Sample records for CENTROS Z (z centers)
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1

FACTORES LABORALES Y PERSONALES FRENTE A LA OCURRENCIA DE ACCIDENTES DE TRABAJO BIOLÓGICOS EN EL PERSONAL DE ENFERMERÍA DE LA CLÍNICA VILLAPILAR ESE RITA ARANGO ÁLVAREZ DEL PINO MANIZALES (CALDAS) 2005-2006/ WORK AND PERSONAL FACTORS REGARDING BIOLOGICAL WORK ACCIDENTS IN THE NURSING PERSONNEL OF THE VILLAPILAR ESE RITA ARANGO ÁLVAREZ DEL PINO CLINIC, MANIZALES (CALDAS) 2005-2006/ FATORES LABORAIS E PERSONAIS FRENTE Á OCORRÊNCIA DE ACIDENTES DE TRABALHO BIOLOGICOS NO PESSOAL DE ENFERMARIA CLÍNICA VILAPILAR ESE RITA ARANGO ÁLVAREZ DO PINO MANIZALES 2005-2006(CALDAS)

Franco Patiño, Jaqueline; Marín Sánchez, Alexandra; Ocampo Restrepo, Lina María; Quiroz Buchely, Tania Judith; Díaz Obando, Paula Andrea
2007-12-01

Resumen en portugués Os trabalhadores da saúde, especialmente o pessoal de enfermaria, encontram-se expostos a uma importante variedade de fatores de risco laborais e pessoais que podem provocar acidentes de trabalho dependendo do tipo de tarefas que desempenham e o posto de trabalho que ocupam. A Clínica Vilapilar ESSE Rita Arango do Pino de Manizales como instituição de alta complexidade, e a qual tem uma grande demanda por parte da povoação do Estado de Caldas, devido à amplia quant (mas) idade de serviços hospitalarias e especializados que oferece, foi a instituição escolhida para realizar esta investigação. Estudaram-se os fatores laborais e pessoais que incidiam na ocorrência dos acidentes de trabalhos biológicos, assim como a notificação dos mesmos no pessoal de enfermaria tanto auxiliar durante o período de junho a novembro de 2005. Realizou-se um estúdio quantitativo, em onde utilizaram-se como instrumentos para a colheita de informação: uma enquête estruturada de acordo aos parâmetros das normas ANSI-Z-2, revisão documental e uma guia de observação; do análise dos resultados pôde- se concluir que: De 11 acidentes de trabalho notificados, 7 (63%) foram no pessoal de enfermaria. Sendo os mais freqüentes o acidente por punção ao qual se realiza seguimento conforme os protocolos estabelecidos. O 100% da povoação que tenha tido acidentes de trabalho, tem notificado o fato e, destes o 90% considera que os elementos proteção pessoal que proporciona a instituição são suficientes. Os resultados obtidos são similares aos outros centros hospitalarias em onde o risco de punção é o mais freqüente. Esta possibilidade de transmissão de agentes infecciosos por esta via de entrada, destaca-se a importância de desenvolver programas preventivos deste freqüente acidente de trabalho. Resumen en español Los trabajadores de la salud, especialmente el personal de enfermería, se encuentran expuestos a una importante variedad de factores de riesgo laborales y personales que pueden provocar accidentes de trabajo dependiendo del tipo de tareas que desempeñan y el puesto de trabajo que ocupan. La Clínica Villapilar ESE Rita Arango Álvarez del Pino de Manizales como institución de alta complejidad, y la cual tiene una gran demanda por parte de la población del departamento (mas) de Caldas, debido a la amplia cantidad de servicios hospitalarios y especializados que ofrece, fue la institución escogida para realizar esta investigación. Se estudiaron los factores laborales y personales que incidieron en la ocurrencia de accidentes de trabajo biológicos, así como la notificación de los mismos en el personal de enfermería tanto auxiliar como profesional durante el periodo de junio a noviembre de 2005. Se realizó un estudio cuantitativo descriptivo, en donde se utilizaron como instrumentos para la recolección de información: una encuesta estructurada de acuerdo a los parámetros de las normas ANSI-Z-2, revisión documental y una guía de observación; del análisis de los resultados se pudo concluir que: De 11 accidentes de trabajo notificados, 7 (63%) fueron en el personal de enfermería, siendo el más frecuente el accidente por punción, al cual se le realiza seguimiento según los protocolos establecidos. El 100% de la población que ha tenido accidentes de trabajo, ha notificado el hecho y, de éstos, el 90% considera que los elementos de protección personal que proporciona la institución son suficientes. Los resultados obtenidos son similares a los de otros centros hospitalarios en donde el riesgo de punción es el más frecuente. Dada la posibilidad de transmisión de agentes infecciosos por esta vía de entrada, se destaca la importancia de desarrollar programas preventivos de este frecuente accidente laboral (1). Resumen en inglés Health workers, especially nursing personnel, are usually exposed to a large variety of work and personal risk factors that can cause industrial accidents depending on the types of duties they perform. VillaPilar ESE Rita Arango Alvarez del Pino Clinic of Manizales is an institution that develops complex surgeries and procedures. Because of this, its services are highly demanded by the people that live in the Department of Caldas. The clinic offers a wide range of special (mas) ized health services and this was the reason it was chosen to carry out this research process. The work and personal factors that influence the occurrence of biological work factors were studied, as well as the notification of these by professional and assistant nursing personnel from June to November 2005. A descriptive quantitative study was carried out, using the following tools for gathering information: a survey designed according to the regulations established by ANSI-Z-2 norms, document analysis and an observation guide. The conclusions include: from 11 reported work accidents, 7 (63%) happened to nursing personnel. The most frequent accident was puncturing, which is monitored according to the protocol established. 100% of the population that has had work accidents has notified the event, and 90% of them think that the personal protection tools provided by the institution are enough. The results obtained are similar to those of other hospital centers, where puncturing risk is the most frequent. Due to the possibility of transmission of infectious agents by this entry way, it its important to develop prevention programs against this frequent work accident (2).

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2

Aplicación del sistema de costo en el policlínico Héroes del Moncada

Cruz Alvarez, Nélida María; Verdial Vidal, Roberto; Vázquez Vigoa, Alfredo; Gamon Morales, Nuria
1996-06-01

Resumen en español RESUMEN Se analizan los costos unitarios de los centros finales en el policlínico "Héroes del Moncada" en Ciudad de La Habana, en etapas del año 1991 al 1993 mediante la aplicación del sistema aprobado por el Ministerio de Salud Pública cubano. Se realiza un estudio descriptivo de corte transversal. Se comparan los costos de los centros de servicios finales, en especial el costo del modelo de atención comunitaria y el del médico y enfermera de la familia, resultand (mas) o mayor en el primero ($ 3,77 - $ 6,93) en relación con el otro ($ 2,86 - $ 2,63). Se concluye que en el 43 % de los consultorios el costo unitario fue de $ 2,01 a $ 2,50. Se patentizó la posibilidad de aplicar el sistema hasta el grupo básico de trabajo y se valora la importancia de aplicar los sistemas de costos en los niveles de dirección. Resumen en inglés The unitarian costs of the final services centers at the "Heroes del Moncada" policlinic, at Ciudad de La Habana, are analyzed in stages from 1991 to 1993, by means of the application of the system approved by the Cuban Public Health Ministry. A descriptive cross-sectional study is carried out. The cost of final services centers are compared, specially the cost of the communitary care model, and that of the family physician and nurse, being higher in the first (Z 3,77- Z (mas) 6,93) than in the other (Z 2,86 - Z 2,63). It is concluded that in the 43 % of the physicians'offices, the unitarian cost was of Z 2,01 to Z 2,50. The possibility of applying the system up to the basic work group was made evident, and the importance of applying the cost systems at direction levels, is appraised.

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3

Epidemiología de la enfermedad renal crónica no terminal en la población pediátrica española: Proyecto REPIR II/ Epidemiology of chronic kidney disease in Spanish paediatric population: REPIR II Project

