Sample records for BLUT (blood)
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35

Toxikokinetische Betrachtungen zu 2,3,7,8-Tetrachlordibenzo-p-dioxin Toxicokinetic aspects of 2,3,7,8-tetrachlorodibenzo-p-dioxin

Wirsing, Johann Michael

Die vorliegende Arbeit zielte zum einen auf die Erarbeitung und Validierung von Methoden zur experimentellen Messung von Blut-Gewebe-Verteilungskoeffizienten und Extraktionseffizienz-Koeffizienten zur Beschreibung der Verteilung von 2,3,7,8-Tetrachlordibenzo-p-dioxin (TCDD). Diese Parameter finden E...

DRIVER (German)

36

Überblick zur globalen Verbreitung der Tularämie und seroepidemiologische Untersuchung zur menschlichen Prävalenz von Francisella tularensis in Deutschland Overview regarding the global distribution of tularemia and a seroepidemiological survey concerning the prevalence of Francisella tularensis within the German population.

Priebe, Heidi-Sabrina

Francisella tularensis ist trotz seines hohen pathogenen Potentials ein in Deutschland weitestgehend unbekannter Erreger. Anhand von Serumproben aus dem Bundes-Gesundheitssurvey des Robert Koch-Institutes konnte eine Seroprävalenz für Deutschland von 0,2 % ermittelt werden. In einem anschließenden e...

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40

Value of PCR for Detection of Toxoplasma gondii in Aqueous Humor and Blood Samples from Immunocompetent Patients with Ocular Toxoplasmosis

Navas, Enrique; Bou, Germán; Martí-Belda, Paloma; Figueroa, Marta S.; Guerrero, Antonio

Toxoplasma gondii infection is an important cause of chorioretinitis in the United States and Europe. Most cases of Toxoplasma chorioretinitis result from congenital infection. Patients are often asymptomatic during life, with a peak incidence of symptomatic illness in the second and third decades o...

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41

Untersuchung frühzeitiger Reaktionen lymphozytärer Proteine auf γ-Bestrahlung humanen Vollbluts und deren Dosisabhängigkeit – Voraussetzung für die Entwicklung eines individuellen strahlenbiologischen Dosimeters Early response of lymphocyte proteins after γ-irradiation of human whole blood and their dose-dependence – prerequisite for the development of individual biodosimeter

Turtoi, Andrei

The present thesis is concerned with the issues involved in obtaining reliable experimental data permitting a retrospective assessment of radiation-induced doses at the time of application or contamination.In order to provide prompt medical treatment of those injured in accidents with ionizing radi...

DRIVER (German)

43

The first demonstration of lactic acid in human blood in shock by Johann Joseph Scherer (1814–1869) in January 1843

Bakker, J.; Kompanje, E. J.O.; van der Hoven, B.; Jansen, T. C.

Lactic acid was first found and described in sour milk by Karl Wilhelm Scheele (1742–1786) in 1780. The German physician–chemist Johann Joseph Scherer (1841–1869) demonstrated the occurrence of lactic acid in human blood under pathological conditions in 1843 and 1851. In this article we honour the f...

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44

The Kallikrein-Related Peptidases hK2 and PSA with Emphasis on Genetic Variation, Secretion, and Sperm Motility

Sävblom, Charlotta

Prostate-specific antigen (PSA) and human glandular kallikrein 2 (hK2) are secreted by the prostate into seminal plasma and through leakage into blood. This leakage increases rapidly in prostate disease, and PSA is used worldwide as a marker of prostate cancer. PSA is activated in vitro by hK2, and ...

DRIVER (German)

47

Stable isotopes and mercury in blood of harbour seals (Phoca vitulina) caught on a German sandbank

Di-Poi, C.; Siebert, Ursula; Drouguet, Olivier; Fonfara, S.; Lepoint, Gilles; Das, Krishna

19th conference of the European Cetacean Society 2nd-7th April 2005 La Rochelle France More than 21 500 harbour seals were killed by Phocine Distempter Virus in the North Sea and adjacent waters in 2002. After the second seal die-off had ceased, seals were captured alive (and then released) on a sandban...

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48

Somatic intragenic recombination within the mutated locus BLM can correct the high sister-chromatid exchange phenotype of Bloom syndrome cells.

