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Sample records for multi-slice ct application

  1. The clinical application of multi-slice spiral CT angiography in abdominal aortic disease

    Institute of Scientific and Technical Information of China (English)

    2005-01-01

    Objective: To evaluate the clinical application of multi-slice spiral CT angiography(MSCTA) in the assessment of abdominal aortic disease. Methods: Fifty-four patients underwent multi-slice spiral CT angiography of abdomen. Contrast agent (Omnipaque 300 I g/L) 1.5 ml/kg was injected and the injection rate was 3 ml/s. The delay time was determined by bolus tracking technique,Tll level abdominal aorta was set as the target vessel and the threshold was 180-200 Hu, slice width was 3 mm and with a pitch of 4-6.Original data were transferred to working-station to perform functional reconstruction. Results: Ten cases were normal, twenty-eight cases were abdominal aortic aneurysms, five abdominal aortic dissecting aneurysms (Debakay type Ⅲ ) and eleven aortic sclerosis. SSD showed the body of aneurysm and the relationship between aneurysm and adjacent blood vessel, MIP better displayed calcification of blood vessel wall and condition of the stent, MPR demonstrated true and false lumen, rupture site of abdominal aorta intima and mural thrombus. Conclusion: MSCTA axial and reconstruction image can show the extent of abdominal aortic disease and the relationship with adjacent blood vessels. It is a safe, simple and non-invasive examination method.

  2. Clinical application of multi-slice spiral CT urography in traumatic urine leaka%外伤性尿漏多层螺旋CT诊断

    Institute of Scientific and Technical Information of China (English)

    俞国有

    2012-01-01

    Objective To explore the diagnostic value of multi-slice CT in the urine leakage. Methods 20 cases of urine leaks confirmed by clinical diagnosis underwent spiral CT plain scanning and triphasic dynamic enhancement scanning. The CT features on axial images and multiplanar reformation (MPR). maximum intensity projection (MIP) and volume rendering (VR) were reviewed. Results The breakage in renal parenchyma, subcapsular hematoma of kidney, prerenal fascia thickening appeared in 15 cases with pelvis leak affected by trauma. The excretory phase could detect 2 cases wfth ureteral leakage. 3 cases with bladder leak had the defect of posterior wall. Encapsulated effusion in rectal bladder space and eggshell-like calcification of the wall could be found, the contrast agent inpoured the urinary vesicle through the defect of the bladder wall. Conclusion Since the multi-slice CT urography (MSCT) examination clearly shows the leakage, the site of urine leakage. the scope of urinary vesicle. and other complications. it can be used as a preferred diagnostic method of urinary leakage.%目的 探讨多层螺旋CT对肾盂、输尿管及膀胱外伤性尿漏的诊断价值.方法 搜集20例经临床证实发生尿漏患者多层螺旋CT检查.全部行增强三期扫描.运用多种CT后处理技术(MPR、VR、MIP)综合分析其MSCT特点.结果 20例患者中,肾盂尿漏15例,输尿管尿漏2例,膀胱尿漏3例,排泄期表现为对比剂外渗,各种后处理技术可以清晰显示漏口的部位及范围,并可合并显示肝脾破裂、肾实质破裂、肾包膜下血肿、肾周间隙积液、骨盆多发骨折等.结论 MSCT延迟增强扫描能清晰显示尿漏的部位、漏口和并发症,对尿漏的诊断和选择治疗方案提供重要依据,可以作为尿漏诊断首选方法.

  3. Dynamic bowtie filter for cone-beam/multi-slice CT.

    Directory of Open Access Journals (Sweden)

    Fenglin Liu

    Full Text Available A pre-patient attenuator ("bowtie filter" or "bowtie" is used to modulate an incoming x-ray beam as a function of the angle of the x-ray with respect to a patient to balance the photon flux on a detector array. While the current dynamic bowtie design is focused on fan-beam geometry, in this study we propose a methodology for dynamic bowtie design in multi-slice/cone-beam geometry. The proposed 3D dynamic bowtie is an extension of the 2D prior art. The 3D bowtie consists of a highly attenuating bowtie (HB filled in with heavy liquid and a weakly attenuating bowtie (WB immersed in the liquid of the HB. The HB targets a balanced flux distribution on a detector array when no object is in the field of view (FOV. The WB compensates for an object in the FOV, and hence is a scaled-down version of the object. The WB is rotated and translated in synchrony with the source rotation and patient translation so that the overall flux balance is maintained on the detector array. First, the mathematical models of different scanning modes are established for an elliptical water phantom. Then, a numerical simulation study is performed to compare the performance of the scanning modes in the cases of the water phantom and a patient cross-section without any bowtie and with a dynamic bowtie. The dynamic bowtie can equalize the numbers of detected photons in the case of the water phantom. In practical cases, the dynamic bowtie can effectively reduce the dynamic range of detected signals inside the FOV. Furthermore, the WB can be individualized using a 3D printing technique as the gold standard. We have extended the dynamic bowtie concept from 2D to 3D by using highly attenuating liquid and moving a scale-reduced negative copy of an object being scanned. Our methodology can be applied to reduce radiation dose and facilitate photon-counting detection.

  4. 多层螺旋CT MPR、MIP及VRT剖切技术在腰椎峡部裂中的应用%Multi Slice Spiral CTMPR,MIP and VRT Cutting Technique in the Application of Iumbar Spondylolysis

    Institute of Scientific and Technical Information of China (English)

    公维云

    2013-01-01

    Objective:To investigate the multi-slice spiral CT post-processing method MPR,MIP and VRT combined cutting technique in lumbar spondylolysis application effect. Method:From October to 2012 in our hospital in 2010 August included 87 cases of lumbar spondylolysis with multi-slice spiral CT,and took MPR,MIP and VRT processing,to observe the effect of the clinical diagnosis. Result:Through the comparative analysis, of which,MPR and MIP display rate was 100%,while the VRT cutting front display rate was 94%,VRT after cutting display rate of 100%. Conclusion:Clinical application of lumbar spondylolysis patients taking spiral CT of the MPR,MIP and VRT cutting technology can effectively observed in patients with lesion site,MPR,MIP is the diagnosis of spondylolysis optimal method,three-dimensional sense of strong VRT.%  目的:探讨多层螺旋CT后处理方法MPR、MIP及VRT结合剖切技术在腰椎峡部裂中的应用效果。方法:选取本院2010年10月-2012年8月收治的87例腰椎峡部裂患者进行多层螺旋CT检查,并采取MPR、MIP及VRT进行处理,观察其临床诊断效果。结果:通过比较分析,其中,MPR和MIP的显示率均为100%,而VRT切割前显示率为94.0%,VRT切割后显示率为100%。结论:临床中腰椎峡部裂患者采取多层螺旋CT的MPR、MIP及VRT剖切技术能够有效的观察患者病变部位,MPR、MIP是诊断椎弓峡部裂的最佳方法,VRT的立体感较强。

  5. Peripheral pulmonary arteries: identification at multi-slice spiral CT with 3D reconstruction

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    Coche, Emmanuel; Pawlak, Sebastien; Dechambre, Stephane; Maldague, Baudouin [Department of Radiology, St. Luc Hospital, UCL, Avenue Hippocrate, 10, 1200 Brussels (Belgium)

    2003-04-01

    Our objective was to analyze the peripheral pulmonary arteries using thin-collimation multi-slice spiral CT. Twenty consecutive patients underwent enhanced-spiral multi-slice CT using 1-mm collimation. Two observers analyzed the pulmonary arteries by consensus on a workstation. Each artery was identified on axial and 3D shaded-surface display reconstruction images. Each subsegmental artery was measured at a mediastinal window setting and compared with anatomical classifications. The location and branching of every subsegmental artery was recorded. The number of well-visualized sub-subsegmental arteries at a mediastinal window setting was compared with those visualized at a lung window setting. Of 800 subsegmental arteries, 769 (96%) were correctly visualized and 123 accessory subsegmental arteries were identified using the mediastinal window setting. One thousand ninety-two of 2019 sub-subsegmental arteries (54%) identified using the lung window setting were correctly visualized using the mediastinal window setting. Enhanced multi-slice spiral CT with thin collimation can be used to analyze precisely the subsegmental pulmonary arteries and may identify even more distal pulmonary arteries. (orig.)

  6. Peripheral pulmonary arteries: identification at multi-slice spiral CT with 3D reconstruction.

    Science.gov (United States)

    Coche, Emmanuel; Pawlak, Sebastien; Dechambre, Stéphane; Maldague, Baudouin

    2003-04-01

    Our objective was to analyze the peripheral pulmonary arteries using thin-collimation multi-slice spiral CT. Twenty consecutive patients underwent enhanced-spiral multi-slice CT using 1-mm collimation. Two observers analyzed the pulmonary arteries by consensus on a workstation. Each artery was identified on axial and 3D shaded-surface display reconstruction images. Each subsegmental artery was measured at a mediastinal window setting and compared with anatomical classifications. The location and branching of every subsegmental artery was recorded. The number of well-visualized sub-subsegmental arteries at a mediastinal window setting was compared with those visualized at a lung window setting. Of 800 subsegmental arteries, 769 (96%) were correctly visualized and 123 accessory subsegmental arteries were identified using the mediastinal window setting. One thousand ninety-two of 2019 sub-subsegmental arteries (54%) identified using the lung window setting were correctly visualized using the mediastinal window setting. Enhanced multi-slice spiral CT with thin collimation can be used to analyze precisely the subsegmental pulmonary arteries and may identify even more distal pulmonary arteries.

  7. Application Research on Multi-slice Spiral CT Perfusion Imaging in Patients with Acute Cerebral Infarction%多层螺旋 CT 灌注成像在急性脑梗死患者的应用研究

    Institute of Scientific and Technical Information of China (English)

    罗友琛

    2014-01-01

    目的:探讨急性脑梗死患者多层螺旋 CT 灌注成像特点,及其与临床预后的关系。方法选择符合标准的患者40例,行 CT 灌注成像检查,计算脑血流量(CBF)、脑血容量(CBV)、平均通过时间(MTT)及峰值时间(TTP);分别在入院时和治疗后14d 采用美国国立卫生研究院卒中量表(NIHSS)评价临床神经功能缺损,计算缺血脑组织的可恢复比率(PRR)和神经功能恢复比率。结果脑梗死病灶中心 CBV 及 CBF 最低,健侧最高,而缺血半暗带居中,差异有统计学意义(P 0.05);PRR 与患者治疗14d 时 NIHSS 评分存在负相关性(r =-0.340, P 0. 05),negatively dependent of those at day 14 after treatment (r = - 0. 340,P < 0. 05) and positive-ly dependent of patient’s neural functional recovery ratio (r = 0. 467,P < 0. 05). Conclusion Multi-slice spiral CT perfusion im-aging can reflecthemodynamic changes in acute cerebral infarction lesions and their perihemodynamic changes. PRR is closely de-pendent of the neural functional recovery. It can serve as a reliable theoretical basis for clinical treatment.

  8. Small intestinal lipomas:Diagnostic value of multi-slice CT enterography

    Institute of Scientific and Technical Information of China (English)

    2010-01-01

    AIM:To analyze the clinical and imaging features of the small intestinal lipomas and to evaluate the diagnostic value of multi-slice computed tomography(CT) enterography.METHODS:Fourteen cases(one had two intestinal lesions) of surgically confirmed lipomas of the small intestine were retrospectively analyzed.The location,size,clinical and radiological aspects were discussed.RESULTS:Twelve patients presented with abdominal pain,of whom three complained of paroxysmal colic.Melena or bloody stools was mentione...

  9. Diagnosis of lower gastrointestinal bleeding by multi-slice CT angiography: A meta-analysis.

    Science.gov (United States)

    He, Bosheng; Yang, Jushun; Xiao, Jing; Gu, Jinhua; Chen, Feixiang; Wang, Lin; Zhao, Chengjin; Qian, Junbo; Gong, Shenchu

    2017-08-01

    To estimate the diagnostic value of multi-slice spiral CT angiography (CTA) in lower gastrointestinal bleeding by a meta-analysis. The relevant clinical studies on the diagnostic value of CTA were searched on PubMed, Embase and other electronic documents databases with the deadline of 2016 September. Language was limited to English. A diagnostic meta-analysis was performed by using Meta-DiSc software. The effect sizes included sensitivity, specificity, positive likelihood ratio (PLR), negative likelihood ratio (NLR), and diagnostic odds ratio (DOR) and 95% confidence interval (CI). The Cochran-Q test and I(2) statistic based on χ(2) test were used for estimation of the heterogeneity. Meta-regression was performed to explore the source of heterogeneity. SROC curve was established. A total of 14 articles including 549 patients with lower gastrointestinal bleeding were enrolled in the meta-analysis. The combined PLR, NLR and DOR were respectively 8.149, 0.158 and 56.213. There were significant heterogeneities in all estimations but we could not find the sources by meta-regression based on study design, study location, CT slices and sample size. The AUC and Q index under the fixed effect model was respectively 0.9463 and 0.8856. The multi-slice CTA has high diagnostic value for lower gastrointestinal bleeding. Copyright © 2017 Elsevier B.V. All rights reserved.

  10. 多层螺旋CT后处理技术在诊断肺隔离症中的应用%Application of Multi-slice Spiral CT Post-processing Technique in the Diagnosis of Pulmonary Sequestration

    Institute of Scientific and Technical Information of China (English)

    杨珂

    2015-01-01

    目的:探讨多层螺旋CT(MSCT)增强簿层扫描及图像后处理技术在肺隔离症(PS)的诊断价值。方法分析经临床手术病理、主动脉造影证实的21例肺隔离症患者的胸部多层螺旋CT平扫及CTA检查,并进行多平面重建(MPR)、最大密度投影法重建(MIP)、容积重建(VR)。结果21例病例均为单发,肺隔离症(PS)位于左肺下叶14例,右肺下叶7例;表现为肺野内团片、实性肿块者15例,囊样病灶者6例;21例孕杂的供血动脉均来自自体动脉,其中18例来自胸主动脉分支,3例来自腹主动脉。结论多层螺旋CT(MSCT)后处理技术能较准确、直观显示肺隔离症的供血动脉,可以取代有创DSA检查。%Objective To evaluate the multi-slice spiral CT (MSCT) reinforced thin layer scanning and image processing technique in the diagnosis of pulmonary sequestration (PS) value. Methods Analysis the clinical operation pathology, aortic angiography confirmed 21 cases of chest multi-slice spiral CT plain scan and CTA of pulmonary sequestration were examined, multi planar reconstruction (MPR), and the reconstruction of maximum intensity projection (MIP), volume rendering (VR). Results 21 cases were solitary, pulmonary sequestration (PS) located in the left lower lobe in 14 cases, right pulmonary lower lobe in 7 cases;for the performance of lung field of tanacu, solid mass in 15 cases, 6 cases of cystic lesion; artery in 21 cases of PS were derived from autologous artery, including 18 cases from aortic branch, 3 cases from the abdominal aorta. Conclusion Multi slice spiral CT (MSCT) after treatment technology can accurately, visual display of pulmonary sequestration artery, can replace invasive DSA examination.

  11. Clinical application of dental panoramic imaging by multi-slice spiral CT%多排螺旋CT全景齿科成像技术的临床价值探讨

    Institute of Scientific and Technical Information of China (English)

    徐刚; 胡海菁; 徐新超; 杜丽云

    2011-01-01

    目的 探讨多排螺旋CT(MSCT)全景齿科成像技术的临床应用价值.方法 对38例患者的牙齿、颌骨部位的容积数据进行后处理,重建出全景齿科图像和牙槽骨的矢状面和冠状曲面图像,与原始图像结合,对牙科疾病进行分析.结果 行MSCT检查的38例口腔疾病患者中,均能全方位立体再现齿科全貌:包括牙冠、牙体、牙根、牙髓腔的局部细节以及牙齿排列及咬合关系,可以从多个角度完整地显示了单个牙体的表面形态、各牙所在的位置、倾斜角度以及各牙之间的距离、牙列的整体形态和牙根的走行方向.结论 多排螺旋CT全景齿科成像可对牙、颌骨内微小病变的诊断治疗提供重要的客观依据,为牙科疾病提供了一种新的先进的检查手段及诊断方法.%Objective To investigate the clinical application of dental panoramic imaging by multi-slice spiral CT (MSCT).Methods Dental panoramic images, coronal and sagittal images of alveolar bone were reconstructed from initial data of tooth and jaw MSCT scanning in 38 patients with oral disease, and the results were compared with original images.Results All these 38 patients accepted MSCT scaning, the panorama of dental could be display clearly, including local details of the crown, dental body, root and pulp cavity, the teeth alignment and occlusal relationship.The surface morphology of each single dental body, the location, inclination angle and distance of each tooth, the dentural integral shape and the root walking direction could be displayed completely.Conclusions As an advanced examinational means and diagnosis method, dental panoramic imaging by MSCT could provide important objective basis?for clinical diagnosis and treatment of minute lesion of the tooth and jaw.

  12. Computer aided diagnosis of osteoporosis using multi-slice CT images

    Science.gov (United States)

    Takahashi, Eiji; Saita, Shinsuke; Kawata, Yoshiki; Niki, Noboru; Ito, Masako; Nishitani, Hiromu; Moriyama, Noriyuki

    2010-03-01

    The patients of osteoporosis comprised about 11 million people in Japan and it is one of the problems the aging society has. In order to prevent the osteoporosis, it is necessary to do early detection and treatment. The development of Multislice CT technology made it possible to perform the three dimensional (3-D) image analysis with higher body axis resolution and shorter scan time. The 3-D image analysis using multi-slice CT images of thoracic vertebra can be used as a support to diagnose osteoporosis and at the same time can be used for lung cancer screening which may lead to its early detection. We develop an automatic extraction algorithm of vertebra, and the analysis algorithm of the vertebral body using shape analysis and a bone density measurement for the computer aided diagnosis of osteoporosis.

  13. Modelling the Siemens SOMATOM Sensation 64 Multi-Slice CT (MSCT) Scanner

    Science.gov (United States)

    Amin, A. T. Mohd; Rahni, A. A. Abd

    2017-05-01

    Reconstructing large volumetric 3D images with minimal radiation dosage exposure with reduced scanning time has been one of the main objectives in the advancement of CT development. One of its advancement is the introduction of multi-slice arc detector geometry from a cone-beam source in third generation scanners. In solving this complex geometry, apart from the known vast computations in CT image reconstruction due to large CT images, iterative reconstruction methods are preferred compared to analytic methods due to its flexibility in image reconstruction. A scanner of interest that has this type of geometry is the Siemens SOMATOM Sensation 64 Multi-Slice CT (MSCT) Scanner, which has a total of 32 slices with 672 detector elements on each slice. In this paper, the scanner projection is modelled via the intersecting lengths between each ray (exhibited from the source to the detector elements) with the scanned image voxels, which are evaluated using the classical Siddon’s algorithm to generate the system matrix, H. This is a prerequisite to perform various iterative reconstruction methods, which involves solving the inverse problem arising from the linear equation: S = H· I; where S is the projections produced from the image, I. Due to the ‘cone-beam geometry’ along the z-axis, the effective field-of-view (FOV) with voxel dimensions (0.4×0.4×0.4) mm3 is 512×512×32 voxels. The scanner model is demonstrated by reconstructing an image from simulated projections using the analytic Feldkamp-Davis-Kress (FDK) method against basic iterative image reconstruction methods.

  14. Multi-slice CT for visualization of acute pulmonary embolism: single breath-hold subtraction technique

    Energy Technology Data Exchange (ETDEWEB)

    Wildberger, J.E.; Mahnken, A.H.; Spuentrup, E.; Guenther, R.W. [Dept. of Diagnostic Radiology, Univ. of Technology, Aachen (Germany); Klotz, E.; Ditt, H. [Siemens Medical Solutions, Computed Tomography, Forchheim (Germany)

    2005-01-01

    Purpose: the purpose of our preliminary animal study was to evaluate the feasibility of a new subtraction technique for visualization of perfusion defects within the lung parenchyma in segmental and subsegmental pulmonary embolism (PE). Materials and methods: in three healthy pigs, PE were artificially induced by fresh human clot material. Within a single breath-hold, CT angiography (CTA) was performed on a 16-slice multi-slice CT scanner (SOMATOM Sensation 16; Siemens, Forchheim, Germany) before and after intravenous application of 80 mL of contrast-medium, followed by a saline chaser. Scan parameters were 120 kV and 100 mAs{sub eff.}, using a collimation of 16 x 1.5 mm and a table speed/rot. of 36 mm (pitch: 1.5; rotation time: 0.5 s). A new 3D subtraction technique was developed, which is based on automated segmentation, non-linear spatial filtering and non-rigid registration. Data were analysed using a color-encoded ''compound view'' of parenchymal enhancement and CTA information displayed in axial, coronal and sagittal orientation. Results: subtraction was technically feasible in all three data sets. The mean scan time for each series was 4.7 s, interscan delay was 14.7 s, respectively. Therefore, an average breath-hold of approximately 24 s was required for the overall scanning procedure. Downstream of occluded segmental and subsegmental arteries, perfusion defects were clearly assessable, showing lower or missing enhancement compared to normally perfused lung parenchyma. In all pigs, additional peripheral areas with triangular shaped perfusion defects were delineated, considered typical for PE. Conclusions: our initial results from the animal model studied slow that perfusion imaging of PE is feasible within a single breath-hold. It allows a comprehensive assessment of perfusion deficits as the direct proof of a pulmonary embolus, can be combined with an indirect visual quantification of the density changes in the adjacent lung tissue

  15. A Hybrid Method for Segmentation and Visualization of Teeth in Multi-Slice CT scan Images

    Directory of Open Access Journals (Sweden)

    Mohammad Hosntalab

    2009-12-01

    Full Text Available Introduction: Various computer assisted medical procedures such as dental implant, orthodontic planning, face, jaw and cosmetic surgeries require automatic quantification and volumetric visualization of teeth. In this regard, segmentation is a major step. Material and Methods: In this paper, inspired by our previous experiences and considering the anatomical knowledge of teeth and jaws, we propose a hybrid technique for teeth segmentation and visualization in CT volumetric data. The major steps of the proposed techniques are as follows: (1 Separation of teeth in CT dataset; (2 Initial segmentation of teeth in panoramic projection; (3 Final segmentation of teeth in CT dataset; (4 3D visualization of teeth. Results: The proposed algorithm was evaluated in 30 multi-slice CT datasets. Segmented images were compared with manually outlined contours. In order to evaluate the proposed method, we utilized several common performance measures such as sensitivity, specificity, precision, accuracy and mean error rate. The experimental results reveal the effectiveness of the proposed method. Discussion and Conclusion: In the proposed algorithm, the variationallevel set technique was utilized to trace the contour of the teeth. In view of the fact that this technique is based on the characteristics of the overall region of the tooth image, it is possible to extract a very smooth and accurate tooth contour using this technique. For the available datasets, the proposed technique was more successful in teeth segmentation compared to previous techniques.

  16. Contrast investigation of multi-slice spiral CT perfusion imaging and pathological findings in VX2 soft-tissue tumor of rabbits

    Institute of Scientific and Technical Information of China (English)

    Jingfeng Zhang; Renfa Wang; Min Wang; Jing Zhang; Jinmei Sang

    2005-01-01

    Objective: To perform a contrast investigation of multi-slice spiral CT (MSCT) perfusion imaging and pathological findings in VX2 soft-tissue tumor of rabbits, and discuss the applicative value of multi-slice spiral CT perfusion imaging in soft-tissue tumors. Methods: 8 Newzealand white rabbits were implanted with 0.1 ml VX2 tumor tissue suspension in bilateral proximal thighs. 14 days and 21 days later, CT plain scan and perfusion scan were performed on these rabbits respectively, then the images were transmitted to AW4.0 workstation, the functional maps and perfusion parameters including blood flow (BF), blood volume (BV), mean transit time(MTT) and permeability surface (PS) were computed and analyzed. Subsequently, the rabbits were sacrificed, the tumors of which were taken out for pathological examination. The correlation between MSCT functional parametric images and pathological findings was analyzed.Results: All the values of BF, BV and PS of VX2 soft-tissue tumors were obviously higher while the MTT-values were lower than those of the normal muscular tissues significantly ( P < 0.001). Conclusion: Multi-slice spiral CT perfusion imaging is an accurate, convenient and relatively safe functional imaging technique, which can give a quantitative assessment to blood perfusion and angiogenesis of soft-tissue tumors.

  17. Experimental Study of Multi-slice Spiral CT Perfusion Imaging in VX2 Soft-tissue Tumor of Rabbits

    Institute of Scientific and Technical Information of China (English)

    ZHANG Jingfeng; WANG Renfa; WANG Min; LI Yonggang; YANG Haitao

    2006-01-01

    An experimental animal model of malignant soft-tissue tumor was established to investigate the applied value of multi-slice spiral CT perfusion imaging preliminarily. Ten New Zealand white rabbits which were implanted with VX2 tumor in either proximal thigh were subjected to CT plain scan and perfusion scan two weeks later respectively, then the original perfusion images were transmitted to AW4.0 Workstation. The functional maps and perfusion parameters including blood flow (BF), blood volume (BV), mean transit time (MTT) and permeability surface (PS) were computed and analyzed. All the values of BF, BV and PS in VX2 soft-tissue tumors were obviously higher while the MTT-values were lower than those in the normal muscular tissues significantly. It was suggested that multi-slice spiral CT perfusion imaging is an accurate, convenient and relatively safe functional imaging technique, and can give a quantitative assessment to angiogenesis and blood perfusion of soft-tissue tumors.

  18. [Diagnostic values of bronchoscopy and multi-slice spiral CT for congenital dysplasia of the respiratory system in infants: a comparative study].

    Science.gov (United States)

    Wang, Xing-Lu; Huang, Ying; Li, Qu-Bei; Dai, Ji-Hong

    2013-09-01

    To investigate and compare the diagnostic values of bronchoscopy and multi-slice spiral computed tomography (CT) for congenital dysplasia of the respiratory system in infants. Analysis was performed on the clinical data, bronchoscopic findings and multi-slice spiral CT findings of 319 infants (≤1 years old) who underwent bronchoscopy and/or multi-slice spiral CT and were diagnosed with congenital dysplasia of the respiratory system. A total of 476 cases of congenital dysplasia of the respiratory system were found in the 319 infants, including primary dysplasia of the respiratory system (392 cases) and compressive dysplasia of the respiratory system (84 cases). Of the 392 cases of primary dysplasia of the respiratory system, 225 (57.4%) were diagnosed by bronchoscopy versus 167 (42.6%) by multi-slice spiral CT. There were significant differences in etiological diagnosis between bronchoscopy and multi-slice spiral CT in infants with congenital dysplasia of the respiratory system (Pdysplasia of the respiratory system caused by tracheobronchomalacia were diagnosed by bronchoscopy and all 17 cases of primary dysplasia of the respiratory system caused by lung tissue dysplasia were diagnosed by multi-slice spiral CT. Of the 84 cases of compressive dysplasia of the respiratory system, 74 cases were diagnosed by multi-slice spiral CT and only 10 cases were diagnosed by bronchoscopy. Compared with multi-slice spiral CT, bronchoscopy can detect primary dysplasia of the respiratory system more directly. Bronchoscopy is valuable in the confirmed diagnosis of tracheobronchomalacia. Multi-slice spiral CT has a higher diagnostic value for lung tissue dysplasia than bronchoscopy.

  19. The Application of Multi-slice Spiral CT and MRI in Diagnosis of Facial Paralysis%CT、MRI在周围性面瘫诊断中的应用

    Institute of Scientific and Technical Information of China (English)

    汪建华; 田建明; 左长京; 马小龙; 王志锋; 曾新力

    2011-01-01

    目的 探讨多层螺旋CT与MRI技术在周围性面瘫的定位及病因诊断中的价值.方法 回顾性分析68例周围性面瘫患者的CT、MRI资料,分析总结影像学在周围性面瘫的定位、定性诊断中的意义.结果 本组68例周围性面瘫中影像学能明确定位45例(66.2%).病因分别是耳部先天畸形时伴面神经管异常2例,外伤性面瘫25例,慢性中耳乳突炎合并胆脂瘤10例,肿瘤11例及Bell's面瘫20例.除Bell's面瘫影像学无异常发现外,其他均准确发现病变并提示诊断.结论 合理运用CT、MRI技术,对耳部先天性发育畸形、脑外伤、慢性中耳乳突炎及肿瘤所致的周围性面瘫具有重要的诊断意义.%Objective To investigate the value of multi-slice spiral CT and MRI in diagnosis of pcripheral facial paralysis . Methods Imaging data of 68 patients with peripheral facial paralysis were analyzed retrospectively. The values of CT and MRI in localizing and qualitative diagnosing peripheral facial paralysis were summarized. Results In present study,45 of 68 cases(66. 2% ) of peripheral facial paralysis could be evaluated accurately in the etiology by CT and MRI,including congenital malformations of ear ( n= 2 ) ,traumatic facial paralysis ( n= 25) , chronic tympanitis with cholestcatoma( n= 10) and tumors( n= 11 ) , but Bell ' s facial paralysis ( n=20) was no of positive imaging findings . Conclusion CT and MRI are of significance for congenital ear deformities, traumaticbrain injury, chronic tympanitis with cholesteatomas , and tumors-induced peripheral facial paralysis.

  20. Multi-slice CT in the planning of nephron-sparing interventions for renal cell carcinoma: prospective study correlated with histopathology; Multi-Slice-CT in der Planung der organerhaltenden Operation des Nierenzellkarzinoms: Prospektive histopathologisch korrelierte Studie

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    Hallscheidt, P. [Forschungsschwerpunkt Radiologische Diagnostik und Therapie des Deutschen Krebsforschungszentrums, Heidelberg (Germany); Abt. Radiodiagnostik der Radiologischen Klinik der Univ. Heidelberg (Germany); Schoenberg, S.; Zuna, I. [Forschungsschwerpunkt Radiologische Diagnostik und Therapie des Deutschen Krebsforschungszentrums, Heidelberg (Germany); Schenk, J.P. [Abt. Radiodiagnostik der Radiologischen Klinik der Univ. Heidelberg (Germany); Petirsch, O.; Riedasch, G. [Urologische Klinik und Poliklinik der Univ. Heidelberg (Germany)

    2002-07-01

    Objective: For nephron sparing surgery of renal cell carcinoma knowledge of the intrarenal extension of the tumor and infiltration of the renal pelvis, the intrarenal vessels and the perinephric fat is essential. This question is much more difficult to answer compared to the description of staging parameters. Aim of this study is to evaluate the value of multi-slice CT in planning of nephron sparing surgery. Material and Methods: In a prospective study 46 patients with suspected renal cell carcinoma underwent a triphasic multi-slice CT (unenhanced, delay 30 s and 120 s). A reconstructed slice thickness of 2 mm in the arterial and parenchymal phase was used to create volume rendered 3D-reconstructions. Based on the source data and multiplanar reconstructed images the extent of the renal cell carcinoma was assessed in terms of size, hilar infiltration, arterial and venous invasions, capsula infiltration and perirenal growth. The results of two blinded readers were correlated with histopathological staging and intraoperative findings. Results: 36 carcinomas were evaluated histopathologically. 10 patients showed no renal cell carcinoma histopatholologically. Multi-slice CT allowed us to diagnose the localization and size of all tumors correctly. Infiltration into perinephric fat was correctly excluded in 24/30 and 8/30 cases. Infiltration of the renal pelvis could be excluded in 17/24 and 12/24 cases. The state of venous infiltration could be correctly diagnosed in 29/30 and 27 /30 carcinomas. Conclusion: Despite of the high temporal and spatial resolution of multi-slice CT, which allows the delineation of intrarenal arteries as well as renal hilus and the veins, the evaluation of tumor infiltration into the renal hilus, the intrarenal vessels and the perinephric fat remains a diagnostic problem. For planning of nephron sparing surgery, a knowledge of the infiltration in these structures is essential. (orig.) [German] Ziel: Fuer die Planung der organerhaltenden

  1. Multi-slice CT angiography by triple-phase enhancement in preoperative evaluation of hepatocellular carcinoma

    Institute of Scientific and Technical Information of China (English)

    XIAO Xi-gang; HAN Xue; SHAN Wei-dong; LI An-yuan

    2005-01-01

    Background Triple-phase enhancement of multi-slice computed tomography (MSCT) has markedly improved the diagnostic accuracy of hepatocellular carcinoma (HCC), and MSCT angiography (MSCTA) has been proved useful in detecting vascular anatomy noninvasively. This study aimed to explore the value of MSCTA by triple-phase enhancement in preoperative evaluation of HCC.Methods Fifty-six consecutive cases of primary HCC scheduled for resection were studied with MSCTA by triple-phase enhancement. The raw data images were processed on a workstation for multiplanar reconstruction (MPR) and three-dimensional (3D) reconstruction. The findings after processing of the data were compared with those after surgery or intraoperative sonography. Results The false positive rate of MSCTA by triple-phase enhancement was 10.1% and its false negative rate was 4.3% in detecting HCC. No significant difference was observed in MSCTA and surgery or intraoperative sonography in detecting vascular anatomy anomalies and pathologic variations, whereas significant difference was found in detecting bile duct invasion with MSCT compared to intraoperative sonography.Conclusions MSCTA by triple-phase enhancement not only improves the detection of HCC, but also provides valuable preoperative information about hepatic vascular architecture and parenchyma. MSCTA by triple-phase enhancement is worthy of application as a non-invasive method in preoperative evaluation of HCC.

  2. A comparative evaluation of Cone Beam Computed Tomography (CBCT) and Multi-Slice CT (MSCT)

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    Liang Xin, E-mail: Xin.Liang@med.kuleuven.b [Oral Imaging Centre, School of Dentistry, Oral Pathology and Maxillofacial Surgery, Faculty of Medicine, Catholic University of Leuven (Belgium); College of Stomatology, Dalian Medical University (China); Jacobs, Reinhilde, E-mail: Reinhilde.Jacobs@uz.kuleuven.b [Oral Imaging Centre, School of Dentistry, Oral Pathology and Maxillofacial Surgery, Faculty of Medicine, Catholic University of Leuven (Belgium); Hassan, Bassam, E-mail: b.hassan@acta.n [Department of Oral Radiology, Academic Centre for Dentistry Amsterdam (ACTA), Amsterdam (Netherlands); Li Limin, E-mail: Limin.Li@uz.kuleuven.b [Department of Paediatric Dentistry and Special Dental Care, School of Dentistry, Oral Pathology and Maxillofacial Surgery, Faculty of Medicine, Catholic University of Leuven (Belgium); Pauwels, Ruben, E-mail: Ruben.Pauwels@med.kuleuven.b [Oral Imaging Centre, School of Dentistry, Oral Pathology and Maxillofacial Surgery, Faculty of Medicine, Catholic University of Leuven (Belgium); Corpas, Livia, E-mail: LiviaCorpas@gmail.co [Oral Imaging Centre, School of Dentistry, Oral Pathology and Maxillofacial Surgery, Faculty of Medicine, Catholic University of Leuven (Belgium); Souza, Paulo Couto, E-mail: Paulo.CoutoSouza@med.kuleuven.b [Oral Imaging Centre, School of Dentistry, Oral Pathology and Maxillofacial Surgery, Faculty of Medicine, Catholic University of Leuven (Belgium); Martens, Wendy, E-mail: wendy.martens@uhasselt.b [Department of Basic Medical Sciences, Faculty of Medicine, University of Hasselt, Diepenbeek (Belgium); Shahbazian, Maryam, E-mail: Maryam.Shahbazian@student.kuleuven.b [Oral Imaging Centre, School of Dentistry, Oral Pathology and Maxillofacial Surgery, Faculty of Medicine, Catholic University of Leuven (Belgium); Alonso, Arie, E-mail: ariel.alonso@uhasselt.b [Department of Biostatistics and Statistical Bioinformatics, Universiteit Hasselt (Belgium)

    2010-08-15

    Aims: To compare image quality and visibility of anatomical structures in the mandible between five Cone Beam Computed Tomography (CBCT) scanners and one Multi-Slice CT (MSCT) system. Materials and methods: One dry mandible was scanned with five CBCT scanners (Accuitomo 3D, i-CAT, NewTom 3G, Galileos, Scanora 3D) and one MSCT system (Somatom Sensation 16) using 13 different scan protocols. Visibility of 11 anatomical structures and overall image noise were compared between CBCT and MSCT. Five independent observers reviewed the CBCT and the MSCT images in the three orthographic planes (axial, sagittal and coronal) and assessed image quality on a five-point scale. Results: Significant differences were found in the visibility of the different anatomical structures and image noise level between MSCT and CBCT and among the five CBCT systems (p = 0.0001). Delicate structures such as trabecular bone and periodontal ligament were significantly less visible and more variable among the systems in comparison with other anatomical structures (p = 0.0001). Visibility of relatively large structures such as mandibular canal and mental foramen was satisfactory for all devices. The Accuitomo system was superior to MSCT and all other CBCT systems in depicting anatomical structures while MSCT was superior to all other CBCT systems in terms of reduced image noise. Conclusions: CBCT image quality is comparable or even superior to MSCT even though some variability exists among the different CBCT systems in depicting delicate structures. Considering the low radiation dose and high-resolution imaging, CBCT could be beneficial for dentomaxillofacial radiology.

  3. Assessment of the arteriovenous cerebrovascular system by multi-slice CT. A single-bolus, monophasic protocol

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    Klingebiel, R.; Zimmer, C. [Charite CM, Humboldt Univ., Berlin (Germany). Neuroradiology Section; Rogalla, P.; Kivelitz, D. [Charite CM, Humboldt Univ., Berlin (Germany). Dept. of Radiology; Bohner, G. [Charite CM, Humboldt Univ., Berlin (Germany). Neuroradiology Section; Goetze, R. [Charite CM, Humboldt Univ., Berlin (Germany). Dept. of Radiology; Lehmann, R. [Charite CM, Humboldt Univ., Berlin (Germany). Neuroradiology Section

    2001-11-01

    Purpose: We present a protocol for the non-invasive angiographic assessment of the arterial and venous cerebrovascular (CV) system by multi-slice CT. Material and Methods: Data acquisition was performed in a multi-slice CT scanner with a scan range from the carotid bifurcation to the vertex and manual scan start following i.v. administration of 120 ml iodinated contrast medium with a flow rate of 4 ml/s. This protocol was applied in 12 patients with symptoms of acute CV insufficiency. Results: In all patients, comprehensive imaging of the arteriovenous CV system was achieved including the common carotid bifurcation, the third segment of the major cerebral arteries, the dural sinus and the internal cerebral veins. Various CV pathologies, such as a territorial artery occlusion, a thrombotic obstruction of the internal carotid artery, an intracranial arteriovenous malformation and a sinus vein thrombosis, were successfully evaluated. Conclusion: Comprehensive assessment of the arteriovenous CV system is possible by the use of a single-bolus, monophasic multi-slice scan technique.

  4. Peripheral pulmonary nodules: Relationship between multi-slice spiral CT perfusion imaging and tumor angiogenesis and VEGF expression

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    Cheng Xiao-Ling

    2008-06-01

    Full Text Available Abstract Background The aim of this study is to investigate the relationship between16-slice spiral CT perfusion imaging and tumor angiogenesis and VEGF (vascular endothelial growth factor expression in patients with benign and malignant pulmonary nodules, and differential diagnosis between benign and malignant pulmonary nodules. Methods Sixty-four patients with benign and malignant pulmonary nodules underwent 16-slice spiral CT perfusion imaging. The CT perfusion imaging was analyzed for TDC (time density curve, perfusion parametric maps, and the respective perfusion parameters. Immunohistochemical findings of MVD (microvessel density measurement and VEGF expression was evaluated. Results The shape of the TDC of peripheral lung cancer was similar to those of inflammatory nodule. PH (peak height, PHpm/PHa (peak height ratio of pulmonary nodule to aorta, BF (blood flow, BV (blood volume value of peripheral lung cancer and inflammatory nodule were not statistically significant (all P > 0.05. Both showed significantly higher PH, PHpm/PHa, BF, BV value than those of benign nodule (all P 0.05. In the case of adenocarcinoma, BV, BF, PS, PHpm/PHa, and MVD between poorly and well differentiation and between poorly and moderately differentiation were statistically significant (all P 0.05. PH, PHpm/PHa, BV, and PS of benign nodule were significantly lower than those of peripheral lung cancer (all P Conclusion Multi-slice spiral CT perfusion imaging closely correlated with tumor angiogenesis and reflected MVD measurement and VEGF expression. It provided not only a non-invasive method of quantitative assessment for blood flow patterns of peripheral pulmonary nodules but also an applicable diagnostic method for peripheral pulmonary nodules.

  5. 多层螺旋CT在腹股沟区解剖中的应用%Application of multi-slice spiral CT in the study of the anatomy of inguinal region

    Institute of Scientific and Technical Information of China (English)

    沈超; 张联合; 陈文辉; 俞一歆

    2011-01-01

    Objective:To evaluate multi-slice spiral CT (MSCT) with three-dimensional reconstruction techniques in the study of the anatomy of inguinal region. Methods: MSCT three-dimensional reconstruction images of inguinal region in order to display the inguinal ligament (IL) .inferior epigastric artery (IEA) and round ligament or spermatic cord on the axial, coronal,and sagittal views in 20 patients were retrospectively analyzed. Results:The inferior epigastric artery was identified in all planes of all 20 patients (100%). The inguinal ligament and the round ligament or spermatic cord could only be well identified on axial plane in 70% of 20 patients. On coronal views, the inguinal ligament could be revealed in 100%, whereas the round ligament or spermatic cord could only be showed in 77. 5 % of the patients. The inguinal ligament was Identifiable in 90% and the round ligament or spermatic cord in 72. 5% of the patients on sagittal view. Conclusion: Combination of the axial, coronal and sagittal reconstruction images of MSCT could display the key anatomic structures of inguinal region,and is significant in the diagnosis and classification of inguinal hernia.%目的:探讨多层螺旋CT三维重建在腹股沟区解剖的应用.方法:回顾性分析20例行多层螺旋CT腹股沟区扫描的三维重建图像,观察在横断面、冠状面及矢状面上腹股沟韧带、腹壁下动脉、圆韧带或精索的显示情况.结果:20例病例中腹壁下动脉在3个轴面上均能显示,显示率100%.横断面不能很好的显示腹股沟韧带,圆韧带或精索的显示率为70%.冠状面能100%显示腹股沟韧带,圆韧带或精索的显示率为77.5%.矢状面腹股沟韧带的显示率为90%,圆韧带或精索的显示率为72.5%.结论:结合多层螺旋CT重建的横断面、冠状面及矢状面图像能满意显示腹股沟区的关键解剖结构,对诊断分型腹股沟疝有较大意义.

  6. 多层螺旋CT在肠系膜上动脉栓塞诊断中的应用价值%Application of Multi-slice CT in the Diagnosis of Superior Mesenteric Artery Embolization

    Institute of Scientific and Technical Information of China (English)

    张银; 吴智玲; 周立强; 杨建平; 徐开鹏; 陈士花; 宋淮

    2013-01-01

    Objective To investigate the value of multi - slice CT ( MSCT ) in diagnosis of superior mesenteric artery embolization ( SMAE ) . Methods Clinical and imaging data of 18 SMAE patients admitted to our hospital from April 2006 to November 2011 were retrospectively analyzed to summarize the MSCT imaging characteristics of SMAE. Results All the 18 patients were given MSCT three - phase scan, and 11 patients were also given DSA test. The accuracy of MSCT in predicting trunk embolism of SMA was 100. 0% ( 13/13 ), while the accuracy of MSCT in predicting branch embolism was 60% ( 3/5 ), and 2 cases were suspected of SMAE and then confirmed by DSA. MSCT plain scan showed that the embolus was low density and could not be easily differentiated from normal SMA. 4 cases were combined with gut cavity expansion, but without seroperitoneum or intestinal obstruction. Enhancement scan showed that 13 cases had filling defects of SMA trunk, and dotted or oval enhanced shadow were seen in 6 incomplete SMA trunk embolism cases and filling defect shadow were seen in 5 complete branch embolism cases. Data post -processing and image reconstruction showed that volume rendering ( VR ) of the 13 SMA trunk embolism cases could well demonstrate space relationship and could well demonstrate the shape of blood vessels and their relationship with surroundings. MIP of the 3 cases showed the formation of plaque on blood vessel wall. Multi - planar reconstruction ( MPR ) and curve planar reformation ( CPR ) could demonstrate vessel lumen more directly. Conclusion MSCT and post - processing technology is non - invasive, and can diagnose SMAE rapidly and accurately, providing reliable information for assessing the condition of SMAE.%目的 探讨多层螺旋CT(MSCT)在肠系膜上动脉栓塞(SMAE)诊断中的应用价值.方法 回顾性分析我院2006年4月-2011年11月收治的18例SMAE患者的临床及影像学资料,总结SMAE的MSCT影像学特征.结果 18例

  7. Multi-slice spiral CT in routine diagnosis of suspected acute left-sided colonic diverticulitis: a prospective study of 120 patients

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    Werner, A.; Diehl, S.J.; Dueber, C. [Institut fuer Klinische Radiologie, Universitaetsklinikum Mannheim, Theodor-Kutzer-Ufer 1-3, 68167, Mannheim (Germany); Farag-Soliman, M. [Chirurgische Klinik, Universitaetsklinikum Mannheim, Theodor-Kutzer-Ufer 1-3, 68167, Mannheim (Germany)

    2003-12-01

    This prospective study evaluated the use of multi-slice CT (MSCT) for detection of clinically suspected left-sided colonic diverticulitis with regard to diagnosis, complications and alternative diagnoses. One hundred twenty patients with clinically suspected acute left-colonic diverticulitis underwent MSCT of the lower abdomen with IV contrast after rectal application of iodic contrast. The MSCT results were compared with histopathological and intraoperative findings or other radiological or endoscopic methods and clinical outcome. Acute diverticulitis was proven in 67 of the 120 (55.8%) patients, which was detected by MSCT with an accuracy of 98% (sensitivity 97%, specificity 98%). Contained perforation or abscess formation were detected with an accuracy of 96% (sensitivity 100%, specificity 91%) and 98% (sensitivity 100%, specificity 97%), respectively. In 31 of 120 (25.8%) patients diagnoses other than diverticulitis caused abdominal pain, which was correctly diagnosed by MSCT in 71%. The MSCT as well as other concurrently performed diagnostic methods showed normal findings and no causes for the patients symptoms in 22 of the 120 (18.4%) patients. Multi-slice CT is reliable in detecting diverticulitis, including extracolic complications, and often reveals other diagnoses; therefore, MSCT is recommended as standard diagnostic procedure in suspected acute diverticulitis. (orig.)

  8. 多层螺旋CT灌注成像在肾脏良恶性肿瘤鉴别诊断中的临床应用%Clinical Application of Multi - slice Spiral CT Perfusion Imaging in the Differential Diagnosis of Benign and Malignant Renal Tumors

    Institute of Scientific and Technical Information of China (English)

    赵红; 夏文平; 李培

    2012-01-01

    Objective To discuss the clinical practice value of multi - slice spiral CT perfusion imaging in the differential diagnosis of benign and malignant renal tumors. Methods Using multi - slice spiral CT machine, we detected the CT perfusion parameters of 20 cases of normal healthy volunteers(the control group) ,22 cases of renal clear cell carcinoma proved by operation (the renal carcinoma group) and 18 cases of renal hamarloma( the renal hamartoma group). Perfusion (perfusion) , relative blood volume (rBV) , time to peak (TTP) and peak enhancementimage (PEI) were obtained and calaculated. Results ①The perfusion,PEI of the renal carcinoma group Were significantly lower than thnse of the coutrol group, while the rBV.TTP were significantly higher than those of the control group; ② The perfusion, PEI of the renal hamarlunia group were significantly lower than those of the control group, while the rBV ,TTP of the renal hamanoma group were significantly higher than those of the control group; ③The perfusion .PEI of ihe renal carcinoma group were significantly higher than those of the renal hamartoma group, while the rBV,TTP of the renal carcinoma group were significantly lower lhan those of renal hamartoma group. The differences were significant statistically significant. Conclusion Multi - slice spiral CT perfusinn imaging can quantitatively assess hemortynamics variation of the normal kidney,benign and malignant renal tumors. It can provide a reliable hasis for differential diagnosis,which has important clinical application value.%目的 探讨多层螺旋CT(MSCTPI)灌注成像在肾脏良恶性肿瘤鉴别诊断中的应用价值.方法 采用多层螺旋CT机对正常健康志愿者20例(对照组)及经手术病理证实的肾透明细胞癌患者22例(肾癌组)、肾错构瘤患者18例(肾错构瘤组)的肾皮质CT灌注参数进行检测,分别计算:灌注(perfusion);相对组织血容量(rBV);峰值时间(TTP);峰值增强影像(PEI).结果 ①肾

  9. Imaging skeletal anatomy of injured cervical spine specimens: comparison of single-slice vs multi-slice helical CT

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    Obenauer, S.; Alamo, L.; Herold, T.; Funke, M.; Kopka, L.; Grabbe, E. [Department of Radiology, Georg August-University Goettingen, Robert-Koch-Strasse 40, 37075 Goettingen (Germany)

    2002-08-01

    Our objective was to compare a single-slice CT (SS-CT) scanner with a multi-slice CT (MS-CT) scanner in the depiction of osseous anatomic structures and fractures of the upper cervical spine. Two cervical spine specimens with artificial trauma were scanned with a SS-CT scanner (HighSpeed, CT/i, GE, Milwaukee, Wis.) by using various collimations (1, 3, 5 mm) and pitch factors (1, 1.5, 2, 3) and a four-slice helical CT scanner (LightSpeed, QX/i, GE, Milwaukee, Wis.) by using various table speeds ranging from 3.75 to 15 mm/rotation for a pitch of 0.75 and from 7.5 to 30 mm/rotation for a pitch of 1.5. Images were reconstructed with an interval of 1 mm. Sagittal and coronal multiplanar reconstructions of the primary and reconstructed data set were performed. For MS-CT a tube current resulting in equivalent image noise as with SS-CT was used. All images were judged by two observers using a 4-point scale. The best image quality for SS-CT was achieved with the smallest slice thickness (1 mm) and a pitch smaller than 2 resulting in a table speed of up to 2 mm per gantry rotation (4 points). A reduction of the slice thickness rather than of the table speed proved to be beneficial at MS-CT. Therefore, the optimal scan protocol in MS-CT included a slice thickness of 1.25 mm with a table speed of 7.5 mm/360 using a pitch of 1.5 (4 points), resulting in a faster scan time than when a pitch of 0.75 (4 points) was used. This study indicates that MS-CT could provide equivalent image quality at approximately four times the volume coverage speed of SS-CT. (orig.)

  10. Clinical application value of multi slice spiral CT in the variation of sinus and nasal complex and sinusitis diagnosis%多层螺旋CT对窦口鼻道复合体解剖变异及鼻窦炎诊断的临床应用价值

    Institute of Scientific and Technical Information of China (English)

    张爱军

    2016-01-01

    目的研究多层螺旋CT对窦口-鼻道复合体(OMC)变异及鼻窦炎诊断的临床应用价值。方法选取2014年5月~2015年4月我院收治的192例慢性鼻窦炎患者,其中40例行鼻内镜手术。经多层螺旋CT观察OMC的解剖变异、鼻窦炎症及鼻内镜技术在手术中的应用。结果192例慢性鼻窦炎症患者中,有164例(85.4%)为OMC解剖变异,其中泡状鼻甲30.21%(58/192),反常中鼻甲9.38%(18/192),钩突肥厚13.54%(25/192),钩突内侧偏移11.64%(22/192),钩突外侧偏移4.17%(8/192),钩突气化3.13%(6/192),Haller气房8.33%(16/192),鼻丘气房9.38%(18/192),鼻中隔偏曲25%(48/192)。鼻及鼻窦炎发病部位分布:前组筛窦168例,后组筛窦72例,上颌筛窦134例,上颌窦126例,额隐窝38例,额窦28例,碟窦16例。行鼻内镜手术患者术中所见和CT显示一致。结论慢性鼻窦炎患者OMC变异及解剖结构采取多层螺旋CT进行观察具有重要的价值,尤其是对功能性内镜鼻窦手术具有重要作用。%Objective To study the clinical applica-tion value of multi slice spiral CT in the variation of sinus and nasal complex(OMC)and sinusitis diagnosis.Methods From May 2014 to April 2015,192 cases with chronic sinusitis,including 40 cases underwent nasal endoscopic surgery were included in this study. OMC anatomical variations and sinusitis were observed by multi-slice spiral CT. Nasal sinus endoscope was used in the surgery. Results Of the 192 cases,164 cases(85.4%)were proved with OMC anatomical variations,including 30.21% concha bullosa, 9.38% abnormal middle turbinate,13.53% uncinate process hypertrophy,11.64% uncinate medial offset,4.17% lateral deviation of uncinate process,3.13%cuncinate gasification, 8.33% Haller cell and 9.38% agger nasi cell,and 25% nasal septum deviation. The nasal sinusitis distribution:168 cases of anterior ethmoid sinus,72 cases of ethmoid sinus,134 cases of

  11. Dynamic enhanced multi-slice spiral CT in evaluation of blood flow patterns of solitary pulmonary nodules with enhancement

    Institute of Scientific and Technical Information of China (English)

    LI Shenjiang; XIAO Xiangsheng; LIU Shiyuan; LI Huimin; LI Chengzhou; ZHANG Chenshi; TAO Zhiwei; YANG Chunshan

    2004-01-01

    Objective To investigate the methods of dynamic enhanced multi-slice spiral CT in evaluation of blood flow patterns of solitary pulmonary nodules (SPNs) with enhancement. Methods Seventy eight patients with SPNs (≤4 cm) with strong enhancement underwent dynamic multi-slice spiral CT (Marconi Mx8000) scan before and after contrast enhancement by injecting contrast material with a rate of 4 mL/s. For the 40 patients in protocol one, one scan was obtained every 2 seconds during 15-45 and 75- 105 seconds after injection, while for the 38 patients in protocol two, one scan was obtained every 2 seconds during 11-41 and 71-101 seconds. For all the patients, one scan was obtained every 30 seconds during 2 9 minutes. The section thickness was 2.5 mm for lesions ≤3 cm and 5 mm for lesions >3 cm. Standard algorithm was used in the image reconstruction. Precontrast and postcontrast attenuation on every scan was recorded. The perfusion,peak height, ratio of peak height of the SPN to that of the aorta and mean transit time were calculated. Results The peak height, perfusion, ratio of peak height of the SPN to that of the aorta and mean transit time in malignant SPNs were 34. 85 Hu±10.87 Hu, 30. 37 ml/(min· 100 g)±11. 14 ml/(min · 100 g), 13. 78%±3.96%, 14.19 s±6.19 s respectively in protocol one, while those in protocol two were 36.62 Hu±10.75 Hu,30.01 ml/(min · 100 g)±8.10 ml/(min · 100 g), 14.70 %±4.71%, 13.91 s±4.82 s respectively. No statistically significant differences were found between the peak height (t = 0. 673, P = 0. 503), perfusion (t =0.152, P=0.880), ratio of peak height of the SPN to that of the aorta (t 0.861, P 0.393) and mean transit time (t= 0. 199, P=0. 843) in malignant SPNs measured in protocol one and those measured in protocol two. All mean transit time in protocol two (36/36) were obtained, but only part of them (25/32) were ob tained in protocol one. Conclusion Dynamic enhanced multi-slice spiral CT is a non-invasive method for

  12. Studies on intracranial collateral circulation with multi-slice CT angiography in patients with symptomatic cerebral artery stenosis

    Directory of Open Access Journals (Sweden)

    Shu-qing ZHOU

    2011-06-01

    Full Text Available Objective To explore the features of intracranial collateral circulation in patients with symptomatic cerebral artery stenosis.Method Ninety-four patients with ischemic cerebrovascular disease admitted from Apr.2004 to Jun.2009 were involved in present study.All the patients were examined with cerebral multi-slice CT angiography,and the features of cerebral artery stenosis and intracranial collateral circulation were evaluated using maximum intensity projection(MIP and volume rendering(VR images of CT angiography.Result Of the 94 patients involved,48 were diagnosed as cerebral artery stenosis,including 29 cases of cerebral infarction,18 of transient ischemic attack(TIA and 1 of moyamoya disease(MMD.Among the 14 cases of severe cerebral artery stenosis or occlusion,cerebral infarction was found in 6 cases with lesser intracranial collateral vessels(including massive cerebral infarction in 4 cases and watershed infarction in 2 cases,and focal infarction of central semi-ovale in 1 case and TIA in 7 cases were found with abundant intracranial collateral vessels.Multiple lacunar infarction was found in 22 cases of mild or moderate cerebral artery stenosis,but there was no significant correlation between the stenosed arteries and infarction sites.Abundant intracranial collateral vessels were found in one patient with Moyamoya disease but no infarction was observed.Conclusions Intracranial collateral circulation plays an important role of compensation in patients with severe cerebral artery stenosis or occlusion.Cerebral angiography with multi-slice CT is of great significance in evaluation of cerebral artery stenosis and intracranial collateral circulation.

  13. 多层螺旋CT自动管电流调制技术及应用进展%Automatic Tube Current Modulation Techniques in Multi-slice CT Scanning and the Application Progress

    Institute of Scientific and Technical Information of China (English)

    王倩

    2013-01-01

    随着计算机X线断层扫描(CT)技术的普及,CT扫描的高辐射剂量日益得到广泛关注.CT低剂量研究也成为了CT研究的热点领域.目前,降低CT扫描剂量的方法众多,而自动管电流调制技术(ATCM)作为一项通过实时曝光控制优化辐射剂量兼顾图像质量的先进技术已在临床工作中应用.不同的设备各有其技术基本原理及指标.对ATCM技术在头颈、胸、腹、盆腔部位应用及其影响因素和局限性等尚需更多的临床研究和改进.%With the popularization of CT scanning technology,high radiation dose has drawn wide attention, and low-dose CT has become the hot field. Jnowdays,many methods could be used to reduce CT radiation dose. Automatic tube current modulationt (ATCM ) technique, an advanced technology, has been applied in the clinical which optimizes radiation dose through real-time exposure control with the guaranty for image quality. Different equipments have different working principles and indicators, and the application of ATCM technique in head and neck, thorax, abdomen, pelvic cavity and the influencers and limitations still need further clinical research and improvement.

  14. Application of the FDK algorithm for multi-slice tomographic image reconstruction; Aplicacao do algoritmo FDK para a reconstrucao de imagens tomograficas multicortes

    Energy Technology Data Exchange (ETDEWEB)

    Costa, Paulo Roberto, E-mail: pcosta@if.usp.b [Universidade de Sao Paulo (IFUSP), SP (Brazil). Inst. de Fisica. Dept. de Fisica Nuclear; Araujo, Ericky Caldas de Almeida [Fine Image Technology, Sao Paulo, SP (Brazil)

    2010-08-15

    This work consisted on the study and application of the FDK (Feldkamp- Davis-Kress) algorithm for tomographic image reconstruction using cone-beam geometry, resulting on the implementation of an adapted multi-slice computed tomography system. For the acquisition of the projections, a rotating platform coupled to a goniometer, an X-ray equipment and a digital image detector charge-coupled device type were used. The FDK algorithm was implemented on a computer with a Pentium{sup R} XEON{sup TM} 3.0 processor, which was used for the reconstruction process. Initially, the original FDK algorithm was applied considering only the ideal physical conditions in the measurement process. Then some artifacts corrections related to the projections measurement process were incorporated. The implemented MSCT system was calibrated. A specially designed and manufactured object with a known linear attenuation coefficient distribution ({mu}(r)) was used for this purpose. Finally, the implemented MSCT system was used for multi-slice tomographic reconstruction of an inhomogeneous object, whose distribution {mu}(r) was unknown. Some aspects of the reconstructed images were analyzed to assess the robustness and reproducibility of the system. During the system calibration, a linear relationship between CT number and linear attenuation coefficients of materials was verified, which validate the application of the implemented multi-slice tomographic system for the characterization of linear attenuation coefficients of distinct several objects. (author)

  15. A comparative evaluation of Cone Beam Computed Tomography (CBCT) and Multi-Slice CT (MSCT) Part I. On subjective image quality

    NARCIS (Netherlands)

    Liang, X.; Jacobs, R.; Hassan, B.; Li, L.M.; Pauwels, R.; Corpas, L.; Souza, P.C.; Martens, W.; Alonso, A.; Lambrichts, I.

    2010-01-01

    Aims: To compare image quality and visibility of anatomical structures in the mandible between five Cone Beam Computed Tomography (CBCT) scanners and one Multi-Slice CT (MSCT) system. Materials and methods: One dry mandible was scanned with five CBCT scanners (Accuitomo 3D, i-CAT, NewTom 3G, Galileo

  16. A comparative evaluation of Cone Beam Computed Tomography (CBCT) and Multi-Slice CT (MSCT). Part II: On 3D model accuracy

    NARCIS (Netherlands)

    Liang, X.; Lambrichts, I.; Sun, Y.; Denis, K.; Hassan, B.; Li, L.; Pauwels, R.; Jacobs, R.

    2010-01-01

    Aim: The study aim was to compare the geometric accuracy of three-dimensional (3D) surface model reconstructions between five Cone Beam Computed Tomography (CBCT) scanners and one Multi-Slice CT (MSCT) system. Materials and methods: A dry human mandible was scanned with five CBCT systems (NewTom 3G,

  17. Role of multi-slice CT coronary angiography in evaluating the different patterns of coronary artery disease in patients with unstable angina

    Directory of Open Access Journals (Sweden)

    Gamal Eldine M. Niazi

    2015-09-01

    Conclusion: Non-invasive multi-slice CT coronary angiography is a reliable technique of high ability to detect coronary artery disease and estimate the degree of obstruction, number of affected arteries and the pattern of their affection and can be used in workup in patients with unstable angina.

  18. Functional Study of the Heart using MRI and Multi-slice CT (MSCT

    Directory of Open Access Journals (Sweden)

    "Sh. Akhlaghpour

    2005-08-01

    Full Text Available Introduction & Background: By using newer imaging techniques (MRI and MSCT, it is possible to perform functional studies of the heart including, wall mo-tion, chamber volume evaluation, and myocardial mass and wall thickness. While MRI had recently been introduced as the gold standard method for the morphological and functional studies of the heart, recent advances in the number of detectors, rotation time, and reconstruction protocols made Multislice CT (MSCT another new application for functional studies of the heart too. Ordinary raw data for coro-nary CT angiography is sufficient for these functional studies. Apart from the point that which technique is to be used to get a standard and reproducible meas-urement, a proper imaging strategy is necessary. To use MSCT, various softwares are available for these studies. By the use of these two modalities, valvular evaluations are also possible as addressed in many recent publications. In this article the strategy for functional study of the heart is presented and some case studies are also discussed.

  19. 总结多层螺旋CT在创伤性上颈椎隐形损伤患者诊断中的应用体会%Summary of Multi-Slice Spiral CT in traumatic Upper Cervical Injury Patients Contact Experience Application in Diagnosis

    Institute of Scientific and Technical Information of China (English)

    魏波

    2015-01-01

    Objective: To explore the focus of traumatic upper cervical contact diagnosis value of multi-slice spiral CT in injury patients.Methods: the research object selected is 2011 02 Feb 01 to 2014 02 months 01 days in our hospital underwent multislice spiral CT examination of 56 patients with suspected in patients with upper cervical injury, detailed analysis of the results of image.Results: the display for the contact damage in a total of 45 patients, 4 patients belonged to the ring gear joint, 2 patients belonged to the vertebral rotation dislocation, 9 cases belong to C1 lateral mass fracture, 2 cases belong to the simple transverse ligament injury, atlas lateral mass fracture on the right side of a total of 3 cases of C1 fracture dislocation;accompanied by vertebral attachment a total of 2 cases of fracture of vertebral arch fracture C1, a total of 6 cases of vertebral fracture and dislocation; C2 with a total of 3 cases of accessory fracture, fracture C2 of vertebral arch of a total of 5 cases;C2 vertebral fracture accompanied by accessory fracture has a total of 3 cases, C2 a total of 6 cases of vertebral fracture, tooth styloid fractures with a total of 11 cases.Conclusion: multi slice spiral CT in the diagnosis of traumatic upper cervical application invisible injury high accuracy, can provide valuable references for clinical treatment.%目的:重点探索在创伤性上颈椎隐形损伤患者中应用多层螺旋CT的诊断价值。方法挑选的研究对象是2011年02月01日—2014年02月01日在我院行多层螺旋CT检查的56例疑似上颈椎损伤患者,细致的分析影像学结果。结果显示为隐形损伤的总共有45例,4例患者属于环齿关节,2例患者属于椎体旋转脱位,9例属于C1侧块骨折,2例属于单纯横韧带损伤,环椎右侧侧块骨折的总共有3例;C1骨折脱位并伴随椎体附件骨折的总共有2例,C1椎弓骨折的总共有6例;C2椎体骨折脱位并伴随附件骨折的总共有3

  20. Multi-slice myelin water imaging for practical clinical applications at 3.0 T.

    Science.gov (United States)

    Guo, Junyu; Ji, Qing; Reddick, Wilburn E

    2013-09-01

    Myelin water imaging is a promising, noninvasive technique for evaluating white matter diseases such as multiple sclerosis and other leukoencephalopathies (LE), and monitoring myelination in early childhood. Unfortunately, poor image quality and a long acquisition time are major obstacles to practical clinical applications. In this study, a novel postprocessing method with an efficient multi-slice acquisition scheme, called T2 spectrum analysis using a weighted regularized non-negative least squares algorithm and nonlocal mean filter (T2SPARC), is presented to overcome these obstacles and achieve a shorter acquisition time, higher image quality, and large volume coverage. In vivo results from healthy volunteers and a patient with LE showed that the T2SPARC method can generate robust and high-quality myelin water fraction maps of 10 slices within 11 min. This method also yields some useful byproducts such as intra- and extracellular water fraction and long T2 tissue water fraction maps, which can quantify lesions in different brain diseases.

  1. 多层螺旋CT灌注成像在肾脏肿瘤诊断中的应用价值%Application of multi-slice CT perfusion imaging in diagnosis of renal tumors

    Institute of Scientific and Technical Information of China (English)

    王雪莉; 胡柯军; 激扬

    2012-01-01

    Objective To investigate the diagnostic value of CT perfusion parameters for tumors of kidney. Methods Forty-two cases of renal cell carcinoma and 15 cases of renal tumors, which had integrated clinical information and pathological data, were enrolled. CT perfusion scanning ran at the maximum slice of tumor after plain scanning in all cases. The post-processing software was used to detect the blood flow( BF ),blood volume( BV ),mean transit time( MTT ) and permeability surface( PS ). Results The mean values of BF, BV,PS in renal cell carcinoma were significantly higher than those in benign tumors of kidney and contralateral kidney( P <0. 001 ), however,no statistical difference was found in MTT( P >0. 05 ). The mean values of BF,BV,PS in benign tumor of kidney were significantly lower than those of normal contralateral kidney( P <0. 001 ) ,but there was no statistical difference in MTT( P > 0. 05 ). Conclusion CT perfusion can reflect the morphological characteristics of tumors of kidney. CT Perfusion may be used to evaluate the benign or malignat tumors of kidney.%目的 探讨多层螺旋CT灌注成像对肾脏良恶性肿瘤的诊断价值.方法 本研究共包括42例肾细胞癌及15例肾脏良性肿瘤,均有完整的临床和病理资料.对所有病例先行常规肾脏CT平扫,然后对选定层面进行CT灌注扫描.通过后处理软件分别测量其灌注参数血流量(blood flow,BF)、血容量(blood volume,BV)、平均通过时间(mean transit time,MTT)和表面通透性(permeability surface,PS)值,并进行分析.结果 肾细胞癌组灌注参数BF、BV、PS平均值均明显高于肾脏良性肿瘤及对侧正常肾脏髓质,差异具有统计学意义(P0.05).肾脏良性肿瘤组灌注参数BF、BV、PS平均值均明显低于对侧正常肾脏髓质,差异具有统计学意义(P0.05).结论 CT灌注成像可以较好地反映肾脏肿瘤的血流动力学情况,有助于术前判断肿瘤的良恶性.

  2. 多排螺旋CT在快速扩弓器联合前方牵引矫治替牙期骨性反的应用效果%Application Effect of Multi-slice Spiral CT in Orthodontic Treatment of Skeletal Crossbite during Mixed Dentition by Rapid Maxillary Expansion Device Combined with Anterior Traction

    Institute of Scientific and Technical Information of China (English)

    李洪; 朱光恒; 黄文英

    2016-01-01

    目的:探讨多排螺旋CT在快速扩弓器联合前方牵引矫治替牙期骨性反的应用效果。方法:36例儿童替牙期骨性安氏Ⅲ类错患儿均接受快速扩弓器联合前方牵引矫治治疗,均同时接受拍摄X线片及MSCT片,测量上下颌骨各项参数。结果:X线片与MSCT的SNA角、SNB角、ANB角、U1-NA角、颌凸角、U1-NA距、ANS-Ptm距、L1-MP角及U1-SN角比较,差异均有统计学意义(P<0.05)。X线片各角的CV值均高于MSCT,差异均有统计学意义(P<0.05)。结论:多排螺旋CT在替牙期骨性反儿童快速扩弓器联合前方牵引矫治中上颌骨相关指标测量的精确度更高,离散程度小,重复测量结果好,通过较准确的测量数据分析来探讨快速扩弓器联合前方牵引矫治替牙期骨性反诱导上颌骨生长量的变化,对该技术作出更为准确的疗效评价并指导临床治疗等方面具有较高的应用价值。%Objective:To investigate the application effect of multi-slice spiral CT in orthodontic treatment of skeletal crossbite during mixed dentition by rapid maxillary expansion device combined with anterior traction. Method:36 children with mixed dentition skeletal class III malocclusion were treated with rapid palatal expansion and protraction treatment,were also being filmed X-ray and MSCT sheet,measuring the parameters of the upper and lower jaw.Result:X-ray and MSCT SNA angle,SNB angle,ANB angle,U1-NA angle,angle of convexity, U1-NA distance,ANS-Ptm distance,L1-MP angle and U1-SN angle of comparison,the differences were statistically significant(P<0.05).X-ray of the CV were higher than MSCT,the differences were statistically significant(P<0.05).Conclusion:The accuracy of multi slice spiral CT measurement of related indexes in skeletal malocclusion in mixed dentition children rapid palatal expansion combined with maxillary protraction in the higher dispersion degree of small, repeated measurement results, through the

  3. Approximations of noise covariance in multi-slice helical CT scans: impact on lung nodule size estimation.

    Science.gov (United States)

    Zeng, Rongping; Petrick, Nicholas; Gavrielides, Marios A; Myers, Kyle J

    2011-10-07

    Multi-slice computed tomography (MSCT) scanners have become popular volumetric imaging tools. Deterministic and random properties of the resulting CT scans have been studied in the literature. Due to the large number of voxels in the three-dimensional (3D) volumetric dataset, full characterization of the noise covariance in MSCT scans is difficult to tackle. However, as usage of such datasets for quantitative disease diagnosis grows, so does the importance of understanding the noise properties because of their effect on the accuracy of the clinical outcome. The goal of this work is to study noise covariance in the helical MSCT volumetric dataset. We explore possible approximations to the noise covariance matrix with reduced degrees of freedom, including voxel-based variance, one-dimensional (1D) correlation, two-dimensional (2D) in-plane correlation and the noise power spectrum (NPS). We further examine the effect of various noise covariance models on the accuracy of a prewhitening matched filter nodule size estimation strategy. Our simulation results suggest that the 1D longitudinal, 2D in-plane and NPS prewhitening approaches can improve the performance of nodule size estimation algorithms. When taking into account computational costs in determining noise characterizations, the NPS model may be the most efficient approximation to the MSCT noise covariance matrix.

  4. Segmentation algorithm of colon based on multi-slice CT colonography

    Science.gov (United States)

    Hu, Yizhong; Ahamed, Mohammed Shabbir; Takahashi, Eiji; Suzuki, Hidenobu; Kawata, Yoshiki; Niki, Noboru; Suzuki, Masahiro; Iinuma, Gen; Moriyama, Noriyuki

    2012-02-01

    CT colonography is a radiology test that looks at people's large intestines(colon). CT colonography can screen many options of colon cancer. This test is used to detect polyps or cancers of the colon. CT colonography is safe and reliable. It can be used if people are too sick to undergo other forms of colon cancer screening. In our research, we proposed a method for automatic segmentation of the colon from abdominal computed Tomography (CT) images. Our multistage detection method extracted colon and spited colon into different parts according to the colon anatomy information. We found that among the five segmented parts of the colon, sigmoid (20%) and rectum (50%) are more sensitive toward polyps and masses than the other three parts. Our research focused on detecting the colon by the individual diagnosis of sigmoid and rectum. We think it would make the rapid and easy diagnosis of colon in its earlier stage and help doctors for analysis of correct position of each part and detect the colon rectal cancer much easier.

  5. 多层螺旋CT小肠造影增强扫描的临床应用研究%The Clinical Applicative Study of Multi-Slice Spiral CT Enterography with Enhancement

    Institute of Scientific and Technical Information of China (English)

    专庆春; 吕永革; 莫金潮; 郑锐标; 吴冬; 梁焕莲; 赵志清; 许朝璇; 王建华

    2009-01-01

    目的 分析口服大剂量2.5%等渗甘露醇在多层螺旋CT小肠造影(multislice CT Enterography,MSCTE)增强扫描中的表现.方法 选取30例正常体检者,扫描前30min内分3次口服浓度2.5%的甘露醇2000 ml,并肌内注射20 mg山莨菪碱(654-2).然后静脉高压注入优维显100 ml后行螺旋CT增强扫描,通过获取多期(20、40、60、120 s)横断面及多平面重建(multiplanar reformation,MPR)图像,分别测量小肠各段(十二指肠、空肠、回肠)肠壁与肠腔的CT值以及小肠系膜CT值,进行对比分析.结果 小肠充盈均匀,肠腔与肠壁密度对比度好.同一期相中,小肠各段CT值无明显差异(P>0.05);小肠系膜CT值在各期相中无明显差异(P>0.05);小肠肠壁CT值在60s接近峰值,肠腔密度与肠壁密度对比度最佳.结论 口服大剂量等渗甘露醇在MSCTE增强扫描中能较好地显示肠壁细微结构及较好地反映肠壁密度,于静脉早期(60S)显示肠壁增强效果最好.

  6. Evaluation of spinal cord vessels using multi-slice CT angiography

    Institute of Scientific and Technical Information of China (English)

    陈爽; 钱建国; 冯晓源

    2004-01-01

    @@ Compared with the large number of head and neck vascular studies, computer tomography (CT) angiography of spinal vascular lesions has received relatively little attention. Several series and a few isolated cases of spinal vascular malformations demonstrated with magnetic resonance (MR) angiography have been reported.1-3 Selective digital subtraction angiography (DSA) is gold standard for diagnosis of spinal vascular lesions.4 However, it is invasive, time consuming, expensive, and dependent on the skills of the operator. Based on the DSA appearance and the surgical findings, spinal vascular malformations are generally, although not universally, classified as intradural (intramedullary and/or extramedullary) arteriovenous malformation (AVM) or arteriovenous fistula (AVF), and dural AVF. Recommended treatments of dural AVF consist of surgical obliteration and/or embolization.5-8

  7. Investigation on the optical scan condition for imaging of multi-slice spiral CT liver perfusion in rats

    Institute of Scientific and Technical Information of China (English)

    BAI Rong-jie; WANG Jin-e; JIANG Hui-jie; HAO Xue-jia; DONG Xu-peng; HUANG Ya-hua; WEI Lai

    2013-01-01

    Background Multi-slice CT liver perfusion has been widely used in experimental studies of hemodynamic changes in liver lesions,and is usually performed as an adjunct to a conventional CT examination because of its high temporal and spatial resolution,simple protocol,good reproducibility,and ability to measure hemodynamic changes of liver tissues at the capillary level.Experimental rat models,especially those of induced liver cancer,are often used in studies of hemodynamic changes in liver cancer.Carcinogenesis in rats has a similar pathological progression and characteristics resembling those in human liver cancer; as a result,rat models are often used as ideal animal models in the study of human liver cancer.However,liver perfusion imaging in rats is difficult to perform,because rats' livers are so small that different concentrations,flow rates,and dose of contrast agents during the CT perfusion scanning can influence the quality of liver perfusion images in rats.The purpose of this study,therefore,was to investigate the optimal scan protocol for the imaging of hepatic perfusion using a deconvolution mathematical method in rats by comparing the results of rats in different injection conditions of the contrast agent,including concentration,rate and time.Methods Plain CT scan conditions in eighty 2-month-old male Wistar rats were 5.0 mm slice thickness,5.0 mm interval,1.0 pitch,120 kV tube voltage,60 mA tube current,512×512 matrix,and FOV 9.6 cm.Perfusion scanning was carried out with different concentrations of diatrizoate (19%,38%,57%,and 76%),different injection rates (0.3 and 0.5 mi/s),and different injection times (1,2-3,4-5,and 6 seconds).The above conditions were randomly matched and adjusted to determine the best perfusion scan protocol.Thrae-phase contrast-enhanced scanning was performed after CT perfusion.Histological examination of the liver tissues with hematoxylin and eosin stains was done after CT scanning.Results When the concentration of the

  8. Diagnostic Value of Multi-slice CT for Thoracic Trauma%多排螺旋CT在胸部外伤诊断中的价值分析

    Institute of Scientific and Technical Information of China (English)

    王兵萍; 吴涛; 朱海峰; 贾亚男

    2016-01-01

    目的:探讨多排螺旋CT在胸部外伤中的应用价值。方法回顾性分析200例胸部外伤患者的常规X线平片和胸部CT(包括肋骨三维重建)图像,对两种检查方法发现的肋骨骨折、肺挫裂伤、气胸、胸腔积液、软组织肿等征象进行统计学分析。结果两种检查方法在肋骨骨折、肺挫裂伤、气胸、胸腔积液、软组织肿等方面均有显著性差异。结论多排螺旋CT能够对胸部外伤患者做出更加精准的伤情诊断,与X线平片相比有更高的应用价值。%Objective To discuss the clinical application of multi-slice CT in the thoracic trauma.Methods Retrospective analysis of 200 cases of thoracic trauma patients with conventional X-ray plain film, chest CT (includ ribs three-dimensional reconstruction image). Found two inspection methods for affected side thoracic bone fractures, pulmonary contusion, pneumothorax, hydrothorax, soft tissue swelling of signs for statistics and analysis.Result Two methods of checking in affected side fractured ribs, pulmonary contusion, pneumothorax, hydrothorax, soft tissue swelling, etc ,have significant difference.Conclusion MSCT can make more accurate judgment injury in patients with thoracic trauma, compared with X-ray plain film has a higher application value.

  9. MSCT多平面重组结合分型在十二指肠乳头旁憩室综合征的临床应用%Clinical application of multi-slice CT and multi-planar reconstruction in Lemmel’ s syndrome combined with its types

    Institute of Scientific and Technical Information of China (English)

    阚宏; 邓克学; 张朝强; 马友章; 田娜

    2014-01-01

    Objective To investigate the clinical application value of multi-slice CT (MSCT) and multi-planar reconstruction ( MPR) in Lemmel’ s syndrome combined with its types. Methods MSCT and MPR manifestations of 32 patients who were diagnosed as Lem-mel’ s syndrome by clinicians were retrospectively analysed. The anatomical relationship among nipples, diverticulitis and bile duct was analysed combined with endoscopic characteristic. Results There were 32 cases of Lemmel’ s syndrome, of which the central type was in 23 cases and peripheral type in 9 cases;in the 32 cases, biliary dilatation occurred in 30 cases, bile duct stones in 13 cases, acute and chronic cholecystitis in 8 cases, gallstones in 7 cases, gallbladder polyps in 2 cases, acute pancreatitis in 2 cases, and cholangiocarcinoma in 1 case. Conclusion MSCT and MPR can effectively display the anatomical relationship among nipple, diverticulitis and bile duct, and provide the basis for the etio-logical diagnosis and treatment in periampullary diverticula with pancreaticobiliary diseases.%目的:探讨MSCT多平面重组并结合分型在十二指肠乳头旁憩室综合征的临床应用价值。方法利用MPR回顾性分析32例临床确诊为十二指肠乳头旁憩室综合征的CT征象,观察憩室与乳头及胆、胰管的解剖关系,结合内镜治疗特点进行分型。结果32例乳头旁憩室综合征中中心型23例,周围型9例。32例中合并胆总管扩张30例,胆管结石13例,急慢性胆囊炎8例,胆囊结石7例,胆囊息肉2例,急性胰腺炎2例,胆管细胞癌1例。结论 MSCT多平面重组可有效显示乳头、憩室及胆、胰管的解剖关系,为合并的胆胰疾病提供病因诊断及治疗依据。

  10. Diagnostic value of multi-slice spiral CT in sternum fracture%多层螺旋CT对胸骨骨折诊断价值

    Institute of Scientific and Technical Information of China (English)

    黎健樟; 郭冬梅

    2014-01-01

    Objective:To explore the clinical value of multi-slice spiral CT expedition in the diagnosis of sternum fracture. Methods:28 cases with sternum fracture were selected from 2011 to 2013.They were as the research objects.At the same time,the multi-slice spiral CT diagnosis data were comprehensively reviewed and analyzed.Results:28 cases in this group were confirmed by multi-slice spiral CT and multiplanar reconstruction (MPR).The diagnose accordance rate was 100%.18 cases(64.29%) were diagnosed manubrium fracture.10 cases(35.71% ) were diagnosed mesosternum fracture.5 cases(17.86% ) were combined with substernal mediastinal emphesema.12 cases(42.86%) were combined with substernal mediastinal hematoma by CT scan and MPR reestablishment.Conclusion:The multi-slice spiral CT in the diagnosis of sternum fracture has ideal and reliable diagnosis effect.It is the key for clinical diagnosis of the disease as early as possible and formulating targeted treatment schedule in the future.It suggests strengthen the popularization in clinical.%目的:探讨在胸骨骨折的诊断中应用多层螺旋CT探查的临床价值。方法:2011-2013年收治胸骨骨折患者28例,作为本次研究对象,同时与其多层螺旋CT诊断资料相结合,进行综合性回顾与分析。结果:本组28例病例均经多层螺旋 CT 检查或多平面重建(MPR)后确诊,诊断符合率100%。包括18例(64.29%)诊断为胸骨柄骨折,10例(35.71%)诊断为胸骨体骨折。其中5例(17.86%)合并胸骨后纵隔气肿,12例(42.86%)经CT扫描、MPR重建后提示合并胸骨后纵隔血肿。结论:为胸部骨折患者提供多层螺旋CT诊断,能够起到理想、可靠的诊断效果,是今后临床尽早诊断本病并制定有针对性治疗方案的关键,建议临床加强普及。

  11. A comparative study for spatial resolution and subjective image characteristics of a multi-slice CT and a cone-beam CT for dental use

    Energy Technology Data Exchange (ETDEWEB)

    Watanabe, Hiroshi, E-mail: hiro.orad@tmd.ac.jp [Oral and Maxillofacial Radiology, Division of Oral Restitution, Graduate School, Tokyo Medical and Dental University, 5-45 Yushima 1-chome, Bunkyo-ku, Tokyo 1138549 (Japan); Honda, Eiichi [Oral and Maxillofacial Radiology, Division of Oral Health Sciences, The University of Tokushima Graduate School (Japan); Tetsumura, Akemi; Kurabayashi, Tohru [Oral and Maxillofacial Radiology, Division of Oral Restitution, Graduate School, Tokyo Medical and Dental University, 5-45 Yushima 1-chome, Bunkyo-ku, Tokyo 1138549 (Japan)

    2011-03-15

    Purpose: Multi-slice CT (MSCT) and cone-beam CT (CBCT) are widely used in dental practice. This study compared the spatial resolution of these CT systems to elucidate which CT modalities should be selected for various clinical cases. Materials and methods: As MSCT and CBCT apparatuses, Somatom Sensation 64 and 3D Accuitomo instruments, respectively, were used. As an objective evaluation of spatial resolution of these CT systems, modulation transfer function (MTF) analysis was performed employing an over-sampling method. The results of MTF analysis were confirmed with a line-pair test using CATPHAN. As a subjective evaluation, a microstructure visualization ability study was performed using a Jcl:SD rat and a head CT phantom. Results: MTF analysis showed that for the in-plane direction, the z-axis ultrahigh resolution mode (zUHR) of the Sensation 64 and 3D Accuitomo instruments had higher spatial resolutions than the conventional mode (64x) of the Sensation 64, but for the longitudinal direction, the 3D Accuitomo had clearly higher spatial resolution than either mode of the Sensation 64. A line-pair test study and microstructure visualization ability studies confirmed the results for MTF analysis. However, images of the rat and the CT phantom revealed that the 3D Accuitomo demonstrated the failure to visualize the soft tissues along with aliasing and beam-hardening artifacts, which were not observed in the Sensation 64. Conclusions: This study successfully applied spatial resolution analysis using MSCT and CBCT systems in a comparative manner. These findings could help in deciding which CT modality should be selected for various clinical cases.

