Prevention of Acute Rheumatic Fever and Rheumatic Heart Disease

Science.gov (United States)

... Patient Page Prevention of Acute Rheumatic Fever and Rheumatic Heart Disease Mariana Mirabel , Kumar Narayanan , Xavier Jouven , Eloi Marijon ... regurgitant ) valves. Over time, there is progressive damage (rheumatic heart disease, RHD) that may lead to heart failure, stroke, ...

Resonance – Journal of Science Education | Indian Academy of ...

Indian Academy of Sciences (India)

Home; Journals; Resonance – Journal of Science Education; Volume 6; Issue 10. Solution to Tangles of Mats and Maths of Rectangles. Mandar Joshi Kshitij Khare Arvind Narayanan Sandeep Varma. Think It Over Volume 6 Issue 10 October 2001 pp 87-91 ...

Large scale features and assessment of spatial scale ...

Indian Academy of Sciences (India)

R Uma1, T V Lakshmi Kumar1, M S Narayanan1,∗, M Rajeevan2,. Jyoti Bhate3 and K ... satellite Precipitation Analysis (TMPA) version 6 and India Meteorological Department (IMD) gridded ... site http://disc.sci.gsfc.nasa.gov/, has provided an.

Fulltext PDF

Indian Academy of Sciences (India)

Simple Trigonometric Identities and Basic Calculus Lead- ing to Interesting Series. R Govindaraj. Can you see Air? Andal Narayanan, Joseph Samuel and Supurna Sinha. Determination of Lifetimes of Carbocations in Aqueous. Solution by Azide Clock: A Simple Physical-Organic Chem- istry Experiment. V Jagannadham.

Journal of Chemical Sciences | Indian Academy of Sciences

Indian Academy of Sciences (India)

... Journals; Journal of Chemical Sciences; Volume 117; Issue 1. Relationship between electrophilicity index, Hammett constant and nucleus-independent chemical shift. M Elango R Parthasarathi G Karthik Narayanan A Md Sabeelullah U Sarkar N S Venkatasubramaniyan V Subramanian P K Chattaraj. Full Papers Volume ...

African Journal of Biotechnology - Vol 5, No 13 (2006)

African Journals Online (AJOL)

Optimization of DNA extraction for ISSR studies in Tectona grandis L.f. - an important forest tree species · EMAIL FREE FULL TEXT EMAIL FREE FULL TEXT DOWNLOAD FULL TEXT DOWNLOAD FULL TEXT. C Narayanan, S Dubey, SA Wali, N Shukla, R Kumar, AK Mandal, SA Ansari ...

Sadhana | Indian Academy of Sciences

Indian Academy of Sciences (India)

Home; Journals; Sadhana. C KUMARESAN. Articles written in Sadhana. Volume 42 Issue 8 August 2017 pp 1263-1273. Theoretical prediction and experimental verification of light-load instability in a 11-kW open-loop induction motor drive · ANIRUDH GUHA ABHISHEK CHETTY C KUMARESAN G NARAYANAN R ...

Sadhana | Indian Academy of Sciences

Indian Academy of Sciences (India)

Home; Journals; Sadhana. R KRISHNAMOORTHY. Articles written in Sadhana. Volume 42 Issue 8 August 2017 pp 1263-1273. Theoretical prediction and experimental verification of light-load instability in a 11-kW open-loop induction motor drive · ANIRUDH GUHA ABHISHEK CHETTY C KUMARESAN G NARAYANAN R ...

Untitled

Indian Academy of Sciences (India)

Algal flora of Vindhyan formations of the Mirzapur District, U.P. (Singh), 66. Apanteles angaleti Muesebeck (Braconidae: Hymenoptera), host selection and oviposition response in (Narayanan and others), 139. Blast disease of rice, the problem of (Sadasivan), 1. Bracon gelechiae Ashmead, insect parasite, labelling of adults ...

Sadhana | Indian Academy of Sciences

Indian Academy of Sciences (India)

Home; Journals; Sadhana. V S S PAVAN KUMAR HARI. Articles written in Sadhana. Volume 42 Issue 8 August 2017 pp 1285-1297. Experimental determination of mechanical parameters in sensorless vector-controlled induction motor drive · V S S PAVAN KUMAR HARI AVANISH TRIPATHI G NARAYANAN · More Details ...

On the overlap formulation of chiral gauge theory

International Nuclear Information System (INIS)

Randjbar Daemi, S.; Strathdee, J.

1994-12-01

The overlap formula proposed by Narayanan and Neuberger in chiral gauge theories is examined. The free chiral and Dirac Green's functions are constructed in this formalism. Four dimensional anomalies are calculated and the usual anomaly cancellation for one standard family of quarks and leptons is verified. (author). 4 refs

Supply Network Enabled Innovation Within a Non-repetitive Manufacturing Context

DEFF Research Database (Denmark)

Kavin, Lone

Afhandlingen tager udgangspunkt i det faktum, at innovation er en vigtig forudsætning for at være vedholdende og succesfuld i et konkurrencepræget og globalt miljø (Ageron et al., 2013; Choi and Krause, 2006; Narasimhan and Narayanan, 2013; Pittaway et al., 2004; Zimmermann et al., 2016). Endvide...

Sadhana | Indian Academy of Sciences

Indian Academy of Sciences (India)

Home; Journals; Sadhana. Anirudh Guha. Articles written in Sadhana. Volume 41 Issue 2 February 2016 pp 125-145. Modelling and analysis of an open-loop induction motor drive incorporating the effect of inverter dead-time · Anirudh Guha G Narayanan · More Details Abstract Fulltext PDF. The objective of this paper is to ...

Can you see Air?

Indian Academy of Sciences (India)

Home; Journals; Resonance – Journal of Science Education; Volume 12; Issue 6. Can you see Air? Andal Narayanan Joseph Samuel Supurna Sinha. Classroom Volume 12 Issue 6 June 2007 pp 71-75. Fulltext. Click here to view fulltext PDF. Permanent link: https://www.ias.ac.in/article/fulltext/reso/012/06/0071-0075 ...

Advanced Training in Mathematics Schools

Indian Academy of Sciences (India)

Mail the completed forms to: Prof. E K Narayanan, Department of Mathematics, Indian Institute of Science, Bangalore. 560012, Tel: 080-22933270,22932711 Fax: 80-23600146, Email: atm@math.iisc.ernet.in so as to reach before 20 April 2006. List of selected candidates will be posted on the websites on 24th April 2006.

M Abdul Khadar

Indian Academy of Sciences (India)

Home; Journals; Bulletin of Materials Science. M Abdul Khadar. Articles written in Bulletin of Materials Science. Volume 23 Issue 5 October 2000 pp 361-367 Nanomaterials. Dielectric properties of nanophase Ag2HgI4 and Ag2HgI4–Al2O3 nanocomposites · S Sankara Narayanan Potty M Abdul Khadar · More Details ...

NITROANILINE FILM-HOLE MODIFIED GLASSY CARBON ...

African Journals Online (AJOL)

substances (such as ascorbic acid, uric acid and so on) that exist together .... stirring the electrolytes in the cell, a small magnetic bar was used in BASi C3 ..... Stephen, A.; Narayanan, V. New electrochemical sensor based on Ni-doped .... Wang, Y.; Li, Y.; Tang, L.; Lu, J.; Li, J. Application of graphene-modified electrode for.

Hepatic Metabolism of Perfluorinated Carboxylic Acids and Polychlorotrifluoroethylene: A Nuclear Magnetic Resonance Investigation in vito

Science.gov (United States)

1994-01-06

L. Narayanan. and B. M. Jamot. ’Effects of Peulluoro-n- octanoic Acid , Perfluoro-n-decanoic Acid , and Clofibrate on Hepatic Phosphorus Metabolism in...pathways and examined the impact of perfluorocarboxylic acid exposure. This investigative strategy will delineate the metabolic effices exerted by...Perfluorinated Carboxylic Acids and Polychlorotrifluoroethylene: A Nuclear Magnetic Resonance Investigation in Vivo Principal Investigator: Nicholas V. Reo

A theoretical study of porphyrin isomers and their core-modified ...

Indian Academy of Sciences (India)

Unknown

Harmjanz M, Gill H S and Scott M J 2000 J. Am. Chem. Soc. 122 10476; Anzenbacher P Jr, Jursikova. K and Sessler J L 2000 J. Am. Chem. Soc. 122 9350;. Gisselbrecht J P, Gross M, Vogel E and Sessler J L. 2000 Inorg. Chem. 39 2850; Anand V G, Pushpan S. K, Venkatraman S, Narayanan S J, Dey A,. Chandrashekar ...

Hypothermia due to limbic system involvement and longitudinal myelitis in a case of Japanese encephalitis: a case report from India

Directory of Open Access Journals (Sweden)

Narayanan S

2017-04-01

Full Text Available Santhosh Narayanan,1 NK Thulaseedharan,1 Gomathy Subramaniam,2 Geetha Panarkandy,1 VK Shameer,1 Arathi Narayanan1 1Department of General Medicine, 2Department of Radiodiagnosis, Government Medical College, Kozhikode, Kerala, India Abstract: Japanese encephalitis (JE is an infectious encephalitis prevalent in Asia. It usually presents with fever, headache, convulsions and extrapyramidal symptoms. Limbic system involvement and hypothermia though common in autoimmune encephalitis have never been reported in JE. We report a case of an 18-year-old girl with no previous comorbidities who presented to us with a history of fever and headache for 1 week duration. She developed bilateral lateral rectus palsy and asymmetric flaccid weakness of all four limbs, after 2 days of admission, which was followed by altered sensorium and intermittent hypothermia. Neuroimaging revealed longitudinal myelitis extending from pons till the L1 level along with bilateral thalamic hemorrhage in brain. Cerebrospinal fluid (CSF was positive for IgM antibody to JE virus. She was treated with supportive measures, but she developed intractable hypothermia and seizures and succumbed to illness after 2 weeks of admission. Keywords: Japanese encephalitis, hypothermia, limbic system

The Analysis of SUCCESS HPON Networks Using the HPON Network Configurator

Directory of Open Access Journals (Sweden)

Rastislav Roka

2013-01-01

Full Text Available NG-PON systems present optical access infrastructures to support various applications of the many service providers. In the near future, we can expect NG-PON technologies with different motivations for developing of HPON networks. The HPON is a hybrid passive optical network in a way that utilizes on a physical layer both TDM and WDM multiplexing principles together. The HPON network utilizes similar or soft revised topologies as TDM-PON architectures. In this first paper, design requirements for SUCCESS HPON networks are introduced. A main part of the paper is dedicated to presentation of the HPON network configurator that allows configurating and analyzing the SUCCESS HPON characteristics from a viewpoint of various specific network parameters. Finally, a short introduction to the comparison of the SUCCESS and SARDANA HPON networks based on simulation results is presented.

