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Sample records for na metabolyichnij sindrom

  1. Abordagem neurologica na sindrome do X fragil

    OpenAIRE

    Marilisa Mantovani Guerreiro

    1993-01-01

    Resumo: Com o propósito de realizar a abordagem neurológica na Síndrome do X Frágil (SXF), estudaram-se 11 pacientes com este diagnóstico citogenético. A idade variou de 8 a 19 anos. Nove pacientes eram do sexo masculino e dois do feminino. Todos os indivíduos apresentaram pavilhões auriculares grandes e faces alongadas. Observou-se fronte proeminente em 63% dos casos e macrorquidia em 33% dentre aqueles do sexo masculino. Atraso na aquisição da fala, fala repetitiva, perseverativa, impulsiva...

  2. Cistatina C, PCR, Log TG/HDLc e Sindrome Metabolica estao Relacionados a Microalbuminuria na Hipertensao

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    Rafaela do Socorro Souza e Silva Moura

    2014-01-01

    Full Text Available Fundamento: Em pacientes com hipertensão arterial sistêmica, a microalbuminúria é um marcador de lesão endotelial e está associada a um risco aumentado de doença cardiovascular. Objetivo: O objetivo do presente estudo foi determinar os fatores que influenciam a ocorrência de microalbumiúria em pacientes hipertensos com creatinina sérica menor que 1,5 mg/dL. Métodos: Foram incluídos no estudo 133 pacientes brasileiros atendidos em um ambulatório multidisciplinar para hipertensos. Pacientes com creatinina sérica maior do que 1,5 mg/dL e aqueles com diabete mellitus foram excluídos do estudo. A pressão arterial sistólica e diastólica foi aferida. O índice de massa corporal (IMC e a taxa de filtração glomerular estimada pela fórmula CKD-EPI foram calculados. Em um estudo transversal, creatinina, cistatina C, colesterol total, HDL colesterol, LDL colesterol, triglicerídeos, proteína C-reativa (PCR e glicose foram mensurados em amostra de sangue. A microalbuminúria foi determinada na urina colhida em 24 horas. Os hipertensos foram classificados pela presença de um ou mais critérios para síndrome metabólica. Resultados: Em análise de regressão múltipla, os níveis séricos de cistatina C, PCR, o índice aterogênico log TG/HDLc e a presença de três ou mais critérios para síndrome metabólica foram positivamente correlacionados com a microalbuminuria (r2: 0,277; p < 0,05. Conclusão: Cistatina C, PCR, log TG/HDLc e presença de três ou mais critérios para síndrome metabólica, independentemente da creatinina sérica, foram associados com a microalbuminúria, um marcador precoce de lesão renal e de risco cardiovascular em pacientes com hipertensão arterial essencial.

  3. Prevalensi Sindrom Metabolik pada Pekerja Perusahaan

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    Zahtamal Zahtamal

    2014-12-01

    Full Text Available Sindrom metabolik adalah masalah kesehatan yang prevalensinya cenderung meningkat pada pekerja. Penelitian ini bertujuan memaparkan prevalensi kasus sindrom metabolik yang terjadi pada pekerja perusahaan. Penelitian ini dilakukan pada tahun 2014 pada dua perusahaan di Provinsi Riau dengan rancangan potong lintang. Sumber data adalah rekam medis pekerja yang melakukan medical check up periode Oktober 2013 hingga Februari 2014. Populasi adalah pekerja yang menderita sindrom metabolik sebanyak 131 orang. Sampel penelitian dipilih dengan cara total sampling yakni 131 orang. Instrumen adalah kuesioner, international physical activity questionnaire, tabel 24 hours food recall, dan tabel bantu pencatatan komponen sindrom metabolik. Pengelolaan data dilakukan secara kuantitatif menggunakan analisis univariat dan bivariat, dengan uji korelasi Spearman’s Rho dan kai kuadrat. Hasil penelitian mendapatkan prevalensi sindrom metabolik sebanyak 21,58%, dengan jenis kelamin terbanyak adalah laki-laki, kelompok usia terbanyak adalah > 50 tahun. Sebagian besar kasus sindrom metabolik memiliki tiga komponen, dengan komponen terbanyak adalah lingkar perut dan tekanan darah. Sebanyak 23,50% kasus memiliki riwayat keluarga obesitas dan diabetes melitus. Sebagian besar kategori aktivitas adalah sedang. Jenis asupan makanan dengan kategori tidak sesuai dengan diet adalah serat pangan dan lemak jenuh. Variabel lingkar perut berhubungan bermakna secara statistik dengan tekanan darah sistolik dan diastolik serta kadar kolesterol high density lipoprotein (p 50 years. Most cases of metabolic syndrome has three components, with the largest component is the abdominal circumference and blood pressure. A total of 23.50% of cases have a family history of obesity and diabetes mellitus. Most categories of activity is moderate. Most types of food intake in the category “out of dietary guidelines” are dietary fiber and saturated fat. Abdominal circumference variable has a

  4. Perbedaan Sindrom Metabolik Pada Wanita Vegetarian Tipe Vegan Dan Non Vegan

    OpenAIRE

    Setiyani, Diah Ari; Wirawanni, Yekti

    2012-01-01

    Latar Belakang: Sindrom metabolik adalah kumpulan kelainan metabolik yang dikaitkan dengan peningkatan risiko penyakit kardiovaskular. Diet vegetarian terutama vegan dapat berperan dalam penurunan risiko sindrom metabolik, tetapi masih didapatkan penelitian yang menyatakan bahwa vegan berisiko sindrom metabolik bahkan lebih tinggi daripada non vegan. Penelitian ini bertujuan untuk mengetahui perbedaan sindrom metabolik pada wanita vegetarian vegan dan non vegan. Metode: Penelitian ini dilakuk...

  5. ERITEMA NODOSO Y SINDROME FEBRIL PROLONGADO ASOCIADOS A HIPERPARATIROIDISMO SECUNDARIO

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    Enz P

    2005-06-01

    Full Text Available El hiperparatiroidismo secundario es uno de los principales disturbios causados por la insuficiencia renal crónica, y la paratohormona es considerada una de las toxinas del sindrome urémico. El sindrome febril prolongado secundario a hiperparatiroidismo primario ya ha sido descripto en la literatura, aunque no lo ha sido aun el inducido por hiperparatiroidismo secundario. En el presente reporte se presenta un caso de eritema nodoso y sindrome febril prolongado asociado a hiperparatiroidismo secundario y que resolvió luego de efectuada una paratiroidectomía subtotal.

  6. Consequências da síndrome da tensão pré-menstrual na vida da mulher Consequencias de la sindrome de la tension pre-menstrual en la vida de la mujer The consequences of the syndrome of the pre-menstrual tension in the woman's life

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    Clarice H. Muramatsu

    2001-09-01

    Full Text Available Este estudo tem como objetivo identificar as possíveis conseqüências da Síndrome da Tensão Pré-Menstrual na vida da mulher. Através do questionário, identificamos distúrbios relacionados a alterações físicas, emocionais e, como consequências às alterações nos relacionamentos envolvendo filho, marido/ namorado e familiar, assim como no ambiente de trabalho.Este estudio tuvo como objetivo identificar las posibles consequencias de la sindrome de la tensión pre-menstrual en la vida de la mujer. Atraves de un questionário, identificamos disturbios relacionados con alteraciones físicas y emocionales que por vez danãn los relacionamentos envolviendo hijo, marido, enamorado y familiares, asi como en el ambiente de trabajo.This study has as objective to identify the possible consequences of the Syndrome of the Pré-menstrual Tension in the woman's life. Through the questionnaire, we identified disturb related to physical and emotional discomfort and as consequences the alterations in the relationships involving son, husband / boyfriend and family, as well as in the work atmosphere.

  7. Tata Laksana Non Imunosupresan Sindrom Nefrotik pada Anak

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    Sudung Oloan Pardede

    2017-08-01

    Full Text Available Sindrom nefrotik adalah keadaan klinis yang terdiri atas proteinuria masif, hipo­albuminemia (< 2,5 g/dL, edema, dan hiperkolesterolemia. Terapi utama sindrom nefrotik adalah imunosupresan terutama kortikosteroid. Pada sindrom nefrotik relaps sering atau dependen steroid, dan sindrom nefrotik resisten steroid, selain steroid diberikan juga imunosupresan lain seperti siklofosfamid, siklosporin, mikofenolat mofetil, takrolimus, atau pun levamisol. Selain pemberian imunosupresan diperlukan terapi suportif, yang meliputi terapi diitetik,  tata laksana edema, hipertensi, hipovolemia, trombosis, hiperlipidemia, dan infeksi. Tata laksana diitetik terdiri atas kalori yang adekuat, protein sesuai recommended daily allowance, lemak low saturated, dan rendah garam. Komposisi zat gizi yang dianjurkan terdiri atas 10-14% protein; 40-50% lemak poly- dan monounsaturated, 40-50% karbohidrat. Tata laksana  edema terdiri atas restriksi cairan, pemberian diuretik, dan infus albumin jika perlu. Infeksi yang sering terjadi pada sindrom nefrotik adalah selulitis peritonitis, dan pneumonia yang diterapi dengan antibiotik sefotaksim, seftriakson, ko-amoksiklav. Antihipertensi yang digunakan pada anak umumnya diuretik, angiotensin converting enzyme inhibitors, angiotensin receptor blockers, calcium channel blockers, (amblodipin, nifedipin, isradipin, alpha-symphatetic agents, beta blockers dan vasodilator. Aktivitas fisik tidak perlu dibatasi, dan pada edema ringan atau tidak berat tidak perlu dilarang pergi ke sekolah

  8. Si?ndrome de Burnout y estre?s laboral en profesores

    OpenAIRE

    Barreto E., Marilu? E.

    2013-01-01

    En la u?ltima de?cada la presencia del si?ndrome de Burnout ha ido en aumento muy considerablemente, como una consecuencia de trabajar intensamente hasta el li?mite de no tomar en cuenta las necesidades personales. Esta situacio?n se acompan?a de sentimientos de falta de ayuda, de impotencia, de actitudes negativas y de una posible pe?rdida de autoestima que sufre el trabajador, descrita como si?ndrome de Burnout (Caballero y Milla?n,1999). La prevalencia del si?ndrome de Burnout a nivel i...

  9. EFECTO DE LA ACUPUNTURA EN EL TRATAMIENTO DEL INSOMNIO EN EL SINDROME CLIMATERICO POSTMENOPAUSICO

    OpenAIRE

    GUTIERREZ LOPEZ, ALMA MARGARITA

    2010-01-01

    PALABRAS CLAVE: INSOMNIO, SINDROME CLIMATERICO, ACUPUNTURA. EL INSOMNIO, SEGUN EL MANUAL DIAGNOSTICO Y ESTADISTICO DE TRASTORNOS MENTALES, ES LA DIFICULTAD PARA INICIAR O MANTENER EL SUENO, O NO TENER UN SUENO REPARADOR DURANTE AL MENOS 1 MES. ES UN SINTOMA QUE SE PRESENTA ENTRE EL 20 Y 40 POR CIENTO DE LA POBLACION, AFECTANDO CON MAYOR FRECUENCIA A MUJERES Y ANCIANOS. ESTE PORCENTAJE ES MAYOR ENTRE LA POBLACION DE MUJERES CON SINDROME CLIMATERICO. EL SERVICIO DE CLIMATERIO DEL INSTITUT...

  10. Sindrome disfágica Dysphagic syndrome

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    Ronaldo Mafia Cuenca

    2007-06-01

    Full Text Available INTRODUÇÃO: A disfagia é o principal sintoma das doenças do esôfago e é representada pela dificuldade em deglutir o alimento ingerido no trajeto da orofaringe até o estômago. Ela é queixa comum na prática clínica diária envolvendo várias especialidades na sua investigação. MÉTODOS: Foi realizada revisão atualizada da literatura internacional através do Pubmed (www.pubmed.com e nacional (www.lilacs.br utilizando-se as seguintes palavras-chave: disfagia e transtornos da deglutição. A extensão do tema foi limitado aos seguintes enfoques: etiologia, diagnóstico e exames complementares mais aplicáveis à exploração propedêutica. CONCLUSÃO: Embora a literatura apresente bom entendimento do processo disfágico, no diagnóstico preciso de sua causa há freqüentemente necessidade de múltiplos exames complementares que associados fazem melhor entender o que acomete o paciente e orientará mais adequadamente a conduta a ser tomadaBACKGROUND: Dysphagia is the main symptom of diseases of the esophagus, being manifested by deglutition difficulties, which reaches the oropharynx and stomach pathway. Is a common daily complaint in the clinical practice, involving numerous specialties regarding its investigation. METHODS: An international literature review was made using Pubmed (www.pubmed.com and a national utilizing (www.lilacs.br the following keywords: dysphagia and deglutition disorders. The extension of the subject was limited to the following areas: etiology, diagnosis and complementary exams which were aplicable to exploratory propedeutics. CONCLUSION: Eventhough the literature presents a good understanding of the dysphagic process, the need for multiple complementary exams is frequent during diagnosis, developing a better understanding of what the patient has, adequately orienting which conduct should be taken.

  11. Tata Laksana Kasus Perempuan dengan Pure Gonadal Dysgenesis 46, XY (Sindrom Swyer)

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    Kanadi Sumapradja; Mila Maidarti; Achmad K. Harzif; Budi Wiweko; Gita Pratama; Muharam Natadisastra; Andon Hestiantoro

    2016-01-01

    Disorders of sex development (DSD) adalah kelainan medis yang dikaitkan dengan ketidakcocokan antara kromosom, gonad dan fenotip. Sindrom Swyer adalah kelainan berupa disgenesis gonad 46,XY dan diikuti dengan tidak terjadinya pelepasan anti-mullerian hormone (AMH) dari gonad yang mengalami disgenesis sehingga mengakibatkan berkembangnya duktus muller menjadi uterus. Keadaan tersebut mengakibatkan pasien mengeluh amenorea primer dan organ seks sekunder tidak berkembang. Orientasi gender umumn...

  12. Factores de riesgo para sindrome metabólico en pacientes con higado graso.

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    Uzcátegui, Lilia; Ángel, José Gregorio; Martínez, Dasyl; Gómez Pérez, Roald; Arata de Bellabarba, Gabriela

    2008-01-01

    Editorial. Periodismo, mal periodismo, mal de Chagas y ciencias de la salud. Editorial. Journalism, poor journalim, Chagas disease and health sciences. Salinas, Pedro José Cistoadenoma seroso de ovario y embarazo. Reporte de caso. Ovarian serous cystoadenoma and pregnancy. Case report Terán, Penélope; Uribarri, Carolina; Castillo, Sonia y Salinas, Roberto. Factores de riesgo para sindrome metabólico en pacientes con higado graso. Risk factors of the metabolic syndrome i...

  13. Hubungan Resistensi Insulin dengan Gambaran Klinis Sindrom Ovarium Polikistik

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    Meliza Wahyuni

    2015-09-01

    Full Text Available Abstrak Sindrom Ovarium Polikistik (SOPK merupakan kelainan endokrin dan metabolik pada wanita usia reproduksi. SOPK merupakan kumpulan gejala dari amenore, oligomenore, infertilitas, obesitas, hirsutisme, acne, alopesia, dan akantosis nigrikan. Resistensi insulin diyakini sebagai salah satu penyebab tersering dari SOPK melalui berbagai mekanisme. Tujuan penelitian ini adalah untuk mengetahui hubungan resistensi insulindengan gambaran klinis SOPK. Penelitian ini dilakukan pada pasien SOPK dengan menggunakan studi cross sectional dengan pendekatan retrospektif, yaitu mengumpulkan kejadian masa lalu dari tahun 2009 - 2011, jumlah sampel 105 orang. Analisis statistik yang digunakan adalah uji chi-square. Hasil penelitian didapatkan 33,3% penderita SOPK mengalami resistensi insulin. Berdasarkan gambaran klinis 35,23% amenore, 64,77% oligomenore, 72,04% infertilitas, 50,5% obesitas, 0,95% hirsutisme, acne 20%, alopesia dan akantosis nigrikan0%. Dari 33,3% SOPK dengan resistensi insulin 40% amenore, 60% oligomenore, 71,9% infertilitas, 77,14% obesitas, dan 0% hirsutisme. Berdasarkan hasil uji statistik ditemukan hubungan bermakna antara resistensi insulin dengan obesitas (p<0,05 dan tidak ditemukan hubungan bermakna antara resistensi insulin dengan infertilitas, hirsutisme, dan acne (p>0,05.Kata Kunci: SOPK, resistensi insulin, gambaran klinisAbstract Polycystic Ovary Syndrome (PCOS is an endocrine and metabolic disorders that is common in reproductive-aged women. PCOS is a group of symptoms, such as amenorrhea, oligomenorrhea, infertility, obesity, hirsutism, acne, alopecia, and achanthosis nigricans. Insulin resistance is believed to be one of the most common causes of PCOS through a various mechanisms. The objective of this study was to find out the relationship between insulin resistance and clinical manifestation of PCOS. This research was done in patients with PCOS using cross sectional study with retrospective approach. Data was collected from

  14. Papiledema unilateral na síndrome do pseudotumor cerebral

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    Mário L. R. Monteiro

    1985-06-01

    Full Text Available São apresentadas as fotografias de fundo de olho de 6 mulheres com papiledema unilateral e a síndrome do pseudotumor cerebral. Achados associados foram: obesidade em 5 e a sindrome da sela vazia parcial em 2. São discutidas as possíveis explicações para o desenvolvimento de papiledema unilateral nesses pacientes e que favorecem um mecanismo presente na porção distal dos nervos ópticos.

  15. Radiographic and tomographic aspects of meningeal hemangiosarcoma in a German Shepherd dog with clinical signs of cauda equina sindrome

    International Nuclear Information System (INIS)

    Pinto, A.C.B. de C.F.; Ferrigno, C.R.A.; Matera, J.M.; Torres, L.N.; Sinhorini, I.L.; Cortopassi, S.R.G.; Hage, M.C.F.N.S.

    2007-01-01

    Hemangiosarcoma is a highly malignant neoplasia derived from the endothelial cell line and, therefore, can arise in any tissue with blood vessels. A case of a rare meningeal site of hemangiosarcoma in an eight-year old German Shepherd dog with clinical signs of cauda equina sindrome is described. The diagnosis was made based on clinical, radiographic, tomographic and histopathological findings [pt

  16. La sindrome da vibrazioni mano-braccio : studi epidemiologici e clinici della funzione vascolare e neurosensitiva in coorti di lavoratori esposti a vibrazioni segmentali

    OpenAIRE

    Ronchese, Federico

    2013-01-01

    Premesse: un’elevata esposizione a vibrazioni trasmesse al sistema mano-braccio (hand-transmitted vibration, HTV) è correlata con l’insorgenza di disturbi neurologici, vascolari periferici e osteoarticolari a carico degli arti superiori. Il termine “sindrome da vibrazione mano-braccio” (hand-arm vibration syndrome, HAVS) viene comunemente utilizzato per designare unitariamente il complesso di tali lesioni. La componente vascolare di tale sindrome è rappresentata da una forma secondaria di fen...

  17. Existe importância na utilização de exames de fisiologia ano retal no diagnóstico da sindrome do intestino irritável? Is there importance in the use of anorectal physiologic tests in the diagnosis of the irritable bowel syndrome?

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    Maria Auxiliadora Prolungatti Cesar

    2009-09-01

    Full Text Available INTRODUÇÃO: Em alguns pacientes a síndrome do intestino irritável e a constipação funcional se confundem, principalmente quando o sintoma predominante na síndrome do cólon irritável é a constipação. Dentre os vários exames alguns testes fisiológicos ano retais avaliam a função esfincteriana e sensibilidade retal OBJETIVO: Verificar se existem diferenças entre as manometrias anais dos pacientes com constipação funcional e síndrome do intestino irritável. MÉTODO: Trata-se de estudo de 55 manometrias e testes de sensibilidade anais realizadas em pacientes atendidos no ambulatório de Fisiologia Anal do Serviço de Clínica Cirúrgica do Hospital Universitário de Taubaté com diagnóstico de constipação intestinal ou síndrome do intestino irritável no período de janeiro de 2006 a maio de 2007. Todos os pacientes possuíam colonoscopia a normal e foram incluídos nos critérios diagnósticos de Roma II para Constipação Funcional e Síndrome do Intestino Irritável. As manometrias foram realizadas com aparelho ALACER, de perfusão com 8 canais. RESULTADOS: Não foram encontradas diferenças entre as manometrias quanto às pressões de repouso, contração e evacuação, assim como nos valores de sensibilidade retal. Encontramos diferenças quanto à dor abdominal desencadeada nos pacientes com síndrome do intestino irritável no momento do volume máximo tolerável em que 69,2% destes pacientes apresentaram dor abdominal. CONCLUSÃO: Os pacientes com a síndrome do intestino irritável apresentam dor à distensão da ampola retal, que não ocorre nos pacientes constipados, na aferição do volume máximo tolerável, não houve diferença em relação aos outros dados da manometria.INTRODUCTION: In some patients the irritable bowel syndrome and the functional constipation is confuse, mainly when the predominant symptom in the irritable bowel syndrome is the constipation. Amongst some examinations the anal manometry

  18. Nonhomogeneous immunostaining of hyaline membranes in different manifestations of diffuse alveolar damage Imunomarcação não homogênea das membranas hialinas na sindrome da angustia respiratório do adulto pulmonar, extrapulmonar e idiopática

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    André Peres e Serra

    2006-01-01

    extrapulmonar (DADexp (n=9 constituído por casos de sepse e choque séptico e (c dano alveolar difuso idiopático (DADi (n=9 constituído por casos idopáticos (ou pneumonia intersticial aguda. As características das membranas hialinas do padrão histológico de dano alveolar difuso foram examinadas usando vários tipos de anticorpos. Os anticorpos usados foram surfactante apoproteina A (SP-A, anti-citokeratina 7 (CK7, citokeratina 8 (CK8, alfa actina de músculo liso (a-SMA, citokeratina AE1/AE3 (AE1/AE3 e antígeno relacionado ao fator VIII (Fator VIII. RESULTADOS: Observaram-se aumentos maiores da quantidade de membrana hialina no dano alveolar difuso pulmonar (12.65 ± 3.24%, intermediários no dano alveolar difuso extrapulmonar (9.52 ± 3.64% e baixos no dano alveolar difuso idiopático (7.34 ± 2.11% respectivamente, esta diferencia foi estatística significante entre o dano alveolar difuso pulmonar e o dano alveolar difuso idiopático (p<0.05. Não se encontrou significância estatística para a quantidade de imunomarcação de Sp-A nos grupos de dano alveolar difuso pulmonar (15.36 ± 3.12%, extrapulmonar (16.12 ± 4.58% e idiopático (13.74 ± 4.20%. Com relação ao Fator VIII, nós encontramos maiores aumentos da imunomarcação da membrana hialina no grupo dano alveolar difuso idiopático (14.12 ± 6.25% do que no dano alveolar difuso extrapulmonar (3.93 ± 2.86%, com significância estatística (p<0.001. Da mesma forma houve um aumento progressivo da imunomarcação da membrana hialina com citokeratina AE1/AE3 nos grupos de dano alveolar difuso extrapulmonar (5.42 ± 2.80% e dano alveolar difuso idiopático (0.47 ± 0.81% (p<0.001. Nenhuns dos grupos marcou para as citokeratina CK-7, CK-8 ou para a vimentina ou actina de músculo liso. CONCLUSÕES: Este estudo só mostra os componentes epitelio/endotelio (SP-A, Fator VIII e AE1/AE da barreira alvéolo/capilar que estão presentes na formação da membrana hialina nos três diferentes grupos, sugerindo que as

  19. Sindrom metaboličke inzulinske rezistencije i metabolizam ugljikohidrata

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    Metelko, Željko; Crkvenčić, Neva

    2004-01-01

    Stanje metaboličke inzulinske rezistencije jest nemogućnost ostvarenja biološkog učinka inzulina u koncentracijama koje su učinkovite u zdravih osoba. Utjecaj se primjećuje na metabolizmu glukoze, metabolizmu lipida, funkciji krvnih žila i trombocita te regulaciji autonomnoga živčanog sustava. Fizička neaktivnost, nepravilna prehrana i sedentarni način života značajno pridonose razvoju pretilosti, metaboličke inzulinske rezistencije i tipa 2 šećerne bolesti. Metaboličk...

  20. HUBUNGAN ANTARA SINDROM MENOPAUSE DENGAN KUALITAS HIDUP PEREMPUAN MENOPAUSE DI PUSKESMAS SUKAHAJI KABUPATEN MAJALENGKA

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    Ruri Yuni Astari

    2015-01-01

    because it is normal for a woman are especially needed.Keywords : Menopausal Syndrome, Quality of Life, MajalengkaAbstrakMenopause merupakan fase alamiah yang dialami oleh setiap perempuan, merupakan proses reproduksi yang ditandai berakhirnya masa subur seorang perempuan karena ovarium sudah tidak menghasilkan hormon estrogen dan progesteron, sehingga menimbulkan berbagai keluhan menopause yang disebut sebagai sindrom menopause. Masalah atau perubahan yang dialami perempuan menopause akan menimbulkan suatu krisis yang akan mempengaruhi kualitas hidup. Tujuan penelitian untuk menganalisis hubungan antara sindrom menopause dengan kualitas hidup. Metode penelitian dilakukan secara observasional analitik dengan rancangan potong lintang. Populasi adalah perempuan yang telah menopause selama 1–2 tahun di wilayah Puskesmas Sukahaji Kabupaten Majalengka dan memenuhi kriteria penelitian, yaitu masih mempunyai suami, sudah tidak mengalami haid selama 1-2 tahun dan mampu membaca.Teknik pengambilan sampel dilakukan secara total sampling, dilaksanakan bulan Februari sampai dengan Maret 2013. Sindrom menopause diukur menggunakan kuesioner MSQ (Menopause Symptom Questionaire dan kualitas hidup diukur menggunakan kuesioner (WHOQOLBREFThe World Health Organization Quality Of Life. Data di analisis secara statistik univariat, bivariat dan multivariat. Hasil penelitian menunjukkan adanya hubungan negatif kuat antara sindrom menopause aspek fisiologis dan psikologis dengan kualitas hidup (r= -0,786 p=0,000 dan r= -0,706 p=0,000, hubungan negatif kuat secara simultan sindrom menopause  aspek  fisiologis  dan  psikologis  dengan  kualitas  hidup  perempuan  (r=  -0,772,  p =0,000, hubungan bermakna antara penghasilan dan pendidikan dengan kualitas hidup (r= -0,313 p=0,011 dan r= -0,359 p=0,003. Paritas tidak berhubungan bermakna dengan kualitas hidup perempuan menopause. Simpulan: sindrom menopause berdampak pada penurunan kualitas hidup perempuan menopause. Perlunya memberikan

  1. Tata Laksana Kasus Perempuan dengan Pure Gonadal Dysgenesis 46, XY (Sindrom Swyer

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    Kanadi Sumapradja

    2016-06-01

    Full Text Available Disorders of sex development (DSD adalah kelainan medis yang dikaitkan dengan ketidakcocokan antara kromosom, gonad dan fenotip. Sindrom Swyer adalah kelainan berupa disgenesis gonad 46,XY dan diikuti dengan tidak terjadinya pelepasan anti-mullerian hormone (AMH dari gonad yang mengalami disgenesis sehingga mengakibatkan berkembangnya duktus muller menjadi uterus. Keadaan tersebut mengakibatkan pasien mengeluh amenorea primer dan organ seks sekunder tidak berkembang. Orientasi gender umumnya adalah sebagai perempuan, karena kurangnya paparan hormon androgen terhadap otak. Tatalaksana kasus Disorders of sex development (DSD sangat mementingkan pasien (patient-centered sehingga tatalaksana medikamentosa maupun pembedahan harus berdasarkan pemahaman pasien terhadap orientasi gendernya. Pada makalah ini dilaporkan kasus sindrom swyer pada seorang perempuan usia 29 tahun dengan keluhan amenorea primer. Hasil analisis kromosom 46,XY (20 metafase dengan hormon follicle stimulating hormone (FSH 31.5miu/ml, luteinizing hormone (LH 10.8miu/ml, estradiol (E2 <5pg/ml, testosteron total (T <0.0025ng/ml. Tatalaksana medikamentosa adalah memberikan terapi hormon estrogen untuk membantu proses feminisasi. Karena risiko tinggi terjadinya tumor pada kasus disgenesis gonad intra-abdomen dengan kromosom Y, maka direncanakan tindakan gonadektomi. Kata kunci: Tatalaksana, Sindrom Swyer, pure gonadal dysgenesis Case Management of Pure Gonadal Dysgenesis 46, XY (Sindrom Swyer Abstract Disorders of sex development (DSD are medical conditions in which the development of chromosomal, gonadal or anatomic sex varies from normal and may be incongruent with each other. Swyer syndrome is a condition caused by pure gonadal dysgenesis 46,XY, which followed by inadequate anti-mullerian (AMH production results in maintenance and further development of mullerian duct into uterus. Therefore, many patients who suffer from this condition initially come with chief complaint of primary

  2. Estados de mal epiléptico na sindrome Delennox-Gastaut: aspectos terapeuticos

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    José Geraldo Speciali

    1977-09-01

    Full Text Available Foram descritas as condutas terapêuticas utilizadas nos estados de mal epiléptico, convulsivos e não convulsivos, observados em 14 pacientes com síndrome de Lennox-Gastaut. Verificou-se relação temporal entre aparecimento de estado de mal epiléptico e início de tratamento com clonazepam e difenilhidantoina; a retirada dessas medicações foi seguida pelo desaparecimento dos estados de mal. Indicou-se a possibilidade de tratamento dos estados de mal epiléptico modificando-se o esquema terapêutico administrado por via oral, reservando-se o tratamento parenteral para os estados com comprometimento progressivo da consciência e/ou dos distúrbios neurovegetativos.

  3. A Sindrome de Burnout(SB em docentes do ensino superior de instituições privadas de Santarém, PA

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    Loreni Bruch Dutra

    2016-11-01

    Full Text Available A Sindrome de Burnout implica em diversas consequências sociais e afeta negativamente a qualidade de vida do docente e do trabalho desenvolvido. Compreende as seguintes dimensões: Ilusão pelo trabalho, Desgaste psíquico, Indolência e Culpa. O objetivo deste artigo foi estudar a Síndrome de Burnout (SB em docentes das instituições privadas de ensino superior de Santarém-PA e sua relação com características demográficas, laborais e estilo de vida. Foi realizado estudo transversal com 311 docentes das áreas da saúde, exatas e humanas. Utilizou-se o instrumento autoaplicável, Cuestionario para la Evaluación del Síndrome de Quemarse por el Trabajo-CESQT, e regressão linear múltipla para o estudo de cada uma das quatro dimensões da SB. Os resultados mostraram que tempo de docência e tempo de docência na instituição; qualidade da relação com chefias, colegas e alunos; presença de recursos necessários para o trabalho; desejo de mudar de profissão e percepção de saúde foram algumas das características que estiveram relacionados com as dimensões da SB. Portanto, necessita-se de investimentos em políticas institucionais que visem a melhoria da qualidade de vida do docente nas suas funções laborais e investimentos nas condições de trabalho.

  4. Sindrome de apnea obstructiva del sueño y alteración en la tolerancia a la glucosa

    OpenAIRE

    Verner, Codoceo R.

    2013-01-01

    La disminución del riesgo cardiovascular sigue siendo uno de los objetivos principales de la Salud Pública. Contribuyen a él patologías como la Diabetes Mellitus, Obesidad e Hipertensión Arterial, todas las cuales no han logrado ser detenidas en su creciente prevalencia. Existen factores hasta ahora no considerados en forma integral al tratamiento de esta triada, como el Sindrome de Apnea Obstructiva del Sueño, que se sabe está asociado a éstas, plantea la idea de un tratamiento sinérgico com...

  5. Sindrome de apnea obstructiva del sueño y alteración en la tolerancia a la glucosa

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    Codoceo R. Verner, Dr.

    2013-05-01

    Full Text Available La disminución del riesgo cardiovascular sigue siendo uno de los objetivos principales de la Salud Pública. Contribuyen a él patologías como la Diabetes Mellitus, Obesidad e Hipertensión Arterial, todas las cuales no han logrado ser detenidas en su creciente prevalencia. Existen factores hasta ahora no considerados en forma integral al tratamiento de esta triada, como el Sindrome de Apnea Obstructiva del Sueño, que se sabe está asociado a éstas, plantea la idea de un tratamiento sinérgico como alternativa para lograr las metas terapéuticas. Sin embargo las expectativas creadas no concuerdan con los resultados comunicados, demostrándose que faltan aún estudios que realizar. Se mencionan diversos estudios epidemiológicos y se resumen los fundamentos biológicos que explican la asociación SAOS - DM.

  6. Sindrom Koroner Akut dengan Komplikasi Udem Paru Akut dan Henti Jantung

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    Eka Fithra Elfi

    2015-05-01

    Full Text Available Abstrak Salah satu manifestasi sindrom koroner akut yang banyak terjadi adalah non ST elevation segment ofmyocardial infarction (NSTEMI. NSTEMI dapat menimbulkan berbagai komplikasi seperti udem paru akut, hentijantung, bahkan kematian. Dilaporkan seorang pasien wanita 53 tahun dengan diagnosis NSTEMI. Pasien mengalamihenti jantung dan udem paru akut yang merupakan gagal jantung akut. Henti jantung pada pasien ini diawali  oleharitmia maligna yang disebabkan oleh kurangnya asupan oksigen pada otot jantung. Pasien memerlukanpenatalaksanaan multidisiplin dan intensif. Pada pasien diberikan dukungan ventilasi mekanik dengan tekanan positifyaitu CPAP untuk mengurangi mortalitas edema paru. Selain itu diperlukan pemantauan ketat hemodinamik danasupan nutrisi pada pasien. Selain masalah jantung dan paru, pada pasien juga terjadi penurunan kesadaran setalahhenti jantung. Gangguan pada sistem saraf pusat merupakan penyebab kematian yang cukup tinggi pada pasien yangselamat dari henti jantung dan resusitasi. Berdasarkan hal itu, perlu dilakukan resusitasi kardioserebral pada pasiendengan henti jantung. Perbedaan utama dengan resusitasi jantung paru adalah pentingnya manajemen j alan nafasyang lebih lengkap dengan ventilasi mekanik.Kata kunci: NSTEMI, henti jantung, udem paru akut Abstract One manifestation of acute coronary syndrome is the case is non-ST segment elevation of myocardial infarction(NSTEMI. NSTEMI may cause various complications: an acute pulmonary edema, cardiac arres, and even death.Reported a 53 years old female patient with a diagnosis of NSTEMI. The patient had a cardiac arrest and acutepulmonary edema is acute heart failure. Cardiac arrest in this patient initiated by malignant arrhythmias caused by lackof oxygen to the heart muscle. Patients require multidisciplinary and intensive management. In patients receivedmechanical ventilatory support with positive pressure that CPAP to reduce the mortality of pulmonary edema. Alsorequired

  7. Hallervorden Spatz syndrome: magnetic resonance findings. Case report; Sindrome de Hallervorden Spatz: achados na ressonancia magnetica. Relato de caso

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    Farage, Luciano; Castro, Mario Augusto Padula; Macedo, Tulio Augusto Alves [Universidade Federal de Uberlandia, MG (Brazil). Hospital de Clinicas. Setor de Radiologia; Assis, Marcelo Cardoso de [Universidade Federal de Uberlandia, MG (Brazil). Faculdade de Medicina. Dept. de Cirurgia; Souza, Lincoln Pereira de; Freitas, Luiz Oliveira de [Universidade Federal de Uberlandia, MG (Brazil). Dept. de Clinica Medica

    2004-09-01

    Hallervorden-Spatz syndrome is a neuro degenerative disease, autosomic recessive with two clinical features: early and late onset. Psychiatric, pyramidal and extrapyramidal signs are present in the late subtype. We report the case of a 41-old woman with extrapyramidal signs. Magnetic resonance imaging (MRI) showed the eye-of-the-tiger sign in the medial globus pallidus. This is due to a gliosis (increased signal) and accumulation of surrounding iron (decreased signal intensity) in long T R sequences. There is a strong relationship between MRI findings and the gene mutation responsible for this disease. It makes the MRI sensible for diagnosing this syndrome. (author)

  8. AIDS related thoracic lymphoma: evaluation by computed tomography; Linfoma toracico na sindrome da imunodeficiencia adquirida: avaliacao por tomografia computadorizada

    Energy Technology Data Exchange (ETDEWEB)

    Siciliano, Antonio Alexandre de Oliveira [Hospital Universitario Clementino Fraga Filho, Rio de Janeiro, RJ (Brazil). Servico de Radiodiagnostico; Marchiori, Edson [Universidade Federal, Rio de Janeiro, RJ (Brazil). Curso de Pos-graduacao em Radiologia

    2000-02-01

    The authors reviewed five cases of patients with acquired immunodeficiency syndrome (AIDS) related lymphoma to describe the thoracic findings on computed tomography. The patients were followed at Hospital Universitario Clementino Fraga Filho, Hospital Universitario Antonio Pedro and Hospital da Lagoa, from November, 1989 to March 1998. Epidemiological, clinical and pathological data from these patients were quiet variable and pulmonary nodules and masses, hilar and mediastinal lymphadenopathy, and thoracic wall masses were observed. AIDS related lymphomas involving the chest are pleomorphic and most commonly extranodal. (author)

  9. Pancreatite esclero-gomosa simulando sindrome cancerosa da cabeça do pâncreas

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    A. Penna de Azevedo

    1944-06-01

    Full Text Available Em um homem de 49 anos de idade, observou-se um sindrome de tumor da cabeça do pâncreas. Realizada a intervenççao cirúrgica foi verificada a presença de uma formaão dura de aspecto fibroso, medindo 9 x 7,5 x 6,5 cm. O exame microscópico mostrou tratar-se de uma pancreatite indurativa associada à presença de gomas miliares, infiltração de eosinófilos e lesões produtivas dos vasos sanguíneos, correspondendo ao aspecto dos processo esclerogomosos sifilíticos do pâncreas.A tumor of the head of the pancreas is reported ina a male, 49 years old, which corresponded to a nodule of fibrous tissue measuring 9 x 7,5 x 6,5 cm. Microscopically, a chronic interstitial pancreatitis associated to miliary gummata, eosinophilic infiltration and proliferation of blood vessels was found and the diagnosis of siphilitic pancreatitis was done.

  10. Sindrome de Lennox-Gastaut com inicio tardio: I - frequencia de casos com inicio anterior e ulterior aos 6 anos de idade, fatores etiologicos e nivel intelectual

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    Amilton Antunes Barreira

    1980-12-01

    Full Text Available De um grupo de 66 pacientes com sindrome de Lennox Gastaut, 15 apresentaram as primeiras manifestações clinicas após os 6 anos de idade. Desses, 12 foram acompanhados durante o período médio de 2 anos e 6 meses, com avaliações neurológicas a intervalos de cerca de 2 meses. A revisão das publicações pertinentes permitiu estabelecer que em 20% das casuisticas apreciadas a sindrome de Lennox-Gastaut se inicia após o 6° ano de vida. As avaliações clinicas permitiram verificar que nosos pacientes apresentaram incidência de lesões neurológicas graves precedendo a instalação da síndrome por vários anos. As avaliações psicométricas evidenciaram intenso comprometimento do nível intelectual em contraste com os dados da literatura sobre a síndrome de Lennox-Gastaut de início tardio.

  11. Sindrome de russel tumor diencefálico em uma criança

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    Luiz A. C. Roxo da Motta

    1990-03-01

    Full Text Available Apresenta-se o caso de criança do sexo masculino com síndrome de Russel devida a astrocitoma pilocítico localizado na região diencefálica. O diagnóstico foi realizado aos 16 meses de idade, mas sua sintomatologia se iniciou aos 4 meses, com emagrecimento progressivo. À internação apresentava-se com peso de 6150g e 74cm de estatura, emaciada, sem panículo adiposo, irritadica e com sinais de hipertensão intracraniana. Existia estrabismo convergente, nistagmo vertical do olho esquerdo e papiledema bilateral. Os reflexos tendinosos eram exaltados e tinha tetraparesia espástica. A avaliação endócrina demonstrou aumento basal do GH (23 ng/ml, do TSH (6,2 mUI/l e da prolactina (26 ng/ml. Os dois primeiros hormônios não responderam ao teste agudo com o TRH, enquanto a prolactina teve resposta pobre. Foi submetida a radioterapia com acelerador linear (dose total de 4000 rads e a cirurgia, na qual não se conseguiu extirpar todo o tumor, devido a seu tamanho. Nove meses após, a criança encontra-se bem, com apreciável ganho ponderai (2500g.

  12. A sindrome da tensão pre-menstrual : uma abordagem psicanalitica

    OpenAIRE

    Vera Aparecida de Carvalho Zoldan

    2001-01-01

    Resumo: O interesse por esta pesquisa orienta-se sobre as questões surgidas na clinica psicanalítica a partir do atendimento de pacientes vítimas da Síndrome da Tensão Pré-Menstrual (STPM) e suas manifestações sintomáticas, não somente físicas, mas predominantemente psíquicas. Embora seja considerada pela Medicina como uma doença resultante das próprias alterações orgânicas e hormonais associadas ao ciclo reprodutor feminino, a análise psicanalítica revela a existência de relações particularm...

  13. Os trigonum tarsi syndrome. Magnetic Resonance features; Sindrome dell'os trigonum tarsi. Ruolo della Risonanza Magnetica

    Energy Technology Data Exchange (ETDEWEB)

    Iovane, A.; Finazzo, M.; Carcione, A.; De Maria, M; Lagalla, R. [Palermo Policlinico Univ. P. Giaccone, Palermo (Italy). Ist. di Radiologia; Midiri, M. [Bari Policlinico Univ., Bari (Italy). Ist. di Radiologia

    2000-02-01

    aspect of the tibia, or hypo mobility to pseudoarthrosis. Forced plantar flexion acquisitions are particularly useful in this condition because can demonstrate the mechanism of injury. [Italian] L'os trigonum tarsi e' un osso accessorio del piede localizzato in sede posterolaterale rispetto al tubercolo esterno dell'astragalo e di solito non da' alcuna sintomatologia. In particolari condizioni, che comportano sollecitazioni o microtraumi ripetuti nel tempo a livello del retropiede puo' essere responsabile di talalgia posteriore realizzando la cosidetta sindrome dell'os trigonum tarsi. Il dolore e' localizzato nella sede preachillea. La diagnosi tuttavia risulta particolarmente complessa i quanto numerose altre forme patologiche si manifestano con la medesima sintomatologia clinica. Con la radiologia tradizionale e' possibile dimostrare la presenza dell'os trigonum e le sue eventuali alterazioni morfo-strutturali. La RM (Risonanza Magnetica) di contro consente non solo di identificare le alterazioni strutturali dell'osso ma anche di riconoscere le lesioni associate dei tessuti molli. Sono stati studiati con RM nove pazienti affetti da sindrome dell'os trigonum tarsi. I pazienti sono stati esaminati nella posizione supina con il piede in posizione indifferente e successivamente bloccato nella flessione plantare. Lo studio e' stato condotto con magnete superconduttivo da 0,5 T impiegando una bobina dedicata per le estremita'. Sono state utilizzate sequenze spin-echo T1, gradient-echo T2* e fast inversion recovery secondo piani di scansione assiali e saggitali. In tutti i pazienti esaminati sono state valutate: sede e morfologia dell'os trigonum; caratteristiche dell'intensita' del segnale delle strutture ossee, cartilaginee e dei tessuti adiacenti; presenza di eventuali lesioni tendinee associate. Non sono state osservate anomalie di sede ne' di forma dell'os trigonum. L

  14. Sindrome de Sturge – Weber - Os síndromes raros também existem

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    Cátia Canelas

    2015-12-01

    Recorreu ao serviço de urgência por crises convulsivas tónico-clónicas generalizadas quase diárias desde há 1 mês. Ao exame físico o doente apresentava-se pouco colaborante mas hemodinamicamente estável. Ao nível da cabeça eram evidentes diversas alterações: macrocefalia, hipertrofia dos tecidos moles da face com manchas em vinho do porto exuberantes bilaterais com distribuição oftálmica, maxilar e mandibular do nervo trigémio, e hemangiomas conjuntivais bilaterais (Fig. 1. Ao exame neurológico apresentava hemiparesia esquerda grau 3/5 em ambos os membros. Realizou tomografia computorizada crânio-encefálica que mostrou atrofia do hemisfério encefálico direito com calcificação cortical de configuração giriforme de predomínio frontal e occipital e maior volume do plexo coroide do ventrículo lateral direito (Fig.2, aspetos descritos na literatura como característicos de SSW4. Analiticamente sem alterações nomeadamente da função tiroideia. O doente foi observado por oftalmologia tendo sido diagnosticado glaucoma bilateral com perda visual acentuada. Trata-se então de um caso de síndrome de Sturge-Weber tipo I (angiomas da face e das leptomeninges e glaucoma segundo a The Roach Scale, que por falta de seguimento médico apresentava as diversas complicações da síndrome não controladas, convulsões frequentes, perda visual acentuada, história de episódios semelhantes a AVC com hemiparésia sequelar, cefaleias, défice cognitivo e isolamento social. Apesar da forma de apresentação grave com sintomas desde a infância o diagnóstico foi estabelecido numa idade muito pouco comum. A síndrome de Sturge-Weber é uma entidade a ter presente no diagnóstico diferencial das manchas vinho do porto e das crises convulsivas. O diagnóstico precoce e o seguimento/vigilância médica apertada são as únicas formas de melhorar o prognóstico sombrio das manifestações e complicações desta síndrome que são verdadeiramente limitadoras de

  15. Hubungan Kadar Glukosa Darah Saat Masuk Rumah Sakit Dengan Lama Hari Rawat Pasien Sindrom Koroner Akut (SKA Di RSUP Dr. M. Djamil Padang

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    Rosi Oktarina

    2013-05-01

    Full Text Available AbstrakHiperglikemia masih menjadi topik penelitian yang sering dihubungkan dengan kejadian sindrom koroner akut (SKA di dunia, terutama hiperglikemia saat masuk rumah sakit. Hal ini didasari oleh beberapa pengaruh kadar glukosa darah yang tinggi terhadap sistem kardiovaskuler seperti gangguan fungsi ventrikel kiri, stroke volume yang menurun, regurgitasi katup mitral berulang, gangguan pada waktu pengisian diastolik hingga risiko tinggi untuk arritmia, serta hubungannya dengan peningkatan risiko trombosis. Sehingga semakin memperjelas pengaruh hiperglikemia yang tidak hanya dapat meningkatkan risiko terjadinya SKA, melainkan juga dapat memperburuk kondisi pasien SKA sendiri. Penelitian ini bertujuan mengidentifikasi hubungan kadar glukosa darah sewaktu dengan lama hari rawat pasien Sindrom Koroner Akut (SKA. Jenis penelitian yang digunakan adalah penelitian analitik dengan menggunakan desain penelitian Cross Sectional Study. Penelitian ini menggunakan data sekunder yang diambil di Instalasi Rekam Medik (Medical Record, yakni data rekam medik pasien yang didiagnosis sebagai Sindrom Koroner Akut (SKA yang dirawat inap di Rumah Sakit Umum Pusat DR. M. Djamil Padang Periode Januari–Desember 2011. Ditemukan sebagian besar pasien SKA masuk rumah sakit dengan kadar Glukosa Darah Sewaktu (GDS sebesar ≥ 200 mg/dl (40% dan lama hari rawat sebesar ≥ 7 hari (52%. Dari hasil analisa bivariat dengan menggunakan uji korelasi Spearman ditemukan adanya hubungan searah antara kadar glukosa darah saat masuk rumah sakit dengan lama hari rawat pasien SKA dengan kekuatan hubungan yang sedang, r = +0,492, p = 0, 000 (p<0,05. Pemantauan terhadap kadar GDS yang diperiksa saat pasien masuk rumah sakit perlu dilakukan dan untuk penelitian yang akan datang diharapkan dapat diteliti lebih lanjut faktor-faktor lain yang mempengaruhi lama hari rawat pasien SKA.Kata kunci: Kadar glukosa darah saat masuk RS, lama hari rawatAbstractHyperglicemia is still become a research

  16. L' influenza nella regione Lazio dal 1999 al 2003: casi di sindrome influenzale, ricoveri ospedalieri per malattie respiratorie e coperture vaccinali

    Directory of Open Access Journals (Sweden)

    A. Pasquarella

    2003-05-01

    Full Text Available

    Obiettivi: 1 Descrivere l’andamento dei ricoveri ospedalieri per patologie respiratorie acute e croniche concomitanti alle epidemie stagionali da virus influenzale dal 1999 al 2003, in relazione con la segnalazione dei casi di sindrome influenzale (ILI da parte dei medici sentinella. 2 Misurare l’eccesso dell’ospedalizzazione influenza-correlata nelle diverse fasce di età rispetto ai periodi non epidemici. 3 Analizzare le modificazioni del ricorso al ricovero ospedaliero in relazione al tasso di copertura della vaccinazione antinfluenzale nella popolazione anziana, su scala regionale e nelle diverse ASL.

    Metodi: sono stati estratti dal Sistema Informativo
    Ospedaliero i ricoveri per patologie respiratorie
    influenza-correlate (codici ICD9-CM: 480-487; 460-
    466; 490-496 relativi agli anni 1999-2003.
    L’incidenza di ILI è stata stimata sulla base delle
    segnalazioni dei medici sentinella afferenti alla
    rete FLU-ISS dell’Istituto Superiore di Sanità.

    Per il calcolo dei tassi di copertura è stato utilizzato l’archivio
    nominativo dei soggetti vaccinati contro l’influenza,
    attivo nella regione Lazio dal 1999. Nel periodo considerato sono stati messi in relazione i tassi di ospedalizzazione età-specifici, le incidenze di ILI e le coperture vaccinali. L’eccesso di ospedalizzazione è stato misurato confrontando i tassi relativi ai periodi epidemici e non epidemici.

    Risultati: i tassi di ospedalizzazione per malattie respiratorie sono risultati costantemente superiori nei periodi di maggiore circolazione virale, in particolare negli ultrasessantaquattrenni. Con il progressivo aumento del tasso di copertura vaccinale regionale (da circa il 25% della stagione 1999-2000 a oltre il 60% della stagione 2002-2003 non si è registrata una corrispondente diminuzione dei ricoveri ospedalieri per patologie influenza-correlate.
    L

  17. SINDROME KID: ABORDAJE INTERDISCIPLINARIO

    Directory of Open Access Journals (Sweden)

    Carla De Negri

    Full Text Available Se presenta el caso clínico, de una niña de 2 años de edad, nacida en el Centro Hospitalario Pereira Rossell, portadora del Síndrome KID. Se trata de una displasia congénita ectodérmica caracterizada por la asociación de queratitis, ictiosis y sordera. Es producida por un desorden autosómico dominante, esporádico. Algunos autores lo refieren asociado a la presencia de alteraciones estructurales de órganos dentarios, del tipo hipoplasia e hipomineralización del esmalte y también a gingivitis y candidiasis a nivel de la mucosa bucal. La intervención oportuna del odontopediatra, integrando el equipo de salud, brinda un aporte importante, en la búsqueda de estrategias terapéuticas adecuadas al paciente y al contexto asistencial. El abordaje de tratamiento en pacientes portadores del Síndrome KID debe ser multidisciplinario, requiriendo en niños, la integración de un equipo de salud con pediatra, dermatólogo, oftalmólogo, otorrinolaringólogo y odontopediatra

  18. Sindrom diabeticheskoy stopy

    Directory of Open Access Journals (Sweden)

    Mikhail Borisovich Antsiferov

    2001-06-01

    Full Text Available Поражения нижних конечностей у больных сахарным диабетом (СД касаются врачей различных специальностей. Это связано с тем, что нарушение углеводного обмена приводит к изменениям периферического кровотока, иннервации, развитию трофических язв, а в ряде случаев к необходимости ампутации конечности. Хроническая гипергликемия утяжеляет течение и усложняет лечение язвенных дефектов другого генеза (посттромбофлебитический синдром, липоидный некробиоз, экзема и др.. Все это определяет необходимость точной диагностики, дифференциации и выбора адекватного лечения в каждом случае развития трофического нарушения кожи нижних конечностей. Синдром диабетической стопы объединяет патологические изменения периферической нервной системы, артериального и микроциркуляторного русла, костно-суставного аппарата, которые представляют непосредственную угрозу развития язвеннонекротических процессов и гангрены стопы. Несмотря на достаточный объем информации по патогенезу, диагностике, методам лечения и профилактики осложнений СД, данные по частоте и исходу поражений нижних конечностей по-прежнему остаются неутешительными. Настоящий обзор освещает современное представление о патогенезе, способах лечения и профилактике развития синдрома диабетической стопы.

  19. Freqüência da mutação gene da síndrome do estresse suíno e sua associação com características reprodutivas em marrãs híbridas Frequency of the porcine stress sindrome gene mutation and its association with reproductive traits in crossbred gilts

    Directory of Open Access Journals (Sweden)

    Simone Eliza Facioni Guimarães

    1999-01-01

    Full Text Available O objetivo deste trabalho foi determinar a freqüência do gene causador da síndrome do estresse em suíno (PSS e sua associação com características reprodutivas em marrãs híbridas. Setenta e duas marrãs híbridas Landrace x Large White, provenientes de granjas comerciais localizadas na região de Ponte Nova - Minas Gerais, foram analisadas para a presença da mutação PSS. No diagnóstico da mutação feito por reação em cadeia da polimerase - polimorfismo de comprimento de fragmentos de restrição (PCR-RFLP, o fragmento de 659pb do gene ryr-1 foi amplificado e, nos mutantes a substituição de citosina por timina, que acarreta mudança de aminoácidos da proteína madura de arginina para cisteína nos animais afetados, foi identificado. Dados relativos ao número de leitões nascidos vivos, leitões nascidos com baixa viabilidade e leitões natimortos por leitegada, peso médio dos leitões ao nascer e repetições de cio foram analisados. Do total de marrãs analisadas, foram encontradas 13,88% de marrãs heterozigotas e nenhuma homozigota recessiva. Não houve efeito dos genótipos sobre as características analisadas.The objective of this work was to determine the frequency of the porcine stress sindrome (PSS gene mutation and its association with reproductive traits in crossbred gilts. Seventy two crossbred Landrace x Large White females from commercial farms of Ponte Nova region location - Minas Gerais State, were analyzed for the PSS mutation. The mutation diagnose was made by polimerase chain reaction - restriction fragment length polimorphism, where the 659pb fragment from the ryr-1 gene was amplifyied, and in the mutants the substitution of cytosine by thimine, that leads to the change in the mature protein amino acids from arginine to cysteine in the affected animals, was identified. Data relative to the number of piglets born alive, born alive with low viability and dead piglets per litter, average piglets born weight and

  20. Magnetic resonance imaging findings in patients with Hallervorden-Spatz syndrome; Achados de ressonancia magnetica na sindrome de Hallervorden-Spatz

    Energy Technology Data Exchange (ETDEWEB)

    Nomura, Cesar Higa; Lima, Eduardo Carneiro; Cerri, Giovanni Guido; Leite, Claudia da Costa [Sao Paulo Univ., SP (Brazil). Faculdade de Medicina. Dept. de Radiologia; Rosemberg, Sergio [Sao Paulo Univ., SP (Brazil). Faculdade de Medicina. Dept. de Patologia

    2003-12-01

    The objective of this study was to review the magnetic resonance imaging findings in patients with Hallervorden-Spatz syndrome. We evaluated eight patients with Hallervorden-Spatz syndrome using magnetic resonance imaging. The protocol included at least sagittal and axial T1-weighted images and axial and coronal T2-weighted images. Intravenous gadolinium was administered in a dose of 0.1 mmol/kg. Post-enhanced images were obtained at least in the axial and coronal planes. The results were: all patients presented a bilateral and symmetrical 'tiger-eye signal' on T2-weighted images, corresponding to central hyperintensity and peripheral hypointensity in the globi pallidus. FLAIR and diffusion images showed similar abnormalities. There was no gadolinium enhancement in any of the cases. We concluded that magnetic resonance imaging findings in patients with Hallervorden-Spatz syndrome are very typical and allow the diagnosis of the disease. (author)

  1. Bronchogenic carcinoma in acquired immunodeficiency syndrome - report of two cases; Carcinoma broncogenico na sindrome da imunodeficiencia adquirida - relato de dois casos

    Energy Technology Data Exchange (ETDEWEB)

    Siciliano, Antonio Alexandre de Oliveira [Hospital Universitario Clementino Fraga Filho, Rio de Janeiro, RJ (Brazil). Servico de Radiodiagnostico; Melo, Alessandro Severo Alves de; Marchiori, Edson [Universidade Federal Fluminense, Niteroi, RJ (Brazil). Dept. de Radiologia

    1999-12-01

    The authors report two cases of bronchogenic carcinoma in patients with acquired immunodeficiency syndrome. The first patient, a ee-year-old male, developed a left hilar adenocarcinoma, with spleen and bilateral adrenal metastases. The disease progressed unfavourably, resulting in the patient's death in less than a month. The second patient, a 47-year-old male, developed a large mass in the left upper lobe, with invasion of the thoracic wall and destruction of adjacent ribs. The histopathologic study revealed a non-oat-cell carcinoma. Both patients received palliative treatment since diagnosis was established late in the course of the disease. Recent studies suggest an association between bronchogenic carcinoma and human immunodeficiency virus infection. However, an actual increase in the prevalence of bronchogenic carcinoma in HIV-positive patients remains controversial. (author)

  2. Thoracic manifestations of Kaposi`s sarcoma in AIDS: radiological findings; Manifestacoes toracicas do sarcoma de Kaposi na sindrome da imunodeficiencia adquirida: aspectos radiologicos

    Energy Technology Data Exchange (ETDEWEB)

    Marchiori, Edson [Universidade Federal Fluminense, Niteroi, RJ (Brazil). Dept. de Radiologia; [Universidade Federal, Rio de Janeiro, RJ (Brazil); Baptista, Maria Ines Garcia; Cardenas, Gloria Pamela; Costa Praxedes, Marcia da [Universidade Federal Fluminense, Niteroi, RJ (Brazil). Dept. de Radiologia; Boechat, Lucia de Fatima; Quaresma, Patricia Souto Maior [Universidade Federal, Rio de Janeiro, RJ (Brazil). Hospital Universitario Clementino Fraga Filho. Servico de Radiodiagnostico

    1995-09-01

    The radiological findings of 189 cases of Kaposi`s sarcoma occurring in patients with AIDS were studied. There was also made pathological correlations in these patients. Interstitial reticular infiltrations were frequently detected on thoracic examination showing paracardiac confluent areas. There was also lymphadenopathy, gross nodules and pleural fluid accumulation. Although there was no detection of any pathognomonic aspect, the interstitial reticular infiltration finding together with the paracardiac confluent areas and associated with gross nodules, is highly indicative to thoracic involvement by the disease. (author). 32 refs., 5 figs., 2 tabs.

  3. MR imaging in the diagnosis of the os trigonum syndrome; Il ruolo della Risonanza Magnetica nella diagnosi della sindrome dell'os trigonum

    Energy Technology Data Exchange (ETDEWEB)

    Tamburrini, O.; Porpiglia, H.; Barresi, D.; Bertucci, B.; Console, D. [Catanzaro Univ. Magna Grecia, Catanzaro (Italy). Radiologia, Dipt. di Medicina Sperimentale e Clinica

    1999-12-01

    RM nell'ambito delle malattie dolorose del retropiede e piu' in particolare nella sindrome dell'os trigonum, in considerazione della notevole difficolta' clinica per la corretta diagnosi. Lo studio e' stato condotto su sette pazienti che lamentavano dolore al retropiede da piu' di quattro mesi (maschi/femmine=1/6), con eta' compresa tra 16 e 22 anni (eta' media 18,6 anni); 3/7 praticavano attivita' agonistica sportiva, 4/7 danza classica. In 2/7 pazienti l'os trigonum presentava margini irregolari con sclerosi subcondrale e ampliamento della sincondrosi. In 3/7 pazienti e' stata documentata tenosinovite del tendine flessore lungo dell'alluce causata verosimilmente dalla sua compressione e spostamento all'interno della propria guaina, senza ne' alterazione dell'intensita' di segnale dell'os trigonum, ne' ampliamento della sincondrosi. In 1/7 pazienti sono stati rilevati ipertrofia dell'os trigonum, modico ampliamento della sincondrosi e segni importanti di edema midollare nell'os trigonum e nel processo posteriore dell'astragalo. In 1/7 pazienti, pur in presenza di os trigonum rilevato all'esame radiologico tradizionale, l'esame RM non ha documentato alcuno dei segni da riferire a sindrome dell'os trigonum: la diagnosi definitiva e' stata tendinite achillea. La RM e' l'unica metodica che fornisce importanti informazioni sul coinvolgimento dei tessuti molli, della superficie condro-ossea e sulle reazioni sinoviali riuscendo percio' a dimostrare chiaramente l'eventuale coesistente tenosinovite del tendine flessore lungo dell'alluce ed inoltre provvedendo a fornire informazioni dettagliate per il corretto approccio terapeutico. In conclusione, nell'ambito delle malattie dolorose del retropiede da cause ossee, laddove si sospetti clinicamente la sindrome dell'os trigonum, la non invasivita' della RM

  4. Ogilvie's syndrome (acute colonic pseudo-obstruction): review of the literature and report of 6 additional cases; Sindrome di Ogilvie (pseudo-ostruzione della letteratura acuta del colon): revisione della letteratura e descrizione di 6 nuovi casi

    Energy Technology Data Exchange (ETDEWEB)

    Grassi, Roberto; Cappabianca, Salvatore; Porto, Annamaria; Montemarano, Emilio; De Rosa, Roberto [Napoli Univ., Napoli (Italy). Dipartimento medico-chirurgico di internistica clinica e sperimentale, Sezione scientifica di radiodiagnostica, radioterapia e medicina nucleare; Sacco, Maurizio; Quantarelli, Mario [Ospedale San Gennaro, Napoli (Italy). Servisio di radiodiagnostica; Di Mizio, Roberto [Ospedale S. Massimo, Penne (Italy). Servizio di radiologia

    2005-04-01

    Purpose: Ogilvie's syndrome is defined as an acute pseudo-obstruction of the colon, characterized by the signs, symptoms and radiological pattern of a large-bowel obstruction, but without a detectable organic cause. The aetiology of Ogilvie's syndrome appears to be multifactorial, with a series of possibly interacting pathogenic noxae all resulting in colon inactivity. Our study reports on six cases of Ogilvie's syndrome diagnosed and treated between 1997 and 2002. Materials and methods: From October 1997 to September 2002 we studied six patients affected by pseudo-obstruction of the colon. The pseudo-obstruction was recurrent in two cases. Acute dilatation of the colon without radiologically-detectable organic obstruction was the inclusion criterion for the study. Results: Plain abdominal radiography revealed colon dilatation that extended to the splenic flexure in three patients, to the hepatic flexure in two patients, and confined to the transverse colon in one patient. None of the patients showed air-fluid levels of the small intestine. Conclusion: The most relevant clinical finding in Ogilvie's syndrome is abdominal distension, which arises suddenly, has a progressive course and reaches massive levels. The first-line diagnostic investigation is plain abdominal radiography which shows extreme colon dilatation without air-fluid levels of the small intestine. In three of our patients, conservative therapy alone was able to restore normal conditions within five days; two patients required decompressive colonoscopy, and one patient died from cardio-circulatory arrest after 48 hours. [Italian] Scopo: La sindrome di Ogilvie � definita come una pseudo-ostruzione acuta del colon, con i segni, i sintomi e l'aspetto radiologico di un'occlusione del grosso intestino senza una causa organica riconoscibile. L'eziologia della sindrome di Ogilvie appare multifattoriale, come se l'inerzia del colon fosse la via finale comune verso la

  5. Auto immunity in the Ovarian Resistance Syndrome: research and methodology development; Autoinmunidad en el Sindrome de Resistencia Ovarica: investigacion y desarrollo de metodologia

    Energy Technology Data Exchange (ETDEWEB)

    Oliver, P; Balter, H; Robles, A

    1998-07-01

    The project evaluates, it selects it develops, it optimizes and been worth, analytic methods for the detection and quantification of antibodies antireceptor of FSH, decisive of precocious ovarian flaw for insensibility gonadal: Syndrome of Ovarian Resistance (SRO). The study method involves the competitive inhibition of the union marked FSH with Iodine-125 of membrane receiver. The investigations include the following components of the analysis system: to) membrane Receivers, b) Radiotracers, c) negative and positive control Serums, d) Buffers. The constants of likeness and numbers of receivers are evaluated in the material biological employee by means of graphics of Scatchard. Ace for the control of quality, the study of the maximum capacity of union was selected of the ligature to the receiver, like one of the parameters that bigger information toasts on the performance of the same one. The clinical validation was made by means of the use of isolated immuno-globulines starting from the serum of healthy donors considered as negative power stations and of women with SRO confirmed by studies made in the exterior considered as central positive. All this, provides the development of a sensitive and specific reliable qualitative method for the determination of antibodies antireceptor of FSH of immediate application in the area of the human health in our means. [Spanish] El proyecto evalua, selecciona, desarrolla, optimiza y valida, metodos analiticos para la deteccion y cuantificacion de anticuerpos antireceptor de FSH, determinantes de falla ovarica precoz por insensibilidad gonadal: Sindrome de Resistencia Ovarica (SRO). El metodo de estudio involucra la inhibicion competitiva de la union hFSH marcada con Iodo-125 de receptor de membrana. Las investigaciones incluyen los siguientes componentes del sistema de analisis: a) Receptores de membrana, b) Radiotrazadores, c) Sueros de control negativos y positivos, d) Buffers. Se evaluan las constantes de afinidad y numeros

  6. Sindrome "cabeça de pássaro" de Seckel: estudo pneumencefalografico e hormonal de um caso

    Directory of Open Access Journals (Sweden)

    Israel Salmen Schulz

    1975-09-01

    Full Text Available Relato de um caso de síndrome de Seckel apresentando resultados pneumencefalográficos e hormonais dignos de registro. As dosagens hormonais indicaram a existência de um distúrbio na atividade do hormônio de crescimento, havendo estímulo acima do normal do H.G.H. e inatividade sobre a curva dos ácidos graxos não saturados. O registro pneumencefalográfico de atrofia das circunvoluções cerebrais é o primeiro a ser publicado em paciente com síndrome de Seckel, podendo ser considerado como uma confirmação dos achados anátomo-patológicos relatados por McKusick (mierocefalia pongidea.

  7. Sindrome do encarceramento (locked-in syndrome): registro de um caso e revisão de literatura

    OpenAIRE

    Miguel Farage Filho; Mauro de Paiva Gomes

    1982-01-01

    É relatado um caso de síndrome do encarceramento (locked-in-syndrome) em paciente que apresentou quadro súbito de tetraplegia, anartria, movimentos oculares verticais e piscar além de preservação do nível de consciência. Explicação para tal quadro clínico é uma lesão na ponte junto ou sobre o núcleo do nervo abducente seccionando os tratos córtico-espinhal e córtico-bulbar, sem atingir a substância reticular do mesencéfalo. Três EEG revelaram distúrbio projetado por provável lesão do tronco c...

