Convergent Evolution of Hemoglobin Function in High-Altitude Andean Waterfowl Involves Limited Parallelism at the Molecular Sequence Level.

Directory of Open Access Journals (Sweden)

Chandrasekhar Natarajan

2015-12-01

Full Text Available A fundamental question in evolutionary genetics concerns the extent to which adaptive phenotypic convergence is attributable to convergent or parallel changes at the molecular sequence level. Here we report a comparative analysis of hemoglobin (Hb function in eight phylogenetically replicated pairs of high- and low-altitude waterfowl taxa to test for convergence in the oxygenation properties of Hb, and to assess the extent to which convergence in biochemical phenotype is attributable to repeated amino acid replacements. Functional experiments on native Hb variants and protein engineering experiments based on site-directed mutagenesis revealed the phenotypic effects of specific amino acid replacements that were responsible for convergent increases in Hb-O2 affinity in multiple high-altitude taxa. In six of the eight taxon pairs, high-altitude taxa evolved derived increases in Hb-O2 affinity that were caused by a combination of unique replacements, parallel replacements (involving identical-by-state variants with independent mutational origins in different lineages, and collateral replacements (involving shared, identical-by-descent variants derived via introgressive hybridization. In genome scans of nucleotide differentiation involving high- and low-altitude populations of three separate species, function-altering amino acid polymorphisms in the globin genes emerged as highly significant outliers, providing independent evidence for adaptive divergence in Hb function. The experimental results demonstrate that convergent changes in protein function can occur through multiple historical paths, and can involve multiple possible mutations. Most cases of convergence in Hb function did not involve parallel substitutions and most parallel substitutions did not affect Hb-O2 affinity, indicating that the repeatability of phenotypic evolution does not require parallelism at the molecular level.

Convergence Analysis for the Multiplicative Schwarz Preconditioned Inexact Newton Algorithm

KAUST Repository

Liu, Lulu

2016-10-26

The multiplicative Schwarz preconditioned inexact Newton (MSPIN) algorithm, based on decomposition by field type rather than by subdomain, was recently introduced to improve the convergence of systems with unbalanced nonlinearities. This paper provides a convergence analysis of the MSPIN algorithm. Under reasonable assumptions, it is shown that MSPIN is locally convergent, and desired superlinear or even quadratic convergence can be obtained when the forcing terms are picked suitably.

Convergence Analysis for the Multiplicative Schwarz Preconditioned Inexact Newton Algorithm

KAUST Repository

Liu, Lulu; Keyes, David E.

2016-01-01

The multiplicative Schwarz preconditioned inexact Newton (MSPIN) algorithm, based on decomposition by field type rather than by subdomain, was recently introduced to improve the convergence of systems with unbalanced nonlinearities. This paper provides a convergence analysis of the MSPIN algorithm. Under reasonable assumptions, it is shown that MSPIN is locally convergent, and desired superlinear or even quadratic convergence can be obtained when the forcing terms are picked suitably.

Role and convergent evolution of competing RNA secondary structures in mutually exclusive splicing.

Science.gov (United States)

Yue, Yuan; Hou, Shouqing; Wang, Xiu; Zhan, Leilei; Cao, Guozheng; Li, Guoli; Shi, Yang; Zhang, Peng; Hong, Weiling; Lin, Hao; Liu, Baoping; Shi, Feng; Yang, Yun; Jin, Yongfeng

2017-10-03

Exon or cassette duplication is an important means of expanding protein and functional diversity through mutually exclusive splicing. However, the mechanistic basis of this process in non-arthropod species remains poorly understood. Here, we demonstrate that MRP1 genes underwent tandem exon duplication in Nematoda, Platyhelminthes, Annelida, Mollusca, Arthropoda, Echinodermata, and early-diverging Chordata but not in late-diverging vertebrates. Interestingly, these events were of independent origin in different phyla, suggesting convergent evolution of alternative splicing. Furthermore, we showed that multiple sets of clade-conserved RNA pairings evolved to guide species-specific mutually exclusive splicing in Arthropoda. Importantly, we also identified a similar structural code in MRP exon clusters of the annelid, Capitella teleta, and chordate, Branchiostoma belcheri, suggesting an evolutionarily conserved competing pairing-guided mechanism in bilaterians. Taken together, these data reveal the molecular determinants and RNA pairing-guided evolution of species-specific mutually exclusive splicing spanning more than 600 million years of bilaterian evolution. These findings have a significant impact on our understanding of the evolution of and mechanism underpinning isoform diversity and complex gene structure.

Mechanical basis of morphogenesis and convergent evolution of spiny seashells

KAUST Repository

Chirat, R.; Moulton, D. E.; Goriely, A.

2013-01-01

Convergent evolution is a phenomenon whereby similar traits evolved independently in not closely related species, and is often interpreted in functional terms. Spines in mollusk seashells are classically interpreted as having repeatedly evolved as a defense in response to shell-crushing predators. Here we consider the morphogenetic process that shapes these structures and underlies their repeated emergence. We develop a mathematical model for spine morphogenesis based on the mechanical interaction between the secreting mantle edge and the calcified shell edge to which the mantle adheres during shell growth. It is demonstrated that a large diversity of spine structures can be accounted for through small variations in control parameters of this natural mechanical process. This physical mechanism suggests that convergent evolution of spines can be understood through a generic morphogenetic process, and provides unique perspectives in understanding the phenotypic evolution of this second largest phylum in the animal kingdom.

Mechanical basis of morphogenesis and convergent evolution of spiny seashells

KAUST Repository

Chirat, R.

2013-03-25

Convergent evolution is a phenomenon whereby similar traits evolved independently in not closely related species, and is often interpreted in functional terms. Spines in mollusk seashells are classically interpreted as having repeatedly evolved as a defense in response to shell-crushing predators. Here we consider the morphogenetic process that shapes these structures and underlies their repeated emergence. We develop a mathematical model for spine morphogenesis based on the mechanical interaction between the secreting mantle edge and the calcified shell edge to which the mantle adheres during shell growth. It is demonstrated that a large diversity of spine structures can be accounted for through small variations in control parameters of this natural mechanical process. This physical mechanism suggests that convergent evolution of spines can be understood through a generic morphogenetic process, and provides unique perspectives in understanding the phenotypic evolution of this second largest phylum in the animal kingdom.

Parallel vs. Convergent Evolution in Domestication and Diversification of Crops in the Americas

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Barbara Pickersgill

2018-05-01

Full Text Available Domestication involves changes in various traits of the phenotype in response to human selection. Diversification may accompany or follow domestication, and results in variants within the crop adapted to different uses by humans or different agronomic conditions. Similar domestication and diversification traits may be shared by closely related species (parallel evolution or by distantly related species (convergent evolution. Many of these traits are produced by complex genetic networks or long biosynthetic pathways that are extensively conserved even in distantly related species. Similar phenotypic changes in different species may be controlled by homologous genes (parallel evolution at the genetic level or non-homologous genes (convergent evolution at the genetic level. It has been suggested that parallel evolution may be more frequent among closely related species, or among diversification rather than domestication traits, or among traits produced by simple metabolic pathways. Crops domesticated in the Americas span a spectrum of genetic relatedness, have been domesticated for diverse purposes, and have responded to human selection by changes in many different traits, so provide examples of both parallel and convergent evolution at various levels. However, despite the current explosion in relevant information, data are still insufficient to provide quantitative or conclusive assessments of the relative roles of these two processes in domestication and diversification

Toward a Predictive Framework for Convergent Evolution: Integrating Natural History, Genetic Mechanisms, and Consequences for the Diversity of Life.

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Agrawal, Anurag A

2017-08-01

A charm of biology as a scientific discipline is the diversity of life. Although this diversity can make laws of biology challenging to discover, several repeated patterns and general principles govern evolutionary diversification. Convergent evolution, the independent evolution of similar phenotypes, has been at the heart of one approach to understand generality in the evolutionary process. Yet understanding when and why organismal traits and strategies repeatedly evolve has been a central challenge. These issues were the focus of the American Society of Naturalists Vice Presidential Symposium in 2016 and are the subject of this collection of articles. Although naturalists have long made inferences about convergent evolution and its importance, there has been confusion in the interpretation of the pattern of convergence. Does convergence primarily indicate adaptation or constraint? How often should convergence be expected? Are there general principles that would allow us to predict where and when and by what mechanisms convergent evolution should occur? What role does natural history play in advancing our understanding of general evolutionary principles? In this introductory article, I address these questions, review several generalizations about convergent evolution that have emerged over the past 15 years, and present a framework for advancing the study and interpretation of convergence. Perhaps the most important emerging conclusion is that the genetic mechanisms of convergent evolution are phylogenetically conserved; that is, more closely related species tend to share the same genetic basis of traits, even when independently evolved. Finally, I highlight how the articles in this special issue further develop concepts, methodologies, and case studies at the frontier of our understanding of the causes and consequences of convergent evolution.

Advances and Challenges in Convergent Communication Networks

DEFF Research Database (Denmark)

Toral-Cruz, Homero; Mihovska, Albena

2017-01-01

Welcome to this special issue of Wireless Personal Communications on Advances and Challenges in Convergent Communication Networks. The main purpose of this special issue is to present new progresses and challenges in convergent networks. Communication networks play an important role in our daily...... life because they allow communicating and sharing contents between heterogeneous nodes around the globe. The emergence of multiple network architectures and emerging technologies have resulted in new applications and services over a heterogeneous network. This heterogeneous network has undergone...... significant challenges in recent years, such as the evolution to a converged network with the capability to support multiple services, while maintaining a satisfactory level of QoE/QoS, security, efficiency and trust. The special issue on Advances and Challenges in Convergent Communication Networks...

Convergent evolution in mechanical design of lamnid sharks and tunas.

Science.gov (United States)

Donley, Jeanine M; Sepulveda, Chugey A; Konstantinidis, Peter; Gemballa, Sven; Shadwick, Robert E

2004-05-06

The evolution of 'thunniform' body shapes in several different groups of vertebrates, including whales, ichthyosaurs and several species of large pelagic fishes supports the view that physical and hydromechanical demands provided important selection pressures to optimize body design for locomotion during vertebrate evolution. Recognition of morphological similarities between lamnid sharks (the most well known being the great white and the mako) and tunas has led to a general expectation that they also have converged in their functional design; however, no quantitative data exist on the mechanical performance of the locomotor system in lamnid sharks. Here we examine the swimming kinematics, in vivo muscle dynamics and functional morphology of the force-transmission system in a lamnid shark, and show that the evolutionary convergence in body shape and mechanical design between the distantly related lamnids and tunas is much more than skin deep; it extends to the depths of the myotendinous architecture and the mechanical basis for propulsive movements. We demonstrate that not only have lamnids and tunas converged to a much greater extent than previously known, but they have also developed morphological and functional adaptations in their locomotor systems that are unlike virtually all other fishes.

The Evolution of Ecosystems for Converging Technologies – Drivers and Barriers of Technology Exploration and Exploitation

DEFF Research Database (Denmark)

Laufs, Daniel; Giones, Ferran; Schultz, Carsten

2018-01-01

Convergent technologies, like biotechnology, rely on the contribution of multiple scientific disciplines and are applied to distant needs and markets. As such, the development of technologies and related applications fields require the evolution of ecosystems that involve multidisciplinary......, previously unrelated, actors in collaborative exploration and exploitation processes. We know little on how these processes unfold, in particular in the early stages of the ecosystem development. Previous research suggests that human and social capital [1], patents and VC funding [2], or market orientation....... This helps us to generate an understanding of the pattern of technology convergence as well as of the drivers and barriers that affect the innovation process. In order to develop a holistic framework of the interplay between technology exploration and exploitation and the relevant ecosystem, we perform...

Analysis of convergence for control problems governed by evolution ...

African Journals Online (AJOL)

The convergence of a scheme to minimize a class of a system of continuous optimal control problems characterized by a system of evolution equations and a system of linear inequality and equality constraints with multiplier imbedding is considered. The result is applied to some problems and the scheme is found to exhibit ...

Nonlinear convergence active vibration absorber for single and multiple frequency vibration control

Science.gov (United States)

Wang, Xi; Yang, Bintang; Guo, Shufeng; Zhao, Wenqiang

2017-12-01

This paper presents a nonlinear convergence algorithm for active dynamic undamped vibration absorber (ADUVA). The damping of absorber is ignored in this algorithm to strengthen the vibration suppressing effect and simplify the algorithm at the same time. The simulation and experimental results indicate that this nonlinear convergence ADUVA can help significantly suppress vibration caused by excitation of both single and multiple frequency. The proposed nonlinear algorithm is composed of equivalent dynamic modeling equations and frequency estimator. Both the single and multiple frequency ADUVA are mathematically imitated by the same mechanical structure with a mass body and a voice coil motor (VCM). The nonlinear convergence estimator is applied to simultaneously satisfy the requirements of fast convergence rate and small steady state frequency error, which are incompatible for linear convergence estimator. The convergence of the nonlinear algorithm is mathematically proofed, and its non-divergent characteristic is theoretically guaranteed. The vibration suppressing experiments demonstrate that the nonlinear ADUVA can accelerate the convergence rate of vibration suppressing and achieve more decrement of oscillation attenuation than the linear ADUVA.

SINGLE VERSUS MULTIPLE TRIAL VECTORS IN CLASSICAL DIFFERENTIAL EVOLUTION FOR OPTIMIZING THE QUANTIZATION TABLE IN JPEG BASELINE ALGORITHM

Directory of Open Access Journals (Sweden)

B Vinoth Kumar

2017-07-01

Full Text Available Quantization Table is responsible for compression / quality trade-off in baseline Joint Photographic Experts Group (JPEG algorithm and therefore it is viewed as an optimization problem. In the literature, it has been found that Classical Differential Evolution (CDE is a promising algorithm to generate the optimal quantization table. However, the searching capability of CDE could be limited due to generation of single trial vector in an iteration which in turn reduces the convergence speed. This paper studies the performance of CDE by employing multiple trial vectors in a single iteration. An extensive performance analysis has been made between CDE and CDE with multiple trial vectors in terms of Optimization process, accuracy, convergence speed and reliability. The analysis report reveals that CDE with multiple trial vectors improves the convergence speed of CDE and the same is confirmed using a statistical hypothesis test (t-test.

From ground pools to treeholes: convergent evolution of habitat and phenotype in Aedes mosquitoes.

Science.gov (United States)

Soghigian, John; Andreadis, Theodore G; Livdahl, Todd P

2017-12-19

Invasive mosquito species are responsible for millions of vector-borne disease cases annually. The global invasive success of Aedes mosquitoes such as Aedes aegypti and Aedes albopictus has relied on the human transport of immature stages in container habitats. However, despite the importance of these mosquitoes and this ecological specialization to their widespread dispersal, evolution of habitat specialization in this group has remained largely unstudied. We use comparative methods to evaluate the evolution of habitat specialization and its potential influence on larval morphology, and evaluate whether container dwelling and invasiveness are monophyletic in Aedes. We show that habitat specialization has evolved repeatedly from ancestral ground pool usage to specialization in container habitats. Furthermore, we find that larval morphological scores are significantly associated with larval habitat when accounting for evolutionary relationships. We find that Ornstein-Uhleinbeck models with unique optima for each larval habitat type are preferred over several other models based predominantly on neutral processes, and that OU models can reliably simulate real morphological data. Our results demonstrate that multiple lineages of Aedes have convergently evolved a key trait associated with invasive success: the use of container habitats for immature stages. Moreover, our results demonstrate convergence in morphological characteristics as well, and suggest a role of adaptation to habitat specialization in driving phenotypic diversity in this mosquito lineage. Finally, our results highlight that the genus Aedes is not monophyletic.

Genetic architecture underlying convergent evolution of egg-laying behavior in a seed-feeding beetle.

Science.gov (United States)

Fox, Charles W; Wagner, James D; Cline, Sara; Thomas, Frances Ann; Messina, Frank J

2009-05-01

Independent populations subjected to similar environments often exhibit convergent evolution. An unresolved question is the frequency with which such convergence reflects parallel genetic mechanisms. We examined the convergent evolution of egg-laying behavior in the seed-feeding beetle Callosobruchus maculatus. Females avoid ovipositing on seeds bearing conspecific eggs, but the degree of host discrimination varies among geographic populations. In a previous experiment, replicate lines switched from a small host to a large one evolved reduced discrimination after 40 generations. We used line crosses to determine the genetic architecture underlying this rapid response. The most parsimonious genetic models included dominance and/or epistasis for all crosses. The genetic architecture underlying reduced discrimination in two lines was not significantly different from the architecture underlying differences between geographic populations, but the architecture underlying the divergence of a third line differed from all others. We conclude that convergence of this complex trait may in some cases involve parallel genetic mechanisms.

Ontogenetic convergence and evolution of foot morphology in European cave salamanders (Family: Plethodontidae

Directory of Open Access Journals (Sweden)

Nistri Annamaria

2010-07-01

Full Text Available Abstract Background A major goal in evolutionary biology is to understand the evolution of phenotypic diversity. Both natural and sexual selection play a large role in generating phenotypic adaptations, with biomechanical requirements and developmental mechanisms mediating patterns of phenotypic evolution. For many traits, the relative importance of selective and developmental components remains understudied. Results We investigated ontogenetic trajectories of foot morphology in the eight species of European plethodontid cave salamander to test the hypothesis that adult foot morphology was adapted for climbing. Using geometric morphometrics and other approaches, we found that developmental patterns in five species displayed little morphological change during growth (isometry, where the extensive interdigital webbing in adults was best explained as the retention of the juvenile morphological state. By contrast, three species exhibited significant allometry, with an increase in interdigital webbing during growth. Phylogenetic analyses revealed that multiple evolutionary transitions between isometry and allometry of foot webbing have occurred in this lineage. Allometric parameters of foot growth were most similar to those of a tropical species previously shown to be adapted for climbing. Finally, interspecific variation in adult foot morphology was significantly reduced as compared to variation among juveniles, indicating that ontogenetic convergence had resulted in a common adult foot morphology across species. Conclusions The results presented here provide evidence of a complex history of phenotypic evolution in this clade. The common adult phenotype exhibited among species reveals that selection plays an important part in generating patterns of foot diversity in the group. However, developmental trajectories arriving at this common morphology are distinct; with some species displaying developmental stasis (isometry, while others show an increase

Convergence in Multispecies Interactions

OpenAIRE

Bittleston, Leonora Sophia; Pierce, Naomi E.; Ellison, Aaron M.; Pringle, Anne

2016-01-01

The concepts of convergent evolution and community convergence highlight how selective pressures can shape unrelated organisms or communities in similar ways. We propose a related concept, convergent interactions, to describe the independent evolution of multispecies interactions with similar physiological or ecological functions. A focus on convergent interactions clarifies how natural selection repeatedly favors particular kinds of associations among species. Characterizing convergent inter...

Two developmentally temporal quantitative trait loci underlie convergent evolution of increased branchial bone length in sticklebacks

Science.gov (United States)

Erickson, Priscilla A.; Glazer, Andrew M.; Cleves, Phillip A.; Smith, Alyson S.; Miller, Craig T.

2014-01-01

In convergent evolution, similar phenotypes evolve repeatedly in independent populations, often reflecting adaptation to similar environments. Understanding whether convergent evolution proceeds via similar or different genetic and developmental mechanisms offers insight towards the repeatability and predictability of evolution. Oceanic populations of threespine stickleback fish, Gasterosteus aculeatus, have repeatedly colonized countless freshwater lakes and streams, where new diets lead to morphological adaptations related to feeding. Here, we show that heritable increases in branchial bone length have convergently evolved in two independently derived freshwater stickleback populations. In both populations, an increased bone growth rate in juveniles underlies the convergent adult phenotype, and one population also has a longer cartilage template. Using F2 crosses from these two freshwater populations, we show that two quantitative trait loci (QTL) control branchial bone length at distinct points in development. In both populations, a QTL on chromosome 21 controls bone length throughout juvenile development, and a QTL on chromosome 4 controls bone length only in adults. In addition to these similar developmental profiles, these QTL show similar chromosomal locations in both populations. Our results suggest that sticklebacks have convergently evolved longer branchial bones using similar genetic and developmental programmes in two independently derived populations. PMID:24966315

Convergent evolution of ribonuclease h in LTR retrotransposons and retroviruses.

Science.gov (United States)

Ustyantsev, Kirill; Novikova, Olga; Blinov, Alexander; Smyshlyaev, Georgy

2015-05-01

Ty3/Gypsy long terminals repeat (LTR) retrotransposons are structurally and phylogenetically close to retroviruses. Two notable structural differences between these groups of genetic elements are 1) the presence in retroviruses of an additional envelope gene, env, which mediates infection, and 2) a specific dual ribonuclease H (RNH) domain encoded by the retroviral pol gene. However, similar to retroviruses, many Ty3/Gypsy LTR retrotransposons harbor additional env-like genes, promoting concepts of the infective mode of these retrotransposons. Here, we provide a further line of evidence of similarity between retroviruses and some Ty3/Gypsy LTR retrotransposons. We identify that, together with their additional genes, plant Ty3/Gypsy LTR retrotransposons of the Tat group have a second RNH, as do retroviruses. Most importantly, we show that the resulting dual RNHs of Tat LTR retrotransposons and retroviruses emerged independently, providing strong evidence for their convergent evolution. The convergent resemblance of Tat LTR retrotransposons and retroviruses may indicate similar selection pressures acting on these diverse groups of elements and reveal potential evolutionary constraints on their structure. We speculate that dual RNH is required to accelerate retrotransposon evolution through increased rates of strand transfer events and subsequent recombination events. © The Author 2015. Published by Oxford University Press on behalf of the Society for Molecular Biology and Evolution.

Almost everywhere convergence over cubes of multiple trigonometric Fourier series

International Nuclear Information System (INIS)

Antonov, N Yu

2004-01-01

Under certain conditions on a function φ:[0,+∞)→[0,+∞) we prove a theorem asserting that the convergence almost everywhere of trigonometric Fourier series for all functions of class φ(L) [-π,π) implies the convergence over cubes of the multiple Fourier series and all its conjugates for an arbitrary function f element of φ(L)(log + L) d-1 ) [-π,π) d , d element of N. It follows from this and an earlier result of the author on the convergence almost everywhere of Fourier series of functions of one variable and class L(log + L)(log + log + log + L)) [-π,π) that if f element of L(log + L) d (log + log + log + L)) [-π,π) d , d element of N, then the Fourier series of f and all its conjugates converge over cubes almost everywhere

Cascades of convergent evolution: The corresponding evolutionary histories of euglenozoans and dinoflagellates

Czech Academy of Sciences Publication Activity Database

Lukeš, Julius; Leander, B. S.; Keeling, P. J.

2009-01-01

Roč. 106, č. 1 (2009), s. 9963-9970 ISSN 0027-8424 R&D Projects: GA ČR GA204/09/1667; GA MŠk LC07032; GA MŠk 2B06129 Institutional research plan: CEZ:AV0Z60220518 Keywords : comparative genomics * convergent evolution * dinoflagellates * Euglenozoa * mitochondria * molecular evolution * plastids * RNA editing * RNA editing Subject RIV: EB - Genetics ; Molecular Biology Impact factor: 9.432, year: 2009

Convergent evolution, habitat shifts and variable diversification rates in the ovenbird-woodcreeper family (Furnariidae).

Science.gov (United States)

Irestedt, Martin; Fjeldså, Jon; Dalén, Love; Ericson, Per G P

2009-11-21

The Neotropical ovenbird-woodcreeper family (Furnariidae) is an avian group characterized by exceptionally diverse ecomorphological adaptations. For instance, members of the family are known to construct nests of a remarkable variety. This offers a unique opportunity to examine whether changes in nest design, accompanied by expansions into new habitats, facilitates diversification. We present a multi-gene phylogeny and age estimates for the ovenbird-woodcreeper family and use these results to estimate the degree of convergent evolution in both phenotype and habitat utilisation. Furthermore, we discuss whether variation in species richness among ovenbird clades could be explained by differences in clade-specific diversification rates, and whether these rates differ among lineages with different nesting habits. In addition, the systematic positions of some enigmatic ovenbird taxa and the postulated monophyly of some species-rich genera are evaluated. The phylogenetic results reveal new examples of convergent evolution and show that ovenbirds have independently colonized open habitats at least six times. The calculated age estimates suggest that the ovenbird-woodcreeper family started to diverge at ca 33 Mya, and that the timing of habitat shifts into open environments may be correlated with the aridification of South America during the last 15 My. The results also show that observed large differences in species richness among clades can be explained by a substantial variation in net diversification rates. The synallaxines, which generally are adapted to dry habitats and build exposed vegetative nests, had the highest diversification rate of all major furnariid clades. Several key features may have played an important role for the radiation and evolution of convergent phenotypes in the ovenbird-woodcreeper family. Our results suggest that changes in nest building strategy and adaptation to novel habitats may have played an important role in a diversification that

Unexpected Convergent Evolution of Nasal Domes between Pleistocene Bovids and Cretaceous Hadrosaur Dinosaurs.

Science.gov (United States)

O'Brien, Haley D; Faith, J Tyler; Jenkins, Kirsten E; Peppe, Daniel J; Plummer, Thomas W; Jacobs, Zenobia L; Li, Bo; Joannes-Boyau, Renaud; Price, Gilbert; Feng, Yue-Xing; Tryon, Christian A

2016-02-22

The fossil record provides tangible, historical evidence for the mode and operation of evolution across deep time. Striking patterns of convergence are some of the strongest examples of these operations, whereby, over time, similar environmental and/or behavioral pressures precipitate similarity in form and function between disparately related taxa. Here we present fossil evidence for an unexpected convergence between gregarious plant-eating mammals and dinosaurs. Recent excavations of Late Pleistocene deposits on Rusinga Island, Kenya, have uncovered a catastrophic assemblage of the wildebeest-like bovid Rusingoryx atopocranion. Previously known from fragmentary material, these new specimens reveal large, hollow, osseous nasal crests: a craniofacial novelty for mammals that is remarkably comparable to the nasal crests of lambeosaurine hadrosaur dinosaurs. Using adult and juvenile material from this assemblage, as well as computed tomographic imaging, we investigate this convergence from morphological, developmental, functional, and paleoenvironmental perspectives. Our detailed analyses reveal broad parallels between R. atopocranion and basal Lambeosaurinae, suggesting that osseous nasal crests may require a highly specific combination of ontogeny, evolution, and environmental pressures in order to develop. Copyright © 2016 Elsevier Ltd. All rights reserved.

Convergence

Science.gov (United States)

Darcie, Thomas E.; Doverspike, Robert; Zirngibl, Martin; Korotky, Steven K.

2005-01-01

synchronous optical network) multiplexing hierarchy. From this common underlying theme follow many specific instantiations. Examples include the convergence at the physical, logical, and operational levels of voice and data, video and data, private-line and virtual private-line, fixed and mobile, and local and long-haul services. These trends have many consequences for consumers, vendors, and carriers. Faced with large volumes of low-margin data traffic mixed with traditional voice services, the need for capital conservation and operational efficiency drives carriers away from today's separate overlay networks for each service and towards "converged" platforms. For example, cable operators require transport of multiple services over both hybrid fiber coax (HFC) and DWDM transport technologies. Local carriers seek an economical architecture to deliver integrated services on optically enabled broadband-access networks. Services over wireless-access networks must coexist with those from wired networks. In each case, convergence of networks and services inspires an important set of questions and challenges, driven by the need for low cost, operational efficiency, service performance requirements, and optical transport technology options. This Feature Issue explores the various interpretations and implications of network convergence pertinent to optical networking. How does convergence affect the evolution of optical transport-layer and control approaches? Are the implied directions consistent with research vision for optical networks? Substantial challenges remain. Papers are solicited across the broad spectrum of interests. These include, but are not limited to: Architecture, design and performance of optical wide-area-network (WAN), metro, and access networks Integration strategies for multiservice transport platforms Access methods that bridge traditional and emerging services Network signaling and control methodologies All-optical packet routing and switching techniques

Convergence

Science.gov (United States)

Darcie, Thomas E.; Doverspike, Robert; Zirngibl, Martin; Korotky, Steven K.

2005-09-01

data, video and data, private-line and virtual private-line, fixed and mobile, and local and long-haul services. These trends have many consequences for consumers, vendors, and carriers. Faced with large volumes of low-margin data traffic mixed with traditional voice services, the need for capital conservation and operational efficiency drives carriers away from today's separate overlay networks for each service and towards "converged" platforms. For example, cable operators require transport of multiple services over both hybrid fiber coax (HFC) and DWDM transport technologies. Local carriers seek an economical architecture to deliver integrated services on optically enabled broadband-access networks. Services over wireless-access networks must coexist with those from wired networks. In each case, convergence of networks and services inspires an important set of questions and challenges, driven by the need for low cost, operational efficiency, service performance requirements, and optical transport technology options. This Feature Issue explores the various interpretations and implications of network convergence pertinent to optical networking. How does convergence affect the evolution of optical transport-layer and control approaches? Are the implied directions consistent with research vision for optical networks? Substantial challenges remain. Papers are solicited across the broad spectrum of interests. These include, but are not limited to: Architecture, design and performance of optical wide-area-network (WAN), metro, and access networks Integration strategies for multiservice transport platforms Access methods that bridge traditional and emerging services Network signaling and control methodologies All-optical packet routing and switching techniques To submit to this special issue, follow the normal procedure for submission to JON, indicating "Convergence feature" in the "Comments" field of the online submission form. For all other questions relating to this

Testing Convergent Evolution in Auditory Processing Genes between Echolocating Mammals and the Aye-Aye, a Percussive-Foraging Primate.

Science.gov (United States)

Bankoff, Richard J; Jerjos, Michael; Hohman, Baily; Lauterbur, M Elise; Kistler, Logan; Perry, George H

2017-07-01

Several taxonomically distinct mammalian groups-certain microbats and cetaceans (e.g., dolphins)-share both morphological adaptations related to echolocation behavior and strong signatures of convergent evolution at the amino acid level across seven genes related to auditory processing. Aye-ayes (Daubentonia madagascariensis) are nocturnal lemurs with a specialized auditory processing system. Aye-ayes tap rapidly along the surfaces of trees, listening to reverberations to identify the mines of wood-boring insect larvae; this behavior has been hypothesized to functionally mimic echolocation. Here we investigated whether there are signals of convergence in auditory processing genes between aye-ayes and known mammalian echolocators. We developed a computational pipeline (Basic Exon Assembly Tool) that produces consensus sequences for regions of interest from shotgun genomic sequencing data for nonmodel organisms without requiring de novo genome assembly. We reconstructed complete coding region sequences for the seven convergent echolocating bat-dolphin genes for aye-ayes and another lemur. We compared sequences from these two lemurs in a phylogenetic framework with those of bat and dolphin echolocators and appropriate nonecholocating outgroups. Our analysis reaffirms the existence of amino acid convergence at these loci among echolocating bats and dolphins; some methods also detected signals of convergence between echolocating bats and both mice and elephants. However, we observed no significant signal of amino acid convergence between aye-ayes and echolocating bats and dolphins, suggesting that aye-aye tap-foraging auditory adaptations represent distinct evolutionary innovations. These results are also consistent with a developing consensus that convergent behavioral ecology does not reliably predict convergent molecular evolution. © The Author 2017. Published by Oxford University Press on behalf of the Society for Molecular Biology and Evolution.

On convergence of differential evolution over a class of continuous functions with unique global optimum.

Science.gov (United States)

Ghosh, Sayan; Das, Swagatam; Vasilakos, Athanasios V; Suresh, Kaushik

2012-02-01

Differential evolution (DE) is arguably one of the most powerful stochastic real-parameter optimization algorithms of current interest. Since its inception in the mid 1990s, DE has been finding many successful applications in real-world optimization problems from diverse domains of science and engineering. This paper takes a first significant step toward the convergence analysis of a canonical DE (DE/rand/1/bin) algorithm. It first deduces a time-recursive relationship for the probability density function (PDF) of the trial solutions, taking into consideration the DE-type mutation, crossover, and selection mechanisms. Then, by applying the concepts of Lyapunov stability theorems, it shows that as time approaches infinity, the PDF of the trial solutions concentrates narrowly around the global optimum of the objective function, assuming the shape of a Dirac delta distribution. Asymptotic convergence behavior of the population PDF is established by constructing a Lyapunov functional based on the PDF and showing that it monotonically decreases with time. The analysis is applicable to a class of continuous and real-valued objective functions that possesses a unique global optimum (but may have multiple local optima). Theoretical results have been substantiated with relevant computer simulations.

Convergence diagnostics for Eigenvalue problems with linear regression model

International Nuclear Information System (INIS)

Shi, Bo; Petrovic, Bojan

2011-01-01

Although the Monte Carlo method has been extensively used for criticality/Eigenvalue problems, a reliable, robust, and efficient convergence diagnostics method is still desired. Most methods are based on integral parameters (multiplication factor, entropy) and either condense the local distribution information into a single value (e.g., entropy) or even disregard it. We propose to employ the detailed cycle-by-cycle local flux evolution obtained by using mesh tally mechanism to assess the source and flux convergence. By applying a linear regression model to each individual mesh in a mesh tally for convergence diagnostics, a global convergence criterion can be obtained. We exemplify this method on two problems and obtain promising diagnostics results. (author)

Comparative Analysis of Gene Expression for Convergent Evolution of Camera Eye Between Octopus and Human

Science.gov (United States)

Ogura, Atsushi; Ikeo, Kazuho; Gojobori, Takashi

2004-01-01

Although the camera eye of the octopus is very similar to that of humans, phylogenetic and embryological analyses have suggested that their camera eyes have been acquired independently. It has been known as a typical example of convergent evolution. To study the molecular basis of convergent evolution of camera eyes, we conducted a comparative analysis of gene expression in octopus and human camera eyes. We sequenced 16,432 ESTs of the octopus eye, leading to 1052 nonredundant genes that have matches in the protein database. Comparing these 1052 genes with 13,303 already-known ESTs of the human eye, 729 (69.3%) genes were commonly expressed between the human and octopus eyes. On the contrary, when we compared octopus eye ESTs with human connective tissue ESTs, the expression similarity was quite low. To trace the evolutionary changes that are potentially responsible for camera eye formation, we also compared octopus-eye ESTs with the completed genome sequences of other organisms. We found that 1019 out of the 1052 genes had already existed at the common ancestor of bilateria, and 875 genes were conserved between humans and octopuses. It suggests that a larger number of conserved genes and their similar gene expression may be responsible for the convergent evolution of the camera eye. PMID:15289475

Trait-specific processes of convergence and conservatism shape ecomorphological evolution in ground-dwelling squirrels.

Science.gov (United States)

McLean, Bryan S; Helgen, Kristofer M; Goodwin, H Thomas; Cook, Joseph A

2018-03-01

Our understanding of mechanisms operating over deep timescales to shape phenotypic diversity often hinges on linking variation in one or few trait(s) to specific evolutionary processes. When distinct processes are capable of similar phenotypic signatures, however, identifying these drivers is difficult. We explored ecomorphological evolution across a radiation of ground-dwelling squirrels whose history includes convergence and constraint, two processes that can yield similar signatures of standing phenotypic diversity. Using four ecologically relevant trait datasets (body size, cranial, mandibular, and molariform tooth shape), we compared and contrasted variation, covariation, and disparity patterns in a new phylogenetic framework. Strong correlations existed between body size and two skull traits (allometry) and among skull traits themselves (integration). Inferred evolutionary modes were also concordant across traits (Ornstein-Uhlenbeck with two adaptive regimes). However, despite these broad similarities, we found divergent dynamics on the macroevolutionary landscape, with phenotypic disparity being differentially shaped by convergence and conservatism. Such among-trait heterogeneity in process (but not always pattern) reiterates the mosaic nature of morphological evolution, and suggests ground squirrel evolution is poorly captured by single process descriptors. Our results also highlight how use of single traits can bias macroevolutionary inference, affirming the importance of broader trait-bases in understanding phenotypic evolutionary dynamics. © 2018 The Author(s). Evolution © 2018 The Society for the Study of Evolution.

Trophic convergence drives morphological convergence in marine tetrapods.

Science.gov (United States)

Kelley, Neil P; Motani, Ryosuke

2015-01-01

Marine tetrapod clades (e.g. seals, whales) independently adapted to marine life through the Mesozoic and Caenozoic, and provide iconic examples of convergent evolution. Apparent morphological convergence is often explained as the result of adaptation to similar ecological niches. However, quantitative tests of this hypothesis are uncommon. We use dietary data to classify the feeding ecology of extant marine tetrapods and identify patterns in skull and tooth morphology that discriminate trophic groups across clades. Mapping these patterns onto phylogeny reveals coordinated evolutionary shifts in diet and morphology in different marine tetrapod lineages. Similarities in morphology between species with similar diets-even across large phylogenetic distances-are consistent with previous hypotheses that shared functional constraints drive convergent evolution in marine tetrapods.

Multiplicity in Early Stellar Evolution

Science.gov (United States)

Reipurth, B.; Clarke, C. J.; Boss, A. P.; Goodwin, S. P.; Rodríguez, L. F.; Stassun, K. G.; Tokovinin, A.; Zinnecker, H.

Observations from optical to centimeter wavelengths have demonstrated that multiple systems of two or more bodies is the norm at all stellar evolutionary stages. Multiple systems are widely agreed to result from the collapse and fragmentation of cloud cores, despite the inhibiting influence of magnetic fields. Surveys of class 0 protostars with millimeter interferometers have revealed a very high multiplicity frequency of about 2/3, even though there are observational difficulties in resolving close protobinaries, thus supporting the possibility that all stars could be born in multiple systems. Near-infrared adaptive optics observations of class I protostars show a lower binary frequency relative to the class 0 phase, a declining trend that continues through the class II/III stages to the field population. This loss of companions is a natural consequence of dynamical interplay in small multiple systems, leading to ejection of members. We discuss observational consequences of this dynamical evolution, and its influence on circumstellar disks, and we review the evolution of circumbinary disks and their role in defining binary mass ratios. Special attention is paid to eclipsing PMS binaries, which allow for observational tests of evolutionary models of early stellar evolution. Many stars are born in clusters and small groups, and we discuss how interactions in dense stellar environments can significantly alter the distribution of binary separations through dissolution of wider binaries. The binaries and multiples we find in the field are the survivors of these internal and external destructive processes, and we provide a detailed overview of the multiplicity statistics of the field, which form a boundary condition for all models of binary evolution. Finally, we discuss various formation mechanisms for massive binaries, and the properties of massive trapezia.

Convergence in Multispecies Interactions.

Science.gov (United States)

Bittleston, Leonora S; Pierce, Naomi E; Ellison, Aaron M; Pringle, Anne

2016-04-01

The concepts of convergent evolution and community convergence highlight how selective pressures can shape unrelated organisms or communities in similar ways. We propose a related concept, convergent interactions, to describe the independent evolution of multispecies interactions with similar physiological or ecological functions. A focus on convergent interactions clarifies how natural selection repeatedly favors particular kinds of associations among species. Characterizing convergent interactions in a comparative context is likely to facilitate prediction of the ecological roles of organisms (including microbes) in multispecies interactions and selective pressures acting in poorly understood or newly discovered multispecies systems. We illustrate the concept of convergent interactions with examples: vertebrates and their gut bacteria; ectomycorrhizae; insect-fungal-bacterial interactions; pitcher-plant food webs; and ants and ant-plants. Copyright © 2016 Elsevier Ltd. All rights reserved.

Evolution of the Converged NGN Service Platforms Towards Future Networks

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Eugen Mikóczy

2011-03-01

Full Text Available This article presents a comparison of main characteristics of the Next Generation Networks (NGN and Future Generation Internet (FGI. The aim is to discuss and compare two approaches to Future Networks (FN and services: the evolution of NGN, and the revolutionary approach of a new FGI. We present both frameworks from the services point of view as they are delivered to the end-user, as well as from the architectural point of view. We compare selected properties of both approaches to explain commonalities and differences. Their challenges are similar: managing the quality of experience, mobility, security, scalability and providing openness to applications. Based on this comparison, we evaluate possible areas for future convergence in the approach of the two architectures to the Future Network concept. Our analysis shows that despite their different backgrounds, the internet’s FGI and telco’s NGN are not that different after all. The convergence of the two approaches therefore seems the only logical way forward.

Effect of preparation convergence on retention of multiple unit restorations - An in vitrostudy

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Dileep Nag Vinnakota

2015-01-01

Full Text Available Background and Aim: Convergence angle (CA is one of the major determinant factors in the retention of single as well as multiple units. Hence, the aim of the present study was to determine the effect of preparation convergence on the retention of multiple unit restorations. Materials and Methods: Nickel-chromium alloy single crowns as well as three, six and nine multiple unit fixed partial dentures (FPDs were casted for standardized milled dies that simulate canine, premolar and molar teeth machined with two different degrees of convergence, 12 (n = 55 and 20 (n = 55. The dies were threaded on rectangular metal platforms with the help of retainer shaft in the proper position to model either single or multiple preparations. The casted crowns and FPDs were cemented and retention tested by securing the units in an Instron universal testing machine. The tabulated values were analyzed statistically using Mann-Whitney test. Results: Single and multiple units with 12° CA needed greater force to dislodge compared to 20°, but this difference was not statistically significant for single units of premolar (P > 0.05. Irrespective of the angle, there was a simultaneous statistically significant increase in retention as the number of units increased in FPDs, except for the difference between 3 and 6 units in 20° group (P > 0.05. Conclusion: This study highlights the importance of emphasizing on CA, during canine and molar preparation for single units as well as preparation of canines for 6 units FPDs.

Evolution of Scale Worms

DEFF Research Database (Denmark)

Gonzalez, Brett Christopher

) caves, and the interstitium, recovering six monophyletic clades within Aphroditiformia: Acoetidae, Aphroditidae, Eulepethidae, Iphionidae, Polynoidae, and Sigalionidae (inclusive of the former ‘Pisionidae’ and ‘Pholoidae’), respectively. Tracing of morphological character evolution showed a high degree...... of adaptability and convergent evolution between relatively closely related scale worms. While some morphological and behavioral modifications in cave polynoids reflected troglomorphism, other modifications like eye loss were found to stem from a common ancestor inhabiting the deep sea, further corroborating...... the deep sea ancestry of scale worm cave fauna. In conclusion, while morphological characterization across Aphroditiformia appears deceptively easy due to the presence of elytra, convergent evolution during multiple early radiations across wide ranging habitats have confounded our ability to reconstruct...

Convergent evolution in aquatic tetrapods: insights from an exceptional fossil mosasaur.

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Johan Lindgren

Full Text Available Mosasaurs (family Mosasauridae are a diverse group of secondarily aquatic lizards that radiated into marine environments during the Late Cretaceous (98-65 million years ago. For the most part, they have been considered to be simple anguilliform swimmers--i.e., their propulsive force was generated by means of lateral undulations incorporating the greater part of the body--with unremarkable, dorsoventrally narrow tails and long, lizard-like bodies. Convergence with the specialized fusiform body shape and inferred carangiform locomotory style (in which only a portion of the posterior body participates in the thrust-producing flexure of ichthyosaurs and metriorhynchid crocodyliform reptiles, along with cetaceans, has so far only been recognized in Plotosaurus, the most highly derived member of the Mosasauridae. Here we report on an exceptionally complete specimen (LACM 128319 of the moderately derived genus Platecarpus that preserves soft tissues and anatomical details (e.g., large portions of integument, a partial body outline, putative skin color markings, a downturned tail, branching bronchial tubes, and probable visceral traces to an extent that has never been seen previously in any mosasaur. Our study demonstrates that a streamlined body plan and crescent-shaped caudal fin were already well established in Platecarpus, a taxon that preceded Plotosaurus by 20 million years. These new data expand our understanding of convergent evolution among marine reptiles, and provide insights into their evolution's tempo and mode.

Convergent evolution of marine mammals is associated with distinct substitutions in common genes

Science.gov (United States)

Zhou, Xuming; Seim, Inge; Gladyshev, Vadim N.

2015-01-01

Phenotypic convergence is thought to be driven by parallel substitutions coupled with natural selection at the sequence level. Multiple independent evolutionary transitions of mammals to an aquatic environment offer an opportunity to test this thesis. Here, whole genome alignment of coding sequences identified widespread parallel amino acid substitutions in marine mammals; however, the majority of these changes were not unique to these animals. Conversely, we report that candidate aquatic adaptation genes, identified by signatures of likelihood convergence and/or elevated ratio of nonsynonymous to synonymous nucleotide substitution rate, are characterized by very few parallel substitutions and exhibit distinct sequence changes in each group. Moreover, no significant positive correlation was found between likelihood convergence and positive selection in all three marine lineages. These results suggest that convergence in protein coding genes associated with aquatic lifestyle is mainly characterized by independent substitutions and relaxed negative selection. PMID:26549748

Convergent evolution and adaptation of Pseudomonas aeruginosa within patients with cystic fibrosis.

Science.gov (United States)

Marvig, Rasmus Lykke; Sommer, Lea Mette; Molin, Søren; Johansen, Helle Krogh

2015-01-01

Little is known about how within-host evolution compares between genotypically different strains of the same pathogenic species. We sequenced the whole genomes of 474 longitudinally collected clinical isolates of Pseudomonas aeruginosa sampled from 34 children and young individuals with cystic fibrosis. Our analysis of 36 P. aeruginosa lineages identified convergent molecular evolution in 52 genes. This list of genes suggests a role in host adaptation for remodeling of regulatory networks and central metabolism, acquisition of antibiotic resistance and loss of extracellular virulence factors. Furthermore, we find an ordered succession of mutations in key regulatory networks. Accordingly, mutations in downstream transcriptional regulators were contingent upon mutations in upstream regulators, suggesting that remodeling of regulatory networks might be important in adaptation. The characterization of genes involved in host adaptation may help in predicting bacterial evolution in patients with cystic fibrosis and in the design of future intervention strategies.

Convergence

DEFF Research Database (Denmark)

Madsen, Ole Brun; Nielsen, Jens Frederik Dalsgaard; Schiøler, Henrik

2002-01-01

Convergence trends between the WAN Internet area, characterized by best effort service provision, and the real time LAN domain, with requirements for guaranteed services, are identified and discussed. A bilateral evolution is identified, where typical bulk service applications from WAN, such as m......Convergence trends between the WAN Internet area, characterized by best effort service provision, and the real time LAN domain, with requirements for guaranteed services, are identified and discussed. A bilateral evolution is identified, where typical bulk service applications from WAN...... with the emergence of remote service provision, such as supervision and control of decentralized heating facilities and wind based electrical power production. The reliability issue is addressed from a structural viewpoint, where the concept of Structural QoS (SQoS) is defined to support reliability modelling...

Morphological convergence in ‘river dolphin’ skulls

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Charlotte E. Page

2017-11-01

Full Text Available Convergent evolution can provide insights into the predictability of, and constraints on, the evolution of biodiversity. One striking example of convergence is seen in the ‘river dolphins’. The four dolphin genera that make up the ‘river dolphins’ (Inia geoffrensis, Pontoporia blainvillei, Platanista gangetica and Lipotes vexillifer do not represent a single monophyletic group, despite being very similar in morphology. This has led many to using the ‘river dolphins’ as an example of convergent evolution. We investigate whether the skulls of the four ‘river dolphin’ genera are convergent when compared to other toothed dolphin taxa in addition to identifying convergent cranial and mandibular features. We use geometric morphometrics to uncover shape variation in the skulls of the ‘river dolphins’ and then apply a number of phylogenetic techniques to test for convergence. We find significant convergence in the skull morphology of the ‘river dolphins’. The four genera seem to have evolved similar skull shapes, leading to a convergent morphotype characterised by elongation of skull features. The cause of this morphological convergence remains unclear. However, the features we uncover as convergent, in particular elongation of the rostrum, support hypotheses of shared feeding mode or diet and thus provide the foundation for future work into convergence within the Odontoceti.

Convergent evolution and mimicry of protein linear motifs in host-pathogen interactions.

Science.gov (United States)

Chemes, Lucía Beatriz; de Prat-Gay, Gonzalo; Sánchez, Ignacio Enrique

2015-06-01

Pathogen linear motif mimics are highly evolvable elements that facilitate rewiring of host protein interaction networks. Host linear motifs and pathogen mimics differ in sequence, leading to thermodynamic and structural differences in the resulting protein-protein interactions. Moreover, the functional output of a mimic depends on the motif and domain repertoire of the pathogen protein. Regulatory evolution mediated by linear motifs can be understood by measuring evolutionary rates, quantifying positive and negative selection and performing phylogenetic reconstructions of linear motif natural history. Convergent evolution of linear motif mimics is widespread among unrelated proteins from viral, prokaryotic and eukaryotic pathogens and can also take place within individual protein phylogenies. Statistics, biochemistry and laboratory models of infection link pathogen linear motifs to phenotypic traits such as tropism, virulence and oncogenicity. In vitro evolution experiments and analysis of natural sequences suggest that changes in linear motif composition underlie pathogen adaptation to a changing environment. Copyright © 2015 Elsevier Ltd. All rights reserved.

Searching for convergent evolution in manganese superoxidase dismutase using hydrophobic cluster analysis

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Heng Xiang

2014-06-01

Full Text Available There are numerous examples of convergent evolution in nature. Major ecological adaptations such as flight, loss of limbs in vertebrates, pesticide resistance, adaptation to a parasitic way of life, etc., have all evolved more than once, as seen by their analogous functions in separate taxa. But what about protein evolution? Does the environment have a strong enough influence on intracellular processes that enzymes and other functional proteins play, to evolve similar functional roles separately in different organisms? Manganese Superoxide Dismutase (MnSOD is a manganesedependant metallo-enzyme which plays a crucial role in protecting cells from anti-oxidative stress by eliminating reactive (superoxide oxygen species. It is a ubiquitous housekeeping enzyme found in nearly all organisms. In this study we compare phylogenies based on MnSOD protein sequences to those based on scores from Hydrophobic Cluster Analysis (HCA. We calculated HCA similarity values for each pair of taxa to obtain a pair-wise distance matrix. A UPGMA tree based on the HCA distance matrix and a common tree based on the primary protein sequence for MnSOD was constructed. Differences between these two trees within animals, enterobacteriaceae, planctomycetes and cyanobacteria are presented and cited as possible examples of convergence. We note that several residue changes result in changes in hydrophobicity at positions which apparently are under the effect of positive selection.

A Convergent Differential Evolution Algorithm with Hidden Adaptation Selection for Engineering Optimization

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Zhongbo Hu

2014-01-01

Full Text Available Many improved differential Evolution (DE algorithms have emerged as a very competitive class of evolutionary computation more than a decade ago. However, few improved DE algorithms guarantee global convergence in theory. This paper developed a convergent DE algorithm in theory, which employs a self-adaptation scheme for the parameters and two operators, that is, uniform mutation and hidden adaptation selection (haS operators. The parameter self-adaptation and uniform mutation operator enhance the diversity of populations and guarantee ergodicity. The haS can automatically remove some inferior individuals in the process of the enhancing population diversity. The haS controls the proposed algorithm to break the loop of current generation with a small probability. The breaking probability is a hidden adaptation and proportional to the changes of the number of inferior individuals. The proposed algorithm is tested on ten engineering optimization problems taken from IEEE CEC2011.

Greater than the sum of its parts: single-nucleus sequencing identifies convergent evolution of independent EGFR mutants in GBM.

Science.gov (United States)

Gini, Beatrice; Mischel, Paul S

2014-08-01

Single-cell sequencing approaches are needed to characterize the genomic diversity of complex tumors, shedding light on their evolutionary paths and potentially suggesting more effective therapies. In this issue of Cancer Discovery, Francis and colleagues develop a novel integrative approach to identify distinct tumor subpopulations based on joint detection of clonal and subclonal events from bulk tumor and single-nucleus whole-genome sequencing, allowing them to infer a subclonal architecture. Surprisingly, the authors identify convergent evolution of multiple, mutually exclusive, independent EGFR gain-of-function variants in a single tumor. This study demonstrates the value of integrative single-cell genomics and highlights the biologic primacy of EGFR as an actionable target in glioblastoma. ©2014 American Association for Cancer Research.

Convergent evolution and adaptation of Pseudomonas aeruginosa within patients with cystic fibrosis

DEFF Research Database (Denmark)

Marvig, Rasmus Lykke; Madsen Sommer, Lea Mette; Molin, Søren

2015-01-01

fibrosis. Our analysis of 36 P. aeruginosa lineages identified convergent molecular evolution in 52 genes. This list of genes suggests a role in host adaptation for remodeling of regulatory networks and central metabolism, acquisition of antibiotic resistance and loss of extracellular virulence factors....... Furthermore, we find an ordered succession of mutations in key regulatory networks. Accordingly, mutations in downstream transcriptional regulators were contingent upon mutations in upstream regulators, suggesting that remodeling of regulatory networks might be important in adaptation. The characterization...

Adaptation and convergent evolution within the Jamesonia-Eriosorus complex in high-elevation biodiverse Andean hotspots.

Science.gov (United States)

Sánchez-Baracaldo, Patricia; Thomas, Gavin H

2014-01-01

The recent uplift of the tropical Andes (since the late Pliocene or early Pleistocene) provided extensive ecological opportunity for evolutionary radiations. We test for phylogenetic and morphological evidence of adaptive radiation and convergent evolution to novel habitats (exposed, high-altitude páramo habitats) in the Andean fern genera Jamesonia and Eriosorus. We construct time-calibrated phylogenies for the Jamesonia-Eriosorus clade. We then use recent phylogenetic comparative methods to test for evolutionary transitions among habitats, associations between habitat and leaf morphology, and ecologically driven variation in the rate of morphological evolution. Páramo species (Jamesonia) display morphological adaptations consistent with convergent evolution in response to the demands of a highly exposed environment but these adaptations are associated with microhabitat use rather than the páramo per se. Species that are associated with exposed microhabitats (including Jamesonia and Eriorsorus) are characterized by many but short pinnae per frond whereas species occupying sheltered microhabitats (primarily Eriosorus) have few but long pinnae per frond. Pinnae length declines more rapidly with altitude in sheltered species. Rates of speciation are significantly higher among páramo than non-páramo lineages supporting the hypothesis of adaptation and divergence in the unique Páramo biodiversity hotspot.

Cooperative target convergence using multiple agents

International Nuclear Information System (INIS)

Kwok, K.S.; Driessen, B.J.

1997-01-01

This work considers the problem of causing multiple (100''s) autonomous mobile robots to converge to a target and provides a follow-the-leader approach to the problem. Each robot has only a limited-range sensor for sending the target and also larger but also limited-range robot-to-robot communication capability. Because of the small amount of information available to the robots, a practical approach to improve convergence to the target is to have a robot follow the robot with the best quality of information. Specifically, each robot emits a signal that informs in-range robots what its status is. A robot has a status value of 0 if it is itself in range of the target. A robot has a status of 1 if it is not in range of the target but is in communication range of a robot that is in range of the target. A robot has a status of 2 if it is not in range of the target but is within range of another robot that has status 1, and so on. Of all the mobile robots that any given robot is in range of, it follows the one with the best status. The emergent behavior is the ant-like trails of robots following each other toward the target. If the robot is not in range of another robot that is either in range of the target or following another robot, the robot will assign-1 to its quality-of-information, and will execute an exhaustive search. The exhaustive search will continue until it encounters either the target or another robot with a nonnegative quality-of-information. The quality of information approach was extended to the case where each robot only has two-bit signals informing it of distance to in-range robots

Cooperative target convergence using multiple agents

Energy Technology Data Exchange (ETDEWEB)

Kwok, K.S.; Driessen, B.J.

1997-10-01

This work considers the problem of causing multiple (100`s) autonomous mobile robots to converge to a target and provides a follow-the-leader approach to the problem. Each robot has only a limited-range sensor for sending the target and also larger but also limited-range robot-to-robot communication capability. Because of the small amount of information available to the robots, a practical approach to improve convergence to the target is to have a robot follow the robot with the best quality of information. Specifically, each robot emits a signal that informs in-range robots what its status is. A robot has a status value of 0 if it is itself in range of the target. A robot has a status of 1 if it is not in range of the target but is in communication range of a robot that is in range of the target. A robot has a status of 2 if it is not in range of the target but is within range of another robot that has status 1, and so on. Of all the mobile robots that any given robot is in range of, it follows the one with the best status. The emergent behavior is the ant-like trails of robots following each other toward the target. If the robot is not in range of another robot that is either in range of the target or following another robot, the robot will assign-1 to its quality-of-information, and will execute an exhaustive search. The exhaustive search will continue until it encounters either the target or another robot with a nonnegative quality-of-information. The quality of information approach was extended to the case where each robot only has two-bit signals informing it of distance to in-range robots.

Convergent, Parallel and Correlated Evolution of Trophic Morphologies in the Subfamily Schizothoracinae from the Qinghai-Tibetan Plateau

Science.gov (United States)

Qi, Delin; Chao, Yan; Guo, Songchang; Zhao, Lanying; Li, Taiping; Wei, Fulei; Zhao, Xinquan

2012-01-01

Schizothoracine fishes distributed in the water system of the Qinghai-Tibetan plateau (QTP) and adjacent areas are characterized by being highly adaptive to the cold and hypoxic environment of the plateau, as well as by a high degree of diversity in trophic morphology due to resource polymorphisms. Although convergent and parallel evolution are prevalent in the organisms of the QTP, it remains unknown whether similar evolutionary patterns have occurred in the schizothoracine fishes. Here, we constructed for the first time a tentative molecular phylogeny of the schizothoracine fishes based on the complete sequences of the cytochrome b gene. We employed this molecular phylogenetic framework to examine the evolution of trophic morphologies. We used Pagel's maximum likelihood method to estimate the evolutionary associations of trophic morphologies and food resource use. Our results showed that the molecular and published morphological phylogenies of Schizothoracinae are partially incongruent with respect to some intergeneric relationships. The phylogenetic results revealed that four character states of five trophic morphologies and of food resource use evolved at least twice during the diversification of the subfamily. State transitions are the result of evolutionary patterns including either convergence or parallelism or both. Furthermore, our analyses indicate that some characters of trophic morphologies in the Schizothoracinae have undergone correlated evolution, which are somewhat correlated with different food resource uses. Collectively, our results reveal new examples of convergent and parallel evolution in the organisms of the QTP. The adaptation to different trophic niches through the modification of trophic morphologies and feeding behaviour as found in the schizothoracine fishes may account for the formation and maintenance of the high degree of diversity and radiations in fish communities endemic to QTP. PMID:22470515

Macrobothriotaenia ficta (Cestoda: Proteocephalidea), a parasite of sunbeam snake (Xenopeltis unicolor): example of convergent evolution

Czech Academy of Sciences Publication Activity Database

Scholz, Tomáš; de Chambrier, A.; Kuchta, Roman; Littlewood, D. T. J.; Waeschenbach, A.

2013-01-01

Roč. 3640, č. 3 (2013), s. 485-499 ISSN 1175-5326 R&D Projects: GA ČR GAP506/12/1632 Institutional support: RVO:60077344 Keywords : morphology * scolex * multilocus phylogenetic analysis * convergent evolution * redescription * Ophidia * Xenopeltidae * South-East Asia Subject RIV: EB - Genetics ; Molecular Biology Impact factor: 1.060, year: 2013

Convergent evolution in European and Rroma populations reveals pressure exerted by plague on Toll-like receptors

NARCIS (Netherlands)

Laayouni, H.; Oosting, M.; Luisi, P.; Ioana, M.; Alonso, S.; Ricano-Ponce, I.; Trynka, G.; Zhernakova, A.; Plantinga, T.S.; Cheng, S.C.; Meer, J.W. van der; Popp, R.; Sood, A.; Thelma, B.K.; Wijmenga, C.; Joosten, L.A.; Bertranpetit, J.; Netea, M.G.

