically saturated semiconductor and takes into account the correct symmetry of the atomic orbitals. The only parameter of the theory (inter-band exchange coupling J) is uniquely fixed by the band structure calculation. The self-consistently derived Curie temperature of 294.1 K and the T=0-magnetic moment of 7.71 {mu}{sub B} are surprisingly close to the experimental values. The induced temperature-dependence of the 5d conduction bands explains respective experimental photoemission data. (orig.)

  10. Herstellung substratgestützter, nanoporöser Aluminiumoxid-Template und ihre Anwendung für die Präparation von hocheffizienten SERS-Substraten

    OpenAIRE

    2014-01-01

    Nanostrukturen aus Gold und Silber haben sich als hochwirksame Substrate für die Oberflächenverstärkte Ramanspektroskopie (Surface Enhanced Raman Spectroscopy, SERS) erwiesen. Die hohe Verstärkung des elektromagnetischen Felds an solchen Strukturen erlaubt es, adsorbierte Moleküle in sehr geringer Konzentration bis hin zu einem Einzelmolekül mittels Ramanspektroskopie nachzuweisen und zu charakterisieren. Die praktische Umsetzung zu SERS-basierten Sensoren ist jedoch dadurch erschwert, dass e...

  11. Fabrication and examination of epitaxial HTSC/isolator thin films on sapphire substrates for application in high frequency devices; Herstellung und Untersuchung von epitaktischen HTSL/Isolator-Schichten auf Saphirsubstraten zur Anwendung in HF-Bauelementen

    Energy Technology Data Exchange (ETDEWEB)

    Kittel, H.

    1995-10-01

    The use of high temperature superconductors (HTSC) like YBCO with distinct lower surface resistance compared to normal conductors allows miniaturisation of high frequency (HF) circuits. The object of this work was the fabrication of YBCO thin films on low loss sapphire substrates applicable for stripline devices. To induce epitaxial growth and to avoid chemical reaction at the film-substrate boundary buffer layers were investigated. The examination of the growth properties and especially of the surface impedance has been allotted particular importance. In contrast to CaTiO{sub 3} it was possible to deposit CeO{sub 2}-buffer layers in direct growth up to a thickness of about 30 nm without cracks. The films show all growth properties required and even Laue-oscillations being a feature of high quality growth enabling the determination of film thickness distribution without destruction. The YBCO growth-, transport- and HF-properties meet the ones of YBCO films on standard substrates. A remarkable result is that the mosaic distribution of the CEO film, itself strongly dependend on film thickness, does not influence that of the YBCO film considerably. Rather it changes its shape subsequently due to YBCO deposition. A further particularity in contrast to deposition on standard substrates is the need to adjust the substrate heater tempeature for deposition of YBCO films with thicknesses {>=}300 nm needed for HF application. To demonstrate their usefullness some stripline devices like planar coils and side coupled filters have been fabricated and characterised. (orig.)

  12. Electron fields in clinical application. A comparison of pencil beam and Monte Carlo algorithm; Elektronenfelder in der klinischen Anwendung. Ein Vergleich von Pencil-Beam- und Monte-Carlo-Algorithmus

    Energy Technology Data Exchange (ETDEWEB)

    Treutwein, M.; Bogner, L. [Universitaetsklinikum Regensburg (Germany). Klinik und Poliklinik fuer Strahlentherapie

    2007-08-15

    Background and Purpose: For several years three-dimensional treatment-planning systems have used pencil beam algorithms in the calculation of electron fields. Nowadays, exact Monte Carlo methods are commercially available, showing good correspondence to experimental results. Clinical examples are investigated to find differences in the dose distribution of treatment plans, which are calculated with both pencil beam and Monte Carlo algorithm. Material and Methods: Two different clinical applications are regarded: (1) an irradiation of the chest wall, and (2) an electron field to the vertebral column. The dose distributions are calculated by Oncentra trademark MasterPlan on the one hand, using the Monte Carlo code VMC++, and by Helax trademark TMS on the other hand (both Nucletron B.V., Veenendaal, The Netherlands). Profiles and depth dose curves are evaluated by the Verisoft trademark program of PTW (Freiburg, Germany). Results: In the case of chest wall irradiation, the depth dose curves for the three investigated energies, 9, 15 and 21 MeV, agree rather well, also in lung tissue. The mean value for the lung differs only by 4% related to the dose maximum. In the case of vertebral column irradiation, however, the dose difference is more pronounced and, in the prevertebral region, is 56% lower for the VMC++ plan than in the pencil beam calculation. Conclusion: For irradiations of the chest wall, dose distribution calculations by means of pencil beam algorithm may be applied. Calculating electron dose distributions in cases of larger bone inhomogeneities, the more exact Monte Carlo algorithm should be preferred. (orig.)

  13. New certification process starts. Pt. 2. Application of Building Information Modeling (BIM) for the certification according to DGNB; Zertifizierungsprozess auf ''neuen Beinen''. T. 2. Anwendung von Building Informationen (BIM) zur Zertifizierung nach DGNB

    Energy Technology Data Exchange (ETDEWEB)

    Essig, Bernd [SCHOLZE Consulting GmbH, Leinfelden-Echterdingen (Germany). Geschaeftsbereich Ingenieur-Beratungsleistungen in Facility-, Informations-, Qualitaets-, Nachhaltigkeitsmanagement und Energieberatung; Ernst, Tatjana [SCHOLZE Consulting GmbH, Leinfelden-Echterdingen (Germany)

    2013-04-01

    The overall life cycle plays a significant role in the certification by German Sustainable Building Council (Stuttgart, Federal Republic of Germany). In order that certification becomes much more than only a documentation, comprehensive data are requested already in an early phase of planning. Early investigations of alternatives may have a significant influence on the life cycle of a building. But, from where do the auditors achieve these amounts of data without overcharging the partners involved in the planning process with questions. The Building Information Modelling contributes to the development of the future enhancement of process quality by an innovative information management.

  14. Mathematical modelling of dust samplers and application of the method to the gravimetric dust sampler RESPICON; Mathematische Modellierung von Staubmessgeraeten und Anwendung der Methode auf das gravimetrische Staubmessgeraet RESPICON

    Energy Technology Data Exchange (ETDEWEB)

    Armbruster, L. [Deutsche Montan Technologie GmbH, Essen (Germany). Gas and Fire Div.

    2004-07-01

    The evaluation and assessment of the fractionating particle sampler RESPICON due to the European test standard prEN 13205 has been continued by mathematical modelling of the candidate sampler and its response to different aerosols, characterized by the mean aerodynamic particle size (MMAD) and standard deviation (GSD). The three health related size fractions are sampled by the candidate sampler within the limits given by the standard, but correction factors for each fraction have to be taken into account. This result stands only for the use of the candidate as affixed point sampler. But due to the regulations in the standard it can be used as a personal sampler for windspeeds up to 2/ms. The investigations also have shown some disadvantages of the test standard itself, these should be eliminated in the future. (orig.)

  15. Organic semiconductors. Fundamental aspects of metal contacts, highly ordered films and the application in field effect transistors; Organische Halbleiter. Fundamentale Aspekte von Metallkontakten, hochgeordneten Schichten und deren Anwendung in Feldeffekttransistoren

    Energy Technology Data Exchange (ETDEWEB)

    Sachs, Soenke

    2010-05-31

    In this thesis, fundamental aspects of organic semiconductor devices are investigated and incorporated into the construction and optimization of an organic semiconductor field effect transistor (OFET). In order to approach the ''high end'' of OFETs, elaborate steps to optimize the devices are taken, despite the fact that they might not be feasible in a direct application. Well-characterized model systems are selected to study fundamental properties of devices, in particular the electronic structure at molecule/metal contacts and in the organic semiconductor bulk, as well as the growth of organic semiconductor molecules on single crystalline insulator substrates. The realization of a high performance OFET is pursued by a comprehensive approach in order to optimize particularly the interfaces of the device. Considerable progress is made towards a working OFET with best possible properties. A primary focus of this work, the investigation of the electronic structure at molecule/metal contacts and in the molecular bulk of the model system PTCDA/Ag(111) is performed using two photon photoelectron spectroscopy (2PPE). Of special interest is the excitation of the lowest unoccupied molecular orbital (LUMO) that shows different energetic relaxation mechanisms, depending on the origin of excitation. In addition to the importance of the molecule/metal contacts, the performance of OFETs is determined to a large extend by the quality of the organic semiconductor/gate insulator interface where the charge carrier channel is established. The morphology and structure of a molecular layer are investigated for diindenoperylene (DIP) molecules, adsorbed on a single crystalline Al{sub 2}O{sub 3} substrate, by atomic force microscopy and optical microscopy. Dependent on the substrate temperature during growth, the morphology shows grains with lateral dimensions of about 200 nm at 350 K which increase up to 700 nm at 450 K. This change in morphology is accompanied by an increase of roughness, indicating a change of the growth mode, at higher temperatures. At slightly higher temperatures of about 460 K, the growth of crystallites is observed. Depending on the particular preparation parameters, three different types of crystallites develop: mesa crystallites with lateral dimensions up to several microns, dendritic crystallites, characterized by kinetic growth processes, and layered crystallites, that are bent in three dimensions. Possibilities to utilize the grown crystallites in OFETs are discussed and the mesa type is found to be the most promising. The comprehensive concept for the development of a high performance OFET is introduced and refined in details. Improvements are made especially in the construction of the gate electrode that will be attached beneath the Al{sub 2}O{sub 3} substrate. To thin out the substrate, a drilling technique is improved and combined with wet chemical etching, resulting in gate insulator thicknesses below 10 {mu}m. On the basis of this preparatory work few first OFETs were built. As a first step towards the electrical characterization of DIP-OFETs, OFETs based on Silicon-oxide were successfully prepared and characterized. Moreover, present challenges and possible improvements towards a high performance OFET are discussed. (orig.)

  16. Minimally Invasive Procedures for Nasal Aesthetics

    OpenAIRE

    Alessio Redaelli; Pietro Limardo

    2012-01-01

    Nose has an important role in the aesthetics of face. It is easy to understand the reason of the major interest that has revolved around the correction of its imperfections for several centuries, or even from the ancient times. In the last decade, all the surgical or medical minimal-invasive techniques evolved exponentially. The techniques of rejuvenation and corrections of nasal imperfections did not escape this development that is much widespread in the medicine of the third millennium. In ...

  17. Plasmocitoma extramedular nasal en un perro

    Directory of Open Access Journals (Sweden)

    Carlos Giraldo M.

    2012-12-01

    Full Text Available Se describe un caso de plasmocitoma nasal en un canino, macho entero, de raza Akita de 30 Kg de peso y veintiún meses de edad, con historia de epistaxis unilateral crónica. Se practicó examen clínico y biopsia de la neoplasia visible en la cavidad nasal izquierda. La ubicación y extensión del tumor fue determinada mediante tomografía computarizada de cabeza y cuello. Se realizaron análisis histopatológico e inmunohistoquímico (IHQ del tejido tumoral. La tomografía computarizada evidenció una masa con densidad de tejido blando de 10 cm de longitud x 3.5 cm de diámetro y escasa captación de medio de contraste, que comprometía en su totalidad la cavidad nasal derecha y parte de la porción posterior de la coana izquierda. El análisis histopatológico reveló numerosas células redondas pleomórficas con poco citoplasma, rodeadas por trama escasa de tejido conectivo y bajo índice mitótico. En el examen IHQ la muestra fue negativa a los antígenos CD3 y CD20 para linfocitos T y B, respectivamente. Los hallazgos clínicos y de la tomografía computarizada, así como los resultados del análisis histopatológico del tejido tumoral, fueron compatibles con un plasmocitoma extramedular nasal de bajo grado de malignidad.

  18. Septum nasal perforation: treatments and literature' review

    OpenAIRE

    Martinez Neto, Eulógio Emílio; Dolci, Luiz Eduardo Lutaif; Murta, Alexandre Antonio; Zanini, Fábio Duro

    2010-01-01

    Introduction: The present study consists in a bibliographical' review concerning the articles related to the different manifestations and forms of the septum nasal perforation, with a main emphasis in the description of its techniques of surgical correction. As the etiology, that is fundamentally iatrogenic, accordingly surgical trauma. Other causes include exhibition to chemical industrial reagents, cocaine use, intranasal steroidal therapeutic, neoplasia and, infectious conditions. There is...

  19. BLIND NASAL INTUBATION IN CRANIOROFACIAL TRAUMA

    Directory of Open Access Journals (Sweden)

    K.R.DavidThakaran

    2013-09-01

    Full Text Available Restricted mouth opening presents one of the greatest challenges to the anesthetist for endotracheal intubation and ventilation. Awake blind nasal intubation has been one of the finest and favored techniques for intubation in previous decades for restricted mouth opening patients. A coordinated team approach, monitoring and adequate counseling of the patient is mandatory for the airway management to carry out a safe surgical procedure

  20. Minimally invasive procedures for nasal aesthetics

    Directory of Open Access Journals (Sweden)

    Alessio Redaelli

    2012-01-01

    Full Text Available Nose has an important role in the aesthetics of face. It is easy to understand the reason of the major interest that has revolved around the correction of its imperfections for several centuries, or even from the ancient times. In the last decade, all the surgical or medical minimal-invasive techniques evolved exponentially. The techniques of rejuvenation and corrections of nasal imperfections did not escape this development that is much widespread in the medicine of the third millennium. In many cases, the techniques of surgical correction involve invasive procedure that necessitates, for the majority of cases, hospitalisation. The author, using a different approach, has developed mini-invasive techniques using botulinum toxin A (BTxA and absorbable fillers for the correction of nasal imperfections. BTxA allows to reduce the imperfections due to hypertension of muscles, while the absorbable fillers allow to correct all the imperfections of the nasal profile from the root to the tip in total safety. The correction is based on the precise rules that allow avoiding the majority of side effects. Results are long lasting and well appreciated by patients.

  1. Minimally invasive procedures for nasal aesthetics.

    Science.gov (United States)

    Redaelli, Alessio; Limardo, Pietro

    2012-04-01

    Nose has an important role in the aesthetics of face. It is easy to understand the reason of the major interest that has revolved around the correction of its imperfections for several centuries, or even from the ancient times. In the last decade, all the surgical or medical minimal-invasive techniques evolved exponentially. The techniques of rejuvenation and corrections of nasal imperfections did not escape this development that is much widespread in the medicine of the third millennium. In many cases, the techniques of surgical correction involve invasive procedure that necessitates, for the majority of cases, hospitalisation. The author, using a different approach, has developed mini-invasive techniques using botulinum toxin A (BTxA) and absorbable fillers for the correction of nasal imperfections. BTxA allows to reduce the imperfections due to hypertension of muscles, while the absorbable fillers allow to correct all the imperfections of the nasal profile from the root to the tip in total safety. The correction is based on the precise rules that allow avoiding the majority of side effects. Results are long lasting and well appreciated by patients.

  2. The Usefulness of Nasal Packing with Vaseline Gauze and Airway Silicone Splint after Closed Reduction of Nasal Bone Fracture

    Directory of Open Access Journals (Sweden)

    Hyo Young Kim

    2012-11-01

    Full Text Available BackgroundPacking after closed reduction of a nasal bone fracture causes inconvenient nasal obstruction in patients. We packed the superior meatus with Vaseline gauze to support the nasal bone, and packed the middle nasal meatus with a Doyle Combo Splint consisting of an airway tube, a silastic sheet, and an expandable sponge to reduce the inconvenience. In addition, we aimed to objectively identify whether this method not only enables nasal respiration but also sufficiently supports the reduced nasal bone.MethodsNasal ventilation was measured via spirometry 1 day before surgery and compared to 1 day after surgery. To compare support of the reduced nasal bone by the 2 methods, 2 plastic surgeons assessed the displacementon X-rays taken after the surgery and after removing the packing. The extent of nasal obstruction, dry mouth, sleep disturbance, headache, and swallowing difficulty were compared with visual analog scales (VAS on a pre-discharge survey.ResultsIn the experimental group, the nasal respiration volume 1 day after surgery remained at 71.3%±6.84% on average compared to 1 day prior to surgery. Support of the reduced bone in the experimental group (2.80±0.4 was not significantly different from the control group (2.88±0.33. The VAS scores for all survey items were lower in the experimental group than in the control group, where a lower score indicated a lower level of inconvenience.ConclusionsThe nasal cavity packing described here maintained objective measures of nasal respiration and supported the reduced bone similar to conventional methods. Maintaining nasal respiration reduced the inconvenience to patients, which demonstrates that this packing method is useful.

  3. The Effect of Menstrual Cycle on Nasal Resonance Characteristics in Females

    Science.gov (United States)

    Kumar, Suman; Basu, Shriya; Sinha, Anisha; Chatterjee, Indranil

    2012-01-01

    The purpose of this study was to analyze resonance characteristics (nasality and nasalance values) during the menstrual cycle. Previous studies indicate changes in voice quality and nasal mucosa due to temporary falling estrogen levels in human females during their menstrual cycle. The present study compared the nasality and "nasalance scores"…

  4. The Effect of Menstrual Cycle on Nasal Resonance Characteristics in Females

    Science.gov (United States)

    Kumar, Suman; Basu, Shriya; Sinha, Anisha; Chatterjee, Indranil

    2012-01-01

    The purpose of this study was to analyze resonance characteristics (nasality and nasalance values) during the menstrual cycle. Previous studies indicate changes in voice quality and nasal mucosa due to temporary falling estrogen levels in human females during their menstrual cycle. The present study compared the nasality and "nasalance scores"…

  5. Objectivating nasality in healthy and velopharyngeal insufficient children with the Nasalance Acquisition System (NasalView). Defining minimal required speech tasks assessing normative values for Dutch language.

