Sample records for 小鼠 (mice)
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34

Transgenic mice with overexpression of human scavenger receptor A on endothelial cells

Wan, L; Chung, SK; Yang, JY; Chung, SSM; Cao, D; Ma, MKL; Wu, M; Chen, X

DRIVER (Chinese)

37

Therapeutic impact of the ethyl acetate extract of Tripterygium wilfordii Hook F on nephritis in NZB/W F1 mice

Longo, Nancy S; Tao, Xuelian; Hoffmann, Victoria; Fan, Fred; Lipsky, Peter E

This study was designed to examine the potential use of the ethyl acetate (EA) extract of Tripterygium wilfordii Hook F (TwHF), a Chinese herbal medicine, in the treatment of systemic lupus erythematosus. A total of 48 28-week-old female NZB/W F1 mice were randomly divided into three groups and oral...

DRIVER (Chinese)

40

The natural killer gene complex genetic locus Chok encodes Ly-49D, a target recognition receptor that activates natural killing

Ortaldo, John R.; Idris, Azza H.; Mason, Llewellyn H.; Smith, Hamish R. C.; Scalzo, Anthony A.; Yokoyama, Wayne M.

Previously, we established that natural killer (NK) cells from C57BL/6 (B6), but not BALB/c, mice lysed Chinese hamster ovary (CHO) cells, and we mapped the locus that determines this differential CHO-killing capacity to the NK gene complex on chromosome 6. The localization of Chok in the NK gene co...

DRIVER (Chinese)

41

The antidiabetic effects of a dry powder of dietary vegetable and fruit mixtures in diabetic db/db mice

Yeung, CM; Tan, Y; Tam, S; Lu, L; Ko, KH; Yang, PH; Kung, HF; Lin, MC

We evaluated the antidiabetic effects of a mixed vegetable powder-formula I (MVP-FI), which is a dry powder mixture of over 65 kinds of vegetables and fruits, using the db/db type 2 diabetes mouse model. The db/db mice at 8–10 weeks of age were randomly divided into three groups: vehicle treatment, ...

DRIVER (Chinese)

42

TNFalpha-Polymorphismus bei Patienten mit Sepsis und Schilddrüsenkarzinomen

Rossbach, Christiane

Das Zytokin Tumornekrosefaktor a (TNFa) hat einen entscheidenden Anteil an der Entwicklung schwerer Komplikationen, wie septischer Schock und Multiorganversagen nach Entwicklung einer Sepsis. Eine Assoziation des TNF2-Allels mit einem erhöhten TNF a Spiegel und einer höheren Mortalitätsrate wurde i...

DRIVER (Chinese)

44

Study of Gene-Targeted Mouse Models of Splicing Factor Gene Prpf31 Implicated in Human Autosomal Dominant Retinitis Pigmentosa (RP)

Bujakowska, K; Maubaret, C; Chakarova, CF; Tanimoto, N; Beck, SC; Fahl, E; Humphries, MM; Kenna, PF; Makarov, E; Makarova, O

PURPOSE. Pre-mRNA processing factor 31 (PRPF31) is a ubiquitous protein needed for the assembly of the pre-mRNA splicing machinery. It has been shown that mutations in this gene cause autosomal dominant retinitis pigmentosa 11 (RP11), which is characterized by rod-cell degeneration. Interestingly, m...

DRIVER (Chinese)

45

Psychological Stress-Induced Oxidative Stress as a Model of Sub-Healthy Condition and the Effect of TCM

Shirakawa, Chieko; Wang, Lei; Nishida, Hiroshi; Muxin, Gong; Sato, Shinji; Konishi, Tetsuya

Distress-mediated tissue oxidative stress was examined as a model of sub-healthy condition defined in traditional Chinese medicine theory. Mice were subjected to psychologically stressful conditions by whiskers removal. Under this condition, spontaneous locomotive activity was significantly enhanced...

DRIVER (Chinese)

46

Presence and transcription of intracisternal A-particle-related sequences in CHO cells.

Williams, S R; Anderson, K P; Low, M A; Lie, Y S; Fennie, E H; Nguyen, T P; Wurm, F M

We have characterized sequences expressed in Chinese hamster ovary (CHO) cells which are related to the intracisternal A-particle (IAP) genes of mice and Syrian hamsters. Several cDNA clones homologous to Syrian hamster IAP probes have been isolated and used to evaluate the abundance and expression ...

DRIVER (Chinese)

47

Presence and transcription of intracisternal A-particle-related sequences in CHO cells

Anderson, K. P.; Lie, Y. S.; Low, M. A.; Williams, S. R.; Fennie, E. H.; Nguyen, T. P.; Wurm, F. M.