Alhadeff, B; Ellis, N A; Proytcheva, M; Lennon, D J; Henderson, E E; German, J

Cells from persons with Bloom syndrome feature an elevated rate of sister-chromatid exchange (SCE). However, in some affected persons a minority of blood lymphocytes have a normal SCE rate. Persons who inherit the Bloom syndrome gene BLM identical by descent from a common ancestor very rarely exhibi...

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49

Rhinitis/Bronchopneumonia syndrome in Irish Wolfhounds.

Clercx, Cécile; Reichler, I; Peeters, Dominique; Mc Entee, Kathleen; German, A; Detilleux, Johann; Schynts, E; Schaaf, Nicole

This study describes the clinical, immunologic, genetic, and pathologic features of Irish Wolfhounds with rhinitis/bronchopneumonia syndrome. The dogs examined were from Belgium, The Netherlands, UK, Canada, Germany, and Switzerland. Signs included transient to persistent mucoid or mucopurulent rhin...

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50

Reduction of performance time for microbial respiration in the context of on-site analysis: SETAC German Language Branch. Poster zur 8. Tagung "New Blood in Ecotoxicology", Heidelberg, 21-23. September 2003

Simon, M.; Hund-Rinke, K.

The microbial respiration activity in soil can be used as an indicator for the presence of toxic substances and easily degradable carbon sources. If standardized methods are applied, the preparation of samples (sieving, determination of maximum water holding capacity, determination and adjustment of...

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58

Nationwide German Multicenter Study on the Prevalence of Antibiotic Resistance in Streptococcal Blood Isolates from Neutropenic Patients and Comparative In Vitro Activities of Quinupristin-Dalfopristin and Eight Other Antimicrobials

Peters, Georg; Schorn, Holger; Brauers, Johannes; Reinert, Ralf René; Kresken, Michael; von Eiff, Christof; Hafner, Dieter

In a prospective multicenter study (1996 to 1999), 156 episodes of bacteremic streptococcal infections of neutropenic patients were evaluated. Streptococcus oralis (26.3%), S. pneumoniae (26.3%), S. agalactiae (11.5%), S. mitis (9%), and S. pyogenes (5.8%) were the predominant species. Four strains ...

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61

Molekulare Analyse von Tumorsuppressorgen-Kandidaten auf Chromosom 10 in Tumoren des Nervensystems

Köhler, Benjamin

Deletionen des Chromosoms 10 stellen eine häufige Veränderung in unterschiedlichen Tumoren des Nervensystems dar. Sie finden sich u.a. in der Mehrzahl der Glioblastome, aber auch in Subgruppen von atypischen und anaplastischen Meningeomen sowie Medulloblastomen. Der häufige Verlust von genetischem M...

DRIVER (German)

62

Molekularbiologische Analysen der Resistenzmechanismen Makrolid-resistenter Staphylococcus aureus Isolate

Petridu, Jasmina

Die vorliegende Arbeit zur molekularbiologischen Analyse derResistenzmechanismen Makrolidresistenter Staphylococcus aureus Isolaten gliedert sich in 5 Teile: Im ersten Teil der vorliegenden Arbeit wurde die Epidemiologie der Resistenzmechanismen untersucht, d.h. die Verbreitung und Häufigkeit d...

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63

Molecular characterization of a novel form of (A gamma delta beta)zero-thalassemia deletion with a 3' breakpoint close to those of HPFH-3 and HPFH-4: insights for a common regulatory mechanism.

Stamatoyannopoulos, G; Anagnou, N P; Nienhuis, A W; Papayannopoulou, T

We have molecularly characterized a novel (A gamma delta beta)zero-thalassemia associated with increased synthesis of HbF in three members of a German family. The levels of HbF in the peripheral blood red cells of the heterozygotes ranged between 9.9% and 12.5% with a heterocellular distribution in ...

DRIVER (German)

71

Medizinische und ökonomische Aspekte der präoperativen Eigenblutspende in der Herzchirurgie Medical and economic aspects of preoperative autologous blood donation in cardiac surgery

Heyde, Sophie

Es wurden Daten von 3031 Patienten des Deutschen Herzzentrums München untersucht. Bei Patienten, die kein Eigenblut spendeten, betrug die Inzidenz homologer Transfusionen 64%. Diese konnte durch die Spende von durchschnittlich 2,5 Einheiten Eigenblut auf 16% reduziert werden. Pro Eigenblutspender wu...