Areses Trapote, R.; Sanahuja Ibáñez, M.J.; Navarro, M.
2010-01-01

Resumen en español Objetivo: Describir el funcionamiento del Registro Español Pediátrico de Insuficiencia Renal (REPIR II), dar a conocer la epidemiología de la enfermedad y estudiar aquellos factores que puedan influir en el curso de ésta. Material y métodos: En el REPIR II participan 46 centros distribuidos por toda la geografía española. Para la clasificación y la valoración de la comorbilidad de la enfermedad, hemos utilizado los criterios de las Guías de Práctica Clínica K/ (mas) DOQI. Cada centro aporta, con una periodicidad anual, los datos evolutivos de cada paciente, que quedan registrados en una base de datos on-line. Criterios de inclusión: Pacientes diagnosticados de enfermedad renal crónica (ERC) que se encuentren entre el estadio 2 y 5 en predialisis y con una edad igual o inferior a 18 años. Resultados: En el año 2008 se habían incluido 605 pacientes de 37 centros; la incidencia de la ERC no terminal era de 8,66 por millón de población (ppm) menores 18 años y la prevalencia de 71,06. La patología estructural era la primera causa de ERC (59% de casos). El porcentaje de glomerulopatías fue muy reducido (3%). Había un claro predominio de hombres (66%) y de la raza caucásica (88%). El valor medio del GFR era de 52 ± 2 ml/min/1,73 m², con un 82% de pacientes en estadios 2 y 3. La prevalencia de la anemia era del 30%. Solamente el 19% de nuestros pacientes presentaban HTA y únicamente el 17% de ellos cumplían las cuatro recomendaciones de las Guías K/DOQI sobre el metabolismo calcio-fósforo. El valor medio global del Z-Score de la talla era del -1,03 ± 2. Había 136 pacientes (25%) que tenían un Z-Score de la talla ≤1,88. En un análisis de regresión logística multivariante, sólo se detectó una relación significativa entre la edad y la talla baja. Los menores de 2 años tenían una probabilidad un 40% mayor de tener una talla baja (OR = 1,40; p Resumen en inglés Objective: A national registry of children with Chronic Kidney Disease (CKD) was started in 2007. We analize it to know the incidence, prevalence, demography, etiology, clinical and metabolic state of the children with CKD, in stages 2-5 pre-dialysis, and complying with the K/DOQI guidelines. Material and methods: In the REPIR II 46 centers distributed throughout the Spanish geography are involved. To classify and evaluate comorbidity of the disease, the Clinical Practice (mas) Guidelines K/DOQI criteria are used. Each center provides an annual developmental data of each patient which is recorded in a On-line database. Inclusion criteria: patients with CKD who are between stage 2 and 5 in predialysis and which are 18 years old or less. Results: In 2008 there were 605 patients with CKD, the incidence was 8.66 per million of pediatric population (pmpp) and the prevalence was 71.06 pmpp. Structural anomalies was the primary cause of CKD (59% of the cases). The percentage of glomerular diseases was very low (3%). There was a clear predominance of males (66%) and Caucasian race (88%). Mean GFR was 52 ± 2 ml/min/1.73 m² with 82% of them in stage 2 and 3. The prevalence of anaemia was 30%. Only 19% of our patients had hypertension and only 17% of them fulfilled the 4 recommendations for calcium-phosphorus metabolism of K/DOQI Guidelines. Mean height Z-Score was -1.03 ± 2. There were 136 patients (25%) who had a mean height Z-Score of size

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4

Estado de Conocimiento de los Anfibios de Chile/ Current State of Knowledge about the Amphibians of Chile

Ortiz Z, Juan Carlos; Díaz-Páez, Helen
2006-06-01

Resumen en español Se entrega un resumen histórico del desarrollo de la herpetología en Chile, con una comparación desde la situación entregada por el libro de J.M. Cei en 1962, "Batracios de Chile", hasta la situación actual. Además, se entrega una síntesis de la distribución geográfica de las diferentes especies de anfibios en Chile y se indican aquellas que son compartidas con los países limítrofes. Se dan a conocer las categorías de conservación en que se encuentran las dif (mas) erentes especies, las instituciones donde se guarda el material tipo y los centros de investigación donde se realiza investigación en anfibios en Chile. Finalmente se discute las áreas deficitarias del conocimiento de este taxón Resumen en inglés Trough a historical summary of the herpetology in Chile, this paper reports a comparison among the book of J. M. Cei in 1962 "Batracios de Chile", until the current days. Also, we elaborated a synthesis of the geographical distribution of the different species of amphibians in Chile and we signaled the species shared with the bordering countries. Finally, the conservation categories for the different species, the institutions where the material type is deposited and the a (mas) mphibians research centers presents in Chile are given. Finally, deficit areas of the knowledge of this taxon, are discussed

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5

Trasplante renal en pediatría: una década de experiencia multicéntrica/ Paedriatric renal transplant: a decade of experience

Cano Sch, Francisco; Rosati M, Pía; Pinto S, Viola; Quiero, Ximena; Lagos R, Elizabeth; Delucchi B, Angela; Hevia A, Pilar; Salas del C, Paulina; Rodríguez S, Eugenio; Ramírez P, Katica; María Lillo, Ana
2001-11-01

Resumen en español El trasplante renal en pediatría representa la modalidad óptima de manejo de la insuficiencia renal crónica, ya que permite recuperar en diversos grados las severas complicaciones propias de la uremia, especialmente el retraso del crecimiento. Objetivo: Evaluar los resultados del trasplante renal pediátrico en 3 centros hospitalarios del país, en un período de 10 años (1989-1999). Pacientes y Método: Evaluación retrospectiva de los trasplantes renales en base a u (mas) n protocolo común, efectuados en los hospitales Exequiel González Cortés, Luis Calvo Mackenna y San Juan de Dios, entre julio de 1989 y julio de 1999. Se analizaron 3 grupos de variables: un primer grupo de tipo descriptivo para variables demográficas; un segundo grupo para analizar el crecimiento desde el período de recién nacido hasta el último año de seguimiento, y un tercer grupo que analizó aspectos con relación al trasplante, en especial la inmunosupresión, las complicaciones y la función del injerto por períodos anuales. Las variables continuas fueron expresadas como promedio ± desviación estándar, el crecimiento como puntaje Z, la función renal se graficó como el inverso de creatinina en plasma, y al igual que la evaluación del rechazo agudo en relación al tipo de donante vivo o cadáver, se analizó con la prueba de chi² de Pearson. El análisis de la función renal en relación a los tiempos de isquemia tibia y fría se evaluó por el test t de Student, y la sobrevida a 1, 3 y 5 años para el injerto y pacientes se estudió por la curva de Kaplan Meier. Se consideró significativo un p Resumen en inglés Paedriatric renal transplant is the treatment of choice in chronic renal failure (CRF), in that it permits the recuperation to differing degrees the severe consequences of uraemia, especially in terms of growth retardation. Objective: To evaluate the results of renal transplantation in 3 hospital centers during a 10 year period (1989-99). Patients and Methods: A retrospective study using a standard protocol carried out in the hospitals Exequiel González Cortés, Luis Cal (mas) vo Mackenna and San Juan de Dios between july 1989 and july 1999. 3 types of variables were analyzed; 1) demographic description, 2) growth between birth and the last year of follow-up, and 3) transplant related factors, especially immunosuppression, transplant complications and graft function during annual periods. Continuous variables were expressed as mean + SD, growth as Z score, renal function as 1/plasma creatinine, and together with the analysis of acute rejection in relation to live or cadaveric donor, were analyzed using Pearson´s Chi-squared. Renal function with regards to warm or cold ischaemia was evaluated using Student´s t-test, while Kaplan-Meier curves were used in the analysis of survival at 1,3, and 5 years both for patients and grafts. In all the tests a p value

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6

MICROCRÉDITO EN COLOMBIA

BARONA Z., BERNARDO
2004-03-01

Resumen en español El artículo tiene como propósitos: proporcionar una visión general de la forma en que el financiamiento de los microempresarios y los estratos más vulnerables de la población ha sido abocada en Colombia; resumir los grandes retos que enfrenta en la actualidad el programa de microfinanzas en el mundo, presentar el programa de investigación que están adelantando las Universidades Icesi y del Valle en Colombia en asocio con la Universidad de Laval en Canadá y con alg (mas) unos centros de Investigación de Filipinas, Marruecos y Benin y algunos resultados parciales de este esfuerzo investigativo; y, presentar algunas recomendaciones tendientes a fortalecer a las organizaciones microfinancieras en el país. Una revisión de la historia y el estado actual del microcrédito en Colombia indica que los esfuerzos hasta ahora realizados parecen haberse quedado muy cortos frente a las necesidades de financiación de los microempresarios: la cobertura de microemepresarios alcanzada por instituciones gubernamentales, ONG y la banca convencional ha sido muy baja. En cuanto a los retos que afronta el movimiento microfinanciero en el mundo dos muy importantes son (i), clarificar el efecto de los diferentes esfuerzos de microcrédito realizados en la reducción de la pobreza de la población del país y, (ii), identificar mecanismos para lograr un aumento significativo de la cobertura mediante un balance adecuado entre regulación, supervisión y disciplina de mercado. Los principales resultados (parciales) obtenidos en la línea de investigación descrita en este artículo son (i), contrario a lo que con frecuencia se asume, a medida que una organización cooperativa crece en tamaño no necesariamente se torna más eficiente: los posibles beneficios de la mayor escala fueron más que compensados en las empresas estudiadas por nosotros por la propensión al gasto excesivo que exhiben los gerentes en caso de instituciones de mayor tamaño (ii), las cooperativas rurales colombianas, a pesar de tener un gran potencial para irrigar el crédito en ciertas zonas del país, no parecen estar empleando tecnologías de microcrédito desarrolladas y utilizadas de manera exitosa por instituciones como el Banco Grameen en Bangladesh o la Fundación WWB en Colombia. Resumen en inglés The paper presents a cursory review of the main programs and activities conducted inColombia in the last decades to satisfy the need of financial resources of micro businesses. It also introduces a Research Program that two Colombian Universities have been conducting on the subject of micro credit in association with several universities and research centers of North America, Asia and Africa . The Program‘s main objective is to improve our understanding of the way in whi (mas) ch financial co-operatives operates and, based on this, to put forward recommendations to increase the efficiency of this kind of intermediaries of micro credit, which are particularly important to this sector given their better prospects of being financially sustainable in the long run. A secondary objective of the program is to asses if the credit services provided by financial co-operatives have contributed to reduce poverty. The Research Program is still in progress and the results so far are preliminary. However, our findings suggest that small co-operatives are more efficient than large ones. The potential benefits of economies of scale are overcome by the expense preference behavior of managers of large co-operatives. In addition, financial co-operatives in general have not been using credit assessment and monitoring technologies that have been developed elsewhere and seems more appropriate in dealing with micro enterprises than the technology of credit used by large banks. With respect to the effect of micro credit services provided by co-operatives on poverty reduction our preliminary results indicate that it has not been important, although it has great potential, especially in rural areas.

