WorldWideScience

Sample records for mtr-pool type research

  1. A model for the analysis of loss of decay heat removal during loss of coolant accident in MTR pool type research reactors

    Energy Technology Data Exchange (ETDEWEB)

    Bousbia-salah, Anis [Dipartimento di Ingegneria Meccanica, Nucleari e della Produzione, Facolta di Ingegneria, Universita di Pisa, Via Diotisalvi, 2, 56126 Pisa (Italy)]. E-mail: b.salah@ing.unipi.it; Meftah, Brahim [Division Reacteur - Centre de Recherche Nucleaire Draria (CRND), BP 43 Sebala DRARIA - Algiers (Algeria); Hamidouche, Tewfik [Laboratoire des Analyses de Surete, Centre de Recherche Nucleaire d' Alger (CRNA), 02 Boulevard Frantz Fanon, B.P. 399, 16000 Algiers (Algeria)]. E-mail: thamidouche@comena-dz.org; Si-Ahmed, El Khider [Laboratoire des Ecoulements Polyhpasiques, Universite des Sciences et de la Technologie d' Alger, Algiers (Algeria)

    2006-03-15

    During a loss of coolant accident leading to total emptying of the reactor pool, the decay heat could be removed through air natural convection. However, under partial pool emptying the core is partially submerged and the coolant circulation inside the fuel element could no more be possible. Under such conditions, a core overheat takes place, and the thermal energy is essentially diffused from the core to its periphery by combined thermal radiation and conduction. In order to predict fuel element temperature evolution under such conditions a mathematical model is performed. The model is based on a 3D geometry and takes into account a variety of core configurations including fuel elements (standard and control), reflector elements and grid plates. The homogeneous flow model is used and the fluid conservation equations are solved using a semi-implicit finite difference method. Preliminary tests of the developed model were made by considering a series of hypothetical accidents. In the current framework a loss of decay heat removal accidents in the IAEA benchmark open pool MTR-type research reactor is considered. It is shown that in the case of a low core immersion height no water boiling is observed and the fuel surface temperature rise remains below the melting point of the aluminium cladding.

  2. Types of Cancer Research

    Science.gov (United States)

    An infographic from the National Cancer Institute (NCI) describing the four broad categories of cancer research: basic research, clinical research, population-based research, and translational research.

  3. Analysis of partial and total flow blockage of a single fuel assembly of an MTR research reactor core

    Energy Technology Data Exchange (ETDEWEB)

    Adorni, Martina [Dipartimento di Ingegneria Meccanica, Nucleare e della Produzione, Facolta di Ingegneria, Universita di Pisa, Via Diotisalvi, 2-56100 Pisa (Italy)]. E-mail: martina_adorni@tin.it; Bousbia-Salah, Anis [Dipartimento di Ingegneria Meccanica, Nucleare e della Produzione, Facolta di Ingegneria, Universita di Pisa, Via Diotisalvi, 2-56100 Pisa (Italy); Hamidouche, Tewfik [Commissariat a l' Energie Atomique, Centre de Recherche Nucleaire d' Alger-Algeria, 02 Boulevard Frantz fanon, BP 399 Alger-gare (Algeria); Maro, Beniamino Di [Dipartimento di Ingegneria Meccanica, Nucleare e della Produzione, Facolta di Ingegneria, Universita di Pisa, Via Diotisalvi, 2-56100 Pisa (Italy); Pierro, Franco [Dipartimento di Ingegneria Meccanica, Nucleare e della Produzione, Facolta di Ingegneria, Universita di Pisa, Via Diotisalvi, 2-56100 Pisa (Italy); D' Auria, Francesco [Dipartimento di Ingegneria Meccanica, Nucleare e della Produzione, Facolta di Ingegneria, Universita di Pisa, Via Diotisalvi, 2-56100 Pisa (Italy)

    2005-10-15

    The main aim of the following study is to perform a safety analysis of the IAEA 10 MW MTR Pool type Research Reactor [IAEA-TECDOC-233, 1980. IAEA Research Reactor Core Conversion from the use of high-enriched uranium to the use of low enriched uranium fuels Guidebook] under flow blockage of a single Fuel Assembly (FA) conditions. Such event was rarely investigated in the open literature notwithstanding the fat that it constitutes a severe accident that may lead to local dryout and eventually to loss of the FA integrity. The transients herein considered are related to partial and total obstruction of the cooling channel of a single Fuel Assembly of the reactor core. This study constitutes the first step of a larger work, which consists in performing a 3D simulation using the Best Estimate coupled code technique. However, as a first approach the instantaneous reactor power is derived through the point kinetic approach of the used thermal-hydraulic system code.

  4. Experimental study of flow inversion in MTR upward flow research reactors

    Energy Technology Data Exchange (ETDEWEB)

    Abdel-Hadi, Ead A. [Benha Univ., Cairo (Egypt). Shobra Faculty of Engineering; Khedr, Ahmed; Talha, Kamal Eldin Aly; Abdel-Latif, Salwa Helmy

    2014-06-15

    The core cooling of upward flow MTR pool type Research Reactor (RR) at the later stage of pump coast down is experimentally handled to clarify the effect of some operating parameters on RR core cooling. Therefore, a test rig is designed and built to simulate the core cooling loop at this stage. The core is simulated as two vertical channels, electrically heated, and extended between upper and lower plenums. Two elevated tanks filled with water are connected to the two plenums. The first one constitutes a left branch, connected to the lower plenum, and is electrically heated to simulate the core return pipe. The second one constitutes the right branch, connected to the upper plenum, and is cooled by refrigerant circuit to simulate the reactor pool. Channel coolant and wall temperatures at different power and branch temperatures are measured, registered and analyzed. The results show that at this stage of core cooling two cooling loops are established; an internal circulation loop between the channels dominated by the difference in channel's power and an external circulation loop between the branches dominated by the temperature difference between branches. Also, there is a double inversion in core flow, upward-downward-upward flow. This double inversion increases largely the channel's wall temperature. Complementary safety analysis to evaluate this phenomenon must be performed. (orig.)

  5. Validation of RELAP5 model of experimental test rig simulating the natural convection in MTR research reactors

    Energy Technology Data Exchange (ETDEWEB)

    Khedr, A.; Abdel-Latif, Salwa H. [Nuclear and Radiological Regulatory Authority, Cairo (Egypt); Abdel-Hadi, Eed A. [Benha Univ., Cairo (Egypt). Shobra Faculty of Engineering; D' Auria, F. [Pisa Univ. (Italy)

    2016-03-15

    In an attempt to understand the built-up of natural circulation in MTR pool type upward flow research reactors after loss of power, an experimental test rig was built to simulate the loop of natural circulation in MTR reactors. The test rig consisting of two vertically oriented branches, in one of them the core is simulated by two rectangular, electrically heated, parallel channels. The other branch simulates the part of the return pipe that participates in the development of core natural circulation. In the first phase of the work, many experimental runs at different conditions of channel's power and branch's initial temperatures are performed. The channel's coolant and surface temperatures were measured. The measurements and their interpretation were published by the first three authors. In the present work the thermal hydraulic behavior of the test rig is complemented by theoretical analysis using RELAP5 Mod 3.3 system code. The analysis consisting of two parts; in the first part RELAP5 model is validated against the measured values and in the second part some of the other not measured hydraulic parameters are predicted and analyzed. The test rig is typically nodalized and an input dick is prepared. In spite of the low pressure of the test rig, the results show that RELAP5 qualitatively predicts the thermal hydraulic behaviour and the accompanied phenomenon of flow inversion of such facilities. Quantitatively, there is a difference between the predicted and measured values especially the channel's surface temperature. This difference may be return to the uncertainties in initial conditions of experimental runs, the position of the thermocouples which buried inside the heat structure, and the heat transfer package in RELAP5.

  6. Linking sustainability research to intervention types.

    Science.gov (United States)

    Scheirer, Mary Ann

    2013-04-01

    Researchers, funders, and managers of health programs and interventions have become concerned about their long-term sustainability. However, most research about sustainability has not considered the nature of the program to be sustained. Health-related interventions may differ in their likelihood of sustainability and in the factors likely to influence continuation. I suggest a framework for analyzing the sustainability of 6 types of interventions: (1) those implemented by individual providers; (2) programs requiring coordination among multiple staff; (3) new policies, procedures, or technologies; (4) capacity or infrastructure building; (5) community partnerships or collaborations; and (6) broad-scale system change. Hypotheses for future research and strategies that program managers might use to achieve sustainability also differ by program or intervention type.

  7. Research progress of spinocerebellar ataxia type 1

    Directory of Open Access Journals (Sweden)

    Lin-wei ZHANG

    2014-05-01

    Full Text Available Spinocerebellar ataxia type 1 (SCA1 is a kind of autosomal dominant genetic neurodegenerative disorder. To date, the pathogenesis of SCA1 remains unclear. Studies in numerous SCA1 experimental models, including transgenic mice, transgenic drosophila and induced pluripotent stem cells, have shown that phosphorylation of S776 in mutant ataxin-1, molecular chaperones, ubiquitin-proteasome system and down-regulation of several components of RAS-MAPK-MSK1 pathway may involve in the pathogenesis of SCA1. In this review, the clinical and pathological features of SCA1, and the latest advances of pathogenesis, model systems and therapeutic exploration will be briefly summarized. doi: 10.3969/j.issn.1672-6731.2014.05.017

  8. 10 MW research reactor simulation using fuel plate type

    Energy Technology Data Exchange (ETDEWEB)

    Mustafa, M. El Sayed, E-mail: memmm67@yahoo.com [Reactors Department, Nuclear Researches Center, Inshas (Egypt); Shaat, M. [Reactors Department, Nuclear Researches Center, Inshas (Egypt); Kady, M. El [Mechanical Power Engineering Department, Faculty of Engineering, Al Azhar University, Cairo (Egypt)

    2016-04-15

    A computer code was established named ET-RR-1-10 to investigate the thermal hydraulic behavior of the ETRR1 (first Egyptian research reactor) research reactor when its power upgraded to 10 MW using the new fuel plate elements type. The work done include both normal and flow reduction conditions. The code modeled primary loop, secondary lop, and reactor kinetics. All code models used finite difference technique. The code results were tested against the available corresponding experimental data taken from a similar research reactor MITR (Massachusetts Institute of Technology research reactor) for the sake of code validation. The results showed good agreement, and the code can be used for thermal hydraulic calculations.

  9. Tasks of research in forensic medicine - different study types in clinical research and forensic medicine.

    Science.gov (United States)

    Madea, Burkhard; Saukko, Pekka; Musshoff, Frank

    2007-01-17

    In the last years the research output of forensic medicine has sometimes been regarded as insufficient and as of poor quality, especially when parameters as impact factors and external funding were taken into account. However, forensic medicine has different tasks compared to clinical medicine. The main difference between basic subjects, clinical and forensic medicine is not a lack of scientific efficiency in forensic medicine but is a result of the questions asked, the available methods and specific aims. In contrast to natural-scientific research, forensic science has furthermore important intersections with arts and socio-scientific disciplines. Etiologic and pathogenetic research is of only limited relevance in forensic medicine. Thus, forensic medicine is excluded from these research fields, which are mainly supported by external funding. In forensic medicine research mainly means applied research regarding findings, the probative value and reconstruction as well as examination at different points of intersection between medicine and law. Clinical types of research such as controlled randomised, prospective cross-sectional, cohort or case-control studies can only rarely be applied in forensic medicine due to the area specific research fields (e.g. thantatology, violent death, vitality, traffic medicine, analytical toxicology, hemogenetics and stain analysis). The types of studies which are successfully established in forensic medicine are comparison of methods, sensitivity studies, validation of methods, kinetic examinations etc. Tasks of research in forensic medicine and study types, which may be applied will be addressed.

  10. Basic Histopathological Methods and Breast Lesion Types for Research.

    Science.gov (United States)

    Ouyang, Nengtai; Wang, Lin

    2016-01-01

    The in situ observation on the tissues, such as histopathology, immunohistochemistry (IHC), immunofluorescence (IF), and in situ hybridization (ISH), is one of the most important methods in the biomedical scientific research. In this chapter we introduce the most often used methods-hematoxylin and eosin (H&E) and double IF staining. H&E staining is used for general morphology by which the different pathological types of breast lesions are identified. The double IF staining is often used to study the protein-protein interaction on tissues for signaling mechanisms. This chapter also includes the histopathology of primary or simplified breast lesion types that is essential for applying the above methods and the reclassification of breast cancers by molecular markers.

  11. Scientific Articles, Types of Scientific Research and Productivity in Health Sciences

    OpenAIRE

    Víctor Patricio Díaz-Narváez; Aracelis Calzadilla Núñez

    2016-01-01

    The aim of this paper is to describe different types of useful research and its importance in the formative research, research training and research itself in health sciences. It is stated that one of the sources of these rejections could be because the authors did not resolve correctly, from a methodological point of view, the concatenation between the research types, research designs, the type of problems inherent to these types and research designs; objectives and methods should be propose...

  12. Appendix 1—California plant community types represented in Forest Service research natural areas

    Science.gov (United States)

    Sheauchi Cheng

    2004-01-01

    Community types and codes (Holland 1986) are in boldface; research natural area names (with ecological survey names in parentheses, if different from the research natural area names) are in plain type.

  13. Research activity with different types of scintillation materials

    Science.gov (United States)

    Brinkmann, K.-T.; Borisevich, A.; Diehl, S.; Dormenev, V.; Houzvicka, J.; Korjik, M.; Novotny, R. W.; Zaunick, H.-G.; Zimmermann, S.

    2016-10-01

    Nowadays there is a growing interest and demand in the development of new types of scintillation materials for experimental high energy physics. Future detector developments will focus on cheap, fast, and radiation hard materials, especially for application in collider experiments. The most recent results obtained by the Giessen group in close cooperation with colleagues from different institutes will be presented. The new start of the mass production of high quality lead tungstate crystals (PbWO4, PWO) for electromagnetic calorimetry was started by the company CRYTUR (Turnov, Czech Republic). We will present a detailed progress report on the research program of lead tungstate performed in the last two years. The latest results in the development of LuAG:Ce, YAG:Ce and LYSO:Ce inorganic fibers, grown by the micro pulling down method and cut with the heated wire technique as well as new glass ceramics material BaO*2SiO2 (DSB) doped by Ce and Gd will be presented. In addition, different samples of the organic plastic scintillator EJ-260 produced by the company Eljen Technology (Sweetwater, USA) have been characterized. The study has focused on the change of performance after irradiation with 150 MeV protons up to an integral fluence of 5-1013 protons/cm2 as well as with a strong 60Co gamma-source accumulating an integral dose of 100 Gy.

  14. Empirically Grounded Construction of Types and Typologies in Qualitative Social Research

    OpenAIRE

    Susann Kluge

    2000-01-01

    In qualitative social research, there are only a few approaches in which the process of typology construction is explicated and systematised in detail; furthermore, you can find very different concepts of types like ideal types, real types, prototypes, extreme types, types of structure. Because the construction of typologies is of central importance for the qualitative social research, it is necessary to clarify the concept of types and the process of typology construction. Therefore, this ar...

  15. Identifying Faculty Types Using Peer Ratings of Teaching, Research, and Service.

    Science.gov (United States)

    Kremer, John

    1991-01-01

    A study classified 90 full-time tenure-track faculty in 1 university into 5 discrete types based on teaching, research, and service. Types include all-stars, teachers and good citizens, researchers, teachers, and uninvolved. This mix of types is seen as resulting from past administrative decisions and helps shape future decisions. (Author/MSE)

  16. Scholar-Craftsmanship: Question-Type, Epistemology, Culture of Inquiry, and Personality-Type in Dissertation Research Design

    Science.gov (United States)

    Werner, Thomas P.; Rogers, Katrina S.

    2013-01-01

    "Scholar-Craftsmanship" (SC) is a quadrant methodological framework created to help social science doctoral students construct first-time dissertation research. The framework brackets and predicts how epistemological domains, cultures of inquiries, personality indicators, and research question--types can be correlated in dissertation…

  17. Scholar-Craftsmanship: Question-Type, Epistemology, Culture of Inquiry, and Personality-Type in Dissertation Research Design

    Science.gov (United States)

    Werner, Thomas P.; Rogers, Katrina S.

    2013-01-01

    "Scholar-Craftsmanship" (SC) is a quadrant methodological framework created to help social science doctoral students construct first-time dissertation research. The framework brackets and predicts how epistemological domains, cultures of inquiries, personality indicators, and research question--types can be correlated in dissertation…

  18. DESIGN OF THE RESEARCH INSTITUTION TYPE SITE MODEL

    Directory of Open Access Journals (Sweden)

    Natalia T. Zadorozhna

    2014-01-01

    Full Text Available The description of the model of site of research institution of NAPS of Ukraine (TSRI is presented. Goals and objectives оf the TSRI model are defined. Web 2.0 theoretical base for site development is considered, as well as described information environment, TSRI internet and intranet models. There are substantiated the site structure, design and site layout for research institution of NAPS of Ukraine. The example of the website of the Institute of Information Technologies and Learning Tools of the NAPS of Ukraine based on the TSRI model is showen. The technological aspects of the TSRI model are considered. There is given the scheme of internet-intranet environment to support scientific publications on pedagogical and psychological sciences. This paper is intended to web designers, researchers and administrative staff of research institutions.

  19. Comparative research on three types of coaxial slow wave structures

    Institute of Scientific and Technical Information of China (English)

    Xiao Ren-Zhen; Liu Guo-Zhi; Chen Chang-Hua

    2008-01-01

    This paper studies three types of coaxial slow wave structures(SWSs):(1)with ripples on both the inner and outer conductors;(2)with ripples on the outer conductor and smooth on the inner one;and(3)with ripples on the inner conductor and smooth on the outer one.The frequencies,coupling impedances,time growth rates and beam-wave interaction efficiencies of the three types of coaxial SWSs are obtained by theoretical analysis.Moreover,the relativistic Cerenkov generators(RCGs)with the three types of coaxial SWSs are simulated with a fully electromagnetic particle-in-cell code,and the results verify the theoretical analysis.It is proved that the RCG with double-rippled coaxial SWS has the highest conversion efficiency and the shortest starting time.

  20. Type 2 diabetes prevention from research to practice

    NARCIS (Netherlands)

    Duijzer, G.

    2016-01-01

    INTRODUCTION Diabetes is a worldwide epidemic, causing a high disease and economic burden. Type 2 diabetes, the most common form of diabetes, is associated with overweight and obesity and an unfavourable lifestyle, including unhealthy diet and physical inactivity. Over the last two

  1. Type 2 diabetes prevention from research to practice

    NARCIS (Netherlands)

    Duijzer, G.

    2016-01-01

    INTRODUCTION Diabetes is a worldwide epidemic, causing a high disease and economic burden. Type 2 diabetes, the most common form of diabetes, is associated with overweight and obesity and an unfavourable lifestyle, including unhealthy diet and physical inactivity. Over the last two

  2. The Usefulness of Different Types of Health Research: Perspectives from a Low-Income Country

    Science.gov (United States)

    Burchett, Helen; Mayhew, Susannah H.; Lavis, John N.; Dobrow, Mark J.

    2015-01-01

    This article explores the perceived value of public health research and the types of research considered useful in Ghana. Sixty-nine decision makers, researchers and stakeholders were interviewed. A broad range of research was highly valued. Two traits were important: an applied, relevant topic and quickly produced findings. Interviewees valued…

  3. Types of study in medical research: part 3 of a series on evaluation of scientific publications.

    Science.gov (United States)

    Röhrig, Bernd; du Prel, Jean-Baptist; Wachtlin, Daniel; Blettner, Maria

    2009-04-01

    The choice of study type is an important aspect of the design of medical studies. The study design and consequent study type are major determinants of a study's scientific quality and clinical value. This article describes the structured classification of studies into two types, primary and secondary, as well as a further subclassification of studies of primary type. This is done on the basis of a selective literature search concerning study types in medical research, in addition to the authors' own experience. Three main areas of medical research can be distinguished by study type: basic (experimental), clinical, and epidemiological research. Furthermore, clinical and epidemiological studies can be further subclassified as either interventional or noninterventional. The study type that can best answer the particular research question at hand must be determined not only on a purely scientific basis, but also in view of the available financial resources, staffing, and practical feasibility (organization, medical prerequisites, number of patients, etc.).

  4. Research on a New Type of Diamond Saw Plate

    Institute of Scientific and Technical Information of China (English)

    2002-01-01

    With the developing of stone material, diamond saw pl ate is used widely, and in order to increase cutting efficiency and life-span o f diamond saw plate, there are a lot of research jobs of segment for diamond saw plate. Layered segment for diamond saw plate is to divide single segment into s everal cutting tools by its structure, then increases rock-cutting faces. For i mpregnated man-made diamond saw plate, the bonding strength of diamonds with ma trix material has great effect on its life and service....

  5. RESEARCH ANNOUNCEMENTS Helly Type Problems for Some Special Convex Polygons

    Institute of Scientific and Technical Information of China (English)

    苑立平; 丁仁

    2001-01-01

    @@In the combinatorial geometry of convex sets the question of how efficiently a family of convex sets can be pierced by points has led to various problems which may be regarded as extensions of the Helly-type problems. A family of sets is said to be n-pierceable (abbreviated as Пn) if there exists a set of n points such that each member of the family contains at least one of them. A family of sets is said to be Пnk if every subfamily of size k or less is Пn. The famous Helly theorem in combinatorial geometry asserts that for finite families of convex sets in the plane П13 implies П1. In a recent paper by M. Katchalski and D. Nashtir[a] the following conjecture of Griinbaum[2] was mentioned again:

  6. The Incidence and Types of Occupational Role Stress among University Research Administrators

    Science.gov (United States)

    Katsapis, Christine C. A.

    2012-01-01

    This study explored the types of stressors prevalent in the self-reports of university research administrators (URAs) and examined whether or not the degree or type of role stress was influenced by: a) the affiliation of their office unit within their institution, or b) their type. Randomly selected members of NCURA were invited via e-mail to…

  7. 75 FR 18034 - Defense Federal Acquisition Regulation Supplement; Research and Development Contract Type...

    Science.gov (United States)

    2010-04-08

    ... Regulation Supplement; Research and Development Contract Type Determination (DFARS Case 2006-D053) AGENCY... a major defense acquisition program (MDAP) to select the contract type for a development program... requires DoD to modify regulations regarding the determination of contract type for development programs...

  8. Convective cooling in a pool-type research reactor

    Science.gov (United States)

    Sipaun, Susan; Usman, Shoaib

    2016-01-01

    A reactor produces heat arising from fission reactions in the nuclear core. In the Missouri University of Science and Technology research reactor (MSTR), this heat is removed by natural convection where the coolant/moderator is demineralised water. Heat energy is transferred from the core into the coolant, and the heated water eventually evaporates from the open pool surface. A secondary cooling system was installed to actively remove excess heat arising from prolonged reactor operations. The nuclear core consists of uranium silicide aluminium dispersion fuel (U3Si2Al) in the form of rectangular plates. Gaps between the plates allow coolant to pass through and carry away heat. A study was carried out to map out heat flow as well as to predict the system's performance via STAR-CCM+ simulation. The core was approximated as porous media with porosity of 0.7027. The reactor is rated 200kW and total heat density is approximately 1.07+E7 Wm-3. An MSTR model consisting of 20% of MSTR's nuclear core in a third of the reactor pool was developed. At 35% pump capacity, the simulation results for the MSTR model showed that water is drawn out of the pool at a rate 1.28 kg s-1 from the 4" pipe, and predicted pool surface temperature not exceeding 30°C.

  9. Convective cooling in a pool-type research reactor

    Energy Technology Data Exchange (ETDEWEB)

    Sipaun, Susan, E-mail: susan@nm.gov.my [Malaysian Nuclear Agency, Industrial Technology Division, Blok 29T, Bangi 43200, Selangor (Malaysia); Usman, Shoaib, E-mail: usmans@mst.edu [Missouri University of Science and Technology, Nuclear Engineering, 222 Fulton Hall 301 W.14th St., Rolla 64509 MO (United States)

    2016-01-22

    A reactor produces heat arising from fission reactions in the nuclear core. In the Missouri University of Science and Technology research reactor (MSTR), this heat is removed by natural convection where the coolant/moderator is demineralised water. Heat energy is transferred from the core into the coolant, and the heated water eventually evaporates from the open pool surface. A secondary cooling system was installed to actively remove excess heat arising from prolonged reactor operations. The nuclear core consists of uranium silicide aluminium dispersion fuel (U{sub 3}Si{sub 2}Al) in the form of rectangular plates. Gaps between the plates allow coolant to pass through and carry away heat. A study was carried out to map out heat flow as well as to predict the system’s performance via STAR-CCM+ simulation. The core was approximated as porous media with porosity of 0.7027. The reactor is rated 200kW and total heat density is approximately 1.07+E7 Wm{sup −3}. An MSTR model consisting of 20% of MSTR’s nuclear core in a third of the reactor pool was developed. At 35% pump capacity, the simulation results for the MSTR model showed that water is drawn out of the pool at a rate 1.28 kg s{sup −1} from the 4” pipe, and predicted pool surface temperature not exceeding 30°C.

  10. Guidelines for cost control and analysis of cost-type research and development contracts

    Science.gov (United States)

    Sibbers, C. W.

    1981-01-01

    The cost information which should be obtained from a contractor(s) on a major, cost type research and development contract(s), and the analyses and effective use of these data are discussed. Specific type(s) of information which should be required, methods for analyzing such information, and methods for effectively using the results of such analyses to enhance NASA contract and project management are included. The material presented is based primarily on the principal methods which have been effectively used in the management of major cost type research and development contracts.

  11. Research of the Resistance of Contact Welding Joint of R65 Type Rail

    Directory of Open Access Journals (Sweden)

    Kęstutis Dauskurdis

    2015-03-01

    Full Text Available In the article the R65 type rail joints that were welded by resistance welding are analysed. Survey methodology of the research consists of the following parts: visual inspection of welded joint, ultrasonic rail inspection, hardness test of upper part of the rail, fusion area research, the measurement hardness test of heat-softened area, the measurement microhardness test, microstructure research of the welded joint, impact strength experiments, chemical analysis of welded joint, wheel-rail interaction research using the finite element method (FEM. The results of the research are analysed and the quality of weld is evaluated. The conclusion is based on the results of this research.

  12. Mimic-biology research on self-recovering mechanism of cavity-type crack

    Institute of Scientific and Technical Information of China (English)

    YUAN; Chaolong; (袁朝龙); ZHONG; Yuexian; (钟约先); MA; Qingxian; (马庆贤); CAO; Qixiang; (曹起骧)

    2002-01-01

    Modeling method was used to research the recovering law of inner cavity-type cracks during the processes of high-temperature plastic deformation. It was found that the self-recovering of cavity-type fault was similar to the self-healing of wound of skin and fracture. The self-recovering process of cavity-type fault was investigated according to the rule of self-healing of wound in human body. The recrystallization mechanism of self-recovering of cavity-type fault was discovered. A new method is presented to study the self-recovering mechanism of cavity-type cracks.

  13. Flight investigation of piloting techniques and crosswind limitations using a research type crosswind landing gear

    Science.gov (United States)

    Fisher, B. D.; Deal, P. L.; Champine, R. A.; Patton, J. M., Jr.

    1979-01-01

    A research-type crosswind landing gear was tested in a flight program which used a light STOL transport in strong crosswind conditions. The research-type crosswind landing gear used enabled the airplane to land to crosswinds up to a magnitude of 25 to 30 knots. Three modes of landing-gear operation were investigated: preset, automatic, and castor (passive self-alignment). Actual test data and histograms are given for the 195 'visual flight rules' crosswind landings made.

  14. Considerations of Administrative Licensure, Provider Type, and Leadership Quality: Recommendations for Research, Policy, and Practice

    Science.gov (United States)

    Hackmann, Donald G.

    2016-01-01

    This article reviews U.S. administrative licensure regulations, focusing on type of school leader licensure, provider types, and leadership quality. Licensure obtained through university-based and alternative routes is examined. Due to limited research on alternative school administrative licensure, regulations in medicine, psychology,…

  15. The Danish Centre for Strategic Research in Type 2 Diabetes (DD2) study

    DEFF Research Database (Denmark)

    Thomsen, Reimar Wernich; Nielsen, Jens Steen; Ulrichsen, Sinna Pilgaard

    2012-01-01

    This paper provides an overview of the baseline data collected in the nationwide Danish Centre for Strategic Research in Type 2 Diabetes (DD2) project. The paper presents descriptive data from the first 580 patients enrolled in the DD2. The DD2 database will contain detailed interview data...... database represents a valuable source for outcome studies in type 2 diabetes....

  16. Research on Precaution and Detection Technology for Flow Blockage of Plate-type Fuel Element in Research Reactors

    Institute of Scientific and Technical Information of China (English)

    DING; Li; QIAO; Ya-xin; ZHANG; Nian-peng; LUO; Bei-bei; HUA; Xiao; JIA; Shu-jie; YAN; Hui-yang

    2013-01-01

    The main aim of this study is to offer the technical support for safety operation and management of research reactors using plate-type fuel assemblies in China,which is performed from analysis of precaution measures for flow blockage and detection methods of accidents.Study shows that most accidents were induced by in-core foreign objects and the swelling of fuel

  17. Research Elements: new article types by Elsevier to facilitate reproducibility in science

    Science.gov (United States)

    Zudilova-Seinstra, Elena; van Hensbergen, Kitty; Wacek, Bart

    2016-04-01

    When researchers start to make plans for new experiments, this is the beginning of a whole cycle of work, including experimental designs, tweaking of existing methods, developing protocols, writing code, collecting and processing experimental data, etc. A large part of this very useful information rarely gets published, which makes experiments difficult to reproduce. The same holds for experimental data, which is not always provided in a reusable format and lacks descriptive information. Furthermore, many types of data, such as a replication data, negative datasets or data from "intermediate experiments" often don't get published because they have no place in a research journal. To address this concern, Elsevier launched a series of peer-reviewed journal titles grouped under the umbrella of Research Elements (https://www.elsevier.com/books-and-journals/research-elements) that allow researchers to publish their data, software, materials and methods and other elements of the research cycle in a brief article format. To facilitate reproducibility, Research Elements have thoroughly thought out submission templates that include all necessary information and metadata as well as peer-review criteria defined per article type. Research Elements can be applicable to multiple research areas; for example, a number of multidisciplinary journals (Data in Brief, SoftwareX, MethodsX) welcome submissions from a large number of subject areas. At other times, these elements are better served within a single field; therefore, a number of domain-specific journals (e.g.: Genomics Data, Chemical Data Collections, Neurocomputing) support the new article formats, too. Upon publication, all Research Elements are assigned with persistent identifiers for direct citation and easy discoverability. Persistent identifiers are also used for interlinking Research Elements and relevant research papers published in traditional journals. Some Research Elements allow post-publication article updates

  18. 77 FR 16868 - Quality Verification for Plate-Type Uranium-Aluminum Fuel Elements for Use in Research and Test...

    Science.gov (United States)

    2012-03-22

    ... COMMISSION Quality Verification for Plate-Type Uranium-Aluminum Fuel Elements for Use in Research and Test...-Type Uranium-Aluminum Fuel Elements for Use in Research and Test Reactors,'' is temporarily identified... verifying the quality of plate-type uranium-aluminum fuel elements used in research and test reactors (RTRs...

  19. 78 FR 33132 - Quality Verification for Plate-Type Uranium-Aluminum Fuel Elements for Use in Research and Test...

    Science.gov (United States)

    2013-06-03

    ... COMMISSION Quality Verification for Plate-Type Uranium-Aluminum Fuel Elements for Use in Research and Test... Verification for Plate-Type Uranium-Aluminum Fuel Elements for Use in Research and Test Reactors.'' This guide... plate-type uranium-aluminum fuel elements used in research and test reactors (RTRs). ADDRESSES: Please...

  20. Deriving the Properties of Object Types for Research Data Relation Model

    Directory of Open Access Journals (Sweden)

    Suntae Kim

    2013-06-01

    Full Text Available In this study, the properties of the object types required to describe the relationship among research data resources, which may be generated during the life cycle of the research, are derived. The properties of Fedora Commons and DSpace, which are open source software used for resource management, and schema properties published in DataCite were analyzed. Based on relation names of Fedora Commons, nine new relation names were derived. Thirty-eight object type properties consolidating the target properties of the analysis were derived. The result of this study can be used as basic material for crosswalk research studies of object type relation terms to ensure interoperability among the systems.

  1. Implementation of integrated care for type 2 diabetes: a protocol for mixed methods research

    Directory of Open Access Journals (Sweden)

    Loraine Busetto

    2014-12-01

    Full Text Available Introduction: While integrated care for diabetes mellitus type 2 has achieved good results in terms of intermediate clinical and process outcomes, the evidence-based knowledge on its implementation is scarce, and insights generalisable to other settings therefore remain limited.Objective: This study protocol provides a description of the design and methodology of a mixed methods study on the implementation of integrated care for type 2 diabetes. The aim of the proposed research is to investigate the mechanisms by which and the context in which integrated care for type 2 diabetes has been implemented, which outcomes have been achieved and how the context and mechanisms have affected the outcomes.Methods: This article describes a convergent parallel mixed methods research design, including a systematic literature review on the implementation of integrated care for type 2 diabetes as well as a case study on two Dutch best practices on integrated care for type 2 diabetes.Discussion: The implementation of integrated care for diabetes type 2 is an under-researched area. Insights from this study could be applied to other settings as well as other chronic conditions to strengthen the evidence on the implementation of integrated care.

  2. Implementation of integrated care for type 2 diabetes: a protocol for mixed methods research

    Directory of Open Access Journals (Sweden)

    Loraine Busetto

    2014-12-01

    Full Text Available Introduction: While integrated care for diabetes mellitus type 2 has achieved good results in terms of intermediate clinical and process outcomes, the evidence-based knowledge on its implementation is scarce, and insights generalisable to other settings therefore remain limited. Objective: This study protocol provides a description of the design and methodology of a mixed methods study on the implementation of integrated care for type 2 diabetes. The aim of the proposed research is to investigate the mechanisms by which and the context in which integrated care for type 2 diabetes has been implemented, which outcomes have been achieved and how the context and mechanisms have affected the outcomes. Methods: This article describes a convergent parallel mixed methods research design, including a systematic literature review on the implementation of integrated care for type 2 diabetes as well as a case study on two Dutch best practices on integrated care for type 2 diabetes. Discussion: The implementation of integrated care for diabetes type 2 is an under-researched area. Insights from this study could be applied to other settings as well as other chronic conditions to strengthen the evidence on the implementation of integrated care.

  3. NEW TYPES OF IEC APPLICATIONS AND LATEST RESEARCH ON REDUCING USER FATIGUE

    OpenAIRE

    Takagi, Hideyuki

    2008-01-01

    We introduce our recent topics of interactive evolutionary computation (IEC) research. First, we introduce new types of IEC research unlike normal IEC-based system optimization: (a) estimation of IEC user's psychological scale or mental situation by analyzing the outputs of the system optimized by the user, (b) Extended IEC that optimizes a target system using IEC user's physiological data, and (c) IEC combined with evolutionary multi-objective optimization. Secondly, we describe how to reali...

  4. Different types of distrust in clinical research among whites and African Americans.

    Science.gov (United States)

    Durant, Raegan W; Legedza, Anna T; Marcantonio, Edward R; Freeman, Marcie B; Landon, Bruce E

    2011-02-01

    African Americans are thought to be more distrustful of clinical research compared to elderly whites, but it is unknown whether specific types of distrust in clinical research, such as interpersonal or societal distrust, vary according to race. The primary objective was to identify racial differences in interpersonal or societal distrust in clinical research among African Americans and whites. Seven hundred seventy-six older African Americans and whites were surveyed about their interpersonal and societal distrust using a 7-item index of distrust in clinical research. We combined the 2 societal distrust items into a societal distrust subscale. We also assessed trust in primary care physicians, access to care, health/functional status, previous exposure to clinical research, awareness of the Tuskegee Syphilis Study, perceived discrimination in health care, and sociodemographic characteristics. High societal distrust was more common among African Americans compared to whites (21% vs 7% in the top quartile of the societal distrust, p type of distrust in clinical research may warrant assessing specific types of distrust separately among racially diverse populations in future studies.

  5. Type-A Behavior, Gender, and Job Satisfaction: A Research on Instructors

    Science.gov (United States)

    Yazici, Hikmet; Altun, Fatma

    2013-01-01

    There has been some research which investigates the relationship between gender, different personality traits, and job satisfaction in the field of behavioral sciences. The aim of this study is to examine the difference between male and female instructors' job satisfaction and to investigate the predict level of job satisfaction by Type-A…

  6. Development of a Monolithic Research Reactor Fuel Type at Argonne National Laboratory

    Energy Technology Data Exchange (ETDEWEB)

    Clark, C.R.; Briggs, R.J.

    2004-10-06

    The Reduced Enrichment for Research and Test Reactors (RERTR) program has been tasked with the conversion of research reactors from highly enriched to low-enriched uranium (LEU). To convert several high power reactors, monolithic fuel, a new fuel type, is being developed. This fuel type replaces the standard fuel dispersion with a fuel alloy foil, which allows for fuel densities far in excess of that found in dispersion fuel. The single-piece fuel foil also contains a significantly lower interface area between the fuel and the aluminum in the plate than the standard fuel type, limiting the amount of detrimental fuel-aluminum interaction that can occur. Implementation of monolithic fuel is dependant on the development of a suitable fabrication method as traditional roll-bonding techniques are inadequate.

  7. Optimizing the use of breed types in developing country livestock production systems: a neglected research area.

    Science.gov (United States)

    Marshall, K

    2014-10-01

    Developing country livestock production systems are diverse and dynamic, and include those where existing indigenous breeds are currently optimal and likely to remain so, those where non-indigenous breed types are already in common use, and systems that are changing, such as by intensification, where the introduction of new breed types represents significant opportunities. These include opportunities to improve the livelihood of the world's poor, increase food and nutrition security and enhance environmental sustainability. At present, very little research has focused on this issue, such that significant knowledge gaps in relation to breed-change interventions remain. The purpose of this study is to raise awareness of this issue and suggests strategic research areas to begin filling these knowledge gaps. Such strategic research would include (i) assessing the impact of differing breed types in developing country livestock productions systems, from a range of viewpoints including intrahousehold livelihood benefit, food and nutrition security at different scales, and environmental sustainability; (ii) identification of specific livestock production systems within developing countries, and the type of livestock keepers within these system, that are most likely to benefit from new breed types; and (iii) identification of new breed types as candidates for in-situ testing within these systems, such as through the use of spatial analysis to identify similar production environments combined with community acceptance studies. Results of these studies would primarily assist stakeholders in agriculture, including both policy makers and livestock keepers, to make informed decisions on the potential use of new breed types. © 2014 Blackwell Verlag GmbH.

  8. An overview of NASA research on positive displacement type general aviation engines

    Science.gov (United States)

    Kempke, E. E.; Willis, E. A.

    1979-01-01

    The paper surveys the current status of the aviation positive displacement engine programs underway at the NASA Lewis Research Center. The program encompasses conventional, lightweight diesel, and rotary combustion engines. Attention is given to topics such as current production type engine improvement, cooling drag reduction, fuel injection, and experimental and theoretical combustion studies. It is shown that the program's two major technical thrusts are directed toward lean operation of current production type spark ignition engines and advanced alternative engine concepts. Finally, an Otto cycle computer model is also covered.

  9. The Danish Centre for Strategic Research in Type 2 Diabetes (DD2) study

    DEFF Research Database (Denmark)

    Beck-Nielsen, Henning; Solomon, Thomas Pj; Lauridsen, Jørgen Trankjær

    2012-01-01

    The overall aim of the Danish Centre for Strategic Research in Type 2 Diabetes (DD2) is to near-normalize metabolic control in newly diagnosed patients with type 2 diabetes (T2D) using an individualized treatment approach. We hypothesize that this will not only prevent complications and improve...... quality of life for T2D patients but also result in increased cost efficiency compared with current treatment modalities. This paper provides an overview of the expected outcomes from DD2, focusing on the two main intervention studies. The main data for the DD2 project are collected during patient...

  10. Quality of life research: types of publication output over time for cancer patients, a systematic review.

    Science.gov (United States)

    Bailey, L J; Sanson-Fisher, R; Aranda, S; D'Este, C; Sharkey, K; Schofield, P

    2010-09-01

    To examine the type of published research regarding quality of life for cancer patients over two 24-month periods: 1995-1996 and 2005-2006. A computer-based literature search was conducted using Medline. Two random samples of 120 publications identified in 1995-1996 and in 2005-2006 were coded as data-based research, reviews or programme descriptions. Data-based publications were further coded as measurement, descriptive or intervention research. Intervention publications were coded as psychosocial- or biomedical-based. Psychosocial intervention papers were coded using Cochrane Review criteria. In 1995-1996, 419 publications were identified and 1271 publications in 2005-2006. The majority of publications were data-based. The proportion of types of publications (data-based, reviews or programme description/case report categories) did not change significantly over time. Descriptive research dominated data-based publication outputs in 1995-1996 and 2005-2006. The current approach to quality of life research for cancer patients may be less than optimal for providing successful development of knowledge, improving healthcare delivery and lessening the burden of suffering.

  11. Type 2 Diabetes Research Yield, 1951-2012: Bibliometrics Analysis and Density-Equalizing Mapping.

    Directory of Open Access Journals (Sweden)

    Fiona Geaney

    Full Text Available The objective of this paper is to provide a detailed evaluation of type 2 diabetes mellitus research output from 1951-2012, using large-scale data analysis, bibliometric indicators and density-equalizing mapping. Data were retrieved from the Science Citation Index Expanded database, one of the seven curated databases within Web of Science. Using Boolean operators "OR", "AND" and "NOT", a search strategy was developed to estimate the total number of published items. Only studies with an English abstract were eligible. Type 1 diabetes and gestational diabetes items were excluded. Specific software developed for the database analysed the data. Information including titles, authors' affiliations and publication years were extracted from all files and exported to excel. Density-equalizing mapping was conducted as described by Groenberg-Kloft et al, 2008. A total of 24,783 items were published and cited 476,002 times. The greatest number of outputs were published in 2010 (n=2,139. The United States contributed 28.8% to the overall output, followed by the United Kingdom (8.2% and Japan (7.7%. Bilateral cooperation was most common between the United States and United Kingdom (n=237. Harvard University produced 2% of all publications, followed by the University of California (1.1%. The leading journals were Diabetes, Diabetologia and Diabetes Care and they contributed 9.3%, 7.3% and 4.0% of the research yield, respectively. In conclusion, the volume of research is rising in parallel with the increasing global burden of disease due to type 2 diabetes mellitus. Bibliometrics analysis provides useful information to scientists and funding agencies involved in the development and implementation of research strategies to address global health issues.

  12. Type 2 Diabetes Research Yield, 1951-2012: Bibliometrics Analysis and Density-Equalizing Mapping.

    Science.gov (United States)

    Geaney, Fiona; Scutaru, Cristian; Kelly, Clare; Glynn, Ronan W; Perry, Ivan J

    2015-01-01

    The objective of this paper is to provide a detailed evaluation of type 2 diabetes mellitus research output from 1951-2012, using large-scale data analysis, bibliometric indicators and density-equalizing mapping. Data were retrieved from the Science Citation Index Expanded database, one of the seven curated databases within Web of Science. Using Boolean operators "OR", "AND" and "NOT", a search strategy was developed to estimate the total number of published items. Only studies with an English abstract were eligible. Type 1 diabetes and gestational diabetes items were excluded. Specific software developed for the database analysed the data. Information including titles, authors' affiliations and publication years were extracted from all files and exported to excel. Density-equalizing mapping was conducted as described by Groenberg-Kloft et al, 2008. A total of 24,783 items were published and cited 476,002 times. The greatest number of outputs were published in 2010 (n=2,139). The United States contributed 28.8% to the overall output, followed by the United Kingdom (8.2%) and Japan (7.7%). Bilateral cooperation was most common between the United States and United Kingdom (n=237). Harvard University produced 2% of all publications, followed by the University of California (1.1%). The leading journals were Diabetes, Diabetologia and Diabetes Care and they contributed 9.3%, 7.3% and 4.0% of the research yield, respectively. In conclusion, the volume of research is rising in parallel with the increasing global burden of disease due to type 2 diabetes mellitus. Bibliometrics analysis provides useful information to scientists and funding agencies involved in the development and implementation of research strategies to address global health issues.

  13. New national Biobank of The Danish Center for Strategic Research on Type 2 Diabetes (DD2

    Directory of Open Access Journals (Sweden)

    Christensen H

    2012-09-01

    Full Text Available Henry Christensen,1 Jens Steen Nielsen,2 Karina Meden Sørensen,3 Mads Melbye,3 Ivan Brandslund1,41Department of Clinical Biochemistry, Vejle Hospital, Vejle, Denmark; 2The Danish Centre for Strategic Research in Type 2 Diabetes (DD2, Department of Endocrinology M, Diabetes Research Centre, Odense University Hospital, Odense, Denmark; 3Department of Epidemiology Research, Statens Serum Institut, Copenhagen, Denmark; 4Institute of Regional Health Research, University of Southern Denmark, Odense, DenmarkAbstract: Long-term storage of biological samples from patients has become increasingly important in studies of disease control and treatment. The first nationwide Danish diabetes project, ie, The Danish Center for Strategic Research in Type II Diabetes (DD2, aims to improve treatment and the long-term outcome of patients with newly diagnosed type 2 diabetes (T2D. The DD2 project includes establishment of a biobank with samples from 50,000 patients with newly diagnosed T2D. This paper describes how blood and urine samples from 10,000 patients per year are collected, handled, and stored. The biobank includes whole blood, DNA, and plasma and urine samples, all frozen at −80°C. Sampling tubes have been standardized and are sent to hospital outpatient clinics and general practitioners where samples are taken, handled, aliquoted, and returned by mail overnight in standardized cryostorage tubes. When received at the biobank, samples are frozen without further treatment. From each patient, 24 cryostorage tubes are stored. Each tube is labeled with a barcode that links the data to other information available in a clinical databank registry. When patients are enrolled in DD2, a questionnaire is filled out and a quality monitoring system ensures that patients, samples, and questionnaires can be linked together at all times. The biobank is located at Vejle Hospital and the Danish National Biobank at Statens Serum Institut. As of the end of March 2012

  14. Computational simulation of fuel burnup estimation for research reactors plate type

    Energy Technology Data Exchange (ETDEWEB)

    Santos, Nadia Rodrigues dos, E-mail: nadiasam@gmail.com [Instituto Federal de Educacao, Ciencia e Tecnologia do Rio de Janeiro (IFRJ), Paracambi, RJ (Brazil); Lima, Zelmo Rodrigues de; Moreira, Maria de Lourdes, E-mail: zrlima@ien.gov.br, E-mail: malu@ien.gov.br [Instituto de Engenharia Nuclear (IEN/CNEN-RJ), Rio de Janeiro, RJ (Brazil)

    2015-07-01

    The aim of this study is to estimate the spatial fuel burnup, through computational simulation, in two research reactors plate type, loaded with dispersion fuel: the benchmark Material Test Research - International Atomic Energy Agency (MTR-IAEA) and a typical multipurpose reactor (MR). The first composed of plates with uranium oxide dispersed in aluminum (UAlx-Al) and a second composed with uranium silicide (U{sub 3}Si{sub 2}) dispersed in aluminum. To develop this work we used the deterministic code, WIMSD-5B, which performs the cell calculation solving the neutron transport equation, and the DF3DQ code, written in FORTRAN, which solves the three-dimensional neutron diffusion equation using the finite difference method. The methodology used was adequate to estimate the spatial fuel burnup , as the results was in accordance with chosen benchmark, given satisfactorily to the proposal presented in this work, even showing the possibility to be applied to other research reactors. For future work are suggested simulations with other WIMS libraries, other settings core and fuel types. Comparisons the WIMSD-5B results with programs often employed in fuel burnup calculations and also others commercial programs, are suggested too. Another proposal is to estimate the fuel burnup, taking into account the thermohydraulics parameters and the Xenon production. (author)

  15. The Danish Centre for Strategic Research in Type 2 Diabetes (DD2)

    DEFF Research Database (Denmark)

    Thomsen, Reimar Wernich; Friborg, Søren; Nielsen, Jens Steen

    2012-01-01

    This paper provides a short overview of the Danish health care system and the organization of care for type 2 diabetes patients in Denmark. It also describes the supplementary data sources that are used for collection of baseline data in the nationwide Danish Centre for Strategic Research in Type 2...... form the basis for recruiting diabetes patients in the DD2 project, and the data sources that these providers use in clinical practice give access to important supplementary patient data. The DD2's patient-enrollment system is designed to be fast and simple, and thus only collects primary interview...... data that cannot be extracted from already existing data sources. Thus, in addition to an online DD2 questionnaire filled out by general practitioners and hospital physicians at the time of patient enrollment, supplementary data are obtained from the Danish Diabetes Database for Adults, a nationwide...

  16. The Danish Centre for Strategic Research in Type 2 Diabetes (DD2) Project

    DEFF Research Database (Denmark)

    Steffensen, Maria Charlotte; Thomsen, Reimar W; Vaag, Allan

    2012-01-01

    Here we provide an overview of the rationale and methods of a series of planned population based studies within the Danish Centre for Strategic Research in Type 2 Diabetes (DD2) Project. The project aims to support and evaluate ongoing political and administrative efforts to implement nationwide...... guidelines for maintaining metabolic control in newly diagnosed type 2 diabetes (T2D) patients to prevent diabetic complications and improve quality of life. The DD2 is designed as a prospective cohort study (collection of epidemiological data) supplemented by randomized clinical intervention trials (on...... physical exercise and individualized pharmacological treatment) and the establishment of a biobank comprised of material from a large number of newly diagnosed T2D patients. Inclusion of the majority of newly diagnosed T2D patients as they are diagnosed at their general practitioner or diabetes hospital...

  17. Research Program on Type 1 Diabetes and Youth Depression in Puerto Rico

    Science.gov (United States)

    Cumba-Avilés, Eduardo; Sáez-Santiago, Emily

    2016-01-01

    This work reviews the progress and current state of a research program on Diabetes and youth depression in Puerto Rico. Given the high depression rate, its impact in youth with Type 1 Diabetes (T1D), and the lack of interventions to target this link in an integrative way, the manual titled Cognitive-Behavioral Treatment for Depression in Adolescents with T1D was developed. After its first use in an Open Trial, we currently assess the initial efficacy of its revised version to reduce depression and improve glycemic control, self-care, and quality of life. We present its approach, and initial data on its feasibility, acceptability and potential to reduce emotional problems in T1D youth. We discuss implications of this line of research for health psychology, and its utility to model the development of interventions alike focused on other chronic illnesses.

  18. Research Program on Type 1 Diabetes and Youth Depression in Puerto Rico.

    Science.gov (United States)

    Cumba-Avilés, Eduardo; Sáez-Santiago, Emily

    2016-01-01

    This work reviews the progress and current state of a research program on Diabetes and youth depression in Puerto Rico. Given the high depression rate, its impact in youth with Type 1 Diabetes (T1D), and the lack of interventions to target this link in an integrative way, the manual titled Cognitive-Behavioral Treatment for Depression in Adolescents with T1D was developed. After its first use in an Open Trial, we currently assess the initial efficacy of its revised version to reduce depression and improve glycemic control, self-care, and quality of life. We present its approach, and initial data on its feasibility, acceptability and potential to reduce emotional problems in T1D youth. We discuss implications of this line of research for health psychology, and its utility to model the development of interventions alike focused on other chronic illnesses.

  19. An analysis of the types of recently published research in the field of cachexia.

    Science.gov (United States)

    Shewan, Louise G

    2017-01-01

    Introduction Cachexia is a common complication of many and varied chronic disease processes, yet it has received very little attention as an area of clinical research effort until recently. We sought to survey the contemporary literature on published research into cachexia to define where it is being published and the proportion of output classified into the main types of research output. Methods I searched the PubMed listings under the topic research term "cachexia" and related terms for articles published in the calendar years of 2015 and 2016, regardless of language. Searches were conducted and relevant papers extracted by two observers, and disagreements were resolved by consensus. Results There were 954 publications, 370 of which were review articles or commentaries, 254 clinical observations or non-randomised trials, 246 original basic science reports and only 26 were randomised controlled trials. These articles were published in 478 separate journals but with 36% of them being published in a core set of 23 journals. The H-index of these papers was 25 and there were 147 papers with 10 or more citations. Of the top 100 cited papers, 25% were published in five journals. Of the top cited papers, 48% were review articles, 18% were original basic science, and 7% were randomised clinical trials. Discussion This analysis shows a steady but modest increase in publications concerning cachexia with a strong pipeline of basic science research but still a relative lack of randomised clinical trials, with none exceeding 1000 patients. Research in cachexia is still in its infancy, but the solid basic science effort offers hope that translation into randomised controlled clinical trials may eventually lead to effective therapies for this troubling and complex clinical disease process.

  20. Realization of Deflection-type Bridge instruments to determine soil moisture using Research-Based Learning

    Science.gov (United States)

    Yuliza, E.; Munir, M. M.; Abdullah, M.; Khairurrijal

    2016-08-01

    It is clear that the quality of education is directly related to the quality of teachers and the teaching methods. One of the teaching methods that can improve the quality of education is research-based learning (RBL) method. In this method, students act as the center of learning while teachers become the guides that provide direction and advice. RBL is a learning method that combines cooperative learning, problem solving, authentic learning, contextual case study and inquiry approach discovery. The main goal of this method is to construct a student that can think critically, analyze and evaluate problems, and find a new science from these problems (learning by doing). In this paper, RBL is used to improve the understanding about measurement using deflection-type Bridge that is implemented in the determination of ground water changes. In general, there are three stages that have been done. Firstly the exposure stage, then the experience stage and lastly the capstone stage. The exposure stage aims to increase the knowledge and the comprehension of student about the topic through understanding the basics concepts, reviewing the literature and others. The understanding gained in the exposure stage is being used for application and analysis at the experience stage. While the final stage is the publication of research results both verbally and in writing. Based on the steps that have been conducted, it can be showed that deflection-type Bridge can be utilized in soil moisture meter.

  1. Do different psychological types look for different things in sermons? A research note

    OpenAIRE

    Francis, Leslie J.; Stone, Christopher; Robbins, Mandy

    2015-01-01

    A sample of 76 Evangelical Anglican churchgoers completed the Francis Psychological Type Scales and rated the importance that they attribute to a sermon speaking to their imagination. The data demonstrated that sermons speaking to the imagination were rated more highly by intuitive types, feeling types, and perceiving types than by sensing types, thinking types, and judging types. Different psychological types look for different things in sermons.

  2. Do different psychological types look for different things in sermons? A research note

    OpenAIRE

    FRANCIS, Leslie J.; Stone, Christopher; Robbins, Mandy

    2015-01-01

    A sample of 76 Evangelical Anglican churchgoers completed the Francis Psychological Type Scales and rated the importance that they attribute to a sermon speaking to their imagination. The data demonstrated that sermons speaking to the imagination were rated more highly by intuitive types, feeling types, and perceiving types than by sensing types, thinking types, and judging types. Different psychological types look for different things in sermons.

  3. Ranking of integration factors within supply chains of forward and backward types - recommendations from researches

    Directory of Open Access Journals (Sweden)

    Bernd Hentschel

    2015-06-01

    Full Text Available Background: Integration trends are one of main determinants of the development of modern logistics. After the period of interest focused mainly on supply chains realizing one-way flows only, at present there is a time for supply chains characterized by two-way flows, realizing at the same time both forward and backward flows. The possibility of various configurations of such chains requires identification of integration factors and determination of their influence on the results of the whole supply chain. Experiences of the science as well as the practice of supply chains show the urgent need of learning of reasons of the integration within supply chains of the two-way type.  Material and methods: The researches on modeling and simulation of integration processes within supply chains of forward and backward type were carried out in the environment of iGrafx Process 2013 for Six Sigma. The empirical material obtained in these researches was put to the statistical analysis by the used of Minitab 17. The identification of the significance of differences was made with the help of analysis of variance ANOVA. Additionally the analysis of differences in form of absolute averages was made.  The following measures are main ones for the evaluation of the integration of a supply chain of forward and backward types: cashflow, profitability, service level.  Results: 8 192 simulation experiments were made for 6 integration factors: accessibility of recycled materials, production planning, stock management, integration of transport, unification of packing materials and optimization of the material flow. Based on the analysis of the significance and values of differences, the results of the influence of each integration factor on global results of supply chains of forward and backward type were obtained. They were used to prepare the ranking of integration factors. The main factors, forming the integration shape of two-way supply chains were: stock

  4. The Danish Centre for Strategic Research in Type 2 Diabetes (DD2) study

    DEFF Research Database (Denmark)

    Nielsen, Jens Steen; Thomsen, Reimar W; Steffensen, Charlotte

    2012-01-01

    This paper aims to describe the patient enrollment system and implementation strategy for the new nationwide Danish Centre for Strategic Research in Type 2 Diabetes (DD2) project. The paper will also describe the design, current content, and pilot testing of the DD2 registration form. The challenge...... that is part of everyday clinical practice in hospital outpatient clinics and general practitioner (GP) clinics. The enrollment system is thus built on a tested, rational design where patients need only one visit and only specific limited data about physical activity, anthropometric measures, and family...... were provided and an interactive webpage was constructed. The DD2 project also involves collection of blood and urine samples from each diabetes patient, to be stored in a biobank. Clinicians may obtain the samples themselves or refer patients to the nearest clinical biochemical department. GPs have...

  5. Selecting the "right" mouse model for metabolic syndrome and type 2 diabetes research.

    Science.gov (United States)

    Leiter, Edward H

    2009-01-01

    This is not a "Methods" chapter in the traditional sense. Rather, it is an essay designed to help address one of the most frequently asked questions by investigators about to embark on a study requiring an animal model of diabetes - what is the "right" model for the reader's specific research application. Because genetic heterogeneity and the requirement for complex gene-environment interaction characterize the various mouse models of Type 2 diabetes as well as the human disease manifestations, the readers may come to share the author's conclusion that more than one model is required if the investigator is interested in knowing how broadly effective a given compound with putative therapeutic efficacy might be.

  6. Croatian banking sector research: relationship between ownership structure, concentration, owners’ type and bank performance

    Directory of Open Access Journals (Sweden)

    Igor Tomičić

    2012-12-01

    Full Text Available Banks are important financial intermediaries of any national economy, and corporate governance has an important role in banking sector; especially due to processes of the globalization and the internationalization, and also because of the sensitivity of the activities between the interest groups. The objective of this paper is to examine the relationship between ownership structure, concentration, owners’ type and bank performance. The authors made a research of banks' ownership structure using publicly available data. Using statistical tools authors discovered relationships between bank ownership structure and bank performance indicators (average asset, total asset, average equity, profit (loss before taxes, profit (loss after taxes, ROAA, ROAE. Further they discuss the relationships between ownership structure and a number of consequences for the bank performance. The authors discovered significant correlation between bank ownership structure and performance indicators variables that are described in the paper.

  7. Research of the types of applicable people and the statistical characteristics of hand vein image

    Science.gov (United States)

    Yang, Haifeng; Yang, Xiaoping; Xu, Wuchao; Yao, Shuyu; Wei, Chongchong; Qu, Huinan; Qu, Bingguang

    2014-11-01

    Hand vein image has been widely used in biological recognition, auxiliary medical and other fields. People with age, height, weight, gender differences have distinction in fat thickness of the back of hand, so the contrast and sharpness of their hand vein images are different too, which may affect the results of applications. In this paper, a hand vein image acquisition system is given and the hand vein images of people from the age of 3 to 60 are obtained in various conditions. The effect on the images caused by ages, genders, BMI (body mass index) and FMI (fat mass index) are researched and the statistical characteristics of the images are analyzed. The types of applicable people are also proposed for applications.

  8. Research and Application of New Type of High Performance Titanium Alloy

    Directory of Open Access Journals (Sweden)

    ZHU Zhishou

    2016-06-01

    Full Text Available With the continuous extension of the application quantity and range for titanium alloy in the fields of national aviation, space, weaponry, marine and chemical industry, etc., even more critical requirements to the comprehensive mechanical properties, low cost and process technological properties of titanium alloy have been raised. Through the alloying based on the microstructure parameters design, and the comprehensive strengthening and toughening technologies of fine grain strengthening, phase transformation and process control of high toughening, the new type of high performance titanium alloy which has good comprehensive properties of high strength and toughness, anti-fatigue, failure resistance and anti-impact has been researched and manufactured. The new titanium alloy has extended the application quantity and application level in the high end field, realized the industrial upgrading and reforming, and met the application requirements of next generation equipment.

  9. Commercial Application of the CTV-IV Type Catalyst for Synthesis of Vinyl Acetate Developed by Shanghai Petrochemical Research Instit

    Institute of Scientific and Technical Information of China (English)

    2008-01-01

    @@ The CTV-IV type catalyst for synthesis of vinyl acetate developed by the SINOPEC Shanghai Petrochemical Research Institute (SPRI) has been successfully applied on the #2 vinyl acetate unit at SINOPEC's Shanghai Petrochemical Company.

  10. Re-commissioning of an electron accelerator: industrial-type in research style

    Science.gov (United States)

    Ehlermann, D. A. E.; Morriseau, D.

    2002-03-01

    After 25 years of utilization in 1992, the electron linear accelerator was replaced by a modern type, CIRCE III of CGR-MeV (now Thomson-CSF). The goal had been to bring a typical industrial-style machine-source of radiation to the research institute in order to enable it to study any relevant parameter in radiation processing of food under commercial conditions. The machine should be as close in design to industrial practices, but at the same time allow for research into dosimetry and process control. As the FRCN moved to its new site, the decision was to re-install the accelerator there. At this occasion and based on the operating experiences of the recent years, several new features were introduced: the scan mode was changed from during-pulse to shot-by-shot; the bending magnet was modified from 107° to 253° (pretzel-type); the exploitable scanning width was increased from 40 to 80 cm. After this modification, the machine characteristics had to be verified. For the changed scan-mode the adjustment of pulse repetition rate, scan frequency, transport velocity, and beam cross-section in both directions, had to be established for the targeted low-dose treatments (about 100 Gy). Furthermore, the facility has now two separated beam-outlets, one for handling the prepacked materials on a transport system, the other one for bulk material handling (not yet installed) and for bremsstrahlung-mode experiments. First results with the accelerator after its transfer to the new site are reported; the radiation field characteristics after the modifications are given.

  11. Elaboration and research of planetary precessional multiplier type K-H-V

    Science.gov (United States)

    Bostan, I.; Dulgheru, V.; Ciobanu, R.

    2016-08-01

    The multiplier is an indispensable part of the micro hydropower plant and high power wind turbine. It helps to increase rotor low speeds limited by the water flow small velocity and by the relative big placement diameter of the blades that participate in the energy conversion. For example, the microhydrostation rotor's speed is (2 - 3) min'1 for water flow velocity V= (1...1,6) m/s and for blade placement diameter D = 4 m. Diversity of requirements forwarded by the beneficiaries of mechanical transmissions consists, in particular, in increasing reliability, efficiency and lifting capacity, and in reducing the mass and dimensions. It becomes more and more difficult to satisfy the mentioned demands by partial updating of traditional transmissions. The target problem can be solved with special effects by developing new types of multipliers based on precessional planetary transmissions with multiple gear, that were developed by the authors. Absolute multiplicity of precessional gear (up to 100% pairs of teeth simultaneously involved in gearing, compared to 5%-7% - in classical gearings) provides increased lifting capacity and small mass and dimensions. To mention that until now precessional planetary transmissions have been researched and applied mainly in reducers. Therefore it was necessary to carry out theoretical research to determine the geometrical parameters of the precessional gear that operates in multiplier mode. Also, it was necessary to develop new conceptual diagrams of precessional transmissions that function under multiplier regime. The majority of precessional planetary transmissions diagrams developed previously operate efficiently in reducer's regime. Depending on the structural diagram, precessional transmissions fall into two main types - K-H-V and 2K-H, from which a wide range of constructive solutions with wide kinematical and functional options that operate in multiplier regime.