We have characterized sequences expressed in Chinese hamster ovary (CHO) cells which are related to the intracisternal A-particle (IAP) genes of mice and Syrian hamsters. Several cDNA clones homologous to Syrian hamster IAP probes have been isolated and used to evaluate the abundance and expression ...

DRIVER (Chinese)

48

Posttranslational processing of recombinant human interferon-gamma in animal expression systems.

Jenkins, N.; James, D. C.; Hoare, M.; Goldman, M. H.; Oliver, R. W.; Green, B. N.; Freedman, R. B.

We have characterized the heterogeneity of recombinant human interferon-gamma (IFN-gamma) produced by three expression systems: Chinese hamster ovary cells, the mammary gland of transgenic mice, and baculovirus-infected Spodopera frugiperda (Sf9) insect cells. Analyses of whole IFN-gamma proteins by...

DRIVER (Chinese)

49

Posttranslational processing of recombinant human interferon-gamma in animal expression systems

James, DC; Goldman, MH; Hoare, M; Jenkins, N; Oliver, RWA; Green, BN; Freedman, RB

We have characterized the heterogeneity of recombinant human interferon-gamma (IFN-gamma) produced by three expression systems: Chinese hamster ovary cells, the mammary gland of transgenic mice, and baculovirus-infected Spodoptera frugiperda (Sf9) insect cells. Analyses of whole IFN-gamma proteins b...

DRIVER (Chinese)

51

On Microvascular Inflammation and Intestinal Leakage in Radiation Enteropathy

Röme, Andrada

Gastrointestinal tract damage is an insidious feature in patients undergoing radiotherapy. Microvascular inflammation, including leukocyte and platelet recruitment as well as epithelial barrier dysfunction, are considered to constitute key components in the pathophysiology of radiation-induced enter...

DRIVER (Chinese)

53

N-GLYCOSYLATION OF RECOMBINANT HUMAN INTERFERON-GAMMA PRODUCED IN DIFFERENT ANIMAL EXPRESSION SYSTEMS

JAMES, DC; FREEDMAN, RB; HOARE, M; OGONAH, OW; ROONEY, BC; LARIONOV, OA; DOBROVOLSKY, VN; LAGUTIN, OV; JENKINS, N

Recombinant human interferon-gamma (IFN-gamma) was expressed in Chinese hamster ovary cells, baculovirus-infected Sf9 insect cells and the mammary gland of transgenic mice, The N-linked carbohydrate populations associated with both Asn(25), and Asn(97) glycosylation sites were characterized by matri...

DRIVER (Chinese)

55

Licochalcone A, a new antimalarial agent, inhibits in vitro growth of the human malaria parasite Plasmodium falciparum and protects mice from P. yoelii infection.

Hviid, L; Chen, M; Christensen, S B; Theander, T G; Zhai, L; Kharazmi, A

Licochalcone A, isolated from Chinese licorice roots, inhibited the in vitro growth of both chloroquine-susceptible (3D7) and chloroquine-resistant (Dd2) Plasmodium falciparum strains in a [3H]hypoxanthine uptake assay. The growth inhibition of the chloroquine-resistant strain by licochalcone A was ...

DRIVER (Chinese)

56

Inhibin interferes with activin signaling at the level of the activin receptor complex in Chinese hamster ovary cells

Martens, J.W.M.; Winter, J.P. de; Timmerman, M.A.; McLuskey, A.; Schaik, R.H.N. van; Themmen, A.P.N.; Jong, F.H. de

DRIVER (Chinese)

58

Genome-wide haplotype association mapping in mice identifies a genetic variant in CER1 associated with bone mineral density and fracture in southern Chinese women.

Tang, PLF; Cheung, CL; Sham, PC; McClurg, P; Lee, BBC; Chan, SY; Smith, DK; Tanner, JA; Su, AI; Cheah, KSE; Kung, AWC; Song, Y

DRIVER (Chinese)

63

Evaluation of pseudorabies virus glycoprotein gp50 as a vaccine for Aujeszky's disease in mice and swine: expression by vaccinia virus and Chinese hamster ovary cells.

Timmins, J G; Marchioli, C C; Petrovskis, E A; Yancey, R J; Post, L E

Pseudorabies virus (PRV) is an alphaherpesvirus which causes an economically important disease of swine. One of the PRV glycoproteins, gp50, was previously identified as the sequence homolog of herpes simplex virus glycoprotein gD (E.A. Petrovskis, J.G. Timmins, M.A. Armentrout, C.C. Marchioli, R.J....