Hepatic Metabolism of Perfluorinated Carboxylic Acids and Polychlorotrifluoroethylene: A Nuclear Magnetic Resonance Investigation in Vivo

Science.gov (United States)

1994-01-05

Goecke, L. Narayanan, and B. M. Jarnot. "Effects of Perfluoro-n- octanoic Acid , Perfluoro-n-decanoic Acid , and Clofibrate on Hepatic Phosphorus L...Carboxylic Acids and 4Polychiorotrifluoroethylene: A Nuclear Magnetic Resonance G-AFOSR-90-0148 Investigation in Vivo ,IIC 6. AUTHOR(S a Nicholas V. Reo...Maxim um 200 words) This report outlines our research progress regarding toxicological investigations of perifluoro- n-octanoic acid (PFOA) and

Hepatic Toxicity of Perfluorocarboxylic Acids.

Science.gov (United States)

1996-07-01

1995). 3. N. V. Reo, C. M. Goecke, L. Narayanan, and B. M. Jarnot. "Effects of Perfluoro-n-octanoic Acid , Perfluoro-n-decanoic Acid , and Clofibrate ...Artz, and B. M. Jarnot: "ILiver Phosphorous Metabolic Response to Perfluorocarboxylic Acids and Clofibrate in Rats and Guinea Pigs: A 31 P NMR Study...Peroxisome Induction by Perfluoro-n-decanoic Acid and Clofibrate in the Rat: Proliferation Versus Activity." International Society for the Study of

Hepatic Metabolism of Perfluorinated Carboxylic Acids: A Nuclear Magnetic Resonance Investigation in Vivo

Science.gov (United States)

1995-01-17

Reo, C. M. Goecke, L. Narayanan, and B. M. Jarnot. "Effects of Perfluoro-n- octanoic Acid , Perfluoro-n-decanoic Acid , and Clofibrate on Hepatic...SUBTITLE 7C 5. FUNDING NUMBERS" Hepatic Metabolism of Perfluorinated Carboxylic Acids : A Nuclear Magnetic Resonance Investigation in Vivo G-AFOSR-90-0148 6...octanoic acid (PFOA) and perfluoro-n-decanoic acid (PFDA). These Air Force chemicals belong to a class of CU’. compounds known as peroxisome

Vanishing of Littlewood-Richardson polynomials is in P

OpenAIRE

Adve, Anshul; Robichaux, Colleen; Yong, Alexander

2017-01-01

J. DeLoera-T. McAllister and K. D. Mulmuley-H. Narayanan-M. Sohoni independently proved that determining the vanishing of Littlewood-Richardson coefficients has strongly polynomial time computational complexity. Viewing these as Schubert calculus numbers, we prove the generalization to the Littlewood-Richardson polynomials that control equivariant cohomology of Grassmannians. We construct a polytope using the edge-labeled tableau rule of H. Thomas-A. Yong. Our proof then combines a saturation...

Assessment of the land use/land cover (LU/LC) and mangrove changes along the Mandovi–Zuari Estuarine complex of Goa, India

Digital Repository Service at National Institute of Oceanography (India)

Misra, A.; ManiMurali, R.; Vethamony, P.

. For the former, the general methodology is to apply pre-classification steps for.eg. band ratios, Principal Component Analysis (PCA) etc whereas object oriented includes standard algorithms such as Support Vector Machines (SVM), K Nearest Neighbor (KNN... usage for the population. Several LULC studies covering different regions have been done in India, especially by using Remote Sensing (RS) and Geographical Information Systems (GIS) (Gautam and Narayanan, 1983; Sharma et al., 1984; Jain, 1992...

Introduction to the Mymaridae (Hymenoptera of Bangladesh

Directory of Open Access Journals (Sweden)

John T. Huber

2017-05-01

Full Text Available An identification key to the 15 genera of Mymaridae found so far in Bangladesh is given, based on about 520 specimens collected using yellow pan traps placed in agricultural habitats and at the edge of ponds, mainly at Bangabandhu Sheikh Mujibur Rahman Agricultural University, Gazipur. Species already reported from Bangladesh are listed and three more are added: Acmopolynema orientale (Narayanan, Subba Rao & Kaur, Himopolynema hishimonus Taguchi, and Mymar pulchellum Curtis.

Nanoparticle albumin-bound (nab)-paclitaxel for the treatment of pancreas ductal adenocarcinoma

OpenAIRE

Weekes, Colin; Narayanan,Vignesh

2015-01-01

Vignesh Narayanan,1 Colin D Weekes1,2 1Division of Medical Oncology, Department of Medicine, 2Developmental Therapeutics Program, University of Colorado Cancer Center, University of Colorado School of Medicine, Aurora, CO, USA Abstract: Pancreatic adenocarcinoma is a leading cause of cancer-related mortality worldwide, and surgical resection offers the only chance of cure. Since the majority of patients have unresectable disease at presentation, the emphasis has been on identifying effective...

Is Storage a Solution to End Water Shortage?

Science.gov (United States)

Narayanan, M.

2009-12-01

Water shortage is a problem of supply and demand. Some authors refer to it as Water Scarcity. The author has discussed this in his previous presentation at the 2008 AGU International Conference. Part of it is reproduced here for purposes of clarification. It is important to recognize that water is essential for the survival of all life on earth. Many water-rich states have thought of water conservation as an art that is practiced mainly in the arid states. But one has to recite the famous quote: “You will never miss water till the well runs dry.” Researchers have also concluded that quantity deficiency experienced by groundwater supplies are affecting many communities around the world. Furthermore federal regulations pertaining to the quality of potable or drinking water have become more stringent (Narayanan, 2008). One must observe that water conservation schemes and efficient utilization practices also benefit the environment to a large extent. These water conservation practicies indeed have a short payback period althought it may seem that there is a heavy initial investment is required. Research scientists have studied MARR (Mean Annual River Runoff) pattern over the years and have arrived at some significant conclusions. Vörsömarty and other scientists have indicated that water scarcity exists when the demand to supply ratio exceeds the number 0.4. (Vörsömarty, 2005). Furthermore other researchers claim to have documented a six-fold increase in water use in the United States during the last century. It is interesting to note that the population of the United States has hardly doubled during the last century. This obviously, is indicative of higher living standards. Nevertheless, it also emphasizes an urgent need for establishing a strong, sound, sensible and sustainable management program for utilizing the available water supplies efficiently (Narayanan, 2008). Author of the 1998 book, Last Oasis: Facing Water Scarcity, Dr. Sandra Postel predicts big

Respiratory enzyme activities in the oxygen-deficient waters of the Arabian Sea

Digital Repository Service at National Institute of Oceanography (India)

Shailaja, M.S.

Differential expression of a unique protein by intracellular Mycobacterium t u berculosis complex Sujatha Narayanan ?, *, V. Vishwanath ?,# and P. R. Nar a yanan ? ? Department of Immunology, Tuberculosis R e search Centre, Mayor V. R. Rama... synthesis of macr o phages was inhibited and the protein sy n thesis pa ttern of M. tuberculosis has been analysed. We have ide n tified a mycobacterial protein of molecular weight 17 kDa which was expressed exclusively in the cytosolic fraction...

Grid laser with modified pro re nata injection of bevacizumab and ranibizumab in macular edema due to branch retinal vein occlusion: MARVEL report no 2

OpenAIRE

Narayanan, Raja; Stewart,Michael; Das,Taraprasad; Chhablani,Jay; Jalali,Subhadra; Ali,Mohammad Hasnat; Panchal,Bhavik

2016-01-01

Raja Narayanan,1 Bhavik Panchal,1 Michael W Stewart,2 Taraprasad Das,1 Jay Chhablani,1 Subhadra Jalali,1 Mohd Hasnat Ali3 On behalf of MARVEL study group 1Smt. Kanuri Santhamma Centre for Vitreo Retinal Diseases, L V Prasad Eye Institute, Hyderabad, India; 2Department of Ophthalmology, Mayo Clinic, Jacksonville, FL, USA; 3Department of Biostatistics, L V Prasad Eye Institute, Hyderabad, India Purpose: The purpose of this study was to prospectively study the efficacy of grid laser combined ...