    Science.gov (United States)

    Hogen Esch, Thijs T; Dejonckere, Philippe H

    2004-08-01

    (1) To define normative nasalance data for Dutch language with "the NasalView System", and obtain a reference for normality when nasality is evaluated in children. (2) To investigate the minimal number of required speech tasks for a reliable nasalance measurement. 55 children (30 normal and 25 velopharyngeal insufficient), aged between 4 and 11 were included. All children had to read or repeat two Dutch passages ((one with a normal amount of nasal consonants (normal passage) and one with none (nonnasal passage)). Further, one normal and one velopharyngeal insufficient subject read a passage in repetition to test the NasalViews reproducibility: (1) For both passages, group means (GM) and standard deviations (S.D.) were used to compute "pathological nasalance boundaries" [GM +/- (2 x S.D.)], in combination with the coefficient of variation (CV), sensitivity, specificity and positive predictive values. (2) With ANOVA all sentences within each passage were tested for significant differences in nasalance. (1) The pathological boundaries were 28.6-41.4% (GM: 35.0) and 21.4-34.7% (GM: 28.1), for the normal and nonnasal passage, respectively. For the normal passage a sensitivity of 96%, a specificity of 93% and a positive predictive value of 92% was computed. For the nonnasal passage these parameters were 96, 95 and 96%, respectively. Intra subject CVs of 3.6% (normal subject) and 1.5% (VI subject) showed good reproducibility of measurements. (2) Within the normal passage only the third sentence was significantly different in nasalance, compared to the entire passage (31.2% versus 35.0%). Within the nonnasal passage the second and fifth sentences were significantly different (23.8 and 24.8% versus 28.1%). However, the individual nonsignificantly different sentences showed a higher variation in nasalance compared to the entire passages. The NasalView System seems to be reliable and quantifies valid nasalance values when nasality is evaluated. Within both passages high

  6. Chemical and mineralogical information as a standard for the evaluation of the quality of slags from thermal waste processing; Chemische und mineralogische Informationen als Bewertungsmassstab fuer die Qualitaet von Schlacken aus der thermischen Abfallverwertung. Pilot-Studie

    Energy Technology Data Exchange (ETDEWEB)

    Spiegel, W.; Huber, A.

    1996-12-31

    The main purpose of our investigations is to improve the knowledge about the physical and chemical conditions of waste ash by applying appropriate analytical techniques in order to have a better understanding of the reutilisation and long-term stability of waste ash. Of special interest are the heavy metals Copper, Lead and Zinc due to the fact that these elements are a main part of the leachable volume. A specific topic of our investigations is the test and application of new approaches for the characterization of municipal waste ash. This is done by the combination of: (I) A mineralogical way to describe the ash-system, (II) a reduction of complexity by separation of serveral fractions and (III) the application of specialized analytical methods. From fractionation specific fractions of a given grain size, susceptibility and density derived. The analysis of ash particles and single phases is done by statistical methods like optical microscopy, X-ray diffraction and scattered electron microscopy with an energy dispersive X-ray-fluorescene analysator. The main chemical components as well as the trace and ultratrace components are analized by neutron activation, wavelength dispersive X-ray fluorescence and sequential chemical extraction. (orig./HS) [Deutsch] Zielsetzung der Pilotstudie ist, durch Anwendung geeigneter Analysetechniken zu einer weiterfuehrenden Beschreibung des physikalischen und chemischen Zustands von HMV-Schlacken zu gelangen, um somit deren Wiederverwertbarkeit und Langzeitstabilitaet besser einschaetzen zu koennen. Besondere Beachtung finden die Metalle Kupfer, Blei und Zink, da fuer diese Elemente feststeht, dass sie einen wesentlichen Bestandteil des eluierbaren Potentials darstellen. Im vorliegenden Forschungsvorhaben werden neue Methodische Ansaetze zur Charakterisierung der HMV-Schlacke erprobt und umgesetzt. Tragende Saeulen sind dabei die mineralogische Betrachtungsweise des Stoffsystems, die Reduzierung der Komplexitaet durch Zerlegung in

  7. An MRI Von Economo - Koskinas atlas.

    Science.gov (United States)

    Scholtens, Lianne H; de Reus, Marcel A; de Lange, Siemon C; Schmidt, Ruben; van den Heuvel, Martijn P

    2016-12-28

    The cerebral cortex displays substantial variation in cellular architecture, a regional patterning that has been of great interest to anatomists for centuries. In 1925, Constantin von Economo and George Koskinas published a detailed atlas of the human cerebral cortex, describing a cytoarchitectonic division of the cortical mantle into over 40 distinct areas. Von Economo and Koskinas accompanied their seminal work with large photomicrographic plates of their histological slides, together with tables containing for each described region detailed morphological layer-specific information on neuronal count, neuron size and thickness of the cortical mantle. Here, we aimed to make this legacy data accessible and relatable to in vivo neuroimaging data by constructing a digital Von Economo - Koskinas atlas compatible with the widely used FreeSurfer software suite. In this technical note we describe the procedures used for manual segmentation of the Von Economo - Koskinas atlas onto individual T1 scans and the subsequent construction of the digital atlas. We provide the files needed to run the atlas on new FreeSurfer data, together with some simple code of how to apply the atlas to T1 scans within the FreeSurfer software suite. The digital Von Economo - Koskinas atlas is easily applicable to modern day anatomical MRI data and is made publicly available online.

  8. Positive Effekte von NSAR auf den Gastrointestinaltrakt

    Directory of Open Access Journals (Sweden)

    Lang M

    2015-01-01

    Full Text Available Ein protektiver Effekt von nichtsteroidalen Antirheumatika (NSAR auf die Tumorentstehung im Kolon wird in diversen präklinischen, epidemiologischen und auch randomisierten Arbeiten postuliert. Der Hauptwirkungsmechanismus von NSAR wird der Hemmung der Prostaglandinsynthese über die Cyclooxygenasen (COX zugeschrieben. Es existieren aber auch COX-unabhängige Mechanismen. Hier wollen wir einen Überblick über die Studienlage mit Aspirin, Sulindac und COX-2-Hemmern im Hinblick auf die Entstehung von Adenomen und Kolorektalkarzinomen geben. Die Wirkung dieser Substanzen ist besonders für Patienten mit familiärer Disposition relevant, aber auch für Patienten, die NSAR oder Aspirin aufgrund anderer Indikationen einnehmen. Es bestehen Abhängigkeiten von Dosis und Zeit sowie Interaktionen mit speziellen Mutationen (BRAF, PI3K und der zellulären COX-2-Expression. Beim Lynch-Syndrom ist die Wirksamkeit von Aspirin letztlich nicht sicher und eine multinationale klinische Studie mit 5-Aminosalizylsäure (Mesalazin wurde vom europäischen TRANSCAN-Programm gefördert.

  9. Resident aerobic microbiota of the adult human nasal cavity

    DEFF Research Database (Denmark)

    Rasmussen, TT; Kirkeby Nielsen, LP; Poulsen, Knud

    2000-01-01

    Recent evidence strongly suggests that the microbiota of the nasal cavity plays a crucial role in determining the reaction patterns of the mucosal and systemic immune system. However, little is known about the normal microbiota of the nasal cavity. The purpose of this study was to determine...... the microbiota in different parts of the nasal cavity and to develop and evaluate methods for this purpose. Samples were collected from 10 healthy adults by nasal washes and by swabbing of the mucosa through a sterile introduction device. Both methods gave results that were quantitatively and qualitatively...... reproducible, and revealed significant differences in the density of the nasal microbiota between individuals. The study revealed absence of gram-negative bacteria that are regular members of the commensal microbiota of the pharynx. Likewise, viridans type streptococci were sparsely represented. The nasal...

  10. [Language tests for the examination of nasal resonance].

    Science.gov (United States)

    Gasiorek, J; Pruszewicz, A; Obrebowski, A

    1996-01-01

    A set of 7 word tests with different number of nasal phonemes was prepared. These tests are adjusted to technical possibilities of nasal resonance examination by means of own construction apparatus. The VII-th test consisting only oral speech sounds appeared to be most important for estimating physiological nasal resonance characteristic for the Polish language and gave individual timbre of the voice. For Polish language these resonance rate is 15.2%. It is useful as reference data to evaluate patients with pathological nasal resonance. The VII-th test together with the V-th one which contain 6.3% of nasal consonants, and the VI-th with 33.3% of them were used for detailed evaluation of nasal resonance.

  11. Anatomical study of nasal cartilage in buffalo (Bubalus bubulus

    Directory of Open Access Journals (Sweden)

    Mahdi Yeganehzad

    2011-07-01

    Full Text Available This study used ten heads of adult buffalo taken from slaughterhouse. After transferring the samples to the anatomy hall, a split was carefully created on skin of muzzle and the skin was slowly separated from muscles and hypodermal connective tissue. Place of connection of cartilages to bone, cartilages to each other and shape of the cartilages were specified. In buffalo, nose apex has two nostrils fixed by bone and cartilage. After identifying and separating the cartilages, it was found that nasal cartilages in buffalo consisted of: 1 septum nasal located between two nostrils and reinforces it from inside. 2 dorso-lateral nasal cartilage constituting dorsal and lateral parts of the nostril. 3 ventro-lateral nasal cartilage constituting ventral and lateral parts of the nostril. 4 lateral accessory cartilage constituting lateral and ventral parts of the nostril. 5 medial accessory nasal cartilage located at Alar fold and connected to ventro-lateral nasal cartilage.

  12. Kartagener's syndrome presented with nasal obstruction: A case report

    Directory of Open Access Journals (Sweden)

    Suna Asilsoy

    2014-08-01

    Full Text Available The nasal polyposis is a chronic inflammatory process of the nasal mucosa. Although it is rare in children, there may be also association with cystic fibrosis and primary ciliary dyskinesia. About 50% of primary ciliary dyskinesia patients develop situs inversus and it is known as Kartagener's syndrome. The Kartagener's sydrome is a rare autosomal recessive disorder characterized by sinusitis, bronchiectasis, situs inversus. Clinically, patients present to the otolaryngologist with nasal obstruction. We as pediatricians, should consider nasal polyposis as a rare cause of nasal obstruction in children. In the presence of recurrent upper and lower respiratory tract infections accompanying nasal polyposis, Kartagener's syndrome must be kept in mind as a rare reason. [Cukurova Med J 2014; 39(4.000: 942-945

  13. Change in nasal congestion index after treatment in patients with chronic rhinosinusitis with nasal polyposis

    Science.gov (United States)

    Sahin-Onder, Serap; Oysu, Cagatay; Deveci, Ildem; Sahin, Samil; Aktas, Betul

    2016-01-01

    Background: The management of chronic rhinosinusitis with nasal polyposis (CRSwNP) involves both surgical and medical approaches, and remains a controversial subject. Objective: The objective of this prospective, randomized, controlled trial was to compare the medical and surgical treatments of CRSwNP in terms of their effect on the nasal congestion index (NCI). Methods: Forty-eight patients with CRSwNP were randomized either to medical or surgical therapy. Pretreatment and 3- and 6-month posttreatment assessments of the visual analog scale score, the 20-Item Sino-Nasal Outcome Test, saccharine clearance time, nasal endoscopy, and NCI measurement with acoustic rhinometry were performed. Forty-one subjects were included in the analysis. Results: Both the medical and surgical interventions for CRSwNP resulted in significant improvement in the visual analog scale score, 20-Item Sino-Nasal Outcome Test, saccharine clearance time, and nasal endoscopic examination scores. There was no difference between the two groups in terms of the percentage change from baseline for any of the parameters at the 6-month posttreatment assessment. NCI showed no significant difference from baseline. Similarly, no significant difference was found between the medical and surgical groups in terms of their effect on the NCI (p > 0.05). Conclusion: Because NCI does not correlate with standard subjective measures in outcomes for this group of patients, it cannot be used as an outcome measurement of treatment of subjects with CRSwNP. Results of this prospective randomized study did not find any additional benefit of surgical therapy over medical therapy in subjects with CRSwNP.

  14. Hydrocolloid dressing in preventing nasal trauma secondary to nasal continuous positive airway pressure in preterm infants.

    Science.gov (United States)

    Xie, Li-Hua

    2014-01-01

    Continuous positive airway pressure (CPAP) with nasal devices (nCPAP) is widely used in the respiratory management of newborns. The present study aimed to compare the incidence of nasal trauma secondary to nasal continuous positive airway pressure (nCPAP) protected with or without hydrocolloid dressing in preterm infants. This prospective controlled study was performed in the neonatal intensive care unit (NICU) of the Children's Hospital of Hunan Province from March 1, 2010 to June 31, 2010. A total of 65 infants, 46 males and 19 females, were recruited in this study. Their average gestational age was 32.6 weeks (range 28-37 weeks). The infants were randomly divided into clinical trial group (group A, n=33) and control group (group B, n=32). Paraffin oil was smeared around the nostrils before inserting prongs in group B; the infants in group A were covered on the infant's nostrils surface with hydrocolloid dressing (hydrocolloid dressing, 1.8 mm thick, 90029T, 3M Company, Minnesota, USA) with a size of 2-3 cm cutting two holes adapted to the nose and nostrils. The nostrils of those infants were inspected daily during nCPAP support until they were weaned off nCPAP. Nine infants (2 in group A and 7 in group B) developed nasal injury during nCPAP support. The Chi-square test revealed that there was a statistically significant difference (P=0.01) in the incidence of nasal injury between groups A and B. The study demonstrated that hydrocolloid dressing significantly decreased the incidence and the severity of nasal injury.

  15. Doença de von Willebrand e anestesia Enfermedad de von Willebrand y anestesia Von Willebrand's disease and anesthesia

    Directory of Open Access Journals (Sweden)

    Fabiano Timbó Barbosa

    2007-06-01

    Full Text Available JUSTIFICATIVA E OBJETIVOS: A doença de von Willebrand ocorre devido à mutação no cromossomo 12 e é caracterizada por deficiência qualitativa ou quantitativa do fator de von Willebrand. A diversidade de mutações leva ao aparecimento das mais variadas manifestações clínicas possibilitando a divisão dos pacientes em vários tipos e subtipos clínicos. A coagulopatia se manifesta basicamente através da disfunção plaquetária associada à diminuição dos níveis séricos do fator VIII coagulante. O objetivo dessa revisão foi mostrar os cuidados relacionados aos pacientes portadores da doença de von Willebrand durante o período perioperatório. CONTEÚDO: Foram definidas as características da doença de von Willebrand quanto à fisiopatologia, à classificação, ao diagnóstico laboratorial, ao tratamento atual e aos cuidados com o manuseio do paciente no período perioperatório. CONCLUSÕES: A doença de von Willebrand é o distúrbio hemorrágico hereditário mais comum, porém ela é subdiagnosticada pela complexidade da própria doença. A correta classificação do paciente, o uso apropriado da desmopressina e a transfusão do fator de von Willebrand são medidas fundamentais para a realização do procedimento anestésico bem-sucedido.JUSTIFICATIVA Y OBJETIVOS: La enfermedad de von Willebrand ocurre debido a la mutación en el cromosoma 12 y se caracteriza por la deficiencia cualitativa o cuantitativa del factor de von Willebrand. La diversidad de mutaciones conlleva al aparecimiento de las más variadas manifestaciones clínicas posibilitando la división de los pacientes en varios tipos y subtipos clínicos. La coagulopatía se manifiesta básicamente a través de la disfunción plaquetaria asociada con la disminución de los niveles séricos del factor VIII coagulante. El objetivo de esa revisión fue mostrar los cuidados relacionados con las pacientes portadoras de la enfermedad de von Willebrand durante el per

  16. Experience in the management of patients with nasal fractures.

    OpenAIRE

    Sahily Espino Otero; Julio Romero Rodrígez; Odalys Acevedo Sierra; Jorge Luis Estepa Pérez

    2009-01-01

    Background: Nasal fracture is the most frequent facial trauma; its immediate treatment help avoiding further complications. Objective: to characterize the patients with nasal fracture who meet the criteria for treatment. Method: An observational, descriptive study was developed, including all patients (114) of 15 years or more with nasal fracture received at the Emergency Maxilo-Facial Surgical Department in the provincial hospital of Cienfuegos from June 2006 to April 2007. The studies varia...

  17. Muscle-building therapy in treatment of nasal valve collapse.

    Science.gov (United States)

    Vaiman, Michael; Eviatar, Ephraim; Segal, Samuel

    2004-09-01

    The purpose of this paper is to describe the outcome of muscle-building therapy for nasal muscles in cases of nasal valve stenosis or collapse. The present study was performed to investigate the best way to combine transcutaneous and intranasal surface electromyography (sEMG) biofeedback training of muscles involved in nasal valve function with a home exercise program and electric stimulation of nasal muscles. A randomized pilot study of 3 groups of patients (n1=12, n2=12, n3=10; total 34 patients) presenting with symptoms of obstructed nasal breathing was conducted. All selected patients demonstrated nasal valve stenosis with a positive Cottler maneuver and clinically evident nasal valve collapse. Follow-up ranged from 8 to 12 months. Treatment for Group 1 included transcutaneous and intranasal electric stimulation of nasal muscles only. Treatment for Group 2 included biofeedback training and home exercise program of specific nasal movements, and treatment for Group 3 included surface and intranasal EMG biofeedback assisted specific strategies for nasal muscle education, home exercises and electric stimulation. All patients in these groups exhibited subjective improvement. For Group 3, in 80% the improvement was proved objectively; for Group 2, in 75% the improvement was proved objectively; for Group 1, in 58,33% the improvement was proved objectively. We found no significant difference between the results in Groups 3 and 2 and poorer results in Group 1. Relieve of nasal valve stenosis and collapse can be achieved with a complex muscle-building therapy as described. It helps a significant cohort of patients with symptoms of obstructed nasal breathing to avoid surgical intervention. Electric stimulation of the muscles does not contribute significantly in achieving of good results.