  8. Analise do movimento de arremessar em diferentes tarefas realizadas por crianças portadoras de Sindrome de Down

    OpenAIRE

    Marli Nabeiro

    1993-01-01

    Resumo: Este estudo teve por objetivo investigar o comportamento motor, através do arremesso por cima, de crianças portadoras de Síndrome de Down, com deficiência mental em nível moderado. Tal situação visa verificar o nível de desenvolvimento e a influência do ambiente sobre o comportamento motor. Participaram do estudo 27 crianças portadoras de Síndrome de Down, com idade entre 8 e 12 anos, alunos do Setor Educacional do Centro de Habilitação da APAE, que foram filmadas na execução do movim...

  9. Sindrome do encarceramento (locked-in syndrome: registro de um caso e revisão de literatura

    Directory of Open Access Journals (Sweden)

    Miguel Farage Filho

    1982-09-01

    Full Text Available É relatado um caso de síndrome do encarceramento (locked-in-syndrome em paciente que apresentou quadro súbito de tetraplegia, anartria, movimentos oculares verticais e piscar além de preservação do nível de consciência. Explicação para tal quadro clínico é uma lesão na ponte junto ou sobre o núcleo do nervo abducente seccionando os tratos córtico-espinhal e córtico-bulbar, sem atingir a substância reticular do mesencéfalo. Três EEG revelaram distúrbio projetado por provável lesão do tronco cerebral, e que foi confirmada pelo CAT SCAN. Arteriografia vertebral mostrou grau avançado de aterosclerose. Com tratamento clínico conservador o paciente teve ótima evolução.

  10. Profilaxia da anemia ancilostomótica: sindrome de carencia Prophylaxis of Hookworm Anemia-carencial syndrome

    Directory of Open Access Journals (Sweden)

    W. O. Cruz

    1945-04-01

    Full Text Available É apresentada uma revisão das recentes aquisições na anemia ancilostomótica, assinalando a importância de alimentação qualitativamente deficiente junto á infestação helmíntica na gênese desta doença. Acentuou-se que a anemia ancilostomótica é uma doença de carência. Profilaxia clássica da Ancilostomose resume-se em evitar a infestação do homem pelos ancilostomídeos. Critica-se a aplicabilidade destas medidas e eficiência das mesmas no que diz respeito á incidência da anemia. O presente trabalho mostra aquisições preliminares sôbre fundamentos de uma profilaxia de carência (tipo profilaxia do bócio endêmico da anemia ancilostomótica, baseada na administração de alimentos contaminados por um sal de ferro. As misturas sulfato ferroso-farinha de mandióca e citrato férrico amoniacal-caldo de feijão, mostraram-se eficientes em prevenir a queda das cifras hemáticas durante largos períodos de tempo em indivíduos maciçamente infestados (6-8 meses. Não foi verificada a dose diária mínima eficiente dêstes sais, obtendo-se resultados satisfatorios mesmo com 0.1 g diária de sulfato ferroso (correspondendo a 0.037 g de ferro metálico. Numerosos alimentos e sais de ferro foram experimentados com resultados infrutíferos por diferentes razões. A influência dos helmintos, pela hemorragias intestinais que acarretam poude ser mais uma vez estudada, nos casos de sais de ferro administrados em doses ineficientes ou em períodos de prova sem medicação marcial. É proposta nova classificação de intensidade de infestação, levando em consideração o conhecido fato de ser a atividade dos helmintos, exclusivamente expoliadora. Em conclusão, nos parece exequível a profilaxia da anemia ancilostomótica mediante ingestão de alimentos contaminados por quantidades eficientes de sais de ferro. Êste método profilático extremamente econômico será na prática, provàvelmente, muito superior aos métodos de profilaxia

  11. Down Syndrome = Sindrome de Down.

    Science.gov (United States)

    Pueschel, S. M.; Glasgow, R. E.

    Presented both in English and Spanish, the brochure is primarily concerned with biological and developmental characteristics of the person with Down's syndrome. An emphasis is on the valuable humanizing influence these individuals have on society. Brief sections in the document discuss the delayed developmental aspects of Down's syndrome; the…

  12. Sindrom pomagača” kod djelatnika koji rade s osobama s oštećenjima vida

    OpenAIRE

    Fulgosi-Masnjak, Rea; Vidmar, Margareta; Masnjak, Mia

    2008-01-01

    Ovo istraživanje provedeno na djelatnicima koji su zaposleni u neposrednom radu s osobama s oštecenjima vida razlicitog uzrasta prvo je u nas. Cilj istraživanja bio je odrediti stupanj izraženosti sindroma pomagaca ("Helper sindroma") u odnosu na neke kriterijske varijable. "Pomagači" su obicno oni strucnjaci koji pružaju pomoc osobama u potrebi, cesto u emocionalno stresnim okolnostima koje utjecu na njihovo mentalno zdravlje. Oni najcešce ispoljavaju altruisticnu, nematerijalisticku i hu...

  13. Uso de fármacos na síndrome de hiperatividade com déficit de atenção Use of drugs in attention deficit hyperactivity disorder

    Directory of Open Access Journals (Sweden)

    Ana Guardiola

    1997-09-01

    Full Text Available A sindrome de hiperatividade com déficit de atenção (SHDA constitui distúrbio comum na infância, podendo advir de fatores exógenos ou endógenos, os quais são responsáveis por comprometimento cerebral, manifestando-se por alterações funcionais dos sistemas motores, perceptivos, cognitivos e do comportamento, comprometendo a aprendizagem de crianças com potencial intelectual adequado. Os autores estudam a ação de fármacos estimulantes e antidepressivos na SHDA, usando como parâmetro de eficácia as provas de persistência motora.Attention deficit hyperactivity disorder (ADHD is a neurological disorder which is common in the childhood and can be caused by exogenous and endogenous factors, that are responsible for cerebral disorder. This disorder presents a functional alteration of the motor, perceptive, cognition systems and conduct disorders compromising the learning of children with an adequate intellectual potential. The authors study the action of stimulants and antidepressive drugs in the ADHD, using as measure of efficacy the motor persistence tests.

  14. Pneumocystis carinii pneumonia in acquired immunodeficiency syndrome - correlation of high-resolution computed tomography and anatomopathology; Pneumocistose na sindrome da imunodeficiencia adquirida: correlacao da tomografia computadorizada de alta resolucao com a anatomopatologia

    Energy Technology Data Exchange (ETDEWEB)

    Marchiori, Edson; Moreira, Luiza Beatriz [Universidade Federal Fluminense, Niteroi, RJ (Brazil). Dept. de Radiologia]. E-mail: edmarchiori@zipmail.com.br; Capone, Domenico [Universidade do Estado, Rio de Janeiro, RJ (Brazil). Faculdade de Medicina; Moraes, Heleno Pinto de [Universidade Federal Fluminense, Niteroi, RJ (Brazil). Dept. de Patologia; Pereira, Cyntia Inez Guedes Soares

    2001-12-01

    We present the main findings observed on the high-resolution computed tomography examinations of 15 patients with acquired immunodeficiency syndrome and Pneumocystis carinii pneumonia. The high-resolution computed tomography and autopsy findings of 5 patients were also compared. The most frequently observed high-resolution computed tomography patterns were ground-glass attenuation, consolidation areas, crazy-paving pattern and cysts. Nodules and intralobular reticulation were less frequently observed. Ground-glass attenuation and consolidation areas corresponded to alveolar filling with inflammatory exudate. Thickening of the interlobular septa was due to cell infiltration and edema. One patient presented interlobular reticulation, and the pathology study revealed alveolar septa thickening due to cell infiltration and fibrosis. Nodules observed in one of the patients corresponded to a patchy intra alveolar accumulation of microorganisms and inflammatory cells forming a 'granulomatous' pattern. (author)

  15. Sindrome de Van der Knaap megalencefalia com leucodistrofia: a respeito de dois casos na mesma família Van Der Knaap syndrome (megalencephaly with leukodystrophy: report of two cases in the same family

    Directory of Open Access Journals (Sweden)

    CARLOS EDUARDO CAVALCANTI

    2000-03-01

    Full Text Available Relatamos os casos de dois irmãos, com quatro e seis anos de idade, com achados característicos da síndrome de Van Der Knaap. Discutimos os seus aspectos clínicos e radiológicos, assim como suas peculiaridades. Comparamos aos dados da literatura e analisamos os possíveis mecanismos etiopatogênicos envolvidos.We report on two brothers, aged four and six years-old, evidencing the Van Der Knaap syndrome. Clinical and radiological aspects are discussed as well their peculiarities. Data are compared with related literature, as etiopathogenic mechanisms possibly involved.

  16. Načrtovan porod na domu

    OpenAIRE

    Todorović, Tamara; Takač, Iztok

    2017-01-01

    Izhodišča: Porod na domu je sicer star toliko kot človeštvo, pa vendar v veliki večini srednje in visoko razvitih držav prevladuje mnenje, da so zaradi nepredvidljivosti zapletov porodnišnice najbolj varno okolje za rojevanje. Kljub temu obstaja peščica držav, v katerih je porod na domu integriran v sistem zdravstvenega varstva (npr. Nizozemska, Velika Britanija, Kanada). Pri porodih na domu ločimo nenačrtovane in načrtovane porode na domu, slednje pa lahko nadalje razdelimo še na porode s sp...

  17. Doença oclusiva progressiva das artérias cerebrais associada a sindrome de Down: registro de um caso

    Directory of Open Access Journals (Sweden)

    Israel Salmen Schulz

    1980-06-01

    Full Text Available Registro de um caso que pode ser o segundo na literatura mundial de associação de "moyamoya" com síndrome de Down, caracterizando-se pela permeabilidade das artérias carótidas internas, cerebrais médias e anteriores. O comprometimento da circulação distai poderia levantar a possibilidade de uma alteração da microcirculação capilar e, inclusive, da ação de alguma substância não determinada, fatores que poderiam explicar a localização e bilateralidade das lesões.

  18. Sindrome de Guillain-Barré como manifestação do lupus eritematoso sistêmico: registro de um caso

    Directory of Open Access Journals (Sweden)

    Pedro F. Moreira Filho

    1980-06-01

    Full Text Available É relatado caso de paciente jovem do sexo feminino que apresentou, de modo agudo, quadro de polirradiculoneurite com acometimento de vários nervos cranianos e dissociação albumino-citológica no líquido cefalorraqueano. Os exames complementares mostraram tratar-se de lupus eritematoso sistêmico. A biópsia de nervo periférico revelou diminuição de fibras mielínicas, fibrose do endo e perineuro e hipertrofia da camada média dos vasa-nervorum. Os autores chamam a atenção para a raridade do acometimento do sistema nervoso periférico na vigência da doença lúpica. Acreditam que a síndrome de Guillain-Barré provocada pelo lupus eritematoso sistêmico seria devido a um mecanismo imuno-alérgico.

  19. Síndrome do ceco móvel e as doenças gastrintestinais funcionais Mobile cecum sindrome and the functional gastrointestinal illnesses

    Directory of Open Access Journals (Sweden)

    Júlio César Monteiro dos Santos Jr.

    2006-12-01

    Full Text Available O ceco móvel é uma variação anatômica embriológica do ceco e cólon ascendente resultante da descida incompleta desses segmentos do intestino grosso e da não fixação no peritônio da goteira parieto-cólica direita. A falta dessa fusão permite movimentação do ceco e/ou do cólon ascendente, facilitando a torção sobre seu eixo longitudinal ou a dobra medial do ceco sobre si, ficando encostado com sua borda medial à borda medial do cólon ascendente. Esse fato causa sintomas intermitentes de obstrução parcial do intestino ou, no caso de torção completa (volvo, de obstrução aguda com possível necrose do segmento envolvido. A anormalidade embriológica tem alta incidência (10 a 30% na população, contudo só tem sido mencionada por ocasião da torção completa, inadequadamente denominada de volvo do ceco-ascendente, em geral com necrose cecal. Dessa forma, a ocorrência não é das mais comuns e está citada entre as causas de obstrução intestinal aguda, perfazendo, nos adultos e nas crianças, menos do que 2% de todos os casos de obstruções intestinais, mas com a importância de destaque por causa do alto índice de morbi-mortalidade entre os pacientes afetados. O objetivo foi apresentar o ceco móvel como causa de dor abdominal intermitente, distensão, empachamento e cólica de origens obscuras em pessoas de aparência saudável, mas com uma longa história de distúrbios gastrintestinais funcionais, associados à constipação e/ou diarréia, portanto, com um quadro sintomatológico sobreponível ao da síndrome do cólon irritável. Além disso, propomos um marcador anatômico para a síndrome do cólon irritável, seja o subtipo com constipação predominante, seja o da diarréia predominante ou a forma em que há alternância entre constipação e diarréia e a possibilidade de alívio daqueles sintomas com a cecopexia.Functional gastrointestinal (FGI disorders are chronic or periodic conditions characterized by

  20. Parametri za procena na kvalitetot na polietilenska i na polipropilenska ambalaza i na gumeni zatvoraci nameneti za farmacevtski preparati

    Directory of Open Access Journals (Sweden)

    Liljana Ugrinova

    2002-03-01

    Full Text Available Napraven e pregled na parametrite za procena na kvalitetot na polietilenska i na polipropilenska ambalaza i na gumeni zatvoraci nameneti za farmacevtski preparati. Za procena na kvalitetot na ispituvaniot materijal bea izvrseni fizicki, hemiski i bioloski ispituvanja spored postapkite dadeni vo Ph. Eur., DIN i spored DIN ISO standardite. Baranjata za kvalitet na ovoj vid ambalaza propisani spored Ph. Eur., DIN i DIN ISO standardite se razlikuvaat vo odnos na predvidenite parametri za fizicki, za hemiski i za bioloski ispituvanja. Isto taka, propisani se i razlicni granici na dozvoleno otstapuvanje na oddelni parametri.

  1. Sindrome de regresión caudal

    OpenAIRE

    Maldonado, A.; Pastor, A.; Sorni, A.; Pastor Durán, Xavier; Palomeque,A.

    1995-01-01

    El síndrome de regresión caudal o de agenesia sacra se caracteriza por un déficit funcional de los esfínteres y de la muscultatura de los miembros inferiores. Se suele asociar con otras malformaciones, como son las esqueléticas, genitourinarias y del tracto intestinal. La diabetes mellitus materna es uno de los factores predisponentes más destacados. Aquí se presenta un caso de síndrome de regresión caudal con insufiencia renal secundaria a la uropatía malformativa asociada. Se comentan los d...

  2. Graves Disease And Down Sindrome : Clinical Case

    Directory of Open Access Journals (Sweden)

    Scrinic Olesea

    2015-08-01

    Full Text Available Introduction: Pacients with Down’s syndrome present an increase revalence of autoimune endocrine disorders. We communicate the case of 14 years and 6 months old pacient known with Down syndrome admitted in Endocrinology department with suspicion of hyperthyroidism, the diagnosis being confirmed by hormonal dosage. The particularity of the case consists in: symptomatology onset during puberty, clinical evolution with mild symptoms, without ocular involvement, morphological and functional remission obtained relatively soon after the initiation of antithyroid therapy, lack of posttherapy side effects, favorabile evolution under the “block and replace” therapy

  3. EL SINDROME VESTIBULAR EN EL ADULTO MAYOR

    Directory of Open Access Journals (Sweden)

    Dr. Hamlet Suárez

    2016-11-01

    Full Text Available El vértigo, la inestabilidad y las caídas tienen una incidencia relevante en el adulto mayor, disminuye su calidad de vida y puede ser causa de muerte en esta población. Este artículo describe las presentaciones clínicas y el abordaje de la evaluación de la patología vestibular en este grupo de edad, utilizando diferentes instrumentos para el diagnóstico así como también las reglas generales del tratamiento.

  4. SINDROME DE COLAPSO DE MORDIDA POSTERIOR

    Directory of Open Access Journals (Sweden)

    Paula Alejandra Baldión

    2012-07-01

    El objetivo del artículo es describir la manera como evoluciona la enfermedad, la evaluación multidisciplinaria para obtener un diagnóstico preciso y la secuencia de tratamiento integral, revisando los conceptos para un mejor entendimiento del tratamiento periodontal y restaurativo que requieren los pacientes con síndrome de colapso de mordida posterior; caracterizado por procesos patológicos como enfermedad periodontal, caries dental con subsecuente alteración de la integridad del arco dentario que genera perdida de soporte posterior conllevando a un trauma oclusal secundario y disminución de la dimensión vertical oclusal. El control del proceso inflamatorio y la estabilización periodontal son puntos de partida indispensables en el tratamiento integral del paciente. La migración patológica de los dientes y las alteraciones del plano oclusal pueden exigir la corrección ortodóntica de los arcos y en algunos casos el concurso de cirugía oral para la nivelación del plano oclusal. La secuencia organizada del tratamiento por fases permite la restauración predecible de los pacientes con este síndrome, tomando en cuenta las diferentes alternativas protésicas tanto removibles como fijas con o sin implantes de oseointegración, para el éxito integral a largo plazo.

  5. Churg Strauss syndrome; Sindrome de Churg Strauss

    Energy Technology Data Exchange (ETDEWEB)

    Lopez Rengifo, Diana Milena; Contreras Zuniga, Eduardo; Osio, Luis Fernando

    2007-07-01

    The Churg-Strauss syndrome, also called allergic granulomatosis and angiitis, is a multisystem disorder characterized by allergic rhinitis, asthma, and prominent peripheral blood eosinophilia. The most common organ involved is the lung, followed by the skin. The Churg-Strauss syndrome, however, can affect any organ system, including the cardiovascular, gastrointestinal, renal, and central nervous systems.

  6. SINDROME DE COLAPSO DE MORDIDA POSTERIOR

    Directory of Open Access Journals (Sweden)

    Paula Alejandra Baldión

    2012-12-01

    Full Text Available El Síndrome de Colapso de Mordida posterior es una patología oclusal que se presenta como consecuencia de problemas dentales, periodontales y oclusales, que exige la correcta evaluación de los signos y síntomas que lo caracterizan.  El objetivo del artículo es describir la manera como evoluciona la enfermedad, la evaluación multidisciplinaria para obtener un diagnóstico preciso y la secuencia de tratamiento integral, revisando los conceptos para un mejor entendimiento del tratamiento periodontal y restaurativo que requieren los pacientes con síndrome de colapso de mordida posterior; caracterizado por procesos patológicos como enfermedad periodontal, caries dental con subsecuente alteración de la integridad del arco dentario que genera perdida de soporte posterior conllevando a un trauma oclusal secundario y disminución de la dimensión vertical oclusal. El control del proceso inflamatorio y la estabilización periodontal son puntos de partida indispensables en el tratamiento integral del paciente. La migración patológica de los dientes y las alteraciones del plano oclusal pueden exigir la corrección ortodóntica de los arcos y en algunos casos el concurso de cirugía oral para la nivelación del plano oclusal. La secuencia organizada del tratamiento por fases permite la restauración predecible de los pacientes con este síndrome, tomando en cuenta las diferentes alternativas protésicas tanto removibles como fijas con o sin implantes de oseointegración, para el éxito integral a largo plazo.

  7. Sindromes Dolorosos Regionales, Columna, Hombro y Rodilla

    Directory of Open Access Journals (Sweden)

    Wolff C. Verónica, Dra.

    2012-07-01

    En la rodilla, los trastornos periarticulares incluyen bursitis y tendinitis de distintas estructuras, y hay que considerar la osteonecrosis dentro del diagnóstico diferencial del dolor de rodilla del adulto mayor.

  8. Congenital Primary Pachydermoperiostosis and Striate Palmoplantar Keratoderma - a Case Report

    OpenAIRE

    Stojanović Slobodan; Vučković Nada; Jovanović Marina; Petrović Kosta

    2014-01-01

    Uvod. Pahidermoperiostoza (PDP) predstavlja heterogeni sindrom za koji su karakteristične hipertrofi čne promene prvenstveno kože i kostiju ekstremiteta: pahidermija, klabing (clubbing) prstiju šaka i stopala i hipertrofi čna osteoartropatija. Primarna pahidermoperiostoza − sinonim Turen−Solent−Goleov sindrom (Touraine-Solente-Golé) (PPDP), ili primarna hipertrofi čna osteoartropatija (PHO), redak je nasledni poremećaj i predstavlja jedan od dva tipa hipertrofi čne osteoartropatije....

  9. At NA2

    CERN Multimedia

    1977-01-01

    One of the NA2 calorimeter sections is moved in. The NA2 calorimeter was divided in two halves, to the left and the right of the beam, each half consisting of sheets of passive high Z material interleaved with blades of plastic scintillators. The photo shows on the right, the upstream 'electron' module with eleven lead plates for a total radiation length of 20.

  10. Polarization dependence of Na* + Na* associative ionization revisited

    NARCIS (Netherlands)

    Meijer, H.A.J.; Meulen, H.P. v.d.; Morgenstern, R.; Hertel, I.V.; Meyer, E.; Witte, R.

    1986-01-01

    The dependence of the associative ionization process Na 3 2P3/2 + Na 3 2P3/2 → Na2+ + e- on the polarization of the laser light used for Na excitation was independently investigated in Utrecht and Berlin. The purpose of this paper is to clarify discrepancies between two other earlier experimental

  11. NAKUPOVANJE NA SPLETU

    OpenAIRE

    Visenjak, Monika

    2013-01-01

    Nakupovanje na spletu je prihodnost poslovanja. Za podjetja pomeni manjše stroške, lažje prilagajanje tržnim pogojem. Hitreje lahko razvijajo odnose in analizirajo uporabnike, saj jim je dan dostop o nakupnih podatkih uporabnika. Za potrošnike je nakupovanje na spletu možnost hitrega, preprostega in učinkovitega nakupovanja od doma ali pisarne. Pomembno je, da se seznanijo z vsemi informacijami in pogoji spletnih trgovin, saj se lahko le tako izognejo nezadovoljstvu ob nakupu v spletni trgovi...

  12. Sindromes endocrinos autoinmunes: cuándo sospechar y estudiar un sindrome poliglandular (SPG)

    OpenAIRE

    B. María Carolina Letelier, Dra.

    2013-01-01

    Los síndromes poliglandulares autoinmunes comprenden un amplio espectro de trastornos endocrinos. Estos síndromes incluyen trastornos monogénicos como el síndrome poliglandular tipo 1 (tipo juvenil) y trastornos genéticos complejos como el síndrome poliglandular tipo 2 (tipo adulto). Estos trastornos se basan en la presencia de infiltración linfocitaria de la glándula afectada, anticuerpos órgano-específico en sangre, defectos en la inmunidad celular y asociación con los genes de los antígeno...

  13. Riso na epilepsia

    Directory of Open Access Journals (Sweden)

    Edymar Jardim

    1967-06-01

    Full Text Available São estudados três casos de síndrome convulsiva temporal, com manifestações concomitantes de riso na sua fase inicial. As características principais foram a imotivação e á incoercibilidade do riso. Esses sintomas desapareceram com o uso de anticonvulsivantes.

  14. Atletismo na escola : realidade?

    OpenAIRE

    Sampaio, Alessandro Oliveira de

    2012-01-01

    O correr, saltar, lançar e arremessar são elementos básicos do atletismo, sendo fundamentais para o ser humano, devido ao favorecimento do desenvolvimento físico e motor. Sendo um dos conteúdos principais do desporto e da educação física escolar, foi realizado um estudo relacionado à prática do atletismo na escola, na qual o objetivo desta pesquisa foi verificar se entre os professores de educação física da rede pública de ensino fundamental de 5ª a 8ª séries, da cidade satélite de Samambaia ...

  15. Preparing for NA4

    CERN Multimedia

    CERN PhotoLab

    1977-01-01

    Here, in one of the EF workshop, Albert Duchêne works on a pretty piece of mechanics. A few others await to be attended on the left. There are indications that the pipes were meant to house the carbon target (subdivided in eight sections) to be installed inside the toroid magnet of the NA4 experiment. The external strips were designed to possibly correct the magnetic field (???).

  16. The CERES / NA45 experiment

    CERN Multimedia

    Laurent Guiraud

    2000-01-01

    Ceres is one of the second generation heavy ion experiments at CERN's SPS. It is dedicated to the study of electron-positron pairs in relativistic nuclear collisions. NA45 is one of the seven experiments (NA44, NA45, NA49, NA50, NA52, WA97/NA57 and WA98) involved in CERN's Heavy Ion programme which provided evidence for the existence of a new state of matter, the quark-gluon plasma. In this state, quarks, instead of being bound up into more complex particles such as protons and neutrons, are liberated and roam freely. Theory predicts that this state must have existed at about 10 microseconds after the Big Bang, before the formation of matter as we know it today.

  17. Envolvimento pulmonar na polimiosite

    Directory of Open Access Journals (Sweden)

    Direndra Hasmucrai

    2010-07-01

    Full Text Available Resumo: Introdução: A polimiosite (PM e a dermatomiosite são classificadas como miopatias inflamatórias idiopáticas. O envolvimento pulmonar por PM é pouco frequente, estando descrito na literatura em cerca de 10% de casos.Os autores apresentam um caso de uma mulher de 75 anos, com queixas de febre, perda ponderal, artralgias, mialgias e diminuição simétrica e proximal da força muscular com impotência funcional dos membros superiores e inferiores, com início um mês antes do internamento. Apresentava infiltrados pulmonares na telerradiografia de tórax. Após estudo exaustivo estabeleceu-se o diagnóstico de envolvimento pulmonar na forma de pneumonia organizativa por PM. Efectuou-se corticoterapia e terapêutica com micofenolato com melhoria clínica, analítica e radiológica. Conclusão: Neste caso, foi a alteração na telerradiografia de tórax numa doente sem sintomatologia respiratória que levou ao estudo exaustivo até ao diagnóstico de PM, realçando mais uma vez a importância da telerradiografia no rastreio de patologias de outros foros. Abstract: Introduction: Polymyositis and dermatomyositis are classified as idiopathic inflammatory myopathies. Interstitial lung disease is rare and is described in the literature in about 10% of cases.The authors describes a case of 75 year old woman presenting with one month evolution of fever, weight loss, arthralgia, myalgia and symmetric and proximal muscle weakness of upper and lower limbs. Nonspecific interstitial changes was found in chest X-ray. After exhaustive study, the diagnosis of pulmonary envolvement in the form of organizing pneumonia by polymyositis, was established. Glucocorticoids and mycophenolate were prescribed with good clinical, analytical and radiological outcome. Conclusion: In this case, it was the changes in the chest X-ray in a patient without respiratory symptomatology, that conducted to exhaustive study to polymyositis diagnosis, enhancing once again the

  18. Comprometimento pulmonar na leptospirose

    Directory of Open Access Journals (Sweden)

    Jorge Eduardo Manhães de Carvalho

    1992-03-01

    Full Text Available Em 23 pacientes com leptospirose apresentando comprometimento pulmonar, internados no Hospital Universitário Antônio Pedro da XJFF, Niterói, hemoptise e hemoptóicos foram observados em 21,7% e 30,4%, respectivajnente. Gasometria arterial revelou hipoxemia e hipocapnia na maioria dos casos. Radiografia de tórax em 15 pacientes mostrou comprometimento alveolar em 60%, comprometimento intersticial-reticular em 6%, padrão misto (alveolar e intersticial em20%e ausência de alterações radiológicas em 14%. A necrópsiade 13 pacientes mostrou edema, congestão e hemorragia nos pulmões em 100% dos casos. A hemorragia foi focal em 46% e difusa em 54% dos casos. Houve formação de membrana hialina em 30% e trombos de fibrina em 46% dos pulmões estudados, o que estabelece o diagnóstico da coagulação intravascular disseminada e a ocorrência da síndrome de angústia respiratória na leptospirose.

  19. Measurement of exchangeable sodium: 22Na or 24Na

    International Nuclear Information System (INIS)

    Smith, T.; Edmonds, C.J.

    1987-01-01

    A case is made for the use of 22 Na in low activities in preference to 24 Na for routine diagnostic estimation of exchangeable sodium, and is based chiefly on considerations of availability, cost and radiation dosimetry. A method in which only 37 kBq (1 μCi) 22 Na is administered orally is shown to be sufficiently accurate and to possess distinct advantages in terms of cost and convenience with a committed radiation dose no greater than that for a measurement using 24 Na. (author)

  20. The NA27 trigger

    International Nuclear Information System (INIS)

    Bizzarri, R.; Di Capua, E.; Falciano, S.; Iori, M.; Marel, G.; Piredda, G.; Zanello, L.; Haupt, L.; Hellman, S.; Holmgren, S.O.; Johansson, K.E.

    1985-05-01

    We have designed and implemented a minimum bias trigger together with a fiducial volume trigger for the experiment NA27, performed at the CERN SPS. A total of more than 3 million bubble chamber pictures have been taken with a triggered cross section smaller than 75% of the total inelastic cross section. Events containing charm particles were triggered with an efficiency of 98 +2 sub(-3)%. With the fiducial volume trigger, the probability for a picture to contain an interaction in the visible hydrogen increased from 47.3% to 59.5%, reducing film cost and processing effort with about 20%. The improvement in data taking rate is shown to be negligible. (author)

  1. Na Cauda do Cometa

    Science.gov (United States)

    Voelzke, M. R.

    2009-01-01

    Quando viam um cometa, os antigos gregos imaginavam uma estrela com uma vasta cabeleira. Não à toa, a palavra deriva do termo koma, que significa cabelo. Constituídos por fragmentos de gelo e gases, os cometas possuem um núcleo sólido, que pode ter vários quilômetros de diâmetro, e uma cauda que sempre aponta na direção contrária ao Sol, devido aos ventos solares. Graças à aparência de pontos luminosos em movimento (ao contrário de outros astros, que parecem estáticos), esses corpos celestes foram interpretados por diferentes povos com muito misticismo, inspirando mitos tanto de boas-novas como de maus presságios. Conheça algumas dessas histórias:

  2. NA48 prototype calorimeter

    CERN Multimedia

    1990-01-01

    This is a calorimeter, a detector which measures the energy of particles. When in use, it is filled with liquid krypton at -152°C. Electrons and photons passing through interact with the krypton, creating a shower of charged particles which are collected on the copper ribbons. The ribbons are aligned to an accuracy of a tenth of a millimetre. The folding at each end allows them to be kept absolutely flat. Each shower of particles also creates a signal in scintillating material embedded in the support disks. These flashes of light are transmitted to electronics by the optical fibres along the side of the detector. They give the time at which the interaction occurred. The photo shows the calorimeter at NA48, a CERN experiment which is trying to understand the lack of anti-matter in the Universe today.

  3. A ENGENHARIA NA ESCOLA

    Directory of Open Access Journals (Sweden)

    Valéria Pelizzer Casara

    2015-04-01

    Full Text Available Este projeto teve por objetivo principal mostrar às jovens do ensino médio, como as áreas de exatas e de engenharia podem estar inseridas em situações rotineiras por elas vivenciadas e incentivá-las para ingressarem nessas áreas. O projeto foi executado na escola de ensino Médio Nelson Horostecki na cidade de Chapecó, Santa Catarina. Mostrou-se de forma simples que as áreas de exatas e de engenharia têm aplicações práticas nas nossas vidas. No desenvolvimento do projeto, realizaram-se oficinas na escola cujo tema principal abordado foi o processo de fabricação do chocolate, visto que o mesmo é um produto muito apreciado pelas adolescentes. Dentro dessa temática, foram trabalhadas as questões que envolvem conhecimentos das áreas de exatas e de engenharia, mais especificamente a Engenharia Ambiental. O projeto auxiliou na formação cidadã e também na escolha profissional das meninas. Muitas das alunas participantes nunca haviam tido contato direto com alunos graduandos de cursos na área das exatas. Mais ainda, este projeto oportunizou a aproximação da universidade com a comunidade externa. Palavras-chave: Extensão Universitária, Ciências Exatas e Engenharia, Chocolate, Oficinas.   Engineering in the school Abstract: The main objective of this project was to show high school female students how the exact sciences and engineering can be included in their routine situations encouraging them to entering in these areas. The project was carried out at the Nelson Horostecki High School in Chapecó, Santa Catarina State, Brazil. It was showed in a simple manner how exact sciences and engineering have practical applications in our lives. Workshops were conducted in the school during the execution of the project in which the main subject was the chocolate manufacturing process, since chocolate is a product greatly appreciated by the young female people. Within this matter, the activities were performed using the knowledge of

  4. Investigation on U - O - Na, Pu - O - Na and U,Pu - O - Na phase diagrams

    International Nuclear Information System (INIS)

    Pillon, S.

    1989-03-01

    The thermochemical interaction between the nuclear fuel (uranium and plutonium mixed oxides) and the sodium has been investigated and particularly the three phase diagrams: U - O - Na; Pu - O - Na; U,Pu - O - Na. High temperature neutron diffraction, microcalorimetry and powder X-ray diffraction were used for the characterization of the compounds synthetized. This study allowed to complete the knowledge about each of these diagrams and to measure some physical and thermal properties on the compounds. The limits on the modelization of the fuel-sodium interaction are discussed from the results of the UO 2 - Na reaction [fr

  5. Inclusão de crianças com Síndrome de Down Inclusión de niños con Sindrome de Down Inclusion of children with Down Syndrome

    Directory of Open Access Journals (Sweden)

    Flávia Mendonça Rosa Luiz

    2012-12-01

    Full Text Available O objetivo deste trabalho foi explorar as experiências de famílias no processo de inclusão escolar de crianças com síndrome de Down, com vistas à promoção de saúde dessas famílias. Trata-se de um estudo de casos múltiplos, de abordagem qualitativa, em que participaram onze famílias de crianças com síndrome de Down. Os dados foram coletados por meio de entrevista semiestruturada e submetidos à análise de conteúdo. Os resultados demonstraram que, na perspectiva dos participantes, os professores não estão preparados para a inclusão, porém, ainda assim, esse processo vem se demonstrando benéfico na educação infantil. Ficou evidente a necessidade de articulação entre os setores da educação e saúde e de uma mudança de paradigma no modelo educacional. A pesquisa aponta aspectos que merecem atenção por parte dos profissionais envolvidos, de modo a tornar a inclusão um processo a ser vivido da melhor forma possível.La finalidad fue explorar las experiencias de familias en el proceso de inclusión escolar de niños con síndrome de Down, para promover la salud de esas familias. Se trata de un estudio de casos múltiples, con aproximación cualitativa, en que participaron 11 familias de niños con síndrome de Down. Los datos fueron recolectados mediante entrevista semiestructurada y analizados con análisis de contenido. Los resultados demostraron que, en la perspectiva de los participantes, los profesores no están preparados para la inclusión. Sin embargo, ese proceso viene mostrándose benéfico en la educación infantil. Se quedó evidente la necesidad de articulación entre los sectores de educación y salud y un cambio de paradigma en el modelo educacional. La investigación apunta aspectos que merecen atención de la parte de los profesionales involucrados, de manera a hacer de la inclusión un proceso a ser vivida de la mejor forma posible.This study aimed to explore families' experiences in the educational

  6. O ato de comer e as pessoas com Síndrome de Down El acto de comer y las personas con Sindrome de Down Eating act and people with Down Syndrome

    Directory of Open Access Journals (Sweden)

    Andréa Giaretta

    2009-06-01

    Full Text Available Trata-se do relato de experiência vivida durante a disciplina de Projetos Assistenciais de Enfermagem e de Saúde do Curso de Mestrado em Enfermagem da Universidade Federal de Santa Catarina de cunho interdisciplinar, realizado com pessoas com Síndrome de Down com foco tanto na sua racionalidade quanto no seu imaginário. Buscou-se construir junto com estas pessoas e seus familiares uma sistematização nutricional individualizada que contribuísse para sua independência pessoal na prática cotidiana do ato de comer. Os postulados do Interacionismo Simbólico guiaram esta prática e se interligaram com os instrumentos metodológicos da escuta e da observação sensível, além das atividades lúdicas. Evidenciou-se que o primeiro significado do ato de comer é construído pela sua família e reforçado pelo seu convívio social.Eso es un relato de una experiencia vivida en la disciplina de Proyectos Asistenciales de Enfermaría y de Salud del Curso de Maestría en Enfermaría de la Universidad Federal de Santa Catarina con característica interdisciplinario, hecho con personas con el Síndrome de Down, con la atención tanto para la racionalidad cuanto para el imaginario. Se ha buscado construir juntamente a las personas con el Síndrome de Down y sus familiares una sistematización de nutrición individualizada que contribuyese para su independencia personal en la práctica cotidiana del acto de comer. Los postulados del Interaccionismo Simbólico condujeron la práctica y interconectáronse con los instrumentos metodológicos de la escucha y de la observación sensible, además de las actividades lúdicas. Fue evidenciado que el primer significado del acto de comer es transmitido por sus familias y reforzado por el convivir social.This is en experience report lived in the Health and Nursing Assistance Projects of the Post-Graduate Nursing Master Degree of the Federal University of Santa Catarina as an interdisciplinary subject, and it was

  7. Valores na escola

    Directory of Open Access Journals (Sweden)

    Menin Maria Suzana De Stefano

    2002-01-01

    Full Text Available Neste texto pretende-se discorrer sobre valores morais na escola e suas implicações para a formação de professores. Para tanto discutir-se-á, em primeiro lugar, e brevemente, o que são valores morais, ou éticos, e como a escola pode situar-se em relação a eles. Em seguida, serão relatadas algumas observações a respeito de valores de professores e práticas daí decorrentes. São comentados resultados de pesquisa que ilustram a transmissão de valores de forma doutrinal e a educação moral e cívica tal como realizada na ditadura militar, e, por outro lado, a posição relativista e/ou de laissez-faire que certas escolas podem adotar, metodologicamente, sobre a educação em valores. Finalmente, defender-se-á a idéia de que é necessária uma discussão sobre valores pelos diversos membros da escola e uma opção por uma metodologia para ensiná-los, seja os professores, em sua formação inicial e continuada, seja os alunos. A teoria de desenvolvimento moral de Jean Piaget será apresentada como uma referência possível para a educação em valores. Exemplos de situações escolares de conflito de valores entre direção, pais e alunos são discutidas para ilustrar como uma escola pode adotar um procedimento democrático de educação em valores, que se apresenta como um terceiro caminho possível de educação moral nas escolas, além das posições doutrinárias ou relativistas.

  8. A aposta na filosofia

    Directory of Open Access Journals (Sweden)

    Márcio Suzuki

    2011-12-01

    Full Text Available Para Hume, filosofar é uma atividade semelhante às demais ocupações humanas. A decisão que leva à atividade filosófica é menos resultado de uma argumentação teórica do que fruto de um cálculo prático, que é entendido como uma caça ou um jogo. O objetivo deste trabalho será o de mostrar que no jogo filosófico perde quem joga sério demais. A aposta na filosofia tem que passar pelo bom humor e pela diversão: uma resposta a Pascal?For Hume, philosophy is in itself neither more nor less important than other human activities. On the contrary, it can be explained from its resemblance with game and hunting. If one chooses to dedicate himself to philosophy, his decision is not the consequence of logical reasoning, but depends on practical evaluation, which has something to do with gambling. The following text tries to show that in philosophy, like in other games, the loser will be the one who plays too earnestly. The philosophical game requires good humour and some relaxation: Is this a good answer to Pascal's pari?

  9. VPLIV OSEBNOSTI NA STILE VODENJA

    OpenAIRE

    Vučak, Petra

    2009-01-01

    Nekatere naše vrline krasijo zlate lastnosti, druge pa kvarijo sivi odtenki. Če bi ljudje razumeli in spoznali svojo osebnost, ter osebnostne tipe drugih ljudi, bi se problemi pri komunikaciji občutno zmanjšali. Takrat bi namreč lažje uvideli, zakaj je nekdo reagiral na način, kot je ali zakaj je nekdo dejal to, kar je. Smisel tega je, da spoznamo svoje dobre lastnosti, ki jih lahko še bolj razvijemo, slabe pa poskušamo nadzorovati in tako zmanjšati njihov vpliv. Iskanje uspešnih in učink...

  10. SPOLNO NADLEGOVANJE NA DELOVNEM MESTU

    OpenAIRE

    Rubič, Gašper

    2016-01-01

    V diplomskem delu smo v uvodu predstavili problem spolnega nadlegovanja na delovnem mestu in predstavili podjetje TEKSTIL d.d. V nadaljevanju smo z anketo raziskali, ali problem spolnega nadlegovanja na delovnem mestu v obravnavanem podjetju obstaja in če, kako se nanj odziva okolje. V teoretičnem delu smo nadaljevali in predstavili definicijo spolnega nadlegovanja, ki je kakršna koli oblika nezaželenega verbalnega in neverbalnega ali fizičnega ravnanja spolne narave z učinkom ali nameno...

  11. Active transport of Na+ by reconstituted Na,K-ATPase

    International Nuclear Information System (INIS)

    Boldyrev, A.A.; Svinukhova, I.A.

    1987-01-01

    The ability of ATP, CTP, ITP, GTP, and UTP to support ouabain-sensitive accumulation of Na + by proteoliposomes with a reconstituted Na/K-pump was investigated. At a low [Na + ]/[K + ] ratio in the medium (20 mM/50 mM), a correlation is observed between the proton-accepting capacity of the nucleotide and its effectiveness as a substrate of active transport. To test the hypothesis of the importance of the presence of a negative charge in the 1-position of the purine (3-pyrimidine) base of the nucleotide for mutual transitions between the Na- and K-conformations of Na,K-ATPase they used two analogs of ATP: N 1 -hydroxy-ATP, possessing proton acceptor capacity, and N 1 -methoxy-ATP, in the molecule of which the negative charge is quenched by a methyl group. The first substrate supports active accumulation of Na + in proteoliposomes at the same rate as ATP, whereas the second substrate is relatively ineffective

  12. Beam monitoring at NA2

    CERN Multimedia

    1978-01-01

    Claus Goessling working on the beam Cerenkov counter of NA2. The muon beam enters from left the hall EHN2 and the last element of the beam transport. On background is the access door on the Jura side.

  13. Risbjerg: Historisk stemmeskred med NA

    DEFF Research Database (Denmark)

    Thomsen, Søren Risbjerg

    2007-01-01

    ANALYSE: NA flytter 12,3 pct. af stemmerne i majs meningsmålinger - historisk mange vælgere på en måned, skriver professor Risbjerg. Udgivelsesdato: 3. juni 2007......ANALYSE: NA flytter 12,3 pct. af stemmerne i majs meningsmålinger - historisk mange vælgere på en måned, skriver professor Risbjerg. Udgivelsesdato: 3. juni 2007...

  14. Na via do Behemoth

    Directory of Open Access Journals (Sweden)

    Gérard Rabinovitch

    2008-06-01

    Full Text Available O momento nazista permanece um enigma impensado de que a cultura contemporânea continua cativa. O autor levanta a hipótese de que a persistência desse enigma e seus estragos duráveis se devem à insistência dos pensamentos político, sociológico e filosófico em construírem o nazismo à luz da metáfora hobbesiana do Leviatã. Propõe retomar a questão do nazismo sob a perspectiva do Behemoth, antônimo do Leviatã. Para tanto, sugere a necessidade de retornar a Freud e à psicanálise, balizas de um possível novo pensamento do político que escrutine a destrutividade nazista. Propõe ainda sondar as homologias entre nazismo, corjas e máfias, com base na figura da " heroicização da violência" que lhes seria comum. E avança um modelo " econômico" : a quimera, suscetível de capturar o caráter heterotópico e heterocrônico de sua construção criminosa.The paths of Behemoth. The Nazi moment remains as the thoughtless enigma of which contemporary culture is still captive. The author raises the hypothesis where the persistency of this enigma and its durable damages are due to the insistence of the political, social and philosophical thoughts in building the Nazism at the view of the Hobbesian metaphor of Leviathan. It is here proposed to resume the Nazism matter under Behemoth's perspective, antonym to Leviathan. For such, it is suggested a necessity to look back at Freud and the psychoanalysis, structured by a possible new political thought which scrutinizes the destructivity of the Nazism. It is also here proposed to gaze at the homologies between Nazism, mafias and gangs, with a base in the figure of " violence as a heroically act" that are their common ground. The author also advances an economical model: the chimera susceptible to capture the heterotopic and heterochronic character of its criminal construction.

  15. Nonthyroidal illness syndrome in patients with subarachnoid hemorrhage due to intracranial aneurysm Sindrome da doença não tiroideana em pacientes com hemorragia subaracnoidea devida a aneurisma cerebral

    Directory of Open Access Journals (Sweden)

    Luiz Augusto Casulari

    2004-03-01

    os níveis séricos de triiodotironina (T3 e T3 reverso foram medidos. As amostras de sangue foram obtidas entre 8:00 e 9:00. Os seguintes resultados foram obtidos: o grupo SH teve menores níveis de T3 e T4 livre do que o grupo BDS (p<0,05: T3 (ng/ml: SH = 58,7±1,1 e BDS = 74,5±13,9; T4 livre (ng/dl: SH = 0,9±0,2 e BDS = 1,1±0,3. Não ocorreram diferenças significativas nos níveis de tiroxina total (T4 e de hormônio estimulante da tireóide (TSH entre os dois grupos: T4 (µg/dl: SH = 6,9±1,1 e BDS = 7,4±2,1; TSH (µUI/ml: SH = 1,5±0,8 e BDS = 1,8±1,0. Na amostra de oito pacientes de cada grupo tivemos os seguintes resultados: T3 (ng/ml: SH = 66,8±3,8 e BDS = 77,2±1,1 (p <0,05; T3 reverso (ng/dl: SH = 32,8±8 e BDS = 24,7±2,2 (NS; relação T3/ T3 reverso: SH = 2,6±0,3 e BDS = 3,3±0,4 (NS. Anticorpos antitireoglobulina e antimicrossomal não foram detectáveis, exceto em um paciente no grupo SH. Em conclusão: os pacientes com SH apresentam níveis séricos de T3 e T4 livre significativamente menores do que aqueles com BDS; o perfil hormonal tireoidiano sugere que os pacientes com SH desenvolvem a síndrome da doença não tireoidiana.

  16. Manifestações renais na síndrome de Joubert Renal symptoms in the Joubert syndrome

    Directory of Open Access Journals (Sweden)

    Ana Paula Weiss

    2009-06-01

    Full Text Available OBJETIVO:Descrever o caso clínico de paciente com Síndrome de Joubert associada a alterações renais. DESCRIÇÃO DO CASO: Paciente de dois meses de idade admitida com quadro hipotonia e hiperpneia. Ao exame físico, observaram-se, além da respiração irregular, movimentos oculares anormais e hipertensão arterial; não se evidenciaram alterações na ausculta cardíaca e pulmonar. Durante investigação clínico-laboratorial inicial, as causas cardíacas e pulmonares foram descartadas. Aventaram-se hipóteses diagnósticas de patologias neurológicas com doença renal. Os exames laboratoriais mostraram presença de alcalose respiratória, acidose metabólica e hipercalemia, com função renal normal. A ressonância magnética evidenciou alterações neurológicas compatíveis com "sinal do dente molar", quadro frequentemente associada à Sindrome de Joubert. Levando-se em consideração a associação dessa síndrome com alterações renais, a investigação nefrológica demonstrou imagens císticas em parênquima renal. COMENTÁRIOS: Patologias cardíacas e pulmonares estão frequentemente associadas a manifestações clínicas como taquipneia e distúrbios metabólicos. Entretanto, pode ser necessária uma investigação neurológica porque diversas doenças que acometem o sistema nervoso central apresentam tais alterações. A associação entre alterações renais e malformações de sistema nervoso central é frequente em diversos processos sindrômicos, justificando-se a sua investigação. A Síndrome de Joubert e as desordens a ela relacionadas caracterizam-se por aplasia do vermix cerebelar, ataxia, movimentos oculares anormais, respiração irregular e retardo do desenvolvimento neuropsicomotor. As alterações renais mais comuns são os cistos renais e a nefronoftise, que pode progredir para doença renal terminal.OBJECTIVE:To describe the case of a patient with Joubert syndrome associated with renal impairments. CASE

  17. Financiranje projekata na pomorskom dobru

    Directory of Open Access Journals (Sweden)

    Zoran Tasić

    2018-02-01

    Full Text Available Koncesije otvaraju vrlo osjetljiva politička, ekonomska i pravna pitanja u mnogim državama svijeta. Samo definiranje pojma koncesije često je komplicirana i ne sasvim jasna zadaća. OECD je prihvatila definiciju koncesije kao: ’’davanje prava privatnom trgovačkom društvu da može gospodarski upravljati određenom infrastrukturnim uslugama i za to zarađivati naknadu. Koncesionar dobija u posjed određene objekte (ali vlasništvo na tim objektima ostaje u rukama države te ih koristi u svrhu obavljanja određene djelatnosti ili usluge sukladno odredbama ugovora’’. Hrvatsko pravo definira koncesije načelno kao pravo stečeno temeljem ugovora o koncesiji, a sukladno uvjetima sadržanim u odluci o davanju koncesije (koju je donijelo odgovarajuće upravno tijelo, a u odnosu na pomorsko dobro, specifično, kao pravo državne vlasti da može dio pomorskog dobra, koje je inače dobro izvan pravnog prometa (res extra commercium, isključiti iz opće uporabe bilo dijelom ili u cijelosti, i dati ga fizičkoj ili pravnoj osobi na gospodarsko korištenje sukladno određenim prostornim planovima. Građevine i drugi objekti izgrađeni na pomorskom dobru čine njegov sastavni dio. Zakonom je jasno određeno da nikakva stvarna prava nisu dopuštena na pomorskom dobru, uključivo i na objektima izgrađenima na njemu. Projekti na pomorskom dobru često uključuju velike infrastrukturne projekte, razvoje luka i marina, koji iziskuju značajna financijska sredstva. Banke koje financiraju takve projekte zahtijevaju organiziran i transparentan zakonski okvir koncesija, slobodu ugovaranja, pravnu zaštitu svih strana uključenih u projekt (uključivo i mogućnost međunarodne arbitraže. (...

  18. Recikliranje plastenk na kreativen način

    OpenAIRE

    Pavlin, Suzana

    2017-01-01

    Plastenke, poleg ostalih plastičnih izdelkov, v zadnjih letih predstavljajo pravo katastrofo za okolje. Domnevamo, da se le redko kdo vpraša, kaj se zgodi z njo po tem, ko je iz nje zaužil še zadnjo kapljico vode. Plastenka je lahko kot večina ostalih komunalnih odpadkov ponovno uporabljena, reciklirana, sežgana ali odložena na deponijo. V primeru nespoštovanja Zakona o varstvu okolja pa pristane v naravi, pogosto v morju, kjer prav počasi razpada in negativno vpliva na celoten ekosistem. V d...

  19. All new for NA62

    CERN Multimedia

    Antonella Del Rosso

    2012-01-01

    This week sees the start of the first run of the new NA62 experiment. This will be a unique opportunity for the collaboration to test its new beam, new detectors and new data acquisition system before the physics run in 2014. Speaking to the Bulletin, the NA62 technical coordinator Ferdinand Hahn shares the many challenges that the various teams faced to be on time for beam. Ready, steady, start!   A Large Angle Veto detector (white) in place in the NA62 decay volume (blue). With components from almost all the detectors in place downstream of the decay point of the mother particles – the kaons – and of the KTAG detector that tags the kaons before they decay, NA62 is ready for its first technical run. This unique run will test all the equipment as well as the trigger and the data acquisition systems. “This year, we will have about five weeks of beam from the SPS before the long shutdown of all the CERN machines,” says Ferdinand Hahn, NA62 Technical Co-...

  20. Corpo e sexualidade na gravidez

    Directory of Open Access Journals (Sweden)

    Natalúcia Matos Araújo

    2012-06-01

    Full Text Available Estudo etnográfico que teve como objetivo compreender como as gestantes vivenciam os processos fisiológicos do seu corpo durante a gestação e a sua repercussão na sexualidade. A pesquisa envolveu sete mulheres residentes em bairro popular de São Paulo. Na coleta de dados, utilizou-se observação participante e entrevista com questões norteadoras. Os dados foram apresentados na forma de narrativa e posteriormente organizados nas categorias: Percebendo as transformações corporais; Convivendo com as mudanças no corpo; Sentimentos e sensações na vida sexual durante a gestação e imaginando o corpo e a sexualidade após a gestação. As mulheres referiram-se às transformações do corpo como desconfortos e expressaram a preocupação de que fossem definitivas. Expressaram o desejo de que, após o parto, o corpo volte a ser como era e que volte a sentir desejo sexual. O reconhecimento destes fatos constitui-se numa ferramenta primordial na adequação das práticas profissionais.

  1. gigapanorama of NA 62 cavern

    CERN Multimedia

    Brice, Maximilien

    2015-01-01

    The image shows the new rare Kaon decay experiment at CERN, called NA62. The NA62 experiment is 270 metres long and includes a 120-metre-long vacuum tank, shown here, housing several of the particle detectors. (Note: the experiment axis is a straight line, the curving of the tank is an optical effect of the photo.) Kaons are particles that decay into lighter elementary particles. The kaon decay processes are mostly well known, except for some very rare decay modes. For example, NA62 is investigating a rare decay predicted by the Standard Model in which a kaon decays into one pion and two neutrinos. This process occurs only once every 10 billion decays. The understanding of such ultra-rare decays are of great importance because they test the Standard Model in energy ranges not accessible by direct measurements. They are therefore complementary to the measurements at the LHC. ultra high definition on demand (photolab@cern.ch).

  2. Armas na escola: que fazer?

    Directory of Open Access Journals (Sweden)

    Raymundo de Lima

    2010-09-01

    Full Text Available

    Um aluno portava um revólver na sala de aula de uma escola de Maringá (O Diário, 30/07/2010. Ele pegou arma do pai, sem que este soubesse, para se proteger de garotos que o intimidavam. Trata-se de um caso isolado ou é hora de a escola tomar medidas preventivas? Semanas antes, tiros foram disparados dentro de uma faculdade da mesma cidade. O autor dos disparos está preso, e a faculdade tenta apagar as marcas com publicidade positiva na Tv. Em Campo Mourão, cidade a cerca de uma hora de Maringá, duas meninas foram mortas e enterradas na escola.

  3. OGLAŠEVANJE NA FACEBOOKU

    OpenAIRE

    Renko, Katica

    2013-01-01

    V magistrskem delu smo se seznanili z oglaševanjem na Facebooku. S pregledom gradiva, ki nam je ponujeno, smo preverili pogoje, načine, oblike … oglaševanja, ki pa smo jih s pregledom situacije v praksi preverili in dopolnili. Ob zaključku dela lahko rečemo, da je oglaševanje preko FB enostavnejše, cenejše, dostopnejše, omogoča nam ažurnost in samo komunikacijo z naslovniki, ki so potencialni kupci naših ponudb. Množični mediji nam omogočajo mnogotero obliko oglaševanja. Izbrana oblika ponuja...

  4. Congenital Primary Pachydermoperiostosis and Striate Palmoplantar Keratoderma - a Case Report

    Directory of Open Access Journals (Sweden)

    Stojanović Slobodan

    2014-06-01

    Full Text Available Uvod. Pahidermoperiostoza (PDP predstavlja heterogeni sindrom za koji su karakteristične hipertrofi čne promene prvenstveno kože i kostiju ekstremiteta: pahidermija, klabing (clubbing prstiju šaka i stopala i hipertrofi čna osteoartropatija. Primarna pahidermoperiostoza − sinonim Turen−Solent−Goleov sindrom (Touraine-Solente-Golé (PPDP, ili primarna hipertrofi čna osteoartropatija (PHO, redak je nasledni poremećaj i predstavlja jedan od dva tipa hipertrofi čne osteoartropatije.

  5. β decay of Na32

    Science.gov (United States)

    Mattoon, C. M.; Sarazin, F.; Hackman, G.; Cunningham, E. S.; Austin, R. A. E.; Ball, G. C.; Chakrawarthy, R. S.; Finlay, P.; Garrett, P. E.; Grinyer, G. F.; Hyland, B.; Koopmans, K. A.; Leslie, J. R.; Phillips, A. A.; Schumaker, M. A.; Scraggs, H. C.; Schwarzenberg, J.; Smith, M. B.; Svensson, C. E.; Waddington, J. C.; Walker, P. M.; Washbrook, B.; Zganjar, E.

    2007-01-01

    The β-decay of Na32 has been studied using β-γ coincidences. New transitions and levels are tentatively placed in the level scheme of Mg32 from an analysis of γ-γ and β-γ-γ coincidences. The observation of the indirect feeding of the 2321 keV state in Mg32 removes some restrictions previously placed on the spin assignment for this state. No evidence of a state at 2117 keV in Mg32 is found. Previously unobserved weak transitions up to 5.4 MeV were recorded but could not be placed in the decay scheme of Na32.

  6. Corpo-escrita na esquizofrenia

    OpenAIRE

    Bialer, Marina

    2014-01-01

    Este artigo aborda a importância do trabalho de escrita na esquizofrenia. Toma-se como ponto de partida a formulação lacaniana sobre o esquizofrênico como aquele que não tem as funções dos órgãos do seu corpo dadas pelos discursos estabelecidos. A hipótese de que o trabalho sobre a letra pode permitir o tratamento do gozo debordante na esquizofrenia é analisada pelo estudo da obra do escritor esquizofrênico Robert Walser, a qual evidencia a viabilidade da construção de um corpo pela escrita n...

  7. Meltability in system of K2TaF7-NaF-NaCl-KCl

    International Nuclear Information System (INIS)

    Kartsev, V.E.; Kovalev, F.V.; Korshunov, B.G.

    1975-01-01

    Thermographic and visual-polythermal techniques were used to study the meltability in K 2 TaF 7 -NaF-NaCl-KCl system. The tetrahedron-forming sections NaF-NaCl-K 2 TaF 7 xKCl and NaF-K 2 TaF 7 xKCl-2K 2 TaF 7 xNaCl divide the concentration tetrahedron into three particular tetrahedra: NaF-K 2 TaF 7 xKCl-2K 2 TaF 7 xNaCl-K 2 TaF 7 , NaF-NaCl-K 2 TaF 7 xKCl-2K 2 TaF 7 xaCl, and NaF-NaCl-KCl-K 2 TaF 7 xKCl. Non-variant equilibrium points in all of the particular four-component systems have been determined

  8. NA60 frees the quarks

    CERN Multimedia

    2003-01-01

    Fitted with new state-of-the-art silicon detectors, NA60 is prepared to study the phase transition from confined hadronic matter to a deconfined (free) quark-gluon plasma, a state of matter which probably existed an instant after the Big Bang.

  9. NA61/SHINE ion program

    CERN Document Server

    Mackowiak, Maja

    2010-01-01

    The Super Proton Synchrotron (SPS) at CERN covers one of the most interesting regions of the phase diagram (T - \\mu_{B}) of strongly interacting matter. The study of central Pb+Pb collisions by NA49 indicate that the threshold for deconfinement is reached already at the low SPS energies. Theoretical considerations predict a critical point of strongly interacting matter at energies accessible at the SPS. The NA61/SHINE experiment, a successor of the NA49 project, will study hadron production in p+p, p+A, h+A, and A+A reactions at various energies. The broad physics program includes the investigation of the properties of strongly interacting matter, as well as precision measurements of hadron spectra for the T2K neutrino experiment and for the Pierre Auger Observatory and KASCADE cosmic-ray projects. The main physics goals of the NA61/SHINE ion program are to study the properties of the onset of deconfinement at low SPS energies and to find signatures of the critical point of strongly interacting matter. To ach...

  10. NA62: Hidden Sector Physics

    CERN Document Server

    Cesarotti, Carissa Joyce

    2016-01-01

    Modern experimental physics is often probing for new physics by either finding deviations from predictions on extremely precise measurements, or by looking for a new signal that cannot be explained with existing models. The NA62 experiment at CERN does the former by measuring the ultra-rare decay $K^+ \\rightarrow \\pi^+ \

  11. The system NaVO3-Na2WO4-Na2W2O7

    International Nuclear Information System (INIS)

    Kazanbekov, V.R.; Gasanaliev, A.M.; Kazanbekov, R.G.

    1994-01-01

    Phase diagrams of sodium metavanadate-sodium ditungstate, sodium metavanadate-sodium tungstate systems and surface of primary crystallization of sodium metavabadate-sodium tungstate-sodium ditungstate system were studied. The system sodium metavanadate-sodium ditungstate is eutectic one. Compound NaVO 3 x2Na 2 WO 4 is formed in solid state in sodium metavanadate-sodium tungstate system. Liquidus surface of sodium metavanadate-sodium tungstate-sodium ditungstate is presented by three crystallization fields of initial components. Composition and melting point of ternary eutectics are determined

  12. Europlanet NA2 Science Networking

    Science.gov (United States)

    Harri, Ari-Matti; Szego, Karoly; Genzer, Maria; Schmidt, Walter; Krupp, Norbert; Lammer, Helmut; Kallio, Esa; Haukka, Harri

    2013-04-01

    Europlanet RI / NA2 Science Networking [1] focused on determining the major goals of current and future European planetary science, relating them to the Research Infrastructure that the Europlanet RI project [2] developed, and placing them in a more global context. NA2 also enhanced the ability of European planetary scientists to participate on the global scene with their own agenda-setting projects and ideas. The Networking Activity NA2 included five working groups, aimed at identifying key science issues and producing reference books on major science themes that will bridge the gap between the results of present and past missions and the scientific preparation of the future ones. Within the Europlanet RI project (2009-2012) the NA2 and NA2-WGs organized thematic workshops, an expert exchange program and training groups to improve the scientific impact of this Infrastructure. The principal tasks addressed by NA2 were: • Science activities in support to the optimal use of data from past and present space missions, involving the broad planetary science community beyond the "space club" • Science activities in support to the preparation of future planetary missions: Earth-based preparatory observations, laboratory studies, R&D on advanced instrumentation and exploration technologies for the future, theory and modeling etc. • Develop scientific activities, joint publications, dedicated meetings, tools and services, education activities, engaging the public and industries • Update science themes and addressing the two main scientific objectives • Prepare and support workshops of the International Space Science Institute (ISSI) in Bern and • Support Trans National Activities (TNAs), Joined Research Activities (JRAs) and the Integrated and Distributed Information Service (IDIS) of the Europlanet project These tasks were achieved by WG workshops organized by the NA2 working groups, by ISSI workshops and by an Expert Exchange Program. There were 17 official WG

  13. Pozitivni in negativni vplivi risank na otroke

    OpenAIRE

    Povše, Nika

    2017-01-01

    V tej diplomski nalogi smo raziskovali pozitivne in negativne vplive risank na otroke. Začeli smo z zgodovino televizije, tako svetovno zgodovino kot zgodovino televizije na Slovenskem. Na isti način smo pregledali tudi zgodovino risank. Raziskovali smo otrokov razvoj, predvsem tiste vidike, ki so izpostavljeni vplivom risank, kot so morala, jezik, domišljija in učenje. Sledilo je raziskovanje negativnih in pozitivnih vplivov, ki jih imajo risanke na otroke, kar je tudi naš glavni problem te ...

  14. Sindrome de Vogt-Koyanagi-Harada: relato de um caso

    Directory of Open Access Journals (Sweden)

    José Geraldo Camargo Lima

    1978-03-01

    Full Text Available É relatado um caso de síndrome de Vogt-Koyanagi-Harada que se iniciou por um quadro oftálmico inicialmente unilateral e, depois, bilateral. Um mês após o início da doença manifestou-se um quadro psiquiátrico tipo mania com fugas de idéias, euforia e diminuição do senso crítico. As alterações encontradas nos eletrencefalogramas e exames de líquido cefalorraqueano são analisadas. O caso foi seguido durante três anos e meio e apesar de ter sido submetido a corticoterapia teve má evolução do ponto de vista oftalmológico. Do ponto de vista psiquiátrico evoluiu bem. não restando sequela alguma.

  15. Sindrome de Vogt-Koyanagi-Harada: relato de dois casos

    Directory of Open Access Journals (Sweden)

    Paulo E. Marchiori

    1981-12-01

    Full Text Available Os autores relatam a síndrome de Vogt-Koyanagi-Harada em duas mulheres adultas e de cor parda. São discutidos os aspectos clínicos, epidemiológicos, heredofamiliares e imunológicos.

  16. Zollinger-Ellison syndrome; Sindrome de Zollinger-Ellison

    Energy Technology Data Exchange (ETDEWEB)

    Muraro, Cirilo Luiz de Pardo Meo; Cunha, Hercio Azevedo de Vasconcelos; Freitas Junior, Carlos Eduardo de [Pontificia Univ. Catolica de Campinas, SP (Brazil). Faculdade de Ciencias Medicas. Hospital e Maternidade Celso Pierro

    2000-12-01

    The authors report a 49 years old, female patient who have been operated on several times (antrectomy with Billroth II reconstruction, partial gastrectomy with troncular vagotomy and total gastrectomy) in the last 5 years for recurrent ulcer disease. Three months ago, an abdomen ultra sound was done showing multiples images that suggested liver metastasis, which was confirmed by CT and MR. Two months ago, one new abdomen CT specifically to pancreas was done showing an expansive process in pancreas. Serial gastrine was 1532 pg/ml at the time (reference - until 115) and among clinical history and images exams Zollinger-Ellison Syndrome was suggested, a rare disease case. (author)

  17. Noonan syndrome and chylothorax; Sindrome de Noonan y quilotorax

    Energy Technology Data Exchange (ETDEWEB)

    Martinez-Leon, M. I.; Ceres-Ruiz, L.; Solbes-Vila, R.; Valls-Moreno, E. [Hospital Infantil del C.H.U. Carlos Haya. Malaga (Spain)

    2001-07-01

    Chylothorax during childhood usually develops as a result of posto-perative complications following cardiothoracic surgery. It is rarely due to the malformations of the lymphatic system associated with dysmorphic syndrome. We report two cases of Noonan syndrome involving neonatal development of chylothorax. In children with the Noonan phenotype who develop pleural effusion during the neonatal period in the absence of obstetric trauma, it is advisable to rule out the presence of congenital lymphatic malformation and study the pleural effusion, initially introducing conservative treatment with dietary therapy. Chest radiography, ultrasound and computed tomography reveal the presence of the pleural effusion and parenchymal pattern compatible with chloroethoxy and lymphangiectasis. (Author) 15 refs.

