Sample records for nakahara emanuele vardaci

  1. Genetics Home Reference: Emanuel syndrome (United States)

    ... of Emanuel syndrome include an unusually small head ( microcephaly ), distinctive facial features, and a small lower jaw ( ... MedlinePlus Encyclopedia: Cleft Lip and Palate MedlinePlus Encyclopedia: Microcephaly MedlinePlus Encyclopedia: Preauricular Tag or Pit General Information ...

  2. Derivative 11;22 (Emanuel Syndrome: A Case Report and A Review

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    Madan Gopal Choudhary


    Full Text Available Emanuel syndrome (ES is a rare anomaly characterized by a distinctive phenotype, consisting of characteristic facial dysmorphism, microcephaly, severe mental retardation, developmental delay, renal anomalies, congenital cardiac defects, and genital anomalies in boys. Here, we report a male neonate, with the classical features of Emanuel syndrome.

  3. Emanuele Trevi e la teoria iniziatica della letteratura

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    Andrea Rondini


    In Emanuele Trevi’s work it is possible to trace an initiatory theory of literature, conceiving the literary text both as vector of transformation for the reader and as a repository of initiatic culture, providing access to the hidden truths of existence. The text appears as one of the last, if not the last, container of this primordial wisdom: central in the ancient society and religion, today such great code substantially seems to be lost. Trevi’s fellows are historians of religion (Schuré, Corbin, Eliade, narrators (Apuelio, Melville, Collodi, Woolf, Joyce, protagonists of trips (Artaud, philosophers and critics (Agamben, Zolla, Citati, Calasso, C. Campo. Trevi’s theory apparently moves beyond the perimeter of literature, recovering an anthropological di- mension of symbolic expression that also features, in a narrow hermeneutical circle, music and painting. Thus literature draws near to an experience of apprenticeship and a sacred rite.

  4. Emanuel Rádl, jeho pojetí filosofie a výchovy


    Vojtíšková, Michaela


    1 Abstract: Bachelor's thesis Emanuel Rádl, his conception of philosophy and education will follow work and ideas of Czech philosopher and biologist Emanuel Radl. I will study the basic titles of works Consolation of Philosophy and essays devoted to partial topics and to the problem of education in the new Czechoslovak state. The theme of the analysis will be how Rádl thoughts were admitted to the society and how its thinking is valued today. Keywords: philosophy, education, morality, history...

  5. Emanuel Rádl a náboženství


    Píša, Josef


    Diploma thesis "Emanuel Rádl and Religion" deals with Radl's philosophy of religion. Author tries to explain basic ideas of Radl's philosophy. He describe Radl's thoughts in motion. Author tries to defend it's recency for nowadays science and philosophy. The main topic of the thesis is Rádl's thoughts on Christianity and his refusal of oriental religions 'and phiIosophies. Rádl described dangerous tendencies in European thinking at the beginning of Twentieth Century. He predicted rise of raci...

  6. Emanuel Sendromu


    M, Kazandı; V, Turan; B, Zeybek; A, rgon


    35 yaşında daha önceden 1 aylık spontan abortusu bulunan ve miad sezaryen doğum ile 3300gr sağlıklı çocuğu olan hastada şimdiki gebeliğinde yapılan 2. düzey taramasında ; nukal foldda kalınlaşma, diafragma hernisi, komplet endokardial yastık defekti ve trunkus arteriosis saptanması üzerine amniosentez yapıldı ve gebelik sonlandırılmasına gidildi. Misoprostol 200mg 6x1 uygulandı. Yapılan genetik incelemede 47, .. , +der(22) t(11,22) (q25;q13) saptandı. Aileye yapılan kromozom analizinde an...

  7. Using the Emanuel et al. framework to assess ethical issues raised by a biomedical research ethics committee in South Africa. (United States)

    Tsoka-Gwegweni, Joyce M; Wassenaar, Douglas R


    The Emanuel, Wendler, and Grady framework was designed as a universal tool for use in many settings including developing countries. However, it is not known whether the work of African health research ethics committees (RECs) is compatible with this framework. The absence of any normative or empirical weighting of the eight principles within this framework suggests that different health RECs may raise some ethical issues more frequently than others when reviewing protocols. We used the Emanuel et al. framework to assess, code, and rank the most frequent ethical issues considered by a biomedical REC during review of research protocols for the years 2008 to 2012. We extracted data from the recorded minutes of a South African biomedical REC for the years 2008 to 2012, designed the data collection sheet according to the Emanuel et al. framework, and removed all identifiers during data processing and analysis. From the 98 protocols that we assessed, the most frequent issues that emerged were the informed consent, scientific validity, fair participant selection, and ongoing respect for participants. This study represents the first known attempt to analyze REC responses/minutes using the Emanuel et al. framework, and suggests that this framework may be useful in describing and categorizing the core activities of an REC. © The Author(s) 2014.

  8. Emanuele KANCEFF, "L’immagine della Sicilia nei resoconti di viaggio del Settecento. Tra classicità ed emozione romantica", 2015

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    Pino Menzio


    Full Text Available Emanuele KANCEFF, "L’immagine della Sicilia nei resoconti di viaggio del Settecento. Tra classicità ed emozione romantica", Scicli, Edizioni di storia e studi sociali, 2015 [Book Review

  9. Identity, memory and la diarchia di bronzo Commemorating Vittorio Emanuele II and Giuseppe Garibaldi in post-Risorgimento Venice

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    Laura Parker


    Full Text Available Identità, memoria e la diarchia di bronzo Una commemorazione di Vittorio Emanuele II e Giuseppe Garibaldi nella Venezia postrisorgimentale   Questo saggio tratta della collocazione di due monumenti nella città di Venezia, nella seconda metà dell’Ottocento. Dopo l’unificazione della penisola, il nuovo governo ha capito chiaramente la necessità di costruire un’identità nazionale nella quale si potessero riconoscere le cento città. L’erezione di monumenti e l’organizzazione di varie commemorazioni – che hanno celebrato i protagonisti e gli eventi più importanti del Risorgimento – sono stati usati per ‘fare gli italiani’ nell’ambito postrisorgimentale. In questo contesto, l’articolo esplora la commemorazione di Vittorio Emanuele II e Giuseppe Garibaldi nella città lagunare, e analizza se la fusione tra mito risorgimentale e storia locale sia effettivamente realizzata.

  10. Evaluación del Entomopatogeno Verticillium lecanii (Zimm Viegas En el control de la escama blanda Philephedra tuberculosa Nakahara & Gill en Guanábana (Anona muricata L. Evaluation of the entomopatogenic Verticillium lecanii (Zimm. Viega5 in the control of the soft scale Philephedra tuberculosa Nakahara & Gil! in the guanabana (Anona muricata

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    Cavallazi Gina


    Full Text Available Una de las alternativas del control de la escama blanda Philephedra tuberculosa Nakahara & Gillen el cultivo de la Guanábana (Anona muricata L., como parte del manejo integrado, la constituye el uso del hongo entomopatógeno Verticillium lecanii (Zimm. Viegas, el cual se consideracomo controlador natural. El presente estudio se realizó con el fin de evaluar la eficacia del entomopatógeno Verticillium lecanii, como agente controlador de esta escama. La evaluación de la eficacia del hongo entomopatógeno, aislado a partir de material coleccionado en campo,se realizó mediante ensayos bajo condiciones de laboratorio y de campo. La producción masiva del hongo estuvo a cargo de una casa especializada y productora,además del establecimiento de dosis para recomendar. La dosisde 1,8 x 107conidiaspor mililitro de suspensión resultó ser la más eficaz en el control de la escama. El análisisde los resultados permitió, de igual forma, determinar que los individuos pertenecientes al segundo  instar ninfal presentan la mayor susceptibilidad al ataque del hongo.One the alternatives in the control of the soft scale Phílephedra tuberculosa Nakahara & Gill in the crop of Guanabana (Anona murícata. within the integral management, is the enthomopathogenic fungus Vertícillium lecaníí (Zimm. Viegas, as a natural control of this scale. This study had as objective, to evaluate the efficacy of Vertícíllíum lecanií as control of this scale. The evaluation of the efficacy of the enthomopatogenic fungus, isolated from material colected in the crop, was done by means assays in laboratory and crop conditions. The masive production of the entomopatogenic fungus was done by a producer, moreover the establishment of a recomended dose (1,8 x 107 conidias/ml that resulted be the most effective in the control of the scale. The analysis of the results permited to determine that the individuals in the second nymphal instar, present most susceptibility to the

  11. Accuracy of Methotrexate Use in Rheumatoid Arthritis Patients in Emanuel Klampok Hospital based on Explicit Criteria

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    Rizki Puspitasari


    Full Text Available Methotrexate (MTX is the first line therapy for rheumatoid arthritis (RA as an antiinflammatory and immunosuppressant agent. The purpose of this study was to evaluate the use of MTX in patients with rheumatoid arthritis at Emanuel Klampok Hospital based on criteria, including the indication, process indicators, complication, and outcome indicators. The medical record from 13 inpatients and 27 outpatients who used MTX were compared with the criteria. The results of this study demonstrated that all of the patients had appropriately indications to use MTX. Patients with risk factors that lead to GI disorders, hepatotoxicity, and bone marrow toxicity were 35 patients, 19 patients, and 15 patients respectively. There were 32 patients used MTX with the correct dosage, meanwhile incorrect dosage was showed in 3 patients with ClCr 61–80 mL/minute, 2 patients with ClCr 51–60 mL/minute, 1 patient with ClCr 10–50 mL/minute, and 2 patients with SGPT >3 normal value. The interaction with NSAID was happened in 35 patients and the interaction with hepatotoxicity agents in 19 patients. Complication occurred in 7 patients with effects that occur were GI disorders and 1 patient with chirrosis. There were 10 patients with clinical complaints reduced and 2 patients with the better condition. Indication of use MTX had appropriately, but process indicators, complication, and outcome indicators still not appropriate.

  12. Nuovi documenti su Emanuele di Bonaiuto da Camerino, banchiere e uomo di cultura ebreo tra le Marche e la Toscana del XV secolo / New documents about the Jew Emanuele di Bonaiuto da Camerino, banker and intellectual between Marche and Toscana regions in the 15th Century

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    Mafalda Toniazzi


    Between the Middle and Modern Ages, Marche and Tuscany, and especially Camerino and Florence, were involved in a constant dialogue (supported by commercial and political reasons and by the movement of people and goods that has not been confined to the economics, but has also interested the cultural sphere as well. This paper intends to focus particularly on the figure of the Jew Emanuel of Bonaiuto da Camerino, a famous banker and a talented businessman, one of the protagonists of this trend, who was also a keen scholar, able to gather around him great personalities of the coeval culture (like Jehuda Messer Leon, Yochanan Alemanno and Ovadiah of Jehuda from Bertinoro, to collate an important library and acting, therefore, as an intermediary between the two regions.

  13. Variabilidade fenotípica na síndrome do cromossomo supernumerário der(22t(11;22 (síndrome de Emanuel Phenotypical variability in supernumerary chromosome der(22t(11;22 syndrome (Emanuel syndrome

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    Rafael Fabiano M. Rosa


    Full Text Available OBJETIVO: Relatar dois pacientes com a síndrome de Emanuel (SE ou cromossomo supernumerário der(22t(11;22, secundária a translocações balanceadas familiares, apresentando fenótipos distintos. DESCRIÇÃO DE CASO: O primeiro paciente é uma menina branca de cinco anos de idade, apresentando hipotonia, atraso no desenvolvimento neuropsicomotor, movimentos estereotipados, microcefalia, ptose palpebral, orelhas proeminentes, fossetas e apêndices pré-auriculares, e imperfuração anal. As avaliações adicionais identificaram hipoplasia cerebral e estenose da válvula pulmonar. Possuía história também de laringotraqueomalácia e fenda palatina. O segundo paciente é um menino branco de seis meses de idade com hipotonia, movimentos coreoatetóticos, déficit de crescimento, microcefalia, microssomia hemifacial, fenda palatina, microtia, apêndices pré-auriculares e polegares proximalmente implantados. A ecocardiografia demonstrou estenose da válvula pulmonar, comunicação interatrial e interventricular, persistência do canal arterial e da veia cava superior esquerda. A radiografia de tórax identificou uma costela cervical. O cariótipo por bandas GTG mostrou a presença, em ambos os pacientes, de um cromossomo adicional der(22t(11;22, secundário a uma translocação balanceada materna no primeiro caso e paterna no segundo caso. COMENTÁRIOS: Apesar de a primeira paciente apresentar achados frequentes da SE, o caso adicional representa a segunda descrição da literatura com um fenótipo de espectro óculo-aurículo-vertebral (EOAV. Assim, ambos salientam a variabilidade clínica observada na SE e a importância da avaliação cariotípica em indivíduos com fenótipo de EOAV.OBEJECTIVE: To report two patients with Emanuel syndrome (ES or supernumerary chromosome der(22t(11;22, secondary to familial balanced translocations, presenting distinct phenotypes. CASES DESCRIPTION: The first patient was a five-year-old white girl presenting

  14. Les « routes du jazz », ou portrait du jazz en nomade : mémoire sonore et voyage identitaire dans Jazz from the Haiku King de James A. Emanuel (1999

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    Nathalie Vincent-Arnaud


    Full Text Available Poète américain contemporain, auteur de nombreux recueils dont l’éclectisme souligne son goût pour le franchissement des frontières géographiques et culturelles, James A. Emanuel fait figure de passeur entre l’art poétique et l’art musical comme en témoigne sa collaboration étroite avec des musiciens de jazz depuis une quinzaine d’années. Décrivant volontiers son activité poétique récente comme « des ponts jetés entre musique et poésie », revendiquant la paternité du genre du « jazz and blues and gospel haiku » dont la pratique s’est affirmée et systématisée dans son recueil Jazz from the Haiku King paru en 1999, il paraît ainsi s’inscrire de plein droit dans la tradition des poètes jazz initiée par un Kerouac ou un Burroughs au cours de la période particulièrement riche dans ce domaine de la Beat Generation.Consacré à l’exploration de l’« anatomie du jazz » à travers l’évocation d’une myriade de figures du jazz, du gospel et du blues – de Louis Armstrong à Sonny Rollins en passant par Cab Calloway, Ray Charles et Mahalia Jackson – le recueil est avant tout conçu comme le parcours de reconnaissance d’une mémoire culturelle. Au fil de ces « routes du jazz » – autoroutes soigneusement balisées ou chemins de traverse plus obscurs – qu’il met en scène, se trouvent peu à peu dévoilées les diverses facettes de la tension omniprésente entre la mémoire spécifique d’un peuple et l’élargissement à l’universel d’un art complexe qui fait résonner la symbiose de divers modes d’expression identitaire.Le présent article a pour but de montrer comment ces poèmes, au carrefour du linguistique et du musical, tissent une toile de fond identitaire des plus foisonnantes qui, œuvrant à la redéfinition d’un genre, confère à ce dernier de nouveaux et féconds points de résonance.

  15. Emanuel Lévinas a židovství

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    Petr Sláma


    Full Text Available This survey examines the Jewish inspiration of the work of Emmanuel Levinas. This inspiration has been long recognized explicitly in his Talmudic expositions that have appeared since the sixties. However, also the two central works of Levinas’s philosophical and ethical endeavour, his Totality and infinity (1961 and his Otherwise than being (1973, even thou arguing philosophically, do in their deep structure deal with the central concepts of the Bible, namely the utmost authority of Biblical prohibitions and the peculiar Hebrew idiom hinneni defining personality as the one who provide him- or herself to the Other.

  16. OrthoImagery Submission for Emanuel County, GA (United States)

    Federal Emergency Management Agency, Department of Homeland Security — NAIP imagery is available for distribution within 60 days of the end of a flying season and is intended to provide current information of agricultural conditions in...

  17. Emanuel Chalupný a Ferdinand Peroutka o J.A. Komenském

    Czech Academy of Sciences Publication Activity Database

    Beneš, Jiří


    Roč. 30, 63-64 (2000), s. 171-176 ISSN 0323-2220. [Obraz Jana Amose Komenského ve 20. století. Věda-mýtus-ideologie /22./. Uherský Brod, 07.10.1999-08.10.1999] Institutional research plan: CEZ:AV0Z9009908 Keywords : Comeniology Subject RIV: AA - Philosophy ; Religion


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    Dmitrij Samojlov


    Full Text Available This article discusses the influence of Kant’s ethics on philosophy of S. Gessen and the attempt of the latter to overcome the formalism of Kant’s moral teaching. It is to be noted, that although Gessen made much use of the achievements inherent in Kant’s ethics, he nevertheless came to the conclusion that the founder of the critical school in philosophy did not have the last word when it came to questions of morality. The Russian neo-Kantian philosopher thought Kant’s concept of ethical duty to constitute only one level of morality. Gessen went much further - reaching out to the essence of a higher order, that of love as the gift of grace

  19. Floodplain Mapping or Redelineation Submission for Emanuel County GA MapMod08 (United States)

    Federal Emergency Management Agency, Department of Homeland Security — The Floodplain Mapping/Redelineation study deliverables depict and quantify the flood risks for the study area. The primary risk classifications used are the...

  20. Erratum to Surface‐wave green’s tensors in the near field (United States)

    Haney, Matthew M.; Hisashi Nakahara,


    Haney and Nakahara (2014) derived expressions for surface‐wave Green’s tensors that included near‐field behavior. Building on the result for a force source, Haney and Nakahara (2014) further derived expressions for a general point moment tensor source using the exact Green’s tensors. However, it has come to our attention that, although the Green’s tensors were correct, the resulting expressions for a general point moment tensor source were missing some terms. In this erratum, we provide updated expressions with these missing terms. The inclusion of the missing terms changes the example given in Haney and Nakahara (2014).

  1. Memorias Conferencia Internacional IEEE Mexico 1971, Sobre Sistemas, Redes Y Computadoras. Volumen I and Volumen II. (Proceedings of International Conference of IEEE Concerning Systems, Networks, and Computers. Volume I and Volume II. (United States)

    Concheiro, A. Alonso, Ed.; And Others

    The following papers in English from this international conference may be of particular interest to those in the field of education. T. Nakahara, A. Tsukamota, and M. Matsumoto describe a computer-aided design technique for an economical urban cable television system. W. D. Wasson and R. K. Chitkara outline a recognition scheme based on analysis…

  2. Human Injury Criteria for Underwater Blasts (United States)


    further underscored the need for this new guideline based on injury data. Conference Name: Personal Armour Systems Symposium Conference Date...29.  Cole, R., Underwater Explosion. (Dover Publications, Inc ., New York, N.Y., 1948) 30.  Nakahara, M., Nagayama, K, Mori, Y, Japanese Journal...Abstract of the Undersea and Hyperbaric Medical Society, Inc . Annual Scientific Meeting, (1976).

  3. Publisher Correction

    DEFF Research Database (Denmark)

    Turcot, Valérie; Lu, Yingchang; Highland, Heather M


    In the published version of this paper, the name of author Emanuele Di Angelantonio was misspelled. This error has now been corrected in the HTML and PDF versions of the article.......In the published version of this paper, the name of author Emanuele Di Angelantonio was misspelled. This error has now been corrected in the HTML and PDF versions of the article....

  4. Pulverizing Portraits

    DEFF Research Database (Denmark)

    Elias, Camelia

    Pulverizing Portraits provides the first book-length study of contemporary American poet Lynn Emanuel. Emanuel's poetry is significant because it situates itself in relation to current debates about the state of poetry, creative writing in the academia, and the importance of drawing on interdisci......Pulverizing Portraits provides the first book-length study of contemporary American poet Lynn Emanuel. Emanuel's poetry is significant because it situates itself in relation to current debates about the state of poetry, creative writing in the academia, and the importance of drawing...... been increasingly concerned with poetry as a tool for cultural criticism which constantly redefines our poetic discourse. Elias traces the power of Emanuel's writing and looks at her subtleties in combining intrinsic and formal constraints in poetry with extrinsic and socio-historical methodologies...

  5. Two new species of Euptychia Hübner, 1818 from the upper Amazon basin (Lepidoptera, Nymphalidae, Satyrinae). (United States)

    Neild, Andrew F E; Nakahara, Shinichi; Zacca, Thamara; Fratello, Steven; Lamas, Gerardo; Le Crom, Jean-François; Dolibaina, Diego R; Dias, Fernando M S; Casagrande, Mirna M; Mielke, Olaf H H; Espeland, Marianne


    Two new species of Euptychia Hübner, 1818 are described from the upper Amazon basin: Euptychia attenboroughi Neild, Nakahara, Fratello & Le Crom, sp. n. (type locality: Amazonas, Venezuela), and Euptychia sophiae Zacca, Nakahara, Dolibaina & Dias, sp. n. (type locality: Acre, Brazil). Their unusual facies prompted molecular and phylogenetic analyses of one of the species resulting in support for their classification in monophyletic Euptychia. Diagnostic characters for the two species are presented based on wing morphology, wing pattern, presence of androconial patches on the hindwing, and genitalia. Our results indicate that the projection of the tegumen above the uncus, previously considered a synapomorphy for Euptychia, is not shared by all species in the genus. The adults and their genitalia are documented, and distribution data and a map are provided.

  6. Disease: H01790 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available ome caused by a parental balanced translocation between chromosomes 11 and 22. Chromosomal abnormality; Deve...lopmental disorder ... In more than 99% of cases, one of the parents of a proband with Emanuel syndrome is a balance

  7. Case Series and Review Deepti Saxena, Priyanka Srivastava, Moni

    Indian Academy of Sciences (India)


    Emanuel syndrome is characterized by severe intellectual disability, microcephaly, ... GRch 37: Feb 2009 (hg 19) human genome version was used to annotate ... He had mild facial asymmetry with the hypoplasia of the right side of the face.


    African Journals Online (AJOL)


    Nuovomondo (2006) di Emanuele Crialese condividono ben poco: corrono quasi settanta ... variazioni di significato. Qui lo si vuole utilizzare nel senso ormai classico a esso dato dalla ... Il realismo è, infatti, alla base delle due pellicole, ma il ...

  9. Effect of an electrolyte salt dissolving in polysiloxane-based electrolyte on passive film formation on a graphite electrode (United States)

    Nakahara, Hiroshi; Nutt, Steven

    Electrochemical impedance spectroscopy (EIS) was performed during the first charge of a graphite/lithium metal test cell to determine the effect of an electrolyte salt on passive film formation in a polysiloxane-based electrolyte. The graphite electrode was separated from the lithium metal electrode by a porous polyethylene membrane immersed in a polysiloxane-based electrolyte with the dissolved lithium bis(oxalato) borate (LiBOB) or lithium bis(trifluoromethanesulfonyl) imide (LiTFSI). In case of LiTFSI, the conductivity of system decreased at 1.2 V. In contrast, for the case of LiBOB, the conductivity decreased at 1.7 V. The magnitudes of charge transfer resistance and film resistance for LiTFSI were smaller than that for LiBOB. Passive films on highly oriented pyrolytic graphite (HOPG) after charging (lithiating) in polysiloxane-based electrolyte were inspected microscopically. Gel-like film and island-like films were observed for LiBOB [H. Nakahara, A. Masias, S.Y. Yoon, T. Koike, K. Takeya, Proceedings of the 41st Power Sources Conference, vol. 165, Philadelphia, June 14-17, 2004; H. Nakahara, S.Y. Yoon, T. Piao, S. Nutt, F. Mansfeld, J. Power Sources, in press; H. Nakahara, S.Y. Yoon, S. Nutt, J. Power Sources, in press]. However, for LiTFSI, there was sludge accumulation on the HOPG surface. Compositional analysis revealed the presence of silicon on both HOPG specimens with LiBOB and with LiTFSI. The electrolyte salt dissolved in the polysiloxane-based electrolyte changed the electrochemical and morphological nature of passive films on graphite electrode.

  10. Spectrophotometric activity microassay for pure and recombinant cytochrome P450-type nitric oxide reductase

    CSIR Research Space (South Africa)

    Garny, S


    Full Text Available spectrophotometric quantification of NADH [19]. Kaya et al. (2004) [19] demonstrated the linearly proportional relationship between the oxidation of NADH to NAD+, with the release of NO from NOC-5, but did not develop a kinetic assay for NOR activity using... this principle, the primary aim of this study. Nakahara et al. (1993) [10] determined the stoichiometry of NO reduction by NOR as 2:1:1 for NO:NADH:N2O. Therefore, for each NADH oxidized to NAD+, two molecules of NO are converted to N2O (refer Equation 1). 2...

  11. A Potentially Endangered New Species of Euptychia Hübner, 1818 (Lepidoptera: Nymphalidae: Satyrinae) from the Atlantic Coastal Forest of Brazil. (United States)

    Nakahara, S; Barbosa, E P; Freitas, A V L


    A new satyrine species in the subtribe Euptychiina, Euptychia atlantica Nakahara & Freitas sp. nov., is described from the Atlantic coastal forest of Brazil. Based on the existing museum specimens, E. atlantica sp. nov. is known from the coastal montane forests of Rio de Janeiro to south Bahia, a unique biogeographical region which is undergoing rapid degradation. Illustrations of adults and their genitalia, as well as a distribution map, are provided herein, in addition to a discussion of the relationships and conservation status of the new species.

  12. La differenza tra il discorso filosofico di Severino e quello di Cacciari

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    Davide Grossi


    Full Text Available The aim of this paper is to illustrate the difference between Emanuele Severino’s philosophical discourse and that of Massimo Cacciari by analyzing those fundamental concepts – such as “Destino”, “Elenchos” and the Principle of non-contradiction (PDNC – which are the core of their philosophies. We also propose this essay as an introduction to the complex interview with Emanuele Severino, also published on this issue, since it investigate the same range of philosophical themes.

  13. Konverze a rekonverze Emanuela Haunera v období fin de siècle


    Semsch, Alžběta


    The goal of the final thesis Emanuel Hauner's conversion and reconversion at the fin de siècle is to introduce and to interpret Emanuel Hauner's major poetic works, which have been so far neglected by the Czech literary history. My goal was to analyze the reasons of refusal of his works by both readers and critics. To make this analysis precise, it was necessary to take a close look at two phenomena appearing in Hauner's work: stylization and epigonism. The second major goal of this thesis wa...

  14. Universalidad de la computación cuántica geométrica modelo de tres estados Universalidad de la computación cuántica geométrica: modelo de tres estados

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    Andrés Sicard


    Full Text Available El modelo de tres estados es un modelo de computación cuántica geométrica. Se ilustra que éste es un modelo de computación cuántica universal, con base en el trabajo desarrollado por Niskanen, Nakahara y Salomaa [16]. Las universalidades U(2 y U(2n≥ 1 del modelo se obtienen a partir de la construcción de las compuertas de rotación Rx(α y R(α, y de las compuertas de Hadamard H y de fase B(η, respectivamente. Para cada compuerta, se presenta explícitamente el operador de holonomía ΓAy(γ y el ciclo γ sobre el cual es construída.The three state model is a geometric quantum computation model. We show that this one is an universal quantum computation model, with base in the work developed by Niskanen, Nakahara and Salomaa [16]. The U(2 and U(2n≥1 universalities are obtained from the construction of the rotations gates Rx(α and Ry(α, and the Hadamard gate H and the phase gates B(η, respectively. For every quantum gate, we explicitly show the holonomy operator ΓA(γ and the loop γ on which this is built.

  15. Shock wave dynamics derivatives and related topics

    CERN Document Server

    Emanuel, George


    "...this monograph develops an esoteric niche within shock wave theory. …treats shock waves from an analytical approach assuming perfect gas. Emanuel has made significant contributions to the theory of shock waves and has selected a number of topics that reflect those contributions."-Shock Waves, 2013.

  16. Plaadid / Heili Vaus-Tamm

    Index Scriptorium Estoniae

    Vaus-Tamm, Heili, 1961-


    Uutest plaatidest Keith Jarret/Gary Peacock/Jack DeJohnette "Up for it", Wladislaw Szpilman "The original recordings of the pianist", Emanuel Ax "Haydn Piano Sonatas", Ravi Coltrane "Mad 6", Guano Apes "Walking On A Thin Line", Will Young "From Now On", Janis Joplin "The Essential"

  17. Het die reformasie die leer gered en aanbidding verloor? | Spoelstra ...

    African Journals Online (AJOL)

    Little information is available on the relation between doctrine and liturgy during and after the Reformation. The concept “doctrine” relates to what is, since Emanuel Kant, labelled as theory and “liturgy” refers to practice as if these concepts were not related. This article investigates the validity of this perception. It asserts that ...

  18. The modal-epistemic argument for the existence of God is flawed

    NARCIS (Netherlands)

    S. Wintein (Stefan)


    textabstractIn a recent article, Emanuel Rutten has presented a novel argument for the existence of God, defined as a personal being that is the first cause of reality. An interesting feature of the argument, which caused quite a stir, is that it does not fall within any of the traditional

  19. Süvamuusika / Brigitta Davidjants

    Index Scriptorium Estoniae

    Davidjants, Brigitta, 1983-


    Uutest heliplaatidest Nikolaus Harnoncourt "Handel: Messiah", Nikolaj Znaider "Beethoven, Mendelssohn: Violin Concertos", Evgeni Kissin "Scriabin, Medtener, Stravinsky", Glenn Kotche "Mobile", Emanuel Ax "Chopin: Ballades, Scherzos & Mazurkas", Yefim Bronfman, Zurich Tonhalle Orchestra "Beethoven: Piano Concertos 3&4", Roger Waters "Ca Ira"

  20. Molecular Mechanisms and Diagnosis of Chromosome 22q11.2 Rearrangements (United States)

    Emanuel, Beverly S.


    Several recurrent, constitutional genomic disorders are present on chromosome 22q. These include the translocations and deletions associated with DiGeorge and velocardiofacial syndrome and the translocations that give rise to the recurrent t(11;22) supernumerary der(22) syndrome (Emanuel syndrome). The rearrangement breakpoints on 22q cluster…

  1. Studies on the distribution of gelatinous zooplankton in the ...

    African Journals Online (AJOL)


    boundary to the system (Agenbag and Shannon 1988,. Largier and Boyd 2001), it is not considered to have a profound influence on the specific composition of regional zooplankton (Gibbons et al. 1995, Gibbons and Thibault-Botha 2002, but see Barange et al. 1992,. Emanuel et al. 1992). Indeed, it has been suggested.