A case report of aphallia with urorectal septum malformation sequence in a newborn: a very rarely seen condition

Directory of Open Access Journals (Sweden)

Sharma D

2015-12-01

Full Text Available Deepak Sharma,1 Ravinder Singh,2 Sweta Shastri3 1Department of Neonatology, Fernandez Hospital, Hyderabad, 2Department of Pediatrics, Civil Hospital, Hisar, Haryana, 3Department of Pathology, NKP Salve Medical College, Nagpur, Maharashtra, India Abstract: Aphallia (absence of penis is an extremely rare abnormality which has rarely been described in medical literature and can be part of the urorectal septum malformation sequence (URSMS. URSMS has hardly been reported in medical literature and includes the absence of perineal and anal openings in association with ambiguous genitalia and urogenital, colonic, and lumbosacral anomalies. This case report tells the importance of detailed examination of infants that are diagnosed with aphallia. We report a case of a newborn who was diagnosed as aphallia with the URSMS syndrome after birth. The neonate had an endocardial cushion defect (atrial septal defect and ventricular septal defect and bilateral agenesis of the kidney. The neonate succumbed to death secondary to hypoplastic lung leading to respiratory failure. Keywords: aphallia, urorectal septum malformation sequence, cloacal membrane, hindgut development, congenital aphallia, anorectal malformation

An occurrence of approx. 74 ka Youngest Toba tephra from the western continental margin of India

Digital Repository Service at National Institute of Oceanography (India)

Pattan, J.N.; Shane, P.; Pearce, N.J.G.; Banakar, V.K.; Parthiban, G.

. Navalgund and Dr M. S. Narayanan du r- ing the course of this work. Useful discussions with Dr P. S. Desai and Dr A. Sarkar are also thankfully acknow l edged. Received 28 July 2000; revised accepted 3 January 2001 An occurrence of ~ 7 4 ka.... The occurrence of Y TT in the west, north - west, south - west and recently north - east in the South China Sea Basin 17 , suggests wind direction du r ing YTT was not in one way. YTT occurred between oxygen isotope stage 5a and 4, a period of ice growth...

1st October 2011 - President of India P. Devisingh Patil at LHC Point 2, welcomed by CERN Director-General R. Heuer.

CERN Multimedia

Maximilien Brice

2011-01-01

The Indian president, Pratibha Devising Patil, visited CERN on 1 October 2011. During her tour she saw, top right, the ALICE experiment (with from left to right Paolo Giubellino, ALICE spokesperson, Chitra Narayanan, Indian Ambassador to Switzerland, Rolf Heuer, CERN’s director-general, Christy Fernandez, secretary to the president, Rajeev Shukla, Indian minister of state for parliamentary affairs, Tapan Nayak, ALICE and VECC, and Felicitas Pauss, CERN’s head of international relations); top left, went underground with Vinod Chohan, from the Accelerator Beam Lines & Areas group, far left, and (back to camera) Steve Myers, director of accelerators and technology at CERN; bottom left, greeted Indian physicists at CERN; finally posing with Indian members of the ALICE and CMS collaborations and Indian officials.

Quantum neural networks: Current status and prospects for development

Science.gov (United States)

Altaisky, M. V.; Kaputkina, N. E.; Krylov, V. A.

2014-11-01

The idea of quantum artificial neural networks, first formulated in [34], unites the artificial neural network concept with the quantum computation paradigm. Quantum artificial neural networks were first systematically considered in the PhD thesis by T. Menneer (1998). Based on the works of Menneer and Narayanan [42, 43], Kouda, Matsui, and Nishimura [35, 36], Altaisky [2, 68], Zhou [67], and others, quantum-inspired learning algorithms for neural networks were developed, and are now used in various training programs and computer games [29, 30]. The first practically realizable scaled hardware-implemented model of the quantum artificial neural network is obtained by D-Wave Systems, Inc. [33]. It is a quantum Hopfield network implemented on the basis of superconducting quantum interference devices (SQUIDs). In this work we analyze possibilities and underlying principles of an alternative way to implement quantum neural networks on the basis of quantum dots. A possibility of using quantum neural network algorithms in automated control systems, associative memory devices, and in modeling biological and social networks is examined.

Is The Water Shortage Crisis Really One of the Most Dangerous?

Science.gov (United States)

Narayanan, M.

2010-12-01

Author of the 1998 book, Last Oasis: Facing Water Scarcity, Dr. Sandra Postel predicts big water availability problems as populations of so-called “water-stressed” countries jump perhaps six fold over the next 30 years. The author has reported on this in his previous AGU presentations. In the next four decades, more than half of the world’s population will have to deal with sever water shortages. The United States has been blessed with several large fresh water lakes. In spite of having this fresh water supply, some states like Arizona could be facing sever fresh water shortages in the next couple of decades. Sid Wilson, general manager of the Central Arizona Project has indicated "It's not a question of if there is a water shortage anymore. It is in reality, when there will be a water shortage. " Several states share water from the Colorado river. The river has limited water supply to cater to the needs of Arizona, Nevada, California, Colorado, New Mexico, Utah and Wyoming. World Health Organization, NASA, Department of the Interior, NOAA and several organizations have observed that there is a real water shortage crisis. This is because the world’s population has tripled in the twentieth century. This has resulted in a six-fold increase of water usage. Fresh water supply is limited. This is because water cannot be replaced with an alternative. It is important to observe that petroleum can be replaced with alternative fuel resources. It is necessary to recognize that fact that irrigation necessitates almost 65% to 70% of water withdrawal. Industry may utilize about 20% and domestic consumption is about 10% Evaporation from reservoirs is also a major factor, depending upon the climate and environment. Therefore there is an urgent need for all the countries to establish a strong, sound, sensible and sustainable management program for utilizing the available water supplies efficiently (Narayanan, 2008). References: Narayanan, Mysore. (2008). Hydrology, Water

Hydrogen sulfide-releasing naproxen suppresses colon cancer cell growth and inhibits NF-κB signaling

Directory of Open Access Journals (Sweden)

Kodela R

2015-08-01

Full Text Available Ravinder Kodela,1 Niharika Nath,2 Mitali Chattopadhyay,1 Diandra E Nesbitt,1 Carlos A Velázquez-Martínez,3 Khosrow Kashfi11Department of Physiology, Pharmacology and Neuroscience, Sophie Davis School of Biomedical Education, City University of New York Medical School, 2Department of Life Sciences, New York Institute of Technology, New York, NY, USA; 3Faculty of Pharmacy and Pharmaceutical Sciences, University of Alberta, Edmonton, AB, Canada Abstract: Colorectal cancer (CRC is the second leading cause of death due to cancer and the third most common cancer in men and women in the USA. Nuclear factor kappa B (NF-κB is known to be activated in CRC and is strongly implicated in its development and progression. Therefore, activated NF-κB constitutes a bona fide target for drug development in this type of malignancy. Many epidemiological and interventional studies have established nonsteroidal anti-inflammatory drugs (NSAIDs as a viable chemopreventive strategy against CRC. Our previous studies have shown that several novel hydrogen sulfide-releasing NSAIDs are promising anticancer agents and are safer derivatives of NSAIDs. In this study, we examined the growth inhibitory effect of a novel H2S-releasing naproxen (HS-NAP, which has a repertoire as a cardiovascular-safe NSAID, for its effects on cell proliferation, cell cycle phase transitions, and apoptosis using HT-29 human colon cancer cells. We also investigated its effect as a chemopreventive agent in a xenograft mouse model. HS-NAP suppressed the growth of HT-29 cells by induction of G0/G1 arrest and apoptosis and downregulated NF-κB. Tumor xenografts in mice were significantly reduced in volume. The decrease in tumor mass was associated with a reduction of cell proliferation, induction of apoptosis, and decreases in NF-κB levels in vivo. Therefore, HS-NAP demonstrates strong anticancer potential in CRC. Keywords: nonsteroidal anti-inflammatory drugs, cell cycle, apoptosis, xenograft, NF

Probing the biocompatibility of MoS2 nanosheets by cytotoxicity assay and electrical impedance spectroscopy

Science.gov (United States)

Shah, Pratikkumar; Narayanan, Tharangattu N.; Li, Chen-Zhong; Alwarappan, Subbiah

2015-08-01

Transition metal dichalgogenides such as MoS2 have recently emerged as hot two-dimensional (2D) materials due to their superior electronic and catalytic properties. Recently, we have reported the usefulness of MoS2 nanosheets toward the electrochemical detection of neurotransmitters and glucose (Narayanan et al 2014 Nanotechnology 25 335702). Furthermore, there are reports available in the literature that demonstrate the usefulness of MoS2 nanosheets for biosensing and energy storage applications (Zhu et al 2013 J. Am. Chem. Soc. 135 5998-6001 Pumera and Loo 2014 Trends Anal. Chem. 61 49-53 Lee et al 2014 Sci. Rep. 4 7352; Stephenson et al 2014 Energy Environ. Sci. 7 209-31). Understanding the cytotoxic effect of any material is very important prior to employing them for any in vivo biological applications such as implantable sensors, chips, or carriers for drug delivery and cell imaging purposes. Herein, we report the cytotoxicity of the MoS2 nanosheets based on the cytotoxic assay results and electrical impedance analysis using rat pheochromocytoma cells (PC12) and rat adrenal medulla endothelial cells (RAMEC). Our results indicated that the MoS2 nanosheets synthesized in our work are safe 2D nanosheets for futuristic biomedical applications.

Imaging for understanding speech communication: Advances and challenges

Science.gov (United States)

Narayanan, Shrikanth

2005-04-01

Research in speech communication has relied on a variety of instrumentation methods to illuminate details of speech production and perception. One longstanding challenge has been the ability to examine real-time changes in the shaping of the vocal tract; a goal that has been furthered by imaging techniques such as ultrasound, movement tracking, and magnetic resonance imaging. The spatial and temporal resolution afforded by these techniques, however, has limited the scope of the investigations that could be carried out. In this talk, we focus on some recent advances in magnetic resonance imaging that allow us to perform near real-time investigations on the dynamics of vocal tract shaping during speech. Examples include Demolin et al. (2000) (4-5 images/second, ultra-fast turbo spin echo) and Mady et al. (2001,2002) (8 images/second, T1 fast gradient echo). A recent study by Narayanan et al. (2004) that used a spiral readout scheme to accelerate image acquisition has allowed for image reconstruction rates of 24 images/second. While these developments offer exciting prospects, a number of challenges lie ahead, including: (1) improving image acquisition protocols, hardware for enhancing signal-to-noise ratio, and optimizing spatial sampling; (2) acquiring quality synchronized audio; and (3) analyzing and modeling image data including cross-modality registration. [Work supported by NIH and NSF.

