Large deep neural networks for MS lesion segmentation

Science.gov (United States)

Prieto, Juan C.; Cavallari, Michele; Palotai, Miklos; Morales Pinzon, Alfredo; Egorova, Svetlana; Styner, Martin; Guttmann, Charles R. G.

2017-02-01

Multiple sclerosis (MS) is a multi-factorial autoimmune disorder, characterized by spatial and temporal dissemination of brain lesions that are visible in T2-weighted and Proton Density (PD) MRI. Assessment of lesion burden and is useful for monitoring the course of the disease, and assessing correlates of clinical outcomes. Although there are established semi-automated methods to measure lesion volume, most of them require human interaction and editing, which are time consuming and limits the ability to analyze large sets of data with high accuracy. The primary objective of this work is to improve existing segmentation algorithms and accelerate the time consuming operation of identifying and validating MS lesions. In this paper, a Deep Neural Network for MS Lesion Segmentation is implemented. The MS lesion samples are extracted from the Partners Comprehensive Longitudinal Investigation of Multiple Sclerosis (CLIMB) study. A set of 900 subjects with T2, PD and a manually corrected label map images were used to train a Deep Neural Network and identify MS lesions. Initial tests using this network achieved a 90% accuracy rate. A secondary goal was to enable this data repository for big data analysis by using this algorithm to segment the remaining cases available in the CLIMB repository.

Statistical Characterization of the Chandra Source Catalog

Science.gov (United States)

Primini, Francis A.; Houck, John C.; Davis, John E.; Nowak, Michael A.; Evans, Ian N.; Glotfelty, Kenny J.; Anderson, Craig S.; Bonaventura, Nina R.; Chen, Judy C.; Doe, Stephen M.; Evans, Janet D.; Fabbiano, Giuseppina; Galle, Elizabeth C.; Gibbs, Danny G.; Grier, John D.; Hain, Roger M.; Hall, Diane M.; Harbo, Peter N.; He, Xiangqun Helen; Karovska, Margarita; Kashyap, Vinay L.; Lauer, Jennifer; McCollough, Michael L.; McDowell, Jonathan C.; Miller, Joseph B.; Mitschang, Arik W.; Morgan, Douglas L.; Mossman, Amy E.; Nichols, Joy S.; Plummer, David A.; Refsdal, Brian L.; Rots, Arnold H.; Siemiginowska, Aneta; Sundheim, Beth A.; Tibbetts, Michael S.; Van Stone, David W.; Winkelman, Sherry L.; Zografou, Panagoula

2011-06-01

The first release of the Chandra Source Catalog (CSC) contains ~95,000 X-ray sources in a total area of 0.75% of the entire sky, using data from ~3900 separate ACIS observations of a multitude of different types of X-ray sources. In order to maximize the scientific benefit of such a large, heterogeneous data set, careful characterization of the statistical properties of the catalog, i.e., completeness, sensitivity, false source rate, and accuracy of source properties, is required. Characterization efforts of other large Chandra catalogs, such as the ChaMP Point Source Catalog or the 2 Mega-second Deep Field Surveys, while informative, cannot serve this purpose, since the CSC analysis procedures are significantly different and the range of allowable data is much less restrictive. We describe here the characterization process for the CSC. This process includes both a comparison of real CSC results with those of other, deeper Chandra catalogs of the same targets and extensive simulations of blank-sky and point-source populations.

Deep 20-GHz survey of the Chandra Deep Field South and SDSS Stripe 82: source catalogue and spectral properties

Science.gov (United States)

Franzen, Thomas M. O.; Sadler, Elaine M.; Chhetri, Rajan; Ekers, Ronald D.; Mahony, Elizabeth K.; Murphy, Tara; Norris, Ray P.; Waldram, Elizabeth M.; Whittam, Imogen H.

2014-04-01

We present a source catalogue and first results from a deep, blind radio survey carried out at 20 GHz with the Australia Telescope Compact Array, with follow-up observations at 5.5, 9 and 18 GHz. The Australia Telescope 20 GHz (AT20G) deep pilot survey covers a total area of 5 deg2 in the Chandra Deep Field South and in Stripe 82 of the Sloan Digital Sky Survey. We estimate the survey to be 90 per cent complete above 2.5 mJy. Of the 85 sources detected, 55 per cent have steep spectra (α _{1.4}^{20} law spectra between 1.4 and 18 GHz, while the spectral indices of the flat- or inverted-spectrum sources tend to steepen with frequency. Among the 18 inverted-spectrum (α _{1.4}^{20} ≥ 0.0) sources, 10 have clearly defined peaks in their spectra with α _{1.4}^{5.5} > 0.15 and α 9^{18} Cambridge and Tenth Cambridge surveys: there is a shift towards a steeper-spectrum population when going from ˜1 Jy to ˜5 mJy, which is followed by a shift back towards a flatter-spectrum population below ˜5 mJy. The 5-GHz source-count model by Jackson & Wall, which only includes contributions from FRI and FRII sources, and star-forming galaxies, does not reproduce the observed flattening of the flat-spectrum counts below ˜5 mJy. It is therefore possible that another population of sources is contributing to this effect.

DEEP CHANDRA OBSERVATIONS OF NGC 1404: CLUSTER PLASMA PHYSICS REVEALED BY AN INFALLING EARLY-TYPE GALAXY

Energy Technology Data Exchange (ETDEWEB)

Su, Yuanyuan; Kraft, Ralph P.; Nulsen, Paul; Forman, William R.; Randall, Scott W.; Jones, Christine; Machacek, Marie E. [Harvard-Smithsonian Center for Astrophysics, 60 Garden Street, Cambridge, MA 02138 (United States); Roediger, Elke [E.A. Milne Centre for Astrophysics, Department of Physics and Mathematics, University of Hull, Hull, HU6 7RX (United Kingdom); Churazov, Eugene, E-mail: yuanyuan.su@cfa.harvard.edu [Max Planck Institute for Astrophysics, Karl-Schwarzschild-Str. 1, D-85741, Garching (Germany)

2017-01-01

The intracluster medium (ICM), as a magnetized and highly ionized fluid, provides an ideal laboratory to study plasma physics under extreme conditions that cannot be achieved on Earth. NGC 1404 is a bright elliptical galaxy that is being gas stripped as it falls through the ICM of the Fornax Cluster. We use the new Chandra X-ray observations of NGC 1404 to study ICM microphysics. The interstellar medium of NGC 1404 is characterized by a sharp leading edge, 8 kpc from the Galaxy center, and a short downstream gaseous tail. Contact discontinuities are resolved on unprecedented spatial scales (0.″5 = 45 pc) due to the combination of the proximity of NGC 1404, the superb spatial resolution of Chandra , and the very deep (670 ks) exposure. At the leading edge, we observe sub-kiloparsec-scale eddies generated by Kelvin–Helmholtz instability (KHI) and put an upper limit of 5% Spitzer on the isotropic viscosity of the hot cluster plasma. We also observe mixing between the hot cluster gas and the cooler galaxy gas in the downstream stripped tail, which provides further evidence of a low viscosity plasma. The assumed ordered magnetic fields in the ICM ought to be smaller than 5 μ G to allow KHI to develop. The lack of an evident magnetic draping layer just outside the contact edge is consistent with such an upper limit.

STATISTICAL CHARACTERIZATION OF THE CHANDRA SOURCE CATALOG

International Nuclear Information System (INIS)

Primini, Francis A.; Evans, Ian N.; Glotfelty, Kenny J.; Anderson, Craig S.; Bonaventura, Nina R.; Chen, Judy C.; Doe, Stephen M.; Evans, Janet D.; Fabbiano, Giuseppina; Galle, Elizabeth C.; Gibbs, Danny G.; Grier, John D.; Hain, Roger M.; Harbo, Peter N.; He Xiangqun; Karovska, Margarita; Houck, John C.; Davis, John E.; Nowak, Michael A.; Hall, Diane M.

2011-01-01

The first release of the Chandra Source Catalog (CSC) contains ∼95,000 X-ray sources in a total area of 0.75% of the entire sky, using data from ∼3900 separate ACIS observations of a multitude of different types of X-ray sources. In order to maximize the scientific benefit of such a large, heterogeneous data set, careful characterization of the statistical properties of the catalog, i.e., completeness, sensitivity, false source rate, and accuracy of source properties, is required. Characterization efforts of other large Chandra catalogs, such as the ChaMP Point Source Catalog or the 2 Mega-second Deep Field Surveys, while informative, cannot serve this purpose, since the CSC analysis procedures are significantly different and the range of allowable data is much less restrictive. We describe here the characterization process for the CSC. This process includes both a comparison of real CSC results with those of other, deeper Chandra catalogs of the same targets and extensive simulations of blank-sky and point-source populations.

Stripped Elliptical Galaxies as Probes of ICM Physics. III. Deep Chandra Observations of NGC 4552: Measuring the Viscosity of the Intracluster Medium

Energy Technology Data Exchange (ETDEWEB)

Kraft, R. P.; Roediger, E.; Machacek, M.; Forman, W. R.; Nulsen, P. E. J.; Jones, C.; Randall, S.; Su, Y. [Harvard/Smithsonian Center for Astrophysics, 60 Garden Street, Cambridge, MA 02138 (United States); Churazov, E. [MPI für Astrophysik, Karl-Schwarzschild-Str. 1, Garching D-85741 (Germany); Sheardown, A., E-mail: rkraft@cfa.harvard.edu [E. A. Milne Center for Astrophysics, Department of Physics and Mathematics, University of Hull, Hull, HU6 7RX (United Kingdom)

2017-10-10

We present results from a deep (200 ks) Chandra observation of the early-type galaxy NGC 4552 (M89), which is falling into the Virgo cluster. Previous shallower X-ray observations of this galaxy showed a remnant gas core, a tail to the South of the galaxy, and twin “horns” attached to the northern edge of the gas core. In our deeper data, we detect a diffuse, low surface brightness extension to the previously known tail, and measure the temperature structure within the tail. We combine the deep Chandra data with archival XMM-Newton observations to put a strong upper limit on the diffuse emission of the tail out to a large distance (10× the radius of the remnant core) from the galaxy center. In our two previous papers, we presented the results of hydrodynamical simulations of ram pressure stripping specifically for M89 falling into the Virgo cluster and investigated the effect of intracluster medium (ICM) viscosity. In this paper, we compare our deep data with our specifically tailored simulations and conclude that the observed morphology of the stripped tail in NGC 4552 is most similar to the inviscid models. We conclude that, to the extent the transport processes can be simply modeled as a hydrodynamic viscosity, the ICM viscosity is negligible. More generally, any micro-scale description of the transport processes in the high- β plasma of the cluster ICM must be consistent with the efficient mixing observed in the stripped tail on macroscopic scales.

The Chandra Deep Field South as a test case for Global Multi Conjugate Adaptive Optics

Science.gov (United States)

Portaluri, E.; Viotto, V.; Ragazzoni, R.; Gullieuszik, M.; Bergomi, M.; Greggio, D.; Biondi, F.; Dima, M.; Magrin, D.; Farinato, J.

2017-04-01

The era of the next generation of giant telescopes requires not only the advent of new technologies but also the development of novel methods, in order to exploit fully the extraordinary potential they are built for. Global Multi Conjugate Adaptive Optics (GMCAO) pursues this approach, with the goal of achieving good performance over a field of view of a few arcmin and an increase in sky coverage. In this article, we show the gain offered by this technique to an astrophysical application, such as the photometric survey strategy applied to the Chandra Deep Field South as a case study. We simulated a close-to-real observation of a 500 × 500 arcsec2 extragalactic deep field with a 40-m class telescope that implements GMCAO. We analysed mock K-band images of 6000 high-redshift (up to z = 2.75) galaxies therein as if they were real to recover the initial input parameters. We attained 94.5 per cent completeness for source detection with SEXTRACTOR. We also measured the morphological parameters of all the sources with the two-dimensional fitting tools GALFIT. The agreement we found between recovered and intrinsic parameters demonstrates GMCAO as a reliable approach to assist extremely large telescope (ELT) observations of extragalactic interest.

Chandra Maps Vital Elements From Supernova

Science.gov (United States)

1999-12-01

A team of astronomers led by Dr. John Hughes of Rutgers University in Piscataway, NJ has used observations from NASA's orbital Chandra X-ray Observatory to make an important new discovery that sheds light on how silicon, iron, and other elements were produced in supernova explosions. An X-ray image of Cassiopeia A (Cas A), the remnant of an exploded star, reveals gaseous clumps of silicon, sulfur, and iron expelled from deep in the interior of the star. The findings appear online in the Astrophysical Journal Letters at http://www.journals.uchicago.edu/ and are slated for print publication on Jan. 10, 2000. Authors of the paper, "Nucleosynthesis and Mixing in Cassiopeia A", are Hughes, Rutgers graduate student Cara Rakowski, Dr. David Burrows of the Pennsylvania State University, University Park, PA and Dr. Patrick Slane of the Harvard-Smithsonian Center for Astrophysics, Cambridge, MA. According to Hughes, one of the most profound accomplishments of twentieth century astronomy is the realization that nearly all of the elements other than hydrogen and helium were created in the interiors of stars. "During their lives, stars are factories that take the simplest element, hydrogen, and convert it into heavier ones," he said. "After consuming all the hydrogen in their cores, stars begin to evolve rapidly, until they finally run out of fuel and begin to collapse. In stars ten times or so more massive than our Sun, the central parts of the collapsing star may form a neutron star or a black hole, while the rest of the star is blown apart in a tremendous supernova explosion." Supernovae are rare, occurring only once every 50 years or so in a galaxy like our own. "When I first looked at the Chandra image of Cas A, I was amazed by the clarity and definition," said Hughes. "The image was much sharper than any previous one and I could immediately see lots of new details." Equal in significance to the image clarity is the potential the Chandra data held for measuring the

STAR FORMATION IN THE CHANDRA DEEP FIELD SOUTH: OBSERVATIONS CONFRONT SIMULATIONS

International Nuclear Information System (INIS)

Damen, Maaike; Franx, Marijn; Foerster Schreiber, Natascha M.; Labbe, Ivo; Toft, Sune; Van Dokkum, Pieter G.; Wuyts, Stijn

2009-01-01

We investigate the star formation history of the universe using FIREWORKS, a multiwavelength survey of the Chandra Deep Field South. We study the evolution of the specific star formation rate (sSFR) with redshift in different mass bins from z = 0 to z ∼ 3. We find that the sSFR increases with redshift for all masses. The logarithmic increase of the sSFR with redshift is nearly independent of mass, but this cannot yet be verified at the lowest-mass bins at z>0.8, due to incompleteness. We convert the sSFRs to a dimensionless growth rate to facilitate a comparison with a semianalytic galaxy formation model that was implemented on the Millennium Simulation. The model predicts that the growth rates and sSFRs increase similarly with redshift for all masses, consistent with the observations. However, we find that for all masses, the inferred observed growth rates increase more rapidly with redshift than the model predictions. We discuss several possible causes for this discrepancy, ranging from field-to-field variance, conversions to SFR, and shape of the initial mass function. We find that none of these can solve the discrepancy completely. We conclude that the models need to be adapted to produce the steep increase in growth rate between redshift z = 0 and z = 1.