2014-01-01

Recent historical periods in Europe have been characterized by severe epidemic events such as plague, smallpox, or influenza that shaped the immune system of modern populations. This study aims to identify signals of convergent evolution of the immune system, based on the peculiar demographic

Convergent evolution of RFX transcription factors and ciliary genes predated the origin of metazoans

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Chen Nansheng

2010-05-01

Full Text Available Abstract Background Intraflagellar transport (IFT genes, which are critical for the development and function of cilia and flagella in metazoans, are tightly regulated by the Regulatory Factor X (RFX transcription factors (TFs. However, how and when their evolutionary relationship was established remains unknown. Results We have identified evidence suggesting that RFX TFs and IFT genes evolved independently and their evolution converged before the first appearance of metazoans. Both ciliary genes and RFX TFs exist in all metazoans as well as some unicellular eukaryotes. However, while RFX TFs and IFT genes are found simultaneously in all sequenced metazoan genomes, RFX TFs do not co-exist with IFT genes in most pre-metazoans and thus do not regulate them in these organisms. For example, neither the budding yeast nor the fission yeast possesses cilia although both have well-defined RFX TFs. Conversely, most unicellular eukaryotes, including the green alga Chlamydomonas reinhardtii, have typical cilia and well conserved IFT genes but lack RFX TFs. Outside of metazoans, RFX TFs and IFT genes co-exist only in choanoflagellates including M. brevicollis, and only one fungus Allomyces macrogynus of the 51 sequenced fungus genomes. M. brevicollis has two putative RFX genes and a full complement of ciliary genes. Conclusions The evolution of RFX TFs and IFT genes were independent in pre-metazoans. We propose that their convergence in evolution, or the acquired transcriptional regulation of IFT genes by RFX TFs, played a pivotal role in the establishment of metazoan.

Convergent evolution towards high net carbon gain efficiency contributes to the shade tolerance of palms (Arecaceae)

NARCIS (Netherlands)

Ma, Ren Yi; Zhang, Jiao Lin; Cavaleri, Molly A.; Sterck, Frank; Strijk, J.S.; Cao, Kun Fang

2015-01-01

Most palm species occur in the shaded lower strata of tropical rain forests, but how their traits relate to shade adaptation is poorly understood. We hypothesized that palms are adapted to the shade of their native habitats by convergent evolution towards high net carbon gain efficiency (CGEn),

The Convergence Years

Science.gov (United States)

Kolodzy, Janet; Grant, August E.; DeMars, Tony R.; Wilkinson, Jeffrey S.

2014-01-01

The emergence of the Internet, social media, and digital technologies in the twenty-first century accelerated an evolution in journalism and communication that fit under the broad term of convergence. That evolution changed the relationship between news producers and consumers. It broke down the geographical boundaries in defining our communities,…

Convergent Evolution towards High Net Carbon Gain Efficiency Contributes to the Shade Tolerance of Palms (Arecaceae.

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Ren-Yi Ma

Full Text Available Most palm species occur in the shaded lower strata of tropical rain forests, but how their traits relate to shade adaptation is poorly understood. We hypothesized that palms are adapted to the shade of their native habitats by convergent evolution towards high net carbon gain efficiency (CGEn, which is given by the maximum photosynthetic rate to dark respiration rate ratio. Leaf mass per area, maximum photosynthetic rate, dark respiration and N and P concentrations were measured in 80 palm species grown in a common garden, and combined with data of 30 palm species growing in their native habitats. Compared to other species from the global leaf economics data, dicotyledonous broad-leaved trees in tropical rainforest or other monocots in the global leaf economics data, palms possessed consistently higher CGEn, achieved by lowered dark respiration and fairly high foliar P concentration. Combined phylogenetic analyses of evolutionary signal and trait evolution revealed convergent evolution towards high CGEn in palms. We conclude that high CGEn is an evolutionary strategy that enables palms to better adapt to shady environments than coexisting dicot tree species, and may convey advantages in competing with them in the tropical forest understory. These findings provide important insights for understanding the evolution and ecology of palms, and for understanding plant shade adaptations of lower rainforest strata. Moreover, given the dominant role of palms in tropical forests, these findings are important for modelling carbon and nutrient cycling in tropical forest ecosystems.

Convergent evolution of phenotypic integration and its alignment with morphological diversification in Caribbean Anolis ecomorphs.

Science.gov (United States)

Kolbe, Jason J; Revell, Liam J; Szekely, Brian; Brodie, Edmund D; Losos, Jonathan B

2011-12-01

The adaptive landscape and the G-matrix are keys concepts for understanding how quantitative characters evolve during adaptive radiation. In particular, whether the adaptive landscape can drive convergence of phenotypic integration (i.e., the pattern of phenotypic variation and covariation summarized in the P-matrix) is not well studied. We estimated and compared P for 19 morphological traits in eight species of Caribbean Anolis lizards, finding that similarity in P among species was not correlated with phylogenetic distance. However, greater similarity in P among ecologically similar Anolis species (i.e., the trunk-ground ecomorph) suggests the role of convergent natural selection. Despite this convergence and relatively deep phylogenetic divergence, a large portion of eigenstructure of P is retained among our eight focal species. We also analyzed P as an approximation of G to test for correspondence with the pattern of phenotypic divergence in 21 Caribbean Anolis species. These patterns of covariation were coincident, suggesting that either genetic constraint has influenced the pattern of among-species divergence or, alternatively, that the adaptive landscape has influenced both G and the pattern of phenotypic divergence among species. We provide evidence for convergent evolution of phenotypic integration for one class of Anolis ecomorph, revealing yet another important dimension of evolutionary convergence in this group. No Claim to original U.S. government works.

Convergent evolution: floral guides, stingless bee nest entrances, and insectivorous pitchers

Science.gov (United States)

Biesmeijer, Jacobus C.; Giurfa, Martin; Koedam, Dirk; Potts, Simon G.; Joel, Daniel M.; Dafni, Amots

2005-09-01

Several recent hypotheses, including sensory drive and sensory exploitation, suggest that receiver biases may drive selection of biological signals in the context of sexual selection. Here we suggest that a similar mechanism may have led to convergence of patterns in flowers, stingless bee nest entrances, and pitchers of insectivorous plants. A survey of these non-related visual stimuli shows that they share features such as stripes, dark centre, and peripheral dots. Next, we experimentally show that in stingless bees the close-up approach to a flower is guided by dark centre preference. Moreover, in the approach towards their nest entrance, they have a spontaneous preference for entrance patterns containing a dark centre and disrupted ornamentation. Together with existing empirical evidence on the honeybee's and other insects’ orientation to flowers, this suggests that the signal receivers of the natural patterns we examined, mainly Hymenoptera, have spontaneous preferences for radiating stripes, dark centres, and peripheral dots. These receiver biases may have evolved in other behavioural contexts in the ancestors of Hymenoptera, but our findings suggest that they have triggered the convergent evolution of visual stimuli in floral guides, stingless bee nest entrances, and insectivorous pitchers.

Industrial Evolution Through Complementary Convergence

DEFF Research Database (Denmark)

Frøslev Christensen, Jens

2011-01-01

The article addresses the dynamics through which product markets become derailed from early product life cycle (PLC)-tracks and engaged in complementary convergence with other product markets or industries. We compare and contrast the theories that can explain, respectively, the PLC...

Lacunary ideal convergence of multiple sequences

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Bipan Hazarika

2016-01-01

Full Text Available An ideal I is a family of subsets of N×N which is closed under taking finite unions and subsets of its elements. In this article, the concept of lacunary ideal convergence of double sequences has been introduced. Also the relation between lacunary ideal convergent and lacunary Cauchy double sequences has been established. Furthermore, the notions of lacunary ideal limit point and lacunary ideal cluster points have been introduced and find the relation between these two notions. Finally, we have studied the properties such as solidity, monotonic.

Cut from the same cloth: The convergent evolution of dwarf morphotypes of the Carex flava group (Cyperaceae) in Circum-Mediterranean mountains

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Benítez-Benítez, Carmen; Fernández-Mazuecos, Mario; Martín-Bravo, Santiago

2017-01-01

Plants growing in high-mountain environments may share common morphological features through convergent evolution resulting from an adaptative response to similar ecological conditions. The Carex flava species complex (sect. Ceratocystis, Cyperaceae) includes four dwarf morphotypes from Circum-Mediterranean mountains whose taxonomic status has remained obscure due to their apparent morphological resemblance. In this study we investigate whether these dwarf mountain morphotypes result from convergent evolution or common ancestry, and whether there are ecological differences promoting differentiation between the dwarf morphotypes and their taxonomically related large, well-developed counterparts. We used phylogenetic analyses of nrDNA (ITS) and ptDNA (rps16 and 5’trnK) sequences, ancestral state reconstruction, multivariate analyses of macro- and micromorphological data, and species distribution modeling. Dwarf morphotype populations were found to belong to three different genetic lineages, and several morphotype shifts from well-developed to dwarf were suggested by ancestral state reconstructions. Distribution modeling supported differences in climatic niche at regional scale between the large forms, mainly from lowland, and the dwarf mountain morphotypes. Our results suggest that dwarf mountain morphotypes within this sedge group are small forms of different lineages that have recurrently adapted to mountain habitats through convergent evolution. PMID:29281689

EMPIRICAL WEIGHTED MODELLING ON INTER-COUNTY INEQUALITIES EVOLUTION AND TO TEST ECONOMICAL CONVERGENCE IN ROMANIA

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Natalia\tMOROIANU‐DUMITRESCU

2015-06-01

Full Text Available During the last decades, the regional convergence process in Europe has attracted a considerable interest as a highly significant issue, especially after EU enlargement with the New Member States from Central and Eastern Europe. The most usual empirical approaches are using the β- and σ-convergence, originally developed by a series of neo-classical models. Up-to-date, the EU integration process was proven to be accompanied by an increase of the regional inequalities. In order to determine the existence of a similar increase of the inequalities between the administrative counties (NUTS3 included in the NUTS2 and NUTS1 regions of Romania, this paper provides an empirical modelling of economic convergence allowing to evaluate the level and evolution of the inter-regional inequalities over more than a decade period lasting from 1995 up to 2011. The paper presents the results of a large cross-sectional study of σ-convergence and weighted coefficient of variation, using GDP and population data obtained from the National Institute of Statistics of Romania. Both graphical representation including non-linear regression and the associated tables summarizing numerical values of the main statistical tests are demonstrating the impact of pre- accession policy on the economic development of all Romanian NUTS types. The clearly emphasised convergence in the middle time subinterval can be correlated with the pre-accession drastic changes on economic, political and social level, and with the opening of the Schengen borders for Romanian labor force in 2002.

Strong convergence of an extragradient-type algorithm for the multiple-sets split equality problem.

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Zhao, Ying; Shi, Luoyi

2017-01-01

This paper introduces a new extragradient-type method to solve the multiple-sets split equality problem (MSSEP). Under some suitable conditions, the strong convergence of an algorithm can be verified in the infinite-dimensional Hilbert spaces. Moreover, several numerical results are given to show the effectiveness of our algorithm.

Convergent evolution and divergent selection: lizards at the White Sands ecotone.

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Rosenblum, Erica Bree

2006-01-01

Ecological transition zones, where organismal phenotypes result from a delicate balance between selection and migration, highlight the interplay of local adaptation and gene flow. Here, I study the response of an entire species assemblage to natural selection across a common ecotone. Three lizard species, distributed along a dramatic environmental gradient in substrate color, display convergent adaptation of blanched coloration on the gypsum dunes of White Sands National Monument. I investigate the role of gene flow in modulating phenotypic response to selection by quantifying color variation and genetic variation across the ecotone. I find species differences in degree of background matching and in genetic connectivity of populations across the ecotone. Differences among species in phenotypic response to selection scale precisely to levels of genetic isolation. Species with higher levels of gene flow across the ecotone exhibit less dramatic responses to selection. Results also reveal a strong signal of ecologically mediated divergence for White Sands lizards. For all species, phenotypic variation is better explained by habitat similarity than genetic similarity. Convergent evolution of blanched coloration at White Sands clearly reflects the action of strong divergent selection; however, adaptive response appears to be modulated by gene flow and demographic history and can be predicted by divergence-with-gene-flow models.

Integrated model of multiple kernel learning and differential evolution for EUR/USD trading.

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Deng, Shangkun; Sakurai, Akito

2014-01-01

Currency trading is an important area for individual investors, government policy decisions, and organization investments. In this study, we propose a hybrid approach referred to as MKL-DE, which combines multiple kernel learning (MKL) with differential evolution (DE) for trading a currency pair. MKL is used to learn a model that predicts changes in the target currency pair, whereas DE is used to generate the buy and sell signals for the target currency pair based on the relative strength index (RSI), while it is also combined with MKL as a trading signal. The new hybrid implementation is applied to EUR/USD trading, which is the most traded foreign exchange (FX) currency pair. MKL is essential for utilizing information from multiple information sources and DE is essential for formulating a trading rule based on a mixture of discrete structures and continuous parameters. Initially, the prediction model optimized by MKL predicts the returns based on a technical indicator called the moving average convergence and divergence. Next, a combined trading signal is optimized by DE using the inputs from the prediction model and technical indicator RSI obtained from multiple timeframes. The experimental results showed that trading using the prediction learned by MKL yielded consistent profits.

Integrated Model of Multiple Kernel Learning and Differential Evolution for EUR/USD Trading

Directory of Open Access Journals (Sweden)

Shangkun Deng

2014-01-01

Full Text Available Currency trading is an important area for individual investors, government policy decisions, and organization investments. In this study, we propose a hybrid approach referred to as MKL-DE, which combines multiple kernel learning (MKL with differential evolution (DE for trading a currency pair. MKL is used to learn a model that predicts changes in the target currency pair, whereas DE is used to generate the buy and sell signals for the target currency pair based on the relative strength index (RSI, while it is also combined with MKL as a trading signal. The new hybrid implementation is applied to EUR/USD trading, which is the most traded foreign exchange (FX currency pair. MKL is essential for utilizing information from multiple information sources and DE is essential for formulating a trading rule based on a mixture of discrete structures and continuous parameters. Initially, the prediction model optimized by MKL predicts the returns based on a technical indicator called the moving average convergence and divergence. Next, a combined trading signal is optimized by DE using the inputs from the prediction model and technical indicator RSI obtained from multiple timeframes. The experimental results showed that trading using the prediction learned by MKL yielded consistent profits.

Plasticity and Convergence in the Evolution of Short-Necked Plesiosaurs.

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Fischer, Valentin; Benson, Roger B J; Zverkov, Nikolay G; Soul, Laura C; Arkhangelsky, Maxim S; Lambert, Olivier; Stenshin, Ilya M; Uspensky, Gleb N; Druckenmiller, Patrick S

2017-06-05

Plesiosaurs were the longest-surviving group of secondarily marine tetrapods, comparable in diversity to today's cetaceans. During their long evolutionary history, which spanned the Jurassic and the Cretaceous (201 to 66 Ma), plesiosaurs repeatedly evolved long- and short-necked body plans [1, 2]. Despite this postcranial plasticity, short-necked plesiosaur clades have traditionally been regarded as being highly constrained to persistent and clearly distinct ecological niches: advanced members of Pliosauridae (ranging from the Middle Jurassic to the early Late Cretaceous) have been characterized as apex predators [2-5], whereas members of the distantly related clade Polycotylidae (middle to Late Cretaceous) were thought to have been fast-swimming piscivores [1, 5-7]. We report a new, highly unusual pliosaurid from the Early Cretaceous of Russia that shows close convergence with the cranial structure of polycotylids: Luskhan itilensis gen. et sp. nov. Using novel cladistic and ecomorphological data, we show that pliosaurids iteratively evolved polycotylid-like cranial morphologies from the Early Jurassic until the Early Cretaceous. This underscores the ecological diversity of derived pliosaurids and reveals a more complex evolutionary history than their iconic representation as gigantic apex predators of Mesozoic marine ecosystems suggests. Collectively, these data demonstrate an even higher degree of morphological plasticity and convergence in the evolution of plesiosaurs than previously thought and suggest the existence of an optimal ecomorphology for short-necked piscivorous plesiosaurs through time and across phylogeny. Copyright © 2017 Elsevier Ltd. All rights reserved.

Convergent evolution of modularity in metabolic networks through different community structures

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Zhou Wanding

2012-09-01

Full Text Available Abstract Background It has been reported that the modularity of metabolic networks of bacteria is closely related to the variability of their living habitats. However, given the dependency of the modularity score on the community structure, it remains unknown whether organisms achieve certain modularity via similar or different community structures. Results In this work, we studied the relationship between similarities in modularity scores and similarities in community structures of the metabolic networks of 1021 species. Both similarities are then compared against the genetic distances. We revisited the association between modularity and variability of the microbial living environments and extended the analysis to other aspects of their life style such as temperature and oxygen requirements. We also tested both topological and biological intuition of the community structures identified and investigated the extent of their conservation with respect to the taxomony. Conclusions We find that similar modularities are realized by different community structures. We find that such convergent evolution of modularity is closely associated with the number of (distinct enzymes in the organism’s metabolome, a consequence of different life styles of the species. We find that the order of modularity is the same as the order of the number of the enzymes under the classification based on the temperature preference but not on the oxygen requirement. Besides, inspection of modularity-based communities reveals that these communities are graph-theoretically meaningful yet not reflective of specific biological functions. From an evolutionary perspective, we find that the community structures are conserved only at the level of kingdoms. Our results call for more investigation into the interplay between evolution and modularity: how evolution shapes modularity, and how modularity affects evolution (mainly in terms of fitness and evolvability. Further, our results

Convergent evolution of modularity in metabolic networks through different community structures.

Science.gov (United States)

Zhou, Wanding; Nakhleh, Luay

2012-09-14

It has been reported that the modularity of metabolic networks of bacteria is closely related to the variability of their living habitats. However, given the dependency of the modularity score on the community structure, it remains unknown whether organisms achieve certain modularity via similar or different community structures. In this work, we studied the relationship between similarities in modularity scores and similarities in community structures of the metabolic networks of 1021 species. Both similarities are then compared against the genetic distances. We revisited the association between modularity and variability of the microbial living environments and extended the analysis to other aspects of their life style such as temperature and oxygen requirements. We also tested both topological and biological intuition of the community structures identified and investigated the extent of their conservation with respect to the taxonomy. We find that similar modularities are realized by different community structures. We find that such convergent evolution of modularity is closely associated with the number of (distinct) enzymes in the organism's metabolome, a consequence of different life styles of the species. We find that the order of modularity is the same as the order of the number of the enzymes under the classification based on the temperature preference but not on the oxygen requirement. Besides, inspection of modularity-based communities reveals that these communities are graph-theoretically meaningful yet not reflective of specific biological functions. From an evolutionary perspective, we find that the community structures are conserved only at the level of kingdoms. Our results call for more investigation into the interplay between evolution and modularity: how evolution shapes modularity, and how modularity affects evolution (mainly in terms of fitness and evolvability). Further, our results call for exploring new measures of modularity and network

Evidence for convergent evolution of SINE-directed Staufen-mediated mRNA decay.

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Lucas, Bronwyn A; Lavi, Eitan; Shiue, Lily; Cho, Hana; Katzman, Sol; Miyoshi, Keita; Siomi, Mikiko C; Carmel, Liran; Ares, Manuel; Maquat, Lynne E

2018-01-30

Primate-specific Alu short interspersed elements (SINEs) as well as rodent-specific B and ID (B/ID) SINEs can promote Staufen-mediated decay (SMD) when present in mRNA 3'-untranslated regions (3'-UTRs). The transposable nature of SINEs, their presence in long noncoding RNAs, their interactions with Staufen, and their rapid divergence in different evolutionary lineages suggest they could have generated substantial modification of posttranscriptional gene-control networks during mammalian evolution. Some of the variation in SMD regulation produced by SINE insertion might have had a similar regulatory effect in separate mammalian lineages, leading to parallel evolution of the Staufen network by independent expansion of lineage-specific SINEs. To explore this possibility, we searched for orthologous gene pairs, each carrying a species-specific 3'-UTR SINE and each regulated by SMD, by measuring changes in mRNA abundance after individual depletion of two SMD factors, Staufen1 (STAU1) and UPF1, in both human and mouse myoblasts. We identified and confirmed orthologous gene pairs with 3'-UTR SINEs that independently function in SMD control of myoblast metabolism. Expanding to other species, we demonstrated that SINE-directed SMD likely emerged in both primate and rodent lineages >20-25 million years ago. Our work reveals a mechanism for the convergent evolution of posttranscriptional gene regulatory networks in mammals by species-specific SINE transposition and SMD.

Spatial evolution of Zagros collision zone in Kurdistan, NW Iran: constraints on Arabia-Eurasia oblique convergence

Science.gov (United States)

Sadeghi, Shahriar; Yassaghi, Ali

2016-04-01

Stratigraphy, detailed structural mapping and a crustal-scale cross section across the NW Zagros collision zone provide constraints on the spatial evolution of oblique convergence of the Arabian and Eurasian plates since the Late Cretaceous. The Zagros collision zone in NW Iran consists of the internal Sanandaj-Sirjan, Gaveh Rud and Ophiolite zones and the external Bisotoun, Radiolarite and High Zagros zones. The Main Zagros Thrust is the major structure of the Zagros suture zone. Two stages of oblique deformation are recognized in the external part of the NW Zagros in Iran. In the early stage, coexisting dextral strike-slip and reverse dominated domains in the Radiolarite zone developed in response to deformation partitioning due to oblique convergence. Dextral-reverse faults in the Bisotoun zone are also compatible with oblique convergence. In the late stage, deformation partitioning occurred during southeastward propagation of the Zagros orogeny towards its foreland resulting in synchronous development of orogen-parallel strike-slip and thrust faults. It is proposed that the first stage was related to Late Cretaceous oblique obduction, while the second stage resulted from Cenozoic collision. The Cenozoic orogen-parallel strike-slip component of Zagros oblique convergence is not confined to the Zagros suture zone (Main Recent Fault) but also occurred in the external part (Marekhil-Ravansar fault system). Thus, it is proposed that oblique convergence of Arabian and Eurasian plates in Zagros collision zone initiated with oblique obduction in the Late Cretaceous followed by oblique collision in the late Tertiary, consistent with global plate reconstructions.

Diversity, structure and convergent evolution of the global sponge microbiome

Science.gov (United States)

Thomas, Torsten; Moitinho-Silva, Lucas; Lurgi, Miguel; Björk, Johannes R.; Easson, Cole; Astudillo-García, Carmen; Olson, Julie B.; Erwin, Patrick M.; López-Legentil, Susanna; Luter, Heidi; Chaves-Fonnegra, Andia; Costa, Rodrigo; Schupp, Peter J.; Steindler, Laura; Erpenbeck, Dirk; Gilbert, Jack; Knight, Rob; Ackermann, Gail; Victor Lopez, Jose; Taylor, Michael W.; Thacker, Robert W.; Montoya, Jose M.; Hentschel, Ute; Webster, Nicole S.

2016-01-01

Sponges (phylum Porifera) are early-diverging metazoa renowned for establishing complex microbial symbioses. Here we present a global Porifera microbiome survey, set out to establish the ecological and evolutionary drivers of these host–microbe interactions. We show that sponges are a reservoir of exceptional microbial diversity and major contributors to the total microbial diversity of the world's oceans. Little commonality in species composition or structure is evident across the phylum, although symbiont communities are characterized by specialists and generalists rather than opportunists. Core sponge microbiomes are stable and characterized by generalist symbionts exhibiting amensal and/or commensal interactions. Symbionts that are phylogenetically unique to sponges do not disproportionally contribute to the core microbiome, and host phylogeny impacts complexity rather than composition of the symbiont community. Our findings support a model of independent assembly and evolution in symbiont communities across the entire host phylum, with convergent forces resulting in analogous community organization and interactions. PMID:27306690

The Continental Margin of East Asia: a collage of multiple plates formed by convergence and extension from multiple directions

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Mao, J.; Wang, T.; Ludington, S.; Qiu, Z.; Li, Z.

2017-12-01

East Asia is one of the most complex regions in the world. Its margin was divided into 4 parts: Northeast Asia, North China, South China and Southeast Asia. During the Phanerozoic, continental plates of East Asia have interacted successively with a) the Paleo Tethyan Ocean, b) the Tethyan and Paleo Pacific Oceans and c) the Pacific and Indian. In the Early Mesozoic, the Indosinian orogeny is characterized by the convergence and extension within multiple continental plates, whereas the Late Mesozoic Yanshanian orogeny is characterized by both convergence and compression due to oceanic subduction and by widespread extension. We propose this combination as "East Asia Continental Margin type." Except in Northeast Asia, where Jurassic and Cretaeous accretionary complexes are common, most magmatic rocks are the result of reworking of ancient margins of small continental plates; and oceanic island arc basalts and continental margin arc andesites are largely absent. Because South China is adjacent to the western margin of the Pacific Plate, some effects of its westward subduction must be unavoidable, but juvenile arc-related crust has not been identified. The East Asian Continental Margin is characterized by magmatic rocks that are the result of post-convergent tectonics, which differs markedly from the active continental margins of both South and North America. In summary, the chief characteristics of the East Asian Continental Margin are: 1) In Mesozoic, the periphery of multiple blocks experienced magmatism caused by lithospheric delamination and thinning in response to extension punctuated by shorter periods of convergence. 2) The main mechanism of magma generation was the partial melting of crustal rocks, due to underplating by upwelling mafic magma associated with the collapse of orogenic belts and both extension and compression between small continental blocks. 3) During orogeny, mostly high Sr/Y arc-related granitoids formed, whereas during post-orogenic times, A

SP Transcription Factor Paralogs and DNA-Binding Sites Coevolve and Adaptively Converge in Mammals and Birds

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Yokoyama, Ken Daigoro; Pollock, David D.

2012-01-01

Functional modification of regulatory proteins can affect hundreds of genes throughout the genome, and is therefore thought to be almost universally deleterious. This belief, however, has recently been challenged. A potential example comes from transcription factor SP1, for which statistical evidence indicates that motif preferences were altered in eutherian mammals. Here, we set out to discover possible structural and theoretical explanations, evaluate the role of selection in SP1 evolution, and discover effects on coregulatory proteins. We show that SP1 motif preferences were convergently altered in birds as well as mammals, inducing coevolutionary changes in over 800 regulatory regions. Structural and phylogenic evidence implicates a single causative amino acid replacement at the same SP1 position along both lineages. Furthermore, paralogs SP3 and SP4, which coregulate SP1 target genes through competitive binding to the same sites, have accumulated convergent replacements at the homologous position multiple times during eutherian and bird evolution, presumably to preserve competitive binding. To determine plausibility, we developed and implemented a simple model of transcription factor and binding site coevolution. This model predicts that, in contrast to prevailing beliefs, even small selective benefits per locus can drive concurrent fixation of transcription factor and binding site mutants under a broad range of conditions. Novel binding sites tend to arise de novo, rather than by mutation from ancestral sites, a prediction substantiated by SP1-binding site alignments. Thus, multiple lines of evidence indicate that selection has driven convergent evolution of transcription factors along with their binding sites and coregulatory proteins. PMID:23019068

Population genomic scans suggest novel genes underlie convergent flowering time evolution in the introduced range of Arabidopsis thaliana.

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Gould, Billie A; Stinchcombe, John R

2017-01-01

A long-standing question in evolutionary biology is whether the evolution of convergent phenotypes results from selection on the same heritable genetic components. Using whole-genome sequencing and genome scans, we tested whether the evolution of parallel longitudinal flowering time clines in the native and introduced ranges of Arabidopsis thaliana has a similar genetic basis. We found that common variants of large effect on flowering time in the native range do not appear to have been under recent strong selection in the introduced range. We identified a set of 38 new candidate genes that are putatively linked to the evolution of flowering time. A high degree of conditional neutrality of flowering time variants between the native and introduced range may preclude parallel evolution at the level of genes. Overall, neither gene pleiotropy nor available standing genetic variation appears to have restricted the evolution of flowering time to high-frequency variants from the native range or to known flowering time pathway genes. © 2016 John Wiley & Sons Ltd.

Convergent evolution of Hawaiian and Australo-Pacific honeyeaters from distant songbird ancestors.

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Fleischer, Robert C; James, Helen F; Olson, Storrs L

2008-12-23

The Hawaiian "honeyeaters," five endemic species of recently extinct, nectar-feeding songbirds in the genera Moho and Chaetoptila, looked and acted like Australasian honeyeaters (Meliphagidae), and no taxonomist since their discovery on James Cook's third voyage has classified them as anything else. We obtained DNA sequences from museum specimens of Moho and Chaetoptila collected in Hawaii 115-158 years ago. Phylogenetic analysis of these sequences supports monophyly of the two Hawaiian genera but, surprisingly, reveals that neither taxon is a meliphagid honeyeater, nor even in the same part of the songbird radiation as meliphagids. Instead, the Hawaiian species are divergent members of a passeridan group that includes deceptively dissimilar families of songbirds (Holarctic waxwings, neotropical silky flycatchers, and palm chats). Here we designate them as a new family, the Mohoidae. A nuclear-DNA rate calibration suggests that mohoids diverged from their closest living ancestor 14-17 mya, coincident with the estimated earliest arrival in Hawaii of a bird-pollinated plant lineage. Convergent evolution, the evolution of similar traits in distantly related taxa because of common selective pressures, is illustrated well by nectar-feeding birds, but the morphological, behavioral, and ecological similarity of the mohoids to the Australasian honeyeaters makes them a particularly striking example of the phenomenon.

Convergent Evolution of Slick Coat in Cattle through Truncation Mutations in the Prolactin Receptor

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Laercio R. Porto-Neto

2018-02-01

Full Text Available Evolutionary adaptations are occasionally convergent solutions to the same problem. A mutation contributing to a heat tolerance adaptation in Senepol cattle, a New World breed of mostly European descent, results in the distinct phenotype known as slick, where an animal has shorter hair and lower follicle density across its coat than wild type animals. The causal variant, located in the 11th exon of prolactin receptor, produces a frameshift that results in a truncated protein. However, this mutation does not explain all cases of slick coats found in criollo breeds. Here, we obtained genome sequences from slick cattle of a geographically distinct criollo breed, namely Limonero, whose ancestors were originally brought to the Americas by the Spanish. These data were used to identify new causal alleles in the 11th exon of the prolactin receptor, two of which also encode shortened proteins that remove a highly conserved tyrosine residue. These new mutations explained almost 90% of investigated cases of animals that had slick coats, but which also did not carry the Senepol slick allele. These results demonstrate convergent evolution at the molecular level in a trait important to the adaptation of an animal to its environment.

Productivity convergence and spatial dependence among Spanish regions

NARCIS (Netherlands)

Dall'erba, S.D.

2005-01-01

This paper estimates the evolution of labor productivity disparities among 48 Spanish regions over 1980-1996 according to the concepts of β- and σ-convergence. The results of β-convergence emphasize the importance of including the impact of neighboring locations' productivity and a disaggregate

Convergent evolution of vascular optimization in kelp (Laminariales).

Science.gov (United States)

Drobnitch, Sarah Tepler; Jensen, Kaare H; Prentice, Paige; Pittermann, Jarmila

2015-10-07

Terrestrial plants and mammals, although separated by a great evolutionary distance, have each arrived at a highly conserved body plan in which universal allometric scaling relationships govern the anatomy of vascular networks and key functional metabolic traits. The universality of allometric scaling suggests that these phyla have each evolved an 'optimal' transport strategy that has been overwhelmingly adopted by extant species. To truly evaluate the dominance and universality of vascular optimization, however, it is critical to examine other, lesser-known, vascularized phyla. The brown algae (Phaeophyceae) are one such group--as distantly related to plants as mammals, they have convergently evolved a plant-like body plan and a specialized phloem-like transport network. To evaluate possible scaling and optimization in the kelp vascular system, we developed a model of optimized transport anatomy and tested it with measurements of the giant kelp, Macrocystis pyrifera, which is among the largest and most successful of macroalgae. We also evaluated three classical allometric relationships pertaining to plant vascular tissues with a diverse sampling of kelp species. Macrocystis pyrifera displays strong scaling relationships between all tested vascular parameters and agrees with our model; other species within the Laminariales display weak or inconsistent vascular allometries. The lack of universal scaling in the kelps and the presence of optimized transport anatomy in M. pyrifera raises important questions about the evolution of optimization and the possible competitive advantage conferred by optimized vascular systems to multicellular phyla. © 2015 The Author(s).

On sets of convergence and divergence of multiple orthogonal series

International Nuclear Information System (INIS)

D'yachenko, M I; Kazaryan, K S

2002-01-01

Multiple Fourier series with respect to uniformly bounded orthonormal systems (ONSs) are studied. The following results are obtained. Theorem 1. Let Φ={φ n (x)} n=1 ∞ be a complete orthonormal system on [0,1] that is uniformly bounded by M on this interval, assume that m≥2, and let Φ(m)={φ n (x)} nelement ofN m , where φ n (n)=φ n 1 (x 1 )...φ n m (x m ). Then there exists a function f(x) element of L([0,1] m ) cubically diverges on some measurable subset H of [0,1] m with μ m (H)≥1-(1-1/M 2 ) m . Theorem 3. For M>1 and an integer m≥2 let E be an arbitrary measurable subset of [0,1] such that μ(E)=1-1/M 2 . Then there exists a complete orthonormal system Φ on [0,1] uniformly bounded by M there such that the multiple Fourier series of each function f(x) element of L([0,1] m ) with respect to the product system Φ(m) cubically converges to f(x) a.e. on E m . Definitive results in this direction are established also for incomplete uniformly bounded ONSs

Tempo and mode of performance evolution across multiple independent origins of adhesive toe pads in lizards.

Science.gov (United States)

Hagey, Travis J; Uyeda, Josef C; Crandell, Kristen E; Cheney, Jorn A; Autumn, Kellar; Harmon, Luke J

2017-10-01

Understanding macroevolutionary dynamics of trait evolution is an important endeavor in evolutionary biology. Ecological opportunity can liberate a trait as it diversifies through trait space, while genetic and selective constraints can limit diversification. While many studies have examined the dynamics of morphological traits, diverse morphological traits may yield the same or similar performance and as performance is often more proximately the target of selection, examining only morphology may give an incomplete understanding of evolutionary dynamics. Here, we ask whether convergent evolution of pad-bearing lizards has followed similar evolutionary dynamics, or whether independent origins are accompanied by unique constraints and selective pressures over macroevolutionary time. We hypothesized that geckos and anoles each have unique evolutionary tempos and modes. Using performance data from 59 species, we modified Brownian motion (BM) and Ornstein-Uhlenbeck (OU) models to account for repeated origins estimated using Bayesian ancestral state reconstructions. We discovered that adhesive performance in geckos evolved in a fashion consistent with Brownian motion with a trend, whereas anoles evolved in bounded performance space consistent with more constrained evolution (an Ornstein-Uhlenbeck model). Our results suggest that convergent phenotypes can have quite distinctive evolutionary patterns, likely as a result of idiosyncratic constraints or ecological opportunities. © 2017 The Author(s). Evolution © 2017 The Society for the Study of Evolution.

Spatial evolution of Zagros collision zone in Kurdistan - NW Iran, constraints for Arabia-Eurasia oblique convergence

Science.gov (United States)

Sadeghi, S.; Yassaghi, A.

2015-09-01

Stratigraphy, detailed structural mapping and crustal scale cross section of the NW Zagros collision zone evolved during convergence of the Arabian and Eurasian plates were conducted to constrain the spatial evolution of the belt oblique convergence since Late Cretaceous. Zagros orogeny in NW Iran consists of the Sanandaj-Sirjan, Gaveh Rud and ophiolite zones as internal, and Bisotoun, Radiolarite and High Zagros zones as external parts. The Main Zagros Thrust is known as major structures of the Zagros suture zone. Two stages of deformation are recognized in the external parts of Zagros. In the early stage, presence of dextrally deformed domains beside the reversely deformed domains in the Radiolarite zone as well as dextral-reverse faults in both Bisotoun and Radiolarite zones demonstrates partitioning of the dextral transpression. In the late stage, southeastward propagation of the Zagros orogeny towards its foreland resulted in synchronous development of orogen-parallel strike-slip and pure thrust faults. It is proposed that the first stage related to the late Cretaceous oblique obduction, and the second stage is resulted from Cenozoic collision. Cenozoic orogen-parallel strike-slip component of Zagros oblique faulting is not confined to the Zagros suture zone (Main Recent) but also occurred in the more external part (Marekhil-Ravansar fault system). Thus, it is proposed that oblique convergence of Arabia-Eurasia plates occurred in Zagros collision zone since the Late Cretaceous.

Differential evolution-simulated annealing for multiple sequence alignment

Science.gov (United States)

Addawe, R. C.; Addawe, J. M.; Sueño, M. R. K.; Magadia, J. C.

2017-10-01

Multiple sequence alignments (MSA) are used in the analysis of molecular evolution and sequence structure relationships. In this paper, a hybrid algorithm, Differential Evolution - Simulated Annealing (DESA) is applied in optimizing multiple sequence alignments (MSAs) based on structural information, non-gaps percentage and totally conserved columns. DESA is a robust algorithm characterized by self-organization, mutation, crossover, and SA-like selection scheme of the strategy parameters. Here, the MSA problem is treated as a multi-objective optimization problem of the hybrid evolutionary algorithm, DESA. Thus, we name the algorithm as DESA-MSA. Simulated sequences and alignments were generated to evaluate the accuracy and efficiency of DESA-MSA using different indel sizes, sequence lengths, deletion rates and insertion rates. The proposed hybrid algorithm obtained acceptable solutions particularly for the MSA problem evaluated based on the three objectives.

Grasping convergent evolution in syngnathids: a unique tale of tails

Science.gov (United States)

Neutens, C; Adriaens, D; Christiaens, J; De Kegel, B; Dierick, M; Boistel, R; Van Hoorebeke, L

2014-01-01

Seahorses and pipehorses both possess a prehensile tail, a unique characteristic among teleost fishes, allowing them to grasp and hold onto substrates such as sea grasses. Although studies have focused on tail grasping, the pattern of evolutionary transformations that made this possible is poorly understood. Recent phylogenetic studies show that the prehensile tail evolved independently in different syngnathid lineages, including seahorses, Haliichthys taeniophorus and several types of so-called pipehorses. This study explores the pattern that characterizes this convergent evolution towards a prehensile tail, by comparing the caudal musculoskeletal organization, as well as passive bending capacities in pipefish (representing the ancestral state), pipehorse, seahorse and H. taeniophorus. To study the complex musculoskeletal morphology, histological sectioning, μCT-scanning and phase contrast synchrotron scanning were combined with virtual 3D-reconstructions. Results suggest that the independent evolution towards tail grasping in syngnathids reflects at least two quite different strategies in which the ancestral condition of a heavy plated and rigid system became modified into a highly flexible one. Intermediate skeletal morphologies (between the ancestral condition and seahorses) could be found in the pygmy pipehorses and H. taeniophorus, which are phylogenetically closely affiliated with seahorses. This study suggests that the characteristic parallel myoseptal organization as already described in seahorse (compared with a conical organization in pipefish and pipehorse) may not be a necessity for grasping, but represents an apomorphy for seahorses, as this pattern is not found in other syngnathid species possessing a prehensile tail. One could suggest that the functionality of grasping evolved before the specialized, parallel myoseptal organization seen in seahorses. However, as the grasping system in pipehorses is a totally different one, this cannot be

Convergent evolution of pregnancy-specific glycoproteins in human and horse.

Science.gov (United States)

Aleksic, Denis; Blaschke, Lisa; Mißbach, Sophie; Hänske, Jana; Weiß, Wiebke; Handler, Johannes; Zimmermann, Wolfgang; Cabrera-Sharp, Victoria; Read, Jordan E; de Mestre, Amanda M; O'Riordan, Ronan; Moore, Tom; Kammerer, Robert

2016-09-01

Pregnancy-specific glycoproteins (PSGs) are members of the carcinoembryonic antigen cell adhesion molecule (CEACAM) family that are secreted by trophoblast cells. PSGs may modulate immune, angiogenic and platelet responses during pregnancy. Until now, PSGs are only found in species that have a highly invasive (hemochorial) placentation including humans, mice and rats. Surprisingly, analyzing the CEACAM gene family of the horse, which has a non-invasive epitheliochorial placenta, with the exception of the transient endometrial cups, we identified equine CEACAM family members that seem to be related to PSGs of rodents and primates. We identified seven genes that encode secreted PSG-like CEACAMs Phylogenetic analyses indicate that they evolved independently from an equine CEACAM1-like ancestor rather than from a common PSG-like ancestor with rodents and primates. Significantly, expression of PSG-like genes (CEACAM44, CEACAM48, CEACAM49 and CEACAM55) was found in non-invasive as well as invasive trophoblast cells such as purified chorionic girdle cells and endometrial cup cells. Chorionic girdle cells are highly invasive trophoblast cells that invade the endometrium of the mare where they form endometrial cups and are in close contact with maternal immune cells. Therefore, the microenvironment of invasive equine trophoblast cells has striking similarities to the microenvironment of trophoblast cells in hemochorial placentas, suggesting that equine PSG-like CEACAMs and rodent and primate PSGs have undergone convergent evolution. This is supported by our finding that equine PSG-like CEACAM49 exhibits similar activity to certain rodent and human PSGs in a functional assay of platelet-fibrinogen binding. Our results have implications for understanding the evolution of PSGs and their functions in maternal-fetal interactions. © 2016 Society for Reproduction and Fertility.

Stasis and convergence characterize morphological evolution in eupolypod II ferns.

Science.gov (United States)

Sundue, Michael A; Rothfels, Carl J

2014-01-01

Patterns of morphological evolution at levels above family rank remain underexplored in the ferns. The present study seeks to address this gap through analysis of 79 morphological characters for 81 taxa, including representatives of all ten families of eupolypod II ferns. Recent molecular phylogenetic studies demonstrate that the evolution of the large eupolypod II clade (which includes nearly one-third of extant fern species) features unexpected patterns. The traditional 'athyrioid' ferns are scattered across the phylogeny despite their apparent morphological cohesiveness, and mixed among these seemingly conservative taxa are morphologically dissimilar groups that lack any obvious features uniting them with their relatives. Maximum-likelihood and maximum-parsimony character optimizations are used to determine characters that unite the seemingly disparate groups, and to test whether the polyphyly of the traditional athyrioid ferns is due to evolutionary stasis (symplesiomorphy) or convergent evolution. The major events in eupolypod II character evolution are reviewed, and character and character state concepts are reappraised, as a basis for further inquiries into fern morphology. Characters were scored from the literature, live plants and herbarium specimens, and optimized using maximum-parsimony and maximum-likelihood, onto a highly supported topology derived from maximum-likelihood and Bayesian analysis of molecular data. Phylogenetic signal of characters were tested for using randomization methods and fitdiscrete. The majority of character state changes within the eupolypod II phylogeny occur at the family level or above. Relative branch lengths for the morphological data resemble those from molecular data and fit an ancient rapid radiation model (long branches subtended by very short backbone internodes), with few characters uniting the morphologically disparate clades. The traditional athyrioid ferns were circumscribed based upon a combination of

Time evolution of multiple quantum coherences in NMR

International Nuclear Information System (INIS)

Sanchez, Claudia M.; Pastawski, Horacio M.; Levstein, Patricia R.

2007-01-01

In multiple quantum NMR, individual spins become correlated with one another over time through their dipolar couplings. In this way, the usual Zeeman selection rule can be overcome and forbidden transitions can be excited. Experimentally, these multiple quantum coherences (MQC) are formed by the application of appropriate sequences of radio frequency pulses that force the spins to act collectively. 1 H spin coherences of even order up to 16 were excited in a polycrystalline sample of ferrocene (C 5 H 5 ) 2 Fe and up to 32 in adamantane (C 10 H 16 ) and their evolutions studied in different conditions: (a) under the natural dipolar Hamiltonian, H ZZ (free evolution) and with H ZZ canceled out by (b) time reversion or (c) with the MREV8 sequence. The results show that when canceling H ZZ the coherences decay with characteristic times (τ c ∼200 μs), which are more than one order of magnitude longer than those under free evolution (τ c ∼10 μs). In addition, it is observed that with both MREV8 and time reversion sequences, the higher the order of the coherence (larger number of correlated spins) the faster the speed of degradation, as it happens during the evolution with H ZZ . In both systems, it is observed that the sequence of time reversion of the dipolar Hamiltonian preserves coherences for longer times than MREV8

Confidence building on euro convergence : Evidence from currency options

NARCIS (Netherlands)

Driessen, J.J.A.G.; Perotti, E.

2011-01-01

We study the evolution of investor confidence in 1992–1998 over the chance of individual currencies to converge to the Euro, using data on currency option prices. Convergence risk, which may reflect uncertainty over policy commitment as well as exogenous fundamentals, induces a level of implied

Confidence building on Euro convergence: evidence from currency options

NARCIS (Netherlands)

Driessen, J.; Perotti, E.

2011-01-01

We study the evolution of investor confidence in 1992-1998 over the chance of individual currencies to converge to the Euro, using data on currency option prices. Convergence risk, which may reflect uncertainty over policy commitment as well as exogenous fundamentals, induces a level of implied

Convergent evolution of chromosomal sex-determining regions in the animal and fungal kingdoms.

Directory of Open Access Journals (Sweden)

James A Fraser

2004-12-01

Full Text Available Sexual identity is governed by sex chromosomes in plants and animals, and by mating type (MAT loci in fungi. Comparative analysis of the MAT locus from a species cluster of the human fungal pathogen Cryptococcus revealed sequential evolutionary events that fashioned this large, highly unusual region. We hypothesize that MAT evolved via four main steps, beginning with acquisition of genes into two unlinked sex-determining regions, forming independent gene clusters that then fused via chromosomal translocation. A transitional tripolar intermediate state then converted to a bipolar system via gene conversion or recombination between the linked and unlinked sex-determining regions. MAT was subsequently subjected to intra- and interallelic gene conversion and inversions that suppress recombination. These events resemble those that shaped mammalian sex chromosomes, illustrating convergent evolution in sex-determining structures in the animal and fungal kingdoms.

A new horned dinosaur reveals convergent evolution in cranial ornamentation in Ceratopsidae.

Science.gov (United States)

Brown, Caleb M; Henderson, Donald M

2015-06-15

Ceratopsid (horned) dinosaurs are an iconic group of large-bodied, quadrupedal, herbivorous dinosaurs that evolved in the Late Cretaceous and were largely restricted to western North America [1-5]. Ceratopsids are easily recognized by their cranial ornamentation in the form of nasal and postorbital horns and frill (capped by epiossifications); these structures show high morphological disparity and also represent the largest cranial display structures known to have evolved [2, 4]. Despite their restricted occurrence in time and space, this group has one of the best fossil records within Dinosauria, showing a rapid diversification in horn and frill morphology [1]. Here a new genus and species of chasmosaurine ceratopsid is described based on a nearly complete and three-dimensionally preserved cranium recovered from the uppermost St. Mary River Formation (Maastrichtian) of southwestern Alberta. Regaliceratops peterhewsi gen. et sp. nov. exhibits many unique characters of the frill and is characterized by a large nasal horncore, small postorbital horncores, and massive parietal epiossifications. Cranial morphology, particularly the epiossifications, suggests close affinity with the late Campanian/early Maastrichian taxon Anchiceratops, as well as with the late Maastrichtian taxon Triceratops. A median epiparietal necessitates a reassessment of epiossification homology and results in a more resolved phylogeny. Most surprisingly, Regaliceratops exhibits a suite of cranial ornamentations that are superficially similar to Campanian centrosaurines, indicating both exploration of novel display morphospace in Chasmosaurinae, especially Maastrichtian forms, and convergent evolution in horn morphology with the recently extinct Centrosaurinae. This marks the first time that evolutionary convergence in horn-like display structures has been demonstrated between dinosaur clades, similar to those seen in fossil and extant mammals [6]. Copyright © 2015 Elsevier Ltd. All rights

Signatures of pleiotropy, economy and convergent evolution in a domain-resolved map of human-virus protein-protein interaction networks.

Science.gov (United States)

Garamszegi, Sara; Franzosa, Eric A; Xia, Yu

2013-01-01

A central challenge in host-pathogen systems biology is the elucidation of general, systems-level principles that distinguish host-pathogen interactions from within-host interactions. Current analyses of host-pathogen and within-host protein-protein interaction networks are largely limited by their resolution, treating proteins as nodes and interactions as edges. Here, we construct a domain-resolved map of human-virus and within-human protein-protein interaction networks by annotating protein interactions with high-coverage, high-accuracy, domain-centric interaction mechanisms: (1) domain-domain interactions, in which a domain in one protein binds to a domain in a second protein, and (2) domain-motif interactions, in which a domain in one protein binds to a short, linear peptide motif in a second protein. Analysis of these domain-resolved networks reveals, for the first time, significant mechanistic differences between virus-human and within-human interactions at the resolution of single domains. While human proteins tend to compete with each other for domain binding sites by means of sequence similarity, viral proteins tend to compete with human proteins for domain binding sites in the absence of sequence similarity. Independent of their previously established preference for targeting human protein hubs, viral proteins also preferentially target human proteins containing linear motif-binding domains. Compared to human proteins, viral proteins participate in more domain-motif interactions, target more unique linear motif-binding domains per residue, and contain more unique linear motifs per residue. Together, these results suggest that viruses surmount genome size constraints by convergently evolving multiple short linear motifs in order to effectively mimic, hijack, and manipulate complex host processes for their survival. Our domain-resolved analyses reveal unique signatures of pleiotropy, economy, and convergent evolution in viral-host interactions that are

A genotype network reveals homoplastic cycles of convergent evolution in influenza A (H3N2) haemagglutinin.

Science.gov (United States)

Wagner, Andreas

2014-07-07

Networks of evolving genotypes can be constructed from the worldwide time-resolved genotyping of pathogens like influenza viruses. Such genotype networks are graphs where neighbouring vertices (viral strains) differ in a single nucleotide or amino acid. A rich trove of network analysis methods can help understand the evolutionary dynamics reflected in the structure of these networks. Here, I analyse a genotype network comprising hundreds of influenza A (H3N2) haemagglutinin genes. The network is rife with cycles that reflect non-random parallel or convergent (homoplastic) evolution. These cycles also show patterns of sequence change characteristic for strong and local evolutionary constraints, positive selection and mutation-limited evolution. Such cycles would not be visible on a phylogenetic tree, illustrating that genotype network analysis can complement phylogenetic analyses. The network also shows a distinct modular or community structure that reflects temporal more than spatial proximity of viral strains, where lowly connected bridge strains connect different modules. These and other organizational patterns illustrate that genotype networks can help us study evolution in action at an unprecedented level of resolution. © 2014 The Author(s) Published by the Royal Society. All rights reserved.

Deadly hairs, lethal feathers--convergent evolution of poisonous integument in mammals and birds.

Science.gov (United States)

Plikus, Maksim V; Astrowski, Aliaksandr A

2014-07-01

Hairs and feathers are textbook examples of the convergent evolution of the follicular appendage structure between mammals and birds. While broadly recognized for their convergent thermoregulatory, camouflage and sexual display functions, hairs and feathers are rarely thought of as deadly defence tools. Several recent studies, however, show that in some species of mammals and birds, the integument can, in fact, be a de facto lethal weapon. One mammalian example is provided by African crested rats, which seek for and chew on the bark of plants containing the highly potent toxin, ouabain. These rats then coat their fur with ouabain-containing saliva. For efficient toxin retention, the rodents have evolved highly specialized fenestrated and mostly hollow hair shafts that soak up liquids, which essentially function as wicks. On the avian side of the vertebrate integumental variety spectrum, several species of birds of New Guinea have evolved resistance to highly potent batrachotoxins, which they acquire from their insect diet. While the mechanism of bird toxicity remains obscure, in a recently published issue of the journal, Dumbacher and Menon explore the intriguing idea that to achieve efficient storage of batrachotoxins in their skin, some birds exploit the basic permeability barrier function of their epidermis. Batrachotoxins become preferentially sequestered in their epidermis and are then transferred to feathers, likely through the exploitation of specialized avian lipid-storing multigranular body organelles. Here, we discuss wider implications of this intriguing concept. © 2014 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

Data set incongruence and correlated character evolution: An example of functional convergence in the hind-limbs of stifftail diving ducks

Science.gov (United States)

McCracken, K.G.; Harshman, J.; Mcclellan, D.A.; Afton, A.D.

1999-01-01

The unwitting inclusion of convergent characters in phylogenetic estimates poses a serious problem for efforts to recover phylogeny. Convergence is not inscrutable, however, particularly when one group of characters tracks phylogeny and another set tracks adaptive history. In such cases, convergent characters may be correlated with one or a few functional anatomical units and readily identifiable by using comparative methods. Stifftail ducks (Oxyurinae) offer one such opportunity to study correlated character evolution and function in the context of phylogenetic reconstruction. Morphological analyses place stifftail ducks as part of a large clade of diving ducks that includes the sea ducks (Mergini), Hymenolaimus, Merganetta, and Tachyeres, and possibly the pochards (Aythyini). Molecular analyses, on the other hand, place stifftails far from other diving ducks and suggest, moreover, that stifftails are polyphyletic. Mitochondrial cytochrome b gene sequences of eight stifftail species traditionally supposed to form a clade were compared with each other and with sequences from 50 other anseriform and galliform species. Stifftail ducks are not the sister group of sea ducks but lie outside the typical ducks (Anatinae). Of the four traditional stifftail genera, monophyly of Oxyura and its sister group relationship with Nomonyx are strongly supported. Heteronetta probably is the sister group of that clade, but support is weak. Biziura is not a true stifftail. Within Oxyura, Old World species (O. australis, O. leucocephala, O. mnccoa) appear to form a clade, with New World species (O. jamaicensis, O. vittata) branching basally. Incongruence between molecules and morphology is interpreted to be the result of adaptive specialization and functional convergence in the hind limbs of Biziura and true stifftails. When morphological characters are divided into classes, only hind-limb characters are significantly in conflict with the molecular tree. Likewise, null models of

Molecular mechanisms involved in convergent crop domestication.

Science.gov (United States)

Lenser, Teresa; Theißen, Günter

2013-12-01

Domestication has helped to understand evolution. We argue that, vice versa, novel insights into evolutionary principles could provide deeper insights into domestication. Molecular analyses have demonstrated that convergent phenotypic evolution is often based on molecular changes in orthologous genes or pathways. Recent studies have revealed that during plant domestication the causal mutations for convergent changes in key traits are likely to be located in particular genes. These insights may contribute to defining candidate genes for genetic improvement during the domestication of new plant species. Such efforts may help to increase the range of arable crops available, thus increasing crop biodiversity and food security to help meet the predicted demands of the continually growing global population under rapidly changing environmental conditions. Copyright © 2013 Elsevier Ltd. All rights reserved.

Convergent evolution of hemoglobin switching in jawed and jawless vertebrates.

Science.gov (United States)

Rohlfing, Kim; Stuhlmann, Friederike; Docker, Margaret F; Burmester, Thorsten

2016-02-01

During development, humans and other jawed vertebrates (Gnathostomata) express distinct hemoglobin genes, resulting in different hemoglobin tetramers. Embryonic and fetal hemoglobin have higher oxygen affinities than the adult hemoglobin, sustaining the oxygen demand of the developing organism. Little is known about the expression of hemoglobins during development of jawless vertebrates (Agnatha). We identified three hemoglobin switches in the life cycle of the sea lamprey. Three hemoglobin genes are specifically expressed in the embryo, four genes in the filter feeding larva (ammocoete), and nine genes correspond to the adult hemoglobin chains. During the development from the parasitic to the reproductive adult, the composition of hemoglobin changes again, with a massive increase of chain aHb1. A single hemoglobin chain is expressed constitutively in all stages. We further showed the differential expression of other globin genes: Myoglobin 1 is most highly expressed in the reproductive adult, myoglobin 2 expression peaks in the larva. Globin X1 is restricted to the embryo; globin X2 was only found in the reproductive adult. Cytoglobin is expressed at low levels throughout the life cycle. Because the hemoglobins of jawed and jawless vertebrates evolved independently from a common globin ancestor, hemoglobin switching must also have evolved convergently in these taxa. Notably, the ontogeny of sea lamprey hemoglobins essentially recapitulates their phylogeny, with the embryonic hemoglobins emerging first, followed by the evolution of larval and adult hemoglobins.

Time evolution and use of multiple times in the N-body problem

International Nuclear Information System (INIS)

McGuire, J.H.; Godunov, A.L.

2003-01-01

Under certain conditions it is possible to describe time evolution using different times for different particles. Use of multiple times is optional in the independent particle approximation, where interparticle interactions are removed, and the N-particle evolution operator factors into N single-particle evolution operators. In this limit one may use either a single time, with a single energy-time Fourier transform, or N different times with a different energy-time transform for each particle. The use of different times for different particles is fully justified when coherence between single-particle amplitudes is lost, e.g., if relatively strong randomly fluctuating residual fields influence each particle independently. However, when spatial correlation is present the use of multiple times is not feasible, even when the evolution of the particles is uncorrelated in time. Some calculations in simple atomic systems with and without spatial and temporal correlation between different electrons are included

Relatively Inexact Proximal Point Algorithm and Linear Convergence Analysis

Directory of Open Access Journals (Sweden)

Ram U. Verma

2009-01-01

Full Text Available Based on a notion of relatively maximal (m-relaxed monotonicity, the approximation solvability of a general class of inclusion problems is discussed, while generalizing Rockafellar's theorem (1976 on linear convergence using the proximal point algorithm in a real Hilbert space setting. Convergence analysis, based on this new model, is simpler and compact than that of the celebrated technique of Rockafellar in which the Lipschitz continuity at 0 of the inverse of the set-valued mapping is applied. Furthermore, it can be used to generalize the Yosida approximation, which, in turn, can be applied to first-order evolution equations as well as evolution inclusions.

Confidence building on euro convergence: theory and evidence from currency options

NARCIS (Netherlands)

Driessen, J.; Perotti, E.

2003-01-01

Using a new dataset of currency option prices, we study the evolution of investor confidence in 1992-1998 over the chance of individual currencies to converge to the Euro. Convergence risk, which may reflect uncertainty over policy commitment as well as exogenous fundamentals, induces a level of

Functional traits, convergent evolution, and periodic tables of niches.

Science.gov (United States)

Winemiller, Kirk O; Fitzgerald, Daniel B; Bower, Luke M; Pianka, Eric R

2015-08-01

Ecology is often said to lack general theories sufficiently predictive for applications. Here, we examine the concept of a periodic table of niches and feasibility of niche classification schemes from functional trait and performance data. Niche differences and their influence on ecological patterns and processes could be revealed effectively by first performing data reduction/ordination analyses separately on matrices of trait and performance data compiled according to logical associations with five basic niche 'dimensions', or aspects: habitat, life history, trophic, defence and metabolic. Resultant patterns then are integrated to produce interpretable niche gradients, ordinations and classifications. Degree of scheme periodicity would depend on degrees of niche conservatism and convergence causing species clustering across multiple niche dimensions. We analysed a sample data set containing trait and performance data to contrast two approaches for producing niche schemes: species ordination within niche gradient space, and niche categorisation according to trait-value thresholds. Creation of niche schemes useful for advancing ecological knowledge and its applications will depend on research that produces functional trait and performance datasets directly related to niche dimensions along with criteria for data standardisation and quality. As larger databases are compiled, opportunities will emerge to explore new methods for data reduction, ordination and classification. © 2015 The Authors. Ecology Letters published by CNRS and John Wiley & Sons Ltd.

Convergence Science in a Nano World

OpenAIRE

Cady, Nathaniel

2013-01-01

Convergence is a new paradigm that brings together critical advances in the life sciences, physical sciences and engineering. Going beyond traditional “interdisciplinary” studies, “convergence” describes the culmination of truly integrated research and development, yielding revolutionary advances in both scientific research and new technologies. At its core, nanotechnology embodies these elements of convergence science by bringing together multiple disciplines with the goal of creating innova...

Rapid divergence and convergence of life-history in experimentally evolved Drosophila melanogaster.

Science.gov (United States)

Burke, Molly K; Barter, Thomas T; Cabral, Larry G; Kezos, James N; Phillips, Mark A; Rutledge, Grant A; Phung, Kevin H; Chen, Richard H; Nguyen, Huy D; Mueller, Laurence D; Rose, Michael R

2016-09-01

Laboratory selection experiments are alluring in their simplicity, power, and ability to inform us about how evolution works. A longstanding challenge facing evolution experiments with metazoans is that significant generational turnover takes a long time. In this work, we present data from a unique system of experimentally evolved laboratory populations of Drosophila melanogaster that have experienced three distinct life-history selection regimes. The goal of our study was to determine how quickly populations of a certain selection regime diverge phenotypically from their ancestors, and how quickly they converge with independently derived populations that share a selection regime. Our results indicate that phenotypic divergence from an ancestral population occurs rapidly, within dozens of generations, regardless of that population's evolutionary history. Similarly, populations sharing a selection treatment converge on common phenotypes in this same time frame, regardless of selection pressures those populations may have experienced in the past. These patterns of convergence and divergence emerged much faster than expected, suggesting that intermediate evolutionary history has transient effects in this system. The results we draw from this system are applicable to other experimental evolution projects, and suggest that many relevant questions can be sufficiently tested on shorter timescales than previously thought. © 2016 The Author(s). Evolution © 2016 The Society for the Study of Evolution.