  18. EPR - spektroskopiya pri ozhirenii i metabolicheskom sindrome u zhenshchin

    Directory of Open Access Journals (Sweden)

    A G Maksina

    2001-03-01

    Full Text Available Цель. Исследовать изменения в структуре мембран эритроцитов крови при ожирении в сочетании с другими нарушениями, характерными для метаболического синдрома. Материалы и методы. Обследованы 42 пациентки в возрасте от 23 до 50 лет с избыточной массой тела и ожирением и контрольная группа (12 женщин с применением метода спинового зонда. Результаты. У пациенток и избытком массы тела и ожирением показатель мембранной упорядоченности фосфолипидов был выше, чем в контроле. . Изменение параметра S в цельной крови и сыворотке более выражено по сравнению с таковым в эритроцитах. При ожирении с сопутствующей артериальной гипертензией параметр упорядоченности достоверно выше (р

  19. LA SINDROME OSSESSIVA SPAZIO-TEMPORALE DEGLI ITALIANI

    African Journals Online (AJOL)

    User

    “Spazio e tempo sono maledizioni che gravano sulla terra”. La citazione è tratta dall'opera Trunkene Flut del 1949, tradotta in italiano con il titolo Flutto ebbro (a cura di A.M. Carpi, Guanda, Parma, 1989). Il pessimismo è una delle caratteristiche principali di Gottfried Benn (1886-1956), medico di professione, autore anche ...

  20. SINDROME DE BURNOUT E SUAS CONSEQUENCIAS NOS PROFISSIONAIS DE ENFERMAGEM

    Directory of Open Access Journals (Sweden)

    Clecilene Gomes CARVALHO

    2011-01-01

    Full Text Available Burnout is an English word that refers to something that crashed from exhaustion. It is a problem that affects service professionals, particularly those facing care activities with others, in which the provision of care or service often occurs in situations of emotional changes. The syndrome takes a multidimensional concept, whosemanifestation is characterized by emotional exhaustion, reduced personal accomplishment and depersonalization of the other. Taking into consideration that nurses, technicians and nursing assistants, are a great group with a predisposition to develop the syndrome because they are health professionals who spend more time in contact with the patient and their family members within the work environment emotional situations of constant change, we performed abibliographic review in order to gather information on key risk factors that favor the onset of the Burnout syndrome and its consequences for the individual, organization and society. This work will serve as a subsidy for reflection and discussion, both the professionals involved, as future managers and professionals.

  1. Aplicacion de la ozonoterapia en el sindrome cocleovestibular

    OpenAIRE

    Alejandro del Cerro; Silvia Menéndez; Tania Alvarez

    2010-01-01

    Se les llama síndromes cócleo-vestibulares a un grupo de afecciones caracterizadas por alteraciones de la audición y del equilibrio. Son motivos frecuentes de consulta médica y de elevado ausentismo laboral. El vértigo es el síntoma principal, aunque la hipoacusia, los acúfenos, el dolor y la sensación de humedad pueden estar presentes. Esta afección tiene una importante prevalencia y representa un alto costo económico, debido a la gama de medicamentos utilizados y prolongados tratamientos qu...

  2. [Polycystic ovary sindrome: impact on reproductive and material fetal health].

    Science.gov (United States)

    Fux Otta, Carolina; Iraci, Gabriel Santino; Szafryk de Mereshian, Paula; Fiol de Cuneo, Marta

    2016-01-01

    Polycystic ovary syndrome (PCOS) is characterized by hyperandrogenism (H), oligo-anovulation (O) and / or polycystic ovaries (P). There is currently little information on perinatal complications. to investigate obstetric and neonatal characteristics of women with PCOS in our population. we studied 87 pregnant women with PCOS (categorized in four phenotypes according Rotterdam Consensus: A (H + O + P) n = 53; B (H + O) n = 9; C (H + P) n = 16 and D (O + P) n = 9) and 96 without PCOS (control). We analyzed clinical and biochemical features (age, anthropometry hirsutism, acanthosis nigricans, OGTT, insulin, lipid profile, androgen and gonadotropins) during preconception, (weight gain, blood pressure, OGTT) through gestation and occurrence of perinatal complications. we found no differences in age (29.4 ± 4 and 28.7 ± 5 years) and body mass index (28.2 ± 6 and 27.8 ± 6 kg / m2) in both groups; while patients with PCOS had higher waist circumference, blood pressure and acanthosis nigricans versus control. Despite similar weight gain, patients with PCOS had higher percentage of perinatal complications. In the A phenotype RR for perinatal adverse outcomes was 2.37 (95%CI: 1.67-3.36, p <0.001). The HOMA-IR index preconception and fasting glucose during pregnancy were the predictors for these complications (p=0.01). patients with PCOS have a higher risk for complications during pregnancy and newborns more frequently have low weight or macrosomy. A careful history can recognize patients with higher perinatal risk to develop complications.

  3. SINDROME DE SILVER-RUSSELL, REPORTE DE UN CASO

    Directory of Open Access Journals (Sweden)

    Ángela Liliana Grandas Ramírez

    2012-07-01

    Full Text Available El síndrome Silver-Russell es un desorden genético (hipometilación en la región centro 1 (ICR1 del  IGF2 /H19  locus 11p15 y clínicamente heterogéneo, caracterizado por retardo del crecimiento intrauterino, baja talla y peso, y perímetro cefálico normal. Su tratamiento se basa en la  hormona del crecimiento. Se presenta el caso de una niña de 5 años que ingresa al servicio de Estomatología Pediátrica de la Fundación HOMI Hospital de la Misericordia de Bogotá, con antecedente de retardo del crecimiento intrauterino, manejada con dieta rica en carbohidratos y uso de biberón hasta los 2 y medio años, Al examen talla 88 cm y peso 9 Kg,  cara forma triangular, frente prominente, micrognatismo mandibular, apiñamiento dental y caries de la infancia temprana. Se diagnostica con retardo de la edad ósea, dental y morfológica. El tratamiento programa individual riesgo de caries y proveer una alta calidad de salud oral.

  4. Ejercicio, Obesidad y Sindrome Metabólico

    Directory of Open Access Journals (Sweden)

    A. Carlos Jorquera, Nut. Msc

    2012-05-01

    Full Text Available Los bajos niveles de actividad física y/o ejercicio, junto a los malos hábitos alimentarios presentes a nivel nacional e internacional, han traído consigo una serie de complicaciones y/o morbilidades que han provocado un importante aumento de las tasas de mortalidad por enfermedades adquiridas, muchas de ellas ligadas a esta malnutrición por exceso y sedentarismo, descritos en encuestas nacionales e internacionales. La falta de movimiento es extrema en la población chilena y mundial, cada día la industria desarrolla elementos que buscan disminuir la ejecución de ejercicio físico, lo que se refleja de cierta manera en las encuestas ejecutadas, donde las tasas de inactividad física son elevadísimas, tanto en adultos como en niños, ya sean estos hombres o mujeres. Esto, sumado a los elevados niveles de obesidad, hace que enfoquemos nuestra atención al desarrollo de un tratamiento que combata estos dos factores de riesgo de manera paralela, pues en la ecuación de Balance Energético un 50% de ella corresponde a la ingesta y un 50% al gasto de energía. Los elevados niveles de sobrepeso y obesidad de nuestra realidad chilena (60% de la población, son la evidencia de un balance energético positivo provocado por una mayor ingesta de alimentos y un menor gasto en actividad física lo que ha llevado a que aumente progresivamente el Síndrome Metabólico y las ECNT en nuestra población.

  5. Churg-Strauss syndrome; Sindrome de Churg Strauss

    Energy Technology Data Exchange (ETDEWEB)

    Ayala, Jose Javier; Velasquez, Juan Carlos

    2005-07-01

    Churg-Strauss Syndrome was described in 1951 and it is characterized by asthma, fever, hypereosinophilia and vasculitis. In 1990, following the discussion of several proposals for its classification, the American College of Rheumatology established its diagnostic criteria. A 55 year-old female patient was seen recently at the Military Hospital in Bogota, Colombia, with leucocytoclastic vasculitis, wheezing, pulmonary infiltrates and hypereosinophilia, who met all the criteria to be classified as a Churg-Strauss patient.

  6. Syndrome of Churg Strauss; Sindrome de Churg Strauss

    Energy Technology Data Exchange (ETDEWEB)

    Sanchez Morales, Edgar Alberto; Saavedra Rodriguez, Alfredo; Henao Riveros, Sandra

    2002-09-01

    The Churg-Strauss syndrome denominated allergic granulomatosis and angeitis is characterized by a systemic vasculitis of small glasses, extravascular granulomas and hypereosinophilia. Initially described by Jacob Churg and Lotte Strauss, two pathologists who in 1951 they published the description of 13 patient postmortem with tisular infiltration for eosinophils, necrotizant vasculitis and extravascular granulomas. The paper includes nomenclature, classification approaches, pathogenesis, pathology, and clinical aspects and diagnostic.

  7. SINDROMES HEREDITARIOS QUE PREDISPONEN AL DESARROLLO DEL CANCER COLORRECTAL

    Directory of Open Access Journals (Sweden)

    Dr. Benedito Mauro Rossi

    2017-07-01

    En ambos síndromes, el estudio genético de los pacientes permite en altos porcentajes identificar las mutaciones causantes. En base a estos resultados, se pueden identificar los familiares portadores de mutaciones, y ofrecerles los esquemas de vigilancia y eventuales tratamientos profilácticos correspondientes a su enfermedad. Para el manejo integral de estas familias es esencial contar con un equipo multidisciplinario, para poder ofrecer consejería genética, estudio genético, educación a las familias y tratamiento respectivo en forma adecuada.

  8. SINDROME DE SILVER-RUSSELL, REPORTE DE UN CASO

    Directory of Open Access Journals (Sweden)

    Ángela Liliana Grandas Ramírez

    2012-12-01

    Full Text Available El síndrome Silver-Russell es un desorden genético (hipometilación en la región centro 1 (ICR1 del  IGF2 /H19  locus 11p15 y clínicamente heterogéneo, caracterizado por retardo del crecimiento intrauterino, baja talla y peso, y perímetro cefálico normal. Su tratamiento se basa en la  hormona del crecimiento. Se presenta el caso de una niña de 5 años que ingresa al servicio de Estomatología Pediátrica de la Fundación HOMI Hospital de la Misericordia de Bogotá, con antecedente de retardo del crecimiento intrauterino, manejada con dieta rica en carbohidratos y uso de biberón hasta los 2 y medio años, Al examen talla 88 cm y peso 9 Kg,  cara forma triangular, frente prominente, micrognatismo mandibular, apiñamiento dental y caries de la infancia temprana. Se diagnostica con retardo de la edad ósea, dental y morfológica. El tratamiento programa individual riesgo de caries y proveer una alta calidad de salud oral.

  9. Na+-stimulated ATPase of alkaliphilic halotolerant cyanobacterium Aphanothece halophytica translocates Na+ into proteoliposomes via Na+ uniport mechanism

    Directory of Open Access Journals (Sweden)

    Soontharapirakkul Kanteera

    2010-08-01

    Full Text Available Abstract Background When cells are exposed to high salinity conditions, they develop a mechanism to extrude excess Na+ from cells to maintain the cytoplasmic Na+ concentration. Until now, the ATPase involved in Na+ transport in cyanobacteria has not been characterized. Here, the characterization of ATPase and its role in Na+ transport of alkaliphilic halotolerant Aphanothece halophytica were investigated to understand the survival mechanism of A. halophytica under high salinity conditions. Results The purified enzyme catalyzed the hydrolysis of ATP in the presence of Na+ but not K+, Li+ and Ca2+. The apparent Km values for Na+ and ATP were 2.0 and 1.2 mM, respectively. The enzyme is likely the F1F0-ATPase based on the usual subunit pattern and the protection against N,N'-dicyclohexylcarbodiimide inhibition of ATPase activity by Na+ in a pH-dependent manner. Proteoliposomes reconstituted with the purified enzyme could take up Na+ upon the addition of ATP. The apparent Km values for this uptake were 3.3 and 0.5 mM for Na+ and ATP, respectively. The mechanism of Na+ transport mediated by Na+-stimulated ATPase in A. halophytica was revealed. Using acridine orange as a probe, alkalization of the lumen of proteoliposomes reconstituted with Na+-stimulated ATPase was observed upon the addition of ATP with Na+ but not with K+, Li+ and Ca2+. The Na+- and ATP-dependent alkalization of the proteoliposome lumen was stimulated by carbonyl cyanide m - chlorophenylhydrazone (CCCP but was inhibited by a permeant anion nitrate. The proteoliposomes showed both ATPase activity and ATP-dependent Na+ uptake activity. The uptake of Na+ was enhanced by CCCP and nitrate. On the other hand, both CCCP and nitrate were shown to dissipate the preformed electric potential generated by Na+-stimulated ATPase of the proteoliposomes. Conclusion The data demonstrate that Na+-stimulated ATPase from A. halophytica, a likely member of F-type ATPase, functions as an electrogenic Na

  10. Photodesorption of Na atoms from rough Na surfaces

    DEFF Research Database (Denmark)

    Balzer, Frank; Gerlach, R.; Manson, J.R.

    1997-01-01

    We investigate the desorption of Na atoms from large Na clusters deposited on dielectric surfaces. High-resolution translational energy distributions of the desorbing atoms are determined by three independent methods, two-photon laser-induced fluorescence, as well as single-photon and resonance......-enhanced two-photon ionization techniques. Upon variation of surface temperature and for different substrates (mica vs lithium fluoride) clear non-Maxwellian time-of-flight distributions are observed with a cos θ angular dependence and most probable kinetic energies below that expected of atoms desorbing from...... atoms are scattered by surface vibrations. Recent experiments providing time constants for the decay of the optical excitations in the clusters support this model. The excellent agreement between experiment and theory indicates the importance of both absorption of the laser photons via direct excitation...

  11. Vpliv konfucija na sodobno izobraževanje na Kitajskem

    Directory of Open Access Journals (Sweden)

    Katja Skitek

    2009-12-01

    Full Text Available Izobraževanje na Kitajskem je bilo vedno trdno povezano s Konfucijem in konfucianizmom, kar pa ni čudno, saj je bil Konfucij prvi, ki je poudarjal moč z nanja in izobraževanja. LR Kitajska je v zadnjih petdesetih letih počasi in postopoma začela uveljavljati določene spremembe v vzgojno-izobraževalni sistem. Kakšne so te spremembe in koliko nanje še vedno vpliva konfucianizem, bo osrednja tema pričujočega članka. Konfucianizem danes na Kitajskem ni preveč popularen, izobraženci pa so se razporedili v dve skupini: eni trdijo, da je njegov vpliv še vedno velik, drugi pa zatrjujejo, da nima več nobenega vpliva na sodobno življenje. Katera stran ima prav? Konfucij je v prvi vrsti poudarjal pomembnost moralnih vrednot vsakega človeka in prav moralne vrednote, za katere se je zavzemal, so še danes trdno zasidrane v kitajski kulturi. Ali je torej sploh mogoče popolnoma izriniti Konfucija iz sodobnega izobraževanja?

  12. Novel aspects of Na+,K+-ATPase

    OpenAIRE

    Aizman, Oleg

    2002-01-01

    Na,K-ATPase, an integral membrane protein expressed in each eukaryotic cell, serves as the major determinant of intracellular ion composition. In the current study we investigated novel aspects of Na,K-ATPase function and regulation. It is well established that Na,K-ATPase activity is regulated by reversible phosphorylation. New findings in this study are: 1) the level of intracellular Ca 2. concentration determines the functional effects of PKA and PKC-mediated Na,K-ATP...

  13. NA64 Status Report 2018

    CERN Document Server

    Gninenko, Sergei

    2018-01-01

    The experiment NA64 is aimed at a search for a sub-GeV vector mediator (called dark photon A′) of Dark Matter production at the CERN SPS. . The main goal in 2017 was to probe a region of the A′ parameter space of the thermal dark matter model. Ongoing activities on the detector and data analysis are reviewed. The status and results from the NA64 runs in 2016 and 2017 are reported. First results on the search for the X->e+e− decay of a 17 MeV X boson, which could explain the recently observed excess of e+e-pairs from the excited 8Be nucleus transitions, and A'-> e+e- decays are also presented. Ongoing analysis on the decays of axion-like particles and plans for further searches beyond LS2 are also discussed.

  14. Makosa Yanayofanywa na Wanafunzi Wanaojifunza Kiswahili kama ...

    African Journals Online (AJOL)

    Makala haya, yanashughulika na makosa ambayo hufanywa na wanafunzi wanaojifunza Kiswahili kama lugha ya pili katika shule za sekondari nchini Uganda. Mtafiti ameyaainisha makosa mbalimbali na kuyaeleza kiusahihi. Makala yanaeleza namna ambavyo makosa hayo hutokea. Yaani, kama ni makosa ...

  15. Pseudo-ternary phase diagram in the Na2O-Na2O2-NaOH system

    International Nuclear Information System (INIS)

    Saito, Jun-ichi; Tendo, Masayuki; Aoto, Kazumi

    1997-10-01

    Generally, the phase diagrams are always used to understand the present state of compounds at certain temperature. In order to understand the corrosion behavior of structural material for FBR by main sodium compounds (Na 2 O, Na 2 O 2 and NaOH), it is very important to comprehend the phase diagrams of their compounds. However, only Na 2 O-NaOH pseudo-binary phase diagram had been investigated previously in this system. There is no study of other pseudo-binary or ternary phase diagrams in the Na 2 O-Na 2 O 2 -NaOH system. In this study, in order to clarify the present states of their compounds at certain temperatures, the pseudo-binary and ternary phase diagrams in the Na 2 O-Na 2 O 2 -NaOH system were prepared. A series of thermal analyses with binary and ternary component system has been carried out using the differential scanning calorimetry (DSC). The liquidus temperature and ternary eutectic temperatures were confirmed by these measurements. The beneficial indications for constructing phase diagrams were obtained from these experiments. On the basis of these results, the interaction parameters between compounds which were utilized for the Thermo-Calc calculation were optimized. Thermo-Calc is one of thermodynamic calculation software. Consequently the accurate pseudo-binary and ternary phase diagrams were indicated using the optimized parameters. (author)

  16. Na+,K+-ATPase Na+ affinity in rat skeletal muscle fiber types

    DEFF Research Database (Denmark)

    Kristensen, Michael; Juel, Carsten

    2010-01-01

    Previous studies in expression systems have found different ion activation of the Na(+)/K(+)-ATPase isozymes, which suggest that different muscles have different ion affinities. The rate of ATP hydrolysis was used to quantify Na(+),K(+)-ATPase activity, and the Na(+) affinity of Na(+),K(+)-ATPase...

  17. Homocisteína Homocysteine

    Directory of Open Access Journals (Sweden)

    Lindalva Batista Neves

    2004-10-01

    Full Text Available A homocisteína, formada a partir da metionina hepática, é metabolizada nas vias de desmetilação e de transulfuração, sendo que seus valores plasmáticos e urinários refletem a síntese celular. Sua determinação, realizada em jejum e após sobrecarga de metionina, caracteriza as diferenças dessas vias metabólicas, principalmente quando de natureza genética. A hiper-homocisteinemia tem sido associada a maior risco de eventos aterotrombóticos, e a literatura sugere associação causal, independente de outros fatores de risco para doença arterial. Diminuição da homocisteína plasmática para valores normais é seguida de redução significante na incidência de doença aterotrombótica. A relação entre homocisteína e o fígado vem adquirindo importância nos dias atuais, uma vez que alterações das lipoproteínas e da depuração de metionina são comuns em pacientes com doença hepática crônica (hepatocelular e canalicular. O tratamento da hiper-homocisteinemia fundamenta-se na suplementação alimentar e medicamentosa de ácido fólico e vitaminas B6 e B12.Homocysteine, formed from hepatic methionine, is metabolized through the pathways of demethylation and transsulfuration. Its plasmatic and urinary values reflect the cell synthesis. Its determination after fasting and increased infusion of methionine shows the differences of these two metabolic pathways, mainly when it is related to genetic diseases. Hyperhomocysteinemia has been associated with a higher risk of vascular thrombotic events. Several authors suggest a causal relationship between these events independently of other risk factors for vascular diseases. Decrease in plasmatic homocysteine to normal levels is followed by a significant reduction on the incidence of vascular thrombotic events. The correlation between the liver and homocysteine is becoming more important because of the recent findings that alterations of lipoproteins and methionine clearance are

  18. Myocardial Na,K-ATPase: Clinical aspects

    OpenAIRE

    Kjeldsen, Keld

    2003-01-01

    The specific binding of digitalis glycosides to Na,K-ATPase is used as a tool for Na,K-ATPase quantification with high accuracy and precision. In myocardial biopsies from patients with heart failure, total Na,K-ATPase concentration is decreased by around 40%; a correlation exists between a decrease in heart function and a decrease in Na,K-ATPase concentration. During digitalization, around 30% of remaining pumps are occupied by digoxin. Myocardial Na,K-ATPase is also influenced by other drugs...

  19. Crowdsourcing: impactos na performance na venda de produtos

    OpenAIRE

    Alves, Milton Ruiz Rodrigues

    2015-01-01

    Vivemos num momento em que as expectativas de pensadores como Lévy (1998), se concretizaram. O consumidor mudou, passou a exigir um diálogo entre a empresa e a sociedade. Esse novo cenário cobrou da tecnologia formas de aperfeiçoar e agilizar este processo de comunicação, plataformas baseadas na internet que propiciem e incentivam a troca de informações. Nesta esfera surgiu o crowdsourcing, com a disponibilização do capital intelectual das massas, que acabou por mudar a form...

  20. Silicene for Na-ion battery applications

    KAUST Repository

    Zhu, Jiajie

    2016-08-19

    Na-ion batteries are promising candidates to replace Li-ion batteries in large scale applications because of the advantages in natural abundance and cost of Na. Silicene has potential as the anode in Li-ion batteries but so far has not received attention with respect to Na-ion batteries. In this context, freestanding silicene, a graphene-silicene-graphene heterostructure, and a graphene-silicene superlattice are investigated for possible application in Na-ion batteries, using first-principles calculations. The calculated Na capacities of 954mAh/g for freestanding silicene and 730mAh/g for the graphenesilicene superlattice (10% biaxial tensile strain) are highly competitive and potentials of >0.3 V against the Na/Na potential exceed the corresponding value of graphite. In addition, the diffusion barriers are predicted to be <0.3 eV.

  1. Hali ya taaluma ya ukalimani Tanzania: jana, leo na kesho ...

    African Journals Online (AJOL)

    Umuhimu wa ukalimani katika mawasiliano umeongezeka kutokana na utandawazi. Utandawazi umerahisisha kukutanika na kuwasiliana kwa watu wazungumzao lugha tofauti kupitia wakalimani. Kutokana na ongezeko hilo la umuhimu wa ukalimani, kumekuwa na jitihada mbalimbali katika nchi mbalimbali kuhakikisha ...

  2. The Army vs. the People: The Opposition of the Soviet Military to Baltic Independence

    Science.gov (United States)

    1991-04-01

    untouched. General Fyodor Kuz’min, the commander of the Baltic Military District became Gorbachev’s de facto "Military Governer", the only powerful and... Sindrome ’, Neustavshchinye i Natsional’noi Aspekte Voinskoi Sluzhby" [Youth Try on Overcoats: on the ’Occupation Syndrome’, Non-Regulation Behavior, and...that despite the 4 V. Sein, "Komu na Ruku ’Antiarmeiskyi Sindrom ’?" [Who is Responsible for the ’Anti-Army Syndrome’?], Sovetskaya Latvia, July 5, 1989

  3. New results from NA49

    CERN Document Server

    Afanasiev, S V; Bächler, J; Barna, D; Barnby, L S; Bartke, Jerzy; Barton, R A; Behler, M; Betev, L; Bialkowska, H; Billmeier, A; Blume, C; Blyth, C O; Boimska, B; Botje, M; Bracinik, J; Brady, F P; Bramm, R; Brun, R; Buncic, P; Carr, L; Cebra, D; Cerny, V; Cooper, G E; Cramer, J G; Csató, P; Dinkelaker, P; Eckardt, V; Eckhardt, F; Ferenc, D; Filip, P; Fischer, H G; Foder, Z; Foka, P Y; Freund, P; Friese, V; Gál, J; Ganz, R E; Gazdzicki, M; Georgopoulos, G; Gladysz-Dziadus, E; Harris, J W; Hegyi, S; Höhne, C; Igo, G; Jacobs, P; Jones, P G; Kadija, K; Kolesnikov, V I; Kollegger, T; Kowalski, M; Kraus, I; Kreps, M; Lasiuk, B; Van Leeuwen, M; Lévai, Peter; Malakhov, A I; Margetis, S; Markert, C; Mayes, B W; Melkumov, G L; Mischke, A; Molnár, J; Nelson, J M; Odyniec, Grazyna Janina; Oldenburg, M; Pálla, G; Panagiotou, A D; Perl, K; Petridis, A; Pikna, M; Pinsky, L; Poskanzer, A M; Prindle, D J; Pühlhofer, F; Putschke, J; Reid, J G; Renfordt, A; Retyk, W; Ritter, H G; Röhrich, D; Roland, C; Roland, G; Rybicki, A; Sammer, T; Sann, H; Schäfer, E; Schmitz, N; Seyboth, P; Siklér, F; Sitár, B; Skrzypczak, E; Snellings, R; Squier, G T A; Stock, Reinhard; Ströbele, H; Susa, T; Szentpétery, I; Sziklai, J; Toy, M; Trainor, T A; Trentalange, S; Ullrich, T S; Varga, D; Vassiliou, Maria; Veres, G I; Vesztergombi, G; Voloshin, S A; Vranic, D; Wang, F; Weerasundara, D D; Wenig, S; Wetzler, A; Whitten, C; Xu, N; Yates, T A; Koo, I K; Zaranek, J; Zimányi, J

    2002-01-01

    Recent results of the NA49 experiment are presented. These cover first results on pion and kaon production, HBT, and charge fluctuations from Pb+Pb reactions at 40 AGeV and their comparison to 158 AGeV beam energy. Furthermore a study on baryon number transfer in p+p, centrality selected p+Pb and Pb+Pb collisions at 158 AGeV and new results on the system size dependence of kaon yields, including C+C and Si+Si data, are presented. Additionally, a first result on Lambda Lambda correlations is shown. (11 refs).

  4. Loucura imperial na Roma antiga

    Directory of Open Access Journals (Sweden)

    Aloys Winterling

    2012-06-01

    Full Text Available Este artigo aborda a questão da "loucura imperial" na Roma antiga, indagando-se sobre o que seria peculiar a ações de imperadores, como Calígula, Nero e Domiciano, que conduziu a conflitos com a aristocracia. Argumenta-se que apenas uma análise das estruturas e sistemas históricos do Alto Império possibilita explicar certos padrões de comportamento imperial, usualmente classificados como loucura pela historiografia dos séculos XIX e XX.

  5. The effect of Na vapor on the Na content of chondrules

    Science.gov (United States)

    Lewis, R. Dean; Lofgren, Gary E.; Franzen, Hugo F.; Windom, Kenneth E.

    1993-01-01

    Chondrules contain higher concentrations of volatiles (Na) than expected for melt droplets in the solar nebula. Recent studies have proposed that chondrules may have formed under non-canonical nebular conditions such as in particle/gas-rich clumps. Such chondrule formation areas may have contained significant Na vapor. To test the hypothesis of whether a Na-rich vapor would minimize Na volatilization reaction rates in a chondrule analog and maintain the Na value of the melt, experiments were designed where a Na-rich vapor could be maintained around the sample. A starting material with a melting point lower that typical chondrules was required to keep the logistics of working with Na volatilization from NaCl within the realm of feasibility. The Knippa basalt, a MgO-rich alkali olivine basalt with a melting temperature of 1325 +/- 5 C and a Na2O content of 3.05 wt%, was used as the chondrule analog. Experiments were conducted in a 1 atm, gas-mixing furnace with the fO2 controlled by a CO/CO2 gas mixture and fixed at the I-W buffer curve. To determine the extent of Na loss from the sample, initial experiments were conducted at high temperatures (1300 C - 1350 C) for duration of up to 72 h without a Na-rich vapor present. Almost all (up to 98%) Na was volatilized in runs of 72 h. Subsequent trials were conducted at 1330 C for 16 h in the presence of a Na-rich vapor, supplied by a NaCl-filled crucible placed in the bottom of the furnace. Succeeding Knudsen cell weight-loss mass-spectrometry analysis of NaCl determined the P(sub Na) for these experimental conditions to be in the 10(exp -6) atm range. This value is considered high for nebula conditions but is still plausible for non-canonical environments. In these trials the Na2O content of the glass was maintained or in some cases increased; Na2O values ranged from 2.62% wt to 4.37% wt. The Na content of chondrules may be controlled by the Na vapor pressure in the chondrule formation region. Most heating events capable

  6. O ATLETISMO NA PERSPECTIVA EDUCACIONAL

    Directory of Open Access Journals (Sweden)

    Leandro Araujo de Sousa

    2017-06-01

    Full Text Available A educação física escolar deve proporcionar experiências aos alunos para o seu desenvolvimento integral. As aulas muitas vezes são reduzidas ao ensino de esportes tradicionais, o que limita o repertório de movimentos dos alunos. Dessa forma o presente estudo de revisão objetiva problematizar o atletismo no ambiente escolar e propor possibilidades pedagógicas para seu ensino. Nesta pesquisa propomos tratar o ensino do atletismo na escola, caracterizando-o pelo seu repertório de movimentos que são naturais ao ser humano, como correr, saltar e lançar, o que possibilita maior praticidade em sua aplicação pedagógica, porém essas possibilidades não são consideradas no ambiente educacional. Diante dos dados encontrados, sugerimos que esse esporte seja abordado de forma multidimensional no ambiente escolar contextualizando-o à visão de algumas correntes teóricas. Nessa perspectiva do esporte educacional, o atletismo pode, assim como deve ser trabalhado nas aulas de educação física como instrumento pedagógico de ensino e auxiliar na formação do aluno de forma global.

  7. Identidades Homossexuais na Territorialidade Tradicionalista

    Directory of Open Access Journals (Sweden)

    Edipo Djavan dos Reis Göergen

    2015-12-01

    Full Text Available Este artigo apresenta o debate teórico que sustenta a pesquisa de mestrado desenvolvida pelo autor. Tendo por base suas vivências em contextos de tradicionalismo gaúcho, o autor deste trabalho tem percebido a grande quantidade de homossexuais, ou indivíduos que se auto-denominam não-heterossexuais, integrando as atividades artísticas do Movimento Tradicionalista Gaúcho, ou a territorialidade tradicionalista. Interessado em investigar tal fenômeno, o autor tem desenvolvido o projeto de pesquisa “Os Espaços Paradoxais de Relações Homoeróticas na Territorialidade Tradicionalista”, sob orientação do prof. Dr. Benhur Pinós da Costa, no Programa de Pós-Graduação em Geografia (UFSM. Para que essa pesquisa seja realizada, levam-se em conta as relações de gênero e de sexualidade que estão envolvidas no tema. Dessa forma, por ainda se tratarem de temáticas tidas como insignificantes na sociedade em geral e marginalizadas no campo científico, para que o presente trabalho fosse empreendido, buscou-se amparo teórico nas geografias feministas e queer, segmentos contemporâneos da ciência geográfica.

  8. Relationship between intracellular Na+ concentration and reduced Na+ affinity in Na+,K+-ATPase mutants causing neurological disease

    DEFF Research Database (Denmark)

    Toustrup-Jensen, Mads Schak; Einholm, Anja P.; Schack, Vivien

    The neurological disorders familial hemiplegic migraine type 2 (FHM2), alternating hemiplegia of childhood (AHC), and rapid-onset dystonia parkinsonism (RDP) are caused by mutations of Na+,K+-ATPase α2 and α3 isoforms, expressed in glial and neuronal cells, respectively. Although these disorders......, addressing the question to what extent they cause a change of the intracellular Na+ and K+ concentrations ([Na+]i and [K+]i) in COS cells. C-terminal extension mutants generally showed dramatically reduced Na+ affinity without disturbance of K+ binding, as did other RDP mutants. No phosphorylation from ATP...

  9. Fotografia na Imprensa: conflitos na câmara escura

    Directory of Open Access Journals (Sweden)

    José Lúcio da Silva Menezes

    2014-07-01

    Full Text Available Este artigo recupera o teor ideológico do discurso que a Revista Veja elaborou sobre a classe trabalhadora que emergiu no cenário brasileiro, no final da década de 1970. O destaque dado aos trabalhadores como temática central resgatada, deve-se aos movimentos grevistas por eles encetados, após anos de ocultamento de sua resistência sob a repressão da ditadura civil-militar (1964-1985. Com a rebeldia operária, as matérias a respeito deste grupo, na Revista,foram se tornando mais constantes e visíveis, pois já não era mais possível, para a Revista Veja, ignorar a existência da classe operária que, com a força insurgente das greves, ocupava as ruas do Brasil.

  10. Uso da papaína na úlcera plantar

    OpenAIRE

    Otuka, Elizabet Shizue; Pedrazzani, Elisete Silva; Pioto, Mariangela Pedroso

    1996-01-01

    Este trabalho teve por objetivo contribuir para a diminuição da incapacidade em hanseníase e as contínuas recidivas de úceras plantares, através da utilização de um método de tratamento com o uso da papaína e ações de educação em saúde. Foi realizado em um Centro de Saúde com pacientes que apresentavam úcera plantar e que concordaram em participar do tratamento proposto. Analisando e comparando os dados obtidos antes e após o tratamento, concluímos que durante o tratamento foi observada uma m...

  11. Na and K dependence of the Na/K pump in cystic fibrosis fibroblasts.

    OpenAIRE

    Reznik, V M; Schneider, J A; Mendoza, S A

    1981-01-01

    The Na and K dependence of the Na/K pump was measured in skin fibroblasts from patients with cystic fibrosis and age/sex-matched controls. Under basal conditions, there was no difference between control and cystic fibrosis cells in protein per cell, intracellular Na and K content, or Na/K pump activity (measured as ouabain-sensitive 86Rb uptake). There was no difference in the Na dependence of the Na/K pump between cystic fibrosis cells and control cells. In cells from patients with cystic fi...

  12. Vpliv toplotnih mostov na porabo energije za ogrevanje na primeru osnovne šole

    OpenAIRE

    Megušar, Primož

    2015-01-01

    Na primeru Osnovne šole Dobrova sem preveril, kakšen vpliv imajo dejanski toplotni mostovi na porabo energije za ogrevanje. Iz načrtov stavbe sem evidentiral vse toplotne mostove, kateri vplivajo na porabo energije. Tem toplotnim mostovom sem nato v standardu SIST EN ISO 14683 poiskal ustrezne približke. Nato sem s programom TOST izvedel tri simulacije. V prvem primeru toplotnih mostov nisem upošteval. V drugem primeru sem toplotne mostove upošteval na poenostavljen način, v zadnjem primeru p...

  13. Low-spin states of 23Na

    International Nuclear Information System (INIS)

    Bakkum, E.L.

    1987-01-01

    A study of 23 Na via the 22 Ne(p,γ) 23 Na and 23 Na(γ,γ) 23 Na reactions is presented. Only a limited number of resonances has been studied, selected on the basis of strong excitation of the lowest levels of which the spin was unknown. As a result the spins are now known of all levels of 23 Na with excitation energies up to 7 MeV, except for a few high-spin states which are too weakly excited in the decay of the known 22 Ne(p,γ) resonances. The mean lifetimes of the 23 Na levels at 4.43 and 7.89 MeV were found to be 350±70 and 220±17 attoseconds (1 attosecond = 10 -18 seconds) respectively. 97 refs.; 22 figs.; 12 tabs

  14. PRIMERJAVA GEODETSKIH METOD NA ZAHTEVNEM GRADBENEM OBJEKTU

    OpenAIRE

    Reberčnik, Matic

    2017-01-01

    V projektni nalogi smo v uvodnih poglavjih predstavili različne načine izvajanja geodetskih meritev, ki jih v gradbeništvu uporabljamo pri analizi pomikov in deformacij gradbenih konstrukcij ter terena, na katerem so le-te postavljene. V nadaljevanju opisujemo terestične in GNSS (globalni navigacijski satelitski sistem) metode, ki smo jih uporabljali pri izvajanju meritev na izbranem premostitvenem objektu avtocestnega odseka v Sloveniji (zaradi varovanja podatkov ga imenujemo Objekt 1). Pod...

  15. Pioneering instrumentation aspects of NA60

    International Nuclear Information System (INIS)

    David, Andre

    2004-01-01

    NA60 is taking data with proton and heavy-ion beams at the CERN SPS. Although building up on previous experiments, the dimuon physics programme of NA60 places very demanding requirements on its new detectors, in terms of radiation tolerance, granularity and read-out electronics speed. We start by comparing dimuon detection strategies in NA60 with those of previous experiments. We then describe the new detectors used in NA60, placing particular emphasis on their technological pioneering aspects as well as on their contributions to the overall physics performance of the experiment

  16. Fabrication of implanted $^{22}$Na targets

    CERN Multimedia

    2002-01-01

    A knowledge of the $^{22}$Na(p,$\\gamma$)$^{23}$ Mg reaction rate is of significant astrophysical interest. In order to complete previous studies of this reaction, radioactive $^{22}$Na targets of high purity are required. We ask for support to fabricate these targets via the implantation technique at ISOLDE GPS (off—line mode) using $^{22}$Na nuclides in an Al matrix produced in Nov. 1990 at the PSI (Zürich). The $^{22}$Na nuclides are released and ionized in a surface ionisation source, mass-analyzed at ISOLDE GPS, and implanted in a Ni-Ta backing and a C—foil in a special implantation setup.

  17. OGLAŠEVANJE NA FACEBOOKU V SLOVENIJI

    OpenAIRE

    Dobnik, Monja

    2013-01-01

    Danes so zahvaljujoč napredni mobilni tehnologiji družbena omrežja z nami na vsakem koraku. Facebook (FB) se po priljubljenosti uvršča v sam vrh družbenih omrežij in glede na to, da ga uporablja že več kot milijarda zemljanov, ponuja tudi odlične trg za oglaševanje. To so ugotovili tudi slovenski podjetniki. V diplomski nalogi je predstavljeno, kako na FB oglašujejo nekatera slovenska podjetja, s pomočjo spletnega vprašalnika pa je ugotovljeno tudi, kaj o oglasih na FB menijo njegovi uporabni...

  18. Entrada vocabular na linguagem virtual

    OpenAIRE

    Macedo, Valdete Aparecida Xavier de [UNESP

    2002-01-01

    O objetivo deste trabalho foi o de fazer um estudo sobre a projeção do inglês, língua universal, sobre a portuguesa, considerando-se os empréstimos lexicais, porta de entrada para a configuração e enriquecimento vocabular da língua de chegada. Estes vocábulos são indicativos ao vocabulário da língua de especialidade, divulgados nos programas da Internet. Fizemos uma pequena reflexão sobre o fenômeno da linguagem virtual, que vem se cristalizando em discurso interativo de povos e nações coloca...

  19. Zbigniew Herbert, Znaki na papierze

    Directory of Open Access Journals (Sweden)

    Thibault Deleixhe

    2008-10-01

    Full Text Available Dans une interview, Zbigniew Herbert confiait : « Mon travail préparatoire à un livre, ce sont avant tout des dessins. Je ne fais pas de photos, cela simplifierait mon contact avec l’objet. » Il n’en fallait pas moins pour donner aux éditions Bosz l’envie d’un projet : réunir ces précieuses esquisses de travail et les confronter aux textes qui en sont nés. Le résultat s’intitule Znaki na papierze (Signes sur papier et appartient aux objets que l’on est fier de posséder dans sa bibliothèque. ...

  20. O consumo na vida digital

    Directory of Open Access Journals (Sweden)

    Iuri Yudi Furukita Baptista

    2016-02-01

    Full Text Available O modelo de consumo não possui as mesmas características sempre: suas relações, motivações, formatos, espaços, interesses e atividades são construções sociais que se modificam atreladas ao cenário econômico, político e tecnológico. O presente trabalho repassa o surgimento da sociedade do consumidor para então conjecturar sobre as propriedades distintivas do consumo na vida digital. O que se defende ao final é que o consumidor já não se restringe ao papel de consumir.

  1. Odpowiedź na pytanie

    Directory of Open Access Journals (Sweden)

    Michel Foucault

    2016-12-01

    Full Text Available Prezentowany artykuł Michela Foucaulta został opublikowany w 1963 roku. Foucault rozwija w nim koncepcję archeologii wiedzy – metody analizy historycznych dyskursów, którą zaprezentuje w sześć lat później w książce o tym właśnie tytule. Artykuł powstał na kanwie pytania wybranego przez autora spośród zadanych mu przez redakcję „Esprit”, które dotyczyło możliwości pojęciowego opracowania przymusu systemu dyskursywnego przy jednoczesnym zaakcentowaniu nieciągłości w jego obrębie a tym samym możliwości twórczego działania w historii ducha. A także, czy tak sformułowana aporia zakładałaby z konieczności zgodę na przymus systemu lub afirmację siły zdolnej do przekształcenia go za pomocą zewnętrznej przemocy? Tekst jest wprawką do sformułowania dojrzałej teorii dyskursu, rodzajem autoanalizy, która pozwala Foucaultowi powiązać własną metodę historyczną z „progresywistyczną polityką” myśli i rozwiązać w ten sposób dylemat pełnej determinacji i wolnego sprawstwa obecny w rozważaniach wielu strukturalistów.

  2. Na+/Ca2+ exchange and Na+/K+-ATPase in the heart

    Science.gov (United States)

    Shattock, Michael J; Ottolia, Michela; Bers, Donald M; Blaustein, Mordecai P; Boguslavskyi, Andrii; Bossuyt, Julie; Bridge, John H B; Chen-Izu, Ye; Clancy, Colleen E; Edwards, Andrew; Goldhaber, Joshua; Kaplan, Jack; Lingrel, Jerry B; Pavlovic, Davor; Philipson, Kenneth; Sipido, Karin R; Xie, Zi-Jian

    2015-01-01

    This paper is the third in a series of reviews published in this issue resulting from the University of California Davis Cardiovascular Symposium 2014: Systems approach to understanding cardiac excitation–contraction coupling and arrhythmias: Na+ channel and Na+ transport. The goal of the symposium was to bring together experts in the field to discuss points of consensus and controversy on the topic of sodium in the heart. The present review focuses on cardiac Na+/Ca2+ exchange (NCX) and Na+/K+-ATPase (NKA). While the relevance of Ca2+ homeostasis in cardiac function has been extensively investigated, the role of Na+ regulation in shaping heart function is often overlooked. Small changes in the cytoplasmic Na+ content have multiple effects on the heart by influencing intracellular Ca2+ and pH levels thereby modulating heart contractility. Therefore it is essential for heart cells to maintain Na+ homeostasis. Among the proteins that accomplish this task are the Na+/Ca2+ exchanger (NCX) and the Na+/K+ pump (NKA). By transporting three Na+ ions into the cytoplasm in exchange for one Ca2+ moved out, NCX is one of the main Na+ influx mechanisms in cardiomyocytes. Acting in the opposite direction, NKA moves Na+ ions from the cytoplasm to the extracellular space against their gradient by utilizing the energy released from ATP hydrolysis. A fine balance between these two processes controls the net amount of intracellular Na+ and aberrations in either of these two systems can have a large impact on cardiac contractility. Due to the relevant role of these two proteins in Na+ homeostasis, the emphasis of this review is on recent developments regarding the cardiac Na+/Ca2+ exchanger (NCX1) and Na+/K+ pump and the controversies that still persist in the field. PMID:25772291

  3. Kinetin Reversal of NaCl Effects

    Science.gov (United States)

    Katz, Adriana; Dehan, Klara; Itai, Chanan

    1978-01-01

    Leaf discs of Nicotiana rustica L. were floated on NaCl in the presence of kinetin or abscisic acid. On the 5th day 14CO2 fixation, [3H]leucine incorporation, stomatal conductance, and chlorophyll content were determined. Kinetin either partially or completely reversed the inhibitory effects of NaCl while ABA had no effect. PMID:16660618

  4. Silicene for Na-ion battery applications

    KAUST Repository

    Zhu, Jiajie; Schwingenschlö gl, Udo

    2016-01-01

    Na-ion batteries are promising candidates to replace Li-ion batteries in large scale applications because of the advantages in natural abundance and cost of Na. Silicene has potential as the anode in Li-ion batteries but so far has not received

  5. Negative electrodes for Na-ion batteries.

    Science.gov (United States)

    Dahbi, Mouad; Yabuuchi, Naoaki; Kubota, Kei; Tokiwa, Kazuyasu; Komaba, Shinichi

    2014-08-07

    Research interest in Na-ion batteries has increased rapidly because of the environmental friendliness of sodium compared to lithium. Throughout this Perspective paper, we report and review recent scientific advances in the field of negative electrode materials used for Na-ion batteries. This paper sheds light on negative electrode materials for Na-ion batteries: carbonaceous materials, oxides/phosphates (as sodium insertion materials), sodium alloy/compounds and so on. These electrode materials have different reaction mechanisms for electrochemical sodiation/desodiation processes. Moreover, not only sodiation-active materials but also binders, current collectors, electrolytes and electrode/electrolyte interphase and its stabilization are essential for long cycle life Na-ion batteries. This paper also addresses the prospect of Na-ion batteries as low-cost and long-life batteries with relatively high-energy density as their potential competitive edge over the commercialized Li-ion batteries.

  6. Razvitak naselja na kvarnerskim otocima - primjer Dobrinja

    Directory of Open Access Journals (Sweden)

    Marijan Bradanović

    2012-12-01

    Full Text Available Na dosad slabo poznatom i sa stajališta povijesti umjetnosti još posve neobrađenom primjeru Dobrinja na otoku Krku, raspravlja se o razvitku naselja na kvarnerskim otocima. Uz isticanje štetnosti dosad prevladavajućih uopćavanja, karakteristični položaj i razvitak Dobrinja tumače se u širem, komparativnom kontekstu. Analiziraju se prostiranje i obilježja pojedinih dijelova ovog naselja, a naglasak je na vremenu kasnog srednjeg i ranijeg novog vijeka. Tada je najuži dio povijesnog središta Dobrinja poprimio čvrstu, na tlorisnoj osnovi i danas, usprkos opsežnim pregradnjama i arhitektonskim preinakama, jasno uočljivu, urbanu fizionomiju.

  7. Bullying na Escola: um sofrimento

    Directory of Open Access Journals (Sweden)

    Marlene Silva Sardinha Gurpilhares

    2014-07-01

    Full Text Available O bullying é uma forma de violência presente nas escolas e o termo é utilizado para caracterizar todas as formas de agressões repetitivas psicológicas e físicas, direta ou indiretamente. Esta violência causa sofrimentos, intimidação e medo, sempre numa relação de poder entre pares. Esta pesquisa trata de um estudo do bullying escolar: o que é, como surgiu, como identificá-lo e sua caracterização, conseqüências, causas, o papel da escola, de professores e pais e uma proposta prática que pode ser adotada para sua prevenção e contenção. O objetivo é organizar materiais para leitura dos atores educacionais para uma possível reflexão, através de pesquisas bibliográficas. Esta violência é grave e deveria ser tratada como saúde pública, devido às conseqüências que traz, como queda na aprendizagem, na autoestima e em casos mais graves, até o suicido e outras tragédias. A escola necessita atentar para esse tipo de violência, revendo suas ações em todos os momentos, tendo um olhar integral e diferenciado em relação aos alunos. É fundamental que o bullying não seja tratado como brincadeira de criança e para ser identificado e combatido é necessária uma ação entre a família e todos da escola, que pode ser desenvolvida através de projetos que ajudem a apontar caminhos para a solução do problema. Tais ações devem ser pautadas por constantes debates e reflexões, nas quais o aluno se torne o protagonista. Não existem fórmulas prontas, pois a intervenção deve ser feita através da realidade de cada escola.

  8. Study of the Na-C-O and Na-H-O ternary systems in the sodium rich corner

    International Nuclear Information System (INIS)

    Maupre, J.-P.

    1978-02-01

    The purpose of this study is to provide a contribution to the understanding of the sodium - carbon - oxygen and sodium - hydrogen - oxygen ternary systems in the sodium rich corner. In order to do this the Na-NaH-Na 2 O-NaOH phase diagram was completed and the Na-Na 2 O-Na 2 CO 3 -C phase diagram was outlined. This work is made up of two parts. The first is devoted to a critical literature survey essential to establish correct phase diagrams. The second is an experimental study followed by a discussion collating our finding to the literary data. The basic experimental technique used is differential thermal analysis (DTA) but it has been completed by quenching, X-ray and chemical analysis methods. The proposed phase diagrams imply that Na-NaH-Na 2 O-NaOH and Na-Na 2 O-Na 2 CO 3 -C systems are reciprocal ternary systems. Temperatures of stable pairs reversal are respectively 410 and 690 0 C. The stable pairs are Na-NaOH and Na-Na 2 CO 3 at elevated temperature, Na 2 O-NaH and Na 2 O-C at low temperature [fr

  9. OGLAŠEVANJE NA DRUŽBENIH OMREŽJIH NA PRIMERU FACEBOOKA

    OpenAIRE

    Novak, Martina

    2012-01-01

    V diplomskem delu obravnavamo družbene medije kot novo priložnost za promocijo in oglaševanje podjetij. Spoznali smo družbena omrežja na splošno in nekaj teh, ki jih uporabljamo tudi v Sloveniji na kratko predstavili. Podrobneje smo se osredotočili na družbeno omrežje Facebook, predvsem na samo spletno stran, njen izgled in storitve, ki jih ponuja uporabnikom. V nalogi je podrobneje opisan Facebook kot orodje za uporabo oglaševanja. Spoznali smo brezplačne in plačljive načine promocije in ogl...

  10. Terapia de linguagem na afasia

    Directory of Open Access Journals (Sweden)

    Mauro Spinelli

    1977-12-01

    Full Text Available A terapia da linguagem na afasia foi estudada em 15 pacientes, 8 do sexo masculino e 7 do sexo feminino; a idade variou de menos de 10 anos a mais de 50 anos; em 11 casos a afasia era sequela de acidente vascular cerebral e, em 4, de traumatismo crânio-encefálico. Quanto ao tipo de afasia, 5 pacientes apresentavam déficits predominantemente de expressão e 10 apresentavam déficits receptivos e expressivos em graus equiparáveis. Em 6 casos a terapia foi iniciada dentro dos 3 primeiros meses de instalação do quadro; nos restantes foi iniciada mais tardiamente. Dos 15 pacientes, 11 apresentaram evolução satisfatória, a qual não depndeu do grau de afasia, do tipo de afasia, da idade do paciente, do tipo de patologia e do intervalo entre a instalação do quadro afásico e o início da terapia. A terapia da linguagem no paciente afásico é efetiva, o prognóstico não pode ser feito a priori. Somente a evolução do caso com sua retestagem criteriosa poderá dar dados realmente úteis para se falar em evolução.

  11. Extracellular Na+ levels regulate formation and activity of the NaX/alpha1-Na+/K+-ATPase complex in neuronal cells.

    Directory of Open Access Journals (Sweden)

    Emmanuelle eBerret

    2014-12-01

    Full Text Available MnPO neurons play a critical role in hydromineral homeostasis regulation by acting as sensors of extracellular sodium concentration ([Na+]out. The mechanism underlying Na+-sensing involves Na+-flow through the NaX channel, directly regulated by the Na+/K+-ATPase α1-isoform which controls Na+-influx by modulating channel permeability. Together, these two partners form a complex involved in the regulation of intracellular sodium ([Na+]in. Here we aim to determine whether environmental changes in Na+ could actively modulate the NaX/Na+/K+-ATPase complex activity.We investigated the complex activity using patch-clamp recordings from rat MnPO neurons and Neuro2a cells. When the rats were fed with a high-salt-diet, or the [Na+] in the culture medium was increased, the activity of the complex was up-regulated. In contrast, drop in environmental [Na+] decreased the activity of the complex. Interestingly under hypernatremic condition, the colocalization rate and protein level of both partners were up-regulated. Under hyponatremic condition, only NaX protein expression was increased and the level of NaX/Na+/K+-ATPase remained unaltered. This unbalance between NaX and Na+/K+-ATPase pump proportion would induce a bigger portion of Na+/K+-ATPase-control-free NaX channel. Thus we suggest that hypernatremic environment increases NaX/Na+/K+-ATPase α1-isoform activity by increasing the number of both partners and their colocalization rate, whereas hyponatremic environment down-regulates complex activity via a decrease in the relative number of NaX channels controlled by the pump.

  12. Artesanato na terceira idade: um estudo na cidade de Sinop

    Directory of Open Access Journals (Sweden)

    Rosane Marlene Weber

    2012-06-01

    Full Text Available O presente artigo sobre o artesanato e a Terceira Idade, pesquisa realizada em 2011, teve como metodologia o Estudo de Caso do tipo etnográfico. A metodologia de investigação ocorreu por meio de entrevistas semiestruturadas, orais e transcritas, observação e fotografias dos artesanatos em locais de venda e nas residências dos artesãos. Os sujeitos da pesquisa foram: a presidente da Associação da Casa do Artesão de Sinop-MT e oito artesãos. O objetivo foi mostrar a importância do artesanato como atividade educacional e como produtora de autonomia e autoria para os artesãos da Terceira Idade, motivados em realizar este trabalho nesta fase da vida. Para o embasamento teórico utilizou-se obras de Paulo Freire, Moacir Gadotti e sobre a Terceira Idade a coleção de Vivaidade com a organizadora Anita Liberalesso Neri. A análise das entrevistas mostrou que o artesanato traz autonomia educacional quando o idoso busca sozinho aprender sobre o objeto a ser realizado, assim como autonomia financeira, uma vez que a venda do artesanato proporciona certa independência econômica. Em relação ao sentimento de autoria das peças criadas constatou-se muita satisfação e realização, o que motiva a continuar sendo úteis e produtivos na Terceira Idade com muita criatividade. Palavras-chave: educação; terceira idade; artesanato; autonomia; autoria.

  13. Glutamate Water Gates in the Ion Binding Pocket of Na(+) Bound Na(+), K(+)-ATPase

    DEFF Research Database (Denmark)

    Han, Minwoo; Kopec, Wojciech; Solov'yov, Ilia A

    2017-01-01

    III is always protonated. Glutamic acid residues in the three binding sites act as water gates, and their deprotonation triggers water entry to the binding sites. From DFT calculations of Na(+) binding energies, we conclude that three protons in the binding site are needed to effectively bind Na......The dynamically changing protonation states of the six acidic amino acid residues in the ion binding pocket of the Na(+), K(+) -ATPase (NKA) during the ion transport cycle are proposed to drive ion binding, release and possibly determine Na(+) or K(+) selectivity. We use molecular dynamics (MD......(+) from water and four are needed to release them in the next step. Protonation of Asp926 in site III will induce Na(+) release, and Glu327, Glu954 and Glu779 are all likely to be protonated in the Na(+) bound occluded conformation. Our data provides key insights into the role of protons in the Na...

  14. Crystal structure of Na+, K(+)-ATPase in the Na(+)-bound state.

    Science.gov (United States)

    Nyblom, Maria; Poulsen, Hanne; Gourdon, Pontus; Reinhard, Linda; Andersson, Magnus; Lindahl, Erik; Fedosova, Natalya; Nissen, Poul

    2013-10-04

    The Na(+), K(+)-adenosine triphosphatase (ATPase) maintains the electrochemical gradients of Na(+) and K(+) across the plasma membrane--a prerequisite for electrical excitability and secondary transport. Hitherto, structural information has been limited to K(+)-bound or ouabain-blocked forms. We present the crystal structure of a Na(+)-bound Na(+), K(+)-ATPase as determined at 4.3 Å resolution. Compared with the K(+)-bound form, large conformational changes are observed in the α subunit whereas the β and γ subunit structures are maintained. The locations of the three Na(+) sites are indicated with the unique site III at the recently suggested IIIb, as further supported by electrophysiological studies on leak currents. Extracellular release of the third Na(+) from IIIb through IIIa, followed by exchange of Na(+) for K(+) at sites I and II, is suggested.

  15. Laser-induced ionization of Na vapor

    International Nuclear Information System (INIS)

    Wu, R.C.Y.; Judge, D.L.; Roussel, F.; Carre, B.; Breger, P.; Spiess, G.

    1982-01-01

    The production of Na 2 + ions by off-resonant laser excitation in the 5800-6200A region mainly results from two-photon absorption by the Na 2 molecule to highly excited gerade states followed by (a) direct ionization by absorbing a third photon or (b) coupling to the molecular Na 2 D 1 PIμ Rydberg state which is subsequently ionized by absorbing a third photon. This mechanism, i.e., a two-photon resonance three photon ionization process, explains a recent experimental observation of Roussel et al. It is suggested that the very same mechanism is also responsible for a similar observation reported by Polak-Dingels et al in their work using two crossed Na beams. In the latter two studies the laser-induced associative ionization processes were reported to be responsible for producing the Na 2 + ion. From the ratio of molecular to atomic concentration in the crossed beam experiment of Polak-Dingels et al we estimate that the cross section for producing Na 2 + through laser-induced associative ionization is at least four orders of magnitude smaller than ionization through the two-photon resonance three photon ionization process in Na 2 molecules

  16. NaK handling and removal

    International Nuclear Information System (INIS)

    Desreumaux, J.; Rodriguez, G.; Guigon, A.; Verdelli, J.; Thomine, G.

    1997-01-01

    Sodium-potassium alloy is used in specific application in French Fast Breeder Reactors as: cold traps, NaK bubbler for argon purification, valves and also in experimental irradiation devices. lt has been preferred to sodium because it is liquid from + 7 deg. C for the most common peritectic alloy. After its use, NaK is considered as a hazardous waste (nuclear or not) due to its high reactivity with air and water. The most important risk remains in handling NaK systems which have not been operated for some time. The NaK will be covered with a crust of the superoxide K02 which is a strong oxidising agent. Thermodynamically, K02 will react with most organic material or metallic dust or swarfs and can also react with additional NaK to give sufficient heat to boil part of the NaK, resulting in a sudden increase in pressure and small explosions. We describe the formation given to experimenters in our Sodium School and the CEA's experience in treating specific devices for transportation, decanting of tanks, tank opening and NaK removal. (author)

  17. Evolução de uma criança com sindrome de Down à luz do modelo lúdico: estudo de caso / Evolution of a child with Down’s syndrome according to the ludic model: case study

    Directory of Open Access Journals (Sweden)

    Tatyane Soriano Gonçalves Diniz da Silva

    2018-01-01

    Full Text Available Introdução: O brincar é fundamental para o desenvolvimento da criança. Brincando ela desenvolve os sentidos, adquire habilidades, amplia suas experiências e descobertas, e potencializa a criatividade, a inteligência e a sociabilidade. Na clínica de Terapia Ocupacional, o brincar é visto como um recurso terapêutico e uma ocupação fundamental na vida da criança, podendo ser avaliado a partir do referencial teórico do Modelo Lúdico. Objetivo: Analisar a evolução do comportamento lúdico e a percepção da família sobre o desenvolvimento de uma criança de 2 anos e 5 meses, com síndrome de Down, que foi acompanhada pela Terapia Ocupacional, em uma brinquedoteca terapêutica por 18 meses. Método: Estudo com abordagem qualitativa e quantitativa, realizado com o auxílio da Avaliação do Comportamento Lúdico, Entrevista Inicial com os Pais, Ficha de Avaliação do Serviço de Terapia Ocupacional e evoluções dos atendimentos. Resultados: Os dados mostraram evolução do interesse geral e lúdico, capacidade lúdica e atitude lúdica, mas com menor evolução na habilidade de expressão. Conclusão: Com base no referencial teórico do Modelo Lúdico, foi possível compreender o comportamento lúdico da criança estudada, planejar os atendimentos terapêuticos ocupacionais e avaliar seu desenvolvimento e as contribuições do trabalho realizado na brinquedoteca.

  18. Na/K pump inactivation, subsarcolemmal Na measurements, and cytoplasmic ion turnover kinetics contradict restricted Na spaces in murine cardiac myocytes

    OpenAIRE

    Lu, Fang-Min; Hilgemann, Donald W.

    2017-01-01

    The Na/K pump exports cytoplasmic Na ions while importing K ions, and its activity is thought to be affected by restricted intracellular Na diffusion in cardiac myocytes. Lu and Hilgemann find instead that the pump can enter an inactivated state and that inactivation can be relieved by cytoplasmic Na.

  19. MODELI MERJENJA KAKOVOSTI STORITEV NA MEDORGANIZACIJSKEM TRGU

    OpenAIRE

    Cestnik, Dušan

    2011-01-01

    Vse večja konkurenca na medorganizacijskih trgih sili tako storitvena podjetja, kot tudi podjetja, ki tržijo izdelke, da svoje delo opravljajo vse bolj kakovostno na vseh ravneh svojega delovanja. Podjetja morajo svoje odjemalce obdržati, prav tako pa morajo delovati tudi na pridobivanju novih odjemalcev. Da pa podjetja svoje odjemalce obdržijo morajo nenehno delovati tako, da uživajo zaupanje svojih odjemalcev. Odjemalec že z odločitvijo za neko določeno podjetje XY pričakuje, da bodo storit...

  20. Na+,K+ pumpen vedbliver at overraske

    DEFF Research Database (Denmark)

    Vilsen, Bente

    2008-01-01

    This article provides an overview of news about the Na+,K+ pump, an indispensable enzyme whose protein structure has been described in a recent article in Nature, 50 years after its discovery. In combination with mutational analysis, the structure reveals the binding pocket for the K+ ions...... and the regulation of Na+ transport by a strategically located C-terminus of the protein. Focus is also on the pathophysiology of two neurological disorders, familial hemiplegic migraine and rapid-onset dystonia-parkinsonism, recently shown to be caused by mutations in the Na+,K+-ATPase. Udgivelsesdato: may 19...

  1. Myocardial Na,K-ATPase: Clinical aspects

    Science.gov (United States)

    Kjeldsen, Keld

    2003-01-01

    The specific binding of digitalis glycosides to Na,K-ATPase is used as a tool for Na,K-ATPase quantification with high accuracy and precision. In myocardial biopsies from patients with heart failure, total Na,K-ATPase concentration is decreased by around 40%; a correlation exists between a decrease in heart function and a decrease in Na,K-ATPase concentration. During digitalization, around 30% of remaining pumps are occupied by digoxin. Myocardial Na,K-ATPase is also influenced by other drugs used for the treatment of heart failure. Thus, potassium loss during diuretic therapy has been found to reduce myocardial Na,K-ATPase, whereas angiotensin-converting enzyme inhibitors may stimulate Na,K pump activity. Furthermore, hyperaldosteronism induced by heart failure has been found to decrease Na,K-ATPase activity. Accordingly, treatment with the aldosterone antagonist, spironolactone, may also influence Na,K-ATPase activity. The importance of Na,K pump modulation with heart disease, inhibition in digitalization and other effects of medication should be considered in the context of sodium, potassium and calcium regulation. It is recommended that digoxin be administered to heart failure patients who, after institution of mortality-reducing therapy, still have heart failure symptoms, and that the therapy be continued if symptoms are revealed or reduced. Digitalis glycosides are the only safe inotropic drugs for oral use that improve hemodynamics in heart failure. An important aspect of myocardial Na,K pump affection in heart disease is its influence on extracellular potassium (Ke) homeostasis. Two important aspects should be considered: potassium handling among myocytes, and effects of potassium entering the extracellular space of the heart via the bloodstream. It should be noted that both of these aspects of Ke homeostasis are affected by regulatory aspects, eg, regulation of the Na,K pump by physiological and pathophysiological conditions, as well as by medical

  2. Nalaz tombusvirusa na vrsti Erigeron canadensis L.

    OpenAIRE

    Jeknić, Zoran; Erić, Živojin; Grbelja, Julijana

    1988-01-01

    Iz listova zaraženih primjeraka korovne biljke Erigeron canadensis L. koji su rasli na nekoliko lokaliteta u Sarajevu izoliran je virus iz skupine tombusvirusi. Identifikacija virusa izvršena je na osnovi reakcije pokusnih biljaka, analize ultratankih presjeka kroz zaraženo tkivo, morfologije i veličine virusnih čestica, te na osnovi seroloških reakcija metodom dvostruke imunodifuzije u agarskom gelu i čvrsto fazne imunoelektronske mikroskopije (SPIEM). U serološkim pokusima upotrijebljen je ...

  3. Glutathionylation-Dependence of Na+-K+-Pump Currents Can Mimic Reduced Subsarcolemmal Na+ Diffusion

    Science.gov (United States)

    Garcia, Alvaro; Liu, Chia-Chi; Cornelius, Flemming; Clarke, Ronald J.; Rasmussen, Helge H.

    2016-01-01

    The existence of a subsarcolemmal space with restricted diffusion for Na+ in cardiac myocytes has been inferred from a transient peak electrogenic Na+-K+ pump current beyond steady state on reexposure of myocytes to K+ after a period of exposure to K+-free extracellular solution. The transient peak current is attributed to enhanced electrogenic pumping of Na+ that accumulated in the diffusion-restricted space during pump inhibition in K+-free extracellular solution. However, there are no known physical barriers that account for such restricted Na+ diffusion, and we examined if changes of activity of the Na+-K+ pump itself cause the transient peak current. Reexposure to K+ reproduced a transient current beyond steady state in voltage-clamped ventricular myocytes as reported by others. Persistence of it when the Na+ concentration in patch pipette solutions perfusing the intracellular compartment was high and elimination of it with K+-free pipette solution could not be reconciled with restricted subsarcolemmal Na+ diffusion. The pattern of the transient current early after pump activation was dependent on transmembrane Na+- and K+ concentration gradients suggesting the currents were related to the conformational poise imposed on the pump. We examined if the currents might be accounted for by changes in glutathionylation of the β1 Na+-K+ pump subunit, a reversible oxidative modification that inhibits the pump. Susceptibility of the β1 subunit to glutathionylation depends on the conformational poise of the Na+-K+ pump, and glutathionylation with the pump stabilized in conformations equivalent to those expected to be imposed on voltage-clamped myocytes supported this hypothesis. So did elimination of the transient K+-induced peak Na+-K+ pump current when we included glutaredoxin 1 in patch pipette solutions to reverse glutathionylation. We conclude that transient K+-induced peak Na+-K+ pump current reflects the effect of conformation-dependent β1 pump subunit

  4. Altered Na+ transport after an intracellular alpha-subunit deletion reveals strict external sequential release of Na+ from the Na/K pump.

    Science.gov (United States)

    Yaragatupalli, Siddhartha; Olivera, J Fernando; Gatto, Craig; Artigas, Pablo

    2009-09-08

    The Na/K pump actively exports 3 Na(+) in exchange for 2 K(+) across the plasmalemma of animal cells. As in other P-type ATPases, pump function is more effective when the relative affinity for transported ions is altered as the ion binding sites alternate between opposite sides of the membrane. Deletion of the five C-terminal residues from the alpha-subunit diminishes internal Na(+) (Na(i)(+)) affinity approximately 25-fold [Morth et al. (2007) Nature 450:1043-1049]. Because external Na(+) (Na(o)(+)) binding is voltage-dependent, we studied the reactions involving this process by using two-electrode and inside-out patch voltage clamp in normal and truncated (DeltaKESYY) Xenopus-alpha1 pumps expressed in oocytes. We observed that DeltaKESYY (i) decreased both Na(o)(+) and Na(i)(+) apparent affinities in the absence of K(o)(+), and (ii) did not affect apparent Na(o)(+) affinity at high K(o)(+). These results support a model of strict sequential external release of Na(+) ions, where the Na(+)-exclusive site releases Na(+) before the sites shared with K(+) and the DeltaKESYY deletion only reduces Na(o)(+) affinity at the shared sites. Moreover, at nonsaturating K(o)(+), DeltaKESYY induced an inward flow of Na(+) through Na/K pumps at negative potentials. Guanidinium(+) can also permeate truncated pumps, whereas N-methyl-D-glucamine cannot. Because guanidinium(o)(+) can also traverse normal Na/K pumps in the absence of both Na(o)(+) and K(o)(+) and can also inhibit Na/K pump currents in a Na(+)-like voltage-dependent manner, we conclude that the normal pathway transited by the first externally released Na(+) is large enough to accommodate guanidinium(+).