A DEEP CHANDRA ACIS STUDY OF NGC 4151. III. THE LINE EMISSION AND SPECTRAL ANALYSIS OF THE IONIZATION CONE

International Nuclear Information System (INIS)

Wang, Junfeng; Fabbiano, Giuseppina; Elvis, Martin; Risaliti, Guido; Karovska, Margarita; Zezas, Andreas; Mundell, Carole G.; Dumas, Gaelle; Schinnerer, Eva

2011-01-01

This paper is the third in a series in which we present deep Chandra ACIS-S imaging spectroscopy of the Seyfert 1 galaxy NGC 4151, devoted to study its complex circumnuclear X-ray emission. Emission features in the soft X-ray spectrum of the bright extended emission (L 0.3-2 k eV ∼ 10 40 erg s –1 ) at r > 130 pc (2'') are consistent with blended brighter O VII, O VIII, and Ne IX lines seen in the Chandra HETGS and XMM-Newton RGS spectra below 2 keV. We construct emission line images of these features and find good morphological correlations with the narrow-line region clouds mapped in [O III] λ5007. Self-consistent photoionization models provide good descriptions of the spectra of the large-scale emission, as well as resolved structures, supporting the dominant role of nuclear photoionization, although displacement of optical and X-ray features implies a more complex medium. Collisionally ionized emission is estimated to be ∼ ☉ yr –1 at 130 pc and the kinematic power of the ionized outflow is 1.7 × 10 41 erg s –1 , approximately 0.3% of the bolometric luminosity of the active nucleus in NGC 4151.

CHEERS Results from NGC 3393. II. Investigating the Extended Narrow-line Region Using Deep Chandra Observations and Hubble Space Telescope Narrow-line Imaging

Energy Technology Data Exchange (ETDEWEB)

Maksym, W. Peter; Fabbiano, Giuseppina; Elvis, Martin; Karovska, Margarita; Paggi, Alessandro; Raymond, John [Harvard-Smithsonian Center for Astrophysics, 60 Garden St., Cambridge, MA 02138 (United States); Wang, Junfeng [Department of Astronomy, Physics Building, Xiamen University Xiamen, Fujian, 361005 (China); Storchi-Bergmann, Thaisa, E-mail: walter.maksym@cfa.harvard.edu [Departamento de Astronomia, Universidade Federal do Rio Grande do Sul, IF, CP 15051, 91501-970 Porto Alegre, RS (Brazil)

2017-07-20

The CHandra Extended Emission Line Region Survey (CHEERS) is an X-ray study of nearby active galactic nuclei (AGNs) designed to take full advantage of Chandra 's unique angular resolution by spatially resolving feedback signatures and effects. In the second paper of a series on CHEERS target NGC 3393, we examine deep high-resolution Chandra images and compare them with Hubble Space Telescope narrow-line images of [O iii], [S ii], and H α , as well as previously unpublished mid-ultraviolet (MUV) images. The X-rays provide unprecedented evidence that the S-shaped arms that envelope the nuclear radio outflows extend only ≲0.″2 (≲50 pc) across. The high-resolution multiwavelength data suggest that the extended narrow-line region is a complex multiphase structure in the circumnuclear interstellar medium (ISM). Its ionization structure is highly stratified with respect to outflow-driven bubbles in the bicone and varies dramatically on scales of ∼10 pc. Multiple findings show likely contributions from shocks to the feedback in regions where radio outflows from the AGN most directly influence the ISM. These findings include H α evidence for gas compression and extended MUV emission and are in agreement with existing STIS kinematics. Extended filamentary structure in the X-rays and optical suggests the presence of an undetected plasma component, whose existence could be tested with deeper radio observations.

CHEERS Results from NGC 3393. II. Investigating the Extended Narrow-line Region Using Deep Chandra Observations and Hubble Space Telescope Narrow-line Imaging

Science.gov (United States)

Maksym, W. Peter; Fabbiano, Giuseppina; Elvis, Martin; Karovska, Margarita; Paggi, Alessandro; Raymond, John; Wang, Junfeng; Storchi-Bergmann, Thaisa

2017-07-01

The CHandra Extended Emission Line Region Survey (CHEERS) is an X-ray study of nearby active galactic nuclei (AGNs) designed to take full advantage of Chandra's unique angular resolution by spatially resolving feedback signatures and effects. In the second paper of a series on CHEERS target NGC 3393, we examine deep high-resolution Chandra images and compare them with Hubble Space Telescope narrow-line images of [O III], [S II], and Hα, as well as previously unpublished mid-ultraviolet (MUV) images. The X-rays provide unprecedented evidence that the S-shaped arms that envelope the nuclear radio outflows extend only ≲0.″2 (≲50 pc) across. The high-resolution multiwavelength data suggest that the extended narrow-line region is a complex multiphase structure in the circumnuclear interstellar medium (ISM). Its ionization structure is highly stratified with respect to outflow-driven bubbles in the bicone and varies dramatically on scales of ˜10 pc. Multiple findings show likely contributions from shocks to the feedback in regions where radio outflows from the AGN most directly influence the ISM. These findings include Hα evidence for gas compression and extended MUV emission and are in agreement with existing STIS kinematics. Extended filamentary structure in the X-rays and optical suggests the presence of an undetected plasma component, whose existence could be tested with deeper radio observations.

CHEERS Results from NGC 3393. II. Investigating the Extended Narrow-line Region Using Deep Chandra Observations and Hubble Space Telescope Narrow-line Imaging

International Nuclear Information System (INIS)

Maksym, W. Peter; Fabbiano, Giuseppina; Elvis, Martin; Karovska, Margarita; Paggi, Alessandro; Raymond, John; Wang, Junfeng; Storchi-Bergmann, Thaisa

2017-01-01

The CHandra Extended Emission Line Region Survey (CHEERS) is an X-ray study of nearby active galactic nuclei (AGNs) designed to take full advantage of Chandra 's unique angular resolution by spatially resolving feedback signatures and effects. In the second paper of a series on CHEERS target NGC 3393, we examine deep high-resolution Chandra images and compare them with Hubble Space Telescope narrow-line images of [O iii], [S ii], and H α , as well as previously unpublished mid-ultraviolet (MUV) images. The X-rays provide unprecedented evidence that the S-shaped arms that envelope the nuclear radio outflows extend only ≲0.″2 (≲50 pc) across. The high-resolution multiwavelength data suggest that the extended narrow-line region is a complex multiphase structure in the circumnuclear interstellar medium (ISM). Its ionization structure is highly stratified with respect to outflow-driven bubbles in the bicone and varies dramatically on scales of ∼10 pc. Multiple findings show likely contributions from shocks to the feedback in regions where radio outflows from the AGN most directly influence the ISM. These findings include H α evidence for gas compression and extended MUV emission and are in agreement with existing STIS kinematics. Extended filamentary structure in the X-rays and optical suggests the presence of an undetected plasma component, whose existence could be tested with deeper radio observations.

THE TAIWAN ECDFS NEAR-INFRARED SURVEY: ULTRA-DEEP J AND K{sub S} IMAGING IN THE EXTENDED CHANDRA DEEP FIELD-SOUTH

Energy Technology Data Exchange (ETDEWEB)

Hsieh, Bau-Ching; Wang, Wei-Hao; Hsieh, Chih-Chiang; Lin, Lihwai; Lim, Jeremy; Ho, Paul T. P. [Institute of Astrophysics and Astronomy, Academia Sinica, P.O. Box 23-141, Taipei 106, Taiwan (China); Yan Haojing [Department of Physics and Astronomy, University of Missouri, Columbia, MO 65211 (United States)

2012-12-15

We present ultra-deep J and K{sub S} imaging observations covering a 30' Multiplication-Sign 30' area of the Extended Chandra Deep Field-South (ECDFS) carried out by our Taiwan ECDFS Near-Infrared Survey (TENIS). The median 5{sigma} limiting magnitudes for all detected objects in the ECDFS reach 24.5 and 23.9 mag (AB) for J and K{sub S} , respectively. In the inner 400 arcmin{sup 2} region where the sensitivity is more uniform, objects as faint as 25.6 and 25.0 mag are detected at 5{sigma}. Thus, this is by far the deepest J and K{sub S} data sets available for the ECDFS. To combine TENIS with the Spitzer IRAC data for obtaining better spectral energy distributions of high-redshift objects, we developed a novel deconvolution technique (IRACLEAN) to accurately estimate the IRAC fluxes. IRACLEAN can minimize the effect of blending in the IRAC images caused by the large point-spread functions and reduce the confusion noise. We applied IRACLEAN to the images from the Spitzer IRAC/MUSYC Public Legacy in the ECDFS survey (SIMPLE) and generated a J+K{sub S} -selected multi-wavelength catalog including the photometry of both the TENIS near-infrared and the SIMPLE IRAC data. We publicly release the data products derived from this work, including the J and K{sub S} images and the J+K{sub S} -selected multi-wavelength catalog.

Chandra and the VLT Jointly Investigate the Cosmic X-Ray Background

Science.gov (United States)

2001-03-01

Summary Important scientific advances often happen when complementary investigational techniques are brought together . In the present case, X-ray and optical/infrared observations with some of the world's foremost telescopes have provided the crucial information needed to solve a 40-year old cosmological riddle. Very detailed observations of a small field in the southern sky have recently been carried out, with the space-based NASA Chandra X-Ray Observatory as well as with several ground-based ESO telescopes, including the Very Large Telescope (VLT) at the Paranal Observatory (Chile). Together, they have provided the "deepest" combined view at X-ray and visual/infrared wavelengths ever obtained into the distant Universe. The concerted observational effort has already yielded significant scientific results. This is primarily due to the possibility to 'identify' most of the X-ray emitting objects detected by the Chandra X-ray Observatory on ground-based optical/infrared images and then to determine their nature and distance by means of detailed (spectral) observations with the VLT . In particular, there is now little doubt that the so-called 'X-ray background' , a seemingly diffuse short-wave radiation first detected in 1962, in fact originates in a vast number of powerful black holes residing in active nuclei of distant galaxies . Moreover, the present investigation has permitted to identify and study in some detail a prime example of a hitherto little known type of object, a distant, so-called 'Type II Quasar' , in which the central black hole is deeply embedded in surrounding gas and dust. These achievements are just the beginning of a most fruitful collaboration between "space" and "ground". It is yet another impressive demonstration of the rapid progress of modern astrophysics, due to the recent emergence of a new generation of extremely powerful instruments. PR Photo 09a/01 : Images of a small part of the Chandra Deep Field South , obtained with ESO telescopes

FRONTIER FIELDS CLUSTERS: DEEP CHANDRA OBSERVATIONS OF THE COMPLEX MERGER MACS J1149.6+2223

Energy Technology Data Exchange (ETDEWEB)

Ogrean, G. A.; Weeren, R. J. van; Jones, C.; Forman, W.; Andrade-Santos, F.; Murray, S. S.; Nulsen, P.; Bulbul, E.; Kraft, R.; Randall, S. [Harvard-Smithsonian Center for Astrophysics, 60 Garden Street, Cambridge, MA 02138 (United States); Dawson, W. A. [Lawrence Livermore National Lab, 7000 East Avenue, Livermore, CA 94550 (United States); Golovich, N. [University of California, One Shields Avenue, Davis, CA 95616 (United States); Roediger, E. [Astronomy and Astrophysics Section, Dublin Institute for Advanced Studies, 31 Fitzwilliam Place, Dublin 2 (Ireland); Zitrin, A.; Sayers, J. [Cahill Center for Astronomy and Astrophysics, California Institute of Technology, MC 249-17, Pasadena, CA 91125 (United States); Goulding, A. [Department of Astrophysical Sciences, Princeton University, Princeton, NJ 08544 (United States); Umetsu, K. [Institute of Astronomy and Astrophysics, Academia Sinica, P.O. Box 23-141, Taipei 10617, Taiwan (China); Mroczkowski, T. [U.S. Naval Research Laboratory, 4555 Overlook Avenue SW, Washington, DC 20375 (United States); Bonafede, A. [Hamburger Sternwarte, Universität Hamburg, Gojenbergsweg 112, D-21029 Hamburg (Germany); Churazov, E., E-mail: gogrean@cfa.harvard.edu [Max Planck Institute for Astrophysics, Karl-Schwarzschild-Str. 1, D-85741, Garching (Germany); and others

2016-03-10

The Hubble Space Telescope Frontier Fields cluster MACS J1149.6+2223 is one of the most complex merging clusters, believed to consist of four dark matter halos. We present results from deep (365 ks) Chandra observations of the cluster, which reveal the most distant cold front (z  =  0.544) discovered to date. In the cluster outskirts, we also detect hints of a surface brightness edge that could be the bow shock preceding the cold front. The substructure analysis of the cluster identified several components with large relative radial velocities, thus indicating that at least some collisions occur almost along the line of sight. The inclination of the mergers with respect to the plane of the sky poses significant observational challenges at X-ray wavelengths. MACS J1149.6+2223 possibly hosts a steep-spectrum radio halo. If the steepness of the radio halo is confirmed, then the radio spectrum, combined with the relatively regular ICM morphology, could indicate that MACS J1149.6+2223 is an old merging cluster.

Chandra Reviews Black Hole Musical: Epic But Off-Key

Science.gov (United States)

2006-10-01

A gigantic sonic boom generated by a supermassive black hole has been found with NASA's Chandra X-ray Observatory, along with evidence for a cacophony of deep sound. This discovery was made by using data from the longest X-ray observation ever of M87, a nearby giant elliptical galaxy. M87 is centrally located in the Virgo cluster of galaxies and is known to harbor one of the Universe's most massive black holes. Scientists detected loops and rings in the hot, X-ray emitting gas that permeates the cluster and surrounds the galaxy. These loops provide evidence for periodic eruptions that occurred near the supermassive black hole, and that generate changes in pressure, or pressure waves, in the cluster gas that manifested themselves as sound. Chandra Low Energy X-ray Images of M87 Chandra Low Energy X-ray Images of M87 "We can tell that many deep and different sounds have been rumbling through this cluster for most of the lifetime of the Universe," said William Forman of the Harvard-Smithsonian Center for Astrophysics (CfA). The outbursts in M87, which happen every few million years, prevent the huge reservoir of gas in the cluster from cooling and forming many new stars. Without these outbursts and resultant heating, M87 would not be the elliptical galaxy it is today. "If this black hole wasn't making all of this noise, M87 could have been a completely different type of galaxy," said team member Paul Nulsen, also of the CfA, "possibly a huge spiral galaxy about 30 times brighter than the Milky Way." Chandra High Energy X-ray Image of M87 Chandra High Energy X-ray Image of M87 The outbursts result when material falls toward the black hole. While most of the matter is swallowed, some of it was violently ejected in jets. These jets are launched from regions close to the black hole (neither light nor sound can escape from the black hole itself) and push into the cluster's gas, generating cavities and sound which then propagate outwards. Chandra's M87 observations also

Clusters, groups, and filaments in the Chandra deep field-south up to redshift 1

International Nuclear Information System (INIS)

Dehghan, S.; Johnston-Hollitt, M.