Designing Writing Exercises to Emphasize Environmental Education

Science.gov (United States)

Narayanan, M.

2008-12-01

in a learning environment that enables them to acquire real-world problem-solving skills (Saxe, 1988; Senge, 1990; Sims, 1995). Educators should not allow the students to wonder whether they have been learning anything that would actually serve them in the workplace, upon graduation. (Barr and Tagg, 1995). Howard Gardner's list of Eight Intelligences is given below. 1. Linguistic intelligence ("word smart") 2. Logical intelligence ("number smart") 3. Spatial intelligence ("picture smart") 4. Kinesthetic intelligence ("body smart") 5. Musical intelligence ("music smart") 6. Interpersonal intelligence ("people smart") 7. Intrapersonal intelligence ("self smart") 8. Naturalist intelligence ("nature smart") The author has tried to examine students' learning development, behavior and exploration using some of the above eight Intelligences. In this presentation, he provides data he has collected while teaching certain selected courses (Narayanan, 2007). References Gardner, Howard. Frames of Mind: The Theory of Multiple Intelligences. New York: Basic,1983 Gardner, Howard. Multiple Intelligences: The Theory in Practice. New York: Basic, 1993. Gardner, Howard. Intelligence Reframed: Multiple Intelligences for the 21st Century. New York: Basic, 2000. Barr, R. B., and Tagg, J. (1995, November/December). From teaching to learning: A new paradigm for undergraduate education. Change: The Magazine of Higher Education, 13-24. Narayanan, Mysore (2007). Assessment of Perceptual Modality Styles. Proceedings of ASEE 2007 Annual Conference, Honolulu, Hawaii.

The "black evil" affecting patients with diabetes: a case of rhino orbito cerebral mucormycosis causing Garcin syndrome

Directory of Open Access Journals (Sweden)

Narayanan S

2017-03-01

Full Text Available Santhosh Narayanan,1 Geetha Panarkandy,1 Gomathy Subramaniam,2 Chandni Radhakrishnan,1 NK Thulaseedharan,1 Neeraj Manikath,1 Sreejith Ramaswamy,1 Suma Radhakrishnan,3 Danish Ekkalayil1 1Department of General Medicine, 2Department of Radiodiagnosis, 3Department of Otorhinolaryngology, Government Medical College, Kozhikode, Kerala, India Abstract: Mucormycosis is a life-threatening infection affecting patients with diabetes. It is an angioinvasive disease often resistant to treatment with a debilitating course and high mortality. Here, we report a case of a 45 year old woman with type 2 diabetes mellitus who presented to us with history of right-sided ptosis and facial palsy, and subsequently developed loss of vision and palatal palsy. She was in diabetic ketoacidosis. Nervous system examination revealed involvement of right second, third, fourth, sixth, seventh, ninth, and tenth cranial nerves, suggestive of Garcin syndrome. The hard palate had been eroded with formation of black eschar. Computed tomography of paranasal sinuses revealed right maxillary and ethmoid sinusitis, with spread of inflammation to infratemporal fossa and parapharynygeal neck spaces. Debridement of sinus mucosa was done, and culture of the same yielded growth of rhizopus species. Histopathological examination of the tissue showed angioinvasion and fungal hyphae suggestive of mucormycosis. She was treated with amphotericin B, posaconazole, and periodic nasal sinus debridement, but her general condition worsened after 8 weeks due to secondary sepsis and she succumbed to death. Keywords: diabetes, rhinoorbitocerebral, mucormycosis, garcin syndrome

Design of multiligand inhibitors for the swine flu H1N1 neuraminidase binding site

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Narayanan MM

2013-08-01

Full Text Available Manoj M Narayanan,1,2 Chandrasekhar B Nair,2 Shilpa K Sanjeeva,2 PV Subba Rao,2 Phani K Pullela,1,2 Colin J Barrow11Centre for Chemistry and Biotechnology, Deakin University, Geelong, VIC, Australia; 2Bigtec Pvt Ltd, Rajajinagar, Bangalore, IndiaAbstract: Viral neuraminidase inhibitors such as oseltamivir and zanamivir prevent early virus multiplication by blocking sialic acid cleavage on host cells. These drugs are effective for the treatment of a variety of influenza subtypes, including swine flu (H1N1. The binding site for these drugs is well established and they were designed based on computational docking studies. We show here that some common natural products have moderate inhibitory activity for H1N1 neuraminidase under docking studies. Significantly, docking studies using AutoDock for biligand and triligand forms of these compounds (camphor, menthol, and methyl salicylate linked via methylene bridges indicate that they may bind in combination with high affinity to the H1N1 neuraminidase active site. These results also indicate that chemically linked biligands and triligands of these natural products could provide a new class of drug leads for the prevention and treatment of influenza. This study also highlights the need for a multiligand docking algorithm to understand better the mode of action of natural products, wherein multiple active ingredients are present.Keywords: neuraminidase, influenza, H1N1, multiligand, binding energy, molecular docking, virus

Techno-Economic Analysis of Solar Absorption Cooling for Commercial buildings in India

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Muthalagappan Narayanan

2017-11-01

Full Text Available Space cooling and heating always tends to be a major part of the primary energy usage. By using fossil fuel electricity for these purposes, the situation becomes even worse. One of the major electricity consumptions in India is air conditioning. There are a lot of different technologies and few researchers have come up with a debate between solar absorption cooling and PV electric cooling. In a previous paper, PV electric cooling was studied and now as a continuation, this paper focuses on solar thermal absorption cooling systems and their application in commercial/office buildings in India. A typical Indian commercial building is taken for the simulation in TRNSYS. Through this simulation, the feasibility and operational strategy of the system is analysed, after which parametric study and economic analysis of the system is done. When compared with the expenses for a traditional air conditioner unit, this solar absorption cooling will take 13.6 years to pay back and will take 15.5 years to payback the price of itself and there after all the extra money are savings or profit.  Although the place chosen for this study is one of the typical tropical place in India, this payback might vary with different places, climate and the cooling demand. Article History: Received May 12th 2017; Received in revised form August 15th 2017; Accepted 1st Sept 2017; Available online How to Cite This Article: Narayanan, M. (2017. Techno-Economic Analysis of Solar Absorption Cooling for Commercial Buildings in India.  International Journal of Renewable Energy Development, 6(3, 253-262. https://doi.org/10.14710/ijred.6.3.253-262

Nanoparticle albumin-bound (nab-paclitaxel for the treatment of pancreas ductal adenocarcinoma

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Narayanan V

2015-01-01

Full Text Available Vignesh Narayanan,1 Colin D Weekes1,2 1Division of Medical Oncology, Department of Medicine, 2Developmental Therapeutics Program, University of Colorado Cancer Center, University of Colorado School of Medicine, Aurora, CO, USA Abstract: Pancreatic adenocarcinoma is a leading cause of cancer-related mortality worldwide, and surgical resection offers the only chance of cure. Since the majority of patients have unresectable disease at presentation, the emphasis has been on identifying effective chemotherapy regimens to prolong survival and control tumor burden. Gemcitabine has been the cornerstone of treatment ever since it was discovered to be an active agent in advanced pancreatic cancer nearly two decades ago, but the overall prognosis in patients with metastatic disease remains dismal. A dense fibrotic stroma around the tumor devoid of vasculature and the resultant hypoxic tumor microenvironment are implicated in the chemotherapy-resistant nature of this malignancy. In recent years, a growing body of literature has further elucidated several aspects of pancreatic tumor biology, such as its ability to utilize albumin from the peritumoral tissues to support its metabolic needs. High-pressure homogenization of paclitaxel with nanoparticle albumin results in the formation of soluble 130 nm complexes with albumin acting as the carrier for the otherwise hydrophobic paclitaxel. Once these complexes reach the tumor milieu, they act by depleting the tumor stroma. In addition, paclitaxel is also transported into the tumor cell along with albumin, where it then exerts its antineoplastic activity. Nanoparticle albumin-bound (nab-paclitaxel also increases gemcitabine levels inside the tumor cells by inhibiting cytidine deaminase, the enzyme that degrades gemcitabine. This review focuses on proposed mechanisms of efficacy of nab-paclitaxel in pancreatic cancer and discusses the preclinical and clinical studies of relevance. Keywords: pancreatic

Disease burden and patient reported outcomes among patients with moderate to severe psoriasis: an ethnography study

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Narayanan S

2014-12-01

Full Text Available Siva Narayanan,1 Victoria Guyatt,2 Alessandra Franceschetti,3 Emily L Hautamaki1 1Ipsos Healthcare, Columbia, MD, USA; 2Ipsos Ethnography Centre of Excellence (ECE, London, UK; 3Ipsos Healthcare, London, UK Objectives: To assess the impact of psoriasis on health-related quality of life (HRQoL.Methods: An ethnographic study of patients with moderate to severe psoriasis was conducted in the US, France, Germany, Italy, Spain, UK, Brazil, and Canada to explore patients' views on treatment and the impact of psoriasis on HRQoL. Anthropologists and ethnographers spent a minimum of 5.5 hours with each consented patient and filmed their behaviors in everyday situations. Visual data and notes were analyzed to identify HRQoL-related themes.Results: The study included 50 adult patients. Patients described their appearance with disgust and self-loathing. Frustration was expressed due to a perceived lack of control of their lives. Prior to initiation of biologic treatment, daily rituals absorbed a good part of their day, including applying creams, checking one's appearance, and covering the body. Due to a lack of cultural discourse and patient's difficulty in articulating the impact of psoriasis, partners and family did not know how to react nor did they realize the full extent of the problem, and many patients experienced perceived social discrimination due to psoriasis, leaving them with feelings of isolation. Patients established on biologic treatment noticed a significant physical improvement and regained confidence, but psychosocial impacts, including social isolation, remained.Conclusion: This ethnographic study vividly depicted the unarticulated and emotional impact of psoriasis on the everyday lives of patients and presents an effective method of assessing HRQoL in chronic diseases.Keywords: psoriasis, health-related quality of life, ethnography, patient reported outcomes, conceptual model

Is there a crisis in American Higher Education?