  2. Interview til debat

    DEFF Research Database (Denmark)

    Larsen, Tobias Boelt


    Artiklen beskæftiger sig med, hvordan journalist Martin Krasnik med sine interviewteknikker bryder med interviewformatet, som vi kender det, samt hvilke konsekvenser disse brud kan have. På baggrund af blandt andre John Heritage og Steven Clayman samt Emanuel Schegloffs undersøgelser af, hvordan ...

  3. Representation of monsoon intraseasonal oscillations in regional climate model: sensitivity to convective physics

    KAUST Repository

    Umakanth, U.; Kesarkar, Amit P.; Attada, Raju; Vijaya Bhaskar Rao, S.


    combinations of Grell (G) and Emanuel (E) cumulus schemes namely, RegCM-EG, RegCM-EE and RegCM-GE have been used. The model is initialized at 1st January, 2000 for a 13-year continuous simulation at a spatial resolution of 50 km. The models reasonably simulate

  4. 78 FR 48773 - Quarterly Publication of Individuals, Who Have Chosen To Expatriate, as Required by Section 6039G (United States)



  5. Grand Strategy: Contending Contemporary Analyst Views and Implications for the U.S. Navy (United States)


    New York: Alfred A. Knopf, 1967). 41 Charles Glaser, “Realists as Optimists: Cooperation as Self-Help,” International Security 19, no. 3, Winter...oriented towards addressing transnational challenges and 62 On security communities, see, e.g., Emanuel Adler

  6. Science, Technology, and the Quest for International Influence (United States)


    Alfred T. Mahan as one of the most important attributes supporting a state‘s claim to hegemony. Even after the rise of aviation, nuclear weapons, and...International Cooperation: The Impact of Protest on U.S. Arms Control Policy (Cambridge, UK: Cambridge University Press, 1998); Emanuel Adler , Communitarian

  7. Kant and Swedenborg

    DEFF Research Database (Denmark)

    Mebus, Andreas Nozic Lindgren


    It is commonly known that Hume played a major role in forming Kant's mature philosophy. But it is lesser known that Kant himself prior to his encounter with Hume, had a pivotal encounter with the Swedish mathematician and mysticist Emanuel Swedenborg. Thus this article will explore the nature...

  8. The Ethical Foundation of Critical Pedagogy in Contemporary Academia: (Self)-Reflection and Complicity in the Process of Teaching (United States)

    Rabikowska, Marta


    In this paper an ethical approach to educational methodology is discussed in relation to the philosophies of Emanuel Levinas and Robert Cox. Cox's anti-essentialist understanding of historical materialism and Levinas' metaphysical idealism are applied to an analysis of the (self)-reflective methods required today in Higher Education in the UK,…

  9. Bobby Few

    Directory of Open Access Journals (Sweden)

    James A. Emanuel


    Full Text Available  “I love you ALL.” Pain--from his bandaged thumb--said this,then music, his kiss. “My piano aches.”Voiced, old wounds made him look thintill his J-A-AZ jumped in.Copyright © 2008 by James A. Emanuel. All rights reserved.

  10. Veneetsias võitis Hiina üllataja

    Index Scriptorium Estoniae


    Veneetsia filmifestivali parima filmi peaauhind Kuldlõvi läks Hiina režissööri Jia Zhang-Ke filmile "Vaikelu" ("Dong"). Hõbelõvi said Alain Resnais' "Isiklikud hirmud avalikes kohtades" ("Coeurs") ja Emanuele Crialese "Kuldne uks" ("Nuodomondo"). Parima näitleja Coppa Volpi said Helen Mirren ja Ben Affleck

  11. Journal of Genetics | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Emanuel syndrome is caused due to an additional derivative chromosome 22 and is characterized by severe intellectual disability, microcephaly, failure to thrive, preauricular tags or pits, ear anomalies, cleft or high-arched palate, micrognathia, kidney abnormalities, congenital heart defects and genital abnormalities in ...

  12. Výběrová edice vzájemné korespondence Emanuela Chalupného a Karla Kramáře

    Czech Academy of Sciences Publication Activity Database

    Bílek, Jan; Quagliatová, Vlasta


    Roč. 17, Suppl. 2 (2009), s. 367-383 ISSN 1210-6860. [Karel Kramář (1860-1937). Praha, 31.10.2007-02.11.2007] Institutional research plan: CEZ:AV0Z70900502 Keywords : Kramář, Karel * Chalupný, Emanuel Subject RIV: AB - History

  13. 77 FR 41668 - Standard Instrument Approach Procedures, and Takeoff Minimums and Obstacle Departure Procedures... (United States)


    ... Obstacle DP, Amdt 2 Swainsboro, GA, Emanuel County, VOR/DME-A, Amdt 3, CANCELED Tifton, GA, Henry Tift... Minimums and Obstacle DP, Amdt 1 Pensacola, FL, Pensacola Gulf Coast Rgnl, VOR RWY 8, Amdt 4 Augusta, GA, Augusta Rgnl at Bush Field, ILS OR LOC RWY 17, Amdt 9 Augusta, GA, Augusta Rgnl at Bush Field, ILS OR LOC...

  14. Transgressie of transformatie?

    NARCIS (Netherlands)

    Verbrugge, A.M.


    At the end of his review of my latest book Staat van verwarring. Het offer van liefde, Emanuel Rutten poses some critical remarks in regards to my interpretation of eros. In my response, I will show that Rutten neglects several central motives in my understanding of the relationship between eros and

  15. Demonstration of the Trauma Nurses Talk Tough seat belt diversion program in North Carolina. (United States)


    Trauma Nurses Talk Tough is a seat belt diversion program originally developed at the Legacy Emanuel Hospital in Portland, Oregon, in 1988. Attendance at the course is a condition for a one-time dismissal of a seat belt citation without fine or court...

  16. 78 FR 22596 - Qualification of Drivers; Exemption Applications; Vision (United States)


    ...) Wesley J. Jenkins (IL) Francisco J. Jimenez (TX) Christopher J. Kane (VT) Kenneth C. Keil (CA) Melvin A. Kleman (OH) Michael Lafferty (ID) Roosevelt Lawson (AL) Eugene R. Lydick (VA) Emanuel N. Malone (VA.... Riendeau (ND) James A. Smith (WA) Clarence L. Swann, Jr. (AL) Michael G. Trueblood (IL) Donald A. Uplinger...

  17. Comparison between neurostimulation techniques repetitive transcranial magnetic stimulation vs electroconvulsive therapy for the treatment of resistant depression: patient preference and cost-effectiveness


    Magnezi, Racheli; Aminov, Emanuel; Shmuel, Dikla; Dreifuss, Merav; Dannon, Pinhas


    Racheli Magnezi,1 Emanuel Aminov,1 Dikla Shmuel,2 Merav Dreifuss,1 Pinhas Dannon1,2 1Public Health and Health Systems Management Program, Department of Management, Bar-Ilan University, Ramat Gan, 2Beer Yaakov Mental Health Center affiliated to Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel Objectives: Major depressive disorder (MDD) is a common disorder, widely distributed in the population, and is often associated with severe symptoms and functional impairment. It has be...

  18. Do behavioural insights matter for competition policy?


    CIRIOLO Emanuele


    Behavioural insights make use of behavioural economics and psychology to analyse how humans behave when adopting economic decisions. The use of behavioural insights to improve policy-making is becoming increasing popular all over the world. Pensions, taxes, unemployment, energy efficiency, adult education, charitable giving and, of course, competition policy have benefitted from the application of behavioural insights. Emanuele Ciriolo, from the European Commission Joint Research Centre, expl...

  19. Heartland Engineers: A Century of Superior Service 1907-2007 (United States)


    original position during high-speed flight. 1989 Fall of Berlin Wall 1991 Desert Storm 1997 Grand Opening American Jazz Museum 1991 Emanuel Cleaver...Company Design and Layout: Mary Hemmingway-Emrich, Black & White Graphic Design Research and Writing: Kimberly Langas Project Consultant: Paul Feldman, US...District Public Affairs Officer q 9 INTRODUCTION George Washington appointed the first engineer officers of the Army on June 16, 1775, during the American

  20. Clinical features and imaging findings in a case of Capgras syndrome


    Luca M; Bordone A; Luca A; Patti A; Sortino G; Calandra C


    Maria Luca,1 Andrea Bordone,1 Antonina Luca,2 Andrea Patti,1 Giuseppe Sortino,3 Carmela Calandra11Department of Medical and Surgery Specialties, Psychiatry Unit, 2Department GF Ingrassia, Section of Neuroscience, 3Department of Diagnostic Imaging, Radiology Unit, University Hospital Policlinico-Vittorio Emanuele, Catania, Sicily, ItalyAbstract: Capgras syndrome consists of the delusional belief that a person or persons have been replaced by doubles or impostors. It can occur in the context of...

  1. Taking a Quantum Leap in Cyber Deterrence (United States)


    frame an adversary‘s rationale and decision calculus. 82 Understanding a group‘s rationale helps frame a strategy for deterrence. Emanuel Adler leverage against America. 8586 Adler adds that when deterrence culture in this context is driven by religious and ethnic- nationalist beliefs...Path to the Quantum Computer. New York: Alfred A. Knopf, 2003. Kapur, S. Paul. "Deterring Nuclear Terrorists." In Complex Deterrence: Strategy in

  2. Perseverance of Power: The Relevancy of Nuclear Deterrence in the Future (United States)


    3 Patrick Morgan, "The Practice of Deterrence," in International Practices, ed. Emanuel Adler and Vincent Pouliot (Cambridge New York: Cambridge...Michael Dobbs, One Minute to Midnight : Kennedy, Khrushchev, and Castro on the Brink of Nuclear War, 1st ed. (New York: Alfred A. Knopf, 2008), 216...Monica, CA: RAND, 2012. Dobbs, Michael. One Minute to Midnight : Kennedy, Khrushchev, and Castro on the Brink of Nuclear War. 1st ed. New York: Alfred A

  3. Edgewood Biosensors Test Bed Hand-held and Man-Portable Edition (United States)


    CORPORATION, INC. Gunpowder, MD 21010-0068 Evan Skowronski TMG BIOSCIENCES Incline Village, NV 89451 September 2013 Approved for public release...Emanuel, Peter (ECBC); Rivers, Bryan; Schaffer, Eric (SAIC); and Skowronski, Evan ( TMG Biosciences) 5d. PROJECT NUMBER 5e. TASK NUMBER 5f. WORK...21010-0068 TMG Biosciences, 774 Mays Blvd. #10-455, Incline Village, NV 89451 8. PERFORMING ORGANIZATION REPORT NUMBER ECBC-TR-1201 9

  4. Effects of Acute and Subacute Oral Methylnitroguanidine (MeNQ) Exposure to Rats (Rattus norvegicus) (United States)


    white rabbits, however, it did cause mild conjunctival irritation [2]. Testing of MeNQ in a guinea pig indicated that MeNQ is a weak skin sensitizer... pig maximization test, where one guinea pig out of an unspecified number showed a sensitizing reaction. Additionally, MeNQ is potentially metabolized...assist in the identification of a specific product . ACKNOWLEDGEMENTS The authors gratefully acknowledge the support of Karl Kroeck and Emanuel Hignutt

  5. A tribute to Stanislao Cannizzaro, chemical informationist and photochemist. (United States)

    Roth, Heinz D


    Stanislao Cannizzaro is known widely for the Cannizzaro reaction, the "disproportionation" of benzaldehyde upon reaction with alkali, for his approach to teaching chemistry, "Sunto di un corso di filosofia chimica", which he presented at the Karlsruhe Congress of 1860, and for his work on the photochemistry of santonin. In Cannizzaro's laboratory two research associates, Giacomo Ciamician and Paul Silber, and a senior colleague, Emanuele Paternó, became acquainted with the basic methods of sunlight-inducd photochemistry.

  6. Exploring Jets from a Supermassive Black Hole (United States)

    Kohler, Susanna


    What are the feeding and burping habits of the supermassive black holes peppering the universe? In a new study, observations of one such monster reveal more about the behavior of its powerful jets.Beams from BehemothsAcross the universe, supermassive black holes of millions to billions of solar masses lie at the centers of galaxies, gobbling up surrounding material. But not all of the gas and dust that spirals in toward a black hole is ultimately swallowed! A large fraction of it can instead be flung out into space again, in the form of enormous, powerful jets that extend for thousands or even millions of light-years in opposite directions.M87, shown in this Hubble image, is a classic example of a nearby (55 million light-years distant) supermassive black hole with a visible, collimated jet. Its counter-jet isnt seen because relativistic effects make the receding jet appear less bright. [The Hubble Heritage Team (STScI/AURA) and NASA/ESA]What causes these outflows to be tightly beamed collimated in the form of jets, rather than sprayed out in all directions? Does the pressure of the ambient medium the surrounding gas and dust that the jet is injected into play an important role? In what regions do these jets accelerate and decelerate? There are many open questions that scientists hope to understand by studying some of the active black holes with jets that live closest to us.Eyes on a Nearby GiantIn a new study led by Satomi Nakahara (The Graduate University for Advanced Studies in Japan), a team of scientists has used multifrequency Very Long Baseline Array (VLBA) and Very Long Array (VLA) images to explore jets emitted from a galaxy just 100 million light-years away: NGC 4261.This galaxys (relatively) close distance as well as the fact that were viewing it largely from the side, so we can clearly see both of its polar jets allows us to observe in detail the structure and intensity of its jets as a function of their distance from the black hole. Nakahara and

  7. Performance of Regional Climate Model in Simulating Monsoon Onset Over Indian Subcontinent (United States)

    Bhatla, R.; Mandal, B.; Verma, Shruti; Ghosh, Soumik; Mall, R. K.


    The performance of various Convective Parameterization Schemes (CPSs) of Regional Climate Model version 4.3 (RegCM-4.3) for simulation of onset phase of Indian summer monsoon (ISM) over Kerala was studied for the period of 2001-2010. The onset date and its associated spatial variation were simulated using RegCM-4.3 four core CPS, namely Kuo, Tiedtke, Emanuel and Grell; and with two mixed convection schemes Mix98 (Emanuel over land and Grell over ocean) and Mix99 (Grell over land and Emanuel over ocean) on the basis of criteria given by the India Meteorological Department (IMD) (Pai and Rajeevan in Indian summer monsoon onset: variability and prediction. National Climate Centre, India Meteorological Department, 2007). It has been found that out of six CPS, two schemes, namely Tiedtke and Mix99 simulated the onset date properly. The onset phase is characterized with several transition phases of atmosphere. Therefore, to study the thermal response or the effect of different sea surface temperature (SST), namely ERA interim (ERSST) and weekly optimal interpolation (OI_WK SST) on Indian summer monsoon, the role of two different types of SST has been used to investigate the simulated onset date. In addition, spatial atmospheric circulation pattern during onset phase were analyzed using reanalyze dataset of ERA Interim (EIN15) and National Oceanic and Atmospheric Administration (NOAA), respectively, for wind and outgoing long-wave radiation (OLR) pattern. Among the six convective schemes of RegCM-4.3 model, Tiedtke is in good agreement with actual onset dates and OI_WK SST forcing is better for simulating onset of ISM over Kerala.


    Directory of Open Access Journals (Sweden)



    Full Text Available In his comments on Mircea Vulcănescu. O microistorie a interbelicului românesc (Eikon, 2015, Emanuel Copilaş states that, regarding the cause of the far right radicalization manifested in the interwar Romania, I share the same historical explanation about fascism as Ernst Nolte. In this concise answer, I explain why this is an unsuitable comparison by summarizing the historiographical perspective I use in the cited volume. Nevertheless, Copilaş’s comments are reopening a debate about how to explain the Romanian fascism

  9. Assessing the decennial, reassessing the global

    DEFF Research Database (Denmark)

    Manners, Ian James


    in global politics by rethinking the nature of power and actorness in a globalizing, multilateralizing and multipolarizing era. To do this, the article assesses the past decade in terms of normative power engagement, internationalization and comparison. The article then argues that rethinking power...... and actorness involves reassessing global theory and pouvoir normatif in action. The article concludes by setting out three ways of developing the NPA in its second decade: macro-approach, meso-characterization and micro-analysis. Following the suggestion of Emanuel Adler, Barry Buzan and Tim Dunne, the article...

  10. Tõhusad tükid teismeliste poiste raamaturiiulis / Aidi Vallik

    Index Scriptorium Estoniae

    Vallik, Aidi, 1971-


    Tutvustus: Townsend, Sue. Salajane päevik. Tallinn : Tänapäev, 2002 ; Jacobsson, Anders, Olsson, Sören. Emanuel. Tallinn : Hotger, 2002 ; Brennan, Herbie. Haldjasõjad. Tallinn : Varrak, 2005 ; Paolini, Christopher. Eragon. Tallinn : Pegasus, 2005 ; Paolini, Christopher. Vanem. Tallinn : Pegasus, 2006 ; Vallik, Aidi. Narkohollo ehk Florose vabastamine. Tartu : Lugu-Loo, 2006 ; Schlüter, Andreas. Laste linn. Tallinn : Tormikiri, 2005 ; Schlüter, Andreas. Rööv. Tallinn : Tormikiri, 2005 ; Sachar, Lois. Augud. Tallinn : Draakon ja Kuu, 2005 ; Rannap, Jaan. Roheline kindlus. Tartu : Tiritamm, 2006 ; Henno, Sass. Mina olin siin. Tallinn : Eesti Päevalehe Kirjastus, 2005

  11. International Conference on the Physics of Electronic and Atomic Collisions. Participants List (16th), Held in New York, New York on 26 July-1 August 1989 (United States)



  12. Gozo Philatelic Society Newsletter : no. 47 : January-March 2012


    Gozo Philatelic Society


    Contents: GPS Diary by Antoine Vassallo - 12th Annual General Meeting by Anton V Said - 12th Annual General Meeting (15.01.2012) by Antoine Vassallo - The Annual Philatelic Exhibition by Anton V Said - [In the “Promoting Gozo Through Philately” series] Comino's Fortifications by Antoine Vassallo - [In the “Stamp terms used in PHILATELY” series] Nossi-Be or Noss Be to Nyassa by Emanuel Vella - Maltese Lizards (part 2) by Nathaniel Refalo - [In the “E & O not E” series] The 2003, Canada stamp f...

  13. Gozo Philatelic Society Newsletter : no. 53 : July-September 2013


    Gozo Philatelic Society


    Contents: GPS Diary by Antoine Vassallo - Is there money in the mail? Problems concerning the carriage of mail to and from Malta during the late nineteenth century by Michael Refalo - [In the “Stamp terms used in PHILATELY” series] Obock to Offpaper by Emanuel Vella - [In the “Philatelic Centennials” series] Australia is “born” 1913 by Antoine Vassallo - [In the “Not just Paper” series], Superman on stamps from Jersey by Antoine Vassallo - [In the “Malta overseas : local connections on foreig...

  14. Bimodal character of cyclone climatology in the Bay of Bengal modulated by monsoon seasonal cycle

    Digital Repository Service at National Institute of Oceanography (India)

    Li, Z.; Yu, W.; Li, T.; Murty, V.S.N.; Fredolin, T.

    (WSP). TCs draw intense scientific and social interest concerns due to the following three reasons. Firstly, they contribute importantly to the overall summer season rainfall in regions such as WNP. Secondly they play a key role in modulating.... 2005; Emanuel 2005; Landsea et al. 2006; Li et al. 2010). The BoB hosts the majority of North Indian Ocean (NIO) TCs. Statistical analysis reveals that there are a total of 150 TCs during the period of 1981-2009 in the NIO, among which about 2...

  15. Impact of tropical cyclones on the heat budget of the south Pacific Ocean

    Digital Repository Service at National Institute of Oceanography (India)

    Jullien, S.; Menkes, C.E.; Marchesiello, P.; Jourdain, N.C.; Lengaigne, M.; Koch-Larrouy, A.; Lefevre, J.; Vincent, E.M.; Faure, V.

    ; Withee and Johnson 1976; Pudov et al. 1979; McPhaden et al. 2008), which feeds back to them, moderating their intensity (Schade and Emanuel 1999; D’Asaro et al. 2007). Un- derstanding the surface heat balance associated with TCs is thus of major relevance... SST cooling asymmetry (in the Northern Hemisphere) is often ob- served (e.g., Pudov et al. 1979; McPhaden et al. 2008; Shay et al. 1992) and has been largely attributed to two phenomena. First, the wind stress asymmetry associated with TC translation...

  16. Partnership between the school of nursing and the hospital: supervisors' perspectives


    Martins, Cristina Araújo; Macedo, Ana Paula; Araújo, Odete; Oliveira, Cláudia; Braga, Maria de Fátima Dias; Gomes, Lisa Alves; Silva, Maria Augusta; Rosário, Rafaela


    Table of contents S1 Health literacy and health education in adolescence Catarina Cardoso Tom?s S2 The effect of a walking program on the quality of life and well-being of people with schizophrenia Emanuel Oliveira, D. Sousa, M. Uba-Chupel, G. Furtado, C. Rocha, A. Teixeira, P. Ferreira S3 Diagnosis and innovative treatments - the way to a better medical practice Celeste Alves S4 Simulation-based learning and how it is a high contribution Stefan Gisin S5 Formative research about acceptability...

  17. Resumen de tesis. Conoscenza e azione. La teoria delle intentiones nella Escuela de Salamanca


    Lacca, Emanuelle


    [ES] La tesis de doctorado de Emanuele Lacca, titulada Conoscenza e azione. La teoria delle intentiones nella Escuela de Salamanca (XV-XVI secolo), hecha en cotutela entre las universidades de Salamanca y de Cagliari (Italia) y defendida el 18 de abril de 2016, pretende reconstruir los conceptos de conocimiento y de intencionalidad, así como se desarrollan por algunas voces significativae de la Escuela de Salamanca, a partir de la recepción de la tradición tomista y de las inovaciónes del hum...

  18. A simple photometric factor in perceived depth order of bistable transparency patterns. (United States)

    Fukiage, Taiki; Oishi, Takeshi; Ikeuchi, Katsushi


    Previous studies on perceptual transparency defined the photometric condition in which perceived depth ordering between two surfaces becomes ambiguous. Even under this bistable transparency condition, it is known that depth-order perceptions are often biased toward one specific interpretation (Beck, Prazdny, & Ivry, 1984; Delogu, Fedorov, Belardinelli, & van Leeuwen, 2010; Kitaoka, 2005; Oyama & Nakahara, 1960). In this study, we examined what determines the perceived depth ordering for bistable transparency patterns using stimuli that simulated two partially overlapping disks resulting in four regions: a (background), b (portion of right disk), p (portion of left disk), and q (shared region). In contrast to the previous theory that proposed contributions of contrast against the background region (i.e., contrast at contour b/a and contrast at contour p/a) to perceived depth order in bistable transparency patterns, the present study demonstrated that contrast against the background region has little influence on perceived depth order compared with contrast against the shared region (i.e., contrast at contour b/q and contrast at contour p/q). In addition, we found that the perceived depth ordering is well predicted by a simpler model that takes into consideration only relative size of lightness difference against the shared region. Specifically, the probability that the left disk is perceived as being in front is proportional to (|b - q| - |p - q|) / (|b - q| + |p - q|) calculated based on lightness.

  19. Load leveling air conditioning technology development by unused energy high-level utilization. Summary of lectures given at the achievement report meeting; Miriyo energy kodo katsuyo fuka heijunka reidanbo gijutsu kaihatsu. Seika hokokukai koen yoshishu

    Energy Technology Data Exchange (ETDEWEB)



    This paper summarizes lectures given at the research and development achievement report meeting on load leveling air conditioning technologies utilizing unutilized energies at high levels. The lecture titled 'the current status and future problems in heat supply industries' given by the manager of the Heat Supply Industry Department at the Agency of Natural Resources and Energy explained the heat supply businesses in relation with global environment issues, electric power load leveling, and cogeneration. The lecture titled 'improvement of cities to energy saving type cities and district air conditioning systems' given by a construction official at the Ministry of Construction explained the guideline (draft) for introduction of district air conditioning systems as to their purpose, positioning, procedure for discussing the introduction, and procedure for its implementation as a business. The lecture titled 'the recent trend inside and outside the country around unutilized energies' given by Professor Tanazawa at the Tokyo University of Agriculture and Technology described the intensification of energy problems, environment problems, and the near future measures to be taken against these problems. The lecture titled 'summarization of the achievements in development of load leveling air conditioning technologies utilizing unutilized energies at high levels' given by Professor Nakahara at the Kanagawa University explained the summary of the achievements in research and development by themes. (NEDO)

  20. Chemically-induced liquid film migration with low lattice diffusivity relative to the migration rate in Mo-Ni-(W)

    International Nuclear Information System (INIS)

    Lee, K.R.


    This paper reports that when a 90Mo-10Ni alloy (by wt) liquid phase sintered at 1400 degrees C is heat-treated at 1400 degrees C after replacing the matrix with a melt of 44Ni-34Mo-22W (by wt), the liquid films between the grains migrate, leaving behind an Mo alloy enriched with W. The ratio of the lattice diffusivity of W in Mo, D, to the initial migration velocity, v. (D/v) is estimated to be between 0.03 and 0.18 angstrom. Hence it appears that there is no lattice diffusion of W ahead of the migrating liquid film, and is such a case the driving force has been suggested to be the chemical free energy. But the observed v is approximately same as that to be expected if the driving force is assumed to be diffusional coherency strain energy. Likewise, a previous study of den Broeder and Nakahara shows that the rate of chemically-induced grain boundary migration in Cu-Ni shows a smooth variation with temperature as D/v decreases from values much larger than the interatomic spacing to values much smaller with decreasing temperature. The coherency strain energy thus appears to be a general driving force for the migration even when the apparent diffusion length indicated by D/v is smaller than the interatomic spacing


    Borza, Liana Rada; Gavrilovici, Cristina; Stockman, René


    The present paper revisits the ethical models of patient--physician relationship from the perspective of patient autonomy and values. It seems that the four traditional models of physician--patient relationship proposed by Emanuel & Emanuel in 1992 closely link patient values and patient autonomy. On the other hand, their reinterpretation provided by Agarwal & Murinson twenty years later emphasizes the independent expression of values and autonomy in individual patients. Additionally, patient education has been assumed to join patient values and patient autonomy. Moreover, several authors have noted that, over the past few decades, patient autonomy has gradually replaced the paternalistic approach based on the premise that the physician knows what is best for the patient. Neither the paternalistic model of physician-patient relationship, nor the informative model is considered to be satisfactory, as the paternalistic model excludes patient values from decision making, while the informative model excludes physician values from decision making. However, the deliberative model of patient-physician interaction represents an adequate alternative to the two unsatisfactory approaches by promoting shared decision making between the physician and the patient. It has also been suggested that the deliberative model would be ideal for exercising patient autonomy in chronic care and that the ethical role of patient education would be to make the deliberative model applicable to chronic care. In this regard, studies have indicated that the use of decision support interventions might increase the deliberative capacity of chronic patients.

  2. The performance of RegCM4 over the Central America and Caribbean region using different cumulus parameterizations (United States)

    Martínez-Castro, Daniel; Vichot-Llano, Alejandro; Bezanilla-Morlot, Arnoldo; Centella-Artola, Abel; Campbell, Jayaka; Giorgi, Filippo; Viloria-Holguin, Cecilia C.


    A sensitivity study of the performance of the RegCM4 regional climate model driven by the ERA Interim reanalysis is conducted for the Central America and Caribbean region. A set of numerical experiments are completed using four configurations of the model, with a horizontal grid spacing of 25 km for a period of 6 years (1998-2003), using three of the convective parameterization schemes implemented in the model, the Emanuel scheme, the Grell over land-Emanuel over ocean scheme and two configurations of the Tiedtke scheme. The objective of the study is to investigate the ability of each configuration to reproduce different characteristics of the temperature, circulation and precipitation fields for the dry and rainy seasons. All schemes simulate the general temperature and precipitation patterns over land reasonably well, with relatively high correlations compared to observation datasets, though in specific regions there are positive or negative biases, greater in the rainy season. We also focus on some circulation features relevant for the region, such as the Caribbean low level jet and sea breeze circulations over islands, which are simulated by the model with varied performance across the different configurations. We find that no model configuration assessed is best performing for all the analysis criteria selected, but the Tiedtke configurations, which include the capability of tuning in particular the exchanges between cloud and environment air, provide the most balanced range of biases across variables, with no outstanding systematic bias emerging.

  3. A hitherto unknown edition of the Spanish Psalter by Abraham Usque (Ferrara 1554

    Directory of Open Access Journals (Sweden)

    Leoni, Aron di Leone


    Full Text Available The Biblioteca Nazionale Vittorio Emanuele in Roma owns a Psalter in Spanish published in 1554 by Abraham Usque. It is the matter of a hitherto unknown second edition of the Psalterium printed in Ferrara in 1553. From the «Prologo» we learn that Abraham Usque was not only a simple printer but also the editor and one of the translators of this book. He also stated to have worked at the translation of the Biblia en lengua Española (Ferrara 1553 together with eminent scholars.

    En la Biblioteca Nazionale Vittorio Emanuele de Roma se conserva un Salterio en español publicado en 1554 por Abraham Usque. Se trata de una segunda edición hasta ahora desconocida de su Psalterium impreso en Ferrara en 1553. Por su «Prologo» sabemos que Abraham Usque no actuó sólo como un mero impresor sino que también participó en la edición y fue uno de los traductores del libro. En dicho «Prologo» afirma asimismo que, junto con otros eminentes eruditos, había trabajado en la traducción de la Biblia en lengua Española (Ferrara 1553.

  4. "Professional Helper" or "Helping Professional?" The Patient-Physician Relationship in the Chronic Pain Setting, With Special Reference to the Current Opioid Debate. (United States)

    Bäckryd, Emmanuel


    There seems to be a strong cultural expectation among patients for effective pain relief. As a result, physicians often find themselves trying to bridge the gap between the chronic pain patient's expectations and harsh biomedical reality. The typology of Emanuel and Emanuel of four models for the patient-physician relationship is used in this article as a conceptual tool to examine the possible roles of physicians in the context of chronic noncancer pain. Their typology is reconceptualized as a "pathway" along which the physician is able to walk more or less far, starting from the "information" end of the path. The other end of the pathway is "caring deliberation." I then propose that, in pain medicine today, consumerism is a powerful incentive for physicians to stay at the information end of the spectrum. Against this background, I discuss the current opioid epidemic in the United States and the need for what has been called a new medical professionalism. I conclude by challenging educators involved in pain medicine continuing professional development to not only design adequate biomedical-educational programs, but also consider issues like professionalism, personal development, critical self-reflection, and the ethics of engaging in caring deliberation with chronic pain patients.