  18. Complex odontoma of the nasal cavity: a case report.

    Science.gov (United States)

    Soltan, Michelle; Kacker, Ashutosh

    2008-05-01

    We describe the case of a 76-year-old man who presented with symptoms of chronic nasal obstruction and recurrent sinusitis of many years' duration. The patient's history and radiographic findings established a diagnosis of a complex odontoma of the nasal cavity. The mass was surgically excised, and the diagnosis was confirmed by histopathology. The occurrence of an odontoma in the nasal cavity is extremely rare.

  19. Treatment of Rhinitis Sicca Anterior with Ectoine Containing Nasal Spray

    OpenAIRE

    Uwe Sonnemann; Olaf Scherner; Nina Werkhäuser

    2014-01-01

    Objectives. The safety and efficacy of ectoine nasal spray and ectoine nasal spray with dexpanthenol in the treatment of rhinitis sicca were evaluated in two studies. Design and Methods. Two noninterventional observational studies were performed to evaluate the efficacy and safety of a nasal spray containing ectoine (study 1) and ectoine/dexpanthenol (study 2) over a period of two weeks including comparable numbers of patients suffering from rhinitis sicca anterior. Patients and physicians we...

  20. Compressive and tensile mechanical properties of the porcine nasal septum

    OpenAIRE

    Al Dayeh, Ayman A.; HERRING, SUSAN W.

    2013-01-01

    The expanding nasal septal cartilage is believed to create a force that powers midfacial growth. In addition, the nasal septum is postulated to act as a mechanical strut that prevents the structural collapse of the face under masticatory loads. Both roles imply that the septum is subject to complex biomechanical loads during growth and mastication. The purpose of this study was to measure the mechanical properties of the nasal septum to determine (1) whether the cartilage is mechanically capa...

  1. Bau eines besseren Krankenhauses. Wertschöpfendes Management & Planung von Immobilien

    Directory of Open Access Journals (Sweden)

    Johan van der Zwart

    2015-06-01

    Full Text Available Die jüngste Deregulierung der Gesetze in den Niederlanden in Bezug auf Krankenhausimmobilien impliziert dass Institutionen der Gesundheitspflege mehr Möglichkeiten haben Einrichtungsentscheidungen zu treffen, wobei sie jedoch gleichzeitig selbst die Verantwortung für die Risiken in Verbindung mit den Investitionen übernehmen müssen. Zusätzlich wurden Einrichtungskosten integraler Bestandteil der Kosten der Gesundheitsversorgung. Dies gibt Aufschluss über die Angleichung zwischen der Organisation der Gesundheitspflege und der Einrichtung: Pflegeeinrichtungen selbst tragen das Risiko, ihre Investitionen in Immobilien auszugleichen, und hohe Einrichtungskosten führen zu höheren Gebührensätzen für die Gesundheitsvorsorge.In dieser Doktorarbeit werden die Ansichten und Konzepte des Corporate Real Estate Management (Immobilienmanagement von Unternehmen - CREM in Bezug auf den Beitrag untersucht, den sie zu dem Prozess der Einrichtungsentscheidung leisten können, unter Anwendung jüngster Fälle in niederländischen Krankenhäusern. CREM kann als das Management des Immobilienportfolios einer Gesellschaft durch Ausrichtung des Portfolios und der Dienstleistungen mit den Bedürfnissen des Kerngeschäfts definiert werden, um maximalen Mehrwert für das Geschäft und einen optimalen Beitrag zu der Gesamtleistung der Organisation zu erhalten. Diese Definition geht davon aus, dass die Einrichtung der Organisation einen Mehrwert geben und zu ihrer Gesamtleistung beitragen kann. Es ist daher für diese Untersuchung von zentraler Bedeutung, den Mehrwert einer Immobilie zusätzlich zur Bewertung dieser Mehrwerte näher auszuführen und sie für das Krankenhausmanagement anwendbar zu machen. Diese Mehrwerte bestimmen den Übergang zwischen den unterschiedlichen Phasen in dem Zyklus der Initiierung, der Planung, der Konstruktion und Belegung der Einrichtung. Zusätzlich funktioniert der Mehrwert der Immobilie als eine gemeinsame Sprache zwischen den

  2. Kerttu Wagner. Die historischen romane von Jaan Kross / Wolfgang Drechsler

    Index Scriptorium Estoniae

    Drechsler, Wolfgang, 1963-

    2001-01-01

    Arvustus: Wagner, Kerttu. Die historischen Romane von Jaan Kross : am Beispiel einer Untersuchung der deutschen und englischen Übersetzungen von "Professor Martensi ärasõit" (1984). Frankfurt am Main [etc.] : P. Lang, 2001.

  3. Kerttu Wagner. Die historischen romane von Jaan Kross / Wolfgang Drechsler

    Index Scriptorium Estoniae

    Drechsler, Wolfgang, 1963-

    2001-01-01

    Arvustus: Wagner, Kerttu. Die historischen Romane von Jaan Kross : am Beispiel einer Untersuchung der deutschen und englischen Übersetzungen von "Professor Martensi ärasõit" (1984). Frankfurt am Main [etc.] : P. Lang, 2001.

  4. Von Willebrand's disease: case report and review of literature ...

    African Journals Online (AJOL)

    Abstract. Von Willebrand Disease (VWD) is the most common human ... The most bleeding forms of VWD usually do not concern type 1 patients with the ... and collagen binding test and genanalysis allow diagnosing the different types of von.

  5. Gemeinsam hilfreich oder einsam lästig? Beurteilung von praktikumsbegleitenden Weblogs von angehenden Lehrpersonen

    Directory of Open Access Journals (Sweden)

    Nives Egger

    2017-02-01

    Full Text Available Weblogs werden an Hochschulen vermehrt zur Unterstützung von Lern- und Reflexionsprozessen eingesetzt, in der Lehrer/innenbildung auch zunehmend während der berufspraktischen Ausbildung. Die Studierenden beurteilen den Einsatz von Weblogs jedoch unterschiedlich. Dabei ist wenig bekannt, welchen Einfluss die Vergabe und das Erhalten von Peerfeedback auf den Beurteilungsprozess von praktikumsbegleitenden Weblogs sowie auf den Umfang von Blogpostings haben. Im folgenden Beitrag wird dieser Frage mittels einer Befragung von 74 angehenden Lehrpersonen nachgegangen, die praktikumsbegleitende Weblogs mit oder ohne Peerfeedback nutzten, um über herausfordernde Ereignisse im Praktikum zu reflektieren. Die Ergebnisse zeigen, dass Studierende, die Peerfeedback erhielten und andere Blogbeiträge kommentierten, den Weblogeinsatz nützlicher einschätzen sowie eine höhere Motivation und positivere Einstellung gegenüber den Einsatz von Weblogs aufweisen als Studierende, die ohne Peerfeedback bloggen. Keinen Einfluss hat Peerfeedback auf den Umfang der Blogbeiträge und auf die dafür aufgewendete Zeit.

  6. Energetic assessment of HFC-blends as R 22 alternatives; Energetische Bewertung von FKW-Gemischen als R 22-Alternativen

    Energy Technology Data Exchange (ETDEWEB)

    Ahnefeld, G. [Inst. fuer Luft- und Kaeltetehnik gem.GmbH, Dresden (Germany); Vollmer, D. [Inst. fuer Luft- und Kaeltetehnik gem.GmbH, Dresden (Germany); Wobst, E. [Inst. fuer Luft- und Kaeltetehnik gem.GmbH, Dresden (Germany)

    1996-05-01

    Available with ILK is an HFC, HFC-blend test rig, which can be used for testing of refrigerant compressors as well as for industrial plant tests under nearly practical conditions. As compared with R 22, performance measurements of plants operated with the HFC-blends R 407C, R 407A, R 407B, R 404A and R 507 under constant external conditions (temperature difference 5 K between refrigerant/heat carrier, constant refrigerating capacity) showed losses up to 20% for the coefficient of performance. The highest deviations between theoretical cycle calculations and experimental results were obtained on R 407C and R 407A. One reason is an increased temperature glide of the condensing refrigerant caused by pressure drop and subcooling. Energetic benefits can be achieved through installation of an internal heat exchanger at blends with a higher R 125 content (R 407B, R 404A, R 507). (orig.) [Deutsch] Mit der FKW-, FKW-Gemisch-Experimentieranlage steht im ILK eine Versuchseinrichtung zur Verfuegung, die sowohl fuer Verdichterleistungsmessungen als auch fuer anlagentechnische Untersuchungen unter praxisnahen Bedingungen geeignet ist. Anlagenleistungsmessungen mit den zeotropen FKW-Gemischen R 407C, R 407A, R 407B und R 404A sowie dem azeotropen Gemisch R 507 haben bei konstanten aeusseren Bedingungen (Temperaturspreizung des Kaelte-/Waermetragers 5 K, konstante Kaelteleistung) Leistungszahleinbussen bis zu 20% im Vergleich zu R 22 ergeben. Bei R 407C und R 407A weichen die Werte besonders stark von theoretischen Vorausberechnungen (Kreisprozess) ab. Eine wesentliche Ursache ist die durch Druckverlust und Unterkuehlung vergroesserte Temperaturaenderung im Verfluessiger. Vom LORENZ-Prozess ist bekannt, dass zusaetzliche Verluste auftreten, wenn die Temperaturaenderung des zeotropen Kaeltemittelgemisches groesser als die Temperaturspreizung des aeusseren Stoffstromes ist. Auch eine wesentliche Flaechenvergroesserung fuehrt dann nur zu geringen Verbesserungen. Die Anwendung des

  7. Patient experience with mupirocin or povidone-iodine nasal decolonization.

    Science.gov (United States)

    Maslow, Jed; Hutzler, Lorraine; Cuff, Germaine; Rosenberg, Andrew; Phillips, Michael; Bosco, Joseph

    2014-06-01

    Led by the federal government, the payers of health care are enacting policies designed to base provider reimbursement on the quality of care they render. This study evaluated and compared patient experiences and satisfaction with nasal decolonization with either nasal povidone-iodine (PI) or nasal mupirocin ointment (MO). A total of 1903 patients were randomized to undergo preoperative nasal decolonization with either nasal MO or PI solution. All randomized patients were also given 2% chlorhexidine gluconate topical wipes. Patients were interviewed prior to discharge to assess adverse events and patient experience with their assigned preoperative antiseptic protocol. Of the 1903 randomized patients, 1679 (88.1%) were interviewed prior to discharge. Of patients receiving PI, 3.4% reported an unpleasant or very unpleasant experience, compared with 38.8% of those using nasal MO (P.05). Being recruited as an active participant in surgical site infection prevention was a positive experience for 87.2% of MO patients and 86.3% of PI patients (P=.652). Those assigned to receive PI solution preoperatively reported significantly fewer adverse events than the nasal MO group (P<.01). Preoperative nasal decolonization with either nasal PI or MO was considered somewhat or very helpful by more than two-thirds of patients. Copyright 2014, SLACK Incorporated.

  8. Nasal air conditioning in relation to acoustic rhinometry values.

    Science.gov (United States)

    Lindemann, Joerg; Tsakiropoulou, Evangelia; Keck, Tilman; Leiacker, Richard; Wiesmiller, Kerstin M

    2009-01-01

    Changes of nasal dimensions can influence the air-conditioning capacity of the nose because of alterations of airflow patterns. The goal of this study was to evaluate the correlation between intranasal temperature and humidity values and nasal dimensions, assessed by means of acoustic rhinometry. Eighty healthy volunteers (40 men and 40 women; median age, 51 years; range, 20-84 years) were enrolled in the study. In total, 160 nasal cavities were examined. All volunteers underwent a standardized acoustic rhinometry. Additionally, intranasal air temperature and humidity measurements at defined intranasal detection sites within the anterior nasal segment were performed. There was no statistically significant difference between the right and left side of the nose regarding air temperature, absolute humidity, and acoustic rhinometric values. A negative correlation was established between the rhinometric nasal volumes/minimal cross-sectional areas and air temperature and absolute humidity values at the three intranasal detection sites. According to our results, nasal volumes and cross- sectional areas relevantly influence nasal air conditioning. A healthy nasal cavity with smaller volumes and cross-sectional areas seems to present a more effective air-conditioning function than a too "wide" open nose because of changes in airflow patterns. This observation should be considered as a limitation for overly extensive nasal surgery especially of the turbinates.

  9. STRATEGIES AND PROSPECTS OF NASAL DRUG DELIVERY SYSTEMS

    Directory of Open Access Journals (Sweden)

    Gannu Praveen Kumar

    2012-03-01

    Full Text Available The recent advancement of nasal drug delivery systems has increased enormously and is gaining significant importance. Intranasal therapy has been an accepted form of treatment in the Ayurvedic system of Indian Medicine. The non-invasive delivery of nasal drug delivery systems made to exploit for the development of successful treatment. The advantages, disadvantages, mechanism of action and application of nasal drug delivery system in local delivery, systematic delivery, nasal vaccines and CNS delivery are explained lucidly. The relevant aspects of biological, physicochemical and pharmaceutical factors of nasal cavity that must be considered during the process of discovery and development of new drugs for nasal delivery as well as in their incorporation into appropriate nasal pharmaceutical formulations are also discussed. Nasal route is more suitable for those drugs which cannot be administered orally due to gastric degradation or hepatic first pass metabolism of the drug. Intranasal drug delivery is found much promising route for administration of peptides and protein drugs. Much has been investigated and much more are to be investigated for the recent advancement of nasal drug delivery systems.

  10. Nasal and paranasal involvement in primary Sjogren`s syndrome.

    Science.gov (United States)

    Midilli, R; Gode, S; Oder, G; Kabasakal, Y; Karci, B

    2013-09-01

    The aim of this study is to investigate nasal and paranasal signs and symptoms of the primary Sjogren`s syndrome patients and compare them with healthy controls. Seventy-seven (7 M, 70 F) primary Sjogren`s syndrome patients and 77 healthy controls were included in the study. Anterior rhinoscopy, nasal endoscopy, 5 component smell discrimination test, nasal clearance analysis with saccharin test and electrorhinomanometer were performed. Nasal crusting was present in 31 and 24 individuals in patient and control groups, respectively. Sinusitis was present in 2 and 1 individuals in patient and control groups, respectively. Nasal polyposis was present in 7 and 1 individuals in patient and control groups, respectively. These differences were not statistically different. Although there were some findings in a few patients, nasal findings were insignificant and mild even in patients with severe oral or ocular findings. Rhinomanometry, nasal clearance determination or smell discrimination tests have very little value in the diagnosis or management of primary Sjogren`s syndrome. Nasal polyposis was higher in the patient group, though it did not reach a significant level. Nasal glandular involvement is mild and insignificant in primary Sjogren`s syndrome.

  11. Liouville-von Neumann molecular dynamics

    Science.gov (United States)

    Jakowski, Jacek; Morokuma, Keiji

    2009-06-01

    We present a novel first principles molecular dynamics scheme, called Liouville-von Neumann molecular dynamics, based on Liouville-von Neumann equation for density matrices propagation and Magnus expansion of the time-evolution operator. The scheme combines formally accurate quantum propagation of electrons represented via density matrices and a classical propagation of nuclei. The method requires a few iterations per each time step where the Fock operator is formed and von Neumann equation is integrated. The algorithm (a) is free of constraint and fictitious parameters, (b) avoids diagonalization of the Fock operator, and (c) can be used in the case of fractional occupation as in metallic systems. The algorithm is very stable, and has a very good conservation of energy even in cases when a good quality conventional Born-Oppenheimer molecular dynamics trajectories is difficult to obtain. Test simulations include initial phase of fullerene formation from gaseous C2 and retinal system.

  12. Gasification of liquid manure; Vergasung von Guelle

    Energy Technology Data Exchange (ETDEWEB)

    Gudenau, H.W.; Hoberg, H.; Hirsch, U. [Technische Hochschule Aachen (Germany). Inst. fuer Eisenhuettenkunde

    1996-12-31

    The potential of thermal use of liquid manure is investigated. It is recommended to separate the liquid and solid fraction. While the liquid fraction can be used as fertilizer, the solid fraction can be used for generating a fuel gas for combined heat and power generation. (orig) [Deutsch] Die Untersuchungen haben ergeben, dass in der thermischen Verwertung von Guelle ein bisher nur wenig genutztes Potential vorliegt. Die zum Anbau von Getreide notwendige Duengung kann durch Separation von Guelle in Fest- und Duennfraktion effektiver und kostenguenstiger durchgefuehrt werden. Der Naehrstoffgehalt des Guellefeststoffs sollte durch thermische Aufbereitung aufkonzentriert werden, so dass eine Vermarktung auch mit laengeren Transpoertwegen darstellbar ist. Die bei der thermischen Behandlung gewonnene Waerme kann prozessintern genutzt und ueberschuessige Waerme an Abnehmer in der naeheren Umgebung geliefert werden. Genauso besteht die Moeglichkeit, ein Brenngas zu erzeugen und die Energie mit Kraft-Waerme-Kopplung zu nutzen. (orig)

  13. Wireless energy transmission through the abdominal wall for operating implanted actuators and recharging implanted energy storages with due consideration to the simultaneous undisturbed transcutaneous transmission of encoded signals for controlling various functions of the implant; Drahtloser Energietransfer durch die Bauchdecke zum Betrieb von implantierten Aktoren und zur Wiederaufladung von implantierten Energiespeichern unter Beruecksichtigung der gleichzeitigen ungestoerten transkutanen Uebertragung von codierten Signalen zur Steuerung verschiedener Funktionen eines Implantats

    Energy Technology Data Exchange (ETDEWEB)

    Peter, S.