2014-01-01

We present a comprehensive structure detection analysis of the 0.3 deg 2 area of the MUSYC-ACES field, which covers the Chandra Deep Field-South (CDFS). Using a density-based clustering algorithm on the MUSYC and ACES photometric and spectroscopic catalogs, we find 62 overdense regions up to redshifts of 1, including clusters, groups, and filaments. We also present the detection of a relatively small void of ∼10 Mpc 2 at z ∼ 0.53. All structures are confirmed using the DBSCAN method, including the detection of nine structures previously reported in the literature. We present a catalog of all structures present, including their central position, mean redshift, velocity dispersions, and classification based on their morphological and spectroscopic distributions. In particular, we find 13 galaxy clusters and 6 large groups/small clusters. Comparison of these massive structures with published XMM-Newton imaging (where available) shows that 80% of these structures are associated with diffuse, soft-band (0.4-1 keV) X-ray emission, including 90% of all objects classified as clusters. The presence of soft-band X-ray emission in these massive structures (M 200 ≥ 4.9 × 10 13 M ☉ ) provides a strong independent confirmation of our methodology and classification scheme. In the closest two clusters identified (z < 0.13) high-quality optical imaging from the Deep2c field of the Garching-Bonn Deep Survey reveals the cD galaxies and demonstrates that they sit at the center of the detected X-ray emission. Nearly 60% of the clusters, groups, and filaments are detected in the known enhanced density regions of the CDFS at z ≅ 0.13, 0.52, 0.68, and 0.73. Additionally, all of the clusters, bar the most distant, are found in these overdense redshift regions. Many of the clusters and groups exhibit signs of ongoing formation seen in their velocity distributions, position within the detected cosmic web, and in one case through the presence of tidally disrupted central galaxies

Clusters, groups, and filaments in the Chandra deep field-south up to redshift 1

Energy Technology Data Exchange (ETDEWEB)

Dehghan, S.; Johnston-Hollitt, M., E-mail: siamak.dehghan@vuw.ac.nz [School of Chemical and Physical Sciences, Victoria University of Wellington, P.O. Box 600, Wellington 6140 (New Zealand)

2014-03-01

We present a comprehensive structure detection analysis of the 0.3 deg{sup 2} area of the MUSYC-ACES field, which covers the Chandra Deep Field-South (CDFS). Using a density-based clustering algorithm on the MUSYC and ACES photometric and spectroscopic catalogs, we find 62 overdense regions up to redshifts of 1, including clusters, groups, and filaments. We also present the detection of a relatively small void of ∼10 Mpc{sup 2} at z ∼ 0.53. All structures are confirmed using the DBSCAN method, including the detection of nine structures previously reported in the literature. We present a catalog of all structures present, including their central position, mean redshift, velocity dispersions, and classification based on their morphological and spectroscopic distributions. In particular, we find 13 galaxy clusters and 6 large groups/small clusters. Comparison of these massive structures with published XMM-Newton imaging (where available) shows that 80% of these structures are associated with diffuse, soft-band (0.4-1 keV) X-ray emission, including 90% of all objects classified as clusters. The presence of soft-band X-ray emission in these massive structures (M {sub 200} ≥ 4.9 × 10{sup 13} M {sub ☉}) provides a strong independent confirmation of our methodology and classification scheme. In the closest two clusters identified (z < 0.13) high-quality optical imaging from the Deep2c field of the Garching-Bonn Deep Survey reveals the cD galaxies and demonstrates that they sit at the center of the detected X-ray emission. Nearly 60% of the clusters, groups, and filaments are detected in the known enhanced density regions of the CDFS at z ≅ 0.13, 0.52, 0.68, and 0.73. Additionally, all of the clusters, bar the most distant, are found in these overdense redshift regions. Many of the clusters and groups exhibit signs of ongoing formation seen in their velocity distributions, position within the detected cosmic web, and in one case through the presence of tidally

Chandra Sees Shape of Universe During Formative, Adolescent Years

Science.gov (United States)

2003-03-01

Scientists using NASA's Chandra X-ray Observatory have taken a snapshot of the adolescent universe from about five billion years ago when the familiar web-like structure of galaxy chains and voids first emerged. The observation reveals distant and massive galaxies dotting the sky, clustered together under the gravitational attraction of deep, unseen pockets of dark matter. This provides important clues of how the universe matured from its chaotic beginnings to its elegant structure we see today. These results are presented today in a press conference at the meeting of the High Energy Astrophysics Division of the American Astronomical Society at Mt. Tremblant, Quebec. "Piece by piece, we are assembling a photo album of the universe through the ages," said Yuxuan Yang, a doctorate candidate at the University of Maryland, College Park, who conducted the analysis. "Last month we saw a picture of the infant universe taken with the Wilkinson Microwave Anisotropy Probe. Now we can add a snapshot of its adolescence." The Chandra observation traced a patch of sky known as the Lockman Hole in the constellation Ursa Major (containing the Big Dipper). Chandra saw a rich density of active galaxies, seven times denser than what has been detected in previous optical and radio surveys at similar distances. This provides the clearest picture yet at the large-scale structure of the universe at such distances (and age), according to Dr. Richard Mushotzky of NASA Goddard Space Flight Center in Greenbelt, Md., who led the observation. Lockman Hole JPEG, TIFF, PS An image that has been "blurred" to allow better view of the structures outlined by the X-ray sources. The color represents the spectra of the AGN. The red color indicates the sources on average radiates at longer wavelength while green and blue colors indicates the sources radiates at shorter wavelength. The Green and blue regions appear to form a wall, or shows more lumpiness than the "red" sources. If one could capture the

The First Chandra Field

Energy Technology Data Exchange (ETDEWEB)

Weisskopf, Martin C.; /NASA, Marshall; Aldcroft, Thomas L.; /Harvard-Smithsonian Ctr. Astrophys.; Cameron, Robert A.; /Harvard-Smithsonian Ctr. Astrophys. /SLAC; Gandhi,; Foellmi, Cedric; /European Southern Obs., Chile; Elsner, Ronald F.; /NASA, Marshall; Patel, Sandeep K.; /USRA, Huntsville; Wu, Kinwah; /Mullard Space Sci. Lab.; O' Dell, Stephen; /NASA, Marshall

2005-09-09

Before the official first-light images, the Chandra X-ray Observatory obtained an X-ray image of the field to which its focal plane was first exposed. We describe this historic observation and report our study of the first Chandra field. Chandra's Advanced CCD Imaging Spectrometer (ACIS) detected 15 X-ray sources, the brightest being dubbed ''Leon X-1'' to honor the Chandra Telescope Scientist, Leon Van Speybroeck. Based upon our analysis of the X-ray data and spectroscopy at the European Southern Observatory (ESO; La Silla, Chile), we find that Leon X-1 is a Type-1 (unobscured) active galactic nucleus (AGN) at a redshift z = 0.3207. Leon X-1 exhibits strong Fe II emission and a broad-line Balmer decrement that is unusually flat for an AGN. Within the context of the Eigenvector-1 correlation space, these properties suggest that Leon X-1 may be a massive ({ge} 10{sup 9} M{sub {circle_dot}}) black hole, accreting at a rate approaching its Eddington limit.

Second Chandra Instrument Activated August 28

Science.gov (United States)

1999-08-01

Cambridge, MA--NASA's Chandra X-ray Observatory opened a new era in astronomy Saturday, August 28, by making the most precise measurements ever recorded of the energy output from the 10 million degree corona of a star. Last weekend's observations came after the successful activation of an instrument developed by MIT that will allow a one-thousand-fold improvement in the capability to measure X-ray spectra from space. The new measurements, made with the High Energy Transmission Grating Spectrometer, join spectacular images taken last week by Chandra of the aftermath of a gigantic stellar explosion. The spectrometer is one of four key instruments aboard Chandra, and the second to be activated. The others will be turned on over the next two weeks. The spectrometer activated yesterday spreads the X-rays from Chandra's mirrors into a spectrum, much as a prism spreads light into its colors. The spectrum then can be read by Chandra's imaging detectors like a kind of cosmic bar code from which scientists can deduce the chemical composition and temperature of the corona. A corona is a region of hot gas and magnetic loops that extend hundreds of thousands of miles above the star's visible surface and is best studied with X-rays. "The success of the new spectrometer is definitely a major milestone for modern astronomy," said MIT Professor Claude R. Canizares, principal investigator for the instrument and associate director of the Chandra X-ray Observatory Center (CXC). "Within the first hour we had obtained the best X-ray spectrum ever recorded for a celestial source. We can already see unexpected features that will teach us new things about stars and about matter at high temperatures." The spectrometer measured X-rays from the star Capella, which is 40 light years away in the constellation Auriga. Capella is actually two stars orbiting one another and possibly interacting in ways that pump extra heat into the corona, which appears more active than that of the Sun. How a star

Chandra Independently Determines Hubble Constant

Science.gov (United States)

2006-08-01

A critically important number that specifies the expansion rate of the Universe, the so-called Hubble constant, has been independently determined using NASA's Chandra X-ray Observatory. This new value matches recent measurements using other methods and extends their validity to greater distances, thus allowing astronomers to probe earlier epochs in the evolution of the Universe. "The reason this result is so significant is that we need the Hubble constant to tell us the size of the Universe, its age, and how much matter it contains," said Max Bonamente from the University of Alabama in Huntsville and NASA's Marshall Space Flight Center (MSFC) in Huntsville, Ala., lead author on the paper describing the results. "Astronomers absolutely need to trust this number because we use it for countless calculations." Illustration of Sunyaev-Zeldovich Effect Illustration of Sunyaev-Zeldovich Effect The Hubble constant is calculated by measuring the speed at which objects are moving away from us and dividing by their distance. Most of the previous attempts to determine the Hubble constant have involved using a multi-step, or distance ladder, approach in which the distance to nearby galaxies is used as the basis for determining greater distances. The most common approach has been to use a well-studied type of pulsating star known as a Cepheid variable, in conjunction with more distant supernovae to trace distances across the Universe. Scientists using this method and observations from the Hubble Space Telescope were able to measure the Hubble constant to within 10%. However, only independent checks would give them the confidence they desired, considering that much of our understanding of the Universe hangs in the balance. Chandra X-ray Image of MACS J1149.5+223 Chandra X-ray Image of MACS J1149.5+223 By combining X-ray data from Chandra with radio observations of galaxy clusters, the team determined the distances to 38 galaxy clusters ranging from 1.4 billion to 9.3 billion

The Cosmic History of Black Hole Accretion from Chandra X-ray Stacking

Science.gov (United States)

Treister, Ezequiel; Urry, C.; Schawinski, K.; Lee, N.; Natarajan, P.; Volonteri, M.; Sanders, D. B.

2012-05-01

In order to fully understand galaxy formation we need to know when in the cosmic history are black holes growing more intensively, in what type of galaxies this growth is happening and what fraction of these sources are invisible at most wavelengths due to obscuration. We take advantage of the rich multi-wavelength data available in the Chandra Deep Field South (CDF-S), including the 4 Msec Chandra observations (the deepest X-ray data to date), in order to measure the amount of black hole accretion as a function of cosmic history, from z 0 to z 6. We obtain stacked rest-frame X-ray spectra for samples of galaxies binned in terms of their IR luminosity, stellar mass and other galaxy properties. We find that the AGN fraction and their typical luminosities, and thus black hole accretion rates, increase with IR luminosity and stellar mass. The integrated intensity at high energies indicates that a significant fraction of the total black hole growth, 22%, occurs in heavily-obscured systems that are not individually detected in even the deepest X-ray observations. We find evidence for a strong connection between significant black hole growth events and major galaxy mergers from z 0 to z 3, while less spectacular but longer accretion episodes are most likely due to other (stochastic) processes. E.T. and K.S. gratefully acknowledges the support provided by NASA through Chandra Postdoctoral Fellowship Award Numbers PF8-90055 and PF9-00069, respectively issued by the Chandra X-ray Observatory Center. E.T. also thanks support by NASA through Chandra Award SP1-12005X Center of Excellence in Astrophysics and Associated Technologies (PFB 06). C. M. Urry acknowledges support from NSF Grants AST-0407295, AST-0449678, AST-0807570, and Yale University.

Black hole growth and starburst activity at z = 0.6-4 in the Chandra Deep Field South. Host galaxies properties of obscured AGN

Science.gov (United States)

Brusa, M.; Fiore, F.; Santini, P.; Grazian, A.; Comastri, A.; Zamorani, G.; Hasinger, G.; Merloni, A.; Civano, F.; Fontana, A.; Mainieri, V.

2009-12-01

Aims: The co-evolution of host galaxies and the active black holes which reside in their centre is one of the most important topics in modern observational cosmology. Here we present a study of the properties of obscured active galactic nuclei (AGN) detected in the CDFS 1 Ms observation and their host galaxies. Methods: We limited the analysis to the MUSIC area, for which deep K-band observations obtained with ISAAC@VLT are available, ensuring accurate identifications of the counterparts of the X-ray sources as well as reliable determination of photometric redshifts and galaxy parameters, such as stellar masses and star formation rates. In particular, we: 1) refined the X-ray/infrared/optical association of 179 sources in the MUSIC area detected in the Chandra observation; 2) studied the host galaxies observed and rest frame colors and properties. Results: We found that X-ray selected (LX ⪆ 1042 erg s-1) AGN show Spitzer colors consistent with both AGN and starburst dominated infrared continuum; the latter would not have been selected as AGN from infrared diagnostics. The host galaxies of X-ray selected obscured AGN are all massive (Mast > 1010 M_⊙) and, in 50% of the cases, are also actively forming stars (1/SSFR mass up to a value of 30% at z > 1 and Mast > 3 × 1011 M_⊙, a fraction significantly higher than in the local Universe for AGN of similar luminosities. Tables [see full textsee full textsee full text] and [see full textsee full textsee full text] are only available in electronic form at http://www.aanda.org

Multielement determination of major-to-ultratrace elements in deep-seawater salts by ICP-AES and ICP-MS

International Nuclear Information System (INIS)

Sakai, Takeshi; Nakagawa, Koji; Nakajima, Hiroshi; Itoh, Akihide; Ji, Shan; Haraguchi, Hiroki

2002-01-01

Major-to-ultratrace elements in deep-seawater salts were determined by ICP-AES and ICP-MS, after they were separated into the water-soluble, acid-soluble, and insoluble particle components. Deep-seawater salts were prepared from seawater collected at 344 m deep near the off-shore of Cape Muroto in Kochi Prefecture. The major and minor elements in salts were determined by ICP-AES after appropriate dilution with pure water. Trace and ultratrace elements in the water-soluble and acid-soluble components were preconcentrated by a chelating resin preconcentration method. In addition, the major to-ultratrace elements in the insoluble particle component were determined by ICP-AES and ICP-MS, after acid-digestion using HNO 3 /HF/HClO 4 . As a result, 21-35 elements in deep-seawater salts could be determined over the wide concentration range. It was found that the elements, such as Al, V, Fe, Mn, Co, Cu, Zn, and rare earth elements, were more abundant in the acid-soluble component of deep-seawater salts, which may play some essential roles in physiological effectiveness for intake of salt. (author)

Implications from XMM and Chandra Source Catalogs for Future Studies with Lynx

Science.gov (United States)

Ptak, Andrew

2018-01-01

Lynx will perform extremely sensitive X-ray surveys by combining very high-resolution imaging over a large field of view with a high effective area. These will include deep planned surveys and serendipitous source surveys. Here we discuss implications that can be gleaned from current Chandra and XMM-Newton serendipitous source surveys. These current surveys have discovered novel sources such as tidal disruption events, binary AGN, and ULX pulsars. In addition these surveys have detected large samples of normal galaxies, low-luminosity AGN and quasars due to the wide-area coverage of the Chandra and XMM-Newton source catalogs, allowing the evolution of these phenonema to be explored. The wide area Lynx surveys will probe down further in flux and will be coupled with very sensitive wide-area surveys such as LSST and SKA, allowing for detailed modeling of their SEDs and the discovery of rare, exotic sources and transient events.

