Sample records for C层 (c region)

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Inducible overproduction of the mouse c-myc protein in mammalian cells.

Wurm, F M; Kingston, R E; Gwinn, K A

We have made Chinese hamster ovary (CHO) cell lines that contain up to 2000 copies of the coding region of the mouse c-myc gene fused to the promoter of the Drosophila gene (hsp70) encoding a Mr 70,000 heat shock protein. Incubation of these cells at 43 degrees C results in an estimated 100-fold ind...

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Economic development in Chinese societies : models and experiences

List of editors and contributors pvii Acknowledgement pix Ch.1 Introduction / Jao, Y.C. p1 Pt.I General perspectives p7 Pt.II Economic development and reforms in mainland China p37 Pt.III The NIC development models p141 Pt.IV Special topics p233 Ch.2 A comparative analysis of economic development experienc...

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Effectiveness of the de-orbiting practices in the MEO region

Rossi A.; Anselmo L.; Pardini C.; Jehn R.

The Medium Earth Orbit (MEO) region is becoming increasingly exploited as the number of navigation constellations grows with the advent of the European GALILEO and the Chinese COMPASS systems. There is the need for an effective disposal strategy of satellites at end-of- life able to prevent any poss...

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Fine mapping of the 9q31 Hirschsprung’s disease locus

Tang, S. C.; Sribudiani, Y.; Miao, P. X.; Vries, R. A.; Burzynski, G.; So, T. M.; Leon, Y. Y.; Yip, H. B.; Osinga, J.

Hirschsprung’s disease (HSCR) is a congenital disorder characterised by the absence of ganglia along variable lengths of the intestine. The RET gene is the major HSCR gene. Reduced penetrance of RET mutations and phenotypic variability suggest the involvement of additional modifying genes in the dis...

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Behavioural, emotional and family functioning of hospitalized children in China and Hong Kong

Kennedy, C; Kools, S; Kong, SK; Chen, JL; Franck, L; Wong, TK

PURPOSE: This study examined behavioural and emotional problems, social competence and family functioning of hospitalized Chinese children in Hong Kong and the Chinese Mainland. METHOD: A sample of 210 hospitalized children (ages 2-11 years) and their families participated in the study. The families...

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Dose-dependent differences in the profile of mutations induced by an ultimate carcinogen from benzo[a]pyrene.

Jerina, D M; Yagi, H; Bhachech, N; Wei, S J; Preston, B D; Wong, C Q; Chang, R L; Cui, X X; Sayer, J M; Hennig, E

Mutations in the coding region of the hypoxanthine (guanine) phosphoribosyltransferase (HPRT) gene of Chinese hamster V-79 cells were examined after exposure of the cells to a high cytotoxic dose (0.48 microM; 35% survival) and a low noncytotoxic dose (0.04 microM; 100% survival) of the ultimate car...

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Methotrexate-resistant Chinese hamster ovary cells have amplified a 135-kilobase-pair region that includes the dihydrofolate reductase gene.

Rothman, S M; Milbrandt, J D; White, W C; Heintz, N H; Hamlin, J L

For the eventual purpose of isolating and studying a single animal cell replicon, we have developed a methotrexate-resistant Chinese hamster ovary cell line that has amplified an early-replicating DNA sequence approximately 500 times; this sequence includes the gene coding for dihydrofolate reductas...

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Association of GAD-65, but not of GAD-67, with the Golgi complex of transfected Chinese hamster ovary cells mediated by the N-terminal region.

Dirkx, R; Solimena, M; Muntzel, C; Aggujaro, D; Butler, M; De Camilli, P; Hayday, A

Glutamic acid decarboxylase (GAD) is the enzyme responsible for synthesis of the neurotransmitter gamma-aminobutyric acid in neurons and pancreatic beta cells. It is represented by two isoforms, GAD-65 and GAD-67, which are the products of two different genes and differ substantially only at their N...

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Impact du changement climatique sur la productivité forestière et le déplacement d'une limite bioclimatique en région méditerranéenne française

Vennetier, M.; Vila, B.; Liang, E.Y.; Guibal, F.; Ripert, C.; Chandioux, O.

This paper presents the methodological approach used for the study of the impact of climate change on the productivity of Mediterranean forests and the shift of the bioclimatic limit between Pinus halepensis and Pinus silvestris. It also gives some of the main synthetic results of this research, bas...

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An ancient balanced polymorphism in a regulatory region of human major histocompatibility complex is retained in Chinese minorities but lost worldwide

Liu, X; Fu, Y; Liu, Z; Lin, B; Xie, Y; Liu, Y; Xu, Y; Lin, J; Fan, X; Dong, M; Zeng, K; Wu, C-I; Xu, A

The coding regions of many of the major histocompatibility complex (MHC) (human leukocyte antigen [HLA] in humans) molecules are believed to be subject to balancing selection. But it is less certain whether the regulatory regions of such coding sequences are also subject to the same type of selectio...

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beta-Thalassemia in Chinese: use of in vivo RNA analysis and oligonucleotide hybridization in systematic characterization of molecular defects.

Kazazian, H H; Potter, M J; Cheng, T C; Antonarakis, S E; Orkin, S H; Sexton, J P; Li, A; Markham, A F; Giardina, P J

To perform a systematic analysis of beta-thalassemia genes among Chinese, we have determined the DNA haplotype in the beta-globin gene region of 37 Chinese beta-thalassemia chromosomes. Only four haplotypes were found. Blot hybridization analysis of erythroid RNA from patients homozygous for haploty...

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The utility of screening for perinatal depression in the second trimester among Chinese: a three-wave prospective longitudinal study

Lau, Ying; Wong, Keung Fu Daniel; Chan, Sin Kin

This paper aims to study the pattern of perinatal depressive symptomatology and determine the predictive power of second trimester perinatal depressive symptoms for future perinatal periods. A population-based sample of 2,178 women completed the Edinburgh Postnatal Depression Scale (EPDS) in the sec...

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TNFalpha-Polymorphismus bei Patienten mit Sepsis und Schilddrüsenkarzinomen

Rossbach, Christiane

Das Zytokin Tumornekrosefaktor a (TNFa) hat einen entscheidenden Anteil an der Entwicklung schwerer Komplikationen, wie septischer Schock und Multiorganversagen nach Entwicklung einer Sepsis. Eine Assoziation des TNF2-Allels mit einem erhöhten TNF a Spiegel und einer höheren Mortalitätsrate wurde i...

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The influence of the guanidine to adenine (G/A) substitution in the promoter region of the apolipoprotein (apo) AI gene (at -75 bp) on serum lipids and apolipoproteins was studied in 287 healthy Chinese of both sexes in Singapore. Women had significantly higher levels of high-density lipoprotein cho...

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Education and competitive economy: how do cultural dimensions fit in?

Cheung, Yan Hoi; Chan, Ho Wing Alex

Globalization has changed the way people behave in different aspects of life. One of the significant differences is that people are now competing with everyone around the world, not just people within or near their own regions. A good way of remaining competitive is to provide quality education that...

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Bone turnover markers and prediction of bone loss in elderly women

Lenora, Janaka

Around 70,000 osteoporosis-related fractures occur in Sweden annually and approximately half of the women in western world will sustain a fragility fracture after the age of 50 years. Fracture preventive efforts require the identification of individuals who are at high risk. Biochemical markers of b...

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