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Sample records for narrow nose smooth

  1. Nasal base narrowing of the caucasian nose through the cerclage technique

    Directory of Open Access Journals (Sweden)

    Mocellin, Marcos

    2010-06-01

    Full Text Available Introduction: Several techniques can be performed to reduce the nasal base (narrowing, as skin resection vestibular columellar skin resection, resection of skin in elliptical lip narinary, sloughing of skin and advancements (VY technique of Bernstein and the use of cerclage sutures in the nasal base. Objective: To evaluate the technique of cerclage performed in the nasal base, through endonasal rhinoplasty without delivery of basic technique, in the Caucasian nose, reducing the distance inter-alar flare and correcting the wing with consequent improvement in nasal harmony in the whole face. Methods: A retrospective analysis by analysis of clinical documents and photos of 43 patients in whom cerclage was made of the nasal base by resecting skin ellipse in the region of the vestibule and the nasal base (modified technique of Weir using colorless mononylon® 4 "0" with a straight cutting needle. The study was conducted in 2008 and 2009 at Hospital of Paraná Institute of Otolaryngology - IPO in Curitiba, Parana - Brazil. Patients had a follow up ranging 7-12 months. Results: In 100% of cases was achieved an improvement in nasal harmony, by decreasing the inter-alar distance. Conclusion: The encircling with minimal resection of vestibular skin and the nasal base is an effective method for the narrowing of the nasal base in the Caucasian nose, with predictable results and easy to perform.

  2. Ear, Nose & Throat Issues & Down Syndrome

    Science.gov (United States)

    ... Throat Issues & Down Syndrome Ear, Nose & Throat Issues & Down Syndrome Ear, nose, and throat (ENT) problems are common ... What ENT Problems Are Common in Children With Down Syndrome? External Ear Canal Stenosis Stenotic ear canals (narrow ...

  3. Runny Nose

    Science.gov (United States)

    ... practice parameter update. Annals of Allergy, Asthma and Immunology. 2014;113:347. Stuffy nose. American Academy of Otolaryngology — Head and Neck Surgery. http://www.entnet.org/content/stuffy-nose. Accessed ...

  4. Your Nose

    Science.gov (United States)

    ... nose, you will also see hairs that can trap large particles, like dirt or pollen. If something ... Nemours Foundation, iStock, Getty Images, Corbis, Veer, Science Photo Library, Science Source Images, Shutterstock, and Clipart.com

  5. Comparison of aerodynamic noise from three nose-cylinder combinations

    Science.gov (United States)

    Guenther, R. A.; Reding, M. P.

    1970-01-01

    Results of experiments with three different cylinder and blunted nose combinations are discussed. Combinations include smooth cylinder with single 15 deg cone, smooth cylinder with double cone of 25 and 10 deg, and longitudinally corrugated cylinder with similar double cone.

  6. Avoiding Winter Nose Bleeds

    Institute of Scientific and Technical Information of China (English)

    1999-01-01

    WINTER is the best season for peopleto do cold-endurance exercises. But thedry, windy weather makes the moisturein the nasal mucosa evaporate quickly,reducing the elasticity of capillaries andmaking for frequent nose-bleeds.

  7. Nose Hill Artifacts

    Science.gov (United States)

    Hansen, Vivian

    2008-01-01

    A Blackfoot woman, caught in the act of adultery, was condemned at this site to have her nose cut off as a penalty for her actions. People do not know her story. The tribe cast it on the ground. And so She, Nose Hill, was named. John Laurie Boulevard holds her mound in a circlet of asphalt, defining the map of her "terra incognita." She is a park…

  8. Nose: Applied aspects in dermatology

    Directory of Open Access Journals (Sweden)

    Dammaningala Venkataramaiah Lakshmi

    2016-01-01

    Full Text Available Nose is the most prominent part of the mid-face and has important physiological, aesthetic and psychological functions. Skin diseases on the nose are commonly seen by dermatologists, otorhinolaryngologists, and plastic surgeons. Because of its exposed, highly visible localization, lesions on the skin of the nose are often noticed by patients themselves, typically very early in the course of the disease. Similarly, the dermatological lexicon is well known with descriptive terminologies, synonyms, acronyms, eponyms, toponyms, misnomers. We have tried to compile the anatomical applications of nose in cosmetology and dermatosurgery subspecialities with nasal eponyms and signs encountered in clinical dermatology that would be helpful for residents.

  9. Mechanoreceptors in the nose

    Directory of Open Access Journals (Sweden)

    Adil S. Abdal Razaq

    2015-03-01

    Full Text Available Nasal obstruction is a common symptom. Usually it is due to the presence of enlarged inferior turbinates, adenoid hypertrophy or pathological nasal mass. The most commonly encountered is nasal polyp. The presence of a physically obstructing mass causing the symptom can be easily explained. However, there are some patients with nasal polyp who do not have the feeling of congestion or nasal obstruction. There might be due to the mechanoreceptor that is free from stimulation despite the presence of the polyp. This review was made in the process of understanding the presence and type of mechanoreceptors in animal as well human nose.

  10. Lupus vulgaris of external nose.

    Science.gov (United States)

    Bhandary, Satheesh Kumar; Ranganna, B Usha

    2008-12-01

    Lupus vulgaris is the commonest form of cutaneous tuberculosis which commonly involve trunk and buttocks. Lupus vulgaris affecting nose and face, are rarely reported in India. This study reports an unusual case of lupus vulgaris involving the external nose that showed dramatic outcome after six months of anti- tubercular treatment.

  11. [Surgical anatomy of the nose].

    Science.gov (United States)

    Nguyen, P S; Bardot, J; Duron, J B; Jallut, Y; Aiach, G

    2014-12-01

    Thorough knowledge of the anatomy of the nose is an essential prerequisite for preoperative analysis and the understanding of surgical techniques. Like a tent supported by its frame, the nose is an osteo-chondral structure covered by a peri-chondroperiosteal envelope, muscle and cutaneous covering tissues. For didactic reasons, we have chosen to treat this chapter in the form of comments from eight key configurations that the surgeon should acquire before performing rhinoplasty.

  12. Smooth magnetogenesis

    CERN Document Server

    Campanelli, L

    2016-01-01

    In the Ratra scenario of inflationary magnetogenesis, the kinematic coupling between the photon and the inflaton undergoes a nonanalytical jump at the end of inflation. Using smooth interpolating analytical forms of the coupling function, we show that such unphysical jump does not invalidate the main prediction of the model, which still represents a viable mechanism for explaining cosmic magnetization. Nevertheless, there is a spurious result associated with the nonanaliticity of the coupling, to wit, the prediction that the spectrum of created photons has a power-law decay in the ultraviolet regime. This issue is discussed using both semiclassical approximation and smooth coupling functions.

  13. Smoothed Invariants

    CERN Document Server

    Dye, H A

    2011-01-01

    We construct two knot invariants. The first knot invariant is a sum constructed using linking numbers. The second is an invariant of flat knots and is a formal sum of flat knots obtained by smoothing pairs of crossings. This invariant can be used in conjunction with other flat invariants, forming a family of invariants. Both invariants are constructed using the parity of a crossing.

  14. 21 CFR 878.3680 - Nose prosthesis.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Nose prosthesis. 878.3680 Section 878.3680 Food... DEVICES GENERAL AND PLASTIC SURGERY DEVICES Prosthetic Devices § 878.3680 Nose prosthesis. (a) Identification. A nose prosthesis is a silicone rubber solid device intended to be implanted to augment...

  15. Airway smooth muscle growth in asthma: proliferation, hypertrophy, and migration.

    Science.gov (United States)

    Bentley, J Kelley; Hershenson, Marc B

    2008-01-01

    Increased airway smooth muscle mass is present in fatal and non-fatal asthma. However, little information is available regarding the cellular mechanism (i.e., hyperplasia vs. hypertrophy). Even less information exists regarding the functional consequences of airway smooth muscle remodeling. It would appear that increased airway smooth muscle mass would tend to increase airway narrowing and airflow obstruction. However, the precise effects of increased airway smooth muscle mass on airway narrowing are not known. This review will consider the evidence for airway smooth muscle cell proliferation and hypertrophy in asthma, potential functional effects, and biochemical mechanisms.

  16. Nose tip refinement using interdomal suture in caucasian nose

    Directory of Open Access Journals (Sweden)

    Pasinato, Rogério

    2012-01-01

    Full Text Available Introduction: Refinement of the nose tip can be accomplished by a variety of techniques, but currently, the use of sutures in the nasal tip with conservative resection of the alar cartilage is the most frequently recommended approach. Objective: To classify the nasal tip and to demonstrate the interdomal suture applied to nasal tip refinement in the Caucasian nose, as well as to provide a simple and practical presentation of the surgical steps. Method: Development of surgical algorithm for nasal tip surgery: 1. Interdomal suture (double binding suture, 2. Interdomal suture with alar cartilage weakening (cross-hatching, 3. Interdomal suture with cephalic removal of the alar cartilage (McIndoe technique based on the nasal tip type classification. This classification assesses the interdomal distance (angle of domal divergence and intercrural distance, domal arch width, cartilage consistency, and skin type. Interdomal suture is performed through endonasal rhinoplasty by basic technique without delivery (Converse-Diamond technique under local anesthesia Conclusion: This classification is simple and facilitates the approach of surgical treatment of the nasal tip through interdomal suture, systematizing and standardizing surgical maneuvers for better refinement of the Caucasian nose.

  17. Electronic Noses Using Quantitative Artificial Neural Networ

    Institute of Scientific and Technical Information of China (English)

    2001-01-01

    The present paper covers a new type of electronic nose(e-nose) with a four-sensor array,which has been applied to detecting gases quantitatively in the presence of interference. This e-nose has adapted fundamental aspects of relative error(RE) in changing quantitative analysis into the artificial neural network (ANN).. Thus, both the quantitative and the qualitative requirements for ANN in implementing e-nose can be satisfied. In addition, the e-nose uses only 4 sensors in the sensor array, and can be designed for different usages simply by changing one or two sensor(s). Various gases were tested by this kind of e-nose, including alcohol vapor, CO, liquefied-petrol-gas and CO2. Satisfactory quantitative results were obtained and no qualitative mistake in prediction was observed for the samples being mixed with interference gases.

  18. NOSE POLYPOSIS AND THE ANTIGENIC INDUCTION OF THE NOSE MUCOSA

    Directory of Open Access Journals (Sweden)

    Miško Zivic

    2000-01-01

    Full Text Available An estimate was done of the frequency of appearance of the immune response equivalents (lymph follicle neoformations, their nature and pathogenic importance. The samples of 100 nose polyps and para-nasal cavities were analyzed. On the basis of the examined material a classic image of andenomatous, fibromatous and angiomatous polyps that that can be either cystic or edematous was found out. The lining epithelium is disturbed in the sense of a greater presence of goblet-like cells with respect to the cylindrical cells; it goes even as far as to the partial goblet-cell metaplasia that even takes the form of the polyp denudation. In the case of a great number of polyps it is surprising that the lymph follicle neoformation appearance in the exposed to the antigenic and non-antigenic stimuli is very rare.

  19. Crooked nose: An update of management strategies

    Directory of Open Access Journals (Sweden)

    Wael K.A. Hussein

    2015-03-01

    Conclusions: Deformities of the deviated nose can be quite different from patient to patient, and that there is no one method that can be used for every deviated nose. Correction requires a complete understanding of the three-dimensional pathology and the time-related changes that develop as healing occurs.

  20. Synthetic smooth muscle in the outer blood plexus of the rhinarium skin of Lemur catta L.

    Science.gov (United States)

    Elofsson, Rolf; Kröger, Ronald H H

    2017-01-01

    The skin of the lemur nose tip (rhinarium) has arterioles in the outer vascular plexus that are endowed with an unusual coat of smooth muscle cells. Comparison with the arterioles of the same area in a number of unrelated mammalians shows that the lemur pattern is unique. The vascular smooth muscle cells belong to the synthetic type. The function of synthetic smooth muscles around the terminal vessels in the lemur rhinarium is unclear but may have additional functions beyond regulation of vessel diameter.

  1. Micro-Electronic Nose System

    Science.gov (United States)

    Zee, Frank C.

    2011-12-01

    The ability to "smell" various gas vapors and complex odors is important for many applications such as environmental monitoring for detecting toxic gases as well as quality control in the processing of food, cosmetics, and other chemical products for commercial industries. Mimicking the architecture of the biological nose, a miniature electronic nose system was designed and developed consisting of an array of sensor devices, signal-processing circuits, and software pattern-recognition algorithms. The array of sensors used polymer/carbon-black composite thin-films, which would swell or expand reversibly and reproducibly and cause a resistance change upon exposure to a wide variety of gases. Two types of sensor devices were fabricated using silicon micromachining techniques to form "wells" that confined the polymer/carbon-black to a small and specific area. The first type of sensor device formed the "well" by etching into the silicon substrate using bulk micromachining. The second type built a high-aspect-ratio "well" on the surface of a silicon wafer using SU-8 photoresist. Two sizes of "wells" were fabricated: 500 x 600 mum² and 250 x 250 mum². Custom signal-processing circuits were implemented on a printed circuit board and as an application-specific integrated-circuit (ASIC) chip. The circuits were not only able to measure and amplify the small resistance changes, which corresponded to small ppm (parts-per-million) changes in gas concentrations, but were also adaptable to accommodate the various characteristics of the different thin-films. Since the thin-films were not specific to any one particular gas vapor, an array of sensors each containing a different thin-film was used to produce a distributed response pattern when exposed to a gas vapor. Pattern recognition, including a clustering algorithm and two artificial neural network algorithms, was used to classify the response pattern and identify the gas vapor or odor. Two gas experiments were performed, one

  2. Relative Smooth Topological Spaces

    Directory of Open Access Journals (Sweden)

    B. Ghazanfari

    2009-01-01

    Full Text Available In 1992, Ramadan introduced the concept of a smooth topological space and relativeness between smooth topological space and fuzzy topological space in Chang's (1968 view points. In this paper we give a new definition of smooth topological space. This definition can be considered as a generalization of the smooth topological space which was given by Ramadan. Some general properties such as relative smooth continuity and relative smooth compactness are studied.

  3. Jihadism, Narrow and Wide

    DEFF Research Database (Denmark)

    Sedgwick, Mark

    2015-01-01

    The term “jihadism” is popular, but difficult. It has narrow senses, which are generally valuable, and wide senses, which may be misleading. This article looks at the derivation and use of “jihadism” and of related terms, at definitions provided by a number of leading scholars, and at media usage....... It distinguishes two main groups of scholarly definitions, some careful and narrow, and some appearing to match loose media usage. However, it shows that even these scholarly definitions actually make important distinctions between jihadism and associated political and theological ideology. The article closes...

  4. Bio-benchmarking of electronic nose sensors.

    Directory of Open Access Journals (Sweden)

    Amalia Z Berna

    Full Text Available BACKGROUND: Electronic noses, E-Noses, are instruments designed to reproduce the performance of animal noses or antennae but generally they cannot match the discriminating power of the biological original and have, therefore, been of limited utility. The manner in which odorant space is sampled is a critical factor in the performance of all noses but so far it has been described in detail only for the fly antenna. METHODOLOGY: Here we describe how a set of metal oxide (MOx E-Nose sensors, which is the most commonly used type, samples odorant space and compare it with what is known about fly odorant receptors (ORs. PRINCIPAL FINDINGS: Compared with a fly's odorant receptors, MOx sensors from an electronic nose are on average more narrowly tuned but much more highly correlated with each other. A set of insect ORs can therefore sample broader regions of odorant space independently and redundantly than an equivalent number of MOx sensors. The comparison also highlights some important questions about the molecular nature of fly ORs. CONCLUSIONS: The comparative approach generates practical learnings that may be taken up by solid-state physicists or engineers in designing new solid-state electronic nose sensors. It also potentially deepens our understanding of the performance of the biological system.

  5. Bio-Benchmarking of Electronic Nose Sensors

    Science.gov (United States)

    Berna, Amalia Z.; Anderson, Alisha R.; Trowell, Stephen C.

    2009-01-01

    Background Electronic noses, E-Noses, are instruments designed to reproduce the performance of animal noses or antennae but generally they cannot match the discriminating power of the biological original and have, therefore, been of limited utility. The manner in which odorant space is sampled is a critical factor in the performance of all noses but so far it has been described in detail only for the fly antenna. Methodology Here we describe how a set of metal oxide (MOx) E-Nose sensors, which is the most commonly used type, samples odorant space and compare it with what is known about fly odorant receptors (ORs). Principal Findings Compared with a fly's odorant receptors, MOx sensors from an electronic nose are on average more narrowly tuned but much more highly correlated with each other. A set of insect ORs can therefore sample broader regions of odorant space independently and redundantly than an equivalent number of MOx sensors. The comparison also highlights some important questions about the molecular nature of fly ORs. Conclusions The comparative approach generates practical learnings that may be taken up by solid-state physicists or engineers in designing new solid-state electronic nose sensors. It also potentially deepens our understanding of the performance of the biological system. PMID:19641604

  6. Correlates of Narrow Bracketing

    DEFF Research Database (Denmark)

    Koch, Alexander; Nafziger, Julia

    We examine whether different phenomena of narrow bracketing can be traced back to some common characteristic and whether and how different phenomena are related. We find that making dominated lottery choices or ignoring the endowment when making risky choices are related phenomena and are both as...

  7. Treating asthma means treating airway smooth muscle cells

    NARCIS (Netherlands)

    Zuyderduyn, S; Sukkar, M B; Fust, A; Dhaliwal, S; Burgess, J K

    2008-01-01

    Asthma is characterised by airway hyperresponsiveness, airway inflammation and airway remodelling. Airway smooth muscle cells are known to be the main effector cells of airway narrowing. In the present paper, studies will be discussed that have led to a novel view of the role of airway smooth muscle

  8. 21 CFR 874.4140 - Ear, nose, and throat bur.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Ear, nose, and throat bur. 874.4140 Section 874...) MEDICAL DEVICES EAR, NOSE, AND THROAT DEVICES Surgical Devices § 874.4140 Ear, nose, and throat bur. (a) Identification. An ear, nose, and throat bur is a device consisting of an interchangeable drill bit that...

  9. How to Use Nose Drops Properly

    Science.gov (United States)

    ... Use nose drops only as long as directed Store medications out of reach of children Copyright 2013, American Society of Health-System Pharmacists. All rights reserved. This material may not be reproduced, displayed, modified, or distributed ...

  10. Monitoring the Halitosis with an Electronic Nose

    Science.gov (United States)

    Marchetti, Enrico; Pennazza, Giorgio; Santonico, Marco; Capuano, Rosamaria; Mummolo, Stefano; Marzo, Giuseppe; Di Natale, Corrado

    2011-09-01

    Halitosis disease results in a distinctive volatile fingerprint of the individual exhaled breath. Here a QMB based electronic nose has been used to study such fingerprints. This study aimed at following the time evolution of halitosis conditions in patients undergoing two different treatments. Professional operators assessed oral odor, and their evaluation was used for classifier training. Results show that the electronic nose can identify the presence of oral malodor and the attenuation of the condition achieved by the application of the treatment.

  11. How to Harmonize the Ethnic Nose.

    Science.gov (United States)

    Grinfeld, Artur; Betelli, Rodrigo; Arruda, Guilherme; Almeida, Washington

    2016-12-01

    The demand for cosmetic surgery has significantly increased in the past few years mainly due to economic rise witnessed in Brazil. The state of Bahia has predominately Afro-descendant population with the same countrywide scenario, where the surgeon must be able to face challenges such as the specifics demands of rhinoplasty in an ethnic nose. It represents not only a different nasal variety from the Caucasoid, but also a complex anatomical feature, with its own peculiarities, as thicker and oilier skin, with bulky fibrous fatty tissue with numerous sebaceous glands. The nose tip features both inadequate projection and definition, including a short columella and underdeveloped nasal spine. The lower lateral cartilages are lower and thinner if compared with Caucasian noses. The nasal septum is short and fragile, whereas the dorsum is low and wide with deep nasion and wide obtuse angles between nasal bones. Finally, yet importantly, the nose base has increased interalar distance and excess of alar wing, with an ovoid, horizontal, and open nostril. Considering all these uniqueness, the existing challenges to approach an ethnic nose are clear. It requires skill and accurate surgical maneuvers to seek facial harmony while maintaining the characteristics that define the individual ethnicity and identity. Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.

  12. Smooth Neutrosophic Topological Spaces

    Directory of Open Access Journals (Sweden)

    M. K. EL Gayyar

    2016-08-01

    Full Text Available As a new branch of philosophy, the neutrosophy was presented by Smarandache in 1980. It was presented as the study of origin, nature, and scope of neutralities; as well as their interactions with different ideational spectra. The aim in this paper is to introduce the concepts of smooth neutrosophic topological space, smooth neutrosophic cotopological space, smooth neutrosophic closure, and smooth neutrosophic interior. Furthermore, some properties of these concepts will be investigated.

  13. Smooth Neutrosophic Topological Spaces

    OpenAIRE

    M. K. EL GAYYAR

    2016-01-01

    As a new branch of philosophy, the neutrosophy was presented by Smarandache in 1980. It was presented as the study of origin, nature, and scope of neutralities; as well as their interactions with different ideational spectra. The aim in this paper is to introduce the concepts of smooth neutrosophic topological space, smooth neutrosophic cotopological space, smooth neutrosophic closure, and smooth neutrosophic interior. Furthermore, some properties of these concepts will be investigated.

  14. A 21st century technique for food control: Electronic noses

    Energy Technology Data Exchange (ETDEWEB)

    Peris, Miguel, E-mail: mperist@qim.upv.es [Departamento de Quimica, Universidad Politecnica de Valencia, 46071 Valencia (Spain); Escuder-Gilabert, Laura [Departamento de Quimica Analitica, Universitat de Valencia, C/Vicente Andres Estelles s/n, E-46100 Burjasot, Valencia (Spain)

    2009-04-06

    This work examines the main features of modern electronic noses (e-noses) and their most important applications in food control in this new century. The three components of an electronic nose (sample handling system, detection system, and data processing system) are described. Special attention is devoted to the promising mass spectrometry based e-noses, due to their advantages over the more classical gas sensors. Applications described include process monitoring, shelf-life investigation, freshness evaluation, authenticity assessment, as well as other general aspects of the utilization of electronic noses in food control. Finally, some interesting remarks concerning the strengths and weaknesses of electronic noses in food control are also mentioned.

  15. Handbook of Machine Olfaction: Electronic Nose Technology

    Science.gov (United States)

    Pearce, Tim C.; Schiffman, Susan S.; Nagle, H. Troy; Gardner, Julian W.

    2003-02-01

    "Electronic noses" are instruments which mimic the sense of smell. Consisting of olfactory sensors and a suitable signal processing unit, they are able to detect and distinguish odors precisely and at low cost. This makes them very useful for a remarkable variety of applications in the food and pharmaceutical industry, in environmental control or clinical diagnostics and more. The scope covers biological and technical fundamentals and up-to-date research. Contributions by renowned international scientists as well as application-oriented news from successful "e-nose" manufacturers give a well-rounded account of the topic, and this coverage from R&D to applications makes this book a must-have read for e-nose researchers, designers and users alike.

  16. Progress of Biomimetic Artificial Nose and Tongue

    Science.gov (United States)

    Wang, Ping; Liu, Qingjun

    2009-05-01

    As two of the basic senses of human beings, olfaction and gustation play a very important role in daily life. These two types of chemical sensors are important for recognizing environmental conditions. Electronic nose and electronic tongue, which mimics animals' olfaction and gustation to detect odors and chemical components, have been carried out due to their potential commercial applications for biomedicine, food industry and environmental protection. In this report, the biomimetic artificial nose and tongue is presented. Firstly, the smell and taste sensors mimicking the mammalian olfaction and gustation was described, and then, some mimetic design of electronic nose and tongue for odorants and tastants detection are developed. Finally, olfactory and gustatory biosensors are presented as the developing trends of this field.

  17. Smooth K-Theory

    CERN Document Server

    Bunke, Ulrich

    2007-01-01

    We construct an analytic multiplicative model of smooth K-theory. We further introduce the notion of a smooth K-orientation of a proper submersion and define the associated push-forward which satisfies functoriality, compatibility with pull-back diagrams, and projection and bordism formulas. We construct a multiplicative lift of the Chern character from smooth K-theory to smooth rational cohomology and verify that the cohomological version of the Atiyah-Singer index theorem for families lifts to smooth cohomology.

  18. Computation with narrow CTCs

    CERN Document Server

    Say, A C Cem

    2011-01-01

    We examine some variants of computation with closed timelike curves (CTCs), where various restrictions are imposed on the memory of the computer, and the information carrying capacity and range of the CTC. We give full characterizations of the classes of languages recognized by polynomial time probabilistic and quantum computers that can send a single classical bit to their own past. Such narrow CTCs are demonstrated to add the power of limited nondeterminism to deterministic computers, and lead to exponential speedup in constant-space probabilistic and quantum computation. We show that, given a time machine with constant negative delay, one can implement CTC-based computations without the need to know about the runtime beforehand.

  19. Pediatric Obesity and Ear, Nose, and Throat Disorders

    Science.gov (United States)

    ... ENTCareers Marketplace Find an ENT Doctor Near You Pediatric Obesity and Ear, Nose, and Throat Disorders Pediatric ... of self-esteem, and isolation from their peers. Pediatric obesity and otolaryngic problems Otolaryngologists, or ear, nose, ...

  20. The Gendered Nose and its Lack: "Medieval" Nose-Cutting and its Modern Manifestations.

    Science.gov (United States)

    Skinner, Patricia

    2014-01-01

    Time magazine's cover photograph in August 2010 of a noseless Afghan woman beside the emotive strap line, "What happens if we leave Afghanistan," fuelled debate about the "medieval" practices of the Taliban, whose local commander had instructed her husband to take her nose and ears. Press reports attributed the violence to the Pashtun tradition that a dishonored husband "lost his nose." This equation of nose-cutting with tradition begs questions not only about the Orientalist lens of the western press when viewing Afghanistan, but also about the assumption that the word "medieval" can function as a label for such practices. A study of medieval nose-cutting suggests that its identification as an "eastern" practice should be challenged. Rather clearer is its connection with patriarchal values of authority and honor: the victims of such punishment have not always been women, but this is nevertheless a gendered punishment of the powerless by the powerful.

  1. Narrow, duplicated internal auditory canal

    Energy Technology Data Exchange (ETDEWEB)

    Ferreira, T. [Servico de Neurorradiologia, Hospital Garcia de Orta, Avenida Torrado da Silva, 2801-951, Almada (Portugal); Shayestehfar, B. [Department of Radiology, UCLA Oliveview School of Medicine, Los Angeles, California (United States); Lufkin, R. [Department of Radiology, UCLA School of Medicine, Los Angeles, California (United States)

    2003-05-01

    A narrow internal auditory canal (IAC) constitutes a relative contraindication to cochlear implantation because it is associated with aplasia or hypoplasia of the vestibulocochlear nerve or its cochlear branch. We report an unusual case of a narrow, duplicated IAC, divided by a bony septum into a superior relatively large portion and an inferior stenotic portion, in which we could identify only the facial nerve. This case adds support to the association between a narrow IAC and aplasia or hypoplasia of the vestibulocochlear nerve. The normal facial nerve argues against the hypothesis that the narrow IAC is the result of a primary bony defect which inhibits the growth of the vestibulocochlear nerve. (orig.)

  2. Seeing smells: development of an optoelectronic nose

    Directory of Open Access Journals (Sweden)

    Kenneth S. Suslick

    2007-06-01

    Full Text Available The development of an array of chemically-responsive dyes on a porous membrane and in its use as a general sensor for odors and volatile organic compounds (VOCs is reviewed. These colorimetric sensor arrays (CSA act as an "optoelectronic nose" by using an array of multiple dyes whose color changes are based on the full range of intermolecular interactions. The CSA is digitally imaged before and after exposure and the resulting difference map provides a digital fingerprint for any VOC or mixture of odorants. The result is an enormous increase in discriminatory power among odorants compared to prior electronic nose technologies. For the detection of biologically important analytes, including amines, carboxylic acids, and thiols, high sensitivities (ppbv have been demonstrated. The array is essentially non-responsive to changes in humidity due to the hydrophobicity of the dyes and membrane.

  3. Electronic Noses and Tongues in Wine Industry

    Directory of Open Access Journals (Sweden)

    Maria Luz Rodriguez-Mendez

    2016-10-01

    Full Text Available The quality of wines is usually evaluated by a sensory panel formed of trained experts or traditional chemical analysis. Over the last few decades, electronic noses and electronic tongues have been developed to determine the quality of foods and beverages. They consist of arrays of sensors with cross-sensitivity, combined with pattern recognition software, which provide a fingerprint of the samples that can be used to discriminate or classify the samples. This holistic approach is inspired by the method used in mammals to recognize food through their senses. They have been widely applied to the analysis of wines, including quality control, aging control or the detection of fraudulence, among others. In this paper, the current status of research and development in the field of electronic noses and tongues applied to the analysis of wines is reviewed. Their potential applications in the wine industry are described. The review ends with a final comment about expected future developments.

  4. Electronic Nose Study of Powdered Garlic

    Directory of Open Access Journals (Sweden)

    Rosa E. Baby

    2009-08-01

    Full Text Available An electronic nose was used to study the odour profile of garlic, separating the powered samples of eight cultivars and proving to be useful to discriminate garlic specimen dried by lyophilization and oven-dried and humidified specimen (before dried by both techniques for each cultivar. Pattern recognition and multivariate analysis of the electronic nose data has enabled to easily separate the garlic cultivars, to clearly discriminate the lyophilized or oven-dried specimen and the non humidified samples from the humidified powders maintaining, in every case, the cultivars identification. The humidification of lyophilized powders has shown a sharp separation of cultivars, otherwise, in the humidified oven-dried powders, their identification resulted less precise. This fact enabled to infer that lyophilized powders (either dry or humidified better retained their odour profile than oven-dried powders, maintaining the properties of each cultivar.

  5. Nose muscular dynamics: the tip trigonum.

    Science.gov (United States)

    Figallo, E E; Acosta, J A

    2001-10-01

    In 1995, the senior author (E.E.F.) published an article in which he described the musculus digastricus septi nasi labialis. In the article presented here, work carried out by anatomists and other researchers who, over the last two centuries, studied nose muscular dynamics is described. The present study is based on Gray's Anatomy, which, in 1858, first described the nasal tip muscles, along with the other nasal muscles. Later works not only used different terminology for these muscles but also ignored some, creating tremendous confusion. The study presented here provides an update of the exact terms, location, insertions, and muscle functions of the muscles of the nose. Each nose muscle is described with regard to the two portions able to produce separate contractions. In this study, the term "dual function" is used and characterizes the nasal mimetic muscles that do not have well-defined fascia. Therefore, there is doubt about the existence of a real nasal superficial muscle aponeurotic system. The musculus myrtiformis seems to have a dual function, inserting in the canine fosse and in the periosteum of the central incisors, forming two portions-one to the septum and the other to the nostril-each of which has specific functions. This study has been based on research in physiognomy, the science of expression. With regard to the basis for nose expressions, common anatomical research is excluded because it provides a different view of the dynamics studied to date. The term trigonum musculare apicis nasi defines the interaction of the musculi compressor narium minor and dilator naris anterior, connecting with the columellar bundle of the musculus digastricus and levering the nasal spine. This muscular trigone creates circular concentric and eccentric movements of the nasal tip.

  6. Electronic Noses for Environmental Monitoring Applications

    Directory of Open Access Journals (Sweden)

    Laura Capelli

    2014-10-01

    Full Text Available Electronic nose applications in environmental monitoring are nowadays of great interest, because of the instruments’ proven capability of recognizing and discriminating between a variety of different gases and odors using just a small number of sensors. Such applications in the environmental field include analysis of parameters relating to environmental quality, process control, and verification of efficiency of odor control systems. This article reviews the findings of recent scientific studies in this field, with particular focus on the abovementioned applications. In general, these studies prove that electronic noses are mostly suitable for the different applications reported, especially if the instruments are specifically developed and fine-tuned. As a general rule, literature studies also discuss the critical aspects connected with the different possible uses, as well as research regarding the development of effective solutions. However, currently the main limit to the diffusion of electronic noses as environmental monitoring tools is their complexity and the lack of specific regulation for their standardization, as their use entails a large number of degrees of freedom, regarding for instance the training and the data processing procedures.

  7. Rhinoplasty for the multiply revised nose.

    Science.gov (United States)

    Foda, Hossam M T

    2005-01-01

    To evaluate the problems encountered on revising a multiply operated nose and the methods used in correcting such problems. The study included 50 cases presenting for revision rhinoplasty after having had 2 or more previous rhinoplasties. An external rhinoplasty approach was used in all cases. Simultaneous septal surgery was done whenever indicated. All cases were followed for a mean period of 32 months (range, 1.5-8 years). Evaluation of the surgical result depended on clinical examination, comparison of pre- and postoperative photographs, and degree of patients' satisfaction with their aesthetic and functional outcome. Functionally, 68% suffered nasal obstruction that was mainly caused by septal deviations and nasal valve problems. Aesthetically, the most common deformities of the upper two thirds of the nose included pollybeak (64%), dorsal irregularities (54%), dorsal saddle (44%), and open roof deformity (42%), whereas the deformities of lower third included depressed tip (68%), tip contour irregularities (60%), and overrotated tip (42%). Nasal grafting was necessary in all cases; usually more than 1 type of graft was used in each case. Postoperatively, 79% of the patients, with preoperative nasal obstruction, reported improved breathing; 84% were satisfied with their aesthetic result; and only 8 cases (16%) requested further revision to correct minor deformities. Revision of a multiply operated nose is a complex and technically demanding task, yet, in a good percentage of cases, aesthetic as well as functional improvement are still possible.

  8. Breath alcohol, multisensor arrays, and electronic noses

    Science.gov (United States)

    Paulsson, Nils; Winquist, Fredrik

    1997-01-01

    The concept behind a volatile compound mapper, or electronic nose, is to use the combination of multiple gas sensors and pattern recognition techniques to detect and quantify substances in gas mixtures. There are several different kinds of sensors which have been developed during recent years of which the base techniques are conducting polymers, piezo electrical crystals and solid state devices. In this work we have used a combination of gas sensitive field effect devices and semiconducting metal oxides. The most useful pattern recognition routine was found to be ANNs, which is a mathematical approximation of the human neural network. The aim of this work is to evaluate the possibility of using electronic noses in field instruments to detect drugs, arson residues, explosives etc. As a test application we have chosen breath alcohol measurements. There are several reasons for this. Breath samples are a quite complex mixture contains between 200 and 300 substances at trace levels. The alcohol level is low but still possible to handle. There are needs for replacing large and heavy mobile instruments with smaller devices. Current instrumentation is rather sensitive to interfering substances. The work so far has dealt with sampling, how to introduce ethanol and other substances in the breath, correlation measurements between the electronic nose and headspace GC, and how to evaluate the sensor signals.

  9. Bioelectronic nose: Current status and perspectives.

    Science.gov (United States)

    Wasilewski, Tomasz; Gębicki, Jacek; Kamysz, Wojciech

    2017-01-15

    A characteristic feature of human and animal organs of smell is the ability to identify hundreds of thousands of odours. It is accompanied by particular smell sensations, which are a basic source of information about odour mixture. The main structural elements of biological smell systems are the olfactory receptors. Small differences in a structure of odorous molecules (odorants) can lead to significant change of odour, which is due to the fact that each of the olfactory receptors is coded with different gene and usually corresponds to different type of odour. Discovery and characterisation of the gene family coding the olfactory receptors contributed to the elaboration and development of the electronic smell systems, the so-called bioelectronic noses. The olfactory receptors are employed as a biological element in this type of instruments. An electronic system includes a converter part, which allows measurement and processing of generated signals. A suitable data analysis system is also required to visualise the results. Application potentialities of the bioelectronic noses are focused on the fields of economy and science where highly selective and sensitive analysis of odorous substances is required. The paper presents a review of the latest achievements and critical evaluation of the state of art in the field of bioelectronic noses.

  10. Smooth sandwich gravitational waves

    CERN Document Server

    Podolsky, J

    1999-01-01

    Gravitational waves which are smooth and contain two asymptotically flat regions are constructed from the homogeneous pp-waves vacuum solution. Motion of free test particles is calculated explicitly and the limit to an impulsive wave is also considered.

  11. smooth-muscle activity

    African Journals Online (AJOL)

    with atropine could not abolish the effect of the venom on smooth muscle. ... cholenergic factor with acetylcholine was confirmed using radioimmunoassay of ... peripheral nervous antagonists on the venom action are still uncertain. The present.

  12. Towards a chemiresistive sensor-integrated electronic nose: a review.

    Science.gov (United States)

    Chiu, Shih-Wen; Tang, Kea-Tiong

    2013-10-22

    Electronic noses have potential applications in daily life, but are restricted by their bulky size and high price. This review focuses on the use of chemiresistive gas sensors, metal-oxide semiconductor gas sensors and conductive polymer gas sensors in an electronic nose for system integration to reduce size and cost. The review covers the system design considerations and the complementary metal-oxide-semiconductor integrated technology for a chemiresistive gas sensor electronic nose, including the integrated sensor array, its readout interface, and pattern recognition hardware. In addition, the state-of-the-art technology integrated in the electronic nose is also presented, such as the sensing front-end chip, electronic nose signal processing chip, and the electronic nose system-on-chip.

  13. Mechanism for Influence of Nose Bluntness on Asymmetric Vortices

    Institute of Scientific and Technical Information of China (English)

    WANG Gang; LIANG Xin-Gang

    2004-01-01

    @@ Pressure distributions on slender bodies are measured at various roll angles; it is found that the side loads on the blunted-nose slender body are as small as one-third of that on a pointed-nose one, or even zero at some roll angles. Numerical simulation shows that different flow structures are generated on the leeside of the bodies with different noses. The results confirm that a structure of U-shaped horseshoe vortex develops on the top of the blunted nose due to the closed type of surface flow separation. The shear layer separated from the nose is entrapped into the horseshoe vortex core and forms two main vortices on the two sides of the body. The function of this structure is to hold in the two main nose vortices and to restrict the emergence of asymmetry.

  14. Modeling and Simulating Dynamics of Missiles with Deflectable Nose Control

    Institute of Scientific and Technical Information of China (English)

    Gao Yuan; Gu Liangxian; Pan Lei

    2009-01-01

    This article investigates the dynamic characteristics of deflectable nose missiles with rotary single-channel control. After introduction of effective attack and sideslip angles as well as quasi-body coordinates based on the spin characteristics of the missile's body, an integrated rigid kinetic model of missile with deflectable nose control is set up in the quasi-body coordinates considering the interaction between the missile's nose and body by using rootless multi-rigid-body system dynamics and is linearized. Then an analysis with simulation is conducted to investigate the coupling characteristics between the channels, the influences of nose deflection on the body and the dynamic characteristics of missile's body. The results indicate that various channels of missiles with deflectable nose control are coupled cross-linked; the nose deflection tends to make the body move in the opposite direction and, finally, evidences the correctness and reasonability of the kinetic model proposed by this article.

  15. Towards a Chemiresistive Sensor-Integrated Electronic Nose: A Review

    Directory of Open Access Journals (Sweden)

    Kea-Tiong Tang

    2013-10-01

    Full Text Available Electronic noses have potential applications in daily life, but are restricted by their bulky size and high price. This review focuses on the use of chemiresistive gas sensors, metal-oxide semiconductor gas sensors and conductive polymer gas sensors in an electronic nose for system integration to reduce size and cost. The review covers the system design considerations and the complementary metal-oxide-semiconductor integrated technology for a chemiresistive gas sensor electronic nose, including the integrated sensor array, its readout interface, and pattern recognition hardware. In addition, the state-of-the-art technology integrated in the electronic nose is also presented, such as the sensing front-end chip, electronic nose signal processing chip, and the electronic nose system-on-chip.

  16. BUTTON BATTERY - AN UNWITNESSED CAUSE OF BATTERED NOSE

    Directory of Open Access Journals (Sweden)

    Shailesh R

    2013-11-01

    Full Text Available ABSTRACT: The presence of foreign body in the nose is not uncommon condition. Various unusual foreign bodies in the nose have been report ed in the literature in which button battery is one of them. It is capable of extensive tissue damage by chemical or thermal burns. We describe a case of an unwitnessed button battery in the nose of 3 years old female child resulted in septal perforation KEYWORDS: Nasal Foreign Body; Button Battery; Septal Perforation

  17. Differential Electronic Nose in On-Line Dynamic Measurements

    Directory of Open Access Journals (Sweden)

    Osowski S.

    2014-12-01

    Full Text Available The paper presents application of differential electronic nose in the dynamic (on-line volatile measurement. First we compare the classical nose employing only one sensor array and its extension in the differential form containing two sensor arrays working in differential mode. We show that differential nose performs better at changing environmental conditions, especially the temperature, and well performs in the dynamic mode of operation. We show its application in recognition of different brands of tobacco

  18. Smoothing error pitfalls

    Science.gov (United States)

    von Clarmann, T.

    2014-09-01

    The difference due to the content of a priori information between a constrained retrieval and the true atmospheric state is usually represented by a diagnostic quantity called smoothing error. In this paper it is shown that, regardless of the usefulness of the smoothing error as a diagnostic tool in its own right, the concept of the smoothing error as a component of the retrieval error budget is questionable because it is not compliant with Gaussian error propagation. The reason for this is that the smoothing error does not represent the expected deviation of the retrieval from the true state but the expected deviation of the retrieval from the atmospheric state sampled on an arbitrary grid, which is itself a smoothed representation of the true state; in other words, to characterize the full loss of information with respect to the true atmosphere, the effect of the representation of the atmospheric state on a finite grid also needs to be considered. The idea of a sufficiently fine sampling of this reference atmospheric state is problematic because atmospheric variability occurs on all scales, implying that there is no limit beyond which the sampling is fine enough. Even the idealization of infinitesimally fine sampling of the reference state does not help, because the smoothing error is applied to quantities which are only defined in a statistical sense, which implies that a finite volume of sufficient spatial extent is needed to meaningfully discuss temperature or concentration. Smoothing differences, however, which play a role when measurements are compared, are still a useful quantity if the covariance matrix involved has been evaluated on the comparison grid rather than resulting from interpolation and if the averaging kernel matrices have been evaluated on a grid fine enough to capture all atmospheric variations that the instruments are sensitive to. This is, under the assumptions stated, because the undefined component of the smoothing error, which is the

  19. Ulcerative lupus vulgaris over nose, leading to cosmetic deformity.

    Science.gov (United States)

    Nair, Pragya A; Mehta, Malay J; Patel, Bhumi B

    2015-01-01

    Lupus vulgaris (LV), is a chronic and progressive form of secondary cutaneous tuberculosis. In India, it is commonly seen over buttocks, thighs, and legs whereas involvement of nose is quite rare. Ulcerative variant particularly over nose causes destruction of cartilage, leading to irreversible deformities and contracture. High-index of suspicion is required for early diagnosis and prevention of cosmetic deformity. A case of LV over nose in a young male with ulceration is reported who responded well to anti-tubercular therapy, but left with scarring of nose, which could have been prevented if adequate awareness regarding extra-pulmonary cases would have been practiced.

  20. Miniature sensor suitable for electronic nose applications

    DEFF Research Database (Denmark)

    Pinnaduwage, L. A.; Gehl, A. C.; Allman, S. L.;

    2007-01-01

    A major research effort has been devoted over the years for the development of chemical sensors for the detection of chemical and explosive vapors. However, the deployment of such chemical sensors will require the use of multiple sensors probably tens of sensors in a sensor package to achieve sel...... microcantilevers. The sensor can detect parts-per-trillion concentrations of DMMP within 10 s exposure times. The small size of the sensor makes it ideally suited for electronic nose applications. © 2007 American Institute of Physics....

  1. Nonequilibrium thermodynamics and Nose-Hoover dynamics.

    Science.gov (United States)

    Esposito, Massimiliano; Monnai, Takaaki

    2011-05-12

    We show that systems driven by an external force and described by Nose-Hoover dynamics allow for a consistent nonequilibrium thermodynamics description when the thermostatted variable is initially assumed in a state of canonical equilibrium. By treating the "real" variables as the system and the thermostatted variable as the reservoir, we establish the first and second law of thermodynamics. As for Hamiltonian systems, the entropy production can be expressed as a relative entropy measuring the system-reservoir correlations established during the dynamics.

  2. The Gendered Nose and its Lack: “Medieval” Nose-Cutting and its Modern Manifestations

    Science.gov (United States)

    Skinner, Patricia

    2014-01-01

    Time magazine’s cover photograph in August 2010 of a noseless Afghan woman beside the emotive strap line, “What happens if we leave Afghanistan,” fuelled debate about the “medieval” practices of the Taliban, whose local commander had instructed her husband to take her nose and ears. Press reports attributed the violence to the Pashtun tradition that a dishonored husband “lost his nose.” This equation of nose-cutting with tradition begs questions not only about the Orientalist lens of the western press when viewing Afghanistan, but also about the assumption that the word “medieval” can function as a label for such practices. A study of medieval nose-cutting suggests that its identification as an “eastern” practice should be challenged. Rather clearer is its connection with patriarchal values of authority and honor: the victims of such punishment have not always been women, but this is nevertheless a gendered punishment of the powerless by the powerful. PMID:24790391

  3. The Electronic Nose Training Automation Development

    Science.gov (United States)

    Schattke, Nathan

    2002-01-01

    The electronic nose is a method of using several sensors in conjunction to identify an unknown gas. Statistical analysis has shown that a large number of training exposures need to be performed in order to get a model that can be depended on. The number of training exposures needed is on the order of 1000. Data acquisition from the noses are generally automatic and built in. The gas generation equipment consists of a Miller-Nelson (MN) flow/temperature/humidity controller and a Kin-Tek (KT) trace gas generator. This equipment has been controlled in the past by an old data acquisition and control system. The new system will use new control boards and an easy graphical user interface. The programming for this is in the LabVIEW G programming language. A language easy for the user to make modifications to. This paper details some of the issues in selecting the components and programming the connections. It is not a primer on LabVIEW programming, a separate CD is being delivered with website files to teach that.

  4. Acquired smooth muscle hamartoma

    Directory of Open Access Journals (Sweden)

    Bari Arfan ul

    2006-01-01

    Full Text Available Smooth muscle hamartoma is an uncommon, usually congenital, cutaneous hyperplasia of the arrectores pilorum muscles. When it is acquired, it may be confused with Becker′s nevus. We report a case of this rare tumor in a 19-year-old man. The disease started several years ago as multiple small skin-colored papules that subsequently coalesced to form a large soft plaque on the back of the left shoulder. The diagnosis of acquired smooth muscle hamartoma was confirmed on histopathology. The patient was reassured about the benign nature of the lesion and was not advised any treatment.

  5. Revealed smooth nontransitive preferences

    DEFF Research Database (Denmark)

    Keiding, Hans; Tvede, Mich

    2013-01-01

    consumption bundle, all strictly preferred bundles are more expensive than the observed bundle. Our main result is that data sets can be rationalized by a smooth nontransitive preference relation if and only if prices can normalized such that the law of demand is satisfied. Market data sets consist of finitely...... many observations of price vectors, lists of individual incomes and aggregate demands. We apply our main result to characterize market data sets consistent with equilibrium behaviour of pure-exchange economies with smooth nontransitive consumers....

  6. The Meaning of Disfigurement in Wilhelm Hauff's "Dwarf Nose."

    Science.gov (United States)

    Blamires, David

    2002-01-01

    Notes that Wilhelm Hauff's fairy tale "Dwarf Nose" tells of a boy who is turned into a squirrel for seven years, then regains human form as a dwarf with a long nose before finally achieving normal adult proportions. Discusses how the story includes details that suggest a sexual interpretation. (SG)

  7. Smoothed Particle Hydrodynamic Simulator

    Energy Technology Data Exchange (ETDEWEB)

    2016-10-05

    This code is a highly modular framework for developing smoothed particle hydrodynamic (SPH) simulations running on parallel platforms. The compartmentalization of the code allows for rapid development of new SPH applications and modifications of existing algorithms. The compartmentalization also allows changes in one part of the code used by many applications to instantly be made available to all applications.

  8. Conceptual Design of Deployment Structure of Morphing Nose Cone

    Directory of Open Access Journals (Sweden)

    Junlan Li

    2013-01-01

    Full Text Available For a reusable space vehicle or a missile, the shape of the nose cone has a significant effect on the drag of the vehicle. In this paper, the concept of morphing nose cone is proposed to reduce the drag when the reentry vehicle flies back into the atmosphere. The conceptual design of the structure of morphing nose cone is conducted. Mechanical design and optimization approach are developed by employing genetic algorithm to find the optimal geometric parameters of the morphing structure. An example is analyzed by using the proposed method. The results show that optimal solution supplies the minimum position error. The concept of morphing nose cone will provide a novel way for the drag reduction of reentry vehicle. The proposed method could be practically used for the design and optimization of the deployable structure of morphing nose cone.

  9. Drug delivery systems from nose to brain.

    Science.gov (United States)

    Misra, Ambikanandan; Kher, Gitanjali

    2012-09-01

    The treatment of brain disorders is particularly challenging due to the presence of a variety of formidable obstacles to deliver drugs selectively and effectively to the brain. Blood-brain-barrier (BBB) constitutes the major obstacle to the uptake of drugs into the brain following systemic administration. Intranasal delivery offers a non-invasive and convenient method to bypass the BBB and delivery of therapeutics directly to the brain. The review discusses the potential of intranasal route to deliver drugs to the brain, the mechanisms and pathways of direct nose to brain drug transport, the various factors influencing transnasal drug absorption, the conventional and novel intranasal drug delivery systems, the various intranasal drug delivery techniques and devices, and examples of brain drug transport that have been feasible in treating various brain disorders. Moreover, products on the market, investigational drugs, and the author's perceptions about the prospect of intranasal delivery for treating brain disorders are also been discussed.

  10. Development of Surface Acoustic Wave Electronic Nose

    Directory of Open Access Journals (Sweden)

    S.K. Jha

    2010-07-01

    Full Text Available The paper proposes an effective method to design and develop surface acoustic wave (SAW sensor array-based electronic nose systems for specific target applications. The paper suggests that before undertaking full hardware development empirically through hit and trial for sensor selection, it is prudent to develop accurate sensor array simulator for generating synthetic data and optimising sensor array design and pattern recognition system. The latter aspects are most time-consuming and cost-intensive parts in the development of an electronic nose system. This is because most of the electronic sensor platforms, circuit components, and electromechanical parts are available commercially-off-the-shelve (COTS, whereas knowledge about specific polymers and data analysis software are often guarded due to commercial or strategic interests. In this study, an 11-element SAW sensor array is modelled to detect and identify trinitrotoluene (TNT and dinitrotoluene (DNT explosive vapours in the presence of toluene, benzene, di-methyl methyl phosphonate (DMMP and humidity as interferents. Additive noise sources and outliers were included in the model for data generation. The pattern recognition system consists of: (i a preprocessor based on logarithmic data scaling, dimensional autoscaling, and singular value decomposition-based denoising, (ii principal component analysis (PCA-based feature extractor, and (iii an artificial neural network (ANN classifier. The efficacy of this approach is illustrated by presenting detailed PCA analysis and classification results under varied conditions of noise and outlier, and by analysing comparative performance of four classifiers (neural network, k-nearest neighbour, naïve Bayes, and support vector machine.Defence Science Journal, 2010, 60(4, pp.364-376, DOI:http://dx.doi.org/10.14429/dsj.60.493

  11. Smooth Neighborhood Structures in a Smooth Topological Spaces

    Directory of Open Access Journals (Sweden)

    A. A. Ramadan

    2010-01-01

    Full Text Available Various concepts related to a smooth topological spaces have been introduced and relations among them studied by several authors (Chattopadhyay, Ramadan, etc. In this study, we presented the notions of three sorts of neighborhood structures of a smooth topological spaces and give some of their properties which are results by Ying extended to smooth topological spaces.

  12. Advances in Electronic-Nose Technologies Developed for Biomedical Applications

    Directory of Open Access Journals (Sweden)

    Alphus D. Wilson

    2011-01-01

    Full Text Available The research and development of new electronic-nose applications in the biomedical field has accelerated at a phenomenal rate over the past 25 years. Many innovative e-nose technologies have provided solutions and applications to a wide variety of complex biomedical and healthcare problems. The purposes of this review are to present a comprehensive analysis of past and recent biomedical research findings and developments of electronic-nose sensor technologies, and to identify current and future potential e-nose applications that will continue to advance the effectiveness and efficiency of biomedical treatments and healthcare services for many years. An abundance of electronic-nose applications has been developed for a variety of healthcare sectors including diagnostics, immunology, pathology, patient recovery, pharmacology, physical therapy, physiology, preventative medicine, remote healthcare, and wound and graft healing. Specific biomedical e-nose applications range from uses in biochemical testing, blood-compatibility evaluations, disease diagnoses, and drug delivery to monitoring of metabolic levels, organ dysfunctions, and patient conditions through telemedicine. This paper summarizes the major electronic-nose technologies developed for healthcare and biomedical applications since the late 1980s when electronic aroma detection technologies were first recognized to be potentially useful in providing effective solutions to problems in the healthcare industry.

  13. Kinetic narrowing of size distribution

    Science.gov (United States)

    Dubrovskii, V. G.

    2016-05-01

    We present a model that reveals an interesting possibility for narrowing the size distribution of nanostructures when the deterministic growth rate changes its sign from positive to negative at a certain stationary size. Such a behavior occurs in self-catalyzed one-dimensional III-V nanowires and more generally whenever a negative "adsorption-desorption" term in the growth rate is compensated by a positive "diffusion flux." By asymptotically solving the Fokker-Planck equation, we derive an explicit representation for the size distribution that describes either Poissonian broadening or self-regulated narrowing depending on the parameters. We show how the fluctuation-induced spreading of the size distribution can be completely suppressed in systems with size self-stabilization. These results can be used for obtaining size-uniform ensembles of different nanostructures.

  14. Smoothness of limit functors

    Indian Academy of Sciences (India)

    Benedictus Margaux

    2015-05-01

    Let be a scheme. Assume that we are given an action of the one dimensional split torus $\\mathbb{G}_{m,S}$ on a smooth affine -scheme $\\mathfrak{X}$. We consider the limit (also called attractor) subfunctor $\\mathfrak{X}_{}$ consisting of points whose orbit under the given action `admits a limit at 0’. We show that $\\mathfrak{X}_{}$ is representable by a smooth closed subscheme of $\\mathfrak{X}$. This result generalizes a theorem of Conrad et al. (Pseudo-reductive groups (2010) Cambridge Univ. Press) where the case when $\\mathfrak{X}$ is an affine smooth group and $\\mathbb{G}_{m,S}$ acts as a group automorphisms of $\\mathfrak{X}$ is considered. It also occurs as a special case of a recent result by Drinfeld on the action of $\\mathbb{G}_{m,S}$ on algebraic spaces (Proposition 1.4.20 of Drinfeld V, On algebraic spaces with an action of $\\mathfrak{G}_{m}$, preprint 2013) in case is of finite type over a field.

