Sample records for DESTRUCCION DE LAS CELULAS (cell killing)
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2

TRYPANOSOMA HUMBOLDTI EN SCHROEDERICHTHYS CHILENSIS (CHONDRICHTHYES, ELASMOBRANCHII, SCYLIORHINIDAE) COMO INDICADOR NO DESTRUCTIVO DE CONTAMINACION/ TRYPANOSOMA HUMBOLDTI IN SCHROEDERICHTHYS CHILENSIS (CHONDRICHTHYES, ELASMOBRANCHII, SCYLIORHINIDAE) AS NON DESTRUCTIVE INDICATOR OF CONTAMINATION

Silva, Víctor; Valenzuela, Ariel; Ruiz, Paulo; Oyarzún, Ciro
2005-01-01

Resumen en español La contaminación de las zonas costeras por la actividad humana es un problema que se ha incrementado en Chile, siendo caleta Lenga una de las zonas más contaminadas del país. Debido a la presencia de tripanosomas y eosinofilia descritas previamente en pintarroja, Schroederichthys chilensis (Guichenot 1848), se desarrolló un método para cuantificar Trypanosoma humboldti (Morillas et al. 1987) con el fin de disponer de una estrategia no destructiva para evaluar contami (mas) nación química. Para ello se obtuvo sangre de pintarroja en Dichato (zona control) y en Lenga (zona problema) durante los meses de septiembre y octubre de 2003 y se cuantificó el hemoparásito utilizando cámaras Kova. El conteo de tripanosomas fue menor en Lenga (5,7 tripanosomas/ml) respecto de la zona control (9,1 tripanosomas/ml; p=0,0007); a su vez, los eosinófilos/ml fueron menores en Lenga (6.494 células/ml vs 8.226 células/ml; p=0,027 respectivamente). Se postula que el menor conteo de tripanosomas en Lenga se debería al daño celular producido por la contaminación química. La estandarización del método para cuantificar tripanosomas proveería de una herramienta efectiva para identificar zonas con distinto grado de contaminación y una forma de utilizar a la pintarroja como un bioindicador de contaminación química sin la necesidad de sacrificar al pez, pudiendo constituirse en un biomarcador a incorporar en los programas de monitoreo ambiental Resumen en inglés Chemical pollution in coastal areas is an important and increasing problem in Chile. Lenga's area is one of the most polluted zones in Chile. In order to develop a non destructive pollution instrument, samples of blood of catsharks Schroederichthys chilensis (Guichenot 1848) both from Dichato (control zone) and Lenga (problem zone) were obtained between September and October 2003 (20 individuals in each zone). The blood parasites Trypanosoma humboldti (Morillas et al. 198 (mas) 7) were determined in a Kova camera. The amount of trypanosomes in Lenga (5,7 trypanosomes/ml) was lesser than the control zone (9,1 trypanosomes/ml; p=0.0007). The eosinophills were also fewer in Lenga (6.494 cells/ml) than Dichato (8.226 cells/ml; p=0.027). We hypothesize that minor counts of trypanosomes in Lenga could be explained by the cell damage produced by chemical pollution. The standardization procedure done for the method to quantify trypanosomes allowed a very effective tool in order to identify zones with different grade of pollution and also serves for utilizing the Chilean catshark as bioindicator of chemical pollution without killing the fish

Scientific Electronic Library Online (Spanish)

4

Selective destruction of tumor cells through specific inhibition of products resulting from chromosomal translocations

Rodríguez-García, A.; Sánchez-Martín, M.; Pérez-Losada, J.; Pérez-Mancera, P. A.; Sagrera, A.; Cobaleda, C.; Sánchez-García, I.; Gutiérrez-Cianca, N.
2001-01-01

Digital.CSIC (Spain)

5

Rapid cell variation can determine the establishment of a persistent viral infection

Martín-Hernández, Ana M.; Carrillo, Elisa C.; Sevilla, Noemí; Domingo, Esteban
1994-01-01

Digital.CSIC (Spain)

7

Perkinsosis in molluscs: A review

Villalba, Antonio; Reece, Kimberly S.; Ordás, M. Camino; Casas, Sandra M.; Figueras, Antonio
2004-01-01

Digital.CSIC (Spain)

8

Molecular basis for a lack of correlation between viral fitness and cell killing capacity

Herrera, Mónica ; García-Arriaza, Juan ; Pariente, Nonia ; Escarmis, Cristina ; Domingo, Esteban

[Abstract] The relationship between parasite fitness and virulence has been the object of experimental and theoretical studies often with conflicting conclusions. Here, we provide direct experimental evidence that viral fitness and virulence, both measured in the same biological environment provided...