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7

Ecoendoscopia: Indicaciones de la A a la Z

Gómez, Martín A; Otero R, William; Arbelaez M, Victor; Rodríguez, Jesús
2005-06-01

Resumen en español La ecoendoscopia, ultrasonido endoscópico o endosonografía es un examen que combina las imágenes endoscópicas y ecográficas con el fin de evaluar las lesiones que se encuentran no solo en la pared del tracto gastrointestinal sino también alrededor del mismo. Este examen permite además estadificar los pacientes con cáncer gastrointestinal, tumores del páncreas y de pulmón entre otros. Por lo tanto, las indicaciones de la ecoendoscopia son muy amplias (unas más r (mas) espaldadas por la literatura que otras) y sus utilidades son múltiples, siendo éste un medio diagnóstico utilizado de rutina en muchos centros de gastroenterología en el mundo. La tendencia actual es pasar de la ecoendoscopia diagnóstica a la terapéutica, ya que se está utilizando para múltiples propósitos como guiar cirugías mínimamente invasivas, tomar biopsias a todos los niveles y aplicar terapias biológicas; de éste modo los alcances de este examen son impresionantes. Se realizó una revisión concisa de la literatura para resumir todas las aplicaciones de la ecoendoscopia, con el fin de familiarizar a los gastroenterólogos con sus indicaciones y posibles aplicaciones terapéuticas. Resumen en inglés The echoendoscopy, endoscopic ultrasound or endosonography is an exam which combines the endoscopic and ultrasound images, with the purpose of evaluating the lesions that are not only in the wall of the gastrointestinal tract but also around it. This exam also allows to stadify the patients with gastrointestinal cancer, tumors of the pancreas, lungs, etc. Therefore, the indications of the echoendoscopy are very wide, (some, better supported by the literature than others) (mas) and its purposes multiple, being this a diagnostic tool used as a routine exam in many centers of gastroenterology around the world. The current tendency is to pass from the diagnostic to the therapeutic echoendoscopy since it is being used for multiple purposes, like guiding minimally invasive surgeries, taking biopsies at all levels and for the application of biological therapies; therefore, the usefulness of this exam is really impressive. A concise review of the literature was made to summarize all the applications of the echoendoscopy with the purpose of familiarizing gastroenterologists with the indications and possible therapeutic applications.

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8

LA ADHERENCIA AL TRATAMIENTO NUTRICIONAL Y COMPOSICIÓN CORPORAL: UN ESTUDIO TRANSVERSAL EN PACIENTES CON OBESIDAD O SOBREPESO/ ADHERENCE TO THE NUTRITIONAL TREATMENT AND BODY COMPOSITION: A CROSS-SECTIONAL STUDY IN PATIENTS WITH OBESITY OR OVERWEIGHT

González Z, Laura Inés; Giraldo G, Nubia Amparo; Estrada R, Alejandro; Muñoz R, Alba Luz; Mesa S, Elizabeth; Herrera G, Catalina María
2007-03-01

Resumen en español Se determinó la adherencia al tratamiento nutricional en pacientes con obesidad o sobrepeso y se examinó la relación entre ésta y variables antropométricas, mediante un estudio transversal en 94 sujetos entre 20 y 50 años seleccionados de forma aleatoria en dos centros de atención nutricional de Medellín. La adherencia al tratamiento nutricional se evaluó aplicando un cuestionario, donde puntajes mayores o iguales a 24 se consideraron como adherentes. Además, se (mas) obtuvo información socio-demográfica y antropométrica, previa estandarización de los evaluadores. Se utilizaron medidas descriptivas, prueba de Kolmogorov-Smirnov, Chi-cuadrado para comparación de proporciones, T de Student o U Mann Whitney para comparación de promedios. El 68% de los pacientes fueron clasificados como no adherentes al tratamiento nutricional, encontrando diferencias según actividad física (p=0,013). El peso promedio (p=0,014), Indice de Masa Corporal (p=0,026), perímetro de cintura (p=0,005) y relación cintura cadera (p=0,022), difirieron de acuerdo a la clasificación de adherencia, siendo significativamente más altos en los no adherentes. No hubo diferencias en el porcentaje de masa grasa según adherencia (p=0,690), pero se hallaron al controlar por sexo, p=0,009 mujeres y p=0,026 hombres. La adherencia al tratamiento nutricional en pacientes en dieta para reducir de peso, produce cambios significativos en la composición corporal Resumen en inglés To assess nutritional adherence to treatment among obese or overweight patients and to examine the relationship between anthropometrical variables, 94 subjects between 20-50 years old randomly selected were recruited at two nutritional health centers in Medellin-Colombia. Nutritional adherence to treatment was evaluated using a questionnaire, with a total score above 24 considered as adherent to the treatment. In addition, socio-demographic information was obtained and an (mas) thropometrical variables were measured. We used descriptive statistical, Kolmogorov-Smirnov test, Chi-square for proportions comparison, and Student T test or U Mann Whitney for means comparison. A 68% of the patients were classified as no adherent to the nutritional treatment, with significant differences found according to physical activity (p= 0,013). Mean weight (p= 0,014), BMI (p= 0,026), waist circumference (p= 0,005) and waist-hip ratio (p= 0,022) differed according to adherence, being significantly higher in non adherent patients. Percent body fat did not change by degree of adherence. However when controls were separated by gender the results were significant for both men and women. Nutritional adherence to treatment in patients on a diet for weight reduction produces significant changes in body composition

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mRNA from NCB-20 cells encodes the N-methyl-D-aspartate/phencyclidine receptor: a Xenopus oocyte expression study

Lerma Gómez, Juan; Kushner, Leslie; Spray, David C.; Bennet, Michael V.; Zukin, R. Suzanne
1989-03-01

Digital.CSIC (Spain)

10

Valor pronóstico del nuevo sistema de etapificación internacional en mieloma múltiple: Comparación con el sistema de Durie-Salmon/ Prognostic value of the new international staging system in multiple myeloma: Comparison with Durie-Salmon staging system

Conté L, Guillermo; Figueroa M, Gastón; Lois V, Vivianne; Cabrera C, María Elena; León R, Alvaro; García L, Hernán; Rojas R, Hernán
2008-01-01

Resumen en inglés Background: Since 1975, the Durie-Salmon staging system (D&S) has been a widely accepted prognostic classification of multiple myeloma (MM) patients. Recently, the new International Staging System (ISS) was developed using only the values of albumin and betaZ-microglobulin. Aim: To compare survival of patients with MM treated in six medical centers in Chile according to the D&S system and the new ISS. Material and methods: Retrospective analysis of demographic information (mas) , clinical features and survival rate of patients treated between 1998 and 2002, and grouped according to both systems. Results: Information of 81 patients aged 38 to 90 years (43 women) was retrieved. According D&S system 11% were in stage I 12% in stage II and 73% in stage III According to ISS, 34% were in stage I 35% in stage II and 31% in stage III Median of survival of all patients was 32 months. Both staging systems had a prognostic value. However, median survival for the three stages of the ISS system was significantly different (67, 29 and 14 months in stages III and III, respectively, p =0.02). Patients in advanced stages II and III of the ISS, had a higher frequency of anemia, hypercalcemia, renal failure and hypoalbuminemia. In stages II and III of ISS the presence of renal failure was associated with a non significantly different lower survival. Conclusions: The ISS is a simple and effective grouping method for patients with MM, that predicts survival. The presence of renal insufficiency might identify a subgroup of patients included in stages II and III of ISS with a higher mortality (Rev Méd Chile 2008; 136: 7-12)

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11

Use of constrained synthetic amino acids in β-Helix proteins for conformational control

Zanuy, David; Jiménez, Ana I.; Cativiela, Carlos; Nussinov, Ruth; Alemán, Carlos
2007-03-01

Digital.CSIC (Spain)

12

Trasplante hepático en adultos: casuística de Clínica Alemana de Santiago/ Adult liver transplantation: A single-center experience from Chile

Hepp K, Juan; Ríos R, Horacio; Suárez P, Leopoldo; Zaror Z, Mónica; Quiroga G, Marta; Rodríguez M, Gabriela; Valderrama L, Rodrigo; Humeres A, Roberto; Innocenti C, Franco; Sanhueza, Edgar; Zapata L, Rodrigo; Cárdenas S, Rubén; Palacios J, José M; Abarca Z, Juan; Montalván R, Carlos; Noriega R, Luis M; Videla T, Domingo; Reynolds H, Enrique; Espinoza A, Ricardo; Sandoval S, Renato; Rius A, Montserrat
2002-07-01

