Sample records for 损坏 (damage)
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64

云南稻核心种质孕穗期耐冷性状间的相关性与生态差异 Ecological Difference and Correlation Among Cold Tolerance Traits at the Booting Stage for Core Collection of Rice Landrace in Yunnan, China

ZENG Ya-wen (曾亚文); LI Shen chong(李绅崇); PU Xiao-ying(普晓英); DU Juan(杜娟); YANG Shu ming(杨树明); LIU Kun(刘昆); G-UI Min(桂敏)

以548份云南地方稻核心种质为材料在昆明自然低温平均18℃(冷害)和温室23℃条件下进行了孕穗期耐冷性状间的相关性及其生态差异分析。冷害条件下云南稻核心种质形态性状均与孕穗期耐冷性有关,耐冷指标性状每穗实粒数、穗颈长、每穗秕粒数、穗下节长、花药长及其体积、1~2节长与结实率呈较高的(≥0.549)极显著(n=548,R0.01=0.112)相关;相反,温室条件下仅有每穗实粒数、秕粒数与结实率相关系数较高。冷害条件下云南稻核心种质的每穗实粒数、花药体积、穗下节长、穗颈长与结实率大小在5个稻作区间的变化规律呈现一致性,这种差异既与株高、穗下节长、穗颈长和1~2节长等耐冷性状有关,又与地州或稻区间的...

DRIVER (Chinese)

67

X-ray response of Chinese hamster ovary cells during the latter part of G2.

Griffiths, T D

The ability of Chinese hamster ovary (CHO) cells to repair x-radiation damage during the transit from the late G2 to early M cell cycle stages was investigated by conventional dose-fractionation techniques. Despite their relatively high radiation sensitivity, CHO cells positioned in late G2 exhibit ...

DRIVER (Chinese)

68

The p53 status of Chinese hamster V79 cells frequently used for studies on DNA damage and DNA repair.

Chaung, W; Boorstein, R J; Mi, L J

Chinese hamster lung fibroblast V79 cells have been widely used in studies of DNA damage and DNA repair. Since the p53 gene is involved in normal responses to DNA damage, we have analyzed the molecular genetics and functional status of p53 in V79 cells and primary Chinese hamster embryonic fibroblas...

DRIVER (Chinese)

69

The interaction between semantic and the nonsemantic systems in reading: Evidence from Chinese

Bi, Y; Han, Z; Weekes, B; Shu, H

We report a Chinese-speaking patient WJX with left temporal lobe ischemic damage resulting in dementia. Similar to English speaking patients with this pathology, WJX showed impaired semantic system functioning together with a well preserved ability to read aloud Chinese characters including characte...

DRIVER (Chinese)

72

THE ROLE OF INHIBITORS OF POLY(ADP-RIBOSE) POLYMERASE AS RESISTANCE-MODIFYING AGENTS IN CANCER-THERAPY

GRIFFIN, RJ; CURTIN, NJ; NEWELL, DR; GOLDING, BT; DURKACZ, BW; CALVERT, AH

Poly(ADP-ribose) polymerase (PARP) plays an important role in a number of cellular processes including DNA repair. Since poly(ADP-ribosyl)ation occurs in response to radiation- or drug-induced DNA damage, inhibitors of the enzyme may enhance the antitumour activity of radiotherapy or cytotoxic drug ...

DRIVER (Chinese)

76

Segregation of DNA polynucleotide strands into sister chromatids and the use of endoreduplicated cells to track sister chromatid exchanges induced by crosslinks, alkylations, or x-ray damage.

Wolff, S; Afzal, V

The method of Matsumoto and Ohta [Matsumoto, K. & Ohta, T. (1992) Chromosoma 102, 60-65; Matsumoto, K. & Ohta, T. (1995) Mutat. Res. 326, 93-98] to induce large numbers of endoreduplicated Chinese hamster ovary cells has now been coupled with the fluorescence-plus-Giemsa method of Perry and ...

DRIVER (Chinese)

78

Role of the human ERCC-1 gene in gene-specific repair of cisplatin-induced DNA damage.