DRIVER (German)

77

Kontrollierte, doppelblinde Studie zur Therapiequalität einer Insulin-Pumpentherapie mit Insulin Lispro

Jatzkowski, Eva

Kontrollierte, doppelblinde Studie zur Therapiequalität einer Insulin-Pumpentherapie mit Insulin LisproVom Jahresende 2000 bis zum Februar 2002 führten wir eine monozentrische randomisierte doppelblinde Studie im Cross-over-Design mit 27 Typ-I-Diabetikern über einen Zeitraum von 12 Monaten durch. ...

DRIVER (German)

80

Intra- and extragenic marker haplotypes of CFTR mutations in cystic fibrosis families

Dork, T; Neumann, T; Wulbrand, U; Wulf, B; Kalin, N; Maaß, G; Krawczak, M; Guillermit, H; Ferec, C; Horn, G; Klinger, K; Kerem, B

In order to facilitate the screening for the less common mutations in the cystic fibrosis (CF) gene viz., the CF transmembrane conductance regulator gene (CFTR), marker haplotypes were determined for German non-CF (N) and CF chromosomes by polymerase chain reaction analysis of four polymorphisms ups...

DRIVER (German)

81

Increased Prevalence of Class I Integrons in Escherichia coli, Klebsiella Species, and Enterobacter Species Isolates over a 7-Year Period in a German University Hospital

Follmann, Patrick; Schmitz, Franz-Josef; Geisel, Roland; Hafner, Dieter; Kirschke, Christian; Fluit, Ad C.; Verhoef, Jan

The prevalence of integrons in five enterobacterial species was analyzed in 900 blood culture isolates from 1993, 1996, and 1999. Remarkably, the prevalence increased from 4.7% in 1993 to 9.7% in 1996 and finally to 17.4% in 1999 (P < 0.01). Within 7 years the combined percentage of P1 strong pro...

DRIVER (German)

87

GENERAL ORAL GLUCOSE TOLERANCE TEST DURING PREGNANCY, AN OPPORTUNITY FOR IMPROVED PREGNANCY OUTCOME AND IMPROVED FUTURE HEALTH.

Anderberg, Eva

Gestational diabetes mellitus (GDM) is associated with a risk of adverse pregnancyoutcome and is a predictor of subsequent diabetes. The aims of this work were todescribe a reliable routine to diagnose abnormal glucose tolerance during pregnancy,to investigate women’s opinions of the specialist c...

DRIVER (German)

90

Experimental treatment of stroke in spontaneously hypertensive rats by CD34+ and CD34- cord blood cells

Boltze, J.; Kowalski, I.; Geiger, K.; Reich, D.; Gunther, A.; Buhrle, C.; Egger, D.; Kamprad, M.; Emmrich, F.

Obwohl humanes Nabelschnurblut als Quelle von Stammzellen für experimentelle Therapien von Erkrankungen des Zentralnervensystems derzeit intensiv untersucht wird, ist noch wenig über die zellulären Prozesse bekannt, die der funktionellen Verbesserung von Ausfallerscheinungen zugrunde liegen. In der ...

DRIVER (German)

91

Evidence for increased in vivo mutation and somatic recombination in Bloom's syndrome.

German, J; Langlois, R G; Jensen, R H; Bigbee, W L

The glycophorin A assay was used to estimate the frequency of mutations that accumulate in vivo in somatic cells of persons with Bloom's syndrome (BS). This assay measures the frequency in persons of blood type MN of variant erythrocytes that lack the expression of one allelic form of glycophorin A,...

DRIVER (German)

94

Effektausprägungen von Umweltchemikalien auf aquatische Testorganismen in Abhängigkeit der Sauerstoffsättigung von Wasserproben: SETAC German Language Branch. Poster zur 8. Tagung "New Blood in Ecotoxicology", Heidelberg, 21-23. September 2003

Hörner, J.; Hund-Rinke, K.; Schäffer, A.

Zur Erfassung und Bewertung des bioverfügbaren Anteils von Umweltchemikalien in Bodeneluaten, Sicker- und Grundwasserproben werden Ökotoxizitätstests mit aquatischen Testorganismen angewendet. Um optimale Testbedingungen für die Organismen zu schaffen, werden die Untersuchungen bei Sauerstoffsättigu...