  12. study on the significance of application of multi - slice spiral CT(MsCT)angiography in diagnosis of aortic dissecting aneurysm%多层螺旋 CT 血管成像技术在主动脉夹层动脉瘤中的应用价值

    Institute of Scientific and Technical Information of China (English)

    张喜军; 李淳成; 吴耀军

    2015-01-01

    供立体及精确的解剖信息,故 MSCTA 可作为 AD 首选的影像学检查方法。%Objectine To explore the diagnostic performance and clinical significance of multi - slice spiral CT(MSCT)angiography and computed tomography angiography(CTA)in diagnosis of aortic dissecting aneurysm. Methods The Clinical data of 68 cases diagnosed with aor-tic dissections(AD)were retrospectively analyzed. All these patients were examined with 64 - detector CTA using intelligent tracking technique for rapid volume enhanced scanning,and primary data were processed with multiplannar reformation( MPR),curved plannar reconstruction (CRP),the maximum intensity projection(MIP),volume representation technical reconstruction(VR),CT virtual endoscopy(CTVE)and vol-ume representative technical reconstruction(VR). The true and false lumens,intimal flap and tears were analyzed. Results There were 21 cases with Stanford A type,and 47 cases with B type;the average strengthening value of AD in true lumen group(279. 00 ± 46. 55 HU)was significant-ly higher than the average strengthening value of false lumen group(260. 06 ± 49. 59 HU,t = 2. 2963,P = 2. 2963). It could be seen in 66 ca-ses(97. 06% )of first tear and 60 cases(88. 24% )of re - entry tears. In 42 cases of true lumen value which strengthening value was greater than that of false lumen,the first tear size was 12. 05 ± 6. 48 mm,which was much smaller than the size of first tear(19. 08 ± 8. 56 mm,t = 3. 8394, P = 3. 8394)in 26 cases with true lumen,in which strengthening value was almost the same to that of false lumen. The true and false lumens of 60 patients with AD were spirally contorted,another 8 cases were parallel contortion,their size was differed. Enhanced scanning of 68 patients showed mezzanine intimal flap was clearly performed,and the movement was in accordance with that of true and false lumens. Bilateral common il-iac arteries were most easily affected. The rates of breach in MPR,CPR,CTVE and VR were 92. 65% ,95

  13. Application of multi-slice CT in measurement of morphological parameters of waist muscle and its clinical significance%多排螺旋 CT 在腰部肌群形态学参数测量中的应用及其临床意义

    Institute of Scientific and Technical Information of China (English)

    付卫光; 刘硕; 丁军; 安俐莹

    2015-01-01

    -69 years old group,and 70-79 years old group were set up.The lumbar transverse psoas muscle,lumbar side muscle,erector spinae cross-sectional areas (CSA)and mean CT values were measured at different levels.Scanning equipment:Toshiba Activion 16-slice spiral CT scanners, acquisition range from the waist 1 to S1.Results ①Compared between the measurement results of the same age groups (except 70-79 years old group),the average CSA of the male at the same level waist was higher than the female (P 0.05).Compared between the same level groups of 50-59 years,60-69 years and 70-79 years,there was no significant difference (P >0.05).③Compared the CSA of man’s erector spinae muscle between 40-49 years group and 50-59 years group,there were significant differences (P 0.05).⑤The same level average density of erector spinae muscle was lowest compared with the psoas major muscle and quadratus lumborum muscle,and falling faster,the psoas major muscle was relatively higher.The same level average density of female’s erector spinae muscle was lower than man’s,specially in 70-79 years group.Conclusion Multi-slice spiral CT can be used to diagnose the lumbar degenerative conditions.

  14. Application of Multi-slice Spiral CT Angiography in Diagnosis and Preoperative Evaluation of Abdominal Aortic Aneurysm%多层螺旋CT血管成像在腹主动脉瘤诊断及术前评估中的应用价值

    Institute of Scientific and Technical Information of China (English)

    刘继峰; 郭旺明

    2015-01-01

    Objective To explore the effectiveness of application of multi-slice spiral CT angiography (CTA) in diagnosis and preoperative evaluation of abdominal aortic aneurysm. Methods Altogether 82 patients conifrmed as abdominal aortic aneurysm by surgery or digital subtraction angiography (DSA) were chosen. CTA was performed to observe abdominal aorta and its branches. Multiplanar reconstruction, maximum intensity projection and volume rendering were used to reconstruct images. Then classiifcation was made, lesion sites and involved scope were located. Results Among 82 patients with abdominal aortic aneurysm, 76 cases were detected by CTA, 82 cases were detected by DSA, the difference was signiifcant (P>0.05). With evaluation by CTA, 8 cases wereⅠtype, 7 cases wereⅡA type, 9 cases wereⅡB type, 40 cases wereⅡC type, 12 cases wereⅢtype;10 cases were proximal kidney type, 66 cases were infrarenal type. Compared with DSA results, there was no statistically signiifcant difference (P>0.05). Conclusion CTA technique which could accurately evaluate the shape, site, and size of abdominal aortic aneurysm, had a high accuracy rate in diagnosis of abdominal aortic aneurysm. CTA technique could direct the selection of treatment methods and determine the surgical indications.%目的:探讨多层螺旋CT血管成像(CTA)在腹主动脉瘤诊断及术前评估中的应用价值。方法选择经手术或数字减影血管造影(DSA)证实的82例腹主动脉瘤患者作为研究对象。采用CTA技术对患者的腹主动脉及其分支进行扫描,应用多平面重建、最大密度投影、容积成像等技术对图像进行重建,并进行分型、病灶位置和累及范围等定位。结果82例腹主动脉瘤中,CTA检出76例,与DSA检查结果相比,差异无统计学意义(P>0.05)。CTA评估Ⅰ型8例、ⅡA型7例、ⅡB型9例、ⅡC型40例、Ⅲ型12例,近肾型10例,肾下型66例,与DSA检查结果相比,

  15. 多层螺旋CT扫描及重建技术在腹股沟疝分类中的应用%Application of multi-slice spiral CT and three-dimensional reconstruction techniques in the classification of inguinal hernia

    Institute of Scientific and Technical Information of China (English)

    皇旭辉; 卢跃忠; 葛宇曦

    2013-01-01

    Objective To assess the contribution of multi-slice spiral CT and three-dimensional reconstruction techniques in the accurate diagnosis of direct and indirect inguinal hernias. Methods Fifty-four patients, who had undergone both a multi-section CT and a hernioplasty, were identied in order to evaluate the display of inguinal hernia on axial, coronary and sagittal planes and to distinguish the direct and indirect inguinal hernias. Then, we compared the classification of inguinal hernia with the result of surgery. Results Inguinal hernias were clearly demonstrable using multi-section CT and reconstructions and were accurately classified in direct and indirect inguinal hernias. On coronal CT reconstructions, the anatomy of inguinal hernias was clearly demonstrated than others and the accuracy of inguinal hernias classification was 100% , following by sagittal planes with the accuracy of 94% , the axial was poor for the identication of the inguinal hernias with the accuracy rate of 87%. Conclusion The high-resolution coronal and sagittal images available from multisection CT now permit the accurate diagnosis of groin hernias. Using simple anatomical criteria, direct and indirect inguinal hernias can be reliably distinguished.%目的 评估多层螺旋CT扫描及三维重建技术在区别腹股沟直疝及斜疝的应用.方法 收集54例同时行CT扫描及外科疝修补术的腹股沟疝病例资料,分别观察CT轴位、冠状位及矢状位对腹股沟疝的显示情况并区分腹股沟斜疝及直疝,并与手术结果对照.结果 MSCT及重建可以清晰直观地显示腹股沟疝并区分直疝及斜疝.其中冠状位对腹股沟结构显示最清楚,对腹股沟疝分类诊断正确率100%;矢状位次之,诊断正确率94%;横断位诊断正确率87%.结论 MSCT及高分辨率冠状位及矢状位重建可以精确地显示以及辨别腹股沟直疝、斜疝.

  16. 多层螺旋CT重建技术诊断齿状突骨折%Diagnostic Value of Multi-slice CT in Odontoid Process Fracture

    Institute of Scientific and Technical Information of China (English)

    赵晖; 王林森; 陈思; 潘涛; 蔡琳

    2013-01-01

      Objective To evaluate the value of reconstruction of multi-slice CT in the diagnosis of odon⁃toid process fracture. Methods CT imaging of 43 patients with odontoid process fracture were analysed,and then three-dimentional reconstruction were made. Results The patients were classified into 3 types according to the part of fracture. Type I was shown in 1 case, type II was in 28 cases and type III was in the other 14 cas⁃es. Odontoid were displaced posteriorly and anteriorly in 17 and 13 cases, and there were no displacement in 13 cases. Conclusion Three-dimentional reconstruction of multi-slice CT has great value in the diagnostic part⁃ing and treating plan of odontoid process fracture.%  目的:探讨多层螺旋CT重建技术在诊断齿状突骨折中的价值。方法:分析43例齿状突骨折患者的CT资料,以及三维重建资料。结果:根据骨折部位将齿状突骨折分为3型,I型1例,II型28例,III型14例,齿状突向前移位17例,向后移位13例,无移位13例。结论:多层螺旋CT三维重建技术对于齿状突骨折的诊断分型及治疗方案的确定有指导作用。

  17. 多层螺旋CT门静脉血管成像在胰源性门脉高压症诊断中的应用%The application of multi-slice spiral CT portography in pancreatic portal hypertension disease

    Institute of Scientific and Technical Information of China (English)

    靳勇; 林晓珠; 吴云林; 朱晖; 吴志远; 瞿晴; 徐学勤; 陈克敏

    2008-01-01

    Objective To study the application of multi-slice spiral CT(MSCT) portography in diagnonsis of pancreatic portal hypertension. Methods Forty-seven patients with lesion in body or tail of pancrease,47 normal subjects and 126 patients with portal hypertension underwent MSCT portography with LightSpeed 16 CT scanner. The inner diameter of portal system and the main collateral veins were measured in maximun intensity projection (MIP) image. The volume of liver and spleen were also measured in volume rendering (VR) image. The liver parenchyma and main portal vein enhancement in portal vein phase were also taken. The endoscopy examination was made in 57 patiens with portal hypertension. Results In 47 patiens with lesion in body or tail of pancreas , stenosis or occlusion of spleen vein were found in 38 patients(pancreatic portal hypertension in 27 patients, chronic and acute pancreatitis in 11 patients). In 38 patients with pancreatic portal hypertension, esophageal varices was found in 5 patients(13.2%), gastric fundus varix in 25 patients (65.8%), gastric body variees in 22 patients (57.9%), short-gastric vein/post-gastric vein(SGV/PGV) in 26 patients (68.4%), coronal gastric vein in 26 patients (68.4%),dilated gasto-omenta vein in 24 patients(63.2%), mesenterica varicesin 1 patient, splenic vein occlusion in 14 patients (36.8%), splenic vein stenosis in 23 patinets(63.2%). Conclusions The patients with pancreatic portal hypertension were demonstrate characteristic changes in MSCT portography. The MSCT portography is helpful in etiological diagnosis of pancreatic portal hypertension by supplying images in vessel morphology.%目的 研究多层螺旋CT门静脉血管成像在胰源性门静脉高压患者诊断中的应用.方法 应用16排多层螺旋CT门静脉血管成像,对47例临床怀疑胰腺体尾部病变的患者的门静脉系统形态改变与126例肝源性门脉高压患者和47例正常对照组进行形态学对比观察,并测量胃

  18. Validation of a novel imaging approach using multi-slice CT and cone-beam CT to follow-up on condylar remodeling after bimaxillary surgery.

    Science.gov (United States)

    Nicolielo, Laura Ferreira Pinheiro; Van Dessel, Jeroen; Shaheen, Eman; Letelier, Carolina; Codari, Marina; Politis, Constantinus; Lambrichts, Ivo; Jacobs, Reinhilde

    2017-07-14

    The main goal of this study was to introduce a novel three-dimensional procedure to objectively quantify both inner and outer condylar remodelling on preoperative multi-slice computed tomography (MSCT) and postoperative cone-beam computed tomography (CBCT) images. Second, the reliability and accuracy of this condylar volume quantification method was assessed. The mandibles of 20 patients (11 female and 9 male) who underwent bimaxillary surgery were semi-automatically extracted from MSCT/CBCT scans and rendered in 3D. The resulting condyles were spatially matched by using an anatomical landmark-based registration procedure. A standardized sphere was created around each condyle, and the condylar bone volume within this selected region of interest was automatically calculated. To investigate the reproducibility of the method, inter- and intra-observer reliability was calculated for assessments made by two experienced radiologists twice five months apart in a set of ten randomly selected patients. To test the accuracy of the bone segmentation, the inner and outer bone structures of one dry mandible, scanned according to the clinical set-up, were compared with the gold standard, micro-CT. Thirty-eight condyles showed a significant (P0.6) intra- and inter-observer reliability was observed for both MSCT and CBCT. Moreover, the bone segmentation accuracy was less than one voxel (0.4 mm) for MSCT (0.3 mm±0.2 mm) and CBCT (0.4 mm±0.3 mm), thus indicating the clinical potential of this method for objective follow-up in pathological condylar resorption.International Journal of Oral Science advance online publication, 14 July 2017; doi:10.1038/ijos.2017.22.

  19. 多层螺旋CT小肠造影在小肠梗阻诊断中的应用分析%Analysis of Multi-slice Spiral CT and Enterography in Diagnosis of Small Bowel Obstruction

    Institute of Scientific and Technical Information of China (English)

    詹志勇; 王大维; 张鹏; 倪彩红

    2016-01-01

    目的:对小肠梗阻患者应用多层螺旋CT小肠造影诊断的临床效果进行分析研究。方法选取于2014年3月~2015年11月在我院接受治疗的小肠梗阻患者122例,并随机分为对照组和实验组各61例,对分别应用单气囊小肠镜检查以及多层螺旋CT小肠造影检查的效果进行对照研究。结果实验组患者检查诊断小肠梗阻的灵敏度、特异度、阳性预测值、阴性预测值均高于对照组(86.75%、100.00%、100.00%、43.57%vs.78.52%、69.58%、87.89%、31.56%),组间差异有统计学意义(P<0.05)。结论小肠梗阻患者应用多层螺旋CT小肠造影诊断的临床效果十分满意。%Objective Clinical effect of Multi-slice spiral CT and enterography in diagnosis of smal bowel obstruction(SBO)is to be studied and analyzed. Methods Chose 122 patients with smal bowel obstruction(SBO)who were treated in hospital from March 2014 to November 2015 and separated them into control group and study group randomly with 61 patients in each group,and then compared single baloon endoscopy application effect to Multi-slice CT enterography of effect between two groups.ResultsThe sensibility and specificity rate,positive-testing rate and negative -testing rate in study group were much higher than counterparts in control group(86.75%、100.00%、100.00%、43.57%vs. 78.52%、69.58%、87.89%、31.56%). There was a differential between two groups and such a differential had statistic value according to T-Check(P<0.05).Conclusion Multi-slice CT and enterography is quite effective in diagnosis of smal bowel obstruction.

  20. 多层螺旋CT多模式重组在复杂髋臼骨折术前检查中的应用%The preoperative application of multi slice CT with three-dimensional reconstruction in complex acetabular fractures

    Institute of Scientific and Technical Information of China (English)

    陈木养; 黄伟坚; 余洪希; 王东

    2016-01-01

    Objective To evaluate the value of volume scanning method, multiplanar reconstruction (MPR), surface shaded display (SSD), and volume reconstruction (VR) techniques in the preoperative examination of complex acetabular fractures. Methods Fifty-eight cases with ancetabular fractures were all accepted CT volume scanning , and MPR were done in all cases. In addition, case-control analysis were done with conventional acetabular CT imagings. Results Coronal plane of MPR, surface shaded display (SSD) combined with VR imaging, could display the acetabular fractures clearly, in accordance with the operations, and its diagnostic accuracy was significantly higher than conventional CT scan. The two sets of data had significances difference (P<0.05) in displaying fracture type, the length of the fracture lines, the shapes and direction of the fracture, the sizes of fracture pieces, the spatial location, the degree of fracture displacement and the joint dislocation classification. Conclusion Multi slice CT (MSCT) volume scanning, MPR, SSD and VR techniques have good display abilities of acetabular fractures , their performance are close to the pathological anatomy. They are considered to be the ideal imaging methods to know about the complex acetabular fractures and its microscopic structures.%目的:利用多层螺旋CT的容积扫描方法和多平面重建(MPR)、表面遮盖法(SSD)及容积再现(VR)技术,评价其在复杂性髋臼骨折术前检查中的应用价值。方法选取58例患者的损伤髋臼进行多层螺旋CT容积扫描,所得原始数据做数字化三维重组处理,并与常规髋臼CT平扫图像进行对照分析。结果 MPR冠状面、SSD重建结合VR成像,能清晰显示58例髋臼骨折情况,与手术相符,诊断正确率明显高于常规CT平扫。在显示骨折分型、骨折线的长短、形态、走向,骨折片大小、空间位置以及骨折移位程度和关节脱位分类征象方面,2组

  1. Establishing models of portal vein occlusion and evaluating value of multi-slice CT in hepatic VX2 tumor in rabbits

    Institute of Scientific and Technical Information of China (English)

    Yue-Yong Qi; Li-Guang Zou; Ping Liang; Dong Zhang

    2007-01-01

    AIM: To establish models of portal vein occlusion of hepatic VX2 tumor in rabbits and to evaluate the value of multi-slice CT.METHODS: Forty New Zealand rabbits were divided into 4 groups according to digital table: Immediate group (group A; transplantation of tumor immediately after the portal vein occlusion), 3-wk group (group B;transplantation of tumor at 3 wk after the portal vein occlusion), negative control group (group C) and positive control group (group D), 10 rabbits in each group.Hepatic VX2 tumor was transplanted with abdominal-embedding innoculation immediately after the portal vein occlusion and at 3 wk after the portal vein occlusion.Meanwhile, they were divided into negative control group (Left external branch of portal vein was occluded by sham-operation, and left exite was embedded and inoculated pseudoly) and positive control group (Transplanted tumor did not suffer from the portal vein occlusion). All rabbits were scanned with multi-slice CT.RESULTS: All 40 animals were employed in the final analysis without death. Tumor did not grow in both immediate group and 3-wk group. In 3-wk group, left endite was atrophied and growth of tumor was inhibited.The maximal diameter of tumor was significantly smaller than that in positive control group (2.55 ± 0.46 vs3.59 ± 0.37 cm, t = 5.57, P < 0.001). Incidences of metastasis in the liver and lung were lower in 3-wk group than those in positive control group (10% vs 40%, and 90% vs 100%, respectively). The expression intensities of the vascular endothelium growth factor (VEGF) in groups A, B, C and D were 0.10 ± 0.06, 0.66 ± 0.21, 0.28± 0.09 and 1.48 ± 0.32, respectively. VEGF expression level in the test group A was significantly lower than that in the negative control group C (t = 5.07; P < 0.001).In addition, VEGF expression in the test group B was significantly lower than that in the positive control group D (t = 6.38; P < 0.001). Scanning with multi-slice CT showed that displaying rate of

  2. Multi-slice spiral CT of aortocoronary grafts and internal mammary artery bypasses: Assessment of bypasses and their anastomoses; Mehrzeilen-Spiral-CT von aortokoronaren Venenbypaessen und Mammaria-interna-Bypaessen: Beurteilung der Bypaesse und ihrer Anastomosen

    Energy Technology Data Exchange (ETDEWEB)

    Froehner, S.; Wagner, M.; Schmitt, R.; Christopoulos, G.; Coblenz, G. [Inst. fuer Diagnostische und Interventionelle Radiologie, Herz- und Gefaessklinik GmbH, Bad Neustadt an der Saale (Germany); Brunn, J.; Mueller, M.; Kerber, S. [Fachbereich Kardiologie, Herz- und Gefaessklinik GmbH, Bad Neustadt an der Saale (Germany); Urbanski, P. [Klinik fuer Herzchirurgie, Herz- und Gefaessklinik GmbH, Bad Neustadt an der Saale (Germany)

    2002-07-01

    Objective: To assess aortocoronary grafts and internal mammary artery bypasses by means of EKG-triggered contrast-enhanced multi-slice spiral CT, and to evaluate the diagnostic accuracy of this new imaging modality. Material and methods: 59 patients with up to 5 aortocoronary grafts and/or internal mammary artery bypasses per patient were examined with regard to bypass morphology, the free passage, and the proximal as well as the distal anastomoses using multi-slice computed tomography. Axial source images were calculated by means of retrospective triggering at different diastolic delay times, and were postprocessed in several planes with the multiplanar volume reconstruction (MPVR) software. Results: On the pre-condition that data sets were acquired at sinus rhythm and at a heart rate lower than 65/min, aortocoronary grafts and internal mammary artery bypasses could be depicted in adequate diagnostic quality in about 80% of all cases with contrast-enhanced multi-slice spiral CT. Both, the free passage of the bypasses as well as the morphology of the proximal anastomoses were sufficiently assessed with multiplanar volume reconstruction (MPVR), whereas the distal anastomoses couldn't be depicted sufficiently in 20% of all cases. Conclusion: As a non-invasive method, contrast-enhanced and ECG-triggered multi-slice spiral computed tomography has gained diagnostic potential for the accurate visualization of aortocoronary grafts and the internal mammary artery bypasses. (orig.) [German] Ziel: Die vorliegende Arbeit stellt die Moeglichkeiten der kontrastmittelverstaerkten, EKG-getriggerten Mehrzeilen-Computertomographie in der Beurteilung von aortokoronaren Venenbypaessen und Mammaria-interna-Bypaessen dar. Material und Methode: Bei 59 Patienten mit 1 bis 5 aortokoronaren Venen-Bypaessen bzw. Mammaria-interna-Bypaessen wurden deren Morphologie, Durchgaengigkeit, die proximalen Anastomosen und die distalen Insertionsstellen mittels Mehrzeilen-Spiral-CT untersucht

  3. 多层螺旋CT对颌骨放射性骨坏死的诊断价值%DIAGNOSTIC VALUE OF MULTI-SLICE SPIRAL CT FOR OSTERORADIONECROSIS OF JAW

    Institute of Scientific and Technical Information of China (English)

    林颖; 曹代荣; 游瑞雄; 江飞; 郑义浩

    2014-01-01

    Objective:To investigate the diagnostic value of multi-slice spiral CT for osteoradionecrosis of jaws (ORNJ). Methods:The CT ifndings of 27 cases ORNJ that were conifrmed by surgery and pathology were retrospectively analyzed. Results: The main CT ifndings of ORNJ were limited bone destruction and sequestration.Conclusions:Multi-slice spiral CT can clearly display location and appearance of lesions, sequestration, periosteal reaction and soft tissue mass formation. So multi-slice spiral CT has important value for diagnosis and differential diagnosis of ORNJ.%目的::探讨多层螺旋CT对颌骨放射性骨坏死(ORNJ)的诊断价值。方法:回顾性分析27例经手术、病理证实为ORNJ的CT表现。结果:ORNJ在多层螺旋CT上主要表现为局限性骨质破坏和死骨形成。结论:多层螺旋CT能清楚的显示ORNJ病灶的位置、形态、病灶内的死骨形成、有无骨膜反应及软组织肿块形成等,对ORNJ的诊断及鉴别诊断有重要的价值。

  4. A comparative evaluation of Cone Beam Computed Tomography (CBCT) and Multi-Slice CT (MSCT). Part II: On 3D model accuracy

    Energy Technology Data Exchange (ETDEWEB)

    Liang Xin, E-mail: Xin.Liang@med.kuleuven.b [Oral Imaging Centre, School of Dentistry, Oral Pathology and Maxillofacial Surgery, Faculty of Medicine, Catholic University of Leuven (Belgium); College of Stomatology, Dalian Medical University (China); Lambrichts, Ivo, E-mail: Ivo.Lambrichts@uhasselt.b [Department of Basic Medical Sciences, Histology and Electron Microscopy, Faculty of Medicine, University of Hasselt, Diepenbeek (Belgium); Sun Yi, E-mail: Sunyihello@hotmail.co [Oral Imaging Centre, School of Dentistry, Oral Pathology and Maxillofacial Surgery, Faculty of Medicine, Catholic University of Leuven (Belgium); Denis, Kathleen, E-mail: kathleen.denis@groept.b [Department of Industrial Sciences and Techology-Engineering (IWT), XIOS Hogeschool Limburg, Hasselt (Belgium); Hassan, Bassam, E-mail: b.hassan@acta.n [Department of Oral Radiology, Academic Centre for Dentistry Amsterdam (ACTA), Amsterdam (Netherlands); Li Limin, E-mail: Limin.Li@uz.kuleuven.b [Department of Paediatric Dentistry and Special Dental Care, School of Dentistry, Oral Pathology and Maxillofacial Surgery, Faculty of Medicine, Catholic University of Leuven (Belgium); Pauwels, Ruben, E-mail: Ruben.Pauwels@med.kuleuven.b [Oral Imaging Centre, School of Dentistry, Oral Pathology and Maxillofacial Surgery, Faculty of Medicine, Catholic University of Leuven (Belgium); Jacobs, Reinhilde, E-mail: Reinhilde.Jacobs@uz.kuleuven.b [Oral Imaging Centre, School of Dentistry, Oral Pathology and Maxillofacial Surgery, Faculty of Medicine, Catholic University of Leuven (Belgium)

    2010-08-15

    Aim: The study aim was to compare the geometric accuracy of three-dimensional (3D) surface model reconstructions between five Cone Beam Computed Tomography (CBCT) scanners and one Multi-Slice CT (MSCT) system. Materials and methods: A dry human mandible was scanned with five CBCT systems (NewTom 3G, Accuitomo 3D, i-CAT, Galileos, Scanora 3D) and one MSCT scanner (Somatom Sensation 16). A 3D surface bone model was created from the six systems. The reference (gold standard) 3D model was obtained with a high resolution laser surface scanner. The 3D models from the five systems were compared with the gold standard using a point-based rigid registration algorithm. Results: The mean deviation from the gold standard for MSCT was 0.137 mm and for CBCT were 0.282, 0.225, 0.165, 0.386 and 0.206 mm for the i-CAT, Accuitomo, NewTom, Scanora and Galileos, respectively. Conclusion: The results show that the accuracy of CBCT 3D surface model reconstructions is somewhat lower but acceptable comparing to MSCT from the gold standard.

  5. Analysis of multi-slice spiral CT images in patients with esophageal cancer after surgery or radiotherapy%食管癌患者术后或放疗后多排螺旋 CT 影像分析

    Institute of Scientific and Technical Information of China (English)

    王锋

    2016-01-01

    Objective To explore the application value of multi-detector row spiral CT after the operation or radiotherapy in patients with esophageal carcinoma .Methods From August 2014 to March 2015,23 patients with esophageal cancer treated in our hospital received the examination of multi-detector row spiral CT after the operation or radiotherapy .Results After operation,CT re-sults showed that there were 4 cases with postoperative lymph node metastasis ,2 with lung metastasis and 3 with bone metastases ,2 with pericardial effusion ,1 with pleural effusion ,1 with esophageal mediastinum fistula and 1 with anastomotic recurrence .CT results also showed that after radiotherapy there were 12 with lymph node metastasis ,2 with liver metastasis ,3 with lung metastasis ,1 with radioac-tive pneumonia and 2 with pleural effusion .Conclusion The multi-slice helical CT can display a number of clinical manifestations such as complications ,recurrence and metastasis after operation and radiotherapy .It has an important clinical value .%目的:探讨多排螺旋CT在食管癌患者术后或放疗中的应用价值。方法2014年8月至2015年3月我院收治的23例食管癌患者,术后或放疗后均行多部位多排螺旋CT检查。结果 CT结果显示:术后患者出现淋巴结转移4例,肺部转移2例,骨转移3例,心包积液2例,胸腔积液1例,食管纵膈瘘1例,吻合口复发1例;而放疗后患者出现淋巴结转移12例,肝脏转移2例,肺部转移3例,放射性肺炎1例,胸腔积液2例。结论多排螺旋CT可显示出食管癌患者术后或放疗后的并发症、复发及转移等临床表现,具有重要的临床应用价值。

  6. Effect of Multi Slice Spiral CT in the Diagnosis of Gastrointestinal Tract Perforation%多层螺旋CT在胃肠道穿孔诊断中的应用效果

    Institute of Scientific and Technical Information of China (English)

    高运英

    2014-01-01

    Objective To explore the clinical application of multislice spiral CT in the diagnosis of gastrointestinal tract perforation in effect. Methods In our hospital diagnosed as gastrointestinal perforation in 42 cases of the disease, to get the related information of their multi slice spiral CT scanning. Research on MSCT the image data, analyze the internal various features of abdominal and free gas ratio. Results In all 42 patients, diagnosed by MSCT were 39 cases, accounting for about 92.86%. In addition to, accurately determine the position of the 25 cases, about 59.52%. Also observe gastrointestinal tumor, abscess, and effusion lesions. Conclusion The clinical application of multi slice spiral CT in the diagnosis of gastrointestinal tract perforation has very good effect, can improve the diagnosis rate and hole position accuracy. This method is suitable for use in clinical practice.%目的:探讨多层螺旋CT在胃肠道穿孔中的诊断效果。方法回顾性分析经病理确诊为胃肠穿孔患者的多层螺旋CT扫描的相关资料共42例,探究MSCT所得影像资料,分析腹腔内部各种特征和游离气体比例等。结果在所有42例病患中,经MSCT确诊的有39例,约占92.86%。此外,准确确定穿孔位置的有25例,约占59.52%。同时观察到胃肠道有肿块、脓肿、积液等病变。结论多层螺旋CT应用于胃肠道穿孔诊断方面有很好的效果,有利于提高确诊率和孔道位置准确率,此方法适合在临床上推广使用。

  7. Multi-slice CT for detection of patent foramen ovale%MSCT诊断卵圆孔未闭

    Institute of Scientific and Technical Information of China (English)

    毛新波; 陈涛

    2012-01-01

    目的:探讨心电门控MSCT心脏成像检测卵圆孔未闭的可行性.方法:对124例患者行MSCT心脏成像,根据房间隔隧道样外观和心房间左向右分流来诊断PFO.结果:在MSCT上共发现29例PFO(23.4%).在22例同时行经胸超声(TTE)和CT的患者中,以TTE作为金标准,根据房间隔内通道和分流,CT诊断PFO的敏感性、特异性分别为66.6%和93.7%,阳性预测值为80.0%,阴性预测值为88.2%.结论:MSCT能可靠地检测PFO.%Objective: the purpose was to show the feasibility of ECG-gated MSCT cardiac angiography for the detection of patent foramen ovale. Methods: MSCT cardiac angiography was performed on 124 patients. CT criteria for the diagnosis of PFO were according to channel-like appearance of the interatrial septum and interatrial shunting from left to right. Results: Twenty-nine(23. 4%)were found to have a PFO by CT. Of the 22 patients who underwent both TTE and CT,using TTE as gold criteria, the sensitivity,specificity,positive predictive value and negative predictive value of diagnose PFO by MSCT were 83. 3%, 88. 8% ,71. 4% and 94.1% .respectively. Conclusion: MSCT cardiac angiography can be used to reliably detect PFO.

  8. Value of multi-slice helical CT for diagnosing colonic diverticulitis%多层螺旋CT在结肠憩室炎诊断中的价值

    Institute of Scientific and Technical Information of China (English)

    万荣超; 邓德茂; 袁文昭; 陈文福; 李敏; 廖海; 陈加军

    2014-01-01

    Objective To determine the multi-slice spiral computed tomography(MSCT)features of colonic diverticulitis. Methods The clinical information and MSCT of 11 patients with pathologically confirmed colonic diverticulitis were retrospectively analyzed.Results CT showed colonic diverticula with surrounding fat stranding(10)and fecalith in the diverticula(7),pericolonic fat stranding and pneumoperitoneum(1),colon wall thickening(9),bowel perforation(5)with pneumoperitoneum(3)and hematoma(1). Conclusion MSCT displays clearly the pathological changes and complications of colonic diverticulitis.%目的:分析结肠憩室炎MSCT表现,以提高对该病的认识和诊断水平。方法回顾性分析11例经结肠镜检或手术病理证实结肠憩室炎病例的临床及MSCT资料,并结合文献复习。所有病例均作腹盆部CT平扫检查,其中2例加作CT增强检查,总结结肠憩室炎的MSCT表现特征。结果 CT表现为结肠肠壁囊袋状突出并周围脂肪密度增高10例,其中憩室内粪石7例,仅表现为肠壁周围脂肪密度增高及气腹征者1例,结肠肠壁增厚9例,憩室炎穿孔5例,其中气腹3例,合并出血1例。结论 MSCT能较好的显示结肠憩室炎病变及其并发症,对结肠憩室炎有较高的诊断价值。

  9. Evaluation of multi-slice spiral CT in diagnosis of abdominal cocoon%多层螺旋CT在诊断腹茧症中的价值

    Institute of Scientific and Technical Information of China (English)

    何剑; 沈健; 周玮; 祝跃明

    2015-01-01

    目的:探讨多层螺旋 CT(MSCT)在诊断腹茧症中的价值。方法回顾性分析6例经手术病理证实为腹茧症患者的MSCT 资料,采集数据在工作站用平面重建(MPR)、最大密度投影(MIP)及容积重建(VR)技术进行三维重建,观察病灶的空间解剖关系。结果6例均可见局部小肠及其系膜结构聚集成团,肠管折叠盘绕排列呈“手风琴”状或“香蕉”状。肠袢周围可见低密度的纤细纤维包膜,包膜厚薄不一,增强后纤维包膜强化轻度。受累小肠系膜血管走行异常,呈现肠系膜及其血管聚集、牵拉。结论MSCT 可以提供丰富的诊断信息,是腹茧症的首选检查方法。%Objective To investigate the value of multi-slice CT in diagnosis of abdominal cocoon.Methods CT findings of six cases with pathologically proved abdominal cocoon were collected and analyzed retrospectively.The three-dimensional imagines were obtained including multi-planar reconstruction(MPR),maximum intensity projection(MIP)and volume rendering(VR)at workstation,the rela-tionships between the lesions and surrounding structure were observed.Results A group of local small intestine were seen gathered in all six cases,the coiled intestine arranged in"accordion"shape or"banana"shape.The fibrous capsule were seen around them with different thickness,which were low density and slightly enhancement.Mesenteric arteries showed abnormal changes,showing ten-sion,aggregation.Conclusion MSCT can provide a wealth of diagnostic information and is the best method of examination abdomi-nal cocoon.

  10. 多排螺旋CT在胃肠道肿瘤及并发症的诊断价值%Multi-slice Spiral CT in the Diagnosis of Gastrointestinal Tumor and Complications

    Institute of Scientific and Technical Information of China (English)

    高云; 郑晓林; 尹昌媛

    2013-01-01

    目的 探讨多排螺旋CT在胃肠道肿瘤及并发症的诊断价值. 材料和方法 回顾性分析43例胃肠道肿瘤的多排螺旋CT表现,观察分析胃肠道肿瘤的直接CT征象及并发症征象.结果 CT可以直接发现胃肠道肿块的32例,肠管壁增厚11例,肠梗阻18例,肠套叠3例,肠扭转5例,消化道出血1例,肠系膜血管增粗26,肠系膜淋巴结肿大15例,肝脏转移7例,大网膜转移3例.结论 多排螺旋CT在消化道肿瘤的诊断方面有较高的临床实用价值,值得推广应用.%Objective To investigate diagnostic value of multi-slice spiral CT on the gastrointestinal tumor and complications.Materials and methods Multi-slice spiral CT performance of 43 patients with gastrointestinal tumors were retrospectively analyzed,to observe and analyze direct CT findings and complications CT findings of gastrointestinal tumors.Results 32 cases of the gastrointestinal masses could be directly found by multislice spiral CT; 11 cases of bowel wall thickening; 27 cases of intestinal obstruction; 3 cases of intussusception; 5 cases of volvulus; 1 case of gastrointestinal bleeding; 26 cases of mesenteric vascular thickening; 15 cases of mesenteric lymph nodes; 7 cases of liver metastases; 3 cases of omentum metastasis.Conclusion Multi-slice spiral CT in the diagnosis of gastrointestinal tumors had higher clinical value,should be widely applied.

  11. The Clinical Value of Multi-slice CT Perfusion in the Differentiation of Lung Lesions%多层CT灌注技术在鉴别肺占位病变的临床价值

    Institute of Scientific and Technical Information of China (English)

    何建平; 白毓

    2015-01-01

    目的:探讨多层CT灌注技术在鉴别肺占位病变中的应用价值。方法前瞻性分析我院自2013年2月-2015年2月收治的92例肺部占位病变患者,其中肺癌58例,病灶直径2-7cm,34例为良性,其中肺结核14例,肺脓肿6例,炎性假瘤2例,非特异性炎症6例,错构瘤4例,曲菌球2例,病灶直径2-5cm,所有病例均行多层CT灌注扫描,图像传输至工作站,应用肿瘤软件包分析,记录病变BV(血容积)、BF(血流量)、PS(表面渗透性)、MTT(平均通过时间),分析多层CT灌注成像在鉴别肺肿瘤病变中的应用价值。结果本组92例肺部占位患者,恶性病变患者灌注参数BF、BV、MTT、PS参数均较良性组高,两组间BV、MTT及PS参数差异有统计学意义(P<0.05),以BV值≥6mg/100g作为恶性病变阈值,则多层CT灌注成像诊断良性组符合率为64.71%,恶性组符合率则达100.00%。若以PS值≥30ml/min·100g作为恶性病变阈值,34例良性肺病变中,30例确诊,符合率为88.24%,4例误诊(肺结核2例,肺脓肿2例),58例恶性病变中,50例确诊,8例误诊,符合率为86.21%。结论恶性肺肿瘤CT灌注参数BV、PS值均高于良性组。多层螺旋CT灌注成像检查,可反映不同性质肺肿瘤病变微血管特征,有利于良恶性肿瘤的鉴别。%Objective To investigate the application value of multi-slice CT perfusion in the differentiation of lung lesions.Methods A total of 92 cases lung lesions patients which admitted into the hospital during February 2013 to February 2015 were prospectively analyzed. Among the objects, 58 cases were lung cancer with the diameter of 2-7cm,34 cases were benign lesions, including pulmonary tuberculosis (14 cases), lung abscess (6 cases), inflammatory pseudotumor in (2 cases), nonspecific inflammation(6 cases), hamartoma in (4 cases), and Aspergillus in (2 cases). The diameters of the lesions were 2 to 5cm. All cases underwent multi-slice

  12. 腮腺腺淋巴瘤的多排螺旋CT表现特点%Characteristics of parotid gland lymphoma observed by multi-slice spiral CT

    Institute of Scientific and Technical Information of China (English)

    薛晶; 邹新农; 崔兴宇

    2012-01-01

    目的:探讨腮腺腺淋巴瘤的多排螺旋CT表现特点.方法:对我院经手术病理证实的18例腮腺腺淋巴瘤患者的临床和CT图像资料进行总结分析,所有病例均行CT平扫和增强.结果:男16例,女2例;平均年龄58.7岁,在50岁以上者14例.单侧发病15例,双侧发病3例,共23个病灶;位于腮腺后下象限16个,非后下象限7个;呈类圆形17个,圆形5个,有明显分叶状1个;平均最大径为2.4 cm;境界均清晰光整;密度均匀16个,密度不均伴囊变坏死区7个,CT值为16.2~43.5 Hu.增强扫描早期病灶明显强化18个,中度强化5个,CT值上升平均值为(50.3±15.8)Hu;均匀强化16个,不均匀强化7个;延迟期病灶密度迅速降低21个,缓慢降低2个.结论:腮腺腺淋巴瘤好发于50岁以上男性,多位于腮腺后下象限,CT平扫病灶边界清楚光整,呈均匀或者不均匀稍高密度,增强扫描多明显强化,呈"快进快出"特点.%Objective To evaluate the characteristics of parotid gland lymphoma observed by multi-slice spiral CT. Methods Clinical and CT image data of 18 patients with parotid gland lymphoma which were pathologically confirmed in our hospital were analyzed, all patients received CT scan and enhanced scan. Results Among the 18 patients, 16 were males, 2 were females; the average age was 58.7 years, and 14 patients over the age of 50. Fifteen patients with unilateral lymphoma, and 3 patients with bilateral lymphoma, all accounted to a total of 23 lesions. Among all the 23 lesions, 16 located in the following quadrant, 7 located in the following non-inferior quadrant; 17 were similarly round, 5 were round, and 1 was obviously lobulated; the average maximum diameter was 2.4 cm and the boundaries were clear finishing. The density of 16 lesions were uniform, 7 lesions were uneven with cystic necrosis, and the CT value was 16.2 ~ 43.5 Hu. Enhanced scan showed that 18 lesions were significantly enhanced early, 5 lesions were moderately enhanced, and the

  13. Diagnosis of acute mesenteric ischemia with multi-slice spiral CT%急性肠系膜缺血的MSCT诊断

    Institute of Scientific and Technical Information of China (English)

    贾乾君; 梁长虹; 张水兴; 刘再毅

    2011-01-01

    目的:探讨MSCT对急性肠系膜缺血的诊断价值.方法:回顾性分析经手术或介入治疗证实的36例急性肠系膜缺血患者的CT表现.所有患者均行CT检查,包括平扫、增强扫描动脉期、增强扫描门脉期并进行血管重建.后处理采用容积显示技术(VRT)、多平面重组(MPR)和薄层最大密度投影(MIP)进行动脉和门脉成像.结果:肠系膜上动脉栓塞5例,肠系膜上动脉狭窄6例,肠系膜上静脉血栓形成25例.CT直接征象为血管内充盈缺损(30例)或狭窄(6例).间接征象包括:肠管扩张、肠腔内积液积气(22例),肠壁增厚(14例),肠壁薄纸样改变(3例),肠壁积气(3例).肠系膜脂肪水肿及渗出(4例).结论:MSCT与其三维重组技术相结合是诊断急性肠系膜缺血的一种有效且无创的影像检查方法,可以明确阻塞动脉的部位及范围,对手术有较高的指导价值.%Objective : To study the clinical value of multi-slice spiral CT(MSCT) in the diagnosis of acute mesenteric ischemia. Methods:The CT features of 36 patients with surgery/interventional therapy proved acute mesenteric ischemia were reviewed retrospectively. All patients underwent MSCT scanning,including plain scan, arterial phase and portal vein phase scanning after contrast administration. Post-processing techniques including volume rendering, multi-planar reformation and thin-section maximum intensity projection were performed to assess the mesenteric artery and vein, as well as the portal vein. Results:There were 5 cases of superior mesenteric artery embolism,6 cases of superior mesenteric artery stenosis and 25 cases of superior mesenteric vein thrombosis. The direct CT signs were filling defect (n=30) or stenosis (n=6)of mesenteric vessels. The indirect CT signs includcd: dilatation of bowel loops with air-fluid levels (n=22) , bowel wall thickening ( n= 14) , paper-like thin wall sign ( n= 3) , pneumatosis of bowel wall ( n= 3) , edema and exudation of mesenteric

  14. Value of multi-slice CT in patients with congenital inner ear malformation before cochlear implantation%多层螺旋CT在内耳畸形的人工耳蜗植入术前评估中的价值

    Institute of Scientific and Technical Information of China (English)

    吴琛; 熊玉伟; 周运锋

    2015-01-01

    目的:探讨多层螺旋CT在患有内耳畸形的人工耳蜗植入术前评估中的价值。方法:搜集我院因听力障碍拟行人工耳蜗植入的患者34例,所有患者均行多层螺旋CT检查。结果:34例患者中患内耳畸形的有10例共19耳,多数病耳合并多种畸形,其中耳蜗畸形8耳,前庭导水管扩大畸形8耳,前庭、半规管畸形4耳,内听道发育异常3耳。结论:多层螺旋CT扫描结合后处理技术可以更加准确地对内耳畸形做出诊断,在人工耳蜗植入术前具有重要的指导价值。%Objective:To evaluate the value of multi-slice CT in patients with congenital inner ear malformation before cochlear implantation .Methods:Multi-slice CT was performed in 34 patients with hearing impairment before cochlear implantation .Results:In 34 patients,inner ear malformation was de-tected in 10(19 ears),and more cases were complicated with multiple malformations,in which 8 cases were cochlear malformations,8 enlarged vestibular aqueduct malformation,4 vestibule and semi-circular canal malformations,and 3 internal auditory cannal malformations.Conclusion:Multi-slice CT can make accurate diagnosis of congenital inner ear malformations before cochlear implantation .

  15. 小儿消化道重复畸形的MSCT表现%Multi-slice CT characteristics of gastro-intestinal tract duplication in children

    Institute of Scientific and Technical Information of China (English)

    谢婵来; 龚英; 李国平; 帕米尔; 张大江; 王莉; 乔中伟; 缪飞

    2013-01-01

    目的:探讨MSCT对小儿消化道重复畸形的诊断价值.方法:回顾性分析27例经手术病理证实的小儿消化道重复畸形病例,分析其CT表现,包括囊肿部位、形态、密度和囊壁厚度,并分析其相关并发症.结果:27例消化道重复畸形中发生在食管2例,胃3例,胃合并食管1例,小肠19例,结肠2例.囊肿形态在CT上表现为圆形23例、管形3例、圆形-管形复合型1例.25例囊肿CT平扫为液性低密度,1例合并囊内出血呈高密度,1例囊内可见气体.囊壁厚度大于同层面肠壁者有22例,囊壁均有强化,2例囊壁可见钙化.27例囊肿中,6例出现并发症,包括囊内出血1例,囊肿破裂穿孔伴胰腺炎1例,继发肠梗阻4例.结论:低密度液性囊肿(偶见气体)、厚壁、管形或圆形-管形复合型形态是消化道重复畸形特征性的CT表现.CT对诊断消化道重复畸形合并肠旋转不良、肠闭锁等畸形和(或)伴发肠梗阻、肠扭转等病变颇具优势.%Objective:To assess the value of multi-slice CT (MSCT) in the diagnosis of gastro-intestinal tract (GI tract) duplication in children. Methods: The MSCT findings of 27 children with surgery and pathology proven GI tract duplication were retrospectively analyzed,including the location,size,density and wall thickness of duplication cyst,as well as the complications. Results:In Of these 27 cases, the duplication located at esophagus (n= 2) , storach and esophagus (n=1) , stomach (n=3) ,small intestine (n=19) and colon (n=2). The shape of duplication cyst was round (n=23) ,tubular (n= 3) and round-tubular (n=l). On plain CT,the density of duplication cyst was fluid-like with low attenuation (n=25) , but one presented as high density due to intra-cystic hemorrhage,and one with small amount of intra-cystic air. The cystic wall was thicker than the intestinal wall on the same slice (n=22) and all of the cystic wall enhanced after contrast administration. Calcification of cystic wall was

  16. Multi-slice Spiral CT Manifestation of Parotid Tumors%腮腺肿瘤的多层螺旋CT表现

    Institute of Scientific and Technical Information of China (English)

    侯学文; 张利中

    2016-01-01

    Objective To investigate the multi-slice spiral CT (MSCT) features of parotid tumors to provide clinical references. Methods Retrospective analysis was conducted on the MSCT manifestation of 23 patients whose diagnosis of parotid tumors were confirmed surgically and pathologically (including 3 cases of mucoepidermoid carcinoma, 11 cases of pleomorphic adenoma, 4 cases of adenolymphoma, 2 cases of lipoma, 2 cases of eosinophilic lymphocytes in the granuloma, 1 case of benign myoepithelial tumor). Through the CT manifestation tumor distribution, form, density, edge, cystic degeneration or necrosis, degree of enhancement, cervical lymph node enlargement of 23 cases were studied. Results Most pathological changes of the parotid gland were unilateral, of which 15 were left and 8 were right. Benign tumors usually located at the junction of the superficial lobe of parotid glands and the deep lobe of parotid glands. The shape of benign tumors was round or mass. The boundary was clear, and the density was uniform and higher than the normal parotid gland tissue. As shown by enhancing scanning, the calcification was found in the multiple adenomas and the cystic changes were found in the pleomorphic adenoma. Malignant tumors were usually located in deep lobes and were lobulated. The boundary was less clear. The density was uneven and more dense than normal parotid gland. Enhanced scan revealed inhomogeneous enhancement. Malignant parotid tumors were often accompanied by cervical lymph node enlargement. Conclusion Parotid gland tumors have certain imaging features. MSCT is helpful in the diagnosis and differential diagnosis and has important clinical diagnostic value.%目的:探讨腮腺肿瘤的多层螺旋CT表现,为临床提供参考。方法回顾性分析23例经手术病理证实的腮腺肿瘤患者(粘液表皮样癌3例,多形性腺瘤11例,腺淋巴瘤4例,脂肪瘤2例,嗜酸性淋巴细胞肉芽肿2例,肌上皮良性病变1例)的多层螺旋CT

  17. Diagnosis of traumatic hemarthrosis lipemia by multi-slice spiral CT and magnetic resonance imaging features%创伤性关节积脂血症的多排螺旋CT及磁共振成像诊断

    Institute of Scientific and Technical Information of China (English)

    沈丽荣; 姜兆候; 张立云; 刘永明

    2014-01-01

    Objective To evaluated traumatic hemarthrosis lipemia multi-slice spiral CT and magnetic resonance imaging (MRI) features and diagnostic value. Methods A retrospective analysis of multi-slice spiral CT and MRI features in 23 cases patients with traumatic hemarthrosis hyperlipidemia. All patients were examinated after injury bet-ween one hour to one week by 16-slice spiral CT or MRI, of which 19 cases of knee, hip 4 cases, all patients under-went multi-slice spiral CT, images were transmitted to a workstation for multi-planar reconstruction (MPR), shaded surface display (SSD), volume rendering (VR) and other three-dimensional restructuring, 15 cases of parallel MRI. Results Twenty three patients were joint capsule appeared fat-blood interface sign, including one case of suspected fracture CT, MRI was clear. In 23 patients, a single liquid-liquid plane 17 cases, two liquid-liquid flat 6 cases, liquid-liquid flat top were fat. Conclusion There are characteristic imaging findings of traumatic hemarthrosis lipemia examined by multi-slice spiral CT and MRI , three-dimensional multi-slice spiral CT examination and restructuring can be used as the preferred; MRI is the best imaging method in diagnostic plot lipemia traumatic knee; Plot lipemia can be used as a indirect dia-gnostic signs of intraarticular fractures.%目的:探讨创伤性关节积脂血症的多排螺旋CT及磁共振成像(MRI)影像学特点及诊断价值。方法回顾性分析23例创伤性关节积脂血症患者的多排螺旋CT及MRI影像学特征。所有患者于受伤后1 h至1周内行16排螺旋CT和(或)MRI检查,其中,膝关节19例,髋关节4例,所有患者均行多排螺旋CT检查,图像均传递到工作站进行多平面重组、表面遮盖法、容积再现等三维重建,15例并行MRI检查。结果23例患者关节囊均出现脂肪-血液界面征,其中1例CT可疑骨折,行MRI检查明确诊断。23例患者中,单液-液平面的17

  18. Diagnostic value of multi-slice spiral CT in occult fractures of proximal tibia%多层螺旋CT对胫骨近端隐匿性骨折的诊断价值

    Institute of Scientific and Technical Information of China (English)

    周俊; 陈庆; 许文渊; 姚雯雯

    2012-01-01

    目的 探讨多层螺旋CT对胫骨近端隐匿性骨折的诊断价值.方法 回顾性分析23例数字放射摄影诊断可疑胫骨近端骨折病例的16层螺旋CT的横轴位、多平面重建、容积再现、最大密度投影,观察多层螺旋CT对胫骨近端隐匿性骨折的诊断率.结果 所选病例数字放射摄影均未显示明确骨折线,16层螺旋CT诊断胫骨近端骨折17例,其中胫骨平台骨折13例、胫骨髁间棘骨折4例;排除骨折6例,阳性率达73.9%.结论 多层螺旋CT对临床怀疑胫骨近端骨折而数字放射摄影不能确诊为骨折的病例能准确地作出诊断,对治疗方案的选择及预后的估计有重要价值.%Objective To discuss the diagnostic value of multi-slice spiral CT for the occult fracture of proximal tibia. Methods 23 patients with suspected fracture of proximal tibia by digital radiography were studied, and their images of transverse, multiplanar reconstruction, and volume rendering and maximum intensity projection of 16-slice spiral CT were analyzed. The diagnostic rate for occult fracture of proximal tibia with multi-slice spiral CT was observed. Results Digital radiography showed no definite fracture signs in all patients. 16-slice spiral CT showed fractures in 17 cases, including fractures of tibia plateau in 13 cases and tibia eminence in 4 cases. The other 6 patients showed negative on 16-slice spiral CT images. Conclusion Multi-slice spiral CT can be used to diagnose definitely occult fractures of proximal tibia and plays an important role in selecting therapy project and evaluating prognosis of occult fractures.

  19. Multi-slice spiral CT three-dimensional imaging and perfusion imaging in acute brain injury of dynamic application%多层螺旋CT三维图像重建和脑灌注成像在急性颅脑损伤动态变化中应用

    Institute of Scientific and Technical Information of China (English)

    杨小秦; 柳少光; 王治民; 王学斌; 张可; 魏晓东; 张冬志

    2012-01-01

    Objective Discussion of ultrathin multilayer spiral CT 3D image reconstruction,skull and brain perfusion imaging in acute brain injury to dynamic changes in the clinical value.Methods 2009December to 2011 October were collected in our hospital in 245 patients with acute traumatic brain injury patients check information,both in the 3-6 h after injury within conventional multislice spiral CT,thin multilayer spiral CT and three-dimensional image reconstruction of skull and brain CT perfusion imaging examination,all the cases in 2 to 7 days after injury dynamic review of conventional MSCT and ultrathin multilayer spiral CT,the data were retrospectively analyzed,using the chi-squared test evaluation.Results Super thin multilayer spiral CT in cerebral contusion and laceration,intracerebral hematoma in TBI with mixed diagnosis has statistics difference is better than the conventional MSCT.CTP in acute traumatic brain injury diagnosis was superior to conventional MSCT except diffuse axonal injury.CTP in cerebral contusion and laceration,subdural hematoma and intracerebral hematoma associated with intracerebral hematoma in the diagnosis with statistical difference,better than the ultrathin multilayer spiral CT (P < 0.05).The 3D image reconstruction of skull fracture demonstrated great advantages in the treatment of skull fracture,which include cranial suture separation and basal skull fracture.Conclusion combined Super thin multilayer spiral CT 3D image reconstruction skull and brain CT perfusion imaging for acute craniocerebral injury early diagnosis and minimal injury diagnosis is superior to conventional multislice spiral CT,The rate of misdiagnosis can be decreased.which provide Reliable basis for early diagnosis and Prognosis of TBI.%目的 探讨超薄多层螺旋CT、颅骨三维图像重建和脑灌注成像在急性颅脑外伤动态变化中的临床应用价值.方法 收集2009年12月至2011年10月我院收治的245例急性颅脑外

  20. Experimental research and its clinical significance of precise postural adjustment and mean measurement by multi-slice spiral CT reconstruction of acetabular abduction angle%测量髋臼外展角度的实验研究及其临床意义MSCT三维重建精确体位调整均值法

    Institute of Scientific and Technical Information of China (English)

    范新成; 马振波; 于春丽; 朱海涛; 赵伟; 彭国庆; 张伟; 魏开斌; 刘峰

    2016-01-01

    Objective:To investigate the application of multi-slice spiral CT reconstruction accurate measurement of ace-tabular abduction angle,and to provide a scientific basis for guidance of total hip replacement acetabular prosthesis individu-alized accurate placement and postoperative evaluation. Methods:The research objects were 60 acetabulars of 30 pelvic spec-imens,and with anterior plane of pelvis as a reference plane,acetabular abduction angles were measured respectively by digital goniometer and multi-slice CT reconstruction with precise postural adjustment. Results:The acetabular abduction an-gle means of 30 pelvic specimens by digital goniometer and multi-slice CT reconstruction with precise postural adjustment were(48. 73 ± 3. 19)°and(48. 65 ± 2. 47)° respectively,and they had no significant difference(P > 0. 05). These data showed that the measurement of acetabular abduction angle by multi-slice CT reconstruction with precise postural ad-justment was accurate,which had no significant difference from the actual measurement. Conclusion:Multi-slice CT recon-struction with precise postural adjustment,with the anterior plane of the pelvis as a reference plane,is a new method of a preoperative acetabular abduction angle measurement for total hip arthroplasty,which can reduce human error in operation and achieve standardized measurement and evaluation of hip acetabular abduction angle.%目的:探讨应用 MSCT 三维重建精确测量髋臼外展角度的新方法,为指导全髋关节置换髋臼假体个体化准确置入及术后评估提供科学依据。方法选取30具骨盆标本共60个髋臼为研究对象,以骨盆前平面为参照平面,分别应用数显角度仪及 MSCT 三维重建精确体位调整均值法对髋臼外展角度数值进行测量,对两种方法的测量结果进行比较。结果应用数显角度仪及 MSCT 三维重建精确体位调整均值法测量髋臼外展角度分别为(48.73±3.19)°和(48.65±2.47)°

  1. Quantitative perfusion imaging by multi-slice CT in stroke patients; Quantitative Perfusionsbildgebung mittels Mehrschicht-Spiral-CT bei Patienten mit akuter zerebraler Ischaemie

    Energy Technology Data Exchange (ETDEWEB)

    Bohner, G.; Klingebiel, R. [Humboldt-Universitaet, Berlin (Germany). Universitaetsklinikum Charite, Abt. Neuroradiologie; Humboldt-Universitaet, Berlin (Germany). Universitaetsklinikum Charite, Inst. fuer Radiologie; Foerschler, A.; Lehmann, R. [Humboldt-Universitaet, Berlin (Germany). Universitaetsklinikum Charite, Abt. Neuroradiologie; Hamm, B. [Humboldt-Universitaet, Berlin (Germany). Universitaetsklinikum Charite, Inst. fuer Radiologie

    2003-06-01

    Objectives: Evaluation of a parametric deconvolution algorithm (DA) in the diagnostic assessment of stroke patients by multislice spiral computed tomography (MS-CT). Material and Methods: 52 patients (age range 34-89 years) with clinically suspected acute ischemia of one hemisphere and no infarct demarcation on plain cerebral CT underwent CT perfusion (CTP), performed on average 3.4 hours after the onset of symptoms by using MS-CT (4 x 8 mm scan volume). Using a DA-based software module, perfusion images of the cerebral blood perfusion (CBP), cerebral blood volume (CBV) and mean transit time (MTT) were calculated and assessed by two readers for visually apparent perfusion abnormalities. Amount and extension of perfusion disturbances were measured and correlated with the outcome. Results: Of 44 patients, in whom perfusion maps could be generated, territorial infarction was confirmed by follow-up in 22 subjects. With a sensitivity of 95% ischemia could be detected on MTT-maps (CBP 91%, CBV 77%). Specificity was highest (100%) for CBV-maps. Patients with infarction showed significant (p<0.001) reduction of CBP (10.7 vs. 38.3 ml/100 ml/min), CBV (1.3 vs. 2.3 ml/100 ml) and prolongation of MTT (12.3 vs. 4.3 s) compared to the contralateral hemisphere, whereas in patients without infarction no significant changes were found. Extension of CBV reduction showed the best correlation (r=0.82) with final infarct volume. Conclusion: The DA-based CTP protocol evaluated in this study is a suitable tool for the early identification and quantification of acute cerebral ischemia. (orig.) [German] Ziel: Evaluation des Einsatzes der Mehrschicht-Spiral-CT (MS-CT) in Kombination mit einem parametrischen Dekonvolutionsalgorithmus (DA) zur zerebralen Perfusionsbildgebung bei Patienten mit klinischen Zeichen einer akuten territorialen Ischaemie. Material und Methoden: 52 Patienten (Altersspanne 34-89 Jahre) mit klinischen Zeichen einer akuten territorialen Ischaemie sowie fehlender

  2. Multi-slice CT in the diagnosis of blunt laryngotracheal trauma%钝性喉气管损伤的MSCT诊断

    Institute of Scientific and Technical Information of China (English)

    王小鹏; 杨军; 刘伟

    2011-01-01

    目的:探讨多层螺旋CT在钝性喉气管损伤(B-LTT)中的临床应用价值.方法:对喉颈部外伤后156例患者使用GE LightSpeed 16层及32层螺旋CT设备行CT检查,其中平扫111例和对比剂增强扫描45例,并通过最大密度投影(MIP)、多平面重组(MPR)、仿真内镜(VE)及客积再现(VR)等影像后处理技术进行喉软骨、喉部软组织三维成像.结果:共发现43例患者喉部损伤,包括软组织损伤28例,喉软骨骨折14例及舌骨骨折1例.喉软骨骨折14例中,甲状软骨骨折12例(右侧甲状软骨5例,左侧甲状软骨骨折3例,甲状软骨前部正中骨折4例).同时合并环状软骨骨折3例,杓状软骨骨折2例,环杓关节脱位3例,环甲关节脱住2例.甲状腺损伤2例,皮下气肿12例,咽喉部血肿3例,颈2椎体骨折1例.MSCT显示喉软骨骨折的直接征象为喉软骨边缘不连续,可见低密度骨折线影,也可伴移位.软组织损伤表现为声门及气道狭窄,伴咽喉部血肿、皮下气肿.喉周围软组织内出现气泡是喉黏膜撕裂的间接征象.结论:螺旋CT可多方位显示喉软骨骨折部位、程度以及气道狭窄和喉黏膜撕裂情况,是诊断喉损伤快速有效的方法.%Objective : To evaluate the value of multi-slice spiral computed tomography (MSCT) in blunt laryngotracheal trauma ( B-LTT). Methods: MSCT was performed in 156 patients with BLTT including 111 patients had plain CT and 45 patients had enhanced CT.3-dimcnsional images of laryngeal cartilages and soft tissues were obtained with post-processing reconstruction techniques including MIP 、 MPR 、 VE and VR. Results: Altogether 43 patients were found to have laryngeal injuries including soft tissue injury ( n=28) ,laryngcal cartilage fracture ( n=14) and hyoid fracture ( n=1). In 14 patients having laryngeal cartilage fracture , there were thyroid cartilage fracture (n= 12 ; with right side , n= 5 ,left side.n= 3 ,anterior-median area n= 4). Concurrently complicated

  3. The clinical value of multi-slice spiral CT perfusion imaging in diagnosis of thyroid diseases%多层螺旋CT灌注成像在甲状腺疾病诊断中的临床价值

    Institute of Scientific and Technical Information of China (English)

    龚礼春

    2015-01-01

    ObjectiveTo investigate the clinical application value of multi-slice spiral CT perfusion imaging in diagnosis of thyroid diseases.Methods 112 patients with thyroid diseases in our hospital from January 2011 to December 2014 were selected as the research object. All patients with thyroid disease preoperatively received thyroid spiral CT scan, perfusion imaging and color Doppler ultrasonography, diagnosis and comparison of CT and ultrasound results and comparison of application effect in the differential diagnosis of benign and malignant thyroid lesions and imaging characteristics of spiral CT perfusion imaging.ResultsThe operation findings and pathology results was the gold standard, CT group detected thyroid benign lesions in 58 cases, 49 cases of malignant lesions, diagnosis rate was 95.54%, the diagnosis rate was significantly higher than the ultrasound group, and no significant difference compared with pathology results(P>0.05), has no statistical significance; Comparison of benign and malignant thyroid lesions of CT perfusion parameters known, benign and malignant lesions of blood volume (BV) and blood flow (BF) showed no significant difference, but the perfusion time to peak (TTP) and capillary permeability surface (PS) index comparison had the remarkable difference(P<0.05), was statistically significant.Conclusion The sensitivity and specificity for the diagnosis of thyroid diseases with high multi-slice spiral CT perfusion imaging and blood vessels, according to the pathological perfusion parameters and image difference can be accurately distinguish benign and malignant thyroid disease form, has the clinical value of application and popularization.%目的:探讨多层螺旋CT灌注成像在甲状腺疾病诊断中的临床应用价值。方法选取2011年1月~2014年12月我院收治的甲状腺疾病患者112例,作为研究对象。所有患者均以甲状腺疾病拟手术治疗术前进行甲状腺螺旋CT平扫、血管灌注成像及彩色多

  4. Bone, blood vessels, and muscle detection algorithm and creating database based on dynamic and non-dynamic multi-slice CT image of head and neck

    Science.gov (United States)

    Shabbir Ahamed, Mohammed; Kubo, Mitsuru; Kawata, Yoshiki; Niki, Noboru; Iwasaki, Hirokazu

    2007-03-01

    Nowadays, dental CT images play more and more important roles in oral clinical applications. Our research is important particularly in the field of dentistry. We are using non-dynamic and dynamic CT image for our research. We are creating our database of bone, blood vessels and muscles of head and neck. This database contains easy case and difficult case of head and neck's bone, blood vessels and muscle. There are lots of difficult cases in our database. Teeth separation and condylar process separation is difficult case. External carotid artery has many branches and they are attached with vain so it is difficult to separate. All muscle threshold value is same and they are attaching with each other so muscle separation is very difficult. These databases also contain different age's patients. For this reason our database becomes an important tool for dental students and also important assets for diagnosis. After completion our database we can link it with other dental application.

  5. Long-term follow-up of surgically excluded popliteal artery aneurysms with multi-slice CT angiography and Doppler ultrasound

    Energy Technology Data Exchange (ETDEWEB)

    Deglise, Sebastien; Haller, Claude; Corpataux, Jean-Marc [CHUV, Department of Thoracic and Vascular Surgery, Lausanne (Switzerland); Qanadli, Salah D.; Rizzo, Elena; Doenz, Francesco; Denys, Alban [University Hospital CHUV-University of Lausanne, Department of Radiology, Lausanne (Switzerland); Ducrey, Nicolas [CHUV, Department of Angiology, Lausanne (Switzerland)

    2006-06-15

    The purpose of this study was to evaluate the role of multi-slice computed tomography (MSCT) angiography in the follow-up of popliteal artery aneurysms (PAAs) that have been operated on. Aneurysm exclusion and progression, graft patency and graft-related complications were analyzed. Fourteen patients with 21 surgically excluded PAAs were evaluated with MSCT angiography with slice thickness of 1.25 mm. The mean follow-up time was 67 months. MSCT demonstrated blood flow in six non-excluded PAAs (24%), with an average increase in the diameter of 21 mm over time. Fifteen PAAs demonstrated no blood flow and revealed an average decrease of 7 mm in diameter. The origin of this residual perfusion was demonstrated, and collaterals were involved in five of six non-excluded PAAs. In addition, MSCT demonstrated three graft stenoses. Furthermore, two occluded grafts were visualized. Twenty-four percent of the patients after surgical exclusion of PAAs revealed residual perfusion within the aneurysmal sac during follow-up, with a significant increase in the aneurysmal size with MSCT. Moreover, evaluation of the graft patency could also be done as could demonstration of anastomotic abnormalities. Thus, MSCT might be considered as a new tool to evaluate residual collateral feeding of popliteal aneurysmal sac and could be useful in identification and localization of feeding vessels. (orig.)

  6. 多层螺旋CT在胆石性肠梗阻诊断中的价值%The value of multi-slice spiral CT in the diagnosis of gallstoneileus.

    Institute of Scientific and Technical Information of China (English)

    王兴龙; 李春荣

    2014-01-01

    目的:探讨多层螺旋CT在胆石性肠梗阻诊断中的价值。方法随机选取经过临床证实患有胆石性肠梗阻的患者16例,并对其临床资料进行分析。所有患者均接受了腹部超声和X先腹部平片以及CT平扫检查。结果16例患者多层螺旋CT均表现出胆石性肠梗阻征象。多层螺旋CT有100%的临床诊断准确率。结论多层螺旋CT对胆石性肠梗阻诊断中有极其重要的价值。%Objective To explore the multislice CT value in the diagnosis of gallstone ileus. Methods Randomly selected through clinical confirmed 16 cases of patients with gallstone ileus, and their clinical data were analyzed. All patients were accepted ab-dominal ultrasound and X first abdominal plain film and CT scan. Results MDCT results of 16 patients showed signs of gallstone ileus. Conclusion Multislice CT clinical diagnostic accuracy rate of 100%. Multi slice spiral CT has very important value in the diagnosis of gallstone ileus.

  7. 多排CT对小儿支气管内异物的诊断价值%Value of Multi Slice CT in Diagnosis of Bronchial Foreign Bodies in Children

    Institute of Scientific and Technical Information of China (English)

    冯锦兰

    2015-01-01

    Objective Comparative analysis of the diagnosis value of multi slice CT in the diagnosis of foreign bodies in children with bronchiolitis.Methods 76 children who were confirmed by fiberbronchoscope in our hospital were chosen, X-ray examination and 16 slice spiral CT examination were performed respectively, diagnosis accuracy of two methods were compared.Results The accordance rate of 16 slice spiral CT in the diagnosis of middle left bronchus, bronchus and right main bronchus were 100%, The direct indication of tracheal foreign body accounted for 88.1%, The indirect signs accounted for 11.9%; Clinical X-ray diagnosis coincidence rate was 85.5%, The direct signs accounted for 18.4%, The indirect signs accounted for 81.6%.the diagnosis rates of spiral CT were obviously higher than the X-ray, The difference had statistically significant(P<0.05). Conclusion Multi slice CT has high value in the diagnosis of bronchial foreign bodies in children.%目的:对比分析多排CT在诊断小儿支气管炎内异物的诊断价值。方法对我院进行治疗的经纤支镜确诊为支气管异物的患儿76例,分别对其进行X线检查及16排螺旋CT检查,对比观察两种检查方式的诊断准确性。结果76例患儿左支气管、主支气管及右主支气管异物应用16排螺旋CT诊断符合率为100%,其中直接提示气管异物占88.1%,间接征象占11.9%;X线临床诊断符合率为85.5%,其中直接征象占18.4%,间接征象占81.6%。螺旋CT对左支气管、中段支气管、右主支气管异物及总的诊断符合率均明显高于X线诊断符合率,差异有统计学意义(P<0.05)。结论多排CT对小儿支气管内异物具有较高的临床应用价值。

  8. Value of multi-slice spiral CT in the diagnosis of small hepatocellular carcinoma%多排螺旋CT灌注成像对小肝癌诊断价值

    Institute of Scientific and Technical Information of China (English)

    王恩峰; 陈文军; 苏保民; 程明; 赵新宇; 张立彬; 王丽梅

    2012-01-01

    Objective To study the diagnostic value of multi-slice spiral CT (MSCT) dynamic contrast-enhanced perfusion imaging in small hepatocellular carcinoma (SHCC) and improve the diagnostic accuracy of SHCC. Methods Multi-slice spiral CT dynamic contrast-enhanced perfusion imaging was used in 23 patients with SHCC, and the time-density curve(T-DC) were gotten. Blood flow( BF) , blood volume ( BV ) , hepatic arterial fraction ( HAF) , mean transit time(MTT) , permeability surface (PS) and time of arrival of SHCC and liver parenchyma were measured, and the colored perfusion maps for each of the above-mentioned parameters were acquired. Also the receiver operating characteristic curves ( ROC) were analyzed. Results SHCC showed BF,BV and HAF higher than those of the liver parenchyma(P 0. 05). T-DC of SHCC was fast rise, and its peak was significantly earlier than the liver parenchyma. Especially in hepatic arterial fraction determination, when ROC critical value was set to 0. 31, the sensitivity and specificity can be achieved respectively 100% and 90%. Conclusion Hepatic CT perfusion imaging is important for the diagnosis of small hepatocellular carcinoma.%目的 研究多排螺旋CT(multi-slice spiral CT,MSCT)动态增强灌注成像对小肝癌(small hepatocellular carcinoma,SHCC)的诊断价值,提高SHCC的诊断准确率.方法 使用多排螺旋CT对23例小肝癌患者行动态增强灌注成像,生成时间-密度曲线(time-density curve,T-DC),测量肝癌病灶及肝实质的CT灌注值包括血流量(blood flow,BF)、血容量(blood volume,BV)、肝动脉分数(hepatic arterial fractin,HAF),平均通过时间(mean transit time,MTT)、血管表面通透性(permeability suface,PS)和对比剂到达时间,并获得相应的灌注伪彩图.分析接受者工作特征曲线(receiver operating characterisic curves,ROC).结果 小肝癌血流量、血容量及肝动脉分数值均明显高于肝实质(P<0.05),其它的灌注值在两者

  9. Post-processing techniques of multi-slice spiral CT in normal orbital related structures%MSCT后处理技术在眶骨正常解剖中的应用

    Institute of Scientific and Technical Information of China (English)

    李晓; 李春卫; 张峰峰; 徐卓东

    2011-01-01

    Objective: To explore the value of post-processing techniques of multi-slice spiral CT(MSCT) in normal orbiral related structures. Methods: 207cases with the source images of normal orbit were retrospectively reviewed and processed using multiple planar reformation ( MPR) , curved planar reformation (CPR ) , volume rendering rechnique ( VRT).The show results of conventional and reconstructed sections were statistically analysed. Results : The orbital related structures can be display symmetrically by the standard section. The display rate of sutura nygomaticofrontalis. the canal of temporal bone , infraorbital canal, supraorbital notch and optic canal in the standard section was significantly higher than in conventional images ( P <0.05). There was no difference in the display rate of the sutura zygomaticosphenoidalis ( P >0. 05), Conclusion:① The post-processing of multi-slice CT isotropic scanning can reduce the radiation dose and avoid the difficulty in positioning patient;② The orbital related structures can be display very well after post processing with multislice CT isotropic scanning by using the post-processing rechniques.%目的:探讨多层螺旋CT后处理技术在眶骨正常相关结构中的应用价值.方法:收集207例正常眶骨被检者的多层螺旋CT图像,对所得图像进行MPR,CPR,VRT后处理,对某些结构常规显示断面和标准化断面的显示结果进行统计学分析.结果:重组后的标准化图像能清晰显示眶骨相关结构的左右对称情况.标准化图像对颧额缝、颧骨管、眶下管、眶上切迹及视神经管的对称性显示明显优于常规扫描图像(P<0.01):而对颧蝶缝的显示无明显差异(P>0.05).结论:①利用多层螺旋CT各向同性扫描进行后处理在避免摆位困难的同时,减少了患者的辐射剂量;②多层螺旋CT各向同性扫描结合多种后处理技术能够很好地对称显示眼眶相关结构.

  10. Assessment of volumetric bone mineral density of the femoral neck in postmenopausal women with and without vertebral fractures using quantitative multi-slice CT

    Institute of Scientific and Technical Information of China (English)

    Sheng-yong WU; Hui-hui JIA; Didier HANS; Jing LAN; Li-ying WANG; Jing-xue LI; Yue-zeng CAI

    2009-01-01

    Objective: To demonstrate the validity and reliability of volumetric quantitative computed tomography (vQCT) with multi-slice computed tomography (MSCT) and dual energy X-ray absorptiometry (DXA) for hip bone mineral density (BMD) measurements, and to compare the differences between the two techniques in discriminating postmenopausal women with osteoporosis-related vertebral fractures from those without. Methods: Ninety subjects were enrolled and divided into three groups based on the BMD values of the lumbar spine and/or the femoral neck by DXA. Groups 1 and 2 consisted of postmenopausal women with BMD changes <-2SD, with and without radiographically confirmed vertebral fracture (n=11 and 33, respectively).Group 3 comprised normal controls with BMD changes ≥-1SD (n=46). Post-MSCT (GE, LightSpeed16) scan reconstructed images of the abdominal-pelvic region, 1.25 mm thick per slice, were processed by OsteoCAD software to calculate the following parameters: volumetric BMD values of trabecular bone (TRAB), cortical bone (CORT), and integral bone (INTGL) of the left femoral neck, femoral neck axis length (NAL), and minimum cross-section area (mCSA). DXA BMD measurements of the lumbar spine (AP-SPINE) and the left femoral neck (NECK) also were performed for each subject. Results: The values of all seven parameters were significantly lower in subjects of Groups 1 and 2 than in normal postmenopausal women (P<0.05, respectively).Comparing Groups 1 and 2, 3D-TRAB and 3D-INTGL were significantly lower in postmenopausal women with vertebral fracture(s) [(109.8±9.61) and (243.3±33.0) mg/cm3, respectively] than in those without [(148.9±7.47) and (285.4±17.8) mg/cm3,respectively] (P<0.05, respectively), but no significant differences were evident in AP-SPINE or NECK BMD. Conclusion: the femoral neck-derived volumetric BMD parameters using vQCT appeared better than the DXA-derived ones in discriminating osteoporotic postmenopausal women with vertebral fractures from

  11. Comparative Analysis on Two Intestinal Preparation Methods in Multi-Slice Spiral CT Enterography%两种肠道准备方法在多层螺旋CT小肠造影中的对比分析

    Institute of Scientific and Technical Information of China (English)

    杜志顺

    2014-01-01

    目的:探讨两种肠道准备方法在多层螺旋CT小肠造影中的对比效果.方法选取行多层螺旋CT小肠造影的患者152例,根据肠道准备方法分为两组,76例患者先行肥皂水清洁灌肠后口服泛影葡胺充盈肠道为对照组,76例患者口服甘露醇和泛影葡胺混合水溶液充盈肠道为观察组,比较两组患者的服药依从性、检查舒适度、肠道充盈效果、造影图像质量、不良反应情况.结果观察组患者的服药依从性、检查舒适度、肠道充盈效果的有效性均明显好于对照组,观察组患者造影图像质量的优良率明显高于对照组,观察组患者不良反应发生率明显低于对照组,差异均有统计学意义(P<0.05).结论甘露醇和泛影葡胺混合水溶液充盈肠道是多层螺旋CT小肠造影的有效肠道准备方法,可显著提高患者的服药依从性和检查舒适度,明显改善患者的肠道充盈效果和造影图像质量,引发的不良反应较少,具有较高的操作安全性,值得临床推广使用.%Objective To investigate the comparative effect of two intestinal preparation methods used in multi-slice spiral CT enterography. Method 152 patients who underwent multi-slice CT enterography were divided into two groups. 76 patients treated with oral urografin intestinal tract filling after the cleaning enema by soap solution were taken as control group. 76 patients treated with oral mixed mannitol and meglumine diatrizoate water solution intestinal tract filling gut were taken as observation group. The compliance,degree of comfort,intestinal tract filling effect, image quality and adverse reactions of patients in two groups were compared. Results The compliance,degree of comfort and effect of intestinal tract filling in the observation group were significantly better than those in the control group. The excellent and good rates of angiography image quality in the observation group were significantly higher than those in the

  12. The value of multi-slice spiral CT enterography in the diagnosis of small bowel tumors%多层螺旋CT小肠造影对常见小肠肿瘤的诊断价值

    Institute of Scientific and Technical Information of China (English)

    饶圣祥; 曾蒙苏; 张利军; 陈刚; 陆秀良; 刘红春

    2012-01-01

    目的 探讨口服甘露醇多层螺旋CT小肠造影(multi-slice spiral CT enterography,MSCTE)对小肠肿瘤检出的价值以及分析常见小肠肿瘤的CT特征.方法 回顾性分析135例患者的MSCTE图像,由2名放射科医生评价,分析小肠是否存在肿瘤和小肠肿瘤MSCTE表现特点.结果 最终证实小肠肿瘤26例,包括胃肠道间质瘤10例,淋巴瘤8例,腺癌6例,类癌2例.2位阅片者的敏感性、特异性、阳性预测值及阴性预测值平均值分别为90.39%,97.25%,88.75%及97.7%.2位阅片者之间结果 的一致性的Kappa值为0.925.胃肠道间质瘤、淋巴瘤和腺癌在强化方式、形态改变以及是否伴淋巴结肿大等具有各自的特点.结论 口服甘露醇MSCTE对小肠肿瘤的检出准确性高,对常见小肠肿瘤的诊断与鉴别诊断有重要的临床应用价值.%Objective To evaluate the diagnostic accuracy of multi-slice spiral CT enterography (MSCTE) with orally administrated isosmotic mannitol in the detection of small bowel tumors, and to identify characteristics of common small bowel tumors through images of MSCTE. Methods MSCTE images of 135 patients were independently reviewed retrospectively by 2 radiologists and MSCTE findings of different types of small bowel tumors were analyzed. Results Histopathologic diagnoses were as follows:gastrointestinal stromal tumors(GIST) (n=10), lymphoma (n=8), primary small-bowel adenocarcinoma (n=6), carcinoid tumor (n= 2). The mean sensitivity, specificity ,PPV,NPVwere 90.39%,97.25%,88.75%,97.7% respectively. The value of Kappa was 0. 925 between the two readers. The common small bowel tumors mainly including GIST, lymphoma and adenocarcinoma had respective characteristics in the enhancement pattern , tumor shape and mesenteric lymph nodes at MSCTE. Conclusion MSCTE with orally administrated isosmotic mannitol is an accurate modality for detecting and characterizing small bowel tumors.

  13. 多排螺旋CT与CR在肋骨骨折诊断中的比较%Comparison of Multi-slice Spiral CT and CR in Rib Fracture

    Institute of Scientific and Technical Information of China (English)

    高雷

    2016-01-01

    Objective Evaluation of row Multi-slice Spiral CT and CR use value in the diagnosis of rib fracture, and to discuss the advantages of two different methods in the diagnosis of rib fracture, so look for ways to improve the accuracy of diagnosis. Methods Retrospective analysis of 60 patients who check rib fracture from 2014 to 2015 in our hospital because of chest trauma. The patients were randomly divided into CT inspection group and CR inspection group, and each group of 30 cases. Among them CT inspection group: male 19, female 11; CR inspection group: male 17, female 13. Two radiologists doctor diagnosis with double-blind method. Results 1 ~ 3 ribs: The diagnostic accuracy of CT was 46.3% (25/54), and the diagnostic accuracy of CR was 74.4% (32/43);4~8 ribs:The diagnostic accuracy of CT was 88.5% (119/135), and the diagnostic accuracy of CR was 55.1% (81/147); 9~12 ribs: The diagnostic accuracy of CT was 91.7% (55/60), and the diagnostic accuracy of CR was 53.2% (33/62). False positive misdiagnosis rate of CT was 15.1% (71/471), and false positive misdiagnosis rate of CR was 7.1% (33/468). Conclusion Multi-slice spiral CT and CR each other and cooperate with the inspection can effectively improve the accuracy of diagnosis of rib fracture, meanwhile reduce missed diagnosis and misdiagnosis rate.%目的:评价多排螺旋CT与CR在肋骨骨折诊断中的运用价值,探讨两种检查方法各自诊断肋骨骨折的优势,寻找提高诊断准确性的检查方法。方法回顾性分析2014~2015年60例因胸部外伤后来我院行影像学检查诊断有无肋骨骨折的患者。将患者随机分为CT检查组和CR检查组,每组30例。其中CT检查组:男19例,女11例;CR检查组:男17例,女13例。由放射科两名主治医师采用双盲法进行诊断。结果第1~3肋骨:CT诊断准确率为46.3%(25/54),CR诊断准确率为74.4%(32/43);第4~8肋骨:CT诊断准确率为88.5%(119/135),CR诊断准确率为55.1%(81/147);第9~12

  14. Improvement Techniques and Experiment Research of Multi-detector of Multi-slice CT%对多层CT的多排探测器的改进技术及实验研究

    Institute of Scientific and Technical Information of China (English)

    苏重清; 刘东红; 杨立国; 乔驰; 陶行成; 崔力元; 郑伟; 郭媛媛

    2013-01-01

    Objective To design a new kind of multidetector for multi-slice CT, so as to decrease X-ray dosage and increase resolution. Methods Laid additional detectors under the detectors of CT, to obtain new X-ray energy and new resolution data through the upper detectors and make various images with original detector data. Results Laid a layer of X-ray attenuation material on the present detectors of CT as the first layer detector and regarded the present detector as the second layer detector in the design to scan, the second layer detector data is testified available. Conclusion Through simulating tests on present CT scanner, the design is testified to be feasible.%目的 设计一种新型多层CT机的多排探测器,降低X线剂量和提高分辨率.方法在CT探测器下面再加探测器,接收穿透上层探测器的X线获得能量与分辨率不同的额外数据,和原来探测器数据做各种形式的叠加成像.结果在现有CT探测器上加X线衰减层模拟第1层探测器而视现有CT探测器为本设计的第2层探测器扫描,证明了第2层探测器的数据可用.结论通过在现有CT上的模拟实验,证明此设计是可行的.