  15. "Credit Markets and Narrow Banking"

    OpenAIRE

    Ronnie Phillips

    1992-01-01

    Maurice Allais's view that the credit created by fractional reserve banking is equivalent to counterfeiting has led him to recommend the separation of the depository and lending functions of banks. This proposal has recently been reintroduced by James Tobin and others under the term "narrow banking." Proponents cite the potential for enhanced safety of the payments mechanism and the elimination of costs associated with the preses system of Federal deposit insurance. This plan resembles the "1...

  16. Anti-smooth muscle antibody

    Science.gov (United States)

    ... medlineplus.gov/ency/article/003531.htm Anti-smooth muscle antibody To use the sharing features on this page, please enable JavaScript. Anti-smooth muscle antibody is a blood test that detects the ...

  17. EMBEDDING FLOWS AND SMOOTH CONJUGACY

    Institute of Scientific and Technical Information of China (English)

    ZHANGMEIRONG; LIWEIGU

    1997-01-01

    The authors use the functional equation for embedding vector fields to study smooth embedding flows of one-dimensional diffeomorphisms. The existence and uniqueness for smooth embedding flows and vector fields are proved. As an application of embedding flows, some classification results about local and giobal diffeomorphisms under smooth conjugacy are given.

  18. 21 CFR 874.4250 - Ear, nose, and throat electric or pneumatic surgical drill.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Ear, nose, and throat electric or pneumatic... AND HUMAN SERVICES (CONTINUED) MEDICAL DEVICES EAR, NOSE, AND THROAT DEVICES Surgical Devices § 874.4250 Ear, nose, and throat electric or pneumatic surgical drill. (a) Identification. An ear, nose,...

  19. 21 CFR 874.4350 - Ear, nose, and throat fiberoptic light source and carrier.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Ear, nose, and throat fiberoptic light source and... HUMAN SERVICES (CONTINUED) MEDICAL DEVICES EAR, NOSE, AND THROAT DEVICES Surgical Devices § 874.4350 Ear, nose, and throat fiberoptic light source and carrier. (a) Identification. An ear, nose, and...

  20. 21 CFR 874.5220 - Ear, nose, and throat drug administration device.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Ear, nose, and throat drug administration device... SERVICES (CONTINUED) MEDICAL DEVICES EAR, NOSE, AND THROAT DEVICES Therapeutic Devices § 874.5220 Ear, nose, and throat drug administration device. (a) Identification. An ear, nose, and throat...

  1. 21 CFR 874.5300 - Ear, nose, and throat examination and treatment unit.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Ear, nose, and throat examination and treatment... HUMAN SERVICES (CONTINUED) MEDICAL DEVICES EAR, NOSE, AND THROAT DEVICES Therapeutic Devices § 874.5300 Ear, nose, and throat examination and treatment unit. (a) Identification. An ear, nose, and...

  2. Impacts of Deflection Nose on Ballistic Trajectory Control Law

    Directory of Open Access Journals (Sweden)

    Bo Zhang

    2014-01-01

    Full Text Available The deflection of projectile nose is aimed at changing the motion of the projectile in flight with the theory of motion control and changing the exterior ballistics so as to change its range and increase its accuracy. The law of external ballistics with the deflectable nose is considered as the basis of the design of a flight control system and an important part in the process of projectile development. Based on the existing rigid external ballistic model, this paper establishes an external ballistic calculation model for deflectable nose projectile and further establishes the solving programs accordingly. Different angle of attack, velocity, coefficients of lift, resistance, and moment under the deflection can be obtained in this paper based on the previous experiments and emulation researches. In the end, the author pointed out the laws on the impaction of external ballistic trajectory by the deflection of nose of the missile.

  3. A Compact and Low Cost Electronic Nose for Aroma Detection

    Directory of Open Access Journals (Sweden)

    Ramón Gallardo Caballero

    2013-04-01

    Full Text Available This article explains the development of a prototype of a portable and a very low-cost electronic nose based on an mbed microcontroller. Mbeds are a series of ARM microcontroller development boards designed for fast, flexible and rapid prototyping. The electronic nose is comprised of an mbed, an LCD display, two small pumps, two electro-valves and a sensor chamber with four TGS Figaro gas sensors. The performance of the electronic nose has been tested by measuring the ethanol content of wine synthetic matrices and special attention has been paid to the reproducibility and repeatability of the measurements taken on different days. Results show that the electronic nose with a neural network classifier is able to discriminate wine samples with 10, 12 and 14% V/V alcohol content with a classification error of less than 1%.

  4. The air-conditioning capacity of the human nose.

    Science.gov (United States)

    Naftali, Sara; Rosenfeld, Moshe; Wolf, Michael; Elad, David

    2005-04-01

    The nose is the front line defender of the respiratory system. Unsteady simulations in three-dimensional models have been developed to study transport patterns in the human nose and its overall air-conditioning capacity. The results suggested that the healthy nose can efficiently provide about 90% of the heat and the water fluxes required to condition the ambient inspired air to near alveolar conditions in a variety of environmental conditions and independent of variations in internal structural components. The anatomical replica of the human nose showed the best performance and was able to provide 92% of the heating and 96% of the moisture needed to condition the inspired air to alveolar conditions. A detailed analysis explored the relative contribution of endonasal structural components to the air-conditioning process. During a moderate breathing effort, about 11% reduction in the efficacy of nasal air-conditioning capacity was observed.

  5. Histopathology confirms white-nose syndrome in bats in Europe

    Science.gov (United States)

    Pikula, J.; Bandouchova, H.; Novotny, L.; Meteyer, C.U.; Zukal, J.; Irwin, N.R.; Zima, J.; Martinkova, N.

    2012-01-01

    White-nose syndrome, associated with the fungal skin infection geomycosis, caused regional population collapse in bats in North America. Our results, based on histopathology, show the presence of white-nose syndrome in Europe. Dermatohistopathology on two bats (Myotis myotis) found dead in March 2010 with geomycosis in the Czech Republic had characteristics resembling Geomyces destructans infection in bats confirmed with white-nose syndrome in US hibernacula. In addition, a live M. myotis, biopsied for histopathology during hibernation in April 2011, had typical fungal infection with cupping erosion and invasion of muzzle skin diagnostic for white-nose syndrome and conidiospores identical to G. destructans that were genetically confirmed as G. destructans. ?? Wildlife Disease Association 2012.

  6. Evaluating Soil Moisture Status Using an e-Nose

    Directory of Open Access Journals (Sweden)

    Andrzej Bieganowski

    2016-06-01

    Full Text Available The possibility of distinguishing different soil moisture levels by electronic nose (e-nose was studied. Ten arable soils of various types were investigated. The measurements were performed for air-dry (AD soils stored for one year, then moistened to field water capacity and finally dried within a period of 180 days. The volatile fingerprints changed during the course of drying. At the end of the drying cycle, the fingerprints were similar to those of the initial AD soils. Principal component analysis (PCA and artificial neural network (ANN analysis showed that e-nose results can be used to distinguish soil moisture. It was also shown that different soils can give different e-nose signals at the same moistures.

  7. An electronic nose for quantitative determination of gas concentrations

    Science.gov (United States)

    Jasinski, Grzegorz; Kalinowski, Paweł; Woźniak, Łukasz

    2016-11-01

    The practical application of human nose for fragrance recognition is severely limited by the fact that our sense of smell is subjective and gets tired easily. Consequently, there is considerable need for an instrument that can be a substitution of the human sense of smell. Electronic nose devices from the mid 1980s are used in growing number of applications. They comprise an array of several electrochemical gas sensors with partial specificity and a pattern recognition algorithms. Most of such systems, however, is only used for qualitative measurements. In this article usage of such system in quantitative determination of gas concentration is demonstrated. Electronic nose consist of a sensor array with eight commercially available Taguchi type gas sensor. Performance of three different pattern recognition algorithms is compared, namely artificial neural network, partial least squares regression and support vector machine regression. The electronic nose is used for ammonia and nitrogen dioxide concentration determination.

  8. Electronic Nose Odor Classification with Advanced Decision Tree Structures

    Directory of Open Access Journals (Sweden)

    S. Guney

    2013-09-01

    Full Text Available Electronic nose (e-nose is an electronic device which can measure chemical compounds in air and consequently classify different odors. In this paper, an e-nose device consisting of 8 different gas sensors was designed and constructed. Using this device, 104 different experiments involving 11 different odor classes (moth, angelica root, rose, mint, polis, lemon, rotten egg, egg, garlic, grass, and acetone were performed. The main contribution of this paper is the finding that using the chemical domain knowledge it is possible to train an accurate odor classification system. The domain knowledge about chemical compounds is represented by a decision tree whose nodes are composed of classifiers such as Support Vector Machines and k-Nearest Neighbor. The overall accuracy achieved with the proposed algorithm and the constructed e-nose device was 97.18 %. Training and testing data sets used in this paper are published online.

  9. Questions and Answers: Runny Nose (with Green or Yellow Mucus)

    Science.gov (United States)

    ... Get Smart: Know When Antibiotics Work on the Farm Get Smart About Antibiotics Week One Page Sheet: Runny Nose ... Get Smart: Know When Antibiotics Work on the Farm Get Smart About Antibiotics Week Format: Select one PDF [194 ...

  10. Long-Term Complications of Button Batteries in the Nose.

    Science.gov (United States)

    Bakshi, Satvinder Singh; Coumare, V Nirmal; Priya, Madhu; Kumar, Sithananda

    2016-03-01

    One of the common emergencies presenting to the emergency department is a child who has inserted a foreign body into their nose. Of the various things that children insert accidently, the most dangerous are button batteries. We followed up 11 cases of children with history of button battery insertion in the nose for 1 year. We found that all of the patients had developed a septal perforation; other sequelae included nasal adhesions and saddle nose. WHY SHOULD AN EMERGENCY PHYSICIAN BE AWARE OF THIS?: Button batteries in the nose are dangerous and can lead to early complications with long-term consequences for the patients. Early diagnosis is required so that they can be removed as soon as possible to prevent the development of complications and long-term sequelae. Copyright © 2016 Elsevier Inc. All rights reserved.

  11. Cough reflex sensitization from esophagus and nose.

    Science.gov (United States)

    Hennel, Michal; Brozmanova, Mariana; Kollarik, Marian

    2015-12-01

    The diseases of the esophagus and nose are among the major factors contributing to chronic cough although their role in different patient populations is debated. Studies in animal models and in humans show that afferent C-fiber activators applied on esophageal or nasal mucosa do not initiate cough, but enhance cough induced by inhaled irritants. These results are consistent with the hypothesis that activation of esophageal and nasal C-fibers contribute to cough reflex hypersensitivity observed in chronic cough patients with gastroesophageal reflux disease (GERD) and chronic rhinitis, respectively. The afferent nerves mediating cough sensitization from the esophagus are probably the neural crest-derived vagal jugular C-fibers. In addition to their responsiveness to high concentration of acid typical for gastroesophageal reflux (pH cough sensitization are less understood. Increased cough reflex sensitivity was also reported in many patients with GERD or rhinitis who do not complain of cough indicating that additional endogenous or exogenous factors may be required to develop chronic coughing in these diseases.

  12. Multifunctionalized cantilever systems for electronic nose applications.

    Science.gov (United States)

    Yoo, Yong Kyoung; Chae, Myung-Sic; Kang, Ji Yoon; Kim, Tae Song; Hwang, Kyo Seon; Lee, Jeong Hoon

    2012-10-02

    Multiple target detection using a cantilever is essential for biosensor, chemical sensor, and electronic nose systems. We report a novel microcantilever array chip that includes four microreaction chambers in a chip, which consequently contains four different functionalized surfaces for multitarget detection. For model tests, we designed microcantilever chips and demonstrated the ability of binding of 2,4-dinitrotoluene (DNT) targets onto four different surfaces. We used peptide receptors that are known to have highly selective binding. By simply using four microreaction chambers, we immobilized DNT specific peptide (HPNFSKYILHQRC; SP), DNT nonspecific peptide (TSMLLMSPKHQAC; NSP), and self-assembled monolayer (SAM) as well as a bare cantilever. After flowing DNT gases through the cantilever chip, we could monitor the four different binding signals simultaneously. The shifts in NSP provided information as a negative control because it contained information of temperature fluctuations and mechanical vibration from gas flow. By utilizing the differential signal of the SP and NSP, we acquired 7.5 Hz in resonant responses that corresponds with 160 part per billion (ppb) DNT concentration, showing the exact binding response by eliminating the inevitable thermal noise, vibration noise, as well as humidity effects on the peptide surface.

  13. Sensors: From biosensors to the electronic nose

    Directory of Open Access Journals (Sweden)

    Aparicio, Ramón

    2002-03-01

    Full Text Available The recent advances in sensor devices have allowed the developing of new applications in many technological fields. This review describes the current state-of-the-art of this sensor technology, placing special emphasis on the food applications. The design, technology and sensing mechanism of each type of sensor are analysed. A description of the main characteristics of the electronic nose and electronic tongue (taste sensors is also given. Finally, the applications of some statistical procedures in sensor systems are described briefly.Los recientes avances en los sistemas de sensores han permitido el desarrollo de nuevas aplicaciones en muchos campos tecnológicos. Este artículo de revisión describe el estado actual de esta nueva tecnología, con especial énfasis en las aplicaciones alimentarias. El diseño, la tecnología y el mecanismo sensorial de cada tipo de sensor son analizados en el artículo. También se describen las principales características de la nariz y la lengua electrónica (sensores de sabor. Finalmente, se describe brevemente el uso de algunos procedimientos estadísticos en sistemas de sensores.

  14. E-nose identification of milk somatic cell count

    OpenAIRE

    İNALPULAT, Melis; Kızıl, Ünal; Bilgücü, Ertuğrul; GENÇ, Levent

    2016-01-01

    Mastitis is a common disease among dairy animals which causes serious economic losses. It can be diagnosed via diverse clinical findings, while milk somatic cell count (SCC) is accepted as a key indicator. However, determination of SCC with traditional methods is time consuming and laborious. This paper focuses on the ability of electronic nose (e-nose) system containing 12 different metal oxide sensors (MOS) to discriminate milks with somatic cell counts (SCC) above a th...

  15. Lupus vulgaris of external nose--a case report.

    Science.gov (United States)

    Arunkumar, J S; Naveen, K N; Prasad, K C; Santhosh, S G; Hegde, J S

    2013-02-01

    Lupus vulgaris is the most common morphological variant of cutaneous tuberculosis accounting for approximately 59% of cases of cutaneous tuberculosis in India. We present a case of lupus vulgaris of external nose diagnosed early and treated with CAT-3 RNTCP regimen for six months without any nasal deformity except for a small scar over the dorsum of the nose. Patient followed up for one year after completion of the prescribed regimen, there being no recurrence of the lesion.

  16. The spectacular human nose: an amplifier of individual quality?

    Directory of Open Access Journals (Sweden)

    Åse Kristine Rognmo Mikalsen

    2014-04-01

    Full Text Available Amplifiers are signals that improve the perception of underlying differences in quality. They are cost free and advantageous to high quality individuals, but disadvantageous to low quality individuals, as poor quality is easier perceived because of the amplifier. For an amplifier to evolve, the average fitness benefit to the high quality individuals should be higher than the average cost for the low quality individuals. The human nose is, compared to the nose of most other primates, extraordinary large, fragile and easily broken—especially in male–male interactions. May it have evolved as an amplifier among high quality individuals, allowing easy assessment of individual quality and influencing the perception of attractiveness? We tested the latter by manipulating the position of the nose tip or, as a control, the mouth in facial pictures and had the pictures rated for attractiveness. Our results show that facial attractiveness failed to be influenced by mouth manipulations. Yet, facial attractiveness increased when the nose tip was artificially centered according to other facial features. Conversely, attractiveness decreased when the nose tip was displaced away from its central position. Our results suggest that our evaluation of attractiveness is clearly sensitive to the centering of the nose tip, possibly because it affects our perception of the face’s symmetry and/or averageness. However, whether such centering is related to individual quality remains unclear.

  17. Applications and Advances in Electronic-Nose Technologies

    Directory of Open Access Journals (Sweden)

    Manuela Baietto

    2009-06-01

    Full Text Available Electronic-nose devices have received considerable attention in the field of sensor technology during the past twenty years, largely due to the discovery of numerous applications derived from research in diverse fields of applied sciences. Recent applications of electronic nose technologies have come through advances in sensor design, material improvements, software innovations and progress in microcircuitry design and systems integration. The invention of many new e-nose sensor types and arrays, based on different detection principles and mechanisms, is closely correlated with the expansion of new applications. Electronic noses have provided a plethora of benefits to a variety of commercial industries, including the agricultural, biomedical, cosmetics, environmental, food, manufacturing, military, pharmaceutical, regulatory, and various scientific research fields. Advances have improved product attributes, uniformity, and consistency as a result of increases in quality control capabilities afforded by electronic-nose monitoring of all phases of industrial manufacturing processes. This paper is a review of the major electronic-nose technologies, developed since this specialized field was born and became prominent in the mid 1980s, and a summarization of some of the more important and useful applications that have been of greatest benefit to man.

  18. Smoothed Particle Hydrodynamics Model for Reactive Transport and Mineral Precipitation

    Energy Technology Data Exchange (ETDEWEB)

    Tartakovsky, Alexandre M.; Scheibe, Timothy D.; Redden, George; Meakin, Paul; Fang, Yilin

    2006-06-30

    A new Lagrangian particle model based on smoothed particle hydrodynamics was used to simulate pore scale precipitation reactions. The side-by-side injection of reacting solutions into two halves of a two-dimensional granular porous medium was simulated. Precipitation on grain surfaces occurred along a narrow zone in the middle of the domain, where the reacting solutes mixed to generate a supersaturated reaction product. The numerical simulations qualitatively reproduced the behavior observed in related laboratory experiments.

  19. Driven tracers in narrow channels

    Science.gov (United States)

    Cividini, J.; Mukamel, D.; Posch, H. A.

    2017-01-01

    Steady-state properties of a driven tracer moving in a narrow two-dimensional (2D) channel of quiescent medium are studied. The tracer drives the system out of equilibrium, perturbs the density and pressure fields, and gives the bath particles a nonzero average velocity, creating a current in the channel. Three models in which the confining effect of the channel is probed are analyzed and compared in this study: the first is the simple symmetric exclusion process (SSEP), for which the stationary density profile and the pressure on the walls in the frame of the tracer are computed. We show that the tracer acts like a dipolar source in an average velocity field. The spatial structure of this 2D strip is then simplified to a one-dimensional (1D) SSEP, in which exchanges of position between the tracer and the bath particles are allowed. Using a combination of mean-field theory and exact solution in the limit where no exchange is allowed gives good predictions of the velocity of the tracer and the density field. Finally, we show that results obtained for the 1D SSEP with exchanges also apply to a gas of overdamped hard disks in a narrow channel. The correspondence between the parameters of the SSEP and of the gas of hard disks is systematic and follows from simple intuitive arguments. Our analytical results are checked numerically.

  20. Spectral Narrowing in Semiconductor Microcavities

    Science.gov (United States)

    La Rocca, G. C.; Bassani, F.; Agranovich, V. M.

    1998-03-01

    The notion of in-plane motional narrowing of cavity polariton (CP) lines has been recently considered ( D.M. Whittaker et al.), Phys. Rev. Lett. 77, 4792 (1996); V. Savona et al.. Phys. Rev. Lett. 78, 4470 (1997). We point out that, in the presence of N>1 resonating quantum wells (QWs), the exciton component in a CP is coherently delocalized over all the individual QWs. Besides the two CP branches, also a dark exciton branch is present given by N-1 states similarly delocalized, but orthogonal to the cavity photon mode. If the QW disorder potential is weak compared to the Rabi splitting, it is seen by a CP as reduced by a factor 1/√N because of averaging along the cavity axis (G.C. La Rocca, F. Bassani, V.M. Agranovich, JOSA B 15), (1998). As for the in-plane motional narrowing, a simple scaling procedure shows that it would imply that the inhomogeneous linewidth of a CP be reduced by about four orders of magnitude compared to a QW exciton, which is incompatible with the experimental observations. The physical reason of such a shortcoming is that the disorder introduces localized exciton states which can resonantly scatter CPs, mixing them with states having a large k vector as well as with dark exciton states.

  1. From Nose to Brain: Un-Sensed Electrical Currents Applied in the Nose Alter Activity in Deep Brain Structures

    OpenAIRE

    Weiss, Tali; Shushan, Sagit; Ravia, Aharon; Hahamy, Avital; Secundo, Lavi; Weissbrod, Aharon; Ben-Yakov, Aya; Holtzman, Yael; Cohen-Atsmoni, Smadar; Roth, Yehudah; Sobel, Noam

    2016-01-01

    Rules linking patterns of olfactory receptor neuron activation in the nose to activity patterns in the brain and ensuing odor perception remain poorly understood. Artificially stimulating olfactory neurons with electrical currents and measuring ensuing perception may uncover these rules. We therefore inserted an electrode into the nose of 50 human volunteers and applied various currents for about an hour in each case. This induced assorted non-olfactory sensations but never once the perceptio...

  2. Separated flow past smooth slender bodies

    Science.gov (United States)

    Williams, Ann Louise

    1991-02-01

    This dissertation describes an investigation of the separated flow past slender bodies at high angles of attack. Flows of this type occur on aircraft and missile forebodies and can develop large forces which are important when considering stability and control of the vehicle. The objective of this work is to extend the vortex sheet model, which has previously been implemented for slender wings and circular and elliptic cones, to cones of more general cross-section and to non-conical bodies. The cross-sections of the bodies studied here are basically square or triangular, but with rounded corners. The model is inviscid, so the separation positions must be prescribed. Two distinct families of solutions have been identified. For laterally symmetric configurations with symmetric separation positions and no yaw, the first family solutions are symmetric, whereas the second family solutions are asymmetric. For elliptic cones, it is known that cross-section thickness affects the degree of asymmetry of the flow and this represents a mechanism for the control of side forces. Square or triangular cross-sections with rounded corners are of interest to aerodynamicists and have been investigated to assess the effect on asymmetry of making a circular cross-section 'square' or 'triangular'. For 'square' and 'triangular' cones placed either side, or corner on to the flow, results are obtained which enable the effect of cross-section shape on the degree of asymmetry to be assessed. A non-conical vortex sheet model has been developed for the first time for separation from a smooth body. Previously a non-conical line-vortex model was implemented, however lack of representation of vorticity near the separation line limits the applicability of the results. The solution procedure for the non-conical problem consists of a downstream-marching scheme starting from a known solution at the nose. Starting solutions are available if the flow at the nose is assumed conical. With symmetry

  3. Broad Diphotons from Narrow States

    CERN Document Server

    An, Haipeng; Zhang, Yue

    2015-01-01

    ATLAS and CMS have each reported a modest diphoton excess consistent with the decay of a broad resonance at ~ 750 GeV. We show how this signal can arise in a weakly coupled theory comprised solely of narrow width particles. In particular, if the decaying particle is produced off-shell, then the associated diphoton resonance will have a broad, adjustable width. We present simplified models which explain the diphoton excess through the three-body decay of a scalar or fermion. Our minimal ultraviolet completion is a weakly coupled and renormalizable theory of a singlet scalar plus a heavy vector-like quark and lepton. The smoking gun of this mechanism is an asymmetric diphoton peak recoiling against missing transverse energy, jets, or leptons.

  4. Classification of smooth Fano polytopes

    DEFF Research Database (Denmark)

    Øbro, Mikkel

    Fano polytopes up to isomorphism. A smooth Fano -polytope can have at most vertices. In case of vertices an explicit classification is known. The thesis contains the classification in case of vertices. Classifications of smooth Fano -polytopes for fixed exist only for . In the thesis an algorithm...... for the classification of smooth Fano -polytopes for any given is presented. The algorithm has been implemented and used to obtain the complete classification for .......A simplicial lattice polytope containing the origin in the interior is called a smooth Fano polytope, if the vertices of every facet is a basis of the lattice. The study of smooth Fano polytopes is motivated by their connection to toric varieties. The thesis concerns the classification of smooth...

  5. Cryogenic Detectors (Narrow Field Instruments)

    Science.gov (United States)

    Hoevers, H.; Verhoeve, P.

    Two cryogenic imaging spectrometer arrays are currently considered as focal plane instruments for XEUS. The narrow field imager 1 (NFI 1) will cover the energy range from 0.05 to 3 keV with an energy resolution of 2 eV, or better, at 500 eV. A second narrow field imager (NFI 2) covers the energy range from 1 to 15 keV with an energy resolution of 2 eV (at 1 keV) and 5 eV (at 7 keV), creating some overlap with part of the NFI 1 energy window. Both narrow field imagers have a 0.5 arcmin field of view. Their imaging capabilities are matched to the XEUS optics of 2 to 5 arcsec leading to 1 arcsec pixels. The detector arrays will be cooled by a closed cycle system comprising a mechanical cooler with a base temperature of 2.5 K and either a low temperature 3He sorption pump providing the very low temperature stage and/or an Adiabatic Demagnetization Refrigerator (ADR). The ADR cooler is explicitly needed to cool the NFI 2 array. The narrow field imager 1} Currently a 48 times 48 element array of superconducting tunnel junctions (STJ) is envisaged. Its operating temperature is in the range between 30 and 350 mK. Small, single Ta STJs (20-50 mum on a side) have shown 3.5 eV (FWHM) resolution at E = 525 eV and small arrays have been successfully demonstrated (6 times 6 pixels), or are currently tested (10 times 12 pixels). Alternatively, a prototype Distributed Read-Out Imaging Device (DROID), consisting of a linear superconducting Ta absorber of 20 times 100 mum2, including a 20 times 20 mum STJ for readout at either end, has shown a measured energy resolution of 2.4 eV (FWHM) at E = 500 eV. Simulations involving the diffusion properties as well as loss and tunnel rates have shown that the performance can be further improved by slight modifications in the geometry, and that the size of the DROIDS can be increased to 0.5-1.0 mm without loss in energy resolution. The relatively large areas and good energy resolution compared to single STJs make DROIDS good candidates for the

  6. 电子鼻技术%Introduction of Electronic Nose

    Institute of Scientific and Technical Information of China (English)

    关键; 张小丽

    2014-01-01

    Electronic nose ( e-nose) is an electronic system of bionic olfaction. The concept of electronic nose was formal y proposed in review articles published by Gardner in 1994. Electronic nose has been widely studied and applied in many areas, including food industry, tobacco industry, Chinese medicine industry, medical industry, environmental monitoring and military field, and been presented its unique characteristic nowadays. This paper introduces the concept, the working principle and applications of e-nose.%电子鼻是一种实现仿生嗅觉的电子系统,其概念由1994年发表的关于电子鼻的综述性文章中正式提出,目前在食品工业、烟草行业、中药行业、医学行业、环境监测、军事等领域都开展了研究和应用,并展现出了其独特的优点。文章介绍了电子鼻的相关概念、工作原理和应用现状。

  7. The "hot nose" sign on brain death nuclear scintigraphy: where does the flow really go?

    Science.gov (United States)

    Appelt, Eric A; Song, Won S; Phillips, William T; Metter, Darlene F; Salman, Umber A; Blumhardt, Ralph

    2008-01-01

    Nuclear scintigraphy has been used in patients with brain death since the 1970s. Many studies report a "hot nose" sign as predictive of brain death and lack of cerebral flow. Current nuclear medicine textbooks state that increased flow to the nose occurs secondary to occlusion of the internal carotid artery with flow rerouted to the nose via the external carotid artery. This explanation has been provided for decades assuming that the blood flow is actually increased to the nose. We performed a study to determine whether flow is really seen in the nose when a hot nose sign is present.

  8. Determination of authenticity of brand perfume using electronic nose prototypes

    Science.gov (United States)

    Gebicki, Jacek; Szulczynski, Bartosz; Kaminski, Marian

    2015-12-01

    The paper presents the practical application of an electronic nose technique for fast and efficient discrimination between authentic and fake perfume samples. Two self-built electronic nose prototypes equipped with a set of semiconductor sensors were employed for that purpose. Additionally 10 volunteers took part in the sensory analysis. The following perfumes and their fake counterparts were analysed: Dior—Fahrenheit, Eisenberg—J’ose, YSL—La nuit de L’homme, 7 Loewe and Spice Bomb. The investigations were carried out using the headspace of the aqueous solutions. Data analysis utilized multidimensional techniques: principle component analysis (PCA), linear discrimination analysis (LDA), k-nearest neighbour (k-NN). The results obtained confirmed the legitimacy of the electronic nose technique as an alternative to the sensory analysis as far as the determination of authenticity of perfume is concerned.

  9. Electronic Nose Based on an Optimized Competition Neural Network

    Directory of Open Access Journals (Sweden)

    Haiping Zhang

    2011-05-01

    Full Text Available In view of the fact that there are disadvantages in that the class number must be determined in advance, the value of learning rates are hard to fix, etc., when using traditional competitive neural networks (CNNs in electronic noses (E-noses, an optimized CNN method was presented. The optimized CNN was established on the basis of the optimum class number of samples according to the changes of the Davies and Bouldin (DB value and it could increase, divide, or delete neurons in order to adjust the number of neurons automatically. Moreover, the learning rate changes according to the variety of training times of each sample. The traditional CNN and the optimized CNN were applied to five kinds of sorted vinegars with an E-nose. The results showed that optimized network structures could adjust the number of clusters dynamically and resulted in good classifications.

  10. NDE Process Development Specification for SRB Composite Nose Cap

    Science.gov (United States)

    Suits, M.

    1999-01-01

    The Shuttle Upgrade program is a continuing improvement process to enable the Space Shuttle to be an effective space transportation vehicle for the next few decades. The Solid Rocket Booster (SRB), as a component of that system, is currently undergoing such an improvement. Advanced materials, such as composites, have given us a chance to improve performance and to reduce weight. The SRB Composite Nose Cap (CNC) program aims to replace the current aluminum nose cap, which is coated with a Thermal Protection System and poses a possible debris hazard, with a lighter, stronger, CNC. For the next 2 years, this program will evaluate the design, material selection, properties, and verification of the CNC. This particular process specification cites the methods and techniques for verifying the integrity of such a nose cap with nondestructive evaluation.

  11. [The crooked nose: correction of dorsal and caudal septal deviations].

    Science.gov (United States)

    Foda, H M T

    2010-09-01

    The deviated nose represents a complex cosmetic and functional problem. Septal surgery plays a central role in the successful management of the externally deviated nose. This study included 800 patients seeking rhinoplasty to correct external nasal deviations; 71% of these suffered from variable degrees of nasal obstruction. Septal surgery was necessary in 736 (92%) patients, not only to improve breathing, but also to achieve a straight, symmetric external nose. A graduated surgical approach was adopted to allow correction of the dorsal and caudal deviations of the nasal septum without weakening its structural support to the nasal dorsum or nasal tip. The approach depended on full mobilization of deviated cartilage, followed by straightening of the cartilage and its fixation in the corrected position by using bony splinting grafts through an external rhinoplasty approach.

  12. Electronic noses and their applications in environmental monitoring

    Energy Technology Data Exchange (ETDEWEB)

    Hashem, S.; Keller, P.E.; Kouzes, R.T.; Kangas, L.J. [Pacific Northwest Lab., Richland, WA (United States)

    1995-12-31

    Compact, portable systems capable of quickly identifying contaminants in the field are of great importance when monitoring the environment. In this paper, we examine the effectiveness of using artificial neural networks for real-time data analysis of a sensor array. Analyzing the sensor data in parallel may allow for rapid identification of contaminants in the field without requiring highly selective component sensors. A sensor array combined with a data analysis module is referred to as an electronic nose. In this paper, we investigate the trade off between sensor sensitivity and selectivity relating to the applications of neural network based-electronic noses in environmental monitoring. We use a prototype electronic nose which consists of nine tin-oxide Taguchi-type sensors, a temperature sensor, and a humidity sensor. We illustrate that by using neural network based analysis of a sensor data, the selectivity of a sensor array may be significantly improved, especially when some (or all) sensors are not highly selective.

  13. The Topological Effects of Smoothing.

    Science.gov (United States)

    Shafii, S; Dillard, S E; Hlawitschka, M; Hamann, B

    2012-01-01

    Scientific data sets generated by numerical simulations or experimental measurements often contain a substantial amount of noise. Smoothing the data removes noise but can have potentially drastic effects on the qualitative nature of the data, thereby influencing its characterization and visualization via topological analysis, for example. We propose a method to track topological changes throughout the smoothing process. As a preprocessing step, we oversmooth the data and collect a list of topological events, specifically the creation and destruction of extremal points. During rendering, it is possible to select the number of topological events by interactively manipulating a merging parameter. The result that a specific amount of smoothing has on the topology of the data is illustrated using a topology-derived transfer function that relates region connectivity of the smoothed data to the original regions of the unsmoothed data. This approach enables visual as well as quantitative analysis of the topological effects of smoothing.

  14. Conservative smoothing versus artificial viscosity

    Energy Technology Data Exchange (ETDEWEB)

    Guenther, C.; Hicks, D.L. [Michigan Technological Univ., Houghton, MI (United States); Swegle, J.W. [Sandia National Labs., Albuquerque, NM (United States). Solid and Structural Mechanics Dept.

    1994-08-01

    This report was stimulated by some recent investigations of S.P.H. (Smoothed Particle Hydrodynamics method). Solid dynamics computations with S.P.H. show symptoms of instabilities which are not eliminated by artificial viscosities. Both analysis and experiment indicate that conservative smoothing eliminates the instabilities in S.P.H. computations which artificial viscosities cannot. Questions were raised as to whether conservative smoothing might smear solutions more than artificial viscosity. Conservative smoothing, properly used, can produce more accurate solutions than the von Neumann-Richtmyer-Landshoff artificial viscosity which has been the standard for many years. The authors illustrate this using the vNR scheme on a test problem with known exact solution involving a shock collision in an ideal gas. They show that the norms of the errors with conservative smoothing are significantly smaller than the norms of the errors with artificial viscosity.

  15. Smoothness in Binomial Edge Ideals

    Directory of Open Access Journals (Sweden)

    Hamid Damadi

    2016-06-01

    Full Text Available In this paper we study some geometric properties of the algebraic set associated to the binomial edge ideal of a graph. We study the singularity and smoothness of the algebraic set associated to the binomial edge ideal of a graph. Some of these algebraic sets are irreducible and some of them are reducible. If every irreducible component of the algebraic set is smooth we call the graph an edge smooth graph, otherwise it is called an edge singular graph. We show that complete graphs are edge smooth and introduce two conditions such that the graph G is edge singular if and only if it satisfies these conditions. Then, it is shown that cycles and most of trees are edge singular. In addition, it is proved that complete bipartite graphs are edge smooth.

  16. High-Temperature Gas Sensor Array (Electronic Nose) Demonstrated

    Science.gov (United States)

    Hunter, Gary W.

    2002-01-01

    The ability to measure emissions from aeronautic engines and in commercial applications such as automotive emission control and chemical process monitoring is a necessary first step if one is going to actively control those emissions. One single sensor will not give all the information necessary to determine the chemical composition of a high-temperature, harsh environment. Rather, an array of gas sensor arrays--in effect, a high-temperature electronic "nose"--is necessary to characterize the chemical constituents of a diverse, high-temperature environment, such as an emissions stream. The signals produced by this nose could be analyzed to determine the constituents of the emission stream. Although commercial electronic noses for near-room temperature applications exist, they often depend significantly on lower temperature materials or only one sensor type. A separate development effort necessary for a high-temperature electronic nose is being undertaken by the NASA Glenn Research Center, Case Western Reserve University, Ohio State University, and Makel Engineering, Inc. The sensors are specially designed for hightemperature environments. A first-generation high-temperature electronic nose has been demonstrated on a modified automotive engine. This nose sensor array was composed of sensors designed for hightemperature environments fabricated using microelectromechanical-systems- (MEMS-) based technology. The array included a tin-oxide-based sensor doped for nitrogen oxide (NOx) sensitivity, a SiC-based hydrocarbon (CxHy) sensor, and an oxygen sensor (O2). These sensors operate on different principles--resistor, diode, and electrochemical cell, respectively--and each sensor has very different responses to the individual gases in the environment. A picture showing the sensor head for the array is shown in the photograph on the left and the sensors installed in the engine are shown in the photograph on the right. Electronics are interfaced with the sensors for

  17. Necrotizing Fasciitis of the Nose Complicated with Cavernous Sinus Thrombosis

    Directory of Open Access Journals (Sweden)

    D. Swaminath

    2014-01-01

    Full Text Available Necrotizing fasciitis is a rapidly progressive life threatening bacterial infection of the skin, the subcutaneous tissue, and the fascia. We present a case of necrotizing fasciitis involving the nose complicated by cavernous sinus thrombosis. Few cases of septic cavernous sinus thrombosis have been reported to be caused by cellulitis of the face but necrotizing fasciitis of the nose is rare. It is very important to recognize the early signs of cavernous thrombosis. Treatment for septic cavernous sinus thrombosis is controversial but early use of empirical antibiotics is imperative.

  18. Fiber optical artificial nose for the food industry

    Science.gov (United States)

    Mahmoud, Mohamed

    2003-04-01

    An artificial nose has been attractive for scientific research and the food industry. This paper proposes that the detection and recognition of odours or chemicals concentrate can be achieved by means of passive and compact size fiber optic sensors (Fiber Bragg Gratings Technology) that will form an olfactory sensor array and a fuzzy logic algorithm that will form the recognition artificial intelligence. The mathematical model of the fiber Bragg gratings olfactory sensor is developed and the design model of the artificial fiber optic nose is introduced.

  19. Angioendotheliosarcoma of the nose--a case report

    DEFF Research Database (Denmark)

    Waersted, A; Andersen, Klaus Ejner; Hansen, J P

    1984-01-01

    Angioendotheliosarcoma of the face or scalp is regarded as a highly malignant tumor. We present a case with onset as a purple macule on the nose, suspected to be rosacea, and emphasize the use of early skin biopsy when a red or purple discoloration is seen in the face of elderly people.......Angioendotheliosarcoma of the face or scalp is regarded as a highly malignant tumor. We present a case with onset as a purple macule on the nose, suspected to be rosacea, and emphasize the use of early skin biopsy when a red or purple discoloration is seen in the face of elderly people....

  20. Anger perceptually and conceptually narrows cognitive scope.

    Science.gov (United States)

    Gable, Philip A; Poole, Bryan D; Harmon-Jones, Eddie

    2015-07-01

    For the last 50 years, research investigating the effect of emotions on scope of cognitive processing was based on models proposing that affective valence determined cognitive scope. More recently, our motivational intensity model suggests that this past work had confounded valence with motivational intensity. Research derived from this model supports the idea that motivational intensity, rather than affective valence, explains much of the variance emotions have on cognitive scope. However, the motivational intensity model is limited in that the empirical work has examined only positive affects high in approach and negative affects high in avoidance motivation. Thus, perhaps only approach-positive and avoidance-negative states narrow cognitive scope. The present research was designed to clarify these conceptual issues by examining the effect of anger, a negatively valenced approach-motivated state, on cognitive scope. Results revealed that anger narrowed attentional scope relative to a neutral state and that attentional narrowing to anger was similar to the attentional narrowing caused by high approach-motivated positive affects (Study 1). This narrowing of attention was related to trait approach motivation (Studies 2 and Study 3). Anger also narrowed conceptual cognitive categorization (Study 4). Narrowing of categorization related to participants' approach motivation toward anger stimuli. Together, these results suggest that anger, an approach-motivated negative affect, narrows perceptual and conceptual cognitive scope. More broadly, these results support the conceptual model that motivational intensity per se, rather than approach-positive and avoidance-negative states, causes a narrowing of cognitive scope.

  1. From Nose to Brain: Un-Sensed Electrical Currents Applied in the Nose Alter Activity in Deep Brain Structures.

    Science.gov (United States)

    Weiss, Tali; Shushan, Sagit; Ravia, Aharon; Hahamy, Avital; Secundo, Lavi; Weissbrod, Aharon; Ben-Yakov, Aya; Holtzman, Yael; Cohen-Atsmoni, Smadar; Roth, Yehudah; Sobel, Noam

    2016-09-02

    Rules linking patterns of olfactory receptor neuron activation in the nose to activity patterns in the brain and ensuing odor perception remain poorly understood. Artificially stimulating olfactory neurons with electrical currents and measuring ensuing perception may uncover these rules. We therefore inserted an electrode into the nose of 50 human volunteers and applied various currents for about an hour in each case. This induced assorted non-olfactory sensations but never once the perception of odor. To validate contact with the olfactory path, we used functional magnetic resonance imaging to measure resting-state brain activity in 18 subjects before and after un-sensed stimulation. We observed stimulation-induced neural decorrelation specifically in primary olfactory cortex, implying contact with the olfactory path. These results suggest that indiscriminate olfactory activation does not equate with odor perception. Moreover, this effort serendipitously uncovered a novel path for minimally invasive brain stimulation through the nose.

  2. Smooth analysis in Banach spaces

    CERN Document Server

    Hájek, Petr

    2014-01-01

    This bookis aboutthe subject of higher smoothness in separable real Banach spaces.It brings together several angles of view on polynomials, both in finite and infinite setting.Also a rather thorough and systematic view of the more recent results, and the authors work is given. The book revolves around two main broad questions: What is the best smoothness of a given Banach space, and its structural consequences? How large is a supply of smooth functions in the sense of approximating continuous functions in the uniform topology, i.e. how does the Stone-Weierstrass theorem generalize into in

  3. 14 CFR 23.499 - Supplementary conditions for nose wheels.

    Science.gov (United States)

    2010-01-01

    ..., the application of 1.33 times the full steering torque combined with a vertical reaction equal to 1.33 times the maximum static reaction on the nose gear must be assumed. However, if a torque limiting device is installed, the steering torque can be reduced to the maximum value allowed by that device. (e)...

  4. Toward a minituarized low-power micromechanical electronic nose

    NARCIS (Netherlands)

    Karabaçak, D.; Sieben-Xu, L.; Vandecasteele, M.; Andel, Y. van; Wouters, D.; Calama, M.C.; Brongersma, S.H.

    2012-01-01

    An electronic nose based on an array of vibrating doubly clamped beams is proposed. These very high aspect ratio (length/thickness) suspended resonators can be individually functionalized by applying polymer coatings with an inkjet printing approach. The absorption of volatile compounds induces a sw

  5. Electronic Nose as an NDT Tool for Aerospace Industry

    Science.gov (United States)

    De Vito, Saverio; Massera, Ettore; Miglietta, Mara; Fattoruso, Grazia; Di Francia, Girolamo

    Artificial olfaction is an emerging technology aiming to develop tools for easy, rapid and mobile gas mixture analysis. So far, its application to several application fields is under investigation with some commercial solution already deployed. In this work we present the results of the development process for an electronic nose devised for NDT in aerospace industry focusing on its pattern recognition stage.

  6. Using Electronic Noses to Detect Tumors During Neurosurgery

    Science.gov (United States)

    Homer, Margie L.; Ryan, Margaret A.; Lara, Liana M.; Kateb, Babak; Chen, Mike

    2008-01-01

    It has been proposed to develop special-purpose electronic noses and algorithms for processing the digitized outputs of the electronic noses for determining whether tissue exposed during neurosurgery is cancerous. At present, visual inspection by a surgeon is the only available intraoperative technique for detecting cancerous tissue. Implementation of the proposal would help to satisfy a desire, expressed by some neurosurgeons, for an intraoperative technique for determining whether all of a brain tumor has been removed. The electronic-nose technique could complement multimodal imaging techniques, which have also been proposed as means of detecting cancerous tissue. There are also other potential applications of the electronic-nose technique in general diagnosis of abnormal tissue. In preliminary experiments performed to assess the viability of the proposal, the problem of distinguishing between different types of cultured cells was substituted for the problem of distinguishing between normal and abnormal specimens of the same type of tissue. The figure presents data from one experiment, illustrating differences between patterns that could be used to distinguish between two types of cultured cancer cells. Further development can be expected to include studies directed toward answering questions concerning not only the possibility of distinguishing among various types of normal and abnormal tissue but also distinguishing between tissues of interest and other odorous substances that may be present in medical settings.

  7. The nose in children with unilateral cleft lip and palate

    NARCIS (Netherlands)

    C.D.A. Verwoerd (Carel); R. Mladina (R.); G.J. Nolst-Trenité (Gilbert J.); R.W. Pigott (R.)

    1995-01-01

    textabstractSurgeons and orthodontists are still challenged to achieve ‘better’ noses for children with a unilateral cleft or lip, alveolus and palate (UCLP). Various aspects are discussed: infant anatomy and later changes, developmental mechanics, cleft syndrome in animals with surgically produced

  8. File list: ALL.Emb.50.AllAg.Embryonic_nose [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available ALL.Emb.50.AllAg.Embryonic_nose mm9 All antigens Embryo Embryonic nose SRX1035119,S...RX1035120 http://dbarchive.biosciencedbc.jp/kyushu-u/mm9/assembled/ALL.Emb.50.AllAg.Embryonic_nose.bed ...

  9. File list: Oth.Emb.20.AllAg.Embryonic_nose [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available Oth.Emb.20.AllAg.Embryonic_nose mm9 TFs and others Embryo Embryonic nose SRX1035119... http://dbarchive.biosciencedbc.jp/kyushu-u/mm9/assembled/Oth.Emb.20.AllAg.Embryonic_nose.bed ...

  10. File list: Oth.Emb.05.AllAg.Embryonic_nose [Chip-atlas[Archive

    Lifescience Database Archive (English)

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  11. File list: Unc.Emb.50.AllAg.Embryonic_nose [Chip-atlas[Archive

    Lifescience Database Archive (English)

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  12. File list: ALL.Emb.20.AllAg.Embryonic_nose [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available ALL.Emb.20.AllAg.Embryonic_nose mm9 All antigens Embryo Embryonic nose SRX1035119,S...RX1035120 http://dbarchive.biosciencedbc.jp/kyushu-u/mm9/assembled/ALL.Emb.20.AllAg.Embryonic_nose.bed ...

  13. File list: ALL.Emb.05.AllAg.Embryonic_nose [Chip-atlas[Archive

    Lifescience Database Archive (English)

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  14. File list: Oth.Emb.50.AllAg.Embryonic_nose [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available Oth.Emb.50.AllAg.Embryonic_nose mm9 TFs and others Embryo Embryonic nose SRX1035119... http://dbarchive.biosciencedbc.jp/kyushu-u/mm9/assembled/Oth.Emb.50.AllAg.Embryonic_nose.bed ...

  15. File list: Unc.Emb.20.AllAg.Embryonic_nose [Chip-atlas[Archive

    Lifescience Database Archive (English)

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  16. File list: Unc.Emb.10.AllAg.Embryonic_nose [Chip-atlas[Archive

    Lifescience Database Archive (English)

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  17. File list: Oth.Emb.10.AllAg.Embryonic_nose [Chip-atlas[Archive

    Lifescience Database Archive (English)

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  18. File list: Unc.Emb.05.AllAg.Embryonic_nose [Chip-atlas[Archive

    Lifescience Database Archive (English)

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  19. File list: ALL.Emb.10.AllAg.Embryonic_nose [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available ALL.Emb.10.AllAg.Embryonic_nose mm9 All antigens Embryo Embryonic nose SRX1035119,S...RX1035120 http://dbarchive.biosciencedbc.jp/kyushu-u/mm9/assembled/ALL.Emb.10.AllAg.Embryonic_nose.bed ...

  20. 21 CFR 874.4500 - Ear, nose, and throat microsurgical carbon dioxide laser.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Ear, nose, and throat microsurgical carbon dioxide..., nose, and throat microsurgical carbon dioxide laser. (a) Identification. An ear, nose, and throat microsurgical carbon dioxide laser is a device intended for the surgical excision of tissue from the ear,...

  1. SMOOTHING BY CONVEX QUADRATIC PROGRAMMING

    Institute of Scientific and Technical Information of China (English)

    Bing-sheng He; Yu-mei Wang

    2005-01-01

    In this paper, we study the relaxed smoothing problems with general closed convex constraints. It is pointed out that such problems can be converted to a convex quadratic minimization problem for which there are good programs in software libraries.

  2. Wetting on smooth micropatterned defects

    OpenAIRE

    Debuisson, Damien; Dufour, Renaud; Senez, Vincent; Arscott, Steve

    2011-01-01

    We develop a model which predicts the contact angle hysteresis introduced by smooth micropatterned defects. The defects are modeled by a smooth function and the contact angle hysteresis is explained using a tangent line solution. When the liquid micro-meniscus touches both sides of the defect simultaneously, depinning of the contact line occurs. The defects are fabricated using a photoresist and experimental results confirm the model. An important point is that the model is scale-independent,...

  3. Caudal Septal Stabilization Suturing Technique to Treat Crooked Noses.

    Science.gov (United States)

    Baykal, Bahadir; Erdim, Ibrahim; Guvey, Ali; Oghan, Fatih; Kayhan, Fatma Tulin

    2016-10-01

    To rotate the nasal axis and septum to the midline using an L-strut graft and a novel caudal septal stabilization suturing technique to treat crooked noses. Thirty-six patients were included in the study. First, an L-strut graft was prepared by excising the deviated cartilage site in all patients. Second, multiple stabilization suturing, which we describe as a caudal septal stabilization suturing technique with a "fishing net"-like appearance, was applied between the anterior nasal spine and caudal septum in all patients. This new surgical technique, used to rotate the caudal septum, was applied to 22 I-type and 14 C-type crooked noses. Correction rates for the crooked noses were compared between the 2 inclination types with angular estimations. Deviation angles were measured using the AutoCAD 2012 software package and frontal (anterior) views, with the Frankfurt horizontal line parallel to the ground. Nasal axis angles showing angle improvement graded 4 categories as excellent, good, acceptable, and unsuccessful for evaluations at 6 months after surgery in the study. The success rate in the C-type nasal inclination was 86.7% (±21.9) and 88% (±16.7) in the I-type. The overall success rate of L-strut grafting and caudal septal stabilization suturing in crooked nose surgeries was 87.5% (±18.6). "Unsuccessful" results were not reported in any of the patients. L-strut grafting and caudal septal stabilization suturing techniques are efficacious in crooked noses according to objective measurement analysis results. However, a longer follow-up duration in a larger patient population is needed.

  4. Exotic smoothness and quantum gravity

    Energy Technology Data Exchange (ETDEWEB)

    Asselmeyer-Maluga, T, E-mail: torsten.asselmeyer-maluga@dlr.d [German Aerospace Center, Berlin, Germany and Loyola University, New Orleans, LA (United States)

    2010-08-21

    Since the first work on exotic smoothness in physics, it was folklore to assume a direct influence of exotic smoothness to quantum gravity. Thus, the negative result of Duston (2009 arXiv:0911.4068) was a surprise. A closer look into the semi-classical approach uncovered the implicit assumption of a close connection between geometry and smoothness structure. But both structures, geometry and smoothness, are independent of each other. In this paper we calculate the 'smoothness structure' part of the path integral in quantum gravity assuming that the 'sum over geometries' is already given. For that purpose we use the knot surgery of Fintushel and Stern applied to the class E(n) of elliptic surfaces. We mainly focus our attention to the K3 surfaces E(2). Then we assume that every exotic smoothness structure of the K3 surface can be generated by knot or link surgery in the manner of Fintushel and Stern. The results are applied to the calculation of expectation values. Here we discuss the two observables, volume and Wilson loop, for the construction of an exotic 4-manifold using the knot 5{sub 2} and the Whitehead link Wh. By using Mostow rigidity, we obtain a topological contribution to the expectation value of the volume. Furthermore, we obtain a justification of area quantization.

  5. Exotic Smoothness and Quantum Gravity

    CERN Document Server

    Asselmeyer-Maluga, Torsten

    2010-01-01

    Since the first work on exotic smoothness in physics, it was folklore to assume a direct influence of exotic smoothness to quantum gravity. Thus, the negative result of Duston (arXiv:0911.4068) was a surprise. A closer look into the semi-classical approach uncovered the implicit assumption of a close connection between geometry and smoothness structure. But both structures, geometry and smoothness, are independent of each other. In this paper we calculate the "smoothness structure" part of the path integral in quantum gravity assuming that the "sum over geometries" is already given. For that purpose we use the knot surgery of Fintushel and Stern applied to the class E(n) of elliptic surfaces. We mainly focus our attention to the K3 surfaces E(2). Then we assume that every exotic smoothness structure of the K3 surface can be generated by knot or link surgery a la Fintushel and Stern. The results are applied to the calculation of expectation values. Here we discuss the two observables, volume and Wilson loop, f...

  6. Glucocorticosteroids and beta(2)-Adrenoceptor Agonists Synergize to Inhibit Airway Smooth Muscle Remodeling

    NARCIS (Netherlands)

    Dekkers, Bart G. J.; Pehlic, Adnan; Mariani, Raissa; Bos, I. Sophie T.; Meurs, Herman; Zaagsma, Johan

    2012-01-01

    Airway remodeling, including increased airway smooth muscle (ASM) mass and contractility, contributes to increased airway narrowing in asthma. Increased ASM mass may be caused by exposure to mitogens, including platelet-derived growth factor (PDGF) and collagen type I, which induce a proliferative,

  7. Smooth quantum gravity: Exotic smoothness and Quantum gravity

    CERN Document Server

    Asselmeyer-Maluga, Torsten

    2016-01-01

    Over the last two decades, many unexpected relations between exotic smoothness, e.g. exotic $\\mathbb{R}^{4}$, and quantum field theory were found. Some of these relations are rooted in a relation to superstring theory and quantum gravity. Therefore one would expect that exotic smoothness is directly related to the quantization of general relativity. In this article we will support this conjecture and develop a new approach to quantum gravity called \\emph{smooth quantum gravity} by using smooth 4-manifolds with an exotic smoothness structure. In particular we discuss the appearance of a wildly embedded 3-manifold which we identify with a quantum state. Furthermore, we analyze this quantum state by using foliation theory and relate it to an element in an operator algebra. Then we describe a set of geometric, non-commutative operators, the skein algebra, which can be used to determine the geometry of a 3-manifold. This operator algebra can be understood as a deformation quantization of the classical Poisson alge...

  8. Social learning solves the problem of narrow-peaked search landscapes: experimental evidence in humans.

    Science.gov (United States)

    Acerbi, Alberto; Tennie, Claudio; Mesoudi, Alex

    2016-09-01

    The extensive use of social learning is considered a major reason for the ecological success of humans. Theoretical considerations, models and experiments have explored the evolutionary basis of social learning, showing the conditions under which learning from others is more adaptive than individual learning. Here we present an extension of a previous experimental set-up, in which individuals go on simulated 'hunts' and their success depends on the features of a 'virtual arrowhead' they design. Individuals can modify their arrowhead either by individual trial and error or by copying others. We study how, in a multimodal adaptive landscape, the smoothness of the peaks influences learning. We compare narrow peaks, in which solutions close to optima do not provide useful feedback to individuals, to wide peaks, where smooth landscapes allow an effective hill-climbing individual learning strategy. We show that individual learning is more difficult in narrow-peaked landscapes, but that social learners perform almost equally well in both narrow- and wide-peaked search spaces. There was a weak trend for more copying in the narrow than wide condition, although as in previous experiments social information was generally underutilized. Our results highlight the importance of tasks' design space when studying the adaptiveness of high-fidelity social learning.