Resumen en inglés Background: The success of orthotopic liver transplantation (OLT) has resulted in its widespread use for different liver diseases. Aim: To report our 8 years experience with adult OLT at Clinica Alemana de Santiago. Patients and methods: In all transplantations done at the center, we recorded patient's overall data and survival, postoperative medical and surgical complications and causes of death. Results: Between November 1993 and September 2001, 51 consecutive OLT were (mas) performed in 44 patients (22 females, median age 45 years old). Thirty eight patients presented with chronic and 6 with acute or sub-acute liver failure. Cryptogenic cirrhosis and hepatitis C infection were the most common causes for OLT. Postoperative bleeding and extra-hepatic biliary complications were seen in 17.6 and 21.5% of cases respectively. Acute rejection, bacterial infections, CMV infection or disease and post OLT hemodialysis were the most common medical complications (51, 31, 19.6 and 19.6% of cases respectively). The overall 1 and 5 years survival rates were 80% and 73% respectively. Considering exclusively the last 22 OLT performed since January 1999, the 1 year survival rate has improved to 91%. Conclusions: Liver transplantation in Chile provides a good long term survival with acceptable morbidity, due to a multidisciplinary approach management. The survival rates have improved over the last few years probably due to better surgical techniques, ICU care and immunosuppression. These overall results are comparable with those from other Centers in developed countries (Rev Méd Chile 2002; 130: 779-86)

Scientific Electronic Library Online (Spanish)

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The structure and function of the LH2 (B800–850) complex from the purple photosynthetic bacterium Rhodopseudomonas acidophila strain 10050

Cogdell, Richard J.; Isaacs, Neil W.; Freer, Andy A.; Arellano, Juan B.; Howard, Tina D.; Papiz, Miroslav Z.; Hawthornthwaite-Lawless, Anna; Prince, Stephen
1997-01-01

Digital.CSIC (Spain)

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Synthesis and Crystal Structure of Ba6Cu12Fe13S27

Llanos, Jaime; Mujica, Carlos; Wittke, Oscar; Gómez-Romero, P.; Ramírez, Rafael
1997-01-01

Digital.CSIC (Spain)

15

Studying the underlying event in Drell-Yan and high transverse momentum jet production at the Tevatron

CDF Collaboration; Cabrera, Susana; Cuenca Almenar, Cristóbal; Álvarez González, B.; Casal, Bruno; Cuevas, Javier; Gómez, G.; Rodrigo, Teresa; Ruiz, Alberto; Scodellaro, Luca; Vila, Iván; Vilar, Rocío; Aaltonen, T.
2010-08-02

Digital.CSIC (Spain)

16

Structure refinement of samarium monothio oxide

Llanos, Jaime; Mujica, Carlos; Henríquez, Alicia; Gómez-Romero, P.; Molins Grau, Elíes
2001-03-02

Digital.CSIC (Spain)

17

Serologic Cross-Reactivity between Anaplasma marginale and Anaplasma phagocytophilum

Dreher, U. M.; Fuente García, José de la; Hofmann-Lehmann, R.; Meli, Marina L.; Pusterla, N.; Kocan, Katherine M.; Woldehiwet, Z.; Braun, U.; Regula, G.; Staerk, K. D. C.; Lutz, H.
2005-10-01

Digital.CSIC (Spain)

18

Semileptonic decays of light quarks beyond the Standard Model

González-Alonso, Martín; Jenkins, James P.; Cirigliano, Vincenzo
2010-05-01

Digital.CSIC (Spain)

19

Search for the Z(4430)(-) at BABAR

Babar Collaboration; Azzolini, Virginia; López-March, Neus; Martínez-Vidal, Fernando; Milanés, Diego A.; Oyanguren, Arantza; Aubert, B.
2009-06-01

Digital.CSIC (Spain)

20

Search for hadronic decays of W and Z bosons in photon events in p(p)over-bar collisions at root s=1.96 TeV

CDF Collaboration; Cabrera, Susana; Cuenca Almenar, Cristóbal; Álvarez González, B.; Casal, Bruno; Cuevas, Javier; Gómez, G.; Rodrigo, Teresa; Ruiz, Alberto; Scodellaro, Luca; Vila, Iván; Vilar, Rocío; Aaltonen, T.
2009-09-28

Digital.CSIC (Spain)

21

Resultados de un programa multidisciplinario de tratamiento intensificado de la Diabetes Mellitus tipo 1 (DM1) en un Hospital Público/ Results of a multidisciplinary and intensified treatment program for type 1 Diabetes Mellitus in a Chilean Public Hospital

Codner D, Ethel; Mericq G, Verónica; García B, Hernán; López G, Claudia; Cáceres V, Jeannette; Gaete V, Ximena; Avila A, Alejandra
2003-08-01

Resumen en inglés During the last decade, the importance of glycemic control in the prevention of the microvascular complications of type 1 Diabetes Mellitus (DM1) was clearly demonstrated. Aim: To evaluate the metabolic and anthropometric results of a multidisciplinary intensified treatment program of DMI in children and adolescents. Patients and methods: Report of 54 patients treated during 2001. The intensified treatment consisted of: multiple daily doses of insulin, frequent glycemic c (mas) ontrol, nutritional, psychological and educational support, and permanent availability of a diabetes nurse for telephonic support. Results: Thirty one patients were female, their mean age was 10.4±0.5 years old and 52% were experiencing puberty. Fifty three percent of the patients used 3 insulin doses per day, 95% changed rapid insulin dose based on glucose levels and 18% considered carbohydrates in their rapid insulin dosing. Mean glycosilated hemoglobin was 8.18±0.23% without differences by sex or pubertal status. Sex, pubertal stage and the number of insulin doses did not contribute to glycosilated hemoglobin changes. There were no differences in weight or BMI, but there was a decrease in height Z score from the admission to the program until the last control (0.1±0.1 vs -0.3±0.1 DS; p

Scientific Electronic Library Online (Spanish)

23

Primigesta de edad avanzada

Obregón Yánez, Luisa E
2007-09-01

Resumen en español Objetivo: Comparar las primigestas de 35 años y más, atendidas en dos lapsos con 10 años de diferencia, en el control prenatal, evolución del trabajo de parto y parto, intervenciones, abortos así como las complicaciones materno fetales, entre sí y con las cifras totales de la maternidad. Métodos: Estudio descriptivo, retrospectivo y comparativo de las historias médicas de 98 y 89 primigestas de edad avanzada, localizadas mediante la revisión de los libros de admi (mas) siones desde 1º de enero al 31 de diciembre de 1993 y 2003. La inferencia estadística se realizó mediante la dócima de Chi cuadrado (X²) y de Z para la comparación de medias y porcentajes. Ambiente: Maternidad "Concepción Palacios", Caracas. Venezuela. Resultados: En los dos lapsos la incidencia fue de 0,38 % y 0,42 % , el promedio de edad 37,42 y 37,99 años, el 93,42 % y el 94,45 % refirieron haber realizado control prenatal la mayoría a nivel de hospitales privados, el número de consultas y de exámenes complementarios realizados aumentaron en el segundo lapso, las complicaciones del embarazo fueron numerosas predominando los trastornos hipertensivos del embarazo, en el 46 % y 52 % se realizó cesárea la mayoría de emergencia, las complicaciones intra y posparto y neonatal numerosas sin diferencias significativa. La mortalidad neonatal fue cuatro veces mayor que la de la Maternidad "Concepción Palacios" y hubo 2 muertes maternas en el segundo lapso. Conclusiones: Encontramos un aumento importante de la morbilidad materna predominando los trastornos hipertensivos del embarazo, del ingreso de pacientes multirreferidas, de la incidencia de cesáreas, de la morbimortalidad perinatal y de la mortalidad materna por ello se debe considerar a la primigesta de edad avanzada como un embarazo de muy alto riesgo en nuestra institución Resumen en inglés Objective: To compare primigravida's women aged 35 or over, attended in two different periods with ten years between them, regarding to prenatal control, labor and childbirth, interventions, abortions as well as mother and child complications. These periods will be compared between them and with the medical center data. Methods: Descriptive and retrospective analysis of medical records of 98 and 89 advanced maternal age women, which were found in the admission books from (mas) january 1st to december 31st of 1993 and 2003. Statistics were evaluated trough X² and Z for media and percentages comparison. Setting: Maternidad "Concepcion Palacios", Caracas Venezuela. Results: The incidence of delayed maternity in 1993 and 2003 was 0.38 % and 0.42 % respectively. The average age was 37.42 and 37.99 years old; 93.42 and 94.45 % of patients referred to have prenatal control, the most in private medical centers. The number of consults and complementary tests increased in second period. Pregnancy complications were numerous, being pregnancy-induced hypertension the most common. Cesarean was performed in 46 and 52 %, the most of them in emergency. Complications during and post labor as well as neonatal were numerous but none of them showed a significant difference. Neonatal mortality was four times higher than reported for Maternidad "Concepcion Palacios" and two mother deceased occurred during second period. Conclusions: We found an important increase of mother morbidity, with predominance of hypertension. It was also noticed a raise of entries of multi referred patients, cesarean incidence, perinatal morbimortality and mother mortality. Due to these facts is necessary to consider the primiparous women aged 35 or over as a high risk pregnancy in our institution

Scientific Electronic Library Online (Spanish)