  15. 中央型小细胞肺癌和鳞癌的多层螺旋CT表现分析%Analysis of Multi Slice Spiral CT in Central Type Small Cell Lung Cancer and Squamous Cell Carcinoma

    Institute of Scientific and Technical Information of China (English)

    陈亮

    2016-01-01

    目的:对中央型小细胞肺癌和鳞癌的多层螺旋 CT 表现进行分析探讨,为今后的临床诊断工作,提供有价值的参考信息。方法选择2014年8月~2015年5月我院收治的获得明确诊断的,中央型小细胞肺癌与鳞癌患者共计48例作为研究对象,对其展开多层螺旋 CT 检查,并对检查资料展开回顾性分析。结果观察发现,中央型小细胞肺癌患者的胸膜腔存在积液、远处有转移、支气管狭窄无阻塞、心脏大血管受到侵害、肺叶发生实变、纵隔肺门淋巴结肿大、淋巴结融合发生率较鳞癌患者高(P <0.05);对比发现,两组患者心包腔积液、胸膜结节、支气管不全性阻塞、肺不张发生率比较,差异无统计学意义(P >0.05)。鳞癌患者肿瘤不均匀强化、坏死、支气管闭塞发生率较中央型小细胞肺癌高(P <0.05)。结论中央型小细胞肺癌、鳞癌患者的多层螺旋 CT 表现存在一定差异,综合分析,可做出准确鉴别。%Objective Purpose of center type smal cel lung cancer and squamous cel carcinoma of the multislice spiral CT findings were analyzed for future clinical work,providing valuable reference information. Methods From August 2014 to May 2015,our hospital access to diagnosis,central smal cel lung cancer in patients with squamous cel carcinoma of 48 cases studied,the multi-slice spiral CT examination and check the information retrospectively. Results Observed that patients with central type smal cel lung cancer pleural cavity effusion,distant have transfer,bronchial stenosis,non blocking, heart and great vessels have been infringed,lobar occur consolidation,mediastinal and hilar lymph nodes,lymph node fusion rate is high in patients with squamous cel carcinoma(P 0.05)in two groups of patients with pericardial effusion, pleural nodules,bronchial obstruction,and the incidence of lung failure. The incidence of non homogeneous enhancement

  16. Effects of Sennae Folium Combined with Mannitol on Multi-slice Spiral CT Bowel Imaging%番泻叶联合甘露醇肠道清洁对多层螺旋CT肠道成像的影响

    Institute of Scientific and Technical Information of China (English)

    项微微; 刘克昌; 殷焱

    2016-01-01

    OBJECTIVE:To evaluate the effects of Sennae Folium combined with mannitol for bowel cleaning on multi-slice spiral CT bowel imaging. METHODS:52 patients receiving multi-slice spiral CT imaging examination in our hospital during Jun. 2011 to Jun. 2012 were collected retrospectively,and then divided into control group(22 cases)and observation group(30 cases) according to the methods of bowel preparation. Both groups fasted for 12 h before examination. Sennae Folium 20 g soaked in boiled water 500 ml for half an hour was given to patients in control group 12 h before examination,and then was soaked in boiled water 500 ml again for drinking and other pure water 1 000 ml was also given to patients. Sennae Folium 10 g soaked in boiled wa-ter 500 ml was given to patients in observation group 1 d before examination and 2 h after breakfast;soaked in boiled water 500 ml again 2 h after lunch;10% mannitol 500 ml and pure water 1 000 ml were given to patients after supper. Both groups received multi-slice spiral CT bowel imaging until the patients defecated watery stool after medication. The effective rate of bowl cleaning, image quality and the incidence of ADR were compared between 2 groups. RESULTS:The effective rate of bowel cleaning was 100% in observation group,which was significantly higher than that of control group(81.82%),with statistical significance(P<0.05). The excellent and good rate of imaging quality was 96.67% in observation group,which was significantly better than that of control group(81.82%),with statistical significance(P<0.05). The incidence of ADR as abdominal distension,nausea,intestinal mucosa damage in observation group were significantly lower than those of control group,with statistical significance (P<0.05). CONCLUSIONS:Sennae Folium combined with mannitol is effective method to prepare enteric multi-slice spiral CT imaging exam-ination,and perform good bowl cleaning effect,high image quality and low incidence of ADR.%目的:评价番泻叶联合

  17. 胰腺导管内乳头状黏液性肿瘤的MSCT和MRCP诊断%Multi-slice CT and MR cholangio-pancreatographic diagnosis of intraductal papillary mucinous neoplasm of the pancreas

    Institute of Scientific and Technical Information of China (English)

    张超; 弓静; 郭帅; 殷长均

    2011-01-01

    Objective To evaluate the multi- slice CT (MSCT) and magnetic resonance cholangio- pancreatography (MRCP) features of intraductal papillary mucinous neoplasm (IPMN) ofthe pancreas.Methods The CT and MRCP of 26 cases of IPMN including adenocarcinoma (6 cases), borderline malignancy (2), and adenoma (1) were reviewed.Results CT and MRI of IPMN in the pancreatic ductal branches (12 cases) showed solitary or multiple cystic lesions with septa or nodules in the ducts.In the 5 patients with main pancreatic duct IPMN, there was dilation of the main pancreatic duct with mural nodule.In 9 patients with mixed type pancreatic IPMN, dilation of the main pancreatic duct and cystic lesions were noted.Conclusion MSCT and MRCP are useful in the diagnosis ofpancreatic IPMN.%目的 探讨胰腺导管内乳头状黏液性肿瘤 (IPMN)的MSCT和MRCP影像学表现.方法 对26例经内镜或手术病理证实的IPMT患者的CT和MRCP表现进行回顾性分析.结果 分支胰管型IPMN12 例,表现为单发囊性病变或葡萄串样多发囊性病变伴腔内分隔或结节样突起;主胰管型 IPMN 5 例,表现为主胰管扩张伴管壁结节样突起;混合型IPMN 9例,表现为主胰管扩张和囊性病变合并存在.9例手术病理结果为腺瘤1例,交界性肿瘤2例,腺癌6例.结论 MSCT和MRCP对发现和诊断胰腺 IPMN具有较高价值.

  18. A differentiated approach to the diagnosis of pulmonary embolism and deep venous thrombosis using multi-slice CT; Abklaerung von Lungenembolie und venoeser Thromboembolie mittels Mehrschicht-Spiral CT

    Energy Technology Data Exchange (ETDEWEB)

    Wildberger, J.E.; Mahnken, A.H.; Stargardt, A.; Haage, P.; Guenther, R.W. [Klinik fuer Radiologische Diagnostik (Germany); Sinha, A.M. [Medizinische Klinik 1, Universitaetsklinikum der RWTH Aachen (Germany); Schaller, S. [Siemens Medical Solutions, Computertomographie, Forchheim (Germany)

    2002-03-01

    Purpose: To establish a differentiated protocol for multi-slice CT (MSCT) examinations in cases of clinically suspected pulmonary embolism (PE) using pulmonary CT-angiography (CTA) and indirect CT-phlebography (CTP). Materials and Methods: 161 patients with suspected PE were examined using an MSCT (SOMATOM Volume Zoom; Siemens, Forchheim, Germany). After intravenous administration of 120 ml of contrast material, a thin collimation chest-CT scan was performed (120 kV, 100 mAs, collimation: 4 x 1 mm). If PE was present, or previous examinations and clinical signs suggested deep venous thrombosis (DVT), a CTP was subsequently completed. CTPs were performed using a 4 x 5 mm protocol (120 kV, 170 mAs). Venous phase scanning, starting from the pelvic crest, was completed in the popliteal fossa three minutes after contrast material injection. In 73 extremities, CTP were compared to the results of ultrasound, phlebography and autopsy. Scan ranges were documented in all patients. Cumulative doses were calculated for male and female subgroups. Results: 62 patients in our series suffered from PE and in 47 of these patients deep venous thrombosis was seen additionally. Of the 99 patients without PE, 47 also received indirect CTP. CTP confirmed the suspicion and extent of DVT in 8 patients. Only in 2 of 39 patients (5.1%) was previously unknown DVT found, despite the exclusion of PE. Regarding DVT, sensitivity was 94.3% and specificity was 92.1% for indirect CTP. Cumulative chest CT doses averaged 3.3 mSv for males and 4.2 mSv for females, the calculated CTP dosage was 9.3 mSv (according to ICRP 60). Conclusions: the examination protocol presented its suitable for clinical usage in patients with suspected PE. If PE is confirmed, indirect CTP is justified, so that detailed information of the venous system can be obtained. However, the relatively high radiation dosage of an additional CTP requires a strict indication regiment in patients with a negative CTA. (orig.) [German

  19. 多发性大动脉炎的多层螺旋CT诊断%Diagnosis of Takayasu's arteritis with multi-slice spiral CT

    Institute of Scientific and Technical Information of China (English)

    平学军; 孟淑萍; 汪芳

    2008-01-01

    目的 分析总结多发性大动脉炎(TA)的多层螺旋CT检查方法及CT 征象,提高TA的CT诊断水平.方法 回顾性分析20例TA的多层螺旋CT检查资料,总结CT 检查方法及CT 表现并结合文献进行分析讨论.结果 按照Lupi-Herrea分类法,包括Ⅰ型5例,Ⅱ型3例,Ⅲ型12例.受累血管48支. CT 表现包括:受累血管管壁增厚48支、管腔狭窄46支、闭塞2支,2例并有血管瘤样扩张.结论 正确选择多层螺旋CT检查方法, 能够为TA的正确诊断提供可靠信息.

  20. Evaluation of multi-slice spiral CT perfusion on blood supply of rabbits model bearing VX2 hepatic carcinoma%多排螺旋CT灌注成像对兔VX2肝癌血供的评价

    Institute of Scientific and Technical Information of China (English)

    周悦; 高剑波; 杨学华; 张永高; 岳松伟; 曲艳红

    2011-01-01

    Aim:To assess the diagnostic value of Muhi-slice CT perfusion for blood supply evaluation of the rabbits VX2 hepatic tumors. Methods: VX2 hepatic carcinoma mass were implanted into the left lobe of liver of 30 rabbits via laparotomic route. Multi-slice CT enhancement and perfusion were performed in these rabbits at twenty-one day after implantation. The CT imaging features of the tumors were observed and the perfusion parameters were measured in the rim of the tumor, non-tumorous regions nearby the tumor and the normal liver tissues. Results: Twenty-five (83%) rabbits were sucessfully implanted with the tumor. The tumors which has smooth border were demostrated itself as the round-shaped tumors with hypodensity on plain CT scan,significantly tinge-enhancement on arterial phase, relatively hypodensity on portal phase and no enhanced in the zone of necrosis. Blood flow, blood volume, permeability surface, hepatic arterial fraction, hepatic arterial perfusion increased and mean transit time decreased in the rim of the tumor compared with those of the non-normorous regions nearby the tumor and the normal liver ( P < 0.05). Conclusion: Multi-slice CT perfusion could evaluate the blood supply station of hepatic tumors in vivo by perfusion parameters.%目的:探讨多排螺旋CT灌注成像对兔VX2肝癌血供的评价价值.方法:采用开腹瘤组织块直接包埋法将VX2肝癌移植瘤植入30只新西兰大白兔肝左叶,并于种植后第21天行多排螺旋CT增强及灌注扫描,观察其CT征象,并对比肿瘤边缘区、瘤旁肝组织以及对照肝组织的CT灌注参数(血流量、血容量、平均通过时间、表面通透性、肝动脉分数以及肝动脉灌注量).结果:25只(83%)大白兔种植成功.CT平扫肿瘤为类圆形低密度灶;增强动脉期病灶表现为边缘环状强化;门脉期呈相对低密度,中心见低密度坏死区,与周围组织界限较清.CT灌注成像结果:肿瘤边缘区、瘤旁肝组织及对照肝

  1. 多层螺旋CT骨三维重建在肋骨及肋软骨骨折的诊断价值%The Diagnostic Value of Multi-slice Spiral CT 3D Bone Reconstruction on Rib and Rib Cartilage Fractures

    Institute of Scientific and Technical Information of China (English)

    苏杨; 刘静; 王江玥

    2016-01-01

    Objective To explore the application value of multi-slice spiral CT (MSCT) three-dimensional (3D) bone reconstruction on the diagnosis of rib and rib cartilage fractures.Methods Forty-three cases of patients with chest injury were treated as the study objects. All of them underwent multi-slice spiral CT scanning. Volume rendering (VR), maximum intensity projection (MIP) and multi planar reconstruction (MPR) were used for 3D reconstruction of ribs and rib cartilage. Compared with routine CT scan, the diagnostic advantages of MSCT 3D reconstruction were analyzed.Results Forty-three cases had rib fractures, a total of 122 ribs. Single fractures accounted for 30.23% and multiple fractures accounted for 69.77%; The axillary segment of rib fracture was common, accounting for 95.65%, 15 cases had rib cartilage fractures, a total of 23, 24 cases were detected with complications by MSCT. The accuracy rate of MSCT 3D reconstruction in the diagnosis of rib and rib cartilage fractures (98.36%, 95.65%) were significantly higher than those of CT scan (72.95%, 13.04%) (P<0.05).Conclusion The accuracy of MSCT in the diagnosis of rib and cartilage fractures is high. It can be used as an ideal imaging method for the diagnosis of the disease.%目的:探讨多层螺旋CT(multi-slice spiral computed tomography, MSCT)骨三维重建在诊断肋骨及肋软骨骨折中的应用价值。方法选取43例胸部外伤患者为研究对象,均行多层螺旋CT扫描,运用容积重建(volume rendering, VR)、最大密度投影(maximum intensity projection, MIP)、多平面重建(multi planar reconstruction, MPR)三维重建肋骨及肋软骨,并与常规CT平扫对比,分析MSCT三维重建的诊断优势。结果43例肋骨骨折,共122根;其中单发骨折占30.23%,多发骨折占69.77%;肋骨骨折腋段较为常见,占95.65%;15例肋软骨骨折,共23根;MSCT检出24例外伤后并发症。MSCT三维重建技术诊断肋骨及肋软骨骨折的准确率为98

  2. 肺挫伤患者多层螺旋CT影像学表现与预后%Association of multi-slice spiral CT images of occult pulmonary contusion with disease prognosis

    Institute of Scientific and Technical Information of China (English)

    王凌; 唐怨; 孔德会; 陈友强; 付子文; 杨华

    2014-01-01

    探讨肺挫伤(occult pulmonary contusion,OPC)患者多层螺旋CT(multi-slice spiral CT,MSCT)影像学表现与预后.对143例胸部钝性伤后行常规胸部正位平片和MSCT检查患者影像及临床资料进行回顾性分析.共87例患者检出肺挫伤,其中显性挫伤58例,24例继发肺炎,13例继发脓胸,16例继续发展为急性呼吸窘迫综合征(ARDS);隐匿性肺挫伤(OPC)29例,6例继发肺炎,1例发展为ARDS,未见继发脓胸患者;其余56例中7例继发肺炎,1例继发ARDS,未见继发脓胸患者.在OPC患者中,所有挫伤局限于一个肺叶的患者临床预后均较好;所有继发肺炎的患者挫伤范围均大于两个肺叶.OPC患者总体临床预后较好,MSCT能可靠的评价挫伤的范围,对OPC患者的临床治疗具有一定的指导意义.

  3. The Effects Analysis of Multi-slice Spiral CT Perfusion Imaging of Different Parts of Normal Pancreas%正常胰腺不同部位的多层螺旋CT灌注成像效果分析

    Institute of Scientific and Technical Information of China (English)

    黄英荷; 杜绪仓

    2013-01-01

    目的:对正常胰腺不同部位的多层螺旋CT灌注成像效果进行分析。方法:抽取行中上腹部CT增强检查而胰腺正常的病例20例作为研究对象,对其胰腺头部、体部以及尾部感兴趣区层面进行CT灌注扫描,对采集的影像数据使用相关灌注软件进行计算,并对灌注参数进行统计学分析。结果:患者正常胰腺的头部、体部以及尾部的灌注参数均无统计学意义,P>0.05。结论:正常胰腺的头部、体部以及尾部的CT灌注参数基本一致。%Objective:To analyze the multi-slice spiral CT perfusion imaging effects of different parts of the normal pancreas Methods:20 patients with normal pancreas were included in this study from January 2010 to December 2011. All Cases underwent contrast-enhanced CT scan and perfusion imaging with pancreatic head,body and tail which included the region of interest (ROI). The perfusion parameters were calculated and statistically analyzed by using the correlational perfusion software. Results:There were not significantly perfusion parameters difference among the head, body and tail of pancreas, P>0.05.Conclusion:The perfusion parameters of normal pancreatici are even consistent.

  4. Value of Multi-Slice Spiral CT in the Diagnosis of Atypical Appendicitis%多排CT对非典型阑尾炎的诊断价值

    Institute of Scientific and Technical Information of China (English)

    李水婷; 江魁明; 麦慧; 张家云; 侍丽

    2013-01-01

    To investigate the value of the multi-detector row computed tomography in the diagnosis of appendicitis with atypical clinical feature. Methods: 58 cases of appendicitis which were not initially considered on clinical presentation, were confirmed surgically and pathologically were collected, CT characteristics were retrospectively analyzed. Results: 54 of the 58 patients were correctly diagnosed on CT. It included: 6 cases of dissect abnormal appendicitis, 22 cases of women of childbearing age appendicitis. 19 cases of elderly appendicitis. 11 cases of pediatric appendicitis. The direct CT signs of acute appendicitis were an charged appendix with wall thickening and appendicolith. Indirect signs included appendiceal perityphlitis and periappendicular. Conclusion: Multi-detector row computed tomography is valuable for early diagnosis of appendicitis with atypical clinical feature.%目的:探讨多排CT对缺乏典型临床表现的阑尾炎的应用价值.材料方法:搜集2010年1月~2012年1月临床首诊未考虑阑尾炎,经手术、病理证实为阑尾炎患者58例,回顾分析其CT表现.结果:58例阑尾炎患者中CT术前诊断为阑尾炎54例,渗断准确率93%.其中:解剖位置异常的阑尾炎6例;育龄妇女急性阑尾炎22例;老年急性阑尾炎19例;小儿急性阑尾炎11例.急性阑尾炎CT直接征象:阑尾肿胀、阑尾壁增厚及阑尾结石.CT间接征象:阑尾周围炎、阑尾周围脓肿.结论:使用多排CT对临床早期明确非典型阑尾炎的诊断有重要意义.

  5. 腹股沟疝和股疝的多层螺旋CT表现%The Findings of Inguinal Hernia and Femoral Hernia on Multi-slice Spiral CT

    Institute of Scientific and Technical Information of China (English)

    潘华山; 匡楚龙; 蔡云国; 陈容; 孙春梅

    2012-01-01

    目的 研究腹股沟疝和股疝的多层螺旋CT (multi-slice spiral CT,MSCT)表现,探讨如何通过MSCT对腹股沟疝和股疝做出诊断与鉴别诊断.方法 回顾性分析30例经手术证实的腹股沟疝和股疝MSCT包括多平面重组(multiplanar reformation,MPR)表现,重点观察疝的位置、形态、走行、内容物及与周围结构间的关系以及继发征象.结果 MSCT诊断腹股沟斜疝16例,腹股沟直疝11例,股疝3例.16斜疝中12例有腹股沟深环的扩大,16例显示腹股沟管的扩大.以耻骨结节为参考点,10例斜疝和4例直疝跨越中线位于外上象限和内上象限,3例股疝则位于外下象限.3例股疝中2例显示股静脉受压变形.结论 MSCT能够显示腹股沟疝和股疝的位置、形态、走行、内容物、与周围结构之间的关系及并发症,能够为腹股沟疝和股疝的诊断与鉴别诊断提供有价值的信息.对于腹股沟疝和股疝的诊断与鉴别诊断,应综合观察腹股沟管、腹股沟管深环的改变以及疝与腹壁下血管、股血管、腹股沟韧带的关系,并重视多平面重组在诊断中的应用价值.%Objective To study the multi-slice spiral CT (MSCT) features of hernia of inguinal hernia and femoral hernia, and to explore the diagnosis and differential diagnosis of inguinal hernia and femoral hernia with MSCT. Methods 30 cases with inguinal hernia and femoral hernia confirmed by operation were retrospectively analyzed. All cases were undergone the MSCT examination. The key point of observation was the position, course, herniated contents, adjacent structures as well as complications. Result A total of 30 subjects were enrolled in this study, 16 were indirect inguinal hernia, 11 were direct hernia, 3 were femoral hernia. 12 indirect hernia displayed enlargment of the groin deep ring, and 16 indirect hernia showed enlargment of the inguinal canal. When took the pubic tubercle as the point of reference, 10 indirect hernia and 4 direct

  6. 多层螺旋CT肛缘定位的研究%The anal verge: localization with multi-slice spiral CT

    Institute of Scientific and Technical Information of China (English)

    汪伟; 唐光健

    2010-01-01

    Objective To determine and evaluate the method of localization of anal verge by mutislice spiral CT. To provide an imaging reference for operative guidance of low-rectal cancer. Methods Forty eight consecutive adult patients suspected of abnormalities other than rectal disease were evaluated with abdominal and pelvic CT scans since August, 2009. They were divided into two groups based on sex and age. There were 23 men and 25 women. The ages of young group were 28 to 50 years and the average age was 41 years. The ages of elderly group were 52 to 81 years and the average age was 64 years. A small cotton ball dipped with contrast media was put at the anal verge as a marker and CT scans were performed with 64-slice spiral CT scanner. The distances between the cotton balls and the lower margin of the pubis combination (La), the lower margin of the 5th sacral vertebra (Lb), the inferior aperture of minor pelvis(Lc) and the lower margin of the basement of external anal sphincter (Ld) were measured on the midsagittal images obtained by MPR. The averages, the standard deviations(s), the 95% and 80% confidence intervals of La, Lb, Lc and Ld were calculated. We took the intervals of ± 1.96 s or ± 1.28 s < 5 mm as the standard of meeting the clinical requirement. The distances meeting the clinical requirement between different sex groups or age groups were compared with t test. Results The Ld was (9.8 ± 1.2) mm, ofwhich intervals of ± 1.96 s and ± 1.28 s were 4. 8 mm and 3.0 mm respectively, meeting the clinical need.This distance was also measured conveniently. There were no significant differences ( P > 0.05 ) between two different sex groups [ male group, ( 10.0 ± 1.2) mm], female group, (9.6 ± 1.2) mm and between two age groups [ young group, (9.6 ± 1.2) mm, elderly group, ( 9.9 ± 1.3 ) mm ]. Conclusions The lower margin of the basement of external anal sphincter was a useful anatomic lanmark for localizing the anal verge,and could be definitely identified on

  7. The role of multi-slice spiral CT in diagnosis and treatment of lumbar hernia%多层螺旋 CT 在腰疝诊治中的意义

    Institute of Scientific and Technical Information of China (English)

    吴茂铸; 汪官富; 倪淑红; 赵年家; 王芬; 韩子华

    2015-01-01

    Objective To explore the imaging appearances and the value of multi-slice CT (MSCT)with post-processing tech-niques in diagnosis and treatment of lumbar hernia (LH).Methods The imaging and clinical data of 1 6 patients with LH which were confirmed by surgery were analyzed retrospectively.Results In 1 6 patients,1 7 lesions of LH were revealed by MSCT.There were superior lumbar hernias in 13 (76.5%),inferior lumbar hernias in 3 (1 7.6%)and diffuse lumbar hernia in 1 (5.9%).Hernia ring in diameter ranged from 1.5 to 9.3 cm,and the hernia sac size ranged from 1.8 cm×2.4 cm to 1 1.3 cm× 6.2 cm.MSCT showed oval or flask shaped mass of extraperitioneal fat with or without peritoneum and visceral contents protruded through the de-fecting fascia floor into lumbar triangle.Superior lumbar hernia was bounded by the 12th rib superiorly,the erector spine muscle medially and the internal oblique muscle laterally.Inferior lumbar hernia was bounded by latissimus dorsi muscle medially,the ex-ternal oblique muscle laterally and the iliac crest inferiorly.Hernia contents included colon in 3 patients and small bowel in 2 with in-carcerated hernia with small bowel obstruction in 1,and adipose tissue and mesentery in other 12.All patients received surgery treatment,and the appropriate surgical methods were selected according to the MSCT findings.The surgical findings were consistent with MSCT results.No recurrence was found during follow-up.Conclusion LH has characteristic CT manifestations.MSCT volu-metric scanning with post-processing techniques can clearly display the type of LH,the size of abdominal wall defect,hernia contents and their complications.It is helpful for diagnosis of the LH and differentiation from other diseases,which may provide important information for clinical surgery.%目的:探讨腰疝(LH)的多层螺旋 CT(MSCT)表现特征及后处理重建技术在 LH 诊治中的临床价值。方法收集经手术病理证实的 LH 16例,回顾性分析其临

  8. Evaluation of Acute Mesenteric Ischemia with Multi-slice Spiral CT%急性肠缺血的多层螺旋CT诊断

    Institute of Scientific and Technical Information of China (English)

    杨颖; 韩飞; 田笑; 殷小平

    2010-01-01

    目的 探讨多层螺旋CT(MSCT)诊断急性肠缺血(AMI)的诊断价值.方法 对30例临床可疑AMI患者行MSCT检查,进行图像重建,评价肠管缺血的异常征象,并与手术或DSA相对照.结果 急性肠系膜上动脉栓塞(SMAE)4例,肠系膜上动脉血栓形成(SMAT)6例,肠系膜上静脉血栓形成(SMVT )10例,其余10例.其中,SMVT时,肠管扩张、积气、积液9例,系膜根水肿,腹水5例,肠管白色改变4例,SMAT时,肠壁增厚5例.其他征象均见于不同病因、不同程度的肠缺血.结论 MSCT对诊断和鉴别AMI有很高敏感性和特异性.

  9. Creation of individual ideally shaped stents using multi-slice CT: in vitro results from the semi-automatic virtual stent (SAVS) designer.

    Science.gov (United States)

    Hyodoh, Hideki; Katagiri, Yoshimi; Sakai, Toyohiko; Hyodoh, Kazusa; Akiba, Hidenari; Hareyama, Masato

    2005-08-01

    To plan stent-grafting for thoracic aortic aneurysm with complicated morphology, we created a virtual stent-grafting program [Semi Automatic Virtual Stent (SAVS) designer] using three-dimensional CT data. The usefulness of the SAVS designer was evaluated by measurement of transformed anatomical and straight stents. Curved model images (source, multi-planer reconstruction and volume rendering) were created, and a hollow virtual stent was produced by the SAVS designer. A straight Nitinol stent was transformed to match the curved configuration of the virtual stent. The accuracy of the anatomical stent was evaluated by experimental strain phantom studies in comparison with the straight stent. Mean separation length was 0 mm in the anatomical stent [22 mm outer diameter (OD)] and 5 mm in the straight stent (22 mm OD). The straight stent strain voltage was four times that of the anatomical stent at the stent end. The anatomical stent is useful because it fits the curved structure of the aorta and reduces the strain force compared to the straight stent. The SAVS designer can help to design and produce the anatomical stent.

  10. The clinical research of multi-slice spiral CT in intestinal imaging%多层螺旋CT肠道成像的临床研究

    Institute of Scientific and Technical Information of China (English)

    高剑波; 郭华; 耿尚文; 张永高

    2011-01-01

    Objective To investigate the value and usefulness of optimized multislice CT enterography (MSCTE) with orally administered isosmotic mannitol (2. 5%) as negative contrast in demonstrating the small bowel and its abnormality. Methods Forty patients suspected of intestinal tumors were randomly divided into two groups and underwent conventional or optimized MSCTE. The expansion degree of bowel lumen and the thickness of bowel wall were evaluated for the six segments of the small intestine. The other 20 patients suspected of gastrointestinal diseases underwent gastrointestinal CT imaging.The expansion degree of bowel lumen and the wall thickness of bowel wall were statistically analyzed with Chi-Square test and t test. Results The wall thickness of the stomach, ileum and colon were (2. 56 ±0.52) ,(1.41 ±0. 15),(1.46 ±0. 13),(1.91 ±0. 25), (1.97 ±0.26),(2.01 ±0. 19), (2. 04 ±0.24)and (2. 05 ±0. 18)mm. Optimized method was superior to conventional method in the expansion degree of the second and third segments of the small intestine (P < 0. 05) . There was no significant differences between two groups in the expansion degree and depiction of mucosa for the other segments of small intestine (P > 0. 05). The gastrointestinal CT imaging was poor in the depiction of the duodenum and jejunum, but stomach, ileum and colon were fully illustrated. Conclusion Optimized MSCTE was superior to conventional method in demonstrating the small bowel, and gastrointestinal CT imaging can expand diagnostic scope because of good observation of whole gastrointestinal tract.%目的 探讨口服2.5%等渗甘露醇多层螺旋CT肠道成像(MSCTE)的优势及其临床价值.方法 40例临床怀疑为小肠肿瘤疾病者采用完全随机法分为2组,分别行常规法与改良法CT小肠MSCTE,对比2种方法观察6段小肠(1段为十二指肠,2段为空肠近段,3段为空肠远段,4、5、6段为回肠)的管腔扩张度及管壁厚度.20例临床怀疑胃肠道疾病患者

  11. 多层螺旋CT对甲状旁腺腺瘤的诊断价值%The value of multi-slice spiral CT in diagnosis of parathyroid adenoma

    Institute of Scientific and Technical Information of China (English)

    于永慧; 朱吉高; 贾志东; 王立兴; 吴海涛

    2011-01-01

    Objective:To study the value of multi-slice spiral CT (MSCT) in diagnosis of parathyroid adenoma. Methods: Retrospective analysis was performed in clinical data and CT images of 10 cases of parathyroid adenoma proved surgically and pathologically. Results: All of the parathyroid adenomas were originated from the inferior pole of parathyroid gland with 4 cases at the right side and 6 cases at the left side. All located at the recess between trachea and esophagus. The sizes of adenomas ranged from 0. 9 cm× 1. 0 cm~3. 0 cm×8. 0 cm. The tumors were round or oval. Well-demarcated. Iso-attenuated yet higher than that of thyroid gland on plain CT scan. After contrast medium administration, the adenomas revealed enhancement with various degrees but lower than that of thyroid and adjacent blood vessels. 8 cases of adenomas were enhanced homogeneously. 2 cases showed no enhancement in necrosis. Conclusion: The location. Shape. Size. And the relationship with surrounding structures of parathyroid adenoma could be precisely displayed on enhanced MSCT and 3D reconstruction, which is valuable for surgery.%目的:探讨多层螺旋CT(MSCT)对甲状旁腺腺瘤的诊断价值.方法:回顾性分析10例经手术病理证实为甲状旁腺腺瘤的CT及临床资料.结果:10例甲状旁腺腺瘤均起源于下甲状旁腺.右侧4例,左侧6例,均位于气管食管沟内.肿瘤大小约0.9cm×1.0cm~3.0cm×8.0cm.呈圆形或卵圆形,边缘光滑完整.平扫肿瘤呈等密度.较正常甲状腺为低密度.增强后10例肿瘤均有不同程度强化,但均较周围血管密度及正常甲状腺密度低.增强后肿瘤呈均匀强化者8例,坏死不均匀强化者2例.结论:MSCT增强及三维重建检查可准确显示甲状旁腺腺瘤的部位、形态、大小及其与周围结构的关系,对临床手术有重要的指导意义.

  12. The Diagnostic Value and Type of Multi-slice Spiral CT Reconstruction in Small Renal Carcinomas%多层螺旋CT三维重建对小肾癌的诊断及分型

    Institute of Scientific and Technical Information of China (English)

    宋强; 汪秀玲; 胡春峰

    2011-01-01

    Objective:According to the CT scan image and the performance of three-dimensional reconstruction,to study the diagnostic value and type of MSCT reconstruction in small renal carcinomas.Materials and Methods:A retrospective analysis was done for 43 cases of small renal carcinomas which received MSCT examination and confirmed by pathology in our hospital,analysis and type them with their performance in the CT examination.Results:There are 16 cases of small renal carcinoma of protruding type,their performance of CT examination are the tumors convex to the outline of the kidney or convex to the renal pelvis or calyx,when in enhancement CT scan,the contrast agent in the tumor are fast flowing in and fast flowing out which are the performance of malignant tumor;There are 6 cases of small renal carcinoma of inside renal parenchyma type,their performance of CT examination are the tumors limited in the renal parenchyma,when in enhancement CT scan,the performance of the tumor are f the typical performance of malignant tumor;There are 9 cases of small renal carcinoma of cystic type,their performance of CT examination are that when in enhancement CT scan,there are multiple enhanced uneven thickness stripes or small pitchy enhancement in the tumor;There are 5 cases of small renal carcinoma of multiple type,their performance of CT examination are that there are multiple small renal carcinomas in one kidney.Conclusion:Multi-slice spiral CT scan with 3D reconstruction image post-processing techniques can accurately and effectively diagnose various types of small renal carcinoma.%目的:根据CT扫描图像及三维重建表现,探讨多层螺旋CT扫描对小肾癌的诊断及鉴别诊断的价值,并对小肾癌进行分型。资料与方法:收集行多层螺旋CT扫描并经临床病理证实的43例小肾癌病例资料,就其CT表现进行分析并进行分型。结果:凸出型小肾癌23例,CT表现为肿瘤凸向肾轮廓之外或凸向肾盂、肾盏,增强

  13. 膀胱异位嗜铬细胞瘤的MSCT诊断%Multi-slice CT diagnosis of ectopic pheochromocytoma of urinary bladder

    Institute of Scientific and Technical Information of China (English)

    许小伍; 唐永华; 缪飞

    2012-01-01

    Objective To discuss MSCT imaging features of ectopic pheochromocytoma of urinary bladder (EPB). Methods We retrospectively analyzed the imaging features of 8 cases of EPB proved by pathology. Results All lesions were solitary. 3 cases were found in trigone, 1 case in neck. 1 case in right lateral wall, 2 lesions in submucosa, 6 cases muscular layer trigone of urinary bladder, 2 lesions in dome of urinary bladder, 1 lesion in anterior wall of urinary bladder, and 3 lesions in posterior wall of urinary bladder. Low-density without cystic degeneration was found in plain CT scan. Annular calcification was only seen in one case. Obvious enhancement was shown in arterial phase. The difference between arterial phase and plain scan was >40 HU, that between arterial phase and portal phase was about 15 HU. Conclusion Radiology features of EPB in MSCT have characteristics, which can confirm the diagnosis before surgery.%目的 讨论膀胱异位嗜铬细胞瘤MSCT表现.方法 对8例资料完整、经手术证实膀胱异位嗜铬细胞瘤的CT图像进行回顾性分析.结果 8例肿块均为单发,分别位于膀胱三角区(2例)、顶部(2例)、前壁(1例)、后壁(3例),2例位于粘膜下,6例位于膀胱肌层.病灶平扫呈均匀低密度,无囊变,1例可见环形钙化,增强扫描动脉期明显均匀强化,动脉期与平扫病灶CT值相差>40HU,门脉期与动脉期CT值相差为15HU左右.结论 膀胱异位嗜铬细胞瘤在MSCT有其特征性表现,术前可以明确诊断.

  14. Appearance of Multi Slice CT in Congenital Inner Ear Development Malformations%先天性内耳发育畸形的MSCT表现

    Institute of Scientific and Technical Information of China (English)

    蒲俊智; 宋薇; 刘军; 章强; 李小军; 志彦

    2009-01-01

    目的:探讨先天性内耳发育畸形的多层螺旋CT(MSCT)表现和特征.方法:采用GE LightSpeed16排螺旋CT扫描仪,行螺旋扫描,取层厚0.625 mm,Bone Plus骨算法,单侧DFOV 9.6 cm或7.5 cm放大重建,行多平面重建(MPR)和容积再现技术(VR)重建.结果:47例89耳为先天性内耳畸形,其中Michel畸形4例5耳、耳蜗未发育1例1耳、共腔畸形4例6耳、阶间隔Ⅰ型(囊状耳蜗-前庭畸形)1例1耳、耳蜗发育不全Ⅰ型3例4耳、阶间隔Ⅱ型(Mondini畸形)14例24耳、耳蜗发育不全Ⅱ型2例4耳、前庭-半规管畸形5例9耳、前庭导水管扩大29例54耳(其中29耳伴随其他畸形)、内耳道畸形16例26耳(其中21耳伴随其他畸形)、内耳畸形伴颈静脉球高位12例18耳.结论:MSCT检查高分辨图像对先天性内耳骨迷路畸形的诊断、分型以及人工耳蜗植入术的筛查、术后效果评价、随访复查有重要的临床指导意义.是.首选的检查方法.

  15. 回盲部憩室炎MSCT检查的临床价值%Clinical value of multi slice spiral CT examination in assessment of ileocecal intestinal diverticulitis

    Institute of Scientific and Technical Information of China (English)

    李光明; 刘林; 曾军

    2012-01-01

    Objective To explore the value of MSCT in diagnosis of ileocecal diverticulitis. Methods Fifteen patients (9 males. 6 females, aged 42 to 82 years old. with an average of 63. 8 years) were studied retrospectively. All the cases were performed with routine pelvic CT scan, eight cases were performed with enhancement scanning. MPR, including sagittal image, coronal image, parallel ilium image, and vertical ilium image were reconstructed. Results Of 15 cases, 7 wree found in ascending colon. 4 in cecum, 3 in terminal ileum. 1 in appendix and 4 were multiple these were 21 of diverticulitis among all of diverticulum 28. The diverticulum diameter ranged from 5~56 mm an with average of 27 mm. Divcrticulum wall increased thickness in 21. crude in 21; close together intestinal canal increased thickness 9 cases, liquid 19. including gas-liquid 2. fecalith or deformed hyperdense in 9 in the diverticulum; Diverticulum size ranged from 5 ~110 mm. average 27 mm; Diverticulum environment fat inflammatory infiltration was found in 6 cases. Conclusion Ileocecal diverticulitis can be afforded important evidence for diagnosis by applying MSCT examination.%目的 探讨回盲部憩室炎MSCT检查的临床价值.方法 回顾性分析经手术或结肠镜检查证实的15例回盲部憩室炎,其中男9例.女6例,年龄42 ~82岁,平均63.8岁.术前均行常规盆腔CT扫描,8例行增强扫描和扫描后行冠状、矢状、平行髂骨和垂直髂骨四个方向的MPR重建.结果 15例病例中升结肠7例、盲肠4例、回肠末段3例、阑尾1例,其中4例为多发,共28个憩室,21个并发憩室炎;憩室内含液体19个、其中液气平面2个,含粪石或者不成形的高密度影9个;憩室大小5 ~56mm,平均为27mm;憩室壁增厚21个,毛糙21个;相邻肠管壁增厚9例;憩室周围脂肪炎性浸润6例.结论 回盲部憩室炎MSCT检查对明确诊断提供重要的依据.

  16. 多层螺旋CT(MSCT)在异位阑尾炎诊断中的临床价值%Value of Multi-slice Spiral CT in the Diagnosis of Heterotopia Appendicitis

    Institute of Scientific and Technical Information of China (English)

    裴守科

    2015-01-01

    目的探讨MSCT (多层螺旋CT)超薄层扫描和后处理技术在异位阑尾炎诊断中的临床价值。方法18例异位阑尾炎患者行MSCT,并经计算机后处理工作站行多平面重组(Multiplanar reconstruction,MPR)、曲面重组(Curved planar reformation,CPR),回顾性分析其类型,对异位阑尾炎CT表现进行分析、总结,并与手术及病理结果对照。结果18例患者中高位肝下阑尾5例,低位阑尾7例,盲肠后腹膜外阑尾(腰部阑尾)2例,左下腹位阑尾4例。结论 MSCT超薄层扫描及后处理技术可以多方位显示异位阑尾解剖关系及病变周边情况,提高对异位阑尾炎术前诊断准确率。%Objective To evaluate the clinical value of Multi-slice spiral CT (MSCT) in the diagnosis of Heterotopia Appendicitis. Methods 18 patients with Heterotopia Appendicitis underwent preoperative contrast-enhanced MSCT.Images were transfer ed to the workstation and then processed with multiplanar reconstruction (MPR),curved planar reformation (CPR).CT manifestations were analysed and compared with surgical and pathological findings. Results 18 patients with Heterotopia Appendicitis , 5 have under liver high Appendix ,and 7 have low Appendix, 2 for waist Appendix, and 4 for the bot om left of abdomen Appendix. Conclusion MSCT and MPR/CPR can provide an advantage of showing the appendix multi-directional y that can improve the diagnosis accuracy of Heterotopia Appendicitis .

  17. MSCT和MRI对浸润性宫颈癌术前分期的价值对比%Comparison of multi-slice spiral CT and MRI in the diagnosis of pre-surgicai staging of invasive cervical cancer

    Institute of Scientific and Technical Information of China (English)

    邱书珺; 陆晓兰; 蒋小平; 王家强; 顾倩

    2012-01-01

    目的:对比浸润性宫颈癌在MSCT和MRI上表现差异及术前分期价值.方法:搜集有手术病理结果证实的宫颈癌82例,术前行CT检查74例,行MRI检查63例,以术后病理分期为标准,计算并比较CT、MRI对不同期宫颈癌的诊断符合率;对比分析两组图像上肿瘤大小、阴道或穹窿侵犯、宫体侵犯以及宫旁侵犯,分别计算并比较诊断符合率、敏感度及特异度.结果:对≤Ⅰ B1期宫颈癌,CT和MRI诊断符合率分别为47.56%、70.73%,Ⅰ B2~ⅡA期分别为80.49%、87.80%,≥ⅡB期分别为91.46%、82.93%.在显示肿瘤方面,MRI对≤4cm癌肿、阴道或穹窿侵犯方面的显示优于CT;CT对宫体侵犯诊断灵敏度高,对盆腔转移淋巴结的诊断优于MRI.结论:对≤Ⅰ B1和Ⅰ B2~ⅡA的早中期浸润性宫颈癌术前行MRI检查更有价值;而对于≥ⅡB的晚期浸润性宫颈癌行MSCT检查则更具有价值.%Objective:To retrospectively evaluate the significance of MRI and multi-slice Spiral CT (MSCT) for pre-treatment staging of invasive cervical cancer. Methods:82 patients with biopsy-proven cervical cancer were enrolled in this study. 74 patients underwent CT and 63 underwent MRI before surgery. Using surgicopathologic findings as the reference standard, to compare the accuracy of CT and MRI in various stages of cervical cancer, Tumor size, infiltration of vagina or fornix,corpus and parametrium involvement found in these 2 groups were compared and analysed,and the sensitivity,specificity and accuracy were calculated. Results:For stage ≤I Bl ,the diagnostic accuracy was 47. 56% for CT and 70. 73% for MRI; for stage I B2 ~ H A, the accuracy was 80. 49% and 87. 80% respectively; for advanced stage (≤ II B),it was 91. 46% and 82. 93% respectively. MRI was superior to CT for delineating cervical carcinoma with the size smaller than 4. 0cm and infiltration of vagina or fornix. CT is superior to MRI for the diagnosis of pelvic lymph node

  18. Clinical Significance of Multi - slice CT in Diagnosis of Thyroid Nodules with Calcification%多层螺旋CT诊断钙化性甲状腺结节的临床意义

    Institute of Scientific and Technical Information of China (English)

    于军

    2012-01-01

    Objective To investigate the clinical significance of features of thyroid nodule with calcification in diagnosis and differential diagnosis of benign and malignant thyroid nodules. Methods We retrospectively analyzed the pathologic results and multi - slice CT (MSCT) signs of 77 cases of thyroid nodules. Results The detection rate of thyroid nodules with calcification in MSCT imaging was 21.60% (35/162), the detection rate of benign nodules was 15.45% (19/123) which was significantly lower than 41.03% (16/39) of malignant nodules. The thyroid calcification ratio of bulky- calcification in benign nodules was higher than that of malignant nodules, while micro - calcification in malignant nodules was higher than that in benign nodules (P<0.05). But there was no significant correlation between the number of calcification and malignant nodules. Conclusions Thyroid nodules with calcification especially micro- calcification is considered to be the important sign of thyroid carcinoma.%目的 探讨甲状腺结节的钙化特点对其良恶性诊断与鉴别诊断中的临床意义.方法 对137例经病理和多层螺旋CT(MSCT)检查证实的甲状腺结节的临床资料进行回顾性分析.结果 甲状腺结节MSCT的钙化检出率为21.60% (35/162),良性结节为15.45%(19/123),显著低于癌性结节的41.03% (16/39);良性钙化粗大钙化的发生率显著高于恶性结节,而良性结节微小钙化的发生率显著低于恶性结节(P<0.05),但钙化灶数目与甲状腺恶性结节无显著性关系.结论 甲状腺结节伴有钙化尤其是微小钙化灶是诊断甲状腺癌的重要征象.

  19. The diagnostic value of VR techniques of multi-slice spiral CT in the pulmonary sequestration%多层螺旋CT容积再现对肺隔离症的应用价值

    Institute of Scientific and Technical Information of China (English)

    刘玉芳

    2012-01-01

    Objective To evaluate the diagnostic value of VR techniques with multi - slice spiral CT in the pulmonary sequestration. Methods MSCT angiography were performed and reconstructed imaging VR in 11 patients with surgically confirmed pulmonary se-questration( PS ), The emphasis was shown the relationship between abnormal vessels and lesions. Results Among 11 cases PS,the lesion was located at the left lower lobe in 7 and at the right lower lobe in 4 cases, abnormal supplying arteries were from the thoracic aorta. On plain CT scan images,the mass-like lesions were found in 6 cases,irregular shape lesions in 5 cases. On VR images clearly displayed abnormal supplying arteries from systemic arteries in all patients. Conclusion MSCT angiographytechnology can accurately and directly display the blood - supply of the segregation tissue. So this method is very important value in PS.%目的 研究多层螺旋CT容积对肺隔离症的应用价值.方法 对经外科手术及病理证实的11例肺隔离症患者多层螺旋CT血管造影,利用容积再现(VR)技术,分析异常血管与病灶的关系.结果 11例患者中,7例病灶位于左下叶,4例病灶位于右下叶,异常供血全部来自胸主动脉.MSCT平扫表现为囊实性肿块6例,其他不规则形5例.VR重组技术中11例能明确显示异常体动脉供血及肺内血管网.结论 多层螺旋CT血管造影及结合容积再现重组技术能直观显示肺隔离症的异常体动脉供血及肺内血管网,具有重要的临床应用价值.

  20. Diagnostic value of multi-slice CT in solitary fibrous tumor of the pleura%多层螺旋CT对胸部孤立性纤维瘤的诊断价值

    Institute of Scientific and Technical Information of China (English)

    李会菊; 李晓阳; 邢国凤; 张德江; 付敬华

    2015-01-01

    Objective To explore the value of multi-slice CT in the diagnosis of solitary fibrous tumor of the pleura (SFTP). Methods The clinical symptoms and CT imaging features of 8 patients clinically and pathologically diagnosed as SFTP were retrospectively analyzed, which were compared with histopathological results. Results All the lesions of the 8 patients were located in dirty pleura. CT-scan showed 6 cases of mass boundary finishing, 1 case of lobulated rim, 1 case of irregular shape, 5 cases of uniform density, and 3 cases with low density area in mass center. Six patients underwent contrast-enhanced CT, of which 4 showed non-uniform reinforcement and 2 showed uniform reinforcement, including 3 cases of tumors with enhancement of blood vessels. Pathological examination showed that the tumor was composed of spindle cells, with a number of arrangements:immunohistochemical Vimentin (+) in 7 cas-es, CD34 (+) in 8 cases, the bcl-2 positive (+) in 8 cases, Sl00 (-) in 7 cases. Conclusion SFTP patients have certain characteristic CT manifestations. CT examination has a certain value for SFTP positioning and the relationship be-tween tumor and surrounding tissue structure.%目的:探讨多层螺旋CT对胸部孤立性纤维瘤(SFTP)的诊断价值。方法回顾性分析经临床和肿瘤病理学确诊的8例SFTP患者的临床症状、螺旋CT影像特点,并与组织病理学结果进行对照。结果所有8例患者病变均位于脏层胸膜,CT平扫显示6例肿块边界光整,1例边缘呈分叶状,1例呈不规则形状;5例密度较均匀,3例肿块中心有低密度区。6例行对比增强后4例不均匀强化,2例强化均匀,其中3例肿块内出现增强的血管。病理学检查显示,肿瘤由梭形细胞构成,有多种排列方式;免疫组化Vimentin(+)7例、CD34(+)8例、bcl-2阳性(+)8例,Sl00(-)7例。结论 SFTP患者的CT表现具有一定的特征性,CT检查对SFTP的定位以及明确肿瘤与周围组织结构的关系有一定价值。

  1. 28例儿童漏斗胸术前多层螺旋CT的诊断与评估%Preoperative diagnosis and assessment of 28 children with pectus excavatum Multi-Slice CT

    Institute of Scientific and Technical Information of China (English)

    白林; 彭泽华; 梁洪; 高燕

    2012-01-01

    Objective To evaluate the preoperative diagnosis of multi-slice CT (MSCT) in children with pectus excavatum. Methods We retrospectively analyzed 28 cases of funnel chest diagnosed by MSCT examination. All the cases were divided into three groups with pathogenetic condition in mild, moderate, serious degree respectively according to the depression of the chest diagnosed by CT. We measured the degree of sternal depression, CT depression index, the angle of sternal depression, cardiac rotation angle, Haller index,compare those five indicators among the three groups,and analyzed the correlation between cardiac rotation angle and the other four indices. Results Varying degrees of pectus excavatum were found in the 28 cases including 14 cases of mild depression,9 cases of moderrate depression, and 5 cases of serious depression. The five indicators between each of the two groups were significantly different ( P < 0.01). Cardiac rotation angle was positively correlated to sternal depression depth, CT depression index and Haller index ( rs = 0. 736,0. 873,0. 881 ,P < 0.01) ,and was negative correlated to sternal depression angle (rt = -0.731 ,P < 0.01). Conclusion MSCT can accurately display the deformity of funnel chest and the rotation of cardiac compression, to provide effective help for clinical treatment.%目的 评价多层螺旋CT(MSCT)在儿童漏斗胸术前诊断中的价值.方法 回顾性分析28例经MSCT检查并诊断为漏斗胸患儿的CT资料,根据CT凹陷指数,将其分为轻、中、重度三组,测量并比较三组患儿胸骨凹陷深度、CT凹陷指数、胸骨凹陷角度、心脏旋转角度及Haller指数五项指标的差异,分析心脏旋转角与其它四项指标的相关性.结果 ①28例均有不同程度胸骨凹陷,其中轻度凹陷14例,中度凹陷9例,重度凹陷5例;②胸骨凹陷深度、CT凹陷指数、胸骨凹陷角度、心脏旋转角度及Haller指数五项指标在轻、中、重度三组间差异均有统计学

  2. 多排螺旋CT后处理技术在胆源性胆囊-十二指肠瘘诊断中的应用%Multi-slice CT in diagnosing cholecysto-duodenal fistula

    Institute of Scientific and Technical Information of China (English)

    王均庆; 陆风旗; 张雷; 张追阳; 丁忠; 余迅

    2015-01-01

    目的 应用多排螺旋CT(MSCT)后处理技术分析胆源性胆囊-十二指肠瘘的典型影像学特征,探讨其临床价值.方法 回顾性分析2011年1月到2015年7月南京医科大学附属第二医院收治的33例胆源性胆囊-十二指肠瘘患者资料,所有患者均行MSCT平扫及增强检查,用CT后处理技术分析其影像学特征性改变.结果 33例患者胆源性胆囊-十二指肠瘘发生部位:十二指肠球部15例(45.5%),十二指肠球降部3例(9.1%),降部10例(30.3%),水平部5例(15.1%).胆源性胆囊-十二指肠瘘直接征象:瘘道清楚显示,部分呈哑铃型,共有16例显示了瘘道.胆源性胆囊-十二指肠瘘间接征象:2例胆囊显示不清,1例因胆囊癌体积增大,1例因急性胆囊炎胆囊增大;29例胆囊体积明显缩小,体积为6 cm×2 cm~2 cm×1 cm;胆囊壁增厚,平均厚度5 cm;胆囊与十二指肠粘连,分解不清,胆囊周围结构紊乱,可见积液.26例胆道系统积气,其中胆囊积气22例次,胆管积气19例次;胆道系统结石26例次,胆囊结石22例次,胆囊颈部结石6例次,胆总管结石13例次,肝内外胆管结石1例次.十二指肠与胆囊粘连处见憩室样征改变,11例十二指肠出现憩室样征.胆源性胆囊-十二指肠瘘并发症:5例胆石性肠梗阻,2例肝多发脓肿.结论 多层螺旋CT扫描及后处理技术的应用不但可有效显示胆源性胆囊-十二指肠瘘的部位、有无瘘道及形态、胆囊形态、胆囊及胆管积气、结石及周围情况,还可充分显示其并发症,对手术方案的制定有指导意义,具有较高的临床应用价值.%Objective To study the radiologic features and the diagnostic value of multi-slice spiral CT (Multi-slice CT, MSCT) in cholecysto-duodenal fistula.Methods A retrospective analysis was conducted on 33 patients with cholecysto-duodenum fistula.Plain and IV enhanced MSCT were carried out on these patients.Results Of the 33 patients, the fistula was located at

  3. 肝细胞癌合并近端肝动脉-门静脉分流的多层螺旋CT诊断及临床意义%Diagnosis and clinical significance of multi-slice spiral CT in hepatocellular carcinoma combined with proximal hepatic artery portal vein shunt

    Institute of Scientific and Technical Information of China (English)

    王长河

    2015-01-01

    目的 探讨多层螺旋CT在肝细胞癌(HCC)合并近端肝动脉-门静脉分流(APS)中的临床诊断价值和意义.方法 选取驻马店市中心医院收治的84例肝细胞癌患者作为研究对象,对其分别进行多层螺旋CT及肝动脉数字减影血管造影(DSA)检查,对两种方法的临床诊断准确性进行观察比较,并以DSA诊断近端APS为标准,对多层螺旋CT诊断的CT表现特征进行对比分析.结果 经DSA检查,65例患者检查出合并近端APS,占77.4%,经多层螺旋CT检查,57例检测出合并近端APS,占67.9%,多层螺旋CT与DSA两种检查方式对比临床诊断准确性差异未见统计学意义(P>0.05).多层螺旋CT对于周围型肝APS的检出率明显高于DSA检查,组间检测情况差异有统计学意义(P<0.05).结论 肝细胞癌合并近端肝动脉-门静脉分流经多层螺旋CT检查诊断的准确性可与DSA相比,其对肝癌临床治疗具有重要指导意义.%Objective To evaluate the clinical diagnostic value and clinical significance of multi-slice spiral CT in hepatocellular carcinoma (HCC) combined with proximal arterioportal shunt (APS).Methods Eighty-four cases of hepatocellular carcinoma in our hospital were selected as the research objects,and were given the multi-slice spiral CT and hepatic arterial digital subtraction angiography (DSA) examination.The diagnostic accuracy of the two methods were observed and compared.DSA diagnosis of proximal APS as the standard,CT features of multi-slice spiral CT were andyzed and compared.Results Sixty-five patients had combined with proximal APS,accounting for 77.4% through the DSA examination.Fifty-seven cases were detected with proximal APS,accounting for 67.9% through the multi slice spiral CT examination.No significant difference between the two kinds of inspection methods of comparative clinical diagnostic accuracy (P > 0.05).The detection rate of multi slice spiral CT for peripheral hepatic APS was significantly higher

  4. 鼻咽癌多层螺旋CT灌注输入动脉的选择%Selection of reference arteries with multi-slice spiral CT perfusion imaging in diagnosis of nasopharyngeal carcinoma

    Institute of Scientific and Technical Information of China (English)

    丁玲; 苏丹柯; 刘丽东; 金观桥; 赵梦鸥

    2011-01-01

    目的 分析不同输入动脉所得鼻咽癌(NPC)多层螺旋CT灌注参数值的差异.方法 对38例经病理确诊的初发NPC患者进行CT灌注扫描,每例患者均分别选择肿瘤同侧的颈内动脉(ICA组)和颈外动脉(ECA组)作为输入动脉、颈内静脉作为输出静脉进行灌注成像后处理,获得两组灌注参数.采用配对t检验分析两组灌注参数值的差异,并对两组数据进行直线相关分析.结果 两组不同血管所得灌注参数值差异均无统计学意义(P>0.05),两组数据血流量、血容量、平均通过时间和表面通透性的相关系数分别为0.879、0.630、0.525、0.695(P均<0.001),两组血管所得数据均成正相关.结论 在对NPC患者进行CT灌注成像后处理时,可根据患者血管的显示情况选择颈内动脉和(或)颈外动脉作为输入动脉.%Objective To observe the difference of multi-slice spiral CT perfusion parameters in different reference arteries in diagnosis of nasopharyngeal carcinoma (NPC). Methods Thirty-eight patients with NPC underwent CT perfusion imaging, internal carotid artery (ICA group) and external carotid artery (ECA group) were selected respectively as reference artery with CT perfusion imaging post-processing in each patient. The differences of perfusion parameters between the two groups were analyzed with paired-samples t test and linear correlation. Results Parameters derived from ICA and ECA as reference artery were not statistically different (all P>0. 05). There were positive correlation of all parameters between both groups, the correlation coefficients was 0. 879 for blood flow, 0. 630 for blood volume, 0. 525 for mean transit time and 0. 695 for permeability surface (all P<0. 001). Conclusion On the post-processing of CT perfusion imaging for NPC,internal carotid artery and external carotid arteries can both be selected as the reference artery according to their displaying.

  5. Multi-slice spiral CT perfusion imaging of chronic obstructive pulmonary disease%多层螺旋CT灌注成像对慢性阻塞性肺疾病的诊断价值

    Institute of Scientific and Technical Information of China (English)

    邵燕惠; 钱农; 薛跃君; 戴伊红

    2008-01-01

    目的 研究CT灌注成像对慢性阻塞性肺疾病(COPD)的诊断价值.方法 20例COPD患者和20例志愿者行8层螺旋CT灌注成像,采用电影扫描(cine)方式,层厚5 mm,扫描时间0.5 s/层,注射对比剂后延时5 s,总扫描时间为45 s,测量感兴趣区血流量、血容量、平均通过时间及表面通透性和时间-密度曲线.结果 COPD患者的时间-密度曲线较志愿者曲线平坦,峰值明显降低.COPD患者血流量[(24.77±11.49)ml·min-1·100 g-1]、血容量[(2.48±1.02)ml/100 g]及表面通透性[(2.75±1.13)ml·min-1·100 g-1]明显低于志愿者[血流量(290.14±107.59)ml·min-1·100 g-1、血容量(16.51±5.98)ml/100 g、表面通透性(8.80±3.03)ml·min-1·100 g-1];平均通过时间[(10.58±4.85)s]高于志愿者[(4.50±1.71)s],差异均具有统计学意义(P<0.01).结论 多层螺旋CT肺灌注扫描对COPD的诊断有一定的辅助作用.%Objective To evaluate the diagnostic value of multi-slice spiral CT(MSCT)perfusion imaging in chronic obstructive pulmonary disease(COPD).Methods Twenty COPD patients and20 volunteers underwent 8-row detector spiral CT(MSCT)perfusion imaging using cine scan mode with5 mm slice thickness.0.5 s rotation time and a total scan time of 45 s with 5 s intervals.60 ml contrast agent(300 mg I/ml)were administered at a rate of 4 ml/s from the forearm superficial vein.The imaging data were transferred to a workstation.A time-density curve and pseudo-color map were generated automatically with GE CT perfusion 3 software,the blood flow(BF),blood volume(BV),mean transit time(MTr)and permeability surface(PS)were measured.Results Time-density curve was flatter and the peak of the curve was obviously lower in COPD patients than the volunteers.The BF.BV.PS in COPD volunteers was(10.58 ±4.85)s and(4.50 ±1.71)s respectively.The BF,BV and PS in COPD patients Was lower than the volunteers,the MTY was higher(P<0.01).Conclusion MSCT perfusion imaging is helpful for the diagnosis of COPD.

  6. 多排CT对肾结石并肾盂恶性肿瘤的诊断价值%Value of Multi-slice CT for the Diagnosis of Kidney Calculi with Renal Pelvis Malignant Tumor

    Institute of Scientific and Technical Information of China (English)

    易志军; 刘建滨; 范立新; 谢安; 郑海军; 王诗斌; 彭国洪

    2012-01-01

    [Objective] To explore the CT diagnosis and the reason of missed diagnosis of kidney calculi with renal pelvis malignant tumor. [Methods] The CT data of 9 cases of kidney calculi with renal pelvis malignant tumor confirmed by pathology were analyzed retrospectively. The site of pathogenesis, histological type, metastasis, complication and the relation with the surrounding tissue were observed. [Results] Among 9 cases of kidney calculi with renal pelvis malignant tumor, 5 cases were transitional cell carcinoma, 3 cases were squamous cell carcinoma and 1 case was adenocarcinoma. Retroperitoneal lymph node metastasis was found in 5 cases including one case of adenocarcinoma and one case of transitional cell carcinoma involving the metastasis of renal capsule and adjacent adipose tissue, liver and adrenal gland. Seven cases were combined with the inflammation of renal pelvis and ureter or pyonephrosis. Three cases were combined with inflammatory granulation of renal pelvis. Two cases of transitional cell carcinoma and one case of cases of squamous cell carcinoma were misdiagnosed as kidney calculi with hydronephrosis infection. The definite diagnosis rate was 66. 7% (6/9) and the misdiagnosis rate was 33. 3% (3/9). [Conclusion] Multi-slice CT for kidney calculi with renal pelvis malignant tumor has higher diagnostic value. However, kidney calculi with renal pelvis accompanied by other lesions are easy to be misdiagnosed.%[目的]探讨肾结石并肾盂恶性肿瘤的CT诊断和漏诊原因.[方法]回顾性分析经手术病理证实的9例肾结石并肾盂恶性肿瘤的CT资料,重点观察肾结石并肾盂恶性肿瘤的发生部位、病理类型、有无转移、合并症及与周围组织关系.[结果]9例肾结石并肾盂恶性肿瘤患者5例为肾盂移行细胞癌,3例为肾盂鳞癌,1例腺癌;5例有腹膜后淋巴结转移,鳞癌、移行细胞癌各1例,累及肾被膜及邻近脂肪组织及肝、肾上腺等多处转移;7例合并肾盂、

  7. 多层螺旋CT在肠道Crohn病诊断中的应用价值%The Value of Multi-slice Spiral CT Enterography in Diagnosing Crohn's Disease

    Institute of Scientific and Technical Information of China (English)

    杨春; 姚倩东; 郑敏文

    2013-01-01

    Objective To investigate the value of multi-slice spiral CT (MSCT) enterography in diagnosing Crohn 's disease (CD). Methods The manifestations on routine CT enterography of 41 patients diagnosed to have CD with comprehensive methods between February 2009 and February 2012 were analyzed retrospectively, including location of the involved bowel segment, thickness of bowel wall and degree of contrast enhancement of the bowel wall as well as the existence of complications. Results Among the 41 cases, there were 36 (87.8%) of skip lesions, 16 (39.0%) of lesions limited to the small intestine, 23 (56.2%) of lesions involving both small intestine and colon, 2 (4.8%) of lesions limited to the colon, 36 (87.8%) of lesions involving the terminal ileum, and 22 (53.7%) of lesions involving cecum or ascending colon. The findings of those patients on MSCT were 41 cases (100%) of bowel wall thickening and mural hyperenhancement, 28 cases (68.3%) of mural stratification, 23 cases (56.1%) of fibrofatty proliferation or para-bowel phlegmon, 16 cases (39.0%) of increased mesenteric vascularity (comb sign), 20 cases of mesenteric lymphadenopathy, 6 cases of incomplete bowel obstruction, and 1 case of fistula. Conclusions MSCT can demonstrate lesions of the small intestine and the colon simultaneously, and it proves to have advantages in depicting mural abnormalities and evaluating extramural abnormalities and activity of CD. Thus, MSCT is helpful in evaluating the course of CD and guiding clinical treatment.%目的 探讨多层螺旋CT (MSCT)在肠道Crohn病(CD)诊断中的应用价值.方法 回顾性分析2009年2月-2012年2月经综合方法确诊为CD的41例患者的MSCT表现,分析病变肠管的部位、肠壁的厚度和增强后病变肠壁的强化程度及并发症.结果 41例中,患病肠段多节段性受累36例(87.8%),单独小肠受累16例(39.0%),小肠和结肠同时受累23例(56.2%),单独结肠受累2例(4.8%),回肠末段受累36例(87.8

  8. Correlative Study between Multi-slice CT Perfusion Imaging and Molecular Pathology in Renal Cell Carcinoma%肾细胞癌MSCT灌注成像与分子病理学的相关性研究

    Institute of Scientific and Technical Information of China (English)

    相成; 丰长申; 徐锐; 朱甲峰

    2010-01-01

    目的 运用多层螺旋CT(MSCT)获取肾癌灌注图像,并与其分子病理学特征相对照,探讨MSCT灌注成像在肾癌诊断和鉴别诊断中的临床应用价值.方法 对42例疑有肾肿瘤的患者行MSC灌注扫描,获得伪彩色的血流灌注参数图,包括血流量(BF)、血容量(BV)、表面通透性(PS)及平均通过时间(MTT)图.在瘤体及瘤旁正常肾皮质选取感兴趣区并记录相应的各项参数值.所有患者均经手术病理证实.采用免疫组化方法(SP法)检测肾肿瘤中血管内皮生长因子(VEGF)的表达及微血管密度(MVD).结果 肾细胞癌的BF、BV和PS值均明显低于正常肾皮质,且Ⅲ级肾癌与Ⅰ、Ⅱ级相比,其BF、BV和PS值明显增高.肾癌的BF、BV、PS值与其VEGF平均光密度值呈正相关(P<0.05),MTT值与VEGF平均光密度值呈负相关(P<0.05).肾癌的MVD值与VEGF值呈正相关(P<0.05).结论 MSCT灌注成像能定量评价肿瘤血管生成、血流灌注及血管通透性改变,有助于肾细胞癌的术前分级,并在肾癌的定性诊断和鉴别诊断方面有一定临床应用价值.%Objective To study the correlation of the perfusion CT parameters and the molecular pathology characteristics of the renal cell carcinoma( RCC ),and to discuss the value of multi-slice CT(MSCT) perfusion imaging in the diagnosis and differential diagnosis of RCC.Methods 42 patients with clinically suspected renal tumors underwent MSCT perfusion imaging.The maps of renal blood volume (BV),blood flow (BF),permeability surface (PS)and mean transit time (MTT)were obtained.Regions of interest (ROI)were drawn within the tumor and the region of normal area adjacent to the tumor.All of the tumors were proved by surgery and pathology withRCC ( n = 42 ).Vascular endothelial growth factor (VEGF) expression and micro-vascular density (MVD) were measured with immuno-histology chemistry technique( SP technique).Results Of the 42RCC,the mean BF,BV and PS value were obviously lower

  9. Study on Blood Perfusion of Normal Femur Heads Epiphyses in Piglets by Multi-Slice CT Perfusion%正常乳猪股骨头骨骺的MSCT灌注研究

    Institute of Scientific and Technical Information of China (English)

    黄春元; 罗帝林; 赵志清; 许朝璇; 梁焕莲; 吴冬; 冯登殿

    2011-01-01

    Objective To evaluate the blood perfusion of epiphyses, physis and metaphysis in normal femur heads of piglets by using multi-slice CT perfusion techniques. Methods Fifty five piglets(2 weeks old) were scanned by MSCT perfusion. The data of creating dynamic picture were analyzed, and the dynamic pictures of 26 femur heads were obtained completely. Every parameters including blood flow(BF) ,blood volume(BV) ,mean transit time(MTT) and time to peak(TTP) were analyzed,and compared with the histological findings. Results The BF of physis was higher than that of epiphysis( P <0.05 ). The BV of metaphysis was the highest in all anatomic regions( P <0.05). The MTT of epiphysis was the longest( P <0.05). There was no significant difference in MTT between physis and metaphysis( P >0.05 ). The TTP of physis was the shortest( P <0.05 ) ,and the other two were the same. CT perfusion imaging coincided with the histological results of the locations and concentrations of blood vessels in epiphyses,physis and metaphysis. Conclusion MSCT perfusion images can demonstrate the perfusion features in the various anatomic regions of femur heads.%目的 运用多层螺旋CT灌注技术评价正常乳猪股骨头骨骺、骺板软骨、干骺端等不同解剖区域的血液供应特征.方法 对15只2周龄的健康乳猪进行多层螺旋CT电影模式灌注扫描,对生成的动态图像数据进行测量分析,共获得26个股骨头的完整图像资料,统计并比较血流量(BF)、血容量(BV)、平均通过时间(MTT)、对比剂到达峰值时间(TTP),并与相应组织学表现进行时照.结果 骺板软骨的BF比骨骺的BF有明显增高(P0.05).各解剖区域中骺板软骨的TTP最短(P<0.05),骨骺与干骺端的TTP基本相同.组织学发现骨骺、骺板软骨、干骺端的血管密度分布特征与相应部位的CT增强率所提示的血供状态基本吻合.结论 多层螺旋CT灌注能够显示股骨头不同解剖区域的血液灌注特征.

  10. The Analysis of 8 Missed Diagnosis of Rib Fracture by Multi-slice CT%多层螺旋CT诊断肋骨骨折8例漏诊分析

    Institute of Scientific and Technical Information of China (English)

    冯莹印; 王浩; 纪盛章

    2012-01-01

    目的 通过回顾性分析2007年以来8例肋骨CT检查漏诊病例,探讨多层螺旋CT诊断肋骨骨折的限度.资料和方法 2007年1月至2011年9月127例行肋骨CT检查患者,男83例,女44例,年龄18-88岁,平均51.83岁.应用TOSHIBA AQUILION 16层螺旋CT或GE Lightspeed 64层VCT行肋骨CT扫描,扫描数据传至工作站,应用多平面重组(multiplanar reconstruction,MPR)、曲面重组(curved planar reformation,CPR)、容积再现(volumerendering,VR)、电影显示等方法观察骨折情况.结果 127例患者中,共检出骨折患者115例,骨折5 65处.1 4例复查患者中,6例骨折情况无变化.另有8例可见原未显示的新骨折,共检出14处.结论 虽然MSCT作为诊断肋骨骨折的必要检查手段有重要意义,但是它存在一定的局限性.因此,我们对可能发生的“隐匿性骨折”病例应提示必要复查,避免医疗纠纷发生.%Objective To investigate the limitation of diagnosing rib fracture by multi-slice CT(MSCT)through retrospective analysis of 8 missed diagnosis of rib fracture since 2007. Methods 127 patients from Jan.2007 to Sep.2011,83 male and 44 female, the scope of age from 18 to 88,the average age was 51.83 years old.Applied TOSHIBA AQUILION 16-Slice Spiral CT or GE Lightspeed 64-Slice VCT for scanning .scanning data transferred to workstation. Observed ribs by MPR, CPR, VR and film visualizing method. Results Of the 127 patients, 115 patients were found 565 fractures.Among the 14 patients of reexamination, 6 patients had no discrepancy and 8 patients had total 14 new fractures which were not found in the first diagnosis. Conclusion MSCT examination is a important method for diagnosing rib fracture, but it have some limitations. So, patients who maybe have occult fracture should be known that reexamination is necessary,in order to avoid medical disputes.

  11. 多层螺旋 CT 小肠造影在诊断肠结核与克罗恩病中的价值研究%Diagnostic value of multi-slice CT enterography in Crohn’s disease and intestinal tuberculosis

    Institute of Scientific and Technical Information of China (English)

    徐莹; 余晨; 陈业媛; 肖香佐; 龚洪翰

    2015-01-01

    Objective To investigate the application value of multi-slice CT enterography (MSCTE)in diagnosing intestinal tuberculosis (ITB)and Crohn’s disease (CD).Methods MSCTE findings were retrospectively analyzed in 25 patients with ITB and in other 25 patients with CD diagnosed through endoscopy,pathologic examination and clinical follow-up.Statistical analysis was performed to find out the difference in CT findings between the ITB and CD.Results 25 patients with CD included the involved ileum in 23,involved duode-num and jejunum in 8,multiple segmental lesions in 20,asymmetrically thickened intestinal wall in 20,hierarchical reinforcement in 1 9,mesenteric vascular hyperplasia in 20,fibrofatty hyperplasia in 18,peritoneal abscess or fistula in 8,anal fistula in 1,and pseu-do-diverticulum formation in the intestinal wall on the opposite side of the mesentery in 2.Meanwhile,the other 25 patients with ITB included the involved terminal ileum in 25,symmetrically thickened intestinal wall in 23,annular enhancement of lymph nodes in 11,thickened peritoneum and omentum together with distinct enhancement,or intestinal adhesion,or ascites appeared in 15.The CD was more likely to represent multiple segmental lesions,asymmetrically thickened intestinal wall,hierarchical reinforcement,mesenteric vascular hyperplasia,fibrofatty hyperplasia,and peritoneal abscess or fistula formation (P <0.05).Meanwhile,the ITB was more likely to represent the lesion only in ileum,symmetrically thickened intestinal wall,and annular enhancement of lymph nodes (P <0.05).Conclusion MSCTE shows promising clinical application in diagnosis and differential diagnosis of CD and ITB.%目的:探讨多层螺旋 CT 小肠造影(MSCTE)在肠结核(ITB)、克罗恩病(CD)诊断中的应用价值。方法回顾性分析经内镜、病理或临床随访证实的 ITB、CD 各25例的 MSCTE 影像表现,并对两者间的差异进行统计学分析。结果25例 CD 中,病变累及回肠23

  12. Diagnostic Value of Non-segmental Misty Mesentery on Multi-slice CT%多层螺旋CT弥漫性肠系膜混浊征的诊断价值

    Institute of Scientific and Technical Information of China (English)

    符熙; 靳仓正; 姚吕祥; 李春芳; 谭婉嫦

    2013-01-01

    Purpose To investigate the value of non-segmental misty mesentery (NMM) in the diagnosis of different diseases on the multi-slice CT (MSCT),and to improve the diagnostic level.Materials and Methods Eighty patients displayed as NMM on CT and proved by pathology or follow-up were selected,including 25 cases of portal hypertension (PH),20 cases of non tuberculous peritonitis,15 cases of tuberculous peritonitis (TBP)and 20 cases of carcinomatous peritonitis (CP).The characteristics of NMM caused by different diseases were compared.Results Of 80 patients with NMM caused by different diseases,PH was easily displayed as grade Ⅰ NMM,acute pancreatitis often had prerenal fascial thickening,and TBP easily lead to high density (>20 Hu) MM.CP was more vulnerable to show grade Ⅲ NMM,parietal peritoneum mass and abdominal mass.There were 21 patients of PH with grade Ⅰ NMM,18 patients (85.71%) were more likely to occur in the mesenteric root.Intestinal wall thickening was seen at the ascending colon in 2patients with PH.There were 11 patients of CP displayed as perietal peritoneum tumor,7 patients (7/11,63.64%) in the right lower abdomen,2 (2/11,18.18%) in the anterior peritoneum and 2 (2/11,18.18%) around the parietal peritoneum.There were 9 patients of CP showed abdominal mass,5 (5/9,55.56%) were found in the right lower abdomen,2(2/9,22.22%) in the anterior lower abdomen,and 2 (2/9,22.22%) showed multiple lesions in the peritoneal cavity.Conclusion NMM can be caused by different reasons.Combined with other CT findings and clinical history would be helpful to make the correct diagnosis.%目的 探讨不同性质病变所致弥漫性肠系膜混浊征(NMM)的多层螺旋CT (MSCT)诊断价值,提高疾病的诊断水平.资料与方法 80例经手术病理或随访证实的非创伤、代谢类疾病患者,CT均表现为NMM,其中门脉高压症(PH)25例,非结核性腹膜炎20例,结核性腹膜炎(TBP) 15例,癌性腹膜炎(CP) 20例.观察不同性

  13. 正常胰腺不同部位的多层螺旋CT灌注成像研究%A study on multi-slice spiral CT perfusion imaging in different parts of normal pancreas

    Institute of Scientific and Technical Information of China (English)

    张喜荣; 黄小华; 董国礼; 张小明; 敬宗林; 郭静

    2012-01-01

    目的 应用多层螺旋CT灌注成像技术,探讨正常胰腺头、体和尾部的血流灌注特点.方法 选择临床行中上腹增强CT检查并符合正常胰腺纳入标准的患者35例,采用Toshiba Aquilion 16层螺旋CT先行平扫,在胰腺头、体和尾部显示完整的中心层面进行胰腺同层动态增强扫描,将扫描后所得影像数据传输到Vitrea 2.0后处理工作站,采用Toshiba体部灌注软件对正常胰腺各部位灌注参数做三点测量,其每部三点测量的平均值视为各部灌注参数最后值,并对各部灌注参数行统计学分析.结果 正常胰腺头部、体部和尾部的血流量(BF)、血容量(BV)、表面通透性(PS)和平均通过时间(MTT)的测量值分别为:头部(128.34±29.23) mL·100 g-1·min-1,(43.19±13.77) mL/100 g,(218.39±99.21) mL·100 g-1·min-1,(299.26±81.99)0.1 s;体部 (136.20±23.00) mL·100 g-1·min-1,(44.63±13.74) mL/100 g,(223.20±73.82) mL·100 g-1·min-1,(310.99±59.00) 0.1 s;尾部(128.04±27.67) mL·100 g-1·min-1,(46.04±20.14) mL/100 g,(232.24±76.65) mL·100 g-1·min-1,(299.96±71.45) 0.1 s.3组参数间均无统计学意义(P>0.05).结论 正常胰腺头部、体部和尾部供血动脉有所差异,但各部组织血流灌注基本一致.%Objective To explore the blood flow perfusion characteristics of different parts of normal pancreas by means of multi-slices spiral CT perfusion imaging. Methods Thirty-five patients without pancreatic disease,received contrast-enhanced CT exami-nation for the venter superior abdomen by 16-slice spiral CT. The completely displayed center level in the head,body and tail of nor-mal pancreas were examined by dynamic enhancement scanning. These data were processed on a Start Vitrea 2. 0 workstation by using Toshiba body software package. The three-point measurement approach was used to examin the parameters of blood flow (BF) ,blood volume (BV) ,permeability surface (PS) and mean transit time (MTT) of pancreatic tissues in

  14. 多层螺旋CT小肠造影对克罗恩病活动度的评估价值%Evaluation of Crohn's disease activity with multi-slice CT enterography

    Institute of Scientific and Technical Information of China (English)

    亓昌珍; 章士正; 刘义涛; 胡鹏

    2015-01-01

    Objective To discuss the diagnostic value of Crohn's disease activity with multi-slice CT enterography.Methods MSCTE examination data of 88 cases of CD patients by clinical,endoscopy,pathology confirmed in Sir Run Run Shaw Hospital from January 2013 to June 2014 were analysed.According to the Harvey-Bradshaw index,all of CD patients were divided into the active phase group and remission phase group.Imaging findings of two groups were compared.To explore the relationship between MSCTE findings and CRP/ESR of CD patients.Results The wall thickness (8.2 ± 2.6)mm and enhancement degree(112 ± 16)HU in active phase group were higher than the wall thickness(5.4 ± 1.6)mm and enhancement degree(93 ± 17)HU in the remission phase group(P < 0.01).The incidences of intestinal wall stratification enhancement,comb sign,swollen lymph nodes,phlegmon,intestinal fistula,intestinal stenosis in active phase group (88.5%,72.1%,77%,45.9%,26.2%,65.6%) were significantly higher than those in remission phase group (29.6%,18.5%,25.9%,0,3.7%,37%) (P <0.05).The incidences of intestinal wall homogeneous enhancement in remission phase group(70.4%) were higher than those in active phase group(11.5%) (P < 0.01).There was no significant difference in the incidences of abscesse in two groups (P > 0.05).CRP was correlated with the wall thickness and enhancement degree,abnornlal mesentery vascularity,lymph node enlargement,phlegmon,intestinal fistula (r > 0.2,P < 0.05).ESR was correlated with the wall enhancement degree,abnormal mesentery vascularity,lymph node enlargement and phlegmon (r > 0.2,P < 0.05).Conclusion CT enterography can adequately demonstrate mural abnormalities and assess the presence of extramural complications,which are helpful in evaluating the activity of Crohn's disease.%目的 探讨多层螺旋CT小肠造影(MSCTE)在克罗恩病活动度中的评估价值.方法 收集2013年1月至2014年6月在浙江大学附属邵逸夫医院经

  15. Reconstruction and measurement of optic nerve sheath imaging in normal population with multi-slice spiral CT%正常人眶内段视神经的CT重建和参数测量

    Institute of Scientific and Technical Information of China (English)

    游勇; 成洪波; 樊宁; 王宁利; 杨洁; 刘璐; 刘旭阳

    2015-01-01

    Background Optical nerve damage of glaucomatous eyes is associated with intracranial pressure.Conventional method of evaluating intracranial pressure is to measure cerebrospinal pressure by lumber puncture.However,the measurement of intraorbital optical nerve parameters,a novel method of evaluating intracranial pressure,is introduced in this field.Objective This study was to measure and analyze the intraorbital optic nerve sheath diameter (ONSD) and cross sectional area (ONSA) in normal population using multi-slice spiral CT.Methods This study protocol was approved by Clinical Ethic Committee of Shenzhen Chinese Traditional Medical Hospital and followed Hersinki Declaration.Informed consent was obtained from each individual prior to any medical examination.One hundred and five eyes of 105 normal persons with normal cerebral CT image were enrolled in Shenzhen Chinese Traditional Medical Hospital from January 2012 to September 2013.Cerebral volume was scanned in all the individuals by 64 slice spiral CT.The brain images were obtained for the curve planar rebuilding of intraorbital optical nerve on image post-processing workstation.The maximum and minimum of ONSD and the ONSA in axial sections at 3,6,9,12 and 15 mm far away from globe wall were measured using a standardized technique to analyze the change of optical nerve parameters at different point locations.These parameters were compared in different gender or eyes.The correlation among age and the optical nerve parameters at 3 mm far away from globe wall was evaluated by multivariate regression analysis.Results The average maximal ONSDs were (6.24±0.47), (5.56±0.44),(5.18±0.43),(4.82±0.41) and (4.69±0.41) mm;the average minimal ONSDs were (5.56±0.50),(4.97± 0.41) ,(4.55±0.35),(4.26±0.39) and (4.10±0.40) mm;the average ONSAs were (27.68±4.40),(22.02±3.35) , (18.74± 2.75) , (16.34±2.72) , (15.40±2.68) mm2 at 3,6,9,12 and 15 mm far away from posterior eyeball wall,respectively, showing significant

  16. Ultra-fast MRI of the human brain with simultaneous multi-slice imaging

    Science.gov (United States)

    Feinberg, David A.; Setsompop, Kawin

    2013-04-01

    The recent advancement of simultaneous multi-slice imaging using multiband excitation has dramatically reduced the scan time of the brain. The evolution of this parallel imaging technique began over a decade ago and through recent sequence improvements has reduced the acquisition time of multi-slice EPI by over ten fold. This technique has recently become extremely useful for (i) functional MRI studies improving the statistical definition of neuronal networks, and (ii) diffusion based fiber tractography to visualize structural connections in the human brain. Several applications and evaluations are underway which show promise for this family of fast imaging sequences.

  17. The value of multi-slice spiral CT perfusion imaging in evaluating the changes of blood supply of hepatocellular carcinoma before and after transcatheter hepatic arterial chemoembolization%多层螺旋CT灌注成像对肝癌经导管肝动脉栓塞化疗前后血供变化的应用价值

    Institute of Scientific and Technical Information of China (English)

    周霖; 邹文远; 陈玉峰

    2010-01-01

    目的 研究多层螺旋CT灌注成像在评价肝癌经导管肝动脉栓塞化疗(TACE)前后血流动力学改变中的价值.方法 17例肝癌患者TACE术前及术后行CT灌注扫描.计算肝血流量(HBF)、肝血容量(HBV)、平均通过时间(MTT)、毛细血管表面通透性(PS)、肝动脉灌注分数(HAF),并计算肝动脉灌注量(HAP)、门静脉灌注量(PVP).根据各灌注参数值评价肝癌TACE前后血流动力学改变.结果 TACE术后,HBF、HBV和HAP[(167.89±96.06)ml/(100 g·min),(14.95±15.13)ml/100 g,(97.71±68.18)ml/(100g·min)]较TACE术前[(250.59±129.56)ml/(100 g·min),(24.44±20.03)ml/100 g,(184.61±178.83)ml/(100 g·min)]减少(P0.05).结论 肝脏灌注参数可有效评价TACE前后肝癌组织的血流灌注改变,具有重要的临床应用价值.%Objective To study the multi-slice spiral CT (MSCT) perfusion imaging in evaluating the changes of blood supply of hepatocellular carcinoma( HCC ) before and after transcatheter hepatic arterial chemoembolization (TACE). Methods Before and after TACE, MSCT perfusion was performed in 17 patients with HCC. The perfusion indexes such as hepatic blood flow (HBF), hepatic blood volume(HBV),mean transit time (MTT),hepatic arterial fracture (HAF),permeability surface (PS), hepatic artery perfusion (HAP), portal venous perfusion (PVP) were calculated. The hemodynamic changes of HCC after TACE were evaluated according to perfusion parameters. Results After TACE, HBF,HBV and HAP found in MTT and PS before and after TACE (P > 0.05). Conclusion The parameters of MSCT perfusion imaging( HBF, HBV and HAP) can effectively evaluate the hemodynamic changes of HCC after TACE, and has important value in chnical application.