  9. A Narrow View of Reading Promotes Comprehension

    National Research Council Canada - National Science Library

    Alan G Kamhi

    2007-01-01

      In sum, embracing the narrow view of reading will promote differentiated assessment of reading and content-specific knowledge that will not only eliminate the reading crisis, but also focus attention...

  10. Device Physics of Narrow Gap Semiconductors

    CERN Document Server

    Chu, Junhao

    2010-01-01

    Narrow gap semiconductors obey the general rules of semiconductor science, but often exhibit extreme features of these rules because of the same properties that produce their narrow gaps. Consequently these materials provide sensitive tests of theory, and the opportunity for the design of innovative devices. Narrow gap semiconductors are the most important materials for the preparation of advanced modern infrared systems. Device Physics of Narrow Gap Semiconductors offers descriptions of the materials science and device physics of these unique materials. Topics covered include impurities and defects, recombination mechanisms, surface and interface properties, and the properties of low dimensional systems for infrared applications. This book will help readers to understand not only the semiconductor physics and materials science, but also how they relate to advanced opto-electronic devices. The last chapter applies the understanding of device physics to photoconductive detectors, photovoltaic infrared detector...

  11. Narrow deeply bound K- atomic states

    Science.gov (United States)

    Friedman, E.; Gal, A.

    1999-07-01

    Using optical potentials fitted to a comprehensive set of strong interaction level shifts and widths in K- atoms, we predict that the K- atomic levels which are inaccessible in the atomic cascade process are generally narrow, spanning a range of widths about 50-1500 keV over the entire periodic table. The mechanism for this narrowing is different from the mechanism for narrowing of pionic atom levels. Examples of such `deeply bound' K- atomic states are given, showing that in many cases these states should be reasonably well resolved. Several reactions which could be used to form these `deeply bound' states are mentioned. Narrow deeply bound states are expected also in overlinep atoms.

  12. Narrow linewidth pulsed optical parametric oscillator

    Indian Academy of Sciences (India)

    S Das

    2010-11-01

    Tunable narrow linewidth radiation by optical parametric oscillation has many applications, particularly in spectroscopic investigation. In this paper, different techniques such as injection seeding, use of spectral selecting element like grating, grating and etalon in combination, grazing angle of incidence, entangled cavity configuration and type-II phase matching have been discussed for generating tunable narrow linewidth radiation by singly resonant optical parametric oscillation process.

  13. Selective Smoothed Finite Element Method

    Institute of Scientific and Technical Information of China (English)

    2007-01-01

    The paper examines three selective schemes for the smoothed finite element method (SFEM) which was formulated by incorporating a cell-wise strain smoothing operation into the standard compatible finite element method (FEM). These selective SFEM schemes were formulated based on three selective integration FEM schemes with similar properties found between the number of smoothing cells in the SFEM and the number of Gaussian integration points in the FEM. Both scheme 1 and scheme 2 are free of nearly incompressible locking, but scheme 2 is more general and gives better results than scheme 1. In addition, scheme 2 can be applied to anisotropic and nonlinear situations, while scheme 1 can only be applied to isotropic and linear situations. Scheme 3 is free of shear locking. This scheme can be applied to plate and shell problems. Results of the numerical study show that the selective SFEM schemes give more accurate results than the FEM schemes.

  14. α-compactness in smooth topological spaces

    Directory of Open Access Journals (Sweden)

    Chun-Kee Park

    2003-01-01

    Full Text Available We introduce the concepts of smooth α-closure and smooth α-interior of a fuzzy set which are generalizations of smooth closure and smooth interior of a fuzzy set defined by Demirci (1997 and obtain some of their structural properties.

  15. Electrolyte depletion in white-nose syndrome bats

    Science.gov (United States)

    Cryan, Paul M.; Meteyer, Carol Uphoff; Blehert, David S.; Lorch, Jeffrey M.; Reeder, DeeAnn M.; Turner, Gregory G.; Webb, Julie; Behr, Melissa; Verant, Michelle L.; Russell, Robin E.; Castle, Kevin T.

    2013-01-01

    The emerging wildlife disease white-nose syndrome is causing widespread mortality in hibernating North American bats. White-nose syndrome occurs when the fungus Geomyces destructans infects the living skin of bats during hibernation, but links between infection and mortality are underexplored. We analyzed blood from hibernating bats and compared blood electrolyte levels to wing damage caused by the fungus. Sodium and chloride tended to decrease as wing damage increased in severity. Depletion of these electrolytes suggests that infected bats may become hypotonically dehydrated during winter. Although bats regularly arouse from hibernation to drink during winter, water available in hibernacula may not contain sufficient electrolytes to offset winter losses caused by disease. Damage to bat wings from G. destructans may cause life-threatening electrolyte imbalances.

  16. Novel materials and applications of electronic noses and tongues.

    Science.gov (United States)

    Gouma, Perena; Sberveglieri, Giorgio

    2004-10-01

    This introductory article describes the content of the October 2004 issue of MRS Bulletin focusing on novel materials and applications of electronic noses and tongues. The articles in this issue review the state of the art in materials, devices, and data processing algorithms used in electronic olfaction and taste systems. The most common gas- and liquid-phase analyte detection tools are presented and compared with traditional chemical analysis instrumentation such as gas chromatography/mass spectroscopy systems. Metal oxides, polymer/polymer composites, and dyes are covered in these articles as key sensing materials. Resistive, optical, electrochemical, and other types of electronic nose and tongue systems are reviewed, and their use in diverse applications, including environmental and food-quality monitoring and medical diagnostics, is discussed.

  17. AN UNUSUAL FOREIGN BODY IN THE NOSE: DIFFICULTY IN DIAGNOSIS

    Directory of Open Access Journals (Sweden)

    Shankar

    2015-08-01

    Full Text Available Foreign bodies in the nose are usually found in children between 2 - 5years of age, the intellectually impaired and psychiatric patients . (1 When mineral salts are deposited on a long retained foreign body, the object is called a rhinolith. Common objects p ushed in to the nose are paper, beads, beans, seeds, nuts and button batteries. Nasal foreign bodies can sometimes be removed in the OPD with a nasal speculum and Hartmann nasal forceps, usually general anesthesia is necessary if the foreign body placed mo re deeply in the nasal cavity or if a rhinolith has formed. Here we are presenting a case of open safety pin in the (R nasal cavity with difficulty in diagnosis, removed by endoscopic approach.

  18. Olfactory perception, communication, and the nose-to-brain pathway.

    Science.gov (United States)

    Stockhorst, Ursula; Pietrowsky, Reinhard

    2004-10-30

    The present paper's aim is of to give an overview about the basic knowledge as well as actual topics of olfaction--with a special regard on behavior. We summarize different functions of the nose and the olfactory system in human physiology and psychology. We will first describe the functional anatomy of the olfactory system in man. Afterwards, the function of the olfactory system will be viewed from an evolutionary and phylogenetic perspective. We will further outline the main features of olfactory perception, and will show how olfactory perception is influenced by learning. Olfactory signals are relevant stimuli that affect communication. Consequently, the role of the olfactory system in social interaction and mood will be described and gender differences will be addressed. Finally, the function of the nose as an interface to the brain, including implications for pharmacology, will be discussed.

  19. Differentiation of closely related fungi by electronic nose analysis

    DEFF Research Database (Denmark)

    Karlshøj, Kristian; Nielsen, Per Væggemose; Larsen, Thomas Ostenfeld

    2007-01-01

    In this work the potential of electronic nose analysis for differentiation of closely related fun has been described. A total of 20 isolates of the cheese-associated species Geotrichum candidum, Penicillium camemberti, P.nordicum, and Proqueford and its closely related species P paneum, P carneum...... as well as the noacheese ociated P. expansum have been investigated by electronic nose, GC-MS, and LGMS analysis. The isolates were inoculated on yeast extract sucroseagar in 20-mL headspace flasks and electronicnose analysis was performed daily for a-74period. To assess which volatile metabolites...... by high pressure liquid chromatography, coupled-to a diode array detector and a time of flight mass spectrometer. Several mycotoxins were detected in samples from the specles P.nordicum, P.roqueforti, P.paneum, P.carneum, and P.expansum. Differentiation of closely related mycotoxin producing fungi...

  20. A Novel Medical E-Nose Signal Analysis System

    Directory of Open Access Journals (Sweden)

    Lu Kou

    2017-04-01

    Full Text Available It has been proven that certain biomarkers in people’s breath have a relationship with diseases and blood glucose levels (BGLs. As a result, it is possible to detect diseases and predict BGLs by analysis of breath samples captured by e-noses. In this paper, a novel optimized medical e-nose system specified for disease diagnosis and BGL prediction is proposed. A large-scale breath dataset has been collected using the proposed system. Experiments have been organized on the collected dataset and the experimental results have shown that the proposed system can well solve the problems of existing systems. The methods have effectively improved the classification accuracy.

  1. Tentative Identification of Interstellar Dust in Heliosphere Nose

    CERN Document Server

    Frisch, P C

    2005-01-01

    Observations of polarization toward nearby stars in the upwind direction made by (Tinbergen, 1982) are consistent with an origin associated with interstellar dust grains entrained in interstellar magnetic fields wrapped around the heliosphere nose. The region of maximum polarization is centered around ecliptic coordinates (295 deg,0 deg). The direction of maximum polarization is offset along the ecliptic longitude by about 35 deg from the heliosphere nose. An offset is also seen between the region with the best aligned dust grains (ecliptic longitudes 281 deg to 330 deg) and inflowing interstellar dust grains observed by Ulysses and Galileo, and in this region polarization strength anti-correlates with ecliptic latitude. These offsets support an interpretation whereby the maximum polarization occurs in a direction perpendicular to the interstellar field lines, the region of consistent polarization angle shows the deflection of small grains, and the inflow of larger grains shows the undeflected grain populatio...

  2. Olfactory Mucosa Tissue Based Biosensor for Bioelectronic Nose

    Science.gov (United States)

    Liu, Qingjun; Ye, Weiwei; Yu, Hui; Hu, Ning; Cai, Hua; Wang, Ping

    2009-05-01

    Biological olfactory system can distinguish thousands of odors. In order to realize the biomimetic design of electronic nose on the principle of mammalian olfactory system, we have reported bioelectronic nose based on cultured olfactory cells. In this study, the electrical property of the tissue-semiconductor interface was analyzed by the volume conductor theory and the sheet conductor model. Olfactory mucosa tissue of rat was isolated and fixed on the surface of the light-addressable potentiometric sensor (LAPS), with the natural stations of the neuronal populations and functional receptor unit of the cilia well reserved. By the extracellular potentials of the olfactory receptor cells of the mucosa tissue monitored, both the simulation and the experimental results suggested that this tissue-semiconductor hybrid system was sensitive to odorants stimulation.

  3. Present and potential distribution of Snub-nosed Monkey

    DEFF Research Database (Denmark)

    Nüchel, Jonas; Bøcher, Peder Klith; Svenning, Jens-Christian

    are the Snub-nosed Monkeys (Rhinopithecus), a temperate-subtropical East Asian genus. We use species distribution modeling to assess the following question of key relevancy for conservation management of Rhinopithecus; 1. Which climatic factors determine the present distribution of Rhinopithecus within...... distribution of Rhinopithecus within the region, considering climate, habitat availability and the locations of nature reserves. Keywords: biodiversity, biogeography, conservation, China, snub-nosed monkey, rhinopithecus, primates, species distribution modeling......Around 28 % of mammal species are threatened or near threatened with extinction. One of the mammal taxa with many threatened species are the primates. Of which more than 65 % of the world’s 424 know species are threatened or near threatened (IUCN, 2014). One group of threatened primates...

  4. A historical vignette (15). "Be proud of yourself: you have a history!" The nose and the plague.

    Science.gov (United States)

    Tainmont, J

    2009-01-01

    The nose and the plague. Although the plague does not cause any specific nasal pathology, the miasma theory and the repulsive smell of the disease were factors that contributed to a strong emphasis on the nose. To stop the spread of the disease, it was thought necessary to saturate the nose with protective scents (hence the nose of the plague doctors) (Figure 1), or simply to hold one's nose. Moreover, the nose was long considered to be an outlet for mucus from the encephalon, and so induced nose bleeding and sneezing were advised when the plague seemed to be attacking the brain.

  5. Wetting on smooth micropatterned defects

    CERN Document Server

    Debuisson, Damien; Senez, Vincent; Arscott, Steve

    2011-01-01

    We develop a model which predicts the contact angle hysteresis introduced by smooth micropatterned defects. The defects are modeled by a smooth function and the contact angle hysteresis is explained using a tangent line solution. When the liquid micro-meniscus touches both sides of the defect simultaneously, depinning of the contact line occurs. The defects are fabricated using a photoresist and experimental results confirm the model. An important point is that the model is scale-independent, i.e. the contact angle hysteresis is dependent on the aspect ratio of the function, not on its absolute size; this could have implications for natural surface defects.

  6. Tour of a labyrinth: exploring the vertebrate nose.

    Science.gov (United States)

    Van Valkenburgh, Blaire; Smith, Timothy D; Craven, Brent A

    2014-11-01

    This special issue of The Anatomical Record is the outcome of a symposium entitled "Inside the Vertebrate Nose: Evolution, Structure and Function." The skeletal framework of the nasal cavity is a complicated structure that often houses sinuses and comprises an internal skeleton of bone or cartilage that can vary greatly in architecture among species. The nose serves multiple functions, including olfaction and respiratory air-conditioning, and its morphology is constrained by evolution, development, and conflicting demands on cranial space, such as enlarged orbits. The nasal cavity of vertebrates has received much more attention in the last decade due to the emergence of nondestructive methods that allow improved visualization of the internal anatomy of the skull, such as high-resolution x-ray computed tomography and magnetic resonance imaging. The 17 articles included here represent a broad range of investigators, from paleontologists to engineers, who approach the nose from different perspectives. Key topics include the evolution and development of the nose, its comparative anatomy and function, and airflow through the nasal cavity of individual species. In addition, this special issue includes review articles on anatomical reduction of the olfactory apparatus in both cetaceans and primates (the vomeronasal system), as well as the molecular biology of olfaction in vertebrates. Together these articles provide an expansive summary of our current understanding of vertebrate nasal anatomy and function. In this introduction, we provide background information and an overview of each of the three primary topics, and place each article within the context of previous research and the major challenges that lie ahead.

  7. ["Clown nose"--skin metastasis of breast cancer].

    Science.gov (United States)

    Soyer, H P; Cerroni, L; Smolle, J; Kerl, H

    1990-10-01

    We report on a 74-year-old woman showing a reddish infiltration of the tip of the nose, which had appeared 3 months ago. Clinically, we considered the following differential diagnoses: sarcoidosis, rosacea, pseudolymphoma, and metastasis. Histological and immunohistological investigation proved a cutaneous metastasis of carcinoma of the breast. Our case report gives evidence of the fact that cutaneous metastases of systemic malignancies are frequently located in acral regions of the skin.

  8. Electronic Nose for Microbiological Quality Control of Food Products

    OpenAIRE

    Falasconi, M.; I. Concina; E. Gobbi; Sberveglieri, V.; A. Pulvirenti; G. Sberveglieri

    2012-01-01

    Electronic noses (ENs) have recently emerged as valuable candidates in various areas of food quality control and traceability, including microbial contamination diagnosis. In this paper, the EN technology for microbiological screening of food products is reviewed. Four paradigmatic and diverse case studies are presented: (a) Alicyclobacillus spp. spoilage of fruit juices, (b) early detection of microbial contamination in processed tomatoes, (c) screening of fungal and fumonisin contamination ...

  9. Learner corpora: the case of the NOSE corpus

    Directory of Open Access Journals (Sweden)

    Ana Díaz-Negrillo

    2012-02-01

    Full Text Available This paper provides a brief overview of the scope of learner corpus research and describes a learner corpus by Spanish university students of English, the NOn-native Spanish corpus of English (NOSE. It presents the corpus data, its annotation and how it can be retrieved and exploited for research purposes in the areas of interlanguage studies and automatic recognition of learner-specific features. It also reviews the various research topics that have been investigated in the corpus.

  10. A numerical model for bird strike on sidewall structure of an aircraft nose

    Directory of Open Access Journals (Sweden)

    Liu Jun

    2014-06-01

    Full Text Available In order to examine the potential of using the coupled smooth particles hydrodynamic (SPH and finite element (FE method to predict the dynamic responses of aircraft structures in bird strike events, bird-strike tests on the sidewall structure of an aircraft nose are carried out and numerically simulated. The bird is modeled with SPH and described by the Murnaghan equation of state, while the structure is modeled with finite elements. A coupled SPH–FE method is developed to simulate the bird-strike tests and a numerical model is established using a commercial software PAM-CRASH. The bird model shows no signs of instability and correctly modeled the break-up of the bird into particles. Finally the dynamic response such as strains in the skin is simulated and compared with test results, and the simulated deformation and fracture process of the sidewall structure is compared with images recorded by a high speed camera. Good agreement between the simulation results and test data indicates that the coupled SPH–FE method can provide a very powerful tool in predicting the dynamic responses of aircraft structures in events of bird strike.

  11. Effect of roughness of the blunted cone nose-tip on laminar-turbulent transition

    Science.gov (United States)

    Bountin, D. A.; Gromyko, Yu. V.; Polivanov, P. A.; Sidorenko, A. A.; Maslov, A. A.

    2016-10-01

    Hypersonic boundary layer stability and transition were studied experimentally and numerically for the test case of 7° cone model with blunt nose-tip. The experiments were performed for M=6, heat flux distributions and wall pressure pulsations were measured. It was obtained that the angle of cover and size of bluntness significantly affects on the transition location. Real hypersonic vehicle is equipped by thermal protection systems (TPS) which have a surface roughness (joints and connecting elements). Furthermore the surface of the elements of TPS is not smooth and has some relatively uniform roughness, which can vary during flight. Roughness size can change during thermal ablation or destruction, in addition elements of isolated roughness comparable with a thickness of the boundary layer may appear on surface (caverns, ledges, etc.,). These elements are additional receptivity areas where the additional perturbations are generated and developing in boundary layer that may cause premature laminar-turbulent transition. This effect has been studied for more than 50 years [17-3], but almost all the work devoted to the search of engineering correlations, but not to receptivity or stability problems. This effect needs to be studied more precisely.

  12. A numerical model for bird strike on sidewall structure of an aircraft nose

    Institute of Scientific and Technical Information of China (English)

    Liu Jun; Li Yulong; Gao Xiaosheng; Yu Xiancheng

    2014-01-01

    In order to examine the potential of using the coupled smooth particles hydrodynamic (SPH) and finite element (FE) method to predict the dynamic responses of aircraft structures in bird strike events, bird-strike tests on the sidewall structure of an aircraft nose are carried out and numerically simulated. The bird is modeled with SPH and described by the Murnaghan equation of state, while the structure is modeled with finite elements. A coupled SPH-FE method is developed to simulate the bird-strike tests and a numerical model is established using a commercial software PAM-CRASH. The bird model shows no signs of instability and correctly modeled the break-up of the bird into particles. Finally the dynamic response such as strains in the skin is simulated and compared with test results, and the simulated deformation and fracture process of the sidewall structure is compared with images recorded by a high speed camera. Good agreement between the simulation results and test data indicates that the coupled SPH-FE method can provide a very powerful tool in predicting the dynamic responses of aircraft structures in events of bird strike.

  13. Similar Fracture Patterns in Human Nose and Gothic Cathedral.

    Science.gov (United States)

    Lee, Shu Jin; Tse, Kwong Ming; Lee, Heow Pueh

    2015-10-01

    This study proposes that the bony anatomy of the human nose and masonry structure of the Gothic cathedral are geometrically similar, and have common fracture patterns. We also aim to correlate the fracture patterns observed in patients' midface structures with those seen in the Gothic cathedral using computational approach. CT scans of 33 patients with facial fractures were examined and compared with computer simulations of both the Gothic cathedral and human nose. Three similar patterns were found: (1) Cracks of the nasal arch with crumpling of the vertical buttresses akin to the damage seen during minor earthquakes; (2) lateral deviation of the central nasal arch and collapse of the vertical buttresses akin to those due to lateral forces from wind and in major earthquakes; and (3) Central arch collapse seen as a result of collapse under excessive dead weight. Interestingly, the finding of occult nasal and septal fractures in the mandible fractures with absence of direct nasal trauma highlights the possibility of transmission of forces from the foundation to the arch leading to structural failure. It was also found that the structural buttresses of the Gothic cathedral delineate the vertical buttresses in the human midface structure. These morphologic similarities between the human nose and Gothic cathedral will serve as a basis to study the biomechanics of nasal fractures. Identification of structural buttresses in a skeletal structure has important implications for reconstruction as reestablishment of structural continuity restores normal anatomy and architectural stability of the human midface structure.

  14. Classification of buildings mold threat using electronic nose

    Science.gov (United States)

    Łagód, Grzegorz; Suchorab, Zbigniew; Guz, Łukasz; Sobczuk, Henryk

    2017-07-01

    Mold is considered to be one of the most important features of Sick Building Syndrome and is an important problem in current building industry. In many cases it is caused by the rising moisture of building envelopes surface and exaggerated humidity of indoor air. Concerning historical buildings it is mostly caused by outdated raising techniques among that is absence of horizontal isolation against moisture and hygroscopic materials applied for construction. Recent buildings also suffer problem of mold risk which is caused in many cases by hermetization leading to improper performance of gravitational ventilation systems that make suitable conditions for mold development. Basing on our research there is proposed a method of buildings mold threat classification using electronic nose, based on a gas sensors array which consists of MOS sensors (metal oxide semiconductor). Used device is frequently applied for air quality assessment in environmental engineering branches. Presented results show the interpretation of e-nose readouts of indoor air sampled in rooms threatened with mold development in comparison with clean reference rooms and synthetic air. Obtained multivariate data were processed, visualized and classified using a PCA (Principal Component Analysis) and ANN (Artificial Neural Network) methods. Described investigation confirmed that electronic nose - gas sensors array supported with data processing enables to classify air samples taken from different rooms affected with mold.

  15. Review of the cetacean nose: form, function, and evolution.

    Science.gov (United States)

    Berta, Annalisa; Ekdale, Eric G; Cranford, Ted W

    2014-11-01

    The cetacean nose presents a unique suite of anatomical modifications. Key among these is posterior movement of the external nares from the tip of the rostrum to the top of the head. Concomitant with these anatomical changes are functional changes including the evolution of echolocation in odontocetes, and reduction of olfaction in Neoceti (crown odontocetes and mysticetes). Anatomical and embryological development of the nose in crown cetaceans is reviewed as well as their functional implications. A sequence of evolutionary transformations of the nose is proposed in the transition from a terrestrial to an aquatic lifestyle made by whales. Basilosaurids and all later whales reduce the nasal turbinates. The next stage characterizes Neoceti which exhibit reduction of the major olfactory structures, i.e. the ethmoturbinates, cribriform plate and maxilloturbinates with further reduction and subsequent loss in odontocetes. These anatomical modifications reflect underlying genetic changes such as the reduction of olfactory receptor genes, although mysticetes retain some olfactory abilities. Modifications of the facial and nasal region of odontocetes reflect specialization for biosonar sound production.

  16. Revisiting human nose anatomy: phylogenic and ontogenic perspectives.

    Science.gov (United States)

    Jankowski, Roger

    2011-11-01

    This review suggests revisiting nose anatomy by considering the ethmoidal labyrinths as part of the olfactory nose and not as paranasal sinuses. Phylogenetically, the olfactory and respiratory organs of the most primitive vertebrates are separated. Exaptation, a mechanism of evolution, may explain the fusion of the olfactory and respiratory organs in dipnoi. The respiratory and olfactory noses remain anatomically separated by the transverse lamina in most mammals, whose olfactory labyrinth is a blind recess housing the ethmoturbinates. In humans, the partitioning between the olfactory cleft and the ethmoid labyrinth seems to be a consequence of ethmoid bone remodeling induced by the acquisition of an upright posture. The ethmoid bone is derived from the cartilaginous nasal capsule of primitive vertebrates and considered to be a highly conserved region among the bony elements of the skull base. It appears to be involved only in housing and protecting the olfactory function. During the early stages of human fetal development, rupture of the oronasal membrane leads to the integration of the primary olfactory sac in the future respiratory organ. The cartilaginous nasal capsule appears in the tissue under the brain and around the olfactory channels. Its early fetal development is classically regarded as the beginning of paranasal sinus formation. From phylogenic and ontogenic perspectives, it may be regarded as the development of the olfactory labyrinth as modified by the remodeling process of the human face and skull base. The endochondral bony origin of the ethmoid labyrinths makes them substantially different from the other paranasal sinuses.

  17. SLN approach for nose-to-brain delivery of alprazolam.

    Science.gov (United States)

    Singh, Alok Pratap; Saraf, Shailendra K; Saraf, Shubhini A

    2012-12-01

    In the present study, alprazolam-loaded solid lipid nanoparticles were prepared and characterized. They were evaluated for their efficiency in nose-to-brain targeting and biodistribution in a suitable animal model after intranasal delivery. Solid lipid nanoparticles may offer an improvement to nose-to-brain drug delivery since they are able to protect the encapsulated drug from biological and/or chemical degradation. The distribution of the drug to different organs was recorded through biodistribution studies in male Wistar rats and gamma scintigraphy imaging in New Zealand rabbits by tagging the formulation with radioactive substance (99m)Tc. The radioactivity count of various organs was taken as a function of the drug concentration. The study reveals that alprazolam can be rapidly transferred to the brain via intranasal route, bypassing the blood-brain barrier and a direct nose-to-brain transfer. The enhanced rate and extent of transport may help in reducing the dose and dosing frequency, thereby providing ease for ambulatory patients.

  18. Detection And Identification Of Inflammatory Bowel Disease Electronic Nose

    Science.gov (United States)

    Covington, J. A.; Ouaret, N.; Gardner, J. W.; Nwokolo, C.; Bardhan, K. D.; Arasaradnam, R. P.

    2011-11-01

    Inflammatory bowel disease (IBD) is an inflammation of the lining of the human bowel and a major health issue in Europe. IBD carries with it significant morbidity from toxic treatment, surgery and a risk of developing bowel cancer. Thus there is a need for early identification of the disease using non-invasive tests. Present diagnostic techniques are based around invasive tests (i.e. endoscopy) and laboratory culture; the latter is limited as only 50% of the gut bacteria can be identified. Here we explore the use of an e-nose as a tool to detect and identify two IBDs (i.e. Crohn's disease (CD) & Ulcerative Colitis (UC)) based on headspace analysis from urine samples. We believe that the gut bacterial flora is altered by disease (due to fermentation) that in-turn modulates the gas composition within urine samples. 24 samples (9 CD, 6 UC, 9 controls) were analysed with an in-house e-nose and an Owlstone IMS instrument. Data analysis was performed using linear discriminant analysis (LDA and principal components analysis (PCA). Using the e-nose, LDA separates both disease groups and control, whilst PCA shows a small overlap of classes. The IMS data are more complex but shows some disease/control separation. We are presently collecting further samples for a larger study using more advanced data processing methods.

  19. Effect of trap color and height on captures of blunt-nosed and sharp-nosed leafhoppers (hemiptera: cicadellidae) and non-target arthropods in cranberry bogs

    Science.gov (United States)

    A series of field experiments were conducted in cranberry bogs in 2006-2010 to determine adult attraction of the two most economically important leafhopper pests of cultivated Vaccinium spp. in the northeast USA, the blunt-nosed leafhopper, Limotettix vaccinii, and sharp-nosed leafhopper, Scaphytopi...

  20. Dynamic smoothing of nanocomposite films

    NARCIS (Netherlands)

    Pei, Y.T.; Turkin, A; Chen, C.Q.; Shaha, K.P.; Vainshtein, D.; Hosson, J.Th.M. De

    2010-01-01

    In contrast to the commonly observed dynamic roughening in film growth we have observed dynamic smoothing in the growth of diamondlike-carbon nanocomposite (TiC/a-C) films up to 1.5 mu m thickness. Analytical and numerical simulations, based on the Edwards-Wilkinson model and the Mullins model, visu

  1. Nonlinear smoothing for random fields

    NARCIS (Netherlands)

    Aihara, Shin Ichi; Bagchi, Arunabha

    1995-01-01

    Stochastic nonlinear elliptic partial differential equations with white noise disturbances are studied in the countably additive measure set up. Introducing the Onsager-Machlup function to the system model, the smoothing problem for maximizing the modified likelihood functional is solved and the exp

  2. Arima model and exponential smoothing method: A comparison

    Science.gov (United States)

    Wan Ahmad, Wan Kamarul Ariffin; Ahmad, Sabri

    2013-04-01

    This study shows the comparison between Autoregressive Moving Average (ARIMA) model and Exponential Smoothing Method in making a prediction. The comparison is focused on the ability of both methods in making the forecasts with the different number of data sources and the different length of forecasting period. For this purpose, the data from The Price of Crude Palm Oil (RM/tonne), Exchange Rates of Ringgit Malaysia (RM) in comparison to Great Britain Pound (GBP) and also The Price of SMR 20 Rubber Type (cents/kg) with three different time series are used in the comparison process. Then, forecasting accuracy of each model is measured by examinethe prediction error that producedby using Mean Squared Error (MSE), Mean Absolute Percentage Error (MAPE), and Mean Absolute deviation (MAD). The study shows that the ARIMA model can produce a better prediction for the long-term forecasting with limited data sources, butcannot produce a better prediction for time series with a narrow range of one point to another as in the time series for Exchange Rates. On the contrary, Exponential Smoothing Method can produce a better forecasting for Exchange Rates that has a narrow range of one point to another for its time series, while itcannot produce a better prediction for a longer forecasting period.

  3. Microlayer during boiling in narrow slot channels

    Science.gov (United States)

    Diev, Mikhail D.; Leontiev, Alexander I.

    1997-01-01

    An international space station Alpha will have a two-phase thermal control system. Boiling of a liquid ammonia will be a process of heat collection in evaporative heat exchangers. Unfortunately, only little data is available for boiling heat transfer in microgravity. Geometries of boiling channels working good in normal gravity are not appropriate in microgravity, and special means should be worked out to avoid some undesired events. From this point of view, the narrow slot channels may be assumed as a promising geometry for microgravity operation. During boiling in narrow slots, the vapor bubbles are flattened between the channel walls. The vapor phase and the channel wall are separated by a thin liquid film which is known as a microlayer. The paper presents the experimental results compared to the theoretical analysis, the paper also shows the narrow slot channels as a perspective configuration for microgravity applications.

  4. Very Smooth Points of Spaces of Operators

    Indian Academy of Sciences (India)

    T S S R K Rao

    2003-02-01

    In this paper we study very smooth points of Banach spaces with special emphasis on spaces of operators. We show that when the space of compact operators is an -ideal in the space of bounded operators, a very smooth operator attains its norm at a unique vector (up to a constant multiple) and ( ) is a very smooth point of the range space. We show that if for every equivalent norm on a Banach space, the dual unit ball has a very smooth point then the space has the Radon–Nikodým property. We give an example of a smooth Banach space without any very smooth points.

  5. Efficient, Narrow-Pass-Band Optical Filters

    Science.gov (United States)

    Sandford, Stephen P.

    1996-01-01

    Optical filters with both narrow pass bands and high efficiencies fabricated to design specifications. Offer tremendous improvements in performance for number of optical (including infrared) systems. In fiber-optic and free-space communication systems, precise frequency discrimination afforded by narrow pass bands of filters provide higher channel capacities. In active and passive remote sensors like lidar and gas-filter-correlation radiometers, increased efficiencies afforded by filters enhance detection of small signals against large background noise. In addition, sizes, weights, and power requirements of many optical and infrared systems reduced by taking advantage of gains in signal-to-noise ratios delivered by filters.

  6. On Narrow Nucleon Excitation N*(1685)

    CERN Document Server

    Kuznetsov, V; Thuermann, M

    2011-01-01

    We collected notes and simple estimates about putative narrow nucleon N*(1685) - the candidate for the non-strange member of the exotic anti-decuplet of baryons. In particular, we consider the recent high precision data on eta photoproduction off free proton obtained by the Crystal Ball Collaboration at MAMI. We show that it is difficult to describe peculiarities of these new data in the invariant energy interval of W ~ 1650-1750 MeV in terms of known wide resonances. Using very simple estimates, we show that the data may indicate an existence of a narrow N*(1685) with small photocoupling to the proton.

  7. Application of electronic nose and electronic tongue in the dairy industry

    OpenAIRE

    Milna Tudor Kalit; Ksenija Marković; Samir Kalit; Nada Vahčić; Jasmina Havranek

    2014-01-01

    Electronic nose (e-nose) and electronic tongue (e-tongue) instrumental systems were designed to crudely mimic human olfactory and taste sensory organs and are composed of an array of sensors. Complex data sets from electronic nose and electronic tongue signals combined with multivariate statistics represent rapid and efficient tools for classification, discrimination, recognition and identification of samples, as well as for the prediction of concentrations of different compounds. A wide vari...

  8. An electronic nose for the detection of Sarin, Soman and Tabun mimics and interfering agents

    OpenAIRE

    2014-01-01

    An electronic nose system (E-nose) with metal oxide semiconductor sensors (MOS) has been designed to discriminate and quantify different chemical warfare agents (CWA) mimics. The E-nose consists of an array of commercial MOS for different gases, two sensors for temperature sensing, a sample handling system, a data acquisition system and a laptop with the data acquisition system control. With this device, discrimination studies have been carried out to detect specific CWA simulants...

  9. Graphene-Based Chemical Vapor Sensors for Electronic Nose Applications

    Science.gov (United States)

    Nallon, Eric C.

    An electronic nose (e-nose) is a biologically inspired device designed to mimic the operation of the olfactory system. The e-nose utilizes a chemical sensor array consisting of broadly responsive vapor sensors, whose combined response produces a unique pattern for a given compound or mixture. The sensor array is inspired by the biological function of the receptor neurons found in the human olfactory system, which are inherently cross-reactive and respond to many different compounds. The use of an e-nose is an attractive approach to predict unknown odors and is used in many fields for quantitative and qualitative analysis. If properly designed, an e-nose has the potential to adapt to new odors it was not originally designed for through laboratory training and algorithm updates. This would eliminate the lengthy and costly R&D costs associated with materiel and product development. Although e-nose technology has been around for over two decades, much research is still being undertaken in order to find new and more diverse types of sensors. Graphene is a single-layer, 2D material comprised of carbon atoms arranged in a hexagonal lattice, with extraordinary electrical, mechanical, thermal and optical properties due to its 2D, sp2-bonded structure. Graphene has much potential as a chemical sensing material due to its 2D structure, which provides a surface entirely exposed to its surrounding environment. In this configuration, every carbon atom in graphene is a surface atom, providing the greatest possible surface area per unit volume, so that electron transport is highly sensitive to adsorbed molecular species. Graphene has gained much attention since its discovery in 2004, but has not been realized in many commercial electronics. It has the potential to be a revolutionary material for use in chemical sensors due to its excellent conductivity, large surface area, low noise, and versatile surface for functionalization. In this work, graphene is incorporated into a

  10. Prospective Study of the Surgical Techniques Used in Primary Rhinoplasty on the Caucasian Nose and Comparison of the Preoperative and Postoperative Anthropometric Nose Measurements

    Directory of Open Access Journals (Sweden)

    Berger, Cezar Augusto Sarraf

    2014-12-01

    Full Text Available Introduction The knowledge and study of surgical techniques and anthropometric measurements of the nose make possible a qualitative and quantitative analysis of surgical results. Objective Study the main technique used in rhinoplasty on Caucasian noses and compare preoperative and postoperative anthropometric measurements of the nose. Methods A prospective study with 170 patients was performed at a private hospital. Data were collected using the Electronic System Integrated of Protocols software (Sistema Integrado de Protocolos Eletrônicos, SINPE©. The surgical techniques used in the nasal dorsum and tip were evaluated. Preoperative and 12-month follow-up photos as well as the measurements compared with the ideal aesthetic standard of a Caucasian nose were analyzed objectively. Student t test and standard deviation test were applied. Results There was a predominance of endonasal access (94.4%. The most common dorsum technique was hump removal (33.33%, and the predominance of sutures (24.76% was observed on the nasal tip, with the lateral intercrural the most frequent (32.39%. Comparison between preoperative and postoperative photos found statistically significant alterations on the anthropometric measurements of the noses. Conclusion The main surgical techniques on Caucasian noses were evaluated, and a great variety was found. The evaluation of anthropometric measurements of the nose proved the efficiency of the performed procedures.

  11. Prospective Study of the Surgical Techniques Used in Primary Rhinoplasty on the Caucasian Nose and Comparison of the Preoperative and Postoperative Anthropometric Nose Measurements

    Science.gov (United States)

    Berger, Cezar Augusto Sarraf; Freitas, Renato da Silva; Malafaia, Osvaldo; Pinto, José Simão de Paula; Macedo Filho, Evaldo Dacheux; Mocellin, Marcos; Fagundes, Marina Serrato Coelho

    2014-01-01

    Introduction The knowledge and study of surgical techniques and anthropometric measurements of the nose make possible a qualitative and quantitative analysis of surgical results. Objective Study the main technique used in rhinoplasty on Caucasian noses and compare preoperative and postoperative anthropometric measurements of the nose. Methods A prospective study with 170 patients was performed at a private hospital. Data were collected using the Electronic System Integrated of Protocols software (Sistema Integrado de Protocolos Eletrônicos, SINPE©). The surgical techniques used in the nasal dorsum and tip were evaluated. Preoperative and 12-month follow-up photos as well as the measurements compared with the ideal aesthetic standard of a Caucasian nose were analyzed objectively. Student t test and standard deviation test were applied. Results There was a predominance of endonasal access (94.4%). The most common dorsum technique was hump removal (33.33%), and the predominance of sutures (24.76%) was observed on the nasal tip, with the lateral intercrural the most frequent (32.39%). Comparison between preoperative and postoperative photos found statistically significant alterations on the anthropometric measurements of the noses. Conclusion The main surgical techniques on Caucasian noses were evaluated, and a great variety was found. The evaluation of anthropometric measurements of the nose proved the efficiency of the performed procedures. PMID:25992149

  12. Metal Oxide Sensors for Electronic Noses and Their Application to Food Analysis

    Science.gov (United States)

    Berna, Amalia

    2010-01-01

    Electronic noses (E-noses) use various types of electronic gas sensors that have partial specificity. This review focuses on commercial and experimental E-noses that use metal oxide semi-conductors. The review covers quality control applications to food and beverages, including determination of freshness and identification of contaminants or adulteration. Applications of E-noses to a wide range of foods and beverages are considered, including: meat, fish, grains, alcoholic drinks, non-alcoholic drinks, fruits, milk and dairy products, olive oils, nuts, fresh vegetables and eggs. PMID:22319332

  13. Metal Oxide Sensors for Electronic Noses and Their Application to Food Analysis

    Directory of Open Access Journals (Sweden)

    Amalia Berna

    2010-04-01

    Full Text Available Electronic noses (E-noses use various types of electronic gas sensors that have partial specificity. This review focuses on commercial and experimental E-noses that use metal oxide semi-conductors. The review covers quality control applications to food and beverages, including determination of freshness and identification of contaminants or adulteration. Applications of E-noses to a wide range of foods and beverages are considered, including: meat, fish, grains, alcoholic drinks, non-alcoholic drinks, fruits, milk and dairy products, olive oils, nuts, fresh vegetables and eggs.

  14. A Novel Semi-Supervised Electronic Nose Learning Technique: M-Training

    Directory of Open Access Journals (Sweden)

    Pengfei Jia

    2016-03-01

    Full Text Available When an electronic nose (E-nose is used to distinguish different kinds of gases, the label information of the target gas could be lost due to some fault of the operators or some other reason, although this is not expected. Another fact is that the cost of getting the labeled samples is usually higher than for unlabeled ones. In most cases, the classification accuracy of an E-nose trained using labeled samples is higher than that of the E-nose trained by unlabeled ones, so gases without label information should not be used to train an E-nose, however, this wastes resources and can even delay the progress of research. In this work a novel multi-class semi-supervised learning technique called M-training is proposed to train E-noses with both labeled and unlabeled samples. We employ M-training to train the E-nose which is used to distinguish three indoor pollutant gases (benzene, toluene and formaldehyde. Data processing results prove that the classification accuracy of E-nose trained by semi-supervised techniques (tri-training and M-training is higher than that of an E-nose trained only with labeled samples, and the performance of M-training is better than that of tri-training because more base classifiers can be employed by M-training.

  15. Maximal right smooth extension chains

    CERN Document Server

    Huang, Yun Bao

    2010-01-01

    If $w=u\\alpha$ for $\\alpha\\in \\Sigma=\\{1,2\\}$ and $u\\in \\Sigma^*$, then $w$ is said to be a \\textit{simple right extension}of $u$ and denoted by $u\\prec w$. Let $k$ be a positive integer and $P^k(\\epsilon)$ denote the set of all $C^\\infty$-words of height $k$. Set $u_{1},\\,u_{2},..., u_{m}\\in P^{k}(\\epsilon)$, if $u_{1}\\prec u_{2}\\prec ...\\prec u_{m}$ and there is no element $v$ of $P^{k}(\\epsilon)$ such that $v\\prec u_{1}\\text{or} u_{m}\\prec v$, then $u_{1}\\prec u_{2}\\prec...\\prec u_{m}$ is said to be a \\textit{maximal right smooth extension (MRSE) chains}of height $k$. In this paper, we show that \\textit{MRSE} chains of height $k$ constitutes a partition of smooth words of height $k$ and give the formula of the number of \\textit{MRSE} chains of height $k$ for each positive integer $k$. Moreover, since there exist the minimal height $h_1$ and maximal height $h_2$ of smooth words of length $n$ for each positive integer $n$, we find that \\textit{MRSE} chains of heights $h_1-1$ and $h_2+1$ are good candidates t...

  16. Electronic Nose Functionality for Breath Gas Analysis during Parabolic Flight

    Science.gov (United States)

    Dolch, Michael E.; Hummel, Thomas; Fetter, Viktor; Helwig, Andreas; Lenic, Joachim; Moukhamedieva, Lana; Tsarkow, Dimitrij; Chouker, Alexander; Schelling, Gustav

    2017-02-01

    The presence of humans in space represents a constant threat for their health and safety. Environmental factors such as living in a closed confinement, as well as exposure to microgravity and radiation, are associated with significant changes in bone metabolism, muscular atrophy, and altered immune response, which has impacts on human performance and possibly results in severe illness. Thus, maintaining and monitoring of crew health status has the highest priority to ensure whole mission success. With manned deep space missions to moon or mars appearing at the horizon where short-term repatriation back to earth is impossible the availability of appropriate diagnostic platforms for crew health status is urgently needed. In response to this need, the present experiment evaluated the functionality and practicability of a metal oxide based sensor system (eNose) together with a newly developed breath gas collecting device under the condition of altering acceleration. Parabolic flights were performed with an Airbus A300 ZeroG at Bordeaux, France. Ambient air and exhaled breath of five healthy volunteers was analyzed during steady state flight and parabolic flight maneuvres. All volunteers completed the study, the breath gas collecting device valves worked appropriately, and breathing through the collecting device was easy and did not induce discomfort. During breath gas measurements, significant changes in metal oxide sensors, mainly sensitive to aromatic and sulphur containing compounds, were observed with alternating conditions of acceleration. Similarly, metal oxide sensors showed significant changes in all sensors during ambient air measurements. The eNose as well as the newly developed breath gas collecting device, showed appropriate functionality and practicability during alternating conditions of acceleration which is a prerequisite for the intended use of the eNose aboard the International Space Station (ISS) for breath gas analysis and crew health status

  17. Electronic Nose Functionality for Breath Gas Analysis during Parabolic Flight

    Science.gov (United States)

    Dolch, Michael E.; Hummel, Thomas; Fetter, Viktor; Helwig, Andreas; Lenic, Joachim; Moukhamedieva, Lana; Tsarkow, Dimitrij; Chouker, Alexander; Schelling, Gustav

    2017-06-01

    The presence of humans in space represents a constant threat for their health and safety. Environmental factors such as living in a closed confinement, as well as exposure to microgravity and radiation, are associated with significant changes in bone metabolism, muscular atrophy, and altered immune response, which has impacts on human performance and possibly results in severe illness. Thus, maintaining and monitoring of crew health status has the highest priority to ensure whole mission success. With manned deep space missions to moon or mars appearing at the horizon where short-term repatriation back to earth is impossible the availability of appropriate diagnostic platforms for crew health status is urgently needed. In response to this need, the present experiment evaluated the functionality and practicability of a metal oxide based sensor system (eNose) together with a newly developed breath gas collecting device under the condition of altering acceleration. Parabolic flights were performed with an Airbus A300 ZeroG at Bordeaux, France. Ambient air and exhaled breath of five healthy volunteers was analyzed during steady state flight and parabolic flight maneuvres. All volunteers completed the study, the breath gas collecting device valves worked appropriately, and breathing through the collecting device was easy and did not induce discomfort. During breath gas measurements, significant changes in metal oxide sensors, mainly sensitive to aromatic and sulphur containing compounds, were observed with alternating conditions of acceleration. Similarly, metal oxide sensors showed significant changes in all sensors during ambient air measurements. The eNose as well as the newly developed breath gas collecting device, showed appropriate functionality and practicability during alternating conditions of acceleration which is a prerequisite for the intended use of the eNose aboard the International Space Station (ISS) for breath gas analysis and crew health status

  18. Narrow-Band Applications of Communications Satellites.

    Science.gov (United States)

    Cowlan, Bert; Horowitz, Andrew

    This paper attempts to describe the advantages of "narrow-band" applications of communications satellites for education. It begins by discussing the general controversy surrounding the use of satellites in education, by placing the concern within the larger context of the general debate over the uses of new technologies in education, and by…

  19. Narrow vision after view-broadening travel.

    Science.gov (United States)

    Melo, Mariana de Mendonça; Ciriano, Jose P Martinez; van Genderen, Perry J J

    2008-01-01

    Loss of vision is a threatening presentation of disease. We describe a case of acute idiopathic blind spot enlargement in a 26-year-old male traveler who presented with narrow vision after a journey to Indonesia. Although the patient used mefloquine at time of presentation, we were unable to retrieve sound data incriminating mefloquine in this rare eye disorder.

  20. Anaphylactic reaction following administration of nose drops containing benzalkonium chloride

    Directory of Open Access Journals (Sweden)

    Mezger Elke

    2012-10-01

    Full Text Available Abstract We describe a case of anaphylactic reaction in a 46-year-old female post application of decongestant nose drops containing benzalkonium chloride (BAC. With some latency, the patient complained of cough, dyspnea, sensation of heat, croakiness and pruritus. Since she showed all of these symptoms, typical of an anaphylactic reaction, we proceeded some weeks later with a prick test with solutions containing BAC, a cationic surfactant commonly used as an antibacterial preservative in many medical solutions. The prick test was positive, confirming the assumption of a hypersensitive reaction to BAC.

  1. Anaphylactic reaction following administration of nose drops containing benzalkonium chloride

    Science.gov (United States)

    2012-01-01

    We describe a case of anaphylactic reaction in a 46-year-old female post application of decongestant nose drops containing benzalkonium chloride (BAC). With some latency, the patient complained of cough, dyspnea, sensation of heat, croakiness and pruritus. Since she showed all of these symptoms, typical of an anaphylactic reaction, we proceeded some weeks later with a prick test with solutions containing BAC, a cationic surfactant commonly used as an antibacterial preservative in many medical solutions. The prick test was positive, confirming the assumption of a hypersensitive reaction to BAC. PMID:23078861

  2. Nose-To-Brain Delivery of PLGA-Diazepam Nanoparticles.

    Science.gov (United States)

    Sharma, Deepak; Sharma, Rakesh Kumar; Sharma, Navneet; Gabrani, Reema; Sharma, Sanjeev K; Ali, Javed; Dang, Shweta

    2015-10-01

    The objective of the present investigation was to optimize diazepam (Dzp)-loaded poly(lactic-co-glycolic acid) nanoparticles (NP) to achieve delivery in the brain through intranasal administration. Dzp nanoparticles (DNP) were formulated by nanoprecipitation and optimized using Box-Behnken design. The influence of various independent process variables (polymer, surfactant, aqueous to organic (w/o) phase ratio, and drug) on resulting properties of DNP (z-average and drug entrapment) was investigated. Developed DNP showed z-average 148-337 d.nm, polydispersity index 0.04-0.45, drug entrapment 69-92%, and zeta potential in the range of -15 to -29.24 mV. Optimized DNP were further analyzed by differential scanning calorimetry (DSC), Fourier transform infrared spectroscopy (FTIR), ex-vivo drug release, and in-vitro cytotoxicity. Ex-vivo drug release study via sheep nasal mucosa from DNP showed a controlled release of 64.4% for 24 h. 3-[4,5-Dimethylthiazol-2-yl]-2,5-diphenyltetrazolium bromide (MTT) assay performed on Vero cell line showed less toxicity for DNP as compared to Dzp suspension (DS). Gamma scintigraphy and biodistribution study of DNP and DS was performed on Sprague-Dawley rats using technetium-99m-labeled ((99m)Tc) Dzp formulations to investigate the nose-to-brain drug delivery pathway. Brain/blood uptake ratios, drug targeting efficiency, and direct nose-to-brain transport were found to be 1.23-1.45, 258, and 61% for (99m)Tc-DNP (i.n) compared to (99m)Tc-DS (i.n) (0.38-1.06, 125, and 1%). Scintigraphy images showed uptake of Dzp from nose-to-brain, and this observation was in agreement with the biodistribution results. These results suggest that the developed poly(D,L-lactide-co-glycolide) (PLGA) NP could serve as a potential carrier of Dzp for nose-to-brain delivery in outpatient management of status epilepticus.

  3. Absolute and contrast infrared signatures from missile noses

    Science.gov (United States)

    Tofani, Alessandro

    1990-10-01

    The infrared radiant intensity and radiative contrast produced by the aerodynamic and solar heating of missile noses have been obtained by computer simulating the corresponding temperature distributions and by taking into account the effects of both atmosphere (absorption and self-emission) and target geometry (distance, aspect and elevation angles). Six target classes have been considered, including cruise missiles, air-to-air and surface-to-surface missiles, and ballistic missiles. The comparison between radiative quantities in the 3 to 5 μm and S to 12 μm atmospheric transmittance windows gives the optimum spectral band for target detection in each point of its trajectory.

  4. Bat white-nose syndrome: An emerging fungal pathogen?

    Science.gov (United States)

    Blehert, D.S.; Hicks, A.C.; Behr, M.; Meteyer, C.U.; Berlowski-Zier, B. M.; Buckles, E.L.; Coleman, J.T.H.; Darling, S.R.; Gargas, A.; Niver, R.; Okoniewski, J.C.; Rudd, R.J.; Stone, W.B.

    2009-01-01

    White-nose syndrome (WNS) is a condition associated with an unprecedented bat mortality event in the northeastern United States. Since the winter of 2006*2007, bat declines exceeding 75% have been observed at surveyed hibernacula. Affected bats often present with visually striking white fungal growth on their muzzles, ears, and/or wing membranes. Direct microscopy and culture analyses demonstrated that the skin of WNS-affected bats is colonized by a psychro-philic fungus that is phylogenetically related to Geomyces spp. but with a conidial morphology distinct from characterized members of this genus. This report characterizes the cutaneous fungal infection associated with WNS.

  5. Bat white-nose syndrome: an emerging fungal pathogen?

    Science.gov (United States)

    Blehert, David S; Hicks, Alan C; Behr, Melissa; Meteyer, Carol U; Berlowski-Zier, Brenda M; Buckles, Elizabeth L; Coleman, Jeremy T H; Darling, Scott R; Gargas, Andrea; Niver, Robyn; Okoniewski, Joseph C; Rudd, Robert J; Stone, Ward B

    2009-01-09

    White-nose syndrome (WNS) is a condition associated with an unprecedented bat mortality event in the northeastern United States. Since the winter of 2006*2007, bat declines exceeding 75% have been observed at surveyed hibernacula. Affected bats often present with visually striking white fungal growth on their muzzles, ears, and/or wing membranes. Direct microscopy and culture analyses demonstrated that the skin of WNS-affected bats is colonized by a psychrophilic fungus that is phylogenetically related to Geomyces spp. but with a conidial morphology distinct from characterized members of this genus. This report characterizes the cutaneous fungal infection associated with WNS.

  6. Hızma Induced Papul of Nose Mimicking Pyogenic Granuloma

    Directory of Open Access Journals (Sweden)

    Mualla Polat

    2014-09-01

    Full Text Available The application of body piercing is popular among young people, who consider it as a sign of marginality, beauty, or group identity. Piercing procedure is observed to cause a large number of complications such as infections, pain, inflammatory reactions, bleeding, dental fractures or fissures, and gingival damage, etc., mostly in young individuals. Hizma is a traditional body ornament worn by Anatolian women via a piercing procedure. Herein, we describe a papule of nose mimicking pyogenic granuloma as an uncommon complication of Hızma.

  7. Pharmacology of airway smooth muscle proliferation

    NARCIS (Netherlands)

    Gosens, Reinoud; Roscioni, Sara S.; Dekkers, Bart G. J.; Pera, Tonio; Schmidt, Martina; Schaafsma, Dedmer; Zaagsma, Johan; Meurs, Herman

    2008-01-01

    Airway smooth muscle thickening is a pathological feature that contributes significantly to airflow limitation and airway hyperresponsiveness in asthma. Ongoing research efforts aimed at identifying the mechanisms responsible for the increased airway smooth muscle mass have indicated that hyperplasi

  8. Smooth Optimization Approach for Sparse Covariance Selection

    OpenAIRE

    Lu, Zhaosong

    2009-01-01

    In this paper we first study a smooth optimization approach for solving a class of nonsmooth strictly concave maximization problems whose objective functions admit smooth convex minimization reformulations. In particular, we apply Nesterov's smooth optimization technique [Y.E. Nesterov, Dokl. Akad. Nauk SSSR, 269 (1983), pp. 543--547; Y. E. Nesterov, Math. Programming, 103 (2005), pp. 127--152] to their dual counterparts that are smooth convex problems. It is shown that the resulting approach...