  12. Fifty years of research on serotypes and mating types in Dileptus anser: A review.

    Science.gov (United States)

    Uspenskaya, Zoya I; Yudin, Alexander L

    2016-04-01

    The ciliate Dileptus anser is increasingly used as a laboratory model not only in protozoological research sensu stricto, but also in general biology. However, genetic studies of this ciliate have never been carried out, and this species is new to the comparative genetics of ciliates. This review describes the genetic experiments conducted at the Institute of Cytology of the Russian Academy of Sciences for the last 50 years. Two characters that are classical for the genetics of ciliates, serotypes and mating types were selected for analysis. The results presented do not fit into conventional genetic schemes and may have epigenetic nature. Features of this model that were revealed earlier (the simplest possible system of multiple mating types, full serial dominance of the alleles in the mat locus, the excretion of pheromones, etc.) are promising with regard to interesting comparisons of breeding systems in ciliates. The results obtained in studies of mating pheromones in D. anser have demonstrated that this model is a perspective one for further exploration of intercellular recognition in lower eukaryotes and of other related issues. Copyright © 2015 Elsevier GmbH. All rights reserved.

  13. Effects of Type and Combination of Feedback upon Conceptual Learning by Children: Implications for Research in Academic Learning.

    Science.gov (United States)

    Barringer, Craig; Gholson, Barry

    1979-01-01

    Laboratory research that compared the effects of various types and combinations of feedback on children's conceptual learning was reviewed and evaluated in terms of theories involving reinforcement, motivation, and information-processing interpretations. It was concluded that some important laboratory research findings and implications have been…

  14. Research Status of Track-type Mobile Robots%履带式移动机器人研究现状

    Institute of Scientific and Technical Information of China (English)

    吉洋; 霍光青

    2012-01-01

      介绍了国内外各种履带式机器人的研究现状,对履带式机器人进行了详细描述和总结。指出了履带式机器人研究中存在的问题,提出了履带式机器人未来的发展方向。%  Research status of various types of track-type mobile robots at home and abroad are introduced, detailed description and summary of track-type mobile robots conducted, problems existing in the research of track-type mobile robots listed and development trend of track-type mobile robots presented.

  15. Breeding of maize types with specific traits at the Maize Research Institute, Zemun Polje

    Directory of Open Access Journals (Sweden)

    Pajić Zorica

    2007-01-01

    Full Text Available Maize is primarily grown as an energy crop, but the use of different specific versions, such as high-oil maize, high-lysine maize, waxy maize, white-seeded maize, popping maize and sweet maize, is quite extensive. Speciality maize, due to its traits and genetic control of these traits, requires a particular attention in handling breeding material during the processes of breeding. It is especially related to prevention of uncontrolled pollination. In order to provide successful selection for a certain trait, the following specific procedures in evaluation of the trait are necessary: the estimation of a popping volume and flake quality in popping maize; the determination of sugars and harvest maturity in sweet maize; the determination of oil in selected samples of high-oil maize types, and so forth. Breeding programmes for speciality maize, except high-amylose maize, have been implemented at the Maize Research Institute, Zemun Polje, Belgrade, for the last 45 years. A great number of high-yielding sweet maize hybrids, popping maize, high-oil and high-lysine, flint and white-seeded maize hybrids were developed during this 45-year period. Auspicious selection and breeding for these traits is facilitated by the abundant genetic variability and technical and technological possibilities necessary for successful selection.

  16. Dismantling design for a reference research reactor of the WWR type

    Energy Technology Data Exchange (ETDEWEB)

    Lobach, Yu.N., E-mail: lobach@kinr.kiev.ua [Institute for Nuclear Research, Pr. Nauki, 47, Kiev 03680 (Ukraine); Cross, M.T., E-mail: Martin.Cross@nuvia.co.uk [Nuvia Ltd., Robinson House, Crow Park Way, Westlakes Science and Technology Park, Moor Row, Cumbria CA24 3HY (United Kingdom)

    2014-01-15

    Highlights: • Design features of WWRs relevant to decommissioning have been analysed. • The technical basis for the preparation and implementation of dismantling has been established for a reference WWR. • The applicability of existing proven dismantling technologies has been established. -- Abstract: A decommissioning study has been carried out for a reference research reactor of the WWR type. Many such reactors were constructed more than 50 years ago and most of them are still in operation. Decommissioning has now become an important consideration. This paper summarizes the main decommissioning steps and, on the basis of the reactor design features, technical aspects of the dismantling and removal of the contaminated/activated components have been analysed. The advisability of the removal of large components, such as the reactor vessel and the heat-exchangers, as one piece items has also been demonstrated. Additionally, a work schedule and an estimation of the collective dose for the preparation and implementation of dismantling have been established. The applicability of existing proven dismantling technologies has been identified together with some additional features for the dismantling.

  17. Dairy products and prevention of type 2 diabetes: implications for research and practice.

    Science.gov (United States)

    Kalergis, Maria; Leung Yinko, Sylvie S L; Nedelcu, Roxana

    2013-01-01

    A growing body of scientific evidence has linked dairy intake to a reduced type 2 diabetes (T2D) risk. Using an evidence-based approach, we reviewed the most recent and strongest evidence on the relationship between dairy intake and the risk of T2D. Evidence indicates that dairy intake is significantly associated with a reduced T2D risk, and likely in a dose-response manner. The association between low-fat dairy and T2D risk reduction appears consistent. A beneficial impact is suggested for regular-fat dairy. The role of specific dairy products needs to be clarified. Potential underlying mechanisms include the role of dairy products in obesity and metabolic syndrome, as well as several dairy components, such as calcium, vitamin D, dairy fat, and specifically trans-palmitoleic acid. To conclude, there is strong, consistent, and accumulating evidence that dairy intake reduces the risk of T2D. More research is needed to better understand the role of regular-fat and specific dairy products. Well-designed randomized controlled trials and mechanistic studies are needed to support these findings. Efforts to translate this evidence into clinical practice and public health guidance are needed.

  18. Recent progress in genetic and epigenetic research on type 2 diabetes.

    Science.gov (United States)

    Kwak, Soo Heon; Park, Kyong Soo

    2016-03-11

    Type 2 diabetes (T2DM) is a common complex metabolic disorder that has a strong genetic predisposition. During the past decade, progress in genetic association studies has enabled the identification of at least 75 independent genetic loci for T2DM, thus allowing a better understanding of the genetic architecture of T2DM. International collaborations and large-scale meta-analyses of genome-wide association studies have made these achievements possible. However, whether the identified common variants are causal is largely unknown. In addition, the detailed mechanism of how these genetic variants exert their effect on the pathogenesis of T2DM requires further investigation. Currently, there are ongoing large-scale sequencing studies to identify rare, functional variants for T2DM. Environmental factors also have a crucial role in the development of T2DM. These could modulate gene expression via epigenetic mechanisms, including DNA methylation, histone modification and microRNA regulation. There is evidence that epigenetic changes are important in the development of T2DM. Recent studies have identified several DNA methylation markers of T2DM from peripheral blood and pancreatic islets. In this review, we will briefly summarize the recent progress in the genetic and epigenetic research on T2DM and discuss how environmental factors, genetics and epigenetics can interact in the pathogenesis of T2DM.

  19. Experimental research on electrical propulsion. Note 2: Experimental research on a plasma jet with vortex type stabilization for propulsion

    Science.gov (United States)

    Robotti, A. C.; Oggero, M.

    1985-01-01

    Results of experimental electric propulsion research are presented. A plasma generator, with an arc stabilized by an air vortex is examined. The heat transfer efficiency between arc and fluid environment at a varying current and flow rate is discussed.

  20. What Types of Designs Are We Using in Social Work Research and Evaluation?

    Science.gov (United States)

    Holosko, Michael J.

    2010-01-01

    This article addresses a void in the literature about social work research and evaluation (R&E) designs, in particular related to the quality of its published work. Data were collected by reviewing three empirically oriented journals, "Research on Social Work Practice", "Journal of Social Service Research", and "Social Work Research" over three…

  1. Measurement, growth types and shrinkage of newly formed aerosol particles at an urban research platform

    Science.gov (United States)

    Salma, Imre; Németh, Zoltán; Weidinger, Tamás; Kovács, Boldizsár; Kristóf, Gergely

    2016-06-01

    Budapest platform for Aerosol Research and Training (BpART) was created for advancing long-term on-line atmospheric measurements and intensive aerosol sample collection campaigns in Budapest. A joint study including atmospheric chemistry or physics, meteorology, and fluid dynamics on several-year-long data sets obtained at the platform confirmed that the location represents a well-mixed, average atmospheric environment for the city centre. The air streamlines indicated that the host and neighbouring buildings together with the natural orography play an important role in the near-field dispersion processes. Details and features of the airflow structure were derived, and they can be readily utilised for further interpretations. An experimental method to determine particle diffusion losses in the differential mobility particle sizer (DMPS) system of the BpART facility was proposed. It is based on CPC-CPC (condensation particle counter) and DMPS-CPC comparisons. Growth types of nucleated particles observed in 4 years of measurements were presented and discussed specifically for cities. Arch-shaped size distribution surface plots consisting of a growth phase followed by a shrinkage phase were characterised separately since they supply information on nucleated particles. They were observed in 4.5 % of quantifiable nucleation events. The shrinkage phase took 1 h 34 min in general, and the mean shrinkage rate with standard deviation was -3.8 ± 1.0 nm h-1. The shrinkage of particles was mostly linked to changes in local atmospheric conditions, especially in global radiation and the gas-phase H2SO4 concentration through its proxy, or to atmospheric mixing in few cases. Some indirect results indicate that variations in the formation and growth rates of nucleated particles during their atmospheric transport could be a driving force of shrinkage for particles of very small sizes and on specific occasions.

  2. The First 500 Registrations to the Research Registry(®): Advancing Registration of Under-Registered Study Types.

    Science.gov (United States)

    Agha, Riaz; Fowler, Alexander J; Limb, Christopher; Al Omran, Yasser; Sagoo, Harkiran; Koshy, Kiron; Jafree, Daniyal J; Anwar, Mohammed Omer; McCullogh, Peter; Orgill, Dennis Paul

    2016-01-01

    The Declaration of Helsinki 2013 encourages the registration of all research studies involving human participants. However, emphasis has been placed on prospective clinical trials, and it is estimated that only 10% of observational studies are registered. In response, Research Registry(®) was launched in February 2015; a retrospectively curated registry that is free and easy to use. Research Registry(®) enables prospective or retrospective registration of studies, including those study types that cannot be registered on existing registries. In this study, we describe the first 500 registrations on Research Registry(®). Since the launch of Research Registry(®) in February 2015, data of registrations have been collected, including type of studies registered, country of origin, and data curation activity. Inappropriate registrations, such as duplicates, were identified by the data curation process. These were removed from the database or modified as required. A quality score was assigned for each registration, based on Sir Austin Bradford Hill's criteria on what research studies should convey. Changes in quality scores over time were assessed. A total of 500 studies were registered on Research Registry(®) from February 2015 to October 2015, with a total of 1.7 million patients enrolled. The most common study types were retrospective cohort studies (37.2%), case series (14.8%), and first-in-man case reports (10.4%). Registrations were received from 57 different countries; the most submissions were received from Turkey, followed by China and the United Kingdom. Retrospective data curation identified 80 studies that were initially registered as the incorrect study type, and were subsequently correct. The Kruskal-Wallis test identified a significant improvement in quality scores for registrations from February 2015 to October 2015 (p Research Registry(®) has established itself as a new registry that is free, easy to use, and enables the registration of various

  3. Theoretical research on light propagation in W-type single-mode fiber

    Institute of Scientific and Technical Information of China (English)

    WANG Shu-min; DING Lei; ZHANG Zhi-qin; LU Ke-cheng

    2008-01-01

    We give the characteristic equation of a W-type fiber by solving Maxwell's equations along with boundary conditions at the interfaces. The cutoff condition of the fundamental mode is examined, and a novel W-type fiber working in S-band is designed.

  4. [Three types of bias: distortion of research results and how that can be prevented].

    Science.gov (United States)

    Groenwold, Rolf H H

    2013-01-01

    A systematic distortion of the relationship between a treatment, risk factor or exposure and clinical outcomes is denoted by the term 'bias'. Three types of bias can be distinguished: information bias, selection bias, and confounding. These three types of bias and their potential solutions are discussed using various examples.

  5. The Educational Implications of Type I Diabetes Mellitus: A Review of Research and Recommendations for School Psychological Practice

    Science.gov (United States)

    Kucera, Miranda; Sullivan, Amanda L.

    2011-01-01

    Type I diabetes mellitus (T1DM) is one of the most common chronic illnesses in children and youth, with many affected students requiring individualized services and supports within educational settings. This article systematically reviews the research regarding the implications of this illness for students' cognitive and academic functioning to…

  6. The Educational Implications of Type I Diabetes Mellitus: A Review of Research and Recommendations for School Psychological Practice

    Science.gov (United States)

    Kucera, Miranda; Sullivan, Amanda L.

    2011-01-01

    Type I diabetes mellitus (T1DM) is one of the most common chronic illnesses in children and youth, with many affected students requiring individualized services and supports within educational settings. This article systematically reviews the research regarding the implications of this illness for students' cognitive and academic functioning to…

  7. Discussion on Type-I fuzzy boundary and Research on Boundary Definition of High Order Fuzzy Region

    Directory of Open Access Journals (Sweden)

    Cui Tiejun

    2012-10-01

    Full Text Available The definition of fuzzy boundary is crucial in research of modeling and analysis of fuzzy geographical phenomena. The problem “boundary syndrome” has been a longstanding problem in this domain, and this problem has seriously affected the research and application of fuzzy geographical model. The existing fuzzy boundary models were discussed at first, and then some models based on type-I fuzzy sets were analyzed in detail. This paper pointed out the fuzzy boundary models should have three kinds of meaning: “frontier”, “transition” and “division”. Three types of boundary models of high order fuzzy region were proposed based on interval type-2 fuzzy set, and they embody three kinds of meaning of fuzzy boundary respectively. The models proposed by this paper have a positive effect to high order geographical phenomena modeling and analysis.

  8. [Research on the correlation between Chinese medical syndrome types and objective indices of Wilson's disease].

    Science.gov (United States)

    Wang, Gong-qiang; Ma, Xin-feng; Wang, Wei; Sun, Quan; Zhou, Zhi-hua; Han, Yong-zhu

    2013-11-01

    To explore the correlation between Chinese medical syndrome types of Wilson's disease (WD) and clinical materials as well as physical and chemical indices. Totally 116 WD patients were typed by Chinese medical syndrome. The correlation between Chinese medical syndrome types and clinical materials as well as physical and chemical indices were analyzed using binary stepwise Logistic regression by SPSS 19.0 Software, taking the common Chinese medical syndrome types as the dependent variable and clinical materials as well as physical and chemical indices as the independent variables. Gan-Galibladder dampness-heat syndrome (GGDHS, 35.3%). Gan-stagnation and Pi-deficiency syndrome (GSPDS, 13.8%), Gan-Shen yin deficiency syndrome (GSYDS, 13.8%), and phlegm-dampness retention syndrome (PDRS, 12.1%) were most often seen. GGDHS was positively correlated with grade of K-F ring, total bilirubin (TBIL), alanine transaminase (ALT), laminin (LN) (P types, ceruloplasmin (CP), aspartate aminotransferase (AST), and total protein (TP) (P types were correlated with clinical materials, physical and chemical indices in WD patients, which could provide experimental reference for Chinese medical syndrome typing. GGDHS, GSPDS, GSYDS, and PDRS were most often seen.

  9. Deterministic Analysis of a Beyond Design Basis Accident in a Low Power, Pin-Type Fuel Research Reactor

    Energy Technology Data Exchange (ETDEWEB)

    Nagah Abdou, Hesham Mohammed [INVAP S. E., Bariloche (Argentina)

    2013-07-01

    A Beyond Design Basis Accident has been analyzed for a pool type research reactor with pin-type, Zry4 clad fuel. This is a low power research reactor (maximum power: 100kW) with neutron beam facilities. Two scenarios are considered: a neutron beam rapture that results in a fraction of the core submerged in water and a catastrophic failure that results in a fully uncovered core. The paper discusses the different cooling mechanisms for these two BDBAs and compares results for both scenarios, with predictions of no core damage in any situation. Core damage is defined as CHFR↔1.5 and/or Tclad→T start of breakaway oxidation temperature. In addition, the paper compares calculations with a thermalhydraulic code and an analytical model. This paper allows to analyze the applicability of regular thermalhydraulic codes to BDBA accident scenarios in low power research reactors.

  10. Research on the defect types judgment in wind turbine blades using ultrasonic NDT

    Science.gov (United States)

    Li, Suwei; Shi, Kezhong; Yang, Kun; Xu, Jianzhong

    2015-07-01

    Beacuse of the complex internal structure of wind turbine blades, there are many types of defects. There will be important significance to determine the type of defects to assess the blade residual life and feedback on the design and production process. At present the type of defects found by ultrasonic nondestructive testing (NDT) can't be determined. Physical models of several typical defects are constructed. The sound intensity reflection coefficients of different physical models are calculated seperately, and the calculation method of the sound intensity reflection coefficient of actual defect is presented. Combined the calculated coefficients with the defect information tested, a method of recognize the type of defects is presented. Actual specimen testing is used to verify the effectiveness of the method.

  11. BLOOD CELL ALTERATION MAY AFFECT TYPE 2 DIABETES, PERIODONTITIS, RESEARCHERS SAY

    National Research Council Canada - National Science Library

    Amy E Lund

    2014-01-01

      Modifying certain blood cells may effectively treat or prevent the symptoms of type 2 diabetes and periodontitis simultaneously, according to a report in the August 2014 issue of Journal of Leukocyte Biology...

  12. Research on strong earthquake type division and forecast method for subsequent strong earthquakes

    Institute of Scientific and Technical Information of China (English)

    2000-01-01

    The relationships between energy, amplitude and frequency of earthquake are correlative with the property of the seismic source. And the grade of the correlativity can be used as an index to distinguish the types of strong earthquakes. Primarily the strong earthquake can be divided into three types of main-after earthquakes, double-main earthquakes and swarm of strong earthquake. There are similarity and a certain repeatability at the quantificational indexes of hypocenter property between the same type of strong earthquakes, which supply basis for the forecast of subsequent strong shocks. The reference indexes of after strong shock forecast which are valuable for the applications of the method of type-divided forecast come from the analysis about more than fifty strong shock wide-band (BPZ wave) recording data of CDSN from 1988 to 1997.

  13. Research on the Mechanical Properties of "Z" Type Double-Decker Ball Bearings.

    Science.gov (United States)

    Yu, Chengtao; Xu, Longxiang; Yu, Xudong

    2014-01-01

    The mechanical model of a "Z" type double-decker ball bearing under the action of radial load is established in this paper on the basis of the Hertz contact theory. According to the security contact angle theory, the influences of inner and outer bearings' internal clearances on the bearing's static load carrying capacity, radial deformation, radial stiffness, and load distribution of balls are analyzed. This model is verified in both stationary and rotational loading experiments. Moreover, the simulation results show that the static load carrying capacity of Z type bearing is smaller than that of either inner bearing or outer bearing that is contributed to compose the Z type bearing. The static load carrying capacity of a Z type bearing reduces with the increase of the inner and outer bearings' internal clearance. These simulation results also indicate that the contact angle of the maximum loaded ball in the outer bearing easily exceeds its security contact angle compared with the inner bearing, which, as the main factor, may cause the Z type bearing to overload and to fail. In this sense, the investigated Z type bearings are unfit to apply to situations with heavy load, high speed, or high precision.

  14. Exploring the Types of SMEs Which Could use Blogs as a Marketing Tool: a Proposed Future Research Agenda

    Directory of Open Access Journals (Sweden)

    Adeline Phaik Harn Chua

    2009-08-01

    Full Text Available Blogs appear to be gaining momentum as a marketing tool which can be used by organisations for such strategies and processes as branding, managing reputation, developing customer trust and loyalty, niche marketing, gathering marketing intelligence and promoting their online presence. There has been limited academic research in this area, and most significantly concerning the types of small and medium enterprises (SMEs for which blogs might have potential as a marketing tool. In an attempt to address the knowledge gap, this paper presents a future research agenda (in the form of research questions which can guide the eBusiness research community in conducting much needed studies in this area. This paper is particularly novel in that it aims to demonstrate how the heterogeneity of SMEs and their specific business uses of eBusiness technology such as blogs can form the central plank of a future research agenda. This is important because the existing eBusiness literature tends to treat eBusiness collectively rather than focusing on the specific business uses of different eBusiness technologies, and to treat SMEs as a homogeneous group. The paper concludes with a discussion of how this research agenda can form the basis of studies which use a range of different research methods, and how this "big picture" agenda approach might help the eBusiness research community build theory which better explains SME adoption and use of eBusiness.

  15. Film Coating Process Research and Characterization of TiN Coated Racetrack-type Ceramic Pipe

    CERN Document Server

    Wang, Jie; Zhang, Bo; Wei, Wei; Fan, Le; Pei, Xiangtao; Hong, Yuanzhi; Wang, Yong

    2015-01-01

    TiN film was coated on the internal face of racetrack-type ceramic pipe by three different methods: radio-frequency sputtering, DC sputtering and DC magnetron sputtering. The deposition rates of TiN film under different coating methods were compared. According to the AFM, SEM, XPS test results,these properties were analyzed, such as TiN film roughness and surface morphology. At the same time, the deposition rates were studied under two types' cathode, Ti wires and Ti plate. According to the SEM test results, Ti plate cathode can improve the TiN/Ti film deposition rate obviously.

  16. A Research into the Relationship Between Type a Personality and Emotional Intelligence in Leadership Development

    Directory of Open Access Journals (Sweden)

    Gökhan İncebacak

    2017-05-01

    Full Text Available The aim of this study, which is conducted on male and femaleparticipants and managers from different departments and sectors, is to inves-tigate the relationship between Type A personality traits and emotional intelligence dimensions.In addition, for male and female managers, the emotional intelligence dimensions that are effective on type A personality traits are tried to be determined according to each department. In the results of the analysis conducted on 205 participant managers and the survey used as the data collection tool, different findings were obtained for different departments in male and female managers, and the hypotheses proposed for inter-variable effects and relationships were partially accepted.

  17. A History of Suction-Type Laminar Flow Control with Emphasis on Flight Research

    Science.gov (United States)

    Braslow, Albert L.

    1999-01-01

    Laminar-flow control is an area of aeronautical research that has a long history at NASA's Langley Research Center, Dryden Flight Research Center, their predecessor organizations, and elsewhere. In this monograph, the author, who spent much of his career at Langley working with this research, presents a history of that portion of laminar-flow technology known as active laminar-flow control, which employs suction of a small quantity of air through airplane surfaces. This important technique offers the potential for significant reduction in drag and, thereby, for large increases in range or reductions in fuel usage for aircraft. For transport aircraft, the reductions in fuel consumed as a result of laminar-flow control may equal 30 percent of present consumption. Given such potential, it is obvious that active laminar-flow control with suction is an important technology. In this study, the author covers the early history of the subject and brings the story all the way to the mid-1990s with an emphasis on flight research, much of which has occurred at Dryden. This is an important monograph that not only encapsulates a lot of history in a brief compass but also does so in language that is accessible to non-technical readers. NASA is publishing it in a format that will enable it to reach the wide audience the subject deserves.

  18. Summary of Research on Interactive Safety Analysis Program of Pool Type SFR

    Institute of Scientific and Technical Information of China (English)

    2011-01-01

    The aim of the project was to develop an interactive safety analysis program of pool type sodium cooled fast reactors (SFR), based on a French system code OASIS. The function and physical model of the program should be verified by the application on CEFR design.

  19. Affirmative: In Support of Researching the Myers-Briggs Type Indicator.

    Science.gov (United States)

    Carlson, John G.

    1989-01-01

    Updates 1985 review of Myers-Briggs Type Indicator (MBTI) noting recent criterion-based assessments of the MBTI remain largely unsystematic theoretically but generally positive. Claims more methodologically sophisticated approaches have been developed. Concludes that it seems premature to reject the MBTI owing either to its dichotomous approach to…

  20. Research progress in metallogenic chronology of Mississippi valley-type (MVT) Pb-Zn deposits

    Science.gov (United States)

    Liu, Huiguo

    2017-05-01

    MVT Pb-Zn deposits are one of world’s important Pb-Zn deposits. Their lead and zinc account for approximately 20% of global lead and zinc resources. After constant explorations, researchers have made substantial progress in geological features, geochemical characteristics, ore-forming material sources, and transport and deposition mechanisms for ore-forming fluids, chronology restriction, and geochemical kinetic background for ore genesis of MVT Pb-Zn deposits over the past decades. This paper discusses problems with chronological research by summing up previous outcomes.

  1. Fabrication-Technology Research of New Type Silicon Magnetic-Sensitive Transistor

    Institute of Scientific and Technical Information of China (English)

    Xiaofeng Zhao; Dianzhong Wen

    2006-01-01

    This paper mainly describes a research of fabrication-technology of silicon magnetic-sensitive transistor (SMST) with rectangle-plank-cubic structure fabricated on silicon wafer by MEMS technique. An experiment research on basic characteristic of the silicon magnetic-sensitive transistor was done. Anisotropic etching and reliable technique project were provided and applied in order to fabricate SMST with rectangle-plank-cubic construction. This means that a new kind of fabrication technology for silicon magnetic-sensitive transistor was provided. The result shows that the technique can be not only compatible with IC technology but also integrated easily, and has a wide application field.

  2. A Review of Fatigue Condition in Patients with Type II Diabetes in Isfahan Endocrine and Metabolism Research Center

    Directory of Open Access Journals (Sweden)

    Nasim Vard

    2016-07-01

    Full Text Available Complications of Diabetes such as Fatigue is a serious obstacle hindering the enhancement of health behaviors, including participation in Diabetes self-care programs, and is considered as a challenging problem for nurses and health-care providers in the process of diseases’ treatments and therapies. These complications not only influence the patients’ quality of life, but also, increases the risk of complications. Hence, regarding the importance of the role of fatigue and its subsequent effects on Diabetes’ control as well as the paucity of studies carried out in this field, the current research intended to review fatigue condition in patients with type II Diabetes in Isfahan Endocrine and Metabolism Research Center. The nature of this study is a Quantitative-Descriptive research. For the purpose of the present study, 195 patients with type II Diabetes were selected as the target sample population, based on Non-probability Convenience Sampling Method, from Isfahan Endocrine and Metabolism Research Center. To collect the research data, the researcher used a two-part written questionnaire encompassing Personal Information and Multidimensional Fatigue Symptom Inventory- Short Form (MFSI-SF as the data collection tool. Each of the participants in the present research were briefly advised about the nature and objectives of the research and they were interviewed by the researcher to complete the questionnaire after consent reached with the patients. The collected data was analyzed by SPSS16 statistical analysis software; accordingly the significance level of all the tests was estimated as P˂0.05. The results of the data analysis showed that %85.1 of the patients suffered from fatigue. There was a statistically significant difference between the mean of the severity of fatigue condition between female and male patients in the present study, i.e.23.22 ± 17.49 for women and 13.24 ± 17.73 for men, indexing a significance level of P˂0

  3. Local Sustainable Development and Conservation? : Research into Three Types of Tourism Partnerships in Tanzania.

    NARCIS (Netherlands)

    D.P. de Boer (Diederik)

    2013-01-01

    markdownabstractBusiness community partnerships are vested in private sector development and are the study topic of this research. This study will elaborate on the role of local partnerships to understand to what extent they contribute to a sustainable environment for local socio-economic and

  4. Local Sustainable Development and Conservation? : Research into Three Types of Tourism Partnerships in Tanzania.

    NARCIS (Netherlands)

    D.P. de Boer (Diederik)

    2013-01-01

    markdownabstractBusiness community partnerships are vested in private sector development and are the study topic of this research. This study will elaborate on the role of local partnerships to understand to what extent they contribute to a sustainable environment for local socio-economic and privat

  5. Different Types of Sensation Seeking: A Person-Oriented Approach in Sensation-Seeking Research

    Science.gov (United States)

    Suranyi, Zsuzsanna; Hitchcock, David B.; Hittner, James B.; Vargha, Andras; Urban, Robert

    2013-01-01

    Previous research on sensation seeking (SS) was dominated by a variable-oriented approach indicating that SS level has a linear relation with a host of problem behaviors. Our aim was to provide a person-oriented methodology--a probabilistic clustering--that enables examination of both inter- and intra-individual differences in not only the level,…

  6. Local Sustainable Development and Conservation? : Research into Three Types of Tourism Partnerships in Tanzania.

    NARCIS (Netherlands)

    D.P. de Boer (Diederik)

    2013-01-01

    markdownabstractBusiness community partnerships are vested in private sector development and are the study topic of this research. This study will elaborate on the role of local partnerships to understand to what extent they contribute to a sustainable environment for local socio-economic and privat

  7. Preliminary research on cycloid as a line type of the arch dam

    Institute of Scientific and Technical Information of China (English)

    DU Tingna; YE Rongbo; ZHAO Haifeng

    2012-01-01

    Currently, there are a wide range of line types in the field of arch dam designing and construction, and each of them may have their own strength and weakness disparately. A trade-off between the size, stress, as well as the construction cost and complex- ity of the dam needs to be made in order to arrive at a new solution called the cycloid arch dam. Through redevelopment of VBA us- ing AutoCAD, the arch ring and the center of the arch line have been designed. Also, the stress analysis on parabola and cycloid have been done, which provides a theoretical principle that the cycloid could be regarded as a new line type of the arch dam.

  8. Research on the new type of multi-functional satellite system for space debris detection

    Science.gov (United States)

    Guo, Linghua; Fu, Qiang; Jiang, Huilin; Xu, Xihe

    2017-05-01

    With the rapid development of space exploration and utilization, orbital debris increases dramatically, leading to great threat to human space activities and spacecraft security. In this paper, a new type of multi-functional space debris satellite system (MSDS) was put forward, which shared main optical system, and possessed functions of multidimensional information detection, polarized remote sensing and high rate transmission. The MSDS system can meet the requirements of detection and identification for the small orbital debris which is 1000km faraway, as well as the requirements of the data transmission by 50 Mbps to 2.5 Gbps@200-1000 km. At the same time, by the method of satellite orbital maneuver and attitude adjusting, the orbital debris information that is real-time, complex and refined, allweather can be acquired and transmitted by the new system. Such new type of multifunctional satellite system can provide important and effective technology for international orbital debris detection.

  9. RESEARCH ON THE INELASTIC SEISMIC RESPONSES OF SHEAR-TYPE MULTISTORY BUILDINGS WITH REGULAR ASYMMETRY

    Institute of Scientific and Technical Information of China (English)

    蔡贤辉; 邬瑞锋; 许士斌

    2001-01-01

    The inelastic seismic responses of shear-type multistorey buildings with regular asymmetry were analyzed. The effects of the fundamental lateral period, the fundamental frequency ratio of translational to torsional, the eccentric ratio, earthquake intensity and orthogonal earthquake excitations on inelastic displacement and ductility were studied respectively. Numerical results show that aforementioned factors influence the seismic responses of the buildings. The effect of the orthogonal input of ground motion is likely to be restricted to the moving status of eccentric elements.

  10. Preparation of pyrite-coated sand grains for research on roll-type uranium deposits

    Science.gov (United States)

    Gent, Carol A.

    1977-01-01

    Ordinary quartz sand grains can be coated with pyrite for use in laboratory experiments on the genetic geochemistry of roll-type uranium deposits. The sand is first added to a ferric chloride solution. The slow addition of sodium hydroxide to the mixture gives the sand grains an iron oxide coating. This coating is then converted to pyrite by reaction with hydrogen sulfide, thus yielding a product suitable for experimental use.

  11. Recent progress in genetic and epigenetic research on type 2 diabetes

    OpenAIRE

    Kwak, Soo Heon; Park, Kyong Soo

    2016-01-01

    Type 2 diabetes (T2DM) is a common complex metabolic disorder that has a strong genetic predisposition. During the past decade, progress in genetic association studies has enabled the identification of at least 75 independent genetic loci for T2DM, thus allowing a better understanding of the genetic architecture of T2DM. International collaborations and large-scale meta-analyses of genome-wide association studies have made these achievements possible. However, whether the identified common va...

  12. Preliminary research on syndrome types of Chinese medicine in children with primary nephrotic syndrome.

    Science.gov (United States)

    Sun, Wen; Yu, Jian; Zeng, Gu-Lan; Zhang, Bing-Feng

    2017-08-17

    To provide an objective reference for the syndrome types of Chinese medicine (CM) associated with pediatric primary nephrotic syndrome (PNS). A cross-sectional study was performed. Data on clinical symptoms, CM syndrome types, biochemical indices, and medications used were collected from 98 children with PNS. Then, the correlation between CM syndromes and biochemical indices, as well as medications used, was analyzed. The four most common symptoms in children with PNS were brown urine, red tongue, excessive sweating, and swelling of the face and limbs. The syndromes of qi deficiency of Fei (Lung) and Shen (Kidney) (FSQD) and yin deficiency of Gan (Liver) and Shen (GSYD) were the most common main CM syndrome types. FSQD syndrome score correlated significantly with the total cholesterol level, urine protein/creatinine ratio, and urine IgG and albumin levels (Ptypes were FSQD and GSYD syndromes. FSQD syndrome may be caused by some factors related to lipid levels, protein loss, and the use of immunosuppressive agents. The use of maintenance glucocorticoids may cause GSYD syndrome.

  13. Research on the Development of Baseball Pitching Machine Controlling Pitch Type using Neural Network

    Science.gov (United States)

    Sakai, Shinobu; Oda, Juhachi; Yonemura, Shigeru; Kawata, Kengo; Horikawa, Saburo; Yamamoto, Hiroyuki

    The most common commercial pitching machines for baseball are the "arm" type and the "two rollers" type. These machines tend to have certain limitations. In particular, it is very difficult to simultaneously change both ball speed and direction. In addition, some types of pitches, such as the curveball or screwball, are not easily achieved. In this study, we will explain the hardware and software design of a new "intelligent" pitching machine which can pitch repeatedly with selectable speed, direction and ball rotation. The machine has three rollers and the motion of each is independently controlled by a hierarchical neural network. If the ball speed, direction and rotation are given as input data to this network, signals for controlling the three rollers are produced as output data. The results of a throw experiment with the machine that we developed are shown, which has the ability to pitch assorted breaking balls with a wide range of speeds, from 19.4 to 44.4 m/s. The machine has a speed error of less than about 3%, and a distance error of about 0.15m (twice the length of a ball's diameter).

  14. Heat Transfer Calculation on Plate-Type Fuel Assembly of High Flux Research Reactor

    Directory of Open Access Journals (Sweden)

    Daxin Gong

    2015-01-01

    Full Text Available Heat transfer characteristics of fuel assemblies for a high flux research reactor with a neutron trap are numerically investigated in this study. Single-phase turbulence flow is calculated by a commercial code, FLUENT, where the computational objective covers standard and control fuel assemblies. The simulation is carried out with an inlet coolant velocity varying from 4.5 m/s to 7.5 m/s in hot assemblies. The results indicate that the cladding temperature is always lower than the saturation temperature in the calculated ranges. The temperature rise in the control fuel assembly is smaller than that of the standard fuel assembly. Additionally, the assembly with a hot spot is specially studied, and the safety of the research reactor is also approved.

  15. Research on Design of Plate-type Electromagnetic Coupler in Underwater Inductive Power Transmission

    Directory of Open Access Journals (Sweden)

    Qu Li-yan

    2015-01-01

    Full Text Available Magnetic coupler has a good application in the field of underwater sensor. Magnetic coupler at work, interference by underwater complex situation, stability and efficiency of charging device of the gap is larger fluctuations. The traditional electromagnetic coupling is charging for the stability of the clearance to demand higher. Charging for underwater, as a result of the existence of ocean currents, electromagnetic coupling clearance may not remain very stable. When there is deviation gap, a larger electromagnetic coupling performance deviation. On this particular problem, it puts forward the design method of a new type of plate type electromagnetic coupling. First of all, the leakage inductance of the finite element method to calculate system and excitation inductance, establish electromagnetic coupler with compensation capacitor equivalent circuit, and the primary circuit and secondary circuit was designed. On the basis, the voltage gain and efficiency of the system are carrying on the theoretical derivation and calculation. The simulation experimental results show that the magnetic coupler has a stable voltage gain and charging efficiency, when the partial core within 10 mm, voltage gain remains steady at 5.8%, efficiency remain at around 90%.

  16. Research on Practicability and Feasibility for a New-Type Tuned Mass Damper System-TMD

    Institute of Scientific and Technical Information of China (English)

    2001-01-01

    Based on the principle of tuned mass damper (TMD), the method of using laminated rubber bearing (LRB) to connect TMD with structure is discussed in this paper. This is a new type of TMD systemsuspended structure. To test the function of quake-reduction and the possibility of application, this paper explores the suspended top floor through shaking table test. In the model test, an electro-hydraulic shaking table was used. The main structure model was a four-story steel frame structure. The block to combat the structural quake was a concrete block. LRB was used to connect the block to the main structure. In order to analyze the efficiency of TMD, the fundamental frequencies of the main structure and block of TMD were measured separately first. Then, the frequencies of the main structure with the block and without the block were compared respectively under sine and imitative quake waves. The test shows that this new-typeTMD system is effective in combating the structural quake often reducing the acceleration of the top floor by more than 25 %. Because of the easy availability of the method, it is endowed with practical feasibility.

  17. Research on a new type of fiber Bragg grating based corrosion sensor

    Science.gov (United States)

    Li, Peng; Song, Shide; Wang, Xiaona; Zhou, Weijie; Zhang, Zuocai

    2015-08-01

    Investigations of the corrosion of rebars in concrete structures are widely studied because of the serious damage to concrete caused by rebar corrosion. The rebar corrosion products in reinforced concrete take up 2~6 times the volume of the rebar. Based on this principle, a new type of fiber Bragg grating (FBG) corrosion sensor is proposed in this paper, which consists of two sensors, an FBG corrosion measurement sensor to measure the expansion strain caused by rebar corrosion, and a temperature compensation sensor to eliminate the cross-sensitivity of FBG corrosion sensor. The corrosion rate is derived by the wavelength shift of FBG corrosion sensor, so rebar corrosion can be monitored and assessed by the FBG wavelength shift. A customized rebar with epoxy fixing groove is designed to install a corrosion sensor on its surface and an embedded temperature compensation sensor. The corrosion sensor is embedded in cement mortar and subsequently casted in concrete. The performance of the corrosion sensor is studied in an accelerated electrochemical corrosion test. Experimental results show that the new type of corrosion sensor has advantage of relatively large measurement range of corrosion rate. The corrosion sensor is suitable to monitor slightly and moderately corroded rebars.

  18. Research on menu-typed man-machine interaction system of digital TIG welding machine

    Institute of Scientific and Technical Information of China (English)

    何建萍; 张春波; 孙广; 吴毅雄; 焦馥杰

    2004-01-01

    A digital man-machine interaction system controlled by communications between two processors of TMS320F240 and AT98C2051 was researched in the paper. The system is easy to set and modify welding process parameters by keyboards, and display information of welding site by LCD (Liquid Crystal Display). As one part of multi-task system about TIG welding machine, the coordination of man-machine interaction system with other tasks is the main point to the stability and reliability of its operation. Experiments result indicates that the system is stable, operation-flexible, high precision, and anti-interfering.

  19. Type 2 diabetes: genetic data sharing to advance complex disease research.

    Science.gov (United States)

    Flannick, Jason; Florez, Jose C

    2016-09-01

    As with other complex diseases, unbiased association studies followed by physiological and experimental characterization have for years formed a paradigm for identifying genes or processes of relevance to type 2 diabetes mellitus (T2D). Recent large-scale common and rare variant genome-wide association studies (GWAS) suggest that substantially larger association studies are needed to identify most T2D loci in the population. To hasten clinical translation of genetic discoveries, new paradigms are also required to aid specialized investigation of nascent hypotheses. We argue for an integrated T2D knowledgebase, designed for a worldwide community to access aggregated large-scale genetic data sets, as one paradigm to catalyse convergence of these efforts.

  20. Research on mutual influence of Cherenkov-type probes within the ISTTOK tokamak chamber

    Energy Technology Data Exchange (ETDEWEB)

    Jakubowski, L., E-mail: lech.jakubowski@ncbj.gov.pl [National Centre for Nuclear Research (NCBJ), 05-400 Otwock (Poland); Plyusnin, V.V. [Association Euratom/IST, Instituto de Plasmas e Fusão Nuclear, Instituto Superior Técnico, Av. Rovisco Pais, 1049-001 Lisboa (Portugal); Malinowski, K.; Sadowski, M.J.; Zebrowski, J.; Rabinski, M. [National Centre for Nuclear Research (NCBJ), 05-400 Otwock (Poland); Fernandes, H.; Silva, C.; Figueiredo, H. [Association Euratom/IST, Instituto de Plasmas e Fusão Nuclear, Instituto Superior Técnico, Av. Rovisco Pais, 1049-001 Lisboa (Portugal); Jakubowski, M.J. [National Centre for Nuclear Research (NCBJ), 05-400 Otwock (Poland)

    2014-12-11

    The paper describes an influence of a Cherenkov-type probe, which is used for measurements of fast electron streams inside the ISTTOK chamber, on other probes and behaviour of a plasma ring. The reported study shows that such a probe situated near the plasma column has a strong influence on signals from another Cherenkov probe, and can cause a considerable reduction of electron-induced signals. This effect does not depend on positions of the probes in relation to the limiter. Measurements of hard X-ray (HXR) emission show that the deeply immersed Cherenkov probe can also influence on the limiter . Under specific experimental conditions such a Cherenkov probe can play the role of a new limiter and change the plasma configuration.

  1. Research on the Wave-Induced Ship Motions in Front of Different Types of Wharf

    Science.gov (United States)

    Li, Yan Bao; Jiang, Xue Lian

    One important function of the port is to protect ship or some other facilities from wave attack so as to stably handle cargoes. In current design codes, there are mainly two expressions of the tranquility standard of harbor basin: one is the acceptable wave height in front of wharf; the other is the tolerable amplitude of ship motion. However, ship motions are affected by some more factors simultaneously, such as wave frequency, wave height, incident wave direction, ship properties and wharf type. This paper presents some computed results of the wave-induced ship motions on the basis of a port case in China. First, the Simple Green Function method is employed to solve and compare the 2-dimension hydrodynamic coefficients in front of open or bulkhead wharf. The results show a great difference between them. Then, this paper computes and discusses the ship motions in front of open wharf at different wave frequencies and incident wave directions.

  2. New national Biobank of The Danish Center for Strategic Research on Type 2 Diabetes (DD2)

    DEFF Research Database (Denmark)

    Christensen, Henry; Nielsen, Jens Steen; Sørensen, Karina Meden

    2012-01-01

    received at the biobank, samples are frozen without further treatment. From each patient, 24 cryostorage tubes are stored. Each tube is labeled with a barcode that links the data to other information available in a clinical databank registry. When patients are enrolled in DD2, a questionnaire is filled out...... samples from 8-10 patients arrive per day. We have established the first national biobank in Denmark where blood, DNA, and plasma and urine samples from patients with newly diagnosed T2D are systematically collected and stored. This biobank enables sophisticated analysis of genetic variation and response......-term outcome of patients with newly diagnosed type 2 diabetes (T2D). The DD2 project includes establishment of a biobank with samples from 50,000 patients with newly diagnosed T2D. This paper describes how blood and urine samples from 10,000 patients per year are collected, handled, and stored. The biobank...

  3. Prevalence and types of mobbing behavior: A research on banking employees

    Directory of Open Access Journals (Sweden)

    Sibel Gök

    2011-01-01

    Full Text Available This article presents a case study of the most frequently observed types of mobbing behavior, the level of exposure to mobbing behavior according to the characteristics of participants and the prevalence of bullying among a group of banking employees in Istanbul, Turkey. 384 participants were assessed by a questionnaire including 18 item mobbing behaviors. The results has shown that exposure to mobbing in this study group is widespread. 32% of the participants were determined to be victims of mobbing (during the entire working life. 16% of participants reported that they had been bullied at their workplaces within the last year. Significant difference was found between the tenure of the participants and their exposure to mobbing. Also, the supervisor was reported as a perpetrator by 69.9% of mobbing victims in the sample.

  4. Thermal-hydraulic Fortran program for steady-state calculations of plate-type fuel research reactors

    Directory of Open Access Journals (Sweden)

    Khedr Ahmed

    2008-01-01

    Full Text Available The safety assessment of research and power reactors is a continuous process covering their lifespan and requiring verified and validated codes. Power reactor codes all over the world are well established and qualified against real measuring data and qualified experimental facilities. These codes are usually sophisticated, require special skills and consume a lot of running time. On the other hand, most research reactor codes still require much more data for validation and qualification. It is, therefore, of benefit to any regulatory body to develop its own codes for the review and assessment of research reactors. The present paper introduces a simple, one-dimensional Fortran program called THDSN for steady-state thermal-hydraulic calculations of plate-type fuel research reactors. Besides calculating the fuel and coolant temperature distributions and pressure gradients in an average and hot channel, the program calculates the safety limits and margins against the critical phenomena encountered in research reactors, such as the onset of nucleate boiling, critical heat flux and flow instability. Well known thermal-hydraulic correlations for calculating the safety parameters and several formulas for the heat transfer coefficient have been used. The THDSN program was verified by comparing its results for 2 and 10 MW benchmark reactors with those published in IAEA publications and a good agreement was found. Also, the results of the program are compared with those published for other programs, such as the PARET and TERMIC.

  5. New N-Type Polymers for Organic Photovoltaics: Cooperative Research and Development Final Report, CRADA Number CRD-06-177

    Energy Technology Data Exchange (ETDEWEB)

    Olson, D.

    2014-08-01

    This CRADA will develop improved thin film organic solar cells using a new n-type semiconducting polymer. High efficiency photovoltaics (PVs) based on inorganic semiconductors have good efficiencies (up to 30%) but are extremely expensive to manufacture. Organic PV technology has the potential to overcome this problem through the use of high-throughput production methods like reel-to-reel printing on flexible substrates. Unfortunately, today's best organic PVs have only a few percent efficiency, a number that is insufficient for virtually all commercial applications. The limited choice of stable n-type (acceptor) organic semiconductor materials is one of the key factors that prevent the further improvement of organic PVs. TDA Research, Inc. (TDA) previously developed a new class of electron-deficient (n-type) conjugated polymers for use in organic light emitting diodes (OLEDs). During this project TDA in collaboration with the National Renewable Energy Laboratory (NREL) will incorporate these electron-deficient polymers into organic photovoltaics and investigate their performance. TDA Research, Inc. (TDA) is developing new materials and polymers to improve the performance of organic solar cells. Materials being developed at TDA include spin coated transparent conductors, charge injection layers, fullerene derivatives, electron-deficient polymers, and three-phase (fullerene/polythiophene/dye) active layer inks.

  6. Research progress on the brewing techniques of new-type rice wine.

    Science.gov (United States)

    Jiao, Aiquan; Xu, Xueming; Jin, Zhengyu

    2017-01-15

    As a traditional alcoholic beverage, Chinese rice wine (CRW) with high nutritional value and unique flavor has been popular in China for thousands of years. Although traditional production methods had been used without change for centuries, numerous technological innovations in the last decades have greatly impacted on the CRW industry. However, reviews related to the technology research progress in this field are relatively few. This article aimed at providing a brief summary of the recent developments in the new brewing technologies for making CRW. Based on the comparison between the conventional methods and the innovative technologies of CRW brewing, three principal aspects were summarized and sorted, including the innovation of raw material pretreatment, the optimization of fermentation and the reform of sterilization technology. Furthermore, by comparing the advantages and disadvantages of these methods, various issues are addressed related to the prospect of the CRW industry.

  7. Benefits in cash or in kind? A community consultation on types of benefits in health research on the Kenyan Coast.

    Science.gov (United States)

    Njue, Maureen; Molyneux, Sassy; Kombe, Francis; Mwalukore, Salim; Kamuya, Dorcas; Marsh, Vicki

    2015-01-01

    Providing benefits and payments to participants in health research, either in cash or in kind, is a common but ethically controversial practice. While much literature has concentrated on appropriate levels of benefits or payments, this paper focuses on less well explored ethical issues around the nature of study benefits, drawing on views of community members living close to an international health research centre in Kenya. The consultation, including 90 residents purposively chosen to reflect diversity, used a two-stage deliberative process. Five half-day workshops were each followed by between two and four small group discussions, within a two week period (total 16 groups). During workshops and small groups, facilitators used participatory methods to share information, and promote reflection and debate on ethical issues around types of benefits, including cash, goods, medical and community benefits. Data from workshop and field notes, and voice recordings of small group discussions, were managed using Nvivo 10 and analysed using a Framework Analysis approach. The methods generated in-depth discussion with high levels of engagement. Particularly for the most-poor, under-compensation of time in research carries risks of serious harm. Cash payments may best support compensation of costs experienced; while highly valued, goods and medical benefits may be more appropriate as an 'appreciation' or incentive for participation. Community benefits were seen as important in supporting but not replacing individual-level benefits, and in building trust in researcher-community relations. Cash payments were seen to have higher risks of undue inducement, commercialising relationships and generating family conflicts than other benefits, particularly where payments are high. Researchers should consider and account for burdens families may experience when children are involved in research. Careful context-specific research planning and skilled and consistent communication about

  8. Benefits in cash or in kind? A community consultation on types of benefits in health research on the Kenyan Coast.

    Directory of Open Access Journals (Sweden)

    Maureen Njue

    Full Text Available Providing benefits and payments to participants in health research, either in cash or in kind, is a common but ethically controversial practice. While much literature has concentrated on appropriate levels of benefits or payments, this paper focuses on less well explored ethical issues around the nature of study benefits, drawing on views of community members living close to an international health research centre in Kenya.The consultation, including 90 residents purposively chosen to reflect diversity, used a two-stage deliberative process. Five half-day workshops were each followed by between two and four small group discussions, within a two week period (total 16 groups. During workshops and small groups, facilitators used participatory methods to share information, and promote reflection and debate on ethical issues around types of benefits, including cash, goods, medical and community benefits. Data from workshop and field notes, and voice recordings of small group discussions, were managed using Nvivo 10 and analysed using a Framework Analysis approach.The methods generated in-depth discussion with high levels of engagement. Particularly for the most-poor, under-compensation of time in research carries risks of serious harm. Cash payments may best support compensation of costs experienced; while highly valued, goods and medical benefits may be more appropriate as an 'appreciation' or incentive for participation. Community benefits were seen as important in supporting but not replacing individual-level benefits, and in building trust in researcher-community relations. Cash payments were seen to have higher risks of undue inducement, commercialising relationships and generating family conflicts than other benefits, particularly where payments are high. Researchers should consider and account for burdens families may experience when children are involved in research. Careful context-specific research planning and skilled and consistent

  9. A High Operability Supervisory Digital System for TRIGA-Type Research Reactors

    Energy Technology Data Exchange (ETDEWEB)

    Aronica, O.; Bove, R.; Cappelli, M.; Falconi, L.; Palomba, M.; Santoro, E.; Sepielli, M. [ENEA, UTFISST, Casaccia Research Center, Via Anguillarese, 301 Rome (Italy); Memmi, F. [University of Rome ' Roma Tre' , Department of Electrical Engineering, Via della Vasca Navale, 84 Rome (Italy)

    2011-07-01

    In this work, we propose an outline of a monitoring system to supervise variables coming from a fission nuclear reactor of TRIGA type (1-MW TRIGA reactor RC-1). The system can interface the control room instrumentation and can display the characteristic parameters (e.g. nuclear power, temperatures, flow rates, radiological parameters) in an intuitive, user-friendly way for plant operators. This aim is achieved using the Labview development environment. A front panel of a virtual instrument allows for a direct measure and a check that would not be possible by only reading the output data coming from the instruments of the control room, because of their standards and strict safety regulations. The acquisition system, for signals coming from the reactor, can process data and generate a detailed representation of the results. Statistics resulting from data analysis will be interpreted to optimize reactor management parameters. This system also includes a simulation tool to predict specific performances and investigate critical phenomena, or to optimize overall plant performances. In particular, it allows to have a feedback control and to perform predictive statistical surveys of all main process parameters. (author)

  10. CLINICAL RESEARCH ON MOXIBUSTION TREATMENT OF DIARREHEA TYPE IRRITABLE BOWEL SYNDROME

    Institute of Scientific and Technical Information of China (English)

    倪莹莹; 陆建芹

    2001-01-01

    Objective: To observe the therapeutic effect of moxibustion in treatment of diarrhea type irritable bowel syndrome (IBS). Methods: 56 cases of IBS were divided into treatment group (n=30) and control group (n=26). Patients of the former group were treated with moxibustion of Guanyuan (CV 4) and Zusanli (ST 36) in combination with Xiajuxu (ST 39) for lowering abdominal pain and with Shangjuxu (ST 37) for left lower abdominal pain; whilethose of the later group were treated with oral administration of Nifedipinum (10 mg, 3 times a day) and Smecta (1 bag, 3 times daily). After 15 days' treatment, the therapeutic effect was evaluated. Results: After treatment, the effective rates for abdominal pain, abdominal distension, abnormal frequency, abnormal stool, dyspepsia in treatment group were 100.00%, 94.74%, 96.67%, 100.00% and 95.00% respectively, with a total improving rate of 79.30% ; and those in control group 95.65%, 82.35%, 92.31%, 96.15% and 75.00% separately, with the total improving rate being 63.98%. There were significant differences between two groups in the effective rate of dyspepsia and the total improving rate of symptoms (P<0.05,0.01 ). Conclusion: Moxibustion treatment is effective in treatment of IBS and superior to that of Western medicines

  11. Research on a New Type of Energy Feedback Cascade Multilevel Inverter System

    Directory of Open Access Journals (Sweden)

    Yu Jianhua

    2013-01-01

    Full Text Available Traditional cascade multilevel inverter can only transmit one-direction of energy. This paper proposes a new cascade multilevel inverter topology and control strategy based on part units to realize the energy feedback. By using PWM converter to replace uncontrollable converter in part units of the traditional inverter, and combining the inverter with H-bridge inverter, the two-direction running of the cascade inverter is realized. A double closed loop control strategy is used to obtain fine control characteristic of input current. The carrier phase-shifted SPWM technology is adopted in the cascade inverter to reduce harmonious wave of output voltage and current, meanwhile, a new type of bypass control method is proposed to collect all the feedback energy and restore it into the energy feedback units. According to the simulation of a three-phase and five-unit cascaded inverter with three energy feedback units, the results demonstrate that the proposed inverter can be input near sinusoidal current , and realize two-way flow of energy automatically with simplified phase shifting transformer structure, and show its feasibility and effectiveness.

  12. The Effects of Industry Type, Company Size and Performance on Chinese Companies’ IC Disclosure: A Research Note

    Directory of Open Access Journals (Sweden)

    Yi An

    2011-09-01

    Full Text Available This paper examines the effects of industry type, firm size and corporate performance on intellectual capital (IC disclosure among Chinese (mainland companies. It was found that industry type did not have a significant influence on IC reporting practices of Chinese firms; the larger firms generally reported more IC information than the relatively smaller firms; and there was a positive relationship between corporate performance and IC disclosure. This paper contributes to fairly limited literature regarding the associations between the level of IC disclosure and a variety of relevant impact factors, in particular in the Chinese mainland context. In addition, the findings of this research provide some references for policy-makers while developing an IC reporting framework applicable to the Chinese environment.

  13. Research of association between the primary progressive type of pterygium and the tear film

    Directory of Open Access Journals (Sweden)

    Jin-Kui Cheng

    2014-09-01

    Full Text Available AIM:To research the association between primary progressive pterygium and tear film. METHODS: Totally 60 cases of primary progressive pterygium from September 2012 to June 2013 in our hospital were enrolled. The pterygium eye was for observation group and the contralateral eye as the control group. The differences of eye symptoms, tear film break-up time(BUT, SchirmerⅠ test(SⅠt, corneal fluorescein staining(FL, tear ferning test(TFTand the conjunctival impression cytology(CICwere compared between two groups.RESULTS: The eyes in observation group had higher symptoms score, FL score, grades of conjunctival squamous metaplasia, percentage of abnormal tear ferning, but had lower BUT and density of goblet cell, the differences had statistically significance(PP>0.05. CONCLUSION: Primary progressive pterygium can cause a decrease in tear film stability, which in turn lead to some dry eye symptoms such as dry feeling and burning sensation, and its mechanism may be caused by multi-factors, such as density change of goblet cell and the tear fluid dynamics.

  14. Research on the interfacial behaviors of plate-type dispersion nuclear fuel elements

    Science.gov (United States)

    Wang, Qiming; Yan, Xiaoqing; Ding, Shurong; Huo, Yongzhong

    2010-04-01

    The three-dimensional constitutive relations are constructed, respectively, for the fuel particles, the metal matrix and the cladding of dispersion nuclear fuel elements, allowing for the effects of large deformation and thermal-elastoplasticity. According to the constitutive relations, the method of modeling their irradiation behaviors in ABAQUS is developed and validated. Numerical simulations of the interfacial performances between the fuel meat and the cladding are implemented with the developed finite element models for different micro-structures of the fuel meat. The research results indicate that: (1) the interfacial tensile stresses and shear stresses for some cases will increase with burnup, but the relative stresses will decrease with burnup for some micro-structures; (2) at the lower burnups, the interfacial stresses increase with the particle sizes and the particle volume fractions; however, it is not the case at the higher burnups; (3) the particle distribution characteristics distinctly affect the interfacial stresses, and the face-centered cubic case has the best interfacial performance of the three considered cases.

  15. T1DBase: update 2011, organization and presentation of large-scale data sets for type 1 diabetes research.

    Science.gov (United States)

    Burren, Oliver S; Adlem, Ellen C; Achuthan, Premanand; Christensen, Mikkel; Coulson, Richard M R; Todd, John A

    2011-01-01

    T1DBase (http://www.t1dbase.org) is web platform, which supports the type 1 diabetes (T1D) community. It integrates genetic, genomic and expression data relevant to T1D research across mouse, rat and human and presents this to the user as a set of web pages and tools. This update describes the incorporation of new data sets, tools and curation efforts as well as a new website design to simplify site use. New data sets include curated summary data from four genome-wide association studies relevant to T1D, HaemAtlas-a data set and tool to query gene expression levels in haematopoietic cells and a manually curated table of human T1D susceptibility loci, incorporating genetic overlap with other related diseases. These developments will continue to support T1D research and allow easy access to large and complex T1D relevant data sets.

  16. RESEARCH OF THE TYPES OF POSTURES OF THE WOMAN FIGURE FOR THE PURPOSE OF DEVELOPING HIGH QUALITY GARMENTS

    Directory of Open Access Journals (Sweden)

    ALCAZ Olga

    2015-05-01

    Full Text Available The high interchangeability of produced garments and the increased requirements towards the quality of production is conditioned by the growing individualization of orders, this is why it is important to perform systematically anthropometric researches of the modern female population for the purpose of revealing the peculiarities of constitution of the figures of this consumer group. During the researches, the existing classifications and data on the postures and types of body constitution of women were studied. The point of departure was the healthy human vertebral column and the position of human body in normal posture. The aspects of possible deviations from the normal body posture were studied. Taking into consideration the fact that various age groups were examined in the paper, various age-related modifications of the vertebral column and, thus, of the human posture were studied. To attain the established goal, anthropometric researches were performed on women of various age groups. The studied women were taken photos; using the photos, the figure contours were obtained, and the types of body constitutions and postures were studied according to the methods described in the special literature. The obtained data were analyzed and presented in graphic form for a more precise visualization of the results and for a more exact interpretation of those results. The result of the performed researches was the classification of postural defects, revealed in the frontal and sagittal planes, taking into consideration the eventual peculiarities of the individual figure of any age. This classification is meant to facilitate the work of the designers at the stage of projecting or when making corrections in the design of garments.

  17. Trends in the types and quality of childhood immunisations research output from Africa 1970-2010: mapping the evidence base.

    Science.gov (United States)

    Machingaidze, Shingai; Hussey, Gregory D; Wiysonge, Charles S

    2014-02-04

    Over the past four decades, extraordinary progress has been made in establishing and improving childhood immunization programmes around Africa. In order to ensure effective and sustainable positive growth of these childhood immunisations programmes, the development, adaptation and implementation of all interventions (programme activities, new vaccines, new strategies and policies) should be informed by the best available local evidence. An assessment of the peer-reviewed literature on childhood immunization research published in English from 1970 to 2010 was conducted in PubMed and Africa-Wide databases. All study types were eligible for inclusion. A standard form was used to extract information from all studies identified as relevant and entered into a Microsoft Access database for analysis. Our initial search yielded 5436 articles from the two databases, from which 848 full text articles were identified as relevant. Among studies classified as clinical research (417), 40% were clinical trials, 24% were burden of disease/epidemiology and 36% were other clinical studies. Among studies classified as operational research (431), 77% related to programme management, 18% were policy related and 5% were related to vaccine financing. Studies were conducted in 48 African countries with six countries (South Africa, The Gambia, Nigeria, Senegal, Guinea-Bissau and Kenya) accounting for 56% of the total research output. Studies were published in 152 different journals with impact factors ranging from 0.192 to 53.29; with a median impact factor of 3.572. A similar proportion of clinical versus operational research output was found. However, an uneven distribution across Africa was observed with only six countries accounting for over half of the research output. The research conducted was of moderate to high quality, with 62% being published in journals with 2010 impact factors greater than two. Urgent attention should be given to the development of research capacity in low

  18. Three types of ambiguity in coding empathic interactions in primary care visits: implications for research and practice.

    Science.gov (United States)

    Stone, Ashley L; Tai-Seale, Ming; Stults, Cheryl D; Luiz, Jamie M; Frankel, Richard M

    2012-10-01

    To describe three methodological challenges experienced in studying patients' expressions of emotion in a sample of periodic health exams, and the research and practice implications of these challenges. Qualitative analysis of empathic cues in audio-taped and transcribed periodic health examinations of adult patients (n=322) in an integrated delivery system. The empathic and potential empathic opportunities methodology was used. Identifying emotional cues that constitute "empathic opportunities" is a complex task. Three types of ambiguity made this task particularly challenging: 1) presentations of emotional cues can be "fuzzy" and varied; 2) expressions of illness can be emotionally laden in the absence of explicit "emotion words"; and 3) empathic opportunities vary in length and intensity. Interactional ambiguities pose a challenge to researchers attempting to document emotional cues with a binary coding scheme that indicates only whether an empathic opportunity is present or absent. Additional efforts to refine the methodological approach for studying empathy in medical interactions are needed. The challenges discussed likely represent the same types of situations physicians find themselves in when talking with patients. Highlighting these ambiguities may aid physicians in better recognizing and meeting the emotional needs of their patients. Copyright © 2012 Elsevier Ireland Ltd. All rights reserved.