  18. 多排螺旋CT(MSCT)动态增强对孤立性肺结节血流模式的评价%Evaluation of Blood Flow Patterns of Solitary Pulmonary Nodules with Dynamic Multi-slice Spiral Computed Tomography

    Institute of Scientific and Technical Information of China (English)

    LI Shenjiang; 李慎江; XIAO Xiangsheng; 肖湘生; LI Huimin; 李惠民; LIU Shiyuan; LI Chengzhou; ZHANG Chenshi; TAO Zhiwei; YANG Chunshan

    2004-01-01

    Objective: To evaluate the efficacy of dynamic multi-slice spiral computed tomography (MSCT)for providing quantitative information about blood flow patterns of solitary pulmonary nodules (SPNs)and differentiating solitary pulmonary nodules (SPNs). Methods: 37 patients with SPNs (diameter≤4cm; 24 with maliagnant; 6 with benign; 7 with inflammatory) underwent multi-location dynamic contrast material-enhanced (90 mL, 4 mL/s) serial CT. Peak height and ratio of peak height of the SPN to that of the aorta were measured. Precontrast attenuation was recorded. Perfusion was calculated from the maximum gradient of the time-attenuation curve and the peak height of the aorta. Results: Peak heights of malignant (37.98 HU±17.97) and inflammatory (43.86 HU±14.20) SPNs were significantly higher than those of benign SPNs (5.65 HU±6.43) (P<0.001; P<0.001). No statistically significant difference in the peak height was found between malignant and inflammatory SPNs (P=0.647>0.01). SPN-to-aorta ratio in inflammatory SPNs (20.78%±4.14) was significantly higher than that in benign (2.00%±2.26) and malignant (14.63%±6.22) SPNs (P<0.001; P=0.021<0.05). SPN-to-aorta ratio in malignant SPNs was significantly higher than that in benign SPNs (P<0.001). Perfusion value in inflammatory SPNs [78.39 mL/(min.100g)±55.18] was significantly higher than that of benign [2.13 mL/(min.100g)±2.84] and malignant [33.91mL/(min.100g)±15.58] SPNs (P<0.001; P=0.001<0.01). Perfusion value in malignant SPNs was significantly higher than that in benign SPNs (P<0.001). Precontrast attenuations of inflammatory (39.36HU±9.57)and benign (37.73 HU±8.39) SPNs were lower than that of malignant SPNs (45.73 HU±4.21)(P=0.04<0.05; P=0.014<0.05). No statistically significant difference in the precontrast attenuation was found between benign and inflammatory SPNs (P=0.836>0.01). Conclusion: MSCT provides quantitative information about blood flow patterns of solitary pulmonary nodules

  19. Analysis of imaging findings of multi-slice CT enterography in patients with Crohn's disease%Crohn病的多层螺旋CT 小肠造影征象分析

    Institute of Scientific and Technical Information of China (English)

    成科; 邓生德

    2015-01-01

    目的:分析Crohn病的多层螺旋CT小肠造影(multislice computer tomography enterography ,MSCTE)影像征象,并讨论其对该病的诊断价值。方法回顾性分析28例经内镜、手术、病理证实的Crohn病的MSCTE影像学资料,全部患者行C T平扫和动脉期、静脉期增强扫描,并行M PR、厚层M IP等重建。结果28例中单纯小肠受累(9/28),小肠‐结肠同时受累(16/28),单独结肠受累(3/28),病变以累及回肠末端最为常见(20/28)。M SC T E表现:肠壁增厚(28/28),肠壁厚度4.5~23.2mm ;增强扫描肠壁分层状强化(19/28),均匀强化(9/28),肠腔狭窄(15/28),肠系膜淋巴结增大(19/28),病变肠管周围肠系膜血管增多(15/28);MSCTE表现肠壁增厚、分层状强化、肠系膜脂肪渗出性改变、血管增多(梳征)等征象可提示克罗恩病(CD)病变处于活动期。结论 MSCTE是一种诊断Crohn病较敏感的非侵入性成像方法,可同时显示肠壁及肠腔外病变,且对CD的活动性评估具有一定优势,可作为该病首选的影像诊断方法。%Objective To analyse the MSCTE imaging fingdings and to discuss the diagnostic value of Crohn's disease . Methods 28 patients with histologically proven Crohn's disease underwent MSCTE .Imaging findings were analyzed retro‐spectively .All patients underwent CT enterography examination ,The multi‐planar reformation (MPR) ,maximum inten‐sity projection (MIP) images were generated from raw data .Results Among the 28 cases ,9 cases had lesions limited to the small intestine ,the small int estine and the colon were involved simultaneously in 16 cases ,only 3 cases had lesions limited to the colon .Terminalileum is most frequently involved in CD (20/28) ,MSCTE showed there were 28 cases of bowel wall thickening ,wich wall thickness of 4 .5~23 .2 mm ,19 cases of enhanced scanning strengthen the intestinal

  20. Multi-slice computed tomography assessment of bronchial compression with absent pulmonary valve

    Energy Technology Data Exchange (ETDEWEB)

    Zhong, Yu-Min; Sun, Ai-Min; Wang, Qian; Zhu, Ming; Qiu, Hai-Sheng [Shanghai Children' s Medical Center and Shanghai Jiao Tong University Medical School, Department of Radiology, Shanghai (China); Jaffe, Richard B. [Primary Children' s Medical Center, Department of Medical Imaging, Salt Lake City, UT (United States); Liu, Jin-Fen [Shanghai Children' s Medical Center, Department of Cardiothoracic Surgery, Shanghai (China); Gao, Wei [Shanghai Children' s Medical Center and Shanghai Jiao Tong University Medical School, Department of Cardiology, Shanghai (China); Berdon, Walter E. [Children' s Hospital of New York, Department of Radiology, New York, NY (United States)

    2014-07-15

    Absent pulmonary valve is a rare cardiovascular anomaly that can result in profound tracheobronchial compression. To demonstrate the advantage of multi-slice CT in diagnosing tracheobronchial compression, its severity as related to the adjacent dilated pulmonary arteries, and associated lung and cardiac lesions. We included children with absent pulmonary valve who were reviewed by multi-slice CT during a 17-year period. The number and locations of stenoses and lung lesions were noted and the severity of stenosis was categorized. The diameter of the pulmonary artery was measured and associated cardiac defects were demonstrated. Thirty-one children (14 girls and 17 boys) were included. Of these, 29 had ventricular septal defect and 2 had an intact ventricular septum. Twenty-nine children (94%) had tracheobronchial compression, judged to be mild in nine children (31%), moderate in 10 (34%) and severe in 10 (34%). The different locations of the stenosis (carina, main bronchi, lobar and segmental bronchi) were observed. And the number and location of lung lesions demonstrated that the right middle and left upper and lower lobes were often affected. The diameter of the pulmonary artery in these children was well above normal published values, and Spearman rank correlation analysis showed a correlation between the size of the pulmonary artery and the severity of the tracheobronchial stenosis. Nineteen children (61%) underwent surgery and 4 of these children had a multi-slice CT post-operative follow-up study. Absent pulmonary valve can cause significant morbidity and mortality in children. Multi-slice CT can accurately depict areas of tracheobronchial compression, associated lung lesions and cardiac defects, helping to direct the surgeon. (orig.)

  1. Clinical Value of Multi-slice Spiral CT in the Staging of Sacroiliac Arthropathy in Ankylosing Spondylitis%多层螺旋CT在强直性脊柱炎骶髂关节病变分期中的应用价值

    Institute of Scientific and Technical Information of China (English)

    王辉; 徐春生; 汪四海; 张金山; 杨佳; 刘健

    2011-01-01

    目的 探讨多层螺旋CT(multi-slice spiral CT,MSCT)在强直性脊柱炎(ankylosing spondylitis,AS)骶髂关节病变的诊断及分期中的应用价值.方法 回顾性分析82例AS患者骶髂关节的MSCT表现,对其进行分期.结果 82例中,双侧骶髂关节正常9例,单侧受累6例,双侧均受累67例;164个骶髂关节中,0级24个(构成比0.146),Ⅰ级42个(构成比0.256),Ⅱ级36个(构成比0.220),Ⅲ级54个(构成比0.329),Ⅳ级8个(构成比0.049).结论 MSCT分期为AS骶髂关节病变提供了半定量分析方法,更客观、准确地反映了患者的病情及骶髂关节受累程度,为长期随访患者的病情和疗效判断提供了客观依据.%Objective To evaluate the clinical values of multi-slice spiral CT (MSCT) in the diagnosis and staging of sacroiliac arthropathy in patients with ankylosing spondylitis(AS). Methods The MSCT features of sacroiliac arthropathy in 82 patients with AS were analyzed retrospectively, and the staging of sacroiliac arthropathy were determined by MSCT. Results Of 82 patients, there were normal bilateral sacroiliac joints in 9, unilateral involvement in 6, and bilateral involvement in 67. Of 164 sacroiliac joints, 24 (accounting for 0. 146) were classified into grade 0, 42 (accounting for 0. 256) into grade Ⅰ, 36 (accounting for 0. 220) into grade Ⅱ, 54 (accounting for 0. 329) into grade Ⅲ , and 8 (accounting for 0. 049) into grade Ⅳ. The CT features included cartilage calcification, joint space narrowing or widening, articular surface and undersurface erosion, and ligament calcification. Conclusion MSCT staging of sacroiliac arthropathy provides a method of semi-quantitative analysis on AS. It can reflect the clinical state of AS more objectively and accurately, and can provide an objective basis for judgement on the disease conditions and curative effects in patients with long-term follow-up.

  2. The clinical value of transthoracic echocardiography and Multi-slice spiral CT for evaluation of fistula diameter in patients with coronary artery fistula%经胸超声心动图及多层螺旋CT对诊断冠状动脉瘘患者的临床价值

    Institute of Scientific and Technical Information of China (English)

    李晓明; 牛宝荣; 吴山; 杨娅; 张纯

    2015-01-01

    目的:以血管造影为“金标准”,评价经胸超声心动图( transthoracic echocardiography,TTE)和多层螺旋CT( multi-slice spiral CT,MSCT)筛查冠状动脉瘘及估算瘘口直径的能力,并分析其各自的影响因素。方法回顾性分析北京安贞医院接受封堵术治疗并经血管造影确诊为冠状动脉瘘的患者,所有患者均于术前1个月内接受TTE及MSCT辅助检查。结果以血管造影结果为金标准,MSCT及TTE对冠状动脉瘘患者的明确诊断准确度为96.7%及90.0%。针对瘘口直径的测定,血管造影对瘘口直径的平均测定值为(8.70±3.50)mm,MSCT及TTE的平均估算值分别为(8.86±3.71)mm及(7.50±5.90)mm,经配对t检验,P值均>0.05。但MSCT估测值较TTE的估算值与血管造影结果的相关性更好( r值分别为0.913及0.778,P值均10.5mm时,TTE高估瘘口直径;MSCT估测结果则与血管造影间的吻合性良好。结论 TTE和MSCT对冠状动脉瘘患者的筛查准确度均较高。但是,对于瘘口直径的判断,MSCT的稳定性较TTE更佳,其术前应用可以进一步提高诊断的准确性。%Objective Angiography as a reference to evaluate the clinical value of transthoracic echocardiography ( TTE) and multi – slice apiral CT ( MSCT) for evaluation of fistula diameters in patients with coronary artery fis-tula( CAF) ,and to investigate their influencing factors. Method Thirty consecutive patients who had coronary artery fistula were revealed by angiography through the interventional operation in Anzhen Hospital. Result Accuracy of MSCT and TTE for diagnosis of CAF are 96. 7% and 90. 0% ,with angiography as reference. For CAF patients, di-ameter of fistula determined by MSCT ,TTE and Angiography were (8. 86 ± 3. 71) mm,(7. 50 ± 5. 90) mm and (8. 70 ± 3. 50)mm (all P>0. 05). But, fistula diameter revealed by MSCT was better related with angiography re-sult than that revealed by TTE (r=0. 913 and 0. 778,P<0. 001). And through Bland-Altman analyze

  3. 多层螺旋 CT 多平面重组在诊断先天感音神经性耳聋儿童内耳畸形中的应用%The diagnostic value of multiplanar reconstruction of multi-slice spiral CT in pediatric sensorineural hearing loss children induced by inner ear malformation

    Institute of Scientific and Technical Information of China (English)

    胡辉军; 李国照; 王东烨; 张翔; 沈君

    2015-01-01

    Objective To investigate the diagnostic value of multiplanar reconstruction (MPR) of multi-slice spiral CT (MSCT) in inner ear malformation of children. Methods Retrospective analysis of 223 children in Sun Yat-Sen Memorial Hospital suspected sensorineural hearing loss (SNHL) clinically was performed between September 2010 and March 2014. All the patients received MSCT scan and 68 patients of inner ear malformation were detected. Deformed bony labyrinths of 68 patients and two cases of normal inner ear were reconstructed with the method of MPR on basis of raw data of MSCT images by one radiologist. In 68 patients of inner ear malformation, there were 33 males and 35 females (aged from 9 days to 16 years). Two senior radiologists evaluated the MSCT manifestations of 68 patients and than statistics analysis of classification for inner ear malformation were performed. Results Sixty-eight patients (5 patients with single ear malformation, 63 patients with bilateral ear malformation, 131 ears in total) with SNHL were clearly shown by MPR images. There were 33 ears of cochlear malformation, 39 ears of vestibular malformation, 42 ears of semicircular canal malformation, 18 ears of internal auditory canal malformation and 86 ears of vestibular aqueduct malformation. In 68 patients (131 ears), single constructive malformation was detected in 8 ears (6. 1% ), two or more kinds of combined malformations were detected in 123 ears (93. 9% ). Conclusions Most of these patients suffered from two or more kinds of combined malformations. MPR images can display the structures of cochlear, vestibule, semicircular canal, internal auditory canal and vestibular aqueduct. The application of this kind of post-processing technology is expected to improve the detection rate of inner ear malformation, especially the various structural malformations, which is conducive to the treatment decisions making and surgical planning.%目的:探讨多层螺旋 CT(MSCT)多平面重组(MPR)技术在

  4. 多层螺旋CT灌注成像对原发性肝癌的评价%Evaluation of multi-slice CT perfusion imaging in hepatocellular carcinoma

    Institute of Scientific and Technical Information of China (English)

    燕平

    2011-01-01

    目的 探讨多层螺旋CT灌注成像在原发性肝癌中的价值.方法 对25例原发性肝癌进行多层螺旋CT灌注成像,动态电影模式扫描,所有数据经工作站软件处理并计算组织血流量(blood flow,BF)、血容量(blood volume,BV)、平均通过时间(mean transittime,MTT)、毛细血管通透性(permeability surface,PS)、肝动脉供血分数(hepatic arterial fraction,HAF),比较肿瘤组织、瘤旁组织及正常肝组灌注参数的变化.结果 肝癌组织BF、HAF 明显高于瘤旁组炽及正常肝组织,而MTT明显降低,且具有显著性差异;BV和PS值与正常组织无显著差异.结论 肝癌CT灌注参数(BF、HAF和MTT)可有效的评价原发性肝癌的血流动力学改变,具有重要临床价值.%Objective To evaluate the application value of multislice CT perfusion imaging in hepatocellular carcinoma (HCC). Methods Perfusion scans were performed with 16-slice CT in 25 patients with HCC. Contrast medium -enhanced dynamic CT was performed with a statictable position for 50 seconds, and the data were analyzed with software to calculate tissue blood flow (BF), blood volume(BV), mean transittime(MTT), permeability surface(PS), and hepatic arterial fraction(HAF). Peefusion parameters of tumor, the periphery of tumor and normal liver were compared. Results HCC showed high BF, HAF, HAP and short MTT compared with those of the periphery of HCC and normal liver.Conclusion The changes of hepatic perfusion parameters (BF, HAF and MTT) have great valueon evaluating the hemodynamics of HCC.

  5. Multi-slice Spiral CT in Cochlear Implantation on Clinical Significance of Display Cochlear Inner Electrode%多排螺旋CT在人工耳蜗植入术后对蜗内电极显示的临床意义

    Institute of Scientific and Technical Information of China (English)

    周万勇; 马玉; 巩武贤

    2013-01-01

    目的 探讨多排螺旋CT (MSCT)在人工耳蜗植入术后对蜗内电极显示的应用价值及临床意义.方法 对28例已行人工耳蜗植入术的患者做MSCT横断扫描,MPR重组及容积再现技术(VRT)重建,扫描参数为120kv,80mas,0.6mm准直器宽度,重建图像厚度0.6mm,间隔0.1mm,骨算法重建,对特殊患者行VRT三维重建.结果 25例显示植入电极在耳蜗内呈点状高密度影,VRT图像显示电极在耳蜗内呈自然螺旋状,无扭曲、滑脱与耳蜗走形一致,其中23例患者,耳蜗内显示植入电极12对,2例显示11对.2例植入失败,其中1例并发中耳炎,电极脱落仅于耳蜗底转,1例电极位于耳蜗外.内耳畸形成功植入1例,VRT图像显示植入耳蜗前段4-5电极.结论 MSCT扫描结合MPR及VRT重建对人工耳蜗植入术后植入电极在耳蜗内形态、位置、数目有准确、清晰、直观显示,对术后患者的康复评估有重要帮助.%Objective To investigate the multi-slice spiral CT in the cochlear implantation on application value display cochlear inner electrode and its clinical significance.Methods Patients with have cochlear implantation was performed in 28 cases of MSCT transverse scanning,MPR recombination and volume rendering technique (VRT) reconstruction,scanning parameters for 120kv,80mas,0.6mm collimation,reconstruction thickness 0.6mm,interval 0.1 mm,bone algorithm reconstruction,for special patients underwent VRT three-dimensional reconstruction.Results Of the 25 cases showed punctate hyperdense electrodes implanted in the cochlea,VRT image display electrode is natural spiral in the cochlea,no distortion,spondylolisthesis and cochlear out of shape,in which 23 cases,cochlear implanted electrodes to display 12,2 cases showed that 11 of the.2 cases of implant failure,of which 1 cases complicated by otitis media,electrode off only in the basal turn of the cochlea,1 cases located in the outer electrode.In 1 cases with inner ear malformation successful

  6. Experimental research of acetabular abduction angle and anteversion measurement by three-dimensional reconstruction of multi-slice spiral CT%多层螺旋CT三维重建测量髋臼外展角及前倾角的实验研究

    Institute of Scientific and Technical Information of China (English)

    范新成; 葛东; 刘峰; 魏开斌; 马振波; 张伟; 赵伟; 李军; 朱海涛; 初培罡

    2014-01-01

    Objective To investigate a new method of three-dimensional reconstruction of multi-slice spiral CT in measurement of acetabular abduction angle and acetabular anteversion. Methods The research objects were 60 acetabulars of 30 pelvic specimens, acetabular abduction angle and acetabular anteversion were measured respectively by radiological and actual measurements. The first one using digital X-ray photography and three-dimensional reconstruction of multi-slice spiral CT. The second one using a protractor and digital goniometer two methods. Results The acetabular abduction angle and anteversion were (48.61±2.31)° and (15.82±4.62)° respectively, there was no statistically significant difference of these two angles between actual measurement and radiological measurement(P>0.05). There were no significant differences for each angle between radiological and actual measurements(P>0.05). Conclusions The measurement of acetabular abduction angle and anteversion by MSCT three-dimensional reconstruction were accurate, which provide a new and standardized method of measurement of acetabular abduction angle and anteversion. The digital goniometer provide an accurate and convenient new method for specimens’ anatomical measurements.%目的:探讨应用多层螺旋CT(multi-slice spiral CT,MSCT)三维重建精确测量髋臼外展角及前倾角的新方法。方法选用30具成人完整骨盆标本共60个髋臼为研究对象,应用放射学方法及实际测量法分别对其外展角、前倾角进行测量,放射学方法采用数字化 X 线摄影(digital X-ray radiography,DR)及MSCT三维重建两种方法,实际测量采用量角器及数显角度仪两种方法。结果 MSCT重建法测得的髋臼外展角为48.61°±2.31°,前倾角为15.82°±4.62°,与实际测量结果比较,差异均无统计学意义(P>0.05);放射学方法与实际测得的髋臼外展角、前倾角分别比较,差异均无统计学意义(P>0.05

  7. 多层螺旋CT血管成像在脑动静脉畸形诊断及治疗中的价值%Value of multi-slice spiral CT angiography in diagnosis and treatment of cerebral arteriovenous malformations

    Institute of Scientific and Technical Information of China (English)

    余海浪; 庹秀均; 李战辉; 张应和

    2013-01-01

    目的 探讨脑动静脉畸形(CAVM)在多层螺旋CT血管造影(MSCTA)中的表现及MSCTA的临床价值.方法 收集36例行MSCTA检查的CAVM患者的资料,采用容积再现重组(VR)血管生长技术(AV)进行血管重建,分析供血动脉、引流静脉的表现.结果 36例CAVM患者中,病变累及枕叶10例,颞叶9例,额叶2例,顶叶3例,枕叶、小脑半球7例,颞、枕叶3例,额、顶叶2例,均清楚显示畸形血管团、供血动脉及引流静脉;4例合并血管畸形内动脉瘤,2例合并血管畸形外动脉瘤,3例蛛网膜下腔出血,6例脑出血.结论 MSCTA能清楚显示CAVM的畸形血管团、供血动脉、引流静脉及合并的动脉瘤.%Objective To evaluate the manifestation of cerebral arteriovenous malformations (CAVM) on multi-slice spiral CT (MSCT) angiography and the clinical value of this examinaion.Methods The data on 36 patients with CAVM undergoing MSCT angiography were collected.Vascular reconstruction were performed by volume rendering and AV.The manifestations of feeding arteries and draining veins were then analyzed.Results Among these 36 patients with cerebral arteriovenous malformations,ten patients had the lesion in occipital lobe,nine in temporal lobe,two in frontal lobe,three in parietal lobe,seven in occipital lobe and cerebellar hemisphere,three in occipital and temporal lobe,and two in frontal and parietal lobe,with a clear display of masses of deformed vessels,feeding arteries and draining veins; 4 patients were complicated by intra-aneurysm of CAVM,2 were complicated by extra-aneurysm of CAVM,3 concurred with subarachnoid hemorrhage,and 6 concurred with cerebral hemorrhage.Conclusions Multi-slice spiral angiography can clearly detect masses of deformed vessels,feeding arteries,draining veins,and coexisting aneurysms.

  8. On-site Rapid Diagnosis of Intracranial Hematoma using Portable Multi-slice Microwave Imaging System

    Science.gov (United States)

    Mobashsher, Ahmed Toaha; Abbosh, A. M.

    2016-11-01

    Rapid, on-the-spot diagnostic and monitoring systems are vital for the survival of patients with intracranial hematoma, as their conditions drastically deteriorate with time. To address the limited accessibility, high costs and static structure of currently used MRI and CT scanners, a portable non-invasive multi-slice microwave imaging system is presented for accurate 3D localization of hematoma inside human head. This diagnostic system provides fast data acquisition and imaging compared to the existing systems by means of a compact array of low-profile, unidirectional antennas with wideband operation. The 3D printed low-cost and portable system can be installed in an ambulance for rapid on-site diagnosis by paramedics. In this paper, the multi-slice head imaging system’s operating principle is numerically analysed and experimentally validated on realistic head phantoms. Quantitative analyses demonstrate that the multi-slice head imaging system is able to generate better quality reconstructed images providing 70% higher average signal to clutter ratio, 25% enhanced maximum signal to clutter ratio and with around 60% hematoma target localization compared to the previous head imaging systems. Nevertheless, numerical and experimental results demonstrate that previous reported 2D imaging systems are vulnerable to localization error, which is overcome in the presented multi-slice 3D imaging system. The non-ionizing system, which uses safe levels of very low microwave power, is also tested on human subjects. Results of realistic phantom and subjects demonstrate the feasibility of the system in future preclinical trials.

  9. Diagnostic Value of Multi-slice Spiral CT Multi-phase Scanning in Early Sage Renal Pelvis Cancer%多层螺旋CT多期扫描对早期肾盂癌的诊断价值

    Institute of Scientific and Technical Information of China (English)

    葛芳清; 韩希年

    2013-01-01

    目的 探讨多层螺旋CT多期扫描对早期肾盂癌的诊断价值.方法 回顾性分析5 8例肾盂癌的CT表现并进行CT分期,与组织病理学结果对照.结果 CT图像分期A期(早期)1 8例、B期3 2例、C期8例;病理分期早期(A期)24例、B期26例、C期8例.24例A期肾盂癌中,CT分期正确的1 7例,7例A期误判为B期,1例B期误判为A期.CT评判早期肾盂癌的敏感性70.8%(17/24),特异性97%(32/33),阳性预测值94.4% (17/18)%.结论 多层螺旋CT多期扫描对早期肾盂癌的判断有很高的特异性,对临床手术方案的选择起到很好的指导作用.%Objective To investigate the diagnostic value of enhanced multi-phase spiral CT in the early renal pelvis cancer.Methods CT manifestations of 58 cases with renal pelvis cancer were retrospectively analyzed and CT staged,and compared to its pathological results.Results CT image stage showed A stage (early stage) in 18 cases,B stage in 32 cases,C stage in 8 cases; pathological stage showed A stage (early stage) in 24 cases,B stage in 26 cases,C stage in 8 cases.Of all 24 cases with A stage renal pelvis cancer,17 cases were diagnosed correctly,and 7 cases with A stage cancer were misdiagnosed as B stage,and 1 case with B stage cancer misdiagnosed as A stage.The sensitivity,specificity,positive predictive value of CT stage in evaluation of early renal pelvis cancer were 70.8%(17/24),97% (32/33),and 94.4% (17/18) %.Conclusion Enhanced multi-phase spiral CT has high specificity in diagnosis of early stage renal pelvis cancer.It plays an important role in clinical operation scheme selection.

  10. 腰椎多层螺旋CT低剂量扫描参数优化的研究%Study of Multi-slice Spiral CT Low-dose Scanning Parameters Optimization in the Lumbar Spine

    Institute of Scientific and Technical Information of China (English)

    董艳军; 张磊磊; 唐晓; 白男男; 胡蓬勃; 郭兰田

    2014-01-01

    目的:评价不同扫描条件腰椎多层螺旋CT扫描对成像质量及辐射剂量的影响,探讨多层螺旋CT在腰椎软组织病变扫描中适宜的低剂量扫描参数。方法通过CT设备扫描患者腰椎,以240 mAs为起点,逐渐降低管电流量,记录CT主机上显示的辐射剂量;评价图像质量采用adw 4.3工作站,统计学处理采用SPSS18.0软件。结果管电流量80 mAs扫描所获得的图像评分均不低于3分,其产生的辐射剂量为6.81 mGy;而管电流量240 mAs扫描所获得的图像评分均为4分,其产生的辐射剂量为20.22 mGy。结论腰椎软组织多层螺旋CT低剂量扫描的适宜扫描参数为80 mAs。%Objective To evaluate the effect of lumbar spine multiple-slice spiral CT different scanning schemes on image quality and radiation dose and investigate the suitable low-dose scanning parameters of multiple-slice spiral CT in lumbar spine soft tis-sue lesions. Methods We scanned the patients' lumbar spine by CT equipment. We started with 240mAs and gradually reduced mAs. We also recorded the radiation dose showed by the CT host computer and evaluated image quality by the adw 4.3 worksta-tion. We analyzed data through SPSS 18.0. Results All image quality scores were no less than 3 points at 80mAs, and the radia-tion dose at 80mAs was 6.81mGy. All image quality scores were 4 points at 240mAs, and the radiation dose at 240mAs was 20.22mGy. Conclusion The suitable multiple-slice spiral CT low-dose scanning parameters in the lumbar spine soft tissue lesions is 80mAs.

  11. The value of multi-slice CT and MRI for early complications of inguinal hernia repair%MSCT 和 MRI 对腹股沟疝修补术后早期并发症的诊断价值

    Institute of Scientific and Technical Information of China (English)

    张勇; 周玉梅; 陈淑君; 李洪; 王周旋; 惠庆涛; 邓鸿义; 倪帮高; 明兵

    2015-01-01

    Objective To evaluate the value of MSCT and MRI in diagnosis of early postoperative complications of inguinal hernia repair (IHR).Methods Imaging and clinical data in 1 6 patients with early complications of IHR were analyzed retrospectively.Re-sults Among the complications,postoperative infection in 2 was found including incision infection in 1 and groin cellulitis in other 1. CT showed swelling abdominal wall and heterogeneous enhancement for incision infection,and inguinal mass,deep inguinal ring thickening,edema of residual sac with fluid and air collections for groin cellulitis.Seroma was found in 8,and CT and MRI demon-strated residual sac effusion,spermatic cord thickening and spermatic vascular tortuosity.Residual sac edema was found in 4,and CT and MRI showed thickening spermatic cord without effusion in residual sac or scrotum.Effusions between patch and anterior abdom-inal wall were detected by MRI in 2,one of which was accompanied by patch shrinking.Conclusion With specific clinical background for early complications of IHR,MSCT and MRI provide more anatomical information of inguinal region,which may contribute to di-agnosis and treatment of early postoperative complications.%目的:探讨 MSCT 和 MRI 对腹股沟疝修补术后早期并发症的诊断价值。方法回顾性分析16例腹股沟疝修补术后出现早期并发症患者的临床和影像资料。结果16例中包括术后感染2例,其中1例为切口感染,CT 表现为腹壁软组织肿胀,增强不均匀强化,1例为腹股沟蜂窝组织炎,CT 表现为腹股沟肿块,腹股沟管内环增厚,残留疝囊水肿伴疝囊积液、积气;血清肿8例, CT 和 MRI 表现为残留疝囊积液,精索增粗,精索血管迂曲;残留疝囊水肿4例,CT 和 MRI 显示精索增粗,残留疝囊或阴囊内未见积液;补片周围积液2例,MRI 显示补片与前腹壁之间少量积液,其中1例伴有补片皱缩。结论腹股沟疝修补术后早期并发症

  12. Gastrointestinal stromal tumor of the multi-slice spiral CT in diagnosis and differential diagnosis%胃肠道间质瘤的多层螺旋CT诊断价值

    Institute of Scientific and Technical Information of China (English)

    沈昌山; 胡元成; 郑桥如

    2012-01-01

    目的 探讨多层螺旋CT(MSCT)对胃肠道间质瘤(GIST)的诊断及鉴别诊断价值.方法 回顾性分析15 例GIST 的临床及多层螺旋CT 资料,对肿瘤大小、密度、强化程度进行比较.结果 病灶分布于食管1 例,胃7 例,十二指肠1 例,空肠2 例,回肠3 例,肠系膜根部1 例.MSCT 主要表现为圆形、类圆形及不规则肿块,具有跨腔内外生长或腔外生长为主的特征.良性4 例,肿瘤平扫密度均匀,增强肿瘤明显均匀强化.交界性3 例,恶性8 例,其中有7 例直径大于8 cm,肿块不规则,密度不均匀,增强肿块不均匀强化,内部出血、坏死、囊变,局部无淋巴结转移.结论 GIST 的CT 表现有一定的特征,MSCT 检查对GIST 的诊断与鉴别诊断具有重要的作用.%Objective To explore the diagnosis and differential diagnosis value of multislioe helical CT ( MSCT ) on gastrointestinal stroraal tumor (GIST). Methods The clinical and multislice spiral CT data of 15 cases GIST were retrospectively analyzed. The tumor size. density, and the degree of strength were compared. Results Distribution of lesions was found in 1 case of esophagus,7 cases of stomach, f case of duodenum, 2 cases of jejunum, 3 cases of ileura, and 1 case of the root of the mesentery. MSCT mainly showed round, quasi-round and irregular mass, with mainly features as cross inside or outside the cavity growth or outer cavity growth. There were 4 cases of benign tumor with plain uniform density and homogeneous enhancing in enhanced tumor, 3 borderline cases, and 8 malignant cases. 7 cases of which had the diameter of more than 8cm, with an irregular mass, uneven density, enhancing mass with heterogeneous enhancement, internal bleeding, necrosis, cystic change, and no local lymph node metastasis. Conclusion CT of GIST has certain characteristics. MSCT examination plays ~an important role in the diagnosis and differential diagnosis of GIST, and helps guide the treatment scheme.

  13. 16层螺旋CT多期增强扫描对小肝癌的诊断研究%Contrast-enhanced 16 multi-slice spiral CT scans for the diagnosis of small hepatocellular carcinoma

    Institute of Scientific and Technical Information of China (English)

    郭敬深; 夏广明; 罗剑云; 陈锦灿

    2011-01-01

    目的 研究小肝癌(SHCC)在16层螺旋CT( SCT)多期(动脉期、门脉期和延迟期)增强扫描的表现特征,提高小肝癌的诊断水平及评价其应用价值。方法 收集53例SHCC进行回顾性分析,所有病例均行16层螺旋CT多期增强扫描,扫描时间分别为动脉期34~40s、门脉期65~80s、延迟期4~6 min,用高压注射器经静脉注射,速率为2.5~3 ml/s,剂量为85~95 ml,观察SHCC在各期的强化方式。结果 共发现70个病灶,平扫、动脉期、门脉期和延迟期的检出率分别为70.0%、97.1%、82.9%和87.1%,动脉期的敏感性高于门脉期和延迟期。结论 16层螺旋CT多期增强扫描能充分反映SHCC在增强中的血供变化特点,提高了SHCC的检出率及定性诊断的准确性。%Objective To improve the diagnostic level for small hepatocellular carcinoma ( SHCC )by exploring the characteristic appearance of SHCC on constract-enhanced 16-slice spiral CT multi-phase ( arterial, portal venous phase, and delayed phase ) scans. Methods The data on 53 patients with SHCC were retrospectively analyzed. All the patients received 16-slice spiral CT multi-phase scans, with scanning time of 34-40s at arterial phase, 65-80s at portal venous phase, and 4-6min at delayed phase. The constract of 85-95ml was intravenously injected at a velocity of 2.5-3 ml/s with a high pressure syringe. The enhancement patterns of SHCC were observed at different phases. Results 75lesions were found. The detection rate was 70.0% for plain scan, 97.1% for arterial phase, 82.9% for portal phase, and 87.1% for delayed phase, with a sensitivity higher in arterial phase than in portal phase and delayed phase. Conclusions Contrast-enhanced 16-slice spiral CT scans can fully reflect the enhancing characteristics of blood supply in SHCC, improving the detection rate and the accuracy of diagnosis.

  14. Study on Relationship between Gastric Multi-slice Spiral CT Perfusion Imaging and Perfusion and Tumor Factor%胃癌多层螺旋CT灌注成像及灌注参数与肿瘤因子的相关性研究

    Institute of Scientific and Technical Information of China (English)

    张颖颖; 范小波; 亓子坤

    2015-01-01

    Objective To explore the correlation between gastric cancer multi-slice spiral CT perfusion imaging and perfusion and tumor factor. Methods 32 cases of gastric cancer patients random selected from Department of oncology in our hospital from 2010 January to 2012 September as the observation group, 40 cases healthy subjects randomly chosen in the physical examination center as control group, the two groups of subjects were using CT perfusion imaging, compared blood flow perfusion software into the packet processing after the CT perfusion (Perfusion)(blood volume or per unit time per 100gin renal tissue)、blood volume (100g in renal tissue of blood within the capacity of (BV))、peak enhancement (PEI), time to peak (TTP),mean transit time (MTT), permeability surface (PS) differences and related tumor factor levels of two groups, and analyzed the correlation between CT perfusion parameters and tumor factor by using Pearson analysis method. Results The observation group and the control group Perfusion, PEI, TTP, PS with significant difference (p0.05); observation group tumor factor CEA, AFP, CA199, CA72-4 levels were significantly higher than those in the control group and the difference was statistically significant (p0.05);观察组的肿瘤因子CEA、AFP、CA199、CA72-4水平均显著的高于对照组且差异具有统计学意义(p<0.05);Perfusion、PEI、PS与肿瘤因子CEA、AFP、CA199、CA72-4呈显著的正相关性, TTP与肿瘤因子CEA、AFP、CA199、CA72-4呈显著的负相关性。结论通过对胃癌患者胃癌进行多层螺旋CT灌注成像检测,可以有效分析肿瘤因子的水平,两者间存在良好的相关性。

  15. Diagnostic Value of Low Dose Multi-slice Spiral VHRCT (MSCT) CT in Children with Chronic Interstitial Lung Disease%小剂量多层螺旋CT(MSCT)VHRCT在小儿慢性肺间质病变中的诊断价值

    Institute of Scientific and Technical Information of China (English)

    李燕北; 李云秀; 王宝军

    2016-01-01

    目的:分析研讨小剂量多层螺旋CT(MSCT)VHRCT在小儿慢性肺间质病变中的诊断价值。方法:此研究中所研讨的32例患儿均随机从2013年5月至2014年11月期间我院收治的小儿慢性肺间质病变患儿中选取而出,回顾分析患儿临床病历资料,32例患儿均接受小剂量多层螺旋CT(MSCT)容积数据重组高分辨和HRCT扫描,对比此两者检查扫描方式在囊状透亮部位、网格影、结节影、肺大泡影、磨玻璃密度影等差异性,对比诊断准确性和图像质量评分状况。结果:对比同层面囊状透亮部位、网格影、结节影、肺大泡影、磨玻璃密度影、蜂窝影等显影状况,HRCT方式比MSCT方式要稍微高一点,但组间数据无统计学意义(P>0.05)。小剂量MSCT检查方式在图像质量评分上比VHRCT检查方式要稍高,但组间数据无统计学意义(P>0.05);在诊断准确率上,小剂量MSCT(93.75%)和VHRCT方式(96.87%)比较,虽后者稍高,但组间数据无统计学意义(P>0.05)。结论:HRCT检测结果比小剂量多层螺旋CTMSCT检查结果更加具有优势性,特别是针对小剂量多层螺旋CTMSCT和大龄患儿检查判定不佳时,可依据实际状况考虑是否采用HRCT,因此,建议临床在诊断疾病时,按照患儿实际状况确定检查方式,确保诊断准确性。%ABSTRACT:Objective:To analyze and discuss the value of low dose multi-slice spiral VHRCT (MSCT) CT in the diagnosis of chronic interstitial lung disease in children.Methods:32 children with this research studied were randomly from 2013 May to 2014 November period in our hospital pediatric chronic lung interstitial lesion in children with selected out, children with clin-ical data were retrospectively analyzed, 32 cases underwent low dose multislice spiral CT (MSCT) volume number according to the restructuring of high resolution scanning and HRCT, compared with the two scanning way

  16. Diagnostic value of combination of 99mTc-MIBI imaging,multi-slice spiral CT and tumor marker measurements for lung cancer%99mTc-MIBI肺显像、多排螺旋CT和肿瘤标志物检测对肺癌的诊断价值

    Institute of Scientific and Technical Information of China (English)

    党国际

    2009-01-01

    目的 探讨99Tc-甲氧基异丁基乙腈(99Tc-MIBI)亲肿瘤显像、多排螺旋CT、血清肿瘤标志物[癌胚抗原(CEA)、细胞角蛋白19片断(CYFRA21-1)、神经元特异性烯醇化酶(NSE)]检测联合应用对肺癌的诊断价值.方法 对350例临床怀疑为肺癌患者的99mTc-MIBI亲肿瘤显像、多排螺旋CT、血清肿瘤标志物榆测资料进行回顾性分析,总结每种方法及三种方法联合应用诊断肺癌的灵敏度、特异度及正确度.350例患者分别经纤维支气管镜检查、手术治疗及穿刺活组织枪查、病理最后证实200例为肺癌患者.结果 三种检查方法诊断肺癌的灵敏度、特异度及正确度分别为74.5%(149/200)、68.7%(103/150)、72.0%(252/350),97.5%(195/200)、42.7%(64/150)、74.0%(259/350)及62.5%(125/200)、28.7%(43/150)、48.0%(168/350).三法联合应用为99.5%(199/200)、82.0%(123/150)、92.0%(322/350).结论 上述三种检查方法对肺癌诊断各有其独特的重要的临床价值,三种方法联合应用诊断价值更大.%Objective To explore the clinical value of the combination of three methods including 99mTc-MIBI imaging, multi-slice spiral CT and tumor markers [carcinoembryonic antigen(CEA),cytokeretin19 fragment(CYFRA21-1), neuron-specific enolase(NSE)] measurement for diagnosis of lung cancer. Methods 350 patients were performed 99mTc-MIBl imaging, multi-slice spiral CT and measurements of tumor markers apart within one week. 200 patients were proved by pathology lung cancer in all 350 patients. Results The sensitivity, specificity and accuracy obtained with the three methods and combination of three methods were 74.5 %(149/200), 68.7 %(103/150), 72.0 %(252/350);97.5 %(195/200), 42.7 %(64/150), 74.0 %(259/350);62.5 %(125/200), 28.7 %(43/150), 48.0 %(168/350) and 99.5 %(199/200), 82.0 %(123/150), 92.0 %(322/350),respectively. Conclusion The results imply that three methods has its distinct important clinical value in diagnosis of lung cancer respectively

  17. 多层螺旋 CT 口服小肠造影与胶囊内镜对不明原因腹痛患者诊断价值的对比研究%Comparison of diagnostic value of multi-slice computer tomography enterography versus capsule endoscopy for unexplained abdominal pain

    Institute of Scientific and Technical Information of China (English)

    梁晓燕; 伦伟健; 黄鹤; 贾柳萍

    2016-01-01

    Objective To compare and evaluate the diagnositic value of multi-slice computer tomography enterography (MSCTE)versus capsule endoscopy for patients with unexplained abdominal pain.Methods twenty-nine cases of unknown abdominal pain were collected.8 cases of 29 cases received MSCTE examination,24 cases received the capsule endoscopy and 3 cases received both of the examinations.Results The detection rate for lesions was 62.5% by MSCTE and 75.0% by capsule endoscopy.There was no statistical difference between the two methods(P >0.05).The detection rate in cases undergoing both examinations was 1 00%. Conclusions MSCTE and capsule endoscopy have high diagnostic value in patients with unexplained abdominal pain.The detection rate can be increased if the two methods are combined to conduct examination.%目的:对比多层螺旋 CT 口服小肠造影(MSCTE)与胶囊内镜对不明原因腹痛患者的诊断价值。方法收集29例不明原因腹痛患者,其中 MSCTE 检查8例,胶囊内镜检查24例,同时接受两种方法检查3例。结果 MSCTE 病变检出率为62.5%,胶囊内镜为75.0%,两者差别无统计学意义(P >0.05),联合两者病变检出率为100%。结论 MSCTE 与胶囊内镜检查对不明原因腹痛患者具有较高的诊断价值,二者联合诊断意义更高。

  18. Multi-slice CT angiography in the diagnosis of Takayasu's arteritis%多层螺旋CT血管成像在大动脉炎中的应用

    Institute of Scientific and Technical Information of China (English)

    马祥兴; 张伟; 马晓峰; 王青; 于德新; 李笃民; 崔凤玉; 李传福

    2007-01-01

    目的 探讨多层螺旋CT(MSCT)血管成像在诊断大动脉炎中的临床应用价值.方法 对临床拟诊大动脉炎的14例患者进行MSCT血管成像,扫描范围自颈2椎体水平至耻骨联合水平,图像后处理方法包括多平面重组、最大密度投影、容积重组、血管内镜及血管分析,充分显示受累血管的部位、范围及程度.结果 14例患者CT表现为不同程度的动脉管壁增厚,管腔狭窄或闭塞,管腔狭窄具有向心性的特点,部分伴狭窄后扩张.按管腔情况包括狭窄-阻塞型8例,混合型6例.重组图像结合轴面图像观察,可以清晰显示受累大血管及其分支血管的狭窄程度或闭塞情况以及侧支血管形成情况.依据Lupi-Herrea分类法包括Ⅰ型5例,Ⅱ型2例,Ⅲ型6例,Ⅳ型1例,CT结果均与其临床表现相符.结论 MSCT血管成像同时显示大动脉炎的管腔情况和管壁改变,后者对于早期诊断及治疗、改善预后具有重要意义,可以作为此病的首选检查方法.

  19. Eigenvalues of collective emission in multi-slice slab configurations

    Energy Technology Data Exchange (ETDEWEB)

    Friedberg, Richard [Department of Physics, Columbia University, New York, NY 10027 (United States); Manassah, Jamal T. [HMS Consultants, Inc., PO Box 592, New York, NY 10028 (United States)], E-mail: jmanassah@gmail.com

    2008-06-02

    We compute the eigenmodes of collective emission from multi-slice slab configurations, using the transfer matrix formalism. We elucidate within this formalism the phenomena of 'Invisible Gaps' in multiple-slice configuration and of 'Precocious Superradiance' in periodic structures previously observed in numerical solutions of Maxwell-Bloch equations.

  20. 多层螺旋CT门静脉成像对门静脉高压症的诊断及分类价值%Evaluation of the Diagnosis and Classification of Portal Hypertension on Multi-slice Spiral CT Portal Venography

    Institute of Scientific and Technical Information of China (English)

    梁萍; 方华盛; 陈更瑞

    2015-01-01

    Objective Discussion on classification and diagnostic value of multi-slice spiral CT portography (CTPV) on portal hypertension (PHT). Methods A total of 42 patients with PHT, 26 cases of intrahepatic PHT, both in patients with liver cirrhosis, and hepatocellular carcinoma in 7 cases,3 cases of intrahepatic portal vein tumor thrombosis;before the liver of PHT13patients, including 3 cases of portal vein thro mbosis in 4 cases of outer segment, portal vein tumor thrombus in 6 cases of outer segment,cavernous transformation, liver after PHT Budd Chiari syndrome in 3 cases; underwent imaging of 64 slice spiral CT portal, MIP, VR,MPR or CPR reconstruction using volume data, observation of portal vein branches, collateral circulation, characteristics of imaging. Results CTPV can clearly show the initial distribution, evaluating collateral circulation of portal hypertension degree and position classification. Conclusion CTPV can accurately diagnose PHT and differential classification, have important significance to establish prediction of its complications, operation scheme.%目的:探讨多层螺旋CT门静脉成像(CTPV)对门静脉高压症(PHT)的诊断及分类价值。方法收集42例PHT,肝内性PHT 26例,均为肝硬化患者,合并肝癌7例,门静脉肝内分支癌栓形成3例;肝前性PHT13例,其中门静脉肝外段血栓3例,门静脉肝外段癌栓4例,海绵样变6例;肝后性PHT3例,为布加综合征患者;均行64层螺旋CT门静脉成像检查,容积数据采用MIP、VR、MPR或CPR重建,观察门静脉、属支及侧支循环的影像学特征。结果 CTPV能清楚显示侧支循环的分布范围、初步评估门静脉高压程度及部位分类。结论 CTPV能准确诊断PHT及鉴别分类,对预测其并发症、手术方案的制定具有重要的指导意义。

  1. Diagnostic study of multi-slice spiral CT 3D reconstruction and virtual endoscope technology on diagnosing ear temporal diseases%多层螺旋CT三维重建及仿真内镜技术对耳颞部疾病的诊断研究

    Institute of Scientific and Technical Information of China (English)

    张金玲; 李延皎; 陈鹏; 王海波; 李金平; 刘白鹭

    2012-01-01

    Objective To investigate the diagnostic value of multi-slice spiral CT (MSCT) 3D reconstruction and virtual endoscope technology on ear temporal diseases.Methods One hundred and forty patients suspected with ear temporal diseases were examined with MSCT,and all the scanned images were 3D reconstructed and processed by virtual endoscopy.Results In 140 patients,97 cases were detected with ear temporal disease,including 58 cases with acute and chronic otitis media,20 cases with artificially cochlear placement evaluation,2 cases with concha and middle ear malformations and 17 cases with temporal bone injury.MSCT 3D reconstruction and virtual endoscope technology could clearly show the location,scope and form of the lesions and structure relationships with nearby tissues.Conclusions MSCT 3D reconstruction and virtual endoscope technology have important value on diagnosing ear temporal diseases.%目的 探讨多层螺旋CT (MSCT)三维重建及仿真内镜技术对耳颞部疾病的诊断价值.方法 对140例怀疑有耳颞部疾病患者行颞骨MSCT检查,对所有扫描图像进行三维重建及仿真内镜处理.结果 140例患者中97例检出耳颞部疾病,其中58例急、慢性中耳炎,20例人工耳蜗植入术前进行评价,2例外中耳部发育畸形,17例颞骨外伤.MSCT三维重建及仿真内镜技术能够清晰显示病变的位置、范围、形态及与周围组织结构的关系.结论 MSCT三维重建及仿真内镜技术对耳颞部疾病的诊断具有重要价值.

  2. 多层螺旋CT小肠造影在结肠受累克罗恩病患者诊断中的价值%The clinical value of multi-slice CT enterography in diagnosis of Crohn disease involving colon

    Institute of Scientific and Technical Information of China (English)

    丰萍璐; 程建美; 吴兴旺; 胡乃中

    2015-01-01

    Objective To analyze the clinical,endoscopic,histological and multi-slice CT enterography(MSCTE)characteristics of Crohn disease(CD),and to explore the value of MSCTE in the diagnosis of CD involving the colon. Methods Clinical,endoscopic,histo-logical and MSCTE data of 71 patients with CD attending in our hospital from January 2009 to September 2013 were analyzed,and the data of 28 patients with ITB as a control at the same period were studied. The parameters for diagnosis of CD were screened by logistic regression a-nalysis. Results The incidence rates of diarrhea,perianal disease and C-reaction protein elevated in CD were higher than those in intestinal tuberculosis(ITB);the occurrence rate of history of abenteric tuberculosis,and the positive rates of PPD and T-SPOT were lesser than those of ITB(P0. 05). The pathological analysis showed that non-caseous granulomas,fissure-like ulcers,crypt abscess and caseous granulomas between the two groups had no statistically significant difference (P>0. 05 ). The analysis of MSCTE imaging showed that mural stratification enhancement,thickening obviously of the membrane margin and comb sign occurred more frequently in CD than in ITB and that Lymph node calcification or central necrosis was more frequently found in ITB than in CD. The results of logistic regression anal-ysis showed that thickening obviously of the membrane margin(OR=5. 140,95%CI:1. 053~25. 087)was an independent predictor for the diagnosis of CD. Conclusion CD has clinical,colonoscopic and pathological characteristics,but the diagnostic value of these characteristics is limited,and the comprehensive judgment can not meet the demand of clinical diagnosis. Application of MSCTE is helpful to improve the level of diagnosis of CD.%目的:分析结肠受累克罗恩病(CD)的临床、内镜、病理及多层螺旋CT小肠造影(MSCTE)特征,探讨MSCTE在CD诊断中的临床价值。方法选择结肠受累CD住院患者71例,选取同期28

  3. Establishment of multi-slice computed tomography (MSCT) reference level in Johor, Malaysia

    Science.gov (United States)

    Karim, M. K. A.; Hashim, S.; Bakar, K. A.; Muhammad, H.; Sabarudin, A.; Ang, W. C.; Bahruddin, N. A.

    2016-03-01

    Radiation doses from computed tomography (CT) are the highest and most hazardous compared to other imaging modalities. This study aimed to evaluate radiation dose in Johor, Malaysia to patients during computed tomography examinations of the brain, chest and abdomen and to establish the local diagnostic reference levels (DRLs) as are present with the current, state- of-art, multi-slice CT scanners. Survey forms were sent to five centres performing CT to obtain data regarding acquisition parameters as well as the dose information from CT consoles. CT- EXPO (Version 2.3.1, Germany) was used to validate the dose information. The proposed DRLs were indicated by rounding the third quartiles of whole dose distributions where mean values of CTDIw (mGy), CTDIvol (mGy) and DLP (mGy.cm) were comparable with other reference levels; 63, 63, and 1015 respectively for CT Brain; 15, 14, and 450 respectively for CT thorax and 16, 17, and 590 respectively for CT abdomen. The study revealed that the CT practice and dose output were revolutionised, and must keep up with the pace of introductory technology. We suggest that CTDIvol should be included in current national DRLs, as modern CTs are configured with a higher number of detectors and are independent of pitch factors.

  4. The value of multi-slice spiral CT enterography and double-balloon enteroscopy in the diagnosis of unexplained abdominal pains%多层螺旋CT小肠造影与双气囊小肠镜在不明原因腹痛诊断中的价值

    Institute of Scientific and Technical Information of China (English)

    周建伟; 潘杰; 侯俊良

    2012-01-01

    Objective To assess the value of multi-slice spiral CT enterography (MSCTE) and double-balloon enteroscopy (DBE) in the diagnosis of unexplained abdominal pains. Methods 41 patients with unexplained abdominal pains were selected and received MSCTE and DBE examination. With combining the results of endoscopy and/or surgical pathology, clinical follow-ups, the differences in pathological detection rate and diagnostic accuracy between these two measures were compared. Results The detection rates of MSCTE and DBE were 63.41% (26/41) and 87.80% (36/41), and the diagnostic accuracies were 70.73% (29/41) and 92.68% (38/41), respectively. Conclusion The detection rate and diagnostic accuracy of DBE were both higher than those of MSCTE. MSCTE could facilitate the diagnosis of small bowel tumor and Crohn's disease, with positioning and qualitative value. MSCTE could be a pre-test to help decide the appropriate way of DBE insertion.%目的:评价多层螺旋CT小肠造影(MSCTE)与双气囊小肠镜(DBE)在不明原因腹痛患者诊断中的价值.方法:41例不明原因腹痛患者,同时行MSCTE和DBE检查,结合内镜和(或)手术病理、临床随访等,比较两者对不明原因腹痛病因的检出率、诊断准确率.结果:MSCTE和DBE的病变检出率分别为63.41%(26/41)和87.80%(36/41);诊断准确率分别为70.73%(29/41)和92.68%(38/41).结论:DBE对不明原因腹痛患者的病变检出率、诊断准确率均高于MSCTE; MSCTE对小肠肿瘤、克罗恩病有一定的定位、定性诊断价值;MSCTE可作为DBE检查前筛选性检查,对DBE进镜方式选择提供有效的帮助.

  5. Correlation study of multi-slice spiral CT perfusion imaging in liver cirrhosis and portal morphology%肝硬化多层螺旋CT灌注成像及与门静脉形态学的相关研究

    Institute of Scientific and Technical Information of China (English)

    肖平; 娄明武; 谭理连; 李扬彬; 李泳; 高立; 林焕兴

    2009-01-01

    Objective To discuss correlation of hemodynamic changes and portal vein diameter with multi-slice spiral CT peffusion imaging in liver cirrhosis. Method 31 cases liver cirrhosis were enrolled in this study. The first porta hepatis were selected for target lay of CT perfusion scan. Liver perfusion parameters were obtained by color perfusion map method. Right to left diameter and occipitofrontal diame-ter of portal vein were measured. 30 cases of normal persons were used as control group. Result Hepatic arterial perfusion (HAP) in liver 0.05). Hepatic perfusion index (HPI) were (19.13±3.33)% and (20.61±8.56)%, which had no statistically significant difference with the other two groups (P>0.05). Conclusion Multi-spiral CT perfnsion imaging is an effectively noninvasive method to evaluate the hemodynamic changes of liver cirrhosis. Occipitofrontal diameter of portal vein with liver cirrhosis can reflect the state of liver hemodynamics.%目的 利用多层CT灌注成像探讨肝硬化血流灌注变化及与门静脉径线的相关性.方法 肝硬化31例,选取第一肝门层面作为CT灌注扫描靶层面,采用彩色灌注图法获得各肝脏灌注参数并对门静脉径线进行均值测量;30例正常人作对照组.结果 正常组与肝硬化组肝脏灌注参数分别为:肝动脉灌注量(HAP)(24.80±5.84)、(19.49±7.30)ml/(min·100ml),门静脉灌注量(PVP)(104.91±21.70)、(79.17±23.05)ml/(min·100ml),总肝灌注量(TLP)(129.90±25.19)、(98.67±22.74)ml/(min·100ml),2组比较,差异均有统计学意义(P0.05).肝硬化患者的TLP与门静脉前后径呈负相关(r=-0.46,P<0.05).结论 多层螺旋CT灌注成像是评价肝硬化血流灌注变化的一种有效的非创伤性的检查方法.肝硬化时门静脉前后径的变化反映其肝脏血流灌注状况.

  6. 多层螺旋CT(MSCT)灌注评估糖尿病肾病患者肾功能的临床研究%Clinical Study on Multi-slice Spiral CT (MSCT) in Evaluation of Renal Function in Patients with Diabetic Nephropathy

    Institute of Scientific and Technical Information of China (English)

    刘乃全; 孙广萍

    2016-01-01

    Objective To investigate the clinical value of multi-slice spiral CT (MSCT) perfusion in evaluation of renal function in patients with diabetic nephropathy (DN). Methods 31 cases of patients with clinically diagnosed DN and 26 normal volunteers were selected as the study subjects. All of them underwent bilateral renal perfusion scan with 64 slice spiral CT. The relationship between renal cortical perfusion parameters and clinical examination indicators in the two groups was compared. The changes in clinical examination indicators before and after perfusion scan were analyzed.Results The renal blood flow (BF), renal blood volume (BV) and renal permeability surface (PS) in DN group were significantly lower than those in control group. The mean transit time (MTT) of renal contrast agent was significantly longer than that of control group (P<0.05); BF, BV, MTT, PS and microalbumin, 24h urinary protein quantitation, creatinine and fasting blood glucose were correlated. BF and BV had no correlation (P<0.05).Conclusion MSCT renal perfusion parameters and microalbumin, 24h urinary protein quantitation and fasting blood glucose have certain correlation, which can be used for evaluation of renal function damage in patients with DN.%目的:探讨多层螺旋CT(MSCT)灌注评估糖尿病肾病(DN)患者肾功能的临床价值。方法选取31例临床确诊为DN患者及26例正常志愿者作为研究对象,均行64层螺旋CT双侧肾脏灌注扫描,对比两组肾皮质灌注参数与临床检验指标的关系,分析灌注扫描前后临床检验指标变化。结果 DN组肾血流量(BF)、肾血容量(BV)、脏表面通透性(PS)均明显低于对照组,肾造影剂的平均通过时间(MTT)明显高于对照组(P<0.05);BF、BV、MTT、PS与微量白蛋白、24h尿蛋白定量、肌酐、空腹血糖存在相关性,BF、BV与肌酐存在相关性(P<0.05)。结论 MSCT肾脏灌注指标与微量白蛋白、24h尿蛋白定量、空腹血糖具有一定相

  7. Clinical value of multi-slice spiral CT perfusion imaging in evaluation of the interventional therapy of lung cancer%多层螺旋CT灌注成像评价肺癌介入治疗效果的临床应用价值

    Institute of Scientific and Technical Information of China (English)

    殷好治; 梁付奎; 傅晓琴; 伦俊杰; 刘明标

    2012-01-01

    目的 研究多层螺旋CT灌注成像评价肺癌介入治疗效果的临床应用价值.方法 选择50例中晚期肺癌病人,介入治疗前及治疗后1个月行灌注扫描,对瘤体中心层面进行动态灌注扫描,计算血流量(BF)、血容量(BV)、平均通过时间(MTT)、毛细血管表面通透性(PS),比较介入治疗前后各项灌注参数的变化,3个月后行常规CT检查观察肿瘤大小有无变化.结果 35例肺癌介入治疗后,肿瘤BF、BV降低,MTT显著升高(差异有统计学意义,P<0.05),但PS 变化不明显(P>0.05),3个月后随访观察瘤体组织出现不同程度缩小;15例肺癌BF、BV、MTT、PS均无明显变化(P>0.05),3个月后随访观察瘤体显示不同程度增大或无明显变化.结论 MSCT灌注成像参数变化可早期判断和预测治疗肺癌介入治疗效果.%Objective To evaluate the clinical value of multi-slice spiral CT(MSCT) perfusion imaging in vealuation of the interventional therapy of lung cancer. Methods Fifty patients with advanced lung cander were involved in the study. All patients underwent MSCT perfusion scanning preoperatively and postoperatively in one month, which was focused on the central area of lesions. The pre- and post-operative factors including tissue blood flow(BF) , blood volume(BV) , mean transit time(MTT) and vascular permeability surface (PS) were compared. The volume changes of the lesions 3 months after the intervention were obtained by conventional CT scanning. Results After interventional therapy, the BF and BV in 35 patiens significantly reduced, while MTT rised(P0. 05) ,the volumes of lesions reduced after 3 months. In 15 patiens,BF,BV,MTT and PS showed no significant variation (P>0. 05) , the lesion's volume increased or had no significant changes after 3 months. Conclusion MSCT perfusion imaging can earlier evaluate the therapeutic effect on the intervention of advanced lung cancer.

  8. The correlation between periodontal diseases and carotid arteries atherosclerosis by three-dimensional reconstruction technique of multi-slice spiral CT in elderly people%三维CT成像评价老年人牙齿残缺与颈动脉粥样硬化的关系

    Institute of Scientific and Technical Information of China (English)

    王瑾; 刘海霞; 孙静华; 付英杰

    2013-01-01

    目的 探讨三维CT成像技术显示牙齿残缺的临床应用价值,并通过三维CT成像评价老年人牙齿残缺与颈动脉粥样硬化的关系. 方法 从年龄大于60岁的三维CT血管造影检查者中随机选择60例颈部动脉粥样硬化患者为病例组,颈部动脉正常者60例为对照组,采用多种图像后处理技术,分别观察两组牙齿残缺情况和颈部动脉情况. 结果 病例组患龋人数、缺齿人数、无牙颌人数均多于对照组(P<0.05).牙齿完整人数对照组(19例)高于病例组(7例),患龋者病组(7.3±3.0)颗高于对照组(6.0±2.1)颗,缺齿者均数病例组(45例)高于对照组(39例)(P<0.05);牙齿疾患与颈动脉粥样硬化疾病相关,三维CT成像技术观察颌骨牙齿情况,可以全面展示牙齿立体形态和内部结构,为牙周疾病提供有价值的资料. 结论 老年人龋齿、牙缺失与动脉粥样硬化密切相关.三维CT成像技术可为研究外周血管疾病与牙周疾病提供有价值的方法.%Objective To explore the possible correlation between periodontal disease and carotid arteries atherosclerosis in old people,and to study the diagnostic value for periodontal disease using three-dimensional (3D) reconstruction technique of multi-slice spiral CT (MSCT).Methods Patients underwent multi-detector row CT angiography with carotid arteries atherosclerosis (control group) and without carotid arteries atherosclerosis (case group) were evaluated with the stereoscopic configuration of teeth,and the number of decayed teeth and lost teeth were recorded.Results Bythe 3D reconstruction technique,the number of decayed teeth and lost teeth between two groups were significantly different (P<0.05).The number of dental integrity patients was higher in control group (19 cases) than in case group(7 cases).The mean of dental caries was higher in control group(7.3±3.0) than in case group(6.0±2.1).The mean of hypodontia was higher in control group(45 cases) than

  9. 多层螺旋CT及多维重建技术对隐匿性肋骨骨折的诊断价值探讨%Study of the multi-slice CT and for multi-dimensional reconstruction techniques the diagnosis of occult rib fracture

    Institute of Scientific and Technical Information of China (English)

    蔡洪涛

    2014-01-01

    目的:考察多层螺旋CT(MSCT)联合多维重建技术对隐匿性肋骨骨折的临床诊断价值,为该类疾病临床诊断提供参考。方法:以我院2012年7月至2014年2月间收治的73例隐匿性肋骨骨折患者为研究对象,使用MSCT联合VR、SSD、CRP等多种重建技术对患者进行检查,统计并分析影像学检查结果。结果:73例患者经MSCT检查确诊隐匿性肋骨骨折107处,骨折多发于肋骨角(59.81%)且以非完全线性骨折为主(91.59%)。所用多维重建技术的诊断精度依次为:CRP(100.0%)>MPR(97.19%)>SSD(85.89%)>VR(78.50%)>MIP(27.88%)。结论:MSCT联合多维重建技术对隐匿性肋骨骨折具有较为明确的诊断价值,MSCT与CRP/MPR及VR等联用可获得较为理想的诊断率。%Objective:To investigate the clinical value of the multi-slice CT and for multi-dimensional reconstruction techniques the diagnosis of occult rib fracture, to provide a reference for the diagnosis of occult rib fracture.Methods:73 cases patients with occult rib fracture which received treatment during 2012.07 to 2014. 02, were the objects for this study, used MSCT joint VR, SSD, CRP and other reconstruction techniques to detected the occult rib fracture of all the patients, and then the imaging results of the patients were analyzed. Results:The results of MSCT showed 107 occult rib fracture were detected for 73 cases patients, and about 59.81% occult rib fracture were occurred in the rib angle, and the non- fully linear fracture dominated 91.59%. The diagnostic accuracy of all the multi-dimensional reconstruction techniques used in this study were: CRP (100.0%)> MPR (97.19%)>SSD (85.89%)> VR (78.50%)> MIP (27.88%).Conclusions:The MSCT joint multi-dimensional reconstruction techniques has a speciifc diagnostic value for the occult rib fractures, MSCT combined with MSCT CRP / MPR and VR, etc. could received a ideal diagnostic accuracy.

  10. 前后交叉韧带及半月板损伤的MDCT与关节镜的对比研究%Comparative study between multi-slice spiral CT and knee arthroscopy in diagnosis of anterior and posterior cruciate ligament injury and meniscus injury

    Institute of Scientific and Technical Information of China (English)

    黄瑞庭; 刘玉涛; 张德佳; 杜中立; 张应鹏; 郭宗义; 黄海松

    2013-01-01

    目的 探讨多层螺旋CT在膝关节外伤中前后交叉韧带与半月板损伤的诊断价值.方法 回顾性分析45例经膝关节镜证实的前后交叉韧带和半月板损伤的多层螺旋CT直接征象和间接征象.结果 前后交叉韧带损伤的直接征象表现为韧带断裂、密度欠均匀,韧带附着点撕脱性骨折,间接征象表现为韧带肿胀,周围脂肪间隙模糊欠清;半月板损伤的MDCT直接征象是形态失常、密度不均匀及裂隙征,间接征象是膝关节滑膜增厚、关节囊关节腔内积液、损伤的半月板周围软组织肿胀等.45例患者中,MDCT显示前交叉韧带损伤14例(14/20),后交叉韧带损伤11例(11/15),内侧半月板损伤8个(8/12),外侧半月板损伤12个(12/20),交叉韧带与半月板同时损伤10例,韧带附着点及胫骨平台骨折18例.结论 多层螺旋CT在膝关节外伤中的前后交叉韧带及半月板的损伤有一定的诊断价值,可为缺少磁共振设备的基层医院提供一有用的检查方法.%Objective To evaluate the diagnotic value of multi-slice spiral CT(MDCT) in anterior and posterior cruciate ligament injury and meniscus injury. Methods Retrospective analysis of the CT direct signs and indirect signs in 45 cases diagnosed with anterior and posterior cruciate ligament injury and meniscus injury confirmed by knee arthroscopic was conducted. Results MDCT findings of the direct signs of the anterior and posterior cruciate ligament injury included the ligament rupture, less uniform density, ligament attachment points avulsion fracture. Indirect signs included ligament swelling, fuzzy around the fat space less clear; MDCT findings of the direct signs of the meniscus injury included morphological disorders, uneven density and broken sign. Indirect signs included thickening of the synovium, joint capsule effusion, soft tissue swelling of the injuryed meniscus. In 45 patients, MDCT showed the anterior cruciate ligament injury in 14 cases (14

  11. Clinical Applications of FDG PET and PET/CT in Head and Neck Cancer

    Directory of Open Access Journals (Sweden)

    Akram Al-Ibraheem

    2009-01-01

    Full Text Available 18F-FDG PET plays an increasing role in diagnosis and management planning of head and neck cancer. Hybrid PET/CT has promoted the field of molecular imaging in head and neck cancer. This modality is particular relevant in the head and neck region, given the complex anatomy and variable physiologic FDG uptake patterns. The vast majority of 18F-FDG PET and PET/CT applications in head and neck cancer related to head and neck squamous cell carcinoma. Clinical applications of 18F-FDG PET and PET/CT in head and neck cancer include diagnosis of distant metastases, identification of synchronous 2nd primaries, detection of carcinoma of unknown primary and detection of residual or recurrent disease. Emerging applications are precise delineation of the tumor volume for radiation treatment planning, monitoring treatment, and providing prognostic information. The clinical role of 18F-FDG PET/CT in N0 disease is limited which is in line with findings of other imaging modalities. MRI is usually used for T staging with an intense discussion concerning the preferable imaging modality for regional lymph node staging as PET/CT, MRI, and multi-slice spiral CT are all improving rapidly. Is this review, we summarize recent literature on 18F-FDG PET and PET/CT imaging of head and neck cancer.

  12. Diagnostic value of multi-slice spiral CT post-processing technique on sacroiliac joint lesions in patients with ankylosing spondylitis%多层螺旋CT后处理技术在强直性脊柱炎骶髂关节病变中的诊断价值

    Institute of Scientific and Technical Information of China (English)

    亓立勇

    2012-01-01

    Objective To investigate the diagnostic value of multi-slice spiral CT(MSCT) and its multi-planar reconstruction(MPR) and curved planar reconstruction(CPR) on sacroiliac joint with ankylosing spondylitis(AS).Methods Fifty-six patients with AS proved clinically were examined and analyzed with MSCT and reconstruction.Then the CT manifestations of sacroiliace joints were analyzed.And choose a sagittal image respectively in the margin of the sacrum one-four,one-second and two-four.Then went down the sacrum line trace for CPR technique get double sided sacroiliac joint imaging.The images,MPR transect images and CPR image were analyed.Results Early CT findings included coarsearticular surface,interrupted jiont cortex,vague articular face,subcortical microcysts and sclerotic articular surface,while jiont space was normal.CT findings in progressive stage were uneven articular surface,damaged bony cortex,subcartilaginous bone microcyats,obviously sclerotic articular surface,extended jiontspace.In stable stage,CT findings included joint ankylosis,articular space dsiappearance,and sacroiliac ligament calcification.Fifty-six cases of AS patients,bilateral simultaneous involvement in 47 cases,unilateral involvement in 9 cases,axial image diagnosis,Ⅰ-Ⅱ grade 16 cases,Ⅲ-Ⅳ grade 26 cases.MPR image diagnosis of Ⅰ-Ⅱ grade 24 cases,Ⅲ-Ⅳ Grade 26 cases,CPR class Ⅰ diagnostic images-Ⅱ grade 29 cases,Ⅲ-Ⅳ grade in 26 cases,early diagnosis of axial images and reconstruction images were significantly different (P < 0.05),the late diagnosis rates were not significantly different (P > 0.05).Conclusions It is valuable to use MPR and CPR images to diagnosis sacroiliac joint lesions in patients with ankylosing spondylitis.Especially CPR image can be used to comprehensively observe sacroiliac joint,and it is more meaningful in early diagnosis of sacroiliac joint lesions in patients with AS.%目的 探讨多层螺旋CT(MSCT)多平面重组(MPR)技术和曲面重组(CPR

  13. Detecting anomalous traders using multi-slice network analysis

    Science.gov (United States)

    Sun, Xiao-Qian; Shen, Hua-Wei; Cheng, Xue-Qi; Zhang, Yuqing

    2017-05-01

    Manipulation is an important issue for both developed and emerging stock markets. Many efforts have been made to detect manipulation in stock market. However, it is still an open problem to identify the fraudulent traders, especially when they collude with each other. In this paper, we focus on the problem of identifying anomalous traders using the transaction data of 8 manipulated stocks and 42 non-manipulated stocks during a one-year period. For each stock, we construct a multi-slice trading network to characterize the daily trading behavior and the cross-day participation of each trader. Comparing the multi-slice trading network of manipulated stocks and non-manipulated stocks with their randomized version, we find that manipulated stocks exhibit high number of trader pairs that trade with each other in multiple days and high deviation from randomized network at correlation between trading frequency and trading activity. These findings are effective at distinguishing manipulated stocks from non-manipulated ones and at identifying anomalous traders.

  14. Development of Multi-slice Analytical Tool to Support BIM-based Design Process

    Science.gov (United States)

    Atmodiwirjo, P.; Johanes, M.; Yatmo, Y. A.

    2017-03-01

    This paper describes the on-going development of computational tool to analyse architecture and interior space based on multi-slice representation approach that is integrated with Building Information Modelling (BIM). Architecture and interior space is experienced as a dynamic entity, which have the spatial properties that might be variable from one part of space to another, therefore the representation of space through standard architectural drawings is sometimes not sufficient. The representation of space as a series of slices with certain properties in each slice becomes important, so that the different characteristics in each part of space could inform the design process. The analytical tool is developed for use as a stand-alone application that utilises the data exported from generic BIM modelling tool. The tool would be useful to assist design development process that applies BIM, particularly for the design of architecture and interior spaces that are experienced as continuous spaces. The tool allows the identification of how the spatial properties change dynamically throughout the space and allows the prediction of the potential design problems. Integrating the multi-slice analytical tool in BIM-based design process thereby could assist the architects to generate better design and to avoid unnecessary costs that are often caused by failure to identify problems during design development stages.

  15. Multi-slice CT diagnosis of anomaly of ostiomeatal complex and chronic sinusitis%多螺旋 CT检测在窦口-鼻道复合体解剖变异与慢性鼻窦炎中的应用

    Institute of Scientific and Technical Information of China (English)

    刘景旺; 蒋守芳

    2014-01-01

    Objective To study the incidence of anomaly of ostiomeatal complex ( OMC) and its relation to chronic sinusi-tis.Methods CT images of 933 cases who received health examination were retrospectively analyzed .The anatomical variants of OMC were clearly displayed by MPR .Variants of middle turbinate recurvation/gasification , ethmoidal bulla excessive gasi-fication,uncinate process diviation/hypertrophy/gasification,agger excessive gasification,and Haller cell were observed and compared in order to search the relation between anomaly and sinusitis .Results In the 933 cases,the incidence of chronic si-nusitis was 30.12%,with chronic genyantritis being the highest .The incidences of OMC anomaly were 1.7%,13.8%,5.8%, 6.8%,5.1%,1.1%,0.4%,and 2.7%respectively.OMC anomaly in chronic genyantritis ,ethmoidal sinusitis and frontal si-nusitis showed significant differences (P<0.01).The incidence of nasosinusitis in the mixed anomaly group was remarkably higher than the single anomaly group .In 457 cases of non-smokers,OMC anomaly was significantly related to the incidence differences of chronic genyantritis ,ethmoidal sinusitis and frontal sinusitis (P<0.05).In terms of single anomaly factors,mid-dle turbinate recurvation ,uncinate process gasification/diviation/hypertrophy were closely related to the incidence of chronic genyantritis;ethmoidal bulla excessive gasification was closely related to chronic ethmoidal sinusitis ;uncinate process diviation was closely related to chronic frontal sinusitis .Conclusion 1.Multi-slice CT can clearly show the anomaly of OMC .2.Differ-ent anomalies of OMC play different roles in the development of chronic sinusitis .%目的:应用多螺旋CT检测窦口-鼻道复合体( OMC)解剖变异发生率及探讨其与慢性鼻窦炎发生的关系。方法回顾性分析本院933例健康查体者鼻窦扫描图像,薄层横断图像重建冠状面图像,观察OMC解剖变异情况:中鼻甲(反曲、气化)、筛泡过度气化、

  16. A study of the relationship between the portal vein thrombosis and clinical progression in portal hypertension on multi-slice CT portal venography%MSCT门静脉成像对门脉高压症中门静脉血栓形成与临床病情关系的研究

    Institute of Scientific and Technical Information of China (English)

    王克扬; 贺文; 赵丽琴

    2012-01-01

    目的:采用64排螺旋CT门静脉成像探讨肝硬化(LC)门脉高压症(PH)门静脉血栓(PVT)形成对临床病程进展的影响.方法:对183例LC患者行CT检查,其中并发PVT者109例,无血栓者74例,应用MIP、MPR、CPR方法多角度多层面显示门静脉系统血管结构和侧支循环,测量血栓范围和狭窄程度.分别比较PVT组和对照组之间、不同Child-Pugh(CP)分级亚组间的肝功能、凝血功能、门脉系统血管宽度、侧支循环、脾脏大小的差异,分析PVT组各影像特之间及其与肝功能的相关性.结果:PVT组与对照组间的血清总胆红素、门静脉和脾静脉宽度、脾面积、脾/胃-肾分流的差异均有统计学意义(t=-2.830、P=0.005;t=3.576、P0.05);前腹壁静脉曲张在各分级中差异均有统计学意义(χ2=4.485,P=0.034).PVT组肠系膜上静脉血栓与肠壁水肿有一定的相关性(r=0.227,P=0.018);脾静脉与胃左静脉宽度有一定的相关性(r=0.371,P<0.001).结论:门静脉血栓形成与门脉高压症病情密切相关,可能为促进肝硬化临床病程发展的重要因素.%Objective: To investigate the effect of the portal vein thrombosis (PVT) on disease progression of liver cirrhosis (LC) portal hypertension (PH) using CT portal venography (CTPV). Methods:183 patients with LC,divided into PVT group (n = 109) and control group (n = 74) ,were performed by multi slice CT (MSCT). MIP,MPR and CPR were used to display the portal venous system and collateral circulations,and to measure the thrombosis as well as stenosis. The liver function,coagulation function,the imaging features of portal veins and PVT were compared between these two groups, then in different Child Pugh (CP) classifications. Results. There were significant differences between the two groups in total serum bilirubin,the width of main portal vein (MPV) and spleen vein (SPV),sectional area of spleen,splenic or gastric re nal shunt (t = - 2. 830,P = 0. 005 ; t=3. 576,P<0. 001;t=0. 780

  17. Diagnostic value of CT enhancement scanning and post-processing technique with multi-slice spiral CT in the bladder cancers%多层螺旋CT 增强扫描及后处理成像在膀胱癌诊断中的价值

    Institute of Scientific and Technical Information of China (English)

    刘本波; 张新炎; 张燕; 夏海泓; 初迎幸

    2014-01-01

    Objective To discuss the diagnostic value of enhancement scanning combined with post-processing imaging technique with spiral CT in the bladder cancers .Methods Thirty-six patients with bladder cancers were diagnosed by pathological findings ,all of whom were examined by enhancement scanning .The data were transfer to workstation ,the multi-planar reconstruction and virtual endoscopy were progressed ,the characteristics of CT images were observed .The results were compared with pathological findings in a double-blind mode .Results 24 cases of tumor were located on the trigone of urinary bladder ,5 cases on the right side and 7 cases on left side .The sensitivity of the axial ,MPR and CTVE images in detecting bladder cancers were 97 .2% ,94 .4% ,95 .7% respectively .The axial image offered enough intramural and extravesical information ,MPR can directly demonstrate the origin of the lesion and relation with the ureter ,CTVE can display the surface morphology of the tumor ,and relationship with ureteric orifices .Conclusion CT enhanced scan-ning axial images combined with multi-planar reconstruction and virtual endoscopy are of great value on diagnosis of blad-der cancer .%目的:探讨螺旋CT增强扫描结合后处理成像技术在膀胱癌中的诊断价值。方法分析经手术病理证实为膀胱癌的患者36例,术前均行螺旋C T增强扫描,将原始容积数据传至工作站,进行多平面重建(M PR )、仿真内镜成像(VE),观察其CT影像特点,采用双盲对比,与病理结果对照分析。结果肿瘤位于膀胱三角区24例,右侧壁5例,左侧壁7例。轴位、MPR及CTVE在探测膀胱肿瘤的敏感性分别为97.2%,94.4%,95.7%,增强轴位图像能够提供丰富的膀胱壁内外信息,M PR能够直接显示肿瘤起源和膀胱外侵犯及与输尿管的关系,V E可以显示肿瘤表面形态及和输尿管开口关系。结论螺旋CT增强扫描轴位图像结合MPR和CTVE成像

  18. Solitary pulmonary nodules: comparison of multi-slice computed tomography perfusion study with vascular endothelial growth factor and microvessel density

    Institute of Scientific and Technical Information of China (English)

    BAI Rong-jie; CHENG Xiao-guang; QU Hui; SHEN Bao-zhong; HAN Ming-jun; WU Zhen-hua

    2009-01-01

    Background The solitary pulmonary nodule (SPN) is one of the most common findings on chest radiographs. The objectives of clinical practice are to differentiate malignant nodules from benign nodules in the least invasive way and to make a specific diagnosis. This study was aimed to evaluate the correlation between perfusion imaging features and microvessel density (MVD) and vascular endothelial growth factors (VEGF) in SPNs using multi-slice computed tomography (MSCT); and to provide the theoretical basis for SPN blood flow pattern and blood flow quantitative features.Also, the study called for the discussion of the method's clinical application value in the differential diagnosis of benign and malignant SPNs.Methods Sixty-eight patients with SPN underwent multi-location dynamic contrast enhanced (nonionic contrast material was administrated via the antecubital vein at a rate of 4 ml/s) MSCT. Precontrast and postcontrast attenuations on every scan was studied. Perfusion, peak height, and the ratio of the peak height of the SPN to that of the aorta were analyzed. Perfusion was calculated using the maximum gradient of the time-density curves (TDC) and the peak height of the aorta. The quantitative parameters (perfusion, peak height, ratio of peak height of the SPN to that of the aorta) of the blood flow pattern were compared with MVD and the VEGF expression of immunohistochemistry.Results The perfusion peak heights of malignant ((96.15±11.55) HU) and inflammatory ((101.15±8.41) HU) SPNs were significantly higher than those of benign ((47.24±9.15) HU) SPNs (P<0.05, P<0.05). Ratios of SPN-to-aorta of malignant and inflammatory SPNs were significantly higher than those of benign SPNs (P<0.05, P<0.05). No significant differences were found between the peak height and SPN-to-aorta ratio of malignant SPNs and inflammatory SPNs (P>0.05, P>0.05). The precontrast densities of inflammatory SPNs were lower than those of malignant SPNs (P<0.05).Perfusion values

  19. Multi-Slice Magnetic Resonance Imaging with the Dynamic Multi-Coil Technique

    Science.gov (United States)

    Juchem, Christoph; Nahhass, Omar M.; Nixon, Terence W.; de Graaf, Robin A.

    2015-01-01

    To date, spatial encoding for MRI is based on linear X, Y and Z field gradients generated by dedicated X, Y and Z wire patterns. We recently introduced the Dynamic Multi-Coil Technique (DYNAMITE) for the generation of magnetic field shapes for biomedical MR applications from a set of individually driven localized coils. The benefits for B0 magnetic field homogenization have been shown as well as proof-of-principle of radial and algebraic MRI. In this study the potential of DYNAMITE MRI is explored further and the first multi-slice MRI implementation is presented in which all gradient fields are purely DYNAMITE-based. The obtained image fidelity is shown to be virtually identical to a conventional MRI system with dedicated X, Y and Z gradient coils. Comparable image quality is a milestone towards the establishment of fully functional DYNAMITE MRI (and shim) systems. PMID:26419649

  20. Multi-slice MRI with the dynamic multi-coil technique.

    Science.gov (United States)

    Juchem, Christoph; Nahhass, Omar M; Nixon, Terence W; de Graaf, Robin A

    2015-11-01

    To date, spatial encoding for MRI is based on linear X, Y and Z field gradients generated by dedicated X, Y and Z wire patterns. We recently introduced the dynamic multi-coil technique (DYNAMITE) for the generation of magnetic field shapes for biomedical MR applications from a set of individually driven localized coils. The benefits for B0 magnetic field homogenization have been shown, as well as proof of principle of radial and algebraic MRI. In this study the potential of DYNAMITE MRI is explored further and the first multi-slice MRI implementation in which all gradient fields are purely DYNAMITE based is presented. The obtained image fidelity is shown to be virtually identical to that of a conventional MRI system with dedicated X, Y and Z gradient coils. Comparable image quality is a milestone towards the establishment of fully functional DYNAMITE MRI (and shim) systems.