  9. A SAS IML Macro for Loglinear Smoothing

    Science.gov (United States)

    Moses, Tim; von Davier, Alina

    2011-01-01

    Polynomial loglinear models for one-, two-, and higher-way contingency tables have important applications to measurement and assessment. They are essentially regarded as a smoothing technique, which is commonly referred to as loglinear smoothing. A SAS IML (SAS Institute, 2002a) macro was created to implement loglinear smoothing according to…

  10. Modular design of long narrow scintillating cells for ILC detector

    Energy Technology Data Exchange (ETDEWEB)

    Beznosko, D.; Blazey, G.; Dyshkant, A.; Maloney, J.; Rykalin, V.; /Northern Illinois U.; Schellpfeffer, J.; /Fermilab

    2005-09-01

    The experimental results for the narrow scintillating elements with effective area about 20 cm{sup 2} are reported. The elements were formed from the single piece of scintillator and were read out via wavelength shifting fibers with the MRS (Metal/Resistor/Semiconductor) photodiodes on both ends of each fiber. The formation of the cells from the piece of scintillator by using grooves is discussed. The cell performance was tested using the radioactive source by measuring the PMT current and a single rate after amplifier and discrimination with threshold at about three photo electrons in each channel and quad coincidences (double coincidences between sensors on each fiber and double coincidences between two neighboring fibers). This result is of high importance for large multi-channel systems, i.e. module may be used as an active element for calorimeter or muon system for the design of the future electron-positron linear collider detector because cell effective area can be smoothly enlarged or reduced (to 4 cm{sup 2} definitely).

  11. Optogenetic Central Amygdala Stimulation Intensifies and Narrows Motivation for Cocaine.

    Science.gov (United States)

    Warlow, Shelley M; Robinson, Mike J F; Berridge, Kent C

    2017-08-30

    Addiction is often characterized by intense motivation for a drug, which may be narrowly focused at the expense of other rewards. Here, we examined the role of amygdala-related circuitry in the amplification and narrowing of motivation focus for intravenous cocaine. We paired optogenetic channelrhodopsin (ChR2) stimulation in either central nucleus of amygdala (CeA) or basolateral amygdala (BLA) of female rats with one particular nose-poke porthole option for earning cocaine infusions (0.3 mg/kg, i.v.). A second alternative porthole earned identical cocaine but without ChR2 stimulation. Consequently, CeA rats quickly came to pursue their CeA ChR2-paired cocaine option intensely and exclusively, elevating cocaine intake while ignoring their alternative cocaine alone option. By comparison, BLA ChR2 pairing failed to enhance cocaine motivation. CeA rats also emitted consummatory bites toward their laser-paired porthole, suggesting that higher incentive salience made that cue more attractive. A separate progressive ratio test of incentive motivation confirmed that CeA ChR2 amplified rats' motivation, raising their breakpoint effort price for cocaine by 10-fold. However, CeA ChR2 laser on its own lacked any reinforcement value: laser by itself was never self-stimulated, not even by the same rats in which it amplified motivation for cocaine. Conversely, CeA inhibition by muscimol/baclofen microinjections prevented acquisition of cocaine self-administration and laser preference, whereas CeA inhibition by optogenetic halorhodopsin suppressed cocaine intake, indicating that CeA circuitry is needed for ordinary cocaine motivation. We conclude that CeA ChR2 excitation paired with a cocaine option specifically focuses and amplifies motivation to produce intense pursuit and consumption focused on that single target.SIGNIFICANCE STATEMENT In addiction, intense incentive motivation often becomes narrowly focused on a particular drug of abuse. Here we show that pairing central

  12. Sonar beam dynamics in leaf-nosed bats.

    Science.gov (United States)

    Linnenschmidt, Meike; Wiegrebe, Lutz

    2016-07-07

    Ultrasonic emissions of bats are directional and delimit the echo-acoustic space. Directionality is quantified by the aperture of the sonar beam. Recent work has shown that bats often widen their sonar beam when approaching movable prey or sharpen their sonar beam when navigating through cluttered habitats. Here we report how nose-emitting bats, Phyllostomus discolor, adjust their sonar beam to object distance. First, we show that the height and width of the bats sonar beam, as imprinted on a parabolic 45 channel microphone array, varies even within each animal and this variation is unrelated to changes in call level or spectral content. Second, we show that these animals are able to systematically decrease height and width of their sonar beam while focusing on the approaching object. Thus it appears that sonar beam sharpening is a further, facultative means of reducing search volume, likely to be employed by stationary animals when the object position is close and unambiguous. As only half of our individuals sharpened their beam onto the approaching object we suggest that this strategy is facultative, under voluntary control, and that beam formation is likely mediated by muscular control of the acoustic aperture of the bats' nose leaf.

  13. When in doubt follow your nose – a wayfinding strategy

    Directory of Open Access Journals (Sweden)

    Tobias eMeilinger

    2014-11-01

    Full Text Available Route selection is governed by various strategies which often allow minimizing the required memory capacity. Previous research showed that navigators primarily remember information at route decision points and at route turns, rather than at intersections which required straight walking. However, when actually navigating the route or indicating directional decisions, navigators make fewer errors when they are required to walk straight. This tradeoff between location memory and route decisions accuracy was interpreted as a when in doubt follow your nose strategy which allows navigators to only memorize turns and walk straight by default, thus considerably reducing the number of intersections to memorize. These findings were based on newly learned routes. In the present study we show that such an asymmetry in route memory also prevails for planning routes within highly familiar environments. Participants planned route sequences between locations in their city of residency by pressing arrow keys on a keyboard. They tended to ignore straight walking intersections, but they ignored turns much less so. However, for reported intersections participants were quicker at indicating straight walking than turning. Together with results described in the literature, these findings suggest that a when in doubt follow your nose strategy is applied also within highly familiar spaces and might originate from limited working memory capacity during planning a route.

  14. [Lupus vulgaris manifestation as a destructive nose and facial tumor].

    Science.gov (United States)

    Haller, D; Reisser, C

    2009-04-01

    Lupus vulgaris is the most frequent manifestation of cutaneous tuberculosis, but in Europe it is limited to isolated cases. Mainly immunocompetent individuals are affected by this result of an endogenous reinfection on a lymphogenous-less frequently hematogenous-pathway. Lupus vulgaris has been observed to develop in more than 50% of all patients who already suffer from other manifestations of tuberculosis. The development of a squamous cell carcinoma in the lupus vulgaris is a rare complication; therefore, lupus vulgaris is deemed a facultative precancerosis.A 68-year-old female Serbo-Croatian patient presented with an extensive ulcerative nose and facial tumor. Her anamnesis included a squamous cell carcinoma of the nose that had been excised alio loco 3 years before. Further examinations revealed enlarged cervical lymphoma on both sides, and pulmonary metastases were also suspected. The tumor biopsy revealed a necrotic, granulomatous inflammation. No acid-fast rods were seen on Ziehl-Neelsen stain. The tuberculous origin of this ulcerative skin tumor-the lupus vulgaris-as an endogenous reinfection of pulmonary tuberculosis manifestation was confirmed by the detection of Mycobacterium tuberculosis DNA in polymerase chain reaction and the growth of Mycobacterium tuberculosis colonies in the bacterial culture (skin biopsy and bronchial secretion). The skin tumor as well as the pulmonary manifestation were successfully treated with combined tuberculostatic therapy and showed a dramatic response within 3 months.

  15. Electronic Noses for Composites Surface Contamination Detection in Aerospace Industry.

    Science.gov (United States)

    Vito, Saverio De; Miglietta, Maria Lucia; Massera, Ettore; Fattoruso, Grazia; Formisano, Fabrizio; Polichetti, Tiziana; Salvato, Maria; Alfano, Brigida; Esposito, Elena; Francia, Girolamo Di

    2017-04-02

    The full exploitation of Composite Fiber Reinforced Polymers (CFRP) in so-called green aircrafts design is still limited by the lack of adequate quality assurance procedures for checking the adhesive bonding assembly, especially in load-critical primary structures. In this respect, contamination of the CFRP panel surface is of significant concern since it may severely affect the bonding and the mechanical properties of the joint. During the last years, the authors have developed and tested an electronic nose as a non-destructive tool for pre-bonding surface inspection for contaminants detection, identification and quantification. Several sensors and sampling architectures have been screened in view of the high Technology Readiness Level (TRL) scenarios requirements. Ad-hoc pattern recognition systems have also been devised to ensure a fast and reliable assessment of the contamination status, by combining real time classifiers and the implementation of a suitable rejection option. Results show that e-noses could be used as first line low cost Non Destructive Test (NDT) tool in aerospace CFRP assembly and maintenance scenarios.

  16. Meat Quality Assessment by Electronic Nose (Machine Olfaction Technology

    Directory of Open Access Journals (Sweden)

    Sundar Balasubramanian

    2009-07-01

    Full Text Available Over the last twenty years, newly developed chemical sensor systems (so called “electronic noses” have made odor analyses possible. These systems involve various types of electronic chemical gas sensors with partial specificity, as well as suitable statistical methods enabling the recognition of complex odors. As commercial instruments have become available, a substantial increase in research into the application of electronic noses in the evaluation of volatile compounds in food, cosmetic and other items of everyday life is observed. At present, the commercial gas sensor technologies comprise metal oxide semiconductors, metal oxide semiconductor field effect transistors, organic conducting polymers, and piezoelectric crystal sensors. Further sensors based on fibreoptic, electrochemical and bi-metal principles are still in the developmental stage. Statistical analysis techniques range from simple graphical evaluation to multivariate analysis such as artificial neural network and radial basis function. The introduction of electronic noses into the area of food is envisaged for quality control, process monitoring, freshness evaluation, shelf-life investigation and authenticity assessment. Considerable work has already been carried out on meat, grains, coffee, mushrooms, cheese, sugar, fish, beer and other beverages, as well as on the odor quality evaluation of food packaging material. This paper describes the applications of these systems for meat quality assessment, where fast detection methods are essential for appropriate product management. The results suggest the possibility of using this new technology in meat handling.

  17. [Surgical reconstruction of large defects of the nose].

    Science.gov (United States)

    Hofer, S O P; Mureau, M A M

    2008-07-26

    --Skin cancer of the face is the most prevalent type of cancer. The large increase of the incidence of this type of cancer in recent years has resulted in an increase of skin cancer resections in the face. --Nasal defects are the most challenging of these facial defects. Nasal reconstruction requires reconstruction of three tissue layers: the inner mucosal lining, supporting structures (cartilage or bone) and the outer cutaneous lining. --The new inner lining should consist of well-vascularized thin tissue to prevent rejection of cartilage or bone in the supporting layer. For example, septal mucosa or skin can be used in various ways to reconstruct the inner lining. --The new supporting structures, consisting of transplanted cartilage or bone, should be strong enough to prevent contraction of the soft tissues--inner and outer lining--during wound healing. --The outer lining is reconstructed per subunit of the nose, e.g. nostril, ala nasi or ridge of the nose. Usually a paramedian forehead flap is used for the reconstruction of the outer lining.

  18. Signal processing inspired from the olfactory bulb for electronic noses

    Science.gov (United States)

    Jing, Ya-Qi; Meng, Qing-Hao; Qi, Pei-Feng; Zeng, Ming; Liu, Ying-Jie

    2017-01-01

    A bio-inspired signal processing method is proposed for electronic noses (e-noses). The proposed method contains an olfactory bulb model and a feature generation step. The structure of the olfactory bulb model is similar to the anatomical structure of mammals’ olfactory bulb. It consists of olfactory receptor neurons, mitral cells, granule cells, periglomerular cells, and short axon cells. This model uses gas sensors’ original response curves and transforms them to neuron spiking series no matter what kind the response curve is. This largely simplifies the follow-up feature generation step. Recurrence quantification analysis is employed to perform feature generation and the five most important features are selected. Finally, in order to verify the performance of the proposed method, seven kinds of Chinese liquors are tested and three classification methods are used to classify them. The experimental results demonstrate that the proposed method has a higher classification rate (99.05%) and also a steadier performance with the change of sensor number and types than the classic one.

  19. Estimation of bacteriological spoilage of pork cutlets by electronic nose.

    Science.gov (United States)

    Horváth, Kinga M; Seregély, Zs; Dalmadi, I; Andrássy, Eva; Farkas, J

    2007-06-01

    The utility of chemosensor array (EN) signals of head-space volatiles of aerobically stored pork cutlets as a non-invasive technique for monitoring their microbiological load was studied during storage at 4, 8 and 12 degrees C, respectively. The bacteriological quality of the meat samples was determined by standard total aerobic plate counts (TAPC) and colony count of selectively estimated Pseudomonas (PS) spp., the predominant aerobic spoilage bacteria. Statistical analysis of the electronic nose measurements were principal component analysis (PCA), and canonical discriminant analysis (CDA). Partial least squares (PLS) regression was used to model correlation between microbial loads and EN signal responses, the degree of bacteriological spoilage, independently of the temperature of the refrigerated storage. Sensor selection techniques were applied to reduce the dimensionality and more robust calibration models were computed by determining few individual sensors having the smallest cross correlations and highest correlations with the reference data. Correlations between the predicted and "real" values were given on cross-validated data from both data reduced models and for full calibrations using the 23 sensor elements. At the same time, sensorial quality of the raw cutlets was noted subjectively on faultiness of the odour and colour, and drip formation of the samples. These preliminary studies indicated that the electronic nose technique has a potential to detect bacteriological spoilage earlier or at the same time as olfactory quality deterioration.

  20. Smoothing of Piecewise Linear Paths

    Directory of Open Access Journals (Sweden)

    Michel Waringo

    2008-11-01

    Full Text Available We present an anytime-capable fast deterministic greedy algorithm for smoothing piecewise linear paths consisting of connected linear segments. With this method, path points with only a small influence on path geometry (i.e. aligned or nearly aligned points are successively removed. Due to the removal of less important path points, the computational and memory requirements of the paths are reduced and traversing the path is accelerated. Our algorithm can be used in many different applications, e.g. sweeping, path finding, programming-by-demonstration in a virtual environment, or 6D CNC milling. The algorithm handles points with positional and orientational coordinates of arbitrary dimension.

  1. Powerful narrow linewidth random fiber laser

    Science.gov (United States)

    Ye, Jun; Xu, Jiangming; Zhang, Hanwei; Zhou, Pu

    2017-03-01

    In this paper, we demonstrate a narrow linewidth random fiber laser, which employs a tunable pump laser to select the operating wavelength for efficiency optimization, a narrow-band fiber Bragg grating (FBG) and a section of single mode fiber to construct a half-open cavity, and a circulator to separate pump light input and random lasing output. Spectral linewidth down to 42.31 GHz is achieved through filtering by the FBG. When 8.97 W pump light centered at the optimized wavelength 1036.5 nm is launched into the half-open cavity, 1081.4 nm random lasing with the maximum output power of 2.15 W is achieved, which is more powerful than the previous reported results.

  2. Exciton absorption in narrow armchair graphene nanoribbons

    Science.gov (United States)

    Monozon, B. S.; Schmelcher, P.

    2016-11-01

    We develop an analytical approach to the exciton optical absorption for narrow gap armchair graphene nanoribbons (AGNR). We focus on the regime of dominant size quantization in combination with the attractive electron-hole interaction. An adiabatic separation of slow and fast motions leads via the two-body Dirac equation to the isolated and coupled subband approximations. Discrete and continuous exciton states are in general coupled and form quasi-Rydberg series of purely discrete and resonance type character. The corresponding oscillator strengths and widths are derived. We show that the exciton peaks are blue-shifted, become broader and increase in magnitude upon narrowing the ribbon. At the edge of a subband the singularity related to the 1D density of states is transformed into finite absorption via the presence of the exciton. Our analytical results are in good agreement with those obtained by other methods including numerical approaches. Estimates of the expected experimental values are provided for realistic AGNR.

  3. β2-Agonist induced cAMP is decreased in asthmatic airway smooth muscle due to increased PDE4D

    NARCIS (Netherlands)

    Trian, Thomas; Burgess, Janette K; Niimi, Kyoko; Moir, Lyn M; Ge, Qi; Berger, Patrick; Liggett, Stephen B; Black, Judith L; Oliver, Brian G

    2011-01-01

    BACKGROUND AND OBJECTIVE: Asthma is associated with airway narrowing in response to bronchoconstricting stimuli and increased airway smooth muscle (ASM) mass. In addition, some studies have suggested impaired β-agonist induced ASM relaxation in asthmatics, but the mechanism is not known. OBJECTIVE:

  4. 21 CFR 874.4420 - Ear, nose, and throat manual surgical instrument.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Ear, nose, and throat manual surgical instrument. 874.4420 Section 874.4420 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN..., and throat manual surgical instrument. (a) Identification. An ear, nose, and throat manual...

  5. Integration of electronic nose technology with spirometry: validation of a new approach for exhaled breath analysis

    NARCIS (Netherlands)

    de Vries, R.; Brinkman, P.; van der Schee, M.P.; Fens, N.; Dijkers, E.; Bootsma, S.K.; de Jongh, Franciscus H.C.; Sterk, P.J.

    2015-01-01

    New 'omics'-technologies have the potential to better define airway disease in terms of pathophysiological and clinical phenotyping. The integration of electronic nose (eNose) technology with existing diagnostic tests, such as routine spirometry, can bring this technology to 'point-of-care'. We

  6. Lupus vulgaris of external nose with septal perforation--a rarity in antibiotic era.

    Science.gov (United States)

    Garg, Ajay; Wadhera, Raman; Gulati, S P; Singh, Jagjit

    2010-07-01

    Lupus vulgaris (LV) is the commonest morphological variant of cutaneous tuberculosis. Case of LV of external nose extending to internal nose causing septal perforation is documented here. Histopathology of biopsy taken confirmed the diagnosis of LV. Patient responded well to Anti-tubercular therapy (ATT).

  7. A Combined CFD/Characteristic Method for Prediction and Design of Hypersonic Inlet with Nose Bluntness

    Science.gov (United States)

    Gao, Wenzhi; Li, Zhufei; Yang, Jiming

    Leading edge bluntness is widely used in hypersonic inlet design for thermal protection[1]. Detailed research of leading edge bluntness on hypersonic inlet has been concentrated on shock shape correlation[2], boundary layer flow[3], inlet performance[4], etc. It is well known that blunted noses cause detached bow shocks which generate subsonic regions around the noses and entropy layers in the flowfield.

  8. An analytical model for force prediction in ball nose micro milling of inclined surfaces

    DEFF Research Database (Denmark)

    Bissacco, Giuliano; Hansen, Hans Nørgaard; De Chiffre, Leonardo

    2010-01-01

    Ball nose micro milling is a key process for the generation of free form surfaces and inclined surfaces often present in mould inserts for micro replication. This paper presents a new cutting force model for ball nose micro milling that is capable of taking into account the effect of the edge rad...

  9. Analysis of New Aerodynamic Design of the Nose Cone Section Using CFD and SPH

    Directory of Open Access Journals (Sweden)

    Bogdan-Alexandru BELEGA

    2015-06-01

    Full Text Available A new nose cones concept that promises a gain in performance over existing conventional nose cones is discussed in this paper. It is shown that significant performance gains result from the adaptation of the exhaust flow to the ambient pressure. For this complex work, it was necessary to collect and study the various nose cone shapes and the equations describing them? The paper objective was to identify the types of nose cones with ejector channels and specific aerodynamic characteristics of different types of nose cones. The scope of this paper is to develop some prototype profiles with outstanding aerodynamic qualities and low cost for use in construction projects for missile increasing their range and effect on target. The motivation for such a work is caused by a lack of data on aerodynamics for profiles of some nose cones and especially improved aerodynamic qualities that can be used in designing missiles/ rockets. This design method consists of a geometry creation step in which a three-dimensional geometry is generated, a mathematical model presented and a simple flow analysis (FLUENT Simulation from SolidWorks2012 and ANSYS Simulation with SPH for fluid-structure interaction, step which predicts the air intake mass flow rate. Flow phenomena observed in numerical simulations during different nose cone operations are highlighted, critical design aspects and operation conditions are discussed, and performance characteristics of the selected nose cone are presented.

  10. 21 CFR 874.3620 - Ear, nose, and throat synthetic polymer material.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Ear, nose, and throat synthetic polymer material. 874.3620 Section 874.3620 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN..., and throat synthetic polymer material. (a) Identification. Ear, nose, and throat synthetic polymer...

  11. The pig's nose and its role in dominance relationships and harmful behaviour

    NARCIS (Netherlands)

    Camerlink, I.; Turner, S.P.

    2013-01-01

    Affiliative behaviour may have an essential role in many behavioural processes. Gently nosing between group members occurs in almost all social behavioural processes of pigs (Sus scrofa), but the reasons for its performance are unclear. We examined whether nosing between pigs was related to

  12. Narrow optical filtering with plasmonic nanoshells

    CERN Document Server

    Martynov, Y B; Tanachev, I A; Gladyshev, P P

    2011-01-01

    Narrow optical band pass filters are widely used in systems with optical processing of information, color displays development and optical computers. We show that such ultra filters can be created by means of nanoparticles which consist of a dielectric sphere and a metallic shell. The components can be adjusted such that there is a remarkable transparency at the desired wavelength range, while a strong absorption takes place outside of this region.

  13. Code optimizations for narrow bitwidth architectures

    OpenAIRE

    Bhagat, Indu

    2012-01-01

    This thesis takes a HW/SW collaborative approach to tackle the problem of computational inefficiency in a holistic manner. The hardware is redesigned by restraining the datapath to merely 16-bit datawidth (integer datapath only) to provide an extremely simple, low-cost, low-complexity execution core which is best at executing the most common case efficiently. This redesign, referred to as the Narrow Bitwidth Architecture, is unique in that although the datapath is squeezed to 16-bits...

  14. Income and Consumption Smoothing among US States

    DEFF Research Database (Denmark)

    Sørensen, Bent; Yosha, Oved

    states. The fraction of a shock to gross state products smoothed by the federal tax-transfer system is the same for various regions and other clubs of states. We calculate the scope for consumption smoothing within various regions and clubs, finding that most gains from risk sharing can be achieved......We quantify the amount of cross-sectional income and consumption smoothing achieved within subgroups of states, such as regions or clubs, e.g. the club of rich states. We find that there is much income smoothing between as well as within regions. By contrast, consumption smoothing occurs mainly...... within regions but not between regions. This suggests that capital markets transcend regional barriers while credit markets are regional in their nature. Smoothing within the club of rich states is accomplished mainly via capital markets whereas consumption smoothing is dominant within the club of poor...

  15. Band Gap Narrowing in Heavily Doped Silicon.

    Science.gov (United States)

    Gupta, Tapan Kumar

    Two analytic models for transport and band gap narrowing in heavily doped (N_{rm D} > 10^{20} cm^ {-3}) silicon have been set up and verified through measurements on n^{+} -p junction devices. The first model is based on calculation of the ratio of the charge present in the emitter of the n^{+} region of the junction to that of the charge present in the absence of band gap shrinkage. Fermi-Dirac statistics are employed and are found to have a significant effect at this doping level. The second model is based on current transport of minority carriers in the n^{+} region. In this model only two parameters need to be known, the diffusion coefficient and the diffusion length for minority carriers, to calculate the band gap narrowing. An empirical relation between band gap narrowing and donor concentration has also been established based on experimental values of diffusion coefficient and mobility. These models have been verified by several different experimental techniques including surface photovoltage, open circuit voltage decay, photoconductivity decay and modulation reflection spectroscopy. The results indicate that, in the impurity range above about 10^{20} cm^{-3}, Fermi-Dirac statistics must be invoked in order to achieve a satisfactory fit with experimental data.

  16. [Diseases of the nose and paranasal sinuses in workers of the woodworking industry].

    Science.gov (United States)

    Savov, A

    1988-01-01

    During preventive otorhinolaryngological examination of 262 workers from the plant for wood planes, subject to a combined effect of unfavourable microclimatic, dust, toxic (in particular formaldehyde) factors, are carried out profound studies of the nose and the cavities around the nose. More than 50% of the complains are of the nose-gullet which decrease with the increase of the length of service, while the objective changes in the mucous membrane of the nose raise high. In 70 (26.7%) of the workers are observed pathological changes, mainly of chronic hypertrophic rhinitis. Of special interest is the comparative high per cent of changed nasal architectonic (16.0%). In 43.5% of the cases with nasal diseases are established changes in the olfactory function (hyposmia I and II rate) of respiratory type. Deviation on behalf of the respiratory, motive and hemodynamic functions of the nose are observed.

  17. Electronic nose system combined with membrane interface probe for detection of VOCs in water

    Science.gov (United States)

    Cho, Junghwan; Howard, Zachary; Kurup, Pradeep

    2011-09-01

    This paper describes a novel electronic nose system combined with a membrane interface probe (MIP) for detecting volatile organic compounds (VOCs) in water. The MIP is an in situ tool that allows the detection of certain VOCs in the soil via a pushed or driven probe. The MIP was combined with a sensor array consisting of four different tin-oxide gas sensors known as an electronic nose (e-nose). The designed e-nose system was calibrated in aqueous media spiked with benzene, toluene, ethylbenzene, and p-xylene (BTEX) at concentrations of 100, 250, and 500 ppm. Since the experiment was conducted utilizing five repetitions for each analyte, a data set of 60 measurements was prepared for principal components analysis (PCA). The results of the PCA showed that two principal components contain more than 99% variance information and each VOC is separable and detectable by the e-nose.

  18. Comparison of Algorithms for an Electronic Nose in Identifying Liquors

    Institute of Scientific and Technical Information of China (English)

    Zhi-biao Shi; Tao Yu; Qun Zhao; Yang Li; Yu-bin Lan

    2008-01-01

    When the electronic nose is used to identify different varieties of distilled liquors, the pattern recognition algorithm is chosen on the basis of the experience, which lacks the guiding principle. In this research, the different brands of distilled spirits were identified using the pattern recognition algorithms (principal component analysis and the artificial neural network). The recognition rates of different algorithms were compared. The recognition rate of the Back Propagation Neural Network (BPNN) is the highest. Owing to the slow convergence speed of the BPNN, it tends easily to get into a local minimum. A chaotic BPNN was tried in order to overcome the disadvantage of the BPNN. The convergence speed of the chaotic BPNN is 75.5 times faster than that of the BPNN.

  19. An Artificial Nose Based on Microcantilever Array Sensors

    Energy Technology Data Exchange (ETDEWEB)

    Lang, H P [National Center of Competence in Research for Nanoscale Science, Institute of Physics of Univesity of Basel, Klingelbergstrasse 82, CH-4056 Basel (Switzerland); Ramseyer, J P [National Center of Competence in Research for Nanoscale Science, Institute of Physics of Univesity of Basel, Klingelbergstrasse 82, CH-4056 Basel (Switzerland); Grange, W [National Center of Competence in Research for Nanoscale Science, Institute of Physics of Univesity of Basel, Klingelbergstrasse 82, CH-4056 Basel (Switzerland); Braun, T [National Center of Competence in Research for Nanoscale Science, Institute of Physics of Univesity of Basel, Klingelbergstrasse 82, CH-4056 Basel (Switzerland); Schmid, D [National Center of Competence in Research for Nanoscale Science, Institute of Physics of Univesity of Basel, Klingelbergstrasse 82, CH-4056 Basel (Switzerland); Hunziker, P [National Center of Competence in Research for Nanoscale Science, Institute of Physics of Univesity of Basel, Klingelbergstrasse 82, CH-4056 Basel (Switzerland); Jung, C [National Center of Competence in Research for Nanoscale Science, Institute of Physics of Univesity of Basel, Klingelbergstrasse 82, CH-4056 Basel (Switzerland); Hegner, M [National Center of Competence in Research for Nanoscale Science, Institute of Physics of Univesity of Basel, Klingelbergstrasse 82, CH-4056 Basel (Switzerland); Gerber, C [National Center of Competence in Research for Nanoscale Science, Institute of Physics of Univesity of Basel, Klingelbergstrasse 82, CH-4056 Basel (Switzerland)

    2007-03-15

    We used microfabricated cantilever array sensors for an artificial nose setup. Each cantilever is coated on its top surface with a polymer layer. Volatile gaseous analytes are detected by tracking the diffusion process of the molecules into the polymer layers, resulting in swelling of the polymer layers and therewith bending of the cantilevers. From the bending pattern of all cantilevers in the array, a characteristic 'fingerprint' of the analyte is obtained, which is evaluated using principal component analysis. In a flow of dry nitrogen gas, the bending of the cantilevers is reverted to its initial state before exposure to the analyte, which allows reversible and reproducible operation of the sensor. We show examples of detection of solvents, perfume essences and beverage flavors. In a medical application, the setup provides indication of presence of diseases in patient's breath samples.

  20. Industrial Applications of Electronic Nose Technology in the Textiles Industry

    Science.gov (United States)

    Gibson, Tim; Chandler, Rob; Hallam, Viv; Simpson, Claire; Bentham, Martin

    2009-05-01

    Electronic nose technology has been available commercially for over 12 years but uptake in actual industrial applications has yet to be fully realised. We report 2 specific test protocols being used in the textiles industry that allow the direct measurement of anti-odour and anti-microbial capabilities of fabrics. Results will be shown for the standard anti-odour test which was specifically commissioned by Courtaulds PLC and which is being used by a number of manufacturers. The second test, which measures the anti-microbial and the anti-odour capabilities of fabrics simultaneously was developed in 2008. Results will be shown that clearly indicate both parameters are detected and proofs of anti-microbial capabilities will be given. These 2 tests will for the first time, enable the fulfillment of legislation that states for textile product claims, anti-odour and anti-microbial capabilities of fabrics must be scientifically substantiated.

  1. Electronic Nose To Detect Patients with COPD From Exhaled Breath

    Science.gov (United States)

    Velásquez, Adriana; Durán, Cristhian M.; Gualdron, Oscar; Rodríguez, Juan C.; Manjarres, Leonardo

    2009-05-01

    To date, there is no effective tool analysis and detection of COPD syndrome, (Chronic Obstructive Pulmonary Disease) which is linked to smoking and, less frequently to toxic substances such as, the wood smoke or other particles produced by noxious gases. According to the World Health Organization (WHO) estimates of this disease show it affects more than 52 million people and kills more than 2.7 million human beings each year. In order to solve the problem, a low-cost Electronic Nose (EN) was developed at the University of Pamplona (N. S) Colombia, for this specific purpose and was applied to a sample group of patients with COPD as well as to others who were healthy. From the exhalation breath samples of these patients, the results were as expected; an appropriate classification of the patients with the disease, as well as from the healthy group was obtained.

  2. Electronic Nose For Measuring Wine Evolution In Wine Cellars

    Science.gov (United States)

    Lozano, J.; Santos, J. P.; Horrillo, M. C.; Cabellos, J. M.; Arroyo, T.

    2009-05-01

    An electronic nose installed in a wine cellar for measuring the wine evolution is presented in this paper. The system extract the aroma directly from the tanks where wine is stored and carry the volatile compounds to the sensors cell. A tin oxide multisensor, prepared with RF sputtering onto an alumina substrate and doped with chromium and indium, is used. The whole system is fully automated and controlled by computer and can be supervised by internet. Linear techniques like principal component analysis (PCA) and nonlinear ones like probabilistic neural networks (PNN) are used for pattern recognition. Results show that system can detect the evolution of two different wines along 9 months stored in tanks. This system could be trained to detect off-odours of wine and warn the wine expert to correct it as soon as possible, improving the final quality of wine.

  3. Electronic Nose for Microbiological Quality Control of Food Products

    Directory of Open Access Journals (Sweden)

    M. Falasconi

    2012-01-01

    Full Text Available Electronic noses (ENs have recently emerged as valuable candidates in various areas of food quality control and traceability, including microbial contamination diagnosis. In this paper, the EN technology for microbiological screening of food products is reviewed. Four paradigmatic and diverse case studies are presented: (a Alicyclobacillus spp. spoilage of fruit juices, (b early detection of microbial contamination in processed tomatoes, (c screening of fungal and fumonisin contamination of maize grains, and (d fungal contamination on green coffee beans. Despite many successful results, the high intrinsic variability of food samples together with persisting limits of the sensor technology still impairs ENs trustful applications at the industrial scale. Both advantages and drawbacks of sensor technology in food quality control are discussed. Finally, recent trends and future directions are illustrated.

  4. Histopathologic criteria to confirm white-nose syndrome in bats

    Science.gov (United States)

    Meteyer, C.U.; Buckles, E.L.; Blehert, D.S.; Hicks, A.C.; Green, D.E.; Shearn-Bochsler, V.; Thomas, N.J.; Gargas, A.; Behr, M.J.

    2009-01-01

    White-nose syndrome (WNS) is a cutaneous fungal disease of hibernating bats associated with a novel Geomyces sp. fungus. Currently, confirmation of WNS requires histopathologic examination. Invasion of living tissue distinguishes this fungal infection from those caused by conventional transmissible dermatophytes. Although fungal hyphae penetrate the connective tissue of glabrous skin and muzzle, there is typically no cellular inflammatory response in hibernating bats. Preferred tissue samples to diagnose this fungal infection are rostral muzzle with nose and wing membrane fixed in 10% neutral buffered formalin. To optimize detection, the muzzle is trimmed longitudinally, the wing membrane is rolled, and multiple cross-sections are embedded to increase the surface area examined. Periodic acid-Schiff stain is essential to discriminate the nonpigmented fungal hyphae and conidia. Fungal hyphae form cup-like epidermal erosions and ulcers in the wing membrane and pinna with involvement of underlying connective tissue. In addition, fungal hyphae are present in hair follicles and in sebaceous and apocrine glands of the muzzle with invasion of tissue surrounding adnexa. Fungal hyphae in tissues are branching and septate, but the diameter and shape of the hyphae may vary from parallel walls measuring 2 ??m in diameter to irregular walls measuring 3-5 ??m in diameter. When present on short aerial hyphae, curved conidia are approximately 2.5 ??m wide and 7.5 ??m in curved length. Conidia have a more deeply basophilic center, and one or both ends are usually blunt. Although WNS is a disease of hibernating bats, severe wing damage due to fungal hyphae may be seen in bats that have recently emerged from hibernation. These recently emerged bats also have a robust suppurative inflammatory response.

  5. Resolution of smooth group actions

    CERN Document Server

    Albin, Pierre

    2010-01-01

    A refined form of the `Folk Theorem' that a smooth action by a compact Lie group can be (canonically) resolved, by iterated blow up, to have unique isotropy type is proved in the context of manifolds with corners. This procedure is shown to capture the simultaneous resolution of all isotropy types in a `resolution structure' consisting of equivariant iterated fibrations of the boundary faces. This structure projects to give a similar resolution structure for the quotient. In particular these results apply to give a canonical resolution of the radial compactification, to a ball, of any finite dimensional representation of a compact Lie group; such resolutions of the normal action of the isotropy groups appear in the boundary fibers in the general case.

  6. Smooth ergodic theory for endomorphisms

    CERN Document Server

    Qian, Min; Zhu, Shu

    2009-01-01

    This volume presents a general smooth ergodic theory for deterministic dynamical systems generated by non-invertible endomorphisms, mainly concerning the relations between entropy, Lyapunov exponents and dimensions. The authors make extensive use of the combination of the inverse limit space technique and the techniques developed to tackle random dynamical systems. The most interesting results in this book are (1) the equivalence between the SRB property and Pesin’s entropy formula; (2) the generalized Ledrappier-Young entropy formula; (3) exact-dimensionality for weakly hyperbolic diffeomorphisms and for expanding maps. The proof of the exact-dimensionality for weakly hyperbolic diffeomorphisms seems more accessible than that of Barreira et al. It also inspires the authors to argue to what extent the famous Eckmann-Ruelle conjecture and many other classical results for diffeomorphisms and for flows hold true. After a careful reading of the book, one can systematically learn the Pesin theory for endomorphis...

  7. Learning Smooth Pattern Transformation Manifolds

    CERN Document Server

    Vural, Elif

    2011-01-01

    Manifold models provide low-dimensional representations that are useful for processing and analyzing data in a transformation-invariant way. In this paper, we study the problem of learning smooth pattern transformation manifolds from image sets that represent observations of geometrically transformed signals. In order to construct a manifold, we build a representative pattern whose transformations accurately fit various input images. We examine two objectives of the manifold building problem, namely, approximation and classification. For the approximation problem, we propose a greedy method that constructs a representative pattern by selecting analytic atoms from a continuous dictionary manifold. We present a DC (Difference-of-Convex) optimization scheme that is applicable to a wide range of transformation and dictionary models, and demonstrate its application to transformation manifolds generated by rotation, translation and anisotropic scaling of a reference pattern. Then, we generalize this approach to a s...

  8. Cervical spinal canal narrowing in idiopathic syringomyelia

    Energy Technology Data Exchange (ETDEWEB)

    Struck, Aaron F. [Massachusetts General Hospital, Department of Neurology, Boston, MA (United States); Carr, Carrie M. [Mayo Clinic, Department of Radiology, Rochester, MN (United States); Shah, Vinil [University of California San Francisco, Department of Radiology, San Francisco, CA (United States); Hesselink, John R. [University of California San Diego, Department of Radiology, San Diego, CA (United States); Haughton, Victor M. [University of Wisconsin, Department of Radiology, Madison, WI (United States)

    2016-08-15

    The cervical spine in Chiari I patient with syringomyelia has significantly different anteroposterior diameters than it does in Chiari I patients without syringomyelia. We tested the hypothesis that patients with idiopathic syringomyelia (IS) also have abnormal cervical spinal canal diameters. The finding in both groups may relate to the pathogenesis of syringomyelia. Local institutional review boards approved this retrospective study. Patients with IS were compared to age-matched controls with normal sagittal spine MR. All subjects had T1-weighted spin-echo (500/20) and T2-weighted fast spin-echo (2000/90) sagittal cervical spine images at 1.5 T. Readers blinded to demographic data and study hypothesis measured anteroposterior diameters at each cervical level. The spinal canal diameters were compared with a Mann-Whitney U test. The overall difference was assessed with a Friedman test. Seventeen subjects were read by two reviewers to assess inter-rater reliability. Fifty IS patients with 50 age-matched controls were studied. IS subjects had one or more syrinxes varying from 1 to 19 spinal segments. Spinal canal diameters narrowed from C1 to C3 and then enlarged from C5 to C7 in both groups. Diameters from C2 to C4 were narrower in the IS group (p < 0.005) than in controls. The ratio of the C3 to the C7 diameters was also smaller (p = 0.004) in IS than controls. Collectively, the spinal canal diameters in the IS were significantly different from controls (Friedman test p < 0.0001). Patients with IS have abnormally narrow upper and mid cervical spinal canal diameters and greater positive tapering between C3 and C7. (orig.)

  9. Microstructure and Mechanical Properties of Narrow Gap Laser-Arc Hybrid Welded 40 mm Thick Mild Steel

    Science.gov (United States)

    Zhang, Chen; Li, Geng; Gao, Ming; Zeng, XiaoYan

    2017-01-01

    Both laser-arc hybrid welding and narrow gap welding have potential for the fabrication of thick sections, but their combination has been seldom studied. In this research, 40 mm thick mild steel was welded by narrow gap laser-arc hybrid welding. A weld with smooth layer transition, free of visible defects, was obtained by nine passes at a 6 mm width narrow gap. The lower part of the weld has the lowest mechanical properties because of the lowest amount of acicular ferrite, but its ultimate tensile strength and impact absorbing energy is still 49% and 60% higher than those of base metal, respectively. The microhardness deviation of all filler layers along weld thickness direction is no more than 15 HV0.2, indicating that no temper softening appeared during multiple heat cycles. The results provide an alternative technique for improving the efficiency and quality of welding thick sections. PMID:28772469

  10. Microstructure and Mechanical Properties of Narrow Gap Laser-Arc Hybrid Welded 40 mm Thick Mild Steel

    Directory of Open Access Journals (Sweden)

    Chen Zhang

    2017-01-01

    Full Text Available Both laser-arc hybrid welding and narrow gap welding have potential for the fabrication of thick sections, but their combination has been seldom studied. In this research, 40 mm thick mild steel was welded by narrow gap laser-arc hybrid welding. A weld with smooth layer transition, free of visible defects, was obtained by nine passes at a 6 mm width narrow gap. The lower part of the weld has the lowest mechanical properties because of the lowest amount of acicular ferrite, but its ultimate tensile strength and impact absorbing energy is still 49% and 60% higher than those of base metal, respectively. The microhardness deviation of all filler layers along weld thickness direction is no more than 15 HV0.2, indicating that no temper softening appeared during multiple heat cycles. The results provide an alternative technique for improving the efficiency and quality of welding thick sections.

  11. Smooth halos in the cosmic web

    CERN Document Server

    Gaite, Jose

    2014-01-01

    Dark matter halos can be defined as smooth distributions of dark matter placed in a non-smooth cosmic web structure. This definition of halos demands a precise definition of smoothness and a characterization of the manner in which the transition from smooth halos to the cosmic web takes place. We introduce entropic measures of smoothness, related to measures of equality previously used in economy and with the advantage of being connected with standard methods of multifractal analysis already used for characterizing the cosmic web structure in $N$-body simulations. These entropic measures provide us with a quantitative description of the transition from the small scales portrayed as a distribution of halos to the larger scales portrayed as a cosmic web and, therefore, allow us to assign definite sizes to halos. However, these "smoothness sizes" have no direct relation to the virial radii.

  12. Global viscous overstabilities in narrow rings

    Science.gov (United States)

    Longaretti, Pierre-Yves; French, Richard G.; Nicholson, Philip D.

    2016-10-01

    Local viscous overstabilities have been the focus of a number of theoretical analyses in the last decades due to the rôle they are believed to play in the creation of the small scale structure of broad ring systems (Saturn, Uranus). Global viscous overstabilities have also been investigated in the 1980s and 1990s as a potential source of narrow ring eccentricities (Longaretti and Rappaport, 1995, Icarus, 116, 376).An important feature of global viscous overstabilities is that they produce slow relative librating or circulating motions of narrow ring edges; they may also produce slowly librating or circulating components of edge modes. This process is potentially relevant to explain the occurrence of unusually large apsidal shifts observed in some saturnian ringlets and may also explain the existence of the free m=2 B ring edge mode that is slowly circulating with respect to the component forced by Mimas.The time-scale of such motions is primarily controlled by the ring self-gravity and can be analytically quantified in a two-streamline analysis which yields a characteristic libration/circulation frequency Ωl = (n/π)(Mr/Mp)(a/δa)2H(q2) where n is the mean motion, Mr the ringlet or pertubed region mass, Mp the planet mass, a the semi-major axis, δa the narrow ringlet or pertubed region width and H(q2) a dimensionless factor of order unity that depends on the streamline compression parameter q. The related time-scale is of the order of a few years to a few tens of years depending on the surface density and ringlet/perturbed region geometry. Preliminary data analyzes indicate that the Maxwell and Huyghens ringlets are probably librating with periods consistent with this two-streamline estimate.The talk will briefly present the physics of global viscous overstabilities as well as more detailed applications to narrow rings, and if time permits, to edge modes.

  13. Depicting the inner and outer nose: the representation of the nose and the nasal mucosa on the human primary somatosensory cortex (SI).

    Science.gov (United States)

    Gastl, Mareike; Brünner, Yvonne F; Wiesmann, Martin; Freiherr, Jessica

    2014-09-01

    The nose is important not only for breathing, filtering air, and perceiving olfactory stimuli. Although the face and hands have been mapped, the representation of the internal and external surface of the nose on the primary somatosensory cortex (SI) is still poorly understood. To fill this gap functional magnetic resonance imaging (fMRI) was used to localize the nose and the nasal mucosa in the Brodman areas (BAs) 3b, 1, and 2 of the human postcentral gyrus (PG). Tactile stimulation during fMRI was applied via a customized pneumatically driven device to six stimulation sites: the alar wing of the nose, the lateral nasal mucosa, and the hand (serving as a reference area) on the left and right side of the body. Individual representations could be discriminated for the left and right hand, for the left nasal mucosa and left alar wing of the nose in BA 3b and BA 1 by comparing mean activation maxima and Euclidean distances. Right-sided nasal conditions and conditions in BA 2 could further be separated by different Euclidean distances. Regarding the alar wing of the nose, the results concurred with the classic sensory homunculus proposed by Penfield and colleagues. The nasal mucosa was not only determined an individual and bilateral representation, its position on the somatosensory cortex is also situated closer to the caudal end of the PG compared to that of the alar wing of the nose and the hand. As SI is commonly activated during the perception of odors, these findings underscore the importance of the knowledge of the representation of the nasal mucosa on the primary somatosensory cortex, especially for interpretation of results of functional imaging studies about the sense of smell.

  14. Smooth GERBS, orthogonal systems and energy minimization

    Science.gov (United States)

    Dechevsky, Lubomir T.; Zanaty, Peter

    2013-12-01

    New results are obtained in three mutually related directions of the rapidly developing theory of generalized expo-rational B-splines (GERBS) [7, 6]: closed-form computability of C∞-smooth GERBS in terms of elementary and special functions, Hermite interpolation and least-squares best approximation via smooth GERBS, energy minimizing properties of smooth GERBS similar to those of the classical cubic polynomial B-splines.

  15. Smooth Crossed Products of Rieffel's Deformations

    Science.gov (United States)

    Neshveyev, Sergey

    2014-03-01

    Assume is a Fréchet algebra equipped with a smooth isometric action of a vector group V, and consider Rieffel's deformation of . We construct an explicit isomorphism between the smooth crossed products and . When combined with the Elliott-Natsume-Nest isomorphism, this immediately implies that the periodic cyclic cohomology is invariant under deformation. Specializing to the case of smooth subalgebras of C*-algebras, we also get a simple proof of equivalence of Rieffel's and Kasprzak's approaches to deformation.

  16. Airway Epithelium Stimulates Smooth Muscle Proliferation

    OpenAIRE

    Malavia, Nikita K.; Raub, Christopher B.; Mahon, Sari B.; Brenner, Matthew; Reynold A Panettieri; George, Steven C.

    2009-01-01

    Communication between the airway epithelium and stroma is evident during embryogenesis, and both epithelial shedding and increased smooth muscle proliferation are features of airway remodeling. Hence, we hypothesized that after injury the airway epithelium could modulate airway smooth muscle proliferation. Fully differentiated primary normal human bronchial epithelial (NHBE) cells at an air–liquid interface were co-cultured with serum-deprived normal primary human airway smooth muscle cells (...

  17. Properties of the extremal infinite smooth words

    Directory of Open Access Journals (Sweden)

    Srecko Brlek

    2007-05-01

    Full Text Available Smooth words are connected to the Kolakoski sequence. We construct the maximal and the minimal infinite smooth words, with respect to the lexicographical order. The naive algorithm generating them is improved by using a reduction of the De Bruijn graph of their factors. We also study their Lyndon factorizations. Finally, we show that the minimal smooth word over the alphabet {1,3} belongs to the orbit of the Fibonacci word.

  18. Mimicking the human smell sensing mechanism with an artificial nose platform.

    Science.gov (United States)

    Lee, Sang Hun; Kwon, Oh Seok; Song, Hyun Seok; Park, Seon Joo; Sung, Jong Hwan; Jang, Jyongsik; Park, Tai Hyun

    2012-02-01

    Sensing smell is a highly complex biological process, and characterizing and mimicking the interaction between the olfactory receptor (OR) protein and its ligands is extremely challenging. Herein, we report a highly sensitive and selective human nose-like nanobioelectronic nose (nbe-nose), which responds to gaseous odorants sensitively and selectively, has a signal specificity pattern similar to that in the cellular signal transduction pathway, and maintains an antagonistic behavior similar to the human nose. The human olfaction mechanism was mimicked by using carboxylated polypyrrole nanotubes (CPNTs) functionalized with human OR protein. The nbe-nose was able to detect gaseous odorants at a concentration as low as 0.02 parts-per-trillion (ppt), which was comparable to a highly trained, human expert's nose. The nbe-nose can be used scientifically for smell mechanism studies. It can be also applied to various fields that rely on smell monitoring for industrial and public purposes. Copyright © 2011 Elsevier Ltd. All rights reserved.

  19. Using an Electronic Nose to Rapidly Assess Grandlure Content in Boll Weevil Pheromone Lures

    Institute of Scientific and Technical Information of China (English)

    Charles P.-C. Suh; Ningye Ding; Yubin Lan

    2011-01-01

    Samples of pheromone lures used in boll weevil,Anthonomus grandis (Boheman),eradication programs are routinely analyzed by Gas Chromatography (GC) to ensure lures are adequately dosed with grandlure,the synthetic aggregation pheromone produced by male weevils.However,preparation of GC samples is tedious,time consuming,and requires a moderate level of experience.We examined the use of a commercially-available electronic nose (e-nose) for rapidly assessing the grandlure contents of lures.The e-nose was trained to recognize headspace collections of grandlure emitted from new lures and after lures were aged under field conditions for 4 d,7 d,10 d,and 14 d.Based on cross-validation of the training set,the e-nose was 82%accurate in discriminating among the different age classes of lures.Upon sampling headspace collections of pheromone from a different set of field-aged lures,the e-nose was <50% accurate in discriminating 4 d,7 d,and 10 d aged lures from the other ageclasses of lures.However,the e-nose identified new and 14 d aged lure samples with 100% accuracy.In light of these findings,e-nose technology shows considerable promise as an alternative approach for rapidly assessing the initial grandlure contents of lures used in boll weevil eradication programs.

  20. Smoothing techniques for macromolecular global optimization

    Energy Technology Data Exchange (ETDEWEB)

    More, J.J.; Wu, Zhijun

    1995-09-01

    We study global optimization problems that arise in macromolecular modeling, and the solution of these problems via continuation and smoothing. Our results unify and extend the theory associated with the use of the Gaussian transform for smoothing. We show that the, Gaussian transform can be viewed as a special case of a generalized transform and that these generalized transforms share many of the properties of the Gaussian transform. We also show that the smoothing behavior of the generalized transform can be studied in terms of the Fourier transform and that these results indicate that the Gaussian transform has superior smoothing properties.

  1. A methodology to enlarge narrow stability windows

    Energy Technology Data Exchange (ETDEWEB)

    Araujo, Ewerton M.P.; Pastor, Jorge A.S.C.; Fontoura, Sergio A.B. [Pontificia Univ. Catolica do Rio de Janeiro (PUC-Rio), RJ (Brazil). Dept. de Engenharia Civil. Grupo de Tecnologia e Engenharia de Petroleo

    2004-07-01

    The stability window in a wellbore design is defined by the difference between fracture pressure and collapse pressure. Deep water environments typically present narrow stability windows, because rocks have low strength due to under-compaction process. Often also, horizontal wells are drilled to obtain a better development of reservoirs placed in thin layers of sandstone. In this scenario, several challenges are faced when drilling in deep water. The traditional approach for predicting instabilities is to determine collapses and fractures at borehole wall. However, the initiation of rupture does not indicate that the borehole fails to perform its function as a wellbore. Thus, a methodology in which the stability window may be enlarged is desirable. This paper presents one practical analytical methodology that consists in allowing wellbore pressures smaller than the conventional collapse pressure, i.e., based upon failure on the borehole wall. This means that a collapse region (shear failure) will be developed around the borehole wall. This collapse region is pre-defined and to estimate its size is used a failure criterion. The aforementioned methodology is implemented in a user-friendly software, which can perform analyses of stress, pore pressure, formation failure, mud weight and mud salinity design for drilling in shale formations. Simulations of a wellbore drilling in a narrow stability window environment are performed to demonstrate the improvements of using the methodology. (author)

  2. Cluster headache or narrow angle glaucoma?

    Directory of Open Access Journals (Sweden)

    Prasad Palimar

    1991-01-01

    Full Text Available A 47 year old man with episodes of attacks of pain, redness and mild blurring of vision was investigated for narrow angle glaucoma in view of shallow anterior chambers and a cupped optic disc. The history was reviewed following a spontaneous attack in hospital, which had features other than acute glaucoma. A diagnosis of cluster headache was made on the basis of tests. Cluster headache has been defined as unilateral intense pain, involving the eye and head on one side, usually associated with flushing, nasal congestion and lacrimation; the attacks recurring one or more times daily and lasting 20 - 120 minutes. Such attacks commonly continue for weeks or months and are separated by an asymptomatic period of months to years. This episodic nature, together with unilaterality and tendency to occur at night, closely mimics narrow angle glaucoma. Further, if patients have shallow anterior chambers and disc cupping, the differentiation becomes more difficult yet critical. Resource to provocative tests is often the only answer as the following case report demonstrates.

  3. The Narrow Line Region of Ark 564

    CERN Document Server

    Contini, M; Viegas, S M M; Contini, Marcella; Rodriguez-Ardila, Alberto; Viegas, Sueli

    2003-01-01

    The continuum and emission-line spectrum of the narrow-line Seyfert 1 galaxy Ark 564 is used to investigate, for the first time, the physical conditions and structure of its narrow line region (NLR). For this purpose, composite models, accounting for the coupled effect of photoionization and shocks, are employed. The emission-line spectrum of Ark 564, which ranges from the ultraviolet to the near-infrared, shows a rich forbidden line spectrum. Strong emphasis is given to the study of the coronal line region. The diversity of physical conditions deduced from the observations requires multi-cloud models to reproduce the observed lines and continuum. We find that a combination of high velocity (Vs = 1500 km/s) shock-dominated clouds as well as low velocity (Vs = 150 km/s) radiation-dominated clouds explains the coronal lines, while the optical low-ionization lines are mainly explained by shock-dominated clouds. The results for Ark 564 are compared with those obtained for other Seyfert galaxies previously analyze...

  4. Analytic solutions of tunneling time through smooth barriers

    Science.gov (United States)

    Xiao, Zhi; Huang, Hai

    2016-03-01

    In the discussion of temporary behaviors of quantum tunneling, people usually like to focus their attention on rectangular barrier with steep edges, or to deal with smooth barrier with semi-classical or even numerical calculations. Very few discussions on analytic solutions of tunneling through smooth barrier appear in the literature. In this paper, we provide two such examples, a semi-infinite long barrier V ( x ) = /A 2 [ 1 + tanh ( x / a ) ] and a finite barrier V(x) = A sech2(x/a). To each barrier, we calculate the associated phase time and dwell time after obtaining the analytic solution. The results show that, different from rectangular barrier, phase time or dwell time does increase with the length parameter a controlling the effective extension of the barrier. More interestingly, for the finite barrier, phase time or dwell time exhibits a peak in k-space. A detailed analysis shows that this interesting behavior can be attributed to the strange tunneling probability Ts(k), i.e., Ts(k) displays a unit step function-like profile Θ(k - k0), especially when a is large, say, a ≫ 1/κ, 1/k. And k 0 ≡ √{ m A } / ħ is exactly where the peak appears in phase or dwell time k-spectrum. Thus only those particles with k in a very narrow interval around k0 are capable to dwell in the central region of the barrier sufficiently long.