  19. Notes on shark and ray types at the South China Sea Fisheries Research Institute (SCSFRI) in Guangzhou, China.

    Science.gov (United States)

    White, William T; Last, Peter R

    2013-01-01

    Most of the shark and ray type material at the South China Sea Fisheries Research Institute (SCSFRI) in Guangzhou, China was examined during a museum visit by the senior author in 2009. The status of the shark and ray species described from the South China Sea in the 1980s and deposited in this collection is discussed. Squalus acutirostris is considered a junior synonym of Squalus mitsukurii from the western North Pacific. Centrophorus ferrugineus is considered a junior synonym of Centrophorus squamosus. Centroscymnus macrops is confirmed as a junior synonym of Centroscymnus coelolepis. Scymnodon niger is confirmed as a junior synonym of Zameus squamulosus. Isistius labialis is considered a synonym of Isistius brasiliensis. Halaelurus immaculatus is confirmed as a valid species of the genus Bythaelurus. Urolophus marmoratus is considered a junior synonym of the widespread Plesiobatis daviesi. Springeria nanhaiensis is a questionable synonym of Sinobatis borneensis, following previous researchers. Springeria stenosoma is considered as questionably valid but with further investigation into generic placement required. The validity of species with SCSFRI type specimens not examined in this study are also briefly discussed.

  20. 胃癌分子分型研究进展%Research progress of molecular type of gastric cancer

    Institute of Scientific and Technical Information of China (English)

    刘静文; 刘红利; 张涛

    2014-01-01

    胃癌是发病率及致死率较高的一种恶性肿瘤。胃癌的病理分型是以组织形态结构和细胞生物学特性为基础,不同类型的胃癌,其形态结构和生物学行为各异,流行病学和分子机制亦不同,以致现有的胃癌病理分型系统众多。以往常用的病理分型包括Borrmann分型、Lauren分型和WHO分型,已有的这些胃癌分型对临床指导意义有限。最新的研究对295例胃癌进行综合性分子分析,这是癌症基因组图谱(TCGA)计划工作的一部分,基于对所得数据的分析整合,提出了一种新的胃癌分子分型,将其分为四个亚型:EBV感染型;微卫星不稳定(MSI)型;基因组稳定(GS)型;染色体不稳定(CIN)型。该研究于2014年7月23日在《nature》在线发表,新发现的胃癌分子分型有助于胃癌个体化治疗靶向药物的筛选。本文将对胃癌的分子分型研究展开综述。%Gastric cancer is a kind of malignant tumor which has higher incidence and mortality rate. Its pathological type is based on the morphological structure of tissue and cell biological characteristics. Not only morphological structure and biological characteristics but epidemiology and molecular mechanism are also different for each type, which makes so many typing systems come out. Usual pathological types include Borrmann type, Lauren type and WHO type. All these types have limited significance for clinic. The latest research analyzed 295 primary gastric carcinomas at comprehensive molecular stage, which is also a part of TCGA (The Cancer Genome Atlas) project. Ultimately, they put forward a new typing system which divided gastric cancer into four types including tumor positive for Epstein-Barr virus (EBV), microsatellite instable (MSI) tumors, genomically stable (GS) tumors and tumor with chromosomal instability (CIN). The study was published in the‘nature’ online in July 23, 2014, which contributed to targeted

  1. [The National Research Program 1A: a community-oriented intervention study. Methodological considerations on various types of studies].

    Science.gov (United States)

    Gutzwiller, F

    1980-11-01

    Intervention tricals can principally be classified into community or clinically oriented designs. The clinical approach of the randomized controlled trial (RCT) implies the individual randomization of a volunteer population into a study and a control group. In community-oriented trials, however, the study and control group are not composed of individuals, but rather of total population groups (e.g. communities, factories). The paper gives first an overview over the historial development of epidemiological methods as the basis for both study types. Shortcomings and advantages both of RCT's and of community trials are discussed, using the examples of the "diet-heart" hypothesis and of the National Research Program 1A design, respectively. The two study types uses as primary endpoints for the analysis changes in risk factor distribution, morbidity and/or mortality. A recent alternative is presented, too: advances in angiography allow direct measurements of changes in vessels with atherosclerotic disease. The different study types available complement one another in trying to understand the mechanisms involved in disease of multifactorial origin.

  2. Correlation Between Insight and Capacity to Consent to Research in Subjects With Bipolar Disorder Type I and Schizophrenia.

    Science.gov (United States)

    López-Jaramillo, Carlos; Tobler, Chantal Aristizábal; Gómez, Constanza Ovalle; Triana, Jaime Escobar

    2016-01-01

    Schizophrenia and bipolar disorder type I (BD-I) can affect patient autonomy and capacity to consent to participate in research. Other variables associated with the autonomy of patients must be explored in order to improve the quality of the currently available tools. To evaluate the relationship between insight and the capacity to consent to participate in research in patients with BD-I and schizophrenia. A cross-sectional and longitudinal study was conducted with 120 subjects (40 subjects with schizophrenia, 40 with BD-I, and 40 healthy controls). The tools used were the Scale Assessment Insight-Expanded (SAI-E) and the MacArthur Competence Assessment Tool-Treatment (MacCAT-CR), which was first adapted culturally, and its validity and reliability assessed. The results obtained on each scale were compared and the association between them were evaluated. There is a direct correlation between the capacity to consent to research, measured using the MacCAT-CR tool, and the degree of insight, measured using the SAI-E scale, with an effect size of 1.3 for BD-I and 2.03 for schizophrenia. The results suggest that there is a correlation between the degree of insight and the capacity to consent to research in subjects with schizophrenia and BD-I. Insight should therefore be included as a relevant variable to assess the capacity to consent, and future studies should include it when researching on or designing new tools which aim at a greater respect of patient autonomy. Copyright © 2016 Asociación Colombiana de Psiquiatría. Publicado por Elsevier España. All rights reserved.

  3. Development of in-vessel type control rod drive mechanism for a innovative small reactor (Contract research)

    Energy Technology Data Exchange (ETDEWEB)

    Yoritsune, Tsutomu; Ishida, Toshihisa [Japan Atomic Energy Research Inst., Tokai, Ibaraki (Japan). Tokai Research Establishment

    2003-03-01

    Although the control rod drive mechanism of an existing large scale light water reactor is generally installed outside the reactor vessel, an in-vessel type control rod drive mechanism (INV-CRDM) is installed inside the reactor vessel. The INV-CRDM contributes to compactness and simplicity of the reactor system, and it can eliminate the possibility of a rod ejection accident. Therefore, INV-CRDM is an important technology adopted in an innovative small reactor. Japan Atomic Energy Research Institute (JAERI) has developed this type of CRDM driven by an electric motor, which can work under high temperature and high pressure water for the advanced marine reactor. On the basis of this research result, a driving motor coil and a bearing were developed to be used under the high temperature steam, severe condition for an innovative small reactor. About the driving motor, we manufactured the driving motor available for high temperature steam and carried out performance test under room temperature atmosphere to confirm the electric characteristic and coolability of the driving coil. With these test results and the past test results under high temperature water, we analyzed and evaluated the electric performance and coolability of the driving coil under high temperature steam. Concerning bearing, we manufactured the test pieces using some candidate material for material characteristic test and carried out the rolling wear test under high temperature steam to select the material. Consequently, we confirmed that performance of the driving coil for the advanced type driving motor, is enough to be used under high temperature steam. And, we evaluated the performance of the bearing and selected the material of the bearing, which can be used under high temperature steam. From these results, we have obtained the prospect that the INV-CRDM can be used for an innovative small reactor under steam atmosphere could be developed. (author)

  4. Development of in-vessel type control rod drive mechanism for a innovative small reactor (Contract research)

    Energy Technology Data Exchange (ETDEWEB)

    Yoritsune, Tsutomu; Ishida, Toshihisa [Japan Atomic Energy Research Inst., Tokai, Ibaraki (Japan). Tokai Research Establishment

    2003-03-01

    Although the control rod drive mechanism of an existing large scale light water reactor is generally installed outside the reactor vessel, an in-vessel type control rod drive mechanism (INV-CRDM) is installed inside the reactor vessel. The INV-CRDM contributes to compactness and simplicity of the reactor system, and it can eliminate the possibility of a rod ejection accident. Therefore, INV-CRDM is an important technology adopted in an innovative small reactor. Japan Atomic Energy Research Institute (JAERI) has developed this type of CRDM driven by an electric motor, which can work under high temperature and high pressure water for the advanced marine reactor. On the basis of this research result, a driving motor coil and a bearing were developed to be used under the high temperature steam, severe condition for an innovative small reactor. About the driving motor, we manufactured the driving motor available for high temperature steam and carried out performance test under room temperature atmosphere to confirm the electric characteristic and coolability of the driving coil. With these test results and the past test results under high temperature water, we analyzed and evaluated the electric performance and coolability of the driving coil under high temperature steam. Concerning bearing, we manufactured the test pieces using some candidate material for material characteristic test and carried out the rolling wear test under high temperature steam to select the material. Consequently, we confirmed that performance of the driving coil for the advanced type driving motor, is enough to be used under high temperature steam. And, we evaluated the performance of the bearing and selected the material of the bearing, which can be used under high temperature steam. From these results, we have obtained the prospect that the INV-CRDM can be used for an innovative small reactor under steam atmosphere could be developed. (author)

  5. Types of treatment collaboration between conventional and alternative practitioners – results from a research project at a Danish MS hospital

    Directory of Open Access Journals (Sweden)

    Lasse Skovgaard

    2010-12-01

    Full Text Available Introduction: More than 50% of the People with Multiple Sclerosis (PwMS in Denmark use alternative treatment. Most of them combine alternative and conventional treatment, but PwMS often find that there is no dialogue, coordination or synergy between the parallel courses of treatment offered. For this reason the Danish Multiple Sclerosis Society conducted a research project to develop and examine different models for collaboration between conventional and alternative treatment providers. Materials and methods: Empirical material consist of individual interviews with practitioners, a group interview with practitioners, a group interview with professional staff at the Danish MS hospital that provided the organisational framework for the project, interviews with patients as well as written responses from participating treatment providers in connection with practitioner-researcher seminars held. Results: Collaboration between researchers and the treatment team resulted in the development examination of several models which describe the strengths and weaknesses of various types of collaboration. The models also show that the various types of collaboration place different requirements on the degree of 1 mutual acknowledgement and understanding among practitioners, 2 flexibility and resources in the organizational framework, and 3 patients' activities and own efforts, respectively.    Perspectives: The relationship between integration and pluralism can contribute to a fruitful discussion in regards to the value of treatment collaboration. In addition to the many positive perspectives the characterise integration of different treatment modalities the project points to the importance of not overlooking the opportunities, values and potential inherent in a pluralistic ideal in the form of patients' own active efforts and the dynamism that can arise when the patient becomes a co-informant, co-coordinator and/or co-integrator.

  6. Types of treatment collaboration between conventional and alternative practitioners – results from a research project at a Danish MS hospital

    Directory of Open Access Journals (Sweden)

    Lasse Skovgaard

    2010-12-01

    Full Text Available Introduction: More than 50% of the People with Multiple Sclerosis (PwMS in Denmark use alternative treatment. Most of them combine alternative and conventional treatment, but PwMS often find that there is no dialogue, coordination or synergy between the parallel courses of treatment offered. For this reason the Danish Multiple Sclerosis Society conducted a research project to develop and examine different models for collaboration between conventional and alternative treatment providers. Materials and methods: Empirical material consist of individual interviews with practitioners, a group interview with practitioners, a group interview with professional staff at the Danish MS hospital that provided the organisational framework for the project, interviews with patients as well as written responses from participating treatment providers in connection with practitioner-researcher seminars held. Results: Collaboration between researchers and the treatment team resulted in the development examination of several models which describe the strengths and weaknesses of various types of collaboration. The models also show that the various types of collaboration place different requirements on the degree of 1 mutual acknowledgement and understanding among practitioners, 2 flexibility and resources in the organizational framework, and 3 patients' activities and own efforts, respectively.    Perspectives: The relationship between integration and pluralism can contribute to a fruitful discussion in regards to the value of treatment collaboration. In addition to the many positive perspectives the characterise integration of different treatment modalities the project points to the importance of not overlooking the opportunities, values and potential inherent in a pluralistic ideal in the form of patients' own active efforts and the dynamism that can arise when the patient becomes a co-informant, co-coordinator and/or co-integrator. 

  7. Fieldwork Test Research of the Impact on Building Physical Environment on Six Types of Atrium Space in Cold Climates

    Institute of Scientific and Technical Information of China (English)

    YeHao Song; JunJie Li; Ning Zhu; JiaLiang Wang; ZhengHao Lin

    2014-01-01

    Since the research on verification to passive design strategies in sustainable building is at the initial stage, and its test method and verification conclusion are not scientific enough to validate, this paper proposes the necessity of building physical environmental monitoring to quantitative optimization of passive strategies efficiency from the perspective of architecture design and building environment. Adopting comparative research method, this research chooses six types of atrium space in cold climate in China as a prototype, focusing on building physical environmental performance difference in and between atrium and building main space. Spatial parameters of the atrium space will be divided into four factors:spatial geometry, interfacial properties, internal and external related categories. With subdividing these four factors into sub-factors, this paper makes cross-comparison among the sub-factors to clarify passive strategies effectiveness in atrium. Data comparison analysis shows that Winter atrium passive strategy in cold regions from traditional view is not obvious in practical application, and test data need to be stratified refined in atrium design in case of optimizing passive strategy from building prototype perspective.

  8. Research

    African Journals Online (AJOL)

    ebutamanya

    2016-07-13

    Jul 13, 2016 ... Data analyses were performed using Epi-Info 3.5.4 software. ... outcomes calls for clinicians, to consider additional management options, such as antibiotic .... type of delivery, type of anaesthesia, gender of neonates, neonatal.

  9. Reporting and handling of missing data in predictive research for prevalent undiagnosed type 2 diabetes mellitus: a systematic review.

    Science.gov (United States)

    Masconi, Katya L; Matsha, Tandi E; Echouffo-Tcheugui, Justin B; Erasmus, Rajiv T; Kengne, Andre P

    2015-01-01

    Missing values are common in health research and omitting participants with missing data often leads to loss of statistical power, biased estimates and, consequently, inaccurate inferences. We critically reviewed the challenges posed by missing data in medical research and approaches to address them. To achieve this more efficiently, these issues were analyzed and illustrated through a systematic review on the reporting of missing data and imputation methods (prediction of missing values through relationships within and between variables) undertaken in risk prediction studies of undiagnosed diabetes. Prevalent diabetes risk models were selected based on a recent comprehensive systematic review, supplemented by an updated search of English-language studies published between 1997 and 2014. Reporting of missing data has been limited in studies of prevalent diabetes prediction. Of the 48 articles identified, 62.5% (n = 30) did not report any information on missing data or handling techniques. In 21 (43.8%) studies, researchers opted out of imputation, completing case-wise deletion of participants missing any predictor values. Although imputation methods are encouraged to handle missing data and ensure the accuracy of inferences, this has seldom been the case in studies of diabetes risk prediction. Hence, we elaborated on the various types and patterns of missing data, the limitations of case-wise deletion and state-of the-art methods of imputations and their challenges. This review highlights the inexperience or disregard of investigators of the effect of missing data in risk prediction research. Formal guidelines may enhance the reporting and appropriate handling of missing data in scientific journals.

  10. Neutron activation analysis at the Livermore pool-type reactor for the environmental research program. [Identification of trace element contaminants

    Energy Technology Data Exchange (ETDEWEB)

    Ragaini, R.C.; Heft, R.E.; Garvis, D.

    1976-07-02

    Instrumental neutron activation analysis is a technique of trace analysis using measurements of radioactivity induced in the sample by exposure to a source of neutrons. The induced activity is measured by the emitted gamma radiation. Each gamma emitter can then be identified by the energy of the photopeaks produced as the nuclide decays and by the half-life of the neutron-induced activity. A complex computer program GAMANAL has been used to accomplish the major tasks of nuclide identification and quantification. The nuclide data output from GAMANAL is processed by a second computer code NADAC, which develops elemental abundance data from disintegration rates observed. The methods are those employed at the Livermore Pool-Type Reactor in support of the environmental research trace element analysis program. Among the procedures described and discussed are sample preparation, irradiation, analysis, and application of the technique.

  11. Establishment of Motion Model for Wave Capture Buoy and Research on Hydrodynamic Performance of Floating-Type Wave Energy Converter

    Directory of Open Access Journals (Sweden)

    Gao Hongtao

    2015-09-01

    Full Text Available Floating-type wave energy converter has the advantages of high wave energy conversion efficiency, strong shock resistance ability in rough sea and stable output power. So it is regarded as a promising energy utilization facility. The research on hydrodynamic performance of wave capture buoys is the precondition and key to the wave energy device design and optimization. A simplified motion model of the buoys in the waves is established. Based on linear wave theory, the equations of motion of buoys are derived according to Newton’s second law. The factors of wave and buoys structural parameters on wave energy absorption efficiency are discussed in the China’s Bohai Sea with short wave period and small wave height. The results show that the main factor which affects the dynamic responses of wave capture buoys is the proximity of the natural frequency of buoys to the wave period. And the incoming wave power takes a backseat role to it at constant wave height. The buoys structural parameters such as length, radius and immersed depth, influence the wave energy absorption efficiency, which play significant factors in device design. The effectiveness of this model is validated by the sea tests with small-sized wave energy devices. The establishment methods of motion model and analysis results are expected to be helpful for designing and manufacturing of floating-type wave energy converter.

  12. The Danish Centre for Strategic Research in Type 2 Diabetes (DD2) study: implementation of a nationwide patient enrollment system.

    Science.gov (United States)

    Nielsen, Jens Steen; Thomsen, Reimar W; Steffensen, Charlotte; Christiansen, Jens S

    2012-01-01

    This paper aims to describe the patient enrollment system and implementation strategy for the new nationwide Danish Centre for Strategic Research in Type 2 Diabetes (DD2) project. The paper will also describe the design, current content, and pilot testing of the DD2 registration form. The challenge of the DD2 project was to construct a registration system functioning in the entire Danish health care system, where new type 2 diabetes patients are initially met, and with the capacity to enroll 200 newly diagnosed diabetes patients per week nationwide. This requires a fast and simple registration that is part of everyday clinical practice in hospital outpatient clinics and general practitioner (GP) clinics. The enrollment system is thus built on a tested, rational design where patients need only one visit and only specific limited data about physical activity, anthropometric measures, and family history of diabetes are collected during a brief patient interview. Later, supplemental data will be extracted by computerized linkage with existing databases. The feasibility of this strategy was verified in a pilot study. For maximum flexibility, three different ways to fill in the DD2 registration form were provided and an interactive webpage was constructed. The DD2 project also involves collection of blood and urine samples from each diabetes patient, to be stored in a biobank. Clinicians may obtain the samples themselves or refer patients to the nearest clinical biochemical department. GPs have the additional option of referring patients to the nearest hospital outpatient diabetes clinic to obtain interview data, clinical data, and samples. At present, the enrollment system is in use at 17 hospital outpatient diabetes clinics and 45 GP clinics nationwide, together enrolling 40 new type 2 diabetes patients per week in the DD2 project. A total of 990 patients have now been enrolled and the DD2 is ready to expand nationwide.

  13. Research

    African Journals Online (AJOL)

    A possible strategy to influence students' understanding and perception ... researcher in higher education teaching and learning facilitated the data- ..... B. Qualitative content analysis in nursing research: Concepts, procedures and measures.

  14. The upgrade and conversion of the ET-RR-1 research reactor using plate type fuel elements

    Energy Technology Data Exchange (ETDEWEB)

    Ashoub, N. [Reactor Physics Dept., Nuclear Research Center, Atomic Energy Authority, Cairo (Egypt); Saleh, H.G. [Faculty of Girls for Arts and Education, Ain-Shams Univ., Cairo (Egypt)

    2001-11-01

    The ET-RR-1 research reactor has been operated at 2 MW since 1961 using EK-10 fuel elements with 10% enriched uranium. The reactor has been used for nuclear applied research and isotope production. In order to upgrade the reactor power to a reasonable limit facing up-to-date uses, core conversion by a new type of fuel element available is necessary. Two fuel elements in plate type are suggested in this study to be used in the ET-RR-1 reactor core rather than the utilized ones. The first element has a dimension of 8 x 8 x 50 cm and consists of 19.7% enriched uranium, which is typical for that utilized in the ET-RR-2 reactor, but with a different length. The other element is proposed with a dimension of 7 x 7 x 50 cm and has the same uranium enrichment. To accomplish safety requirements for these fuel elements, thermal-hydraulic evaluation has been carried out using the PARET code. To reach a core conversion of the ET-RR-1 reactor with the above two types of fuel elements, neutronic calculations have been performed using WIMSD4, DIXY2 and EREBUS codes. Some important nuclear parameters needed in the physical design of the reactor were calculated and included in this study. (orig.) [German] Der ET-RR-1 Forschungsreaktor wird seit 1961 unter Verwendung von EK-10 Brennelementen mit einer Leistung von 2 MW betrieben. Der Reaktor wird in der angewandten Forschung und zur Isotopenherstellung eingesetzt. Um die Reaktorleistung im Hinblick auf eine zeitgemaesse Nutzung der Anlage in einem vernuenftigen Mass zu erhoehen, ist eine Umwandlung des Kerns durch Verwendung neuartiger Brennelemente noetig. In der vorliegenden Untersuchung wird vorgeschlagen, anstelle der z. Z. verwendeten Elemente zwei neue, plattenfoermige Brennelemente zu verwenden. Das erste Element hat eine Groesse von 8 x 8 x 50 cm und besteht aus 19,7% angereichertem Uran, was den im ET-RR-2 Reaktor verwendeten Elementen entspricht, allerdings mit einer anderen Groesse. Das zweite Element hat die gleiche

  15. A qualitative study of the relationship of personality type with career management and career choice preference in a group of bioscience postgraduate students and postdoctoral researchers

    OpenAIRE

    Blackford, Sarah

    2010-01-01

    This study reports on the career management and career choice preferences of a sample of bioscience postgraduate students and postdoctoral researchers according to their personality type as determined using the Myers Briggs Type Indicator (MBTI). Correlations can be found but other decision-making processes come into play and are more influential regarding career choices

  16. High risk of cardiovascular disease in patients with type 1 diabetes mellitus in the UK, a cohort study using the General Practice Research Database

    NARCIS (Netherlands)

    Soedamah-Muthu, S.S.; Fuller, J.H.; Mulnier, H.E.; Raleigh, V.S.; Lawrenson, R.A.; Colhoun, H.M.

    2006-01-01

    OBJECTIVE—To estimate the absolute and relative risk of cardiovascular disease (CVD) in patients with type 1 diabetes in the U.K. RESEARCH DESIGN AND METHODS—Subjects with type 1 diabetes (n = 7,479) and five age- and sex-matched subjects without diabetes (n = 38,116) and free of CVD at baseline

  17. A qualitative study of the relationship of personality type with career management and career choice preference in a group of bioscience postgraduate students and postdoctoral researchers

    OpenAIRE

    Blackford, Sarah

    2010-01-01

    This study reports on the career management and career choice preferences of a sample of bioscience postgraduate students and postdoctoral researchers according to their personality type as determined using the Myers Briggs Type Indicator (MBTI). Correlations can be found but other decision-making processes come into play and are more influential regarding career choices

  18. The Danish Centre for Strategic Research in Type 2 Diabetes (DD2 study: implementation of a nationwide patient enrollment system

    Directory of Open Access Journals (Sweden)

    Nielsen JS

    2012-09-01

    Full Text Available Jens Steen Nielsen,1 Reimar W Thomsen,2 Charlotte Steffensen,2 Jens S Christiansen31Department of Endocrinology M, Odense University Hospital, Odense, 2Department of Clinical Epidemiology, 3Department of Endocrinology, Aarhus University Hospital, Aarhus, DenmarkAbstract: This paper aims to describe the patient enrollment system and implementation strategy for the new nationwide Danish Centre for Strategic Research in Type 2 Diabetes (DD2 project. The paper will also describe the design, current content, and pilot testing of the DD2 registration form. The challenge of the DD2 project was to construct a registration system functioning in the entire Danish health care system, where new type 2 diabetes patients are initially met, and with the capacity to enroll 200 newly diagnosed diabetes patients per week nationwide. This requires a fast and simple registration that is part of everyday clinical practice in hospital outpatient clinics and general practitioner (GP clinics. The enrollment system is thus built on a tested, rational design where patients need only one visit and only specific limited data about physical activity, anthropometric measures, and family history of diabetes are collected during a brief patient interview. Later, supplemental data will be extracted by computerized linkage with existing databases. The feasibility of this strategy was verified in a pilot study. For maximum flexibility, three different ways to fill in the DD2 registration form were provided and an interactive webpage was constructed. The DD2 project also involves collection of blood and urine samples from each diabetes patient, to be stored in a biobank. Clinicians may obtain the samples themselves or refer patients to the nearest clinical biochemical department. GPs have the additional option of referring patients to the nearest hospital outpatient diabetes clinic to obtain interview data, clinical data, and samples. At present, the enrollment system is in use at

  19. 体育智库的类型研究%Research on the Type of Sport Think Tank

    Institute of Scientific and Technical Information of China (English)

    代方梅; 王靖; 余君

    2016-01-01

    This paper uses methods of literature consultation, comparative analysis to analyze the types of sport think tank, present the nature and characteristics of all kinds of sport think tanks , and discusses the measures for the coordinated development of all kinds of sport think tanks. According to the actual situation of the existing sports science consultation system, sport think tank is divided into the subordinate sports decision room, sports science research institute, sports academic groups, industry associations and research forum, colleges and universities and related research center (institute), sports media organizations and other of the official integrated scientific research institution. On the basis of the comparative analysis of the distinctive features , living environment and development trend of all kinds of sport think tanks , proposed the establishment of the decision-making consultation system, broaden the investment channels of sport think tank, innovation personnel training and mobility mechanism, strengthen the path of differentiation and other measures, so as to achieve the common development of all kinds of sport think tank.%采用文献资料、比较分析等方法研究体育智库的类型,分析各类体育智库的性质及特点,探讨各类体育智库共同协调发展的措施。根据现有体育科学咨询系统的实际情况,体育智库主要分为官方综合型科研机构下属的体育决策室、体育科学研究所、体育学术团体、行业协会和研究论坛、高等院校及其相关研究中心(所)、体育传播机构等类型。根据各类体育智库特征、生存环境以及发展态势,提出促进各类体育智库协同发展的建立决策咨询制度、拓宽体育智库投资渠道、创新人才培养与流动机制、强化差异化发展路径等措施。

  20. Research

    African Journals Online (AJOL)

    A sequential mixed-methods research design was chosen. This research ... development of the questionnaire used in the second phase of the survey. Quantitative data ... Microsoft Office Excel 2010 spreadsheet, descriptive data analysis was applied .... undergraduate curriculum, and implementation and evaluation thereof,.

  1. Research

    African Journals Online (AJOL)

    ebutamanya

    2015-03-02

    Mar 2, 2015 ... Shared and mutually beneficial resources within international research ... organizations[1-9]. ... facilitate research career paths, but few career models exist in Africa ..... international and local resources to clinical studies locally. The ability of ... investigators were seen as an important asset for the transfer of.

  2. Research

    African Journals Online (AJOL)

    abp

    2013-08-08

    Aug 8, 2013 ... Details of distribution and types of calcification as well as demographics of the ... peripheral blood smear does not preclude the diagnosis of filariasis. This was ... means of a bite from a mosquito (that has previously bitten an.

  3. Research

    African Journals Online (AJOL)

    tend to be cognitively, emotionally and behaviourally involved in their ... gender, age, type of school (urban v. rural), attendance of peer-mentoring ..... The relationship between emotional intelligence, test anxiety, stress, academic success and ...

  4. Research

    African Journals Online (AJOL)

    abp

    2015-06-15

    Jun 15, 2015 ... The most accessed app types were disease management apps (88% ... These were mainly disease management apps, procedure .... Morrison J, Shrestha NR, Hayes B, Zimmerman M. Mobile .... Human resources for health.

  5. Research

    African Journals Online (AJOL)

    raoul

    2011-10-19

    Oct 19, 2011 ... to the recognition of the need to train veterinary epidemiologists in a .... had been trained in several types of short courses in the countries ... for example the Global Disease Detection program in Kenya from 2006 and PEPFAR.

  6. Metabonomics research of diabetic nephropathy and type 2 diabetes mellitus based on UPLC-oaTOF-MS system

    Energy Technology Data Exchange (ETDEWEB)

    Zhang Jie, E-mail: jiezhang@dicp.ac.cn [Key Laboratory for Chemical Biology of Fujian Province, College of Chemistry and Chemical Engineering, Xiamen University, 361005 Xiamen (China); Yan Lijuan [XiaMen Entry-Exit Inspection and Quarantine Bureau, 361012 Xiamen (China); Chen Wengui [First Hospital of Xiamen, 361003 Xiamen (China); Lin Lin [Key Laboratory for Chemical Biology of Fujian Province, College of Chemistry and Chemical Engineering, Xiamen University, 361005 Xiamen (China); Song Xiuyu [First Hospital of Xiamen, 361003 Xiamen (China); Yan Xiaomei [Key Laboratory for Chemical Biology of Fujian Province, College of Chemistry and Chemical Engineering, Xiamen University, 361005 Xiamen (China); Hang Wei, E-mail: weihang@xmu.edu.cn [Key Laboratory for Chemical Biology of Fujian Province, College of Chemistry and Chemical Engineering, Xiamen University, 361005 Xiamen (China); Huang Benli [Key Laboratory for Chemical Biology of Fujian Province, College of Chemistry and Chemical Engineering, Xiamen University, 361005 Xiamen (China)

    2009-09-14

    Ultra performance liquid chromatography (UPLC) coupled with orthogonal acceleration time-of-flight (oaTOF) mass spectrometry has showed great potential in diabetes research. In this paper, a UPLC-oaTOF-MS system was employed to distinguish the global serum profiles of 8 diabetic nephropathy (DN) patients, 33 type 2 diabetes mellitus (T2DM) patients and 25 healthy volunteers, and tried to find potential biomarkers. The UPLC system produced information-rich chromatograms with typical measured peak widths of 4 s, generating peak capacities of 225 in 15 min. Furthermore, principal component analysis (PCA) was used for group differentiation and marker selection. As shown in the scores plot, the distinct clustering between the patients and controls was observed, and DN and T2DM patients were also separated into two individual groups. Several compounds were tentatively identified based on accurate mass, isotopic pattern and MS/MS information. In addition, significant changes in the serum level of leucine, dihydrosphingosine and phytoshpingosine were noted, indicating the perturbations of amino acid metabolism and phospholipid metabolism in diabetic diseases, which having implications in clinical diagnosis and treatment.

  7. Irradiation strategies for the production of Co{sup 60} in a MTR-type research reactor

    Energy Technology Data Exchange (ETDEWEB)

    Jatuff, Fabian E. [Investigacion Aplicada S.E. (INVAP), San Carlos de Bariloche (Argentina)

    1996-07-01

    There were analyzed some possible irradiation strategies for cobalt devices in a 10-MW MTR-type research, with radioisotope production criteria of 50000 Ci/year - provided by the extraction of pellets with 200 Ci/g as average specific activity. The present activity calculations rely on a series of six assumptions concerning the cycle length, the spatial treatment of pins with cobalt pellets and the bundle of pins, the calculation of absorption rates for each region and energy group the determination of appropriate macroscopic cross sections, the determination of appropriate fluxes, and the consideration of cobalt burnup in alternate cycles of T{sub 1} irradiation days followed by T{sub 2} decay days. It is shown the only irradiation strategy of two years of permanence of the cobalt device in different locations in the core and reflector for the reference bundle design - and some others strategies of three years of permanence - satisfying the design criteria. In addition, there studied alternative designs for the cobalt bundle, and the reactivity worth of cobalt for the safety analysis. Alternatives to the reference cobalt bundle seem to improve activities only in few percents. Typical uncertainties are estimated in a 10%. (author)

  8. A simple interpretation of the growth of scientific/technological research impact leading to hype-type evolution curves

    CERN Document Server

    Campani, Marco

    2014-01-01

    The empirical and theoretical justification of Gartner hype curves is a very relevant open question in the field of Technological Life Cycle analysis. The scope of the present paper is to introduce a simple model describing the growth of scientific/technological research impact, in the specific case where science is the main source of a new idea driving a technological development, leading to hype-type evolution curves. The main idea of the model is that, in a first stage, the growth of the scientific interest of a new specific field (as can be measured by publication numbers) basically follows the classical logistic growth curve. At a second stage, starting at a later trigger time, the technological development based on that scientific idea (as can be measured by patent deposits) can be described as the integral (in a mathematical sense) of the first curve, since technology is based on the overall accumulated scientific knowledge. The model is tested through a bibliometric analysis of the publication and pat...

  9. Soil erosion and degradation in Mediterranean Type Ecosystems. The Soil Erosion and Degradation Research Group (SEDER) approach and findings

    Science.gov (United States)

    Cerdà, Artemi; Keesstra, Saskia; Pulido, Manuel; Jordán, Antonio; Novara, Agata; Giménez-Morera, Antonio; Borja, Manuel Esteban Lucas; Francisco Martínez-Murillo, Juan; Rodrigo-Comino, Jesús; Pereira, Paulo; Nadal-Romero, Estela; Taguas, Tani; Úbeda, Xavier; Brevik, Eric C.; Tarolli, Paolo; Bagarello, Vicenzo; Parras Alcantara, Luis; Muñoz-Rojas, Miriam; Oliva, Marc; di Prima, Simone

    2017-04-01

    .1016/j.earscirev.2014.07.005 Bodí, M. B., Martin, D. A., Balfour, V. N., Santín, C., Doerr, S. H., Pereira, P., . . . Mataix-Solera, J. (2014). Wildland fire ash: Production, composition and eco-hydro-geomorphic effects. Earth-Science Reviews, 130, 103-127. doi:10.1016/j.earscirev.2013.12.007 Cerdà, A., González-Pelayo, O., Giménez-Morera, A., Jordán, A., Pereira, P., Novara, A., . . . Ritsema, C. J. (2016). Use of barley straw residues to avoid high erosion and runoff rates on persimmon plantations in eastern spain under low frequency-high magnitude simulated rainfall events. Soil Research, 54(2), 154-165. doi:10.1071/SR15092 Cerdà, A., Lavee, H., Romero-Díaz, A., Hooke, J., & Montanarella, L. (2010). Preface: Soil erosion and degradation in mediterranean type ecosystems. Land Degradation and Development, 21(2), 71-74. doi:10.1002/ldr.968 Dlapa, P., Bodí, M. B., Mataix-Solera, J., Cerdà, A., & Doerr, S. H. (2015). Organic matter and wettability characteristics of wildfire ash from mediterranean conifer forests. Catena, 135, 369-376. doi:10.1016/j.catena.2014.06.018 Keesstra, S., Pereira, P., Novara, A., Brevik, E. C., Azorin-Molina, C., Parras-Alcántara, L., . . . Cerdà, A. (2016). Effects of soil management techniques on soil water erosion in apricot orchards. Science of the Total Environment, 551-552, 357-366. doi:10.1016/j.scitotenv.2016.01.182 Lucas-Borja, M. E., Hedo, J., Cerdá, A., Candel-Pérez, D., & Viñegla, B. (2016). Unravelling the importance of forest age stand and forest structure driving microbiological soil properties, enzymatic activities and soil nutrients content in mediterranean spanish black pine(pinus nigra ar. ssp. salzmannii) forest. Science of the Total Environment, 562, 145-154. doi:10.1016/j.scitotenv.2016.03.160 Novara, A., Cerdà, A., Carmelo, D., Giuseppe, L. P., Antonino, S., & Luciano, G. (2015). Effectiveness of carbon isotopic signature for estimating soil erosion and deposition rates in sicilian vineyards. Soil and

  10. Research

    African Journals Online (AJOL)

    raoul

    2012-02-17

    Feb 17, 2012 ... This is an Open Access article distributed under the terms of the Creative ..... However, this system has great potential to negatively affect access to ... Dr. Samuel Yaw Opoku: Defining the Concept and Research Design; ...

  11. Research

    African Journals Online (AJOL)

    abp

    2016-04-26

    Apr 26, 2016 ... Management of biomedical waste in two medical laboratories in Bangui, Central ... Research .... Central African Republic Ministry of Health and corresponding ethics ..... In CAR, the management of BW remains embryonic. It is.

  12. Research

    African Journals Online (AJOL)

    ebutamanya

    2015-08-28

    Aug 28, 2015 ... Ethiopia, 2Bahir Dar Regional Health Research Laboratory Center, Department ... of Public Health, 4Institute of Medical Microbiology and Epidemiology of Infectious .... active ingredient x 10,000 dilution rate of product): 0.1%.

  13. Research

    African Journals Online (AJOL)

    raoul

    2011-03-11

    Mar 11, 2011 ... ... to General Organization of Teaching Hospitals and Institutes, Egypt, 2Department of .... Ethiopia at Max-Burger Research Institute, Leipzig, Germany ... [22] than Croatia (50%), Australia (53%), Thailand (41%), Italy (32.6%), ...

  14. Research

    African Journals Online (AJOL)

    7, No. 1 AJHPE. Research. A comprehensive approach to curriculum evaluation is deemed ... While evaluators are guided by the experiences of using different methods, ..... provided a follow-up in-depth exploration of the quantitative results.

  15. Research

    African Journals Online (AJOL)

    ... community in the design, conduct and/or evaluation of these activities. ... During Phase I of the mixed-methods research design, data were collected by ... A questionnaire survey was administered to all students registered for ... Data analysis.

  16. Research

    African Journals Online (AJOL)

    ebutamanya

    2016-02-03

    Feb 3, 2016 ... Published in partnership with the African Field Epidemiology Network (AFENET). (www.afenet.net) .... What is known about this topic ... India Co-ordinated Research Project. Ministry .... African Journal of Biotechnology. 2005 ...

  17. Research

    African Journals Online (AJOL)

    raoul

    2011-12-06

    Dec 6, 2011 ... Asia indicate a high incidence of Kikuchi lymphadenitis [6]. However ... It is believed that information derived from this study will be of immense value to the attending physician and also form a baseline data for future research.

  18. Research

    African Journals Online (AJOL)

    judicious use of current best evidence in making decisions about the care of individual ... [5] This highlights that teaching research methodology is inclined ... to evidence-based practice in final-year undergraduate physiotherapy students.

  19. Research

    African Journals Online (AJOL)

    curricula to address health systems changes and challenges .... Likert scale questions were used, along with open-ended qualitative questions. ... Clear communicator: Able to communicate important aspects of theory, research findings clearly ...

  20. researchers

    African Journals Online (AJOL)

    levels who is fluent in only Afrikaans and English. Differences in race .... The lack of knowledge of a particular vernacular often places a researcher firmly as an ..... discourse of African American women', Black women in the academy. Promises.

  1. Research

    African Journals Online (AJOL)

    2014-05-06

    May 6, 2014 ... Methods. The researchers used an exploratory, sequential mixed-method design, ... This design is useful to explore a topic, using qualitative ... interview a Delphi questionnaire was used to gather additional quantitative.

  2. Research

    African Journals Online (AJOL)

    Research. Clinical teaching is a technique used in the education of nurses. It ... learnt in a contextualised learning environment, which should support them in their ..... development of continuing professional development strategies. This study ...

  3. Research

    African Journals Online (AJOL)

    ebutamanya

    2016-03-03

    Mar 3, 2016 ... radiation therapy [9, 10]. The signs of obstructive ... year's undergraduate medical student: socio-demographic including age (in years), sex. .... awareness and enhance further research in this domain. Conclusion. Patients ...

  4. Research

    Science.gov (United States)

    Mathematics Teaching, 1973

    1973-01-01

    Implications for teachers from Piagetian-oriented piagetian-oriented research on problem solving reported in an article by Eleanor Duckworth are presented. Edward de Bono's Children Solve Problems,'' a collection of examples, is also discussed. (MS)

  5. Research

    African Journals Online (AJOL)

    abp

    2016-04-29

    Apr 29, 2016 ... performance hence workplace training is tied to achieving organizational aims and objectives. .... Ethical consideration: Permission to conduct research was sought from the County ..... Everybody Business: Strengthening.

  6. Nitrogen–use efficiency in different vegetation type at Cikaniki Research Station, Halimun-Salak Mountain National Park, West Java

    Directory of Open Access Journals (Sweden)

    SUHARNO

    2007-10-01

    Full Text Available A research about nitrogen–use efficiency (NUE and trees identification was conducted at different vegetation type at Cikaniki, Halimun-Salak National Park, West Java. Plot quadrate methods (20 x 50 m was used to analyze trees vegetation and Kjeldahl methods was used to analyze leaf nitrogen. The width and length of the leaf was also measured to obtain the leaf surface area. The result showed that there are 61 individual trees which consisted of 24 species was identified. The species which have 5 highest important value are Altingia excelsa (64,657, Castanopsis javanica (39,698, Platea latifolia (27,684, Garcinia rostrata (21,151, and Schima walichii (16,049. Futhermore Eugenia lineata (13,967, Melanochyla caesa (12,241, Quercus lineata (10,766, platea excelsa (10,766 have lower important value. Other trees have important value less than 10. Morphological and nitrogen content analyze were done on 4 species : Quercus lineata, G. rostrata, A. excelsa, and E. lineata. Among them, Quercus lineata has highest specific leaf area (SLA (0,01153, followed by G. rostrata (0,00821, A. excelsa (0,00579, and E. lineata (0,00984 g/cm2. The highest number of stomata was found on A. excelsa (85,10/mm2, followed by E. lineata (74,40/mm2, Q. lineata (53,70/mm2, and G. rostrata (18,4 /mm2. The emergent species (A. excelsa and Q. lineata have higher nitrogen content than the underlayer species (G. rostrata and E. lineata. A. excelsa have highest nitrogen use efficiency (28,19% compare to E. lineata (23,81% , Q. lineata (19,09%, and G. rostrata (14,87%. Although not significant, emergen species have higher NUE than underlayer species.

  7. Validity of animal models of type 1 diabetes, and strategies to enhance their utility in translational research.

    Science.gov (United States)

    Graham, Melanie L; Schuurman, Henk-Jan

    2015-07-15

    Type 1 diabetes currently affects 20-40 million people worldwide. Insulin treatment is standard, but a majority of patients still experience glycemic instability and associated comorbidity: there is an unmet medical need for novel therapeutics. Animal models have been indispensable in testing innovative medicinal approaches since the early testing of insulin in dogs almost a century ago. Models include mainly rodents with spontaneous diabetes, or rodents and nonhuman primates in which diabetes is induced by chemicals that are toxic to insulin-producing pancreatic β-cells, or by pancreatectomy. To a less extent models in pigs are used. Rodent models have shown value in studies on pathogenesis and disease prevention, while models in nonhuman primates have translational value in testing β-cell replacement products and immunosuppressives to prevent rejection. Evidently, for many immunosuppressives this validation follows from the close similarity in immune function. Gene therapy approaches are being tested in both rodents and nonhuman primates. We present an overview of models used to answer various research questions, with particular focus on their translational value. This includes a consideration of divergence between the animal model and the clinical condition, and a consideration of the species and model difference in pathogenesis, especially the induction of the diabetic state. Careful attention should be given to managing diabetic animals: outcome measures in the model are highly stress-sensitive and parameters that have potential for confounding should be addressed, i.e., environment, metabolic management, and handling. This review concludes with a few recommendations on how to make animal models more clinical-like.

  8. Research

    African Journals Online (AJOL)

    abp

    2013-02-25

    Feb 25, 2013 ... Of these 56 eyes, the visual acuity in 49 eyes (87.5%) improved with pinhole. Twenty seven pupils had ... (www.afenet.net). Research ... primary basic 1 to 6 and aged 5 to 15 years were included in the study. The United ...

  9. Research

    African Journals Online (AJOL)

    collaboration, but also in less tangible ways affecting quality of research.[5] ... Methods. A 40-hour workshop in biostatistical reasoning was conducted ... test median score was 68% (IQR 62 - 76%), with p<0.0001 for the overall comparison of pre- v. post-scores. ... limitations of a traditional lecture-based mode of instruction.

  10. Research

    African Journals Online (AJOL)

    abp

    2014-03-13

    Mar 13, 2014 ... &Corresponding author: Dr. Oliver Ezechi, Clinical Sciences Division, Nigerian Institute of Medical Research, ... with Hepatitis B and C Virus infection in pregnant HIV positive Nigerians. ... Whether or not HCV directly impacts HIV disease ..... natural history, fibrosis, and impact of antiretroviral treatment:.

  11. Research

    African Journals Online (AJOL)

    understood in the profession, evolved from therapeutic activity (within a medi- cal model ... facilitate students' ability to examine institutional systems that hinder ..... don't have connections with each other … we went to the schools and were told ... for change or conduct action research projects that deal with occupational.

  12. Research

    African Journals Online (AJOL)

    abp

    2015-12-11

    Dec 11, 2015 ... ... Dschang, Cameroon, 2Division of Health Operations Research, Ministry of Public ... This is an Open Access article distributed under the terms of the Creative Commons ... not yet been investigated but may can be explained by weakness of .... Cameroonian market and why not apply for surveillance of.

  13. Research

    African Journals Online (AJOL)

    by teaching them skills on how to acquire and appraise knowledge for a particular ... [3] Similarities have been noted in the roles of lecturers that facilitate learning rather than ..... Student feedback related to facilitators of and barriers to learning. Facilitators of ... 'Sometimes time (clinical, research, social, sport) was limited.'.

  14. Research

    African Journals Online (AJOL)

    raoul

    2011-08-25

    Aug 25, 2011 ... completely replaced animals with computer modeling, manikins and ... distribution, and reproduction in any medium, provided the original ... developed internal guidelines on the use of animals in research in 2004 [13]. ... Only one institution used human cell cultures as a replacement to live animal use.

  15. Research

    African Journals Online (AJOL)

    abp

    2013-08-05

    Aug 5, 2013 ... In 2007, The World Health Organization (WHO) recommended ... are taken nearer to the community through clinical outreach ... Sample size and Sampling procedure ... researchers shared and debated the way each of them understood .... this may involve selling off assets to get the money for transport.

  16. Research

    African Journals Online (AJOL)

    ebutamanya

    2016-04-20

    Apr 20, 2016 ... ... Journal - ISSN 1937-8688. This is an Open Access article distributed under the terms of the Creative ... diabetes mellitus, obesity, family history of premature CHD in a first ... was reviewed and approved by the Hospital's Research and Ethics .... apoptosis of peripheral adipocytes, decreased pre-adipocyte.

  17. Problem Types in Synthetic Organic Chemistry Research: Implications for the Development of Curricular Problems for Second-Year Level Organic Chemistry Instruction

    Science.gov (United States)

    Raker, Jeffrey R.; Towns, Marcy H.

    2012-01-01

    Understanding of the nature of science is key to the development of new curricular materials that mirror the practice of science. Three problem types (project level, synthetic planning, and day-to-day) in synthetic organic chemistry emerged during a thematic content analysis of the research experiences of eight practising synthetic organic…

  18. The benefits of yoga for adults with type 2 diabetes: a review of the evidence and call for a collaborative, integrated research initiative.

    Science.gov (United States)

    de G R Hansen, Elizabeth; Innes, Kim E

    2013-01-01

    Type 2 diabetes (T2DM) is a global public health crisis. Research suggests that yoga holds promise for T2DM management. This article summarizes evidence regarding the efficacy of yoga for T2DM management and encourages the development of an integrated research agenda and a collaborative work group to test it. We present a brief overview of the global rise in T2DM and its consequences and costs, review the evidence regarding the potential benefits of yoga for T2DM management, outline limitations in the literature, discuss possible mechanisms underlying the effects of yoga on T2DM, and suggest how a collaborative, multinational effort by yoga therapist and research communities might contribute to research and inform clinical practice. Yoga protocols that serve T2DM patients and a research framework for creating an evidence base to support the use of yoga for T2DM management are clearly needed.

  19. Threshold for detection of diabetic peripheral sensory neuropathy using a range of research grade monofilaments in persons with Type 2 diabetes mellitus.

    Science.gov (United States)

    Thomson, Mary P; Potter, Julia; Finch, Paul M; Paisey, Richard B

    2008-09-11

    To identify the threshold of reduced sensory perception in Type 2 diabetes mellitus (Type 2 DM) using a range of research grade monofilaments. Three groups of participants were recruited into a between subject, cross-sectional study. Group 1(NEW), persons with Type 2 DM diagnosed for less than 2 years (n = 80); Group 2 (EST) persons with Type 2 DM diagnosed for more than 2 years (n = 91), and Group 3, a Comparison group without Type 2 DM (n = 73), resulted in a total study population, n = 244. Research grade monofilaments (2, 4, 6, 8 and 10-gram) were employed using standardised protocol, at 6 sites on the plantar aspect of both feet. The demographic and anthropometric measures of gender, age, height, weight, body mass index (BMI), blood pressure and duration of Type 2 DM since diagnosis (if applicable) of the participants were analysed. Perception of the research grade monofilaments differed significantly between the 3 groups (p threshold of normal perception, based on 90% of the Comparison group perceiving the 6-gram monofilament at all sites in contrast to 64% of NEW and 48% of EST groups. The 6-gram monofilament was identified as the threshold of normal sensory perception. Inability to perceive the 6-gram monofilament indicates, when using the method described in this study, that diminution of sensory perception is evident. Employing a range of monofilaments, 6, 8 and 10-grams in Type 2 DM foot screening would allow the clinical detection of deteriorating sensory perception and enable implementation of foot protection strategies at an earlier stage than is currently practised.

  20. Statistical Researches for Determination of Satisfaction of Spouses by Marriage and Optimum Type of a Family for its Successful Functioning

    Directory of Open Access Journals (Sweden)

    Victor V. Kovalenko

    2013-01-01

    Full Text Available In the article the application of correlation, analysis of variance for determination of satisfaction of spouses by marriage and optimum type of a family for its successful functioning is considered.

  1. 旅游业态创新发展研究进展%Research Progress on Innovation Development of Tourism Operation Types

    Institute of Scientific and Technical Information of China (English)

    俞海滨

    2011-01-01

    近年来,旅游业态创新作为转型升级发展的一种方式备受中国旅游学界和业界的密切关注。可持续发展理念是旅游业态创新的理论源泉,知识管理是旅游业态创新的重要支撑。从产品开发层面、组织经营层面、产业边界层面等视角对当前中国旅游业态创新研究进行了述评;就未来进一步拓展研究而言,将融入人、社会与自然等元素,把握旅游业态创新研究的体系化;拓展研究领域和深度,突出可操作性;建立旅游业态创新的分析维度与评价方法,加强定量研究;关注旅游生产和消费的低碳化、资源可持续再利用、物联网的应用等重要问题。%In recent years, much attention has been devoted to tourism operation types innovation for the transformation and up- grading of tourism industry. This paper is to review the related research on tourism operation types innovation in China with an emphasis on theory foundations, research viewpoints and future prospects. This paper summarizes that the concept sustainable development is theoretical fountainhead of tourism operation types innovation, and the knowledge management is important sup- port of tourism operation types innovation. This paper discusses that the research on tourism operation types innovation now could be divided into the following viewpoints: product development level; business operation level; industrial boundary level. Further research in the [uture: grasping the systematization of study on tourism operation types innovation integrating with per- son, society, nature and other elements; widening and deepening the research with operability being strengthened; establishing the analysis dimension and evaluation method of tourism operation types innovation, and strengthening quantitative research. In the future, some important issues also should be given special care: low carbonization of tourism production and consumption; re- source sustainable

  2. How can we objectively categorise partnership type? A novel classification of population survey data to inform epidemiological research and clinical practice

    Science.gov (United States)

    Mercer, C H; Jones, K G; Johnson, A M; Lewis, R; Mitchell, K R; Clifton, S; Tanton, C; Sonnenberg, P; Wellings, K; Cassell, J A; Estcourt, C S

    2017-01-01

    Background Partnership type is a determinant of STI risk; yet, it is poorly and inconsistently recorded in clinical practice and research. We identify a novel, empirical-based categorisation of partnership type, and examine whether reporting STI diagnoses varies by the resulting typologies. Methods Analyses of probability survey data collected from 15 162 people aged 16–74 who participated in Britain's third National Survey of Sexual Attitudes and Lifestyles were undertaken during 2010–2012. Computer-assisted self-interviews asked about participants' ≤3 most recent partners (N=14 322 partners/past year). Analysis of variance and regression tested for differences in partnership duration and perceived likelihood of sex again across 21 ‘partnership progression types’ (PPTs) derived from relationship status at first and most recent sex. Multivariable regression examined the association between reporting STI diagnoses and partnership type(s) net of age and reported partner numbers (all past year). Results The 21 PPTs were grouped into four summary types: ‘cohabiting’, ‘now steady’, ‘casual’ and ‘ex-steady’ according to the average duration and likelihood of sex again. 11 combinations of these summary types accounted for 94.5% of all men; 13 combinations accounted for 96.9% of all women. Reporting STI diagnoses varied by partnership-type combination, including after adjusting for age and partner numbers, for example, adjusted OR: 6.03 (95% CI 2.01 to 18.1) for men with two ‘casual’ and one ‘now steady’ partners versus men with one ‘cohabiting’ partner. Conclusions This typology provides an objective method for measuring partnership type and demonstrates its importance in understanding STI risk, net of partner numbers. Epidemiological research and clinical practice should use these methods and results to maximise individual and public health benefit. PMID:27535765

  3. From non-obese diabetic to Network for the Pancreatic Organ Donor with Diabetes: New heights in type 1 diabetes research

    Institute of Scientific and Technical Information of China (English)

    Lourdes; Ramirez; Abdel; Rahim; A; Hamad

    2015-01-01

    Since the discovery of therapeutic insulin in 1922 and the development of the non-obese diabetic spontaneous mouse model in 1980,the establishment of Network for Pancreatic Organ Donor with Diabetes(n POD) in 2007 is arguably the most important milestone step in advancing type 1 diabetes(T1D) research. In this perspective,we briefly describe how n POD is transforming T1 D research via procuring and coordinating analysis of disease pathogenesis directly in human organs donated by deceased diabetic and control subjects. The successful precedent set up by n POD is likely to spread far beyond the confines of research in T1 D to revolutionize biomedical research of other disease using high quality procured human cells and tissues.

  4. Types and quality of physical therapy research publications: has there been a change in the past decade?

    Science.gov (United States)

    Snell, Kaitlyn; Hassan, Ali; Sutherland, Lauren; Chau, Leo; Senior, Tristan; Janaudis-Ferreira, Tania; Brooks, Dina

    2014-01-01

    To describe and compare the type and quality of evidence published in physical therapy (PT) journals during two time periods (2000-2002 vs. 2010-2012) and to explore scientific editors' opinions on changes in the types and quality of articles. A quantitative, longitudinal, retrospective journal review was used to categorize and assess the methodological rigour of items published in four PT journals using the Hedges Project. A quantitative, descriptive, cross-sectional survey explored the opinions of scientific editors. Percentages and frequencies of article types (as defined by the Hedges Project criteria), items passing rigour, and editor responses were calculated. Statistical significance of differences in article type and rigour between the two time periods was determined using Fisher's Exact Test. There was a significant increase in original studies and review articles from 2000-2002 to 2010-2012 (pdesigns, and randomized controlled trials and believed that quality had improved by 2010-2012. From 2000-2002 to 2010-2012, the quality of articles published in PT journals improved and the proportion of original studies and review articles increased.

  5. Genesis types of the Neoproterozoic Molar tooth structures in the southeastern Jilin and eastern Liaoning provinces and its research significances

    Institute of Scientific and Technical Information of China (English)

    2009-01-01

    Molar tooth(briefly called MT) carbonate is one of the Proterozoic carbonates with enigmatic sedimentary structure. According to the morphology of MT,it can be divided into two main genesis-morphology types,i.e.,autochthonous and allochthonous,and each type can be further divided into a series of subtypes. The autochthonous MT can be divided into filamentous(MF1) ,ribbon,nodular and dotted type(MF4) ,in which the ribbon one can be subdivided into simple vertical(MF2) and complex ribbon(MF3) ,broken ribbon by storm in situ(MF5) and MT within nodular limestone(MF6) . Allochthonous MT includes conglomerate clasts and horizontal detritus. Studying on the links between MT and the host rocks on five stratigraphic sections in the southeastern Jilin and eastern Liaoning indicates that the morphology of MT is closely related to host rocks,and seven genetic types by relationships between MT and the host rocks with facies interpretations are classified and discussed in this paper. The sedimentary environments of MT formation will be diverse if their morphologies are different.

  6. Creating Vocabulary Item Types That Measure Students' Depth of Semantic Knowledge. Research Report. ETS RR-14-02

    Science.gov (United States)

    Deane, Paul; Lawless, René R.; Li, Chen; Sabatini, John; Bejar, Isaac I.; O'Reilly, Tenaha

    2014-01-01

    We expect that word knowledge accumulates gradually. This article draws on earlier approaches to assessing depth, but focuses on one dimension: richness of semantic knowledge. We present results from a study in which three distinct item types were developed at three levels of depth: knowledge of common usage patterns, knowledge of broad topical…

  7. CFD simulation of the IAEA 10 MW generic MTR reactor under loss of flow transient

    Energy Technology Data Exchange (ETDEWEB)

    Salama, Amgad, E-mail: asalama@konkuk.ac.kr [Konkuk University, Seoul 143-701 (Korea, Republic of); Atomic Energy Authority, Reactors Department, 13759 Cairo (Egypt); El-Morshedy, Salah El-Din, E-mail: selmorshdy@hotmail.com [Atomic Energy Authority, Reactors Department, 13759 Cairo (Egypt)

    2011-02-15

    Three-dimensional simulation of the IAEA 10 MW generic reactor under loss of flow transient is introduced using the CFD code, Fluent. The IAEA reactor calculation is a safety-related benchmark problem for an idealized material testing reactor (MTR) pool type specified in order to compare calculational methods used in various research centers. The flow transients considered include fast loss of flow accidents (FLOFA) and slow loss of flow accidents (SLOFA) modeled with exponential flow decay and time constants of 1 and 25 s, respectively. The transients were initiated from a power of 12 MW with a flow trip point at 85% nominal flow and a 200 ms time delay. The simulation shows comparable results as those published by other research groups. However, interesting 3D patterns are shown that are usually lost based on the one-dimensional simulations that other research groups have introduced. In addition, information about the maximum clad surface temperature, the maximum fuel element temperature as well as the location of hot spots in fuel channel is also reported.

  8. Validation of deterministic and Monte Carlo codes for neutronics calculation of the IRT-type research reactor

    Science.gov (United States)

    Shchurovskaya, M. V.; Alferov, V. P.; Geraskin, N. I.; Radaev, A. I.

    2017-01-01

    The results of the validation of a research reactor calculation using Monte Carlo and deterministic codes against experimental data and based on code-to-code comparison are presented. The continuous energy Monte Carlo code MCU-PTR and the nodal diffusion-based deterministic code TIGRIS were used for full 3-D calculation of the IRT MEPhI research reactor. The validation included the investigations for the reactor with existing high enriched uranium (HEU, 90 w/o) fuel and low enriched uranium (LEU, 19.7 w/o, U-9%Mo) fuel.

  9. Research on Dewaxing Experiments With New Type of Solvent%新型溶剂脱蜡试验研究

    Institute of Scientific and Technical Information of China (English)

    2015-01-01

    采用新型溶剂进行了轻脱蜡膏生产微晶蜡试验,试验结果表明,过滤速度和微晶蜡产品收率均有提高。%The new type of solvent was used for the test that produced microcrystalline wax by the light dewaxing cerate. The results show that the filtration rate and yield of microcrystalline all can be improved.

  10. Research of heat treatment of low-Co AB5 type hydrogen storage alloys for MH-Ni batteries

    Institute of Scientific and Technical Information of China (English)

    GUO Jinghong; CHEN Demin; LIU Guozhong; YANG Ke; MA Jun

    2003-01-01

    The effects of low-Co AB5 type hydrogen storage alloys prepared by quenching and annealing on the performances of MH-Ni batteries were investigated, and the characteristics of the low-Co AB5 type hydrogen storage alloys were compared with those of the high-Co AB5 type hydrogen storage alloy as well. The results showed that the faster the cooling of the low-Co hydrogen storage alloy is, the better homogeneity of the chemical composition for the alloy and the longer cycle life of the battery are, but the electrochemical discharge capacity and high-rate discharge ability are reduced. The high-rate discharge ability and charge retention of MH-Ni batteries for the conventional as-cast annealed low-Co hydrogen storage alloy were superior to those for the rapidly quenched low-Co hydrogen storage alloy and the high-Co hydrogen storage alloy, but a little inferior in the cycle life.

  11. BioAssay Research Database (BARD): chemical biology and probe-development enabled by structured metadata and result types.

    Science.gov (United States)

    Howe, E A; de Souza, A; Lahr, D L; Chatwin, S; Montgomery, P; Alexander, B R; Nguyen, D-T; Cruz, Y; Stonich, D A; Walzer, G; Rose, J T; Picard, S C; Liu, Z; Rose, J N; Xiang, X; Asiedu, J; Durkin, D; Levine, J; Yang, J J; Schürer, S C; Braisted, J C; Southall, N; Southern, M R; Chung, T D Y; Brudz, S; Tanega, C; Schreiber, S L; Bittker, J A; Guha, R; Clemons, P A

    2015-01-01

    BARD, the BioAssay Research Database (https://bard.nih.gov/) is a public database and suite of tools developed to provide access to bioassay data produced by the NIH Molecular Libraries Program (MLP). Data from 631 MLP projects were migrated to a new structured vocabulary designed to capture bioassay data in a formalized manner, with particular emphasis placed on the description of assay protocols. New data can be submitted to BARD with a user-friendly set of tools that assist in the creation of appropriately formatted datasets and assay definitions. Data published through the BARD application program interface (API) can be accessed by researchers using web-based query tools or a desktop client. Third-party developers wishing to create new tools can use the API to produce stand-alone tools or new plug-ins that can be integrated into BARD. The entire BARD suite of tools therefore supports three classes of researcher: those who wish to publish data, those who wish to mine data for testable hypotheses, and those in the developer community who wish to build tools that leverage this carefully curated chemical biology resource.

  12. Research on the ultrafast fluorescence property of thylakoid membranes of the wild-type and mutant rice

    Institute of Scientific and Technical Information of China (English)

    任兆玉; 许晓明; 王水才; 辛越勇; 贺俊芳; 侯洵

    2003-01-01

    A high yielding rice variety mutant (Oryza sativa L., Zhenhui 249) with low chlorophyll b (Chl b) has been discovered in natural fields. It has a quality character controlled by a pair of recessive genes (nuclear gene). The partial loss of Chl b in content affects the efficiency of light harvest in a light harvest complex (LHC), thus producing the difference of the exciting energy transfer and the efficiency of photochemistry conversion between the mutant and wild-type rice in photosynthetic unit. The efficiency of utilizing light energy is higher in the mutant than that in the wildtype rice relatively. For further discussion of the above-mentioned difference and learning about the mechanism of the increase in the photochemical efficiency of the mutant, the pico-second resolution fluorescence spectrum measurement with delay-frame-scanning single photon counting technique is adopted. Thylakoid membranes of the mutant and the wild-type rice are excited by an Ar+ laser with a pulse width of 120ps, repetition rate of 4MHz and wavelength of 514nm. Compared with the time and spectrum property of exciting fluorescence, conclusions of those ultrafast dynamic experiments are: 1) The speeds of the exciting energy transferred in photo-system I are faster than that in photo-system II in both samples. 2) The speeds of the exciting energy transfer of mutant sample are faster than those of the wildtype. This might be one of the major reasons why the efficiency of photosynthesis is higher in mutant than that in the wild-type rice.