Widespread ecomorphological convergence in multiple fish families spanning the marine-freshwater interface.

Science.gov (United States)

Davis, Aaron M; Betancur-R, Ricardo

2017-05-17

The theoretical definition and quantification of convergence is an increasingly topical focus in evolutionary research, with particular growing interest on study scales spanning deep phylogenetic divergences and broad geographical areas. While much progress has recently been made in understanding the role of convergence in driving terrestrial (e.g. anole lizards) and aquatic (e.g. cichlids) radiations, little is known about its macroevolutionary effects across environmental gradients. This study uses a suite of recently developed comparative approaches integrating diverse aspects of morphology, dietary data, habitat affiliation and phylogeny to assess convergence across several well-known tropical-temperate fish families in the percomorph suborder Terapontoidei, a clade with considerable phenotypic and ecological diversity radiating in both marine and freshwater environments. We demonstrate significant widespread convergence across many lineages occupying equivalent trophic niches, particularly feeding habits such as herbivory and biting of attached prey off hard substrates. These include several examples of convergent morphotypes evolving independently in marine and freshwater clades, separated by deep evolutionary divergences (tens of millions of years). The Terapontoidei present a new example of the macroevolutionary dynamics of morphological and ecological coevolution in relation to habitat and trophic preferences, at a greater phylogenetic and habitat scale than most well-studied adaptive radiations. © 2017 The Author(s).

SELF-CONVERGENCE OF RADIATIVELY COOLING CLUMPS IN THE INTERSTELLAR MEDIUM

International Nuclear Information System (INIS)

Yirak, Kristopher; Frank, Adam; Cunningham, Andrew J.

2010-01-01

Isolated regions of higher density populate the interstellar medium (ISM) on all scales-from molecular clouds, to the star-forming regions known as cores, to heterogeneous ejecta found near planetary nebulae and supernova remnants. These clumps interact with winds and shocks from nearby energetic sources. Understanding the interactions of shocked clumps is vital to our understanding of the composition, morphology, and evolution of the ISM. The evolution of shocked clumps is well understood in the limiting 'adiabatic' case where physical processes such as self-gravity, heat conduction, radiative cooling, and magnetic fields are ignored. In this paper, we address the issue of evolution and convergence when one of these processes-radiative cooling-is included. Numeric convergence studies demonstrate that the evolution of an adiabatic clump is well captured by roughly 100 cells per clump radius. The presence of radiative cooling, however, imposes limits on the problem due to the removal of thermal energy. Numerical studies which include radiative cooling typically adopt the 100-200 cells per clump radius resolution. In this paper, we present the results of a convergence study for radiatively cooling clumps undertaken over a broad range of resolutions, from 12 to 1536 cells per clump radius, employing adaptive mesh refinement (AMR) in a two-dimensional axisymmetric geometry (2.5 dimensions). We also provide a fully three-dimensional simulation, at 192 cells per clump radius, which supports our 2.5 dimensional results. We find no appreciable self-convergence at ∼100 cells per clump radius as small-scale differences owing to increasingly resolving the cooling length have global effects. We therefore conclude that self-convergence is an insufficient criterion to apply on its own when addressing the question of sufficient resolution for radiatively cooled shocked clump simulations. We suggest the adoption of alternate criteria to support a statement of sufficient

Overcoming Deception in Evolution of Cognitive Behaviors

DEFF Research Database (Denmark)

Lehman, Joel; Miikkulainen, Risto

2014-01-01

When scaling neuroevolution to complex behaviors, cognitive capabilities such as learning, communication, and memory become increasingly important. However, successfully evolving such cognitive abilities remains difficult. This paper argues that a main cause for such difficulty is deception, i.......e. evolution converges to a behavior unrelated to the desired solution. More specifically, cognitive behaviors often require accumulating neural structure that provides no immediate fitness benefit, and evolution often thus converges to non-cognitive solutions. To investigate this hypothesis, a common...... evolutionary robotics T-Maze domain is adapted in three separate ways to require agents to communicate, remember, and learn. Indicative of deception, evolution driven by objective-based fitness often converges upon simple non- cognitive behaviors. In contrast, evolution driven to explore novel behaviors, i...

Signatures of pleiotropy, economy and convergent evolution in a domain-resolved map of human-virus protein-protein interaction networks.

Directory of Open Access Journals (Sweden)

Sara Garamszegi

Full Text Available A central challenge in host-pathogen systems biology is the elucidation of general, systems-level principles that distinguish host-pathogen interactions from within-host interactions. Current analyses of host-pathogen and within-host protein-protein interaction networks are largely limited by their resolution, treating proteins as nodes and interactions as edges. Here, we construct a domain-resolved map of human-virus and within-human protein-protein interaction networks by annotating protein interactions with high-coverage, high-accuracy, domain-centric interaction mechanisms: (1 domain-domain interactions, in which a domain in one protein binds to a domain in a second protein, and (2 domain-motif interactions, in which a domain in one protein binds to a short, linear peptide motif in a second protein. Analysis of these domain-resolved networks reveals, for the first time, significant mechanistic differences between virus-human and within-human interactions at the resolution of single domains. While human proteins tend to compete with each other for domain binding sites by means of sequence similarity, viral proteins tend to compete with human proteins for domain binding sites in the absence of sequence similarity. Independent of their previously established preference for targeting human protein hubs, viral proteins also preferentially target human proteins containing linear motif-binding domains. Compared to human proteins, viral proteins participate in more domain-motif interactions, target more unique linear motif-binding domains per residue, and contain more unique linear motifs per residue. Together, these results suggest that viruses surmount genome size constraints by convergently evolving multiple short linear motifs in order to effectively mimic, hijack, and manipulate complex host processes for their survival. Our domain-resolved analyses reveal unique signatures of pleiotropy, economy, and convergent evolution in viral

New concurrent iterative methods with monotonic convergence

Energy Technology Data Exchange (ETDEWEB)

Yao, Qingchuan [Michigan State Univ., East Lansing, MI (United States)

1996-12-31

This paper proposes the new concurrent iterative methods without using any derivatives for finding all zeros of polynomials simultaneously. The new methods are of monotonic convergence for both simple and multiple real-zeros of polynomials and are quadratically convergent. The corresponding accelerated concurrent iterative methods are obtained too. The new methods are good candidates for the application in solving symmetric eigenproblems.

Fractal aspects and convergence of Newton`s method

Energy Technology Data Exchange (ETDEWEB)

Drexler, M. [Oxford Univ. Computing Lab. (United Kingdom)

1996-12-31

Newton`s Method is a widely established iterative algorithm for solving non-linear systems. Its appeal lies in its great simplicity, easy generalization to multiple dimensions and a quadratic local convergence rate. Despite these features, little is known about its global behavior. In this paper, we will explain a seemingly random global convergence pattern using fractal concepts and show that the behavior of the residual is entirely explicable. We will also establish quantitative results for the convergence rates. Knowing the mechanism of fractal generation, we present a stabilization to the orthodox Newton method that remedies the fractal behavior and improves convergence.

An Ensemble Approach in Converging Contents of LMS and KMS

Science.gov (United States)

Sabitha, A. Sai; Mehrotra, Deepti; Bansal, Abhay

2017-01-01

Currently the challenges in e-Learning are converging the learning content from various sources and managing them within e-learning practices. Data mining learning algorithms can be used and the contents can be converged based on the Metadata of the objects. Ensemble methods use multiple learning algorithms and it can be used to converge the…

Convergence between power and gas industries: evolution and perspectives in Spain

International Nuclear Information System (INIS)

Munoz Rueda, J. J.

2007-01-01

Convergence between power and gas industries in spain has already become very important, and it will be even more in the future, as the installed capacity in combined cycles will increase as expected, and tariff distortions, that have blocked commercialization development, could be eliminated. Convergence of both businesses signals the necessity to approach a series of key questions for an efficient operation of both markets that guarantees a reasonable level of competition to assure a fair treatment among gas and power operators that will also produce more added value for clients. (Author)

Evolution Procedure of Multiple Rock Cracks under Seepage Pressure

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Taoying Liu

2013-01-01

Full Text Available In practical geotechnical engineering, most of rock masses with multiple cracks exist in water environment. Under such circumstance, these adjacent cracks could interact with each other. Moreover, the seepage pressure, produced by the high water pressure, can change cracks’ status and have an impact on the stress state of fragile rocks. According to the theory of fracture mechanics, this paper discusses the law of crack initiation and the evolution law of stress intensity factor at the tip of a wing crack caused by compression-shear stress and seepage pressure. Subsequently, considering the interaction of the wing cracks and the additional stress caused by rock bridge damage, this paper proposes the intensity factor evolution equation under the combined action of compression-shear stress and seepage pressure. In addition, this paper analyzes the propagation of cracks under different seepage pressure which reveals that the existence of seepage pressure facilitates the wing crack’s growth. The result indicates that the high seepage pressure converts wing crack growth from stable form to unstable form. Meanwhile, based on the criterion and mechanism for crack initiation and propagation, this paper puts forward the mechanical model for different fracture transfixion failure modes of the crag bridge under the combined action of seepage pressure and compression-shear stress. At the last part, this paper, through investigating the flexibility tensor of the rock mass’s initial damage and its damage evolution in terms of jointed rock mass's damage mechanics, deduces the damage evolution equation for the rock mass with multiple cracks under the combined action of compression-shear stress and seepage pressure. The achievement of this investigation provides a reliable theoretical principle for quantitative research of the fractured rock mass failure under seepage pressure.

Albania and the EU: A path to convergence?

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Javier Lopez-Prol

2014-11-01

Full Text Available The aim of this paper is to assess the degree of relative convergence achieved by Albania in relation to the EU during the last decade through a descriptive empirical analysis. The paper is divided into three sections related to real and nominal convergence in the fields of economic performance; trade openness and balance; and monetary convergence, according to the Euro criteria established in the art. 140 (1 of the TFEU and the protocol Nº 13 (price stability, public finances, exchange rate, and long-term interest rates. In order to have a wide perspective about convergence-divergence trends inside and outside the EU, the tendencies followed by Germany and Greece are also mentioned, as paradigmatic cases of divergence within the EU. Finally, a summary table is presented reviewing each of the analysed variables regarding the last decade evolution and the current situation.

The Convergence Problems of Eigenfunction Expansions of Elliptic Differential Operators

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Ahmedov, Anvarjon

2018-03-01

In the present research we investigate the problems concerning the almost everywhere convergence of multiple Fourier series summed over the elliptic levels in the classes of Liouville. The sufficient conditions for the almost everywhere convergence problems, which are most difficult problems in Harmonic analysis, are obtained. The methods of approximation by multiple Fourier series summed over elliptic curves are applied to obtain suitable estimations for the maximal operator of the spectral decompositions. Obtaining of such estimations involves very complicated calculations which depends on the functional structure of the classes of functions. The main idea on the proving the almost everywhere convergence of the eigenfunction expansions in the interpolation spaces is estimation of the maximal operator of the partial sums in the boundary classes and application of the interpolation Theorem of the family of linear operators. In the present work the maximal operator of the elliptic partial sums are estimated in the interpolation classes of Liouville and the almost everywhere convergence of the multiple Fourier series by elliptic summation methods are established. The considering multiple Fourier series as an eigenfunction expansions of the differential operators helps to translate the functional properties (for example smoothness) of the Liouville classes into Fourier coefficients of the functions which being expanded into such expansions. The sufficient conditions for convergence of the multiple Fourier series of functions from Liouville classes are obtained in terms of the smoothness and dimensions. Such results are highly effective in solving the boundary problems with periodic boundary conditions occurring in the spectral theory of differential operators. The investigations of multiple Fourier series in modern methods of harmonic analysis incorporates the wide use of methods from functional analysis, mathematical physics, modern operator theory and spectral

Mosaic convergence of rodent dentitions.

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Vincent Lazzari

Full Text Available BACKGROUND: Understanding mechanisms responsible for changes in tooth morphology in the course of evolution is an area of investigation common to both paleontology and developmental biology. Detailed analyses of molar tooth crown shape have shown frequent homoplasia in mammalian evolution, which requires accurate investigation of the evolutionary pathways provided by the fossil record. The necessity of preservation of an effective occlusion has been hypothesized to functionally constrain crown morphological changes and to also facilitate convergent evolution. The Muroidea superfamily constitutes a relevant model for the study of molar crown diversification because it encompasses one third of the extant mammalian biodiversity. METHODOLOGY/PRINCIPAL FINDINGS: Combined microwear and 3D-topographic analyses performed on fossil and extant muroid molars allow for a first quantification of the relationships between changes in crown morphology and functionality of occlusion. Based on an abundant fossil record and on a well resolved phylogeny, our results show that the most derived functional condition associates longitudinal chewing and non interlocking of cusps. This condition has been reached at least 7 times within muroids via two main types of evolutionary pathways each respecting functional continuity. In the first type, the flattening of tooth crown which induces the removal of cusp interlocking occurs before the rotation of the chewing movement. In the second type however, flattening is subsequent to rotation of the chewing movement which can be associated with certain changes in cusp morphology. CONCLUSION/SIGNIFICANCE: The reverse orders of the changes involved in these different pathways reveal a mosaic evolution of mammalian dentition in which direction of chewing and crown shape seem to be partly decoupled. Either can change in respect to strong functional constraints affecting occlusion which thereby limit the number of the possible

Self-similar dynamic converging shocks - I. An isothermal gas sphere with self-gravity

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Lou, Yu-Qing; Shi, Chun-Hui

2014-07-01

We explore novel self-similar dynamic evolution of converging spherical shocks in a self-gravitating isothermal gas under conceivable astrophysical situations. The construction of such converging shocks involves a time-reversal operation on feasible flow profiles in self-similar expansion with a proper care for the increasing direction of the specific entropy. Pioneered by Guderley since 1942 but without self-gravity so far, self-similar converging shocks are important for implosion processes in aerodynamics, combustion, and inertial fusion. Self-gravity necessarily plays a key role for grossly spherical structures in very broad contexts of astrophysics and cosmology, such as planets, stars, molecular clouds (cores), compact objects, planetary nebulae, supernovae, gamma-ray bursts, supernova remnants, globular clusters, galactic bulges, elliptical galaxies, clusters of galaxies as well as relatively hollow cavity or bubble structures on diverse spatial and temporal scales. Large-scale dynamic flows associated with such quasi-spherical systems (including collapses, accretions, fall-backs, winds and outflows, explosions, etc.) in their initiation, formation, and evolution are likely encounter converging spherical shocks at times. Our formalism lays an important theoretical basis for pertinent astrophysical and cosmological applications of various converging shock solutions and for developing and calibrating numerical codes. As examples, we describe converging shock triggered star formation, supernova explosions, and void collapses.

Three-phase Interstellar Medium in Galaxies Resolving Evolution with Star Formation and Supernova Feedback (TIGRESS): Algorithms, Fiducial Model, and Convergence

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Kim, Chang-Goo; Ostriker, Eve C.

2017-09-01

We introduce TIGRESS, a novel framework for multi-physics numerical simulations of the star-forming interstellar medium (ISM) implemented in the Athena MHD code. The algorithms of TIGRESS are designed to spatially and temporally resolve key physical features, including: (1) the gravitational collapse and ongoing accretion of gas that leads to star formation in clusters; (2) the explosions of supernovae (SNe), both near their progenitor birth sites and from runaway OB stars, with time delays relative to star formation determined by population synthesis; (3) explicit evolution of SN remnants prior to the onset of cooling, which leads to the creation of the hot ISM; (4) photoelectric heating of the warm and cold phases of the ISM that tracks the time-dependent ambient FUV field from the young cluster population; (5) large-scale galactic differential rotation, which leads to epicyclic motion and shears out overdense structures, limiting large-scale gravitational collapse; (6) accurate evolution of magnetic fields, which can be important for vertical support of the ISM disk as well as angular momentum transport. We present tests of the newly implemented physics modules, and demonstrate application of TIGRESS in a fiducial model representing the solar neighborhood environment. We use a resolution study to demonstrate convergence and evaluate the minimum resolution {{Δ }}x required to correctly recover several ISM properties, including the star formation rate, wind mass-loss rate, disk scale height, turbulent and Alfvénic velocity dispersions, and volume fractions of warm and hot phases. For the solar neighborhood model, all these ISM properties are converged at {{Δ }}x≤slant 8 {pc}.

Do convergent developmental mechanisms underlie convergent phenotypes?

Science.gov (United States)

Wray, Gregory A.

2002-01-01

Convergence is a pervasive evolutionary process, affecting many aspects of phenotype and even genotype. Relatively little is known about convergence in developmental processes, however, nor about the degree to which convergence in development underlies convergence in anatomy. A switch in the ecology of sea urchins from feeding to nonfeeding larvae illustrates how convergence in development can be associated with convergence in anatomy. Comparisons to more distantly related taxa, however, suggest that this association may be limited to relatively close phylogenetic comparisons. Similarities in gene expression during development provide another window into the association between convergence in developmental processes and convergence in anatomy. Several well-studied transcription factors exhibit likely cases of convergent gene expression in distantly related animal phyla. Convergence in regulatory gene expression domains is probably more common than generally acknowledged, and can arise for several different reasons. Copyright 2002 S. Karger AG, Basel.

The first whole genome and transcriptome of the cinereous vulture reveals adaptation in the gastric and immune defense systems and possible convergent evolution between the Old and New World vultures.

Science.gov (United States)

Chung, Oksung; Jin, Seondeok; Cho, Yun Sung; Lim, Jeongheui; Kim, Hyunho; Jho, Sungwoong; Kim, Hak-Min; Jun, JeHoon; Lee, HyeJin; Chon, Alvin; Ko, Junsu; Edwards, Jeremy; Weber, Jessica A; Han, Kyudong; O'Brien, Stephen J; Manica, Andrea; Bhak, Jong; Paek, Woon Kee

2015-10-21

The cinereous vulture, Aegypius monachus, is the largest bird of prey and plays a key role in the ecosystem by removing carcasses, thus preventing the spread of diseases. Its feeding habits force it to cope with constant exposure to pathogens, making this species an interesting target for discovering functionally selected genetic variants. Furthermore, the presence of two independently evolved vulture groups, Old World and New World vultures, provides a natural experiment in which to investigate convergent evolution due to obligate scavenging. We sequenced the genome of a cinereous vulture, and mapped it to the bald eagle reference genome, a close relative with a divergence time of 18 million years. By comparing the cinereous vulture to other avian genomes, we find positively selected genetic variations in this species associated with respiration, likely linked to their ability of immune defense responses and gastric acid secretion, consistent with their ability to digest carcasses. Comparisons between the Old World and New World vulture groups suggest convergent gene evolution. We assemble the cinereous vulture blood transcriptome from a second individual, and annotate genes. Finally, we infer the demographic history of the cinereous vulture which shows marked fluctuations in effective population size during the late Pleistocene. We present the first genome and transcriptome analyses of the cinereous vulture compared to other avian genomes and transcriptomes, revealing genetic signatures of dietary and environmental adaptations accompanied by possible convergent evolution between the Old World and New World vultures.

Convergent evolution of morphogenetic processes in fungi: Role of tetraspanins and NADPH oxidases 2 in plant pathogens and saprobes.

Science.gov (United States)

Malagnac, Fabienne; Bidard, Frédérique; Lalucque, Hervé; Brun, Sylvain; Lambou, Karine; Lebrun, Marc-Henri; Silar, Philippe

2008-01-01

Convergent evolution of trophic life style and morphological characters are very common in the fungal kingdom. Recently, we have shown that the same molecular machinery containing a tetraspanin and a NADPH oxidase has been recruited in two different fungal species for the same purpose (exiting from a melanized re-enforced cell at a focal weakened point), but at different stages of their development (ascospore germination and appressorium mediated penetration). Although this molecular machinery is required at these key developmental steps, it is also likely involved in specialized cellular functions at other stages of fungal development, as shown here for nutrient acquisition by Podospora anserina.

How IMS Enables Converged Services for Cable and 3G Technologies: A Survey

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Noël Crespi

2008-04-01

Full Text Available The IP multimedia subsystem (IMS is a service control overlay standardized by the 3GPP. The IMS is based on session initiation protocol (SIP to establish, modify, and terminate the sessions. It provides a clean separation between services, signaling, and media with the potential to enable control and management of services over multiple transport technologies. In the scope of fixed-mobile convergence, this paper is dedicated to presenting a review of how cable networks can be integrated into IMS technology to achieve 3G-cable horizontal convergence. Cable networks, as one of the major fixed broadband access technologies with PacketCable architecture, are able to provide broadband internet access and VoIP in addition to cable TV. In this article, we review the evolution in PacketCable architecture to take up IMS. In this way, we consider the standardization and research activities to address this integration. We review some important challenges such as SIP protocol compatibility, defining unique user profile, required enhancement in authentication process, QoS and charging system.

How IMS Enables Converged Services for Cable and 3G Technologies: A Survey

Directory of Open Access Journals (Sweden)

Mani Mehdi

2008-01-01

Full Text Available The IP multimedia subsystem (IMS is a service control overlay standardized by the 3GPP. The IMS is based on session initiation protocol (SIP to establish, modify, and terminate the sessions. It provides a clean separation between services, signaling, and media with the potential to enable control and management of services over multiple transport technologies. In the scope of fixed-mobile convergence, this paper is dedicated to presenting a review of how cable networks can be integrated into IMS technology to achieve 3G-cable horizontal convergence. Cable networks, as one of the major fixed broadband access technologies with PacketCable architecture, are able to provide broadband internet access and VoIP in addition to cable TV. In this article, we review the evolution in PacketCable architecture to take up IMS. In this way, we consider the standardization and research activities to address this integration. We review some important challenges such as SIP protocol compatibility, defining unique user profile, required enhancement in authentication process, QoS and charging system.

The evolution of jaw protrusion mechanics is tightly coupled to bentho-pelagic divergence in damselfishes (Pomacentridae).

Science.gov (United States)

Cooper, W James; Carter, Casey B; Conith, Andrew J; Rice, Aaron N; Westneat, Mark W

2017-02-15

Most species-rich lineages of aquatic organisms have undergone divergence between forms that feed from the substrate (benthic feeding) and forms that feed from the water column (pelagic feeding). Changes in trophic niche are frequently accompanied by changes in skull mechanics, and multiple fish lineages have evolved highly specialized biomechanical configurations that allow them to protrude their upper jaws toward the prey during feeding. Damselfishes (family Pomacentridae) are an example of a species-rich lineage with multiple trophic morphologies and feeding ecologies. We sought to determine whether bentho-pelagic divergence in the damselfishes is tightly coupled to changes in jaw protrusion ability. Using high-speed video recordings and kinematic analysis, we examined feeding performance in 10 species that include three examples of convergence on herbivory, three examples of convergence on omnivory and two examples of convergence on planktivory. We also utilized morphometrics to characterize the feeding morphology of an additional 40 species that represent all 29 damselfish genera. Comparative phylogenetic analyses were then used to examine the evolution of trophic morphology and biomechanical performance. We find that pelagic-feeding damselfishes (planktivores) are strongly differentiated from extensively benthic-feeding species (omnivores and herbivores) by their jaw protrusion ability, upper jaw morphology and the functional integration of upper jaw protrusion with lower jaw abduction. Most aspects of cranial form and function that separate these two ecological groups have evolved in correlation with each other and the evolution of the functional morphology of feeding in damselfishes has involved repeated convergence in form, function and ecology. © 2017. Published by The Company of Biologists Ltd.

A collaborative scheduling model for the supply-hub with multiple suppliers and multiple manufacturers.

Science.gov (United States)

Li, Guo; Lv, Fei; Guan, Xu

2014-01-01

This paper investigates a collaborative scheduling model in the assembly system, wherein multiple suppliers have to deliver their components to the multiple manufacturers under the operation of Supply-Hub. We first develop two different scenarios to examine the impact of Supply-Hub. One is that suppliers and manufacturers make their decisions separately, and the other is that the Supply-Hub makes joint decisions with collaborative scheduling. The results show that our scheduling model with the Supply-Hub is a NP-complete problem, therefore, we propose an auto-adapted differential evolution algorithm to solve this problem. Moreover, we illustrate that the performance of collaborative scheduling by the Supply-Hub is superior to separate decision made by each manufacturer and supplier. Furthermore, we also show that the algorithm proposed has good convergence and reliability, which can be applicable to more complicated supply chain environment.

Convergence of Romanian accounting regulations with IFRS. A longitudinal analysis

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Ioana PĂLĂRIE

2016-06-01

Full Text Available In this paper we analyse the evolution in the level of convergence of the Romanian accounting regulations with IFRS in the last decade. We focus our study on the accounting topics covered by IAS16, IAS17, IAS 41 and SIC15. We find that in 2005 the regulations exhibit a good level of convergence for property, plant and equipment, a medium level of convergence for lease accounting and divergence for accounting for the agricultural activity. The overall convergence level improved over time for all the topics analysed. These results indicate that the companies with dual reporting may incur lower costs in applying IFRS. Moreover, the national regulations offer the opportunity for a higher level of comparability in Romania of the financial statements prepared under IFRS with those prepared under national regulations. However, we underline that the institutional factors (such as the tax influence over accounting might negatively affect the convergence of practices.

Parallel selective pressures drive convergent diversification of phenotypes in pythons and boas.

Science.gov (United States)

Esquerré, Damien; Scott Keogh, J

2016-07-01

Pythons and boas are globally distributed and distantly related radiations with remarkable phenotypic and ecological diversity. We tested whether pythons, boas and their relatives have evolved convergent phenotypes when they display similar ecology. We collected geometric morphometric data on head shape for 1073 specimens representing over 80% of species. We show that these two groups display strong and widespread convergence when they occupy equivalent ecological niches and that the history of phenotypic evolution strongly matches the history of ecological diversification, suggesting that both processes are strongly coupled. These results are consistent with replicated adaptive radiation in both groups. We argue that strong selective pressures related to habitat-use have driven this convergence. Pythons and boas provide a new model system for the study of macro-evolutionary patterns of morphological and ecological evolution and they do so at a deeper level of divergence and global scale than any well-established adaptive radiation model systems. © 2016 John Wiley & Sons Ltd/CNRS.

Value Creation Through Integrated Networks and Convergence

Energy Technology Data Exchange (ETDEWEB)

De Martini, Paul; Taft, Jeffrey D.

2015-04-01

Customer adoption of distributed energy resources and public policies are driving changes in the uses of the distribution system. A system originally designed and built for one-way energy flows from central generating facilities to end-use customers is now experiencing injections of energy from customers anywhere on the grid and frequent reversals in the direction of energy flow. In response, regulators and utilities are re-thinking the design and operations of the grid to create more open and transactive electric networks. This evolution has the opportunity to unlock significant value for customers and utilities. Alternatively, failure to seize this potential may instead lead to an erosion of value if customers seek to defect and disconnect from the system. This paper will discuss how current grid modernization investments may be leveraged to create open networks that increase value through the interaction of intelligent devices on the grid and prosumerization of customers. Moreover, even greater value can be realized through the synergistic effects of convergence of multiple networks. This paper will highlight examples of the emerging nexus of non-electric networks with electricity.

Parallel or convergent evolution in human population genomic data revealed by genotype networks.

Science.gov (United States)

R Vahdati, Ali; Wagner, Andreas

2016-08-02

Genotype networks are representations of genetic variation data that are complementary to phylogenetic trees. A genotype network is a graph whose nodes are genotypes (DNA sequences) with the same broadly defined phenotype. Two nodes are connected if they differ in some minimal way, e.g., in a single nucleotide. We analyze human genome variation data from the 1,000 genomes project, and construct haploid genotype (haplotype) networks for 12,235 protein coding genes. The structure of these networks varies widely among genes, indicating different patterns of variation despite a shared evolutionary history. We focus on those genes whose genotype networks show many cycles, which can indicate homoplasy, i.e., parallel or convergent evolution, on the sequence level. For 42 genes, the observed number of cycles is so large that it cannot be explained by either chance homoplasy or recombination. When analyzing possible explanations, we discovered evidence for positive selection in 21 of these genes and, in addition, a potential role for constrained variation and purifying selection. Balancing selection plays at most a small role. The 42 genes with excess cycles are enriched in functions related to immunity and response to pathogens. Genotype networks are representations of genetic variation data that can help understand unusual patterns of genomic variation.

Evolution of 'smoke' induced seed germination in pyroendemic plants

Science.gov (United States)

Keeley, J. E.; Pausas, J.G.

2016-01-01

Pyroendemics are plants in which seedling germination and successful seedling recruitment are restricted to immediate postfire environments. In many fire-prone ecosystems species cue their germination to immediate postfire conditions. Here we address how species have evolved one very specific mechanism, which is using the signal of combustion products from biomass. This is often termed ‘smoke’ stimulated germination although it was first discovered in studies of charred wood effects on germination of species strictly tied to postfire conditions (pyroendemics). Smoke stimulated germination has been reported from a huge diversity of plant species. The fact that the organic compound karrikin (a product of the degradation of cellulose) is a powerful germination cue in many species has led to the assumption that this compound is the only chemical responsible for smoke-stimulated germination. Here we show that smoke-stimulated germination is a complex trait with different compounds involved. We propose that convergent evolution is a more parsimonious model for smoke stimulated germination, suggesting that this trait evolved multiple times in response to a variety of organic and inorganic chemical triggers in smoke. The convergent model is congruent with the evolution of many other fire-related traits.

Woodpeckers and Diamonds: Some Aspects of Evolutionary Convergence in Astrobiology.

Science.gov (United States)

Ćirković, Milan M

2018-05-01

Jared Diamond's argument against extraterrestrial intelligence from evolutionary contingency is subjected to critical scrutiny. As with the earlier arguments of George Gaylord Simpson, it contains critical loopholes that lead to its unraveling. From the point of view of the contemporary debates about biological evolution, perhaps the most contentious aspect of such arguments is their atemporal and gradualist usage of the space of all possible biological forms (morphospace). Such usage enables the translation of the adaptive value of a trait into the probability of its evolving. This procedure, it is argued, is dangerously misleading. Contra Diamond, there are reasons to believe that convergence not only plays an important role in the history of life, but also profoundly improves the prospects for search for extraterrestrial intelligence success. Some further considerations about the role of observation selection effects and our scaling of complexity in the great debate about contingency and convergence are given. Taken together, these considerations militate against the pessimism of Diamond's conclusion, and suggest that the search for traces and manifestations of extraterrestrial intelligences is far from forlorn. Key Words: Astrobiology-Evolution-Contingency-Convergence-Complex life-SETI-Major evolutionary transitions-Selection effects-Jared Diamond. Astrobiology 18, 491-502.

A Collaborative Scheduling Model for the Supply-Hub with Multiple Suppliers and Multiple Manufacturers

Directory of Open Access Journals (Sweden)

Guo Li

2014-01-01

Full Text Available This paper investigates a collaborative scheduling model in the assembly system, wherein multiple suppliers have to deliver their components to the multiple manufacturers under the operation of Supply-Hub. We first develop two different scenarios to examine the impact of Supply-Hub. One is that suppliers and manufacturers make their decisions separately, and the other is that the Supply-Hub makes joint decisions with collaborative scheduling. The results show that our scheduling model with the Supply-Hub is a NP-complete problem, therefore, we propose an auto-adapted differential evolution algorithm to solve this problem. Moreover, we illustrate that the performance of collaborative scheduling by the Supply-Hub is superior to separate decision made by each manufacturer and supplier. Furthermore, we also show that the algorithm proposed has good convergence and reliability, which can be applicable to more complicated supply chain environment.

A Collaborative Scheduling Model for the Supply-Hub with Multiple Suppliers and Multiple Manufacturers

Science.gov (United States)

Lv, Fei; Guan, Xu

2014-01-01

This paper investigates a collaborative scheduling model in the assembly system, wherein multiple suppliers have to deliver their components to the multiple manufacturers under the operation of Supply-Hub. We first develop two different scenarios to examine the impact of Supply-Hub. One is that suppliers and manufacturers make their decisions separately, and the other is that the Supply-Hub makes joint decisions with collaborative scheduling. The results show that our scheduling model with the Supply-Hub is a NP-complete problem, therefore, we propose an auto-adapted differential evolution algorithm to solve this problem. Moreover, we illustrate that the performance of collaborative scheduling by the Supply-Hub is superior to separate decision made by each manufacturer and supplier. Furthermore, we also show that the algorithm proposed has good convergence and reliability, which can be applicable to more complicated supply chain environment. PMID:24892104

Hybrid models for the simulation of microstructural evolution influenced by coupled, multiple physical processes

Energy Technology Data Exchange (ETDEWEB)

Tikare, Veena [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Hernandez-Rivera, Efrain [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Madison, Jonathan D. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Holm, Elizabeth Ann [Carnegie Mellon Univ., Pittsburgh, PA (United States); Patterson, Burton R. [Univ. of Florida, Gainesville, FL (United States). Dept. of Materials Science and Engineering; Homer, Eric R. [Brigham Young Univ., Provo, UT (United States). Dept. of Mechanical Engineering

2013-09-01

Most materials microstructural evolution processes progress with multiple processes occurring simultaneously. In this work, we have concentrated on the processes that are active in nuclear materials, in particular, nuclear fuels. These processes are coarsening, nucleation, differential diffusion, phase transformation, radiation-induced defect formation and swelling, often with temperature gradients present. All these couple and contribute to evolution that is unique to nuclear fuels and materials. Hybrid model that combines elements from the Potts Monte Carlo, phase-field models and others have been developed to address these multiple physical processes. These models are described and applied to several processes in this report. An important feature of the models developed are that they are coded as applications within SPPARKS, a Sandiadeveloped framework for simulation at the mesoscale of microstructural evolution processes by kinetic Monte Carlo methods. This makes these codes readily accessible and adaptable for future applications.

Pareto evolution of gene networks: an algorithm to optimize multiple fitness objectives

International Nuclear Information System (INIS)

Warmflash, Aryeh; Siggia, Eric D; Francois, Paul

2012-01-01

The computational evolution of gene networks functions like a forward genetic screen to generate, without preconceptions, all networks that can be assembled from a defined list of parts to implement a given function. Frequently networks are subject to multiple design criteria that cannot all be optimized simultaneously. To explore how these tradeoffs interact with evolution, we implement Pareto optimization in the context of gene network evolution. In response to a temporal pulse of a signal, we evolve networks whose output turns on slowly after the pulse begins, and shuts down rapidly when the pulse terminates. The best performing networks under our conditions do not fall into categories such as feed forward and negative feedback that also encode the input–output relation we used for selection. Pareto evolution can more efficiently search the space of networks than optimization based on a single ad hoc combination of the design criteria. (paper)

Pareto evolution of gene networks: an algorithm to optimize multiple fitness objectives.

Science.gov (United States)

Warmflash, Aryeh; Francois, Paul; Siggia, Eric D

2012-10-01

The computational evolution of gene networks functions like a forward genetic screen to generate, without preconceptions, all networks that can be assembled from a defined list of parts to implement a given function. Frequently networks are subject to multiple design criteria that cannot all be optimized simultaneously. To explore how these tradeoffs interact with evolution, we implement Pareto optimization in the context of gene network evolution. In response to a temporal pulse of a signal, we evolve networks whose output turns on slowly after the pulse begins, and shuts down rapidly when the pulse terminates. The best performing networks under our conditions do not fall into categories such as feed forward and negative feedback that also encode the input-output relation we used for selection. Pareto evolution can more efficiently search the space of networks than optimization based on a single ad hoc combination of the design criteria.

Specificity and multiplicity in the recognition of individuals: implications for the evolution of social behaviour.

Science.gov (United States)

Wiley, R H

2013-02-01

Recognition of conspecifics occurs when individuals classify sets of conspecifics based on sensory input from them and associate these sets with different responses. Classification of conspecifics can vary in specificity (the number of individuals included in a set) and multiplicity (the number of sets differentiated). In other words, the information transmitted varies in complexity. Although recognition of conspecifics has been reported in a wide variety of organisms, few reports have addressed the specificity or multiplicity of this capability. This review discusses examples of these patterns, the mechanisms that can produce them, and the evolution of these mechanisms. Individual recognition is one end of a spectrum of specificity, and binary classification of conspecifics is one end of a spectrum of multiplicity. In some cases, recognition requires no more than simple forms of learning, such as habituation, yet results in individually specific recognition. In other cases, recognition of individuals involves complex associations of multiple cues with multiple previous experiences in particular contexts. Complex mechanisms for recognition are expected to evolve only when simpler mechanisms do not provide sufficient specificity and multiplicity to obtain the available advantages. In particular, the evolution of cooperation and deception is always promoted by specificity and multiplicity in recognition. Nevertheless, there is only one demonstration that recognition of specific individuals contributes to cooperation in animals other than primates. Human capacities for individual recognition probably have a central role in the evolution of complex forms of human cooperation and deception. Although relatively little studied, this capability probably rivals cognitive abilities for language. © 2012 The Author. Biological Reviews © 2012 Cambridge Philosophical Society.

Can evolutionary convergence be tested on Europa?

Energy Technology Data Exchange (ETDEWEB)

Chela-Flores, Julian [Instituto de Estudios Avanzados, Caracas (Venezuela); [Abdus Salam International Centre for Theoretical Physics, Trieste (Italy)]. E-mail: chelaf@ictp.trieste.it

2002-09-01

A major objective in solar system exploration has to be the insertion of appropriate biology-oriented experiments in future missions. We discuss various reasons for suggesting that this type of research be considered a high priority for feasibility studies and, subsequently, for technological development of appropriate melters and submersibles. With the assumption that Darwin's theory is valid for the evolution of life anywhere in the universe, various degrees of convergent phenomena argue in favor of the conjecture that universal evolution of intelligent behavior is just a matter of time and preservation of steady planetary conditions. A preliminary test of this conjecture is feasible with experiments involving evolutionary biosignatures on Europa. (author)

Biomarkers in the evolution of multiple sclerosis.

Science.gov (United States)

Berger, Thomas

2017-11-01

Nonimaging biomarkers can be applied in differential diagnosis, evaluation of disease progression and therapy monitoring of multiple sclerosis (MS). Presence of oligoclonal IgG bands in cerebrospinal fluid is a diagnostic element and a negative predictor of MS evolution. AQP4 antibodies are pathogenic and diagnostic for neuromyelitis optica spectrum disorder. Antibodies to myelin oligodendrocyte glycoprotein develop in about 50% of predominantly pediatric patients with acute disseminated encephalomyelitis, but their possible role in pathogenesis is unknown. Currently, there are no individualized biomarkers suitable to track disease progression. Neutralizing antibodies against IFN-β, natalizumab and daclizumab arise with variable frequency and reduce treatment efficacy. The anti-John Cunningham virus antibody index has potential as a biomarker for risk of progressive multifocal leukoencephalopathy.

Reacquisition of the lower temporal bar in sexually dimorphic fossil lizards provides a rare case of convergent evolution.

Science.gov (United States)

Simões, Tiago R; Funston, Gregory F; Vafaeian, Behzad; Nydam, Randall L; Doschak, Michael R; Caldwell, Michael W

2016-04-13

Temporal fenestration has long been considered a key character to understand relationships amongst reptiles. In particular, the absence of the lower temporal bar (LTB) is considered one of the defining features of squamates (lizards and snakes). In a re-assessment of the borioteiioid lizard Polyglyphanodon sternbergi (Cretaceous, North America), we detected a heretofore unrecognized ontogenetic series, sexual dimorphism (a rare instance for Mesozoic reptiles), and a complete LTB, a feature only recently recognized for another borioteiioid, Tianyusaurus zhengi (Cretaceous, China). A new phylogenetic analysis (with updates on a quarter of the scorings for P. sternbergi) indicates not only that the LTB was reacquired in squamates, but it happened independently at least twice. An analysis of the functional significance of the LTB using proxies indicates that, unlike for T. zhengi, this structure had no apparent functional advantage in P. sternbergi, and it is better explained as the result of structural constraint release. The observed canalization against a LTB in squamates was broken at some point in the evolution of borioteiioids, whereas never re-occuring in other squamate lineages. This case of convergent evolution involves a mix of both adaptationist and structuralist causes, which is unusual for both living and extinct vertebrates.

Reacquisition of the lower temporal bar in sexually dimorphic fossil lizards provides a rare case of convergent evolution

Science.gov (United States)

Simões, Tiago R.; Funston, Gregory F.; Vafaeian, Behzad; Nydam, Randall L.; Doschak, Michael R.; Caldwell, Michael W.

2016-04-01

Temporal fenestration has long been considered a key character to understand relationships amongst reptiles. In particular, the absence of the lower temporal bar (LTB) is considered one of the defining features of squamates (lizards and snakes). In a re-assessment of the borioteiioid lizard Polyglyphanodon sternbergi (Cretaceous, North America), we detected a heretofore unrecognized ontogenetic series, sexual dimorphism (a rare instance for Mesozoic reptiles), and a complete LTB, a feature only recently recognized for another borioteiioid, Tianyusaurus zhengi (Cretaceous, China). A new phylogenetic analysis (with updates on a quarter of the scorings for P. sternbergi) indicates not only that the LTB was reacquired in squamates, but it happened independently at least twice. An analysis of the functional significance of the LTB using proxies indicates that, unlike for T. zhengi, this structure had no apparent functional advantage in P. sternbergi, and it is better explained as the result of structural constraint release. The observed canalization against a LTB in squamates was broken at some point in the evolution of borioteiioids, whereas never re-occuring in other squamate lineages. This case of convergent evolution involves a mix of both adaptationist and structuralist causes, which is unusual for both living and extinct vertebrates.

BUILD-UP OF UNDERSTANDING OF TECHNOLOGICAL CONVERGENCE: EVIDENCE FROM PRINTED INTELLIGENCE INDUSTRY

OpenAIRE

MATTI KARVONEN; MATTI LEHTOVAARA; TUOMO KÄSSI

2012-01-01

The purpose of the paper is to analyze the dynamics between traditional and emerging new industries in converging industry environments. The paper identifies different convergence types and utilizes the framework to analyze the evolution of printed intelligence and RFID markets. The primary source of information is based on the main RFID industry players, patents, and 12 semistructured interviews conducted by the research group. The results reveal that the emerging industry is in the early st...

Convergence of scalar-tensor theories towards general relativity and primordial nucleosynthesis

International Nuclear Information System (INIS)

Serna, A; Alimi, J-M; Navarro, A

2002-01-01

In this paper, we analyse the conditions for convergence towards general relativity of scalar-tensor gravity theories defined by an arbitrary coupling function α (in the Einstein frame). We show that, in general, the evolution of the scalar field (φ) is governed by two opposite mechanisms: an attraction mechanism which tends to drive scalar-tensor models towards Einstein's theory, and a repulsion mechanism which has the contrary effect. The attraction mechanism dominates the recent epochs of the universe evolution if, and only if, the scalar field and its derivative satisfy certain boundary conditions. Since these conditions for convergence towards general relativity depend on the particular scalar-tensor theory used to describe the universe evolution, the nucleosynthesis bounds on the present value of the coupling function, α 0 , strongly differ from some theories to others. For example, in theories defined by α ∝ |φ| analytical estimates lead to very stringent nucleosynthesis bounds on α 0 (∼ -19 ). By contrast, in scalar-tensor theories defined by α ∝ φ much larger limits on α 0 (∼ -7 ) are found

Management Control in Major Brazilian Multiple Banks: the Impact of Internationalization and Convergence of Accounting Standards on the Control Systems

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João Carlos Damasceno Reis

2014-08-01

Full Text Available This study verifies the impact caused by the processes of globalization and convergence to international accounting standards on the managerial control systems of the largest multiple banks that operate in Brazil. The study was exploratory in nature, with the use of the case study method and the application of questionnaires containing mostly open questions to upper tier executives of four major Brazilian banks. The analysis showed that globalization has resulted in improved control systems and widespread use of information technology. It was also found that the convergence to international accounting standards occurred properly, thanks to the steps taken by the Central Bank that aimed at an agile updating of the Brazilian accounting standards laid down for banks operating in Brazil, in line with international standards. In general, the researched banks did not report a significant impact of convergence to the IFRS on their management control systems; adherence to the international accounting standards has had more significant impacts on information systems, especially regarding the new reporting and transparency standards, rather than on management controls. This result signals that the management control systems of the four banks in the sample are in line with Anthony (1965’s vision, that is, that flexibility to adapt to every change in the external environment might actually increase risks of failure.

Fiber-wireless convergence in next-generation communication networks systems, architectures, and management

CERN Document Server

Chang, Gee-Kung; Ellinas, Georgios

2017-01-01

This book investigates new enabling technologies for Fi-Wi convergence. The editors discuss Fi-Wi technologies at the three major network levels involved in the path towards convergence: system level, network architecture level, and network management level. The main topics will be: a. At system level: Radio over Fiber (digitalized vs. analogic, standardization, E-band and beyond) and 5G wireless technologies; b. Network architecture level: NGPON, WDM-PON, BBU Hotelling, Cloud Radio Access Networks (C-RANs), HetNets. c. Network management level: SDN for convergence, Next-generation Point-of-Presence, Wi-Fi LTE Handover, Cooperative MultiPoint. • Addresses the Fi-Wi convergence issues at three different levels, namely at the system level, network architecture level, and network management level • Provides approaches in communication systems, network architecture, and management that are expected to steer the evolution towards fiber-wireless convergence • Contributions from leading experts in the field of...

Mosco convergence of integral functionals and its applications

International Nuclear Information System (INIS)

Tolstonogov, Aleksandr A

2009-01-01

Questions relating to the Mosco convergence of integral functionals defined on the space of square integrable functions taking values in a Hilbert space are investigated. The integrands of these functionals are time-dependent proper, convex, lower semicontinuous functions on the Hilbert space. The results obtained are applied to the analysis of the dependence on the parameter of solutions of evolution equations involving time-dependent subdifferential operators. For example a parabolic inclusion is considered, where the right-hand side contains a sum of the p-Laplacian and the subdifferential of the indicator function of a time-dependent closed convex set. The convergence as p→+∞ of solutions of this inclusion is investigated. Bibliography: 20 titles.

Convergence Science in a Nano World

Science.gov (United States)

Cady, Nathaniel

2013-01-01

Convergence is a new paradigm that brings together critical advances in the life sciences, physical sciences and engineering. Going beyond traditional “interdisciplinary” studies, “convergence” describes the culmination of truly integrated research and development, yielding revolutionary advances in both scientific research and new technologies. At its core, nanotechnology embodies these elements of convergence science by bringing together multiple disciplines with the goal of creating innovative and groundbreaking technologies. In the biological and biomedical sciences, nanotechnology research has resulted in dramatic improvements in sensors, diagnostics, imaging, and even therapeutics. In particular, there is a current push to examine the interface between the biological world and micro/nano-scale systems. For example, my laboratory is developing novel strategies for spatial patterning of biomolecules, electrical and optical biosensing, nanomaterial delivery systems, cellular patterning techniques, and the study of cellular interactions with nano-structured surfaces. In this seminar, I will give examples of how convergent research is being applied to three major areas of biological research &endash; cancer diagnostics, microbiology, and DNA-based biosensing. These topics will be presented as case studies, showing the benefits (and challenges) of multi-disciplinary, convergent research and development.

Convergent Metabolic Specialization through Distinct Evolutionary Paths in Pseudomonas aeruginosa.

Science.gov (United States)

La Rosa, Ruggero; Johansen, Helle Krogh; Molin, Søren

2018-04-10

Evolution by natural selection under complex and dynamic environmental conditions occurs through intricate and often counterintuitive trajectories affecting many genes and metabolic solutions. To study short- and long-term evolution of bacteria in vivo , we used the natural model system of cystic fibrosis (CF) infection. In this work, we investigated how and through which trajectories evolution of Pseudomonas aeruginosa occurs when migrating from the environment to the airways of CF patients, and specifically, we determined reduction of growth rate and metabolic specialization as signatures of adaptive evolution. We show that central metabolic pathways of three distinct Pseudomonas aeruginosa lineages coevolving within the same environment become restructured at the cost of versatility during long-term colonization. Cell physiology changes from naive to adapted phenotypes resulted in (i) alteration of growth potential that particularly converged to a slow-growth phenotype, (ii) alteration of nutritional requirements due to auxotrophy, (iii) tailored preference for carbon source assimilation from CF sputum, (iv) reduced arginine and pyruvate fermentation processes, and (v) increased oxygen requirements. Interestingly, although convergence was evidenced at the phenotypic level of metabolic specialization, comparative genomics disclosed diverse mutational patterns underlying the different evolutionary trajectories. Therefore, distinct combinations of genetic and regulatory changes converge to common metabolic adaptive trajectories leading to within-host metabolic specialization. This study gives new insight into bacterial metabolic evolution during long-term colonization of a new environmental niche. IMPORTANCE Only a few examples of real-time evolutionary investigations in environments outside the laboratory are described in the scientific literature. Remembering that biological evolution, as it has progressed in nature, has not taken place in test tubes, it is not

DOES THE MAASTRICHT CONVERGENCE CRITERIA WORK?

Directory of Open Access Journals (Sweden)

Karsai Zoltán-Krisztián

2012-12-01

Full Text Available During its 13 year history, the euro area experienced the most severe economic downturn in the late 2000s as a result of the 2007 financial-economic crisis stemming from the US banking sector. The crisis in the monetary union, besides posting a significant economic and social cost, revealed several weaknesses not just of the currency block as a whole, but also of its constituting members, which were masked by the prosperous economic environment characteristic for the 2000s. These conditions have put to the test the solidarity among the euro zone members, or in other words the existence of the currency block. One important problem of the currency block is the lack of harmony between the fiscal and economic policies of the member states, creating several and occasionally very divergent parts of the currency block. The aim of this research is to enhance the Maastricht convergence criteria’s and the Stability and Growth Pact’s role as a monitoring mechanism, allowing them to become more informative tools for the policy makers. For this, based on the relevant literature, we propose new potential explanatory variables which could enhance the role of the Maastricht convergence criteria and the Stability and Growth Pact. Some of the studied variables, like indebtedness of the private sector, capital flow compared to the size of the economy, government revenue compared to total public debt and current account balance help in enforcing the nominal convergence, while others (real labour productivity contribute to the real convergence. The explanatory power of the proposed variables are investigated in the case of France, Germany, Greece, Ireland, Italy, Portugal and Spain for the period comprised between 2000Q1-2011Q4. Results of the research show that with the exception of government revenue compared to total public debt, all proposed variables have significant explanatory power regarding the evolution of the state of the economy in all

Genome profiling of sterol synthesis shows convergent evolution in parasites and guides chemotherapeutic attack.

Science.gov (United States)

Fügi, Matthias A; Gunasekera, Kapila; Ochsenreiter, Torsten; Guan, Xueli; Wenk, Markus R; Mäser, Pascal

2014-05-01

Sterols are an essential class of lipids in eukaryotes, where they serve as structural components of membranes and play important roles as signaling molecules. Sterols are also of high pharmacological significance: cholesterol-lowering drugs are blockbusters in human health, and inhibitors of ergosterol biosynthesis are widely used as antifungals. Inhibitors of ergosterol synthesis are also being developed for Chagas's disease, caused by Trypanosoma cruzi. Here we develop an in silico pipeline to globally evaluate sterol metabolism and perform comparative genomics. We generate a library of hidden Markov model-based profiles for 42 sterol biosynthetic enzymes, which allows expressing the genomic makeup of a given species as a numerical vector. Hierarchical clustering of these vectors functionally groups eukaryote proteomes and reveals convergent evolution, in particular metabolic reduction in obligate endoparasites. We experimentally explore sterol metabolism by testing a set of sterol biosynthesis inhibitors against trypanosomatids, Plasmodium falciparum, Giardia, and mammalian cells, and by quantifying the expression levels of sterol biosynthetic genes during the different life stages of T. cruzi and Trypanosoma brucei. The phenotypic data correlate with genomic makeup for simvastatin, which showed activity against trypanosomatids. Other findings, such as the activity of terbinafine against Giardia, are not in agreement with the genotypic profile.

Cultural transmission results in convergence towards colour term universals

Science.gov (United States)

Xu, Jing; Dowman, Mike; Griffiths, Thomas L.

2013-01-01

As in biological evolution, multiple forces are involved in cultural evolution. One force is analogous to selection, and acts on differences in the fitness of aspects of culture by influencing who people choose to learn from. Another force is analogous to mutation, and influences how culture changes over time owing to errors in learning and the effects of cognitive biases. Which of these forces need to be appealed to in explaining any particular aspect of human cultures is an open question. We present a study that explores this question empirically, examining the role that the cognitive biases that influence cultural transmission might play in universals of colour naming. In a large-scale laboratory experiment, participants were shown labelled examples from novel artificial systems of colour terms and were asked to classify other colours on the basis of those examples. The responses of each participant were used to generate the examples seen by subsequent participants. By simulating cultural transmission in the laboratory, we were able to isolate a single evolutionary force—the effects of cognitive biases, analogous to mutation—and examine its consequences. Our results show that this process produces convergence towards systems of colour terms similar to those seen across human languages, providing support for the conclusion that the effects of cognitive biases, brought out through cultural transmission, can account for universals in colour naming. PMID:23486436

Drug-Driven Phenotypic Convergence Supports Rational Treatment Strategies of Chronic Infections

DEFF Research Database (Denmark)

Imamovic, Lejla; Ellabaan, Mostafa Mostafa Hashim; Dantas Machado, Ana Manuel

2018-01-01

Chronic Pseudomonas aeruginosa infections evade antibiotic therapy and are associated with mortality in cystic fibrosis (CF) patients. We find that in vitro resistance evolution of P. aeruginosa toward clinically relevant antibiotics leads to phenotypic convergence toward distinct states. These s...

Trophic divergence despite morphological convergence in a continental radiation of snakes.

Science.gov (United States)

Grundler, Michael C; Rabosky, Daniel L

2014-07-22

Ecological and phenotypic convergence is a potential outcome of adaptive radiation in response to ecological opportunity. However, a number of factors may limit convergence during evolutionary radiations, including interregional differences in biogeographic history and clade-specific constraints on form and function. Here, we demonstrate that a single clade of terrestrial snakes from Australia--the oxyuranine elapids--exhibits widespread morphological convergence with a phylogenetically diverse and distantly related assemblage of snakes from North America. Australian elapids have evolved nearly the full spectrum of phenotypic modalities that occurs among North American snakes. Much of the convergence appears to involve the recurrent evolution of stereotyped morphologies associated with foraging mode, locomotion and habitat use. By contrast, analysis of snake diets indicates striking divergence in feeding ecology between these faunas, partially reflecting regional differences in ecological allometry between Australia and North America. Widespread phenotypic convergence with the North American snake fauna coupled with divergence in feeding ecology are clear examples of how independent continental radiations may converge along some ecological axes yet differ profoundly along others. © 2014 The Author(s) Published by the Royal Society. All rights reserved.

Convergence accommodation to convergence CA/C ratio: convergence versus divergence.

Science.gov (United States)

Simmons, Joshua M; Firth, Alison Y

2014-09-01

To determine whether the convergence accommodation to convergence (CA/C) ratio during divergence with base-in (BI) prisms is of a similar or different magnitude to that measured during convergence with base-out (BO) prisms. Eighteen participants with normal binocular single vision were recruited. The participants viewed a pseudo-Gaussian target, which consisted of a light emitting diode (LED) behind a diffusing screen at 40 cm. After 5 minutes of dark adaptation, the refractive status of the eye was measured without any prism using a Shin-Nippon SRW-5000 autorefractor. The participant held the selected prism (5Δ or 10Δ BO or BI, counterbalanced) in front of their right eye and obtained a single, fused image of the target while refractive measures were taken with each. A 30-second rest period was given between measurements. The mean age of the participants was 20.6±3.22 years. The mean CA/C ratios for the 5Δ BO, 10Δ BO, 5Δ BI, and 10Δ BI were 0.108 (±0.074) D/Δ, 0.110 (±0.056) D/Δ, 0.100 (±0.090) D/Δ, and 0.089 (±0.055) D/Δ, respectively. A 2-factor repeated measures ANOVA found that the CA/C ratio did not significantly change with differing levels of prism-induced convergence and divergence (p=0.649). Change in accommodation induced by manipulating vergence is similar whether convergence or divergence are induced. The CA/C ratio did not show any change with differing levels of prism-induced convergence and divergence.

Testing Adaptive Hypotheses of Convergence with Functional Landscapes: A Case Study of Bone-Cracking Hypercarnivores

Science.gov (United States)

Tseng, Zhijie Jack

2013-01-01

Morphological convergence is a well documented phenomenon in mammals, and adaptive explanations are commonly employed to infer similar functions for convergent characteristics. I present a study that adopts aspects of theoretical morphology and engineering optimization to test hypotheses about adaptive convergent evolution. Bone-cracking ecomorphologies in Carnivora were used as a case study. Previous research has shown that skull deepening and widening are major evolutionary patterns in convergent bone-cracking canids and hyaenids. A simple two-dimensional design space, with skull width-to-length and depth-to-length ratios as variables, was used to examine optimized shapes for two functional properties: mechanical advantage (MA) and strain energy (SE). Functionality of theoretical skull shapes was studied using finite element analysis (FEA) and visualized as functional landscapes. The distribution of actual skull shapes in the landscape showed a convergent trend of plesiomorphically low-MA and moderate-SE skulls evolving towards higher-MA and moderate-SE skulls; this is corroborated by FEA of 13 actual specimens. Nevertheless, regions exist in the landscape where high-MA and lower-SE shapes are not represented by existing species; their vacancy is observed even at higher taxonomic levels. Results highlight the interaction of biomechanical and non-biomechanical factors in constraining general skull dimensions to localized functional optima through evolution. PMID:23734244

Testing adaptive hypotheses of convergence with functional landscapes: a case study of bone-cracking hypercarnivores.

Directory of Open Access Journals (Sweden)

Zhijie Jack Tseng

Full Text Available Morphological convergence is a well documented phenomenon in mammals, and adaptive explanations are commonly employed to infer similar functions for convergent characteristics. I present a study that adopts aspects of theoretical morphology and engineering optimization to test hypotheses about adaptive convergent evolution. Bone-cracking ecomorphologies in Carnivora were used as a case study. Previous research has shown that skull deepening and widening are major evolutionary patterns in convergent bone-cracking canids and hyaenids. A simple two-dimensional design space, with skull width-to-length and depth-to-length ratios as variables, was used to examine optimized shapes for two functional properties: mechanical advantage (MA and strain energy (SE. Functionality of theoretical skull shapes was studied using finite element analysis (FEA and visualized as functional landscapes. The distribution of actual skull shapes in the landscape showed a convergent trend of plesiomorphically low-MA and moderate-SE skulls evolving towards higher-MA and moderate-SE skulls; this is corroborated by FEA of 13 actual specimens. Nevertheless, regions exist in the landscape where high-MA and lower-SE shapes are not represented by existing species; their vacancy is observed even at higher taxonomic levels. Results highlight the interaction of biomechanical and non-biomechanical factors in constraining general skull dimensions to localized functional optima through evolution.

Right-handed snakes: convergent evolution of asymmetry for functional specialization

OpenAIRE

Hoso, Masaki; Asami, Takahiro; Hori, Michio

2007-01-01

External asymmetry found in diverse animals bears critical functions to fulfil ecological requirements. Some snail-eating arthropods exhibit directional asymmetry in their feeding apparatus for foraging efficiency because dextral (clockwise) species are overwhelmingly predominant in snails. Here, we show convergence of directional asymmetry in the dentition of snail-eating vertebrates. We found that snakes in the subfamily Pareatinae, except for non-snail-eating specialists, have more teeth o...