  5. How can tropical cyclones survive? (United States)

    Smedman, Ann-Sofi


    How can tropical cyclones survive? It is important for understanding the development of tropical cyclones to be able to quantify the exchange of enthalpy and momentum between air and water. Air-sea fluxes are often formulated as drag CD and enthalpy CK exchange coefficients. Emanuel, 1986, derived an expression for potential intensity that depends on local environment parameters and is proportional to the ratio of enthalpy and drag coefficients. This ratio should be larger than 0.75 for a cyclone to develop. There are no direct surface measurements of CK/ CD under hurricane conditions and extrapolation from most open-ocean measurements at 25 m/s gives values of CK/ CD0.75 is in accordance with Emanuel's prediction. The high CK values are observed during situations when there is a regime shift of the structure of turbulence in the boundary layer. From spectral analysis it was found that as the boundary layer approaches neutral stratification, smaller-scale eddies become increasingly important in the turbulent transport of humidity and sensible heat and thus enhance the exchange coefficient CK. This turbulence regime is called the UVCN regime and require high wind speed, small temperature difference between air and water, sufficiently strong wind gradients and growing sea condition ( Smedman et al., 2007, Sahlee et al., 2008). What is the difference between world oceans and enclosed seas? The answer is the waves. The wave field over the open oceans is swell dominated but in enclosed seas and coastal areas swell is restricted mainly to low wind speed conditions, and swell is short lived because of short distances to the shores. When swell is present the MABL will be dominated by large eddies of zi size creating weak gradients of wind, temperature and humidity and thus small scale eddies cannot be formed leading to reduced CK-values. However, during hurricane condition the waves are expected to be young, stratification is close to neutral and gradients are sufficiently

  6. Chemical equilibration in relativistic heavy ion collisions

    International Nuclear Information System (INIS)

    Brown, Gerald E.; Lee, Chang-Hwan; Rho, Mannque


    In the hadronic sector of relativistic heavy ion physics, the ρ<-2π reaction is the strongest one, strong enough to equilibrate the ρ with the pions throughout the region from chemical freezeout to thermal freezeout when free-particle interactions (with no medium-dependent effects) are employed. Above the chiral restoration temperature, only ρ's and π's are present, in that the chirally restored A1 is equivalent to the ρ and the mesons have an SU(4) symmetry, with no dependence on isospin and negligible dependence on spin. In the same sense the σ and π are 'equivalent' scalars. Thus the chirally restored ρ<-2π exhaust the interspecies transitions. We evaluate this reaction at Tc and find it to be much larger than below Tc, certainly strong enough to equilibrate the chirally restored mesons just above Tc. When emitted just below Tc the mesons remain in the Tc+ε freezeout distribution, at least in the chiral limit because of the Harada-Yamawaki 'vector manifestation' that requires that mesonic coupling constants go to zero (in the chiral limit) as T goes to Tc from below. Our estimates in the chiral limit give deviations in some particle ratios from the standard scenario (of equilibrium in the hadronic sector just below Tc) of about double those indicated experimentally. This may be due to the neglect of explicit chiral symmetry breaking in our estimates. We also show that the instanton molecules present above Tc are the giant multipole vibrations found by Asakawa, Hatsuda and Nakahara and of Wetzorke et al. in lattice gauge calculations. Thus, the matter formed by RHIC can equivalently be called: chirally restored mesons, instanton molecules, or giant collective vibrations. It is a strongly interacting liquid

  7. The role of the dorsoanterior striatum in implicit motivation: The case of the need for power

    Directory of Open Access Journals (Sweden)

    Oliver C Schultheiss


    Full Text Available Implicit motives like the need for power (nPower scale affective responses to need-specific rewards or punishments and thereby influence activity in motivational-brain structures. In this paper, we review evidence specifically supporting a role of the striatum in nPower. Individual differences in nPower predict (a enhanced implicit learning accuracy, but not speed, on serial-response tasks that are reinforced by power-related incentives (e.g., winning or losing a contest; dominant or submissive emotional expressions in behavioral studies and (b activation of the anterior caudate in response to dominant emotional expressions in brain imaging research. We interpret these findings on the basis of Hikosaka, Nakamura, Sakai, and Nakahara's (2002; Current Opinion in Neurobiology, 12(2, 217-222 model of central mechanisms of motor skill learning. The model assigns a critical role to the dorsoanterior striatum in dopamine-driven learning of spatial stimulus sequences. Based on this model, we suggest that the dorsoanterior striatum is the locus of nPower-dependent reinforcement. However, given the centrality of this structure in a wide range of motivational pursuits, we also propose that activity in the dorsoanterior striatum may not only reflect individual differences in nPower, but also in other implicit motives, like the need for achievement or the need for affiliation, provided that the proper incentives for these motives are present during reinforcement learning. We discuss evidence in support of such a general role of the dorsoanterior striatum in implicit motivation.

  8. Recent decrease in typhoon destructive potential and global warming implications (United States)

    Lin, I-I; Chan, Johnny C.L.


    Typhoons (tropical cyclones) severely impact the half-billion population of the Asian Pacific. Intriguingly, during the recent decade, typhoon destructive potential (Power Dissipation Index, PDI) has decreased considerably (by ∼35%). This decrease, paradoxically, has occurred despite the increase in typhoon intensity and ocean warming. Using the method proposed by Emanuel (in 2007), we show that the stronger negative contributions from typhoon frequency and duration, decrease to cancel the positive contribution from the increasing intensity, controlling the PDI. Examining the typhoons' environmental conditions, we find that although the ocean condition became more favourable (warming) in the recent decade, the atmospheric condition ‘worsened' at the same time. The ‘worsened' atmospheric condition appears to effectively overpower the ‘better' ocean conditions to suppress PDI. This stronger negative contribution from reduced typhoon frequency over the increased intensity is also present under the global warming scenario, based on analysis of the simulated typhoon data from high-resolution modelling. PMID:25990561

  9. Legalization of abortion doubtful in Italy. (United States)


    A proposal to legalize abortion has been presented to the Italian parliament by Representative Loris Fortuna. Thus far, the bill has the whole-hearted support of only the Radical Party. The Vatican has already voiced its strong opposition to this legislation. "The proposal to legalize abortion, even in certain circumstances, must inevitably be met with resistance and refusal," said Father Concetti, the Vatican representative. Professor Emanuele Lauricella, secretary of the Italian Obstetrics and Gynecology Society, on the other hand, claimed that abortion should be permitted, not only when an immediate danger to the mother's life exists, but also when there are other, simpler health risks. The passage of the bill in the near future, however, is very doubtful.

  10. Green buildings pay

    DEFF Research Database (Denmark)

    Naboni, Emanuele; Edwards, Brian

    The new edition of ‘Green Buildings Pay’ authored by Brian Edwards and Emanuele Naboni explores the business and professional benefits which derive from architectural design driven by sustainability. With a new sub-title ‘Green Buildings Pay: design, productivity and ecology’ the book argues...... that environmental design has altered how we design, construct and manage buildings. The book has relevance to those who not only design and engineer buildings but to those who commission architecture and those who occupy the products of this process. Hence, the user is a key consideration. The book examines via...... a number of LEED and BREEAM cases the buildings which flow from corporate environmental responsibility. A number of office and university buildings are examined from three main perspectives- the architect, client and user. One key finding is that architectural innovation has been driven by ecological...

  11. Hauntology of Responsibility: Tom Stoppard’s Darkside

    Directory of Open Access Journals (Sweden)

    Tymon Adamczewski


    Full Text Available The article centres on the notion of responsibility in Tom Stoppard’s Darkside (2013. While Pink Floyd’s original album, which inspired the playwright, thematises its connection to ethics in a spectral and hauntological manner, through the use of field recording sound snippets interwoven in the music, the radio play explores the notion of responsibility through what is called “thought experiments.” The article identifies the subversive function of these narrative examples and, following Emanuel Levinas’ suggestions concerning the instability of the link between the philosophical discourse and that of examples, shows the latter’s insolent and disruptive nature. The notion of responsibility is further linked to its discussion by Jacques Derrida in his Gift of Death (1995 which consequently makes it possible to view the relation between responsibility and responding from a subversive, hauntological and undecidable perspective.

  12. Historia del Lupus

    Directory of Open Access Journals (Sweden)

    Alvaro Rodríguez Gama


    Se encontrarán los lectores con una gran cantidad y calidad de biografías sobre investigaciones, médicos y científicos que han enfrentado el reto de tratar de entender y tratar el lupus, desde los médicos clásicos como Hipócrates, Galeno y Celso, los protodermatólogos Daniel Turner, Jean Astruc, Antoine Lorry y Josef von Plenk; el primer dematológo Robert Willam y médicos de los siglos XVIII y XIX como Thomas Bateman, Jean Lous Alibert, Theódore Biett, Olive Rayer, Pierre Cazenave, Antoine Bazin, Ferdinand von Hebra, Moriz Kaposi, Ernest Besnier, Alfred Fournier, Louis Brocq, Jean Darier, el clasificador Jonathan Hutchinson, Paul Unna, William Osler, Emanuel Libman, George Baehr y así decenas de colosos de la ciencia médica, cuyas historias son descritas minuciosamente por el Dr. Iglesias...

  13. “Huellas de africanía”: recreando áfrica en el arte visual contemporáneo

    Directory of Open Access Journals (Sweden)

    Maria Candida Ferreira de Almeida


    Full Text Available El artículo presenta el concepto huellas de africanía, creado en el campo de la antropología, para explicar la permanencia de imaginarios africanos en la diáspora americana. Los objetivos son: describir cómo este concepto configura una poiética en las artes visuales y evaluar su viabilidad en la constitución de una estética negra. Se analizan dos artistas visuales contemporáneos: Emanuel Araújo (Brasil y Mercedes Angola (Colombia, quienes buscan vincular su obra con África, en procesos que pueden caracterizarse como profundamente eruditos, pues ambos conocen aspectos históricos y filosóficos del África representada, imaginada, creada y recreada en la diáspora.


    Directory of Open Access Journals (Sweden)

    Maria Candida Ferreira de Almeida


    Full Text Available El artículo presenta el concepto huellas de africanía, creado en el campo de la antropología, para explicar la permanencia de imaginarios africanos en la diáspora americana. Los objetivos son: describir cómo este concepto configura una poiética en las artes visuales y evaluar su viabilidad en la constitución de una estética negra. Se analizan dos artistas visuales contemporáneos: Emanuel Araújo (Brasil y Mercedes Angola (Colombia, quienes buscan vincular su obra con África, en procesos que pueden caracterizarse como profundamente eruditos, pues ambos conocen aspectos históricos y filosóficos del África representada, imaginada, creada y recreada en la diáspora.

  15. Heaven on Earth: Swedenborgian Correspondences in the Plan of Chicago

    Directory of Open Access Journals (Sweden)

    Kristen Schaffer


    Full Text Available Daniel Hudson Burnham, the Chicago architect and city planner, is recognized for his work on the development of American tall office building; for the construction of World’s Columbian Exposition of 1893; and for his city plans for Washington, D.C., Cleveland, San Francisco, and Chicago. He is also remembered for the quote “Make no little plans.” What is not recalled is his Swedenborgian faith nor how it influenced his work. Emanuel Swedenborg was a Swedish scientist and engineer who, beginning in the mid 1730s, underwent a spiritual awakening. The focus of his work changed to the mystical aspects of human experience. He believed that all Christian churches were dead and in need of revitalization and the key to revitalization was to be found in a new interpretation of scripture. His followers founded the Church of the New Jerusalem, sometimes referred to as the New Church or the Swedenborgian Church.

  16. The façades along the Cassaro in Palermo: historical-building characterization, degradation, restoration norms for interventions

    Directory of Open Access Journals (Sweden)

    Giovanni Fatta


    Full Text Available The good-will to operate in the old town privileging the history and the maintenance of historic buildings, is manifest in this study on the Vittorio Emanuele monumental street, the foundation axis of Palermo, and it’s architectural degraded and disfigured fronts. The search concerning sixty civil buildings is based initially on a cognitive process that includes historical analysis, geometric and dimensional survey, investigation on constituent materials and decay systems, in relation to environmental or anthropic causes. The study includes a design proposal that, according to the individuality of cases, it would represent an intervention code about some recurrent critical aspects on which it’s possible to intervene only applying codified procedures. The proposed designs show so an application to concrete cases, not abdicating to involve physical and economic urban environment: the re-qualification of building materials and architectural language would respect the historical image without depressing the market demands.

  17. "Kids not rights, is their craving": sex education, gay rights, and the threat of gay teachers. (United States)

    Graydon, Michael


    In July 1977, the Ontario Humans Rights Commission recommended adding sexual orientation to the Code. This move was generally supported but Toronto newspapers and evangelists sought assurances that school boards could still dismiss homosexual teachers. They demanded children be shielded from gay teachers, who they accused of sexual predation. I historically link this to a reenergized fear of homosexuals which emerged during Toronto sex education debates in the 1970s. Later, influenced by Anita Bryant's Save the Children crusade, Toronto newspapers and evangelists argued gay teachers were the dangerous effect of gay rights. After the 1977 murder of Emanuel Jaques and the publication of Gerald Hannon's "Men Loving Boys, Loving Men" article, anti-gay sentiment in Toronto exploded, temporarily halting the progress of gay rights.

  18. From the ideal market to the ideal clinic: constructing a normative standard of fairness for human subjects research. (United States)

    Phillips, Trisha


    Preventing exploitation in human subjects research requires a benchmark of fairness against which to judge the distribution of the benefits and burdens of a trial. This paper proposes the ideal market and its fair market price as a criterion of fairness. The ideal market approach is not new to discussions about exploitation, so this paper reviews Wertheimer's inchoate presentation of the ideal market as a principle of fairness, attempt of Emanuel and colleagues to apply the ideal market to human subjects research, and Ballantyne's criticisms of both the ideal market and the resulting benchmark of fairness. It argues that the criticism of this particular benchmark is on point, but the rejection of the ideal market is mistaken. After presenting a complete account of the ideal market, this paper proposes a new method for applying the ideal market to human subjects research and illustrates the proposal by considering a sample case.

  19. Radiation protection in brachytherapic treatment of prostatic carcinoma

    Energy Technology Data Exchange (ETDEWEB)

    Mannino, G.; Bona, R.; Occhipinti, A. [Catania Univ. Hospital, ' Vittorio Emanuele, Ferrarotto e Santo Bambino' (Italy); Testagrossa, B.; Vermiglio, G.; Tripepi, M.G. [Messina Univ., Dept. of Protezionistica Ambientale, Sanitaria, Sociale ed Industriale (Italy)


    Purpose: To evaluate absorbed doses for medical staff and general public deriving from prostate brachytherapy with I-125 seeds. Methods And Materials: Radiation exposure measurements were made for staff and on a subset of 64 patients of the 100 trans perineal I-125 implanted seeds implants at the Vittorio Emanuele, Ferrarotto e Santo Bambino Universitary Hospital. Results: Absorbed doses for operators are very low when using radiation safety devices. The exposure rate at the anterior skin surface due to I-125 implanted seeds ranged from 32 to 120 {mu}Sv/hour. Conclusions: The evaluation of dose measurements shows that radiation risk associated to this practice is very low, both for staff that for critical group of population, if they follow the specific radioprotection statements supplied by health physicists. (authors)

  20. Radiation protection in brachytherapic treatment of prostatic carcinoma

    International Nuclear Information System (INIS)

    Mannino, G.; Bona, R.; Occhipinti, A.; Testagrossa, B.; Vermiglio, G.; Tripepi, M.G.


    Purpose: To evaluate absorbed doses for medical staff and general public deriving from prostate brachytherapy with I-125 seeds. Methods And Materials: Radiation exposure measurements were made for staff and on a subset of 64 patients of the 100 trans perineal I-125 implanted seeds implants at the Vittorio Emanuele, Ferrarotto e Santo Bambino Universitary Hospital. Results: Absorbed doses for operators are very low when using radiation safety devices. The exposure rate at the anterior skin surface due to I-125 implanted seeds ranged from 32 to 120 μSv/hour. Conclusions: The evaluation of dose measurements shows that radiation risk associated to this practice is very low, both for staff that for critical group of population, if they follow the specific radioprotection statements supplied by health physicists. (authors)

  1. The Politics of Genre and Medium apropos of Frank O’Hara’s “On Seeing Larry Rivers’s Washington Crossing the Delaware (1955)

    DEFF Research Database (Denmark)

    Balle, Søren Hattesen

    Frank O’Hara’s ekphrastic poem “On Seeing Larry Rivers’s Washington Crossing the Delaware” is only one work among others in a series of 1950s works in different genres and media relating to Emanuel Leutze’s romantic representation of the father of the American nation in his painting Washington...... event in American history. Inversely, only few critics take seriously the difference in both genre and medium between these different textual and graphic representations of Washington’s crossing and the questions such a difference may give rise to. In this paper I shall make an intergeneric......) and by narrativizing Rivers’s painting, the poem opens up alternative representational possibilities of the former and thus poses the question of whose ‘truth’ gets told or not told depending on the choice of genre and medium in representation. Thus, the intertextual relationship existing between Rivers’s painting...

  2. Towards a Statistical Model of Tropical Cyclone Genesis (United States)

    Fernandez, A.; Kashinath, K.; McAuliffe, J.; Prabhat, M.; Stark, P. B.; Wehner, M. F.


    Tropical Cyclones (TCs) are important extreme weather phenomena that have a strong impact on humans. TC forecasts are largely based on global numerical models that produce TC-like features. Aspects of Tropical Cyclones such as their formation/genesis, evolution, intensification and dissipation over land are important and challenging problems in climate science. This study investigates the environmental conditions associated with Tropical Cyclone Genesis (TCG) by testing how accurately a statistical model can predict TCG in the CAM5.1 climate model. TCG events are defined using TECA software @inproceedings{Prabhat2015teca, title={TECA: Petascale Pattern Recognition for Climate Science}, author={Prabhat and Byna, Surendra and Vishwanath, Venkatram and Dart, Eli and Wehner, Michael and Collins, William D}, booktitle={Computer Analysis of Images and Patterns}, pages={426-436}, year={2015}, organization={Springer}} to extract TC trajectories from CAM5.1. L1-regularized logistic regression (L1LR) is applied to the CAM5.1 output. The predictions have nearly perfect accuracy for data not associated with TC tracks and high accuracy differentiating between high vorticity and low vorticity systems. The model's active variables largely correspond to current hypotheses about important factors for TCG, such as wind field patterns and local pressure minima, and suggests new routes for investigation. Furthermore, our model's predictions of TC activity are competitive with the output of an instantaneous version of Emanuel and Nolan's Genesis Potential Index (GPI) @inproceedings{eman04, title = "Tropical cyclone activity and the global climate system", author = "Kerry Emanuel and Nolan, {David S.}", year = "2004", pages = "240-241", booktitle = "26th Conference on Hurricanes and Tropical Meteorology"}.

  3. Noninvasive monitoring of the genetic evolution of EGFR-mutant non-small-cell lung cancer by analyzing circulating tumor DNA during combination chemotherapy with gefitinib and pemetrexed or S-1

    Directory of Open Access Journals (Sweden)

    Nakahara Y


    Full Text Available Yoshiro Nakahara,1,2 Yusuke Takagi,1,3 Yukio Hosomi,1 Akiko Kagei,4 Tomohiro Yamamoto,4 Takeshi Sawada,5 Makiko Yomota,1 Yusuke Okuma,1 Shinichiro Mikura,1,6 Tatsuru Okamura1 1Department of Thoracic Oncology and Respiratory Medicine, Tokyo Metropolitan Cancer and Infectious Diseases Center Komagome Hospital, Tokyo, 2Department of Respiratory Medicine, Kitasato University School of Medicine, Sagamihara, 3Oncology Scientific Affairs, Merck Sharp & Dohme Corp, 4GeneticLab Co., Ltd., Sapporo, 5Department of Medical Oncology, Tokyo Metropolitan Cancer and Infectious Diseases Center Komagome Hospital, Tokyo, 6Department of Respiratory Medicine, Fujieda Municipal General Hospital, Fujieda, Japan Background: Repetitive genotyping is useful to assess the genetic evolution of non-small-cell lung cancer (NSCLC during treatment, but the need for sampling by biopsy is a major obstacle. Digital polymerase chain reaction (PCR is a promising procedure for the detection of mutant alleles in plasma of cancer patients.Methods: This prospective study enrolled patients with NSCLC and known epidermal growth factor receptor (EGFR mutations and who had experienced disease progression during ongoing EGFR-tyrosine kinase inhibitor (TKI therapy. Eligible patients received daily gefitinib and either pemetrexed or S-1 every 3 weeks until disease progression or the development of unacceptable toxicity. Peripheral blood was collected before and after the combination therapy for digital PCR and hepatocyte growth factor measurement.Results: From May 2012 to January 2014, nine patients with a median age of 67 (range 52–80 years were enrolled. Patterns of disease progression during adjacent EGFR-TKI therapy were acquired resistance, observed in seven patients, and primary resistance, observed in two patients. Known EGFR mutations were detected in plasma samples of six (67% patients at study enrollment. Of these, T790M mutation was concurrently detected in three (50% patients

  4. Black Swan Tropical Cyclones (United States)

    Emanuel, K.; Lin, N.


    Virtually all assessments of tropical cyclone risk are based on historical records, which are limited to a few hundred years at most. Yet stronger TCs may occur in the future and at places that have not been affected historically. Such events lie outside the realm of historically based expectations and may have extreme impacts. Their occurrences are also often made explainable after the fact (e.g., Hurricane Katrina). We nickname such potential future TCs, characterized by rarity, extreme impact, and retrospective predictability, "black swans" (Nassim Nicholas Taleb, 2007). As, by definition, black swan TCs have yet to happen, statistical methods that solely rely on historical track data cannot predict their occurrence. Global climate models lack the capability to predict intense storms, even with a resolution as high as 14 km (Emanuel et al. 2010). Also, most dynamic downscaling methods (e.g., Bender et al. 2010) are still limited in horizontal resolution and are too expensive to implement to generate enough events to include rare ones. In this study, we apply a simpler statistical/deterministic hurricane model (Emanuel et al. 2006) to simulate large numbers of synthetic storms under a given (observed or projected) climate condition. The method has been shown to generate realistic extremes in various basins (Emanuel et al. 2008 and 2010). We also apply a hydrodynamic model (ADCIRC; Luettich et al. 1992) to simulate the storm surges generated by these storms. We then search for black swan TCs, in terms of the joint wind and surge damage potential, in the generated large databases. Heavy rainfall is another important TC hazard and will be considered in a future study. We focus on three areas: Tampa Bay in the U.S., the Persian Gulf, and Darwin in Australia. Tampa Bay is highly vulnerable to storm surge as it is surrounded by shallow water and low-lying lands, much of which may be inundated by a storm tide of 6 m. High surges are generated by storms with a broad

  5. L’imminenza del "doppio”. Opere e allestimenti di Edoardo Persico / The imminence of the “double”. Edoardo Persico’s works and displays

    Directory of Open Access Journals (Sweden)

    Roberto Cresti


    Full Text Available Edoardo Persico, animatore instancabile di dibattiti e ricerche in ambito artistico, ha progettato, a Milano, nella prima metà degli anni Trenta, una serie di strutture espositive – dalla Costruzione metallica pubblicitaria (1934, posta sotto la Galleria Vittorio Emanuele, alla Sala delle Medaglie d’oro per la Mostra dell’Aeronautica (1934, entrambe in collaborazione con Marcello Nizzoli – destinate al grande pubblico. In esse si riconosce una essenzialità razionale, che non costituisce la messa in pratica di un esprit de géométrie aridamente calcolante, bensì lo sviluppo di un esprit de fi nesse che risulta in implicito contrasto con gli intenti propagandistici assegnati in quegli anni dal regime fascista alla architettura italiana. L’ultimo lavoro di Persico fu il Salone d’onore alla VI Triennale (1936 – progettato ancora con Nizzoli, Giancarlo Palanti e Lucio Fontana –, che tuttavia egli non fece in tempo a vedere realizzato, nel cui luminoso silenzio culmina una visione delle forme che, comunque in sintonia con la vita e con un sentimento di socialità regolata da ideali egualitari, rivela anche un fondamento spirituale, un “doppio” che Persico non smise mai di ricercare. Edoardo Persico, tireless animator of debates and research in arts, has designed, in Milan, during the fi rst half of the thirties, a series of exhibition facilities – from advertising Metal construction (1934, placed under the Vittorio Emanuele Gallery, to the Hall of the Gold Medals for Aeronautics Exhibition (1934, both in collaboration with Marcello Nizzoli – for the general public. In these he shows a rational simplicity, which doesn’t constitute the implementation of an esprit de géométrie dryly calculating, but the development of an esprit de fi nesse which results in an implicit contrast with the propaganda awarded in those years by the fascist regime to Italian architecture. His last work was the Hall of Honor at the VI Triennale

  6. Contributions to the 14. Geoengineering congress in Munich. Geoengineering with the parameters time and quality; Beitraege zum 14. Geotechnik-Tag in Muenchen. Geotechnik mit den Parametern Zeit und Qualitaet

    Energy Technology Data Exchange (ETDEWEB)

    Vogt, Norbert (ed.)


    This proceedings contains the following twelve papers: Why time and quality play a role? (Gebhard Dausch); Models for settlement prediction of structures in opencast dumps (Emanuel Birle, Stefan Vogt); Quality improvement and risk reduction through alternative proposals? Example: Intake structure of a coal-fired plant Wilhelmshaven (Thomas Brand, Friderike Hamm); History and methodology of the development of the combined pile and raft foundation (Rolf Katzenbach); Hazardous waste dump at Malsch - long-term monitoring of the safety measures (Walter Laechler, Fred Dietzel); Murphy's Law on the example of Protzenweiher Bridge (Markus Herten, Andreas Beier); ''Permanent anchor'' - state of the art and long-term experience with the durability of ground anchors (Karsten Beck House, Henning Lesemann); Optimized quality management of the implementation of DSM-works (W. Sondermann, W. Wehr); Subway construction in Doha on the example of the Green Line (Guenther Heilmayer); Marmaray Project - Bosphorus Crossing tunnels and stations - Geotechnical Aspects (Nurettin Demir); Crossrail C310 Thames Tunnel, geotechnical and tunnel construction challenges in urban tunnelling with variable ground conditions (Andreas Raedle, Stephan Assenmacher, Esters Sophia Karl); Proof concept of establishing the underground central station Stuttgart 21 - Numerical modeling and calibration (Roberto Cudmani). [German] Dieser Tagungsband enthaelt folgende zwoelf Beitraege: Warum Zeit und Qualitaet eine Rolle spielen (Gebhard Dausch); Modelle zur Setzungsprognose von Bauwerken auf Tagebaukippen (Emanuel Birle, Stefan Vogt); Qualitaetsverbesserung und Risikominimierung durch Sondervorschlaege? Beispiel: Entnahmebauwerk Kohlekraftwerk Wilhelmshaven (Thomas Brand, Friderike Hamm); Historie und Methodik der Entwicklung der Kombinierten Pfahl-Plattengruendung (KPP) (Rolf Katzenbach); Langzeitkontrolle der Sicherungsmassnahmen der Sonderabfalldeponie Malsch (Walter Laechler, Fred

  7. Gesti convenzionali e arte mimica nell’Ottocento italiano

    Directory of Open Access Journals (Sweden)

    Noemi Massari


    Full Text Available The present essay aims at reviewing the issues and methodologies faced in my PhD research. The first step will be the analysis of the theoretical assumptions that underlie the emergence of ballet pantomime and the rediscovery of classical pantomime. The essay will proceed outlining the artistic and cultural landscapes of the two Italian cities examined, Milan and Naples, aiming at defining, from a didactic viewpoint, the teaching of pantomime in the two largest Italian academies, the Teatro alla Scala in Milan and the Teatro di San Carlo in Naples. The third step will be the recording of the few references to the mime art contained in the treaties and documents relating to the dance in Italy during the Nineteenth century (Carlo Blasis, Vincenzo Buonsignori, Giulio Pompeo Ferrario. These references will be compared to the major mime treatises for actors (Giovanni Emanuele Bideri, Antonio Morrocchesi, Angelo Canova, Alemanno Morelli and opera singers (Manuel Garcia, Fernando Pelzet, Leone Giraldoni, Enrico Serafino Torelli, Augusto Delle Sedie in order to analyze the development of gesture during the Nineteenth century and the different use that each interpreter did of the expressive mime.

  8. Poseta Milana Stojadinovića Italiji decembra 1937.

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    Bojan Simić


    Full Text Available The official visit of Yugoslav Prime Minister and Minister of Foreign Affairs, Milan Stojadinović to Italy at the beginning of December 1937 is considered to be a courtesy call following Italian Foreign Minister Ciano’s visit to Belgrade in March 1937 when Italian-Yugoslav Agreement was signed. During his stay in Rome, Stojadinović met Mussolini and talked about the current situation in Europe and foreign policies of two countries. He was also received by Italian King Victor Emanuel III and pope Pius XI. The second part of the visit took place in Milano were Yugoslav Prime Minister visited industrial complex and military center. Although no new agreements were signed, this visit is vitally important for understanding the politics of the two governments in the following months and years. The press of both countries paid much attention to this visit and informed their public regularly and in detail about it. Leading Italian newspapers Corriere della Sera and La Stampa and Yugoslav Politika and Vreme were in the forefront. Hundreds of articles were written, dozen new photos were made and published on front pages. Italian and Yugoslav newspapers often republished foreign articles about the visit but exclusively theose with positive connotation, considering the visit as a crucial act for European peace at the time.