  13. Research on Effective Electric-Mechanical Coupling Coefficient of Sandwich Type Piezoelectric Ultrasonic Transducer Using Bending Vibration Mode

    Directory of Open Access Journals (Sweden)

    Qiang Zhang

    2015-01-01

    Full Text Available An analytical model on electromechanical coupling coefficient and the length optimization of a bending piezoelectric ultrasonic transducer are proposed. The piezoelectric transducer consists of 8 PZT elements sandwiched between four thin electrodes, and the PZT elements are clamped by a screwed connection between fore beam and back beam. Firstly, bending vibration model of the piezoelectric transducer is built based on the Timoshenko beam theory. Secondly, the analytical model of effective electromechanical coupling coefficient is built based on the bending vibration model. Energy method and electromechanical equivalent circuit method are involved in the modelling process. To validate the analytical model, sandwich type piezoelectric transducer example in second order bending vibration mode is analysed. Effective electromechanical coupling coefficient of the transducer is optimized with simplex reflection technique, and the optimized ratio of length of the transducers is obtained. Finally, experimental prototypes of the sandwich type piezoelectric transducers are fabricated. Bending vibration mode and impedance of the experimental prototypes are tested, and electromechanical coupling coefficient is obtained according to the testing results. Results show that the analytical model is in good agreement with the experimental model.

  14. Design and experimental research of a novel inchworm type piezo-driven rotary actuator with the changeable clamping radius.

    Science.gov (United States)

    Zhao, Hongwei; Fu, Lu; Ren, Luquan; Huang, Hu; Fan, Zunqiang; Li, Jianping; Qu, Han

    2013-01-01

    In this paper, a novel piezo-driven rotary actuator with the changeable clamping radius is developed based on the inchworm principle. This actuator mainly utilizes three piezoelectric actuators, a flexible gripper, a clamping block, and a rotor to achieve large stroke rotation with high resolution. The design process of the flexible gripper consisting of the driving unit and the clamping unit is described. Lever-type mechanisms were used to amplify the micro clamping displacements. The amplifying factor and parasitic displacement of the lever-type mechanism in the clamping unit was analyzed theoretically and experimentally. In order to investigate the rotation characteristics of the actuator, a series of experiments was carried out. Experimental results indicate that the actuator can rotate at a speed of 77,488 μrad/s with a driving frequency of 167 Hz. The rotation resolution and maximum load torque of the actuator are 0.25 μrad and 37 N mm, respectively. The gripper is movable along the z direction based on an elevating platform, and the clamping radius can change from 10.6 mm to 25 mm. Experimental results confirm that the actuator can achieve different rotation speeds by changing the clamping radius.

  15. Gas flow research at a plane screw type machine model. Pt. 2; Gasspaltstroemungen in einem ebenen Schraubenmaschinenmodell. T. 2

    Energy Technology Data Exchange (ETDEWEB)

    Kauder, K.; Sachs, R. [Dortmund Univ. (Germany). FG Fluidenergiemaschinen

    1998-12-31

    Gas flows in screw-type machines are effecting the energy conversion of the machine by the leakage mass flows and entropy flows inside the machine. The profile meshing clearance and the housing gap have an essential influence. Here the gas flow at the housing gap with non moving gap bounds is investigated. The used and developed measuring and image analysis technique is explained. Qualitative Schlieren pictures of the flow at three different tooth tips, i.e. gap styles are following to enable a comparison of the flow shapes. The application of a plane screw type machine model with moving gap bounds will be meant to be a contribution towards the investigation of the gas flow conditions in the gaps. (orig.) [Deutsch] Gasspaltstroemungen in Schraubenmaschinen wirken als Leckmassen- und Entropiestroeme erheblich auf die Energiewandlungsguete der Maschine. Besonderen Einfluss haben der Profileingriffs- sowie der Gehaeusespalt. In diesem Beitrag wird die Gehaeusespaltstroemung am Nebenrotor mit feststehender Stroemungsberandung untersucht. Nach Erlaeuterungen zur verwendeten und entwickelten Mess- und Bildverarbeitungstechnik folgen qualitative Schlierenbilder der Stroemung an drei unterschiedlichen Zahnkopf- und damit Spaltformen, die einen Vergleich der Stroemungsformen ermoeglichen. Der naechste Schritt zur Klaerung der Stroemungsverhaeltnisse in den Spalten besteht aus der Einfuehrung eines ebenen Schraubenmaschinenmodells mit drehenden Rotorscheiben. (orig.)

  16. Experimental research on wild-type p53 plasmid transfected into retinoblastoma cells and tissues using an ultrasound microbubble intensifier.

    Science.gov (United States)

    Luo, J; Zhou, X; Diao, L; Wang, Z

    2010-01-01

    The transfection efficiency of wild-type p53 (wtp53) was investigated in retinoblastoma (RB) Y79 cells using an ultrasound microbubble technique. A human RB nude mouse xenograft tumour model was also used to investigate whether this technique could deliver wtp53 into solid tumours. Reverse transcription-polymerase chain reaction (RT-PCR) demonstrated that wtp53 was successfully transfected into Y79 cells in the plasmid with microbubbles and ultrasound group and in the plasmid with liposomes group, but not in the plasmid with ultrasound group or in the untreated control group. Flow cytometry showed that apoptosis was highest in the microbubbles and ultrasound group (25.58%) compared with the plasmid with liposomes group (19.50%), and the other two groups (microbubbles and ultrasound group. This study provides preliminary evidence in support of a potential new approach to RB gene therapy.

  17. Herpes simplex virus type 1-based amplicon vectors for fundamental research in neurosciences and gene therapy of neurological diseases.

    Science.gov (United States)

    Jerusalinsky, Diana; Baez, María Verónica; Epstein, Alberto Luis

    2012-01-01

    Somatic manipulation of the nervous system without the involvement of the germinal line appears as a powerful counterpart of the transgenic strategy. The use of viral vectors to produce specific, transient and localized knockout, knockdown, ectopic expression or overexpression of a gene, leads to the possibility of analyzing both in vitro and in vivo molecular basis of neural function. In this approach, viral particles engineered to carry transgenic sequences are delivered into discrete brain regions, to transduce cells that will express the transgenic products. Amplicons are replication-incompetent helper-dependent vectors derived from herpes simplex virus type 1 (HSV-1), with several advantages that potentiate their use in neurosciences: (1) minimal toxicity: amplicons do not encode any virus proteins, are neither toxic for the infected cells nor pathogenic for the inoculated animals and elicit low levels of adaptive immune responses; (2) extensive transgene capacity to carry up to 150-kb of foreign DNA; i.e., entire genes with regulatory sequences could be delivered; (3) widespread cellular tropism: amplicons can experimentally infect several cell types including glial cells, though naturally the virus infects mainly neurons and epithelial cells; (4) since the viral genome does not integrate into cellular chromosomes there is low probability to induce insertional mutagenesis. Recent investigations on gene transfer into the brain using these vectors, have focused on gene therapy of inherited genetic diseases affecting the nervous system, such as ataxias, or on neurodegenerative disorders using experimental models of Parkinson's or Alzheimer's disease. Another group of studies used amplicons to investigate complex neural functions such as neuroplasticity, anxiety, learning and memory. In this short review, we summarize recent data supporting the potential of HSV-1 based amplicon vector model for gene delivery and modulation of gene expression in primary cultures

  18. A Lithium Abundance Study of Solar-type Stars in Blanco 1 using the 2.1m McDonald Telescope: Developing Undergraduate Research Experiences.

    Science.gov (United States)

    Cargile, Phillip; James, D. J.; Villalon, K.; Girgenti, S.; Mermilliod, J.

    2007-12-01

    We present a new catalog of lithium equivalent widths for 20 solar-type stars in the young (60-100 Myr), nearby (250 pc) open cluster Blanco 1, measured from high-resolution spectra (R 30,000), taken during an observing run on the 2.1m telescope at McDonald Observatory. These new lithium data, coupled with the 20 or so extant measurements in the literature, are used in combination with the results of a recently completed standardized BVIc CCD survey, and corresponding 2MASS near-infrared colors, to derive precise lithium abundances for solar-type stars in Blanco 1. Comparing these new results with the existing lithium dataset for other open clusters, we investigate the mass- and age-dependent lithium depletion distribution among early-epoch (< 1Gyr) solar-type stars, and specifically, the lithium abundance scatter as a function of mass in Blanco 1. Our scientific project is highly synergystic with a pedagogical philosophy. We have instituted a program whereby undergraduate students - typically majoring in Liberal Arts and performing an independent study in Astronomy - receive hands-on research experience observing with the 2.1m telescope at the McDonald Observatory. After their observing run, these undergraduates take part in the reduction and analysis of the acquired spectra, and their research experience typically culminates in writing an undergraduate thesis and/or giving a professional seminar to the Astronomy group at Vanderbilt University.

  19. 新型干细胞的研发及应用进展%Research and development of new type stem cells.

    Institute of Scientific and Technical Information of China (English)

    李占全; 张薇薇

    2011-01-01

    In the past decade, considerable progress has been made in the research of regeneration of cardiomyocytes in ischemic heart disease. Early clinical trials have demonstrated the safety of cell therapy. As stem cell research going further and further, the new type stem cells are constantly developed and stem cell research is expanding. Scientists are inspired by research on iPS cells in the application of stem cell for treatment. Although there are many difficulties in the current study,cell therapy of heart disease may become of the mainstream in future. Here we review the latest relevant research of new type stem cells.%过去10年,心肌细胞的再生疗法治疗缺血性心脏病的研究取得了长足进步.早期临床试验已证明细胞疗法的安全性.随着干细胞研究的深入,新型干细胞不断被研发,干细胞治疗领域不断扩展.诱导多能性干细胞的研发鼓舞了科学家应用干细胞治疗疾病的热情.尽管目前的研究还有许多有待于解决的问题和困难,细胞治疗心脏疾病可能会成为未来方向的主流.文章综述了有关新的干细胞研发及最新进展情况.

  20. Research Progress about the Construction of Type 2 Diabetic Animal Model%Ⅱ型糖尿病动物模型的研究进展

    Institute of Scientific and Technical Information of China (English)

    张玉领; 孙长颢

    2012-01-01

    糖尿病是严重影响人民健康的常见慢性病之一,而Ⅱ型糖尿病占糖尿病总数的90%-95%左右,因此建立合适的Ⅱ型糖尿病动物模型是阐明其发病机制的前提.目前应用于基础研究的糖尿病模型主要有自发性和化学药物实验诱导两大类,其中高能量膳食联合小剂量化学药物诱导的Ⅱ型糖尿病模型诱导方法简单,实验成本低,发病特征以及病理改变类似人类Ⅱ型糖尿病,这种造模方法越来越受到人们重视,给这一领域的研究带来了新的契机和希望.%Diabetes is one of the common chronic diseases which have a serious impact on people's health, and type 2 diabetes accounted for 90% -95% of the total diabetes. Therefore, the establishment of an appropriate animal model of type 2 diabetes is a prerequisite to clarify its pathogenesis. There are mainly two types animal model of type 2 diabetes, which are spontaneously diabetes and experimentally diabetes induced of chemical substances. High-energy diet combined with Low dose chemotherapy drug梚nduced type 2 diabetes attracts more favor, because of its low experiment cost, simply operating and similarly pathological changes to human type 2 diabetes. It also bring new hopes and opportunity to diabetic research.

  1. Research on new type of fast-opening mechanism in steam turbine regulating system and optimization of operation tactic

    Institute of Scientific and Technical Information of China (English)

    Xiao-xiao LI; Xuan-yin WANG; Fu-shang LI

    2008-01-01

    With the analysis on regulating system in 200 MW steam turbine, the necessity of appending the fast-opening function to the original system is set forth and a new type of fast-opening mechanism is devised. The mathematical model of system is built up. With the use of AMESIM software, the displacement curve of the piston, the force curve of the cartridge valve spool, the pressure curve and the flux curve in the regulation process are obtained based on simulation. The performances of three fast-opening systems composed of cartridge valves with different diameters are compared. Based on the analysis on factors that affect the execution time of fast-opening, the dead zone of the fast-opening system is put forward, To overcome the defect, different operation modes are adopted for different zones. The result shows that with the increase of the valve diameter, the regulating time in the dead zone significantly exceeds the fast-opening time in the whole journey. Accordingly, the optimization operation tactic in the dead zone and the qualification conditions are brought forward. The fast-opening system composed of 32 mm cartridge valves is taken as an example with use of the tactic. The simulation result shows that the maximum regulating time is shortened by 509 ms.

  2. Research of Step-down Stress Accelerated Degradation Data Assessment Method of a Certain Type of Missile Tank

    Institute of Scientific and Technical Information of China (English)

    YAO Jun; XU Mingge; ZHONG Weiqiang

    2012-01-01

    The performance degradation rates of the missile tank are generally time-varying functions uneasily evaluated by general classical evaluation methods.This paper develops a segmented nonlinear accelerated degradation model (SNADM) based on the equivalent method of accumulative damage theory,which tackles the problem that product life is difficult to be determined with degradation rate being a function of the variable of time.A segmented expression of the function of population accumulative degradation is derived.And combined with nonlinear function,an accelerated degradation function,i.e.,SNADM is obtained.The parameters of the SNADM are identified by numerical iteration,and the statistical function of degradation track is extrapolated.The reliability function is determined through the type of random process of the degradation distribution.Then an evaluation of product storage life is undertaken by combining the statistical function of degradation track,reliability function and threshold.An example of a missile tank undergoes a step-down stress accelerated degradation test (SDSADT),in which the resuits with the SNADM and the classical method are evaluated and compared.The technology introduced is validated with the resultant coincidence of both evaluated and field storage lives.

  3. Research on effectiveness of coal mine safety supervision system reform on three types of collieries in China

    Institute of Scientific and Technical Information of China (English)

    Quanlong Liu; Xinchun Li; Fuyuan Guan

    2014-01-01

    Coal mine safety supervision system plays an important role in the coal mine safety management in China. However, the current supervision system is established on the basis of learning the advanced experience from other developed countries. It needs to be further improved according to national conditions. Therefore, the effectiveness of coal mine safety supervision system reform on three types of collieries are assessed by using time series analysis method based on comparative analysis of the supervision system before and after the reform in this paper. The regression results show that the structural reform is not conductive to the improvement of coal mine safety situation in the short term, but conductive significantly in the long term. Specifically, the effects in township coal mines are more significant than state-owned key coal mines in the long run, but negative effects also exist in the short term. The negative effects in state-owned key coal mines are non-significant compared with township coal mines. Moreover, the regression results are analyzed from the aspects of the closure policy of illegal small township coal mines at the end of 1998 and shortage of the new supervision system. Finally, the suggestions on improving the new supervision system are put forward based on the above analysis.

  4. Comparing Repository Types - Challenges and barriers for subject-based repositories, research repositories, national repository systems and institutional repositories in serving scholarly communication

    CERN Document Server

    Armbruster, Chris

    2010-01-01

    After two decades of repository development, some conclusions may be drawn as to which type of repository and what kind of service best supports digital scholarly communication, and thus the production of new knowledge. Four types of publication repository may be distinguished, namely the subject-based repository, research repository, national repository system and institutional repository. Two important shifts in the role of repositories may be noted. With regard to content, a well-defined and high quality corpus is essential. This implies that repository services are likely to be most successful when constructed with the user and reader uppermost in mind. With regard to service, high value to specific scholarly communities is essential. This implies that repositories are likely to be most useful to scholars when they offer dedicated services supporting the production of new knowledge. Along these lines, challenges and barriers to repository development may be identified in three key dimensions: a) identific...

  5. Testing the efficacy of culturally adapted coping skills training for Chinese American immigrants with type 2 diabetes using community-based participatory research.

    Science.gov (United States)

    Chesla, Catherine A; Chun, Kevin M; Kwan, Christine M L; Mullan, Joseph T; Kwong, Yulanda; Hsu, Lydia; Huang, Peggy; Strycker, Lisa A; Shum, Tina; To, Diana; Kao, Rudy; Waters, Catherine M

    2013-08-01

    Chinese Americans demonstrate greater prevalence of diabetes than non-Hispanic whites and find standard diabetes care disregards their cultural health beliefs. Academic researchers and Chinatown agencies collaborated to culturally adapt and test an efficacious cognitive-behavioral intervention using community-based participatory research. Using a delayed-treatment repeated-measures design, 145 adult Chinese immigrants with Type 2 diabetes completed treatment. Immediate benefits of treatment were evident in the improvement (p diabetes self-efficacy, diabetes knowledge, bicultural efficacy, family emotional and instrumental support, diabetes quality of life, and diabetes distress. Prolonged benefits were evident in all changed variables 2 months post-intervention. The CBPR approach enabled the development of a culturally acceptable, efficacious behavioral intervention, and provides a model for working with communities that demonstrate health disparities.

  6. Safety analysis for operating the Annular Core Research Reactor with Cintichem-type targets installed in the central region of the core

    Energy Technology Data Exchange (ETDEWEB)

    PARMA JR.,EDWARD J.

    2000-01-01

    Production of the molybdenum-99 isotope at the Annular Core Research Reactor requires highly enriched, uranium oxide loaded targets to be irradiated for several days in the high neutron-flux region of the core. This report presents the safety analysis for the irradiation of up to seven Cintichem-type targets in the central region of the core and compares the results to the Annular Core Research Reactor Safety Analysis Report. A 19 target grid configuration is presented that allows one to seven targets to be irradiated, with the remainder of the grid locations filled with aluminum ''void'' targets. Analyses of reactor, neutronic, thermal hydraulics, and heat transfer calculations are presented. Steady-state operation and accident scenarios are analyzed with the conclusion that the reactor can be operated safely with seven targets in the grid, and no additional risk to the public.

  7. Research aimed at improving both mood and weight (RAINBOW) in primary care: A type 1 hybrid design randomized controlled trial.

    Science.gov (United States)

    Ma, Jun; Yank, Veronica; Lv, Nan; Goldhaber-Fiebert, Jeremy D; Lewis, Megan A; Kramer, M Kaye; Snowden, Mark B; Rosas, Lisa G; Xiao, Lan; Blonstein, Andrea C

    2015-07-01

    Effective interventions targeting comorbid obesity and depression are critical given the increasing prevalence and worsened outcomes for patients with both conditions. RAINBOW is a type 1 hybrid design randomized controlled trial. The objective is to evaluate the clinical and cost effectiveness and implementation potential of an integrated, technology-enhanced, collaborative care model for treating comorbid obesity and depression in primary care. Obese and depressed adults (n = 404) will be randomized to usual care enhanced with the provision of a pedometer and information about the health system's services for mood or weight management (control) or with the Integrated Coaching for Better Mood and Weight (I-CARE) program (intervention). The 12-month I-CARE program synergistically integrates two proven behavioral interventions: problem-solving therapy with as-needed intensification of pharmacotherapy for depression (PEARLS) and standardized behavioral treatment for obesity (Group Lifestyle Balance(™)). It utilizes traditional (e.g., office visits and phone consults) and emerging care delivery modalities (e.g., patient web portal and mobile applications). Follow-up assessments will occur at 6, 12, 18, and 24 months. We hypothesize that compared with controls, I-CARE participants will have greater improvements in weight and depression severity measured by the 20-item Depression Symptom Checklist at 12 months, which will be sustained at 24 months. We will also assess I-CARE's cost-effectiveness and use mixed methods to examine its potential for reach, adoption, implementation, and maintenance. This study offers the potential to change how obese and depressed adults are treated-through a new model of accessible and integrative lifestyle medicine and mental health expertise-in primary care.

  8. Researching research

    DEFF Research Database (Denmark)

    Pais, Alexandre; Valero, Paola

    2012-01-01

    We discuss contemporary theories in mathematics education in order to do research on research. Our strategy consists of analysing discursively and ideologically recent key publications addressing the role of theory in mathematics education research. We examine how the field fabricates its object...... to a reflexivity of research on its discourses and effects. Furthermore, they enable us to present a clear distinction between what has been called the sociopolitical turn in mathematics education research and what we call a positioning of mathematics education (research) practices in the Political....

  9. Improving the performance of the Egyptian second testing nuclear research reactor using interval type-2 fuzzy logic controller tuned by modified biogeography-based optimization

    Energy Technology Data Exchange (ETDEWEB)

    Sayed, M.M., E-mail: M.M.Sayed@ieee.org; Saad, M.S.; Emara, H.M.; Abou El-Zahab, E.E.

    2013-09-15

    Highlights: • A modified version of the BBO was proposed. • A novel method for interval type-2 FLC design tuned by MBBO was proposed. • The performance of the ETRR-2 was improved by using IT2FLC tuned by MBBO. -- Abstract: Power stabilization is a critical issue in nuclear reactors. The conventional proportional derivative (PD) controller is currently used in the Egyptian second testing research reactor (ETRR-2). In this paper, we propose a modified biogeography-based optimization (MBBO) algorithm to design the interval type-2 fuzzy logic controller (IT2FLC) to improve the performance of the Egyptian second testing research reactor (ETRR-2). Biogeography-based optimization (BBO) is a novel evolutionary algorithm that is based on the mathematical models of biogeography. Biogeography is the study of the geographical distribution of biological organisms. In the BBO model, problem solutions are represented as islands, and the sharing of features between solutions is represented as immigration and emigration between the islands. A modified version of the BBO is applied to design the IT2FLC to get the optimal parameters of the membership functions of the controller. We test the optimal IT2FLC obtained by modified biogeography-based optimization (MBBO) using the integral square error (ISE) and is compared with the currently used PD controller.

  10. Research status of identification of Brucella species/types%布鲁氏菌种/型鉴别的研究现状

    Institute of Scientific and Technical Information of China (English)

    闫飞; 郑文艳; 张专才; 曲芬

    2014-01-01

    Brucellosis is a kind of zoonosis which is caused by members of the genus Brucella. World Organization for Ani-mal Health lists it as an important infectious disease. In recent years, the morbidity of brucellosis has been rising. Application of molecular biology techniques to the research of Brucella species/types is of important significance. This article summarizes the re-search progress of identification of Brucella species/types, which provides evidence for judging and predicting epidemic dynamics, studing epidemic characteristics and making reasonable and effective prevention and control counter-measures.%布鲁菌病是由布鲁氏菌引起的一种人畜共患病,世界动物卫生组织将其列为重要传染病,近些年发病率呈上升趋势。应用分子生物学技术进行布鲁氏菌种/型分类的研究具有重要意义。本文通过总结近年来布鲁氏菌种/型鉴定的研究进展,为今后判断预测疫情动态、研究流行特点以及制定合理有效的防治对策提供重要的理论依据。

  11. Current Progress in the Research on the Type H Effectors of Xanthomonas%黄单胞杆菌Ⅲ型效应子研究进展

    Institute of Scientific and Technical Information of China (English)

    车晋英; 李岩强; 王春连; 赵开军

    2011-01-01

    Many pathogenicities of Xanthomonas depend on a conserved type Ⅲ secretion system which injects type Ⅲ effectors into the plant cell, causing the host's immune response or susceptibility. Here, we presented an overview about the classification of type Ⅲ effectors from Xanthomonas and the main function of Avrbs3,AvrRxv/YopJ, XopN, XopD family. The effector proteins with enzymatic functions in the interaction of Xanthomonas with its host plants were highlighted, for example, the SUMO protease activity of XopD; Effectors of the AvrBs3 family can mimic plant transcriptional activators and manipulate the plant transcriptome; XopN suppresses PAMP-triggered immune responses during Xcv infection. Some of those expertly studied in depth and the interaction with their host factors were reviewed in detail. Finally, the impact of the type Ⅲ effectors'research on plant disease resistance genetic engineering and the future prospects of research direction about the type Ⅲ effectors were discussed.%许多黄单胞杆菌通过Ⅲ型分泌系统将效应子注入到寄主细胞中,引起寄主的免疫反应或感病.最近的研究提供了大量的关于Ⅲ型效应子作为致病因子或激发子同寄主互作的实验数据.笔者综述了黄单胞杆菌Ⅲ型效应子的分类及avrbs3、AvrRxv/YopJ、XopN、XopD家族的主要功能,重点介绍了Ⅲ型效应子的酶活性功能在同寄主互作过程中发挥的重要作用,如XopD的SUMO化作用;AvrBs3家族效应子在调节寄主基因转录方面的作用;XopN抑制PAMP介导的植物免疫反应的功能等.论文还对一些研究深入的Ⅲ型效应子及其与寄主的互作进行了比较详细的评述,讨论Ⅲ型效应子的研究对于植物抗病基因工程的影响及重要意义,并对Ⅲ型效应子的研究方向进行了展望.

  12. 1型神经纤维瘤病的基因学研究进展%The advanced genomics research of neurofibromatosis type 1

    Institute of Scientific and Technical Information of China (English)

    柯屹峰; 郝瑞; 张虹

    2010-01-01

    Neurofibromatosis type 1 is a term of Von Recklinghausenan.It is an autosomal dominant inherited disease which derived by neural crest cell.Prevalence of this disease is 1/3000 1/3500 and is a disease with the highest mutation rate.The pathogenesis of neurofibromatosis type 1 is associated with the deficiency of NF1 gene.Recently,the genetics and genomics research of neurofibromatosis make a great progress.With the development of gene linkage and position cloning technology,the gene sequence of neurofibromatosis type 1 has been found.Recent research of genetics and genomics of NF1 and the structure and function,abnormal expression,the relation of genotype and phenotype,the mutation sensitivity domain of NF1 gene were reviewed.%1型神经纤维瘤病(NF1)又称为Von Recklinghausen病,为起源于神经嵴细胞分化异常而导致多系统损害的一种常染色体显性遗传病,患病率为1/3000~1/3500,其发病与NF1基因的缺失有关.近年来对NF遗传和基因学的研究取得了很大进展,通过基因连锁和"定点克隆"技术获得了该病基因序列、突变及其表达信息.对近年在NF1基因和遗传学方面的研究成果、NF1基因的结构和功能、NF1基因的异常表达、该病基因型和表现性的关系、基因的易突变区域等进行综述.

  13. 氧化锌材料p型掺杂研究进展%Recent Research on p-type Doping of ZnO

    Institute of Scientific and Technical Information of China (English)

    谭蜜; 张红; 李万俊; 秦国平; 阮海波; 孔春阳

    2016-01-01

    氧化锌(ZnO)是 II-VI 族直接带隙化合物半导体材料,室温下禁带宽度为3.37 eV,激子束缚能高达60 meV,是制造蓝紫外发光、探测以及激光器件的理想材料。高质量 n 型和 p 型 ZnO 以及同质 p-n 结的制备是实现器件化的关键。目前,n 型 ZnO 的制备技术已趋于成熟,但高质量稳定的 p 型 ZnO 的缺乏已成为制约其器件化的瓶颈。在过去的十余年里,通过国内外科研工作者的不懈努力,在理论和实验上都取得了显著的成果。本文主要概述了 ZnO 材料的 p 型掺杂、p 型导电机制以及 p-ZnO 基光电器件的研究进展,同时初步探索了 ZnO 材料 p 型导电稳定性问题。%Zinc oxide (ZnO),a typical direct wide bandgap (3.37 eV)semiconductor,has attracted an increasing interest tothe optoelectronics field.Its large exciton binding energy of 60 meV endows it with high radiative recom-bination efficiency,a unique advantage in light emitting and lasing devices.The fabrications of high quality n-and p-type ZnO as well as p-n junction are the key steps to realize these applications.although the techniques of fabri-cated n-type ZnO has been well developed,the reliable p type doping of the material remains a major challenge to optoelectronic applications,despitethe fact that p-doping of ZnO has been improved and that marked results in ex-periment and theory have been achieved during the past ten years.In this review,we examined the recent research progress in p-type doping of ZnO,including the p-type performance,the mechanism of p-type conduction,and p-ZnO based photoelectric devices,and so on.Moreover,based on the challenges of the current researches,we sum-marized the factors that may affect the p-type doping,especially the stability of p-type ZnO materials.

  14. 治疗2型糖尿病药物最新研究进展%Latest research progress of drugs for treating type 2 diabetes mellitus

    Institute of Scientific and Technical Information of China (English)

    杨彬

    2015-01-01

    Type 2 diabetes mellitus is an endocrine metabolic diseases with insulin resistance and relatively insufficient secretion of insulin caused by metabolism disorder of glucose, fat, and protein. Traditional oral hypoglycemic drugs included sulfonylureas, α-glucosidase inhibitor, biguanides, insulin sensitizer, and glinides. In recent years, with discovery of new mechanism, new drugs for type 2 diabetes mellitus have occurred, such as DDP-4 and GLP-1. This paper elaborates research progress of some other new drugs for type 2 diabetes mellitus, including type 2 sodium glucose co-transporters, 11β-HSD-1 inhibitor, GRP119, and PTP1B inhibitor.%2型糖尿病是一种因葡萄糖、脂肪、蛋白质代谢紊乱并最终导致胰岛素抵抗及胰岛素相对分泌不足的内分泌代谢疾病。传统口服降糖药物分别有磺脲类、α-葡糖糖苷酶抑制剂、双胍类、胰岛素增敏剂、格列奈类。近几年随着新的作用机制的发现,出现了多种治疗2型糖尿病的新型药物,如DDP-4和GLP-1。本文章主要阐述其他最新2型糖尿病治疗药物研究进展,包括输送器第二型抑制剂(SGLT2)、11β-HSD-1抑制剂、GRP119、PTP1B抑制剂。

  15. Design and Research of Load-type 3D Micro Platform%负载型三自由度微动平台设计与研究

    Institute of Scientific and Technical Information of China (English)

    陈琪; 连磊磊; 刘丽娟

    2013-01-01

    The research significance of 3D mobile platform with load capacity was introduced and a mobile device with certain bearing capacity and 3D positioning was designed,including the analysis of its moving accuracy and displacement detection.The realization of displacement detection technology can benefit mobile platform' s mobile positioning and provides the technical reference for load-type positioning instrument and equipment.%设计了一种具备一定承栽能力和三维空间定位的移动装置,并对其移动精度和位移检测技术进行了研究与分析.通过位移检测技术的实现,实现了移动平台的空间移动定位功能,为负载型的定位仪器和设备提供了技术参考.

  16. [Type Code of the pharmaceutical industry for the protection of personal data in the field of clinical research and pharmaceutical surveillance].

    Science.gov (United States)

    Fraguas, Lourdes; Francés, Mercedes; Riesgo, Patricia

    2010-01-01

    The Type Code establishes uniform criteria in the sectoral application of the Organic Law on Data Protection (LOPD) and its implementing Regulation increases the guarantee of its compliance and reduces the level of uncertainty as to its implementation. Two key activities in the pharmaceutical industry are considered, namely clinical research and pharmacovigilance, all scenarios that take place in the daily practice of these activities are developed and procedures for the use of personal data and irreversible dissociation are established, with these last being exempt from the application of data protection legislation. It develops a protocol that includes the guidelines to follow with regard to the exercise of rights of access, rectification, cancellation and opposition exercised by those affected and stipulates the supervisory functions of the Code by the Monitoring Committee.

  17. An Innovative Passive Residual Heat Removal System of an Open-Pool Type Research Reactor with Pump Flywheel and Gravity Core Cooling Tank

    Directory of Open Access Journals (Sweden)

    Kwon-Yeong Lee

    2015-01-01

    Full Text Available In an open-pool type research reactor, the primary cooling system can be designed to have a downward flow inside the core during normal operation because of the plate type fuel geometry. There is a flow inversion inside the core from the downward flow by the inertia force of the primary coolant to the upward flow by the natural circulation when the pump is turned off. To delay the flow inversion time, an innovative passive system with pump flywheel and GCCT is developed to remove the residual heat. Before the primary cooling pump starts up, the water level of the GCCT is the same as that of the reactor pool. During the primary cooling pump operation, the water in the GCCT is moved into the reactor pool because of the pump suction head. After the pump stops, the potential head generates a downward flow inside the core by moving the water from the reactor pool to the GCCT and removes the residual heat. When the water levels of the two pools are the same again, the core flow has an inversion of the flow direction, and natural circulation is developed through the flap valves.

  18. CRISPR在细菌分型和进化中的研究进展%Progress in CRISPR Research on Bacteria Typing and Evolution

    Institute of Scientific and Technical Information of China (English)

    王建; 邱少富; 宋宏彬; 孙岩松

    2013-01-01

      Clustered regularly interspaced short palindromic repeats(CRSIPR) are recently discovered and wide⁃spread in the genomes of many bacteria and almost archaea, which provide acquired immunity against foreign DNA. The polymorphism of CRISPR makes it possible to be used as the ideal locus of bacteria typing and evolu⁃tion study. In this review, the basic structure of CRISPR as well as the research progress of CRISPR on bacteria typing and evolution were introduced.%  规律成簇的间隔的短回文重复序列(CRISPR)是近年发现的一类存在于古细菌和细菌基因组内的结构,该结构可以使细菌获得对外源DNA如质粒和噬菌体的免疫,同时由于其结构的多态性,也可作为细菌分型和进化研究的位点。简要综述了CRSIPR系统的基本结构,及其在分型和进化应用方面的研究进展。

  19. Progress in Research of New Human Enterovirus Types%新型人类肠道病毒的研究进展

    Institute of Scientific and Technical Information of China (English)

    陈鹏; 陶泽新; 王海岩; 宋艳艳; 王显军; 徐爱强

    2013-01-01

    More and more new human enteroviruses (HEVs) types were identified with the broad application of the molecular serotyping methods for enteroviruses. Since enterovirus 71 (EV71) was first reported in 1969, numerous epidemic outbreaks associated with new enteroviruses have occurred all around the world, and pose a significant threat to public health . The epidemics of hand, foot and mouth disease (HFMD) caused by EV71 infection in China have raised great concern of global scholars. This paper reviewed research progress in recent years of the molecular typing, evolution, epidemiology, and patho-genesis attributable to new enterovirus types.%随着人类肠道病毒(Human enteroviruses,HEVs)分子定型方法的广泛应用,越来越多的新型HEVs被发现.自1969年肠道病毒71型(EV71)首次报道后,新型HEVs已在世界范围内引起多次暴发流行,带来了严重的公共卫生问题,特别是自2007年以来在中国大陆发生的EV71所致手足口病的广泛流行,引起国内外学者的高度关注.本文对近些年有关新型HEVs分子分型、进化、流行病学特征、致病性等方面的研究进展进行了综述.

  20. Research Progress in Type Ⅰ Pullulanase from Bacteria%细菌Ⅰ型普鲁兰酶的研究进展

    Institute of Scientific and Technical Information of China (English)

    孙晓晨; 初晓宇; 伍宁丰

    2012-01-01

    Type I pullulanase typically hydrolyzes the a-1, 6 glucosidic linkages of pullulan or branched oligosaccharides in an endo-way to produce maltotriose or liner oligosaccharides, respectively. This enzyme plays a very significant role in the food, chemistry and medical industries, because they can degrade different saccharides with other glycoside hydrolases producing various products. At present, studies on this enzyme focus not only on screening novel strains, but also on obtaining type I pullulanase with proper properties to suit industrial production. This review summarizes the research progress on type I pullulanase from bacteria in some fields, such as catalytic properties, separation and cloning of gene, producing enzyme by microorganism. The industrial application of this enzyme and prospect of its research are also discussed.%Ⅰ型普鲁兰酶以内切的方式专一性作用于普鲁兰糖或者支链多糖的α-1,6糖苷键,生成产物麦芽三糖或线性多糖.在工业应用中,Ⅰ型普鲁兰酶与其他糖苷水解酶协同作用于不同糖类底物,可得到类型多样的终产物,因此在食品、化工、制药等行业中有很重要的作用.目前对Ⅰ型普鲁兰酶的研究不仅包括筛选高产酶的菌株,还需得到酶学性质优良的酶蛋白,以适合工业生产工艺.综述了细菌来源的Ⅰ型普鲁兰酶的研究概况,包括酶学性质、基因的分离与克隆、微生物生产,并讨论了该酶在工业生产中的应用及其研究前景.

  1. IMPROVEMENT OF ORGANIZATIONAL STRUCTURES AND CONTROLLING OF PERSONNEL IN COMPANIES OF THE TYPE CALLED "RESEARCH INSTITUTE" IN THE ROCKET AND THE SPACE INDUSTRY

    Directory of Open Access Journals (Sweden)

    Mukhin V. V.

    2015-05-01

    Full Text Available Improvement of the organizational structures can increase the efficiency of enterprises. Controlling of personnel in companies such as "Research Institute" is a tool to support personnel decisions; it contributes to the strategic goals and tactical objectives. This article describes the main types of organizational structures, their properties, sociometric research as a tool for management, the stages of implementation of model of controlling of personnel in human resource management system for companies such as "Research Institute". Controlling of personnel is in regulation of HR processes, benchmarking, monitoring the implementation of the goals, taking into account the costs of implementing improved management systems, etc. It aims to determine the quality, efficiency and optimality of specific mechanisms, technologies and methods for the implementation of the HR function. Objectively, the volume of realization of the HR function depends on the presence of a certain quantities of material, labor, financial and other resources, on the objectives of the enterprise at different stages of the life cycle, as well as the number and qualifications of personnel. The quality of realization of the HR function depends on the level of its top-management's understanding of the importance of human resource management in the enterprise, as well as of the skill level of middle management. Controlling of HR function allows us to create an information base for effective management decisions that can help us to optimize the system of personnel management in the circumstances of the market environment, which is a necessary basis for the successful development of enterprises working in the field of high technology products and services

  2. Human endogenous retrovirus type W (HERV-W) in schizophrenia: a new avenue of research at the gene-environment interface.

    Science.gov (United States)

    Leboyer, Marion; Tamouza, Ryad; Charron, Dominique; Faucard, Raphaél; Perron, Hervé

    2013-03-01

    Provide a synthetic review of recent studies evidencing an association between human endogenous retrovirus-W (HERV-W) and schizophrenia. Bibliography analysis and contextual synthesis. Epidemiological studies suggest that the aetiology of schizophrenia is complex and involves a complex interplay of genetic and environmental factors such as infections. Eight percentof the human genome consists of human endogenous retroviruses (HERV), and this part of the genome was previously thought to be without importance, but new research has refuted this. HERVs share similarities with viruses and it is assumed that HERVs are present in the genome as a result of retroviruses infecting germ line cells many million years ago. A specific type of HERVs, called HERV-W, has through several recent studies been associated with schizophrenia. Elevated transcription of HERV-W elements has been documented, and antigens of HERV-W envelope and capsid proteins have been found in blood samples from patients. Viruses that have been implicated in pathology of schizophrenia, such as herpes and influenza, have been shown to activate HERV-W elements, and such activation has been associated with elevated biomarkers of systemic inflammation. New research indicates that HERV-W may be an important genetic factor interplaying with the environmental risk factor of infections and that, through this, HERV-W may be important for disease pathogenesis. A lifelong scenario of a detrimental interaction between infectious agents and HERV-W genes may decipher the actual development and course of schizophrenia. Further research is needed to find out if specific treatment strategies could reduce the expression of HERV-W and if this will be associated with remission.

  3. Research on Selections of Bridge Site and Type of Hutiaoxia Jinsha River Bridge%虎跳峡金沙江大桥方案研究

    Institute of Scientific and Technical Information of China (English)

    刘伟; 陈克坚; 游励晖

    2013-01-01

    Research purposes:The Hutiaoxia Jinsha River Bridge is the key project of Lijiang-Xianggelila Railway and is located in the sensitive environmental and high seismic intensity region with the active fault.The reasonable bridge site and type should be selected for this bridge on consideration of the railway alignment,environment protection,topography,geological condition and the plan of hydraulic engineering on the midstream of the river.Research conclusions:(1)Using the deck type steel braced arch at the No.8 bridge site(416m) of the Hutaioxia Jinsha River Bridge is the best engineering plan.Using the steel truss suspension bridge at No.27 bridge site (98 + 660 +98 m) can remain the condition for the hydroelectric plan of river and can get the better economic and social benefits.(2) The deck type steel braced arch has features of the good load bearing capacity,good rigidity and nice looking and is suitable for the high mountain and deep valley area,but it produces the impact on the water storage and shipping under bridge because the arch rib is installed on bottom of the structure.(3) The steel truss suspension bridge has the features of the fine anti-seismic performance and good rigidity to meet the train requirement.(4) The research result can provide the reference to the type selection of the large span railway bridge in mountain and deep valley area.%研究目的:虎跳峡金沙江大桥为丽香铁路的重点控制性工程.大桥桥址位于环境敏感区、高烈度地震区及断裂发育带,需要综合线路走线、环保、地形、地质情况及金沙江中游水电开发规划的影响,选择虎跳峡金沙江大桥的合理桥位及桥式方案.研究结论:(1)虎跳峡金沙江大桥的8号桥位416 m上承式钢桁拱桥是最优的工程方案,27号桥位(98+660 +98)m钢桁梁悬索桥可以为规划中的水电开发预留条件,整体上经济、社会效应更好;(2)上承式钢桁拱桥承载能力高、刚度大、造型优美,适用于

  4. Research organizations

    DEFF Research Database (Denmark)

    Larsen, Bøje; Aagaard, Peter

    in Copenhagen - we argue that a post-rational form of research activity is emerging which revert these features. We term this new type of research "enchanted research", "sciencetainment" and "Mode2-b research". The factors that facilitate this development include the boring style of conventional research......, growing competition for research funds, more project funding compared to institutional funding and a demand for accountability. Countervailing forces also exist, however....

  5. “白烟型”热液喷流岩研究进展%Progress of Research on "White Smoke Type"Exhalative Hydrothermal Rocks

    Institute of Scientific and Technical Information of China (English)

    焦鑫; 柳益群; 周鼎武; 汪双双; 南云; 周宁超; 杨焱钧

    2013-01-01

    The " black smoker" hydrothermal activities in the bottom of the sea/lake and its related diagene-sis, mineralization and paleontology, which are mentioned in both modern and historical geology, have become a hotspot in the multi-disciplinary study nowadays. But comparatively speaking, the relative research on " white smoke type" exhalative hydrothermal rocks is obviously inadequate. Based on reading a large number of domestic and foreign literatures, combined theory with authors' practical research work, this paper reviews the historic and present situation of the study of exhalative hydrothermal rocks. In this article, the authors put emphasis on introducing the progress on the origin of dolomite, as a symbolic low-temperature hydrothermal mineral. The authors believe that the "white smoke type" exhalative hydrothermal dolostone is the typical sample of primary dolostone. A-vailable information indicates that the layers of "white smoke type" exhalative rocks which has been reported, that is, Xiagou Formation in Jiuxi basin and Lucaogou Formation in Santanghu basin, are important hydrocarbon source rock in their respective regions. According to this information, the following issues are worthy to be taken into consideration.①The special environment of the hydrothermal activities and their related thermophilic bacteria and food chain makes the organic matter, which could provide material basis for the generation of oil and gas, enriched. ② Mantle-originated material is likely to bring mantle-originated hydrocarbons. ③Hydrothermal activities would increase the geotemperature of sedimentary basin generally, as a result, it may accelerate the maturity of hydrocarbon source rocks. Lastly, the authors give their questions and proposals for further research in this field.%现代和地质历史中的海底、湖底的“黑烟囱型”热液活动及相关成岩、成矿和古生物活动已成为当今多学科的研究热点,而与“白烟型”热液喷流岩

  6. 肠道病毒71型疫苗研究进展%Research Progress of the Enterovirus Type 71 Vaccine

    Institute of Scientific and Technical Information of China (English)

    李燕; 刘燕敏; 梁晓峰

    2011-01-01

    近几年来,手足口病(Hand,Foot and Mouth Disease,HFMD)受到越来越多的关注.肠道病毒71型(Enterovirus Type 71,EV71)是引起HFMD的病原体之一.由于HFMD重症或死亡病例以EV71为主要病原,且该病尚无特效的治疗药物,因此EV71疫苗成为预防HFMD有效的措施.国内外已有灭活疫苗、减毒活疫苗、亚单位疫苗、病毒样颗粒和脱氧核糖核酸疫苗等多种尝试,但这些疫苗仅在动物模型中进行了评价,尚未实施临床试验.现将EV71疫苗研究进展进行综述.%Recent years, hand, foot and mouth disease(HFMD)caused more and more attention. Enterovirus type 71 (EV71)is one of pathogen caused HFMD. EV7I vaccine is an effective measure to prevent HFMD because of most severe cases and deaths caused by EV7, and there is no effective drugs so far. There are several vaccine candidates! Including inactivated whole virus vaccine?live-attenuated virus vaccine, subunit vaccine, virus-like particle and deoxyribonucleic acid vaccines, which have been trial and evaluated in animals. Clinical trial, however, has not been conducted. The research progress of EV71 vaccine was reviewed in this paper.

  7. Electronic health record use to classify patients with newly diagnosed versus preexisting type 2 diabetes: infrastructure for comparative effectiveness research and population health management.

    Science.gov (United States)

    Kudyakov, Rustam; Bowen, James; Ewen, Edward; West, Suzanne L; Daoud, Yahya; Fleming, Neil; Masica, Andrew

    2012-02-01

    Use of electronic health record (EHR) content for comparative effectiveness research (CER) and population health management requires significant data configuration. A retrospective cohort study was conducted using patients with diabetes followed longitudinally (N=36,353) in the EHR deployed at outpatient practice networks of 2 health care systems. A data extraction and classification algorithm targeting identification of patients with a new diagnosis of type 2 diabetes mellitus (T2DM) was applied, with the main criterion being a minimum 30-day window between the first visit documented in the EHR and the entry of T2DM on the EHR problem list. Chart reviews (N=144) validated the performance of refining this EHR classification algorithm with external administrative data. Extraction using EHR data alone designated 3205 patients as newly diagnosed with T2DM with classification accuracy of 70.1%. Use of external administrative data on that preselected population improved classification accuracy of cases identified as new T2DM diagnosis (positive predictive value was 91.9% with that step). Laboratory and medication data did not help case classification. The final cohort using this 2-stage classification process comprised 1972 patients with a new diagnosis of T2DM. Data use from current EHR systems for CER and disease management mandates substantial tailoring. Quality between EHR clinical data generated in daily care and that required for population health research varies. As evidenced by this process for classification of newly diagnosed T2DM cases, validation of EHR data with external sources can be a valuable step.

  8. 闭合式蚊香盘的实验研究%Laboratory Research for Closure Type Mosquito Coil Incense Utensil

    Institute of Scientific and Technical Information of China (English)

    汤永康; 任樟尧

    2001-01-01

    Objective:To research for closure type mosqu ito coil incense utensil. Methods:To detect the dust, inc ense utensil and volatile noxious. Results:This paper re ported that both the closure type and the opening type mosquito coil incense ut ensil. The volatile noxious to be one's health of the matter, decrease 67.49 %,u=9.42,P<0.05;≥0.5μm dust 67 771.75/L and 71 811.84/L, decrease 5.63%,χ2 =40.77,P<0.05;≥0 .5μm dust as time going on was decrease,r=0.988 8,t =11.47, P<0.05;simulation locale test results of the biom etrics , unconsciousness rate : 1 hour 32% and 28%, 3 hour both th e closure type and the opening type mosquito coil incense utensil 100 %.%目的:降低盘式蚊香使用过 程中产生的挥发性有害物质和尘埃粒子数量,减少室内空气污染,提高生活环境质量,保障 人体健康。方法:通过测定燃烧过程中释放出污染物 质的吸附率、空气中尘埃粒子数和对生物药效的影响等,对闭合式蚊香盘与常规使用的敞开 式蚊香盘进行对照观察。结果:闭合式新蚊香盘与对照组的效果无 明显差异;挥发性物质过滤吸收率达到67.49%(u=9.42,P<0.05 );两组在燃烧过程中产生≥0.5μm尘埃粒子数,平均增量分别为67 771.75和 71 811.84个/L,比对照组减少5.63%(χ2=40.77,P<0.05) ;尘埃粒子数随着点燃时间的延长而减少(r=0.988 8,t=11.47,P <0.05);模拟现场生物药效测试,1h击倒率分别为32%和28%,3h均为100%。结论: 闭合式蚊香盘可降低67.49%的污染物质、5.63%≥0.5μm的尘埃粒子数,具有应用前景。

  9. Research in Complex Type Deep Hole Drilling Machine%复合型深孔加工机床的研究

    Institute of Scientific and Technical Information of China (English)

    刘来章; 张文强; 刘铸

    2014-01-01

    现代深孔加工机床加工方式分为外排屑(枪钻)和内排屑(BTA钻)两种,他们的供油通道和排屑通道相反、钻孔直径范围大小不同。研究了双主轴双导向型、单主轴双导向型、单主轴单导向型3种结构的复合型深孔加工机床,比较了这3种结构机床的优缺点。采用BTA和枪钻两种加工方式,可完成复杂机械零件较大孔径范围的深孔加工。%There are two processing methods of modern deep hole drilling machine,outside chip removing (gun drilling)and internal chip removing (BTA drilling). The oil supply channels and chip removing channels of them were opposite,and the borehole diameter range of them was different. Three structural types of complex deep holes drilling machines as the double spindle double orien-ted,single spindle double oriented and single spindle single oriented were researched. Larger diameter range of deep holes of compli-cated machinery parts can be machined,by using both methods of BTA drilling and gun drilling.

  10. Research Progress in Intestinal-type Fatty Acid Binding Protein%肠型脂肪酸结合蛋白研究进展

    Institute of Scientific and Technical Information of China (English)

    王家胜; 杨强

    2012-01-01

    肠型脂肪酸结合蛋白( Ⅰ-FABP,FABP2)是脂肪酸结合蛋白超家族中的重要成员,主要参与机体对脂肪酸的吸收、转运、以及在细胞器内的再分布及利用.近年研究表明,FABP2与代谢性疾病、炎症性疾病、肠组织缺血损伤等密切相关,不但是肠组织损伤的敏感性标志,而且可以作为炎症严重程度的评价指标,并可能成为某些代谢性疾病的药物治疗靶点.%Intestinal-type fatty acid binding protein (I-FABP, FABP2 ) is a key member of the FABP super family, participating in the organism's absorption,transferring,intracellular redistribution and use of fatty acids. Recent research has demonstrated that FABP2 is closely related with metabolic diseases,inflammatory diseases and ischemic injuries of intestinal tissue. It is not only a sensitive sign of intestinal injuries but also a severity evaluation indicator of inflammation. What's more,it can probably be a pharmacotherapy target of some metabolic diseases.

  11. Function type computer virus running technology analysis and research%功能型计算机病毒运行技术分析与研究

    Institute of Scientific and Technical Information of China (English)

    李俊; 李佟鸿

    2012-01-01

    本文提出了功能型计算机病毒的概念,给出了功能型计算机病毒的一般结构。对功能型计算机病毒的运行技术进行了分析。对功能型计算机病毒的研究有助于了解此类病毒的运行机理和特点,对防治此类病毒具有十分重要的意义。%This paper proposes a functional concept of computer virus,gives the function type of computer virus in the general structure.On the function of computer virus operation technology are analyzed.On the function of computer virus research contributes to the understanding of the virus running mechanism and characteristic,on the prevention and treatment of this kind of virus has very important significance.

  12. Research Progress of Plant Type Microbial Fuel Cell%植物型微生物燃料电池研究进展

    Institute of Scientific and Technical Information of China (English)

    许鹏; 许丹; 张义; 夏世斌; 吴振斌

    2014-01-01

    The combination of the microbial fuel cell with aquatic plants(PMFC)is a new low -carbon environmental pro-tection technology ,it is an important innovation in the field of water pollution control and has raised widespread concern in the world .This paper reviews the current research situation about PMFC ,summarizes the principles of different types of PMF ,analyzes the factors influencing the power production of the PMFC and finally prospects the future application ,as well as working directions of this system .%微生物燃料电池(MFC )与水生植物相耦合,构成植物型微生物燃料电池(PMFC )系统是一项全新的低碳环保产能技术,是水污染控制领域的一项重要技术创新,已在国内外引起广泛关注。对植物型MFC的研究现状进行了综述,总结了不同类型PMFC的工作原理并分析了影响其产电的因素,最后对该系统未来的应用及研究方向进行了展望。

  13. Facts about Type 2

    Medline Plus

    Full Text Available ... En Español Type 1 Type 2 About Us Online Community Meal Planning Sign In Search: Search More ... Generation of Brilliant Researchers Diabetes Pro: Professional Resources Online We Support Your Doctor Clinical Practice Guidelines Patient ...

  14. Types of biological variables.

    Science.gov (United States)

    Mayya, Shreemathi S; Monteiro, Ashma D; Ganapathy, Sachit

    2017-06-01

    Identification and description of variables used in any study is a necessary component in biomedical research. Statistical analyses rely on the type of variables that are involved in the study. In this short article, we introduce the different types of biological variables. A researcher has to be familiar with the type of variable he/she is dealing with in his/her research to decide about appropriate graphs/diagrams, summary measures and statistical analysis.

  15. 1998 research cooperation project. Research cooperation on environment-compatible type water resource effective-utilization system; 1998 nendo kankyo taiogata mizushigen yuko riyo system ni kansuru kenkyu kyoryoku

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1999-03-01

    For the purpose of securing water stably and preventing water pollution in the Philippines, R and D were carried out on a wastewater treatment and water reclamation and reuse system which is easy to operate and maintain and low in cost through the research cooperation between the Philippine Industrial Technology Development Institute and Japan. According to the survey result of statistical data concerning water pollution load structure by industrial wastewater classified by the industry in the Philippines, enumerated are the food manufacturing industry, paper pulp manufacturing industry, and the textile dyeing industry as those greatly affecting water pollution in BOD exhaust and wastewater, etc. Consequently, with Ram Food Product Co. of vegetable processing and Solid Mill Co., of textile dyeing as plants to be studied, a wastewater treatment test was performed in a laboratory scale. From the result of the test, the pilot plant was basically designed to have 'anaerobic + aerobic treatment + tertiary treatment' for the treatment process, with an one-tank type UASB method used as the anaerobic treatment, with a sand filtration + activated charcoal treatment as the tertiary treatment, and with the cost effectiveness for water reuse set to be examined. (NEDO)

  16. Research Advance on Thyroid Dysfunction in Type I Diabetes Meilitus%Ⅰ型糖尿病患者甲状腺功能异常的研究

    Institute of Scientific and Technical Information of China (English)

    李红蔚; 宋岩; 林来祥

    2011-01-01

    糖尿病是由多种因素引起的一种全身性代谢异常综合征,I型糖尿病患者中甲状腺功能异常的发生率高于正常人群.两者具有共同的遗传免疫学基础,表现为激素水平、自身抗体表达等方面的异常,且其表现与年龄、性别、糖尿病病程、血糖控制情况等有关.两者合并发生与细胞毒性T细胞相关抗原-4基因、蛋白酪氨酸磷酸酶非受体型22基因、人类白细胞抗原HLA基因及Xp的FOXP3基因等基因多态性关系密切.血清抗体的检测有助于提早发现疾病,尽早治疗.目前两者合并发生的机制尚未完全明了,需开展更多研究.%Diabetes mellitus is a systemic metabolic dysfunction syndrome caused by many factors, and patients with type Ⅰ diabetes mellitus have higher occurrence rate of thyroid dysfunction compared to normal population.The two diseases have common immunogenetics basis, which exhibits disorders in hormone levels, auto-antibodies expression and other aspects and they are related to age, sex, duration of diabetes, plasma glycemic control, etc.The combined occurrence is closely related to gene polymorphism, such as cytotoxic T cell associated antigens-4 gene, protein tyrosine phosphatase non-receptor type 22 genes, HLA genes and the FOXP3 gene of Xp.Detection of serum antibodies contributes to early discovery and treatment of this disease.The mechanism hasn't been fully understood currently, more researches need to be carried out.

  17. The FTO gene is associated with an atherogenic lipid profile and myocardial infarction in patients with type 2 diabetes:A Genetics of Diabetes Audit and Research Study in Tayside Scotland (Go-DARTS) Study

    OpenAIRE

    2009-01-01

    Background-Common variation in the fat mass and obesity (FTO)-related gene is associated with increased body fat and susceptibility to type 2 diabetes. We hypothesized that this would also associate with metabolic phenotypes of insulin resistance and increased risk of cardiovascular morbidity and mortality. Methods and Results-FTO rs9939609 genotype was determined in 4897 patients with type 2 diabetes in the prospective Genetics of Diabetes Audit and Research Study in Tayside Scotland study. ...

  18. 基于暂降类型判断的短路故障类型识别研究%Research of Short-Circuit Fault Type Recognition Based on Sag Type Detection

    Institute of Scientific and Technical Information of China (English)

    2013-01-01

    Different types of short-circuit faults can lead to different sag phenomena. This paper analyzes the relationships between the fault types and sag types, the propagation laws of sags and the characteristics of sag magnitudes and sequence components. Then based on judging the voltage sag type it proposes the method of short-circuit fault type recognition is proposed, which applies symmetrical component method. Finally, the feasibility of the proposed method is demonstrated through simulation and actual case analysis.%  不同短路故障类型会引起不同的电压暂降类型,本文分析了故障类型与暂降类型之间的关系、电压暂降的传递规律,以及暂降类型的幅值及其对称分量的特点。基于电压暂降事件录波数据,提出了一种通过判断不同电压暂降类型来进行短路故障类型识别的方法,并通过仿真和实例分析验证了该方法的可行性。

  19. Control and Research of New Type Electromechanical Retarder%新型机电式缓速器的控制与研究

    Institute of Scientific and Technical Information of China (English)

    郭大军; 唐应时; 左佳; 李靖

    2012-01-01

    介绍一种新型机电式ACBS(Anti-lock Central Braking System)汽车缓速器.研究ACBS的力矩可调及控制技术等问题,ACBS属于接触式减速装置,制动力矩小可调,会对车辆平顺性造成影响;由于接触温升较快,长时间制动时会出现制动鼓、摩擦衬片的热衰退现象.为解决上述问题,根据ACBS受力模型以及热力学模型,提出了基于微机控制的气动方案及水冷解决方案.仿真结果表明,通过微机对制动力矩的控制,能够很好的实现ACBS的平稳制动,水冷系统能极大地提高ACBS的稳定性.研究结果对重型车辆以及工程机械的制动系统设计具有一定参考价值.%This article introduces a new type electromechanical Anti - lock Central Braking System (ACBS) retarder in automobile. The adjustable breaking torque and control technology of ACBS have been researched. The ACBS belongs to contact deceleration device, and the braking torque is unadjustable, which will cause an impact on riding qualities. Because the contact temperature rises faster, long time brake will generate heatfade phenomenon on brake drum and friction facing. To solve the above problems, according to ACBS bearing model and thermodynamics model, the paper put forward a pneumatic solution based on microcomputer control and the water cooling solution. The simulation and experiment results show that using the microcomputer to control the braking torque can realize the ACBS smooth braking, and the water cooling system can greatly improve the stability of the ACBS. The results of the study have certain reference value for the design of heavy vehicles and engineering machinery braking system.

  20. Research Progress on Vaccines of Porcine Circovirus Type 2%猪圆环病毒2型疫苗的研究进展

    Institute of Scientific and Technical Information of China (English)

    王一平; 郭龙军; 唐青海; 刘长明

    2012-01-01

    Porcine circovirus type 2 (PCV2) has been recognized as the primary causative agent of postweaning multisystemic wasting syndrome (PMWS) , which results in tremendous economic losses in swine industry worldwide. PCV2 infection leads to impaired immune system in animals, severe immunosuppression, as well as co-infection and secondary infection among various bacteria and viruses, which will bring about tremendous obstacles in diagnosis and therapy. It is an effective way to control PCV2 infection by vaccination. The study on PCV2 vaccines is one of the hot research areas. To date, the inactivated vaccines of PCV2, subunit vaccines and chimeric virus vaccines are commercially available in North America and Europe, and the inactivated vaccines of PCV2 have also been developed in China. Development and application of the commercial PCV2 vaccines play a significant role in the prevention and control of PCV2 associated diseases effectively. However, the commercial PCV2 vaccines could not totally block the transmission of PCV2 a-mong pigs and eliminate the virus in pigs. Therefore, it is the main research trend to develop efficient and inexpensive genetically engineered vaccines such as live vector vaccines, DNA vaccines and marker vaccines in the future. This article summarizes the characteristics and efficacy of currently commercial PCV2 vaccines, and reviews the recent achievements on PCV2 vaccines inclu-ding live vector vaccines, DNA vaccines and marker vaccines. It may become a useful contributor to the next generation vaccines for control of PCV2-associated diseases.%猪圆环病毒2型(PCV2)是引起断奶仔猪多系统衰竭综合征(PMWS)的主要病原,给全球养猪业造成了巨大经济损失.PCV2感染可以破坏动物机体的免疫系统,造成严重的免疫抑制,容易诱发多种细菌及病毒的混合感染与继发感染,给疾病的诊断和治疗带来巨大的困难.疫苗免疫接种是防控PCV2感染的有效手段,有关PCV2疫苗的研

  1. Osteogenesis imperfecta type V

    DEFF Research Database (Denmark)

    Rauch, Frank; Moffatt, Pierre; Cheung, Moira;

    2013-01-01

    Osteogenesis imperfecta (OI) type V is an autosomal dominant bone fragility disorder that we had described a decade ago. Recent research has shown that OI type V is caused by a recurrent c.-14C>T mutation in IFITM5. In the present study, we assessed all patients diagnosed with OI type V at our...

  2. Stres, A ve B Tipi Kişilik Yapısı ve Bunlar Arasındaki İlişki Üzerine Bir Araştırma(Stress, Type A And Type B Personalıty Charasterıstıcs And A Research On The Relatıonshıp Between Stress And The Two Types

    Directory of Open Access Journals (Sweden)

    Ufuk DURNA

    2004-01-01

    Full Text Available People are exposed to the stress due to various reasons. We can classify these reasons into two groups: organizational reasons and extraorganizational reasons. Today many techniques which aim to cope with stress have been developed. Stress could be managed and controlled by physiological, psychological, behavioral, environmental techniques.Type A individuals are extremely competitive, highly work oriented, impatient and sensitive to time. Type B individuals are with less conflict with both other people and time and have a more balanced and relaxed life style.Our research attempts to explore relationship between the individual stress level and Type A and Type B personality. It has been found that, individuals who have a high stress level show mostly Type A personality characteristics.

  3. Knowledge Types Used by Researchers and Wool Producers in Australia under a Workplace Learning Typology: Implications for Innovation in the Australian Sheep Industry

    Science.gov (United States)

    Thompson, Lyndal-Joy; Reeve, Ian

    2011-01-01

    This paper reports on research into the learning aspects of adopting integrated parasite management practices for sheep (IPM-s) applying a workplace learning framework. An analysis of four primary data sources was conducted; a postal survey of Australian wool producers, a Delphi process with IPM-s researchers, focus groups and interviews with wool…

  4. Treatment of varicocele infertility men patients of different Chinese medical syndrome types by integrative medicine treatment selection:a primary research

    Institute of Scientific and Technical Information of China (English)

    倪凯

    2013-01-01

    Objective To explore the optimal treatment selection for treating varicocele(VC) male infertility patients accompanied with oligozoospermia or azoospermia of different Chinese medical syndrome types by comparing the efficacies of integrative medicine.Methods One hundred and

  5. Research for the Working Method of Live Replacing the L-type Insulator String on ±800kV DC Transmission Lines

    Science.gov (United States)

    Li, Jinliang; Wang, Zhigang; Lei, Dongyun; Yang, Miao; Xia, Zengming; Xiang, Yun; Yan, Yu; Liu, Zhiguo

    2017-07-01

    It would be hard to be repaired in the case of a power outage if the ±800kV ultra high voltage DC (UHVDC) transmission line was put into operation, so live working is the guarantee for its security and stability. Insulator strings of duplex L-type are widely used in UHVDC small angle towers. In the meantime, the tower structure and the insulator strings’ arrangement type is different than the V-type. In order to ensure the security and stability of the transmission line, this paper presents a method of live replacing the duplex L-type insulators based on the actual parameter of the UHVDC L tower type and develops apparatus as a complementary supporting by mechanics analysis. In order to ensure the safety of working staff, the safe distance and combined gap of the hanging basket method are checked. Safety precautions are also proposed in the paper by the calculation of body surface field strength of the persons doing live working in the finite element method. It is shown by the field application that the live working task of replacing the L-type insulator strings can be accomplished successfully by the method put forward in this paper, which provides reference for the following live working on the UHV transmission line.