Single- and Multiple-Objective Optimization with Differential Evolution and Neural Networks

Science.gov (United States)

Rai, Man Mohan

2006-01-01

Genetic and evolutionary algorithms have been applied to solve numerous problems in engineering design where they have been used primarily as optimization procedures. These methods have an advantage over conventional gradient-based search procedures became they are capable of finding global optima of multi-modal functions and searching design spaces with disjoint feasible regions. They are also robust in the presence of noisy data. Another desirable feature of these methods is that they can efficiently use distributed and parallel computing resources since multiple function evaluations (flow simulations in aerodynamics design) can be performed simultaneously and independently on ultiple processors. For these reasons genetic and evolutionary algorithms are being used more frequently in design optimization. Examples include airfoil and wing design and compressor and turbine airfoil design. They are also finding increasing use in multiple-objective and multidisciplinary optimization. This lecture will focus on an evolutionary method that is a relatively new member to the general class of evolutionary methods called differential evolution (DE). This method is easy to use and program and it requires relatively few user-specified constants. These constants are easily determined for a wide class of problems. Fine-tuning the constants will off course yield the solution to the optimization problem at hand more rapidly. DE can be efficiently implemented on parallel computers and can be used for continuous, discrete and mixed discrete/continuous optimization problems. It does not require the objective function to be continuous and is noise tolerant. DE and applications to single and multiple-objective optimization will be included in the presentation and lecture notes. A method for aerodynamic design optimization that is based on neural networks will also be included as a part of this lecture. The method offers advantages over traditional optimization methods. It is more

Occurrence and prognostic significance of cytogenetic evolution in patients with multiple myeloma

Science.gov (United States)

Binder, M; Rajkumar, S V; Ketterling, R P; Dispenzieri, A; Lacy, M Q; Gertz, M A; Buadi, F K; Hayman, S R; Hwa, Y L; Zeldenrust, S R; Lust, J A; Russell, S J; Leung, N; Kapoor, P; Go, R S; Gonsalves, W I; Kyle, R A; Kumar, S K

2016-01-01

Cytogenetic evaluation at the time of diagnosis is essential for risk stratification in multiple myeloma, however little is known about the occurrence and prognostic significance of cytogenetic evolution during follow-up. We studied 989 patients with multiple myeloma, including 304 patients with at least two cytogenetic evaluations. Multivariable-adjusted regression models were used to assess the associations between the parameters of interest and cytogenetic evolution as well as overall survival. The prognostic significance of baseline cytogenetic abnormalities was most pronounced at the time of diagnosis and attenuated over time. In the patients with serial cytogenetic evaluations, the presence of t(11;14) at the time of diagnosis was associated with decreased odds of cytogenetic evolution during follow-up (odds ratio (OR)=0.22, 95% confidence interval (CI)=0.09–0.56, P=0.001), while the presence of at least one trisomy or tetrasomy was associated with increased odds (OR=2.96, 95% CI=1.37–6.42, P=0.006). The development of additional abnormalities during the 3 years following diagnosis was associated with increased subsequent mortality (hazard ratio=3.31, 95% CI=1.73–6.30, P<0.001). These findings emphasize the importance of the underlying clonal disease process for risk assessment and suggest that selected patients may benefit from repeated risk stratification. PMID:26967818

Convergent evolution of vascular optimization in kelp (Laminariales)

DEFF Research Database (Denmark)

Drobnitch, Sarah Tepler; Jensen, Kaare Hartvig; Prentice, Paige

2015-01-01

Terrestrial plants and mammals, although separated by a great evolutionary distance, have each arrived at a highly conserved body plan in which universal allometric scaling relationships govern the anatomy of vascular networks and key functional metabolic traits. The universality of allometric...... (Phaeophyceae) are one such group—as distantly related to plants as mammals, they have convergently evolved a plant-like body plan and a specialized phloem-like transport network. To evaluate possible scaling and optimization in the kelp vascular system, we developed a model of optimized transport anatomy...... and tested it with measurements of the giant kelp, Macrocystis pyrifera, which is among the largest and most successful of macroalgae. We also evaluated three classical allometric relationships pertaining to plant vascular tissues with a diverse sampling of kelp species. Macrocystis pyrifera displays strong...

The Cellular Differential Evolution Based on Chaotic Local Search

Directory of Open Access Journals (Sweden)

Qingfeng Ding

2015-01-01

Full Text Available To avoid immature convergence and tune the selection pressure in the differential evolution (DE algorithm, a new differential evolution algorithm based on cellular automata and chaotic local search (CLS or ccDE is proposed. To balance the exploration and exploitation tradeoff of differential evolution, the interaction among individuals is limited in cellular neighbors instead of controlling parameters in the canonical DE. To improve the optimizing performance of DE, the CLS helps by exploring a large region to avoid immature convergence in the early evolutionary stage and exploiting a small region to refine the final solutions in the later evolutionary stage. What is more, to improve the convergence characteristics and maintain the population diversity, the binomial crossover operator in the canonical DE may be instead by the orthogonal crossover operator without crossover rate. The performance of ccDE is widely evaluated on a set of 14 bound constrained numerical optimization problems compared with the canonical DE and several DE variants. The simulation results show that ccDE has better performances in terms of convergence rate and solution accuracy than other optimizers.

FireProt: Energy- and Evolution-Based Computational Design of Thermostable Multiple-Point Mutants.

Science.gov (United States)

Bednar, David; Beerens, Koen; Sebestova, Eva; Bendl, Jaroslav; Khare, Sagar; Chaloupkova, Radka; Prokop, Zbynek; Brezovsky, Jan; Baker, David; Damborsky, Jiri

2015-11-01

There is great interest in increasing proteins' stability to enhance their utility as biocatalysts, therapeutics, diagnostics and nanomaterials. Directed evolution is a powerful, but experimentally strenuous approach. Computational methods offer attractive alternatives. However, due to the limited reliability of predictions and potentially antagonistic effects of substitutions, only single-point mutations are usually predicted in silico, experimentally verified and then recombined in multiple-point mutants. Thus, substantial screening is still required. Here we present FireProt, a robust computational strategy for predicting highly stable multiple-point mutants that combines energy- and evolution-based approaches with smart filtering to identify additive stabilizing mutations. FireProt's reliability and applicability was demonstrated by validating its predictions against 656 mutations from the ProTherm database. We demonstrate that thermostability of the model enzymes haloalkane dehalogenase DhaA and γ-hexachlorocyclohexane dehydrochlorinase LinA can be substantially increased (ΔTm = 24°C and 21°C) by constructing and characterizing only a handful of multiple-point mutants. FireProt can be applied to any protein for which a tertiary structure and homologous sequences are available, and will facilitate the rapid development of robust proteins for biomedical and biotechnological applications.

FireProt: Energy- and Evolution-Based Computational Design of Thermostable Multiple-Point Mutants.

Directory of Open Access Journals (Sweden)

David Bednar

2015-11-01

Full Text Available There is great interest in increasing proteins' stability to enhance their utility as biocatalysts, therapeutics, diagnostics and nanomaterials. Directed evolution is a powerful, but experimentally strenuous approach. Computational methods offer attractive alternatives. However, due to the limited reliability of predictions and potentially antagonistic effects of substitutions, only single-point mutations are usually predicted in silico, experimentally verified and then recombined in multiple-point mutants. Thus, substantial screening is still required. Here we present FireProt, a robust computational strategy for predicting highly stable multiple-point mutants that combines energy- and evolution-based approaches with smart filtering to identify additive stabilizing mutations. FireProt's reliability and applicability was demonstrated by validating its predictions against 656 mutations from the ProTherm database. We demonstrate that thermostability of the model enzymes haloalkane dehalogenase DhaA and γ-hexachlorocyclohexane dehydrochlorinase LinA can be substantially increased (ΔTm = 24°C and 21°C by constructing and characterizing only a handful of multiple-point mutants. FireProt can be applied to any protein for which a tertiary structure and homologous sequences are available, and will facilitate the rapid development of robust proteins for biomedical and biotechnological applications.

The anticipation of converging industries a concept applied to nutraceuticals and functional foods

CERN Document Server

Curran, Clive-Steven

2013-01-01

The blurring of boundaries between hitherto distinct scientific disciplines, technologies or markets is a common and powerful phenomenon. Subjects of this convergence often change consumer behaviours, favouring products and platforms with multiple functions. The Anticipation of Converging Industries provides a detailed focus on the triggers, drivers and consequences of convergence to create a more concise definition of convergence.   This detailed analysis includes a specifically developed toolbox for ‘convergence foresight’, creating a forecasting method for convergence trends. With the focus on the chemical, biotechnological and pharmaceutical industries, several indicators of convergence in the areas of Nutraceuticals/Functional Foods, Cosmeceuticals and ICT are derived from samples including over 1million patents and scientific publications.   By supporting this methodical approach with real world data, The Anticipation of Converging Industries is perfect for industry practitioners looking for a com...

Existence and convergence theorems for evolutionary hemivariational inequalities of second order

Directory of Open Access Journals (Sweden)

Zijia Peng

2015-03-01

Full Text Available This article concerns with a class of evolutionary hemivariational inequalities in the framework of evolution triple. Based on the Rothe method, monotonicity-compactness technique and the properties of Clarke's generalized derivative and gradient, the existence and convergence theorems to these problems are established. The main idea in the proof is using the time difference to construct the approximate problems. The work generalizes the existence results on evolution inclusions and hemivariational inequalities of second order.

Demographic Evolution in Romania – Convergence or Peripherisation?

Directory of Open Access Journals (Sweden)

Adriana Veronica Litra

2006-02-01

Full Text Available Romania began its demographic transition about one century later than the developed countries. We put the blame of this gap on the delayed economic, social and political development in comparison with the Western Europe. But also, it could not be forgotten the shift from a population forced and subdue by the totalitary regime, to a free people to decide when to have a child or how large should be the family. During transition, Romania has pointed many negative demographic evolutions, as compared with the other european countries. It may be said that the transition in Romania over the period 1990-2004 adjusted the classical pattern of demographic evolution. Not fully felt at this moment, we will probably find ourselves few decades later older, less, deprived of skilled labor force and unbalanced as gender ratio.

Convergence of scalar-tensor theories towards general relativity and primordial nucleosynthesis

Energy Technology Data Exchange (ETDEWEB)

Serna, A [Dept. Fisica y Computacion, Universidad Miguel Hernandez, E03202-Elche (Spain); Alimi, J-M [LAEC, CNRS-UMR 8631, Observatoire de Paris-Meudon, F92195-Meudon (France); Navarro, A [Dept. Fisica, Universidad de Murcia, E30071-Murcia (Spain)

2002-03-07

In this paper, we analyse the conditions for convergence towards general relativity of scalar-tensor gravity theories defined by an arbitrary coupling function {alpha} (in the Einstein frame). We show that, in general, the evolution of the scalar field ({phi}) is governed by two opposite mechanisms: an attraction mechanism which tends to drive scalar-tensor models towards Einstein's theory, and a repulsion mechanism which has the contrary effect. The attraction mechanism dominates the recent epochs of the universe evolution if, and only if, the scalar field and its derivative satisfy certain boundary conditions. Since these conditions for convergence towards general relativity depend on the particular scalar-tensor theory used to describe the universe evolution, the nucleosynthesis bounds on the present value of the coupling function, {alpha}{sub 0}, strongly differ from some theories to others. For example, in theories defined by {alpha} {proportional_to} |{phi}| analytical estimates lead to very stringent nucleosynthesis bounds on {alpha}{sub 0}({approx}<10{sup -19}). By contrast, in scalar-tensor theories defined by {alpha} {proportional_to} {phi} much larger limits on {alpha}{sub 0}({approx}<10{sup -7}) are found.

Multiplier convergent series and uniform convergence of mapping ...

Indian Academy of Sciences (India)

MS received 14 April 2011; revised 17 November 2012. Abstract. In this paper, we introduce the frame property of complex sequence sets and study the uniform convergence of nonlinear mapping series in β-dual of spaces consisting of multiplier convergent series. Keywords. Multiplier convergent series; mapping series. 1.

Convergent evolution of plant and animal embryo defences by hyperstable non-digestible storage proteins.

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Pasquevich, María Yanina; Dreon, Marcos Sebastián; Qiu, Jian-Wen; Mu, Huawei; Heras, Horacio

2017-11-20

Plants have evolved sophisticated embryo defences by kinetically-stable non-digestible storage proteins that lower the nutritional value of seeds, a strategy that have not been reported in animals. To further understand antinutritive defences in animals, we analysed PmPV1, massively accumulated in the eggs of the gastropod Pomacea maculata, focusing on how its structure and structural stability features affected its capacity to withstand passage through predator guts. The native protein withstands >50 min boiling and resists the denaturing detergent sodium dodecyl sulphate (SDS), indicating an unusually high structural stability (i.e., kinetic stability). PmPV1 is highly resistant to in vitro proteinase digestion and displays structural stability between pH 2.0-12.0 and 25-85 °C. Furthermore, PmPV1 withstands in vitro and mice digestion and is recovered unchanged in faeces, supporting an antinutritive defensive function. Subunit sequence similarities suggest a common origin and tolerance to mutations. This is the first known animal genus that, like plant seeds, lowers the nutritional value of eggs by kinetically-stable non-digestible storage proteins that survive the gut of predators unaffected. The selective pressure of the harsh gastrointestinal environment would have favoured their appearance, extending by convergent evolution the presence of plant-like hyperstable antinutritive proteins to unattended reproductive stages in animals.

Molecular evolution of the Paramyxoviridae and Rhabdoviridae multiple-protein-encoding P gene.

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Jordan, I K; Sutter, B A; McClure, M A

2000-01-01

Presented here is an analysis of the molecular evolutionary dynamics of the P gene among 76 representative sequences of the Paramyxoviridae and Rhabdoviridae RNA virus families. In a number of Paramyxoviridae taxa, as well as in vesicular stomatitis viruses of the Rhabdoviridae, the P gene encodes multiple proteins from a single genomic RNA sequence. These products include the phosphoprotein (P), as well as the C and V proteins. The complexity of the P gene makes it an intriguing locus to study from an evolutionary perspective. Amino acid sequence alignments of the proteins encoded at the P and N loci were used in independent phylogenetic reconstructions of the Paramyxoviridae and Rhabdoviridae families. P-gene-coding capacities were mapped onto the Paramyxoviridae phylogeny, and the most parsimonious path of multiple-coding-capacity evolution was determined. Levels of amino acid variation for Paramyxoviridae and Rhabdoviridae P-gene-encoded products were also analyzed. Proteins encoded in overlapping reading frames from the same nucleotides have different levels of amino acid variation. The nucleotide architecture that underlies the amino acid variation was determined in order to evaluate the role of selection in the evolution of the P gene overlapping reading frames. In every case, the evolution of one of the proteins encoded in the overlapping reading frames has been constrained by negative selection while the other has evolved more rapidly. The integrity of the overlapping reading frame that represents a derived state is generally maintained at the expense of the ancestral reading frame encoded by the same nucleotides. The evolution of such multicoding sequences is likely a response by RNA viruses to selective pressure to maximize genomic information content while maintaining small genome size. The ability to evolve such a complex genomic strategy is intimately related to the dynamics of the viral quasispecies, which allow enhanced exploration of the adaptive

Evolution of the stellar mass function in multiple-population globular clusters

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Vesperini, Enrico; Hong, Jongsuk; Webb, Jeremy J.; D'Antona, Franca; D'Ercole, Annibale

2018-05-01

We present the results of a survey of N-body simulations aimed at studying the effects of the long-term dynamical evolution on the stellar mass function (MF) of multiple stellar populations in globular clusters. Our simulations show that if first-(1G) and second-generation (2G) stars have the same initial MF (IMF), the global MFs of the two populations are affected similarly by dynamical evolution and no significant differences between the 1G and 2G MFs arise during the cluster's evolution. If the two populations have different IMFs, dynamical effects do not completely erase memory of the initial differences. Should observations find differences between the global 1G and 2G MFs, these would reveal the fingerprints of differences in their IMFs. Irrespective of whether the 1G and 2G populations have the same global IMF or not, dynamical effects can produce differences between the local (measured at various distances from the cluster centre) 1G and 2G MFs; these differences are a manifestation of the process of mass segregation in populations with different initial structural properties. In dynamically old and spatially mixed clusters, however, differences between the local 1G and 2G MFs can reveal differences between the 1G and 2G global MFs. In general, for clusters with any dynamical age, large differences between the local 1G and 2G MFs are more likely to be associated with differences in the global MF. Our study also reveals a dependence of the spatial mixing rate on the stellar mass, another dynamical consequence of the multiscale nature of multiple-population clusters.

Regularization methods for ill-posed problems in multiple Hilbert scales

International Nuclear Information System (INIS)

Mazzieri, Gisela L; Spies, Ruben D

2012-01-01

Several convergence results in Hilbert scales under different source conditions are proved and orders of convergence and optimal orders of convergence are derived. Also, relations between those source conditions are proved. The concept of a multiple Hilbert scale on a product space is introduced, and regularization methods on these scales are defined, both for the case of a single observation and for the case of multiple observations. In the latter case, it is shown how vector-valued regularization functions in these multiple Hilbert scales can be used. In all cases, convergence is proved and orders and optimal orders of convergence are shown. Finally, some potential applications and open problems are discussed. (paper)

Does morphological convergence imply functional similarity? A test using the evolution of quadrupedalism in ornithischian dinosaurs.

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Maidment, Susannah C R; Barrett, Paul M

2012-09-22

Convergent morphologies are thought to indicate functional similarity, arising because of a limited number of evolutionary or developmental pathways. Extant taxa displaying convergent morphologies are used as analogues to assess function in extinct taxa with similar characteristics. However, functional studies of extant taxa have shown that functional similarity can arise from differing morphologies, calling into question the paradigm that form and function are closely related. We test the hypothesis that convergent skeletal morphology indicates functional similarity in the fossil record using ornithischian dinosaurs. The rare transition from bipedality to quadrupedality occurred at least three times independently in this clade, resulting in a suite of convergent osteological characteristics. We use homology rather than analogy to provide an independent line of evidence about function, reconstructing soft tissues using the extant phylogenetic bracket and applying biomechanical concepts to produce qualitative assessments of muscle leverage. We also optimize character changes to investigate the sequence of character acquisition. Different lineages of quadrupedal ornithischian dinosaur stood and walked differently from each other, falsifying the hypothesis that osteological convergence indicates functional similarity. The acquisition of features correlated with quadrupedalism generally occurs in the same order in each clade, suggesting underlying developmental mechanisms that act as evolutionary constraints.

Convergent dynamics for multistable delayed neural networks

International Nuclear Information System (INIS)

Shih, Chih-Wen; Tseng, Jui-Pin

2008-01-01

This investigation aims at developing a methodology to establish convergence of dynamics for delayed neural network systems with multiple stable equilibria. The present approach is general and can be applied to several network models. We take the Hopfield-type neural networks with both instantaneous and delayed feedbacks to illustrate the idea. We shall construct the complete dynamical scenario which comprises exactly 2 n stable equilibria and exactly (3 n − 2 n ) unstable equilibria for the n-neuron network. In addition, it is shown that every solution of the system converges to one of the equilibria as time tends to infinity. The approach is based on employing the geometrical structure of the network system. Positively invariant sets and componentwise dynamical properties are derived under the geometrical configuration. An iteration scheme is subsequently designed to confirm the convergence of dynamics for the system. Two examples with numerical simulations are arranged to illustrate the present theory

Assessing the validity of discourse analysis: transdisciplinary convergence

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Jaipal-Jamani, Kamini

2014-12-01

Research studies using discourse analysis approaches make claims about phenomena or issues based on interpretation of written or spoken text, which includes images and gestures. How are findings/interpretations from discourse analysis validated? This paper proposes transdisciplinary convergence as a way to validate discourse analysis approaches to research. The argument is made that discourse analysis explicitly grounded in semiotics, systemic functional linguistics, and critical theory, offers a credible research methodology. The underlying assumptions, constructs, and techniques of analysis of these three theoretical disciplines can be drawn on to show convergence of data at multiple levels, validating interpretations from text analysis.

Parallel sites implicate functional convergence of the hearing gene prestin among echolocating mammals.

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Liu, Zhen; Qi, Fei-Yan; Zhou, Xin; Ren, Hai-Qing; Shi, Peng

2014-09-01

Echolocation is a sensory system whereby certain mammals navigate and forage using sound waves, usually in environments where visibility is limited. Curiously, echolocation has evolved independently in bats and whales, which occupy entirely different environments. Based on this phenotypic convergence, recent studies identified several echolocation-related genes with parallel sites at the protein sequence level among different echolocating mammals, and among these, prestin seems the most promising. Although previous studies analyzed the evolutionary mechanism of prestin, the functional roles of the parallel sites in the evolution of mammalian echolocation are not clear. By functional assays, we show that a key parameter of prestin function, 1/α, is increased in all echolocating mammals and that the N7T parallel substitution accounted for this functional convergence. Moreover, another parameter, V1/2, was shifted toward the depolarization direction in a toothed whale, the bottlenose dolphin (Tursiops truncatus) and a constant-frequency (CF) bat, the Stoliczka's trident bat (Aselliscus stoliczkanus). The parallel site of I384T between toothed whales and CF bats was responsible for this functional convergence. Furthermore, the two parameters (1/α and V1/2) were correlated with mammalian high-frequency hearing, suggesting that the convergent changes of the prestin function in echolocating mammals may play important roles in mammalian echolocation. To our knowledge, these findings present the functional patterns of echolocation-related genes in echolocating mammals for the first time and rigorously demonstrate adaptive parallel evolution at the protein sequence level, paving the way to insights into the molecular mechanism underlying mammalian echolocation. © The Author 2014. Published by Oxford University Press on behalf of the Society for Molecular Biology and Evolution. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

Evolution of technology convergence networks in Korea: Characteristics of temporal changes in R&D according to institution type

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Choi, Jae Young; Jeong, Seongkyoon

2018-01-01

This study investigates the temporal changes in development of technology convergence networks by institution type, i.e., public research institute (PRI), university and industry. Using the co-classification of technological domains of patents, we identified technology convergence of Korean patents, which were filed at Korea Intellectual Properties Office (KIPO) from 1997 to 2011. We conducted a network analysis at the technology level to search for the key technology fields and frequent instances of technology convergence. The results show that technology convergence networks have grown significantly in the recent period regardless of the institution type. While industries started to conspicuously engage in technology convergence in the late 1990s, universities or PRIs did not do so until the mid-2000s. This discrepancy in the phase of technology convergence is attributed to the temporal difference in R&D stage (e.g., basic research and commercial product development). Our findings imply that corporal and governmental R&D management decision on promising technology fields will be more effective if the decision makers carefully consider the type of R&D entity in analyzing technological landscapes. PMID:29420574

Evolution of technology convergence networks in Korea: Characteristics of temporal changes in R&D according to institution type.

Science.gov (United States)

Choi, Jae Young; Jeong, Seongkyoon; Jung, Jung-Kyu

2018-01-01

This study investigates the temporal changes in development of technology convergence networks by institution type, i.e., public research institute (PRI), university and industry. Using the co-classification of technological domains of patents, we identified technology convergence of Korean patents, which were filed at Korea Intellectual Properties Office (KIPO) from 1997 to 2011. We conducted a network analysis at the technology level to search for the key technology fields and frequent instances of technology convergence. The results show that technology convergence networks have grown significantly in the recent period regardless of the institution type. While industries started to conspicuously engage in technology convergence in the late 1990s, universities or PRIs did not do so until the mid-2000s. This discrepancy in the phase of technology convergence is attributed to the temporal difference in R&D stage (e.g., basic research and commercial product development). Our findings imply that corporal and governmental R&D management decision on promising technology fields will be more effective if the decision makers carefully consider the type of R&D entity in analyzing technological landscapes.

Concept for Mobility and Interconnections Aspects in Converged NGN-Based IPTV Architecture

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Eugen Mikoczy

2009-01-01

Full Text Available The progress and evolution trends in the area of ICT and ICT infrastructure based on convergence processes create new opportunities. Service providers and network operators can provide a wide spectrum of multimedia services and applications to end users. The IPTV services represent a specific group of multimedia services which are in the sphere of interest of the telecommunication technical community but also subscribers. Standardization bodies like ETSI TISPAN or ITU-T have defined standards for NGN-based IPTV architecture and services (IMS and non-IMS. The paper evaluates possibilities and potential architecture for concept of converged NGN IPTV. New vision of the converged NGN IPTV architecture is presented together with proposed enhancements compared to IMS-based IPTV where single converged platform can serve fixed, mobile, or wireless terminals. The concept for IPTV service roaming with mobility support and different interconnection scenarios are discussed with intention to show potential user benefits.

BRICS: Evolution and Convergence of Powers

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Vatanyar Saidovich Yagya

2016-12-01

Full Text Available Conducting of foreign policy solely by means of classical diplomacy today seems inefficient. States are supposed to use additional set of tools that have traditionally been at the confluence of soft and hard powers. Convergence of these concepts launched the emergence of such strategies, as smart power and hybrid power that we analyze as a system in relation to such a phenomenon, as BRICS. In the first part of paper we contemplate the concept of power and further expand it to the theoretical ground of each of these strategies along with the existing experience and prospects of their implementation in the BRICS countries. Systematic analysis is taken as the basis of the methodology of this paper, which allowed us to explore this theme separately for each of the BRICS countries and collectively as a system. Feasibility of a number of our provisions is confirmed by relevant case studies and analyses of the most relevant Russian and foreign literature, which results in our main conclusions. Current trends indicate that the BRICS countries are actively expanding its presence in all the key sectors of the global economy and politics. BRICS is at an early stage of implementation of own formats and tools of smart and hybrid powers, the role of which will steadily increase in the international activities of the group, adding value to its arsenal of traditional diplomacy. The potential capacity of soft, smart and hybrid powers of BRICS aims at helping countries to achieve a new level of integration and attractiveness in the eyes of the international community, and will also allow countries to strengthen their positions.

Using a zero-variance scheme to accelerate the fission source convergence in a Monte Carlo calculation

International Nuclear Information System (INIS)

Christoforou, S.; Hoogenboom, J. E.

2009-01-01

We have used Boltzmann entropy in order to test whether a zero-variance based scheme can speed up the fission source convergence in a Monte Carlo calculation. It is shown that the choice of the initial source distribution significantly influences the evolution of the source, even leading to cases where the source does not converge at all throughout the calculation. The results from a loosely coupled system based on the NEA/OECD source convergence benchmarks indicate that, when using a biasing scheme such as the one we have developed, there can be significant improvement in the convergence, up to 3 times faster, which coupled with an figure of merit improvement of 1.5 leads to more efficient calculations. (authors)

Segment-Specific Adhesion as a Driver of Convergent Extension

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Vroomans, Renske M. A.; Hogeweg, Paulien; ten Tusscher, Kirsten H. W. J.

2015-01-01

Convergent extension, the simultaneous extension and narrowing of tissues, is a crucial event in the formation of the main body axis during embryonic development. It involves processes on multiple scales: the sub-cellular, cellular and tissue level, which interact via explicit or intrinsic feedback mechanisms. Computational modelling studies play an important role in unravelling the multiscale feedbacks underlying convergent extension. Convergent extension usually operates in tissue which has been patterned or is currently being patterned into distinct domains of gene expression. How such tissue patterns are maintained during the large scale tissue movements of convergent extension has thus far not been investigated. Intriguingly, experimental data indicate that in certain cases these tissue patterns may drive convergent extension rather than requiring safeguarding against convergent extension. Here we use a 2D Cellular Potts Model (CPM) of a tissue prepatterned into segments, to show that convergent extension tends to disrupt this pre-existing segmental pattern. However, when cells preferentially adhere to cells of the same segment type, segment integrity is maintained without any reduction in tissue extension. Strikingly, we demonstrate that this segment-specific adhesion is by itself sufficient to drive convergent extension. Convergent extension is enhanced when we endow our in silico cells with persistence of motion, which in vivo would naturally follow from cytoskeletal dynamics. Finally, we extend our model to confirm the generality of our results. We demonstrate a similar effect of differential adhesion on convergent extension in tissues that can only extend in a single direction (as often occurs due to the inertia of the head region of the embryo), and in tissues prepatterned into a sequence of domains resulting in two opposing adhesive gradients, rather than alternating segments. PMID:25706823

Quaternary tectonic evolution of the Pamir-Tian Shan convergence zone, Northwest China

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Thompson Jobe, Jessica Ann; Li, Tao; Chen, Jie; Burbank, Douglas W.; Bufe, Aaron

2017-12-01

The Pamir-Tian Shan collision zone in the western Tarim Basin, northwest China, formed from rapid and ongoing convergence in response to the Indo-Eurasian collision. The arid landscape preserves suites of fluvial terraces crossing structures active since the late Neogene that create fault and fold scarps recording Quaternary deformation. Using geologic and geomorphic mapping, differential GPS surveys of deformed terraces, and optically stimulated luminescence dating, we create a synthesis of the active structures that delineate the timing, rate, and migration of Quaternary deformation during ongoing convergence. New deformation rates on eight faults and folds, when combined with previous studies, highlight the spatial and temporal patterns of deformation within the Pamir-Tian Shan convergence zone during the Quaternary. Terraces spanning 130 to 8 ka record deformation rates between 0.1 and 5.6 mm/yr on individual structures. In the westernmost Tarim Basin, where the Pamir and Tian Shan are already juxtaposed, the fastest rates occur on actively deforming structures at the interface of the Pamir-Tian Shan orogens. Farther east, as the separation between the Pamir-Tian Shan orogens increases, the deformation has not been concentrated on a single structure, but rather has been concurrently distributed across a zone of faults and folds in the Kashi-Atushi fold-and-thrust belt and along the NE Pamir margin, where shortening rates vary on individual structures during the Quaternary. Although numerous structures accommodate the shortening and the locus of deformation shifts during the Quaternary, the total shortening across the western Tarim Basin has remained steady and approximately matches the current geodetic rate of 6-9 mm/yr.

An Eocene orthocone from Antarctica shows convergent evolution of internally shelled cephalopods

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Bengtson, Stefan; Reguero, Marcelo A.; Mörs, Thomas

2017-01-01

Background The Subclass Coleoidea (Class Cephalopoda) accommodates the diverse present-day internally shelled cephalopod mollusks (Spirula, Sepia and octopuses, squids, Vampyroteuthis) and also extinct internally shelled cephalopods. Recent Spirula represents a unique coleoid retaining shell structures, a narrow marginal siphuncle and globular protoconch that signify the ancestry of the subclass Coleoidea from the Paleozoic subclass Bactritoidea. This hypothesis has been recently supported by newly recorded diverse bactritoid-like coleoids from the Carboniferous of the USA, but prior to this study no fossil cephalopod indicative of an endochochleate branch with an origin independent from subclass Bactritoidea has been reported. Methodology/Principal findings Two orthoconic conchs were recovered from the Early Eocene of Seymour Island at the tip of the Antarctic Peninsula, Antarctica. They have loosely mineralized organic-rich chitin-compatible microlaminated shell walls and broadly expanded central siphuncles. The morphological, ultrustructural and chemical data were determined and characterized through comparisons with extant and extinct taxa using Scanning Electron Microscopy/Energy Dispersive Spectrometry (SEM/EDS). Conclusions/Significance Our study presents the first evidence for an evolutionary lineage of internally shelled cephalopods with independent origin from Bactritoidea/Coleoidea, indicating convergent evolution with the subclass Coleoidea. A new subclass Paracoleoidea Doguzhaeva n. subcl. is established for accommodation of orthoconic cephalopods with the internal shell associated with a broadly expanded central siphuncle. Antarcticerida Doguzhaeva n. ord., Antarcticeratidae Doguzhaeva n. fam., Antarcticeras nordenskjoeldi Doguzhaeva n. gen., n. sp. are described within the subclass Paracoleoidea. The analysis of organic-rich shell preservation of A. nordenskjoeldi by use of SEM/EDS techniques revealed fossilization of hyposeptal cameral soft tissues

The toxicogenomic multiverse: convergent recruitment of proteins into animal venoms.

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Fry, Bryan G; Roelants, Kim; Champagne, Donald E; Scheib, Holger; Tyndall, Joel D A; King, Glenn F; Nevalainen, Timo J; Norman, Janette A; Lewis, Richard J; Norton, Raymond S; Renjifo, Camila; de la Vega, Ricardo C Rodríguez

2009-01-01

Throughout evolution, numerous proteins have been convergently recruited into the venoms of various animals, including centipedes, cephalopods, cone snails, fish, insects (several independent venom systems), platypus, scorpions, shrews, spiders, toxicoferan reptiles (lizards and snakes), and sea anemones. The protein scaffolds utilized convergently have included AVIT/colipase/prokineticin, CAP, chitinase, cystatin, defensins, hyaluronidase, Kunitz, lectin, lipocalin, natriuretic peptide, peptidase S1, phospholipase A(2), sphingomyelinase D, and SPRY. Many of these same venom protein types have also been convergently recruited for use in the hematophagous gland secretions of invertebrates (e.g., fleas, leeches, kissing bugs, mosquitoes, and ticks) and vertebrates (e.g., vampire bats). Here, we discuss a number of overarching structural, functional, and evolutionary generalities of the protein families from which these toxins have been frequently recruited and propose a revised and expanded working definition for venom. Given the large number of striking similarities between the protein compositions of conventional venoms and hematophagous secretions, we argue that the latter should also fall under the same definition.

Analysis of economic convergence through synthetic development indicators: the chilean case study

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Víctor Fernando Figueroa Arcila

2003-01-01

Full Text Available This paper defends the use of convergence models to study the temporary evolution of the Chilean communes’ socioeconomic development. To do so, we will use an indicator made up of using multivariate analysis techniques. By means of regression models of transversal section and models of distributional dynamics we will outline, on the basis of the historic function of communal economies, the behaviour expected for those economies in future and, therefore, the tendencial evolution of Chilean territorial economic model.

Monte Carlo source convergence and the Whitesides problem

International Nuclear Information System (INIS)

Blomquist, R. N.

2000-01-01

The issue of fission source convergence in Monte Carlo eigenvalue calculations is of interest because of the potential consequences of erroneous criticality safety calculations. In this work, the authors compare two different techniques to improve the source convergence behavior of standard Monte Carlo calculations applied to challenging source convergence problems. The first method, super-history powering, attempts to avoid discarding important fission sites between generations by delaying stochastic sampling of the fission site bank until after several generations of multiplication. The second method, stratified sampling of the fission site bank, explicitly keeps the important sites even if conventional sampling would have eliminated them. The test problems are variants of Whitesides' Criticality of the World problem in which the fission site phase space was intentionally undersampled in order to induce marginally intolerable variability in local fission site populations. Three variants of the problem were studied, each with a different degree of coupling between fissionable pieces. Both the superhistory powering method and the stratified sampling method were shown to improve convergence behavior, although stratified sampling is more robust for the extreme case of no coupling. Neither algorithm completely eliminates the loss of the most important fissionable piece, and if coupling is absent, the lost piece cannot be recovered unless its sites from earlier generations have been retained. Finally, criteria for measuring source convergence reliability are proposed and applied to the test problems

Convergent evolution of germ granule nucleators: A hypothesis.

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Kulkarni, Arpita; Extavour, Cassandra G

2017-10-01

Germ cells have been considered "the ultimate stem cell" because they alone, during normal development of sexually reproducing organisms, are able to give rise to all organismal cell types. Morphological descriptions of a specialized cytoplasm termed 'germ plasm' and associated electron dense ribonucleoprotein (RNP) structures called 'germ granules' within germ cells date back as early as the 1800s. Both germ plasm and germ granules are implicated in germ line specification across metazoans. However, at a molecular level, little is currently understood about the molecular mechanisms that assemble these entities in germ cells. The discovery that in some animals, the gene products of a small number of lineage-specific genes initiate the assembly (also termed nucleation) of germ granules and/or germ plasm is the first step towards facilitating a better understanding of these complex biological processes. Here, we draw on research spanning over 100years that supports the hypothesis that these nucleator genes may have evolved convergently, allowing them to perform analogous roles across animal lineages. Copyright © 2017 The Authors. Published by Elsevier B.V. All rights reserved.

Experimental evidence for convergent evolution of maternal care heuristics in industrialized and small-scale populations.

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Kushnick, Geoff; Hanowell, Ben; Kim, Jun-Hong; Langstieh, Banrida; Magnano, Vittorio; Oláh, Katalin

2015-06-01

Maternal care decision rules should evolve responsiveness to factors impinging on the fitness pay-offs of care. Because the caretaking environments common in industrialized and small-scale societies vary in predictable ways, we hypothesize that heuristics guiding maternal behaviour will also differ between these two types of populations. We used a factorial vignette experiment to elicit third-party judgements about likely caretaking decisions of a hypothetical mother and her child when various fitness-relevant factors (maternal age and access to resources, and offspring age, sex and quality) were varied systematically in seven populations-three industrialized and four small-scale. Despite considerable variation in responses, we found that three of five main effects, and the two severity effects, exhibited statistically significant industrialized/ small-scale population differences. All differences could be explained as adaptive solutions to industrialized versus small-scale caretaking environments. Further, we found gradients in the relationship between the population-specific estimates and national-level socio-economic indicators, further implicating important aspects of the variation in industrialized and small-scale caretaking environments in shaping heuristics. Although there is mounting evidence for a genetic component to human maternal behaviour, there is no current evidence for interpopulation variation in candidate genes. We nonetheless suggest that heuristics guiding maternal behaviour in diverse societies emerge via convergent evolution in response to similar selective pressures.

ANALYSIS OF CONVERGENCE WITHIN THE EUROPEAN UNION SIGMA AND BETA CONVERGENCE

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Begu Liviu-Stelian

2010-12-01

Full Text Available Real convergence study began with the development of neoclassical models of growth and especially with the passage of econometric applications of these models. In this paper we present applications of indicators and patterns of convergence on the example of European Union member countries and some current economic impact assessments on European convergence process. This analysis is based on the estimated a- and b convergence and on Markov chains. The study deals with the economic convergence of the European countries and especially the convergence of the EU countries, including Romania. In the end of the study presents several economic scenarios for a faster and easier exit from the current crisis in Romania.

On the distinction between density and luminosity evolution

International Nuclear Information System (INIS)

Bahcall, J.N.

1977-01-01

It is shown that the assumptions of pure density evolution and pure luminosity evolution lead to observable differences in the distribution of sources for all convergent luminosity functions. The proof given is valid for sources with an arbitrary number of intrinisic luminosities (e.g., optical, infrared, and radio) and also holds in the special cases of mixed evolution that are considered. (author)

Shock wave focusing in water inside convergent structures

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C Wang

2016-09-01

Full Text Available Experiments on shock focusing in water-filled convergent structures have been performed. A shock wave in water is generated by means of a projectile, launched from a gas gun, which impacts a water-filled convergent structure. Two types of structures have been tested; a bulk material and a thin shell structure. The geometric shape of the convergent structures is given by a logarithmic spiral, and this particular shape is chosen because it maximizes the amount of energy reaching the focal region. High-speed schlieren photography is used to visualize the shock dynamics during the focusing event. Results show that the fluid-structure interaction between the thin shell structure and the shock wave in the water is different from that of a bulk structure; multiple reflections of the shock wave inside the thin shell are reflected back into the water, thus creating a wave train, which is not observed for shock focusing in a bulk material.

Ancient mitochondrial DNA reveals convergent evolution of giant short-faced bears (Tremarctinae) in North and South America.

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Mitchell, Kieren J; Bray, Sarah C; Bover, Pere; Soibelzon, Leopoldo; Schubert, Blaine W; Prevosti, Francisco; Prieto, Alfredo; Martin, Fabiana; Austin, Jeremy J; Cooper, Alan

2016-04-01

The Tremarctinae are a subfamily of bears endemic to the New World, including two of the largest terrestrial mammalian carnivores that have ever lived: the giant, short-faced bears Arctodus simus from North America and Arctotherium angustidens from South America (greater than or equal to 1000 kg). Arctotherium angustidens became extinct during the Early Pleistocene, whereas Arctodus simus went extinct at the very end of the Pleistocene. The only living tremarctine is the spectacled bear (Tremarctos ornatus), a largely herbivorous bear that is today only found in South America. The relationships among the spectacled bears (Tremarctos), South American short-faced bears (Arctotherium) and North American short-faced bears (Arctodus) remain uncertain. In this study, we sequenced a mitochondrial genome from an Arctotherium femur preserved in a Chilean cave. Our molecular phylogenetic analyses revealed that the South American short-faced bears were more closely related to the extant South American spectacled bear than to the North American short-faced bears. This result suggests striking convergent evolution of giant forms in the two groups of short-faced bears (Arctodus and Arctotherium), potentially as an adaptation to dominate competition for megafaunal carcasses. © 2016 The Author(s).

Accelerating Markov chain Monte Carlo simulation by differential evolution with self-adaptive randomized subspace sampling

Energy Technology Data Exchange (ETDEWEB)

Vrugt, Jasper A [Los Alamos National Laboratory; Hyman, James M [Los Alamos National Laboratory; Robinson, Bruce A [Los Alamos National Laboratory; Higdon, Dave [Los Alamos National Laboratory; Ter Braak, Cajo J F [NETHERLANDS; Diks, Cees G H [UNIV OF AMSTERDAM

2008-01-01

Markov chain Monte Carlo (MCMC) methods have found widespread use in many fields of study to estimate the average properties of complex systems, and for posterior inference in a Bayesian framework. Existing theory and experiments prove convergence of well constructed MCMC schemes to the appropriate limiting distribution under a variety of different conditions. In practice, however this convergence is often observed to be disturbingly slow. This is frequently caused by an inappropriate selection of the proposal distribution used to generate trial moves in the Markov Chain. Here we show that significant improvements to the efficiency of MCMC simulation can be made by using a self-adaptive Differential Evolution learning strategy within a population-based evolutionary framework. This scheme, entitled DiffeRential Evolution Adaptive Metropolis or DREAM, runs multiple different chains simultaneously for global exploration, and automatically tunes the scale and orientation of the proposal distribution in randomized subspaces during the search. Ergodicity of the algorithm is proved, and various examples involving nonlinearity, high-dimensionality, and multimodality show that DREAM is generally superior to other adaptive MCMC sampling approaches. The DREAM scheme significantly enhances the applicability of MCMC simulation to complex, multi-modal search problems.

Multiple Active Contours Guided by Differential Evolution for Medical Image Segmentation

Science.gov (United States)

Cruz-Aceves, I.; Avina-Cervantes, J. G.; Lopez-Hernandez, J. M.; Rostro-Gonzalez, H.; Garcia-Capulin, C. H.; Torres-Cisneros, M.; Guzman-Cabrera, R.

2013-01-01

This paper presents a new image segmentation method based on multiple active contours guided by differential evolution, called MACDE. The segmentation method uses differential evolution over a polar coordinate system to increase the exploration and exploitation capabilities regarding the classical active contour model. To evaluate the performance of the proposed method, a set of synthetic images with complex objects, Gaussian noise, and deep concavities is introduced. Subsequently, MACDE is applied on datasets of sequential computed tomography and magnetic resonance images which contain the human heart and the human left ventricle, respectively. Finally, to obtain a quantitative and qualitative evaluation of the medical image segmentations compared to regions outlined by experts, a set of distance and similarity metrics has been adopted. According to the experimental results, MACDE outperforms the classical active contour model and the interactive Tseng method in terms of efficiency and robustness for obtaining the optimal control points and attains a high accuracy segmentation. PMID:23983809

Multiple Active Contours Guided by Differential Evolution for Medical Image Segmentation

Directory of Open Access Journals (Sweden)

I. Cruz-Aceves

2013-01-01

Full Text Available This paper presents a new image segmentation method based on multiple active contours guided by differential evolution, called MACDE. The segmentation method uses differential evolution over a polar coordinate system to increase the exploration and exploitation capabilities regarding the classical active contour model. To evaluate the performance of the proposed method, a set of synthetic images with complex objects, Gaussian noise, and deep concavities is introduced. Subsequently, MACDE is applied on datasets of sequential computed tomography and magnetic resonance images which contain the human heart and the human left ventricle, respectively. Finally, to obtain a quantitative and qualitative evaluation of the medical image segmentations compared to regions outlined by experts, a set of distance and similarity metrics has been adopted. According to the experimental results, MACDE outperforms the classical active contour model and the interactive Tseng method in terms of efficiency and robustness for obtaining the optimal control points and attains a high accuracy segmentation.

Science and technology convergence: with emphasis for nanotechnology-inspired convergence

Energy Technology Data Exchange (ETDEWEB)

Bainbridge, William S.; Roco, Mihail C., E-mail: mroco@nsf.gov [National Science Foundation (United States)

2016-07-15

Convergence offers a new universe of discovery, innovation, and application opportunities through specific theories, principles, and methods to be implemented in research, education, production, and other societal activities. Using a holistic approach with shared goals, convergence seeks to transcend existing human limitations to achieve improved conditions for work, learning, aging, physical, and cognitive wellness. This paper outlines ten key theories that offer complementary perspectives on this complex dynamic. Principles and methods are proposed to facilitate and enhance science and technology convergence. Several convergence success stories in the first part of the 21st century—including nanotechnology and other emerging technologies—are discussed in parallel with case studies focused on the future. The formulation of relevant theories, principles, and methods aims at establishing the convergence science.

Science and technology convergence: with emphasis for nanotechnology-inspired convergence

International Nuclear Information System (INIS)

Bainbridge, William S.; Roco, Mihail C.

2016-01-01

Convergence offers a new universe of discovery, innovation, and application opportunities through specific theories, principles, and methods to be implemented in research, education, production, and other societal activities. Using a holistic approach with shared goals, convergence seeks to transcend existing human limitations to achieve improved conditions for work, learning, aging, physical, and cognitive wellness. This paper outlines ten key theories that offer complementary perspectives on this complex dynamic. Principles and methods are proposed to facilitate and enhance science and technology convergence. Several convergence success stories in the first part of the 21st century—including nanotechnology and other emerging technologies—are discussed in parallel with case studies focused on the future. The formulation of relevant theories, principles, and methods aims at establishing the convergence science.

Understanding for convergence monitoring for probabilistic risk assessment based on Markov Chain Monte Carlo Simulation

International Nuclear Information System (INIS)

Kim, Joo Yeon; Jang, Han Ki; Jang, Sol Ah; Park, Tae Jin

2014-01-01

There is a question that the simulation actually leads to draws from its target distribution and the most basic one is whether such Markov chains can always be constructed and all chain values sampled from them. The problem to be solved is the determination of how large this iteration should be to achieve the target distribution. This problem can be answered as convergence monitoring. In this paper, two widely used methods, such as autocorrelation and potential scale reduction factor (PSRF) in MCMC are characterized. There is no general agreement on the subject of the convergence. Although it is generally agreed that running n parallel chains in practice is computationally inefficient and unnecessary, running multiple parallel chains is generally applied for the convergence monitoring due to easy implementation. The main debate is the number of parallel chains needed. If the convergence properties of the chain are well understood then clearly a single chain suffices. Therefore, autocorrelation using single chain and multiple parallel ones are tried and their results then compared with each other in this study. And, the following question is answered from the two convergence results: Have the Markov chain realizations for achieved the target distribution?

Repeated and time-correlated morphological convergence in cave-dwelling harvestmen (Opiliones, Laniatores from Montane Western North America.

Directory of Open Access Journals (Sweden)

Shahan Derkarabetian

Full Text Available BACKGROUND: Many cave-dwelling animal species display similar morphologies (troglomorphism that have evolved convergent within and among lineages under the similar selective pressures imposed by cave habitats. Here we study such ecomorphological evolution in cave-dwelling Sclerobuninae harvestmen (Opiliones from the western United States, providing general insights into morphological homoplasy, rates of morphological change, and the temporal context of cave evolution. METHODOLOGY/PRINCIPAL FINDINGS: We gathered DNA sequence data from three independent gene regions, and combined these data with Bayesian hypothesis testing, morphometrics analysis, study of penis morphology, and relaxed molecular clock analyses. Using multivariate morphometric analysis, we find that phylogenetically unrelated taxa have convergently evolved troglomorphism; alternative phylogenetic hypotheses involving less morphological convergence are not supported by Bayesian hypothesis testing. In one instance, this morphology is found in specimens from a high-elevation stony debris habitat, suggesting that troglomorphism can evolve in non-cave habitats. We discovered a strong positive relationship between troglomorphy index and relative divergence time, making it possible to predict taxon age from morphology. Most of our time estimates for the origin of highly-troglomorphic cave forms predate the Pleistocene. CONCLUSIONS/SIGNIFICANCE: While several regions in the eastern and central United States are well-known hotspots for cave evolution, few modern phylogenetic studies have addressed the evolution of cave-obligate species in the western United States. Our integrative studies reveal the recurrent evolution of troglomorphism in a perhaps unexpected geographic region, at surprisingly deep time depths, and in sometimes surprising habitats. Because some newly discovered troglomorphic populations represent undescribed species, our findings stress the need for further biological

Ecomorphological convergence in planktivorous surgeonfishes

KAUST Repository

Friedman, S. T.

2016-01-26

© 2016 European Society For Evolutionary Biology. Morphological convergence plays a central role in the study of evolution. Often induced by shared ecological specialization, homoplasy hints at underlying selective pressures and adaptive constraints that deterministically shape the diversification of life. Although midwater zooplanktivory has arisen in adult surgeonfishes (family Acanthuridae) at least four independent times, it represents a clearly specialized state, requiring the capacity to swiftly swim in midwater locating and sucking small prey items. Whereas this diet has commonly been associated with specific functional adaptations in fishes, acanthurids present an interesting case study as all nonplanktivorous species feed by grazing on benthic algae and detritus, requiring a vastly different functional morphology that emphasizes biting behaviours. We examined the feeding morphology in 30 acanthurid species and, combined with a pre-existing phylogenetic tree, compared the fit of evolutionary models across two diet regimes: zooplanktivores and nonzooplanktivorous grazers. Accounting for phylogenetic relationships, the best-fitting model indicates that zooplanktivorous species are converging on a separate adaptive peak from their grazing relatives. Driving this bimodal landscape, zooplanktivorous acanthurids tend to develop a slender body, reduced facial features, smaller teeth and weakened jaw adductor muscles. However, despite these phenotypic changes, model fitting suggests that lineages have not yet reached the adaptive peak associated with plankton feeding even though some transitions appear to be over 10 million years old. These findings demonstrate that the selective demands of pelagic feeding promote repeated - albeit very gradual - ecomorphological convergence within surgeonfishes, while allowing local divergences between closely related species, contributing to the overall diversity of the clade. Journal of Evolutionary Biology

Ecomorphological convergence in planktivorous surgeonfishes.

Science.gov (United States)

Friedman, S T; Price, S A; Hoey, A S; Wainwright, P C

2016-05-01

Morphological convergence plays a central role in the study of evolution. Often induced by shared ecological specialization, homoplasy hints at underlying selective pressures and adaptive constraints that deterministically shape the diversification of life. Although midwater zooplanktivory has arisen in adult surgeonfishes (family Acanthuridae) at least four independent times, it represents a clearly specialized state, requiring the capacity to swiftly swim in midwater locating and sucking small prey items. Whereas this diet has commonly been associated with specific functional adaptations in fishes, acanthurids present an interesting case study as all nonplanktivorous species feed by grazing on benthic algae and detritus, requiring a vastly different functional morphology that emphasizes biting behaviours. We examined the feeding morphology in 30 acanthurid species and, combined with a pre-existing phylogenetic tree, compared the fit of evolutionary models across two diet regimes: zooplanktivores and nonzooplanktivorous grazers. Accounting for phylogenetic relationships, the best-fitting model indicates that zooplanktivorous species are converging on a separate adaptive peak from their grazing relatives. Driving this bimodal landscape, zooplanktivorous acanthurids tend to develop a slender body, reduced facial features, smaller teeth and weakened jaw adductor muscles. However, despite these phenotypic changes, model fitting suggests that lineages have not yet reached the adaptive peak associated with plankton feeding even though some transitions appear to be over 10 million years old. These findings demonstrate that the selective demands of pelagic feeding promote repeated - albeit very gradual - ecomorphological convergence within surgeonfishes, while allowing local divergences between closely related species, contributing to the overall diversity of the clade. © 2016 European Society For Evolutionary Biology. Journal of Evolutionary Biology © 2016 European

IT-BT convergence technology

International Nuclear Information System (INIS)

2012-12-01

This book explains IT-BT convergence technology as the future technology, which includes a prolog, easy IT-BT convergence technology that has infinite potentials for new value, policy of IT-BT convergence technology showing the potential of smart Korea, IT-BT convergence opening happy future, for the new future of IT powerful nation Korea with IT-BT convergence technology and an epilogue. This book reveals the conception, policy, performance and future of IT-BT convergence technology.

Converged wireline and wireless signal distribution in optical fiber access networks

DEFF Research Database (Denmark)

Prince, Kamau

This thesis presents results obtained during the course of my doctoral studies into the transport of fixed and wireless signaling over a converged otpical access infrastructure. In the formulation, development and assessment of a converged paradigma for multiple-services delivery via optical access...... networking infrastructure, I have demonstrated increased functionalities with existing optical technologies and commercially available optoelectronic devices. I have developed novel systems for extending the range of optical access systems, and have demonstrated the repurposing of standard digital devices...

Magnetically-Driven Convergent Instability Growth platform on Z.

Energy Technology Data Exchange (ETDEWEB)

Knapp, Patrick [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Mattsson, Thomas [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Martin, Matthew [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Benage, John F. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Jenkins, James [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Albright, Brian James [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

2017-09-01

Hydrodynamic instability growth is a fundamentally limiting process in many applications. In High Energy Density Physics (HEDP) systems such as inertial confinement fusion implosions and stellar explosions, hydro instabilities can dominate the evolution of the object and largely determine the final state achievable. Of particular interest is the process by which instabilities cause perturbations at a density or material interface to grow nonlinearly, introducing vorticity and eventually causing the two species to mix across the interface. Although quantifying instabilities has been the subject of many investigations in planar geometry, few have been done in converging geometry. During FY17, the team executed six convergent geometry instability experiments. Based on earlier results, the platform was redesigned and improved with respect to load centering at installation making the installation reproducible and development of a new 7.2 keV, Co He-a backlighter system to better penetrate the liner. Together, the improvements yielded significantly improved experimental results. The results in FY17 demonstrate the viability of using experiments on Z to quantify instability growth in cylindrically convergent geometry. Going forward, we will continue the partnership with staff and management at LANL to analyze the past experiments, compare to hydrodynamics growth models, and design future experiments.

TWO-FLUID MAGNETOHYDRODYNAMICS SIMULATIONS OF CONVERGING H I FLOWS IN THE INTERSTELLAR MEDIUM. II. ARE MOLECULAR CLOUDS GENERATED DIRECTLY FROM A WARM NEUTRAL MEDIUM?

International Nuclear Information System (INIS)

Inoue, Tsuyoshi; Inutsuka, Shu-ichiro

2009-01-01

Formation of interstellar clouds as a consequence of thermal instability is studied using two-dimensional two-fluid magnetohydrodynamic simulations. We consider the situation of converging, supersonic flows of warm neutral medium in the interstellar medium that generate a shocked slab of thermally unstable gas in which clouds form. We find, as speculated in Paper I, that in the shocked slab magnetic pressure dominates thermal pressure and the thermal instability grows in the isochorically cooling, thermally unstable slab that leads to the formation of H I clouds whose number density is typically n ∼ -3 , even if the angle between magnetic field and converging flows is small. We also find that even if there is a large dispersion of magnetic field, evolution of the shocked slab is essentially determined by the angle between the mean magnetic field and converging flows. Thus, the direct formation of molecular clouds by piling up warm neutral medium does not seem to be a typical molecular cloud formation process, unless the direction of supersonic converging flows is biased to the orientation of mean magnetic field by some mechanism. However, when the angle is small, the H I shell generated as a result of converging flows is massive and possibly evolves into molecular clouds, provided gas in the massive H I shell is piled up again along the magnetic field line. We expect that another subsequent shock wave can again pile up the gas of the massive shell and produce a larger cloud. We thus emphasize the importance of multiple episodes of converging flows, as a typical formation process of molecular clouds.

Particle Acceleration in Two Converging Shocks

Energy Technology Data Exchange (ETDEWEB)

Wang, Xin; Wang, Na; Shan, Hao [Xinjiang Astronomical Observatory, Chinese Academy of Sciences, Urumqi 830011 (China); Giacalone, Joe [Lunar and Planetary Laboratory, University of Arizona, Tucson AZ 85721 (United States); Yan, Yihua [CAS Key Laboratory of Solar Activity, National Astronomical Observatories, Beijing 100012 (China); Ding, Mingde, E-mail: wangxin@xao.ac.cn [Key Laboratory of Modern Astronomy and Astrophysics (Nanjing University) Ministry of Education, Nanjing 210093 (China)

2017-06-20

Observations by spacecraft such as ACE , STEREO , and others show that there are proton spectral “breaks” with energy E {sub br} at 1–10 MeV in some large CME-driven shocks. Generally, a single shock with the diffusive acceleration mechanism would not predict the “broken” energy spectrum. The present paper focuses on two converging shocks to identify this energy spectral feature. In this case, the converging shocks comprise one forward CME-driven shock on 2006 December 13 and another backward Earth bow shock. We simulate the detailed particle acceleration processes in the region of the converging shocks using the Monte Carlo method. As a result, we not only obtain an extended energy spectrum with an energy “tail” up to a few 10 MeV higher than that in previous single shock model, but also we find an energy spectral “break” occurring on ∼5.5 MeV. The predicted energy spectral shape is consistent with observations from multiple spacecraft. The spectral “break,” then, in this case is caused by the interaction between the CME shock and Earth’s bow shock, and otherwise would not be present if Earth were not in the path of the CME.

Acceleration and increased control of convergence in criticality calculations

International Nuclear Information System (INIS)

Jinaphanh, Alexis

2014-01-01

IRSN is developing a numerical simulation code called Moret to assess the nuclear criticality risk. This tool is designed to perform 3D simulations of neutron transport in a given system. It achieves this by adopting a probabilistic approach known as Monte Carlo, in which the transport of several successive generations of neutrons is calculated from an initial neutron distribution in the system under study. These generations are simulated until it is considered that convergence of the effective neutron multiplication coefficient (or K eff ) - which characterizes the gap before reaching the critical state - has been reached. Insufficient convergence can lead to underestimation of both K eff and the criticality risk. During this thesis work, A. Jinaphanh sought to improve the reliability of values by developing a new method for initializing calculations, together with a criterion used to reliably determine whether or not convergence has been reached. (author)

A Differential Evolution Based MPPT Method for Photovoltaic Modules under Partial Shading Conditions

Directory of Open Access Journals (Sweden)

Kok Soon Tey

2014-01-01

Full Text Available Partially shaded photovoltaic (PV modules have multiple peaks in the power-voltage (P-V characteristic curve and conventional maximum power point tracking (MPPT algorithm, such as perturbation and observation (P&O, which is unable to track the global maximum power point (GMPP accurately due to its localized search space. Therefore, this paper proposes a differential evolution (DE based optimization algorithm to provide the globalized search space to track the GMPP. The direction of mutation in the DE algorithm is modified to ensure that the mutation always converges to the best solution among all the particles in the generation. This helps to provide the rapid convergence of the algorithm. Simulation of the proposed PV system is carried out in PSIM and the results are compared to P&O algorithm. In the hardware implementation, a high step-up DC-DC converter is employed to verify the proposed algorithm experimentally on partial shading conditions, load variation, and solar intensity variation. The experimental results show that the proposed algorithm is able to converge to the GMPP within 1.2 seconds with higher efficiency than P&O.

Plankton dynamics associated with the convergence zone of a shear ...

African Journals Online (AJOL)

Multiple linear regression was used to determine the relationships between water quality variables and plankton abundances. Community analysis was also run on the data in order to determine community dynamics associated with frontal system convergence and downwelling. Key words: ichthyoplankton, phytoplankton, ...

On the convergence of finite state mean-field games through Γ-convergence

KAUST Repository

Ferreira, Rita C.; Gomes, Diogo A.

2014-01-01

In this study, we consider the long-term convergence (trend toward an equilibrium) of finite state mean-field games using Γ-convergence. Our techniques are based on the observation that an important class of mean-field games can be viewed as the Euler-Lagrange equation of a suitable functional. Therefore, using a scaling argument, one can convert a long-term convergence problem into a Γ-convergence problem. Our results generalize previous results related to long-term convergence for finite state problems. © 2014 Elsevier Inc.

On the convergence of finite state mean-field games through Γ-convergence

KAUST Repository

Ferreira, Rita C.

