Sample records for 嘧啶二聚物 (pyrimidine dimers)
from WorldWideScience.org

Sample records 1 - 11 shown.



5

UVA-induced cyclobutane pyrimidine dimers form predominantly at thymine–thymine dipyrimidines and correlate with the mutation spectrum in rodent cells

Perdiz, Daniel; Rochette, Patrick J.; Drouin, Régen; Therrien, Jean-Philippe; Bastien, Nathalie; Drobetsky, Elliot A.

Ligation-mediated PCR was employed to quantify cyclobutane pyrimidine dimer (CPD) formation at nucleotide resolution along exon 2 of the adenine phosphoribosyltransferase (aprt) locus in Chinese hamster ovary (CHO) cells following irradiation with either UVA (340–400 nm), UVB (295–320 nm), UVC (254 ...

DRIVER (Chinese)

9

Human repair gene restores normal pattern of preferential DNA repair in repair defective CHO cells.

Hanawalt, P C; Bohr, V A; van Duin, M; Chu, E H; Okumoto, D S

The pattern of preferential DNA repair of UV-induced pyrimidine dimers was studied in repair-deficient Chinese hamster ovary (CHO) cells transfected with the human excision repair gene, ERCC-1. Repair efficiency was measured in the active dihydrofolate reductase (DHFR) gene and in its flanking, non-...

DRIVER (Chinese)

11

Demethylation enhances removal of pyrimidine dimers from the overall genome and from specific DNA sequences in Chinese hamster ovary cells.

Ho, L; Hanawalt, P C; Bohr, V A

We have examined the effects of changes in cytosine methylation on DNA repair in UV-irradiated Chinese hamster ovary (CHO) cells. A hypomethylated derivative of the CHO K1B11 line, B11aza, was established by passaging B11 cells over several months in increasing concentrations of 5-azacytidine; great...

DRIVER (Chinese)