    2007-07-01

    integrierten Energiespeicher damit geladen werden koennen, ohne Energieleitungen durch die Bauchdecke hindurch fuehren zu muessen. Dieses ziel wurde durch die Entwicklung und Anwendung eines auf die Anforderungen im urologischen Bereich eingesetzten medicinischen Implantats abgestimmten induktiven und damit transkutanen Energietransfer realisiert. Dazu wurde unter anderem ein umfangreiches Simulationsmodell zur Berechnung mit der Finiten-Element-Methode erstellt. Als Resultat ergeben sich eine Reihe von Vorteilen fuer die betroffenen Patienten: vollstaendige Vermeidung von Infektionen die sonst durch eine staendig offene ''Wunde'' in der Bauchdecke, bedingt durch die hindurch tretende Energieleitung, vorhanden waere; hierdurch ergibt sich wiederum der Vorteil, dass die Patienten weniger Medikamente zu sich nehmen muessen und die Kosten fuer eine staendige Wundbehandlung entfallen; weitestgehende Unabhaengigkeit von der stationaeren Energieversorgung im Betrieb des Systems (ueber mehrere Tage keine Notwendigkeit staendig eine Netzsteckdose in der Naehe haben zu muessen), damit geht eine wesentlich gesteigerte Mobilitaet der Patienten einher. Die Entwicklung einer transkutanen Signaluebertragung mit Hilfe von Infrarot bzw. RF Technologie hat die Rueckgewinnung einer willentlichen Steuerung der Miktion erst entscheidend ermoeglicht und beseitigt damit eine der Hauptaengste von betroffenen Patienten, ein fremdbestimmtes und durch ein von kurzen festgelegten Intervallen wiederkehrender Entleerungstaetigkeit (rund um die Uhr) gepraegtes Leben fuehren zu muessen. Die zusaetzliche Abfragemoeglichkeit des Reservoirfuellstandes ermoeglicht dabei eine Kontrolle zu beliebigen Zeitpunkten und fuehrt deshalb zu einer entscheidend verbesserten Planbarkeit der Toilettengaenge. Dies stellte das zweite Ziel dar. Die Kombination des transkutanen Energie- und Signaltransfers fuehrte u.a. zu einem Gesamtsystem, das die Lebensqualitaet der von einer Totaloperation betroffenen

  14. Multivariate Herkunftsanalyse von Marmor auf petrographischer und geochemischer Basis

    OpenAIRE

    Cramer, Thomas

    2004-01-01

    Am Beispiel von aus Kleinasien stammenden Grabungsfunden in der Antikensammlung Berlin wird die Methodik der Herkunftsanalyse von Marmoren, d.h. der Zuordnung zu ihren Lagerstätten, weiterentwickelt und erprobt. Dazu wird der aktuelle Forschungsstand kritisch gewürdigt, die Voraussetzungen, Bedingungen und Grenzen der Provenienzbestimmung werden systematisiert und von den zahlreichen Gesteinsmerkmalen und Untersuchungsmethoden die geeignetsten ausgewählt. Marmore von 38 Sammlungsobjekten, die...

  15. Experimentelle Untersuchung von Konzentrations- und Verweilzeiteffekten in Membranreaktoren

    OpenAIRE

    Tota, A.; Hamel, C.; Thomas, S.; Joshi, M.; Klose, F.; Seidel-Morgenstern, A.

    2003-01-01

    Heterogen katalysierte Oxidationsreaktionen von kurzkettigen Kohlenwasserstoffen werden in der Industrie zur Erzeugung von Ausgangsmaterialien für wertvollere Syntheseprodukte (selektive Oxidation) oder zur Entsorgung von Abgasen eingesetzt. Bei selektiven Oxidationen ist das gewünschte Produkt gewöhnlich ein thermodynamisch instabiles Zwischenprodukt. Mit dem Einsatz von Membranreaktoren verspricht man sich hohe Selektivitäten. bei gleichzeitig hohen Ausbeuten. Als Modellreaktion für systema...

  16. Analyse und Vergleich von nativer Entwicklung auf dem Android-Betriebssytem mit der plattformunabhängigen Entwicklung mit dem Titanium SDK am Beispiel des Mobile SQL-Trainers

    OpenAIRE

    Spies, Matthias (Bachelor Informatik)

    2013-01-01

    Es wurde ein Vergleich zwischen einer nativen Android-Anwendung und einer Titanium-Anwendung durchgeführt, anhand einen mobilen SQL-Trainers. Die mit Eclipse nativ entwickelte Android-Anwendung und die Titanium-Anwendung (Android und iOS) sind, zumindest mit unserem beispielhaften Funktionsumfang, fast gleichwertig. Die Entwicklung für BlackBerry und Tizen konnte auf Grund der noch nicht ausgereiften Entwicklungsart für diese Plattformen kaum getestet werden, allerdings wird der größere App-M...

  17. Experience in the management of patients with nasal fractures. Experiencia en el manejo de los pacientes con fracturas nasales.

    OpenAIRE

    2009-01-01

    Background: Nasal fracture is the most frequent facial trauma; its immediate treatment help avoiding further complications. Objective: to characterize the patients with nasal fracture who meet the criteria for treatment. Method: An observational, descriptive study was developed, including all patients (114) of 15 years or more with nasal fracture received at the Emergency Maxilo-Facial Surgical Department i...

  18. THE CORRELATION BETWEEN DERIVED NASALANCE MEASURES AND PERCEIVED NASALITY IN CHILDREN WITH REPAIRED CLEFT LIP AND PALATE

    Directory of Open Access Journals (Sweden)

    Attuluri Navya

    2014-04-01

    Full Text Available Context: Velopharyngeal dysfunction (VPD is one of the associated condition reported in individuals with repaired cleft lip and palate (RCLP leading to hypernasality. Nasality can be assessed by nasometer through nasalance values. But, mean nasalance values (N found to be overlapping between individuals with RCLP and normals. To overcome these limitations Nasalance Distance (ND and Nasalance Ratio (NR are derived based on nasalance range. Aims: The study is aimed to evaluate, correlate and compare acoustical (N, ND & NR and perceptual measures of nasality between the children with RCLP and control group. Settings and Design: Institutional setup and standard group comparison design Methods and Material: The study included fifteen children with RCLP ranging from 6 to 11 years and the control group consists of age and gender matched 15 typically developing children. Four point standard rating scale was used to rate the hypernasality by three speech language pathologists (SLP’s and Nasometer was used to measure the mean and derived nasalance scores for vowels and sentences in Kannada. Statistical analysis: SPSS, Cronbach’s Alpha test, multivariate analysis and Pearson’s product movement correlation were used to analyze the data. Results: Significant increase in the mean nasalance value and NR was seen in children with RCLP than the control group, whereas ND was contrary. ND was highly correlated with perceived nasality than N. The NR of sentences shows high negative correlation. Conclusions: The measures based on range of nasalance can be adapted to the routine clinical examinations for better correlation with perceived nasality.

  19. The application of the fluorescence procedure for the determination of local lubricant film thicknesses; Die Anwendung des Fluoreszenzverfahrens zur Bestimmung lokaler Schmierfilmdicken

    Energy Technology Data Exchange (ETDEWEB)

    Hermann, H.; Hildebrand, M. [Technische Univ. Bergakademie Freiberg (Germany). Inst. fuer Metallformung

    2002-01-01

    The analysis of the friction and lubrication during the deformation of metals requires the determination of local lubricant film thicknesses. For this purpose the fluorescence procedure was used by the excitation with lasers. The aspired high local resolution could not be realized due to photolysis of the dye. A measuring spot of a minimum size of 1.5 x 1.5 mm was reached for the measurement of lubricant film thicknesses up to 5 {mu}m with a luminescence scanner. (orig.) [German] Die Analyse der Reibung und Schmierung in der Umformung von Metallen erfordert die Bestimmung lokaler Schmierfilmdicken. Dazu wurde das Fluoreszenzverfahren mit Anregung durch Laser angewendet. Die angestrebte hohe oertliche Aufloesung konnte infolge Fotolyse des Farbstoffes nicht realisiert werden. Mit einem Lumineszenztaster konnte ein Messfleck mit einer minimalen Groesse von 1,5 x 1,5 mm bei Schmierfilmdicken bis zu 5 {mu}m erreicht werden. (orig.)

  20. Approximate equivalence in von Neumann algebras

    Institute of Scientific and Technical Information of China (English)

    DING; Huiru; Don; Hadwin

    2005-01-01

    One formulation of D. Voiculescu's theorem on approximate unitary equivalence is that two unital representations π and ρ of a separable C*-algebra are approximately unitarily equivalent if and only if rank o π = rank o ρ. We study the analog when the ranges of π and ρ are contained in a von Neumann algebra R, the unitaries inducing the approximate equivalence must come from R, and "rank" is replaced with "R-rank" (defined as the Murray-von Neumann equivalence of the range projection).

  1. Von Mumien, Cyborgs und Röntgenbildern

    Directory of Open Access Journals (Sweden)

    Regina Schleicher

    2004-03-01

    Full Text Available Unter dem Titel Techniken der Reproduktion liegt ein Sammelband vor, der die Beiträge einer Tagung an der Universität Paderborn vom Dezember 2001 enthält. In enger Verknüpfung verschiedener disziplinärer Perspektiven werden Schlaglichter auf eine Vielzahl von Themen geworfen, die sich mit dem Begriff „Reproduktion“ verbinden. Dabei wird deutlich, wie eng die Geschichte der Medien und die Entwicklung von Technologien der biologischen Fortpflanzung miteinander verzahnt sind.

  2. Verwertung von Prozessbieren in der Brauerei

    OpenAIRE

    Schneeberger, Mark

    2007-01-01

    Die betriebsinterne Verwertung von Prozessbieren (PB) zur Minimierung des Bierschwandes stellt den Kern der Arbeit dar. Als mengenmäßig bedeutsamste PB haben sich Hefebiere (HB), Vor-, Zwischen- und Nachläufe (VZNL) aus der Filtration, Biere aus unterfüllten bzw. falsch etikettierten Flaschen aus der Abfüllung sowie Rückbiere herausgestellt. Verschiedene Indikatoren in Hefezellen und im HB wurden zur Kontrolle von Hefebierrückgewinnungsanlagen ermittelt. Um eine hohe Qualität der wiedergewinn...

  3. [Anja Wilhelmi. Lebensweltlen von Frauen der deutschen Oberschicht im Baltikum (1800-1939). Eine Untersuchung anhand von Autobiographien] / Alexander Ewig

    Index Scriptorium Estoniae

    Ewig, Alexander, 1980-

    2011-01-01

    Arvustus: Wilhelmi, Anja. Lebenswelten von Frauen der deutschen Oberschicht im Baltikum (1800-1939). Eine Untersuchung anhand von Autobiographien. (Veröffentlichungen des Nordost-Instituts, 10.) (Wiesbaden : HArrassowitz 2008)

  4. [Anja Wilhelmi. Lebensweltlen von Frauen der deutschen Oberschicht im Baltikum (1800-1939). Eine Untersuchung anhand von Autobiographien] / Alexander Ewig

    Index Scriptorium Estoniae

    Ewig, Alexander, 1980-

    2011-01-01

    Arvustus: Wilhelmi, Anja. Lebenswelten von Frauen der deutschen Oberschicht im Baltikum (1800-1939). Eine Untersuchung anhand von Autobiographien. (Veröffentlichungen des Nordost-Instituts, 10.) (Wiesbaden : HArrassowitz 2008)

  5. Analysis of sulfonylurea herbicides in water by ion-pair chromatography; Analytik von Sulfonylharnstoff-Herbiziden in Wasser mit der Ionenpaarchromatographie

    Energy Technology Data Exchange (ETDEWEB)

    Mueller, I.A.; Wacht, U. [Hydrologische Untersuchungsstelle Salzburg (Austria)

    1997-11-01

    -methyl sowie Thifensulfuron-methyl koennen von Tribenuron-methyl chromatographisch nicht unterschieden werden. Die IPC verfuegt ueber eine sehr gute Trennleistung und erreicht Nachweisgrenzen von 15 bis 20 ng/ml fuer saemtliche hier untersuchten Wirkstoffe. Versuche zur Anreicherung der Wirkstoffe bei verschiedenen pH-Werten im Bereich von 2 bis 10 sowie bei unterschiedlichen Standzeiten unter Einfluss von pH=2 und 5 wurden durchgefuehrt. Es ergab sich eine eindeutige Abhaengigkeit der Wiederfindungsraten (WFR) vom ionischen Charakter und der Hydrolysestabilitaet. Daraus sind verschiedene Anreicherungsstrategien abzuleiten. Die Anreicherung der Wirkstoffe wurde vergleichend mittels Fluessig/fluessig-Extraktion (LPE) und Festphasen-Extraktion (SPE) an C{sub 18}-Material getestet. Bei Anwendung der SPE-Saeulen wird bei pH=6 optimal angereichert. Es ergaben sich Wiederfindungsraten (WFR) von 58 bis 107%. Fuer die LPE liegt das Optimum bei pH=5. Versuche mit dotierten Teichwasserproben einer Golfanlage mittels LPE und SPE ergaben eine Matrixabhaengigkeit der WFR. (orig.)

  6. The effect of nasalization on /a/ vowel formants before and after nasal consonant in 4-9-year old normal Persian speaking children

    Directory of Open Access Journals (Sweden)

    Kowsar Baghban

    2014-01-01

    Full Text Available Background and Aim : Nasalization of a vowel refers to the addition of nasal resonance to the vocal tract transfer function. Also, vowel nasalization occurs because of coarticulation. Coupling of the nasal resonating space to the oropharyngeal cavity alters the vocal tract formants in complex ways. The purpose of this study was to investigate the effect of nasalization on /a/ vowel formants in before and after nasal consonant.Methods: In current cross-sectional study, voice samples of 60 normal children ranging the age of four-nine years were investigated. Participants were asked to repeat / ʔ ama/ three times and vowel /a/ after presentation of an auditory model. Then, obtained samples were analyzed using Praat 5.3.13 . Average of F0, F1, F2 and F3 were calculated for /a/ comes before and after /m/ in production of / ʔ ama/ over three trials.Results: There were statistically significant differences of F1, F2 and F3 between / a/ which proceeds nasal consonant and /a/ follows nasal consonant , the before nasal consonant /a/ versus single /a/ and the after nasal consonant /a/ versus single /a/ (p=0.001 for all.Conclusion : F1, F2 and F3 in /a/ before nasal consonant affected by anticipatory nasal coarticulation and in /a/ after nasal consonant affected by carry-over nasal coarticulation . This study showed nasal coarticulation and nasalization result in decreasing F1, F2 and F3 in /a/ vowel.

  7. Randomized trial of prongs or mask for nasal continuous positive airway pressure in preterm infants.

    LENUS (Irish Health Repository)

    Kieran, Emily A

    2012-11-01

    To determine whether nasal continuous positive airway pressure (NCPAP) given with nasal prongs compared with nasal mask reduces the rate of intubation and mechanical ventilation in preterm infants within 72 hours of starting therapy.

  8. Implementierung eines Rolling Horizon Ansatzes zur Anwendung bei der Lokomotiveneinsatzoptimierung (Implementation of a Rolling Horizon Approach to its Application for Locomotive Scheduling)

    Science.gov (United States)

    2016-01-01

    298 (Rev. 2-8~~) Prescribed by ANSI Std. 239-1 8 298-102 Mobility Networks Logistics Alisan Oztiirk HELMUT SCHMIDT UNIVERSITAT Universitat...Bahn AG, als Teil der DB Mobility Logistics AG, entstanden. Ziel dieser Arbeit ist es, ein Tool zur Umlaufplanung bei der DB zu verbes- sern. Dazu wird...vorgestellt. Dort geht es urn den Transport von Fahrzeugen zu Handlern uber Drittan- biet er , sogenannte 3PL . Dabei soll die Summe der

  9. Efficacy of mupirocin nasal ointment in eradicating Staphylococcus aureus nasal carriage in chronic haemodialysis patients

    NARCIS (Netherlands)

    D. L. Holton; L. E. Nicolle; D. Diley; K. Bernstein

    1991-01-01

    textabstractTopical 2% mupirocin ointment eradicated chronic Staphylococcus aureus nasal carriage immediately post-therapy in 17 (77%) of 22 haemodialysis patients. Mean time to recurrence was 3.8 weeks. Similar pre-therapy and post-therapy phage types occurred in 12 (71%) of 17 patients. Staphyloco

  10. Epidemiology and burden of nasal congestion

    Directory of Open Access Journals (Sweden)

    Michael Stewart

    2010-02-01

    Full Text Available Michael Stewart1, BJ Ferguson2, Len Fromer31Department of Otorhinolaryngology, Weill Cornell Medical College, New York-Presbyterian Hospital/Weill Cornell Medical Center, USA; 2Department of Otolaryngology, University of Pittsburgh School of Medicine, USA; 3University of California, Los Angeles; David Geffen School of Medicine Los Angeles, California, USAAbstract: Nasal congestion, which may be described as fullness, obstruction, reduced airflow, or being “stuffed up,” is a commonly encountered symptom in clinical practice. Systematic study of congestion has largely considered it as a component of a disease state. Conditions associated with congestion include nasal polyposis, obstructive sleep apnea, and anatomic variation; however, most information on the burden of congestion comes from studies of allergic rhinitis and rhinosinusitis, diseases of which congestion is the major symptom. Congestion can be caused by other rhinologic conditions, such as non-allergic rhinitis, viral or bacterial rhinitis, and vasomotor rhinitis. Allergic rhinitis affects as much as one quarter of the population worldwide and imposes a significant economic burden. Additionally, allergic rhinitis significantly impairs quality of life; congestion causes allergic rhinitis sufferers decreased daytime productivity at work or school and reduces night-time sleep time and quality. Annually, rhinosinusitis affects tens of millions of Americans and leads to approximately $6 billion in overall health care expenditures; it has been found to be one of the most costly physical conditions for US employers. Given the high prevalence and significant social and economic burden of nasal congestion, this symptom should be a key consideration in treating patients with rhinologic disease, and there continues to be a significant unmet medical need for effective treatment options for this condition.Keywords: allergic rhinitis, congestion, epidemiology, obstruction, rhinosinusitis

  11. Finite Element Model and Validation of Nasal Tip Deformation.

    Science.gov (United States)

    Manuel, Cyrus T; Harb, Rani; Badran, Alan; Ho, David; Wong, Brian J F

    2017-03-01

    Nasal tip mechanical stability is important for functional and cosmetic nasal airway surgery. Palpation of the nasal tip provides information on tip strength to the surgeon, though it is a purely subjective assessment. Providing a means to simulate nasal tip deformation with a validated model can offer a more objective approach in understanding the mechanics and nuances of the nasal tip support and eventual nasal mechanics as a whole. Herein we present validation of a finite element (FE) model of the nose using physical measurements recorded using an ABS plastic-silicone nasal phantom. Three-dimensional photogrammetry was used to capture the geometry of the phantom at rest and while under steady state load. The silicone used to make the phantom was mechanically tested and characterized using a linear elastic constitutive model. Surface point clouds of the silicone and FE model were compared for both the loaded and unloaded state. The average Hausdorff distance between actual measurements and FE simulations across the nose were 0.39 ± 1.04 mm and deviated up to 2 mm at the outermost boundaries of the model. FE simulation and measurements were in near complete agreement in the immediate vicinity of the nasal tip with millimeter accuracy. We have demonstrated validation of a two-component nasal FE model, which could be used to model more complex modes of deformation where direct measurement may be challenging. This is the first step in developing a nasal model to simulate nasal mechanics and ultimately the interaction between geometry and airflow.