  1. 大小肠双充盈法多层螺旋CT肠道成像对炎症性肠病的诊断价值%Multi-slice CT Enterography with Double-iflling Method in Diagnosis of Inlfammatory Bowel Diseases

    Institute of Scientific and Technical Information of China (English)

    刘克昌; 项微微; 张胜兰; 项光涨; 殷焱; 杨国平

    2015-01-01

    Purpose To summarize the imaging features of inflammatory bowel diseases (IBD) with double-filling method using multi-slice CT enterography (MSCTE), and to evaluate the clinical significance of MSCTE in diagnosis of IBD. Materials and Methods MSCTE data with double-filling method of 52 patients with IBD were retrospectively analyzed. 52 IBD patients included 42 cases of Crohn's disease (CD) and 10 cases of ulcerative colitis (UC). Bowel dilatation and lesions display were evaluated. Results Among 52 patients, ileum dilated optimal in 10 cases (19.23%) and good in 42 cases (80.77%); jejunum dilated good in 21 cases (40.38%) and poor in 31cases (59.62%). Exhaustive evaluation for large bowel diseases were good in 50 cases (96.15%). The ileocecal junction displayed well in 52 cases (100.00%). Among the 42 cases of CD, 20 cases (47.62%) had lesions limited in the small intestine, 22 cases (52.38%) had lesions involved both small intestine and colon. Among 10 cases of UC, 9 cases had lesions limited in the colon, and 1 case with the terminal ileum and the colon involved simultaneously. The MSCTE findings of 52 patients included bowel wall thickening and abnormal enhancement in 52 cases, stenosis in 28 cases, increased mesenteric vascularity in 46 cases, enlarged mesenteric lymph nodes in 27 cases, phlegmon in 10 cases, incomplete intestinal obstruction in 4 cases, abscess or inflammatory masses in 7 cases, fistulas in 3 cases, perianal lesion in 12 cases, serous cavity effusion in 15 cases, sacroiliitis in 13 cases, the urinary and biliary stones in 18 cases, and hepatosplenomegaly in 9 cases. Conclusion MSCTE with double-filling method can delineate the wall lesions of small bowels and colons very well, and can also display extraintestinal lesions and complications. It obviously improves the accuracy of localization and qualitative diagnosis on IBD.%目的:总结炎症性肠病(IBD)在大小肠双充盈法多层螺旋CT(MSCT)肠道成像中的影像表现,

  2. Scanning protocol optimization and dose evaluation in coronary stenosis using multi-slices computed tomography

    Science.gov (United States)

    Huang, Yung-hui; Chen, Chia-lin; Sheu, Chin-yin; Lee, Jason J. S.

    2007-02-01

    Cardiovascular diseases are the most common incidence for premature death in developed countries. A major fraction is attributable to atherosclerotic coronary artery disease, which may result in sudden cardiac failure. A reduction of mortality caused by myocardial infarction may be achieved if coronary atherosclerosis can be detected and treated at an early stage before symptoms occur. Therefore, there is need for an effective tool that allows identification of patients at increased risk for future cardiac events. The current multi-detector CT has been widely used for detection and quantification of coronary calcifications as a sign of coronary atherosclerosis. The aim of this study is to optimize the diagnostic values and radiation exposure in coronary artery calcium-screening examination using multi-slice CT (MSCT) with different image scan protocols. The radiation exposure for all protocols is evaluated by using computed tomography dose index (CTDI) phantom measurements. We chose an optimal scanning protocol and evaluated patient radiation dose in the MSCT coronary artery screenings and preserved its expecting diagnostic accuracy. These changes make the MSCT have more operation flexibility and provide more diagnostic values in current practice.

  3. Multi-slice computed tomography for diagnosis of combined thoracoabdominal injury

    Directory of Open Access Journals (Sweden)

    Liu Jun

    2015-07-01

    Full Text Available Purpose: To investigate the diagnostic value of multi-slice computed tomography (MSCT for combined thoracoabdominal injury. Methods: A retrospective study was conducted to analyze the clinical data and MSCT images of 68 patients who sustained a combined thoracoabdominal injury associated with diaphragm rupture, and 18 patients without diaphragm rupture. All the patients were admitted and treated in the Chongqing Emergency Medical Center (a level I trauma center between July 2005 and February 2014. There were 71 males and 15 females with a mean age of 39.1 years (range 13e88 years. Among the 86 patients, 40 patients suffered a penetrating injury, 46 suffered a blunt injury as a result of road traffic accident in 21 cases, fall from a height in 16, and crushing injury in 9. The MSCT images were retrospectively reviewed by two radiologists. The results of CT diagnosis were compared with surgical findings and/or follow-up results. Results: Among the 86 cases, diaphragm discontinuity was found in 29 cases, segmental nonrecognition of the diaphragm in 14, diaphragmatic hernia in 21, collar sign in 14, dependent viscera sign in 18, elevated abdominal organs in 21, bowel wall thickening and/or hematoma in 6, and pneumoperitoneum in 8. CT diagnostic accuracy for diaphragm rupture was 88.4% in the right side and 90.7% in the left side. CT diagnostic accuracy for hemopneumothorax, pulmonary contusion, mediastinal hemorrhage, kidney and adrenal gland injuries was 100%, while for liver, spleen and pancreas injuries was 96.5%, 96.5%, 94.2% respectively. Conclusion: To reach an early diagnosis of combined thoracoabdominal injury, surgeons and radiologists should be familiar with all kinds of images which might show signs of diaphragm rupture, such as diaphragm discontinuity, segmental nonrecognition of the diaphragm, dangling diaphragm sign, diaphragm herniation, collar sign, dependent viscera sign, and elevated abdominal organs.

  4. CT Imaging: Basics and New Trends

    Science.gov (United States)

    Peyrin, Françoise; Engelke, Klaus

    This chapter presents the principle of X-ray CT and its evolution during the last 40 years. The first section describes the physical basis of X-ray CT, tomographic image reconstruction algorithms, and the source of artifacts in X-ray CT images. The second section is devoted to the evolution of CT technology from the first translation-rotation systems to multi-slice spiral CTs currently used today. The next section addresses specific developments of CT technology and applications, like perfusion CT, quantitative CT, and spectral CT. The fourth section introduces the problem of radiation exposure delivered to the patient and its evaluation. Finally the last section addresses the development in micro- and even nano-CT which is a rapidly evolving area in preclinical imaging and biology.

  5. Evaluation of Blood Flow Patterns of Solitary Pulmonary Nodules with Dynamic Multi-slice Spiral Computed Tomography

    Institute of Scientific and Technical Information of China (English)

    LIShenjiang; XIAOXiangsheng; LIHuimin; LIUShiyuan; LIChengzhou; ZHANGChenshi; TAOZhiwei; YANGChunshan

    2004-01-01

    To evaluate the efficacy of dynamic multi-slice spiral computed tomography (MSCT) for providing quantitative information about blood flow patterns of solitary pulmonary nodules (SPNs) and differentiating solitary pulmonary nodules (SPNs). Methods: 37 patients with SPNs (diameter0.01). SFN-to-aorta ratio in inflammatory SPNs (20.78%±4.14) was significantly higher than that in benign (2.00%±2.26) and malig nant (14.63%±6.22) SPNs (P0.01). Conclusion: MSCT provides quantitative information about blood flow patterns of solitary pulmonary nodules (SPNs) and is applicable diagnostic method for differentiating SPNs.

  6. Anti-aliasing weighting functions for multislice helical CT

    Science.gov (United States)

    La Riviere, Patrick J.; Pan, Xiaochuan

    2002-05-01

    We develop a new projection weighting function for interpolation and reconstruction of multi-slice helical computed tomography data with the hope of reducing longitudinal aliasing in reconstructed volumes. The weighting function is based on the application of the Papoulis generalized sampling theorem to the interlaced longitudinal samples acquired by the multi-slice scanner. We call the approach 180MAA, for multi-slice anti-aliasing. For pitch 3, the 180MAA approach yields high-quality images of the 3D Shepp-Logan phantom as well as a longitudinal MTF superior to that of the 180MLI approach, which is based on the use of linear interpolation. However, it is not as successful at mitigating aliasing as had been doped due to the presence of a significant and unexpected aliasing component that can be attributed to the small cone angle in multi-slice helical CT. The presence of this effect is interesting and significant in its own right, however.

  7. Application of spiral CT image 3D reconstruction in severe talar neck fracture

    Institute of Scientific and Technical Information of China (English)

    HE Fei; HUANG He; DENG Ya-min; Wang Bing; ZHANG Chun-qiang; ZHAO Zhi; TANG Xi-zhang; ZHOU Zhao-wen; ZHAO Xue-ling

    2007-01-01

    Objective:To explore the application of the spiral computerized tomography (CT) image three-dimensional(3D ) reconstruction technique associated with the conventional radiography in the diagnosis and treatment of severe talar neck fracture. Methods:Using the multi-slice spiral CT image 3D reconstruction technique,we analysed 11 cases of talar neck fracture.The fractures were reduced and fixed through a minimal incision and internal fixation with titanium cannulated lag screws. Results:In the 11 cases,the results of CT image 3D reconstruction were in concordance with plain radiograph in 6 case of Hawkins type H.And the remaining 5 cases of Hawkins types Ⅲ and Ⅳ could not be classified exactly only by radiographs,one of whom was misdiagnosed.After using the CT image 3D reconstruction,the 5 cases were classified exactly before osteosynthesis.The classifications of these 11 cases were confirmed finally by surgical findings.The duration of operation were 45-140 min,averaging 81min (including the duration of C-arm fluoroscopy).X-ray exposure time was 6-58 seconds,averaging 22 seconds.The blood loss was less than 100 ml.The fracture union was achieved in 3 months. No nonunion, talus avascular necrosis or joint surface collapse occurred.Postoperative follow-up was from 1 to 25 months.According to Hawkins score,excellent result was found in 6 type Ⅱ cases and 1type Ⅲ case;good result in 1 type Ⅲ case with both medial and lateral malleolar fracture,1 type Ⅲ with medial malleolus fractures and 1 open type Ⅲ;fair result in 1 open type Ⅳ with lateral malleolus fracture. Conclusions:By using the multi-slice spiral CT image 3D reconstruction associated with radiography to diagnose and treat severe talar neck fractures,the accuracy of diagnosis can be improved obviously. Based on this technique,more consummate operational plan can be designed and performed so as to achieve a better therapeutic effect.

  8. Multi-slice computed tomography urography after diuretic injection in children with urinary tract dilatation

    Energy Technology Data Exchange (ETDEWEB)

    Kosucu, P.; Ahmetoglu, A.; Imamoglu, M.; Cay, A.; Ozdemir, O.; Dinc, H.; Kosucu, M.; Sari, A.; Saruhan, H.; Gumele, H.R. [Farabi Hospital, Trabzon (Turkey). Dept. of Radiology

    2004-02-01

    To evaluate the potential use of multi-slice computed tomography urography (MSCTU) after diuretic injection in children with urinary tract dilatation. MSCTU was performed in 19 patients (11 boys, 8 girls, mean age 5.4 years) with suspicion of urinary tract obstruction and dilatation. Furosemide, 1 mg/kg, was injected 3 min before contrast material administration and followed by a bolus of 30 ml of physiologic saline solution immediately after application of contrast material. Excretory-phase images were obtained through the abdomen and pelvis beginning 10 min after initiation of the injection of contrast material. Maximum intensity projection (MIP) and volume rendering (VR) images were post-processed to obtain urographic views. MSCTU revealed pathology in 16 of 19 patients, while 3 patients had normal findings. Ureteropelvic obstruction was found in 4 patients, obstructive megaureter in 8. Both ureteropelvic obstruction and obstructive megaureter were disclosed in 1 patient, partial ureteral duplication in 1 patient, and both complete ureteral duplication and ureterocele in 2 patients. In all patients, MIP and VR images could satisfactorily show the pathologies of the urinary tract. The estimated effective average doses of MSCTU were higher than IVU. Preliminary results of furosemide-enhanced MSCTU demonstrated consistently dilated urinary tracts, obstruction levels, and underlying pathologies better than US and IVU.

  9. [Diagnostic value of multi-slice spiral computerized tomographic fistulography in congenital fistula of neck].

    Science.gov (United States)

    Zheng, H; Ye, Q; Wang, X Y; Zheng, X H; Yang, X Q; Chen, Y; Jiang, Y; Li, R Y

    2017-08-07

    Objective: To investigate the usefulness and effectiveness of multi-slice spiral computerized tomographic fistulography (MSCTF) in the diagnosis and treatment of congenital fistula of neck. Methods: Thirty-four patients with thyroglossal fistulasor branchial cleft fistulas who were initial treated from July 2008 to August 2015 in Fujian Provincial Hospital were retrospectively analyses. Thirteen males and 21 females patients aging from 3 to 46 years old with a median age of 37 were included. There were thyroglossal fistula in 6 cases, the first branchialcleft fistula in 9 cases, the second branchialcleft fistula in 3 cases, the third branchialcleft fistula in 9 cases, and the fourth branchialcleft fistula in 7 cases. All the patients underwent preopeative MSCTF and the diagnoses were finally confirmed with surgery and histopathology. Multiplanar reconstruction(MPR), maximumintensity projection(MIP)and volume rendering(VR) were completed with AW Volume Share 4.2 image processing software after initial CT scanning.The internal openings, distribution, and neighboring relationship of the fistulas showed by MSCTF were analyzed and the surgical strategies were subsequently made. Results: Except 2 cases, 32 patients had obtained successfully MSCTF image. The presence and location of the fistulas could be showed clearly on MSCTF. Based on the results of MSCTF examination, the surgical planes to treat the fistulas were made. The fistulas in all cases were successfully found and excised. Three cases underwent selective neck dissection. Postoperative infection occurred in 1 case. Unilateral vocal fold paralysis due to surgery recovered 3 months after surgery with follow-up. One case lost follow-up, the remaining 33 cases were followed up for 13-97 months with no the fistula recurrence. Conclusions: MSCTF could provide valuable information and benefit surgical planning by demonstrating the coursesof congenital fistulas of neck in detail.

  10. Unsupervised motion-compensation of multi-slice cardiac perfusion MRI

    DEFF Research Database (Denmark)

    Stegmann, M.B.; Ólafsdóttir, H; Larsson, H.B.W.

    2005-01-01

    This paper presents a novel method for registration of single and multi-slice cardiac perfusion MRI. Utilising off-line computer intensive analyses of variance and clustering in an annotated training set, the presented method is capable of providing registration without any manual interaction...

  11. The Diagnosis Value of Perfusion Parameters of Multi-slice Spiral CT on the Liver Blood Flow of Hepatocellular Carcinoma%多层螺旋CT灌注参数对肝癌血流变化的诊断价值

    Institute of Scientific and Technical Information of China (English)

    李金平

    2011-01-01

    肝脏CT灌注成像是一种新兴功能成像技术,通过同层动态扫描获得多种灌注参数,对肝动脉和门静脉血流变化进行定量分析,进而反映肝癌形成过程中的血流动力学改变.目前,CT灌注成像技术在原发性肝癌中的研究较多,但对肝癌灌注参数的分析较零散.因此,笔者对多层螺旋CT灌注成像技术在原发性肝癌血流动力学变化方面的研究作一综述.%CT perfusion imaging of liver is an emerging imaging technology, a variety of perfusion parameters can be obtained through the dynamic scans of same level to make quantitative analysis on the blood flow changes of the hepatic artery and portal vein, further to reflect the hemodynamics in the development of liver cancer. Currently, more CT perfusion imaging studies are on primary hepatic carcinoma, but the analysis of perfusion parameters is fragmented. Therefore, the purpose of this paper is to make a review on the CT perfusion techniques in the studies of hemodynamic changes in primary hepatic carcinoma.

  12. Values of multi-slice spiral computed tomography on predicting hypovolemic shock in patients with severe multiple trauma

    Directory of Open Access Journals (Sweden)

    Yang LI

    2013-01-01

    Full Text Available Objective  To investigate the value of multi-slice spiral computed tomography (MSCT on predicting hypovolemic shock in patients with severe multiple trauma. Methods  The clinical and MSCT data of 63 patients with severe multiple trauma admitted to the Trauma Center from Jan. 2008 to Dec. 2011 were retrospectively reviewed. According to the occurrence of hypovolemic shock in 24 hours after CT scan, the patients were divided into shock group (n=34 and stable group (n=29. Blood pressure, heart rate, shock index and injury severity score (ISS on admission were collected and analyzed. Transverse (T and anteroposterior (AP diameter of inferior vena cava (IVC, diameter of abdominal aorta, CT values of enhanced CT of abdominal organs both in early and late phase were measured. The differences of aforementioned parameters between the two groups were compared by Student's ttest. The values of above indexes showing significant difference between the two groups on predicting hypovolemic shock were analyzed by using receiver operating characteristic (ROC curve and logistic regression analysis. Results  The shock index, ISS and collapsibility index (T/AP of IVC in 4 abdominal levels were significantly greater in shock group than in stable group (P<0.05. In early phase of enhanced CT, the mean CT value of spleen was significantly lower in shock group (93±16HU than in stable group (112±24HU, P<0.01, while the mean CT value of adrenal gland was higher in shock group (153±35HU than in stable group (131±24HU, P<0.01. In delayed phase, the mean CT value of renal medulla was significantly lower in shock group (193±57HU than in stable group (228±53HU, P<0.05. The diagnostic cutoff value of ROC curve of shock index, ISS, collapsibility index (T/AP of IVC, CT value of spleen and adrenal gland in early phase, CT value of renal medulla in delayed phase were 1.19, 19.5, 3.02, 115HU, 150HU and 184HU, respectively. Logistic regression analysis showed that ISS, T

  13. Hepatic focal nodular hyperplasia in children: Imaging features on multi-slice computed tomography

    Institute of Scientific and Technical Information of China (English)

    Qing-Yu Liu; Wei-Dong Zhang; Dong-Ming Lai; Ying Ou-yang; Ming Gao; Xiao-Feng Lin

    2012-01-01

    AIM:To retrospectively analyze the imaging features of hepatic focal nodular hyperplasia (FNH) in children on dynamic contrast-enhanced multi-slice computed tomography (MSCT) and computed tomography angiography (CTA) images.METHODS:From September 1999 to April 2012,a total of 218 cases of hepatic FNH were confirmed by either surgical resection or biopsy in the Sun Yat-sen Memorial Hospital of Sun Yat-sen University and the Cancer center of Sun Yat-sen University,including 12 cases (5.5%) of FNH in children (age ≤ 18 years old).All the 12 pediatric patients underwent MSCT.We retrospectively analyzed the imaging features of FNH lesions,including the number,location,size,margin,density of FNH demonstrated on pre-contrast and contrastenhanced computed tomography (CT) scanning,central scar,fibrous sepia,pseudocapsule,the morphology of the feeding arteries and the presence of draining vessels (portal vein or hepatic vein).RESULTS:All the 12 pediatric cases of FNH had solitary lesion.The maximum diameter of the lesions was 4.0-12.9 cm,with an average diameter of 5.5 ± 2.5 cm.The majority of the FNH lesions (10/12,83.3%) had well-defined margins.Central scar (10/12,83.3%) and fibrous septa (11/12,91.7%) were commonly found in children with FNH.Central scar was either isodense (n =7) or hypodense (n =3) on pre-contrast CT images and showed progressive enhancement in 8 cases in the equilibrium phase.Fibrous septa were linear hypodense areas in the arterial phase and isodense in the portal and equilibrium phases.Pseudocapsule was very rare (1/12,8.3%) in pediatric FNH.With the exception of central scars and fibrous septa within the lesions,all 12 cases of pediatric FNH were homogenously enhanced on the contrast-enhanced CT images,significantly hyperdense in the arterial phase (12/12,100.0%),and isodense in the portal venous phase (7/12,58.3%) and equilibrium phase (11/12,91.7%).Central feeding arteries inside the tumors were observed on CTA images for all

  14. Evaluation on the feasibility of assessment of volume perfusion for the whole lung by multi-slice spiral CT%应用多层螺旋CT对全肺容积灌注评价的可行性研究

    Institute of Scientific and Technical Information of China (English)

    孙海涛; 朱小飞; 张霞; 谢元忠; 柳澄

    2015-01-01

    Objective The aim of this study was to evaluate the feasibility of dynamic volume perfusion CT (VPCT) of the whole lung using a 128-slice CT for the quantitative assessment and visualization of pulmonary perfusion.Methods Imaging was performed in a control group of 17 subjects who had no signs of disturbance of pulmonary function or diffuse lung disease, and 15 patients (5 patients with acute pulmonary embolism and 10 with emphysema) who constituted the abnormal lung group. Dynamic VPCT was performed in all subjects, with calculation of pulmonary blood flow (PBF), pulmonary blood volume (PBV), and mean transit time (MTT) generated from dynamic contrast images with a coverage of 20.7 cm. Regional and volumetric PBF, PBV, and MTT were statistically evaluated and compared made between the normal and abnormal lung groups, not with standing a few lungs in big size beyond the coverage of 20.7 cm.Results Regional PBF, PBV, and MTT demonstrated significant differences in the gravitational and was ogravitational directions in the normal lung group (P20.7 cm的覆盖范围,但是在肺实质正常组和肺实质异常组间动态容积灌注CT的PBF和PBV均存在统计学差异(P<0.05).结论 应用128层螺旋CT定量及可视化定性评价全肺动态容积灌注具有可行性,对于全肺的形态和功能学特征仅用一种检查就能进行全面评价.

  15. 多层螺旋CT灌注成像对肺癌化疗效果的临床评价研究%Study on the Clinical Curative Effect Evaluation of Multi-slice Spiral CT Perfusion Imaging in Lung Cancer Chemo-therapy

    Institute of Scientific and Technical Information of China (English)

    白萍

    2014-01-01

    Objective To discuss the change of perfusion parameters before and after lung cancer chemotherapy, evaluate the value of CT perfusion imaging in lung cancer chemotherapy curative effect evaluation. Methods 30 cases meeted a criterion from January to February 2013, which of chemotherapy effect and CT perfusion parameters were analysed before and after chemo-therapy. Results After two cycles of chemotherapy, there were 2 cases with PR, 10 cases with CR, 13 cases with SD, 5 cases with PD in 30 patients. Before chemotherapy BF value in effective group was higher than the invalid group, and the difference was statistically significant (P0. 05). Compared with before treatment, BF value descended and MTT value elevated in effective group (P0. 05). BF, BV, MTT and PS value had no significant difference in valid group before and after treat-ment(P>0. 05). Conclusion CT perfusion imaging can reflect blood supply of non-small cell lung cancer, high blood flow state before chemotherapy and the rise in the average through time after chemotherapy illustrated that it was sensitive to chemotherapy, good curative effect, remission rate.%目的:探讨肺癌化疗前后灌注参数值的改变,评估CT灌注成像在肺癌化疗疗效评价中的价值。方法2013年1月至2013年12月选取符合标准的患者30例,分析其化疗效果和化疗前后CT灌注成像参数值的变化。结果30例患者完成2个周期化疗后PR 2例、CR 10例、SD 13例和PD 5例。化疗前有效组患者BF值高于无效组,差异有统计学意义(P0.05)。有效组患者化疗后BF值下降、MTT值升高,较治疗前差异均有统计学意义(P0.05)。无效组患者化疗前后BF、BV、MTT和PS值变化不大,差异无统计学意义( P>0.05)。结论 CT灌注成像能够反映非小细胞肺癌的血供情况,化疗前高血流量状态及化疗后平均通过时间升高提示其对化疗反应相对敏感,近期疗效好,缓解率高。

  16. Clinical applications of SPECT-CT

    Energy Technology Data Exchange (ETDEWEB)

    Ahmadzadehfar, Hojjat; Biersack, Hans-Juergen (eds.) [University Hospital Bonn (Germany). Dept. of Nuclear Medicine

    2014-06-01

    Covers the full spectrum of clinical applications of SPECT/CT in diagnosis of benign and malignant diseases. Includes chapters on the use of SPECT/CT for dosimetry and for therapy planning. Completely up to date. Many helpful illustrations. SPECT/CT cameras have considerably improved diagnostic accuracy in recent years. Such cameras allow direct correlation of anatomic and functional information, resulting in better localization and definition of scintigraphic findings. In addition to this anatomic referencing, CT coregistration provides superior quantification of radiotracer uptake based on the attenuation correction capabilities of CT. Useful applications of SPECT/CT have been identified not only in oncology but also in other specialties such as orthopedics and cardiology. This book covers the full spectrum of clinical applications of SPECT/CT in diagnosis and therapy planning of benign and malignant diseases. Opening chapters discuss the technology and physics of SPECT/CT and its use for dosimetry. The role of SPECT/CT in the imaging of a range of pathologic conditions is then addressed in detail. Applications covered include, among others, imaging of the thyroid, bone, and lungs, imaging of neuroendocrine tumors, cardiac scintigraphy, and sentinel node scintigraphy. Individual chapters are also devoted to therapy planning in selective internal radiation therapy of liver tumors and bremsstrahlung SPECT/CT. Readers will find this book to be an essential and up-to-date source of information on this invaluable hybrid imaging technique.

  17. Clinical research about diagnostic value of capsule endoscopy combining with multi-slice spiral CT in obscure gastrointestinal bleeding%胶囊内镜联合多排螺旋CT诊断不明原因消化道出血的临床研究

    Institute of Scientific and Technical Information of China (English)

    丁元军

    2013-01-01

    目的 探讨胶囊内镜(capsule endoscopy CE)联合多排螺旋CT(MSCT)在不明原因消化道出血中的诊断作用和价值.方法 收集不明原因消化道出血患者80例,进行胶囊内镜及多排螺旋CT检查,统计两种检查手段病变的检出率及其部位并进行分析.结果 80例中CE诊断阳性46例,诊断阳性率为57.5%;MSCT诊断阳性33例,诊断阳性率为41.3%,P<0.05;CE和MSCT联合诊断的阳性率为63.8%,与CE相比P>0.05,与MSCT相比P<0.05;CE和MSCT的诊断一致率为71.3%;另有34例在检查后进行了外科手术,检出病变34种;CE和MSCT均有病变漏诊,但MSCT漏诊更多.结论 ①CE联合MSCT检查对不明原因消化道出血的诊断阳性率较CE有所提高,但无统计学意义.②CE联合MSCT检查在判断小肠肿瘤的病变性质及肠外情况的了解中具有优势,建议对不明原因消化道出血进行CE和MSCT的联合检查.

  18. 256层CT上肢血管成像对血液透析患者自体动静脉内瘘功能不全的评价%Multi-slice CT angiography evaluation of autogenous arteriovenous fistula dysfunction in hemodialysis patients

    Institute of Scientific and Technical Information of China (English)

    金文韬; 李斌; 刘洪超; 刘士远; 郝楠馨; 于红

    2013-01-01

    Objective To evaluate the clinical value of CT angiography (CTA) using 256-slicc CT scanner for autogenous arteriovenous fistula dysfunction in hemodialysis patients. Methods A total of 20 hemodialysis patients with autogenous arteriovenous fistula dysfunction underwent CTA of the affected upper limbs. A total of 80-100 ml- of noniodinatcd contrast agent (iopamidol) was injected at a rate of 3-1. 5 mL/s into the antccubital vein of contralatcral limb. A contrast agent concentration tracking technology was utilized. Aortic arch was regarded as the region of interest (ROI) and the threshold was set at 150 HU. Imaging commenced after a delay of 18 s when ROI arrived at the threshold. In two patients, the delay phase scanning was started at 30 s after the first scanning . The images were reconstructed with standard algorithm, with 0. 625 mm slice thickness and 0. 625 mm slice gap, using different postprocessing techniques such as surface reconstruction, multiple planar reconstruction, maximum intensity projection and volume rendering on the EBW workstation. The cross sectional area of the fistula anastomotic stoma was measured using the vessel analysis and measurement function of the EBW workstation, and compared with the supplying artery. Results The blood vessels in affected limb were clearly displayed on CTA. Of 94 vascular segments in 20 hemodialysis patients, 29 were of stenosis, including 15 at arteriovenous anastomotic stoma (51.7%), 8 at venous outflow in forearm (27.5%), 3 at venous outflow in upper arm ( 10. 3 % ) and 3 at subclavian vein ( 10. 3%). Five cases exhibited collateral circulation formation; 10 had draining vein dilatation; 9 had supplying artery variation and 1 had hematoma in the elbow. Conclusion Autogenous arteriovenous fistula can be accurately evaluated by using CT angiography, which is helpful for guiding management clinically of the patients with chronic renal failure fistula dysfunction.%目的 研究256层CT血管成像对于血液透

  19. Correlation of coronary artery stenosis evaluation with left heart structure and function by multi-slice computed tomography.

    Science.gov (United States)

    Song, L N; Cao, A D; Niu, Y J; Liu, N

    2014-08-07

    The aim of this study was to determine the impact of multi-slice computed tomography (MSCT) evaluation of coronary artery stenosis on left heart structure and systolic function. Coronary artery CT angiography was performed in 200 patients diagnosed with coronary heart disease, and then according to the AHA coronary artery 17-segment fractionation method, the Gensini score (GS) was determined for every narrow segment, and one-stop assessment of the correlation between left heart structure and function was performed. After the grouping of GS quartiles from low to high, there were differences between different patients with regard to LVDD, LADD, LVEDV, LVESV, MM, LVEF, and FS, while no difference in SV and CO. GS showed linear negative correlation with LVEF and FS, and linear positive correlation with LVDD, LADD, LVEDV, LVESV, and MM, while no correlation with SV and CO. That is, GS of coronary artery stenosis was negatively correlated with left ventricular systolic function and positively correlated with myocardial mass. The narrower the coronary artery, the worse the cardiac function and the higher the myocardial hypertrophy. Coronary artery stenosis was one of the important causes of the decrease in left ventricular systolic function and cardiac remodeling.

  20. The Study of Relationship between Inferior Phrenic Artery Originated from Abdominal Aorta and Celiac Trunk by Using Multi-Slice Helical CT%起源于腹主动脉的膈下动脉与腹腔干关系的多层螺旋CT研究

    Institute of Scientific and Technical Information of China (English)

    宫凤玲; 于鹏; 张惠英; 李盖; 赵鹤亮; 孙凤涛

    2011-01-01

    Purpose To explore whether there are some rules in the relationship between inferior phrenic artery (IPA) originated from the abdominal aorta and the celiac trunk. Materials and Methods The origin of IPA in 200 patients (174 with abdomen scan and 26 with chest-abdomen scan) who underwent two-phase enhanced CT scan at Philips 256-slice helical CT were respectively observed. The relationship of the orifice position between IPA originated from the abdominal aorta and the celiac trunk was analysed. Results RIPA was shown in 200 cases with total 201 branches. LIPA was shown in 198 cases with total 203 branches. 2 cases of LIPA were not shown. Bilateral IPA originated from a common stem was seen in 48 of 200 cases (24%). RIPA originated from the celiac trunk in 70/201 cases(34.8%) , from the aorta in 82/201 cases(40.8%), from the right renal artery in 37/201cases (18.4%), from the right accessory renal artery in 4/201cases (2.0%) and from the lefi gastric artery in 8/201 cases (4%). LIPA originated from the celiac trunk in 113/203 cases (55.7%), from the aorta in 77/203 cases (37.g%), from the left gastric artery in 11/203 cases(5.4%) and from the spleen artery in 2/203 cases (1.0%). There are some rules in the relationship between the origin of IPA originated from the abdominal aorta (135cases) and the celiac trunk: ① 98.3% of RIPA located in the 9-12 o'clock position relative to the wall of the aorta. LIPA and IPA which originated from a common stem located in the 12-3 o'clock position relative to the wall of aorta ; ② 80.0% of IPA had orifice located 10mm upper or lower of the orifice of the celiac trunk and the remaining located 10mm lower than the orifice of the celiac trunk.③ 63.8% of RIPA had the orifice located under the orifice of the celiac trunk. 43.4% of LIPA and 54.2% of IPA which originated from a common stem located upper than the orifice of the celiac trunk. ④ 86.8% of IPA had the orifice located under the orifice

  1. 肺部鳞癌、腺癌和小细胞性肺癌128层螺旋CT低剂量灌注的差异性研究%Study on the difference of lung squamous cell carcinoma, adenocarcinoma and small cell lung carcinoma with multi-slice spiral CT perfusion of low dose

    Institute of Scientific and Technical Information of China (English)

    张治平; 李振辉; 张大福; 王关顺; 杨光军; 高德培

    2016-01-01

    AIM:To investigate the difference of lung squamous cell carcinoma, adenocarcinoma and small cell lung carcinoma with 128⁃slice spiral CT perfusion of low dose. METHODS:Tumos focus of 81 patients with lung cancer was examined by the 70 kV·50 mAs of 128⁃slice spiral CT perfusion scanning of low dose. The time to peak of the agent (TTP), blood flow (BF), blood volume (BV), permeability (PMB) value of the tumors were estimated according to the model of non⁃deconvolution meth⁃od. The results were analyzed by variance and LSD. RESULTS:The TTP values of squamous cell carcinoma, adenocarcinoma and small cell carcinoma were respectively 15. 62, 17. 91 and 16. 89;the BF ( mL/100 mL/min) values of squamous cell carcinoma, adenocarcinoma and small cell carcinoma were respectively 89.34, 77.27 and 96.49;the BV ( mL/100 mL) values of squamous cell carcinoma, adenocarcinoma and small cell carcinoma were 8.06, 8.94 and 11.95; the PMB (mL/100 mL/min) values of squa⁃mous cell carcinoma, adenocarcinoma, small cell carcinoma of were respectively 13. 79, 15. 17 and 13. 95. TTP values between squamous cell carcinoma and adenocarcinoma were statistically significant ( P0.05) .%目的:探索肺部鳞癌、腺癌和小细胞性肺癌128层螺旋CT低剂量灌注值的差异.方法:对81例肺癌的肿瘤病灶进行70 kV·50 mAs 128层螺旋CT低剂量灌注扫描.根据非去卷积模型法分别获得肿瘤的对比剂达峰时间( TTP )、血流量( BF)、血容量( BV)、毛细血管通透性( PMB)相应灌注图并测量TTP、BF、BV、PMB值.将结果分别进行多组比较和组与组之间两两比较,多组比较采用方差分析,组与组之间比较采用LSD法.结果:81例肺部鳞癌、腺癌和小细胞性癌均获得70 kV·50 mAs 128层螺旋CT低剂量灌注的灌注彩图和灌注值.鳞癌、腺癌、小细胞性癌的 TTP(s)分别是:15.62、17.91、16.89;鳞癌、腺癌、小细胞性癌的 BF(mL/100 m

  2. The Value of Low-concentration Positive Oral Contrast Agent of Multi-slice CT Enterography in Application%口服低浓度阳性对比剂在MSCTE中的应用价值

    Institute of Scientific and Technical Information of China (English)

    沈斌; 朱宗勇; 梁国洪; 吕访贤

    2014-01-01

    目的:评价低浓度阳性对比剂在MSCT小肠造影检查中的应用价值.方法:分段口服自配肠道低浓度碘稀释液2000毫升进行肠道准备,采用多层螺旋CT容积扫描,应用多平面重建(MPR)、曲面重建(CPR)等后处理方式进行轴位、冠状位和矢状位二维图像.结果:34例均无不良反应及并发症,均顺利完成肠道准备和螺旋CT容积采集,肠道里对比剂均可清晰识别肠道,13例小肠充盈较好,21例小肠充盈稍欠佳,回肠充盈效果优于空肠.结论:口服低浓度阳性对比剂MSCTE是小肠疾病实用的检查方法,尤其适合基层医院应用,其临床价值较大.

  3. Clinical application of multi-slice CT angiography in the diagnosis of multiple Takayasu's arteritis%多层螺旋CT血管成像在多发性大动脉炎诊断中的临床价值

    Institute of Scientific and Technical Information of China (English)

    李蓓; 史新平; 陈文华; 邱建国; 邢伟

    2010-01-01

    目的 探讨多层螺旋CT血管成像(MSCTA)在多发性大动脉炎诊断中的临床应用价值.方法 回顾分析18例疑为多发性大动脉炎患者的MSCTA图像,图像后处理方法包括多平面重组、最大密度投影和容积再现技术进行重建.结果 18例按Lupi-Herrea分类法包括Ⅰ型6例,Ⅱ型3例,Ⅲ型9例.管腔情况包括狭窄-阻塞型15例,混合型3例.MSCTA图像可以清楚显示受累血管的异常表现如管壁增厚,管腔狭窄或闭塞,部分伴狭窄后扩张.结论 MSCTA在多发性大动脉炎诊断方面有很高的准确性,可以作为多发性大动脉炎早期诊断的首选影像检查.

  4. Trabecular bone structure parameters from 3D image processing of clinical multi-slice and cone-beam computed tomography data

    Energy Technology Data Exchange (ETDEWEB)

    Klintstroem, Eva; Smedby, Oerjan [Linkoeping University, Center for Medical Image Science and Visualization (CMIV), Linkoeping (Sweden); UHL County Council of Oestergoetland, Department of Radiology, Linkoeping (Sweden); Linkoeping University, Department of Medical and Health Sciences (IMH)/Radiology, Linkoeping (Sweden); Moreno, Rodrigo [Linkoeping University, Center for Medical Image Science and Visualization (CMIV), Linkoeping (Sweden); Linkoeping University, Department of Medical and Health Sciences (IMH)/Radiology, Linkoeping (Sweden); Brismar, Torkel B. [KUS Huddinge, Department of Clinical Science, Intervention and Technology at Karolinska Institutet and Department of Radiology, Stockholm (Sweden)

    2014-02-15

    Bone strength depends on both mineral content and bone structure. The aim of this in vitro study was to develop a method of quantitatively assessing trabecular bone structure by applying three-dimensional image processing to data acquired with multi-slice and cone-beam computed tomography using micro-computed tomography as a reference. Fifteen bone samples from the radius were examined. After segmentation, quantitative measures of bone volume, trabecular thickness, trabecular separation, trabecular number, trabecular nodes, and trabecular termini were obtained. The clinical machines overestimated bone volume and trabecular thickness and underestimated trabecular nodes and number, but cone-beam CT to a lesser extent. Parameters obtained from cone beam CT were strongly correlated with μCT, with correlation coefficients between 0.93 and 0.98 for all parameters except trabecular termini. The high correlation between cone-beam CT and micro-CT suggest the possibility of quantifying and monitoring changes of trabecular bone microarchitecture in vivo using cone beam CT. (orig.)

  5. Experience with volumetric (320 rows) pediatric CT

    Energy Technology Data Exchange (ETDEWEB)

    Sorantin, E., E-mail: erich.sorantin@medunigraz.at [Division of Pediatric Radiology, Department of Radiology, Medical University Graz (Austria); Riccabona, M. [Division of Pediatric Radiology, Department of Radiology, Medical University Graz (Austria); Stücklschweiger, G.; Guss, H. [Competence Centre for Medical Physics and Radiation Protection, Univ.-Hospital Graz (Austria); Fotter, R. [Division of Pediatric Radiology, Department of Radiology, Medical University Graz (Austria)

    2013-07-15

    The introduction of helical computer tomography (CT) and further progress to multi-slice CT enabled new applications. Most recent developments like the 320-row detector facilitate volume CT, which avoids the over-beaming effect of helical scanning. The 320-row multi-slice detector CT (MDCT) is based on a 16 cm detector; a special acquisition mode allows reconstructing 640 slices from these 16 cm. The shortest tube rotation time is in cardiac mode 0.35 s, otherwise 0.4 s and 0.5 s used. At 0.5 s the machine already reaches the maximum numbers of sub-second projections. Scan modes can be volume, helical and single slice mode. For image acquisition all dose savings technologies like variable tube position for scano-view, active collimation, automated exposure control, bolus and ECG tracking are available. Additionally special acquisition and post-processing techniques like head and body perfusion CT are ready for use on the console. For image reconstruction properties like filtered back projection as well as the latest development of iterative algorithms, an appropriate number of kernels and multi-planar reconstruction in all directions from the volume data at every increment are available. Volume CT allows sub second scanning of 16 cm z-coverage which, however, makes administration of intravenous contrast medium to “hit or miss” event. The aim of this paper is to present the application of volume CT to body scanning in children. Representative examples of neck, cardiac and skeletal investigations are given.

  6. 直接采用二维多截面时步法有限元的斜槽异步电机模型%Direct Modeling of Induction Motors with Skewed Rotor Slots Using 2-D Multi-Slice Model and Time Stepping FEM

    Institute of Scientific and Technical Information of China (English)

    傅为农; 江建中

    2000-01-01

    The geometrical feature of the skewed rotor slots in induction motors makes the 2-dimensional (2-D) finite element method (FEM) not directly applicable. Based on the multi-slice model in this paper, a time stepping 2-D eddy-current FEM is described to study the steady-state operation and the starting process of induction machines with skewed rotor slots. The fields of the multi-slices are solved in parallel, and thus the effects of skewed slots and eddy-current can be taken into account directly. The basic formulas for the multi-slice model are derived. Special technique to reduce computation time in solving the coupled system equations is also described. The results obtained by using the program developed have very good correlation with the test data.

  7. A simultaneous multi-slice selective J-resolved experiment for fully resolved scalar coupling information

    Science.gov (United States)

    Zeng, Qing; Lin, Liangjie; Chen, Jinyong; Lin, Yanqin; Barker, Peter B.; Chen, Zhong

    2017-09-01

    Proton-proton scalar coupling plays an important role in molecular structure elucidation. Many methods have been proposed for revealing scalar coupling networks involving chosen protons. However, determining all JHH values within a fully coupled network remains as a tedious process. Here, we propose a method termed as simultaneous multi-slice selective J-resolved spectroscopy (SMS-SEJRES) for simultaneously measuring JHH values out of all coupling networks in a sample within one experiment. In this work, gradient-encoded selective refocusing, PSYCHE decoupling and echo planar spectroscopic imaging (EPSI) detection module are adopted, resulting in different selective J-edited spectra extracted from different spatial positions. The proposed pulse sequence can facilitate the analysis of molecular structures. Therefore, it will interest scientists who would like to efficiently address the structural analysis of molecules.

  8. Assessment of left atrial volume and function: a comparative study between echocardiography, magnetic resonance imaging and multi slice computed tomography

    DEFF Research Database (Denmark)

    Kühl, J Tobias; Lønborg, Jacob; Fuchs, Andreas

    2012-01-01

    dynamic LA volume changes. Conversely, cardiac magnetic resonance imaging (CMR) and multi-slice computed tomography (MSCT) appears more appropriate for such measures. We sought to determine the relationship between LA size assessed with TTE and LA size and function assessed with CMR and MSCT. Fifty...

  9. Virtual colonoscopy with multi-slice computed tomography; Virtuelle Koloskopie mit der Mehrschichtcomputertomographie. Vorlaeufige Ergebnisse

    Energy Technology Data Exchange (ETDEWEB)

    Rust, G.-F.; Eisele, O.; Reiser, M. [Institut fuer Klinische Radiologie, Klinikum Grosshadern, Muenchen Univ. (Germany); Hoffmann, J.N.; Kopp, R.; Fuerst, H. [Chirurgische Klinik und Poliklinik, Klinikum der Univ. Muenchen (Germany)

    2000-03-01

    Subject: Using multi-slice computed tomography (MSCT) large body areas can scanned with high spatial resolution. In this study, MSCT was employed for virtual colonoscopy in various pathologies of the colon. Results: Nine polyps and four of five colon carcinomas were detected using MSCT virtual colonoscopy. In three patients with ulcerative colitis virtual coloscopy revealed morphological alterations compatible with this disease. In two of four patients with multiple diverticula of the colon the true extent of the disorder could be assessed in virtual colonoscopy. (orig.) [German] Fragestellung: Die Mehrschichtcomputertomographie (MSCT) vermag, grosse Organbereiche mit hoher raeumlicher Aufloesung zu untersuchen. Daher koennen auch fuer die virtuelle Koloskopie eine bisher nicht erreichbare Ortsaufloesung und Detailtreue erwartet werden. Die ersten Ergebnisse mit der MSCT-Koloskopie bei unterschiedlichen pathologischen Veraenderungen des Kolons werden vorgestellt. Ergebnisse: 4 von 5 Kolonkarzinomen konnten mit der virtuellen Koloskopie dargestellt werden. Bei 3 Patienten wurden mit der virtuellen Koloskopie typische Veraenderungen der Colitis ulcerosa dargestellt, wovon ein Patient die konventionelle Koloskopie nicht tolerierte. Bei 9 Patienten mit Kolonpolypen stimmten die virtuelle und konventionelle Koloksopie vollstaendig ueberein. Bei 4 Patienten mit Divertikulose war mit der virtuellen Koloskopie nur in 2 Faellen der Befund vollstaendig zu sichern. (orig.)

  10. Multi-slicing strategy for the three-dimensional discontinuity layout optimization (3D DLO).

    Science.gov (United States)

    Zhang, Yiming

    2017-03-01

    Discontinuity layout optimization (DLO) is a recently presented topology optimization method for determining the critical layout of discontinuities and the associated upper bound limit load for plane two-dimensional and three-dimensional (3D) problems. The modelling process (pre-processing) for DLO includes defining the discontinuities inside a specified domain and building the target function and the global constraint matrix for the optimization solver, which has great influence on the the efficiency of the computation processes and the reliability of the final results. This paper focuses on efficient and reliable pre-processing of the discontinuities within the 3D DLO and presents a multi-slicing strategy, which naturally avoids the overlapping and crossing of different discontinuities. Furthermore, the formulation of the 3D discontinuity considering a shape of an arbitrary convex polygon is introduced, permitting the efficient assembly of the global constraint matrix. The proposed method eliminates unnecessary discontinuities in 3D DLO, making it possible to apply 3D DLO for solving large-scale engineering problems such as those involving landslides. Numerical examples including a footing test, a 3D landslide and a punch indentation are considered, illustrating the effectiveness of the presented method. © 2016 The Authors. International Journal for Numerical and Analytical Methods in Geomechanics published by John Wiley & Sons Ltd.

  11. Whole left ventricular functional assessment from two minutes free breathing multi-slice CINE acquisition

    Science.gov (United States)

    Usman, M.; Atkinson, D.; Heathfield, E.; Greil, G.; Schaeffter, T.; Prieto, C.

    2015-04-01

    Two major challenges in cardiovascular MRI are long scan times due to slow MR acquisition and motion artefacts due to respiratory motion. Recently, a Motion Corrected-Compressed Sensing (MC-CS) technique has been proposed for free breathing 2D dynamic cardiac MRI that addresses these challenges by simultaneously accelerating MR acquisition and correcting for any arbitrary motion in a compressed sensing reconstruction. In this work, the MC-CS framework is combined with parallel imaging for further acceleration, and is termed Motion Corrected Sparse SENSE (MC-SS). Validation of the MC-SS framework is demonstrated in eight volunteers and three patients for left ventricular functional assessment and results are compared with the breath-hold acquisitions as reference. A non-significant difference (P > 0.05) was observed in the volumetric functional measurements (end diastolic volume, end systolic volume, ejection fraction) and myocardial border sharpness values obtained with the proposed and gold standard methods. The proposed method achieves whole heart multi-slice coverage in 2 min under free breathing acquisition eliminating the time needed between breath-holds for instructions and recovery. This results in two-fold speed up of the total acquisition time in comparison to the breath-hold acquisition.

  12. CT perfusion: principles, applications, and problems

    Science.gov (United States)

    Lee, Ting-Yim

    2004-10-01

    The fast scanning speed of current slip-ring CT scanners has enabled the development of perfusion imaging techniques with intravenous injection of contrast medium. In a typical CT perfusion study, contrast medium is injected and rapid scanning at a frequency of 1-2 Hz is used to monitor the first circulation of the injected contrast medium through a 1-2 cm thick slab of tissue. From the acquired time-series of CT images, arteries can be identified within the tissue slab to derive the arterial contrast concentration curve, Ca(t) while each individual voxel produces a tissue residue curve, Q(t) for the corresponding tissue region. Deconvolution between the measured Ca(t) and Q(t) leads to the determination of cerebral blood flow (CBF), cerebral blood volume (CBV) and mean transit time (MTT) in brain studies. In this presentation, an important application of CT perfusion in acute stroke studies - the identification of the ischemic penumbra via the CBF/CBV mismatch and factors affecting the quantitative accuracy of deconvolution, including partial volume averaging, arterial delay and dispersion are discussed.

  13. Is correction necessary when clinically determining quantitative cerebral perfusion parameters from multi-slice dynamic susceptibility contrast MR studies?

    Science.gov (United States)

    Salluzzi, M.; Frayne, R.; Smith, M. R.

    2006-01-01

    Several groups have modified the standard singular value decomposition (SVD) algorithm to produce delay-insensitive cerebral blood flow (CBF) estimates from dynamic susceptibility contrast (DSC) perfusion studies. However, new dependences of CBF estimates on bolus arrival times and slice position in multi-slice studies have been recently recognized. These conflicting findings can be reconciled by accounting for several experimental and algorithmic factors. Using simulation and clinical studies, the non-simultaneous measurement of arterial and tissue concentration curves (relative slice position) in a multi-slice study is shown to affect time-related perfusion parameters, e.g. arterial-tissue-delay measurements. However, the current clinical impact of relative slice position on amplitude-related perfusion parameters, e.g. CBF, can be expected to be small unless any of the following conditions are present individually or in combination: (a) high concentration curve signal-to-noise ratios, (b) small tissue mean transit times, (c) narrow arterial input functions or (d) low temporal resolution of the DSC image sequence. Recent improvements in magnetic resonance (MR) technology can easily be expected to lead to scenarios where these effects become increasingly important sources of inaccuracy for all perfusion parameter estimates. We show that using Fourier interpolated (high temporal resolution) residue functions reduces the systematic error of the perfusion parameters obtained from multi-slice studies. Preliminary results associated with this paper were presented at ISMRM 12th Scientific Meeting and Exhibition, Kyoto, Japan, 2004.

  14. Is correction necessary when clinically determining quantitative cerebral perfusion parameters from multi-slice dynamic susceptibility contrast MR studies?

    Science.gov (United States)

    Salluzzi, M; Frayne, R; Smith, M R

    2006-01-21

    Several groups have modified the standard singular value decomposition (SVD) algorithm to produce delay-insensitive cerebral blood flow (CBF) estimates from dynamic susceptibility contrast (DSC) perfusion studies. However, new dependences of CBF estimates on bolus arrival times and slice position in multi-slice studies have been recently recognized. These conflicting findings can be reconciled by accounting for several experimental and algorithmic factors. Using simulation and clinical studies, the non-simultaneous measurement of arterial and tissue concentration curves (relative slice position) in a multi-slice study is shown to affect time-related perfusion parameters, e.g. arterial-tissue-delay measurements. However, the current clinical impact of relative slice position on amplitude-related perfusion parameters, e.g. CBF, can be expected to be small unless any of the following conditions are present individually or in combination: (a) high concentration curve signal-to-noise ratios, (b) small tissue mean transit times, (c) narrow arterial input functions or (d) low temporal resolution of the DSC image sequence. Recent improvements in magnetic resonance (MR) technology can easily be expected to lead to scenarios where these effects become increasingly important sources of inaccuracy for all perfusion parameter estimates. We show that using Fourier interpolated (high temporal resolution) residue functions reduces the systematic error of the perfusion parameters obtained from multi-slice studies.

  15. Evaluation of MRI-based Polymer Gel Dosimetry for Measurement of CT Dose Index (CTDI on 64 slices CT Scanners

    Directory of Open Access Journals (Sweden)

    Leaila Karimi-Afshar

    2009-06-01

    Full Text Available Introduction: Computed tomography (CT has numerous applications in clinical procedures but its main problem is its high radiation dose to the patients compared to other imaging modalities using x-ray. CT delivers approximately high doses to the nearby tissues due to the scattering effect, fan beam (beam divergence and limited collimator efficiency. The radiation dose from multi-slice scanners is greater than the single-slice scanners and since multi-slice scanners increasingly employ a wide beam, 100 mm ion chambers currently used in measuring the CTDI100, are not capable of accurately measuring the total dose profile of the slice width. Therefore, the CT dose is underestimated by using them. The purpose of this study is to measure the Computed Tomography Dose Index (CTDI of a GE multi-slice CT scanner (64-slice using polymer gel dosimetry based on MRI imaging (MRPD. CTDI is the sum of point doses along the central axis and estimates the average patient dose during CT scanning. Materials and Methods: For measuring CTDI, after designing and fabricating the phantom and preparing the MAGIC gel, MRI imaging using a 1.5 T Siemens MRI scanner was performed with the imaging parameters of ST = 2 mm, NEX = 1, TE = 20-640 ms and TR = 2000 ms. CTDI was measured with a 100 mm ion chamber (CTDI100 and also the MAGIC gel with MRPD method for 10 mm and 40 mm CT scan nominal widths. Results: Following the measurement of the CTDI100 for 10 mm and 40 mm nominal slice widths of the multi-slice scanner using both ion chamber and MAGIC gel, the results showed that the ion chamber underestimates CTDI100 by 28.71% and 14.03% compared to gel for 10 mm and 40 mm respectively. Discussion and Conclusion: It was concluded from this study that gel dosimeters have the capability to measure CTDI in wide beams of multi-slice CT scanners whereas 100 mm standard ion chamber due to its limited length is not reliable even for a 10 mm beam width. In addition, due to the 3

  16. Comparison of Cone Beam Computed Tomography and Multi Slice Computed Tomography Image Quality of Human Dried Mandible using 10 Anatomical Landmarks

    Science.gov (United States)

    Saati, Samira; Kaveh, Fatemeh

    2017-01-01

    Introduction Cone Beam Computed Tomography (CBCT) has gained a broad acceptance in dentomaxillofacial imaging. Computed Tomography (CT) is another imaging modality for diagnosis and preoperative assessments of the head and neck region. Aim Considering the increased radiation exposure and high cost of CT, this study sought to subjectively assess the image quality of CBCT and Multi Slice CT (MSCT). Materials and Methods A dry human mandible was scanned by five CBCT systems (New Tom 3G, Scanora, CRANEX 3D, Promax and Galileos) and one MSCT system. Three independent oral and maxillofacial radiologists reviewed the CBCT and MSCT scans for the quality of 10 landmarks namely mental foramen, trabecular bone, Periodontal Ligament (PDL), dentin, incisive canal, mandibular canal, dental pulp, enamel, lamina dura and cortical bone using a five-point scale. Results Significant differences were found between MSCT and CBCT and among the five CBCT systems (p<0.05) in visualization of different anatomical structures. A fine structure such as the incisive canal was significantly less visible and more variable among the systems in comparison with other anatomical landmarks such as the mental foramen, mandibular canal, cortical bone, dental pulp, enamel and dentin (p<0.05). The Cranex 3D and Promax systems were superior to MSCT and all other CBCT systems in visualizing anatomical structures. Conclusion The CBCT image quality was superior to that of MSCT even though some variability existed among different CBCT systems in visualizing fine structures. Considering the low radiation dose and high resolution, CBCT may be beneficial for dentomaxillofacial imaging. PMID:28384972

  17. 多层螺旋CT肠道造影在溃疡性结肠炎活动期的影像分析%The analysis for images of multi-slice spiral CTE performance levels in active ulcerative ;colitis

    Institute of Scientific and Technical Information of China (English)

    赵宾; 王继红

    2016-01-01

    Objective: To investigate the imaging characteristics of the intestinal multi-slice spiral CT enterography (CTE) in active ulcerative colitis(UC), analyze and summarize its application value. Methods: A total 43 cases diagnosed with active UC from April 2014 to April 2015 in our hospital were selected and divided into mild, moderate and severe three levels with each level as a group, treated by multi-slice spiral CTE examination system based on the improved Mayo system, comparing different performances of CTE levels. Results:43 cases of UC patients participating in the study, eight patients were mild, 16 cases were moderate and 19 cases were severe. There was statistically different in the intestinal mucosa in the presence of air bubbles between the mild and moderate group (x2=21.62; P0.05). Conclusion:UC patients CTE examination, which can effectively conduct a comprehensive assessment against bowel, intestinal and parenteral, provide favorable conditions for the activity of UC clinical diagnosis and classification.%目的:观察多层螺旋CT肠道造影(CTE)在溃疡性结肠炎活动期(UC)中的成像特点,分析探讨其应用价值。方法:选取43例确诊的活动期UC患者,对其行多层螺旋CTE检查,依据改良后的Mayo系统将患者分为轻、中、重三个等级,每个等级为一组,对比不同等级患者CTE的表现。结果:43例UC患者中,8例为轻度,16例为中度,19例为重度,将三组患者多层螺旋CTE检查结果进行对比,其中轻度组与中度组对比,于肠黏膜下气泡一项上差异存在统计学意义(x2=21.62,P<0.05);中度组与重度组进行对比,于结肠袋消失情况、淋巴结肿大情况以及肠壁分层情况3个项目上差异有统计学意义(x2=25.95,x2=17.46,x2=19.46;P<0.05);而于肠黏膜强化程度增加、肠壁增厚、直肠周围脂肪沉积以及肠腔狭窄等项目上,差异均无统计学意义(F=0.36,F=1.58,F=0.31,P>0.05)

  18. Multi-detector CT in the paediatric urinary tract

    Energy Technology Data Exchange (ETDEWEB)

    Damasio, M.B., E-mail: mariabdamasio@ospedale-gaslini.ge.it [Paediatric Radiology, Giannina Gaslini Institute, Genoa (Italy); Darge, K. [Department of Radiology, Children' s Hospital of Philadelphia, Philadelphia (United States); Riccabona, M. [Department of Radiology, Division of Paediatric Radiology, University Hospital Graz (Austria)

    2013-07-15

    The use of paediatric multi-slice CT (MSCT) is rapidly increasing worldwide. As technology advances its application in paediatric care is constantly expanding with an increasing need for radiation dose control and appropriate utilization. Recommendations on how and when to use CT for assessment of the paediatric urinary tract appear to be an important issue. Therefore the European Society of Paediatric Radiology (ESPR) uroradiology task force and European Society of Urogenital Radiology (ESUR) paediatric working groups created a proposal for performing renal CT in children that has recently been published. The objective of this paper is to discuss paediatric urinary tract CT (uro-CT) in more detail and depth. The specific aim is not only to offer general recommendations on clinical indications and optimization processes of paediatric CT examination, but also to address various childhood characteristics and phenomena that facilitate understanding the different approach and use of uro-CT in children compared to adults. According to ALARA principles, paediatric uro-CT should only be considered for selected indications provided high-level comprehensive US is not conclusive and alternative non-ionizing techniques such as MR are not available or appropriate. Optimization of paediatric uro-CT protocols (considering lower age-adapted kV and mAs) is mandatory, and the number of phases and acquisition series should be kept as few as possible.

  19. Modern CT applications in veterinary medicine.

    Science.gov (United States)

    Garland, Melissa R; Lawler, Leo P; Whitaker, Brent R; Walker, Ian D F; Corl, Frank M; Fishman, Elliot K

    2002-01-01

    Although computed tomography (CT) is used primarily for diagnosis in humans, it can also be used to diagnose disease in veterinary patients. CT and associated three-dimensional reconstruction have a role in diagnosis of a range of illnesses in a variety of animals. In a sea turtle with failure to thrive, CT showed a nodal mass in the chest, granulomas in the lungs, and a ball in the stomach. CT of a sea dragon with balance and movement problems showed absence of the swim bladder. In a sloth with failure to thrive, CT allowed diagnosis of a coin in the intestine. CT of a puffin with failure to thrive showed a mass in the chest, which was found to be a hematoma. In a smooth-sided toad whose head was tilted to one side and who was circling in that direction, CT showed partial destruction of the temporal bone. CT of a domestic cat with listlessness showed a mass with focal calcification, which proved to be a leiomyosarcoma. CT of a sea otter showed pectus excavatum, which is caused by the animal smashing oysters against its chest. In a Japanese koi with abdominal swelling, CT allowed diagnosis of a hepatoma.

  20. Hemodynamic study of hepatocellular car-cinoma nodules by multi-slice spiral computed tomographic perfusion

    Institute of Scientific and Technical Information of China (English)

    马国林

    2013-01-01

    Objective To analyze the 64-slice computed tomographic(CT) perfusion parameters of hepatocellular carcinoma(HCC) nodule so as to assess the diagnostic value of hemodynamic changes of HCC nodule by this perfusion

  1. Description of patellar movement by 3D parameters obtained from dynamic CT acquisition

    Science.gov (United States)

    de Sá Rebelo, Marina; Moreno, Ramon Alfredo; Gobbi, Riccardo Gomes; Camanho, Gilberto Luis; de Ávila, Luiz Francisco Rodrigues; Demange, Marco Kawamura; Pecora, Jose Ricardo; Gutierrez, Marco Antonio

    2014-03-01

    The patellofemoral joint is critical in the biomechanics of the knee. The patellofemoral instability is one condition that generates pain, functional impairment and often requires surgery as part of orthopedic treatment. The analysis of the patellofemoral dynamics has been performed by several medical image modalities. The clinical parameters assessed are mainly based on 2D measurements, such as the patellar tilt angle and the lateral shift among others. Besides, the acquisition protocols are mostly performed with the leg laid static at fixed angles. The use of helical multi slice CT scanner can allow the capture and display of the joint's movement performed actively by the patient. However, the orthopedic applications of this scanner have not yet been standardized or widespread. In this work we present a method to evaluate the biomechanics of the patellofemoral joint during active contraction using multi slice CT images. This approach can greatly improve the analysis of patellar instability by displaying the physiology during muscle contraction. The movement was evaluated by computing its 3D displacements and rotations from different knee angles. The first processing step registered the images in both angles based on the femuŕs position. The transformation matrix of the patella from the images was then calculated, which provided the rotations and translations performed by the patella from its position in the first image to its position in the second image. Analysis of these parameters for all frames provided real 3D information about the patellar displacement.

  2. A multicenter, randomized controlled trial of immediate total-body CT scanning in trauma patients (REACT-2).

    NARCIS (Netherlands)

    Sierink, J.C.; Saltzherr, T.P.; Beenen, L.F.; Luitse, J.S.; Hollmann, M.W.; Reitsma, J.B.; Edwards, M.J.R.; Hohmann, J.; Beuker, B.J.; Patka, P.; Suliburk, J.W.; Dijkgraaf, M.G.; Goslings, J.C.

    2012-01-01

    BACKGROUND: Computed tomography (CT) scanning has become essential in the early diagnostic phase of trauma care because of its high diagnostic accuracy. The introduction of multi-slice CT scanners and infrastructural improvements made total-body CT scanning technically feasible and its usage is curr

  3. A multicenter, randomized controlled trial of immediate total-body CT scanning in trauma patients (REACT-2)

    NARCIS (Netherlands)

    J.C. Sierink (Joanne); T.P. Saltzherr (Teun); L.F.M. Beenen (Ludo); J.S.K. Luitse; M.W. Hollmann (Markus); J.B. Reitsma (Johannes); M.J.R. Edwards (Michael); J. Hohmann (Joachim); B.J.A. Beuker (Benn); P. Patka (Peter); J.W. Suliburk (James); M.G.W. Dijkgraaf (Marcel); J.C. Goslings (Carel)

    2012-01-01

    textabstractBackground: Computed tomography (CT) scanning has become essential in the early diagnostic phase of trauma care because of its high diagnostic accuracy. The introduction of multi-slice CT scanners and infrastructural improvements made total-body CT scanning technically feasible and its u

  4. Assessment of left atrial volume and mechanical function in ischemic heart disease: a multi slice computed tomography study

    DEFF Research Database (Denmark)

    Kühl, Jørgen Tobias; Kofoed, Klaus F; Møller, Jacob E

    2010-01-01

    and mechanical function with Multi Slice Computed Tomography (MSCT) in patients with ischemic heart disease. Furthermore, the LA and left ventricular (LV) function was evaluated in relation to signs of clinical heart failure. METHODS AND RESULTS: MSCT was performed in 40 patients with sinus rhythm and ischemic......Left atrial (LA) maximal volume contains prognostic information in patients with heart failure and acute myocardial infarction. However, only few studies have investigated the detailed mechanical function of the LA in these patients. We assessed the feasibility of evaluating LA volume...... heart disease. We enrolled 20 patients with reduced LV ejection fraction (LVEF=45%) and 20 with preserved LVEF (>45%). LA volumes, reservoir, channel and pump function were measured. Interobserver variation for LA volume measures was 1.5% (SD: 6.6%). In patients with reduced LVEF, LA volumes were larger...

  5. Four-Dimensional Computerized Tomography (4D-CT) Reconstruction Based on the Similarity Measure of Spatial Adjacent Images

    Institute of Scientific and Technical Information of China (English)

    ZHANG Shu-xu; ZHOU Ling-hong; CHEN Guang-jie; LIN Sheng-qu; YE Yu-sheng; ZHANG Hai-nan

    2008-01-01

    Objective:To investigate the feasibility of a 4D-CT reconstruction method based on the similarity principle of spatial adjacent images and mutual information measure. Methods:A motor driven sinusoidal motion platform made in house was used to create one-dimensional periodical motion that was along the longitudinal axis of the CT couch. The amplitude of sinusoidal motion was set to an amplitude of ±1 cm. The period of the motion was adjustable and set to 3.5 s. Phantom objects of two eggs were placed in a Styrofoam block, which in turn were placed on the motion platform. These objects were used to simulate volumes of interest undergoing ideal periodic motion. CT data of static phantom were acquired using a multi-slice general electric (GE) LightSpeed 16-slice CT scanner in an axial mode. And the CT data of periodical motion phantom were acquired in an axial and cine-mode scan. A software program was developed by using VC++ and VTK software tools to resort the CT data and reconstruct the 4D-CT. Then all of the CT data with same phase were sorted by the program into the same series based on the similarity principle of spatial adjacent images and mutual information measure among them, and 3D reconstruction of different phase CT data were completed by using the software. Results:All of the CT data were sorted accurately into different series based on the similarity principle of spatial adjacent images and mutual information measures among them. Compared with the unsorted CT data, the motion artifacts in the 3D reconstruction of sorted CT data were reduced significantly, and all of the sorted CT series result in a 4D-CT that reflected the characteristic of the periodical motion phantom. Conclusion:Time-resolved 4D-CT reconstruction can be implemented with any general multi-slice CT scanners based on the similarity principle of spatial adjacent images and mutual information measure.The process of the 4D-CT data acquisition and reconstruction were not restricted to the

  6. Multilayer spiral CT Scanning in Transitional cell Carcinoma of Bladder and Application Analysis%多层螺旋CT扫描在膀胱移行细胞癌中的应用分析

    Institute of Scientific and Technical Information of China (English)

    黄云开; 曾怡群

    2013-01-01

      目的探讨多层螺旋CT诊断膀胱移行细胞癌的应用价值。方法收集48例经手术病理证实的膀胱移行细胞癌患者的CT影像资料与临床资料,展开回顾性的研究。结果48例患者中,CT术前检测出45例,未检出3例;单发病灶25例,多发病灶20例;菜花状28例,乳头状8例,局限性膀胱壁增厚9例。结论多层螺旋CT能够准确地诊断出膀胱移行细胞癌,在病理诊断的基础上,充分结合CT影像资料,将极大提高分期诊断的准确率。%Objective Application of multislice helical CT in diagnosis of bladder transitional cel cancer value. Methods Col ection of 48cases confirmed by operation and pathology of bladder transitional cel cancer patients CT images and clinical data, launched a retrospective study. Results In 48 patients, CT preoperative detection of out of 45 cases, 3 cases of solitary lesions not detected; in 25 cases, multiple lesions in 20 cases; 28 cases of papil ary cauliflower-like, in 8 cases, limitations of the bladder wal thickening in 9 cases. Conclusion Multi slice spiral CT can accurately diagnose of bladder transitional cel carcinoma, the diagnosis based on pathology, ful y integrated CT imaging data, wil greatly improve staging accuracy rate of diagnosis.

  7. CT perfusion of the liver: principles and applications in oncology.

    Science.gov (United States)

    Kim, Se Hyung; Kamaya, Aya; Willmann, Jürgen K

    2014-08-01

    With the introduction of molecularly targeted chemotherapeutics, there is an increasing need for defining new response criteria for therapeutic success because use of morphologic imaging alone may not fully assess tumor response. Computed tomographic (CT) perfusion imaging of the liver provides functional information about the microcirculation of normal parenchyma and focal liver lesions and is a promising technique for assessing the efficacy of various anticancer treatments. CT perfusion also shows promising results for diagnosing primary or metastatic tumors, for predicting early response to anticancer treatments, and for monitoring tumor recurrence after therapy. Many of the limitations of early CT perfusion studies performed in the liver, such as limited coverage, motion artifacts, and high radiation dose of CT, are being addressed by recent technical advances. These include a wide area detector with or without volumetric spiral or shuttle modes, motion correction algorithms, and new CT reconstruction technologies such as iterative algorithms. Although several issues related to perfusion imaging-such as paucity of large multicenter trials, limited accessibility of perfusion software, and lack of standardization in methods-remain unsolved, CT perfusion has now reached technical maturity, allowing for its use in assessing tumor vascularity in larger-scale prospective clinical trials. In this review, basic principles, current acquisition protocols, and pharmacokinetic models used for CT perfusion imaging of the liver are described. Various oncologic applications of CT perfusion of the liver are discussed and current challenges, as well as possible solutions, for CT perfusion are presented.

  8. Development of modern human subadult age and sex estimation standards using multi-slice computed tomography images from medical examiner's offices

    Science.gov (United States)

    Stock, Michala K.; Stull, Kyra E.; Garvin, Heather M.; Klales, Alexandra R.

    2016-10-01

    Forensic anthropologists are routinely asked to estimate a biological profile (i.e., age, sex, ancestry and stature) from a set of unidentified remains. In contrast to the abundance of collections and techniques associated with adult skeletons, there is a paucity of modern, documented subadult skeletal material, which limits the creation and validation of appropriate forensic standards. Many are forced to use antiquated methods derived from small sample sizes, which given documented secular changes in the growth and development of children, are not appropriate for application in the medico-legal setting. Therefore, the aim of this project is to use multi-slice computed tomography (MSCT) data from a large, diverse sample of modern subadults to develop new methods to estimate subadult age and sex for practical forensic applications. The research sample will consist of over 1,500 full-body MSCT scans of modern subadult individuals (aged birth to 20 years) obtained from two U.S. medical examiner's offices. Statistical analysis of epiphyseal union scores, long bone osteometrics, and os coxae landmark data will be used to develop modern subadult age and sex estimation standards. This project will result in a database of information gathered from the MSCT scans, as well as the creation of modern, statistically rigorous standards for skeletal age and sex estimation in subadults. Furthermore, the research and methods developed in this project will be applicable to dry bone specimens, MSCT scans, and radiographic images, thus providing both tools and continued access to data for forensic practitioners in a variety of settings.

  9. Can multi-slice or navigator-gated R2* MRI replace single-slice breath-hold acquisition for hepatic iron quantification?

    Energy Technology Data Exchange (ETDEWEB)

    Loeffler, Ralf B.; McCarville, M.B.; Song, Ruitian; Hillenbrand, Claudia M. [St. Jude Children' s Research Hospital, Diagnostic Imaging, Memphis, TN (United States); Wagstaff, Anne W. [St. Jude Children' s Research Hospital, Diagnostic Imaging, Memphis, TN (United States); Rhodes College, Memphis, TN (United States); University of Alabama at Birmingham School of Medicine, Birmingham, AL (United States); Smeltzer, Matthew P. [St. Jude Children' s Research Hospital, Department of Biostatistics, Memphis, TN (United States); University of Memphis, Division of Epidemiology, Biostatistics, and Environmental Health, School of Public Health, Memphis, TN (United States); Krafft, Axel J. [St. Jude Children' s Research Hospital, Diagnostic Imaging, Memphis, TN (United States); University Hospital Center Freiburg, Department of Radiology, Freiburg (Germany); Hankins, Jane S. [St. Jude Children' s Research Hospital, Department of Hematology, Memphis, TN (United States)

    2017-01-15

    Liver R2* values calculated from multi-gradient echo (mGRE) magnetic resonance images (MRI) are strongly correlated with hepatic iron concentration (HIC) as shown in several independently derived biopsy calibration studies. These calibrations were established for axial single-slice breath-hold imaging at the location of the portal vein. Scanning in multi-slice mode makes the exam more efficient, since whole-liver coverage can be achieved with two breath-holds and the optimal slice can be selected afterward. Navigator echoes remove the need for breath-holds and allow use in sedated patients. To evaluate if the existing biopsy calibrations can be applied to multi-slice and navigator-controlled mGRE imaging in children with hepatic iron overload, by testing if there is a bias-free correlation between single-slice R2* and multi-slice or multi-slice navigator controlled R2*. This study included MRI data from 71 patients with transfusional iron overload, who received an MRI exam to estimate HIC using gradient echo sequences. Patient scans contained 2 or 3 of the following imaging methods used for analysis: single-slice images (n = 71), multi-slice images (n = 69) and navigator-controlled images (n = 17). Small and large blood corrected region of interests were selected on axial images of the liver to obtain R2* values for all data sets. Bland-Altman and linear regression analysis were used to compare R2* values from single-slice images to those of multi-slice images and navigator-controlled images. Bland-Altman analysis showed that all imaging method comparisons were strongly associated with each other and had high correlation coefficients (0.98 ≤ r ≤ 1.00) with P-values ≤0.0001. Linear regression yielded slopes that were close to 1. We found that navigator-gated or breath-held multi-slice R2* MRI for HIC determination measures R2* values comparable to the biopsy-validated single-slice, single breath-hold scan. We conclude that these three R2* methods can be

  10. Flat-panel volume CT: fundamental principles, technology, and applications.

    Science.gov (United States)

    Gupta, Rajiv; Cheung, Arnold C; Bartling, Soenke H; Lisauskas, Jennifer; Grasruck, Michael; Leidecker, Christianne; Schmidt, Bernhard; Flohr, Thomas; Brady, Thomas J

    2008-01-01

    Flat-panel volume computed tomography (CT) systems have an innovative design that allows coverage of a large volume per rotation, fluoroscopic and dynamic imaging, and high spatial resolution that permits visualization of complex human anatomy such as fine temporal bone structures and trabecular bone architecture. In simple terms, flat-panel volume CT scanners can be thought of as conventional multidetector CT scanners in which the detector rows have been replaced by an area detector. The flat-panel detector has wide z-axis coverage that enables imaging of entire organs in one axial acquisition. Its fluoroscopic and angiographic capabilities are useful for intraoperative and vascular applications. Furthermore, the high-volume coverage and continuous rotation of the detector may enable depiction of dynamic processes such as coronary blood flow and whole-brain perfusion. Other applications in which flat-panel volume CT may play a role include small-animal imaging, nondestructive testing in animal survival surgeries, and tissue-engineering experiments. Such versatility has led some to predict that flat-panel volume CT will gain importance in interventional and intraoperative applications, especially in specialties such as cardiac imaging, interventional neuroradiology, orthopedics, and otolaryngology. However, the contrast resolution of flat-panel volume CT is slightly inferior to that of multidetector CT, a higher radiation dose is needed to achieve a comparable signal-to-noise ratio, and a slower scintillator results in a longer scanning time.

  11. Clinical application of FDG-PET/CT in metastatic infections.

    Science.gov (United States)

    Kouijzer, Ilse J; Vos, Fidel J; Bleeker-Rovers, Chantal P; Oyen, Wim J

    2017-06-01

    FDG-PET/CT has proven its clinical value and cost-effectiveness in diagnosing metastatic infections in patients with Gram-positive bacteremia. In identification of metastatic foci, FDG-PET/CT is useful as a screening method when localizing symptoms are absent because it provides whole-body coverage. FDG-PET/CT detects early metabolic activity rather than the late anatomical changes as visualized by computed tomography and magnetic resonance imaging. FDG-PET/CT allows more precise localization of infection within a shorter time span between injection and diagnosis as compared to conventional nuclear imaging. This review focuses on the clinical application of imaging of metastatic infectious diseases, with an emphasis on FDG-PET/CT putting it in perspective with other imaging modalities.

  12. Spiral CT pneumocolon: applications, status and limitations.

    Science.gov (United States)

    Harvey, C J; Renfrew, I; Taylor, S; Gillams, A R; Lees, W R

    2001-01-01

    CT pneumocolon is a promising new technique in the diagnosis and management of colon pathology. CT pneumocolon can detect (sensitivity >95%) and stage (accuracy 79%) colorectal cancer and is very accurate in the differentiation of malignant from benign colonic pathologies. It has excellent detection rates for polyps >10 mm in diameter. Several studies using 3D virtual colonoscopy have already proven its high sensitivity and specificity in polyp detection making this technique robust as a screening tool. The combined results for virtual colonoscopy, from all centres, show a sensitivity of >85% in the detection of polyps 10 mm or greater in size, 70-80% for 5-9 mm polyps and an overall specificity of 90%. CT pneumocolon is a safe, non-invasive and cost-effective method for detecting colonic carcinomas and adenomas and correctly identifying which patients need further colonoscopy. The technique is quick, well tolerated and non-operator dependent. It can also image the proximal colon when distal stenoses prevent endoscopic and barium examination. CT pneumocolon is able to identify the features and complications of inflammatory bowel disease. Further research is warranted to fully assess its impact in terms of a screening tool, acceptability, availability and cost benefit.

  13. Spiral CT pneumocolon: applications, status and limitations

    Energy Technology Data Exchange (ETDEWEB)

    Harvey, C.J. [Department of Academic Imaging, University College London (United Kingdom); Department of Imaging, Hammersmith Hospital, London (United Kingdom); Renfrew, I.; Taylor, S.; Gillams, A.R.; Lees, W.R. [Department of Academic Imaging, University College London (United Kingdom)

    2001-09-01

    CT pneumocolon is a promising new technique in the diagnosis and management of colon pathology. CT pneumocolon can detect (sensitivity >95%) and stage (accuracy 79%) colorectal cancer and is very accurate in the differentiation of malignant from benign colonic pathologies. It has excellent detection rates for polyps >10 mm in diameter. Several studies using 3D virtual colonoscopy have already proven its high sensitivity and specificity in polyp detection making this technique robust as a screening tool. The combined results for virtual colonoscopy, from all centres, show a sensitivity of >85% in the detection of polyps 10 mm or greater in size, 70-80% for 5-9 mm polyps and an overall specificity of 90%. CT pneumocolon is a safe, non-invasive and cost-effective method for detecting colonic carcinomas and adenomas and correctly identifying which patients need further colonoscopy. The technique is quick, well tolerated and non-operator dependent. It can also image the proximal colon when distal stenoses prevent endoscopic and barium examination. CT pneumocolon is able to identify the features and complications of inflammatory bowel disease. Further research is warranted to fully assess its impact in terms of a screening tool, acceptability, availability and cost benefit. (orig.)

  14. Metrology, applications and methods with high energy CT systems

    Energy Technology Data Exchange (ETDEWEB)

    Uhlmann, N.; Voland, V.; Salamon, M.; Hebele, S.; Boehnel, M.; Reims, N.; Schmitt, M.; Kasperl, S. [Fraunhofer IIS/EZRT, Development Center X-Ray Technology, Flugplatzstrasse 75, 90768 Fürth (Germany); Hanke, R. [Chair of X-ray Microscopy, University of Würzburg - Physics and Astronomy (Germany)

    2014-02-18

    The increase of Computed Tomography (CT) as an applicable metrology and Non Destructive Testing (NDT) method raises interest on developing the application fields to larger objects, which were rarely used in the past due to their requirements on the imaging system. Especially the classical X-ray generation techniques based on standard equipment restricted the applications of CT to typical material penetration lengths of only a few cm of steel. Even with accelerator technology that offers a suitable way to overcome these restrictions just the 2D radioscopy technique found a widespread application. Beside the production and detection of photons in the MeV range itself, the achievable image quality is limited using standard detectors due to the dominating absorption effect of Compton Scattering at high energies. Especially for CT reconstruction purposes these effects have to be considered on the development path from 2D to 3D imaging. Most High Energy CT applications are therefore based on line detectors shielding scattered radiation to a maximum with an increase in imaging quality but with time consuming large volume scan capabilities. In this contribution we present the High-Energy X-ray Imaging project at the Fraunhofer Development Centre for X-ray Technology with the characterization and the potential of the CT-system according to metrological and other application capabilities.

  15. CT Perfusion of the Liver: Principles and Applications in Oncology

    Science.gov (United States)

    Kim, Se Hyung; Kamaya, Aya

    2014-01-01

    With the introduction of molecularly targeted chemotherapeutics, there is an increasing need for defining new response criteria for therapeutic success because use of morphologic imaging alone may not fully assess tumor response. Computed tomographic (CT) perfusion imaging of the liver provides functional information about the microcirculation of normal parenchyma and focal liver lesions and is a promising technique for assessing the efficacy of various anticancer treatments. CT perfusion also shows promising results for diagnosing primary or metastatic tumors, for predicting early response to anticancer treatments, and for monitoring tumor recurrence after therapy. Many of the limitations of early CT perfusion studies performed in the liver, such as limited coverage, motion artifacts, and high radiation dose of CT, are being addressed by recent technical advances. These include a wide area detector with or without volumetric spiral or shuttle modes, motion correction algorithms, and new CT reconstruction technologies such as iterative algorithms. Although several issues related to perfusion imaging—such as paucity of large multicenter trials, limited accessibility of perfusion software, and lack of standardization in methods—remain unsolved, CT perfusion has now reached technical maturity, allowing for its use in assessing tumor vascularity in larger-scale prospective clinical trials. In this review, basic principles, current acquisition protocols, and pharmacokinetic models used for CT perfusion imaging of the liver are described. Various oncologic applications of CT perfusion of the liver are discussed and current challenges, as well as possible solutions, for CT perfusion are presented. © RSNA, 2014 Online supplemental material is available for this article. PMID:25058132

  16. DREAM - A Novel Approach for Robust, Ultra-Fast, Multi-Slice B1 Mapping

    NARCIS (Netherlands)

    Nehrke, K.; Boernert, P.

    2012-01-01

    Fast and robust in vivo B1 mapping is an essential prerequisite forquantitative MRI or multi-element transmit applications like RF-shimming or accelerated multi-dimensional RF pulses. However, especially at higher field strength, the acquisition speed of current B1-mapping approaches is typicall

  17. Whole-body diffusion imaging applying simultaneous multi-slice excitation

    Energy Technology Data Exchange (ETDEWEB)

    Kenkel, David; Wurning, M.C.; Filli, L.; Ulbrich, E.J.; Boss, A. [Universitaetsspital Zuerich (Switzerland). Diagnostische und Interventionelle Radiologie; Runge, V.M. [Univ. Hospital Zurich (Switzerland). Dept. of Neuroradiology; Beck, T. [Siemens Healthcare GmbH, Erlangen (Germany)

    2016-04-15

    The purpose of this study was to examine the feasibility of a fast protocol for whole-body diffusion-weighted imaging (WB-DWI) using a slice-accelerated echo-planar sequence, which, when using comparable image acquisition parameters, noticeably reduces measurement time compared to a conventional WB-DWI protocol. A single-shot echo-planar imaging sequence capable of simultaneous slice excitation and acquisition was optimized for WB-DWI on a 3 T MR scanner, with a comparable conventional WB-DWI protocol serving as the reference standard. Eight healthy individuals and one oncologic patient underwent WB-DWI. Quantitative analysis was carried out by measuring the apparent diffusion coefficient (ADC) and its coefficient of variation (CV) in different organs. Image quality was assessed qualitatively by two independent radiologists using a 4-point Likert scale. Using our proposed protocol, the scan time of the WB-DWI measurement was reduced by up to 25.9 %. Both protocols, the slice-accelerated protocol and the conventional protocol, showed comparable image quality without statistically significant differences in the reader scores. Similarly, no significant differences of the ADC values of parenchymal organs were found, whereas ADC values of brain tissue were slightly higher in the slice-accelerated protocol. It was demonstrated that slice-accelerated DWI can be applied to WB-DWI protocols with the potential to greatly reduce the required measurement time, thereby substantially increasing clinical applicability.

  18. Global and regional left ventricular function: a comparison between gated SPECT, 2D echocardiography and multi-slice computed tomography

    Energy Technology Data Exchange (ETDEWEB)

    Henneman, Maureen M.; Bax, Jeroen J.; Holman, Eduard R. [Leiden University Medical Center, Department of Cardiology, Leiden (Netherlands); Schuijf, Joanne D.; Jukema, J.W.; Wall, Ernst E. van der [Leiden University Medical Center, Department of Cardiology, Leiden (Netherlands); The Interuniversity Cardiology Institute of the Netherlands, Utrecht (Netherlands); Stokkel, Marcel P.M. [Leiden University Medical Center, Department of Nuclear Medicine, Leiden (Netherlands); Lamb, Hildo J.; Roos, Albert de [Leiden University Medical Center, Department of Radiology, Leiden (Netherlands)

    2006-12-15

    Global and regional left ventricular (LV) function are important indicators of the cardiac status in patients with coronary artery disease (CAD). Therapy and prognosis are to a large extent dependent on LV function. Multi-slice computed tomography (MSCT) has already earned its place as an imaging modality for non-invasive assessment of the coronary arteries, but since retrospective gating to the patient's ECG is performed, information on LV function can be derived. In 49 patients with known or suspected CAD, coronary angiography with MSCT imaging was performed, in addition to gated SPECT and 2D echocardiography. LV end-diastolic and LV end-systolic volumes and LV ejection fraction were analysed with dedicated software (CMR Analytical Software System, Medis, Leiden, The Netherlands for MSCT; gated SPECT by QGS, Cedars-Sinai Medical Center, Los Angeles, CA, USA), and by the biplane Simpson's rule for 2D echocardiography. Regional wall motion was evaluated according to a 17-segment model and a three-point score system. Correlations were fairly good between gated SPECT and MSCT (LVEDV: r=0.65; LVESV: r=0.63; LVEF: r=0.60), and excellent between 2D echocardiography and MSCT (LVEDV: r=0.92; LVESV: r=0.93; LVEF: r=0.80). Agreement for regional wall motion was 95% ({kappa}=0.66) between gated SPECT and MSCT, and 96% ({kappa}=0.73) between 2D echocardiography and MSCT. Global and regional LV function and LV volumes can be adequately assessed with MSCT. Correlations with 2D echocardiography are stronger than with gated SPECT. (orig.)

