Sample records for TIMOCITOS (thymocytes)
from WorldWideScience.org

Sample records 1 - 15 shown.



3

Plasmacytoid dendritic cells resident in human thymus drive natural Treg cell development

Martín-Gayo, Enrique; Sierra-Filardi, Elena; Corbí, Ángel; María Luisa, Toribio
2010-03-31

Digital.CSIC (Spain)

5

Linomide prevents the lethal effect of anti-fas antibody and reduces fas-mediated ceramide production in mouse hepatocytes

Redondo, Clara; Flores, Ignacio; González, Ana; Nagata, Shigekazu; Carrera, Ana C.; Mérida, Isabel; Martínez-Alonso, Carlos

DRIVER (Spanish)

6

Linomide prevents the lethal effect of anti-fas antibody and reduces fas-mediated ceramide production in mouse hepatocytes

Redondo, Clara; Flores, Ignacio; González García, Ana; Nagata, Shigekazu; Carrera, Ana C.; Mérida, Isabel; Martínez-Alonso, Carlos
1996-09-01

Digital.CSIC (Spain)

7

Involvement of the interleukin 2 pathway in the rearrangement and expression of both [alfa/beta] and [gamma/delta] T cell receptor genes in human T cell precursors

Toribio, María Luisa; Hera, Antonio de la; Borst, Jannie; Borst, Jannie; Marcos, Miguel A. R.; Márquez, Carlos; Alonso, José M.; Bárcena, Alicia; Martínez-Alonso, Carlos
1988-12-01

Digital.CSIC (Spain)

8

IL-2 protects against anti-CD3-induced cell death in human medullary thymocytes

Nieto, M. Ángela; González, A.; López-Rivas, Abelardo; Díaz-Espada, F.; Gambón, F.
1990-09-01

Digital.CSIC (Spain)

9

IL-2 protects T cell hybrids from the cytolytic effect of glucocorticoids. Synergistic effect of IL-2 and dexamethasone in the induction of high-affinity IL-2 receptors

Fernández-Ruiz, E.; Rebollo, A.; Nieto, M. Ángela; Sanz, E.; Somoza, C.; Ramírez, F.; López-Rivas, Abelardo; Silva González, Augusto
1989-01-01

Digital.CSIC (Spain)

10

EFECTOS DE LA DESNUTRICIÓN PROTEICA Y DE SU RECUPERACIÓN NUTRICIONAL EN EL TIMO DE RATA/ EFFECTS OF PROTEIN MALNUTRITION AND ITS NUTRITIONAL RECOVERY IN RATS´ THYMUS

Feliu, María S.; Slobodianik, Nora H.
2002-08-01

Resumen en español El objetivo de este trabajo fue estudiar el contenido de DNA y la actividad de Adenosina Deaminasa (ADA), Purina Nucleósido Fosforilasa(PNP) y 5’ Nucleotidasa (5´NT) -enzimas relacionadas con el desarrollo y funcionamiento de los linfocitos T- en el timo de ratas con desnutrición proteica leve, moderada y severa al destete y la posterior recuperación nutricional. El estrés nutricional causado por la administración desde el destete de dietas carentes de proteínas p (mas) rovocó una disminución del peso del timo, del contenido de DNA y un aumento en la actividad de ADA y PNP sin modificar la actividad de 5’NT. Este aumento de actividad podría explicarse como un mecanismo para evitar la formación de productos potencialmente tóxicos para los linfocitos T. La administración de la dieta de recuperación fue capaz de revertir los efectos provocados por la desnutrición proteica al destete; no se observaron diferencias significativas en los parámetros estudiados, entre el grupo realimentado y su control bien nutrido de igual edad. Estos hallazgos avalan la hipótesis relacionada con el equilibrio de nutrientes en la dieta y la evolución del desarrollo celular tímico Resumen en inglés The thymus is severely affected by nutritional disorders. The activity of Adenosine deaminase (ADA), purine nucleoside phosphorylase (PNP) and 5’nucleotidase (5’NT) might affect T cell development. We study the effect of feeding growing rats with a protein-free diet and the posterior effect of a complete diet in the recovery of the thymus.. Changes in thymus weight, DNA content and the activity of ADA, PNP and 5’NT were determined in thymocytes’ suspensions. The resul (mas) ts indicate that the nutritional stress provoked by the administration of a protein-free diet from weaning onwards, affects the development of thymus expressed as loss of weight and DNA content, with an concomitant increase in the activity of ADA and PNP without 5’NT changes. The increase would be an alternative mechanism to avoid the accumulation of high levels of deoxynucleotides, which would be toxic for T lymphocytes. The recovery diet was capable to reverse the effects provoked by the administration of experimental diets. This work reinforces our hypothesis related to diet as an important modifying factor that affects T lymphocyte development

Scientific Electronic Library Online (Spanish)

11

CSL–MAML-dependent Notch1 signaling controls T lineage–specific IL-7R gene expression in early human thymopoiesis and leukemia

González-García, Sara; García-Peydró, Marina; Martín-Gayo, Enrique; Ballestar, Esteban; Esteller, Manel; Bornstein, Rafael; de la Pompa, Jose L.; Ferrando, Adolfo; Toribio, María Luisa
2009-04-01

Digital.CSIC (Spain)

12

Apoptosis in human thymocytes after treatment with glucocorticoids

Nieto, M. Ángela; González, A.; Gambón, F.; Díaz-Espada, F.; López-Rivas, Abelardo
1992-05-01

Digital.CSIC (Spain)

13

A role for stroma-derived annexin A1 as mediator in the control of genetic susceptibility to T-cell lymphoblastic malignancies through prostaglandin E2 secretion

Santos, Javier; González-Sánchez, Laura; Matabuena-deYzaguirre, María; Villa-Morales, María; Cozar, Patricia; López-Nieva, Pilar; Fernández-Navarro, Pablo; Díaz-Muñoz, Manuel D.; Guenet, Jean-Louis; Montagutelli, Xavier; Fernández-Piqueras, José
2009-03-15

Digital.CSIC (Spain)

14

A conformational change senses the strength of T cell receptor–ligand interaction during thymic selection

Risueño, Ruth M.; van Santen, Hisse M.; Alarcón, Balbino

T cell antigen receptor (TCR) triggering determines the fate of immature thymocytes. The affinity of the TCR for its endogenous peptide/MHC ligands serves as a signal for positive or negative selection through mechanisms that are still little understood. We have used a conformation-specific antibody...

DRIVER (Spanish)