  12. Nasal mites of Tyrannidae (Aves in Brazil

    Directory of Open Access Journals (Sweden)

    MM. Mendes

    Full Text Available A total of 81 Tyraniidae birds were examined, 80 Pitangus sulphuratus (Linnaeus, 1766 (Great kiscadee, and one Machetornis rixosa (Vieilot, 1819 (Cattle tyrant, for collection of nasal mites, which were identified as Ptilonyssus spinosus (Brooks & Strandtmann, 1960 and Sternostoma longisetosae (Hyland, 1961 (Rhinonyssidae. This finding characterises the first report of P. spinosus and S. longisetosae in P. sulphuratus, and the first record of P. spinosus in M. rixosa, and expands the geographic distribution of these species. It is the first occurrence of S. longisetosae in the Neotropics, and the first citation of P. spinosus in the state of Rio Grande do Sul, Brazil.

  13. Septum nasal perforation: treatments and literature' review

    Directory of Open Access Journals (Sweden)

    Martinez Neto, Eulógio Emílio

    2010-03-01

    Full Text Available Introduction: The present study consists in a bibliographical' review concerning the articles related to the different manifestations and forms of the septum nasal perforation, with a main emphasis in the description of its techniques of surgical correction. As the etiology, that is fundamentally iatrogenic, accordingly surgical trauma. Other causes include exhibition to chemical industrial reagents, cocaine use, intranasal steroidal therapeutic, neoplasia and, infectious conditions. There is a few data concerning the prevalence of septum perforation in the general population. The decision making about surgical correction or medical treatment depend on the anatomic characteristics and of the pathogenesis of the septal perforation.

  14. Fronto-nasal Encephalocele. A Case Report

    Directory of Open Access Journals (Sweden)

    Rafael Ferrer Montoya

    2013-06-01

    Full Text Available Encephalocele is a herniation of the brain tissue through a congenital or acquired defect of the skull. The congenital condition is caused by a neural-tube defect attributable to an interaction among several genes and environmental factors. Anterior encephalocele is a rare entity and its incidence varies depending on the geographic area. We report the case of a newborn with a tumour protruding through the fronto-nasal region with a central pedunculated polypoid formation, in addition to the presence of bilateral cleft lip and palate. Surgical treatment was decided after consulting the Neurosurgery Department. This case report is interesting due to the rarity of this entity.

  15. Chronic urticaria treated with soft nasal filters

    Directory of Open Access Journals (Sweden)

    Pasricha J

    1995-01-01

    Full Text Available A 22-year-old boy having two attacks of urticaria per day for the last 5 years and intermittent attacks of sneezing and rhinorrhoea, and without any clues to the causative agent in spite of a detailed history and follow up, showed almost complete relief on wearing an ordinary cloth mask for 3 days. He was subsequently trained to use the soft nasal filters and obtained almost 80% relief in urticaria and complete relief in rhinitis during the next 1 year. Wearing the mask for 2 days again led to complete relief and further training in the proper use of the filters was helpful.

  16. Die Verteilung und Eigenschaften von Bodenformen in der Deutschen Bucht, eine Rekonstruktion der Karten von Ulrich (1973)

    DEFF Research Database (Denmark)

    Winter, Christian; Lefebvre, Alice; Benninghoff, Markus

    2015-01-01

    Entstehung, Gestalt und Dynamik von Bodenformen in vergleichsweise kleinen Untersuchungsgebieten ist die Arbeit von ULRICH (1973) über die Verteilung von Bodenformen in der Deutschen Bucht bis heute die einzige verfügbare zusammenhängende Darstellung für die deutsche Nordseeküste. Die analogen Karten und die...

  17. Herstellung von Bio-Fleisch- und Wurstwaren ohne Einsatz von Pökelstoffen

    OpenAIRE

    2008-01-01

    Bei der ökologischen Herstellung von Fleisch- und Wurstwaren werden vielfach auf die in der konventionellen Wurstherstellung verwendeten Konservierungsstoffe E 250 (Natriumnitrit) bzw. E 252 (Kaliumnitrat) verzichtet oder reduzierte Zugabemengen der Zusatzstoffe verwendet.

  18. Der Briefwechsel zwischen Alexander von Humboldt und Karl Ernst von Baer

    Directory of Open Access Journals (Sweden)

    Thomas Schmuck

    2012-10-01

    Full Text Available Zusammenfassung Der kurze, nicht vollständig erhaltene Briefwechsel zwischen Alexander von Humboldt und Karl Ernst von Baer behandelt sehr verschiedene Themen: Politik, Kriegsgefahr, den Wissenschaftsbetrieb, Auszeichnungen und Tagungen, Embryologie und Cholera. Gemeinsam mit Briefen und Reden ergibt sich dabei ein differenziertes Bild der Beurteilung der beiden Wissenschaftler durch den jeweils anderen. Während Baer sich als Bewunderer Humboldts erweist, erscheint umgekehrt Humboldts Einschätzung Baers als ambivalent. Abstract The short, not completely preserved correspondence between Alexander von Humboldt and Karl Ernst von Baer deals with a wide range of subjects: politics and the danger of war, academic activities, scientific awards and conferences, aspects of embryology and the cholera. Letters to third persons and speeches, together with the correspondence between Humboldt and Baer show a differentiated pattern of mutual appraisal: While Baer always remained an admirer of the elder naturalist, Humboldt’s estimation was characterized by ambivalence.

  19. Von der Medienwirkungsbehauptung zur erziehungswissenschaftlichen Medienrezeptionsforschung. Vorschlag zur Analyse von Filmkommunikaten

    Directory of Open Access Journals (Sweden)

    Barbara Drinck

    2001-04-01

    Full Text Available Im Hinblick auf die Erforschung spezifischer Zusammenhänge von Medienkonsum und der Herausbildung von Einstellungen und Handlungen wird eine konstruktivistische Theorieorientierung plausibilisiert, indem zunächst auf den Stand der Medienwirkungsforschung eingegangen und vor dem Hintergrund einer begründeten Kritik des Wirkungsverständnisses auf die Notwendigkeit einer medienrezeptionswissenschaftlichen Forschungsalternative hingewiesen wird. Weiterhin wird der Stand der (erziehungswissenschaftlichen Medienrezeptionsforschung erörtert. Sodann werden Elemente einer konstruktivistischen Methodologie von Medienrezeptionsforschung beschrieben, die am Beispiel der Rezeption von Filmen konkretisiert werden. Dabei wird das Konzept des Kommunikates (S.J. Schmidt als Ausgangspunkt genommen, ein Vorschlag für eine Beschreibungssprache für (Film- Kommunikate entwickelt und eine Adaption des Ansatzes filmischer Narration zur Sprache gebracht.

  20. Auswirkung von Umweltchemikalien auf die Biologie von Chironomiden und Fischen als deren Prädatoren

    OpenAIRE

    Langer-Jaesrich, Miriam

    2012-01-01

    Im Rahmen der Dissertation wurden in mehreren Teilprojekten die Auswirkungen von Umweltchemikalien auf Chironomiden als Schlüsselorganismen in aquatisch-benthischen Lebensräumen untersucht. Dabei lag der Fokus besonders auf der Erfassung von nicht-standardisierten Endpunkten und Bioindikatoren sowie auf der Bearbeitung einer weiterführenden ökologisch relevanten Fragestellung zum Räuber-Beute-Verhältnis unter Schadstoffeinfluss. Im ersten Teil der Dissertation wurde das herkömmliche Standa...

  1. Synthese von grenzflächenaktiven Monomeren zur Herstellung von funktionalen Metall-Chalkogenid/Polymer-Hybridnanopartikeln

    OpenAIRE

    Fischer, V.

    2013-01-01

    In dieser Arbeit wurde gezeigt, wie oberflächenfunktionalisierte Polystyrolnanopartikel zur Herstellung von Metallchalkogenid/Polymer-Hybridnanopartikeln eingesetzt werden können. Dazu wurden zunächst phosphonsäure- und phosphorsäurefunktionalisierte Surfmere synthetisiert, die anschließend bei der Miniemulsionspolymerisation von Styrol verwendet wurden. Die Surfmere dienten dabei zugleich zur Stabilisierung und als Comonomer. Die oberflächenfunktionalisierten Polystyrolnanopartikel wurden an...

  2. Untersuchung der Rolle von Rhodopsin 7 und Cryptochrom im Sehprozess von Drosophila melanogaster

    OpenAIRE

    Grebler, Rudi

    2015-01-01

    Ausgangspunkt für die Detektion von Licht ist im gesamten Tierreich die Absorption von Photonen durch photorezeptive Proteine, die sogenannten Opsine und in geringerem Ausmaß die Typ 1 Cryptochrome. Die Taufliege Drosophila melanogaster besitzt sechs eingehend charakterisierte, auch als Rhodopsine bezeichnete Opsine (Rh1-Rh6) und ein Cryptochrom (CRY). Neben den Ocellen und den Hofbauer-Buchner Äuglein werden die Rhodopsine in erster Linie in den Photorezeptorzellen der Komplexaugen, den Haup...

  3. Untersuchungen zur Trockenentschwefelung von Brenngasen durch Partialoxidation von H2S an Herdofenkoks

    OpenAIRE

    Bauersfeld, Dirk

    2009-01-01

    Die vorliegende Arbeit befasst sich mit Untersuchungen zur Trockenentschwefelung von Brenngasen durch Partialoxidation von H2S an Herdofenkoks. Hierzu wurden Versuche in der Technikumsanlage VTE 2004 mit einem simulierten PHTW Gas durchgeführt. Es zeigte sich, dass der COS-Abbau nicht wie bisher angenommen durch die COS-Partialoxidation sondern durch die COS-Hydrolyse erfolgt. Die COS-Hydrolyse gewinnt dabei mit abnehmender Raumbelastung an Bedeutung. Der Entschwefelungsgrad erhöht sich mit s...

  4. Dentinhaftung von Zementen. Der Haftverbund von Zementen mit Dentin in Kombination mit verschiedenen indirekten Restaurationsmaterialien

    OpenAIRE

    Peutzfeldt, Anne; Sahafi, Alireza; Flury, Simon

    2011-01-01

    Einleitung: Die Anzahl zahnärztlicher Zemente sowie Restaurationsmaterialien steigt stetig. Die richtige Zementwahl für einen zuverlässigen Haftverbund zwischen Restaurationsmaterial und Zahnsubstanz ist von Interesse für den Kliniker. Ziel der vorliegenden in vitro-Studie war es daher, den Dentinhaftverbund von verschiedenen Zementen in Kombination mit verschiedenen indirekten Restaurationsmaterialien zu untersuchen. Material und Methoden: Zylindrische Probekörper aus sechs Restaurations...

  5. Substitution of R502 in existing refrigerating, air-conditioning and heat pump systems with refrigerants of low ozone depletion potential in the Federal Republic of Germany; Ersatz von R 502 in bestehenden Kaelte-, Klima- und Waermepumpenanlagen in der Bundesrepublik Deutschland durch Kaeltemittel mit geringerem Ozonabbaupotential

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1997-06-01

    The technical basics and the state of engineering for the substitution of R502 in existing refrigeration systems are described and explained. The report contains an overview of the current applications of R502 in the FRG, the presentation and discussion of existing substitutes, the presentation and valuations of research and experiences with the adaptation to alternative refrigerants, the presentation of the required infrastructure and a discussion of the technical feasibility. The conversion of existing systems to refrigerants of lower ozone depletion potential is in conclusion valuated with regard to its technical feasibility, environmental relevance and economic efficiency. (orig.) [Deutsch] Es werden die technischen Grundlagen und der Stand der Technik zum Ersatz von R502 in bestehenden Kaelteanlagen dargestellt und erlaeutert. Der Bericht beinhaltet einen Ueberblick ueber die derzeitige Anwendung von R502 in der BRD, die Vorstellung und Diskussion existierender Ersatzstoffe, die Darstellung und Bewertung der Forschung und Erfahrungen zu Umruestungen auf Ersatzstoffe, die Vorstellung der erforderlichen Infrastruktur und die Diskussion der technischen Durchfuehrbarkeit. Die Umstellung bestehender Anlagen auf Kaeltemittel mit geringerem Ozonabbaupotential wird abschliessend hinsichtlich der technischen Durchfuehrbarkeit, der Umweltrelevanz und der Wirtschaftlichkeit bewertet. (orig.)

  6. Substitution of R502 in existing refrigerating, air-conditioning and heat pump systems with refrigerants of low ozone depletion potential in the Federal Republic of Germany; Ersatz von R 502 in bestehenden Kaelte-, Klima- und Waermepumpenanlagen in der Bundesrepublik Deutschland durch Kaeltemittel mit geringerem Ozonabbaupotential

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1997-06-01

    The technical basics and the state of engineering for the substitution of R502 in existing refrigeration systems are described and explained. The report contains an overview of the current applications of R502 in the FRG, the presentation and discussion of existing substitutes, the presentation and valuations of research and experiences with the adaptation to alternative refrigerants, the presentation of the required infrastructure and a discussion of the technical feasibility. The conversion of existing systems to refrigerants of lower ozone depletion potential is in conclusion valuated with regard to its technical feasibility, environmental relevance and economic efficiency. (orig.) [Deutsch] Es werden die technischen Grundlagen und der Stand der Technik zum Ersatz von R502 in bestehenden Kaelteanlagen dargestellt und erlaeutert. Der Bericht beinhaltet einen Ueberblick ueber die derzeitige Anwendung von R502 in der BRD, die Vorstellung und Diskussion existierender Ersatzstoffe, die Darstellung und Bewertung der Forschung und Erfahrungen zu Umruestungen auf Ersatzstoffe, die Vorstellung der erforderlichen Infrastruktur und die Diskussion der technischen Durchfuehrbarkeit. Die Umstellung bestehender Anlagen auf Kaeltemittel mit geringerem Ozonabbaupotential wird abschliessend hinsichtlich der technischen Durchfuehrbarkeit, der Umweltrelevanz und der Wirtschaftlichkeit bewertet. (orig.)

  7. [The Costantin Von Economo's lethargic encefalitis

    Science.gov (United States)

    Pistacchio, E.

    1998-01-01

    Starting from the Constantin Von Economo's description of a "new" disease, the lethargic encephalitis, the author delineates the history of an infectious sleeping sickness that caused epidemics in Europe from 1917 to 1928 and led to create, in Italy, the "Institutes for Encephalitis".

  8. Die larvale Entwicklung von Chirocentrus dorab (Forsk.)

    NARCIS (Netherlands)

    Delsman, H.C.

    1922-01-01

    Wer sich mit dem Studium der Lebensweise indischer Fische befassen will, hat dabei den grossen Vorteil, sich beim Bestimmen der Species auf die zahlreichen Arbeiten BLEEKER’S stützen zu können, während ihm das Determinieren ganz besonders erleichtert wird durch das von dichotomischen Tabellen

  9. Soolopartiid Von Krahli katuse all / Kristi Eberhart

    Index Scriptorium Estoniae

    Eberhart, Kristi

    2007-01-01

    Von Krahli Teatri kolmest lavastusest: "Erki ja Tiina" (lavastaja Mart Kangro, tantsivad Erki Laur ja Tiina Tauraite), "Faust" (J. W. Goethe ainetel tekst ja lavastus Taavi Eelmaa, muusika ja laulud Chalice, osades Jarek Kasar ja Rein Pakk), "Hamletid" (William Shakespeare'i ainetel kontseptsiooni, lavastuse, koreograafia, kujunduse, valguse autor Sasha Pepeljajev, video- ja helikunstnik Taavet Jansen. Esitaja Juhan Ulfsak)

  10. Drei neue Chelonarium-Arten von Sumatra

    NARCIS (Netherlands)

    Reitter, Edm.

    1886-01-01

    Die Arten dieser Gattung kommen vorherschend in Central- und Süd-Amerika vor, doch sind in neuerer Zeit auch drei Arten: Ch. orientale Reitt. 1), conspersum Reitt. 2) und adspersum Chevrl.3) von den grossen Sunda-Inseln und Malakka bekannt geworden, zu denen nun weitere 3 Arten treten, die ich nachf

  11. Ueber eine Anomalie von Acromitus flagellatus (Stiasny)

    NARCIS (Netherlands)

    Stiasny, G.