  6. 基于OpenType的国际音标字库研究与实现%Research and Realization on International Phonetic Alphabet Based on Open Type

    Institute of Scientific and Technical Information of China (English)

    斯日古楞; 木仁

    2014-01-01

    国际音标在语言学的学习和研究中应用广泛,因其字母和符号繁多,经常会出现显示不够美观甚至出现混乱之处。该文主要探讨和研究国际音标符号特点,OpenType 字库及其高级排版特性,并给出了一种采用 OpenType 字库技术解决国际音标 TrueType 字库中存在的附加符(Diacritics)出现位置偏差、附加符与元音或辅音叠加等影响字符显示问题的解决方案。%International phonetic alphabets are widely used in language learning and the study on lin-guistics .But the display of the alphabets is not often perfect or even is mixed because of a variety of letters and symbols .This paper mainly investigates the features of International Phonetic Alphabet symbols , Open Type Font as well as its characteristics of the advanced typesetting .It is proposed that the affecting appearance problems ,such as location deviation of diacritics in International Phonetic Alphabet True Type Font ,overlap of diacritics and vowels or consonant ,would be solved down with Open Type Font skills .

  7. Research on Quality Improvement for Essential Oil of Chinese Rose Kushui - Type%改进苦水玫瑰精油质量途径初探

    Institute of Scientific and Technical Information of China (English)

    卢乐华; 吴亮; 张宁

    2016-01-01

    Rose essential oil samples of Kushui - type (produced in two years) and Damascena - type were analyzed by gas chromatography - mass spectrometry (GC - MS). The chemical components and their relative contents in two types were compared, the difference between Kushui - type rose oils produced in different years and these two types were discussed systematically. Meanwhile, large - scale cultivation, standardization and quality control in processing were proposed, it was significant for the improvement and stability of Chinese Kushui - type rose oil's quality.%通过气相色谱-质谱联用法(GC-MS)对不同年份的苦水玫瑰精油和大马士革玫瑰精油的化学成分进行分析,从它们在化学成分及相对含量上的差异比较出发,较系统地探讨了苦水玫瑰精油与大马士革玫瑰精油,以及不同年份苦水玫瑰精油之间的质量差异,提出了玫瑰种植规模化、加工规范化和产品质量控制规格化的思路,对于提升苦水玫瑰精油的品质及保持产品质量的稳定性具有参考价值.

  8. 某型特种弹药意外发火研究%The Research of a Type of Special Ammunition Accidental Firing

    Institute of Scientific and Technical Information of China (English)

    苌军红; 李便花; 潘会平; 王鹏; 王飞

    2015-01-01

    特种弹药作为一种特殊效应的武器,作战时具有不可替代的作用,小型特种弹药携带方便,操作简单,功能明确。特种弹药随身携行时,弹药的安全性尤为重要。产品的安全性一方面来自产品的设计,另一方面来自生产工艺,随着“以人为本”安全理念的深入,产品设计与工艺制造同样重要。以实际案例为切入点,从产品结构、装配特点等方面对某型特种弹药在振动试验中意外发火进行了分析,对各因素排查,并对影响因素进行了试验验证。研究表明,形成该产品振动意外发火的原因是产品在外观、装配正确性检查和重新装配时,拉火绳被夹在发射筒体与保护套之间,振动试验时,保护套发生位移,增加了拉火绳拉力,使发火丝发生位移,发火丝上的药剂与火帽磨擦导致产品发火。该结果也为产品装配过程应按章操作提出了警示。%As a special effect weapon combat,special ammunition has an irreplaceable role.The small special ammuni-tion is convenient to carry,has simple operation and the clear function.When special ammunition carried along,the safety is very important.Safety aspects come from design of product,on the other hand,from the production process,with the“people-oriented”safety concept deeply,when product design and manufacturing process are equally important.Take the case as the breakthrough point,carry on the analysis to a certain type of special ammunition in the vibration test of acciden-tal firing from the product structure and assembly features,then influence factors are verified.Research shows that the cause of the product vibration accidental firing is the product in appearance,assembly and correctness checking re assembly. When lanyard is sandwiched between the launch tube body and the protection cover in vibration test,protective sleeve is in displacement,pull rope tension is increased,the ignition wire is

  9. GJM 型棒式搅拌磨机的研发与应用%Research and application of GJM bar type stirred mill

    Institute of Scientific and Technical Information of China (English)

    孙小旭; 卢世杰; 何建成; 刘佳鹏

    2016-01-01

    为解决普通球磨机在石墨再磨流程中存在的效率低、能耗高的问题,在阐述石墨再磨设备设计要求的基础上,研制了GJM型棒式搅拌磨机。研发过程中,以相似放大为基本设计原则,明确了高径比在1∶1~2.5∶1之间的圆柱形筒体结构;确定了搅拌棒在搅拌主轴上呈2~10层、每层1~8根的螺旋上升式布置型式,采用了电机、减速机直接传动方式。同时,运用力学知识分析了磨机内部的受力情况和运动形态,通过轴功率的计算确定了磨机装机功率;分析了特定能量输入下应力强度对产品粒度的影响方式,得到了应力强度在(0.1~0.5)×10-4N・m时容易获得最优产品粒度的结论。最终,将此磨机和普通球磨机同时应用于石墨再磨流程中,取得了较普通球磨机节能25%左右的试验结果,表明其在石墨行业的应用潜力巨大。%In order to solve the problem of high energy consuming and low efficiency of ordinary ball mill in graphite regrinding process ,under the premise of stating the design requirements of regrinding equipment ,developing the GJM bar type stirred mill .During the researching and developing ,considering similar amplification as basic design principle ,determining the cylinder tank with height‐diameter ratio is 1∶1~2 .5∶1 ,confirming the 2~10 layers‐each layer 1~8 stirring arms spiral‐up layout style on the stirring shaft ,using the motor and reducer box direct transmission way .Meanwhile ,we apply the knowledge of mechanics to analyze the force status and movement form ,and using the calculation of shaft power to confirm the installed power of mill .We analyze the influence way to the product size of stress intensity under the specific energy input ,obtaining the conclusion of stress intensity in the (0 .1~0 .5) × 10-4 N ・ m can gain the best product size easily .In the end ,we put the mill and ball mill in the graphite

  10. 应用型本科院校定位及应用型人才培养研究%Research on Applied Type of Undergraduate Colleges and Universities and Cultivation of Applied Talents

    Institute of Scientific and Technical Information of China (English)

    吴现立

    2016-01-01

    探讨应用型本科院校定位及应用型人才的内涵,指出应用型人才与研究型人才的区别、应用型本科院校应用型人才培养与高职高专技能型人才培养的区别,提出应用型本科院校转型发展的任务和应用型人才培养的措施。%This paper explored the position and the connotation of the applied type of undergraduate colleges and u-niversities and pointed out the differences between applied type of talented students and those of the researching type,the differences between cultivating the applied type of undergraduates of the colleges and universities and those of the skilled type of talents trained in higher vocational and technical colleges,and finally proposed the transformational and developing tasks for the applied type of undergraduate institutions and measures for training the applied type of talents.

  11. Degludec, a new ultra-long-acting basal insulin for the treatment of diabetes mellitus type 1 and 2: advances in clinical research.

    Science.gov (United States)

    Muñoz Torres, Manuel

    2014-03-01

    Degludec is the most recent molecule of the ultra-long-acting basal insulin analogues approved for human use. It forms soluble multihexamers which after subcutaneous injection are converted into monomers, and are thus slowly and continuously absorbed into the bloodstream. This absorption mechanism confers degludec an ultra-long and stable action profile, with no concentration peaks. This paper discusses the most recent studies in patients with type 1 and 2 diabetes mellitus, which showed degludec to be non inferior in decreasing HbA1c, ensuring optimum glycemic control similar to that achieved with insulin glargine or detemir. Degludec also had an improved safety profile, as it was associated to a significantly lower rate of nocturnal hypoglycemia in both types of diabetes and to a potentially lower overall hypoglycemia rate in type 2 DM. Degludec also opens the possibility to use more flexible regimens.

  12. Research misconduct

    Energy Technology Data Exchange (ETDEWEB)

    Gilbert, F.J. E-mail: f.j.gilbert@abdn.ac.uk; Denison, A.R

    2003-07-01

    Good research practice is important to the scientific community. An awareness of what constitutes poor practice is important. Various types of research misconduct are defined in this article. The extent of research misconduct in the field of radiology has been assessed by contacting five English language radiology journals. Redundant or duplicate publication has been reported infrequently, Radiology (1), American Journal of Roentgenology (3), Clinical Radiology (3), British Journal of Radiology (2) and European Radiology (1). The issue of how the radiology community might tackle research misconduct is discussed with reference to guidance from the Medical Research Council, the Wellcome Trust and the Committee of Publication Ethics.

  13. WY♀-YY♂型罗非鱼繁殖体系研究%Research of propagation system of WY♀-YY♂ type tilapia

    Institute of Scientific and Technical Information of China (English)

    杨永铨; 张海明; 陈远生

    2013-01-01

    In order to realize the natural reproduction of supermale tilapia, WY type female were selected continuously according to hereditary basis and germplasm standard of Oreochromis Niloticus, and combined with YY type supermale to construct WY♀-YY♂ propagation system of O. Nilolicus. The results showed that WY♀-YY♂ propagation system can re-product YY type supermale and WY type female naturally, and can maintain sex balance, and supermale can be selected without testcross. This kind of propagation system could realize scale production of supermale and the transforming of breeding from three-line combination to two-line combination.%为实现超雄罗非鱼的自然繁殖,按照尼罗罗非鱼(Oreochromis Niloticus)的遗传基础和种质标准,不断选育尼罗WY雌性鱼,然后与尼罗YY超雄鱼相组合,形成尼罗罗非鱼WY♀-YY ♂繁殖体系.研究结果显示:WY♀-YY ♂繁殖体系能自然繁殖YY超雄鱼和WY雌鱼;能保持性比平衡;不用测交直选超雄鱼.此种繁殖体系可使超雄鱼规模化制种,实现三系配套转变为二系配套制种.

  14. Research on Three-Phase Magnetic Valve Type Controllable Reactor%三相磁阀式可控电抗器的研究

    Institute of Scientific and Technical Information of China (English)

    李海洋; 赵国生

    2011-01-01

    提出了一种新型的三相磁阀式可控电抗器,并介绍了其结构及原理,对其进行了电磁分析。%The new three-phase magnetic valve type controllable reactor is presented.Its structure and principle are introduced.Its electromagnetic problems are analyzed.

  15. A Research-Based Undergraduate Organic Laboratory Project: Investigation of a One-Pot, Multicomponent, Environmentally Friendly Prins-Friedel-Crafts-Type Reaction

    Science.gov (United States)

    Dintzner, Matthew R.; Maresh, Justin J.; Kinzie, Charles R.; Arena, Anthony F.; Speltz, Thomas

    2012-01-01

    Students in the undergraduate organic laboratory synthesize tetrahydro-2-(4-nitrophenyl)-4-phenyl-2"H"-pyran via the Montmorillonite K10 clay-catalyzed reaction of p-nitrobenzaldehye with methanol, 3-buten-1-ol, and benzene. The synthesis comprises an environmentally friendly tandem Prins-Friedel-Crafts-type multicomponent reaction (MCR) and sets…

  16. Related research of blood glucose, blood lipid and serum cystatin C and lower-extremity arterial disease in type 2 diabetic mellitus

    Institute of Scientific and Technical Information of China (English)

    Juan Zeng; Jie Ou; Yun-Mei He; Chun-Yu Cai

    2016-01-01

    Objective:To explore the relationship between levels of blood glucose, blood lipid and serum cystatin C and lower-extremity arterial disease in type 2 diabetic mellitus so as to provide the basis for the prevention and treatment of the disease.Methods:A total of 240 cases of patients with type 2 diabetic mellitus receiving physical examinations in our hospital from March 2014 to March 2015 were selected and divided into three groups. The control group was consisted of type 2 diabetes patients without lower-extremity arterial disease, the observation group 1 included type 2 diabetes patients with mild or moderate lower-extremity arterial disease, and the observation group 2 was formed by type 2 diabetes patients with severe lower-extremity arterial disease. Each group contained 80 cases. Then, the heights, weights, waist and hip circumferences of patients in the three groups were determined and the body mass index (BMI) and waist to hip ratio (WHR) were calculated; the fasting blood glucose (FBG), fasting insulin (FINS), insulin resistance index (HOMA-IR), 2 h postprandial blood glucose (2 h PG) and glycosylated hemoglobin (HBA1c) in two groups were detected; and the levels of serum total cholesterol(TC), triglyceride (TG), low density lipoprotein cholesterol (LDL-C), high density lipoprotein cholesterol (HDL-C), apolipoprotein A1 (apoA1), apolipoprotein B (apoB) and cystatin C (CysC) in two groups were also tested.Results:Compared with the control group, the WHR, FBG, HOMA-IR, 2 h PG, HBA1c, LDL-C, apoB and CysC all increased significantly, and the differences were statistically significant. Besides, there were statistically significances existing between the observation groups 1 and 2. What’s more, the serum levels of TC, HDL-C, TG and apoA1 in the observation groups were not significantly different from those of the control group.Conclusions: There is a close relationship between blood glucose, blood lipid, serum cystatin C level and lower-extremity arterial

  17. 农村新型社区教育促进农村新型社区建设探究%Research of New-type Community Education Promoting the New-type Community Construction in Rural Areas

    Institute of Scientific and Technical Information of China (English)

    侯龙真; 何爱霞

    2015-01-01

    The construction of the new-type rural community sticks to people-oriented and sustainable development principles, so the construction of rural community needs to be improved, and the problems of the relatively outdated concepts of the community residents, the low level of cul-tural quality and the employability skills of community labors, as well as the poor environment in ru-ral community, needs to be solved.The new-type rural community education is a significant meas-ure to deal with the current situation, which includes the follows:to update the concepts of residents to construct a learning-mode community; to carry out employment training for the rural transfor-ming labors to improve their employability skills, and to develop environmental education to achieve sustainable development of new-type rural community.%农村新型社区建设坚持以人为本、可持续发展的理念,该理念为我国农村社区建设提出了新的要求。一直以来,我国农村社区建设面临着社区居民观念相对陈旧,社区劳动力文化素质、就业技能普遍较低,农村社区环境问题突出等问题。鉴于此,开展农村新型社区教育是解决当前问题的重要途径。农村新型社区教育要做到:更新社区居民观念,构建学习型农村社区;开展农村转移劳动力就业培训,提高其就业技能;开展社区环保教育,实现社区的可持续发展。

  18. Research and Analysis about Type A Character of Students in Hanzhong City%关于汉中市A型性格学生的研究及分析

    Institute of Scientific and Technical Information of China (English)

    惠锦

    2011-01-01

    It is very important to research the type A character for our mental and physical health, which closely contact with medicine.To find out the proportion of Type A to all students of Hanzhong, the author chose 300 subjects randomly from them who would finish the Type A and Type B personality test.Finally there are 42.52% of the Type A of them, thus, the author puts forward some measures to improve the quality of people's lives which could overcome the harm the Type A bringing.%研究A型性格对我们的身心健康至关重要,它与医学也有密切联系,为了解汉中市学生中A型性格所占比重,笔者随机抽取汉中市300名学生进行A型B型性格测验问卷调查,结果发现被试中42.52%为A型性格,由此,笔者提出了克服A型性格给我们生活带来危害的有效措施,以期提高人们的生活质量.

  19. Progress in research of the targets and new drugs resisting type I hypersensitivity%抗Ⅰ型变态反应的药物作用靶点及其新药研发

    Institute of Scientific and Technical Information of China (English)

    邓政; 蒲小平

    2013-01-01

    Many patients suffer from a frequently occurred disease in clinic, type Ⅰ hypersensitivity, which might cause death if it were serious. Because available drugs have various kinds of defects, the research and development of new drugs for type Ⅰ hypersensitivity has been a common theme to international pharmaceutical companies. Focusing on the cellular and molecular biologic pathogenesis of type Ⅰ hypersensitivity, this review summarized the possible action targets of drugs resisting type Ⅰ hypersensitivity, and the progress on research and development of new drugs from the point of view on the new medicine research and development. This review also pointed out the progress tendency on research of the targets and new drugs in the coming five years.%Ⅰ型变态反应是临床上常见的一类困扰患者生活质量的疾病,严重的可致死.现有抗Ⅰ型变态反应药物存在着各种问题,研制该类新药已成为国际各大制药公司的共同话题.本文将从新药研发的角度,围绕I型变态反应发病的细胞与分子生物学机制,就抗I型变态反应的药物可能的作用靶点及新药研发进展做一综述,并指出了未来5年的发展趋势.

  20. Research of new AB type hydrogen storage materials that can be used as a negative electrode in nickel -metal hydride battery; Recherche de nouveaux composes intermetalliques hydrurables de type AB utilisables comme electrode negative d`accumulateur nickel-hydrure

    Energy Technology Data Exchange (ETDEWEB)

    Jordy, Ch.

    1994-12-15

    The aim of this work is to determine new AB type hydrogen storage materials that can be used as a negative electrode in nickel-metal hydride battery. The main requested solid-gas hydrogenation properties are as follows : a reversible capacity higher than 400 mAh/g and a plateau pressure close to 0, 01 MPa at 25 deg C. Binary intermetallic compounds have been selected according to their high hydrogen capacity. The thermodynamic properties of the hydride have to be adjusted by partial substitution of the A and/or B elements. The selected binary intermetallic rate to the substitution was based on known thermodynamic models and on criteria on hydrogen atom occupation in interstitial sites. The only alloys, which could have interest, are the one which are homogeneous. Amongst them, the compounds Ti(Fe{sub 1-x}) where M=Ni,Co,Mn,Cr, showed a solid-gas capacity higher than 400 mAh/g and a plateau pressure close to 0,01 MPa at 25 deg C. Nevertheless, the electrochemical capacity is extremely low due to the iron corrosion in concentrated KOH. The electrochemical capacities of (Ti{sub 1-x-y} Zr{sub x}M{sub y})Ni compounds for M=V and Si are the most promising in the AB type since a 350 m Ah/g reversible capacity has been measured bY THE CONSTANT POTENTIAL METHOD. We also showed that the partial zirconium substitution made the martensitic transformation temperature higher. (author)

  1. Discussion on Scientific Research to Promote Teaching in Newly-established Application Type Undergraduate Colleges%新建应用性本科院校科研促教学问题探讨

    Institute of Scientific and Technical Information of China (English)

    徐诗举

    2012-01-01

      To pay attention to the application scientific research is demands to realize national goal of undergraduate education, application type undergraduate talent cultivation orientation and serves of local social and economic development. At present, newly-established application type undergraduate colleges must change ideas, create atmosphere of scientific research and the establishment of a sound scientific research to promote teaching mechanism, in order to further improve the quality of application type talents.%  新建应用型本科院校教师必须重视应用性科学研究,这既是实现国家规定的本科生培养目标的需要,也是服务应用型本科人才培养定位和地方社会经济发展的需要。目前,新建应用性本科院校必须在转变思想观念、营造科研氛围和建立健全科研对教学的促进机制等方面下功夫,以求进一步提高应用型人才培养质量。

  2. Controversial identification in a historical case is illustrative of the complexity of DNA typing in forensic research. Response to Charlier et al.

    Science.gov (United States)

    Larmuseau, Maarten H D; Cassiman, Jean-Jacques; Decorte, Ronny

    2014-03-01

    The previously published genetic identification of presumptive samples attributed to two French kings, Henri IV and Louis XVI, by Charlier et al., was recently refuted by a genetic genealogic approach. This (provisional) refutation illustrates the difficulties in confirming the identification of historical DNA samples using limited genetic data. Therefore, we want to stress the necessity of including the genetic genealogic approach--which relies on DNA typing of living relatives of the presumptive donor as a confirmed reference--to validate genetic results in historical cases. Moreover, the popularity and broad media coverage of such studies are useful in bringing awareness to the general public, non-DNA forensic experts and lawyers about the complexity of DNA typing in forensic cases.

  3. Laboratory Research on Fracture-Supported Shielding Temporary Plugging Drill-In Fluid for Fractured and Fracture-Pore Type Reservoirs

    Directory of Open Access Journals (Sweden)

    Dawei Liu

    2017-01-01

    Full Text Available Based on fractures stress sensitivity, this paper experimentally studies fracture-supported shielding temporary plugging drill-in fluid (FSDIF in order to protect fractured and fracture-pore type formation. Experimental results show the FSDIF was better than the CDIF for protecting fractured and fracture-pore type reservoir and the FSDIF temporary plugging rate was above 99%, temporary plugging ring strength was greater than 15 MPa, and return permeability was 91.35% and 120.83% before and after acidizing, respectively. The reasons for the better reservoir protection effect were analyzed. Theoretical and experiment studies conducted indicated that the FSDIF contained acid-soluble and non-acid-soluble temporary shielding agents; non-acid-soluble temporary shielding agents had high hardness and temporary plugging particles size was matched to the formation fracture width and pore throat size.

  4. Chinese medical researches of maternal-fetal ABO blood type incompatibility%母儿ABO血型不合的中医药研究进展

    Institute of Scientific and Technical Information of China (English)

    胡凤英; 赵蕾; 吕玲

    2010-01-01

    母罂ABO血型不合可导致多种新生儿疾病甚至死亡,部分核黄疸幸存儿的智力发育多受到影响.本文综述了母婴ABO血型不合的病因病机、孕前期和妊娠期中医药治疗的方法及其疗效.%Maternal-fetal ABO blood type incompatibility is an autoimmune disease.This disease can lead to miscarriage,stillbirth,children edema,early-onset neonatal jaundice,hemolytic anemia,kemicterus and neonatal death,etc.The author overviewed the etiology and pathogenesis of Matemal-fetal ABO blood type incompatibility,as well as the TCM therapeutic methods and effects in treating this disease at pre-pregnancy period and pregnancy.

  5. Research and Development of Floral Type Congou Black Tea%花香型工夫红茶的开发研究

    Institute of Scientific and Technical Information of China (English)

    黄怀生; 谭正初; 银霞; 粟本文; 郑红发; 赵熙; 梁国强

    2012-01-01

    Preliminary study of variety choice and processing technology was utilized to develop floral type congou black tea. Four varieties and resources of floral type congou black tea were screened as the improved variety from nine hunan local resources and other varieties. Experimental results showed that floral type congou black tea was processed by infrared withering, but the scent had poor durability. Tea materials with one bud two leaves were effectively used to improve qulity of tea products.%为开发花香型工夫红茶,对品种选择和加工工艺进行初步研究。试验从9个湖南地方资源及部分外省品种中筛选出4个适制花香型工夫红茶的茶树品种和单株。在加工过程中,萎凋时用红外灯光照射,制得的工夫红茶带有花香,但花香持久性欠佳;原料选用具有一定成熟度的1芽2叶,有利于产品品质和香气的形成。

  6. Research on Working Process Characteristic of Claw Type Fluid Machinery%爪式流体机械工作过程特性研究

    Institute of Scientific and Technical Information of China (English)

    王君; 刘凯; 姜希彤; 由兆举

    2012-01-01

    A special working process of claw type fluid machinery suction was defined as mixture process, and its working processes, including suction, compression, discharge and mixed process, were analyzed. The changing relation of volume, pressure and temperature varied with shaft rotation angle were investigated, and the rule of resistance moment of claw type rotor in working process was obtained. The study content will help to improve the design and the performance of the claw type fluid machinery.%将爪式流体机械所特有的一个工作过程定义为混合过程,分析了爪式流体机械工作全过程包括吸气、压缩、排气和混合过程的工作特性,讨论了工作过程中容积、压力和温度等状态参数随主轴转角间的变化关系;并得到了爪式转子在工作过程中的所受的阻力矩的变化规律.研究内容有助于爪式转子的型线设计和性能提高.

  7. The research on multi-depot and multi-vehicle-type related vehicle routing problem%类电磁机制算法的应用研究

    Institute of Scientific and Technical Information of China (English)

    段熙鹏; 蔡延光; 汤雅连

    2012-01-01

    The iwproved electromagnetism-like mechanism algorithm (EMA) was introduced, and this algorithm was applied to solve multi-depot and multi-vehicle-type related vehicle routing problem. Local search can improve the ability of fine search in the local area, moreover, mobile coefficient can improve the convergence rate. The results show that improved EMA is feasible and flexible to solve this type of RVRP and its better than traditional EMA.%摘要:针对多车场多车型的关联运输调度问题(Multi-depot and Multi—vehicle—type Related Vehi—cle Routing Problem),对传统的类电磁机制算法进行改进,局部搜索可以提高算法在局部区域精细搜索的能力,并引入了移动系数来提高算法的收敛速度。实验结果证明,改进的算法有效地解决了此类问题且优于传统类电磁机制算法。

  8. Session Types = Intersection Types + Union Types

    CERN Document Server

    Padovani, Luca

    2011-01-01

    We propose a semantically grounded theory of session types which relies on intersection and union types. We argue that intersection and union types are natural candidates for modeling branching points in session types and we show that the resulting theory overcomes some important defects of related behavioral theories. In particular, intersections and unions provide a native solution to the problem of computing joins and meets of session types. Also, the subtyping relation turns out to be a pre-congruence, while this is not always the case in related behavioral theories.

  9. Researcher / Researched: Repositioning Research Paradigms

    Science.gov (United States)

    Meerwald, Agnes May Lin

    2013-01-01

    "Researcher / Researched" calls for a complementary research methodology by proposing autoethnography as both a method and text that crosses the boundaries of conventional and alternative methodologies in higher education. Autoethnography rearticulates the researcher / researched positions by blurring the boundary between them. This…

  10. Facts about Type 2

    Medline Plus

    Full Text Available ... Us in the Fight for a Cure Your tax-deductible gift today can fund critical diabetes research ... Type 2 Diabetes Program Food & Fitness Food Recipes Planning Meals What Can I Eat Weight Loss Fitness ...

  11. Facts about Type 2

    Medline Plus

    Full Text Available ... Funding the Next Generation of Brilliant Researchers Diabetes Pro: Professional Resources Online We Support Your Doctor Clinical ... Type 2 Diabetes Recipes for Healthy Living Diabetes Pro: Professional Resources Shop Diabetes » Close nonprofit software

  12. Advanced industrial technologies by the Tohoku National Industrial Research Institute. ADI function grading by the temperature gradient type austenpering treatment; Tohoku kogyo gijutsu kenkyusho sentan kogyo gijutsu. Ondo kobaigata austenper shori ni yoru ADI keisha kinoka

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1994-10-15

    The advanced industrial technologies were introduced which are under research in the Tohoku National Industrial Research Institute. As for the research to grade the ADI function by the temperature gradient type austempering treatment, an ADI was produced which was graded in both hardness and toughness by austenpering-treating a graphite cast iron sphere. As for the research on the lamination by plating, a composite which was high in lamination strength and low in residual stress was produced by plating the base sheet with a thin film, giving a compressive force and heating it in vacuum in order to produce the composite with ceramics-metal or interceramics lamination. As for the research on the removing method of iron ions from the plating solution, a chelate resin was produced which contained multidentate ligands similar to the nitrirotriacetic acid selectively adsorbing the iron ions. As for the research to evaluate the corrosion of steel in the geothermal water, geothermal hot water in Miyagi Prefecture was experimentally evaluated in damaged quantity of carbon steel and stainless steel. Then, the damaged quantity even of carbon steel was shown to be within the usable limits as a construction structural material. 5 refs., 26 figs., 2 tabs.

  13. Research Curcuma Pieces types of water extracted the most suitable%最适宜煎煮莪术的饮片类型研究

    Institute of Scientific and Technical Information of China (English)

    段伟伟; 李超

    2014-01-01

    目的:探讨能够将莪术有效成分充分煎出的最佳饮片类型。方法:将莪术饮片按厚度分成4mm厚片组、2~3mm细丝组和2mm薄片组,将每组莪术都平均分成三等份,将第一份浸泡0.5 h,将第二份侵泡1 h,将第三份侵泡1.5 h,以水煎法测定这三种莪术饮片的挥发油含量及浸出物含量。结果:2~3mm细丝组莪术饮片的挥发油含量和浸出物含量均明显高于4mm厚片组和2mm薄片组。结论:2~3mm的细丝莪术饮片是最适宜煎煮莪术饮片类型。%Objective: To explore the most suitable water extract of Curcuma Pieces type. METHODS: Curcuma 4mm thick sheet , the sheet of 2mm , 2 ~ 3mm thick filaments of the four groups of the three equal parts , the soaking time was set to 0.5 h, 1 h, 1.5 hours to cook four different types of cooking determination Pieces Curcuma extract content of volatile oil and different immersion time . Results: Volatile oil and extract content of 2 ~ 3mm thick filaments is the highest . Conclusion: Curcuma 2 ~ 3mm thick filaments, is best suited to the type of water extraction Pieces .

  14. Research on timbre modeling technology of sad-type musical instrument.%悲伤型乐器的音色建模技术研究

    Institute of Scientific and Technical Information of China (English)

    尹昊喆; 曹西征; 杜浩翠; 乔锟

    2011-01-01

    提出了一种悲伤型乐器的音色模型,为基于情感的算法作曲提供音响基础.采集擅长表达悲伤情感的乐器的乐音样本,利用离散傅里叶变换获取频谱特征,通过对乐器波形的分析计算获取包络特性,最终构建了一种悲伤型乐器的音色模型.通过实验验证了由该模型产生的悲伤型音色及模型本身具有良好的可调节性.与传统的录制形式相比,该方法成本低,灵活性强,对计算机音乐技术的发展和算法作曲的情感化也起着重要的推动作用.%A kind of timbre model based on sad-type instrument is presented, which can provide the sound basis for emotion-based algorithmic composition. Musical sound samples of the instrument are collected. This instrument is good at expressing sad emotions. And spectral and envelope characteristics are obtained by discrete Fourier transform and analysis calculation method of the instrument waveform. Finally,a kind of timbre model based on sad-type instrument is constructed. Experimental results show the sad-type sound generated by the model and the model itself are well regulated. Compared with the traditional form of recording, this method is of low cost, flexibility, and also plays an important role in promoting the development of computer music technology and the emotional arithmetic composition.

  15. Research on adverse drug events. I. Muscarinic M3 receptor binding affinity could predict the risk of antipsychotics to induce type 2 diabetes.

    Science.gov (United States)

    Silvestre, J S; Prous, J

    2005-06-01

    Antipsychotics are associated with a wide range of adverse effects, several of which may represent a serious health risk to patients. There is an increased concern about metabolic disturbances associated with antipsychotics, including weight gain, dyslipidemia, hyperglycemia, and type 2 diabetes. However, little is known about the mechanisms underlying antipsychotic-induced metabolic disturbances and, in particular, those related to the induction of abnormal glucose metabolism and diabetes. The present article aimed to identify those receptor(s) that are most likely to be involved with or mediate antipsychotics-induced diabetes. Two independent measures taken from literature to indicate the risk of type 2 diabetes associated with 25 typical and atypical antipsychotic drugs were considered, along with their binding affinities to 21 specific receptors (obtained from the resources of Prous Science Integrity). A range of both exploratory and predictive statistical analyses were applied, including principal component factorial analysis, multivariable linear regression analysis, and discriminant analysis. Binding affinities (pKi) to human neurotransmitter receptors and monoaminergic transporters were used as independent variables (predictors). Measures to determine the risk to induce new-onset type 2 diabetes associated with each antipsychotic, logistic regression odds-ratio (dOR) and a discrete scale-based risk (three levels: 'low,' 'moderate,' 'high'), were used as the dependent variables (criteria). Similarly, parallel analyses were also conducted for other measures (average effective therapeutic dose) or adverse effects (weight gain, extrapyramidal side effects, hyperprolactinemia, anticholinergic, hypotension, and sedation) associated with antipsychotics, where underlying mechanisms have been previously established and, therefore, serve as positive-control references. Affinity for the cholinergic muscarinic M3 receptor subtype was presented as the best predictor for

  16. Analysis on the `Thermite` reaction consequences in accidents involving research reactors using plate-type fuel; Analisis sobre las concequencias de la reaccion `Termita` en caso de accidentes en reactores de investigacion que utilizan combustible tipo placa

    Energy Technology Data Exchange (ETDEWEB)

    Boero, Norma L.; Bruno, Hernan R.; Camacho, Esteban F.; Cincotta, Daniel O.; Yorio, Daniel [Comision Nacional de Energia Atomica, San Carlos de Bariloche (Argentina). Centro Atomico Constituyentes

    1999-11-01

    The mixture of Al-U{sub 3} O{sub 8} is not in a state of chemical equilibrium, and at temperatures of between 850 deg C and 1000 deg C, it reacts exo thermally. This is known, in corresponding bibliography as a `Thermite reaction. This mixture is used in the manufacturing of the plate-type fuel used in research reactors. It has been pointed out that the release of energy caused by this type of reactions might represent a risk in case of accidents in this type of reactor. Conclusions, in general, tend to indicate that no such risk exists, although no concrete assurance is given that this is the case, and this fact, therefore, leaves room for doubt. The objective of this paper is to provide an in-depth study of what happens to a fuel plate when it is subjected to thermite reaction. We will, furthermore, analyze the consequences of the release of energy generated by this type of reaction within the core of the reactor, clearly defining the problem for this type of fuel and this kind of reactor. (author) 3 refs., 9 figs., 1 tab.

  17. 汉赛巴尔通体的分子分型研究进展%Progress in molecular typing research for Bartonella henselae

    Institute of Scientific and Technical Information of China (English)

    赵帆; 刘起勇

    2011-01-01

    Bartonella hanselae is an emerging zoonosis pathogen and is world-wide distributed. As the development of molecular biological technology, several molecular typing methods have been applied in the epidemiological investigation of the pathogen, which facilitates the understanding of the diversity and phylogenic relation among B. Henselae isolates. This paper summarizes the applications of several molecular typing methods in the molecular epidemiological investigation of B. Henselae.%汉赛巴尔通体是一种新发的人兽共患病病原,呈全球性分布.随着分子生物学技术的发展,多种分子分型方法应用于其流行病学调查,加深了研究者们对汉赛巴尔通体种内变异和系统发育关系的了解.本文就几种常见的分子分型方法在汉赛巴尔通体分子流行病学研究中的应用做一综述.

  18. AEG评审在型号合格审定中的研究与应用%Research and Application of AEG Evaluation on Type Certification

    Institute of Scientific and Technical Information of China (English)

    段本印

    2015-01-01

    概述了申请人的航空器评审工作,并简要对比分析了运行符合性清单、型别等级和训练要求、MMEL、MRBR、OCAI等11个AEG工作评审项目。同时通过对比分析航空器评审组(简称AEG)评审与型号合格审定之间的区别和联系,为申请人顺利开展AEG工作提出4条建议。%The applicant’ s work of aircraft evaluation is introduced in this paper, and 11 aircraft evaluation items are listed, including operation compliance checklist, type rating and qualification specification, MMEL, MRBR, OCAI, etc. The difference and relation between aircraft evaluation and type certification are contrasted and ana-lyzed at the same time ,and 4 suggestions are provided to the applicant in order to develop aircraft evaluation.

  19. 交接配线式ODN结构的研究%Research on Cross-Connecting Distribution Line Type of ODN Structure

    Institute of Scientific and Technical Information of China (English)

    沈敬忠

    2012-01-01

    In order to solve the problem in choosing wining structure of building the FTTH (Fiber To The Home)network under the uncertain conditions of access users,we use qualitative and quantitative analysis methods to compare cross-connecting distribution line type of ODN (Optical Distribution Network) structure and direct connecting distribution line type of ODN structure,find out that it has a stable access ability and a wide covering ability and a flexible expansion ability,so that is appropriate for the application in the competitive telecommunication market,has certain reference significance during large-scale construction projects on the FTTH network.%针对光纤到户(FTTH:Fiber To The Home)网络建设中,在接人用户不确定条件下的配线结构选择问题,通过定性和定量的分析方法,对直接配线式ODN(Optical Distribution Network)结构与交接配线式ODN结构进行比较.结果表明,交接配线式ODN结构具有接入稳定、覆盖范围大和扩容灵活的优点,适宜在竞争的电信市场环境中应用,对FTTH的大规模工程建设具有一定的借鉴意义.

  20. Application Research of Clamp Type Robot Hand Material%夹钳式机器人手部材料应用探析

    Institute of Scientific and Technical Information of China (English)

    张立军; 赵永瑞; 相恒富

    2012-01-01

    The robot's hand is the most important actuating mechanism, and its material has an important influence on the use of the whole robot. The key points in the design of robot hand were analyzed and the needful properties of material of robot hand were proposed. Based on these, two important parameters of σ/p and E/p were proposed, and commonly used material and some new type material for robot hand and their performance were studied in detail, and the contrasts of the material performance were carried out. It was pointed out that new type material of high strength Light damping is the development direction of robot hand material.%机器人的手部是最重要的执行机构,其材料选用恰当与否,对机器人的使用效果有很大影响.分析机器人手部的设计要点,给出手部材料应具备的性能.在此基础上,提出优选材料的两个重要参数:比强度和比刚度.详细研究目前机器人手部材料及其性能,并对其特性进行对比分析.指出新型高强度轻质阻尼材料是今后机器人手部材料的发展方向.

  1. 2型糖尿病的运动治疗机制研究进展%The Research Progress of Exercise Therapeutic Mechanisms of Type 2 Diabetes

    Institute of Scientific and Technical Information of China (English)

    徐国琴; 陈建才; 林文弢

    2012-01-01

    Using the literature review method, this paper reviews the pathogenesis of type 2 diabetes and exercise therapeutic mechanisms. The study results have shown that the disorders of glucose and lipid metabolism, oxidative stress, low-grade in- flammation and endoplasmic reticulum stress are related with the development of type 2 diabetes. Exercise can improve glucose and lipid metabolism status, insulin resistance, endocrine disorder status, inflammatory status, oxidative stress and endoplasmic reticulum stressqnduced factors to treat diabetes.%应用文献资料法对2型糖尿病的发病机制和运动治疗机制进行综述,研究表明糖脂代谢紊乱、氧化应激、低度炎症和内质网应激均与2型糖尿病的发生发展有关。运动可通过改善糖脂代谢状态、外周组织胰岛素抵抗、内分泌紊乱状态、炎症状态、氧化应激状态和内质网应激相关诱发因子等途径治疗糖尿病。

  2. 4类昆虫信息化学物质在不同缓释载体上的释放速率%Researches on the Release Rates of Four Types of Insect Semiochemicals from Four Dispenser Types

    Institute of Scientific and Technical Information of China (English)

    李学琳; 孔祥波; 张苏芳; 王鸿斌; 张真; 杨茂发

    2015-01-01

    放量,然后释放速率逐渐下降到低释放状态。在释放高峰期,2种成分的释放速率只有第43天差异不显著,其余时间段均差异显著。【结论】明确了昆虫信息化学物质在4种常用缓释载体上的释放模式及其诱芯在林间的释放动态特征,对评价仿生诱芯在害虫种群监测和防控中的使用效果具有指导意义,可为生产上针对不同信息化学物质选用最适宜的缓释载体提供技术支持。%[Objective]In order to develop effective lures that can uniformly and persistently release biologically active semiochemicals in the field,it is necessary to determine the release rates of various insect pheromones and host volatiles from different types of commonly used dispensers after the active compounds are identified. [Method]In this study,the release rates of four common bark beetle aggregation pheromone components ( ipsenol,ipsdienol,trans-verbenol and S-cis-verbenol),two major Dendrolimus sex pheromone components (Z5,E7-12:Ald and Z5,E7-12:OH),and two conifer host volatiles ( S-( - )-α-pinene and R-( + )-α-pinene ) from four different types of dispensers were investigated under laboratory conditions ( temperature,24 -26 ℃; relative humidity,50%-80%; wind speed,300 mL·min -1 ) using dynamic headspace volatile collection method. The entrapped components on Porapak Q were extracted from sampling tubes with hexane and quantified by Gas Chromatography. [Results]Results indicated that ipsenol had higher release rates than ipsdienol from the polyvinylchloride bubble cap dispensers over the test period,showing significant differences for both ( +) and ( -) enantiomers of ipsenol and ipsdienol on day 2 ,22 ,and 29 . Ipsenol and ipsdienol released quickly in the first two days and gradually declined to the lower release level on day 15 ,then increased sharply during days 15 -36 with a peak of release rates at the day 36,but finally declined to a consistent low release level. The

  3. Research and Application of FTA and Petri Nets in Fault Diagnosis in the Pantograph-Type Current Collector on CRH EMU Trains

    Directory of Open Access Journals (Sweden)

    Long-long Song

    2015-01-01

    Full Text Available A fault tree is established based on structural analysis, working principle analysis, and failure mode and effects analysis (FMEA of the pantograph-type current collector on the Chinese Rail High-Speed Electric Multiple Unit (CRH EMU train. To avoid the deficiencies of fault tree analysis (FTA, Petri nets modelling is used to address the problem of data explosion and carry out dynamic diagnosis. Relational matrix analysis is used to solve the minimal cut set equation of the fault tree. Based on the established state equation of the Petri nets, initial tokens and enable-transfer algorithms are used to express the fault transfer process mathematically and improve the efficiency of fault diagnosis inferences. Finally, using a practical fault diagnosis example for the pantographs on CRH EMU trains, the proposed method is proved to be reasonable and effective.

  4. 曼尼希碱环氧树脂固化剂的研究进展%Research development of Mannich base type epoxy resin curing agents

    Institute of Scientific and Technical Information of China (English)

    宋道理

    2011-01-01

    The synthesis principles and methods,the development history and tendency of Mannich base type epoxy resin curing agents were introduced in this paper.The technique of improving toughness and heat resistance, reducing viscosity of curing agents were descr%阐述了曼尼希碱型环氧树脂固化剂的合成原理、合成方法和发展历史与发展趋势,并就增加固化剂韧性、耐热性、降低固化剂黏度和开发水下固化剂以及改进固化剂生产工艺等方面进行了探讨。

  5. 苯丙胺类兴奋剂滥用的治疗研究进展%Progress of therapeutic research for amphetamine-type stimulants abuse

    Institute of Scientific and Technical Information of China (English)

    江海峰; 赵敏; 孙海明; 王石斌; Walter Ling

    2008-01-01

    苯丙胺类物质是一组具有类似化学结构的中枢神经系统兴奋剂,包括苯丙胺(amphetamine)、甲基苯丙胺(methamphetamine,MA,俗称冰毒)、亚甲基二氧基甲基苯丙胺(MDMA,俗称摇头丸)等其他苯丙胺类精神兴奋剂。上世纪90年代以来,苯丙胺类中枢兴奋剂(amphetamine—type stimuants,ATS)滥用增长势头迅猛,超过海洛因、可卡因等传统非法精神活性物质,呈全球蔓延之势,

  6. 姜黄素防治2型糖尿病的研究进展%Research Progress of Preventing Type 2 Diabetes by Curcumin

    Institute of Scientific and Technical Information of China (English)

    陈培; 张玉领

    2011-01-01

    姜黄素是从姜黄中提取的一种多酚类物质,具有抗癌,抗炎,抗氧化等多种生物学作用,最近研究发现姜黄素具有明显降低糖尿病大鼠血糖、血脂,明显改善2型糖尿病大鼠糖代谢,脂代谢紊乱的症状.%Curcumin is a kind of polyphenols extracted from turmeric, and has many biological effects, such as anti-canccr, anti-inllammatory,antioxidant and so on. The recent studies have found that curcumin could significantly reduce blood glucose and blood lipids of diabetic rats, and significantly improve the symptoms of glucose metabolism and lipid metabolism disorders in type 2 diabetic rats.

  7. 热消散式流量传感器的建模仿真与研究%Simulation and research of heat-dissipation type flow sensor

    Institute of Scientific and Technical Information of China (English)

    田丰; 高振斌; 孙以材

    2011-01-01

    根据能量守恒定律和流量测量原理,使用流体计算软件建立了热消散式流量传感器的数学模型并进行了数值分析.模拟了管内传感器与流体的湍流换热过程,计算出在不同流速下的传感器探头温度分布情况,分析了流体温度、传感器封装材料、加热功率以及安装方式对传感器测量精度和适用量程的影响.计算结果对热式流量传感器的设计和优化提供了重要的参考依据.%According to the conservation law of energy and the principle of flow rate measurement, the numerical simulation of heat-dissipation type flow sensor was established by Fluent software in this paper. The process of turbulent heat transfer between sensor and fluid in the flow pipe was simulated, and the temperature distribution of the sensor was investigated under conditions of various flow velocities. The influences of the fluid temperature, package material of sensor, heating power and installation way on measurement accuracy and measurement range were analyzed. The present results could provide reference for design and optimization of thermal type flow sensor.

  8. Research on and Design of a Self-Propelled Nozzle for the Tree-Type Drilling Technique in Underground Coal Mines

    Directory of Open Access Journals (Sweden)

    Yiyu Lu

    2015-12-01

    Full Text Available Due to the increasing depths of coal mines and the low permeability of some coal seams, conventional methods of gas drainage in underground mines are facing many problems. To improve gas extraction, a new technique using water jets to drill tree-type boreholes in coal seams is proposed. A self-propelled water-jet drilling nozzle was designed to drill these boreholes. The configuration of the self-propelled nozzle was optimized by conducting drilling experiments and self-propelling force measurements. Experimental results show that the optimal self-propelled nozzle has a forward orifice axial angle at 25°, a radial angle at 90°, a center distance of 1.5 mm, and backward pointing orifices with an axial angle of 25°. The self-propelling force generated by the jets of the nozzle with 30 MPa pump pressure can reach 29.8 N, enough to pull the hose and the nozzle forward without any external forces. The nozzle can drill at speeds up to 41.5 m/h with pump pressures at 30 MPa. The radial angles of the forward orifices improve the rock breaking performance of the nozzle and, with the correct angle, the rock breaking area of the orifices overlap to produce a connecting hole. The diameter of boreholes drilled by this nozzle can reach 35.2 mm. The nozzle design can be used as the basis for designing other self-propelled nozzles. The drilling experiments demonstrate the feasibility of using the tree-type drilling technique in underground mines.

  9. 端塞式反向器的优化设计与研究%Optimal Design and Research of End Plug Type Reverser

    Institute of Scientific and Technical Information of China (English)

    樊伟; 郝大贤; 李晓; 王科社; 查初亮

    2015-01-01

    反向器的优劣直接影响到滚珠丝杠副的使用性能,而回珠曲线是影响滚珠丝杠副性能的关键因素。文中通过对反向器进行力学分析,得出一种新型的滚珠丝杠副反向器的回珠曲线,并对此设计曲线在ADAMS中进行仿真分析,对比分析优化前后端塞式滚珠丝杠副反向器的运动情况,结果表明优化后的多段圆弧式反向器与滚珠的碰撞力明显减小,大大提高了滚珠丝杠副反向器的流畅性。%Reversers quality directly affects the performance of ball screw pair ,and the ball curve is the key factors that affect the performance of ball screw pair. This article analyzes the mechanics of the reverser and obtains a new type of ball curve of the ball screw pair of reverser. The simulation of the design curve is carried out using ADAMS to compare movement situation of end plug type ball screw pair of reverser before and after optimization, the results show that the optimized multistage arc reverser and ball collision force decreased greatly, the ball screw pair of reverser fluency is greatly improved.

  10. Research on closed-loop supply chain network equilibrium with two-type suppliers, risk-averse manufacturers and capacity constraints

    Directory of Open Access Journals (Sweden)

    Hao Sun

    2015-04-01

    Full Text Available Purpose: the aim of this paper is to investigate the closed-loop supply chain (CLSC network equilibrium wiht the consideration of three practical factors: two complementary types of suppliers, risk-averse character of the manufacturer and capacity constraints of the suppliers. Design/methodology/approach: The equilibrium of various decision makers including the suppliers, the manufacturers, the retailers, the collectors and the demand markets are modeled via finite-dimensional variational inequality, respectively. Then the governing CLSC network equilibrium model is established. The logarithmic-quadratic proximal prediction-correction algorithm is designed to solve the variational inequality model. Numerical examples are given to analyze the impact of return rate, risk-averse degree and capacity constraints on the network equilibrium under different product BOMs. Findings: with the increase of return rate, the profits of various channel members and the performance of the CLSC system will improve. There is a contradiction between profit maximization and risk minimization for the manufacturers. Moreover, the economic behavior of the CLSC is likely to be limited by the capacity constraints of the suppliers. Originality/value: Prior to this paper, few papers have addressed with the CLSC network equilibrium considering some practical factors. They assume all the suppliers are identical and all the decision-makers are risk neutral. Furthermore, the production capacities of all suppliers are assumed to be infinite or large enough. To fill the gap, this paper examines the influences of two-type suppliers, risk aversion and capacity constraints upon the CLSC network equilibrium.

  11. Assessing the TP53 marker type in patients treated with or without neoadjuvant chemotherapy for resectable colorectal liver metastases: a p53 Research Group study.

    Science.gov (United States)

    Pilat, N; Grünberger, T; Längle, F; Mittlböck, M; Perisanidis, B; Kappel, S; Wolf, B; Starlinger, P; Kührer, I; Mühlbacher, F; Kandioler, D

    2015-05-01

    The type of a biomarker - whether it is prognostic or predictive - is frequently not known, although such information is crucial for assessing the clinical value of a marker. In order to evaluate the type of marker TP53 is, we identified a cohort of 76 patients with colorectal liver metastases (CLM), homogeneously staged as resectable, who had been treated either with or without fluorouracil-based neoadjuvant chemotherapy. The TP53 genotype was assessed retrospectively from paraffin-embedded, diagnostic tumour biopsies using a standardised, p53 gene-specific sequencing protocol (mark53(®) kit). The overall median survival was 44.2 months, and the overall TP53 mutation frequency was 55%. A significant interaction was observed between chemotherapy and TP53 status (P = 0.045). To illustrate this effect, the 51 patients with and the 25 patients without neoadjuvant chemotherapy were described separately. In patients with neoadjuvant chemotherapy, mutated TP53 was significantly associated with poor survival (P = 0.0025), resulting in five-year survival rates of 22%, compared to 60% in patients with normal TP53. The hazard ratio was 3.12 (95% confidence intervals (CI): 1.46-6.95) to the disadvantage of TP53-mutated patients and 5.49 (P = 0.0001; 95% CI: 2.28-13.24) after adjustment for known prognostic factors. In patients treated with surgery alone, a mutated TP53 did not have a negative effect on survival (P = 0.54). A mutated TP53 status independently predicted survival disadvantage in CLM patients in the presence, but not in the absence, of neoadjuvant chemotherapy. Our data suggest that TP53 might be a pure predictive marker.

  12. [Research on modeling method to analyze Lonicerae Japonicae Flos extraction process with online MEMS-NIR based on two types of error detection theory].

    Science.gov (United States)

    Du, Chen-Zhao; Wu, Zhi-Sheng; Zhao, Na; Zhou, Zheng; Shi, Xin-Yuan; Qiao, Yan-Jiang

    2016-10-01

    To establish a rapid quantitative analysis method for online monitoring of chlorogenic acid in aqueous solution of Lonicera Japonica Flos extraction by using micro-electromechanical near infrared spectroscopy (MEMS-NIR). High performance liquid chromatography(HPLC) was used as reference method.Kennard-Stone (K-S) algorithm was used to divide sample sets, and partial least square(PLS) regression was adopted to establish the multivariate analysis model between the HPLC analysis contents and NIR spectra. The synergy interval partial least squares (SiPLS) was used to selected modeling waveband to establish PLS models. RPD was used to evaluate the prediction performance of the models. MDLs was calculated based on two types of error detection theory, on-line analytical modeling approach of Lonicera Japonica Flos extraction process was expressed scientifically by MDL. The result shows that the model established by multiplicative scatter correction(MSC) was the best, with the root mean square with cross validation(RMSECV), root mean square error of correction(RMSEC) and root mean square error of prediction(RMSEP) of chlorogenic acid as 1.707, 1.489, 2.362, respectively, the determination coefficient of the calibration model was 0.998 5, and the determination coefficient of the prediction was 0.988 1.The value of RPD is 9.468.The MDL (0.042 15 g•L⁻¹) selected by SiPLS is less than the original,which demonstrated that SiPLS was beneficial to improve the prediction performance of the model. In this study, a more accurate expression of the prediction performance of the model from the two types of error detection theory, to further illustrate MEMS-NIR spectroscopy can be used for on-line monitoring of Lonicera Japonica Flos extraction process. Copyright© by the Chinese Pharmaceutical Association.

  13. 茶文化资源类型及业态范式研究%Research on the Type and Mode of the Development of Tea Culture Resource

    Institute of Scientific and Technical Information of China (English)

    沈学政; 苏祝成; 王旭烽

    2015-01-01

    中华茶文化通过与农业融合反哺地方经济,形成茶文化产业。本文采用文化资源基础理论,将茶文化资源分为五大主要类型,并进一步细分为15种基本类别和13种茶文化产业类型。随后以福建省、武夷地区、大益品牌为案例,分别从一个省、一个地区、一个企业的角度总结茶文化资源3种产业开发范式,即比较优势模式、点轴开发模式和产业延伸模式,探讨茶文化资源综合开发对于区域经济和茶业转型升级的意义。%Chinese tea culture converged the local economy and agriculture to form the tea cultural industry. Based on the theory of cultural resource, this thesis divided the tea culture heritage resources into 5 major types. And further more, we subdivided it into 15 basic categories. Meanwhile, in view of the different types of tea cultural heritage resources, we put forward 13 main development mode, which promote the regional economy and advance the tea industry transformation and upgrading. Then, taking Fujian Province, Wuyi area, TAETEA as the case, respectively, we summed up 3 kinds of development mode of tea cultural heritage resource, from a province, a region, a business point of view, namely comparative advantage model, point a xis development model and the extended model industry.

  14. 不同类型葡萄膜炎患者致病原因分析%Etiology research on different types of uveitis

    Institute of Scientific and Technical Information of China (English)

    杨喆; 相义会; 付颖

    2016-01-01

    目的:分析不同类型葡萄膜炎患者的致病原因。  方法:选取2012-06/2015-06在我院进行诊治的葡萄膜炎患者60例120眼,所有患者均由同一葡萄膜炎专科医生,按照统一诊疗规范进行检查。依据国际葡萄膜炎研究定制的标准,将其分为:前葡萄膜炎、中葡萄膜炎、后葡萄膜炎、全葡萄膜炎。观察患者的年龄、性别、葡萄膜炎类型及患病原因。  结果:通过对患者的病因及临床类型分析,所选葡萄膜炎患者主要特发性26眼(21.7%)、VKH 综合征18眼(15.0%)、HLA-B27相关性14眼(11.7%)、病毒性12眼(10.0%)、Fuchs 综合征8眼(6.7%)、Behcet 病8眼(6.7%)、糖尿病6眼(5.0%)、梅毒6眼(5.0%)、青光眼睫状体综合症6眼(5.0%)、幼年型慢性关节炎4眼(3.3%)、交感性眼炎4眼(3.3%)、外伤性2眼(1.7%)、类肉瘤2眼(1.7%)、眼内炎2眼(1.7%)、其他2眼(1.7%);通过对不同葡萄膜炎的病因观察,前葡萄膜炎病因主要有特发性病例,其次是HLA-B27相关性、病毒性;全葡萄膜炎的治病原因中以VKH综合征、特发性病例和Behcet病为主;后葡萄膜炎主要是特发性病例,其次是病毒性感染;中间葡萄膜炎以特发性病例为主。  结论:通过对临床患者观察分析,葡萄膜炎患者男性多于女性;特发性、VKH 综合征、病毒性伴发的葡萄膜炎和Behcet病是其常见的葡萄膜炎类型。%AlM:To analysis and discuss etiology of different types of uveitis. METHODS:We selected 60 patients ( 120 eyes ) with uveitis treated in our hospital from June 2012 to June 2015. All patients examined by the same uveitis specialist with unified standards. According to international standards, uveitis was customized into:anterior uveitis ( AU) , intermediate uveitis ( lU) , posterior uveitis ( PU) , panuveitis ( PanU ) . Age, gender, type of uveitis and causes of the disease were analyzed. RESULTS:Through the analysis of the

  15. Preprint of the results of `the publicly applied proposal type and hi-tech (emphasized) field research and development in fiscal 1995`; `1995 nendo teian kobogata saisentan (juten) bun`ya kenkyu kaihatsu` seika hokokukai yokoshu

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1997-02-01

    The preprint was prepared of a report meeting for the results of `the publicly applied proposal type and hi-tech (emphasized) field research and development in fiscal 1995` to be held in Tokyo during February 12 to 14, 1997. In the meeting, a lecture titled `The system of fundamental researches and its execution` is to be given as a special lecture and the following are as general lectures: `Energy/environmental technology and next generation catalysts,` ` The present and outlook of surgery in the 21st century - computer surgery,` The present situation of education and research related to the design of digital integrated systems,` and `The present and future of research and development of a new carbon material, fullerene.` Research reports were prepared by field as follows: 73 papers in the new material technology field, 46 in the bio-technology field, 36 in the electronics/information technology field, 8 in the mechanical system technology field, 8 in the human life engineering technology field, 23 in the medical/welfare equipment technology field, 5 in the resource technology field, 17 in the energy/environment technology field.

  16. 胃转流手术治疗2型糖尿病机制的研究进展%Advanced in mechanism research about the gastric bypass operation for the treatment of type 2 diabetes mellitus

    Institute of Scientific and Technical Information of China (English)

    侯亚勃; 高寅生; 杨晓军; 高鹏

    2014-01-01

    胃转流手术治疗2型糖尿病的疗效已经得到明确的肯定,但其确切的治疗机制尚不清楚,目前,临床认为可能是由于术后胃肠道正常解剖结构的改变,引起与血糖代谢有关的胃肠道激素的变化,使糖尿病病情得到缓解,本文就近年来有关胃转流手术治疗2型糖尿病的机制研究作一综述.%It has been confirmed clearly that gastric bypass operation could be used for tbe treatment of type 2 diabetes mellitus.However,the curative mechanism underlying this therapy remain unclear up to now.Referencing the curative mechanisms research progress from domestic and abroad,the possible mechanism is considered as the secretion of gastrointestinal hormones can be changed after gastric by~ss operation,which has altered the normal anatomy structure of the gastrointestinal,and so as to the situation of type 2 diabetes mellitus can be controlled.This review will summarize recent papers related to mechanism research about the gastric bypass operatiou for the treatment of type 2 diabetes mellitus.

  17. 湿式独立自排导垂直发射技术研究%Research on the Wet-type Concentric Canister Launcher

    Institute of Scientific and Technical Information of China (English)

    马艳丽; 姜毅; 王伟臣; 刘伯伟; 颜凤

    2011-01-01

    To study the overhigh pressure in the canister during the wet-type canister missile vertical launching, the wet-type concentric canister launchers of various structure parameters are calculated numerically. The launching process of the concentric canister with 17mm space between the inside and outside and single-canister are analyzed numerically with the dynamic update method. Considering the effect of water vaporization, the flow field of vapor and liquid is resolved by Mixture model of dual-phase flow. The zone moving and dynamic laying method was adopted in the meshes update. The result indicates that the smaller space between the inside and outside or the distance between nozzle and rear cover, the bigger pressure in the canister, and the guiding cone in the bottom can obviously decrease the pressure on the rear cover. Therefore, the calculation result accords with the experiment well.%湿式独立自排导垂直发射技术在发射过程中可能会存在发射筒内压力过高的问题,就不同结构参数的湿式独立自排导垂直发射装置进行数值计算,并采用动网格对内外筒间距为17 mm及单筒发射的导弹发射过程进行数值研究和分析.计算中考虑水的汽化效应,采用Mixture两相流计算模型求解气液两相流场,网格更新方法采用域动分层法.结果表明,内外筒间距越小,燃气的排导越受限制,筒内的压力越大;喷管出口与后盖部的距离越小,筒内压力越大;底部加导流锥对于降低后盖上的压力作用明显,计算结果与试验符合较好.

  18. Comparative Research on Z-Type Tower and Traditional T-Type Tower for UHVDC Transmission Lines Located at Mountain Areas%特高压直流输电山区线路Z型杆塔与T型杆塔的比较

    Institute of Scientific and Technical Information of China (English)

    万亦如; 陈稼苗; 周浩; 张彤; 苏菲; 沈志恒; 陆海清

    2012-01-01

    UHVDC transmission lines in China have to pass through a lot of mountainous regions where lightning strokes frequently occur, thus the shielding failure outage rate of UHVDC transmission line adopting conventional T-type towers and passing through mountainous region is high. For this reason, a new type of tower possessing a new type of tower head, namely the Z-type tower, is designed for the part of UHVDC transmission line from Xiluodu to Zhexi, which passes through mountainous regions. The lightning withstand performances of back flashover and shielding failure of T-type tower and Z-type tower as well as their impacting factors are researched by the simulation in which the calculation model of shielding failure is established by electrical geometry model (EGM) and the calculation model of back flashover is established by ATP-EMTP, meanwhile combining CDEGS software with formula method the electromagnetic environment of Z-type tower is assessed. Research results show that the Z-type tower's lightning withstand performances of back flashover is high, therefore the overall lightning withstand performance of Z-type tower is evidently better than that of T-type tower. Under the lowest nominal height of tower, the electromagnetic environment parameters of Z-type tower can reach national environmental standards and are better than those ofT-type tower. Thus it can be seen that the Z-type tower is more suitable to be applied in mountainous regions than T-type tower.%我国特高压直流输电工程途经大量山地,雷电活动频繁,而常规T型塔在山区的绕击跳闸率较高,为此针对溪洛渡一浙西特高压直流输电山区线路设计了一种新型杆塔fz型塔)。针对Z型塔,对比T型塔,采用改进电气几何模型与ATP.EMTP软件,计算分析了反击、绕击耐雷性能及其影响因素,同时采用CDEGS软件结合公式法对z型塔的电磁环境做了评估。结果表明:Z型塔的反击耐雷水平很高,

  19. Research Progress of Floating Gate Type Organic Nonvolatile Memories%浮栅型有机非易失性存储器的研究

    Institute of Scientific and Technical Information of China (English)

    陆旭兵; 邵亚云; 刘俊明

    2013-01-01

    有机柔性电子器件具有低制造成本、大面积、可柔性折叠等优点,是近年来国内外学术界和工业界的研究热点。有机非易失存储器是一种重要的有机柔性电子器件。介绍了浮栅型有机非易失性存储器件的工作原理;综述了国内外学术界对浮栅型有机非易失性存储器的研究进展、存在的问题及解决对策。%The organic electron devices have been widely investigated in both academia and industry due to their advantages of low cost , large area , and flexibility etc .The organic nonvolatile memory is one of the important or-ganic devices .In this paper , we will first explain the working principles of the floating gate type organic nonvolatile memory.Then we will introduce some recent progresses of the floating gate organic nonvolatile memories .Finally the existing challenges and possible solutions for their low voltage , high reliability operations were discussed .