IDENTIFYING THE LOCATION IN THE HOST GALAXY OF THE SHORT GRB 111117A WITH THE CHANDRA SUBARCSECOND POSITION

Energy Technology Data Exchange (ETDEWEB)

Sakamoto, T.; Troja, E. [Center for Research and Exploration in Space Science and Technology (CRESST), NASA Goddard Space Flight Center, Greenbelt, MD 20771 (United States); Aoki, K. [Subaru Telescope, National Astronomical Observatory of Japan, 650 North A' ohoku Place, Hilo, HI 96720 (United States); Guiriec, S.; Barthelmy, S. D. [NASA Goddard Space Flight Center, Greenbelt, MD 20771 (United States); Im, M.; Jeon, Y. [Center for the Exploration of the Origin of the Universe (CEOU), Department of Physics and Astronomy, Seoul National University, Seoul, 151-747 (Korea, Republic of); Leloudas, G.; Malesani, D.; De Ugarte Postigo, A.; Andersen, M. I. [Dark Cosmology Centre, Niels Bohr Institute, University of Copenhagen, Juliane Maries Vej 30, DK-2100 Copenhagen O (Denmark); Melandri, A.; D' Avanzo, P. [INAF-Osservatorio Astronomico di Brera, via Bianchi 46, I-23807 Merate (Italy); Urata, Y. [Institute of Astronomy, National Central University, Chung-Li 32054, Taiwan (China); Xu, D. [Department of Particle Physics and Astronomy, The Weizmann Institute of Science, Rehovot 76100 (Israel); Gorosabel, J.; Sanchez-Ramirez, R. [Instituto de Astrofisica de Andalucia (CSIC), Glorieta de la Astronomia s/n, E-18008 Granada (Spain); Bai, J. [Yunnan Astronomical Observatory, Chinese Academy of Sciences, Kunming, Yunnan Province, 650011 (China); Briggs, M. S. [Center for Space Plasma and Aeronomic Research, University of Alabama in Huntsville, 320 Sparkman Drive, Huntsville, AL 35805 (United States); Foley, S. [Max-Planck-Institut fuer extraterrestrische Physik, Giessenbachstrasse 1, D-85748 Garching (Germany); and others

2013-03-20

We present our successful Chandra program designed to identify, with subarcsecond accuracy, the X-ray afterglow of the short GRB 111117A, which was discovered by Swift and Fermi. Thanks to our rapid target of opportunity request, Chandra clearly detected the X-ray afterglow, though no optical afterglow was found in deep optical observations. The host galaxy was clearly detected in the optical and near-infrared band, with the best photometric redshift of z=1.31{sub -0.23}{sup +0.46} (90% confidence), making it one of the highest known short gamma-ray burst (GRB) redshifts. Furthermore, we see an offset of 1.0 {+-} 0.2 arcsec, which corresponds to 8.4 {+-} 1.7 kpc, between the host and the afterglow position. We discuss the importance of using Chandra for obtaining subarcsecond X-ray localizations of short GRB afterglows to study GRB environments.

THE CHANDRA VARIABLE GUIDE STAR CATALOG

International Nuclear Information System (INIS)

Nichols, Joy S.; Lauer, Jennifer L.; Morgan, Douglas L.; Sundheim, Beth A.; Henden, Arne A.; Huenemoerder, David P.; Martin, Eric

2010-01-01

Variable stars have been identified among the optical-wavelength light curves of guide stars used for pointing control of the Chandra X-ray Observatory. We present a catalog of these variable stars along with their light curves and ancillary data. Variability was detected to a lower limit of 0.02 mag amplitude in the 4000-10000 A range using the photometrically stable Aspect Camera on board the Chandra spacecraft. The Chandra Variable Guide Star Catalog (VGUIDE) contains 827 stars, of which 586 are classified as definitely variable and 241 are identified as possibly variable. Of the 586 definite variable stars, we believe 319 are new variable star identifications. Types of variables in the catalog include eclipsing binaries, pulsating stars, and rotating stars. The variability was detected during the course of normal verification of each Chandra pointing and results from analysis of over 75,000 guide star light curves from the Chandra mission. The VGUIDE catalog represents data from only about 9 years of the Chandra mission. Future releases of VGUIDE will include newly identified variable guide stars as the mission proceeds. An important advantage of the use of space data to identify and analyze variable stars is the relatively long observations that are available. The Chandra orbit allows for observations up to 2 days in length. Also, guide stars were often used multiple times for Chandra observations, so many of the stars in the VGUIDE catalog have multiple light curves available from various times in the mission. The catalog is presented as both online data associated with this paper and as a public Web interface. Light curves with data at the instrumental time resolution of about 2 s, overplotted with the data binned at 1 ks, can be viewed on the public Web interface and downloaded for further analysis. VGUIDE is a unique project using data collected during the mission that would otherwise be ignored. The stars available for use as Chandra guide stars are

A HIGH FIDELITY SAMPLE OF COLD FRONT CLUSTERS FROM THE CHANDRA ARCHIVE

International Nuclear Information System (INIS)

Owers, Matt S.; Nulsen, Paul E. J.; Markevitch, Maxim; Couch, Warrick J.

2009-01-01

This paper presents a sample of 'cold front' clusters selected from the Chandra archive. The clusters are selected based purely on the existence of surface brightness edges in their Chandra images which are modeled as density jumps. A combination of the derived density and temperature jumps across the fronts is used to select nine robust examples of cold front clusters: 1ES0657 - 558, Abell 1201, Abell 1758N, MS1455.0+2232, Abell 2069, Abell 2142, Abell 2163, RXJ1720.1+2638, and Abell 3667. This sample is the subject of an ongoing study aimed at relating cold fronts to cluster merger activity, and understanding how the merging environment affects the cluster constituents. Here, temperature maps are presented along with the Chandra X-ray images. A dichotomy is found in the sample in that there exists a subsample of cold front clusters which are clearly mergers based on their X-ray morphologies, and a second subsample of clusters which harbor cold fronts, but have surprisingly relaxed X-ray morphologies, and minimal evidence for merger activity at other wavelengths. For this second subsample, the existence of a cold front provides the sole evidence for merger activity at X-ray wavelengths. We discuss how cold fronts can provide additional information which may be used to constrain merger histories, and also the possibility of using cold fronts to distinguish major and minor mergers.

The Chandra X-ray Observatory PSF Library

Science.gov (United States)

Karovska, M.; Beikman, S. J.; Elvis, M. S.; Flanagan, J. M.; Gaetz, T.; Glotfelty, K. J.; Jerius, D.; McDowell, J. C.; Rots, A. H.

Pre-flight and on-orbit calibration of the Chandra X-Ray Observatory provided a unique base for developing detailed models of the optics and detectors. Using these models we have produced a set of simulations of the Chandra point spread function (PSF) which is available to the users via PSF library files. We describe here how the PSF models are generated and the design and content of the Chandra PSF library files.

A Deep Chandra ACIS Study of NGC 4151. III. The Line Emission and Spectral Analysis of the Ionization Cone

Science.gov (United States)

Wang, Junfeng; Fabbiano, Giuseppina; Elvis, Martin; Risaliti, Guido; Karovska, Margarita; Zezas, Andreas; Mundell, Carole G.; Dumas, Gaelle; Schinnerer, Eva

2011-11-01

This paper is the third in a series in which we present deep Chandra ACIS-S imaging spectroscopy of the Seyfert 1 galaxy NGC 4151, devoted to study its complex circumnuclear X-ray emission. Emission features in the soft X-ray spectrum of the bright extended emission (L 0.3-2 keV ~ 1040 erg s-1) at r > 130 pc (2'') are consistent with blended brighter O VII, O VIII, and Ne IX lines seen in the Chandra HETGS and XMM-Newton RGS spectra below 2 keV. We construct emission line images of these features and find good morphological correlations with the narrow-line region clouds mapped in [O III] λ5007. Self-consistent photoionization models provide good descriptions of the spectra of the large-scale emission, as well as resolved structures, supporting the dominant role of nuclear photoionization, although displacement of optical and X-ray features implies a more complex medium. Collisionally ionized emission is estimated to be lsim12% of the extended emission. Presence of both low- and high-ionization spectral components and extended emission in the X-ray image perpendicular to the bicone indicates leakage of nuclear ionization, likely filtered through warm absorbers, instead of being blocked by a continuous obscuring torus. The ratios of [O III]/soft X-ray flux are approximately constant (~15) for the 1.5 kpc radius spanned by these measurements, indicating similar relative contributions from the low- and high-ionization gas phases at different radial distances from the nucleus. If the [O III] and X-ray emission arise from a single photoionized medium, this further implies an outflow with a wind-like density profile. Using spatially resolved X-ray features, we estimate that the mass outflow rate in NGC 4151 is ~2 M ⊙ yr-1 at 130 pc and the kinematic power of the ionized outflow is 1.7 × 1041 erg s-1, approximately 0.3% of the bolometric luminosity of the active nucleus in NGC 4151.

Stellar Forensics with Striking Image from Chandra

Science.gov (United States)

2007-10-01

A spectacular new image shows how complex a star's afterlife can be. By studying the details of this image made from a long observation by NASA's Chandra X-ray Observatory, astronomers can better understand how some stars die and disperse elements like oxygen into the next generation of stars and planets. At a distance of about 20,000 light years, G292.0+1.8 is one of only three supernova remnants in the Milky Way known to contain large amounts of oxygen. The image shows a rapidly expanding, intricately structured, debris field that contains, along with oxygen, other elements such as neon and silicon that were forged in the star before it exploded. Hard X-ray Image of G292.0+1.8 Hard X-ray Image of G292.0+1.8 "We are finding that, just like snowflakes, each supernova remnant is complicated and beautiful in its own way," said Sangwook Park of Penn State who led the work, released in conjunction with the "8 Years of Chandra" symposium in Huntsville, Ala. The new, deep Chandra image - equaling nearly 6 days worth of observing time - shows an incredibly complex structure. Understanding the details of G292.0+1.8 is especially important because astronomers have considered it to be a "textbook" case of a supernova created by the death of a massive star. Chandra X-ray Image of G292.0+1.8 Chandra X-ray Image of G292.0+1.8 By mapping the distribution of X-rays in different energy bands, the Chandra image traces the distribution of chemical elements ejected in the supernova. The results imply that the explosion was not symmetrical. For example, blue (silicon and sulfur) and green (magnesium) are seen strongly in the upper right, while yellow and orange (oxygen) dominate the lower left. These elements light up at different temperatures, indicating that the temperature is higher in the upper right portion of G292.0+1.8. Slightly below and to the left of the center of G292.0+1.8 is a pulsar, a dense, rapidly rotating neutron star that remained behind after the original star

Macdonald difference operators and Harish-Chandra series

NARCIS (Netherlands)

Letzter, G.; Stokman, J.V.

2008-01-01

We analyse the centralizer of the Macdonald difference operator in an appropriate algebra of Weyl group invariant difference operators. We show that it coincides with Cherednik's commuting algebra of difference operators via an analog of the Harish-Chandra isomorphism. Analogs of Harish-Chandra

A CHANDRA OBSERVATION OF THE ECLIPSING WOLF-RAYET BINARY CQ Cep

Energy Technology Data Exchange (ETDEWEB)

Skinner, Stephen L. [CASA, Univ. of Colorado, Boulder, CO 80309-0389 (United States); Zhekov, Svetozar A. [Space Research and Technology Institute, Akad. G. Bonchev Str., Sofia, 1113 (Bulgaria); Güdel, Manuel [Dept. of Astrophysics, Univ. of Vienna, Türkenschanzstr. 17, A-1180 Vienna (Austria); Schmutz, Werner, E-mail: stephen.skinner@colorado.edu, E-mail: szhekov@space.bas.bg, E-mail: manuel.guedel@univie.ac.at, E-mail: werner.schmutz@pmodwrc.ch [Physikalisch-Meteorologisches Observatorium Davos and World Radiation Center (PMOD/WRC), Dorfstrasse 33, CH-7260 Davos Dorf (Switzerland)

2015-02-01

The short-period (1.64 d) near-contact eclipsing WN6+O9 binary system CQ Cep provides an ideal laboratory for testing the predictions of X-ray colliding wind shock theory at close separation where the winds may not have reached terminal speeds before colliding. We present results of a Chandra X-ray observation of CQ Cep spanning ∼1 day during which a simultaneous Chandra optical light curve was acquired. Our primary objective was to compare the observed X-ray properties with colliding wind shock theory, which predicts that the hottest shock plasma (T ≳ 20 MK) will form on or near the line-of-centers between the stars. The X-ray spectrum is strikingly similar to apparently single WN6 stars such as WR 134 and spectral lines reveal plasma over a broad range of temperatures T ∼ 4-40 MK. A deep optical eclipse was seen as the O star passed in front of the Wolf-Rayet star and we determine an orbital period P {sub orb} = 1.6412400 d. Somewhat surprisingly, no significant X-ray variability was detected. This implies that the hottest X-ray plasma is not confined to the region between the stars, at odds with the colliding wind picture and suggesting that other X-ray production mechanisms may be at work. Hydrodynamic simulations that account for such effects as radiative cooling and orbital motion will be needed to determine if the new Chandra results can be reconciled with the colliding wind picture.

Chandra Images Provide New Vision of Cosmic Explosions

Science.gov (United States)

1999-09-01

Images from NASA's Chandra X-ray Observatory released today reveal previously unobserved features in the remnants of three different supernova explosions. Two of the remnants G21.5-0.9 and PSR 0540-69 show dramatic details of the prodigious production of energetic particles by a rapidly rotating, highly magnetized neutron star, as well as the enormous shell structures produced by the explosions. The image of the third remnant, E0102-72, reveals puzzling spoke-like structures in its interior. G21.5-0.9, in the constellation of Scutum, is about 16,000 light years (1 light year = 6 trillion miles) from Earth. Chandra's image shows a bright nebula surrounded by a much larger diffuse cloud. Inside the inner nebula is a bright central source that is thought to be a rapidly rotating highly magnetized neutron star. A rotating neutron star acts like a powerful generator, creating intense electric voltages that accelerate electrons to speeds close to the speed of light. The total output of this generator is greater than a thousand suns. The fluffy appearance of the central nebula is thought to be due to magnetic field lines which constrain the motions of the high-energy electrons. "It's a remarkable image," said Dr. Patrick Slane of the Harvard-Smithsonian Center for Astrophysics. "Neither the inner core nor the outer shell has ever been seen before." "It is as though we have a set of Russian dolls, with structures embedded within structures," said Professor Gordon Garmire of Penn State University, and principal investigator of the Advanced CCD Imaging Spectrometer, the X-ray camera that was used to make two of the images. NASA's project scientist, Dr. Martin Weisskopf of the Marshall Space Flight Center said, "Chandra's capability to provide surprises and insights continues." PSR 0540-69 PSR 0540-69 The existence of a rotating neutron star, or pulsar, in the center of G21.5-0.9 is inferred from the appearance of the nebula and the energy distribution of X-rays and radio

Lunar Prospecting With Chandra

Science.gov (United States)

2003-09-01

Observations of the bright side of the Moon with NASA's Chandra X-ray Observatory have detected oxygen, magnesium, aluminum and silicon over a large area of the lunar surface. The abundance and distribution of those elements will help to determine how the Moon was formed. "We see X-rays from these elements directly, independent of assumptions about the mineralogy and other complications," said Jeremy Drake of the Harvard-Smithsonian Center for Astrophysics in Cambridge, Mass., at a press conference at the "Four Years with Chandra" symposium in Huntsville, Alabama. "We have Moon samples from the six widely-space Apollo landing sites, but remote sensing with Chandra can cover a much wider area," continued Drake. "It's the next best thing to being there, and it's very fast and cost-effective." The lunar X-rays are caused by fluorescence, a process similar to the way that light is produced in fluorescent lamps. Solar X-rays bombard the surface of the Moon, knock electrons out of the inner parts of the atoms, putting them in a highly unstable state. Almost immediately, other electrons rush to fill the gaps, and in the process convert their energy into the fluorescent X-rays seen by Chandra. According to the currently popular "giant impact" theory for the formation of the Moon, a body about the size of Mars collided with the Earth about 4.5 billion years ago. This impact flung molten debris from the mantle of both the Earth and the impactor into orbit around the Earth. Over the course of tens of millions of years, the debris stuck together to form the Moon. By measuring the amounts of aluminum and other elements over a wide area of the Moon and comparing them to the Earth's mantle, Drake and his colleagues plan to help test the giant impact hypothesis. "One early result," quipped Drake, "is that there is no evidence for large amounts of calcium, so cheese is not a major constituent of the Moon." Illustration of Earth's Geocorona Illustration of Earth's Geocorona The same

Identifying the Location in the Host Galaxy of Short GRB 1111l7A with the Chandra Sub- Arcsecond Position

Science.gov (United States)

Sakamoto, Takanori; Troja, E.; Aoki, K.; Guiriec, S.; Im, M.; Leloudas, G.; Malesani, D.; Melandri, A.; deUgartePostigo, A.; Urata, Y.;

Venkataraman, Prof. Chandra

Indian Academy of Sciences (India)

Elected: 2018 Section: Earth & Planetary Sciences. Venkataraman, Prof. Chandra Ph.D. (Univ. Calif., Los Angeles), FNAE, FNASc. Date of birth: 3 June 1963. Specialization: Aerosol Science & Engineering, Environmental & Climate Science, Atmospheric Science Address: Department of Chemical Engineering, Indian ...