  19. Accuracy of Multi-Slice Spiral Computed Tomography for Preoperative Tumor Node Metastasis (TNM) Staging of Colorectal Carcinoma.

    Science.gov (United States)

    Bai, Rong-Jie; Ren, Shao-Hua; Jiang, Hui-Jie; Li, Jin-Ping; Liu, Xiao-Cheng; Xue, Li-Ming

    2017-07-17

    BACKGROUND With the advances in imaging technologies, multi-slice spiral computed tomography (MSCT) has demonstrated superiority in the diagnosis and staging of colorectal carcinoma. In the current study, preoperative TNM staging of colorectal carcinoma by using MSCT was conducted and compared with the corresponding postoperative pathological examination findings, in order to evaluate the accuracy of preoperative MSCT for TNM staging. MATERIAL AND METHODS Combinations of biphasic or triphasic enhanced-phase MSCT scans were obtained for 76 patients with colorectal carcinoma, and the TNM stage was determined based on imaging reconstruction from various angles and perspectives to display the size, location, and affected range of tumors. The preoperative TNM stage was compared with the postoperative pathological stage, and the consistency between the 2 methods was tested by the k test using SPSS 17.0 software. RESULTS Among the different combinations of enhanced-phase MSCT scanning, triphasic MSCT imaging, comprising the arterial, portal venous, and delayed phases, showed the highest accuracy rates, at 81.6% (62/76), 82.89% (63/76), and 96.1% (73/76) for T, N, and M staging, respectively, with k values of 0.72, 0.65, and 0.56, respectively, indicating consistency with the postoperative pathological staging. CONCLUSIONS Combined MSCT scanning comprising the arterial phase, portal venous phase, and delayed phase showed satisfying consistency with the postoperative pathological analysis results for TNM staging of colorectal carcinoma. Thus, MSCT is an important clinical value for improving the accuracy of TNM staging and for planning the appropriate colorectal cancer treatment.

  20. Clinical application of hepatic CT perfusion

    Institute of Scientific and Technical Information of China (English)

    Liang Zhong; Wen-Jing Wang; Jian-Rong Xu

    2009-01-01

    Complicated changes occur in hemodynamics of hepatic artery and vein, and portal vein under various kinds of pathologic status because of distinct double hepatic blood supply. This article reviews the clinical application of hepatic computed tomography perfusion in some liver diseases.

  1. Use of various CT imaging methods for diagnosis of acute ischemic cerebrovascular disease

    Institute of Scientific and Technical Information of China (English)

    Gang Wang; Xue Cheng; Xianglin Zhang

    2013-01-01

    Thirty-four patients with cerebral infarction and 18 patients with transient ischemic attack were examined by multi-slice spiral CT scan, CT perfusion imaging, and CT angiography within 6 hours after onset. By CT perfusion imaging, 29 cases in the cerebral infarction group and 10 cases in the transient ischemic attack group presented with abnormal blood flow perfusion, which corresponded to the clinical symptoms. By CT angiography, various degrees of vascular stenosis could be detected in 41 patients, including 33 in the cerebral infarction group and eight in the transient ischemic attack group. The incidence of intracranial artery stenosis was higher than that of extracranial artery stenosis. The intracranial artery stenosis was located predominantly in the middle cerebral artery and carotid artery siphon, while the extracranial artery stenosis occurred mainly in the bifurcation of the common carotid artery and the opening of the vertebral artery. There were 34 cases (83%) with convict vascular stenosis and perfusion abnormalities, and five cases (45%) with perfusion abnormalities but without convict vascular stenosis. The incidence of cerebral infarction in patients with National Institutes of Health Stroke Scale scores ≥ 5 points during onset was significantly higher than that in patients with National Institutes of Health Stroke Scale scores < 5 points. These experimental findings indicate that the combined application of various CT imaging methods allows early diagnosis of acute ischemic cerebrovascular disease, which can comprehensively analyze the pathogenesis and severity of acute ischemic cerebrovascular disease at the morphological and functional levels.

  2. Exploiting sparsity and low-rank structure for the recovery of multi-slice breast MRIs with reduced sampling error.

    Science.gov (United States)

    Yin, X X; Ng, B W-H; Ramamohanarao, K; Baghai-Wadji, A; Abbott, D

    2012-09-01

    It has been shown that, magnetic resonance images (MRIs) with sparsity representation in a transformed domain, e.g. spatial finite-differences (FD), or discrete cosine transform (DCT), can be restored from undersampled k-space via applying current compressive sampling theory. The paper presents a model-based method for the restoration of MRIs. The reduced-order model, in which a full-system-response is projected onto a subspace of lower dimensionality, has been used to accelerate image reconstruction by reducing the size of the involved linear system. In this paper, the singular value threshold (SVT) technique is applied as a denoising scheme to reduce and select the model order of the inverse Fourier transform image, and to restore multi-slice breast MRIs that have been compressively sampled in k-space. The restored MRIs with SVT for denoising show reduced sampling errors compared to the direct MRI restoration methods via spatial FD, or DCT. Compressive sampling is a technique for finding sparse solutions to underdetermined linear systems. The sparsity that is implicit in MRIs is to explore the solution to MRI reconstruction after transformation from significantly undersampled k-space. The challenge, however, is that, since some incoherent artifacts result from the random undersampling, noise-like interference is added to the image with sparse representation. These recovery algorithms in the literature are not capable of fully removing the artifacts. It is necessary to introduce a denoising procedure to improve the quality of image recovery. This paper applies a singular value threshold algorithm to reduce the model order of image basis functions, which allows further improvement of the quality of image reconstruction with removal of noise artifacts. The principle of the denoising scheme is to reconstruct the sparse MRI matrices optimally with a lower rank via selecting smaller number of dominant singular values. The singular value threshold algorithm is performed

  3. Virtopsy post-mortem multi-slice computed tomograhy (MSCT) and magnetic resonance imaging (MRI) demonstrating descending tonsillar herniation: comparison to clinical studies

    Energy Technology Data Exchange (ETDEWEB)

    Aghayev, Emin; Yen, Kathrin; Thali, Michael; Jackowski, Christian; Dirnhofer, Richard [Institute of Forensic Medicine, University of Bern, IRM-Buehlstrasse 20, 3012, Bern (Switzerland); Sonnenschein, Martin [Institute of Diagnostic Radiology, Inselspital, 3010, Bern (Switzerland); Ozdoba, Christoph [Department of Neuroradiology, Inselspital, 3010, Bern (Switzerland)

    2004-07-01

    Descending cerebellar tonsillar herniation is a serious and common complication of intracranial mass lesions. We documented three cases of fatal blunt head injury using post-mortem multi-slice computed tomography (MSCT) and magnetic resonance imaging (MRI). The results showed massive bone and soft-tissue injuries of the head and signs of high intracranial pressure with herniation of the cerebellar tonsils. The diagnosis of tonsillar herniation by post-mortem radiological examination was performed prior to autopsy. This paper describes the detailed retrospective evaluation of the position of the cerebellar tonsils in post-mortem imaging in comparison to clinical studies. (orig.)

  4. 胃肿瘤CT灌注成像的临床研究%Clinical study of stomach neoplasm CT perfusion imaging

    Institute of Scientific and Technical Information of China (English)

    Zhiyong Li; Ying Ge; Jinghong Liu; Keli Wang; Jianlin Wu

    2009-01-01

    Objection: The purpose of this study is preliminarily to discuss stomach perfusion imaging technique with Multi-slice CT and its clinical application value in stomach neoplasm. Methods: Fifteen patients with known stomach neoplasm performed perfusion imaging with 4 or 16 slice CT. Performing peffusion imaging in central slice of neoplasm, using CT cine scan, slice thick 10 mm/2i; with high pressure syringe, injecting quickly from right elbow-front vein, dosage 45-50 mL, injec-tion rate 3.5-4.0 mL/s, scanning delay time 5 s, scanning total time 45 s. We performed perfusion CT post-processing using pancreatic mode of perfusion CT software. Blood flow (BF), blood volume (BV), mean transit time (MTT), and permeability surface (PS) of gastric wall and tumor were computed for every case. Results: BF, BV, MTT and PS of gastric tumor were 116.68±90.09 mL/(min .100 g), 9.57±8.12 mL/100 g, 10.07± 7.74 s, 20.78±19.68 mL/ (min .100 g), respectively. The P values for each CT perfusion parameters between gastdc tumor and normal gastric wall were 0.001,0.021, 0.155 and 0.031,respectively. Conclusion: Perfusion CT can provide hemodynamics of gastdc tumors and play a key role in the diagnosis of gastric tumors. It's clinical application prospect will be fully broad.

  5. Reconstruction of a ring applicator using CT imaging: impact of the reconstruction method and applicator orientation

    DEFF Research Database (Denmark)

    Hellebust, Taran Paulsen; Tanderup, Kari; Bergstrand, Eva Stabell;

    2007-01-01

    The purpose of this study is to investigate whether the method of applicator reconstruction and/or the applicator orientation influence the dose calculation to points around the applicator for brachytherapy of cervical cancer with CT-based treatment planning. A phantom, containing a fixed ring...

  6. New trends in CT. Applications in oncology; Progres en tomodensitometrie. Applications en cancerologie

    Energy Technology Data Exchange (ETDEWEB)

    Coulomb, M.; Ferretti, G.; Ranchoup, Y.; Blanc, F.; Albano, G. [Hopital Albert-Michallon, 38 - La Tronche (France)

    1995-12-01

    Since 1992, spiral CT scanners replace conventional CT units in radiology departments. In the first part of this paper, we present some technical considerations concerning spiral CT (continuous rotation and emission of the source-detector; continuous translation of the patient at a constant rate through the gantry), as well as advantages and limitations of voluminal acquisition. The main advantages can be summarized as: reduction of the acquisition time, optimization of contrast enhancement with intravenous opacification, and post processing allowing retrospective creation of overlapping images, multiplanar reconstructions, and 3-D reconstructions. Spiral CT improves lesions detection and characterization. Disadvantages are due to contrast media injection and radiation exposure. Then we describe clinical applications in the carcinological field concerning pharyngo-laryngeal tumors, bronchogenic carcinoma, mediastinal tumors, pulmonary nodules, sub-diaphragmatic tumors. However, tumors of brain, spine, bone, and soft tissue are better explored with MRI. Authors conclude on the future improvements of spiral CT. (authors). 15 refs., 3 figs.

  7. Thoracic applications of dual-source CT technology.

    Science.gov (United States)

    Boroto, Kahimano; Remy-Jardin, Martine; Flohr, Thomas; Faivre, Jean-Baptiste; Pansini, Vittorio; Tacelli, Nunzia; Schmidt, Bernhard; Gorgos, Andrei; Remy, Jacques

    2008-12-01

    Among the various imaging modalities available, CT has remained over time the core imaging technique for the evaluation of respiratory disorders. The recent advent of dual-source CT offers innovative approaches to investigate thoracic diseases, based on the use of one or two tubes as well as single or dual energy to scan the entire thorax. Two major options can be used in clinical practice with promising results. Dual source, single-energy scanning allows scanning of the entire thorax with ultra-high temporal resolution which opens the field of integrated cardiothoracic imaging without ECG gating as well as optimized evaluation of pediatric and adult patients with limited ability to cooperate. Dual-source, dual-energy acquisitions represent another very innovative means of investigating respiratory disorders, adding tissue characterization and functional analysis to morphological evaluation. The purpose of this review article is to provide results on preliminary experiences with the above-mentioned scanning conditions with dual-source CT and to envisage potential forthcoming applications in the field of thoracic imaging.

  8. Combination of CT scanning and fluoroscopy imaging on a flat-panel CT scanner

    Science.gov (United States)

    Grasruck, M.; Gupta, R.; Reichardt, B.; Suess, Ch.; Schmidt, B.; Stierstorfer, K.; Popescu, S.; Brady, T.; Flohr, T.

    2006-03-01

    We developed and evaluated a prototype flat-panel detector based Volume CT (fpVCT) scanner. The fpVCT scanner consists of a Varian 4030CB a-Si flat-panel detector mounted in a multi slice CT-gantry (Siemens Medical Solutions). It provides a 25 cm field of view with 18 cm z-coverage at the isocenter. In addition to the standard tomographic scanning, fpVCT allows two new scan modes: (1) fluoroscopic imaging from any arbitrary rotation angle, and (2) continuous, time-resolved tomographic scanning of a dynamically changing viewing volume. Fluoroscopic imaging is feasible by modifying the standard CT gantry so that the imaging chain can be oriented along any user-selected rotation angle. Scanning with a stationary gantry, after it has been oriented, is equivalent to a conventional fluoroscopic examination. This scan mode enables combined use of high-resolution tomography and real-time fluoroscopy with a clinically usable field of view in the z direction. The second scan mode allows continuous observation of a timeevolving process such as perfusion. The gantry can be continuously rotated for up to 80 sec, with the rotation time ranging from 3 to 20 sec, to gather projection images of a dynamic process. The projection data, that provides a temporal log of the viewing volume, is then converted into multiple image stacks that capture the temporal evolution of a dynamic process. Studies using phantoms, ex vivo specimens, and live animals have confirmed that these new scanning modes are clinically usable and offer a unique view of the anatomy and physiology that heretofore has not been feasible using static CT scanning. At the current level of image quality and temporal resolution, several clinical applications such a dynamic angiography, tumor enhancement pattern and vascularity studies, organ perfusion, and interventional applications are in reach.

  9. Diagnostic Applications of Cone-Beam CT for Periodontal Diseases

    OpenAIRE

    AlJehani, Yousef A.

    2014-01-01

    Objectives. This paper aims to review the diagnostic application of cone beam computed tomography (CBCT) in the field of periodontology. Data. Original articles that reported on the use of CBCT for periodontal disease diagnosis were included. Sources. MEDLINE (1990 to January 2014), PubMed (using medical subject headings), and Google Scholar were searched using the following terms in different combinations: “CBCT,” “volumetric CT,” “periodontal disease ,” and “periodontitis.” This was supplem...

  10. Clinical application of CT and CT-guided percutaneous transthoracic needle biopsy in patients with indeterminate pulmonary nodules

    Energy Technology Data Exchange (ETDEWEB)

    Cardoso, Luciana Vargas; Souza Júnior, Arthur Soares, E-mail: fabianonatividade@terra.com.br [Rio Preto-Ultra-X Radiological Diagnosis Institute, São José do Rio Preto, SP (Brazil)

    2014-07-15

    Objective: To investigate the clinical application of CT and CT-guided percutaneous transthoracic needle biopsy (CT-PTNB) in patients with indeterminate pulmonary nodules (IPNs). Methods: We retrospectively studied 113 patients with PNs undergoing CT and CT-PTNB. Variables such as gender, age at diagnosis, smoking status, CT findings, and CT-PTNB techniques were analyzed. Data analysis was performed with the Student's t-test for independent samples the chi-square test, and normal approximation test for comparison of two proportions. Results: Of the 113 patients studied, 68 (60.2%) were male and 78 (69%) were smokers. The diameter of malignant lesions ranged from 2.6 cm to 10.0 cm. Most of the IPNs (85%) were located in the peripheral region. The biopsied IPNs were found to be malignant in 88 patients (77.8%) and benign in 25 (22.2%). Adenocarcinoma was the most common malignant tumor, affecting older patients. The IPN diameter was significantly greater in patients with malignant PNs than in those with benign IPNs (p < 0.001). Having regular contour correlated significantly with an IPN being benign (p = 0.022), whereas spiculated IPNs and bosselated IPNs were more often malignant (in 50.7% and 28.7%, respectively). Homogeneous attenuation and necrosis were more common in patients with malignant lesions (51.9% and 26.9%, respectively). Conclusions: In our sample, CT and CT-PTNB were useful in distinguishing between malignant and benign IPNs. Advanced age and smoking were significantly associated with malignancy. Certain CT findings related to IPNs (larger diameter, spiculated borders, homogeneous attenuation, and necrosis) were associated with malignancy. (author)

  11. Detachment within subducted continental crust and multi-slice successive exhumation of ultrahigh-pressure metamorphic rocks: Evidence from the Dabie-Sulu orogenic belt

    Institute of Scientific and Technical Information of China (English)

    LIU YiCan; LI ShuGuang

    2008-01-01

    Although tectonic models were presented for exhumation of ultrahigh-pressure (UHP) metamorphic rocks during the continental collision, there is increasing evidence for the decoupling between crustal slices at various depths within deeply subducted continental crust. This lends support to the multi-slice successive exhumation model of the UHP metamorphic rocks in the Dabie-Sulu orogen. The available evidence is summarized as follows: (1) the low-grade metamorphic slices, which have geotectonic af-finity to the South China Block and part of them records the Triassic metamorphism, occur in the northern margin of the Dabie-Sulu UHP metamorphic zone, suggesting decoupling of the upper crust from the underlying basement during the initial stages of continental subduction; (2) the Dabie and Sulu HP to UHP metamorphic zones comprise several HP to UHP slices, which have an increased trend of metamorphic grade from south to north but a decreased trend of peak metamorphic ages corre-spondingly; and (3) the Chinese Continental Science Drilling (CCSD) project at Donghai in the Sulu orogen reveals that the UHP metamorphic zone is composed of several stacked slices, which display distinctive high and low radiogenic Pb from upper to lower parts in the profile, suggesting that these UHP crustal slices were derived from the subducted upper and middle crusts, respectively. Detachment surfaces within the deeply subducted crust may occur either along an ancient fault as a channel of fluid flow, which resulted in weakening of mechanic strength of the rocks adjacent to the fault due to fluid-rock interaction, or along the low-viscosity zones which resulted from variations of geotherms and lithospheric compositions at different depths. The multi-slice successive exhumation model is different from the traditional exhumation model of the UHP metamorphic rocks in that the latter as-sumes the detachment of the entire subducted continental crust from the underlying mantle lithosphere and its

  12. Abdominal CT enterography as an imaging tool for chronic diarrhea: Review of technique and diagnostic criteria

    OpenAIRE

    Mona El-Kalioubie; Rasha Ali

    2015-01-01

    Purpose: Our aim was to evaluate the role of multi-slice CT enterography in chronic diarrhea and its degree of correlation with endoscopy and histopathology. Materials and methods: 50 patients with chronic diarrhea (23 Crohn’s disease, 3 ulcerative colitis, 5 Tuberculous enteritis, 1 Entamoeba infestation, 4 Celiac disease, 5 lymphoma and 10 miscellaneous) were evaluated by CT enterography. Quantitative image analysis included evaluation of bowel caliber and wall thickness. Qualitative ana...

  13. The clinical application value of CT reexamination in the patients with occult pulmonary contusion%CT复查在首诊为隐匿性肺挫伤患者中的应用价值

    Institute of Scientific and Technical Information of China (English)

    向前; 王凌; 孔德会; 李全

    2014-01-01

    目的:评价多层螺旋CT(MSCT)在隐匿性肺挫伤(OPC)患者随访复查中的临床价值。方法对35例首诊确定为OPC患者的CT随访资料及临床转归进行回顾性分析,观察CT图像上肺挫伤病变的范围、密度演变情况,患者合并感染及临床转归情况,判断CT复查在OPC患者中的应用价值。结果所有35例OPC患者均在伤后1~90 d内进行1~4次CT复查,其中13例患者出现挫伤范围的扩大,主要出现在伤后1~2 d;7例继发肺炎,主要出现在伤后7~14 d,1例发展为急性呼吸窘迫综合征(ARDS),1例患者继发脓胸。结论首诊为OPC的患者病情可能继续发展,MSCT能较全面地判断评价OPC患者肺部病变的演变情况,应当作为OPC患者重要的随访复查手段。%Objective To evaluate the clinical application value of multi-slice spiral CT (MSCT) reexamination in the patients with occult pulmonary contusion (OPC). Methods The CT and clinical data of 35 patients with OPC was retrospectively analyzed. Analyze the scopes and densities of contusions, contusions′ variation with time and pa-tients clinical prognosis in order to evaluate the clinical application value of MSCT reexamination in the patients with OPC. Results CT reexamination was performed in 1-90 days after injury. The scope of pulmonary in 13 patients contusion enlarged,which appeared mainly in 1-2 days after injury. Pneumonia was found in 7 patients, which mainly appeared in 7-14 days after injury. One case developed to acute respiratory distress syndrome (ARDS), and one pa-tients developed to empyema. Conclusion The condition of OPC may aggravate. MSCT could comprehensively evalu-ate the changes of OPC, which should be a good choice for follow-up examination of patients with OPC.

  14. Diagnostic Applications of Cone-Beam CT for Periodontal Diseases

    Directory of Open Access Journals (Sweden)

    Yousef A. AlJehani

    2014-01-01

    Full Text Available Objectives. This paper aims to review the diagnostic application of cone beam computed tomography (CBCT in the field of periodontology. Data. Original articles that reported on the use of CBCT for periodontal disease diagnosis were included. Sources. MEDLINE (1990 to January 2014, PubMed (using medical subject headings, and Google Scholar were searched using the following terms in different combinations: “CBCT,” “volumetric CT,” “periodontal disease ,” and “periodontitis.” This was supplemented by hand-searching in peer-reviewed journals and cross-referenced with the articles accessed. Conclusions. Bony defects, caters, and furcation involvements seem to be better depicted on CBCT, whereas bone quality and periodontal ligament space scored better on conventional intraoral radiography. CBCT does not offer a significant advantage over conventional radiography for assessing the periodontal bone levels.

  15. Multi-slice Spiral Computed Tomography Manifestations of Brain and Cerebral Hemodynamics in Chronic Mountain Sickness%慢性高原病脑部MSCT表现与血流动力学研究

    Institute of Scientific and Technical Information of China (English)

    王铎尧; 鲍海华; 赵希鹏; 李文方

    2011-01-01

    significantly highcr in CMS group than that in normal group (t=4. 551, P<0. 01 and t= 2. 898,P<0. 01 , respectively) . In CMS group , the CT value of superior sagittal sinus and bilateral middle cerebral artery with hemoglobin level (r=0. 758 and r=0. 740 , both P<0. 01). (2) The changes of CBF were obviously in grey matter than in white matter. In grey matter,CBF reduced more in CMS group than in normal group(P<0. 01). TTP in grey matter prolonged obviously in CMS group (P<0. 05 ). MTT in grey matter and white matter both prolonged obviously in CMS group (P<0. 01 ). Conclusion Multi-slice spiral CT is a valuable tool to study the state of the whole brain and the cercbral hemodvnamics in CMS patients.

  16. [Application of computed tomography (CT) examination for forensic medicine].

    Science.gov (United States)

    Urbanik, Andrzej; Chrzan, Robert

    2013-01-01

    The aim of the study is to present a own experiences in usage of post mortem CT examination for forensic medicine. With the help of 16-slice CT scanner 181 corpses were examined. Obtained during acquisition imaging data are later developed with dedicated programmes. Analyzed images were extracted from axial sections, multiplanar reconstructions as well as 3D reconstructions. Gained information helped greatly when classical autopsy was performed by making it more accurate. A CT scan images recorded digitally enable to evaluate corpses at any time, despite processes of putrefaction or cremation. If possible CT examination should precede classical autopsy.

  17. Neural network and its application to CT imaging

    Energy Technology Data Exchange (ETDEWEB)

    Nikravesh, M.; Kovscek, A.R.; Patzek, T.W. [Lawrence Berkeley National Lab., CA (United States)] [and others

    1997-02-01

    We present an integrated approach to imaging the progress of air displacement by spontaneous imbibition of oil into sandstone. We combine Computerized Tomography (CT) scanning and neural network image processing. The main aspects of our approach are (I) visualization of the distribution of oil and air saturation by CT, (II) interpretation of CT scans using neural networks, and (III) reconstruction of 3-D images of oil saturation from the CT scans with a neural network model. Excellent agreement between the actual images and the neural network predictions is found.

  18. Reconstruction of a ring applicator using CT imaging: impact of the reconstruction method and applicator orientation

    Energy Technology Data Exchange (ETDEWEB)

    Hellebust, Taran Paulsen [Department of Medical Physics, Rikshospital-Radiumhospital Medical Center, Oslo (Norway); Tanderup, Kari [Department of Oncology, Aarhus University Hospital, Aarhus (Denmark); Bergstrand, Eva Stabell [Department of Medical Physics, Rikshospital-Radiumhospital Medical Center, Oslo (Norway); Knutsen, Bjoern Helge [Department of Medical Physics, Rikshospital-Radiumhospital Medical Center, Oslo (Norway); Roeislien, Jo [Section of Biostatistics, Rikshospital-Radiumhospital Medical Center, Oslo (Norway); Olsen, Dag Rune [Institute for Cancer Research, Rikshospital-Radiumhospital Medical Center, Oslo (Norway)

    2007-08-21

    The purpose of this study is to investigate whether the method of applicator reconstruction and/or the applicator orientation influence the dose calculation to points around the applicator for brachytherapy of cervical cancer with CT-based treatment planning. A phantom, containing a fixed ring applicator set and six lead pellets representing dose points, was used. The phantom was CT scanned with the ring applicator at four different angles related to the image plane. In each scan the applicator was reconstructed by three methods: (1) direct reconstruction in each image (DR) (2) reconstruction in multiplanar reconstructed images (MPR) and (3) library plans, using pre-defined applicator geometry (LIB). The doses to the lead pellets were calculated. The relative standard deviation (SD) for all reconstruction methods was less than 3.7% in the dose points. The relative SD for the LIB method was significantly lower (p < 0.05) than for the DR and MPR methods for all but two points. All applicator orientations had similar dose calculation reproducibility. Using library plans for applicator reconstruction gives the most reproducible dose calculation. However, with restrictive guidelines for applicator reconstruction the uncertainties for all methods are low compared to other factors influencing the accuracy of brachytherapy.

  19. Dosimetric assessments multi-slice CT of the chest and abdomen in pediatrics; Evaluaciones dosimetricas en TC multicorte de torax y abdomen en pediatria

    Energy Technology Data Exchange (ETDEWEB)

    Giner Sala, M.; Roch Gonzalez, M.; Rodriguez Martin, G.; Garcia Castanon, P.; Espana Lopez, M. L.

    2013-07-01

    The objective of this study is the dosimetry evaluation in pediatric MSCT of thorax and abdomen, and the estimation of effective dose in the different ranges of age taking into account the new ICRP recommendations, by variations that may be involved in explorations that affect breast. (Author)

  20. Clinical application of FDG-PET/CT in metastatic infections

    NARCIS (Netherlands)

    Kouijzer, I.J.E.; Vos, F.J.; Bleeker-Rovers, Chantal P.; Oyen, W.J.G.

    2016-01-01

    FDG-PET/CT has proven its clinical value and cost-effectiveness in diagnosing metastatic infections in patients with Gram-positive bacteremia. In identification of metastatic foci, FDG-PET/CT is useful as a screening method when localizing symptoms are absent because it provides whole-body coverage.

  1. Clinical application of FDG-PET/CT in metastatic infections

    NARCIS (Netherlands)

    Kouijzer, I.J.E.; Vos, F.J.; Bleeker-Rovers, C.P.; Oyen, W.J.G.

    2017-01-01

    FDG-PET/CT has proven its clinical value and cost-effectiveness in diagnosing metastatic infections in patients with Gram-positive bacteremia. In identification of metastatic foci, FDG-PET/CT is useful as a screening method when localizing symptoms are absent because it provides whole-body coverage.

  2. An evaluation on CT image acquisition method for medical VR applications

    Science.gov (United States)

    Jang, Seong-wook; Ko, Junho; Yoo, Yon-sik; Kim, Yoonsang

    2017-02-01

    Recent medical virtual reality (VR) applications to minimize re-operations are being studied for improvements in surgical efficiency and reduction of operation error. The CT image acquisition method considering three-dimensional (3D) modeling for medical VR applications is important, because the realistic model is required for the actual human organ. However, the research for medical VR applications has focused on 3D modeling techniques and utilized 3D models. In addition, research on a CT image acquisition method considering 3D modeling has never been reported. The conventional CT image acquisition method involves scanning a limited area of the lesion for the diagnosis of doctors once or twice. However, the medical VR application is required to acquire the CT image considering patients' various postures and a wider area than the lesion. A wider area than the lesion is required because of the necessary process of comparing bilateral sides for dyskinesia diagnosis of the shoulder, pelvis, and leg. Moreover, patients' various postures are required due to the different effects on the musculoskeletal system. Therefore, in this paper, we perform a comparative experiment on the acquired CT images considering image area (unilateral/bilateral) and patients' postures (neutral/abducted). CT images are acquired from 10 patients for the experiments, and the acquired CT images are evaluated based on the length per pixel and the morphological deviation. Finally, by comparing the experiment results, we evaluate the CT image acquisition method for medical VR applications.

  3. Common breakdown maintenance of GE light speed 16-slice Helical CT%GE light speed 16排螺旋CT常见故障的维修和体会

    Institute of Scientific and Technical Information of China (English)

    苏根元; 王萍萍; 于小晶

    2011-01-01

    Recently,with the extensive application of multi-slice Helical CT,all sorts of failure have been encountered in practice.On the basis of mastering basic principal and structure of multi-slice Helical CT,and relevant knowledge of computer,many breakdowns may be quickly resolved.It has greatly improved the efficiency of equipments and ensured daily operations.This paper briefly describes common breakdown of GE light speed 16-slice Helical CT in our hospital,and summarizes diagnostic analysis,solution and experience.It can serve as reference for concerned personnel.%多排螺旋CT目前已广泛应用于临床,使用过程中会遇到各种各样故障,在熟练掌握多排螺旋CT的基本原理,工作结构,及相关计算机知识的基础上,可以对多排螺旋CT机很多常见故障进行快速及时修复,大大提高了设备使用率,保证临床工作的顺利进行。本文简要阐述了我院GE light speed 16排螺旋CT在使用过程中常见的故障现象、诊断分析、解决方法和体会。为相关专业技术人员提供一定的参考和借鉴。

  4. Finite element modeling of stress distributions and problems for multi-slice longwall mining in Bangladesh, with special reference to the Barapukuria coal mine

    Energy Technology Data Exchange (ETDEWEB)

    Islam, Md. Rafiqul; Hayashi, Daigoro [Simulation Tectonics Laboratory, Department of Physics and Earth Sciences, University of the Ryukyus, Okinawa, 903-0213 (Japan); Kamruzzaman, A.B.M. [Geology Division, Barapukuria Coal Mining Company Limited, Chowhati, Parbatipur, Dinajpur (Bangladesh)

    2009-04-01

    This paper deals with current coal mining operations under a mega-aquifer in NW Bangladesh, and presents a case study of underground mining in Barapukuria. The study uses numerical analyses to evaluate stress redistribution, strata failure, and water inflow enhancements that result from these coal extraction operations. A total of three models (A, B, and C) are presented in this study. Two-dimensional numerical modeling was performed to analyze the deformation and failure behavior of rock elements for two different models (A and B). For model A, we used an elastic finite element software package considering a Mohr-Coulomb failure criterion. For model B, we used boundary element method (BEM). The first two models were applied to determine the stress patterns. Model A provides the tectonic stress pattern of the basin, whereas model B represents the mining-induced stress field. The third model is a schematic model. The results of model A show that tensional failure of rock elements is concentrated in the Gondwana coal sequences as well as within the Eastern Boundary Fault (EBF) and its surroundings. Failure occurs in the middle to lower part of the model, and the magnitude of tensional stress in the shallow part is much greater than in the deeper part. Contours of {tau}{sub max} magnitudes are attributed to up-bending of the overburden, which would create numerous upward propagating fissures/fractures. The results of model B show that fracture propagation would be about 240 m upward for single-slice (height 3 m) mining extraction. From the contours of mean stress magnitudes, it is observed that the high range of fracture propagation increased upward for multi-slice extraction of coal. It is apparent from the fracture heights that large amounts of caving would occur towards the roof due to the multi-slice extraction of coal, and finally would be linked with the water-bearing Dupi Tila Formation. If this happened, it would ultimately cause a major water inflow hazard in

  5. New Applications of Cardiac Computed Tomography Dual-Energy, Spectral, and Molecular CT Imaging

    NARCIS (Netherlands)

    Danad, Ibrahim; Fayad, Zahi A.; Willemink, Martin J.; Min, James K.

    2015-01-01

    Computed tomography (CT) has evolved into a powerful diagnostic tool, and it is impossible to imagine current clinical practice without CT imaging. Because of its widespread availability, ease of clinical application, superb sensitivity for the detection of coronary artery disease, and noninvasive n

  6. Comparison of lung scintigraphy with multi-slice spiral computed tomography in the diagnosis of pulmonary embolism.

    Science.gov (United States)

    Wang, Feng; Fang, Wei; Lv, Bin; Lu, Jin-Guo; Xiong, Chang-Ming; Ni, Xin-Hai; He, Zuo-Xiang

    2009-07-01

    To compare the diagnostic efficacy of lung perfusion scans combined with ventilation (V/Q) scans and/or chest radiography (CR) with contrast-enhanced multislice spiral CT pulmonary angiography (CTPA) in diagnosing pulmonary embolism (PE). Eighty-two consecutive patients with suspected PE underwent CTPA, lung perfusion scan, and CR. Of them, 28 patients underwent V/Q scans. The final diagnosis was made using a composite reference test. The overall sensitivity and specificity were 89.2% and 92.1% for V/Q scan or perfusion scan combined with CR, and 97.3% and 97.4% for CTPA. For the 28 patients with V/Q scan, the sensitivity and specificity were 91.7% and 92.9% for V/Q scan, and 91.7% and 100.0% for CTPA. The segmental agreement rate between perfusion scan and CTPA was 69.5% (kappa = 0.30, P < 0.05). The perfusion scan revealed significantly more subsegmental abnormalities than CTPA (59 vs. 10, chi2 test, P < 0.05). V/Q scan, perfusion scan combined with CR and CTPA all show high efficacy in diagnosing PE. V/Q scan or perfusion scan combined with CR is as accurate as CTPA.

  7. 多层螺旋CT血管成像容积重建技术在Moyamoya病中的诊断价值%The diagnostic value of multi-slice computed tomographic angiography with volume rendering for Moyamoya disease

    Institute of Scientific and Technical Information of China (English)

    林伯法; 奚玉平; 曹国全

    2008-01-01

    Objective To evaluate the diagnostic value of multi-slice thrce-dimensional computed tomographic angiography(MS-CTA) with volume rendering(VR) for Moyamoya disease.Methods MS-CTA of 25 patients with Moyamoya disease verified by DSA were restrospectively analyzed.Source images were got by GE Lightspeed pro scanner.VR was adopted to reconstruct 3D images in all cases.Results Of 25 CT precontrast,13,12 cases showed infarction and hemorrhage respectively,while 11 cases had dialated vessels in thalamus-basal ganglia region on CT.Accuracy of stenosis or occlusion of the bifurcation of ICA, proximal portion of the ACA or MCA was 88.0% (22/25) by MS-CTA.MS-CTA overestimated the degree of stenosis,MS-CTA misdiagnosed 3 cases(12.0%)with stenosis to occlusion.MS-CTA showed fewer small Moyamoya vessels than DSA.MS-CTA only demonstrated 6 cases(25.0%)with collateral vessels.Conclusion CT is still the conventional method for detecting secondary lesions to Moyamoya disease.CT and MS-CTA can accurately diagnose Moyamoya disease.%目的 探讨多层螺旋CT血管造影(MS-CTA)容积重建(VR)技术在Moyamoya病中的诊断价值.方法 对经DSA证实的25例Moyamoya患者的MS-CTA影像资料进行回顾性分析,使用GE Lightspeed pro 16层螺旋CT扫描仪获得原始图像,所有病例均采用VR技术对图像进行三维重建.结果 25例CT平扫患者中,脑梗死13例,脑出血12例,其中11例可见丘脑一基底节区有扩张的血管;MS-CTA VR重建显示Moyamoya病颈内动脉(ICA)末端、大脑中动脉(MCA)或大脑前动脉(ACA)近端闭塞或狭窄的准确率为88.0%(22/25).与DSA相比,MS-CTA VR重建高估动脉狭窄程度,将ICA狭窄误诊为闭塞3例(12.0%);在显示Moyamoya血管数目及分支方面,MS-CTA VR重建显示细小分支数目较少;在显示侧支循环方面,MS-CTA VR重建仅显示6例(25.0%).结论 CT平扫仍是发现Moyamoya病继发病变的常规方法,与MS-CTA VR重建相结合可正确诊断Moyamoya病.

  8. Clinical application of flat-panel CT in the angio suite; Klinische Anwendung der Flachdetektor-CT im Angio-OP

    Energy Technology Data Exchange (ETDEWEB)

    Hausegger, K.A.; Fuerstner, M.; Hauser, M.; Smetana, F.; Kau, T. [Landeskrankenhaus Klagenfurt (Austria). Roentgendiagnostisches Zentralinstitut; Klinikum Klagenfurt (Austria). Inst. fuer Diagnostische und Interventionelle Radiologie

    2011-12-15

    The introduction of flat-panel detectors in modern angiographic C-arm systems makes it possible to acquire CT-like images in the angiographic suite (flat-panel CT; FD-CT). In this review, after a short technical introduction of FD-CT including the discussion of the advantages and disadvantages of this new imaging modality, the most commonly and best evaluated indications for FD-CT will be described. FD-CT has become an important adjunctive imaging modality in neurointerventional procedures and embolizations, especially during liver embolization. Another attractive indication for FD-CT is musculoskeletal interventions. FD-CT may provide important additional information in complicated peripheral vascular interventions and stent-graft procedures. FD-CT has a broad spectrum of possible applications, which finally depends on the experience and innovative thinking of the operator. However, it has to be kept in mind that FD-CT causes additional radiation exposure. Roughly, it can be assumed that currently one FD-CT sequence causes at least the same radiation exposure as one spiral CT sequence of the corresponding body region. (orig.)

  9. Effect of heart rate on CT angiography using the enhanced cardiac model of the 4D NCAT

    Science.gov (United States)

    Segars, W. P.; Taguchi, K.; Fung, G. S. K.; Fishman, E. K.; Tsui, B. M. W.

    2006-03-01

    We investigate the effect of heart rate on the quality and artifact generation in coronary artery images obtained using multi-slice computed tomography (MSCT) with the purpose of finding the optimal time resolution for data acquisition. To perform the study, we used the 4D NCAT phantom, a computer model of the normal human anatomy and cardiac and respiratory motions developed in our laboratory. Although capable of being far more realistic, the 4D NCAT cardiac model was originally designed for low-resolution imaging research, and lacked the anatomical detail to be applicable to high-resolution CT. In this work, we updated the cardiac model to include a more detailed anatomy and physiology based on high-resolution clinical gated MSCT data. To demonstrate its utility in high-resolution dynamic CT imaging research, the enhanced 4D NCAT was then used in a pilot simulation study to investigate the effect of heart rate on CT angiography. The 4D NCAT was used to simulate patients with different heart rates (60-120 beats/minute) and with various cardiac plaques of known size and location within the coronary arteries. For each simulated patient, MSCT projection data was generated with data acquisition windows ranging from 100 to 250 ms centered within the quiet phase (mid-diastole) of the heart using an analytical CT projection algorithm. CT images were reconstructed from the projection data, and the contrast of the plaques was then measured to assess the effect of heart rate and to determine the optimal time resolution required for each case. The 4D NCAT phantom with its realistic model for the cardiac motion was found to provide a valuable tool from which to optimize CT cardiac applications. Our results indicate the importance of optimizing the time resolution with regard to heart rate and plaque location for improved CT images at a reduced patient dose.

  10. 胃间质瘤MSCT诊断及临床应用价值%Diagnosis and clinical value of multi-slice spiral computed tomography in gastrointestinal stromal tumor

    Institute of Scientific and Technical Information of China (English)

    李小龙; 杨铁; 王巍; 卓家驹; 刘刚; 吴坚

    2013-01-01

    Objective To discuss the diagnostic value and clinical application value of multi-slice spiral computed tomography about gastrointestinal stromal tumor.Methods We analyze 38 cases with stomach stromal tumor which are confirmed by pathology and immunohistochemistry retrospectively,observe the size,shape,density,reinforcement of lesion or focus and other organ invaded and secondary changes,and decide that it is benign tumor or malignant tumor.Results The maximum diameter of tumor is smaller than 5 cm (4 cases),the maximum diameter of tumor is from 5 cm to 10 cm (22 cases),the maximum diameter of tumor is bigger than 10 cm (12 cases).There is necrosis and cystic change (13 cases) and hemorrhage (8 cases) in the lesion.The normal membrana mucosa is not existed in the gastral cavity (10 cases).The focus is communicated with gastral cavity because of ulcer formation (8 cases) but there is not any ulcer of stomach although air is in gastral cavity (2 cases).It is asymmetry reinforcement of the tumor and the center of the focus is without any reinforcement sometime.The tumor has adhesion to tissue or organ around it (28 cases).The preoperative diagnoses are benign tumor (5 cases),anaplastic tumor or borderline tumors (23 cases),malignant tumor (10 cases) according to size,density and contiguity.Conclusion It is possible to display stomach stromal tumor focus by multi-slice spiral computed tomography definitely and to supply effective information about diagnosis and grading.Image of multi-slice spiral computed tomography is effective measure about preoperative evaluation and postoperative follow-up and curative effect assessment to stomach stromal tumor.It is effective supplement of endoscopy.%目的 探讨多层螺旋CT对胃间质瘤的诊断价值及临床应用价值.方法 回顾性分析经手术病理学及免疫组织化学证实的胃间质瘤患者38例,观察其病灶大小、形态、密度、病灶强化特点、肿瘤累及范围以及其他继发改变

  11. Quantitative multi-slice computed tomography assessment of the mitral valvular complex for transcatheter mitral valve interventions part 1: systematic measurement methodology and inter-observer variability.

    Science.gov (United States)

    Thériault-Lauzier, Pascal; Mylotte, Darren; Dorfmeister, Magdalena; Spaziano, Marco; Andalib, Ali; Mamane, Samuel; Chetrit, Michael; Blanke, Philipp; Cecere, Renzo; Buithieu, Jean; Martucci, Giuseppe; Tchetche, Didier; Modine, Thomas; van Mieghem, Nicolas; Lange, Rüdiger; Windecker, Stephan; Bilodeau, Luc; Leipsic, Jonathon; Piazza, Nicolo

    2016-10-10

    Transcatheter mitral valve replacement (TMVR) is an emerging technology with the potential to treat patients with severe mitral regurgitation at excessive risk for surgical mitral valve surgery. Multimodality imaging of the mitral valvular complex and surrounding structures will be an important component for patient selection for TMVR. Our aim was to describe and evaluate a systematic multi-slice computed tomography (MSCT) image analysis methodology that provides measurements relevant for transcatheter mitral valve replacement. A systematic step-by-step measurement methodology is described for structures of the mitral valvular complex including: the mitral valve annulus, left ventricle, left atrium, papillary muscles and left ventricular outflow tract. To evaluate reproducibility, two observers applied this methodology to a retrospective series of 49 cardiac MSCT scans in patients with heart failure and significant mitral regurgitation. For each of 25 geometrical metrics, we evaluated inter-observer difference and intra-class correlation. The inter-observer difference was below 10% and the intra-class correlation was above 0.81 for measurements of critical importance in the sizing of TMVR devices: the mitral valve annulus diameters, area, perimeter, the inter-trigone distance, and the aorto-mitral angle. MSCT can provide measurements that are important for patient selection and sizing of TMVR devices. These measurements have excellent inter-observer reproducibility in patients with functional mitral regurgitation.

  12. Physical dose distribution due to multi-sliced kV X-ray beam in labeled tissue-like media: An experimental approach

    Energy Technology Data Exchange (ETDEWEB)

    Ghasemi, M., E-mail: mghasemi@nrcam.or [Agricultural Medical and Industrial Research School, NSTRI, P.O. Box 31485-498, Karaj (Iran, Islamic Republic of); Kakuee, O.R.; Fathollahi, V. [Van de Graaff Laboratory, Nuclear Science Research School, NSTRI, P.O. Box 14395-836, Tehran (Iran, Islamic Republic of); Shahvar, A.; Mohati, M.; Ghafoori, M. [Agricultural Medical and Industrial Research School, NSTRI, P.O. Box 31485-498, Karaj (Iran, Islamic Republic of)

    2011-02-15

    Radiotherapy remains a major modality of cancer therapy. Thanks to high flux and high brilliance of synchrotron-generated X-ray, laboratory research with planar microscopically thin X-ray beam promise exciting new opportunities for treatment of cancer. High tolerance of normal tissues at doses up to several hundred Gy in a single dose fraction and preferential damage of tumors at very high doses have been uniquely observed in animal models exposed to microbeams. The fact that beams as thick as 0.68 mm could retain a part of these effects, opens the possibility that the required beam can be produced by high power X-ray tubes besides a dedicated synchrotron. Fortunately, dose distribution due to kilovolt X-rays could be enhanced by the introduction of high-Z contrast agents to tissue-like media. In this work, dose deposition in a phantom-partially loaded with Au and I as contrast agents-irradiated by multi-sliced kV X-ray beam was experimentally investigated in the peak and valley regions both on the surface and in the depth of phantom. The results of experimental dosimetry using Gaf-chromic films were compared with corresponding Monte-Carlo simulation. Relative reduction in the deposited dose in the peak regions downstream the area containing contrast agents in comparison with the adjacent areas was experimentally observed.

  13. Physical dose distribution due to multi-sliced kV X-ray beam in labeled tissue-like media: an experimental approach.

    Science.gov (United States)

    Ghasemi, M; Kakuee, O R; Fathollahi, V; Shahvar, A; Mohati, M; Ghafoori, M

    2011-02-01

    Radiotherapy remains a major modality of cancer therapy. Thanks to high flux and high brilliance of synchrotron-generated X-ray, laboratory research with planar microscopically thin X-ray beam promise exciting new opportunities for treatment of cancer. High tolerance of normal tissues at doses up to several hundred Gy in a single dose fraction and preferential damage of tumors at very high doses have been uniquely observed in animal models exposed to microbeams. The fact that beams as thick as 0.68 mm could retain a part of these effects, opens the possibility that the required beam can be produced by high power X-ray tubes besides a dedicated synchrotron. Fortunately, dose distribution due to kilovolt X-rays could be enhanced by the introduction of high-Z contrast agents to tissue-like media. In this work, dose deposition in a phantom--partially loaded with Au and I as contrast agents--irradiated by multi-sliced kV X-ray beam was experimentally investigated in the peak and valley regions both on the surface and in the depth of phantom. The results of experimental dosimetry using Gaf-chromic films were compared with corresponding Monte-Carlo simulation. Relative reduction in the deposited dose in the peak regions downstream the area containing contrast agents in comparison with the adjacent areas was experimentally observed.

  14. Rapid assessment of myocardial infarct size in rodents using multi-slice inversion recovery late gadolinium enhancement CMR at 9.4T

    Directory of Open Access Journals (Sweden)

    Hausenloy Derek J

    2011-09-01

    Full Text Available Abstract Background Myocardial infarction (MI can be readily assessed using late gadolinium enhancement (LGE cardiovascular magnetic resonance (CMR. Inversion recovery (IR sequences provide the highest contrast between enhanced infarct areas and healthy myocardium. Applying such methods to small animals is challenging due to rapid respiratory and cardiac rates relative to T1 relaxation. Methods Here we present a fast and robust protocol for assessing LGE in small animals using a multi-slice IR gradient echo sequence for efficient assessment of LGE. An additional Look-Locker sequence was used to assess the optimum inversion point on an individual basis and to determine most appropriate gating points for both rat and mouse. The technique was applied to two preclinical scenarios: i an acute (2 hour reperfused model of MI in rats and ii mice 2 days following non-reperfused MI. Results LGE images from all animals revealed clear areas of enhancement allowing for easy volume segmentation. Typical inversion times required to null healthy myocardium in rats were between 300-450 ms equivalent to 2-3 R-waves and ~330 ms in mice, typically 3 R-waves following inversion. Data from rats was also validated against triphenyltetrazolium chloride staining and revealed close agreement for infarct size. Conclusion The LGE protocol presented provides a reliable method for acquiring images of high contrast and quality without excessive scan times, enabling higher throughput in experimental studies requiring reliable assessment of MI.

  15. Computer-aided diagnosis for osteoporosis using chest 3D CT images

    Science.gov (United States)

    Yoneda, K.; Matsuhiro, M.; Suzuki, H.; Kawata, Y.; Niki, N.; Nakano, Y.; Ohmatsu, H.; Kusumoto, M.; Tsuchida, T.; Eguchi, K.; Kaneko, M.

    2016-03-01

    The patients of osteoporosis comprised of about 13 million people in Japan and it is one of the problems the aging society has. In order to prevent the osteoporosis, it is necessary to do early detection and treatment. Multi-slice CT technology has been improving the three dimensional (3-D) image analysis with higher body axis resolution and shorter scan time. The 3-D image analysis using multi-slice CT images of thoracic vertebra can be used as a support to diagnose osteoporosis and at the same time can be used for lung cancer diagnosis which may lead to early detection. We develop automatic extraction and partitioning algorithm for spinal column by analyzing vertebral body structure, and the analysis algorithm of the vertebral body using shape analysis and a bone density measurement for the diagnosis of osteoporosis. Osteoporosis diagnosis support system obtained high extraction rate of the thoracic vertebral in both normal and low doses.

  16. Motion estimation and compensation in dynamic spiral CT reconstruction; Estimation et compensation de mouvement en reconstruction dynamique de tomodensitometrie helicoidale

    Energy Technology Data Exchange (ETDEWEB)

    Kimdon, J.; Grangeat, P.; Koenig, A.; Bonnet, St

    2004-07-01

    Respiratory and cardiac motion causes blurring in dynamic X-ray Computed Tomography (CT). Fast scans reduce this problem, but they require a higher radiation dose per time period to maintain the signal to noise ratio of the resulting images, thereby magnifying the health risk to the patient. As an alternative to increased radiation, our team has already developed a cone-beam reconstruction algorithm based on a dynamic particle model that estimates, predicts, and compensates for respiratory motion in circular X-ray CT. The current paper presents an extension of this method to spiral CT, applicable to modern multi-slice scanners that take advantage of the speed and dose benefits of helical trajectories. We adapted all three main areas of the algorithm: backprojection, prediction, and compensation/accumulation. In backprojection, we changed the longitudinal re-binning technique, filter direction, and the method of enforcing the data sufficiency requirements. For prediction, we had to be careful of objects appearing and disappearing as the scanner bed advanced. For compensation/accumulation, we controlled the reconstruction time and combined images to cover a greater longitudinal extent for each phase in the respiratory or cardiac cycle. Tests with moving numerical phantoms demonstrate that the algorithm successfully improves the temporal resolution of the images without increasing the dose or reducing the signal-to-noise ratio. (authors)

  17. Motion estimation and compensation in dynamic spiral CT reconstruction; Estimation et compensation de mouvement en reconstruction dynamique de tomodensitometrie helicoidale

    Energy Technology Data Exchange (ETDEWEB)

    Kimdon, J.; Grangeat, P.; Koenig, A.; Bonnet, St

    2004-07-01

    Respiratory and cardiac motion causes blurring in dynamic X-ray Computed Tomography (CT). Fast scans reduce this problem, but they require a higher radiation dose per time period to maintain the signal to noise ratio of the resulting images, thereby magnifying the health risk to the patient. As an alternative to increased radiation, our team has already developed a cone-beam reconstruction algorithm based on a dynamic particle model that estimates, predicts, and compensates for respiratory motion in circular X-ray CT. The current paper presents an extension of this method to spiral CT, applicable to modern multi-slice scanners that take advantage of the speed and dose benefits of helical trajectories. We adapted all three main areas of the algorithm: backprojection, prediction, and compensation/accumulation. In backprojection, we changed the longitudinal re-binning technique, filter direction, and the method of enforcing the data sufficiency requirements. For prediction, we had to be careful of objects appearing and disappearing as the scanner bed advanced. For compensation/accumulation, we controlled the reconstruction time and combined images to cover a greater longitudinal extent for each phase in the respiratory or cardiac cycle. Tests with moving numerical phantoms demonstrate that the algorithm successfully improves the temporal resolution of the images without increasing the dose or reducing the signal-to-noise ratio. (authors)

  18. Radiation dose in cerebral angiography and flat detector CT applications in neuroradiology; Strahlendosis bei zerebraler Angiographie und Flachdetektor-CT-Applikationen in der Neuroradiologie

    Energy Technology Data Exchange (ETDEWEB)

    Struffert, T.; Lang, S.; Doerfler, A. [Universitaetsklinikum Erlangen, Friedrich-Alexander-Universitaet Erlangen-Nuernberg, Abteilung fuer Neuroradiologie, Erlangen (Germany); Scholz, R. [Siemens Healthcare GmbH, Forchheim (Germany); Hauer, M. [Klinikum Nuernberg Sued, Institut fuer Radiologie und Neuroradiologie, Nuernberg (Germany)

    2015-08-15

    Flat detectors (FD) have completely replaced image intensifiers in angiography. Due to this development not only the image quality of 2D digital subtraction angiography series (2-D-DSA) could be improved but also the acquisition of computed tomography (CT)-like cross-sectional images (FD-CT) within the angio suite became feasible. These techniques are now being used in daily clinical routine. Only little information about effective doses of these applications to patients has been published in the literature. We describe the effective patient dose of current applications in the field of angiography and demonstrate strategies to minimize the dose to the patient. In addition, we compare FD-CT applications to standard multislice CT applications. (orig.) [German] Flachdetektoren haben Bildverstaerker in der Angiographie vollstaendig abgeloest. Mit dieser Entwicklung verbesserte sich nicht nur die Bildqualitaet subtrahierter 2-D-Angiographieserien (2-D-DSA), sondern auch die Akquisition CT-aehnlicher Schnittbilder (FD-CT) mit unterschiedlichen Indikationen wurde moeglich. Diese Techniken werden nun in der taeglichen klinischen Routine eingesetzt. Angaben zur effektiven Patientendosis dieser Applikationen sind bis jetzt in der Literatur nur wenige publiziert worden. Wir beschreiben die effektive Patientendosis aktueller Anwendungen im Bereich der Angiographie und zeigen Strategien zur Minimierung der Dosis fuer den Patienten auf. Zudem vergleichen wir FD-CT-Applikationen mit Standard-Multislice-CT-Anwendungen. (orig.)

  19. Application of dual-energy X-ray in vascular calcification in patients with chronic kidney disease%双能X线在慢性肾脏病患者血管钙化中的应用

    Institute of Scientific and Technical Information of China (English)

    吴晓婵; 罗福漳; 洪国保

    2015-01-01

    目的:探讨双能X线骨密度检测在慢性肾脏病(CKD)患者血管钙化诊断中的应用价值。方法选取2013年1月~2014年12月本院接诊的42例CKD 3~5期患者作为研究对象,所有患者均行双能X线检查。以多层螺旋CT诊断为金标准,评价双能X线检测在CKD 3~5期患者血管钙化诊断中的敏感度和特异性。结果多层螺旋 CT在 CKD 3期、CKD 4期、CKD 5期的检出率分别为33.3%、52.2%、100.0%,双能X线的检出率分别为22.2%、43.5%、90.0%,且多层螺旋CT的总检出率为59.5%,与双能X线检测的50.0%比较,差异无统计学意义(P跃0.05)。以多层螺旋CT检测为金标准,双能X线检测的特异性为100.0%,敏感度为84.0%。结论双能X线可应用于检测CKD 3~5期患者的血管钙化,具有较好的临床价值。%Objective To exolore the application value of dual-energy X-ray in the detection of vascular calcification in chronic kidney disease (CKD) patients. Methods 42 cases of CKD 3-5 stages from January 2013 to December 2014 in our hospital were selected as the research objects.All patients were given dual-energy X-ray examination.The sensi-tivity and specificity of dual-energy X-ray examination in the diagnosis of vascular calcification in patients with CKD 3-5 stages were evaluated by using the gold standard of the diagnosis of multi-slice spiral CT. Results The detection rate in CKD 3-5 stages by multi-slice spiral CT was 33.3%,52.2%,100.0% respectively,while the detection rate in CKD 3-5 stages by dual-energy X-ray was 22.2%,43.5%,90.0% respectively.The total detection rate of multi-slice spiral CT was 59.5%,the otal detection rate of multi-slice spiral CT was 50.0%,there was no significant difference (P>0.05).The specificity of dual energy X-ray detection was 84%,and the sensitivity was 100%,with the detection of multi slice spiral CT as gold standard. Conclusion Dual-energy X-ray can be used in the detection of vascular calcification in chronic

  20. Simultaneous multi-slice Turbo-FLASH imaging with CAIPIRINHA for whole brain distortion-free pseudo-continuous arterial spin labeling at 3 and 7 T.

    Science.gov (United States)

    Wang, Yi; Moeller, Steen; Li, Xiufeng; Vu, An T; Krasileva, Kate; Ugurbil, Kamil; Yacoub, Essa; Wang, Danny J J

    2015-06-01

    Simultaneous multi-slice (SMS) or multiband (MB) imaging has recently been attempted for arterial spin labeled (ASL) perfusion MRI in conjunction with echo-planar imaging (EPI) readout. It was found that SMS-EPI can reduce the T1 relaxation effect of the label and improve image coverage and resolution with little penalty in signal-to-noise ratio (SNR). However, EPI still suffers from geometric distortion and signal dropout from field inhomogeneity effects especially at high and ultrahigh magnetic fields. Here we present a novel scheme for achieving high fidelity distortion-free quantitative perfusion imaging by combining pseudo-continuous ASL (pCASL) with SMS Turbo-FLASH (TFL) readout at both 3 and 7 T. Bloch equation simulation was performed to characterize and optimize the TFL-based pCASL perfusion signal. Two MB factors (3 and 5) were implemented in SMS-TFL pCASL and compared with standard 2D TFL and EPI pCASL sequences. The temporal SNR of SMS-TFL pCASL relative to that of standard TFL pCASL was 0.76 ± 0.10 and 0.74 ± 0.11 at 7 T and 0.70 ± 0.05 and 0.65 ± 0.05 at 3T for MB factor of 3 and 5, respectively. By implementing background suppression in conjunction with SMS-TFL at 3T, the relative temporal SNR improved to 0.84 ± 0.09 and 0.79 ± 0.10 for MB factor of 3 and 5, respectively. Compared to EPI pCASL, significantly increased temporal SNR (pbrain distortion-free quantitative mapping of cerebral blood flow at high and ultrahigh magnetic fields.

  1. Accelerated magnetic resonance diffusion tensor imaging of the median nerve using simultaneous multi-slice echo planar imaging with blipped CAIPIRINHA

    Energy Technology Data Exchange (ETDEWEB)

    Filli, Lukas; Kenkel, David; Boss, Andreas; Manoliu, Andrei; Andreisek, Gustav; Runge, Val M.; Guggenberger, Roman [University Hospital of Zurich, University of Zurich, Institute of Diagnostic and Interventional Radiology, Zurich (Switzerland); Piccirelli, Marco [University Hospital of Zurich, Department of Neuroradiology, Zurich (Switzerland); Bhat, Himanshu [Siemens Medical Solutions USA Inc, Charlestown, MA (United States)

    2016-06-15

    To investigate the feasibility of MR diffusion tensor imaging (DTI) of the median nerve using simultaneous multi-slice echo planar imaging (EPI) with blipped CAIPIRINHA. After federal ethics board approval, MR imaging of the median nerves of eight healthy volunteers (mean age, 29.4 years; range, 25-32) was performed at 3 T using a 16-channel hand/wrist coil. An EPI sequence (b-value, 1,000 s/mm{sup 2}; 20 gradient directions) was acquired without acceleration as well as with twofold and threefold slice acceleration. Fractional anisotropy (FA), mean diffusivity (MD) and quality of nerve tractography (number of tracks, average track length, track homogeneity, anatomical accuracy) were compared between the acquisitions using multivariate ANOVA and the Kruskal-Wallis test. Acquisition time was 6:08 min for standard DTI, 3:38 min for twofold and 2:31 min for threefold acceleration. No differences were found regarding FA (standard DTI: 0.620 ± 0.058; twofold acceleration: 0.642 ± 0.058; threefold acceleration: 0.644 ± 0.061; p ≥ 0.217) and MD (standard DTI: 1.076 ± 0.080 mm{sup 2}/s; twofold acceleration: 1.016 ± 0.123 mm{sup 2}/s; threefold acceleration: 0.979 ± 0.153 mm{sup 2}/s; p ≥ 0.074). Twofold acceleration yielded similar tractography quality compared to standard DTI (p > 0.05). With threefold acceleration, however, average track length and track homogeneity decreased (p = 0.004-0.021). Accelerated DTI of the median nerve is feasible. Twofold acceleration yields similar results to standard DTI. (orig.)

  2. Automated multi-slice extracellular and patch-clamp experiments using the WinLTP data acquisition system with automated perfusion control

    Science.gov (United States)

    Anderson, William W.; Fitzjohn, Stephen M.; Collingridge, Graham L.

    2012-01-01

    WinLTP is a data acquisition program for studying long-term potentiation (LTP) and other aspects of synaptic function. Earlier versions of WinLTP (J. Neurosci. Methods, 162:346–356, 2007) provided automated electrical stimulation and data acquisition capable of running nearly an entire synaptic plasticity experiment, with the primary exception that perfusion solutions had to be changed manually. This automated stimulation and acquisition was done by using ‘Sweep’, ‘Loop’ and ‘Delay’ events to build scripts using the ‘Protocol Builder’. However, this did not allow automatic changing of many solutions while running multiple slice experiments, or solution changing when this had to be performed rapidly and with accurate timing during patch-clamp experiments. We report here the addition of automated perfusion control to WinLTP. First, perfusion change between sweeps is enabled by adding the ‘Perfuse’ event to Protocol Builder scripting and is used in slice experiments. Second, fast perfusion changes during as well as between sweeps is enabled by using the Perfuse event in the protocol scripts to control changes between sweeps, and also by changing digital or analog output during a sweep and is used for single cell single-line perfusion patch-clamp experiments. The addition of stepper control of tube placement allows dual- or triple-line perfusion patch-clamp experiments for up to 48 solutions. The ability to automate perfusion changes and fully integrate them with the already automated stimulation and data acquisition goes a long way toward complete automation of multi-slice extracellularly recorded and single cell patch-clamp experiments. PMID:22524994

  3. Genetic association of glutathione peroxidase-1 with coronary artery calcification in type 2 diabetes: a case control study with multi-slice computed tomography

    Directory of Open Access Journals (Sweden)

    Fujimoto Kei

    2007-09-01

    Full Text Available Abstract Background Although oxidative stress by accumulation of reactive oxygen species (ROS in diabetes has become evident, it remains unclear what genes, involved in redox balance, would determine susceptibility for development of atherosclerosis in diabetes. This study evaluated the effect of genetic polymorphism of enzymes producing or responsible for reducing ROS on coronary artery calcification in type 2 diabetes (T2D. Methods An index for coronary-arteriosclerosis, coronary artery calcium score (CACS was evaluated in 91 T2D patients using a multi-slice computed tomography. Patients were genotyped for ROS-scavenging enzymes, Glutathione peroxidase-1 (GPx-1, Catalase, Mn-SOD, Cu/Zn-SOD, as well as SNPs of NADPH oxidase as ROS-promoting elements, genes related to onset of T2D (CAPN10, ADRB3, PPAR gamma, FATP4. Age, blood pressure, BMI, HbA1c, lipid and duration of diabetes were evaluated for a multivariate regression analysis. Results CACS with Pro/Leu genotype of the GPx-1 gene was significantly higher than in those with Pro/Pro (744 ± 1,291 vs. 245 ± 399, respectively, p = 0.006. In addition, genotype frequency of Pro/Leu in those with CACS ≥ 1000 was significantly higher than in those with CACS OR = 3.61, CI = 0.97–13.42; p = 0.045 when tested for deviation from Hardy-Weinberg's equilibrium. Multivariate regression analyses revealed that CACS significantly correlated with GPx-1 genotypes and age. Conclusion The presence of Pro197Leu substitution of the GPx-1 gene may play a crucial role in determining genetic susceptibility to coronary-arteriosclerosis in T2D. The mechanism may be associated with a decreased ability to scavenge ROS with the variant GPx-1.

  4. The evaluation of anti-angiogenic treatment effects for implanted rabbit VX2 breast tumors using functional multi-slice spiral computed tomography (f-MSCT)

    Energy Technology Data Exchange (ETDEWEB)

    Lei Zhen, E-mail: leizhen2004@163.com [Department of Anatomy, Chinese Medical University, No. 92, Beiermalu Road, Heping District, Shenyang, 110001 (China) and Department of Radiology, The First Hospital of Liaoning Medical College, No. 2, Wuduan, Renmin Street, Jinzhou, 121001 (China); Ma Heji, E-mail: maheji9831@sina.com [Department of Radiology, The First Hospital of Liaoning Medical College, No. 2, Wuduan, Renmin Street, Jinzhou, 121001 (China); Xu Na, E-mail: xuna821230@sohu.com [Department of Radiology, The First Hospital of Liaoning Medical College, No. 2, Wuduan, Renmin Street, Jinzhou, 121001 (China); Xi Huanjiu, E-mail: xihuanjiu2004@yahoo.cn [Anthropology Institute, Liaoning Medical College, No. 40, Sanduan, Songpo Rd, Jinzhou, 121001 (China)

    2011-05-15

    Objective: Investigate the benefit of functional multi-slice spiral computed tomography (f-MSCT) perfusion imaging in the non-invasive assessment of targeted anti-angiogenesis therapy on an implanted rabbit VX2 breast tumor model. Method: 69 female pure New Zealand white rabbits were randomly assigned to one of the 4 groups and received treatment accordingly: control (saline), Endostar, neoadjuvant chemotherapy (Cyclophosphamide, Epirubicin and 5-Fluorouracil, CEF), combination therapy (Endostar and CEF). After 2 weeks of treatment, f-MSCT perfusion scannings were performed for all rabbits and information about blood flow (BF), blood volume (BV), mean transit time (MTT) and surface permeability (SP) was collected. After perfusion imaging, tumor tissues were sampled for immunohistochemistry and the Western blot test of VEGF protein expression. Results: (1) The VEGF expression level, measured by immunohistochemistry and Western blot, decreased by treatment group (control > Endostar > CEF > combination therapy). The same was true for the mean BF, BV, MTT and PS, which decreased from the control group to the combination therapy group gradually. The mean MTT level increased in reverse order from the control to the combination therapy group. The difference between any 2 groups on these measures was statistically significant (P < 0.05). (2) There was moderate positive correlation between VEGF expression and BE, BV, or PS level (P < 0.05) and a negative correlation between VEGF expression and MTT level for all 4 groups (P < 0.05). Conclusion: Therefore, f-MSCT can be used as a non-invasive approach to evaluate the effect of anti-angiogenic therapy for implanted rabbit VX2 breast tumors.

  5. 多层CT小肠造影与单气囊小肠镜对小肠梗阻的诊断价值%Diagnostic value of multi-slice computed tomography enterography before single balloon enteroscopy for small bowel obstruction

    Institute of Scientific and Technical Information of China (English)

    李娜; 赵晓军; 王海红; 王昕; 李爱琴; 谢惠; 余东亮; 韩英; 盛剑秋

    2013-01-01

    目的 探讨多层CT小肠造影(MSCTE)与单气囊小肠镜(SBE)在小肠梗阻性病变的诊断价值.方法 收集2009年6月-2013年2月临床和/或腹部X线平片疑为小肠梗阻的患者30例.所有患者先行MSCTE检查,根据检查结果选择经口或经肛SBE检查.分析两种检查方法对小肠梗阻性病变的诊断率.结果 ①MSCTE检查诊断小肠梗阻的灵敏度为85.19%,特异度为66.67%,阳性预测值为95.83%,阴性预测值为33.33%.SBE检查分别为81.48%、100%、100%和37.50%.②MSCTE和SBE检出病变一致性为53.33% (16/30).③根据MSCTE检查结果选择经口或经肛SBE检查,MSCTE检查阳性指导SBE选择进镜方式正确率高于MSCTE检查阴性(95.83% vs 33.33%,P<0.05).结论 MSCTE和SBE对小肠梗阻的诊断率相当,二者联合应用可提高对小肠梗阻性病变的诊断率.MSCTE检查结果可以指导SBE选择进镜方式.%Objective To evaluate the diagnostic value of multi-slice CT enterography (MSCTE) before single balloon enteroscopy (SBE) for patients with small bowel obstruction (SBO).Methods 30 patients with MSCTE before SBE for SBO were collected prospectively from Jun.2009 to Feb.2013.The clinical impact of MSCTE on the subsequent SBE examinations and the diagnostic yields of both MSCTE and SBE were evaluated respectively.Results ① In detecting SBO,MSCTE had a sensitivity of 85.19%,a specificity of 66.67%,a positive predictive value of 95.83%,and a negative predictive value of 33.33%.SBE had a sensitivity of 81.48%,a specificity of 100%,a positive predictive value of 100%,and a negative predictive value of 37.5%.② The consistency was 53.33%.③ The choice of initial route of SBE was correct in those with a positive MSCTE vs negative MSCTE (95.83% vs 33.33 %,P <0.05).Conclusion MSCTE and SBE are nearly equal in their ability to detect SBO.The combined application of two methods can improve the diagnosis rate of SBO.This study suggests MSCTE

  6. Application of CT 3D reconstruction in diagnosing atlantoaxial subluxation

    Institute of Scientific and Technical Information of China (English)

    段少银; 林清池; 庞瑞麟

    2004-01-01

    Objective:To evaluate and compare the diagnostic value in atlantoaxial subluxation by CT three-dimensional (3D) reconstruction.Methods:3D reconstruction fimdings of 41 patients with atlantoaxiai subluxation were retrospectively analyzed, and comparisons were made among images of transverse section, multiplanar reformorting (MPR), surface shade display (SSD), maximum intensity project (MIP), and volume rendering (VR). Results:Of 41 patients with atlantoaxial subluxation, 31 belonged to rotary dislocation, 5 antedislocation, and 5 hind dislocation. All the cases showed the dislocated joint panel of atlantoaxial articulation.Fifteen cases showed deviation of the odontoid process and 8 cases widened distance between the dens and anterior arch of the atlas. The dislocated joint panel of atlantoaxial articulation was more clearly seen with SSD-3D imaging than any other methods. Conclusions:Atlantoaxial subluxation can well be diagnosed by CT 3D reconstruction, in which SSD-3D imaging is optimal.

  7. Moire Ct technique and its application on laser flexible manufacture

    Science.gov (United States)

    Li, Tianze; Hou, Luan; Jiang, Chuan; Zhang, Xia

    2010-10-01

    In the paper, the main properties of Moire fringe, such as average effect, amplification effect, corresponding relation are elaborated, and the principle of Moire Ct technique is represented. On the basis of main features of Moire fringe, multidirectional Moire Ct deflection system is designed using high accuracy Ccd, grating, filter, lens, planar mirror and optical splitter. The system has simple light path, and can be easily made into the one that has large caliber.It can analyze multidirectional records of the probe at the same time, and can obtain clear interference patterns.The iterative technique combined with computer chromatography algorithms is used to achieve inversion of multidirectional clear interference patterns so that the required parameters can be acquired. Moire Ct technique is applied to laser flexible manufacture. Produced parts are delaminated on the paper, and are stratified manufactured until they are connected to forming. Cad/Cam system is adopted to construct Spatial three-dimensional geometric model, and the data files are formed. Then by using the Small triangle plane, the inner and outer surfaces of the data files are discretized. Discretized parts model is made chromatography with mathematical methods using Cam software. A series of parallel horizontal intersecting planes are generated. The problems of filtering arrangement tangent points are solved by recombining the shape and structure relationship among the triangular mesh. Several conclusions are presented.

  8. Application of 3D-myelo-CT for lumbar disease

    Energy Technology Data Exchange (ETDEWEB)

    Taira, Gaku; Endo, Kenji; Karasawa, Haruhiro; Urawa, Yasuhito; Ito, Koichi; Ichimaru, Katsuji [Tokyo Medical Coll., Ami, Ibaraki (Japan). Kasumigaura Hospital; Miura, Yukio

    1997-03-01

    Helical CTs for lumbar disk hernia (LDH) and for lumbar canal stenosis (LCS) were compared with ordinary imaging diagnosis. Subjects were 10 cases of LDH and of LCS, who were 24-71 (mean 58.7) years old. The apparatus was Siemens Somatom Plus 4 and its 3D-program soft was used for reconstruction. The ordinary myelography was performed with a non-ionic contrasting medium and 60 min later, helical CT was carried out with conditions of 140 kV, 204 mA, slice thickness 3 mm, bed speed 3 mm/sec and reconstruction 1.5 mm. MRI was done on sagittal, axial and coronary sections and 3D-MRI was reconstructed from the coronary ones with the maximum intensity projection procedure. The 3D-myelo-CT images were compared with those by myelography, 2D-MRI and 3D-MRI in diagnostic rate of impaired nerve root, anatomical relationships between dura tube and bony factors and imaging rate of redundant nerve root. Exclusions of dura tube and of nerve root were found observable in 3D-myelo-CT, which was useful for surgery simulation and for explaining to patients. (K.H.)

  9. Application of Simulated Three Dimensional CT Image in Orthognathic Surgery

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Hyun Don; Park, Chang Seo [Dept. of Dental Radiology, College of Dentistry, Yensei University, Seoul (Korea, Republic of); Yoo, Sun Kook; Lee, Kyoung Sang [Dept. of Medical Engineering, College of Medicine, Yensei University, Seoul (Korea, Republic of)

    1998-08-15

    In orthodontics and orthognathic surgery, cephalogram has been routine practice in diagnosis and treatment evaluation of craniofacial deformity. But its inherent distortion of actual length and angles during projecting three dimensional object to two dimensional plane might cause errors in quantitative analysis of shape and size. Therefore, it is desirable that three dimensional object is diagnosed and evaluated three dimensionally and three dimensional CT image is best for three dimensional analysis. Development of clinic necessitates evaluation of result of treatment and comparison before and after surgery. It is desirable that patient that was diagnosed and planned by three dimensional computed tomography before surgery is evaluated by three dimensional computed tomography after surgery, too. But Because there is no standardized normal values in three dimension now and three dimensional Computed Tomography needs expensive equipment and because of its expenses and amount of exposure to radiation, limitations still remain to be solved in its application to routine practice. If postoperative three dimensional image is constructed by pre and postoperative lateral and postero-anterior cephalograms and preoperative three dimensional computed tomogram, pre and postoperative image will be compared and evaluated three dimensionally without three dimensional computed tomography after surgery and that will contribute to standardize normal values in three dimension. This study introduced new method that computer-simulated three dimensional image was constructed by preoperative three dimensional computed tomogram and pre and postoperative lateral and postero-anterior cephalograms, and for validation of new method, in four cases of dry skull that position of mandible was displaced and four patients of orthognathic surgery, computer-simulated three dimensional image and actual postoperative three dimensional image were compared. The results were as follows. 1. In four cases of

  10. 75 FR 75548 - SI Financial Group, Inc., Willimantic, CT; Approval of Conversion Application

    Science.gov (United States)

    2010-12-03

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF THE TREASURY Office of Thrift Supervision SI Financial Group, Inc., Willimantic, CT; Approval of Conversion Application Notice is hereby given that on November 10, 2010, the Office of Thrift Supervision approved the application of SI Bancorp, MHC,...

  11. CT equipment and performance issues: radiation protection 162.

    Science.gov (United States)

    Edyvean, S

    2013-02-01

    Since the development of the CT scanner in the early 1970s, CT scanner technology has continuously developed through technical advancement, faster computer processing, superior detectors and helical and multi-detector scanning modes. As a result, the scope of clinical examinations has broadened considerably, and in parallel, this has been achieved with improvement in image quality and radiation dose efficiency. Despite this, and perhaps because image quality can always be improved at the expense of increased radiation dose, CT examinations are among the highest-dose procedures encountered routinely in medical imaging. The qualitative criteria for acceptability in RP 162 address some functional and operational issues, and the quantitative criteria, in the form of suspension levels, focus primarily around hardware aspects of the CT scanner, though consideration is also given to software, operator aspects and selection of scan protocols. Some of the specific aspects and challenges in modern CT systems, in particular multi-slice and wide beams are also addressed.

  12. Applicability of 3D-CT facial reconstruction for forensic individual identification.

    Science.gov (United States)

    Rocha, Sara dos Santos; Ramos, Dalton Luiz; Cavalcanti, Marcelo de Gusmão Paraíso

    2003-01-01

    Computed tomography (CT) is used in several clinical dentistry applications even by axial slices and two and three-dimensional reconstructed images (2D-CT and 3D-CT). The purpose of the current study is to assess the precision of linear measurements made in 3D-CT using craniometric patterns for individual identification in Forensic Dentistry. Five cadaver heads were submitted to a spiral computed tomography using axial slices, and 3D-CT reconstructions were obtained by volume rendering technique with computer graphics tools. Ten (10) craniometric measurements were determined in 3D-CT images by two examiners independently, twice each, and the standard error of intra- and inter-examiner measurements was assessed. The results demonstrated a low standard error of those measurements, from 0.85% to 3.09%. In conclusion, the linear measurements obtained in osseous and soft tissue structures were considered to be precise in 3D-CT with high imaging quality and resolution.

  13. Applicability of 3D-CT facial reconstruction for forensic individual identification

    Energy Technology Data Exchange (ETDEWEB)

    Rocha, Sara dos Santos [Sao Paulo Univ., SP (Brazil). Odontologia Forense; Ramos, Dalton Luiz de Paula [Sao Paulo Univ., SP (Brazil). Dept. of Odontologia Social; Cavalcanti, Marcelo de Gusmao Paraiso [Sao Paulo Univ., SP (Brazil). Dept. de Radiologia

    2003-03-01

    Computed tomography (CT) is used in several clinical dentistry applications even by axial slices and two and three-dimensional reconstructed images (2D-CT and 3D-CT). The purpose of the current study is to assess the precision of linear measurements made in 3D-CT using cranio metric patterns for individual identification in Forensic Dentistry. Five cadaver heads were submitted to a spiral computed tomography using axial slices, and 3D-CT reconstructions were obtained by volume rendering technique with computer graphics tools. Ten (10) cranio metric measurements were determined in 3D-CT images by two examiners independently, twice each, and the standard error of intra- and inter-examiner measurements was assessed. The results demonstrated a low standard error of those measurements, from 0.85% to 3.09%. In conclusion, the linear measurements obtained in osseous and soft tissue structures were considered to be precise in 3D-CT with high imaging quality and resolution. (author)

  14. Comparison of SAPIEN 3 and SAPIEN XT transcatheter heart valve stent-frame expansion: evaluation using multi-slice computed tomography

    Science.gov (United States)

    Kazuno, Yoshio; Maeno, Yoshio; Kawamori, Hiroyuki; Takahashi, Nobuyuki; Abramowitz, Yigal; Babak, Hariri; Kashif, Mohammad; Chakravarty, Tarun; Nakamura, Mamoo; Cheng, Wen; Friedman, John; Berman, Daniel; Makkar, Raj R.; Jilaihawi, Hasan

    2016-01-01

    Aims Stent-frame morphology of the newer-generation, balloon-expandable transcatheter heart valve (THV), the SAPIEN 3 (S3), after transcatheter aortic valve implantation (TAVI) is unknown. We evaluated the THV stent-frame morphology post TAVI of the S3 using multi-slice computed tomography (MSCT) compared with the prior-generation THV, SAPIEN XT (S-XT). Methods and results A total of 94 consecutive participants of RESOLVE registry (NCT02318342) had MSCT after balloon-expandable TAVI (S3 = 39 and S-XT = 55). The morphology of the THV stent-frame was evaluated for expansion area and eccentricity at the THV-inflow, native annulus, mid-THV and THV-outflow levels. Mean %-expansion area for the S3 and the S-XT was 100.9 ± 5.7 and 96.1 ± 5.5%, respectively (P < 0.001). In the S3 group, the THV-inflow level had the largest value of %-expansion area, which decreased from THV-inflow to mid-THV level (105.2 ± 6.4 to 96.5 ± 5.9%, P < 0.001). However, in the S-XT group, %-expansion area increased from THV-inflow level to mid-THV level (93.2 ± 6.2 to 95.1 ± 6.1%, P = 0.0058). On nominal delivery balloon volume, the S3 in 88.5% of cases had overexpansion at the THV-inflow level. The observed degree of THV oversizing of the S3 was significantly lower than the S-XT (6.3 ± 8.6 vs. 11.8 ± 8.5%, P = 0.0027). Nonetheless, the incidence of post-procedural paravalvular aortic regurgitation (PVR) ≥ mild following the S3 TAVI was also significantly lower than the S-XT TAVI (17.9 vs. 43.6%, P = 0.014). Conclusion The newer-generation, balloon-expandable device, the S3, has a flared inflow morphology, whereas the prior-generation device, the S-XT, has relatively constrained inflow morphology post TAVI. This may contribute to a lesser degree of PVR with the S3. PMID:27002141

  15. 口腔颌面锥形束CT与螺旋CT辐射剂量的比较研究%Comparative dosimetry of dental cone-beam computed tomography and multi-slice computed tomography for oral and maxillofacial radiology

    Institute of Scientific and Technical Information of China (English)

    曲兴民; 李刚; 张祖燕; 马绪臣

    2011-01-01

    Objective To compare the effective radiation dose levels of cone beam computed tomography (CBCT) with those of multi-slice computed tomography (MSCT) when scanning the same maxillofacial regions.Methods The effective doses of 2 CBCT( NewTom 9000 and DCT Pro) and 1 MSCT (bright speed edge select 8 slice) scanners were calculated using thermoluminescent dosimeters (TLD) that were placed in a head and neck phantom,and expressed according to the International Commission on Radiation Protection(ICRP) 2007 guidelines.Results Effective dose values ranged from 41.8 to 249.1 μSv for CBCT.The doses of MSCT scanning for maxilla,mandible and maxilla + mandible were 506.7,829.9 and 1066.1 μSv,respectively.Dose levels of scanning only for maxilla or mandible were significantly lower than those for maxilla + mandible.Conclusions When scanning the same maxillofacial regions,the dose levels for NewTom 9000 and DCT Pro CBCT images were lower than those for Bright speed edge select 8 slice MSCT images.Dose levels reduction could be obtained when smaller regions were scanned.%目的 比较口腔颌面锥形束CT与螺旋CT在扫描口腔颌面部相同部位时的辐射剂量,为临床安全有效应用提供实验数据.方法 使用热释光剂量芯片测量两种口腔颌面锥形束CT和一种螺旋CT在扫描头颈部体模上颌、下颌、上颌+下颌时的吸收剂量.按照国际放射防护委员会2007年推荐的组织权重因子,计算各个扫描程序的有效剂量.使用单因素方差分析对所有扫描程序得到的有效剂量进行比较分析,P<0.05为差异有统计学意义.结果 两种口腔颌面锥形束CT的辐射剂量范围41.8 ~249.1 μSv.螺旋CT对上颌、下颌及上颌+下颌进行扫描时的有效剂量分别为506.7、829.9和1066.1 μSv,螺旋CT辐射剂量显著高于两种口腔颌面锥形束CT(P <0.001).同一机型仅进行上颌或下颌扫描的辐射剂量显著低于同时扫描上颌+下颌时

  16. Quality assurance of CT scanning for industrial applications

    DEFF Research Database (Denmark)

    Angel, Jais Andreas Breusch

    ClassWeb through volume comparisons to real dissections of pig carcasses. For the real dissections, volumes of tissue types such as bone, lean meat and fat, are estimated using commercial VolumeGraphics software. It is detected that the ANOVA and the residuals from the virtual dissection fail the normality test...... to 158 μm, compared to average uncertainties below 5.5 μm using CMMs. A test was performed to check if X-ray contrast modalities can be applied for metrological purposes. Traditionally, segmentation between multi-materials in CT scanning is done by using different edge detection techniques and threshold...... to 1348 mL, compared to average uncertainties below 10 mL using the gravimetric method. DMRI and DTU Compute have previously developed advanced image analysis software (PigClassWeb) which performs virtual dissections in pig carcasses. A DOE was carried out to document the performance of Pig...