DRIVER (Spanish)

9

Molecular basis for a lack of correlation between viral fitness and cell killing capacity

Herrera, Mónica; García-Arriaza, Juan; Pariente, Nonia; Escarmis Homs, Cristina; Domingo, Esteban
2007-04-13

Digital.CSIC (Spain)

10

Methods employing bacterial ParD kis/ParD kid toxin-antitoxin system for killing eukaryotic cells

Cueva Méndez, Guillermo de la ; Laskey, Ronald A. ; Mills, Anthony D. ; Díaz-Orejas, Ramón

Filing Date: 2000-07-17.-- Priority Data: GB 9916810 (1999-07-16). | The present invention relates to killing cells, or at least impeding cell cycle progression. More particularly it relates to methods and means for attacking eukaryotic cells, such as tumour cells, with cytostatic, cytotoxic and/or ...

DRIVER (Spanish)

11

Methods employing bacterial ParD kis/ParD kid toxin-antitoxin system for killing eukaryotic cells

Cueva Méndez, Guillermo de la; Laskey, Ronald A.; Mills, Anthony D.; Díaz-Orejas, Ramón
2007-09-26

Digital.CSIC (Spain)

12

Macrophage elastase kills bacteria within murine macrophages

McGarry Houghton, A.; Hartzell, William O.; Robbins, Clinton S.; Gomis-Rüth, F. Xavier; Shapiro, Steven D.
2009-06-17

Digital.CSIC (Spain)

13

Lytic activity of the recombinant staphylococcal bacteriophage ΦH5 endolysin active against Staphylococcus aureus in milk

Obeso Díaz, José María; Martínez Fernández, Beatriz; Rodríguez González, Ana; García Suárez, María Pilar
2008-01-01

Digital.CSIC (Spain)

16

Intracellular Triggering of Fas Aggregation and Recruitment of Apoptotic Molecules into Fas-enriched Rafts in Selective Tumor Cell Apoptosis

Gajate, Consuelo ; Canto-Jañez, Esther del ; Acuña Fernandez, Alberto Ulises ; Amat-Guerri, Francisco ; Emilio Geijo, Emilio

We have discovered a new and specific cell-killing mechanism mediated by the selective uptake of the antitumor drug 1-O-octadecyl-2-O-methyl-rac-glycero-3-phosphocholine (ET-18-OCH3, Edelfosine) into lipid rafts of tumor cells, followed by its coaggregation with Fas death receptor (also known as APO...

DRIVER (Spanish)

17

Intracellular Triggering of Fas Aggregation and Recruitment of Apoptotic Molecules into Fas-enriched Rafts in Selective Tumor Cell Apoptosis

Gajate, Consuelo; Canto-Jañez, Esther del; Acuña Fernandez, Alberto Ulises; Amat-Guerri, Francisco; Emilio Geijo, Emilio; Santos-Beneit, Antonio M.; Veldman, Robert J.; Mollinedo, Faustino
2004-08-02

Digital.CSIC (Spain)

18

Increased sensitivity to oxidative injury in chinese hamster ovary cells stably transfected with rat liver S-adenosylmethionine synthetase cDNA

Sánchez-Góngora, Estrella; Pastorino, John G.; Álvarez, Luis; Pajares, María A.; García, Concepción; Viña, Juan R.; Mato, José M.; Farber, John L.
1996-11-01

Digital.CSIC (Spain)

19

IL-2 protects T cell hybrids from the cytolytic effect of glucocorticoids. Synergistic effect of IL-2 and dexamethasone in the induction of high-affinity IL-2 receptors

Fernández-Ruiz, E.; Rebollo, A.; Nieto, M. Ángela; Sanz, E.; Somoza, C.; Ramírez, F.; López-Rivas, A.; Silva González, Augusto
1989-01-01

Digital.CSIC (Spain)

20

Hydrogen Peroxide Effects on the Quality of Chilled Carrot

De la Plaza, José L.; Gómez, Rosario; Gonzalo, Ana M.
2006-01-01

Digital.CSIC (Spain)