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Narayanan, M.; Crawford, L.

2015-12-01

According to the Spellings Commission, the answer to the above question is yes. The commission declared that a crisis exists in American higher education. In their report published in 2005, they claim that colleges and universities are becoming less accessible and less accountable. They indicate that colleges and universities are failing to prepare the students to meet the demanding challenges of the present day workforce and are struggling to maintain an international status (Johnson, K. 2013). The Spellings Report called for information about the quality and cost of college degrees. Authors, Richard Arum and Josipa Roksa claim that American students are learning very little during their first two years of college. Higher education in the United States is examined by these two authors. Josipa Roksa is an Associate Professor of Sociology and Education at the University of Virginia. She is currently serving as Special Advisor to the Provost and Associate Director of the Center for Advanced Study of Teaching and Learning in Higher Education. Richard Arum is an American sociologist who is currently professor of sociology and education at New York University. Arum is also a senior fellow at the Bill and Melinda Gates Foundation. Their research draws on transcript data, the Collegiate Learning Assessment, and survey responses from more than 2,300 undergraduates at twenty-four institutions in their first semester and again at the end of their second year. The analysis reveals that 45 percent of these students demonstrated no significant improvement in a range of skills--including critical thinking, complex reasoning, and writing--during their first two years of college (Arum and Roksa, 2011). (Co-author: Dr. Mysore Narayanan) References: Johnson, Kristine (2013) "Why Students Don't Write: Educating in the Era of Credentialing: Academically Adrift: Limited Learning on College Campuses," Conversations on Jesuit Higher Education: Vol. 43, Article 9. Available at: http

Consequences of Not Conserving Water

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Narayanan, M.; Crawford, L.

2015-12-01

The problem of fresh water is not only local, but also global. In certain parts of the world, much needed rain is becoming less frequent, possibly due to the effects of global warming. The resources of clean fresh water on earth are very limited and are reducing every year due to pollution like industrial waste, oil spills, untreated sewage, inefficient irrigation systems, waste and leakage, etc. This is destroying the ecosystem of the entire planet. Of course, in some parts of world there is rain almost throughout the year. Regardless, major problems are still prevalent because of a variety of reasons such as drainage, storage, evaporation, cleanliness, etc. It is all too well known that evapotranspiration contributes to a significant water loss from drainage basins. Most of the citizens of this world are still careless about water usage and are unappreciative of the need for water conservation. This is a very unpleasant fact and needs to change. Cost expenditures for the development of infrastructure to supply water to households and industries are becoming prohibitively expensive. Many parts in this world have extremely dry terrain and rainfall is not as frequent as it should be. As a result, the underground water tables are not replenished properly, thereby turning regions to arid land and deserts. Unless effective irrigation methods are used, potential evapotranspiration may be actually greater than precipitation provided by nature. The soil therefore dries out creating an arid landmass. The earth and its inhabitants can sustain only if creative methods of clean water conservation ideas are effectively implemented. (Co-author: Dr. Mysore Narayanan) References: http://www.epa.gov/oaintrnt/water/http://www.usda.gov/wps/portal/usda/usdahome?navid=conservationhttp://www.ecy.wa.gov/programs/wr/ws/wtrcnsv.htmlhttp://www.sandiego.gov/water/conservation/http://www.swcs.org/http://www.awwa.org/resources-tools/water-knowledge/water-conservation.aspxhttp://www.benefits-of-recycling.com/waterconservationmethods/

Regulation of human lung fibroblast C1q-receptors by transforming growth factor-beta and tumor necrosis factor-alpha.

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Lurton, J; Soto, H; Narayanan, A S; Raghu, G

1999-03-01

Transforming growth factor-beta (TGF-beta) and tumor necrosis factor-alpha (TNF-alpha) are two polypeptide mediators which are believed to play a role in the evolution of idiopathic pulmonary fibrosis (IPF). We have evaluated the effect of these two substances on the expression of receptors for collagen (cC1q-R) and globular (gC1q-R) domains of C1q and on type I collagen in human lung fibroblasts. Two fibroblast subpopulations differing in C1q receptor expression were obtained by culturing human lung explants in medium containing fresh human serum and heated plasma-derived serum and separating them based on C1q binding [Narayanan, Lurton and Raghu: Am J Resp Cell Mol Biol. 1998; 17:84]. The cells, referred to as HH and NL cells, respectively, were exposed to TGF-beta and TNF-alpha in serum-free conditions. The levels of mRNA were assessed by in situ hybridization and Northern analysis, and protein levels compared after SDS-polyacrylamide gel electrophoresis and Western blotting. NL cells exposed to TGF-beta and TNF-alpha contained 1.4 and 1.6 times as much cC1q-R mRNA, respectively, whereas in HH cells cC1q-R mRNA increased 2.0- and 2.4-fold. The gC1q-R mRNA levels increased to a lesser extent in both cells. These increases were not reflected in protein levels of CC1q-R and gC1q-R, which were similar to or less than controls. Both TGF-beta and TNF-alpha also increased procollagen [I] mRNA levels in both cells. Overall, TNF-alpha caused a greater increase and the degree of response by HH fibroblasts to both TGF-beta and TNF-alpha was higher than NL cells. These results indicated that TGF-beta and TNF-alpha upregulate the mRNA levels for cC1q-R and collagen and that they do not affect gC1q-R mRNA levels significantly. They also indicated different subsets of human lung fibroblasts respond differently to inflammatory mediators.

Grid laser with modified pro re nata injection of bevacizumab and ranibizumab in macular edema due to branch retinal vein occlusion: MARVEL report no 2

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Narayanan R

2016-06-01

Full Text Available Raja Narayanan,1 Bhavik Panchal,1 Michael W Stewart,2 Taraprasad Das,1 Jay Chhablani,1 Subhadra Jalali,1 Mohd Hasnat Ali3 On behalf of MARVEL study group 1Smt. Kanuri Santhamma Centre for Vitreo Retinal Diseases, L V Prasad Eye Institute, Hyderabad, India; 2Department of Ophthalmology, Mayo Clinic, Jacksonville, FL, USA; 3Department of Biostatistics, L V Prasad Eye Institute, Hyderabad, India Purpose: The purpose of this study was to prospectively study the efficacy of grid laser combined with intravitreal bevacizumab or ranibizumab in eyes with macular edema due to branch retinal vein occlusion.Patients and methods: Treatment-naïve eyes were enrolled to receive injections of ranibizumab or bevacizumab. During the first 6 months, patients were evaluated monthly and injected if the best-corrected visual acuity changed by five or more letters or fluid was noted on spectral domain optical coherence tomography (OCT; during the next 6 months, patients were evaluated bimonthly and injected only if the best-corrected visual acuity decreased by five or more letters with the associated fluid. Grid laser photocoagulation was performed if there was fluid on OCT and was repeated if patients were eligible after a minimum interval of 3 months.Results: The mean numbers of ranibizumab and bevacizumab injections were, respectively, 3.2±1.5 and 3.0±1.4 in the first 6 months and 0.3±0.6 and 0.3±0.6 in the last 6 months. ­Moreover, 55/75 (73.33% participants did not receive any injections in the last 6 months. The mean reductions in central retinal thickness at 12 months were 165.67 µm (P<0.001; 95% ­confidence interval -221.50 to -135.0 in the ranibizumab group and 184.78 µm (P<0.001; 95% confidence interval -246.49 to -140.0 in the bevacizumab group (P=0.079. More patients in the bevacizumab group compared to those in the ranibizumab group required rescue laser at 12 months (20 vs eleven; P=0.06.Conclusion: Bimonthly evaluations after month 6

Learn, how to learn

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Narayanan, M.

2002-12-01

. Maintain Momentum. 13. Feedback : Communication. 14. Fact - Based Decisions. 15. Exploit Opportunities. 16. Mobilization of Expertise. 17. Drive out Fear. 18. Recognition / Keep Score. 19. Identify Accomplishments. 20. Customer Focus / Results. In conclusion, the author believes that the ACORN model and the QUOTES model may offer some guidelines that would help and enable the instructor to motivate learners to learn on their own. References Boyer, Ernest L. (1990). Scholarship reconsidered: Priorities of the Professorate. Princeton, NJ: Carnegie Foundation for the Advancement of Teaching. Hawkins, P., and Winter, J. (1997). Mastering change: Learning the lessons of the enterprise in higher education initiative. London: Department for Education and Employment. Narayanan, Mysore (2002). Total Quality Management (TQM) and the Teaching Professor. Oxford, Ohio. : Mimi University : 22nd Annual Lilly Conference on College Teaching.