  17. CT三维重建与颈椎弓根测量%CT three-dimensional reconstruction and cervical pedicle measurement

    Institute of Scientific and Technical Information of China (English)

    于建华; 阿扎提; 刘向峰

    2012-01-01

    BACKGROUND: Three-dimensional reconstruction technique can provide digital three-dimensional model of human internal structure. Surgery design and biomechanical analysis were conducted on the model using relevant software, which can provide reliable data for safe effective implantation of pedicle screw.OBJECTIVE: To review the application of CT three-dimensional reconstruction in cervical pedicle measurement.METHODS: We retrieved PubMed Database, Vip Database and Wanfang Database for literature regarding the application of CT three-dimensional reconstruction in cervical pedicle measurement published from 1990 to 2011. The English key words were “three dimensional reformations of multi-slice spiral CT, cervical pedicle”. The Chinese key words were “cervical pedicle,three-dimensional CT, computer-aided design, spinal surgery, digital orthopedics, medical image”.RESULTS AND CONCLUSION: Using CT three-dimensional reconstruction technique could obtain clear three-dimensional image of cervical vertebra. Due to the great variation of cervical pedicle and complicated anatomic structure, cervical pedicle screw implantation has been used in a few hospitals in China. However, three-dimensional CT reconstruction for measuring cervical pedicle simulated pedicle screw implantation, exactly observed and measured pedicle screw conditions in vivo, and obtained individual anatomic data, which provided guidance for clinical application of pedicle screw implantation.%背景 三维重建技术能够提供人体内部结构的数字化三维模型,并利用相关软件在模型上进行手术设计和生物力学分析,为椎弓根螺钉的安全有效置入提供可靠数据.目的 综述CT 三维重建在颈椎弓根测量中的应用.方法 应用计算机检索1990/2011 PubMed 数据库、维普数据库及万方数据库中有关CT 三维重建在颈椎弓根测量中应用的文献,英文检索词为"three dimensional reformations of multi-slice spiral CT;cervical pedicle

  18. Small-animal CT: Its difference from, and impact on, clinical CT

    Science.gov (United States)

    Ritman, Erik L.

    2007-10-01

    For whole-body computed tomography (CT) images of small rodents, a voxel resolution of at least 10 -3 mm 3 is needed for scale-equivalence to that currently achieved in clinical CT scanners (˜1 mm 3) in adult humans. These "mini-CT" images generally require minutes rather than seconds to complete a scan. The radiation exposure resulting from these mini-CT scans, while higher than clinical CT scans, is below the level resulting in acute tissue damage. Hence, these scans are useful for performing clinical-type diagnostic and monitoring scans for animal models of disease and their response to treatment. "Micro-CT", with voxel size pathological accumulations of metals such as Fe and Ca, which occur in the arterial wall following hemorrhage or tissue damage. Micro-CT can also be used as a test bed for exploring the utility of several modes of X-ray image formation, such as the use of dual-energy X-ray subtraction, X-ray scatter, phase delay and refraction-based imaging for increasing the contrast amongst soft tissue components. With the recent commercial availability of high speed, multi-slice CT scanners which can be operated in dual-energy mode, some of these micro-CT scanner capabilities and insights are becoming implementable in those CT scanners. As a result, the potential diagnostic spectrum that can be addressed with those scanners is broadened considerably.

  19. Automated mapping of clinical terms into SNOMED-CT. An application to codify procedures in pathology.

    Science.gov (United States)

    Allones, J L; Martinez, D; Taboada, M

    2014-10-01

    Clinical terminologies are considered a key technology for capturing clinical data in a precise and standardized manner, which is critical to accurately exchange information among different applications, medical records and decision support systems. An important step to promote the real use of clinical terminologies, such as SNOMED-CT, is to facilitate the process of finding mappings between local terms of medical records and concepts of terminologies. In this paper, we propose a mapping tool to discover text-to-concept mappings in SNOMED-CT. Name-based techniques were combined with a query expansion system to generate alternative search terms, and with a strategy to analyze and take advantage of the semantic relationships of the SNOMED-CT concepts. The developed tool was evaluated and compared to the search services provided by two SNOMED-CT browsers. Our tool automatically mapped clinical terms from a Spanish glossary of procedures in pathology with 88.0% precision and 51.4% recall, providing a substantial improvement of recall (28% and 60%) over other publicly accessible mapping services. The improvements reached by the mapping tool are encouraging. Our results demonstrate the feasibility of accurately mapping clinical glossaries to SNOMED-CT concepts, by means a combination of structural, query expansion and named-based techniques. We have shown that SNOMED-CT is a great source of knowledge to infer synonyms for the medical domain. Results show that an automated query expansion system overcomes the challenge of vocabulary mismatch partially.

  20. Synthesis and characterization of ethosomal contrast agents containing iodine for computed tomography (CT) imaging applications.

    Science.gov (United States)

    Shin, Hanjin; Cho, Young-Min; Lee, Kangtaek; Lee, Chang-Ha; Choi, Byoung Wook; Kim, Bumsang

    2014-06-01

    As a first step in the development of novel liver-specific contrast agents using ethosomes for computed tomography (CT) imaging applications, we entrapped iodine within ethosomes, which are phospholipid vesicular carriers containing relatively high alcohol concentrations, synthesized using several types of alcohol, such as methanol, ethanol, and propanol. The iodine containing ethosomes that were prepared using methanol showed the smallest vesicle size (392 nm) and the highest CT density (1107 HU). The incorporation of cholesterol into the ethosomal contrast agents improved the stability of the ethosomes but made the vesicle size large. The ethosomal contrast agents were taken up well by macrophage cells and showed no cellular toxicity. The results demonstrated that ethosomes containing iodine, as prepared in this study, have potential as contrast agents for applications in CT imaging.

  1. Combined PET/CT in oncology

    Energy Technology Data Exchange (ETDEWEB)

    Kang, Keon Wook [National Cancer Center, Goyang (Korea, Republic of)

    2002-02-01

    Presently, PET is widely used in oncology, but suffers from limitations of poor anatomical information. To compensate for this weakness, a combined PET/CT has been developed by Professor Townsend at the University of Pittsburgh Medical Center. The prototype was designed as PET and CT components combined serially in a gantry. The CT images provide not only accurate anatomical location of the lesions but also transmission map for attenuation correction. More than 300 cancer patients have been studied with the prototype of PET/CT since July, 1998. The PET/TC studies affected the managements in about 20{approx}30% of cancer patients. These changes are a consequence of the more accurate localization of functional abnormalities, and the distinction of pathological from normal physiological uptake. Now a variety of combined PET/CT scanners with high-end PET and high-end CT components are commercially available. With the high speed of multi-slice helical CT, throughput of patient's increases compared to conventional PET. Although some problems (such as a discrepancy in breathing state between the two modalities) still remain, the role of PET/CT in oncology is very promising.

  2. CT fluoroscopy: novel application for the treatment of ventricular pathologies

    Energy Technology Data Exchange (ETDEWEB)

    Murphy, Kieran; Gailloud, Philippe [Johns Hopkins Hospital, Interventional Neuroradiology, Baltimore, MD (United States); Nussbaum, David A. [Hospital of the University of Pennsylvania, Department of Radiology, Philadelphia, PA (United States)

    2007-04-15

    Recent advances in multidetector CT imaging (MDCT) provide real-time ''fluoroscopic-like'' capabilities with excellent spatial resolution. MDCT fluoroscopy expands our ability to perform image-guided interventions in anatomically complex locations. Although MDCT fluoroscopy is currently used at our institution for a variety of procedures ranging from spinal nerve blocks to RFA ablation, we believe these same techniques can be used to navigate within the ventricles of the central nervous system to treat conditions requiring placement of intraventricular catheters, depth electrodes, or potentially stents for the relief of CSF outlet obstruction. Using three fresh, unfrozen human cadavers, we studied the feasibility of using MDCT fluoroscopy for intraventricular catheter placement and to stent the aqueduct of Sylvius. The ventricles were entered via a single needle pass and catheters were placed over the wire. Contrast agent was then injected to visualize the distribution. To stent the aqueduct of Sylvius, a wire was passed into the 4th ventricle and a coronary stent was then inserted over the wire and deployed. Based on our success with these procedures, we believe this technique can be used to limit complications and improve efficacy of a number of neurosurgical procedures. (orig.)

  3. 76 FR 40688 - Foreign-Trade Zone 71-Windsor Locks, CT Application for Expansion

    Science.gov (United States)

    2011-07-11

    ... 8, 1981 (Board Order 177, 46 FR 36220, 7/14/81). The zone currently consists of one site (17.5 acres... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF COMMERCE Foreign-Trade Zones Board Foreign-Trade Zone 71--Windsor Locks, CT Application for Expansion...

  4. Advanced dual-energy CT applications for the evaluation of the soft tissues of the neck.

    Science.gov (United States)

    Forghani, R; Mukherji, S K

    2017-05-02

    There are multiple emerging advanced computed tomography (CT) applications for the evaluation of the neck, many based on dual-energy CT (DECT). DECT is an advanced form of CT in which scan acquisition is performed at two different energies, enabling spectral tissue characterisation beyond what is possible with conventional single-energy CT and potentially providing a new horizon for quantitative analysis and tissue characterisation, particularly in oncological imaging. The purpose of this review is to familiarise the reader with DECT principles and review different clinical applications for the evaluation of the soft tissues of the neck. The article will begin with an overview of DECT scan acquisition, material characterisation, reconstructions, and basic considerations for implementation in the clinical setting. This will then be followed by a review of different clinical applications. The focus will be on oncological imaging, but artefact reduction and other miscellaneous applications will also be discussed. Copyright © 2017 The Royal College of Radiologists. Published by Elsevier Ltd. All rights reserved.

  5. Clinical Utility and Future Applications of PET/CT and PET/CMR in Cardiology

    Science.gov (United States)

    Pan, Jonathan A.; Salerno, Michael

    2016-01-01

    Over the past several years, there have been major advances in cardiovascular positron emission tomography (PET) in combination with either computed tomography (CT) or, more recently, cardiovascular magnetic resonance (CMR). These multi-modality approaches have significant potential to leverage the strengths of each modality to improve the characterization of a variety of cardiovascular diseases and to predict clinical outcomes. This review will discuss current developments and potential future uses of PET/CT and PET/CMR for cardiovascular applications, which promise to add significant incremental benefits to the data provided by each modality alone. PMID:27598207

  6. Multi-slice spiral computed tomography assessment of cardiac diverticula%多层螺旋CT对心脏憩室的诊断价值

    Institute of Scientific and Technical Information of China (English)

    周碧; 赵静; 朱洪章; 杨有优

    2015-01-01

    目的:探讨多层螺旋CT(MSCT)在心脏憩室诊断中的临床价值。方法回顾性分析11例心脏憩室患者的临床及MSCT资料,行多种后处理技术分析心脏憩室形态表现及其他并发异常。结果11例患者心脏憩室均为单发,分别位于左心室(4例)、右心房(3例)、左心房(2例)、右心室(2例)。10例憩室呈囊袋状,1例憩室呈不规则管状,以窄颈与心腔相通,最大径2.5~8.8 cm。本组3例纤维型心室憩室壁薄、伴钙化,2例肌肉型心室憩室壁较厚。3例右心房憩室合并房间隔缺损,1例左心室憩室合并复杂心内外畸形。结论 MSCT能清楚显示心脏憩室位置、形态及大小,可为心室憩室类型判断提供依据,并能提示合并的心内外异常,是较为理想的心脏憩室非侵入性检查手段。%Objective To assess the value of multi-slice spiral computed tomography (MSCT) in the diagnosis of cardiac diverticula. Methods Cardiac MSCT of 11 patients with surgically or pathologically confirmed cardiac diverticula were retrospectively analyzed. Results The cardiac diverticula were isolated and located in the left ventricle (4), right atrium (3), left atrium (2) and right ventricle(2). The diverticula were protruding sac-like(10) or irregular tube-like(1) in shape with longitudinal diameters of 2.5-8.8 cm and were connected to the cardiac cavity by a narrow neck. The diverticular walls were unevenly thin and calcified in 3 fibrous ventricular diverticula and thick in 2 muscular diverticula..Three right atrial diverticula were associated with atrial septal defect and 1 left ventricular diverticulum was accompanied with complex malformations. Conclusion MSCT can clearly depict the location, morphology, size and type of cardiac diverticula and the associated cardiac malformation.

  7. 4D micro-CT for cardiac and perfusion applications with view under sampling

    Energy Technology Data Exchange (ETDEWEB)

    Badea, Cristian T; Johnston, Samuel M; Qi Yi; Johnson, G Allan, E-mail: Cristian.Badea@duke.edu [Center for In Vivo Microscopy, Box 3302, Duke University Medical Center, Durham, NC 27710 (United States)

    2011-06-07

    Micro-CT is commonly used in preclinical studies to provide anatomical information. There is growing interest in obtaining functional measurements from 4D micro-CT. We report here strategies for 4D micro-CT with a focus on two applications: (i) cardiac imaging based on retrospective gating and (ii) pulmonary perfusion using multiple contrast injections/rotations paradigm. A dual source micro-CT system is used for image acquisition with a sampling rate of 20 projections per second. The cardiac micro-CT protocol involves the use of a liposomal blood pool contrast agent. Fast scanning of free breathing mice is achieved using retrospective gating. The ECG and respiratory signals are used to sort projections into ten cardiac phases. The pulmonary perfusion protocol uses a conventional contrast agent (Isovue 370) delivered by a micro-injector in four injections separated by 2 min intervals to allow for clearance. Each injection is synchronized with the rotation of the animal, and each of the four rotations is started with an angular offset of 22.5 from the starting angle of the previous rotation. Both cardiac and perfusion protocols result in an irregular angular distribution of projections that causes significant streaking artifacts in reconstructions when using traditional filtered backprojection (FBP) algorithms. The reconstruction involves the use of the point spread function of the micro-CT system for each time point, and the analysis of the distribution of the reconstructed data in the Fourier domain. This enables us to correct for angular inconsistencies via deconvolution and identify regions where data is missing. The missing regions are filled with data from a high quality but temporally averaged prior image reconstructed with all available projections. Simulations indicate that deconvolution successfully removes the streaking artifacts while preserving temporal information. 4D cardiac micro-CT in a mouse was performed with adequate image quality at isotropic

  8. [Application of adaptive iterative dose reduction technique in CT enterography in diagnosing Crohn disease].

    Science.gov (United States)

    Lian, Yanbang; Cao, Wuteng; Zhu, Shanshan; Lin, Yanghao; Liu, Dechao; Wang, Xinhua; Qiu, Jianping; Zhou, Zhiyang

    2014-07-01

    To evaluate the application of low-dose CT enterography with adaptive iterative dose reduction(AIDR) technique in diagnosing Crohn's disease. Retrospective analysis was performed on 26 patients diagnosed as Crohn's disease by the multidisciplinary team in our hospital. Low-dose CT enterography with 640-slice MDCT was performed on these 26 patients using adaptive iterative dose reduction(AIDR) technique. Characteristics of Crohn's disease in CT enterography images were independently analyzed by two radiologists who were experienced in Crohn's disease with calculating the total radiation dosage. The radiation dosage of 26 patients ranged from 5.58 to 12.90 [mean (9.00±2.00)] mSv, which was lower than conventional scan (around 15 mSv) known from the literatures. According to the images of CT enterography of 26 cases, bowel wall thickening with abnormal enhancement and lymphadenectasis were found in 25 cases with total 109 segmental bowel wall thickening. Among 25 thickening cases, enterostenosis was found in 16 cases, stratification enhancement in 12 cases and comb sign in 14 cases. Besides, it was found that 8 cases with hyperdense fat on the mesenteric side, 7 cases with intestinal fistula, 6 cases with abdominal cavity abscess, and 3 cases with anal fistula. CT enterography of Crohn's disease with adaptive iterative dose reduction technique is an effective method to evaluate Crohn's disease without compromising image quality with reduced radiation dosage.

  9. On-line multi-slice computed tomography interactive overlay with conventional X-ray: a new and advanced imaging fusion concept.

    Science.gov (United States)

    Garcia, Joel A; Bhakta, Shyam; Kay, Joseph; Chan, Kak-Chen; Wink, Onno; Ruijters, Danny; Carroll, John D

    2009-04-17

    Computed tomography (CT) has revolutionized noninvasive cardiovascular evaluations. Complicated percutaneous procedures require precise imaging guidance that conventional X-ray is often unable to provide. By combining X-ray imaging with real-time, interactive, CT-based landmarks, interventional procedures could be facilitated. We describe two cases using the first CT/Live X-ray overlay in which this technology shows its potential. A 31-year-old male with an anatomically complicated atrial septal defect (ASD) was referred for percutaneous closure. Transesophageal echocardiography (TEE) revealed an inferior location of the ASD complicated by it's proximity to a prominent Eustachian ridge. The CT was used to create a patient-specific physical model in preparation for the procedure and an in-lab real-time CT overlay allowing successful closure. A second case of a 41-year-old male with coronary artery disease status-post coronary artery bypass, aortic valve replacement (AVR), and aortic root replacement with an abnormal coronary computed tomography angiogram (CTA). In a prior procedure years ago the saphenous vein graft (SVG) to the left anterior descending artery (LAD) could not be cannulated during invasive angiography, given the patient's complicated and unusual anatomy. Using CT overlay, the superiorly and anteriorly located SVG was cannulated successfully. CT/Live X-ray overlay provided an adequate anatomical intra-procedural ASD evaluation, defect sizing, and guidance in one case and localization of an anatomically challenging graft ostium in the other case. Adding the CT landmarks as an overlay to traditional X-ray techniques provides a revolutionary and advanced imaging fusion concept that should improve procedural success.

  10. Centre for Industrial Application of CT scanning (CIA-CT) – Four years of results 2009-2013

    DEFF Research Database (Denmark)

    De Chiffre, Leonardo; Andreasen, Jan Lasson; Christensen, Lars Bager;

    as a centre of excellence for industrial CT scanning, both nationally and internationally. A network with approx. 40 participants has been established, and a total of 22 students have been educated. Dissemination activities have encompassed: a web page www.cia-ct.mek.dtu.dk , 8 newsletters, 4 topical...

  11. Investigation of the usability of conebeam CT data sets for dose calculation

    Directory of Open Access Journals (Sweden)

    Wilbert Jürgen

    2008-12-01

    Full Text Available Abstract Background To investigate the feasibility and accuracy of dose calculation in cone beam CT (CBCT data sets. Methods Kilovoltage CBCT images were acquired with the Elekta XVI system, CT studies generated with a conventional multi-slice CT scanner (Siemens Somatom Sensation Open served as reference images. Material specific volumes of interest (VOI were defined for commercial CT Phantoms (CATPhan® and Gammex RMI® and CT values were evaluated in CT and CBCT images. For CBCT imaging, the influence of image acquisition parameters such as tube voltage, with or without filter (F1 or F0 and collimation on the CT values was investigated. CBCT images of 33 patients (pelvis n = 11, thorax n = 11, head n = 11 were compared with corresponding planning CT studies. Dose distributions for three different treatment plans were calculated in CT and CBCT images and differences were evaluated. Four different correction strategies to match CT values (HU and density (D in CBCT images were analysed: standard CT HU-D table without adjustment for CBCT; phantom based HU-D tables; patient group based HU-D tables (pelvis, thorax, head; and patient specific HU-D tables. Results CT values in the CBCT images of the CATPhan® were highly variable depending on the image acquisition parameters: a mean difference of 564 HU ± 377 HU was calculated between CT values determined from the planning CT and CBCT images. Hence, two protocols were selected for CBCT imaging in the further part of the study and HU-D tables were always specific for these protocols (pelvis and thorax with M20F1 filter, 120 kV; head S10F0 no filter, 100 kV. For dose calculation in real patient CBCT images, the largest differences between CT and CBCT were observed for the standard CT HU-D table: differences were 8.0% ± 5.7%, 10.9% ± 6.8% and 14.5% ± 10.4% respectively for pelvis, thorax and head patients using clinical treatment plans. The use of patient and group based HU-D tables resulted in

  12. Application of the optically stimulated luminescence (OSL) technique for mouse dosimetry in micro-CT imaging

    Energy Technology Data Exchange (ETDEWEB)

    Vrigneaud, Jean-Marc; Courteau, Alan; Oudot, Alexandra; Collin, Bertrand [Department of Nuclear Medicine, Centre Georges-François Leclerc, 1 rue Professeur Marion, Dijon 21079 Cedex (France); Ranouil, Julien [Landauer Europe, 33 avenue du Général Leclerc, Fontenay-aux-Roses 92266 Cedex (France); Morgand, Loïc; Raguin, Olivier [Oncodesign, 20 rue Jean Mazen, Dijon 21076 Cedex (France); Walker, Paul [LE2i CNRS UMR 5158, Faculty of Medicine, BP 87900, 21079 Dijon Cedex (France); Brunotte, François [Department of Nuclear Medicine, Centre Georges-François Leclerc, 1 rue Professeur Marion, Dijon 21079 Cedex, France and LE2i CNRS UMR 5158, Faculty of Medicine, BP 87900, 21079 Dijon Cedex (France)

    2013-12-15

    Purpose: Micro-CT is considered to be a powerful tool to investigate various models of disease on anesthetized animals. In longitudinal studies, the radiation dose delivered by the micro-CT to the same animal is a major concern as it could potentially induce spurious effects in experimental results. Optically stimulated luminescence dosimeters (OSLDs) are a relatively new kind of detector used in radiation dosimetry for medical applications. The aim of this work was to assess the dose delivered by the CT component of a micro-SPECT (single-photon emission computed tomography)/CT camera during a typical whole-body mouse study, using commercially available OSLDs based on Al{sub 2}O{sub 3}:C crystals.Methods: CTDI (computed tomography dose index) was measured in micro-CT with a properly calibrated pencil ionization chamber using a rat-like phantom (60 mm in diameter) and a mouse-like phantom (30 mm in diameter). OSLDs were checked for reproducibility and linearity in the range of doses delivered by the micro-CT. Dose measurements obtained with OSLDs were compared to those of the ionization chamber to correct for the radiation quality dependence of OSLDs in the low-kV range. Doses to tissue were then investigated in phantoms and cadavers. A 30 mm diameter phantom, specifically designed to insert OSLDs, was used to assess radiation dose over a typical whole-body mouse imaging study. Eighteen healthy female BALB/c mice weighing 27.1 ± 0.8 g (1 SD) were euthanized for small animal measurements. OLSDs were placed externally or implanted internally in nine different locations by an experienced animal technician. Five commonly used micro-CT protocols were investigated.Results: CTDI measurements were between 78.0 ± 2.1 and 110.7 ± 3.0 mGy for the rat-like phantom and between 169.3 ± 4.6 and 203.6 ± 5.5 mGy for the mouse-like phantom. On average, the displayed CTDI at the operator console was underestimated by 1.19 for the rat-like phantom and 2.36 for the mouse

  13. Evaluating applicability of metal artifact reduction algorithm for head and neck radiation treatment planning CT

    Energy Technology Data Exchange (ETDEWEB)

    Son, Sang Jun; Park, Jang Pil; Kim, Min Jeong; Yoo, Suk Hyun [Dept. of Radiation Oncology, Seoul National University Hospital, Seoul (Korea, Republic of)

    2014-06-15

    The purpose of this study is evaluation for the applicability of O-MAR(Metal artifact Reduction for Orthopedic Implants)(ver. 3.6.0, Philips, Netherlands) in head and neck radiation treatment planning CT with metal artifact created by dental implant. All of the in this study's CT images were scanned by Brilliance Big Bore CT(Philips, Netherlands) at 120 kVp, 2 mm sliced and Metal artifact reduced by O-MAR. To compare the original and reconstructed CT images worked on RTPS(Eclipse ver 10.0.42, Varian, USA). In order to test the basic performance of the O-MAR, The phantom was made to create metal artifact by dental implant and other phantoms used for without artifact images. To measure a difference of HU in with artifact images and without artifact images, homogeneous phantom and inhomogeneous phantoms were used with cerrobend rods. Each of images were compared a difference of HU in ROIs. And also, 1 case of patient's original CT image applied O-MAR and density corrected CT were evaluated for dose distributions with SNC Patient(Sun Nuclear Co., USA). In cases of head and neck phantom, the difference of dose distribution is appeared 99.8% gamma passing rate(criteria 2 mm / 2%) between original and CT images applied O-MAR. And 98.5% appeared in patient case, among original CT, O-MAR and density corrected CT. The difference of total dose distribution is less than 2% that appeared both phantom and patient case study. Though the dose deviations are little, there are still matters to discuss that the dose deviations are concentrated so locally. In this study, The quality of all images applied O-MAR was improved. Unexpectedly, Increase of max. HU was founded in air cavity of the O-MAR images compare to cavity of the original images and wrong corrections were appeared, too. The result of study assuming restrained case of O-MAR adapted to near skin and low density area, it appeared image distortion and artifact correction simultaneously. In O-MAR CT, air cavity area

  14. Clinical Applications of a CT Window Blending Algorithm: RADIO (Relative Attenuation-Dependent Image Overlay).

    Science.gov (United States)

    Mandell, Jacob C; Khurana, Bharti; Folio, Les R; Hyun, Hyewon; Smith, Stacy E; Dunne, Ruth M; Andriole, Katherine P

    2017-06-01

    A methodology is described using Adobe Photoshop and Adobe Extendscript to process DICOM images with a Relative Attenuation-Dependent Image Overlay (RADIO) algorithm to visualize the full dynamic range of CT in one view, without requiring a change in window and level settings. The potential clinical uses for such an algorithm are described in a pictorial overview, including applications in emergency radiology, oncologic imaging, and nuclear medicine and molecular imaging.

  15. Multislice CT brain image registration for perfusion studies

    Science.gov (United States)

    Lin, Zhong Min; Pohlman, Scott; Chandra, Shalabh

    2002-04-01

    During the last several years perfusion CT techniques have been developed as an effective technique for clinically evaluating cerebral hemodynamics. Perfusion CT techniques are capable of measurings functional parameters such as tissue perfusion, blood flow, blood volume, and mean transit time and are commonly used to evaluate stroke patients. However, the quality of functional images of the brain frequently suffers from patient head motion. Because the time window for an effective treatment of stroke patient is narrow, a fast motion correction is required. The purpose of the paper is to present a fast and accurate registration technique for motion correction of multi-slice CT and to demonstrate the effects of the registration on perfusion calculation.

  16. Monte Carlo simulations of a high-resolution X-ray CT system for industrial applications

    Science.gov (United States)

    Miceli, A.; Thierry, R.; Flisch, A.; Sennhauser, U.; Casali, F.; Simon, M.

    2007-12-01

    An X-ray computed tomography (CT) model based on the GEANT4 Monte Carlo code was developed for simulation of a cone-beam CT system for industrial applications. The full simulation of the X-ray tube, object, and area detector was considered. The model was validated through comparison with experimental measurements of different test objects. There is good agreement between the simulated and measured projections. To validate the model we reduced the beam aperture of the X-ray tube, using a source-collimator, to decrease the scattered radiation from the CT system structure and from the walls of the X-ray shielding room. The degradation of the image contrast using larger beam apertures is also shown. Thereafter, the CT model was used to calculate the spatial distribution and the magnitude of the scattered radiation from different objects. It has been assessed that the scatter-to-primary ratio (SPR) is below 5% for small aluminum objects (approx. 5 cm path length), and in the case of large aluminum objects (approx. 20 cm path length) it can reach up to a factor of 3 in the region corresponding to the maximum path length. Therefore, the scatter from the object significantly affects quantitative accuracy. The model was also used to evaluate the degradation of the image contrast due to the detector box.

  17. Evaluation of a metal artifact reduction algorithm applied to post-interventional flat detector CT in comparison to pre-treatment CT in patients with acute subarachnoid haemorrhage

    Energy Technology Data Exchange (ETDEWEB)

    Mennecke, Angelika; Svergun, Stanislav; Doerfler, Arnd; Struffert, Tobias [University of Erlangen-Nuremberg, Department of Neuroradiology, Erlangen (Germany); Scholz, Bernhard [Siemens Healthcare GmbH, Forchheim (Germany); Royalty, Kevin [Siemens Medical Solutions, USA, Inc., Hoffman Estates, IL (United States)

    2017-01-15

    Metal artefacts can impair accurate diagnosis of haemorrhage using flat detector CT (FD-CT), especially after aneurysm coiling. Within this work we evaluate a prototype metal artefact reduction algorithm by comparison of the artefact-reduced and the non-artefact-reduced FD-CT images to pre-treatment FD-CT and multi-slice CT images. Twenty-five patients with acute aneurysmal subarachnoid haemorrhage (SAH) were selected retrospectively. FD-CT and multi-slice CT before endovascular treatment as well as FD-CT data sets after treatment were available for all patients. The algorithm was applied to post-treatment FD-CT. The effect of the algorithm was evaluated utilizing the pre-post concordance of a modified Fisher score, a subjective image quality assessment, the range of the Hounsfield units within three ROIs, and the pre-post slice-wise Pearson correlation. The pre-post concordance of the modified Fisher score, the subjective image quality, and the pre-post correlation of the ranges of the Hounsfield units were significantly higher for artefact-reduced than for non-artefact-reduced images. Within the metal-affected slices, the pre-post slice-wise Pearson correlation coefficient was higher for artefact-reduced than for non-artefact-reduced images. The overall diagnostic quality of the artefact-reduced images was improved and reached the level of the pre-interventional FD-CT images. The metal-unaffected parts of the image were not modified. (orig.)

  18. 4D micro-CT for cardiac and perfusion applications with view under sampling

    Science.gov (United States)

    Badea, Cristian T.; Johnston, Samuel M.; Qi, Yi; Johnson, G. Allan

    2011-06-01

    Micro-CT is commonly used in preclinical studies to provide anatomical information. There is growing interest in obtaining functional measurements from 4D micro-CT. We report here strategies for 4D micro-CT with a focus on two applications: (i) cardiac imaging based on retrospective gating and (ii) pulmonary perfusion using multiple contrast injections/rotations paradigm. A dual source micro-CT system is used for image acquisition with a sampling rate of 20 projections per second. The cardiac micro-CT protocol involves the use of a liposomal blood pool contrast agent. Fast scanning of free breathing mice is achieved using retrospective gating. The ECG and respiratory signals are used to sort projections into ten cardiac phases. The pulmonary perfusion protocol uses a conventional contrast agent (Isovue 370) delivered by a micro-injector in four injections separated by 2 min intervals to allow for clearance. Each injection is synchronized with the rotation of the animal, and each of the four rotations is started with an angular offset of 22.5 from the starting angle of the previous rotation. Both cardiac and perfusion protocols result in an irregular angular distribution of projections that causes significant streaking artifacts in reconstructions when using traditional filtered backprojection (FBP) algorithms. The reconstruction involves the use of the point spread function of the micro-CT system for each time point, and the analysis of the distribution of the reconstructed data in the Fourier domain. This enables us to correct for angular inconsistencies via deconvolution and identify regions where data is missing. The missing regions are filled with data from a high quality but temporally averaged prior image reconstructed with all available projections. Simulations indicate that deconvolution successfully removes the streaking artifacts while preserving temporal information. 4D cardiac micro-CT in a mouse was performed with adequate image quality at isotropic

  19. 多层螺旋CT小肠造影对克罗恩病的诊断价值%Application of multislice CT enterography in diagnosis of Crohn's diease

    Institute of Scientific and Technical Information of China (English)

    张琳; 汤光宇; 李伟; 刘勇; 陈云燕

    2012-01-01

    目的 探讨多层螺旋CT小肠造影(multi-slice CT enterography,MSCTE)对肠管克罗恩病(Crohn's diease,CD)的诊断价值.方法 对48例临床疑似CD患者进行MSCTE检查,对照肠镜、病理结果,计算其诊断敏感性、特异性,并分析CD的影像学表现,包括发生部位、肠壁增厚程度、强化程度及增强特点、肠腔狭窄程度、并发症及周围脏器受累情况.结果 MSCTE诊断CD的敏感性为89.2%,特异性为36.4%.CD最常见发生部分为末端回肠(81.1%).影像学表现为:肠壁环形增厚(89.2%),黏膜明显强化(97.3%),黏膜面毛糙,肠壁分层状强化(88.9%),肠腔节段性中-重度狭窄(86.7%).并发症包括肠梗阻、肠系膜淋巴结增生、梳征(肠系膜血管增粗)、肠瘘.结论 MSCTE是CD的重要影像学检查方法,在CD的诊断、活动性判断及肠外并发症的显示中具有重要意义,结合肠镜、病理结果,有助于提高诊断准确性.%Objective To evaluate the application of multislice CT enterography (MSCTE) in diagnosis of Crohn's diease. Methods MSCTE were performed in 48 patients with suspected Crohn's disease (CD). Using enteroscopy and pathological findings as gold standard, the sensitivity and specificity of MSCTE imaging in diagnosis of Crohn's disease were analyzed. Results The diagnostic sensitivity and specificity of MSCTE were 89. 2% and 36.4% respectively. The terminal ileum was the most frequently involved in CD (81.1% ). The most common signs of MSCTE were annular thickness of intestinal wall (89. 2%), mucosal hyperenhancement (97. 3%),mucosal surface coarse, mural stratification enhancement (88. 9% ), moderate to severe segmental luminal narrowing (86. 7% ). The common complications were ileus, mesenteric lymph nodes and the comb sign (prominent vasa recta) and intestinal fistula. Conclusion MSCTE is' of value in diagnosis of CD and its complications. MSCTE combined with enteroscopy, pathology and clinical manifestation can improve

  20. Study on the application value of CT perfusion imaging in patients with hepatic carcinoma

    Institute of Scientific and Technical Information of China (English)

    Yu-Gang Zhou; Cheng-Zhou Yu; Xi-Qun Liu

    2016-01-01

    Objective:To research and discuss the application value of CT perfusion imaging in patients with hepatic carcinoma.Methods: A total of 47 patients with hepatic carcinoma in our hospital from Januarey 2014 to August 2015 were selected as study group; meanwhile the contemporaneous 47 patients with benign liver disease were selected as control group. Then the CT perfusion imaging parameters of hepatic carcinoma patients in control group and study group, and hepatic carcinoma patients with different types and stages in study group were respectively compared and the relationship between above indexes and hepatic carcinoma were analyzed by Logistic Analysis.Results:The BF, BV, HAI, MTT, PS and HAP levels in study group were all higher than that in control group, while the PVP level was lower than that in control group, and the detection results between hepatic carcinoma patients with different stages in study group also had obvious difference, statistical results of patients with higher stages were all worse than those of patients with lower stages, but the above statistical results among hepatic carcinoma patients with different types had no obvious difference, and the above detection indexes all had close relations with hepatic carcinoma by Logistic Analysis. Conclusion:The application value of CT perfusion imaging in patients with hepatic carcinoma was high, and it had active reaction value for the lesion blood flow of patients with hepatic carcinoma, and it also had high clinical value for the stages of disease.

  1. Applications of PET-CT in clinical practice: Present and future

    Energy Technology Data Exchange (ETDEWEB)

    Costa, Durval Campos [IBILI, Faculdade de Medicina da Universidade de Coimbra, P-3000 Coimbra (Portugal)]. E-mail: dcosta@ibili.uc.pt

    2007-02-15

    Radionuclide imaging and specially positron emission tomography (PET) has already demonstrated its benefits in three major medical subjects, i.e. neurology, cardiology and particularly clinical oncology. More recently the combination of PET and X-ray computed tomography (CT) as PET-CT led to a significant increment of the already large number of clinical applications of this imaging modality. This 'anatomy-metabolic fusion' also known as Metabolic Imaging has its future assured if we can: (1) improve resolution reducing partial volume effect, (2) achieve very fast whole body imaging (3) obtain accurate quantification of specific functions with higher contrast resolution and, if possible, (4) reduce exposure rates due to the unavoidable use of ionizing radiation.

  2. Tracking fuzzy borders using geodesic curves with application to liver segmentation on planning CT.

    Science.gov (United States)

    Yuan, Yading; Chao, Ming; Sheu, Ren-Dih; Rosenzweig, Kenneth; Lo, Yeh-Chi

    2015-07-01

    This work aims to develop a robust and efficient method to track the fuzzy borders between liver and the abutted organs where automatic liver segmentation usually suffers, and to investigate its applications in automatic liver segmentation on noncontrast-enhanced planning computed tomography (CT) images. In order to track the fuzzy liver-chestwall and liver-heart borders where oversegmentation is often found, a starting point and an ending point were first identified on the coronal view images; the fuzzy border was then determined as a geodesic curve constructed by minimizing the gradient-weighted path length between these two points near the fuzzy border. The minimization of path length was numerically solved by fast-marching method. The resultant fuzzy borders were incorporated into the authors' automatic segmentation scheme, in which the liver was initially estimated by a patient-specific adaptive thresholding and then refined by a geodesic active contour model. By using planning CT images of 15 liver patients treated with stereotactic body radiation therapy, the liver contours extracted by the proposed computerized scheme were compared with those manually delineated by a radiation oncologist. The proposed automatic liver segmentation method yielded an average Dice similarity coefficient of 0.930 ± 0.015, whereas it was 0.912 ± 0.020 if the fuzzy border tracking was not used. The application of fuzzy border tracking was found to significantly improve the segmentation performance. The mean liver volume obtained by the proposed method was 1727 cm(3), whereas it was 1719 cm(3) for manual-outlined volumes. The computer-generated liver volumes achieved excellent agreement with manual-outlined volumes with correlation coefficient of 0.98. The proposed method was shown to provide accurate segmentation for liver in the planning CT images where contrast agent is not applied. The authors' results also clearly demonstrated that the application of tracking the fuzzy

  3. Clinical application of 64-slice spiral CT in the diagnosis of the Tetralogy of Fallot

    Energy Technology Data Exchange (ETDEWEB)

    Wang Ximing [Tianjin Medical University, Tianjin City (China) and Shandong Medical Imaging Research Institute, Jinan City, Shandong Province 250021 (China)], E-mail: wxming369@163.com.cn; Wu Lebin [Shandong Medical Imaging Research Institute, Jinan City, Shandong Province 250021 (China); Sun Cong [Shandong Medical Imaging Research Institute, Jinan City, Shandong Province 250021 (China); Shandong University Medical College, Shandong Jinan 250012 (China); Liu Cheng [Shandong Medical Imaging Research Institute, Jinan City, Shandong Province 250021 (China); Chao, Bao-Ting [Shandong University Medical College, Shandong Jinan 250012 (China); Han Bo [Shandong Provincial Hospital Pediatric Department, Shandong, Jinan 250021 (China); Zhang Yunting [Tianjin Medical University, General Hospital MR Department, Tianjin City (China); Chen Haisong [Shandong Medical Imaging Research Institute, Jinan City, Shandong Province 250021 (China); Shandong University Medical College, Shandong Jinan 250012 (China); Li Zhenjia [Shandong Medical Imaging Research Institute, Jinan City, Shandong Province 250021 (China)

    2007-11-15

    Objective: To explore the clinical application of 64-slice spiral CT in the diagnosis of the Tetralogy of Fallot. Methods: Eighteen patients with diagnosed Tetralogy of Fallot underwent cardiac CT angiography with 64-slice CT (CTA). Two- and three-dimensional images were used for diagnosing in all cases by means of MPR (coronal, sagital and oblique), cMPR, MIP and VRT. Results: All patients had ventricular septal defect, pulmonary stenosis and hypertrophy of right ventricle. The morphologic features of Tetralogy of Fallot were equal to echocardiography. Patent ductus arteriosus (PDA) were detected on eight patients. Main coronary artery branches and partial sub-branches were visualized in all patients. Abnormal coronary arteries were found in seven cases: both left and right main coronary artery arising from the right aortic sinus one case, right main coronary artery and circumflex (CX) arising from the right aortic sinus one case, left anterior descending (LAD) and CX arising from left aortic sinus directly one case, left and right coronary artery arising from back and front of the aortic sinus, respectively, three cases. Pulmonary artery branch stenosis was found in 12 cases and branch pulmonary artery dilation noticed in 1 case. Double superior vena cava was also found in one case. According to the surgery the diagnostic accuracy of CT and Echocardiography was 95.45 and 83.33%, respectively. Conclusion: Two- and three-dimensional 64-slice CTA not only show the overall anatomical structure of the heart, but also show coronary and pulmonary arteries. With these results, evaluation of coronary anomalies and pulmonary artery stenosis with 64-MSCT is extremely valuable for planning the operative procedure on the patients with Tetralogy of Fallot.

  4. [MR-urography and CT-urography: principles, examination techniques, applications].

    Science.gov (United States)

    Nolte-Ernsting, C; Staatz, G; Wildberger, J; Adam, G

    2003-02-01

    MR-urography (MRU) and CT-urography (CTU) provide refined imaging of the upper urinary tract not achievable with conventional intravenous urography (IVU). The traditional MR-urographic technique utilizes unenhanced, heavily T2 -weighted turbo spin-echo sequences for obtaining static fluid images of the urinary tract independent of the excretory renal function. T2 -weighted MR-urograms have proved to be excellent in visualizing the dilated urinary tract, even in non-excreting kidneys. In contrast, T1 -weighted MRU reflects the excretory renal function and displays the urine flow through the upper tract after renal excretion of an intravenously administered gadolinium chelate. The gadolinium-enhanced urine is visualized with fast T1 -weighted 3D-gradient-echo sequences. The combination of gadolinium and low-dose furosemide (5 - 10 mg) is the key for achieving a uniform distribution of gadolinium in the collecting system and for avoiding susceptibility artifacts (T2*-effects) in the urine. T1 -weighted excretory MRU provides impressive urograms of both non-dilated and obstructed collecting systems in patients with normal or moderately impaired renal function. Multislice-CT-urography (MS-CTU) is also an excretory urography like T1 -weighted MRU. Furthermore, MS-CTU can be combined with low-dose furosemide for accelerated passage of excreted contrast material obviating the need for abdominal compression. CT-urography is limited by its radiation burden and the nephrotoxicity of radiographic contrast media. Combining MRU or MS-CTU with conventional MRI or CT offers several applications, e.g., diagnosis of intrinsic and extrinsic tumors. Meanwhile, MRU has replaced IVU in pediatric uroradiology and is also recommended for the assessment of renal transplants. MS-CTU may provide valuable information in chronic urolithiasis, especially if associated with a distorted urinary tract anatomy. Both MRU and MS-CTU will play an important role in modern uroradiology.

  5. 64 Slice Spiral CT and Mammography for the Diagnosis of Comparative Study of Breast Carcinoma in Imaging%64排螺旋CT与钼靶摄影在影像诊断乳腺癌中的对比研究

    Institute of Scientific and Technical Information of China (English)

    赵宝贵

    2014-01-01

    Objective To explore the application value of multislice spiral CT and mammography in the diagnosis of breast cancer. Methods Retrospective analysis of the 60 cases of breast cancer confirmed by pathology and plain scan, enhanced and image reconstruction. Results In 60 cases of breast cancer were mass type,57 cases showed irregular shape,48 cases of edge see burr,8 cases of skin changes,4 cases of skin retraction,surrounding invasion in 12 cases, axillary lymph nodes seen in 32 cases,mediastinal lymph nodes and lung metastasis. Enhanced masses enhanced obviously, the increase of CT value (18~83) Hu,parallel reconstruction makes mass surrounding structure is stereoscopic display. Conclusion Multi slice spiral CT examination has certain application value in the diagnosis of breast cancer.%目的:探讨多层螺旋 CT 及钼靶摄影在乳腺癌诊断中的应用价值。方法回顾性分析经病理证实的60例乳腺癌平扫,增强及重建图像。结果60例乳腺癌均为肿块型,57例表现为不规则形,48例边缘见毛刺,8例皮肤改变,4例皮肤内陷,周围侵犯12例,32例见腋窝淋巴结,纵隔淋巴结及肺内转移。增强后肿块强化明显,CT 值升高(18~83)hu,并行重建使肿块周边结构呈立体显示。结论多层螺旋 CT 检查在乳腺癌定性诊断中有一定的应用价值。

  6. 双源CT的临床应用进展%Development and Clinical Application of Dual-Source CT

    Institute of Scientific and Technical Information of China (English)

    徐辉; 殷信道; 吴旻

    2014-01-01

    In 2005 and 2008, Siemens launched the 昀rst and second generation Dual Source CT system. This paper reviews the basic structure, characteristics, advantages and application of Dual Source CT system.%2005年、2008年西门子相继推出第一代双源CT Definition(Dual Source Computed Tomography, DSCT)、第二代双源CT(SOMATOM De昀nition Flash),本文主要就双源CT的基本结构、特点、优势以及在临床应用方面的进展作一综述。

  7. Investigation on the prospects of multi-slice computed tomography enterography in diagnosing small intestine tumor%CT小肠造影在诊断小肠肿瘤中的应用价值

    Institute of Scientific and Technical Information of China (English)

    徐莹; 陈业媛; 舒虹; 肖香佐

    2015-01-01

    目的:探讨多层螺旋CT小肠造影(MSCTE)在小肠肿瘤诊断中的应用价值。方法回顾性分析经手术病理证实的45例小肠肿瘤的MSCTE影像表现,总结其影像学表现特点。结果45例小肠肿瘤中,良性肿瘤9例,其中脂肪瘤6例,影像表现为腔内含脂肪低密度肿块影;腺瘤2例,表现为腔内均质的软组织肿块;回肠系膜淋巴管瘤1例,表现为不规则囊性病灶。常见的恶性肿瘤34例,其中腺癌14例,表现为肠壁局限不规则的环形增厚,中度不均匀强化;间质瘤11例,表现为较大的软组织肿块,以腔外生长为主,密度不均匀,中度或明显强化,常伴有囊变、坏死;淋巴瘤9例,肠壁不规则增厚或形成软组织肿块,累及肠段较长,均匀轻中度强化,常伴有肠系膜、腹膜后淋巴结肿大。少见的恶性肿瘤2例,转移瘤1例,表现为多发肠壁不规则增厚,明显强化,腹壁出现转移性结节;类癌1例,右下腹不规则肿块影。结论 MSCTE在小肠肿瘤诊断与鉴别诊断中有较好的临床应用价值。%Objective To investigate application prospects of Multi-slice computed tomography Enterography(MSCTE) in diag-nosing small intestine tumor (SIT). Methods MSCTE findings were retrospectively analyzed in 45 cases of SIT diagnosed patho-logically after surgery and were summarized in terms of imaging features. Results Of all 45 cases of SIT,9 were benign ones and 6 were lipoma,characterized by low-density mass shadow in intestinal cavity;2 were adenoma,characterized by homogeneous soft tissue mass in intestinal cavity;1 belonged to ileac mesentery lymphangioma,characterized by irregular cyst-like focus;34 were the most common type of malignancies,14 of which were adenocarcinoma,characterized by localized ring-formed thickening of in-testinal wall with moderate heterogeneous enhancement;11 were mesenchymoma,characterized by soft tissue mass relatively big in

  8. The Potential Application of Raw Cadmium Sulfide Nanoparticles as CT Photographic Developer.

    Science.gov (United States)

    Wu, Qiang; Huang, Lingxin; Li, Zhan; An, Wenzhen; Liu, Dan; Lin, Jin; Tian, Longlong; Wang, Xinling; Liu, Bo; Qi, Wei; Wu, Wangsuo

    2016-12-01

    With the development of science and technology, new applications about nanoparticles should be explored to achieve full-scale knowledge. Therefore, in this work, the toxicity and potential application of raw cadmium sulfide nanoparticles (CdS) in vivo were further studied through ICP-OES and CTs. Surprisingly, CdS exhibited an excellent photographic property, except for finding the accumulation of CdS in the lungs, liver, spleen, and kidney with a strong dependence on time; it is also found that there were a significant uptake in the pancreas for an obvious CT imaging. And the following investigations showed that the raw CdS could damage the tissues accumulating nanoparticles. Through this work, it can be seen that the raw CdS being modified might be an excellent photographic developer for detecting cancers or other diseases.

  9. The Potential Application of Raw Cadmium Sulfide Nanoparticles as CT Photographic Developer

    Science.gov (United States)

    Wu, Qiang; Huang, Lingxin; Li, Zhan; An, Wenzhen; Liu, Dan; Lin, Jin; Tian, Longlong; Wang, Xinling; Liu, Bo; Qi, Wei; Wu, Wangsuo

    2016-04-01

    With the development of science and technology, new applications about nanoparticles should be explored to achieve full-scale knowledge. Therefore, in this work, the toxicity and potential application of raw cadmium sulfide nanoparticles (CdS) in vivo were further studied through ICP-OES and CTs. Surprisingly, CdS exhibited an excellent photographic property, except for finding the accumulation of CdS in the lungs, liver, spleen, and kidney with a strong dependence on time; it is also found that there were a significant uptake in the pancreas for an obvious CT imaging. And the following investigations showed that the raw CdS could damage the tissues accumulating nanoparticles. Through this work, it can be seen that the raw CdS being modified might be an excellent photographic developer for detecting cancers or other diseases.

  10. Current Roles and Future Applications of Cardiac CT: Risk Stratification of Coronary Artery Disease

    Energy Technology Data Exchange (ETDEWEB)

    Yoon, Yeonyee Elizabeth [Department of Cardiology, Cardiovascular Center, Seoul National University Bundang Hospital, Seongnam 463-707 (Korea, Republic of); Lim, Tae-Hwan [Department of Radiology and Research Institute of Radiology, University of Ulsan College of Medicine, Asan Medical Center, Seoul 138-736 (Korea, Republic of)

    2014-07-01

    Cardiac computed tomography (CT) has emerged as a noninvasive modality for the assessment of coronary artery disease (CAD), and has been rapidly integrated into clinical cares. CT has changed the traditional risk stratification based on clinical risk to image-based identification of patient risk. Cardiac CT, including coronary artery calcium score and coronary CT angiography, can provide prognostic information and is expected to improve risk stratification of CAD. Currently used conventional cardiac CT, provides accurate anatomic information but not functional significance of CAD, and it may not be sufficient to guide treatments such as revascularization. Recently, myocardial CT perfusion imaging, intracoronary luminal attenuation gradient, and CT-derived computed fractional flow reserve were developed to combine anatomical and functional data. Although at present, the diagnostic and prognostic value of these novel technologies needs to be evaluated further, it is expected that all-in-one cardiac CT can guide treatment and improve patient outcomes in the near future.

  11. Characteristics and diagnosis of multi-slice computed tomography examination of portal vein diseases%门静脉病变的多排螺旋CT检查特征与诊断

    Institute of Scientific and Technical Information of China (English)

    任小军; 潘高争; 王霞; 杨如武

    2015-01-01

    恶性肿瘤引起胆管梗阻17例,肝硬化门静脉海绵样变伴肝内胆管扩张(门静脉高压性胆管病)2例.结论 门静脉病变多排螺旋CT检查主要表现为门静脉狭窄、闭塞或扩张、积气,其继发病变表现为门-腔静脉侧支循环形成及门静脉海绵样变、肠缺血以及门静脉高压性胆病;其原发病变多样,以肝硬化和恶性肿瘤为主.多排螺旋CT检查可清楚显示门静脉病变,对其原发病变与继发病变可进行准确诊断.%Objective To summarize the characteristics of multi-slice computed tomography (MSCT) of portal vein diseases and investigate the CT diagnosis of its primary and secondary diseases.Methods The imaging data of 62 patients from Xi'an Xidian Group Hospital,28 patients from Nuclear Industry 215 Hospital of Shanxi Province and 16 patients from Xi'an Gaoxin Hospital with portal vein diseases from January 2012 to March 2015 were retrospectively analyzed.The CT findings,primary and secondary diseases of portal vein lesions were recorded through plain scan and enhanced scan of MSCT.Results Changes in the width of portal vein:among 106 patients,dilation of main portal vein was detected in 45 cases,stenosis of stem or branches of portal vein in 39 cases,portal vein obstruction in 49 cases (21 patients accompanied with enlargement in stem of portal vein and 6 patients with normal width).The diameters of dilated portal vein were 1.4-2.2 cm with a mean diameter of 1.8 cm.The diameters of portal vein with stenosis and occlusion caused by carcinomas were 1.8-4.0 cm with a mean diameter of 2.3cm.Portal vein fistula and pneumatosis:hepatic artery-portal vein fistulas were detected in 12 patients,posterior right branches of portal vein-inferior vena cava fistulas in 2 patients,inferior vena cavaportal vein fistulas and portal-hepatic vein fistulas in 2 patients,pneumatosis in 2 patients.Lesions of portal vein occlusions:occlusions located at main portal veins were detected in 4 cases

  12. Development of a compact high resolution gamma-ray detector for E-CT applications

    Institute of Scientific and Technical Information of China (English)

    ZHU Jie; MA Hongguang; MA Wenyan; ZENG Hui; WANG Zhaomin; XU Zizhong

    2007-01-01

    A compact gamma-ray detector with good spatial resolution for emission computed tomography (E-CT) applications has been developed. The detector is composed of NaI(T1) scintillation pixels array and Hamamastu R2486-05 PSPMT. Having a pixel size of 2 mm × 2 mm and an overall dimension of 48.2 mm × 48.2mm × 5 mm, it has 484 pixels in a 22×22 matrix. An average spatial resolution of 2.5mm (FWHM) was achieved. The slope of position linearity is constant within 10% in a range of 40mm. After corrections, the average value of differential non-linearity and absolute non-linearity were 0.16mm and 0.535mm respectively, and a 17% at FWHM of total energy resolution for 241Am was obtained.

  13. CT 灌注成像联合 CT 血管造影在短暂性脑缺血发作中的应用%CT Perfusion Imaging Combined with CT Angiography in the Application of the Transient Ischemic Attack

    Institute of Scientific and Technical Information of China (English)

    钱树森; 李文波; 林伟; 唐康宁

    2014-01-01

    目的:探讨短暂性脑缺血发作(TIA)CT 灌注成像及 CT 血管造影的特点。方法分析符合标准的40例患者 CT 灌注成像及 CT 血管造影资料。结果患侧 MTT 高于镜像区,CBF 低于镜像区,差异均有统计学意义(P 0.05)。Ⅰ期患者 MTT 低于Ⅱ期,CBF 高于Ⅱ期,差异均存在统计学意义(P 0.05)。 CT 血管造影显示责任血管狭窄31例,其中 CT 灌注成像异常27例,阳性率87.10%;CT 血管造影显示责任血管无狭窄9例,其中 CT 灌注成像异常3例,阳性率33.33%;二者差异有统计学意义(P 0. 05). The MTT of stage I pa-tients were lower than stage II, the CBF were higher than that of stage II, which suggested statistically significant (P 0. 05). CT angiography showed 31 cases responsible angio-stegnosis ; 27 cases of them showed abnormal CT perfusion imaging, the positive rate was 87. 10% ;CT angiography showed 9 cases responsible blood vessels without narrow, 3 cased of them CT perfusion imaging abnormal , the positive rate was 33. 33% ;which suggested significant difference (P < 0. 05). Conclusion CT perfusion imaging can be used to evaluate TIA patients’ he-modynamic changes, combined with head and neck CT angiography, which has important clinical value for TIA’s etiology diagnosis and condition assessment, worthy of clinical popularization and application.

  14. Values of multi-slice spiral computed tomography on predicting hypovolemic shock in patients with severe multiple trauma%多层螺旋CT对严重多发伤患者低血容量性休克的预测价值

    Institute of Scientific and Technical Information of China (English)

    李阳; 张连阳; 王毅; 张伟国

    2013-01-01

    Objective To investigate the value of multi-slice spiral computed tomography (MSCT) on predicting hypovolemic shock in patients with severe multiple trauma. Methods The clinical and MSCT data of 63 patients with severe multiple trauma admitted to the Trauma Center from Jan. 2008 to Dec. 2011 were retrospectively reviewed. According to the occurrence of hypovolemic shock in 24 hours after CT scan, the patients were divided into shock group (n=34) and stable group (n=29). Blood pressure, heart rate, shock index and injury severity score (ISS) on admission were collected and analyzed. Transverse (T) and anteroposterior (AP) diameter of inferior vena cava (IVC), diameter of abdominal aorta, CT values of enhanced CT of abdominal organs both in early and late phase were measured. The differences of aforementioned parameters between the two groups were compared by Student's t test. The values of above indexes showing significant difference between the two groups on predicting hypovolemic shock were analyzed by using receiver operating characteristic (ROC) curve and logistic regression analysis. Results The shock index, ISS and collapsibility index (T/AP) of IVC in 4 abdominal levels were significantly greater in shock group than in stable group (I'<0.05). In early phase of enhanced CT, the mean CT value of spleen was significantly lower in shock group (93 ± 16HU) than in stable group (112 ± 24HU, P<0.0l), while the mean CT value of adrenal gland was higher in shock group (153 ± 35HU) than in stable group (131 ± 24HU, P<0.0l). In delayed phase, the mean CT value of renal medulla was significantly lower in shock group (193 ± 57HU) than in stable group (228 ± S3HU, P<0.05). The diagnostic cutoff value of ROC curve of shock index, ISS, collapsibility index (T/AP) of IVC, CT value of spleen and adrenal gland in early phase, CT value of renal medulla in delayed phase were 1.19, 19.5, 3.02, 115HU, 150HU and 184HU, respectively. Logistic regression analysis showed that ISS

  15. Value and clinical application of orthopedic metal artifact reduction algorithm in CT scans after orthopedic metal implantation

    Energy Technology Data Exchange (ETDEWEB)

    Hu, Yi; Pan, Shinong; Zhao, Xudong; Guo, Wenli; He, Ming; Guo, Qiyong [Shengjing Hospital of China Medical University, Shenyang (China)

    2017-06-15

    To evaluate orthopedic metal artifact reduction algorithm (O-MAR) in CT orthopedic metal artifact reduction at different tube voltages, identify an appropriate low tube voltage for clinical practice, and investigate its clinical application. The institutional ethical committee approved all the animal procedures. A stainless-steel plate and four screws were implanted into the femurs of three Japanese white rabbits. Preoperative CT was performed at 120 kVp without O-MAR reconstruction, and postoperative CT was performed at 80–140 kVp with O-MAR. Muscular CT attenuation, artifact index (AI) and signal-to-noise ratio (SNR) were compared between preoperative and postoperative images (unpaired t test), between paired O-MAR and non-O-MAR images (paired Student t test) and among different kVp settings (repeated measures ANOVA). Artifacts' severity, muscular homogeneity, visibility of inter-muscular space and definition of bony structures were subjectively evaluated and compared (Wilcoxon rank-sum test). In the clinical study, 20 patients undertook CT scan at low kVp with O-MAR with informed consent. The diagnostic satisfaction of clinical images was subjectively assessed. Animal experiments showed that the use of O-MAR resulted in accurate CT attenuation, lower AI, better SNR, and higher subjective scores (p < 0.010) at all tube voltages. O-MAR images at 100 kVp had almost the same AI and SNR as non-O-MAR images at 140 kVp. All O-MAR images were scored ≥ 3. In addition, 95% of clinical CT images performed at 100 kVp were considered satisfactory. O-MAR can effectively reduce orthopedic metal artifacts at different tube voltages, and facilitates low-tube-voltage CT for patients with orthopedic metal implants.

  16. Contrast-enhanced CT- and MRI-based perfusion assessment for pulmonary diseases: basics and clinical applications.

    Science.gov (United States)

    Ohno, Yoshiharu; Koyama, Hisanobu; Lee, Ho Yun; Miura, Sachiko; Yoshikawa, Takeshi; Sugimura, Kazuro

    2016-01-01

    Assessment of regional pulmonary perfusion as well as nodule and tumor perfusions in various pulmonary diseases are currently performed by means of nuclear medicine studies requiring radioactive macroaggregates, dual-energy computed tomography (CT), and dynamic first-pass contrast-enhanced perfusion CT techniques and unenhanced and dynamic first-pass contrast enhanced perfusion magnetic resonance imaging (MRI), as well as time-resolved three-dimensional or four-dimensional contrast-enhanced magnetic resonance angiography (MRA). Perfusion scintigraphy, single-photon emission tomography (SPECT) and SPECT fused with CT have been established as clinically available scintigraphic methods; however, they are limited by perfusion information with poor spatial resolution and other shortcomings. Although positron emission tomography with 15O water can measure absolute pulmonary perfusion, it requires a cyclotron for generation of a tracer with an extremely short half-life (2 min), and can only be performed for academic purposes. Therefore, clinicians are concentrating their efforts on the application of CT-based and MRI-based quantitative and qualitative perfusion assessment to various pulmonary diseases. This review article covers 1) the basics of dual-energy CT and dynamic first-pass contrast-enhanced perfusion CT techniques, 2) the basics of time-resolved contrast-enhanced MRA and dynamic first-pass contrast-enhanced perfusion MRI, and 3) clinical applications of contrast-enhanced CT- and MRI-based perfusion assessment for patients with pulmonary nodule, lung cancer, and pulmonary vascular diseases. We believe that these new techniques can be useful in routine clinical practice for not only thoracic oncology patients, but also patients with different pulmonary vascular diseases.

  17. TU-AB-204-00: Advances in Cone-Beam CT and Emerging Applications

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2015-06-15

    This symposium highlights advanced cone-beam CT (CBCT) technologies in four areas of emerging application in diagnostic imaging and image-guided interventions. Each area includes research that extends the spatial, temporal, and/or contrast resolution characteristics of CBCT beyond conventional limits through advances in scanner technology, acquisition protocols, and 3D image reconstruction techniques. Dr. G. Chen (University of Wisconsin) will present on the topic: Advances in C-arm CBCT for Brain Perfusion Imaging. Stroke is a leading cause of death and disability, and a fraction of people having an acute ischemic stroke are suitable candidates for endovascular therapy. Critical factors that affect both the likelihood of successful revascularization and good clinical outcome are: 1) the time between stroke onset and revascularization; and 2) the ability to distinguish patients who have a small volume of irreversibly injured brain (ischemic core) and a large volume of ischemic but salvageable brain (penumbra) from patients with a large ischemic core and little or no penumbra. Therefore, “time is brain” in the care of the stroke patients. C-arm CBCT systems widely available in angiography suites have the potential to generate non-contrast-enhanced CBCT images to exclude the presence of hemorrhage, time-resolved CBCT angiography to evaluate the site of occlusion and collaterals, and CBCT perfusion parametric images to assess the extent of the ischemic core and penumbra, thereby fulfilling the imaging requirements of a “one-stop-shop” in the angiography suite to reduce the time between onset and revascularization therapy. The challenges and opportunities to advance CBCT technology to fully enable the one-stop-shop C-arm CBCT platform for brain imaging will be discussed. Dr. R. Fahrig (Stanford University) will present on the topic: Advances in C-arm CBCT for Cardiac Interventions. With the goal of providing functional information during cardiac interventions

  18. PET-CT工作原理及应用%Principle and application of PET-CT

    Institute of Scientific and Technical Information of China (English)

    张秀文; 张永寿; 刘乃智

    2012-01-01

    Objective: PET-CT is to use to achieve image fusion of PET and CT in the same machine, is functional imaging equipment. With the rapid spread of its application, it goes beyond the existing areas of PET alone and separate CT for medical research and clinical diagnostics, it provides a great convenience. Methods: PET is deferent with CT in the imaging principle, the combination of these two equipment can get the image of anatomical structure, abundant physiological and biochemical functions. It can provide the quantitative, qualitative diagnostic basis for the identify and locate the precise location of tumors. Results: PET-CT fusion images can be used to describe the role of disease on the biochemical processes, identify physiological and pathological uptake. It can detect the early onset of signs of disease anatomical evidence and even very small subclinical tumor correctly. It has an important value in determining the clinical radiotherapy planning target volume, the detection process of treatment drugs and radiation effects to provide the best treatment options to improve the clinical cure rate. Conclusion: The work is in good condition or not determines by the maintenance. Firstly we should clear the equipment requirements of the environment in the process of routine maintenance carefully. Maintain equipment environment requires qualified engineering and technical personnel familiar with every aspect of the usually diligent maintenance, did not miss any possible hazards to more good to ensure that the operation of the equipment.%目的:PET-CT实现了同机图像融合,是一种功能性医学影像学设备,通过了解其工作原理,掌握设备的日常维护方法,为医学研究和临床诊断提供便利.方法:分别介绍PET与CT两种设备同机组合的不同成像原理以及设备应用时对环境的要求.结果:了解PET-CT的工作原理,掌握一般维护保养项目和方法,使PET-CT融合影像为临床正确确定放疗的计划靶区、

  19. Simple omental diaphragmatic hernia: the diagnosic value of multiplanar reformation in multi-slice spiral CT examination%MSCT多平面重组诊断单纯性横膈网膜疝

    Institute of Scientific and Technical Information of China (English)

    毛齐心; 曹和涛

    2014-01-01

    目的 探讨MSCT多平面重组(multiple planar reconstruction,MPR)诊断单纯性横膈网膜疝(simple omental diaphragmatic hernia,SODH)的价值.方法 31例SODH均行MSCT容积扫描并作亚毫米重组,3名不知手术结果的高年资医师回顾性分析横断位和MPR图像,以发现膈肌中断缺损、膈上脂肪疝囊、“狭颈征”及“阳性血管征”作为诊断SODH依据;横断位及MPR征象显示及诊断差异采用x2检验.结果 31例SODH中Bochdalek疝15例、Morgagni疝4例、医源性膈疝3例、食管裂孔疝6例及腔静脉裂孔疝3例,膈肌中断缺损、膈上疝囊、“狭颈征”及“阳性血管征”横轴位和MPR依次分别显示:6例和22例(x2=16.67,P<0.01)、31例和31例、6例和28例(x2=31.52,P<0.01)及3例和11例(x2 =5.90,P<0.05).横轴位诊断12例,MPR全部明确诊断(x2 =27.40,P<0.01).结论 MSCT MPR清晰显示SODH多种特征性征象,对诊断具有决定意义.

  20. 多层螺旋CT诊断梗阻性黄疸的临床价值%Clinical value of multi-slice spiral CT in the diagnosis of obstructive jaundice

    Institute of Scientific and Technical Information of China (English)

    李希波; 袁有仪; 古育芳

    2014-01-01

    目的 探讨多层螺旋CT诊断梗阻性黄疸的临床价值.方法 收集由手术病理或ERCP证实为143例梗阻性黄疸患者的影像资料,包括螺旋CT平扫和增强扫描、MPR及CPR技术重建图像等.根据术前影像诊断的结果将疾病类型分为良性病变组、恶性病变组,对梗阻部位及性质进行分析,并与手术病理对照.结果 多层螺旋CT定位诊断准确率为100.0%;定性诊断准确率:良性病变组为96.70%,恶性病变组为94.23%.结论 多层螺旋CT对梗阻性黄疸的病变显示清晰,结合增强扫描、MPR、CPR等图像后处理,能直观、立体地显示胆管梗阻的部位、程度以及病变所累及的范围和程度,对梗阻部位和性质的诊断有较高的临床价值.

  1. 多层螺旋CT肠道造影在诊断克罗恩病中的应用%Multi-slice CT in the diagnosis of Crohn's disease

    Institute of Scientific and Technical Information of China (English)

    赵庆玲

    2016-01-01

    克罗恩病(Crohn's disease,CD)为一种终身性疾病,大部分患者常反复发病,严重影响着患者的生活质量.现在主要以临床表现、影像学、内镜以及病理组织学的综合判断作为诊断该病的方法.多层螺旋CT肠道造影(Computed Tomographic Enterography,CTE)为近年来新兴的一种影像学检查方法,因其时间及空间分辨率高,检查速度快、价格适宜等优点而发挥着特异的诊断价值,本文就CTE在克罗恩病中的诊断价值进行综述.

  2. 多层螺旋CT甲状腺体积测量的可重复性评价%THE REPRODUCIBILITY OF THYROID GLAND VOLUMETRY USING MULTI-SLICE SPIRAL CT

    Institute of Scientific and Technical Information of China (English)

    叶述良; 虞德才; 罗锦红; 张昭全

    2009-01-01

    目的:评价多层螺旋CT甲状腺体积测量的可重复性和一致性.方法:25例颈部螺旋CT扫描患者,扫描数据传输至工作站进行甲状腺体积重建、测量.3位有经验的放射科医生独立进行,每位观察者对所有患者均测量两次.观察者内的差异用配对t检验进行比较,观察者间的差异用重复测量的方差分析比较,相互关系用组内相关系数(intraclass correlation coefficient,ICC)描述,P<0.05为有统计学意义.结果:观察者1两次测得甲状腺平均体积为(12.11±5.42)cm3和(12.04_+5.43)cm3.t=1.664,P=0.109,ICC=0.9992,P=0.00.观察者2两次测量的平均体积为(12.09±5.45)cm3和(12.07±5.43)cm3.t=0.445,P=0.661,ICC=0.9991,P=0.00.观察者3两次测量的平均体积为(12.09±5.42)cm3和(12.16±5.46)cm3.t=1.282,P=0.212,ICC=0.9989,P=0.00.3个观察者所测体积的均值分别是(12.07±5.42)cm3、(12.08±5.44)cm3和(12.12±5.44)cm3.F=1.556,P=0.222,ICC=0.9996,P=0.00.结论:螺旋CT甲状腺体积测量具有较高的可重复性和一致性.

  3. 健康体检中多层螺旋CT冠脉成像的初步观察%Initial observations of multi-slice spiral CT coronary angiography (CTCA) in health examination

    Institute of Scientific and Technical Information of China (English)

    薛祖平; 黄吟华; 陈斌; 林银虎; 周卫平; 张洁; 蒋磊; 田国才; 左翔; 黄海峡; 潘祖军; 吴建彬; 吴科峰

    2010-01-01

    目的 探讨健康体检中多层螺旋CT冠脉成像(CTCA)对冠脉病变的价值.方法 对随机抽取的289例健康体检时进行CTCA的病例作冠脉钙化(CAC)的定性分析,然后分别对CAC阴性者和CAC阳性者的冠脉狭窄情况进行统计分析.结果 289名受检者中77例为CAC阳性,占26.64%;212例为CAC阴性,占73.36%.在CAC阳性者中检出冠脉狭窄57例,占74.03%;CAC阴性者中检出冠脉狭窄21例,占9.91%.结论 在健康体检时行胸部CT检查发现CAC阳性者,均应做CTCA检查;对CAC阴性者,如有高血糖、高血压、高血脂、吸烟者或有胸闷史者,也应做CTCA检查,以明确有无非钙化斑块的存在,避免非钙化斑块的漏诊.

  4. The Value of Multi-slice Spiral CT in the Diagnosis of Gallstone Ileus%多层螺旋CT在胆石性肠梗阻诊断中的价值

    Institute of Scientific and Technical Information of China (English)

    孙东辉; 张继扬; 万业达; 许相丰; 何岸苇; 张琳

    2010-01-01

    目的 探讨多层螺旋CT在胆石性肠梗阻诊断中的价值.方法 回顾分析15例经手术证实的胆石性肠梗阻病例的临床及影像资料.15例均行全腹部CT平扫、X线腹部平片和腹部超声检查.结果 多层螺旋CT显示肠梗阻共15例,不完全性小肠梗阻12例,完全性肠梗阻3例;异位结石15例,其中9例位于回肠,4例位于空肠, 1例于胆囊内及回肠内均可见结石,1例于胆囊-十二指肠瘘口及回肠内各见一结石;胆囊积气15例,胆道积气13例;胆囊窝结构紊乱15例,其中6例MPR图像清晰显示胆囊-十二指肠瘘.多层螺旋CT的诊断准确率可达100%.结论 多层螺旋CT在胆石性肠梗阻的定位和定性诊断中具有重要价值,为手术方案的制订提供影像学信息.

  5. Performance evaluation of a compact PET/SPECT/CT tri-modality system for small animal imaging applications

    Energy Technology Data Exchange (ETDEWEB)

    Wei, Qingyang [Department of Electrical Engineering, Tsinghua University, Beijing 100084 (China); Key Laboratory of Particle & Radiation Imaging (Tsinghua University), Ministry of Education, Beijing 100084 (China); Wang, Shi [Department of Engineering Physics, Tsinghua University, Beijing 100084 (China); Key Laboratory of Particle & Radiation Imaging (Tsinghua University), Ministry of Education, Beijing 100084 (China); Ma, Tianyu, E-mail: maty@tsinghua.edu.cn [Department of Engineering Physics, Tsinghua University, Beijing 100084 (China); Key Laboratory of Particle & Radiation Imaging (Tsinghua University), Ministry of Education, Beijing 100084 (China); Wu, Jing; Liu, Hui; Xu, Tianpeng; Xia, Yan; Fan, Peng; Lyu, Zhenlei; Liu, Yaqiang [Department of Engineering Physics, Tsinghua University, Beijing 100084 (China); Key Laboratory of Particle & Radiation Imaging (Tsinghua University), Ministry of Education, Beijing 100084 (China)

    2015-06-21

    PET, SPECT and CT imaging techniques are widely used in preclinical small animal imaging applications. In this paper, we present a compact small animal PET/SPECT/CT tri-modality system. A dual-functional, shared detector design is implemented which enables PET and SPECT imaging with a same LYSO ring detector. A multi-pinhole collimator is mounted on the system and inserted into the detector ring in SPECT imaging mode. A cone-beam CT consisting of a micro focus X-ray tube and a CMOS detector is implemented. The detailed design and the performance evaluations are reported in this paper. In PET imaging mode, the measured NEMA based spatial resolution is 2.12 mm (FWHM), and the sensitivity at the central field of view (CFOV) is 3.2%. The FOV size is 50 mm (∅)×100 mm (L). The SPECT has a spatial resolution of 1.32 mm (FWHM) and an average sensitivity of 0.031% at the center axial, and a 30 mm (∅)×90 mm (L) FOV. The CT spatial resolution is 8.32 lp/mm @10%MTF, and the contrast discrimination function value is 2.06% with 1.5 mm size cubic box object. In conclusion, a compact, tri-modality PET/SPECT/CT system was successfully built with low cost and high performance.

  6. A three-dimensional reconstruction of the temporal bone by the helical scanning CT and its clinical application

    Energy Technology Data Exchange (ETDEWEB)

    Yonekawa, Hiroyuki; Ohashi, Masami; Miyashita, Souji; Gotoh, Mizuho; Nemoto, Satohiko; Kikuchi, Hideki (Azabu Triology Hospital, Sapporo (Japan)); Sakai, Noboru; Inuyama, Yukio

    1993-09-01

    The current availability of 3 dimensional (3-D) imaging from Computed Tomography (CT) has yielded new anatomical information and pre- and postoperative evaluations. However, little discussion as to the 3-D structural image of the temporal bone has been reported because conventional CT does provide sufficient data to produce such images. The helical scanning CT gathers continuous and multiple slice image data since it consists of an X-ray tube that continuously rotates around the patient while the patient moves continuously into the CT scanner. Thus, application of the helical scanning CT has made it possible to reconstruct 3-D images of the minute and complicated structure of the temporal bone. We evaluated 3-D images from 9 typical cases, examined from February to October 1992. As a result, we found that the 3-D images reconstructed with this system are useful for evaluation of the postoperative state of tympanoplasty, the diagnosis of anomalies of the bony labyrinth, and examining the extent of bone destruction induced by trauma, cholesteatoma, etc. (author).

  7. Multi-slice computed tomography imaging anatomy study of adrenal vein%肾上腺静脉MSCT影像解剖研究

    Institute of Scientific and Technical Information of China (English)

    李晓燕; 吕发金; 周永霞; 张翱; 胡良波; 刘丹

    2015-01-01

    目的:利用MSCT准确显示肾上腺静脉正常解剖结构及变异,为临床提供影像解剖数据。方法回顾分析上腹部CTA患者108例。薄层MIP/MPR评估测量肾上腺静脉管径、长度及走行路径。结果①右侧:显示率64.81%(70/108),变异5.71%(4/70);汇入下腔静脉7点至8点间占优势42.42%;其管径Rr (2.19±0.56) mm,腺外段长度RD1(5.02±1.82) mm,汇入下腔静脉距右肾静脉汇入距离RD2(40.69±12.96) mm,汇入口开口向下角度RA (60.25±17.85)°。②左侧:显示率97.22%(105/108);变异14.29%(15/105);肾上腺静脉管径Lr (2.39±0.56) mm,腺外段长度LD1(7.28±4.01) mm,膈-肾上腺静脉干管径LR (3.65±0.93) mm,膈-肾上腺静脉的共干段长度LD2(14.07±6.77) mm,膈-肾上腺静脉汇入左肾静脉点至下腔静脉左侧缘距离LD3(32.89±4.85) mm,膈-肾上腺静脉汇入左肾静脉开口向内的角度LA1(118.06±18.49)°,肾上腺静脉与膈静脉共干段开口向下的角度LA2(156.15±13.81)°。结论 MSCT可显示大部分右侧肾上腺静脉及绝大部分左侧肾上腺静脉正常走行及变异,测量相关影像解剖数据,为AVS等手术方案提供影像数据。%Objective Using MSCT to display the normal anatomic structure and variation of the adrenal vein accurately and to provide image anatomy data for clinical application. Methods 108 patients with abdominal examination of CTA were retrospectively analyzed. A thin layer of MIP and MPR technique was applied to evaluate and measure the adrenal vein diameter, length and line path. Results ① Display rate and variation rate in the right side was 64.81% (70/108) and 5.71% (4/70). The adrenal vein drained directly into the inferior vena cava in 7 o'clock to 8 o'clock direction, accounting for a majority of 42.42%(28/66). The diameter of adrenal vein was (2.19±0.56) mm, the length of vein outside the gland was (15.02± 1.82) mm, the distance between the sites where the

  8. Inter-laboratory comparison of medical computed tomography (CT) scanners for industrial applications in the slaughterhouses

    DEFF Research Database (Denmark)

    Christensen, Lars Bager; Angel, Jais Andreas Breusch

    2013-01-01

    differences in CT performance. The presented Round Robin scheme has demonstrated its potential as such a method. The benefit of the phantom set is that it provides a convenient way of comparing volume determination between different CT scanners. The suggested phantoms are mimicking important carcass features...

  9. The clinical application of combined dualenergy CT pulmonary angiography and indirect venography

    Institute of Scientific and Technical Information of China (English)

    富青

    2013-01-01

    Objective To assess the usefulness of combined dual-energy CT pulmonary angiography (DE-CTPA) and indirect CT venography(CTV) in the diagnosis of venous thromboembolism(VTE). Methods Forty-nine patients with leg swelling suspected of pulmonary embolism(PE) underwent both DE-CTPA combined with CTV and lower

  10. 急性下消化道穿孔的 MSCT 诊断%CT diagnosis of acute lower gastrointestinal perforation

    Institute of Scientific and Technical Information of China (English)

    叶明; 胡志; 周泉生

    2015-01-01

    目的:分析急性下消化道穿孔的多层螺旋 CT(MSCT)表现,探讨其诊断价值。方法对21例手术证实的急性下消化道穿孔患者的 MSCT 图像进行回顾性分析。结果21例下消化道穿孔的主要 MSCT 表现为腹腔游离气体10例、腹腔积液18例、肠壁节段性增厚14例、肠壁破口3例、穿孔周围气泡征10例、局限性腹膜炎20例、穿孔周围粪块或肠内容物4例。结论MSCT 可直接显示穿孔部位,准确判断游离气液体有无,同时能发现部分穿孔病因、合并症等有价值的信息,对急性下消化道穿孔有较高的临床诊断价值。%Objective To analyze multi-slice spiral CT findings of acute lower gastrointestinal perforation and explore its diagnos-tic value.Methods Multi-slice spiral CT findings of 21 patients with acute lower gastrointestinal perforation proved by surgery were analyzed retrospectively.Results Multi-slice spiral CT manifestations of 21 patients with lower digestive tract perforation were as following:peritoneal free gas in 10 cases,abdominal fluid 18 cases,intestinal segmental wall thickening 14 cases,intestinal wall rupture 3 cases,bubble sign around the perforation 10 cases,local peritonitis 20 cases,peripheral turd or intestinal contents 4 cases. Conclusion Multi-slice CT can directly show the site of perforation,display the accurate judgment of free gas or liquid and find the part of perforation etiology,complications and other valuable information for clinical diagnosis of acute lower digestive tract.

  11. High-concentration contrast media in neurological multidetector-row CT applications: implications for improved patient management in neurology and neurosurgery

    Energy Technology Data Exchange (ETDEWEB)

    Schramm, Peter [University of Heidelberg Medical Center, Department of Neuroradiology, Heidelberg (Germany)

    2007-07-15

    Dynamic CT scanning after intravenous injection of iodine contrast medium (CM) was proposed in the very early days of CT. The goal was to characterize tissue by extracting information from the temporal course of enhancement. In the early 1980s, modeling algorithms were already described in the literature for the quantitative calculation of cerebral blood flow (CBF). However, cerebral applications suffered from the insufficient temporal resolution available at that time and the central nervous system was already seen primarily as an MRI domain. The renaissance of dynamic CT in neurological applications came in the middle of the 1990s with the introduction of thrombolytic therapy in acute stroke. With CT being the primary imaging modality, getting additional hemodynamic information from the same device without having to move the patient appeared attractive. Multimodal CT protocols allow a comprehensive diagnosis of the emergency stroke patient in less than 15 minutes by combining nonenhanced CT (NECT), perfusion CT (PCT) and CT angiography (CTA). Dynamic PCT can also render important information in patients with intraaxial brain tumors, allowing differentiation not only between lymphoma and glioma but also between low-grade and high-grade glioma by quantifying local cerebral blood volume (CBV) and permeability of the blood-brain barrier (BBB). Hoever, even if a shorter imaging time permits a reduction in volume of CM, adequate total iodine levels must be preserved for dynamic CT applications. Increased concentrations of iodine are therefore helpful to obtain adequate total iodine levels for imaging. (orig.)

  12. Musculoskeletal wide detector CT: Principles, techniques and applications in clinical practice and research

    Energy Technology Data Exchange (ETDEWEB)

    Gondim Teixeira, Pedro Augusto, E-mail: ped_gt@hotmail.com [Guilloz Imaging Department, Central Hospital, University Hospital Center of Nancy, 29 avenue du Maréchal de Lattre de Tassigny, 54035 Nancy Cedex (France); Gervaise, Alban [Medical Imaging Department, Legouest Military Instruction Hospital, 27 Avenue de Plantières, BP 90001, 57077 Metz Cedex 3 (France); Louis, Matthias; Lecocq, Sophie; Raymond, Ariane; Aptel, Sabine; Blum, Alain [Guilloz Imaging Department, Central Hospital, University Hospital Center of Nancy, 29 avenue du Maréchal de Lattre de Tassigny, 54035 Nancy Cedex (France)

    2015-05-15

    Highlights: • Wide area-detector CT availability is growing steadily. • Advanced techniques such as Dynamic CT, Perfusion CT and dual energy can be used in clinical practice. • Optimal acquisition protocol is needed to increase diagnostic performance and limit dose exposure. • Guidelines for data acquisition and interpretation may increase diagnostic performance and reproducibility. - Abstract: A progressive increase in the detector width in CT scanners has meant that advanced techniques such as dynamic, perfusion and dual-energy CT are now at the radiologist's disposal. Although these techniques may be important for the diagnosis of various musculoskeletal diseases, data acquisition and interpretation can be challenging. This article offers a practical guide for the use of these tools including acquisition protocol, post-processing options and data interpretation based on 7 years of clinical experience in a tertiary university hospital.

  13. 3D intrathoracic region definition and its application to PET-CT analysis

    Science.gov (United States)

    Cheirsilp, Ronnarit; Bascom, Rebecca; Allen, Thomas W.; Higgins, William E.

    2014-03-01

    Recently developed integrated PET-CT scanners give co-registered multimodal data sets that offer complementary three-dimensional (3D) digital images of the chest. PET (positron emission tomography) imaging gives highly specific functional information of suspect cancer sites, while CT (X-ray computed tomography) gives associated anatomical detail. Because the 3D CT and PET scans generally span the body from the eyes to the knees, accurate definition of the intrathoracic region is vital for focusing attention to the central-chest region. In this way, diagnostically important regions of interest (ROIs), such as central-chest lymph nodes and cancer nodules, can be more efficiently isolated. We propose a method for automatic segmentation of the intrathoracic region from a given co-registered 3D PET-CT study. Using the 3D CT scan as input, the method begins by finding an initial intrathoracic region boundary for a given 2D CT section. Next, active contour analysis, driven by a cost function depending on local image gradient, gradient-direction, and contour shape features, iteratively estimates the contours spanning the intrathoracic region on neighboring 2D CT sections. This process continues until the complete region is defined. We next present an interactive system that employs the segmentation method for focused 3D PET-CT chest image analysis. A validation study over a series of PET-CT studies reveals that the segmentation method gives a Dice index accuracy of less than 98%. In addition, further results demonstrate the utility of the method for focused 3D PET-CT chest image analysis, ROI definition, and visualization.

  14. Three dimensional CT of stapes. Stapedial imagings in dry temporal bone and clinical applications

    Energy Technology Data Exchange (ETDEWEB)

    Edamatsu, Hideo; Kubota, Osamu; Yamashita, Koichi [Kanazawa Medical Univ., Ishikawa (Japan)

    1995-03-01

    This study was performed to evaluate the usefulness and limitations of three dimensional (3-D) imagings of stapes in the middle ear by high speed helical CT. One dissected human temporal bone, ten normal and diseased ears were scanned with a slice of 1.0 mm and reconstructed in a thickness of 0.2-0.5 mm. Every specimen of 3-D can be observed in any plane and from any direction. Ossicular imagings of the temporal bone in 3-D were reconstructed as if the malleus, incus and stapes were observed under microscope. The whole structure of stapes was impossible to be represented by two dimensional CT heretofore in use, but 3-D in our study showed the head, crus and foot plate of the stapes in detail. Stapedial imagings of 3-D CT in normal ears showed the same findings as those recorded in temporal bone. Preoperative diagnostic findings of ossicles in the affected ears were very useful. Especially in ossicular anomalies, 3-D CT was positive in diagnosis and its accuracies were confirmed with operative observation. For the postoperative evaluation concerning the ossicular reconstruction, i.e. TORP and PORP, 3-D CT was also important method. It could present an anatomical relation between those prosthesis and the oval window. High speed helical CT can scan an object more quickly and clearly than formerly used CT, and its biological damage for human is less than that of the others. 3-D CT can be more clearly reconstructed with helical CT than former CT. (author).