21

Evaluation of Immunomodulatory Effects of Lactic Acid Bacteria in Turbot (Scophthalmus maximus)

Villamil, L.; Tafalla, Carolina; Figueras, Antonio; Novoa, Beatriz
2002-11-01

Digital.CSIC (Spain)

22

Etica científica y embriones congelados/ Scientific ethics and frozen embryos

Valenzuela, Carlos Y
2001-05-01

Resumen en inglés Background: Scientific Ethics is the theory and praxis of decisions. Philosophical Ethics is presented as the theory and praxis of the good. As the good differs among cultures, Philosophical Ethics is dependent on the endo-cultural good conception. The decision (included that one of adhesion or not to a world vision) depends on neuro-psychic specific factors: i) cognitive factors that include mostly the knowledge of the alternatives and their consequences and the ideologi (mas) cal or religious conception of good in relation to the alternatives; ii) affective factors that make alternatives pleasant, unpleasant or neutral, attractive, repulsive or neutral; iii) emotional factors that associate to alternatives anger, peace or neutrality, sadness, happiness or neutrality; iv) value factors that assign importance, triviality or neutrality to alternatives, or assign them significance, irrelevancy or neutrality. There are unspecific factors such as the psychic energy, desire or others. Mixed factors such as attitude, motivation, intention and others. Scientific Ethics deals with the mind as a materio-energetic process which is different from the soul, eggs and embryos of any species are full individuals of that species, because, they have initiated a copy of their genome that specify, give autonomy and define them as individuals. For Scientific Ethics to leave frozen embryos like that for ever, to defrost and get rid of them or to use their cells for science are synonymous of killing them. To defrost them to use their cells as stem cells for somatic cell therapy or to implant them into uteri to continue their development is to maintain alive their cells, but only the implantation allows their maintenance as individuals, thus, being the only compatible with the Christian ethics. The compatibility of these alternatives with other ethics is discussed (Rev Méd Chile 2001; 129: 561-8)

Scientific Electronic Library Online (Spanish)

23

Dissection of Host Cell Signal Transduction during Acinetobacter baumannii – Triggered Inflammatory Response

Bengoechea, José Antonio; March, Catalina; Llobet Brossa, Enrique; Garmendia, Junkal; Regueiro, Verónica; Moranta, David; Morey, Pau
2010-04-07

Digital.CSIC (Spain)

24

Degradation of 16S rRNA and attributes of viability of viable but nonculturable probiotic bacteria

Lahtinen, Sampo; Ahokoski, H.; Reinikainen, Johanna P.; Gueimonde Fernández, Miguel; Nurmi, J.; Ouwehand, Arthur C.; Salminen, Seppo
2008-04-28

Digital.CSIC (Spain)

25

Choline kinase alpha depletion selectively kills tumoral cells

Báñez Coronel, Mónica; Ramírez de Molina, Ana; Rodriguez-Gonzalez, Agustin; Sarmentero, Jacinto; Ramos, Mª Angeles; Garcia-Cabezas, Miguel Angel; Garcia-Oroz, Lourdes; Lacal, Juan Carlos
2008-12-01

Digital.CSIC (Spain)

26

Caspase-1 as a radio- and chemo-sensitiser in vitro and in vivo

Martín-Duque, Pilar; Quintanilla Ávila, Miguel; McNeish, Iain; Lopes, Rita; Romero, Jesús; Romero, Diana; Lemoine, Nick R.; Ramón y Cajal, Santiago; Vassaux, Georges
2006-05-01

Digital.CSIC (Spain)

28

Apoptosis in human thymocytes after treatment with glucocorticoids

Nieto, M. Ángela; González, A.; Gambón, F.; Díaz-Espada, F.; López-Rivas, Abelardo
1992-05-01

Digital.CSIC (Spain)

29

Antimicrobial peptides: To membranes and beyond

Marcos López, José Francisco; Gandía Gómez, Mónica
2009-06-01

Digital.CSIC (Spain)

32

A moderate and transient deficiency of maternal thyroid function at the beginning of fetal neocorticogenesis alters neuronal migration

Ausó Monreal, Eva; Lavado Autric, Rosalía; Cuevas, Estela; Escobar del Rey, Francisco; Morreale de Escobar, Gabriella; Berbel Navarro, Pere
2004-09-01

Digital.CSIC (Spain)