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Portadores Orofaríngeos de Haemophilus Influenzae en Niños Venezolanos Cuidados en Guardería o en el Hogar Vacunados o no con Vacuna Poliribofosfato Capsular de Hib Conjugada alToxoide Tetánico (PRP-T)/ Oropharyngeal Carriers in Venezuelan Children in two Child care Settings, Vaccinated or not with Haemophilus Influenzae type b Tetanus Toxoid Conjugate Vaccine (PRP-T)

Castillo-Febres, Olga; López, Giomaris; Ortega, Federico; Estopiñan, Milagros; Casanova-Escalona, Laddy; Sánchez-Naveda, Miriam; Decker, Michael; Edwards, Kathryn M
2005-03-01

Resumen en español El objetivo del estudio fue determinar el porcentaje de colonización orofaríngea de Haemophilus influenzae tipo b (Hib) y no tipificable (HiNT) en niños, cuidados en guardería y en hogar vacunados o no con PRP/T. Se incluyeron niños sanos, menores de 7 años, excluyendo aquellos con antibióticoterapia el mes previo a la inclusión, divididos en: Grupo I vacunados y Grupo II no vacunados, subdivididos según cuidados en hogar o guardería. Se obtuvieron hisopados oro (mas) faríngeos para cultivo, identificación y serotipificación de Hi (Phadebact Test); como medidas estadísticas se utilizaron Chi cuadrado, test de Fisher’s y Z y el "odds ratio". Se incluyeron 320 niños, 99 del Grupo I (49 en hogar y 50 en guarderías) y 221 en Grupo II (94 y 127, respectivamente). El porcentaje de portadores fue 22,8 (17,8% HiNT y 5% Hib). En el grupo I sólo se identificó HiNT y en el grupo II, de 56 cepas, 16 fueron Hib (p = 0,016). Predominó el Hib en guarderias (odds ratio = 13,5). La colonización por HiNT fue similar en ambos grupos, cuidados en el hogar (18 vs 19%) y en guarderías (16 vs 17%). En el grupo II la colonización por Hib fue mayor en guarderías (12%) que en el hogar (1%) (p = 0,002). En conclusión, el porcentaje de colonización por Hib en la muestra total y en no vacunados del hogar fue semejante a países desarrollados en la era prevacuna. La ausencia de la vacuna PRP-T y la asistencia a guarderías son factores de riesgo para colonización por Hib. Resumen en inglés The objective was to estimate the oropharyngeal carrier rate of Haemophilus influenzae type b (Hib) and non typeable (NTHi) in unvaccinated and vaccinated children, with PRP/T vaccine, both cared at home and attending day care centers. Healthy children of either sex, younger of 7 years, excluding those that received antibiotics one month prior to the inclusion, were recruited from control clinics for healthy babies, and assigned to Group I fully immunized and Group II uni (mas) mmunized. Both, children cared at home and attending day care centers were included. Parents provided an informed consent. Specimens were obtained from the oropharynx for culture, identification and serotyped by slide agglutination (Phadebact Haemophilus test). P values were obtained with Chi-square, Fisher’s and Z test. Odds ratio was obtained when appropriated. Results were as following: a total of 320 children were enrolled, 99 in group I (49 cared at home, 50 attending day care) and 221 in group II (94 cared at home, 127 attending day care) the percentage of carriers was 22.8% (17.8% NTHi and 5% Hib). The carriage rate of NTHi was similar in groups I and II cared at home (18%vs 19%), and for those attending day care were 16% vs 17%. Carriage rate of Hib in children attending day care of group II was 12% vs 1% of those cared at home (p=0.002). None of the children in group I was colonized by Hib. The Hib carrier rate was more similar to that of industrialized countries in the pre vaccine era in children cared at home, however, attendance to a day care center significantly increases its risk. The PRP/T vaccine appears to prevent the carrier state in both care settings.

Scientific Electronic Library Online (Spanish)

26

PHF6 mutations in T-cell acute lymphoblastic leukemia

Van Vlierberghe, Pieter; Palomero, Teresa; Khiabanian, Hossein; Joni Van der Meulen; Castillo, Mireia; Van Roy, Nadine; Moerloose, Barbara de; Philippé, Jan; González-García, Sara; Toribio, María Luisa; Taghon, Tom; Zuurbier, Linda; Cauwelier, Barbara; Harrison, Christine J.; Schwab, Claire; Pisecker, Markus; Strehl, Sabine; Langerak, Anton W.; Gecz, Jozef; Sonneveld, Edwin; Pieters, Rob; Paietta, Elisabeth; Rowe, Jacob M.; Wiernik, Peter H.; Benoit, Yves; Soulier, Jean; Poppe, Bruce; Yao, Xiaopan; Cordon-Cardo, Carlos; Meijerink, Jules; Rabadan, Raul; Speleman, Frank; Ferrando, Adolfo
2010-03-14

Digital.CSIC (Spain)

27

Obesidad en preescolares de la Región Metropolitana de Chile/ Obesity among preschool children of Santiago, Chile

Kain B, Juliana; Lera M, Lydia; Rojas P, Juanita; Uauy D, Ricardo
2007-01-01

Resumen en inglés Background: In Chile, obesity is currently the main nutritional problem. Since prevention should start early in life, it is important to determine the prevalence of obesity during childhood according to age category. Aim: To determine and compare the evolution of the obesity prevalence and other anthropometric indicators in preschool children between 2002 and 2004. Material and methods: Twice a year, we analyzed the data of children aged 2 to 4 yrs, from day care centers (mas) belonging to the National Association of Day Care Centers located in Greater Santiago, from 2002 till 2004 (the number of children included on each point in time fluctuated between 3,500 and 10,000). Cross-sectional and longitudinal analyses were carried out to determine the evolution of obesity prevalence, weight for age (WA) and body mass index (BMI) Z scores (according to the Centers for Disease Control 2000 reference) on preschoolers who were 2 years old in March 2002 and that were followed 3 years, until November 2004. These parameters were compared by age and gender over time. Results: The prevalence of obesity varied between 11 and 13.6% in two-year old children and between 17% and 20% in three and four year olds. The cross-sectional analysis showed that WA and BMI Z scores were significantly lower at 2 years of age, while the longitudinal analysis clearly demonstrated that there was a sharp rise in obesity between 2 and 3 years of age. Conclusions: The prevalence of obesity is high in preschool children, especially among the 3 and 4 year-olds with a significant rise from 2 to 3 years of age

Scientific Electronic Library Online (Spanish)

28

Nucleoporins Prevent DNA Damage Accumulation by Modulating Ulp1-dependent Sumoylation Processes

Palancade, Benoit; Xianpeng, Liu; García-Rubio, María L.; Aguilera, Andrés; Xiaolan, Zhao; Doye, Valérie
2007-08-01

Digital.CSIC (Spain)

29

N-methyl-D-aspartate activates different channels than do kainate and quisqualate

Lerma Gómez, Juan; Kushner, Leslie; Zukin, R. Suzanne; Bennet, Michael V.
1989-03-01

Digital.CSIC (Spain)

30

Molecular Cloning, Functional Characterization, and Subcellular Localization of Soybean Nodule Dihydrolipoamide Reductase

Morán, José F.; Sun, Z. H.; Sarath, G.; Arredondo-Peter, R.; James, E. K.; Becana Ausejo, Manuel; Klucas, R. V.
2002-01-01

Digital.CSIC (Spain)

31

Microscopic structure and dynamics of molten Se50Te50 alloys

Katcho, N. A.; Zetterström, P.; Lomba, Enrique; Otero Díaz, L. C.
2007-10-10

Digital.CSIC (Spain)

32

Metodología clásica y molecular en la identificación de especies de Enterococcus spp/ Classic and molecular methodologies for the identification of Enterococcus species

Sepúlveda A, Marcela; Bello T, Helia; Ruiz C, Mery; Hormazábal F, José; Domínguez Y, Mariana; González R, Gerardo; Mella M, Sergio; Zemelman Z, Raúl
2002-01-01

Resumen en inglés Background: Enterococcus is a bacterial genus with low virulence. However, in the last years, the importance of some enterococcus species as nosocomial pathogens has increased, specially due to their resistance to some antimicrobial. Aim: To identify enterococcus strains using classical biochemical techniques and genomic amplification with Polymerase Chain Reaction (PCR). Material and methods: Three hundred and five enterococcus strains, isolated between 1996 and 1999, fr (mas) om different clinical specimens in hospitals and other centers of the VIIIth Region of Chile, were studied. The isolates were identified, to the species level, according to the scheme proposed by Carvalho et al. Identification of some strains was confirmed by PCR. Results: Eighty nine percent of isolates were identified as E fæcalis, 10.2% as E fæcium and 3.3% as other species. Conclusions: PCR is a fast and promising technique, useful in the identification of Enterococcus species (Rev Méd Chile 2002; 130: 45-49)

Scientific Electronic Library Online (Spanish)

33

Measuring Baryon Acoustic Oscillations along the line of sight with photometric redshifts: the PAU survey