DRIVER (Chinese)

64

Effects of the Chinese Traditional Medicine Mao-Bushi-Saishin-To on Therapeutic Efficacy of a New Benzoxazinorifamycin, KRM-1648, against Mycobacterium avium Infection in Mice

Shibata, Hiroki; Yamada, Yoshitaka; Sano, Chiaki; Shimizu, Toshiaki; Higashi, Natsumi; Sato, Katsumasa; Tomioka, Haruaki

The Chinese traditional medicine mao-bushi-saishin-to (MBST), which has anti-inflammatory effects and has been used to treat the common cold and nasal allergy in Japan, was examined for its effects on the therapeutic activity of a new benzoxazinorifamycin, KRM-1648 (KRM), against Mycobacterium avium...

DRIVER (Chinese)

70

Distribution of endogenous murine leukemia virus DNA sequences among mouse chromosomes.

Ruddle, F; Jolicoeur, P; Kozak, C; Rassart, E; Baltimore, D

We used mouse-Chinese hamster somatic cell hybrids which lose mouse chromosomes to examine the distribution of murine leukemia virus DNA sequences in the genome of A/HeJ mice. We analyzed total cellular DNA from various hybrid clones for the presence of viral sequences by molecular hybridization and...

DRIVER (Chinese)

72

Deregulation of hamster fibroblast proliferation by mutated ras oncogenes is not mediated by constitutive activation of phosphoinositide-specific phospholipase C.

Seuwen, K; Pouysségur, J; Lagarde, A

Stable expression of high levels of activated forms of Haras (T24) or v-Ki-ras by transfection of Chinese hamster lung fibroblasts (CCL39) yielded cells highly tumorigenic in nude mice. Two classes of transformed cells were distinguished, one with moderate p21 expression (10-fold increased) had reta...

DRIVER (Chinese)

77

Cholera toxin treatment stimulates tumorigenicity of Rous sarcoma virus-transformed cells.

Pastan, I; Gottesman, M M; Vlahakis, G; Roth, C

Chinese hamster ovary cells transformed by Rous sarcoma virus form tumors poorly in nude mice. Tumorigenicity was markedly stimulated by pretreatment of the cells with cholera toxin, which raises cyclic AMP levels and activates cyclic AMP-dependent protein kinase. Increased tumorigenicity was manife...

DRIVER (Chinese)

79

An atypical kindred with X-linked adrenal hypoplasia congenita, normal puberty, and normal Dax-1 promoter and coding sequence

Loke, KY; Poh, KSL; Walker, AP; Tan, JAMA; Tay, AHN

We report a Chinese kindred with an atypical sex-linked form of isolated adrenal hypoplasia without hypogonadotropic hypogonadism, Evidence of sex linkage was supported by DNA analysis using three polymorphic markers from the X-chromosome: a restriction fragment length polymorphism 200 kb centromeri...

DRIVER (Chinese)

80

An RNA polymerase I promoter located in the CHO and mouse ribosomal DNA spacers: functional analysis and factor and sequence requirements.

Wejksnora, P J; Tower, J; Dougherty, K M; Henderson, S L; Sollner-Webb, B

We report results of experiments in which we demonstrated the existence of a polymerase I promoter within the ribosomal DNA spacer upstream from the rRNA initiation site in Chinese hamsters and mice. Transcription of the CHO spacer promoter was achieved by the same protein factors, C and D, that cat...

DRIVER (Chinese)

81

Acquisition of two endogenous ecotropic murine leukemia viruses in distinct Asian wild mouse populations.

Huai, W C; Inaguma, Y; Moriwaki, K; Miyashita, N; Jin, M L; He, X Q; Ikeda, H

Wild mouse DNAs were analyzed for two types of endogenous ecotropic murine leukemia viruses (MuLVs), Akv and Fv-4r-associated MuLV. Endogenous Akv viruses were found only in northern Chinese mice, Korean mice, and Japanese (Mus musculus molossinus) mice. The Fv-4r gene, which is a truncated endogeno...

DRIVER (Chinese)

82

Sinn, Wai-hang; 冼惠恆

DRIVER (Chinese)

83

Sinn, Wai-hang; 冼惠恆

DRIVER (Chinese)

84

Leung, Sze-wan; 梁詩韻

DRIVER (Chinese)

85

Leung, Sze-wan; 梁詩韻

DRIVER (Chinese)

86

Fu, Yu; 傅玉

DRIVER (Chinese)

87

Chu, Yuet-wah; 朱月華

DRIVER (Chinese)

88

Choy, Hau-tim; 蔡孝添

DRIVER (Chinese)