  9. Note & Recensioni

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    Full Text Available VolumiVito Campanelli, Web Aesthetics. How Digital Media Affect Culture and Society; Id., Remix It Yourself. Analisi socio-estetica delle forme comunicative del Web [Emanuele Crescimanno] • Jean-François Bordron, Image et vérité. Essais sur les dimensions iconiques de la connaissance [Veronica Estay Stange] • Stéphane Dumas, Les peaux créatrices – Esthétique de la sécrétion [Marc-Vincent Howlett]NoteQuidam veritatis effectus. A proposito di A Plea for Balance in Philosophy. Essays in honour of Paolo Parrini [Fabrizio Desideri] • A Single Face to Capture the Whole World: Literary Shapes and Shadows. An Interview With Tolm Coibin [Fabrizia Abbate] •Convegno Le sensible a l’oeuvre: savoirs du corps entre esthetique et neurosciences, Parigi, 15 Maggio 2014 [Jessica Murano] 


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    Rafael Miranda Redondo


    Full Text Available En el artículo a continuación abordamos la recepción de la obra de Castoriadis enAmerica Latina a través de un ejercicio de dialogo con uno de los autores del numero 11de PROMETEICA, Emanuele Profumi. En particular nos ocupamos de ilustrar elcontexto en el que dicha obra es recibida por los medios académicos y políticos en elcontinente gracias a los desarrollos de Castoriadis en torno al fenómeno descrito deaumento de la insignificancia, poniendo un énfasis particular en la noción dedescomposición social en cuya base se encontraría la crisis de autoreferencia en lasociedad contemporánea. Para argumentar la relevancia de la noción dedescomposición social hacemos uso de la manera como Castoriadis aborda la cuestióndel proyecto social en occidente y de la manera como su ausencia tiene un efectodefinitivo para la relación de occidente a nivel global y muy particularmente respecto alabismo que lo separa del mundo Árabe. Damos cuenta de todo ello teniendo delante losrecientes atentados en Paris y el conflicto actual que involucra las potencias mundialesy el Estado Islámico.

  11. Is it justifiable to assert that clinical lycanthropy may be correlated to porphyria cutanea tarda?

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    Lorenzo Martini


    Full Text Available Scope of this study is to demonstrate an old theory expressed in 1963, when Illis (Guy’s Hospital in London established a correlation between the clinical lycanthropy and congenital porphyria cutanea tarda. We had the fortune to live in a village where they say a lycanthrope lives too and is accustomed to hid himself at home for the 3 days when on the full moon, when he becomes (and behaves as a werewolf. Werewolves like to walk around before dawn craving for water and since We love to walk very early in the morning (as philosopher Emanuel Kant used to do, We have had this chance to encounter this mysterious man, who is a normal man with a regular lifestyle according to lunar cycle. He presents a very pale face with scares and blisters and generally when somebody asks him about this cutaneous manifestations he says he detests sun and light and his skin reacts by this way. We attempted to treat this individual by a pomade containing rutin, diosmin,Centella asiatica,niacinamide and escin. Results are encouraging as well.

  12. Contributions to the 14. Geoengineering congress in Munich. Geoengineering with the parameters time and quality

    International Nuclear Information System (INIS)

    Vogt, Norbert


    This proceedings contains the following twelve papers: Why time and quality play a role? (Gebhard Dausch); Models for settlement prediction of structures in opencast dumps (Emanuel Birle, Stefan Vogt); Quality improvement and risk reduction through alternative proposals? Example: Intake structure of a coal-fired plant Wilhelmshaven (Thomas Brand, Friderike Hamm); History and methodology of the development of the combined pile and raft foundation (Rolf Katzenbach); Hazardous waste dump at Malsch - long-term monitoring of the safety measures (Walter Laechler, Fred Dietzel); Murphy's Law on the example of Protzenweiher Bridge (Markus Herten, Andreas Beier); ''Permanent anchor'' - state of the art and long-term experience with the durability of ground anchors (Karsten Beck House, Henning Lesemann); Optimized quality management of the implementation of DSM-works (W. Sondermann, W. Wehr); Subway construction in Doha on the example of the Green Line (Guenther Heilmayer); Marmaray Project - Bosphorus Crossing tunnels and stations - Geotechnical Aspects (Nurettin Demir); Crossrail C310 Thames Tunnel, geotechnical and tunnel construction challenges in urban tunnelling with variable ground conditions (Andreas Raedle, Stephan Assenmacher, Esters Sophia Karl); Proof concept of establishing the underground central station Stuttgart 21 - Numerical modeling and calibration (Roberto Cudmani). [de

  13. Competition or cooperation?

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    Robbins RA


    Full Text Available No abstract available. Article truncated at 150 words. One of our local institutions, the Mayo Clinic Arizona, was mentioned in a recent op-ed in the New York Times. The editorial entitled, “It Costs More, but Is It Worth More?” by Ezekiel J. Emanuel and Steven D. Pearson (1, criticizes the Mayo Clinic in Rochester and Arizona for building two new proton beam treatment facilities at a cost of more than $180 million dollars each. It accuses the Mayo Clinic of participating in “…a medical arms race for proton beam machines, which could cost taxpayers billions of dollars for a treatment that, in many cases, appears to be no better than cheaper alternatives”. The editorial states that except for a handful of rare pediatric cancers, the evidence is lacking for treatment of other types of cancer such as lung, esophageal, breast, head and neck, and prostate cancers.John Noseworthy MD, President and Chief Executive of the Mayo Clinic, replied …

  14. "Med Flid opdigtet"? Om bruken av fabler i Avis for Børn (Kbh. 1779‒1782

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    Bache-Wiig, Harald


    Full Text Available This essay is an investigation into the use of the fable genre in a Danish children’s magazine, Avis for Børn (Journal for the children, published in Copenhagen 1779‒1782 by the philanthropist and editor Emanuel Balling. The main purpose is to indicate that the classical, Aesopian genre to some extent was transformed and adapted to fit into the didactic and religious purpose dominating this journal. Some examples from the old lore are given to substantiate the assumption that the attitude of the fable mainly was a very pragmatic one, without the moral and religious orientation typical of the stories presented in Avis for Børn. In nature, Avis for Børn would admire the reign of a benevolent God, while in ancient fable nature is a place reigned by brutes and by arbitrary bestiality. Nevertheless, the journal chose to make some meaningful, yet strained use of the genre, without twisting the genre into pastoral sentimentality, a tendency that during the 19th century in children’s literature became predominant.

  15. Abitare il transito. Il pensiero delle pratiche di Carlo Sini

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    Paolo Berretta


    Full Text Available In the original Italian philosophical adventure of the last fifty years, the figure of Carlo Sini is certainly one of the most profound and fascinating. His education, begun following the Milanese teaching of Giovanni Emanuele Barié and then of Enzo Paci, therefore between Kant, Hegel and Husserl, opens furthermore to various influences, from American Pragmatism to Nietzsche’s Genealogy, up to contemporary Hermeneutics. Starting from that, Sini has developed the perspective of the thought of the practices that, in the light of the difference between event and meaning, contemplated in an ethical sense, leads to a result that doesn’t exclude the truth, in a relativistic direction. This instead opens up to difference and to the relationship of the future of the «errant planet» (the earth, accepting its Copernican fate. This perspective, provided by great theoretical sharpness, identifies Sini as one of the most interesting contemporary philosophers, and not only at a national level.

  16. Wissen - nihilismus – bejahung: Fichtes transzendentalphilosophischer offenbarungsbegriff

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    Drilo Kazimir


    Full Text Available In dem Zeitraum zwischen 1792 und 1805 entwickelt Johann Gottlieb Fichte zwei verschiedene Bestimmungen des Offenbarungsbegriffs: 1. Offenbarung ist eine auf der göttlichen Autorität beruhende Lehre, mit der das sittliche Handeln gefördert werden soll, 2. Offenbarung ist das Zusammenhalten des Wissens im Sein und so die Rettung vor dem Nihilismus. In dem Beitrag wird gezeigt, dass Fichte in seiner späten Wissenschaftslehre und in ständiger Auseinandersetzung mit Jacobis Kritik, Idealismus sei Nihilismus, mit dieser letzten Bestimmung eine tragfähige Alternative zu dem ersten, traditionellen Offenbarungsbegriff gibt. Offenbarung, so wie Fichte sie in seiner Spätphilosophie versteht, dient weder der Förderung der Moral, noch hält sie den Prozess der Selbsterkenntnis des Absoluten im Gang oder ist eine Entäußerung Gottes. Der Begriff der transzendentalphilosophischen Offenbarung hat vielmehr seine Bedeutung als der Garant der Realität des Wissens. Als Beleg für diese These dienen die Schriften „Versuch einer Kritik aller Offenbarung“, „Erlanger Wissenschaftslehre“ und „Erlanger Logik“. Darüber hinaus wird auf die Interpretation der Fichte‘schen Religionsphilosophie von Emanuel Hirsch eingegangen, der Fichtes Offenbarungsbegriff im Rahmen der theologischen Fragestellung mit dem Gedanken der „Bejahung“ des Absoluten produktiv weiterführt.

  17. Characteristics of Extreme Extratropical Cyclones in a High-Resolution Global Climate Model (United States)

    Catalano, A. J.; Broccoli, A. J.; Kapnick, S. B.; Janoski, T. P.


    In the northeastern United States, many of the strongest impacts from extratropical cyclones (ETCs) are associated with storms that exhibit slow movement, unusual tracks, or exceptional intensity. Examples of extreme ETCs include the Appalachian storm of November 1950, the Perfect Storm of October 1991, and the Superstorm of March 1993. Owing to the rare nature of these events, it is difficult to quantify the associated risks (e.g. high winds, storm surge) given the limited duration of high-quality observational datasets. Furthermore, storms with even greater impacts than those observed may be possible, particularly in a warming climate. In the context of tropical cyclones, Lin and Emanuel (2016) have used the metaphor "grey swans" to refer to high-impact events that have not been observed but may be physically possible. One method for analyzing "grey swans" is to generate a larger sample of ETCs using a coupled climate model. Therefore, we use long simulations (over 1,000 years with atmospheric constituents fixed at 1990 levels) from a global climate model (GFDL FLOR) with 50km atmospheric resolution. FLOR has been shown to realistically simulate the spatial distribution and climatology of ETCs during the reanalysis era. We will discuss the climatological features of these extreme ETC events.

  18. The Tragedy of Work: Working Class Heroes in the Italian 21st-century Literature

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    Claudio Panella


    Full Text Available The paper aims at exploring how the literary representation of the worker has changed between the end of 20th-century and the beginning of the 21st-century. With the fall of the 20th-century ideologies and raising the fragmentation of labour, texts have emerged in Italian literature which illustrated the tragic social and existential condition of the working class. Among these texts we can find some récits de filiation written by sons and daughters of workers whose health and ideals have been undermined even down to death. These typology of texts let emerged two equally tragic characters: fathers, ill and defeated but still working class heroes and sons, tragically conscious of their roles witnesses-superstites of those ‘denied heroes’. Among the texts being tackled in the paper Il nemico (2009 by Emanuele Tonon, Amianto (2012 by Alberto Prunetti, Il fuoco a mare (2015 by Andrea Bottalico, Ilva Football Club (2016 by Fulvio Colucci and Lorenzo d’Alò

  19. Brauer groups and obstruction problems moduli spaces and arithmetic

    CERN Document Server

    Hassett, Brendan; Várilly-Alvarado, Anthony; Viray, Bianca


    The contributions in this book explore various contexts in which the derived category of coherent sheaves on a variety determines some of its arithmetic. This setting provides new geometric tools for interpreting elements of the Brauer group. With a view towards future arithmetic applications, the book extends a number of powerful tools for analyzing rational points on elliptic curves, e.g., isogenies among curves, torsion points, modular curves, and the resulting descent techniques, as well as higher-dimensional varieties like K3 surfaces. Inspired by the rapid recent advances in our understanding of K3 surfaces, the book is intended to foster cross-pollination between the fields of complex algebraic geometry and number theory. Contributors: · Nicolas Addington · Benjamin Antieau · Kenneth Ascher · Asher Auel · Fedor Bogomolov · Jean-Louis Colliot-Thélène · Krishna Dasaratha · Brendan Hassett · Colin Ingalls · Martí Lahoz · Emanuele Macrì · Kelly McKinnie · Andrew Obus · Ekin Ozman · Raman...

  20. D3D augmented reality imaging system: proof of concept in mammography

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    Douglas DB


    Full Text Available David B Douglas,1 Emanuel F Petricoin,2 Lance Liotta,2 Eugene Wilson3 1Department of Radiology, Stanford University, Palo Alto, CA, 2Center for Applied Proteomics and Molecular Medicine, George Mason University, Manassas, VA, 3Department of Radiology, Fort Benning, Columbus, GA, USA Purpose: The purpose of this article is to present images from simulated breast microcalcifications and assess the pattern of the microcalcifications with a technical development called “depth 3-dimensional (D3D augmented reality”. Materials and methods: A computer, head display unit, joystick, D3D augmented reality software, and an in-house script of simulated data of breast microcalcifications in a ductal distribution were used. No patient data was used and no statistical analysis was performed. Results: The D3D augmented reality system demonstrated stereoscopic depth perception by presenting a unique image to each eye, focal point convergence, head position tracking, 3D cursor, and joystick fly-through. Conclusion: The D3D augmented reality imaging system offers image viewing with depth perception and focal point convergence. The D3D augmented reality system should be tested to determine its utility in clinical practice. Keywords: augmented reality, 3D medical imaging, radiology, depth perception

  1. Melting hadrons, boiling quarks from Hagedorn temperature to ultra-relativistic heavy-ion collisions at CERN : with a tribute to Rolf Hagedorn

    CERN Document Server


    This book shows how the study of multi-hadron production phenomena in the years after the founding of CERN culminated in Hagedorn's pioneering idea of limiting temperature, leading on to the discovery of the quark-gluon plasma - announced, in February 2000 at CERN. Following the foreword by Herwig Schopper -- the Director General (1981-1988) of CERN at the key historical juncture -- the first part is a tribute to Rolf Hagedorn (1919-2003) and includes contributions by contemporary friends and colleagues, and those who were most touched by Hagedorn: Tamás Biró, Igor Dremin, Torleif Ericson, Marek Gázdzicki, Mark Gorenstein, Hans Gutbrod, Maurice Jacob, István Montvay, Berndt Müller, Grazyna Odyniec, Emanuele Quercigh, Krzysztof Redlich, Helmut Satz, Luigi Sertorio, Ludwik Turko, and Gabriele Veneziano. The second and third parts retrace 20 years of developments that after discovery of the Hagedorn temperature in 1964 led to its recognition as the melting point of hadrons into boiling quarks, and t...

  2. Recent Decrease in Typhoon Destructive Potential and Global Warming Implications (United States)

    Lin, I. I.


    Despite the severe impact of individual tropical cyclones like Sandy (2012) and Haiyan (2013), global TC activities as a whole have actually dropped considerably since the early 1990's. Especially over the most active and hazardous TC basin on earth, the Western North Pacific (WNP) typhoon Main Development Region (MDR), an evident decrease in TC activity has been observed, as characterised by the drop in the annual Power Dissipation Index (Emanuel 2005). Paradoxically, this decrease occurred despite evident ocean warming, with upper ocean heat content increased by 12% over the western North Pacific MDR (Pun et al. 2013; Lin et al. 2014). This study explores the interesting interplay between atmosphere and ocean on the WNP typhoons. Though ocean may become more favourable (warming) to fuel individual typhoon event through temporal relaxation in the atmosphere condition (e.g. Haiyan in 2013), the overall `worsened' atmospheric condition (e.g. increase in vertical wind shear) can `over-powers' the `better' ocean to suppress the overall WNP typhoon activities. This stronger negative contribution from reduced typhoon frequency over the increased intensity is also present under the global warming scenario, based on analysis of the simulated typhoon data from high-resolution modelling.

  3. Assessing extreme sea levels due to tropical cyclones in the Atlantic basin (United States)

    Muis, Sanne; Lin, Ning; Verlaan, Martin; Winsemius, Hessel; Vatvani, Deepak; Ward, Philip; Aerts, Jeroen


    Tropical cyclones (TCs), including hurricanes and typhoons, are characterised by high wind speeds and low pressure and cause dangerous storm surges in coastal areas. Over the last 50 years, storm surge incidents in the Atlantic accounted for more than 1,000 deaths in the United Stated. Recent flooding disasters, such as Hurricane Katrina in New Orleans in 2005 and, Hurricane Sandy in New York in 2012, exemplify the significant TC surge risk in the United States. In this contribution, we build on Muis et al. (2016), and present a new modelling framework to simulate TC storm surges and estimate their probabilities for the Atlantic basin. In our framework we simulate the surge levels by forcing the Global Tide and Surge Model (GTSM) with wind and pressure fields from TC events. To test the method, we apply it to historical storms that occurred between 1988 and 2015 in the Atlantic Basin. We obtain high-resolution meteorological forcing by applying a parametric hurricane model (Holland 1980; Lin and Chavas 2012) to the TC extended track data set (Demuth et al. 2006; updated), which describes the position, intensity and size of the historical TCs. Preliminary results show that this framework is capable of accurately reproducing the main surge characteristics during past events, including Sandy and Katrina. While the resolution of GTSM is limited for local areas with a complex bathymetry, the overall performance of the model is satisfactory for the basin-scale application. For an accurate assessment of risk to coastal flooding in the Atlantic basin it is essential to provide reliable estimates of surge probabilities. However, the length of observed TC tracks is too short to accurately estimate the probabilities of extreme TC events. So next steps are to statistically extend the observed record to many thousands of years (e.g., Emanuel et al. 2006), in order to force GTSM with a large number of synthetic storms. Based on these synthetic simulations, we would be able to

  4. Cumulus parameterizations in chemical transport models (United States)

    Mahowald, Natalie M.; Rasch, Philip J.; Prinn, Ronald G.


    Global three-dimensional chemical transport models (CTMs) are valuable tools for studying processes controlling the distribution of trace constituents in the atmosphere. A major uncertainty in these models is the subgrid-scale parametrization of transport by cumulus convection. This study seeks to define the range of behavior of moist convective schemes and point toward more reliable formulations for inclusion in chemical transport models. The emphasis is on deriving convective transport from meteorological data sets (such as those from the forecast centers) which do not routinely include convective mass fluxes. Seven moist convective parameterizations are compared in a column model to examine the sensitivity of the vertical profile of trace gases to the parameterization used in a global chemical transport model. The moist convective schemes examined are the Emanuel scheme [Emanuel, 1991], the Feichter-Crutzen scheme [Feichter and Crutzen, 1990], the inverse thermodynamic scheme (described in this paper), two versions of a scheme suggested by Hack [Hack, 1994], and two versions of a scheme suggested by Tiedtke (one following the formulation used in the ECMWF (European Centre for Medium-Range Weather Forecasting) and ECHAM3 (European Centre and Hamburg Max-Planck-Institut) models [Tiedtke, 1989], and one formulated as in the TM2 (Transport Model-2) model (M. Heimann, personal communication, 1992). These convective schemes vary in the closure used to derive the mass fluxes, as well as the cloud model formulation, giving a broad range of results. In addition, two boundary layer schemes are compared: a state-of-the-art nonlocal boundary layer scheme [Holtslag and Boville, 1993] and a simple adiabatic mixing scheme described in this paper. Three tests are used to compare the moist convective schemes against observations. Although the tests conducted here cannot conclusively show that one parameterization is better than the others, the tests are a good measure of the

  5. Sensibilidad al cambio de dominio y resolución de tres configuraciones del modelo climático regional RegCM 4.3 para la región de América Central y el Caribe

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    Alejandro Vichot-Llano


    Full Text Available Se utilizaron tres configuraciones del modelo climático regional RegCM, del ICTP, versión 4.3, para dos dominios en la región de América Central y el Caribe, con tres esquemas de parametrización de cúmulo, con el objetivo de estudiar la sensibilidad del modelo al cambio de resolución y dimensiones del dominio. Los esquemas convectivos utilizados son el de Emanuel (EM, una combinación del esquema de Grell sobre tierra y Emanuel sobre el océano (GE y el esquema de Tiedtke (TI. Las condiciones de frontera se obtuvieron de los reanálisis ERA-Interim. El primer dominio se extendió de 26 a 116 grados oeste y de 5 a 33 grados norte, con 50 km de resolución horizontal, mientras que el segundo, interior a éste, se limitó a una parte de América Central y las Antillas, con resolución de 25 km y se definió un área de estudio común entre ambos dominios para realizar las comparaciones. El periodo de simulación fue desde el año 2000 hasta el 2001. La base de datos satelital TRMM fue usada como criterio de comparación para la precipitación y las del CRU y MERRA para los campos de temperatura. Los resultados alcanzados indican que el modelo posee una habilidad razonable para reproducir los patrones espaciales de la lluvia en el Caribe, pero presenta sesgos cuyo valor depende del esquema de cumulo que utiliza, y en menor medida de la resolución espacial. Para el período poco lluvioso, el modelo presenta poca sensibilidad al cambio de dominio y resolución tanto en la simulación de la precipitación como de la temperatura, donde la combinación GE da los mejores resultados para la precipitación mientras para el periodo lluvioso, TI y GE presentan los menores sesgos independientemente de la resolución, aunque para 25 km, los sesgos son algo menores y presentan una distribución más homogénea en el área de estudio. La temperatura simulada por el modelo fue bien representada por todas las configuraciones, y principalmente por el esquema

  6. Comparison between neurostimulation techniques rapid transcranial magnetic stimulation vs electroconvulsive therapy for the treatment of resistant depression: patient preference and cost-effectiveness

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    Magnezi R


    Full Text Available Racheli Magnezi,1 Emanuel Aminov,1 Dikla Shmuel,2 Merav Dreifuss,1 Pinhas Dannon1,2 1Public Health and Health Systems Management Program, Department of Management, Bar-Ilan University, Ramat Gan, 2Beer Yaakov Mental Health Center affiliated to Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel Objectives: Major depressive disorder (MDD is a common disorder, widely distributed in the population, and is often associated with severe symptoms and functional impairment. It has been estimated that 30% of MDD patients do not benefit adequately from therapeutic interventions, including pharmacotherapy and psychotherapy. Treatment-resistant depression (TRD is generally defined as a failure to achieve remission, despite therapeutic interventions. Aim: The most effective treatment alternatives for TRD are hospitalization, electroconvulsive therapy (ECT, and transcranial magnetic stimulation (TMS. Here we compared the clinical effectiveness of ECT and TMS, including success rates, patient responses, side-effect profiles, and financial worthiness. Results: We found that ECT (P<0.0001 was more effective than TMS (P<0.012 (not statistically significant in group effect in TRD patients. However, ECT patients reported a higher percentage of side effects (P<0.01 and the TMS treatment scored better in terms of patient preference. The cost benefit of ECT was higher than that of TMS (US$2075 vs US$814. Patient’s preferences for treatment could be more intense in the TMS, if the TMS is included in the Health Maintenance Organization’s service list. Conclusion: We propose that both of these treatment options should be available in psychiatric wards, thus expanding the therapeutic toolkit for TRD. Keywords: ECT, TMS, treatment-resistant depression, cost benefit, patient preference

  7. [The re-introduction of malaria in the Pontine Marshes and the Cassino district during the end of World War II. Biological warfare or global war tactics?]. (United States)

    Sabbatani, Sergio; Fiorino, Sirio; Manfredi, Roberto


    After the fall of the Fascist regime on September 8, 1943, Italy was split into two parts: (i) the Southern regions where the King Victor Emanuel III and the military general staff escaped was under the control of English-American allied armies, and (ii) the northern regions comprising Lazio, Tuscany, Umbria, and Marche still under the control of the Germans. The German Wehrmacht, after suffering several defeats on Southern lines, established a new strengthened line of defence called the Gustav line, located south of Rome and crossing in the western portion the recently-drained Pontine Marshes. In his book published in 2006, Frank Snowden hypothesised that occupying German armies in 1943 had initiated a programme of re-flooding the Pontine plain as a biological warfare strategy to re-introduce malaria infection in the territories south of Rome, Such a plan was intended (i) to slow down the advance of English-American forces, and (ii) to punish Italians who abandoned their former allies. Other authors, including Annibale Folchi, Erhard Geissler, and Jeanne Guillemin, have disputed this hypothesis based on an analysis of recently-uncovered archive documents. What is not disputed is that the flooding of the Pontine and Roman plains in 1943 contributed to a severe malaria epidemic in 1944, which was associated with exceptionally high morbidity and mortality rates in the afflicted populations. Herein, we critically evaluate the evidence and arguments of whether the Wehrmacht specifically aimed to spread malaria as a novel biological warfare strategy in Italy during the Second World War. In our opinion, evidence for specific orders to deliberately spread malaria by the German army is lacking, although the strategy itself may have been considered by Nazis during the waning years of the war.

  8. Effects of bilateral vestibular nucleus lesions on cardiovascular regulation in conscious cats. (United States)

    Mori, R L; Cotter, L A; Arendt, H E; Olsheski, C J; Yates, B J


    The vestibular system participates in cardiovascular regulation during postural changes. In prior studies (Holmes MJ, Cotter LA, Arendt HE, Cas SP, and Yates BJ. Brain Res 938: 62-72, 2002, and Jian BJ, Cotter LA, Emanuel BA, Cass SP, and Yates BJ. J Appl Physiol 86: 1552-1560, 1999), transection of the vestibular nerves resulted in instability in blood pressure during nose-up body tilts, particularly when no visual information reflecting body position in space was available. However, recovery of orthostatic tolerance occurred within 1 wk, presumably because the vestibular nuclei integrate a variety of sensory inputs reflecting body location. The present study tested the hypothesis that lesions of the vestibular nuclei result in persistent cardiovascular deficits during orthostatic challenges. Blood pressure and heart rate were monitored in five conscious cats during nose-up tilts of varying amplitude, both before and after chemical lesions of the vestibular nuclei. Before lesions, blood pressure remained relatively stable during tilts. In all animals, the blood pressure responses to nose-up tilts were altered by damage to the medial and inferior vestibular nuclei; these effects were noted both when animals were tested in the presence and absence of visual feedback. In four of the five animals, the lesions also resulted in augmented heart rate increases from baseline values during 60 degrees nose-up tilts. These effects persisted for longer than 1 wk, but they gradually resolved over time, except in the animal with the worst deficits. These observations suggest that recovery of compensatory cardiovascular responses after loss of vestibular inputs is accomplished at least in part through plastic changes in the vestibular nuclei and the enhancement of the ability of vestibular nucleus neurons to discriminate body position in space by employing nonlabyrinthine signals.

  9. The LMDZ4 general circulation model: climate performance and sensitivity to parametrized physics with emphasis on tropical convection

    Energy Technology Data Exchange (ETDEWEB)

    Hourdin, Frederic; Musat, Ionela; Bony, Sandrine; Codron, Francis; Dufresne, Jean-Louis; Fairhead, Laurent; Grandpeix, Jean-Yves; LeVan, Phu; Li, Zhao-Xin; Lott, Francois [CNRS/UPMC, Laboratoire de Meteorologie Dynamique (LMD/IPSL), Paris Cedex 05 (France); Braconnot, Pascale; Friedlingstein, Pierre [Laboratoire des Sciences du Climat et de l' Environnement (LSCE/IPSL), Saclay (France); Filiberti, Marie-Angele [Institut Pierre Simon Laplace (IPSL), Paris (France); Krinner, Gerhard [Laboratoire de Glaciologie et Geophysique de l' Environnement, Grenoble (France)


    The LMDZ4 general circulation model is the atmospheric component of the IPSL-CM4 coupled model which has been used to perform climate change simulations for the 4th IPCC assessment report. The main aspects of the model climatology (forced by observed sea surface temperature) are documented here, as well as the major improvements with respect to the previous versions, which mainly come form the parametrization of tropical convection. A methodology is proposed to help analyse the sensitivity of the tropical Hadley-Walker circulation to the parametrization of cumulus convection and clouds. The tropical circulation is characterized using scalar potentials associated with the horizontal wind and horizontal transport of geopotential (the Laplacian of which is proportional to the total vertical momentum in the atmospheric column). The effect of parametrized physics is analysed in a regime sorted framework using the vertical velocity at 500 hPa as a proxy for large scale vertical motion. Compared to Tiedtke's convection scheme, used in previous versions, the Emanuel's scheme improves the representation of the Hadley-Walker circulation, with a relatively stronger and deeper large scale vertical ascent over tropical continents, and suppresses the marked patterns of concentrated rainfall over oceans. Thanks to the regime sorted analyses, these differences are attributed to intrinsic differences in the vertical distribution of convective heating, and to the lack of self-inhibition by precipitating downdraughts in Tiedtke's parametrization. Both the convection and cloud schemes are shown to control the relative importance of large scale convection over land and ocean, an important point for the behaviour of the coupled model. (orig.)

  10. Do we need more than just powerful blood pressure reductions? New paradigms in end-organ protection

    Directory of Open Access Journals (Sweden)

    Domenico Galzerano


    Full Text Available Domenico Galzerano1, Cristina Capogrosso1, Sara Di Michele2, Emanuele Bobbio3, Paola Paparello1, Carlo Gaudio21Department of Cardiology, San Gennaro Hospital, Naples, Italy; 2Department of Heart and Great Vessels, A. Reale, La Sapienza University, Rome, Italy; 3Department of Cardiovascular Sciences, Federico II University, Naples, ItalyAbstract: Antihypertensive therapy can lower the risk of cardiovascular morbidity and mortality. Yet, partly because of inadequate dosing, wrong pharmacological choices, and poor patient adherence, hypertension control remains suboptimal in the majority of hypertensive patients. Achieving greater blood pressure control requires a multifaceted approach that raises awareness of hypertension, uses effective therapies, and improves adherence. Particular classes of antihypertensive therapy have beneficial actions beyond blood pressure and studies have evaluated differences in cardiovascular protection among classes. The LIFE and HOPE studies showed between-class differences that may be due to effects other than blood pressure-lowering. In the ONTARGET study, telmisartan and ramipril provided similar cardiovascular protection but adherence was higher with telmisartan, which was better tolerated. This difference in compliance is likely to be important for long-term therapy. The selection of an agent for cardiovascular protection should depend on an appreciation of its composite properties, including any beneficial effects on tolerability and increased patient adherence, as these are likely to be advantageous for the long-term management of hypertension. This review examines the evidence that the effects beyond blood pressure provided by some antihypertensive agents can also lower the risk of cardiovascular, cerebrovascular, and renal events in patients with hypertension.Keywords: angiotensin II receptor blocker, cardiovascular continuum, cardiovascular disease, hypertension, renin–angiotensin system, telmisartan

  11. The Recipe for Corporate Longevity: From the Perspective of "Managing Innovation". (United States)

    Griesar, Klaus; Bessant, John; Bernschneider-Reif, Sabine


    The elephant is in the room-a metaphorical idiom for an obvious problem or risk that nobody wants to discuss. This abstract is not intended to be a summary, to reveal major findings, or unveil conclusions. On the contrary, it is aimed to provoke curiosity as to the question of corporate survival. Is there any recipe to be followed for companies to achieve this? The answer comes neither from the modest and traditional study rooms of philosophers nor the recent fact-based studies from the offices (and well-paid opinions) of business consultants. The Archimedean point from which we can objectively explore the subject of corporate survival does not exist. Instead we offer seven analogies (or metaphors) as intellectual platforms where new perspectives can be considered. Innovation obviously plays a major role in corporate survival-yet, by its nature all innovation is messy. In order to reduce entropy, this abstract reveals some keywords in alphabetical order starting from A, such as ambidexterity, architecture, and ant colonies, moving on to B, such as, (mental) boxes and biodiversity. For obvious reasons, C plays a major role-sufficiently that we have already revealed curiosity as one part of the answer-treading over to D (Darwin, DNA, and discontinuity), followed by E (earthquakes and evolution). As a final warning signal in order to manage the expectation: It is not the intention of this article to give a comprehensive overview about the rich and complex history of Merck KGaA, Darmstadt, Germany. Indeed, only the final chapter will provide reference to this company: Before the curtains will finally close, an epilogue will start in which one of the protagonists of the 350-year journey of the company-Emanuel Merck-will appear on the stage and "let history speak for itself". Still curious? © 2018 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.

