Sample records for 人X染色体 (human x chromosome)

Sample records 1 - 10 shown.


Thymidylate synthase-deficient Chinese hamster cells: a selection system for human chromosome 18 and experimental system for the study of thymidylate synthase regulation and fragile X expression.

Airhart, S D; Nussbaum, R L; Lesko, J G; Walmsley, R M; Ledbetter, D H

Chinese hamster lung (CHL) V79 cells already deficient in hypoxanthine phosphoribosyltransferase were exposed to uv light and selected for mutations causing deficiency of thymidylate synthase (TS) by their resistance to aminopterin in the presence of thymidine and limiting amounts of methyl tetrahyd...

DRIVER (Chinese)


Specific staining of human chromosomes in Chinese hamster x man hybrid cell lines demonstrates interphase chromosome territories

Schardin, Margit; Cremer, Thomas; Hager, H. D.; Lang, M.

In spite of Carl Rabl's (1885) and Theodor Boveri's (1909) early hypothesis that chromosomes occupy discrete territories or domains within the interphase nucleus, evidence in favor pf this hypothesis has been limited and indirect so far in higher plants and animals. The alternative possibility that ...

DRIVER (Chinese)


Regional localization of DNA sequences on chromosome 21 using somatic cell hybrids.

Jabs, E W; Van Keuren, M L; Drabkin, H A; Watkins, P C; Gusella, J F; Patterson, D

We have used a panel of Chinese hamster X human somatic cell hybrids, each containing various portions of chromosome 21 as the only detectable human chromosome component, for regional mapping of cloned, chromosome 21-derived DNA sequences. Thirty unique and very low-repeat sequences were mapped to t...

DRIVER (Chinese)


Isolation and mapping of 62 new RFLP markers on human chromosome 11.

Nakamura, Y; Tanigami, A; Tokino, T; Mori, M; Takahashi, E; Glaser, T; Hori, T; Park, J W; Jones, C

To obtain new RFLP markers on human chromosome 11 for a high-resolution map, we constructed a cosmid library from a Chinese hamster x human somatic hybrid cell line that retains only human chromosome 11 in a Chinese hamster genomic background. A total of 3,500 cosmids were isolated by colony hybridi...

DRIVER (Chinese)


Fine-scale map of encyclopedia of DNA elements regions in the Korean population.

Yoo, YK; Ke, X; Hong, S; Jang, HY; Park, K; Kim, S; Ahn, T; Lee, YD; Song, O; Rho, NY; Lee, MS; Lee, YS; Kim, J; Kim, YJ; Yang, JM

The International HapMap Project aims to generate detailed human genome variation maps by densely genotyping single-nucleotide polymorphisms (SNPs) in CEPH, Chinese, Japanese, and Yoruba samples. This will undoubtedly become an important facility for genetic studies of diseases and complex traits in...

DRIVER (Chinese)


Assignment of genes to the human X chromosome by the two-dimensional electrophoretic analysis of total cell proteins from rodent-human somatic cell hybrids.

Cox, D R; Epstein, C J; Francke, U

The technique of two-dimensional (2-D) gel electrophoresis was sued to identify five human X-linked gene products in crude cell extracts of mouse-human and Chinese hamster-human somatic cell hybrids. The human origin of these five polypeptides was demonstrated by their comigration with human fibrobl...

DRIVER (Chinese)


Aberrante Methylierung des p16INK4a-Promotors als Tumormarker für die molekularzytologische Diagnostik des Lungenkarzinoms an Bronchialaspiraten

Krücken, Anne

In der vorliegenden Arbeit wurde der Methylierungsstatus des p16INK4a-Promotors an Material der pulmonalen Exfoliativzytologie untersucht und seine Eignung als Tumormarker für die molekularzytologische Diagnostik des Lungenkarzinoms überprüft. Der Nachweis der p16INK4a-Promotor-Methylierung erfolgte...

DRIVER (Chinese)