DRIVER (German)

106

Depletion of Resident Chlamydia pneumoniae through Leukoreduction by Filtration of Blood for Transfusion

Yamamoto, Yoshimasa; Ikejima, Hideaki; Leparc, German F.; Friedman, Herman

Current studies indicate that a significant percentage of healthy blood donors carry Chlamydia pneumoniae in their blood. Although the clinical significance of such findings is unknown, eradication of such bacteria from blood components may contribute to transfusion safety. Deletion of C. pneumoniae...

DRIVER (German)

112

Comparison between antithymocyte globulin and alemtuzumab and the possible impact of KIR-ligand mismatch after dose-reduced conditioning and unrelated stem cell transplantation in patients with multiple myeloma

Kroger, N; Shaw, B; Iacobelli, S; Zabelina, T; Peggs, K; Shimoni, A; Nagler, A; Binder, T; Eiermann, T; Madrigal, A; Schwerdtfeger, R

We compared antithymocyte globulin (ATG) with alemtuzumab in 73 patients with multiple myeloma, who underwent reduced conditioning with melphalan/fludarabine, followed by allogencic stem cell transplantation from human leucocyte antigen-matched or -mismatched unrelated donors. The ATG group had more...

DRIVER (German)

113

Calcium metabolism and breast cancer risk

Almquist, Martin

Emerging evidence suggests that calcium and its regulating hormones, i.e. vitamin D and parathyroid hormone (PTH), affect breast cancer risk. The associations between serum calcium levels and breast cancer risk, between serum calcium levels and known risk factors of breast cancer, and between serum...

DRIVER (German)

117

Bloom's syndrome. IV. Sister-chromatid exchanges in lymphocytes.

Chaganti, R S; German, J; Louie, E; Schonberg, S

An abnormally great amount of exhange between both sister and nonsister-but-homologous chromatids is a highly characteristic feature of cultured blood lymphocytes from individuals with Bloom's syndrome. However, a population of lymphocytes which exhibit a normal amount of exchange can be detected in...

DRIVER (German)

118
119

Blood pressure reduction with olmesartan in mild-to-moderate essential hypertension: a planned interim analsis of an open label sub-study in German patients

Barrios, Vivencio; Böhm, Michael; Boccanelli, Alessandro; Ewald, Silke; Girerd, Xavier; Heagerty, Anthony; Krzesinski, Jean-Marie

Objective : To present the baseline characteristics and open-label treatment phase results for German patients in OLMEBEST, a European, multinational, partially randomized, partially double-blind study in patients with mild-to-moderate essential hypertension. Research design an methods: after a 2-w...

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120

Blood glucose and risk of incident and fatal cancer in the metabolic syndrome and cancer project (Me-Can) : analysis of six prospective cohorts.

Stocks, Tanja; Rapp, Kilian; Bjorge, Tone; Manjer, Jonas; Ulmer, Hanno; Selmer, Randi; Lukanova, Annekatrin; Johansen, Dorthe

 BackgroundProspective studies have indicated that elevated blood glucose levels may increase the risk of cancer, but the strength of the association is unclear. We examined the association between blood glucose and cancer risk in a prospective study of six European cohorts. Methods... Repository : View repository documents , Publikationer från Umeå Universitet

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131

Alcohol Use in Swedish Halls of Residence

Ståhlbrandt, Henrietta

In the year 2000, the alcohol habits of 1460 Swedish university students living in residence halls were assessed. The students had a mean age of 23.8 years, and 64% were male. The results from this baseline assessment show that the mean AUDIT score (± sd) was 10.3 ± 5.2 for males and 8.1 ± 4.7 for f...

DRIVER (German)

133

ASPECTS OF FLUID THERAPY: An experimental study of the effects of systemic inflammation, microvascular permeability, blood pressure and plasma volume

Dubniks, Maris

Adequate circulating blood volume is a prerequisite for circulatory stability. Fluid therapy aims at correcting hypovolaemia, and is an important part of the haemodynamic management of perioperative and critically ill patients. The efficacy of plasma volume substitution largely depends on the pharma...

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134

Howlett, William P.

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135

Howlett, Peter; Broadberry, Stephen

In 20 papers from the fifth and final sitting of a conference series on total war, August 2001 in Hamburg, European and North American historians focus on World War II as total war. This war was characterized as the paradigm for total war when the notion was first introduced. They consider the dimen...

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