Sample records for LACTAME (lactams)
from WorldWideScience.org

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7

Synthesis of 4-Dendronized β-Lactams

Díez-Barra, Enrique; García-Martínez, Joaquín C.; Rodríguez-López, Julián
2003-01-01

German National Library of Science and Technology (GetInfo) (German)

8

Synthesis of 4-Dendronized β-Lactams

Díez-Barra, Enrique; García-Martínez, Joaquín C.; Rodríguez-López, Julián
2003-01-01

German National Library of Science and Technology (GetInfo) (German)

78

OXA-24, a Novel Class D β-Lactamase with Carbapenemase Activity in an Acinetobacter baumannii Clinical Strain

Bou, Germán; Martínez-Beltrán, Jesús; Oliver, Antonio

Acinetobacter baumannii RYC 52763/97, a clinical isolate involved in a prolonged nosocomial outbreak at our hospital, was resistant to all β-lactams tested, including imipenem and meropenem, which had MICs of 128 and 256 μg/ml, respectively. This strain synthesized three β-lactamases: a plasmid-medi...

DRIVER (German)

79

Crystal structure of the carbapenemase OXA-24 reveals insights into the mechanism of carbapenem hydrolysis

Romero, Antonio; Santillana, Elena; Bou, Germán; Beceiro, Alejandro

Combating bacterial resistance to β-lactams, the most widely used antibiotics, is an emergent and clinically important challenge. OXA-24 is a class D β-lactamase isolated from a multiresistant epidemic clinical strain of Acinetobacter baumannii. We have investigated how OXA-24 specifically hydrolyze...

DRIVER (German)