Sample records for BIOLOGISCHE WIRKUNGEN (biological effects)
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45

The Kallikrein-Related Peptidases hK2 and PSA with Emphasis on Genetic Variation, Secretion, and Sperm Motility

Sävblom, Charlotta

Prostate-specific antigen (PSA) and human glandular kallikrein 2 (hK2) are secreted by the prostate into seminal plasma and through leakage into blood. This leakage increases rapidly in prostate disease, and PSA is used worldwide as a marker of prostate cancer. PSA is activated in vitro by hK2, and ...

DRIVER (German)

46

Structural Features of Φ 29 Single-stranded DNA-binding Protein: II. global conformation of Φ 29 single-stranded dna-binding protein and the effects of complex formation on the protein and the single-stranded DNA

Soengas, María S. ; Reyes Mateo, C. ; Rivas, Germán ; Salas, Margarita ; Acuña Fernandez, Alberto Ulises

The strand-displacement mechanism of Bacillus subtilis phage Φ29 DNA replication occurs through replicative intermediates with high amounts of single-stranded DNA (ssDNA). These ssDNA must be covered by the viral ssDNA-binding protein, Φ29 SSB, to be replicated in vivo. To understand the characteris...

DRIVER (German)

54

Psychotic disorders in the Lundby population 1947-1997: Incidence, life-time prevalence and predictors related to personality and behaviour

Bogren, Mats

The aims were to analyze the first incidence, age-at-onset, prevalence and personality related predictors of psychotic disorders in the Lundby population (n=3563) – a community population followed through four waves of field study 1947-1997.Case ascertainment included interviews, registers, case n...

DRIVER (German)

85

ECNIS-sponsored workshop on biomarkers of exposure and cancer risk: DNA damage and DNA adduct detection and 6th GUM-32P-postlabelling workshop, German Cancer Research Center, Heidelberg, Germany, 29-30 September 2006.

Arlt, Volker M.; Frei, Eva; Schmeiser, Heinz H.

Of all the chemicals classified as carcinogenic to humans by the International Agency for Research on Cancer (IARC), 90% exert their biological effects through binding of their metabolically activated intermediates to DNA forming covalent DNA adducts. As a consequence DNA adducts are generally consi...

DRIVER (German)

91

Children's Gestures from 18 to 30 months

Andrén, Mats

This thesis concerns the nature of the gestures performed by five Swedish children. The children are followed from 18 to 30 months of age: an age range which is characterized by a rapid succession of developmental changes in children's abilities to communicate by means of both spoken language and ge...

DRIVER (German)

93

Calcium metabolism and breast cancer risk

Almquist, Martin

Emerging evidence suggests that calcium and its regulating hormones, i.e. vitamin D and parathyroid hormone (PTH), affect breast cancer risk. The associations between serum calcium levels and breast cancer risk, between serum calcium levels and known risk factors of breast cancer, and between serum...

DRIVER (German)