    1934-01-01

    Bei erneuter Durchsicht des reichhaltigen Materiales von Acromitus flagellatus (Stiasny) in der Scyphomedusen-Sammlung des Rijksmuseum van Natuurlijke Historie in Leiden (vergl. meine Mitteilungen daruber, 1920, Uebersichtstabelle III und 1921, p. 131/136) fand ich ein Exemplar, das eine

  12. Ueber zwei neue Vogelarten von Java

    NARCIS (Netherlands)

    Finsch, O.

    1902-01-01

    Die beiden nachstehend beschriebenen Vögel wurden mir von Herrn Max Bartels als muthmasslich neu zugesandt. Die genaue Untersuchung hat dies bestätigt. Ich freue mich daher eine der Arten zu Ehren des Entdeckers benennen zu können. Seit einigen Jahren als Leiter der Plantage Pangerango bei Pasir Dat

  13. Active Von Willebrand Factor, thrombocytopenia and thrombosis

    NARCIS (Netherlands)

    Hulstein, J.J.J.

    2006-01-01

    Platelets and von Willebrand factor (VWF) are unable to interact in circulation. To induce an interaction, a conversion of VWF to a platelet-binding conformation is required. At higher shear stresses, the first step in thrombus formation is binding of VWF to the subendothelium. This results in expos

  14. The von Bertalanffy growth model for horticulture

    NARCIS (Netherlands)

    Tijskens, L.M.M.; Schouten, R.E.; Unuk, T.; Šumak, D.

    2017-01-01

    Traditionally, crop load and fruit yield from previous seasons are used as indicators for prediction of fruit size. Disregarding the inevitable biological variation between fruit, von Bertalanffy (1938) described the growth, expressed as length, of virtually any living organism. The model is here

  15. Von Kalifornien nach Taxham / Katri Soe

    Index Scriptorium Estoniae

    Soe, Katri, 1971-

    2005-01-01

    Neljas osa magistritööst "Von Kalifornien nach Taxham: Formen und Strukturen der Kommunikation in Peter Handkes Romanen "Der kurze Brief zum langen Abschied" und "In einer dunklen Nacht ging ich aus meinem stillen Haus"" (Tartu, 2000. Juhendaja: Claus Sommerhage)

  16. Ueber eine Anomalie von Acromitus flagellatus (Stiasny)

    NARCIS (Netherlands)

    Stiasny, G.

    1934-01-01

    Bei erneuter Durchsicht des reichhaltigen Materiales von Acromitus flagellatus (Stiasny) in der Scyphomedusen-Sammlung des Rijksmuseum van Natuurlijke Historie in Leiden (vergl. meine Mitteilungen daruber, 1920, Uebersichtstabelle III und 1921, p. 131/136) fand ich ein Exemplar, das eine bemerkenswe

  17. Zustandsschätzung von aktiven Fahrwerkregelsystemen

    NARCIS (Netherlands)

    Leenen, R.; Maurice, J.P.

    2010-01-01

    Eine Weiterentwicklung von Fahrdynamikregelung, Überroll- und Seitenaufprallschutz sowie Pre-Crash-Funktionen und Kollisionsminderung verspricht TNO. Mit einem System zur Beobachtung des aktuellen Fahrzeugzustands (Vehicle State Estimator – VSE) bietet der niederländische Zulieferer ein zentrales Mo

  18. Ueberreste vorweltlicher Proboscidier von Java und Banka

    NARCIS (Netherlands)

    Martin, K.

    1884-01-01

    Junghuhn führte in seinem Werke über Java nur einen einzigen Wirbelthierrest, Carcharias megalodon, an (7, IV, pag. 97); es war ihm nicht gelungen bei seinem ersten Aufenthalte auf der Insel Reste von Säugethieren zu finden, so eifrig er auch darnach in den Höhlen des Tertiaergebirges suchte (7, IV,

  19. Entendendo a entropia de von Neumann

    OpenAIRE

    Maziero, Jonas

    2015-01-01

    Revisamos os postulados da mecânica quântica necessários para discutir a entropia de von Neumann, que é introduzida como uma generalização da entropia de Shannon e propomos um jogo simples que facilita o entendimento do seu significado físico.

  20. Das Haarkleid eines Fetus von Schimpanse

    NARCIS (Netherlands)

    Bolk, L.

    1919-01-01

    In seiner ausführlichen Arbeit über die Richtung der Haare bei den Affenembryonen nebst allgemeinen Erörterungen über die Ursachen der Haarrichtungen, hat Schwalbe eine Fülle von Tatsachen und eine wertvolle kritische Betrachtung über das Problem der Haarrichtungen geliefert. Leider war der Autor ni

  1. The Efficacy of a Protocolized Nursing Care on Nasal Skin Breakdown in Preterm Neonates Receiving Nasal Continuous Positive Airway Pressure

    Directory of Open Access Journals (Sweden)

    Mahnaz Jabraeili

    2017-01-01

    Full Text Available Background: Nasal continuous positive airway pressure (NCPAP is an effective method of ventilation in newborns with respiratory distress syndrome (RDS. Using an appropriate nasal skin care protocol is identical to prevention or reduction of nasal skin breakdown in those who receive NCPAP. This study aimed to investigate the effectiveness of an evidence-based clinical care protocol on nasal skin integrity in preterm newborns who receive NCPAP.Materials and Methods: A Randomized Controlled Trial was used to conduct the study. A cohort of 110 preterm newborns with a gestational age (GA of 25 to 36 weeks, receiving nasal continuous positive airway pressure (NCPAP for RDS in the neonatal intensive care unit of a university teaching hospital were selected to perform the study. They were randomly assigned to a protocolized nasal skin care (group A or to a group receiving the routine care (group B. Nasal skin integrity of the preterm neonates, were measured on a daily basis for 10 days using the Neonatal Skin Condition Scale (NSCS 24 hours after placement of NCPAPs in both groups.Results: Each intervention and control group included 55 neonates. 65.50% of neonates in the control group and 47.30% of neonates in the intervention group were male. Repeated measures analysis showed thatNSCS scores were significantly lower in intervention group receiving nasal skin care in accordance with the protocol than the control group receiving the routine nasal skin care (P=0.000. Conclusion: In this study, the protocolized care reduced nasal skin breakdown in the preterm newborns receiving NCPAP. Therefore, it can be used as an effective method in nasal skin care in neonates who are treated by NCPAP.

  2. Langerhans cells and subsets of lymphocytes in the nasal mucosa

    DEFF Research Database (Denmark)

    Hellquist-Dahl, B; Olsen, K E; Irander, K;

    1991-01-01

    Langerhans cells and different lymphocytes were studied in the nasal mucosa of 39 woodwork teachers and a control group of 14 healthy subjects. Ten of the woodwork teachers were sensitized as determined by skin prick test. A panel of different monoclonal antibodies was applied on the frozen nasal...

  3. Polyvinyl siloxane: novel material for external nasal splinting.

    Science.gov (United States)

    Jayakumar, N K; Rathnaprabhu, V; Ramesh, S; Parameswaran, A

    2016-01-01

    External nasal splinting is performed routinely after nasal bone fracture reductions, osteotomies, and rhinoplasties. Materials commonly used include plaster of Paris (POP), thermoplastic splints, self-adhesive padded aluminium splints, and Orthoplast, among many others. The disadvantages of these materials are described in this paper, and polyvinyl siloxane is recommended as an effective and more readily available alternative material to counter these pitfalls.

  4. [Use of Solcoseryl DAP after nasal septum surgery].

    Science.gov (United States)

    Krzeski, A; Makowska, W

    1991-01-01

    Solcoseryl is a biological agent, which accelerates the healing tissue procedure. This influence was studied during the nasal septum surgery. In 25 patients the postoperational nasal plug was inserted with the Solcoseryl and in 10 (control) with the paraffin. The cytologic verifications were performed before and after the surgery. In the solcoseryl group the mucosa regeneration procedure was accelerated and the inflammation reduced.

  5. Nasal cytochrome P4502A: Identification in rats and humans

    Energy Technology Data Exchange (ETDEWEB)

    Thornton-Manning, J.R.; Hotchkiss, J.A. [Michigan State Univ., East Lansing, MI (United States); Ding, Xinxin [Wadsworth Center for Laboratories and Research, Albany, NY (United States)] [and others

    1995-12-01

    The nasal mucosa, the first tissue of contact for inhaled xenobiotics, possesses substantial enobiotic-metabolizing capacti. Enzymes of the nasal cavity may metabolize xenobiotics to innocuous, more water-soluble compounds that are eliminated from the body, or they may bioactivate them to toxic metabolites. These toxic metabolites may find to cellular macromolecules in the nasal cavity or be transported to other parts of the body where they may react. Nasal carcinogenesis in rodents often results from bioactivation of xenobiotics. The increased incidences of nasal tumors associated with certain occupations suggest that xenobiotic bioactivation may be important in human nasal cancer etiology, as well. The increasing popularity of the nose as a route of drug administration makes information concerning nasal drug metabolism and disposition vital to accomplish therapeutic goals. For these reasons, the study of xenobiotic-met abolizing capacity of the nasal cavity is an important area of health-related research. In the present study, we have confirmed the presence of CYP2A6 mRNA in human respiratory mucosa.

  6. Nasal endoscopy is recommended for diagnosing adults with chronic rhinosinusitis

    NARCIS (Netherlands)

    Wuister, A.M.H.; Goto, N.A.; Oostveen, E.J.; de Jong, W.U.; van der Valk, E.S.; Kaper, N.M.; Aarts, M.C.J.; Grolman, W.; van der Heijden, G.J.M.G.

    2014-01-01

    Objective To assess the diagnostic value of nasal endoscopic findings in adults suspected of chronic rhinosinusitis. Data Sources PubMed, EMBASE, and the Cochrane Library. Review Methods A comprehensive search was performed up to March 5, 2013. Articles that assessed the diagnostic value of nasal en

  7. Nasal air-conditioning after partial turbinectomy: myths versus facts.

    Science.gov (United States)

    Tsakiropoulou, Evangelia; Vital, Victor; Constantinidis, Jannis; Kekes, George

    2015-01-01

    Turbinectomy, although a common procedure, is often accused of having a negative impact in all nasal functions. This study is the first in vivo study that evaluates objectively the effect of partial turbinectomy on nasal air-conditioning capacity. In total, 57 patients with prior partial inferior turbinectomy and 28 healthy controls were examined. Intranasal temperature and humidity values were measured at the level of the head of inferior and middle turbinate. Nasal patency was evaluated by means of acoustic rhinometry. The clinical assessment was completed with nasal endoscopy and the Nasal Obstruction Symptom Evaluation questionnaire for subjective evaluation of nasal patency. Significant changes of temperature were found in both detection sites with 13% reduced heating capacity of the air at the level of the inferior and 19% at the level of the middle turbinate, respectively. No similar results were found for humidity measurements. No correlations were found between air-conditioning values and acoustic rhinometry results for both study groups. Nasal endoscopy revealed normal healing in all patients. No major complications were reported by the patients. Their subjective ratings of nasal obstruction were similar to healthy controls. Partial turbinectomy seems to have a negative impact on intranasal air heating but not to humidification. This effect has no impact on clinical condition and subjective perception of surgical outcome.

  8. Resident aerobic microbiota of the adult human nasal cavity

    DEFF Research Database (Denmark)

    Rasmussen, TT; Kirkeby Nielsen, LP; Poulsen, Knud

    2000-01-01

    Recent evidence strongly suggests that the microbiota of the nasal cavity plays a crucial role in determining the reaction patterns of the mucosal and systemic immune system. However, little is known about the normal microbiota of the nasal cavity. The purpose of this study was to determine the m...

  9. INTERESTING CASE RECORD OF A TOOTH INSIDE NASAL CAVITY

    Directory of Open Access Journals (Sweden)

    Balasubramanian Thiagarajan

    2011-09-01

    Full Text Available I am presenting an interesting case report of an ectopic eruption of teeth into left nasal cavity. Discussion is focused on clinical, radiological presentation, probable etiology, diagnosis, management and complications.Tooth inside nasal cavity is a rare form of supernumerary teeth which can be identified by performing CTscan.

  10. International Consensus on Nasal Polyposis 2002-2004.

    Science.gov (United States)

    Mladina, R; Clement, P; Lopatin, A; Mann, W; Passali, D

    2005-06-01

    Seventeen well-known experts in rhinosinusology from various countries tried to achieve consensus on the etiology, conservative approach and surgical approach to nasal polyposis. A Digi-Vote electronic system was used for an immediate computer analysis of expert answers to 23 questions related to the problem of nasal polyposis.

  11. Sinn und Möglichkeiten der Theoretischen Physik. Zum 300. Jahrestag von Newtons Philosophiae Naturalis Principia Mathematica

    Science.gov (United States)

    Rompe, R.; Thiessen, P. A.; Treder, H.-J.

    Die Newtonschen Prinzipien und die aus ihnen gewonnene Erkenntnis der Existenz von Elementarkonstanten nach Planck, Einstein und Bohr erweisen sich zunehmend als tragfähiges Fundament nicht nur der Physik und ihrer Anwendung in der Technik, sondern überhaupt aller exakten Wissenschaften in breitestem Sinne des Wortes.Die physikalisch inhaltliche Klärung der Begriffe erfolgt seit Newton in engem Verbund mit der Entwicklung mathematischer Methoden. Diese Kombination erweist sich weiterhin als produktiv und sichert den Fortschritt der Physik und der exakten Wissenschaften.Wohl alle Probleme, die im Bereich der Technik Bedeutung haben können, lassen sich bei entsprechendem Aufwand bereits mit dem vorhandenen Fundus an Erkenntnissen und Methoden erfolgreich angehen.Der in der Wirklichkeit verankerte Zusammenhang von Gesetz und Zufall erweist sich als eine Manifestation der Dialektik in der Natur. Es gibt keinen absoluten Zufall. Sie kommt in allen Zweigen der Physik, nicht nur in der Thermodynamik und Quantenphysik, zutage, und muß bereits auf dem Niveau der Newtonschen Prinzipien und der Elementarkonstanten behandelt werden.Die theoretische Physik, so wie sie von Newton initiiert worden ist, wurde so angelegt, daß sie alle Seiten der Wirklichkeit, so weit sie in die Kompetenz der Physik fallen, umfaßt. Es besteht darum kein Gegensatz zwischen der klassischen Physik und der Quantenphysik. Es handelt sich lediglich um eine Differenzierung nach den unterschiedlichen physikalischen Inhalten und den angemessenen mathematischen Methoden, die natürlich von der Wahl der Probleme abhängen.Die theoretische Physik stellt eine allgemein zugängliche Zusammenfassung des gesicherten Wissens der Physik dar, das zugleich das Fundament der exakten Wissenschaften ist.Die theoretische Physik ist damit das Mittel der Verständigung innerhalb der Kooperation, die notwendig ist zur Lösung der großen komplexen Aufgaben der Wissenschaft und Technik.Translated AbstractThe Meaning

  12. Persistent organic compounds in food chains in Bavaria and Czechia. Pt. 1. Terrestrial systems; Persistente organische Verbindungen in Nahrungsketten von Bayern und Tschechien. T. 1. Terrestrische Systeme

    Energy Technology Data Exchange (ETDEWEB)

    Kettrup, A.; Heinisch, E.

    1997-10-01

    , zusammengetragen und - soweit dies moeglich war - verglichen und gegenuebergestellt. Die Ergebnisse sind in Zusammenfassungen der Einzelkapitel aufgefuehrt. Es konnte in z.T. fundierten Ansaetzen gezeigt werden, dass die unterschiedlichen sozialoekonomischen Strukturen der Regionen bis 1989 erhebliche Einfluesse auf die Ausmasse der Kontamination ausuebten. Umfangreiche Gesetzeswerke zur Anwendung und Herstellung von Chemieprodukten und deren immer dichtere Ueberwachung in Bayern fuehrten ebenso wie zahlreiche Sanierungsmassnahmen dazu, dass die klassischen chlororganischen Verbindungen nur noch in Spuren vorkommen und auch unvermeidbare Verbindungen wie PCDD/F minimiert werden koennen. Diese Voraussetzungen wurden in den neuen Bundeslaendern - hier dargestellt am Beispiel Brandenburg - wo bis 1989 die Volkswirtschaft ausschliesslich auf Produktionsmaximierungen ausgerichtet war, geschaffen und beginnen sich in deutlichen Abnahmen der Kontaminationshoehen (fuer PCDD/F und PAK lagen keine Materialien vor) insbesondere fuer die klassischen CKW auszuwirken. In Tschechien werden immer noch erheblich hoehere Belastungen z.B. fuer HCB und vor allem PCB registriert, die ein Augenmerk auf moegliche grenzueberschreitende Wirkungen erforderlich machen. (orig.)

  13. Antibakterielle In-vitro-Wirksamkeit ätherischer Öle gegen veterinärmedizinisch relevante Keime klinischer Isolate von Hunden, Katzen und Pferden.

