Sample records for 修复途径 (repair pathways)

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Assessment of the significance of mitochondrial DNA damage by chemotherapeutic agents

Lo, S; Tolner, B; Taanman, JW; Cooper, JM; Gu, M; Hartley, JA; Schapira, AHV; Hochhauser, D

The pathways which are activated following damage to nuclear DNA in cancer cells are well understood. There is evidence that treatment with several chemotherapeutic agents may result in damage to mitochondrial DNA. This study investigated the contribution of mitochondrial DNA to cytotoxicity of DNA-...

DRIVER (Chinese)