NASA's Chandra Finds Black Holes Are "Green"

Science.gov (United States)

2006-04-01

Black holes are the most fuel efficient engines in the Universe, according to a new study using NASA's Chandra X-ray Observatory. By making the first direct estimate of how efficient or "green" black holes are, this work gives insight into how black holes generate energy and affect their environment. The new Chandra finding shows that most of the energy released by matter falling toward a supermassive black hole is in the form of high-energy jets traveling at near the speed of light away from the black hole. This is an important step in understanding how such jets can be launched from magnetized disks of gas near the event horizon of a black hole. Illustration of Fuel for a Black Hole Engine Illustration of Fuel for a Black Hole Engine "Just as with cars, it's critical to know the fuel efficiency of black holes," said lead author Steve Allen of the Kavli Institute for Particle Astrophysics and Cosmology at Stanford University, and the Stanford Linear Accelerator Center. "Without this information, we cannot figure out what is going on under the hood, so to speak, or what the engine can do." Allen and his team used Chandra to study nine supermassive black holes at the centers of elliptical galaxies. These black holes are relatively old and generate much less radiation than quasars, rapidly growing supermassive black holes seen in the early Universe. The surprise came when the Chandra results showed that these "quiet" black holes are all producing much more energy in jets of high-energy particles than in visible light or X-rays. These jets create huge bubbles, or cavities, in the hot gas in the galaxies. Animation of Black Hole in Elliptical Galaxy Animation of Black Hole in Elliptical Galaxy The efficiency of the black hole energy-production was calculated in two steps: first Chandra images of the inner regions of the galaxies were used to estimate how much fuel is available for the black hole; then Chandra images were used to estimate the power required to produce

Jet Power and Black Hole Assortment Revealed in New Chandra Image

Science.gov (United States)

2008-01-01

A dramatic new Chandra image of the nearby galaxy Centaurus A provides one of the best views to date of the effects of an active supermassive black hole. Opposing jets of high-energy particles can be seen extending to the outer reaches of the galaxy, and numerous smaller black holes in binary star systems are also visible. The image was made from an ultra-deep look at the galaxy Centaurus A, equivalent to more than seven days of continuous observations. Centaurus A is the nearest galaxy to Earth that contains a supermassive black hole actively powering a jet. X-ray Image of Centaurus A, Labeled X-ray Image of Centaurus A, Labeled A prominent X-ray jet extending for 13,000 light years points to the upper left in the image, with a shorter "counterjet" aimed in the opposite direction. Astronomers think that such jets are important vehicles for transporting energy from the black hole to the much larger dimensions of a galaxy, and affecting the rate at which stars form there. High-energy electrons spiraling around magnetic field lines produce the X-ray emission from the jet and counterjet. This emission quickly saps the energy from the electrons, so they must be continually reaccelerated or the X-rays will fade out. Knot-like features in the jets detected in the Chandra image show where the acceleration of particles to high energies is currently occurring, and provides important clues to understanding the process that accelerates the electrons to near-light speeds. People Who Read This Also Read... NASA’s Swift Satellite Catches First Supernova in The Act of Exploding Black Holes Have Simple Feeding Habits Chandra Data Reveal Rapidly Whirling Black Holes Erratic Black Hole Regulates Itself The inner part of the X-ray jet close to the black hole is dominated by these knots of X-ray emission, which probably come from shock waves -- akin to sonic booms -- caused by the jet. Farther from the black hole there is more diffuse X-ray emission in the jet. The cause of particle

Chandra Discovers Cosmic Cannonball

Science.gov (United States)

2007-11-01

One of the fastest moving stars ever seen has been discovered with NASA's Chandra X-ray Observatory. This cosmic cannonball is challenging theories to explain its blistering speed. Astronomers used Chandra to observe a neutron star, known as RX J0822-4300, over a period of about five years. During that span, three Chandra observations clearly show the neutron star moving away from the center of the Puppis A supernova remnant. This remnant is the stellar debris field created during the same explosion in which the neutron star was created about 3700 years ago. Chandra X-ray Image of RX J0822-4300 in Puppis A Chandra X-ray Image of RX J0822-4300 in Puppis A By combining how far it has moved across the sky with its distance from Earth, astronomers determined the neutron star is moving at over 3 million miles per hour. At this rate, RX J0822-4300 is destined to escape from the Milky Way after millions of years, even though it has only traveled about 20 light years so far. "This star is moving at 3 million miles an hour, but it's so far away that the apparent motion we see in five years is less than the height of the numerals in the date on a penny, seen from the length of a football field," said Frank Winkler of Middlebury College in Vermont. "It's remarkable, and a real testament to the power of Chandra, that such a tiny motion can be measured." Labeled Image of RX J0822-4300 in Puppis A Labeled Image of RX J0822-4300 in Puppis A "Just after it was born, this neutron star got a one-way ticket out of the Galaxy," said co-author Robert Petre of NASA's Goddard Space Flight Center in Greenbelt, Md. "Astronomers have seen other stars being flung out of the Milky Way, but few as fast as this." So-called hypervelocity stars have been previously discovered shooting out of the Milky Way with speeds around one million miles per hour. One key difference between RX J0822-4300 and these other reported galactic escapees is the source of their speed. The hypervelocity stars are

Nirab Chandra Adhikary

Indian Academy of Sciences (India)

Home; Journals; Bulletin of Materials Science. Nirab Chandra Adhikary. Articles written in Bulletin of Materials Science. Volume 37 Issue 7 December 2014 pp 1613-1624. Enhancement of proton conductivity of sulfonated polystyrene membrane prepared by plasma polymerization process · Bhabesh Kumar Nath Aziz Khan ...

Deep Chandra Observation and Numerical Studies of the Nearest Cluster Cold Front in the Sky

Science.gov (United States)

Werner, N.; ZuHone, J. A.; Zhuravleva, I.; Ichinohe, Y.; Simionescu, A.; Allen, S. W.; Markevitch, M.; Fabian, A. C.; Keshet, U.; Roediger, E.;

subhas chandra saha

Indian Academy of Sciences (India)

Home; Journals; Sadhana. SUBHAS CHANDRA SAHA. Articles written in Sadhana. Volume 41 Issue 5 May 2016 pp 549-559. A comparative study of multiple regression analysis and back propagation neural network approaches on plain carbon steel in submerged-arc welding · ABHIJIT SARKAR PRASENJIT DEY R N ...

NASA Unveils First Images From Chandra X-Ray Observatory

Science.gov (United States)

1999-08-01

Extraordinary first images from NASA's Chandra X-ray Observatory trace the aftermath of a gigantic stellar explosion in such stunning detail that scientists can see evidence of what may be a neutron star or black hole near the center. Another image shows a powerful X-ray jet blasting 200,000 light years into intergalactic space from a distant quasar. Released today, both images confirm that NASA's newest Great Observatory is in excellent health and its instruments and optics are performing up to expectations. Chandra, the world's largest and most sensitive X-ray telescope, is still in its orbital check-out and calibration phase. "When I saw the first image, I knew that the dream had been realized," said Dr. Martin Weisskopf, Chandra Project Scientist, NASA's Marshall Space Flight Center, Huntsville, AL. "This observatory is ready to take its place in the history of spectacular scientific achievements." "We were astounded by these images," said Harvey Tananbaum, Director of the Smithsonian Astrophysical Observatory's Chandra X- ray Center, Cambridge, MA. "We see the collision of the debris from the exploded star with the matter around it, we see shock waves rushing into interstellar space at millions of miles per hour, and, as a real bonus, we see for the first time a tantalizing bright point near the center of the remnant that could possibly be a collapsed star associated with the outburst." Chandra's PKS 0637-752 PKS 0637-752 After the telescope's sunshade door was opened last week, one of the first images taken was of the 320-year-old supernova remnant Cassiopeia A, which astronomers believe was produced by the explosion of a massive star. Material blasted into space from the explosion crashed into surrounding material at 10 million miles per hour. This collision caused violent shock waves, like massive sonic booms, creating a vast 50-million degree bubble of X-ray emitting gas. Heavy elements in the hot gas produce X-rays of specific energies. Chandra's ability

Simultaneous Chandra/Swift Observations of the RT Cru Symbiotic System

Science.gov (United States)

Kashyap, Vinay; Kennea, J. A.; Karovska, M.; Calibration, Chandra

2013-04-01

The symbiotic star RT Cru was observed simultaneously by the Chandra/HRC-I and Swift/XRT in Dec 2012. The observations were carried out as part of a program to calibrate the Chandra PSF. The Chandra light curve shows a number of brightenings by factors of 2, with strong indications of a softening of the spectrum at these times. Swift observations cover a brief part of the Chandra light curve, and the intensities over this duration are tightly correlated. The Swift spectral data confirm the anticorrelation between intensity and spectral hardness. However, there are differences in the correlations at different periods that are not understood. We report on our analysis of the data, with emphasis on the spectral modeling at different times and intensity levels, and discuss the implications of the results on the emission mechanisms on symbiotic stars. We also report our inferences on the structure and energy dependence of the Chandra PSF anomaly, and on the high-energy cross-calibration between the HRC-I and XRT. This work is supported by the NASA contract NAS8-03060 to the Chandra X-ray Center.

Chandra "Hears" A Black Hole For The First Time

Science.gov (United States)

2003-09-01

NASA's Chandra X-ray Observatory detected sound waves, for the first time, from a super-massive black hole. The "note" is the deepest ever detected from an object in the universe. The tremendous amounts of energy carried by these sound waves may solve a longstanding problem in astrophysics. The black hole resides in the Perseus cluster, located 250 million light years from Earth. In 2002, astronomers obtained a deep Chandra observation that shows ripples in the gas filling the cluster. These ripples are evidence for sound waves that have traveled hundreds of thousands of light years away from the cluster's central black hole. perseus animation Illustration of Ripples in Perseus "We have observed the prodigious amounts of light and heat created by black holes, now we have detected the sound," said Andrew Fabian of the Institute of Astronomy (IoA) in Cambridge, England, and leader of the study. In musical terms, the pitch of the sound generated by the black hole translates into the note of B flat. But, a human would have no chance of hearing this cosmic performance, because the note is 57 octaves lower than middle-C (by comparison a typical piano contains only about seven octaves). At a frequency over a million, billion times deeper than the limits of human hearing, this is the deepest note ever detected from an object in the universe. "The Perseus sound waves are much more than just an interesting form of black hole acoustics," said Steve Allen, also of the IoA and a co-investigator in the research. "These sound waves may be the key in figuring out how galaxy clusters, the largest structures in the universe, grow," Allen said. For years astronomers have tried to understand why there is so much hot gas in galaxy clusters and so little cool gas. Hot gas glowing with X-rays should cool, and the dense central gas should cool the fastest. The pressure in this cool central gas should then fall, causing gas further out to sink in towards the galaxy, forming trillions of

The Chandra Source Catalog: Storage and Interfaces

Science.gov (United States)

van Stone, David; Harbo, Peter N.; Tibbetts, Michael S.; Zografou, Panagoula; Evans, Ian N.; Primini, Francis A.; Glotfelty, Kenny J.; Anderson, Craig S.; Bonaventura, Nina R.; Chen, Judy C.; Davis, John E.; Doe, Stephen M.; Evans, Janet D.; Fabbiano, Giuseppina; Galle, Elizabeth C.; Gibbs, Danny G., II; Grier, John D.; Hain, Roger; Hall, Diane M.; He, Xiang Qun (Helen); Houck, John C.; Karovska, Margarita; Kashyap, Vinay L.; Lauer, Jennifer; McCollough, Michael L.; McDowell, Jonathan C.; Miller, Joseph B.; Mitschang, Arik W.; Morgan, Douglas L.; Mossman, Amy E.; Nichols, Joy S.; Nowak, Michael A.; Plummer, David A.; Refsdal, Brian L.; Rots, Arnold H.; Siemiginowska, Aneta L.; Sundheim, Beth A.; Winkelman, Sherry L.

2009-09-01

The Chandra Source Catalog (CSC) is part of the Chandra Data Archive (CDA) at the Chandra X-ray Center. The catalog contains source properties and associated data objects such as images, spectra, and lightcurves. The source properties are stored in relational databases and the data objects are stored in files with their metadata stored in databases. The CDA supports different versions of the catalog: multiple fixed release versions and a live database version. There are several interfaces to the catalog: CSCview, a graphical interface for building and submitting queries and for retrieving data objects; a command-line interface for property and source searches using ADQL; and VO-compliant services discoverable though the VO registry. This poster describes the structure of the catalog and provides an overview of the interfaces.

Chandra Source Catalog: Background Determination and Source Detection

Science.gov (United States)

McCollough, Michael L.; Rots, A. H.; Primini, F. A.; Evans, I. N.; Glotfelty, K. J.; Hain, R.; Anderson, C. S.; Bonaventura, N. R.; Chen, J. C.; Davis, J. E.; Doe, S. M.; Evans, J. D.; Fabbiano, G.; Galle, E.; Gibbs, D. G.; Grier, J. D.; Hall, D. M.; Harbo, P. N.; He, X.; Houck, J. C.; Karovska, M.; Lauer, J.; McDowell, J. C.; Miller, J. B.; Mitschang, A. W.; Morgan, D. L.; Nichols, J. S.; Nowak, M. A.; Plummer, D. A.; Refsdal, B. L.; Siemiginowska, A. L.; Sundheim, B. A.; Tibbetts, M. S.; Van Stone, D. W.; Winkelman, S. L.; Zografou, P.

2009-01-01

The Chandra Source Catalog (CSC) is a major project in which all of the pointed imaging observations taken by the Chandra X-Ray Observatory will used to generate the most extensive X-ray source catalog produced to date. Early in the development of the CSC it was recognized that the ability to estimate local background levels in an automated fashion would be critical for essential CSC tasks such as source detection, photometry, sensitivity estimates, and source characterization. We present a discussion of how such background maps are created directly from the Chandra data and how they are used in source detection. The general background for Chandra observations is rather smoothly varying, containing only low spatial frequency components. However, in the case of ACIS data, a high spatial frequency component is added that is due to the readout streaks of the CCD chips. We discuss how these components can be estimated reliably using the Chandra data and what limitations and caveats should be considered in their use. We will discuss the source detection algorithm used for the CSC and the effects of the background images on the detection results. We will also touch on some the Catalog Inclusion and Quality Assurance criteria applied to the source detection results. This work is supported by NASA contract NAS8-03060 (CXC).