  12. E-cigarettes in patients with COPD: current perspectives

    Directory of Open Access Journals (Sweden)

    Morjaria JB


    Full Text Available JB Morjaria,1,2 E Mondati,3,4 R Polosa3–5 1Department of Respiratory Medicine, Royal Brompton and Harefield Hospital Foundation Trust, Harefield Hospital, Harefield, 2Department of Respiratory Medicine, Imperial College, London, UK; 3Department of Clinical and Experimental Medicine, 4Department of Internal and Emergency Medicine, 5Centro per la Prevenzione e Cura del Tabagismo (CPCT, “Policlinico-V. Emanuele,” University of Catania, Catania, Italy Abstract: Conventional cigarette smoking is known to result in significant COPD morbidity and mortality. Strategies to reduce and/or stop smoking in this highly vulnerable patient group are key public health priorities to reduce COPD morbidity and mortality. Unfortunately, smoking cessation efforts in patients with COPD are poor and there is a compelling need for more efficient approaches to cessation for patients with COPD. Electronic cigarettes (ECs are devices that use batteries to vaporize nicotine. They may facilitate quit attempts and cessation in many smokers. Although they are not risk free, ECs are much less harmful than tobacco smoking. Hence, the use of ECs in vulnerable groups and in patients with challenges to abstain or multiple relapses to this habit may be promising. To date, little is known about health consequences of EC use among COPD smokers and whether their regular use has any effects on subjective and objective COPD outcomes. In the current review, we discuss the current perspectives and literature on the role of ECs in abstaining from conventional smoking and the effects of ECs on the respiratory tract in patients with COPD. Keywords: smoking cessation, electronic cigarette, COPD, tobacco harm reduction 

  13. Renal cell carcinoma and a constitutional t(11;22)(q23;q11.2): case report and review of the potential link between the constitutional t(11;22) and cancer. (United States)

    Doyen, Jérôme; Carpentier, Xavier; Haudebourg, Juliette; Hoch, Benjamin; Karmous-Benailly, Houda; Ambrosetti, Damien; Fabas, Thibault; Amiel, Jean; Lambert, Jean-Claude; Pedeutour, Florence


    We observed a t(11;22)(q23-24;q11.2-12) and monosomy 3 in renal tumor cells from a 72-year-old man. The hypothesis of a primitive peripheral neuroectodermal tumor (PPNET) located in the kidney was promptly excluded: Histologically, the tumor was a clear cell renal cell carcinoma (RCC) and we did not observe an EWSR1 gene rearrangement. The constitutional origin of this alteration was established. We report on the second case of RCC in a patient with a constitutional t(11;22). The t(11;22)(q23;q11.2) is the main recurrent germline translocation in humans. Unbalanced translocation can be transmitted to the progeny and can cause Emanuel syndrome. Our observation alerts cancer cytogeneticists to the fortuitous discovery of the constitutional t(11;22) in tumor cells. This translocation appears grossly similar to the t(11;22)(q24;q12) of PPNET and should be evoked if present in all cells of a tumor other than PPNET. This is important when providing appropriate genetic counseling. Moreover, the potential oncogenic role of the t(11;22) and its predisposing risk of cancer are under debate. The family history of the patient revealed a disabled brother who died at an early age from colon cancer and a sister with breast cancer. This observation reopens the issue of a link between the constitutional t(11;22) and cancer, and the utility of cancer prevention workups for t(11;22) carriers. Copyright © 2012 Elsevier Inc. All rights reserved.

  14. Understanding the geographic distribution of tropical cyclone formation for applications in climate models (United States)

    Tory, Kevin J.; Ye, H.; Dare, R. A.


    Projections of Tropical cyclone (TC) formation under future climate scenarios are dependent on climate model simulations. However, many models produce unrealistic geographical distributions of TC formation, especially in the north and south Atlantic and eastern south Pacific TC basins. In order to improve confidence in projections it is important to understand the reasons behind these model errors. However, considerable effort is required to analyse the many models used in projection studies. To address this problem, a novel diagnostic is developed that provides compelling insight into why TCs form where they do, using a few summary diagrams. The diagnostic is developed after identifying a relationship between seasonal climatologies of atmospheric variables in 34 years of ECMWF reanalysis data, and TC detection distributions in the same data. Geographic boundaries of TC formation are constructed from four threshold quantities. TCs form where Emanuel's Maximum Potential Intensity, V_{{PI}}, exceeds 40 {ms}^{{ - 1}}, 700 hPa relative humidity, RH_{{700}}, exceeds 40%, and the magnitude of the difference in vector winds between 850 and 200 hPa, V_{{sh}}, is less than 20 {ms}^{{ - 1}}. The equatorial boundary is best defined by a composite quantity containing the ratio of absolute vorticity (η ) to the meridional gradient of absolute vorticity (β ^{*}), rather than η alone. {β ^*} is also identified as a potentially important ingredient for TC genesis indices. A comparison of detected Tropical Depression (TD) and Tropical Storm (TS) climatologies revealed TDs more readily intensify further to TS where {V_{PI}} is elevated and {V_{sh}} is relatively weak. The distributions of each threshold quantity identify the factors that favour and suppress TC formation throughout the tropics in the real world. This information can be used to understand why TC formation is poorly represented in some climate models, and shows potential for understanding anomalous TC formation

  15. Security in the Baltic region as a Projection of Global Confrontation between Russia and the USA

    Directory of Open Access Journals (Sweden)

    Vadim Volovoj


    Full Text Available This article considers the problem of security in the Baltic region, namely, that of Poland and the Baltics. The authors rely on the works of Karl Deutsch, Emanuel Adler, on Michael Barnett’s theory of security communities and Barry Buzan’s re­gional security complex theory, address Steven Mann’s controlled chaos theory and the concept of Intermarium. Their starting assumption is that the situation in the Baltic depends largely on the politics of external powers — Russia and the United States, — being a projection of their global geopolitical confrontation. The US strategy thus becomes a major part of the equation. The authors believe that since the end of the second Iraq war the American elite has been divided along ideological lines into adherents of the chaos theory and traditionalists thinking in terms of sharing control with the other centres of global power. The US strategy in the Baltic region does not seek an open military conflict with Russia. On the contrary, the US strives to preserve the current level of confrontation between Russia and the EU, convincing the latter of the reality of the Russian threat. Countries that traditionally support confrontation with Russia, Poland and the Bal­tics, serve as a conduit for Washington strategy in Europe and a cordon sanitaire. This function is implemented through the Intermarium project meant to separate Russia from the EU. The four countries are rather active in this area, striving to attain the status of the US principal partners in the region and Europe in general. To retaliate, Moscow does everything within its power to ‘separate’ Brussels from Washington, yet the US influence is still very strong in Europe.

  16. Role of etelcalcetide in the management of secondary hyperparathyroidism in hemodialysis patients: a review on current data and place in therapy

    Directory of Open Access Journals (Sweden)

    Friedl C


    Full Text Available Claudia Friedl,1 Emanuel Zitt2 1Department of Internal Medicine, Clinical Division of Nephrology, Medical University of Graz, Graz, 2Department of Internal Medicine III, Nephrology and Dialysis, Feldkirch Academic Teaching Hospital, Feldkirch, Austria Abstract: Secondary hyperparathyroidism (sHPT is a frequently occurring severe complication of advanced kidney disease. Its clinical consequences include extraskeletal vascular and valvular calcifications, changes in bone metabolism resulting in renal osteodystrophy, and an increased risk of cardiovascular morbidity and mortality. Calcimimetics are a cornerstone of parathyroid hormone (PTH-lowering therapy, as confirmed by the recently updated 2017 Kidney Disease: Improving Global Outcomes chronic kidney disease – mineral and bone disorder clinical practice guidelines. Contrary to calcitriol or other vitamin D-receptor activators, calcimimetics reduce PTH without increasing serum-calcium, phosphorus, or FGF23 levels. Etelcalcetide is a new second-generation calcimimetic that has been approved for the treatment of sHPT in adult hemodialysis patients. Whereas the first-generation calcimimetic cinacalcet is taken orally once daily, etelcalcetide is given intravenously thrice weekly at the end of the hemodialysis session. Apart from improving drug adherence, etelcalcetide has proven to be more effective in lowering PTH when compared to cinacalcet, with an acceptable and comparable safety profile. The hope for better gastrointestinal tolerance with intravenous administration did not come true, as etelcalcetide did not significantly mitigate the adverse gastrointestinal effects associated with cinacalcet. Enhanced adherence and strong reductions in PTH, phosphorus, and FGF23 could set the stage for a future large randomized controlled trial to demonstrate that improved biochemical control of mineral metabolism with etelcalcetide in hemodialysis patients translates into cardiovascular and survival

  17. Pneumoscrotum: report of two different cases and review of the literature

    Directory of Open Access Journals (Sweden)

    Cochetti G


    Full Text Available Giovanni Cochetti,1 Francesco Barillaro,1 Emanuele Cottini,1 Francesco D’Amico,1 Alberto Pansadoro,1 Solajd Pohja,1 Andrea Boni,1 Roberto Cirocchi,2 Veronica Grassi,2 Rosa Mancuso,1 Elisa Silvi,1 Katifenia Ioannidou,1 Maria Giulia Egidi,1 Giulia Poli,1 Ettore Mearini1 1Department of Surgical and Biomedical Science, Institute of Urological, Andrological Surgery and Minimally Invasive Techniques, University of Perugia, Terni, Italy; 2Department of Surgical Sciences, University of Perugia, Terni, Italy Abstract: Pneumoscrotum is the term used to describe the presence of air within the scrotum and includes scrotal emphysema as well as pneumatocele. The etiology varies; in some cases, pneumoscrotum may be due to life-threatening disease like pneumothorax or Fournier gangrene. Despite this, pneumoscrotum is a rarely debated issue. We present two different cases of pneumoscrotum and a review of the literature. The first case report is about a 29 year old male patient affected by Duchenne syndrome who showed pneumoscrotum after cardiopulmonary resuscitation that was performed for asphyxic crisis and cardiovascular arrest. We carried out local puncture with an 18-gauge needle, and the pneumoscrotum was successfully solved. The second case report is about a 56 year old male with pneumoscrotum due to Fournier gangrene who underwent radical exeresis of all necrotic tissues and drainage. This is why most of the scrotal skin and all of the penis skin were removed; as a result, the testicles, epididymis, and cavernosa corpora were externalized. On postoperative day one, the patient was feverless and underwent hyperbaric chamber therapy. No postoperative complications occurred. Accurate evaluation of the pneumoscrotum is always needed. Despite the benign course of most of the clinically evident pneumoscrotum cases, this condition should never be underestimated. Keywords: cardiopulmonary resuscitation, Fournier gangrene, pneumoscrotum, spontaneous causes

  18. Clinical features and imaging findings in a case of Capgras syndrome

    Directory of Open Access Journals (Sweden)

    Luca M


    Full Text Available Maria Luca,1 Andrea Bordone,1 Antonina Luca,2 Andrea Patti,1 Giuseppe Sortino,3 Carmela Calandra11Department of Medical and Surgery Specialties, Psychiatry Unit, 2Department GF Ingrassia, Section of Neuroscience, 3Department of Diagnostic Imaging, Radiology Unit, University Hospital Policlinico-Vittorio Emanuele, Catania, Sicily, ItalyAbstract: Capgras syndrome consists of the delusional belief that a person or persons have been replaced by doubles or impostors. It can occur in the context of both psychiatric and organic illness, and seems to be related to lesions of the bifrontal and right limbic and temporal regions. Indeed, magnetic resonance imaging has revealed brain lesions in patients suffering from Capgras syndrome. This case study reports the findings of a thorough diagnostic evaluation in a woman suffering from Capgras syndrome and presenting with the following clinical peculiarities: obsessive modality of presentation of the delusional ideation, intrusiveness of such ideation (that even disturbed her sleep, as well as a sense of alienation and utter disgust towards the double. These characteristics bring to mind the typical aspects of obsessive-compulsive disorder. Neuroanatomic investigation, through magnetic resonance imaging, performed on this patient showed alteration of the bilateral semioval centers, which are brain regions associated with the emotion of disgust and often show alterations in subjects suffering from obsessive-compulsive disorder. Hence, neuroimaging allows researchers to put forward the hypothesis of a common neuroanatomic basis for Capgras syndrome and obsessive-compulsive disorder, at least for cases in which the delusional ideation is associated with deep feelings of disgust and presents with a certain pervasiveness.Keywords: Capgras syndrome, magnetic resonance imaging, electroencephalography, obsessive-compulsive disorder, semioval centers

  19. Premessa

    Directory of Open Access Journals (Sweden)

    Maria Caterina Federici


    Full Text Available Non è certamente casuale che il centenario della pubblicazione del “Trattato di Sociologia” di Vilfredo Pareto sia trascorso senza un'adeguata attenzione da parte della comunità accademica. I suoi scritti, le sue riflessioni, le sue critiche e le sue prese di posizione pur se ben argomentate e documentate con uno spessore culturale di grande rilievo, sono state sempre “scomode”. La sua testimonianza ha persuasivamente dimostrato che il motivo di ciò è nel riferimento simbolico ma non soltanto alla forma stessa del pensare “in contrapposizione a” e in maniera icastica e senza fare sconti: troppo inusuale per l'intellettuale contemporaneo. Tuttavia l'Università degli Studi di Perugia ha promosso un convegno in occasione del centenario della pubblicazione del “Trattato”. Per questo convegno Silvia Fornari, Andrea Lombardinilo, Uliano Conti, Roberta Iannone, Francesco Antonelli, Maria Luisa Maniscalco, Raffaele Federici, Ilaria Riccioni, Angela Maria Zocchi, Andrea Millefiorini, Emanuele Susca, hanno elaborato alcune dotte riflessioni che si propongono all'attenzione di un pubblico più ampio anche di non specialisti con l'intento, dichiarato, di ri-portare il focus su un Autore, su un periodo storico, su teorie, su problemi, su metodologie e su comparazioni che tanto possono contribuire ad arricchire la trama intellettuale contemporanea che si va impoverendo di “tessuto” appiattendosi su una omogeneità acritica. La gestazione di questi contributi è stata lunga ed ha goduto della maieutica di Orazio Maria Valastro, direttore di “M@gm@”. Le riflessioni nascono con intento celebrativo dei cento anni dalla pubblicazione del “Trattato” ma aprono e attualizzano le teorie paretiane alla contemporaneità.

  20. Cost and effectiveness of omega-3 fatty acid supplementation in Chinese ICU patients receiving parenteral nutrition

    Directory of Open Access Journals (Sweden)

    Wu GH


    Full Text Available Guo Hao Wu,1 Jian Gao,2 Chun Yan Ji,2 Lorenzo Pradelli,3 Qiu Lei Xi,1 Qiu Lin Zhuang1 1Department of General Surgery, 2Department of Nutrition, Zhongshan Hospital, Fudan University, Shanghai, People's Republic of China; 3AdRes Health Economics and Outcomes Research, Piazza Carlo Emanuele II, Torino, Italy Background and objectives: Clinical evidence supports the use of omega-3 polyunsaturated fatty acid (PUFA-enriched lipid emulsions in place of standard lipid emulsions in parenteral nutrition (PN for intensive care unit (ICU patients, but uptake may be limited by higher costs. We compared clinical and economic outcomes for these two types of lipid emulsion in the Chinese ICU setting. Methods: We developed a pharmacoeconomic discrete event simulation model, based on efficacy data from an international meta-analysis and patient characteristics, resource consumption, and unit costs from a Chinese institutional setting. Probabilistic sensitivity analyses were undertaken to assess the effects of uncertainty around input parameters. Model predictive validity was assessed by comparing results with data observed in a patient subset not used in the modeling. Results: The model predicted that omega-3 PUFA-enriched emulsion (Omegaven® 10% fish oil emulsion would dominate standard lipid emulsions, with better clinical outcomes and lower overall health care costs (mean savings ~10,000 RMB, mainly as a result of faster recovery and shorter hospital stay (by ~6.5 days. The external validation process confirmed the reliability of the model predictions. Conclusion: Omega-3 PUFA-enriched lipid emulsions improved clinical outcome and decreased overall costs in Chinese ICU patients requiring PN. Keywords: omega-3 PUFA-enriched lipids, ICU patients, total costs, microsimulation, external validation, length of hospital stay

  1. Observations on the 2016 World Congress on Continuing Professional Development: Advancing Learning and Care in the Health Professions. (United States)

    Turco, Mary G; Baron, Robert B


    The 2016 World Congress on Continuing Professional Development: Advancing Learning and Care in the Health Professions took place in San Diego, California, March 17-19, 2016. Hosts were the Association for Hospital Medical Education (AHME), Alliance for Continuing Education in the Health Professionals (ACEhp), and Society for Academic Continuing Medical Education (SACME). The target audience was the international community working to improve medical (CME), nursing (CNE), pharmacy (CPE), and interprofessional (CIPE) continuing education (CE) and continuing professional development (CPD). Goals included: addressing patients' concerns and needs; advancing global medical and interprofessional health sciences education; utilizing learning to address health disparities; and promoting international cooperation. The five keynote speakers were: patient advocate Alicia Cole ("Why What We Do Matters: The Patients Voice"); linguist Lorelei Lingard ("Myths about Healthcare Teamwork and Their Implications for How We Understand Competence"); futurist and philosopher Alex Jadad ("What Do We Need to Protect at All Costs in the 21st Century?"); ethicist and change agent Zeke Emanuel ("Learn to Change: Teaching Toward a Shifting Healthcare Horizon"); and technology innovator Stephen Downes ("From Individual to Community: The Learning Is in the Doing"). Organizers announced the new Dave Davis Distinguished Award for Excellence in Mentorship in Continuing Professional Development to honor the career of David Davis, MD, in CME/CPD scholarship in Canada, the United States, and beyond. Participants valued the emphasis on interprofessional education and practice, the importance of integrating the patient voice, the effectiveness of flipped classroom methods, and the power of collective competency theories. Attendee-respondents encouraged Congress planners to continue to strive for a broad global audience and themes of international interest.

  2. Joseph Conrad's tormented Rescue (fantasy). (United States)

    Freedman, William


    Joseph Conrad was a notoriously tormented writer for whom the creative act was often a punishment severe enough to drive him into paralyzing depressions that delayed the completion of his novels, sometimes for years. By far the most agonizing of these projects was The Rescue, a novel he began in 1898, abandoned a year later, tried unsuccessfully to continue several times over the next two decades, but was only able to resume in 1918 and to complete, after another tortured two-year struggle, in 1920. An explanation for this incapacity, that is powerfully suggested by the novel's evocative title and perhaps unintentionally ironic subtitle (A Romance of the Shallows) has not yet been explored. Using Freud's 1910 essay on the rescue fantasy, "Contributions to the Psychology of Love: A Special Type of Choice of Object Made by Men," and Emanuel Berman's instructive revision and expansion of the concept in his 2003 American Imago essay, "Ferenczi, Rescue, and Utopia," I argue that a substantial explanation for Conrad's tormented history with The Rescue is ascribable to its quite remarkably faithful treatment of a rescue fantasy with deep and disabling resonance for its author. More specifically, the difficulty was compounded by the novel's dramatization of the soul-crushing conflict between two such fantasies: one in the service of the masculine ideal of unflinching dedication to a heroic purpose, the other promising satisfaction to the equally potent demands of emotional and sexual desire. Features of Conrad's narrative fit so tightly and consistently with the theory as Freud (and Abraham) proposed and as Berman elaborated it that The Rescue offers itself as one of those rare and reinforcing instances wherein the literary text seems to validate the psychoanalytic theory at least as persuasively as the theory "understands" the text.

  3. Use of Twitter Polls to Determine Public Opinion Regarding Content Presented at a Major National Specialty Society Meeting. (United States)

    Rosenkrantz, Andrew B; Hawkins, C Matthew


    The aim of this study was to evaluate the feasibility of using Twitter polls to assess public opinion regarding session content at a national specialty society meeting. Twitter polls allow users to embed multiple-choice questions within tweets and automatically aggregate responses. Two radiologists attending the 2016 annual meeting of the ACR posted a Twitter poll containing the hashtag #ACR2016 during 10 meeting sessions addressing socioeconomics/advocacy, patient experience, and social media/informatics (20 polls total). Each poll contained a question asking for an opinion regarding the session's content. Polls were open for responses for 24 hours. The average number of responses per poll was significantly higher for the user with the larger number of Twitter followers (24.3 ± 14.4 versus 11.2 ± 9.8, P = .015). A total of 57% of respondents agreed that radiologists' payments should shift to value-based payments, and 86% agreed that radiologists should routinely survey their patients to monitor quality; however, 83% disagreed with basing physician payments on patient satisfaction scores. A total of 85% disagreed that the artificial intelligence supercomputer Watson will entirely replace radiologists. A total of 76% agreed that social media can drive business at less cost than standard marketing. A total of 56% agreed with the direction of the ACR's advocacy and regulatory efforts, whereas 74% considered the ACR's advocacy efforts to be moderately or very useful for their practice. A total of 50% planned to change their practice on the basis of keynote remarks by Dr Ezekiel Emanuel. Twitter polls provide a free and easy infrastructure to potentially capture global public sentiment during the course of a medical society meeting. Their use may enrich and promote discussions of key session content. Copyright © 2016 American College of Radiology. Published by Elsevier Inc. All rights reserved.

  4. The 'over-researched community': An ethics analysis of stakeholder views at two South African HIV prevention research sites. (United States)

    Koen, Jennifer; Wassenaar, Douglas; Mamotte, Nicole


    Health research in resource-limited, multi-cultural contexts raises complex ethical concerns. The term 'over-researched community' (ORC) has been raised as an ethical concern and potential barrier to community participation in research. However, the term lacks conceptual clarity and is absent from established ethics guidelines and academic literature. In light of the concern being raised in relation to research in low- and middle-income countries (LMICs), a critical and empirical exploration of the meaning of ORC was undertaken. Guided by Emanuel et al.'s (2004) eight principles for ethically sound research in LMICs, this study examines the relevance and meaning of the terms 'over-research' and 'over-researched community' through an analysis of key stakeholder perspectives at two South African research sites. Data were collected between August 2007 and October 2008. 'Over-research' was found to represent a conglomeration of ethical concerns often used as a proxy for standard research ethics concepts. 'Over-research' seemed fundamentally linked to disparate positions and perspectives between different stakeholders in the research interaction, arising from challenges in inter-stakeholder relationships. 'Over-research' might be interpreted to mean exploitation. However, exploitation itself could mean different things. Using the term may lead to obscured understanding of real or perceived ethical concerns, making it difficult to identify and address the underlying concerns. It is recommended that the term be carefully and critically interrogated for clarity when used in research ethics discourse. Because it represents other legitimate concerns, it should not be dismissed without careful exploration. Copyright © 2017 Elsevier Ltd. All rights reserved.

  5. Probabilistic Mapping of Storm-induced Coastal Inundation for Climate Change Adaptation (United States)

    Li, N.; Yamazaki, Y.; Roeber, V.; Cheung, K. F.; Chock, G.


    Global warming is posing an imminent threat to coastal communities worldwide. Under the IPCC RCP8.5 scenario, we utilize hurricane events downscaled from a CMIP5 global climate model using the stochastic-deterministic method of Emanuel (2013, Proc. Nat. Acad. Sci.) in a pilot study to develop an inundation map with projected sea-level rise for the urban Honolulu coast. The downscaling is performed for a 20-year period from 2081 to 2100 to capture the ENSO, which strongly influences the hurricane activity in the Pacific. A total of 50 simulations provide a quasi-stationary dataset of 1000 years for probabilistic analysis of the flood hazards toward the end of the century. We utilize the meta-model Hakou, which is based on precomputed hurricane scenarios using ADCIRC, SWAN, and a 1D Boussinesq model (Kennedy et al., 2012, Ocean Modelling), to estimate the annual maximum inundation along the project coastline at the present sea level. Screening of the preliminary results identifies the most severe three events for detailed inundation modeling using the package of Li et al. (2014, Ocean Modelling) at the projected sea level. For each event, the third generation spectral model WAVEWATCH III of Tolman (2008, Ocean Modelling) provides the hurricane waves and the circulation model NEOWAVE of Yamazaki et al. (2009, 2011, Int. J. Num. Meth. Fluids) computes the surge using a system of telescopic nested grids from the open ocean to the project coastline. The output defines the boundary conditions and initial still-water elevation for computation of phase-resolving surf-zone and inundation processes using the 2D Boussinesq model of Roeber and Cheung (2012, Coastal Engineering). Each computed inundation event corresponds to an annual maximum, and with 1000 years of data, has an occurrence probability of 0.1% in a given year. Barring the tail of the distribution, aggregation of the three computed events allow delineation of the inundation zone with annual exceedance probability

  6. PREFACE: 12th High-Tech Plasma Processes Conference (HTPP-12) (United States)

    Gleizes, Alain; Ghedini, Emanuele; Gherardi, Matteo; Sanibondi, Paolo; Dilecce, Giorgio


    organizing committee, the organizing secretariat and the financial support from the conference sponsors that allowed the success of HTPP-12. The Editors of the HTPP 12 Proceedings Professor Alain Gleizes (head of the ISC) Dr Emanuele Ghedini Dr Matteo Gherardi Dr Paolo Sanibondi Dr Giorgio Dilecce Bologna, 30 October 2012

  7. PREFACE: SQM2007 International Conference on Strangeness in Quark Matter (United States)

    Šafařík, Karel; Šándor, Ladislav; Tomášik, Boris


    professional work in preparing and running the conference. We thank all the speakers and session chairpersons for their active contribution to the inspiring scientific atmosphere at the conference. We also thank Emanuele Quercigh for an enlightening after-dinner speech. Finally, it is our pleasure to express thanks to all members of the SQM International Advisory Committee for their valuable input to the scientific programme and conference arrangement.

  8. Some lessons and thoughts from development of an old-fashioned high-resolution atmospheric general circulation model (United States)

    Ohfuchi, Wataru; Enomoto, Takeshi; Yoshioka, Mayumi K.; Takaya, Koutarou


    Some high-resolution simulations with a conventional atmospheric general circulation model (AGCM) were conducted right after the first Earth Simulator started operating in the spring of 2002. More simulations with various resolutions followed. The AGCM in this study, AFES (Agcm For the Earth Simulator), is a primitive equation spectral transform method model with a cumulus convection parameterization. In this presentation, some findings from comparisons between high and low-resolution simulations, and some future perspectives of old-fashioned AGCMs will be discussed. One obvious advantage of increasing resolution is capability of resolving the fine structures of topography and atmospheric flow. By increasing resolution from T39 (about 320 km horizontal grid interval) to T79 (160 km), to T159 (80 km) to T319 (40 km), topographic precipitation over Japan becomes increasingly realistic. This feature is necessary for climate and weather studies involving both global and local aspects. In order to resolve submesoscale (about 100 km horizontal scale) atmospheric circulation, about 10-km grid interval is necessary. Comparing T1279 (10 km) simulations with T319 ones, it is found that, for example, the intensity of heavy rain associated with Baiu front and the central pressure of typhoon become more realistic. These realistic submesoscale phenomena should have impact on larger-sale flow through dynamics and thermodynamics. An interesting finding by increasing horizontal resolution of a conventional AGCM is that some cumulus convection parameterizations, such as Arakawa-Schubert type scheme, gradually stop producing precipitation, while some others, such as Emanuel type, do not. With the former, the grid condensation increases with the model resolution to compensate. Which characteristics are more desirable is arguable but it is an important feature one has to consider when developing a high-resolution conventional AGCM. Many may think that conventional primitive equation

  9. The relevance of social contexts and social action in reducing substance use and victimization among women participating in an HIV prevention intervention in Cape Town, South Africa

    Directory of Open Access Journals (Sweden)

    Reed E


    Full Text Available Elizabeth Reed,1 Andrea N Emanuel,2 Bronwyn Myers,3,4 Kim Johnson,3 Wendee M Wechsberg2,5–7 1George Washington University School of Public Health, Department of Prevention and Community Health, Washington, DC, USA; 2RTI International, Research Triangle Park, NC, USA; 3Alcohol and Drug Abuse Research Unit, Medical Research Council, Cape Town, South Africa; 4Department of Psychiatry and Mental Health, University of Cape Town, Cape Town, South Africa; 5Gillings Global School of Public Health, University of North Carolina, Chapel Hill, NC, USA; 6Psychology in the Public Interest, North Carolina State University, NC, USA; 7Psychiatry and Behavioral Sciences, Duke University School of Medicine, NC, USA Objectives: To examine qualitatively how women's social context and community mobilization (eg, mobilizing women to take social action and engaging their community in social change influence substance use abstinence and victimization among women participating in a human immunodeficiency virus (HIV intervention in Cape Town, South Africa. Methods: Thirty women who had participated in a randomized controlled trial of a group-delivered intervention to address substance use, gender-based violence, and associated risk for HIV (The Women's Health CoOp were selected to participate in semi-structured interviews about their perceived impact of the intervention on their substance use and exposure to victimization. The Women's CoOp intervention involved creating a new positive social environment for women within a group setting that also fostered women's social action (eg, educating peers or family members in the community. Interviews were analyzed using content analysis and coded to examine women's descriptions of social contexts and social action, and the influence of these on women's substance use abstinence and exposure to victimization. Results: Social support (eg, via program staff and other participants and social action (eg, engaging others in the

  10. Cost of human immunodeficiency virus infection in Italy, 2007–2009: effective and expensive, are the new drugs worthwhile?