  5. Multi-scale model of epidemic fade-out: Will local extirpation events inhibit the spread of white-nose syndrome?

    Science.gov (United States)

    O'Reagan, Suzanne M; Magori, Krisztian; Pulliam, J Tomlin; Zokan, Marcus A; Kaul, RajReni B; Barton, Heather D; Drake, John M

    2015-04-01

    White-nose syndrome (WNS) is an emerging infectious disease that has resulted in severe declines of its hibernating bat hosts in North America. The ongoing epidemic of white-nose syndrome is a multi-scale phenomenon becau.se it causes hibernaculum-level extirpations, while simultaneously spreading over larger spatial scales. We investigate a neglected topic in ecological epidemiology: how local pathogen-driven extirpations impact large-scale pathogen spread. Previous studies have identified risk factors for propagation of WNS over hibernaculum and landscape scales but none of these have tested the hypothesis that separation of spatial scales and disease-induced mortality at the hibernaculum level might slow or halt its spread. To test this hypothesis, we developed a mechanistic multi-scale model parameterized using white-nose syndrome.county and site incidence data that connects hibernaculum-level susceptible-infectious-removed (SIR) epidemiology to the county-scale contagion process. Our key result is that hibernaculum-level extirpations will not inhibit county-scale spread of WNS. We show that over 80% of counties of the contiguous USA are likely to become infected before the current epidemic is over and that geometry of habitat connectivity is such that host refuges are exceedingly rare. The macroscale spatiotemporal infection pattern that emerges from local SIR epidemiological processes falls within a narrow spectrum of possible outcomes, suggesting that recolonization, rescue effects, and multi-host complexities at local scales are not important to forward propagation of WNS at large spatial scales. If effective control measures are not implemented, precipitous declines in bat populations are likely, particularly in cave-dense regions that constitute the main geographic corridors of the USA, a serious concern for bat conservation.

  6. Hump-nosed viper bite: an important but under-recognized cause of systemic envenoming.

    Science.gov (United States)

    Shivanthan, Mitrakrishnan Chrishan; Yudhishdran, Jevon; Navinan, Rayno; Rajapakse, Senaka

    2014-01-01

    Hump-nosed viper bites are common in the Indian subcontinent. In the past, hump-nosed vipers (Hypnale species) were considered moderately venomous snakes whose bites result mainly in local envenoming. However, a variety of severe local effects, hemostatic dysfunction, microangiopathic hemolysis, kidney injury and death have been reported following envenoming by Hypnale species. We systematically reviewed the medical literature on the epidemiology, toxin profile, diagnosis, and clinical, laboratory and postmortem features of hump-nosed viper envenoming, and highlight the need for development of an effective antivenom.

  7. Development of narrow gap welding technology for extremely thick steel

    Science.gov (United States)

    Imai, K.; Saito, T.; Okumura, M.

    In the field of extremely thick steel, various narrow gap welding methods were developed on the basis of former welding methods and are used in practice. It is important to develop and improve automatic narrow gap welding, J edge preparation by gas cutting, the prevention of welding defects, wires for narrow gap welding and so on in order to expand the scope of application of the method. Narrow gap welding technologies are described, based on new concepts developed by Nippon Steel Corporation.

  8. Promoting L2 Vocabulary Learning through Narrow Reading

    Science.gov (United States)

    Kang, Eun Young

    2015-01-01

    Krashen (2004) has advocated that narrow reading, i.e., reading a series of texts addressing one specific topic, is an effective method to grow vocabulary. While narrow reading has been championed to have many advantages for L2 vocabulary learning, there remains a relative dearth of empirical studies that test the impact of narrow reading on L2…

  9. Aeroacoustic characterization of scaled canonical nose landing gear configurations

    Science.gov (United States)

    Zawodny, Nikolas S.

    Aircraft noise is a critical issue in the commercial airline industry. Airframe noise is a subcomponent of aircraft noise and is generally dominant over jet engine noise during approach conditions, which can lead to high community impact. Landing gears have been identified as major components of airframe noise during landing configurations for commercial aircraft. They are perhaps the least understood contributors to airframe noise due to complex flow patterns associated with intricate gear component geometries. Nose landing gear in particular have received much attention in recent years, exhibiting acoustic signatures on the order of the main landing gear assembly of an aircraft, while simultaneously being more amenable to scaled wind tunnel testing. In order to characterize the acoustic signature of a complex geometry such as a nose landing gear, it is important to isolate, study, and understand the acoustic contributions of individual component geometries. The purpose of this dissertation is to develop a correlation between the complex flow field nature and far-field acoustic signature of a nose landing gear sub-system. The model under investigation is a 1/2-scale shock-strut cylinder coupled with an adjustable torque link apparatus. This geometry was chosen due to its fundamental importance and implementation across a wide span of commercial aircraft. The fluid dynamic (surface pressure and stereoscopic particle image velocimety) and aeroacoustic (far-field microphone and phased array) experiments were performed in the University of Florida Aeroacoustic Flow Facility. The experimental data compare favorably with the results of a numerical simulation using PowerFLOW, a lattice-Boltzmann solver developed by the Exa Corporation. The far-field acoustic results of this dissertation have shown non-uniform scaling behavior as a function of frequency for the different model configurations tested. For frequencies that appropriately satisfied the condition of acoustic

  10. Smooth horizons and quantum ripples

    CERN Document Server

    Golovnev, Alexey

    2014-01-01

    Black Holes are unique objects which allow for meaningful theoretical studies of strong gravity and even quantum gravity effects. An infalling and a distant observer would have very different views on the structure of the world. However, a careful analysis has shown that it entails no genuine contradictions for physics, and the paradigm of observer complementarity has been coined. Recently this picture was put into doubt. In particular, it was argued that in old Black Holes a firewall must form in order to protect the basic principles of quantum mechanics. This AMPS paradox has already been discussed in a vast number of papers with different attitudes and conclusions. Here we want to argue that a possible source of confusion is neglection of quantum gravity effects. Contrary to widespread perception, it does not necessarily mean that effective field theory is inapplicable in rather smooth neighbourhoods of large Black Hole horizons. The real offender might be an attempt to consistently use it over the huge di...

  11. Local Transfer Coefficient, Smooth Channel

    Directory of Open Access Journals (Sweden)

    R. T. Kukreja

    1998-01-01

    Full Text Available Naphthalene sublimation technique and the heat/mass transfer analogy are used to determine the detailed local heat/mass transfer distributions on the leading and trailing walls of a twopass square channel with smooth walls that rotates about a perpendicular axis. Since the variation of density is small in the flow through the channel, buoyancy effect is negligible. Results show that, in both the stationary and rotating channel cases, very large spanwise variations of the mass transfer exist in he turn and in the region immediately downstream of the turn in the second straight pass. In the first straight pass, the rotation-induced Coriolis forces reduce the mass transfer on the leading wall and increase the mass transfer on the trailing wall. In the turn, rotation significantly increases the mass transfer on the leading wall, especially in the upstream half of the turn. Rotation also increases the mass transfer on the trailing wall, more in the downstream half of the turn than in the upstream half of the turn. Immediately downstream of the turn, rotation causes the mass transfer to be much higher on the trailing wall near the downstream corner of the tip of the inner wall than on the opposite leading wall. The mass transfer in the second pass is higher on the leading wall than on the trailing wall. A slower flow causes higher mass transfer enhancement in the turn on both the leading and trailing walls.

  12. Smooth horizons and quantum ripples

    Energy Technology Data Exchange (ETDEWEB)

    Golovnev, Alexey [Saint Petersburg State University, High Energy Physics Department, Saint-Petersburg (Russian Federation)

    2015-05-15

    Black holes are unique objects which allow for meaningful theoretical studies of strong gravity and even quantum gravity effects. An infalling and a distant observer would have very different views on the structure of the world. However, a careful analysis has shown that it entails no genuine contradictions for physics, and the paradigm of observer complementarity has been coined. Recently this picture was put into doubt. In particular, it was argued that in old black holes a firewall must form in order to protect the basic principles of quantum mechanics. This AMPS paradox has already been discussed in a vast number of papers with different attitudes and conclusions. Here we want to argue that a possible source of confusion is the neglect of quantum gravity effects. Contrary to widespread perception, it does not necessarily mean that effective field theory is inapplicable in rather smooth neighbourhoods of large black hole horizons. The real offender might be an attempt to consistently use it over the huge distances from the near-horizon zone of old black holes to the early radiation. We give simple estimates to support this viewpoint and show how the Page time and (somewhat more speculative) scrambling time do appear. (orig.)

  13. Smoothed particle hydrodynamics and magnetohydrodynamics

    Science.gov (United States)

    Price, Daniel J.

    2012-02-01

    This paper presents an overview and introduction to smoothed particle hydrodynamics and magnetohydrodynamics in theory and in practice. Firstly, we give a basic grounding in the fundamentals of SPH, showing how the equations of motion and energy can be self-consistently derived from the density estimate. We then show how to interpret these equations using the basic SPH interpolation formulae and highlight the subtle difference in approach between SPH and other particle methods. In doing so, we also critique several 'urban myths' regarding SPH, in particular the idea that one can simply increase the 'neighbour number' more slowly than the total number of particles in order to obtain convergence. We also discuss the origin of numerical instabilities such as the pairing and tensile instabilities. Finally, we give practical advice on how to resolve three of the main issues with SPMHD: removing the tensile instability, formulating dissipative terms for MHD shocks and enforcing the divergence constraint on the particles, and we give the current status of developments in this area. Accompanying the paper is the first public release of the NDSPMHD SPH code, a 1, 2 and 3 dimensional code designed as a testbed for SPH/SPMHD algorithms that can be used to test many of the ideas and used to run all of the numerical examples contained in the paper.

  14. NDSPMHD Smoothed Particle Magnetohydrodynamics Code

    Science.gov (United States)

    Price, Daniel J.

    2011-01-01

    This paper presents an overview and introduction to Smoothed Particle Hydrodynamics and Magnetohydrodynamics in theory and in practice. Firstly, we give a basic grounding in the fundamentals of SPH, showing how the equations of motion and energy can be self-consistently derived from the density estimate. We then show how to interpret these equations using the basic SPH interpolation formulae and highlight the subtle difference in approach between SPH and other particle methods. In doing so, we also critique several 'urban myths' regarding SPH, in particular the idea that one can simply increase the 'neighbour number' more slowly than the total number of particles in order to obtain convergence. We also discuss the origin of numerical instabilities such as the pairing and tensile instabilities. Finally, we give practical advice on how to resolve three of the main issues with SPMHD: removing the tensile instability, formulating dissipative terms for MHD shocks and enforcing the divergence constraint on the particles, and we give the current status of developments in this area. Accompanying the paper is the first public release of the NDSPMHD SPH code, a 1, 2 and 3 dimensional code designed as a testbed for SPH/SPMHD algorithms that can be used to test many of the ideas and used to run all of the numerical examples contained in the paper.

  15. Smoothing a Piecewise-Smooth: An Example from Plankton Population Dynamics

    DEFF Research Database (Denmark)

    Piltz, Sofia Helena

    2016-01-01

    In this work we discuss a piecewise-smooth dynamical system inspired by plankton observations and constructed for one predator switching its diet between two different types of prey. We then discuss two smooth formulations of the piecewise-smooth model obtained by using a hyperbolic tangent...

  16. The Narrow Line Region of Narrow-Line Seyfert 1 Galaxies

    CERN Document Server

    Rodríguez-Ardila, A; Pastoriza, M G; Donzelli, C J

    2000-01-01

    This work studies the optical emission line properties and physical conditions of the narrow line region (NLR) of seven narrow-line Seyfert 1 galaxies (NLS1). Our results show that the flux carried out by the narrow component of H-beta is, on average, 50% of the total line flux. As a result, the [OIII] 5007/H-beta ratio emitted in the NLR varies from 1 to 5, instead of the universally adopted value of 10. This has strong implications for the required spectral energy distribution that ionizes the NLR gas. Photoionization models that consider a NLR composed of a combination of matter-bounded and ionization-bounded clouds are successful at explaining the low [OIII] 5007/H-beta ratio and the weakness of low-ionization lines of NLS1s. Variation of the relative proportion of these two type of clouds nicely reproduce the dispersion of narrow line ratios found among the NLS1 sample. Assuming similar physical model parameters of both NLS1s and the normal Seyfert 1 galaxy NGC 5548, we show that the observed differences...

  17. Thermal smoothing of rough surfaces in vacuo

    Science.gov (United States)

    Wahl, G.

    1986-01-01

    The derivation of equations governing the smoothing of rough surfaces, based on Mullins' (1957, 1960, and 1963) theories of thermal grooving and of capillarity-governed solid surface morphology is presented. As an example, the smoothing of a one-dimensional sine-shaped surface is discussed.

  18. Smoothing the output from a DAC

    Science.gov (United States)

    Wagner, C.

    1980-01-01

    Circuit smooths stepped waveform from analog-to-digital converter without appreciable phase shift between stepped input signal and smoothed output signal and without any effect from stepping rate. Waveform produced is suitable for driving controls used in manufacturing processes, aerospace systems, and automobiles.

  19. Narrow-Bicliques: Cryptanalysis of Full IDEA

    DEFF Research Database (Denmark)

    Khovratovich, D.; Leurent, G.; Rechberger, C.

    2012-01-01

    We apply and extend the recently introduced biclique framework to IDEA and for the first time describe an approach to noticeably speed-up key-recovery for the full 8.5 round IDEA.We also show that the biclique approach to block cipher cryptanalysis not only obtains results on more rounds, but also...... improves time and data complexities over existing attacks. We consider the first 7.5 rounds of IDEA and demonstrate a variant of the approach that works with practical data complexity. The conceptual contribution is the narrow-bicliques technique: the recently introduced independent-biclique approach...... the practical use of IDEA in any way, yet the techniques are practically verified to a large extent....

  20. Robotic chair at steep and narrow stairways

    Science.gov (United States)

    Imazato, Masahiro; Yamaguchi, Masahiro; Moromugi, Shunji; Ishimatsu, Takakazu

    2007-12-01

    A robotic chair is developed to support mobility of elderly and disabled people living in the house where steep and narrow stairways are installed. In order to deal with such mobility problem the developed robotic chair has a compact original configuration. The robotic chair vertically moves by actuation of electric cylinders and horizontally moves by push-pull operation given by a care-giver. In order to navigate safely every action of the chair is checked by the operator. Up-and-down motions of the robotic chair on the stairway are executed through combinations of motor and cylinder actuations. Performance of the robotic chair was evaluated through two kinds of experiments. The excellent ability of the robotic chair could be confirmed through these experiments.

  1. Narrow-angle astrometry with PRIMA

    CERN Document Server

    Sahlmann, J; Mérand, A; Zimmerman, N; Abuter, R; Chazelas, B; Delplancke, F; Henning, T; Kaminski, A; Köhler, R; Launhardt, R; Mohler, M; Pepe, F; Queloz, D; Quirrenbach, A; Reffert, S; Schmid, C; Schuhler, N; Schulze-Hartung, T

    2012-01-01

    The Extrasolar Planet Search with PRIMA project (ESPRI) aims at characterising and detecting extrasolar planets by measuring the host star's reflex motion using the narrow-angle astrometry capability of the PRIMA facility at the Very Large Telescope Interferometer. A first functional demonstration of the astrometric mode was achieved in early 2011. This marked the start of the astrometric commissioning phase with the purpose of characterising the instrument's performance, which ultimately has to be sufficient for exoplanet detection. We show results obtained from the observation of bright visual binary stars, which serve as test objects to determine the instrument's astrometric precision, its accuracy, and the plate scale. Finally, we report on the current status of the ESPRI project, in view of starting its scientific programme.

  2. Diluted magnetic semiconductors with narrow band gaps

    Science.gov (United States)

    Gu, Bo; Maekawa, Sadamichi

    2016-10-01

    We propose a method to realize diluted magnetic semiconductors (DMSs) with p - and n -type carriers by choosing host semiconductors with a narrow band gap. By employing a combination of the density function theory and quantum Monte Carlo simulation, we demonstrate such semiconductors using Mn-doped BaZn2As2 , which has a band gap of 0.2 eV. In addition, we found a nontoxic DMS Mn-doped BaZn2Sb2 , of which the Curie temperature Tc is predicted to be higher than that of Mn-doped BaZn2As2 , the Tc of which was up to 230 K in a recent experiment.

  3. Tissue characterization by using narrow band imaging

    Science.gov (United States)

    Gono, Kazuhiro

    2010-02-01

    NBI (Narrow Band Imaging) was first introduced in the market in 2005 as a technique enabling to enhance image contrast of capillaries on a mucosal surface(1). It is classified as an Optical-Digital Method for Image-Enhanced Endoscopy(2). To date, the application has widely spread not only to gastrointestinal fields such as esophagus, stomach and colon but also the organs such as bronchus and bladder. The main target tissue of NBI enhancement is capillaries. However, findings of many clinical studies conducted by endoscopy physicians have revealed that NBI observation enables to enhance more other structures in addition to capillaries. There is a close relationship between those enhanced structures and histological microstructure of a tissue. This report introduces the tissue microstructures enhanced by NBI and discusses the possibility of optimized illumination wavelength in observing living tissues.

  4. Smoothed dynamics in the central field problem

    CERN Document Server

    Santoprete, Manuele

    2009-01-01

    Consider the motion of a material point of unit mass in a central field determined by a homogeneous potential of the form $(-1/r^{\\alpha})$, $\\alpha>0,$ where $r$ being the distance to the centre of the field. Due to the singularity at $r=0,$ in computer-based simulations, usually, the potential is replaced by a similar potential that is smooth, or at least continuous. In this paper, we compare the global flows given by the smoothed and non-smoothed potentials. It is shown that the two flows are topologically equivalent for $\\alpha < 2,$ while for $\\alpha \\geq 2,$ smoothing introduces fake orbits. Further, we argue that for $\\alpha\\geq 2,$ smoothing should be applied to the amended potential $c/(2r^2)-1/r^{\\alpha},$ where $c$ denotes the angular momentum constant.

  5. Cursive writing with smooth pursuit eye movements.

    Science.gov (United States)

    Lorenceau, Jean

    2012-08-21

    The eyes never cease to move: ballistic saccades quickly turn the gaze toward peripheral targets, whereas smooth pursuit maintains moving targets on the fovea where visual acuity is best. Despite the oculomotor system being endowed with exquisite motor abilities, any attempt to generate smooth eye movements against a static background results in saccadic eye movements. Although exceptions to this rule have been reported, volitional control over smooth eye movements is at best rudimentary. Here, I introduce a novel, temporally modulated visual display, which, although static, sustains smooth eye movements in arbitrary directions. After brief training, participants gain volitional control over smooth pursuit eye movements and can generate digits, letters, words, or drawings at will. For persons deprived of limb movement, this offers a fast, creative, and personal means of linguistic and emotional expression. Copyright © 2012 Elsevier Ltd. All rights reserved.

  6. Improved Edge Awareness in Discontinuity Preserving Smoothing

    CERN Document Server

    Heinrich, Stuart B

    2011-01-01

    Discontinuity preserving smoothing is a fundamentally important procedure that is useful in a wide variety of image processing contexts. It is directly useful for noise reduction, and frequently used as an intermediate step in higher level algorithms. For example, it can be particularly useful in edge detection and segmentation. Three well known algorithms for discontinuity preserving smoothing are nonlinear anisotropic diffusion, bilateral filtering, and mean shift filtering. Although slight differences make them each better suited to different tasks, all are designed to preserve discontinuities while smoothing. However, none of them satisfy this goal perfectly: they each have exception cases in which smoothing may occur across hard edges. The principal contribution of this paper is the identification of a property we call edge awareness that should be satisfied by any discontinuity preserving smoothing algorithm. This constraint can be incorporated into existing algorithms to improve quality, and usually ha...

  7. The Tool Life of Ball Nose end Mill Depending on the Different Types of Ramping

    Directory of Open Access Journals (Sweden)

    Vopát Tomáš

    2014-12-01

    Full Text Available The article deals with the cutting tool wear measurement process and tool life of ball nose end mill depending on upward ramping and downward ramping. The aim was to determine and compare the wear (tool life of ball nose end mill for different types of copy milling operations, as well as to specify particular steps of the measurement process. In addition, we examined and observed cutter contact areas of ball nose end mill with machined material. For tool life test, DMG DMU 85 monoBLOCK 5-axis CNC milling machine was used. In the experiment, cutting speed, feed rate, axial depth of cut and radial depth of cut were not changed. The cutting tool wear was measured on Zoller Genius 3s universal measuring machine. The results show different tool life of ball nose end mills depending on the copy milling strategy.

  8. Clown nose: a case of disfiguring nodular squamous cell carcinoma of the face.

    Science.gov (United States)

    Colletti, Giacomo; Allevi, Fabiana; Moneghini, Laura; Palvarini, Marina

    2014-01-31

    'Clown nose' (CN) is the common medical term referring to a reddish-brown bulge involving the tip of the nose, reminding of a clown's fake red nose. Reports about these tumours are scarce. Most reports refer to metastatic skin manifestation of systemic malignancies: this condition has been rarely described as a primary skin neoplasm. We report a case of a 31-year-old patient with a giant cutaneous squamous cell carcinoma of the nose which evolved into a CN. After ruling out genetic or immune risk factors, the patient was treated with surgical excision of the lesion and local reconstruction with good aesthetic outcome and no recurrence over a 2-year follow-up.

  9. Electronic nose for quality control of Colombian coffee through the detection of defects in "Cup Tests".

    Science.gov (United States)

    Rodríguez, Juan; Durán, Cristhian; Reyes, Adriana

    2010-01-01

    Electronic noses (ENs), are used for many applications, but we must emphasize the importance of their application to foodstuffs like coffee. This paper presents a research study about the analysis of Colombian coffee samples for the detection and classification of defects (i.e., using "Cup Tests"), which was conducted at the Almacafé quality control laboratory in Cúcuta, Colombia. The results obtained show that the application of an electronic nose called "A-NOSE", may be used in the coffee industry for the cupping tests. The results show that e-nose technology can be a useful tool for quality control to evaluate the excellence of the Colombian coffee produced by National Federation of Coffee Growers.

  10. Evaluation of Maturity and Flavor of Melons Using an Electronic Nose

    Institute of Scientific and Technical Information of China (English)

    TANG Xiao-wei; HE Hong-ju; GENG Li-hua; ZHANG Wan-qing

    2011-01-01

    In this work, an electronic nose was used to evaluate the different cultivars and mature stages of melons, so as to establish a scientific method to accurately distinguish the maturity and varieties of melons.Principal component analysis (PCA) and linear discriminant analysis ( LDA ) showed that immature melons could be well distinguished from mature melons using electronic nose.When PCA method was used to analyze, electronic nose could completely classify and identify the maturity of melons.Meanwhile, the electronic nose could distinguish different varieties of melons with high discrimination value.The flavor of samples under cut or no cut conditions would slightly change, leading to the variation of discrimination value among different varieties.The samples with similar flavor under no cut condition could be analyzed through cutting mode.The research built a rapid and accurate method to judge the maturity of melons instead of man sense.

  11. A novel method for qualitative analysis of edible oil oxidation using an electronic nose.

    Science.gov (United States)

    Xu, Lirong; Yu, Xiuzhu; Liu, Lei; Zhang, Rui

    2016-07-01

    An electronic nose (E-nose) was used for rapid assessment of the degree of oxidation in edible oils. Peroxide and acid values of edible oil samples were analyzed using data obtained by the American Oil Chemists' Society (AOCS) Official Method for reference. Qualitative discrimination between non-oxidized and oxidized oils was conducted using the E-nose technique developed in combination with cluster analysis (CA), principal component analysis (PCA), and linear discriminant analysis (LDA). The results from CA, PCA and LDA indicated that the E-nose technique could be used for differentiation of non-oxidized and oxidized oils. LDA produced slightly better results than CA and PCA. The proposed approach can be used as an alternative to AOCS Official Method as an innovative tool for rapid detection of edible oil oxidation.

  12. The Application of AN Electronic Nose as a Predictive Technique against Human Diabetic Nephropathy

    Science.gov (United States)

    Mohamed, E. I.; Festuccia, A. M.; Martinelli, E.; Andreoli, A.; Martini, A.; di Natale, C.; de Lorenzo, A.

    2000-12-01

    The aim of this study is to apply electronic nose (EN) technology as an alternative method for fast monitoring of metabolic clearances and nephropathy insurgence in diabetics. This will be performed through urine analyses of diabetic patients and healthy subjects.

  13. Final Critical Habitat for the New Mexican ridge-nosed rattlesnake (Crotalus willardi obscurus)

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — To provide the user with a general idea of areas where final critical habitat for New Mexican ridge-nosed rattlesnake (Crotalus willardi obscurus) occur based on the...

  14. Application of electronic nose and electronic tongue in the dairy industry

    Directory of Open Access Journals (Sweden)

    Milna Tudor Kalit

    2014-11-01

    Full Text Available Electronic nose (e-nose and electronic tongue (e-tongue instrumental systems were designed to crudely mimic human olfactory and taste sensory organs and are composed of an array of sensors. Complex data sets from electronic nose and electronic tongue signals combined with multivariate statistics represent rapid and efficient tools for classification, discrimination, recognition and identification of samples, as well as for the prediction of concentrations of different compounds. A wide variety of sensors can be employed into the design of these instrumental systems, especially that of electronic tongues, offering numerous practical applications. In this study, characteristics of sensors and possibilities of electronic nose and electronic tongue applications in the dairy industry were reviewed.

  15. SMACK - SMOOTHING FOR AIRCRAFT KINEMATICS

    Science.gov (United States)

    Bach, R.

    1994-01-01

    The computer program SMACK (SMoothing for AirCraft Kinematics) is designed to provide flightpath reconstruction of aircraft forces and motions from measurements that are noisy or incomplete. Additionally, SMACK provides a check on instrument accuracy and data consistency. The program can be used to analyze data from flight-test experiments prior to their use in performance, stability and control, or aerodynamic modeling calculations. It can also be used in the analysis of aircraft accidents, where the actual forces and motions may have to be determined from a very limited data set. Application of a state-estimation method for flightpath reconstruction is possible because aircraft forces and motions are related by well-known equations of motion. The task of postflight state estimation is known as a nonlinear, fixed-interval smoothing problem. SMACK utilizes a backward-filter, forward-smoother algorithm to solve the problem. The equations of motion are used to produce estimates that are compared with their corresponding measurement time histories. The procedure is iterative, providing improved state estimates until a minimum squared-error measure is achieved. In the SMACK program, the state and measurement models together represent a finite-difference approximation for the six-degree-of-freedom dynamics of a rigid body. The models are used to generate time histories which are likely to be found in a flight-test measurement set. These include onboard variables such as Euler angles, angular rates, and linear accelerations as well as tracking variables such as slant range, bearing, and elevation. Any bias or scale-factor errors associated with the state or measurement models are appended to the state vector and treated as constant but unknown parameters. The SMACK documentation covers the derivation of the solution algorithm, describes the state and measurement models, and presents several application examples that should help the analyst recognize the potential

  16. Automatic Narrow-Deep Feature Recognition for Mould Manufacturing

    Institute of Scientific and Technical Information of China (English)

    Zheng-Ming Chen; Kun-Jin He; Jing Liu

    2011-01-01

    There usually exist narrow-long-deep areas in mould needed to be machined in special machining. To identify the narrow-deep areas automatically, an automatic narrow-deep feature (NF) recognition method is put forward accordingly. First, the narrow-deep feature is defined innovatively in this field and then feature hint is extracted from the mould by the characteristics of narrow-deep feature. Second, the elementary constituent faces (ECF) of a feature are found on the basis of the feature hint. By means of extending and clipping the ECF, the feature faces are obtained incrementally by geometric reasoning. As a result, basic narrow-deep features (BNF) related are combined heuristically. The proposed NF recognition method provides an intelligent connection between CAD and CAPP for machining narrow-deep areas in mould.

  17. Calibration of an electronic nose for poultry farm

    Science.gov (United States)

    Abdullah, A. H.; Shukor, S. A.; Kamis, M. S.; Shakaff, A. Y. M.; Zakaria, A.; Rahim, N. A.; Mamduh, S. M.; Kamarudin, K.; Saad, F. S. A.; Masnan, M. J.; Mustafa, H.

    2017-03-01

    Malodour from the poultry farms could cause air pollution and therefore potentially dangerous to humans' and animals' health. This issue also poses sustainability risk to the poultry industries due to objections from local community. The aim of this paper is to develop and calibrate a cost effective and efficient electronic nose for poultry farm air monitoring. The instrument main components include sensor chamber, array of specific sensors, microcontroller, signal conditioning circuits and wireless sensor networks. The instrument was calibrated to allow classification of different concentrations of main volatile compounds in the poultry farm malodour. The outcome of the process will also confirm the device's reliability prior to being used for poultry farm malodour assessment. The Multivariate Analysis (HCA and KNN) and Artificial Neural Network (ANN) pattern recognition technique was used to process the acquired data. The results show that the instrument is able to calibrate the samples using ANN classification model with high accuracy. The finding verifies the instrument's performance to be used as an effective poultry farm malodour monitoring.

  18. Electronic noses: Powerful tools in meat quality assessment.

    Science.gov (United States)

    Wojnowski, Wojciech; Majchrzak, Tomasz; Dymerski, Tomasz; Gębicki, Jacek; Namieśnik, Jacek

    2017-09-01

    Main factors that are considered by consumers when choosing meat products are colour and aroma, of which the latter is a more reliable indicator of quality. However, a simple sensory evaluation of hedonistic qualities is often not sufficient to determine whether protein is past its shelf life, and consumption of spoiled meat can lead to serious health hazards. Some volatile compounds can be used as spoilage indicators, and so a device equipped with a sensor sensitive to particular odorants would prove useful. Unfortunately, no such single compound has yet been identified, as the changes taking place in a sample of meat during storage are contingent on numerous factors. On the other hand, a combination of volatile compounds may form a unique 'fingerprint' which can be analysed pattern recognition algorithms with an electronic nose. It can supplement established techniques of meat quality assessment by providing results that correlate well with hedonic perception in a short time and at a low cost. Copyright © 2017 Elsevier Ltd. All rights reserved.

  19. Standardising and validating aromatic profile analysis by an electronic nose

    Directory of Open Access Journals (Sweden)

    Carlos Mario Zuluaga

    2011-05-01

    Full Text Available  The electronic nose is one of the most innovative techniques which had been used in the analysis of food and other aroma matrices. This device imitates the human olfactory system through sensors which are partially specific for different groups of volatile chemicals and differentiating and classifying food (by involving multivariate statistics and it is also used for establishing quality and control parameters. Although the technique has been increasingly applied in research and industry, few studies have been published in the scientific literature referring to validating its use as an analytical methodology. This work’s main objective was to standardise and validate the aromatic profile analysis method for differentiating apiculture products: honey, pollen and propolis. Standardisation involved modifying sample preparation and system variables while validation involved analysis of repeatability and intermediate repeatability of the method and establishing its uncertainty. The results showed that it was possible to set suitable operational parameters for each apicultural product while validation data showed that this technique did not reveal significant differences as reliable values were obtained when using this device as an analysis and quality control tool. 

  20. Geographical classification of Chilean wines by an electronic nose

    Directory of Open Access Journals (Sweden)

    Nicolás H Beltrán

    2009-08-01

    Full Text Available Nicolás H Beltrán, Manuel A Duarte-Mermoud, Ricardo E MuñozDepartment of Electrical Engineering, University of Chile, Santiago, ChileAbstract: This paper discusses the classification of Chilean wines by geographical origin based only on aroma information. The varieties of Cabernet Sauvignon, Merlot, and Carménère analyzed here are produced in four different valleys in the central part of Chile (Colchagua, Maipo, Maule, and Rapel. Aroma information was obtained with a zNoseTM (fast gas chromatograph and the data was analyzed by applying wavelet transform for feature extraction followed by an analysis with support vector machines for classification. Two evaluations of the classification technique were performed; the average percentage of correct classification performed on the validation set was obtained by means of cross-validation against the percentage of correct classification obtained on the test set. This developed technique obtained results on classification rates over 94% in both cases. The geographical origin of a Chilean wine can be resolved rapidly with fast gas chromatography and data processing.Keywords: geographical origin, origin denomination, wine classification, pattern recognition, support vector machines, wavelet analysis, feature extraction

  1. Mange epizootic in white-nosed coatis in western Mexico.

    Science.gov (United States)

    Valenzuela, D; Ceballos, G; García, A

    2000-01-01

    From November of 1994 to June of 1996 an epizootic of mange, probably caused by the mite Notoedres cati, occurred in white-nosed coatis (Nasua narica) in the tropical dry forests of the Chamela-Cuixmala Biosphere Reserve in western Mexico. A monitoring scheme to determine the extent and severity of the epizootic within coatis was implemented. Trapping periods and transects were conducted for 2 yr. To control the spread of the disease, all captured infected coatis were either euthanized or treated with acaricides such as Butox and Ivomec-F, depending on the severity of their infection. Four other species of wild mammals and feral cats had skin conditions resembling mange. A more severe problem with the disease was predicted and later confirmed in the less isolated areas of the reserve, with a higher density of coatis. Our results indicate that epizootics may be more prone to occur in areas with greater fragmentation and less isolation from anthropogenic influence. Interestingly, although there was an apparently severe impact of the mange epizootic in the coati population, the long-term impact of the disease is unknown but appears to be negligible. So in order to understand the role of diseases in wildlife populations, long-term experimental studies are required.

  2. Airborne inflammatory factors: "from the nose to the brain".

    Science.gov (United States)

    Tonelli, Leonardo H; Postolache, Teodor T

    2010-01-01

    The intranasal pathway is a direct route of communication between the environment and the brain. This pathway is currently used for the delivery of several experimental therapeutic peptides and vaccines because it bypasses the blood brain barrier. It is also a route of entrance to the brain for several viruses and toxic substances. Airborne infectious, allergic and pollution agents are among the most common inflammatory factors which may affect brain function via the brain-nose interface. The inflammatory processes triggered in the upper respiratory tract by these agents are positioned to influence the immune response of the brain and therefore, influence its function and alter behavior. Several clinical and epidemiological studies find an association between inflammatory factors affecting the intranasal pathway and neurological disorders such as multiple sclerosis, Alzheimer and Parkinson diseases as well as mental disorders including anxiety and mood disorders. However the mechanisms of interaction between the immune response in the nasal epithelium and the brain are poorly understood. This article discusses current evidence about these mechanisms and associations with neurological and mental diseases.

  3. The Grueneberg ganglion: a novel sensory system in the nose.

    Science.gov (United States)

    Fleischer, Joerg; Breer, Heinz

    2010-07-01

    Within the nasal epithelium of mammals, there are several compartments which are populated with neuronal cells. One of them - the so-called Grueneberg ganglion - is composed of ciliated neurons residing in the anterior region of the nose. Although cells of the Grueneberg ganglion lack direct contact with the lumen of the nasal cavity, they are endowed with features indicative of olfactory sensory neurons, such as the olfactory marker protein and distinct olfactory receptors, as well as projection of axonal processes to the olfactory bulb of the brain. These findings have led to the notion that the Grueneberg ganglion might be a novel olfactory subsystem; a concept which was lately supported by the observation that chemical cues activate Grueneberg ganglion neurons. Unexpectedly, it was recently found that these cells also respond to cool ambient temperatures, presumably via a signaling pathway mediated by second messengers. Thus, the Grueneberg ganglion may operate as a dual sensory organ involved in the detection of both chemical and thermal stimuli.

  4. Separated flows near the nose of a body of revolution

    Science.gov (United States)

    Lin, S. P.

    1986-01-01

    The solution of the Navier-Stokes equations for the problem of cross-flow separataion about a deforming cylinder was achieved by iteration. It was shown that the separation starts at the rear stagnation point and the point of primary separation moves upstram along the cylinder surface. A general method of linear stability analysis for nonparallel external flows was constructed, which consists of representing the eigenfunctions with complete orthogonal sets and forms characteristic equations with the Galerkin method. The method was applied to the Kovasznay flow which is an exact solution of the Navier-Stokes equation. The results show that when the critical parameter is exceeded, there are only a few isolated unstable eigen-frequencies. Another exact solution is shown to be absolutely and monotonically stable with respect to infinitesimal disturbances of all frequencies. The flow is also globally, asymptotically, and monotonically stable in the mean with respect o three-dimensional disturbances. This result forms the sound foundation of rigorous stability analysis for nonparallel flows, and provides an invaluable test ground for future studies of nonparallel flows in which the basic states do not posses exact solutions. The application of this method to the study of the formation of spiral vorticies near the nose of a rotating body of revolution is underway. The same method will be applied to the stability analysis of reversed flow over a plate with suction.

  5. Glycerophospholipid Profiles of Bats with White Nose Syndrome

    Science.gov (United States)

    Pannkuk, Evan L.; Mcguire, Liam P.; Warnecke, Lisa; Turner, James M.; Willis, Craig K.R.; Risch, Thomas S.

    2015-01-01

    Pseudogymnoascus destructans is an ascomycetous fungus responsible for the disease dubbed white nose syndrome (WNS) and massive mortalities of cave dwelling bats. The fungus infects bat epidermal tissue causing damage to integumentary cells and pilosebaceous units. Differences in epidermal lipid composition caused by P. destructans infection could have drastic consequences for a variety of physiological functions, including innate immune efficiency and water retention. While bat surface lipid and stratum corneum lipid composition have been described; the differences in epidermal lipid content between healthy tissue and P. destructans infected tissue have not been documented. In this study, we analyzed the effect of wing damage from P. destructans infection on the epidermal polar lipid composition (glycerophospholipids [GPs] and sphingomyelin [SM]) of little brown bats (Myotis lucifugus). We hypothesized that bats infected with P. destructans would have altered lipid profiles compared to healthy bats. Polar lipids from three damaged and three healthy wing samples were profiled by electrospray ionization tandem mass spectrometry. The SM fraction was not significantly affected by P. destructans infection. We found lower total broad lipid levels in damaged tissue, specifically ether-linked phospholipids, lysophospholipids, phosphatidylcholine, and phosphatidylethanolamine. Thirteen individual GP species from 4 broad GP classes were present in higher amounts in healthy tissue. Six unsaturated GP species were absent in damaged tissue. Our results confirm P. destructans infection leads to altered lipid profiles. Clinical signs of WNS may include lower lipid levels and lower proportions of unsaturated lipids due to cellular and glandular damage. PMID:26052639

  6. Development of a Portable Electronic Nose System for the Detection and Classification of Fruity Odors

    Directory of Open Access Journals (Sweden)

    Kea-Tiong Tang

    2010-10-01

    Full Text Available In this study, we have developed a prototype of a portable electronic nose (E-Nose comprising a sensor array of eight commercially available sensors, a data acquisition interface PCB, and a microprocessor. Verification software was developed to verify system functions. Experimental results indicate that the proposed system prototype is able to identify the fragrance of three fruits, namely lemon, banana, and litchi.

  7. Effects of white-nose syndrome on regional population patterns of 3 hibernating bat species.

    Science.gov (United States)

    Ingersoll, Thomas E; Sewall, Brent J; Amelon, Sybill K

    2016-10-01

    Hibernating bats have undergone severe recent declines across the eastern United States, but the cause of these regional-scale declines has not been systematically evaluated. We assessed the influence of white-nose syndrome (an emerging bat disease caused by the fungus Pseudogymnoascus destructans, formerly Geomyces destructans) on large-scale, long-term population patterns in the little brown myotis (Myotis lucifugus), the northern myotis (Myotis septentrionalis), and the tricolored bat (Perimyotis subflavus). We modeled population trajectories for each species on the basis of an extensive data set of winter hibernacula counts of more than 1 million individual bats from a 4-state region over 13 years and with data on locations of hibernacula and first detections of white-nose syndrome at each hibernaculum. We used generalized additive mixed models to determine population change relative to expectations, that is, how population trajectories differed with a colony's infection status, how trajectories differed with distance from the point of introduction of white-nose syndrome, and whether declines were concordant with first local observation of the disease. Population trajectories in all species met at least one of the 3 expectations, but none met all 3. Our results suggest, therefore, that white-nose syndrome has affected regional populations differently than was previously understood and has not been the sole cause of declines. Specifically, our results suggest that in some areas and species, threats other than white-nose syndrome are also contributing to population declines, declines linked to white-nose syndrome have spread across large geographic areas with unexpected speed, and the disease or other threats led to declines in bat populations for years prior to disease detection. Effective conservation will require further research to mitigate impacts of white-nose syndrome, renewed attention to other threats to bats, and improved surveillance efforts to ensure

  8. In Tube Integrated Electronic Nose System on a Flexible Polymer Substrate

    Directory of Open Access Journals (Sweden)

    Gerhard Tröster

    2012-10-01

    Full Text Available The fabrication of electronic devices, such as gas sensors on flexible polymer substrates, enables the use of electronics in applications where conventional devices on stiff substrates could not be used. We demonstrate the development of a new intra-tube electronic-nose (e-nose gas sensor device with multiple sensors fabricated and integrated on a flexible substrate. For this purpose, we developed a new method of fabricating a sensor array of four gas sensors on a flexible polymer substrate. The method allowed the use of lithography techniques to pattern different polymers with a broad range of solubility parameters. Conductive polymer composites were used as a gas sensitive layer due to the high stretchability of the material. Each of the 30 e-nose devices on one substrate was designed to fit on a polymer strip with a width of 2 mm. A single e-nose strip was successfully integrated into the inlet tube of a gas-measurement apparatus with an inner-tube diameter of 3 mm. Using the e-nose, we were able to differentiate between four different volatile solvent vapors. The tube-integrated e-nose outperformed a chamber-integrated e-nose of the same type in terms of response time and flow-rate influences. The sensor array inside the tube showed a faster response time and detected short pulses of analyte exposure compared to the same sensor array outside of the tube. We measured gas flow rates from 1,000 to 30 sccm without significant changes in sensor performance using this intra-tube e-nose prototype. The tube could be bent to radii < 15 mm with a sensor performance similar to an unbent sensor.

  9. Prediction of Fatigue Life of Boom Nose End Casting Using Linear Elastic Fracture Mechanics

    OpenAIRE

    Nitin D.Ghongade; Rajesh.M. Metkar

    2014-01-01

    The main objective of this study is to get the life estimation of Boom nose end casting using theoretical approach and compaired it with finite element method. Therefore, this study consists of three major sections : (1) dynamic load analysis (2) FEM and stress analysis (3) prediction of fatigue life for Boom nose end casting. In this study a dynamic loads were obtained from cyclic loading at different time. Finite element analysis was performed to obtain the variation of stress...

  10. In tube integrated electronic nose system on a flexible polymer substrate.

    Science.gov (United States)

    Kinkeldei, Thomas; Zysset, Christoph; Münzenrieder, Niko; Petti, Luisa; Tröster, Gerhard

    2012-10-12

    The fabrication of electronic devices, such as gas sensors on flexible polymer substrates, enables the use of electronics in applications where conventional devices on stiff substrates could not be used. We demonstrate the development of a new intra-tube electronic-nose (e-nose) gas sensor device with multiple sensors fabricated and integrated on a flexible substrate. For this purpose, we developed a new method of fabricating a sensor array of four gas sensors on a flexible polymer substrate. The method allowed the use of lithography techniques to pattern different polymers with a broad range of solubility parameters. Conductive polymer composites were used as a gas sensitive layer due to the high stretchability of the material. Each of the 30 e-nose devices on one substrate was designed to fit on a polymer strip with a width of 2 mm. A single e-nose strip was successfully integrated into the inlet tube of a gas-measurement apparatus with an inner-tube diameter of 3 mm. Using the e-nose, we were able to differentiate between four different volatile solvent vapors. The tube-integrated e-nose outperformed a chamber-integrated e-nose of the same type in terms of response time and flow-rate influences. The sensor array inside the tube showed a faster response time and detected short pulses of analyte exposure compared to the same sensor array outside of the tube. We measured gas flow rates from 1,000 to 30 sccm without significant changes in sensor performance using this intra-tube e-nose prototype. The tube could be bent to radii sensor performance similar to an unbent sensor.

  11. How does nose blowing effect the computed tomography of paranasal sinuses in chronic sinusitis?

    Energy Technology Data Exchange (ETDEWEB)

    Savranlar, Ahmet; Uzun, Lokman; Ugur, Mehmet Birol; Mahmutyazicioglu, Kamran; Ozer, Tulay; Gundogdu, Sadi

    2005-02-01

    Objective: Our aim was to determine whether inward or outward movement of the secretions in the paranasal sinuses due to nose blowing after nasal decongestion has any effect on the paranasal sinus computed tomography (CT) images in patients with sinusitis and to asses whether nose blowing may result in misdiagnosis or overdiagnosis in radiological evaluation of sinusitis. Materials and methods: Twenty-four patients with chronic sinusitis were evaluated in an academic tertiary care hospital and data were collected prospectively. After coronal sinus computed tomography scans were performed at 100 mA setting which was half the value of the standard radiation dose suggested by the manufacturer, topical decongestion was applied to each nostril followed by nose blowing 10 min later. Sinus CT scans were then repeated at the same setting. We evaluated the mucosal thickness of medial, lateral, superior and inferior maxillary and frontal sinus walls and the maximal thickness in anterior ethmoidal cells. The measurements prior to and following nose blowing were compared with Wilcoxon signed ranks test. The obtained images were also staged using Lund-McKay staging system separately and the scores were compared with Student's t-test. Results: We observed a tendency towards reduction in mucosal thickness after nose blowing. There were statistically significant differences between maxillary sinus inferior wall and frontal sinus inferior wall mucosal thickness values prior to and after nose blowing. The difference however was very small, about 0.5 mm in magnitude and Lund-McKay score did not change in any of the patients after nose blowing. Conclusion: Nose blowing and topical nasal decongestion does not have any effect on the diagnostic accuracy of sinus CT in chronic sinusitis patients.

  12. Design of a portable electronic nose for real-fake detection of liquors

    Science.gov (United States)

    Qi, Pei-Feng; Zeng, Ming; Li, Zhi-Hua; Sun, Biao; Meng, Qing-Hao

    2017-09-01

    Portability is a major issue that influences the practical application of electronic noses (e-noses). For liquors detection, an e-nose must preprocess the liquid samples (e.g., using evaporation and thermal desorption), which makes the portable design even more difficult. To realize convenient and rapid detection of liquors, we designed a portable e-nose platform that consists of hardware and software systems. The hardware system contains an evaporation/sampling module, a reaction module, a control/data acquisition and analysis module, and a power module. The software system provides a user-friendly interface and can achieve automatic sampling and data processing. This e-nose platform has been applied to the real-fake recognition of Chinese liquors. Through parameter optimization of a one-class support vector machine classifier, the error rate of the negative samples is greatly reduced, and the overall recognition accuracy is improved. The results validated the feasibility of the designed portable e-nose platform.

  13. Discrimination of chicken seasonings and beef seasonings using electronic nose and sensory evaluation.

    Science.gov (United States)

    Tian, Huaixiang; Li, Fenghua; Qin, Lan; Yu, Haiyan; Ma, Xia

    2014-11-01

    This study examines the feasibility of electronic nose as a method to discriminate chicken and beef seasonings and to predict sensory attributes. Sensory evaluation showed that 8 chicken seasonings and 4 beef seasonings could be well discriminated and classified based on 8 sensory attributes. The sensory attributes including chicken/beef, gamey, garlic, spicy, onion, soy sauce, retention, and overall aroma intensity were generated by a trained evaluation panel. Principal component analysis (PCA), discriminant factor analysis (DFA), and cluster analysis (CA) combined with electronic nose were used to discriminate seasoning samples based on the difference of the sensor response signals of chicken and beef seasonings. The correlation between sensory attributes and electronic nose sensors signal was established using partial least squares regression (PLSR) method. The results showed that the seasoning samples were all correctly classified by the electronic nose combined with PCA, DFA, and CA. The electronic nose gave good prediction results for all the sensory attributes with correlation coefficient (r) higher than 0.8. The work indicated that electronic nose is an effective method for discriminating different seasonings and predicting sensory attributes.

  14. Threshold detection of aromatic compounds in wine with an electronic nose and a human sensory panel.

    Science.gov (United States)

    Santos, José Pedro; Lozano, Jesús; Aleixandre, Manuel; Arroyo, Teresa; Cabellos, Juan Mariano; Gil, Mar; Horrillo, Maria del Carmen

    2010-03-15

    An electronic nose (e-nose) based on thin film semiconductor sensors has been developed in order to compare the performance in threshold detection and concentration quantification with a trained human sensory panel in order to demonstrate the use of an e-nose to assess the enologists in an early detection of some chemical compounds in order to prevent wine defects. The panel had 25 members and was trained to detect concentration thresholds of some compounds of interest present in wine. Typical red wine compounds such as whiskeylactone and white wine compounds such as 3-methyl butanol were measured at different concentrations starting from the detection threshold found in literature (in the nanograms to milligrams per liter range). Pattern recognition methods (principal component analysis (PCA) and neural networks) were used to process the data. The results showed that the performance of the e-nose for threshold detection was much better than the human panel. The compounds were detected by the e-nose at concentrations up to 10 times lower than the panel. Moreover the e-nose was able to identify correctly each concentration level therefore quantitative applications are devised for this system. Copyright (c) 2009 Elsevier B.V. All rights reserved.

  15. Detection and Classification of Human Body Odor Using an Electronic Nose

    Directory of Open Access Journals (Sweden)

    Teerakiat Kerdcharoen

    2009-09-01

    Full Text Available An electronic nose (E-nose has been designed and equipped with software that can detect and classify human armpit body odor. An array of metal oxide sensors was used for detecting volatile organic compounds. The measurement circuit employs a voltage divider resistor to measure the sensitivity of each sensor. This E-nose was controlled by in-house developed software through a portable USB data acquisition card with a principle component analysis (PCA algorithm implemented for pattern recognition and classification. Because gas sensor sensitivity in the detection of armpit odor samples is affected by humidity, we propose a new method and algorithms combining hardware/software for the correction of the humidity noise. After the humidity correction, the E-nose showed the capability of detecting human body odor and distinguishing the body odors from two persons in a relative manner. The E-nose is still able to recognize people, even after application of deodorant. In conclusion, this is the first report of the application of an E-nose for armpit odor recognition.

  16. Dynamical and thermal qualification of the C-SiC nose for the IXV

    Science.gov (United States)

    Buffenoir, François; Escafre, David; Brault, Tiana; Rival, Loic; Girard, Florent

    2016-07-01

    The Intermediate experimental Vehicle (IXV) atmospheric re-entry demonstrator, developed within the FLPP (Future Launcher Preparatory Program) and funded by ESA, was aimed at developing a demonstration vehicle that gave Europe a unique opportunity to increase its knowledge in the field of advanced atmospheric re-entry technologies. Within this program, HERAKLES, Safran Group, was in charge of the TPS of the windward and nose assemblies of the vehicle, and has developed and manufactured SepcarbInox® Ceramic Matrix Composite (CMC) protection systems that provided a high temperature resistant nonablative outer mold line (OML) for enhanced aerodynamic control. A key component of this TPS is the nose assembly, which is one the most loaded part during re-entry. The paper describes the analysis activities that led to the qualification of the nose assembly, through two activities: Dynamical behavior of the nose. Thermal behavior of the nose For both cases, the paper shows how FE models, compared with tests results, led to the understanding and simulation of the nose assembly behavior, allowing HERAKLES to confirm the design margins before flight.

  17. The Multi-Chamber Electronic Nose--an improved olfaction sensor for mobile robotics.

    Science.gov (United States)

    Gonzalez-Jimenez, Javier; Monroy, Javier G; Blanco, Jose Luis

    2011-01-01

    One of the major disadvantages of the use of Metal Oxide Semiconductor (MOS) technology as a transducer for electronic gas sensing devices (e-noses) is the long recovery period needed after each gas exposure. This severely restricts its usage in applications where the gas concentrations may change rapidly, as in mobile robotic olfaction, where allowing for sensor recovery forces the robot to move at a very low speed, almost incompatible with any practical robot operation. This paper describes the design of a new e-nose which overcomes, to a great extent, such a limitation. The proposed e-nose, called Multi-Chamber Electronic Nose (MCE-nose), comprises several identical sets of MOS sensors accommodated in separate chambers (four in our current prototype), which alternate between sensing and recovery states, providing, as a whole, a device capable of sensing changes in chemical concentrations faster. The utility and performance of the MCE-nose in mobile robotic olfaction is shown through several experiments involving rapid sensing of gas concentration and mobile robot gas mapping.

  18. Coupling gas chromatography and electronic nose detection for detailed cigarette smoke aroma characterization.

    Science.gov (United States)

    Rambla-Alegre, Maria; Tienpont, Bart; Mitsui, Kazuhisa; Masugi, Eri; Yoshimura, Yuta; Nagata, Hisanori; David, Frank; Sandra, Pat

    2014-10-24

    Aroma characterization of whole cigarette smoke samples using sensory panels or electronic nose (E-nose) devices is difficult due to the masking effect of major constituents and solvent used for the extraction step. On the other hand, GC in combination with olfactometry detection does not allow to study the delicate balance and synergetic effect of aroma solutes. To overcome these limitations a new instrumental set-up consisting of heart-cutting gas chromatography using a capillary flow technology based Deans switch and low thermal mass GC in combination with an electronic nose device is presented as an alternative to GC-olfactometry. This new hyphenated GC-E-nose configuration is used for the characterization of cigarette smoke aroma. The system allows the transfer, combination or omission of selected GC fractions before injection in the E-nose. Principal component analysis (PCA) and discriminant factor analysis (DFA) allowed clear visualizing of the differences among cigarette brands and classifying them independently of their nicotine content. Omission and perceptual interaction tests could also be carried out using this configuration. The results are promising and suggest that the GC-E-nose hyphenation is a good approach to measure the contribution level of individual compounds to the whole cigarette smoke. Copyright © 2014 Elsevier B.V. All rights reserved.

  19. The olfactory fascia: an evo-devo concept of the fibrocartilaginous nose.

    Science.gov (United States)

    Jankowski, Roger; Rumeau, Cécile; de Saint Hilaire, Théophile; Tonnelet, Romain; Nguyen, Duc Trung; Gallet, Patrice; Perez, Manuela

    2016-12-01

    Evo-devo is the science that studies the link between evolution of species and embryological development. This concept helps to understand the complex anatomy of the human nose. The evo-devo theory suggests the persistence in the adult of an anatomical entity, the olfactory fascia, that unites the cartilages of the nose to the olfactory mucosa. We dissected two fresh specimens. After resecting the superficial tissues of the nose, dissection was focused on the disarticulation of the fibrocartilaginous noses from the facial and skull base skeleton. Dissection shows two fibrocartilaginous sacs that were invaginated side-by-side in the midface and attached to the anterior skull base. These membranous sacs were separated in the midline by the perpendicular plate of the ethmoid. Their walls contained the alar cartilages and the lateral expansions of the septolateral cartilage, which we had to separate from the septal cartilage. The olfactory mucosa was located inside their cranial ends. The olfactory fascia is a continuous membrane uniting the nasal cartilages to the olfactory mucosa. Its origin can be found in the invagination and differentiation processes of the olfactory placodes. The fibrous portions of the olfactory fascia may be described as ligaments that unit the different components of the olfactory fascia one to the other and the fibrocartilaginous nose to the facial and skull base skeleton. The basicranial ligaments, fixing the fibrocartilaginous nose to the skull base, represent key elements in the concept of septorhinoplasty by disarticulation.

  20. Iterative smoothing and deconvolution of one- and two-dimensional elemental distribution data

    Science.gov (United States)

    Coote, G. E.