Distant Galaxies, Black Holes and Other Celestial Phenomena: NASA's Chandra X-ray Observatory Marks Four Years of Discovery Firsts

Science.gov (United States)

2003-09-01

Launched in 1999, NASA's Chandra X-ray Observatory promised to be one of the world's most powerful tools to better understand the structure and evolution of the universe - and it has lived up to expectations. "In four short years, Chandra has achieved numerous scientific firsts, revealing new details on all categories of astronomical objects including distant galaxies, planets, black holes and stars," said Chandra project scientist Dr. Martin C. Weisskopf of NASA's Marshall Space Flight Center in Huntsville, Ala. "In the last year alone, Chandra has generated the most sensitive or 'deepest' X-ray exposure ever made, shed new light on the planet Mars, and made several new discoveries involving supermassive black holes," added Weisskopf, who has dedicated nearly 30 years to the Chandra program. The deepest X-ray exposure, Chandra Deep Field North, captured for 23 days an area of the sky one-fifth the size of the full moon. Even though the faintest sources detected produced only one X-ray photon every four days, Chandra found more than 600 X-ray sources -- most of them supermassive black holes in galaxy centers. If the number of black holes seen in that area of the sky were typical, 300 million supermassive black holes would be detectable over the whole sky. In our own solar system, another Chandra image offered scientists their first look at X-rays from Mars . Not only did Chandra detect X-rays in the sparse upper atmosphere 750 miles above the planet, it also offered evidence for a faint halo of X-rays extending out 4,350 miles above the Martian surface. "In its fourth year of operation, Chandra continues to prove itself an engineering marvel," said Chandra Program Manager Keith Hefner at NASA's Marshall Center. "At its highest point, it travels one-third of the way to the Moon, yet it consistently delivers breathtaking results gleaned from millions, sometimes billions, of light years away." Some of Chandra's most intriguing discoveries involved black holes

Deconvolving the Nucleus of Centaurus A Using Chandra PSF Library

Science.gov (United States)

Karovska, Margarita

2000-01-01

Centaurus A (NGC 5128) is a giant early-type galaxy containing the nearest (at 3.5 Mpc) radio-bright Active Galactic Nucleus (AGN). Cen A was observed with the High Resolution Camera (HRC) on the Chandra X-ray Observatory on several occasions since the launch in July 1999. The high-angular resolution (less than 0.5 arcsecond) Chandra/HRC images reveal X ray multi-scale structures in this object with unprecedented detail and clarity, including the bright nucleus believed to be associated with a supermassive black hole. We explored the spatial extent of the Cen A nucleus using deconvolution techniques on the full resolution Chandra images. Model point spread functions (PSFs) were derived from the standard Chandra raytrace PSF library as well as unresolved point sources observed with Chandra. The deconvolved images show that the Cen A nucleus is resolved and asymmetric. We discuss several possible causes of this extended emission and of the asymmetries.

Chance and Chandra

Indian Academy of Sciences (India)

with inverse-square interparticle forces. The roles of ... ness fluctuations in the star fields of the Milky Way [1] and one on the inference of the distribution ... Chandra, however, argued for a cut-off at the mean interparticle distance, D ... the root of the difficulty with large impact parameters lies in the insistence upon Markovian.

Chandra Sees Remarkable Eclipse of Black Hole

Science.gov (United States)

2007-04-01

A remarkable eclipse of a supermassive black hole and the hot gas disk around it has been observed with NASA's Chandra X-ray Observatory. This eclipse has allowed two key predictions about the effects of supermassive black holes to be tested. Just as eclipses of the Sun and moon give astronomers rare opportunities to learn about those objects, an alignment in a nearby galaxy has provided a rare opportunity to investigate a supermassive black hole. Illustrations of Black Hole Eclipse Illustrations of Black Hole Eclipse The supermassive black hole is located in NGC 1365, a galaxy 60 million light years from Earth. It contains a so called active galactic nucleus, or AGN. Scientists believe that the black hole at the center of the AGN is fed by a steady stream of material, presumably in the form of a disk. Material just about to fall into a black hole should be heated to millions of degrees before passing over the event horizon, or point of no return. The disk of gas around the central black hole in NGC 1365 produces copious X-rays but is much too small to resolve directly with a telescope. However, the disk was eclipsed by an intervening cloud, so observation of the time taken for the disk to go in and out of eclipse allowed scientists to estimate the size of the disk. Black Hole Animation Black Hole Animation "For years we've been struggling to confirm the size of this X-ray structure," said Guido Risaliti of the Harvard-Smithsonian Center for Astrophysics (CfA) in Cambridge, Mass, and the Italian Institute of Astronomy (INAF). "This serendipitous eclipse enabled us to make this breakthrough." The Chandra team directly measured the size of the X-ray source as about seven times the distance between the Sun and the Earth. That means the source of X-rays is about 2 billion times smaller than the host galaxy and only about 10 times larger than the estimated size of the black hole's event horizon, consistent with theoretical predictions. Chandra X-ray Image of NGC 1365

Budhani, Dr Ramesh Chandra

Indian Academy of Sciences (India)

Budhani, Dr Ramesh Chandra Ph.D. (IIT, Delhi), FNASc, FNA. Date of birth: 3 February 1955. Specialization: Renewable Energy, Nanoscale Systems, Experimental Condensed Matter Physics, Superconductivity and Magnetism Address: Department of Physics, Lasers & Photonics, Indian Institute of Technology, Kanpur 208 ...

CIAO: CHANDRA/X-RAY DATA ANALYSIS FOR EVERYONE

Science.gov (United States)

McDowell, Jonathan; CIAO Team

2018-01-01

Eighteen years after the launch of Chandra, the archive is full of scientifically rich data and new observations continue. Improvements in recent years to the data analysis package CIAO (Chandra Interactive Analysis of Observations) and its extensive accompanying documentation make it easier for astronomers without a specialist background in high energy astrophysics to take advantage of this resource.The CXC supports hundreds of CIAO users around the world at all levels of training from high school and undergraduate students to the most experienced X-ray astronomers. In general, we strive to provide a software system which is easy for beginners, yet powerful for advanced users.Chandra data cover a range of instrument configurations and types of target (pointlike, extended and moving), requiring a flexible data analysis system. In addition to CIAO tools using the familiar FTOOLS/IRAF-style parameter interface, CIAO includes applications such as the Sherpa fitting engine which provide access to the data via Python scripting.In this poster we point prospective (and existing!) users to the high level Python scripts now provided to reprocess Chandra or other X-ray mission data, determine source fluxes and upper limits, and estimate backgrounds; and to the latest documentation including the CIAO Gallery, a new entry point featuring the system's different capabilities.This work has been supported by NASA under contract NAS 8-03060 to the Smithsonian Astrophysical Observatory for operation of the Chandra X-ray Center.

THE CHANDRA COSMOS LEGACY SURVEY: OPTICAL/IR IDENTIFICATIONS

International Nuclear Information System (INIS)

Marchesi, S.; Civano, F.; Urry, C. M.; Elvis, M.; Salvato, M.; Brusa, M.; Lanzuisi, G.; Vignali, C.; Comastri, A.; Gilli, R.; Zamorani, G.; Cappelluti, N.; Hasinger, G.; Miyaji, T.; Treister, E.; Allevato, V.; Finoguenov, A.; Cardamone, C.; Griffiths, R. E.; Karim, A.

2016-01-01

We present the catalog of optical and infrared counterparts of the Chandra  COSMOS-Legacy  Survey, a 4.6 Ms Chandra  program on the 2.2 deg 2 of the COSMOS field, combination of 56 new overlapping observations obtained in Cycle 14 with the previous C-COSMOS survey. In this Paper we report the i, K, and 3.6 μm identifications of the 2273 X-ray point sources detected in the new Cycle 14 observations. We use the likelihood ratio technique to derive the association of optical/infrared (IR) counterparts for 97% of the X-ray sources. We also update the information for the 1743 sources detected in C-COSMOS, using new K and 3.6 μm information not available when the C-COSMOS analysis was performed. The final catalog contains 4016 X-ray sources, 97% of which have an optical/IR counterpart and a photometric redshift, while ≃54% of the sources have a spectroscopic redshift. The full catalog, including spectroscopic and photometric redshifts and optical and X-ray properties described here in detail, is available online. We study several X-ray to optical (X/O) properties: with our large statistics we put better constraints on the X/O flux ratio locus, finding a shift toward faint optical magnitudes in both soft and hard X-ray band. We confirm the existence of a correlation between X/O and the the 2–10 keV luminosity for Type 2 sources. We extend to low luminosities the analysis of the correlation between the fraction of obscured AGNs and the hard band luminosity, finding a different behavior between the optically and X-ray classified obscured fraction

Lakhotia, Prof. Subhash Chandra

Indian Academy of Sciences (India)

Elected: 1994 Section: Animal Sciences. Lakhotia, Prof. Subhash Chandra Ph.D. (Calcutta), FNA, FNASc. Date of birth: 4 October 1945. Specialization: Ayurvedic Biology, Cytogenetics, Gene Expression, Stress Biology and Molecular Biology Address: INSA Senior Scientist, Department of Zoology, Banaras Hindu University ...

Chandra and JVLA Observations of HST Frontier Fields Cluster MACS J0717.5+3745

International Nuclear Information System (INIS)

Van Weeren, R. J.; Jones, C.; Forman, W. R.; Andrade-Santos, F.; Pearce, Connor J. J.; David, L.; Kraft, R. P.; Nulsen, P. E. J.; Ogrean, G. A.; Bonafede, A.; Brüggen, M.; Bulbul, E.; Clarke, T. E.; Churazov, E.; Dawson, W. A.; Donahue, M.; Goulding, A.; Mason, B.; Merten, J.; Mroczkowski, T.

2017-01-01

To investigate the relationship between thermal and non-thermal components in merger galaxy clusters, we present deep JVLA and Chandra observations of the HST Frontier Fields cluster MACS J0717.5+3745. The Chandra image shows a complex merger event, with at least four components belonging to different merging subclusters. Northwest of the cluster, ∼0.7 Mpc from the center, there is a ram-pressure-stripped core that appears to have traversed the densest parts of the cluster after entering the intracluster medium (ICM) from the direction of a galaxy filament to the southeast. We detect a density discontinuity north-northeast of this core, which we speculate is associated with a cold front. Our radio images reveal new details for the complex radio relic and radio halo in this cluster. In addition, we discover several new filamentary radio sources with sizes of 100–300 kpc. A few of these seem to be connected to the main radio relic, while others are either embedded within the radio halo or projected onto it. A narrow-angled-tailed (NAT) radio galaxy, a cluster member, is located at the center of the radio relic. The steep spectrum tails of this active galactic nucleus lead into the large radio relic where the radio spectrum flattens again. This morphological connection between the NAT radio galaxy and relic provides evidence for re-acceleration (revival) of fossil electrons. The presence of hot ≳20 keV ICM gas detected by Chandra near the relic location provides additional support for this re-acceleration scenario.

Chandra and JVLA Observations of HST Frontier Fields Cluster MACS J0717.5+3745

Energy Technology Data Exchange (ETDEWEB)

Van Weeren, R. J.; Jones, C.; Forman, W. R.; Andrade-Santos, F.; Pearce, Connor J. J.; David, L.; Kraft, R. P.; Nulsen, P. E. J. [Harvard-Smithsonian Center for Astrophysics, 60 Garden Street, Cambridge, MA 02138 (United States); Ogrean, G. A. [Department of Physics, Stanford University, 382 Via Pueblo Mall, Stanford, CA 94305-4060 (United States); Bonafede, A.; Brüggen, M. [Hamburger Sternwarte, Universität Hamburg, Gojenbergsweg 112, D-21029 Hamburg (Germany); Bulbul, E. [Kavli Institute for Astrophysics and Space Research, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, MA 02139 (United States); Clarke, T. E. [U.S. Naval Research Laboratory, 4555 Overlook Avenue SW, Washington, D.C. 20375 (United States); Churazov, E. [Max Planck Institute for Astrophysics, Karl-Schwarzschild-Str. 1, D-85741, Garching (Germany); Dawson, W. A. [Lawrence Livermore National Lab, 7000 East Avenue, Livermore, CA 94550 (United States); Donahue, M. [Department of Physics and Astronomy, Michigan State University, East Lansing, MI 48824 (United States); Goulding, A. [Department of Astrophysical Sciences, Princeton University, Princeton, NJ 08544 (United States); Mason, B. [National Radio Astronomy Observatory, 520 Edgemont Road, Charlottesville, VA 22903 (United States); Merten, J. [Department of Physics, University of Oxford, Keble Road, Oxford OX1 3RH (United Kingdom); Mroczkowski, T., E-mail: rvanweeren@cfa.harvard.edu [ESO—European Organization for Astronomical Research in the Southern Hemisphere, Karl-Schwarzschild-Str. 2, D-85748 Garching b. München (Germany); and others

2017-02-01

To investigate the relationship between thermal and non-thermal components in merger galaxy clusters, we present deep JVLA and Chandra observations of the HST Frontier Fields cluster MACS J0717.5+3745. The Chandra image shows a complex merger event, with at least four components belonging to different merging subclusters. Northwest of the cluster, ∼0.7 Mpc from the center, there is a ram-pressure-stripped core that appears to have traversed the densest parts of the cluster after entering the intracluster medium (ICM) from the direction of a galaxy filament to the southeast. We detect a density discontinuity north-northeast of this core, which we speculate is associated with a cold front. Our radio images reveal new details for the complex radio relic and radio halo in this cluster. In addition, we discover several new filamentary radio sources with sizes of 100–300 kpc. A few of these seem to be connected to the main radio relic, while others are either embedded within the radio halo or projected onto it. A narrow-angled-tailed (NAT) radio galaxy, a cluster member, is located at the center of the radio relic. The steep spectrum tails of this active galactic nucleus lead into the large radio relic where the radio spectrum flattens again. This morphological connection between the NAT radio galaxy and relic provides evidence for re-acceleration (revival) of fossil electrons. The presence of hot ≳20 keV ICM gas detected by Chandra near the relic location provides additional support for this re-acceleration scenario.

The Chandra Source Catalog: Processing and Infrastructure

Science.gov (United States)

Evans, Janet; Evans, Ian N.; Glotfelty, Kenny J.; Hain, Roger; Hall, Diane M.; Miller, Joseph B.; Plummer, David A.; Zografou, Panagoula; Primini, Francis A.; Anderson, Craig S.; Bonaventura, Nina R.; Chen, Judy C.; Davis, John E.; Doe, Stephen M.; Fabbiano, Giuseppina; Galle, Elizabeth C.; Gibbs, Danny G., II; Grier, John D.; Harbo, Peter N.; He, Xiang Qun (Helen); Houck, John C.; Karovska, Margarita; Kashyap, Vinay L.; Lauer, Jennifer; McCollough, Michael L.; McDowell, Jonathan C.; Mitschang, Arik W.; Morgan, Douglas L.; Mossman, Amy E.; Nichols, Joy S.; Nowak, Michael A.; Refsdal, Brian L.; Rots, Arnold H.; Siemiginowska, Aneta L.; Sundheim, Beth A.; Tibbetts, Michael S.; van Stone, David W.; Winkelman, Sherry L.

2009-09-01

Chandra Source Catalog processing recalibrates each observation using the latest available calibration data, and employs a wavelet-based source detection algorithm to identify all the X-ray sources in the field of view. Source properties are then extracted from each detected source that is a candidate for inclusion in the catalog. Catalog processing is completed by matching sources across multiple observations, merging common detections, and applying quality assurance checks. The Chandra Source Catalog processing system shares a common processing infrastructure and utilizes much of the functionality that is built into the Standard Data Processing (SDP) pipeline system that provides calibrated Chandra data to end-users. Other key components of the catalog processing system have been assembled from the portable CIAO data analysis package. Minimal new software tool development has been required to support the science algorithms needed for catalog production. Since processing pipelines must be instantiated for each detected source, the number of pipelines that are run during catalog construction is a factor of order 100 times larger than for SDP. The increased computational load, and inherent parallel nature of the processing, is handled by distributing the workload across a multi-node Beowulf cluster. Modifications to the SDP automated processing application to support catalog processing, and extensions to Chandra Data Archive software to ingest and retrieve catalog products, complete the upgrades to the infrastructure to support catalog processing.