  20. Research progresses on cryptoexplosion breccias type gold deposits%隐爆角砾岩型金矿床的研究进展

    Institute of Scientific and Technical Information of China (English)

    毛光武; 严卸平; 舒文辉; 祖俊龙; 王波涛; 白昌华

    2016-01-01

    The article summarizes the progress on concept definition,metallogenic tectonic geological conditions,and features,metallogenetic fluid characteristics and cryptoexplosive breccia diagenetic and metallogenetic mechanism of cryptoexplosive breccia and the breccia type gold deposits.Such deposit is prolific in the ancient land activation area,Mesozoic fault basin edge or island arc volcanic belt of the Pa-cific Rim.The ore body is spatially and temporally related closely to hypabyssal-ultra shallow acidic por-phyry bodies and occurs at top of the body which are alkali-rich and silicon-rich and belongs to "I" type granite.When pressure of the high heat energy thermal fluid at top of the body is greater than the sum of the tensile strength of the surrounding rock and the minimum principal stress cryptoexplosion occur and the cryptoexplosive breccia is formed.Commonly the cryptoexplosive breccia cylinder is vertically zoned as crack phase 、shattered phase、blasting phase、channel phase.Breccia size tends horizontally to be smaller from center to edge.The Instant burst of ore-forming fluid in a closed system creates a semi-open or open system and leads to relative large pressure gradient.Pressure of the ore-forming fluid is reduced and the fluid boiled.Mixture,immiscibity of the fluid and water-rock reaction change the physiochemical condi-tion and cause reduction of solubility of gold complexes and the complexes precipitate to be gold minerali-zation.Formation of cryptoexplosive breccia cylinder and evolution of thermal fluid were promoted and o-verprinted sequentially upward from the bottom in the process of “temperature increase-(explosion)boil-temperature decrease-temperature increase-(explosion)-boil-temperature decrease”.“boil-temperature de-crease”is the main ore material precipitation stage.This type of gold deposit is characterized by metallo-genic series and system.Multi-type ores occur in one intrusive body or one cylinder.It is significant to

  1. Research on the construction of learning type Party branch of students%学习型学生党支部建设研究

    Institute of Scientific and Technical Information of China (English)

    官桂香

    2012-01-01

      This paper introduces the learning typeof students' Party branch, and conducts the correlation analysis on the characteristics, and then combines with the actual point to point out and summarize the approach to construct the learning type Party branch of students, aims to strengthen the building of students' Party branch, better maintain and improve the advanced status and leadership skills of grass-roots Party organizations among students.%  本文对学习型学生党支部的概况进行了介绍,并对其特点进行了相关分析,进而结合实际指出并归纳了构建学习型学生党支部的途径,目的在于切实加强学生党支部的建设,更好地保持和提高基层党组织在学生中的先进性地位和领导能力

  2. 一种新型光伏微型逆变器系统的研究%Research on a New Type of Photovoltaic Micro-Inverter System

    Institute of Scientific and Technical Information of China (English)

    车福来; 张晓光

    2013-01-01

    This paper designed a new type of photovoltaic micro-inverter system, giving the hardware structure and software design. The main control section adopted the redundant structure, being able to switch to the spare chip’s running at the time of the failure of main chip. The testing result of 225 W experiment prototype shows that the system has stable control performance, high efficiency, simple circuit and low cost with application value of engineering.%  设计了一种新型光伏微型逆变器系统,给出了硬件结构及软件设计,主控制部分采用冗余结构,在主芯片出现故障时,可切换到备用芯片运行。对225 W实验样机的测试结果表明,该系统控制性能稳定,效率较高且电路简单,成本较低,具有工程应用价值。

  3. 个性化医疗服务类型及相关数据资源研究%Service Types and Data Resources Research on Personalized Medicine

    Institute of Scientific and Technical Information of China (English)

    刘宁; 武琼; 陈敏

    2016-01-01

    Personalized medicine can chooses the best treatment programs for patients with individual differences. It could effectively reduce health care costs and improves resource utilization. On the basis of the introduction of personalized medicine concepts, this paper analyzes the types of personalized healthcare services and related data resources that support personalized medicine, such as genetic data, electronic medical records, health records and health monitoring information. At the same time, proposes counter measures and suggestions to its launch.%个性化医疗可针对患者个体差异选择并提供最佳诊疗方案,能有效提升医疗服务质量,降低医疗费用。文章在介绍个性化医疗相关概念的基础上,分析了个性化医疗的服务类型及支撑个性化医疗的相关数据资源,如基因数据、电子病历、健康档案及健康监测信息等,并对实现信息资源整合,促进个性化医疗服务的开展,提出了相关对策和建议。

  4. 心理学中两种话语分析方法研究%Research on Two Types of Discourse Analysis Approaches ;in Psychology

    Institute of Scientific and Technical Information of China (English)

    陈玉娟

    2015-01-01

    心理学中两种话语分析方法主要是指:批判性话语分析和非批判性话语分析。批判性话语分析更多关注自我、身份认同、权力关系以及社会变化等主题。非批判性话语分析则主要研究人们运用话语建构心理现实的方式,话语对于说话人的影响等。本文针对批判性话语分析和非批判性话语分析两种研究方法进行了比较。%The two types of discourse analysis approaches in psy-chology are mainly critical discourse analysis and non-critical discourse analysis. Critical discourse analysis concerns more with such themes as self, identity, power relationship and social changes. Non-critical discourse analysis mainly studies people's styles of using discourses to construct psychological reality and the influences of discourses on people. This paper makes a com-parison between critical discourse analysis and non-critical dis-course analysis.

  5. Type-indexed data types

    OpenAIRE

    Hinze, R.; Jeuring, J.T.; Löh, A.

    2004-01-01

    A polytypic function is a function that can be instantiated on many data types to obtain data type specific functionality. Examples of polytypic functions are the functions that can be derived in Haskell, such as show, read, and ‘==’.More advanced examples are functions for digital searching, pattern matching, unification, rewriting, and structure editing. For each of these problems, we not only have to define polytypic functionality, but also a type-indexed data type: a data type that is con...

  6. H型高血压与心脑血管疾病关系的研究进展%Research progress of H type hypertension and disease of heart head blood-vessel

    Institute of Scientific and Technical Information of China (English)

    谭志辉

    2015-01-01

    High blood pressure accompany increased homocysteine (Hcy) or H type hypertension is very common in clinic. High blood pressure and high homocysteine (HHcy) coexistence can promote a significantly increased risk of disease of heart head blood-vessel. In this paper, Hcy metabolism, causes of increased Hcy, H type hypertension and disease of heart head blood-vessel treatment HHcy, research progress are reviewed.%高血压伴同型半胱氨酸(Hcy)增高即H型高血压在临床上很常见,高血压与高Hcy(HHcy)共存时可使心脑血管疾病的风险显著增加。本研究对Hcy代谢、引起Hcy增多的因素、H型高血压与心脑血管疾病关系及HHcy治疗的研究进展进行综述。

  7. 填充型树脂基导热绝缘复合材料的研究及应用进展%Research and Application Progress of Filled-type Resin-based Thermal Conductive Insulating Composites

    Institute of Scientific and Technical Information of China (English)

    张新娜; 刘成莉; 李娟; 谢瑚

    2015-01-01

    The research situation of filled-type resin-based thermal conductive insulating composites was reviewed, and their preparation method and application situation in motor and packaging field were introduced. The main influence factors of thermal conductivity for filled-type resin-based thermal conduc-tive insulating composites were summarized.%综述了填充型树脂基导热绝缘复合材料的研究现状,介绍了该材料的制备方法及其在电机及封装等领域的应用情况,总结了影响填充型树脂基导热绝缘复合材料导热性能的主要因素,并展望了高导热绝缘复合材料的发展方向。

  8. Interactions between Child Types and Classroom Types.

    Science.gov (United States)

    Solomon, Daniel; Kendall, Arthur J.

    Research is described which explores the hypothesis that different classroom situations may be optimal for different individuals. The approach used cluster analysis to identify student and classroom "types" whose interactions were then examined in an analysis of variance framework. About 1,300 fourth graders from 50 classrooms were involved in the…

  9. African primary care research: Participatory action research

    Directory of Open Access Journals (Sweden)

    Bob Mash

    2014-01-01

    Full Text Available This article is part of the series on African primary care research and focuses on participatory action research. The article gives an overview of the emancipatory-critical research paradigm, the key characteristics and different types of participatory action research. Following this it describes in detail the methodological issues involved in professional participatory action research and running a cooperative inquiry group. The article is intended to help students with writing their research proposal.

  10. Stories on Research, Research on Stories

    Science.gov (United States)

    Petit, Sandrine; Mougenot, Catherine; Fleury, Philippe

    2011-01-01

    This article deals with a group of researchers involved in Participatory Action Research projects on biodiversity and who volunteered to take part in a "storytelling" experiment. Their "stories" were used to describe this new type of research collective comprising various partners, including researchers and managers, focused on obtaining directly…

  11. 芒硝型卤水石灰—烟道气法净化工艺实验研究%Experimental Research on Na2SO4 Type Brine with Lime-Flue Gas Purification Mehtod

    Institute of Scientific and Technical Information of China (English)

    周国敏; 谢兴胜; 陈留平

    2013-01-01

    在试验室中对不同浓度硫酸根的芒硝型卤水石灰—烟道气法净化工艺中石灰的添加量与卤水中硫酸根的浓度进行研究,利用图上作业的办法,找出两者之间的关系.%Using Na2SO4 Type brine with different concentration sulface ion in the labratory, the relations between quantity of added lime and concentration of sulfate ion in the brine was researched by drawing diagram with lime - flue gas purification method.

  12. 新型高校智库发展研究%Research on the development of a new type of university think tank

    Institute of Scientific and Technical Information of China (English)

    林秀芬

    2016-01-01

    The think tank is an important feature of soft power. In recent years, with the rapid development of think tanks, University think tanks, which are based on development-oriented research and consulting local government decision-making have also been established. Review the background of the development process of University think tanks, focuses on the effectiveness, collaborative management and the development orientation of university think tanks, we want to find the ways to improve development of the new University think tanks.%智库是国家软实力的重要特征,近年来,随着我国智库的迅速发展,面向地方经济社会发展和政府决策咨询研究为主的高校智库也纷纷建立。回顾我国高校智库的发展历程及新型高校智库建设的背景,着重探讨当前高校智库发展所面临的效力发挥不足、协同管理不足、发展定位不清晰等困境,并结合上述困境提出建设新型高校智库发展的路径探索。

  13. Research of New-typed Anti-halitosis Chewing Gum%新型除口臭口香糖的研制

    Institute of Scientific and Technical Information of China (English)

    张金威; 李胡俊; 周鸿媛; 侯大军

    2011-01-01

    本文对新型除口臭口香糖的配方和加工工艺进行了研究;在传统口香糖配方和加工工艺的基础上,对新型除口臭口香糖的工艺进行了研究.通过试验确定出新型除口臭口香糖的最佳配方为:金银花用量为3.00mL/10g,锌含量2.00mg/10g,茶多酚用量为0.06g/10g;辅料吸收的最适温度为60℃.%In this paper, the formulation and processing technology of anti-halitosis functional chewing gum were studied.Based on the traditional chewing gum formulation and processing technology, the removing bad breath technics of antihalitosis functional chewing gum was researched as well. According the tests, the best compound is: 3.00mL/10g honeysuckle, 2.00mg/10g zinc, 0.06g/10g tea polyphenols and 60 ℃ for materials absorbing.

  14. Ames Research Center cryogenic mirror testing program - A comparison of the cryogenic performance of metal and glass mirrors with different types of mounts

    Science.gov (United States)

    Miller, Jacob H.; Melugin, Ramsey K.; Augason, Gordon C.; Howard, Steven D.; Pryor, G. Mark

    1989-01-01

    A summary of the cryogenic testing of glass and metal mirrors performed at NASA Ames Research Center (ARC) and two other places is presented. Recent improvements to the ARC Cryogenic Optics Test Facility are described. The purposes of the tests were to determine: (1) how glass mirrors would perform at cryogenic temperatures compared with metal mirrors and (2) how various mirror mounts would affect the cryogenic performance of mirrors. Details of a cryogenic test of a 50 cm 'double arch', fused-silica mirror with a three-point mount and with a radially-compliant, flexured mount are given. Within the accuracy of the measurements, it was determined that the flexured mount did not induce appreciable distortion in the double arch mirror. Results of the cryogenic tests of a number of glass mirrors and two beryllium mirrors are included. The cryogenic distortion of the glass mirrors was found to be less than that for the beryllium mirrors. Within the accuracy of the measurements, no hysteresis was found in the glass mirrors. It was possible to measure hysteresis in one of the beryllium mirrors.

  15. Ab Initio Research on a New Type of Half-Metallic Double Perovskites, A2CrMO6 (A = IVA Group Elements; M = Mo, Re and W

    Directory of Open Access Journals (Sweden)

    Yun-Ping Liu

    2014-03-01

    Full Text Available The research based on density functional theory was carried out using generalized gradient approximation (GGA for full-structural optimization and the addition of the correlation effect (GGA + U (Coulomb parameter in a double perovskite structure, A2BB’O6. According to the similar valance electrons between IIA(s2 and IVA(p2, IVA group elements instead of alkaline-earth elements settled on the A-site ion position with fixed BB' combinations as CrM (M = Mo, Re and W. The ferrimagnetic half-metallic (HM-FiM properties can be attributed to the p-d hybridization between the Crd-Mp and the double exchange. All the compounds can be half-metallic (HM materials, except Si2CrMoO6, Ge2CrMo and Ge2CrReO6, because the strong-correlation correction should be considered. For M = W, only A = Sn and Pb are possible candidates as HM materials. Nevertheless, an examination of the structural stability is needed, because Si, Ge, Sn and Pb are quite different from Sr. All compounds are stable, except for the Si-based double perovskite structure.

  16. Reshaping technology research of landscape type Taxus chinensis var. mairei%观赏型南方红豆杉重塑技术研究

    Institute of Scientific and Technical Information of China (English)

    欧建德; 张卫明; 周东雄; 潘军; 王金盾

    2012-01-01

      The reshaping trial of Landscape type Taxus chinensis var. mairei was conducted in Fujian Mingxi. The results show that the stem cutting-off can promote ground diameter growth of Taxus chinensis,inhibit plant height and high growth. The shorter length of remain stem, the smaller the plant height and high growth. The stem cutting-off can not affect the plant canopy, but shrink shear strength can significantly inhibit crown growth. The stem cutting-off can promote latent buds germination of Taxus chinensis, and longer remained stem got more buds. The stem cutting-off can promote the new branches germination; the shorter remained stem and high strength shrink shear could increase the number of new branches germination. The stem cutting-off had no significant effect on upright, flat new branches differentiation. However, shorter length of remain stem and high shear strength can significantly increase the proportion of upright new branches, reduce the proportion of the flat type of new branches. The stem cutting-off or not, the remaining stem height and shrink shear strength have no significant effect on leaf color. The stem cutting-off can increase the leaves and branches. Shorter remaining stem and high strength shear can further promote the dense of leaves and branches.%  在福建省明溪县进行观赏型南方红豆杉重塑技术试验。结果表明:截干能够促进南方红豆杉地径生长,能够抑制植株高度及高生长,留干长度越短、缩剪程度越重其植株高度及高生长越小。截干不能影响植株冠幅,但缩剪强度能够显著抑制冠幅生长。截干可以促进南方红豆杉干上潜伏芽的萌发,且留干较长的萌蘖数量较多。截干能够促进新枝萌发,且留干较短且强度缩剪对新枝萌发数量有促进作用。截干对直立型、平展型新枝分化无明显影响,但留干长度较短且强度缩剪可以显著增加直立型新枝比例,减少平展型新枝比例

  17. Blood Types

    Science.gov (United States)

    ... blood, safe blood transfusions depend on careful blood typing and cross-matching. The ABO Blood Group System ... that provided by the ABO positive/negative blood typing. For example, sometimes if the donor and recipient ...

  18. Blood typing

    Science.gov (United States)

    A blood sample is needed. The test to determine your blood group is called ABO typing. Your blood sample is mixed with antibodies against type A and B blood. Then, the sample is checked to see whether ...

  19. Research on Vibration and Noise of JS315 - type Reducer%JS315型减速机振动噪声的研究

    Institute of Scientific and Technical Information of China (English)

    王伟; 张亚琴

    2012-01-01

    齿轮箱的振动和噪声能够反映齿轮装置的品质,影响齿轮箱振动和噪声的因素有齿轮啮合、轴系变形、箱体精度以及安装误差等因素,其中齿轮啮合是主要因素,而齿轮的基节偏差和齿形偏差又是影响齿轮传动平稳性的主要因素.通过对公司JS315型减速机振动和噪声的研究,分析了影响齿轮箱振动和噪声的因素,找出了造成振动和异响的原因,成功解决了这一问题.%The vibration and noise of gearbox can reflect the quality of gear device, influence factors of gear box vibration and noise have the gearing mesh, shaft deformation, the gear case accuracy, installation error and so on, among which the gearing mesh is the major factor. The main factors which influence the stability of gear is gear base pitch deviation and the tooth profile deviation. Through the vibration and noise JS315 - type reducer, the influence factors of gear vibration and noise are analyzed,and the causes of abnormal sound and vibration are found out. The problem is successfully solved.

  20. 新型燃气燃烧器的数值模拟研究%Numerical Simulation Research of New Type Gas Burner

    Institute of Scientific and Technical Information of China (English)

    胡远庆; 蒋利桥; 呼和涛力; 杨卫斌; 赵黛青

    2013-01-01

    采用数值模拟方法对自行设计的可调自吸式烟气再循环燃气燃烧器的燃烧性能进行了研究,探讨了预燃室和引射器喉部结构尺寸参数对燃烧器燃烧特性的影响.结果表明:预燃室尺寸参数对烟气的自循环量影响作用显著,当预燃室过大或者过小时,均不利于烟气自循环;引射器喉部尺寸适当地增大,有利于增加自循环的烟气量;随着自循环烟气量增大,火焰温度峰值位置前移,火焰长度变短.%The numerical simulation method was used to investigate the combustion characteristics of a new type gas burner with adjustable self-sucked flue gas recirculation(FGR),and the influences of the size of premix chamber and ejector throat on combustion characteristics were analyzed.The results show that the premix chamber size had an important influence on flue gas recirculation(FGR).While the premix chamber too big or too small,it was unfavorable for FGR.Larger throat diameter of ejector contributed to more amount of recirculation flue gas.And with increasing the amount of recirculation flue gas,the peak flame temperature position moved forward and the flame length got shortened.

  1. Differences between Mice and Humans in Regulation and the Molecular Network of Collagen, Type III, Alpha-1 at the Gene Expression Level: Obstacles that Translational Research Must Overcome

    Directory of Open Access Journals (Sweden)

    Lishi Wang

    2015-07-01

    Full Text Available Collagen, type III, alpha-1 (COL3A1 is essential for normal collagen I fibrillogenesis in many organs. There are differences in phenotypes of mutations in the COL3A1 gene in humans and mutations in mice. In order to investigate whether the regulation and gene network of COL3A1 is the same in healthy populations of mice and humans, we compared the quantitative trait loci (QTL that regulate the expression level of COL3A1 and the gene network of COL3A1 pathways between humans and mice using whole genome expression profiles. Our results showed that, for the regulation of expression of Col3a1 in mice, an eQTL on chromosome (Chr 12 regulates the expression of Col3a1. However, expression of genes in the syntenic region on human Chr 7 has no association with the expression level of COL3A1. For the gene network comparison, we identified 44 top genes whose expression levels are strongly associated with that of Col3a1 in mice. We next identified 41 genes strongly associated with the expression level of COL3A1 in humans. There are a few but significant differences in the COL3A1 gene network between humans and mice. Several genes showed opposite association with expression of COL3A1. These genes are known to play important roles in development and function of the extracellular matrix of the lung. Difference in the molecular pathway of key genes in the COL3A1 gene network in humans and mice suggest caution should be used in extrapolating results from models of human lung diseases in mice to clinical lung diseases in humans. These differences may influence the efficacy of drugs in humans whose development employed mouse models.

  2. Test Research on Beneficiation of Calcite Type Fluorite Ore in Hu'nan%湖南某方解石型萤石选矿试验研究

    Institute of Scientific and Technical Information of China (English)

    胡瑞彪; 吉红; 陈典助; 荆正强

    2013-01-01

    The CaF 2 grade of calcite type fluorite ore from Hu'nan is reaching up to 56 .72%,regard as high-grades fluorite ore .According to the mineralogical characteristic of the ore ,the fluorite was studied,Using sodium carbonate as pH adjusting agent ,sodium silicate and starch as depressant ,so-dium oleate as collector , closed -circuit test were carried out in the condition that the roughing grinding fineness was -0 .074 mm 65%.The grade and recovery of the fluorite concentrate were 97.16%and 80.38%respectively,and the content of SiO2 and CaCO3 meet the national standards . The results showed that concentrate were obtained by swept one rougher -five cleaners-one scav-enging and coarse concentrate regrinding closed -circuit process .%湖南某方解石型萤石矿原矿含CaF256.72%,属高品位萤石矿。结合该矿石的工艺矿物学特性,采用碳酸钠为pH调整剂、水玻璃+淀粉为抑制剂、油酸钠为捕收剂进行浮选试验研究。闭路试验在粗选磨矿细度-0.074 mm占65%的情况下,通过一粗五精一扫-粗精矿再磨的工艺流程,可以获得品位97.16%、回收率80.38%的萤石精矿,且萤石精矿中含SiO21.20%、CaCO30.65%,达到国家萤石粉F97C的质量标准。

  3. Research of the relationship of pedestrian injury to collision speed, car-type, impact location and pedestrian sizes using human FE model (THUMS Version 4).

    Science.gov (United States)

    Watanabe, Ryosuke; Katsuhara, Tadasuke; Miyazaki, Hiroshi; Kitagawa, Yuichi; Yasuki, Tsuyoshi

    2012-10-01

    Injuries in car to pedestrian collisions are affected by various factors such as the vehicle body type, pedestrian body size and impact location as well as the collision speed. This study aimed to investigate the influence of such factors taking a Finite Element (FE) approach. A total of 72 collision cases were simulated using three different vehicle FE models (Sedan, SUV, Mini-Van), three different pedestrian FE models (AM50, AF05, AM95), assuming two different impact locations (center and the corner of the bumper) and at four different collision speeds (20, 30, 40 and 50 km/h). The impact kinematics and the responses of the pedestrian model were validated against those in the literature prior to the simulations. The relationship between the collision speed and the predicted occurrence of head and chest injuries was examined for each case, analyzing the impact kinematics of the pedestrian against the vehicle body and resultant loading to the head and the chest. Strain based indicators were used in the simulation model to estimate skeletal injury (bony fracture) and soft tissue (brain and internal organs) injury. The study results primarily showed that the injury risk became higher with the collision speed, but was also affected by the combination of the factors such as the pedestrian size and the impact location. The study also discussed the injury patterns and trends with respect to the factors examined. In all of the simulated conditions, the model did not predict any severe injury at a collision speed of 20 km/h.

  4. Literature Research on Scraping Therapy for Each Type of Cervical Spondylosis%刮痧疗法治疗各型颈椎病的文献研究

    Institute of Scientific and Technical Information of China (English)

    李文文; 孟繁洁; 靳英辉; 周倩妹

    2014-01-01

    目的:分析刮痧疗法在治疗各型颈椎病中的应用现状。方法:在国内知名的信息检索网站上,按照预定的文献纳入标准和信息提取方案,收集和整理国内有关刮痧治疗颈椎病的随机对照试验类文章,并根据文献调研结果进行分析。结果:刮痧治疗颈椎病有较好疗效,无明显不良反应,安全可靠,经济便捷。结论:刮痧疗法治疗颈椎病有较好疗效,值得临床推广应用。%Objective:To analyze the application status of scraping therapy in each type of cervical spondylosis. Methods:According to the predeter-mined literature inclusion criteria and information extraction scheme, collected domestic articles of randomized controlled trial that about treating cer-vical spondylosis by scraping therapy on the domestic famous information search website and arranged them, and analyzed the literature according to the investigation result. Results:Scraping therapy has good curative effect on cervical spondylosis and no severe adverse reactions, which is safe and reliable, economical and convenient. Conclusion:Scraping therapy has good curative effect on cervical spondylosis, deserves clinical promotion and application.

  5. 复合交联型深部调驱体系应用研究%Application Research of Type Composite Crosslinking Deep Displacement System

    Institute of Scientific and Technical Information of China (English)

    杨军

    2014-01-01

    以安达奥瑞特石油装备有限责任公司生产的复合交联型深部调驱剂作为主要药剂。采用布氏粘度计检测流变性、物理模拟实验以及矿产实验等方法,从温度、矿化度、抗剪切性以及矿场施工等方面对复合交联型深部调驱剂进行评价测定。室内实验表明:使用复合交联型深部调驱剂配制而成的深部调驱液对温度、矿化度的影响不大,抗剪切能力强,突破压力达到1.7Mpa时,堵塞率达90%以上。%To anda Mr.Rhett oil equipment co., LTD.Production of composite crosslinking deep oil displace-ment agent as the main agents.y brookfield viscometer testing rheological property, Physical simulation experi-ment and the experimental methods such as minerals, From the temperature, salinity, shear resistance and field construction of composite crosslinking deep to evaluate oil displacement agent determination .aboratory experi-ments show that Use type composite crosslinking deep oil displacement agent preparation and deep displacement of little influence on temperature and salinity, Shear resistance is strong, the breakthrough pressure of 1.7 Mpa, the plugging rate was over 90%.

  6. 基于Kinect的轴类零件三维重建研究%Research on Kinect-based 3 D Reconstruction of Shaft-type Parts

    Institute of Scientific and Technical Information of China (English)

    王亚琪; 陈成军; 李希彬; 李全宝

    2015-01-01

    This paper analyzed and improved 3D reconstruction algorithm of axis parts using the depth information from KinectTM.Firstly,RGB-D data was captured by Kinect and the depth information was converted into 3D point cloud with actual model by using coordinate transformation;Secondly,the target obj ect of interest point cloud data were extracted.Ac-cording to the noise characteristics of point cloud data,a fast bilateral filtering was used to the data perform denoising opera-tion;Besides,an improved point cloud segmentation algorithm was proposed to acquire the point cloud database.Finally, the parameterization scheme for the structure of the point cloud database was analyzed precisely.The results show that the proposed algorithm has much better performance in the reconstruction of shaft-type parts and efficiency.%使用Kinect采集的深度数据,进行了轴类零件三维重建算法的研究。首先借助 Kinect获取深度和彩色数据,通过坐标转换将深度信息转换成三维点云数据;其次提取出感兴趣目标的点云数据,根据点云数据的噪声特点,并对其进行滤波降噪处理;然后进行点云分割获得点云集,最后对各点云集进行结构参数化分析。实验结果表明,本文算法能够精确、高效地实现轴类零件的重建。

  7. Laboratory Research of the New Integrative Gel Type Resin System%新型一体化树脂固砂液体系的室内研究

    Institute of Scientific and Technical Information of China (English)

    曹砚锋; 李蔚萍; 李玉光; 林科雄; 王珊; 舒福昌; 向兴金

    2014-01-01

    Because sand flowed seriously in the process of the development of unconsolidated sand reservoir,sand control technique became one of the main measures to maintain the long-term normal production of the well in such reservoir. Laboratory preliminary developed the new integrative gel type resin system in order to improve the curing strength of sand body in view of the sand control of sandy well in unconsolidated sand heavy reservoir at sea. Such system can meet the sand consolidation work of oil field which showed many advantages in the laboratory study such as good performance of cementation solidifying,high permeability retention after borehole enlargement,strong consolidation at low temperature,consolidation of good quality,intense corrosion resistance and so on.%疏松砂岩油藏开发过程中出砂严重,防砂技术成为维持疏松砂岩油藏油井长期正常生产的主要措施之一。针对海上疏松砂岩稠油油藏开采出砂井防砂问题,室内初步研制了新型一体化树脂固砂液体系以提高砂体胶结强度。室内研究表明,新型一体化固砂液体系具有良好的胶结固化性能,扩孔后渗透率保留率高,低温固结性能强,固结质量好,抗腐蚀性能强,能够满足油田现场的固砂作业。

  8. 营销移动作业新型校验仪的研制%Research on New Type Calibration Instrument for Marketing Mobile Operation

    Institute of Scientific and Technical Information of China (English)

    邱星; 霍政界; 王立白

    2016-01-01

    The fieldtestof traditional electricity metersrelied on artificial analysis and record of fielddata,which iseasy tocause data error due to human factors and unable to realize standardization of calibration. A new type calibrationinstrument for marketing mobile operation could realizeautomatic recognition of wiring mode and calibration methods of electricitymeter standardized operation. It establishes multiple data intelligent diagnostic model based on information such as current cutoff, loss of phase,voltage-loss and severe three-phase unbalance. The model can automatically identify and diagnose abnormal power consumption behavior like electricitytheft by analyzing and comparing with the user data of power user electric energy data acquisition system.It also establishes a model for distinguishing the abnormal operationstate of electricitymeter,which can realize automatic distinction of abnormal operationstate of electricity meter.%对传统电能表的现场检测主要依赖人工进行现场数据分析和录入,易造成人为因素错误,无法实现检测工作标准化。营销移动作业新型校验仪可实现电能表接线方式和检测方式的自动识别,建立以断流、断相、失压、三相严重不平衡等信息为基础的多数据智能诊断模型,并通过与用户采集系统的用电信息进行分析和比对,自动识别诊断疑似窃电等用电异常行为;同时建立基于多数据关联技术的电能表运行异常判别模型,实现电能表运行异常自动甄别。

  9. Research on Types and Distribution Regions of Global Serious Emergencies%全球重大突发事件规律研究

    Institute of Scientific and Technical Information of China (English)

    张霞; 薛耀文

    2015-01-01

    根据 EM-DAT 数据库对1900-2013年全球范围内13445例重大突发事件的发生类型、发生总量、死亡人数及区域分布等方面进行了描述性统计分析,通过分析得出:全球重大突发事件主要发生类型为自然灾害,自然灾害呈现递减趋势,事故灾难和社会安全类事件表现出增加趋势;亚洲是事件发生总量及死亡人数最多的地区;在各区域中自然灾害和事故灾难类事件占有最高比重;除个别年份外各地区的重大突发事件死亡率基本相同;非洲和亚洲的亿元 GDP 死亡率较高,大约为其他地区的10倍左右。%According to the analysis of the types,total number,death toll and regional distribution of the seri-ous emergencies around the world based on the EM-DAT from 1900 -2013,it gets that natural disasters account for highest proportion and show decline tendency,otherwise the number of technical disasters and social security in-creases;Asia has suffered more occurrence and fatalities than other regions,and emergencies is led by natural and technical disasters in every region;serious emergencies death rate is nearly equal in every region;death rate per hundred million GDP in Africa and Asia is almost 10 times than other regions.

  10. Research on Different TCM Syndrome Types of Reflux Esophagitis and Helicobacter Pylori Infection%反流性食管炎不同中医证型幽门螺杆菌感染的研究

    Institute of Scientific and Technical Information of China (English)

    叶蔚; 姚嘉明; 刘彬彬; 刘庆生; 王小奇

    2013-01-01

    目的:研究反流性食管炎不同中医证型与幽门螺杆菌感染的关系.方法:对960例反流性食管炎患者的进行中医分型,分为肝胃郁热、脾胃虚弱、气郁痰阻3型.检测和分析反流性食管炎患者的不同内镜分级的幽门螺杆菌感染率,以及不同中医证型反流性食管炎与幽门螺杆菌感染的关系.结果:中重度反流性食管炎的感染率明显高于轻度的患者.不同中医证型的反流性食管炎的Hp感染率存在着明显的差异,而且气郁痰阻证>肝胃郁热证>脾胃虚弱证.结论:不同中医证型反流性食管炎与幽门螺杆菌感染存在明显的关系.%Objective: Research on the relationship between different TCM syndrome types of reflux esophagitis and He-licobacter pylori infection was made. Methods:960 patients with reflux esophagitis were divided into three TCM syndrome types: the type of liver and stomach heat retention, the type of stomach and spleen weakness and the type of Qi depression and phlegm resistance. The Helicobacter pylori infection rate of reflux esophagitis patients under gastroscope grading and the relationship between TCM syndrome type of reflux esophagitis and Helicobacter pylori infection were analyzed. Results : The Helicobacter pylori infection rate of the moderate and severe reflux esophagitis patients was higher than that of the slight ones. There were significant differences of the Helicobacter pylori infection rate with three TCM syndrome types. Conclusion:The relationship between different TCM syndrome types of reflux esophagitis and Helicobacter pylori infection is significant.

  11. A Research on the Comparison of the MultipleIntelligince Types of the Candidates Who Succeeded and Failedinthe Entrance Exams of Physical Educationand Sports School

    Directory of Open Access Journals (Sweden)

    Murat KUL

    2014-07-01

    Full Text Available The purpose of the study , candidates who participated in a special aptitude test of Physical Education and Sports School are compared those who were eligible to register with the win of Multiple Inte lligence Areas. In the research Scan model was used. Within the investigation, in 785 candidates who applied Bartin Universty School of Physical Education and Sports Special Ability Test for 2013 - 2014 academic year, 536 volunteer candidates who have average age x yaş = 21.15± 2.66 constitude. As data collection tool, belogns to the candidates personal information form and “Multiple Intelligences Inventory” which was developed by Özden (2003 for he identification of multiple intellegences was applied. Reliability coefficient was discovered as .96. In evaluation of data, SPSS data an alysis program was used. In evaluation of data, frequency, average, standard, deviation from descriptive statistical techniques was used. Also by taking into account normal distribution of the data, Independent Sample T - test of statistical techniques was u sed. In considering the findings of the study “Bodily - Kinesthetic Intelligence” which is a field of Multiple Intelligences of candidates as statistically significant diffirence was found in the area. Candidates winning higher than avarage scores candidates who can not win are seen to have. Also, “Social - Interpersonal Intelligence” of candidates qualifing to register with who can not qualify to register statistically significant results were observed in the levels. Winning candidates in this area compared t o the candidates who win more than others, it is concluded that they carry the dominant features. As a result of “Verbal - Linguistic Intelligence”, “Logical - Mathematical Intelligence”, “Musical - Rhythmic Intelligence”, “Bodily - Kinesthetic Intelligence, “Soci al - Interpersonal Intelligence” of Multiple Intelligence Areas candidates who participated in Physical Education

  12. Contrasting total carbon and nitrogen stocks between ecological site types in a Sub-Boreal research forest in central British Columbia

    Energy Technology Data Exchange (ETDEWEB)

    Bois, C.H.; Janzen, D.T. [Northern British Columbia Univ., Prince George, BC (Canada). Ecosystem Science and Management Program; Sanborn, P.T.; Fredeen, A.L. [Northern British Columbia Univ., Prince George, BC (Canada). Ecosystem Science and Management Program]|[Northern British Columbia Univ., Prince George, BC (Canada). Natural Resources and Environmental Studies Inst.

    2006-07-01

    Carbon (C) sequestration and carbon stocks within managed and natural forests have become topical issues since the adoption of the Kyoto Protocol. A multi-year study was conducted to evaluate the total C stocks present in a 10 km{sup 2} area of University of British Columbia's Aleza Lake Research Forest located 60 km east of Prince George in the Sub-Boreal Spruce biogeoclimatic zone of east-central British Columbia. The purpose was to address gaps in knowledge about forest C budgets, total pool sizes, dynamics of forest floor and mineral soil carbon by studying the effects of forest management. Sampling plots were chosen randomly within strata composed of the dominant ecological site classes, soil textures and management histories. The study involved the creation of 137 plots, of which 108 and 29 were located on fine and coarse textured soils, respectively. Sampling was reduced in these strata due to a shortage of middle-aged stands and the near lack of coarse textured soils. Data collection and sampling methodology were adapted from the National Forest Inventory Ground Sampling Guidelines of the Canadian Forest Service. Carbon stocks were measured in forest floor and mineral soil to a depth of 1 metre. The Dumas-combustion method was used to determine C and nitrogen (N) concentrations. It was determined that stand age did not decidedly change the forest floor or mineral soil total C and N in either fine or coarse textured soil plots. However, forest floor C and N were considerably higher in coarse textured soils compared to C and N measured in fine soil plots. Mineral soil C concentration decreased methodically with depth from 4.6 per cent C at 0 cm to 0.2 per cent at 100 cm. The paper also addressed the breakdown of forest floor and mineral soil C and N pools according to ecological site series.

  13. The research of copper enrichment in four types of shellfish%4种海洋贝类对海水中铜(Cu)的富集能力

    Institute of Scientific and Technical Information of China (English)

    郭远明; 刘琴; 顾捷; 尤炬炬; 孙秀梅; 刘士忠

    2012-01-01

    为研究4种海洋贝类(泥蚶、菲律宾蛤仔、缢蛏、单齿螺)对海水中铜(Cu)的富集效应.设置Cu浓度分别为0.0l5、0.020、0.025、0.035、0.065和0.ll5mg/L 6个试验组,采用半静水法进行泥蚶、菲律宾蛤仔、缢蛏、单齿螺对海水中Cu的富集试验,分别在0、l、3、5、l0、15、20、25、30d取出部分贝类用微波消解一原子吸收光谱法测定Cu含量.结果表明:4种贝类均对Cu表现出了一定的富集效应,单壳类对Cu的富集效应明显大于双壳类.水体中Cu浓度达到0.035mg/L时,泥蚶和单齿螺对Cu的富集效应明显.水体中Cu浓度达到0.025mg/L时,菲律宾蛤仔和缢蛏对Cu富集明显.贝类体内Cu含量总体上随水体中Cu含量增加而增加,但当水体中Cu浓度在某个浓度点时,贝类体内的Cu含量反而有个低点.这一低点对于泥蚶为0.025mg/L、对于菲律宾蛤仔和单齿螺为0.035mg/L,缢蛏并不明显.贝类体内Cu含量总体上随富集时间的增加而增加.在3~5d时,贝类体内Cu含量明显降低,在5~10d后Cu含量又继续增加.同时,实验还进一步探讨了贝类对重金属的富集机制,比较了不同贝类对重金的富集能力.%The copper enrichment effects in four types of shellfish including Tegillarca granosa, Ruditapes philippinarum, Sinonovacula constricat canarck and Monodonta labio were studied in this paper. The study was carried out through the static test method. The shellfish was cultivated in seawater contaminated with different copper concentrations (0.015, 0.02, 0.025, 0.035, 0.065 and 0.115 mg/L, respectively). The content of Cu was analyzed in muscle tissue using atomic absorption spectrometry with microwave digestion in 0, 1, 3, 5, 10, 15, 20, 25 and 30 d, respectively. The results indicated that the four types of shellfish had copper enrichment effect. The concentration of copper in monoplacophora was higher than that in bivalvia. The copper content in T. granosa and M. labio exhibited

  14. 两种新型油冷却器传热性能对比实验研究%Two Kinds of New Type of High-efficiency Oil Cooler Heat Transfer Performance Contrast Experimental Research

    Institute of Scientific and Technical Information of China (English)

    梁建活; 江楠; 曾纪成

    2014-01-01

    The experimental validation is used to study the heat transfer performance of two kinds of high-efficiency oil cooler.A fin tube type oil cooler with aluminum fin tubes supported by segmental baffles and an oil cooler with spiral tubes supported by helical baffles are explored in the research respectively.The test results show that the fin tube type oil cooler get a better com-prehensive performance.The heat flow rate of fin tube type oil cooler is larger and the pressure drop through the shell pass is smaller than the values of the helical baffle oil cooler under the same condition of low to moderate oil flow rate.The heat transfer capacity of unit pressure drop in the fin tube type oil cooler is 1 .5 times as that of the helical baffle oil cooler.Furthermore,the compact structure of the fin tube type oil cooler is good enough to meet the development trend of miniaturization equipment and high efficiency.%对采用铝翅片扩展表面与弓形折流板支撑结构相结合的新型叠片式油冷却器和采用螺纹强化管的螺旋折流板油冷却器分别进行实验测试研究。结果表明,叠片式油冷却器具有更优良的综合性能;在中、小油流量时,其热交换量大、壳程压降较小,单位压降下的换热量要比螺旋折流板油冷却器约高50%,结构的紧凑性能够较好地满足设备小型及高效的发展趋势。

  15. Research on Bone Metabolism of Elderly Patients with Type 2 Diabetes Combined with Hip Fracture%2型糖尿病并髋部骨折高龄患者骨代谢研究

    Institute of Scientific and Technical Information of China (English)

    范秀丽

    2016-01-01

    Objective To discuss the changes of bone metabolism of elderly patients with type 2 diabetes combined with hip fracture and understand its mechanism thus further discussing and analyzing the correlation between type 2 diabetes and hip fracture. Methods The group A (elderly patients with type 2 diabetes combined with hip fracture), group B (patients with simple type 2 diabetes) and group C (healthy persons) were selected as the research objects with 78 cases in each, the parathyroid hormone, bone gla-containing protein, calcitonin and bone mineral density of the three groups were measured and compared. Results The differences in the various indexes of bone metabolism and bone mineral density between the el-derly patients with type 2 diabetes combined with hip fracture and the patients with simple diabetes were not obvious with-out statistical significance(P>0.05), however, the BGP, CT and BMD of the two were lower than those of healthy persons(P0.05),但二者与健康者比较,BGP、CT、BMD均较低(P<0.05),PTH则较高(P<0.05)。结论高龄2型糖尿病患者非常容易出现骨质疏松症,骨吸收有所增加但骨形成降低,高龄2型糖尿病患者的骨质量改变与髋部骨折无直接关系。

  16. 一部集中我国研究型医院理论和实践结合发展研究成果的专著%A monograph focus on research the development theory and practice in China researching-type hospital

    Institute of Scientific and Technical Information of China (English)

    王明晓

    2016-01-01

    Some of researching type hospital have been built since 2004 when the concept of researching type hospital was presented by QIN Yinhe, the president of general hospital of PLA. To communication the results of the development theory and practice in China researching-type hospital, a monograph named research type hospital management focused on theory and practice of research type hospital development has been compiled by QIN Yinhe and his team since 2013. The chapters of this monograph involves pandect, plan, leadership, research, human resources, transformation, teaching, nursing, quality, service, ideal, security, logistic, medical ethic, culture and safety and it is the newest and richest monograph which can reflect the general quality of hospital management.%自2004年解放军总医院原院长秦银河教授提出创建研究型医院以来,该理论不断得以丰富深化。以解放军总医院为代表,国内涌现了一批研究型医院。为了集中反映国内研究型医院理论和实践结合的研究成果,2013年开始,由秦银河教授担任主编,集中全国数百名医院管理专家,利用两年的时间,编撰出版了《研究型医院管理学》。该书分为总论、谋划、领导、科研、学科、人才、转化、教学、护理、质量、服务、信念、保障、后勤、医德、文化和安全等18个章节,是目前反映国内医院管理整体水平的一部专著。

  17. Research on New Type Refrigeration Device Based on Thermoelectric Effect%基于热电效应的新型制冷器件研究

    Institute of Scientific and Technical Information of China (English)

    祝薇; 陈新; 祝志祥; 朱承治; 韩钰; 马光; 邓元

    2015-01-01

    This paper firstly introduces the principle of thermoelectric cooler. Based on Peltier effect, when the current passes through the thermoelectric leg, the carriers in the material will bring heat and move from one side to the other side, which would lead to the phenomenon of cooling. Thermoelectric cooler has many advantages, such as no noise, no pollution, cooling rapidly, simple operation, strong reliability and accurate temperature control. With the miniaturization development of power electronics and higher demand of sensitivity for infrared detection, it is required to fabricate smaller and better thermoelectric cooler. Thus, the study of miniaturization of thermoelectric cooler has attracted many attentions in recent years. Then the paper describes the applications of thermoelectric cooler in the fields of power electronics, military, space exploration, commercial and scientific research. Thermoelectric cooler can realize the temperature control for power electronic devices, instruments and so on. At last, the key problems of thermoelectric cooler and the development directions are summarized, which provides an idea for the further study of thermoelectric cooler.%介绍了热电制冷的基本原理,基于热电材料的帕尔贴效应,电流通过驱动热电材料中的载流子运动并携带热量实现制冷,具有无噪声、无污染、制冷迅速、操作简单、可靠性强、易于实现高精度温控等优点.随着大功率电子器件微小化集成化发展以及红外探测灵敏性要求的提高,对热电制冷在体积上和性能上又提出了新的要求.热电制冷器的微型化成为近年来的研究热点,概括了热电制冷在电力电子、军事、空间探测、商业和科研等技术领域的应用,其支撑了电力器件、电子元件以及精密仪器、仪表等的精确温控,并归纳出热电制冷的关键技术问题和今后的发展方向.

  18. Quantitative research

    DEFF Research Database (Denmark)

    Wigram, Anthony Lewis

    2003-01-01

    possible and desirable. It is not just a type of research done in a laboratory, or by PhD students. Some for of reliable measurement can be applied to many clinical situationsto evaluate the effects of therapy over time, or the difference between clients who receive therapy and those who don't. Evaluating...

  19. Research Application Paper

    Science.gov (United States)

    Baskas, Richard S.

    2011-01-01

    The purpose of this study is to compare and contrast two types of scholarly article designs, quantitative and qualitative, as to how two research designs can be similar and different, and how the authors conduct their research and present their results. When researching and analyzing two scholarly articles of different design types, it is…

  20. State of the educational research project: “the efficacy and the quality of skill acquisition in rural education: is this model transferable to different types of schools?”

    Directory of Open Access Journals (Sweden)

    Laura Domingo

    2012-09-01

    Full Text Available The paper presents a State of the Art regarding the research project “the efficacy and the quality of skill acquisition in rural education: is this model transferable to different types of schools?” (EDU2009-13460, Subprograma EDUC. This 3-year project was funded by the Spanish Ministry of Science and Innovation, within the Work Programme of the National R&D&I Plan for Fundamental Oriented Research Projects. The study, now in its third year, was carried out in both Latin America and Europe. It analyses the skill acquisition of primary students in rural schools in Chile, Uruguay, France, Portugal and Spain, according to the active and participatory didactic methodologies that were applied in specific schools and in relation to the degree of influence each local territory has at a cultural-pedagogical level. This study uses an interpretive paradigm, combining quantitative methods such as the design and application of a survey, and qualitative techniques including semi-structured interviews and ethnography. The investigation is now in its last phase, during which we will carry out an analysis of documents and participant observation. The results intend to show whether the pedagogic model found in rural schools that use participatory and active didactic methodologies is transferable to urban schools, and will generate conclusions that will aid in improving the quality of education in schools of all types.

  1. 祁门县文堂村木活字印刷技艺调查研究%The Research of the Wooden Movable Type Printing Craftsmanship from Wentang Village Qimen County

    Institute of Scientific and Technical Information of China (English)

    方晓阳; 吴丹彤

    2013-01-01

    木活字印刷术自发明以来,流布甚广,代有传承,时有创新。通过实地考察,对文堂村木活字印刷者所供奉的神祇、印刷物料、排版工具、刷墨工具以及印刷技艺等进行了较为深入的研究。指出文堂村木活字印刷技艺具有一定地方特色,部分工具与技艺具有独特性,是一种值得传承与保护的现存木活字印刷技艺之一。%The wooden movable type printing has been spread, succeeded and innovated since it was invented. According to review on the spot and research into the shrine, printing material, typesetting and brushing ink tool as well as the printing craftsmanship. Researchers came to the conclusion that the wooden movable type printing from 文堂village祁门county has some local color and particularity. It deserve protection and succession.

  2. 缺铁性贫血与补铁剂研究概况%Research progress on iron deficiency anemia and new types of iron supplement agents

    Institute of Scientific and Technical Information of China (English)

    赵聪; 黄浩; 陈贵堂

    2016-01-01

    key study object for scientists. This article mainly summarized iron deficiency anemia and human health, the development history of iron supplement agents, and the recent research of polysaccharide-iron complex, ferrous-chelating peptides and iron-enriched yeast.

  3. 缺铁性贫血与补铁剂研究概况%Research progress on iron deficiency anemia and new types of iron supplement agents

    Institute of Scientific and Technical Information of China (English)

    赵聪; 黄浩; 陈贵堂

    2016-01-01

    becoming the key study object for scientists. This article mainly summarized iron deficiency anemia and human health, the development history of iron supplement agents, and the recent research of polysaccharide-iron complex, ferrous-chelating peptides and iron-enriched yeast.

  4. Type inference for correspondence types

    DEFF Research Database (Denmark)

    Hüttel, Hans; Gordon, Andy; Hansen, Rene Rydhof

    2009-01-01

    We present a correspondence type/effect system for authenticity in a π-calculus with polarized channels, dependent pair types and effect terms and show how one may, given a process P and an a priori type environment E, generate constraints that are formulae in the Alternating Least Fixed-Point (A...

  5. 中国城市女性面部皮肤状态与中医体质类型相关性研究%A Relevant Research on Facial Skin Conditions of Chinese Urban Females and TCM Constitutional Types

    Institute of Scientific and Technical Information of China (English)

    曲建宁; 王济; 赵亚; 熊卫国; 方程; 戴竞; 孙淑娴; 王琦; 魏少敏

    2014-01-01

    目的:研究面部皮肤状态与中医体质类型的相关性,为从中医体质角度指导皮肤养护、增进皮肤健康提供新方法。方法在9个省会城市和直辖市招募女性志愿者2241名,以网络问卷的方式对受访者进行调查。体质类型判定依照中华中医药学会《中医体质分类与判定》标准进行,面部皮肤测评针对肤色、光泽度、细腻程度、水润度、紧致程度、弹性、均匀程度等指标进行评分;将皮肤状态按1~3、4~6、7~9分进行分组,比较不同分值的体质构成差异。结果被调查者中阳虚质、平和质最多;肤色偏黄者最多,其次为偏白、偏黑、偏红者;皮肤状态评分1~3分者中,阳虚质最多,气郁质次之;4~6分者中阳虚质和平和质均较多;得分7~9分者中平和质最多。结论平和质者各项皮肤指标得分均最高,偏颇体质会影响皮肤指标得分,对中国城市女性面部皮肤指标影响较大的体质类型是阳虚质和气郁质。%Objective To study the relationship between facial skin conditions and TCM constitutional types; To provide new means and methods for guidance of skin conservation and skin health improvement from the aspect of constitutional types. Methods Totally 2241 female volunteers in nine provincial capital cities and municipalities participated in this research, and were investigated by web questionnaire. Constitutional types were determined according to the“Classification and Judgment of TCM Constitutional Types”standard issued by China Association of Chinese Medicine. Skin color, glossiness, delicate degree, moistness, firmness, resilience, uniformity and other indicators were scored. Skin conditions were classified into three groups:1-3 score group, 4-6 score group, and 7-9 score group, and the constitutional differences among each group were compared. Results Yang-deficiency and mild constitutional types accounted for the largest

  6. Research on the Mechanism and Control Measuresof Dike Pit type Slide in the Yangtze River%长江大堤窝崩机理与控制措施研究

    Institute of Scientific and Technical Information of China (English)

    金腊华; 石秀清; 王南海

    2001-01-01

    在归纳总结各种关于江河大堤窝崩成因解释的基础上,对河堤窝崩的机理进行了理论分析,据此解释了长江马湖堤最近窝崩的形成原因;并根据模型试验和实际应用实践的结果,提出了一种行之有效的治理和预防大堤窝崩的工程措施。%Based upon the results of summing-up the research status about the mechanism and the causes of dike pit type slide in the Yangtze River, the mechanism of dike pit type slide has been analyzed theoretically according to the elementary theory of river bed deformation and soil mechanics. The cause of the recent dike pit type slide occurred at the Mahu Reach in the Yangtze River has been demonstrated. One effective measure has been found to control dike pit slide based upon the results of sediment model experiments and actual。

  7. Preliminary Research of the Regular Pattern between Flavonoids Content and the Age of Erect Type Ophiopogon jaonicus%直立型川麦冬黄酮含量变化规律的初步研究

    Institute of Scientific and Technical Information of China (English)

    郭星; 程方叙; 廖政; 张兴国; 曹原湘; 文便便

    2008-01-01

    [Objective] The experiment aimed to inquire into the regular pattern of the flavonoids content in erect type Ophiopogon jaonicus preliminarily. [Methods] In the main Ophiopogon jaonicus-produeing area, we use the method of home position dynamic method to gather sample for experiments, use UV to determine the flavonoids content in Ophiopogon jaonicus and use correlation and regression method to analyze the relation between flavonoids content and the growth period of Ophiopogon jaonicus. [Results] The relation between flavonoids content(y1) and the growth period(x//d) of erect type Ophio-pogon jaonicus is: y=1. 235 61nx-4.748 9(n=7, 50 ≤x≤730, 0≤y≤3. 128, r0.001=0.950 7, r=0.954 2). [Conclusion] During a determinate time (50≤x≤730), positive correlation exists between flavonoids content and the growth period of Ophiopogon jaonicus. Our research has a great importance in directing the scientific harvest and GAP production of erect type Ophiopogon jctonicus.

  8. Ⅱ型糖尿病与肠道菌群及益生菌的相关性研究进展%Research progress on relationship between type 2 diabetes, gut microbiota and probiotics

    Institute of Scientific and Technical Information of China (English)

    郭霄; 张勇; 郭建林; 孙天松

    2013-01-01

    Type 2 diabetes is a common chronic metabolic diseases with complex pathogenesis.Gut microbiota plays an important role in the early onset and deterioration of the diabetes.As an effective means of regulating gut microbiota,probiotics are living organisms that are primarily used in the prevention and alleviation of type 2 diabetes by improving the intestinal permeability,regulating the serum lipids,enhancing immunity and other mechanisms.In this review,we discuss the research advance about links between the gut microbiota and type 2 diabetes as well as the role ofprobiotics in recent years.%Ⅱ型糖尿病是一种常见的慢性代谢性疾病,其发病机制十分复杂,其中肠道菌群在其发病早期和加重过程中都起着重要的作用.益生菌作为调节肠道菌群的有效手段,可以通过改善肠道通透性、调节血脂、增强机体免疫力等多种机制对Ⅱ型糖尿病起到预防和改善作用.现就近年来肠道菌群和2型糖尿病的相关性以及益生菌的作用研究进展作一综述.

  9. Collaborative Chat Reference Service Effectiveness Varies by Question Type for Public Library Patrons. A review of: Kwon, Nahyun. ʺPublic Library Patronsʹ Use of Collaborative Chat Reference Service: The Effectiveness of Question Answering by Question Type.ʺ Library & Information Science Research 29.1 (Mar. 2007: 70‐91.

    Directory of Open Access Journals (Sweden)

    Stephanie Hall

    2008-03-01

    Full Text Available Objective – To assess the effectiveness of a collaborative chat reference service in answering different types of question. Specifically, the study compares the degree of answer completion and the level of user satisfaction for simple factual questions vs. more in‐depth subject‐based reference questions, and for ‘local’ (pertaining to a particular library and non‐local questions.Design – Content analysis of 415 transcripts of reference transactions, which were also compared to corresponding user satisfaction survey results.Setting – An online collaborative reference service offered by a large public library system (33 branch and regional locations. This service is part of the Metropolitan Cooperative Library System: a virtual reference consortium of U.S. libraries (public, academic, special, and corporate that provides 24/7 service.Subjects – Reference librarians from around the U.S. (49 different libraries, and users logging into the service via the public library system’s portal (primarily patrons of the 49 libraries. Method – Content analysis was used to evaluate virtual reference transcripts recorded between January and June, 2004. Reliability was enhanced through triangulation, with researchers comparing the content analysis of each transcript against the results of a voluntary exit survey. Of 1,387 transactions that occurred during the period of study, 420 users completed the survey and these formed the basis of the study, apart from 5 transactions that were omitted because the questions were incomprehensible. Questions were examined and assigned to five categories: “simple, factual questions; subject‐based research questions; resource access questions; circulation‐related questions; and local library information inquiries” (80‐81. Answers were classed as either “completely answered, partially answered or unanswered, referred, and problematic endings” (82. Lastly, user satisfaction was surveyed on three

  10. 肠道菌群与2型糖尿病研究进展%Research progress of the relationship between intestinal flora and type 2 diabetes mellitus

    Institute of Scientific and Technical Information of China (English)

    李文婷; 潘道延; 陈远程; 李章芳; 沈洁

    2015-01-01

    2型糖尿病是一种代谢疾病,其发病率日益增加,造成了巨大的社会经济负担.肠道菌群指定居于人体肠道的微生物群体,作为与人类紧密联系的环境因素,参与人体生长发育、生理过程,甚至疾病状态.近年来关于肠道菌群与2型糖尿病的关系的研究已经成为内分泌代谢领域的热点问题.本文拟就2型糖尿病与肠道菌群的关系做一综述,梳理该方面研究的最新进展,提示这一领域的进一步研究方向.%Type 2 diabetes is a metabolic disease with increasing prevalence,which causes great socioeconomic burden.Intestinal flora is the microbiota located in the human intestines,which are participating in human growth and development,physiological procedures,or even pathogenesis as a closely connected environmental factor.There have recently been rapid progresses in the research on the relationship between intestinal flora and type 2 diabetes in the field of endocrinology and metabolism.In this article,we reviewed the overall framework and research progress in the relationship between intestinal flora and type 2 diabetes,aiming to shed some light on the future research about this topic.

  11. 猪圆环病毒2型病毒样颗粒研究进展%Research Progress on Virus-like Particles of Porcine Circovirus Type 2

    Institute of Scientific and Technical Information of China (English)

    谢小红; 胡意

    2016-01-01

    猪圆环病毒2型(PCV2)是引起猪圆环病毒相关疾病的主要病原体,给养殖业造成重大经济损失。一直以来,对于PCV2的防控主要通过疫苗接种。目前使用的疫苗可大致分为全病毒灭活疫苗、嵌合病毒疫苗、重组亚单位疫苗三大类。病毒样颗粒(VLPs)作为一种伪病毒,以其高免疫原性、高安全性成为新型疫苗的研究热点。本文综述了VLPs在国内外的最新研究动态、研究和开发的意义,提出了VLPs作为一种基因转载工具,其研究为疫苗研发开拓了新的方向。%Porcine circovirus type 2(PCV2)is the main etiological agent of PCV2-associated diseases(PCVAD), causing enormous economic loss in pig industry. By far,vaccination is the major prevention and control measure against PCVAD. There are three kinds of vaccines applied in production at present,including inactivated whole-virus vaccine,mosaic virus vaccine and recombinant subunit vaccine. As a type of“fake”virus,PCV2 VLPs(virus-like particles)has become a hot research topic in the development of new vaccines,due to its advantages of better immunogenicity and higher security than traditional vaccines. In this article,the newest research trends and significance of research and exploitation were given a review. At the end,a conclusion was drawn:as a tool of genetic transfer vector,the research of VLPs would open up a new direction for the vaccine research and development.

  12. 多遇地震作用下板式楼梯与框架共同工作性能研究%Research on the collaborate performance of board type stairs and frame in frequent earthquakes

    Institute of Scientific and Technical Information of China (English)

    张然; 张新培; 田志鹏

    2013-01-01

    In this paper, two five layers of reinforced concrete frame models of excluding stair and containing two type stair are established to do the frequent earthquake effect of elastic time history analysis according to the limitation of recent researchs, then we discuss the effect of the frame force resulted from the collaborate of board type stairs and frame, including the seismic response in each part of board type stairs. The conclusion shows that the frame force changes largely in the parts directly linking to board type stairs,the force in the beams, pillars and boards of the stairs increases obviously comparing with their static force, pull and pressure force of the stair board become larger.%针对目前地震作用下板式楼梯框架地震反应研究不足的现状,本文建立了不含楼梯和含两个板式楼梯的两个5层钢筋混凝土框架模型,并进行了多遇地震作用下的弹性时程分析,讨论了板式楼梯与框架共同工作时对框架梁柱内力的影响以及楼梯各构件的地震反应,结果表明,直接与楼梯构件连接的框架梁柱的内力受到较大影响,楼梯梁、梯柱以及梯板的内力绝对值相比静力计算的值有明显增大,梯板存在较大拉压力.

  13. 肾精亏虚型与肝阳上亢型血管性认知障碍的听力差异性临床研究%Clinical research on difference of dysaudia form cognitive impairment between the Shenjing Kuixu type and the Ganyang Shangkang type

    Institute of Scientific and Technical Information of China (English)

    程永华; 胡丹华; 靳楠楠

    2016-01-01

    Vascular cognitive impairment is a common disease in the department of geriatrics. Hearing disorder is a common clinical symptom of vascular cognitive impairment; vascular cognitive impairment is increasing with ages. Listening is an important source of accessing to outside stimulation; if hearing disordered, the quality of daily life will be declined. According to TCM therapy, the Shenjing Kuixu type and the Ganyang Shangkang type were common clinical syndromes of vascular cognitive impairment. Difference of dysaudia form cognitive impairment between the Shenjing Kuixu type and the Ganyang Shangkang type was found by MMSE simple cognitive scale and pure - tone audiometric equipment. After research, cognitive ability is lower and listening is also more loss in the Shenjing Kuixu type.%血管性认知障碍是老年病科的常见病。听力下降是血管性认知障碍的常见临床症状,血管性认知障碍随着人均寿命的延长呈现不断上升的趋势。听力是获取外界认知刺激的重要来源,听力的下降会降低患者的日常生活质量。根据中医分型,肾精亏虚型和肝阳上亢型属于血管性认知障碍的常见证型。使用MMSE简易认知量表对认知能力进行分析,使用纯音听力设备进行听力学分析,运用统计软件进行统计,发现其中的关系。肾精亏虚型认知能力低于肝阳上亢型,听力方面也差于肝阳上亢型。

  14. Type Tricks

    DEFF Research Database (Denmark)

    Beier, Sofie

    2017-01-01

    an expert as a typography professor, Sofie Beier knows exactly what the students need to know and how they can improve their skills. ‘Type Tricks’ is not only perfect for students, it also comes in handy for every type designer. It gives them the opportunity to reread information they were thaught at during...

  15. Research Suggestions for Students

    Science.gov (United States)

    Holland, John L.

    1974-01-01

    Describes how to perform accurate research. Also includes suggestions for specific research projects under such headings as: (1) types; (2) environments; (3) interactions; (4) classification; (5) hexagonal model; and (6) differentiation. (HMV)

  16. Quantitative research

    DEFF Research Database (Denmark)

    Wigram, Anthony Lewis

    2003-01-01

    possible and desirable. It is not just a type of research done in a laboratory, or by PhD students. Some for of reliable measurement can be applied to many clinical situationsto evaluate the effects of therapy over time, or the difference between clients who receive therapy and those who don't. Evaluating......Music therapy is well recognised as a profession now, and there is increasing interest in the effect of treatment over time, as well as the way that treatment works. Evidence Based Practice (EBP)looks for various types of evidence, and quantifying the benefits and value of music therapy i both...