  5. Possibilidades e desafios na formação de professores de língua inglesa a indivíduos com a Síndrome de Asperger

    OpenAIRE

    Eduardo Pimentel da Rocha

    2016-01-01

    Este trabalho tem o intuito de (re)pensar a formação de professores de inglês (LI), no que tange às suas possibilidades e os seus desafios, por meio da trans-multidisciplinaridade, mais especificamente por meio do referencial teórico da Neuroeducação, e o ensino de LI para aprendizes com a Sindrome de Asperger (SA), tendo como contexto a Universidade Estadual de Londrina (UEL) e as leis de inclusão. Para tanto, dois objetivos foram propostos, a saber: 1) Identificar se e como o curso de licen...

  6. Erythrocyte 22Na+ influx in hypertension

    International Nuclear Information System (INIS)

    Shalev, O.; Eaton, J.W.; Ben-Ishay, D.

    1984-01-01

    We assessed 22Na+ uptake by erythrocytes (RBC) from 38 individuals with essential hypertension and 37 healthy controls. All subjects were male, white, non-obese and with normal renal function, obviating sex, race, hormonal, ponderal and renal factors known to influence RBC Na+ handling. The mean +/- sem 22Na+ uptake of the patients was 284 +/- 16 mumole/liter RBC/hour while that of normal controls was 249 +/- 11 mumole/liter RBC/hour; although the difference reached borderline significance, individual values showed considerable overlap. Consequently, in our population, RBC 22Na+ uptake is not a reliable marker for essential hypertension. We believe that previous studies should be reassessed with regard to patients' characteristics and future studies employ rigorous criteria in selection of subjects

  7. Painful Na-channelopathies: an expanding universe.

    Science.gov (United States)

    Waxman, Stephen G

    2013-07-01

    The universe of painful Na-channelopathies--human disorders caused by mutations in voltage-gated sodium channels--has recently expanded in three dimensions. We now know that mutations of sodium channels cause not only rare genetic 'model disorders' such as inherited erythromelalgia and channelopathy-associated insensitivity to pain but also common painful neuropathies. We have learned that mutations of NaV1.8, as well as mutations of NaV1.7, can cause painful Na-channelopathies. Moreover, recent studies combining atomic level structural models and pharmacogenomics suggest that the goal of genomically guided pain therapy may not be unrealistic. Copyright © 2013 Elsevier Ltd. All rights reserved.

  8. Usmerjanje urbanega razvoja na mestni ravni

    Directory of Open Access Journals (Sweden)

    Mojca Šašek Divjak

    1999-01-01

    Full Text Available Kot je poudarjeno v predstavljenem načrtu Kopenhagna, mestni načrt ne more rešiti vseh planskih problemov mesta. Predstavljal naj bi predvideni red, ki pa se pogosto sproti podira glede na nepredvidena dogajanja v prostoru. Probleme je velikokrat treba reševati šele, ko se pokažejo. Zato mora biti mestni načrt zastavljen dovolj prilagodljivo in fleksibilno, da dovoljuje potrebne spremembe. Vendar mora kljub temu dati mestu trdne glavne usmeritve in s tem omogočiti, da meščani lahko izkoristijo priložnosti, ki jih nudi nova doba in uveljavljajo nove kvalitete bivanja.

  9. Na+-H+ exchange and Na+-dependent transport systems in streptozotocin diabetic rat kidneys

    International Nuclear Information System (INIS)

    El-Seifi, S.; Freiberg, J.M.; Kinsella, F.J.; Cheng, L.; Sacktor, B.

    1987-01-01

    The streptozotocin-induced diabetic rat was used to test the hypothesis that Na + -H + exchange activity in the proximal tubule luminal membrane would be increased in association with renal hypertrophy, altered glomerular hemodynamics, enhanced filtered load and tubular reabsorption of 22 Na + , and stimulated 22 Na= pump activity in the basolateral membrane, previously reported characteristics of this experimental animal model. Amiloride-sensitive H + gradient-dependent Na + uptake and Na + gradient-dependent H + flux were increased in brush-border membrane vesicles from the streptozotocin-treated animals. Na + gradient-dependent uptakes of phosphate, D-glucose, L-proline, and myoinositol were decreased in the drug-induced diabetic animals. These membrane transport alterations were not found when the streptozotocin-diabetic animals were treated with insulin

  10. Effects of EDTA-Na (Na ethylenediaminetetraacetate) upon the metabolism of radiostrontium and radioyttrium in mice

    Energy Technology Data Exchange (ETDEWEB)

    Kikuchi, T; Wakisaka, G; Kono, T; Hiroaki, A; Yamamasu, T; Sugawa, I

    1954-01-01

    The toxicity of EDTA-Na, inert Sr (NO/sub 3/)/sub 2/ and Ba (NO/sub 3/)/sub 2/ has been examined. Simultaneous injection of EDTA-Na showed no significant effect upon the distribution of radio-Sr in the bones of mice. The distribution of radio-Y in the bones of mice tended to decrease following the simultaneous subcutaneous injection of /sup 91/Y and EDTA-Na.

  11. Glutathionylation-Dependence of Na+-K+-Pump Currents Can Mimic Reduced Subsarcolemmal Na+ Diffusion

    OpenAIRE

    Garcia, Alvaro; Liu, Chia-Chi; Cornelius, Flemming; Clarke, Ronald?J.; Rasmussen, Helge?H.

    2016-01-01

    The existence of a subsarcolemmal space with restricted diffusion for Na+ in cardiac myocytes has been inferred from a transient peak electrogenic Na+-K+ pump current beyond steady state on reexposure of myocytes to K+ after a period of exposure to K+-free extracellular solution. The transient peak current is attributed to enhanced electrogenic pumping of Na+ that accumulated in the diffusion-restricted space during pump inhibition in K+-free extracellular solution. However, there are no know...

  12. NA62 and NA48/2 results on search for Heavy Neutral Leptons

    Directory of Open Access Journals (Sweden)

    Lamanna Gianluca

    2018-01-01

    Full Text Available In this paper we present new results on upper limits for the search of Heavy Neutral Leptons (HNL with data collected by NA48/2 (2003-2004, NA62-RK (2007 and NA62 (2015 CERN experiments. The data collected with different trigger configuration allow to search for both long and short living heavy neutrinos in the mass range below the kaon mass. In addition the status of the search for K+ → π+vv with the NA62 detector will be briefly presented.

  13. Interaction between Na+/K+-pump and Na+/Ca2+-exchanger modulates intercellular communication.

    Science.gov (United States)

    Matchkov, Vladimir V; Gustafsson, Helena; Rahman, Awahan; Briggs Boedtkjer, Donna M; Gorintin, Sarah; Hansen, Anne Kirstine; Bouzinova, Elena V; Praetorius, Helle A; Aalkjaer, Christian; Nilsson, Holger

    2007-04-13

    Ouabain, a specific inhibitor of the Na(+)/K(+)-pump, has previously been shown to interfere with intercellular communication. Here we test the hypothesis that the communication between vascular smooth muscle cells is regulated through an interaction between the Na(+)/K(+)-pump and the Na(+)/Ca(2+)-exchanger leading to an increase in the intracellular calcium concentration ([Ca(2+)](i)) in discrete areas near the plasma membrane. [Ca(2+)](i) in smooth muscle cells was imaged in cultured rat aortic smooth muscle cell pairs (A7r5) and in rat mesenteric small artery segments simultaneously with force. In A7r5 coupling between cells was estimated by measuring membrane capacitance. Smooth muscle cells were uncoupled when the Na(+)/K(+)-pump was inhibited either by a low concentration of ouabain, which also caused a localized increase of [Ca(2+)](i) near the membrane, or by ATP depletion. Reduction of Na(+)/K(+)-pump activity by removal of extracellular potassium ([K(+)](o)) also uncoupled cells, but only after inhibition of K(ATP) channels. Inhibition of the Na(+)/Ca(2+)-exchange activity by SEA0400 or by a reduction of the equilibrium potential (making it more negative) also uncoupled the cells. Depletion of intracellular Na(+) and clamping of [Ca(2+)](i) at low concentrations prevented the uncoupling. The experiments suggest that the Na(+)/K(+)-pump may affect gap junction conductivity via localized changes in [Ca(2+)](i) through modulation of Na(+)/Ca(2+)-exchanger activity.

  14. Na5NbO5 and Na5TaO5 phases

    International Nuclear Information System (INIS)

    Darriet, J.; Maazaz, A.; Bouloux, J.C.; Delmas, C.

    1982-01-01

    New ternary oxides of formulas Na 5 NbO 5 and Na 5 TaO 5 have been prepared. They crystallize in the monoclinic system (space group C2/c). The crystal structure of Na 5 NbO 5 has been determined. It derives from a NaCl-type structure by ordering of the cations and of the oxygen vacancies in the anionic sublattice, the corresponding formula being Nasub(5/6)Nbsub(1/6)Osub(5/6)vacant sub(1/6). Sodium and niobium have a distorted square-pyramidal surrounding. (author)

  15. Suppression of Na interstitials in Na-F codoped ZnO

    Science.gov (United States)

    Huo, Wenxing; Mei, Zengxia; Tang, Aihua; Liang, Huili; Du, Xiaolong

    2018-04-01

    Controlling the formation of interstitial Na (Nai) self-compensating defects has been a long-term physics problem for effective Na doping in ZnO. Herein, we present an experimental approach to the suppression of Nai defects in ZnO via Na and F codoping under an oxygen-rich condition during the molecular beam epitaxy growth process. It is found that the incorporation of such large numbers of Na and F dopants (˜1020 cm-3) does not cause an obvious influence on the lattice parameters. Hall-effect measurements demonstrate that F doping efficiently raises the Fermi level (EF) of ZnO films, which is expected to make the formation energy of Nai and NaZn increase and decrease, respectively. Most of the Na atoms occupy the substitutional Zn sites, and the formation of Nai is suppressed consequently. Secondary ion mass spectrometry measurements reveal that F and Na atoms are tightly bonded together due to their strong Coulomb interaction. The enhanced deep level emission (DLE) in ZnO:Na-F is ascribed to the considerable amount of isolated Zn vacancy (VZn) defects induced by the elevated EF and the formation of neutral (" separators="| FO + - Na Zn - ) 0 complexes. On the other hand, formation of (" separators="| FO + - VZn 2 - ) - complexes in ZnO:F exhausts most of the isolated Zn vacancies, leading to the disappearance of the DLE band.

  16. MOŽNOSTI VSTOPA NA TUJE TRGE NA PRIMERU PODJETJA AWOODTURE

    OpenAIRE

    Orličnik, Urša

    2014-01-01

    Danes pojavljanje podjetja samo na domačem trgu ni več dovolj. Spremembe okolja, naraščanje konkurence ter hiter tehnološki napredek, silijo podjetja k nenehnemu prilagajanju in iskanju novih priložnosti tako na domačem kot tudi na tujem trgu. Internacionalizacija podjetja tako postaja vedno bolj pomemembna za preživetje podjetja. Internacionalizacija se v najširšem smislu nanaša na vse oblike mednarodnega ekonomskega sodelovanja. Je dinamičen proces, kateremu nujno sledi sprememba stanja...

  17. Elastic Coulomb breakup of 34Na

    Science.gov (United States)

    Singh, G.; Shubhchintak, Chatterjee, R.

    2016-08-01

    Background: 34Na is conjectured to play an important role in the production of seed nuclei in the alternate r -process paths involving light neutron rich nuclei very near the β -stability line, and as such, it is important to know its ground state properties and structure to calculate rates of the reactions it might be involved in, in the stellar plasma. Found in the region of `island of inversion', its ground state might not be in agreement with normal shell model predictions. Purpose: The aim of this paper is to study the elastic Coulomb breakup of 34Na on 208Pb to give us a core of 33Na with a neutron and in the process we try and investigate the one neutron separation energy and the ground state configuration of 34Na. Method: A fully quantum mechanical Coulomb breakup theory within the architecture of post-form finite range distorted wave Born approximation extended to include the effects of deformation is used to research the elastic Coulomb breakup of 34Na on 208Pb at 100 MeV/u. The triple differential cross section calculated for the breakup is integrated over the desired components to find the total cross-section, momentum, and angular distributions as well as the average momenta, along with the energy-angular distributions. Results: The total one neutron removal cross section is calculated to test the possible ground state configurations of 34Na. The average momentum results along with energy-angular calculations indicate 34Na to have a halo structure. The parallel momentum distributions with narrow full widths at half-maxima signify the same. Conclusion: We have attempted to analyze the possible ground state configurations of 34Na and in congruity with the patterns in the `island of inversion' conclude that even without deformation, 34Na should be a neutron halo with a predominant contribution to its ground state most probably coming from 33Na(3 /2+)⊗ 2 p3 /2ν configuration. We also surmise that it would certainly be useful and rewarding to test our

  18. Clues to NaCN formation

    Science.gov (United States)

    Quintana-Lacaci, G.; Cernicharo, J.; Velilla Prieto, L.; Agúndez, M.; Castro-Carrizo, A.; Fonfría, J. P.; Massalkhi, S.; Pardo, J. R.

    2017-11-01

    Context. ALMA is providing us essential information on where certain molecules form. Observing where these molecules emission arises from, the physical conditions of the gas, and how this relates with the presence of other species allows us to understand the formation of many species, and to significantly improve our knowledge of the chemistry that occurs in the space. Aims: We studied the molecular distribution of NaCN around IRC +10216, a molecule detected previously, but whose origin is not clear. High angular resolution maps allow us to model the abundance distribution of this molecule and check suggested formation paths. Methods: We modeled the emission of NaCN assuming local thermal equilibrium (LTE) conditions. These profiles were fitted to azimuthal averaged intensity profiles to obtain an abundance distribution of NaCN. Results: We found that the presence of NaCN seems compatible with the presence of CN, probably as a result of the photodissociation of HCN, in the inner layers of the ejecta of IRC +10216. However, similar as for CH3CN, current photochemical models fail to reproduce this CN reservoir. We also found that the abundance peak of NaCN appears at a radius of 3 × 1015 cm, approximately where the abundance of NaCl, suggested to be the parent species, starts to decay. However, the abundance ratio shows that the NaCl abundance is lower than that obtained for NaCN. We expect that the LTE assumption might result in NaCN abundances higher than the real ones. Updated photochemical models, collisional rates, and reaction rates are essential to determine the possible paths of the NaCN formation. Based on observations carried out with ALMA and the IRAM 30 m Telescope. ALMA is a partnership of ESO (representing its member states), NSF (USA) and NINS (Japan), together with NRC (Canada) and NSC and ASIAA (Taiwan), in cooperation with the Republic of Chile. The Joint ALMA Observatory is operated by ESO, AUI/NRAO and NAOJ. IRAM is supported by INSU/CNRS (France

  19. HCO3(-)-coupled Na+ influx is a major determinant of Na+ turnover and Na+/K+ pump activity in rat hepatocytes

    International Nuclear Information System (INIS)

    Fitz, J.G.; Lidofsky, S.D.; Weisiger, R.A.; Xie, M.H.; Cochran, M.; Grotmol, T.; Scharschmidt, B.F.

    1991-01-01

    Recent studies in hepatocytes indicate that Na(+)-coupled HCO3- transport contributes importantly to regulation of intracellular pH and membrane HCO3- transport. However, the direction of net coupled Na+ and HCO3- movement and the effect of HCO3- on Na+ turnover and Na+/K+ pump activity are not known. In these studies, the effect of HCO3- on Na+ influx and turnover were measured in primary rat hepatocyte cultures with 22Na+, and [Na+]i was measured in single hepatocytes using the Na(+)-sensitive fluorochrome SBFI. Na+/K+ pump activity was measured in intact perfused rat liver and hepatocyte monolayers as Na(+)-dependent or ouabain-suppressible 86Rb uptake, and was measured in single hepatocytes as the effect of transient pump inhibition by removal of extracellular K+ on membrane potential difference (PD) and [Na+]i. In hepatocyte monolayers, HCO3- increased 22Na+ entry and turnover rates by 50-65%, without measurably altering 22Na+ pool size or cell volume, and HCO3- also increased Na+/K+ pump activity by 70%. In single cells, exposure to HCO3- produced an abrupt and sustained rise in [Na+]i from approximately 8 to 12 mM. Na+/K+ pump activity assessed in single cells by PD excursions during transient K+ removal increased congruent to 2.5-fold in the presence of HCO3-, and the rise in [Na+]i produced by inhibition of the Na+/K+ pump was similarly increased congruent to 2.5-fold in the presence of HCO3-. In intact perfused rat liver, HCO3- increased both Na+/K+ pump activity and O2 consumption. These findings indicate that, in hepatocytes, net coupled Na+ and HCO3- movement is inward and represents a major determinant of Na+ influx and Na+/K+ pump activity. About half of hepatic Na+/K+ pump activity appears dedicated to recycling Na+ entering in conjunction with HCO3- to maintain [Na+]i within the physiologic range

  20. Coulomb excitation of radioactive 20, 21Na

    Science.gov (United States)

    Schumaker, M. A.; Cline, D.; Hackman, G.; Pearson, C.; Svensson, C. E.; Wu, C. Y.; Andreyev, A.; Austin, R. A. E.; Ball, G. C.; Bandyopadhyay, D.; Becker, J. A.; Boston, A. J.; Boston, H. C.; Buchmann, L.; Churchman, R.; Cifarelli, F.; Cooper, R. J.; Cross, D. S.; Dashdorj, D.; Demand, G. A.; Dimmock, M. R.; Drake, T. E.; Finlay, P.; Gallant, A. T.; Garrett, P. E.; Green, K. L.; Grint, A. N.; Grinyer, G. F.; Harkness, L. J.; Hayes, A. B.; Kanungo, R.; Lisetskiy, A. F.; Leach, K. G.; Lee, G.; Maharaj, R.; Martin, J.-P.; Moisan, F.; Morton, A. C.; Mythili, S.; Nelson, L.; Newman, O.; Nolan, P. J.; Orce, J. N.; Padilla-Rodal, E.; Phillips, A. A.; Porter-Peden, M.; Ressler, J. J.; Roy, R.; Ruiz, C.; Sarazin, F.; Scraggs, D. P.; Waddington, J. C.; Wan, J. M.; Whitbeck, A.; Williams, S. J.; Wong, J.

    2009-12-01

    The low-energy structures of the radioactive nuclei 20, 21Na have been examined using Coulomb excitation at the TRIUMF-ISAC radioactive ion beam facility. Beams of ˜ 5×106 ions/s were accelerated to 1.7MeV/A and Coulomb excited in a 0.5mg/cm^2 natTi target. Two TIGRESS HPGe clover detectors perpendicular to the beam axis were used for γ -ray detection, while scattered nuclei were observed by the Si detector BAMBINO. For 21Na , Coulomb excitation from the 3/2+ ground state to the first excited 5/2+ state was observed, while for 20Na , Coulomb excitation was observed from the 2+ ground state to the first excited 3+ and 4+ states. For both beams, B ( λ L) values were determined using the 2+ rightarrow 0+ de-excitation in 48Ti as a reference. The resulting B( E2) ↓ value for 21Na is 137±9 e^2fm^4, while the resulting B( λ L) ↓ values for 20Na are 55±6 e^2fm^4 for the 3+ rightarrow 2+ , 35.7±5.7 e^2 fm^4 for the 4+ rightarrow 2+ , and 0.154±0.030 μ_ N^2 for the 4+ rightarrow 3+ transitions. This analysis significantly improves the measurement of the 21Na B( E2) value, and provides the first experimental determination of B( λ L) values for the proton dripline nucleus 20Na .-1

  1. The plant vacuolar Na+/H+ antiport.

    Science.gov (United States)

    Barkla, B J; Apse, M P; Manolson, M F; Blumwald, E

    1994-01-01

    Salt stress imposes severe limitations on plant growth, however, the extent of growth reduction depends upon the soil salinity level and the plant species. One of the mechanisms employed by salt tolerant plants is the effective vacuolar compartmentalization of sodium. The sequestration of sodium into the vacuole occurs by the operation of a Na+/H+ antiport located at the tonoplast. Evidence for a plant vacuolar Na+/H+ antiport has been demonstrated in tissues, intact vacuoles and isolated tonoplast vesicles. In sugar beet cell suspensions, the activity of the vacuolar Na+/H+ antiport increased with increasing NaCl concentrations in the growth medium. This increased activity was correlated with the increased synthesis of a 170 kDa tonoplast polypeptide. In vivo labelling of tonoplast proteins showed the enhanced synthesis of the 170 kDa polypeptide not only upon exposure of the cells to salt, but also when the cells were grown in the presence of amiloride. Exposure of the cells to amiloride also resulted in increased vacuolar Na+/H+ antiport activity. Polyclonal antibodies raised against the 170 kDa polypeptide almost completely inhibited the antiport activity, suggesting the association of this protein with the plant vacuolar Na+/H+ antiport. Antibodies against the Na+/H+ antiport-associated polypeptide were used to screen a Beta lambda ZAP expression library. A partial clone of 1.65 kb was sequenced and found to encode a polypeptide with a putative transmembrane domain and a large hydrophilic C terminus. This clone showed no homology to any previously cloned gene at either the nucleic acid or the amino acid level.

  2. TweetNaCl : a crypto library in 100 tweets

    NARCIS (Netherlands)

    Bernstein, D.J.; van Gastel, B.; Janssen, W.; Lange, T.; Schwabe, P.; Smetsers, S.; Aranha, D.F.; Menezes, A.

    2015-01-01

    This paper introduces TweetNaCl, a compact reimplementation of the NaCl library, including all 25 of the NaCl functions used by applications. TweetNaCl is published on Twitter and fits into just 100 tweets; the tweets are available from anywhere, any time, in an unsuspicious way. Distribution via

  3. Kupokelewa Zaidi Kwa Simu Ya Mkononi Kuliko Kompyuta Na ...

    African Journals Online (AJOL)

    Mtandao wa tovuti ni nyenzo ya msingi katika maendeleo ya uwanja wa mawasiliano unaounganisha watu na jamii mbalimbali katika ulimwengu wa leo unaotandawaa. Katika “ulimwengu wa kwanza na wa pili”, yaani mabara ya Amerika, Uropa na Asia, maendeleo na mapinduzi makubwa katika uwanja wa teknolojia ya ...

  4. Mabadiliko Ya Kifonolojia Na Kimofolojia Wakati Wa Utohozi Wa ...

    African Journals Online (AJOL)

    Mwingiliano wa lugha ya Kiswahili na Kiarabu una historia ndefu kidogo. Inasemekana Waarabu walianza muwasala na 'Waswahili' tangu karne ya kwanza (BK) (Polome 1967:9). Kutokana na muwasala huo wa muda mrefu, lugha hizi mbili (Kiarabu na Kiswahili) zimeathiriana sana. Lakini kuna maoni kwamba Kiarabu ...

  5. O Passeio Público do Rio de Janeiro na Literatura, na Pintura e na Fotografia do Século XIX

    Directory of Open Access Journals (Sweden)

    Solange de Aragão

    2012-06-01

    Full Text Available Este artigo tem como objetivo geral e mais amplo chamar a atenção dos pesquisadores para a importância da literatura, da pintura e da fotografia como fontes documentais para a construção da História do Paisagismo no Brasil por meio de um estudo de caso muito particular: o Passeio Público do Rio de Janeiro no século XIX. São objetivos específicos apresentar e analisar o modo como esse espaço livre público aparece na literatura, na pintura e na fotografia desse período, considerando suas transformações paisagísticas.

  6. VPLIV CENE NA ZADOVOLJSTVO IN ZVESTOBO UPORABNIKOV TELEKOMUNIKACIJSKIH STORITEV

    OpenAIRE

    Majcen, Mateja

    2016-01-01

    Cena izdelka ali storitve, ki jo plača uporabnik, ima pomemben vpliv na zadovoljstvo ali nezadovoljstvo uporabnika z uporabo tega izdelka ali storitve in posledično na zadovoljstvo do podjetja. Glede na to, da se različni avtorji strinjajo in to tudi dokazujejo z raziskavami, zadovoljstvo nedvoumno vpliva na zvestobo uporabnika, zvestoba pa na dolgoročno uspešnost podjetja, smo v delu ugotavljali, kako sama cena storitve vpliva na zadovoljstvo in kako posredno preko zadovoljstva vpliva na zve...

  7. Molecular dynamics investigation of Na+ in Na2Ni2TeO6

    International Nuclear Information System (INIS)

    Sau, Kartik; Kumar, P. Padma

    2014-01-01

    An inter-atomic potential for Na 2 Ni 2 TeO 6 in the Parrinello- Rahman-Vashishta (PRV) model is parameterized empirically. The potential reproduces variety of structural and transport properties of that material in good agreement with recent experimental results. The study provides fresh insights on the migration channels and mechanism of Na + in the system

  8. Muziki wa Hip Hop na Haki Za Kijamii: Dhima, Changamoto na ...

    African Journals Online (AJOL)

    Ni dhahiri kuwa haki za kijamii zinaweza kuwasilishwa kwa jamii pana kupitia sanaa ya hip hop. Makala haya basi, yanabainisha dhima na mchango wa muziki wa hip hop katika masuala ya haki za kijamii, yanafafanua changamoto za muziki huu katika kuwasilisha haki za kijamii na kutoa mapendekezo kwa makundi ...

  9. NaI(Tl) electron energy resolution

    CERN Document Server

    Mengesha, W

    2002-01-01

    NaI(Tl) electron energy resolution eta sub e was measured using the Modified Compton Coincidence Technique (MCCT). The MCCT allowed detection of nearly monoenergetic internal electrons resulting from the scattering of incident 662 keV gamma rays within a primary NaI(Tl) detector. Scattered gamma rays were detected using a secondary HPGe detector in a coincidence mode. Measurements were carried out for electron energies ranging from 16 to 438 keV, by varying the scattering angle. Measured HPGe coincidence spectra were deconvolved to determine the scattered energy spectra from the NaI(Tl) detector. Subsequently, the NaI(Tl) electron energy spectra were determined by subtracting the energy of scattered spectra from the incident source energy (662 keV). Using chi-squared minimization, iterative deconvolution of the internal electron energy spectra from the measured NaI(Tl) spectra was then used to determine eta sub e at the electron energy of interest. eta sub e values determined using this technique represent va...

  10. Anion-coupled Na efflux mediated by the human red blood cell Na/K pump

    International Nuclear Information System (INIS)

    Dissing, S.; Hoffman, J.F.

    1990-01-01

    The red cell Na/K pump is known to continue to extrude Na when both Na and K are removed from the external medium. Because this ouabain-sensitive flux occurs in the absence of an exchangeable cation, it is referred to as uncoupled Na efflux. This flux is also known to be inhibited by 5 mM Nao but to a lesser extent than that inhibitable by ouabain. Uncoupled Na efflux via the Na/K pump therefore can be divided into a Nao-sensitive and Nao-insensitive component. We used DIDS-treated, SO4-equilibrated human red blood cells suspended in HEPES-buffered (pHo 7.4) MgSO4 or (Tris)2SO4, in which we measured 22Na efflux, 35SO4 efflux, and changes in the membrane potential with the fluorescent dye, diS-C3 (5). A principal finding is that uncoupled Na efflux occurs electroneurally, in contrast to the pump's normal electrogenic operation when exchanging Nai for Ko. This electroneutral uncoupled efflux of Na was found to be balanced by an efflux of cellular anions. (We were unable to detect any ouabain-sensitive uptake of protons, measured in an unbuffered medium at pH 7.4 with a Radiometer pH-STAT.) The Nao-sensitive efflux of Nai was found to be 1.95 +/- 0.10 times the Nao-sensitive efflux of (SO4)i, indicating that the stoichiometry of this cotransport is two Na+ per SO4=, accounting for 60-80% of the electroneutral Na efflux. The remainder portion, that is, the ouabain-sensitive Nao-insensitive component, has been identified as PO4-coupled Na transport and is the subject of a separate paper. That uncoupled Na efflux occurs as a cotransport with anions is supported by the result, obtained with resealed ghosts, that when internal and external SO4 was substituted by the impermeant anion, tartrate i,o, the efflux of Na was inhibited 60-80%. This inhibition could be relieved by the inclusion, before DIDS treatment, of 5 mM Cli,o

  11. Na/K pump inactivation, subsarcolemmal Na measurements, and cytoplasmic ion turnover kinetics contradict restricted Na spaces in murine cardiac myocytes.

    Science.gov (United States)

    Lu, Fang-Min; Hilgemann, Donald W

    2017-07-03

    Decades ago, it was proposed that Na transport in cardiac myocytes is modulated by large changes in cytoplasmic Na concentration within restricted subsarcolemmal spaces. Here, we probe this hypothesis for Na/K pumps by generating constitutive transsarcolemmal Na flux with the Na channel opener veratridine in whole-cell patch-clamp recordings. Using 25 mM Na in the patch pipette, pump currents decay strongly during continuous activation by extracellular K (τ, ∼2 s). In contradiction to depletion hypotheses, the decay becomes stronger when pump currents are decreased by hyperpolarization. Na channel currents are nearly unchanged by pump activity in these conditions, and conversely, continuous Na currents up to 0.5 nA in magnitude have negligible effects on pump currents. These outcomes are even more pronounced using 50 mM Li as a cytoplasmic Na congener. Thus, the Na/K pump current decay reflects mostly an inactivation mechanism that immobilizes Na/K pump charge movements, not cytoplasmic Na depletion. When channel currents are increased beyond 1 nA, models with unrestricted subsarcolemmal diffusion accurately predict current decay (τ ∼15 s) and reversal potential shifts observed for Na, Li, and K currents through Na channels opened by veratridine, as well as for Na, K, Cs, Li, and Cl currents recorded in nystatin-permeabilized myocytes. Ion concentrations in the pipette tip (i.e., access conductance) track without appreciable delay the current changes caused by sarcolemmal ion flux. Importantly, cytoplasmic mixing volumes, calculated from current decay kinetics, increase and decrease as expected with osmolarity changes (τ >30 s). Na/K pump current run-down over 20 min reflects a failure of pumps to recover from inactivation. Simulations reveal that pump inactivation coupled with Na-activated recovery enhances the rapidity and effectivity of Na homeostasis in cardiac myocytes. In conclusion, an autoregulatory mechanism enhances cardiac Na/K pump activity when

  12. Muscle K+, Na+, and Cl- disturbances and Na+-K+ pump inactivation: implications for fatigue

    DEFF Research Database (Denmark)

    McKenna, Michael J; Bangsbo, Jens; Renaud, Jean-Marc

    2008-01-01

    (+)-ATPase activity during exercise stabilizes Na(+) and K(+) concentration gradients and membrane excitability and thus protects against fatigue. However, during intense contraction some Na(+)-K(+) pumps are inactivated and together with further ionic disturbances, likely precipitate muscle fatigue.......Membrane excitability is a critical regulatory step in skeletal muscle contraction and is modulated by local ionic concentrations, conductances, ion transporter activities, temperature, and humoral factors. Intense fatiguing contractions induce cellular K(+) efflux and Na(+) and Cl(-) influx......, causing pronounced perturbations in extracellular (interstitial) and intracellular K(+) and Na(+) concentrations. Muscle interstitial K(+) concentration may increase 1- to 2-fold to 11-13 mM and intracellular K(+) concentration fall by 1.3- to 1.7-fold; interstitial Na(+) concentration may decline by 10 m...

  13. Metallic Na formation in NaCl crystals with irradiation of electron or vacuum ultraviolet photon

    Energy Technology Data Exchange (ETDEWEB)

    Owaki, Shigehiro [Osaka Prefecture Univ., Sakai, Osaka (Japan). Coll. of Integrated Arts and Sciences; Koyama, Shigeko; Takahashi, Masao; Kamada, Masao; Suzuki, Ryouichi

    1997-03-01

    Metallic Na was formed in NaCl single crystals with irradiation of a variety of radiation sources and analyzed the physical states with several methods. In the case of irradiation of 21 MeV electron pulses to the crystal blocks, the optical absorption and lifetime measurement of positron annihilation indicated appearance of Na clusters inside. Radiation effects of electron beam of 30 keV to the crystals in vacuum showed the appearance of not only metallic Na but atomic one during irradiation with Auger electron spectroscopy. Intense photon fluxes in vacuum ultraviolet region of synchrotron radiation were used as another source and an analyzing method of ultraviolet photoelectron spectroscopy. The results showed the metallic Na layered so thick that bulk plasmon can exist. (author)

  14. Hydrolysis of Rice Straw Pretreated by Na2SO3 Over Fe-resin/NaCl

    Directory of Open Access Journals (Sweden)

    YANG Hui

    2017-05-01

    Full Text Available To increase the conversion of rice straw(RS and the yield of products, we employed three methods, which were ultrasonic wave, steam explosion and Na2SO3 pretreatment to pretreat RS(the treated RS noted as CS-RS, ZQ-RS and Na2SO3-RS, respectively and found that Na2SO3 treatment was the best pretreatment method based on XRD, SEM, elemental analysis and content of cellulose, hemicellulose and lignin. The conversion of Na2SO3-RS and the yield of total reducing sugar(TRS and levulinic acid(LA were 97.3%, 29.6% and 13.5%, respectively by 10% Fe-resin in 3.3% NaCl solution under 200 ℃.

  15. Na-ion dynamics in Quasi-1D compound NaV2O4

    International Nuclear Information System (INIS)

    Månsson, M; Umegaki, I; Nozaki, H; Higuchi, Y; Sugiyama, J; Kawasaki, I; Watanabe, I; Sakurai, H

    2014-01-01

    We have used the pulsed muon source at ISIS to study high-temperature Na-ion dynamics in the quasi-one-dimensional (Q1D) metallic antiferromagnet NaV 2 O 4 . By performing systematic zero-field and longitudinal-field measurements as a function of temperature we clearly distinguish that the hopping rate increases exponentially above T diff ≈ 250 K. The data is well fitted to an Arrhenius type equation typical for a diffusion process, showing that the Na-ions starts to be mobile above T diff . Such results make this compound very interesting for the tuning of Q1D magnetism using atomic-scale ion-texturing through the periodic potential from ordered Na-vacancies. Further, it also opens the door to possible use of NaV 2 O 4 and related compounds in energy related applications

  16. Summer sudden Na number density enhancements measured with the ALOMAR Weber Na Lidar

    Directory of Open Access Journals (Sweden)

    D. Heinrich

    2008-05-01

    Full Text Available We present summer Na-densities and atmospheric temperatures measured 80 to 110 km above the Arctic Lidar Observatory for Middle Atmosphere Research (ALOMAR. The Weber Na Lidar is part of ALOMAR, located at 69° N in Norway, 150 km north of the Arctic Circle. The sun does not set here during the summer months, and measurements require a narrowband Faraday Anomalous Dispersion Optical Filter (FADOF.

    We discuss an observed sudden enhancement in the Na number density around 22:00 UT on 1 to 2 June 2006. We compare this observation with previous summer measurements and find a frequent appearance of Na number density enhancements near local midnight. We describe the time of appearance, the altitude distribution, the duration and the strength of these enhancements and compare them to winter observations. We investigate possible formation mechanisms and, as others before, we find a strong link between these Na number density enhancements and sporadic E layers.

  17. Summer sudden Na number density enhancements measured with the ALOMAR Weber Na Lidar

    Directory of Open Access Journals (Sweden)

    D. Heinrich

    2008-05-01

    Full Text Available We present summer Na-densities and atmospheric temperatures measured 80 to 110 km above the Arctic Lidar Observatory for Middle Atmosphere Research (ALOMAR. The Weber Na Lidar is part of ALOMAR, located at 69° N in Norway, 150 km north of the Arctic Circle. The sun does not set here during the summer months, and measurements require a narrowband Faraday Anomalous Dispersion Optical Filter (FADOF. We discuss an observed sudden enhancement in the Na number density around 22:00 UT on 1 to 2 June 2006. We compare this observation with previous summer measurements and find a frequent appearance of Na number density enhancements near local midnight. We describe the time of appearance, the altitude distribution, the duration and the strength of these enhancements and compare them to winter observations. We investigate possible formation mechanisms and, as others before, we find a strong link between these Na number density enhancements and sporadic E layers.

  18. Structure-function relationships of Na+, K+, ATP, or Mg2+ binding and energy transduction in Na,K-ATPase

    DEFF Research Database (Denmark)

    Jorgensen, Peter L.; Pedersen, Per Amstrup

    2000-01-01

    Na,K-ATPase; Mutagenesis; Na+ binding; K+ binding; Tl+ binding; Mg2+ binding; ATP binding; Cation binding site; Energy transduction......Na,K-ATPase; Mutagenesis; Na+ binding; K+ binding; Tl+ binding; Mg2+ binding; ATP binding; Cation binding site; Energy transduction...

  19. Na2SO4-based solid electrolytes for SOx sensors

    DEFF Research Database (Denmark)

    Rao, N.; Schoonman, J.; Toft Sørensen, O.

    1992-01-01

    on the phases present and the structure of the specimens. From a point of view of practical application as SOx sensor material, the Na2SO4 + 5 mol% Y2(SO4)3 + Na2WO4 and Na2SO4+ 4 mol% La2(SO4)3 + Na2WO4 materials are better than undoped Na2SO4 because of their higher conductivity, and absence of a phase...

  20. Long-Range Effects of Na(+) Binding in Na,K-ATPase Reported by ATP.

    Science.gov (United States)

    Middleton, David A; Fedosova, Natalya U; Esmann, Mikael

    2015-12-01

    This paper addresses the question of long-range interactions between the intramembranous cation binding sites and the cytoplasmic nucleotide binding site of the ubiquitous ion-transporting Na,K-ATPase using (13)C cross-polarization magic-angle spinning (CP-MAS) solid-state nuclear magnetic resonance. High-affinity ATP binding is induced by the presence of Na(+) as well as of Na-like substances such as Tris(+), and these ions are equally efficient promoters of nucleotide binding. CP-MAS analysis of bound ATP with Na,K-ATPase purified from pig kidney membranes reveals subtle differences in the nucleotide interactions within the nucleotide site depending on whether Na(+) or Tris(+) is used to induce binding. Differences in chemical shifts for ATP atoms C1' and C5' observed in the presence of Na(+) or Tris(+) suggest alterations in the residues surrounding the bound nucleotide, hydrogen bonding, and/or conformation of the ribose ring. This is taken as evidence of a long-distance communication between the Na(+)-filled ion sites in the membrane interior and the nucleotide binding site in the cytoplasmic domain and reflects the first conformational change ultimately leading to phosphorylation of the enzyme. Stopped-flow fluorescence measurements with the nucleotide analogue eosin show that the dissociation rate constant for eosin is larger in Tris(+) than in Na(+), giving kinetic evidence of the difference in structural effects of Na(+) and Tris(+). According to the recent crystal structure of the E1·AlF4(-)·ADP·3Na(+) form, the coupling between the ion binding sites and the nucleotide side is mediated by, among others, the M5 helix.

  1. Tecnologia simplificada na enfermagem materno infantil

    Directory of Open Access Journals (Sweden)

    Selma Campestrini

    1991-09-01

    Full Text Available A autora apresenta três modelos de tecnologia simplificada da enfermagem materno infantil: o equipamento didático SEIO COBAIA para treinar exercícios e massagens da mama e mamilo; a peça indumentária SUPRETRAUMA - sutiã preventivo de traumatismo mamilar - usado por gestantes; e, a técnica para reverter mamilo umbilicado durante o puerperio imediato. Além de corroborar na promoção do aleitamento materno e na prevenção de desmame precoce, demonstra a possibilidade da enfermagem relacionar o saber teórico-científico com o saber tecnico-prático, na saúde da mulher e da criança, com tecnologia adequada às necessidades, à compreensão e ao bem estar da população.

  2. Eletrencefalograma na síndrome parkinsoniana

    Directory of Open Access Journals (Sweden)

    José Geraldo Camargo Lima

    1973-09-01

    Full Text Available Foram estudados os eletrencefalogramas de 50 pacientes parkinsonianos livres de qualquer antecedente convulsivo, sendo registrados traçados anormais em 40% dos casos. A incidência de traçados anormais foi maior na síndrome parkinsoniana bilateral do que na unilateral (52% e 25%, respectivamente. Entre as anormalidades assinaladas foram as paroxísticas as mais freqüentes (65% dos casos, caracterizando-se predominantemente por surtos de ondas teta. O registro de anormalidades paroxísticas do tipo irritativo encontrado em três casos é salientado. Alterações da atividade de base foram assinaladas em 35% dos pacientes. A idade dos pacientes não parece ter tido importante papel na gênese das anormalidades eletrencefalográficas.

  3. GLOBAL COMMODITY CHAINS NA PERSPECTIVA DE MARKETING

    Directory of Open Access Journals (Sweden)

    Flávio Régio Brambilla

    2014-01-01

    Full Text Available O presente estudo visa a estabelecer uma relação entre as estratégias de canais globais com aspectos do marketing, como a força da marca. Trata-se de conciliar atributos de Estratégia e Marketing. As mudanças econômicas globais levaram a transformações na competição das empresas, obrigando-as a ingressar numa discussão aprimorada acerca das estratégias e competências. Com base na ideia da detenção do conhecimento e das habilidades como verdadeiros diferenciais competitivos, muitos players passam a atuar na gestão do design e da marca como elementos centrais das políticas de negócios, onde a proposição de valor pode ser mais bem definida aos mercados consumidores.

  4. Recent results from NA61/SHINE

    CERN Document Server

    Puławski, Szymon

    2015-01-01

    The main physics goals of the NA61/SHINE programme on strong interactions are the study of the properties of the onset of deconfinement and the search for signatures of the critical point of strongly interacting matter. These goals are pursued by performing an energy (beam momentum 13A -158A GeV/c) and system size (p+p, p+Pb, Be+Be, Ar+Sc, Xe+La) scan. This publication reviews results and plans of NA61/SHINE. In particular, recent inclusive spectra and new results on fluctuations and correlations of identified hadrons in inelastic p+p and centrality selected Be+Be interactions at the SPS energies are presented. The energy dependence of quantities inspired by the Statistical Model of the Early Stage (kink, horn and step) show unexpected behavior in p+p collisions. The NA61/SHINE results are compared with the corresponding data of other experiments and model predictions.

  5. Recent results from NA61/SHINE

    CERN Document Server

    Kowalski, Seweryn

    2015-01-01

    The aim of the NA61/SHINE ion programme is to explore the QCD phase diagram within the range of thermodynamical variables accessible by the SPS. Moreover the experiment provides precision hadron production measurements to improve computation of neutrino fluxes in neutrino oscillation experiments and for improving air shower simulations of cosmic-ray experiments. The main physics goals of the NA61/SHINE ion programme are the study of the properties of the onset of deconfinement and the search for signatures of the critical point of strongly interacting matter. These goals are pursued by performing an energy (beam momentum 13A – 158 A GeV/c) and system size (p+p, p+Pb, Be+Be, Ar+Sc, Xe+La) scan. This paper reviews the status and results of the NA61/SHINE experiment.

  6. A Study of the Distribution of Sodium Cations in the Zeolites NaX, NaY and ZnNaY Using Carbon Monoxide Adsorption and 23Na NMR Techniques

    Science.gov (United States)

    Seidel, A.; Boddenberg, B.

    1995-03-01

    The zeolites NaX, NaY, Zn(55)NaY, and Zn(74)NaY were investigated by means of carbon monoxide adsorption and with static and magic angle spinning (MAS) 23Na NMR spectroscopy. The Na+ distribution between the sodalite (ß)- and supercages of the fully hydrated zeolites NaX and NaY were found to agree with XRD results. In the hydrated zinc-exchanged zeolites the Na+ ions almost exclusively populate the ß-cages. The adsorption isotherms of CO in the dehydrated zeolites were analyzed quantitatively to yield the concentrations of Na+ residing in the supercages. The measured static and MAS 23Na NMR spectra were analyzed by comparing their widths and shapes with simulated central transition patterns and yield, inter alia, the concentrations of Na+ associated with the spectrum components. Arguments are put forward that 23Na NMR of dehydrated zeolites is well suited to distinguish Na+ cations in highly symmetric environments and mobile Na+ species from others located on general positions, but further resolution is hardly feasible.

  7. Crystal structure of a Na+-bound Na+,K+-ATPase preceding the E1P state.

    Science.gov (United States)

    Kanai, Ryuta; Ogawa, Haruo; Vilsen, Bente; Cornelius, Flemming; Toyoshima, Chikashi

    2013-10-10

    Na(+),K(+)-ATPase pumps three Na(+) ions out of cells in exchange for two K(+) taken up from the extracellular medium per ATP molecule hydrolysed, thereby establishing Na(+) and K(+) gradients across the membrane in all animal cells. These ion gradients are used in many fundamental processes, notably excitation of nerve cells. Here we describe 2.8 Å-resolution crystal structures of this ATPase from pig kidney with bound Na(+), ADP and aluminium fluoride, a stable phosphate analogue, with and without oligomycin that promotes Na(+) occlusion. These crystal structures represent a transition state preceding the phosphorylated intermediate (E1P) in which three Na(+) ions are occluded. Details of the Na(+)-binding sites show how this ATPase functions as a Na(+)-specific pump, rejecting K(+) and Ca(2+), even though its affinity for Na(+) is low (millimolar dissociation constant). A mechanism for sequential, cooperative Na(+) binding can now be formulated in atomic detail.

  8. MANAGEMENT DOGODKOV NA PRIMERU NIKE KONVENCIJE

    OpenAIRE

    Kapić, Sara

    2010-01-01

    V diplomski nalogi je predstavljen potek ustvarjanja in izvedbe dogodka, ki zajema številne aktivnosti, in sicer na primeru Nike konvencije. Namen diplomske naloge je namreč podati kritično oceno izvajanja aktivnosti, z namenom ugotoviti, katere aktivnosti bi se v okviru upravljanja z dogodkom lahko izpeljale boljše in podati predloge za uspešnejšo zasnovo in organizacijo naslednje Nike konvencije. Na podlagi posnetka je ugotovljeno, da je pri organizaciji, vodenju, izvedbi in nadzoru prihaja...

  9. A Imagem como Ruína

    Directory of Open Access Journals (Sweden)

    Míriam Volpe

    2001-12-01

    Full Text Available O dialogismo ente o filme Citizen Kane, de Orson Welles, e o poema “Kubla Khan”, de S.T. Coleridgé, é analisado, sendo evidenciados não só o tema em comum – o mito do Paraíso perdido – como também a similariedade na organização do disurso na justaposição das images, como fragmentos da memória a serem preservados.

  10. Recent results and prospects from NA62

    Directory of Open Access Journals (Sweden)

    Bizzeti Andrea

    2016-01-01

    K+ → π+ vv̄ is a theoretically very clean decay where indirect effects of new physics may be detectable. The NA62 apparatus has been significantly upgraded between 2008 and 2014 in order to measure the branching ratio of this decay with 10% precision. The NA62 experiment took data with the new setup in pilot runs in 2014 and 2015, reaching the design beam intensity. Results of first data quality studies in view of the 2016-2017 physics runs are presented.

  11. Prenova razsvetljave na Fakulteti za elektrotehniko

    OpenAIRE

    ŠTAJDOHAR, JAN

    2015-01-01

    Pri energetskem pregledu stavbe Fakultete za elektrotehniko v Ljubljani je bilo ugotovljeno, da je razsvetljava prostorov na fakulteti v veliko primerih stara, neprimerna in energetsko potratna. V diplomski nalogi smo se posvetili energetski analizi prenove razsvetljave predavalnice P7 in kabineta AZ101. Pri načrtovanju in izbiri svetil smo upoštevali vse tehnične in energetske smernice za učinkovito razsvetljavo prostorov za izobraževanje. V uvodu smo opisali fizikalne osnove svetlobe, k...

  12. Osteossarcoma parosteal: aspectos na radiologia convencional

    OpenAIRE

    Nanci Neto,Francisco; Marchiori,Edson; Vianna,Alberto Domingues; Aymoré,Ierecê Lins; Almeida,Ana Luiza Brito de; Irion,Klaus L.; Collares,Felipe Birchal

    2007-01-01

    OBJETIVO: Avaliar os achados clínicos mais importantes do osteossarcoma parosteal e descrever os seus aspectos mais comuns na radiologia convencional. MATERIAIS E MÉTODOS: Estudo retrospectivo com 26 pacientes com osteossarcoma parosteal, provenientes do arquivo do Clube do Osso, Rio de Janeiro, RJ, e análise dos principais achados clínicos e aspectos radiológicos. RESULTADOS: A doença predominou em pacientes do sexo feminino e teve idade média de acometimento na terceira década de vida. Os a...

  13. Lamiaceae na Serra Negra, Minas Gerais, Brasil

    OpenAIRE

    Mota, Michelle Christine de Almeida; Pastore, José Floriano Barêa; Marques Neto, Roberto; Harley, Raymond Mervyn; Salimena, Fátima Regina

    2017-01-01

    Resumo A Serra Negra está inserida na área do Complexo da Serra da Mantiqueira, no domínio da Mata Atlântica, com altitudes entre 800 e 1.650 m, com vegetação em mosaico representada, entre outros, por campos rupestres em afloramentos quartzíticos e floresta nebulares. A família Lamiaceae (Labiatae) está representada na Serra Negra por 10 gêneros e 17 espécies: Aegiphila integrifolia, Cantinoa carpinifolia, C. macrotera, C. muricata, Eriope macrostachya, Hoehnea scutellarioides, Hyptidendron ...

  14. VARNOSTNA POLITIKA NA PODROČJU INFORMATIKE

    OpenAIRE

    Šavor, Gašper

    2011-01-01

    Informacijska tehnologija postaja vse bolj pomemben del poslovanja vsakega podjetja ter ţivljenja vsakega posameznika. Zato je v interesu vseh, da so ključne informacije dobro zaščitene. V prvem delu diplomske naloge smo predstavili informacijske sisteme, njihovo delitev ter vrste. Prav tako smo podrobneje predstavili ţivljenjski cikel ter 4-stopenjski model razvoja informacijskega sistema. V osrednjem delu naloge smo se osredotočili na nevarnosti na področju informatike ter vrste zašči...

  15. ARTE E TRANSGRESSÃO NA MODERNIDADE

    OpenAIRE

    Cascelli Farinasso, Gabriela

    2014-01-01

    O presente artigo busca explorar a arte como ferramenta para mudanças sociais na modernidade relacionando-a com os conceitos apresentados por Nicolas Bourriaud em seu livro Estética Relacional. A Street Art é apresentada como recorte dentre os movimentos artísticos, ressaltando-se sua importância e suas características do ponto de vista espacial e temporal e na criação de “lugares de pausa” no meio urbano, que levam o observador a refletir sobre a obra e o desviam do seu percurso. A transgres...

  16. O passado presente na literatura angolana

    Directory of Open Access Journals (Sweden)

    Rita Chaves

    2000-03-01

    Full Text Available A poderosa presença da História na configuração do projeto literário angolano assegura ao passado um lugar de destaque. Como matriz de significados no processo de construção da identidade cultural de uma sociedade em manifesto movimento, o passado ganha formas e sentidos múltiplos que interferem na leitura do presente e nas projeções do futuro realizadas pelos escritores angolanos, do período colonialaos nossos dias.

  17. Controlo de qualidade na empresa Valvie

    OpenAIRE

    Agrela, Sandra da Conceição Rodrigues

    2015-01-01

    Dissertação apresentada à Escola Superior Agrária do Instituto Politécnico de Castelo Branco para cumprimento dos requisitos necessários à obtenção do grau de Mestre em Inovação e Qualidade na Produção Alimentar. A qualidade está presente na realidade das indústrias atualmente mais do que nunca. Partindo do princípio de que qualidade seja atender e superar a expetativa do consumidor, a empresa que apresentar melhor performance nesse quesito será a de maior sucesso no mercado...

  18. O sentimento de respeito na moral kantiana

    OpenAIRE

    Stadnick, Maria Margareth

    2007-01-01

    Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Filosofia e Ciências Humanas. Programa de Pós-Graduação em Filosofia. A presente pesquisa tem como proposta fundamental a investigação do sentimento de respeito na moral kantiana. Neste sentido, nos detemos a investigar sua relação com a proposta moral de Kant, assim como verificarmos o lugar sistemático que ocupa o sentimento de respeito na moral kantiana. Dentro desse espírito, buscamos reconstruir a estrutura arg...

  19. Status for 2017, CERN NA63

    CERN Document Server

    Uggerhoej, UI

    2017-01-01

    In the NA63 experiment of May-June 2017 the purpose was to look for the effect of classical radiation reaction as described in \\cite{DiPiazza20171} but for 50 GeV positrons aligned to the (110) plane of silicon crystals of varying thicknesses in the range 1-6 mm. The data which was taken during the run shows promising results, but the final verdict awaits accurate calculations of the theoretically expected spectra, and a final analysis. For the 2016 results on quantum radiation reaction obtained by CERN NA63, we have submitted a manuscript, which is presently under refereeing \\cite{Wist17}.

  20. O problema do conhecimento verdadeiro na epidemiologia

    Directory of Open Access Journals (Sweden)

    Ayres José Ricardo de Carvalho Mesquita

    1992-01-01

    Full Text Available São examinadas as bases filosóficas da validação do conhecimento científico, com o intuito de estabelecer uma visão crítica a respeito da adoção das proposições de Popper na epidemiologia. Ressalta-se o caráter conservador que resulta das limitações técnicas implicadas na sua adoção, não obstante o evidente aumento da racionalidade e da criatividade heurística que propicia.

  1. Europlanet-2020 NA1 Exchange Program

    Science.gov (United States)

    Genzer, M.; Szego, K.; Haukka, H.; Harri, A.-M.

    2017-09-01

    The task of Exchange Program of NA1 is to support the activities of EPN2020 with experts and scientific exchange whenever it is needed. Short visits (up to 1 week) with the goal of improving infrastructure facilities and services offered to the scientific community are supported from this task. Since the start of the EPN2020 in September 2015 we have received and approved 14 applications for exchange program travel. More general and specifically targeted calls are planned for the future. The calls are announced on Europlanet-2020 NA1 web site.

  2. Na+/K+-ATPase: Activity and inhibition

    Science.gov (United States)

    Čolović, M.; Krstić, D.; Krinulović, K.; Momić, T.; Savić, J.; Vujačić, A.; Vasić, V.

    2009-09-01

    The aim of the study was to give an overview of the mechanism of inhibition of Na+/K+-ATPase activity induced by some specific and non specific inhibitors. For this purpose, the effects of some ouabain like compounds (digoxin, gitoxin), noble metals complexes ([PtCl2DMSO2], [AuCl4]-, [PdCl4]2-, [PdCl(dien)]+, [PdCl(Me4dien)]+), transition metal ions (Cu2+, Zn2+, Fe2+, Co2+), and heavy metal ions (Hg2+, Pb2+, Cd2+) on the activity of Na+/K+-ATPase from rat synaptic plasma membranes (SPM), porcine cerebral cortex and human erythrocytes were discussed.

  3. Na, K-ATPase as signaling transducer

    OpenAIRE

    Li, Juan

    2007-01-01

    It is now generally agreed that Na,K-ATPase (NKA), in addition to its role in the maintenance of Na+ and K+ gradients across the cell membrane, is a signal transducer. Our group has identified a novel signaling pathway where NKA interact with IP3R to form a signaling microdomain. Ouabain, a specific ligand of NKA, activates this pathway, triggers slow Ca2+ oscillations and activates NF-κB. In current study, the molecular mechanisms and some important downstream effects of NK...

  4. Glutathionylation-Dependence of Na(+)-K(+)-Pump Currents Can Mimic Reduced Subsarcolemmal Na(+) Diffusion.

    Science.gov (United States)

    Garcia, Alvaro; Liu, Chia-Chi; Cornelius, Flemming; Clarke, Ronald J; Rasmussen, Helge H

    2016-03-08

    The existence of a subsarcolemmal space with restricted diffusion for Na(+) in cardiac myocytes has been inferred from a transient peak electrogenic Na(+)-K(+) pump current beyond steady state on reexposure of myocytes to K(+) after a period of exposure to K(+)-free extracellular solution. The transient peak current is attributed to enhanced electrogenic pumping of Na(+) that accumulated in the diffusion-restricted space during pump inhibition in K(+)-free extracellular solution. However, there are no known physical barriers that account for such restricted Na(+) diffusion, and we examined if changes of activity of the Na(+)-K(+) pump itself cause the transient peak current. Reexposure to K(+) reproduced a transient current beyond steady state in voltage-clamped ventricular myocytes as reported by others. Persistence of it when the Na(+) concentration in patch pipette solutions perfusing the intracellular compartment was high and elimination of it with K(+)-free pipette solution could not be reconciled with restricted subsarcolemmal Na(+) diffusion. The pattern of the transient current early after pump activation was dependent on transmembrane Na(+)- and K(+) concentration gradients suggesting the currents were related to the conformational poise imposed on the pump. We examined if the currents might be accounted for by changes in glutathionylation of the β1 Na(+)-K(+) pump subunit, a reversible oxidative modification that inhibits the pump. Susceptibility of the β1 subunit to glutathionylation depends on the conformational poise of the Na(+)-K(+) pump, and glutathionylation with the pump stabilized in conformations equivalent to those expected to be imposed on voltage-clamped myocytes supported this hypothesis. So did elimination of the transient K(+)-induced peak Na(+)-K(+) pump current when we included glutaredoxin 1 in patch pipette solutions to reverse glutathionylation. We conclude that transient K(+)-induced peak Na(+)-K(+) pump current reflects the effect

  5. Response of saliva Na/K ratio to changing Na supply of lactating cows under tropical conditions.

    Science.gov (United States)

    Thiangtum, Wandee; Schonewille, J Thomas; Verstegen, Martin Wa; Arsawakulsudhi, Supot; Rukkwamsuk, Theera; Hendriks, Wouter H

    2017-06-01

    Factorial determination of the sodium (Na) requirement of heat-stressed lactating cows is hindered by accurate estimates of the Na losses through sweat. Direct studies, therefore, may be needed requiring information on the time course of healthy animals to become Na depleted and the subsequent rate of repletion. The rate of Na depletion and subsequent rate of Na repletion with two levels of dietary Na to lactating dairy cows housed under tropical conditions were investigated using the salivary Na/K. The 12 lactating cows (salivary Na/K ratio 14.6) rapidly developed clinical signs of Na deficiency, including pica, polyuria and polydipsia, reduced body weight and reduced milk yield when fed a low-Na ration (0.33 g kg -1 dry matter (DM)) for 3 weeks. Deficiency symptoms were associated with a rapid decrease in salivary Na/K ratio to cows with NaCl to a ration concentration of 1.1 or 1.6 g Na kg -1 DM for 5 weeks did not restore salivary Na/K ratio to values of >6. A daily Na intake of heat-stressed lactating cows to a ration intake of 1.6 g Na kg -1 DM was insufficient to restore Na deficiency. One week was sufficient to deplete heat-stressed lactating cows of Na, allowing for rapid dose-response studies utilizing the salivary Na/K ratio as a parameter for Na status of cows under tropical conditions. © 2016 Society of Chemical Industry. © 2016 Society of Chemical Industry.

  6. Water transport by the renal Na(+)-dicarboxylate cotransporter

    DEFF Research Database (Denmark)

    Meinild, A K; Loo, D D; Pajor, A M

    2000-01-01

    . This solute-coupled influx of water took place in the absence of, and even against, osmotic gradients. There was a strict stoichiometric relationship between Na(+), substrate, and water transport of 3 Na(+), 1 dicarboxylate, and 176 water molecules/transport cycle. These results indicate that the renal Na......This study investigated the ability of the renal Na(+)-dicarboxylate cotransporter, NaDC-1, to transport water. Rabbit NaDC-1 was expressed in Xenopus laevis oocytes, cotransporter activity was measured as the inward current generated by substrate (citrate or succinate), and water transport...... was monitored by the changes in oocyte volume. In the absence of substrates, oocytes expressing NaDC-1 showed an increase in osmotic water permeability, which was directly correlated with the expression level of NaDC-1. When NaDC-1 was transporting substrates, there was a concomitant increase in oocyte volume...

  7. Presoja notranjih kontrol pri obračunu davka na dodano vrednost na primeru "Podjetja x"

    OpenAIRE

    Majcen, Borut

    2016-01-01

    Poslovanje podjetja si je ob odsotnosti notranjih kontrol nemogoče predstavljati. Podjetja so podvržena raznim tveganjem, še posebej v današnjih razmerah globalnega poslovanja, ko se podjetja soočajo z vedno novimi izzivi, kar prinaša tudi nova tveganja. Najučinkovitejši ukrep za obvladovanje tveganj predstavlja vzpostavitev sistema notranjih kontrol. Obvladovanje tveganj pa ne poteka samo na ravni podjetja kot celote, ampak je prisotno na vseh področjih delovanja podjetja, torej tudi na p...

  8. Intracellular Na(+) and metabolic modulation of Na/K pump and excitability in the rat suprachiasmatic nucleus neurons.

    Science.gov (United States)

    Wang, Yi-Chi; Yang, Jyh-Jeen; Huang, Rong-Chi

    2012-10-01

    Na/K pump activity and metabolic rate are both higher during the day in the suprachiasmatic nucleus (SCN) that houses the circadian clock. Here we investigated the role of intracellular Na(+) and energy metabolism in regulating Na/K pump activity and neuronal excitability. Removal of extracellular K(+) to block the Na/K pump excited SCN neurons to fire at higher rates and return to normal K(+) to reactivate the pump produced rebound hyperpolarization to inhibit firing. In the presence of tetrodotoxin to block the action potentials, both zero K(+)-induced depolarization and rebound hyperpolarization were blocked by the cardiac glycoside strophanthidin. Ratiometric Na(+) imaging with a Na(+)-sensitive fluorescent dye indicated saturating accumulation of intracellular Na(+) in response to pump blockade with zero K(+). The Na(+) ionophore monensin also induced Na(+) loading and hyperpolarized the membrane potential, with the hyperpolarizing effect of monensin abolished in zero Na(+) or by pump blockade. Conversely, Na(+) depletion with Na(+)-free pipette solution depolarized membrane potential but retained residual Na/K pump activity. Cyanide inhibition of oxidative phosphorylation blocked the Na/K pump to depolarize resting potential and increase spontaneous firing in most cells, and to raise intracellular Na(+) levels in all cells. Nonetheless, the Na/K pump was incompletely blocked by cyanide but completely blocked by iodoacetate to inhibit glycolysis, indicating the involvement of both oxidative phosphorylation and glycolysis in fueling the Na/K pump. Together, the results indicate the importance of intracellular Na(+) and energy metabolism in regulating Na/K pump activity as well as neuronal excitability in the SCN neurons.

  9. NA49: lead-lead collision

    CERN Multimedia

    1996-01-01

    This is an image of an actual lead ion collision taken from tracking detectors on the NA49 experiment, part of the heavy ion project at CERN. These collisions produce a very complicated array of hadrons as the heavy ions break up. It is hoped that one of these collisions will eventually create a new state of matter known as quark-gluon plasma.

  10. Leitura na escola: um barco à deriva?

    Directory of Open Access Journals (Sweden)

    Teixeira, Marlene

    2008-01-01

    Full Text Available Este artigo busca, na teoria da enunciação de É. Benveniste, elementos para repensar o trabalho com a leitura na escola. Considera que, na discussão das noções gêmeas de forma e sentido, o autor formula uma concepção de significado que, de um lado, pode deter a interpretação à deriva, implicada na visão de leitura centrada no leitor, e, de outro lado, possibilita que se transcenda a idéia de que é pela decifração mdo código que se dá o processo de construção do significado. Conclui que, no processo de leitura, é sempre de um trabalho com a língua que se trata, trabalho que se renova a cada ato de aproximação do aluno com o texto, porque a língua é submetida ao ato de enunciação

  11. NA48: Wiring up for Change

    CERN Multimedia

    2001-01-01

    The NA48 Collaboration is rebuilding its drift chambers ready for the experiment to start up again this coming July. An intricate task involving the soldering of over 24,000 wires! The future of the NA48 experiment is coming right down to the wire, that is, the wires which the Collaboration is installing in the clean room of Hall 887 on the Prévessin site. Six days a week, technicians are working in shifts to rebuild the experiment's drift chambers. The original chambers were damaged when a section of a vacuum tube imploded at the end of 1999. A year ago, CERN gave the green light for this essential part of the spectrometer to be rebuilt, so the NA48 experiment, which studies CP violation (see box), still has a bright future ahead of it. Three years of data-taking ahead The NA48 experiment aims to penetrate the secrets of CP (Charge Parity) violation. Charge and parity are two parameters which distinguish a particle from an antiparticle. In other words, an electron possesses a negative electric ...

  12. Haalbaarheid voortijdige liberalisering na 1 april 2009

    NARCIS (Netherlands)

    Baarsma, B.

    2009-01-01

    Al geruime tijd worden door de politiek, postbedrijven en vakbonden gesprekken gevoerd over de liberalisering van de postmarkt. In april 2008 is door de sociale partners een beginselakkoord gesloten en november 2008 is een CAO opgesteld. Het is de bedoeling om binnen 3½ jaar na liberalisering ten

  13. Experiment NA57 at the CERN SPS

    Czech Academy of Sciences Publication Activity Database

    Antinori, F.; Balada, A.; Barbera, R.; Píška, Karel; Staroba, Pavel; Závada, Petr

    1999-01-01

    Roč. 25, - (1999), s. 473-479 ISSN 0954-3899 Institutional research plan: CEZ:AV0Z1010920 Keywords : NA57 * production of strange, multistrange particles * baryons, antibaryons * ultrarelativistic nucleus - nucleus collisions * SPS * strangeness enhancement * number of participants Subject RIV: BF - Elementary Particles and High Energy Physics Impact factor: 1.620, year: 1999

  14. Pijn tijdens of na de wortelkanaalbehandeling

    NARCIS (Netherlands)

    Wesselink, P.R.

    2012-01-01

    Een wortelkanaalbehandeling kan pijn veroorzaken tijdens en/of na de behandeling. Tijdens de behandeling moet dan onderscheid worden gemaakt tussen pijn bij een pulpitis en pijn bij een necrotische pulpa. In beide gevallen kan die pijn effectief worden bestreden, afhankelijk van de toestand waarin

  15. Probing luminescence centers in Na rich feldspar

    DEFF Research Database (Denmark)

    Prasad, Amit Kumar; Lapp, Torben; Kook, Myung Ho

    2016-01-01

    our understanding of the luminescence mechanisms and recombination sites, in a sample of Na rich plagioclase feldspar (oligoclase). Both the UV and violet–blue emissions show resonant excitations arising from a distribution of energy levels. We propose, contrary to the general understanding...