    Directory of Open Access Journals (Sweden)

    Rizzardini G


    Full Text Available Giuliano Rizzardini,1 Umberto Restelli,2 Paolo Bonfanti,3 Emanuele Porazzi,2 Elena Ricci,1 Emanuela Foglia,2 Laura Carenzi,1 Davide Croce21First Infectious Diseases Department, "Luigi Sacco" Hospital, Milan; 2Centre for Research on Health Economics, Social, and Health Care Management, Università Carlo Cattaneo, Castellanza; 3Infectious Diseases Department, "Alessandro Manzoni" Hospital, Lecco, ItalyBackground: In recent years, the increased efficacy and effectiveness of antiretroviral treatment has led to longer survival of patients infected with human immunodeficiency virus (HIV, but has also raised the question of what happens to consumption of resources. Early highly active antiretroviral treatment (HAART, management of hepatitis C virus (HCV coinfection, and expensive newly marketed drugs may affect the economic sustainability of treatment from the point of view of the National Healthcare Services. The present study aimed to provide information on the economic burden of HIV-positive patients resident in the Lombardy region using a three-year time horizon.Methods: This was a retrospective, observational, budget impact study, based on information collected for the period 2007–2009, including hospitalizations, outpatient services, and HAART and non-HAART drug utilization. Patients with confirmed HIV infection, aged ≥ 18 years, resident in the Lombardy region, and followed at the "L Sacco" Hospital in Milan from 2007 to 2009 were eligible.Results: A total of 483 patients (mean age 44.1 years were included in the study. The mean CD4+ cell count increased over the study period from 462 ± 242 cells/mm3 in 2007, to 513 ± 267 cells/mm3 in 2008, to 547 ± 262 cells/mm3 in 2009. In total, 162 subjects (33.5% were coinfected with HCV. Hospitalizations and HAART costs increased from 2007 to 2009, whereas outpatient visits and non-HAART drug costs decreased slightly over time. The total cost increase was also significant when limiting the analysis

  11. Operative and nonoperative management for renal trauma: comparison of outcomes. A systematic review and meta-analysis

    Directory of Open Access Journals (Sweden)

    Mingoli A


    Full Text Available Andrea Mingoli,1,2 Marco La Torre,1,2 Emanuele Migliori,1,2 Bruno Cirillo,1,2 Martina Zambon,1,2 Paolo Sapienza,1,2 Gioia Brachini1,2 1Emergency Department, 2Department of Surgery P Valdoni, Policlinico Umberto I, Sapienza University, Rome, Italy Introduction: Preservation of kidney and renal function is the goal of nonoperative management (NOM of renal trauma (RT. The advantages of NOM for minor blunt RT have already been clearly described, but its value for major blunt and penetrating RT is still under debate. We present a systematic review and meta-analysis on NOM for RT, which was compared with the operative management (OM with respect to mortality, morbidity, and length of hospital stay (LOS. Methods: The Preferred Reporting Items for Systematic Reviews and Meta-analyses statement was followed for this study. A systematic search was performed on Embase, Medline, Cochrane, and PubMed for studies published up to December 2015, without language restrictions, which compared NOM versus OM for renal injuries. Results: Twenty nonrandomized retrospective cohort studies comprising 13,824 patients with blunt (2,998 or penetrating (10,826 RT were identified. When all RT were considered (American Association for the Surgery of Trauma grades 1–5, NOM was associated with lower mortality and morbidity rates compared to OM (8.3% vs 17.1%, odds ratio [OR] 0.471; 95% confidence interval [CI] 0.404–0.548; P<0.001 and 2% vs 53.3%, OR 0.0484; 95% CI 0.0279–0.0839, P<0.001. Likewise, NOM represented the gold standard treatment resulting in a lower mortality rate compared to OM even when only high-grade RT was considered (9.1% vs 17.9%, OR 0.332; 95% CI 0.155–0.708; P=0.004, be they blunt (4.1% vs 8.1%, OR 0.275; 95% CI 0.0957–0.788; P=0.016 or penetrating (9.1% vs 18.1%, OR 0.468; 95% CI 0.398–0.0552; P<0.001. Conclusion: Our meta-analysis demonstrated that NOM for RT is the treatment of choice not only for AAST grades 1 and 2, but also for higher

  12. Modelling of the Nutrient Medium for Plants Cultivation in Spaceflight (United States)

    Nechitailo, Galina S.


    MODELLING OF THE NUTRIENT MEDIUM FOR PLANTS CULTIVATION IN SPACEFLIGHT Nechitajlo G.S.*, Rakhmetova A.A.**, Bogoslovskaja O.A.**, Ol'hovskay I.P.**, Glushchenko N.N.** *Emanuel Institute of Biochemical Physics of Russian Academy of Sciences (IBCP RAS) mail: **V.L. Talrose Institute for Energy Problems of Chemical Physics of Russian Academy of Science (INEPCP RAS) mail: nnglu@ The valuable life and fruitful activity of cosmonauts and researchers in conditions of spaceflights and prolonged work at space stations are only possible with creating life area providing fresh air, natural food, comfortable psychological conditions, etc. The solution of that problem under space conditions seems impossible without use of high nano- and biotechnologies for plants growth. A priority should be given not only to choose species of growth plants in space, but also to improve conditions for their growth which includes optimal nourishing components for plants, preparation of nutrient mediums, illumination and temperature. We are deeply convinced that just manipulations with growing conditions for cultivated plants, but not genes changes, is a guarantee of success in the decision of this problem. For improving the method of plants growing on the artificial nutrient medium with balanced content of components, being necessary for growth and development of plants, we added essential metal elements: Fe, Zn, Cu - in an electroneutral state in the form of nanoparticles instead of sulfates or other easily dissolving salts. Nanoparticulated metals are known to have a number of advantages in comparison with salts: metals in an electroneutral form are characterized with the prolonged and multifunctional action, low toxicity per se and appearing to be much below the toxicity of the same metals in the ionic forms, accumulation as a reserve being used in biotic dozes, active distribution in bodies and organs of plants and stimulation of vital processes. A high reactivity

  13. Colonic polyps: inheritance, susceptibility, risk evaluation, and diagnostic management

    Directory of Open Access Journals (Sweden)

    Emanuele Neri


    Full Text Available Emanuele Neri, Lorenzo Faggioni, Lorenzo Cini, Carlo BartolozziDiagnostic and Interventional Radiology, University of Pisa, Pisa, ItalyAbstract: Colorectal cancer (CRC is the third-ranked neoplasm in order of incidence and mortality, worldwide, and the second cause of cancer death in industrialized countries. One of the most important environmental risk factors for CRC is a Western-type diet, which is characterized by a low-fiber and high-fat content. Up to 25% of patients with CRC have a family history for CRC, and a fraction of these patients are affected by hereditary syndromes, such as familial adenomatous polyposis, Gardner or Turcot syndromes, or hereditary nonpolyposis colorectal cancer. The onset of CRC is triggered by a well-defined combination of genetic alterations, which form the bases of the adenoma-carcinoma sequence hypothesis and justify the set-up of CRC screening techniques. Several screening and diagnostic tests for CRC are illustrated, including rectosigmoidoscopy, optical colonoscopy (OC, double contrast barium enema (DCBE, and computed tomography colonography (CTC. The strengths and weaknesses of each technique are discussed. Particular attention is paid to CTC, which has evolved from an experimental technique to an accurate and mature diagnostic approach, and gained wide acceptance and clinical validation for CRC screening. This success of CTC is due mainly to its ability to provide cross-sectional analytical images of the entire colon and secondarily detect extracolonic findings, with minimal invasiveness and lower cost than OC, and with greater detail and diagnostic accuracy than DCBE. Moreover, especially with the advent and widespread availability of modern multidetector CT scanners, excellent quality 2D and 3D reconstructions of the large bowel can be obtained routinely with a relatively low radiation dose. Computer-aided detection systems have also been developed to assist radiologists in reading CTC examinations


    Directory of Open Access Journals (Sweden)

    Dwi Tatak Subagiyo


    Full Text Available Buku ini banyak diisi oleh istilah-istilah filsafat umum, tetapi penekanannya pada kajian yang mengarah pada filsafat hukum. Dalam buku tersebut berisikan retributivisme atau teori proporsionalitas dengan mengandalkan teori yang dikemukakan oleh Emanuel Kant dan Hegel. Di samping itu juga disoroti teori utilitarisme atau teori konsekuensialisme yang dibahas secara mendalam dan terstruktur oleh Jeramy Bentham. Dalam masa dan era globalisasi ini negara kita telah dilanda berbagai gejolak, baik dalam bidang ekonomi, sosial, politik, budaya dan hukum. Oleh karena itu untuk membantu masyarakat dalam memecahkan sebagian dari kekecewaannya dibutuhkan rujukan-rujukan yang nantinya akan dapat diangkat sebagai pedoman jika perlu dan dapat berfaedah untuk mengatasi kebuntuan tersebut. Memang tidak dapat dipungkiri bahwa untuk membaca buku ini diperlukan beberapa penafsiran dan interprestasi yang sangat mendalam, karena tanpa adanya alat-alat tcrsebut tidak akan dapat mendapatkan solusi bagi pcnggunaan hukuman yang nantinya dapat sedikit banyak meningkatkan supremasi hukum yang hingga kini kian merosot di mata masyarakat kita. Kajian etika memang tidak dapat dilepaskan dari adanya moral seseorang untuk mengikuti segala bidang. Sekarang ini hanyalah yang diperlukan adalah moral dan etika supaya kita tidak terpuruk dalam pola-pola anarkisme, sehingga sulit untuk mengadakan kontrol. Kontrol dan pengawasan dapat dilakukan oleh setiap orang untuk menegakkan normalisasi dalam kehidupan bermasyarakat. Sulit untuk memisahkan antara etik dan moral karena keduanya bagaikan dua sisi mata uang yang tidak dapat dipisahkan, berarti kedua aspek tersebut saling berketergantungan. Buku yang berjumlah halaman 110 ini mencerminkan bahwa teori-teori yang dikemukakan oleh para filsufini tidak lain adalah untuk memberikan kontribusi pada negara, khususnya dalam cara untuk penegakan hukum suatu negara. Tetapi perlu diketahui kepada para pembaca untuk berhati-hati dalam membaca

  15. Duration of remission after halving of the etanercept dose in patients with ankylosing spondylitis: a randomized, prospective, long-term, follow-up study

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    Nannini C


    Full Text Available Fabrizio Cantini, Laura Niccoli, Emanuele Cassarà, Olga Kaloudi, Carlotta NanniniDivision of Rheumatology, Misericordia e Dolce Hospital, Prato, ItalyBackground: The aim of this study was to evaluate the proportion of patients with ankylosing spondylitis maintaining clinical remission after reduction of their subcutaneous etanercept dose to 50 mg every other week compared with that in patients receiving etanercept 50 mg weekly.Methods: In the first phase of this randomized, prospective, follow-up study, all biologic-naïve patients identified between January 2005 and December 2009 as satisfying the modified New York clinical criteria for ankylosing spondylitis treated with etanercept 50 mg weekly were evaluated for disease remission in January 2010. In the second phase, patients meeting the criteria for remission were randomized to receive subcutaneous etanercept as either 50 mg weekly or 50 mg every other week. The randomization allocation was 1:1. Remission was defined as Bath Ankylosing Spondylitis Disease Activity Index < 4, no extra-axial manifestations of peripheral arthritis, dactylitis, tenosynovitis, or iridocyclitis, and normal acute-phase reactants. The patients were assessed at baseline, at weeks 4 and 12, and every 12 weeks thereafter. The last visit constituted the end of the follow-up.Results: During the first phase, 78 patients with ankylosing spondylitis (57 males and 21 females, median age 38 years, median disease duration 12 years were recruited. In January 2010, after a mean follow-up of 25 ± 11 months, 43 (55.1% patients achieving clinical remission were randomized to one of the two treatment arms. Twenty-two patients received etanercept 50 mg every other week (group 1 and 21 received etanercept 50 mg weekly (group 2. At the end of follow-up, 19 of 22 (86.3% subjects in group 1 and 19 of 21 (90.4% in group 2 were still in remission, with no significant difference between the two groups. The mean follow-up duration in group

  16. Collaborative partnership and the social value of clinical research: a qualitative secondary analysis. (United States)

    Nurmi, Sanna-Maria; Halkoaho, Arja; Kangasniemi, Mari; Pietilä, Anna-Maija


    Protecting human subjects from being exploited is one of the main ethical challenges for clinical research. However, there is also a responsibility to protect and respect the communities who are hosting the research. Recently, attention has focused on the most efficient way of carrying out clinical research, so that it benefits society by providing valuable research while simultaneously protecting and respecting the human subjects and the communities where the research is conducted. Collaboration between partners plays an important role and that is why we carried out a study to describe how collaborative partnership and social value are emerging in clinical research. A supra-analysis design for qualitative descriptive secondary analysis was employed to consider a novel research question that pertained to nurse leaders' perceptions of ethical recruitment in clinical research and the ethics-related aspects of clinical research from the perspective of administrative staff. The data consisted of two separate pre-existing datasets, comprising 451 pages from 41 interviews, and we considered the research question by using deductive-inductive content analysis with NVivo software. A deductive analysis matrix was generated on the basis of two requirements, namely collaborative partnership and social value, as presented in An Ethical Framework for Biomedical Research by Emanuel et al. The findings showed that collaborative partnership was a cornerstone for ethical clinical research and ways to foster inter-partner collaboration were indicated, such as supporting mutual respect and equality, shared goals and clearly defined roles and responsibilities. In addition, the social value of clinical research was an important precondition for ethical clinical research and its realisation required the research partners to demonstrate collaboration and shared responsibility during the research process. However, concerns emerged that the multidimensional meaning of clinical research for

  17. Biological species is the only possible form of existence for higher organisms: the evolutionary meaning of sexual reproduction

    Directory of Open Access Journals (Sweden)

    Shcherbakov Victor P


    -evolutionary consequence of the sexuality is evident from the fact that the genotypes of the individuals with an enhanced competitiveness are not transmitted to the next generation. Instead, after mating with "ordinary" individuals, these genotypes scatter and rearrange in new gene combinations, thus preventing the winner from exploiting the success. Reviewers This article was reviewed by Pierre Antoine Pontarotti, Michael T. Ghiselin (nominated by Dr. Juergen Brosius and Emanuel Tannenboum (nominated by Dr. Doron Lancet

  18. Update on diode-pumped solid-state laser experiments for inertial fusion energy

    International Nuclear Information System (INIS)

    Marshall, C.; Smith, L.; Payne, S.


    The authors have completed the initial phase of the diode-pumped solid-state laser (DPSSL) experimental program to validate the expected pumping dynamics and extraction cross-sections of Yb 3+ -doped Sr 5 (PO 4 ) 3 F (Yb:S-FAP) crystals. Yb:S-FAP crystals up to 25 x 25 x 175 mm in size have been grown for this purpose which have acceptable loss characteristics ( 2 ). The saturation fluence for pumping has been measured to be 2.2 J/cm 2 using three different methods based on either the spatial, temporal, or energy transmission properties of a Yb:S-FAP rod. The small signal gain under saturated pumping conditions was measured. These measurements imply an emission cross section of 6.0 x 10 -20 cm 2 that falls within error bars of the previously reported value of 7.3 x 10 -20 cm 2 , obtained from purely spectroscopic techniques. The effects of radiation trapping on the emission lifetime have been quantified. The long lifetime of Yb:S-FAP has beneficial effects for diode-pumped amplifier designs, relative to materials with equivalent cross sections but shorter lifetimes, in that less peak pump intensity is required (thus lower diode costs) and that lower spontaneous emission rates lead to a reduction in amplified spontaneous emission. Consequently, up to 1.7 J/cm 3 of stored energy density was achieved in a 6x6x44 mm Yb:S-FAP amplifier rod; this stored energy density is large relative to typical flashlamp-pumped Nd:glass values of 0.3 to 0.5 J/cm 3 . A 2.4 kW peak power InGaAs diode array has been fabricated by Beach, Emanuel, and co-workers which meets the central wavelength, bandwidth, and energy specifications for the author's immediate experiments. These results further increase their optimism of being able to produce a ∼ 10% efficient diode-pumped solid state laser for inertial fusion energy

  19. Representation of monsoon intraseasonal oscillations in regional climate model: sensitivity to convective physics

    KAUST Repository

    Umakanth, U.


    The aim of the study is to evaluate the performance of regional climate model (RegCM) version 4.4 over south Asian CORDEX domain to simulate seasonal mean and monsoon intraseasonal oscillations (MISOs) during Indian summer monsoon. Three combinations of Grell (G) and Emanuel (E) cumulus schemes namely, RegCM-EG, RegCM-EE and RegCM-GE have been used. The model is initialized at 1st January, 2000 for a 13-year continuous simulation at a spatial resolution of 50 km. The models reasonably simulate the seasonal mean low level wind pattern though they differ in simulating mean precipitation pattern. All models produce dry bias in precipitation over Indian land region except in RegCM-EG where relatively low value of dry bias is observed. On seasonal scale, the performance of RegCM-EG is more close to observation though it fails at intraseasonal time scales. In wave number-frequency spectrum, the observed peak in zonal wind (850 hPa) at 40–50 day scale is captured by all models with a slight change in amplitude, however, the 40–50 day peak in precipitation is completely absent in RegCM-EG. The space–time characteristics of MISOs are well captured by RegCM-EE over RegCM-GE, however it fails to show the eastward propagation of the convection across the Maritime Continent. Except RegCM-EE all other models completely underestimates the moisture advection from Equatorial Indian Ocean onto Indian land region during life-cycle of MISOs. The characteristics of MISOs are studied for strong (SM) and weak (WM) monsoon years and the differences in model performances are analyzed. The wavelet spectrum of rainfall over central India denotes that, the SM years are dominated by high frequency oscillations (period <20 days) whereas little higher periods (>30 days) along with dominated low periods (<20 days) observed during WM years. During SM, RegCM-EE is dominated with high frequency oscillations (period <20 days) whereas in WM, RegCM-EE is dominated with periods >20

  20. Physically-based Assessment of Tropical Cyclone Damage and Economic Losses (United States)

    Lin, N.


    Estimating damage and economic losses caused by tropical cyclones (TC) is a topic of considerable research interest in many scientific fields, including meteorology, structural and coastal engineering, and actuarial sciences. One approach is based on the empirical relationship between TC characteristics and loss data. Another is to model the physical mechanism of TC-induced damage. In this talk we discuss about the physically-based approach to predict TC damage and losses due to extreme wind and storm surge. We first present an integrated vulnerability model, which, for the first time, explicitly models the essential mechanisms causing wind damage to residential areas during storm passage, including windborne-debris impact and the pressure-debris interaction that may lead, in a chain reaction, to structural failures (Lin and Vanmarcke 2010; Lin et al. 2010a). This model can be used to predict the economic losses in a residential neighborhood (with hundreds of buildings) during a specific TC (Yau et al. 2011) or applied jointly with a TC risk model (e.g., Emanuel et al 2008) to estimate the expected losses over long time periods. Then we present a TC storm surge risk model that has been applied to New York City (Lin et al. 2010b; Lin et al. 2012; Aerts et al. 2012), Miami-Dade County, Florida (Klima et al. 2011), Galveston, Texas (Lickley, 2012), and other coastal areas around the world (e.g., Tampa, Florida; Persian Gulf; Darwin, Australia; Shanghai, China). These physically-based models are applicable to various coastal areas and have the capability to account for the change of the climate and coastal exposure over time. We also point out that, although made computationally efficient for risk assessment, these models are not suitable for regional or global analysis, which has been a focus of the empirically-based economic analysis (e.g., Hsiang and Narita 2012). A future research direction is to simplify the physically-based models, possibly through

  1. Joint projections of sea level and storm surge using a flood index (United States)

    Little, C. M.; Lin, N.; Horton, R. M.; Kopp, R. E.; Oppenheimer, M.


    Capturing the joint influence of sea level rise (SLR) and tropical cyclones (TCs) on future coastal flood risk poses significant challenges. To address these difficulties, Little et al. (2015) use a proxy of tropical cyclone activity and a probabilistic flood index that aggregates flood height and duration over a wide area (the US East and Gulf coasts). This technique illuminates the individual impacts of TCs and SLR and their correlation across different coupled climate models. By 2080-2099, changes in the flood index relative to 1986-2005 are substantial and positively skewed: a 10th-90th percentile range of 35-350x higher for a high-end business-as-usual emissions scenario (see figure). This aggregated flood index: 1) is a means to consistently combine TC-driven storm surges and SLR; 2) provides a more robust description of historical surge-climate relationships than is available at any one location; and 3) allows the incorporation of a larger climate model ensemble - which is critical to uncertainty characterization. It does not provide a local view of the complete spectrum of flood severity (i.e. return curves). However, alternate techniques that provide localized return curves (e.g. Lin et al., 2012) are computationally intensive, limiting the set of large-scale climate models that can be incorporated, and require several linked statistical and dynamical models, each with structural uncertainties that are difficult to quantify. Here, we present the results of Little et al. (2015) along with: 1) alternate formulations of the flood index; 2) strategies to localize the flood index; and 3) a comparison of flood index projections to those provided by model-based return curves. We look to this interdisciplinary audience for feedback on the advantages and disadvantages of each tool for coastal planning and decision-making. Lin, N., K. Emanuel, M. Oppenheimer, and E. Vanmarcke, 2012: Physically based assessment of hurricane surge threat under climate change. Nature

  2. Epidemiology and treatment of mood disorders in a day hospital setting from 1996 to 2007: an Italian study

    Directory of Open Access Journals (Sweden)

    Luca M


    Full Text Available Maria Luca,1 Giuseppa Prossimo,1 Vincenzo Messina,1 Antonina Luca,2 Salvatore Romeo,1 Carmela Calandra11Department of Medical and Surgery Specialties, Psychiatry Unit, 2Department of Neuroscience, University Hospital Policlinico-Vittorio Emanuele, Catania, Sicily, ItalyBackground: The present study aimed: to assess prescribing patterns in the treatment of major depression, bipolar disorder type I, cyclothymia, and dysthymia from 1996 to 2007 in a day hospital setting; to evaluate the prevalence of the above-mentioned mood disorders and gender distribution; and to relate familiality, comorbidity, and marital status to each diagnosis.Methods: Medical records for 777 day hospital patients with a diagnosis of major depression, bipolar disorder type I, cyclothymia, or dysthymia were grouped into two 6-year periods so as to compare the prescribing patterns of tricyclic antidepressants, selective serotonin reuptake inhibitors, noradrenergic reuptake inhibitors, serotonin and norepinephrine reuptake inhibitors, noradrenergic and specific serotonergic antidepressants, first-generation antipsychotics, second-generation antipsychotics, and mood stabilizers. Gender, prevalence, familiality, comorbidity, and marital status were related to each diagnosis.Results: The most common mood disorder, with a female preponderance, was major depression, regardless of marital status. High percentages of familiality and comorbidity were found for major depression, while a reduction was found in the utilization of tricyclic antidepressants. There was no statistically significant difference in rates of prescription of selective serotonin reuptake inhibitors and noradrenergic reuptake inhibitors, but some irregularities were found upon evaluating each diagnosis (eg, increased utilization of these agents in dysthymia and major depression, respectively. There was an increase in prescriptions for serotonin and norepinephrine reuptake inhibitors, but no marked differences in

  3. Ecuadorian Cancer Patients' Preference for Information and Communication Technologies: Cross-Sectional Study. (United States)

    Cherrez Ojeda, Ivan; Vanegas, Emanuel; Torres, Michell; Calderón, Juan Carlos; Calero, Erick; Cherrez, Annia; Felix, Miguel; Mata, Valeria; Cherrez, Sofia; Simancas, Daniel


    investigate how to develop and promote ICT-based resources more effectively to engage the outcomes of cancer patients. The widespread use of ICTs narrows the gap between cancer patients with restricted socioeconomic conditions and those with wealth and easily available technological means, thereby opening up new possibilities in low-income countries. ©Ivan Cherrez Ojeda, Emanuel Vanegas, Michell Torres, Juan Carlos Calderón, Erick Calero, Annia Cherrez, Miguel Felix, Valeria Mata, Sofia Cherrez, Daniel Simancas. Originally published in the Journal of Medical Internet Research (, 20.02.2018.

  4. The first urban plan of Uzice from 1863.

    Directory of Open Access Journals (Sweden)

    Kuzović Duško


    Full Text Available Urban plan for Uzice from 1863. started urban reforming of settlement. Historical events in 1862. set the basis: great fire and emigration of Turks from the city which reduced number from 5700 to 2490 inhabitants. At the same time, financial capacity of population weakened and that affected to dynamics of reconstruction. Sketch of current state from 1863. represents first geodetic record of the town. It provides important information about town state during Turkish occupation. On sketch of current state after the fire are seen unequal width winding streets, blocks with irregular borders, streams flowing freely through town, and, in the town center, a large cemetery which divides the town and prevents further development. According to the sketch was made the First regulation proposal on May 1863. (eng. Emanuel Shefel which included identical surface as area destroyed in the fire. With this plan cemetery located in center was abolished, regulation of river Djetinja and steam Uremovac was planned, formed two blocks at expense of river regulation, street routes were straightened, street axle fractures were planned only in areas of intersections, block boundaries realigned, blocks got proper geometry, and around the church and district office was formed a town market from which poured out the main street - carsija. Problems of this proposalwere that it envisaged small number of town markets, in relation to economic importance of the town and inappropriate main street solution. In order to help in rewriting the plan in the town were sent engineers Josip Klinar (from Cacak and Joseph Veseli (from Loznica. Together with E. Sefel they have made Second plan proposal: thay have expanded plan intervention to north (Military Circle, to west (stream Kostica, on cemetary space were formed two blocks and Knez Milos Market, on west side the block where was madrassa was reduced and school building was set on the regulatory line and thereby was formed Sveti Sava

  5. Relationships between convective asymmetry, imbalance and intensity in numerically simulated tropical cyclones

    Directory of Open Access Journals (Sweden)

    David A. Schecter


    Full Text Available This article examines the relationships between convective asymmetry (CA, imbalance and intensity in tropical cyclones (TCs that emerge from random winds on the periodic f-plane in a cloud-system-resolving numerical model. The model is configured with warm-rain microphysics and includes a basic parameterisation of long-wave radiation. Within the simulation set, the sea-surface temperature ranges from 26 to 32°C, and the Coriolis parameter f ranges from 10−5 to 10−4 s−1. The number of TCs that develop in a simulation increases rapidly with f and ranges from 1 to 18. Taken together, the simulations provide a diverse spectrum of vortices that can be used for a meaningful statistical study.Consistent with earlier studies, mature TCs with minimal asymmetry are found to have maximum wind speeds greater than the classic theoretical value derived by Emanuel under the assumptions of gradient-wind and hydrostatic balance. In a statistical sense, it is found that the degree of superintensity with respect to balance theory reliably decays with an increasing level of inner-core CA. It is verified that a more recent version of axisymmetric steady-state theory, revised to incorporate imbalance, provides a good approximation for the maximum (azimuthally averaged azimuthal wind speed V max when CA is relatively weak. More notably, this theory for axisymmetric vortices maintains less than 10% error as CA becomes comparable in magnitude to the symmetric component of inner-core convection. Above a large but finite threshold of CA, axisymmetric steady-state theory generally over-predicts V max. The underachievement of TCs in this parameter regime is shown to coincide with substantial violation of the theoretical assumption of slantwise convective neutrality in the main updraft of the basic state. Of further interest, a reliable curve-fit is obtained for the anticorrelation between a simple measure of CA and V max normalised to an estimate of its balanced

  6. Parenteral nutrition including an omega-3 fatty-acid-containing lipid emulsion for intensive care patients in China: a pharmacoeconomic analysis

    Directory of Open Access Journals (Sweden)

    Feng Y


    Full Text Available Yufei Feng,1 Chao Li,1 Tian Zhang,1 Lorenzo Pradelli2 1Department of Pharmacy, Beijing Hospital, National Center of Gerontology, Beijing, People’s Republic of China; 2AdRes Health Economics and Outcomes Research, Piazza Carlo Emanuele II, Torino, Italy Background/objectives: Parenteral nutrition (PN incorporating omega-3 fatty-acid-enriched lipid emulsions has been shown to be cost effective in Western populations. A pharmacoeconomic evaluation was performed within the Chinese intensive care unit (ICU setting. This assessed whether the additional acquisition cost of PN with omega-3 fatty-acid-enriched lipid emulsion (SMOFlipid vs standard PN was offset by improved clinical outcomes that can reduce subsequent costs. Materials and methods: A pharmacoeconomic discrete event simulation model was developed, based on an update to efficacy data from a previous international meta-analysis, with China-specific clinical and economic input parameters. Sensitivity analyses were undertaken to assess the effects of uncertainty around input parameters. Results: The model predicted that PN with an omega-3 fatty-acid-enriched lipid emulsion was more effective and less costly than PN with standard lipid emulsions for Chinese ICU patients, as follows: reduced length of overall hospital length of stay (19.48 vs 21.35 days, respectively, reduced length of ICU stay (5.03 vs 6.18 days, respectively, and prevention of 35.6% of nosocomial infections leading to a lower total cost per patient (¥47 189 [US $6937] vs ¥54 783 [US $8053], respectively. Additional treatment costs were offset by savings in overall hospital and ICU stay cost, and antibiotic cost, resulting in a mean cost saving of ¥7594 (US $1116 per patient. Sensitivity analyses confirmed the robustness of these findings. Conclusions: PN enriched with an omega-3 fatty-acid-containing lipid emulsion vs standard PN may be effective in reducing length of hospital and ICU stay and infectious complications in

  7. Letter from Stockholm. (United States)

    Johansson, Per Magnus


    Some of the ideas of Sigmund Freud were preceded in a literary form by the Swedish writer August Strindberg in the late 19th century. Psychoanalysis itself was introduced in Sweden about a decade into the 20th century by two rivalling pioneers, the doctors Emanuel af Geijerstam and Poul Bjerre. After a slow start, the Danish-Norwegian Psychoanalytical Society and the Finnish-Swedish Psychoanalytical Society were formed in 1934 in Stockholm. The same year, Ericastiftelsen [The Erica Foundation], a psychotherapeutic clinic for children, was founded by Hanna Bratt. Five years later, in 1939, also in Stockholm, the organization that was to become St. Lukasstiftelsen [The Saint Luke's Foundation] was founded. It has been, and still is, an association that has trained psychodynamic psychotherapists, with a focus on existential, religious and philosophical questions. Today, St. Luke's tries to be up-dated from an academic standpoint. During the Second World War, several important psychoanalysts came to Sweden, for example René de Monchy, Lajos and Edith Székely, and Stefi Pedersen. Ola Andersson's doctoral dissertation ("Studies in the Prehistory of Psychoanalysis", 1962) and the historian Gunnar Brandell's essay ("Freud, a Man of His Century", 1961) have had an international impact. In the last two decades, an authorized and carefully edited translation of Freud's collected works has been published by Natur och Kultur, and the history of psychoanalysis in Sweden has been written at the University of Gothenburg. As a result of a recent interest in the work of Jacques Lacan, and French psychoanalysis, philosophy and literature, the journal Psykoanalytisk Tid/Skrift was founded in 2002, in Gothenburg. Since 2011 the journal is called Arche. The largest organized group of psychoanalysts in Sweden today is the Swedish Psychoanalytical Association (SPAF), which has around 225 members. Since 2008, it no longer has the right to license psychotherapists, a situation which

  8. Permissive tolerance of the patent ductus arteriosus may increase the risk of Chronic Lung Disease

    Directory of Open Access Journals (Sweden)

    Kaempf JW


    Full Text Available Joseph W Kaempf,1 Robert Huston,2 YingXing Wu,1 Andrew J Kaempf,1 Lian Wang,1 Gary Grunkemeier,1 Rebecca Mischel,2 Howard Cohen,3 Bret Freitag41Providence St Vincent Medical Center, Portland, OR, 2Randall Children’s Hospital at Legacy Emanuel, Portland, OR, 3Salem Hospital, Salem, OR, 4Legacy Salmon Creek Hospital, Vancouver, WA, USAPurpose: Because early closure therapies of the patent ductus arteriosus (PDA have not been shown to confer benefit to premature infants, the authors’ four neonatal intensive care units adopted a less aggressive PDA management protocol.Study design: A before–after investigation in infants with PDAs born 501–1500 g. Era 1 (January 2005 to December 2007 featured traditional management with indomethacin and/or surgical ligation used early to close PDAs; Era 2 (January 2008 to June 2009 featured fluid restriction and watchful waiting for PDA closure, limiting indomethacin or surgical ligation to only those infants with large PDAs needing significant respiratory support.Results: Era 2 infants (n = 129, mean ± standard deviation 27 ± 2 weeks received less and later indomethacin and less Day 1–28 total fluids as compared to Era 1 infants (n = 240, mean ± standard deviation 27 ± 2 weeks. The Chronic Lung Disease (CLD rate was higher in Era 2 (48% versus 34%, P < 0.01 as was the combined outcome of Death after Day 7 or CLD (57% versus 42%, P < 0.01. Multiple regression analysis showed Era 2 birth was a predictor of CLD. However, Poisson regression analysis determined the predictors of all seven major Vermont Oxford Network morbidities were earlier gestational age, lower birth weight, and male gender, not the era of birth. Significantly more infants were discharged home with PDAs in Era 2.Conclusion: Permissive tolerance of PDAs may increase the risk of CLD and Death after Day 7 or CLD but is not associated with significant changes in other Vermont Oxford Network morbidities.Keywords: premature infant

  9. Development of laser Raman and x-ray photoelectron spectroscopic parameters as an additional thermal maturity indicator to the conodont alteration index

    International Nuclear Information System (INIS)

    Marshall, C.P.; Wilson, M.A.