    1997-07-01

    The resolution of the data from many instruments can be improved, or the rate of data collection can be increased for the same final resolution, by applying to the data reliable algorithms for smoothing and deconvolution. Iterative methods which were formerly impractical can easily be applied on a small computer. An ingenious linear algorithm for deconvolution of one-dimensional data (van Cittert, 1931) gave much better results when Jansson (1963) introduced a relaxation function which ensured the results remained positive. Gold (1964) derived by a matrix approach a nonlinear algorithm which used a different method of comparison, but Xu et al. showed 30 years later that it is a special van Cittert algorithm with a variable relaxation function. Tests of Gold's method show that it is reliable and much faster than Jansson's algorithm, converging in 20 iterations or fewer. If a microprobe beam spot is to a good approximation square or rectangular a 2-D image can be smoothed or deconvolved in the X and Y directions independently, and the Gold algorithm has proved suitable for the deconvolution stage. Almost all smoothing methods will broaden narrow peaks, but an exception is the linear iterative method of Morrison (1962), which reduces any structure narrower than the resolution function. The negative feedback step used in the deconvolution algorithms is not possible in a smoothing algorithm. The method suffers from a halting problem, since it smoothes during early iterations but eventually reproduces the original data. This can be prevented by introducing a relaxation function which is unity for the first iteration but decreases rapidly with succeeding iterations.

  1. Approximation of Bivariate Functions via Smooth Extensions

    Science.gov (United States)

    Zhang, Zhihua

    2014-01-01

    For a smooth bivariate function defined on a general domain with arbitrary shape, it is difficult to do Fourier approximation or wavelet approximation. In order to solve these problems, in this paper, we give an extension of the bivariate function on a general domain with arbitrary shape to a smooth, periodic function in the whole space or to a smooth, compactly supported function in the whole space. These smooth extensions have simple and clear representations which are determined by this bivariate function and some polynomials. After that, we expand the smooth, periodic function into a Fourier series or a periodic wavelet series or we expand the smooth, compactly supported function into a wavelet series. Since our extensions are smooth, the obtained Fourier coefficients or wavelet coefficients decay very fast. Since our extension tools are polynomials, the moment theorem shows that a lot of wavelet coefficients vanish. From this, with the help of well-known approximation theorems, using our extension methods, the Fourier approximation and the wavelet approximation of the bivariate function on the general domain with small error are obtained. PMID:24683316

  2. Dual-support Smoothed Particle Hydrodynamics

    CERN Document Server

    Ren, Huilong; Zhuang, Xiaoying; Rabczuk, Timon

    2016-01-01

    In this paper we develop a dual-support smoothed particle hydrodynamics (DS-SPH) that naturally satisfies the conservation of momentum, angular momentum and energy when the varying smoothing length is utilized. The DS-SPH is based on the concept of dual-support, which is introduced to consider the unbalanced interactions between the particles with different smoothing lengths. Our DS-SPH formulation can be implemented in traditional SPH with little changes and improve the computational efficiency. Several numerical examples are presented to demonstrate the capability of the method.

  3. Nonequilibrium Flows with Smooth Particle Applied Mechanics.

    Science.gov (United States)

    Kum, Oyeon

    Smooth particle methods are relatively new methods for simulating solid and fluid flows though they have a 20-year history of solving complex hydrodynamic problems in astrophysics, such as colliding planets and stars, for which correct answers are unknown. The results presented in this thesis evaluate the adaptability or fitness of the method for typical hydrocode production problems. For finite hydrodynamic systems, boundary conditions are important. A reflective boundary condition with image particles is a good way to prevent a density anomaly at the boundary and to keep the fluxes continuous there. Boundary values of temperature and velocity can be separately controlled. The gradient algorithm, based on differentiating the smooth particle expressions for (urho) and (Trho), does not show numerical instabilities for the stress tensor and heat flux vector quantities which require second derivatives in space when Fourier's heat -flow law and Newton's viscous force law are used. Smooth particle methods show an interesting parallel linking them to molecular dynamics. For the inviscid Euler equation, with an isentropic ideal gas equation of state, the smooth particle algorithm generates trajectories isomorphic to those generated by molecular dynamics. The shear moduli were evaluated based on molecular dynamics calculations for the three weighting functions, B spline, Lucy, and Cusp functions. The accuracy and applicability of the methods were estimated by comparing a set of smooth particle Rayleigh -Benard problems, all in the laminar regime, to corresponding highly-accurate grid-based numerical solutions of continuum equations. Both transient and stationary smooth particle solutions reproduce the grid-based data with velocity errors on the order of 5%. The smooth particle method still provides robust solutions at high Rayleigh number where grid-based methods fails. Considerably fewer smooth particles are required than atoms in a corresponding molecular dynamics

  4. Diging simulation of a narrow trench

    Science.gov (United States)

    Anghelache, D. G.; Goanta, A. M.

    2016-08-01

    In this paper, we realized digging process simulation for a narrow trench using special equipment located at a mini excavator. These types of machines digging perform the longitudinal direction to the direction of travel, making trenches with widths of 0.4 m and depths of 3.5 -7.0 m. These are necessary for the location of underground cables or draining water in agriculture. For Parametric modelling of parts included in ensemble has used software from Siemens NX 7.5, we produce sketches of each piece, using following commands: Sketch, Profile (Line), Arc, Circle, Quick Trim Quick Extend, Constraints. Depending on the layout of each piece can also use other commands such as: Chamfer, Rotate, Mirror Curve, Offset Curve, etc. After completion of sketch and dimensioning commands was: Extrude, Revolve, and at this stage the play may various modifications such as drilling, removal of certain volumes of piece showing various forms or change the appearance of surfaces (thread cutting, bevelling). This paper was realized with this parametric modelling software because presents major advantages including: control over the design, making design speed and increasing productivity; increasing product quality, reducing design risk recovery and time work, less human effort and reduced financial resources throughout the process.

  5. Narrow and broad senses on salinity scale

    Institute of Scientific and Technical Information of China (English)

    2001-01-01

    The narrow sense and applicable limit of Practical Salinity Scale 1978 (PSS78) and volumetric titration using silver nitrate to measure the salinity of non-conservative oceanwater are discussed.The salinity obtained by electrical conductivity method and chlorinity salinity method obviously deviates from the absolute salinity (SA). The Density Salinity Scale (DSS98) proposed by the writers can be extensively used in conservative and non-conservative water samples.The merits of the density salinity scale are as follows,(1) The Density Salinity Scale is only related to seawater mass and its buoyant effect, and is not influenced by the variation in seawater composition, and therefore, has high reliability, and repeatability for salinity determination.(2) The salinity values measured by the DSS98 have a conservative property. For oceanwater samples the salinity values are the same as those determined by the PSS78; for non-conservative water samples (e.g. samples from industrial sources), the salinity values are close to the absolute salinity values in comparison with those measured by the PSS78 and the Knudsen method.(3)For a solution with given solute mass, the solution concentration can be converted into the corresponding salinity by the Density Salinity Scale using the expansion coefficient of the solution and the calibration coefficient of the partial molar volume of the solute.

  6. A Brief History of Airway Smooth Muscle’s Role in Airway Hyperresponsiveness

    Directory of Open Access Journals (Sweden)

    C. D. Pascoe

    2012-01-01

    Full Text Available A link between airway smooth muscle (ASM and airway hyperresponsiveness (AHR in asthma was first postulated in the midnineteenth century, and the suspected link has garnered ever increasing interest over the years. AHR is characterized by excessive narrowing of airways in response to nonspecific stimuli, and it is the ASM that drives this narrowing. The stimuli that can be used to demonstrate AHR vary widely, as do the potential mechanisms by which phenotypic changes in ASM or nonmuscle factors can contribute to AHR. In this paper, we review the history of research on airway smooth muscle’s role in airway hyperresponsiveness. This research has ranged from analyzing the quantity of ASM in the airways to testing for alterations in the plastic behavior of smooth muscle, which distinguishes it from skeletal and cardiac muscles. This long history of research and the continued interest in this topic mean that the precise role of ASM in airway responsiveness remains elusive, which makes it a pertinent topic for this collection of articles.

  7. Ogive Nose Hard Missile Penetrating Concrete Slab Numerical Simulation Approach

    Directory of Open Access Journals (Sweden)

    Qadir Bux

    2011-01-01

    Full Text Available Great demand exists for more efficient design to protect delicate and serious structures such as nuclear plants, Power plants, Weapon Industries, weapons storage places, water retaining structures, & etc, against impact of kinetic missiles generated both accidentally and deliberately such as dynamic loading, incident occurs in nuclear plants, terrorist attack, Natural disasters like tsunami and etc., in various impact and blast scenarios for both civilian and military activities. In many cases, projectiles can be treated as rigid bodies when their damage and erosion are not severe. Due to the intricacy of the local impact damages, investigations are generally based on experimental data. Conclusions of the experimental observations are then used to guide engineering models. Local damages studies normally fall into three categories, i.e. empirical formulae based on data fitting, idealised analytical models based on physic laws and numerical simulations based on computational mechanics and material models. In the present study, 2D asymmetrical numerical simulation have done on concrete slab against the impact of  ogive nose hard missile of 26.90mm and 76.20mm diameter with CRH ratio 2.0 and 6.0 respectively, for penetration by using Concrete Damaged Plasticity Model, and ABAQUS/Explicit dynamic analysis in ABAQUS. It is found that the strains/stresses are induced in the concrete slab and a very nicely propagation of the stresses inside the  concrete slab in the form of waves, which is a clear indication for vibrations of the concrete. The lack of failure criterion in concrete damaged plasticity model does not allow the removal of elements during the analyses. This means that spalling, scabbing, and perforation cannot be modelled with the Concrete Damage Plasticity Model. The penetration depth results shows that the deeper penetration requires higher critical impact kinetic energies, and comparison shows the simulation results are more accurate

  8. Aerodynamics of a Gulfstream G550 Nose Landing Gear Model

    Science.gov (United States)

    Neuhart, Dan H.; Khorrami, Mehdi R.; Choudhari, Meelan M.

    2009-01-01

    In this paper we discuss detailed steady and unsteady aerodynamic measurements of a Gulfstream G550 nose landing gear model. The quarter-scale, high-fidelity model includes part of the lower fuselage and the gear cavity. The full model configuration allowed for removal of various gear components (e.g. light cluster, steering mechanism, hydraulic lines, etc.) in order to document their effects on the local flow field. The measurements were conducted at a Reynolds number of 7.3 x 10(exp 4) based on the shock strut (piston) diameter and a freestream Mach number of 0.166. Additional data were also collected at lower Mach numbers of 0.12 and 0.145 and correspondingly lower Reynolds numbers. The boundary layer on the piston was tripped to enable turbulent flow separation, so as to better mimic the conditions encountered during flight. Steady surface pressures were gathered from an extensive number of static ports on the wheels, door, fuselage, and within the gear cavity. To better understand the resultant flow interactions between gear components, surface pressure fluctuations were collected via sixteen dynamic pressure sensors strategically placed on various subcomponents of the gear. Fifteen of the transducers were flush mounted on the gear surface at fixed locations, while the remaining one was a mobile transducer that could be placed at numerous varying locations. The measured surface pressure spectra are mainly broadband in nature, lacking any local peaks associated with coherent vortex shedding. This finding is in agreement with off-surface flow measurements using PIV that revealed the flow field to be a collection of separated shear layers without any dominant vortex shedding processes.

  9. White-nose syndrome in bats: illuminating the darkness

    Science.gov (United States)

    Cryan, Paul M.; Meteyer, Carol U.; Boyles, Justin G.; Blehert, David S.

    2013-01-01

    Happy ten-year anniversary to BMC Biology! We can attest to the effectiveness of the journal in reaching a great diversity of scientists based on reader responses to our commentary [1] about bat white-nose syndrome (WNS) two years ago. WNS is still on course to rank among the most destructive wildlife diseases to emerge in recent history, and it has continued to have unprecedented effects on populations of hibernating bats in eastern North America. At the time of our last writing in November 2010, the cold-adapted fungus then presumed to cause WNS (Geomyces destructans) had spread about 1,300 km from an index site in New York (Figure 1). In those early years of the epizootic, WNS caused a staggering wave of mass mortality among all six species of hibernating bats that occur in north-eastern North America. Since November 2010, WNS has spread into eight additional US states and two more Canadian provinces (Figure 1), and has continued to cause mortality in those six species most affected during the early years of the epizootic. Although part of a mostly tragic story has continued to unfold as new areas are affected, anecdotal signs are emerging that all may not be lost when it comes to hibernating bats and WNS. Amid the continued large-scale population declines of certain species, we have yet to see mass mortality in some of the more westerly areas where the fungus was detected two winters ago (Figure 1). Also, recently disease without obvious mortality was diagnosed in gray bats (Myotis grisescens) - an endangered species thought by many two years ago to be at high risk of extinction from WNS. Clearly, large gaps in our understanding of WNS remain, but some have been filled since we last communicated with readers of BMC Biology.

  10. Smooth surfaces from rational bilinear patches

    KAUST Repository

    Shi, Ling

    2014-01-01

    Smooth freeform skins from simple panels constitute a challenging topic arising in contemporary architecture. We contribute to this problem area by showing how to approximate a negatively curved surface by smoothly joined rational bilinear patches. The approximation problem is solved with help of a new computational approach to the hyperbolic nets of Huhnen-Venedey and Rörig and optimization algorithms based on it. We also discuss its limits which lie in the topology of the input surface. Finally, freeform deformations based on Darboux transformations are used to generate smooth surfaces from smoothly joined Darboux cyclide patches; in this way we eliminate the restriction to surfaces with negative Gaussian curvature. © 2013 Elsevier B.V.

  11. Fractional Smoothness of Some Stochastic Integrals

    Institute of Scientific and Technical Information of China (English)

    Peng XIE; Xi Cheng ZHANG

    2007-01-01

    We study the fractional smoothness in the sense of Malliavin calculus of stochastic integralsof the form ∫10 φ(Xs)d Xs,where Xs is a semimartingale and φ belongs to some fractional Sobolev spaceover R.

  12. Spectral sequences in smooth generalized cohomology

    CERN Document Server

    Grady, Daniel

    2016-01-01

    We consider spectral sequences in smooth generalized cohomology theories, including differential generalized cohomology theories. The main differential spectral sequences will be of the Atiyah-Hirzebruch (AHSS) type, where we provide a filtration by the Cech resolution of smooth manifolds. This allows for systematic study of torsion in differential cohomology. We apply this in detail to smooth Deligne cohomology, differential topological complex K-theory, and to a smooth extension of integral Morava K-theory that we introduce. In each case we explicitly identify the differentials in the corresponding spectral sequences, which exhibit an interesting and systematic interplay between (refinement of) classical cohomology operations, operations involving differential forms, and operations on cohomology with U(1) coefficients.

  13. Integrated Groups and Smooth Distribution Groups

    Institute of Scientific and Technical Information of China (English)

    Pedro J. MIANA

    2007-01-01

    In this paper, we prove directly that α-times integrated groups define algebra homo-morphisms. We also give a theorem of equivalence between smooth distribution groups and α-times integrated groups.

  14. Cardiac, Skeletal, and smooth muscle mitochondrial respiration

    DEFF Research Database (Denmark)

    Park, Song-Young; Gifford, Jayson R; Andtbacka, Robert H I

    2014-01-01

    Unlike cardiac and skeletal muscle, little is known about vascular smooth muscle mitochondrial function. Therefore, this study examined mitochondrial respiratory rates in the smooth muscle of healthy human feed arteries and compared with that of healthy cardiac and skeletal muscle. Cardiac......, skeletal, and smooth muscle was harvested from a total of 22 subjects (53±6 yrs) and mitochondrial respiration assessed in permeabilized fibers. Complex I+II, state 3 respiration, an index of oxidative phosphorylation capacity, fell progressively from cardiac, skeletal, to smooth muscle (54±1; 39±4; 15......±1 pmol•s(-1)•mg (-1), psmooth muscle (222±13; 115±2; 48±2 umol•g(-1)•min(-1), p

  15. Valiente Kroon's obstructions to smoothness at infinity

    Science.gov (United States)

    Grant, James; Tod, Paul

    2015-03-01

    We conjecture an interpretation in terms of multipole moments of the obstructions to smoothness at infinity found for time-symmetric, conformally-flat initial data by Kroon (Commun Math Phys 244(1):133-156, 2004).

  16. Narrowing of the ITCZ in a warming climate: Physical mechanisms

    Science.gov (United States)

    Byrne, Michael P.; Schneider, Tapio

    2016-11-01

    The Intertropical Convergence Zone (ITCZ) narrows in response to global warming in both observations and climate models. However, a physical understanding of this narrowing is lacking. Here we show that the narrowing of the ITCZ in simulations of future climate is related to changes in the moist static energy (MSE) budget. MSE advection by the mean circulation and MSE divergence by transient eddies tend to narrow the ITCZ, while changes in net energy input to the atmosphere and the gross moist stability tend to widen the ITCZ. The narrowing tendency arises because the meridional MSE gradient strengthens with warming, whereas the largest widening tendency is due to increasing shortwave heating of the atmosphere. The magnitude of the ITCZ narrowing depends strongly on the gross moist stability and clouds, emphasizing the need to better understand these fundamental processes in the tropical atmosphere.

  17. An Owner's Guide to Smoothed Particle Hydrodynamics

    OpenAIRE

    Martin, T.J.; Pearce, F. R.; Thomas, P. A.

    1993-01-01

    We present a practical guide to Smoothed Particle Hydrodynamics (\\SPH) and its application to astrophysical problems. Although remarkably robust, \\SPH\\ must be used with care if the results are to be meaningful since the accuracy of \\SPH\\ is sensitive to the arrangement of the particles and the form of the smoothing kernel. In particular, the initial conditions for any \\SPH\\ simulation must consist of particles in dynamic equilibrium. We describe some of the numerical difficulties that may be...

  18. Rubber friction on (apparently) smooth lubricated surfaces

    Energy Technology Data Exchange (ETDEWEB)

    Mofidi, M; Prakash, B [Division of Machine Elements, Luleaa University of Technology, Luleaa SE-97187 (Sweden); Persson, B N J [IFF, FZ-Juelich, 52425 Juelich (Germany); Albohr, O [Pirelli Deutschland AG, 64733 Hoechst/Odenwald, Postfach 1120 (Germany)

    2008-02-27

    We study rubber sliding friction on hard lubricated surfaces. We show that even if the hard surface appears smooth to the naked eye, it may exhibit short-wavelength roughness, which may make the dominant contribution to rubber friction. That is, the observed sliding friction is mainly due to the viscoelastic deformations of the rubber by the counterface surface asperities. The results presented are of great importance for rubber sealing and other rubber applications involving (apparently) smooth surfaces.

  19. Robust chaos in smooth unimodal maps

    Science.gov (United States)

    Andrecut, M.; Ali, M. K.

    2001-08-01

    Robust chaos is defined by the absence of periodic windows and coexisting attractors in some neighborhood of the parameter space. It has been conjectured that robust chaos cannot occur in smooth systems [E. Barreto, B. Hunt, and C. Grebogi, Phys. Rev. Lett. 78, 4561 (1997); 80, 3049 (1998)]. Contrary to this conjecture, we describe a general procedure for generating robust chaos in smooth unimodal maps.

  20. Observability and Controllability for Smooth Nonlinear Systems

    OpenAIRE

    Schaft, A.J. van der

    1982-01-01

    The definition of a smooth nonlinear system as proposed recently, is elaborated as a natural generalization of the more common definitions of a smooth nonlinear input-output system. Minimality for such systems can be defined in a very direct geometric way, and already implies a usual notion of observability, namely, local weak observability. As an application of this theory, it is shown that observable nonlinear Hamiltonian systems are necessarily controllable, and vice versa.

  1. Rubber friction on (apparently) smooth lubricated surfaces

    Science.gov (United States)

    Mofidi, M.; Prakash, B.; Persson, B. N. J.; Albohr, O.

    2008-02-01

    We study rubber sliding friction on hard lubricated surfaces. We show that even if the hard surface appears smooth to the naked eye, it may exhibit short-wavelength roughness, which may make the dominant contribution to rubber friction. That is, the observed sliding friction is mainly due to the viscoelastic deformations of the rubber by the counterface surface asperities. The results presented are of great importance for rubber sealing and other rubber applications involving (apparently) smooth surfaces.

  2. Doing smooth pursuit paradigms in Windows 7

    DEFF Research Database (Denmark)

    Wilms, Inge Linda

    Smooth pursuit eye movements are interesting to study as they reflect the subject’s ability to predict movement of external targets, keep focus and move the eyes appropriately. The process of smooth pursuit requires collaboration between several systems in the brain and the resulting action may p...... in Windows 7 with live capturing of eye movements using a Tobii TX300 eye tracker. In particular, the poster describes the challenges and limitations created by the hardware and the software...

  3. Efficient Smoothing for Boundary Value Models

    Science.gov (United States)

    1989-12-29

    IEEE Transactions on Automatic Control , vol. 29, pp. 803-821, 1984. [2] A. Bagchi and H. Westdijk, "Smoothing...and likelihood ratio for Gaussian boundary value processes," IEEE Transactions on Automatic Control , vol. 34, pp. 954-962, 1989. [3] R. Nikoukhah et...77-96, 1988. [6] H. L. Weinert and U. B. Desai, "On complementary models and fixed- interval smoothing," IEEE Transactions on Automatic Control ,

  4. Laser frequency bandwidth narrowing by photorefractive two-beam coupling.

    Science.gov (United States)

    Chomsky, D; Sternklar, S; Zigler, A; Jackel, S

    1992-04-01

    We present a theoretical analysis and experimental demonstration of a new method for spectral narrowing of laser radiation. The bandwidth narrowing is experienced by a laser beam subjected to a photorefractive two-beam coupling process. Contrary to the conventional method of frequency filtering by a Fabry-Perot étalon, this technique has no intrinsic finesse limitation on its resolution. A factor of 2 in frequency bandwidth narrowing is achieved with an argon-ion laser.

  5. Beam-smoothing investigation on Heaven I

    Science.gov (United States)

    Xiang, Yi-huai; Gao, Zhi-xing; Tong, Xiao-hui; Dai, Hui; Tang, Xiu-zhang; Shan, Yu-sheng

    2007-01-01

    Directly driven targets for inertial confinement fusion (ICF) require laser beams with extremely smooth irradiance profiles to prevent hydrodynamic instabilities that destroy the spherical symmetry of the target during implosion. Such instabilities can break up and mix together the target's wall and fuel material, preventing it from reaching the density and temperature required for fusion ignition. 1,2 Measurements in the equation of state (EOS) experiments require laser beams with flat-roofed profiles to generate uniform shockwave 3. Some method for beam smooth, is thus needed. A technique called echelon-free induced spatial incoherence (EFISI) is proposed for producing smooth target beam profiles with large KrF lasers. The idea is basically an image projection technique that projects the desired time-averaged spatial profile onto the target via the laser system, using partially coherent broadband lighe. Utilize the technique, we developing beam- smoothing investigation on "Heaven I". At China Institute of Atomic Energy , a new angular multiplexing providing with beam-smoothing function has been developed, the total energy is 158J, the stability of energy is 4%, the pulse duration is 25ns, the effective diameter of focusing spot is 400um, and the ununiformity is about 1.6%, the power density on the target is about 3.7×10 12W/cm2. At present, the system have provided steady and smooth laser irradiation for EOS experiments.

  6. Bacteria isolated from bats inhibit the growth of Pseudogymnoascus destructans, the causative agent of white-nose syndrome

    National Research Council Canada - National Science Library

    Hoyt, Joseph R; Cheng, Tina L; Langwig, Kate E; Hee, Mallory M; Frick, Winifred F; Kilpatrick, A Marm

    2015-01-01

    .... White-nose syndrome, caused by the fungal skin pathogen Pseudogymnoascus destructans, threatens several hibernating bat species with extinction and there are few effective treatment strategies...

  7. Bronchoprotective effect of simulated deep inspirations in tracheal smooth muscle.

    Science.gov (United States)

    Pascoe, Christopher D; Donovan, Graham M; Bossé, Ynuk; Seow, Chun Y; Paré, Peter D

    2014-12-15

    Deep inspirations (DIs) taken before an inhaled challenge with a spasmogen limit airway responsiveness in nonasthmatic subjects. This phenomenon is called bronchoprotection and is severely impaired in asthmatic subjects. The ability of DIs to prevent a decrease in forced expiratory volume in 1 s (FEV1) was initially attributed to inhibition of airway narrowing. However, DIs taken before methacholine challenge limit airway responsiveness only when a test of lung function requiring a DI is used (FEV1). Therefore, it has been suggested that prior DIs enhance the compliance of the airways or airway smooth muscle (ASM). This would increase the strain the airway wall undergoes during the subsequent DI, which is part of the FEV1 maneuver. To investigate this phenomenon, we used ovine tracheal smooth muscle strips that were subjected to shortening elicited by acetylcholine with or without prior strain mimicking two DIs. The compliance of the shortened strip was then measured in response to a stress mimicking one DI. Our results show that the presence of "DIs" before acetylcholine-induced shortening resulted in 11% greater relengthening in response to the third DI, compared with the prior DIs. This effect, although small, is shown to be potentially important for the reopening of closed airways. The effect of prior DIs was abolished by the adaptation of ASM to either shorter or longer lengths or to a low baseline tone. These results suggest that DIs confer bronchoprotection because they increase the compliance of ASM, which, consequently, promotes greater strain from subsequent DI and fosters the reopening of closed airways.

  8. Enhancing Electronic Nose Performance Based on a Novel QPSO-KELM Model

    Directory of Open Access Journals (Sweden)

    Chao Peng

    2016-04-01

    Full Text Available A novel multi-class classification method for bacteria detection termed quantum-behaved particle swarm optimization-based kernel extreme learning machine (QPSO-KELM based on an electronic nose (E-nose technology is proposed in this paper. Time and frequency domain features are extracted from E-nose signals used for detecting four different classes of wounds (uninfected and infected with Staphylococcu aureus, Escherichia coli and Pseudomonas aeruginosa in this experiment. In addition, KELM is compared with five existing classification methods: Linear discriminant analysis (LDA, quadratic discriminant analysis (QDA, extreme learning machine (ELM, k-nearest neighbor (KNN and support vector machine (SVM. Meanwhile, three traditional optimization methods including particle swarm optimization algorithm (PSO, genetic algorithm (GA and grid search algorithm (GS and four kernel functions (Gaussian kernel, linear kernel, polynomial kernel and wavelet kernel for KELM are discussed in this experiment. Finally, the QPSO-KELM model is also used to deal with another two experimental E-nose datasets in the previous experiments. The experimental results demonstrate the superiority of QPSO-KELM in various E-nose applications.

  9. Enhancing Electronic Nose Performance Based on a Novel QPSO-KELM Model.

    Science.gov (United States)

    Peng, Chao; Yan, Jia; Duan, Shukai; Wang, Lidan; Jia, Pengfei; Zhang, Songlin

    2016-04-11

    A novel multi-class classification method for bacteria detection termed quantum-behaved particle swarm optimization-based kernel extreme learning machine (QPSO-KELM) based on an electronic nose (E-nose) technology is proposed in this paper. Time and frequency domain features are extracted from E-nose signals used for detecting four different classes of wounds (uninfected and infected with Staphylococcu aureus, Escherichia coli and Pseudomonas aeruginosa) in this experiment. In addition, KELM is compared with five existing classification methods: Linear discriminant analysis (LDA), quadratic discriminant analysis (QDA), extreme learning machine (ELM), k-nearest neighbor (KNN) and support vector machine (SVM). Meanwhile, three traditional optimization methods including particle swarm optimization algorithm (PSO), genetic algorithm (GA) and grid search algorithm (GS) and four kernel functions (Gaussian kernel, linear kernel, polynomial kernel and wavelet kernel) for KELM are discussed in this experiment. Finally, the QPSO-KELM model is also used to deal with another two experimental E-nose datasets in the previous experiments. The experimental results demonstrate the superiority of QPSO-KELM in various E-nose applications.

  10. Electronic Nose Testing Procedure for the Definition of Minimum Performance Requirements for Environmental Odor Monitoring.

    Science.gov (United States)

    Eusebio, Lidia; Capelli, Laura; Sironi, Selena

    2016-09-21

    Despite initial enthusiasm towards electronic noses and their possible application in different fields, and quite a lot of promising results, several criticalities emerge from most published research studies, and, as a matter of fact, the diffusion of electronic noses in real-life applications is still very limited. In general, a first step towards large-scale-diffusion of an analysis method, is standardization. The aim of this paper is describing the experimental procedure adopted in order to evaluate electronic nose performances, with the final purpose of establishing minimum performance requirements, which is considered to be a first crucial step towards standardization of the specific case of electronic nose application for environmental odor monitoring at receptors. Based on the experimental results of the performance testing of a commercialized electronic nose type with respect to three criteria (i.e., response invariability to variable atmospheric conditions, instrumental detection limit, and odor classification accuracy), it was possible to hypothesize a logic that could be adopted for the definition of minimum performance requirements, according to the idea that these are technologically achievable.

  11. Electronic Nose Testing Procedure for the Definition of Minimum Performance Requirements for Environmental Odor Monitoring

    Directory of Open Access Journals (Sweden)

    Lidia Eusebio

    2016-09-01

    Full Text Available Despite initial enthusiasm towards electronic noses and their possible application in different fields, and quite a lot of promising results, several criticalities emerge from most published research studies, and, as a matter of fact, the diffusion of electronic noses in real-life applications is still very limited. In general, a first step towards large-scale-diffusion of an analysis method, is standardization. The aim of this paper is describing the experimental procedure adopted in order to evaluate electronic nose performances, with the final purpose of establishing minimum performance requirements, which is considered to be a first crucial step towards standardization of the specific case of electronic nose application for environmental odor monitoring at receptors. Based on the experimental results of the performance testing of a commercialized electronic nose type with respect to three criteria (i.e., response invariability to variable atmospheric conditions, instrumental detection limit, and odor classification accuracy, it was possible to hypothesize a logic that could be adopted for the definition of minimum performance requirements, according to the idea that these are technologically achievable.

  12. Diverse Applications of Electronic-Nose Technologies in Agriculture and Forestry

    Directory of Open Access Journals (Sweden)

    Alphus D. Wilson

    2013-02-01

    Full Text Available Electronic-nose (e-nose instruments, derived from numerous types of aroma-sensor technologies, have been developed for a diversity of applications in the broad fields of agriculture and forestry. Recent advances in e-nose technologies within the plant sciences, including improvements in gas-sensor designs, innovations in data analysis and pattern-recognition algorithms, and progress in material science and systems integration methods, have led to significant benefits to both industries. Electronic noses have been used in a variety of commercial agricultural-related industries, including the agricultural sectors of agronomy, biochemical processing, botany, cell culture, plant cultivar selections, environmental monitoring, horticulture, pesticide detection, plant physiology and pathology. Applications in forestry include uses in chemotaxonomy, log tracking, wood and paper processing, forest management, forest health protection, and waste management. These aroma-detection applications have improved plant-based product attributes, quality, uniformity, and consistency in ways that have increased the efficiency and effectiveness of production and manufacturing processes. This paper provides a comprehensive review and summary of a broad range of electronic-nose technologies and applications, developed specifically for the agriculture and forestry industries over the past thirty years, which have offered solutions that have greatly improved worldwide agricultural and agroforestry production systems.

  13. Computer Aided Design and Stress Analysis of Nose Landing Gear Barrel (NLGB

    Directory of Open Access Journals (Sweden)

    Sanjay Kumar Sardiwal

    2015-04-01

    Full Text Available During the conceptual design phase of aircraft the integration of undercarriage system is very important and it is often difficult to achieve on the first time. The nose wheel landing gear preferred configurations for light naval trainer aircraft. The main objective of this project is to improve the static strength criteria and fatigue life of Nose Landing Gear Barrel considered. The investigations includes preliminary design layout for Nose Landing Gear Barrel and initial sizing has been done. It has been designed and evaluated for strength criteria. A method of analysis for the design of Nose Landing Gear Barrel made up of Al-Cu alloy (BS L 168 T6511 with static loads of axial, bending and normal loads are applied. The geometric modeling of the Nose Landing Gear Barrel was carried out using CAD package CATIA V5 R19 and pre and post processing was done through MSC/PATRAN. The stresses and displacements are obtained with the application of MSC/NASTRAN finite element software.

  14. An improved approach to identify irradiated spices using electronic nose, FTIR, and EPR spectroscopy.

    Science.gov (United States)

    Sanyal, Bhaskar; Ahn, Jae-Jun; Maeng, Jeong-Hwan; Kyung, Hyun-Kyu; Lim, Ha-Kyeong; Sharma, Arun; Kwon, Joong-Ho

    2014-09-01

    Changes in cumin and chili powder from India resulting from electron-beam irradiation were investigated using 3 analytical methods: electronic nose (E-nose), Fourier transform infrared (FTIR) spectroscopy, and electron paramagnetic resonance (EPR) spectroscopy. The spices had been exposed to 6 to 14 kGy doses recommended for microbial decontamination. E-nose measured a clear difference in flavor patterns of the irradiated spices in comparison with the nonirradiated samples. Principal component analysis further showed a dose-dependent variation. FTIR spectra of the samples showed strong absorption bands at 3425, 3007 to 2854, and 1746 cm(-1). However, both nonirradiated and irradiated spice samples had comparable patterns without any noteworthy changes in functional groups. EPR spectroscopy of the irradiated samples showed a radiation-specific triplet signal at g = 2.006 with a hyper-fine coupling constant of 3 mT confirming the results obtained with the E-nose technique. Thus, E-nose was found to be a potential tool to identify irradiated spices.

  15. Electronic nose guided determination of frying disposal time of sunflower oil using fuzzy logic analysis.

    Science.gov (United States)

    Upadhyay, Rohit; Sehwag, Sneha; Mishra, Hari Niwas

    2017-04-15

    An electronic nose (e-nose), having 18 metal oxide semiconductor (MOS) sensors, guided determination of frying disposal time of sunflower oil is reported. The ranking and screening of MOS sensors, specific for volatile organic compounds, was performed using fuzzy logic. A correlation was examined between rancidity indices of fried oil (total polar compounds (TPC), and triglyceride dimers-polymers (TGDP), among others) and e-nose based odor index. Fuzzy logic screened 6 MOS sensors (LY2/G, LY2/AA, LY2/GH, LY2/gCT1, T30/1, and P30/1) to deconvolute the rancid fried oils using hierarchical clustering on principal component space. A good relationship was noted between rancidity indices and odor index (R(2)>0.85). Based on maximum discard limits of rancidity indices (25% TPC and 10% TGDP), the frying disposal time of 15.2h (TPC) vs. 15.8h (e-nose) and 15.5h (TGDP) vs. 16.3h (e-nose) was determined. The demonstrated methodology holds a potential extension to different fried oils and products.

  16. An Electronic Nose for Reliable Measurement and Correct Classification of Beverages

    Directory of Open Access Journals (Sweden)

    Mahammad A. Hannan

    2011-06-01

    Full Text Available This paper reports the design of an electronic nose (E-nose prototype for reliable measurement and correct classification of beverages. The prototype was developed and fabricated in the laboratory using commercially available metal oxide gas sensors and a temperature sensor. The repeatability, reproducibility and discriminative ability of the developed E-nose prototype were tested on odors emanating from different beverages such as blackcurrant juice, mango juice and orange juice, respectively. Repeated measurements of three beverages showed very high correlation (r > 0.97 between the same beverages to verify the repeatability. The prototype also produced highly correlated patterns (r > 0.97 in the measurement of beverages using different sensor batches to verify its reproducibility. The E-nose prototype also possessed good discriminative ability whereby it was able to produce different patterns for different beverages, different milk heat treatments (ultra high temperature, pasteurization and fresh and spoiled milks. The discriminative ability of the E-nose was evaluated using Principal Component Analysis and a Multi Layer Perception Neural Network, with both methods showing good classification results.

  17. Diverse applications of electronic-nose technologies in agriculture and forestry.

    Science.gov (United States)

    Wilson, Alphus D

    2013-02-08

    Electronic-nose (e-nose) instruments, derived from numerous types of aroma-sensor technologies, have been developed for a diversity of applications in the broad fields of agriculture and forestry. Recent advances in e-nose technologies within the plant sciences, including improvements in gas-sensor designs, innovations in data analysis and pattern-recognition algorithms, and progress in material science and systems integration methods, have led to significant benefits to both industries. Electronic noses have been used in a variety of commercial agricultural-related industries, including the agricultural sectors of agronomy, biochemical processing, botany, cell culture, plant cultivar selections, environmental monitoring, horticulture, pesticide detection, plant physiology and pathology. Applications in forestry include uses in chemotaxonomy, log tracking, wood and paper processing, forest management, forest health protection, and waste management. These aroma-detection applications have improved plant-based product attributes, quality, uniformity, and consistency in ways that have increased the efficiency and effectiveness of production and manufacturing processes. This paper provides a comprehensive review and summary of a broad range of electronic-nose technologies and applications, developed specifically for the agriculture and forestry industries over the past thirty years, which have offered solutions that have greatly improved worldwide agricultural and agroforestry production systems.

  18. Diverse Applications of Electronic-Nose Technologies in Agriculture and Forestry

    Science.gov (United States)

    Wilson, Alphus D.

    2013-01-01

    Electronic-nose (e-nose) instruments, derived from numerous types of aroma-sensor technologies, have been developed for a diversity of applications in the broad fields of agriculture and forestry. Recent advances in e-nose technologies within the plant sciences, including improvements in gas-sensor designs, innovations in data analysis and pattern-recognition algorithms, and progress in material science and systems integration methods, have led to significant benefits to both industries. Electronic noses have been used in a variety of commercial agricultural-related industries, including the agricultural sectors of agronomy, biochemical processing, botany, cell culture, plant cultivar selections, environmental monitoring, horticulture, pesticide detection, plant physiology and pathology. Applications in forestry include uses in chemotaxonomy, log tracking, wood and paper processing, forest management, forest health protection, and waste management. These aroma-detection applications have improved plant-based product attributes, quality, uniformity, and consistency in ways that have increased the efficiency and effectiveness of production and manufacturing processes. This paper provides a comprehensive review and summary of a broad range of electronic-nose technologies and applications, developed specifically for the agriculture and forestry industries over the past thirty years, which have offered solutions that have greatly improved worldwide agricultural and agroforestry production systems. PMID:23396191

  19. Electronic Nose Testing Procedure for the Definition of Minimum Performance Requirements for Environmental Odor Monitoring

    Science.gov (United States)

    Eusebio, Lidia; Capelli, Laura; Sironi, Selena

    2016-01-01

    Despite initial enthusiasm towards electronic noses and their possible application in different fields, and quite a lot of promising results, several criticalities emerge from most published research studies, and, as a matter of fact, the diffusion of electronic noses in real-life applications is still very limited. In general, a first step towards large-scale-diffusion of an analysis method, is standardization. The aim of this paper is describing the experimental procedure adopted in order to evaluate electronic nose performances, with the final purpose of establishing minimum performance requirements, which is considered to be a first crucial step towards standardization of the specific case of electronic nose application for environmental odor monitoring at receptors. Based on the experimental results of the performance testing of a commercialized electronic nose type with respect to three criteria (i.e., response invariability to variable atmospheric conditions, instrumental detection limit, and odor classification accuracy), it was possible to hypothesize a logic that could be adopted for the definition of minimum performance requirements, according to the idea that these are technologically achievable. PMID:27657086

  20. High resolution electron energy loss spectroscopy of narrow gap III-V semiconductor surfaces and interfaces

    CERN Document Server

    Veal, T D

    2002-01-01

    The electronic properties of n-type narrow gap III-V semiconductor surfaces and interfaces are investigated using high-resolution electron-energy-loss spectroscopy (HREELS). Changing the incident electron energy, alters the wave-vector transfer parallel to the surface, allowing the probing depth to be varied over typical space-charge layer widths (100 - 2000 A). Semi-classical dielectric theory simulations of the HREEL spectra are performed to extract quantitative information from the probing energy-dependence of the surface plasmon and phonon peaks. The plasma frequency used in the simulations is related to the electron concentration and effective mass using the Kane model of the non-parabolic conduction band. Space-charge layer parameters are obtained by comparing calculated smooth charge profiles with the histogram profiles that are used in the simulations. Complementary experimental techniques are employed to correlate the reconstruction, chemical composition and morphology of the surface with the electro...

  1. Vortex formation in magnetic narrow rings

    Science.gov (United States)

    Bland, J. A. C.

    2002-03-01

    Underlying the current interest in magnetic elements is the possibility such systems provide both for the study of fundamental phenomena in magnetism (such as domain wall trapping and spin switching) and for technological applications, such as high density magnetic storage or magnetic random access memories (MRAM). One key issue is to control the magnetic switching precisely. To achieve this one needs first to have a well defined and reproducible remanent state, and second the switching process itself must be simple and reproducible. Among the many studied geometries, rings are shown to exhibit several advantages over other geometries, in that they show relatively simple stable magnetic states at remanence, with fast and simple magnetisation switching mechanisms. This is borne out of our systematic investigation of the magnetic properties of epitaxial and polycrystalline Co rings, where both the static, dynamic and transport properties have been studied. Magnetic measurements and micromagnetic simulations show that for appropriate ring structures a two step switching process occurs at high fields, indicating the existence of two different stable states. In addition to the vortex state, which occurs at intermediate fields, we have identified a new bi-domain state, which we term the `onion state', corresponding to opposite circulation of the magnetisation in each half of the ring. The magnetic elements were fabricated using a new technique based on the pre-patterning of Si ring structures and subsequent epitaxial growth of Cu/Co/Cu sandwich films on top of the Si elements. This technique has allowed the growth of epitaxial fcc Co(001) structures and in contrast to conventional lithographic methods, no damage to the magnetic layer structure is introduced by the patterning process [1,2]. We have studied the magnetic switching properties of arrays of narrow Co(100) epitaxial ring magnets, with outer diameters between 1 μm and 2 μm, varying inner diameters and varying

  2. Nonequilibrium flows with smooth particle applied mechanics

    Energy Technology Data Exchange (ETDEWEB)

    Kum, Oyeon [Univ. of California, Davis, CA (United States)

    1995-07-01

    Smooth particle methods are relatively new methods for simulating solid and fluid flows through they have a 20-year history of solving complex hydrodynamic problems in astrophysics, such as colliding planets and stars, for which correct answers are unknown. The results presented in this thesis evaluate the adaptability or fitness of the method for typical hydrocode production problems. For finite hydrodynamic systems, boundary conditions are important. A reflective boundary condition with image particles is a good way to prevent a density anomaly at the boundary and to keep the fluxes continuous there. Boundary values of temperature and velocity can be separately controlled. The gradient algorithm, based on differentiating the smooth particle expression for (uρ) and (Tρ), does not show numerical instabilities for the stress tensor and heat flux vector quantities which require second derivatives in space when Fourier`s heat-flow law and Newton`s viscous force law are used. Smooth particle methods show an interesting parallel linking to them to molecular dynamics. For the inviscid Euler equation, with an isentropic ideal gas equation of state, the smooth particle algorithm generates trajectories isomorphic to those generated by molecular dynamics. The shear moduli were evaluated based on molecular dynamics calculations for the three weighting functions, B spline, Lucy, and Cusp functions. The accuracy and applicability of the methods were estimated by comparing a set of smooth particle Rayleigh-Benard problems, all in the laminar regime, to corresponding highly-accurate grid-based numerical solutions of continuum equations. Both transient and stationary smooth particle solutions reproduce the grid-based data with velocity errors on the order of 5%. The smooth particle method still provides robust solutions at high Rayleigh number where grid-based methods fails.

  3. The Case for the Narrow View of Reading

    Science.gov (United States)

    Kamhi, Alan G.

    2009-01-01

    Purpose: This prologue reiterates the case for the narrow view of reading as a solution to the persistently high levels of reading failure that occurs in our schools and provides a brief summary of the 5 response articles. Method: The arguments that support the narrow view of reading are presented and the respondents are introduced. Conclusion:…

  4. Narrow band tuning with small long pulse excimer lasers

    Energy Technology Data Exchange (ETDEWEB)

    Sze, R.C.; Kurnit, N.; Watkins, D.; Bigio, I.

    1985-12-01

    We discuss frequency narrowing and tuning with simple dispersion elements with small long-pulse excimer lasers. The improved performance over short-pulse lasers is discussed and attributed to the increased number of round trips. A physical model of the dynamics of line narrowing is presented.

  5. Bayesian Face Recognition and Perceptual Narrowing in Face-Space

    Science.gov (United States)

    Balas, Benjamin

    2012-01-01

    During the first year of life, infants' face recognition abilities are subject to "perceptual narrowing", the end result of which is that observers lose the ability to distinguish previously discriminable faces (e.g. other-race faces) from one another. Perceptual narrowing has been reported for faces of different species and different races, in…

  6. Channel Narrowing and Channel Reset: Effects of a Large Flood on the Vegetated, Narrowing Rio Grande

    Science.gov (United States)

    Dean, D. J.; Schmidt, J. C.

    2009-12-01

    In September 2008, heavy precipitation from a tropical storm in the Sierra Madre Occidental, MX, produced large amounts of stream flow to the Rio Conchos and lower Rio Grande. This flood was well publicized in the media due to the widespread flooding in Ojinaga, Chih., and Presidio, TX. Gage records indicate that this flood had an approximate recurrence of 15 years as measured on the Rio Grande near Presidio. Nevertheless, flood stages were the highest ever recorded and resulted from a significant loss of channel capacity due to channel narrowing that had occurred during the previous 18 years. Measurements from aerial photographs indicate that channel width had decreased between 35 and 50% between 1990 and 2008 during regional drought. During this period of low stream flow, invasion by non-native riparian vegetation (Tamarix spp., Arundo donax) helped trap sediment and promote floodplain accretion. Our resurveys of the channel indicate that the 2008 flood was a reset event and that the channel was re-widened by 32 to 48%. Repeated, oblique photographs showed significant channel migration and large scale floodplain stripping during this flood. These results show that although riparian vegetation may actively promote channel narrowing and floodplain accretion, moderately large floods may cause large scale bank erosion, floodplain stripping, and vegetation removal in alluvial valleys subject to large-scale invasion by nonnative plants.

  7. Smoothing methods in biometry: a historic review

    Directory of Open Access Journals (Sweden)

    Schimek, Michael G.

    2005-06-01

    Full Text Available In Germany around 25 years ago nonparametric smoothing methods have found their way into statistics and with some delay also into biometry. In the early 1980's there has been what one might call a boom in theoretical and soon after also in computational statistics. The focus was on univariate nonparametric methods for density and curve estimation. For biometry however smoothing methods became really interesting in their multivariate version. This 'change of dimensionality' is still raising open methodological questions. No wonder that the simplifying paradigm of additive regression, realized in the generalized additive models (GAM, has initiated the success story of smoothing techniques starting in the early 1990's. In parallel there have been new algorithms and important software developments, primarily in the statistical programming languages S and R. Recent developments of smoothing techniques can be found in survival analysis, longitudinal analysis, mixed models and functional data analysis, partly integrating Bayesian concepts. All new are smoothing related statistical methods in bioinformatics. In this article we aim not only at a general historical overview but also try to sketch activities in the German-speaking world. Moreover, the current situation is critically examined. Finally a large number of relevant references is given.

  8. Airway hyperresponsiveness; smooth muscle as the principal actor [version 1; referees: 2 approved

    Directory of Open Access Journals (Sweden)

    Anne-Marie Lauzon

    2016-03-01

    Full Text Available Airway hyperresponsiveness (AHR is a defining characteristic of asthma that refers to the capacity of the airways to undergo exaggerated narrowing in response to stimuli that do not result in comparable degrees of airway narrowing in healthy subjects. Airway smooth muscle (ASM contraction mediates airway narrowing, but it remains uncertain as to whether the smooth muscle is intrinsically altered in asthmatic subjects or is responding abnormally as a result of the milieu in which it sits. ASM in the trachea or major bronchi does not differ in its contractile characteristics in asthmatics, but the more pertinent peripheral airways await complete exploration. The mass of ASM is increased in many but not all asthmatics and therefore cannot be a unifying hypothesis for AHR, although when increased in mass it may contribute to AHR. The inability of a deep breath to reverse or prevent bronchial narrowing in asthma may reflect an intrinsic difference in the mechanisms that lead to softening of contracted ASM when subjected to stretch. Cytokines such as interleukin-13 and tumor necrosis factor-α promote a more contractile ASM phenotype. The composition and increased stiffness of the matrix in which ASM is embedded promotes a more proliferative and pro-inflammatory ASM phenotype, but the expected dedifferentiation and loss of contractility have not been shown. Airway epithelium may drive ASM proliferation and/or molecular remodeling in ways that may lead to AHR. In conclusion, AHR is likely multifactorial in origin, reflecting the plasticity of ASM properties in the inflammatory environment of the asthmatic airway.

  9. A Solid Trap and Thermal Desorption System with Application to a Medical Electronic Nose

    Directory of Open Access Journals (Sweden)

    Xuntao Xu

    2008-11-01

    Full Text Available In this paper, a solid trap/thermal desorption-based odorant gas condensation system has been designed and implemented for measuring low concentration odorant gas. The technique was successfully applied to a medical electronic nose system. The developed system consists of a flow control unit, a temperature control unit and a sorbent tube. The theoretical analysis and experimental results indicate that gas condensation, together with the medical electronic nose system can significantly reduce the detection limit of the nose system and increase the system’s ability to distinguish low concentration gas samples. In addition, the integrated system can remove the influence of background components and fluctuation of operational environment. Even with strong disturbances such as water vapour and ethanol gas, the developed system can classify the test samples accurately.

  10. The role of septal surgery in management of the deviated nose.

    Science.gov (United States)

    Foda, Hossam M T

    2005-02-01

    The deviated nose represents a complex cosmetic and functional problem. Septal surgery plays a central role in the successful management of the externally deviated nose. This study included 260 patients seeking rhinoplasty to correct external nasal deviations; 75 percent of them had various degrees of nasal obstruction. Septal surgery was necessary in 232 patients (89 percent), not only to improve breathing but also to achieve a straight, symmetrical, external nose as well. A graduated surgical approach was adopted to allow correction of the dorsal and caudal deviations of the nasal septum without weakening its structural support to the dorsum or nasal tip. The approach depended on full mobilization of deviated cartilage, followed by straightening of the cartilage and its fixation in the corrected position by using bony splinting grafts through an external rhinoplasty approach.

  11. Analysis of normal shock noise measurements on nose-cylinder bodies.

    Science.gov (United States)

    Reding, J. P.; Guenther, R. A.

    1972-01-01

    Aerodynamic noise measurements have been obtained on three nose-cylinder configurations (15 deg cone-cylinder, biconic nose-cylinder and biconic nose-corrogated cylinder) in transonic flow. The noise environment at the foot of the terminal normal shock and its associated separated flow bubble were examined in detail. A peak in the frequency spectra of the separated flow region was observed which compares well with the predicted resonance frequency of the separated pocket using Trilling's incident shock model. As a consequence of the observed sound spectra and noise level, a flow model is postulated which consist of a cellular separated flow region. In the central portion of the cell the flow resembles the classical two-dimensional recirculating bubble, but each cell is vented by a pair of counter rotating vortices, which start at the surface and steam downstream.

  12. Adenocarcinoma of the nose and paranasal sinuses in woodworkers in the state of Victoria, Australia.

    Science.gov (United States)

    Ironside, P; Matthews, J

    1975-09-01

    The case index of the Cancer Institute of Victoria (Australia) contained 19 cases of adenocarcinoma of the nose and paranasal sinuses. Eighteen of the cases were in men and 1 in a women. Routine questioning of these patients revealed an occupation involving woodworking in 7 cases, whereas among 80 cases of other malignant tumors of the nose and sinuses there were only 4 who had been woodworkers. Among the patients with adenocarcinoma of the nose and sinuses, there was a significantly higher proportion of woodworkers than in the general population. The findings are consistent with European reports associating nasal adenocarcinoma with wood dust, but whereas the workers at risk in Europe are mainly in the furniture industry, some of the workers affected in Victoria have been sawmillers or carpenters. The specific salivary patterns of tumors of mucous glands are not associated with woodworking.

  13. Application of Electronic Noses for Disease Diagnosis and Food Spoilage Detection

    Directory of Open Access Journals (Sweden)

    Paolo Di Francesco

    2006-11-01

    Full Text Available Over the last twenty years, newly developed chemical sensor systems (socalled“electronic noses" have odour analyses made possible. This paper describes theapplications of these systems for microbial detection in different fields such as medicineand the food industry, where fast detection methods are essential for appropriatemanagement of health care. Several groups have employed different electronic noses forclassification and quantification of bacteria and fungi to obtain accurate medicaldiagnosis and food quality control. So far, detection and identification of bacterial andfungal volatiles have been achieved by use of e-noses offering different correctclassification percentages. The present review includes examples of bacterial and fungalspecies producing volatile compounds and correlated to infectious diseases or fooddeterioration. The results suggest the possibility of using this new technology both inmedical diagnostics and in food control management.

  14. Suppression of Strong Background Interference on E-Nose Sensors in an Open Country Environment.

    Science.gov (United States)

    Tian, Fengchun; Zhang, Jian; Yang, Simon X; Zhao, Zhenzhen; Liang, Zhifang; Liu, Yan; Wang, Di

    2016-02-16

    The feature extraction technique for an electronic nose (e-nose) applied in tobacco smell detection in an open country/outdoor environment with periodic background strong interference is studied in this paper. Principal component analysis (PCA), Independent component analysis (ICA), re-filtering and a priori knowledge are combined to separate and suppress background interference on the e-nose. By the coefficient of multiple correlation (CMC), it can be verified that a better separation of environmental temperature, humidity, and atmospheric pressure variation related background interference factors can be obtained with ICA. By re-filtering according to the on-site interference characteristics a composite smell curve was obtained which is more related to true smell information based on the tobacco curer's experience.

  15. Electronic Nose: A Promising Tool For Early Detection Of Alicyclobacillus spp In Soft Drinks

    Science.gov (United States)

    Concina, I.; Bornšek, M.; Baccelliere, S.; Falasconi, M.; Sberveglieri, G.

    2009-05-01

    In the present work we investigate the potential use of the Electronic Nose EOS835 (SACMI scarl, Italy) to early detect Alicyclobacillus spp in two flavoured soft drinks. These bacteria have been acknowledged by producer companies as a major quality control target microorganisms because of their ability to survive commercial pasteurization processes and produce taint compounds in final product. Electronic Nose was able to distinguish between uncontaminated and contaminated products before the taint metabolites were identifiable by an untrained panel. Classification tests showed an excellent rate of correct classification for both drinks (from 86% uo to 100%). High performance liquid chromatography analyses showed no presence of the main metabolite at a level of 200 ppb, thus confirming the skill of the Electronic Nose technology in performing an actual early diagnosis of contamination.