Benítez, Narciso; Gaztañaga, Enrique; Miquel, R.; Castander, Francisco J.; Molés, Mariano; Crocce, Martín; Fernández-Soto, Alberto; Fosalba, Pablo; Ballesteros, F.; Campa, J.; Cardiel-Sas, L.; Castilla, J.; Cristóbal-Hornillos, David; Delfino, M.; Fernández, E.; Fernández-Sopuerta, Carlos; García-Bellido, Juan; Lobo, J. Alberto; Martínez, Vicente J.; Ortiz, A.; Pacheco, A.; Paredes, S.; Pons-Bordería, M. J.; Sánchez, E.; Sánchez, Sebastián F.; Varela, Jesús; Vicente, J. F. de
2009-01-09

Digital.CSIC (Spain)

34

Measurement of σ(p[overline](p) -> Z) · B(Z -> ττ) in p[overline](p) collisions at sqrt(s)=1.96 TeV

Abulencia, A.; Adelman, J.; Affolder, T.; Akimoto, T.; Albrow, M. G.; Ambrose, D.; Amerio, S.; Amidei, D.; Anastassov, A.; Anikeev, K.; Annovi, A.; Bolla, G.; Deninno, M.; Sfyrla, A.; Shapiro, M. D.; Shears, T.; Lungu, G.; Shepard, P. F.; Sherman, D.; Haber, C.; Berry, T.; Pursley, J.; Cortiana, G.; Shimojima, M.; Shochet, M.; Shon, Y.; Shreyber, I.; Sidoti, A.; De Pedis, D.; Lyons, L.; Bolshov, A.; Sinervo, P.; Blocker, C.; Kephart, R.; Sisakyan, A.; Sjolin, J.; Kim, Y. K.; Hahn, K.; Slaughter, A. J.; Slaunwhite, J.; Sliwa, K.; Smith, J. R.; Lys, J.; Rademacker, J.; Snider, F. D.; Lister, A.; Snihur, R.; Derwent, P. F.; Soderberg, M.; Bortoletto, D.; Kimura, N.; Soha, A.; Hahn, S. R.; Somalwar, S.; Rahaman, A.; Sorin, V.; Cyr, D.; D'Onofrio, M.; Spalding, J.; Spinella, F.; Spreitzer, T.; Squillacioti, P.; Stanitzki, M.; Di Giovanni, G. P.; Kirsch, L.; Ranjan, N.; Staveris-Polykalas, A.; Denis, R. S.; Halkiadakis, E.; Mumford, R.; Lysak, R.; Boudreau, J.; Stelzer, B.; Stelzer-Chilton, O.; Stentz, D.; Strologas, J.; Kim, H. S.; Stuart, D.; Suh, J. S.; Klimenko, S.; Sukhanov, A.; Murat, P.; Dionisi, C.; Lytken, E.; Sun, H.; Coca, M.; Suzuki, T.; Rappoccio, S.; Taffard, A.; Boveia, A.; Takashima, R.; Takeuchi, Y.; Takikawa, K.; Nachtman, J.; Klute, M.; Tanaka, M.; Jung, J. E.; Tanaka, R.; Reisert, B.; Tecchio, M.; Di Ruzza, B.; Hamilton, A.; Teng, P. K.; Terashi, K.; Thom, J.; Nagano, A.; Thompson, A. S.; Brau, B.; Knuteson, B.; Dell'Orso, M.; Azfar, F.; Thomson, E.; Tipton, P.; Tiwari, V.; Tkaczyk, S.; Toback, D.; Azzurri, P.; Naganoma, J.; Dittmann, J. R.; Tokar, S.; Lu, R. S.; Tollefson, K.; Tomura, T.; Mack, P.; Ko, B. R.; Tonelli, D.; Torre, S.; Brigliadori, L.; Torretta, D.; Nakano, I.; Tourneur, S.; Mohr, B.; Trischuk, W.; Han, B. Y.; Tsuchiya, R.; DiTuro, P.; MacQueen, D.; Tsuno, S.; Kondo, K.; Turini, N.; Ukegawa, F.; Goshaw, A. T.; Azzi-Bacchetta, P.; Unverhau, T.; Uozumi, S.; Usynin, D.; Bromberg, C.; Vallecorsa, S.; Han, J. Y.; Bellinger, J.; Van Remortel, N.; Varganov, A.; Bartsch, V.; Rekovic, V.; Napier, A.; Dorr, C.; Vataga, E.; Vázquez, F.; Velev, G.; Veramendi, G.; Veszpremi, V.; Vidal, R.; Madrak, R.; Vila, Iván; Renton, P.; Handler, R.; Necula, V.; Brubaker, E.; Giurgiu, G.; Vilar, Rocío; Vine, T.; Donati, S.; Vollrath, I.; Volobouev, I.; Volpi, G.; Rescigno, M.; Maeshima, K.; Wurthwein, F.; Litvintsev, D. O.; Wagner, P.; Wagner, R. G.; Happacher, F.; Kong, D. J.; Wagner, R. L.; Wagner, J.; Budagov, J.; Richter, S.; Wagner, W.; Arguin, J. F.; Makhoul, K.; Cordelli, M.; Wallny, R.; Wang, S. M.; Warburton, A.; Waschke, S.; Waters, D.; Antos, J.; Rimondi, F.; Hara, K.; Weinberger, M.; Wester, W. C.; Whitehouse, B.; Neu, C.; Maki, T.; Whiteson, D.; Budd, H. S.; Donega, M.; Wicklund, A. B.; Blumenfeld, B.; Wicklund, E.; Williams, G.; Konigsberg, J.; Williams, H. H.; Hare, M.; Neubauer, M. S.; Wilson, P.; Maksimovic, P.; Winer, B. L.; Wittich, P.; Kim, J. E.; Wolbers, S.; Wolfe, C.; Wright, T.; Dong, P.; Budd, S.; Korytov, A.; Dagenhart, D.; Wu, X.; Wynne, S. M.; DaRonco, S.; Ristori, L.; Harper, S.; Yagil, A.; Yamamoto, K.; Yamaoka, J.; Yamashita, T.; Yang, C.; Yang, U. K.; Bhatti, A.; Yang, Y. C.; Kotwal, A. V.; Robson, A.; Donini, J.; Junk, T. R.; Yao, W. M.; Budroni, S.; Harr, R. F.; Yeh, G. P.; Yoh, J.; Yorita, K.; Nielsen, J.; Yoshida, T.; Moore, R.; Yu, G. B.; Yu, I.; Kovalev, A.; Malde, S.; Yu, S. S.; Yun, J. C.; Dorigo, T.; Zanello, L.; Compostella, G.; Nigmanov, T.; Golossanov, A.; Zanetti, A.; Burkett, K.; Zaw, I.; Zhang, X.; Zhou, J.; Clark, A.; Kraan, A. C.; Zucchelli, S.; Busetto, G.; Bussey, P.; Rodrigo, Teresa; Nodulman, L.; Byrum, K. L.; Dube, S.; Harris, R. M.; Cabrera, Susana; Campanelli, M.; Campbell, M.; Manca, G.; Canelli, F.; Kraus, J.; Rogers, E.; Canepa, A.; Norniella, O.; Carillo, S.; Carlsmith, D.; Carosi, R.; Carron, S.; Casarsa, M.; Hartz, M.; Efron, J.; Margaroli, F.; Grosso-Pilcher, C.; Castro, A.; Catastini, P.; Goulianos, K.; Kravchenko, I.; Cauz, D.; Cavalli-Sforza, M.; Cerri, A.; Cerrito, L.; Chang, S. H.; Chen, Y. C.; Paoli, F. D.; Chertok, M.; Marginean, R.; Bacchetta, N.; Liu, T.; Chiarelli, G.; Erbacher, R.; Kreps, M.; Chlachidze, G.; Chlebana, F.; Cho, I.; Rolli, S.; Cho, K.; Chokheli, D.; Chou, J. P.; Marino, C.; Nurse, E.; Choudalakis, G.; Chuang, S. H.; Hatakeyama, K.; Chung, K.; Glagolev, V.; Roser, R.; Chung, W. H.; Errede, D.; Chung, Y. S.; Ciljak, M.; Ciobanu, C. I.; Giromini, P.; Belloni, A.; Ciocci, M. A.; Errede, S.; Eusebi, R.; Rossi, M.; Arisawa, T.; Hauser, J.; Kroll, J.; Fang, H. C.; Farrington, S.; Fedorko, I.; Oh, S. H.; Fedorko, W. T.; Marino, C. P.; Feild, R. G.; Rossin, R.; Feindt, M.; Fernández, J. P.; Field, R.; Flanagan, G.; Foland, A.; Bauer, G.; Heijboer, A.; Oh, Y. D.; Artikov, A.; Forrester, S.; Kim, M. J.; Martin, A.; Foster, G. W.; Franklin, M.; Freeman, J. C.; Furic, I.; Gallinaro, M.; Galyardt, J.; García, J. E.; Oksuzian, I.; Crescioli, F.; Morello, M.; Garberson, F.; Heinemann, B.; Martin, M.; Garfinkel, A. F.; Ashmanskas, W.; Gay, C.; Gerberich, H.; Gerdes, D.; Giagu, S.; Okusawa, T.; Ruiz, Alberto; Giannetti, P.; Gibson, A.; Krumnack, N.; Gibson, K.; Kamon, T.; Gimmell, J. L.; Heinrich, J.; Ginsburg, C.; Giokaris, N.; Attal, A.; Jun, S. Y.; De Barbaro, P.; Giordani, M.; Henderson, C.; Herndon, M.; Convery, M. E.; Kruse, M.; Martin, V.; Heuser, J.; Hidas, D.; Hill, C. S.; Russ, J.; Badgett, W.; Oldeman, R.; Hirschbuehl, D.; Hocker, A.; Holloway, A.; Hou, S.; Houlden, M.; Hsu, S. C.; Datta, M.; Krutelyov, V.; Bocci, A.; Conway, J.; Huffman, B. T.; Binkley, M.; Hughes, R. E.; Husemann, U.; Huston, J.; Barbaro-Galtieri, A.; Incandela, J.; Introzzi, G.; Iori, M.; Rusu, V.; Gómez, G.; Ishizawa, Y.; Kubo, T.; Orava, R.; Ivanov, A.; Cooper, B.; Iyutin, B.; James, E.; Jang, D.; Jayatilaka, B.; Saarikko, H.; Jeans, D.; Barnes, V. E.; Martínez, M.; Jensen, H.; Lockyer, N. S.; Jeon, E. J.; Kuhlmann, S. E.; Jindariani, S.; Jones, M.; Copic, K.; Group, R. C.; Joo, K. K.; Kuhr, T.; Kusakabe, Y.; Glenzinski, D.; Maruyama, T.; Osterberg, K.; Kwang, S.; Laasanen, A. T.; Lai, S.; Cuenca Almenar, Cristóbal; Sabik, S.; Bedeschi, F.; Lami, S.; Lammel, S.; Lancaster, M.; Lander, R. L.; Lannon, K.; Gresele, A.; Mastrandrea, P.; Gold, M.; Lath, A.; Demortier, L.; Latino, G.; Lazzizzera, I.; LeCompte, T.; Cuevas, Javier; Lee, J.; Behari, S.; Lee, J.; Kerzel, U.; Lee, Y. J.; Masubuchi, T.; Safonov, A.; Lee, S. W.; Goldschmidt, N.; Lefevre, R.; Leonardo, N.; Leone, S.; Levy, S.; Lewis, J. D.; Culbertson, R.; Pagliarone, C.; Lin, C.; Fernández, P. M.; Lin, C. S.; Matsunaga, H.; Belforte, S.; Lindgren, M.; Goldstein, J.; Lipeles, E.; Mattson, ME.; Benjamin, D.; Karchin, P. E.; Palencia, Enrique; Sakumoto, W. K.; Mazini, R.; Mazzanti, P.; McFarland, KS.; Gómez-Ceballos, Guillelmo; D'Auria, S.; McIntyre, P.; McNulty, R.; Mehta, A.; Mehtala, P.; Menzemer, Stefanie; Baroiant, S.; Papadimitriou, V.; Barnett, B. A.; Menzione, A.; Merkel, P.; Beretvas, A.; Mesropian, C.; Goncharov, M.; Messina, A.; Davies, T.; Miao, T.; Bellettini, G.; Miladinovic, N.; Paramonov, A. A.; Miles, J.; Kato, Y.; Miller, R.; Mills, C.; Milnik, M.; Mitra, A.; Mitselmakher, G.; González, O.; Salamanna, G.; Beringer, J.; Miyamoto, A.; Parks, B.; Aoki, M.; Moed, S.; Kemp, Y.; Moggi, N.; Pashapour, S.; De Cecco, S.; Loginov, A.; Salto, O.; Patrick, J.; Pauletta, G.; Bisello, D.; Khotilovich, V.; Griffiths, M.; Paulini, M.; Paus, C.; Pellett, D. E.; Penzo, A.; Phillips, T. J.; Saltzberg, D.; Cully, J. C.; Piacentino, G.; Piedra, Jonatan; Deisher, A.; Pinera, L.; Kilminster, B.; Pitts, K.; Grinstein, S.; Plager, C.; Blair, R. E.; Sanchez, C.; Pondrom, L.; Loreti, M.; Portell, X.; Poukhov, O.; Pounder, N.; Prakoshyn, F.; Pronko, A.; Kim, D. H.; De Lentdecker, G.; Proudfoot, J.; Santi, L.; Clark, D.; Ptohos, F.; Loverre, P.; Punzi, G.; Bodek, A.; Grundler, U.; Mulmenstadt, J.; Sarkar, S.; Sartori, L.; Deng, J.; Lucchesi, D.; Kim, S. B.; Sato, K.; Savard, P.; Savoy-Navarro, A.; Scheidle, T.; Schlabach, P.; Gorelov, I.; Schmidt, E. E.; Schmidt, M. P.; Da Costa, J. G.; Schmitt, M.; Lujan, P.; Boisvert, V.; Kim, S. H.; Schwarz, T.; Apollinari, G.; Scodellaro, Luca; Mukherjee, A.; Scott, A. L.; Scribano, A.; Scuri, F.; Sedov, A.; Seidel, S.; Lukens, P.; Gunay-Unalan, Z.; Seiya, Y.; Giunta, M.; Semenov, A.; Muller, T.; Sexton-Kennedy, L.; [CDF Collaboration]
2007-05-18