Larminat, F; Bohr, V A

The human excision repair gene ERCC-1 gene restores normal resistance to UV and mitomycin C in excision repair deficient chinese hamster ovary cells of complementation group 1. To investigate the involvement of the ERCC-1 gene in gene-specific repair of bulky lesions, we have studied the removal of ...

DRIVER (Chinese)

82

Repair-deficient xeroderma pigmentosum cells made UV light resistant by fusion with X-ray-inactivated Chinese hamster cells.

Karentz, D; Cleaver, J E

Xeroderma pigmentosum (XP) is an autosomal recessive human disease, characterized by an extreme sensitivity to sunlight, caused by the inability of cells to repair UV light-induced damage to DNA. Cell fusion was used to transfer fragments of Chinese hamster ovary (CHO) chromosomes into XP cells. The...

DRIVER (Chinese)

84

Proceedings of the third Asia-Pacific Symposium on Wind Engineering: December 13-15, 1993, Hong Kong

Cheung, Yau Kai; Lam, K. M.

v.1 Foreword Cheung, Y.K. Cheung, Y.K. v.1 Acknowledgement v.1 Scientific advisory board v.1 Organizing committee v.1 Author index v.2 tForeword Cheung, Y.K. Cheung, Y.K. v.2 Acknowledgement v.2 Scientific advisory board v.2 Organizing committee v.2 Author index v.1 Keynote papers v.2 Wind environment assessme...

DRIVER (Chinese)

86

Persistent DNA damage inhibits S-phase and G2 progression, and results in apoptosis.

Orren, D K; Bohr, V A; Petersen, L N

We used genetically related Chinese hamster ovary cell lines proficient or deficient in DNA repair to determine the direct role of UV-induced DNA photoproducts in inhibition of DNA replication and in induction of G2 arrest and apoptosis. UV irradiation of S-phase-synchronized cells causes delays in ...

DRIVER (Chinese)

88

On Microvascular Inflammation and Intestinal Leakage in Radiation Enteropathy

Röme, Andrada

Gastrointestinal tract damage is an insidious feature in patients undergoing radiotherapy. Microvascular inflammation, including leukocyte and platelet recruitment as well as epithelial barrier dysfunction, are considered to constitute key components in the pathophysiology of radiation-induced enter...

DRIVER (Chinese)

90

Nucleotide Excision repair pathway modulating both cancer risk and therapy

Abbasi, Rashda

Nukleotid Exzisions Reparatur (NER) spielt eine wichtige Rolle bei der Reparatur vieler verschiedener Arten von DNA-Schäden, dazu gehören auch DNA-Addukte, die durch ultraviolette Strahlung und durch Exposition gegenüber schädlichen Substanzen wie Tabakrauch und Alkohol entstehen. Genetische Variati...

DRIVER (Chinese)

91

Non-semantic reading and writing routes in Chinese evidence from a Cantonese- speaking brain injured patient

Or, Wing-yee, Bella; 柯穎儀

"A dissertation submitted in partial fulfilment of the requirements for the Bachelor of Science (Speech and Hearing Sciences), The University of Hong Kong, May 10, 2000." Also available in print. Thesis (B.Sc)--University of Hong Kong, 2000

DRIVER (Chinese)

97

Managed floats to damp shocks like 1982-5 and 2006-9: Field and laboratory Evidence for Chinese interest in a single world currency

Pope, Robin; Selten, Reinhard; Kube, Sebastian; Hagen, Jürgen von

This paper's field evidence is: (1) many official sectors rapidly forget the damage of the 1982-85 exchange rate liquidity crisis and reverted to what caused that crisis, namely a closed economy clean floats perspective; and (2) the 2006-2008/9 exchange rate liquidity shock would have been more dras...

DRIVER (Chinese)

100

Lymphocyte DNA damage in cigarette factory workers measured by comet assay (Chinese)

Lu, X; Zhu, CQ; Wei, BX; Liu, WW; Lao, X; Chen, YH; Xu, QR; 黨, 衛民; Lam, TH; Jiang, CQ

DRIVER (Chinese)

103

Laser-UV-microirradiation of interphase nuclei and posttreatment with caffeine: a new approach to establish the arrangement of interphase chromosomes

Zorn, Christian; Cremer, Thomas; Cremer, Christoph; Zimmer, J.

