Selecting men for bone densitometry: performance of osteoporosis risk assessment tools in Portuguese men

Machado, P; Coutinho, M; Pereira da Silva, JA

Clinicians need tools to identify patients most likely to benefit from bone mineral density (BMD) testing, for which cost-effectiveness does not allow generalized screening. This study supports the utility of osteoporosis risk assessment tools in selecting men for BMD testing. Different cutoff value...

DRIVER (Portuguese)

Genomewide Linkage Analysis of Bipolar Disorder by Use of a High-Density Single-Nucleotide–Polymorphism (SNP) Genotyping Assay: A Comparison with Microsatellite Marker Assays and Finding of Significant Linkage to Chromosome 6q22

Kirby, A. N.; Petryshen, T. L.; Coelho, I.; Kennedy, J. L.; Brown, A.; Sklar, P.; Medeiros, H.; Macedo, A.; Gentile, K. L.

We performed a linkage analysis on 25 extended multiplex Portuguese families segregating for bipolar disorder, by use of a high-density single-nucleotide–polymorphism (SNP) genotyping assay, the GeneChip Human Mapping 10K Array (HMA10K). Of these families, 12 were used for a direct comparison of the...

DRIVER (Portuguese)

Desempenho de algoritmos de avaliação do risco osteoporótico em mulheres pós-menopáusicas portuguesas Performance of decision algorithms for the identification of low bone mineral density in portuguese postmenopausal women

Machado, P; Pereira da Silva, JA

OBJECTIVES: Although several algorithms have been proposed to select postmenopausal women PMW for dual-energy x-ray absorptiometry DEXA measurements information on their utility in clinical practice is scarce. Our aim was to assess the utility and the economic repercussion of the use of five of thes...

DRIVER (Portuguese)

Bicycle Use for Transport in an Australian and a Belgian City: Associations with Built-Environment Attributes

Owen, Neville; De Bourdeaudhuij, Ilse; Sugiyama, Takemi; Leslie, Eva; Cerin, Ester; Van Dyck, Delfien; Bauman, Adrian

The walkability attributes of neighborhood environments (residential density, land use mixture, and connectedness of streets) have been found to be associated with higher rates of walking. However, relatively less is known about the associations of walkability attributes with bicycle use for transpo...

DRIVER (Portuguese)

Analysis of genetic markers for cardiovascular disorders in a portuguese population with familial hypercholesterolemia

Gomes, Alexandra Paula dos Reis

Familial Hypercholesterolemia (FH) is a genetic disorder that leads to an increase in the levels of total and low density lipoprotein cholesterol promoting atherosclerosis (ATH) and premature cardiovascular disease (CVD). Inflammation has been considered to be involved in the pathogenesis of CVD nam...

DRIVER (Portuguese)