  16. A Novel Wearable Electronic Nose for Healthcare Based on Flexible Printed Chemical Sensor Array

    Directory of Open Access Journals (Sweden)

    Panida Lorwongtragool

    2014-10-01

    Full Text Available A novel wearable electronic nose for armpit odor analysis is proposed by using a low-cost chemical sensor array integrated in a ZigBee wireless communication system. We report the development of a carbon nanotubes (CNTs/polymer sensor array based on inkjet printing technology. With this technique both composite-like layer and actual composite film of CNTs/polymer were prepared as sensing layers for the chemical sensor array. The sensor array can response to a variety of complex odors and is installed in a prototype of wearable e-nose for monitoring the axillary odor released from human body. The wearable e-nose allows the classification of different armpit odors and the amount of the volatiles released as a function of level of skin hygiene upon different activities.

  17. A Novel Wearable Electronic Nose for Healthcare Based on Flexible Printed Chemical Sensor Array

    Science.gov (United States)

    Lorwongtragool, Panida; Sowade, Enrico; Watthanawisuth, Natthapol; Baumann, Reinhard R.; Kerdcharoen, Teerakiat

    2014-01-01

    A novel wearable electronic nose for armpit odor analysis is proposed by using a low-cost chemical sensor array integrated in a ZigBee wireless communication system. We report the development of a carbon nanotubes (CNTs)/polymer sensor array based on inkjet printing technology. With this technique both composite-like layer and actual composite film of CNTs/polymer were prepared as sensing layers for the chemical sensor array. The sensor array can response to a variety of complex odors and is installed in a prototype of wearable e-nose for monitoring the axillary odor released from human body. The wearable e-nose allows the classification of different armpit odors and the amount of the volatiles released as a function of level of skin hygiene upon different activities. PMID:25340447

  18. Smooth muscle actin and myosin expression in cultured airway smooth muscle cells.

    Science.gov (United States)

    Wong, J Z; Woodcock-Mitchell, J; Mitchell, J; Rippetoe, P; White, S; Absher, M; Baldor, L; Evans, J; McHugh, K M; Low, R B

    1998-05-01

    In this study, the expression of smooth muscle actin and myosin was examined in cultures of rat tracheal smooth muscle cells. Protein and mRNA analyses demonstrated that these cells express alpha- and gamma-smooth muscle actin and smooth muscle myosin and nonmuscle myosin-B heavy chains. The expression of the smooth muscle specific actin and myosin isoforms was regulated in the same direction when growth conditions were changed. Thus, at confluency in 1 or 10% serum-containing medium as well as for low-density cells (50-60% confluent) deprived of serum, the expression of the smooth muscle forms of actin and myosin was relatively high. Conversely, in rapidly proliferating cultures at low density in 10% serum, smooth muscle contractile protein expression was low. The expression of nonmuscle myosin-B mRNA and protein was more stable and was upregulated only to a small degree in growing cells. Our results provide new insight into the molecular basis of differentiation and contractile function in airway smooth muscle cells.

  19. Using the Electronic Nose to Identify Airway Infection during COPD Exacerbations.

    Directory of Open Access Journals (Sweden)

    Hanaa Shafiek

    Full Text Available The electronic nose (e-nose detects volatile organic compounds (VOCs in exhaled air. We hypothesized that the exhaled VOCs print is different in stable vs. exacerbated patients with chronic obstructive pulmonary disease (COPD, particularly if the latter is associated with airway bacterial infection, and that the e-nose can distinguish them.Smell-prints of the bacteria most commonly involved in exacerbations of COPD (ECOPD were identified in vitro. Subsequently, we tested our hypothesis in 93 patients with ECOPD, 19 of them with pneumonia, 50 with stable COPD and 30 healthy controls in a cross-sectional case-controlled study. Secondly, ECOPD patients were re-studied after 2 months if clinically stable. Exhaled air was collected within a Tedlar bag and processed by a Cynarose 320 e-nose. Breath-prints were analyzed by Linear Discriminant Analysis (LDA with "One Out" technique and Sensor logic Relations (SLR. Sputum samples were collected for culture.ECOPD with evidence of infection were significantly distinguishable from non-infected ECOPD (p = 0.018, with better accuracy when ECOPD was associated to pneumonia. The same patients with ECOPD were significantly distinguishable from stable COPD during follow-up (p = 0.018, unless the patient was colonized. Additionally, breath-prints from COPD patients were significantly distinguished from healthy controls. Various bacteria species were identified in culture but the e-nose was unable to identify accurately the bacteria smell-print in infected patients.E-nose can identify ECOPD, especially if associated with airway bacterial infection or pneumonia.

  20. Potential application of electronic nose in processed animal proteins (PAP detection in feedstuffs

    Directory of Open Access Journals (Sweden)

    Dell'Orto V.

    2004-01-01

    Full Text Available Electronic nose and olfactometry techniques represent a modern analytical approach in food industry since they could potentially improve quality and safety of food processing. The aim of this study was to evaluate possible application of electronic nose in PA P detection and recognition in feed. For this purpose 6 reference feedstuffs (CRA-W / UE STRAT F E E D Project were used. The basis of the test samples was a compound feed for bovine fortified with processed animal proteins ( PAP consisting of meat and bone meal (MBM and/or fish meal at different concentrations. Each feed sample was tested in glass vials and the odour profile was determined by the ten MOS (metal oxide semi-conductor sensors of the electronic nose. Ten different descriptors, representing each ten sensors of electronic nose, were used to characterise the odour of each sample. In the present study, electronic nose was able to discriminate the blank sample from all other samples containing PA P ( M B M , fish meal or both. Samples containing either 0.5% of MBM or 5% of fish meal were identified, while samples containing a high fish meal content (5% associated with a low MBM content (0.5% were not discriminated from samples containing solely fish meal at that same high level (5%. This latter indicates that probably the high fish meal level, in samples containing both MBM and fish meal, tended to mask MBM odour. It was also evident that two odour descriptors were enough to explain 72.12% of total variability in odour pattern. In view of these results, it could be suggested that electronic nose and olfactometry techniques can provide an interesting approach for screening raw materials in feed industry, even though further studies using a wider set of samples are needed.

  1. Distribution Estimation with Smoothed Auxiliary Information

    Institute of Scientific and Technical Information of China (English)

    Xu Liu; Ahmad Ishfaq

    2011-01-01

    Distribution estimation is very important in order to make statistical inference for parameters or its functions based on this distribution. In this work we propose an estimator of the distribution of some variable with non-smooth auxiliary information, for example, a symmetric distribution of this variable. A smoothing technique is employed to handle the non-differentiable function. Hence, a distribution can be estimated based on smoothed auxiliary information. Asymptotic properties of the distribution estimator are derived and analyzed.The distribution estimators based on our method are found to be significantly efficient than the corresponding estimators without these auxiliary information. Some simulation studies are conducted to illustrate the finite sample performance of the proposed estimators.

  2. Archetypal oscillator for smooth and discontinuous dynamics.

    Science.gov (United States)

    Cao, Qingjie; Wiercigroch, Marian; Pavlovskaia, Ekaterina E; Grebogi, Celso; Thompson, J Michael T

    2006-10-01

    We propose an archetypal system to investigate transitions from smooth to discontinuous dynamics. In the smooth regime, the system bears significant similarities to the Duffing oscillator, exhibiting the standard dynamics governed by the hyperbolic structure associated with the stationary state of the double well. At the discontinuous limit, however, there is a substantial departure in the dynamics from the standard one. In particular, the velocity flow suffers a jump in crossing from one well to another, caused by the loss of local hyperbolicity due to the collapse of the stable and unstable manifolds of the stationary state. In the presence of damping and external excitation, the system has coexisting attractors and also a chaotic saddle which becomes a chaotic attractor when a smoothness parameter drops to zero. This attractor can bifurcate to a high-period periodic attractor or a chaotic sea with islands of quasiperiodic attractors depending on the strength of damping.

  3. Multiple predictor smoothing methods for sensitivity analysis.

    Energy Technology Data Exchange (ETDEWEB)

    Helton, Jon Craig; Storlie, Curtis B.

    2006-08-01

    The use of multiple predictor smoothing methods in sampling-based sensitivity analyses of complex models is investigated. Specifically, sensitivity analysis procedures based on smoothing methods employing the stepwise application of the following nonparametric regression techniques are described: (1) locally weighted regression (LOESS), (2) additive models, (3) projection pursuit regression, and (4) recursive partitioning regression. The indicated procedures are illustrated with both simple test problems and results from a performance assessment for a radioactive waste disposal facility (i.e., the Waste Isolation Pilot Plant). As shown by the example illustrations, the use of smoothing procedures based on nonparametric regression techniques can yield more informative sensitivity analysis results than can be obtained with more traditional sensitivity analysis procedures based on linear regression, rank regression or quadratic regression when nonlinear relationships between model inputs and model predictions are present.

  4. Application and comparison of band gap narrowing models for passivated phosphorus doped silicon surfaces

    Science.gov (United States)

    Kimmerle, Achim; Greulich, Johannes; Haug, Halvard; Wolf, Andreas

    2016-01-01

    In this work, the recently proposed band-gap narrowing model by Yan and Cuevas [J. Appl. Phys. 114, 044508 (2013)] is evaluated by simulations of the recombination pre-factor J0 of highly phosphorus doped, passivated crystalline silicon surfaces, which are particularly relevant for solar cell applications. The results were fitted to experimental J0 data measured on a large range of samples exhibiting different dopant profiles and passivation coatings, both for planar and textured surfaces. For each sample, the surface recombination velocity parameter Sp was extracted by fitting the simulation results to the experimental data. We show that the Yan and Cuevas' model developed for Fermi-Dirac statistics leads to a smooth and monotonically increasing curve for Sp as a function of the surface dopant concentration Nsurf, for both investigated passivation layers. We provide a parameterization for this relation and compare the findings with those obtained with the widely used model by Schenk [J. Appl. Phys. 84, 3684 (1998)]. On the other hand, we show that the apparent band gap narrowing of Yan and Cuevas developed for use with Boltzmann statistics cannot be used to describe the experimental data, requiring unphysical negative Sp values for high Nsurf.

  5. Semiconductor Sensor Array Based Electronic Nose for Milk, Rancid Milk and Yoghurt Odors Identification

    Science.gov (United States)

    Botre, B.; Gharpure, D.; Shaligram, A.; Sadistap, S.

    2009-05-01

    This paper presents the use semiconductor sensor array based electronic nose for the identification of milk, rancid milk and yoghurt odors. A low cost sensor array, serial data acquisition system and E-nose software package (ESP) tool are used to generate the database, feature extraction and normalization. The MLP NN is trained using the NeuroSolutions for the identification. The network has successfully classified milk, rancid milk and yoghurt odors with 96% success rate. A sensitivity analysis is done to test the performance of the sensor data in the trained network

  6. Thorns in armadillo ears and noses and their role in the transmission of leprosy.

    Science.gov (United States)

    Job, C K; Harris, E B; Allen, J L; Hastings, R C

    1986-11-01

    Both ears from 494 wild nine-banded armadillos (Dasypus novemcinctus) and nose specimens from 224 animals were collected and histopathologically studied. Lepromatous granulomas were present in the ear specimens of ten of 494 animals. There were thorns in the ears of 22.5% of animals, and in 36.6% of the nose specimens. In one armadillo, there was evidence to suggest that Mycobacterium leprae entered the tissue through the thorn pricks. In the normal habitat of the armadillo in Louisiana there are thorny bushes consisting mostly of the green briar and the southern dewberry. Thorn pricks as a means of transmission of leprosy in the wild armadillos is suggested.

  7. [Use of allogeneic septal cartilage in the correction of saddle nose].

    Science.gov (United States)

    Jakse, R; Wolfgruber, H

    1986-12-01

    It is reported about the intraseptal implantation of allogeneic cartilago quadrangularis for the correction of saddle nose in the case of eleven patients. The indication for the implantation were non sufficient residuals of the behind septum for a substitution plastic. The sagging of the noses was caused by iatrogenic in 6 and traumatic influences in 5 cases. The conservation of the septal cartilage was carried out in Cialit 1:5000. All the septa healed in without any reaction and obtained satisfactory functional and cosmetic results.

  8. A Novel Electronic Nose as Adaptable Device to Judge Microbiological Quality and Safety in Foodstuff

    OpenAIRE

    Sberveglieri, V.; Nunez Carmona, E.; Elisabetta Comini; Andrea Ponzoni; Dario Zappa; Onofrio Pirrotta; A. Pulvirenti

    2014-01-01

    This paper presents different applications, in various foodstuffs, by a novel electronic nose (EN) based on a mixed metal oxide sensors array composed of thin films as well as nanowires. The electronic nose used for this work has been done, starting from the commercial model EOS835 produced by SACMI Scarl. The SENSOR Lab (CNR-INO, Brescia) has produced both typologies of sensors, classical MOX and the new technologies with nanowire. The aim of this work was to test and to illustrate the b...

  9. Action on ileal smooth muscle of synthetic detergents and pardaxin.

    Science.gov (United States)

    Primor, N

    1986-01-01

    Pardaxin (PX), a toxic and repellent substance isolated from the Red Sea flatfish, causes a sharp ball-like profile of drop of saline placed on a hydrophobic film to turn into a flattened one. This effect results with a decrease of the contact angle (theta) from 96 degrees to a maximum of 42 degrees at 10(-4) M of PX. The action of sodium dodecyl sulphate (SDS), a synthetic anionic detergent, benzalkonium chloride (BAC) cationic detergent and pardaxin (PX) a toxic protein with detergent properties, were studied in the ileal guinea-pig longitudinal smooth muscle preparation. SDS (4 X 10(-4) M) and PX (5 X 10(-6) M) diminished the muscle contractile response to field stimulation (0.1 Hz, 1 msec) and to acetylcholine (Ach) and to histamine and elicited a prolonged (4-6 min) TTX-insensitive muscle contraction. The dose dependence of muscle contraction to SDS and PX was found to be sigmoidal and occurred over a narrow range of concentrations. The SDS- but not PX-induced muscle contraction could be reduced by diphenhydramine (H1 antihistamine). BAC (10(-5)-10(-4) M) suppressed the muscle's contractile response to electrical stimulation (0.1 Hz, 1 msec), to Ach, histamine and 5-hydroxytryptamine but did not produce muscle contraction. PX at concentrations higher than 5 X 10(-6) M is a potent detergent and at this concentration shares several pharmacological similarities with SDS.

  10. Evolutionary history of the odd-nosed monkeys and the phylogenetic position of the newly described Myanmar snub-nosed monkey Rhinopithecus strykeri.

    Science.gov (United States)

    Liedigk, Rasmus; Yang, Mouyu; Jablonski, Nina G; Momberg, Frank; Geissmann, Thomas; Lwin, Ngwe; Hla, Tony Htin; Liu, Zhijin; Wong, Bruce; Ming, Li; Yongcheng, Long; Zhang, Ya-Ping; Nadler, Tilo; Zinner, Dietmar; Roos, Christian

    2012-01-01

    Odd-nosed monkeys represent one of the two major groups of Asian colobines. Our knowledge about this primate group is still limited as it is highlighted by the recent discovery of a new species in Northern Myanmar. Although a common origin of the group is now widely accepted, the phylogenetic relationships among its genera and species, and the biogeographic processes leading to their current distribution are largely unknown. To address these issues, we have analyzed complete mitochondrial genomes and 12 nuclear loci, including one X chromosomal, six Y chromosomal and five autosomal loci, from all ten odd-nosed monkey species. The gene tree topologies and divergence age estimates derived from different markers were highly similar, but differed in placing various species or haplogroups within the genera Rhinopithecus and Pygathrix. Based on our data, Rhinopithecus represent the most basal lineage, and Nasalis and Simias form closely related sister taxa, suggesting a Northern origin of odd-nosed monkeys and a later invasion into Indochina and Sundaland. According to our divergence age estimates, the lineages leading to the genera Rhinopithecus, Pygathrix and Nasalis+Simias originated in the late Miocene, while differentiation events within these genera and also the split between Nasalis and Simias occurred in the Pleistocene. Observed gene tree discordances between mitochondrial and nuclear datasets, and paraphylies in the mitochondrial dataset for some species of the genera Rhinopithecus and Pygathrix suggest secondary gene flow after the taxa initially diverged. Most likely such events were triggered by dramatic changes in geology and climate within the region. Overall, our study provides the most comprehensive view on odd-nosed monkey evolution and emphasizes that data from differentially inherited markers are crucial to better understand evolutionary relationships and to trace secondary gene flow.

  11. Evolutionary history of the odd-nosed monkeys and the phylogenetic position of the newly described Myanmar snub-nosed monkey Rhinopithecus strykeri.

    Directory of Open Access Journals (Sweden)

    Rasmus Liedigk

    Full Text Available Odd-nosed monkeys represent one of the two major groups of Asian colobines. Our knowledge about this primate group is still limited as it is highlighted by the recent discovery of a new species in Northern Myanmar. Although a common origin of the group is now widely accepted, the phylogenetic relationships among its genera and species, and the biogeographic processes leading to their current distribution are largely unknown. To address these issues, we have analyzed complete mitochondrial genomes and 12 nuclear loci, including one X chromosomal, six Y chromosomal and five autosomal loci, from all ten odd-nosed monkey species. The gene tree topologies and divergence age estimates derived from different markers were highly similar, but differed in placing various species or haplogroups within the genera Rhinopithecus and Pygathrix. Based on our data, Rhinopithecus represent the most basal lineage, and Nasalis and Simias form closely related sister taxa, suggesting a Northern origin of odd-nosed monkeys and a later invasion into Indochina and Sundaland. According to our divergence age estimates, the lineages leading to the genera Rhinopithecus, Pygathrix and Nasalis+Simias originated in the late Miocene, while differentiation events within these genera and also the split between Nasalis and Simias occurred in the Pleistocene. Observed gene tree discordances between mitochondrial and nuclear datasets, and paraphylies in the mitochondrial dataset for some species of the genera Rhinopithecus and Pygathrix suggest secondary gene flow after the taxa initially diverged. Most likely such events were triggered by dramatic changes in geology and climate within the region. Overall, our study provides the most comprehensive view on odd-nosed monkey evolution and emphasizes that data from differentially inherited markers are crucial to better understand evolutionary relationships and to trace secondary gene flow.

  12. Several methods of smoothing motion capture data

    Science.gov (United States)

    Qi, Jingjing; Miao, Zhenjiang; Wang, Zhifei; Zhang, Shujun

    2011-06-01

    Human motion capture and editing technologies are widely used in computer animation production. We can acquire original motion data by human motion capture system, and then process it by motion editing system. However, noise embed in original motion data maybe introduced by extracting the target, three-dimensional reconstruction process, optimizing algorithm and devices itself in human motion capture system. The motion data must be modified before used to make videos, otherwise the animation figures will be jerky and their behavior is unnatural. Therefore, motion smoothing is essential. In this paper, we compare and summarize three methods of smoothing original motion capture data.

  13. Smooth models for the Coulomb potential

    CERN Document Server

    González-Espinoza, Cristina E; Karwowski, Jacek; Savin, Andreas

    2016-01-01

    Smooth model potentials with parameters selected to reproduce the spectrum of one-electron atoms are used to approximate the singular Coulomb potential. Even when the potentials do not mimic the Coulomb singularity, much of the spectrum is reproduced within the chemical accuracy. For the Hydrogen atom, the smooth approximations to the Coulomb potential are more accurate for higher angular momentum states. The transferability of the model potentials from an attractive interaction (Hydrogen atom) to a repulsive one (Harmonium and the uniform electron gas) is discussed.

  14. Production of super-smooth articles

    Energy Technology Data Exchange (ETDEWEB)

    Duchane, D.V.

    1981-05-29

    Super-smooth rounded or formed articles made of thermoplastic materials including various poly(methyl methacrylate) or acrylonitrile-butadiene-styrene copolymers are produced by immersing the articles into a bath, the composition of which is slowly changed with time. The starting composition of the bath is made up of at least one solvent for the polymer and a diluent made up of at least one nonsolvent for the polymer and optional materials which are soluble in the bath. The resulting extremely smooth articles are useful as mandrels for laser fusion and should be useful for a wide variety of other purposes, for example lenses.

  15. Nonlinear edge: preserving smoothing by PDEs

    Science.gov (United States)

    Ha, Yan; Liu, Jiejing

    2008-12-01

    This work introduces a new algorithm for image smoothing. Nonlinear partial differential equations (PDEs) are employed to smooth the image while preserving the edges and corners. Compared with other filters such as average filter and median filter, it is found that the effects of image denoising by the new algorithm are better than that by other filters. The experimental results show that this method can not only remove the noise but also preserve the edges and corners. Due to its simplicity and efficiency, the algorithm becomes extremely attractive.

  16. Bernstein-type approximations of smooth functions

    Directory of Open Access Journals (Sweden)

    Andrea Pallini

    2007-10-01

    Full Text Available The Bernstein-type approximation for smooth functions is proposed and studied. We propose the Bernstein-type approximation with definitions that directly apply the binomial distribution and the multivariate binomial distribution. The Bernstein-type approximations generalize the corresponding Bernstein polynomials, by considering definitions that depend on a convenient approximation coefficient in linear kernels. In the Bernstein-type approximations, we study the uniform convergence and the degree of approximation. The Bernstein-type estimators of smooth functions of population means are also proposed and studied.

  17. Use of electronic nose and tongue for separation of fruit aromas and non-aroma compounds for quality evaluation

    Science.gov (United States)

    The electronic nose (e-nose) was used to distinguish differences between mango fruit of different harvest maturities, apple fruit to which different coatings were applied, cut apple subjected to heat and ethanol treatments as well as strawberries of different ripeness stages, based on their volatile...

  18. Electronic-nose applications in forensic science and for analysis of volatile biomarkers in the human breath

    Science.gov (United States)

    AD Wilson

    2014-01-01

    The application of electronic-nose (E-nose) technologies in forensic science is a recent new development following a long history of progress in the development of diverse applications in the related biomedical and pharmaceutical fields. Data from forensic analyses must satisfy the needs and requirements of both the scientific and legal communities. The type of data...

  19. 78 FR 63225 - Ear, Nose and Throat Devices Panel of the Medical Devices Advisory Committee; Notice of Meeting

    Science.gov (United States)

    2013-10-23

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF HEALTH AND HUMAN SERVICES Food and Drug Administration Ear, Nose and Throat Devices Panel of the Medical Devices... (FDA). The meeting will be open to the public. Name of Committee: Ear, Nose and Throat Devices Panel...

  20. Flat nose low velocity drop-weight impact response of carbon fibre composites using non-destructive damage detection techniques

    Science.gov (United States)

    Farooq, Umar; Myler, Peter

    2015-03-01

    This work is mainly concerned with the nondestructive post-impact damage evaluation of carbon fibre reinforced laminated composite panels subject to low velocity drop-weight impact by flat and round nose impactors. Quasi-isotropic laminates consisting of eight-, sixteen-, and twenty-four plies were impacted by flat and round nose impactors at different velocity levels. Load-time history data were recorded and plotted to correlate loaddrop as damage level to the impactor nose profiles. Test produced data, non-destructive damage detection techniques: visual, ultrasonic, and eddy- current, and computer simulations were utilised to identify and quantify status of the impact induced damage. To evaluate damage in relatively thick laminates (consisting of 24-Ply), the damage ratios and deflection quantities were correlated to the corresponding impactor nose profiles. Damage induced by the flat nose impactor to thick laminates was compared against the data produced by the round nose impactor. Results show that relatively thin laminates were largely affected by the impactor nose. Reasonable difference was observed in damage caused by flat and round impactor nose profiles to thick laminates impacted at relatively higher velocity impacts. Resultswere compared and validated against simulation produced data.

  1. 3D Stereophotogrammetric assessment of pre- and postoperative volumetric changes in the cleft lip and palate nose.

    NARCIS (Netherlands)

    Loon, B. van; Maal, T.J.J.; Plooij, J.M.; Ingels, K.J.A.O.; Borstlap, W.A.; Kuijpers-Jagtman, A.M.; Spauwen, P.H.M.; Berge, S.J.

    2010-01-01

    In cleft lip and palate patients the shape of the nose invariably changes in three dimensions (3D) due to rhinoplastic surgery. The purpose of this study was to evaluate stereophotogrammetry as a 3D method to document volumetric changes of the nose in patients with a cleft lip (CL) or cleft lip and

  2. Discrimination and characterization of different intensities of goaty flavor in goat milk by means of an electronic nose.

    Science.gov (United States)

    Yang, C J; Ding, W; Ma, L J; Jia, R

    2015-01-01

    An electronic nose based on metal oxide sensors was used to measure goaty flavor in goat milk samples. To study the relationships between electronic nose data, sensory data, and levels of free fatty acids (FFA), multivariate partial least square regression (PLS) was carried out. The electronic nose system evaluation correlated well with sensory evaluation. The coefficients of determination (R(2)) of the PLS models reached 90.0%. The electronic nose, combined with principal component analysis and linear discriminant analysis, can discern among goat milk samples with different goaty flavor intensities. In addition, Fisher discriminant analysis and back-propagation neural network were carried out to evaluate goaty flavor intensity, and the prediction accuracies were 98.2 and 100.0%, respectively. The electronic nose is a potentially useful tool to evaluate goaty flavor intensity in goat milk samples. Copyright © 2015 American Dairy Science Association. Published by Elsevier Inc. All rights reserved.

  3. Are narrow mesons, baryons and dibaryons evidence for multiquark states?

    Energy Technology Data Exchange (ETDEWEB)

    Tatischeff, B.; Yonnet, J. [Paris-11 Univ., 91 - Orsay (France). Inst. de Physique Nucleaire

    2000-07-01

    Several narrow structures have been progressively observed since the last fifteen years, in di-baryonic invariant mass spectra or in missing mass spectra. More recently, narrow structures were observed in baryonic and now in mesonic mass spectra. Since these small peaks appear at fixed masses, independently of the experiment, they are associated with real states. There is no room to explain these states within classical nuclear physics taking into account baryonic and mesonic degrees of freedom. An interpretation is proposed, which associate these narrow structures with two coloured quark clusters. (authors)

  4. Narrowing of Terrace-width Distributions During Growth on Vicinals

    Science.gov (United States)

    Hamouda, Ajmi Bh.; Pimpinelli, A.; Einstein, T. L.

    2009-03-01

    Using kinetic Monte Carlo simulations for a generic minimal SOS model of vicinal surfaces, we compute the terrace-width distributions (TWDs) as a function of incident flux during homoepitaxial growth. We show that the distribution narrows markedly, U.B.P.-Clermont 2 as though there were a flux-dependent repulsion between steps, until the step picture fails at high flux. Using a Fokker-Planck approach, we analyze the evolution and saturation of this narrowing. We compare with a 1D model and with our simulations for narrowing due to an Ehrlich-Schwoebel barrier.

  5. Full Waveform Inversion Using Nonlinearly Smoothed Wavefields

    KAUST Repository

    Li, Y.

    2017-05-26

    The lack of low frequency information in the acquired data makes full waveform inversion (FWI) conditionally converge to the accurate solution. An initial velocity model that results in data with events within a half cycle of their location in the observed data was required to converge. The multiplication of wavefields with slightly different frequencies generates artificial low frequency components. This can be effectively utilized by multiplying the wavefield with itself, which is nonlinear operation, followed by a smoothing operator to extract the artificially produced low frequency information. We construct the objective function using the nonlinearly smoothed wavefields with a global-correlation norm to properly handle the energy imbalance in the nonlinearly smoothed wavefield. Similar to the multi-scale strategy, we progressively reduce the smoothing width applied to the multiplied wavefield to welcome higher resolution. We calculate the gradient of the objective function using the adjoint-state technique, which is similar to the conventional FWI except for the adjoint source. Examples on the Marmousi 2 model demonstrate the feasibility of the proposed FWI method to mitigate the cycle-skipping problem in the case of a lack of low frequency information.

  6. Hydrodynamics of nearly smooth granular gases.

    Science.gov (United States)

    Goldhirsch, I; Noskowicz, S H; Bar-Lev, O

    2005-11-17

    Hydrodynamic equations of motion for a monodisperse collection of nearly smooth homogeneous spheres have been derived from the corresponding Boltzmann equation, using a Chapman-Enskog expansion around the elastic smooth spheres limit. Because in the smooth limit the rotational degrees of freedom are uncoupled from the translational ones, it turns out that the required hydrodynamic fields include (in addition to the standard density, velocity, and translational granular temperature fields) the (infinite) set of number densities, n(s,r, t), corresponding to the continuum of values of the angular velocities. The Chapman-Enskog expansion was carried out to high (up to 10th) order in a Sonine polynomial expansion by using a novel computer-aided method. One of the consequences of these equations is that the asymptotic spin distribution in the homogeneous cooling state for nearly smooth, nearly elastic spheres, is highly non-Maxwellian. The simple sheared flow possesses a highly non-Maxwellian distribution as well. In the case of wall-bounded shear, it is shown that the angular velocity injected at the boundaries has a finite penetration length.

  7. Smooth structures on Eschenburg spaces: numerical computations

    CERN Document Server

    Butler, Leo T

    2009-01-01

    This paper numerically computes the topological and smooth invariants of Eschenburg spaces with small fourth cohomology group, following Kruggel's determination of the Kreck-Stolz invariants of Eschenburg spaces that satisfy condition C. The GNU GMP arbitrary-precision library is utilised.

  8. Quantitative analysis of arm movement smoothness

    Science.gov (United States)

    Szczesna, Agnieszka; Błaszczyszyn, Monika

    2017-07-01

    The paper deals with the problem of motion data quantitative smoothness analysis. We investigated values of movement unit, fluidity and jerk for healthy and paralyzed arm of patients with hemiparesis after stroke. Patients were performing drinking task. To validate the approach, movement of 24 patients were captured using optical motion capture system.

  9. Autophagic regulation of smooth muscle cell biology

    Science.gov (United States)

    Salabei, Joshua K.; Hill, Bradford G.

    2014-01-01

    Autophagy regulates the metabolism, survival, and function of numerous cell types, including those comprising the cardiovascular system. In the vasculature, changes in autophagy have been documented in atherosclerotic and restenotic lesions and in hypertensive vessels. The biology of vascular smooth muscle cells appears particularly sensitive to changes in the autophagic program. Recent evidence indicates that stimuli or stressors evoked during the course of vascular disease can regulate autophagic activity, resulting in modulation of VSMC phenotype and viability. In particular, certain growth factors and cytokines, oxygen tension, and pharmacological drugs have been shown to trigger autophagy in smooth muscle cells. Importantly, each of these stimuli has a redox component, typically associated with changes in the abundance of reactive oxygen, nitrogen, or lipid species. Collective findings support the hypothesis that autophagy plays a critical role in vascular remodeling by regulating smooth muscle cell phenotype transitions and by influencing the cellular response to stress. In this graphical review, we summarize current knowledge on the role of autophagy in the biology of the smooth muscle cell in (patho)physiology. PMID:25544597

  10. Optimality conditions in smooth nonlinear programming

    NARCIS (Netherlands)

    Still, G.; Streng, M.

    1996-01-01

    This survey is concerned with necessary and sufficient optimality conditions for smooth nonlinear programming problems with inequality and equality constraints. These conditions deal with strict local minimizers of order one and two and with isolated minimizers. In most results, no constraint qualif

  11. Topics in particle filtering and smoothing

    NARCIS (Netherlands)

    Saha, Saikat

    2009-01-01

    Particle filtering/smoothing is a relatively new promising class of algorithms to deal with the estimation problems in nonlinear and/or non- Gaussian systems. Currently, this is a very active area of research and there are many issues that are not either properly addressed or are still open. One of

  12. Autonomic Modification of Intestinal Smooth Muscle Contractility

    Science.gov (United States)

    Montgomery, Laura E. A.; Tansey, Etain A.; Johnson, Chris D.; Roe, Sean M.; Quinn, Joe G.

    2016-01-01

    Intestinal smooth muscle contracts rhythmically in the absence of nerve and hormonal stimulation because of the activity of pacemaker cells between and within the muscle layers. This means that the autonomic nervous system modifies rather than initiates intestinal contractions. The practical described here gives students an opportunity to observe…

  13. Recursive Filtering And Smoothing In Robot Dynamics

    Science.gov (United States)

    Rodriguez, Guillermo

    1992-01-01

    Techniques developed originally for electronic systems also useful for multibody mechanical systems. Report summarizes methods developed to solve nonlinear forward-dynamics problem for robot of multiple-link arms connected by joints. Primary objective to show equivalence between recursive methods of dynamical analysis and some filtering and smoothing techniques from state-estimation theory.

  14. Autophagic regulation of smooth muscle cell biology

    Directory of Open Access Journals (Sweden)

    Joshua K. Salabei

    2015-04-01

    Full Text Available Autophagy regulates the metabolism, survival, and function of numerous cell types, including those comprising the cardiovascular system. In the vasculature, changes in autophagy have been documented in atherosclerotic and restenotic lesions and in hypertensive vessels. The biology of vascular smooth muscle cells appears particularly sensitive to changes in the autophagic program. Recent evidence indicates that stimuli or stressors evoked during the course of vascular disease can regulate autophagic activity, resulting in modulation of VSMC phenotype and viability. In particular, certain growth factors and cytokines, oxygen tension, and pharmacological drugs have been shown to trigger autophagy in smooth muscle cells. Importantly, each of these stimuli has a redox component, typically associated with changes in the abundance of reactive oxygen, nitrogen, or lipid species. Collective findings support the hypothesis that autophagy plays a critical role in vascular remodeling by regulating smooth muscle cell phenotype transitions and by influencing the cellular response to stress. In this graphical review, we summarize current knowledge on the role of autophagy in the biology of the smooth muscle cell in (pathophysiology.

  15. Artistic edge and corner enhancing smoothing

    NARCIS (Netherlands)

    Papari, Giuseppe; Petkov, Nicolai; Campisi, Patrizio

    2007-01-01

    Two important visual properties of paintings and painting-like images are the absence of texture details and the increased sharpness of edges as compared to photographic images. Painting-like artistic effects can be achieved from photographic images by filters that smooth out texture details, while

  16. Role of Smooth Muscle in Intestinal Inflammation

    Directory of Open Access Journals (Sweden)

    Stephen M Collins

    1996-01-01

    Full Text Available The notion that smooth muscle function is altered in inflammation is prompted by clinical observations of altered motility in patients with inflammatory bowel disease (IBD. While altered motility may reflect inflammation-induced changes in intrinsic or extrinsic nerves to the gut, changes in gut hormone release and changes in muscle function, recent studies have provided in vitro evidence of altered muscle contractility in muscle resected from patients with ulcerative colitis or Crohn’s disease. In addition, the observation that smooth muscle cells are more numerous and prominent in the strictured bowel of IBD patients compared with controls suggests that inflammation may alter the growth of intestinal smooth muscle. Thus, inflammation is associated with changes in smooth muscle growth and contractility that, in turn, contribute to important symptoms of IBD including diarrhea (from altered motility and pain (via either altered motility or stricture formation. The involvement of smooth muscle in this context may be as an innocent bystander, where cells and products of the inflammatory process induce alterations in muscle contractility and growth. However, it is likely that intestinal muscle cells play a more active role in the inflammatory process via the elaboration of mediators and trophic factors, including cytokines, and via the production of collagen. The concept of muscle cells as active participants in the intestinal inflammatory process is a new concept that is under intense study. This report summarizes current knowledge as it relates to these two aspects of altered muscle function (growth and contractility in the inflamed intestine, and will focus on mechanisms underlying these changes, based on data obtained from animal models of intestinal inflammation.

  17. Electronic-nose technology using sputum samples in diagnosis of patients with tuberculosis

    NARCIS (Netherlands)

    Kolk, A.; Hoelscher, M.; Maboko, L.; Jung, J.; Kuijper, S.; Cauchi, M.; Bessant, C.; van Beers, S.; Dutta, R.; Gibson, T.; Reither, K.

    2010-01-01

    We investigated the potential of two different electronic noses (EN; code named "Rob" and "Walter") to differentiate between sputum headspace samples from tuberculosis (TB) patients and non-TB patients. Only samples from Ziehl-Neelsen stain (ZN)- and Mycobacterium tuberculosis culture-positive (TBPO

  18. Necrosis of nose skin after varicella zoster infection : A case report

    NARCIS (Netherlands)

    Snel, Bart Jorrit; Visconti, Giuseppe; Grabietz, Patrice D.; Werker, Paul M. N.

    Varicella zoster virus (VZV) is the causal agent of varicella (chickenpox) and herpes zoster (shingles). Primary VZV infection is a common childhood disease, but elderly patients and those having a compromised immune system are also at risk. We present the case of progressive necrosis of the nose

  19. INFLUENCE OF NOSE PERTURBATIONS ON BEHAVIORS OF ASYMMETRIC VORTICES OVER SLENDER BODY

    Institute of Scientific and Technical Information of China (English)

    陈学锐; 邓学蓥; 王延奎; 刘沛清; 顾志福

    2002-01-01

    The influence of nose perturbations on the behaviors of asymmetricvortices over a slender body with a three-caliber ogive nose is studied in this paper.The tests of a nose-disturbed slender body with surface pressure measurement wereconducted at a low speed wind tunnel with subcritical Reynolds number of 1×105 atangle of attack α= 50°. The experiment results show that the behaviors and struc-ture of asymmetric vortices over the slender body are mainly controlled by manualperturbation on the nose of body as compared with geometrical minute irregularitieson the test model from the machining tolerances. The effect of the perturbation ax-ial location on asymmetric vortices is the strongest if its location is near the modelapex. There are four sensitive circumferential locations of manual perturbation atwhich bistable vortices over the slender body are switched by the perturbation. Theflowfleld near the reattachment line of lee side is more sensitive to the perturbation,because the saddle point to saddle point topological structure in this reattachmentflowfield is unstable. Various types of perturbation do not change the perturbationeffect on the behaviors of bistable asymmetric vortices.

  20. Use of electronic nose technology to identify cattle experimentally infected with Mycobacterium bovis: A pilot study

    Science.gov (United States)

    Electronic nose technology has historically been utilized for the detection of volatile organic compounds (VOCs) and semi-volatile compounds in air, soil, water, and for quality control in food, beverage and cosmetic industries. Breath analysis has been used experimentally in humans and animals to ...

  1. Chocolate Classification by an Electronic Nose with Pressure Controlled Generated Stimulation

    Science.gov (United States)

    Valdez, Luis F.; Gutiérrez, Juan Manuel

    2016-01-01

    In this work, we will analyze the response of a Metal Oxide Gas Sensor (MOGS) array to a flow controlled stimulus generated in a pressure controlled canister produced by a homemade olfactometer to build an E-nose. The built E-nose is capable of chocolate identification between the 26 analyzed chocolate bar samples and four features recognition (chocolate type, extra ingredient, sweetener and expiration date status). The data analysis tools used were Principal Components Analysis (PCA) and Artificial Neural Networks (ANNs). The chocolate identification E-nose average classification rate was of 81.3% with 0.99 accuracy (Acc), 0.86 precision (Prc), 0.84 sensitivity (Sen) and 0.99 specificity (Spe) for test. The chocolate feature recognition E-nose gives a classification rate of 85.36% with 0.96 Acc, 0.86 Prc, 0.85 Sen and 0.96 Spe. In addition, a preliminary sample aging analysis was made. The results prove the pressure controlled generated stimulus is reliable for this type of studies. PMID:27775628

  2. Application and Uses of Electronic Noses for Clinical Diagnosis on Urine Samples: A Review

    Science.gov (United States)

    Capelli, Laura; Taverna, Gianluigi; Bellini, Alessia; Eusebio, Lidia; Buffi, Niccolò; Lazzeri, Massimo; Guazzoni, Giorgio; Bozzini, Giorgio; Seveso, Mauro; Mandressi, Alberto; Tidu, Lorenzo; Grizzi, Fabio; Sardella, Paolo; Latorre, Giuseppe; Hurle, Rodolfo; Lughezzani, Giovanni; Casale, Paolo; Meregali, Sara; Sironi, Selena

    2016-01-01

    The electronic nose is able to provide useful information through the analysis of the volatile organic compounds in body fluids, such as exhaled breath, urine and blood. This paper focuses on the review of electronic nose studies and applications in the specific field of medical diagnostics based on the analysis of the gaseous headspace of human urine, in order to provide a broad overview of the state of the art and thus enhance future developments in this field. The research in this field is rather recent and still in progress, and there are several aspects that need to be investigated more into depth, not only to develop and improve specific electronic noses for different diseases, but also with the aim to discover and analyse the connections between specific diseases and the body fluids odour. Further research is needed to improve the results obtained up to now; the development of new sensors and data processing methods should lead to greater diagnostic accuracy thus making the electronic nose an effective tool for early detection of different kinds of diseases, ranging from infections to tumours or exposure to toxic agents. PMID:27754437

  3. Papular acne scars of the nose and chin: An under-recognised variant of acne scarring

    Directory of Open Access Journals (Sweden)

    Faisal R Ali

    2016-01-01

    Full Text Available Background: Scarring following acne vulgaris is common and can be of profound psychosocial consequence. Aims and Objectives: We have clinically noted a variant of acne scarring, overlooked by previous categorisation schemes, which we have denominated as papular acne scars of the nose and chin. We sought to characterise these novel entities further. Materials and Methods: Initially, we identified 14 patients with papular acne scars of the nose and chin in a cosmetic dermatology clinic, of whom two were female and rest were male. We then prospectively evaluated 100 consecutive patients attending our tertiary referral acne isotretinoin clinic and 49 patients attending a general dermatology clinic. Results: Amongst 149 patients, from a general dermatology and tertiary acne clinic, soft papular scars were noted in four patients, distributed on the nose and chin. Three of the four patients were male, three patients had additional acne scars and the median age was 23.5. Conclusions: We have identified 18 patients with papular acne scars of the nose and chin and propose that this new category should be added to acne scarring classification schemes. Future work should be directed at corroborating the epidemiology of such lesions and describing effective treatment modalities.

  4. Acetic Acid Detection Threshold in Synthetic Wine Samples of a Portable Electronic Nose

    Directory of Open Access Journals (Sweden)

    Miguel Macías Macías

    2012-12-01

    Full Text Available Wine quality is related to its intrinsic visual, taste, or aroma characteristics and is reflected in the price paid for that wine. One of the most important wine faults is the excessive concentration of acetic acid which can cause a wine to take on vinegar aromas and reduce its varietal character. Thereby it is very important for the wine industry to have methods, like electronic noses, for real-time monitoring the excessive concentration of acetic acid in wines. However, aroma characterization of alcoholic beverages with sensor array electronic noses is a difficult challenge due to the masking effect of ethanol. In this work, in order to detect the presence of acetic acid in synthetic wine samples (aqueous ethanol solution at 10% v/v we use a detection unit which consists of a commercial electronic nose and a HSS32 auto sampler, in combination with a neural network classifier (MLP. To find the characteristic vector representative of the sample that we want to classify, first we select the sensors, and the section of the sensors response curves, where the probability of detecting the presence of acetic acid will be higher, and then we apply Principal Component Analysis (PCA such that each sensor response curve is represented by the coefficients of its first principal components. Results show that the PEN3 electronic nose is able to detect and discriminate wine samples doped with acetic acid in concentrations equal or greater than 2 g/L.

  5. Improving Short Term Instability for Quantitative Analyses with Portable Electronic Noses

    Directory of Open Access Journals (Sweden)

    Miguel Macías Macías

    2014-06-01

    Full Text Available One of the main problems when working with electronic noses is the lack of reproducibility or repeatability of the sensor response, so that, if this problem is not properly considered, electronic noses can be useless, especially for quantitative analyses. On the other hand, irreproducibility is increased with portable and low cost electronic noses where laboratory equipment like gas zero generators cannot be used. In this work, we study the reproducibility of two portable electronic noses, the PEN3 (commercial and CAPINose (a proprietary design by using synthetic wine samples. We show that in both cases short term instability associated to the sensors’ response to the same sample and under the same conditions represents a major problem and we propose an internal normalization technique that, in both cases, reduces the variability of the sensors’ response. Finally, we show that the normalization proposed seems to be more effective in the CAPINose case, reducing, for example, the variability associated to the TGS2602 sensor from 12.19% to 2.2%.

  6. Data Fusion of Electronic Nose and Electronic Tongue for Detection of Mixed Edible-Oil

    Directory of Open Access Journals (Sweden)

    Hong Men

    2014-01-01

    Full Text Available For the problem of the waste of the edible-oil in the food processing, on the premise of food security, they often need to add new edible-oil to the old frying oil which had been used in food processing to control the cost of the production. Due to the fact that the different additive proportion of the oil has different material and different volatile gases, we use fusion technology based on the electronic nose and electronic tongue to detect the blending ratio of the old frying oil and the new edible-oil in this paper. Principal component analysis (PCA is used to distinguish the different proportion of the old frying oil and new edible-oil; on the other hand we use partial least squares (PLS to predict the blending ratio of the old frying oil and new edible-oil. Two conclusions were proposed: data fusion of electronic nose and electronic tongue can be used to detect the blending ratio of the old frying oil and new edible-oil; in contrast to single used electronic nose or single used electronic tongue, the detection effect has increased by using data fusion of electronic nose and electronic tongue.

  7. Monitoring of biological odour filtration in closed environments with olfactometry and an electronic nose

    NARCIS (Netherlands)

    Willers, H.C.; Gijsel, de P.; Ogink, N.W.M.; Amico, D' A.; Martinelli, E.; Natale, Di C.; Ras, van N.; Waarde, van der J.

    2004-01-01

    Air treatment with a compact biological membrane filter, and air quality monitoring with an electronic nose were tested in the laboratory on air from a cage containing six mice. Additional analyses of air to and from the filter were performed using olfactometry and ammonia and hydrogen sulphide gas

  8. Pet-keeping in early childhood and airway, nose and skin symptoms later in life

    DEFF Research Database (Denmark)

    Bornehag, C.; Sundell, Jan; Hagerhed, L.

    2003-01-01

    Background: It is discussed whether exposure to pets during childhood is a risk or a protective factor for sensitization and allergic symptoms. The aim of this study was to investigate the association between pet-keeping at time of birth and allergic symptoms in airways, nose and skin among young...

  9. Data-driven modeling of nano-nose gas sensor arrays

    DEFF Research Database (Denmark)

    Alstrøm, Tommy Sonne; Larsen, Jan; Nielsen, Claus Højgård

    2010-01-01

    We present a data-driven approach to classification of Quartz Crystal Microbalance (QCM) sensor data. The sensor is a nano-nose gas sensor that detects concentrations of analytes down to ppm levels using plasma polymorized coatings. Each sensor experiment takes approximately one hour hence the nu......-of-the-art machine learning methods and the Bayesian learning paradigm....

  10. Data–driven modeling of nano-nose gas sensor arrays

    DEFF Research Database (Denmark)

    Alstrøm, Tommy Sonne; Larsen, Jan; Nielsen, Claus Højgård

    2010-01-01

    We present a data-driven approach to classification of Quartz Crystal Microbalance (QCM) sensor data. The sensor is a nano-nose gas sensor that detects concentrations of analytes down to ppm levels using plasma polymorized coatings. Each sensor experiment takes approximately one hour hence the nu......-of-the-art machine learning methods and the Bayesian learning paradigm....

  11. An electronic nose for amine detection based on polymer/SWNT-COOH nanocomposite.

    Science.gov (United States)

    Lorwongtragooll, Panida; Wisitsoraat, Anurat; Kerdcharoen, Teerakiat

    2011-12-01

    An electronic nose (e-nose) system based on polymer/carboxylic-functionalized single-walled carbon nanotubes (SWNT-COOH) was developed for sensing various volatile amines. The SWNT-COOH dispersed in the matrix of different polymers; namely, polyvinyl chloride (PVC), cumene terminated polystyrene-co-maleic anhydride (cumene-PSMA), poly(styrenecomaleic acid) partial isobutyl/methyl mixed ester (PSE), and polyvinylpyrrolidon (PVP), were deposited on interdigitated gold electrodes to make the gas sensors. The response of these sensors to volatile amines was studied by both static and dynamic flow measurements. It was found that all sensors exhibited behaviors corresponding to Plateau-Bretano-Stevens law (R2 = 0.81 to 0.99) as the response to volatile amines. Real-world application was demonstrated by applying this e-nose to monitor the odor of sun-dried snakeskin gourami that was pre-processed by salting-preservation. This electronic nose can discriminate sun-dried fish odors with different stored days using a simple pattern recognition based on the principal component analysis (PCA).

  12. Chocolate Classification by an Electronic Nose with Pressure Controlled Generated Stimulation.

    Science.gov (United States)

    Valdez, Luis F; Gutiérrez, Juan Manuel

    2016-10-20

    In this work, we will analyze the response of a Metal Oxide Gas Sensor (MOGS) array to a flow controlled stimulus generated in a pressure controlled canister produced by a homemade olfactometer to build an E-nose. The built E-nose is capable of chocolate identification between the 26 analyzed chocolate bar samples and four features recognition (chocolate type, extra ingredient, sweetener and expiration date status). The data analysis tools used were Principal Components Analysis (PCA) and Artificial Neural Networks (ANNs). The chocolate identification E-nose average classification rate was of 81.3% with 0.99 accuracy (Acc), 0.86 precision (Prc), 0.84 sensitivity (Sen) and 0.99 specificity (Spe) for test. The chocolate feature recognition E-nose gives a classification rate of 85.36% with 0.96 Acc, 0.86 Prc, 0.85 Sen and 0.96 Spe. In addition, a preliminary sample aging analysis was made. The results prove the pressure controlled generated stimulus is reliable for this type of studies.

  13. Development of an Electronic Nose Sensing Platform for Undergraduate Education in Nanotechnology

    Science.gov (United States)

    Russo, Daniel V.; Burek, Michael J.; Iutzi, Ryan M.; Mracek, James A.; Hesjedal, Thorsten

    2011-01-01

    The teaching of the different aspects of a sensor system, with a focus on the involved nanotechnology, is a challenging, yet important task. We present the development of an electronic nose system that utilizes a nanoscale amperometric sensing mechanism for gas mixtures. The fabrication of the system makes use of a basic microfabrication facility,…

  14. Data-driven modeling of nano-nose gas sensor arrays

    DEFF Research Database (Denmark)

    Alstrøm, Tommy Sonne; Larsen, Jan; Nielsen, Claus Højgård

    2010-01-01

    We present a data-driven approach to classification of Quartz Crystal Microbalance (QCM) sensor data. The sensor is a nano-nose gas sensor that detects concentrations of analytes down to ppm levels using plasma polymorized coatings. Each sensor experiment takes approximately one hour hence...

  15. Necrosis of nose skin after varicella zoster infection : A case report

    NARCIS (Netherlands)

    Snel, Bart Jorrit; Visconti, Giuseppe; Grabietz, Patrice D.; Werker, Paul M. N.

    2010-01-01

    Varicella zoster virus (VZV) is the causal agent of varicella (chickenpox) and herpes zoster (shingles). Primary VZV infection is a common childhood disease, but elderly patients and those having a compromised immune system are also at risk. We present the case of progressive necrosis of the nose sk

  16. Increased number of ear-nose-throat malpractice complaints in Denmark

    DEFF Research Database (Denmark)

    Nikoghosyan-Bossen, Gohar; Hauberg, Agnes; Homøe, Preben

    2012-01-01

    Danish ear, nose and throat (ENT) physicians have little knowledge of the type of decisions made at the Danish National Board of Patients' Complaints (NBPC). The aim of this study was to analyze and describe the epidemiology of ENT malpractice complaints by showing their distribution and volume i...

  17. Systematic analysis of ear-nose-throat malpractice complaints may be beneficial for patient safety

    DEFF Research Database (Denmark)

    Nikoghosyan-Bossen, Gohar; Hauberg, Agnes; Homøe, Preben

    2012-01-01

    The analysis of malpractice complaints can provide valuable information on patient safety. This study offers a detailed examination of the backgrounds concerning reasons and outcomes of ear, nose and throat (ENT) malpractice complaints handled by the National Board of Patients' Complaints (NBPC),...

  18. Progress in bionic information processing techniques for an electronic nose based on olfactory models

    Institute of Scientific and Technical Information of China (English)

    LI Guang; FU Jun; ZHANG Jia; ZHENG JunBao

    2009-01-01

    As a novel bionic analytical technique, an electronic nose, inspired by the mechanism of the biological olfactory system and integrated with modern sensing technology, electronic technology and pattern recognition technology, has been widely used in many areas. Moreover, recent basic research findings in biological olfaction combined with computational neuroscience promote its development both in methodology and application. In this review, the basic information processing principle of biological olfaction and artificial olfaction are summarized and compared, and four olfactory models and their applications to electronic noses are presented. Finally, a chaotic olfactory neural network is detailed and the utilization of several biologically oriented learning rules and its spatiotemporal dynamic prop-ties for electronic noses are discussed. The integration of various phenomena and their mechanisms for biological olfaction into an electronic nose context for information processing will not only make them more bionic, but also perform better than conventional methods. However, many problems still remain, which should be solved by further cooperation between theorists and engineers.

  19. Mechanistic identification of cutting force coefficients in bull-nose milling process

    Institute of Scientific and Technical Information of China (English)

    Gao Ge; Wu Baohai; Zhang Dinghua; Luo Ming

    2013-01-01

    An improved method to determine cutting force coefficients for bull-nose cutters is proposed based on the semi-mechanistic cutting force model.Due to variations of cutting speed along the tool axis in bull-nose milling,they affect coefficients significantly and may bring remarkable discrepancies in the prediction of cutting forces.Firstly,the bull-nose cutter is regarded as a finite number of axial discs piled up along the tool axis,and the rigid cutting force model is exerted.Then through discretization along cutting edges,the cutting force related to each element is recalculated,which equals to differential force value between the current and previous elements.In addition,coefficient identification adopts the cubic polynomial fitting method with the slice elevation as its horizontal axis.By calculating relations of cutting speed and cutting depth,the influences of speed variations on cutting force can be derived.Thereby,several tests are conducted to calibrate the coefficients using the improved method,which are applied to later force predictions.Eventually,experimental evaluations are discussed to verify the effectiveness.Compared to the conventional method,the results are more accurate and show satisfactory consistency with the simulations.For further applications,the method is instructive to predict the cutting forces in bull-nose milling with lead or tilt angles and can be extended to the selection of cutting parameters.

  20. Chocolate Classification by an Electronic Nose with Pressure Controlled Generated Stimulation

    Directory of Open Access Journals (Sweden)

    Luis F. Valdez

    2016-10-01

    Full Text Available In this work, we will analyze the response of a Metal Oxide Gas Sensor (MOGS array to a flow controlled stimulus generated in a pressure controlled canister produced by a homemade olfactometer to build an E-nose. The built E-nose is capable of chocolate identification between the 26 analyzed chocolate bar samples and four features recognition (chocolate type, extra ingredient, sweetener and expiration date status. The data analysis tools used were Principal Components Analysis (PCA and Artificial Neural Networks (ANNs. The chocolate identification E-nose average classification rate was of 81.3% with 0.99 accuracy (Acc, 0.86 precision (Prc, 0.84 sensitivity (Sen and 0.99 specificity (Spe for test. The chocolate feature recognition E-nose gives a classification rate of 85.36% with 0.96 Acc, 0.86 Prc, 0.85 Sen and 0.96 Spe. In addition, a preliminary sample aging analysis was made. The results prove the pressure controlled generated stimulus is reliable for this type of studies.