Laser UV microirradiation of Chinese hamster interphase cells combined with caffeine post-treatment produced different patterns of chromosome damage in mitosis following irradiation of a small area of the nucleus that may be classified in three categories: I) intact metaphase figures, II) chromosome...

DRIVER (Chinese)

104

Induction of internucleosomal DNA fragmentation by carcinogenic chromate: relationship to DNA damage, genotoxicity, and inhibition of macromolecular synthesis.

Xu, J; Manning, F C; Wise, J P; Blankenship, L J; Bridgewater, L C; Patierno, S R

Hexavalent chromium (Cr) compounds are respiratory carcinogens in humans and animals. Treatment of Chinese hamster ovary cells with 150 and 300 microM sodium chromate (Na2CrO4) for 2 hr decreased colony-forming efficiency by 46 and 92%, respectively. These treatments induced dose-dependent internucl...

DRIVER (Chinese)

105

Induction of chromosome damage by ultraviolet light and caffeine: Correlation of cytogenetic evaluation and flow karyotype

Cremer, Christoph; Cremer, Thomas; Gray, J. W.

Asynchrononously growing cells of a M3-1 Chinese hamster line were ultraviolet (UV) irradiated ( = 254 nm) with UV fluences up to 7.5 J/m2. After irradiation, cells were incubated with or without 2 mM caffeine for 20 hr, then mitotic cells were selected by mechanical shaking. Their chromosomes were ...

DRIVER (Chinese)

106

Induction of beta-polymerase mRNA by DNA-damaging agents in Chinese hamster ovary cells.

Wilson, S H; Fornace, A J; Hollander, M C; Zmudzka, B

Only a few of the genes involved in DNA repair in mammalian cells have been isolated, and induction of a DNA repair gene in response to DNA damage has not yet been established. DNA polymerase beta (beta-polymerase) appears to have a synthetic role in DNA repair after certain types of DNA damage. Her...

DRIVER (Chinese)

107

Induction of Thioguanine- and Ouabain-Resistant Mutants and Single-Strand Breaks in the DNA of Chinese Hamster Ovary Cells by 3H-Thymidine

Cleaver, James E.

Cultured Chinese hamster cells were labeled with 6-3H-thymidine or 5-methyl-3H-thymidine and allowed to accumulate damage from 3H decays for various periods of time while frozen. The frequencies of cells resistant to 6-thioguanine or ouabain and the amount of DNA damage (i.e., number of single-stran...

DRIVER (Chinese)

108

Inducible expression and cytogenetic effects of the EcoRI restriction endonuclease in Chinese hamster ovary cells.

Winegar, R A; Morgan, W F; Land, M C; Fero, M L

The cytogenetic endpoints sister chromatid exchange (SCE) and chromosome aberrations are widely used as indicators of DNA damage induced by mutagenic carcinogens. Chromosome aberrations appear to result directly from DNA double-strand breaks, but the lesion(s) giving rise to SCE formation remains un...

DRIVER (Chinese)

110

Human chromosome 5 complements the DNA double-strand break-repair deficiency and gamma-ray sensitivity of the XR-1 hamster variant.

Mirman, D; Giaccia, A J; MacLaren, R; Denko, N; Waldren, C; Hart, I; Stamato, T D

XR-1 is a Chinese hamster ovary (CHO) cell mutant which is unusually sensitive to killing by gamma rays in the G1 portion of the cell cycle but has nearly normal resistance to gamma-ray damage in late S phase. The cell-cycle sensitivity correlates with the mutant's inability to repair DNA double-str...

DRIVER (Chinese)

111

Galectin binding proteins in serum and bronchoalveolar lavage -in healthy and pathological conditions

Cederfur, Cecilia

Galectins are carbohydrate binding proteins, implicated in conditions of both inflammation and cancer. Connections between chronic inflammation and cancer are proposed by the increased remodelling and proliferation that occurs, leading to enhanced survival and proliferation of malignant cells. Since...