2014-10-01

In this study, we consider the long-term convergence (trend toward an equilibrium) of finite state mean-field games using Γ-convergence. Our techniques are based on the observation that an important class of mean-field games can be viewed as the Euler-Lagrange equation of a suitable functional. Therefore, using a scaling argument, one can convert a long-term convergence problem into a Γ-convergence problem. Our results generalize previous results related to long-term convergence for finite state problems. © 2014 Elsevier Inc.

Convergence results for a class of abstract continuous descent methods

Directory of Open Access Journals (Sweden)

Sergiu Aizicovici

2004-03-01

Full Text Available We study continuous descent methods for the minimization of Lipschitzian functions defined on a general Banach space. We establish convergence theorems for those methods which are generated by approximate solutions to evolution equations governed by regular vector fields. Since the complement of the set of regular vector fields is $sigma$-porous, we conclude that our results apply to most vector fields in the sense of Baire's categories.

Network Convergence

Indian Academy of Sciences (India)

First page Back Continue Last page Overview Graphics. Network Convergence. User is interested in application and content - not technical means of distribution. Boundaries between distribution channels fade out. Network convergence leads to seamless application and content solutions.

Widespread neural oscillations in the delta band dissociate rule convergence from rule divergence during creative idea generation

NARCIS (Netherlands)

Boot, N.; Baas, M.; Mühlfeld, E.; de Dreu, C.K.W.; van Gaal, S.

Critical to creative cognition and performance is both the generation of multiple alternative solutions in response to open-ended problems (divergent thinking) and a series of cognitive operations that converges on the correct or best possible answer (convergent thinking). Although the neural

Adaptive Suspicious Prevention for Defending DoS Attacks in SDN-Based Convergent Networks

OpenAIRE

Dao, Nhu-Ngoc; Kim, Joongheon; Park, Minho; Cho, Sungrae

2016-01-01

The convergent communication network will play an important role as a single platform to unify heterogeneous networks and integrate emerging technologies and existing legacy networks. Although there have been proposed many feasible solutions, they could not become convergent frameworks since they mainly focused on converting functions between various protocols and interfaces in edge networks, and handling functions for multiple services in core networks, e.g., the Multi-protocol Label Switchi...

THE ROLE OF MULTIPLICITY IN DISK EVOLUTION AND PLANET FORMATION

Energy Technology Data Exchange (ETDEWEB)

Kraus, Adam L. [Institute for Astronomy, University of Hawaii, 2680 Woodlawn Dr., Honolulu, HI 96822 (United States); Ireland, Michael J. [Sydney Institute for Astronomy (SIfA), School of Physics, University of Sydney, NSW 2006 (Australia); Hillenbrand, Lynne A. [California Institute of Technology, Department of Astrophysics, MC 249-17, Pasadena, CA 91125 (United States); Martinache, Frantz [National Astronomical Observatory of Japan, Subaru Telescope, Hilo, HI 96720 (United States)

2012-01-20

The past decade has seen a revolution in our understanding of protoplanetary disk evolution and planet formation in single-star systems. However, the majority of solar-type stars form in binary systems, so the impact of binary companions on protoplanetary disks is an important element in our understanding of planet formation. We have compiled a combined multiplicity/disk census of Taurus-Auriga, plus a restricted sample of close binaries in other regions, in order to explore the role of multiplicity in disk evolution. Our results imply that the tidal influence of a close ({approx}<40 AU) binary companion significantly hastens the process of protoplanetary disk dispersal, as {approx}2/3 of all close binaries promptly disperse their disks within {approx}<1 Myr after formation. However, prompt disk dispersal only occurs for a small fraction of wide binaries and single stars, with {approx}80%-90% retaining their disks for at least {approx}2-3 Myr (but rarely for more than {approx}5 Myr). Our new constraints on the disk clearing timescale have significant implications for giant planet formation; most single stars have 3-5 Myr within which to form giant planets, whereas most close binary systems would have to form giant planets within {approx}<1 Myr. If core accretion is the primary mode for giant planet formation, then gas giants in close binaries should be rare. Conversely, since almost all single stars have a similar period of time within which to form gas giants, their relative rarity in radial velocity (RV) surveys indicates either that the giant planet formation timescale is very well matched to the disk dispersal timescale or that features beyond the disk lifetime set the likelihood of giant planet formation.

Sustainability and Convergence: The Future of Corporate Governance Systems?

Directory of Open Access Journals (Sweden)

Daniela M. Salvioni

2016-11-01

Full Text Available In today’s world, a sustainable approach to corporate governance can be a source of competitive advantage and a long-term success factor for any firm. Sustainable governance requires that the board of directors considers economic, social and environmental expectations in an integrated way, no matter what ownership structure and formal rules of corporate governance apply to the company: this mitigates the traditional differences between insider and outsider systems of corporate governance. Previous studies failed to consider the contribution of sustainability in the process of corporate governance convergence. Therefore, the aim of this article is to fill the gap in the existing literature by means of a qualitative analysis, supporting the international debate about convergence of corporate governance systems. The article describes the evolution of outsider and insider systems in the light of the increasing importance of sustainability in the board’s decision-making and firm’s operation to satisfy the needs of all the company’s stakeholders. According to this, a qualitative content analysis developed with a directed approach completes the theoretical discussion, demonstrating that sustainability can bring de facto convergence between outsider and insider corporate governance systems. The article aims to be a theoretical starting point for future research, the findings of which could also have practical implications: the study encourages the policy makers to translate the sustainable business best practices into laws and recommendations, strengthening the mutual influence between formal and substantial convergence.

Convergence: How Nursing Unions and Magnet are Advancing Nursing.

Science.gov (United States)

Johnson, Joyce E; Billingsley, Molley

2014-01-01

Historically, unions and professional associations such as the American Nurses Association have been adversaries in the fight to represent the best interests of the nursing profession. We reviewed the literature on the evolution of nursing unions, nursing's historical unease about unions, the Magnet designation in nursing, the tensions between the unions and Magnet, the core values and commonalities they share, and the obligations of nursing as a profession. Refocusing on the advancement of our profession provides a positive pathway in which the collective efforts of nursing unions and professional initiatives such as the Magnet designation converge during these turbulent times for our profession. The single, central organizing idea of nursing-where nursing unions and Magnet converge-is the pivotal role of nurses in delivering high-quality patient care. The often-maligned dialectic between unions and Magnet has advanced and not hindered the nursing profession. © 2014 Wiley Periodicals, Inc.

Convergent Evolution of Pathogen Effectors toward Reactive Oxygen Species Signaling Networks in Plants.

Science.gov (United States)

Jwa, Nam-Soo; Hwang, Byung Kook

2017-01-01

Microbial pathogens have evolved protein effectors to promote virulence and cause disease in host plants. Pathogen effectors delivered into plant cells suppress plant immune responses and modulate host metabolism to support the infection processes of pathogens. Reactive oxygen species (ROS) act as cellular signaling molecules to trigger plant immune responses, such as pathogen-associated molecular pattern (PAMP)-triggered immunity (PTI) and effector-triggered immunity. In this review, we discuss recent insights into the molecular functions of pathogen effectors that target multiple steps in the ROS signaling pathway in plants. The perception of PAMPs by pattern recognition receptors leads to the rapid and strong production of ROS through activation of NADPH oxidase Respiratory Burst Oxidase Homologs (RBOHs) as well as peroxidases. Specific pathogen effectors directly or indirectly interact with plant nucleotide-binding leucine-rich repeat receptors to induce ROS production and the hypersensitive response in plant cells. By contrast, virulent pathogens possess effectors capable of suppressing plant ROS bursts in different ways during infection. PAMP-triggered ROS bursts are suppressed by pathogen effectors that target mitogen-activated protein kinase cascades. Moreover, pathogen effectors target vesicle trafficking or metabolic priming, leading to the suppression of ROS production. Secreted pathogen effectors block the metabolic coenzyme NADP-malic enzyme, inhibiting the transfer of electrons to the NADPH oxidases (RBOHs) responsible for ROS generation. Collectively, pathogen effectors may have evolved to converge on a common host protein network to suppress the common plant immune system, including the ROS burst and cell death response in plants.

Convergent Evolution of Pathogen Effectors toward Reactive Oxygen Species Signaling Networks in Plants

Directory of Open Access Journals (Sweden)

Nam-Soo Jwa

2017-09-01

Full Text Available Microbial pathogens have evolved protein effectors to promote virulence and cause disease in host plants. Pathogen effectors delivered into plant cells suppress plant immune responses and modulate host metabolism to support the infection processes of pathogens. Reactive oxygen species (ROS act as cellular signaling molecules to trigger plant immune responses, such as pathogen-associated molecular pattern (PAMP-triggered immunity (PTI and effector-triggered immunity. In this review, we discuss recent insights into the molecular functions of pathogen effectors that target multiple steps in the ROS signaling pathway in plants. The perception of PAMPs by pattern recognition receptors leads to the rapid and strong production of ROS through activation of NADPH oxidase Respiratory Burst Oxidase Homologs (RBOHs as well as peroxidases. Specific pathogen effectors directly or indirectly interact with plant nucleotide-binding leucine-rich repeat receptors to induce ROS production and the hypersensitive response in plant cells. By contrast, virulent pathogens possess effectors capable of suppressing plant ROS bursts in different ways during infection. PAMP-triggered ROS bursts are suppressed by pathogen effectors that target mitogen-activated protein kinase cascades. Moreover, pathogen effectors target vesicle trafficking or metabolic priming, leading to the suppression of ROS production. Secreted pathogen effectors block the metabolic coenzyme NADP-malic enzyme, inhibiting the transfer of electrons to the NADPH oxidases (RBOHs responsible for ROS generation. Collectively, pathogen effectors may have evolved to converge on a common host protein network to suppress the common plant immune system, including the ROS burst and cell death response in plants.

"Pseudo-Beijing": evidence for convergent evolution in the direct repeat region of Mycobacterium tuberculosis.

Directory of Open Access Journals (Sweden)

Lukas Fenner

Full Text Available Mycobacterium tuberculosis has a global population structure consisting of six main phylogenetic lineages associated with specific geographic regions and human populations. One particular M. tuberculosis genotype known as "Beijing" has repeatedly been associated with drug resistance and has been emerging in some parts of the world. "Beijing" strains are traditionally defined based on a characteristic spoligotyping pattern. We used three alternative genotyping techniques to revisit the phylogenetic classification of M. tuberculosis complex (MTBC strains exhibiting the typical "Beijing" spoligotyping pattern.MTBC strains were obtained from an ongoing molecular epidemiological study in Switzerland and Nepal. MTBC genotyping was performed based on SNPs, genomic deletions, and 24-loci MIRU-VNTR. We identified three MTBC strains from patients originating from Tibet, Portugal and Nepal which exhibited a spoligotyping patterns identical to the classical Beijing signature. However, based on three alternative molecular markers, these strains were assigned to Lineage 3 (also known as Delhi/CAS rather than to Lineage 2 (also known as East-Asian lineage. Sequencing of the RD207 in one of these strains showed that the deletion responsible for this "Pseudo-Beijing" spoligotype was about 1,000 base pairs smaller than the usual deletion of RD207 in classical "Beijing" strains, which is consistent with an evolutionarily independent deletion event in the direct repeat (DR region of MTBC.We provide an example of convergent evolution in the DR locus of MTBC, and highlight the limitation of using spoligotypes for strain classification. Our results indicate that a proportion of "Beijing" strains may have been misclassified in the past. Markers that are more phylogenetically robust should be used when exploring strain-specific differences in experimental or clinical phenotypes.

Local Convergence and Radius of Convergence for Modified Newton Method

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Măruşter Ştefan

2017-12-01

Full Text Available We investigate the local convergence of modified Newton method, i.e., the classical Newton method in which the derivative is periodically re-evaluated. Based on the convergence properties of Picard iteration for demicontractive mappings, we give an algorithm to estimate the local radius of convergence for considered method. Numerical experiments show that the proposed algorithm gives estimated radii which are very close to or even equal with the best ones.

A Dome-Headed Stem Archosaur Exemplifies Convergence among Dinosaurs and Their Distant Relatives.

Science.gov (United States)

Stocker, Michelle R; Nesbitt, Sterling J; Criswell, Katharine E; Parker, William G; Witmer, Lawrence M; Rowe, Timothy B; Ridgely, Ryan; Brown, Matthew A

2016-10-10

Similarities in body plan evolution, such as wings in pterosaurs, birds, and bats or limblessness in snakes and amphisbaenians, can be recognized as classical examples of convergence among animals [1-3]. We introduce a new Triassic stem archosaur that is unexpectedly and remarkably convergent with the "dome-headed" pachycephalosaur dinosaurs that lived over 100 million years later. Surprisingly, numerous additional taxa in the same assemblage (the Otis Chalk assemblage from the Dockum Group of Texas) demonstrate the early acquisition of morphological novelties that were later convergently evolved by post-Triassic dinosaurs. As one of the most successful clades of terrestrial vertebrates, dinosaurs came to occupy an extensive morphospace throughout their diversification in the Mesozoic Era [4, 5], but their distant relatives were first to evolve many of those "dinosaurian" body plans in the Triassic Period [6-8]. Our analysis of convergence between archosauromorphs from the Triassic Period and post-Triassic archosaurs demonstrates the early and extensive exploration of morphospace captured in a single Late Triassic assemblage, and we hypothesize that many of the "novel" morphotypes interpreted to occur among archosaurs later in the Mesozoic already were in place during the initial Triassic archosauromorph, largely non-dinosaurian, radiation and only later convergently evolved in diverse dinosaurian lineages. Copyright © 2016 Elsevier Ltd. All rights reserved.

Intrathecal baclofen in multiple sclerosis and spinal cord injury: complications and long-term dosage evolution.

Science.gov (United States)

Draulans, Nathalie; Vermeersch, Kristof; Degraeuwe, Bart; Meurrens, Tom; Peers, Koen; Nuttin, Bart; Kiekens, Carlotte

2013-12-01

To investigate the long-term dosage evolution and complication rate of intrathecal baclofen use in multiple sclerosis and spinal cord injury patients, based on a large population with a long follow-up. Retrospective data analysis. Academic hospital. Patients with multiple sclerosis (n = 81) or spinal cord injury (n = 49) having an intrathecal baclofen pump implanted at the University Hospitals Leuven between 1988 and 2009. Medical records review of included patients in August 2010. Complications linked to intrathecal baclofen therapy. Daily baclofen dosage after 3 and 6 months, and yearly thereafter. Data on dosage evolution were analysed using a mixed-effect linear model. In 130 patients with a mean follow-up of 63 months, comprising 797 pump years, 104 complications were recorded. This corresponds to a complication rate of 0.011 per month, equally divided among both groups. Seventy-eight of these complications were catheter related. The mean dosage of baclofen stabilizes two years after implantation at 323 µg/day in the multiple sclerosis population. In spinal cord injury patients the daily dose only stabilizes after five years at a significantly higher dosage (504 µg/day). No significant increase in dosage is seen in the long term. In multiple sclerosis and spinal cord injury patients, intrathecal baclofen therapy has a complication rate of 1% per month. Complications are mainly due to catheter-related problems (74%). The intrathecal baclofen dosage stabilizes in the long term, indicating that long-term tolerance, defined as progressive diminution of the susceptibility to the effects of a drug, is not present.

Convergent transcriptional specializations in the brains of humans and song-learning birds

DEFF Research Database (Denmark)

Pfenning, Andreas R.; Hara, Erina; Whitney, Osceola

2014-01-01

Song-learning birds and humans share independently evolved similarities in brain pathways for vocal learning that are essential for song and speech and are not found in most other species. Comparisons of brain transcriptomes of song-learning birds and humans relative to vocal nonlearners identified...... convergent gene expression specializations in specific song and speech brain regions of avian vocal learners and humans. The strongest shared profiles relate bird motor and striatal song-learning nuclei, respectively, with human laryngeal motor cortex and parts of the striatum that control speech production...... and learning. Most of the associated genes function in motor control and brain connectivity. Thus, convergent behavior and neural connectivity for a complex trait are associated with convergent specialized expression of multiple genes....

A Hybrid Backtracking Search Optimization Algorithm with Differential Evolution

Directory of Open Access Journals (Sweden)

Lijin Wang

2015-01-01

Full Text Available The backtracking search optimization algorithm (BSA is a new nature-inspired method which possesses a memory to take advantage of experiences gained from previous generation to guide the population to the global optimum. BSA is capable of solving multimodal problems, but it slowly converges and poorly exploits solution. The differential evolution (DE algorithm is a robust evolutionary algorithm and has a fast convergence speed in the case of exploitive mutation strategies that utilize the information of the best solution found so far. In this paper, we propose a hybrid backtracking search optimization algorithm with differential evolution, called HBD. In HBD, DE with exploitive strategy is used to accelerate the convergence by optimizing one worse individual according to its probability at each iteration process. A suit of 28 benchmark functions are employed to verify the performance of HBD, and the results show the improvement in effectiveness and efficiency of hybridization of BSA and DE.

WRF simulation of a severe hailstorm over Baramati: a study into the space-time evolution

Science.gov (United States)

Murthy, B. S.; Latha, R.; Madhuparna, H.

2018-04-01

Space-time evolution of a severe hailstorm occurred over the western India as revealed by WRF-ARW simulations are presented. We simulated a specific event centered over Baramati (18.15°N, 74.58°E, 537 m AMSL) on March 9, 2014. A physical mechanism, proposed as a conceptual model, signifies the role of multiple convective cells organizing through outflows leading to a cold frontal type flow, in the presence of a low over the northern Arabian Sea, propagates from NW to SE triggering deep convection and precipitation. A `U' shaped cold pool encircled by a converging boundary forms to the north of Baramati due to precipitation behind the moisture convergence line with strong updrafts ( 15 ms-1) leading to convective clouds extending up to 8 km in a narrow region of 30 km. The outflows from the convective clouds merge with the opposing southerly or southwesterly winds from the Arabian Sea and southerly or southeasterly winds from the Bay of Bengal resulting in moisture convergence (maximum 80 × 10-3 g kg-1 s-1). The vertical profile of the area-averaged moisture convergence over the cold pool shows strong convergence above 850 hPa and divergence near the surface indicating elevated convection. Radar reflectivity (50-60 dBZ) and vertical component of vorticity maximum ( 0.01-0.14 s-1) are observed along the convergence zone. Stratiform clouds ahead of the squall line and parallel wind flow at 850 hPa and nearly perpendicular flow at higher levels relative to squall line as evidenced by relatively low and wide-spread reflectivity suggests that organizational mode of squall line may be categorized as `Mixed Mode' type where northern part can be a parallel stratiform while the southern part resembles with a leading stratiform. Simulated rainfall (grid scale 27 km) leads the observed rainfall by 1 h while its magnitude is 2 times of the observed rainfall (grid scale 100 km) derived from Kalpana-1. Thus, this study indicates that under synoptically favorable conditions

Formation and Initiation of Erupting Flux Rope and Embedded Filament Driven by Photospheric Converging Motion

Energy Technology Data Exchange (ETDEWEB)

Zhao Xiaozhou; Gan, Weiqun [Key Laboratory of Dark Matter and Space Astronomy, Purple Mountain Observatory, Chinese Academy of Sciences, 210008 Nanjing (China); Xia, Chun; Keppens, Rony, E-mail: zhaoxz@pmo.ac.cn, E-mail: wqgan@pmo.ac.cn, E-mail: chun.xia@kuleuven.be, E-mail: rony.keppens@kuleuven.be [Centre for mathematical Plasma Astrophysics, Department of Mathematics, KU Leuven, Celestijnenlaan 200B, 3001 Leuven (Belgium)

2017-06-01

In this paper, we study how a flux rope (FR) is formed and evolves into the corresponding structure of a coronal mass ejection (CME) numerically driven by photospheric converging motion. A two-and-a-half-dimensional magnetohydrodynamics simulation is conducted in a chromosphere-transition-corona setup. The initial arcade-like linear force-free magnetic field is driven by an imposed slow motion converging toward the magnetic inversion line at the bottom boundary. The convergence brings opposite-polarity magnetic flux to the polarity inversion, giving rise to the formation of an FR by magnetic reconnection and eventually to the eruption of a CME. During the FR formation, an embedded prominence gets formed by the levitation of chromospheric material. We confirm that the converging flow is a potential mechanism for the formation of FRs and a possible triggering mechanism for CMEs. We investigate the thermal, dynamical, and magnetic properties of the FR and its embedded prominence by tracking their thermal evolution, analyzing their force balance, and measuring their kinematic quantities. The phase transition from the initiation phase to the acceleration phase of the kinematic evolution of the FR was observed in our simulation. The FR undergoes a series of quasi-static equilibrium states in the initiation phase; while in the acceleration phase the FR is driven by Lorentz force and the impulsive acceleration occurs. The underlying physical reason for the phase transition is the change of the reconnection mechanism from the Sweet–Parker to the unsteady bursty regime of reconnection in the evolving current sheet underneath the FR.

The Analysis of the Real Convergence of the Countries from Central and Eastern Europe

Directory of Open Access Journals (Sweden)

Roxana Badircea

2016-11-01

Full Text Available This thesis treats extremely present aspects regarding the evolutions of the emerging economies within the new member states of the European Union insisting on the analysis of the convergence process from a real perspective. Beside the achievement of a monetary union, one of the fundamental objectives of the European Union is represented by the reducing of the disparities regarding the level of development among the member states. One of the ways of appreciating the reduction of the disparities between the economies involve a reduction of the gap as far as the GDP level/inhabitant is concerned or in other words, a real convergence. A series of statistic data are analysed in order to point out the extent to which the central ad East-European states have managed to reduce the gap in report to the developed member states of the EMU, using indicators for the appreciation of the real convergence: the GDP per inhabitant, the monthly average salary, the poverty rate, the contribution of the main sectors of the economy in the formation of the GDP and the unemployment rate. From the analysis of the statistic data one can observe that the highest degree of real convergence is held by Slovenia, which distanced a lot from the other EEC states, followed by the Czech Republic. Regarding from the point of view of the evolution of the EEC countries during the entire analysed period, based on the dynamics of the indicators and of the speed of catching up the gaps we can also notice the performance of the Baltic countries. Unfortunately, Romania and Bulgaria are way behind the other EEC countries.

IT Convergence and Security 2012

CERN Document Server

Chung, Kyung-Yong

2013-01-01

The proceedings approaches the subject matter with problems in technical convergence and convergences of security technology. This approach is new because we look at new issues that arise from techniques converging. The general scope of the proceedings content is convergence security and the latest information technology. The intended readership are societies, enterprises, and research institutes, and intended content level is mid- to highly educated personals. The most important features and benefits of the proceedings are the introduction of the most recent information technology and its related ideas, applications and problems related to technology convergence, and its case studies and finally an introduction of converging existing security techniques through convergence security. Overall, through the proceedings, authors will be able to understand the most state of the art information strategies and technologies of convergence security.

Modified Spectral Projected Subgradient Method: Convergence Analysis and Momentum Parameter Heuristics

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Milagros Loreto

2016-09-01

Full Text Available The Modified Spectral Projected Subgradient (MSPS was proposed to solve Langrangen Dual Problems, and its convergence was shown when the momentum term was zero. The MSPS uses a momentum term in order to speed up its convergence. The momentum term is built on the multiplication of a momentum parameter and the direction of the previous iterate. In this work, we show convergence when the momentum parameter is a non-zero constant. We also propose heuristics to choose the momentum parameter intended to avoid the Zigzagging Phenomenon of Kind I. This phenomenon is present in the MSPS when at an iterate the subgradient forms an obtuse angle with the previous direction. We identify and diminish the Zigzagging Phenomenon of Kind I on Setcovering problems, and compare our numerical results to those of the original MSPS algorithm.

Media Convergence: the Culture Dimensions of Thinking%Media Convergence:the Culture Dimensions of Thinking

Institute of Scientific and Technical Information of China (English)

Shen Diao; Lan Ju

2017-01-01

In the process of meida Convergence,many researchers paid excessive attention to media technology,industry and management,and ignored the culture dimensions of media convergence.Therefore,to transcend media convergence technology,industrial thinking and more to the particularity attach importance to cultural media,it is a right way to achieve media convergence.But in the context of China's culture,media convergence should value the cultural uniqueness and the imbalance of the realistic problems,to reach innovation and breakthrough.

Understanding Spatiotemporal Patterns of Human Convergence and Divergence Using Mobile Phone Location Data

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Xiping Yang

2016-09-01

Full Text Available Investigating human mobility patterns can help researchers and agencies understand the driving forces of human movement, with potential benefits for urban planning and traffic management. Recent advances in location-aware technologies have provided many new data sources (e.g., mobile phone and social media data for studying human space-time behavioral regularity. Although existing studies have utilized these new datasets to characterize human mobility patterns from various aspects, such as predicting human mobility and monitoring urban dynamics, few studies have focused on human convergence and divergence patterns within a city. This study aims to explore human spatial convergence and divergence and their evolutions over time using large-scale mobile phone location data. Using a dataset from Shenzhen, China, we developed a method to identify spatiotemporal patterns of human convergence and divergence. Eight distinct patterns were extracted, and the spatial distributions of these patterns are discussed in the context of urban functional regions. Thus, this study investigates urban human convergence and divergence patterns and their relationships with the urban functional environment, which is helpful for urban policy development, urban planning and traffic management.

Almost convergence of triple sequences

OpenAIRE

Ayhan Esi; M.Necdet Catalbas

2013-01-01

In this paper we introduce and study the concepts of almost convergence and almost Cauchy for triple sequences. Weshow that the set of almost convergent triple sequences of 0's and 1's is of the first category and also almost everytriple sequence of 0's and 1's is not almost convergent.Keywords: almost convergence, P-convergent, triple sequence.

Convergence among cave catfishes: long-branch attraction and a Bayesian relative rates test.

Science.gov (United States)

Wilcox, T P; García de León, F J; Hendrickson, D A; Hillis, D M

2004-06-01

Convergence has long been of interest to evolutionary biologists. Cave organisms appear to be ideal candidates for studying convergence in morphological, physiological, and developmental traits. Here we report apparent convergence in two cave-catfishes that were described on morphological grounds as congeners: Prietella phreatophila and Prietella lundbergi. We collected mitochondrial DNA sequence data from 10 species of catfishes, representing five of the seven genera in Ictaluridae, as well as seven species from a broad range of siluriform outgroups. Analysis of the sequence data under parsimony supports a monophyletic Prietella. However, both maximum-likelihood and Bayesian analyses support polyphyly of the genus, with P. lundbergi sister to Ictalurus and P. phreatophila sister to Ameiurus. The topological difference between parsimony and the other methods appears to result from long-branch attraction between the Prietella species. Similarly, the sequence data do not support several other relationships within Ictaluridae supported by morphology. We develop a new Bayesian method for examining variation in molecular rates of evolution across a phylogeny.

Societal response to nanotechnology: converging technologies–converging societal response research?

NARCIS (Netherlands)

Ronteltap, A.; Fischer, A.R.H.; Tobi, H.

2011-01-01

Nanotechnology is an emerging technology particularly vulnerable to societal unrest, which may hinder its further development. With the increasing convergence of several technological domains in the field of nanotechnology, so too could convergence of social science methods help to anticipate

Exploring Media Convergence: Evidence from Italy

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Debora Bettiga

2013-12-01

Full Text Available The evolution of media and devices is enabling the ubiquitous and multi-device access to media and information, so that a media mutual contamination is in play. New forms of user interactions with media, in which different devices are used simultaneously in different contexts, have emerged. These new interactions are significantly impacting on users’ attitudes towards the media and their way of searching and generating content. Such a change, called “media convergence”, has a strong potential impact on marketing and communication processes, but as yet has not been deeply analysed in the literature. This paper presents the outcomes of several studies aimed at exploring media convergence on the demand-side to advance possible implications for marketers and managers.

Mixed-time parallel evolution in multiple quantum NMR experiments: sensitivity and resolution enhancement in heteronuclear NMR

International Nuclear Information System (INIS)

Ying Jinfa; Chill, Jordan H.; Louis, John M.; Bax, Ad

2007-01-01

A new strategy is demonstrated that simultaneously enhances sensitivity and resolution in three- or higher-dimensional heteronuclear multiple quantum NMR experiments. The approach, referred to as mixed-time parallel evolution (MT-PARE), utilizes evolution of chemical shifts of the spins participating in the multiple quantum coherence in parallel, thereby reducing signal losses relative to sequential evolution. The signal in a given PARE dimension, t 1 , is of a non-decaying constant-time nature for a duration that depends on the length of t 2 , and vice versa, prior to the onset of conventional exponential decay. Line shape simulations for the 1 H- 15 N PARE indicate that this strategy significantly enhances both sensitivity and resolution in the indirect 1 H dimension, and that the unusual signal decay profile results in acceptable line shapes. Incorporation of the MT-PARE approach into a 3D HMQC-NOESY experiment for measurement of H N -H N NOEs in KcsA in SDS micelles at 50 o C was found to increase the experimental sensitivity by a factor of 1.7±0.3 with a concomitant resolution increase in the indirectly detected 1 H dimension. The method is also demonstrated for a situation in which homonuclear 13 C- 13 C decoupling is required while measuring weak H3'-2'OH NOEs in an RNA oligomer

Acceleration of criticality analysis solution convergence by matrix eigenvector for a system with weak neutron interaction

Energy Technology Data Exchange (ETDEWEB)

Nomura, Yasushi; Takada, Tomoyuki; Kuroishi, Takeshi [Japan Atomic Energy Research Inst., Tokai, Ibaraki (Japan). Tokai Research Establishment; Kadotani, Hiroyuki [Shizuoka Sangyo Univ., Iwata, Shizuoka (Japan)

2003-03-01

In the case of Monte Carlo calculation to obtain a neutron multiplication factor for a system of weak neutron interaction, there might be some problems concerning convergence of the solution. Concerning this difficulty in the computer code calculations, theoretical derivation was made from the general neutron transport equation and consideration was given for acceleration of solution convergence by using the matrix eigenvector in this report. Accordingly, matrix eigenvector calculation scheme was incorporated together with procedure to make acceleration of convergence into the continuous energy Monte Carlo code MCNP. Furthermore, effectiveness of acceleration of solution convergence by matrix eigenvector was ascertained with the results obtained by applying to the two OECD/NEA criticality analysis benchmark problems. (author)

Summable series and convergence factors

CERN Document Server

Moore, Charles N

1938-01-01

Fairly early in the development of the theory of summability of divergent series, the concept of convergence factors was recognized as of fundamental importance in the subject. One of the pioneers in this field was C. N. Moore, the author of the book under review.... Moore classifies convergence factors into two types. In type I he places the factors which have only the property that they preserve convergence for a convergent series or produce convergence for a summable series. In type II he places the factors which not only maintain or produce convergence but have the additional property that

Converging on the Initial Mass Function of Stars

International Nuclear Information System (INIS)

Federrath, Christoph; Krumholz, Mark; Hopkins, Philip F.

2017-01-01

Understanding the origin of stellar masses—the initial mass function (IMF)— remains one of the most challenging problems in astrophysics. The IMF is a key ingredient for simulations of galaxy formation and evolution, and is used to calibrate star formation relations in extra-galactic observations. Modeling the IMF directly in hydrodynamical simulations has been attempted in several previous studies, but the most important processes that control the IMF remain poorly understood. This is because predicting the IMF from direct hydrodynamical simulations involves complex physics such as turbulence, magnetic fields, radiation feedback and mechanical feedback, all of which are difficult to model and the methods used have limitations in terms of accuracy and computational efficiency. Moreover, a physical interpretation of the simulated IMFs requires a numerically converged solution at high resolution, which has so far not been convincingly demonstrated. Here we present a resolution study of star cluster formation aimed at producing a converged IMF. We compare a set of magnetohydrodynamical (MHD) adaptive-mesh-refinement simulations with three different implementations of the thermodynamics of the gas: 1) with an isothermal equation of state (EOS), 2) with a polytropic EOS, and 3) with a simple stellar heating feedback model. We show that in the simulations with an isothermal or polytropic EOS, the number of stars and their mass distributions depend on the numerical resolution. By contrast, the simulations that employ the simple radiative feedback module demonstrate convergence in the number of stars formed and in their IMFs. (paper)

Optimizing Transmission Network Expansion Planning With The Mean Of Chaotic Differential Evolution Algorithm

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Ahmed R. Abdelaziz

2015-08-01

Full Text Available This paper presents an application of Chaotic differential evolution optimization approach meta-heuristics in solving transmission network expansion planning TNEP using an AC model associated with reactive power planning RPP. The reliabilityredundancy of network analysis optimization problems implicate selection of components with multiple choices and redundancy levels that produce maximum benefits can be subject to the cost weight and volume constraints is presented in this paper. Classical mathematical methods have failed in handling non-convexities and non-smoothness in optimization problems. As an alternative to the classical optimization approaches the meta-heuristics have attracted lot of attention due to their ability to find an almost global optimal solution in reliabilityredundancy optimization problems. Evolutionary algorithms EAs paradigms of evolutionary computation field are stochastic and robust meta-heuristics useful to solve reliabilityredundancy optimization problems. EAs such as genetic algorithm evolutionary programming evolution strategies and differential evolution are being used to find global or near global optimal solution. The Differential Evolution Algorithm DEA population-based algorithm is an optimal algorithm with powerful global searching capability but it is usually in low convergence speed and presents bad searching capability in the later evolution stage. A new Chaotic Differential Evolution algorithm CDE based on the cat map is recommended which combines DE and chaotic searching algorithm. Simulation results and comparisons show that the chaotic differential evolution algorithm using Cat map is competitive and stable in performance with other optimization approaches and other maps.

Evolution of the Converged NGN Service Platforms Towards Future Networks

NARCIS (Netherlands)

Mikóczy, E.; Kotuliak, I.; Deventer, M.O. van

2011-01-01

This article presents a comparison of main characteristics of the Next Generation Networks (NGN) and Future Generation Internet (FGI). The aim is to discuss and compare two approaches to Future Networks (FN) and services: the evolution of NGN, and the revolutionary approach of a new FGI. We present

Convergent and invariant object representations for sight, sound, and touch.

Science.gov (United States)

Man, Kingson; Damasio, Antonio; Meyer, Kaspar; Kaplan, Jonas T

2015-09-01

We continuously perceive objects in the world through multiple sensory channels. In this study, we investigated the convergence of information from different sensory streams within the cerebral cortex. We presented volunteers with three common objects via three different modalities-sight, sound, and touch-and used multivariate pattern analysis of functional magnetic resonance imaging data to map the cortical regions containing information about the identity of the objects. We could reliably predict which of the three stimuli a subject had seen, heard, or touched from the pattern of neural activity in the corresponding early sensory cortices. Intramodal classification was also successful in large portions of the cerebral cortex beyond the primary areas, with multiple regions showing convergence of information from two or all three modalities. Using crossmodal classification, we also searched for brain regions that would represent objects in a similar fashion across different modalities of presentation. We trained a classifier to distinguish objects presented in one modality and then tested it on the same objects presented in a different modality. We detected audiovisual invariance in the right temporo-occipital junction, audiotactile invariance in the left postcentral gyrus and parietal operculum, and visuotactile invariance in the right postcentral and supramarginal gyri. Our maps of multisensory convergence and crossmodal generalization reveal the underlying organization of the association cortices, and may be related to the neural basis for mental concepts. © 2015 Wiley Periodicals, Inc.

The Evolution of Agriculture in Insects

DEFF Research Database (Denmark)

Mueller, Ulrich G.; Gerardo, Nicole M.; Aanen, Duur Kornelis

2005-01-01

Agriculture has evolved independently in three insect orders: once in ants, once in termites, and seven times in ambrosia beetles. Although these insect farmers are in some ways quite different from each other, in many more ways they are remarkably similar, suggesting convergent evolution. All pr...

Constraint shapes convergence in tetrodotoxin-resistant sodium channels of snakes.

Science.gov (United States)

Feldman, Chris R; Brodie, Edmund D; Brodie, Edmund D; Pfrender, Michael E

2012-03-20

Natural selection often produces convergent changes in unrelated lineages, but the degree to which such adaptations occur via predictable genetic paths is unknown. If only a limited subset of possible mutations is fixed in independent lineages, then it is clear that constraint in the production or function of molecular variants is an important determinant of adaptation. We demonstrate remarkably constrained convergence during the evolution of resistance to the lethal poison, tetrodotoxin, in six snake species representing three distinct lineages from around the globe. Resistance-conferring amino acid substitutions in a voltage-gated sodium channel, Na(v)1.4, are clustered in only two regions of the protein, and a majority of the replacements are confined to the same three positions. The observed changes represent only a small fraction of the experimentally validated mutations known to increase Na(v)1.4 resistance to tetrodotoxin. These results suggest that constraints resulting from functional tradeoffs between ion channel function and toxin resistance led to predictable patterns of evolutionary convergence at the molecular level. Our data are consistent with theoretical predictions and recent microcosm work that suggest a predictable path is followed during an adaptive walk along a mutational landscape, and that natural selection may be frequently constrained to produce similar genetic outcomes even when operating on independent lineages.

Bilingualism and Creativity: Benefits in Convergent Thinking Come with Losses in Divergent Thinking

Science.gov (United States)

Hommel, Bernhard; Colzato, Lorenza S.; Fischer, Rico; Christoffels, Ingrid K.

2011-01-01

Bilingualism is commonly assumed to improve creativity but the mechanisms underlying creative acts, and the way these mechanisms are affected by bilingualism, are not very well understood. We hypothesize that learning to master multiple languages drives individuals toward a relatively focused cognitive-control state that exerts strong top-down impact on information processing and creates strong local competition for selection between cognitive codes. Considering the control requirements posed by creativity tasks tapping into convergent and divergent thinking, this predicts that high-proficient bilinguals should outperform low-proficient bilinguals in convergent thinking, while low-proficient bilinguals might be better in divergent thinking. Comparing low- and high-proficient bilinguals on convergent-thinking and divergent-thinking tasks indeed showed a high-proficient bilingual advantage for convergent thinking but a low-proficient bilingual advantage for fluency in divergent thinking. These findings suggest that bilingualism should not be related to “creativity” as a unitary concept but, rather, to the specific processes and mechanisms that underlie creativity. PMID:22084634

Bilingualism and creativity: Benefits in convergent thinking come with losses in divergent thinking

Directory of Open Access Journals (Sweden)

Bernhard eHommel

2011-11-01

Full Text Available Bilingualism is commonly assumed to improve creativity but the mechanisms underlying creative acts, and the way these mechanisms are affected by bilingualism, are not very well understood. We hypothesize that learning to master multiple languages drives individuals towards a strongly focused cognitive-control state that exerts strong top-down impact on information processing and creates strong local competition for selection between cognitive codes. Considering the control requirements posed by creativity tasks tapping into convergent and divergent thinking, this predicts that high-proficient bilinguals should outperform low-proficient bilinguals in convergent thinking, while low-proficient bilinguals might be better in divergent thinking. Comparing low- and high-proficient bilinguals on convergent-thinking and divergent-thinking tasks indeed showed a high-proficient bilingual advantage for convergent thinking but a low-proficient bilingual advantage for fluency in divergent thinking. These findings suggest that bilingualism should not be related to creativity as a unitary concept but, rather, to the specific processes and mechanisms that underlie creativity.

Allopatric diversification, multiple habitat shifts, and hybridization in the evolution of Pericallis (Asteraceae), a Macaronesian endemic genus.

Science.gov (United States)

Jones, Katy E; Reyes-Betancort, J Alfredo; Hiscock, Simon J; Carine, Mark A

2014-04-01

Geographic isolation, habitat shifts, and hybridization have contributed to the diversification of oceanic island floras. We investigated the contribution of these processes to the diversification of Pericallis, a genus endemic to Macaronesia. Data from the chloroplast psaI-accD and trnV-ndhC regions and the nuclear ribosomal internal transcribed spacer region (ITS) were sampled for multiple accessions of all taxa and used to establish phylogenetic hypotheses. Habitat preferences were optimized to investigate habitat shifts, and divergence times were estimated. Species nonmonophyly was investigated using Bayes factors. Much of the diversification in Pericallis has occurred recently, within the past 1.7 Ma. Three habitat shifts have occurred in the evolution of the genus. However, geographic isolation has played a greater role in its diversification. Novel allopatric patterns were revealed within some species, highlighting the significance of geographic isolation in the evolution of Pericallis. One species (P. appendiculata) that resolved as monophyletic in the ITS analysis was polyphyletic in the chloroplast analysis. Bayes factors provide strong support for the nonmonophyly of P. appendiculata haplotypes, and their phylogenetic placement suggests that ancient hybridization is responsible for the haplotype diversity observed. Multiple markers and extensive sampling provided new insights into the evolution of Pericallis. In contrast to previous studies, our results reveal a more significant role for allopatry than habitat shifts and new evidence for ancient hybridization in the evolution of Pericallis. Our study highlights the power of broad taxon sampling for unraveling diversity patterns and processes within oceanic island radiations.

Multiple sulfur isotopes monitor fluid evolution of an Archean orogenic gold deposit

Science.gov (United States)

LaFlamme, Crystal; Sugiono, Dennis; Thébaud, Nicolas; Caruso, Stefano; Fiorentini, Marco; Selvaraja, Vikraman; Jeon, Heejin; Voute, François; Martin, Laure

2018-02-01

The evolution of a gold-bearing hydrothermal fluid from its source to the locus of gold deposition is complex as it experiences rapid changes in thermochemical conditions during ascent through the crust. Although it is well established that orogenic gold deposits are generated during time periods of abundant crustal growth and/or reworking, the source of fluid and the thermochemical processes that control gold precipitation remain poorly understood. In situ analyses of multiple sulfur isotopes offer a new window into the relationship between source reservoirs of Au-bearing fluids and the thermochemical processes that occur along their pathway to the final site of mineralisation. Whereas δ34S is able to track changes in the evolution of the thermodynamic conditions of ore-forming fluids, Δ33S is virtually indelible and can uniquely fingerprint an Archean sedimentary reservoir that has undergone mass independent fractionation of sulfur (MIF-S). We combine these two tracers (δ34S and Δ33S) to characterise a gold-bearing laminated quartz breccia ore zone and its sulfide-bearing alteration halo in the (+6 Moz Au) structurally-controlled Archean Waroonga deposit located in the Eastern Goldfields Superterrane of the Yilgarn Craton, Western Australia. Over 250 analyses of gold-associated sulfides yield a δ34S shift from what is interpreted as an early pre-mineralisation phase, with chalcopyrite-pyrrhotite (δ34S = +0.7‰ to +2.9‰) and arsenopyrite cores (δ34S = ∼-0.5‰), to a syn-mineralisation stage, reflected in Au-bearing arsenopyrite rims (δ34S = -7.6‰ to +1.5‰). This shift coincides with an unchanging Δ33S value (Δ33S = +0.3‰), both temporally throughout the Au-hosting hydrothermal sulfide paragenesis and spatially across the Au ore zone. These results indicate that sulfur is at least partially recycled from MIF-S-bearing Archean sediments. Further, the invariant nature of the observed MIF-S signature demonstrates that sulfur is derived from a

The ecological and genetic basis of convergent thick-lipped phenotypes in cichlid fishes.

Science.gov (United States)

Colombo, Marco; Diepeveen, Eveline T; Muschick, Moritz; Santos, M Emilia; Indermaur, Adrian; Boileau, Nicolas; Barluenga, Marta; Salzburger, Walter

2013-02-01

The evolution of convergent phenotypes is one of the most interesting outcomes of replicate adaptive radiations. Remarkable cases of convergence involve the thick-lipped phenotype found across cichlid species flocks in the East African Great Lakes. Unlike most other convergent forms in cichlids, which are restricted to East Africa, the thick-lipped phenotype also occurs elsewhere, for example in the Central American Midas Cichlid assemblage. Here, we use an ecological genomic approach to study the function, the evolution and the genetic basis of this phenotype in two independent cichlid adaptive radiations on two continents. We applied phylogenetic, demographic, geometric morphometric and stomach content analyses to an African (Lobochilotes labiatus) and a Central American (Amphilophus labiatus) thick-lipped species. We found that similar morphological adaptations occur in both thick-lipped species and that the 'fleshy' lips are associated with hard-shelled prey in the form of molluscs and invertebrates. We then used comparative Illumina RNA sequencing of thick vs. normal lip tissue in East African cichlids and identified a set of 141 candidate genes that appear to be involved in the morphogenesis of this trait. A more detailed analysis of six of these genes led to three strong candidates: Actb, Cldn7 and Copb. The function of these genes can be linked to the loose connective tissue constituting the fleshy lips. Similar trends in gene expression between African and Central American thick-lipped species appear to indicate that an overlapping set of genes was independently recruited to build this particular phenotype in both lineages. © 2012 Blackwell Publishing Ltd.

The converged Sn algorithm for nuclear criticality

International Nuclear Information System (INIS)

Ganapol, B. D.; Hadad, K.

2009-01-01

A new discrete ordinates algorithm to determine the multiplication factor of a 1D nuclear reactor, based on Bengt Carlson's S n method, is presented. The algorithm applies the Romberg and Wynn-epsilon accelerators to accelerate a 1D, one-group S n solution to its asymptotic limit. We demonstrate the feasibility of the Converged Sn (CSn) solution on several one-group criticality benchmark compilations. The new formulation is especially convenient since it enables highly accurate critical fluxes and eigenvalues using the most fundamental transport algorithm. (authors)

Convergence analysis of household expenditures using the absolute β-convergence method

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Anto Domazet

2012-01-01

Full Text Available Background: The paper examines the convergence of household expenditures, in terms of a possible usage of the standardized, rather than consumer-tailored marketing, mainly on a regional level. Objectives: The main goal of this research is to study the existence of consumption expenditure convergence in the EU-27 countries, in the period between 2000 and 2007. Methods/Approach: The analysis used the absolute β-convergence method, in order to investigate the existence of a negative correlation between the growth over time in the overall consumption expenditure in EU member- countries for each individual product and service category and the initial expenditure level. Results: According to the obtained results, in the period between 2000 and 2007, the EU-27 countries reached a high level of consumer expenditure convergence, which provides a basis for developing a regional concept of the standardized international marketing for these countries’ markets. Conclusions: The results provide an empirical contribution to claims on consumer convergence in the countries included into economic integrations. Also, the obtained results can be used to create a basis for defining and applying the regional marketing concept for companies focusing on the EU-27 countries’ market.

Systematic Analysis Reveals that Cancer Mutations Converge on Deregulated Metabolism of Arachidonate and Xenobiotics

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Francesco Gatto

2016-07-01

Full Text Available Mutations are the basis of the clonal evolution of most cancers. Nevertheless, a systematic analysis of whether mutations are selected in cancer because they lead to the deregulation of specific biological processes independent of the type of cancer is still lacking. In this study, we correlated the genome and transcriptome of 1,082 tumors. We found that nine commonly mutated genes correlated with substantial changes in gene expression, which primarily converged on metabolism. Further network analyses circumscribed the convergence to a network of reactions, termed AraX, that involves the glutathione- and oxygen-mediated metabolism of arachidonic acid and xenobiotics. In an independent cohort of 4,462 samples, all nine mutated genes were consistently correlated with the deregulation of AraX. Among all of the metabolic pathways, AraX deregulation represented the strongest predictor of patient survival. These findings suggest that oncogenic mutations drive a selection process that converges on the deregulation of the AraX network.

The expression and evolution of virulence in multiple infections: the role of specificity, relative virulence and relative dose.

Science.gov (United States)

Ben-Ami, Frida; Routtu, Jarkko

2013-05-03

Multiple infections of the same host by different strains of the same microparasite species are believed to play a crucial role during the evolution of parasite virulence. We investigated the role of specificity, relative virulence and relative dose in determining the competitive outcome of multiple infections in the Daphnia magna-Pasteuria ramosa host-parasite system. We found that infections by P. ramosa clones (single genotype) were less virulent and produced more spores than infections by P. ramosa isolates (possibly containing multiple genotypes). We also found that two similarly virulent isolates of P. ramosa differed considerably in their within-host competitiveness and their effects on host offspring production when faced with coinfecting P. ramosa isolates and clones. Although the relative virulence of a P. ramosa isolate/clone appears to be a good indicator of its competitiveness during multiple infections, the relative dose may alter the competitive outcome. Moreover, spore counts on day 20 post-infection indicate that the competitive outcome is largely decided early in the parasite's growth phase, possibly mediated by direct interference or apparent competition. Our results emphasize the importance of epidemiology as well as of various parasite traits in determining the outcome of within-host competition. Incorporating realistic epidemiological and ecological conditions when testing theoretical models of multiple infections, as well as using a wider range of host and parasite genotypes, will enable us to better understand the course of virulence evolution.

Reliability-redundancy optimization by means of a chaotic differential evolution approach

International Nuclear Information System (INIS)

Coelho, Leandro dos Santos

2009-01-01

The reliability design is related to the performance analysis of many engineering systems. The reliability-redundancy optimization problems involve selection of components with multiple choices and redundancy levels that produce maximum benefits, can be subject to the cost, weight, and volume constraints. Classical mathematical methods have failed in handling nonconvexities and nonsmoothness in optimization problems. As an alternative to the classical optimization approaches, the meta-heuristics have been given much attention by many researchers due to their ability to find an almost global optimal solution in reliability-redundancy optimization problems. Evolutionary algorithms (EAs) - paradigms of evolutionary computation field - are stochastic and robust meta-heuristics useful to solve reliability-redundancy optimization problems. EAs such as genetic algorithm, evolutionary programming, evolution strategies and differential evolution are being used to find global or near global optimal solution. A differential evolution approach based on chaotic sequences using Lozi's map for reliability-redundancy optimization problems is proposed in this paper. The proposed method has a fast convergence rate but also maintains the diversity of the population so as to escape from local optima. An application example in reliability-redundancy optimization based on the overspeed protection system of a gas turbine is given to show its usefulness and efficiency. Simulation results show that the application of deterministic chaotic sequences instead of random sequences is a possible strategy to improve the performance of differential evolution.

Transformation and diversification in early mammal evolution.

Science.gov (United States)

Luo, Zhe-Xi

2007-12-13

Evolution of the earliest mammals shows successive episodes of diversification. Lineage-splitting in Mesozoic mammals is coupled with many independent evolutionary experiments and ecological specializations. Classic scenarios of mammalian morphological evolution tend to posit an orderly acquisition of key evolutionary innovations leading to adaptive diversification, but newly discovered fossils show that evolution of such key characters as the middle ear and the tribosphenic teeth is far more labile among Mesozoic mammals. Successive diversifications of Mesozoic mammal groups multiplied the opportunities for many dead-end lineages to iteratively evolve developmental homoplasies and convergent ecological specializations, parallel to those in modern mammal groups.

Cultura da Convergência

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Rogério Christofoletti

2008-12-01

Full Text Available Three ideas would suffice for the reading of “Cultura da Convergência” (Culture of Convergence by Henry Jenkins to be of interest to journalists and researchers in the area: media convergence as a cultural process; the strengthening of an emotional economy which guides consumers of symbolic goods and media creators; the expansion of trans-media narrative forms.

Cultura da Convergência

Directory of Open Access Journals (Sweden)

Rogério Christofoletti

2011-02-01

Full Text Available Three ideas would suffice for the reading of “Cultura da Convergência” (Culture of Convergence by Henry Jenkins to be of interest to journalists and researchers in the area: media convergence as a cultural process; the strengthening of an emotional economy which guides consumers of symbolic goods and media creators; the expansion of trans-media narrative forms.

Robust Monotonically Convergent Iterative Learning Control for Discrete-Time Systems via Generalized KYP Lemma

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Jian Ding

2014-01-01

Full Text Available This paper addresses the problem of P-type iterative learning control for a class of multiple-input multiple-output linear discrete-time systems, whose aim is to develop robust monotonically convergent control law design over a finite frequency range. It is shown that the 2 D iterative learning control processes can be taken as 1 D state space model regardless of relative degree. With the generalized Kalman-Yakubovich-Popov lemma applied, it is feasible to describe the monotonically convergent conditions with the help of linear matrix inequality technique and to develop formulas for the control gain matrices design. An extension to robust control law design against systems with structured and polytopic-type uncertainties is also considered. Two numerical examples are provided to validate the feasibility and effectiveness of the proposed method.

A bivariate Chebyshev spectral collocation quasilinearization method for nonlinear evolution parabolic equations.

Science.gov (United States)

Motsa, S S; Magagula, V M; Sibanda, P

2014-01-01

This paper presents a new method for solving higher order nonlinear evolution partial differential equations (NPDEs). The method combines quasilinearisation, the Chebyshev spectral collocation method, and bivariate Lagrange interpolation. In this paper, we use the method to solve several nonlinear evolution equations, such as the modified KdV-Burgers equation, highly nonlinear modified KdV equation, Fisher's equation, Burgers-Fisher equation, Burgers-Huxley equation, and the Fitzhugh-Nagumo equation. The results are compared with known exact analytical solutions from literature to confirm accuracy, convergence, and effectiveness of the method. There is congruence between the numerical results and the exact solutions to a high order of accuracy. Tables were generated to present the order of accuracy of the method; convergence graphs to verify convergence of the method and error graphs are presented to show the excellent agreement between the results from this study and the known results from literature.

A Bivariate Chebyshev Spectral Collocation Quasilinearization Method for Nonlinear Evolution Parabolic Equations

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S. S. Motsa

2014-01-01

Full Text Available This paper presents a new method for solving higher order nonlinear evolution partial differential equations (NPDEs. The method combines quasilinearisation, the Chebyshev spectral collocation method, and bivariate Lagrange interpolation. In this paper, we use the method to solve several nonlinear evolution equations, such as the modified KdV-Burgers equation, highly nonlinear modified KdV equation, Fisher's equation, Burgers-Fisher equation, Burgers-Huxley equation, and the Fitzhugh-Nagumo equation. The results are compared with known exact analytical solutions from literature to confirm accuracy, convergence, and effectiveness of the method. There is congruence between the numerical results and the exact solutions to a high order of accuracy. Tables were generated to present the order of accuracy of the method; convergence graphs to verify convergence of the method and error graphs are presented to show the excellent agreement between the results from this study and the known results from literature.

Parameter identification based on modified simulated annealing differential evolution algorithm for giant magnetostrictive actuator

Science.gov (United States)

Gao, Xiaohui; Liu, Yongguang

2018-01-01

There is a serious nonlinear relationship between input and output in the giant magnetostrictive actuator (GMA) and how to establish mathematical model and identify its parameters is very important to study characteristics and improve control accuracy. The current-displacement model is firstly built based on Jiles-Atherton (J-A) model theory, Ampere loop theorem and stress-magnetism coupling model. And then laws between unknown parameters and hysteresis loops are studied to determine the data-taking scope. The modified simulated annealing differential evolution algorithm (MSADEA) is proposed by taking full advantage of differential evolution algorithm's fast convergence and simulated annealing algorithm's jumping property to enhance the convergence speed and performance. Simulation and experiment results shows that this algorithm is not only simple and efficient, but also has fast convergence speed and high identification accuracy.

The long road to convergence and back. Convergence and crossmedia journalism at Dutch Newsmedia

NARCIS (Netherlands)

Tameling, Klaske; Broersma, Marcel

2012-01-01

KLASKE TAMELING & MARCEL BROERSMA The long road to convergence and back. Convergence and crossmedia journalism at Dutch Newsmedia Since the end of the twentieth century, convergence and cross-media journalism are concepts that are widely used to guide the future of journalism world wide. This study

Mutualistic interactions drive ecological niche convergence in a diverse butterfly community.

Science.gov (United States)

Elias, Marianne; Gompert, Zachariah; Jiggins, Chris; Willmott, Keith

2008-12-02

Ecological communities are structured in part by evolutionary interactions among their members. A number of recent studies incorporating phylogenetics into community ecology have upheld the paradigm that competition drives ecological divergence among species of the same guild. However, the role of other interspecific interactions, in particular positive interactions such as mutualism, remains poorly explored. We characterized the ecological niche and inferred phylogenetic relationships among members of a diverse community of neotropical Müllerian mimetic butterflies. Müllerian mimicry is one of the best studied examples of mutualism, in which unpalatable species converge in wing pattern locally to advertize their toxicity to predators. We provide evidence that mutualistic interactions can drive convergence along multiple ecological axes, outweighing both phylogeny and competition in shaping community structure. Our findings imply that ecological communities are adaptively assembled to a much greater degree than commonly suspected. In addition, our results show that phenotype and ecology are strongly linked and support the idea that mimicry can cause ecological speciation through multiple cascading effects on species' biology.

Mutualistic interactions drive ecological niche convergence in a diverse butterfly community.

Directory of Open Access Journals (Sweden)

Marianne Elias

2008-12-01

Full Text Available Ecological communities are structured in part by evolutionary interactions among their members. A number of recent studies incorporating phylogenetics into community ecology have upheld the paradigm that competition drives ecological divergence among species of the same guild. However, the role of other interspecific interactions, in particular positive interactions such as mutualism, remains poorly explored. We characterized the ecological niche and inferred phylogenetic relationships among members of a diverse community of neotropical Müllerian mimetic butterflies. Müllerian mimicry is one of the best studied examples of mutualism, in which unpalatable species converge in wing pattern locally to advertize their toxicity to predators. We provide evidence that mutualistic interactions can drive convergence along multiple ecological axes, outweighing both phylogeny and competition in shaping community structure. Our findings imply that ecological communities are adaptively assembled to a much greater degree than commonly suspected. In addition, our results show that phenotype and ecology are strongly linked and support the idea that mimicry can cause ecological speciation through multiple cascading effects on species' biology.

Convergent Metabolic Specialization through Distinct Evolutionary Paths in Pseudomonas aeruginosa

DEFF Research Database (Denmark)

La Rosa, Ruggero; Johansen, Helle Krogh; Molin, Søren

2018-01-01

fibrosis (CF) infection. In this work, we investigated how and through which trajectories evolution of Pseudomonas aeruginosa occurs when migrating from the environment to the airways of CF patients, and specifically, we determined reduction of growth rate and metabolic specialization as signatures...... of adaptive evolution. We show that central metabolic pathways of three distinct Pseudomonas aeruginosa lineages coevolving within the same environment become restructured at the cost of versatility during long-term colonization. Cell physiology changes from naive to adapted phenotypes resulted in (i......) alteration of growth potential that particularly converged to a slow-growth phenotype, (ii) alteration of nutritional requirements due to auxotrophy, (iii) tailored preference for carbon source assimilation from CF sputum, (iv) reduced arginine and pyruvate fermentation processes, and (v) increased oxygen...

Societal response to nanotechnology: converging technologies–converging societal response research?

International Nuclear Information System (INIS)

Ronteltap, Amber; Fischer, Arnout R. H.; Tobi, Hilde

2011-01-01

Nanotechnology is an emerging technology particularly vulnerable to societal unrest, which may hinder its further development. With the increasing convergence of several technological domains in the field of nanotechnology, so too could convergence of social science methods help to anticipate societal response. This paper systematically reviews the current state of convergence in societal response research by first sketching the predominant approaches to previous new technologies, followed by an analysis of current research into societal response to nanotechnology. A set of 107 papers on previous new technologies shows that rational actor models have played an important role in the study of societal response to technology, in particular in the field of information technology and the geographic region of Asia. Biotechnology and nuclear power have, in contrast, more often been investigated through risk perception and other affective determinants, particularly in Europe and the USA. A set of 42 papers on societal response to nanotechnology shows similarities to research in biotechnology, as it also builds on affective variables such as risk perception. Although there is a tendency to extend the rational models with affective variables, convergence in social science approaches to response to new technologies still has a long way to go. The challenge for researchers of societal response to technologies is to converge to some shared principles by taking up the best parts from the rational actor models dominant in information technology, whilst integrating non-rational constructs from biotechnology research. The introduction of nanotechnology gives a unique opportunity to do so.