  17. 外智引联型创新团队研究述评与发展动态分析%Research Review and Dynamic Analysis of Intelligence Alliance Type Innovation Team

    Institute of Scientific and Technical Information of China (English)

    段万春; 曹勤伟; 杜凤娇

    2016-01-01

    为弥补当前学界对跨区域多主体创新团队研究的不足并有效解决西部经济持续发展中高端人才匮乏的现实问题,提出了外智引联型创新团队的新型合作模式.为深入系统地剖析外智引联型创新团队研究现状,首先从创新团队的定义、问题、影响因素及运行机制4个方面对相关理论研究成果进行了梳理,然后从创新团队指标体系和模型构建两个维度对创新团队模型研究成果进行了归纳和动态分析,最后从团队人才引进与管理、协作交互影响、合作效果评价、知识转移4个方面对创新团队管理的研究成果进行了探讨.在此基础上,结合外智引联团队的地域性、灵活性等独特属性进行了深入研究.%In order to compensate for the current academic research on cross-regional and multi-agent innovation team and effective to solve the deficiency of high level talent and unsustainable economic development in w estern areas ,it puts for-ward the intelligence alliance type innovation team of the new cooperation pattern .On the basis ,it systematically analyzes the intelligence alliance team research situation .First of all ,it introduce the definition ,problems ,influencing factors , mechanism four aspects related to its theoretical research and dynamic analysis of innovation team in colleges and universi-ties ,and then from the index system and model with two dimension of innovation team ,it summarizes the research a-chievements and dynamic analysis ,finally from team talent introduction and management ,collaborative interaction effect , cooperation effect evaluation ,four aspects of innovation team knowledge transfer team management research results are discussed and the dynamic analysis .On this basis ,it combines with intelligence alliance innovation team regionalist ,flexi-bility ,in depth research on the unique attributes to rich the theory system of innovation team and enhance the level of uni

  18. Comparative analysis of knowledge translation of health technology assessment research between different types of research institues%不同类型研究机构卫生技术评估研究结果转化情况的比较研究

    Institute of Scientific and Technical Information of China (English)

    刘文彬; 施李正; 庞伟明; 董恒进; 陈英耀

    2015-01-01

    Objective: To compare the differences in health technology assessment ﹙HTA﹚ knowledge translation between different types of research institutes and provide some scientific evidences to expand HTA impact in the process of policy-making. Methods: A self-administered questionnaire survey was implemented to domestic HTA researchers. Likert scores were applied to describe the situation of HTA knowledge translation. Rank-sum test was conducted to compare the differences. Results: While the differences in research utilization were not statistical significant, some significant differences were found between researchers from university and researchers not from university in the aspects of organizational knowledge translation support, research uptake process, cognition of knowledge translation, output forms of research outcomes, quality of HTA research. Conclusion: It is recommended to establish the knowledge translation support mechanism for HTA research outcomes, strengthen the collaborations and communications between HTA researchers and policy-makers, promote their cognition of HTA knowledge translation in the process of decision-making, and adopt various output forms of research outcomes more appropriately and effectively.%通过对不同类型研究机构的卫生技术评估(HTA)研究结果转化情况的比较,为扩大HTA的决策使用提供科学依据。采用自设问卷,开展针对国内HTA研究者的问卷调查,通过Likert五分法描述HTA研究结果转化情况,运用秩和检验进行差异分析。虽然在HTA转化利用方面的差异尚无统计学意义,但在组织支持、研究过程、认知水平、研究产出方式、研究质量方面,来自高校和非高校机构研究者之间的一些差异均有统计学意义。为促进HTA研究结果的决策转化,建议确立促进HTA决策转化的支持机制,强化与决策方的沟通交流协作,提高转化认知水平,采用适宜且多样的研究结果产出方式。

  19. Types of Research Bias Encountered in IR.

    Science.gov (United States)

    Gabr, Ahmed; Kallini, Joseph Ralph; Desai, Kush; Hickey, Ryan; Thornburg, Bartley; Kulik, Laura; Lewandowski, Robert J; Salem, Riad

    2016-04-01

    Bias is a systemic error in studies that leads to inaccurate deductions. Relevant biases in the field of IR and interventional oncology were identified after reviewing articles published in the Journal of Vascular and Interventional Radiology and CardioVascular and Interventional Radiology. Biases cited in these articles were divided into three categories: preinterventional (health care access, participation, referral, and sample biases), periinterventional (contamination, investigator, and operator biases), and postinterventional (guarantee-time, lead time, loss to follow-up, recall, and reporting biases). Copyright © 2016 SIR. Published by Elsevier Inc. All rights reserved.

  20. Management of sporadic desmoid-type fibromatosis: a European consensus approach based on patients' and professionals' expertise - a sarcoma patients EuroNet and European Organisation for Research and Treatment of Cancer/Soft Tissue and Bone Sarcoma Group initiative.

    Science.gov (United States)

    Kasper, B; Baumgarten, C; Bonvalot, S; Haas, R; Haller, F; Hohenberger, P; Moreau, G; van der Graaf, W T A; Gronchi, A

    2015-01-01

    Desmoid-type fibromatosis (DF) is a rare monoclonal, fibroblastic proliferation characterised by a variable and often unpredictable clinical course. It may affect nearly all parts of the body including extremities, trunk and abdomen. Considering the variable clinical presentations, anatomic locations and biological behaviours, an individualised treatment approach is required. No established or evidence-based approach for the treatment of this neoplasm is available as of today. Therefore, we propose a consensus treatment algorithm based on a round table meeting bringing together sarcoma experts from the European Organisation for Research and Treatment of Cancer (EORTC) Soft Tissue and Bone Sarcoma Group (STBSG) with patient advocates from Sarcoma Patients EuroNet (SPAEN). The aim of the meeting was to develop - for the first time ever - a consensus approach based on professionals' AND patients' expertise. As a fundamental prerequisite, all patients should be discussed in a multidisciplinary setting in centres or professional networks with a specific expertise in the disease.

  1. Research on TiO2 scanning mode during E type electron gun evaporation plating%TiO2在e型电子枪蒸镀时扫描模式的研究

    Institute of Scientific and Technical Information of China (English)

    宋佳妮; 刘凯; 闫文平

    2015-01-01

    This article is mainly to research the TiO2 scan mode setting during evaporation e type electron gun , in order to adjust the TiO2 characteristics in the vacuum coating, guarantee the relatively stable good condition of TiO2 during the film deposition.%本文主要是对TiO2在e型电子枪蒸镀时的扫描模式设定进行了研究,以此来调整 TIO2在真空镀膜时的特性,保证TiO2在形膜过程中获得相对稳定的良好状态。

  2. Progress in Research of Laser’ s Effect on Collagen Types of Hypertrophic Scar%激光对增生性瘢痕胶原类型的影响与研究进展

    Institute of Scientific and Technical Information of China (English)

    张斐; 谭军

    2014-01-01

    将近年来各种类型激光治疗对增生性瘢痕中Ⅰ型及Ⅲ型胶原表达与比例变化的影响及研究进展进行较为系统的分析、总结和归纳,为临床上选择有效的增生性瘢痕的治疗方案提供参考。%Systematic analysis, summary and conclusion was done in terms of the influences of various laser thera-pies on expression and ratio of collagen type Ⅰ and Ⅲ in hypertrophic scar as well as related research progress, providing reference for selecting effective therapeutic regimen of hypertrophic scars in clinic.

  3. Type-indexed data types

    NARCIS (Netherlands)

    Hinze, R.; Jeuring, J.T.; Löh, A.

    2002-01-01

    A polytypic function is a function that can be instantiated on many data types to obtain data type specific functionality. Examples of polytypic functions are the functions that can be derived in Haskell, such as show, read, and ‘==’.More advanced examples are functions for digital searching, patter

  4. Advancing Ethical Neuroscience Research.

    Science.gov (United States)

    Borah, B Rashmi; Strand, Nicolle K; Chillag, Kata L

    2016-12-01

    As neuroscience research advances, researchers, clinicians, and other stakeholders will face a host of ethical challenges. The Presidential Commission for the Study of Bioethical Issues (Bioethics Commission) has published two reports that provide recommendations on how to advance research endeavors ethically. The commission addressed, among other issues, how to prioritize different types of neuroscience research and how to include research participants who have impaired consent capacity. The Bioethics Commission's recommendations provide a foundation for ethical guidelines as neuroscience research advances and progresses.

  5. Pollutant Types

    Science.gov (United States)

    Describes the types of air pollutants, including common or criteria pollutants, and hazardous air pollutants and links to additional information. Also links to resources on other air pollution issues.

  6. Fiscal 1997 international cooperation project. Report on the results of the research on environmental harmony type combustion technology; 1997 nendo kokusai kenkyu kyoryoku jigyo. Kankyo chowagata nensho gijutsu ni kansuru kenkyu kaihatsu seika hokokusho

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1998-03-01

    Out of the R and D on the environmental harmony type combustion technology, the results of the project carried out in fiscal 1997 were summed up. In the site survey, etc., visits were paid to France, Spain, Greek, Germany, the U.K. and the U.S. to have discussions and examine the trend of research on the NOx removal catalyst and catalyst combustion. In the actual R and D, the R and D were conducted on zeolite base NOx removal catalyst, oxide composite base NOx removal catalyst, alumina base NOx removal catalyst, direct decomposition type NOx removal catalyst, catalyst combustion, etc. In the R and D of the catalyst combustion, durability under high gas flow flux was examined of PdO-Pt/Ba-Al203 catalyst developed for low temperature use, which indicated that durability and low temperature activity were heightened. As high temperature use catalyst, high temperature durability was examined of the developed Pd0-La/Gd-ZrO2 catalyst, which showed that the durability was favorable. 322 refs., 261 figs., 55 tabs.

  7. Vision, Implementation Challenges and Research Approaches of China’s New-type Urbanization%中国新型城镇化的蓝图构建、实施挑战与研究策略

    Institute of Scientific and Technical Information of China (English)

    诸大建

    2014-01-01

    From the perspective of urban studies and public policy analysis, this paper discusses three critical issues of China’s new-type urbanization. As to the vision, some relation between urbanization and economy, society, environment, culture and politics are studied one by one.About implementation, some chalenges such as scale, structure, efifciency and quality of population entering urban areas are examined in detail. For research approaches, the method of backcasting is suggested to make a bridge between the present situation and vision of China’s new-type urbanization.%从城市研究和公共政策分析的角度,讨论了中国新型城镇化的3个基本问题。在发展目标方面,逐一讨论了人口进城与社会建设、经济建设、生态建设、文化建设、政治建设的关系;在实施挑战方面,深入讨论了人口进城落户的规模、结构、效率、质量问题;在研究策略方面,指出中国新型城镇化需要运用回溯比对型方法在愿景与现状之间发现有效的通道和工作空间。

  8. The Design Research of a New-Type Steel Pipe Communication Tower%一种新型钢管通信塔的设计实践研究

    Institute of Scientific and Technical Information of China (English)

    于送洋

    2012-01-01

    Communication Tower ofLuchao Port in Donghai Bridge in Shanghai is a steel pipe tower with a new structural type. The height of the tower is 90.75 meters, all is assembled with tubes. The shape of the tower is differrent from the conventional tower it looks like a people erecting next to the East China Sea Bridge. There are four different sections of the total structure of the tower. In the design stage, some achievement after the research and optimization about the type of the tower, the calculation of the wind force, the analysis of the structure and the conformation of the joints are got.%上海东海大桥芦潮港综合通信塔采用了一种新型钢管结构的塔型.塔高90.75m,全钢管结构,全塔结构分为四个区段.此塔造型采用了有别于常规塔型的结构形式,立面外形成人字形竖立在东海大桥旁,在设计过程中,对结构形式、风荷载计算、结构分析及节点构造等进行了研究和优化,取得了较为理想的成果.

  9. Research on Two Types of Buffer Zone Impact on Surrounding Office Space Environment in Winter in Cold Climate Zone-a Fieldwork in Architectural Design Institute Building of Tsinghua University, Beijing

    Institute of Scientific and Technical Information of China (English)

    YeHao Song; JunJie Li; Ning Zhu; JiaLiang Wang; ShiMeng Hao

    2014-01-01

    Building buffer zone space is not only one of essential approaches for better mental quality of interior building space, but also an important factor that may influence interior thermal comfort and energy consumption. This study aims to analyze regulative advantages of buffer zone to the surrounding functional spaces. Based on a fieldwork test in a typical office building in cold climate zone in Beijing, China, the monitor data show interior physical performance in the Winter. The research selects two types of different buffer zones in the same building. One is a south⁃faced greenhouse which has large dimension with plenty of vegetation, and the other is a simple atrium in the middle of five floor building with mount of skylights. The factors and their influence to surrounding functional spaces and the whole building are found out from the comparisons of collected data by floor to floor monitor test on both buffer zones at the same time. The comparisons of two types of buffer zones conclude that the greenhouse is more effective to air quality regulation but not so clearly well⁃performed to thermal buffering as expected due to the dominate active central heating in the Winter. This fieldwork test results for building performance can be helpful for both architects and engineers in the early phase of sustainable design.

  10. Research and development of utilization technology of solar thermal energy system for industrial and other use. Research and development of solar system (investigation of popular type snow melting systems); Sangyoyo nado solar system jitsuyoka gijutsu kaihatsu. Solar system no chosa kenkyu (fukyugata yusetsu system no kenkyu chosa)

    Energy Technology Data Exchange (ETDEWEB)

    Takita, M. [New Energy and Industrial Technology Development Organization, Tokyo (Japan)

    1994-12-01

    Described herein are the results of the FY1994 research program for investigation for popular type snow melting systems using solar energy. Two types of technologies are proposed to utilize solar energy for snow melting in winter and create comfortable environments. One is combined (active plus passive) type, which transfers solar heat it collects by the whole wall surfaces to an attic to heat it totally, and makes the whole roof as a radiator to melt snow. However, heat radiated from the roof is insufficient to melt all snow on the roof, allowing it to remain to an extent that it works as an insulator. The other is active type, which transfers heat it collects by the collector to the heat storage tank, from which heat is extracted in winter for various purposes, including snow melting. Such a system must store heat for an extended period, for which a highly insulating heat storage tank is proposed to balance capacity of heat storage between seasons and building size.

  11. Research progress of effects of botulinum toxin type A on hypertrophic scar%A 型肉毒毒素对增生性瘢痕影响的研究进展

    Institute of Scientific and Technical Information of China (English)

    陈晓娟; 周国富; 向小燕; 张兰

    2016-01-01

    Hypertrophic scar is a hyper-proliferative disorder of the fibrous connective tissues,which protrudes above the skin surface.Patients with hypertrophic scars are clinically characterized with deformity, restricted range of motion,pain and pruritus.Although multiple treatments are currently available including surgical excision,steroid injection,radiation therapy,laser and pressure therapy,the most effective option re-mains to be explored.In recent years,many scholars have demonstrated that botulinum toxin type A can pre-vent and treat hypertrophic scar.This article reviewed the research progress on the relationship between botuli-num toxin type A and hypertrophic scar,and briefly summarized the correlation between botulinum toxin type A,cytokines and skin tension.%增生性瘢痕是纤维结缔组织过度增生性疾病,突出于皮肤表面,临床表现为畸形、功能障碍、疼痛和瘙痒等,治疗方法有手术、激素、放射治疗、激光及压力疗法等,目前尚无有效的方法。近年陆续有不同学者研究发现 A 型肉毒毒素能够预防和治疗增生性瘢痕,该文通过综述近年来 A 型肉毒毒素与增生性瘢痕关系的研究进展,简要总结 A 型肉毒毒素与细胞因子、皮肤张力之间的关系。

  12. AgNOR在不同类型子宫内膜增生症中的定量研究及意义%Quantitative research of AgNOR in different types of endometrial hyperplasia.

    Institute of Scientific and Technical Information of China (English)

    周秋霞; 李卫东

    2011-01-01

    To study the value of quantitative research of AgNOR in different types of endometrial hyperplasia. Methods 200 patients who were diagnosed as endometrial hyperplasia were divided into normal hyperplasia group, simple hyperplasia group, complex hyperplasia group and atypical hyperplasia group, with 50 cases in each group. Quantitative research and morphometric analysis of AgNOR were taken in different endometrial tissues with silver-staining technique. Results There were differences in dimensions, shape, localization in cell of AgNOR among atypical hyperplasia group and the other three groups. AgNOR count had no statistical differences in normal hyperplasia group (1.52+0.31, range 1.22~2.36, cutoff value3.15) increased significantly (P0.05;正常增生组、单纯增生组与复杂增生组比较P<0.05;正常增生组、单纯增生组与不典型性增生组比较P<0.01;复杂增生组与不典型性增生组比较P<0.05.结论 AgNOR颗粒的数量可为临床治疗和随访提供量化依据,可以作为子宫内膜增生预后的评价指标.

  13. Research and Exploration of Computer Applied-Type Talents Training Mode in the Private University%民办高校计算机应用型人才培养模式研究与探索

    Institute of Scientific and Technical Information of China (English)

    向亦斌

    2014-01-01

    Chinese higher education has been focused on developing basic scientific research and teaching expertise, but doesn't pay enough atten-tion to how to meet the needs of industrial and mining enterprises. According to characteristics of the non-governmental institutions, com-bining network engineering specialty in application-oriented research and exploration on the mode of talent cultivation. Proposes reforma-tion of computer applied-type talents cultivation and practice of talent training model of architecture, links teaching system and teaching reformation of the basic framework and method.%我国高等教育一直侧重于培养基础科学研究和教学专门人才,对如何适应工矿企业的需要没有给予足够的重视。根据民办高校的特点,结合在网络工程专业应用型人才培养模式上的研究与探索,提出计算机专业培养应用型人才的改革思路、人才培养模式总体结构、实践环节教学体系基本框架及教学改革的方式方法。

  14. Facts about Type 2

    Medline Plus

    Full Text Available ... Professional Books Patient Access to Research Student Resources History of Diabetes Resources for School Projects How to Reference Our ... most common form of diabetes. In type 2 diabetes, your body does not use insulin properly. This is called insulin resistance. At first, ...

  15. Facts about Type 2

    Medline Plus

    Full Text Available ... org > Diabetes Basics > Type 2 Share: Print Page Text Size: A A A Listen En Español Facts ... 2 Recently Diagnosed Treatment and Care Blood Glucose Control Complications Medication Doctors, Nurses & More Enroll ... Cost of Diabetes Advocate Toolkit Call to Congress Research & ...

  16. 中医传统功法应用于2型糖尿病患者的研究进展%Research progress of traditional Chinese exercises applying to the patients with type 2 diabetes

    Institute of Scientific and Technical Information of China (English)

    沈意娜; 刘宇; 何巧

    2016-01-01

    本文对中医传统功法在2型糖尿病患者中的研究进展进行了综述。中医传统功法如八段锦、太极拳、五禽戏对2型糖尿病患者在血糖和糖化血红蛋白的控制方面都有积极的作用,其中对八段锦的研究最多,此功法还对2型糖尿病患者情绪、睡眠等方面有积极影响,但这些功法作用机制方面的研究少见。易筋经、六字诀应用于2型糖尿病患者的研究较少,可能与其功法的流传与普及度较低有关。由于中医传统功法种类繁多,其运动形式多种多样,因此需要制定运动指南,在运动强度、频率、时间等方面对患者进行指导。%The paper reviewed the research progress of traditional Chinese exercises applying in the patients with type 2 diabetes.Traditional Chinese exercises such as Baduanjin , Tai Chi, Wuqinxi have positive effect on controlling blood glucose and glycosylated hemoglobin of diabetic patients , and most studies focused on Baduanjin, which also had positive effect on mood , sleep and other aspects of type 2 diabetes.However, the studies on mechanism of these exercises were few .The research on Yijinjing and Liuzijue applied in the patients with type 2 diabetes were few , and it may be related to their unpopularity .Due to the wide range of traditional Chinese exercises and sports are in many forms , it is necessary to make a guideline to guide the patients in exercise intensity , frequency , time and other aspects .

  17. 腐败心理的类型和结构--基于“贪官忏悔录”的研究%The Types and Structures of Corruption Psychology-a Research based on“Confessions of Corrupt Officials”

    Institute of Scientific and Technical Information of China (English)

    龙太江; 韦焱良; 李艳

    2016-01-01

    This paper selects 365 copies of“Confessions of Corrupt Officials”from the Justice Network as a research sample. This paper combines the paradigm of quantitative research and qualitative analysis by taking a combination of theoretical and empirical research. The paper analyzes the corruption psychology of 365 corrupt offi-cials, and then theoretically elaborates the structures and the types of corruption psychology. Corruption psychology contains two kinds of first-level psychology which is consisted of several kinds of low-level psychology. Corruption psychology consists of dynamic structure,adjusting structure and characteristic structure.%本文选取正义网365份“贪官忏悔录”作为研究样本,采取理论与实证相结合、定量的数量统计与定性分析相结合的研究范式,对365名落马官员的腐败心理进行分析,在此基础上对腐败心理的结构和类型进行理论化阐述:腐败心理由主动型腐败心理和被动型腐败心理两个一级心理类别所构成,一级心理类别之下还分别包括若干次级心理类别。腐败心理由动力结构、调节结构和特征结构等三大结构所组成。

  18. Translating Comparative Effectiveness Research Into Practice: Effects of Interventions on Lifestyle, Medication Adherence, and Self-care for Type 2 Diabetes, Hypertension, and Obesity Among Black, Hispanic, and Asian Residents of Chicago and Houston, 2010 to 2013.

    Science.gov (United States)

    Rashid, Jamila R; Leath, Brenda A; Truman, Benedict I; Atkinson, Donna Durant; Gary, Lisa C; Manian, Nanmathi

    In the United States, racial/ethnic minorities account for disproportionate disease and death from type 2 diabetes, hypertension, and obesity; however, interventions with measured efficacy in comparative effectiveness research are often not adopted or used widely in those communities. To assess implementation and effects of comparative effectiveness research-proven interventions translated for minority communities. Mixed-method assessment with pretest-posttest single-group evaluation design. US Department of Health and Human Services, Office of Minority Health, research contractor, and advisory board; health centers, including a federally qualified community health center in Chicago, Illinois; and public housing facilities for seniors in Houston, Texas. A total of 97 black, Hispanic, and Asian participants with any combination of health care provider-diagnosed type 2 diabetes, hypertension, or obesity. Virtual training institutes where intervention staff learned cultural competency methods of adapting effective interventions. Health educators delivered the Health Empowerment Lifestyle Program (HELP) in Chicago; community pharmacists delivered the MyRx Medication Adherence Program in Houston. Participation rates, satisfaction with interventions during January to April 2013, and pre- to postintervention changes in knowledge, diet, and clinical outcomes were analyzed through July 2013. In Chicago, 38 patients experienced statistically significant reductions in hemoglobin A1c and systolic blood pressure, increased knowledge of hypertension management, and improved dietary behaviors. In Houston, 38 subsidized housing residents had statistically nonsignificant improvements in knowledge of self-management and adherence to medication for diabetes and hypertension but high levels of participation in pharmacist home visits and group education classes. Adaptation, adoption, and implementation of HELP and MyRx demonstrated important postintervention changes among racial

  19. Research on the Improvement of Reproduce Performance by the Application of Type-B Ultrasonic Technology in Scaled Dairy Farms%应用B超技术提高规模奶牛场繁殖性能的研究

    Institute of Scientific and Technical Information of China (English)

    郑博文; 王少华; 王建勇; 张勇峰; 王光文; 袁耀明; 李胜利

    2011-01-01

    The research was conducted to three thousand-scale dairy farms which belongs Bright Dairy Food Co.,Ltd,for type-B ultrasonic technology practical application,for the three dairy farms of different years compare no using with using the type-B ultrasonic technology after breeding,respectively,at the 30 day for the early pregnancy diagnosis,early detection and timely processing of open cows breeding again in the pregnancy to reduce the empty cup feeding costs.Through the type-B ultrasonic technology applications and to collect breeding rate,conception rate and reproduction rate of inspection data analysis and comparison,in the production practice and achieved good results.Type-B ultrasonic technology applied to the three thousand-scale dairy farms into practical which can promote the breeding rate,the first farm is 21%(P0.01),the second is 21%(P0.01),and the third is 19 %(P0.05),respectively;promote the circumstances of the conception rate of the average monthly,the first farm is 3%(P0.05),the second is 6%(P0.05),and the third is 3%(P0.05),respectively;and promote the total fertility rate,the first farm is 5.1%,the second is 7.6%,and the third is 7.1%,respectively.Type-B ultrasonic technology for the heifers on early pregnancy diagnosis and reproductive management,the effect is not obvious(P0.05).In the case study,at the reduced breeding in the southern summer heat conditions,type-B ultrasonic technology increased average breeding rate which is 3.1% from June to November and we compared 30 days after mating pregnancy diagnosis using type-B ultrasonic technology with the retest by rectal examination by hand the 60-day,difference we can see space for 60 days until check has lower pregnancy rate,which is decreased 25.65%.Among 30-60-day embryo loss rate is 4.92%,which reflected the dairy farm's herd quality and management overall in a good condition.%本研究针对上海光明荷斯坦牧业有限公司三个千头规模牧场进行B超技

  20. Research on PCR determining of type b Haemophilus influenzae strains and immunogenicity of polysaccharide conjugates%几株b型流感嗜血杆菌多糖结合物的免疫原性检定

    Institute of Scientific and Technical Information of China (English)

    袁玉兰; 郭京蓉; 周继唯; 高华

    2012-01-01

    Objective To determine Haemophilus influenzae type b strains in molecular level using PCR,and to study the immunogenicity of capsular polysaccharide conjugates in mice.Methods Extracting genomes using bacterial DNA extract kit from Hoemophilus influenzae type b strains,and PCR for determining the strains through serotyping-specific and capsular genotyping primers respectively.Various capsular polysaccharides conjugated TT respectively,and the conjugates were administered subcutaneously to mice through dilution.After vaccination with two doses,blood samples were collected for the detection of antibody levels to polyribosylribitol phosphate ( PRP),the capsular polysaccharide of Hib.Results All five Haemophilus influenzae type b strains contain type-specific(482 bp) and capsular type (343 bp)DNA fragment through PCR detecting.The DNA fragments were sequenced.BLAST show that these sequences are 100% homology comparing the above strains respectively,and are 99% and 100% homology comparing the GenBank X78559.1 and M19995.1 respectively.The immunogenicity of mice from various capsular polysaccharide conjugates (PRP-TT) was not significantly different by ELISA detecting.Conclusion Through PCR,Haemophilus influenzae type b strain can be determined in molecular level.The immunogenicity of mice from purified capsular polysaccharide conjugates was not different.The study provides a detection means for the features and heredity stability of Haemophilus influenzae type b strain and reference data for the immunogenicity of different polysaccharide conjugates in vaccine research and development and production.%目的 从分子水平检定b型流感嗜血杆菌,研究不同菌株荚膜多糖结合物的免疫原性.方法 提取基因组,通过型特异和荚膜型基因特异引物,利用PCR检定b型流感嗜血杆菌;不同纯化多糖分别与破伤风类毒素(TT)进行耦联结合,结合物原液经稀释免疫小鼠,通过两针免疫,采血进行免疫效力测定.

  1. 京冀平原区不同类型农户耕地利用研究%Research on Different Types of Farm Household Cultivated Land Use in Jinji Plain Area

    Institute of Scientific and Technical Information of China (English)

    李翠珍; 孔祥斌

    2012-01-01

    Farmer households were divided into three group types in the light of their preference for grain or monetary production capacity, the succession relation between household group types and their land use objectives in different phases was discussed. The land use characteristic of each group type was discussed, taking Daxing County, Haidian County in Beijing, and Quzhou County in Hebei Province as study areas with household survey carried out in 2008. The results indicated that:1 In metropolitan suburb, households preferring for grain productivity and profit accounts for more than 40 percent, and approximately 50 percent of households have transformed into the type of demanding for profit; in Situan, Quzhou, farm households shows great preference of grain productivity and profit at the same time; by comparatively, Haidian is the closest district to the city center, households type here show diversification, especially about one third households pay more attention to farmland security function because of lower land stability. 2 During the households transition from the type of demanding for grain productivity to the type of preferring grain productivity and profit simultaneously, or from the formers to the type of demanding for profit, planting structure u-sually shows decrease in grain crop sown area and increase in cash crop sown area, and farmers' agricultural income is increasing step by step. 3The production function regression results of different household types shows that: farmland size has limited farmer income increase to some extent, and household type of preferring grain productivity and profit simultaneously and type of demanding for profit are all prone to labor-intensity crops and intensive land use pattern. Research on household land use from the prospective of household types would favor the study of land use change driving mechanism.%从农户对粮食生产能力和价值生产能力偏好的角度对农户进行群体分类,分析不同时期农

  2. DiversiLab typing research of Staphyloccocus aureus strains isolated from food samples%对食品中分离的金黄色葡萄球菌进行DiversiLab分型研究

    Institute of Scientific and Technical Information of China (English)

    刘静宇; 凌莉; 陈春梅; 易敏英; 胡科峰

    2012-01-01

    Objective:To conduct molecular typing research for the 16 Staphyloccocus aureus strains isolated from food samples of Zhanjiang, in order to trace food borne diseases and provide early warning. Methods: DiversiLab Automated typing system was used to study the genotypes of the 16 Staphyloccocus aureus strains. Results: According to the diagnostic criteria, the 16 Staphyloccocus aureus strains were distributed to nine patterns. Among them, pattern 1 contained strains 0902 and 0901 ; Pattern 2 contained strains 0971, 0923, 0967, 09108 ; Pattern 3 contained strains 0969 , 0970, 10010; Pattern 4 contained strains 09118 and 09119. The rest five strains were distributed to five different patterns. Conclusion: DiversiLab typing results revealed the genetic characters and relationships of the 16 Staphyloccocus aureus strains accurately. The convenient and efficient DiversiLab automated typing system is a powerful molecular genotyping tool to monitor food borne pathogens as well as trace and warn food borne diseases.%目的:对来自湛江的食品样本中分离的16株金黄色葡萄球菌进行DiversiLab分型,研究其基因特征和聚类分布,为食源性疾病溯源及预警提供依据.方法:采用DiversiLab自动分型系统对16株金黄色葡萄球菌进行分子分型.结果:DiversiLab分型系统将16株金黄色葡萄球菌分为9个型别,其中P1型包含菌株0902和0901;P2型包含0971、0923、0967、09108菌株;P3型包含菌株0969、0970、10010;P4型包含菌株09118和09119.其余5株金黄色葡萄球菌的每一个菌株被分为一个单独的型别.结论:DiversiLab分型结果准确揭示了16株食品中金黄色葡萄球菌的遗传特征和亲缘关系;Diversilab自动化分型技术方便快捷、结果可靠,是监测分析食源性致病菌和对食源性疾病溯源及预警的有力工具.

  3. Final Technical Report for Interagency Agreement No. DE-SC0005453 “Characterizing Aerosol Distributions, Types, and Optical and Microphysical Properties using the NASA Airborne High Spectral Resolution Lidar (HSRL) and the Research Scanning Polarimeter (RSP)”

    Energy Technology Data Exchange (ETDEWEB)

    Hostetler, Chris [NASA Langley Research Center, Hampton, VA (United States); Ferrare, Richard [NASA Langley Research Center, Hampton, VA (United States)

    2015-01-13

    Measurements of the vertical profile of atmospheric aerosols and aerosol optical and microphysical characteristics are required to: 1) determine aerosol direct and indirect radiative forcing, 2) compute radiative flux and heating rate profiles, 3) assess model simulations of aerosol distributions and types, and 4) establish the ability of surface and space-based remote sensors to measure the indirect effect. Consequently the ASR program calls for a combination of remote sensing and in situ measurements to determine aerosol properties and aerosol influences on clouds and radiation. As part of our previous DOE ASP project, we deployed the NASA Langley airborne High Spectral Resolution Lidar (HSRL) on the NASA B200 King Air aircraft during major field experiments in 2006 (MILAGRO and MaxTEX), 2007 (CHAPS), 2009 (RACORO), and 2010 (CalNex and CARES). The HSRL provided measurements of aerosol extinction (532 nm), backscatter (532 and 1064 nm), and depolarization (532 and 1064 nm). These measurements were typically made in close temporal and spatial coincidence with measurements made from DOE-funded and other participating aircraft and ground sites. On the RACORO, CARES, and CalNEX missions, we also deployed the NASA Goddard Institute for Space Studies (GISS) Research Scanning Polarimeter (RSP). RSP provided intensity and degree of linear polarization over a broad spectral and angular range enabling column-average retrievals of aerosol optical and microphysical properties. Under this project, we analyzed observations and model results from RACORO, CARES, and CalNex and accomplished the following objectives. 1. Identified aerosol types, characterize the vertical distribution of the aerosol types, and partition aerosol optical depth by type, for CARES and CalNex using HSRL data as we have done for previous missions. 2. Investigated aerosol microphysical and macrophysical properties using the RSP. 3. Used the aerosol backscatter and extinction profiles measured by the HSRL

  4. Case Study Research Methodology in Nursing Research.

    Science.gov (United States)

    Cope, Diane G

    2015-11-01

    Through data collection methods using a holistic approach that focuses on variables in a natural setting, qualitative research methods seek to understand participants' perceptions and interpretations. Common qualitative research methods include ethnography, phenomenology, grounded theory, and historic research. Another type of methodology that has a similar qualitative approach is case study research, which seeks to understand a phenomenon or case from multiple perspectives within a given real-world context.

  5. Registering Researchers in Authority Files

    NARCIS (Netherlands)

    Altman, M.; Conlon, M.; Cristan, A.L.; Dawson, L.; Dunham, J.; Hickey, T.; Hook, D.; Horstmann, W.; MacEwan, A.; Schreur, P.; Smart, L.; Smith-Yoshimura, K.; Wacker, M.; Woutersen, S.

    2014-01-01

    Registering researchers in some type of authority file or identifier system has become more compelling as both institutions and researchers recognize the need to compile their scholarly output. The report presents functional requirements and recommendations for six stakeholders: researchers, funders

  6. Research progress of the relationship between chronic periodontitis and type 2 diabetes mellitus%慢性牙周炎与2型糖尿病的关系研究进展

    Institute of Scientific and Technical Information of China (English)

    陈汀兰; 宋忠臣; 束蓉

    2015-01-01

    慢性牙周炎(chronic periodontitis,CP)与糖尿病(diabetes mellitus,DM)关系密切,其相互影响是近年来牙周医学研究的热点。DM是 CP 的危险因素之一,可通过多种机制促进 CP 发生发展,同时 CP 也是 DM 的第6大并发症,可影响 DM 病程进展,约90%以上的 DM为2型糖尿病(type 2 diabetes mellitus,T2DM),本文就 CP 和 T2DM相互影响的特点及机制等方面的研究进展作一综述。%Chronic periodontitis (CP)and diabetes mellitus (DM)are closely related,and the interplay between the two has become a hot topic in periodontology.DM,one of the risk factors for CP,can promote the occurrence and development of CP through several mechanisms.In turn,as the sixth complications of DM,CP can affect the progression of DM,and over 90% DM patients suffer from type 2 diabetes mellitus (T2DM).This paper will review the research progress of the relationship between CP and T2DM in terms of their characteristics,mechanisms and so on.

  7. Fiscal 1998 achievement report on regional consortium research and development project. Venture business raising type regional consortium - small business creating base type (Research and development of Peltier actuating device-aided advanced medical and welfare systems - 2nd year); 1998 nendo Peltier undo soshi wo mochiita kodo iryo fukushi system no kenkyu kaihatsu seika hokokusho. 2

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2000-03-01

    Efforts are made to develop a new Peltier actuating device by amalgamating a Peltier device and shape memory alloy and to apply the product to medical and welfare activities. In the development of active movement control for a Peltier actuating device, a multiaxial control system is developed, and a success is attained in high-speed and high-precision control of temperature and in current- and voltage-aided control of the behavior. In the development of an active actuator for catheters, an active catheter is developed for the first time, capable of performing twisting and bending simultaneously. In the development of an artificial heart catheter, an approximately 10cm-long Peltier actuating device is manufactured to serve as an artificial heart module, and a controller is developed to drive the module at the frequency of approximately 0.5Hz. In the development of shape memory alloys and Peltier devices for normal temperature actuation, the impact is examined of the addition of a third element on the transformation temperature and shape memory characteristics. Research and development is also carried out for element technologies for using a Peltier actuating device as an artificial muscle. (NEDO)

  8. 国外2型糖尿病治疗部分新药的临床研发动态%Clinical Research and Development of New Drugs for Type 2 Diabetes Mellitus

    Institute of Scientific and Technical Information of China (English)

    雷帅兵

    2015-01-01

    目的:探讨国外2型糖尿病治疗新药的研发的成果和治疗效果。方法选取我院自2012年3月~2013年3月收治的2型糖尿病患者124例作为研究对象,随机将其分成两组,即对照组患者62例采用胰高血糖素样肽-1(简称 GLP-1)受体激动剂进行治疗,观察组患者采用二肽基肽酶-4(简称 DPP-4)抑制剂治疗,对比两组患者的治疗效果。结果对照组患者的治疗有效率为46.77%,观察组患者的治疗总有效率为48.39%,两组数据对比差异不具有统计学意义,P >0.05。结论国外对于2性糖尿病治疗药物的研究明显迈进了新的台阶,其中GLP-1药物和 DPP-4药物在治疗的过程中均有非常好的效果。%Objective To investigate the results and treatment effect of foreign type 2 diabetes treatment for new drugs. Methods 124 cases of type 2 diabetic patients as the research objects were divided into two groups in our hospital from March 2012 March 2013, namely the control group 62 cases by glucagon like peptide-1 (GLP-1) receptor agonist treatment, the observation group were treated by dipeptidyl peptidase-4 (DPP-4) inhibitor for the treatment, compared two groups of patients with therapeutic effect. Results The effective rate of the control group was 46.77%, the total effective rate of the observation group was 48.39%, the difference of the two groups was not statistically significant, P>0.05. Conclusion Foreign for 2 diabetes therapeutics research obviously entered the new stage, which GLP-1 and DPP-4 drug in the course of treatment were by the very good effect.

  9. Research on Types of Same-Generated Groups from the Perspective of Subculture%高校亚文化视角下同辈群体类型研究

    Institute of Scientific and Technical Information of China (English)

    温丽芸

    2012-01-01

    The author has done comprehensive and thorough research on types and causes of formation of informal groups of university students from the perspective of subculture,with a purpose of distinguishing complicated relationships among stu-dents so as to promote a healthy and harmonious development of students.The research also aims to help teachers cultivate a new point of view of students,so as to be able to understand and accept the subculture of university students.In this way,the subculture of university students develops.By eliminating the negative effects and bringing into play the positive effects,the subculture of university students can become indispensable complement to the main stream of student cultures.%本文从大学生亚文化的角度对高校中存在的大学生同辈群体的类型及其成因进行了比较全面而深入的研究,旨在辨识和把握学生之间的复杂关系,实现学生关系和谐健康发展,促使教师形成新的学生观,并能够理解和接纳大学生亚文化,给大学生亚文化一定的发展空间,消除它给大学生带来的负面影响,充分发挥其正面作用,将积极的大学生亚文化作为大学生主流文化的有益补充,丰富大学生文化生活。

  10. Experimental Research on New Type of Concrete-filled Steel Tubular Column Joint to RC Beam%新型钢管混凝土梁柱节点试验研究

    Institute of Scientific and Technical Information of China (English)

    陈玉泉; 张倩; 薛玉丽; 雷冬

    2013-01-01

    提出了一种新型的开大孔钢筋贯通式钢管混凝土节点,该新型节点形式与已应用到工程中的开小孔钢筋贯通式节点相比,具有施工方便的优点.建立了介于这种新节点与传统开小孔节点之间的过渡形式:开大孔加强式钢筋贯通的钢管混凝土节点.并通过对三种节点低周反复循环加载的试验研究,得到如下结论:新型开大孔式节点位移延性、耗能能力比较理想,抗震性能良好,符合抗震设计的要求.在该新型节点处设加强环和加劲肋能够显著提高节点的整体性与延性.研究结果可以为其在工程中的应用提供有价值的参考.%A new type of connection between concrete-filled steel bar and concrete frame beam with steel bar run-through joint was put forward according to the present joints. Big holes were cut in the steel tubular wall of core area of the joint. Compared with the joint which small holes were set in the steel tubular wall for steel bar running through, the new type joint was more easily to be constructed. And a transient joint was made to characterize with big holes and strengthening ring and stiffing ribs. Low cycle fatigue tests were implemented to analysis these three joints and the following conclusions were given; the displacement ductility and the ability of energy dissipation of this new type joint are more ideal and seismic behavior is better which all satisfied the requirement of the structural seismic design. The stiffening ring and stiffing ribs fixed on the joint both can improve its integrity and ductility significantly. Research results can provide theoretical and experimental reference to the engineering application.

  11. Original Research Original Research

    African Journals Online (AJOL)

    RAGHAVENDRA

    Official International Journal of Wollega University, Ethiopia ... College of Medical and Health Sciences, Wollega University,. Post Box No: 395, Nekemte, ... rts Research Journal. 5, 4(2): .... Scientific Research & Innovation 3(6): 251-256. Evans ...

  12. Experimental Research on Suction and Blast Self-Balance U-Type Radiant Tube Burner%抽鼓自平衡式U型辐射管烧嘴的实验研究

    Institute of Scientific and Technical Information of China (English)

    易敏

    2012-01-01

    The experimental research was carried on suction and blast self-balance U-type radiant tube burner, and the adjustment methods of the zero pressure surface of the burner were got from the experiment. The experiment showed that, by the way of combining the suction and blast of the air, and adding the Staged combustion device simultaneously, the premise of negative pressure in the radiant tube could be ensured, the preheating temperature and temperature efficiency were increased, and the surface temperature distribution of the radiation tube was improved. At the same time, the staged combustion had important effect on the formation of Nox.%对抽鼓式U型辐射管烧嘴进行了实验研究,通过实验得到辐射管内零压面的调节手段.实验表明,采用鼓风和吸风相结合的供风方式,同时添加分级燃烧装置,能够在保证辐射管内负压的前提下,提高换热器预热温度和温度效率,改善辐射管的表面温度分布.同时分级燃烧对抑制NOx的生成有重要的作用.

  13. 微型波力发电装置的捕浪器研究%Research on Wave-capturing Device of the Floating Micro-type Device for Wave-activated Power Generation

    Institute of Scientific and Technical Information of China (English)

    李驰; 苏毅; 姬龙; 郭显成

    2013-01-01

    Based on the floating micro-type device for wave activated power generation,the float of wave-capturing device is studied. According to the Froude-krylov assumption,the wave forces on several commonly used float are calculated,and it is con-cluded that the vertical cylindrical float can absorb the wave energy most effectively. Based on the principle that when the device and float come about resonance,the float can absorb the maximum energy the basic parameters of vertical cylindrical float has been designed for further research and use.%针对漂浮式微型波力发电装置,根据弗汝德·克雷洛夫假定法对几种常用形状浮子所受波浪力的大小进行了计算,得出垂直圆柱形浮子吸收波浪能效果最佳的结论;运用装置和浮子共振时吸收能量最大的原理,对垂直圆柱形浮子的基本参数进行了研究,为漂浮式微型波力发电装置捕浪器浮子的设计打下了基础。

  14. 大型臂式斗轮堆取料机液压系统节能研究%Research on Energy-saving for hydraulic system of large-scale boom-type bucket-wheel stacker /reclaimer

    Institute of Scientific and Technical Information of China (English)

    徐万鑫

    2013-01-01

    With continuous increasing of people' s energy-saving and environmental protection awareness, energy consumption takes up more and more share in the competitive bidding for large-scale boom-type bucket-wheel stacker/reclaimer. The paper analyzes the factors affecting the energy consumption of the hydraulic system, with research on main low-efficient hydraulic systems from reduction of system power consumption and improvement of system efficiency to incorporation of the energy-saving design concept, in order to realize the energy-saving and consumption reduction for large-scale bucket wheel stacker/reclaimer.%随着人们节能环保意识的不断提高,能耗作为主要指标在大型臂式斗轮堆取料机产品的竞标中所占份额逐年增大.本文在充分分析液压系统能耗影响因素的前提下,从降低系统功耗和提高系统效率两方面入手,融入节能设计理念,对效率较低的各主要机构液压系统进行分析研究,从而实现了大型斗轮堆取料机液压系统的节能降耗.

  15. 某型号收割机割刀机构及其传动部件惯性力平衡的研究%Research on Inertia Force Equilibrium of Cutter and Transmission Parts in a Type of Harvester

    Institute of Scientific and Technical Information of China (English)

    许汝炜; 王俊田

    2015-01-01

    针对某型号收割机割刀执行及传动机构的实际工作中的性能需求,在完成机构惯性力最小的基础上,考虑实际工作情况权衡各方面因素的部分平衡的最优方案,最终得出了最优的设计参数,其研究方案可为类似杆机构惯性力平衡问题提供有益的参考。%Aiming at the performance requirements of the cutter execution and transmission mechanism in a type of harvester at the actual working process, and on minimum inertia force of the complete organization, the optimal design parameters are con-cluded with consideration of the actual working condition and the optimal solution of partial equilibrium on the various aspects, and such research programme could be beneficial reference for the similar equilibrium problems of inertia force.

  16. Progress in researches on the relationship of vaspin with obese and type 2 diabetes%vaspin与肥胖及2型糖尿病相关性研究进展

    Institute of Scientific and Technical Information of China (English)

    黄仕鹏; 刘建英

    2012-01-01

    内脏脂肪特异性丝氨酸蛋白酶抑制剂(vaspin)是近年来新发现的从肥胖糖尿病大鼠内脏脂肪组织中分离出的脂肪因子.vaspin与肥胖,IR密切相关.大量研究表明,vaspin具有改善胰岛素敏感性作用,同时可以改善糖耐量,调节糖,脂代谢.进一步深入研究vaspin作用机制,可为今后T2DM的诊治提供新的思路.%Visceral adipose tissue-derived serine protease inhibitor (vaspin) is a newly discovered adipokine that have been isolated from the visceral fat tissue of obese diabetic rats. Vaspin is closely related with obesity and insulin resistance. Large amount of studies showed that vaspin could increase the insulin sensitivity, improve the glucose tolerance, and regulate the glucose and lipid metabolism. The further and deep researches on vaspin mechanism would provide a new method of diagnosis and treatment for type 2 diabetes.

  17. Research on New Type Installation Workmanship of Heavy (Big) Shaft and Stern Tube Assembly%重(大)型轴系及艉管总成的新型安装工艺研究

    Institute of Scientific and Technical Information of China (English)

    祝腾; 陈猛

    2016-01-01

    重(大)型轴系及艉管总成(整体艉轴管)是船海工程动力推进系统非常重要的部分,其快速、便捷的安装,可以加快船海工程推进系统及整体建造的进度。文章对重(大)型轴系及艉管总成的安装工艺开展研究,对比江南长兴的新型安装工艺与传统安装方法,详细介绍了江南长兴的新型安装工艺如何快速便捷的开展施工。%The heavy (big) shaft and stern tube assembly (entire stern tube) is a very important part for shipping propulsion system. The quick and easy installation could improve the shipping propulsion system and entire ship building speed. The paper researches on heavy (big) shaft and stern tube assembly installation workmanship. Comparing with the new type workmanship of Jiangnan-changxing to traditional installation, the paper introduces how the new workmanship to achieve quick and easy installation.

  18. 客户组合策略的内涵、主要类型及未来研究展望%Concept, Types and Future Research Prospects of Customer Portfolio Strategy

    Institute of Scientific and Technical Information of China (English)

    崔新坤; 韩德昌

    2015-01-01

    客户组合策略是企业从整个客户群出发而进行客户组合分析和管理的策略活动,它聚焦于对客户群结构进行监测、分析和规划等. 文章对客户组合策略的文献进行了系统的回顾和梳理,归纳总结了客户组合策略的内涵及主要类型,并对客户组合策略未来的研究方向做出展望.%Customer portfolio strategy is about how firms analysis and manage customer portfolio from the entire customer base, which focuses on monitoring, analyzing and planning the customer base structure. This paper reviews the literature on the portfolio strategy, summarizes concept and types of customer portfolio strategy, and makes some prospects for the future research of customer portfolio strategy.

  19. 钢结构T型接头焊缝的分类分级及探伤问题研究%RESEARCH ON CLASSIFYING, GRADING AND ULTRASONIC INSPECTING OF T-TYPE WELD OF STEEL STRUCTRE

    Institute of Scientific and Technical Information of China (English)

    郭奇; 凡俊; 吴焕娟; 张帆

    2012-01-01

    There are different statements,which maybe are controversy with each other sometimes, in different codes, such as Technical Specification for Steel Struture of Tall Buildings. In this paer research is done on classifying,grading and ultrasonic inspecting of T-type weld of steel structre.%针对钢结构的焊接连接,各种国家、行业标准规范规程,如《高层民用建筑钢结构技术规程》(JGJ99—1998)等均提出不同的要求,以期发挥焊接连接的优异性能,同时扬长避短。但是各种标准规范规程的要求不尽相同,甚至有所冲突。探讨建筑钢结构T型接头焊缝的分类分级及超声波探伤中存在的问题。

  20. 类风湿关节炎中医证型临床分布规律研究%Research of clinical distribution law for rheumatoid arthritis in traditional Chinese medicine syndrome type

    Institute of Scientific and Technical Information of China (English)

    高建华; 张剑勇; 何伟珍; 刘珈尉; 孔卫红; 叶志中

    2012-01-01

    目的 通过临床病例调查,运用现代数理统计方法对类风湿关节炎(RA)中医证候分布规律进行研究,从而发现RA常见证候、临床症状分布规律以及证候与症状之间的关系.方法 运用临床信息采集表,对1024例RA门诊患者进行流行病学横断面调查,分析RA一般症状及证候要素的分布规律和特征,收集临床资料和中医四诊所得证候资料,对RA症状、证型、舌象、脉象及证候要素等进行统计分析.结果 关节压痛、关节肿胀、屈伸不利、恶风寒、腰膝痠软为RA常见的临床症状;舌质黯、淡、红为常见的舌象;苔白、白腻、黄为常见的舌苔;脉滑、濡细、弦为常见的脉象;脾肾亏虚证、痰湿阻络证、风寒湿痹证及湿瘀痹阻证为RA常见的证型.结论 对RA证候、证候要素及症状等分布规律的研究,有利于临床上审证求因、治病求本,从而进一步提高辨证的准确性和临床治疗效果.%Objective To find out distribution law of the common syndrome, the clinical symptoms and relationship between syndrome and symptoms and research traditional Chinese medicine syndrome type law of rheumatoid arthritis ( RA) by investigation through clinical cases and the use of statistical methods. Methods Epidemiological cross - sectional survey was completed in 1 024 RA outpatients using clinical information collection table including a-nalysis of rheumatoid arthritis generally symptoms and syndrome factor distribution regularity and features. Rheumatoid arthritis symptoms,syndrome type,tongue syndrome elements of pulse condition were statistically analyzed. Results 1 024 cases of rheumatoid arthritis case syndrome in traditional Chinese medicine distribution frequency statistics, through the analysis of the data collected information table, combining the expert opinion, the top five from high to low with symptoms of sequence for: joint swelling, joint tenderness, feel chill, flexion and

  1. Type Inference for Guarded Recursive Data Types

    OpenAIRE

    Stuckey, Peter J.; Sulzmann, Martin

    2005-01-01

    We consider type inference for guarded recursive data types (GRDTs) -- a recent generalization of algebraic data types. We reduce type inference for GRDTs to unification under a mixed prefix. Thus, we obtain efficient type inference. Inference is incomplete because the set of type constraints allowed to appear in the type system is only a subset of those type constraints generated by type inference. Hence, inference only succeeds if the program is sufficiently type annotated. We present refin...

  2. type-0

    Directory of Open Access Journals (Sweden)

    Ravi Srinivasa Rao

    2006-01-01

    modular right ideal in a near-ring are initiated. Based on these J0r(R, the right Jacobson radical of type-0 of a near-ring R is introduced. It is obtained that J0r is a radical map and N(R⊆J0r(R, where N(R is the nil radical of a near-ring R. Some characterizations of J0r(R are given and its relation with some of the radicals is also discussed.

  3. Type 1 Diabetes and Sleep.

    Science.gov (United States)

    Farabi, Sarah S

    2016-02-01

    IN BRIEF In people with type 1 diabetes, sleep may be disrupted as a result of both behavioral and physiological aspects of diabetes and its management. This sleep disruption may negatively affect disease progression and development of complications. This review highlights key research findings regarding sleep in people with type 1 diabetes.

  4. Action Type Deontic Logic

    DEFF Research Database (Denmark)

    Bentzen, Martin Mose

    2014-01-01

    A new deontic logic, Action Type Deontic Logic, is presented. To motivate this logic, a number of benchmark cases are shown, representing inferences a deontic logic should validate. Some of the benchmark cases are singled out for further comments and some formal approaches to deontic reasoning ar...... the benchmarks. Finally, possibilities for further research are indicated. In the appendix, decidability of the satisfiability of formulas is proved via a technique known from monadic First Order Logic....

  5. Analysis and Research on the Stakeholder Management Model of Energy-saving Benefit Sharing Type EPC Project%节能效益分享型EPC项目干系人管理模式分析与研究

    Institute of Scientific and Technical Information of China (English)

    何敏

    2016-01-01

    With the continuous promotion of energy conservation and emission reduction, the energy conservation mode of contract energy management has aroused widespread concern in society, at the same time, the energy-saving benefit sharing type EPC project has also been rapid development. As an important part of the EPC project, stakeholder management has an important impact on the implementation of the project and quality management. Therefore, it is necessary to conduct in-depth research on EPC project stakeholder management mode, so as to improve the management level of the contract energy management project. Based on the relevant theory of PMBOK, this paper mainly analyzes the key points in the process of stakeholder management. It hopes to improve the management quality and management level of the energy-saving benefit sharing type EPC project by the analysis of project stakeholder management mode.%随着节能减排建设工作的不断推进,在合同能源管理节能模式引起社会广泛关注的同时,节能效益分享型EPC项目也得到了飞速发展。干系人管理作为EPC项目中的重要组成部分,对项目的实施与质量管理有着重要影响,因此必须针对EPC项目干系人管理模式展开深入研究,从而提高合同能源管理项目的管理水平。本文结合PMBOK的相关理论,重点针对干系人管理过程中的关键点进行了系统的分析,希望通过文章对项目干系人管理模式的分析,能够对提升节能效益分享型EPC项目的管理质量与管理水平提供一定的帮助。

  6. Postsecondary Education--Participation and Dropping out: Differences across University, College and Other Types of Postsecondary Institutions. Culture, Tourism and the Centre for Education Statistics. Research Paper. Catalogue no. 81-595-M No. 070

    Science.gov (United States)

    Shaienks, Danielle; Gluszynski, Tomasz; Bayard, Justin

    2008-01-01

    The purpose of this paper is to capture and profile postsecondary education dropouts from three different types of postsecondary education--university, college and other types of institutions. It compares them with graduates from these three types of institutions. The analysis for this report is based on data from the Youth in Transition Survey…

  7. Postsecondary Education--Participation and Dropping out: Differences across University, College and Other Types of Postsecondary Institutions. Culture, Tourism and the Centre for Education Statistics. Research Paper. Catalogue no. 81-595-M No. 070

    Science.gov (United States)

    Shaienks, Danielle; Gluszynski, Tomasz; Bayard, Justin

    2008-01-01

    The purpose of this paper is to capture and profile postsecondary education dropouts from three different types of postsecondary education--university, college and other types of institutions. It compares them with graduates from these three types of institutions. The analysis for this report is based on data from the Youth in Transition Survey…

  8. 纵振换能器式圆筒型超声电机振动特性的研究%Research on the vibration characteristics of cylindrical type ultrasonic motor using longitudinal vibration transducers

    Institute of Scientific and Technical Information of China (English)

    刘英想; 陈维山; 杨小辉; 刘军考

    2012-01-01

    In a previous research, the authors have presented and developed a cylindrical type ultrasonic motor using longitudinal vibration transducers. Four uniform longitudinal vibration transducers are adopted in this motor to excite a bending vibration traveling wave in a cylinder with teeth. The simulation and experiment results of this motor indicate that the vibration state of the transducer is not single longitudinal vibration, but longitudinal and bending coupled vibration. This study focuses the research on the vibration state of the transducer in the previous motor. Firstly, the reason for the bending vibration of the transducer is given. Then, the effect of the coupling bending vibration on the electromechanical coupling factor of the motor and the distortion of traveling wave are studied. The study results state that the coupling bending vibration of the transducer can make the resonance frequency of the stator deviate from the resonance of the transducer and cause a distortion of traveling wave in the cylinder. Finally, new mode to excite the radial bending vibration of a cylinder by using the bending vibration of a transducer is presented.%以纵振夹心换能器式圆筒型超声电机为研究对象,对换能器的振动状态进行了分析,给出了换能器弯曲振动的产生原因;研究了耦生弯振对电机机电耦合系数以及圆筒中弯振行波质量所带来的影响,耦生弯振的存在使得定子模态特征频率偏离换能器谐振频率,并使得定子圆筒中的弯振行波产生了畸变.最后,提出一种采用换能器弯振激励圆筒径向弯振的模态组合方式.

  9. Research Progress on Oxidative Stress of Islet Beta Cells in Type 2 Diabetes Mellitus%2型糖尿病胰岛β细胞氧化应激的研究进展

    Institute of Scientific and Technical Information of China (English)

    裴晓艳; 张晓梅

    2011-01-01

    Objective:To investigate the research advancement on oxidative stress of islet beta cells in type 2 diabetes Mellitus (T2 DM).Methods:To explore the research progress on oxidative stress of islet beta cells in T2 DM from the concept of oxidative stress, the oxidative stress factors of islet beta cells and the mechanism of oxidative stress damage in islet beta cells.Results: Because of lower level of antioxidant system in beta cells of islet in T2 DM, oxidative stress will easily occur during metabolic process of hyperglycaemia and hyperlipemia.Oxidative stress impairs β - cell function through many approaches, decreases insulin synthesis and secretion, aggravates T2 DM.Conclusions: Oxidative stress will easily occur in beta cells and it is a complex progress as a result of many factors and pathways.Antioxidant application can protect β - cell function, prevent and treat the incidence and growth of T2 DM.%目的:探讨2型糖尿病(T2DM)胰岛β细胞氧化应激的研究进展.方法:从氧化应激的概念、胰岛β细胞发生氧化应激的因素、氧化应激损伤胰岛β细胞的机制三方面来探讨T2DM胰岛β细胞氧化应激的研究进展.结果:T2DM胰岛β细胞内含有较低水平的抗氧化系统, 在高糖、高脂等作用下,容易发生氧化应激反应, 氧化应激通过多种途径损伤胰岛β细胞, 使胰岛素合成分泌减少,加重T2DM.结论:T2DM胰岛β细胞容易发生氧化应激是多因素多途径共同作用的复杂过程,积极应用抗氧化剂治疗,能保护胰岛β细胞功能,预防和治疗T2DM的发生与发展.

  10. Research Progress of A2 Zr2 O7-type Rare-earth Zirconate Thermal Barrier Coatings%A2 Zr2 O7型稀土锆酸盐热障涂层研究进展

    Institute of Scientific and Technical Information of China (English)

    张红松; 杨树森; 温倩

    2014-01-01

    Searching for new ceramic materials is the most feasible method in order to resolve the defects of current thermal barrier coatings. The A2 Zr2 O7-type rare earth zirconates are regarded as the most potential candidate ceramic materials for thermal barrier coatings because of their low thermal conductivities, high thermal expansion coefficients and excellent phase stability at high temperatures. Rare-earth zirconate coatings are one of the key-research directions in thermal barrier coating field. In the current paper, the research progress at home and abroad, such as coating preparing technology, coating structure, coating properties inclu-ding thermophysical properties, mechanics and thermal erosion, were systemically summarized. The development deficiencies of rare-earth zirconate thermal barrier coatings were investigated. In the future, the preparing and post-treatment technology of rare-earth zirconate coatings should be improved. The bonding strength, working lifetime, corrosion and sintering resistance of new ther-mal barrier coatings should also be enhanced. In order to study coating properties of nano-structure thermal barrier coatings, new preparing technology must be developed. The thermal insulation, working temperature and lifetime of new thermal barrier coatings should also be improved.%综述了国内外稀土锆酸盐热障涂层在制备技术,纳米涂层,涂层结构及涂层的热物理性能、力学性能及热腐蚀性能等方面的研究成果,讨论了稀土锆酸盐热障涂层在每个方面研究存在的不足。指出未来应该进一步改善稀土锆酸盐涂层的制备工艺及后处理工艺,提高涂层的结合强度,延长涂层的服役寿命,改善涂层耐腐蚀、抗烧结等性能;开发新的涂层制备工艺,重点研究各类纳米稀土锆酸盐涂层的性能;进一步提高涂层的隔热效果、服役温度及工作寿命。

  11. 不同类型表面活性剂与蛋白质作用研究进展%Research Progress of the Interaction of Different Type Surfactants with Proteins

    Institute of Scientific and Technical Information of China (English)

    曹洪玉; 张莹莹; 唐乾; 郑学仿

    2014-01-01

    Surfactants interact with proteins in multifarious ways which depend on surfactant types, concentration, structure, and physical-chemical properties. To obtain a global overview of this process, the physicochemical properties of the interaction was began with introducing between proteins and surfactants, the recent research including the structural properties of protein-surfactant complex, the adsorption mechanisms of the complex, as well as the structural changes of proteins induced by surfactants. Then different phase behaviors and interaction mechanisms of proteins interaction were expounded with five different classes of surfactants, including anionic surfactants, cationic surfactants, zwitterionic surfactants, non-ionic surfactants, fluorine and Gemini surfactants. Recent research scope and current situation in every field had also been reviewed. Our results and methods in studying protein-surfactant interaction were systematically summarized in the suitable part.%表面活性剂和蛋白质作用的方式与表面活性剂的种类、结构、浓度和其理化性质有关。本文系统地总结了多种类型表面活性剂(阴离子型、阳离子型、两性离子型、非离子型、氟表面活性剂及 Gemini 表面活性剂)的结构特点,以蛋白质-表面活性剂相互作用的物理化学特征为出发点,综述了该体系相互作用的最新研究成果及进展,包括二者作用时所形成的复合物的结构理论,复合物的吸附机理及其作用过程中蛋白质结构的变化;结合本课题组的工作总结分析了蛋白质分别与各类表面活性剂相互作用过程中作用力特征、相行为、作用机理及应用。

  12. Research progress of heart type fat binding protein and its application in cardiac surgery%心脏型脂肪结合蛋白的研究及在心脏外科的应用

    Institute of Scientific and Technical Information of China (English)

    王石雄; 李宁荫; 高秉仁

    2012-01-01

    背景:心脏型脂肪结合蛋白是心肌细胞胞浆中含量最丰富的蛋白质之一,是心肌损伤的标志蛋白.目的:归纳总结心脏型脂肪结合蛋白的生物学结构及功能、代谢动力学、临床研究进展及其在心脏外科的应用.方法:由第一作者检索1983-01/2010-12 PubMed数据及维普数据库与心脏型脂肪结合蛋白的生物学结构及功能有关的文献,心脏型脂肪结合蛋白在心脏外科中的应用及临床上应用相关文献.英文检索词为"heart fatty acid-binding protein,creatine kinaseisoenzyme,acute myocardial infarction,coronary artery bypass grafting";中文检索词为"心脏型脂肪结合蛋白,肌酸激酶同工酶,心肌梗死,冠状动脉旁路移植术".根据纳入标准保留62篇进行论述.结果与结论:心脏型脂肪结合蛋白是一种低分子量的可溶性蛋白,较特异的存在于心肌细胞质内;正常人的血浆中不含有或含有少量心脏型脂肪结合蛋白,在心肌受损后能快速释放.心脏型脂肪结合蛋白在体外循环冠状动脉搭桥后围手术期心肌损伤鉴别中具有良好的诊断价值;可以较早快速评价体外循环瓣膜置换术心肌损伤的潜在有用指标;脂肪酸结合蛋白的升高水平可较早的判断心肌损伤的程度,从而判断术后心功能受损的程度和与心脏有关的并发症.%BACKGROUND: Heart-type fatty-binding protein is one of the most abundant proteins in the cytoplasm of myocardial cells, which is a marker protein for myocardial injury. OBJECTIVE: To summarize the biology structure and function, metabolism dynamics of heart-type fatty binding protein, and their progress in clinical research and application in cardiac surgery. METHODS: A search of PubMed and VIP databases (1983-01/2010-12) was performed by the first author for the literature of the biological structure and function of heart-type fatty-binding proteins and their application in cardiac surgery as well as other

  13. Research on a Novel Axial Field Disk Type Switched Reluctance Motor%新型轴向磁场盘式开关磁阻电机的研究

    Institute of Scientific and Technical Information of China (English)

    梅营; 潘再平

    2011-01-01

    提出了一种新型的采用三相6/4极结构的轴向磁场盘式开关磁阻电机,与前人研究较多的单相盘式开关磁阻电机相比,定、转子结构更加简单,加工成本更低,便于调速控制,且克服了单相电机不能自起动的缺陷.使用Ansoft公司的Maxwell 3D软件进行了三维有限元仿真分析,并制作实验样机,验证了电机的性能.%This paper proposed a novel axial field disk type switched reluctance motor ( AFSRM ), which has both the merit of SRM such as simple and robust structure, easy to control and the merit of disk machine such as short shaft, high torque/inertia rate. Comparing with the single phase AFSRM fully researched before, the novel AFSRM has simpler rotor and stator structure, and lower manufacturing cost. Since the novel AFSRM has 6/4 poles, it avoided the weakness of single phase AFSRM, inability to self start-up. In this paper, three-dimensional field and torque analysis of the novel AFSRM were carried out using Maxwell 3D, a 3D finite-element analysis (FEA) software. In addition, a prototype of novel AFSRM was made to validate the design and test the performance.