DRIVER (Chinese)

112

Expression of c-fos and oxidative stress on brain of rats reared on food from mercury-selenium coexisting mining area Expression of c-fos and oxidative stress on brain of rats reared on food from mercury-selenium coexisting mining area

CHENG;Jin-ping;HU;Wei-xuan;LIU;Xiao-jie;ZHENG;Min;SHI;Wei;WANG;Wen-hua(CHENG)

Foundation item: The National Basic Research Program (973) of China (No. 2003CB415003); the Chinese Academy of Sciences for Key and Innovation Projects (No. KZCX3-SW-437) and the National Natural Science Foundation of China (No. 20277007; 40303013);

DRIVER (Chinese)

114

Effects of vitamins on chromium(VI)-induced damage.

Sugiyama, M

The effects of vitamin E and vitamin B2 on DNA damage and cellular reduction of chromium(VI) were investigated using Chinese hamster V-79 cells. Pretreatment with alpha-tocopherol succinate (vitamin E) resulted in a decrease of DNA single-strand breaks produced by Na2CrO4, while similar treatment wi...

DRIVER (Chinese)

115

Effects of genomic context and chromatin structure on transcription-coupled and global genomic repair in mammalian cells

Tang, Moon-shong; Feng, Zhaohui; Chasin, Lawrence A.; Hu, Wenwei

It has been long recognized that in mammalian cells, DNA damage is preferentially repaired in the transcribed strand of transcriptionally active genes. However, recently, we found that in Chinese hamster ovary (CHO) cells, UV-induced cyclobutane pyrimidine dimers (CPDs) are preferentially repaired i...

DRIVER (Chinese)

116

Dielectric coatings for optimized low-loss saturable absorbers for high-power ultrafast laser

Zhang, Liang; König, Farina; Neuhaus, Jörg; Bauer, Dominik; Dekorsy, Thomas; Chen, Yafu

With the development of high power ultrafast laser passively mode-locked by a semiconductor saturable absorber mirror (SESAM), the damage threshold and degeneration mechanism of the SESAM become more and more important. One way to reduce the maximulIl electric field inside the active part of the SES...

DRIVER (Chinese)

118

Damage and Repair of DNA in 5-Bromodeoxyuridine-Labeled Chinese Hamster Cells Exposed to Fluorescent Light

Ben-Hur, E.; Elkind, M. M.

Illumination of Chinese hamster cells with fluorescent light after 5-bromodeoxyuridine incorporation leads to extensive single-strand breakage in the DNA of the exposed cells. The rate of production of single-strand breaks is dependent on the extent to which thymine is replaced by 5-bromouracil. At ...

DRIVER (Chinese)

120

DNA repair in the metallothionein gene increases with transcriptional activation.

Okumoto, D S; Bohr, V A

We have studied DNA repair in the Chinese Hamster Ovary (CHO) metallothionein (MT) gene after UV-light induced damage. The repair was examined comparatively with or without transcriptional activation of the gene by incubation in the presence of the heavy metal ZnCl2. Whereas the repair efficiency wa...

DRIVER (Chinese)

121

DNA damage-inducible transcripts in mammalian cells.

Fornace, A J; Hollander, M C; Alamo, I

Hybridization subtraction at low ratios of RNA to cDNA was used to enrich for the cDNA of transcripts increased in Chinese hamster cells after UV irradiation. Forty-nine different cDNA clones were isolated. Most coded for nonabundant transcripts rapidly induced 2- to 10-fold after UV irradiation. On...

DRIVER (Chinese)

124

Clinical characteristics and outcome of southern Chinese males with systemic lupus erythematosus

Mok, CC; Lau, CS; Chan, TM; Wong, RWS

The aims were to study the gender differences in clinical manifestations, disease course and organ damage in systemic lupus erythematosus (SLE). Clinical manifestations, autoantibody profile, relapses and damage scores were obtained from 51 Chinese males with SLE and compared with 201 consecutive fe...

DRIVER (Chinese)

125

Civil Liability for Marine Oil Pollution Damage: A comparative and economic study of the international, US and the Chinese compensation regime

Wang, H.