Thakur, Dr Vikram Chandra

Indian Academy of Sciences (India)

Home; Fellowship. Fellow Profile. Elected: 1991 Section: Earth & Planetary Sciences. Thakur, Dr Vikram Chandra Ph.D. (London). Date of birth: 15 January 1940. Specialization: Structural Geology, Tectonics of Himalayan Geology and Active Tectonics Address: 9/12 (Lane 9), Ashirwad Eclave, Dehra Dun 248 001, ...

Chaturvedi, Prof. Umesh Chandra

Indian Academy of Sciences (India)

Chaturvedi, Prof. Umesh Chandra M.D. (Lucknow), FRC Path. (London), FAMS, FNA, FNASc, FAAM(USA). Date of birth: 2 March 1939. Specialization: Medical Microbiology, Virology and Immunology Address: 201, Annapurna Apartments, No. 1, Bishop Rocky Street, Faizabad Road, Lucknow 226 007, U.P.. Contact:

The Chandra Source Catalog: Background Determination and Source Detection

Science.gov (United States)

McCollough, Michael; Rots, Arnold; Primini, Francis A.; Evans, Ian N.; Glotfelty, Kenny J.; Hain, Roger; Anderson, Craig S.; Bonaventura, Nina R.; Chen, Judy C.; Davis, John E.; Doe, Stephen M.; Evans, Janet D.; Fabbiano, Giuseppina; Galle, Elizabeth C.; Danny G. Gibbs, II; Grier, John D.; Hall, Diane M.; Harbo, Peter N.; He, Xiang Qun (Helen); Houck, John C.; Karovska, Margarita; Kashyap, Vinay L.; Lauer, Jennifer; McCollough, Michael L.; McDowell, Jonathan C.; Miller, Joseph B.; Mitschang, Arik W.; Morgan, Douglas L.; Mossman, Amy E.; Nichols, Joy S.; Nowak, Michael A.; Plummer, David A.; Refsdal, Brian L.; Siemiginowska, Aneta L.; Sundheim, Beth A.; Tibbetts, Michael S.; van Stone, David W.; Winkelman, Sherry L.; Zografou, Panagoula

2009-09-01

The Chandra Source Catalog (CSC) is a major project in which all of the pointed imaging observations taken by the Chandra X-Ray Observatory are used to generate one of the most extensive X-ray source catalog produced to date. Early in the development of the CSC it was recognized that the ability to estimate local background levels in an automated fashion would be critical for essential CSC tasks such as source detection, photometry, sensitivity estimates, and source characterization. We present a discussion of how such background maps are created directly from the Chandra data and how they are used in source detection. The general background for Chandra observations is rather smoothly varying, containing only low spatial frequency components. However, in the case of ACIS data, a high spatial frequency component is added that is due to the readout streaks of the CCD chips. We discuss how these components can be estimated reliably using the Chandra data and what limitations and caveats should be considered in their use. We will discuss the source detection algorithm used for the CSC and the effects of the background images on the detection results. We will also touch on some the Catalog Inclusion and Quality Assurance criteria applied to the source detection results. This work is supported by NASA contract NAS8-03060 (CXC).

ASA's Chandra Neon Discovery Solves Solar Paradox

Science.gov (United States)

2005-07-01

NASA's Chandra X-ray Observatory survey of nearby sun-like stars suggests there is nearly three times more neon in the sun and local universe than previously believed. If true, this would solve a critical problem with understanding how the sun works. "We use the sun to test how well we understand stars and, to some extent, the rest of the universe," said Jeremy Drake of the Harvard-Smithsonian Center for Astrophysics in Cambridge, Mass. "But in order to understand the sun, we need to know exactly what it is made of," he added. It is not well known how much neon the sun contains. This is critical information for creating theoretical models of the sun. Neon atoms, along with carbon, oxygen and nitrogen, play an important role in how quickly energy flows from nuclear reactions in the sun's core to its edge, where it then radiates into space. Chandra X-ray Spectrum of II Pegasi Chandra X-ray Spectrum of II Pegasi The rate of this energy flow determines the location and size of a crucial stellar region called the convection zone. The zone extends from near the sun's surface inward approximately 125,000 miles. The zone is where the gas undergoes a rolling, convective motion much like the unstable air in a thunderstorm. "This turbulent gas has an extremely important job, because nearly all of the energy emitted at the surface of the sun is transported there by convection," Drake said. The accepted amount of neon in the sun has led to a paradox. The predicted location and size of the solar convection zone disagree with those deduced from solar oscillations. Solar oscillations is a technique astronomers previously relied on to probe the sun's interior. Several scientists have noted the problem could be fixed if the abundance of neon is in fact about three times larger than currently accepted. Attempts to measure the precise amount of neon in the Sun have been frustrated by a quirk of nature; neon atoms in the Sun give off no signatures in visible light. However, in a gas

Chandra Catches "Piranha" Black Holes

Science.gov (United States)

2007-07-01

Supermassive black holes have been discovered to grow more rapidly in young galaxy clusters, according to new results from NASA's Chandra X-ray Observatory. These "fast-track" supermassive black holes can have a big influence on the galaxies and clusters that they live in. Using Chandra, scientists surveyed a sample of clusters and counted the fraction of galaxies with rapidly growing supermassive black holes, known as active galactic nuclei (or AGN). The data show, for the first time, that younger, more distant galaxy clusters contained far more AGN than older, nearby ones. Galaxy clusters are some of the largest structures in the Universe, consisting of many individual galaxies, a few of which contain AGN. Earlier in the history of the universe, these galaxies contained a lot more gas for star formation and black hole growth than galaxies in clusters do today. This fuel allows the young cluster black holes to grow much more rapidly than their counterparts in nearby clusters. Illustration of Active Galactic Nucleus Illustration of Active Galactic Nucleus "The black holes in these early clusters are like piranha in a very well-fed aquarium," said Jason Eastman of Ohio State University (OSU) and first author of this study. "It's not that they beat out each other for food, rather there was so much that all of the piranha were able to really thrive and grow quickly." The team used Chandra to determine the fraction of AGN in four different galaxy clusters at large distances, when the Universe was about 58% of its current age. Then they compared this value to the fraction found in more nearby clusters, those about 82% of the Universe's current age. The result was the more distant clusters contained about 20 times more AGN than the less distant sample. AGN outside clusters are also more common when the Universe is younger, but only by factors of two or three over the same age span. "It's been predicted that there would be fast-track black holes in clusters, but we never

THE CHANDRA COSMOS LEGACY SURVEY: OPTICAL/IR IDENTIFICATIONS

Energy Technology Data Exchange (ETDEWEB)

Marchesi, S.; Civano, F.; Urry, C. M. [Yale Center for Astronomy and Astrophysics, 260 Whitney Avenue, New Haven, CT 06520 (United States); Elvis, M. [Harvard-Smithsonian Center for Astrophysics, 60 Garden Street, Cambridge, MA 02138 (United States); Salvato, M. [Max-Planck-Institut für extraterrestrische Physik, Giessenbachstrasse 1, D-85748 Garching bei München (Germany); Brusa, M.; Lanzuisi, G.; Vignali, C. [Dipartimento di Fisica e Astronomia, Università di Bologna, viale Berti Pichat 6/2, I-40127 Bologna (Italy); Comastri, A.; Gilli, R.; Zamorani, G.; Cappelluti, N. [INAF—Osservatorio Astronomico di Bologna, via Ranzani 1, I-40127 Bologna (Italy); Hasinger, G. [Institute for Astronomy, 2680 Woodlawn Drive, University of Hawaii, Honolulu, HI 96822 (United States); Miyaji, T. [Instituto de Astronomía sede Ensenada, Universidad Nacional Autónoma de México, Km. 103, Carret. Tijunana-Ensenada, Ensenada, BC (Mexico); Treister, E. [Universidad de Concepción, Departamento de Astronomía, Casilla 160-C, Concepción (Chile); Allevato, V.; Finoguenov, A. [Department of Physics, University of Helsinki, Gustaf Hällströmin katu 2a, FI-00014 Helsinki (Finland); Cardamone, C. [Department of Science, Wheelock College, Boston, MA 02215 (United States); Griffiths, R. E. [Physics and Astronomy Dept., Natural Sciences Division, University of Hawaii at Hilo, 200 W. Kawili Street, Hilo, HI 96720 (United States); Karim, A. [Argelander-Institut für Astronomie, Universität Bonn, Auf dem Hügel 71, D-53121 Bonn (Germany); and others

2016-01-20

We present the catalog of optical and infrared counterparts of the Chandra  COSMOS-Legacy  Survey, a 4.6 Ms Chandra  program on the 2.2 deg{sup 2} of the COSMOS field, combination of 56 new overlapping observations obtained in Cycle 14 with the previous C-COSMOS survey. In this Paper we report the i, K, and 3.6 μm identifications of the 2273 X-ray point sources detected in the new Cycle 14 observations. We use the likelihood ratio technique to derive the association of optical/infrared (IR) counterparts for 97% of the X-ray sources. We also update the information for the 1743 sources detected in C-COSMOS, using new K and 3.6 μm information not available when the C-COSMOS analysis was performed. The final catalog contains 4016 X-ray sources, 97% of which have an optical/IR counterpart and a photometric redshift, while ≃54% of the sources have a spectroscopic redshift. The full catalog, including spectroscopic and photometric redshifts and optical and X-ray properties described here in detail, is available online. We study several X-ray to optical (X/O) properties: with our large statistics we put better constraints on the X/O flux ratio locus, finding a shift toward faint optical magnitudes in both soft and hard X-ray band. We confirm the existence of a correlation between X/O and the the 2–10 keV luminosity for Type 2 sources. We extend to low luminosities the analysis of the correlation between the fraction of obscured AGNs and the hard band luminosity, finding a different behavior between the optically and X-ray classified obscured fraction.

Chandra Early Type Galaxy Atals

Science.gov (United States)

Kim, Dong-Woo; Anderson, Craig; Burke, Douglas J.; Fabbiano, Giuseppina; Fruscione, Antonella; Lauer, Jennifer; McCollough, Michael; Morgan, Douglas; Mossman, Amy; O'Sullivan, Ewan; Paggi, Alessandro; Vrtilek, Saeqa Dil; Trinchieri, Ginevra

2017-08-01

The hot gas in early type galaxies (ETGs) plays a crucial role in understanding their formation and evolution. As the hot gas is often extended to the outskirts beyond the optical size, the large scale structural features identified by Chandra (including jets, cavities, cold fronts, filaments and tails) point to key evolutionary mechanisms, e.g., AGN feedback, merging history, accretion, stripping and star formation and its quenching. We have systematically analyzed the archival Chandra data of ~100 ETGs to study the hot ISM. We produce the uniformly derived data products with spatially resolved spectral information and will make them accessible via a public web site. With 2D spectral infomation, we further discuss gas morphology, scaling relations, X-ray based mass profiles and their implications related to various physical mechanisms (e.g., stellar and AGN feedback).

The End of Days -- Chandra Catches X-ray Glow From Supernova

Science.gov (United States)

1999-12-01

Through a combination of serendipity and skill, scientists have used NASA's Chandra X-ray Observatory to capture a rare glimpse of X-radiation from the early phases of a supernova, one of the most violent events in nature. Although more than a thousand supernovas have been observed by optical astronomers, the early X-ray glow from the explosions has been detected in less than a dozen cases. The Chandra observations were made under the direction of a team of scientists from the Massachusetts Institute of Technology (MIT) in Cambridge, led by Walter Lewin and his graduate student, Derek Fox. When combined with simultaneous observations by radio and optical telescopes, the X-ray observations tell about the thickness of the shell that was blown off, its density, its speed, and how much material was shed by the star before it exploded. Chandra observed an X-ray glow from SN1999em with the total power of 50,000 suns. Ten days later it observed the supernova for another nine hours, and found that the X rays had faded to half their previous intensity. The optical luminosity, which had the brightness of 200 million suns, had faded somewhat less. No radio emission was detected at any time. With this information, the MIT group and their colleagues are already piecing together a picture of the catastrophic explosion. Observations by optical astronomers showed that SN1999em was a Type II supernova produced by the collapse of the core of a star ten or more times as massive as the Sun. The intense heat generated in the collapse produces a cataclysmic rebound that sends high speed debris flying outward at speeds in excess of 20 million miles per hour. The debris crashes into matter shed by the former star before the explosion. This awesome collision generates shock waves that heat expanding debris to three million degrees. The X-ray glow from this hot gas was detected by Chandra and gives astrophysicists a better understanding of the dynamics of the explosion, as well as the

TRW Ships NASA's Chandra X-ray Observatory To Kennedy Space Center

Science.gov (United States)

1999-04-01

Two U.S. Air Force C-5 Galaxy transport planes carrying the observatory and its ground support equipment landed at Kennedy's Space Shuttle Landing Facility at 2:40 p.m. EST this afternoon. REDONDO BEACH, CA.--(Business Wire)--Feb. 4, 1999--TRW has shipped NASA's Chandra X-ray Observatory ("Chandra") to the Kennedy Space Center (KSC), in Florida, in preparation for a Space Shuttle launch later this year. The 45-foot-tall, 5-ton science satellite will provide astronomers with new information on supernova remnants, the surroundings of black holes, and other celestial phenomena that produce vast quantities of X-rays. Cradled safely in the cargo hold of a tractor-trailer rig called the Space Cargo Transportation System (SCTS), NASA's newest space telescope was ferried on Feb. 4 from Los Angeles International Airport to KSC aboard an Air Force C-5 Galaxy transporter. The SCTS, an Air Force container, closely resembles the size and shape of the Shuttle cargo bay. Over the next few months, Chandra will undergo final tests at KSC and be mated to a Boeing-provided Inertial Upper Stage for launch aboard Space Shuttle Columbia. A launch date for the Space Shuttle STS-93 mission is expected to be announced later this week. The third in NASA's family of Great Observatories that includes the Hubble Space Telescope and the TRW-built Compton Gamma Ray observatory, Chandra will use the world's most powerful X-ray telescope to allow scientists to "see" and monitor cosmic events that are invisible to conventional optical telescopes. Chandra's X-ray images will yield new insight into celestial phenomena such as the temperature and extent of gas clouds that comprise clusters of galaxies and the superheating of gas and dust particles as they swirl into black holes. A TRW-led team that includes the Eastman Kodak Co., Raytheon Optical Systems Inc., and Ball Aerospace & Technologies Corp. designed and built the Chandra X-ray Observatory for NASA's Marshall Space Flight Center. The

Cosmological constraints from Chandra observations of galaxy clusters.

Science.gov (United States)

Allen, Steven W

2002-09-15

Chandra observations of rich, relaxed galaxy clusters allow the properties of the X-ray gas and the total gravitating mass to be determined precisely. Here, we present results for a sample of the most X-ray luminous, dynamically relaxed clusters known. We show that the Chandra data and independent gravitational lensing studies provide consistent answers on the mass distributions in the clusters. The mass profiles exhibit a form in good agreement with the predictions from numerical simulations. Combining Chandra results on the X-ray gas mass fractions in the clusters with independent measurements of the Hubble constant and the mean baryonic matter density in the Universe, we obtain a tight constraint on the mean total matter density of the Universe, Omega(m), and an interesting constraint on the cosmological constant, Omega(Lambda). We also describe the 'virial relations' linking the masses, X-ray temperatures and luminosities of galaxy clusters. These relations provide a key step in linking the observed number density and spatial distribution of clusters to the predictions from cosmological models. The Chandra data confirm the presence of a systematic offset of ca. 40% between the normalization of the observed mass-temperature relation and the predictions from standard simulations. This finding leads to a significant revision of the best-fit value of sigma(8) inferred from the observed temperature and luminosity functions of clusters.