    Full text: Laser Raman spectroscopy and X-ray photoelectron spectroscopy (XPS) was applied in an attempt to quantify and elucidate the chemical transformations of the conodont alteration index (CAI) in artificially matured conodonts. Coniform elements of the genus Drepanodus from the Ordovician Emanuel Formation and pectiniform elements of the genus Polygnathus from the Devonian Napier Formation, both from the Canning Basin were used in this investigation. Samples where specifically chosen to study the effects of genus, element morphology, geological age, lithology and depositional environment upon the CAI. The first order Raman spectra (900-1800 cm-1) of both sets of conodonts show three bands. These are assigned to apatite at 965 cm-1, D band (defects present in the structural units and disorder) at 1345 cm-1 and the G band (carbon-carbon in plane stretching vibration or structural ordered carbon) at 1600 cm-1. The Raman spectra recorded for both sample sets, CAI range of 1-7 are characteristic of poorly/ highly disordered carbon within the conodont organic matter. Further more, the D band becomes progressively narrower and more intense the higher the thermal treatment. The G band becomes narrower until CAI 4 and after that has no systematic change apart from the intensity decreasing with temperature. The most noteworthy spectral characteristic in relation to thermal maturity is the clearly defined linear trend of decreasing D band line-width with increasing rank. The carbon 1s photoelectron regions acquired from both sample sets contain three peaks. These peaks are assigned to carbon bonded to sp3 and sp2 hybridized carbon (284.7 eV), alcohol (287.2 eV) and carboxyl (288.3 eV) functional groups. With increasing thermal treatment all the carbon constituents show a linear decrease in abundance. The poorly/ highly disordered carbon shows no progressive ordering with increasing thermal treatment. This is also in agreement with the XPS results, in which the aliphatic

  10. Best convective parameterization scheme within RegCM4 to downscale CMIP5 multi-model data for the CORDEX-MENA/Arab domain (United States)

    Almazroui, Mansour; Islam, Md. Nazrul; Al-Khalaf, A. K.; Saeed, Fahad


    A suitable convective parameterization scheme within Regional Climate Model version 4.3.4 (RegCM4) developed by the Abdus Salam International Centre for Theoretical Physics, Trieste, Italy, is investigated through 12 sensitivity runs for the period 2000-2010. RegCM4 is driven with European Centre for Medium-Range Weather Forecasts (ECMWF) ERA-Interim 6-hourly boundary condition fields for the CORDEX-MENA/Arab domain. Besides ERA-Interim lateral boundary conditions data, the Climatic Research Unit (CRU) data is also used to assess the performance of RegCM4. Different statistical measures are taken into consideration in assessing model performance for 11 sub-domains throughout the analysis domain, out of which 7 (4) sub-domains give drier (wetter) conditions for the area of interest. There is no common best option for the simulation of both rainfall and temperature (with lowest bias); however, one option each for temperature and rainfall has been found to be superior among the 12 options investigated in this study. These best options for the two variables vary from region to region as well. Overall, RegCM4 simulates large pressure and water vapor values along with lower wind speeds compared to the driving fields, which are the key sources of bias in simulating rainfall and temperature. Based on the climatic characteristics of most of the Arab countries located within the study domain, the drier sub-domains are given priority in the selection of a suitable convective scheme, albeit with a compromise for both rainfall and temperature simulations. The most suitable option Grell over Land and Emanuel over Ocean in wet (GLEO wet) delivers a rainfall wet bias of 2.96 % and a temperature cold bias of 0.26 °C, compared to CRU data. An ensemble derived from all 12 runs provides unsatisfactory results for rainfall (28.92 %) and temperature (-0.54 °C) bias in the drier region because some options highly overestimate rainfall (reaching up to 200 %) and underestimate

  11. Scaled unscented transform Gaussian sum filter: Theory and application

    KAUST Repository

    Luo, Xiaodong


    Lorenz and Emanuel (1998) [27]. We will present the details of implementing the SUT-GSF and examine the effects of filter parameters on the performance of the SUT-GSF. © 2010 Elsevier B.V. All rights reserved.

  12. Importance of ensembles in projecting regional climate trends (United States)

    Arritt, Raymond; Daniel, Ariele; Groisman, Pavel


    We have performed an ensemble of simulations using RegCM4 to examine the ability to reproduce observed trends in precipitation intensity and to project future changes through the 21st century for the central United States. We created a matrix of simulations over the CORDEX North America domain for 1950-2099 by driving the regional model with two different global models (HadGEM2-ES and GFDL-ESM2M, both for RCP8.5), by performing simulations at both 50 km and 25 km grid spacing, and by using three different convective parameterizations. The result is a set of 12 simulations (two GCMs by two resolutions by three convective parameterizations) that can be used to systematically evaluate the influence of simulation design on predicted precipitation. The two global models were selected to bracket the range of climate sensitivity in the CMIP5 models: HadGEM2-ES has the highest ECS of the CMIP5 models, while GFDL-ESM2M has one of the lowestt. Our evaluation metrics differ from many other RCM studies in that we focus on the skill of the models in reproducing past trends rather than the mean climate state. Trends in frequency of extreme precipitation (defined as amounts exceeding 76.2 mm/day) for most simulations are similar to the observed trend but with notable variations depending on RegCM4 configuration and on the driving GCM. There are complex interactions among resolution, choice of convective parameterization, and the driving GCM that carry over into the future climate projections. We also note that biases in the current climate do not correspond to biases in trends. As an example of these points the Emanuel scheme is consistently "wet" (positive bias in precipitation) yet it produced the smallest precipitation increase of the three convective parameterizations when used in simulations driven by HadGEM2-ES. However, it produced the largest increase when driven by GFDL-ESM2M. These findings reiterate that ensembles using multiple RCM configurations and driving GCMs are

  13. PREFACE: Continuum Models and Discrete Systems Symposia (CMDS-12) (United States)

    Chakrabarti, Bikas K.


    Bardhan, Davide Bigoni, Andrej Cherkaev, Hikaru Kawamura, Subhasish Mazumder, Srutarshi Pradhan, Jacques Prost, Sriram Ramaswamy, Ping Sheng, Asok K Sen) were unable to contribute to this proceedings volume; on the other hand, although Kamal could not participate in the symposium, he contributed to the proceedings volume. We are grateful to Lucilla de Arcangelis, Kamal K Bardhan, Abhik Basu, Jayanta K Bhattacharjee, Andrej Cherkaev, Yilong Han, Alex Hansen, Takahiro Hatano, Esin Inan, Hikaru Kawamura, Pradeep K Mohanty, Akio Nakahara, Surajit Sengupta, Ping Sheng, Sujata Tarafdar and Uwe Tauber for reviewing the papers submitted to this proceedings volume. We would like to take this opportunity to thank all the members of the organizing committee and acknowledge the financial support received from the Centre for Applied Mathematics and Computational Science, Saha Institute of Nuclear Physics, Kolkata. We look forward to meeting you all at the next event in this series, CMDS 13, to be held in 2014/2015 in Utah, USA. Bikas K ChakrabartiChairman of CMDS 12Kolkata, 8 August 2011 Editors of the proceedings Abhik Basu K Chakrabarti Kumar Chandra Institute of Nuclear Physics, Sector-I, Block - AF, Bidhannagar, Kolkata 700064, India

  14. Laboratory modeling of air-sea interaction under severe wind conditions (United States)

    Troitskaya, Yuliya; Vasiliy, Kazakov; Nicolay, Bogatov; Olga, Ermakova; Mikhail, Salin; Daniil, Sergeev; Maxim, Vdovin


    Wind-wave interaction at extreme wind speed is of special interest now in connection with the problem of explanation of the sea surface drag saturation at the wind speed exceeding 30 m/s. The idea on saturation (and even reduction) of the coefficient of aerodynamic resistance of the sea surface at hurricane wind speed was first suggested by Emanuel (1995) on the basis of theoretical analysis of sensitivity of maximum wind speed in a hurricane to the ratio of the enthalpy and momentum exchange coefficients. Both field (Powell, Vickery, Reinhold, 2003, French et al, 2007, Black, et al, 2007) and laboratory (Donelan et al, 2004) experiments confirmed that at hurricane wind speed the sea surface drag coefficient is significantly reduced in comparison with the parameterization obtained at moderate to strong wind conditions. Two groups of possible theoretical mechanisms for explanation of the effect of the sea surface drag reduction can be specified. In the first group of models developed by Kudryavtsev & Makin (2007) and Kukulka,Hara Belcher (2007), the sea surface drag reduction is explained by peculiarities of the air flow over breaking waves. Another approach more appropriate for the conditions of developed sea exploits the effect of sea drops and sprays on the wind-wave momentum exchange (Andreas, 2004; Makin, 2005; Kudryavtsev, 2006). The main objective of this work is investigation of factors determining momentum exchange under high wind speeds basing on the laboratory experiment in a well controlled environment. The experiments were carried out in the Thermo-Stratified WInd-WAve Tank (TSWIWAT) of the Institute of Applied Physics. The parameters of the facility are as follows: airflow 0 - 25 m/s (equivalent 10-m neutral wind speed U10 up to 60 m/s), dimensions 10m x 0.4m x 0.7 m, temperature stratification of the water layer. Simultaneous measurements of the airflow velocity profiles and wind waves were carried out in the wide range of wind velocities. Airflow

  15. On the assessment of adverse consequences of Chernobyl accident

    International Nuclear Information System (INIS)

    Burlakova, E.B.


    Complete text of publication follows. Since 1987 till the present time, at the Emanuel Institute of Biochemical Physics, Russian Academy of Sciences, studies on the effect of low-dose low-level irradiation on biophysical and biochemical parameters of the genetic and membrane apparatus of cells of organs of exposed animals are being carried out. We investigated the structural parameters of the genome (by the method of DNA binding to nitrocellulose filters), structural parameters of nuclear, microsomal, mitochondrial, and plasmic (synaptic and erythrocyte) membranes (by the method of spin probes localized in various layers of membranes), the composition and oxidation degree of membrane lipids, and the functional activity of cells - the activity of enzymes, relationship between isozymic forms, and regulating properties. We investigated also the effect of low-level irradiation on the sensitivity of cells, biopolymers, and animals to subsequent action of various damaging factors, including high-dose irradiation. The animals were exposed to a source of 137 Cs γ-radiation at the dose-rates 41.6 x 10 -3 , 4.16 x 10 -3 , and 0.416 x 10 -3 mGy. The doses were varied from 6 x 10 -4 to 1.2 Gy. As a result of the studies performed, the following conclusions were made: 1. Low radiation doses affect actively the metabolism of animals and man. 2. Over certain dose ranges, low-level irradiation is even more effective than acute high-level. 3. The dose-effect dependence of irradiation may be nonlinear, nonmonotonic, and polymodal in character. 4. Doses that cause the extreme effects depend on the irradiation dose-rate (intensity); they are lower at a lower intensity. 5. Low-dose irradiation causes changes (mainly, enhancement) in the sensitivity to the action of other damaging factors. We explain the nonlinear and nonmonotonic dose-effect dependence that we obtained in our experiments with low-dose low-level irradiation by changes in the relationship between damages and reparation

  16. Investigation of orography impact on extreme dry spells over Greece (United States)

    Oikonomou, C.; Flocas, H.; Manola, I.; Hatzaki, M.; Asimakopoulos, D. N.


    Precipitation regime over Greece is controlled by the atmospheric circulation, orography sea surface temperature distribution and land/sea interaction. Previous studies have shown that the precipitation amounts are increased in Western Greece, which is located in the upstream side of the largest mountain range of the central mainland. Furthermore, the longest dry spells were identified in south eastern part of Greece during summer and in northern Greek area during winter. The objective of this study is to investigate the impact of topography on prolonged dry periods over Greece, using the third generation hydrostatic Regional Climate Model RegCM3, which shows a noticeable improvement in the representation of the surface hydrological cycle in mountainous regions. More specifically, an attempt is made to study the distribution of prolonged dry spells during two seasons, summer of 1993 and winter of 1989, over the Greek area, under two different simulation scenarios: the first employs the real orography of the Greek area while in the second one the orography is eliminated, by transforming the models terrain code. Both simulation experiments were conducted with the high spatial resolution of 10 Km, while the MIT-Emanuel Convective Precipitation Scheme was selected for the computation of convective precipitation, as it offers more physical representation of convection compared to the other oldest schemes of RegCM. The model was firstly validated through comparisons of the model outputs with observed precipitation amount data, employing 20 stations over Greece for the two selected seasons. The validation demonstrated that the model can simulate precipitation amount quite well over the Greek area, except for the south Dodecanese Islands, where precipitation is underestimated, and the eastern continental Greece, where the daily precipitation is overestimated. For the identification of the extreme dry spells, the climatic index CDD (Maximum number of consecutive dry days

  17. Rebound macular edema following oral acetazolamide therapy for juvenile X-linked retinoschisis in an Italian family

    Directory of Open Access Journals (Sweden)

    Galantuomo MS


    Full Text Available Maria Silvana Galantuomo,1,* Maurizio Fossarello,1 Alberto Cuccu,1 Roberta Farci,1 Markus N Preising,2 Birgit Lorenz,2 Pietro Emanuele Napoli1,* 1Department of Surgical Sciences, Eye Clinic, University of Cagliari, Cagliari, Italy; 2Department of Ophthalmology, Faculty of Medicine, Justus-Liebig-University, Giessen, Germany *These authors contributed equally to this work Background: Juvenile X-linked retinoschisis (RS1, OMIM: 312700 is a hereditary vitreoretinal dystrophy characterized by bilateral foveal schisis and, in half of the patients, splitting through the nerve fiber layer in the peripheral retina. In the first decade of life, patients usually develop a decrease in visual acuity. Long-term visual outcomes can be poor due to the limited number of known successful treatments. Purpose: The purposes of this study were to present, for the first time, a p.Arg197Cys missense mutation in the RS1 gene (OMIM: 300839 in a four-generation Italian family with RS1 and to examine the clinical response to the treatment with acetazolamide tablets alone or in combination with dorzolamide eye drops as assessed by spectral-domain optical coherence tomography (SD-OCT. Methods: Eleven individuals, including two brothers with RS1 (patients 1 and 2, underwent a full medical history examination and a comprehensive ocular assessment that involved SD-OCT, fluorescein angiography, electroretinography and DNA analysis. Each RS1 patient received oral acetazolamide (375 mg daily during the first three months. Thereafter, patient 1 continued only with dorzolamide eyedrops three times a day for a period of three months, while patient 2 spontaneously stopped both medications. Results: Sequence analysis of the RS1 gene identified a hemizygous c.589C>T (p.Arg197Cys missense mutation in exon 6, which has not been previously reported in an Italian family. A different response to the medical therapy was observed in the four eyes of the two affected brothers hemizygous for

  18. An innovative intervention for the treatment of cognitive impairment–Emisymmetric bilateral stimulation improves cognitive functions in Alzheimer’s disease and mild cognitive impairment: an open-label study

    Directory of Open Access Journals (Sweden)

    Guerriero F


    Full Text Available Fabio Guerriero,1–3 Emanuele Botarelli,3 Gianni Mele,3 Lorenzo Polo,3 Daniele Zoncu,3 Paolo Renati,3,4 Carmelo Sgarlata,1 Marco Rollone,2 Giovanni Ricevuti,1,2 Niccolo Maurizi,1 Matthew Francis,1 Mariangela Rondanelli,5 Simone Perna,5 Davide Guido,2,6 Piero Mannu3 1Department of Internal Medicine and Medical Therapy, Section of Geriatrics, University of Pavia, Pavia, Italy; 2Agency for Elderly People Services, Santa Margherita Hospital, Pavia, Italy; 3Ambra Elektron, Italian Association of Biophysics for the Study of Electromagnetic Fields in Medicine, 4Alberto Sorti Research Institute, Medicine and Metamolecular Biology, Turin, Italy; 5Department of Public Health, Experimental and Forensic Medicine, Section of Human Nutrition, Endocrinology and Nutrition Unit, 6Department of Public Health, Experimental and Forensic Medicine, Biostatistics and Clinical Epidemiology Unit, University of Pavia, Pavia, Italy Background and aims: In the last decade, the development of different methods of brain stimulation by electromagnetic fields (EMF provides a promising therapeutic tool for subjects with impaired cognitive functions. Emisymmetric bilateral stimulation (EBS is a novel and innovative EMF brain stimulation, whose working principle is to introduce very weak noise-like stimuli through EMF to trigger self-arrangements in the cortex of treated subjects, thereby improving cognitive faculties. The aim of this pilot study was to investigate in patients with cognitive impairment the effectiveness of EBS treatment with respect to global cognitive function, episodic memory, and executive functions. Methods: Fourteen patients with cognitive decline (six with mild cognitive impairment and eight with Alzheimer’s disease underwent three EBS applications per week to both the cerebral cortex and auricular-specific sites for a total of 5 weeks. At baseline, after 2 weeks and 5 weeks, a neuropsychological assessment was performed through mini–mental state

  19. Has Anthropogenic Forcing Caused a Discernible Change in Atlantic Hurricane Activity? (United States)

    Knutson, T. R.; Vecchi, G. A.


    There is currently evidence both for and against the existence of a discernible anthropogenic impact on Atlantic hurricane activity. Emanuel's (pers. comm. 2007) Power Dissipation Index shows unprecedented high values in recent decades in the context of the past 60 yr, and correlates remarkably well with low-frequency tropical Atlantic SST variations. The limited record length, partial basin coverage by aircraft in the pre-satellite era, and lack of reconciliation with models limit the usefulness of this result for identifying possible anthropogenic influences. Landsea (EOS, 2007) uses landfalling storm statistics to infer no significant increase in basin-wide tropical storm counts since 1900. Landsea's critical assumption of a constant landfalling fraction over time limits confidence in this assessment. Nonetheless, an important finding is that U.S. landfalling hurricane activity (frequency and PDI) show no increasing trend over the past century or so. Holland and Webster (Phil. Trans. R. Soc. A 2007) conclude that basin-wide tropical cyclone and hurricane counts have increased dramatically during the past century, related to the rise in tropical Atlantic SSTs. Their key assumption is that the existing HURDAT data reliably portrays basin-wide statistics for tropical storms, hurricanes and major hurricanes, at least back to ~1900, which requires further substantiation. We use historical Atlantic ship track and storm track data to estimate the expected number of missing tropical storms each year in the pre-satellite era (1878-1965). After adjustment, the storm counts covary with tropical SSTs on multi-decadal time scales, but their long-term trend (1878-2006) is weaker than the trend in similarly normalized SSTs (though both are nominally positive). The linear trend in adjusted storm counts for 1900-2006 is strongly positive (+4.2 storms/century) and highly significant even after accounting for serial correlation. However, this trend begins near a local minimum in

  20. PREFACE: 17th International Conference on Recent Progress in Many-Body Theories (MBT17) (United States)

    Reinholz, Heidi; Boronat, Jordi


    imaginative use and development of the Monte-Carlo approach and for his ground-breaking contributions to superconductivity. The Kümmel Award went to Max Metlitski (UC Santa Barbara) for remarkable advances in the theory of quantum criticality in metals. The nominations for the Kümmel Award were of such high standard that the Committee announced Honourable Mentions to Martin Eckstein (MPDS/U Hamburg, Germany) for his leading contributions in the development of non-equilibrium dynamical mean field theory, Emanuel Gull (U Michigan, USA) for the development of the Continuous-Time Auxiliary-Field Quantum Monte Carlo Method and for its use in understanding the interplay of the pseudogap and superconductivity in the Hubbard model and Kai Sun (U Michigan, USA) for seminal contributions to the theory of topological effects in strongly correlated electron systems. The Conference continues the series of conferences held before in Trieste, Italy (1979); Oaxtapec, Mexico (1981); Odenthal-Altenberg, Germany (1983); San Francisco, USA (1985); Oulu, Finland (1987); Arad, Israel (1989); Minneapolis, USA (1991); Schloé Segau, Austria (1994); Sydney, Australia (1997); Seattle, USA (1999); Manchester, UK (2001); Santa Fe, USA (2004); Buenos Aires, Argentina (2005); Barcelona, Spain (2007); Columbus, USA (2009) and Bariloche, Argentina (2011). It has been a great pleasure to prepare for the conference. We thank the IAC and in particular Susana Hernandez and David Neilson as well as the International Programme Committee for their great support and advice. Many more people have been involved locally in organizing this international meeting and thanks goes to them, in particular to the members of the LOC Sonja Lorenzen, Dieter Bauer, Niels-Uwe Bastian, Marina Hertzfeldt, Volker Mosert and Gerd Röpke. The next meeting will take place in Buffalo, USA in 2015 and we look forward to yet another exciting exchange on Recent Progress in Many-Body Theories. Heidi Reinholz and Jordi Boronat Guest editors

  1. Segnalazioni/Informes/Rapports/Reports

    Directory of Open Access Journals (Sweden)

    Emanuele Monegato


    Full Text Available di Elisa Cairati, Paolo Caponi, Emanuele Monegato, Anna Pasolini   Amy Stewart, Wicked Plants, London, Timber Press, 2010, 236 pp. ISBN 978-160-469-127-6 Andrea Corrado e Igor Mariottini, Cinema e autori sulle tracce delle migrazioni, Roma, Ediesse, 2013, 155 pp. ISBN 978-882-301-625-5 Carlos Busqued, Sotto questo sole tremendo, Roma, Atmosphere libri, 2012, 141 pp. ISBN 978-88-6564-032-6 Doménico Chiappe, Tan real como la ficción (Herramientas narrativas en periodismo, Barcelona, Editorial Laertes, 2010, 197 pp. ISBN 978-84-7584-704-7 Eduardo Huarag Álvarez, La cultura oral en la narrativa hispanoamericana, Lima, Editorial San Marcos, 2011, 293 pp. ISBN 978-612-302-537-3 Eduardo L. Holmberg, Le ossa, Salerno, Edizioni Arcoiris, 2012, 114 pp. ISBN 978-88-96583-28-9 Guido Bonsaver, Mussolini censore. Storie di letteratura, dissenso e ipocrisia, Bari, Laterza, 2013, 230 pp. ISBN 9788858106624 Leila Guerriero, Frutos extraños (crónicas reunidas 2001-2008, Madrid, Alfaguara, 2009, 400 pp. ISBN 978-84-204-0371-7 Marco Di Domenico, Italiani Pericolosi, Torino, Bollati Boringhieri, 2012, 254 pp. ISBN 978-883-392-335-2 Margo Lanagan, Tender Morsels, New York, Alfred A. Knopf, 2008, 464 pp. ISBN 978-0-375-84305-1 María Caballero Wangüemert, Las trampas de la emancipación. Literatura femenina y mundo hispánico, Madrid, Biblioteca Nueva/Minerva, 2012, 363 pp. ISBN 978-84-9940-529-2 Maria Cristina Paganoni, Representing the City. Linguistic Perspectives,Discursive Strategies and Multimodality in City Branding, Bergamo, Lubrina Editore, 2012, 148 pp. ISBN 978 88 7766 464 8 Michael Denning, Cover Stories. Narrative and Ideology in the British Spy Thriller, London, Routledge, 1987, 168 pp. ISBN 0-7100-9642-9; John G. Cawelti, Bruce A. Rosenberg, The Spy Story, Chicago and London, The University of Chicago Press, 1987, 270 pp. ISBN 0-226- 09868-0 Nicoletta Vallorani, Millennium London. Of Other Spaces and the Metropolis, Milano/Udine, Mimesis, 2012

  2. Surgical pathology in the 20th century at the Mount Sinai Hospital, New York. (United States)

    Geller, Stephen A


    How did the education of surgical pathology, and pathology in general, differ at Mount Sinai? Passing the examination of the American Board of Pathology was never the focus of the department. Learning criteria or quoting references was de-emphasized, but mastery of macroscopic pathology was required, supported in both word and action by two brilliant surgical pathologists, Otani and Kaneko, and by two extraordinary medical pathologists, Klemperer and Popper. Meticulous microscopy emphasized pattern rather than reliance on lists of discrete features. Otani developed a regular "problem case" meeting for a community of pathologists, made up of alumni and other interested pathologists, as well as active department members. These monthly sessions provided the highest level of "continuing medical education." Otani and Kaneko unequivocally believed in learning from cases, and Mount Sinai residents were fortunate both in the one-to-one teaching and in the wealth of material, in all systems, that came to surgical pathology. Outstanding pathologists who came from Mount Sinai settled throughout the country and provided the highest level of diagnoses, but, with the exception of Bernard Wagner, Emanuel Rubin, Fiorenzo Paronetto, Richard Horowitz, Michael Gerber, Marc Rosenblum, Bruce Wenig, Jaishree Jagirdar, Swan Thung, Cesar Moran, Hideko Kamino, Philip LeBoit, Alberto Marchevsky, and others, there were relatively few academic leaders. Otani and Kaneko did not have national reputations. Klemperer, although world renowned, was relatively unassuming, and his disciples numbered almost as many nonpathologists as pathologists. Popper did establish a major center for liver pathology, with students coming from around the world, but did not particularly promote general surgical pathology. Can the Mount Sinai approach still be applied? The decline in the numbers of autopsies performed, the demands for rapid turnaround time, the de-emphasis of gross pathology as newer technologies (eg

  3. Bag-breakup control of surface drag in hurricanes (United States)

    Troitskaya, Yuliya; Zilitinkevich, Sergej; Kandaurov, Alexander; Ermakova, Olga; Kozlov, Dmitry; Sergeev, Daniil


    Air-sea interaction at extreme winds is of special interest now in connection with the problem of the sea surface drag reduction at the wind speed exceeding 30-35 m/s. This phenomenon predicted by Emanuel (1995) and confirmed by a number of field (e.g., Powell, et al, 2003) and laboratory (Donelan et al, 2004) experiments still waits its physical explanation. Several papers attributed the drag reduction to spume droplets - spray turning off the crests of breaking waves (e.g., Kudryavtsev, Makin, 2011, Bao, et al, 2011). The fluxes associated with the spray are determined by the rate of droplet production at the surface quantified by the sea spray generation function (SSGF), defined as the number of spray particles of radius r produced from the unit area of water surface in unit time. However, the mechanism of spume droplets' formation is unknown and empirical estimates of SSGF varied over six orders of magnitude; therefore, the production rate of large sea spray droplets is not adequately described and there are significant uncertainties in estimations of exchange processes in hurricanes. Herewith, it is unknown what is air-sea interface and how water is fragmented to spray at hurricane wind. Using high-speed video, we observed mechanisms of production of spume droplets at strong winds by high-speed video filming, investigated statistics and compared their efficiency. Experiments showed, that the generation of the spume droplets near the wave crest is caused by the following events: bursting of submerged bubbles, generation and breakup of "projections" and "bag breakup". Statistical analysis of results of these experiments showed that the main mechanism of spray-generation is attributed to "bag-breakup mechanism", namely, inflating and consequent blowing of short-lived, sail-like pieces of the water-surface film. Using high-speed video, we show that at hurricane winds the main mechanism of spray production is attributed to "bag-breakup", namely, inflating and

