Sample records for 微粒体 (microsomes)

Sample records 1 - 11 shown.


Stereoselective glucuronidation of carvedilol by Chinese liver microsomes*

Chen, Shu-qing; You, Lin-ya; Xie, Sheng-gu; Yu, Chun-na; Zeng, Su

Objective: To study the stereoselective glucuronidation of carvedilol (CARV) by three Chinese liver microsomes. Methods: The metabolites of CARV were identified by a hydrolysis reaction with β-glucuronidase and HPLC-MS/MS. The enzyme kinetics for CARV enantiomers glucuronidation was determined by a ...

DRIVER (Chinese)