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Increasing Omega-3 Desaturase Expression In Tomato Results In Altered Aroma Profile And Enhanced Resistance To Cold Stress

Domínguez, Teresa; Hernández, M. Luisa; Pennycooke, Joyce C.; Jiménez, Pedro; Martínez-Rivas, Jose Manuel; Sanz, Carlos; Stockinger, Eric J.; Sánchez Serrano, José J.; Sanmartín, Maite
2010-04-09

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Factores de riesgo asociados al estado nutricio en lactantes que son atendidos en guarderías/ Risk factors associated to the nutritional status of infants attending day care centers

Vásquez-Garibay, Edgar M; Ávila-Alonso, Eneida N; Contreras-Ramos, Tania; Cuellar-Espinosa, Luz A; Romero-Velarde, Enrique
2007-02-01

Resumen en español Introducción. Objetivo: identificar factores asociados al estado nutricio en lactantes de 3 a 12 meses de edad que acuden a guarderías en Guadalajara. Material y métodos. En un estudio transversal, se incluyeron 123 lactantes de 3 a 12 meses de edad de cinco guarderías del Instituto Mexicano del Seguro Social de Guadalajara. Se consideró déficit en índices de longitud/edad, peso/edad y peso/longitud con puntuación Z (mas) ariables sociodemográficas, económicas, dietéticas, patológicas y de dinámica familiar. Con razón de momios (RM) y un modelo de regresión logística se identificaron variables con factores de riesgo de desnutrición. Resultados. El ingreso de la madre, inferior a 3 salarios mínimos [RM 3.95 (1.38-11.4), P =0.003], fin del destete tardío [RM 6.71 (1.92-24-4), P 8 horas en guarderías (P Resumen en inglés Introduction. Objective: To identify risk factors associated to the nutritional status of infants 3 to 12 months of age attending to day care centers in Guadalajara, Mexico. Material and methods. In a cross sectional study 123 infants 3 to 12 months from 5 day care centers of Guadalajara were included. It was considered deficit of indices length/age, weight/age and weight/length with Z score (mas) ariables were explored. With odds ratio and logistic regression, model variables with malnutrition risk factors were identified. Results. The mother's income lower than 3 minimum wage [OR 3.95 (1.38-11.4), P =0.003]; delayed weaning [RM 6.71 (1.92-24-4), P

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Evaluación de los criterios de Nugent y Amsel para el diagnóstico de vaginosis bacteriana/ Evaluation of Nugent and Amsel criteria for the diagnosis of bacterial vaginosis

Navarrete W, Paola; Domínguez Y, Mariana; Castro I, Erica; Zemelman Z, Raúl
2000-07-01

Resumen en inglés Background: Bacterial vaginosis (BV) is a common disease in reproductive-age women and is associated to important gynecologic and obstetric complications. Aim: To study the occurrence of BV in apparently healthy women attending family planning clinics, using Amsel and Nugent diagnostic criteria. Material and methods: Two hundred thirty nine women consulting for symptoms associated to cervicovaginitis, were studied. A sample from the lateral walls of the vagina was obtaine (mas) d with a sterile swab for microscopic analysis, Gram stain and amine test. Results: According to Amsel and Nugent criteria a 31.1% and 31.8% BV prevalence was observed. The sensitivity and specificity of Nugent criteria, compared with Amsel criteria were 83.3% and 92.1%, respectively. Conclusions: The high prevalence of BV found in this study suggests that this vaginal infection should be diagnosed with standardized methods. Nugent criteria are economic easy to perform and sensitive and we propose that they should be used in local health centers. (Rev Méd Chile 2000; 128: 767-71)

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Efecto del consumo de un complemento alimentario en la concentración plasmática de cinc en adultos mayores residentes en Santiago de Chile/ Effect of the consumption of a food supplement on plasma zinc concentrations of free-living Chilean elderly adults

Ramos H, Rosa Isela; Atalah S, Eduardo; Urteaga R, Carmen; Castañeda L, Rutila; Orozco L, Maribel; Avila, Laura; Martínez, Homero
2007-08-01

