Non-Repairable Strand Breaks Induced by 125I Incorporated into Mammalian DNA

Painter, R. B.; Burki, H. J.; Young, B. R.

When 125I is incorporated into Chinese hamster DNA (via 125I-labeled iododeoxyuridine) and the cells are stored at 77°K, the resulting decays of the isotope cause 4 to 5 breaks/single-strand per disintegration. On the average, about 50% of these breaks are repaired. In contrast, under the same condi...

DRIVER (Chinese)