Sample records for 免疫疗法 (immunotherapy)

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TNFalpha-Polymorphismus bei Patienten mit Sepsis und Schilddrüsenkarzinomen

Rossbach, Christiane

Das Zytokin Tumornekrosefaktor a (TNFa) hat einen entscheidenden Anteil an der Entwicklung schwerer Komplikationen, wie septischer Schock und Multiorganversagen nach Entwicklung einer Sepsis. Eine Assoziation des TNF2-Allels mit einem erhöhten TNF a Spiegel und einer höheren Mortalitätsrate wurde i...

DRIVER (Chinese)


Functional Inactivation of EBV-Specific T-Lymphocytes in Nasopharyngeal Carcinoma: Implications for Tumor Immunotherapy

Zeng, Mu-sheng; Wang, Xiao-ning; Huang, Wen-lin; Zeng, Yi-Xin; Gao, Yan-fang; Zhang, Xiao-shi; Rolén, Ulrika; Li, Jiang

Nasopharyngeal carcinoma (NPC) is an Epstein-Barr virus (EBV) associated malignancy with high prevalence in Southern Chinese. In order to assess whether defects of EBV-specific immunity may contribute to the tumor, the phenotype and function of circulating T-cells and tumor infiltrating lymphocytes ...

DRIVER (Chinese)


Enhancing immune responses for cancer therapy

Xue, SA; Stauss, HJ

Although the immune system possesses the means to respond to cancer, it often fails to control the spread of malignancy. Nonetheless, equipping endogenous immunity to release a strong antitumor response has significant advantages over conventional therapies. This review explores some of the options ...

DRIVER (Chinese)


Cancer immunotherapy targeting the telomerase reverse transcriptase

Huo, L; Tang, JW; Huang, JJ; Huang, PT; Huang, CF; Kung, HF; Lin, MC

DRIVER (Chinese)


CD4+ T-Cell Responses to Epstein-Barr Virus Nuclear Antigen EBNA1 in Chinese Populations Are Highly Focused on Novel C-Terminal Domain-Derived Epitopes

Rickinson, A. B.; Taylor, G. S.; Tsang, C. W.; Gudgeon, N. H.; Lin, X.; Jia, H.; Lin, C. K.; Hui, E. P.; Chan, A. T. C.

Epstein-Barr virus nuclear antigen EBNA1, the one viral protein uniformly expressed in nasopharyngeal carcinoma (NPC), represents a prime target for T-cell-based immunotherapy. However, little is known about the EBNA1 epitopes, particularly CD4 epitopes, presented by HLA alleles in Chinese people, t...

DRIVER (Chinese)