Sample records for MALIGNITAET (BOESARTIGKEIT) (malignancies)
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2

Untersuchung möglicher immunologischer Zielstrukturen für eine adjuvante Therapie des operablen Plattenepithelkarzinoms des Ösophagus

Siegmund, Annika

Einleitung: Ösophaguskarzinome haben generell eine schlechte Prognose und der Nutzen der derzeitig verfügbaren adjuvanten Therapien wird nach wie vor kontrovers diskutiert. Aufgabe dieser Arbeit war die Expressionsanalyse zweier möglicher immunologischer Zielstrukturen für eine adjuvante Therapie de...

DRIVER (German)

28
87

Comparison between antithymocyte globulin and alemtuzumab and the possible impact of KIR-ligand mismatch after dose-reduced conditioning and unrelated stem cell transplantation in patients with multiple myeloma

Kroger, N; Shaw, B; Iacobelli, S; Zabelina, T; Peggs, K; Shimoni, A; Nagler, A; Binder, T; Eiermann, T; Madrigal, A; Schwerdtfeger, R

We compared antithymocyte globulin (ATG) with alemtuzumab in 73 patients with multiple myeloma, who underwent reduced conditioning with melphalan/fludarabine, followed by allogencic stem cell transplantation from human leucocyte antigen-matched or -mismatched unrelated donors. The ATG group had more...

DRIVER (German)

98

Arylamine N-acetyltransferase (NAT2) mutations and their allelic linkage in unrelated Caucasian individuals: correlation with phenotypic activity.

Maurer, A; Cascorbi, I; Brockmöller, J; Drakoulis, N; Sperling, K; Roots, I

The polymorphic arylamine N-acetyltransferase (NAT2; EC 2.3.1.5) is supposed to be a susceptibility factor for several drug side effects and certain malignancies. A group of 844 unrelated German subjects was genotyped for their acetylation type, and 563 of them were also phenotyped. Seven mutations ...

DRIVER (German)