  16. Acetylene diffusion in Na-Y zeolite

    Indian Academy of Sciences (India)

    ideal guest molecule to start with. Here we ... In that case the incoherent scattering law, Sinc(Q, ω), alone describes the dynamics. Q(=k−k0) is the .... The results of QENS measurements to study the diffusion of acetylene gas in zeolite. Na-Y at ...

  17. Therapy of hyperthyroidism with Na131I

    International Nuclear Information System (INIS)

    Kakehi, Hirotake; Furukawa, Takashi; Fukakusa, Shunichi; Futonaka, Hiroshi; Takahashi, Yuji

    1984-01-01

    Forty one patients of hyperthyroidism were treated with Na 131 I. Men and women are in the ratio 1:3.1. The ages of patients are between twenties and sixties and the forties are the highest in number. The observation period of clinical courses is between 1 and 8 years. The number of patients observed over 5 years are 51% of them and over 2 years are 83%. The treatment frequency is as follows: On 37 cases each one was treated once with Na 131 I. 2 cases twice, 1 case at 4 times in 3 years and 1 case at 5 times in 6 years. The treatment doses are between 4,000-6,000 rad (40-60 Gray). In the cases treated with the irradiation dose of 6,000 rad, we often saw hypothyroidism. In cases aiming 4,000-5,000 rad, there is a tendency of leaving hyperthyroidism unrecovered. In conclusion, the patients should be treated giving 4,000-5,000 rad or with Na 131 I doses of 3-6mCi. If the effects of the treatment are insufficient, the patients should be further treated with anti-thyroid drug or treated again with Na 131 I. As the result, there are at present 25 cases (61.0%) in normal status of the thyroid gland, 12 cases (29.2%) in hyperthyroidism and 4 cases (9.8%) in hypothyroidism totaling 41 cases in all. (author)

  18. Nucleotide binding to Na+/K+-ATPase

    Czech Academy of Sciences Publication Activity Database

    Kubala, Martin; Lánský, Zdeněk; Ettrich, R.; Plášek, J.; Teisinger, Jan; Amler, Evžen

    2005-01-01

    Roč. 272, č. S1 (2005), s. 191-191 E-ISSN 1742-4658. [FEBS Congress /30./ and IUBMB Conference /9./. 02.07.2005-07.07.2005, Budapest] Keywords : Na+/K+- ATPase * ATP binding * TNP-ATP Subject RIV: BO - Biophysics

  19. Concentratie gewasbeschermingsmiddelen na verhitting dompelbad bloembollen

    NARCIS (Netherlands)

    Bulle, A.A.E.; Lans, van der A.M.; Aanholt, van J.T.M.

    2014-01-01

    De meest gebruikte methode van ontsmetting van bloembollen en –knollen is een dompeling in een mix van fungiciden. In het proces van bolontsmetting worden partijen bollen na elkaar ontsmet in hetzelfde dompelbad. Met een partij bollen kan een dompelbad behoorlijk vervuild raken met bijvoorbeeld

  20. Laser trapping of 21Na atoms

    International Nuclear Information System (INIS)

    Lu, Zheng-Tian.

    1994-09-01

    This thesis describes an experiment in which about four thousand radioactive 21 Na (t l/2 = 22 sec) atoms were trapped in a magneto-optical trap with laser beams. Trapped 21 Na atoms can be used as a beta source in a precision measurement of the beta-asymmetry parameter of the decay of 21 Na → 21 Ne + Β + + v e , which is a promising way to search for an anomalous right-handed current coupling in charged weak interactions. Although the number o trapped atoms that we have achieved is still about two orders of magnitude lower than what is needed to conduct a measurement of the beta-asymmetry parameter at 1% of precision level, the result of this experiment proved the feasibility of trapping short-lived radioactive atoms. In this experiment, 21 Na atoms were produced by bombarding 24 Mg with protons of 25 MeV at the 88 in. Cyclotron of Lawrence Berkeley Laboratory. A few recently developed techniques of laser manipulation of neutral atoms were applied in this experiment. The 21 Na atoms emerging from a heated oven were first transversely cooled. As a result, the on-axis atomic beam intensity was increased by a factor of 16. The atoms in the beam were then slowed down from thermal speed by applying Zeeman-tuned slowing technique, and subsequently loaded into a magneto-optical trap at the end of the slowing path. The last two chapters of this thesis present two studies on the magneto-optical trap of sodium atoms. In particular, the mechanisms of magneto-optical traps at various laser frequencies and the collisional loss mechanisms of these traps were examined

  1. Učinak video igre "Flappy Bird" na adolescente

    OpenAIRE

    Horvat, Marija

    2018-01-01

    Ovaj diplomski rad nastoji predstaviti uvid u učinke videoigre Flappy Bird na adolescente, fokusirajući se pritom na to potiče li ona nasilno ponašanje te nastoji odgovoriti na pitanje koliko je ta videoigra bila popularna među adolescentima u Hrvatskoj te po čemu je smatraju posebnom, tj. specifičnom. U tu svrhu provedeno je anketno istraživanje, a isti anketni upitnik proveden je na terenu i putem interneta te su uspoređeni rezultati. Anketni upitnik konstruiran je na način da se prvi dio u...

  2. Fissuras lábio palatinas não sindrômicas: relação entre o sexo e a extensão clínica Non sindromic cleft lip and palate: relationship between sex and clinical extension

    Directory of Open Access Journals (Sweden)

    Daniella Reis Barbosa Martelli

    2012-10-01

    Full Text Available A fenda labial e/ou palatina representa a anomalia congênita mais comum na face. OBJETIVO: Descrever a correlação existente entre a fenda labial e/ou palatina não sindrômica e gênero e sua gravidade na população brasileira. MÉTODO: Estudo transversal, conduzido entre 2009 e 2011, em uma amostra de 366 pacientes. Os dados foram analisados com estatística descritiva e regressão logística multinomial com intervalo de 95% para estimar a probabilidade dos tipos de fenda labial e/ou palatina afetar os gêneros. RESULTADOS: Entre os 366 casos de fenda labial e/ou palatina não sindrômica, as fendas mais frequentes foram a fenda lábio-palatina, seguida, respectivamente, pela fenda labial e fenda palatina. As fendas palatinas foram mais frequentes entre as mulheres e a fenda lábio-palatina e fenda labial apenas predominaram nos homens. O risco de fenda labial em relação à fenda palatina foi de 2,19 vezes maior em homens quando comparados às mulheres; enquanto o risco de fenda labial e palatina em relação à fenda palatina apenas foi 2,78 vezes em homens, quando comparados às mulheres. CONCLUSÃO: Este estudo mostrou que há diferenças na distribuição de fendas labiais e/ou palatinas não sindrômicas entre homens e mulheres.Cleft lip and/or palate represent the most common congenital anomaly of the face. AIM: To describe the correlation between non-syndromic cleft lip and/or palate and gender, and its severity in the Brazilian population. METHODS: Cross-sectional study, between 2009 and 2011, in a sample of 366 patients. The data was analyzed with descriptive statistics and multinomial logistic regression with a 95% interval to estimate the likelihood of the types of cleft lip and/or palate affecting the genders. RESULTS: Among the 366 cases of non-syndromic cleft lip and/or palate, the more frequent clefts were cleft lip and palate, followed respectively by cleft lip and cleft palate. The cleft palates were more frequent in

  3. On the Stability of NaO2 in Na-O2 Batteries.

    Science.gov (United States)

    Liu, Chenjuan; Carboni, Marco; Brant, William R; Pan, Ruijun; Hedman, Jonas; Zhu, Jiefang; Gustafsson, Torbjörn; Younesi, Reza

    2018-04-25

    Na-O 2 batteries are regarded as promising candidates for energy storage. They have higher energy efficiency, rate capability, and chemical reversibility than Li-O 2 batteries; in addition, sodium is cheaper and more abundant compared to lithium. However, inconsistent observations and instability of discharge products have inhibited the understanding of the working mechanism of this technology. In this work, we have investigated a number of factors that influence the stability of the discharge products. By means of in operando powder X-ray diffraction study, the influence of oxygen, sodium anode, salt, solvent, and carbon cathode were investigated. The Na metal anode and an ether-based solvent are the main factors that lead to the instability and decomposition of NaO 2 in the cell environment. This fundamental insight brings new information on the working mechanism of Na-O 2 batteries.

  4. Regeneration of plantlets under NaCl stress from NaN3 treated ...

    African Journals Online (AJOL)

    use

    2011-11-16

    Nov 16, 2011 ... plant regeneration under NaCl stressed conditions was assessed in some sugarcane ( ... cell is a useful work for the establishment of pure form of ... balance. The relative water contents (RWC) were calculated .... J. Life Sci.

  5. Equilibrium chemical transformations in NaPO3 + NaCl melts

    International Nuclear Information System (INIS)

    Kovarskaya, E.N.; Rodionov, Yu.I.

    1988-01-01

    Because of the problems of the burial of solidified radioactive wastes into different geological rock formations, in particular into massives of rock-salt, the state of molten polyphosphate-chloride mixtures (taking into account the chemical character of the interaction of their components) for a prolonged period of time. The equilibrium products of the reaction in the NaPO 3 -NaCl system were studied in melts in air in the composition range of 30-70 mole % NaCl. It was shown that with increase in the NaCl content in the mixtures, the polyphosphate gradually depolymerizes to sodium tri-, di-, and monophosphates, and the composition of the equilibrium melts is dependent only on the ratio between the components in the initial molten mixtures. The time until the equilibrium is attained is shorter, the higher is the experimental temperature

  6. Transmural gradients in Na/K pump activity and [Na+]I in canine ventricle.

    Science.gov (United States)

    Gao, J; Wang, W; Cohen, I S; Mathias, R T

    2005-09-01

    There are well-documented differences in ion channel activity and action potential shape between epicardial (EPI), midmyocardial (MID), and endocardial (ENDO) ventricular myocytes. The purpose of this study was to determine if differences exist in Na/K pump activity. The whole cell patch-clamp was used to measure Na/K pump current (I(P)) and inward background Na(+)-current (I(inb)) in cells isolated from canine left ventricle. All currents were normalized to membrane capacitance. I(P) was measured as the current blocked by a saturating concentration of dihydro-ouabain. [Na(+)](i) was measured using SBFI-AM. I(P)(ENDO) (0.34 +/- 0.04 pA/pF, n = 17) was smaller than I(P)(EPI) (0.68 +/- 0.09 pA/pF, n = 38); the ratio was 0.50 with I(P)(MID) being intermediate (0.53 +/- 0.13 pA/pF, n = 19). The dependence of I(P) on [Na(+)](i) or voltage was essentially identical in EPI and ENDO (half-maximal activation at 9-10 mM [Na(+)](i) or approximately -90 mV). Increasing [K(+)](o) from 5.4 to 15 mM caused both I(P)(ENDO) and I(P)(EPI) to increase, but the ratio remained approximately 0.5. I(inb) in EPI and ENDO were nearly identical ( approximately 0.6 pA/pF). Physiological [Na(+)](i) was lower in EPI (7 +/- 2 mM, n = 31) than ENDO (12 +/- 3 mM, n = 29), with MID being intermediate (9 +/- 3 mM, n = 22). When cells were paced at 2 Hz, [Na(+)](i) increased but the differences persisted (ENDO 14 +/- 3 mM, n = 10; EPI 9 +/- 2 mM, n = 10; and MID intermediate, 11 +/- 2 mM, n = 9). Based on these results, the larger I(P) in EPI appears to reflect a higher maximum turnover rate, which implies either a larger number of active pumps or a higher turnover rate per pump protein. The transmural gradient in [Na(+)](i) means physiological I(P) is approximately uniform across the ventricular wall, whereas transporters that utilize the transmembrane electrochemical gradient for Na(+), such as Na/Ca exchange, have a larger driving force in EPI than ENDO.

  7. Isotope separation of 22Na and 24Na with using light induced drift effect

    International Nuclear Information System (INIS)

    Hradecny, C.; Tethal, T.; Ermolaev, I.M.; Zemlyanoj, S.G.; Zuzaan, P.

    1993-01-01

    The LIDIS (Light Drift Isotope Separation) separator without a gas flow is discussed. It is shown, that atomization degree of the separated isotopes limited real separation coefficient. The better buffer gas purification allowed to increase the experimental separation factor of 22 Na and 24 Na isotopes up to 25. The new experimental set up allow to increase the separation efficiency up to 50%. 12 refs.; 5 figs

  8. Análise dos efeitos de um programa de exercícios associado à massagem como medida preventiva para a Sindrome do Piriforme em corredores de longa distância - doi: 10.5102/ucs.v12i2.2701

    Directory of Open Access Journals (Sweden)

    Andreza Luiza de Almeida

    2014-12-01

    Full Text Available A Síndrome do piriforme é caracterizada pela compressão do nervo ciático, por se tratar de uma patologia muito frequente em atletas. O objetivo do estudo foi analisar o efeito do programa de exercícios associado à massagem em corredores fundistas. Este estudo caracterizou-se experimental. A amostra foi composta de 9 corredores que foram divididos aleatoriamente em 2 grupos A e B, com técnicas de massagens e alongamentos diferentes, realizado uma vez por semana. Foi realizada uma mensuração pré e pós-intervenção da rotação externa e interna do quadril e flexibilidade da coluna, para averiguar se ocorreu ganho na amplitude de movimento (ADM. Os resultados demonstraram que o "grupo A" obteve valores significativos (p<0,05 para o ganho de ADM em relação à média entre o "grupo B". Pode-se concluir o que os exercícios associados à massagem restabelecem a ADM e reduzem o risco de um possível acometimento a síndrome do piriforme em corredores.

  9. Intracellular Na+ regulation of Na+ pump sites in cultured vascular smooth muscle cells

    International Nuclear Information System (INIS)

    Allen, J.C.; Navran, S.S.; Seidel, C.L.; Dennison, D.K.; Amann, J.M.; Jemelka, S.K.

    1989-01-01

    Enzymatically dispersed cells from canine saphenous vein and femoral artery were grown in fetal calf serum and studied at day 0 (freshly dispersed) through confluence in primary culture. Intracellular Na levels (Nai), but not intracellular K (Ki), were increased after 24 h in culture and then decreased to a steady state by 4 days. Na+ pump site number [( 3 H] ouabain binding) increased through day 3 and remained elevated. Nai was still elevated at 2 days when the Na+ pump site number began to increase. Total pump turnover (maximum ouabain-inhibited 86 Rb uptake) reflected the increase in Na+ pump site number. These key events precede the observed increases in both protein production and cellular proliferation. If the same cells are maintained in defined medium, without fetal calf serum, Nai, Ki, and the number of [ 3 H]ouabain binding sites do not change with time. These data are consistent with the suggestion that the initial mitogenic response of vascular smooth muscle cells to fetal calf serum involves an increased Na+ influx, and a Nai accumulation, caused by low Na+ pump density. The synthesis of new pump sites effects a decrease in the accumulated Nai, which may be related to cell proliferation

  10. Vliv mikroflóry na senzorické vlastnosti vína

    OpenAIRE

    Petrášová, Ludmila

    2014-01-01

    Tato bakalářská práce se zabývá vlivem mikroflóry na senzorické vlastnosti vína. Teoretická část informuje o botanickém popisu hroznů vína Veltlínské zelené, dále o jeho složení, o technologii zpracování bílého vína a o vlivu kvasinek na aromatický profil vína. V další části popisuje metodu stanovení aromaticky aktivních látek pomocí plynové chromatografie v kombinaci s mikroextrakcí tuhou fází (SPME-GC). Cílem experimentální části bylo proměřit vzorky 4 různých moštů odrůdy Veltlínské zelené...

  11. Active transport of Na/sup +/ by reconstituted Na,K-ATPase

    Energy Technology Data Exchange (ETDEWEB)

    Boldyrev, A.A.; Svinukhova, I.A.

    1987-02-20

    The ability of ATP, CTP, ITP, GTP, and UTP to support ouabain-sensitive accumulation of Na/sup +/ by proteoliposomes with a reconstituted Na/K-pump was investigated. At a low (Na/sup +/)/(K/sup +/) ratio in the medium (20 mM/50 mM), a correlation is observed between the proton-accepting capacity of the nucleotide and its effectiveness as a substrate of active transport. To test the hypothesis of the importance of the presence of a negative charge in the 1-position of the purine (3-pyrimidine) base of the nucleotide for mutual transitions between the Na- and K-conformations of Na,K-ATPase they used two analogs of ATP: N/sub 1/-hydroxy-ATP, possessing proton acceptor capacity, and N/sub 1/-methoxy-ATP, in the molecule of which the negative charge is quenched by a methyl group. The first substrate supports active accumulation of Na/sup +/ in proteoliposomes at the same rate as ATP, whereas the second substrate is relatively ineffective.

  12. Transport of Na48 Drift Chambers to Dubna

    CERN Multimedia

    GOLOVATYUK, V

    2010-01-01

    On 22 July, in the occasion of the departure of the Na48 Drift Chambers from CERN, Mikhail Itkis (acting Director of the JIINR) and Rolf Heuer (CERN Director General) visited the NA62 experimental area.

  13. Regulation of Epithelial Sodium Transport via Epithelial Na+ Channel

    Science.gov (United States)

    Marunaka, Yoshinori; Niisato, Naomi; Taruno, Akiyuki; Ohta, Mariko; Miyazaki, Hiroaki; Hosogi, Shigekuni; Nakajima, Ken-ichi; Kusuzaki, Katsuyuki; Ashihara, Eishi; Nishio, Kyosuke; Iwasaki, Yoshinobu; Nakahari, Takashi; Kubota, Takahiro

    2011-01-01

    Renal epithelial Na+ transport plays an important role in homeostasis of our body fluid content and blood pressure. Further, the Na+ transport in alveolar epithelial cells essentially controls the amount of alveolar fluid that should be kept at an appropriate level for normal gas exchange. The epithelial Na+ transport is generally mediated through two steps: (1) the entry step of Na+ via epithelial Na+ channel (ENaC) at the apical membrane and (2) the extrusion step of Na+ via the Na+, K+-ATPase at the basolateral membrane. In general, the Na+ entry via ENaC is the rate-limiting step. Therefore, the regulation of ENaC plays an essential role in control of blood pressure and normal gas exchange. In this paper, we discuss two major factors in ENaC regulation: (1) activity of individual ENaC and (2) number of ENaC located at the apical membrane. PMID:22028593

  14. An enhancement to the NA4 gear vibration diagnostic parameter

    Science.gov (United States)

    Decker, Harry J.; Handschuh, Robert F.; Zakrajsek, James J.

    1994-01-01

    A new vibration diagnostic parameter for health monitoring of gears, NA4*, is proposed and tested. A recently developed gear vibration diagnostic parameter NA4 outperformed other fault detection methods at indicating the start and initial progression of damage. However, in some cases, as the damage progressed, the sensitivity of the NA4 and FM4 parameters tended to decrease and no longer indicated damage. A new parameter, NA4* was developed by enhancing NA4 to improve the trending of the parameter. This allows for the indication of damage both at initiation and also as the damage progresses. The NA4* parameter was verified and compared to the NA4 and FM4 parameters using experimental data from single mesh spur and spiral bevel gear fatigue rigs. The primary failure mode for the test cases was naturally occurring tooth surface pitting. The NA4* parameter is shown to be a more robust indicator of damage.

  15. Agmag Igbo dka Ngwar n'kwalite Ezi Nchekwa na Nkwsiike haobodo

    African Journals Online (AJOL)

    Ka Najira nwerechara onwe ya n'af 1960, olileanya tt mamala ya b na ihe ga-adz mma. Mana ka oge na-aga, a chptara na ihe na-akawanye nj. Usoro chch d iche iche daptara. Nd am na nd nkt achala mana nd gara n'ihu na-akawanye nj. O bu ihe doro anya na chch ha b nke nchgbu na fnfju akpa. N'agbanyegh na ...

  16. Angiotensin II-induced hypertension increases plasma membrane Na pump activity by enhancing Na entry in rat thick ascending limbs.

    Science.gov (United States)

    Gonzalez-Vicente, Agustin; Garvin, Jeffrey L

    2013-11-01

    Thick ascending limbs (TAL) reabsorb 30% of the filtered NaCl load. Na enters the cells via apical Na-K-2Cl cotransporters and Na/H exchangers and exits via basolateral Na pumps. Chronic angiotensin II (ANG II) infusion increases net TAL Na transport and Na apical entry; however, little is known about its effects on the basolateral Na pump. We hypothesized that in rat TALs Na pump activity is enhanced by ANG II-infusion, a model of ANG II-induced hypertension. Rats were infused with 200 ng·kg(-1)·min(-1) ANG II or vehicle for 7 days, and TAL suspensions were obtained. We studied plasma membrane Na pump activity by measuring changes in 1) intracellular Na (Nai) induced by ouabain; and 2) ouabain-sensitive oxygen consumption (QO2). We found that the ouabain-sensitive rise in Nai in TALs from ANG II-infused rats was 12.8 ± 0.4 arbitrary fluorescent units (AFU)·mg(-1)·min(-1) compared with only 9.9 ± 1.1 AFU·mg(-1)·min(-1) in controls (P Na pump expression, the number of Na pumps in the plasma membrane, or the affinity for Na. When furosemide (1.1 mg·kg(-1)·day(-1)) was coinfused with ANG II, no increase in plasma membrane Na pump activity was observed. We concluded that in ANG II-induced hypertension Na pump activity is increased in the plasma membrane of TALs and that this increase is caused by the chronically enhanced Na entry occurring in this model.

  17. Rescue of Na+ affinity in aspartate 928 mutants of Na+,K+-ATPase by secondary mutation of glutamate 314.

    Science.gov (United States)

    Holm, Rikke; Einholm, Anja P; Andersen, Jens P; Vilsen, Bente

    2015-04-10

    The Na(+),K(+)-ATPase binds Na(+) at three transport sites denoted I, II, and III, of which site III is Na(+)-specific and suggested to be the first occupied in the cooperative binding process activating phosphorylation from ATP. Here we demonstrate that the asparagine substitution of the aspartate associated with site III found in patients with rapid-onset dystonia parkinsonism or alternating hemiplegia of childhood causes a dramatic reduction of Na(+) affinity in the α1-, α2-, and α3-isoforms of Na(+),K(+)-ATPase, whereas other substitutions of this aspartate are much less disruptive. This is likely due to interference by the amide function of the asparagine side chain with Na(+)-coordinating residues in site III. Remarkably, the Na(+) affinity of site III aspartate to asparagine and alanine mutants is rescued by second-site mutation of a glutamate in the extracellular part of the fourth transmembrane helix, distant to site III. This gain-of-function mutation works without recovery of the lost cooperativity and selectivity of Na(+) binding and does not affect the E1-E2 conformational equilibrium or the maximum phosphorylation rate. Hence, the rescue of Na(+) affinity is likely intrinsic to the Na(+) binding pocket, and the underlying mechanism could be a tightening of Na(+) binding at Na(+) site II, possibly via movement of transmembrane helix four. The second-site mutation also improves Na(+),K(+) pump function in intact cells. Rescue of Na(+) affinity and Na(+) and K(+) transport by second-site mutation is unique in the history of Na(+),K(+)-ATPase and points to new possibilities for treatment of neurological patients carrying Na(+),K(+)-ATPase mutations. © 2015 by The American Society for Biochemistry and Molecular Biology, Inc.

  18. Characterization of Na+-linked and Na+-independent Cl-/HCO3- exchange systems in Chinese hamster lung fibroblasts

    International Nuclear Information System (INIS)

    Cassel, D.; Scharf, O.; Rotman, M.; Cragoe, E.J. Jr.; Katz, M.

    1988-01-01

    The PS120 variant of Chinese hamster lung fibroblasts which lacks Na + /H + exchange activity was used to investigate bicarbonate transport systems and their role in intracellular pH (pH/sub i/) regulation. When pH/sub i/ was decreased by acid load, bicarbonate caused pH/sub i/ increase and stimulated 36 Cl - efflux from the cells, both in a Na + -dependent manner. These results together with previous findings that bicarbonate stimulates 22 Na + uptake in PS120 cells demonstrate the presence of a Na + -linked Cl - /HCO 3 - exchange system. In cells with normal initial pH/sub i/, bicarbonate caused Na + -independent pH/sub i/ increase in Cl - -free solutions and stimulated Na + -independent 36 Cl - efflux, indicating that a Na + -independent Cl - /HCO 3 - exchanger is also present in the cell. Na + -linked and Na + -independent Cl - /HCO 3- exchange is apparently mediated by two distinct systems, since a [(tetrahydrofluorene-7-yl)oxy]acetic acid derivative selectively inhibits the Na + -independent exchanger. An additional distinctive features is a 10-fold lower affinity for chloride of the Na + -linked exchanger. The Na + -linked and Na + -independent Cl - /HCO 3 - exchange systems are likely to protect the cell from acid and alkaline load, respectively

  19. The two C-terminal tyrosines stabilize occluded Na/K pump conformations containing Na or K ions.

    Science.gov (United States)

    Vedovato, Natascia; Gadsby, David C

    2010-07-01

    Interactions of the three transported Na ions with the Na/K pump remain incompletely understood. Na/K pump crystal structures show that the extended C terminus of the Na,K-adenosine triphosphatase (ATPase) alpha subunit directly contacts transmembrane helices. Deletion of the last five residues (KETYY in almost all Na/K pumps) markedly lowered the apparent affinity for Na activation of pump phosphorylation from ATP, a reflection of cytoplasmic Na affinity for forming the occluded E1P(Na3) conformation. ATPase assays further suggested that C-terminal truncations also interfere with low affinity Na interactions, which are attributable to extracellular effects. Because extracellular Na ions traverse part of the membrane's electric field to reach their binding sites in the Na/K pump, their movements generate currents that can be monitored with high resolution. We report here electrical measurements to examine how Na/K pump interactions with extracellular Na ions are influenced by C-terminal truncations. We deleted the last two (YY) or five (KESYY) residues in Xenopus laevis alpha1 Na/K pumps made ouabain resistant by either of two kinds of point mutations and measured their currents as 10-mM ouabain-sensitive currents in Xenopus oocytes after silencing endogenous Xenopus Na/K pumps with 1 microM ouabain. We found the low affinity inhibitory influence of extracellular Na on outward Na/K pump current at negative voltages to be impaired in all of the C-terminally truncated pumps. Correspondingly, voltage jump-induced transient charge movements that reflect pump interactions with extracellular Na ions were strongly shifted to more negative potentials; this signals a several-fold reduction of the apparent affinity for extracellular Na in the truncated pumps. Parallel lowering of Na affinity on both sides of the membrane argues that the C-terminal contacts provide important stabilization of the occluded E1P(Na3) conformation, regardless of the route of Na ion entry into the

  20. The rapid-onset dystonia parkinsonism mutation D923N of the Na+, K+-ATPase alpha3 isoform disrupts Na+ interaction at the third Na+ site.

    Science.gov (United States)

    Einholm, Anja Pernille; Toustrup-Jensen, Mads S; Holm, Rikke; Andersen, Jens Peter; Vilsen, Bente

    2010-08-20

    Rapid-onset dystonia parkinsonism (RDP), a rare neurological disorder, is caused by mutation of the neuron-specific alpha3-isoform of Na(+), K(+)-ATPase. Here, we present the functional consequences of RDP mutation D923N. Relative to the wild type, the mutant exhibits a remarkable approximately 200-fold reduction of Na(+) affinity for activation of phosphorylation from ATP, reflecting a defective interaction of the E(1) form with intracellular Na(+). This is the largest effect on Na(+) affinity reported so far for any Na(+), K(+)-ATPase mutant. D923N also affects the interaction with extracellular Na(+) normally driving the E(1)P to E(2)P conformational transition backward. However, no impairment of K(+) binding was observed for D923N, leading to the conclusion that Asp(923) is specifically associated with the third Na(+) site that is selective toward Na(+). The crystal structure of the Na(+), K(+)-ATPase in E(2) form shows that Asp(923) is located in the cytoplasmic half of transmembrane helix M8 inside a putative transport channel, which is lined by residues from the transmembrane helices M5, M7, M8, and M10 and capped by the C terminus, recently found involved in recognition of the third Na(+) ion. Structural modeling of the E(1) form of Na(+), K(+)-ATPase based on the Ca(2+)-ATPase crystal structure is consistent with the hypothesis that Asp(923) contributes to a site binding the third Na(+) ion. These results in conjunction with our previous findings with other RDP mutants suggest that a selective defect in the handling of Na(+) may be a general feature of the RDP disorder.

  1. Jogos teatrais na escola pública

    Directory of Open Access Journals (Sweden)

    Ricardo Ottoni Vaz Japiassu

    1998-07-01

    Full Text Available O artigo apresenta os resultados parciais de pesquisa etnográfica que acompanha aspectos do desenvolvimento cultural de pré-adolescentes com a linguagem teatral em classe multisseriada, através do ensino regular de Teatro, em escola de ensino fundamental da rede pública estadual de São Paulo-SP. Os dados obtidos permitem afirmar que a linguagem cênica contribui na conscientização das novas possibilidades de significação da palavra na prática discursiva.The article shows partial results of ethnographic research in which kids are observed in their cultural development process with theater classes in public school education in São Paulo/Brazil. The data colected indicates that the use of theater games in school education helps students to be aware of a word’s new meaning possibilities in human comunication.

  2. Luz e tempo na melancolia I

    Directory of Open Access Journals (Sweden)

    Cláudio Soares Braga Furtado

    2009-12-01

    Full Text Available A comparação entre as artes possibilita figurar o tempo como elemento comum entre a gravura renascentista de Dürer, a escultura romana de Laocoonte e o conto de Guimarães Rosa. A partir da leitura dessas artes distantes em forma, meios, época e lugar, descobrem-se mistérios aludidos em sutis sinais, que, se ainda não despertos na consciência criativa, estimulam interpretações. O papel da luz como unificadora das entidades tempo/espaço restabelece o princípio clássico da ut pictura poesis na leitura moderna.

  3. NA62 experiment at CERN SPS

    Directory of Open Access Journals (Sweden)

    Kozhuharov Venelin

    2014-01-01

    Full Text Available The NA62 experiment at SPS is a continuation of the long standing CERN kaon physics program. The high statistics and the unprecedent precision allow to probe the Standard Model and test the description of the strong interactions at low energy. The final results on the the lepton universality test by measuring the ratio RK = Γ(K+ → e+ν/Γ(K+ → µ+ν and the study of the K± → π±γγ decay are presented. The major goal of the NA62 experiment is to perform a measurement of the Br(K+ → π+νν̄ with a precision of 10% in two years of data taking. The detector setup together with the analysis technique is described.

  4. O Personal Trainer na Perspectiva do Marketing

    Directory of Open Access Journals (Sweden)

    Cibele Biehl Bossle

    2011-03-01

    Full Text Available Esse estudo apresenta mapeamento das referências dedicadas à formação do personal trainer em bases de dados eletrônicas. Essa garimpagem revelou baixa produção científica sobre o assunto e mostrou que na literatura sobre personal trainer predominam livros com linguagem corrente no mundo dos negócios. Esses achados nos levaram a indagar sobre a força do discurso físico-empresarial, especialmente o marketing, na constituição desta ocupação profissional. Jeremy Rifkin, Zygmunt Bauman, Paula Sibilia e Denise Sant'Anna permitiram visualizar que o marketing dirigido ao personal trainer tem como tarefa reinventar, ressignificar e "repaginar" esta modalidade de serviço em nome da sobrevivência no disputado mercado da vida ativa.

  5. Algoritmo de lanczos na variedade de grassmann

    OpenAIRE

    Lopes, Ana Paula Ferreira Fernandes; Viamonte, Ana Júlia; Pascoal, António José

    2008-01-01

    O problema do cálculo de valores próprios, vectores próprios e subespaços invariantes está presente em áreas tão diversas como Engenharia, Física, Ciências de Computação e Matemática. Considerando a importância deste problema em tantas aplicações práticas, não é de surpreender que tenha sido e continue a ser objecto de intensa investigação, dando corpo a uma literatura muito vasta. Desenvolvemos um novo algoritmo de Lanczos na variedade de Grassmann. Este trabalho surgiu na ...

  6. Kaizen: Uma Metodologia Inovadora na Siderurgia

    Directory of Open Access Journals (Sweden)

    Hericson Estanislau Prata

    2017-04-01

    Full Text Available A racionalização do processo produtivo industrial, por meio da redução dos desperdícios e da modernização do processo produtivo, com a adoção do Sistema Toyota de Produção (Produção Enxuta, tem sido adotada por uma parte importante das indústrias no mundo. O objetivo deste artigo é descrever essa metodologia empregada pelo grupo de melhoria de fase intensiva adotado na Vallourec Tubos do Brasil S.A. Como resultado, verificou-se que o processo utilizado para a implantação de mudanças em curto prazo foi a semana intensiva, também conhecida como evento Kaizen na indústria automotiva.

  7. The NA60 experiment readout architecture

    CERN Document Server

    Floris, M; Usai, G L; David, A; Rosinsky, P; Ohnishi, H

    2004-01-01

    The NA60 experiment was designed to identify signatures of a new state of matter, the Quark Gluon Plasma, in heavy-ion collisions at the CERN Super Proton Synchroton. The apparatus is composed of four main detectors: a muon spectrometer (MS), a zero degree calorimeter (ZDC), a silicon vertex telescope (VT), and a silicon microstrip beam tracker (BT). The readout of the whole experiment is based on a PCI architecture. The basic unit is a general purpose PCI card, interfaced to the different subdetectors via custom mezzanine cards. This allowed us to successfully implement several completely different readout protocols (from the VME like protocol of the MS to the custom protocol of the pixel telescope). The system was fully tested with proton and ion beams, and several million events were collected in 2002 and 2003. This paper presents the readout architecture of NA60, with particular emphasis on the PCI layer common to all the subdetectors. (16 refs).

  8. Urgências reprodutivas na cadela

    OpenAIRE

    Costa, Teresa Isabel Rodrigues da

    2010-01-01

    Dissertação de Mestrado Integrado em Medicina Veterinária As urgências reprodutivas ocorrem com frequência na prática clínica, estando o seu desfecho favorável associado a um diagnóstico e intervenção céleres. Na cadela, consideram-se urgências reprodutivas a distócia, a piómetra, o prolapso uterino, a torção uterina, a tetania puerperal, a metrite e a mastite. Esta dissertação tem por base a análise dos dados referentes à casuística de urgências reprodutivas em cadelas veri...

  9. NA35: sulphur-gold collision

    CERN Multimedia

    1991-01-01

    In this image the real particles produced by the collision of a 6400 GeV sulphur ion with a gold target can be seen as they pass through a streamer chamber. Streamer chambers consist of a gas chamber through which a strong pulsed electric field is passed, creating sparks as a charged particle passes through it. The NA35 experiment, which was in operation in the 1980s, was part of CERN's ongoing heavy ion project.

  10. New NA22 results on correlations

    International Nuclear Information System (INIS)

    De Wolf, E.A.

    1993-01-01

    Recent NA22 results from π + p and K + p inelastic interactions at √s = 22 GeV on invariant-mass and Q 2 -dependence of two- and three-particle factorial cumulants are discussed in relation to earlier intermittency studies. The absence of Bose-Einstein type correlations among identical particles, and too large resonance production rates, are responsible for the strong disagreements of models with intermittency data. 6 figs., 17 refs

  11. O legado grego na terminologia gramatical brasileira

    Directory of Open Access Journals (Sweden)

    Maria Helena de Moura Neves

    2011-12-01

    Full Text Available Este estudo tem como objetivo pesquisar a existência de um legado grego terminológico na organização gramatical brasileira, considerando que a gramática incipiente grega é a fonte da nossa gramática, por via da gramática latina, e que o recorte de campo que ela preparou é um ponto de referência para o estudo da evolução do pensamento ocidental sobre a linguagem. A orientação teórico-metodológica se assenta na Linguística Histórica, na linha que orientou a ampla pesquisa sobre a emergência da gramática no Ocidente que constitui a fonte das informações que aqui se organizam (NEVES, 2005. As reflexões dirigem-se especialmente para o exame da nomenclatura, entendendo que ela mapeia conceptualmente o conjunto das posições assumidas, e em geral mantidas, que merecem apreciação. Entre outras coisas o exame opôs: termos gregos legados na corrente contínua do pensamento gramatical a termos gregos introduzidos posteriormente; termos transliterados do grego a termos decalcados da tradução latina. Além disso, verificaram-se casos de alteração de nome com manutenção de conceito, e casos de alteração de conceito para um nome conservado. De todo modo, o exame da nomenclatura revela a indiscutível existência de um legado grego à organização da gramática portuguesa.

  12. Isovector magnetic dipole transition in 22Na

    International Nuclear Information System (INIS)

    Fifield, L.K.; Poletti, A.R.; Radford, D.C.

    1980-01-01

    The mean life of the 657 keV 0 + , T = 1 level in 22 Na for the radiative decay to the 583 keV 1 + , T = 0 level has been measured as tau = (27.1 +- 1.2)ps. A modification of the recoil-distance method (RDM) was used. In addition, the mean life of the 891 keV level in the same nucleus was remeasured to give tau = (14.1 +- 0.5)ps. (author)

  13. Prototype calorimeters for the NA3 experiment

    CERN Multimedia

    1975-01-01

    The NA3 Experiment was set-up on the North Area of the SPS by the CERN/ Ecole Polytechnique/College de France/ Orsay/Saclay Collaboration, to study high transverse momentum leptons and hadrons from hadron collisions. The calorimeters measured the energy of hadrons (prototype on the right) and leptons (prototype on the left). They used a new type of plastic scintillator (plexipop). (see CERN Courier of November 1975) energy (prototype on the right)

  14. The NA48 liquid krypton calorimeter

    CERN Document Server

    Gorini, B

    1997-01-01

    The NA48 collaboration goal is to measure the CP violation parameter Re(ɛl/ɛ) at the level of 2 × 10−4. The neutral Kaon decays will be reconstructed by an electromagnetic liquid Krypton calorimeter with fine granularity and a volume almost totally sensible, to obtain excellent position and energy resolution, as well as time resolution. A description of the detector, results from tests of a prototype and the status of the final calorimeter are reported.

  15. Maendeleo ya Fasihi ya Kiswahili ya Watoto nchini Tanzania na ...

    African Journals Online (AJOL)

    Fasihi ya Kiswahili ya watoto kama taaluma haina muda mrefu katika historia ya fasihi ya Kiswahili. Ikilinganishwa na fasihi ya watu wazima ambayo ilianza muda mrefu, na pia tafiti nyingi kufanyika katika mataifa mengi, fasihi ya watoto inaonekana kuwa imetelekezwa kwa muda mrefu kutokana na kutokupewa umuhimu ...

  16. Dhima za Mbinu Linganishi katika Kuhusisha Lugha na Lahaja ...

    African Journals Online (AJOL)

    Lengo la makala hii ni kujadili dhima za Mbinu Linganishi katika kuhusisha lugha na lahaja. Data za makala hii zilikusanywa kwa kutumia mbinu mbalimbali ambazo ni usaili, ushuhudiaji, hojaji na majadiliano katika majopo. Utafiti ulifanyika Tanzania Bara hususan Mkoani Mtwara na Tanzania Visiwani katika maeneo ya ...

  17. VARSTVO DOSTOJANSTVA DELAVCA IN JAVNEGA USLUŽBENCA NA DELU

    OpenAIRE

    Trstenjak, Jasna

    2011-01-01

    V magistrski nalogi sem želela proučiti varstvo dostojanstva delavca in javnega uslužbenca na delu, saj menim, da je to ključen dejavnik v delovnem razmerju vsakega posameznika, prav tako ima neposreden vpliv na konkurenčno sposobnost kot tudi na stroške dela, tako v javnem kot v zasebnem sektorju.

  18. Efficacy of 22Na turnover in ecopbysiological studies of carnivores

    African Journals Online (AJOL)

    Efficacy of 22Na turnover in ecopbysiological studies of carnivores. loS. Wilkinson and J.D. Skinner*. Mammal Research Institute, University of Pretoria, Pretoria, 0002 Republic of South Africa. Received 8 December 1986; accepted 11 August 1987. 22Na turnover rates gave overestimates of mean 23Na intake in both ...

  19. UREDITEV SPOLNEGA NADLEGOVANJA NA DELOVNEM MESTU V REPUBLIKI SLOVENIJI

    OpenAIRE

    Golavšek, Nastja

    2009-01-01

    V diplomski nalogi je predstavljena problematika spolnega nadlegovanja na delovnem mestu. Spolno nadlegovanje je nezaželeno ravnanje spolne narave ali drugo ravnanje, temelječe na spolu, ki ogroža dostojanstvo žensk in moških na delovnem mestu

  20. Muundo wa Mashairi katika Diwani ya Mnyampala (1965) na Nafasi ...

    African Journals Online (AJOL)

    Makala hii pia inadadisi namna mbinu za kimuundo zilivyofanikisha usawiri na ubainishaji wa falsafa ya mtunzi kuhusu ushairi wa Kiswahili na nafasi ya ushairi katika jamii. Makala imeanza kwa kugusia usuli wa historia ya ushairi wa Kiswahili, historia fupi ya maisha ya Mathias Mnyampala na nadharia yake kuhusu ...

  1. Explosive phenomena in heavily irradiated NaCl

    NARCIS (Netherlands)

    denHartog, HW; Vainshtein, DI; Matthews, GE; Williams, RT

    1997-01-01

    In heavily irradiated NaCl crystals explosive phenomena can be initiated during irradiation or afterwards when samples are heated to temperatures between 100 and 250 degrees C. During irradiation of NaCl Na and Cl-2 precipitates and void structures are produced along with the accumulation of stored

  2. NaI(Tl) response functions

    International Nuclear Information System (INIS)

    Vega C, H. R.; Ortiz R, J. M.; Benites R, J. L.; De Leon M, H. A.

    2015-09-01

    The response functions of a NaI(Tl) detector have been estimated using Monte Carlo methods. Response functions were calculated for monoenergetic photon sources (0.05 to 3 MeV). Responses were calculated for point-like sources and for sources distributed in Portland cement cylinders. The responses were used to calculate the efficiency functions in term of photon energy. Commonly, sources used for calibration are point-like, and eventually sources to be measured have different features. In order to use the calibrated sources corrections due to solid angle, self-absorption and scattering, must be carried out. However, some of these corrections are not easy to perform. In this work, the calculated responses were used to estimate the detector efficiency of point-like sources, and sources distributed in Portland type cement. Samples of Portland paste were prepared and were exposed to photoneutrons produced by a 15 MV linac. Some of the elements in the cement were activated producing γ-emitting radionuclides that were measured with a NaI(Tl) gamma-ray spectrometer, that was calibrated with point-like sources. In order to determine the specific activity in the induced radioisotopes calculated efficiencies were used to make corrections due to the differences between the solid angle, photon absorption and photon scattering in the point-like calibration sources and the sources distributed in cement. During the interaction between photoneutrons and the cement samples three radioisotopes were induced: 56 Mn, 24 Na, and 28 Al. (Author)

  3. Cultura Política na Antiguidade

    Directory of Open Access Journals (Sweden)

    José Petrúcio Farias Júnior

    2009-06-01

    Full Text Available

    Pretendemos discutir nesse artigo algumas implicações do termo cultura política na Antiguidade, especificamente, na sociedade romana imperial. Dessa forma, acreditamos que as considerações que apresentaremos a seguir contribuam para reflexão da utilização desse termo, produto das investigações contemporâneas, sobre os estudos das sociedades antigas. Para a historiadora Profa. Dra. Margarida Maria de Carvalho, tais reflexões representam ainda uma lacuna na historiografia concernente a essa temática. Isso posto, discorreremos, inicialmente, sobre o conceito de cultura e seus desdobramentos para, em seguida, refletirmos sobre o viés interpretativo que fundamenta estudos históricos que se desenvolvem sob o beneplácito da linha de pesquisa intitulada História e Cultura Política.

  4. NaI Detector Network at Aragats

    International Nuclear Information System (INIS)

    Avakyan, Karen; Arakelyan, Karen; Chilingarian, Ashot; Daryan, Ara; Kozliner, Lev; Mailyan, Bagrat; Hovsepyan, Gagik; Pokhsraryan, David; Sargsyan, David

    2013-01-01

    The Aragats Space Environmental Center (ASEC) provides monitoring of different species of secondary cosmic rays and consists of two high altitude research stations on Mt. Aragats in Armenia. Along with solar modulation effects, ASEC detectors register several coherent enhancements associated with thunderstorm activity. The experimental techniques used allowed for the first time to simultaneously measure fluxes of the electrons, muons, gamma rays, and neutrons correlated with thunderstorm activity. Ground-based observations by a complex of surface particle detectors, measuring in systematically and repeatable fashion, gamma quanta, electrons, muons and neutrons from atmospheric sources are necessary for proving the theory of particle acceleration and multiplication during thunderstorms. Energy spectra and correlations between fluxes of different particles, measured on Earth's surface address the important issues of research of the solar modulation effects and the atmospheric high-energy phenomena. In May 26 2011, launched 5 NaI(Tl) (thallium-doped sodium iodide) scintillation detectors and 1 plastic one in the new ASEC laboratory on Aragats to detect low energy gamma rays from the thunderclouds and short particle bursts. Including NaI(Tl) detectors in ASEC detectors system is of great importance for investigation thunderstorm phenomena because NaI(Tl) detectors have high efficiency of gamma ray detecting in comparison with plastic ones.

  5. NA64 Search for Dark Photons

    CERN Document Server

    Shiakas, Christos

    2017-01-01

    The NA64 experiment, known as P348 before official approval, was proposed to the CERN SPSC on January 2014 with main goal the search for the following decay modes A′ → invisible A′ → e−e+ (1) In March 2016 P348 was granted approval by the CERN Research Board and received the title NA64. Since having been promoted, the experiment has been conducting the searches the searches for the processes mentioned above at the CERN SPS. NA64 is a fixed target experiment which utilizes the active beam dump. The detection of rare processes is based on the missing energy techniques. Such techniques are used for particles whose interaction with the detector is very small, so that they escape the detection and carry away some energy. A significant missing energy in the experiment means that such particles are produced. The method of the search for the A′ → invisible decay is as follows. If the A′ exists it could be produced via the kinetic mixing with bremsstrahlung photons in the reaction of high-energy elec...

  6. Experimental Study of Na based Titanium Nanofluid-Water Reaction

    Energy Technology Data Exchange (ETDEWEB)

    Park, Gunyeop; Kim, Soo Jae; Baek, Jehyun; Kim, Hyun Soo; Oh, Sun Ryung; Park, Hyun Sun; Kim, Moo Hwan [POSTECH, Pohang (Korea, Republic of)

    2015-10-15

    In KALIMER-600, a sodium-cooled fast reactor designed by KAERI, thermal energy is transported from high-temperature liquid Na (526 .deg. C at 0.1 MPa) to low temperature water (230 .deg. C at - 19.5 MPa) through a heat exchanger. If any leakage or rupture occurs during the operation of this heat exchanger, highly pressurized liquid water can penetrate into the liquid Na channels; this contact should instantly cause SWR. As reaction continues, liquid water is soon vaporized by pressure drop and huge amount of reaction heat. This generated water vapor expands large reaction area and increases sodium-water vapor reaction process. Therefore, the rapid generation of reaction product (like H{sub 2}) and water vapor increases the system pressure that can cause the system failure in SFR. To reduce this strong chemical reaction phenomena between Na and water, some we have focused on suppressing the chemical reactivity of liquid Na by dispersing nanoparticles (NPs). For the real application of NaTiNF, the pressure change induced by NaTiNF-water reaction is compared with Na-water reaction in the present study. NaTiNF contains 100nm of Ti NPs at 0.2 vol. %. The reaction rate of NaTiNF-water reaction is also investigated as reaction temperature increases. Sodium-water vapor reaction (SVR) will occur when an SWR accident occurs in SFR. In this manner, NaTiNF-water vapor reaction is experimentally performed for ensuring the suppression of chemical reactivity of NaTiNF in contact with water vapor. In the basic step for reducing risk of an SWR in SFR, we have experimentally verified the suppressed chemical reactivity of liquid sodium using Ti NPs through SWR and SVR experiments. In SWR, Na based titanium nanofluid (NaTiNF) shows lower pressure change than Na. As T{sub R} increases, P{sub max} in Na-water reaction increases while NaTiNF does not. The reaction rate of NaTiNF shows twice slower than that of Na. In SVR, NaTiNF shows slower temperature increase than Na. The distinct

  7. Route, mechanism, and implications of proton import during Na+/K+ exchange by native Na+/K+-ATPase pumps

    Science.gov (United States)

    Vedovato, Natascia

    2014-01-01

    A single Na+/K+-ATPase pumps three Na+ outwards and two K+ inwards by alternately exposing ion-binding sites to opposite sides of the membrane in a conformational sequence coupled to pump autophosphorylation from ATP and auto-dephosphorylation. The larger flow of Na+ than K+ generates outward current across the cell membrane. Less well understood is the ability of Na+/K+ pumps to generate an inward current of protons. Originally noted in pumps deprived of external K+ and Na+ ions, as inward current at negative membrane potentials that becomes amplified when external pH is lowered, this proton current is generally viewed as an artifact of those unnatural conditions. We demonstrate here that this inward current also flows at physiological K+ and Na+ concentrations. We show that protons exploit ready reversibility of conformational changes associated with extracellular Na+ release from phosphorylated Na+/K+ pumps. Reversal of a subset of these transitions allows an extracellular proton to bind an acidic side chain and to be subsequently released to the cytoplasm. This back-step of phosphorylated Na+/K+ pumps that enables proton import is not required for completion of the 3 Na+/2 K+ transport cycle. However, the back-step occurs readily during Na+/K+ transport when external K+ ion binding and occlusion are delayed, and it occurs more frequently when lowered extracellular pH raises the probability of protonation of the externally accessible carboxylate side chain. The proton route passes through the Na+-selective binding site III and is distinct from the principal pathway traversed by the majority of transported Na+ and K+ ions that passes through binding site II. The inferred occurrence of Na+/K+ exchange and H+ import during the same conformational cycle of a single molecule identifies the Na+/K+ pump as a hybrid transporter. Whether Na+/K+ pump–mediated proton inflow may have any physiological or pathophysiological significance remains to be clarified. PMID

  8. Route, mechanism, and implications of proton import during Na+/K+ exchange by native Na+/K+-ATPase pumps.

    Science.gov (United States)

    Vedovato, Natascia; Gadsby, David C

    2014-04-01

    A single Na(+)/K(+)-ATPase pumps three Na(+) outwards and two K(+) inwards by alternately exposing ion-binding sites to opposite sides of the membrane in a conformational sequence coupled to pump autophosphorylation from ATP and auto-dephosphorylation. The larger flow of Na(+) than K(+) generates outward current across the cell membrane. Less well understood is the ability of Na(+)/K(+) pumps to generate an inward current of protons. Originally noted in pumps deprived of external K(+) and Na(+) ions, as inward current at negative membrane potentials that becomes amplified when external pH is lowered, this proton current is generally viewed as an artifact of those unnatural conditions. We demonstrate here that this inward current also flows at physiological K(+) and Na(+) concentrations. We show that protons exploit ready reversibility of conformational changes associated with extracellular Na(+) release from phosphorylated Na(+)/K(+) pumps. Reversal of a subset of these transitions allows an extracellular proton to bind an acidic side chain and to be subsequently released to the cytoplasm. This back-step of phosphorylated Na(+)/K(+) pumps that enables proton import is not required for completion of the 3 Na(+)/2 K(+) transport cycle. However, the back-step occurs readily during Na(+)/K(+) transport when external K(+) ion binding and occlusion are delayed, and it occurs more frequently when lowered extracellular pH raises the probability of protonation of the externally accessible carboxylate side chain. The proton route passes through the Na(+)-selective binding site III and is distinct from the principal pathway traversed by the majority of transported Na(+) and K(+) ions that passes through binding site II. The inferred occurrence of Na(+)/K(+) exchange and H(+) import during the same conformational cycle of a single molecule identifies the Na(+)/K(+) pump as a hybrid transporter. Whether Na(+)/K(+) pump-mediated proton inflow may have any physiological or

  9. Growth mechanism of NaClO 3 and NaBrO 3 crystals from aqueous ...

    Indian Academy of Sciences (India)

    A study of growth rates of NaClO3 and NaBrO3 has been carried out using a small growth cell by in situ observation. Normal growth rates of {100} faces of NaClO3 and {111} faces of NaBrO3 along ⟨ 110 ⟩ direction are measured under relatively high supersaturation ranging from 3–8%. In the initial stages of growth, {100}, ...

  10. Plant Defensins NaD1 and NaD2 Induce Different Stress Response Pathways in Fungi

    Directory of Open Access Journals (Sweden)

    Peter M. Dracatos

    2016-09-01

    Full Text Available Nicotiana alata defensins 1 and 2 (NaD1 and NaD2 are plant defensins from the ornamental tobacco that have antifungal activity against a variety of fungal pathogens. Some plant defensins interact with fungal cell wall O-glycosylated proteins. Therefore, we investigated if this was the case for NaD1 and NaD2, by assessing the sensitivity of the three Aspergillus nidulans (An O-mannosyltransferase (pmt knockout (KO mutants (An∆pmtA, An∆pmtB, and An∆pmtC. An∆pmtA was resistant to both defensins, while An∆pmtC was resistant to NaD2 only, suggesting NaD1 and NaD2 are unlikely to have a general interaction with O-linked side chains. Further evidence of this difference in the antifungal mechanism was provided by the dissimilarity of the NaD1 and NaD2 sensitivities of the Fusarium oxysporum f. sp. lycopersici (Fol signalling knockout mutants from the cell wall integrity (CWI and high osmolarity glycerol (HOG mitogen-activated protein kinase (MAPK pathways. HOG pathway mutants were sensitive to both NaD1 and NaD2, while CWI pathway mutants only displayed sensitivity to NaD2.

  11. Response of saliva Na/K ratio to changing Na supply of lactating cows under tropical conditions

    NARCIS (Netherlands)

    Thiangtum, Wandee; Schonewille, J Thomas; Verstegen, Martin Wa; Arsawakulsudhi, Supot; Rukkwamsuk, Theera; Hendriks, Wouter H

    BACKGROUND: Factorial determination of the sodium (Na) requirement of heat-stressed lactating cows is hindered by accurate estimates of the Na losses through sweat. Direct studies, therefore, may be needed requiring information on the time course of healthy animals to become Na depleted and the

  12. Response of saliva Na/K ratio to changing Na supply of lactating cows under tropical conditions

    NARCIS (Netherlands)

    Thiangtum, Wandee; Schonewille, Thomas J.; Verstegen, Martin W.A.; Arsawakulsudhi, Supot; Rukkwamsuk, Theera; Hendriks, Wouter H.

    2017-01-01

    BACKGROUND: Factorial determination of the sodium (Na) requirement of heat-stressed lactating cows is hindered by accurate estimates of the Na losses through sweat. Direct studies, therefore, may be needed requiring information on the time course of healthy animals to become Na depleted and the

  13. Polarization and collision velocity dependence of associative ionization in cold Na (3p)-Na(3p) collisions

    NARCIS (Netherlands)

    Meijer, H.A.J.

    1990-01-01

    We studied the polarization dependence of the associative ionization (AI) process Na(3p) + Na(3p) → Na2+ at collision velocities between 100 and 700 m/s (5 and 200 K), using linearly and circularly polarized light for the excitation. We found that the polarization dependence varies strongly in the

  14. Reactions of metal oxides with molten NaPO3 + NaCl mixtures

    International Nuclear Information System (INIS)

    Kovarskaya, E.N.; Mityakhina, V.S.; Rodionov, Yu.I.; Silin, M.Yu.

    1988-01-01

    We consider the dissolution mechanism for iron (III), europium(III), and tin(IV) oxides in molten NaPO 3 + NaCl that are responsible for the peak solubilities. We chose Fe 2 O 3 as the basic material since this occurs in large amounts around damaged metal structures in rock salt mines in a proposed zone for storing vitrified radioactive wastes. Solubility measurement and paper chromatography show that Fe 2 O 3 dissolves in molten NaPO 3 + NaCl in air by reaction with the solvent to give double iron and sodium diphosphates and monophosphates in accordance with the initial solution-in-the-melt composition, the degree of equilibration, and the temperature. The elevated solubilities for initial NaCl contents close to 30 mole % are due to sodium triphosphates and tricyclophosphates present in these melts. Moessbauer spectroscopy confirms that double iron, europium and tin diphosphates and monophosphates containing sodium occur in these chloride-polyphosphate melts

  15. MOBILNO POSLOVANJE NA PRIMERU UPORABE MICROSOFT DYNAMICS CRM

    OpenAIRE

    Duh, Tamara

    2016-01-01

    Hitro razvijajoči se svet nas spodbuja k hitremu reagiranju na novosti, ki se pojavljajo na trgu. Prav zaradi tega je danes zelo pomembno upravljati z mobilnimi napravami, da se lahko hitro in brez težav soočimo z morebitnimi težavami oz. zagatami. Prav iz tega razloga je mobilno poslovanje ena izmed inovativnih rešitev, ki ljudem omogoča seznanjenost z informacijami na vsakem koraku in omogoča hiter odziv na spremembe. Prav ta rešitev omogoča podjetjem, da so konkurenčna in hkrati lahko hitr...

  16. Predstave o seksu u filmovima na temu postapokalipse

    Directory of Open Access Journals (Sweden)

    Ana Banić-Grubišić

    2016-03-01

    Full Text Available Rad se bavi načinima predstavljanja seksualnih odnosa u filmovima na temu postapokalipse. Razmatraju se različiti oblici/vrste seksualnih veza, koje se javljaju u postkataklizmičnom okruženju, u odnosu na dva tipa zajednica/društava koja nastaju nakon kraja sveta. Ti filmovi pokazuju koliko je ideja o nagonskoj, prirodnoj, biološkoj seksualnosti raširena u popularnoj imaginaciji – seks je u postapokalipsi predstavljen kao pokretačka sila, na isti način kao što je to i glad.

  17. Usando a antimatéria na medicina moderna

    OpenAIRE

    Machado,A.C.B.; Pleitez,V.; Tijero,M.C.

    2006-01-01

    Neste artigo, fazemos uma breve exposição de como um dos conceitos fundamentais da física moderna, a existência de antimatéria, tem aplicação na medicina, na chamada tomografia por emissão de pósitrons (PET na sigla em inglês). Ela consiste na produção de imagens tomográficas digitais do organismo que são obtidas pela detecção da radiação produzida na aniquilação do pósitron com o elétron.

  18. Imenovanje jednonitnih homopolimera i kopolimera na osnovi podrijetla (I. dio

    Directory of Open Access Journals (Sweden)

    Vida Jarm

    2018-04-01

    Full Text Available Prethodne IUPAC-ove preporuke imenovanja (nomenklature jednonitnih polimera na osnovi podrijetla (NOP odnosile su se uglavnom na kopolimere, nelinearne polimere, združene polimere i generičke polimere. Pravila navedena u ovim preporukama omogućuju jasnije i preciznije imenovanje polimera na osnovi podrijetla, kako homopolimera tako i kopolimera. Prikazani sveobuhvatni sustav imenovanja polimera na osnovi podrijetla prihvatljiva je alternativa sustavu imenovanja polimera na osnovi strukture. Zbog raširene i česte uporabe dodatno su opisane i preporuke za uporabu uvriježenih imena polimera.

  19. Novel regulation of cardiac Na pump via phospholemman.

    Science.gov (United States)

    Pavlovic, Davor; Fuller, William; Shattock, Michael J

    2013-08-01

    As the only quantitatively significant Na efflux pathway from cardiac cells, the Na/K ATPase (Na pump) is the primary regulator of intracellular Na. The transmembrane Na gradient it establishes is essential for normal electrical excitability, numerous coupled-transport processes and, as the driving force for Na/Ca exchange, thus setting cardiac Ca load and contractility. As Na influx varies with electrical excitation, heart rate and pathology, the dynamic regulation of Na efflux is essential. It is now widely recognized that phospholemman, a 72 amino acid accessory protein which forms part of the Na pump complex, is the key nexus linking cellular signaling to pump regulation. Phospholemman is the target of a variety of post-translational modifications (including phosphorylation, palmitoylation and glutathionation) and these can dynamically alter the activity of the Na pump. This review summarizes our current understanding of the multiple regulatory mechanisms that converge on phospholemman and govern NA pump activity in the heart. The corrected Fig. 4 is reproduced below. The publisher would like to apologize for any inconvenience caused. [corrected]. Copyright © 2013. Published by Elsevier Ltd.

  20. Synthesis of zeolites Na-A and Na-X from tablet compressed and calcinated coal fly ash

    Science.gov (United States)

    Hu, Tao; Gao, Wenyan; Liu, Xin; Zhang, Yifu; Meng, Changgong

    2017-10-01

    Zeolites Na-A and Na-X are important synthetic zeolites widely used for separation and adsorption in industry. It is of great significance to develop energy-efficient routines that can synthesize zeolites Na-A and Na-X from low-cost raw materials. Coal fly ash (CFA) is the major residue from the combustion of coal and biomass containing more than 85% SiO2 and Al2O3, which can readily replace the conventionally used sodium silicate and aluminate for zeolite synthesis. We used Na2CO3 to replace the expensive NaOH used for the calcination of CFA and showed that tablet compression can enhance the contact with Na2CO3 for the activation of CFA through calcination for the synthesis of zeolites Na-A and Na-X under mild conditions. We optimized the control variables for zeolite synthesis and showed that phase-pure zeolite Na-A can be synthesized with CFA at reactant molar ratio, hydrothermal reaction temperature and reaction time of 1.3Na2O: 0.6Al2O3: 1SiO2: 38H2O at 80°C for 6 h, respectively, while phase-pure zeolite Na-X can be synthesized at 2.2Na2O: 0.2Al2O3: 1SiO2: 88H2O at 100°C for 8 h, respectively. The composition, morphology, specific surface area, vibration spectrum and thermogravimetry of synthesized Na-A and Na-X were further characterized.

  1. Synthesis of Na-A and/or Na-X zeolite/porous carbon composites from carbonized rice husk

    International Nuclear Information System (INIS)

    Katsuki, Hiroaki; Komarneni, Sridhar

    2009-01-01

    Na-A and/or Na-X zeolite/porous carbon composites were prepared under hydrothermal conditions by NaOH dissolution of silica first from carbonized rice husk followed by addition of NaAlO 2 and in situ crystallization of zeolites i.e., using a two-step process. When a one-step process was used, both Na-A and Na-X zeolites crystallized on the surface of carbon. Na-A or Na-X zeolite crystals were prepared on the porous carbonized rice husk at 90 deg. C for 2-6 h by changing the SiO 2 /Al 2 O 3 , H 2 O/Na 2 O and Na 2 O/SiO 2 molar ratios of precursors in the two-step process. The surface area and NH 4 + -cation exchange capacity (CEC) of Na-A zeolite/porous carbon were found to be 171 m 2 /g and 506 meq/100 g, respectively, while those of Na-X zeolite/porous carbon composites were 676 m 2 /g and 317 meq/100 g, respectively. Na-A and Na-X zeolites are well-known microporous and hydrophilic materials while carbonized rice husk was found to be mesoporous (pores of ∼3.9 nm) and hydrophobic. These hybrid microporous-mesoporous and hydrophilic-hydrophobic composites are expected to be useful for decontamination of metal cations as well as organic contaminants simultaneously. - Graphical Abstract: Novel Na-X zeolite/porous carbon composite.

  2. Recovery of the heavy elements by NaY AND NaZSM-5 sorbant materials

    International Nuclear Information System (INIS)

    Nibou, D.; Lebail, S.

    1997-04-01

    Porous sorbants as zeolites have a several applications in differents fiels: industrial gas purification, catalysis, transformation hydrocarbures prosesses and exchange ions. The hiogh capacity to exchange their cations with those of aqueous solutions was known (1). Since the accession of synthetic zeolites, these silicates have invaded the market and the firstindustrial applications were in exchange field. Studies at Battelle Northwest in Rchland, Washington have shown that zeolites may be used in treatment of radioactive wastes (2). The used method for storing the isotopes is based on selective removal by ion exchange. Clinoptilolite, zeolite (modernite), NaA, and AW-500 have been used. In this context, the present work deals with the recovery of heavy metals like lead and uranium using some microporous materials. The obtained results show that NaY faujasite and NaZSM-5 of the FAU- and MFI-type structure respectively are very effective in removing these elements from waste water

  3. Reaction of metal oxides with molten mixtures NaPO3+NaCl

    International Nuclear Information System (INIS)

    Kovarskaya, E.N.; Mityakhina, V.S.; Rodionov, Yu.I.; Silin, M.Yu.

    1988-01-01

    By methods of solubility determination and paper chromatography it is shown, that Fe 2 O 3 solution in NaPO 3 +NaCl melts in the air relizes due to its chemical interaction with solvent resulting in formation of iron and sodium binary di- and monophosphates depending on melt-solvent initial composition, its attainment of equilibrium state and experiment temperature. It is established, that oxides increased solubility in melts with NaCl initial content ∼30 mol.% is specified by sodium tri- and tricyclophosphates presence in the melts. On this basis of NGR-spectroscopy data the presence of iron, europium, tin and sodium binary di- and monophosphates in some chloride-polyphosphate melts is confirmed

  4. NA48 experiment : view along the NA48 beamline with the detector in the distance.

    CERN Multimedia

    Hans Taureg

    1996-01-01

    Photo 02: Side view of the NA48 experiment showing the LKR calorimeter cryostat No one is sure why the Universe wound up the way it has: all matter and no antimatter. According to prevailing theories, the early universe had equal amounts of matter and antimatter. To see what might be missing from the theories, physicists search for the rare cases in which matter and antimatter behave differently. One such imbalance, called direct CP violation, showed up in the NA 31 experiment at CERN. The results from this experiment, first presented in 1993, showed that when K mesons and their antimatter cousins decay, they show a slight preference for matter over antimatter. Later experiments with neutral K mesons, including NA48 at CERN and KTeV at Fermilab in the United States, showed direct CP violation is real.

  5. Erythrocyte Na+/K+ ATPase activity measured with sup 23 Na NMR

    Energy Technology Data Exchange (ETDEWEB)

    Ouwerkerk, R.; van Echteld, C.J.; Staal, G.E.; Rijksen, G. (University Hospital, Utrecht (Netherland))

    1989-11-01

    A {sup 23}Na NMR assay for measurement of erythrocyte Na+/K+ ATPase activity is presented. Using the nonpermeant shift reagent dysprosium tripolyphosphate the signals of intra- and extracellular sodium are separated, enabling measurement of sodium fluxes nondestructively, without the need to physically separate the cells from their environment. By increasing membrane permeability with nystatin we have shown that the assay allows the detection of differences in membrane permeability. With low doses of nystatin the ouabain-sensitive sodium flux increased more than twofold. With high doses of nystatin the Na+/K+ pump could not prevent an almost total equilibration of intra- and extracellular sodium. All sodium that entered the cells remained NMR visible, proving that sodium influx can be measured quantitatively. {sup 31}P NMR spectra taken before and after the assay revealed a slight acidification of the cells and no significant change in ATP concentration. No evidence of Dy3+ entering the cell was observed.