  15. [Development of transXend detector and its application to low dose exposure CT].

    Science.gov (United States)

    Kanno, Ikuo

    2013-01-01

    For practical energy-resolved computed tomography (CT), a transXend detector is proposed. The transXend detector consists of several segment detectors which are aligned along the direction of X-ray incidence. With response functions of segment detectors, the energy distribution of incident X-rays is obtained after unfolding process. Because the transXend detector measures X-rays as electric currents, it has no limit of counting rate: the number of X-rays in medical diagnosis ranges 10(6)-10(9)n/mm2/s, measuring energy of each X-ray is not practical at this stage. The operation principle and ways of application of the transXend detector are described. With defining narrow energy ranges in an unfolding process, effective atomic numbers are estimated with using white X-rays: the transXend detector can cut out quasi-monochromatic X-rays out of white X-rays. With the transXend detector with absorbers among the segment detectors, the directions of material thickness increment are shown different in the graph made of electric current ratios measured by the segment detectors. Using the current ratio graph, the thicknesses of the materials along the line X-rays passed are estimated. In other words, cancers marked by contrast agent can be detected with one transmission measurement, and possibly are measured and positioned by transmission measurements from two directions.

  16. SU-E-I-26: The CT Compatibility of a Novel Direction Modulated Brachytherapy (DMBT) Tandem Applicator for Cervical Cancer

    Energy Technology Data Exchange (ETDEWEB)

    Elzibak, A; Safigholi, H; Soliman, A; Ravi, A; Song, WY [Sunnybrook Health Sciences Centre, University of Toronto, Toronto, Ontario (Canada); Kager, P [The Netherlands Cancer Institute, Amsterdam (Netherlands); Han, D [Sunnybrook Health Sciences Centre, University of Toronto, Toronto, Ontario (Canada); University of California, San Diego, La Jolla, CA (United States)

    2015-06-15

    Purpose: To examine CT metal image artifact from a novel direction-modulated brachytherapy (DMBT) tandem applicator (95% tungsten) for cervical cancer using a commercially available orthopedic metal artifact reduction (O-MAR) algorithm. Comparison to a conventional stainless steel applicator is also performed. Methods: Each applicator was placed in a water-filled phantom resembling the female pelvis and scanned in a Philips Brilliance 16-slice CT scanner using two pelvis protocols: a typical clinical protocol (120kVp, 16×0.75mm collimation, 0.692 pitch, 1.0s rotation, 350mm field of view (FOV), 600mAs, 1.5mm slices) and a protocol with a higher kVp and mAs setting useful for larger patients (140kVp, 16×0.75mm collimation, 0.688 pitch, 1.5s rotation, 350mm FOV, 870mAs, 1.5mm slices). Images of each tandem were acquired with and without the application of the O-MAR algorithm. Baseline scans of the phantom (no applicator) were also collected. CT numbers were quantified at distances from 5 to 30 mm away from the applicator’s edge (in increments of 5mm) using measurements at eight angles around the applicator, on three consecutive slices. Results: While the presence of both applicators degraded image quality, the DMBT applicator resulted in larger streaking artifacts and dark areas in the image compared to the stainless steel applicator. Application of the O-MAR algorithm improved all acquired images, both visually and quantitatively. The use of low and high kVp and mAs settings (120 kVp/600mAs and 140 kVp/870mAs) in conjunction with the O-MAR algorithm lead to similar CT numbers in the vicinity of the applicator and a similar reduction of the induced metal artifact. Conclusion: This work indicated that metal artifacts induced by the DMBT and the stainless steel applicator are greatly reduced when using the O-MAR algorithm, leading to better quality phantom images. The use of a high dose protocol provided similar improvements in metal artifacts compared to the

  17. Is the Canadian CT head rule for minor head injury applicable for patients in Germany?; Laesst sich die Canadian CT Head Rule fuer das leichte Schaedel-Hirn-Trauma auf Deutschland uebertragen?

    Energy Technology Data Exchange (ETDEWEB)

    Schlegel, P.M.; Walter, M.A.; Kloska, S.P.; Heindel, W. [Inst. fuer Klinische Radiologie, Universitaetsklinikum Muenster (Germany); Rieger, B.; Wassmann, H. [Klinik und Poliklinik fuer Neurochirurgie, Universitaetsklinikum Muenster (Germany); Fischer, R.J. [Inst. fuer Medizinische Informatik und Biomathematik, Universitaetsklinikum Muenster (Germany)

    2005-06-01

    Purpose: to evaluate the applicability of the Canadian CT head rule (CCHR) on head trauma patients in a German university hospital. Methods: 122 patients (m = 74; f = 48; 40 {+-} 19 years) were examined with cranial CT due to minor head trauma. The need for cranial CT according to the CCHR was evaluated retrospectively. Results: with a sensitivity of 98.9% and a specificity of 46.6% all patients with the need for neurosurgical intervention were detected by applying the major criteria of the CCHR. Also, every patient with severe brain injury was detected by the extended criteria with a sensitivity of 99.6% and a specificity of 34.1%. This would have led to a reduction in the rate of cranial CT examinations by 45.1% for the major and 22.1% for the extended criteria. No patient with severe brain injury would have been missed by application of the criteria. Conclusion: the Canadian CT head rule for patients with minor head trauma is applicable with a very high sensitivity and the potential of significantly reducing the rate of cranial CT examinations in these patients. (orig.)

  18. Application of 64 slice spiral CT in evaluating the patency of coronary artery after stent implantation

    Institute of Scientific and Technical Information of China (English)

    Yong-Shu Gao; Xing-Can Ma

    2015-01-01

    Objective:To explore the feasibility and effectiveness of 64 slice spiral CT in evaluating the patency of coronary artery after stent implantation.Methods:The 64 slice spiral CT image data of 125 patients after coronary artery stent implantation were collected, meanwhile, the image data of 25 patients underwent coronary angiography were also collected. The feasibility and accuracy of 64 slice spiral CT coronary artery stent imaging were comparatively analyzed. Results: The 64 slice spiral CT imaging quality with a stent diameter greater than 3.00 mm was significantly superior to that with a diameter of 2.25-3.00 mm. The CT imaging quality in the left main coronary artery and anterior descending artery was significantly higher than that in the left circumflex coronary artery. The CT imaging quality in the left main coronary artery was significantly higher than that in the right coronary artery. The CT reconstruction imaging quality in the drug coating stent was significantly superior to that in the bare metal stent. The sensitivity of 64 slice spiral CT was 100.00%, and the accuracy was 100.00%. In detecting the coronary artery with occlusion and stenosis (stent stenosis greater than 50%), the sensitivity was 90.00%, the false negative rate was 10.00%, and the positive predicative value was 100.00%.Conclusions:The effect of 64 slice spiral CT coronary imaging in evaluating the patency of coronary artery after stent implantation is highly consistent with that by coronary angiography, with a simple operation, less risk, and low cost, and thus, it can be completely taken as the imaging method in evaluating the patency of coronary artery after stent implantation.

  19. A compressed sensing-based iterative algorithm for CT reconstruction and its possible application to phase contrast imaging

    Directory of Open Access Journals (Sweden)

    Li Xueli

    2011-08-01

    Full Text Available Abstract Background Computed Tomography (CT is a technology that obtains the tomogram of the observed objects. In real-world applications, especially the biomedical applications, lower radiation dose have been constantly pursued. To shorten scanning time and reduce radiation dose, one can decrease X-ray exposure time at each projection view or decrease the number of projections. Until quite recently, the traditional filtered back projection (FBP method has been commonly exploited in CT image reconstruction. Applying the FBP method requires using a large amount of projection data. Especially when the exposure speed is limited by the mechanical characteristic of the imaging facilities, using FBP method may prolong scanning time and cumulate with a high dose of radiation consequently damaging the biological specimens. Methods In this paper, we present a compressed sensing-based (CS-based iterative algorithm for CT reconstruction. The algorithm minimizes the l1-norm of the sparse image as the constraint factor for the iteration procedure. With this method, we can reconstruct images from substantially reduced projection data and reduce the impact of artifacts introduced into the CT reconstructed image by insufficient projection information. Results To validate and evaluate the performance of this CS-base iterative algorithm, we carried out quantitative evaluation studies in imaging of both software Shepp-Logan phantom and real polystyrene sample. The former is completely absorption based and the later is imaged in phase contrast. The results show that the CS-based iterative algorithm can yield images with quality comparable to that obtained with existing FBP and traditional algebraic reconstruction technique (ART algorithms. Discussion Compared with the common reconstruction from 180 projection images, this algorithm completes CT reconstruction from only 60 projection images, cuts the scan time, and maintains the acceptable quality of the

  20. Application of Neutron Bubble Detectors in Neutron Measurements for IPT-15122 Industrial CT

    Institute of Scientific and Technical Information of China (English)

    2008-01-01

    <正>Industrial CT is now widely used for non-destructive testing of large-scale industrial components using the X-ray produced by the reactions between electron beams and target. It is one of the most

  1. Rich internet application system for patient-centric healthcare data management using handheld devices.

    Science.gov (United States)

    Constantinescu, L; Pradana, R; Kim, J; Gong, P; Fulham, Michael; Feng, D

    2009-01-01

    Rich Internet Applications (RIAs) are an emerging software platform that blurs the line between web service and native application, and is a powerful tool for handheld device deployment. By democratizing health data management and widening its availability, this software platform has the potential to revolutionize telemedicine, clinical practice, medical education and information distribution, particularly in rural areas, and to make patient-centric medical computing a reality. In this paper, we propose a telemedicine application that leverages the ability of a mobile RIA platform to transcode, organise and present textual and multimedia data, which are sourced from medical database software. We adopted a web-based approach to communicate, in real-time, with an established hospital information system via a custom RIA. The proposed solution allows communication between handheld devices and a hospital information system for media streaming with support for real-time encryption, on any RIA enabled platform. We demonstrate our prototype's ability to securely and rapidly access, without installation requirements, medical data ranging from simple textual records to multi-slice PET-CT images and maximum intensity (MIP) projections.

  2. Examination of image information on dental application. Extraction and significance of CT values for the teeth

    Energy Technology Data Exchange (ETDEWEB)

    Handa, Kazuko

    1988-06-01

    The first molar tooth of the mandibule from 11 volunteers was used to determine computed tomography (CT) values in the enamel, dentine, cement, pulp cavity, and root canal. Peak CT values were 1776 for the enamel, 1525 for the dentine, 1342 for the cement, 1275 for the pulp cavity, and 1318 for the root canal. Average CT values were 1730 for the enamel, 1461 for the dentine, 1305 for the cement, 1290 for the pulp cavity, and 1297 for the root canal. When calculating CT values from 10 longitudinal images and 10 or more transverse images, the values were 1843 for the enamel, 1516 for the dentine, 1292 for the cement, 942 for the pulp cavity, and 1116 for the root canal. Ten-slice images provided more definitive discrimination of the test materials when compared with peak and average CT values. Three-dimensional CT images in 10 slices may provide visual demonstration of each tissue in the teeth. (Namekawa, K.) 61 refs.

  3. Comparative analysis of multi-slice computer tomography enterography (MSCTE) and digestive endoscopy on the involved site of Crohn disease%MSCTE与消化内镜检查发现Crohn病累及部位的比较分析

    Institute of Scientific and Technical Information of China (English)

    张燕红; 叶文卫; 陈毅斌; 张锡迎; 杨宇峰; 刘琴

    2016-01-01

    目的:探讨多层螺旋CT口服小肠造影(MSCTE)与消化内镜检查发现Crohn病累及部位的临床价值。方法选取两家医院临床随访证实为 Crohn 病患者30例,行消化内镜检查为 A组,行MSCTE检查为B组,A、B两组发现Crohn病累及部位进行比较分析。结果 A组无异常6例,累及单独小肠5例,小肠及结直肠10例,单独结直肠9例;B组累及单独小肠14例,小肠及结直肠9例,单独结直肠7例。A、B两组发现Crohn病累及部位的比较有统计学意义(P<0.05)。结论 MSCTE诊断Crohn病累及部位较消化内镜具有更高的临床价值。%ObjectiveThe aim of the present study was to evaluate the clinical value of multi-slice computer tomography enterography (MSCTE) and digestive endoscopy on the involved site of Crohn disease(CD).MethodsSelected 30 patients with CD from two hospitals confirmed by clinical follow-up. Digestive endoscopy as group A, MSCTE examination as group B, involved site of two groups of CD were compared and analyzed.ResultsIn group A, 6 cases had been found normal, 5 cases had been found that lesion site was in the small intestine, 10 cases in the small intestine and colorectal, 9 cases only in the colorectal. In group B, 14 cases had been found the lesion site was in the small intestine only, 9 cases in the small intestine and colorectal, 7 cases in the colorectal only. There had statistical significance between group A and group B (P<0.05).ConclusionThe MSCTE has higher clinical value to diagnose the involved site of CD.

  4. Deformable 3D-2D registration for CT and its application to low dose tomographic fluoroscopy

    Science.gov (United States)

    Flach, Barbara; Brehm, Marcus; Sawall, Stefan; Kachelrieß, Marc

    2014-12-01

    Many applications in medical imaging include image registration for matching of images from the same or different modalities. In the case of full data sampling, the respective reconstructed images are usually of such a good image quality that standard deformable volume-to-volume (3D-3D) registration approaches can be applied. But research in temporal-correlated image reconstruction and dose reductions increases the number of cases where rawdata are available from only few projection angles. Here, deteriorated image quality leads to non-acceptable deformable volume-to-volume registration results. Therefore a registration approach is required that is robust against a decreasing number of projections defining the target position. We propose a deformable volume-to-rawdata (3D-2D) registration method that aims at finding a displacement vector field maximizing the alignment of a CT volume and the acquired rawdata based on the sum of squared differences in rawdata domain. The registration is constrained by a regularization term in accordance with a fluid-based diffusion. Both cost function components, the rawdata fidelity and the regularization term, are optimized in an alternating manner. The matching criterion is optimized by a conjugate gradient descent for nonlinear functions, while the regularization is realized by convolution of the vector fields with Gaussian kernels. We validate the proposed method and compare it to the demons algorithm, a well-known 3D-3D registration method. The comparison is done for a range of 4-60 target projections using datasets from low dose tomographic fluoroscopy as an application example. The results show a high correlation to the ground truth target position without introducing artifacts even in the case of very few projections. In particular the matching in the rawdata domain is improved compared to the 3D-3D registration for the investigated range. The proposed volume-to-rawdata registration increases the robustness regarding sparse

  5. TC multicorte (TCMC cardiaca: aplicaciones clínicas Multislice CT of the heart: clinical applications

    Directory of Open Access Journals (Sweden)

    G. Bastarrika

    2004-04-01

    Full Text Available La introducción de los equipos de TC multicorte y el desarrollo de técnicas de adquisición de imágenes con sincronización electrocardiográfica y reconstrucción retrospectiva han permitido que la TC multicorte cardiaca se pueda considerar hoy en día una técnica no invasiva muy útil para el estudio de la patología cardiaca en la práctica clínica diaria. La valoración de las arterias coronarias es una de las principales aplicaciones clínicas de esta técnica diagnóstica e incluye la detección y cuantificación del calcio coronario, la coronariografía por TC multicorte (estudio de la anatomía coronaria, variantes anatómicas y anomalías del origen y trayecto, la valoración angiográfica de la permeabilidad de injertos aortocoronarios y endoprótesis vasculares y la caracterización de las placas de ateroma. Los nuevos programas de reconstrucción y postprocesamiento permiten obtener, además, parámetros de morfología y contracción miocárdica y función cardiaca. Otras aplicaciones clínicas incluyen la caracterización de masas cardiacas intracavitarias y la valoración del pericardio.Since the introduction of last generation multislice MSCT systems and the development of simultaneous electrocardiographic-tracing image acquisition and retrospective reconstruction techniques into clinical routine, cardiac MSCT has been considered a very useful non-invasive technique for the study of cardiac pathology in the daily clinical practice. One of the main clinical applications of this diagnostic technique is the evaluation of the coronary arteries including detection and quantification of coronary calcium, multislice CT coronary angiography (anatomy, anatomical variants and anomalies of the origin and course, the angiographic evaluation of the patency of aortocoronary by-pass grafts and coronary stents, and plaque characterization. The new reconstruction and postprocessing programs allow to obtain, in addition, parameters of

  6. Application of microCT to the non-destructive testing of an additive manufactured titanium component

    Directory of Open Access Journals (Sweden)

    Anton du Plessis

    2015-11-01

    Full Text Available In this paper the application of X-ray microCT to the non-destructive testing of an additive manufactured titanium alloy component of complex geometry is demonstrated. Additive manufacturing of metal components is fast growing and shows great promise, yet these parts may contain defects which affect mechanical properties of the components. In this work a layered form of defect is found by microCT, which would have been very difficult or impossible to detect by other non-destructive testing methods due to the object complexity, defect size and shape and because the pores are entirely contained inside the object and not connected to the surface. Additionally, this test part was subjected to hot isostatic pressing (HIPPING and subsequently scanned. Comparing before and after scans by alignment of the volumes allows visualization and quantification of the pore size changes. The application of X-ray microCT to additive manufacturing is thus demonstrated in this example to be an ideal combination, especially for process improvements and for high value components.

  7. Daily CT measurement of needle applicator displacement during multifractionated high-dose-rate interstitial brachytherapy for postoperative recurrent uterine cancer.

    Science.gov (United States)

    Yoshida, Ken; Ueda, Mari; Takenaka, Tadashi; Yamazaki, Hideya; Kotsuma, Tadayuki; Aramoto, Kazumasa; Miyake, Shunsuke; Koretsune, Yukihiro; Ban, Chiaki; Tanaka, Eiichi

    2012-01-01

    We investigated daily needle applicator displacement during multifractionated high-dose-rate interstitial brachytherapy (HDR-ISBT) for postoperative recurrent uterine cancer. Eight patients with postoperative recurrent uterine cancer received HDR-ISBT with or without external beam radiotherapy using our unique ambulatory technique. To analyze displacement, we obtained daily computed tomography (CT) images for 122 flexible needle applicators at 21, 45, 69, and 93 hours after implantation. Displacement was defined as the length between the center of gravity of titanium markers and the needle applicator tips along the daily CT axis. For cases in which displacement was not corrected, we also calculated the dose that covered 90% of the clinical target volume (D90(CTV)) using a dose-volume histogram (DVH). Median caudal needle applicator displacement at 21, 45, 69, and 93 hours was 3, 2, 4, and 5 mm, respectively. More than 15 mm displacement was observed for 2% (2 of 122) and 17% (10 of 60) of needle applicators at 21 and 93 hours, respectively. Cases in which dwell positions were not changed to correct the treatment plan, 2 of 8 patients showed more than 10% reduction in D90(CTV) values compared with the initial treatment plan. Correction of dwell positions of the treatment source improves treatment DVH for multifractionated HDR-ISBT.

  8. Clinical application of lower extremity CTA and lower extremity perfusion CT as a method of diagnostic for lower extremity atherosclerotic obliterans

    Energy Technology Data Exchange (ETDEWEB)

    Moon, Il Bong; Dong, Kyung Rae [Dept. Radiological Technology, Gwangju Health University, Gwangju (Korea, Republic of); Goo, Eun Hoe [Dept. Radiological Science, Cheongju University, Cheongju (Korea, Republic of)

    2016-11-15

    The purpose of this study was to assess clinical application of lower extremity CTA and lower extremity perfusion CT as a method of diagnostic for lower extremity atherosclerotic obliterans. From January to July 2016, 30 patients (mean age, 68) were studied with lower extremity CTA and lower extremity perfusion CT. 128 channel multi-detector row CT scans were acquired with a CT scanner (SOMATOM Definition Flash, Siemens medical solution, Germany) of lower extremity perfusion CT and lower extremity CTA. Acquired images were reconstructed with 3D workstation (Leonardo, Siemens, Germany). Site of lower extremity arterial occlusive and stenosis lesions were detected superficial femoral artery 36.6%, popliteal artery 23.4%, external iliac artery 16.7%, common femoral artery 13.3%, peroneal artery 10%. The mean total DLP comparison of lower extremity perfusion CT and lower extremity CTA, 650 mGy-cm and 675 mGy-cm, respectively. Lower extremity perfusion CT and lower extremity CTA were realized that were never be two examination that were exactly the same legions. Future through the development of lower extremity perfusion CT soft ware programs suggest possible clinical applications.

  9. Basic principles and applications of {sup 18}F-FDG-PET/CT in oral and maxillofacial imaging: A pictorial essay

    Energy Technology Data Exchange (ETDEWEB)

    Omami, Galal [Dept. of Oral Diagnosis and Polyclinics, Faculty of Dentistry, The Hong Kong University, Hong Kong (Hong Kong); Tamimi, Dania [BeamReaders Inc., Orlando (United States); Branstette, Barton F. [Dept. of Otolaryngology and Radiology, University of Pittsburgh School of Medicine, Pittsburgh (United States)

    2014-12-15

    A combination of positron emission tomography (PET) with 18F-labeled fluoro-2-deoxyglucose ({sup 18}F-FDG) and computed tomography ({sup 18}F-FDG-PET/CT) has increasingly become a widely used imaging modality for the diagnosis and management of head and neck cancer. On the basis of both recent literature and our professional experience, we present a set of principles with pictorial illustrations and clinical applications of FDG-PET/CT in the evaluation and management planning of squamous cell carcinoma of the oral cavity and oropharynx. We feel that this paper will be of interest and will aid the learning of oral and maxillofacial radiology trainees and practitioners.

  10. 双源CT临床应用新进展%Dual-source CT clinical application of new progress

    Institute of Scientific and Technical Information of China (English)

    黄远彬

    2014-01-01

    双源CT进行2种不同能量的X线同步扫描,可获得双能量图像,具有成像速度快,辐射剂量低,图像质量高的优点。双源CT进行冠状动脉成像,图像质量不再受患者心率过快、不规则以及屏气困难的影响,能获得可靠的冠状动脉图像,是目前无创性左室功能检查评价最具价值的检查方法之一。双源CT扫描时间缩短辐射剂量降低,有效克服部分患者移动伪影及呼吸伪影,适用于儿童患者及躁动患者的检查,为急性胸痛患者快速诊断提供安全有效手段。双源CT双能量虚拟平扫在头部、胸部、腹部疾病检查中已得到良好运用。双源CT在两种不同能量状态下的数据采集可对物质成分进行定性分析,拓宽了CT的应用范围,具有较好临床价值。%Dual source CT for 2 different energy X-ray scanning, can obtain the dual energy images, has fast imaging speed, low radiation dose, the advantages of high image quality. Dual source CT coronary artery imaging, image quality is not affected by the patient’s heart rate too fast, irregular and breath dififcult, can obtain the coronary artery image reliable;it is one of the current inspection method without evaluation and examination of the left ventricular function most value. Dual source CT scan can reduce the time of radiation dose, effectively overcome some patients moving artifact and respiratory artifacts, suitable for children patients and agitation of patients, to provide safe, effective method for the rapid diagnosis and emergency classiifcation of patients with acute chest pain. Dual energy CT virtual scan has been well used in the head, chest, abdominal disease examination. Dual source CT for qualitative analysis of components in two different energy state of the data acquisition, and widen the application range of CT, with good clinical application.

  11. Established, emerging and future applications of FDG-PET/CT in the uterine cancer

    Energy Technology Data Exchange (ETDEWEB)

    Kitajima, K., E-mail: kitajima@med.kobe-u.ac.j [PET Diagnosis, Institute of Biomedical Research and Innovation, Kobe (Japan); Murakami, K. [Division of Nuclear Medicine, Department of Diagnostic Radiology, Keio University School of Medicine, Tokyo (Japan); Kaji, Y. [Radiology, Dokkyo University School of Medicine, Mibu (Japan); Sakamoto, S. [PET center, Dokkyo Medical University Hospital, Mibu (Japan); Sugimura, K. [Department of Radiology, Kobe University Graduate School of Medicine, Kobe (Japan)

    2011-04-15

    Integrated positron emission tomography/computed tomography (PET/CT) with 2-[{sup 18}F]fluoro-2-deoxy-D-glucose (FDG) is a useful technique to acquire both glucose metabolic and anatomic imaging data using a single device in a single diagnostic session and has opened a new field in clinical oncologic imaging. FDG-PET/CT has been used successfully for the staging, optimization of treatment, re-staging, therapy monitoring, and prognostic prediction of uterine cervical cancer and endometrial cancer as well as various malignant tumours. The present review discusses the current role of FDG-PET/CT in the management of uterine cancer, discussing its usefulness and limitations in the imaging of these patients.

  12. Application of incremental algorithms to CT image reconstruction for sparse-view, noisy data

    DEFF Research Database (Denmark)

    Rose, Sean; Andersen, Martin Skovgaard; Sidky, Emil Y.;

    2014-01-01

    This conference contribution adapts an incremental framework for solving optimization problems of interest for sparse-view CT. From the incremental framework two algorithms are derived: one that combines a damped form of the algebraic reconstruction technique (ART) with a total-variation (TV) pro......) projection, and one that employs a modified damped ART, accounting for a weighted-quadratic data fidelity term, combined with TV projection. The algorithms are demonstrated on simulated, noisy, sparseview CT data.......This conference contribution adapts an incremental framework for solving optimization problems of interest for sparse-view CT. From the incremental framework two algorithms are derived: one that combines a damped form of the algebraic reconstruction technique (ART) with a total-variation (TV...

  13. Application of high resolution synchrotron micro-CT radiation in dental implant osseointegration

    DEFF Research Database (Denmark)

    Neldam, Camilla Albeck; Lauridsen, Torsten; Rack, Alexander

    2015-01-01

    The purpose of this study was to describe a refined method using high-resolution synchrotron radiation microtomography (SRmicro-CT) to evaluate osseointegration and peri-implant bone volume fraction after titanium dental implant insertion. SRmicro-CT is considered gold standard evaluating bone...... microarchitecture. Its high resolution, high contrast, and excellent high signal-to-noise-ratio all contribute to the highest spatial resolutions achievable today. Using SRmicro-CT at a voxel size of 5 μm in an experimental goat mandible model, the peri-implant bone volume fraction was found to quickly increase...... to 50% as the radial distance from the implant surface increased, and levelled out to approximately 80% at a distance of 400 μm. This method has been successful in depicting the bone and cavities in three dimensions thereby enabling us to give a more precise answer to the fraction of the bone-to-implant...

  14. Application of 18F-FDG PET/CT in Rare Metastatic Locations of Esophageal Carcinoma

    Directory of Open Access Journals (Sweden)

    Lan MA

    2015-06-01

    Full Text Available Background: Esophageal carcinoma is a kind of malignant tumor commonly seen in clinic. In recent years, positron emission tomography (PET/CT can accurately locate the general tumor nidi and PET/CT detection is recommended to determine the clinical stages of esophageal carcinoma. The common metastatic locations of esophageal carcinoma include lymph nodes (including cervical, supraclavicular and celiac lymph nodes, lung, liver and bone. This study aimed to summarize the distribution and incidence of rare metastatic locations and the characteristics of 18F-FDG PET/CT image in patients with esophageal carcinoma. Methods: A total of 185 patients with esophageal carcinoma undergoing 18F-FDG PET/CT detection in our hospital from August, 2009 to August, 2013 were collected to retrospectively analyze their clinical data. Metastatic nidi in rare locations were confirmed according to the results of clinical evaluation, imageological methods and follow-up. Results: A total of 19 patients with esophageal carcinoma suffered from metastases in rare locations according to the 18F-FDG PET/CT detection, with incidence of 10.27%. The rare locations included pleura (28.6%, peritoneum (23.8%, adrenal gland (1.6%, axillary lymph nodes (14.3%, nasal septum (4.8%, cerebellum (4.8% and napes (4.8%. Conclusion: 18F-FDG PET/CT detection can excellently detect the metastatic nidi in rare or uncommon locations and increase the accuracy of clinical staging and re-staging in patients with esophageal carcinoma, which has great guiding significance for clinical therapy.

  15. Application of18F-FDG PET/CT in Rare Metastatic Locations of Esophageal Carcinoma

    Institute of Scientific and Technical Information of China (English)

    MA Lan; GUAN Dan; DING Qi-yong; SHU Yong-qian; LIU Lian-ke

    2015-01-01

    Background: Esophageal carcinoma is a kind of malignant tumor commonly seen in clinic. In recent years, positron emission tomography (PET)/CT can accurately locate the general tumor nidi and PET/CT detection is recommended to determine the clinical stages of esophageal carcinoma. The common metastatic locations of esophageal carcinoma include lymph nodes (including cervical, supraclavicular and celiac lymph nodes), lung, liver and bone. This study aimed to summarize the distribution and incidence of rare metastatic locations and the characteristics of 18F-FDG PET/CT image in patients with esophageal carcinoma. Methods:A total of 185 patients with esophageal carcinoma undergoing18F-FDG PET/CT detection in our hospital from August, 2009 to August, 2013 were collected to retrospectively analyze their clinical data. Metastatic nidi in rare locations were conifrmed according to the results of clinical evaluation, imageological methods and follow-up. Results:A total of 19 patients with esophageal carcinoma suffered from metastases in rare locations according to the18F-FDG PET/CT detection, with incidence of 10.27%. The rare locations included pleura (28.6%), peritoneum (23.8%), adrenal gland (1.6%), axillary lymph nodes (14.3%), nasal septum (4.8%), cerebellum (4.8%) and napes (4.8%). Conclusion:18F-FDG PET/CT detection can excellently detect the metastatic nidi in rare or uncommon locations and increase the accuracy of clinical staging and re-staging in patients with esophageal carcinoma, which has great guiding signiifcance for clinical therapy.

  16. CT 灌注成像在胃癌诊断中的临床应用%Clinical application of CT perfusion imaging in gastric cancer diagnosis

    Institute of Scientific and Technical Information of China (English)

    朱艳琳; 黄陈恕; 孙宗琼

    2015-01-01

    目的:探讨胃癌CT灌注特点及具体灌注参数值和CT灌注成像在胃癌诊断中的临床应用价值。方法对经内镜病理确诊的50例胃癌和20例正常胃(对照组)行64层螺旋CT灌注成像检查,对所得容积数据采用CT灌注软件包的腹部肿瘤灌注协议(去卷积法)进行计算、制图和分析,分别测取血流量(BF)、血容量(BV)、平均通过时间(MTT)和毛细血管表面通透性(PS)四个参数值,然后应用SPSSl7.0软件进行统计分析。结果正常胃的BF、BV、MTT和PS平均值分别为75.0717.08ml/(min.100g)、7.951.81ml/100g、16.672.40s和7.981.30ml/(min.100g);胃癌的BF、BV、MTT和PS平均值分别为101.2848.01ml/(min.100g)、16.096.23ml/100g、9.574.99s和33.0023.27ml/(min.100g);两组比较,胃癌BF、BV、PS值升高,而MTT值下降,四个灌注参数值差异均具有非常显著的统计学意义(P<0.01)。结论胃CT灌注成像是一种功能成像,从血流动力学角度对胃癌的临床诊疗有一定价值。%Objective To explore the characteristics of gastric cancer's computed tomography (CT ) perfusion and specific values of perfusion parameter ,and to evaluate the potential of clinical application of CT perfusion imaging in diagnosis of gastric cancer .Methods Fifty patients with pathologically confirmed gastric cancer and 20 subjects without gastric disea‐ses (control group) were recruited and all the subjects received the examination of their stomachs by using 64‐slice spiral CT perfusion imaging . The obtained volume data were used for calculation ,mapping and analysis by using abdominal tumor perfusion protocol (deconvolution method) of CT perfusion software package ,so as to measure four parameter val‐ues ,i .e .,blood flow (BF) ,blood volume (BV) ,mean transit time (M TT ) and permeability surface (PS) ,respectively . Results The mean perfusion

  17. Development of a Carbon Nanotube-Based Micro-CT and its Applications in Preclinical Research

    Science.gov (United States)

    Burk, Laurel May

    Due to the dependence of researchers on mouse models for the study of human disease, diagnostic tools available in the clinic must be modified for use on these much smaller subjects. In addition to high spatial resolution, cardiac and lung imaging of mice presents extreme temporal challenges, and physiological gating methods must be developed in order to image these organs without motion blur. Commercially available micro-CT imaging devices are equipped with conventional thermionic x-ray sources and have a limited temporal response and are not ideal for in vivo small animal studies. Recent development of a field-emission x-ray source with carbon nanotube (CNT) cathode in our lab presented the opportunity to create a micro-CT device well-suited for in vivo lung and cardiac imaging of murine models for human disease. The goal of this thesis work was to present such a device, to develop and refine protocols which allow high resolution in vivo imaging of free-breathing mice, and to demonstrate the use of this new imaging tool for the study many different disease models. In Chapter 1, I provide background information about x-rays, CT imaging, and small animal micro-CT. In Chapter 2, CNT-based x-ray sources are explained, and details of a micro-focus x-ray tube specialized for micro-CT imaging are presented. In Chapter 3, the first and second generation CNT micro-CT devices are characterized, and successful respiratory- and cardiac-gated live animal imaging on normal, wild-type mice is achieved. In Chapter 4, respiratory-gated imaging of mouse disease models is demonstrated, limitations to the method are discussed, and a new contactless respiration sensor is presented which addresses many of these limitations. In Chapter 5, cardiac-gated imaging of disease models is demonstrated, including studies of aortic calcification, left ventricular hypertrophy, and myocardial infarction. In Chapter 6, several methods for image and system improvement are explored, and radiation

  18. Clinical application, research progress of CT spectral imaging%CT 光谱成像技术的临床应用与研究进展

    Institute of Scientific and Technical Information of China (English)

    李彬; 汤素琼; 杨建林; 黄华明; 张景宇; 徐玉栋

    2015-01-01

    CT光谱成像功能作为CT的一项新技术,可同时、同相位获得两个不同能量水平的影像,从而瞬间重建出40千伏值至140千伏值的高清单能图像,为疾病的早期定性、定量诊断提供了可靠数据、信息,在临床及科研应用中具有巨大的潜力,为科学研究和临床应用提供了更宽广的发展空间。%As a new technique ,CT spectral imaging can obtain two images of different energy level at same phase simultaneously ,then immediately rebuild high definition monoenergetic images ranging from 40 kV to 140 kV .It provides reliable data and information for early qualitative and quantitative diagnosis of diseases ,which possess huge potential in clinical and science research ;and more extensive developing space for developing of scientific research and clinical application .

  19. Current State and Progress of Coronary Angiography in Multi-slice Spiral Computed Tomography Imaging Techniques%多排螺旋CT在冠状动脉成像技术中的现状与进展

    Institute of Scientific and Technical Information of China (English)

    胡斌; 徐文坚; 陈海松

    2012-01-01

    多层螺旋CT( mulil slice spiral CT,MSCT)技术的进步为无创性冠状动脉造影提供了广阔的前景,临床应用备受关注.特别是64层CT的出现,空间分辨率、时间分辨率大大提高,心电门控技术及三维后处理技术拓宽了CT在冠状动脉成像中的应用范围.本文阐述了CT在冠状动脉成像技术及影响因素,并对其现状及进展情况作综述.%Multi-detector row CT imaging techniques has great potential for development of noninvasive imaging of the coronary arteries. Coronary CT angiography in clinical utility field was paid highly attention to. Especially current computed tomography (64 slice CT) techniques combine high speed and spatial resolution with electrocardiography synchronization and three-dimensional post processing technology, the scope of coronary CT angiography was widen. This review article will describe the coronary angiography technology of multi-detector row CT and the factors as they relate to the current and future role of coronary CT angiography.

  20. Thoracic CT

    Science.gov (United States)

    ... lungs; CT scan - chest Images CT scan Thyroid cancer - CT scan Pulmonary nodule, solitary - CT scan Lung mass, right upper ... Chest Injuries and Disorders CT Scans Emphysema Lung Cancer Lung Diseases Pleural Disorders Pneumonia Pulmonary Embolism Tuberculosis Browse the Encyclopedia A.D.A. ...

  1. Region-Based 4D Tomographic Image Reconstruction: Application to Cardiac X-ray CT

    NARCIS (Netherlands)

    Eyndhoven, G. Van; Batenburg, K.J.; Sijbers, J.

    2015-01-01

    X-ray computed tomography (CT) is a powerful tool for noninvasive cardiac imaging. However, radiation dose is a major issue. In this paper, we propose an iterative reconstruction method that reduces the radiation dose without compromising image quality. This is achieved by exploiting prior knowledge

  2. Anatomical and CT approach of the adipose tissue: application in morbid obesity.

    Science.gov (United States)

    Renard, Yohann; Diaz Cives, Anna; Veyrie, Nicolas; Bouillot, Jean Luc; Bertin, Eric; Labrousse, Marc; Kianmanesh, Reza; Avisse, Claude

    2015-11-01

    The importance and proportion of visceral adipose tissue (VAT) represent the best criterion to define obesity. Because VAT value is difficult to obtain in clinical practice, the indication for bariatric surgery is still based at present on Body Mass index (BMI), even though BMI is a poor predictor of obesity-related morbid complications. This correlation study aimed at determining a simple and accurate computed tomography (CT) anatomic marker, which can be easily used clinically, well correlated with the volume of VAT and consequently with morbid complications. We studied 108 CT scans of patients presenting with morbid obesity. Several simplified measures (external and internal abdominal diameters and circumferences) were conducted on CT scan view, going through the fourth lumbar vertebra (L4), in addition to various vertebral measurements (area of the vertebra, sagittal and transversal diameters), VAT and subcutaneous adipose tissue (SAT). Then, we reported the simplified measures values on the vertebral areas, and we calculated the Bertin index. Finally, we conducted a correlation study between all variables to obtain accurate VAT measurements. The internal abdominal circumference and the Bertin index showed the best correlations with VAT in morbidly obese patients (r = 0.84 and 0.85, respectively). BMI and anthropometric measures were not correlated with VAT. CT scan study allows to simply approximate VAT value in morbidly obese patients. An abdominal CT scan could be part of the tests used in the evaluation of obese patients to base therapeutic strategies on VAT values and not on BMI as it is the case today.

  3. 64层螺旋CT在急性肺挫伤诊断中的应用价值%The Value of Applying 64 Multi-slice CT(MSCT) to the Diagnosis of Acute Pulmonary Contusion

    Institute of Scientific and Technical Information of China (English)

    殷国生; 张树桐

    2012-01-01

    目的:探讨64层螺旋CT在急性肺挫伤诊断中的应用价值。方法:收集临床怀疑肺挫伤患者461例,所有患者于入院后1 h内行64层螺旋CT胸部平扫,判断有无肺挫伤。结果:诊断肺挫伤113例,双肺广泛性挫伤12例,右肺挫伤61例,左肺挫伤40例;肺不张22例;合并气胸33例,其中血气胸10例;肋骨骨折38例,锁骨骨折4例,肩胛骨骨折2例,胸椎骨折2例,胸骨骨折1例;皮下气肿87例,纵膈积气11例,纵膈血肿3例。结论:64层螺旋CT能有效诊断肺挫伤,尤其对影像学征象较隐蔽的病变更具优势。%Objective: To explore the clinical application of 64-MS CT to acute pulmonary contusion.Methods: A retrospective study was undertaken in 461 cases who were doubted acute pulmonary clinically.They were received CT scan within one hour.Results: 113 cases were diagnosed acute pulmonay contusion including 12 cases with wide-bound pulmonary contusion in pulmones,61 cases with right lung,40 cases with left lung,22 cases with pulmonary atelectasis,33 cases with aeropleura,10 cases with hemopneumothorax,38 cases with fracture of rib,4 cases with fracture of clavicle,2 cases with fracture of shoulder blade,2 cases with thoracic vertebral fracture,1 case with fracture of sternum,87 cases with pneumoderma,11 cases with mediastinal emphesema and 3 cases with mediastinal hematoma.Conclusion: 64-MSCT can effectively diagnose acute pulmonary contusion,especially in diagnosing the larvaceous imaging signs.

  4. Automated quantitation of cold-inducible human brown adipose tissue with FDG PET/CT with application to fibromyalgia

    Science.gov (United States)

    Pardo, José V; Lee, Joel T; Larson, Robert C; Thuras, Paul; Larson, Alice A

    2017-01-01

    Increasing recognition of the importance of brown adipose tissue (BAT) motivates the development of reproducible and quantitative methods for measuring it. Positron emission tomography (PET)/computerized tomography (CT) with 18F-fluorodeoxyglucose (FDG) has become the principal method to non-invasively detect brown adipose tissue (BAT) in humans. Improvements in quantitation and standardization will drive further clinical application. One disorder hypothesized to involve dysregulation in thermoregulation and the processing of pain involving BAT is fibromyalgia syndrome (FMS). This report describes an approach with additional technical standardization to measure cold-inducible, BAT activity (ci-BAT) semi-quantitatively and reliably with minimal operator intervention with the FDG PET/CT technique. Ci-BAT was measured to test whether FMS patients have decreased BAT activation compared to normal controls. Threshold parameters to optimally separate ci-BAT from non-ci-BAT were developed based on the distribution of the pixel-wise parametric data from each merged PET/CT scan for each study session occurring on different days. BAT activity was the same under warm conditions in both control and FMS subjects attesting to reproducibility and reliability. However, considerable variability arose between groups at cool temperatures consistent with other literature. Increases in ci-BAT activity were significantly less in FMS patients than in controls, as hypothesized. Ci-BAT recruitment can be quantified non-invasively using FDG PET/CT using semi-automated techniques in human subjects across different diagnostic groups or within groups undergoing manipulations of interest. PMID:28123865

  5. MSCTV直接静脉造影诊断静脉受阻性病变的价值%Value of direct multi-slice computed tomography venography in diagnosing venous obstructive disease

    Institute of Scientific and Technical Information of China (English)

    赖伟; 刘建新; 林晓平

    2015-01-01

    目的:探讨多层螺旋CT直接静脉造影(MSCTV)诊断静脉受阻性病变的临床价值。方法收集35例应用直接MSCTV诊断并经临床证实的静脉受阻性病变患者的临床及影像学资料,研究MSCTV成像方法,分析静脉受阻性病变的影像学表现特征。结果本组共35例患者,其中下肢深静脉血栓19例,上肢深静脉血栓2例,深静脉瘤栓3例,单纯性下肢静脉曲张11例。MSCTV深静脉血栓表现为静脉腔内的充盈缺损,管腔中断,侧支循环形成。深静脉瘤栓表现为静脉腔内和/或腔外软组织肿块影,管腔不规则狭窄并充盈缺损。单纯性下肢静脉曲张表现为静脉血管增多、增粗、纡曲。结论静脉受阻性病变具有一定的MSCT征象,MSCTV对诊断静脉受阻性病变具有较大的临床价值。%Objective To explore the clinical value of direct multi-slice computed tomography venography (MSCTV) in diagnosing venous obstructive disease. Methods The clinical and imaging data of 35 cases of venous obstructive disease diagnosed by MSCTV and confirmed in clinic were reviewed. The imaging features of venous ob-structive disease were analyzed. Results There were a total of 35 cases, with 19 cases located in deep venous throm-bosis of lower extremity, 2 cases located in deep venous thrombosis of upper extremity, 3 cases located in deep venous tumor thrombus, and 11 cases located in simple vein varicosis of lower extremity. MSCTV manifestations of deep ve-nous thrombosis included filling defect in vein intraluminal, luminal interrupt, and formation of collateral circulation. MSCTV manifestations of deep venous tumor thrombus showed soft tissue mass in the vein cavity and/or extralumi-nal, irregular filling defect and stenosis in lumen. Simple varicose veins of lower extremity showed increased number of veins, as well as thickening and tortuosity. Conclusion MSCTV manifestations of venous obstructive disease have some specific features

  6. Spontaneous isolated dissection of the superior mesenteric artery:multi-slice computed tomographic angiography findings in seven cases%MSCT血管成像对孤立性肠系膜上动脉夹层的诊断价值

    Institute of Scientific and Technical Information of China (English)

    陈则君; 谢旭纲; 孟宪平; 朱建新; 王伯元

    2011-01-01

    目的:探讨MSCT血管成像诊断孤立性肠系膜上动脉夹层(SISAMD)的临床应用价值.方法:对7例急性肠缺血患者行MSCT血管成像,采用容积再现(VR)、多平面重组(MPR)、曲面重组(CPR)及最大密度投影(MIP)重组图像,由两位经验丰富的心血管影像医师评估夹层的部位和范围.结果:SISAMD与主动脉夹层CT血管成像(CTA)表现相同,CTA清晰显示撕裂内膜5例,破裂口均位于肠系膜上动脉(SMA)近心端.根据Yun分型:Ⅰ型1例,Ⅱa型3例,Ⅱb型2例,Ⅲ型1例.SMA直径增粗2例,SMA周围脂肪间隙模糊2例,局部回肠壁增厚、水肿2例,升结肠扩张、积液1例,腹腔及盆腔内少量积液2例.结论:MSCTA能清晰显示病变特征和累及范围,是孤立性肠系膜上动脉夹层首选的检查方法.%Objective : To asscss the value of multi-slice computed tomographic angiography (MSCTA) in the diagno sis of spontancous isolated dissection of superior mesenteric artery (SMA). Methods:7 patients with clinically suspected a cute mesenteric ischemia underwent MSCTA. Multiplanar and three-dimensional images were obtained by imaging postpro cessing techniques including volume rendering technique (VRT) , multiplanar reconstruction (MPR) , curved planar reforma tion (CPR) and maximum intensity projection (MIP) on a workstation. Image reading was performed in consensus by two experienced cardiovascular radiologists. Results: According to Yun's classification,there were one case of type Ⅰ , three type Ⅱ a,two type Ⅱ b and one type Ⅲ . Spontaneous isolated dissection of SMA displays the same MSCTA features as aortic dis section. Intimal flaps were seen in five patients,with intimal tears at the proximal SMA. Other MSCTA findings associated with spontaneous isolated dissection of SMA were enlarged diameter of the SMA (n=2) ,increased attenuation of the fat a round the SMA (n=2) ,local ileum wall thickening due to edema (n=2) , dilated ascending colon (n=1) and hemorrhagic

  7. Measuring temporal resolution of cardiac CT reconstructions

    Science.gov (United States)

    Matthews, David; Heuscher, Dominic

    2005-04-01

    Multi-slice CT today is capable of imaging the heart with excellent temporal resolution. Algorithms have been developed to perform reconstructions combining data from multiple cardiac cycles. This paper presents a simulation phantom that enables a direct measurement of the actual temporal resolution achieved by these algorithms. This is not only useful for assessing the temporal resolution but also for validating the algorithms themselves. A simulation phantom was developed that consists of a 20 cm. diameter water phantom containing an array of cylinders whose intensities are pulsed for various durations ranging from 10 msec. to 250 msec. The intensity varied between the background value of water (0 HU) and 800 HU. By measuring the nominal attenuation value at the center of each cylinder, a curve can be derived representing the response over the given temporal range. A temporal resolution representing the FWHM value is determined based on the half-max value of this curve. Reconstructions were performed using a multi-cycle cardiac algorithm described previously in the literature. The measured FWHM values agree quite well to the temporal resolution predicted by the cardiac algorithm itself. Even the variation along the longitudinal axis can be accounted for by the predicted values. A simulated phantom can be used to accurately assess the temporal resolution of cardiac reconstruction algorithms. Excellent agreement was achieved between the predicted and measured temporal resolution values for the multi-cycle algorithm used in this study.

  8. New approach to diagnosis of pulmonary embolism using multislice CT

    Science.gov (United States)

    Niethammer, Matthias U.; Schoepf, Uwe J.; Wildberger, Hoachim E.; Klotz, Ernst; Fichte, Heinz; Schaller, Stefan

    2001-05-01

    Suspected pulmonary embolism (PE) is a common indication for CT scanning of the thorax. Usually, intravenous contrast agent is administered utilizing a power-injector and the vascular structures are examined for the presence of pulmonary emboli. Current Multi-Slice CT-technology allows extending this morphological analysis by adding a more functional visualization of the actual parenchymal perfusion disturbance. We have developed a new image processing technique which allows selective color encoded display of parenchymal enhancement of the lung, which will be reduced in the presence of PE. Based on thin slice reconstructions an automatic 3D segmentation of the lung is performed followed by threshold based extraction of the major airways and vascular structures. This allows applying an adaptive 3D low-pass filter to the parenchymal volume only. The filtered volume data are then color encoded and overlaid onto the original CT-images. This combination of low-resolution perfusion-weighted color maps and high-resolution gray scale structural data from the same data set greatly enhances visualization of spatial relationships. The resulting images can be displayed in axial, sagittal and coronal orientation. Initial experience indicates that this new technique provides relevant additional information for the clinical management of patients with proven PE. A larger controlled patient study is under way.

  9. Performance and applications of GaAs:Cr-based Medipix detector in X-ray CT

    Science.gov (United States)

    Kozhevnikov, D.; Chelkov, G.; Demichev, M.; Gridin, A.; Smolyanskiy, P.; Zhemchugov, A.

    2017-01-01

    In the recent years, the method of single photon counting X-ray μ-CT is being actively developed and applied in various fields. Results of our studies carried out using the MARS μ-CT scanner equipped with GaAs Medipix-based camera are presented. The procedure of mechanical alignment of the scanner is described, including direct and indirect measurements of the spatial resolution. The software chain for data processing and reconstruction has been developed and reported. We demonstrate the possibility to apply the scanner for research in geology and medicine and provide demo images of geological samples (chrome spinellids, titanium magnetite ore) and medical samples (atherosclerotic plaque, abdominal aortic aneurysm). The first results of multi-energy scans using GaAs:Cr-based camera are shown.

  10. Applications of PET/CT in Pediatric Patients with Fever of Unknown Origin.

    Science.gov (United States)

    Houseni, Mohamed; Chamroonrat, Wichana; Servaes, Sabah; Alavi, Abass; Zhuang, Hongming

    2008-10-01

    Fever of unknown origin (FUO) is a challenging problem. In children, FUO is critical, as it may hide a life threatening disease. One of the main difficulties in managing patients with FUO is the absence of a universal diagnostic approach. There are many impending causes for FUO. Most cases are attributable to atypical presentations of common diseases. The key to establishing the diagnosis is through comprehensive clinical data and targeted investigations. Despite all efforts, the underlying cause remains undiagnosed in many cases. PET/CT is a powerful modality that has been proven to be useful in many common causes that could emerge as FUO. This article reviews the utility of PET/CT imaging in children with FUO. Copyright © 2009 Elsevier Inc. All rights reserved.

  11. Spatially varying Riemannian elasticity regularization: Application to thoracic CT registration in image-guided radiotherapy

    DEFF Research Database (Denmark)

    Bjerre, Troels; Hansen, Mads Fogtmann; Aznar, M.;

    2012-01-01

    For deformable registration of computed tomography (CT) scans in image guided radiation therapy (IGRT) we apply Riemannian elasticity regularization. We explore the use of spatially varying elasticity parameters to encourage bone rigidity and local tissue volume change only in the gross tumor......-model we achieved a total mean target registration error (TRE) of 0.92 ± 0.49 mm. Using spatially varying regularization for the HL case, deformation was limited to the GTV and lungs....

  12. Application of incremental algorithms to CT image reconstruction for sparse-view, noisy data

    OpenAIRE

    Rose, Sean; Andersen, Martin Skovgaard; Sidky, Emil Y.; Pan, Xiaochuan

    2014-01-01

    This conference contribution adapts an incremental framework for solving optimization problems of interest for sparse-view CT. From the incremental framework two algorithms are derived: one that combines a damped form of the algebraic reconstruction technique (ART) with a total-variation (TV) projection, and one that employs a modified damped ART, accounting for a weighted-quadratic data fidelity term, combined with TV projection. The algorithms are demonstrated on simulated, noisy, sparsevie...

  13. Application of region selective embedded zerotree wavelet coder in CT image compression.

    Science.gov (United States)

    Li, Guoli; Zhang, Jian; Wang, Qunjing; Hu, Cungang; Deng, Na; Li, Jianping

    2005-01-01

    Compression is necessary in medical image preservation because of the huge data quantity. Medical images are different from the common images because of their own characteristics, for example, part of information in CT image is useless, and it's a kind of resource waste to save this part information. The region selective EZW coder was proposed with which only useful part of image was selected and compressed, and the test image provides good result.

  14. Application of Preoperative CT/MRI Image Fusion in Target Positioning for Deep Brain Stimulation

    Institute of Scientific and Technical Information of China (English)

    Yu Wang; Zi-yuan Liu; Wan-chen Dou; Wen-bin Ma; Ren-zhi Wang; Yi Guo

    2016-01-01

    Objective To explore the efficacy of target positioning by preoperative CT/MRI image fusion technique in deep brain stimulation. Methods We retrospectively analyzed the clinical data and images of 79 cases (68 with Parkinson’s disease, 11 with dystonia) who received preoperative CT/MRI image fusion in target positioning of subthalamic nucleus in deep brain stimulation. Deviation of implanted electrodes from the target nucleus of each patient were measured. Neurological evaluations of each patient before and after the treatment were performed and compared. Complications of the positioning and treatment were recorded. Results The mean deviations of the electrodes implanted on X, Y, and Z axis were 0.5 mm, 0.6 mm, and 0.6 mm, respectively. Postoperative neurologic evaluations scores of unified Parkinson’s disease rating scale (UPDRS) for Parkinson’s disease and Burke-Fahn-Marsden Dystonia Rating Scale (BFMDRS) for dystonia patients improved significantly compared to the preoperative scores (P<0.001); Complications occurred in 10.1% (8/79) patients, and main side effects were dysarthria and diplopia. Conclusion Target positioning by preoperative CT/MRI image fusion technique in deep brain stimulation has high accuracy and good clinical outcomes.

  15. A multicenter, randomized controlled trial of immediate total-body CT scanning in trauma patients (REACT-2

    Directory of Open Access Journals (Sweden)

    Sierink Joanne C

    2012-03-01

    Full Text Available Abstract Background Computed tomography (CT scanning has become essential in the early diagnostic phase of trauma care because of its high diagnostic accuracy. The introduction of multi-slice CT scanners and infrastructural improvements made total-body CT scanning technically feasible and its usage is currently becoming common practice in several trauma centers. However, literature provides limited evidence whether immediate total-body CT leads to better clinical outcome then conventional radiographic imaging supplemented with selective CT scanning in trauma patients. The aim of the REACT-2 trial is to determine the value of immediate total-body CT scanning in trauma patients. Methods/design The REACT-2 trial is an international, multicenter randomized clinical trial. All participating trauma centers have a multi-slice CT scanner located in the trauma room or at the Emergency Department (ED. All adult, non-pregnant, severely injured trauma patients according to predefined criteria will be included. Patients in whom direct scanning will hamper necessary cardiopulmonary resuscitation or who require an immediate operation because of imminent death (both as judged by the trauma team leader are excluded. Randomization will be computer assisted. The intervention group will receive a contrast-enhanced total-body CT scan (head to pelvis during the primary survey. The control group will be evaluated according to local conventional trauma imaging protocols (based on ATLS guidelines supplemented with selective CT scanning. Primary outcome will be in-hospital mortality. Secondary outcomes are differences in mortality and morbidity during the first year post trauma, several trauma work-up time intervals, radiation exposure, general health and quality of life at 6 and 12 months post trauma and cost-effectiveness. Discussion The REACT-2 trial is a multicenter randomized clinical trial that will provide evidence on the value of immediate total-body CT scanning

  16. HDRMC, an accelerated Monte Carlo dose calculator for high dose rate brachytherapy with CT-compatible applicators

    Energy Technology Data Exchange (ETDEWEB)

    Chibani, Omar, E-mail: omar.chibani@fccc.edu; C-M Ma, Charlie [Fox Chase Cancer Center, Philadelphia, Pennsylvania 19111 (United States)

    2014-05-15

    Purpose: To present a new accelerated Monte Carlo code for CT-based dose calculations in high dose rate (HDR) brachytherapy. The new code (HDRMC) accounts for both tissue and nontissue heterogeneities (applicator and contrast medium). Methods: HDRMC uses a fast ray-tracing technique and detailed physics algorithms to transport photons through a 3D mesh of voxels representing the patient anatomy with applicator and contrast medium included. A precalculated phase space file for the{sup 192}Ir source is used as source term. HDRM is calibrated to calculated absolute dose for real plans. A postprocessing technique is used to include the exact density and composition of nontissue heterogeneities in the 3D phantom. Dwell positions and angular orientations of the source are reconstructed using data from the treatment planning system (TPS). Structure contours are also imported from the TPS to recalculate dose-volume histograms. Results: HDRMC was first benchmarked against the MCNP5 code for a single source in homogenous water and for a loaded gynecologic applicator in water. The accuracy of the voxel-based applicator model used in HDRMC was also verified by comparing 3D dose distributions and dose-volume parameters obtained using 1-mm{sup 3} versus 2-mm{sup 3} phantom resolutions. HDRMC can calculate the 3D dose distribution for a typical HDR cervix case with 2-mm resolution in 5 min on a single CPU. Examples of heterogeneity effects for two clinical cases (cervix and esophagus) were demonstrated using HDRMC. The neglect of tissue heterogeneity for the esophageal case leads to the overestimate of CTV D90, CTV D100, and spinal cord maximum dose by 3.2%, 3.9%, and 3.6%, respectively. Conclusions: A fast Monte Carlo code for CT-based dose calculations which does not require a prebuilt applicator model is developed for those HDR brachytherapy treatments that use CT-compatible applicators. Tissue and nontissue heterogeneities should be taken into account in modern HDR

  17. Comparison between traditional laboratory tests, permeability measurements and CT-based fluid flow modelling for cultural heritage applications

    Energy Technology Data Exchange (ETDEWEB)

    De Boever, Wesley, E-mail: Wesley.deboever@ugent.be [UGCT/PProGRess, Dept. of Geology, Ghent University, Krijgslaan 281, 9000 Ghent (Belgium); Bultreys, Tom; Derluyn, Hannelore [UGCT/PProGRess, Dept. of Geology, Ghent University, Krijgslaan 281, 9000 Ghent (Belgium); Van Hoorebeke, Luc [UGCT/Radiation Physics, Dept. of Physics & Astronomy, Ghent University, Proeftuinstraat 86, 9000 Ghent (Belgium); Cnudde, Veerle [UGCT/PProGRess, Dept. of Geology, Ghent University, Krijgslaan 281, 9000 Ghent (Belgium)

    2016-06-01

    In this paper, we examine the possibility to use on-site permeability measurements for cultural heritage applications as an alternative for traditional laboratory tests such as determination of the capillary absorption coefficient. These on-site measurements, performed with a portable air permeameter, were correlated with the pore network properties of eight sandstones and one granular limestone that are discussed in this paper. The network properties of the 9 materials tested in this study were obtained from micro-computed tomography (μCT) and compared to measurements and calculations of permeability and the capillary absorption rate of the stones under investigation, in order to find the correlation between pore network characteristics and fluid management characteristics of these sandstones. Results show a good correlation between capillary absorption, permeability and network properties, opening the possibility of using on-site permeability measurements as a standard method in cultural heritage applications. - Highlights: • Measurements of capillary absorption are compared to in-situ permeability. • We obtain pore size distribution and connectivity by using micro-CT. • These properties explain correlation between permeability and capillarity. • Correlation between both methods is good to excellent. • Permeability measurements could be a good alternative to capillarity measurement.

  18. Comparison between traditional laboratory tests, permeability measurements and CT-based fluid flow modelling for cultural heritage applications.

    Science.gov (United States)

    De Boever, Wesley; Bultreys, Tom; Derluyn, Hannelore; Van Hoorebeke, Luc; Cnudde, Veerle

    2016-06-01

    In this paper, we examine the possibility to use on-site permeability measurements for cultural heritage applications as an alternative for traditional laboratory tests such as determination of the capillary absorption coefficient. These on-site measurements, performed with a portable air permeameter, were correlated with the pore network properties of eight sandstones and one granular limestone that are discussed in this paper. The network properties of the 9 materials tested in this study were obtained from micro-computed tomography (μCT) and compared to measurements and calculations of permeability and the capillary absorption rate of the stones under investigation, in order to find the correlation between pore network characteristics and fluid management characteristics of these sandstones. Results show a good correlation between capillary absorption, permeability and network properties, opening the possibility of using on-site permeability measurements as a standard method in cultural heritage applications.

  19. Applications of the Medipix3-CT in combination with iterative reconstruction techniques

    Science.gov (United States)

    Fischer, F.; Procz, S.; Fauler, A.; Fiederle, M.

    2016-02-01

    The pixelated semiconductor detectors of the Medipix family with their photon-counting abilities offer the possibility of high quality X-ray radiography as well as computed tomography. The generated signal from each photon is amplified and shaped before it is compared to an energy threshold. For a photon with an energy above the threshold the counter is incremented by one count. Photons below the operator-defined threshold do not increment the counter and therefore do not participate in the image formation. Furthermore, compared to other detectors like scintillators, an additional conversion step is dispensed due to the direct converting nature of photon-counting detectors, leading to a higher signal-to-noise-ratio. Additionally, the photon processing capabilities of photon-counting detectors allow photons to be weighted equally and not proportional to their energy as it is the case for charge integrating devices, where high energy photons are weighted stronger than low energy photons. Compared to integrating devices, this leads to an increase in contrast for images of both high and low contrast objects, hence improve object information. The use of photon-counting detectors in combination with iterative reconstruction techniques based on OSEM (ordered subset expectation maximization) algorithms is the basis of our computed tomography scans for material analysis. Due to its ability to operate with highly undersampled data sets, iterative reconstruction offers the possibility to decrease dose in CT scans. In order to identify the limits of the data set reduction, a first series of scans was performed to test, under real conditions, the CT-image quality when a strongly reduced amount of projections is used for reconstruction. In addition, the effect of a total variation minimization tool on these undersampled data sets was evaluated. Furthermore, this paper includes a number of recent CT-results with scans performed at two different setups within our facility.

  20. On two-parameter models of photon cross sections: application to dual-energy CT imaging.

    Science.gov (United States)

    Williamson, Jeffrey F; Li, Sicong; Devic, Slobodan; Whiting, Bruce R; Lerma, Fritz A

    2006-11-01

    The goal of this study is to evaluate the theoretically achievable accuracy in estimating photon cross sections at low energies (20-1000 keV) from idealized dual-energy x-ray computed tomography (CT) images. Cross-section estimation from dual-energy measurements requires a model that can accurately represent photon cross sections of any biological material as a function of energy by specifying only two characteristic parameters of the underlying material, e.g., effective atomic number and density. This paper evaluates the accuracy of two commonly used two-parameter cross-section models for postprocessing idealized measurements derived from dual-energy CT images. The parametric fit model (PFM) accounts for electron-binding effects and photoelectric absorption by power functions in atomic number and energy and scattering by the Klein-Nishina cross section. The basis-vector model (BVM) assumes that attenuation coefficients of any biological substance can be approximated by a linear combination of mass attenuation coefficients of two dissimilar basis substances. Both PFM and BVM were fit to a modern cross-section library for a range of elements and mixtures representative of naturally occurring biological materials (Z = 2-20). The PFM model, in conjunction with the effective atomic number approximation, yields estimated the total linear cross-section estimates with mean absolute and maximum error ranges of 0.6%-2.2% and 1%-6%, respectively. The corresponding error ranges for BVM estimates were 0.02%-0.15% and 0.1%-0.5%. However, for photoelectric absorption frequency, the PFM absolute mean and maximum errors were 10.8%-22.4% and 29%-50%, compared with corresponding BVM errors of 0.4%-11.3% and 0.5%-17.0%, respectively. Both models were found to exhibit similar sensitivities to image-intensity measurement uncertainties. Of the two models, BVM is the most promising approach for realizing dual-energy CT cross-section measurement.

  1. Hyperparathyroidism: CT and MR findings; Hyperparathyroidie: applications du scanner et de l'IRM

    Energy Technology Data Exchange (ETDEWEB)

    Ernst, O. [Hopital Huriez, CHRU de Lille, Service de Radiologie, 59 - Lille (France)

    2009-03-15

    3-Phase contrast material enhanced CT provides great sensitivity for accurate localization of hyper-functioning parathyroid glands. Density measurements can assist in differentiating adenomas from lymph nodes and normal thyroid tissue. The spontaneous attenuation of parathyroid adenomas is lower than 80 HU, whereas the density of normal thyroid tissue is above 80 HU. Forty five seconds after contrast injection, adenomas have a density > 130 HU, whereas lymph nodes have a density < 130 HU. Furthermore, between 45 and 70 seconds after injection, the attenuation of parathyroid adenomas decreases (>20 UH ) whereas the attenuation of lymph nodes increases. (author)

  2. High throughput static and dynamic small animal imaging using clinical PET/CT: potential preclinical applications

    Energy Technology Data Exchange (ETDEWEB)

    Aide, Nicolas [Francois Baclesse Cancer Centre and Caen University, Bioticla Team, EA1792, IFR 146 ICORE, GRECAN, Caen (France); Caen University Hospital and Francois Baclesse Cancer Centre, PET Unit, Caen (France); Peter MacCallum Cancer Centre, Centre for Molecular Imaging, East Melbourne (Australia); Centre Francois Baclesse, Nuclear Medicine Department, Caen cedex 5 (France); Desmonts, Cedric; Agostini, Denis; Bardet, Stephane; Bouvard, Gerard [Caen University Hospital and Francois Baclesse Cancer Centre, PET Unit, Caen (France); Beauregard, Jean-Mathieu; Roselt, Peter; Neels, Oliver [Peter MacCallum Cancer Centre, Centre for Molecular Imaging, East Melbourne (Australia); Beyer, Thomas [cmi-experts GmbH, Zurich (Switzerland); University Hospital Essen, Department of Nuclear Medicine, Essen (Germany); University Hospital Bern, Institute of Nuclear Medicine, Bern (Switzerland); Kinross, Kathryn [Peter MacCallum Cancer Centre, Centre for Molecular Imaging, East Melbourne (Australia); Peter MacCallum Cancer Centre, Sir Donald and Lady Trescowthick Laboratories, East Melbourne (Australia); Hicks, Rodney J. [Peter MacCallum Cancer Centre, Centre for Molecular Imaging, East Melbourne (Australia); University of Melbourne, The Department of Medicine, Parkville (Australia)

    2010-05-15

    The objective of the study was to evaluate state-of-the-art clinical PET/CT technology in performing static and dynamic imaging of several mice simultaneously. A mouse-sized phantom was imaged mimicking simultaneous imaging of three mice with computation of recovery coefficients (RCs) and spillover ratios (SORs). Fifteen mice harbouring abdominal or subcutaneous tumours were imaged on clinical PET/CT with point spread function (PSF) reconstruction after injection of [18F]fluorodeoxyglucose or [18F]fluorothymidine. Three of these mice were imaged alone and simultaneously at radial positions -5, 0 and 5 cm. The remaining 12 tumour-bearing mice were imaged in groups of 3 to establish the quantitative accuracy of PET data using ex vivo gamma counting as the reference. Finally, a dynamic scan was performed in three mice simultaneously after the injection of {sup 68}Ga-ethylenediaminetetraacetic acid (EDTA). For typical lesion sizes of 7-8 mm phantom experiments indicated RCs of 0.42 and 0.76 for ordered subsets expectation maximization (OSEM) and PSF reconstruction, respectively. For PSF reconstruction, SOR{sub air} and SOR{sub water} were 5.3 and 7.5%, respectively. A strong correlation (r {sup 2} = 0.97, p < 0.0001) between quantitative data obtained in mice imaged alone and simultaneously in a group of three was found following PSF reconstruction. The correlation between ex vivo counting and PET/CT data was better with PSF reconstruction (r {sup 2} = 0.98; slope = 0.89, p < 0.0001) than without (r {sup 2} = 0.96; slope = 0.62, p < 0.001). Valid time-activity curves of the blood pool, kidneys and bladder could be derived from {sup 68}Ga-EDTA dynamic acquisition. New generation clinical PET/CT can be used for simultaneous imaging of multiple small animals in experiments requiring high throughput and where a dedicated small animal PET system is not available. (orig.)

  3. Clinical application of dual-source CT in the diagnosis of ALCAPA

    Institute of Scientific and Technical Information of China (English)

    程召平

    2014-01-01

    Objective To explore the clinical usefulness of anomalous origin of left coronary artery from the pulmonary artery(ALCAPA)by dual-source CT(DSCT)angiography.Methods A total of 10 patients(mean age5.1±5.0 yrs,age range 0.2-15 yrs;male 5)withALCAPA who underwent DSCT angiography and echocardiography were retrospectively included.Surgery was performed in 7 patients,and conventional cardiac angiography(CCA)in 4 patients.The subjective image quality was evaluated on a

  4. Comparison of application value between spiral CT and DR plain film in diagnosis of acetabulum fracture%对比螺旋 CT 与 DR 平片在髋臼骨折诊断中的应用价值

    Institute of Scientific and Technical Information of China (English)

    刘金全; 海忠; 崔凌; 郭锐

    2015-01-01

    目的:对比螺旋 CT 与 DR 平片在髋臼骨折诊断中的应用价值。方法58例髋臼骨折患者作为研究对象。所有患者均经手术证实为髋臼骨折,术前行螺旋 CT 与 DR 摄影,其中螺旋 CT 采用多平面重建(MPR)、三维表面重建(SSD)、容积重建(VR)等三维重建技术进行图像后处理,对比两种检查方案的诊断结果。结果CT 确诊髋臼骨折55例,高疑骨折3例, DR 确诊骨折42例,高疑8例,无骨折8例,两组确诊结果比较,差异有统计学意义(P<0.05);CT 诊断准确率更高。结论螺旋 CT 三维重建技术具有扫描快速、成像清晰的特点,在髋臼骨折诊断中具有重要的应用价值,较常规 DR 平片具有更高的确诊率,同时可有效评估患者骨折病情,为手术治疗方案提供指导。%Objective To compare the application value between spiral CT and DR plain film in diagnosis of acetabulum fracture. Methods There were 58 patients with acetabulum fracture as study subjects, and they were all diagnosed by operation. They received spiral CT and DR filming before operation. 3D reconstruction by multiple planar reconstruction (MPR), surface shading display (SSD), and volume reconstruction (VR) were applied for image postprocessing in spiral CT. Diagnosis results of the two examination methods were compared. Results CT showed 55 diagnosed acetabulum fracture cases and 3 highly suspected fracture cases. DR showed 42 diagnosed fracture cases, 8 highly suspected cases, and 8 cases without fracture. The difference between diagnosis results of the two groups had statistical significance (P<0.05). CT provided more accuracy in diagnosis. Conclusion Spiral CT 3D reconstruction method has advantages of quick scanning and clear imaging, and it contains important application value in diagnosis of acetabulum fracture. It provides higher diagnosis rate than common DR plain film with effective assessment of fracture condition, and it can

  5. SPECT-CT and PET-CT progress in the research of computer analysis method

    Directory of Open Access Journals (Sweden)

    Jingang Guo

    2015-04-01

    Full Text Available The development of multimodal imaging equipment is milestone in the development of imaging, after the PET-CT, American GE company launched a Discovery 670 NM/CT, CT and SPECT, the organic integration of the formation of SPECT-CT new molecular medical imaging equipment, with SPECT, CT and PET-CT is getting more and more widely attention and application, many of SPECT-CT and PET-CT image analysis computer method arises at the historic moment, getting increasing attention of the clinical and imaging science. The paper carried on the detailed description of the SPECT-CT and PET-CT computer analysis method.

  6. Spectral CT: Clinical application and research progress%能谱CT的临床应用与研究进展

    Institute of Scientific and Technical Information of China (English)

    雷立昌; 陈建宇

    2013-01-01

    多排螺旋CT技术的广泛应用及计算机后处理技术的不断发展,使能谱CT成像从理论走向实践.能谱CT从球管和探测器等方面进行革新,尽可能同时、同相位获得两个不同能量水平的图像,从而重建出40~140 keV的高清单能量图像、多种基础物质密度图像、虚拟图像以及特异能谱曲线,为疾病的早期发现、定性甚至定量诊断提供可靠依据,为临床实践和科研提供更为广阔的发展空间.%Advances in multi-detector technology and computer processing technology have made spectral CT imaging possible. On the basis of the improvement of X-ray tubes and X-ray detectors, spectral CT can obtain two images at different levels of energy at the same time and at the same phase to reconstruct high-definition and monochromatic images from 40 keV to 140 keV and even generate 3-materials decomposition images, virtual non-contrast images and specific spectrum curve. These imaging technologies provide reliable information to diagnose disease earlier and more accurately. Spectral CT is a promising technique with clinical application potential.

  7. Flat-detector computed tomography with intravenous contrast material application in experimental aneurysms: comparison with multislice CT and conventional angiography.

    Science.gov (United States)

    Struffert, Tobias; Doelken, Marc; Adamek, Edyta; Schwarz, Marc; Engelhorn, Tobias; Kloska, Stephan; Ott, Sabine; Doerfler, Arnd

    2010-05-01

    Despite limited soft tissue resolution flat-detector computed tomography (FD-CT) provides substantial superior spatial resolution in comparison with multislice computed tomography (MS-CT). This may add value in the visualization of small vascular structures if intravenous contrast application leads to substantial opacification and visibility of intracranial vessels or aneurysms. To evaluate the feasibility of visualization of vascular structures by FD-CT angiography (FD-CTA) after intravenous contrast injection compared with MS-CTA and intra-arterial digital subtracted angiography (IADSA) in an animal model. Aneurysms were created in the right common carotid artery in six New Zealand White Rabbits using the elastase technique. Imaging was performed using FD-CTA, MS-CTA (injection of 1 ml/kg body weight) and IADSA. Anonymized volume rendering reconstruction (VRT), maximum intensity projection (MIP), and multiplanar reconstruction (MPR) images were reconstructed and evaluated by two experienced reviewers for aneurysm geometry and vascular structure anatomy using standard tools of a dedicated workstation. Aneurysms could be successfully created in all animals. Measurements of aneurysm geometry (aneurysm height, width, neck width) and vascular structures (brachiocephalic trunk, carotid artery diameter and plane) were nearly identical in all three modalities. Intra- and inter-observer correlations of the different parameters showed high r values between 0.83 and 0.99. Our results show the feasibility of FD-CTA in comparison with MS-CTA and IADSA in an animal model. Despite limited soft tissue resolution, opacification of vascular structures with sufficient contrast to the surrounding structures was possible in all animals. Vascular structures appeared better delineated in FD-CTA than in MS-CTA, probably due to the superior spatial resolution.

  8. Application of time sampling in brain CT perfusion imaging for dose reduction

    Science.gov (United States)

    Lee, S. H.; Kim, J. H.; Kim, K. G.; Park, S. J.; Im, Jung Gi

    2007-03-01

    The purpose of this study is to determine a stable sampling rate not to be affected by sampling shift for reducing radiation exposure with time sampling and interpolation in cerebral perfusion CT examination. Original images were obtained every 1 second for 40 time series from 3 patients, respectively. Time sampling was performed with sampling intervals (SI) from 2 to 10 seconds. Sampling shift was applied from +1 to SI-1 for each sampling rate. For each patient, 30 tissue concentration time-course data were collected, and arterial input curves were fitted by gamma-variate function. The sinc function was introduced for interpolation. Deconvolution analysis based on SVD was performed for quantifying perfusion parameters. The perfusion values through time-varying sampling and interpolation were statistically compared with the original perfusion values. The mean CBF values with increase of sampling interval and shift magnitude from the collected data had a wider fluctuation pattern centering around the original mean CBF. The mean CBV values had a similar tendency to the mean CBF values, but a relatively narrower deviation. The mean MTT values were fluctuated reversely to the trend of the mean CBF values. The stable sampling interval for quantifying perfusion parameters with lower radiation exposure was statistically acceptable up to 4 seconds. These results indicate that sampling shift limits sampling rate for acquiring acceptable perfusion values. This study will help in selecting more reasonable sampling rate for low-radiation-dose CT examination.

  9. PET/CT in cancer research: from preclinical to clinical applications.

    Science.gov (United States)

    Del Vecchio, S; Zannetti, A; Fonti, R; Iommelli, F; Pizzuti, L M; Lettieri, A; Salvatore, M

    2010-01-01

    The identification of genetic and biochemical mechanisms underlying tumor growth and progression along with the unraveling of human genoma provided a plethora of new targets for cancer detection, treatment and monitoring. Simultaneously, the extraordinary development of a number of imaging technologies, including hybrid systems, allowed the visualization of biochemical, molecular and physiological aberrations linked to underlying mutations in a given tumor. In vivo evaluation of complex biological processes such as proliferation, apoptosis, angiogenesis, metastasis, gene expression, receptor-ligand interactions, transport of substrates and metabolism of nutrients in human cancers is feasible using PET/CT and radiolabeled molecular probes. Some of these compounds are in preclinical phases of evaluation whereas others have been already applied in clinical settings. Here we provide prominent examples on how some biological processes and target expression can be visualized by PET/CT in animal tumor models and cancer patients for the noninvasive detection of well-known markers of tumor aggressiveness, invasiveness and resistance to treatment and for the evaluation of tumor response to therapy.

  10. A Multiatlas Segmentation Using Graph Cuts with Applications to Liver Segmentation in CT Scans

    Directory of Open Access Journals (Sweden)

    Carlos Platero

    2014-01-01

    Full Text Available An atlas-based segmentation approach is presented that combines low-level operations, an affine probabilistic atlas, and a multiatlas-based segmentation. The proposed combination provides highly accurate segmentation due to registrations and atlas selections based on the regions of interest (ROIs and coarse segmentations. Our approach shares the following common elements between the probabilistic atlas and multiatlas segmentation: (a the spatial normalisation and (b the segmentation method, which is based on minimising a discrete energy function using graph cuts. The method is evaluated for the segmentation of the liver in computed tomography (CT images. Low-level operations define a ROI around the liver from an abdominal CT. We generate a probabilistic atlas using an affine registration based on geometry moments from manually labelled data. Next, a coarse segmentation of the liver is obtained from the probabilistic atlas with low computational effort. Then, a multiatlas segmentation approach improves the accuracy of the segmentation. Both the atlas selections and the nonrigid registrations of the multiatlas approach use a binary mask defined by coarse segmentation. We experimentally demonstrate that this approach performs better than atlas selections and nonrigid registrations in the entire ROI. The segmentation results are comparable to those obtained by human experts and to other recently published results.

  11. Motion Artifacts of Ascending Aorta:CT Features and Elimination Methods%升主动脉搏动样伪影的螺旋CT表现及其消除措施

    Institute of Scientific and Technical Information of China (English)

    朱玉春; 王建良; 吴志娟; 周伟; 张怀信

    2013-01-01

    目的 探讨升主动脉搏动样伪影的单层和多层螺旋CT表现,及其运用心电门控技术进行消除.方法 搜集短期内(<1个月)分别进行单层和多层螺旋CT扫描患者资料50例,观察其主动脉CT图像,分别统计升主动脉搏动样伪影的检出率,及其发生部位、宽度、长度、边界是否清楚及伪影的连续性,并进行对照研究.其中20例同期进行心电门控技术冠状动脉扫描,调取其冠状动脉积分平扫图像观察升主动脉搏动样伪影的显示情况,并进行对照研究.结果 50例患者升主动脉搏动性伪影在单层和多层螺旋CT图像上的显示率分别为74.0%和80.0%,其中假内膜片样伪影显示率均较高,以左前壁和右后壁相对多见.通过统计分析升主动脉搏动性伪影的宽度(t=0.198)、长度(t=1.793)、伪影的边界清晰(X2=0.005)和连续性中断征象(X2=0.956),在单层和多层螺旋CT上差异均无统计学意义(P>0.05).其中20例同期进行多层螺旋CT心电门控技术冠脉平扫,对照其胸部平扫图像,有50%(10/20)的伪影被消除.结论 升主动脉搏动样伪影的单层和多层螺旋CT显示率均较高,差异性不明显,利用心电门控技术可以有效减少伪影的出现.%Objective To analyze helical CT manifestations of motion artifacts of ascending aorta, and to eliminate artifacts with electrocardiographic gating techniques. Methods Fifty patients underwent helical CT (single and multi slice CT ) scan. The detection rate, locations, width, length, boundary and continuity of the artifacts were evaluated by two investigators. On the other hand, 20 patients underwent multi slice helical CT scan using electrocardiographic gating techniques, characteristics of motion artifacts were recorded and compared. Results In 50 patients, the detection rate of motion artifacts on single slice and multi slice helical CT images were 74.0% and 80.0% respectively. among them, false internal flap artifact was

  12. Nanoparticle-based CT imaging technique for longitudinal and quantitative stem cell tracking within the brain: application in neuropsychiatric disorders.

    Science.gov (United States)

    Betzer, Oshra; Shwartz, Amit; Motiei, Menachem; Kazimirsky, Gila; Gispan, Iris; Damti, Efrat; Brodie, Chaya; Yadid, Gal; Popovtzer, Rachela

    2014-09-23

    A critical problem in the development and implementation of stem cell-based therapy is the lack of reliable, noninvasive means to image and trace the cells post-transplantation and evaluate their biodistribution, final fate, and functionality. In this study, we developed a gold nanoparticle-based CT imaging technique for longitudinal mesenchymal stem cell (MSC) tracking within the brain. We applied this technique for noninvasive monitoring of MSCs transplanted in a rat model for depression. Our research reveals that cell therapy is a potential approach for treating neuropsychiatric disorders. Our results, which demonstrate that cell migration could be detected as early as 24 h and up to one month post-transplantation, revealed that MSCs specifically navigated and homed to distinct depression-related brain regions. We further developed a noninvasive quantitative CT ruler, which can be used to determine the number of cells residing in a specific brain region, without tissue destruction or animal scarification. This technique may have a transformative effect on cellular therapy, both for basic research and clinical applications.

  13. Automatic aorta segmentation and valve landmark detection in C-arm CT: application to aortic valve implantation.

    Science.gov (United States)

    Zheng, Yefeng; John, Matthias; Liao, Rui; Boese, Jan; Kirschstein, Uwe; Georgescu, Bogdan; Zhou, S Kevin; Kempfert, Jörg; Walther, Thomas; Brockmann, Gernot; Comaniciu, Dorin

    2010-01-01

    C-arm CT is an emerging imaging technique in transcatheter aortic valve implantation (TAVI) surgery. Automatic aorta segmentation and valve landmark detection in a C-arm CT volume has important applications in TAVI by providing valuable 3D measurements for surgery planning. Overlaying 3D segmentation onto 2D real time fluoroscopic images also provides critical visual guidance during the surgery. In this paper, we present a part-based aorta segmentation approach, which can handle aorta structure variation in case that the aortic arch and descending aorta are missing in the volume. The whole aorta model is split into four parts: aortic root, ascending aorta, aortic arch, and descending aorta. Discriminative learning is applied to train a detector for each part separately to exploit the rich domain knowledge embedded in an expert-annotated dataset. Eight important aortic valve landmarks (three aortic hinge points, three commissure points, and two coronary ostia) are also detected automatically in our system. Under the guidance of the detected landmarks, the physicians can deploy the prosthetic valve properly. Our approach is robust under variations of contrast agent. Taking about 1.4 seconds to process one volume, it is also computationally efficient.

  14. CT and MRI assessment and characterization using segmentation and 3D modeling techniques: applications to muscle, bone and brain

    Directory of Open Access Journals (Sweden)

    Paolo Gargiulo

    2014-03-01

    Full Text Available This paper reviews the novel use of CT and MRI data and image processing tools to segment and reconstruct tissue images in 3D to determine characteristics of muscle, bone and brain.This to study and simulate the structural changes occurring in healthy and pathological conditions as well as in response to clinical treatments. Here we report the application of this methodology to evaluate and quantify: 1. progression of atrophy in human muscle subsequent to permanent lower motor neuron (LMN denervation, 2. muscle recovery as induced by functional electrical stimulation (FES, 3. bone quality in patients undergoing total hip replacement and 4. to model the electrical activity of the brain. Study 1: CT data and segmentation techniques were used to quantify changes in muscle density and composition by associating the Hounsfield unit values of muscle, adipose and fibrous connective tissue with different colors. This method was employed to monitor patients who have permanent muscle LMN denervation in the lower extremities under two different conditions: permanent LMN denervated not electrically stimulated and stimulated. Study 2: CT data and segmentation techniques were employed, however, in this work we assessed bone and muscle conditions in the pre-operative CT scans of patients scheduled to undergo total hip replacement. In this work, the overall anatomical structure, the bone mineral density (BMD and compactness of quadriceps muscles and proximal femoral was computed to provide a more complete view for surgeons when deciding which implant technology to use. Further, a Finit