    Science.gov (United States)

    Bismarck, Doris; Schneider, Marianne; Müller, Elisabeth

    2017-01-01

    Einleitung: Ätherische Öle sind die Grundlage der Aromatherapie. Unter anderem wird ihnen eine antibakterielle Wirkung zugeschrieben. In dieser Studie sollte die In-vitro-Wirksamkeit ätherischer Öle gegen ein breites Spektrum veterinärmedizinisch relevanter Erreger getestet werden. Methoden: Die antibakterielle Aktivität von 16 ätherischen Ölen wurde mittels Agardiffusionstest bestimmt. Getestet wurden grampositive und gramnegative Erreger, die aus klinischen Isolaten von Hunden, Katzen und Pferden aus der veterinärmedizinischen Routinediagnostik stammten. Die Einteilung der Wirksamkeit in nicht, gering-, mittel- und hochgradig wirksam erfolgte anhand der Größe der Hemmhofradien des Bakterienwachstums. Ergebnisse: Generell zeigten sich sowohl grampositive als auch gramnegative Erreger empfindlich gegen einige der getesteten ätherischen Öle. Nicht nur gegen Staphylokokken, sondern auch gegen Methicillin-resistente Stämme der Staphylokokken wiesen die ätherischen Öle in vitro eine nicht zu vernachlässigende Wirkung auf. Pasteurella multocida stellte sich als eher sensibler Keim heraus, während Pseudomonas aeruginosa als vollkommen resistenter Keim eine Ausnahme bildete. Teebaum-, Oregano-, und Bergbohnenkrautöl waren die potentesten Öle. Zusätzlich zeigten sich bei den grampositiven Erregern Lemongrasöl und bei den gramnegativen Erregern Thymianöl als gut wirksam. Schlussfolgerung: Ätherische Öle verfügen in vitro über eine antibakterielle Aktivität gegen klinische Isolate von Hunden, Katzen und Pferden. Diese Studie bietet eine Grundlage für die Anwendung ätherischer Öle in der Veterinärmedizin. Es zeichneten sich Tendenzen im Wirkspektrum einzelner ätherischer Öle bzw. im Grad der Wirksamkeit ätherischer Öle hinsichtlich einzelner Erregerspezies ab, allerdings lässt sich keine sichere Vorhersage über ihre Wirksamkeit gegen einen spezifischen Keim eines individuellen Patienten treffen. Deswegen sollte vor einer Therapie mit

  14. The nasal distribution of metered dose inhalers.

    Science.gov (United States)

    Newman, S P; Morén, P F; Clarke, S W

    1987-02-01

    The intranasal distribution of aerosol from a metered dose inhaler has been assessed using a radiotracer technique. Inhalers were prepared by adding 99Tcm-labelled Teflon particles (simulating the drug particles) to chlorofluorocarbon propellants, and scans of the head (and chest) taken with a gamma camera. Ten healthy subjects (age range 19-29 years) each performed two radioaerosol studies with the inhaler held in two different ways: either in a single position (vial pointing upwards) or in two positions (vial pointing upwards and then tilted by 30 degrees in the sagittal plane). The vast majority of the dose (82.5 +/- 2.8 (mean +/- SEM) per cent and 80.7 +/- 3.1 per cent respectively for one-position and two-position studies) was deposited on a single localized area in the anterior one-third of the nose, the initial distribution pattern being identical for each study. No significant radioaerosol was detected in the lungs. Only 18.0 +/- 4.7 per cent and 15.4 +/- 4.1 per cent of the dose had been removed by mucociliary action after 30 minutes, and it is probable that the remainder had not penetrated initially beyond the vestibule. Since the deposition pattern was highly localized and more than half the dose probably failed to reach the turbinates it is possible that the overall effect of nasal MDIs is suboptimal for the treatment of generalized nasal disorders.

  15. A Case of Nasal Glial Heterotopia in an Adult

    Directory of Open Access Journals (Sweden)

    Akira Hagiwara

    2014-01-01

    Full Text Available We report a rare case of nasal glial heterotopia in an adult. After the surgery, frontal lobe cerebral hemorrhage developed. A 58-year-old man had unilateral nasal obstruction that progressed for one year. He had been treated for hypertension, chronic heart failure, and cerebral infarction with aspirin and warfarin. A computed tomography scan showed that the tumor occupied the right nasal cavity and the sinuses with small defect in the cribriform plate. The tumor was removed totally with endoscopy. After the operation, the patient developed convulsions and frontal lobe cerebral hemorrhage. The hemorrhage site was located near a defect in the cribriform plate. Nasal glial heterotopia is a rare developmental abnormality, particularly rare in adult. Only few cases were reported. We could not find any report of adult nasal glial heterotopias that developed cerebral hemorrhage as a complication of the surgery.

  16. A Nasalidade, um Velho Tema The nasality, an old theme

    Directory of Open Access Journals (Sweden)

    Leda BISOL

    1998-01-01

    Full Text Available O objetivo deste artigo é mostrar que o português possui dois processos de nasalização que, em níveis fonológicos separados, lexical e pós-lexical, originam, respectivamente, o ditongo e a vogal nasal. Na formação do ditongo, o efeito da estabilidade é o ponto essencial como é a assimilação para a vogal nasal.The aim of this paper is to show that Portuguese has two processes of nasalization, operantig in separate levels, the lexical one that originates the diphthong and the postlexical that originates the nasal vowel. In the formation of the diphthong, the stability effect, a local condition, is the fundamental point as the assimilation is, as spreading, for the nasal vowel.

  17. Handedness, eyedness and nasal cycle in children with autism.

    Science.gov (United States)

    Dane, Senol; Balci, Nese

    2007-06-01

    Autism is referred to as cerebral lateralization abnormality. In this study, the possible relationships among handedness, eyedness and nasal cycle in autism have been investigated. Thirty-seven children with autism and 20 controls were included in the study. The patient group included 27 boys and 10 girls who ranged in age from 5 to 20 years. For hand preference, hand used to write and throw a ball was accepted as dominant hand. For eye preference or dominance, eye used to look through keyhole of a door was accepted as dominant eye. Nasal dominance was assessed by a method of measuring the nasal airflow. The rates of left-handedness and left-eyedness were higher in children with autism compared to normal populations. A majority of children with autism had left nasal dominance. Autism and early language impairment may be associated with left handedness, eyedness and nasal dominance.

  18. Clinical evaluation of 30 patients with localized nasal rosacea.

    Science.gov (United States)

    Lee, Woo Jin; Lee, Ye Jin; Won, Chong Hyun; Chang, Sung Eun; Choi, Jee Ho; Lee, Mi Woo

    2016-02-01

    The clinical features of localized nasal rosacea have not been described in detail. This study was designed to analyze the subtypes and severity of localized nasal rosacea. Our present study included 30 patients with localized nasal rosacea. The erythematotelangiectatic subtype (13/30, 43.3%) was the most common type, followed by the phymatous subtype (9/30, 30%). The duration of rosacea was shorter and the severity of localized nasal rosacea was lower in the erythematotelangiectatic subtype cases compared with the patients with mixed or phymatous subtypes. Almost all of the papulopustular eruptions or phymatous lesions were associated with erythematotelangiectatic lesions. These findings suggest that the erythematotelangiectatic subtype may be considered the initial phase of localized nasal rosacea.

  19. Nasal allergies hayfever among young adults in Melbourne, Australia

    Directory of Open Access Journals (Sweden)

    Michael Abramson

    1997-01-01

    Full Text Available Although there is wide variation in the prevalence of nasal allergies internationally, the extent to which this is due to variation in etiological factors is not known. The purpose of the present study was to define the relative importance of atopy and other risk factors for nasal allergies, including hayfever, among young adults in Melbourne. The subjects were participants in the second phase of the European Community Respiratory Health Survey; 876 adults between 20 and 45 years of age completed a detailed respiratory questionnaire, 745 had skin prick testing with common aeroallergens and 675 underwent methacholine challenge. Total and allergen-specific IgE levels were measured in 701 and 693 subjects by radioimmunoassay and RAST, respectively. Nasal allergies, including hayfever, were reported by 47.5% of randomly selected participants. Females, non- smokers, subjects with a family history of allergies, those with current asthma, a history of eczema and nasal symptoms induced by dust, pollen or food were significantly more likely to have nasal allergies. Oral antihistamines had been used by 45.7% of those reporting nasal allergies and 12.4% had received allergen immunotherapy. The risk of nasal allergies, including hayfever, was increased 6.1-fold by atopy, particularly by positive skin tests to outdoor allergens such as Birch, Timothy grass, plantain, olive, Cladosporium and Rye grass pollen. Total serum IgE was significantly higher in subjects reporting nasal allergies than in those who did not report such allergies. There were significant trends in the prevalence of nasal allergies with increasing titers of specific IgE directed against all allergens tested. In conclusion, the significant independent risk factors for nasal allergies, including hayfever, in young adults were atopy, particularly sensitization to Timothy grass, house dust mites and plantain, current asthma, not smoking, a history of eczema and female gender. Future research

  20. Seasonal changes in nasal cytology in mite-allergic patients

    Directory of Open Access Journals (Sweden)

    Gelardi M

    2014-03-01

    Full Text Available Matteo Gelardi,1 Diego G Peroni,2 Cristoforo Incorvaia,3 Nicola Quaranta,1 Concetta De Luca,1 Salvatore Barberi,4 Ilaria Dell'Albani,5 Massimo Landi,6 Franco Frati,5 Olivier de Beaumont7 1Otolaryngology Unit, Department of Neuroscience and Sensory Organs, University of Bari, Bari, Italy; 2Department of Pediatrics, University of Verona, Verona, Italy; 3Allergy/Pulmonary Rehabilitation, ICP Hospital, Milan, Italy; 4Department of Pediatrics, San Paolo Hospital, Milan, Italy; 5Medical and Scientific Department, Stallergenes, Milan, Italy; 6Department of Pediatrics, National Healthcare System, ASL TO1, Turin, Italy; 7Medical Affairs Department, Stallergenes, Antony, France Background: House dust mites (HDMs are a major cause of allergic rhinitis (AR and asthma worldwide. Recent studies suggested that the allergen load presents seasonal modifications, giving rise to seasonal variation in nasal inflammation and symptoms. The aim of this study was to evaluate by nasal cytology whether nasal inflammation in mite-allergic patients changes with the seasons of the year. Methods: The study included 16 patients (seven males and nine females, mean age 38.1 years with persistent AR caused by monosensitization to HDMs. Nasal cytology was performed in all patients once monthly for 1 year. Results: Nasal cytology showed that the cells most commonly detected in the nasal mucosa were neutrophils. During the period from October to April, a peak in the number of neutrophils and also the presence of significant numbers of eosinophils, mast cells, and lymphocytes/plasma cells were found, which shows the occurrence of more intense inflammation during these months. Conclusion: Nasal cytology provides useful data in detecting nasal inflammation and its association with the clinical stage of AR. The seasonal variations in nasal cytology are likely to be induced by the fluctuations in the HDM allergen that have been uncovered in recent investigations. Keywords: allergens

  1. Nasal packing in sphenopalatine artery bleeding: therapeutic or harmful?

    Science.gov (United States)

    Sireci, F; Speciale, R; Sorrentino, R; Turri-Zanoni, M; Nicolotti, M; Canevari, F R

    2017-03-01

    The aim of this study is to present our management protocol of sphenopalatine artery bleeding, demonstrating that nasoendoscopic cautery (NC) was a more effective method than the nasal packing, in terms of shorter inpatient stay and reduced complications rate. We present ten posterior epistaxis not resolved by nasal packing. Tabotamp(®) was placed in the area of sphenopalatine foramen and/or in those parts of the posterior nasal cavity, where it was suspected that bleeding origins. In two cases, the bleeding was resolved in this way, instead eight cases needed of subperiosteal cauterization of sphenopalatine artery by Dessi bipolar forceps (MicroFrance(®)). 4 of these 8 patients evidenced a remarkable bleeding removing nasal packing (Hb before-nasal packing = 15 ± 0.69 versus Hb after-nasal packing = 13.3 ± 0.81; t student = 2.94; p value = 0.025). These four patients showed a deviation of the nasal septum ipsilateral to epistaxis, and according our experience, a traumatism of sphenopalatine area can be caused by Merocel(®) nasal packing in this condition. During follow-up, no recurrences of nasal bleeding have been observed in such patients. Nasal packing must be considered if posterior epistaxis is severe, but always taking into account the specific anatomy of patient and in particular septal spurs that can further compromise sphenopalatine artery. In our experience, the endoscopic endonasal cauterization of the sphenopalatine branches represented a safe and effective procedure.

  2. Effects of nasal drug delivery device and its orientation on sprayed particle deposition in a realistic human nasal cavity.

    Science.gov (United States)

    Tong, Xuwen; Dong, Jingliang; Shang, Yidan; Inthavong, Kiao; Tu, Jiyuan

    2016-10-01

    In this study, the effects of nasal drug delivery device and the spray nozzle orientation on sprayed droplets deposition in a realistic human nasal cavity were numerically studied. Prior to performing the numerical investigation, an in-house designed automated actuation system representing mean adults actuation force was developed to produce realistic spray plume. Then, the spray plume development was filmed by high speed photography system, and spray characteristics such as spray cone angle, break-up length, and average droplet velocity were obtained through off-line image analysis. Continuing studies utilizing those experimental data as boundary conditions were applied in the following numerical spray simulations using a commercially available nasal spray device, which was inserted into a realistic adult nasal passage with external facial features. Through varying the particle releasing direction, the deposition fractions of selected particle sizes on the main nasal passage for targeted drug delivery were compared. The results demonstrated that the middle spray direction showed superior spray efficiency compared with upper or lower directions, and the 10µm agents were the most suitable particle size as the majority of sprayed agents can be delivered to the targeted area, the main passage. This study elaborates a comprehensive approach to better understand nasal spray mechanism and evaluate its performance for existing nasal delivery practices. Results of this study can assist the pharmaceutical industry to improve the current design of nasal drug delivery device and ultimately benefit more patients through optimized medications delivery. Copyright © 2016 Elsevier Ltd. All rights reserved.

  3. In vitro tolerability of human nasal mucosa: histopathological and scanning electron-microscopic evaluation of nasal forms containing Sandostatin.

    Science.gov (United States)

    de Fraissinette, A; Kolopp, M; Schiller, I; Fricker, G; Gammert, C; Pospischil, A; Vonderscher, J; Richter, F

    1995-10-01

    An in vitro human nasal model was developed as a tool to study the local tolerability of nasal powder forms using excised nasal mucosa in a diffusion chamber. The suitability of this model was tested using Sandostatin (SMS) an octapeptide analog of somatostatin, as a reference drug enhanced by Avicel (microcrystalline cellulose) or lactose (100 mesh). The standard nasal spray vehicle was taken as a harmless control and 1% chenodeoxycholate (CDC) as a harmful control in terms of local tolerability. The extent of peptide permeation was determined by measuring SMS concentration in the receiving chamber. The labeling of SMS was detected by immunoperoxidase staining on cross sections. The local tolerability for all tested forms was assessed by histopathological examination and scanning electron microscopy. The apparent permeation coefficient allowed us to rank the absorption of the tested drug forms as Avicel > spray = lactose > 1%CDC. For all formulations, SMS was detected in the epithelium. No changes of the nasal mucosa could be observed with Avicel, lactose or nasal spray vehicle in the presence or absence of SMS. 1%CDC with or without drug showed an immediate destruction of the nasal epithelium. The validation of this in vitro model using human nasal mucosa will be further discussed as a tool for assessing the local tolerability of intranasally applied test substances.

  4. Tungsten as an innovative alloy element in the development of seamless tubular steels; Wolfram als neuartiges Legierungselement bei der Entwicklung von nahtlosen Leitungsrohrstaehlen

    Energy Technology Data Exchange (ETDEWEB)

    Pardun, M. [Mannesmann Forschungsinstitut, Duisburg (Germany); Vallourec and Mannesmann Tubes, Muelheim (Germany); Kloster, G.; Koschlig, B.; Niederhoff, K. [Vallourec and Mannesmann Tubes, Duesseldorf (Germany)

    2002-07-01

    Einsatztemperaturen stabilisiert. Bei der hier beschriebenen Entwicklung wurden verschiedene Legierungsvarianten mit Wolframgehalten im Bereich von 0,25 bis 0,50% und C-Aequivalenten nach IIW zwischen 0,33 und 0,42% untersucht. Neben der generellen Untersuchung der Einsetzbarkeit von Wolfram als Legierungselement bei nahtlosen Leitungsrohrstaehlen und dem Aspekt der Stabilisierung der Streckgrenze bei erhoehten Temperaturen wurden insbesondere folgende Ziele verfolgt: Entwicklung eines Leitungsrohrstahles der API-Guetestufe X60 bis X70 mit niedrigem Kohlenstoffaequivalent (Wolfram ist nicht in den gaengigen Berechnungsformeln enthalten); Untersuchung des Einflusses von Wolfram auf die Schweissbarkeit; Verbesserung der Sauergaseigenschaften durch Ersatz von Mangan durch Wolfram (Mangan gilt als seigerungsfoerderndes Element). Im Folgenden wird die Entwicklung des neuartigen Leitungsrohrstahles von der Laborstufe bis hin zur ersten betrieblichen Anwendung auf der Pilgerstrasse Duesseldorf-Rath der Vallourec and Mannesmann Tubes erlaeutert. Neben den mechanischen Eigenschaften wird ebenso auf die Korrosionseigenschaften wie die Schweissbarkeit eingegangen. (orig.)

  5. Wirksamkeit und Verträglichkeit von Cyclophosphamid bei Multipler Sklerose: Eine retrospektive Analyse

    OpenAIRE

    2008-01-01

    Cyclophosphamid (Endoxan) ist ein zytostatisches Medikament, welches wegen seiner immunsuppressiven Wirkung eine breite Anwendung in der Therapie systemischer Autoimmunerkrankungen findet. Es wird als Medikation bei schwerer chronisch-progressiver Multipler Sklerose empfohlen, um die weitere Progredienz einzuschränken oder zu verhindern. Bisherige klinische Studien über den Wert dieses therapeutischen Einsatzes liefern aber kontroverse Ergebnisse. Aus diesem Grund erschien es sinnvoll...