  14. 一种新型微波炉用高压电容的设计及一体化研究%Design and Integration Research on A New Type of High Voltage Capacitor Used in Microwave Oven

    Institute of Scientific and Technical Information of China (English)

    许国贤; 曾铭志; 李大卫

    2015-01-01

    High voltage capacitor is the key part of microwave oven, which has an important influence of the high and low energy efficiency of microwave oven. Combined with the working experience, this paper designs a kind of dry type high voltage capacitor with self-healing effect used in microwave oven, replacing the existing oil-immersed capacitor. The kindling point of this newly designed capacitor is above 900℃, which has no oil spill risk and secondary pollution caused by it;and the cost is about 5%lower than the existing capacitors. In addition, this paper has an integration research on high voltage capacitor and high voltage diode, so as to install and use easily, and improve the production efficiency.%高压电容器是微波炉的关键部件之一,对微波炉的能效高低具有重要影响。本文结合工作实际,设计了一种具有自愈性的微波炉用干式高压电容,以替代目前在用的油浸式电容。新设计的电容着火点在900℃以上,不存在漏油风险和由此造成的二次污染,且成本比在用电容低5%左右;此外,本文对高压电容和高压二极管进行了一体化设计,以便于安装使用,提高生产效率。

  15. "两创型"实践人才培养视角下的金融学"三核多维"研究%"Three Nuclear and Multidimensional"Research about Finance under the"Two Type"Practice Talent Training Perspective

    Institute of Scientific and Technical Information of China (English)

    刘晓华

    2015-01-01

    The article bases on"two type"(entrepreneurship and innovation)practice talent training as the research angle of view. At the same time,it combines with the connotation of"three nuclear and multidimensional"and foreign practice enlightenment. It reveals the problem that finance study mode does not conform to the times require,the target is not clear,the financial disciplines integrated model needs to be done. It studies the main content of financial"three nuclear and multidimensional"teaching reform and its implementing ways,for example,combination of theory and practice,experiment and training,the combination of case guidance, with special system to promote the establishment of a scientific and reasonable evaluation system.%文章以"两创型"实践人才培养为研究视角,结合"三核多维"的内涵以及国外实践的相关启示,揭示出金融学研究中存在的学习模式不符合时代需要、培养层次和目标不清晰、金融学科模式有待融合等问题,在此基础上研究金融学"三核多维"的主要内容及其实施途径:理论与实践相结合,实验和实训相结合,案例与专题做指引,系统推进科学合理的考核评价体系的建立.

  16. Research on Essential Value of Urban Design under the Background of New-type Urbanization%新型城镇化背景下城市设计的核心价值探讨

    Institute of Scientific and Technical Information of China (English)

    田宝江

    2015-01-01

    abstract This paper discusses the essential value of urban design under the background of New-type Urbanization. The influence of New-type Urbanization brings to urban design includes:the shift from incremental planning to inventory planning, ecological and sustainable development becoming the main tendency, new information technology improving the ideas and methods of urban design. The essential value of urban design must be realized before adapting the requirement of New-type Urbanization. By researching the history and the origin of urban design, this thesis explains that the basic fields of urban design are space forming and improving the quality of urban space. The essential value of urban design cannot be replaced by city planning and architectural design. As a method of design control, urban design constitutes basic rules to guarantee the basic line of the urban spatial quality. The essential work of urban design is making mechanism for space production -- the design structure, which can make the harmony of the whole space form and, present the local characteristics to the urban space.%新型城镇化对城市设计的影响主要体现在从增量规划向存量规划转变、生态和可持续发展成为城市空间发展的趋势、信息和新技术对城市设计理念和方法的提升。在此背景下,城市设计更要清晰认识自身的核心领域与价值,才能更好适应新型城镇化发展的需求。文章从城市设计历史发展和产生(源角度,阐明其核心领域在于城市空间塑造和空间质量的提高;其核心价值体现在城市规划和建筑设计所不能替代的方面,并通过设计控制手段,制定城市空间发展的基本原则,确保城市空间品质的底线。城市设计操作的核心内容是建立和制定空间生产的机制,从整体上规范、引导空间形态生产,保证城市空间整体和谐又能凸显地区个性与特色。

  17. 具有复合充填力的立式浅盆型排种器充种机理%Research on seed-filling mechanism of vertical shallow basin type seed-metering device with composite filling force

    Institute of Scientific and Technical Information of China (English)

    刘宏新; 徐晓萌; 郭丽峰; 尚家杰

    2014-01-01

    为了从力学角度研究提高机械式精密排种器的充种能力以适应高速作业需要,分析了排种器种腔内种子各方向力学特征及规律,建立型孔充填力模型,找出提高充填能力的有效途径,并以增加充填力种类为目标创新设计一种立式浅盆型排种器。其排种盘结构既能保留传统立式种盘的优点,又避免了离心力对清种产生的负面影响。运用离散元仿真分析软件EDEM(engineering discrete element method)进行仿真并用物理样机试验进一步证实了种盘转速提高时,作为复合力引入的重力与离心力的分力能明显起到保证种子完成向型孔内进入过程的作用,在高速区段平均充填率提高2.33%。该研究为机械式精密排种器的研究提供了借鉴与参考。%On account of the decreasing of filling ability of hole at high operating speed caused miss-seeding, even leaded to reduce production, mechanical precision seed-metering device was gradually eliminated from application markets. How to improve the filling ability of mechanical precision seed-metering device to meet the mechanization requirements at high operating speed was the key point of the research. Because the mechanical precision seed-metering device could only depend on gravity, centrifugal force and interaction force between the seeds to complete filling seeds, mechanics characteristics and regulation of soybean seeds which were in the cavity of seed-metering device in all directions were analyzed from the mechanics point of view. And due to the structure characteristic of seed-metering device and granular mixtures characteristic of soybean seeds, the value of filling force in the form of compressive stress was limited. In this paper the model of filling force of hole was built and it could be easily found that increasing the kinds of filling force was an effective way to improve filling ability of the mechanical precision seed-metering device

  18. Delaying or Preventing Type 2 Diabetes

    Science.gov (United States)

    ... Problems Diabetes & Sexual & Urologic Problems Preventing Type 2 Diabetes Perhaps you have learned that you have a ... I lower my chances of developing type 2 diabetes? Research such as the Diabetes Prevention Program shows ...

  19. Original Research Original Research

    African Journals Online (AJOL)

    RAGHAVENDRA

    land use type on soil productivity, the study also involve filled with soil samples ..... might have led to mineralization of organic nitrogen, which in turn has enhanced ..... carbon dynamics in corn-based agro ecosystems: results from carbon-13 ...

  20. Original Research Original Research

    African Journals Online (AJOL)

    User

    significant after adjustment of other socio demographic, K. However other variables like: types of .... Regarding food, water and personal hygiene, only few households show ... contributing factor towards the contamination of drinking water and ...

  1. Fuel safety research 1999

    Energy Technology Data Exchange (ETDEWEB)

    Uetsuka, Hiroshi (ed.) [Japan Atomic Energy Research Inst., Tokai, Ibaraki (Japan). Tokai Research Establishment

    2000-07-01

    In April 1999, the Fuel Safety Research Laboratory was newly established as a result of reorganization of the Nuclear Safety Research Center, JAERI. The laboratory was organized by combining three laboratories, the Reactivity Accident Laboratory, the Fuel Reliability Laboratory, and a part of the Sever Accident Research Laboratory. Consequently, the Fuel Safety Research Laboratory is now in charge of all the fuel safety research in JAERI. Various types of experimental and analytical researches are conducted in the laboratory by using the unique facilities such as the Nuclear Safety Research Reactor (NSRR), the Japan Material Testing Reactor (JMTR), the Japan Research Reactor 3 (JRR-3) and hot cells in JAERI. The laboratory consists of five research groups corresponding to each research fields. They are; (a) Research group of fuel behavior under the reactivity initiated accident conditions (RIA group). (b) Research group of fuel behavior under the loss-of-coolant accident conditions (LOCA group). (c) Research group of fuel behavior under the normal operation conditions (JMTR/BOCA group). (d) Research group of fuel behavior analysis (FEMAXI group). (e) Research group of FP release/transport behavior from irradiated fuel (VEGA group). This report summarizes the outline of research activities and major outcomes of the research executed in 1999 in the Fuel Safety Research Laboratory. (author)

  2. Consumer Behavior Research Methods

    DEFF Research Database (Denmark)

    Chrysochou, Polymeros

    2017-01-01

    emphasizes the discussion of primary research methods. Based on the nature of the data primary research methods are further distinguished into qualitative and quantitative. The chapter describes the most important and popular qualitative and quantitative methods. It concludes with an overall evaluation......This chapter starts by distinguishing consumer behavior research methods based on the type of data used, being either secondary or primary. Most consumer behavior research studies phenomena that require researchers to enter the field and collect data on their own, and therefore the chapter...... of the methods and how to improve quality in consumer behavior research methods....

  3. Genetics Home Reference: neurofibromatosis type 2

    Science.gov (United States)

    ... Research Institute National Institute of Neurologic Disorders and Stroke Educational Resources (9 links) Centre for Genetics Education (Australia) Disease InfoSearch: Neurofibromatosis type 2 JAMA ...

  4. Entangled research(ers)

    DEFF Research Database (Denmark)

    Brøgger, Katja; Staunæs, Dorthe

    into the world and being situated and attuned to it in specific ways through interest, fear, boredom or something else. Combing concepts from philosophy as well as psychology, the material and the affective turn allow us to rethink and elaborate on well-known discussions on qualitative research, representation......This paper takes up the challenges of analyzing how empirical knowledge is created when the research(ers) are always already “thrown into the world” (Heidegger) and thereby affectively “intra-act” (Barad) with and ‘perform’ the empirical knowledge. ‘ ‘Thrownness’ is Heidegger’s way of expressing...

  5. Typing is writing: Linguistic properties modulate typing execution.

    Science.gov (United States)

    Pinet, Svetlana; Ziegler, Johannes C; Alario, F-Xavier

    2016-12-01

    Typing is becoming our preferred way of writing. Perhaps because of the relative recency of this change, very few studies have investigated typing from a psycholinguistic perspective. In addition, and despite obvious similarities between typing and handwriting, typing research has remained rather disconnected from handwriting research. The current study aimed at bridging this gap by evaluating how typing is affected by a number of psycholinguistic variables defined at the word, syllable, and letter levels. In a writing-to-dictation task, we assessed typing performance by measuring response accuracy, onset latencies - an index of response preparation and initiation - and interkeystroke intervals (IKIs) - an index of response execution processes. The lexical and sublexical factors revealed a composite pattern of effects. Lexical frequency improved response latencies and accuracy, while bigram frequency speeded up IKIs. Sound-spelling consistency improved latencies, but had an inhibitory effect on IKI. IKIs were also longer at syllable boundaries. Together, our findings can be fit within a framework for typed production that combines the previously developed theories of spelling and typing execution. At their interface, we highlight the need for an intermediate hierarchical stage, perhaps in the form of a graphemic buffer for typing.

  6. From Action Research to Practice Research

    Directory of Open Access Journals (Sweden)

    Goran Goldkuhl

    2012-04-01

    Full Text Available Action research (AR has gained more acceptance as an approach to qualitative research in information systems (IS. The complexities of organisational and technical change makes this approach a suitable one in IS research. There are, however, still some controversies and confusions about the relation between “action” and “research”. The many types of AR and similar approaches (not labelled as AR that have emerged demands further conceptual clarification of AR. A conceptual inquiry of AR, presented in the paper, has led to the identification of several unresolved issues concerning intervention research like AR. An alternative research approach is presented: practice research. This research approach is well founded in pragmatism and it builds on the two premises: 1 to contribute to general practice through abstract and useful knowledge and 2 to study the empirical field as interconnected practices. Several important concepts of practice research are described as: local practice contribution vs. general practice contribution; theorizing vs. situational inquiry. Practice research is seen as a broader notion encompassing AR and other research approaches as e.g. design research and evaluation research. Two case examples of practice research are briefly presented and compared: one AR-based study in the social welfare sector and one evaluation study of a taxation e-service.

  7. Original Research Original Research

    African Journals Online (AJOL)

    RAGHAVENDRA

    Faculty of Education and Behavioral Science,. Abstract. The main ... Science, Technology and Arts Research Journ. Sci. .... school in the academic year of 2007 E.C. In this particular study the .... regression is designed to help make predictions.

  8. Original Research Original Research

    African Journals Online (AJOL)

    RAGHAVENDRA

    academic staff, creative new comers and open channels for promotion ... approach to research and education towards human development ...... Good Teachers in the Classroom? ... Destinations, and Determinants of Mathematics and. Science ...

  9. Original Research Original Research

    African Journals Online (AJOL)

    RAGHAVENDRA

    supply, both in quality and quantity (Adugna. As a result, livestock productivity is generally low the potential (EARO ..... Horro-Guduru livestock Production and Research Center,. Ethiopia. ... of the Second North American Tannin Conference on.

  10. Original Research Original Research

    African Journals Online (AJOL)

    RAGHAVENDRA

    Items 1 - 6 ... students' insufficient in English language background at core setbacks for effective .... language teaching is preparing learners to be able to use the language ... language. As a result, the researchers were motivated to investigate.

  11. Original Research Original Research

    African Journals Online (AJOL)

    RAGHAVENDRA

    ian Institute of Agricultural Research, Addis Ababa, Ethiopia ...... Means in a column followed with the same letters are not significantly different using ..... relationships among the nutrients of NFT-grown young ... In: Sumner, M. E. and Stewart,.

  12. Original Research Original Research

    African Journals Online (AJOL)

    RAGHAVENDRA

    camel as a source of meat through multi research into ... meat technology and marketing. ... light of animal handling ethics and welfare issues. ... 500-1500 meter above sea level (masl) and majority of .... connection with such slaughtering.

  13. Type Classes for Lightweight Substructural Types

    Directory of Open Access Journals (Sweden)

    Edward Gan

    2015-02-01

    Full Text Available Linear and substructural types are powerful tools, but adding them to standard functional programming languages often means introducing extra annotations and typing machinery. We propose a lightweight substructural type system design that recasts the structural rules of weakening and contraction as type classes; we demonstrate this design in a prototype language, Clamp. Clamp supports polymorphic substructural types as well as an expressive system of mutable references. At the same time, it adds little additional overhead to a standard Damas-Hindley-Milner type system enriched with type classes. We have established type safety for the core model and implemented a type checker with type inference in Haskell.

  14. 西北750 kV电网大容量新型FACTS设备应用研究%Applied Research on New Types of High Capacity FACTS Devices in Northwest 750 kV Power Grid

    Institute of Scientific and Technical Information of China (English)

    左玉玺; 郑楠; 范克强; 王雅婷; 邢琳; 申洪; 郑彬; 李晶; 班连庚; 周勤勇; 李润秋

    2013-01-01

      为解决西北新能源大规模外送系统的无功电压控制问题,提高电网的安全稳定性,在新疆与西北主网联网750 kV第二通道上规划装设多套可控电抗器和静止无功补偿器等大容量新型 FACTS 设备。为此提出了 FACTS 设备的技术应用方案,并对FACTS设备的稳态调压效果进行详细分析。同时从提升联网通道输电能力和提升故障后电压恢复水平2个方面研究了FACTS设备对系统暂态稳定性的提升作用。最后,从抑制系统过电压和潜供电流的角度,分析了FACTS设备对电磁暂态问题的影响。%In allusion to the control of reactive power and voltage during the large-scale transmission of power generated by new energy source base in Northwest China and to enhance the security and stability of power grid, it is planned to install multi sets of new types of high-capacity FACTS devices such as controlled shunt reactors (CSR) and static var compensators (SVC) in the second 750 kV transmission line to connect Xinjiang power grid with Northwest power grid. A technological scheme for the application of these FACTS devices is proposed and the steady-state voltage regulation effect of FACTS devices is analyzed in detail. Meanwhile, in the aspects of increasing power transmission capability of the grid-connecting channel and improving post-fault voltage recovery level, the enhancement effect of FACTS devices on power grid transient stability is researched. Finally, the influences of FACTS devices on electromagnetic transient are analyzed in the viewpoints of suppressing system overvoltage and secondary arc current.

  15. 新型数字化智能输液仪的研制及应用%The research and application of a new type of digitalized intelligent IV monitoring device.

    Institute of Scientific and Technical Information of China (English)

    华嘉临; 何茗芳; 缪学明; 冯钧; 支杨

    2011-01-01

    Objective:The goal of this research is to study and to develop a new type of digitized intelligent IV monitoring device in order to robotize the IV infusion process, to increase the safety factor, to reduce the working load of nurses, and to make patient having better rest. Methods:The method of such a device is described as the followings. The device which applies the principle of electronic load sensor consists of 5 parts: load sensor, data collector, data processor,data display including a liquid crystal display screen,a wireless transmitter and an alarming device. Results:The device can automatically monitor the whole process of an IV infusion process, including measuring the volume of the medical liquid in an IV bottle, the infusion rate, the required infusion time, and automatic alarming. Conclusions: This device applies high technology with low cost, high market demand, ease to use, and ease for market development; It would become the first candidate candidate for an IV infusion monitoring system.%目的:研制一种新型数字化智能输液监测仪,自动监测输液过程,提高安全系数,减轻护士工作负担,保证患者休息.方法:该输液监测仪采用电子称重的原理,由五部分构成:传感器、数据采集部件、数据处理部件、液晶面板显示和无线发送并报警.结果:实现对输液全过程进行自动化测试,测试输液容器容量、输液速度、需要时间、自动报警.结论:该装置技术含量高、成本低廉、实用性强、使用简便、易于推广,可成为输液监测系统的首选装置.

  16. 脊背型介质加载表面等离子体波导传输特性研究%Research on waveguide transmission characteristics of spine type medium load surface plasmon

    Institute of Scientific and Technical Information of China (English)

    郑洪全; 宁海春

    2016-01-01

    In order to reduce the transmission loss, strengthen the medium loaded plasma waveguide mode field constraint and optimize the plasma waveguide transmission performance, a further research on waveguide transmission characteristics of the dielectric loaded surface plasmon was studied. A waveguide with spine type medium load plasma was designed and the relationship between the geometric parameters and the geometrical parameters of the waveguide in the mode field distribution and its transmission parameters were studied. The simulation results show that the electric field component of the base mode is mainly distributed in the metal/dielectric layer 1 interface. As a result, the transmission characteristic of the model changes with the variations of the geometrical parameters of waveguide. Hence, the field can be effectively controlled by shifting the geometrical parameters of the waveguide and localization can be enhanced obviously.%为降低传输过程中的损耗,加强介质加载等离子体波导的模式场约束,并且优化等离子体波导的传输性能,对基于介质加载的表面等离子体波导的传输特性做了进一步的研究,设计了一种脊背型介质加载等离子体波导,并对其模式场分布及其传输参数随波导中的几何参数与电磁参数的变化关系做了相应的研究。仿真结果得出:基模的电场分量主要分布在该结构的金属/介质层1界面。该模式的传输特性,随着该波导的几何参数的变化而发生相应改变,因而可以通过改变这种结构的几何参数,对场实现有效控制,使其局域性明显增强。

  17. 布鲁氏菌BP26蛋白迟发型变态反应的研究%Research on delayed- type hypersensitivity of Brucella BP26

    Institute of Scientific and Technical Information of China (English)

    刘景福; 李恪梅; 王国治

    2011-01-01

    Objective: To research the delayed - type hypersensitivity of Brucella BP26 by skin tests in guinea pigs immunized with various Brucella antigens. Methods: Guinea pigs were immunized with BP26 and various brucella species respectively. The above - mentioned immunized guinea pigs were injected I. D. With purified protein derivative of Brucella,purified protein derivative of Br. Ml6,purified protein derivative of Br. RM6,purified protein derivative of Br. 5K/33. Results;The results of skin tests on BP26 allergen in BP26 immunized guinea pigs were positive , and those in the guinea pigs sensitized with Brucella species were negative. Nevertheless, the results of skin tests on PPD allergen was reversed. Conclusion; Brucella BP26 showed its high specific allergenicity.%目的:研究布氏菌(简称Br.)BP26蛋白在不同抗原免疫豚鼠模型上的迟发型变态反应.方法:分别用BP26重组蛋白、布氏菌纯蛋白衍生物(Br-PPD)、布氏菌M16种纯蛋白衍生物(Br.M16-PPD)、布氏菌RM6种纯蛋白衍生物(Br.RM6-PPD)、布氏菌5K/33种纯蛋白衍生物(Br.5K/33-PPD)5种变态反应原,在BP26和不同种布氏菌免疫豚鼠模型上分别进行皮肤试验.结果:变态反应原BP26蛋白在BP26免疫模型上能够形成明显的迟发型变态反应,在不同种布氏菌免疫的模型上均为阴性;各种布氏菌纯蛋白衍生物变态反应原在其相应菌种的免疫模型上形成明显的变态反应,在BP26免疫模型上均为阴性结果.结论:布氏菌BP26具有变态反应原性,其变应原性具有较强的特异性.

  18. Models and design principles for teacher research

    NARCIS (Netherlands)

    Admiraal, Wilfried; Smit, Ben; Zwart, Rosanne|info:eu-repo/dai/nl/298981823

    2014-01-01

    Teacher research is a way to bridge the gap between theory and teaching practice. Various types of teacher research can be distinguished, including most commonly: action research, selfstudy, lesson study, design-based research, and scholarship of teaching and learning. All types of teacher research

  19. Models and design principles for teacher research

    NARCIS (Netherlands)

    Admiraal, Wilfried; Smit, Ben; Zwart, Rosanne

    2014-01-01

    Teacher research is a way to bridge the gap between theory and teaching practice. Various types of teacher research can be distinguished, including most commonly: action research, selfstudy, lesson study, design-based research, and scholarship of teaching and learning. All types of teacher research

  20. Political Communication Research in the 1980s.

    Science.gov (United States)

    Meadow, Robert G.

    1985-01-01

    Discusses eight books, including a textbook for undergraduates, that represent the type of research being conducted in the political communication field. Identifies major problems of current research. (PD)

  1. Research in Public Relations

    Directory of Open Access Journals (Sweden)

    Coriolan PĂUNESCU

    2006-10-01

    Full Text Available Research has an important role in public relations (PR being necessary in developing strategies in this area. Therefore, we can speak oftwo types of research, the applied research and theoretical research, both being successfully used in the work of public relations. Applied research,can be strategic (used in programs in order to identify attitudes and opinions of the target public, to develop strategies for formulating andtransmitting messages, to establish the criteria for evaluating the work and evaluative by which it determines the communication efficiency, incarrying out the program of public relations (in fact it is the comparison between the established and achieved objectives.

  2. Original Research Original Research

    African Journals Online (AJOL)

    User

    2013-06-10

    Jun 10, 2013 ... changed in to upward trend because of HIV epidem ... strategies adequate to overcome the challenges in TB co ... Science, Technology and Arts Research ... al incidence of untreatable drug resistance strain of .... providing information on its control and prevention ..... World Health Organization (WHO).

  3. 竞争项类和对抗项类循环制竞赛中的排名方法研究%Research on the ranking method for confrontation type round -robin contest

    Institute of Scientific and Technical Information of China (English)

    王宁

    2013-01-01

      采用文献资料法和定量分析法对竞争项类与对抗项类循环制竞赛的排名方法的本质差异进行研究,结果表明:竞争项类排名方法符合“举重比赛模型”,对抗项类循环制竞赛排名方法从理论上符合“球赛模型”。%With the methods of documents review and mathematical analysis ,it deals with essential differences between the ranking methods of competition type contest and confrontation round -robin type contest .The results show: ranking method for competition type in accordance with the “ weightlifting competition model ”, ranking method for confrontation round -robin type in accordance with the “ball game model” theoretically.

  4. Guarded dependent type theory with coinductive types

    DEFF Research Database (Denmark)

    Bizjak, Aleš; Grathwohl, Hans Bugge; Clouston, Ranald

    2016-01-01

    , type based, way. Clock quantifiers are used for controlled elimination of the later modality and for encoding coinductive types using guarded recursive types. Key to the development of gDTT are novel type and term formers involving what we call delayed substitutions’. These generalise the applicative...... functor rules for the later modality considered in earlier work, and are crucial for programming and proving with dependent types. We show soundness of the type theory with respect to a denotational model....

  5. Dye solar cell research

    CSIR Research Space (South Africa)

    Cummings, F

    2009-11-01

    Full Text Available stream_source_info Cummings_2009.pdf.txt stream_content_type text/plain stream_size 3362 Content-Encoding UTF-8 stream_name Cummings_2009.pdf.txt Content-Type text/plain; charset=UTF-8 DYE SOLAR CELL RESEARCH Franscious... Cummings Energy and Processes Materials Science and Manufacturing Council for Scientific and Industrial Research P.O. Box 395 Pretoria 0001, South Africa 27 November 2009 CONTENT head2rightBackground head2rightCSIR Dye Solar Cell Research head2...

  6. TypingSuite: Integrated Software for Presenting Stimuli, and Collecting and Analyzing Typing Data

    Science.gov (United States)

    Mazerolle, Erin L.; Marchand, Yannick

    2015-01-01

    Research into typing patterns has broad applications in both psycholinguistics and biometrics (i.e., improving security of computer access via each user's unique typing patterns). We present a new software package, TypingSuite, which can be used for presenting visual and auditory stimuli, collecting typing data, and summarizing and analyzing the…

  7. 广州市不同类型屋顶绿化温湿度日变化初步研究%The Diurnal Variation Research of Temperature and Humidity of Different Types of Roof Greening in Guangzhou City

    Institute of Scientific and Technical Information of China (English)

    冼丽铧; 刘乾; 陈红跃; 沈志力; 杨水龙; 鲍海泳; 徐谙为; 覃艺伟

    2013-01-01

    为研究不同类型屋顶绿化的温湿度日变化,选择了广东省广州市越秀区地毯式、花园式和棚架式和盆花式4种不同的屋顶绿化类型,观测和统计分析不同绿化形式的屋顶及其不同空间位置的温度和湿度的变化.结果表明,各种类型的屋顶绿化对小气候都产生了显著的效应.其中,地毯式绿化类型植被覆盖度最高,降温效果最明显,温度最低;花园式和棚架式相当;盆花式效果较差,温度较高;各个测定位置的湿度数值则与温度相反,与降温效果一致.综合温湿度结果,4种屋顶绿化类型都产生了不同程度的生态效应,其中地毯式最佳,花园式和棚架式次之,盆花式较差.%For studying the diurnal variation of temperature and humidity of different types of roof greening, 4 types of green roofs including carpet, garden, frame and potted-flower in Yuexiu District of Guangzhou City were selected. The temperature and humidity changes in different types of green roofs with their locations were surveyed and analyzed. The results showed that various types of green roofs had a significant effect on the microclimate. A-mong the 4 types of green roofs, the carpet roof greening exhibited the best cooling effect with high vegetation cover. The garden and frame types were nearly the same exhibited better effect while the potted-flower type was the worst of all. The humidity measured at all types of roof garden were significantly higher than that of the exposed roof. Humidity effects were ranked as follows: carpet > garden and frame > potted-flower. In general, 4 types of roof greening had different degrees of ecological effect. Among them, carpet was the best. Garden and frame types were the secondary, while potted-flower was the poorest.

  8. Research Results Research Results

    Science.gov (United States)

    2009-04-01

    A Highly Efficient Route for Selective Phenol Hydrogenation to Cyclohexanone A Novel Mechanism Employed by KSHV to Maintain the Latent Infection was Revealed Breakthrough in the Synthesis of Interconnected NW/NT and NT/NW/NT Heterojunctions with Branched Topology GABA Transporter-1 Activity Modulates Hippocampal Theta Oscillation and Theta Burst Stimulation-Induced Long-Term Potentiation Meta-analysis of Vitamin D, Calcium and the Prevention of Breast Cancer New Findings on the Origin of TrpRS PKCd Regulates Cortical Radial Migration by Stabilizing the Cdk5 Activator P35 PKU Research Team Publishes Papers on Inhalation Exposure to Pollutant and Cancer Risk Progress of the Research on Arbitrarily Elliptical Invisibility Cloaks An Advance in Complete Oxidation of Formaldehyde at Low Temperatures

  9. 复合型组织化机制:基于高校社团的经验研究%Multi-type Organizing Mechanism:An Empirical Research Based on University Organizations

    Institute of Scientific and Technical Information of China (English)

    宿丹; 陈莹骄; 董晓雯; 赵孟营

    2014-01-01

    从组织化的理论出发,指出准组织通过在已具备的两个组织要素的基础上发展第三要素的过程使组织从准组织化状态向组织化状态转变。以大学生公益社团这一类"周期性空转"的准组织为例,从组织吸引、组织赋权、组织嵌合三个环节的组织化过程,提出发展型、价值型、人际关系型和依赖型四个类型的复合型组织化机制。%Starting from the theory of organizing,the authors of this paper point out the process in which a quasi-organization with two basic elements develops the Third Element so that the quasi-organization transforms to an organized state. Taking university nonprofit organization ,the quasi-organization facing dilemma of "cyclical idling",as example the authors studied the processes of "organizational attraction","organizational empowerment","organizational matching" and put forward four kinds of multi-type organizing mechanism which consists of development-type,value-type,relationship-type and dependence-type.

  10. 我国大学科研不端行为的类型、诱因及后果%The Types, Incentives and Effects of Research Misconduct in China' Universities

    Institute of Scientific and Technical Information of China (English)

    匡促联

    2011-01-01

    The research misconduct in China's universities is mainly shown as power rent-seeking, fraud- ulent practice, repeated bubble making and fame-and-fortune pursuit. The vague understanding of scientific value, apatheic consciousness of research rules and feelings of honor and shame in research activities are the subjective reasons that cause research misconduct. The objective reasons of research misconduct include the uniting of administration and academy, centralized operation in professional title evaluation and the inabilities from the research correction mechanism. The research misconduct will trample the dignity of scientific research, ruin the reputation of university and stop China from becoming a powerful nation of science and technology.%大学科研不端行为的类型主要有权力寻租型、弄虚作假型、重复泡沫型和追名逐利型等。科研个体主观上的科研价值认识模糊、科研规范意识淡薄、科研荣辱之情缺乏,以及高校管理体制的政学合一、高校学术职称评定的集权操作和科研纠错机制的被动无力等客观原因是诱发科研不端行为发生的重要因素。科研不端行为既践踏了科研的尊严、毁坏了大学声誉,也阻碍了科技强国,需要我们予以深切的关注。

  11. Research on the Effect of Different Thinking Types in Solving Mathematics Problems%不同思维类型对数学解题的影响研究

    Institute of Scientific and Technical Information of China (English)

    张跃红

    2015-01-01

    美国学者安东尼·格里高提出了4种不同的思维类型,即具体而有序、抽象而有序、具体而随机、抽象而随机的思维.不同的思维类型对数学解题理当产生不同的影响,通过对240名学生进行的相关调查研究,获得了一些初步的结论,并由此提出了相应的发展性策略建议,即具体而有序的思维需要提高抽象概括能力,抽象而有序的思维需要提高发散思维能力,具体而随机的思维需要提高集中概括能力,抽象而随机的思维需要提高集中思维能力.%U.S. scholar Anthony Gregory has proposed four thinking types which contained Specific and Ordered (SO), Abstract and Ordered (AO), Specific and Random (SR) and Abstract and Random (AR). It is believed that different thinking types can exert different influences in mathematics problem-solving. Based on an investigation involving 240 students, this paper concluded some preliminary findings, and therefore proposed corresponding developmental strategies: students with SO thinking type should promote abstract generalization ability; students with AO thinking type should promote divergent thinking ability; students with SR thinking type should promote concentrated generalization ability and students with AR thinking type should promote concentrated thinking ability.

  12. The use of straw to reduce the soil and water losses in agriculture and forest ecosystems in the Mediterranean Type-Ecosystem. The Soil Erosion and Degradation Research Group contribution

    Science.gov (United States)

    Cerda, Artemi; Burguet, Maria; Keesstra, Saskia; Borja, Manuel Esteban Lucas; Hedo, Javier; Brevik, Eric; Pereira, Paulo; Novara, Agata; Jordan, Antonio; Prosdocimi, Massimo; Taguas, Encarnacion

    2016-04-01

    using paired plots under natural and simulated rainfall at the Soil Erosion Stations of Montesa, El Teularet and Celler del Roure. Rainfall simulation experiments with very small (0.25 m2), small (1 m2) and medium (20 m2) plots were carried out in scrublands and recently fire-affected land, and on vineyards and orchards. The plots under natural rainfall conditions ranged from 1 to 300 m2. The results show a positive influence of the straw mulch to reduce the soil and water losses, although is more efficient to control the sediment delivery due to the reduction of the raindrop impact. Reduction in one order of magnitude is usual after the immediate application of the straw on vineyards (Prosdocimi et al., 2016) and apricots (Keesstra et al., under review) and in persimmon plantations (Cerdà et al., in press). The above-mentioned results show the positive effect of the straw mulch found by other researchers with other types of mulches such as rock fragments (Cerdà, 2001; Jordán et al., 2009; Jordan and Martínez-Zavala, 2008; Martínez-Zavala and Jordán, 2008, Zavala et al., 2010). There is a need to develop new and advanced research on the effects of the straw cover and other mulches such as litter on the recently forest fire affected soils, and pruned chipped branches and other organic amendments on agriculture land (Yazdanpanah et al., 2016). This new reseach challenge should give information about the soil and water losses, but also about the organic matter recovery, the soil water retention, and the biological, chemical and physical soil properties changes. . Acknowledgements The research leading to these results has received funding from the European Union Seventh Framework Programme (FP7/2007-2013) under grant agreement n° 603498 (RECARE project). References Berendse, F., van Ruijven, J., Jongejans, E., Keesstra, S. 2015. Loss of plant species diversity reduces soil erosion resistance. Ecosystems, 18 (5), 881-888. DOI: 10.1007/s10021-015-9869-6 Biswas H

  13. Good research guide, second edition

    CSIR Research Space (South Africa)

    Scholes, RJ

    2003-01-01

    Full Text Available stream_source_info Good Research Guide second ed. RJ Scholes (editor) 2003.pdf.txt stream_content_type text/plain stream_size 22 Content-Encoding ISO-8859-1 stream_name Good Research Guide second ed. RJ Scholes (editor) 2003.pdf....txt Content-Type text/plain; charset=ISO-8859-1 ...

  14. Research Data Services in European Academic Research Libraries

    OpenAIRE

    Tenopir, Carol; Talja, Sanna; Horstmann, Wolfram; Late, Elina; Hughes, Dane; Pollock, Danielle; Schmidt,Birgit; Baird, Lynn; Sandusky, Robert J.; Allard, Suzie

    2017-01-01

    Research data is an essential part of the scholarly record, and management of research data is increasingly seen as an important role for academic libraries. This article presents the results of a survey of directors of the Association of European Research Libraries (LIBER) academic member libraries to discover what types of research data services (RDS) are being offered by European academic research libraries and what services are planned for the future. Overall, the survey found that librar...

  15. 四梁耦合振子式超声波电动机的研制与实验%Research and Experiment on Four Beam Coupled Oscillator Model Type Ultrasonic Motor

    Institute of Scientific and Technical Information of China (English)

    张辉; 洪尚任; 鲍时超; 乔木

    2012-01-01

    The four beam coupled oscillator model type ultrasonic motor drive mechanism was studied. A new structure motor of the four beam coupled oscillator model type ultrasonic motor was designed and manufactured, and the experimental test was made. Results indicate that the type of motor was simple and compact structure, and had good performance , such as fast response speed, good control characteristics and low-speed and large torque. The expected design objective was obtained. The development of modal transformation type ultrasonic motor have practical significance and reference value.%对四梁耦合振子式超声波电动机的驱动机理进行了研究,设计并制作了四梁耦合振子式的新型结构电机,并进行了实验测试.实验结果表明,该类型电机不但结构简单紧凑,而且具有良好的输出性能,如反应速度快、控制特性好,低速大转矩等,设计达到了预期效果.该研究对模态转换型新型超声波电动机的研发有实际意义和参考价值.

  16. Empirical research on coordination evaluation and sustainable development mechanism of regional logistics and new-type urbanization: a panel data analysis from 2000 to 2015 for Liaoning Province in China.

    Science.gov (United States)

    Sun, Qiang

    2017-06-01

    As the largest developing country in the world, China has witnessed fast-paced urbanization over the past three decades with rapid economic growth. In fact, urbanization has been not only shown to promote economic growth and improve the livelihood of people but also can increase demands of regional logistics. Therefore, a better understanding of the relationship between urbanization and regional logistics is important for China's future sustainable development. The development of urban residential area and heterogeneous, modern society as well regional logistics are running two abreast. The regional logistics can promote the development of new-type urbanization jointly by promoting industrial concentration and logistics demand, enhancing the residents' quality of life and improving the infrastructure and logistics technology. In this paper, the index system and evaluation model for evaluating the development of regional logistics and the new-type urbanization are constructed. Further, the econometric analysis is utilized such as correlation analysis, co-integration test, and error correction model to explore relationships of the new-type urbanization development and regional logistics development in Liaoning Province. The results showed that there was a long-term stable equilibrium relationship between the new-type urbanization and regional logistics. The findings have important implications for Chinese policymakers that on the path towards a sustainable urbanization and regional reverse, this must be taken into consideration. The paper concludes providing some strategies that might be helpful to the policymakers in formulating development policies for sustainable urbanization.

  17. Management of sporadic desmoid-type fibromatosis: A European consensus approach based on patients' and professionals' expertise - A Sarcoma Patients EuroNet and European Organisation for Research and Treatment of Cancer/Soft Tissue and Bone Sarcoma Group initiative

    NARCIS (Netherlands)

    Kasper, B.; Baumgarten, C.; Bonvalot, S.; Haas, R; Haller, F.; Hohenberger, P.; Moreau, G.; Graaf, W.T.A. van der; Gronchi, A.

    2015-01-01

    Desmoid-type fibromatosis (DF) is a rare monoclonal, fibroblastic proliferation characterised by a variable and often unpredictable clinical course. It may affect nearly all parts of the body including extremities, trunk and abdomen. Considering the variable clinical presentations, anatomic location

  18. Structure design and simulation research on a new type of optical current sensor%一种新型光学电流传感器结构设计与仿真研究

    Institute of Scientific and Technical Information of China (English)

    2015-01-01

    本文设计对称光程反射式光学电流传感器实验系统,使用COMSOL多模场耦合仿真软件对所设计的光学传感系统的传输场进行模拟仿真,得到对称光程反射式光学电流传感器对法拉第磁光效应的响应度,其理论灵敏度高于传统结构的灵敏度580倍。未来将基于所建立的实验系统对传感器的潜在应用做进一步的深入研究。%A new structure of optical current sensor is designed in this paper. The COMSOL software is used to simulate the transmission field of optical sensing system. The responsiveness of symmetry optical path reflection type optical current sensor to Faraday effect can be obtained by the simulation study. The results show that the sensitivity of current sensor of symmetry optical path reflection type optical is 580 times higher than the sensitivity of traditional linear type optical current sensor. Finally the influence rule of measuring result error caused by sensing area positional deviation is analyzed. Further study about potential application of optical current sensor will proceed based on the optical current sensing system of symmetry optical path reflection type .

  19. Symptoms of depression and diabetes-specific emotional distress are associated with a negative appraisal of insulin therapy in insulin-naive patients with Type 2 diabetes mellitus. A study from the European Depression in Diabetes [EDID] Research Consortium

    NARCIS (Netherlands)

    Makine, C.; Karsidag, C.; Kadioglu, P.; Ilkova, H.; Karsidag, K.; Skovlund, S.E.; Snoek, F.J.; Pouwer, F.

    2009-01-01

    Aims: A meta-analysis concluded that depression is associated with poor glycaemic control in Type 2 diabetes (DM2). In DM2 patients with deteriorating glycaemic control, the initiation of insulin therapy is often postponed. The aim of the present study was to determine whether symptoms of depression

  20. Research progress of botulinum toxin type A in treatment of spastic cerebral palsy%A型肉毒毒素治疗痉挛型脑瘫的研究进展

    Institute of Scientific and Technical Information of China (English)

    刘春明(综述); 刘芸(审校)

    2015-01-01

    脑瘫是指出生前到出生后1个月内各种原因所引起的脑损伤或发育缺陷所致的运动障碍及姿势异常。小儿脑瘫临床上分为痉挛型,不随意运动型,共济失调型,肌张力低下型及混合型5种,其中,痉挛型占60%~70%,是造成儿童肢体残疾的最主要脑瘫类型。脑瘫一旦确诊多采用综合的治疗方法包括功能训练,物理疗法,中医针刺,按摩,药物治疗等。近年来,临床上开始广泛使用毒杆菌毒素 A(botuli-num toxin A,BTX-A)局部注射治疗痉挛型脑瘫儿童,大量临床研究结果显示该药安全、有效,但在治疗过程中应该严格掌握使用该药的适应证,禁忌证,而剂量的选择和靶肌的准确定位是影响治疗效果的关键因素。%Cerebral palsy refers to brain injury caused by various reasons from before birth to 1 month after birth or movement disorders and abnormal posture caused by brain developmental defects. Children cerebral palsy is divided into 5 kinds in the clinic:spastic type, dyskinetic type, ataxia type, muscle hypotonia type and mixed type. Among them, the spastic type accounts for 60% ~70% , and is the main type which causes children physical disabilities. Once diagnosed, the comprehensive treatment method is ap-plied, including functional training, physical therapy, acupuncture, massage, medicine treatment, and so on. In recent years, the lo-cal injection of botulinum toxin A is used for treating the children with spastic cerebral palsy. A large number of clinical studies show that the drug is safe and effective; however, in the course of treatment, it should strictly control the drug indications and contraindica-tions. Especially, the dosage choice and the accurate localization of target muscle is the key factor to influence the treatment effect.

  1. Research on the Different Surfaces of Aircraft Space Truss Type Weldment Manufacturing Technology%关于飞机空间异面桁架类焊接件制造技术的研究

    Institute of Scientific and Technical Information of China (English)

    李晓宁; 肖望东; 王声; 黄蓉; 张大均

    2016-01-01

    The winglet rack of a certain type of aircraft is as an example to present a typical spatial plane truss welding manufacturing method and way .Through the description of a certain type of aircraft wing pylon structure characteristic ,in-troduce the process of a certain type of aircraft wing pylons ,industry and trade dress design idea ,and how to use reverse measurement technology to resolve the difficulties in the process of development ,and finally achieve a certain type of aircraft wing pylons delivery and assembly .Its successful development provides the valuable experience for the manufacture of wel-ded assemblies of space plane truss structures ,which is of great reference value for the development of space plane truss type welding parts .%以某型机小翼挂架为例,研究了一种典型的空间异面桁架类焊接件制造方法与途径.通过对某型机小翼挂架结构特点的描述,详细介绍了某型机小翼挂架的工艺方法、工装设计思路,以及如何利用逆向测量技术解决研制过程中的难点,最终实现某型机小翼挂架的交付与装配.它的成功研制为空间异面类桁架结构焊组件的制造提供了宝贵的经验,对空间异面桁架类焊接件的研制具有借鉴与指导意义.

  2. 魅力型领导、下属的信任与团队创新绩效关系的研究%Research on the Relations of Charismatic - typed Leader, Trust of Subordinates and Performance of Team Innovation

    Institute of Scientific and Technical Information of China (English)

    张伟明; 夏洪胜

    2011-01-01

    通过结构方程模型的方法探讨魅力型领导、下属的信任与团队创新绩效三者之间的关系.研究结果发现:(1) 魅力型领导与团队创新绩效显著正相关;(2) 魅力型领导与下属的信任显著正相关;(3) 相比下属的认知信任,魅力型领导与下属的情感信任相关度更高;(4) 下属的信任对团队创新绩效显著正相关;(5) 下属的信任在魅力型领导与团队创新绩效之间起着完全中介的作用.%In this paper, we use structural equation modeling to examine the relations of charismatic -typed leader, trust of subordinates and performance of team innovation. The results showed: ( 1 ) charismatic - typed leader is significantly related to performance of team innovation; ( 2 ) charismatic - typed leader is significantly related to trust of subordinates; (3) charismatic- typed leader is more closely related to subordinates' emotional trust than to subordinates' cognitive trust; ( 4 ) trust of subordinates is significantly related to performance of team innovation; ( 5 ) subordinates' trust helps display mediating effects on the relationship between charismatic - typed leader and performance of team innovation.

  3. Research and Evaluation in Educational Television.

    Science.gov (United States)

    Mielke, Keith W.

    A fundamental distinction is made between basic research which seeks out new, generalizable knowledge, and administrative research which provides information useful to decision makers who have a task to perform. Attention is then given to four types of administrative research: background research, formative research, summative research, and policy…

  4. 7 CFR 1250.311 - Research.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 10 2010-01-01 2010-01-01 false Research. 1250.311 Section 1250.311 Agriculture... AND ORDERS; MISCELLANEOUS COMMODITIES), DEPARTMENT OF AGRICULTURE EGG RESEARCH AND PROMOTION Egg Research and Promotion Order Definitions § 1250.311 Research. Research means any type of research...

  5. Blood Type Game

    Science.gov (United States)

    ... Blood > Blood Donor Community > Games > Blood Type Game Blood Type Game This feature requires version 6 or later ... many points as possible by matching the appropriate blood type of a donor to the blood type of ...

  6. Facts about Type 2

    Medline Plus

    Full Text Available ... Text Size: A A A Listen En Español Facts About Type 2 Type 2 diabetes is the ... 2, In this section Diabetes Basics Type 2 Facts About Type 2 Recently Diagnosed Treatment and Care ...

  7. Fuel safety research 2001

    Energy Technology Data Exchange (ETDEWEB)

    Uetsuka, Hiroshi (ed.) [Japan Atomic Energy Research Inst., Tokai, Ibaraki (Japan). Tokai Research Establishment

    2002-11-01

    The Fuel Safety Research Laboratory is in charge of research activity which covers almost research items related to fuel safety of water reactor in JAERI. Various types of experimental and analytical researches are being conducted by using some unique facilities such as the Nuclear Safety Research Reactor (NSRR), the Japan Material Testing Reactor (JMTR), the Japan Research Reactor 3 (JRR-3) and the Reactor Fuel Examination Facility (RFEF) of JAERI. The research to confirm the safety of high burn-up fuel and MOX fuel under accident conditions is the most important item among them. The laboratory consists of following five research groups corresponding to each research fields; Research group of fuel behavior under the reactivity initiated accident conditions (RIA group). Research group of fuel behavior under the loss-of-coolant accident conditions (LOCA group). Research group of fuel behavior under the normal operation conditions (JMTR/BOCA group). Research group of fuel behavior analysis (FEMAXI group). Research group of radionuclides release and transport behavior from irradiated fuel under severe accident conditions (VEGA group). The research conducted in the year 2001 produced many important data and information. They are, for example, the fuel behavior data under BWR power oscillation conditions in the NSRR, the data on failure-bearing capability of hydrided cladding under LOCA conditions and the FP release data at very high temperature in steam which simulate the reactor core condition during severe accidents. This report summarizes the outline of research activities and major outcomes of the research executed in 2001 in the Fuel Safety Research Laboratory. (author)

  8. The main types of biochar and their properties and expectative researches%生物炭主要类型、理化性质及其研究展望

    Institute of Scientific and Technical Information of China (English)

    袁帅; 赵立欣; 孟海波; 沈玉君

    2016-01-01

    researches should be considered in the future. Firstly, the differences in beneficial effects of biochar related manufacture parameters and raw materials should be systemically studied and a database should be setup accordingly; the suitable type of biochar should be made clear according to the expected target and the soil properties, to achieve the highest profit of biochar. More work is also needed for the selection and combination of biochar from different material sources, so to produce multiple functional products to meet the requirement of practical use.

  9. Ⅰ型Stickler综合征家系临床和基因突变研究%Clinical and genetic research in a Chinese family with Stickler syndrome type 1

    Institute of Scientific and Technical Information of China (English)

    李凤荣; 周崎; 李惠; 睢瑞芳

    2012-01-01

    背景 Stickler综合征是一种遗传性结缔组织病,主要以眼部、关节、口面部及听力损伤为特征.确定Stickler综合征的基因突变位点能够为该综合征的基因诊断和治疗提供依据. 目的 研究一个Ⅰ型Stickler综合征家系的临床特征并确定致病基因突变. 方法 对一个患Ⅰ型Stickler综合征的家系进行临床研究和系谱分析.采集Stickler综合征家系中3例患者和6位表型正常者的外周血标本,采用PCR法扩增COL2A1基因的全部外显子及其侧翼,对扩增产物进行直接测序,结果与Genbank中相应序列进行比对.同时检测100位无亲缘关系的正常人外周血标本进行对照. 结果 该家系共4代11位成员,2位成员去世,其中包括1例患病者.现存的9位成员中共3例患者,调查显示该家系符合常染色显性遗传方式.3例患者的临床特点包括高度近视、膜型玻璃体异常及面中部扁平、短鼻、腭裂等,符合Ⅰ型Stickler综合征的临床诊断.COL2A1基因突变筛查结果显示,该家系中3例患者COL2A1基因内含子12的第一个碱基发生了单个碱基缺失(IVS12+1G del)的杂合性剪接位点突变,核苷酸序列分析结果证实该突变致提前形成终止密码子,形成一种包括306个氨基酸在内的截短蛋白,导致该基因的功能异常,而家系中表型正常者及无亲缘关系的正常对照者均未发现该基因突变. 结论 本研究确定了一个Ⅰ型Stickler家系,并在该家系确定了一个新的COL2A1基因突变,这是中国首次报道Stickler综合征家系的基因突变.%Background Stickler syndrome is a genetic connective tissue disorder that affects the ocular,skeletal,orofacial and auditory systems.To determine the gene mutation loci can offer a basis for genetic diagnosis and management of Stickler syndrome.Objective The aim of this study was to research the clinical characteristics of a pedigree with Stickler syndrome and identify the disease

  10. Clinical research informatics

    CERN Document Server

    Richesson, Rachel L

    2012-01-01

    This book provides foundational coverage of key areas, concepts, constructs, and approaches of medical informatics as it applies to clinical research activities, in both current settings and in light of emerging policies. The field of clinical research is fully characterized (in terms of study design and overarching business processes), and there is emphasis on information management aspects and informatics implications (including needed activities) within various clinical research environments. The purpose of the book is to provide an overview of clinical research (types), activities, and are

  11. Clinical research on the different placenta previa type and bleeding in the pregnancy%不同前置胎盘类型与孕期出血状况临床研究

    Institute of Scientific and Technical Information of China (English)

    李富萍; 赵有红; 脱淑梅

    2012-01-01

    Objective To investigate the risk factors lead to the occurrence of placenta prevla and antepartum hemorrhage between different types of placenta previa. Methods To comparatively analyze 198 cases of placenta previa patients and 198 patients in the control group on risk factors for bleeding before 34 weeks and compare different types of placenta obstetric risk factors and the incidence of ari1.epar1.uiri haemorrhage. Results There were significantly differences in obstetric risk factors between placenta previa group and control group (P < 0.05), the difference was no statistically significant in the type of placenta previa (P > 0.05). The incidence of anteparlum haemorrhage in the type of placenta previa showed no significant difference (P > 0.05). Conclusion Obstetric risk factors is related to placenta previa, but is not related to the types of placenta previa; the type of placenta previa is not associated with antepartum bleeding.%目的 探讨导致前置胎盘发生的高危因素及不同类型前置胎盘产前出血状况.方法 采用回顾性病例对照研究设计,对比分析198例前置胎盘病例组和198例对照组有关危险因素,并比较不同胎盘类型的产科危险因素及孕34周前出血状况.结果 产科高危因素在前置胎盘组与对照组之间比较差异有统计学意义(P0.05);不同前置胎盘类型在孕34周前发生产前出血几率比较,差异无统计学意义(P>0.05).结论 产科高危因素与前置胎盘的形成有关,但与前置胎盘类型无关;前置胎盘类型并不能预测产前是否能发生突破性大出血.

  12. Facts about Type 2

    Medline Plus

    Full Text Available ... Alert Day Diabetes Basics Home Symptoms Diagnosis America's Diabetes Challenge Type 1 Type 2 Facts About Type 2 Enroll in ... Where Do I Begin With Type2? Living With Type 1 Diabetes Enroll in the Living WIth Type 2 Diabetes ...

  13. Glucagon and type 2 diabetes

    DEFF Research Database (Denmark)

    Lund, Asger; Bagger, Jonatan I; Christensen, Mikkel

    2014-01-01

    In normal physiology, glucagon from pancreatic alpha cells plays an important role in maintaining glucose homeostasis via its regulatory effect on hepatic glucose production. Patients with type 2 diabetes suffer from fasting and postprandial hyperglucagonemia, which stimulate hepatic glucose...... production and, thus, contribute to the hyperglycemia characterizing these patients. Although this has been known for years, research focusing on alpha cell (patho)physiology has historically been dwarfed by research on beta cells and insulin. Today the mechanisms behind type 2 diabetic hyperglucagonemia...... or antagonization of the glucagon receptor constitutes potentially effective treatment strategies for patients with type 2 diabetes. In this review, we focus on the regulation of glucagon secretion by the incretin hormones glucagon-like peptide-1 (GLP-1) and GIP. Furthermore, potential advantages and limitations...

  14. 树脂浇注式干式变压器绕组温度场研究%Research on Temperature Field of Winding in Cast-Resin Dry-Type Transformer

    Institute of Scientific and Technical Information of China (English)

    朱恒宣; 王秀春; 刘汝江

    2013-01-01

    介绍了树脂浇注干式变压器绕组结构及其物理模型假设条件,建立了传热与流动数学模型,完成了树脂浇注式变压器绕组温度场的计算,给出了计算结果,并与试验结果进行了对比.%The winding structure and model condition of the cast-resin dry-type transformer are introduced. The mathematic model of heat transfer and oil flow is established. The temperature field of winding in cast-resin dry-type transformer is calculated. The calculated results are presented and compared with tested ones.

  15. PFGE molecular typing research on Enterobacter Sakazakii isolates during the process of formula milk powder manufacture%配方奶粉加工过程阪崎克罗诺杆菌PFGE分子分型研究

    Institute of Scientific and Technical Information of China (English)

    周蒂; 颜巧红; 郝东海; 王新苗; 陈建才; 梅玲玲

    2014-01-01

    Objective To analyze pulse-field gel electrophoresis (PFGE) type of Enterobacter Sakazakii isolated during the process of formula milk powder production and monitoring.Methods Enterobacter Sakazakii isolates were digested with enzyme Xba I,fingerprintings were established with PFGE,and clustered and analyzed with BioNumerics V 6.6 software.Results Total 29 types of genome fingerprintings were detected from 46 Enterobacter Sakazakii isolates.The homology of other strains were above 60% except type PTP29.Type PTP3 were observed among strains isolated from 1 batch semi-manufactured product and 3 batches of product.Strains from Type PTP7 and PTP8 were isolated from raw milk powder and concentrated whey protein powder respectively.Strains from Type PTP18 were isolated from milk powder,powder particles,the wall of producing department,and conveyor.Strains from Type PTP27 were isolated from milk powder,semi-manufactured products and α-whey protein.Conclusion PFGE was demonstratcd to be efficient for E.Sakazakii molecular typing.Meanwhile,E.Sakazakii is prevalent regionally.Raw material and produce environments were illuminated to be main sources of contamination.%目的 对配方奶粉加工控制过程中分离的阪崎克罗诺杆菌开展PFGE图谱研究.方法 用XbaⅠ酶切割,脉冲场凝胶电泳技术建立PFGE指纹图谱,BioNumerics V 6.6软件进行聚类分析.结果 46株阪崎克罗诺杆菌共形成了29种PFGE基因指纹图谱.除图谱PT29外,其余菌株的同源性>60%.1件半成品、3件不同批次的产品分离的菌株图谱一致(图谱PTP3).图谱PTP7、PTP8的菌株分别分离自原料奶粉和浓缩乳清蛋白粉.图谱PTP18菌株分离自成品、筛粉、墙壁、设备传送带样品.图谱PTP27菌株分离自成品、混料(半成品)和α-乳白蛋白.结论 PFGE技术对阪崎克罗诺杆菌具有很好的分型效果.阪崎克罗诺杆菌存在局部流行现象,原料带菌、加工环境是婴儿配方粉阪崎克罗诺杆菌污染的主要途径.

  16. Maximal regularity via reverse Hölder inequalities for elliptic systems of n-Laplace type involving measures hospitality and the Taft Research Fund for the financial support. The present work is part of the ESF Programme GLOBAL.-->

    Science.gov (United States)

    Kilpeläinen, Tero; Shanmugalingam, Nageswari; Zhong, Xiao

    2008-04-01

    In this note, we consider the regularity of solutions of the nonlinear elliptic systems of n-Laplacian type involving measures, and prove that the gradients of the solutions are in the weak Lebesgue space L n,∞. We also obtain the a priori global and local estimates for the L n,∞-norm of the gradients of the solutions without using BMO-estimates. The proofs are based on a new lemma on the higher integrability of functions.

  17. HE EXPERIMENTAL RESEARCH ON NOVEL DC S/N TRANSITION HYBRID TYPE OF HTSCFCL%一种新型直流混合型HTSCFCL的实验研究

    Institute of Scientific and Technical Information of China (English)

    张晚英; 张绪红; 赵伟明; 周有庆; 朱英浩

    2011-01-01

    Base on studying of the working principle of hybrid type dc high temperature superconducting fault current limiter and dc S/N transition rectifier bridge type high temperature superconducting fault current limiter, a novel single-phase hybrid type dc high temperature superconducting fault current limiter is proposed. Experiments of various short-circuit fault by the novel single-phase hybrid type dc high temperature superconducting fault current limiter have been performed, the experimental results show the good limiting capability of the device, the new design method by MATLAB simulation that we put forward in this paper is a effective approach for the accurate design parameters and its satisfactory limiting-current performances. The device is of great benefit to limit fault current and improve transient stability of power system.%在研究直流混合型高温超导限流器和失超型桥式高温超导限流器原理的基础上,提出了一种新型单相直流混合型高温超导限流器.实验表明该限流器有较好的限流能力,MATLAB仿真结果也表明该限流器模型设计参数准确,限流效果明显.说明新型直流混合型高温超导限流器对限制短路电流和提高系统的稳定运行具有十分重要的意义.

  18. Comparative research on Cambrian Burgess Shale-type soft-bodied fossil biotas in South China%华南布尔吉斯页岩型软躯体化石生物群对比研究

    Institute of Scientific and Technical Information of China (English)

    段艳红; 韩健; 张志飞; 刘建妮

    2012-01-01

    Aim To combing from the Burgess Shale-type fossil biotas in South China at the sight of horizon, biological composition and sedimentary environment. Methods Ten Burgess Shale-type soft-bodied fossil biotas in South China are investigated by comparing the geological settings, biological composition and their substrates. Results Except for the Yanjiahe biota, the other nine Cambrian Burgess Shale-type soft-bodied fossil biotas in South China represent a series of closely-related biological communities lived in muddy-sandy substrates which show gradually transitions in biological composition in time-space distributions. Conclusion The Burgess Shale-type fossil biota in South China should have a wider distribution during the Middle-Late Cambrian.%目的 梳理华南布尔吉斯页岩型软躯体化石生物群的产出层位、生物面貌和沉积环境.方法 对10个华南布尔吉斯页岩型软躯体化石生物群进行对比研究.结果 除了岩家河生物群之外的9个布尔吉斯页岩型生物群代表了一系列生活在泥砂质基底的、从时空分布上逐渐过渡的具有高度相关性的生物群落.结论 布尔吉斯页岩型化石生物群在中晚寒武世应该会有更大规模的分布.

  19. 重型立式车床工作台开式静压导轨设计研究%Research on the Design of Open Type Hydrostatic Guideway on the Heavy Duty Vertical Lathe WEork Table

    Institute of Scientific and Technical Information of China (English)

    王晓刚; 闫克泉; 王一岭; 梁斌顺

    2012-01-01

    设计一种重型立车工作台回转用导轨,采用开式静压方式,满足立车工作台回转和承重要求。%The paper designed one kind of guideway adopt open hydrostatic type used for the work table of heavy duty vertical lathe so that it meet the requirements of rotation and bearing of vertical lathe.

  20. 遗传算法在多类型的车辆人员排班系统中的应用与研究%The Research and Application of Multiple Types of Vehicles and Personnel Scheduling System with Genetic Algorithm

    Institute of Scientific and Technical Information of China (English)

    梁剑波; 柴群

    2014-01-01

    The main problem of the scheduling of the public transport vehicles and personnel is that, at a given time and number of vehicle cases, minimal cost cover all of the trips. With formerly was aimed at the single type of vehicles scheduling differently, this article mainly provides the support of multiple types of vehicles and personnel scheduling. Firstly, it use efficient Auction algo⁃rithms to obtain the least costly group trips, and assigned vehicle types according to the groupings;then use a random search of ge⁃netic algorithm to obtain the optimal solution. Experimental results show that it has very good results that the genetic algorithm is applied to multiple types of public vehicles and personnel scheduling.%公交车辆人员排班的主要问题就是在给定时间点和车次数的情况下,以最小代价覆盖所有的车次。与以往都是针对单类型车辆的人员排班不同,该文主要提供对多类型的车辆人员排班的支持。首先利用高效的Auction算法获取代价最小的车次分组并根据分组情况分配车辆的营运类型;然后使用遗传算法进行随机化搜索以获得最优解。实验表明,遗传算法应用于多类型的公交车辆人员排班具有很好的效果。