  6. Energy levels of the single excited states in NaI and Na-like ions

    International Nuclear Information System (INIS)

    El-Sherbini, T.M.; Wahby, A.S.

    1987-08-01

    Energy levels of the single excited 1s 2 2s 2 2p 6 ns( 2 S), 1s 2 2s 2 2p 6 mp( 2 P), 1s 2 2s 2 2p 6 md( 2 D) and 1s 2 2s 2 2p 6 nf( 2 F); n=4-7, m=3-6 states for NaI and Na-like ions are calculated using the one configuration Hartree-Fock method. Good agreement is obtained between our results for the higher members of the NaI sequence and previous data from photo-absorption and beam foil experiments. (author). 11 refs, 3 figs, 9 tabs

  7. Na+-K+ pump in chronic renal failure

    International Nuclear Information System (INIS)

    Deepak, K.; Kahn, T.

    1987-01-01

    This review summarizes the evidence for the defect in Na + -K + pump in chronic renal failure, considers the role of various factors in causing this defect, and discusses the clinical implications thereof. Intracellular Na is elevated in erythrocytes, leukocytes, and muscle cells from some patients with chronic renal failure (CRF). Recent evidence suggest that this elevation of cell Na may be, in large part, a consequence of decreased number of Na + -K + pump units per cell. Maintenance dialysis over a period of weeks ameliorates the defect in intracellular Na + , and this improvement is contemporaneous with an increase in the number of Na + -K + pump sites per cell. In erythrocytes with normal cell Na + , acute hemodialysis increases the rate of 22 Na + and 42 K + transport. Many factors such as the presence of retained toxic metabolite or circulating inhibitor in the uremic plasma, or biochemical changes produced by acute hemodialysis, may explain this finding. In cells with high cell Na + , the pump-mediated 42 K + transport is normalized at the expense of a raised cell Na + . The decreased muscle membrane potential in uremic subjects has been attributed to a decreased activity of Na + -K + pump. The authors discuss the role of hormonal abnormalities and circulating inhibitors, which may cause an acute inhibition of the pump and of other factors such as K + depletion, which may cause more chronic alterations. The implications of alteration of Na + and K + pump transport and raised cell Na + on other non-pump-mediated transport pathways are discussed. Raised cell Na + may be a marker for the adequacy of maintenance dialysis in patients with end-stage renal failure

  8. Izdelovalci glasbil na Slovenskem 1606–1918

    Directory of Open Access Journals (Sweden)

    Darja Koter

    2003-12-01

    Full Text Available Proučevanje zgodovine izdelovanja inštrumentov in posameznih izdelovalcev na Slovenskem nima dolge tradicije. Na ta del glasbene preteklosti je strokovno in drugo javnost prvi opozoril Josip Mantuani ob 60-letnici ljubljanske Glasbene matice leta 1932, ki je ob tej priložnosti v Narodnem domu v Ljubljani organizirala veliko razstavo Razvoj glasbe pri Slovencih, kjer so bili z izdelki predstavljeni tudi nekateri starejši in sodobni domači izdelovalci inštrumentov. Med najmanj razvitimi segmenti muzikologije na Slovenskem sta organologija glasbenih inštrumentov in zgodovina izdelovanja glasbil. Večje strokovne pozornosti so bile deležne predvsem orgle in orglarji. Orglarstvo in posamezne mojstre so od sedemdesetih let naprej proučevali Ladislav Šaban, Milko Bizjak in Edo Škulj, v zadnjem desetletju pa se stopnjuje zanimanje še za izdelovalce drugih inštrumentov, ki so v preteklih stoletjih delovali na ozemlju današnje Slovenije. Rezultati posameznih študij so objavljeni v različnih publikacijah, revijah, zbornikih in leksikonih, nekaj podatkov o izdelovalcih pa najdemo tudi v tuji literaturi. Da bi bilo poznavanje zgodovine izdelovanja glasbil in posameznih mojstrov bolj pregledno in dostopnejše, je nujno, da objavljene dosežke strnemo v obliki gesel z vsemi najbolj vitalnimi podatki, s čimer bodo imeli uporabniki boljši dostop do informacij. Pri oblikovanju gesel je bila upoštevana metodologija, ki se je uveljavila v nemški in angleški leksikografski literaturi. Imena izdelovalcev so zapisana v izvirni obliki, ponekod pa so dodane še različice priimkov in imen, ki jih najdemo v primarnih virih. Pri rojstnih podatkih so navedene letnice rojstva in smrti ter natančni datumi, kadar so znani. V primerih, kjer čas rojstva ni ugotovljen, so pomembne letnice delovanja posameznika. Primer: CAJHEN, (Zeichen, Martin (1855–1863. Pri poklicu je mogočih več navedb, npr. izdelovalec orgel, organist, trgovec z glasbili ... Kadar

  9. A metodologia de projecto na aprendizagem da biodiversidade e geodiversidade na praia da concha

    OpenAIRE

    Rosa, Marina Maria Filipe

    2012-01-01

    Dissertação de mestrado em Biologia e de Geologia, apresentada ao Departamento de Ciências da Terra e ao Departamento de Ciências da Vida Este trabalho consistiu na implementação e avaliação da metodologia de projeto no estudo da Biodiversidade e Geodiversidade na Praia da Concha, Portugal Central, dando ênfase ao trabalho prático, através de uma aula de campo e de aulas laboratoriais. O trabalho foi realizado numa escola da Marinha Grande, com 11 alunos do 10º ano de escolaridade. Sendo a...

  10. Velocity distribution and dimer formation in a Na/Na2 beam

    International Nuclear Information System (INIS)

    Bergmann, K.; Hefter, U.; Hering, P.

    1977-01-01

    Using the TOF via optical pumping method and the Doppler-shifted laser induced emission described previously, the authors have measured the parallel and perpendicular velocity distribution respectively for Na atoms and Na 2 molecules in a variety of individual quantum states. In addition they monitored the flux of molecules in specific states while changing the stagnation pressure. In all cases a significant dependence on the internal energy of the molecules was found. The goal of these experiments is to improve understanding of the beam dynamics and the dimer formation process. (Auth.)

  11. OGLAŠEVANJE NA SOCIALNEM OMREŽJU FACEBOOK, NA PRIMERU SPLETICNA.SI

    OpenAIRE

    Reisman, Nina

    2011-01-01

    Internet je od svojega razvoja dolgo časa obstajal kot prostor za enostransko komunikacijo. Isto se je dogajalo na televiziji, radiu in časopisih, kjer je javnost sprejemala informacije, ki jih je nekdo pripravil. Tradicionalni mediji so hitro doumeli, da takšna vrsta komunikacije ni naravna in ne predstavlja najboljšega ohranjanja gledalcev in poslušalcev. Začela se je uporabljati dvosmerna komunikacija. Trenutno v svetu najbolje poznan primer dvosmerne komunikacije je socialno omrežje F...

  12. Design and implementation of the NaI(Tl)/CsI(Na) detectors output signal generator

    International Nuclear Information System (INIS)

    Zhou Xu; Liu Congzhan; Zhao Jianling

    2014-01-01

    We designed and implemented a signal generator that can simulate the output of the NaI(Tl)/CsI(Na) detectors' pre-amplifier onboard the Hard X-ray Modulation Telescope (HXMT). Using the development of the FPGA (Field Programmable Gate Array) with VHDL language and adding a random constituent, we have finally produced the double exponential random pulse signal generator. The statistical distribution of the signal amplitude is programmable. The occurrence time intervals of the adjacent signals contain negative exponential distribution statistically. (authors)

  13. Design and implementation of the NaI(Tl)/CsI(Na) detectors output signal generator

    Science.gov (United States)

    Zhou, Xu; Liu, Cong-Zhan; Zhao, Jian-Ling; Zhang, Fei; Zhang, Yi-Fei; Li, Zheng-Wei; Zhang, Shuo; Li, Xu-Fang; Lu, Xue-Feng; Xu, Zhen-Ling; Lu, Fang-Jun

    2014-02-01

    We designed and implemented a signal generator that can simulate the output of the NaI(Tl)/CsI(Na) detectors' pre-amplifier onboard the Hard X-ray Modulation Telescope (HXMT). Using the development of the FPGA (Field Programmable Gate Array) with VHDL language and adding a random constituent, we have finally produced the double exponential random pulse signal generator. The statistical distribution of the signal amplitude is programmable. The occurrence time intervals of the adjacent signals contain negative exponential distribution statistically.

  14. Subnitride chemistry: A first-principles study of the NaBa3N, Na5Ba3N, and Na16Ba6N phases

    International Nuclear Information System (INIS)

    Oliva, Josep M.

    2005-01-01

    An ab initio study on the electronic structure of the subnitrides NaBa 3 N, Na 5 Ba 3 N, and Na 16 Ba 6 N is performed for the first time. The NaBa 3 N and Na 5 Ba 3 N phases consist of infinite 1 ∞ [NBa 6/2 ] strands composed of face-sharing NBa 6 octahedra surrounded by a 'sea' of sodium atoms. The Na 16 Ba 6 N phase consist of discrete [NBa 6 ] octahedra arranged in a body-cubic fashion, surrounded by a 'sea' of sodium atoms. Our calculations suggest that the title subnitrides are metals. Analysis of the electronic structure shows partial interaction of N(2s) with Ba(5p) electrons in the lower energy region for NaBa 3 N and Na 5 Ba 3 N. However, no dispersion is observed for the N(2s) and Ba(5p) bands in the cubic phase Na 16 Ba 6 N. The metallic band below the Fermi level shows a strong mixing of N(2p), Ba(6s), Ba(5d), Ba(6p), Na(3s) and Na(3p) orbitals. The metallic character in these nitrides stems from delocalized electrons corresponding to hybridized 5d l 6s m 6p n barium orbitals which interact with hybridized 3s n 3p m sodium orbitals. Analysis of the electron density and electronic structure in these nitrides shows two different regions: a metallic matrix corresponding to the sodium atoms and the regions around them and heteropolar bonding between nitrogen and barium within the infinite 1 ∞ [NBa 6/2 ] strands of the NaBa 3 N and Na 5 Ba 3 N phases, and within the isolated [NBa 6 ] octahedra of the Na 16 Ba 6 N phase. The nitrogen atoms inside the strands and octahedra are negatively charged, the anionic character of nitrogens being larger in the isolated octahedra of the cubic phase Na 16 Ba 6 N, due to the lack of electron delocalization along one direction as opposed to the other phases. The sodium and barium atoms appear to be slightly negatively and positively charged, the latter to a larger extent. From the computed Ba-N overlap populations as well as the analysis of the contour maps of differences between total density and superposition of

  15. NaI(Tl) response functions

    Energy Technology Data Exchange (ETDEWEB)

    Vega C, H. R.; Ortiz R, J. M. [Universidad Autonoma de Zacatecas, Unidad Academica de Estudios Nucleares, Cipres No. 10, Fracc. La Penuela, 98068 Zacatecas, Zac. (Mexico); Benites R, J. L. [Centro Estatal de Cancerologia de Nayarit, Calz. de la Cruz 118 Sur, Tepic, Nayarit (Mexico); De Leon M, H. A., E-mail: fermineutron@yahoo.com.mx [Instituto Tecnologico de Aguascalientes, Av. Adolfo Lopez Mateos 1801 Ote., 20155 Aguascalientes, Ags. (Mexico)

    2015-09-15

    The response functions of a NaI(Tl) detector have been estimated using Monte Carlo methods. Response functions were calculated for monoenergetic photon sources (0.05 to 3 MeV). Responses were calculated for point-like sources and for sources distributed in Portland cement cylinders. The responses were used to calculate the efficiency functions in term of photon energy. Commonly, sources used for calibration are point-like, and eventually sources to be measured have different features. In order to use the calibrated sources corrections due to solid angle, self-absorption and scattering, must be carried out. However, some of these corrections are not easy to perform. In this work, the calculated responses were used to estimate the detector efficiency of point-like sources, and sources distributed in Portland type cement. Samples of Portland paste were prepared and were exposed to photoneutrons produced by a 15 MV linac. Some of the elements in the cement were activated producing γ-emitting radionuclides that were measured with a NaI(Tl) gamma-ray spectrometer, that was calibrated with point-like sources. In order to determine the specific activity in the induced radioisotopes calculated efficiencies were used to make corrections due to the differences between the solid angle, photon absorption and photon scattering in the point-like calibration sources and the sources distributed in cement. During the interaction between photoneutrons and the cement samples three radioisotopes were induced: {sup 56}Mn, {sup 24}Na, and {sup 28}Al. (Author)

  16. Teratological studies of DTPA-CaNa3, DTPA-ZnNa3 and quinamic acid in mice

    International Nuclear Information System (INIS)

    Luo Meichu; Ruan Tianming; Tong Shungao

    1989-01-01

    DTPA-CaNa 3 , DTPA-ZnNa 3 and quinamic acid are effective chelating agents for removing actinide elements from the body. In this experiment, different doses of DTPA-CaNa 3 , DTPA-ZnNa 3 and quinamic acid were given to mice on gestation days 6-10. Eight groups of mice received 0.8 and 2.0 mM/kg of DTPA-CaNa 3 , 3.8, 7.6, and 11.4 mM/kg of DTPA-ZnNa 3 and 0.42, 2.1, and 4.2 mM/kg of quinamic acid. Hypetonic saline and isotonic saline were given to two control groups. DTPA-CaNa 3 and quinamidic acid were found to be much more toxic to fetus of mice than DTPA-ZnNa 3 . When the doses of DTPA-CaMa 3 and quinamidic acid were 20 times higher than the human dose, the number of resorbed fetus was increased and the number and weight of live fetus were reduced. The result of injection with 7.6 mM/kg (200 times of human dose)DTPA-ZnNa 3 and that of injection with isotonic saline are the same. Therefore, we suggest that the DTPA-CaNa 3 and quinamidic acid should not be given to pregnant woman, if chelation therapy is needed, while the much safer DTPA-ZnNa 3 could be used

  17. Results on leptonic probes from NA50

    CERN Document Server

    Alessandro, B; Arnaldi, R; Atayan, M; Baglin, C; Baldit, A; Bedjidian, Marc; Beolè, S; Boldea, V; Bordalo, P; Borenstein, S R; Borges, G; Bussière, A; Capelli, L; Castanier, C; Castor, J I; Chaurand, B; Cheynis, B; Chiavassa, E; Cicalò, C; Claudino, T; Comets, M P; Constantinescu, S; Cortese, P; Cruz, J; De Falco, A; De Marco, N; Dellacasa, G; Devaux, A; Dita, S; Drapier, O; Espagnon, B; Fargeix, J; Force, P; Gallio, M; Gavrilov, Yu K; Gerschel, C; Giubellino, P; Golubeva, M B; Gonin, M; Grigorian, A A; Grigorian, S; Grossiord, J Y; Guber, F F; Guichard, A; Gulkanian, H R; Hakobyan, R S; Haroutunian, R; Idzik, M; Jouan, D; Karavitcheva, T L; Kluberg, L; Kurepin, A B; Le Bornec, Y; Lourenço, C; Macciotta, P; MacCormick, M; Marzari-Chiesa, A; Masera, M; Masoni, A; Monteno, M; Musso, A; Petiau, P; Piccotti, A; Pizzi, J R; Prado da Silva, W L; Prino, F; Puddu, G; Quintans, C; Ramello, L; Ramos, S; Rato-Mendes, P; Riccati, L; Romana, A; Santos, H; Saturnini, P; Scalas, E; Scomparin, E; Serci, S; Shahoyan, R; Sigaudo, F; Sitta, M; Sonderegger, P; Tarrago, X; Topilskaya, N S; Usai, G L; Vercellin, Ermanno; Villatte, L; Willis, N; Wu, T

    2003-01-01

    The NA50 Collaboration has performed a new measurement of the J/ psi yield in Pb-Pb collisions at 158 GeV/nucleon in improved experimental conditions. Our preliminary analysis of the year 2000 data sample, while confirming the onset of anomalous suppression and the non saturation of the J/ psi /Drell-Yan cross-section ratio, shows that peripheral Pb-Pb interactions follow the normal nuclear absorption pattern, which has in turn been established more precisely thanks to high statistics p-A data. (11 refs).

  18. Disfonia na criança

    OpenAIRE

    Marta, Diana Simões

    2017-01-01

    Trabalho Final do Curso de Mestrado Integrado em Medicina, Faculdade de Medicina, Universidade de Lisboa, 2017 Disfonia é um termo clínico que se refere a todas as alterações e dificuldades na emissão vocal que impedem a produção normal da voz. É um sintoma frequente em idade pediátrica com consequências negativas em vários aspetos da vida da criança. Este artigo tem como objetivo resumir o conhecimento atual sobre a definição, epidemiologia, etiologia, características clínicas, abordag...

  19. Skate na cidade, imagens da cidade

    OpenAIRE

    Machado, Giancarlo Marques Carraro

    2014-01-01

    Apesar da existência de dezenas de pistas de skate na cidade de São Paulo – espaços considerados “próprios” para o skate -, a maioria dos skatistas da modalidade street skate confere maior importância à prática feita nas ruas, onde, para muitos, se “anda de skate de verdade”. A atração que elas exercem é a possibilidade de encontrar diferentes tipos de picos, ou seja, equipamentos urbanos (bancos, corrimãos, escadas, canteiros) obstáculos onde se realizam as manobras. Este artigo busca analis...

  20. The NA62 experiment at CERN

    International Nuclear Information System (INIS)

    Piccini, Mauro

    2016-01-01

    The rare decays K → πvv-bar are excellent processes to make tests of new physics at the highest scale complementary to LHC thanks to their theoretically cleanness. The NA62 experiment at CERN SPS aims to collect of the order of 100 events in two years of data taking for the decay K"+ → π"+vv-bar, keeping the background at the level of 10%. Part of the experimental apparatus has been commissioned during a technical run in 2012. The diverse and innovative experimental techniques will be explained and some preliminary results obtained during the 2014 pilot run will be reviewed

  1. Cerenkov counter for the experiment NA3

    CERN Multimedia

    1978-01-01

    The program of the NA3 experiment included the study of hadronic interactions with a large transverse momentum pT, thus the inclusion in the set-up of three gas threshold Cerenkov counters of large acceptance. The photo shows the downstream part of the second Cerenkov (located at the output of the magnet). The yellow membrane is a temporary protection for the optics (shown in photo 7810540X) to be taken away when fixing this part to the gas tank (entering the magnet and not shown). The photomultipliers all around are heavily shielded.

  2. Na(+),K (+)-ATPase as a docking station: protein-protein complexes of the Na(+),K (+)-ATPase.

    Science.gov (United States)

    Reinhard, Linda; Tidow, Henning; Clausen, Michael J; Nissen, Poul

    2013-01-01

    The Na(+),K(+)-ATPase, or sodium pump, is well known for its role in ion transport across the plasma membrane of animal cells. It carries out the transport of Na(+) ions out of the cell and of K(+) ions into the cell and thus maintains electrolyte and fluid balance. In addition to the fundamental ion-pumping function of the Na(+),K(+)-ATPase, recent work has suggested additional roles for Na(+),K(+)-ATPase in signal transduction and biomembrane structure. Several signaling pathways have been found to involve Na(+),K(+)-ATPase, which serves as a docking station for a fast-growing number of protein interaction partners. In this review, we focus on Na(+),K(+)-ATPase as a signal transducer, but also briefly discuss other Na(+),K(+)-ATPase protein-protein interactions, providing a comprehensive overview of the diverse signaling functions ascribed to this well-known enzyme.

  3. Effect of growth in lithium on ouabain binding, Na-K-ATPase and Na and K transport in hela cells.

    Science.gov (United States)

    Boardman, L J; Hume, S P; Lamb, J F; Polson, J

    1975-01-01

    1. HeLa cells were grown for 24 hr in growth medium in which part of the Na was replaced with Li. Ion contents, cell volumes and numbers, Na-K-ATPase and specific ouabain binding were measured. In some experiments the Na efflux and net Na transport was also measured. 2. Growth in Li caused a rise in the specific ouabain binding and membrane Na-K-ATPase of these cells. The Li concentrations in the cells necessary to produce this effect ranged up to 50 mM. 3. It is suggested that Li, like Na, acts on the genetic material of the cells to cause the production of more Na pumps within the membrane. PMID:124350

  4. Lipodystrophy syndrome associated with antiretroviral therapy in HIV patients: considerations for psychosocial aspects Síndrome de la lipodistrofia asociado con la terapia antiretroviral en pacientes con VIH: consideraciones para los aspectos psicosociales Sindrome da lipodistrofia associada com a terapia anti-retroviral em portadores do HIV: considerações para os aspectos psicossociais

    Directory of Open Access Journals (Sweden)

    Ana Paula Morais Fernandes

    2007-10-01

    son necesarios para entender mejor este complejo síndrome, proveyendo nueva información para ser utilizada en el cuidado de enfermería para pacientes con VIH que están afectados por este problema.Diversos efeitos colaterais têm sido associados à terapia anti-retroviral em portadores da infecção pelo HIV, dentre esses, a síndrome da lipodistrofia apresentando hiperlipidemia e alterações na forma do corpo, com hipertrofia adiposa central e lipoatrofia periférica, relatada pelos pacientes como um visível marcador para a identificação de portadores da infecção pelo HIV. Este estudo consiste em análise da produção científica sobre aspectos psicossociais em portadores da infecção pelo HIV que apresentam lipodistrofia associada à utilização da terapia anti-retroviral. Os resultados mostram que alterações corporais podem ser suficientemente perturbadoras para o bem-estar psicossocial, afetando a qualidade de vida e aumentando o estigma da doença, ocasionando perturbações nas relações sociais. Esta revisão possibilita uma análise preliminar dos aspectos psicossocias da lipodistrofia; entretanto, outros estudos são necessários para o melhor entendimento desta complexa síndrome, trazendo novas informações a serem utilizadas no cuidado de enfermagem a portadores da infecção pelo HIV afetados por este problema.

  5. Avaliação da importância da coloração de Perls na rotina de mielogramas de pacientes com anemia associada a uma ou mais citopenias em sangue periférico Evaluation of the importance of Perls stain in the routine testing of myelograms of patients with anemia associated with one or more peripheral blood cytopenias

    Directory of Open Access Journals (Sweden)

    Nydia S. Bacal

    2005-06-01

    Full Text Available As síndromes mielodisplásicas (SMD são um grupo heterogêneo de doenças malignas das células-tronco hematopoéticas, classificadas segundo a Organização Mundial da Saúde (OMS em: anemia refratária, anemia refratária com sideroblastos em anel, citopenia refratária com displasia de multilinhagens, anemia refratária com excesso de blastos, síndrome mielodisplásica inclassificável e sindrome mielodisplásica associada com anormalidade isolada do cromossomo 5q(del. Na anemia refratária com sideroblastos em anel observam-se hiperplasia e displasia eritróide com presença de 15% ou mais de sideroblastos em anel. Utilizamos neste estudo a coloração de Perls em esfregaços de medula óssea de pacientes com idade superior a 40 anos e que apresentavam uma ou mais citopenias no sangue periférico associada a anemia. Por tratar-se de técnica de manejo fácil e ágil sugerimos seu emprego em esfregaços de aspirado de medula óssea de pacientes que apresentem os achados laboratoriais acima, pois, dentre os casos analisados 18,7% apresentavam mais que 10 grânulos sideróticos circundando a terça parte ou mais do núcleo do precursor eritróide (sideroblasto em anel, sugerindo ao hematologista um possível diagnóstico de Síndrome Mielodisplásica com Sideroblastos em Anel (SMD-ARSA. Importante relatar que a grande maioria destes casos com aumento de sideroblastos em anel não foi encaminhada ao nosso serviço, com suspeita de SMD, e em somente um caso foi solicitada a realização da coloração de Perls.Myelodisplastic syndromes are a heterogeneous group of malignant haematopoietic stem cells. They are classified by the World Health Organization as refractory anemia, refractory anemia with ringed sideroblasts, refractory cytopenia with multilineage displasia, refractory anemia with excess of blast cells, unclassified myelodisplastic syndrome and myelodisplastic syndrome associated with a 5q chromosomal delection. Refractory anemia with

  6. The relation between aging, aortic NaF avidity and coronary artery NaF avidity: A NaF PET CT study

    DEFF Research Database (Denmark)

    Blomberg, Björn; Thomassen, Anders; Hildebrandt, Malene

    2013-01-01

    volunteers without traditional cardiovascular risk factors were prospectively assessed by Sodium 18-Fluoride (Na-18F) PET CT imaging. Global aortic uptake of Na-18F was determined by calculating the average aortic blood pool subtracted maximum standardized uptake value (cSUV) [maximum SUVaorta - mean...

  7. Minimizing Load Effects on NA4 Gear Vibration Diagnostic Parameter

    Science.gov (United States)

    Dempsey, Paula J.; Zakrajsek, James J.

    2001-01-01

    NA4 is a vibration diagnostic parameter, developed by researchers at NASA Glenn Research Center, for health monitoring of gears in helicopter transmissions. The NA4 reacts to the onset of gear pitting damage and continues to react to the damage as it spreads. This research also indicates NA4 reacts similarly to load variations. The sensitivity of NA4 to load changes will substantially affect its performance on a helicopter gearbox that experiences continuously changing load throughout its flight regimes. The parameter NA4 has been used to monitor gear fatigue tests at constant load. At constant load, NA4 effectively detects the onset of pitting damage and tracks damage severity. Previous research also shows that NA4 reacts to changes in load applied to the gears in the same way it reacts to the onset of pitting damage. The method used to calculate NA4 was modified to minimize these load effects. The modified NA4 parameter was applied to four sets of experimental data. Results indicate the modified NA4 is no longer sensitive to load changes, but remains sensitive to pitting damage.

  8. Advancement of technology towards developing Na-ion batteries

    Science.gov (United States)

    Jamesh, Mohammed Ibrahim; Prakash, A. S.

    2018-02-01

    The Na-ion-batteries are considered much attention for the next-generation power-sources due to the high abundance of Na resources that lower the cost and become the alternative for the state of the art Li-ion batteries in future. In this review, the recently reported potential cathode and anode candidates for Na-ion-batteries are identified in-light-of-their high-performance for the development of Na-ion-full-cells. Further, the recent-progress on the Na-ion full-cells including the strategies used to improve the high cycling-performance (stable even up-to 50000 cycles), operating voltage (even ≥ 3.7 V), capacity (>350 mAhg-1 even at 1000 mAg-1 (based-on-mass-of-the-anode)), and energy density (even up-to 400 Whkg-1) are reviewed. In addition, Na-ion-batteries with the electrodes containing reduced graphene oxide, and the recent developments on symmetric Na-ion-batteries are discussed. Further, this paper identifies the promising Na-ion-batteries including the strategies used to assemble full-cell using hard-carbon-anodes, Na3V2(PO4)3 cathodes, and other-electrode-materials. Then, comparison between aqueous and non-aqueous Na-ion-batteries in terms of voltage and energy density has been given. Later, various types of electrolytes used for Na-ion-batteries including aqueous, non-aqueous, ionic-liquids and solid-state electrolytes are discussed. Finally, commercial and technological-developments on Na-ion-batteries are provided. The scientific and engineering knowledge gained on Na-ion-batteries afford conceivable development for practical application in near future.

  9. Criptococose pulmonar: aspectos na tomografia computadorizada

    Directory of Open Access Journals (Sweden)

    Silva Ana Carina Gamboa da

    2003-01-01

    Full Text Available A criptococose pulmonar é uma doença causada pelo Criptococcus neoformans, um fungo unimórfico que possui distribuição mundial, existindo na mesma forma tanto no seu habitat natural quanto em animais e humanos. A doença possui apresentações clínica e patológica variáveis e pode manifestar-se tanto em pacientes com a imunidade normal como em imunocomprometidos, que representam a maioria dos casos. Neste trabalho são analisados os aspectos encontrados nas tomografias computadorizadas do tórax de 14 pacientes com criptococose pulmonar confirmada. Os achados mais freqüentes na tomografia do tórax foram as massas e os nódulos pulmonares. Outros aspectos observados foram as áreas de escavação, as consolidações, o espessamento do interstício peribroncovascular e o reticulado difuso. Massa pulmonar foi o achado isolado mais comum (64,2%, seguido dos nódulos isolados ou múltiplos (35,7%. Doença pulmonar difusa foi vista em apenas 14,2% dos casos. Os lobos superiores foram os mais comprometidos, sendo a doença mais comum nas regiões anteriores. A tomografia do tórax permitiu avaliar com precisão o grau de comprometimento do parênquima pulmonar.

  10. Vinhos, Turismo e Pluriatividade na Agricultura

    Directory of Open Access Journals (Sweden)

    Hernanda Tonini

    2013-06-01

    Full Text Available A gastronomia, além de ter importante relação com a economia, é uma forma expressiva da cultura dos indivíduos, desde o tipo de alimentos cultivados até a maneira de seu preparo e consumo. O presente artigo propõe-se a analisar a relação entre o enoturismo – centralizado na existência do vinho enquanto elemento gastronômico – e o fenômeno da pluriatividade na agricultura familiar, vista nos últimos anos como alternativa positiva para sua reprodução econômica e social. O fluxo turístico em regiões vitivinícolas gera novas oportunidades de trabalho e faz com que agricultores e suas famílias dividam a mão de obra agrícola, até então direcionada ao cultivo da uva e outros alimentos para subsistência, com atividades não agrícolas – como o artesanato, o acolhimento de visitantes em pousadas, a atuação em restaurantes, entre outras – como chance de subsistência. Este panorama transforma as realidades do mundo rural, alterando a relação do agricultor com a produção de alimentos e a forma como o mesmo os utiliza, além de reestruturar o ambiente sociocultural no seu entorno.  

  11. The NA60 experiment results and perspectives

    CERN Document Server

    Heuser, J M; Banicz, K; Borer, K; Buytaert, J; Castor, J I; Chaurand, B; Chenn, W; Cheynis, B; Cicalò, C; Colla, A; Cortese, R; David, A; De Falco, A; De Marco, N; Devaux, A; Drees, A; Ducroux, L; Enyo, H; Ferretti, A; Floris, M; Force, P; Grigorian, A A; Grossiord, J Y; Guettet, N; Guichard, A; Gulkanian, H R; Keil, M; Kluberg, L; Li, Z; Lourenço, C; Lozano-Bahilo, J; Manso, F; Masoni, A; Neves, A; Ohnishi, H; Oppedisano, C; Parracho, P; Puddu, G; Radermacher, E; Rosinsky, P; Scomparin, E; Seixas, J; Serci, S; Shahoyan, R; Sonderegger, P; Tieulent, R; Usai, G L; Vardanian, H; Veenhof, R; Wöhri, H K

    2003-01-01

    The NA60 experiment takes place at the SPS at CERN, to study the production of open charm and prompt dimuons in collisions induced by proton and heavy ion beams on nuclear targets. For this task, several novel detector systems were added to the dimuon spectrometer and zero-degree calorimeter, which were previously used in the NA50 experiment. The main upgrade is a new silicon pixel vertex spectrometer. It tracks the charged particles that are produced through the collisions in the target and allows us to match their trajectories and momenta with those of the muons that are measured behind the hadron absorber in the muon spectrometer. Besides improving considerably the dimuon mass resolution, the vertex telescope measures the offset of each muon track with respect to the interaction point. This allows us to select events where charm mesons were produced. We present in this article first results from dimuon data that were acquired in Summer 2002 with a 400 GeV proton beam. A silicon microstrip telescope was use...

  12. The NA62 GigaTracker

    CERN Document Server

    Perrin-Terrin, Mathieu

    2015-01-01

    The GigaTracker is an hybrid silicon pixel detector built for the NA62 experiment aiming at measuring the branching fraction of the ultra-rare kaon decay K + ! p + n ̄ n at the CERN SPS. The detector has to track particles in a beam with a flux reaching 1.3 MHz/mm 2 and provide single-hit timing with 200ps RMS resolution for a total material budget of less than 1.5 X 0 . The tracker comprises three 60.8mm 27mm stations installed in vacuum ( 10$^{-6}$ mbar) and cooled with liquid C 6 F 14 circulating through micro-channels etched inside few hundred of microns thick silicon plates. Each station is composed of a 200 m m thick silicon sensor readout by 2 x 5 cus- tom 100 m m thick ASIC, called TDCPix. Each chip contains 40 x 45 asynchronous pixels, each 300 m m x 300 m m and is instrumented with 100ps bin time-to-digital converters. In order to cope with the high rate, the TDCPix is equipped with four 3.2Gb/s serialisers sending out the data. We will describe the detector and the results from the 2014 NA62 ru...

  13. Status for 2018, CERN NA63

    CERN Document Server

    Nielsen, CF; Di Piazza, A; Wistisen, TN

    2018-01-01

    In the NA63 experiment of April 2018 the purpose was to look for the effect of the derivative term, the so-called Schott-term, in classical radiation reaction as described in \\cite{DiPiazza20171}. Data was taken for 20, 40 and 80 GeV electrons and positrons aligned to the $\\langle100\\rangle$ axis of a diamond crystal of thickness 1.5 mm, as well as for 40 and 80 GeV electrons on a 1.0 mm thick diamond aligned to the $\\langle100\\rangle$ axis. The data which was taken during the run shows encouraging results, but await a thorough analysis. For the 2017 data, the analysis is still ongoing, but expected to be finished within the coming few months. The results look very promising, but no final conclusion can be drawn at the present stage. For the 2016 results on quantum radiation reaction obtained by CERN NA63, the results have been published in Nature Communications \\cite{Wist17}.

  14. Direito do poeta na literatura de cordel

    Directory of Open Access Journals (Sweden)

    Sale Mário Gaudêncio

    Full Text Available Este artigo apresenta uma análise situacional dos direitos autorais na literatura de cordel, especialmente no que se refere à proteção moral e patrimonial que é dada aos poetas populares. Justifica-se o estudo em função de não haver profundas nem atuais discussões teóricas sobre a preservação moral e patrimonial em torno das obras de cordel. Utiliza-se como metodologia a pesquisa bibliográfica relacionada a um corpusque analisa os folhetos impressos por poetas da literatura de cordel. O estudo mostra como resultados o estabelecimento de um modelo alternativo de prazos para os direitos autorais na poesia popular, além da necessidade de ruptura técnica, política e cultural. Conclui informando sobre a importância de se construir um banco de dados nacional para que se tenha conhecimento pleno do quê e como se está produzindo a literatura de cordel, além de saber quem verdadeiramente está sendo beneficiado com tais produções.

  15. Plantas indicadoras de clomazone na fase vapor

    Directory of Open Access Journals (Sweden)

    Fábio Schreiber

    2013-10-01

    Full Text Available A volatilização representa um processo importante no deslocamento de agrotóxicos para o ambiente. As características físico-químicas da molécula do clomazone indicam que este possui potencial de volatilização. Em vista do exposto, para a realização deste estudo, foram conduzidos dois experimentos com o objetivo de avaliar a suscetibilidade das espécies: pepino, melão, milho, sorgo e arroz a diferentes formulações do herbicida clomazone na fase vapor. Para isso, foram utilizadas caixas de vidro hermeticamente fechadas, com a presença de diferentes formulações de clomazone e as espécies vegetais. As formulações utilizadas foram Gamit 360 CS®, Gamit 500 EC® e Gamit Star®. Com os resultados obtidos, foi possível concluir que, dentre as espécies avaliadas, independente da formulação utilizada, a de menor tolerância ao herbicida clomazone na fase vapor foi o sorgo, seguido do milho e do arroz.

  16. A biotecnologia na agropecuária

    Directory of Open Access Journals (Sweden)

    João Lúcio de Azevedo

    1986-11-01

    Full Text Available This review reports the use of biotechnology in agriculture and animal husbandry. The main techniques and the most important products both in experimental stage or in commercial use are reported. The work intends to give a global vision to the theme, chronologically and spacely, showing the main lines of research and what has been obtained in this area. The techniques and products that are related to genetics and breeding are emphasized. Revisão Bibliográfica do emprego da biotecnologia na agropecuária, mostrando um levantamento das técnicas mais promissoras e de seus principais produtos, tanto em fase experimental como em uso comercial. Pretende-se dar uma visão global do assunto, cronológica e espacialmente, não se prendendo à detalhes, mostrando, em Unhas gerais, o que foi feito e o que se faz, atualmente, em biotecnologia. As técnicas e produtos que influenciam a área de genética e melhoramento genético na agropecuária, são enfatizadas.

  17. Mercosul educativo na carreira de Enfermagem

    Directory of Open Access Journals (Sweden)

    Roseli Schmoeller

    2012-10-01

    Full Text Available O Mercosul, instituído com vistas à integração econômica, política, social e cultural entre os países membros, atualmente destaca-se pelas estratégias integrativas de âmbito educacional. Este artigo aborda os movimentos acerca da formação acadêmica dos cursos de Enfermagem e o trajeto histórico de integração educacional, apresentando o Sistema de Acreditação dos Cursos Universitários do Mercosul, o ARCU-SUL, além dos setores responsáveis por esse processo e as perspectivas para a Enfermagem nos países do Mercosul. Entendemos que para o desenvolvimento de profissionais críticos, reflexivos e com compromisso político-social, é fundamental investir na formação e na qualidade dos centros de ensino em Enfermagem.

  18. Mechanochemical transformations in Li(Na)AlH4-Li(Na)NH2 systems

    International Nuclear Information System (INIS)

    Dolotko, Oleksandr; Zhang Haiqiao; Ugurlu, Ozan; Wiench, Jerzy W.; Pruski, Marek; Scott Chumbley, L.; Pecharsky, Vitalij

    2007-01-01

    Mechanochemical transformations of tetrahydroaluminates and amides of lithium and sodium have been investigated using gas volumetric analysis, X-ray powder diffraction, solid-state nuclear magnetic resonance (NMR) and transmission electron microscopy. In a transformation of LiAlH 4 and LiNH 2 taken in an 1:1 molar ratio, the amount of released hydrogen (6.6 wt.% after 30 min ball milling) was higher than in any known one pot mechanochemical process involving a hydrogen-containing solid. A total of 4.3 wt.% of hydrogen is released by the NaAlH 4 -NaNH 2 system after 60 min ball milling; and 5.2 wt.% H 2 is released when LiAlH 4 and NaNH 2 or NaAlH 4 and LiNH 2 are ball milled for 90 min and 120 min, respectively. All transformations proceed at room temperature. The mechanism of the overall transformation MAlH 4 (s) + MNH 2 (s) → 2MH(s) + AlN(s) + 2H 2 (g) was identified based on detailed spectroscopic analysis of the intermediate (M 3 AlH 6 ) and final products of the ball milling process

  19. Aspectos valorizados por porfissionais de enfermagem na higiene pessoal e na higiene corporal do paciente

    Directory of Open Access Journals (Sweden)

    Elóide André Oliveira

    2003-10-01

    Full Text Available Survey descritivo, com o qual se objetivou identificar que aspectos da higiene corporal são valorizados pelos componentes da equipe de enfermagem, na higiene corporal pessoal e na higiene corporal do paciente. A pesquisa foi desenvolvida em oito instituições públicas de saúde e a amostra foi composta por 126 profissionais de enfermagem, correspondendo a 12,8% do total de 986 componentes das equipes de enfermagem destas instituições. Na higiene corporal pessoal, chamou a atenção o fato de que os cuidados com as unhas e com os cabelos tenham suplantado, no número de citações dos profissionais de enfermagem, aspectos básicos como o cuidado com as mãos. Na higiene corporal do paciente, o banho foi o aspecto considerado mais importante pelas três categorias profissionais; a higiene oral, pelas(os enfermeiras(os e auxiliares de enfermagem; e as unhas, pelas(os enfermeiras(os e técnicas(os de enfermagem.

  20. Excess Enthalpies of Mixing of Binary Mixtures of NaCl, KCl, NaBr ...

    African Journals Online (AJOL)

    NJD

    2004-07-01

    Jul 1, 2004 ... NaBr and KBr in Mixed Ternary Solvent Systems at 298.15 K. Bal Raj Deshwala* ... industrial waters and their thermodynamic properties are of practical interest for .... The enthalpy of mixing (∆Hm) is the difference between the excess enthalpy of the ..... tural (categorized by softness, open- ness, and ...

  1. Síndrome de lennox-gastaut com início na vida adulta? a respeito de um caso

    Directory of Open Access Journals (Sweden)

    P. C. Trevisol-Bittencourt

    1990-12-01

    Full Text Available Apesar de ter sido relatada anteriormente, a sindrome de Lennox-Gastaut (SLG só foi definitivamente aceita como entidade distinta em 1966. Desde então, o epônimo tem sido utilizado para designar encefalopatia severa da infância, caracterizada fundamentalmente por crises epilépticas refratárias de diversos tipos associadas com alterações eletrográficas típicas. Entretanto, vários autores consideram que o rótulo de SLG está abrigando quadros nosológicos distintos, que deveriam ser separados e individualizados. Ilustrando esta situação, o caso de um paciente que iniciou quadro de «SLG-like» aos 20 anos de idade é relatado. Adicionando mais confusão, alguns casos semelhantes têm sido descritos nos últimos anos sob variada nomenclatura. Desde que um dos principais critérios para o diagnóstico da SLG é a idade dependência, como deverão então ser chamados tais quadros? Revisão dos critérios empregados para o diagnóstico da SLG se faz necessária.

  2. Efeito do plasma de oxigênio na dentina previamente exposta ao NaOCl

    Directory of Open Access Journals (Sweden)

    Maíra do PRADO

    Full Text Available Resumo Introdução O tratamento de plasma é uma tecnologia eficaz que pode manter as propriedades internas dos materiais inalteradas após o tratamento, modificando apenas a superfície. Objetivo Avaliar o efeito do plasma de oxigênio na dentina previamente exposta ao NaOCl 6%. Material e método Foram utilizados 60 incisivos bovinos. A coroa foi removida, a raiz foi dividida e as faces planificadas, totalizando 120 segmentos referentes ao terço cervical. As amostras foram divididas em dois grupos: controle (imersa em NaOCl 6%, lavada com água destilada, seca, imersa em EDTA 17%, lavada e seca e plasma de oxigênio (após tratamento descrito no grupo controle, plasma de oxigênio foi aplicado por 30 s. As amostras foram avaliadas qualitativamente em relação à topografia por microscopia eletrônica de varredura, utilizando-se microfotografias com ampliação de 1.000×. O goniômetro Ramé-hart foi utilizado para a mensuração do ângulo de contato entre as superfícies e as seguintes soluções foram utilizadas: água, etilenoglicol e di-iodometano. Em seguida, a energia de superfície, representada pelas componentes polar e dispersiva, foi calculada. Avaliou-se também o escoamento dos cimentos Pulp Canal Sealer EWT (PCS e Real Sal SE (RS na superfície dentinária. Os dados foram analisados estatisticamente utilizando os testes Kruskal-Wallis e Mann-Whitney U (p<0,05. Resultado O tratamento com plasma levou à formação de uma camada semelhante à smear layer na superfície dentinária. Este tratamento levou a um aumento da energia de superfície e da componente polar, favorecendo a hidrofilicidade da superfície. Entretanto, desfavoreceu o escoamento do cimento PCS e não influenciou no escoamento do cimento RS. Conclusão O plasma de oxigênio ocasionou mudanças topográficas na superfície dentinária, favorecendo a hidrofilicidade desta. Contudo, não favoreceu o escoamento dos cimentos endodônticos na dentina.

  3. Stimulation of Na+/K+ ATPase activity and Na+ coupled glucose transport by β-catenin

    International Nuclear Information System (INIS)

    Sopjani, Mentor; Alesutan, Ioana; Wilmes, Jan; Dermaku-Sopjani, Miribane; Lam, Rebecca S.; Koutsouki, Evgenia; Jakupi, Muharrem; Foeller, Michael; Lang, Florian

    2010-01-01

    Research highlights: → The oncogenic transcription factor β-catenin stimulates the Na + /K + -ATPase. → β-Catenin stimulates SGLT1 dependent Na + , glucose cotransport. → The effects are independent of transcription. → β-Catenin sensitive transport may contribute to properties of proliferating cells. -- Abstract: β-Catenin is a multifunctional protein stimulating as oncogenic transcription factor several genes important for cell proliferation. β-Catenin-regulated genes include the serum- and glucocorticoid-inducible kinase SGK1, which is known to stimulate a variety of transport systems. The present study explored the possibility that β-catenin influences membrane transport. To this end, β-catenin was expressed in Xenopus oocytes with or without SGLT1 and electrogenic transport determined by dual electrode voltage clamp. As a result, expression of β-catenin significantly enhanced the ouabain-sensitive current of the endogeneous Na + /K + -ATPase. Inhibition of vesicle trafficking by brefeldin A revealed that the stimulatory effect of β-catenin on the endogenous Na + /K + -ATPase was not due to enhanced stability of the pump protein in the cell membrane. Expression of β-catenin further enhanced glucose-induced current (Ig) in SGLT1-expressing oocytes. In the absence of SGLT1 Ig was negligible irrespective of β-catenin expression. The stimulating effect of β-catenin on both Na + /K + ATPase and SGLT1 activity was observed even in the presence of actinomycin D, an inhibitor of transcription. The experiments disclose a completely novel function of β-catenin, i.e. the regulation of transport.

  4. RAZVOJ APLIKACIJE PRETOČNEGA VIDEA NA MOBILNEM TELEFONU

    OpenAIRE

    Horvat, Jernej

    2012-01-01

    Diplomsko delo obravnava prenos video signala iz mobilnega telefona na TV. Prenos poteka preko Wi-Fi omrežja. Na mobilnem telefonu je nameščena ustrezna Android aplikacija, ki omogoča direkten prenos video signala in nalaganje na TV sprejemnik. Pomemben dejavnik, ki prispeva, da je ta proces mogoč, je sistem IMS (IP multimedijski podsistem), ki predstavlja omrežja naslednje generacije.

  5. Razvoj suvremenog menadžmenta trgovine na malo

    OpenAIRE

    Segetlija, Zdenko

    2009-01-01

    Razvoj koncentracije u trgovini na malo doveo je do daljnjih promjena u njezinoj strukturi te, u skladu s tim, i do promjena u upravljanju gospodarskim subjektima u trgovini na malo. S tim u svezi mijenja se i dosadašnja paradigma marketinga trgovine na malo, budući da sve važnijim postaje oblikovanje asortimana temeljem programa category managementa i drugih oblika vertikalnoga marketinga. S druge pak strane, osim poznavanja zakonitosti razvoja novih oblika poslovnih jedinica, no...

  6. STABILIZACIJA ROBOTA NA ŽOGI IN KALMANOV FILTER

    OpenAIRE

    Turk, Janez

    2016-01-01

    Stabilizacija robota na žogi je dvodimenzionalen problem inverznega nihala (Segway). V magistrskem delu je opisana izdelava strojnega dela robota (konstrukcije in vezja), načrtovanje vseh uporabljenih algoritmov ter potek programa v digitalnem signalnem procesorju. Glavni problem, ki smo se mu najbolj posvetili, je slab podatek o nagibu, ki ga pridobimo z zlivanjem senzorskih podatkov giroskopa in pospeškometra. Za izboljšanje delovanja je še veliko rezerve pri načrtovanju regulatorjev. Poleg...

  7. Transcriptional regulators of Na, K-ATPase subunits

    OpenAIRE

    Zhiqin eLi; Sigrid A Langhans

    2015-01-01

    The Na,K-ATPase classically serves as an ion pump creating an electrochemical gradient across the plasma membrane that is essential for transepithelial transport, nutrient uptake and membrane potential. In addition, Na,K-ATPase also functions as a receptor, a signal transducer and a cell adhesion molecule. With such diverse roles, it is understandable that the Na,K-ATPase subunits, the catalytic alpha-subunit, the beta-subunit and the FXYD proteins, are controlled extensively during developme...

  8. K+ congeners that do not compromise Na+ activation of the Na+,K+-ATPase

    DEFF Research Database (Denmark)

    Mahmmoud, Yasser A; Kopec, Wojciech; Khandelia, Himanshu

    2015-01-01

    The Na(+),K(+)-ATPase is essential for ionic homeostasis in animal cells. The dephosphoenzyme contains Na(+) selective inward facing sites, whereas the phosphoenzyme contains K(+) selective outward facing sites. Under normal physiological conditions, K(+) inhibits cytoplasmic Na(+) activation...

  9. RAHNER NA BERLINDA PÓS-CONCILIAR

    Directory of Open Access Journals (Sweden)

    Luciano Campos Lavall

    2004-01-01

    Full Text Available O artigo analisa algumas críticas negativas feitas ao pensamento teológico de Karl Rahner, após sua morte, que tentam desqualificar a sua importância para a ortodoxia católica e o seu distanciamento dos fundamentos do Concílio Vaticano II. Na discussão, enfocada sobretudo no ponto de vista da eclesiologia rahneriana, retoma importante entrevista do mesmo, no ano de sua morte, na qual aparece a sua preocupação com as chances futuras da Igreja, sobretudo na Europa Ocidental, a partir da qual abordam-se as relações entre Cristianismo e Igreja. As estratégias para a organização pastoral do mundo católico são a tônica desta reflexão. Para justificar suas posturas, o artigo termina com uma avaliação global de todo o conjunto teológico de Karl Rahner, redescobrindo nele os pilares mais fundamentais que justificam sua ortodoxia a serviço da fé cristã e católica, mas também a serviço da tomada de consciência de uma fé vivenciada e comprometida por parte da humanidade marcadamente secularizada. ABSTRACT: The article analyses negative criticisms against Rahner’s theological views after his death with the intention of discrediting him and his role in Catholic orthodoxy by distancing him from the fundamentals of Vatican Council II. In the discussion, primarily focused on Rahner’s ecclesiology, the article retakes a significant interview made the same year of Rahner’s death. In this interview his concern for the Church’s future chances, especially regarding Eastern Europe, embarking on relations between Christianity and Church. The strategies for world-wide organization of Catholic ministry predominate this reflection. Justifying its postures, the article concludes with a global evaluation of Rahner’s theology, rediscovering the fundamental pillars which justify his orthodoxy at the service of the Christian and Catholic faith, but also at the service of a conscientious living of a committed faith on behalf of a notably

  10. Secretory NaCl and volume flow in renal tubules.

    Science.gov (United States)

    Beyenbach, K W

    1986-05-01

    This review attempts to give a retrospective survey of the available evidence concerning the secretion of NaCl and fluid in renal tubules of the vertebrate kidney. In the absence of glomerular filtration, epithelial secretory mechanisms, which to this date have not been elucidated, are responsible for the renal excretion of NaCl and water in aglomerular fish. However, proximal tubules isolated from glomerular fish kidneys of the flounder, killifish, and the shark also have the capacity to secrete NaCl and fluid. In shark proximal tubules, fluid secretion appears to be driven via secondary active transport of Cl. In another marine vertebrate, the sea snake, secretion of Na (presumably NaCl) and fluid is observed in freshwater-adapted and water-loaded animals. Proximal tubules of mammals can be made to secrete NaCl in vitro together with secretion of aryl acids. An epithelial cell line derived from dog kidney exhibits secondary active secretion of Cl when stimulated with catecholamines. Tubular secretion of NaCl and fluid may serve a variety of renal functions, all of which are considered here. The occurrence of NaCl and fluid secretion in glomerular proximal tubules of teleosts, elasmobranchs, and reptiles and in mammalian renal tissue cultures suggests that the genetic potential for NaCl secretion is present in every vertebrate kidney.

  11. Dejavniki psihološkega nasilja na delovnem mestu

    OpenAIRE

    Ilc, Teja

    2011-01-01

    Raziskave na področju delovnih razmer kažejo, da je danes pereč problem ravno psihološko nasilje na delovnem mestu. Posebna oblika psihološkega nasilja na delovnem mestu je mobing, s katerim se v praksi srečujemo vsak dan, vendar se ga pogosto ne zavedamo. Namen magistrske naloge je pojasniti pojem in pomen mobinga v delovnih organizacijah, poiskati možne vzroke in posledice, ki vplivajo na ta pojav, ter predlagati rešitve. Poznavanje mehanizmov, ki povzročajo mobing, njegovih vzrokov in...

  12. Angular distributions of photoelectrons from free Na clusters

    International Nuclear Information System (INIS)

    Wopperer, P.; Dinh, P. M.; Faber, B.; Reinhard, P.-G.; Suraud, E.

    2010-01-01

    We explore, from a theoretical perspective, photoelectron angular distributions (PADs) of the Na clusters Na 8 , Na 10 , Na 12 , Na 18 , Na 3 + , Na 11 + , Na 13 + , and Na 19 + . The basis of the description is the time-dependent local-density approximation (TDLDA), augmented by a self-interaction correction (SIC) to describe ionization properties correctly. The scheme is solved on a numerical grid in coordinate space with absorbing bounds. We assume for each cluster system an isotropic ensemble of free clusters and develop for the case of one-photon emission analytical formulas for computing the orientation-averaged PAD on the basis of a few TDLDA-SIC calculations for properly chosen reference orientations. It turns out that all the information in the averaged PAD is contained in one anisotropy parameter. We find that this parameter varies very little with system size, but as a whole is crucially influenced by the detailed ionic structure. We also make comparisons with direct orientation averaging and consider one example reaching outside the perturbative regime.

  13. Transcriptional regulators of Na, K-ATPase subunits

    Directory of Open Access Journals (Sweden)

    Zhiqin eLi

    2015-10-01

    Full Text Available The Na,K-ATPase classically serves as an ion pump creating an electrochemical gradient across the plasma membrane that is essential for transepithelial transport, nutrient uptake and membrane potential. In addition, Na,K-ATPase also functions as a receptor, a signal transducer and a cell adhesion molecule. With such diverse roles, it is understandable that the Na,K-ATPase subunits, the catalytic alpha-subunit, the beta-subunit and the FXYD proteins, are controlled extensively during development and to accommodate physiological needs. The spatial and temporal expression of Na,K-ATPase is partially regulated at the transcriptional level. Numerous transcription factors, hormones, growth factors, lipids and extracellular stimuli modulate the transcription of the Na,K-ATPase subunits. Moreover, epigenetic mechanisms also contribute to the regulation of Na,K-ATPase expression. With the ever growing knowledge about diseases associated with the malfunction of Na,K-ATPase, this review aims at summarizing the best-characterized transcription regulators that modulate Na,K-ATPase subunit levels. As abnormal expression of Na,K-ATPase subunits have been observed in many carcinoma, we will also discuss transcription factors that are associated with epithelial-to-mesenchymal transition, a crucial step in the progression of many tumors to malignant disease.

  14. O grotesco na imagem publicitária

    OpenAIRE

    Silva, Maria João Barros

    2013-01-01

    O significado da palavra grotesco teve um começo puramente artístico numa descoberta, de imagens de figuras humanas deformadas e alteradas. No entanto, este foi evoluindo e adotando novos significados mais amplos e concretos na atualidade. É possível encontrar vários exemplos do grotesco em várias plataformas, como no cinema, na televisão e na literatura. Neste sentido, para se poder proceder ao estudo desta temática é fundamental a conquista do conhecimento sobre o estatuto do grotesco na pu...

  15. VPLIV ULCEROZNEGA KOLITISA NA KAKOVOST ŽIVLJENJA

    OpenAIRE

    Dugi, Maja

    2015-01-01

    Pri vsaki bolezni je zelo pomembna kakovost življenja pacientov. Ulcerozni kolitis je kronična bolezen, ki je znana po obdobjih mirovanja in izbruhov, kar definitivno vpliva na posameznika, ki se s tem spopada. Sooča se z raznimi omejitvami, ki vplivajo na njegov vsakdan. Rezultati raziskave so pokazali, da je kakovost življenja bolnikov z ulceroznim kolitisom izrazito okrnjena. Ne le, da se spopadajo z bolečino, ampak tudi s psihičnimi in socialnimi posledicami, ki vplivajo na fizične aktivn...

  16. ZAZNAVA IN VPLIV BARV NA PRIMERU TISKANIH OGLASOV

    OpenAIRE

    Spes, Katja

    2015-01-01

    V diplomski nalogi smo s pomočjo literature opisali simboliko osnovnih barv, vpliv, ki ga imajo na ljudi, ter njihov pomen v oglasnih sporočilih. Omejili smo se na tiskane oglase (plakate, časopise, revije, neposredno pošto in embalažo) in opisali njihove prednosti in slabosti. Z anketnim vprašalnikom smo ugotavljali, na katere barve smo najbolj pozorni in katerim lastnostim se posamezne barve bolj približajo. Osredotočili smo se na sedem barv

  17. Na/K Pump and Beyond: Na/K-ATPase as a Modulator of Apoptosis and Autophagy.

    Science.gov (United States)

    Felippe Gonçalves-de-Albuquerque, Cassiano; Ribeiro Silva, Adriana; Ignácio da Silva, Camila; Caire Castro-Faria-Neto, Hugo; Burth, Patrícia

    2017-04-21

    Lung cancer is a leading cause of global cancer deaths. Na/K-ATPase has been studied as a target for cancer treatment. Cardiotonic steroids (CS) trigger intracellular signalling upon binding to Na/K-ATPase. Normal lung and tumour cells frequently express different pump isoforms. Thus, Na/K-ATPase is a powerful target for lung cancer treatment. Drugs targeting Na/K-ATPase may induce apoptosis and autophagy in transformed cells. We argue that Na/K-ATPase has a role as a potential target in chemotherapy in lung cancer treatment. We discuss the effects of Na/K-ATPase ligands and molecular pathways inducing deleterious effects on lung cancer cells, especially those leading to apoptosis and autophagy.

  18. Scintillation efficiency measurement of Na recoils in NaI(Tl) below the DAMA/LIBRA energy threshold

    Energy Technology Data Exchange (ETDEWEB)

    Xu, Jingke; Shields, Emily; Calaprice, Frank; Westerdale, Shawn; Froborg, Francis; Suerfu, Burkhant; Alexander, Thomas; Aprahamian, Ani; Back, Henning O.; Casarella, Clark; Fang, Xiao; Gupta, Yogesh K.; Ianni, Aldo; Lamere, Edward; Lippincott, W. Hugh; Liu, Qian; Lyons, Stephanie; Siegl, Kevin; Smith, Mallory; Tan, Wanpeng; Kolk, Bryant Vande

    2015-07-01

    The dark matter interpretation of the DAMA modulation signal depends on the NaI(Tl) scintillation efficiency of nuclear recoils. Previous measurements for Na recoils have large discrepancies, especially in the DAMA/LIBRA modulation energy region. We report a quenching effect measurement of Na recoils in NaI(Tl) from 3 to 52 keVnr, covering the whole DAMA/LIBRA energy region for dark matter-Na scattering interpretations. By using a low-energy, pulsed neutron beam, a double time-of-flight technique, and pulse-shape discrimination methods, we obtained the most accurate measurement of this kind for NaI(Tl) to date. The results differ significantly from the DAMA reported values at low energies but fall between the other previous measurements. We present the implications of the new quenching results for the dark matter interpretation of the DAMA modulation signal.

  19. Na/K Pump and Beyond: Na/K-ATPase as a Modulator of Apoptosis and Autophagy

    Directory of Open Access Journals (Sweden)

    Cassiano Felippe Gonçalves-de-Albuquerque

    2017-04-01

    Full Text Available Lung cancer is a leading cause of global cancer deaths. Na/K-ATPase has been studied as a target for cancer treatment. Cardiotonic steroids (CS trigger intracellular signalling upon binding to Na/K-ATPase. Normal lung and tumour cells frequently express different pump isoforms. Thus, Na/K-ATPase is a powerful target for lung cancer treatment. Drugs targeting Na/K-ATPase may induce apoptosis and autophagy in transformed cells. We argue that Na/K-ATPase has a role as a potential target in chemotherapy in lung cancer treatment. We discuss the effects of Na/K-ATPase ligands and molecular pathways inducing deleterious effects on lung cancer cells, especially those leading to apoptosis and autophagy.

  20. A interdisciplinaridade na violência sexual

    OpenAIRE

    Azambuja,Maria Regina Fay de

    2013-01-01

    O artigo aborda a inquirição da vítima de violência sexual como afronta aos direitos humanos da criança, na medida em que busca a obtenção da prova em detrimento da proteção da vítima. Aponta a ação interdisciplinar como indispensável ao trabalho envolvendo violência sexual praticada contra a criança, dando ênfase à perícia realizada por profissionais de diversas áreas (Serviço Social, Psicologia, Pedagogia, Pediatra) como instrumento capaz de produzir a prova e de garantir a dignidade e o re...

  1. Symbiodinium isolation by NaOH treatment.

    Science.gov (United States)

    Zamoum, Thamilla; Furla, Paola

    2012-11-15

    The presence of photosynthetic zooxanthellae (dinoflagellates) in the tissue of many cnidarians is the main reason for their ecological success (i.e. coral reefs). It could also be the main cause of their demise, as the worldwide bleaching of reef-building coral is nothing less than the breakdown of this symbiotic association. The stability of this relationship is the principal marker for the biomonitoring of cnidarian health. We have therefore developed a new, simple method to isolate zooxanthellae in a few steps using NaOH solution. The protocol was validated in three symbiotic cnidarian species: a sea anemone, a gorgonian and a coral. Our method allows the isolation of intact and viable zooxanthellae with better yields than classic methods, especially for species with a calcareous skeleton. Moreover, the isolated zooxanthellae were free of host nucleic contaminants, facilitating subsequent specific molecular analyses.

  2. Pion and kaon freezeout in NA44

    International Nuclear Information System (INIS)

    1994-01-01

    The NA44 spectrometer is optimized for the study of single and two-particle particle spectra near mid-rapidity for transverse momenta below ∼ 1 GeV/c. A large fraction of all pairs in the spectrometer's acceptance are at low relative momenta, resulting in small statistical uncertainties on the extracted size parameters. In addition, the spectrometer's clean particle identification allows the authors to measure correlation functions for pions, kaons, and protons. This contribution will concentrate on the source size parameters determined from pion and kaon correlation functions. These size parameters will be compared to calculations from the RQMD event generator and also interpreted in the context of a hydrodynamic model. Finally, the measured single particle spectra will be examined from the viewpoint of hydrodynamics

  3. Redes sociais na internet: Sociabilidades emergentes

    OpenAIRE

    Amaral, Inês

    2016-01-01

    Na actual era da cultura digital é imperativo identificar e compreender os tipos de sociabilidade que emergem das novas práticas e relações que ocorrem no ciberespaço, para que seja possível teorizar sobre realidades sociais que são desenhadas em torno da apropriação do conteúdo e materializadas em plataformas que se assumem como o termómetro de uma sociedade sem determinismo geográfico. A sociabilização em contexto digital reporta-se ao princípio de que um mundo de informação (conteúdos, ...

  4. O operar de um coletivo na WEB

    Directory of Open Access Journals (Sweden)

    Karen Eidelwein

    Full Text Available Analisamos o operar de um grupo de discussão na WEB buscando identificar seu agenciamento enquanto coletivo autoprodutivo. Estabelecemos sete indicadores de operação e cinco categorias temáticas. A visualização de cada um dos indicadores de operação em cada uma das categorias temáticas possibilitou compreender o operar do grupo como decorrente das próprias relações que foram sendo estabelecidas, em um processo autoprodutivo, de causalidade recursiva. Foi possível argumentar que o grupo apresentou indícios de um modo de instituir-se capaz de apontar para outras formas de relação em torno da construção de objetos coletivos teóricos voltados para a ação fora do espaço digital.

  5. Bullying: ato esburacado na angústia

    Directory of Open Access Journals (Sweden)

    Maria de Lourdes Soares Ornellas

    2012-04-01

    Full Text Available A noção de afeto está no campo do (desprazer, resultante de uma experiência afetiva de satisfação ou insatisfação, e que se manifesta nas necessidades do sujeito. Pode-se dizer que o afeto envolve a ambivalência de sentimentos, do mais agradável ao mais insuportável, e desempenha um papel estruturante para que o sujeito reencontre sua estrutura psíquica, exercendo uma ação mediadora e decisiva sobre a constituição do sujeito do desejo, orientando o seu projeto de vida, sua profissão, sua opção sexual, etc. Essa ambivalência de afetos deve ser exercitada na educação familiar e escolar, na fala e na escuta que o afeto (desprazeroso tem relevância e parece ser silenciado. O desprazer pode ser escandido pelos sintomas medo, depressão, irritabilidade, ansiedade, humilhação. Assim posto o bullying é também conhecido como a síndrome da humilhação. O objetivo da humilhação é a tentativa de destruição do sujeito; a perda da identificação revela um fantasma, na medida em que própria vítima se sente culpada por sofrer ou por estar sofrendo um ato esburacado porque uma das peças não é encontrada e, em lugar do encaixe, o que se mostra é um buraco, o que provoca a angústia entre quem perde e aquele que ganha. ABSTRACT: The notion of affect is thus in the field of (dis pleasure, resulting from an affective experience of satisfaction or dissatisfaction, and that manifests itself on the needs of the subject. You could say that the affection involves the ambivalence of feelings, the more enjoyable the more unbearable, and plays a structural role for the subject to rediscover his psychic structure, exerting a mediator and decisive action on the constitution of the subject of desire, directing the its design life, your profession, your sexual orientation, etc.. This ambivalence of feelings should be exercised in family education and school, talking and listening that affect (dis pleasure is relevant and appears to be

  6. The NA49 large acceptance hadron detector

    International Nuclear Information System (INIS)

    Afanasiev, S.; Alber, T.; Appelshaeuser, H.; Baechler, J.; Barna, D.; Barnby, L.S.; Bartke, J.; Barton, R.A.; Betev, L.; Bialkowska, H.; Bieser, F.; Billmeier, A.; Blyth, C.O.; Bock, R.; Bormann, C.; Bracinik, J.; Brady, F.P.; Brockmann, R.; Brun, R.; Buncic, P.; Caines, H.L.; Cebra, D.; Cooper, G.E.; Cramer, J.G.; Csato, P.; Cyprian, M.; Dunn, J.; Eckardt, V.; Eckhardt, F.; Empl, T.; Eschke, J.; Ferguson, M.I.; Fessler, H.; Fischer, H.G.; Flierl, D.; Fodor, Z.; Frankenfeld, U.; Foka, P.; Freund, P.; Friese, V.; Ftacnik, J.; Fuchs, M.; Gabler, F.; Gal, J.; Ganz, R.; Gazdzicki, M.; Gladysz, E.; Grebieszkow, J.; Guenther, J.; Harris, J.W.; Hegyi, S.; Henkel, T.; Hill, L.A.; Hlinka, V.; Huang, I.; Huemmler, H.; Igo, G.; Irmscher, D.; Ivanov, M.; Janik, R.; Jacobs, P.; Jones, P.G.; Kadija, K.; Kolesnikov, V.I.; Kowalski, M.; Lasiuk, B.; Levai, P.; Liebicher, K.; Lynen, U.; Malakhov, A.I.; Margetis, S.; Markert, C.; Marks, C.; Mayes, B.; Melkumov, G.L.; Mock, A.; Molnar, J.; Nelson, J.M.; Oldenburg, M.; Odyniec, G.; Palla, G.; Panagiotou, A.D.; Pestov, Y.; Petridis, A.; Pikna, M.; Pimpl, W.; Pinsky, L.; Piper, A.; Porter, R.J.; Poskanzer, A.M.; Poziombka, S.; Prindle, D.J.; Puehlhofer, F.; Rauch, W.; Reid, J.G.; Renfordt, R.; Retyk, W.; Ritter, H.G.; Roehrich, D.; Roland, C.; Roland, G.; Rudolph, H.; Rybicki, A.; Sammer, T.; Sandoval, A.; Sann, H.; Schaefer, E.; Schmidt, R.; Schmischke, D.; Schmitz, N.; Schoenfelder, S.; Semenov, A.Yu.; Seyboth, J.; Seyboth, P.; Seyerlein, J.; Sikler, F.; Sitar, B.; Skrzypczak, E.; Squier, G.T.A.; Stelzer, H.; Stock, R.; Strmen, P.; Stroebele, H.; Struck, C.; Susa, T.; Szarka, I.; Szentpetery, I.; Szymanski, P.; Sziklai, J.; Toy, M.; Trainor, T.A.; Trentalange, S.; Ullrich, T.; Vassiliou, M.; Veres, G.; Vesztergombi, G.; Vranic, D.; Wang, F.Q.; Weerasundara, D.D.; Wenig, S.; Whitten, C.; Wieman, H.; Wienold, T.; Wood, L.; Yates, T.A.; Zimanyi, J.; Zhu, X.-Z.; Zybert, R.