Dexamethasone-(C21-phosphoramide-[anti-EGFR]: molecular design, synthetic organic chemistry reactions, and antineoplastic cytotoxic potency against pulmonary adenocarcinoma (A549

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Coyne CP

2016-08-01

Full Text Available Cody P Coyne,1 Lakshmi Narayanan2 1Department of Basic Sciences, 2Department of Clinical Sciences, College of Veterinary Medicine, Mississippi State University, Starkville, MS, USA Purpose: Corticosteroids are effective in the management of a variety of disease states, such as several forms of neoplasia (leukemia and lymphoma, autoimmune conditions, and severe inflammatory responses. Molecular strategies that selectively “target” delivery of corticosteroids minimize or prevents large amounts of the pharmaceutical moiety from passively diffusing into normal healthy cell populations residing within tissues and organ systems. Materials and methods: The covalent immunopharmaceutical, dexamethasone-(C21-phosphoramide-[anti-EGFR] was synthesized by reacting dexamethasone-21-monophosphate with a carbodiimide reagent to form a dexamethasone phosphate carbodiimide ester that was subsequently reacted with imidazole to create an amine-reactive dexamethasone-(C21-phosphorylimidazolide intermediate. Monoclonal anti-EGFR immunoglobulin was combined with the amine-reactive dexamethasone-(C21-phosphorylimidazolide intermediate, resulting in the synthesis of the covalent immunopharmaceutical, dexamethasone-(C21-phosphoramide-[anti-EGFR]. Following spectrophotometric analysis and validation of retained epidermal growth factor receptor type 1 (EGFR-binding avidity by cell-ELISA, the selective anti-neoplasic cytotoxic potency of dexamethasone-(C21-phosphoramide-[anti-EGFR] was established by MTT-based vitality stain methodology using adherent monolayer populations of human pulmonary adenocarcinoma (A549 known to overexpress the tropic membrane receptors EGFR and insulin-like growth factor receptor type 1. Results: The dexamethasone:IgG molar-incorporation-index for dexamethasone-(C21-phosphoramide-[anti-EGFR] was 6.95:1 following exhaustive serial microfiltration. Cytotoxicity analysis: covalent bonding of dexamethasone to monoclonal anti-EGFR immunoglobulin

Importance of Technical Writing in Engineering Education

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Narayanan, M.

2010-12-01

., Grasha, A., & Richlin, L. (1997, March). Town meeting. Between teaching model and learning model: Adapting and adopting bit by bit. Paper presented at the ninth annual Lilly Conference on College and University Teaching - West, Lake Arrowhead, CA. Narayanan, Mysore (2009). Assessment Based on the principles of Theodore Marchese. ASEE 116th Annual Conference and Exposition, Austin, TX. June 14-17, 2009. Paper # AC 2009-1532. Saxe, S. (1990, June). Peer influence and learning. Training and Development Journal, 42 (6), 50-53. Senge, P. M. (1990). The fifth discipline: The art and practice of the learning organization. New York: Currency Doubleday. Sims, R. R. (1992, Fall). Developing the learning climate in public sector training programs. Public Personnel Management, 21 (3), 335-346. Kosakowski, John, (1998). The Benefits of Information Technology. ERIC Digests; Technology Integration; Technology Role, ED0-IR-98-04 Chaika, Gloria (2000), Encourage Student Writing: Published on the Web, Education World http://www.education-world.com/a_tech/tech042.shtml

THE ENGLISH LEARNING MOTIVATION AND ATTITUDE TOWARD ENGLISH OF D3 NURSING SCIENCE STUDENTS IN PALEMBANG, SOUTH SUMATRA

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Agus Wahyudi

2017-03-01

Full Text Available Language proficiency is a person’s skill in using a language for a specific purpose (Richards, 1997. One of the tests used to measure the students’ English proficiency is TOEFL. The purpose of the Test of English as a Foreign Language (TOEFL is to evaluate the English proficiency of people whose native language is not English. Over a period of three years from 2007 to 2009, one of the education Companies called Education First (EF ranked the English proficiency among a broad population in 44 countries and territories. The results showed that Asia’s performance was lower than expected, in light of the amount spent on private English training and Indonesia was in the 34th rank or in the very low proficiency level out of 44 countries and territories in the survey (EF : 2011 There are many factors that might cause the students’ low proficiency in English, two of which are students’ motivation and attitude toward English. ‘Motivation’ is the reason or reasons behind one’s actions or behavior, it is a powerful affective variable in second language acquisition, and it has a great influence on second language learning. In order to collect the data, the researcher uses a motivation questionnaire to measure students’ motivation which consists of 40 structured questions (items adapted from Ethel Ogane & Masako Sakamoto (1997. ‘Attitude’ is defined as a disposition or tendency to respond positively or negatively towards a certain thing (idea, object, person, or situation. In order to collect the data, the researcher uses an attitude questionnaire to measure students’ attitude. It consists of 33 structured questions (items adapted from R. Narayanan (2008 which is developed from the Attitude/Motivation Test Battery of Gardner and Lambert and the questionnaires are calculated through Likert Scale. The population of this study is the 1st, 3rd, and 5th semester students of D3

21st Century Water Conservation Principles

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Narayanan, M.

2013-12-01

report details key priorities for the Agency: Many researchers are of the opinion that applying the principles of free market enterprise to water conservation ideas would result in a more efficient utilization of water supply and distribution everywhere. References: EPA's June 2011 Strategic Sustainability Performance Plan (SSPP) (PDF) (74 pp, 1MB) June 2010 EPA Strategic Sustainability Performance Plan (PDF) (67 pp, 3.8MB) U.S. EPA Policy Statement on Climate-Change Adaptation (PDF) (3pp, 55KB) Narayanan, Mysore. (2008). Hydrology, Water Scarcity and Market Economics. 68th AGU International Conference. Eos Transactions: American Geophysical Union, Vol. 89, No. 53, Fall Meeting Supplement, 2009. H11E - 0801. Postel, Sandra L. The Last Oasis: Facing Water Scarcity. New York: W. W. Norton and Company. 1997. Falkenmark, M.J. and Rockström, J. (2004). Balancing Water For Humans and Nature. Sterling, VA. Earthscan. Giordano, M. (2006) Agricultural Groundwater Use and Rural Livelihoods Journal of Hydrogeology. 14, 310 - 318. Allan, J.A. (2003). Virtual Water. Useful Concept or Misleading Metaphor? Water International. 28, 4-11. Vörsömarty, C.J., Douglas, E.M., Green, P.A. and Revenga, C. 2005. Geospatial Indicators of Energing Water Stress. Ambio, 34. 230-236.

The Importance of Water Conservation in the 21st Century

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Narayanan, M.

2012-12-01

Performance Plan. The report details key priorities for the Agency: 1. GHG emissions inventories and reduction through energy efficiency, renewable energy, and transportation management. 2. High-performance sustainable buildings. 3. Regional and local planning. 4. Water conservation. 5. Recycling and pollution prevention. 6. Sustainable acquisition. 7. Electronics stewardship. Many researchers are of the opinion that applying the principles of free market enterprise to water conservation ideas would result in a more efficient utilization of water supply and distribution everywhere. References: EPA's June 2011 Strategic Sustainability Performance Plan (SSPP) (PDF) (74 pp, 1MB) June 2010 EPA Strategic Sustainability Performance Plan (PDF) (67 pp, 3.8MB) U.S. EPA Policy Statement on Climate-Change Adaptation (PDF) (3pp, 55KB) Narayanan, Mysore. (2008). Hydrology, Water Scarcity and Market Economics. 68th AGU International Conference. Eos Transactions: American Geophysical Union, Vol. 89, No. 53, Fall Meeting Supplement, 2009. H11E - 0801. Postel, Sandra L. The Last Oasis: Facing Water Scarcity. New York: W. W. Norton and Company. 1997.

Writers, Athletes and Engineers Learn by Doing

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Narayanan, M.

2009-12-01

provided evidence-based reasoning and critical thinking. 6. He/She has suggested a time-line for completing the assignment. 7. The person has completed the required process in the alloted time-line. In this presentation the author stresses the importance of writing assignments in engineering disciplines. References: Barr, R. B., & Tagg, J. (1995, November/December). From teaching to learning: A new paradigm for undergraduate education. Change: The Magazine of Higher Education, 13-24. Cox, M. D., Grasha, A., & Richlin, L. (1997, March). Town meeting. Between teaching model and learning model: Adapting and adopting bit by bit. Paper presented at the ninth annual Lilly Conference on College and University Teaching - West, Lake Arrowhead, CA. Narayanan, Mysore (2009). Assessment Based on the principles of Theodore Marchese. ASEE 116th Annual Conference and Exposition, Austin, TX. June 14-17, 2009. Paper # AC 2009-1532. Saxe, S. (1990, June). Peer influence and learning. Training and Development Journal, 42 (6), 50-53. Senge, P. M. (1990). The fifth discipline: The art and practice of the learning organization. New York: Currency Doubleday.

Classroom Assessment Techniques

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Narayanan, M.

2003-12-01

and the learner should be carefully observed and monitored. Forrest says that Student Portfolios, which document learning in more detail, seldom reveal how teaching contributes to students' progress. Cerbin further indicates that a course portfolio is essentially, a like a manuscript of scholarly work in progress. In this example, it is a work that explains what, how, and why students learn or do not learn in a course. In this paper, the author reports on a dozen techniques that could perhaps be used to document assessment of student learning. References : Cerbin, W. (1993). Fostering a culture of teaching as scholarship. The Teaching Professor, 7(3), 1-2. Edgerton, R., Hutchings, P., & Quinlan, P. (1991). The teaching portfolio: Capturing the scholarship in teaching. Washington, DC: American Association for Higher Education. Forrest, A. (1990). Time will tell: Portfolio-assisted assessment of general education. Washington, DC: American Association for Higher Education. Linn, R., Baker, E., & Dunbar, S. (1991). Complex, Performance-based Assessment: Expectations and Validation Criteria. Educational Researcher, 20 (8), 15-21. Narayanan, M. (2003). Assessment in Higher Education: Partnerships in Learning. Paper presented at the 23rd Annual Lilly Conference on College Teaching, Miami University, Oxford, OH. Seldin, P. (1991). The teaching portfolio. Bolton, MA: Anker. Young, C. O., Sr., & Young, L. H. (1999). Assessing Learning in Interactive Courses. Journal on Excellence in College Teaching, 10 (1), 63-76.