Converging evolution leads to near maximal junction diversity through parallel mechanisms in B and T cell receptors

Science.gov (United States)

Benichou, Jennifer I. C.; van Heijst, Jeroen W. J.; Glanville, Jacob; Louzoun, Yoram

2017-08-01

T and B cell receptor (TCR and BCR) complementarity determining region 3 (CDR3) genetic diversity is produced through multiple diversification and selection stages. Potential holes in the CDR3 repertoire were argued to be linked to immunodeficiencies and diseases. In contrast with BCRs, TCRs have practically no Dβ germline genetic diversity, and the question emerges as to whether they can produce a diverse CDR3 repertoire. In order to address the genetic diversity of the adaptive immune system, appropriate quantitative measures for diversity and large-scale sequencing are required. Such a diversity method should incorporate the complex diversification mechanisms of the adaptive immune response and the BCR and TCR loci structure. We combined large-scale sequencing and diversity measures to show that TCRs have a near maximal CDR3 genetic diversity. Specifically, TCR have a larger junctional and V germline diversity, which starts more 5‧ in Vβ than BCRs. Selection decreases the TCR repertoire diversity, but does not affect BCR repertoire. As a result, TCR is as diverse as BCR repertoire, with a biased CDR3 length toward short TCRs and long BCRs. These differences suggest parallel converging evolutionary tracks to reach the required diversity to avoid holes in the CDR3 repertoire.

Applying Convergent Immunity to Innovative Vaccines Targeting Staphylococcus aureus

Science.gov (United States)

Yeaman, Michael R.; Filler, Scott G.; Schmidt, Clint S.; Ibrahim, Ashraf S.; Edwards, John E.; Hennessey, John P.

2014-01-01

Recent perspectives forecast a new paradigm for future “third generation” vaccines based on commonalities found in diverse pathogens or convergent immune defenses to such pathogens. For Staphylococcus aureus, recurring infections and a limited success of vaccines containing S. aureus antigens imply that native antigens induce immune responses insufficient for optimal efficacy. These perspectives exemplify the need to apply novel vaccine strategies to high-priority pathogens. One such approach can be termed convergent immunity, where antigens from non-target organisms that contain epitope homologs found in the target organism are applied in vaccines. This approach aims to evoke atypical immune defenses via synergistic processes that (1) afford protective efficacy; (2) target an epitope from one organism that contributes to protective immunity against another; (3) cross-protect against multiple pathogens occupying a common anatomic or immunological niche; and/or (4) overcome immune subversion or avoidance strategies of target pathogens. Thus, convergent immunity has a potential to promote protective efficacy not usually elicited by native antigens from a target pathogen. Variations of this concept have been mainstays in the history of viral and bacterial vaccine development. A more far-reaching example is the pre-clinical evidence that specific fungal antigens can induce cross-kingdom protection against bacterial pathogens. This trans-kingdom protection has been demonstrated in pre-clinical studies of the recombinant Candida albicans agglutinin-like sequence 3 protein (rAls3) where it was shown that a vaccine containing rAls3 provides homologous protection against C. albicans, heterologous protection against several other Candida species, and convergent protection against several strains of S. aureus. Convergent immunity reflects an intriguing new approach to designing and developing vaccine antigens and is considered here in the context of vaccines to target S

Applying Convergent Immunity to Innovative Vaccines Targeting Staphylococcus aureus

Directory of Open Access Journals (Sweden)

Michael R Yeaman

2014-09-01

Full Text Available Recent perspectives forecast a new paradigm for future 3rd generation vaccines based on commonalities found in diverse pathogens or convergent immune defenses to such pathogens. For Staphylococcus aureus, recurring infections and a limited success of vaccines containing S. aureus antigens imply that native antigens induce immune responses insufficient for optimal efficacy. These perspectives exemplify the need to apply novel vaccine strategies to high priority pathogens. One such approach can be termed convergent immunity, where antigens from non-target organisms that contain epitope homologues found in the target organism are applied in vaccines. This approach aims to evoke atypical immune defenses via synergistic processes that 1 afford protective efficacy; 2 target an epitope from one organism that contributes to protective immunity against another; 3 cross-protect against multiple pathogens occupying a common anatomic or immunologic niche; and/or 4 overcome immune subversion or avoidance strategies of target pathogens. Thus, convergent immunity has a potential to promote protective efficacy not usually elicited by native antigens from a target pathogen. Variations of this concept have been mainstays in the history of viral and bacterial vaccine development. A more far-reaching example is the pre–clinical evidence that specific fungal antigens can induce cross-kingdom protection against bacterial pathogens. This trans-kingdom protection has been demonstrated in preclinical studies of the recombinant Candida albicans agglutinin-like sequence 3 protein (rAls3 where it was shown that a vaccine containing rAls3 provides homologous protection against C. albicans, heterologous protection against several other Candida species, and convergent protection against several strains of S. aureus. Convergent immunity reflects an intriguing new approach to designing and developing vaccine antigens and is considered here in the context of vaccines to target

Convergence of Nelson diffusions

International Nuclear Information System (INIS)

Dell'Antonio, G.; Posilicano, A.

1991-01-01

Let ψ t , ψ t n , n≥1, be solutions of Schroedinger equations with potentials form-bounded by -1/2 Δ and initial data in H 1 (R d ). Let P, P n , n≥1, be the probability measures on the path space Ω=C(R + , R d ) given by the corresponding Nelson diffusions. We show that if {ψ t n } n≥1 converges to ψ t in H 2 (R d ), uniformly in t over compact intervals, then {P n } n≥1 converges to P in total variation. Moreover, if the potentials are in the Kato class K d , we show that the above result follows from H 1 -convergence of initial data, and K d -convergence of potentials. (orig.)

CONVERGENCE AND DIVERGENCE IN EUROPEAN UNION: EVIDENCE FOR BETA CONVERGENCE AMONG NEW EU MEMBER STATES

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Ioana Sorina Mihuț

2013-07-01

Full Text Available Abstract: Convergence may be considered a central issue of the current economic literature, and not only, concentrating upon income distribution within different economies, but also focusing on different aspects of polarity and inequality that characterize especially the emerging economies. Testing convergence within economies may serve as a useful instrument for the validation of the economic growth models. While convergence was considered a defining element of the neoclassical growth models, the majority of the new endogenous growth models argue in favour of divergence across different economies. Testing convergence among European Union is even more challenging due to the high degree of heterogeneity that characterizes these economies. The recent accessions with ten new countries in 2004 and with another two in 2007 were considered only the first step towards assuring a sustainable convergence and finally adopting a common currency-the euro. A series of empirical studies concentrated upon testing convergence among EU, using as benchmark the real convergence quantified by the level of GDP/capita as an indicator for the living standards of every economy. The most popular approach rely on Beta and Sigma convergence, the first one being and indicator of the GDP/capita dispersion between different economies, and the later one being an estimator of the reverse relationship between GDP/capita and its initial level. The main purpose of this paper is to test Beta converge among the new EU member states, in order to obtained more information about the fact whether the poor countries are trying to catch-up with the more developed one. Also Beta convergence indicator embodies useful information about conditional and un-conditional convergence, two leading hypothesis within the neoclassical and endogenous growth models. For Beta convergence hypothesis to be valid it should be taken into consideration a ”catch-up” mechanism over a longer period of time

Evolution of Anolis lizard dewlap diversity.

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Kirsten E Nicholson

Full Text Available BACKGROUND: The dewlaps of Anolis lizards provide a classic example of a complex signaling system whose function and evolution is poorly understood. Dewlaps are flaps of skin beneath the chin that are extended and combined with head and body movements for visual signals and displays. They exhibit extensive morphological variation and are one of two cladistic features uniting anoles, yet little is known regarding their function and evolution. We quantified the diversity of anole dewlaps, investigated whether dewlap morphology was informative regarding phylogenetic relationships, and tested two separate hypotheses: (A similar Anolis habitat specialists possess similar dewlap configurations (Ecomorph Convergence hypothesis, and (B sympatric species differ in their dewlap morphologies to a greater extent than expected by chance (Species Recognition hypothesis. METHODOLOGY/PRINCIPAL FINDINGS: We found that dewlap configurations (sizes, patterns and colors exhibit substantial diversity, but that most are easily categorized into six patterns that incorporate one to three of 13 recognizable colors. Dewlap morphology is not phylogenetically informative and, like other features of anoles, exhibits convergence in configurations. We found no support for the Ecomorph Convergence hypothesis; species using the same structural habitat were no more similar in dewlap configuration than expected by chance. With one exception, all sympatric species in four communities differ in dewlap configuration. However, this provides only weak support for the Species Recognition hypothesis because, due to the great diversity in dewlap configurations observed across each island, few cases of sympatric species with identical dewlaps would be expected to co-occur by chance alone. CONCLUSIONS/SIGNIFICANCE: Despite previous thought, most dewlaps exhibit easily characterizable patterns and colorations. Nevertheless, dewlap variation is extensive and explanations for the origin and

Statistical evaluation of the degree of nominal convergence of the inflation rate in Romania

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Mihai GHEORGHE

2011-07-01

Full Text Available Nominal convergence is a process that is characterised by the gradual harmonisation, to a relatively high degree, of the national institutions and policies of the Member States with those of the EU, in the monetary and financial fields.The birth of nominal convergence is marked by the Maastricht Treaty, by means of which the criteria required for adopting the euro were established. One of the criteria refers to price stability (inflation rate, which is measured by the Harmonised Index of Consumer Prices. A Member State meets this criterion if it has a price performance that is sustainable and an average rate of inflation, observed over a period of one year before the examination,that does not exceed by more than 1.5 percentage point that of, at most, the three best performing Member States in terms of price stability.The article proposes a model for the statistical evaluation of the degree to which the nominal convergence criterion related to price stability is met. The evaluation is based on the following pillars: a theoretical synthesis of the Harmonised Index of Consumer Prices, a statistical analysis concerning the evolution of inflation in Romania and the gap vis-à-vis the reference value for meeting the nominal convergence criterion.

Evolutionary conservatism and convergence both lead to striking similarity in ecology, morphology and performance across continents in frogs.

Science.gov (United States)

Moen, Daniel S; Irschick, Duncan J; Wiens, John J

2013-12-22

Many clades contain ecologically and phenotypically similar species across continents, yet the processes generating this similarity are largely unstudied, leaving fundamental questions unanswered. Is similarity in morphology and performance across assemblages caused by evolutionary convergence or by biogeographic dispersal of evolutionarily conserved ecotypes? Does convergence to new ecological conditions erase evidence of past adaptation? Here, we analyse ecology, morphology and performance in frog assemblages from three continents (Asia, Australia and South America), assessing the importance of dispersal and convergent evolution in explaining similarity across regions. We find three striking results. First, species using the same microhabitat type are highly similar in morphology and performance across both clades and continents. Second, some species on different continents owe their similarity to dispersal and evolutionary conservatism (rather than evolutionary convergence), even over vast temporal and spatial scales. Third, in one case, an ecologically specialized ancestor radiated into diverse ecotypes that have converged with those on other continents, largely erasing traces of past adaptation to their ancestral ecology. Overall, our study highlights the roles of both evolutionary conservatism and convergence in explaining similarity in species traits over large spatial and temporal scales and demonstrates a statistical framework for addressing these questions in other systems.

Stable convergence and stable limit theorems

CERN Document Server

Häusler, Erich

2015-01-01

The authors present a concise but complete exposition of the mathematical theory of stable convergence and give various applications in different areas of probability theory and mathematical statistics to illustrate the usefulness of this concept. Stable convergence holds in many limit theorems of probability theory and statistics – such as the classical central limit theorem – which are usually formulated in terms of convergence in distribution. Originated by Alfred Rényi, the notion of stable convergence is stronger than the classical weak convergence of probability measures. A variety of methods is described which can be used to establish this stronger stable convergence in many limit theorems which were originally formulated only in terms of weak convergence. Naturally, these stronger limit theorems have new and stronger consequences which should not be missed by neglecting the notion of stable convergence. The presentation will be accessible to researchers and advanced students at the master's level...

The Great Silk Alternative: Multiple Co-Evolution of Web Loss and Sticky Hairs in Spiders

Science.gov (United States)

Wolff, Jonas O.; Nentwig, Wolfgang; Gorb, Stanislav N.

2013-01-01

Spiders are the most important terrestrial predators among arthropods. Their ecological success is reflected by a high biodiversity and the conquest of nearly every terrestrial habitat. Spiders are closely associated with silk, a material, often seen to be responsible for their great ecological success and gaining high attention in life sciences. However, it is often overlooked that more than half of all Recent spider species have abandoned web building or never developed such an adaptation. These species must have found other, more economic solutions for prey capture and retention, compensating the higher energy costs of increased locomotion activity. Here we show that hairy adhesive pads (scopulae) are closely associated with the convergent evolution of a vagrant life style, resulting in highly diversified lineages of at least, equal importance as the derived web building taxa. Previous studies often highlighted the idea that scopulae have the primary function of assisting locomotion, neglecting the fact that only the distal most pads (claw tufts) are suitable for those purposes. The former observations, that scopulae are used in prey capture, are largely overlooked. Our results suggest the scopulae evolved as a substitute for silk in controlling prey and that the claw tufts are, in most cases, a secondary development. Evolutionary trends towards specialized claw tufts and their composition from a low number of enlarged setae to a dense array of slender ones, as well as the secondary loss of those pads are discussed further. Hypotheses about the origin of the adhesive setae and their diversification throughout evolution are provided. PMID:23650526

On the Convergence in Effective Loop Quantum Cosmology

International Nuclear Information System (INIS)

Corichi, Alejandro; Vukasinac, Tatjana; Zapata, Jose Antonio

2010-01-01

In Loop Quantum Cosmology (LQC) there is a discreteness parameter λ, that has been heuristically associated to a fundamental granularity of quantum geometry. It is also possible to consider λ as a regulator in the same spirit as that used in lattice field theory, where it specifies a regular lattice in the real line. A particular quantization of the k = 0 FLRW loop cosmological model yields a completely solvable model, known as solvable loop quantum cosmology(sLQC). In this contribution, we consider effective classical theories motivated by sLQC and study their λ-dependence, with a special interest on the limit λ→0 and the role of the evolution parameter in the convergence of such limit.

Convergent differential regulation of parvalbumin in the brains of vocal learners.

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Erina Hara

Full Text Available Spoken language and learned song are complex communication behaviors found in only a few species, including humans and three groups of distantly related birds--songbirds, parrots, and hummingbirds. Despite their large phylogenetic distances, these vocal learners show convergent behaviors and associated brain pathways for vocal communication. However, it is not clear whether this behavioral and anatomical convergence is associated with molecular convergence. Here we used oligo microarrays to screen for genes differentially regulated in brain nuclei necessary for producing learned vocalizations relative to adjacent brain areas that control other behaviors in avian vocal learners versus vocal non-learners. A top candidate gene in our screen was a calcium-binding protein, parvalbumin (PV. In situ hybridization verification revealed that PV was expressed significantly higher throughout the song motor pathway, including brainstem vocal motor neurons relative to the surrounding brain regions of all distantly related avian vocal learners. This differential expression was specific to PV and vocal learners, as it was not found in avian vocal non-learners nor for control genes in learners and non-learners. Similar to the vocal learning birds, higher PV up-regulation was found in the brainstem tongue motor neurons used for speech production in humans relative to a non-human primate, macaques. These results suggest repeated convergent evolution of differential PV up-regulation in the brains of vocal learners separated by more than 65-300 million years from a common ancestor and that the specialized behaviors of learned song and speech may require extra calcium buffering and signaling.

Sensitivity of Optimal Solutions to Control Problems for Second Order Evolution Subdifferential Inclusions.

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Bartosz, Krzysztof; Denkowski, Zdzisław; Kalita, Piotr

In this paper the sensitivity of optimal solutions to control problems described by second order evolution subdifferential inclusions under perturbations of state relations and of cost functionals is investigated. First we establish a new existence result for a class of such inclusions. Then, based on the theory of sequential [Formula: see text]-convergence we recall the abstract scheme concerning convergence of minimal values and minimizers. The abstract scheme works provided we can establish two properties: the Kuratowski convergence of solution sets for the state relations and some complementary [Formula: see text]-convergence of the cost functionals. Then these two properties are implemented in the considered case.

A Meta-Analysis of the Convergent Validity of Self-Control Measures

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Duckworth, Angela Lee; Kern, Margaret L.

2011-01-01

There is extraordinary diversity in how the construct of self-control is operationalized in research studies. We meta-analytically examined evidence of convergent validity among executive function, delay of gratification, and self- and informant-report questionnaire measures of self-control. Overall, measures demonstrated moderate convergence (rrandom = .27 [95% CI = .24, .30]; rfixed = .34 [.33, .35], k = 282 samples, N = 33,564 participants), although there was substantial heterogeneity in the observed correlations. Correlations within and across types of self-control measures were strongest for informant-report questionnaires and weakest for executive function tasks. Questionnaires assessing sensation seeking impulses could be distinguished from questionnaires assessing processes of impulse regulation. We conclude that self-control is a coherent but multidimensional construct best assessed using multiple methods. PMID:21643479

Analysis of convergent gene transcripts in the obligate intracellular bacterium Rickettsia prowazekii.

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Andrew Woodard

2011-01-01

Full Text Available Termination of transcription is an important component of bacterial gene expression. However, little is known concerning this process in the obligate intracellular pathogen and model for reductive evolution, Rickettsia prowazekii. To assess transcriptional termination in this bacterium, transcripts of convergent gene pairs, some containing predicted intrinsic terminators, were analyzed. These analyses revealed that, rather than terminating at a specific site within the intervening region between the convergent genes, most of the transcripts demonstrated either a lack of termination within this region, which generated antisense RNA, or a putative non-site-specific termination that occurred throughout the intervening sequence. Transcripts terminating at predicted intrinsic terminators, as well as at a putative Rho-dependant terminator, were also examined and found to vary based on the rickettsial host environment. These results suggest that transcriptional termination, or lack thereof, plays a role in rickettsial gene regulation.

Evolution of multiple phosphodiesterase isoforms in stickleback involved in cAMP signal transduction pathway.

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Sato, Yukuto; Hashiguchi, Yasuyuki; Nishida, Mutsumi

2009-02-20

Duplicate genes are considered to have evolved through the partitioning of ancestral functions among duplicates (subfunctionalization) and/or the acquisition of novel functions from a beneficial mutation (neofunctionalization). Additionally, an increase in gene dosage resulting from duplication may also confer an advantageous effect, as has been suggested for histone, tRNA, and rRNA genes. Currently, there is little understanding of the effect of increased gene dosage on subcellular networks like signal transduction pathways. Addressing this issue may provide further insights into the evolution by gene duplication. We analyzed the evolution of multiple stickleback phosphodiesterase (PDE, EC: 3.1.4.17) 1C genes involved in the cyclic nucleotide signaling pathway. Stickleback has 8-9 copies of this gene, whereas only one or two loci exist in other model vertebrates. Our phylogenetic and synteny analyses suggested that the multiple PDE1C genes in stickleback were generated by repeated duplications of >100-kbp chromosome segments. Sequence evolution analysis did not provide strong evidence for neofunctionalization in the coding sequences of stickleback PDE1C isoforms. On the other hand, gene expression analysis suggested that the derived isoforms acquired expression in new organs, implying their neofunctionalization in terms of expression patterns. In addition, at least seven isoforms of the stickleback PDE1C were co-expressed with olfactory-type G-proteins in the nose, suggesting that PDE1C dosage is increased in the stickleback olfactory transduction (OT) pathway. In silico simulations of OT implied that the increased PDE1C dosage extends the longevity of the depolarization signals of the olfactory receptor neuron. The predicted effect of the increase in PDE1C products on the OT pathway may play an important role in stickleback behavior and ecology. However, this possibility should be empirically examined. Our analyses imply that an increase in gene product sometimes

Evolution of multiple phosphodiesterase isoforms in stickleback involved in cAMP signal transduction pathway

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Nishida Mutsumi

2009-02-01

Full Text Available Abstract Background Duplicate genes are considered to have evolved through the partitioning of ancestral functions among duplicates (subfunctionalization and/or the acquisition of novel functions from a beneficial mutation (neofunctionalization. Additionally, an increase in gene dosage resulting from duplication may also confer an advantageous effect, as has been suggested for histone, tRNA, and rRNA genes. Currently, there is little understanding of the effect of increased gene dosage on subcellular networks like signal transduction pathways. Addressing this issue may provide further insights into the evolution by gene duplication. Results We analyzed the evolution of multiple stickleback phosphodiesterase (PDE, EC: 3.1.4.17 1C genes involved in the cyclic nucleotide signaling pathway. Stickleback has 8–9 copies of this gene, whereas only one or two loci exist in other model vertebrates. Our phylogenetic and synteny analyses suggested that the multiple PDE1C genes in stickleback were generated by repeated duplications of >100-kbp chromosome segments. Sequence evolution analysis did not provide strong evidence for neofunctionalization in the coding sequences of stickleback PDE1C isoforms. On the other hand, gene expression analysis suggested that the derived isoforms acquired expression in new organs, implying their neofunctionalization in terms of expression patterns. In addition, at least seven isoforms of the stickleback PDE1C were co-expressed with olfactory-type G-proteins in the nose, suggesting that PDE1C dosage is increased in the stickleback olfactory transduction (OT pathway. In silico simulations of OT implied that the increased PDE1C dosage extends the longevity of the depolarization signals of the olfactory receptor neuron. Conclusion The predicted effect of the increase in PDE1C products on the OT pathway may play an important role in stickleback behavior and ecology. However, this possibility should be empirically examined. Our

Evolution families of conformal mappings with fixed points and the Löwner-Kufarev equation

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Goryainov, V V

2015-01-01

The paper is concerned with evolution families of conformal mappings of the unit disc to itself that fix an interior point and a boundary point. Conditions are obtained for the evolution families to be differentiable, and an existence and uniqueness theorem for an evolution equation is proved. A convergence theorem is established which describes the topology of locally uniform convergence of evolution families in terms of infinitesimal generating functions. The main result in this paper is the embedding theorem which shows that any conformal mapping of the unit disc to itself with two fixed points can be embedded into a differentiable evolution family of such mappings. This result extends the range of the parametric method in the theory of univalent functions. In this way the problem of the mutual change of the derivative at an interior point and the angular derivative at a fixed point on the boundary is solved for a class of mappings of the unit disc to itself. In particular, the rotation theorem is established for this class of mappings. Bibliography: 27 titles

Lake Malawi cichlid evolution along a benthic/limnetic axis.

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Hulsey, C D; Roberts, R J; Loh, Y-H E; Rupp, M F; Streelman, J T

2013-07-01

Divergence along a benthic to limnetic habitat axis is ubiquitous in aquatic systems. However, this type of habitat divergence has largely been examined in low diversity, high latitude lake systems. In this study, we examined the importance of benthic and limnetic divergence within the incredibly species-rich radiation of Lake Malawi cichlid fishes. Using novel phylogenetic reconstructions, we provided a series of hypotheses regarding the evolutionary relationships among 24 benthic and limnetic species that suggests divergence along this axis has occurred multiple times within Lake Malawi cichlids. Because pectoral fin morphology is often associated with divergence along this habitat axis in other fish groups, we investigated divergence in pectoral fin muscles in these benthic and limnetic cichlid species. We showed that the eight pectoral fin muscles and fin area generally tended to evolve in a tightly correlated manner in the Lake Malawi cichlids. Additionally, we found that larger pectoral fin muscles are strongly associated with the independent evolution of the benthic feeding habit across this group of fish. Evolutionary specialization along a benthic/limnetic axis has occurred multiple times within this tropical lake radiation and has produced repeated convergent matching between exploitation of water column habitats and locomotory morphology.

Convergence criterion for branched contіnued fractions of the special form with positive elements

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D. I. Bodnar

2017-07-01

Full Text Available In this paper the problem of convergence of the important type of a multidimensional generalization of continued fractions, the branched continued fractions with independent variables, is considered. This fractions are an efficient apparatus for the approximation of multivariable functions, which are represented by multiple power series. When variables are fixed these fractions are called the branched continued fractions of the special form. Their structure is much simpler then the structure of general branched continued fractions. It has given a possibility to establish the necessary and sufficient conditions of convergence of branched continued fractions of the special form with the positive elements. The received result is the multidimensional analog of Seidel's criterion for the continued fractions. The condition of convergence of investigated fractions is the divergence of series, whose elements are continued fractions. Therefore, the sufficient condition of the convergence of this fraction which has been formulated by the divergence of series composed of partial denominators of this fraction, is established. Using the established criterion and Stieltjes-Vitali Theorem the parabolic theorems of branched continued fractions of the special form with complex elements convergence, is investigated. The sufficient conditions gave a possibility to make the condition of convergence of the branched continued fractions of the special form, whose elements lie in parabolic domains.

Genomic and phenotypic characterization of myxoma virus from Great Britain reveals multiple evolutionary pathways distinct from those in Australia.

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Peter J Kerr

2017-03-01

Full Text Available The co-evolution of myxoma virus (MYXV and the European rabbit occurred independently in Australia and Europe from different progenitor viruses. Although this is the canonical study of the evolution of virulence, whether the genomic and phenotypic outcomes of MYXV evolution in Europe mirror those observed in Australia is unknown. We addressed this question using viruses isolated in the United Kingdom early in the MYXV epizootic (1954-1955 and between 2008-2013. The later UK viruses fell into three distinct lineages indicative of a long period of separation and independent evolution. Although rates of evolutionary change were almost identical to those previously described for MYXV in Australia and strongly clock-like, genome evolution in the UK and Australia showed little convergence. The phenotypes of eight UK viruses from three lineages were characterized in laboratory rabbits and compared to the progenitor (release Lausanne strain. Inferred virulence ranged from highly virulent (grade 1 to highly attenuated (grade 5. Two broad disease types were seen: cutaneous nodular myxomatosis characterized by multiple raised secondary cutaneous lesions, or an amyxomatous phenotype with few or no secondary lesions. A novel clinical outcome was acute death with pulmonary oedema and haemorrhage, often associated with bacteria in many tissues but an absence of inflammatory cells. Notably, reading frame disruptions in genes defined as essential for virulence in the progenitor Lausanne strain were compatible with the acquisition of high virulence. Combined, these data support a model of ongoing host-pathogen co-evolution in which multiple genetic pathways can produce successful outcomes in the field that involve both different virulence grades and disease phenotypes, with alterations in tissue tropism and disease mechanisms.

Genomic and phenotypic characterization of myxoma virus from Great Britain reveals multiple evolutionary pathways distinct from those in Australia.

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Kerr, Peter J; Cattadori, Isabella M; Rogers, Matthew B; Fitch, Adam; Geber, Adam; Liu, June; Sim, Derek G; Boag, Brian; Eden, John-Sebastian; Ghedin, Elodie; Read, Andrew F; Holmes, Edward C

2017-03-01

The co-evolution of myxoma virus (MYXV) and the European rabbit occurred independently in Australia and Europe from different progenitor viruses. Although this is the canonical study of the evolution of virulence, whether the genomic and phenotypic outcomes of MYXV evolution in Europe mirror those observed in Australia is unknown. We addressed this question using viruses isolated in the United Kingdom early in the MYXV epizootic (1954-1955) and between 2008-2013. The later UK viruses fell into three distinct lineages indicative of a long period of separation and independent evolution. Although rates of evolutionary change were almost identical to those previously described for MYXV in Australia and strongly clock-like, genome evolution in the UK and Australia showed little convergence. The phenotypes of eight UK viruses from three lineages were characterized in laboratory rabbits and compared to the progenitor (release) Lausanne strain. Inferred virulence ranged from highly virulent (grade 1) to highly attenuated (grade 5). Two broad disease types were seen: cutaneous nodular myxomatosis characterized by multiple raised secondary cutaneous lesions, or an amyxomatous phenotype with few or no secondary lesions. A novel clinical outcome was acute death with pulmonary oedema and haemorrhage, often associated with bacteria in many tissues but an absence of inflammatory cells. Notably, reading frame disruptions in genes defined as essential for virulence in the progenitor Lausanne strain were compatible with the acquisition of high virulence. Combined, these data support a model of ongoing host-pathogen co-evolution in which multiple genetic pathways can produce successful outcomes in the field that involve both different virulence grades and disease phenotypes, with alterations in tissue tropism and disease mechanisms.

Genomic and phenotypic characterization of myxoma virus from Great Britain reveals multiple evolutionary pathways distinct from those in Australia

Science.gov (United States)

Kerr, Peter J.; Cattadori, Isabella M.; Fitch, Adam; Geber, Adam; Liu, June; Sim, Derek G.; Boag, Brian; Ghedin, Elodie

2017-01-01

The co-evolution of myxoma virus (MYXV) and the European rabbit occurred independently in Australia and Europe from different progenitor viruses. Although this is the canonical study of the evolution of virulence, whether the genomic and phenotypic outcomes of MYXV evolution in Europe mirror those observed in Australia is unknown. We addressed this question using viruses isolated in the United Kingdom early in the MYXV epizootic (1954–1955) and between 2008–2013. The later UK viruses fell into three distinct lineages indicative of a long period of separation and independent evolution. Although rates of evolutionary change were almost identical to those previously described for MYXV in Australia and strongly clock-like, genome evolution in the UK and Australia showed little convergence. The phenotypes of eight UK viruses from three lineages were characterized in laboratory rabbits and compared to the progenitor (release) Lausanne strain. Inferred virulence ranged from highly virulent (grade 1) to highly attenuated (grade 5). Two broad disease types were seen: cutaneous nodular myxomatosis characterized by multiple raised secondary cutaneous lesions, or an amyxomatous phenotype with few or no secondary lesions. A novel clinical outcome was acute death with pulmonary oedema and haemorrhage, often associated with bacteria in many tissues but an absence of inflammatory cells. Notably, reading frame disruptions in genes defined as essential for virulence in the progenitor Lausanne strain were compatible with the acquisition of high virulence. Combined, these data support a model of ongoing host-pathogen co-evolution in which multiple genetic pathways can produce successful outcomes in the field that involve both different virulence grades and disease phenotypes, with alterations in tissue tropism and disease mechanisms. PMID:28253375

Evolution of fNL to the adiabatic limit

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Elliston, Joseph; Mulryne, David J.; Seery, David; Tavakol, Reza

2011-11-01

We study inflationary perturbations in multiple-field models, for which ζ typically evolves until all isocurvature modes decay — the "adiabatic limit". We use numerical methods to explore the sensitivity of the local-shape bispectrum to the process by which this limit is achieved, finding an appreciable dependence on model-specific data such as the time at which slow-roll breaks down or the timescale of reheating. In models with a sum-separable potential where the isocurvature modes decay before the end of the slow-roll phase we give an analytic criterion for the asymptotic value of fNL to be large. Other examples can be constructed using a waterfall field to terminate inflation while fNL is transiently large, caused by descent from a ridge or convergence into a valley. We show that these two types of evolution are distinguished by the sign of the bispectrum, and give approximate expressions for the peak fNL.

Evolution of fNL to the adiabatic limit

International Nuclear Information System (INIS)

Elliston, Joseph; Mulryne, David J.; Tavakol, Reza; Seery, David

2011-01-01

We study inflationary perturbations in multiple-field models, for which ζ typically evolves until all isocurvature modes decay — the a diabatic limit . We use numerical methods to explore the sensitivity of the local-shape bispectrum to the process by which this limit is achieved, finding an appreciable dependence on model-specific data such as the time at which slow-roll breaks down or the timescale of reheating. In models with a sum-separable potential where the isocurvature modes decay before the end of the slow-roll phase we give an analytic criterion for the asymptotic value of f NL to be large. Other examples can be constructed using a waterfall field to terminate inflation while f NL is transiently large, caused by descent from a ridge or convergence into a valley. We show that these two types of evolution are distinguished by the sign of the bispectrum, and give approximate expressions for the peak f NL

Convergence from divergence

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Costin, Ovidiu; Dunne, Gerald V.

2018-01-01

We show how to convert divergent series, which typically occur in many applications in physics, into rapidly convergent inverse factorial series. This can be interpreted physically as a novel resummation of perturbative series. Being convergent, these new series allow rigorous extrapolation from an asymptotic region with a large parameter, to the opposite region where the parameter is small. We illustrate the method with various physical examples, and discuss how these convergent series relate to standard methods such as Borel summation, and also how they incorporate the physical Stokes phenomenon. We comment on the relation of these results to Dyson’s physical argument for the divergence of perturbation theory. This approach also leads naturally to a wide class of relations between bosonic and fermionic partition functions, and Klein-Gordon and Dirac determinants.

Convergence of calls as animals form social bonds, active compensation for noisy communication channels, and the evolution of vocal learning in mammals.

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Tyack, Peter L

2008-08-01

The classic evidence for vocal production learning involves imitation of novel, often anthropogenic sounds. Among mammals, this has been reported for dolphins, elephants, harbor seals, and humans. A broader taxonomic distribution has been reported for vocal convergence, where the acoustic properties of calls from different individuals converge when they are housed together in captivity or form social bonds in the wild. Vocal convergence has been demonstrated for animals as diverse as songbirds, parakeets, hummingbirds, bats, elephants, cetaceans, and primates. For most species, call convergence is thought to reflect a group-distinctive identifier, with shared calls reflecting and strengthening social bonds. A ubiquitous function for vocal production learning that is starting to receive attention involves modifying signals to improve communication in a noisy channel. Pooling data on vocal imitation, vocal convergence, and compensation for noise suggests a wider taxonomic distribution of vocal production learning among mammals than has been generally appreciated. The wide taxonomic distribution of this evidence for vocal production learning suggests that perhaps more of the neural underpinnings for vocal production learning are in place in mammals than is usually recognized. (c) 2008 APA, all rights reserved

Density by Moduli and Lacunary Statistical Convergence

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Vinod K. Bhardwaj

2016-01-01

Full Text Available We have introduced and studied a new concept of f-lacunary statistical convergence, where f is an unbounded modulus. It is shown that, under certain conditions on a modulus f, the concepts of lacunary strong convergence with respect to a modulus f and f-lacunary statistical convergence are equivalent on bounded sequences. We further characterize those θ for which Sθf=Sf, where Sθf and Sf denote the sets of all f-lacunary statistically convergent sequences and f-statistically convergent sequences, respectively. A general description of inclusion between two arbitrary lacunary methods of f-statistical convergence is given. Finally, we give an Sθf-analog of the Cauchy criterion for convergence and a Tauberian theorem for Sθf-convergence is also proved.

Evolution based on domain combinations: the case of glutaredoxins

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Herrero Enrique

2009-03-01

Full Text Available Abstract Background Protein domains represent the basic units in the evolution of proteins. Domain duplication and shuffling by recombination and fusion, followed by divergence are the most common mechanisms in this process. Such domain fusion and recombination events are predicted to occur only once for a given multidomain architecture. However, other scenarios may be relevant in the evolution of specific proteins, such as convergent evolution of multidomain architectures. With this in mind, we study glutaredoxin (GRX domains, because these domains of approximately one hundred amino acids are widespread in archaea, bacteria and eukaryotes and participate in fusion proteins. GRXs are responsible for the reduction of protein disulfides or glutathione-protein mixed disulfides and are involved in cellular redox regulation, although their specific roles and targets are often unclear. Results In this work we analyze the distribution and evolution of GRX proteins in archaea, bacteria and eukaryotes. We study over one thousand GRX proteins, each containing at least one GRX domain, from hundreds of different organisms and trace the origin and evolution of the GRX domain within the tree of life. Conclusion Our results suggest that single domain GRX proteins of the CGFS and CPYC classes have, each, evolved through duplication and divergence from one initial gene that was present in the last common ancestor of all organisms. Remarkably, we identify a case of convergent evolution in domain architecture that involves the GRX domain. Two independent recombination events of a TRX domain to a GRX domain are likely to have occurred, which is an exception to the dominant mechanism of domain architecture evolution.

Cooperation evolution in random multiplicative environments

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Yaari, G.; Solomon, S.

2010-02-01

Most real life systems have a random component: the multitude of endogenous and exogenous factors influencing them result in stochastic fluctuations of the parameters determining their dynamics. These empirical systems are in many cases subject to noise of multiplicative nature. The special properties of multiplicative noise as opposed to additive noise have been noticed for a long while. Even though apparently and formally the difference between free additive vs. multiplicative random walks consists in just a move from normal to log-normal distributions, in practice the implications are much more far reaching. While in an additive context the emergence and survival of cooperation requires special conditions (especially some level of reward, punishment, reciprocity), we find that in the multiplicative random context the emergence of cooperation is much more natural and effective. We study the various implications of this observation and its applications in various contexts.

Characterization of the cavitating flow in converging-diverging nozzle based on experimental investigations

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Rudolf Pavel

2014-03-01

Full Text Available Cavitation phenomena occuring in converging-diverging nozzle (Venturi tube are described in the paper. A closed test circuit with possibility to control both flow rate and static pressure level were used. Loss coefficient was evaluated for different sigma numbers resulting in full „static“ characterization of the nozzle. Visualizations of the cavitation pattern development were acquired and matched with evolution of the loss coefficient. Three cavitation regimes are described: partial cavitation, fully developed cavitation, supercavitation.

Substitutions in the Glycogenin-1 Gene Are Associated with the Evolution of Endothermy in Sharks and Tunas.

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Ciezarek, Adam G; Dunning, Luke T; Jones, Catherine S; Noble, Leslie R; Humble, Emily; Stefanni, Sergio S; Savolainen, Vincent

2016-10-05

Despite 400-450 million years of independent evolution, a strong phenotypic convergence has occurred between two groups of fish: tunas and lamnid sharks. This convergence is characterized by centralization of red muscle, a distinctive swimming style (stiffened body powered through tail movements) and elevated body temperature (endothermy). Furthermore, both groups demonstrate elevated white muscle metabolic capacities. All these traits are unusual in fish and more likely evolved to support their fast-swimming, pelagic, predatory behavior. Here, we tested the hypothesis that their convergent evolution was driven by selection on a set of metabolic genes. We sequenced white muscle transcriptomes of six tuna, one mackerel, and three shark species, and supplemented this data set with previously published RNA-seq data. Using 26 species in total (including 7,032 tuna genes plus 1,719 shark genes), we constructed phylogenetic trees and carried out maximum-likelihood analyses of gene selection. We inferred several genes relating to metabolism to be under selection. We also found that the same one gene, glycogenin-1, evolved under positive selection independently in tunas and lamnid sharks, providing evidence of convergent selective pressures at gene level possibly underlying shared physiology. © The Author(s) 2016. Published by Oxford University Press on behalf of the Society for Molecular Biology and Evolution.

Heterogeneous convergence of regional house prices and the complexity in China

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Rui Lin

2015-12-01

Full Text Available The purpose of this research is to analyze the convergence of regional house prices and its complexity in China. In this purpose it used nonlinear time varying factor model. The obtained results have provided evidences for the existence of some degree of segmentation in China’s housing market. By further dynamic analysis of the convergence, we have found that important housing policies from Chinese central government can significantly alter the housing market but with a time lag of 4 to 5 months, and that quite different behaviors exist between the new house market and the second-hand house market in China, which provides the evidence for the complexity of housing market in China. Multiple factors together are the driving forces for the regional house price convergence. And the driving forces differ among three clubs. The basic conclusion provided from the realized research is that the conventional definitions of economic regions may not be appropriate to analyze house price segregation in China. Heterogeneous convergence exists in China’s regional house prices, indicating the complexity of regional house prices in China. And housing policies should be implemented with different focus among the regions. The way of the central government is to make housing policies aiming at different sub-markets of the new house market and the second-hand house market.

Flocking Control of Multiple Mobile Agents with the Rules of Avoiding Collision

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Hongtao Zhou

2015-01-01

Full Text Available This paper investigates the flocking and the coordinative control problems of multiple mobile agents with the rules of avoiding collision. We propose a set of control laws using hysteresis in adding new links and applying new potential function to guarantee that the fragmentation of the network can be avoided, under which all agents approach a common velocity vector, and asymptotically converge to a fixed value of interagent distances and collisions between agents can be avoided throughout the motion. Furthermore, we extend the flocking algorithm to solve the flocking situation of the group with a virtual leader agent. The laws can make all agents asymptotically approach the virtual leader and collisions can be avoided between agents in the motion evolution. Finally, some numerical simulations are showed to illustrate the theoretical results.

Vadose zone flow convergence test suite

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Butcher, B. T. [Savannah River Site (SRS), Aiken, SC (United States). Savannah River National Lab. (SRNL)

2017-06-05

Performance Assessment (PA) simulations for engineered disposal systems at the Savannah River Site involve highly contrasting materials and moisture conditions at and near saturation. These conditions cause severe convergence difficulties that typically result in unacceptable convergence or long simulation times or excessive analyst effort. Adequate convergence is usually achieved in a trial-anderror manner by applying under-relaxation to the Saturation or Pressure variable, in a series of everdecreasing RELAxation values. SRNL would like a more efficient scheme implemented inside PORFLOW to achieve flow convergence in a more reliable and efficient manner. To this end, a suite of test problems that illustrate these convergence problems is provided to facilitate diagnosis and development of an improved convergence strategy. The attached files are being transmitted to you describing the test problem and proposed resolution.

Collaborative Learning Using a Project across Multiple Business Courses: A Cognitive Load and Knowledge Convergence Approach

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Bhowmick, Sandeep; Chandra, Aruna; Harper, Jeffrey S.; Sweetin, Vernon

2015-01-01

Four business professors at a state university in the Midwestern United States launched a collaborative learning project grounded in cognitive learning theory and knowledge convergence theory with the objective of assessing student learning gains in cross-functional knowledge (CFK), course-related knowledge (CRK), and overall satisfaction with…

The Pathwise Numerical Approximation of Stationary Solutions of Semilinear Stochastic Evolution Equations

International Nuclear Information System (INIS)

Caraballo, T.; Kloeden, P.E.

2006-01-01

Under a one-sided dissipative Lipschitz condition on its drift, a stochastic evolution equation with additive noise of the reaction-diffusion type is shown to have a unique stochastic stationary solution which pathwise attracts all other solutions. A similar situation holds for each Galerkin approximation and each implicit Euler scheme applied to these Galerkin approximations. Moreover, the stationary solution of the Euler scheme converges pathwise to that of the Galerkin system as the stepsize tends to zero and the stationary solutions of the Galerkin systems converge pathwise to that of the evolution equation as the dimension increases. The analysis is carried out on random partial and ordinary differential equations obtained from their stochastic counterparts by subtraction of appropriate Ornstein-Uhlenbeck stationary solutions

Thoughts on Multi-sphere Study in the Indo-Pacific Convergent Zone

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Wang, F.

2016-12-01

Interactions of the ocean with other components of the earth system, such as atmosphere, lithosphere, and biosphere are the front and hotspot of the ocean and earth sciences. In the Indonesian Archipelago and adjacent western Pacific and eastern Indian Oceans, both the upper oceanic circulation and lower atmospheric circulation convergent and consequently enhance the fresh water and heat fluxes, affecting the East Asian and global climate. This region is considered as the world's center of marine bio-diversity and sediment discharge, as well as the collision center of the Eurasian, Indian and Pacific plates. Why and how the energy and material of multiple spheres convergent toward the region are important scientific issues on the front of earth system science and marine sciences, and need to be investigated through international cooperation.

A Two-Dimensional Helmholtz Equation Solution for the Multiple Cavity Scattering Problem

Science.gov (United States)

2013-02-01

obtained by using the block Gauss – Seidel iterative meth- od. To show the convergence of the iterative method, we define the error between two...models to the general multiple cavity setting. Numerical examples indicate that the convergence of the Gauss – Seidel iterative method depends on the...variational approach. A block Gauss – Seidel iterative method is introduced to solve the cou- pled system of the multiple cavity scattering problem, where

Weak entropy inequalities and entropic convergence

Institute of Scientific and Technical Information of China (English)

2008-01-01

A criterion for algebraic convergence of the entropy is presented and an algebraic convergence result for the entropy of an exclusion process is improved. A weak entropy inequality is considered and its relationship to entropic convergence is discussed.

Convergence of mayer expansions

International Nuclear Information System (INIS)

Brydges, D.C.

1986-01-01

The tree graph bound of Battle and Federbush is extended and used to provide a simple criterion for the convergence of (iterated) Mayer expansions. As an application estimates on the radius of convergence of the Mayer expansion for the two-dimensional Yukawa gas (nonstable interaction) are obtained

Repeated functional convergent effects of NaV1.7 on acid insensitivity in hibernating mammals.

Science.gov (United States)

Liu, Zhen; Wang, Wei; Zhang, Tong-Zuo; Li, Gong-Hua; He, Kai; Huang, Jing-Fei; Jiang, Xue-Long; Murphy, Robert W; Shi, Peng

2014-02-07

Hibernating mammals need to be insensitive to acid in order to cope with conditions of high CO2; however, the molecular basis of acid tolerance remains largely unknown. The African naked mole-rat (Heterocephalus glaber) and hibernating mammals share similar environments and physiological features. In the naked mole-rat, acid insensitivity has been shown to be conferred by the functional motif of the sodium ion channel NaV1.7. There is now an opportunity to evaluate acid insensitivity in other taxa. In this study, we tested for functional convergence of NaV1.7 in 71 species of mammals, including 22 species that hibernate. Our analyses revealed a functional convergence of amino acid sequences, which occurred at least six times independently in mammals that hibernate. Evolutionary analyses determined that the convergence results from both parallel and divergent evolution of residues in the functional motif. Our findings not only identify the functional molecules responsible for acid insensitivity in hibernating mammals, but also open new avenues to elucidate the molecular underpinnings of acid insensitivity in mammals.

Convergence of cranial visceral afferents within the solitary tract nucleus.

Science.gov (United States)

McDougall, Stuart J; Peters, James H; Andresen, Michael C

2009-10-14

Primary afferent axons within the solitary tract (ST) relay homeostatic information via glutamatergic synapses directly to second-order neurons within the nucleus of the solitary tract (NTS). These primary afferents arise from multiple organ systems and relay multiple sensory modalities. How this compact network organizes the flow of primary afferent information will shape central homeostatic control. To assess afferent convergence and divergence, we recorded ST-evoked synaptic responses in pairs of medial NTS neurons in horizontal brainstem slices. ST shocks activated EPSCs along monosynaptic or polysynaptic pathways. Gradations in shock intensity discriminated multiple inputs and stimulus recruitment profiles indicated that each EPSC was unitary. In 24 pairs, 75% were second-order neurons with 64% receiving one direct ST input with the remainder receiving additional convergent ST afferent inputs (22% two; 14% three monosynaptic ST-EPSCs). Some (34%) second-order neurons received polysynaptic EPSCs. Neurons receiving only higher-order inputs were uncommon (13%). Most ST-EPSCs were completely independent, but 4 EPSCs of a total of 81 had equal thresholds, highly correlated latencies, and synchronized synaptic failures consistent with divergence from a single source ST axon or from a common interneuron producing a pair of polysynaptic EPSCs. We conclude that ST afferent inputs are remarkably independent with little evidence of substantial shared information. Individual cells receive highly focused information from the viscera. Thus, afferent excitation of second-order NTS neurons is generally dominated by single visceral afferents and therefore focused on a single afferent modality and/or organ region.

Evolution of the Pannonian basin and its geothermal resources

NARCIS (Netherlands)

Horváth, F.; Musitz, B.; Balázs, A.; Végh, A.; Uhrin, A.; Nádor, A.; Koroknai, B.; Pap, N.; Tóth, T.; Wórum, G.

The Pannonian basin is an integral part of the convergence zone between the Eurasian and Nubian plates characterized by active subductions of oceanic and continental plates, and formation of backarc basins. The first part of this paper presents an overview of the evolution of the

The evolution of primate general and cultural intelligence.

Science.gov (United States)

Reader, Simon M; Hager, Yfke; Laland, Kevin N

2011-04-12

There are consistent individual differences in human intelligence, attributable to a single 'general intelligence' factor, g. The evolutionary basis of g and its links to social learning and culture remain controversial. Conflicting hypotheses regard primate cognition as divided into specialized, independently evolving modules versus a single general process. To assess how processes underlying culture relate to one another and other cognitive capacities, we compiled ecologically relevant cognitive measures from multiple domains, namely reported incidences of behavioural innovation, social learning, tool use, extractive foraging and tactical deception, in 62 primate species. All exhibited strong positive associations in principal component and factor analyses, after statistically controlling for multiple potential confounds. This highly correlated composite of cognitive traits suggests social, technical and ecological abilities have coevolved in primates, indicative of an across-species general intelligence that includes elements of cultural intelligence. Our composite species-level measure of general intelligence, 'primate g(S)', covaried with both brain volume and captive learning performance measures. Our findings question the independence of cognitive traits and do not support 'massive modularity' in primate cognition, nor an exclusively social model of primate intelligence. High general intelligence has independently evolved at least four times, with convergent evolution in capuchins, baboons, macaques and great apes.

On new classes of solutions of nonlinear partial differential equations in the form of convergent special series

Science.gov (United States)

Filimonov, M. Yu.

2017-12-01

The method of special series with recursively calculated coefficients is used to solve nonlinear partial differential equations. The recurrence of finding the coefficients of the series is achieved due to a special choice of functions, in powers of which the solution is expanded in a series. We obtain a sequence of linear partial differential equations to find the coefficients of the series constructed. In many cases, one can deal with a sequence of linear ordinary differential equations. We construct classes of solutions in the form of convergent series for a certain class of nonlinear evolution equations. A new class of solutions of generalized Boussinesque equation with an arbitrary function in the form of a convergent series is constructed.

Multiple Stars Across the H-R Diagram

CERN Document Server

Hubrig, Swetlana; Tokovinin, Andrei; Proceedings of the ESO Workshop held in Garching, Germany, 12-15 July 2005

2008-01-01

Stars show a marked tendency to be in systems of different multiplicity, ranging from simple binaries and triples to globular clusters with several 10,000's of stars. The formation and evolution of multiple systems remains a challenging part of astrophysics, and the contributions in this book report on the significant progress that had been made in this research field in the last years. The reader will find a variety of research topics addressed, such as the dynamical evolution in multiple stars, the effects of the environment on multiple system parameters, stellar evolution within multiple stars, multiplicity of massive stars, pre-main sequence and intermediate mass stars, multiplicity of low-mass stars from embedded protostars to open clusters, and brown dwarfs and extrasolar planets in multiples. This book presents the proceedings of the ESO Workshop on Multiple Stars across the H-R Diagram held in the summer of 2005.

Discrete conservation laws and the convergence of long time simulations of the mkdv equation

Science.gov (United States)

Gorria, C.; Alejo, M. A.; Vega, L.

2013-02-01

Pseudospectral collocation methods and finite difference methods have been used for approximating an important family of soliton like solutions of the mKdV equation. These solutions present a structural instability which make difficult to approximate their evolution in long time intervals with enough accuracy. The standard numerical methods do not guarantee the convergence to the proper solution of the initial value problem and often fail by approaching solutions associated to different initial conditions. In this frame the numerical schemes that preserve the discrete invariants related to some conservation laws of this equation produce better results than the methods which only take care of a high consistency order. Pseudospectral spatial discretization appear as the most robust of the numerical methods, but finite difference schemes are useful in order to analyze the rule played by the conservation of the invariants in the convergence.

Analogue Modeling of Oblique Convergent Strike-Slip Faulting and Application to The Seram Island, Eastern Indonesia

Directory of Open Access Journals (Sweden)

Benyamin Sapiie

2014-12-01

Full Text Available DOI:10.17014/ijog.v1i3.189Sandbox experiment is one of the types of analogue modeling in geological sciences in which the main purpose is simulating deformation style and structural evolution of the sedimentary basin.  Sandbox modeling is one of the effective ways in conducting physically modeling and evaluates complex deformation of sedimentary rocks. The main purpose of this paper is to evaluate structural geometry and deformation history of oblique convergent deformation using of integrated technique of analogue sandbox modeling applying to deformation of Seram Fold-Thrust-Belt (SFTB in the Seram Island, Eastern Indonesia. Oblique convergent strike-slip deformation has notoriously generated area with structural complex geometry and pattern resulted from role of various local parameters that control stress distributions. Therefore, a special technique is needed for understanding and solving such problem in particular to relate 3D fault geometry and its evolution. The result of four case (Case 1 to 4 modeling setting indicated that two of modeling variables clearly affected in our sandbox modeling results; these are lithological variation (mainly stratigraphy of Seram Island and pre-existing basement fault geometry (basement configuration. Lithological variation was mainly affected in the total number of faults development.  On the other hand, pre-existing basement fault geometry was highly influenced in the end results particularly fault style and pattern as demonstrated in Case 4 modeling.  In addition, this study concluded that deformation in the Seram Island is clearly best described using oblique convergent strike-slip (transpression stress system.

Evolution of f{sub NL} to the adiabatic limit

Energy Technology Data Exchange (ETDEWEB)

Elliston, Joseph; Mulryne, David J.; Tavakol, Reza [School of Physics and Astronomy, Queen Mary University of London, Mile End Road, London E1 4NS (United Kingdom); Seery, David, E-mail: J.Elliston@qmul.ac.uk, E-mail: D.Mulryne@qmul.ac.uk, E-mail: D.Seery@sussex.ac.uk, E-mail: R.Tavakol@qmul.ac.uk [Astronomy Centre, University of Sussex, Falmer, Brighton BN1 9QH (United Kingdom)

2011-11-01

We study inflationary perturbations in multiple-field models, for which ζ typically evolves until all isocurvature modes decay — the {sup a}diabatic limit{sup .} We use numerical methods to explore the sensitivity of the local-shape bispectrum to the process by which this limit is achieved, finding an appreciable dependence on model-specific data such as the time at which slow-roll breaks down or the timescale of reheating. In models with a sum-separable potential where the isocurvature modes decay before the end of the slow-roll phase we give an analytic criterion for the asymptotic value of f{sub NL} to be large. Other examples can be constructed using a waterfall field to terminate inflation while f{sub NL} is transiently large, caused by descent from a ridge or convergence into a valley. We show that these two types of evolution are distinguished by the sign of the bispectrum, and give approximate expressions for the peak f{sub NL}.

An efficient method for generalized linear multiplicative programming problem with multiplicative constraints.

Science.gov (United States)

Zhao, Yingfeng; Liu, Sanyang

2016-01-01

We present a practical branch and bound algorithm for globally solving generalized linear multiplicative programming problem with multiplicative constraints. To solve the problem, a relaxation programming problem which is equivalent to a linear programming is proposed by utilizing a new two-phase relaxation technique. In the algorithm, lower and upper bounds are simultaneously obtained by solving some linear relaxation programming problems. Global convergence has been proved and results of some sample examples and a small random experiment show that the proposed algorithm is feasible and efficient.

Specialized motor-driven dusp1 expression in the song systems of multiple lineages of vocal learning birds.

Directory of Open Access Journals (Sweden)

Haruhito Horita

Full Text Available Mechanisms for the evolution of convergent behavioral traits are largely unknown. Vocal learning is one such trait that evolved multiple times and is necessary in humans for the acquisition of spoken language. Among birds, vocal learning is evolved in songbirds, parrots, and hummingbirds. Each time similar forebrain song nuclei specialized for vocal learning and production have evolved. This finding led to the hypothesis that the behavioral and neuroanatomical convergences for vocal learning could be associated with molecular convergence. We previously found that the neural activity-induced gene dual specificity phosphatase 1 (dusp1 was up-regulated in non-vocal circuits, specifically in sensory-input neurons of the thalamus and telencephalon; however, dusp1 was not up-regulated in higher order sensory neurons or motor circuits. Here we show that song motor nuclei are an exception to this pattern. The song nuclei of species from all known vocal learning avian lineages showed motor-driven up-regulation of dusp1 expression induced by singing. There was no detectable motor-driven dusp1 expression throughout the rest of the forebrain after non-vocal motor performance. This pattern contrasts with expression of the commonly studied activity-induced gene egr1, which shows motor-driven expression in song nuclei induced by singing, but also motor-driven expression in adjacent brain regions after non-vocal motor behaviors. In the vocal non-learning avian species, we found no detectable vocalizing-driven dusp1 expression in the forebrain. These findings suggest that independent evolutions of neural systems for vocal learning were accompanied by selection for specialized motor-driven expression of the dusp1 gene in those circuits. This specialized expression of dusp1 could potentially lead to differential regulation of dusp1-modulated molecular cascades in vocal learning circuits.

Beyond Brainstorming: Exploring Convergence in Teams

Science.gov (United States)

Seeber, Isabella; de Vreede, Gert-Jan; Maier, Ronald; Weber, Barbara

2017-01-01

Abstract Collaborative brainstorming is often followed by a convergence activity where teams extract the most promising ideas on a useful level of detail from the brainstorming results. Contrary to the wealth of research on electronic brainstorming, there is a dearth of research on convergence. We used experimental methods for an in-depth exploration of two facilitation-based interventions in a convergence activity: attention guidance (focusing participants on procedures to execute a convergence task) and discussion encouragement (engaging participants in conversations to combine knowledge on ideas). Our findings show that both attention guidance and discussion encouragement are correlated with higher convergence quality. We argue that attention guidance’s contribution is in its support of coordination, information processing, and goal specification. Similar, we argue that discussion encouragement’s contribution is in its stimulation of idea clarification and idea combination. Contrary to past research, our findings further show that satisfaction was higher after convergence than after brainstorming. PMID:29399005

Convergent Polishing: A Simple, Rapid, Full Aperture Polishing Process of High Quality Optical Flats & Spheres

Science.gov (United States)

Suratwala, Tayyab; Steele, Rusty; Feit, Michael; Dylla-Spears, Rebecca; Desjardin, Richard; Mason, Dan; Wong, Lana; Geraghty, Paul; Miller, Phil; Shen, Nan

2014-01-01

Convergent Polishing is a novel polishing system and method for finishing flat and spherical glass optics in which a workpiece, independent of its initial shape (i.e., surface figure), will converge to final surface figure with excellent surface quality under a fixed, unchanging set of polishing parameters in a single polishing iteration. In contrast, conventional full aperture polishing methods require multiple, often long, iterative cycles involving polishing, metrology and process changes to achieve the desired surface figure. The Convergent Polishing process is based on the concept of workpiece-lap height mismatch resulting in pressure differential that decreases with removal and results in the workpiece converging to the shape of the lap. The successful implementation of the Convergent Polishing process is a result of the combination of a number of technologies to remove all sources of non-uniform spatial material removal (except for workpiece-lap mismatch) for surface figure convergence and to reduce the number of rogue particles in the system for low scratch densities and low roughness. The Convergent Polishing process has been demonstrated for the fabrication of both flats and spheres of various shapes, sizes, and aspect ratios on various glass materials. The practical impact is that high quality optical components can be fabricated more rapidly, more repeatedly, with less metrology, and with less labor, resulting in lower unit costs. In this study, the Convergent Polishing protocol is specifically described for fabricating 26.5 cm square fused silica flats from a fine ground surface to a polished ~λ/2 surface figure after polishing 4 hr per surface on a 81 cm diameter polisher. PMID:25489745

Genome diversity and divergence in Drosophila mauritiana: multiple signatures of faster X evolution.

Science.gov (United States)

Garrigan, Daniel; Kingan, Sarah B; Geneva, Anthony J; Vedanayagam, Jeffrey P; Presgraves, Daven C

2014-09-04

Drosophila mauritiana is an Indian Ocean island endemic species that diverged from its two sister species, Drosophila simulans and Drosophila sechellia, approximately 240,000 years ago. Multiple forms of incomplete reproductive isolation have evolved among these species, including sexual, gametic, ecological, and intrinsic postzygotic barriers, with crosses among all three species conforming to Haldane's rule: F(1) hybrid males are sterile and F(1) hybrid females are fertile. Extensive genetic resources and the fertility of hybrid females have made D. mauritiana, in particular, an important model for speciation genetics. Analyses between D. mauritiana and both of its siblings have shown that the X chromosome makes a disproportionate contribution to hybrid male sterility. But why the X plays a special role in the evolution of hybrid sterility in these, and other, species remains an unsolved problem. To complement functional genetic analyses, we have investigated the population genomics of D. mauritiana, giving special attention to differences between the X and the autosomes. We present a de novo genome assembly of D. mauritiana annotated with RNAseq data and a whole-genome analysis of polymorphism and divergence from ten individuals. Our analyses show that, relative to the autosomes, the X chromosome has reduced nucleotide diversity but elevated nucleotide divergence; an excess of recurrent adaptive evolution at its protein-coding genes; an excess of recent, strong selective sweeps; and a large excess of satellite DNA. Interestingly, one of two centimorgan-scale selective sweeps on the D. mauritiana X chromosome spans a region containing two sex-ratio meiotic drive elements and a high concentration of satellite DNA. Furthermore, genes with roles in reproduction and chromosome biology are enriched among genes that have histories of recurrent adaptive protein evolution. Together, these genome-wide analyses suggest that genetic conflict and frequent positive natural

Semantic Convergence in the Bilingual Lexicon

Science.gov (United States)

Ameel, Eef; Malt, Barbara C.; Storms, Gert; Van Assche, Fons

2009-01-01

Bilinguals' lexical mappings for their two languages have been found to converge toward a common naming pattern. The present paper investigates in more detail how semantic convergence is manifested in bilingual lexical knowledge. We examined how semantic convergence affects the centers and boundaries of lexical categories for common household…

Convergence semigroup actions: generalized quotients

Directory of Open Access Journals (Sweden)

H. Boustique

2009-10-01

Full Text Available Continuous actions of a convergence semigroup are investigated in the category of convergence spaces. Invariance properties of actions as well as properties of a generalized quotient space are presented

Globalization and Contemporary Fertility Convergence.