Resumen en inglés Background: Zinc intake is well below recommendation among Chilean free living elderly adults of low socioeconomic level Aim: To assess the effect of the consumption of a food supplement on plasma zinc concentrations in elderly adults (EA). Material and Methods: Ambulatory EA (z70) with controlled type 2 diabetes mellitus or high blood pressure, ascribed to public family health centers were studied. They were separated in a control and intervention group, without blinding (mas) techniques. The intervention group consumed daily 50 g of a special nutritional supplement prepared as a soup or porridge, provided by the Government, for 3 months. The control group did not receive the supplement. A good compliance with the supplement was defined as a consumption of 7 portions per week. A fasting venous blood sample was obtained to determine plasma zinc at the beginning and end of the study. Results: Forty three supplemented EA aged 76±5 years (21 women) and 31 non supplemented EA aged 78±5 years (20 women), completed 3 months of follow up. Mean compliance with the supplement was 40.5% (95% confidence intervals (CI) 40.3-40.6%). General characteristics of the study subjects upon recruitment were similar, except for the literacy that was higher in the intervention group. We fitted a multiple linear regression model which explained 39% of the variance, where the consumption of the nutritional supplement increased the concentration ofplasmatic zinc by 4.14 fig/dL (95% CI 0.25-8.02) (p

Scientific Electronic Library Online (Spanish)

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Combinatorial Number Theory and Additive Group Theory

Geroldinger, Alfred; Ruzsa, Imre Z.; Cilleruelo, Javier; Serra, Oriol
2009-01-01

Digital.CSIC (Spain)

41

Coexpression of N-methyl-D-aspartate and phencyclidine receptors in Xenopus oocytes injected with rat brain mRNA

Kushner, Leslie; Lerma Gómez, Juan; Zukin, R. Suzanne; Bennet, Michael V.
1988-05-01

Digital.CSIC (Spain)

42

Backbone conformational preferences and pseudorotational ring puckering of 1-aminocyclopentane-1-carboxylic acid

Alemán, Carlos; Zanuy, David; Casanovas, Jordi; Cativiela, Carlos; Nussinov, Ruth
2006-09-23

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Alteraciones de la conducta alimentaria en lactantes chilenos, de acuerdo a estrato socioeconómico/ Eating behavior disorders in Chilean infants, according to socioeconomic level

Sánchez, Susana; Castillo D, Carlos
2008-12-01

Resumen en español Las alteraciones de la conducta alimentaria son frecuentes en niños; pero se conocen poco sus características en niños/as Latinoamericanos y sus diferencias por estrato socioeconómico (ESE). El objetivo fue caracterizar las alteraciones de la conducta alimentaria (ACA) en lactantes chilenos según ESE bajo (ESEB) o medio alto (ESEMA). Se estudiaron prospectivamente 67 niños/as(as) (4-24 m) de Santiago, Chile; el grupo estudio (GE) lo constituyeron 34 niños/as(as) co (mas) nsultando por signos de ACA, de los cuales 18 fueron de ESEB y 16 de ESEMA; el grupo control (GC) se constituyó por 33 niños/as(as) sin ACA, pareados por edad, sexo y ESE con el GE, (15 niños/as de ESEB y 18 de ESEMA). Se aplicó una encuesta semiestructurada a la madre o cuidador. Como resultados, el GE tuvo menor puntaje z peso/edad (z P/E) en ambos ESE (GE: -0,9 ± 1,0; GC: +0,5 ± 0,9; p=0,0001); en el ESEB fue menor la talla/edad (z T/E) del GE (GE -1,0 ± 1,0 vs GC -0,3 ± 0,8; p=0,01) y el peso de nacimiento (PN) (GE= 3,1 ± 0,5 kg; GC=3,6 ± 0,4 kg; p=0,001). En el ESEMA, en el GE hubo más niños/as con lactancia materna exclusiva (LME) 4m y las madres trabajaban más horas diarias que en el GC (7,6 ± 4,1 vs 5,4 ± 1,8 h/día; p=0,007). Como conclusiones: los lactantes con alteraciones de la conducta alimentaria tuvieron menor z P/E y z P/T (independiente del estrato socioeconómico). En el estrato socioeconómico bajo ellos presentaron menor peso de nacimiento y menor puntaje z T/E que los controles. En los estratos socioeconómicos medio-altos fueron más los niños/as con alteraciones de la conducta alimentaria que presentaban lactancia materna abreviada y sus madres trabajaban más horas fuera del hogar, que los controles. Resumen en inglés The eating behavior disorders in infants (EDI) are frequently diagnosed in children; however, information about their characteristics or differences by socioeconomic level (SL) in Chile and Latin America, are missing. The objective was to characterize the urban Chilean infants with EDI, according to socioeconomic level. Sixty seven children were studied (4-24 months of age). The study group (SG) was constituted by 34 children attending clinics because of EDI: 18 belonged (mas) to low SL (LSL) and 16 to middle or high income groups (MHSL). Thirty three without EDI served as controls (CG), and were paired by age, gender and SL with SG (15 of them belonged to LSL and 18 to MHSL). A semi structured survey was applied to parents or caretakers. Children from LSL were studied at Primary Health Care Centers and those from MHSL at private clinics. The results showed: the mean weight/age z-score (W/A) was lower in the SG especially in LSL (SG: -0.9 ± 1.0; CG: 0.5 ± 0.9; p=0.0001), the height/age z-score (z H/A) in SG was: -1.0 ± 1.0 and in CG was: -0.3 ± 0.8; p=0.01) and the birth weight was SG=3.1± 0.5 kg; CG=3.6 ± 0.4 kg; (p=0,001), were lower only for the SG of LSL. In the MHSL, exclusive breast feeding ≤ 4m was more frequent in the SG than the CG and the mothers worked more hours daily outside of their homes (7,6 ± 4,1 vs 5,4 ± 1,8 h/d; p=0,007). As conclusions, the Chilean infants with eating behavior disorders had lower z W/A and lower z W/L than those with no EDI, independent of socioeconomic level. The infants of LSL with EDI also had lower z H/A and also lower birth weight than controls. In the medium-high socioeconomic level, those with eating disorders presented shorter breast feeding (≤ 4m) and their mothers worked more hours daily outside of their homes, than those without eating disorders.

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Accesibilidad geográfica para detección temprana de enfermedades crónico-degenerativas/ Estimation of a geographic accessibility index of different health centers in México

Garza-Elizondo, María Eugenia; Salinas-Martínez, Ana María; Núñez-Rocha, Georgina Mayela; Villarreal Ríos, Enrique; Vásquez-Treviño, María Guadalupe; Vásquez-Salazar, María Guadalupe
2008-12-01

Resumen en inglés Background: The accessibility to health centers is a limitation to the use of preventive and curative health centers. Aim: To assess geographic accessibility using a parameter that integrates information about the use ofpreventive services and travelling time froin home to the health center. Material and methods: We analyzed target geographical áreas of10 community centers located at the Northeast of México. A survey was conducted to collect information about the utiliz (mas) ation of preventive services for detection of diabetes and hypertension within last year and in women, detection of cervical and breast cáncer. The time required to travel between the health center and the farthest location point at every neighborhood of each geographic área, using public or private transportation, was calculated. Health service use and transportation time were condensed in a single parameter, called geographic accessibility index. Data was normalized using z scores. Resulte: Three geographical areas denominated 7, 8 and 10 had the lowest detection rates of chronic diseases, with valúes rangingfrom 45% to 48%. By car, área number 3 had the longest travelling time, corresponding to 14 minutes. The longest travelling times by public transportation were detected in áreas 1 and 3, corresponding to 27 and 29 minutes, respectively The geographic accessibility index showed that the least favorable z scores travelling by car corresponded to areas 6 and 10 and, when travelling on public transportation, to áreas 8 and 10. Conclusions: The geographic accessibility index identified areas that required improvements in accessibility

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A Draft Sequence of the Neandertal Genome.

Green, Richard E.; Krause, Johannes; Briggs, Adrian W.; Maricic, Tomislav; Stenzel, Udo; Kircher, Martin; Patterson, Nick; Li, Heng; Zhai, Weiwei; Hsi-Yang Fritz, Markus; F. Hansen, Nancy; Durand, Eric Y.; Malaspinas, Anna-Sapfo; Jensen, Jeffrey D.; Marqués-Bonet, Tomàs; Alkan, Can; Prüfer, Kay; Meyer, Matthias; Burbano, Hernán A.; Good, Jeffrey M.; Schultz, Rigo; Aximu-Petri, Ayinuer; Butthof, Anne; Höber, Barbara; Höffner, Barbara; Siegemund, Madlen; Weihmann, Antje; Nusbaum, Chad; Lander, Eric S.; Russ, Carsten; Novod, Nathaniel; Affourtit, Jason; Egholm, Michael; Verna, Christine; Rudan, Pavao; Brajković, Dejana; Kućan, Zeljko; Gusić, Ivan; Doronichev, Vladimir B.; Golovanova, Liubov V.; Lalueza-Fox, Carles; Rasilla, Marco de la; Fortea, Javier; Rosas, Antonio; Schmitz, Ralf; Johnson, Philip L. F.; Eichler, Evan E.; Falush, Daniel; Birney, Ewan; Mullikin, James C.; Slatkin, Montgomery; Nielsen, Rasmus; Kelso, Janet; Lachmann, Michael; Reich, David; Pääbo, Svante
2010-05-07

Digital.CSIC (Spain)