  1. Electronic noses and tongues: Applications for the food and pharmaceutical industries

    Science.gov (United States)

    The electronic nose (enose) is designed to crudely mimic the human brain in that most contain sensors that non-selectively interact with odor molecules to produce some sort of signal that is then sent to a computer that uses multivariate statistics to determine patterns in the data. This pattern rec...

  2. Impact perforation of polymer–metal laminates: Projectile nose shape sensitivity

    National Research Council Canada - National Science Library

    Mohagheghian, I; McShane, G.J; Stronge, W.J

    2016-01-01

    ... into the influence of a polymer coating on the resistance to projectile perforation of a target plate remain relatively limited. It has been shown by Mohagheghian et al., in press that a polymer layer can significantly enhance the impact perforation resistance of a thin metallic plate struck by a blunt-nosed projectile. When placed on the impacted (proximal) fa...

  3. Unilateral cleft lip and palate: Simultaneous early repair of the nose, anterior palate and lip

    Science.gov (United States)

    Laberge, Louise Caouette

    2007-01-01

    Unilateral cleft lip and palate is a defect involving the lip, nose and maxilla. These structures are inter-related, and simultaneous early correction of all the aspects of the defect is necessary to obtain a satisfactory result that will be maintained with growth. The surgical technique combining various procedures is presented and compared with previously published reports. PMID:19554125

  4. The New Star, the New Nose: Tycho Brahe's Nasal Prosthesis. A Nosepiece for Peter

    DEFF Research Database (Denmark)

    Østermark-Johansen, Lene

    2017-01-01

    and contextualizes it within cutting-edge sixteenth-century rhinoplasty. The shiny nose, given fetish status by Freud in 1927, became an object of ridicule in seventeenth-century satire, but only Brahe knew how to link the microcosmic and the macrocosmic, the heavenly and the earthly stars....

  5. Oriental Nose Occidentalization and Perinasal Shaping by Augmentation of the Underdeveloped Anterior Nasal Spine

    Directory of Open Access Journals (Sweden)

    Yohei Tanaka, MD, PhD

    2014-08-01

    Conclusions: Objective assessments showed significant effects of this treatment, with good patient satisfaction and minimal levels of discomfort and side effects. Together these results demonstrate that this treatment is safe and effective for Oriental nose occidentalization and perinasal shaping and is also useful for predicting rhinoplasty results.

  6. Detecting Cannabis Use on the Human Skin Surface via an Electronic Nose System

    Directory of Open Access Journals (Sweden)

    Andreas Voss

    2014-07-01

    Full Text Available The most commonly used drug testing methods are based on the analysis of hair and urine using gas chromatography-mass spectrometry, liquid chromatography-mass spectrometry or immunoassay screening. These methods are time-consuming and partly expensive. One alternative method could be the application of an “electronic nose” (eNose. We have developed an eNose to detect directly on the human skin surface metabolic changes in the human body odor caused by cannabis consumption. Twenty cannabis-smoking and 20 tobacco-smoking volunteers were enrolled in this study. For the sensor signal data processing, two different methods were applied: Principle component analysis (PCA with discriminant analysis, and the method of pattern recognition with subsequent support vector machines (SVM processing. The PCA analysis achieved a correct classification of 70%, whereas the SVM obtained an accuracy of 92.5% (sensitivity 95%, specificity 90% between cannabis-consuming volunteers and tobacco-smoking subjects. This study shows evidence that a low-cost, portable and fast-working eNose system could be useful for health protection, security agencies and for forensic investigations. The ability to analyze human body odor with an eNose opens up a wide field for diagnosing other drugs and also various diseases.

  7. Evaluation of an autoclave resistant anatomic nose model for the testing of nasal swabs.

    Science.gov (United States)

    Bartolitius, Lennart; Frickmann, Hagen; Warnke, Philipp; Ottl, Peter; Podbielski, Andreas

    2014-09-01

    A nose model that allows for the comparison of different modes of sample acquisition as well as of nasal swab systems concerning their suitability to detect defined quantities of intranasal microorganisms, and further for training procedures of medical staff, was evaluated. Based on an imprint of a human nose, a model made of a silicone elastomer was formed. Autoclave stability was assessed. Using an inoculation suspension containing Staphylococcus aureus and Staphylococcus epidermidis, the model was compared with standardized glass plate inoculations. Effects of inoculation time, mode of sampling, and sample storage time were assessed. The model was stable to 20 autoclaving cycles. There were no differences regarding the optimum coverage from the nose and from glass plates. Optimum sampling time was 1 h after inoculation. Storage time after sampling was of minor relevance for the recovery. Rotating the swab around its own axis while circling the nasal cavity resulted in best sampling results. The suitability of the assessed nose model for the comparison of sampling strategies and systems was confirmed. Without disadvantages in comparison with sampling from standardized glass plates, the model allows for the assessment of a correct sampling technique due to its anatomically correct shape.

  8. Integrating narrow therapeutic index drug formulations in transplantation

    NARCIS (Netherlands)

    A. Johnston (Andrew); L. Schick (Liz); T. van Gelder (Teun)

    2012-01-01

    textabstractThere is considerable debate regarding generic drug substitution in solid organ transplant recipients, and various European transplant associations and societies have expressed caution about the potential adverse consequences from uncontrolled switching between the different narrow

  9. Single Frequency Narrow Linewidth 2 Micron Laser Project

    Data.gov (United States)

    National Aeronautics and Space Administration — NASA needs narrow linewidth lasers in the 1.5 or 2 micron wavelength regime for coherent Lidar applications. The laser should be tunable by several nm and frequency...

  10. A Compact Narrow-Band Tunable Optical Transversal Filter

    Institute of Scientific and Technical Information of China (English)

    Zhigang Wu; Katsuyuki Utaka

    2003-01-01

    We present a compact narrow-band tunable optical transversal filter with phase-variable taps. A transmission bandwidth of the comb filter is less than 0.2nm and can be continuously tuned in the entire FSR.

  11. Comment on the narrow structure reported by Amaryan et al

    CERN Document Server

    Anghinolfi, M; Baltzell, N A; Battaglieri, M; Bedlinskiy, I; Bellis, M; Biselli, A S; Bookwalter, C; Boiarinov, S; Bosted, P; Burkert, V D; Carman, D S; Celentano, A; Chandavar, S; Cole, P L; Crede, V; De Vita, R; De Sanctis, E; Dey, B; Dickson, R; Doughty, D; Dugger, M; Dupre, R; Egiyan, H; Alaoui, A El; Fassi, L El; Elouadrhiri, L; Eugenio, P; Fedotov, G; Gabrielyan, M Y; Garcon, M; Gilfoyle, G P; Giovanetti, K L; Girod, F X; Goetz, J T; Golovatch, E; Guidal, M; Guo, L; Hafidi, K; Hakobyan, H; Heddle, D; Hicks, K; Holtrop, M; Ireland, D G; Ishkhanov, B S; Isupov, E L; Jo, H S; Joo, K; Khetarpal, P; Kim, A; Kim, W; Kubarovsky, V; Kuleshov, S V; Lu, H Y; MacGregor, L J D; Markov, N; McCracken, M E; McKinnon, B; Mestayer, M D; Meyer, C A; Mirazita, M; Mokeev, V; Moriya, K; Morrison, B; Ni, A; Niccolai, S; Niculescu, G; Niculescu, I; Osipenko, M; Ostrovidov, A I; Park, K; Park, S; Pereira, S Anefalos; Pisano, S; Pogorelko, O; Pozdniakov, S; Price, J W; Ricco, G; Ripani, M; Ritchie, B G; Rossi, P; Schott, D; Schumacher, R A; Seder, E; Sharabian, Y G; Smith, E S; Sober, D I; Stepanyan, S S; Stoler, P; Tang, W; Ungaro, M; Vernarsky, B; Vineyard, M F; Weygand, D P; Wood, M H; Zachariou, N; Zhao, B

    2012-01-01

    The CLAS Collaboration provides a comment on the physics interpretation of the results presented in a paper published by M. Amaryan et al. regarding the possible observation of a narrow structure in the mass spectrum of a photoproduction experiment.

  12. Novel bioequivalence approach for narrow therapeutic index drugs.

    Science.gov (United States)

    Yu, L X; Jiang, W; Zhang, X; Lionberger, R; Makhlouf, F; Schuirmann, D J; Muldowney, L; Chen, M-L; Davit, B; Conner, D; Woodcock, J

    2015-03-01

    Narrow therapeutic index drugs are defined as those drugs where small differences in dose or blood concentration may lead to serious therapeutic failures and/or adverse drug reactions that are life-threatening or result in persistent or significant disability or incapacity. The US Food and Drug Administration proposes that the bioequivalence of narrow therapeutic index drugs be determined using a scaling approach with a four-way, fully replicated, crossover design study in healthy subjects that permits the simultaneous equivalence comparison of the mean and within-subject variability of the test and reference products. The proposed bioequivalence limits for narrow therapeutic index drugs of 90.00%-111.11% would be scaled based on the within-subject variability of the reference product. The proposed study design and data analysis should provide greater assurance of therapeutic equivalence of narrow therapeutic index drug products.

  13. Study on critical heat flux in narrow rectangular channel with repeated-rib roughness. 1. Experimental facility and preliminary experiments

    Energy Technology Data Exchange (ETDEWEB)

    Kinoshita, Hidetaka; Terada, Atsuhiko; Kaminaga, Masanori; Hino, Ryutaro [Japan Atomic Energy Research Inst., Tokai, Ibaraki (Japan). Tokai Research Establishment

    2001-10-01

    In the design of a spallation target system, the water cooling system, for example a proton beam window and a safety hull, is used with narrow channels, in order to remove high heat flux and prevent lowering of system performance by absorption of neutron. And in narrow channel, heat transfer enhancement using 2-D rib is considered for reduction the cost of cooling component and decrease inventory of water in the cooling system, that is, decrease of the amount of irradiated water. But few studies on CHF with rib have been carried out. Experimental and analytical studies with rib-roughened test section, in 10:1 ratio of pitch to height, are being carried out in order to clarify the CHF in rib-roughened channel. This paper presents the review of previous researches on heat transfer in channel with rib roughness, overview of the test facility and the preliminary experimental and analytical results. As a result, wall friction factors were about 3 times as large as that of smooth channel, and heat transfer coefficients are about 2 times as large as that of smooth channel. The obtained CHF was as same as previous mechanistic model by Sudo. (author)

  14. STUDY OF HYDRODYNAMIC FORCES OF SHIPS IN NARROW WATERWAY

    Institute of Scientific and Technical Information of China (English)

    Zhang Xie-dong; Wu Xiu-heng

    2003-01-01

    The collision of ships in narrow waterway may occur for a variety of reasons. The hydrodynamic forces between two ships change the maneuvering characteristics of ships greatly. So based on the boundary element method, this paper proposes a calculation method for hydrodynamic interaction forces between ships under meeting and passing conditions in narrow waterway. The results from this method are compared with the existing results obtained from other theoretical approaches, and they are in good agreement.

  15. E-Nose and e-Tongue combination for improved recognition of fruit juice samples.

    Science.gov (United States)

    Haddi, Z; Mabrouk, S; Bougrini, M; Tahri, K; Sghaier, K; Barhoumi, H; El Bari, N; Maaref, A; Jaffrezic-Renault, N; Bouchikhi, B

    2014-05-01

    There are many important challenges related to food security analysis by application of chemical and electrochemical sensors. One critical parameter is the development of reliable tools, capable of performing an overall sensory analysis. In these systems, as much information as possible is required in relation to smell, taste and colour. Here, we investigated the possibility of using a multisensor data fusion approach, which combines an e-Nose and an e-Tongue, adept in generating combined aroma and taste profiles. In order to shed light on this concept, classification of various Tunisian fruit juices using a low-level of abstraction data fusion technique was attempted. Five tin oxide-based Taguchi Gas Sensors were applied in the e-Nose instrument and the e-Tongue was designed using six potentiometric sensors. Four different commercial brands along with eleven fruit juice varieties were characterised using the e-Nose and the e-Tongue as individual techniques, followed by a combination of the two together. Applying Principal Component Analysis (PCA) separately on the respective e-Nose and e-Tongue data, only few distinct groups were discriminated. However, by employing the low-level of abstraction data fusion technique, very impressive findings were achieved. The Fuzzy ARTMAP neural network reached a 100% success rate in the recognition of the eleven-fruit juices. Therefore, data fusion approach can successfully merge individual data from multiple origins to draw the right conclusions that are more fruitful when compared to the original single data. Hence, this work has demonstrated that data fusion strategy used to combine e-Nose and e-Tongue signals led to a system of complementary and comprehensive information of the fruit juices which outperformed the performance of each instrument when applied separately.

  16. Pressure effects on the nose by an in-flight oxygen mask during simulated flight conditions.

    Science.gov (United States)

    Schreinemakers, J Rieneke C; Boer, C; van Amerongen, P C G M; Kon, M

    2016-12-01

    Dutch F-16 fighter pilots experience oxygen mask inflicted nasal trauma, including discomfort, pain, skin abrasions, bruises and bone remodelling. Pressure and shear forces on the nose might contribute to causing these adverse effects. In this study, it was evaluated how flight conditions affected the exerted pressure, and whether shear forces were present. The pressure exerted by the oxygen mask was measured in 20 volunteers by placing pressure sensors on the nose and chin underneath the mask. In the human centrifuge, the effects on the exerted pressure during different flight conditions were evaluated (+3Gz, +6Gz, +9Gz, protocolised head movements, mounted visor or night vision goggles, NVG). The runs were recorded to evaluate if the mask's position changed during the run, which would confirm the presence of shear forces. Head movements increased the median pressure on the nose by 50 mm Hg and on the chin by 37 mm Hg. NVG, a visor and accelerative forces also increased the median pressure on the nose. Pressure drops on the nose were also observed, during mounted NVG (-63 mm Hg). The recordings showed the mask slid downwards, especially during the acceleration phase of the centrifuge run, signifying the presence of shear forces. The exerted pressure by the oxygen mask changes during different flight conditions. Exposure to changing pressures and to shear forces probably contributes to mask-inflicted nasal trauma. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/.

  17. Hispanic rhinoplasty in the United States, with emphasis on the Mexican American nose.

    Science.gov (United States)

    Daniel, Rollin K

    2003-07-01

    Because an increasing number of Hispanic patients are seeking nasal surgical treatment, a critical analysis of 25 consecutive Hispanic rhinoplasties was performed. After a review of the patient data and preoperative photographs, a new classification was developed, based on the type of deformity rather than geographical origins (as previously used). A treatment paradigm is offered for each type of deformity. Type I involves a high radix, a high dorsum, and a nearly normal tip and is often referred to as a Castilian nose. Treatment consists of a closed functional reduction rhinoplasty, with dorsal reduction and minor tip changes. Type II involves a low radix, a normal dorsum, and a dependent tip and is a new designation. Treatment consists of a finesse rhinoplasty with a radix graft, minimal dorsal changes, use of a columellar strut for support, and open tip suturing. Type III involves a broad base, thick skin, and a wide tip deformity, with its worst expression in the mestizo nose. Treatment consists of a balanced rhinoplasty with minimal dorsal alteration but maximal lobular reduction and an open-structure tip graft. The following conclusions with respect to Hispanic rhinoplasty in the United States are important: (1) an enormous anatomical diversity of deformities is present, in contrast to Asian and black noses; (2) three distinct types of deformities have been identified, each of which requires a different surgical approach; (3) a wide variety of surgical techniques are necessary, in contrast to other ethnic noses; (4) conservative dorsal reduction is essential for type II and III noses; and (5) limitations imposed by the skin envelope are far less than presupposed, and the results are better than generally recognized. As the Hispanic population grows and becomes more prosperous, plastic surgeons in the United States can expect to encounter an increasing number of Hispanic patients requesting rhinoplasty.

  18. Quality Detection of Litchi Stored in Different Environments Using an Electronic Nose

    Directory of Open Access Journals (Sweden)

    Sai Xu

    2016-06-01

    Full Text Available The purpose of this paper was to explore the utility of an electronic nose to detect the quality of litchi fruit stored in different environments. In this study, a PEN3 electronic nose was adopted to test the storage time and hardness of litchi that were stored in three different types of environment (room temperature, refrigerator and controlled-atmosphere. After acquiring data about the hardness of the sample and from the electronic nose, linear discriminant analysis (LDA, canonical correlation analysis (CCA, BP neural network (BPNN and BP neural network-partial least squares regression (BPNN-PLSR, were employed for data processing. The experimental results showed that the hardness of litchi fruits stored in all three environments decreased during storage. The litchi stored at room temperature had the fastest rate of decrease in hardness, followed by those stored in a refrigerator environment and under a controlled-atmosphere. LDA has a poor ability to classify the storage time of the three environments in which litchi was stored. BPNN can effectively recognize the storage time of litchi stored in a refrigerator and a controlled-atmosphere environment. However, the BPNN classification of the effect of room temperature storage on litchi was poor. CCA results show a significant correlation between electronic nose data and hardness data under the room temperature, and the correlation is more obvious for those under the refrigerator environment and controlled-atmosphere environment. The BPNN-PLSR can effectively predict the hardness of litchi under refrigerator storage conditions and a controlled-atmosphere environment. However, the BPNN-PLSR prediction of the effect of room temperature storage on litchi and global environment storage on litchi were poor. Thus, this experiment proved that an electronic nose can detect the quality of litchi under refrigeratored storage and a controlled-atmosphere environment. These results provide a useful

  19. Quality Detection of Litchi Stored in Different Environments Using an Electronic Nose

    Science.gov (United States)

    Xu, Sai; Lü, Enli; Lu, Huazhong; Zhou, Zhiyan; Wang, Yu; Yang, Jing; Wang, Yajuan

    2016-01-01

    The purpose of this paper was to explore the utility of an electronic nose to detect the quality of litchi fruit stored in different environments. In this study, a PEN3 electronic nose was adopted to test the storage time and hardness of litchi that were stored in three different types of environment (room temperature, refrigerator and controlled-atmosphere). After acquiring data about the hardness of the sample and from the electronic nose, linear discriminant analysis (LDA), canonical correlation analysis (CCA), BP neural network (BPNN) and BP neural network-partial least squares regression (BPNN-PLSR), were employed for data processing. The experimental results showed that the hardness of litchi fruits stored in all three environments decreased during storage. The litchi stored at room temperature had the fastest rate of decrease in hardness, followed by those stored in a refrigerator environment and under a controlled-atmosphere. LDA has a poor ability to classify the storage time of the three environments in which litchi was stored. BPNN can effectively recognize the storage time of litchi stored in a refrigerator and a controlled-atmosphere environment. However, the BPNN classification of the effect of room temperature storage on litchi was poor. CCA results show a significant correlation between electronic nose data and hardness data under the room temperature, and the correlation is more obvious for those under the refrigerator environment and controlled-atmosphere environment. The BPNN-PLSR can effectively predict the hardness of litchi under refrigerator storage conditions and a controlled-atmosphere environment. However, the BPNN-PLSR prediction of the effect of room temperature storage on litchi and global environment storage on litchi were poor. Thus, this experiment proved that an electronic nose can detect the quality of litchi under refrigeratored storage and a controlled-atmosphere environment. These results provide a useful reference for future

  20. A Generalized Eigensolver based on Smoothed Aggregation (GES-SA) for Initializing Smoothed Aggregation Multigrid (SA)

    Energy Technology Data Exchange (ETDEWEB)

    Brezina, M; Manteuffel, T; McCormick, S; Ruge, J; Sanders, G; Vassilevski, P S

    2007-05-31

    Consider the linear system Ax = b, where A is a large, sparse, real, symmetric, and positive definite matrix and b is a known vector. Solving this system for unknown vector x using a smoothed aggregation multigrid (SA) algorithm requires a characterization of the algebraically smooth error, meaning error that is poorly attenuated by the algorithm's relaxation process. For relaxation processes that are typically used in practice, algebraically smooth error corresponds to the near-nullspace of A. Therefore, having a good approximation to a minimal eigenvector is useful to characterize the algebraically smooth error when forming a linear SA solver. This paper discusses the details of a generalized eigensolver based on smoothed aggregation (GES-SA) that is designed to produce an approximation to a minimal eigenvector of A. GES-SA might be very useful as a standalone eigensolver for applications that desire an approximate minimal eigenvector, but the primary aim here is for GES-SA to produce an initial algebraically smooth component that may be used to either create a black-box SA solver or initiate the adaptive SA ({alpha}SA) process.

  1. SPHGR: Smoothed-Particle Hydrodynamics Galaxy Reduction

    Science.gov (United States)

    Thompson, Robert

    2015-02-01

    SPHGR (Smoothed-Particle Hydrodynamics Galaxy Reduction) is a python based open-source framework for analyzing smoothed-particle hydrodynamic simulations. Its basic form can run a baryonic group finder to identify galaxies and a halo finder to identify dark matter halos; it can also assign said galaxies to their respective halos, calculate halo & galaxy global properties, and iterate through previous time steps to identify the most-massive progenitors of each halo and galaxy. Data about each individual halo and galaxy is collated and easy to access. SPHGR supports a wide range of simulations types including N-body, full cosmological volumes, and zoom-in runs. Support for multiple SPH code outputs is provided by pyGadgetReader (ascl:1411.001), mainly Gadget (ascl:0003.001) and TIPSY (ascl:1111.015).

  2. Smooth embeddings with Stein surface images

    CERN Document Server

    Gompf, Robert E

    2011-01-01

    A simple characterization is given of open subsets of a complex surface that smoothly perturb to Stein open subsets. As applications, complex 2-space C^2 contains domains of holomorphy (Stein open subsets) that are exotic R^4's, and others homotopy equivalent to the 2-sphere but cut out by smooth, compact 3-manifolds. Pseudoconvex embeddings of Brieskorn spheres and other 3-manifolds into complex surfaces are constructed, as are pseudoconcave holomorphic fillings (with disagreeing contact and boundary orientations). Pseudoconcave complex structures on Milnor fibers are found. A byproduct of this construction is a simple polynomial expression for the signature of the (p,q,npq-1) Milnor fiber. Akbulut corks in complex surfaces can always be chosen to be pseudoconvex or pseudoconcave submanifods. The main theorem is expressed via Stein handlebodies (possibly infinite), which are defined holomorphically in all dimensions by extending Stein theory to manifolds with noncompact boundary.

  3. Robust Metric Learning by Smooth Optimization

    CERN Document Server

    Huang, Kaizhu; Xu, Zenglin; Liu, Cheng-Lin

    2012-01-01

    Most existing distance metric learning methods assume perfect side information that is usually given in pairwise or triplet constraints. Instead, in many real-world applications, the constraints are derived from side information, such as users' implicit feedbacks and citations among articles. As a result, these constraints are usually noisy and contain many mistakes. In this work, we aim to learn a distance metric from noisy constraints by robust optimization in a worst-case scenario, to which we refer as robust metric learning. We formulate the learning task initially as a combinatorial optimization problem, and show that it can be elegantly transformed to a convex programming problem. We present an efficient learning algorithm based on smooth optimization [7]. It has a worst-case convergence rate of O(1/{\\surd}{\\varepsilon}) for smooth optimization problems, where {\\varepsilon} is the desired error of the approximate solution. Finally, our empirical study with UCI data sets demonstrate the effectiveness of ...

  4. Anisotropic properties of tracheal smooth muscle tissue.

    Science.gov (United States)

    Sarma, P A; Pidaparti, R M; Meiss, R A

    2003-04-01

    The anisotropic (directional-dependent) properties of contracting tracheal smooth muscle tissue are estimated from a computational model based on the experimental data of length-dependent stiffness. The area changes are obtained at different muscle lengths from experiments in which stimulated muscle undergoes unrestricted shortening. Then, through an interative process, the anisotropic properties are estimated by matching the area changes obtained from the finite element analysis to those derived from the experiments. The results obtained indicate that the anisotropy ratio (longitudinal stiffness to transverse stiffness) is about 4 when the smooth muscle undergoes 70% strain shortening, indicating that the transverse stiffness reduces as the longitudinal stiffness increases. It was found through a sensitivity analysis from the simulation model that the longitudinal stiffness and the in-plane shear modulus are not very sensitive as compared to major Poisson's ratio to the area changes of the muscle tissue. Copyright 2003 Wiley Periodicals, Inc.

  5. On smoothness-asymmetric null infinities

    Energy Technology Data Exchange (ETDEWEB)

    Valiente Kroon, Juan Antonio [School of Mathematical Sciences, Queen Mary, University of London, Mile End Road, London E1 4NS (United Kingdom)

    2006-05-21

    We discuss the existence of asymptotically Euclidean initial data sets for the vacuum Einstein field equations which would give rise (modulo an existence result for the evolution equations near spatial infinity) to developments with a past and a future null infinity of different smoothness. For simplicity, the analysis is restricted to the class of conformally flat, axially symmetric initial data sets. It is shown how the free parameters in the second fundamental form of the data can be used to satisfy certain obstructions to the smoothness of null infinity. The resulting initial data sets could be interpreted as those of some sort of (nonlinearly) distorted Schwarzschild black hole. Their developments would be that they admit a peeling future null infinity, but at the same time have a polyhomogeneous (non-peeling) past null infinity.

  6. Quantum state smoothing for classical mixtures

    CERN Document Server

    Tan, D; Mølmer, K; Murch, K W

    2016-01-01

    In quantum mechanics, wave functions and density matrices represent our knowledge about a quantum system and give probabilities for the outcomes of measurements. If the combined dynamics and measurements on a system lead to a density matrix $\\rho(t)$ with only diagonal elements in a given basis $\\{|n\\rangle\\}$, it may be treated as a classical mixture, i.e., a system which randomly occupies the basis states $|n\\rangle$ with probabilities $\\rho_{nn}(t)$. Fully equivalent to so-called smoothing in classical probability theory, subsequent probing of the occupation of the states $|n\\rangle$ improves our ability to retrodict what was the outcome of a projective state measurement at time $t$. Here, we show with experiments on a superconducting qubit that the smoothed probabilities do not, in the same way as the diagonal elements of $\\rho$, permit a classical mixture interpretation of the state of the system at the past time $t$.

  7. Protostellar outflows with Smoothed Particle Magnetohydrodynamics (SPMHD)

    CERN Document Server

    Bürzle, Florian; Stasyszyn, Federico; Dolag, Klaus; Klessen, Ralf S

    2011-01-01

    The protostellar collapse of a molecular cloud core is usually accompanied by outflow phenomena. The latter are thought to be driven by magnetorotational processes from the central parts of the protostellar disc. While several 3D AMR/nested grid studies of outflow phenomena in collapsing magnetically supercritical dense cores have been reported in the literature, so far no such simulation has been performed using the Smoothed Particle Hydrodynamics (SPH) method. This is mainly due to intrinsic numerical difficulties in handling magnetohydrodynamics within SPH, which only recently were partly resolved. In this work, we use an approach where we evolve the magnetic field via the induction equation, augmented with stability correction and divergence cleaning schemes. We consider the collapse of a rotating core of one solar mass, threaded by a weak magnetic field initially parallel to the rotation axis so that the core is magnetically supercritical. We show, that Smoothed Particle Magnetohydrodynamics (SPMHD) is a...

  8. Air flow through smooth and rough cracks

    Energy Technology Data Exchange (ETDEWEB)

    Kula, H.-G.; Sharples, S. [Sheffield Univ. (United Kingdom). Dept. of Building Science

    1994-12-31

    A series of laboratory experiments are described which investigated the effect of surface roughness on the air flow characteristics of simple, straight-through, no-bend cracks with smooth and rough internal surfaces. The crack thicknesses used in the study were 1.0, 1.5 and 2.0mm. The crack lengths, in the direction of flow, were 50.8mm and 76.2mm. For the rough cracks the roughness was simulated with two different grades of commercially available energy-cloth (grade 60 and 100). The experimental results were satisfactorily fitted to a quadratic relationship between {Delta}p and Q of the form {Delta}p = AQ + BQ{sup 2} for both the smooth and rough crack data. The effect of roughness on the reduction of air flowing through a crack is also discussed. (author)

  9. Compensating for estimation smoothing in kriging

    Science.gov (United States)

    Olea, R.A.; Pawlowsky, Vera

    1996-01-01

    Smoothing is a characteristic inherent to all minimum mean-square-error spatial estimators such as kriging. Cross-validation can be used to detect and model such smoothing. Inversion of the model produces a new estimator-compensated kriging. A numerical comparison based on an exhaustive permeability sampling of a 4-fr2 slab of Berea Sandstone shows that the estimation surface generated by compensated kriging has properties intermediate between those generated by ordinary kriging and stochastic realizations resulting from simulated annealing and sequential Gaussian simulation. The frequency distribution is well reproduced by the compensated kriging surface, which also approximates the experimental semivariogram well - better than ordinary kriging, but not as well as stochastic realizations. Compensated kriging produces surfaces that are more accurate than stochastic realizations, but not as accurate as ordinary kriging. ?? 1996 International Association for Mathematical Geology.

  10. Just-in-Time Smoothing Through Batching

    OpenAIRE

    Wieslaw Kubiak; Mesut Yavuz

    2008-01-01

    This paper presents two methods to solve the production smoothing problem in mixed-model just-in-time (JIT) systems with large setup and processing time variability between different models the systems produce. The problem is motivated by production planning at a leading U.S. automotive pressure hose manufacturer. One method finds all Pareto-optimal solutions that minimize total production rate variation of models and work in process (WIP), and maximize system utilization and responsiveness. ...

  11. Virtual Cinematography Using Optimization and Temporal Smoothing

    OpenAIRE

    Litteneker, Alan Ulfers

    2016-01-01

    The problem of automatic virtual cinematography is often approached as an optimization problem. By identifying the extrema of an objective function matching some desired parameters, such as those common in live action photography or cinematography, a suitable camera pose or path can be automatically determined. With several constraints on function form, multiple objective functions can be combined into a single optimizable function, which can be further extended to model the smoothness of the...

  12. GLOBAL SMOOTHNESS PRESERVATION BY BIVARIATE INTERPOLATION OPERATORS

    Institute of Scientific and Technical Information of China (English)

    S.G.Gal; J.Szabados

    2003-01-01

    Extending the results of [4] in the univariate case, in this paper we prove that the bivariate interpolation polynomials of Hermite-Fejer based on the Chebyshev nodes of the first kind, those of Lagrange based on the Chebyshev nodes of second kind and ± 1, and those of bivariate Shepard operators, have the property of partial preservation of global smoothness, with respect to various bivariate moduli of continuity.

  13. Modeling Water Waves with Smoothed Particle Hydrodynamics

    Science.gov (United States)

    2013-09-30

    flows, such as undertow, longshore currents, and rip currents. APPROACH The approach is based on improving various aspects of the SPH code ...Smoothed Particle Hydrodynamics ( SPH ) is a meshless numerical method that is being developed for the study of nearshore waves and other Navy needs. The...Lagrangian nature of SPH allows the modeling of wave breaking, surf zones, ship waves, and wave-structure interaction, where the free surface becomes

  14. The Smooth Muscle of the Artery

    Science.gov (United States)

    1975-01-01

    ruling out the oossibility that depolarization is a junction potential due to rnovement. The low resting potential shown is indicative of the degree of...which is embryologically Soditm Pump in the Con- and functionally related to vascular trol ot %tscle Contrac- smooth muscle, many of the electrical...consideration a 5-hydroxytryptamine as well as histamine as being the factor that we are studying. This does not rule out the posni- bility that either

  15. Robust Filtering and Smoothing with Gaussian Processes

    OpenAIRE

    Deisenroth, Marc Peter; Turner, Ryan; Huber, Marco F.; Hanebeck, Uwe D.; Rasmussen, Carl Edward

    2012-01-01

    We propose a principled algorithm for robust Bayesian filtering and smoothing in nonlinear stochastic dynamic systems when both the transition function and the measurement function are described by non-parametric Gaussian process (GP) models. GPs are gaining increasing importance in signal processing, machine learning, robotics, and control for representing unknown system functions by posterior probability distributions. This modern way of "system identification" is more robust than finding p...

  16. Demosaicing by Smoothing along 1D Features

    OpenAIRE

    Ajdin, Boris; Hullin, Matthias B.; Fuchs, Christian; Seidel, Hans-Peter; Lensch, Hendrik P. A.

    2008-01-01

    Most digital cameras capture color pictures in the form of an image mosaic, recording only one color channel at each pixel position. Therefore, an interpolation algorithm needs to be applied to reconstruct the missing color information. In this paper we present a novel Bayer pattern demosaicing approach, employing stochastic global optimization performed on a pixel neighborhood. We are minimizing a newly developed cost function that increases smoothness along one-dimen...

  17. Random Walk Smooth Transition Autoregressive Models

    OpenAIRE

    2004-01-01

    This paper extends the family of smooth transition autoregressive (STAR) models by proposing a specification in which the autoregressive parameters follow random walks. The random walks in the parameters can capture structural change within a regime switching framework, but in contrast to the time varying STAR (TV-STAR) speciifcation recently introduced by Lundbergh et al (2003), structural change in our random walk STAR (RW-STAR) setting follows a stochastic process rather than a determinist...

  18. A Fast Variational Method for the Construction of Resolution Adaptive C-Smooth Molecular Surfaces.

    Science.gov (United States)

    Bajaj, Chandrajit L; Xu, Guoliang; Zhang, Qin

    2009-05-01

    We present a variational approach to smooth molecular (proteins, nucleic acids) surface constructions, starting from atomic coordinates, as available from the protein and nucleic-acid data banks. Molecular dynamics (MD) simulations traditionally used in understanding protein and nucleic-acid folding processes, are based on molecular force fields, and require smooth models of these molecular surfaces. To accelerate MD simulations, a popular methodology is to employ coarse grained molecular models, which represent clusters of atoms with similar physical properties by psuedo- atoms, resulting in coarser resolution molecular surfaces. We consider generation of these mixed-resolution or adaptive molecular surfaces. Our approach starts from deriving a general form second order geometric partial differential equation in the level-set formulation, by minimizing a first order energy functional which additionally includes a regularization term to minimize the occurrence of chemically infeasible molecular surface pockets or tunnel-like artifacts. To achieve even higher computational efficiency, a fast cubic B-spline C(2) interpolation algorithm is also utilized. A narrow band, tri-cubic B-spline level-set method is then used to provide C(2) smooth and resolution adaptive molecular surfaces.

  19. On the thermodynamics of smooth muscle contraction

    Science.gov (United States)

    Stålhand, Jonas; McMeeking, Robert M.; Holzapfel, Gerhard A.

    2016-09-01

    Cell function is based on many dynamically complex networks of interacting biochemical reactions. Enzymes may increase the rate of only those reactions that are thermodynamically consistent. In this paper we specifically treat the contraction of smooth muscle cells from the continuum thermodynamics point of view by considering them as an open system where matter passes through the cell membrane. We systematically set up a well-known four-state kinetic model for the cross-bridge interaction of actin and myosin in smooth muscle, where the transition between each state is driven by forward and reverse reactions. Chemical, mechanical and energy balance laws are provided in local forms, while energy balance is also formulated in the more convenient temperature form. We derive the local (non-negative) production of entropy from which we deduce the reduced entropy inequality and the constitutive equations for the first Piola-Kirchhoff stress tensor, the heat flux, the ion and molecular flux and the entropy. One example for smooth muscle contraction is analyzed in more detail in order to provide orientation within the established general thermodynamic framework. In particular the stress evolution, heat generation, muscle shorting rate and a condition for muscle cooling are derived.

  20. Notch Signaling in Vascular Smooth Muscle Cells.

    Science.gov (United States)

    Baeten, J T; Lilly, B

    2017-01-01

    The Notch signaling pathway is a highly conserved pathway involved in cell fate determination in embryonic development and also functions in the regulation of physiological processes in several systems. It plays an especially important role in vascular development and physiology by influencing angiogenesis, vessel patterning, arterial/venous specification, and vascular smooth muscle biology. Aberrant or dysregulated Notch signaling is the cause of or a contributing factor to many vascular disorders, including inherited vascular diseases, such as cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy, associated with degeneration of the smooth muscle layer in cerebral arteries. Like most signaling pathways, the Notch signaling axis is influenced by complex interactions with mediators of other signaling pathways. This complexity is also compounded by different members of the Notch family having both overlapping and unique functions. Thus, it is vital to fully understand the roles and interactions of each Notch family member in order to effectively and specifically target their exact contributions to vascular disease. In this chapter, we will review the Notch signaling pathway in vascular smooth muscle cells as it relates to vascular development and human disease.

  1. Potential application of the electronic nose for shelf-life determination of raw milk and red meat

    Science.gov (United States)

    Amari, Aziz; El Barbri, Noureddine; El Bari, Nezha; Llobet, Eduard; Correig, Xavier; Bouchikhi, Benachir

    2009-05-01

    The present study describes the performance of an electronic nose in food odor analysis. This methodology was successfully applied to odor characterization of milk stored at 4° C during 4 days and of beef and sheep meat stored at 4° C for up to 15 days. The electronic nose sensor system coupled to PCA as a pattern recognition technique, is able to reveal characteristic changes in raw milk and red meat quality related to storage time. Additionally, a bacteriological method was selected as the reference method to consistently train the electronic nose system for both beef and sheep meat analysis.

  2. Nasal base narrowing: the alar flap advancement technique.

    Science.gov (United States)

    Ismail, Ahmed Soliman

    2011-01-01

    To evaluate the role of creating an alar-based advancement flap in narrowing the nasal base and correcting excessive alar flare. Case series with chart review. This is a retrospective record review study. The study included 35 cases presenting with a wide nasal base and excessive alar flaring. The surgical procedure combined the alar base reduction with alar flare excision by creating a single laterally based alar flap. Any caudal septal deformities and any nasal tip modification procedures were corrected before the nasal base narrowing. The mean follow-up period was 23 months. The mean alar flap narrowing was 6.3 mm, whereas the mean width of sill narrowing was 2.9 mm. This single laterally based advancement alar flap resulted in a more conservative external resection, thus avoiding alar wedge overresection or blunting of the alar-facial crease. No cases of postoperative bleeding, infection, or keloid were encountered, and the external alar wedge excision healed with no apparent scar that was hidden in the depth of the alar-facial crease. The risk of notching of the alar rim at the sill incision is reduced by adopting a 2-layer closure of the vestibular floor. The alar base advancement flap is an effective technique in narrowing both the nasal base and excessive alar flare. It adopts a single skin excision to correct the 2 deformities while commonly feared complications were avoided.

  3. Smooth Fano polytopes can not be inductively constructed

    DEFF Research Database (Denmark)

    Øbro, Mikkel

    2008-01-01

    We examine a concrete smooth Fano 5-polytope $P$ with 8 vertices with the following properties: There does not exist a smooth Fano 5-polytope $Q$ with 7 vertices such that $P$ contains $Q$, and there does not exist a smooth Fano 5-polytope $R$ with 9 vertices such that $R$ contains $P$. As the po...

  4. Exponential smoothing for financial time series data forecasting

    Directory of Open Access Journals (Sweden)

    Kuzhda, Tetyana Ivanivna

    2014-05-01

    Full Text Available The article begins with the formulation for predictive learning called exponential smoothing forecasting. The exponential smoothing is commonly applied to financial markets such as stock or bond, foreign exchange, insurance, credit, primary and secondary markets. The exponential smoothing models are useful in providing the valuable decision information for investors. Simple and double exponential smoothing models are two basic types of exponential smoothing method. The simple exponential smoothing method is suitable for financial time series forecasting for the specified time period. The simple exponential smoothing weights past observations with exponentially decreasing weights to forecast future values. The double exponential smoothing is a refinement of the simple exponential smoothing model but adds another component which takes into account any trend in the data. The double exponential smoothing is designed to address this type of data series by taking into account any trend in the data. Measurement of the forecast accuracy is described in this article. Finally, the quantitative value of the price per common share forecast using simple exponential smoothing is calculated. The applied recommendations concerning determination of the price per common share forecast using double exponential smoothing are shown in the article.

  5. Alternative Smoothing and Scaling Strategies for Weighted Composite Scores

    Science.gov (United States)

    Moses, Tim

    2014-01-01

    In this study, smoothing and scaling approaches are compared for estimating subscore-to-composite scaling results involving composites computed as rounded and weighted combinations of subscores. The considered smoothing and scaling approaches included those based on raw data, on smoothing the bivariate distribution of the subscores, on smoothing…

  6. Neurophysiology and Neuroanatomy of Smooth Pursuit in Humans

    Science.gov (United States)

    Lencer, Rebekka; Trillenberg, Peter

    2008-01-01

    Smooth pursuit eye movements enable us to focus our eyes on moving objects by utilizing well-established mechanisms of visual motion processing, sensorimotor transformation and cognition. Novel smooth pursuit tasks and quantitative measurement techniques can help unravel the different smooth pursuit components and complex neural systems involved…

  7. Prospects for a Narrow Line MOT in YO

    CERN Document Server

    Collopy, Alejandra L; Yeo, Mark; Yan, Bo; Ye, Jun

    2015-01-01

    In addition to being suitable for laser cooling and trapping in a magneto-optical trap (MOT) using a relatively broad ($\\sim$5 MHz) transition, the molecule YO possesses a narrow-line transition. This forbidden transition between the $X^{2}\\Sigma$ and $A'^{2}\\Delta_{3/2}$ states has linewidth $\\sim$2$\\pi\\times$160 kHz. After cooling in a MOT on the $X^{2}\\Sigma$ to $A^{2}\\Pi_{1/2}$ (orange) transition, the narrow (red) transition can be used to further cool the sample, requiring only minimal additions to the first stage system. The narrow line cooling stage will bring the temperature from $\\sim$1 mK to $\\sim$10 $\\mu$K, significantly advancing the frontier on direct cooling achievable for molecules.

  8. Prospects for a narrow line MOT in YO

    Science.gov (United States)

    Collopy, Alejandra L.; Hummon, Matthew T.; Yeo, Mark; Yan, Bo; Ye, Jun

    2015-05-01

    In addition to being suitable for laser cooling and trapping in a magneto-optical trap (MOT) using a relatively broad (∼ 5 MHz) transition, the molecule YO possesses a narrow-line transition. This forbidden transition between the {{X}2}Σ and A{{\\prime }2}{{Δ }3/2} states has linewidth ∼ 2π × 160 kHz. After cooling in a MOT on the 614 nm {{X}2}Σ to {{A}2}{{\\Pi }1/2} (orange) transition, the narrow 690 nm (red) transition can be used to further cool the sample, requiring only minimal additions to the first stage system. We estimate that the narrow line cooling stage will bring the temperature from ∼1 mK to ∼10 μK, significantly advancing the frontier on direct cooling achievable for molecules.

  9. Temporal intensity interferometry for characterization of very narrow spectral lines

    Science.gov (United States)

    Tan, P. K.; Kurtsiefer, C.

    2017-08-01

    Some stellar objects exhibit very narrow spectral lines in the visible range additional to their blackbody radiation. Natural lasing has been suggested as a mechanism to explain narrow lines in Wolf-Rayet stars. However, the spectral resolution of conventional astronomical spectrographs is still about two orders of magnitude too low to test this hypothesis. We want to resolve the linewidth of narrow spectral emissions in starlight. A combination of spectral filtering with single-photon-level temporal correlation measurements breaks the resolution limit of wavelength-dispersing spectrographs by moving the linewidth measurement into the time domain. We demonstrate in a laboratory experiment that temporal intensity interferometry can determine a 20-MHz-wide linewidth of Doppler-broadened laser light and identify a coherent laser light contribution in a blackbody radiation background.

  10. CT demonstration of pharyngeal narrowing in adult obstructive sleep apnea

    Energy Technology Data Exchange (ETDEWEB)

    Bohlman, M.E. (Johns Hopkins Univ. School of Medicine, Baltimore, MD); Haponik, E.F.; Smith, P.L.; Allen, R.P.; Bleecker, E.R.; Goldman, S.M.

    1983-03-01

    Sleep apnea is a major cause of daytime hypersomnolence. Among the proposed etiologies, focal obstruction of the airways at the level of the pharynx has been suggested but not proven. Using computed tomography, the cross-sectional area of the airway can be readily assessed. Thirty-three adults with clinically proven sleep apnea and 12 normal adults underwent systematic computed tomography of the neck. Significant airway narrowing was demonstrated in all the patients with obstructive sleep apnea, whereas no such narrowing was seen in the controls. In 11, the narrowing was at a single level, whereas in 22 patients two or more levels were affected. This study has shown that a structurally abnormal airway may serve as an anatomic substrate for the development of sleep apnea. On the basis of this evidence, uvulopalatopharyngoplasty has been performed in two patients with relief of symptoms in one.

  11. Multilayer Photonic Crystal for Spectral Narrowing of Emission

    Directory of Open Access Journals (Sweden)

    Zhanfang LIU

    2017-08-01

    Full Text Available Multilayer colloidal crystal has been prepared by the layer-by-layer deposition of silica microspheres on a glass slide. Each layer is a slab consisting of a fcc close-packed colloidal arrays. By properly choosing the sizes of spheres, the whole spectral feature of multilayer colloidal crystal can be tuned. Here, we engineered a multilayer superlattice structure with an effective passband between two stop bands. This gives a strong narrowing effect on emission spectrum. With the stop bands at the shortwave and longwave edges of emission spectrum, the passband in the central wavelength region can be regarded as a strong decrease of suppression effect and enhancement of a narrow wavelength region of emission. The spectral narrowing modification effect of suitably engineered colloidal crystals shows up their importance in potential application as optical filters and lasing devices.DOI: http://dx.doi.org/10.5755/j01.ms.23.3.16320

  12. Thermoviscoelastic dynamic response for a composite material thin narrow strip

    Energy Technology Data Exchange (ETDEWEB)

    Dai, Hong Liang; Qi, Li-Li; Liu, Hai-Bo [Hunan University, Changsha (China)

    2015-02-15

    Based on von Karman nonlinear strain-displacement relationships and classical thin plate theory, a list of nonlinear dynamic equilibrium equations for a viscoelastic composite material thin narrow strip under thermal and mechanic loads are deduced. According to the material constitutive relationship and the relaxation modulus in the form of the Prony series, combing with the Newmark method and the Newton-cotes integration method, a new numerical algorithm for direct solving the whole problem in the time domain is established. By applying this numerical algorithm, the viscoelastic composite material thin narrow strip as the research subject is analyzed systematically, and its rich dynamical behaviors are revealed comprehensively. To verify the accuracy of the present work, a comparison is made with previously published results. Finally, the viscoelastic composite material thin narrow strip under harmonic excitation load and impact load are discussed in detail, and many valuable thermoviscoelastic dynamic characteristics are revealed.

  13. MortalitySmooth: An R Package for Smoothing Poisson Counts with P-Splines

    Directory of Open Access Journals (Sweden)

    Carlo G. Camarda

    2012-07-01

    Full Text Available The MortalitySmooth package provides a framework for smoothing count data in both one- and two-dimensional settings. Although general in its purposes, the package is specifically tailored to demographers, actuaries, epidemiologists, and geneticists who may be interested in using a practical tool for smoothing mortality data over ages and/or years. The total number of deaths over a specified age- and year-interval is assumed to be Poisson-distributed, and P-splines and generalized linear array models are employed as a suitable regression methodology. Extra-Poisson variation can also be accommodated.Structured in an S3 object orientation system, MortalitySmooth has two main functions which t the data and dene two classes of objects:Mort1Dsmooth and Mort2Dsmooth. The methods for these classes (print, summary, plot, predict, and residuals are also included. These features make it easy for users to extract and manipulate the outputs.In addition, a collection of mortality data is provided. This paper provides an overview of the design, aims, and principles of MortalitySmooth, as well as strategies for applying it and extending its use.

  14. Sensitivity and specificity of narrow-band imaging nasoendoscopy compared to histopathology results in patients with suspected nasopharyngeal carcinoma

    Science.gov (United States)

    Adham, M.; Musa, Z.; Lisnawati; Suryati, I.

    2017-08-01

    Nasopharyngeal carcinoma (NPC) is a disease which is prevalent in developing countries like Indonesia. There were 164 new cases of nasopharyngeal carcinoma in the ear, nose, and throat (ENT) oncology outpatient clinic of the Cipto Mangunkusumo hospital in 2014, and 142 cases in 2015. Unfortunately, almost all of these cases presented at an advanced stage. The success of nasopharyngeal carcinoma treatment is largely determined by the stage when patients are diagnosed; it is critical to diagnose NPC as early as possible. Narrow-band imaging (NBI) is an endoscopic instrument with a light system that can improve the visualization of blood vessels of mucosal epithelial malignant tumors. NBI is expected to help clinicians to assess whether a lesion is malignant or not; to do so, it is important to know the value of sensitivity and specificity. This study is a cross-sectional form of a diagnostic test which was performed in the outpatient clinic of the ENT Head and Neck Surgery Department for the Cipto Mangunkusumo Hospital, from January to June 2016, and involved 56 subjects. Patients with a nasopharyngeal mass discovered by physical examination or imaging, and a suspected nasopharyngeal carcinoma were included as a subject. An NBI examination and biopsy was performed locally. Based on this research, NBI could be used as a screening tool for nasopharyngeal carcinoma with high sensitivity (100%), but with a low specificity result (6.7%).

  15. Search for narrow resonances lighter than Upsilon mesons

    Energy Technology Data Exchange (ETDEWEB)

    Aaltonen, T.; /Helsinki Inst. of Phys.; Adelman, Jahred A.; /Chicago U., EFI; Akimoto, T.; /Tsukuba U.; Alvarez Gonzalez, B.; /Cantabria Inst. of Phys.; Amerio, S.; /INFN, Padua; Amidei, Dante E.; /Michigan U.; Anastassov, A.; /Northwestern U.; Annovi, Alberto; /Frascati; Antos, Jaroslav; /Comenius U.; Apollinari, G.; /Fermilab; Apresyan, A.; /Purdue U. /Waseda U.

    2009-03-01

    We report a search for narrow resonances, produced in p{bar p} collisions at {radical}s = 1.96 TeV, that decay into muon pairs with invariant mass between 6.3 and 9.0 GeV/c{sup 2}. The data, collected with the CDF II detector at the Fermilab Tevatron collider, correspond to an integrated luminosity of 630 pb{sup -1}. We use the dimuon invariant mass distribution to set 90% upper credible limits of about 1% to the ratio of the production cross section times muonic branching fraction of possible narrow resonances to that of the {Upsilon}(1S) meson.

  16. Infrared Perfect Ultra-narrow Band Absorber as Plasmonic Sensor

    OpenAIRE

    Wu, Dong; Liu, Yumin; Li, Ruifang; Chen, Lei; Ma, Rui; Liu, Chang; Ye, Han

    2016-01-01

    We propose and numerically investigate a novel perfect ultra-narrow band absorber based on a metal-dielectric-metal-dielectric-metal periodic structure working at near-infrared region, which consists of a dielectric layer sandwiched by a metallic nanobar array and a thin gold film over a dielectric layer supported by a metallic film. The absorption efficiency and ultra-narrow band of the absorber are about 98 % and 0.5 nm, respectively. The high absorption is contributed to localized surface ...

  17. Heat conduction in one-dimensional oscillator lattices using Nose-Hoover chain thermostats

    Energy Technology Data Exchange (ETDEWEB)

    Romero-Bastida, M; Aguilar, J F [Centro de Investigacion en PolImeros, Marcos Achar Lobaton No. 2, Tepexpan, 55885 Acolman, Estado de Mexico (Mexico)

    2006-09-08

    In this work, we numerically study the dynamical evolution and heat transport properties of a system that consists of two time-reversible thermostats connected either by a one-dimensional Fermi-Pasta-Ulam or a Frenkel-Kontorova oscillator lattice, which are representative models of momentum-conserving and nonconserving systems, respectively. The thermostats were described by a chain of variables, Nose-Hoover chains, which enhances the ergodicity of the thermostats in comparison to the Nose-Hoover method. The time evolution of both lattices is not significantly altered by the dynamics of the thermostats. The temperature profile and heat flux of the Fermi-Pasta-Ulam model are more sensitive to the dynamics of the extended variables than those corresponding to the Frenkel-Kontorova model. Nevertheless we reproduce the scaling properties of the thermal conductivity with system size obtained by other authors.

  18. Nose and Midface Augmentation by Rib Cartilage Grafts: Methods and Outcome in 32 Cases

    Directory of Open Access Journals (Sweden)

    Adham Farouk

    2015-01-01

    Full Text Available Recession of the midface is a relatively common condition that can have a negative impact on facial and nasal aesthetic appearance, and it poses a challenge to plastic surgeons. In cases with generalized maxillary retrusion and/or malocclusion, bone advancement surgery is required, but in localized cases, mostly seen in cleft lip patients, the quest is for an ideal material and a proper technique that would be used to augment the receding area. Throughout a period of seven years, thirty-two patients with nose and midface retrusion were managed by a construct of rib cartilage grafts designed to compensate the deficiency at the maxillary, piriform, and premaxillary areas. Results were satisfactory for most patients in terms of improved fullness of malar area, improved nasal tip projection and rotation, and improvement of upper lip. The presented technique of rib cartilage grafting is a safe and effective method for nose and midface augmentation.

  19. Detection of Adulteration in Argan Oil by Using an Electronic Nose and a Voltammetric Electronic Tongue

    Directory of Open Access Journals (Sweden)

    Madiha Bougrini

    2014-01-01

    Full Text Available Adulteration detection of argan oil is one of the main aspects of its quality control. Following recent fraud scandals, it is mandatory to ensure product quality and customer protection. The aim of this study is to detect the percentages of adulteration of argan oil with sunflower oil by using the combination of a voltammetric e-tongue and an e-nose based on metal oxide semiconductor sensors and pattern recognition techniques. Data analysis is performed by three pattern recognition methods: principal component analysis (PCA, discriminant factor analysis (DFA, and support vector machines (SVMs. Excellent results were obtained in the differentiation between unadulterated and adulterated argan oil with sunflower one. To the best of our knowledge, this is the first attempt to demonstrate whether the combined e-nose and e-tongue technologies could be successfully applied to the detection of adulteration of argan oil.

  20. An Analog Multilayer Perceptron Neural Network for a Portable Electronic Nose

    Directory of Open Access Journals (Sweden)

    Chih-Heng Pan

    2012-12-01

    Full Text Available This study examines an analog circuit comprising a multilayer perceptron neural network (MLPNN. This study proposes a low-power and small-area analog MLP circuit to implement in an E-nose as a classifier, such that the E-nose would be relatively small, power-efficient, and portable. The analog MLP circuit had only four input neurons, four hidden neurons, and one output neuron. The circuit was designed and fabricated using a 0.18 μm standard CMOS process with a 1.8 V supply. The power consumption was 0.553 mW, and the area was approximately 1.36 × 1.36 mm2. The chip measurements showed that this MLPNN successfully identified the fruit odors of bananas, lemons, and lychees with 91.7% accuracy.