Autologous Bone Marrow Stem Cells in Spinal Cord Injury; Our Experience in Clinical Studies, Animal Studies, Obstacles faced and steps for future

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Ayyappan S

2010-01-01

ensured the delivery of a higher proportion of cells in the damaged area. It is possible that the cells injected intrathecally are carried along with the CSF to parts other than that damaged as well. This has been supported by study 2 when it was applied with scaffold. The injury model used in study 2 is a natural traumatic model and is more akin to real life than any other controlled spinal cord model that one could create in the lab. This study 2 which is still in process allows for the animal to live to its entire course enabling us to follow up the neurological recovery of the patient and on its death perform an autopsy to not only determine the cause of death but to also examine the fate of stem cells injected intralesionally. We hope to determine the percentage of stem cells remaining as stem cells and to determine the nature and magnitude of histopathological changes that might have taken place which facilitated /non facilitated the recovery in the study animalsCONCLUSION:It is understood from the study 1, that the factors determining outcome are multiple and includes the age of patients, level of injury, time interval between injury and ABMMC injection, dosage of stem cells injected and all these need to be evaluated in future studies. More studies are necessary to ascertain the efficacy. Safety of both intrathecal and intralesional injection with scaffold have been proven in this studies. Inclusion of larger number of cases with a long term follow up is necessary to know the efficacy of intralesional therapy with scaffolds References1.Abraham S, Manjunath S, Baskar S, Senthil Kumar R, Dedeepiya V, Terunuma H, Ravikumar R, Narayanan R, Selvan R ,Sankaranarayanan S, Jasper J, Parthiban JKBC, Arjundas D and Subramanniyan SR. Autologous Stem Cell Injections for Spinal Cord Injury - A multicentric Study with 6 month follow up of 108 patients 7th Annual Meeting of Japanese Society of Regenerative Medicine, Nagoya, Japan, 13 - 14 March 2008 2.Vaquero J, Zurita M, Oya S

Selected Abstracts of the 2nd Congress of joint European Neonatal Societies (jENS 2017; Venice (Italy; October 31-November 4, 2017; Session "Quality Improvement, Parents Centered Care"

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--- Various Authors

2017-10-01

, I. SadasivamABS 7. SATISFACTION LEVEL OF PARENTS OF NICU SERVICES PROVIDED AND CONNECTION WITH THEIR EDUCATIONAL ATTAINMENT • E. Papamichael, E. Polycarpou, M. TaliasABS 8. TWO YEAR NEURODEVELOPMENTAL FOLLOW UP DATA: MEETING METRICS VS DELIVERING QUALITY ASSESSMENTS • M. Parmar, F. Ceroni, S. Narayanan, N. MerchantABS 9. EVALUATION OF PARENTAL INFORMED CONSENT PROCEDURE IN NEONATAL INTENSIVE CARE UNIT • E. van ’t Verlaat, E. de Kort, I. Reiss, M. van Weissenbruch, S. SimonsABS 10. POSTPARTUM DEPRESSION, BONDING AND COPING STRATEGIES IN MOTHERS OF NEWBORNS ADMITTED TO THE NEONATAL UNIT • R. Porta, G. Lasheras, E. Capdevila, B. Farré-Sender, J.M. FarréABS 11. PARENTS’ EXPERIENCES OF ACTIVE PARTICIPATION DURING THE WARD ROUND IN A NEONATAL INTENSIVE CARE UNIT • L. Börjesson, T. StendahlABS 12. REDUCING THE WASTAGE OF PAEDIATRIC RED CELLS • C. Roehr, J. Staves, S. Hemmatpour, N. Mohanraj, S. PavordABS 13. ACCURATE DETECTION OF CEREBRO­SPI­NAL FLUID FROM THE TIP OF INJEQ IQ-NEEDLE™ IN PEDIATRIC LUMBAR PUNCTURE – PRE­LIMINARY RESULTS OF A CLINICAL STUDY • S. Halonen, J. Kari, O. Tammela, K. Kronström, V. EskolaABS 14. SUPPORTING THE PEER SUPPORTER • G. Thomson, M.-C. BalaamABS 15. ONLINE PARENT SATISFACTION SURVEY IS REPRESENTATIVE DESPITE LOW RESPONSE • J. de Boer, M. van DijkABS 16. INCIDENCE OF HYPOTHERMIA ASSOCIATED WITH BIRTH AND INTRAHOSPITAL TRANS­PORT OF NEWBORN INFANTS REQUIRING AD­MISSION TO A NICU – A QUANTITATIVE OBSERVATIONAL STUDY • V. Hansson, M. Hedin, A. Örtenstrand, M. VibergABS 17. CLINICAL DECISION SUPPORT SYSTEMS FOR NEONATAL CARE – AN UPDATED COCHRANE SYSTEMATIC REVIEW • K.Tan, P. Dear, S. NewellABS 18. THERMOREGULATION AND PHYSIOLOGICAL STABILIZATION BY SKIN-TO-SKIN CONTACT AT BIRTH IN PRETERM INFANTS • A. Linnér, B. Sundberg, B. Westrup, B. SkioldABS 19. CONSERVATIVE TREATMENT OF IATROGENIC PERFORATIONS CAUSED BY GASTRIC TUBES IN EXTREMELY LOW BIRTH WEIGHT INFANTS – EXPERIENCE OF A SINGLE CENTER �

PREFACE: Cell-substrate interactions Cell-substrate interactions

Science.gov (United States)

Gardel, Margaret; Schwarz, Ulrich

2010-05-01

system, is strongly modulated by mechanosensing on substrates of varying stiffness [21]. Mogilner and Rubinstein present a theoretical systems analysis for the shape of rapidly migrating keratocytes [22]. Saez et al show, with microfabricated pillar assays, how force is distributed within a layer of epithelial cells [23]. For three-dimensional tissue models, new techniques have to be developed to characterize the complex mechanics of hydrogels. Levental et al [24] and Kotlarchyk et al [25] approach this challenge with mechanical and optical methods, respectively. Narayanan et al combine experiments and continuum models to explore how chemo-mechanical interactions influence tumor growth [26]. References [1] Chen C S, Mrksich M, Huang S, Whitesides G M and Ingber D E 1997 Geometric control of cell life and death Science 276 1425 [2] Pelham R J Jr and Wang Y-L 1997 Cell locomotion and focal adhesions are regulated by substrate flexibility Proc. Natl. Acad. Sci. USA 94 13661 [3] Engler A J, Sen S, Sweeney H L and Discher D E 2006 Matrix elasticity directs stem cell lineage specification Cell 126 677-89 [4] Geiger B, Spatz J P and Bershadsky A D 2009 Environmental sensing through focal adhesions Nat. Rev. Mol. Cell Biol. 10 21 [5] Boettiger D and Wehrle-Haller B 2010 Integrin and glycocalyx mediated contributions to cell adhesion identified by single cell force spectroscopy J. Phys.: Condens. Matter 22 194101 [6] Chirasatitsin S and Engler A J 2010 Detecting cell-adhesive sites in extracellular matrix using force spectroscopy mapping J. Phys.: Condens. Matter 22 194102 [7] Scrimgeour J, Kodali V K, Kovari D T and Curtis J E 2010 Photobleaching-activated micropatterning on self-assembled monolayers J. Phys.: Condens. Matter 22 194103 [8] Stricker J, Sabass B, Schwarz U S and Gardel M L 2010 Optimization of traction force microscopy for micron-sized focal adhesions J. Phys.: Condens. Matter 22 194104 [9] Metzner C, Raupach C, Mierke C T and Fabry B 2010 Fluctuations of

EDITORIAL: Strongly correlated electron systems Strongly correlated electron systems

Science.gov (United States)

Ronning, Filip; Batista, Cristian

2011-03-01

-dependent Zeeman splitting in strontium ruthenate Emil J Rozbicki, James F Annett, Jean-René Souquet and Andrew P Mackenzie Thermodynamics of itinerant metamagnetic transitions A M Berridge Magnon-mediated pairing and isotope effect in iron-based superconductors Jiansheng Wu and Philip Phillips Nernst quantum oscillations in bulk semi-metals Zengwei Zhu, Huan Yang, Aritra Banerjee, Liam Malone, Benoît Fauqué and Kamran Behnia Signatures of a quantum Griffiths phase in a d-metal alloy close to its ferromagnetic quantum critical point Almut Schroeder, Sara Ubaid-Kassis and Thomas Vojta Influence of super-ohmic dissipation on a disordered quantum critical point Thomas Vojta, José A Hoyos, Priyanka Mohan and Rajesh Narayanan The van Hemmen-Kondo model for disordered cerium systems S G Magalhaes, F M Zimmer and B Coqblin Chemical pressure, dilution and disorder in the heavy fermion compounds Ce3 - xLaxPd20Si6 (x = 1/3, 2/3) H Winkler, K-A Lorenzer, S Laumann, J Custers, A Prokofiev and S Paschen Magnetism of fine particles of Kondo lattices, obtained by high-energy ball-milling E V Sampathkumaran, K Mukherjee, Kartik K Iyer, Niharika Mohapatra and Sitikantha D Das Heavy fermion scaling: uranium versus cerium and ytterbium compounds J M Lawrence, C H Wang, A D Christianson and E D Bauer Temperature dependence of hybridization gaps in metallic heavy-fermion systems Xiaodong Yang, Peter S Riseborough and Tomasz Durakiewicz Low-energy properties of the Kondo lattice model O Bodensiek, R Žitko, R Peters and T Pruschke Temperature dependence of the zero-bias anomaly in the Anderson-Hubbard model: insights from an ensemble of two-site systems R Wortis and W A Atkinson A charge density wave in the hidden order state of URu2Si2 Jung-Jung Su, Yonatan Dubi, Peter Wölfle and Alexander V Balatsky Field-induced suppression of the heavy-fermion state in YbRh2Si2 Gertrud Zwicknagl Discontinuous Hall coefficient at the quantum critical point in YbRh2Si2 Sven Friedemann, Niels Oeschler, Steffen

