Sample records for 人染色体 (human chromosomes)
from WorldWideScience.org

Sample records 1 - 20 shown. Select sample records:



6

The human gene for beta glucuronidase is on chromosome 7.

Francke, U

Inconsistent assignments of the human gene for beta glucuronidase (GUS) to chromosomes 7 and 9 have previously been reported. In this study, we have correlated the expression of human GUS in 22 primary Chinese hamster/human hybrid lines with quantitative cytogenetic analysis. Eight hybrids were posi...

DRIVER (Chinese)

7

Stable association of the human transgenome and host murine chromosomes demonstrated with trispecific microcell hybrids.

Fournier, R E; Ruddle, F H

Trispecific microcell hybrids were prepared by transferring limited numbers of chromosomes from a human/mouse gene-transfer cell line to a Chinese hamster recipient line. The donor cells employed were murine L-cells that stably expressed the human form of the enzyme hypoxanthine phosphoribosyltransf...

DRIVER (Chinese)

8

Specific staining of human chromosomes in Chinese hamster x man hybrid cell lines demonstrates interphase chromosome territories

Schardin, Margit; Cremer, Thomas; Hager, H. D.; Lang, M.

In spite of Carl Rabl's (1885) and Theodor Boveri's (1909) early hypothesis that chromosomes occupy discrete territories or domains within the interphase nucleus, evidence in favor pf this hypothesis has been limited and indirect so far in higher plants and animals. The alternative possibility that ...

DRIVER (Chinese)

9

Primitive small round cell tumour of the adrenal gland presenting with fever of unknown origin and t(12;22)(q13;q12) cytogenetic finding

Lam, KY; Lo, CY; Shek, TWH; Ma, ESK; Au, WY; Chan, GCF

This report describes a left adrenal tumour in a 16 year old Chinese girl who presented with fever of unknown origin. The histological and ultrastructural features of the adrenal tumour were those of a primitive small round cell tumour with neuroendocrine differentiation. Cytogenetic analysis of cul...

DRIVER (Chinese)

10

Microcell-mediated transfer of murine chromosomes into mouse, Chinese hamster, and human somatic cells.

Fournier, R E; Ruddle, F H

In this report, we describe the production and characterization of proliferating hybrid cell populations generated by fusion of murine microcells with intact mouse, Chinese hamster, and human recipient cells. The microcell hybrids so produced contained one to five intact murine chromosomes derived f...

DRIVER (Chinese)

12

Localization of the xeroderma pigmentosum group B-correcting gene ERCC-3 to human chromosome 2q21.

Weeda, G.; Wiegant, J.; Ploeg, M. van der; Geurts van Kessel, A.H.M.; Eb, A.J. van der; Hoeijmakers, J.H.J.

The human excision-repair gene ERCC3 was cloned after DNA-mediated gene transfer to the uv-sensitive Chinese hamster ovary mutant cell line 27-1, a member of complementation group 3 of the excision-defective rodent cell lines. The ERCC3 gene specifically corrects the DNA repair defect of xeroderma p...

DRIVER (Chinese)

13

Localization of the nucleotide excision repair gene ERCC-6 to human chromosome 10q11-q21.

Troelstra, C.; Landsvater, R.M.; Wiegant, J.; Ploeg, M. van der; Viel, G.; Buys, C.H.C.M.; Hoeijmakers, J.H.J.

We have cloned the human DNA excision repair gene ERCC6 by virtue of its ability to correct the uv sensitivity of Chinese hamster overy cell mutant UV61. This mutant is a member of complementation group 6 of the nucleotide excision repair-deficient rodent mutants. By means of in situ hybridization a...

DRIVER (Chinese)

15

Laser-UV-microirradiation of interphase nuclei and posttreatment with caffeine: a new approach to establish the arrangement of interphase chromosomes

Zorn, Christian; Cremer, Thomas; Cremer, Christoph; Zimmer, J.

Laser UV microirradiation of Chinese hamster interphase cells combined with caffeine post-treatment produced different patterns of chromosome damage in mitosis following irradiation of a small area of the nucleus that may be classified in three categories: I) intact metaphase figures, II) chromosome...

DRIVER (Chinese)

17

Genetics of somatic mammalian cells: genetic, immunologic, and biochemical analysis with Chinese hamster cell hybrids containing selected human chromosomes.

Kao, F T; Puck, T T; Jones, C

Through hybridization of specific Chinese hamster cell auxotrophs with human cells and selection in media lacking the nutritional supplements required by the former cells, a series of stable hybrid clones can be prepared. These hybrids have genomes consisting of a common part--the complete or almost...

DRIVER (Chinese)

24

Assignment of the AK1:Np:ABO linkage group to human chromosome 9.

van Someren, H; Westerveld, A; Meera Khan, P; Jongsma, A P; Bootsma, D

In man-Chinese hamster somatic cell hybrids the segregation patterns of the loci for 25 human enzyme markers and human chromosomes were studied. The results provide evidence for the localization of the gene for adenylate kinase-1 (AK1) on chromosome 9. Since the loci for the ABO blood group (ABO), n...

DRIVER (Chinese)

25

A study on the association of the chromosome 12p13 locus with sporadic late-onset Alzheimer's disease in Chinese

Li, Y; Chu, LW; Li, Z; Yik, PY; Song, YQ

Recent linkage and association studies have implicated the chromosome 12p13 locus as possibly harboring genetic variants predisposed to Alzheimer's disease (AD). We attempted to replicate this association in a Chinese data set comprised of 256 AD cases and 264 age-matched normal controls. A total of...

DRIVER (Chinese)

26

A genetic locus for adolescent idiopathic scoliosis linked to chromosome 19p13.3

Chan, VNY; Fong, GCY; Luk, KDK; Yip, B; Lee, MK; Wong, MS; Lu, DDS; Chan, TK

Adolescent idiopathic scoliosis (AIS) is one of the most common orthopedic disorders, affecting up to 4% of schoolchildren worldwide. We studied seven unrelated multiplex families of southern Chinese descent with AIS, consisting of 25 affected members. A genomewide scan with >400 fluorescent microsa...

DRIVER (Chinese)