  4. Overexpression of human SOD1 improves survival of mice susceptible to endotoxic shock

    Directory of Open Access Journals (Sweden)

    Charchaflieh J


    Full Text Available Jean Charchaflieh,1,2 Georges I Labaze,1 Pulsar Li,1 Holly Van Remmen,3 Haekyung Lee,1 Helen Stutz,1 Arlan Richardson,3 Asher Emanuel,1 Ming Zhang1,41Department of Anesthesiology, State University of New York (SUNY Downstate Medical Center, New York, NY, USA; 2Department of Anesthesiology, Yale University School of Medicine, New Haven, CT, USA; 3Barshop Center for Longevity and Aging Studies, University of Texas Health Science Center at San Antonio, San Antonio, TX, USA; 4Department of Cell Biology, State University of New York (SUNY Downstate Medical Center, New York, NY, USABackground: Protective effects of the antioxidant enzyme Cu-Zn superoxide dismutase (SOD1 against endotoxic shock have not been demonstrated in animal models. We used a murine model to investigate whether overexpression of SOD1 protects against endotoxic shock, and whether the genetic background of SOD1 affects its effective protective effects and susceptibility to endotoxic shock.Methods: Transgenic (tg mice overexpressing human SOD1 and control mice were divided into four groups based on their genetic background: (1 tg mice with mixed genetic background (tg-JAX; (2 wild-type (WT littermates of tg-JAX strain (WT-JAX; (3 tg mice with C57BL/6J background (tg-TX; (4 WT littermates of tg-TX strain (WT-TX. Activity of SOD1 in the intestine, heart, and liver of tg and control mice was confirmed using a polyacrylamide activity gel. Endotoxic shock was induced by intraperitoneal injection of lipopolysaccharide. Survival rates over 120 hours (mean, 95% confidence interval were analyzed using Kaplan–Meier survival curves.Results: Human SOD1 enzymatic activities were significantly higher in the intestine, heart, and liver of both tg strains (tg-JAX and tg-TX compared with their WT littermates (WT-JAX and WT-TX, respectively. Interestingly, the endogenous SOD1 activities in tg-JAX mice were decreased compared with their WT littermates (WT-JAX, but such aberrant changes were not

  5. Cosmic "Dig" Reveals Vestiges of the Milky Way's Building Blocks (United States)


    Peering through the thick dust clouds of our galaxy's "bulge" (the myriads of stars surrounding its centre), and revealing an amazing amount of detail, a team of astronomers has unveiled an unusual mix of stars in the stellar grouping known as Terzan 5. Never observed anywhere in the bulge before, this peculiar "cocktail" of stars suggests that Terzan 5 is in fact one of the bulge's primordial building blocks, most likely the relic of a proto-galaxy that merged with the Milky Way during its very early days. "The history of the Milky Way is encoded in its oldest fragments, globular clusters and other systems of stars that have witnessed the entire evolution of our galaxy," says Francesco Ferraro from the University of Bologna, lead author of a paper appearing in this week's issue of the journal Nature. "Our study opens a new window on yet another piece of our galactic past." Like archaeologists, who dig through the dust piling up on top of the remains of past civilisations and unearth crucial pieces of the history of mankind, astronomers have been gazing through the thick layers of interstellar dust obscuring the bulge of the Milky Way and have unveiled an extraordinary cosmic relic. The target of the study is the star cluster Terzan 5. The new observations show that this object, unlike all but a few exceptional globular clusters, does not harbour stars which are all born at the same time - what astronomers call a "single population" of stars. Instead, the multitude of glowing stars in Terzan 5 formed in at least two different epochs, the earliest probably some 12 billion years ago and then again 6 billion years ago. "Only one globular cluster with such a complex history of star formation has been observed in the halo of the Milky Way: Omega Centauri," says team member Emanuele Dalessandro. "This is the first time we see this in the bulge." The galactic bulge is the most inaccessible region of our galaxy for astronomical observations: only infrared light can

  6. Utilization of tracheostomy in craniomaxillofacial trauma at a level-1 trauma center. (United States)

    Holmgren, Eric P; Bagheri, Shahrokh; Bell, R Bryan; Bobek, Sam; Dierks, Eric J


    The decision to perform a tracheostomy on patients with maxillofacial trauma is complex. There is little data exploring the role of tracheostomy in facial fracture management. We sought to profile the utilization of tracheostomy in the context of maxillofacial trauma at our institution by comparing patients who required tracheostomy with and without facial fractures versus those with facial fractures not requiring tracheostomy. All patients admitted to the Trauma Service at Legacy Emanuel Hospital and Health Center (LEHHC), Portland, OR, from 1993 to 2003 that sustained facial fractures or underwent tracheostomy were identified and data were retrospectively reviewed using patient charts and the trauma registry. Variables such as age, gender, death, injury severity score (ISS), facial injury severity score (FISS), Glasgow coma score (GCS), intensive care days (ICU), hospital length of stay (LOS), facial fracture profile, and oral and maxillofacial surgery (OMFS) operative intervention were tabulated and analyzed. Data were divided into 3 groups for comparison: group 1 (ffxT) consisted of patients who underwent a tracheostomy procedure and repair of their facial fracture during the SAME operation by the OMFS department (N = 125); group 2 (ffxNT) were those patients who had repair of their facial fractures by OMFS and did not require a tracheostomy (N = 224); and group 3 (NffxT) were patients who did not have facial fractures but received a tracheostomy during their hospitalization (N = 259). Ten-year data were used to analyze the ffxT and 5-year data were used to analyze the ffxNT and NffxT. Analysis of variance and chi2 testing was used for statistical analysis. A total of 18,187 patients were admitted to the trauma LEHHC Trauma Service during the study period, of which 1,079 (5.9%) patients sustained facial fractures and 788 (4.3%) required a tracheostomy. One hundred twenty-five patients (0.69% of total; 11.6% of facial fracture) received a tracheostomy at the

  7. PREFACE: XXVIth International Conference on Photonic, Electronic and Atomic Collisions (United States)

    Orel, Ann; Starace, Anthony F.; Nikolić, Dragan; Berrah, Nora; Gorczyca, Thomas W.; Kamber, Emanuel Y.; Tanis, John A.


    developing/disadvantaged countries. All in all, the XXVIth ICPEAC in Kalamazoo was very successful. The plenary lectures and the progress and special reports bridged the gap between the different fields of collision physics, making it possible for non-experts in a given area to gain insight into new areas. Also, included among the speakers were several young scientists, namely, postdocs and students, who brought new perspectives to their fields. The next ICPEAC will take place in Belfast in 2011, and the ones after that will be in Lanzhou in 2013 and Madrid in 2015. Given the rapidity with which science is advancing in all of the areas covered by ICPEAC, we expect that these future ICPEAC conferences will be as stimulating as this most recent one was, as indicated by the contributions presented in this proceedings volume. Ann Orel, University of California-Davis Anthony F Starace, University of Nebraska-Lincoln Dragan Nikolić, Western Michigan University Nora Berrah, Western Michigan University Thomas W Gorczyca, Western Michigan University Emanuel Y Kamber, Western Michigan University John A Tanis, Western Michigan University The PDF file contains details of the Sponsors and Exhibitors, Committees and Previous Proceedings. Conference photograph

  8. The effect of foam on waves and the aerodynamic roughness of the water surface at high winds (United States)

    Troitskaya, Yuliya; Vdovin, Maxim; Sergeev, Daniil; Kandaurov, Alexander


    the waved water surface. For the case of water surface covered with foam, good agreement was obtained between the predictions of the model with the roughness parameter correlated with the size of the foam bubbles and the experimental data. This confirms the non-separated character of the air flow around waves in the case of enhanced surface roughness. It was shown that the presence of foam reduces the heights and mean square slopes of waves for all wind speeds. At wind speeds below 20-22 m / s foam presence increases the drag coefficient, while at wind speeds above 22-25 m / s, drag coefficient slightly decreases in the presence of the foam. The dependence of water surface drag coefficient in the presence of a foam on the wind velocity is determined by the balance between the small-scale surface roughness increase and decrease of wave form-drag compared to the case of water free of foam. This work was supported by the Russian Foundation of Basic Research (16-05-00839, 16-55-52025, 15-35-20953) and experiment and equipment was supported by Russian Science Foundation (Agreements 14-17-00667 and 15-17-20009 respectively), Yu.Troitskaya, A.Kandaurov and D.Sergeev were partially supported by FP7 Collaborative Project No. 612610. References 1. Emanuel, K.A.. / J. Atmos. Sci, Vol.52, No 22, p.3969-3976, 1995 2. Powell, M.D., Vickery P.J., Reinhold T.A.. / Nature , v.422, p.279-283, 2003 3. Donelan M.A., Haus B.K , Reul N., Plant W.J., Stiassnie M., Graber H. C., Brown O. B., Saltzman E. S. /. Geophys. Res. Lett., , v.31, L18306. 2004 4. Kudryavtsev V., Makin V. / Boundary-Layer Meteorol., v.125, p. 289-303. 2007 5. Kukulka, T., T. Hara, and S. E. Belcher/., Vol 37, No 11, p. 1811-1828, 2007. 6. Makin V. K. / Boundary Layer Meteorol., , Vol. 115, No1, p.169-176. 2005 7. Kudryavtsev V. N. // J. Geophys. Res., 2006, v.111, C07020 (2006) 8. Golbraikh E., Shtemler Y.M. Dynamics of Atmospheres and Oceans 73 (2016) 1-9

  9. Obituary: Clifford G. Toner (1959-2009) (United States)

    Hill, Frank


    in Hawai'i, K.D. Leka, recalls that "Cliff was the embodiment of a "gentle giant"; so tall, yet so soft-spoken and patient, and I just recall a sense of his always being ready to help any living thing. Cliff was out with a back injury in March 1991, and it was under his temporarily-abandoned desk that Betsy, the IfA cat had her one (and only) litter (when my cat Audrey, whom many of you know, was born). As the littermates grew, Cliff, Matt Penn and I had kittens crawling over us; I can still hear his chuckles, "well helloooh, who are you there now?" as they would scramble up his chair to his desk. It was always with a smile that he'd greet me when we ran into each other after the "Hawai'i days"; we'd swap some stories, kid updates but only recently we were more in touch as I'm now playing with GONG data. I was heartened to hear he was working on the magnetogram merging, because I knew it'd be done really well with his attention." Cliff Toner was a caring and loving person, an excellent scientist, and a hero of GONG. He will be sorely missed by everyone who knew him. He is survived by his wife, Nelsey, children, Ariel, Nathaniel, Miranda, and Kayla, sister Gloria, brothers Ethan (Heather) and Emanuel (Lisa).

  10. Reflections About the Role of Intellectuals in Latin America Reflexiones acerca del rol de los intelectuales en América Latina Reflexões sobre o papel dos intelectuais na América Latina

    Directory of Open Access Journals (Sweden)

    Judith Naidorf


    intellectual debate but to contribute to a not new but always applicable, which should be a breakthrough for each of our practices in the different social areas in which we daily work.

    En este trabajo nos proponemos abordar algunos aspectos teórico - conceptuales que contribuyan a la reflexión sobre la especificidad del papel del intelectual latinoamericano actual. Los aportes de diversos autores nos ayudarán a caracterizar un rol que se encuentra en permanente reformulación, análisis y discusión. La propuesta es retomar los desarrollos teóricos de la categoría de intelectual, desde Antonio Gramsci e Immanuel Wallerstein principalmente, pasando por sus momentos más intensos en la década del 60-70 con Sartre y Foucault en Europa. También se rescatan las contribuciones realizadas por Pierre Bourdieu, Sousa Santos y los aportes para América Latina de Fals Borda, Florestán Fernández, Octavio Ianni y Eliseo Verón, entre otros. Además se incluyen como ejemplos declaraciones del subcomandante Marcos para el EZLN y se hace referencia a los análisis realizados por Julio Gambina y Daniel Campione para el caso argentino. No es interés de este trabajo arribar a definiciones acabadas acerca de la función social del intelectual sino aportar a un debate no nuevo pero siempre vigente. Neste trabalho pretendemos abordar alguns aspectos teóricos-conceituais que contribuem para a reflexão sobre especificidade do papel do intelectual latino-americano atual. As contribuições de diferentes autores nos ajudam a caracterizar um papel que está constantemente sendo repensado, a análisado e discutido. A proposta é revisitar aos desenvolvimentos teóricos sobre o "intelectual" de Antonio Gramsci e Emanuel Wallerstein principalmente através dos debates mais intensos na década de 60-70 com Sartre e Foucault na Europa. Também se destacam as contribuições feitas por Pierre Bourdieu, Sousa Santos e contribuições desde América Latina de

  11. Discurso del 24 de julio de 1947 ante la Asamblea Constituyente

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    Benedetto Croce


    Full Text Available El 26 de enero de 1910, a los cuarenta y tres años de edad, Benedetto Croce es nombrado Senador. Inicia así una larga y compleja carrera política marcada por una siempre atenta mirada a los grandes temas de la situación política italiana de la primera mitad del siglo XX, pese a que, tanto por su carácter sobrio y discreto, como por el progresivo arrinconamiento del Parlamento durante el régimen fascista sobre todo a partir de los años treinta, sus actuaciones son relativamente escasas. Estas contadas ocasiones en las que tomó parte activa suponen, siempre y en todo caso, no solo un reflejo de la evolución y desarrollo de sus presupuestos filosóficos, éticos y morales a lo largo de más de cuatro décadas, sino que son al mismo tiempo un claro ejemplo de su compromiso intelectual. Sirvan de ejemplo, en este sentido, algunas de sus intervenciones tal vez menos recordadas, como la del 6 de julio de 1920, año en que fue nombrado Ministro della Pubblica Istruzione con el gobierno de Giolitti, en la que proponía una necesaria reforma de los exámenes estatales con la intención de revigorizar la escuela pública; o el discurso del 24 de mayo de 1929, en el que se oponía a la instrumentalización política por parte de Mussolini del Concordato con la Santa Sede. Tras la caída del régimen Croce volvió a la arena política aceptando la presidencia del Partido Liberal Italiano, buscando la conciliación de los distintos partidos antifascistas durante el periodo de la Resistencia y aceptando en 1944 el cargo de Ministro sin cartera en el segundo gobierno de Badoglio, y ello pese a las graves discrepancias que mantenía tanto con él como con Vittorio Emanuele III, a los que no dudó en echar en cara su connivencia con Mussolini. Pocos meses después, en junio de 1944, y una vez liberada Roma, Croce retoma su actividad política formando parte del segundo gobierno de Bonomi, aunque apenas se mantendrá en el cargo unos pocos meses

  12. Improved data for integrated modeling of global environmental change (United States)

    Lotze-Campen, Hermann


    2011 Impacts of population growth, economic development, and technical change on global food production and consumption Agricult. Syst. 104 204-15 Verburg P H, Ellis E C and Letourneau A 2011 A global assessment of market accessibility and market influence for global environmental change studies Environ. Res. Lett. 6 034019 Woodward F I, Smith T M and Emanuel W R 1995 A global land primary productivity and phytogeography model Glob. Biogeochem. Cycles 9 471-90

  13. Book Reviews

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    C. Salmon


    hukum bagi rakyat di Indonesia, Ph.D thesis Airlangga University, Surabaya: Airlangga University Press, 1985, xviii + 308 pp. - J.M.C. Pragt, Volker Moeller, Javanische bronzen, Staatliche Museen Preussischer Kulturbesitz, Museum für Indische Kunst, Berlin, 1985. Bilderheft 51. 62 pp., ill. - J.J. Ras, Friedrich Seltmann, Die Kalang. Eine Volksgruppe auf Java und ihre Stamm-Myth. Ein beitrag zur kulturgeschichte Javas, Stuttgart: Franz Steiner Verlag Wiesbaden GmbH, 1987, 430 pp. - R. Roolvink, Russell Jones, Hikayat Sultan Ibrahim ibn Adham, Berkeley: Center for South and Southeast Asia Studies, University of California, Monograph Series no. 57, 1985. ix, 332 pp. - R. Roolvink, Russell Jones, Hikayat Sultan Ibrahim, Dordrecht/Cinnaminson: Foris, KITLV, Bibliotheca Indonesica vol. 24, 1983. 75 pp. - Wim Rutgers, Harry Theirlynck, Van Maria tot Rosy: Over Antilliaanse literatuur, Antillen Working Papers 11, Caraïbische Afdeling, Koninklijk Instituut voor Taal-, Land- en Volkenkunde, Leiden, 1986, 107 pp. - C. Salmon, John R. Clammer, ‘Studies in Chinese folk religion in Singapore and Malaysia’, Contributions to Southeast Asian Ethnography no. 2, Singapore, August 1983, 178 pp. - C. Salmon, Ingo Wandelt, Wihara Kencana - Zur chinesischen Heilkunde in Jakarta, unter Mitarbeit bei der Feldforschung und Texttranskription von Hwie-Ing Harsono [The Wihara Kencana and Chinese Therapeutics in Jakarta, with the cooperation of Hwie-Ing Harsono for the fieldwork and text transcriptions], Kölner ethopgraphische Studien Bd. 10, Berlin: Dietrich Reimer Verlag, 1985, 155 pp., 1 plate. - Mathieu Schoffeleers, 100 jaar fraters op de Nederlandse Antillen, Zutphen: De Walburg Pers, 1986, 191 pp. - Mathieu Schoffeleers, Jules de Palm, Kinderen van de fraters, Amsterdam: De Bezige Bij, 1986, 199 pp. - Henk Schulte Nordholt, H. von Saher, Emanuel Rodenburg, of wat er op het eiland Bali geschiedde toen de eerste Nederlanders daar in 1597 voet aan wal zetten. De Walburg Pers

  14. Deep Sky Diving with the ESO New Technology Telescope (United States)


    Padova, Italy), Luiz da Costa (ESO), Eiichi Egami (MPI Extraterrestrial Physics, Garching, Germany), Adriano Fontana (Rome Observatory, Italy), Bernard Fort (Paris Observatory, France), Laurent Gautret (Paris Observatory, France), Emanuele Giallongo (Rome Observatory, Italy), Roberto Gilmozzi, Richard N.Hook and Bruno Leibundgut (ESO), Yannick Mellier and Patrick Petitjean (IAP, Paris, France), Alvio Renzini, Sandra Savaglio and Peter Shaver (ESO), Stella Seitz (Munich Observatory, Germany) and Lin Yan (ESO). [2]. The photometric redshift method allows to determine an approximate distance of a distant galaxy by measuring its colour, i.e., its relative brightness (magnitude) in different wavebands. It is based on the proportionality between the distance of a galaxy and its recession velocity (the Hubble law). The higher the velocity, the more its emission will be shifted towards longer wavelengths and the redder is the colour. Recent investigations of galaxies seen in the Hubble Deep Field have shown that the redshifts (and thus distances) found by this method are quite accurate in most cases. How to obtain ESO Press Information ESO Press Information is made available on the World-Wide Web (URL: ). ESO Press Photos may be reproduced, if credit is given to the European Southern Observatory.

  15. Deepest Infrared View of the Universe (United States)


    presented in this Press Release is based on a research article ("Ultradeep Near-Infrared ISAAC Observations of the Hubble Deep Field South: Observations, Reduction, Multicolor Catalog, and Photometric Redshifts" by Ivo Labbé et al.) that will soon appear in the research journal "Astronomical Journal" (cf. astro-ph/0212236). A shorter account will appear in the December 2002 issue of ESO's house journal "The Messenger". Information, including photos and reduced data, is also available at the website of the FIRES project. Notes [1]: This press release is issued in coordination between ESO, Leiden Observatory, the Netherlands Research School for Research in Astronomy (NOVA) and the Netherlands Foundation for Research (NWO). A Dutch-language version is available here. [2]: The team consists of Ivo Labbé, Marijn Franx, Natascha M. Förster Schreiber, Paul van der Werf, Huub Röttgering, Lottie van Starkenburg, Arjen van de Wel and Konrad Kuijken (Leiden Observatory, The Netherlands), Gregory Rudnick (Max-Planck-Institut für Astrophysik, Garching, Germany), Hans-Walter Rix (Max-Planck-Institut für Astronomie, Heidelberg, Germany), Alan Moorwood and Emanuele Daddi (ESO, Garching, Germany) and Pieter G. van Dokkum (California Institute of Technology, Pasadena, USA). [3]: In astronomy, the redshift denotes the fraction by which the lines in the spectrum of an object are shifted towards longer wavelengths. The observed redshift of a remote galaxy provides an estimate of its distance.

  16. Система безопасности в Балтийском регионе как проекция глобального противостояния России и США=Security in the Baltic region as a Projection of Global Confrontation between Russia and the USA

    Directory of Open Access Journals (Sweden)

    Volovoy Vadim


    Full Text Available This article considers the problem of security in the Baltic region, namely, that of Poland and the Baltics. The authors rely on the works of Karl Deutsch, Emanuel Adler, on Michael Barnett’s theory of security communities and Barry Buzan’s re­gional security complex theory, address Steven Mann’s controlled chaos theory and the concept of Intermarium. Their starting assumption is that the situation in the Baltic depends largely on the politics of external powers — Russia and the United States, — being a projection of their global geopolitical confrontation. The US strategy thus becomes a major part of the equation. The authors believe that since the end of the second Iraq war the American elite has been divided along ideological lines into adherents of the chaos theory and traditionalists thinking in terms of sharing control with the other centres of global power. The US strategy in the Baltic region does not seek an open military conflict with Russia. On the contrary, the US strives to preserve the current level of confrontation between Russia and the EU, convincing the latter of the reality of the Russian threat. Countries that traditionally support confrontation with Russia, Poland and the Bal­tics, serve as a conduit for Washington strategy in Europe and a cordon sanitaire. This function is implemented through the Intermarium project meant to separate Russia from the EU. The four countries are rather active in this area, striving to attain the status of the US principal partners in the region and Europe in general. To retaliate, Moscow does everything within its power to ‘separate’ Brussels from Washington, yet the US influence is still very strong in Europe. [Рассматривается проблематика безо­пасности Балтийского региона, как Поль­ши, так и стран Балтии. В качестве тео­ре­тический основы используются

  17. Rare Disease Patient Registry & Natural History Study - Coordination of Rare Diseases at Sanford (United States)


    Rare Disorders; Undiagnosed Disorders; Disorders of Unknown Prevalence; Cornelia De Lange Syndrome; Prenatal Benign Hypophosphatasia; Perinatal Lethal Hypophosphatasia; Odontohypophosphatasia; Adult Hypophosphatasia; Childhood-onset Hypophosphatasia; Infantile Hypophosphatasia; Hypophosphatasia; Kabuki Syndrome; Bohring-Opitz Syndrome; Narcolepsy Without Cataplexy; Narcolepsy-cataplexy; Hypersomnolence Disorder; Idiopathic Hypersomnia Without Long Sleep Time; Idiopathic Hypersomnia With Long Sleep Time; Idiopathic Hypersomnia; Kleine-Levin Syndrome; Kawasaki Disease; Leiomyosarcoma; Leiomyosarcoma of the Corpus Uteri; Leiomyosarcoma of the Cervix Uteri; Leiomyosarcoma of Small Intestine; Acquired Myasthenia Gravis; Addison Disease; Hyperacusis (Hyperacousis); Juvenile Myasthenia Gravis; Transient Neonatal Myasthenia Gravis; Williams Syndrome; Lyme Disease; Myasthenia Gravis; Marinesco Sjogren Syndrome(Marinesco-Sjogren Syndrome); Isolated Klippel-Feil Syndrome; Frasier Syndrome; Denys-Drash Syndrome; Beckwith-Wiedemann Syndrome; Emanuel Syndrome; Isolated Aniridia; Beckwith-Wiedemann Syndrome Due to Paternal Uniparental Disomy of Chromosome 11; Beckwith-Wiedemann Syndrome Due to Imprinting Defect of 11p15; Beckwith-Wiedemann Syndrome Due to 11p15 Translocation/Inversion; Beckwith-Wiedemann Syndrome Due to 11p15 Microduplication; Beckwith-Wiedemann Syndrome Due to 11p15 Microdeletion; Axenfeld-Rieger Syndrome; Aniridia-intellectual Disability Syndrome; Aniridia - Renal Agenesis - Psychomotor Retardation; Aniridia - Ptosis - Intellectual Disability - Familial Obesity; Aniridia - Cerebellar Ataxia - Intellectual Disability; Aniridia - Absent Patella; Aniridia; Peters Anomaly - Cataract; Peters Anomaly; Potocki-Shaffer Syndrome; Silver-Russell Syndrome Due to Maternal Uniparental Disomy of Chromosome 11; Silver-Russell Syndrome Due to Imprinting Defect of 11p15; Silver-Russell Syndrome Due to 11p15 Microduplication; Syndromic Aniridia; WAGR Syndrome; Wolf

  18. Reviewer Database

    Directory of Open Access Journals (Sweden)

    Chief Editor


    Full Text Available REVIEWER DATABASEA S PaddaAarati KrishnanAarti KapilAbdul JilaniAbhaya JoglekarAbhijit PakhareAbhisek MishraAbhishek ArunAbhishek GuptaAbhishek JadhavAbhishek SinghAditi SinghAdrija RoyAdwitiya MukhopadhyayAhmed MandilA SubramanianAjit SahaiAkanksha GautamAkela MohamedAkhila GopinathanAkshay KumarAlankrata JainAli AbediAlisha SyiemliehAmal BasuAmandeep KaurA ChauhanAmarnath GuptaAmar SinhaAmir M KhanAmit KaushikAmit PawaiyaAmit SinghAmrita KansalAmrita SougaijamA WadheraAnand DixtA NeelakantanAnil PurtyAnimesh JainAnisha MohanAnjali AroraAnjan DattaAnju GahlotAnkita BajpaiAnku SaikiaAnmol GoyalAnu AgrawalAnu BhardwajAnuj JangraAnupama AryaA MohokarAnurag ChaudaryA SrivastavaAr BondArnab GhoshArpan YagnikArpit PrajapatiArshad AyubArti RauthanArun SainiArun SharmaArun ShiraliArun SugumaranArun VargheseArun WanjpeArvind NathArvind SinghAsha RAshish ChauhanAshish SinhaAshish SrivastavaAshish YadavAshok BhardwajAshok SrivastavaAshu GroverAshutosh SarwaAshwani SinhaAshwini KumarAthar AnsariAtul PuthiaAustin OkpanmaAvijit DasAvijit SinghaAvinash SunthliaB P MathurB VermaBabu DilipBadri MisraBaridalyne NongkynrihBhaswati SenguptaBhavana PandeyBhavana PantBhola NathBhupinder AnandBhupinder SinghBhuwan SharmaBiju SomanBimlesh KumarBinod KumarBinod PatroBishwas AcharyaBiswajit PaulB ChakravarthyB MannaC M S RawatC P MishraC M SinghChandra PrabhaChibi RushithaChitrangada MistryD SrivastavaDaksh SharmaDaneshwar SinghDanish ImtiazDebabrata RoyDeep ShikhaDeepa NairDeepak ChopraDeepak GuptaDeepak SharmaDeepika MittalNandanwarD SharmaDevi NairDharma BhattaD GahwaiDheeraj SharmaDhiraj SrivastavaDhrubajyotiDileepanDinesh BhatnagarDipanjan DeyDivya RajaseharanEkta GuptaEmanuel CummingsEnakshi GanguliFabrice JotterandFatma KarasuFomboh RichardGagan GargGajendra GuptaGarima MittalG BandyopadhyayGeetanjali KapoorGeetu SinghGhos AhmedGirish ChavanGirjesh YadavGita NegiGmsubba RaoGnanakshiGobezie TemesgenGokul ShindeGouri PadhyKassa GideboGunjan NathH ChopraHameeda Ali

  19. 5th National Congress of the Italian Society of Physiotherapy

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    Alessandro Aina


    Full Text Available Table of contents S1 Criteria for exercises selection in subjects with low back pain Alessandro Aina S2 Recent advances in pathophysiology and treatment of myofascial trigger points Marco Barbero S3 Rehabilitation of scapular dyskinesia Barbara Cagnie S4 Musculoskeletal rehabilitation in subjects affected by neurological disorders Elena Castelli S5 Which examination tests suggest the best candidates for manual therapy Chad Cook S6 Case study: the role of the measurements for the identification of targets and guidance of the treatment Silvano Ferrari S7 Assessment of joint mobility: state of the art Andrea Foglia, Paolo Bizzarri S8 Core stabilization exercises in the treatment of urinary incontinence Donatella Giraudo S9 Preventing surgical subacromial decompression through rotator cuff rehabilitation Chris Littlewood S10 Methodological aspects of Clinical Prediction Rules in the rehabilitation of Low Back Pain Paolo Pillastrini S11 Interpretability of outcome measures in musculoskeletal rehabilitation Daniele Piscitelli S12 Conservative treatment of the misalignment of the spine: state of the art and perspectives Michele Romano S13 Balance training in subjects with musculoskeletal disorders Andrea Tettamanti S14 Dosage of manual therapy: principles for clinical practice Carla Vanti S15 Are there speed limits in post-surgery lower limb rehabilitation? Stefano Vercelli S16 Classification of predominant neuropathic, nociceptive or central sensation pain Lennard Voogt P1 A wearable proprioceptive stabilizer (Equistasi® for rehabilitation of balance disorders in multiple sclerosis patients: preliminary results of a randomized, double-blind, versus placebo controlled study Aceto Maria, Spina Emanuele, Paone Paolo, Silvestre Francesco, Carotenuto Antonio, Cerillo Ilaria, Orefice Giuseppe P2 Effect of repeated neck retraction movements on strength and EMG activity of the upper limbs, range of motion and cervical posture Bassi Raffaele, Fiorito Serena

  20. List of Participants (United States)


    WyderKatholieke Universiteit Leuven Ahmed YoussefAstroParticule et Cosmologie (APC), Université Paris Diderot Daniela ZanonUniversità Degli Studi di Milano Andrea ZanziPhysikalisches Institut, Universität Bonn Andrey ZayakinInstitute for Theoretical and Experimental Physics (ITEP), Moscow Tobias ZinggUniversity of Iceland Dimitrios ZoakosUniversidade de Santiago de Compostela Emanuele ZorzanUniversità di Milano Konstantinos ZoubosNiels Bohr Institute, København