    1999-01-01

    The NA49 detector is a wide acceptance spectrometer for the study of hadron production in p+p, p+A, and A+A collisions at the CERN SPS. The main components are 4 large-volume TPCs for tracking and particle identification via dE/dx. TOF scintillator arrays complement particle identification. Calorimeters for transverse energy determination and triggering, a detector for centrality selection in p+A collisions, and beam definition detectors complete the set-up. A description of all detector components is given with emphasis on new technical realizations. Performance and operational experience are discussed in particular with respect to the high track density environment of central Pb+Pb collisions

  7. The NA49 large acceptance hadron detector

    CERN Document Server

    Afanasiev, S V; Appelshäuser, H; Bächler, J; Barna, D; Barnby, L S; Bartke, Jerzy; Barton, R A; Betev, L; Bialkowska, H; Bieser, F; Billmeier, A; Blyth, C O; Böck, R K; Bormann, C; Bracinik, J; Brady, F P; Brockmann, R; Brun, R; Buncic, P; Caines, H L; Cebra, D; Cooper, G E; Cramer, J G; Csató, P; Cyprian, M; Dunn, J; Eckardt, V; Eckhardt, F; Empl, T; Eschke, J; Ferguson, M I; Fessler, H; Fischer, H G; Flierl, D; Fodor, Z; Frankenfeld, Ulrich; Foka, P Y; Freund, P; Friese, V; Ftácnik, J; Fuchs, M; Gabler, F; Gál, J; Ganz, R E; Gazdzicki, M; Gladysz-Dziadus, E; Grebieszkow, J; Günther, J; Harris, J W; Hegyi, S; Henkel, T; Hill, L A; Hlinka, V; Huang, I; Hümmler, H; Igo, G; Irmscher, D; Ivanov, M; Janik, R; Jacobs, P; Jones, P G; Kadija, K; Kolesnikov, V I; Kowalski, M; Lasiuk, B; Lévai, Peter; Liebicher, K; Lynen, U; Malakhov, A I; Margetis, S; Markert, C; Marks, C; Mayes, B W; Melkumov, G L; Mock, A; Molnár, J; Nelson, J M; Oldenburg, M; Odyniec, Grazyna Janina; Pálla, G; Panagiotou, A D; Pestov, Yu N; Petridis, A; Pikna, M; Pimpl, W; Pinsky, L; Piper, A; Porter, R J; Poskanzer, A M; Poziombka, S; Prindle, D J; Pühlhofer, F; Rauch, W; Reid, J G; Renfordt, R E; Retyk, W; Ritter, H G; Röhrich, D; Roland, C; Roland, G; Rudolph, H; Rybicki, A; Sammer, T; Sandoval, A; Sann, H; Schäfer, E; Schmidt, R; Schmischke, D; Schmitz, N; Schönfelder, S; Semenov, A Yu; Seyboth, J; Seyboth, P; Seyerlein, J; Siklér, F; Sitár, B; Skrzypczak, E; Squier, G T A; Stelzer, H; Stock, Reinhard; Strmen, P; Ströbele, H; Struck, C; Susa, T; Szarka, I; Szentpétery, I; Szymanski, P; Sziklai, J; Toy, M; Trainor, T A; Trentalange, S; Ullrich, T S; Vassiliou, Maria; Veres, G I; Vesztergombi, G; Vranic, D; Wang, F; Weerasundara, D D; Wenig, S; Whitten, C; Wieman, H H; Wienold, T; Wood, L; Yates, T A; Zimányi, J; Zhu, X Z; Zybert, R

    1999-01-01

    The NA49 detector is a wide acceptance spectrometer for the study of hadron production in p+p, p+A, and A+A collisions at the CERN SPS. The main components are 4 large volume TPCs for tracking and particle identification via $dE/dx$. TOF scintillator arrays complement particle identification. Calorimeters for transverse energy determination and triggering, a detector for centrality selection in p+A collisions, and beam definition detectors complete the set-up. A description of all detector components is given with emphasis on new technical realizations. Performance and operational experience are discussed in particular with respect to the high track density environment of central Pb+Pb collisions.

  8. Hotel na Vysočině

    OpenAIRE

    Machatka, Petr

    2013-01-01

    Diplomová práce s názvem Hotel na Vysočině řeší projektovou dokumentaci ve stupni pro provedení stavby. Hotel má tři nadzemní podlaží. Objekt je nepodsklepený. Zastřešení je provedeno plochou a šikmou střechou. Zdící systém POROTHERM s kontaktním zateplením expandovaným polystyrenem EPS -F. The master thesis named Hotel at Vysočina solves project documentation in the degree for building construction. The hotel has three floors. The object is without a cellar. As roofing is used a flat and ...

  9. O retorno do religioso na contemporaneidade

    Directory of Open Access Journals (Sweden)

    Tiago Ribeiro Nunes

    2008-12-01

    Full Text Available O presente trabalho pretende analisar os novos modos de relação, entre a civilização e o sagrado, que emergem no contexto da contemporaneidade. Partindo principalmente das formulações freudianas e lacanianas sobre o tema, nosso objetivo primordial ao longo deste artigo é estabelecer parâmetros para compreender a ocorrência do "retorno ao sagrado no exato momento em que a humanidade enfrenta crises cada vez mais profundas e permanentes. Tal empreendimento nos permitirá verificar até que ponto o fortalecimento dos movimentos religiosos pode ser considerado como uma das conseqüências da queda dos referenciais que se realiza na contemporaneidade.

  10. Estágio na Compta

    OpenAIRE

    Mendes, Dário Miguel dos Santos

    2017-01-01

    O presente documento descreve o trabalho realizado no segundo ano letivo do Mestrado em Produção de Conteúdos Digitais. Relatando um estágio decorrido na empresa tecnológica Compta S.A. Neste relatório é feita uma apresentação da empresa, bem como os seus objetivos como tal. De seguida, efetua-se um enquadramento do estágio no âmbito contextual dos conteúdos digitais, descrevendo as tecnologias utilizadas, necessárias à criação de aplicações para dispositivos móveis. São ainda apresentados...

  11. Solubility of NaNd(CO3)2.6H2O(c) in concentrated Na2CO3 and NaHCO3 solutions

    International Nuclear Information System (INIS)

    Rao, L.; Rai, D.; Felmy, A.R.; Fulton, R.W.; Novak, C.F.

    1996-01-01

    NaNd(CO 3 ) 2 x 6 H 2 O(c) was identified to be the final equilibrium solid phase in suspensions containing concentrated sodium carbonate (0.1 to 2.0 M) and sodium bicarbonate (0.1 to 1.0 M), with either NaNd(CO 3 ) 2 x 6 H 2 O(c) or Nd 2 (CO 3 ) 3 x xH 2 O(s) as initial solids. A thermodynamic model, based on Pitzer's specific into-interaction approach, was developed to interpret the solubility of NaNd(CO 3 ) 2 x 6 H 2 O(c) as functions of sodium carbonate and sodium bicarbonate concentrations. In this model, the solubility data of NaNd(CO 3 ) 2 x 6 H 2 O(c) were explained by assuming the formation of NdCO 3 + , Nd(CO 3 ) 2 - and Nd(CO 3 ) 3 3- species and invoking the specific ion interactions between Na + and Nd(CO 3 ) 3 3- . Ion interaction parameters for Na + -Nd(CO 3 ) 3 3- were developed to fit the solubility data. Based on the model calculations, Nd(CO 3 ) 3 3- was the predominant aqueous neodymium species in 0.1 to 2 M sodium carbonate and 0.1 to 1 M sodium bicarbonate solutions. The logarithm of the NaNd(CO 3 ) 2 x 6 H 2 O solubility product (NaNd(CO 3 ) 2 x 6 H 2 O(c)=Na + +Nd 3+ +2 CO 3 2- +6 H 2 O) was calculated to be -21.39. This model also provided satisfactory interpretation of the solubility data of the analogous Am(III) system in less concentrated carbonate and bicarbonate solutions. (orig.)

  12. Videogames e o aprender na complexidade

    Directory of Open Access Journals (Sweden)

    Paula Cristina Turcatto

    2016-06-01

    Full Text Available Ao conceber-se esta pesquisa, levou-se em consideração que cada ser humano aprende do seu modo pessoal e único, portanto, a proposta é pensar os videogames na sua relação com o Paradigma da Complexidade. Esta pesquisa teve como objetivo proporcionar um ambiente de encontro com diversos jogos de videogame, buscando instaurar a experimentação do novo, a abertura para o conhecer, ao habitar espaços inventivos, que valorizam a plasticidade e flexibilidade. Trata-se de uma pesquisa qualitativa, pois se propôs a trabalhar com os aspectos subjetivos como uma dimensão inseparável do conhecer. Foram 8 sujeitos de pesquisa – adolescentes – com os quais foram realizados 15 encontros, nos quais os mesmos estiveram em contato com diversos jogos de videogame. Foram utilizados diários de bordo para o registro das vivências, ancorados na metodologia cartográfica para tratamento dos registros. Os videogames propiciaram espaços para a emergência de diferentes formas de vivenciar a narrativa. Apesar de os jogos serem pré-moldados, os percursos produzidos, assim como as produções simbólicas frente ao contexto do jogo foram individuais. Jogar videogame relacionou-se ao posicionamento criador, de escrever as circunstâncias sob as quais as ações do jogo refletiram nas experiências vivenciadas pelo jogador.

  13. Insulin regulation of (Na+, K+)-ATPase

    International Nuclear Information System (INIS)

    Lytton, J.

    1985-01-01

    This thesis describes an investigation into the mechanism of insulin stimulation of (Na + ,K + )=ATPase in rat adipocytes. Two molecular forms of the catalytic subunit of the enzyme were identified and denoted α and α(+), due to their similarity to those isozymes previously described from rat brain. Insulin specifically stimulated the α(+) form of the enzyme. The two forms of the enzyme had quite different affinities for intracellular sodium ion; insulin affected only the lower affinity of α(+), shifting it toward a higher value. However, the sodium affinity of (Na + ,K + )-ATPase activity in isolated membranes was equally high for both forms of the enzyme. This suggests that the difference in sodium affinity between the two forms observed in the cell is not inherent within the structure of the sodium pump, but must depend upon a selective interaction with another molecule which has been lost upon membrane isolation. Immunoprecipitation of both the catalytic subunits either from extracts of whole cells which had been labelled with [ 32 P] orthophosphate, or from membranes which had been labelled with γ-[ 32 P]ATP demonstrated that less than 1 in 100 molecules had a covalently bound phosphate insulin had no influence on this value. The amino terminal sequences of the first 4 amino acids of the catalytic subunits of both α (isolated from rat kidney) and α(+) (from rat brainstem axolemma) were determined. The result shows two highly homologous but clearly different molecules. It can thus be concluded that the insulin sensitive version of the enzyme is not derived from the common α form by a post-translational modification

  14. Porta-enxertos utilizados na citricultura

    Directory of Open Access Journals (Sweden)

    Schäfer Gilmar

    2001-01-01

    Full Text Available A muda cítrica é o insumo mais importante na formação de um pomar. As características mais importantes da muda cítrica são a origem do enxerto e do porta-enxerto, a qualidade do sistema radicular e a sua sanidade. Os porta-enxertos são capazes de influenciar várias características horticulturais e sanitárias nas árvores e nos frutos cítricos, como: sólidos solúveis totais, tamanho da copa e do fruto, resistência a moléstias e ao frio, distribuição da raízes, etc. O principal porta-enxerto utilizado no Brasil (cerca de 80% é o limoeiro ?Cravo? (Citrus limonia Osbeck cv. Cravo. No Rio Grande do Sul, mais especificamente, destaca-se o Poncirus trifoliata (L. Raf em mais de 90% dos pomares. Isso torna a citricultura vulnerável ao surgimento de moléstias que afetem estes porta-enxertos, como ocorreu na década de 40 em todo o Brasil com a 'Tristeza' dos citros em plantas enxertadas sobre laranjeira azeda, e, mais recentemente, com o 'declínio'. Assim, o conhecimento das características dos diversos porta-enxertos e de algumas particularidades do uso destes é de grande importância para a diversificação e escolha do porta-enxerto a ser utilizado pelo citricultor.

  15. PERSPECTIVA MULTIDIMENSIONAL DO TRABALHO NA CONTEMPORANEIDADE

    Directory of Open Access Journals (Sweden)

    Lilian Carminatti

    2015-12-01

    Full Text Available O objetivo deste estudo é analisar a evolução do tema trabalho e novas formas de flexibilização das relações laborais que proporcionam identidade, significado e bem-estar. O trabalho, como uma atividade prazerosa, passa por uma mudança de postura das pessoas frente à atividade ocupacional, a partir do autoconhecimento, planejamento de carreira e de uma jornada de trabalho que vislumbre a melhora na qualidade de vida. A promoção do bem-estar presume a articulação entre as relações de trabalho atravessadas pelo sistema capitalista e a importância de equilibrar necessidades individuais e a competitividade organizacional. Como elementos balizadores surgem: a relação com os significados do trabalho, o planejamento de carreira e pós-carreira e a conexão entre valores pessoais e organizacionais. Adotou-se para a pesquisa uma estratégia metodológica qualitativa que se propõe a investigar a partir da exploração e descrição as dimensões do tema trabalho na sociedade contemporânea. Dessa forma, a promoção do bem-estar e o planejamento de carreira devem ser tratados como planejamento de vida durante todo o período funcional, a partir de uma visão multidimensional do colaborador inserida em um amplo contexto cultural e social que ultrapassa o ambiente organizacional.

  16. Mercury's Na Exosphere from MESSENGER Data

    Science.gov (United States)

    Killen, Rosemary M.; Burger, M. H.; Cassidy, T. A.; Sarantos, M.; Vervack, R. J.; McClintock, W. El; Merkel, A. W.; Sprague, A. L.; Solomon, S. C.

    2012-01-01

    MESSENGER entered orbit about Mercury on March 18, 2011. Since then, the Ultraviolet and Visible Spectrometer (UWS) channel of MESSENGER's Mercury Atmospheric and Surface Composition Spectrometer (MASCS) has been observing Mercury's exosphere nearly continuously. Daily measurements of Na brightness were fitted with non-uniform exospheric models. With Monte Carlo sampling we traced the trajectories of a representative number of test particles, generally one million per run per source process, until photoionization, escape from the gravitational well, or permanent sticking at the surface removed the atom from the simulation. Atoms were assumed to partially thermally accommodate on each encounter with the surface with accommodation coefficient 0.25. Runs for different assumed source processes are run separately, scaled and co-added. Once these model results were saved onto a 3D grid, we ran lines of sight from the MESSENGER spacecraft :0 infinity using the SPICE kernels and we computed brightness integrals. Note that only particles that contribute to the measurement can be constrained with our method. Atoms and molecules produced on the nightside must escape the shadow in order to scatter light if the excitation process is resonant-light scattering, as assumed here. The aggregate distribution of Na atoms fits a 1200 K gas, with a PSD distribution, along with a hotter component. Our models constrain the hot component, assumed to be impact vaporization, to be emitted with a 2500 K Maxwellian. Most orbits show a dawnside enhancement in the hot component broadly spread over the leading hemisphere. However, on some dates there is no dawn/dusk asymmetry. The portion of the hot/cold source appears to be highly variable.

  17. LUZ, MELATONINA E ESTRESSE OXIDATIVO NA PISCICULTURA

    Directory of Open Access Journals (Sweden)

    Claudio Alberto Gellis de Mattos Dias

    2013-12-01

    Full Text Available Em peixes, como nos mamíferos, partes do sistema nervoso estão envolvidas em mecanismos para regulação dos sistemas corporais em sintonia com o meio. O fotoperíodo é traduzido em informações fisiológicas a partir da secreção de melatonina.Parece não haver barreiras morfofisiológicas para esta indolamina, isto é, a melatonina perfunde-se rapidamente em cada célula do organismo e em alguns casos interage com receptores e membrana situados na superfície celular, e parece estar ligada à ingestão de alimentos, crescimento e atividade locomotora de peixes. São moléculas importantes metabolizando espécies reativas de oxigênio a produtos inativos e, portanto, reduzindo o dano oxidativo.Este trabalho tem por objetivo fazer um breve levantamento em artigos recentes sobre luminosidade, melatonina e o estresse oxidativo em peixes, e correlaciona-los com piscicultura. Concluímos que a luminosidade parece estar ligada a produção de melatonina, e esta molécula antioxidante, que favorece a redução do estresse oxidativo, parecem melhorar o desempenho na produção de peixes em criadouros. Palavras-chave: Melatonina, estresse oxidativo, piscicultura. DOI: http://dx.doi.org/10.18561/2179-5746/biotaamazonia.v3n3p169-176

  18. Diffusion of calcium in pure and doped NaCl; Diffusion du calcium dans NaCl pur et dope

    Energy Technology Data Exchange (ETDEWEB)

    Slifkin, L; Brebec, G [Commissariat a l' Energie Atomique, Saclay (France). Centre d' Etudes Nucleaires

    1969-07-01

    We have determined, by diffusion experiments of Ca in pure and doped NaCl, the activation energy for the calcium jumps and the binding energy between calcium ion and vacancy. (authors) [French] Nous avons determine, par des mesures de diffusion du Ca dans NaCl pur et NaCl dope avec CaCl{sub 2}, l'energie d'activation relative aux sauts du calcium et l'energie de liaison lacune-calcium. (auteurs)

  19. Mechanism of μ-conotoxin PIIIA binding to the voltage-gated Na+ channel NaV1.4.

    Directory of Open Access Journals (Sweden)

    Rong Chen

    Full Text Available Several subtypes of voltage-gated Na+ (NaV channels are important targets for pain management. μ-Conotoxins isolated from venoms of cone snails are potent and specific blockers of different NaV channel isoforms. The inhibitory effect of μ-conotoxins on NaV channels has been examined extensively, but the mechanism of toxin specificity has not been understood in detail. Here the known structure of μ-conotoxin PIIIA and a model of the skeletal muscle channel NaV1.4 are used to elucidate elements that contribute to the structural basis of μ-conotoxin binding and specificity. The model of NaV1.4 is constructed based on the crystal structure of the bacterial NaV channel, NaVAb. Six different binding modes, in which the side chain of each of the basic residues carried by the toxin protrudes into the selectivity filter of NaV1.4, are examined in atomic detail using molecular dynamics simulations with explicit solvent. The dissociation constants (Kd computed for two selected binding modes in which Lys9 or Arg14 from the toxin protrudes into the filter of the channel are within 2 fold; both values in close proximity to those determined from dose response data for the block of NaV currents. To explore the mechanism of PIIIA specificity, a double mutant of NaV1.4 mimicking NaV channels resistant to μ-conotoxins and tetrodotoxin is constructed and the binding of PIIIA to this mutant channel examined. The double mutation causes the affinity of PIIIA to reduce by two orders of magnitude.

  20. Anisotropy and polarization in charge changing collisions of C4+ with Na(3s) and laser aligned Na(3p)

    NARCIS (Netherlands)

    Hoekstra, R; Morgenstern, R; Olson, RE

    1996-01-01

    Absolute cross sections for C3+(6-->5) emission at 465.7 nm after collisions of C4+ ions with ground state Na(3s) and laser excited aligned Na(Sp) atoms are measured over the collision energy range of 3-7 keV amu(-1). For Na(3s) polarizations are observed by measuring the linear polarization of the

  1. Crystal structure of polyphosphates NaCd(PO3)3 and NaMn(PO3)3

    International Nuclear Information System (INIS)

    Murashova, E.V.; Chudinova, N.N.

    1997-01-01

    Crystal structure of NaCd(PO 3 ) 3 (1) and NaMn(PO 3 ) 3 (2) isostructural polyphosphates was determined for twin samples. Rhombic lattice parameters of (1): a = 14.678, b = 14.669, c = 14.705 A, sp. gr. P2 1 2 1 2 1 , Z = 16. The structure of compounds is of frame type. Polyphosphate chain with repetition period of 24 PO 4 tetrahedrons contacts with NaO 6 and M 2 O 6 octahedrons by means of common oxygen vertices. Similarities and differences in structure of mentioned polyphosphates and earlier analyzed NaMg(PO 3 ) 3 polyphosphate are noted [ru

  2. UTJECAJ POZITIVNE DISKRIMINACIJE NA UKLJUČIVANJE ŽENA NA TRŽIŠTE RADA U REPUBLICI HRVATSKOJ

    OpenAIRE

    Dovranić, Dora; Katavić, Ivica

    2016-01-01

    U početku 21. stoljeća često se koristi pojam pozitivne (afirmativne) diskriminacije. Pozitivna diskriminacija mjera je koju poduzima vlada, neka organizacija ili korporacija s ciljem da se smanje nejednakosti u društvu nastale upravo diskriminacijom, na način da se pružaju određene povlastice onima koji su pretrpjeli neku vrstu diskriminacije. Nastala je u Sjedinjenim Američkim Državama na inicijativu predsjednika Kennedyja, Johnsona i Nixona. Diskriminacija, nažalost, ima mnogo oblika, a ne...

  3. 43. Calmodulin regulating calcium sensitivity of Na channels

    Directory of Open Access Journals (Sweden)

    R. Vegiraju

    2016-07-01

    Full Text Available By extrapolating information from existing research and observing previous assumptions regarding the structure of the Na Channel, this experiment was conducted under the hypothesis that the Na Channel is in part regulated by the calmodulin protein, as a result proving calcium sensitivity of the Na Channel. Furthermore, we assume that there is a one to one stoichiometry between the Na Channel and the Calmodulin. There has been extensive research into the functionality and structure of sodium ion channels (Na channels, as several diseases are associated with the lack of regulation of sodium ions, that is caused by the disfunction of these Na channels. However, one highly controversial matter in the field is the importance of the protein calmodulin (CaM and calcium in Na channel function. Calmodulin is a protein that is well known for its role as a calcium binding messenger protein, and that association is believed to play an indirect role in regulating the Na channel through the Na channel’s supposed calcium sensitivity. While there are proponents for both sides, there has been relatively little research that provides strong evidence for either case. In this experiment, the effect of calmodulin on NaV 1.5 is tested by preparing a set of cardiac cells (of the human specie with the NaV 1.5 C-Termini and CaM protein, which were then to be placed in solutions with varying concentrations of calcium. We took special care to test multiple concentrations of calcium, as previous studies have tested very low concentrations, with Manu Ben-Johny’s team from the John Hopkins laboratory in particular testing up to a meager 50 micromolar, despite producing a well-respected paper (By comparison, the average Na channel can naturally sustain a concentration of almost 1-2 millimolar and on some occasions, reaching even higher concentrations. After using light scattering and observing the signals given off by the calcium interacting with these Nav1.5/Ca

  4. Impact of childhood stress on psychopathology Impacto de estresse na infância na psicopatologia

    Directory of Open Access Journals (Sweden)

    Elisa Brietzke

    2012-12-01

    Full Text Available OBJECTIVE: Advances in our knowledge of mental disorder (MD genetics have contributed to a better understanding of their pathophysiology. Nonetheless, several questions and doubts persist. Recent studies have focused on environmental influences in the development of MDs, and the advent of neuroscientific methodologies has provided new perspectives. Early life events, such as childhood stress, may affect neurodevelopment through mechanisms such as gene-environment interactions and epigenetic regulation, thus leading to diseases in adulthood. The aim of this paper is to review the evidence regarding the role of the environment, particularly childhood stress, in the pathophysiology of MD. METHODOLOGY: We reviewed articles that evaluated environmental influences, with a particular focus on childhood trauma, brain morphology, cognitive functions, and the development of psychopathology and MD. RESULTS AND CONCLUSION: MRI studies have shown that exposure to trauma at an early age can result in several neurostructural changes, such as the reduction of the hippocampus and corpus callosum. Cognitive performance and functioning are also altered in this population. Finally, childhood stress is related to an increased risk of developing MD such as depression, bipolar disorder, schizophrenia and substance abuse. We conclude that there is robust evidence of the role of the environment, specifically adverse childhood experiences, in various aspects of MD.OBJETIVO: Avanços no conhecimento da genética dos transtornos mentais (TM contribuíram para um melhor entendimento de suas bases fisiopatológicas. No entanto, dúvidas e questões ainda persistem. Estudos recentes têm se concentrado nas influências do ambiente no desenvolvimento de TM, e o advento de metodologias neurocientíficas oferece novas perspectivas. Eventos precoces de vida, como estresse na infância, podem ser capazes de alterar o neurodesenvolvimento através de mecanismos como intera

  5. Measurement of direct CP-violation with the experiments NA31 and NA48 at CERN

    International Nuclear Information System (INIS)

    Renk, B.

    1992-01-01

    The NA31 experiment has measured the CP violation parameter var-epsilon '/var-epsilon. The result of data collected in 1988 is Re(var-epsilon '/var-epsilon)=(1.7±1.0)x10 -3 . A preliminary result of data collected in 1989 is Re(var-epsilon '/var-epsilon)=(2.1±0.9)x10 -3 . Combining these two results with the original result from the 1986 data set we obtain Re(var-epsilon '/var-epsilon)=(2.3±0.7)x10 -3 , which is a more than three standard deviation evidence for direct CP violation. A new experiment NA48 is under construction which aims for a significant reduction of the statistical and the systematical errors in order to reach a combined error not exceeding 2x10 -4

  6. O Platonismo de Russell na metafísica e na matemática

    Directory of Open Access Journals (Sweden)

    Guido Imaguire

    2005-06-01

    Full Text Available Neste artigo, analiso o surgimento e a superação do Platonismo em B. Russell, tanto na sua filosofia da matemática como na sua metafísica. Começo por explicitar os argumentos que levaram Russell a aderir ao chamado "Platonismo Proposicional" - posição que será tecnicamente relevante na definição de números. Na seção seguinte, discutirei até que ponto a teoria das descrições definidas determina, necessariamente, uma adesão ao nominalismo, e as dificuldades que surgem para o logicismo conseqüentes do abandono do platonismo. Finalmente, mostrarei como a posição madura de Russell caracteriza-se mais como um reducionismo do que propriamente como um nominalismo, e como este é fundado no princípio do mínimo vocabulário.In this paper, I analyze the emergence and the overcoming of Platonism both in Russell's philosophy of mathematics and his metaphysics. I begin by examining the arguments which led Russell to endorse a position that I term "Propositional Platonism" - this position proves to be relevant for Russell's definition of numbers. In the following section, I address the question of the extent to which Russell's theory of descriptions implies the acceptance of nominalism. Moreover, I examine the difficulties which arise for logicism, if it no longer goes hand in hand with platonism. Finally, I argue argue that Russell's mature position is to be characterized as a form of reductionism rather than as a variant of nominalism

  7. LASERTERAPIA NA INFLAMAÇÃO PULMONAR EXPERIMENTAL EM RATTUS NORVEGICUS OCASIONADO PELA PAPAÍNA

    Directory of Open Access Journals (Sweden)

    Diego Rodrigues Pessoa

    2017-01-01

    Full Text Available Resumo: A Doença Pulmonar Obstrutiva Crônica (DPOC é caracterizada pela limitação do fluxo aéreo decorrente da dilatação dos espaços aéreos distais aos bronquíolos terminais. Analisar os efeitos da laserterapia quanto ao processo cicatricial na lesão pulmonar experimental em Rattus Novergicus. Utilizaram-se trinta animais agrupados em três grupos de dez animais: grupo controle (GC (não recebeu nada, grupo DPOC (GD (foi pulverizado 3 doses de papaína 3mg/kg e grupo DPOC + Laser (GDL (após 7 dias da indução da lesão com papaína foi tratado com laser de 660 nm durante 15 dias.Para analise dos resultados foi realizado o lavado broncoalveolar. Quanto ao Lavado: GC (número de células normais, GD (aumento de células inflamatórias e GDL (diminuição de células inflamatórias. A laserterapia diminui o numero de células inflamatórias, entretanto, não possui efeito reconstrutor do parênquima pulmonar apenas estabiliza a lesão comprovando sua ação anti-inflamatória.

  8. Isolation and preliminary function analysis of a Na + /H + antiporter ...

    African Journals Online (AJOL)

    A full-length cDNA Na+/H+ antiporter gene (MzNHX1) was isolated from Malus zumi according to the homologous Na+/H+ antiporter gene region in plants. Sequence analysis indicated that the cDNA was 2062 bp in length, including an open reading frame (ORF) of 1629 bp, which encoded a predicted polypeptide of 542 ...

  9. Transepithelial Na+ transport and the intracellular fluids: a computer study.

    Science.gov (United States)

    Civan, M M; Bookman, R J

    1982-01-01

    Computer simulations of tight epithelia under three experimental conditions have been carried out, using the rheogenic nonlinear model of Lew, Ferreira and Moura (Proc. Roy. Soc. London. B 206:53-83, 1979) based largely on the formulation of Koefoed-Johnsen and Ussing (Acta Physiol. Scand. 42: 298-308. 1958). First, analysis of the transition between the short-circuited and open-circuited states has indicated that (i) apical Cl- permeability is a critical parameter requiring experimental definition in order to analyze cell volume regulation, and (ii) contrary to certain experimental reports, intracellular Na+ concentration (ccNa) is expected to be a strong function of transepithelial clamping voltage. Second, analysis of the effects of lowering serosal K+ concentration (csK) indicates that the basic model cannot simulate several well-documented observations; these defects can be overcome, at least qualitatively, by modifying the model to take account of the negative feedback interaction likely to exist between the apical Na+ permeability and ccNa. Third, analysis of the strongly supports the concept that osmotically induced permeability changes in the apical intercellular junctions play a physiological role in conserving the body's stores of NaCl. The analyses also demonstrate that the importance of Na+ entry across the basolateral membrane is strongly dependent upon transepithelial potential, cmNa and csK; under certain conditions, net Na+ entry could be appreciably greater across the basolateral than across the apical membrane.

  10. A mudança organizacional na teoria administrativa

    OpenAIRE

    Silveira Júnior, Aldery; Oliveira, Waldyr Viegas de

    1996-01-01

    Discorre sobre a mudança organizacional na teoria administrativa, abordando a natureza da mudança, como ela se insere no contexto das organizações e como ela se desenvolveu na história da administração.

  11. High resolution laser spectroscopy of the D lines of on-line produced 21Na, 22Na, 24Na, 25Na using a new high sensitivity method of detection of optical resonances

    International Nuclear Information System (INIS)

    Huber, G.; Thibault, G.; Klapisch, R.; Duong, H.T.; Vialle, J.L.; Pinard, I.; Juncar, P.; Jacquinot, P.

    1975-01-01

    A polyisotopic sodium beam of 21 - 25 Na, produced by spallation of Al, was illuminated by a tunable dye laser. The atomic beam, analyzed by a sixpole magnet is then ionized and detected after a mass spectrometer. The results are the isotope shifts, nuclear magnetic moment and quadrupole moment of 25 Na [fr

  12. Numerična in eksperimentalna analiza delovanja Teslinega ventilatorja

    OpenAIRE

    Lukačič, Rajko

    2017-01-01

    Nikola Tesla je patentiral ventilator, ki deluje na principu trenja. V diplomskem delu je opisano delovanje Teslinega ventilatorja in teoretično ozadje njegovega delovanja z namenom zmanjševanja hrupa. V sami raziskavi smo s programom Ansys izdelali numerični model, ki temelji na turbulentnem modelu k-

  13. Risbjerg: SF vandt valgkampen, NA og R tabte

    DEFF Research Database (Denmark)

    Thomsen, Søren Risbjerg

    2007-01-01

    ANALYSE: Endnu engang flyttede en valgkamp for alvor stemmer. SF gik undervejs 27 pct. frem, mens NA gik 34 pct. tilbage og R 26 pct. Udgivelsesdato: 25. november......ANALYSE: Endnu engang flyttede en valgkamp for alvor stemmer. SF gik undervejs 27 pct. frem, mens NA gik 34 pct. tilbage og R 26 pct. Udgivelsesdato: 25. november...

  14. MCHANGO WA MWALIMU J.K. NYERERE KATIKA TAFSIRI NA ...

    African Journals Online (AJOL)

    Kwa kuzingatia tafsiri mbili za J.K. Nyerere, Julius Kaizer (1963) na Mabepari wa Venus (1969), makala inaeleza: (i) kwa nini Mwalimu Nyerere alitafsiri maandishi ya Shakespeare, (ii) ufanisi wa tafsiri zake, na (iii) mchango wa tafsiri hizo. Makala inaonyesha kuwa tafsiri hizo zinazingatia mbinu za kisemantiki zaidi kuliko ...

  15. Kuingiliana kwa Lugha ya Kiswahili na Kiingereza: Uswahilishaji wa ...

    African Journals Online (AJOL)

    Kuingiliana kwa lugha ni taaluma katika uwanja wa isimu inayohusu lugha zinazoingiliana na kuathiriana. Kuingiliana kwa lugha sio jambo jipya katika dunia. Watu ambao ndio watumiaji wa lugha wamesababisha lugha kuiingiliana waliposafiri au kuhama sehemu moja hadi nyingine kutokana na sababu za kiuchumi, ...

  16. Ufundishaji wa Kusoma na Kuandika Kiswahili: Uzoefu wa Idara ya ...

    African Journals Online (AJOL)

    Makala haya yanahusu shughuli za kufundisha Kiswahili kama lugha ya kigeni katika Chuo Kikuu cha Sebha nchini Libya. Kwanza inaeleza historia ya Kiswahili – yaani kilianza lini kufundishwa kwa madhumuni gani na nani walikuwa wanzilishi. Halikadhalika makala ya naeleza utaratibu uliowekwa na idara ili kuweza ...

  17. Juhudi za Vyombo vya Habari katika Kukuza na Kueneza Kiswahili ...

    African Journals Online (AJOL)

    Vyombo vya habari ni asasi muhimu sana katika kukuza na kueneza lugha yoyote ile, hasa katika enzi hii ya utandawazi. Vyombo hivyo ni kama vile idhaa za redio, televisheni na magazeti. Katika nchi ya Kenya kuna vyombo vya habari vinavyotoa huduma anuwai kwa ajili ya kutosheleza mahitaji ya wateja wao. Katika ...

  18. Substrate Specificity of Na+,Cl-(HCO3-)-ATPase.

    Science.gov (United States)

    Yurkiv, V A; Melikhov, V I; Shubin, V S

    2016-09-01

    We studied substrate specificity of Na + ,Cl - (HCO 3 - )-ATPase. In most cases, replacement of ATP for other phosphate-containing substances resulted in not only pronounced suppression of phosphohydrolase reactions, but also dramatic changes of their responsiveness to the stimulating effect of monovalent ions. The data showed that Na + ,Cl - (HCO 3 - )-ATPase is a highly specific enzyme for ATP.

  19. Optimization and kinetics decomposition of monazite using NaOH

    International Nuclear Information System (INIS)

    MV Purwani; Suyanti; Deddy Husnurrofiq

    2015-01-01

    Decomposition of monazite with NaOH has been done. Decomposition performed at high temperature on furnace. The parameters studied were the comparison NaOH / monazite, temperature and time decomposition. From the research decomposition for 100 grams of monazite with NaOH, it can be concluded that the greater the ratio of NaOH / monazite, the greater the conversion. In the temperature influences decomposition 400 - 700°C, the greater the reaction rate constant with increasing temperature greater decomposition. Comparison NaOH / monazite optimum was 1.5 and the optimum time of 3 hours. Relations ratio NaOH / monazite with conversion (x) following the polynomial equation y = 0.1579x 2 – 0.2855x + 0.8301 (y = conversion and x = ratio of NaOH/monazite). Decomposition reaction of monazite with NaOH was second orde reaction, the relationship between temperature (T) with a reaction rate constant (k), k = 6.106.e - 1006.8 /T or ln k = - 1006.8/T + 6.106, frequency factor A = 448.541, activation energy E = 8.371 kJ/mol. (author)

  20. Sepsis does not alter red blood cell glucose metabolism or Na+ concentration: A 2H-, 23Na-NMR study

    International Nuclear Information System (INIS)

    Hotchkiss, R.S.; Song, S.K.; Ling, C.S.; Ackerman, J.J.; Karl, I.E.

    1990-01-01

    The effects of sepsis on intracellular Na+ concentration ([Na+]i) and glucose metabolism were examined in rat red blood cells (RBCs) by using 23Na- and 2H-nuclear magnetic resonance (NMR) spectroscopy. Sepsis was induced in 15 halothane-anesthetized female Sprague-Dawley rats by using the cecal ligation and perforation technique; 14 control rats underwent cecal manipulation without ligation. The animals were fasted for 36 h, but allowed free access to water. At 36 h postsurgery, RBCs were examined by 23Na-NMR by using dysprosium tripolyphosphate as a chemical shift reagent. Human RBCs from 17 critically ill nonseptic patients and from 7 patients who were diagnosed as septic were also examined for [Na+]i. Five rat RBC specimens had [Na+]i determined by both 23Na-NMR and inductively coupled plasma-atomic emission spectroscopy (ICP-AES). For glucose metabolism studies, RBCs from septic and control rats were suspended in modified Krebs-Henseleit buffer containing [6,6-2H2]glucose and examined by 2H-NMR. No significant differences in [Na+]i or glucose utilization were found in RBCs from control or septic rats. There were no differences in [Na+]i in the two groups of patients. The [Na+]i determined by NMR spectroscopy agreed closely with measurements using ICP-AES and establish that 100% of the [Na+]i of the RBC is visible by NMR. Glucose measurements determined by 2H-NMR correlated closely (correlation coefficient = 0.93) with enzymatic analysis. These studies showed no evidence that sepsis disturbed RBC membrane function or metabolism

  1. Experiments on cold trap regeneration by NaH decomposition

    International Nuclear Information System (INIS)

    McPheeters, C.C.; Skladzien, S.B.; Raue, D.J.

    1979-10-01

    Cold trap regeneration may be very important in future LMFBRs because of the expected high hydrogen source from the steam generators. This hydrogen precipitates as NaH in the cold trap and may fill the trap within one year of operation. Several methods of cold trap regeneration were considered, but the simplest and least expensive appears to be decomposition of NaH under vacuum at elevated temperatures. Experiments were done to assess the feasibility of this method for cold trap regeneration. Small-scale simulated cold traps (SCT) were located with NaH and NaH plus Na 2 O, and were heated both under vacuum and under a sweep gas at 100 kPa. The evolved hydrogen was converted to water by a CuO bed and collected in a weighting tube

  2. Na,K-pump modulates intercellular communication in vascular wall

    DEFF Research Database (Denmark)

    Matchkov, Vladimir; Nilsson, Holger; Aalkjær, Christian

      Ouabain, a specific inhibitor of the Na,K-pump, has previously been shown to interfere with intercellular communication. Here we test the hypothesis that the communication between vascular smooth muscle cells (SMCs) is regulated through an interaction between the Na,K-pump and the Na...... were used as a model for electrical coupling of SMCs by measuring membrane capacitance (Cm). SMCs were uncoupled (evaluated by inhibition of vasomotion and desynchronization of calcium transients in vascular wall, or by reduction to half of Cm measured in paired A7r5 cells) when the Na,K-pump...... was inhibited either by a low concentration of ouabain or by ATP depletion. Uncoupling with ouabain was associated with a localized increase of intracellular calcium in discrete sites near the plasma membrane. Reduction of Na,K-pump activity by removal of extracellular potassium also uncoupled cells, but only...

  3. Recent results from the NA62 experiment at CERN

    CERN Document Server

    Aliberti, Riccardo

    2016-01-01

    NA62 is a fixed target experiment located at the CERN SPS which aims to perform flavour physics studies in the charged kaon sector with an unprecedented precision. Due to the abundance of kaon decays with a po in the final state, NA62 is also a perfect environment to measure the neutral pion characteristics. NA62 collected a large sample of charged kaon decays with a highly efficient trigger for decays into electrons in 2007. We report about the measurement of the po electromagnetic transition form factor slope parameter in the time-like region. Between 2008 and 2014 the NA62 apparatus underwent an intense upgrade phase to improve the physics sensitivity of the experiment to precisely measure the Br (K+ !p+n ¯ n). NA62 took data in pilot runs in 2014 and 2015 reaching the final designed beam intensity. The quality of data acquired in view of the final measurement is presented.

  4. The New Readout System of the NA62 LKr Calorimeter

    CERN Document Server

    Ceccucci, A; Farthouat, P; Lamanna, G; Rouet, J; Ryjov, V; Venditti, S

    2015-01-01

    The NA62 experiment [1] at CERN SPS (Super Proton Synchrotron) accelerator aims at studying Kaon decays with high precision. The high resolution Liquid Krypton (LKr) calorimeter, built for the NA48 [2] experiment, is a crucial part of the photon-veto system; to cope with the demanding NA62 re- quirements,itsback-endelectron icshadtobecompletelyrenewed. The new readout system is based on the Calorimeter REAdout Module (CREAM) [3], a 6U VME board whose design and pro- duction was sub-contracted to CAEN [4], with CERN NA62 group continuously supervising the de velopment and production phase. The first version of the board was delivered by the manufacturer in March 2013 and, as of June 2014, the full board production is ongoing. In addition to describing the CREAM board, all aspects of the new LKr readout system, including its integration within the NA62 TDAQ scheme, will be treated.

  5. Crystal Structure of Na3MoCl6

    Directory of Open Access Journals (Sweden)

    Martin Beran

    2011-07-01

    Full Text Available The ternary chloride Na3MoCl6 is obtained as red crystals from a disproportionation reaction of molybdenum dichloride, {Mo6}Cl12, in an acidic NaCl/AlCl3 melt at 350 °C. The crystal structure (trigonal, P-31c, a = 687.1(1, c = 1225.3(2 pm, Z = 2, V = 501,0(1 106 pm3 is that of Na3CrCl6: within a hexagonal closest-packing of chloride ions two thirds of the octahedral voids are filled between the AB double layers with Na+/Mo3+, and between the BA layers with Na+.

  6. Dynamic polarizabilities and Van der Waals coefficients for alkali atoms Li, Na and alkali dimer molecules Li2, Na2 and NaLi

    Science.gov (United States)

    Mérawa, M.; Dargelos, A.

    1998-07-01

    The present paper gives an account of investigations of the polarizability of the alkali atoms Li, Na, diatomics homonuclear and heteronuclear Li2, Na2 and NaLi at SCF (Self Consistent Field) level of approximation and at correlated level, using a time Time-Dependent Gauge Invariant method (TDGI). Our static polarizability values agree with the best experimental and theoretical determinations. The Van der Waals C6 coefficients for the atom-atom, atom-dimer and dimer-dimer interactions have been evaluated. Les polarisabilités des atomes alcalins Li, Na, et des molécules diatomiques homonucléaires et hétéronucléaire Li2, Na2 et NaLi, ont été calculées au niveau SCF (Self Consistent Field) et au niveau corrélé à partir d'une méthode invariante de jauge dépendante du temps(TDGI). Nos valeurs des polarisabilités statiques sont en accord avec les meilleurs déterminations expérimentales et théoriques. Les coefficients C6 de Van de Waals pour les interactions atome-atome, atome-dimère et dimère-dimère ont également été évalués.

  7. Fanfictions: leitura e escrita na cibercultura

    Directory of Open Access Journals (Sweden)

    Monica do Amparo Silva

    2017-12-01

    Full Text Available A condição letrada é um fenômeno de natureza complexa e multifacetada. Organiza-se em torno de um conjunto de gestos e comportamentos diversificados, de competências e habilidades heterogêneas, de objetos histórica e socialmente diferenciados; é construída por meio de um conjunto de práticas e de uma rede de instituições, agentes e materiais; responsável por grandes divisões no interior da sociedade e um dos fatores que poderiam transformá-la. O ingresso na cultura escrita por sociedades ocidentais já foi considerado uma das principais evoluções da era moderna. Dominar a escrita era também a produzir. Contemporaneamente, uma sociedade civilizada chega a exigir de seus membros o domínio e utilização da leitura de variados suportes em variadas formas (pois cada suporte acaba por desenvolver um modo de leitura peculiar. Pode-se, pois, inferir que o ato de ler é um ato de esforço e concentração que também exige reflexão. Dessa forma, a leitura assume o papel de um processo de disciplina intelectual, exigindo uma posição crítica daquele que é o leitor. Os ciberjovens não só consomem a leitura e toda produção midiática. Eles interagem com essa produção e realizam uma recriação cultural com identidade e público próprios denominada fanfiction cuja escrita pode ser divulgada em diferentes plataformas do ciberespaço sob diversos gêneros textuais. Este artigo é resultado da reflexão baseada na observação de um app que permite a escrita/ leitura e a divulgação dessa produção.

  8. Kusheh, na minem Fatu, en mi na koko farmer Hello, I am Fatu and I am a cocoa farmer

    NARCIS (Netherlands)

    Witteveen, L.M.; Goris, Margriet; Lie, R.; Ingram, V.J.

    2016-01-01

    This document reports on the development of a prototype Digital Farmer Field School (DFFS) called Kusheh, na minem Fatu, en mi na koko farmer (“Hello, I am Fatu and I am a cocoa farmer”). The DFFS provides an ICT-based alternative to traditional agricultural extension. More specifically, it offers a

  9. Rescue of Na+ and H+ binding in Na+,K+-ATPase M8 aspartate mutants by secondary mutation

    DEFF Research Database (Denmark)

    Holm, Rikke; Einholm, Anja P.; Andersen, Jens Peter

    A mutation replacing the aspartate in transmembrane segment M8 in the a3-isoform of Na,K-ATPase with asparagine has been found in patients with rapid-onset dystonia parkinsonism or alternating hemiplegia of childhood. This aspartate may be a critical Na+ coordinating residue, but the crystal......-isoforms of Na,K-ATPase, and much smaller effects were seen for other mutations to the M8 aspartate, which were less disruptive of Na+ binding than mutations to other residues related to Na+ site III. The D928 (rat a1 numbering) mutations strongly diminished the cooperativity of Na+ binding. Moreover the p......H optimum of Na,K-ATPase activity was left-shifted, again with D928N being most disruptive. The reduced affinity for activating Na+ and for inhibitory protons, caused by D928N and D928A mutations, could be rescued by introduction of an additional mutation of a glutamate located far away from D928....

  10. Thermodiffusive behaviour of NaCl and KCl aqueous solutions a model for the Na-K pump

    International Nuclear Information System (INIS)

    Gaeta, F.S.; Mita, D.G.; Perna, G.; Scala, G.

    1975-01-01

    In NaCl and KCl aqueous nonisothermal solutions K + inverts its sense of migration within the physiological concentration range; Na + behaves similarly at much lower concentrations. These findings are discussed in relation to solute induced modifications of water structure and of their influence on thermal diffusion. A possible evolutionary model of a thermodiffusive mechanism for the sodium potassium pump is also suggested

  11. Evaluation of {sup 23}Na(n,2n){sup 22}Na reaction cross-sections

    Energy Technology Data Exchange (ETDEWEB)

    Manokhin, V N [Institute of Physics and Power Engineering, Obninsk (Russian Federation)

    1997-06-01

    Using available experimental data and (n,2n) excitation function systematics {sup 23}Na(n,2n){sup 22}Na reaction cross-sections were evaluated for energies ranging from the reaction threshold to 20 MeV. (author). 21 refs, 1 fig., 2 tabs.

  12. Endurance testing with Li/Na electrolyte

    Energy Technology Data Exchange (ETDEWEB)

    Ong, E.T.; Remick, R.J.; Sishtla, C.I. [Institute of Gas Technology, Des Plaines, IL (United States)

    1996-12-31

    The Institute of Gas Technology (IGT), under subcontract to M-C Power Corporation under DOE funding, has been operating bench-scale fuel cells to investigate the performance and endurance issues of the Li/Na electrolyte because it offers higher ionic conductivity, higher exchange current densities, lower vapor pressures, and lower cathode dissolution rates than the Li/K electrolyte. These cells have continued to show higher performance and lower decay rates than the Li/K cells since the publication of our two previous papers in 1994. In this paper, test results of two long-term 100-cm{sup 2} bench scale cells are discussed. One cell operated continuously at 160 mA/cm{sup 2} for 17,000 hours with reference gases (60H{sub 2}/20CO{sub 2}/20H{sub 2}O fuel at 75% utilization and 30CO{sub 2}/70 air oxidant humidified at room temperature at 50% utilization). The other cell operated at 160 mA/cm{sup 2} for 6900 hours at 3 atm with system gases (64H{sub 2}/16CO{sub 2}/20H{sub 2}O at 75% utilization and an M-C Power system-defined oxidant at 40% utilization). Both cells have shown the highest performance and longest endurance among IGT cells operated to date.

  13. Haveria uma antropologia infantil na modernidade?

    Directory of Open Access Journals (Sweden)

    José Carlos Souza Araujo

    2009-12-01

    Full Text Available Buscando situar uma conceituação de Modernidade, que se expressa paulatinamente a partir do século XIII, a criança e a infância são situadas como um fenômeno central na constituição da cultura ocidental a partir de então. O objeto deste trabalho é configurar alguns marcos filosóficos em torno da criança a partir do século XVI, representados pelas concepções de Martinho Lutero, Erasmo de Roterdão, Juan Luis Vives, Michel de Montaigne, John Locke, João Amós Comênio, Jean-Jacques Rousseau, Immanuel Kant, Johann Heinrich Pestalozzi, Friedrich W. A. Froebel, Johann Friedrich Herbart, William James, John Dewey e Antonio Gramsci. Evidentemente, tais pensadores revelam posições múltiplas, por vezes antagônicas, expressas através de antropologias assentadas no inatismo, no naturalismo, no deísmo, no empirismo, no cristianismo, no racionalismo, no idealismo, no materialismo histórico, entre outras. Entretanto, a criança é sempre situada em tais posicionamentos como um projeto inerente à cultura, constituindo-se a educação e a pedagogia como instrumentos para a sua formação.

  14. Lugares dos mortos na cristandade ocidental

    Directory of Open Access Journals (Sweden)

    Cláudia Rodrigues

    2013-01-01

    Full Text Available Resumo. Este artigo busca refletir sobre a forte associação entre morte e cristandade no Ocidente, buscando identificar os lugares dos mortos nos diferentes sistemas de cristandade. Propõe-se aqui a viabilidade de se pensar numa certa vinculação entre determinadas atitudes e representações diante da morte e do morrer e o sistema de cristandade vigente em determinados contextos históricos, entre fins da Antiguidade tardia e o século XX, mais especificamente em países nos quais a Igreja romana exerceu hegemonia sobre a sociedade. Procura argumentar que, enquanto predominou a modalidade “constantiniana”, os mortos faziam parte do cotidiano e a morte e foram instrumentos do projeto cristianizador. Quando este modelo de Cristandade recuou, diante da emergência da chamada “Cristandade pós-constantiniana” – na qual a Igreja não mais era braço do aparelho estatal –, os mortos tinham sido afastados da cidade dos vivos e a morte, ou melhor, o medo da morte não mais representava instrumento de pressão sobre a consciência do cidadão

  15. Energy stored in irradiated NaCl

    International Nuclear Information System (INIS)

    Lidiard, A.B.

    1979-01-01

    Recently reported measurements of the energy stored in heavily irradiated NaCl are reviewed in the light of recent understanding of radiation-damage processes in this material. It is shown that, in the ranges of temperatures and dose rates of these experiments, the F-centres produced by the irradiation are retained principally in the form of colloids: the stored energy is thus a direct measure of the number of F-centres retained in this form. Comparison of these results with the prediction of the recently proposed theory of colloid growth shows that the predictions of the dependence of colloid growth rates upon temperature and dose rate are qualitatively correct. The dependence of stored energy dose, however, appears to require the inclusion of a thermally activated back-reaction and possible modifications to the theory are briefly discussed. However, further experiments in this range of temperatures and dose rates are necessary for more quantitative tests of the theory. This reconsideration of the data does not alter the broad conclusion as to the relative insignificance of stored energy in a natural salt formation used as a radioactive waste repository, although more extensive measurements permitting a more exact test of theory would allow better predictions to be made for such applications. (author)

  16. Absorto na ação

    Directory of Open Access Journals (Sweden)

    Michael Fried

    2010-07-01

    Full Text Available O filme Zidane, um retrato do século XXI, de Douglas Gordon e Philippe Parreno (2006 pertence à tradição de absorção que desempenhou um papel crucial na evolução da arte moderna. O autor explora a tensão entre absorção e teatralidade - central tanto para a pintura francesa do século XVIII como para a fotografia dos séculos XX e XXI - e tira conseqüências estéticas e filosóficas do filme que retrata, ao longo de todos os noventa minutos de uma partida de futebol, o meio-campista francês Zinedine Zidane.Zidane, a 21st Century Portrait, a film by Douglas Gordon and Philippe Perreno, belongs to the absorptive tradition that has played a central role in the evolution of modern art. The author explores the tension between absorption and theatricality - crucial to 18th century French art as well as to 20th and 21th century photography - and draws aesthetic and philosophical consequences of this film that depicts, throughout all the 90 minutes of a soccer match, the French midfielder Zinedine Zidane.

  17. A Música Tradicional Madeirense na Transitoriedade

    Directory of Open Access Journals (Sweden)

    Rodolfo Cró

    2011-09-01

    Full Text Available O presente artigo procura expor, de uma forma sucinta, um conjunto de temáticas pertinentes ao contexto da música tradicional madeirense no atual panorama. Tendo como pano de fundo todas as transformações nos campos sociais, económicos e culturais, a contemporaneidade musical equaciona uma nova atitude, ou seja, uma necessidade reflexiva e crítica, face a um conjunto de elementos pluridimensionais. Contudo, a discussão em torno da globalização 1, ou seja “[…] o mundo como «aldeia global» […]” (Appadurai, 1996: 45 e da regionalização 2, ou seja, os “[…] particularismos ou culturas locais […]” (Featherstone, 2001: 84, em termos musicais, terá dese revestir numa proporção de dois conceitos, em que uma cultura conservadora dará lugar a uma cultura híbrida, no sentidoda modernidade. Tendo em conta que a evolução em princípio só se faz com programas culturais de renovação, experimentação e crítica (Canclini, 1992, é neste contexto que surgem as novas tecnologias; em concreto o software musical na sala de aula. Neste sentido, este artigo vem propor uma reflexão e um debate à luz de uma perspetiva cultural.

  18. Status for 2015, CERN NA63

    CERN Document Server

    Mikkelsen, RE; Wistisen, T

    2015-01-01

    We summarize the status for the CERN NA63 collaboration, where in 2015 we have had two runs at the CERN SPS, beamline H4: One with Ar ions at various energies around 75 GeV per nucleon, and one with electrons/positrons of 10-20 GeV. We previously refined and updated our theoretical analyses of bremsstrahlung and delta-electron emission from heavy, and medium-heavy, ultrarelativistic nuclei \\cite{Mikk15}. We thus concluded that - although not quite as interesting as for Pb projectiles - projectiles of Ar and/or Xe were suitable for the investigation, and for establishing the method to eventually measure the charge distribution of short-lived ($ct\\gtrsim3$m) fragments \\cite{Mikk14}. However, as the preliminary data analysis shows, the signal - which requires an intact projectile - is about three orders of magnitude lower than the background, stemming from photon emission (possibly originating from $\\pi^0$'s) in coincidence with projectiles that most likely are not intact after the collision. With the presently ...

  19. Artesanato na terceira idade: um estudo na cidade de Sinop no ano de 2011

    Directory of Open Access Journals (Sweden)

    Rosane Marlene Weber

    2015-04-01

    Full Text Available Essa pesquisa tem como objetivo mostrar a importância do artesanato na Terceira Idade como atividade educacional e de autonomia para os idosos. Por existir uma preocupação com a qualidade de vida da Terceira Idade e sua autonomia, nesta fase que muitos acabam ficando dependentes dos membros da família, espera-se encontrar através da arte uma motivação e uma forma de demonstrar a autoria por meio do fazer, criar e recriar com o artesanato. Aprender e ensinar são um processo contínuo na vida do ser humano, independente da idade, para Paulo Freire precisamos ter consciência de que somos inacabados, e sendo conscientes de nossa inconclusão, devemos viver num permanente movimento de busca. Essa é uma das causas pelas quais será pesquisada a prática formativa/educacional por meio do artesanato na Terceira Idade. Os motivos que levaram a escolha desta pesquisa com o artesanato na Terceira Idade é o fato de ter vivido uma experiência de trabalho na ala geriátrica de um hospital. Já o artesanato é a arte que fascina, e acreditamos que sempre há tempo para recomeçar, para descobrir algo que possa trazer qualidade para nossa vida. Devido ao crescimento cada vez maior da expectativa de vida em nosso país, cria-se uma preocupação com a qualidade de vida das pessoas da Terceira Idade. Em relação aos aspectos educacionais e culturais, esta pesquisa deseja compreender como o artesanato pode trazer motivação para as pessoas da Terceira Idade como forma de autoria e autonomia, nesta fase da vida, na cidade de Sinop, e quais os motivos que os levam a realizar esse tipo de atividade. Para investigação teórica desta pesquisa do Artesanato na Terceira Idade: um estudo na cidade de Sinop em 2011 usaremos bibliografia de vários autores, mas em especial os que dedicam seus estudos a esta faixa etária, como a coleção de Vivaidade, que tem como organizadora principal Anita Liberalesso Neri. Os autores desta coleção nos trazem a reflex

  20. Synthesis of Ag or Pt Nanoparticles by Hydrolysis of Either Ag2Na or PtNa

    Directory of Open Access Journals (Sweden)

    Huabin Wang

    2008-01-01

    Full Text Available Ag and Pt nanoparticles have successfully been synthesized by hydrolysis of either Ag2Na or PtNa at room temperature. The oxidation of sodium in the Pt-Na pellets was much faster than that in the Ag-Na pellets since Pt is a catalyst for H2O formation reaction from hydrogen and oxygen at room temperature. The hydrolysis byproduct, NaOH, has a high solubility and easily is removed. This method offers a simple method of preparing transition metal nanoparticles. The Ag and Pt nanoparticles prepared by this method were crystalline in nature, and spherical in shape with a mean size of around 10 nm.

  1. Characterization and antibacterial activity of silver exchanged regenerated NaY zeolite from surfactant-modified NaY zeolite

    Energy Technology Data Exchange (ETDEWEB)

    Salim, Mashitah Mad; Malek, Nik Ahmad Nizam Nik, E-mail: niknizam@fbb.utm.my

    2016-02-01

    The antibacterial activity of regenerated NaY zeolite (thermal treatment from cetyltrimethyl ammonium bromide (CTAB)-modified NaY zeolite and pretreatment with Na ions) loaded with silver ions were examined using the broth dilution minimum inhibitory concentration (MIC) method against Escherichia coli (E. coli ATCC 11229) and Staphylococcus aureus (S. aureus ATCC 6538). X-ray diffraction (XRD), attenuated total reflectance–Fourier transform infrared (ATR–FTIR) spectroscopy, field emission scanning electron microscopy (FESEM), energy dispersive X-ray (EDX) and chemical elemental analyses were used to characterize the regenerated NaY and AgY zeolites. The XRD patterns indicated that the calcination and addition of silver ions on regenerated NaY zeolite did not affect the structure of the regenerated NaY zeolite as the characteristic peaks of the NaY zeolite were retained, and no new peaks were observed. The regenerated AgY zeolite showed good antibacterial activity against both bacteria strains in distilled water, and the antibacterial activity of the samples increased with increasing Ag loaded on the regenerated AgY zeolite; the regenerated AgY zeolite was more effective against E. coli than S. aureus. However, the antibacterial activity of the regenerated AgY was not effective in saline solution for both bacteria. The study showed that CTAB-modified NaY zeolite materials could be regenerated to NaY zeolite using thermal treatment (550 °C, 5 h) and this material has excellent performance as an antibacterial agent after silver ions loading. - Highlights: • Thermal treatment was used to regenerate surfactant modified zeolite. • The regenerated NaY zeolite formed was added with different silver loadings. • Regenerated AgY zeolite was tested for antibacterial activity on E. coli and S. aureus. • The antibacterial activity increased with increased of the amount of silver loadings. • The zeolite structure did not change with thermal and modification

  2. Characterization and antibacterial activity of silver exchanged regenerated NaY zeolite from surfactant-modified NaY zeolite

    International Nuclear Information System (INIS)

    Salim, Mashitah Mad; Malek, Nik Ahmad Nizam Nik

    2016-01-01

    The antibacterial activity of regenerated NaY zeolite (thermal treatment from cetyltrimethyl ammonium bromide (CTAB)-modified NaY zeolite and pretreatment with Na ions) loaded with silver ions were examined using the broth dilution minimum inhibitory concentration (MIC) method against Escherichia coli (E. coli ATCC 11229) and Staphylococcus aureus (S. aureus ATCC 6538). X-ray diffraction (XRD), attenuated total reflectance–Fourier transform infrared (ATR–FTIR) spectroscopy, field emission scanning electron microscopy (FESEM), energy dispersive X-ray (EDX) and chemical elemental analyses were used to characterize the regenerated NaY and AgY zeolites. The XRD patterns indicated that the calcination and addition of silver ions on regenerated NaY zeolite did not affect the structure of the regenerated NaY zeolite as the characteristic peaks of the NaY zeolite were retained, and no new peaks were observed. The regenerated AgY zeolite showed good antibacterial activity against both bacteria strains in distilled water, and the antibacterial activity of the samples increased with increasing Ag loaded on the regenerated AgY zeolite; the regenerated AgY zeolite was more effective against E. coli than S. aureus. However, the antibacterial activity of the regenerated AgY was not effective in saline solution for both bacteria. The study showed that CTAB-modified NaY zeolite materials could be regenerated to NaY zeolite using thermal treatment (550 °C, 5 h) and this material has excellent performance as an antibacterial agent after silver ions loading. - Highlights: • Thermal treatment was used to regenerate surfactant modified zeolite. • The regenerated NaY zeolite formed was added with different silver loadings. • Regenerated AgY zeolite was tested for antibacterial activity on E. coli and S. aureus. • The antibacterial activity increased with increased of the amount of silver loadings. • The zeolite structure did not change with thermal and modification

  3. Rigidification of the autolysis loop enhances Na(+) binding to thrombin.

    Science.gov (United States)

    Pozzi, Nicola; Chen, Raymond; Chen, Zhiwei; Bah, Alaji; Di Cera, Enrico

    2011-11-01

    Binding of Na(+) to thrombin ensures high activity toward physiological substrates and optimizes the procoagulant and prothrombotic roles of the enzyme in vivo. Under physiological conditions of pH and temperature, the binding affinity of Na(+) is weak due to large heat capacity and enthalpy changes associated with binding, and the K(d)=80 mM ensures only 64% saturation of the site at the concentration of Na(+) in the blood (140 mM). Residues controlling Na(+) binding and activation have been identified. Yet, attempts to improve the interaction of Na(+) with thrombin and possibly increase catalytic activity under physiological conditions have so far been unsuccessful. Here we report how replacement of the flexible autolysis loop of human thrombin with the homologous rigid domain of the murine enzyme results in a drastic (up to 10-fold) increase in Na(+) affinity and a significant improvement in the catalytic activity of the enzyme. Rigidification of the autolysis loop abolishes the heat capacity change associated with Na(+) binding observed in the wild-type and also increases the stability of thrombin. These findings have general relevance to protein engineering studies of clotting proteases and trypsin-like enzymes. Copyright © 2011 Elsevier B.V. All rights reserved.

  4. Rigidification of the autolysis loop enhances Na+ binding to thrombin

    Science.gov (United States)

    Pozzi, Nicola; Chen, Raymond; Chen, Zhiwei; Bah, Alaji; Di Cera, Enrico

    2011-01-01

    Binding of Na+ to thrombin ensures high activity toward physiological substrates and optimizes the procoagulant and prothrombotic roles of the enzyme in vivo. Under physiological conditions of pH and temperature, the binding affinity of Na+ is weak due to large heat capacity and enthalpy changes associated with binding, and the Kd=80 mM ensures only 64% saturation of the site at the concentration of Na+ in the blood (140 mM). Residues controlling Na+ binding and activation have been identified. Yet, attempts to improve the interaction of Na+ with thrombin and possibly increase catalytic activity under physiological conditions have so far been unsuccessful. Here we report how replacement of the flexible autolysis loop of human thrombin with the homologous rigid domain of the murine enzyme results in a drastic (up to 10-fold) increase in Na+ affinity and a significant improvement in the catalytic activity of the enzyme. Rigidification of the autolysis loop abolishes the heat capacity change associated with Na+ binding observed in the wild-type and also increases the stability of thrombin. These findings have general relevance to protein engineering studies of clotting proteases and trypsin-like enzymes. PMID:21536369

  5. Hormonal regulation of Na -K -ATPase in cultured epithelial cells

    Energy Technology Data Exchange (ETDEWEB)

    Johnson, J.P.; Jones, D.; Wiesmann, W.P.