Science.gov (United States)

Hendi, Arun S

2017-09-01

The rise of the global network of nation-states has precipitated social transformations throughout the world. This article examines the role of political and economic globalization in driving fertility convergence across countries between 1965 and 2009. While past research has typically conceptualized fertility change as a country-level process, this study instead employs a theoretical and methodological framework that examines differences in fertility between pairs of countries over time. Convergence in fertility between pairs of countries is hypothesized to result from increased cross-country connectedness and cross-national transmission of fertility-related schemas. I investigate the impact of various cross-country ties, including ties through bilateral trade, intergovernmental organizations, and regional trade blocs, on fertility convergence. I find that globalization acts as a form of social interaction to produce fertility convergence. There is significant heterogeneity in the effects of different cross-country ties. In particular, trade with rich model countries, joint participation in the UN and UNESCO, and joining a free trade agreement all contribute to fertility convergence between countries. Whereas the prevailing focus in fertility research has been on factors producing fertility declines, this analysis highlights specific mechanisms-trade and connectedness through organizations-leading to greater similarity in fertility across countries. Globalization is a process that propels the spread of culturally laden goods and schemas impinging on fertility, which in turn produces fertility convergence.

Evolution of the PWWP-domain encoding genes in the plant and animal lineages

Directory of Open Access Journals (Sweden)

Alvarez-Venegas Raúl

2012-06-01

Full Text Available Abstract Background Conserved domains are recognized as the building blocks of eukaryotic proteins. Domains showing a tendency to occur in diverse combinations (‘promiscuous’ domains are involved in versatile architectures in proteins with different functions. Current models, based on global-level analyses of domain combinations in multiple genomes, have suggested that the propensity of some domains to associate with other domains in high-level architectures increases with organismal complexity. Alternative models using domain-based phylogenetic trees propose that domains have become promiscuous independently in different lineages through convergent evolution and are, thus, random with no functional or structural preferences. Here we test whether complex protein architectures have occurred by accretion from simpler systems and whether the appearance of multidomain combinations parallels organismal complexity. As a model, we analyze the modular evolution of the PWWP domain and ask whether its appearance in combinations with other domains into multidomain architectures is linked with the occurrence of more complex life-forms. Whether high-level combinations of domains are conserved and transmitted as stable units (cassettes through evolution is examined in the genomes of plant or metazoan species selected for their established position in the evolution of the respective lineages. Results Using the domain-tree approach, we analyze the evolutionary origins and distribution patterns of the promiscuous PWWP domain to understand the principles of its modular evolution and its existence in combination with other domains in higher-level protein architectures. We found that as a single module the PWWP domain occurs only in proteins with a limited, mainly, species-specific distribution. Earlier, it was suggested that domain promiscuity is a fast-changing (volatile feature shaped by natural selection and that only a few domains retain their promiscuity

Zipf rank approach and cross-country convergence of incomes

Science.gov (United States)

Shao, Jia; Ivanov, Plamen Ch.; Urošević, Branko; Stanley, H. Eugene; Podobnik, Boris

2011-05-01

We employ a concept popular in physics —the Zipf rank approach— in order to estimate the number of years that EU members would need in order to achieve "convergence" of their per capita incomes. Assuming that trends in the past twenty years continue to hold in the future, we find that after t≈30 years both developing and developed EU countries indexed by i will have comparable values of their per capita gross domestic product {\\cal G}_{i,t} . Besides the traditional Zipf rank approach we also propose a weighted Zipf rank method. In contrast to the EU block, on the world level the Zipf rank approach shows that, between 1960 and 2009, cross-country income differences increased over time. For a brief period during the 2007-2008 global economic crisis, at world level the {\\cal G}_{i,t} of richer countries declined more rapidly than the {\\cal G}_{i,t} of poorer countries, in contrast to EU where the {\\cal G}_{i,t} of developing EU countries declined faster than the {\\cal G}_{i,t} of developed EU countries, indicating that the recession interrupted the convergence between EU members. We propose a simple model of GDP evolution that accounts for the scaling we observe in the data.

An axisymmetric evolution code for the Einstein equations on hyperboloidal slices

International Nuclear Information System (INIS)

Rinne, Oliver

2010-01-01

We present the first stable dynamical numerical evolutions of the Einstein equations in terms of a conformally rescaled metric on hyperboloidal hypersurfaces extending to future null infinity. Axisymmetry is imposed in order to reduce the computational cost. The formulation is based on an earlier axisymmetric evolution scheme, adapted to time slices of constant mean curvature. Ideas from a previous study by Moncrief and the author are applied in order to regularize the formally singular evolution equations at future null infinity. Long-term stable and convergent evolutions of Schwarzschild spacetime are obtained, including a gravitational perturbation. The Bondi news function is evaluated at future null infinity.

Dynamic evolution of Geranium mitochondrial genomes through multiple horizontal and intracellular gene transfers.

Science.gov (United States)

Park, Seongjun; Grewe, Felix; Zhu, Andan; Ruhlman, Tracey A; Sabir, Jamal; Mower, Jeffrey P; Jansen, Robert K

2015-10-01

The exchange of genetic material between cellular organelles through intracellular gene transfer (IGT) or between species by horizontal gene transfer (HGT) has played an important role in plant mitochondrial genome evolution. The mitochondrial genomes of Geraniaceae display a number of unusual phenomena including highly accelerated rates of synonymous substitutions, extensive gene loss and reduction in RNA editing. Mitochondrial DNA sequences assembled for 17 species of Geranium revealed substantial reduction in gene and intron content relative to the ancestor of the Geranium lineage. Comparative analyses of nuclear transcriptome data suggest that a number of these sequences have been functionally relocated to the nucleus via IGT. Evidence for rampant HGT was detected in several Geranium species containing foreign organellar DNA from diverse eudicots, including many transfers from parasitic plants. One lineage has experienced multiple, independent HGT episodes, many of which occurred within the past 5.5 Myr. Both duplicative and recapture HGT were documented in Geranium lineages. The mitochondrial genome of Geranium brycei contains at least four independent HGT tracts that are absent in its nearest relative. Furthermore, G. brycei mitochondria carry two copies of the cox1 gene that differ in intron content, providing insight into contrasting hypotheses on cox1 intron evolution. © 2015 The Authors. New Phytologist © 2015 New Phytologist Trust.

Convergence of Networks

DEFF Research Database (Denmark)

Prasad, Ramjee; Ruggieri, Marina

2008-01-01

The paper focuses on the revolutionary changes that could characterise the future of networks. Those changes involve many aspects in the conceivement and exploitation of networks: architecture, services, technologies and modeling. The convergence of wired and wireless technologies along...... with the integration of system componennts and the convergence of services (e.g. communications and navigation) are only some of the elements that shape the perpsected mosaic. Authors delineate this vision, highlighting the presence of the space and stratospheric components and the related services as building block...

OpenMC In Situ Source Convergence Detection

Energy Technology Data Exchange (ETDEWEB)

Aldrich, Garrett Allen [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Univ. of California, Davis, CA (United States); Dutta, Soumya [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); The Ohio State Univ., Columbus, OH (United States); Woodring, Jonathan Lee [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

2016-05-07

We designed and implemented an in situ version of particle source convergence for the OpenMC particle transport simulator. OpenMC is a Monte Carlo based-particle simulator for neutron criticality calculations. For the transport simulation to be accurate, source particles must converge on a spatial distribution. Typically, convergence is obtained by iterating the simulation by a user-settable, fixed number of steps, and it is assumed that convergence is achieved. We instead implement a method to detect convergence, using the stochastic oscillator for identifying convergence of source particles based on their accumulated Shannon Entropy. Using our in situ convergence detection, we are able to detect and begin tallying results for the full simulation once the proper source distribution has been confirmed. Our method ensures that the simulation is not started too early, by a user setting too optimistic parameters, or too late, by setting too conservative a parameter.

Fully-converged three-dimensional collision-induced dissociation calculations with Faddeev-AGS theory

International Nuclear Information System (INIS)

Haftel, M.I.; Lim, T.K.

1981-09-01

The first fully-converged quantum-mechanical calculation of the collision-induced dissociation cross section in a three-dimensional-model system of three helium-like atoms is reported. Faddeev-AGS theory is used. It yields as a bonus the elastic atom-diatom cross section. The obtained results resemble those from some collinear models but indicate clearly the futility of multiple-scattering approximations except at hyperthermal energies. (orig.)

The Convergence in Spatial Tasks

Directory of Open Access Journals (Sweden)

Vladimir P. Kulagin

2013-01-01

Full Text Available The article reveals the problem of convergence of direct and inverse problems in Earth Sciences, describes the features and application of these problems, discloses analytical features of direct and inverse problems. The convergence criteria and conditions for convergence were presented. This work is supported by the Grant of the Government of the Russian Federation for support of scientific research, implemented under the supervision of leading scientists in Russian institutions of higher education in the field "Space Research and Technologies" in 2011–2013.

Nonlinear Multiplicative Schwarz Preconditioning in Natural Convection Cavity Flow

KAUST Repository

Liu, Lulu

2017-03-17

A natural convection cavity flow problem is solved using nonlinear multiplicative Schwarz preconditioners, as a Gauss-Seidel-like variant of additive Schwarz preconditioned inexact Newton (ASPIN). The nonlinear preconditioning extends the domain of convergence of Newton’s method to high Rayleigh numbers. Convergence performance varies widely with respect to different groupings of the fields of this multicomponent problem, and with respect to different orderings of the groupings.

Nonlinear Multiplicative Schwarz Preconditioning in Natural Convection Cavity Flow

KAUST Repository

Liu, Lulu; Zhang, Wei; Keyes, David E.

2017-01-01

A natural convection cavity flow problem is solved using nonlinear multiplicative Schwarz preconditioners, as a Gauss-Seidel-like variant of additive Schwarz preconditioned inexact Newton (ASPIN). The nonlinear preconditioning extends the domain of convergence of Newton’s method to high Rayleigh numbers. Convergence performance varies widely with respect to different groupings of the fields of this multicomponent problem, and with respect to different orderings of the groupings.

A mathematical analysis of multiple-target SELEX.

Science.gov (United States)

Seo, Yeon-Jung; Chen, Shiliang; Nilsen-Hamilton, Marit; Levine, Howard A

2010-10-01

SELEX (Systematic Evolution of Ligands by Exponential Enrichment) is a procedure by which a mixture of nucleic acids can be fractionated with the goal of identifying those with specific biochemical activities. One combines the mixture with a specific target molecule and then separates the target-NA complex from the resulting reactions. The target-NA complex is separated from the unbound NA by mechanical means (such as by filtration), the NA is eluted from the complex, amplified by PCR (polymerase chain reaction), and the process repeated. After several rounds, one should be left with the nucleic acids that best bind to the target. The problem was first formulated mathematically in Irvine et al. (J. Mol. Biol. 222:739-761, 1991). In Levine and Nilsen-Hamilton (Comput. Biol. Chem. 31:11-25, 2007), a mathematical analysis of the process was given. In Vant-Hull et al. (J. Mol. Biol. 278:579-597, 1998), multiple target SELEX was considered. It was assumed that each target has a single nucleic acid binding site that permits occupation by no more than one nucleic acid. Here, we revisit Vant-Hull et al. (J. Mol. Biol. 278:579-597, 1998) using the same assumptions. The iteration scheme is shown to be convergent and a simplified algorithm is given. Our interest here is in the behavior of the multiple target SELEX process as a discrete "time" dynamical system. Our goal is to characterize the limiting states and their dependence on the initial distribution of nucleic acid and target fraction components. (In multiple target SELEX, we vary the target component fractions, but not their concentrations, as fixed and the initial pool of nucleic acids as a variable starting condition). Given N nucleic acids and a target consisting of M subtarget component species, there is an M × N matrix of affinities, the (i,j) entry corresponding to the affinity of the jth nucleic acid for the ith subtarget. We give a structure condition on this matrix that is equivalent to the following

Evolution of morphology, ontogeny and life cycles within the Crustacea Thecostraca

DEFF Research Database (Denmark)

Høeg, Jens Thorvald; Perez-Losada, M; Glenner, H

2009-01-01

metamorphosis and endoparasitism known from the Rhizocephala and strongly indicated for the Facetotecta are the result of convergent evolution. We also discuss reproductive systems, which range from separate sexes, over hermaphrodites combined with a separate male sex (androdioecy), to pure hermaphroditism...

Computation of a long-time evolution in a Schroedinger system

International Nuclear Information System (INIS)

Girard, R.; Kroeger, H.; Labelle, P.; Bajzer, Z.

1988-01-01

We compare different techniques for the computation of a long-time evolution and the S matrix in a Schroedinger system. As an application we consider a two-nucleon system interacting via the Yamaguchi potential. We suggest computation of the time evolution for a very short time using Pade approximants, the long-time evolution being obtained by iterative squaring. Within the technique of strong approximation of Moller wave operators (SAM) we compare our calculation with computation of the time evolution in the eigenrepresentation of the Hamiltonian and with the standard Lippmann-Schwinger solution for the S matrix. We find numerical agreement between these alternative methods for time-evolution computation up to half the number of digits of internal machine precision, and fairly rapid convergence of both techniques towards the Lippmann-Schwinger solution

Does aquatic foraging impact head shape evolution in snakes?

Science.gov (United States)

Segall, Marion; Cornette, Raphaël; Fabre, Anne-Claire; Godoy-Diana, Ramiro; Herrel, Anthony

2016-08-31

Evolutionary trajectories are often biased by developmental and historical factors. However, environmental factors can also impose constraints on the evolutionary trajectories of organisms leading to convergence of morphology in similar ecological contexts. The physical properties of water impose strong constraints on aquatic feeding animals by generating pressure waves that can alert prey and potentially push them away from the mouth. These hydrodynamic constraints have resulted in the independent evolution of suction feeding in most groups of secondarily aquatic tetrapods. Despite the fact that snakes cannot use suction, they have invaded the aquatic milieu many times independently. Here, we test whether the aquatic environment has constrained head shape evolution in snakes and whether shape converges on that predicted by biomechanical models. To do so, we used three-dimensional geometric morphometrics and comparative, phylogenetically informed analyses on a large sample of aquatic snake species. Our results show that aquatic snakes partially conform to our predictions and have a narrower anterior part of the head and dorsally positioned eyes and nostrils. This morphology is observed, irrespective of the phylogenetic relationships among species, suggesting that the aquatic environment does indeed drive the evolution of head shape in snakes, thus biasing the evolutionary trajectory of this group of animals. © 2016 The Author(s).

Plant volatile eliciting FACs in lepidopteran caterpillars, fruit flies and crickets: a convergent evolution or phylogenetic inheritance?

Directory of Open Access Journals (Sweden)

Naoko eYoshinaga

2014-04-01

Full Text Available Fatty acid amino acid conjugates (FACs, first identified in lepidopteran caterpillar spit as elicitors of plant volatile emission, also have been reported as major components in gut tracts of Drosophila melanogaster and cricket Teleogryllus taiwanemma. The profile of FAC analogs in these two insects was similar to that of tobacco hornworm Manduca sexta, showing glutamic acid conjugates predominantly over glutamine conjugates. The physiological function of FACs is presumably to enhance nitrogen assimilation in Spodoptera litura larvae, but in other insects it is totally unknown. Whether these insects share a common synthetic mechanism of FACs is also unclear. In this study, the biosynthesis of FACs was examined in vitro in five lepidopteran species (M. sexta, Cephonodes hylas, silkworm, S. litura, and Mythimna separata, fruit fly larvae and T. taiwanemma. The fresh midgut tissues of all of the tested insects showed the ability to synthesize glutamine conjugates in vitro when incubated with glutamine and sodium linolenate. Such direct conjugation was also observed for glutamic acid conjugates in all the insects but the product amount was very small and did not reflect the in vivo FAC patterns in each species. In fruit fly larvae, the predominance of glutamic acid conjugates could be explained by a shortage of substrate glutamine in midgut tissues, and in M. sexta, a rapid hydrolysis of glutamine conjugates has been reported. In crickets, we found an additional unique biosynthetic pathway for glutamic acid conjugates. T. taiwanemma converted glutamine conjugates to glutamic acid conjugates by deaminating the side chain of the glutamine moiety. Considering these findings together with previous results, a possibility that FACs in these insects are results of convergent evolution can not be ruled out, but it is more likely that the ancestral insects had the glutamine conjugates and crickets and other insects developed glutamic acid conjugates in a

Continuity in Λ-variation of functions of several variables and convergence of multiple Fourier series

International Nuclear Information System (INIS)

Bakhvalov, A N

2002-01-01

The behaviour of rectangular partial sums of the Fourier series of functions of several variables having bounded Λ-variation is considered. It is proved that if a continuous function is also continuous in harmonic variation, then its Fourier series uniformly converges in the sense of Pringsheim. On the other hand, it is demonstrated that in dimensions greater than 2 there always exists a continuous function of bounded harmonic variation with Fourier series divergent over cubes at the origin

Convergent evolution of jaws between spinosaurid dinosaurs and pike conger eels

Directory of Open Access Journals (Sweden)

Romain Vullo

2016-12-01

Full Text Available Spinosaurs represent a group of peculiar theropod dinosaurs that have often been described as “crocodile-mimic”, predominantly fish-eating predators, and recently claimed to have been semi-aquatic animals. Here we report a suite of craniodental characters unexpectedly shared by spinosaurs and pike conger eels. Pike conger eels are predatory, mainly piscivorous bottom-dwelling anguilliform fishes that inhabit marine and brackish environments. These two groups of dinosaurs and fishes show a mediolaterally compressed, elongated rostrum, a terminal “rosette” bearing enlarged teeth in both upper and lower jaws, and a notch posterior to the premaxillary “rosette” characterized by the presence of reduced teeth. The morphological convergence observed in the jaws of these two distantly related groups of vertebrates may result from similar feeding behaviours. This typical jaw morphology likely represents an effective biomechanical adaptation for biting and grabbing elusive prey items in low-light aquatic environments. Associated with this specialized snout morphology, numerous integumentary mechanoreceptors involved in prey detection are present in both spinosaurs and pike congers. Our new observations provide an additional convincing argument regarding the decades-long and widely debated lifestyle of spinosaurs.

Differences between Experts' and Students' Conceptual Images of the Mathematical Structure of Taylor Series Convergence

Science.gov (United States)

Martin, Jason

2013-01-01

Taylor series convergence is a complicated mathematical structure which incorporates multiple concepts. Therefore, it can be very difficult for students to initially comprehend. How might students make sense of this structure? How might experts make sense of this structure? To answer these questions, an exploratory study was conducted using…

Comparison of Multiple-Microphone and Single-Loudspeaker Adaptive Feedback/Echo Cancellation Systems

DEFF Research Database (Denmark)

Guo, Meng; Elmedyb, Thomas Bo; Jensen, Søren Holdt

2011-01-01

Recently, we introduced a frequency domain measure - the power transfer function - to predict the convergence rate, system stability bound and the steady-state behavior across time and frequency of a least mean square based feedback/echo cancellation algorithm in a general multiple-microphone and......Recently, we introduced a frequency domain measure - the power transfer function - to predict the convergence rate, system stability bound and the steady-state behavior across time and frequency of a least mean square based feedback/echo cancellation algorithm in a general multiple...

Statistical convergence on intuitionistic fuzzy normed spaces

International Nuclear Information System (INIS)

Karakus, S.; Demirci, K.; Duman, O.

2008-01-01

Saadati and Park [Saadati R, Park JH, Chaos, Solitons and Fractals 2006;27:331-44] has recently introduced the notion of intuitionistic fuzzy normed space. In this paper, we study the concept of statistical convergence on intuitionistic fuzzy normed spaces. Then we give a useful characterization for statistically convergent sequences. Furthermore, we display an example such that our method of convergence is stronger than the usual convergence on intuitionistic fuzzy normed spaces

Systems of evolution equations and the singular perturbation method

International Nuclear Information System (INIS)

Mika, J.

Several fundamental theorems are presented important for the solution of linear evolution equations in the Banach space. The algorithm is deduced extending the solution of the system of singularly perturbed evolution equations into an asymptotic series with respect to a small positive parameter. The asymptotic convergence is shown of an approximate solution to the accurate solution. Singularly perturbed evolution equations of the resonance type were analysed. The special role is considered of the asymptotic equivalence of P1 equations obtained as the first order approximation if the spherical harmonics method is applied to the linear Boltzmann equation, and the diffusion equations of the linear transport theory where the small parameter approaches zero. (J.B.)

Cultura da Convergência

Directory of Open Access Journals (Sweden)

Rogério Christofoletti

2008-12-01

Full Text Available Três idéias já seriam suficientes para que a leitura de “Culturada Convergência”, de Henry Jenkins, interessasse a jornalistas epesquisadores da área: a convergência midiática como um processo cultural; o fortalecimento de uma economia afetiva que orienta consumidores de bens simbólicos e criadores midiáticos; a expansão de formas narrativas transmidiáticas.

Stimulating Creativity: Modulation of Convergent and Divergent Thinking by Transcranial Direct Current Stimulation (tDCS)

Science.gov (United States)

Zmigrod, Sharon; Colzato, Lorenza S.; Hommel, Bernhard

2015-01-01

Creativity has been conceptualized as involving 2 distinct components; divergent thinking, the search for multiple solutions to a single problem, and convergent thinking, the quest for a single solution either through an analytical process or the experience of insight. Studies have demonstrated that these abilities can be improved by cognitive…

Benign multiple sclerosis: physical and cognitive impairment follow distinct evolutions.

Science.gov (United States)

Gajofatto, A; Turatti, M; Bianchi, M R; Forlivesi, S; Gobbin, F; Azzarà, A; Monaco, S; Benedetti, M D

2016-03-01

Benign multiple sclerosis (BMS) definitions rely on physical disability level but do not account sufficiently for cognitive impairment which, however, is not rare. To study the evolution of physical disability and cognitive performance of a group of patients with BMS followed at an University Hospital Multiple Sclerosis Center. A consecutive sample of 24 BMS cases (diagnosis according to 2005 McDonald's criteria, relapsing-remitting course, disease duration ≥ 10 years, and expanded disability status scale [EDSS] score ≤ 2.0) and 13 sex- and age-matched non-BMS patients differing from BMS cases for having EDSS score 2.5-5.5 were included. Main outcome measures were as follows: (i) baseline and 5-year follow-up cognitive impairment defined as failure of at least two tests of the administered neuropsychological battery; (ii) EDSS score worsening defined as confirmed increase ≥ 1 point (or 0.5 point if baseline EDSS score = 5.5). At inclusion, BMS subjects were 41 ± 8 years old and had median EDSS score 1.5 (range 0-2), while non-BMS patients were 46 ± 8 years old and had median EDSS score 3.0 (2.5-5.5). At baseline 16% of patients in both groups were cognitively impaired. After 5 years, EDSS score worsened in 8% of BMS and 46% of non-BMS patients (P = 0.008), while the proportion of cognitively impaired subjects increased to 25% in both groups. Patients with BMS had better physical disability outcome at 5 years compared to non-BMS cases. However, cognitive impairment frequency and decline over time appeared similar. Neuropsychological assessment is essential in patients with BMS given the distinct pathways followed by disease progression in cognitive and physical domains. © 2015 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

Evolution of apoptosis-like programmed cell death in unicellular protozoan parasites.

Science.gov (United States)

Kaczanowski, Szymon; Sajid, Mohammed; Reece, Sarah E

2011-03-25

Apoptosis-like programmed cell death (PCD) has recently been described in multiple taxa of unicellular protists, including the protozoan parasites Plasmodium, Trypanosoma and Leishmania. Apoptosis-like PCD in protozoan parasites shares a number of morphological features with programmed cell death in multicellular organisms. However, both the evolutionary explanations and mechanisms involved in parasite PCD are poorly understood. Explaining why unicellular organisms appear to undergo 'suicide' is a challenge for evolutionary biology and uncovering death executors and pathways is a challenge for molecular and cell biology. Bioinformatics has the potential to integrate these approaches by revealing homologies in the PCD machinery of diverse taxa and evaluating their evolutionary trajectories. As the molecular mechanisms of apoptosis in model organisms are well characterised, and recent data suggest similar mechanisms operate in protozoan parasites, key questions can now be addressed. These questions include: which elements of apoptosis machinery appear to be shared between protozoan parasites and multicellular taxa and, have these mechanisms arisen through convergent or divergent evolution? We use bioinformatics to address these questions and our analyses suggest that apoptosis mechanisms in protozoan parasites and other taxa have diverged during their evolution, that some apoptosis factors are shared across taxa whilst others have been replaced by proteins with similar biochemical activities.

Kinematic evolution of the Romanian Carpathians

Science.gov (United States)

Linzer, Hans-Gert; Frisch, Wolfgang; Zweigel, Peter; Girbacea, Radu; Hann, Horst-Peter; Moser, Franz

1998-11-01

The regional pattern of contraction and extension directions and the evolution of the strain field from Paleogene to Neogene times enabled a reconstruction of the migration path of the Carpathian collision front. The Carpathian nappes were thrust around the Moesian Plate during Paleogene and Early Neogene times and protruded into a small oceanic embayment between the Moesian and European plates. The arc structure of the Carpathian fold-thrust belt was formed in Late Neogene times as a result of the eastward-escaping Tisza-Dacia block, due to N-directed convergence of the Adriatic plate and the retreating subduction of an oceanic slab. Brittle deformation structures in the Romanian Carpathians suggest three tectonic events related to major plate motions: (1) Paleogene to Middle Miocene NE to ENE contraction caused right-lateral curved strike-slip faults; (2) Middle Miocene to Pliocene fan-shaped orientations of contraction directions were caused by right-lateral oblique convergence in the Southern Carpathians, frontal convergence in the southern Eastern Carpathians and left-lateral convergence in the northern Eastern Carpathians; (3) Pleistocene to Holocene general E-W extension and N-S contraction in the Carpathian arc and local ESE-WNW contraction in the Vrancea area is related to the late roll back stage and break-off of the subducted slab in the bend area.

Spatial and Temporal Variations in Slip Partitioning During Oblique Convergence Experiments

Science.gov (United States)

Beyer, J. L.; Cooke, M. L.; Toeneboehn, K.

2017-12-01

Physical experiments of oblique convergence in wet kaolin demonstrate the development of slip partitioning, where two faults accommodate strain via different slip vectors. In these experiments, the second fault forms after the development of the first fault. As one strain component is relieved by one fault, the local stress field then favors the development of a second fault with different slip sense. A suite of physical experiments reveals three styles of slip partitioning development controlled by the convergence angle and presence of a pre-existing fault. In experiments with low convergence angles, strike-slip faults grow prior to reverse faults (Type 1) regardless of whether the fault is precut or not. In experiments with moderate convergence angles, slip partitioning is dominantly controlled by the presence of a pre-existing fault. In all experiments, the primarily reverse fault forms first. Slip partitioning then develops with the initiation of strike-slip along the precut fault (Type 2) or growth of a secondary reverse fault where the first fault is steepest. Subsequently, the slip on the first fault transitions to primarily strike-slip (Type 3). Slip rates and rakes along the slip partitioned faults for both precut and uncut experiments vary temporally, suggesting that faults in these slip-partitioned systems are constantly adapting to the conditions produced by slip along nearby faults in the system. While physical experiments show the evolution of slip partitioning, numerical simulations of the experiments provide information about both the stress and strain fields, which can be used to compute the full work budget, providing insight into the mechanisms that drive slip partitioning. Preliminary simulations of precut experiments show that strain energy density (internal work) can be used to predict fault growth, highlighting where fault growth can reduce off-fault deformation in the physical experiments. In numerical simulations of uncut experiments with a

Convergent systems vs. incremental stability

NARCIS (Netherlands)

Rüffer, B.S.; Wouw, van de N.; Mueller, M.

2013-01-01

Two similar stability notions are considered; one is the long established notion of convergent systems, the other is the younger notion of incremental stability. Both notions require that any two solutions of a system converge to each other. Yet these stability concepts are different, in the sense

Regional Convergence and Sustainable Development in China

Directory of Open Access Journals (Sweden)

Fang Yang

2016-01-01

Full Text Available Based on the convergence theory of economic growth, this paper extends this concept to the human development index and carries out an empirical analysis of regional development in China between 1997 and 2006. Our research shows that the conditional convergence has been identified. Investment in fixed assets, government expenditure on education, health and infrastructure construction have positive effects on regional convergence of social development. Population weighted analysis of human development index provides support for weak convergence amongst provinces. Analysis of dynamics of regional distribution reveals the club convergence, which indicate two different convergence states. Central China is in the shade and lags behind, giving rise to the so-called “central downfall”. To solve this problem, the “Rise of Central China” Plan is necessary to promote the connection between coastal and inland regions of China and reduce the regional development gap.

A Hybrid Multiobjective Differential Evolution Algorithm and Its Application to the Optimization of Grinding and Classification

Directory of Open Access Journals (Sweden)

Yalin Wang

2013-01-01

Full Text Available The grinding-classification is the prerequisite process for full recovery of the nonrenewable minerals with both production quality and quantity objectives concerned. Its natural formulation is a constrained multiobjective optimization problem of complex expression since the process is composed of one grinding machine and two classification machines. In this paper, a hybrid differential evolution (DE algorithm with multi-population is proposed. Some infeasible solutions with better performance are allowed to be saved, and they participate randomly in the evolution. In order to exploit the meaningful infeasible solutions, a functionally partitioned multi-population mechanism is designed to find an optimal solution from all possible directions. Meanwhile, a simplex method for local search is inserted into the evolution process to enhance the searching strategy in the optimization process. Simulation results from the test of some benchmark problems indicate that the proposed algorithm tends to converge quickly and effectively to the Pareto frontier with better distribution. Finally, the proposed algorithm is applied to solve a multiobjective optimization model of a grinding and classification process. Based on the technique for order performance by similarity to ideal solution (TOPSIS, the satisfactory solution is obtained by using a decision-making method for multiple attributes.

Genetic convergence in the adaptation of dogs and humans to the high-altitude environment of the tibetan plateau.

Science.gov (United States)

Wang, Guo-Dong; Fan, Ruo-Xi; Zhai, Weiwei; Liu, Fei; Wang, Lu; Zhong, Li; Wu, Hong; Yang, He-Chuan; Wu, Shi-Fang; Zhu, Chun-Ling; Li, Yan; Gao, Yun; Ge, Ri-Li; Wu, Chung-I; Zhang, Ya-Ping

2014-08-01

The high-altitude hypoxic environment represents one of the most extreme challenges for mammals. Previous studies of humans on the Tibetan plateau and in the Andes Mountains have identified statistical signatures of selection in different sets of loci. Here, we first measured the hemoglobin levels in village dogs from Tibet and those from Chinese lowlands. We found that the hemoglobin levels are very similar between the two groups, suggesting that Tibetan dogs might share similar adaptive strategies as the Tibetan people. Through a whole-genome sequencing approach, we have identified EPAS1 and HBB as candidate genes for the hypoxic adaptation on the Tibetan plateau. The population genetic analysis shows a significant convergence between humans and dogs in Tibet. The similarities in the sets of loci that exhibit putative signatures of selection and the hemoglobin levels between humans and dogs of the same environment, but not between human populations in different regions, suggests an extraordinary landscape of convergent evolution between human beings and their best friend on the Tibetan plateau. © The Author(s) 2014. Published by Oxford University Press on behalf of the Society for Molecular Biology and Evolution.

Convergence as conditionant for Media Regulation

Directory of Open Access Journals (Sweden)

Othon Jambeiro

2011-01-01

Full Text Available Convergence comprises a combination of interlinked and interdependent transformations, of technological, industrial, commercial, cultural and social nature, which affect communication regulation. Customers, at their time, turned also convergent, involved in an intense participative culture, which is too, from the point of view of its social and geographical range, thanks to convergence, more and more extense. Instead of passive consumers of media and information and communication services, we have now active and socially connected consumers, no more readers/spectators/listeners, but noisy activists and publishers. To understand this phenomenon is essential to discern a regulatory frame suitable for it. This paper tries to define convergence and to discuss its consequences.

Cultura da Convergência

Directory of Open Access Journals (Sweden)

Rogério Christofoletti

2008-12-01

Full Text Available Três idéias já seriam suficientes para que a leitura de “Cultura da Convergência”, de Henry Jenkins, interessasse a jornalistas e pesquisadores da área: a convergência midiática como um processo cultural; o fortalecimento de uma economia afetiva que orienta consumidores de bens simbólicos e criadores midiáticos; a expansão de formas narrativas transmidiáticas.

Convergence of barycentric coordinates to barycentric kernels

KAUST Repository

Kosinka, Jiří

2016-02-12

We investigate the close correspondence between barycentric coordinates and barycentric kernels from the point of view of the limit process when finer and finer polygons converge to a smooth convex domain. We show that any barycentric kernel is the limit of a set of barycentric coordinates and prove that the convergence rate is quadratic. Our convergence analysis extends naturally to barycentric interpolants and mappings induced by barycentric coordinates and kernels. We verify our theoretical convergence results numerically on several examples.

Convergence of barycentric coordinates to barycentric kernels

KAUST Repository

Kosinka, Jiří ; Barton, Michael

2016-01-01

We investigate the close correspondence between barycentric coordinates and barycentric kernels from the point of view of the limit process when finer and finer polygons converge to a smooth convex domain. We show that any barycentric kernel is the limit of a set of barycentric coordinates and prove that the convergence rate is quadratic. Our convergence analysis extends naturally to barycentric interpolants and mappings induced by barycentric coordinates and kernels. We verify our theoretical convergence results numerically on several examples.

Converging cylindrical magnetohydrodynamic shock collapse onto a power-law-varying line current

KAUST Repository

Mostert, W.

2016-03-16

We investigate the convergence behaviour of a cylindrical, fast magnetohydrodynamic (MHD) shock wave in a neutrally ionized gas collapsing onto an axial line current that generates a power law in time, azimuthal magnetic field. The analysis is done within the framework of a modified version of ideal MHD for an inviscid, non-dissipative, neutrally ionized compressible gas. The time variation of the magnetic field is tuned such that it approaches zero at the instant that the shock reaches the axis. This configuration is motivated by the desire to produce a finite magnetic field at finite shock radius but a singular gas pressure and temperature at the instant of shock impact. Our main focus is on the variation with shock radius, as, of the shock Mach number and pressure behind the shock as a function of the magnetic field power-law exponent, where gives a constant-in-time line current. The flow problem is first formulated using an extension of geometrical shock dynamics (GSD) into the time domain to take account of the time-varying conditions ahead of the converging shock, coupled with appropriate shock-jump conditions for a fast, symmetric MHD shock. This provides a pair of ordinary differential equations describing both and the time evolution on the shock, as a function of, constrained by a collapse condition required to achieve tuned shock convergence. Asymptotic, analytical results for and are obtained over a range of for general, and for both small and large . In addition, numerical solutions of the GSD equations are performed over a large range of, for selected parameters using . The accuracy of the GSD model is verified for some cases using direct numerical solution of the full, radially symmetric MHD equations using a shock-capturing method. For the GSD solutions, it is found that the physical character of the shock convergence to the axis is a strong function of . For μ≤0.816, and both approach unity at shock impact owing to the dominance of the strong

Desafios globais contemporâneos: cenário de convergências no direito internacional Global contemporary challenges: convergences scenario in international law

Directory of Open Access Journals (Sweden)

Ely Caetano Xavier Junior

2009-12-01

Full Text Available O cenário internacional contemporâneo é caracterizado por uma multiplicidade de agentes e interesses, gerando uma complexa teia de relações econômicas, sociais e jurídicas. os desafios globais representados pelas inéditas relações exigem respostas rápidas e eficientes por parte do direito. Essa jornada em busca das soluções para os conflitos emergentes do plano internacional requer uma releitura do significado da divisão entre as esferas pública e privada do direito. Seja através do crescimento dos fundos soberanos de riqueza, que traz à luz uma série de novos paradigmas no campo econômico, sobretudo a convergência entre o papel do estado e o papel do investidor internacional; seja através do encontro entre a necessidade de proteção aos direitos humanos e a harmonização do sistema multilateral de comércio internacional; seja através das interseções entre a governança global e a tutela dos direitos difusos, o direito internacional certamente caminha para a convergência.The contemporary international scenario is characterized by a multiplicity of actors and interests, creating a complex web of economic, social and legal relationships. The challenges represented by these new relationships need rapid and efficient responses by law. This journey seeking the solutions to the conflicts arising from the international arena requires a reassessment of the meaning of the division between public and private spheres of law. Through the growth of sovereign wealth funds, which arises several new paradigms in the economic field, noticeably the convergence between the role of the state and the role of the international investor; through the encounter between the necessity to protect human rights and harmonize the multilateral international trade system, or through the intersections between global governance and the protection of diffuse rights, international law is certainly moving towards the convergence.

Towards a Universal Biology: Is the Origin and Evolution of Life Predictable?

Science.gov (United States)

Rothschild, Lynn J.

2017-01-01

The origin and evolution of life seems an unpredictable oddity, based on the quirks of contingency. Celebrated by the late Stephen Jay Gould in several books, "evolution by contingency" has all the adventure of a thriller, but lacks the predictive power of the physical sciences. Not necessarily so, replied Simon Conway Morris, for convergence reassures us that certain evolutionary responses are replicable. The outcome of this debate is critical to Astrobiology. How can we understand where we came from on Earth without prophesy? Further, we cannot design a rational strategy for the search for life elsewhere - or to understand what the future will hold for life on Earth and beyond - without extrapolating from pre-biotic chemistry and evolution. There are several indirect approaches to understanding, and thus describing, what life must be. These include philosophical approaches to defining life (is there even a satisfactory definition of life?), using what we know of physics, chemistry and life to imagine alternate scenarios, using different approaches that life takes as pseudoreplicates (e.g., ribosomal vs non-ribosomal protein synthesis), and experimental approaches to understand the art of the possible. Given that: (1) Life is a process based on physical components rather than simply an object; (2). Life is likely based on organic carbon and needs a solvent for chemistry, most likely water, and (3) Looking for convergence in terrestrial evolution we can predict certain tendencies, if not quite "laws", that provide predictive power. Biological history must obey the laws of physics and chemistry, the principles of natural selection, the constraints of an evolutionary past, genetics, and developmental biology. This amalgam creates a surprising amount of predictive power in the broad outline. Critical is the apparent prevalence of organic chemistry, and uniformity in the universe of the laws of chemistry and physics. Instructive is the widespread occurrence of

Δim-lacunary statistical convergence of order α

Science.gov (United States)

Altınok, Hıfsı; Et, Mikail; Işık, Mahmut

2018-01-01

The purpose of this work is to introduce the concepts of Δim-lacunary statistical convergence of order α and lacunary strongly (Δim,p )-convergence of order α. We establish some connections between lacunary strongly (Δim,p )-convergence of order α and Δim-lacunary statistical convergence of order α. It is shown that if a sequence is lacunary strongly (Δim,p )-summable of order α then it is Δim-lacunary statistically convergent of order α.

Increasing dominance of IT in ICT convergence

DEFF Research Database (Denmark)

Henten, Anders; Tadayoni, Reza

The aim of the paper is to examine the increasing dominance of IT companies in the converging ICT industry and, on the basis of this development, to contribute to extending the theoretical understanding of market and industry convergence in the ICT area.......The aim of the paper is to examine the increasing dominance of IT companies in the converging ICT industry and, on the basis of this development, to contribute to extending the theoretical understanding of market and industry convergence in the ICT area....

Strategic business transformation through technology convergence

DEFF Research Database (Denmark)

Agarwal, Nivedita; Brem, Alexander

2015-01-01

-time intelligence. This paper presents the case of General Electric (GE) and studies the various transitional phases and transformation dimensions that GE is experiencing, to manage this technology convergence. The evaluation of GE's experience indicates that convergence-related business transformation is nonlinear......Technology adoption is crucial for an organisation to remain competitive in the marketplace. Traditionally, two technologies - operational technology (OT) and information technology (IT) - have operated independently from one another; however, technological advancements that businesses...... are experiencing have increased the overlap and convergence of these two areas. Industrial organisations are investing heavily in the integration and alignment of these technologies and expect to benefit in several ways from this convergence, such as through increased productivity, reduction in cost, and real...

Fixed mobile convergence handbook

CERN Document Server

Ahson, Syed A

2010-01-01

From basic concepts to future directions, this handbook provides technical information on all aspects of fixed-mobile convergence (FMC). The book examines such topics as integrated management architecture, business trends and strategic implications for service providers, personal area networks, mobile controlled handover methods, SIP-based session mobility, and supervisory and notification aggregator service. Case studies are used to illustrate technical and systematic implementation of unified and rationalized internet access by fixed-mobile network convergence. The text examines the technolo

A Globally Convergent Matrix-Free Method for Constrained Equations and Its Linear Convergence Rate

Directory of Open Access Journals (Sweden)

Min Sun

2014-01-01

Full Text Available A matrix-free method for constrained equations is proposed, which is a combination of the well-known PRP (Polak-Ribière-Polyak conjugate gradient method and the famous hyperplane projection method. The new method is not only derivative-free, but also completely matrix-free, and consequently, it can be applied to solve large-scale constrained equations. We obtain global convergence of the new method without any differentiability requirement on the constrained equations. Compared with the existing gradient methods for solving such problem, the new method possesses linear convergence rate under standard conditions, and a relax factor γ is attached in the update step to accelerate convergence. Preliminary numerical results show that it is promising in practice.

"Nanoselves": NBIC and the Culture of Convergence

Science.gov (United States)

Venkatesan, Priya

2010-01-01

The subject of this essay is NBIC convergence (nanotechnology, biotechnology, information technology and cognitive science convergence). NBIC convergence is a recurring trope that is dominated by the paradigm of integration of the sciences. It is largely influenced by the considerations of social and economic impact, and it assumes positivism in…

Sectoral Energy, and Labour, Productivity Convergence

International Nuclear Information System (INIS)

Mulder, P.; De Groot, H.L.F.

2007-01-01

This paper empirically investigates the development of cross-country differences in energy- and labour productivity. The analysis is performed at a detailed sectoral level for 14 OECD countries, covering the period 1970-1997. A ρ-convergence analysis reveals that the development over time of the cross-country variation in productivity performance differs across sectors as well as across different levels of aggregation. Both patterns of convergence as well as divergence are found. Cross-country variation of productivity levels is typically larger for energy than for labour. A β-convergence analysis provides support for the hypothesis that in most sectors lagging countries tend to catch up with technological leaders, in particular in terms of energy productivity. Moreover, the results show that convergence is conditional, meaning that productivity levels converge to country-specific steady states. Energy prices and wages are shown to positively affect energy- and labour-productivity growth, respectively. We also find evidence for the importance of economies of scale, whereas the investment share, openness and specialization play only a modest role in explaining cross-country variation in energy- and labour-productivity growth

Convergence Insufficiency

Science.gov (United States)

... is also found to be weak. If both accommodation and convergence are weak, reading glasses, sometimes with prism added, may be a great option for these patients. It is very difficult to improve accommodation with exercises. Updated 7/2017 Eye Terms & Conditions ...

Convergence theorems for Banach space valued integrable multifunctions

Directory of Open Access Journals (Sweden)

Nikolaos S. Papageorgiou

1987-01-01

Full Text Available In this work we generalize a result of Kato on the pointwise behavior of a weakly convergent sequence in the Lebesgue-Bochner spaces LXP(Ω (1≤p≤∞. Then we use that result to prove Fatou's type lemmata and dominated convergence theorems for the Aumann integral of Banach space valued measurable multifunctions. Analogous convergence results are also proved for the sets of integrable selectors of those multifunctions. In the process of proving those convergence theorems we make some useful observations concerning the Kuratowski-Mosco convergence of sets.

Weak convergence and uniform normalization in infinitary rewriting

DEFF Research Database (Denmark)

Simonsen, Jakob Grue

2010-01-01

the starkly surprising result that for any orthogonal system with finitely many rules, the system is weakly normalizing under weak convergence if{f} it is strongly normalizing under weak convergence if{f} it is weakly normalizing under strong convergence if{f} it is strongly normalizing under strong...... convergence. As further corollaries, we derive a number of new results for weakly convergent rewriting: Systems with finitely many rules enjoy unique normal forms, and acyclic orthogonal systems are confluent. Our results suggest that it may be possible to recover some of the positive results for strongly...

Multiple-Features-Based Semisupervised Clustering DDoS Detection Method

Directory of Open Access Journals (Sweden)

Yonghao Gu

2017-01-01

Full Text Available DDoS attack stream from different agent host converged at victim host will become very large, which will lead to system halt or network congestion. Therefore, it is necessary to propose an effective method to detect the DDoS attack behavior from the massive data stream. In order to solve the problem that large numbers of labeled data are not provided in supervised learning method, and the relatively low detection accuracy and convergence speed of unsupervised k-means algorithm, this paper presents a semisupervised clustering detection method using multiple features. In this detection method, we firstly select three features according to the characteristics of DDoS attacks to form detection feature vector. Then, Multiple-Features-Based Constrained-K-Means (MF-CKM algorithm is proposed based on semisupervised clustering. Finally, using MIT Laboratory Scenario (DDoS 1.0 data set, we verify that the proposed method can improve the convergence speed and accuracy of the algorithm under the condition of using a small amount of labeled data sets.

Electricity and gas : market and price convergence : fundamentals of restructuring and convergence

Energy Technology Data Exchange (ETDEWEB)

Heintz, H.; Spragins, R.

2000-07-01

One of the results of the transition from regulation to competition in the Canadian and American natural gas and electricity industries is convergence of the two industries. Convergence is occurring in the areas of corporate structuring activities (mergers and acquisitions), natural gas and electricity prices, products and services, and on a geographic basis. This study examines the restructuring and convergence from the perspective of industry stakeholders, consumers, competitors and regulators. The trend to deregulate to establish competitive markets has been driven by the assumption that lower prices and more choices will result. Deregulation has been made easier by technological developments and innovations in the area of conventional generation, distributed generation, information management and analysis, as well as mass communication channels such as the Internet. These changes have made it possible to measure and monitor energy use in real-time. Technological changes will continue to influence the energy industry. The use of different restructuring rules and regulations in jurisdictions that are implementing change may be one of the primary factors that could limit the extent of convergence. Successful competition by energy service providers in converged retail energy markets will depend on several factors, the first of which is the ability to control the customer interface through retail cycle services such as metering and billing. The second is the successful branding of corporate identities, products and services. These will ensure customer loyalty and facilitate the marketing of new products. Another factor would be the effective management of information regarding natural gas and electricity consumption patterns and the establishment of low cost operations through the use of conventional generation technologies. The final factor for successful competition is the effective use of low cost communication technologies such as the Internet. The transition

Electricity and gas : market and price convergence : fundamentals of restructuring and convergence

International Nuclear Information System (INIS)

Heintz, H.; Spragins, R.

2000-01-01

One of the results of the transition from regulation to competition in the Canadian and American natural gas and electricity industries is convergence of the two industries. Convergence is occurring in the areas of corporate structuring activities (mergers and acquisitions), natural gas and electricity prices, products and services, and on a geographic basis. This study examines the restructuring and convergence from the perspective of industry stakeholders, consumers, competitors and regulators. The trend to deregulate to establish competitive markets has been driven by the assumption that lower prices and more choices will result. Deregulation has been made easier by technological developments and innovations in the area of conventional generation, distributed generation, information management and analysis, as well as mass communication channels such as the Internet. These changes have made it possible to measure and monitor energy use in real-time. Technological changes will continue to influence the energy industry. The use of different restructuring rules and regulations in jurisdictions that are implementing change may be one of the primary factors that could limit the extent of convergence. Successful competition by energy service providers in converged retail energy markets will depend on several factors, the first of which is the ability to control the customer interface through retail cycle services such as metering and billing. The second is the successful branding of corporate identities, products and services. These will ensure customer loyalty and facilitate the marketing of new products. Another factor would be the effective management of information regarding natural gas and electricity consumption patterns and the establishment of low cost operations through the use of conventional generation technologies. The final factor for successful competition is the effective use of low cost communication technologies such as the Internet. The transition

Trophic specialization drives morphological evolution in sea snakes.

Science.gov (United States)

Sherratt, Emma; Rasmussen, Arne R; Sanders, Kate L

2018-03-01

Viviparous sea snakes are the most rapidly speciating reptiles known, yet the ecological factors underlying this radiation are poorly understood. Here, we reconstructed dated trees for 75% of sea snake species and quantified body shape (forebody relative to hindbody girth), maximum body length and trophic diversity to examine how dietary specialization has influenced morphological diversification in this rapid radiation. We show that sea snake body shape and size are strongly correlated with the proportion of burrowing prey in the diet. Specialist predators of burrowing eels have convergently evolved a 'microcephalic' morphotype with dramatically reduced forebody relative to hindbody girth and intermediate body length. By comparison, snakes that predominantly feed on burrowing gobies are generally short-bodied and small-headed, but there is no evidence of convergent evolution. The eel specialists also exhibit faster rates of size and shape evolution compared to all other sea snakes, including those that feed on gobies. Our results suggest that trophic specialization to particular burrowing prey (eels) has invoked strong selective pressures that manifest as predictable and rapid morphological changes. Further studies are needed to examine the genetic and developmental mechanisms underlying these dramatic morphological changes and assess their role in sea snake speciation.

Convergent occurrence of the developmental hourglass in plant and animal embryogenesis?

Science.gov (United States)

Cridge, Andrew G; Dearden, Peter K; Brownfield, Lynette R

2016-04-01

The remarkable similarity of animal embryos at particular stages of development led to the proposal of a developmental hourglass. In this model, early events in development are less conserved across species but lead to a highly conserved 'phylotypic period'. Beyond this stage, the model suggests that development once again becomes less conserved, leading to the diversity of forms. Recent comparative studies of gene expression in animal groups have provided strong support for the hourglass model. How and why might such an hourglass pattern be generated? More importantly, how might early acting events in development evolve while still maintaining a later conserved stage? The discovery that an hourglass pattern may also exist in the embryogenesis of plants provides comparative data that may help us explain this phenomenon. Whether the developmental hourglass occurs in plants, and what this means for our understanding of embryogenesis in plants and animals is discussed. Models by which conserved early-acting genes might change their functional role in the evolution of gene networks, how networks buffer these changes, and how that might constrain, or confer diversity, of the body plan are also discused. Evidence of a morphological and molecular hourglass in plant and animal embryogenesis suggests convergent evolution. This convergence is likely due to developmental constraints imposed upon embryogenesis by the need to produce a viable embryo with an established body plan, controlled by the architecture of the underlying gene regulatory networks. As the body plan is largely laid down during the middle phases of embryo development in plants and animals, then it is perhaps not surprising this stage represents the narrow waist of the hourglass where the gene regulatory networks are the oldest and most robust and integrated, limiting species diversity and constraining morphological space. © The Author 2016. Published by Oxford University Press on behalf of the Annals of

Some approximating formulae to the solution of an abstract evolution problem

International Nuclear Information System (INIS)

Ngongo, M.E.

1991-12-01

We consider discrete semigroups of operators associated with the first two primary sub-families of A-acceptable Norsett's rational approximations to e q , S 1 (γ;q) and S 2 (γ;q) with q is an element of C and γ a real parameter, and construct approximating formulae to the solution of an abstract evolution problem. The study of convergence is reduced to exploiting previous fundamental results of the author for this class of semigroups and this results, for associated numerical schemes, in a convergence independent of the regularity of the data of the problem. (author). 17 refs, 3 tabs

Co-existence of multiple trade-off currencies shapes evolutionary outcomes.

Directory of Open Access Journals (Sweden)

Alan A Cohen

Full Text Available Evolutionary studies often assume that energy is the primary resource (i.e. "currency" at the heart of the survival-reproduction trade-off, despite recent evidence to the contrary. The evolutionary consequences of having a single trade-off currency versus multiple competing currencies are unknown. Using simulations, we modeled the evolution of either a single physiological currency between reproduction and survival, or of multiple such currencies. For a wide array of model specifications varying functional forms and strengths of the trade-offs, we show that the presence of multiple currencies (e.g. nutrients, time generally results in the evolution of higher lifetime reproductive success through partial circumvention of such trade-offs. Evolution of the underlying physiology is also more highly contingent with multiple currencies. These results challenge the paradigm of a single survival-reproduction trade-off as central to life history evolution, suggesting greater roles for physiological constraints and contingency, and implying potential selection for evolution of multiple trade-off currencies.

Co-existence of multiple trade-off currencies shapes evolutionary outcomes

Science.gov (United States)

Isaksson, Caroline; Salguero-Gómez, Roberto

2017-01-01

Evolutionary studies often assume that energy is the primary resource (i.e. “currency”) at the heart of the survival-reproduction trade-off, despite recent evidence to the contrary. The evolutionary consequences of having a single trade-off currency versus multiple competing currencies are unknown. Using simulations, we modeled the evolution of either a single physiological currency between reproduction and survival, or of multiple such currencies. For a wide array of model specifications varying functional forms and strengths of the trade-offs, we show that the presence of multiple currencies (e.g. nutrients, time) generally results in the evolution of higher lifetime reproductive success through partial circumvention of such trade-offs. Evolution of the underlying physiology is also more highly contingent with multiple currencies. These results challenge the paradigm of a single survival-reproduction trade-off as central to life history evolution, suggesting greater roles for physiological constraints and contingency, and implying potential selection for evolution of multiple trade-off currencies. PMID:29216275

Real parameter optimization by an effective differential evolution algorithm

Directory of Open Access Journals (Sweden)

Ali Wagdy Mohamed

2013-03-01

Full Text Available This paper introduces an Effective Differential Evolution (EDE algorithm for solving real parameter optimization problems over continuous domain. The proposed algorithm proposes a new mutation rule based on the best and the worst individuals among the entire population of a particular generation. The mutation rule is combined with the basic mutation strategy through a linear decreasing probability rule. The proposed mutation rule is shown to promote local search capability of the basic DE and to make it faster. Furthermore, a random mutation scheme and a modified Breeder Genetic Algorithm (BGA mutation scheme are merged to avoid stagnation and/or premature convergence. Additionally, the scaling factor and crossover of DE are introduced as uniform random numbers to enrich the search behavior and to enhance the diversity of the population. The effectiveness and benefits of the proposed modifications used in EDE has been experimentally investigated. Numerical experiments on a set of bound-constrained problems have shown that the new approach is efficient, effective and robust. The comparison results between the EDE and several classical differential evolution methods and state-of-the-art parameter adaptive differential evolution variants indicate that the proposed EDE algorithm is competitive with , and in some cases superior to, other algorithms in terms of final solution quality, efficiency, convergence rate, and robustness.

Late Cretaceous to Present evolution of the NW Africa peri-cratonic in the Africa-Eurasia plate convergence context

Science.gov (United States)

Ghorbal, B.; Bertotti, G.; Andriessen, P. A. M.

2009-04-01

Africa-Eurasia plate convergence is the main mechanism to explain topographic evolution and patterns of Tertiary vertical motions recorded around the entire Mediterranean and even further east. However, most of the studies are concentrated on the Eurasian side of the Mediterranean Realm. Along the NW Africa pericratonic zone (western Mediterranean side) extending longitudinally from the Anti-Atlas to the Rif Mountains, the highest topography is observed in the High Atlas intracontinental belt and in the Pan-African Anti-Atlas belt, and not in the youngest belt, the Rif. The combination of AFT and (U-Th)/He low-thermal dating, performed on pre-Cenozoic basement rocks along the Moroccan pericratonic transect (500km) yield ages ranging respectively between 90-9Ma and 65-7Ma, documenting vertical motions of subsidence and exhumation in between Late Cretaceous and Present. Time-Temperature models show that vertical movements are spatially zoned through Morocco, with the highest amplitude of vertical movements in the High Atlas (>4-5km) and more modest amounts in the Anti-Atlas and the Western Meseta (African peri-cratonic zone including the Western Meseta and the Anti-Atlas in addition to the Atlas and the Rif systems experienced Tertiary deformation. Two stages of folding are distinguished on the basis of low-thermal dating results along the pericratonic transect. The first is a lithospherical folding of ~500km in the Late Cretaceous (confirming that this process is a primary response to recently induced compressional stress fields) and the second is a crustal folding of ~100-150km wavelength in the Late Eocene that occurred independently to the mantle, requiring therefore the existence of a decoupling in between the base of the crust and the high mantle.

Quadratically convergent MCSCF scheme using Fock operators

International Nuclear Information System (INIS)

Das, G.

1981-01-01

A quadratically convergent formulation of the MCSCF method using Fock operators is presented. Among its advantages the present formulation is quadratically convergent unlike the earlier ones based on Fock operators. In contrast to other quadratically convergent schemes as well as the one based on generalized Brillouin's theorem, this method leads easily to a hybrid scheme where the weakly coupled orbitals (such as the core) are handled purely by Fock equations, while the rest of the orbitals are treated by a quadratically convergent approach with a truncated virtual space obtained by the use of the corresponding Fock equations

Multiple travelling wave solutions of nonlinear evolution equations using a unified algebraic method

International Nuclear Information System (INIS)

Fan Engui

2002-01-01

A new direct and unified algebraic method for constructing multiple travelling wave solutions of general nonlinear evolution equations is presented and implemented in a computer algebraic system. Compared with most of the existing tanh methods, the Jacobi elliptic function method or other sophisticated methods, the proposed method not only gives new and more general solutions, but also provides a guideline to classify the various types of the travelling wave solutions according to the values of some parameters. The solutions obtained in this paper include (a) kink-shaped and bell-shaped soliton solutions, (b) rational solutions, (c) triangular periodic solutions and (d) Jacobi and Weierstrass doubly periodic wave solutions. Among them, the Jacobi elliptic periodic wave solutions exactly degenerate to the soliton solutions at a certain limit condition. The efficiency of the method can be demonstrated on a large variety of nonlinear evolution equations such as those considered in this paper, KdV-MKdV, Ito's fifth MKdV, Hirota, Nizhnik-Novikov-Veselov, Broer-Kaup, generalized coupled Hirota-Satsuma, coupled Schroedinger-KdV, (2+1)-dimensional dispersive long wave, (2+1)-dimensional Davey-Stewartson equations. In addition, as an illustrative sample, the properties of the soliton solutions and Jacobi doubly periodic solutions for the Hirota equation are shown by some figures. The links among our proposed method, the tanh method, extended tanh method and the Jacobi elliptic function method are clarified generally. (author)

A replica exchange transition interface sampling method with multiple interface sets for investigating networks of rare events

Science.gov (United States)

Swenson, David W. H.; Bolhuis, Peter G.

2014-07-01

The multiple state transition interface sampling (TIS) framework in principle allows the simulation of a large network of complex rare event transitions, but in practice suffers from convergence problems. To improve convergence, we combine multiple state TIS [J. Rogal and P. G. Bolhuis, J. Chem. Phys. 129, 224107 (2008)] with replica exchange TIS [T. S. van Erp, Phys. Rev. Lett. 98, 268301 (2007)]. In addition, we introduce multiple interface sets, which allow more than one order parameter to be defined for each state. We illustrate the methodology on a model system of multiple independent dimers, each with two states. For reaction networks with up to 64 microstates, we determine the kinetics in the microcanonical ensemble, and discuss the convergence properties of the sampling scheme. For this model, we find that the kinetics depend on the instantaneous composition of the system. We explain this dependence in terms of the system's potential and kinetic energy.

Convergent Balancing Selection on an Antimicrobial Peptide in Drosophila.