Oil resources are unevenly distributed on the earth and most oil needs to be transported by sea.Therefore, ocean transport of oil is largely a one-way trade from the principal supply areas to theoil consuming states. The main routes of crude oil shipping are from the Middle East andSoutheast Asia...

DRIVER (Chinese)

127

Cell Proliferation and DNA Breaks Are Involved in Ultraviolet Light-induced Apoptosis in Nucleotide Excision Repair-deficient Chinese Hamster Cells

Dunkern, Torsten R.; Kaina, Bernd

UV light targets both membrane receptors and nuclear DNA, thus evoking signals triggering apoptosis. Although receptor-mediated apoptosis has been extensively investigated, the role of DNA damage in apoptosis is less clear. To analyze the importance of DNA damage induced by UV-C light in apoptosis, ...

DRIVER (Chinese)

128

CPD sessions: shipping law - an overview


[Programme] Shipping law: an overview Registration and classification Captain Ajay Hazari Hazari, Ajay Introduction to shipping law Alastair MacAulay MacAulay, Alastair Shipping law: an overview Andrew Williams Williams, Andrew Shipping law: an overview Fung King Tak Fung, King-tak Booking orders, bills...

DRIVER (Chinese)

134

Assessment of the significance of mitochondrial DNA damage by chemotherapeutic agents

Lo, S; Tolner, B; Taanman, JW; Cooper, JM; Gu, M; Hartley, JA; Schapira, AHV; Hochhauser, D

The pathways which are activated following damage to nuclear DNA in cancer cells are well understood. There is evidence that treatment with several chemotherapeutic agents may result in damage to mitochondrial DNA. This study investigated the contribution of mitochondrial DNA to cytotoxicity of DNA-...

DRIVER (Chinese)

136

A study on lymphocyte DNA damage in traffic policemen in Guangzhou (Chinese) 广州市交通警察淋巴细胞DNA 损伤的研究

Zhu, CQ; Lam, TH; Jiang, CQ; Wei, BX; Chen, YH; Xu, QR

OBJECTIVE: To study the effect of occupational exposure to traffic exhaust and smoking on DNA damage in traffic policemen. METHODS: 812 traffic policemen (741 men and 71 women, 130 of office-work and 682 of outside work) from 8 districts in Guangzhou were investigated. Blood samples were taken by ve...

DRIVER (Chinese)

137

A p53-independent damage-sensing mechanism that functions as a checkpoint at the G1/S transition in Chinese hamster ovary cells

Lee, Hoyun; Hamlin, Joyce L.; Larner, James M.

In response to a moderate dose of radiation, asynchronous mammalian cell populations rapidly and transiently down-regulate the rate of DNA synthesis to ≈50% of preirradiation values. We show here that only half of the reduction in overall replication rate can be accounted for by direct inhibition of...

DRIVER (Chinese)

138

A novel DNA damage-inducible transcript, gadd7, inhibits cell growth, but lacks a protein product.

Hollander, M C; Fornace, A J; Alamo, I

gadd7 cDNA was isolated from Chinese hamster ovary (CHO) cells on the basis of increased levels of RNA following treatment with UV radiation. The transcript for gadd7, as well as for four other gadd genes, was found to increase rapidly and coordinately following several different types of DNA damage...

DRIVER (Chinese)

139

A linear-quadratic model of cell survival considering both sublethal and potentially lethal radiation damage Un modèle linéaire-quadratique de la survie cellulaire considérant à la fois sublétale et potentiellement mortelle d'irradiation dégâts

Coucke, Philippe; Rutz; Mirimanoff

We assessed the dose-dependence of repair of potentially lethal damage in Chinese hamster ovary cells x-irradiated in vitro. The recovery ratio (RR) by which survival (SF) of the irradiated cells was enhanced increased exponentially with a linear and a quadratic component, namely xi and psi: RR = e ...

DRIVER (Chinese)

141

Zhu, Changqi; 朱昌淇

DRIVER (Chinese)

142

Man, Wai-kwong; 文偉光

DRIVER (Chinese)