    1986-08-01

    Aldosterone and insulin stimulate Na transport through mechanisms involving protein synthesis. Na -K -ATPase has been implicated in the action of both hormones. The authors examined the effect of aldosterone and insulin on Na -K -ATPase in epithelial cells in culture derived from toad urinary bladder (TB6C) and toad kidney (A6). Aldosterone, but not insulin, increases short-circuit current (I/sub sc/) in TB6C cells. Aldosterone increases Na -K -(TSP)ATPase activity after 18 h of incubation, but no effect can be seen at 3 and 6 h. Amiloride, which inhibits aldosterone-induced increases in I/sub sc/, has no effect on either basal or aldosterone stimulated enzyme activity. Both aldosterone and insulin increase I/sub sc/ in A6 cells and when added together are synergistic. Aldosterone stimulates enzyme activity in A6 cells, but insulin alone has no effect. However, aldosterone and insulin together stimulate enzyme activity more than aldosterone alone. It appears that stimulation of Na -K -ATPase activity is involved in aldosterone action in both cell lines but does not appear to be due to increased Na entry, since enhanced enzyme activity is not inhibited by amiloride. In contrast, insulin alone has no direct effect on Na -K -ATPase, although the increased enzyme activity following both agents in combination may explain their synergism on I/sub sc/.

  6. NaIrO3-A pentavalent post-perovskite

    International Nuclear Information System (INIS)

    Bremholm, M.; Dutton, S.E.; Stephens, P.W.; Cava, R.J.

    2011-01-01

    Sodium iridium (V) oxide, NaIrO 3, was synthesized by a high pressure solid state method and recovered to ambient conditions. It is found to be isostructural with CaIrO 3 , the much-studied structural analog of the high-pressure post-perovskite phase of MgSiO 3 . Among the oxide post-perovskites, NaIrO 3 is the first example with a pentavalent cation. The structure consists of layers of corner- and edge-sharing IrO 6 octahedra separated by layers of NaO 8 bicapped trigonal prisms. NaIrO 3 shows no magnetic ordering and resistivity measurements show non-metallic behavior. The crystal structure, electrical and magnetic properties are discussed and compared to known post-perovskites and pentavalent perovskite metal oxides. -- Graphical abstract: Sodium iridium(V) oxide, NaIrO 3 , synthesized by a high pressure solid state method and recovered to ambient conditions is found to crystallize as the post-perovskite structure and is the first example of a pentavalent ABO 3 post-perovskite. Research highlights: → NaIrO 3 post-perovskite stabilized by pressure. → First example of a pentavalent oxide post-perovskite. → Non-metallic and non-magnetic behavior of NaIrO 3 .

  7. As valsas na Europa e na América do Sul

    OpenAIRE

    Almeida, Hélder António Moreira de

    2014-01-01

    Dissertação apresentado à Escola Superior de Artes Aplicadas do Instituto Politécnico de Castelo Branco para cumprimento dos requisitos necessários à obtenção do grau de Mestre em Performance. O objetivo deste trabalho é mostrar a história da valsa, a sua origem e influência de países da Europa Ocidental para a Europa do Sul como também a sua exportação Transatlântica para a América do sul. Pretendemos assim, mostrar o interesse destes compositores, na escrita desta forma mu...

  8. Search for dark photons in $\\pi^0$ decays at NA48 and NA62

    CERN Document Server

    Gonnella, Francesco

    2016-01-01

    The NA48/2 experiment at CERN collected, between 2003 and 2004, $1.69 \\times 10^{7}$ fully reconstructed $\\pi^{0} \\to \\gamma e^{+}e^{-}$ in the kinematic range $m_{ee}$ > 10 MeV/$c^{2}$, with a negligible background contamination. The sample is analysed to search for the presence of dark photons (${A}'$) via the decay chain $\\pi^{0} \\to \\gamma{A}', {A}' \\to e^{+}e^{-}$. No signal has been observed, and the exclusion limits on space of the dark photon mass $m_{{A}'}$ and the mixing parameter $e^{2}$ are reported.

  9. Electron scattering in graphene with adsorbed NaCl nanoparticles

    Energy Technology Data Exchange (ETDEWEB)

    Drabińska, Aneta, E-mail: Aneta.Drabinska@fuw.edu.pl; Kaźmierczak, Piotr; Bożek, Rafał; Karpierz, Ewelina; Wysmołek, Andrzej; Kamińska, Maria [Faculty of Physics, University of Warsaw, Pasteura 5, 02-093 Warsaw (Poland); Wołoś, Agnieszka [Faculty of Physics, University of Warsaw, Pasteura 5, 02-093 Warsaw (Poland); Institute of Physics, Polish Academy of Sciences, Al. Lotników 32/46, 02-668 Warsaw (Poland); Pasternak, Iwona; Strupiński, Włodek [Institute of Electronic Materials Technology, Wólczyńska 133, 01-919 Warsaw (Poland); Krajewska, Aleksandra [Institute of Electronic Materials Technology, Wólczyńska 133, 01-919 Warsaw (Poland); Institute of Optoelectronics, Military University of Technology, Kaliskiego 2, 00-908 Warsaw (Poland)

    2015-01-07

    In this work, the results of contactless magnetoconductance and Raman spectroscopy measurements performed for a graphene sample after its immersion in NaCl solution were presented. The properties of the immersed sample were compared with those of a non-immersed reference sample. Atomic force microscopy and electron spin resonance experiments confirmed the deposition of NaCl nanoparticles on the graphene surface. A weak localization signal observed using contactless magnetoconductance showed the reduction of the coherence length after NaCl treatment of graphene. Temperature dependence of the coherence length indicated a change from ballistic to diffusive regime in electron transport after NaCl treatment. The main inelastic scattering process was of the electron-electron type but the major reason for the reduction of the coherence length at low temperatures was additional, temperature independent, inelastic scattering. We associate it with spin flip scattering, caused by NaCl nanoparticles present on the graphene surface. Raman spectroscopy showed an increase in the D and D′ bands intensities for graphene after its immersion in NaCl solution. An analysis of the D, D′, and G bands intensities proved that this additional scattering is related to the decoration of vacancies and grain boundaries with NaCl nanoparticles, as well as generation of new on-site defects as a result of the decoration of the graphene surface with NaCl nanoparticles. The observed energy shifts of 2D and G bands indicated that NaCl deposition on the graphene surface did not change carrier concentration, but reduced compressive biaxial strain in the graphene layer.

  10. Electron scattering in graphene with adsorbed NaCl nanoparticles

    International Nuclear Information System (INIS)

    Drabińska, Aneta; Kaźmierczak, Piotr; Bożek, Rafał; Karpierz, Ewelina; Wysmołek, Andrzej; Kamińska, Maria; Wołoś, Agnieszka; Pasternak, Iwona; Strupiński, Włodek; Krajewska, Aleksandra

    2015-01-01

    In this work, the results of contactless magnetoconductance and Raman spectroscopy measurements performed for a graphene sample after its immersion in NaCl solution were presented. The properties of the immersed sample were compared with those of a non-immersed reference sample. Atomic force microscopy and electron spin resonance experiments confirmed the deposition of NaCl nanoparticles on the graphene surface. A weak localization signal observed using contactless magnetoconductance showed the reduction of the coherence length after NaCl treatment of graphene. Temperature dependence of the coherence length indicated a change from ballistic to diffusive regime in electron transport after NaCl treatment. The main inelastic scattering process was of the electron-electron type but the major reason for the reduction of the coherence length at low temperatures was additional, temperature independent, inelastic scattering. We associate it with spin flip scattering, caused by NaCl nanoparticles present on the graphene surface. Raman spectroscopy showed an increase in the D and D′ bands intensities for graphene after its immersion in NaCl solution. An analysis of the D, D′, and G bands intensities proved that this additional scattering is related to the decoration of vacancies and grain boundaries with NaCl nanoparticles, as well as generation of new on-site defects as a result of the decoration of the graphene surface with NaCl nanoparticles. The observed energy shifts of 2D and G bands indicated that NaCl deposition on the graphene surface did not change carrier concentration, but reduced compressive biaxial strain in the graphene layer

  11. Effect of chloride substitution on the order–disorder transition in NaBH4 and Na11BD4

    International Nuclear Information System (INIS)

    Olsen, Jørn Eirik; Karen, Pavel; Sørby, Magnus H.; Hauback, Bjørn C.

    2014-01-01

    Graphical abstract: Interactions that order the BD 4 - tetrahedra below the order–disorder transition became increasingly frustrated by the solute in the Na( 11 BD 4 ) 1−x Cl x solid solutions, and the order disappears at x = 0.158. Highlights: • The order–disorder transition temperature for Na(BH 4 ) 1−x Cl x and Na( 11 BD 4 ) 1−x Cl x is highly dependent on the Cl-content, x. • The transition is characterized by DSC for Na( 11 BD 4 ) 1−x Cl x for x = 0, 0.10 and 0.15. • No transition is observed for x ⩾ 0.20 on cooling to 8 K. • The crystal structures are reported for Na 11 BD 4 at room temperature and 8 K and Na( 11 BD 4 ) 1−x Cl x (x = 0.10, 0.15, 0.20 and 0.25) at 8 K from powder neutron diffraction. -- Abstract: Phase transition associated with anion disordering over two orientations in Na 11 BD 4 (NaBH 4 ) and its solid solutions with NaCl, Na( 11 BD 4 ) 1−x Cl x , is investigated with powder diffraction (neutron and synchrotron radiation), differential scanning calorimetry and Raman spectroscopy. Upon heating, the transition temperature extrapolated to zero rate of heating is 192.2 K for Na 11 BD 4 , ΔS = 4.41 J/mol K, hysteresis 1.7 K and the volume increase 0.43%. Thermal parameters of the transition in Na( 11 BD 4 ) 1−x Cl x follow a colligative-property model of an ideal solution, with x = 0.158(1) as the critical concentration at which the ordering interactions and the transition itself are eliminated. On approaching this limit, the tetragonal distortion of the ordered structure decreases somewhat towards the cubic average, and this is associated with a partial disorder of the tetrahedral anions seen by diffraction methods. In fact, a 3% disorder is already present in the pure solvent of the solid solution (Na 11 BD 4 ) at 8 K

  12. Na+/H+ and Na+/NH4+ exchange activities of zebrafish NHE3b expressed in Xenopus oocytes

    Science.gov (United States)

    Ito, Yusuke; Kato, Akira; Hirata, Taku; Hirose, Shigehisa

    2014-01-01

    Zebrafish Na+/H+ exchanger 3b (zNHE3b) is highly expressed in the apical membrane of ionocytes where Na+ is absorbed from ion-poor fresh water against a concentration gradient. Much in vivo data indicated that zNHE3b is involved in Na+ absorption but not leakage. However, zNHE3b-mediated Na+ absorption has not been thermodynamically explained, and zNHE3b activity has not been measured. To address this issue, we overexpressed zNHE3b in Xenopus oocytes and characterized its activity by electrophysiology. Exposure of zNHE3b oocytes to Na+-free media resulted in significant decrease in intracellular pH (pHi) and intracellular Na+ activity (aNai). aNai increased significantly when the cytoplasm was acidified by media containing CO2-HCO3− or butyrate. Activity of zNHE3b was inhibited by amiloride or 5-ethylisopropyl amiloride (EIPA). Although the activity was accompanied by a large hyperpolarization of ∼50 mV, voltage-clamp experiments showed that Na+/H+ exchange activity of zNHE3b is electroneutral. Exposure of zNHE3b oocytes to medium containing NH3/NH4+ resulted in significant decreases in pHi and aNai and significant increase in intracellular NH4+ activity, indicating that zNHE3b mediates the Na+/NH4+ exchange. In low-Na+ (0.5 mM) media, zNHE3b oocytes maintained aNai of 1.3 mM, and Na+-influx was observed when pHi was decreased by media containing CO2-HCO3− or butyrate. These results provide thermodynamic evidence that zNHE3b mediates Na+ absorption from ion-poor fresh water by its Na+/H+ and Na+/NH4+ exchange activities. PMID:24401990

  13. Vojnici, odlikovanja i vojno znakovlje na nadgrobnim spomenicima iz Viminacija

    OpenAIRE

    Milovanović, Bebina

    2014-01-01

    Vojnici, odlikovanja i vojna obilježja na nadgrobnim spomenicima iz Viminacija poznati su sa osam stela i jednog sarkofaga. Cijela figura vojnika prikazana na jednoj steli predstavlja osobu višeg ranga. Iz natpisa saznajemo da je spomenik napravljen u čast Gaja Kornelija Rufa, dekuriona (vijećnik) i augura (svećenik koji je imao zadatak protumačiti volju bogova promatrajući let i ponašanje ptica) iz Viminacija.Vojnik prikazan na sarkofagu je nižeg ranga. Vojna odlikovanja su prikazana u oblik...

  14. VPLIV OPTIMIZACIJE NABAVNEGA PROCESA NA USPEŠNOST NABAVNEGA MANAGEMENTA

    OpenAIRE

    Štraus, Nataša

    2015-01-01

    Vloga nabavne funkcije se je od njenih začetkov pa do danes močno spremenila. V današnjem poslovnem okolju nabava ni več le podporna funkcija, ampak ima pomembno strateško vlogo v podjetju. Odgovorna je za nemoteno oskrbo materialov in storitev, upravljanje zalog, odnose z dobavitelji, za etično in družbeno odgovorno ravnanje podjetja. Tesno je povezana z logistiko in njenimi strategijami. Pomembno vpliva na stroške vhodnih materialov, na konkurenčnost podjetja in posledično tudi na dobiček ...

  15. O outro na relação

    Directory of Open Access Journals (Sweden)

    Reinoldo Marquezan

    2012-03-01

    Full Text Available O texto aborda as contribuições de Meirieu em relação ao outro que se estabelece na relação pedagógica e de Maturana que refere o outro como legítimo outro da convivência. Aponta ser necessário estabelecer o outro na relação como legítimo outro para a consecução do ato pedagógica.Palavras-chave: O Outro na Relação. Relação Pedagógica.

  16. Negativen vpliv konkurence na dejavnost zasebnega varovanja v Republiki Sloveniji

    OpenAIRE

    Kolar, Mojca

    2018-01-01

    Po osamosvojitvi Slovenije se je na slovenskem trgu začela intenzivno razvijati tudi dejavnost zasebnega varovanja in število varnostnih služb je začelo strmo naraščati. Močna konkurenca med njimi je z leti prinesla v dejavnost varovanja veliko negativnih posledic. Ena izmed teh so tudi plače varnostnega osebja, ki so danes daleč pod slovenskim povprečjem. Toda za sistemom plač zaposlenih stoji plačni sistem storitev na trgu varovanja. Magistrska naloga obravnava problematiko neobičajno ...

  17. SPLETNA APLIKACIJA ZA PREVERJANJE NASTAVITEV ZASEBNOSTI NA FACEBOOKU

    OpenAIRE

    Žolek, Matija

    2013-01-01

    Diplomsko delo obravnava problem zasebnosti na spletnem družbenem omrežju Facebook. Pravice do zasebnosti so vse bolj izpostavljene okolju, v katerem se nahajamo. Prav zaradi spletnih družbenih omrežij, kot je npr. Facebook, postaja vprašanje nadzora nad našo zasebnostjo in uporabo naših zasebnih podatkov tako zelo aktualna tematika. Facebook, kot vodilni med spletnimi družbenimi omrežji (Mba, 2013), vzbuja veliko vprašanj glede varnosti osebnih podatkov uporabnika. Naredili smo aplikacijo za...

  18. Razumevanje trojne narave kemijske vezi na submikroskopski ravni

    OpenAIRE

    Klun, Tina

    2017-01-01

    Magistrsko delo celostno obravnava trojno naravo pojma kemijska vez s poudarkom na submikroskopski ravni. S pojmom kemijska vez se učenci v Sloveniji srečajo v osmem razredu osnovne šole v tematskem sklopu povezovanje delcev/gradnikov. Zaradi abstraktnosti pojma kemijska vez je pomembno, da se pri učencih spodbuja učenje na makroskopski, submikroskopski in simbolni ravni, saj je tak način dela ključnega pomena za oblikovanje ustreznega mentalnega modela o kemijski vezi pri učencih. Pri gradnj...

  19. Utjecaj visokog hidrostatskog tlaka na kemijski sastav vina

    OpenAIRE

    Gelo, Klara

    2017-01-01

    U ovom radu ispitivan je utjecaj obrade visokim hidrostatskim tlakom na kemijski sastav crnog i bijelog vina. Određivani parametri su količina ukupnih polifenola, antocijana, tanina, boje, sumpora te kisika. Uzorci bijelog i crnog vina tretirani su visokim hidrostatskim tlakom od 200, 400 i 600 MPa u trajanju od 5, 15 i 25 minuta. Ispitivanjem utjecaja visokog hidrostatskog tlaka na kemijski sastav crnog i bijelog vina utvrđeno je da nema značajnije promjene u navedenim svojstvima. Na temelju...

  20. Personalidades vocacionais e processos de carreira na vida adulta

    OpenAIRE

    Magalhães, Mauro de Oliveira; Gomes, William B.

    2007-01-01

    Esta pesquisa abordou a relação entre interesses vocacionais e os processos de comprometimento e entrincheiramento na carreira em diferentes fases da vida. Uma amostra de 733 profissionais (415 homens e 318 mulheres) respondeu a medidas de comprometimento e de entrincheiramento na carreira. Os sujeitos foram categorizados de acordo com o interesse vocacional predominante na tipologia de Holland. As análises revelaram interação entre estágio de vida e personalidade vocacional para os escores d...

  1. ANALIZA UPORABNIŠKIH VMESNIKOV NA MOBILNIH NAPRAVAH

    OpenAIRE

    Bohak, Gregor

    2012-01-01

    V diplomskem delu smo predstavili pravila in smernice oblikovanja uporabniških vmesnikov na mobilnih napravah. Omejili smo se na platforme Google Android, Nokia Symbian, Nokia MeeGo, Apple iOS ter Microsoft Windows Phone 7. Za vsako izmed platform smo predstavili splošen model uporabniškega vmesnika, splošen model uporabniškega vmesnika aplikacije, navigacijske vzorce ter gradnike. Vse skupaj tudi smo obogatili z veliko grafičnega materiala. V drugem delu smo na podlagi pridobljenega znanja p...

  2. Direct extraction of a Na- beam from a sodium plasma

    International Nuclear Information System (INIS)

    Sasao, Namiko; Fujita, Junji; Yamaoka, Hitoshi; Wada, Motoi.

    1990-07-01

    Negative sodium ions (Na - ) were extracted from a small multi-cusp ion source. A steady state sodium plasma was produced by primary electrons in a sodium gas evaporating from a metal sample placed in the discharge chamber. The Na - current density of 1.5 μA/cm 2 was obtained from a single aperture of 1.5 mm diameter at relatively low discharge power of about 0.4 W and filament power of 50 W. Extraction characteristics were studied by changing the plasma electrode bias. The extracted Na - current showed dependence on the bias voltage similar to that of H - or Li - volume production. (author)

  3. Polimorfismo na produção de medicamentos

    Directory of Open Access Journals (Sweden)

    Gabriel Lima Barros de Araujo

    2012-01-01

    Full Text Available O polimorfismo pode ocasionar desvios de qualidade durante o processo produtivo e influenciar o desempenho dos medicamentos. Por isso, o entendimento do fenômeno e suas implicações abre um campo amplo de possibilidades a serem exploradas na área farmacêutica, incluindo o surgimento de novos paradigmas e ferramentas na garantia da qualidade de medicamentos. Este trabalho apresenta uma introdução aos aspectos básicos do fenômeno do polimorfismo e suas implicações na produção e controle de medicamentos, com ênfase no polimorfismo dos fármacos.

  4. VPLIV VAN DER WAALSOVIH SIL NA TVORBO ASOCIIRANIH MOLEKUL

    OpenAIRE

    Kuster, Bernarda

    2014-01-01

    Namen diplomske naloge je preučiti vpliv van der Waalsovih sil na tvorbo asociiranih molekul. V ta namen smo izbrali površinsko aktivne snovi, ki imajo amfifilne lastnosti in vplivajo na povšinske in medfazne napetosti ter pri določeni koncentraciji, imenovani kritična micelna koncentracija (CMC), tvorijo molekulske skupke, ki jim pravimo micele. Kritično micelno koncentracijo smo določili trem površinsko aktivnim snovem: heksadeciltrimetilamonijevemu bromidu, tetradeciltrimetilamonijevemu b...

  5. Técnica intramuscular na gluteoplastia de aumento

    OpenAIRE

    Carvalho, Francisco de Assis Montenegro Cido; Alcântara, Fernando Soares de; Martins, Elmiro Heli; Kruse, Ricardo Lapa; Nogueira, Régis Pinheiro; Raad, Nidall de Sousa

    2012-01-01

    INTRODUÇÃO: Região glútea harmoniosa é considerada elemento essencial na composição da beleza corporal e expressão maior de feminilidade, suscitando o crescente interesse de homens e mulheres na melhoria estética dessa região. O objetivo deste estudo é demonstrar uma alternativa às técnicas já publicadas acerca da gluteoplastia de aumento, baseada na colocação da prótese intramuscular, utilizando de forma simplificada os limites da dissecção, tendo como referência as estruturas anatômicas fix...

  6. Fluorine-18 NaF PET imaging of child abuse

    Energy Technology Data Exchange (ETDEWEB)

    Drubach, Laura A. [Children' s Hospital Boston and Harvard Medical School, Department of Radiology, Division of Nuclear Medicine/PET, Boston, MA (United States); Sapp, Mark.V. [School of Osteopathic Medicine, Child Abuse Research Education and Services (CARES) Institute University of Medicine and Dentistry of New Jersey, New Jersey (United States); Laffin, Stephen [Children' s Hospital Boston, Department of Radiology, Division of Nuclear Medicine/PET, Boston, MA (United States); Kleinman, Paul K. [Children' s Hospital Boston and Harvard Medical School, Department of Radiology, Division of Musculoskeletal Imaging, Boston, MA (United States)

    2008-07-15

    We describe the use of {sup 18}F-NaF positron emission tomography (PET) whole-body imaging for the evaluation of skeletal trauma in a case of suspected child abuse. To our knowledge, 18F NaF PET has not been used in the past for the evaluation of child abuse. In our patient, this technique detected all sites of trauma shown by initial and follow-up skeletal surveys, including bilateral metaphyseal fractures of the proximal humeri. Fluorine-18 NaF PET has potential advantage over Tc-99m-labeled methylene diphosphonate (MDP) based upon superior image contrast and spatial resolution. (orig.)

  7. Fluorine-18 NaF PET imaging of child abuse

    International Nuclear Information System (INIS)

    Drubach, Laura A.; Sapp, Mark V.; Laffin, Stephen; Kleinman, Paul K.

    2008-01-01

    We describe the use of 18 F-NaF positron emission tomography (PET) whole-body imaging for the evaluation of skeletal trauma in a case of suspected child abuse. To our knowledge, 18F NaF PET has not been used in the past for the evaluation of child abuse. In our patient, this technique detected all sites of trauma shown by initial and follow-up skeletal surveys, including bilateral metaphyseal fractures of the proximal humeri. Fluorine-18 NaF PET has potential advantage over Tc-99m-labeled methylene diphosphonate (MDP) based upon superior image contrast and spatial resolution. (orig.)

  8. Epidemiologia da raiva humana na Guanabara

    Directory of Open Access Journals (Sweden)

    Alfredo R. Matta B. da Silva

    1971-08-01

    Full Text Available A raiva humana se mantém como problema de Saúde Pública, especialmente nas áreas urbanas, onde o cão atua como principal reservatório e fonte imediata de infecção. A deficiência de programas de controle de cães vadios, de imunização sistemática e de educação sanitária, contribui para a perpetuação da cadeia epidemiológioa. O presente estudo analisa todos os casos de raiva humana, observados em habitantes do Estado da Guanabara, no período 1965-1969, segundo as variáveis: idade, sexo, côr, variação estacional, período de incubação e de duração da fase clínica, fonte de infecção, local de mordedura e uso de vacina posterior à exposição. Os principais resultados foram: 1. A ravia na Guanabara, parece ser mais comum nos grupos etários mais jovens e nos homens. 2. Não se observou variação estacional. 3. O período de incubação mediano foi de 45 dias e de duração da fase clínica de 3 dias. 4. Ocorreu uma associação entre período de incubação menor e vacinação incompleta.

  9. Cidade-ciborgue: a cidade na cibercultura

    Directory of Open Access Journals (Sweden)

    André Lemos

    2008-11-01

    Full Text Available As cidades contemporâneas passam por transfigurações importantes com o advento das novas tecnologias da comunicação e informação e, embora toda cidade seja um artefato complexo composto por diversas redes materiais e espirituais (Saint Simon, podemos ver as atuais cidades como uma cidade-ciborgue. O objetivo deste artigo é descrever e analisar as principais transformações pelas quais passa o espaço urbano na atual cibercultura. Torna-se urgente compreender as transformações da cidade contemporânea em meio às novas tecnologias de base micro-eletrônica e de telecomunicações. Pretendemos aqui abordar a questão das cidades da cibercultura sob o prisma do que chamaremos "cidade-ciborgue". Palavras-chave cibercultura, cibercidade, cidade, comunicação Abstract Cities have been through major transformations due to information and communication technologies. Although every city is a complex artifact made of several material and spiritual networks (Saint Simon, we can view our modern cities as cyborg-cities. The aim of this paper is to describe and analyze some major changes in the urban space in terms of cyberculture. There is a need to understand the transformations of the contemporary city in face of the new technologies of telecommunications and microelectronics. We intend to approach the subject of cities and cyberculture from the point of view of what we are calling "the cyborg-city". Key words cyberculture, cybercity, city, communication

  10. A publicidade na perspectiva de Baudrillard

    Directory of Open Access Journals (Sweden)

    Maria Ogécia Drigo

    2009-09-01

    Full Text Available Resumo O propósito deste artigo é apresentar as idéias de Baudrillard sobre publicidade, tratadas na obra O sistema dos objetos. Assim, discutem-se os conceitos de arranjo e de ambiência que culminam no conceito de funcionalidade, os quais permitem apresentar as relações que se estabelecem entre os seres humanos, e entre eles e os objetos. Em seguida, aborda-se o papel da publicidade em meio a esses objetos/signos. Palavras-chave: Jean Baudrillard; comunicação; publicidade; funcionalidade; objetos/signos. Resumen El propósito de este artículo es presentar las ideas de Baudrillard sobre la publicidad, que constan en la obra El sistema de los objetos. Se discuten los conceptos de arreglo y de ambiencia que culminan en el concepto de funcionalidad, los cuales permiten presentar las relaciones que se establecen entre los seres humanos y entre ellos y los objetos. En seguida,se aborda el papel de la publicidad en medio de esos objetos/signos. Palabras-clave: Jean Baudrillard; comunicación; publicidad; funcionalidad; objetos/signos. Abstract This article intends to present Baudrillard’s ideas about advertising as considered in “Le système des objects”, his first book. The concepts of settlement, ambience and functionality are discussed. They make it possible to present the relations constructed among human beings and among humans and objects. We then discuss the role of advertising amongst these objects/signs. Keywords: Jean Baudrillard; communication; advertising; functionality; objects/signs.

  11. PRAVO NA PRISTUP SUDU EUROPSKE UNIJE

    Directory of Open Access Journals (Sweden)

    Katarina Knol Radoja

    2016-01-01

    Full Text Available Restriktivni pristup tumačenja pretpostavki dopuštenosti podnošenja tužbe za poništenje pred Sudom Europske unije kada su u pitanju fizičke i pravne osobe prije donošenja Lisabonskog ugovora bio je predmetom niza doktrinarnih kri- tika. Cilj je ovog rada analizirati praktični utjecaj novih pravila o dopuštenosti podnošenja tužbe u svjetlu interpretativnih rješenja koje je dao Sud. Konkret- no, analizirat će se imaju li temeljem novog članka 263. stavka 4. Ugovora o funkcioniranju Europske unije privatni podnositelji jednostavniji pristup Sudu Europske unije u usporedbi s onim prije izmjena iz Lisabonskog ugovora. Osim toga, analizirat će se i kompatibilnost navedenog članka s međunarodnim ob- vezama koje proizlaze iz Aarhuške konvencije o pristupu informacijama, sud- jelovanju javnosti u odlučivanju i pristupu pravosuđu u pitanjima okoliša, spo- razuma kojeg je i Europska unija stranka. Na kraju rada, dolazi se do zaključka da, unatoč postojanju određenog napret- ka u smislu olakšavanja fizičkim i pravnim osobama pristup sudu, tim će oso- bama izravni pristup, radi osporavanja nezakonitosti akata tijela i institucija Europske unije i dalje biti dostupan samo u ograničenim slučajevima.

  12. O Perfume ou o Ignorado na Cultura

    Directory of Open Access Journals (Sweden)

    Márcio Boaventura Jr.

    2011-05-01

    Full Text Available

    Resumo: A proposta do artigo é analisar o filme “Perfume, a história de um assassino” de Tom Tykwer sob o ponto de vista da psicanálise e da educação. Para tanto, buscamos debater o mal-estar na cultura, especialmente suas manifestações nas salas de aula, a partir dos diversos pontos do enredo em que podemos ilustrar o que Freud argumentou em sua tese sobre o tema.

     

    Resume: This article is intended to analyze Tom Tykwer's film Perfume: The Story of a Mur-derer (2006 under an educational and psychoanalytical perspective. Therefore we try to question cultural discontentment, mostly its manifestations in class, depicting the plot's many points of view to illustrate Freud thesis' arguing on the subject.

     

  13. Borehole sealing with highly compactd Na bentonite

    International Nuclear Information System (INIS)

    Pusch, R.

    1981-12-01

    This report describes the use of highly compacted Na bentonite for borehole plugging. Bentonites have an extremely low permeability and a low diffusivity, and a swelling ability which produces a nonleaching boundary between clay and rock if the initial bulk density of the bentonite is sufficiently high. The suggested technique, which is applicable to long vertical, and inclined, as well as horizontal boreholes, is based on the use of perforated copper pipes to insert elements of compacted bentonite. Such pipe segments are connected at the rock surface and successively inserted in the hole. When the hole is equipped, the clay takes up water spontaneously and swells through the perforation, and ultimately forms an almost completely homogenous clay core. It embeds the pipe which is left in the hole. Several tests were conducted in the laboratory and one field test was run in Stripa. They all showed that a gel soon fills the slot between the pipe and the confinement which had the form of metal pipes in the laboratory investigations. Subsequently, more clay migrates through the perforation and produces a stiff clay filling in the slot. The redistribution of minerals, leading ultimately to a high degree of homogeneity, can be described as a diffusion process. The rate of redistribution depends on the joint geometry and water flow pattern in the rock. In the rock with an average joint frequence of one per meter or higher, very good homogeneity and sealing ability of the clay are expected within a few months after the application of the plug. (author)

  14. Afferent loop syndrome - a case report; Sindrome da alca aferente - relato de um caso

    Energy Technology Data Exchange (ETDEWEB)

    Borges, Ana Karina Nascimento; Pinheiro, Marco Antonio Lopes; Galvao, Cristine Norwig [Fundacao Pio XII - Hospital do Cancer de Barretos, SP (Brazil)

    2000-02-01

    The afferent loop syndrome occurs in patients with previous gastric surgery for tumor, when there is anastomotic edema, use of inappropriate reconstruction technique for gastro jejunostomy or recurrent gastric cancer. Complaints such jaundice, intermittent abdominal distension associated with pain, and vomiting should be investigated in order to rule out this syndrome. (author)

  15. Sentido de Coherencia y Sindrome de Burnout en el personal sanitario de Urgencias

    OpenAIRE

    Vega Martínez, Maria del Carmen

    2013-01-01

    El Sentido de coherencia es un término que hace referencia a la capacidad del individuo par aver su entorno individual y el mundo que les rodea. El Síndrome de Burnout es un problema que afecta a los profesionales sanitarios cada vez, proporcionándoles síntomas como: fatiga, insomnio, cefaleas, deterioro de comunicación con pacientes / otros profesionales y hasta se puede llegar a poner en riesgo la salud del paciente atendido. Después del pase de cuestionarios de forma adecuada a 69 pro...

  16. Imaging in Cushing's syndrome; Imagem em sindrome de Cushing

    Energy Technology Data Exchange (ETDEWEB)

    Sahdev, Anju; Evanson, Jane [St. Bartholomew' s Hospital, London (United Kingdom). Dept. of Diagnostic Imaging; Reznek, Rodney H. [St. Bartholomew' s Hospital, London (United Kingdom). Institute of Cancer. Cancer Imaging; Grossman, Ashley B. [St. Bartholomew' s Hospital, London (United Kingdom). Dept. of Endocrinology]. E-mail: anju.sahdev@bartsandthelondon.nhs.uk

    2007-11-15

    Once the diagnosis of Cushing's syndrome (CS) has been established, the main step is to differentiate between ACTH dependent and independent disease. In adults, 80% of CS is due to ACTH-dependent causes and 20% due to adrenal causes. ACTH-secreting neoplasms cause ACTH-dependent CS. These are usually anterior pituitary microadenomas, which result in the classic Cushing's disease. Non-pituitary ectopic sources of ACTH, such as a small-cell lung carcinoma or carcinoid tumours, are the source of the remainder of ACTH-dependent disease. In the majority of patients presenting with clinical and biochemical evidence of CS, modern non-invasive imaging can accurately and efficiently provide the cause and the nature of the underlying pathology. Imaging is essential for determining the source of ACTH in ectopic ACTH production, locating the pituitary tumours and distinguishing adrenal adenomas, carcinomas and hyperplasias. In our chapter we review the adrenal appearances in ACTH-dependent and ACTH-independent CS. We also include a discussion on the use of MRI and CT for the detection and management of pituitary ACTH secreting adenomas. CT of the chest, abdomen and pelvis with intravenous injection of contrast medium is the most sensitive imaging modality for the identification of the ectopic ACTH source and detecting adrenal pathology. MRI is used for characterising adrenal adenomas, problem solving in difficult cases and for detecting ACTH-secreting pituitary adenomas. (author)

  17. Strategie di coping e sindrome da burnout nei Vigili del Fuoco

    Directory of Open Access Journals (Sweden)

    Alessandra Curtacci

    2017-03-01

    Full Text Available In the last decades, we have seen a rapid growth in the culture of prevention, safety and care for people involved in dramatic events. These calamites, both natural and human made, can have a profound effect on the mental stability of individuals and communities. These effects can have consequences on people, which may go on for days, months and even years during the recovery, rebuilding and re-establishment of an ordinary situation. Each event due to these circumstances is an emergency from a technical-practical and also human point of view. And that is because people are forced to fight in order to survive physically and emotionally in a state of dangerousness and dramatic force. During an emergency it is necessary to help people recognize normality in their own reactions, which are consequences of a situation out of ordinary. A greater focus on the emotional and cognitive component of the person involved is needed. Actually, this component proves to be very important both for the successful management of the situation - being involved in the prevention and preparation phases - and for its contribution to a mitigation of the effects of a specific event. It is widely known that during an emergency, interventions by psychologists trained to face various contexts (e.g., incidents, natural disasters and so on and able to cooperate with other professionals are needed. The aim is to promote in the people involved, both rescuers and victims, the capacity to cope with the situation, in the short term and in the long term.

  18. SINDROME DE INMUNODEFICIENCIA ADQUIRIDA. COMPROMISO DEL CORAZÓN Y DE LOS VASOS

    Directory of Open Access Journals (Sweden)

    Dr. Jorge Yovanovich S.

    2015-03-01

    Full Text Available Las complicaciones cardiovasculares del SIDA, son a menudo asintomáticas, aunque en ocasiones pueden constituir la causa directa de muerte. Puede comprometerse el pericardio, miocardio, endocardio y los vasos, ya sea como manifestación de la enfermedad de base o como resultado de la terapia antirretroviral y su efecto sobre los factores de riesgo, en el contexto de una patología que es actualmente de evolución crónica y con mejores expectativas de sobrevida gracias a las nuevas drogas empleadas para su control y tratamiento. El objetivo de este artículo es presentar una revisión de los aspectos más relevantes del SIDA que comprometen al corazón y los vasos.

  19. Giperkortitsizm i metabolicheskiy sindrom: slozhnosti differentsial'noy diagnostiki i lecheniya

    Directory of Open Access Journals (Sweden)

    L K Dzeranova

    2012-06-01

    Full Text Available Hypercortisolism is a severe endocrine disorder that leads to all types of metabolic disturbances. The most frequent symptom of hypercortisolism is a specific weight gain and body fat distribution - "cushingoid" obesity which clinically reflects the pathological changes in protein, carbohydrate and lipids metabolism. We provide a clinical case of a patient with Cushing's disease. This clinical case represents challenges in the differential diagnosis of this rare endocrine disorder and metabolic syndrome, and specific approach in further evaluation and treatment of Cushing's disease that requires all the latest technology in this field to be employed.

  20. Heterotaxy syndrome: a case report; Sindrome de heterotaxia: relato de caso

    Energy Technology Data Exchange (ETDEWEB)

    Carneiro, Daniel de Souza; Arantes, Jamil Hussein de; Souza, Gustavo Veloso de; Barreto, Aline Santos; Cardoso, Mychaell Luciano; Gontijo, Flavia, E-mail: danielmed124@gmail.com [Hospital Madre Tereza, Belo Horizonte, MG (Brazil)

    2013-05-15

    The present report describes the findings at chest computed tomography angiography of a 28-year-old female patient with heterotaxy syndrome. This syndrome consists of a variety of anomalies of position and morphology of thoracoabdominal organs which do not follow the situs solitus or situs inversus arrangement. Imaging studies play a fundamental role in the individualization of the approach to the patient. (author)

  1. [Pure gonad dysgenesia or Swyer sindrome. A case report having tumoral development: melanoma].

    Science.gov (United States)

    Russo, D; Blanco, M; Falke, G; Rocca Rivarola, M; Séller, R; Puigdevall, J C; Bergada, C

    2006-10-01

    A 14 year old girl having 10-days lumbar pain, polaquiuria and moderate pain to palpation is reported. Blood and urine analysis were normal. Abdominal ultrasound scan showed cavity free and solid, rounded, heterogeneous, intrapelvic mass compressing bladder and uterus. Magnetic resonance image was performed showing right gonad compromise with extensive liver and sacro-lumbar spine invasion. Tumoral markers were ruled out. During surgery, primary tumor mass localizad in the right gonad was completely excised. Melanotic peritoneal and hepatic disemination were observed. The patient had left streak gonad and infantile uterus (2 x 3 cm). As gonad dysgenesia was suspected, high resolution cromosomic study was performed and resulted in cariotype 46 XY. Microscopy of the resected gonad showed primary gonad melanoma. Chemotherapy was instituted with no tumor response and the patient died two month later.

  2. [Dissociation of antihypertensive and metabolic response to losartan and spironolactone in experimental rats with metabolic sindrome].

    Science.gov (United States)

    Machado, Hussen; Pinheiro, Helady Sanders; Terra, Marcella Martins; Guerra, Martha de Oliveira; de Paula, Rogerio Baumgratz; Peters, Vera Maria

    2012-01-01

    The treatment of arterial hypertension (AH) in patients with metabolic syndrome (MS) is a challenge, since non drug therapies are difficult to implement and optimal pharmacological treatment is not fully established. To assess the blockade of the rennin angiotensin aldosterone system (RAAS) in blood pressure (BP) in renal function and morphology in an experimental model of MS induced by high fat diet. Wistar rats were fed on high fat diet from the fourth week of life, for 20 weeks. The groups received Losartan or Spironolactone from the eighth week of life. We weekly evaluated the body weight and BP by tail plethysmography. At the end of the experiment oral glucose tolerance, lipid profile, creatinine clearance tests, and the direct measurement of BP were performed. A morphometric kidney analysis was performed. The administration of high-fat diet was associated with the development of MS, characterized by central fat accumulation, hypertension, hyperglycemia and hypertriglyceridemia. In this model there were no changes in renal histomorphometry. The blockade of angiotensin II (Ang II) receptor AT1 prevented the development of hypertension. The mineralocorticoid blockage did not have antihypertensive efficacy but was associated with reduction of abdominal fat. The dissociation of the antihypertensive response to the blockades of Ang II receptors and mineralocorticoid indicates the involvement of Ang II in the pathogenesis of hypertension associated with obesity. Reduction of central obesity with Spironolactone suggests the presence of mineralocorticoid adipogenic effect.

  3. Acute gastrointestinal bleeding following aortic valve replacement in a patient with Heyde's sindrome. Case report.

    Science.gov (United States)

    De Palma, G D; Salvatori, F; Masone, S; Simeoli, I; Rega, M; Celiento, M; Persico, G

    2007-09-01

    A 58-year old man was admitted to the hospital because of melena. He had a 1-year history of mechanical aortic valve replacement and coronary stent placement because of myocardial infarction and he was taking warfarin and clopidogrel. Esophagogastroduodenoscopy and colonoscopy were negative for bleeding. Capsule endoscopy showed bleeding diffuse angiodysplasia of the small bowel. The patient was treated with octreotide 20 mg, at monthly interval. After 25 months there had been no recurrence of gastrointestinal bleeding. The case suggests that mechanical valve replacement may not prevent gastrointestinal bleeding in Heyde syndrome and that octreotide treatment should be considered in these cases.

  4. Relaciones de la grasa visceral y de tronco con el sindrome metabólico

    OpenAIRE

    Fernández Vázquez, Rosalía Asunción

    2016-01-01

    La obesidad central es uno de los componentes que conforman el conjunto de factores del síndrome metabólico. La obesidad central se asocia a una gran incidencia de diabetes tipo 2, resistencia a la insulina, hipertensión arterial y particularmente a las enfermedades cardiovasculares. Las acciones metabólicas del tejido adiposo visceral son por sí solas un factor de riesgo independiente para una serie de alteraciones metabólicas. Objetivos: Los objetivos de la presente tesis han sido estudiar ...

  5. Pengaruh pemberian yogurt sinbiotik tepung pisang tanduk terhadap profil lipid tikus sindrom metabolik

    Directory of Open Access Journals (Sweden)

    Zana Fitriana Octavia

    2017-04-01

    Full Text Available Background: The metabolic syndrome, which is characterized by hyperglycemia, obesity, dyslipidemia, hypertension, prothrombic and proinflamatory state, is a risk factor for cardiovascular disease and diabetes mellitus. The synbiotic yogurt of tanduk banana (Musa paradisiaca fa. corniculata flour contains lactic acid bacteria, fructooligosaccarides, flavonoids, and vitamin C which all of them play role in improving the lipid profile. Objective: The aim of this study was to prove the effect of synbiotic yogurt of tanduk banana flour on lipid profile of metabolic syndrome rats. Method: This study was an true experimental with pre-post test  control group design. The subject of this study were 18 metabolic syndrome male Wistar rats divided into 3 groups,i.e control group (standart diet, intervention group I (standart diet and synbiotic yogurt of banana flour 0,009 ml/g weight/day, and intervention group II (standart diet and synbiotic yogurt of banana flour 0,018 ml/g weight/day. The intervention period was 2 weeks. Different test before and after intervention used paired t-test. The difference test between groups used One-Way ANOVA and Kruskal wallis. Results: The result showed that both of intervention group improved lipid profile significantly (p<0,05. The intervention group II showed more effective improvement of lipid profile significantly (p<0,05 than intervention group I. The intervention group II decreased triglycerides level 41,56%; total cholesterol level 41,39%; LDL-cholesterol level 57,5%; and increased HDL-cholesterol level 139,62%. Conclucion: The intervention of synbiotic yogurt of  tanduk banana flour can decrease triglyceride level, total cholesterol level, LDL-cholesterol level, and increase HDL-cholesterol level.

  6. Sindrome de la cintilla iliotibial: presentación de un caso clínico

    OpenAIRE

    Gómez Verde, Virginia

    2013-01-01

    Introducción: el síndrome de la cintilla iliotibial es un cuadro clínico relativamente frecuente en el ámbito deportivo, sobre todo en personas que participan en actividades físicas de resistencia, principalmente en corredores de fondo y ciclistas. Se caracteriza por dolor agudo en la cara externa de rodilla y se ha asociado con una flexoextensión repetitiva de rodilla en combinación con una banda iliotibial tensa Objetivo: aplicar un plan de intervención fisioterapéutico en...

  7. Osseous involvement in AIDS patients; Comprometimento osseo no paciente com sindrome da imunodeficiencia adquirida

    Energy Technology Data Exchange (ETDEWEB)

    Marchiori, Edson [Universidade Federal Fluminense, Niteroi, RJ (Brazil). Dept. de Radiologia]|[Universidade Federal, Rio de Janeiro, RJ (Brazil); Pereira, Abercio Arantes [Universidade Federal, Rio de Janeiro, RJ (Brazil). Faculdade de Medicina

    1995-07-01

    The radiological findings of eight patients with the acquired immunodeficiency syndrome (AIDS) who developed bone lesions were analyzed in conjunction with twelve similar published cases. Our series included three patients with lymphoma, two with bacillary angiomatosis, two with tuberculosis and one with staphylococcal osteomyelitis. All the lesions were lithic regardless of the etiology. Both in our cases and in those previously published bone repair was only seen in cases of bacillary angiomatosis treated with erythromycin. No pathognomonic findings were observed. However, the association of skin and bone lesions in immuno deficient patients should always bring the consideration of bacillary angiomatosis in the differential diagnosis. This is particularly relevant since this a condition amenable to treatment once correctly identified. The radiological findings in the lymphoma and tuberculosis patients have not been described previously. (author). 9 refs., 7 figs., 3 tabs.

  8. SINDROME DE APNEAS/HIPOPNEAS DURANTE EL SUEÑO EN EDAD PEDIÁTRICA

    Directory of Open Access Journals (Sweden)

    Navazo Eguía A

    2006-08-01

    Full Text Available SUMMARY:Sleep disordered breathing (SDB is a common condition in children. Sleep Apnea/Hypopnea syndrome (SAHS in children is a frequent sleep disorder, with a prevalence estimated to be 1 - 3% of all children. The most frequent cause of SAHS in children is the adenotonsillar hypertrophy. SAHS in children can result in severe complications if left untreated such as impaired physical growth, delayed development, poor school performance and in severe cases, hypertension and cor pulmonale, nevertheless, yet it is an under recognized condition. The gold standard diagnostic technique is the nocturnal polysomnography (PSG, guidelines for performing laboratory-based polysomnography in children have been established, the sleep laboratory should be a nonthreatening environment and personnel with pediatric training should record, score and interpret the study. The diagnostic criteria for SAHS in adults is not useful for diagnosis of SAHS in children. Adenotonsillectomy is the most common treatment for children with SAHS.RESUMEN:Los trastornos respiratorios del sueño en los niños, en particular el Síndrome de Apneas/Hipopneas durante el sueño (SAHS, es una patología frecuente, que afecta entre el 1 - 3% de la población infantil, siendo su causa más frecuente la hipertrofia adenoamigdalar. Es una enfermedad infradiagnosticada y que conlleva importantes complicaciones como son alteraciones del crecimiento, alteraciones cognitivas e incluso en casos severos Cor Pulmonale. La polisomnografía nocturna (PSG, es la técnica diagnóstica de elección para el diagnóstico del SAHS en los niños, pero en la población infantil es necesario tener en cuenta una serie de consideraciones, como son la edad de la población que se estudia, entorno adecuado y la necesidad de técnicos entrenados en el cuidado de los niños. Los criterios diagnósticos del SAHS para adultos no son útiles en los niños. El tratamiento de elección en los niños con SAHS es la adenoamigdalectomia.

  9. Nueve casos del sindrome HELLP (hemolisis, enzimas hepaticas Elevadas y plaquetopenia

    Directory of Open Access Journals (Sweden)

    M. F. Capellino

    2003-10-01

    Full Text Available El síndrome HELLP (hemólisis, enzimas hepáticas elevadas y plaquetopenia descripto por Weinstein en 1982, se asocia a alta morbi-mortalidad materna y perinatal. Se evaluaron retrospectivamente las pacientes que presentaron síndrome HELLP entre marzo 1998 y marzo 2001 en el Hospital Privado de Córdoba. Se identificaron nueve pacientes con Síndrome HELLP (incidencia 2.3‰. La edad media de las pacientes fue 24.5 años (15-36 con una edad gestacional media de 34.5 semanas (29-40. Cinco pacientes fueron nulíparas. El síntoma principal fue epigastralgia (77.7%. El parto fue por cesárea en siete pacientes y tres tuvieron síndrome HELLP post-parto. Tres pacientes presentaron hipertensión de difícil manejo, una eclampsia y otra coagulación intravascular diseminada, insuficiencia renal aguda y muerte. Tres requirieron transfusión de derivados sanguíneos y el promedio de internación fue 4.4 días. Seis (75% neonatos fueron pretérmino. El peso medio de nacimiento fue 2030 gramos (736-3200. Cuatro recién nacidos tuvieron un score de Apgar menor de 7 al minuto y todos mayor de 7 a los cinco minutos. Tres neonatos presentaron trastornos alimentarios, uno hipoglucemia y otro enfermedad de membrana hialina, ductus arterioso permeable, sepsis y plaquetopenia. Debido a la morbi-mortalidad materna y perinatal el síndrome HELLP requiere atención en un centro de alta complejidad mediante un equipo multidisciplinario.HELLP syndrome (Hemolysis, Elevated Liver Enzymes and Low Platelets was described by Weinstein in 1982. It has a high maternal and perinatal morbi-mortality rate. We undertook this study to evaluate perinatal outcome in patients with HELLP syndrome. Patients with HELLP syndrome were identified in a retrospective study between March 1998 and March 2001 at the Hospital Privado de Córdoba. Maternal and neonatal variables were analized. Nine patients with HELLP syndrome were identified (incidence 2.3‰. Mean maternal age was 24.5 (15-36 years. Five patients were nuliparous. The mean gestacional age was 34.5 weeks (29-40. The main symptom was epigastric pain (77.7%. In seven women delivery was made by cesarean section. Three patients had postpartum HELLP syndrome. Three patients had difficult control hypertension; one had eclampsia and another one had disseminated intravascular coagulopathy with acute renal failure and died. Three women needed blood products transfusions. The average admission time was 4.4 days. There were six preterm infants (75%. Mean birth weight was 2030 g (736-3200. Four neonates had Apgar score 7 at 5 minutes. Three neonates had alimentary disorders, one had hypoglucemia and another hyaline membrane disease, patent ductus arteriosus, sepsis and thrombocytopenia. The high maternal and perinatal morbi-mortality of HELLP syndrome requires management in a centre where intensive maternal and neonatal care are available.

  10. Giperkortitsizm i metabolicheskiy sindrom: slozhnosti differentsial'noy diagnostiki i lecheniya

    Directory of Open Access Journals (Sweden)

    2012-06-01

    Full Text Available Hypercortisolism is a severe endocrine disorder that leads to all types of metabolic disturbances. The most frequent symptom of hypercortisolism is a specific weight gain and body fat distribution - "cushingoid" obesity which clinically reflects the pathological changes in protein, carbohydrate and lipids metabolism. We provide a clinical case of a patient with Cushing's disease. This clinical case represents challenges in the differential diagnosis of this rare endocrine disorder and metabolic syndrome, and specific approach in further evaluation and treatment of Cushing's disease that requires all the latest technology in this field to be employed.

  11. Sindrome confusional agudo por abstinencia aguda de nicotina Delirium due to acute nicotine withdrawal

    Directory of Open Access Journals (Sweden)

    Manuel Klein

    2002-08-01

    Full Text Available El síndrome confusional agudo (SCA o delirium en pacientes hospitalizados es un problema frecuente y grave. Se caracteriza por síntomas de comienzo agudo y curso fluctuante con inatención, pensamiento desorganizado, y con distintos niveles de alteración de la conciencia.En la bibliografía consultada, el SCA como manifestación de un síndrome de abstinencia aguda nicotínica fue descripto en solo ocho casos. Presentamos el caso de un tabaquista grave que, internado por una reagudización de su enfermedad pulmonar obstructiva crónica (EPOC, presentó un cuadro de SCA al tercer día de abstinencia tabacal, cediendo los síntomas tras la administración de un parche de nicotina. Lo descripto sugiere que en pacientes internados que presentan SCA y agitación, con fuertes antecedentes de tabaquismo, un simple ensayo con un parche de nicotina puede ofrecer en pocas horas una notable respuesta terapéutica y a su vez un test confirmatorio. El reconocimiento del SCA como forma de presentación de la abstinencia nicotínica permitirá identificar casos habitualmente complejos en los que se podrá implementar una sencilla y eficaz alternativa terapéutica.Delirium or acute confusional state among hospitalized patients is a frequent and serious problem. It is characterized by acute onset symptoms, fluctuating course, impaired attention, unorganized thinking, and altered level of conciousness. Delirium, as a manifestation of acute nicotine withdrawal syndrome has been reported in the reviewed literature only in eight cases. We report the case of a heavy smoker admitted because of a reagudization of his chronic obstructive pulmonary disease. At the third day of nicotine abstinence, he developed delirium with a rapid improvement of his symptoms after treatment with a transdermal nicotine patch. This description suggests that in hospitalized heavy smokers who develop delirium with agitation, a simple trial with a nicotine patch can offer a dramatic therapeutic response in a few hours, constituing additionally a confirmatory test. The recognition of delirium as a manifestation of nicotine withdrawal could allow to determine the origin of symptoms and to apply the appropriate therapy, in certain complex cases that now remain undiagnosed.

  12. Asupan zink dan magnesium makanan dengan disfungsi ereksi pada penderita sindrom metabolik

    Directory of Open Access Journals (Sweden)

    Saraheni Saraheni

    2014-01-01

    Full Text Available Background: Metabolic syndrome (MetS is a disease of disorder of lipid and nonlipid metabolism. The West of Scotland Coronary Prevention Study found that men with MetS had probability 3.7 dysfunctions of erection (ED by using International Index of Erectile Function (IIEF. Patient with heart disease had the risk 2 times to get ED, hypertension was 1.5-2 times, DM was 3-4 times, depression was 2-3.5 times, testosterone deficiency syndrome (TDS was 1.5-2 times, and high cholesterol was 4 times. The nutrient deficiency of zinc (Zn and magnesium (Mg was suspected being the main component which had a role in resisting a sexuality growth and maturation process. Objective: Knowing the correlation of Zn and Mg feeding with erection dysfunction in MetS person. Method: This study was observational analytic study, with case-control design in the patient aged 30-60 years old. The respondent in this study was people with MetS according to WHO criterion. There was 82 patient divided into two groups, consist of 41 cases of MetS and ED, 41 cases with the normal patient. The data collected by interview, laboratory assessment and anthropometric measurement. The data analysis using univariate, bivariate and multivariate analysis using multiple logistic regression. Results: There was significant correlation between Zn feeding and ED (OR=7.15; 95% Cl=1.47-34.71; p=0.007 and there was significant correlation between Mg feeding with ED (OR=3.34; 95% Cl=1.07-10.4; p=0.033. The end result of the multivariate analysis showed the risk variable to the ED event, that was Zn feeding with OR=15.41. If the intake of Zn accompanied with risk factors associated as a cause of ED, multivariate analysis showed HbA1c’s degree with OR=12.57; triglyceride (OR=10.47; blood pressure (OR=5.82; and abdominal obesity (OR=6.94. The result shows that these risk factors can aggravate or anticipate the onset of dysfunction erection beside low Zn intake. Conclusion: There was statistically significant correlation between Zn and Mg feeding with erection dysfunction in MetS patient.

  13. SINDROME PARANEOPLASICO EN CANCER DE CABEZA Y CUELLO: REPORTE DE UN CASO

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    Danilo Terán Muñoz

    2018-05-01

    Full Text Available Introducción y objetivo:Presentamos el caso de una paciente que presentó un síndrome paraneoplásico como primera manifestación de un carcinoma epidermoide Materiales y Métodos:Varón de 57 años de edad, que  es ingresado en el servicio de neumología por presentar disnea de larga evolución junto a derrame pleural bilateral y artritis en rodillas, carpos y metacarpos de reciente aparición.  Durante su hospitalización presenta eritema y descamación en manos, pabellones auriculares, rodillas y muslos; se objetivó también un mínimo derrame pericárdico.  La analítica de autoinmunidad revelo anticuerpos antinucleares positivos y  Anti Ro positivo, siendo el resto de pruebas normales.  Las lesiones cutáneas son diagnosticadas como queratosis paraneoplásica de Basex.  La exploración física del paciente reveló la presencia de una masa cervical derecha dura y adherida, no objetivándose lesiones faringolaríngeas ni en otras localizaciones.  Se realiza una punción con aguja gruesa de la masa cervical, siendo el resultado del análisis anatomopatológico carcinoma epidermoide.  La lesión es catalogada como metástasis cervical de orígen desconocido. Discusión:Las manifestaciones clínicas sistémicas por los metabolitos de los tumores son denominadas síndromes paraneoplásicos.  Las diferentes metabolitos producidos pueden provocar un amplio abanico de síntomas, generalmente mediados por la acción toxica de las sustancias liberadas por el tumor.  Suelen afectar varios órganos y sistemas: endocrinos, dermatológicos, oculares y osteoarticulares.  Los síndromes paraneoplásicos ocurren en el 1 a 7,4% de todos los pacientes con cáncer, siendo la presentación en las neoplasias de cabeza y cuello infrecuente.  El carcinoma epidermoide es la variante asociada con más frecuencia a este tipo de síndromes, también presentándose con frecuencia en tumores neuroendocrinos,  siendo menor la incidencia en otro tipo de tumores como el adenocarcinoma, carcinoma adenoide quístico, linfomas y sarcomas.  La acroqueratosis paraneoplásica de Basex, fue descrita por primera vez en 1965, siendo asociada a carcinoma del seno piriforme.  Clínicamente se caracteriza por placas cutáneas descamativas eritematosas con predilección en extremidades y es el síndrome paraneoplásico que se presenta más frecuentemente en los tumores de laringe e hipofaringe. Conclusión:Los facultativos que tratan pacientes oncológicos deben ser capaces de diferenciar los síndromes paraneoplásicos de otros desórdenes benignos; estos síndromes pueden dominar el cuadro clínico del paciente llevando a una demora diagnóstica puesto que esta sintomatología eclipsa la patología oncológica de base.  El conocimiento de los síndromes paraneoplásicos es importante porque permite orientar el caso correctamente, para de esta manera realizar un diagnóstico precoz y un tratamiento orientado a la patología  del paciente.

  14. VALIDASI PEMERIKSAAN INFEKSI MENULAR SEKSUAL SECARA PENDEKATAN SINDROM PADA KELOMPOK WANITA BERPERILAKU RISIKO TINGGI

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    Endang R. Sedyaningsih Mamahit

    2012-09-01

    Full Text Available Accurate and adequate treatment of STIs is a critical component of STI-control activities to reduce transmission and sequelaes. On the other hand, chronic shortage in skilled staff and laboratory equipment in many countries necessitate the use of clinical skills more in order to diagnose and differentiate STIs. For these places, the WHO has recommended and produced a protocol of it syndromic approach management of STIs in place of treatment by -etiology. Since 1997 the Indonesia Ministry of Health has been conducting national training on this method. However, the syndromic approach for vaginal discharge is known to be problematic since differentiation among cervicitis, vaginitis, and even normal condition is difficult. The main objective of this study is to determine the sensitivity, specificity and positive predictive value of the syndromic approach management of women with signs and/or symptoms of abnormal vaginal discharge. The sample population were women with high risk sexual behaviors in East Java and North Sulawesi provinces. The laboratory tests using DNA hybridization probe technique (the PACE 2 test, Gen-Probe, San Diego, Calif. for Neisseria gonorrhoeae and Chlamydia trachomatis were used as gold standard. In addition, we also compared the clinical approach widely used by clinicians (mainly at hospitals with laboratory results. A total of 439 participants was recruited purposively (230 from E. Java and 209 from N.Sulawesi. In E.Java, the sensitivity, specificity, and predictive value of the syndromic management for vaginal discharge are 31%, 83%, and 59%, respectively, and in N.Sulawesi 49%, 56%, and 40%,respectively. The clinical approach did not show better results. In E.Java the sensitivity, specificity, and positive predictive value are 13%, 89%, and 50%, res­pectively, while in N.Sulawesi they are 42%, 61%, and 39%, respectively. As a conclusion, the current form of syndromic management has little use for STI screening among high risk women. Further studies by adding more criteria to the syndromes are needed to improve this method.

  15. Radiological pulmonary manifestations of acquired immunodeficiency syndrome; Manifestacoes radiologicas pulmonares da sindrome da imunodeficiencia adquirida

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    Marchiori, Edson; Melo, Alessandro Severo Alves de; Ossa, Alfonso Jaramillo [Universidade Federal Fluminense, Niteroi, RJ (Brazil). Dept. de Radiologia

    1999-06-01

    In this article are reviewed the principal radiologic manifestations of inflammatory and tumoral diseases the compromise the lungs of patients with acquired immunodeficiency syndrome. In the group of inflammatory diseases the radiologic aspects of pneumocystosis, cytomegalovirus disease, cryptococcosis, tuberculosis and bacterial pneumonias are emphasized. In the neoplasic diseases' group the aspects of lymphoma and Kaposi's sarcoma are specially presented. (author)

  16. CHILD ABUSE IN A MEDICAL SETTING: CASE ILLUSTRATIONS OF TWO VARIANTS OF MUNCHAUSEN SINDROME BY PROXY.

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    Antonietta Lanzarone

    2017-04-01

    Full Text Available Munchausen syndrome is a complex type of abuse, which is often underdiagnosed or misdiagnosed in clinical practice, and has harmful consequences for children. Its relationship with child abuse, of which it is a variety, must be recognized in clinical and forensic practice. The authors report herein two observed cases of different types of Münchausen syndrome by proxy (MSbP. The first, is the most severe form of MSbP, with induced, true illness and related pathological symptoms into victim. The second case is a moderate form, much more complex to detect, in which a perpetrator parent simulates and aggravates the child‘s illness. Adequate training of health professionals and investigators is essential in revealing cases of MSbP. Diagnosis must be based on the study of the different forms of "abuse" and the knowledge of clinical protocols used to validate any suspected behaviour which could be potentially harmful to the child. Moreover, a lack of training may lead to misleading interpretations of medical history interpretation and fallacious conclusions. Our study aims to review the features that are to be considered in a suspected case of MSbP, in accordance with a recently updated consensus statement by the Committee on Child Abuse and Neglect from the American Academy of Pediatrics.

  17. Penatalaksanaan Oligodontia pada Anak 14 Tahun dengan Sindrom Ectodermal Dysplasia: Laporan Kasus

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    Anie Apriani

    2015-12-01

    Full Text Available Ectodermal dysplasia is a hereditary disorder that is rarely seen with approximately 7000 cases in the world. In this disorder, Ectodermal dysplasia occurs as a developmental disorder of organ structures derived from the ectodermal layer such as hair, teeth, nails, and sweat glands. This is a case report of ectodermal dysplasia in a 14-year-old girl with clinical manifestations of oligodontia (tooth loss, more than 6 teeth on the upper and lower jaw, thin and curly hair, abnormal toenail shape, and impaired excretion of sweat. The purpose of the treatment was to make the patient regains her esthetic and masticatory functions, which were disrupted by the absence of permanent tooth buds, as well as to maintain the normal growth of the developing jaws. Treatment for the patient’s with oligodontia included the use of removable denture in lower jaw and application of acrylic crowns on all upper and lower anterior teeth resulting in improved esthetics and masticatory function. It is concluded that the treatment has been able to improve the esthetics and to return the masticatory function of the patient while maintaining the normal growth of the jaws.

  18. Sindrome de Landau Kleffner aspectos clinicos, eletrencefalograficos e psicossociais : estudo de seguimento a longo prazo

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    Marcos Henrique Coelho Duran

    2008-01-01

    Resumo: Objetivos: A Síndrome de Landau-Kleffner (SLK) é uma entidade rara, caracterizada por epilepsia e afasia. Ocorre em crianças com aquisição normal da linguagem, geralmente, entre 3 e 7 anos de idade. A evolução a longo prazo é controversa e pouco estudada. O presente estudo tem como objetivo verificar a evolução em uma série de sujeitos com diagnóstico de SLK, enfocando os aspectos clínicos, eletrencefalográficos, psicossociais e da qualidade de vida. Métodos: Trata-se de um estudo tra...

  19. HUBUNGAN MASA KERJA DAN SIKAP KERJA DENGAN KEJADIAN SINDROM KARPAL PADA PEMBATIK CV. PUSAKA BERUANG LASEM

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    Cris Purwandari Mulyawati Agustin

    2014-10-01

    Full Text Available Pembatik merupakan pekerja sektor informal, dimana pada saat membatik melakukan gerakan berulang, gerakan tangan dengan kekuatan, posisi fleksi dan ekstensi, sehingga menyebabkan stress pada jaringan disekitar terowongan karpal. Tujuan penelitian ini untuk mengetahui hubungan masa kerja dan sikap kerja dengan kejadian STK pada pembatik CV. Pusaka Beruang.Penelitian ini menggunakan pendekatan cross sectional. Populasi dalam penelitian berjumlah 68 orang. Sampel penelitian berjumlah 22 responden. Instrument penelitian berupa kuesioner dan pengukuran tes phalen. Data dianalisis dengan uji Chi-square.Hasil penelitian menunjukkan bahwa ada hubungan masa kerja p=0,029 dan sikap kerja p=0,031 dengan kejadian STK. Masa kerja > 4 tahun dan level sikap kerja yang tinggi mempunyai risiko STK karena terjadi stress disekitar jaringan terowongan karpal.Simpulan pada penelitian ini ada hubungan antara masa kerja dan sikap kerja dengan kejadian STK. Saran untuk pekerja diharapkan dapat melakukan istirahat secara teratur setiap 15-20 menit untuk mengurangi risiko STK. Batik is an informal sector workers describe or designed batik with the traditional way of working. Which time both do repetitive motion, hand movements with strength, position, position the extension and flexion, hand static, thus causing stress on the network around the carpal tunnel. The purpose of this research is to know the relation tenure and working attitude with STK batik meker in CV. Pusaka Beruang. This research uses the approach of cross sectional. The population in this research is totalling 68 peoples. Sample research amounted to 22 respondents. Research Instrument in the form of questionnaires and measurement test phalen. Data were analyzed by Chi square test. The results showed that there was a relationship tenure p = 0.029 and working attitude p = 0.031 with STK events. Tenure > 4 years and a high level of work attitudes have STK risk due to stress around the carpal tunnel syndrome network.The conclusions in this study no relationship tenure and work attitude with STK. Advice for workers expected to perform regular breaks every 15-20 minutes to reduce the risk of STK.

  20. Upaya Peningkatan Tingkat Pengetahuan Siswi MAN 2 Palembang Mengenai Sindrom Pra Menstruasi

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    Muhammad Aditya Alfarizki

    2017-03-01

    Full Text Available Premenstrual syndrome characterized by affective, physical, and behavior symptoms with moderate to severe grade, that usually recurrent every luteal phase of menstrual cycle and disappear within menstruation. The frequency of premenstrual syndrome is still high, in Indonesia and all over the world. To overcome this situation, there should be a health promotion. The aim of this community service was to increase the girl’s knowledge of premenstrual syndrome. This community service was held in one day on November 2016 in public islamic high school MAN 2 Palembang. The schedule was start with pre test consist of 15 questions, counseling sesssion using power point media, discussion session, and post test consist of the same questions to measure the knowledge after counseling. Pre test score showed that 13.9% students had good knowledge and post test score showed an increase of good knowledge (66.7%. Conclusion, heatlh education through counseling method bring a change of knowledge.