  6. An application of the zeolite/water adsorption technology for beer cooling; Die Anwendung der Zeolith/Wasser-Technologie zur Bierkuehlung

    Energy Technology Data Exchange (ETDEWEB)

    Maier-Laxhuber, P.; Schmidt, R.; Becky, A.; Woerz, R. [Zeo-Tech GmbH, Unterschleissheim (Germany)

    2002-08-01

    A reusable self-chilling keg (CoolKeg) with an integrated cooling technique based on zeolite/water adsorption technology has been developed. Over 20.000 self cooled party-kegs have been manufactured in 2001 for the home consumer market in Germany. The CoolKeg is a 20 l party-keg which provides chilled (7 C) beer within 45 minutes. (orig.) [German] Fuer die Kuehlung von Bier wurden selbstkuehlende Faesser entwickelt, die Zeolith/Wasser-Technologie als besonders umweltfreundliche Kuehltechnik beinhalten. Nach Gebrauch werden die Mehrwegfaesser in der Brauerei reaktiviert. (orig.)

  7. Doença de von Willebrand e anestesia Enfermedad de von Willebrand y anestesia Von Willebrand's disease and anesthesia

    OpenAIRE

    Fabiano Timbó Barbosa; Rafael Martins da Cunha; Luciano Timbó Barbosa

    2007-01-01

    JUSTIFICATIVA E OBJETIVOS: A doença de von Willebrand ocorre devido à mutação no cromossomo 12 e é caracterizada por deficiência qualitativa ou quantitativa do fator de von Willebrand. A diversidade de mutações leva ao aparecimento das mais variadas manifestações clínicas possibilitando a divisão dos pacientes em vários tipos e subtipos clínicos. A coagulopatia se manifesta basicamente através da disfunção plaquetária associada à diminuição dos níveis séricos do fator VIII coagulante. O objet...

  8. Transient flow processes in pipelines. Visualisation and calculation of cavitation in pipeline systems behind fast-closing control valves; Transiente Stroemungsvorgaenge in Rohrleitungen. Visualisierung und Berechnung von Kavitation in Rohrleitungssystemen hinter schnellschliessenden Regelklappen

    Energy Technology Data Exchange (ETDEWEB)

    Dudlik, A.; Schlueter, S. [Fraunhofer-Institut fuer Umwelt-, Sicherheits- und Energietechnik UMSICHT, Oberhausen (Germany); Prasser, H.M. [Forschungszentrum Rossendorf e.V. (FZR), Dresden (Germany)

    1997-12-01

    In this article, experimental results of the current BMBF research project are introduced. The transient pressure curves when closing a control valve quickly are measured and compared with the predictions of the project software. Flow visualisation shows that the computer model of the concentrated steam cavitation can be used in the application of the characterisation process. Due to the reduction in pressure in cavitating system, there is outgassing of air, which remains as dispersed phase in condensation and dampens the sudden condensation. For long periods of time with system pressures below the saturation partial pressures of the released gases, one must expect a reduced speed of wave propagation. [Deutsch] In diesem Beitrag werden Versuchsergebnisse des laufenden BMBF-Forschungsvorhabens vorgestellt. Es werden die transienten Druckverlaeufe beim Schnellschluss einer Regelklappe gemessen und mit den Vorhersagen der Projektsoftware verglichen. Die berechneten Druckspitzen liegen im Bereich der gemessenen Werte. Stroemungsvisualisierungen zeigen, dass das Rechenmodell der konzentrierten Dampfkavitation bei Anwendung des Charakteristikenverfahrens anwendbar ist. Es kommt durch die Druckabsenkung im kavitierenden System zur Ausgasung von Luft, die bei der Kondensation als disperse Phase verbleibt und die Kondensationsschlaege daempft. Fuer laengere Zeitperioden mit Systemdruecken unterhalb der Saettigungspartialdruecke der geloesten Gase muss mit einer verminderten Wellenausbreitungsgeschwindigkeit gerechnet werden. (orig.)

  9. Energy conservation in space HVAC systems. Selection of the optimum blower and use of EC motors with maximum efficiency; Energieeinsparung bei RLT-Anlagen. Wahl eines optimalen Ventilators und Einsatz von EC-Motoren mit hoechstem Wirkungsgrad

    Energy Technology Data Exchange (ETDEWEB)

    Albig, J. [Ziehl Abegg AG, Kuenzelsau (Germany)

    2003-08-01

    The contribution discusses the use of radial blowers in a central air conditioning unit, e.g. for supplying cold air to the freezers of a department store. The unit uses backward-curved, free blowers with direct drives and with EC external rotor motors. The motor works with electronic commutation and is connected to the 400 V three-phase current network together with a matched EC controller, with continuous adaptation of the rotational speed. [German] Der folgende Beitrag befasst sich mit der Anwendung von Radialventilatoren in einem Klimazentralgeraet (kurz RLT-Geraet). Dieses RLT-Geraet wird z.B. verwendet, um Geschaefte einer Kaufhaus-Kette fuer Tiefkuehlwaren mit klimatisierter Luft zu versorgen. Bei der ueberarbeiteten Konstruktion des RLT-Geraetes werden direkt angetriebene, freilaufende, rueckwaerts gekruemmte Ventilatoren mit EC-Aussenlaeufermotor verwendet. Der EC-Motor wird elektronisch kommutiert und zusammen mit dem abgestimmten EC-Controller am Drehstromnetz (400 Volt) betrieben. Er bietet die Moeglichkeit zur stufenlosen Drehzahlanpassung. (orig.)

  10. MASA NASAL CONGÉNITA: QUISTE EPIDERMOIDE Congenital nasal mass: epidermoid and dermoid cyst

    Directory of Open Access Journals (Sweden)

    Gilberto Eduardo Marrugo-Pardo

    2010-12-01

    Full Text Available Las masas nasales congénitas de la línea media son poco frecuentes, pero ante la sospecha clínica debe realizarse una valoración completa que incluya imágenes diagnósticas para descartar origen intracraneal. Se presenta un caso clínico con la presencia de dos entidades clínicas de diferentes características histológicas junto con una revisión de la literaturaCongenital midline nasal mass are infrequent but before the clinical suspicion should be carried out a complete evaluation that includes diagnostic images with the aim of ruled out intracraneal lesion. This paper presented a clinical case is with two clinical entities of different histological characteristic together with a revision of the literature.

  11. Comparison of nasal Midazolam with Ketamine versus nasal Midazolam as a premedication in children

    OpenAIRE

    Khatavkar, Sonal S; Bakhshi, Rochana G

    2014-01-01

    Background: T his study was done to compare effects of intranasal midazolam and intranasal midazolam with ketamine for premedication of children aged 1-12 yrs undergoing intermediate and major surgeries. Aims: Midazolam and Ketamine have already been used as premedicants in children. Our aim was to find out advantage of combination of midazolam with ketamine over midazolam by nasal route. Methods: Sixty children of age group 1-12 yrs of American Society of Anesthesiologists (ASA) grade 1 and ...

  12. Opportunities and challenges for the nasal administration of nanoemulsions.

    Science.gov (United States)

    Comfort, Claurice; Garrastazu, Gabriela; Pozzoli, Michele; Sonvico, Fabio

    2015-01-01

    Nasal delivery has become a growing area of interest for drug administration as a consequence of several practical advantages, such as ease of administration and non-invasiveness. Moreover, the avoidance of hepatic first-pass metabolism and rapid and efficient absorption across the permeable nasal mucosa offer a promising alternative to other traditional administration routes, such as oral or parenteral delivery. In fact, nasal delivery has been proposed for a number of applications, including local, systemic, direct nose-to-brain and mucosal vaccine delivery. Nanoemulsions, due to their stability, small droplet size and optimal solubilization properties, represent a versatile formulation approach suitable for several administration routes. Nanoemulsions demonstrated great potential in nasal drug delivery, increasing the absorption and the bioavailability of many drugs for systemic and nose-to-brain delivery. Furthermore, they act as an active component, i.e. an adjuvant, in nasal mucosal vaccinations, displaying the ability to induce robust mucosal immunity, high serum antibodies titres and a cellular immune response avoiding inflammatory response. Interestingly, nanoemulsions have not been proposed for the treatment of local ailments of the nose. Despite the promising results in vitro and in vitro, the application of nanoemulsions for nasal delivery in humans appears mainly hindered by the lack of detailed toxicology studies to determine the effect of these formulations on the nasal mucosa and cilia and the lack of extensive clinical trials.

  13. NASAL IN SITU GEL: A NOVEL DRUG DELIVERY SYSTEM

    Directory of Open Access Journals (Sweden)

    Dhrupesh panchal

    2012-06-01

    Full Text Available Over the past few decades, advances in the in situ gel technologies have spurred development in manymedical and biomedical applications including controlled drug delivery. Many novel in situ gel baseddelivery matrices have been designed and fabricated to fulfill the ever increasing needs of thepharmaceutical and medical fields. In situ gelling systems are liquid at room temperature but undergogelation when in contact with body fluids or change in pH. In situ gel forming drug delivery is a type ofmucoadhesive drug delivery system. The formation of gel depends on factors like temperaturemodulation, pH change, presence of ions and ultraviolet irradiation from which the drug gets released ina sustained and controlled manner. Nasal delivery is a promising drug delivery option where commondrug administrations such as intravenous, intramuscular or oral are inapplicable. Recently, it has beenshown that many drugs have better bioavailability by nasal route than the oral route. This has beenattributed to rich vasculature and a highly permeable structure of the nasal mucosa coupled withavoidance of hepatic first-pass elimination, gut wall metabolism and/or destruction in thegastrointestinal tract. The physiology of the nose presents obstacles but offers a promising route for noninvasivesystemic delivery of numerous therapies and debatably drug delivery route to the brain. Thusthis review focuses on nasal drug delivery, various aspects of nasal anatomy and physiology, nasal drugabsorption mechanisms, various nasal drug delivery systems and their applications in drug delivery.

  14. PRL-3 expression in nasal sinus squamous cell carcinoma

    Institute of Scientific and Technical Information of China (English)

    Zi-Hui Chen; Min-Ying Li

    2016-01-01

    Objective:To investigate the relationship between liver regeneration phosphatase-3 (PRL-3) with differentiation extent of nasal sinus squamous cell carcinoma, and molecular biological effects on the pathogenesis of nasal sinus squamous cell carcinoma to comprehend its relevance, so as to make early diagnosis of patients, and to give guidance to the prognosis. Methods:Immunohistochemistry was used to detect PRL-3 in 30 cases of different degrees of sinus nasal squamous cell carcinoma. 20 cases of normal nasal cavity of mucosa tissues were set as control. Results:The PRL-3 in all levels of sinonasal squamous cell carcinoma tissues, there was a significant difference compared with the normal nasal mucosa (P<0.05), squamous cell carcinoma and its expression increased with the grade with enhanced trend. Conclusions:PRL-3 expression increased significantly in sinonasal squamous cell carcinoma than in nasal polyp tissue, showed that it may be associated with squamous cell carcinoma of nasal sinus squamous cell carcinoma, may be the early event.

  15. Sense of smell in patients with bilateral nasal polyposis

    Directory of Open Access Journals (Sweden)

    Savović Slobodan N.

    2004-01-01

    Full Text Available Introduction Sense of smell is susceptible to various changes, both in physiological and in numerous pathological conditions. Of quantitative disorders of smell, hyposmia and anosmia are quite common, whereas of qualitative disorders parosmia is most frequent. The aim of this paper was to examine impact of bilateral nasal polyposis on olfactory function. Material and methods The research was carried out at the Nose, Ear and Throat Clinic in Novi Sad. It included 80 examinees, 40 (20 male, 20 female with bilateral nasal polyposis, while 40 examinees belonged to the control group (20 male, 20 female without symptoms of nasal polyposes. Fortunato-Niccolini olfactometer was used for this examination. Results and discussion In patients with bilateral nasal polyposis the average perception threshold values for examined odors were 15.50 ccm of odorous air, while in the control group they were 10,20 ccm of odorous air. The average identification threshold values for examined odors in patients with bilateral nasal polyposis were 18.80 ccm of odorous air, while in the control group they were 13.55 ccm of scented air. T-test showed that values of both tresholds were statistically significantly higher (p< 0,01 in patients with bilateral nasal polyposis in relation to the control group. Conclusion Olfactory deficit in patients with bilateral nasal polyposis is explained by difficult or impossible passage of odors into the olfactory region.

  16. Results of rhinoplasties of the nasal tip in Cienfuegos

    Directory of Open Access Journals (Sweden)

    Bernardo Félix Canto Vidal

    2015-04-01

    Full Text Available Background: the rhinoplasty of the nasal tip is one of the most difficult and challenging plastic surgeries the surgeon dedicated to the nasal deformities faces. Objective: exposing the results of the rhinoplasty accomplished to patients with nasal deformities. Methods: a descriptive study of results obtained in 145 patients who had a surgery to correct nasal deformities. They were attended at Dr. Gustavo Aldereguía Lima University General Hospital of Cienfuegos, in a period of 10 years. Results: in 56 patients surgery was headed for embracing the nasal tip; in 45 patients to the rotation of the nasal tip; and in 44 patients to the projection of the nasal tip. The technique of the banner with graft of cartilage of the septum and the ear was used. Conclusion: in the analyzed period, the rhinoplasty accomplished in the province of Cienfuegos had satisfactory results, because the patient’s expectations were satisfied with a reduction of the costs of risks for them due to the use of local anesthesia.

  17. Nasal infection due to Mycobacterium fortuitum.

    Science.gov (United States)

    Nguyen, D-Q; Righini, C; Darouassi, Y; Schmerber, S

    2011-09-01

    Mycobacterium fortuitum, a rapidly growing non-tuberculous atypical mycobacterium, is commonly found in soil and water. This organism generally causes skin, bone, and soft tissue infections following local trauma or surgical procedures, and in immunodeficient patients. The case reported here is, to our knowledge, the first published report of M. fortuitum nasal infection. The authors report the case of a 3-year-old girl with intranasal tumour-like swelling associated with cervical lymph nodes due to M. fortuitum infection. A combination of radical surgical debridement and prolonged therapy with several antimicrobial agents was required to completely eradicate the infection. This case report indicates that non-tuberculous mycobacterial infections should be considered after failure of conventional antibiotic therapy or when classical microbiological tests fail to identify the pathogen responsible for sinonasal and cervical infections. Copyright © 2011 Elsevier Masson SAS. All rights reserved.

  18. Ovarian carcinoma presenting as cutaneous nasal metastasis*

    Science.gov (United States)

    António, Ana Marta; Alves, João Vitor; Goulão, João; Bártolo, Elvira

    2016-01-01

    Metastatic ovarian cancer uncommonly presents with skin metastasis. When present, skin metastases of ovarian cancer are usually localized in the vicinity of the primary tumor. We report a case of a 58-year-old woman with a rapid growing erythematous, well-defined nodule localized on the left nasal ala. A skin biopsy was performed and histopathological and immunohistochemical findings were compatible with a cutaneous metastasis of adenocarcinoma. A systematic investigation revealed a bilateral ovarian cystadenocarcinoma associated with visceral dissemination, likely associated with nose cutaneous metastasis. We report a very uncommon case because of the presentation of ovarian carcinoma as cutaneous metastasis. To our knowledge, this atypical localization on the nose has not been described yet in the literature.

  19. The effect of nasal tramazoline with dexamethasone in obstructive sleep apnoea patients.

    Science.gov (United States)

    Koutsourelakis, Ioannis; Minaritzoglou, Aliki; Zakynthinos, Georgios; Vagiakis, Emmanouil; Zakynthinos, Spyros

    2013-10-01

    Although there is a strong correlation between oral/oro-nasal breathing and apnoea/hypopnoea index in patients with obstructive sleep apnoea and normal nasal resistance at wakefulness, it remains unknown whether the pharmacological prevention of potential nasal obstruction during sleep could decrease oral/oro-nasal breathing and increase nasal breathing and subsequently decrease the apnoea/hypopnoea index. This study evaluated the effect of a combination of a nasal decongestant with corticosteroid on breathing route pattern and apnoea/hypopnoea index. 21 patients with obstructive sleep apnoea (mean apnoea/hypopnoea index 31.1 events per hour) and normal nasal resistance at wakefulness were enrolled in a randomised crossover trial of 1 weeks' treatment with nasal tramazoline and dexamethasone compared with 1 weeks' treatment with nasal placebo. At the start and end of each treatment period, patients underwent nasal resistance measurement and overnight polysomnography with attendant measurement of breathing route pattern. Nasal tramazoline with dexamethasone was associated with decrease in oral/oro-nasal breathing epochs and concomitant increase in nasal breathing epochs, and mean decrease of apnoea/hypopnoea index by 21%. The change in nasal breathing epochs was inversely related to the change in apnoea/hypopnoea index (Rs=0.78; pnasal tramazoline with dexamethasone in OSA patients with normal nasal resistance at wakefulness can restore the preponderance of nasal breathing epochs and modestly improve apnoea/hypopnoea index.

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    Directory of Open Access Journals (Sweden)

    Bettina Rulofs

    2010-03-01

    Full Text Available Der vorliegende Beitrag beleuchtet die Bedeutung der Geschlechterordnung im Prozess der sportmedialen Kommunikation. Im Kern geht es um die Frage, inwiefern im Prozess der medialen Vermittlung von Sport traditionelle Geschlechterstereotype aufrechterhalten werden oder Möglichkeiten der Irritation solcher Stereotype bestehen. Dazu werden verschiedene Ebenen des massenmedialen Kommunikationsprozesses in den Blick genommen: die Medienprodukte, die Öffentlichkeitsarbeit und Selbst-Präsentation der Sportler/innen, die Medienrezeption und die Herstellungsprozesse von Medien in den Sportredaktionen. This article illustrates the relevance of gender in processes of sports media communication. The question in focus is in what way traditional gender stereotypes are perpetuated in the process of media communication in sport and how such stereotypes can be irritated. Therefore different levels of mass media communication are considered: the media products, the public relations of athletes and the presentation of themselves as athletes, the media-reception and the production processes in sport departments of media institutions.