Science.gov (United States)

Unckless, Robert L; Howick, Virginia M; Lazzaro, Brian P

2016-01-25

Genes of the immune system often evolve rapidly and adaptively, presumably driven by antagonistic interactions with pathogens [1-4]. Those genes encoding secreted antimicrobial peptides (AMPs), however, have failed to exhibit conventional signatures of strong adaptive evolution, especially in arthropods (e.g., [5, 6]) and often segregate for null alleles and gene deletions [3, 4, 7, 8]. Furthermore, quantitative genetic studies have failed to associate naturally occurring polymorphism in AMP genes with variation in resistance to infection [9-11]. Both the lack of signatures of positive selection in AMPs and lack of association between genotype and immune phenotypes have yielded an interpretation that AMP genes evolve under relaxed evolutionary constraint, with enough functional redundancy that variation in, or even loss of, any particular peptide would have little effect on overall resistance [12, 13]. In stark contrast to the current paradigm, we identified a naturally occurring amino acid polymorphism in the AMP Diptericin that is highly predictive of resistance to bacterial infection in Drosophila melanogaster [13]. The identical amino acid polymorphism arose in parallel in the sister species D. simulans, by independent mutation with equivalent phenotypic effect. Convergent substitutions at the same amino acid residue have evolved at least five times across the Drosophila genus. We hypothesize that the alternative alleles are maintained by balancing selection through context-dependent or fluctuating selection. This pattern of evolution appears to be common in AMPs but is invisible to conventional screens for adaptive evolution that are predicated on elevated rates of amino acid divergence. Copyright © 2016 Elsevier Ltd. All rights reserved.

a globally convergent hyperpl onvergent hyperplane

African Journals Online (AJOL)

userpc

Bayero Journal of Pure and App. ISSN 2006 – 6996 ... Globally Convergent Hyper plane-BFGS method for solving nonline. The attractive ... Numerical performance on some b rates there liability ..... convergence of a class of quasi methods on ...

The Landscape Evolution Observatory: a large-scale controllable infrastructure to study coupled Earth-surface processes

Science.gov (United States)

Pangle, Luke A.; DeLong, Stephen B.; Abramson, Nate; Adams, John; Barron-Gafford, Greg A.; Breshears, David D.; Brooks, Paul D.; Chorover, Jon; Dietrich, William E.; Dontsova, Katerina; Durcik, Matej; Espeleta, Javier; Ferré, T.P.A.; Ferriere, Regis; Henderson, Whitney; Hunt, Edward A.; Huxman, Travis E.; Millar, David; Murphy, Brendan; Niu, Guo-Yue; Pavao-Zuckerman, Mitch; Pelletier, Jon D.; Rasmussen, Craig; Ruiz, Joaquin; Saleska, Scott; Schaap, Marcel; Sibayan, Michael; Troch, Peter A.; Tuller, Markus; van Haren, Joost; Zeng, Xubin

2015-01-01

Zero-order drainage basins, and their constituent hillslopes, are the fundamental geomorphic unit comprising much of Earth's uplands. The convergent topography of these landscapes generates spatially variable substrate and moisture content, facilitating biological diversity and influencing how the landscape filters precipitation and sequesters atmospheric carbon dioxide. In light of these significant ecosystem services, refining our understanding of how these functions are affected by landscape evolution, weather variability, and long-term climate change is imperative. In this paper we introduce the Landscape Evolution Observatory (LEO): a large-scale controllable infrastructure consisting of three replicated artificial landscapes (each 330 m2 surface area) within the climate-controlled Biosphere 2 facility in Arizona, USA. At LEO, experimental manipulation of rainfall, air temperature, relative humidity, and wind speed are possible at unprecedented scale. The Landscape Evolution Observatory was designed as a community resource to advance understanding of how topography, physical and chemical properties of soil, and biological communities coevolve, and how this coevolution affects water, carbon, and energy cycles at multiple spatial scales. With well-defined boundary conditions and an extensive network of sensors and samplers, LEO enables an iterative scientific approach that includes numerical model development and virtual experimentation, physical experimentation, data analysis, and model refinement. We plan to engage the broader scientific community through public dissemination of data from LEO, collaborative experimental design, and community-based model development.

Local phylogenetic divergence and global evolutionary convergence of skull function in reef fishes of the family Labridae.

Science.gov (United States)

Westneat, Mark W; Alfaro, Michael E; Wainwright, Peter C; Bellwood, David R; Grubich, Justin R; Fessler, Jennifer L; Clements, Kendall D; Smith, Lydia L

2005-05-22

The Labridae is one of the most structurally and functionally diversified fish families on coral and rocky reefs around the world, providing a compelling system for examination of evolutionary patterns of functional change. Labrid fishes have evolved a diverse array of skull forms for feeding on prey ranging from molluscs, crustaceans, plankton, detritus, algae, coral and other fishes. The species richness and diversity of feeding ecology in the Labridae make this group a marine analogue to the cichlid fishes. Despite the importance of labrids to coastal reef ecology, we lack evolutionary analysis of feeding biomechanics among labrids. Here, we combine a molecular phylogeny of the Labridae with the biomechanics of skull function to reveal a broad pattern of repeated convergence in labrid feeding systems. Mechanically fast jaw systems have evolved independently at least 14 times from ancestors with forceful jaws. A repeated phylogenetic pattern of functional divergence in local regions of the labrid tree produces an emergent family-wide pattern of global convergence in jaw function. Divergence of close relatives, convergence among higher clades and several unusual 'breakthroughs' in skull function characterize the evolution of functional complexity in one of the most diverse groups of reef fishes.

An Improved Quantum-Behaved Particle Swarm Optimization Method for Economic Dispatch Problems with Multiple Fuel Options and Valve-Points Effects

Directory of Open Access Journals (Sweden)

Hong-Yun Zhang

2012-09-01

Full Text Available Quantum-behaved particle swarm optimization (QPSO is an efficient and powerful population-based optimization technique, which is inspired by the conventional particle swarm optimization (PSO and quantum mechanics theories. In this paper, an improved QPSO named SQPSO is proposed, which combines QPSO with a selective probability operator to solve the economic dispatch (ED problems with valve-point effects and multiple fuel options. To show the performance of the proposed SQPSO, it is tested on five standard benchmark functions and two ED benchmark problems, including a 40-unit ED problem with valve-point effects and a 10-unit ED problem with multiple fuel options. The results are compared with differential evolution (DE, particle swarm optimization (PSO and basic QPSO, as well as a number of other methods reported in the literature in terms of solution quality, convergence speed and robustness. The simulation results confirm that the proposed SQPSO is effective and reliable for both function optimization and ED problems.

The Mackey convergence condition for spaces with webs

Directory of Open Access Journals (Sweden)

Thomas E. Gilsdorf

1988-01-01

Full Text Available If each sequence converging to 0 in a locally convex space is also Mackey convergent to 0, that space is said to satisfy the Mackey convergence condition. The problem of characterizing those locally convex spaces with this property is still open. In this paper, spaces with compatible webs are used to construct both a necessary and a sufficient condition for a locally convex space to satisfy the Mackey convergence condition.

Convergent evolution of argonaute-2 slicer antagonism in two distinct insect RNA viruses.

NARCIS (Netherlands)

Mierlo, J.T. van; Bronkhorst, A.W.; Overheul, G.J.; Sadanandan, S.A.; Ekstrom, J.O.; Heestermans, M.; Hultmark, D.; Antoniewski, C.; Rij, R.P. van

2012-01-01

RNA interference (RNAi) is a major antiviral pathway that shapes evolution of RNA viruses. We show here that Nora virus, a natural Drosophila pathogen, is both a target and suppressor of RNAi. We detected viral small RNAs with a signature of Dicer-2 dependent small interfering RNAs in Nora virus

On the Fuzzy Convergence

Directory of Open Access Journals (Sweden)

Abdul Hameed Q. A. Al-Tai

2011-01-01

Full Text Available The aim of this paper is to introduce and study the fuzzy neighborhood, the limit fuzzy number, the convergent fuzzy sequence, the bounded fuzzy sequence, and the Cauchy fuzzy sequence on the base which is adopted by Abdul Hameed (every real number r is replaced by a fuzzy number r¯ (either triangular fuzzy number or singleton fuzzy set (fuzzy point. And then, we will consider that some results respect effect of the upper sequence on the convergent fuzzy sequence, the bounded fuzzy sequence, and the Cauchy fuzzy sequence.

On statistical acceleration convergence of double sequences

Directory of Open Access Journals (Sweden)

Bipan Hazarika

2017-04-01

Full Text Available In this article the notion of statistical acceleration convergence of double sequences in Pringsheim's sense has been introduced. We prove the decompostion theorems for  statistical acceleration convergence of double sequences and some theorems related to that concept have been established using the four dimensional matrix transformations. We provided some examples, where the results of acceleration convergence fails to hold for the statistical cases.

Convergence of carbon dioxide emissions in different sectors in China

International Nuclear Information System (INIS)

Wang, Juan; Zhang, Kezhong

2014-01-01

In this paper, we analyze differences in per capita carbon dioxide emissions from 1996 to 2010 in six sectors across 28 provinces in China and examine the σ-convergence, stochastic convergence and β-convergence of these emissions. We also investigate the factors that impact the convergence of per capita carbon dioxide emissions in each sector. The results show that per capita carbon dioxide emissions in all sectors converged across provinces from 1996 to 2010. Factors that impact the convergence of per capita carbon dioxide emissions in each sector vary: GDP (gross domestic product) per capita, industrialization process and population density impact convergence in the Industry sector, while GDP per capita and population density impact convergence in the Transportation, Storage, Postal, and Telecommunications Services sector. Aside from GDP per capita and population density, trade openness also impacts convergence in the Wholesale, Retail, Trade, and Catering Service sector. Population density is the only factor that impacts convergence in the Residential Consumption sector. - Highlights: • Analyze differences in CO 2 emissions in six sectors among 28 provinces in China. • Examine the convergence of CO 2 emissions in six sectors. • Investigate factors impact on convergence of CO 2 emissions in each sector. • Factors impact on convergence of per capita CO 2 emissions in each sector vary

Converging intracranial markers of conscious access.

Directory of Open Access Journals (Sweden)

Raphaël Gaillard

2009-03-01

Full Text Available We compared conscious and nonconscious processing of briefly flashed words using a visual masking procedure while recording intracranial electroencephalogram (iEEG in ten patients. Nonconscious processing of masked words was observed in multiple cortical areas, mostly within an early time window (<300 ms, accompanied by induced gamma-band activity, but without coherent long-distance neural activity, suggesting a quickly dissipating feedforward wave. In contrast, conscious processing of unmasked words was characterized by the convergence of four distinct neurophysiological markers: sustained voltage changes, particularly in prefrontal cortex, large increases in spectral power in the gamma band, increases in long-distance phase synchrony in the beta range, and increases in long-range Granger causality. We argue that all of those measures provide distinct windows into the same distributed state of conscious processing. These results have a direct impact on current theoretical discussions concerning the neural correlates of conscious access.

Quantifying convergence in the sciences

Directory of Open Access Journals (Sweden)

Sara Lumbreras

2016-02-01

Full Text Available Traditional epistemological models classify knowledge into separate disciplines with different objects of study and specific techniques, with some frameworks even proposing hierarchies (such as Comte’s. According to thinkers such as John Holland or Teilhard de Chardin, the advancement of science involves the convergence of disciplines. This proposed convergence can be studied in a number of ways, such as how works impact research outside a specific area (citation networks or how authors collaborate with other researchers in different fields (collaboration networks. While these studies are delivering significant new insights, they cannot easily show the convergence of different topics within a body of knowledge. This paper attempts to address this question in a quantitative manner, searching for evidence that supports the idea of convergence in the content of the sciences themselves (that is, whether the sciences are dealing with increasingly the same topics. We use Latent Dirichlet Analysis (LDA, a technique that is able to analyze texts and estimate the relative contributions of the topics that were used to generate them. We apply this tool to the corpus of the Santa Fe Institute (SFI working papers, which spans research on Complexity Science from 1989 to 2015. We then analyze the relatedness of the different research areas, the rise and demise of these sub-disciplines over time and, more broadly, the convergence of the research body as a whole. Combining the topic structure obtained from the collected publication history of the SFI community with techniques to infer hierarchy and clustering, we reconstruct a picture of a dynamic community which experiences trends, periodically recurring topics, and shifts in the closeness of scholarship over time. We find that there is support for convergence, and that the application of quantitative methods such as LDA to the study of knowledge can provide valuable insights that can help

Multi-objective trajectory optimization of Space Manoeuvre Vehicle using adaptive differential evolution and modified game theory

Science.gov (United States)

Chai, Runqi; Savvaris, Al; Tsourdos, Antonios; Chai, Senchun

2017-07-01

Highly constrained trajectory optimization for Space Manoeuvre Vehicles (SMV) is a challenging problem. In practice, this problem becomes more difficult when multiple mission requirements are taken into account. Because of the nonlinearity in the dynamic model and even the objectives, it is usually hard for designers to generate a compromised trajectory without violating strict path and box constraints. In this paper, a new multi-objective SMV optimal control model is formulated and parameterized using combined shooting-collocation technique. A modified game theory approach, coupled with an adaptive differential evolution algorithm, is designed in order to generate the pareto front of the multi-objective trajectory optimization problem. In addition, to improve the quality of obtained solutions, a control logic is embedded in the framework of the proposed approach. Several existing multi-objective evolutionary algorithms are studied and compared with the proposed method. Simulation results indicate that without driving the solution out of the feasible region, the proposed method can perform better in terms of convergence ability and convergence speed than its counterparts. Moreover, the quality of the pareto set generated using the proposed method is higher than other multi-objective evolutionary algorithms, which means the newly proposed algorithm is more attractive for solving multi-criteria SMV trajectory planning problem.

Beyond Brainstorming: Exploring Convergence in Teams

DEFF Research Database (Denmark)

Seeber, Isabella; de Vreede, Gert-Jan; Maier, Ronald

2017-01-01

Collaborative brainstorming is often followed by a convergence activity where teams extract the most promising ideas on a useful level of detail from the brainstorming results. Contrary to the wealth of research on electronic brainstorming, there is a dearth of research on convergence. We used...

Convergence analysis of canonical genetic algorithms.

Science.gov (United States)

Rudolph, G

1994-01-01

This paper analyzes the convergence properties of the canonical genetic algorithm (CGA) with mutation, crossover and proportional reproduction applied to static optimization problems. It is proved by means of homogeneous finite Markov chain analysis that a CGA will never converge to the global optimum regardless of the initialization, crossover, operator and objective function. But variants of CGA's that always maintain the best solution in the population, either before or after selection, are shown to converge to the global optimum due to the irreducibility property of the underlying original nonconvergent CGA. These results are discussed with respect to the schema theorem.

convergent methods for calculating thermodynamic Green functions

OpenAIRE

Bowen, S. P.; Williams, C. D.; Mancini, J. D.

1984-01-01

A convergent method of approximating thermodynamic Green functions is outlined briefly. The method constructs a sequence of approximants which converges independently of the strength of the Hamiltonian's coupling constants. Two new concepts associated with the approximants are introduced: the resolving power of the approximation, and conditional creation (annihilation) operators. These ideas are illustrated on an exactly soluble model and a numerical example. A convergent expression for the s...

Log-binomial models: exploring failed convergence.

Science.gov (United States)

Williamson, Tyler; Eliasziw, Misha; Fick, Gordon Hilton

2013-12-13

Relative risk is a summary metric that is commonly used in epidemiological investigations. Increasingly, epidemiologists are using log-binomial models to study the impact of a set of predictor variables on a single binary outcome, as they naturally offer relative risks. However, standard statistical software may report failed convergence when attempting to fit log-binomial models in certain settings. The methods that have been proposed in the literature for dealing with failed convergence use approximate solutions to avoid the issue. This research looks directly at the log-likelihood function for the simplest log-binomial model where failed convergence has been observed, a model with a single linear predictor with three levels. The possible causes of failed convergence are explored and potential solutions are presented for some cases. Among the principal causes is a failure of the fitting algorithm to converge despite the log-likelihood function having a single finite maximum. Despite these limitations, log-binomial models are a viable option for epidemiologists wishing to describe the relationship between a set of predictors and a binary outcome where relative risk is the desired summary measure. Epidemiologists are encouraged to continue to use log-binomial models and advocate for improvements to the fitting algorithms to promote the widespread use of log-binomial models.

Longitudinal follow-up with MR imaging and Gd-DTPA to assess the evolution of multiple sclerosis

International Nuclear Information System (INIS)

Berry, I.; Manelfe, C.; Bensemhoun, C.; Mekies, C.; Clanet, M.

1990-01-01

This paper assesses whether the changes seen on longitudinal follow-up with Gd-DTPA-enhanced MR imaging can help in evaluating the prognosis of multiple sclerosis (MS). Thirty patients with definite MS (relapsing-remitting in 22, progressive-chronic in eight) underwent 54 MR studies performed during disease evolution (21 relapses prior to steroid treatment, eight chronic progressions) and stability (n = 25). Another group of seven patients underwent repetitive MR imaging every 3 months (eight to 10 controls) and also during relapses. MR imaging was performed at 0.5 T with T1- and T2-weighted sequences; Gd-DTPA was injected intravenously (0.1 mmol/kg)

Surface Morphology Evolution Mechanisms of InGaN/GaN Multiple Quantum Wells with Mixture N2/H2-Grown GaN Barrier.

Science.gov (United States)

Zhou, Xiaorun; Lu, Taiping; Zhu, Yadan; Zhao, Guangzhou; Dong, Hailiang; Jia, Zhigang; Yang, Yongzhen; Chen, Yongkang; Xu, Bingshe

2017-12-01

Surface morphology evolution mechanisms of InGaN/GaN multiple quantum wells (MQWs) during GaN barrier growth with different hydrogen (H 2 ) percentages have been systematically studied. Ga surface-diffusion rate, stress relaxation, and H 2 etching effect are found to be the main affecting factors of the surface evolution. As the percentage of H 2 increases from 0 to 6.25%, Ga surface-diffusion rate and the etch effect are gradually enhanced, which is beneficial to obtaining a smooth surface with low pits density. As the H 2 proportion further increases, stress relaxation and H 2 over- etching effect begin to be the dominant factors, which degrade surface quality. Furthermore, the effects of surface evolution on the interface and optical properties of InGaN/GaN MQWs are also profoundly discussed. The comprehensive study on the surface evolution mechanisms herein provides both technical and theoretical support for the fabrication of high-quality InGaN/GaN heterostructures.

A class of convergent neural network dynamics

Science.gov (United States)

Fiedler, Bernold; Gedeon, Tomáš

1998-01-01

We consider a class of systems of differential equations in Rn which exhibits convergent dynamics. We find a Lyapunov function and show that every bounded trajectory converges to the set of equilibria. Our result generalizes the results of Cohen and Grossberg (1983) for convergent neural networks. It replaces the symmetry assumption on the matrix of weights by the assumption on the structure of the connections in the neural network. We prove the convergence result also for a large class of Lotka-Volterra systems. These are naturally defined on the closed positive orthant. We show that there are no heteroclinic cycles on the boundary of the positive orthant for the systems in this class.

Convergent evolution of SWS2 opsin facilitates adaptive radiation of threespine stickleback into different light environments.

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David A Marques

2017-04-01

Full Text Available Repeated adaptation to a new environment often leads to convergent phenotypic changes whose underlying genetic mechanisms are rarely known. Here, we study adaptation of color vision in threespine stickleback during the repeated postglacial colonization of clearwater and blackwater lakes in the Haida Gwaii archipelago. We use whole genomes from 16 clearwater and 12 blackwater populations, and a selection experiment, in which stickleback were transplanted from a blackwater lake into an uninhabited clearwater pond and resampled after 19 y to test for selection on cone opsin genes. Patterns of haplotype homozygosity, genetic diversity, site frequency spectra, and allele-frequency change support a selective sweep centered on the adjacent blue- and red-light sensitive opsins SWS2 and LWS. The haplotype under selection carries seven amino acid changes in SWS2, including two changes known to cause a red-shift in light absorption, and is favored in blackwater lakes but disfavored in the clearwater habitat of the transplant population. Remarkably, the same red-shifting amino acid changes occurred after the duplication of SWS2 198 million years ago, in the ancestor of most spiny-rayed fish. Two distantly related fish species, bluefin killifish and black bream, express these old paralogs divergently in black- and clearwater habitats, while sticklebacks lost one paralog. Our study thus shows that convergent adaptation to the same environment can involve the same genetic changes on very different evolutionary time scales by reevolving lost mutations and reusing them repeatedly from standing genetic variation.

Convergence of knowledge, technology and society beyond convergence of nano-bio-info-cognitive technologies

CERN Document Server

Bainbridge, William; Tonn, Bruce; Whitesides, George

2013-01-01

Convergence of knowledge and technology for the benefit of society (CKTS) is the core opportunity for progress in the 21st century, based on five principles: (1) the interdependence of all components of nature and society, (2) enhancement of creativity and innovation through evolutionary processes of convergence that combine existing principles, and divergence that generates new ones, (3) decision analysis for research and development based on system-logic deduction, (4) higher-level cross-domain languages to generate new solutions and support transfer of new knowledge, and (5) vision-inspired basic research embodied in grand challenges. Solutions are outlined for key societal challenges, including creating new industries and jobs, improving lifelong wellness and human potential, achieving personalized and integrated healthcare and education, and securing a sustainable quality of life for all. This report provides a ten-year “NBIC2” vision within a longer-term framework for converging technology and human...

Explaining convergence of oecd welfare states

DEFF Research Database (Denmark)

Schmitt, C.; Starke, Peter

2011-01-01

of conditional convergence helps to both better describe and explain the phenomenon. By applying error correction models, we examine conditional convergence of various types of social expenditure in 21 OECD countries between 1980 and 2005. Our empirical findings go beyond the existing literature in two respects...

Evolution of resistance to a multiple-herbivore community: genetic correlations, diffuse coevolution, and constraints on the plant's response to selection.

Science.gov (United States)

Wise, Michael J; Rausher, Mark D

2013-06-01

Although plants are generally attacked by a community of several species of herbivores, relatively little is known about the strength of natural selection for resistance in multiple-herbivore communities-particularly how the strength of selection differs among herbivores that feed on different plant organs or how strongly genetic correlations in resistance affect the evolutionary responses of the plant. Here, we report on a field study measuring natural selection for resistance in a diverse community of herbivores of Solanum carolinense. Using linear phenotypic-selection analyses, we found that directional selection acted to increase resistance to seven species. Selection was strongest to increase resistance to fruit feeders, followed by flower feeders, then leaf feeders. Selection favored a decrease in resistance to a stem borer. Bootstrapping analyses showed that the plant population contained significant genetic variation for each of 14 measured resistance traits and significant covariances in one-third of the pairwise combinations of resistance traits. These genetic covariances reduced the plant's overall predicted evolutionary response for resistance against the herbivore community by about 60%. Diffuse (co)evolution was widespread in this community, and the diffuse interactions had an overwhelmingly constraining (rather than facilitative) effect on the plant's evolution of resistance. © 2013 The Author(s). Evolution © 2013 The Society for the Study of Evolution.

RDEL: Restart Differential Evolution algorithm with Local Search Mutation for global numerical optimization

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Ali Wagdy Mohamed

2014-11-01

Full Text Available In this paper, a novel version of Differential Evolution (DE algorithm based on a couple of local search mutation and a restart mechanism for solving global numerical optimization problems over continuous space is presented. The proposed algorithm is named as Restart Differential Evolution algorithm with Local Search Mutation (RDEL. In RDEL, inspired by Particle Swarm Optimization (PSO, a novel local mutation rule based on the position of the best and the worst individuals among the entire population of a particular generation is introduced. The novel local mutation scheme is joined with the basic mutation rule through a linear decreasing function. The proposed local mutation scheme is proven to enhance local search tendency of the basic DE and speed up the convergence. Furthermore, a restart mechanism based on random mutation scheme and a modified Breeder Genetic Algorithm (BGA mutation scheme is combined to avoid stagnation and/or premature convergence. Additionally, an exponent increased crossover probability rule and a uniform scaling factors of DE are introduced to promote the diversity of the population and to improve the search process, respectively. The performance of RDEL is investigated and compared with basic differential evolution, and state-of-the-art parameter adaptive differential evolution variants. It is discovered that the proposed modifications significantly improve the performance of DE in terms of quality of solution, efficiency and robustness.

Convergence Performance of Adaptive Algorithms of L-Filters

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Robert Hudec

2003-01-01

Full Text Available This paper deals with convergence parameters determination of adaptive algorithms, which are used in adaptive L-filters design. Firstly the stability of adaptation process, convergence rate or adaptation time, and behaviour of convergence curve belong among basic properties of adaptive algorithms. L-filters with variety of adaptive algorithms were used to their determination. Convergence performances finding of adaptive filters is important mainly for their hardware applications, where filtration in real time or adaptation of coefficient filter with low capacity of input data are required.

Convergence analysis of directed signed networks via an M-matrix approach

Science.gov (United States)

Meng, Deyuan

2018-04-01

This paper aims at solving convergence problems on directed signed networks with multiple nodes, where interactions among nodes are described by signed digraphs. The convergence analysis is achieved by matrix-theoretic and graph-theoretic tools, in which M-matrices play a central role. The fundamental digon sign-symmetry assumption upon signed digraphs can be removed with the proposed analysis approach. Furthermore, necessary and sufficient conditions are established for semi-positive and positive stabilities of Laplacian matrices of signed digraphs, respectively. A benefit of this result is that given strong connectivity, a directed signed network can achieve bipartite consensus (or state stability) if and only if the signed digraph associated with it is structurally balanced (or unbalanced). If the interactions between nodes are described by a signed digraph only with spanning trees, a directed signed network can achieve interval bipartite consensus (or state stability) if and only if the signed digraph contains a structurally balanced (or unbalanced) rooted subgraph. Simulations are given to illustrate the developed results by considering signed networks associated with digon sign-unsymmetric signed digraphs.

Adaptive Suspicious Prevention for Defending DoS Attacks in SDN-Based Convergent Networks.

Science.gov (United States)

Dao, Nhu-Ngoc; Kim, Joongheon; Park, Minho; Cho, Sungrae

2016-01-01

The convergent communication network will play an important role as a single platform to unify heterogeneous networks and integrate emerging technologies and existing legacy networks. Although there have been proposed many feasible solutions, they could not become convergent frameworks since they mainly focused on converting functions between various protocols and interfaces in edge networks, and handling functions for multiple services in core networks, e.g., the Multi-protocol Label Switching (MPLS) technique. Software-defined networking (SDN), on the other hand, is expected to be the ideal future for the convergent network since it can provide a controllable, dynamic, and cost-effective network. However, SDN has an original structural vulnerability behind a lot of advantages, which is the centralized control plane. As the brains of the network, a controller manages the whole network, which is attractive to attackers. In this context, we proposes a novel solution called adaptive suspicious prevention (ASP) mechanism to protect the controller from the Denial of Service (DoS) attacks that could incapacitate an SDN. The ASP is integrated with OpenFlow protocol to detect and prevent DoS attacks effectively. Our comprehensive experimental results show that the ASP enhances the resilience of an SDN network against DoS attacks by up to 38%.

Neutron gain for converging guide tubes

International Nuclear Information System (INIS)

Mildner, D.F.R.

1982-01-01

The method of acceptance diagrams is used to obtain analytical expressions for the neutron gain of a one-dimensional converging guide tube. It is found that the results are more easily expressed by analyzing the acceptance diagram at the exit of the funnel. The results are compared with those for the straight guide. When both guides have the same dimensions at the guide exit, the converging guide has higher transmitted intensity but with greater divergence of the beam. This analytical method is useful to assess the performance of a converging guide, though numerical computations may be required for detailed analysis of a guide system. (orig.)

Convergence

DEFF Research Database (Denmark)

Prasad, Ramjee

2009-01-01

This paper presents the main conclusions which can be drawn from the discussions on Future Communication Systems and lessons on Unpredictable Future of Wireless Communication Systems. Future systems beyond the third generation are already under discussions in international bodies, such as ITU, WW...... and R&D programmes worldwide. The incoming era is characterized by the convergence of networks and access technology and the divergence of applications. Future mobile communication systems should bring something more than only faster data or wireless internet access....

Convergence in energy consumption per capita among ASEAN countries

International Nuclear Information System (INIS)

Mishra, Vinod; Smyth, Russell

2014-01-01

We test for convergence in energy consumption per capita among ASEAN countries over the period 1971 to 2011 using the panel KPSS stationarity test and panel Lagrange multiplier (LM) unit root test. The results for the panel stationarity and unit root tests with structural breaks find support for energy convergence in ASEAN. - Highlights: • We test for convergence in energy consumption per capita among the ASEAN nations. • Univariate conventional unit root tests provide mixed evidence of convergence. • Panel unit root tests with structural breaks support convergence hypothesis

Automatic fission source convergence criteria for Monte Carlo criticality calculations

International Nuclear Information System (INIS)

Shim, Hyung Jin; Kim, Chang Hyo

2005-01-01

The Monte Carlo criticality calculations for the multiplication factor and the power distribution in a nuclear system require knowledge of stationary or fundamental-mode fission source distribution (FSD) in the system. Because it is a priori unknown, so-called inactive cycle Monte Carlo (MC) runs are performed to determine it. The inactive cycle MC runs should be continued until the FSD converges to the stationary FSD. Obviously, if one stops them prematurely, the MC calculation results may have biases because the followup active cycles may be run with the non-stationary FSD. Conversely, if one performs the inactive cycle MC runs more than necessary, one is apt to waste computing time because inactive cycle MC runs are used to elicit the fundamental-mode FSD only. In the absence of suitable criteria for terminating the inactive cycle MC runs, one cannot but rely on empiricism in deciding how many inactive cycles one should conduct for a given problem. Depending on the problem, this may introduce biases into Monte Carlo estimates of the parameters one tries to calculate. The purpose of this paper is to present new fission source convergence criteria designed for the automatic termination of inactive cycle MC runs

Local multiplicative Schwarz algorithms for convection-diffusion equations

Science.gov (United States)

Cai, Xiao-Chuan; Sarkis, Marcus

1995-01-01

We develop a new class of overlapping Schwarz type algorithms for solving scalar convection-diffusion equations discretized by finite element or finite difference methods. The preconditioners consist of two components, namely, the usual two-level additive Schwarz preconditioner and the sum of some quadratic terms constructed by using products of ordered neighboring subdomain preconditioners. The ordering of the subdomain preconditioners is determined by considering the direction of the flow. We prove that the algorithms are optimal in the sense that the convergence rates are independent of the mesh size, as well as the number of subdomains. We show by numerical examples that the new algorithms are less sensitive to the direction of the flow than either the classical multiplicative Schwarz algorithms, and converge faster than the additive Schwarz algorithms. Thus, the new algorithms are more suitable for fluid flow applications than the classical additive or multiplicative Schwarz algorithms.

Convergence testing for MCNP5 Monte Carlo eigenvalue calculations

International Nuclear Information System (INIS)

Brown, F.; Nease, B.; Cheatham, J.

2007-01-01

Determining convergence of Monte Carlo criticality problems is complicated by the statistical noise inherent in the random, walks of the neutrons in each generation. The latest version of MCNP5 incorporates an important new tool for assessing convergence: the Shannon entropy of the fission source distribution, H src . Shannon entropy is a well-known concept from information theory and provides a single number for each iteration to help characterize convergence trends for the fission source distribution. MCNP5 computes H src for each iteration, and these values may be plotted to examine convergence trends. Convergence testing should include both k eff and H src , since the fission distribution will converge more slowly than k eff , especially when the dominance ratio is close to 1.0. (authors)

Optimal solutions for a bio mathematical model for the evolution of smoking habit

Science.gov (United States)

Sikander, Waseem; Khan, Umar; Ahmed, Naveed; Mohyud-Din, Syed Tauseef

In this study, we apply Variation of Parameter Method (VPM) coupled with an auxiliary parameter to obtain the approximate solutions for the epidemic model for the evolution of smoking habit in a constant population. Convergence of the developed algorithm, namely VPM with an auxiliary parameter is studied. Furthermore, a simple way is considered for obtaining an optimal value of auxiliary parameter via minimizing the total residual error over the domain of problem. Comparison of the obtained results with standard VPM shows that an auxiliary parameter is very feasible and reliable in controlling the convergence of approximate solutions.

A convergent reformulation of perturbative QCD

International Nuclear Information System (INIS)

Alves, R.J.G.

2000-10-01

We present and explore a new formulation of perturbative QCD based not on the renormalised coupling but on the dimensional transmutation parameter of the theory and the property of asymptotic scaling. The approach yields a continued function, the iterated function being that involved in the solution of the two-loop β-function equation. In the so-called large-b limit the continued function reduces to a continued fraction and the successive approximants are diagonal Pade approximants. We investigate numerically the convergence of successive approximants using the leading-b approximation, motivated by renormalons, to model the all-orders result. We consider the Adler D-function of vacuum polarisation, the Polarised Bjorken and Gross-LIewellyn Smith sum rules, the (unpolarised) Bjorken sum rule, and the Minkowskian quantities R τ and the R-ratio of e + e - annihilation. In contrast to diagonal Pade approximants the truncated continued function method gives remarkably stable large-order approximants in cases where infrared renormalon effects are important. We also use the new approach to determine the QCD fundamental parameters from the R τ and the R-ratio measurements, where we find Λ-tilde (3)/MS = 516 ± 48 MeV (which yields α s (μ = m τ ) = 0.360 -0.020 +0.021 ), and Λ-tilde (5)/MS = 299 -7 +6 MeV (which yields α s (μ = m z 0 ) = 0.1218 ± 0.0004), respectively. The evolution of the former value to the m z 0 energy results in α s (μ = m z 0 ) = 0.123 ± 0.002. These values are in line with other determinations available in the literature. We implement the Complete Renormalisation Group Improvement (CORGI) scheme throughout all the calculations. We report on how the mathematical concept of Stieltjes series can be used to assess the convergence of Pade approximants of perturbative series. We find that the combinations of UV renormalons which occur in perturbative QCD may or may not be Stieltjes series depending on the renormalisation scheme used. (author)

Digital Convergence and Content Regulation

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Michael John Starks

2014-12-01

Full Text Available Broadcasting, Press and Internet journalism systems of distribution are converging: the same infrastructure can deliver all three historically separate services. Reception devices mirror this: the Connected TV, the tablet and the smart phone overlap in their functionality. Service overlaps are evident too, with broadcasters providing online and on-demand services and newspapers developing electronic versions. Does this mean that media regulation policies must converge too?My argument is that they should, though only where historically different communications are now fulfilling a similar function, e.g. broadcaster online services and electronic versions of newspapers. Convergence requires a degree of harmonisation and, to this end, I advocate a review of UK broadcasting's 'due impartiality' requirement and of the UK's application of the public service concept. I also argue for independent self-regulation (rather than state-based regulation of non-public-service broadcasting journalism.

Rates of convergence of Brezier net over triangles

International Nuclear Information System (INIS)

Feng Yuyu.

1986-12-01

It is well known (Farin, 1979) that the sequence of Bezier nets f-circumflex n (x) associated with Bernstein-Bezier surface over a triangle converges to the surface uniformly as n goes to infinity. In this paper the precise rates of convergence are given. The pointwise convergence result and saturation theorem are presented. (author). 7 refs

Specialisation and Convergence in European Regions

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Enrico Marelli

2007-09-01

Full Text Available The purpose of this paper was to analyze specialization and convergence of European countries and regions, within the framework of integration in the EU. This is important not only for long-term real convergence processes, but also for a proper functioning of the monetary union (in the line of research on the OCA's criteria, asymmetry of shocks and synchronization of business cycles. The position of new member states is particularly delicate, also considering the forthcoming adoption of the euro by some of them. As indicated by the EU Treaty, economic growth should be balanced with economic and social cohesion that includes a careful consideration of regional disparities. Our empirical investigation focuses on the regions of EU25, further broken up into other relevant groupings (EU15, EMU, and the new members' EU10 group, over the period from 1980 (or 1990 for EU10 to 2005. This paper considers a rather fine regional disaggregation (NUTS-2 level, counting 250 regions. The analysis of different indices of specialisation point to a prevalent increase of homogeneity of sector structures across European regions, although in some cases (especially in the industrial sector and in some services specialisation has increased. For convergence, a sigma convergence's analysis confirms a reduction of disparities, both at a country and regional level. However, a trade-off between fast national growth and internal distribution has emerged in the early stages of development, as in the case of new members. Moreover, beta convergence has also been established - regarding per capita income, employment and productivity - for almost all territorial aggregates (excluding the new members since 1999. The addition of structural variables, following a beta-conditional approach, indicates a positive role for services and a negative impact of agriculture. Finally, some preliminary results have been obtained by the innovative inclusion of specialisation indices within

IPv6 Convergence for IoT Cyber–Physical Systems

Directory of Open Access Journals (Sweden)

Keith Nolan

2018-03-01

Full Text Available We describe the evolution of the IoT towards a heterogeneous multitopology network subject to dynamic change and volatility yet still capable of secure and dependable operation. As part of this evolution, we outline the key changes in wireless communications technologies and heterogeneous networking that have arisen during the development of the IoT. We briefly outline the emerging area of cyber–physical systems, and associated technical challenges. We then describe how IP convergence can be viewed as the narrow waist connecting endpoint devices and fieldbus devices with applications and services in new Industry 4.0, and cyber–physical system use cases. We outline how a protocol-packing approach can be used for encapsulating LoRaWAN frames with IEEE 802.15.4 and IEEE 802.11 frames. Extending this, we propose a method for ultracompressed IPv6 signaling, and detail how this can be achieved in an example low-power wide-area technology, namely LoRaWAN. To support our proposed approach, we provide real-world analyses where IPv6 commands undergo a process of ultracompression and are then conveyed to a LoRaWAN endpoint. We find that IPv6 command ultracompression can potentially support command packet sizes that are over 20x smaller than the reported worst-case maximum protocol data unit size of 81 bytes.

ACCOUNTING STANDARD SETTING IN THE INTERNATIONAL ARENA: UPDATE ON THE CONVERGENCE PROJECT

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Bonaci Carmen Giorgiana

2012-07-01

Full Text Available Our paper contributes to the literature on international accounting by focusing on the standard setting process. As documented by research literature, accounting regulation can enhance corporate governance (Melis and Carta, 2010, corporate reporting being expected to reduce information asymmetry. Based on accounting research and trade literature we first synthesize recent evolutions in the international accounting arena. We therefore position our study within current realities significantly marked by uncertainty in relation to the world wide globalization process. The objective of our paper is to perform an analysis that would help assess further developments of the convergence project. This is done by looking at the current status of the projects being developed under the IASB –FASB collaboration, as well as by developing a comparison between IFRS and US GAAP. The employed research methodology relies on analyzing data provided through the IASB and the FASB’s websites, as well as other official documents being issued by the two Boards. The assessment of the projects was done by reviewing exposure documents and monitoring the Boards’ deliberations, while the developed comparison requires accounting regulations content analysis. Concluding upon the Boards’ ongoing projects, we might identify areas in which convergence seems to be quite close (such as revenue recognition and leasing, but also areas in which convergence becomes even more challenging (such as financial instruments or the particular case of offsetting. Similar to other studies being developed within accounting research and trade literature (SEC 2011: 8 we may conclude that, generally, US GAAP present more detailed, specific requirements than IFRS.

Evolution and adaptation of Pseudomonas aeruginosa in cystic fibrosis airways

DEFF Research Database (Denmark)

Madsen Sommer, Lea Mette

of natural environments, the primary obstacle is re-sampling of the samepopulation over time, especially if the population is small.Nevertheless, it has been accomplished: Chronic airway infections of cystic fibrosis (CF) patients have offered a unique view into the adaptationand evolution of Pseudomonas...... to the CF airways. From this analysis we found common clonal lineages among the patients, evidence of patient-to-patient transmission, historic contingencies, and convergent evolution of 52 candidate pathoadaptive genes. By further genome sequencing 26 P. aeruginosa isolates from four Italian CF patients...

Revisiting convergence: A research note.

Science.gov (United States)

Clark, Rob

2015-09-01

A number of recent studies show that income inequality is declining between countries. In this research note, I question the significance of this trend by examining the role of initial conditions in producing convergence. An important (but neglected) property of inequality dynamics is the tendency for extreme distributions to become more moderate. When income disparities are large, the subsequent trend is biased toward convergence. Conversely, when initial conditions approach parity, divergence becomes the more likely long-term outcome. I apply this principle to trends in GDP PC across 127 countries during the 1980-2010 period. Using counterfactual analysis, I manipulate the initial level of inequality in GDP PC while holding constant each country's observed growth rate during the sample period. I find that the growth dynamics of GDP PC produce either convergence or divergence based simply on the initial distribution of income. The point of transition occurs at a moderate level of inequality, whether using population weights (Gini=.365) or not (Gini=.377). I conclude that the recent convergence observed in GDP PC is primarily a function of large income gaps between countries and would not have materialized at more moderate levels of initial inequality. By contrast, an examination of the pre-1950 period reveals divergent growth patterns that are not sensitive to initial conditions. Copyright © 2015 Elsevier Inc. All rights reserved.

CONVERGENCE OF TECHNOLOGIES

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R. Siriram

2012-01-01

Full Text Available

ENGLISH ABSTRACT: Technology is a catalyst for competitive advantage. However, it is how technology is used that leads to a firm’s improved performance. In this article, an investigative framework is constructed to understand better what strategically drives new technology adoption. The strategic drivers include technology and business strategy alignment, better technology planning and selection of new technologies, the effects on a firm’s culture and climate, links to a firm’s organisational and environmental evolution, and benefits through convergence and collaboration. Using an investigative framework, it is shown how the strategic drivers link to improve a firm’s performance, producing competitive advantage. The investigative framework is tested using structural equation modelling. Various hypotheses are formed, and recommendations for further research are made.

AFRIKAANSE OPSOMMING: Tegnologie is ‘n katalisator vir mededingende voordeel. Dit is egter hoe tegnologie aangewend word wat aanleiding gee tot ‘n onderneming se verbeterde prestasie. In hierdie artikel word ‘n ondersoekende raamwerk gekonstrueer om insig te kry in dit wat die aanvaarding van nuwe tegnologie strategies dryf. Die strategiese dryfvere sluit in die belyning van tegnologie en ondernemingstrategie, beter tegnologiebeplanning en seleksie van nuwe tegnologieë, die effek op ‘n onderneming se kultuur en klimaat, koppeling na ‘n onderneming se organisatoriese en omgewingsevolusie, en voordele verkry deur konvergensie en samewerking. Deur ‘n ondersoekende raamwerk te gebruik, word daar getoon dat die strategiese dryfvere koppel om ‘n onderneming se prestasie te verbeter en sodoende ‘n mededingende voordeel te skep. Die raamwerk word getoets en hipoteses geformuleer waarna aanbevelings oor verdere navorsing aan die hand gedoen word.

Gender, race, and class: intersecting oppressions and convergences reproducing inequalities

Directory of Open Access Journals (Sweden)

Flávia Biroli

2015-12-01

Full Text Available The article analyses approaches to the convergences between gender, class and race within theoretical debates in the last decades, focusing especially on feminism. It aims to present a broad and non-homogeneous field of researches, that has as a common ground the understanding that oppressions are multiple and complex and it is not possible to understand social inequalities when one variable is taken separately. The relative prominence of each axe, its meaning and the comprehension of the way they operate together vary in the three different sets of approaches discussed in the article: marxist or socialist feminism, black feminism, and the studies of intersectionalities

Influence of Kuroshio SST front in the East China Sea on the climatological evolution of Meiyu rainband

Science.gov (United States)

Xu, Mimi; Xu, Haiming; Ren, Huijun

2018-02-01

The influence of Kuroshio sea surface temperature (SST) front in the East China Sea (ECS) on the temporal evolution of climatological Meiyu rainband was investigated using a suite of high-resolution satellite observations and a reanalysis dataset from 2000 to 2011. During the northward seasonal march of Meiyu rainband from the warmer flank of the SST front to the colder flank, the climatological rainband strength weakened substantially despite large-scale environment became more conducive to intensify precipitation. A sharp reduction in occurrence frequency of precipitation with relatively shallower depth and smaller intensity was responsible for the weakening of Meiyu rainband. During the northward migration of Meiyu rainband, individual precipitation events became deeper and more intensive, and the contribution of convective precipitation to the rainband was enhanced, associated with the seasonal northward extension of high convective instability region over the ECS. The characteristics of Meiyu rainband evolution were generally supported by cloud observations. When Meiyu rainband was located on the warmer flank of the SST front, local enhanced mean surface wind convergence and variance of convergence at synoptic timescale by the warm SST of the Kuroshio favored strong surface convergence that may trigger precipitation. A detailed moisture budget analysis revealed that the major part of moisture for Meiyu precipitation was supplied by low-level wind convergence, with much smaller contribution from moisture advection. The variation of climatological precipitation associated with Meiyu northward migration depended on SST modulation of both surface evaporation and low-level moisture convergence over the ECS.

Is the environmental performance of industrialized countries converging? A 'SURE' approach to testing for convergence

International Nuclear Information System (INIS)

Camarero, Mariam; Picazo-Tadeo, Andres J.; Tamarit, Cecilio

2008-01-01

In this paper, we test for convergence in the environmental performance of a sample of OECD countries, with data ranging from 1971 to 2002. First, we use Data Envelopment Analysis (DEA) to compute two environmental performance indicators (EPIs) in the production theory framework. Second, we propose the use of a sequential multivariate approach to test for convergence in environmental performance. These tests allow us to reconcile the time series literature with the cross-sectional dimension, which is basic when testing for convergence in regional blocs. The SURE technique is used, which allows for the existence of correlations across the series without imposing a common speed of mean reversion. The empirical results show that the group of countries as a whole, as well as the majority of countries considered on an individual basis (results for some countries vary between EPIs), are catching-up with Switzerland (the benchmark country). (author)

Reduced vergence adaptation is associated with a prolonged output of convergence accommodation in convergence insufficiency.

Science.gov (United States)

Sreenivasan, Vidhyapriya; Bobier, William R

2014-07-01

Convergence insufficiency (CI) is a developmental visual anomaly defined clinically by a reduced near point of convergence, a reduced capacity to view through base-out prisms (fusional convergence); coupled with asthenopic symptoms typically blur and diplopia. Experimental studies show reduced vergence parameters and tonic adaptation. Based upon current models of accommodation and vergence, we hypothesize that the reduced vergence adaptation in CI leads to excessive amounts of convergence accommodation (CA). Eleven CI participants (mean age=17.4±2.3 years) were recruited with reduced capacity to view through increasing magnitudes of base out (BO) prisms (mean fusional convergence at 40 cm=12±0.9Δ). Testing followed our previous experimental design for (n=11) binocularly normal adults. Binocular fixation of a difference of Gaussian (DoG) target (0.2 cpd) elicited CA responses during vergence adaptation to a 12Δ BO. Vergence and CA responses were obtained at 3 min intervals over a 15 min period and time course were quantified using exponential decay functions. Results were compared to previously published data on eleven binocular normals. Eight participants completed the study. CI's showed significantly reduced magnitude of vergence adaptation (CI: 2.9Δ vs. normals: 6.6Δ; p=0.01) and CA reduction (CI=0.21 D, Normals=0.55 D; p=0.03). However, the decay time constants for adaptation and CA responses were not significantly different. CA changes were not confounded by changes in tonic accommodation (Change in TA=0.01±0.2D; p=0.8). The reduced magnitude of vergence adaptation found in CI patients resulting in higher levels of CA may potentially explain their clinical findings of reduced positive fusional vergence (PFV) and the common symptom of blur. Copyright © 2014 Elsevier B.V. All rights reserved.

Convergent and divergent validity of the Mullen Scales of Early Learning in young children with and without autism spectrum disorder.

Science.gov (United States)

Swineford, Lauren B; Guthrie, Whitney; Thurm, Audrey

2015-12-01

The purpose of this study was to report on the construct, convergent, and divergent validity of the Mullen Scales of Early Learning (MSEL), a widely used test of development for young children. The sample consisted of 399 children with a mean age of 3.38 years (SD = 1.14) divided into a group of children with autism spectrum disorder (ASD) and a group of children not on the autism spectrum, with and without developmental delays. The study used the MSEL and several other measures assessing constructs relevant to the age range--including developmental skills, autism symptoms, and psychopathology symptoms--across multiple methods of assessment. Multiple-group confirmatory factor analyses revealed good overall fit and equal form of the MSEL 1-factor model across the ASD and nonspectrum groups, supporting the construct validity of the MSEL. However, neither full nor partial invariance of factor loadings was established because of the lower loadings in the ASD group compared with the nonspectrum group. Exploratory structural equation modeling revealed that other measures of developmental skills loaded together with the MSEL domain scores on a Developmental Functioning factor, supporting convergent validity of the MSEL. Divergent validity was supported by the lack of loading of MSEL domain scores on Autism Symptoms or Emotion/Behavior Problems factors. Although factor structure and loadings varied across groups, convergent and divergent validity findings were similar in the ASD and nonspectrum samples. Together, these results demonstrate evidence for the construct, convergent, and divergent validity of the MSEL using powerful data-analytic techniques. (c) 2015 APA, all rights reserved).

Post-convergence automatic differentiation of iterative schemes

International Nuclear Information System (INIS)

Azmy, Y.Y.

1997-01-01

A new approach for performing automatic differentiation (AD) of computer codes that embody an iterative procedure, based on differentiating a single additional iteration upon achieving convergence, is described and implemented. This post-convergence automatic differentiation (PAD) technique results in better accuracy of the computed derivatives, as it eliminates part of the derivatives convergence error, and a large reduction in execution time, especially when many iterations are required to achieve convergence. In addition, it provides a way to compute derivatives of the converged solution without having to repeat the entire iterative process every time new parameters are considered. These advantages are demonstrated and the PAD technique is validated via a set of three linear and nonlinear codes used to solve neutron transport and fluid flow problems. The PAD technique reduces the execution time over direct AD by a factor of up to 30 and improves the accuracy of the derivatives by up to two orders of magnitude. The PAD technique's biggest disadvantage lies in the necessity to compute the iterative map's Jacobian, which for large problems can be prohibitive. Methods are discussed to alleviate this difficulty

Fast converging minimum probability of error neural network receivers for DS-CDMA communications.

Science.gov (United States)

Matyjas, John D; Psaromiligkos, Ioannis N; Batalama, Stella N; Medley, Michael J

2004-03-01

We consider a multilayer perceptron neural network (NN) receiver architecture for the recovery of the information bits of a direct-sequence code-division-multiple-access (DS-CDMA) user. We develop a fast converging adaptive training algorithm that minimizes the bit-error rate (BER) at the output of the receiver. The adaptive algorithm has three key features: i) it incorporates the BER, i.e., the ultimate performance evaluation measure, directly into the learning process, ii) it utilizes constraints that are derived from the properties of the optimum single-user decision boundary for additive white Gaussian noise (AWGN) multiple-access channels, and iii) it embeds importance sampling (IS) principles directly into the receiver optimization process. Simulation studies illustrate the BER performance of the proposed scheme.

Well-Tempered Metadynamics Converges Asymptotically

Science.gov (United States)

Dama, James F.; Parrinello, Michele; Voth, Gregory A.

2014-06-01

Metadynamics is a versatile and capable enhanced sampling method for the computational study of soft matter materials and biomolecular systems. However, over a decade of application and several attempts to give this adaptive umbrella sampling method a firm theoretical grounding prove that a rigorous convergence analysis is elusive. This Letter describes such an analysis, demonstrating that well-tempered metadynamics converges to the final state it was designed to reach and, therefore, that the simple formulas currently used to interpret the final converged state of tempered metadynamics are correct and exact. The results do not rely on any assumption that the collective variable dynamics are effectively Brownian or any idealizations of the hill deposition function; instead, they suggest new, more permissive criteria for the method to be well behaved. The results apply to tempered metadynamics with or without adaptive Gaussians or boundary corrections and whether the bias is stored approximately on a grid or exactly.

Long term fault system reorganization of convergent and strike-slip systems

Science.gov (United States)

Cooke, M. L.; McBeck, J.; Hatem, A. E.; Toeneboehn, K.; Beyer, J. L.

2017-12-01

Laboratory and numerical experiments representing deformation over many earthquake cycles demonstrate that fault evolution includes episodes of fault reorganization that optimize work on the fault system. Consequently, the mechanical and kinematic efficiencies of fault systems do not increase monotonically through their evolution. New fault configurations can optimize the external work required to accommodate deformation, suggesting that changes in system efficiency can drive fault reorganization. Laboratory evidence and numerical results show that fault reorganization within accretion, strike-slip and oblique convergent systems is associated with increasing efficiency due to increased fault slip (frictional work and seismic energy) and commensurate decreased off-fault deformation (internal work and work against gravity). Between episodes of fault reorganization, fault systems may become less efficient as they produce increasing off fault deformation. For example, laboratory and numerical experiments show that the interference and interaction between different fault segments may increase local internal work or that increasing convergence can increase work against gravity produced by a fault system. This accumulation of work triggers fault reorganization as stored work provides the energy required to grow new faults that reorganize the system to a more efficient configuration. The results of laboratory and numerical experiments reveal that we should expect crustal fault systems to reorganize following periods of increasing inefficiency, even in the absence of changes to the tectonic regime. In other words, fault reorganization doesn't require a change in tectonic loading. The time frame of fault reorganization depends on fault system configuration, strain rate and processes that relax stresses within the crust. For example, stress relaxation may keep pace with stress accumulation, which would limit the increase in the internal work and gravitational work so that

Semi-convergence properties of Kaczmarz’s method

DEFF Research Database (Denmark)

Elfving, Tommy; Hansen, Per Christian; Nikazad, Touraj

2014-01-01

Kaczmarz’s method—sometimes referred to as the algebraic reconstruction technique—is an iterative method that is widely used in tomographic imaging due to its favorable semi-convergence properties. Specifically, when applied to a problem with noisy data, during the early iterations it converges......-convergence of Kaczmarz’s method as well as its projected counterpart (and their block versions). To do this we study how the data errors propagate into the iteration vectors and we derive upper bounds for this noise propagation. Our bounds are compared with numerical results obtained from tomographic imaging....

DRIVERS OF LONG-TERM CONVERGENCE. FOCUS ON ROMANIA

Directory of Open Access Journals (Sweden)

MANUELA UNGURU

2014-11-01

Full Text Available With initial low levels of income per capita, a declining population and relatively modest economic growth rates, there are little prospects of diminishing the gap between Romania and the EU countries. Nevertheless, in the long term, convergence is expected. The question then arises, “What are the drivers and their likely potential to boost economic growth and the catching-up process?”. This paper presents shortly the theoretical background of economic convergence and then focuses on the assessment of possible paths of Romania’s convergence towards the EU. Based on the existing long-term macroeconomic projections and the assessment of the possible future developments of the drivers of economic growth, we have built three scenarios of economic convergence, highlighting the possible timespan of convergence. We have employed growth accounting methods to decompose output growth rate into production factors’ contributions (capital and labour and total factor productivity.

Investigation of Surface Phenomena in Shocked Tin in Converging Geometry

Energy Technology Data Exchange (ETDEWEB)

Rousculp, Christopher L. [Los Alamos National Laboratory; Oro, David Michael [Los Alamos National Laboratory; Griego, Jeffrey Randall [Los Alamos National Laboratory; Turchi, Peter John [Los Alamos National Laboratory; Reinovsky, Robert Emil [Los Alamos National Laboratory; Bradley, Joseph Thomas [Los Alamos National Laboratory; Cheng, Baolian [Los Alamos National Laboratory; Freeman, Matthew Stouten [Los Alamos National Laboratory; Patten, Austin Randall [Los Alamos National Laboratory

2016-03-21

There is great interest in the behavior of the free surface of tin under shock loading. While it is known that meso-scale surface imperfections can seed the Richtmyer- Meshkov Instability (RMI) for a surface that is melted on release, much less is known about a tin surface that is solid, but plastically deforming. Here material properties such as shear and yield strength come into play especially in converging geometry. Previous experiments have been driven by direct contact HE. Usually a thin, flat target coupon is fielded with various single-mode, sinusoidal, machined, profiles on the free surface. The free surface is adjacent to either vacuum or an inert receiver gas. Most of these previous driver/target configurations have been nominal planer geometry. With modern HE it has been straightforward to shock tin into melt on release. However it has been challenging to achieve a low enough pressure for solid state on release. Here we propose to extend the existing base of knowledge to include the behavior of the free surface of tin in cylindrical converging geometry. By shock loading a cylindrical tin shell with a magnetically driven cylindrical liner impactor, the free surface evolution can be diagnosed with proton radiography. With the PHELIX capacitor bank, the drive can easily be varied to span the pressure range to achieve solid, mixed, and liquid states on release. A conceptual cylindrical liner and target is shown in Figure 1.

Plasma-induced evolution behavior of space-charge-limited current for multiple-needle cathodes

International Nuclear Information System (INIS)

Li Limin; Liu Lie; Zhang Jun; Wen Jianchun; Liu Yonggui; Wan Hong

2009-01-01

Properties of the plasma and beam flow produced by tufted carbon fiber cathodes in a diode powered by a ∼500 kV, ∼400 ns pulse are investigated. Under electric fields of 230-260 kV cm -1 , the electron current density was in the range 210-280 A cm -2 , and particularly at the diode gap of 20 mm, a maximum beam power density of about 120 MW cm -2 was obtained. It was found that space-charge-limited current exhibited an evolution behavior as the accelerating pulse proceeded. There exists a direct relation between the movement of plasma within the diode and the evolution of space-charge-limited current. Initially in the accelerating pulse, the application of strong electric fields caused the emission sites to explode, forming cathode flares or plasma spots, and in this stage the space-charge-limited current was approximately described by a multiple-needle cathode model. As the pulse proceeded, these plasma spots merged and expanded towards the anode, thus increasing the emission area and shortening the diode gap, and the corresponding space-charge-limited current followed a planar cathode model. Finally, the space-charge-limited current is developed from a unipolar flow into a bipolar flow as a result of the appearance of anode plasma. In spite of the nonuniform distribution of cathode plasma, the cross-sectional uniformity of the extracted electron beam is satisfactory. The plasma expansion within the diode is found to be a major factor in the diode perveance growth and instability. These results show that these types of cathodes can offer promising applications for high-power microwave tubes.

Frequency response functions for nonlinear convergent systems

NARCIS (Netherlands)

Pavlov, A.V.; Wouw, van de N.; Nijmeijer, H.

2007-01-01

Convergent systems constitute a practically important class of nonlinear systems that extends the class of asymptotically stable linear time-invariant systems. In this note, we extend frequency response functions defined for linear systems to nonlinear convergent systems. Such nonlinear frequency

The historical evolution of thought regarding multiple micronutrient nutrition.

Science.gov (United States)

Semba, Richard D

2012-01-01

Multiple micronutrient nutrition is an idea that originated in the 1940s and exemplifies the iterative nutritional paradigm. In the first four decades of the 20th century, scientists sought to separate and characterize the vitamins that were responsible for xerophthalmia, rickets, pellagra, scurvy, and beriberi. The dietary requirements of the different micronutrients began to be established in the early 1940s. Surveys showed that multiple micronutrient deficiencies were widespread in industrialized countries, and the problem was addressed by use of cod-liver oil, iodized salt, fortified margarine, and flour fortification with multiple micronutrients, and, with rising living standards, the increased availability and consumption of animal source foods. After World War II, surveys showed that multiple micronutrient deficiencies were widespread in developing countries. Approaches to the elimination of multiple micronutrient deficiencies include periodic vitamin A supplementation, iodized salt, targeted iron/folate supplementation, fortified flour, other fortified foods, home fortification with micronutrient powders, and homestead food production. The prevention of multiple micronutrient malnutrition is a key factor in achieving the Millennium Development Goals, given the important effects of micronutrients on health and survival.

Trade-Off or Convergence? The Role of Food Security in the Evolution of Food Discourse in Italy

Science.gov (United States)

Brunori, Gianluca; Malandrin, Vanessa; Rossi, Adanella

2013-01-01

In this paper we analyse the role that "food security" has played in the evolution of the food discourse in Italy, a country with a strong and internationally recognized food culture. We identify three phases of this evolution: in the first phase, from the end of the Second World War to the end of the 1980s, the "modernization"…

Converged Registries Solution (CRS)

Data.gov (United States)

Department of Veterans Affairs — The Converged Registries platform is a hardware and software architecture designed to host individual patient registries and eliminate duplicative development effort...

On convergence of nuclear and correlation operators in Hilbert space