Selected Abstracts of the 1st Congress of joint European Neonatal Societies (jENS 2015; Budapest (Hungary; September 16-20, 2015; Session “Epidemiology”

Directory of Open Access Journals (Sweden)

Various Authors

2015-09-01

.L. Charkaluk, C. Arnaud, P.Y. AncelABS 18. PREMEDICATION FOR NON-EMERGENCY NEONATAL INTUBATIONS: SURVEY OF PRACTICE ACROSS UNITED KINGDOM • V. Rajamoorthy, P. Dobbs, N. Agarwal, C.S. Narayanan, N. MerchantABS 19. HEALTH-RELATED QUALITY OF LIFE IN VERY PRETERM CHILDREN ASSESSED AT SCHOOL AGE: COMPARISON BETWEEN THE CHILDREN’S AND PARENTS’ REPORTS • M. Cuttini, I. Croci, L. Herich, M. Carrozzi, V. Chiandotto, S. Vicari, M. RaponiABS 20. THE EPIDEMIOLOGY OF LISTERIOSIS DURING PREGNANCY IN NORTHERN ITALY • E. Amato, M. Gori, P. Huedo, M. PontelloABS 21. HEARING IMPAIRMENT IN PREMATURE NEWBORNS – ANALYSIS BASED ON THE NATIONAL HEARING SCREENING DATABASE • K. Wroblewska-Seniuk, P. Dabrowski, G. Greczka, J. MazelaABS 22. IS ROUTINE USE OF ANTIBIOTICS IN PRETERM INFANTS BORN BY ELECTIVE CAESAREAN SECTION (COLD SECTION WITH RESPIRATORY DISTRESS SYNDROME JUSTIFIABLE? • R. Onita, H. GowdaABS 23. CLEARING SERIOUS INFECTION: A QUALITY IMPROVEMENT INITIATIVE TO REDUCE NOSOCOMIAL INFECTION • C. Duncan, C. Mayes, J.S. CraigABS 24. VAGINAL UREAPLASMA PARVUM BUT NOT UREALYTICUM COLONIZATION AT 12 TO 14 WEEKS OF GESTATION IS SIGNIFICANTLY ASSOCIATED WITH PRETERM DELIVERY • J. Rittenschober-Boehm, D. Kasper, S. Schulz, B. Pimpel, T. Waldhoer, E. Hafner, G. Sliutz, A. Witt, A. BergerABS 25. RESPIRATORY OUTCOMES IN LATE AND MODERATELY PRETERM INFANTS: RESULTS FROM A POPULATION-BASED STUDY • S. Robinson, S.E. Seaton, R.J. Matthews, S. Johnson, E.S. Draper, B.N. Manktelow, L.K. Smith, N. Marlow, D.J. Field, E.M. BoyleABS 26. PERFLUOROALKYL ACID EXPOSURE AND INFANTILE COLIC: A STUDY IN THE DANISH NATIONAL BIRTH COHORT • C.C. Bach, I. Milidou, B.H. Bech, E.A. Nohr, C. Søndergaard, J. Olsen, T.B. HenriksenABS 27. NORMAL REFERENCE VALUES FOR UMBILICAL CORD ARTERIAL PH IN PRETERM AND TERM INFANTS • B. Skiöld, O. Stephansson, S. JohanssonABS 28. PREDICTORS OF HOSPITAL DISCHARGE IN A SWISS NATIONAL COHORT OF VERY PRETERM INFANTS • C. Rüegger, M. Adams, S. Schulzke, S. Wellmann

Selected Abstracts of the 1st Congress of joint European Neonatal Societies (jENS 2015; Budapest (Hungary; September 16-20, 2015; Session “Other”

Directory of Open Access Journals (Sweden)

Various Authors

2015-09-01

TOUCH TECHNIQUE IN NORTHERN IRELAND’S NEONATAL UNITS • C. Anderson, M. Hogan, C. Carville, U. TolandABS 56. INFLUENCE OF THE THECHNIQUE OF URINE SAMPLING OF URINALYSIS RESULT AND CONTAMINATION RATE IN NEONATAL PERIOD • M. Štimac, D. Kardum, M. Sipl, S. Pušeljić, V. MilasABS 57. SCREENING FOR CONGENITAL CYTOMEGALOVIRUS (CMV INFECTION - ARE WE GETTING IT RIGHT? • M. Parmar, S. Bhayat, P. Dobbs, A. Joshi, S. Parida, C.S. Narayanan, N. Merchant

EDITORIAL: Colloidal suspensions Colloidal suspensions

Science.gov (United States)

Petukhov, Andrei; Kegel, Willem; van Duijneveldt, Jeroen

2011-05-01

Colloid-polymer mixtures and depletion interactions Phase stability of a reversible supramolecular polymer solution mixed with nanospheres Remco Tuinier When depletion goes critical Roberto Piazza, Stefano Buzzaccaro, Alberto Parola and Jader Colombo Tuning the demixing of colloid-polymer systems through the dispersing solvent E A G Jamie, R P A Dullens and D G A L Aarts Polydispersity effects in colloid-polymer mixtures S M Liddle, T Narayanan and W C K Poon Colloidal dynamics and crystallization Crystallization and aging in hard-sphere glasses C Valeriani, E Sanz, E Zaccarelli, W C K Poon, M E Cates and P N Pusey Real-time monitoring of complex moduli from micro-rheology Taiki Yanagishima, Daan Frenkel, Jurij Kotar and Erika Eiser Brownian motion of a self-propelled particle B ten Hagen, S van Teeffelen and H Löwen Crystallization in suspensions of hard spheres: a Monte Carlo and molecular dynamics simulation study T Schilling, S Dorosz, H J Schöpe and G Opletal Structural signature of slow dynamics and dynamic heterogeneity in two-dimensional colloidal liquids: glassy structural order Takeshi Kawasaki and Hajime Tanaka

Selected Abstracts of the 2nd Congress of joint European Neonatal Societies (jENS 2017; Venice (Italy; October 31-November 4, 2017; Session "Neurology and Follow-up"

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--- Various Authors

2017-10-01

DYSPLASIA FOR NEUROLOGICAL IMPAIRMENT IN 2-YEARS-OLD VERY PRETERM INFANTS IS HIGHER WHEN DIAGNOSED AT 40 THAN AT 36 WEEKS’ POSTMENSTRUAL WEEKS • A.M. Malavolti, D. Bassler, R. Arlettaz-Mieth, G. Faldella, B. Latal, G. NatalucciABS 8. PSYCHOSOCIAL OUTCOME OF INFANTS WITH CONGENITAL MALFORMATIONS AFTER POSTNATAL SURGICAL REPAIR • N. Doberschuetz, A. Allendorf, R. Dewitz, B. Wittekindt, U. Rolle, R. SchloesserABS 9. THERAPEUTIC HYPOTHERMIA AND HEARING IMPAIRMENT: INCIDENCE AND ASSOCIATED FACTORS • M.P. Fitzgerald, G. Norman, C. Mc Garvey, A. Reynolds, M. King, B. HayesABS 10. PRETERM INFANTS 33-35 WEEKS’ GESTATION WITH SEVERE HYPOXIC-ISCHEMIC ENCEPHALOPATHY TREATED WITH HYPOTHERMIA DO NOT PRESENT MORE ORGAN DYSFUNCTION THAN TERM NEWBORNS • M. Alsina, A. Martin-Ancel, M. Leon, G. Arca, E. Perez, A. García-AlixABS 11. IMPACT OF ENVIRONMENTAL FACTORS ON MOTOR AND COGNITIVE PERFORMANCE OF LATE PRETERM INFANTS • M.M. Santos, C. Corsi, A.C. Campos, N.A.C.F. RochaABS 12. THROMBOCYTOPENIA IS ASSOCIATED WITH SEVERE RETINOPATHY OF PREMATURITY CLINICALLY; IN MICE PLATELET TRANSFUSION SUPPRESSES RETINOPATHY • P. Lundgren, R. Liegl, S. Klevebro, G. Hellgren, C. Löfqvist, C. Mannheimer, Y. Sun, Z.-J. Liu, M.C. Sola-Visner, B. Hallberg, L.E.H. Smith, A. HellströmABS 13. COGNITIVE AND BEHAVIORAL ASPECTS OF EXECUTIVE FUNCTIONING AT AGE 6.5 YEARS IN CHILDREN BORN EXTREMELY PRETERM: A SWEDISH NATIONAL PROSPECTIVE STUDY (EXPRESS • A. Farooqi, F. Serenius, M. Adamsson, M. Hafström, U. Åden, K. StjernqvistABS 14. EARLY AMPLITUDE INTEGRATED ELECTRO­ENCEPHALOGRAM AS A PREDICTOR OF BRAIN INJURY IN NEWBORNS WITH VERY LOW BIRTH WEIGHT: A COHORT STUDY • R.C. Silveira, L.V. Magalhaes, M.I. Winckler, J.A. Bragatti, R.S. ProcianoyABS 15. NEONATAL ADMISSIONS FOR HYPOXIC ISCHEMIC ENCEPHALOPATHY: WEEKEND AND OUT OF HOURS EFFECT • F. Ceroni, M. Parmar, S. Narayanan, N. MerchantABS 16. WHICH PARTS OF GROWTH SHOULD BE MONITORED FOR NEURODEVELOPMENT OF PRETERM INFANTS • I.G. Song, H