INNOVATIONS IN THE ANALYSIS OF CHANDRA-ACIS OBSERVATIONS

International Nuclear Information System (INIS)

Broos, Patrick S.; Townsley, Leisa K.; Feigelson, Eric D.; Getman, Konstantin V.; Garmire, Gordon P.; Bauer, Franz E.

2010-01-01

As members of the instrument team for the Advanced CCD Imaging Spectrometer (ACIS) on NASA's Chandra X-ray Observatory and as Chandra General Observers, we have developed a wide variety of data analysis methods that we believe are useful to the Chandra community, and have constructed a significant body of publicly available software (the ACIS Extract package) addressing important ACIS data and science analysis tasks. This paper seeks to describe these data analysis methods for two purposes: to document the data analysis work performed in our own science projects and to help other ACIS observers judge whether these methods may be useful in their own projects (regardless of what tools and procedures they choose to implement those methods). The ACIS data analysis recommendations we offer here address much of the workflow in a typical ACIS project, including data preparation, point source detection via both wavelet decomposition and image reconstruction, masking point sources, identification of diffuse structures, event extraction for both point and diffuse sources, merging extractions from multiple observations, nonparametric broadband photometry, analysis of low-count spectra, and automation of these tasks. Many of the innovations presented here arise from several, often interwoven, complications that are found in many Chandra projects: large numbers of point sources (hundreds to several thousand), faint point sources, misaligned multiple observations of an astronomical field, point source crowding, and scientifically relevant diffuse emission.

Chandra's Darkest Bright Star: not so Dark after All?

Science.gov (United States)

Ayres, Thomas R.

2008-11-01

The Chandra High Resolution camera (HRC) has obtained numerous short exposures of the ultraviolet (UV)-bright star Vega (α Lyrae; HD 172167: A0 V), to calibrate the response of the detector to out-of-band (non-X-ray) radiation. A new analysis uncovered a stronger "blue leak" in the imaging section (HRC-I) than reported in an earlier study of Vega based on a subset of the pointings. The higher count rate—a factor of nearly 2 above prelaunch estimates—raised the possibility that genuine coronal X-rays might lurk among the out-of-band events. Exploiting the broader point-spread function of the UV leak compared with soft X-rays identified an excess of counts centered on the target, technically at 3σ significance. A number of uncertainties, however, prevent a clear declaration of a Vegan corona. A more secure result would be within reach of a deep uninterrupted HRC-I pointing.

Chandra Discovers Light Echo from the Milky Way's Black Hole

Science.gov (United States)

2007-01-01

Like cold case investigators, astronomers have used NASA's Chandra X-ray Observatory to uncover evidence of a powerful outburst from the giant black hole at the Milky Way's center. A light echo was produced when X-ray light generated by gas falling into the Milky Way's supermassive black hole, known as Sagittarius A* (pronounced "A-star"), was reflected off gas clouds near the black hole. While the primary X-rays from the outburst would have reached Earth about 50 years ago, the reflected X-rays took a longer path and arrived in time to be recorded by Chandra. Variability in Chandra Images of Light Echo Variability in Chandra Images of Light Echo "This dramatic event happened before we had satellites in space that could detect it," said Michael Muno of the California Institute of Technology in Pasadena. "So, it's remarkable that we can use Chandra to dig into the past and see this monster black hole's capacity for destruction." Previously, scientists have used Chandra to directly detect smaller and more recent outbursts from the black hole. This latest outburst revealed by the X-ray echo was about 1,000 times brighter and lasted well over 1,000 times longer than any of the recent outbursts observed by Chandra. Theory predicts that an outburst from Sagittarius A* would cause X-ray emission from the clouds to vary in both intensity and shape. Muno and his team found these changes for the first time, thus ruling out other interpretations. The latest results corroborate other independent, but indirect, evidence for light echoes generated by the black hole in the more distant past. Illustrations of Light Echo Illustrations of Light Echo Scientists have long known that Sagittarius A*, with a mass of about 3 million suns, lurked at the center for Milky Way. However, the black hole is incredibly faint at all wavelengths, especially in X-rays. "This faintness implies that stars and gas rarely get close enough to the black hole to be in any danger," said co-author Frederick

The Chandra Source Catalog 2.0: Calibrations

Science.gov (United States)

Graessle, Dale E.; Evans, Ian N.; Rots, Arnold H.; Allen, Christopher E.; Anderson, Craig S.; Budynkiewicz, Jamie A.; Burke, Douglas; Chen, Judy C.; Civano, Francesca Maria; D'Abrusco, Raffaele; Doe, Stephen M.; Evans, Janet D.; Fabbiano, Giuseppina; Gibbs, Danny G., II; Glotfelty, Kenny J.; Grier, John D.; Hain, Roger; Hall, Diane M.; Harbo, Peter N.; Houck, John C.; Lauer, Jennifer L.; Laurino, Omar; Lee, Nicholas P.; Martínez-Galarza, Juan Rafael; McCollough, Michael L.; McDowell, Jonathan C.; Miller, Joseph; McLaughlin, Warren; Morgan, Douglas L.; Mossman, Amy E.; Nguyen, Dan T.; Nichols, Joy S.; Nowak, Michael A.; Paxson, Charles; Plummer, David A.; Primini, Francis Anthony; Siemiginowska, Aneta; Sundheim, Beth A.; Tibbetts, Michael; Van Stone, David W.; Zografou, Panagoula

2018-01-01

Among the many enhancements implemented for the release of Chandra Source Catalog (CSC) 2.0 are improvements in the processing calibration database (CalDB). We have included a thorough overhaul of the CalDB software used in the processing. The software system upgrade, called "CalDB version 4," allows for a more rational and consistent specification of flight configurations and calibration boundary conditions. Numerous improvements in the specific calibrations applied have also been added. Chandra's radiometric and detector response calibrations vary considerably with time, detector operating temperature, and position on the detector. The CalDB has been enhanced to provide the best calibrations possible to each observation over the fifteen-year period included in CSC 2.0. Calibration updates include an improved ACIS contamination model, as well as updated time-varying gain (i.e., photon energy) and quantum efficiency maps for ACIS and HRC-I. Additionally, improved corrections for the ACIS quantum efficiency losses due to CCD charge transfer inefficiency (CTI) have been added for each of the ten ACIS detectors. These CTI corrections are now time and temperature-dependent, allowing ACIS to maintain a 0.3% energy calibration accuracy over the 0.5-7.0 keV range for any ACIS source in the catalog. Radiometric calibration (effective area) accuracy is estimated at ~4% over that range. We include a few examples where improvements in the Chandra CalDB allow for improved data reduction and modeling for the new CSC.This work has been supported by NASA under contract NAS 8-03060 to the Smithsonian Astrophysical Observatory for operation of the Chandra X-ray Center.

CHANDRA OBSERVATIONS OF SN 1987A: THE SOFT X-RAY LIGHT CURVE REVISITED

Energy Technology Data Exchange (ETDEWEB)

Helder, E. A.; Broos, P. S.; Burrows, D. N. [Department of Astronomy and Astrophysics, The Pennsylvania State University, 525 Davey Laboratory, University Park, PA 16802 (United States); Dewey, D. [MIT Kavli Institute, Cambridge, MA 02139 (United States); Dwek, E. [Observational Cosmology Laboratory, Code 665, NASA Goddard Space Flight Center, Greenbelt, MD 20771 (United States); McCray, R. [JILA, University of Colorado and NIST, 440 UCB, Boulder, CO 80309 (United States); Park, S. [Department of Physics, University of Texas at Arlington, Box 19059, Arlington, TX 76019 (United States); Racusin, J. L. [NASA, Goddard Space Flight Center, Code 661, Greenbelt, MD 20771 (United States); Zhekov, S. A. [Space Research and Technology Institute, Akad. G. Bonchev str., bl.1, Sofia 1113 (Bulgaria)

2013-02-10

We report on the present stage of SN 1987A as observed by the Chandra X-Ray Observatory. We reanalyze published Chandra observations and add three more epochs of Chandra data to get a consistent picture of the evolution of the X-ray fluxes in several energy bands. We discuss the implications of several calibration issues for Chandra data. Using the most recent Chandra calibration files, we find that the 0.5-2.0 keV band fluxes of SN 1987A have increased by {approx}6 Multiplication-Sign 10{sup -13} erg s{sup -1} cm{sup -2} per year since 2009. This is in contrast with our previous result that the 0.5-2.0 keV light curve showed a sudden flattening in 2009. Based on our new analysis, we conclude that the forward shock is still in full interaction with the equatorial ring.

Chandra Discovers X-Ray Ring Around Cosmic Powerhouse in Crab Nebula

Science.gov (United States)

1999-09-01

After barely two months in space, NASA's Chandra X-ray Observatory has taken a stunning image of the Crab Nebula, the spectacular remains of a stellar explosion, and has revealed something never seen before: a brilliant ring around the nebula's heart. Combined with observations from the Hubble Space Telescope, the image provides important clues to the puzzle of how the cosmic "generator," a pulsing neutron star, energizes the nebula, which still glows brightly almost 1,000 years after the explosion. "The inner ring is unique," said Professor Jeff Hester of Arizona State University, Tempe, AZ. "It has never been seen before, and it should tell us a lot about how the energy from the pulsar gets into the nebula. It's like finding the transmission lines between the power plant and the light bulb." Professor Mal Ruderman of Columbia University, New York, NY, agreed. "The X-rays Chandra sees are the best tracer of where the energy is. With images such as these, we can directly diagnose what is going on." What is going on, according to Dr. Martin Weisskopf, Chandra Project Scientist from NASA's Marshall Space Flight Center, Huntsville, AL, is awesome. "The Crab pulsar is accelerating particles up to the speed of light and flinging them out into interstellar space at an incredible rate." The image shows tilted rings or waves of high-energy particles that appear to have been flung outward over the distance of a light year from the central star, and high-energy jets of particles blasting away from the neutron star in a direction perpendicular to the spiral. Hubble Space Telescope images have shown moving knots and wisps around the neutron star, and previous X-ray images have shown the outer parts of the jet and hinted at the ring structure. With Chandra's exceptional resolution, the jet can be traced all the way in to the neutron star, and the ring pattern clearly appears. The image was made with Chandra's Advanced CCD Imaging Spectrometer and High Energy Transmission

Black Hole Paradox Solved By NASA's Chandra

Science.gov (United States)

2006-06-01

Black holes are lighting up the Universe, and now astronomers may finally know how. New data from NASA's Chandra X-ray Observatory show for the first time that powerful magnetic fields are the key to these brilliant and startling light shows. It is estimated that up to a quarter of the total radiation in the Universe emitted since the Big Bang comes from material falling towards supermassive black holes, including those powering quasars, the brightest known objects. For decades, scientists have struggled to understand how black holes, the darkest objects in the Universe, can be responsible for such prodigious amounts of radiation. Animation of a Black Hole Pulling Matter from Companion Star Animation of a Black Hole Pulling Matter from Companion Star New X-ray data from Chandra give the first clear explanation for what drives this process: magnetic fields. Chandra observed a black hole system in our galaxy, known as GRO J1655-40 (J1655, for short), where a black hole was pulling material from a companion star into a disk. "By intergalactic standards J1655 is in our backyard, so we can use it as a scale model to understand how all black holes work, including the monsters found in quasars," said Jon M. Miller of the University of Michigan, Ann Arbor, whose paper on these results appears in this week's issue of Nature. Gravity alone is not enough to cause gas in a disk around a black hole to lose energy and fall onto the black hole at the rates required by observations. The gas must lose some of its orbital angular momentum, either through friction or a wind, before it can spiral inward. Without such effects, matter could remain in orbit around a black hole for a very long time. Illustration of Magnetic Fields in GRO J1655-40 Illustration of Magnetic Fields in GRO J1655-40 Scientists have long thought that magnetic turbulence could generate friction in a gaseous disk and drive a wind from the disk that carries angular momentum outward allowing the gas to fall inward

Chandra Adds to Story of the Way We Were

Science.gov (United States)

2003-05-01

Data from NASA's Chandra X-ray Observatory have enabled astronomers to use a new way to determine if a young star is surrounded by a planet-forming disk like our early Sun. These results suggest that disks around young stars can evolve rapidly to form planets, or they can be disrupted by close encounters with other stars. Chandra observed two young star systems, TW Hydrae and HD 98800, both of which are in the TW Hydrae Association, a loose cluster of 10 million-year-old stars. Observations at infrared and other wavelengths have shown that several stars in the TW Hydrae Association are surrounded by disks of dust and gas. At a distance of about 180 light years from Earth, these systems are among the nearest analogs to the early solar nebula from which Earth formed. "X-rays give us an excellent new way to probe the disks around stars," said Joel Kastner of the Rochester Institute of Technology in Rochester, NY during a press conference today in Nashville, Tenn. at a meeting of the American Astronomical Society. "They can tell us whether a disk is very near to its parent star and dumping matter onto it, or whether such activity has ceased to be important. In the latter case, presumably the disk has been assimilated into larger bodies - perhaps planets--or disrupted." TW Hydrae and HD 98800A Chandra 0th Order Image of HD98800 Kastner and his colleagues found examples of each type of behavior in their study. One star, TW Hydrae, namesake of the TW Hydrae Association, exhibited features in its X-ray spectrum that provide strong, new evidence that matter is accreting onto the star from a circumstellar disk. They concluded that matter is guided by the star's magnetic field onto one or more hot spots on the surface of the star. In contrast, Chandra observations of the young multiple star system HD 98800 revealed that its brightest star, HD 98800A, is producing X-rays much as the Sun does, from a hot upper atmosphere or corona. HD 98800 is a complex multiple-star system

Chandra Captures Flare From Brown Dwarf

Science.gov (United States)

2000-07-01

The first flare ever seen from a brown dwarf, or failed star, was detected by NASA's Chandra X-ray Observatory. The bright X-ray flare has implications for understanding the explosive activity and origin of magnetic fields of extremely low mass stars. Chandra detected no X-rays at all from LP 944-20 for the first nine hours of a twelve hour observation, then the source flared dramatically before it faded away over the next two hours. "We were shocked," said Dr. Robert Rutledge of the California Institute of Technology in Pasadena, the lead author on the discovery paper to appear in the July 20 issue of Astrophysical Journal Letters. "We didn't expect to see flaring from such a lightweight object. This is really the 'mouse that roared.'" Chandra LP 944-20 X-ray Image Press Image and Caption The energy emitted in the brown dwarf flare was comparable to a small solar flare, and was a billion times greater than observed X-ray flares from Jupiter. The flaring energy is believed to come from a twisted magnetic field. "This is the strongest evidence yet that brown dwarfs and possibly young giant planets have magnetic fields, and that a large amount of energy can be released in a flare," said Dr. Eduardo Martin, also of Caltech and a member of the team. Professor Gibor Basri of the University of California, Berkeley, the principal investigator for this observation, speculated that the flare "could have its origin in the turbulent magnetized hot material beneath the surface of the brown dwarf. A sub-surface flare could heat the atmosphere, allowing currents to flow and give rise to the X-ray flare -- like a stroke of lightning." LP 944-20 is about 500 million years old and has a mass that is about 60 times that of Jupiter, or 6 percent that of the Sun. Its diameter is about one-tenth that of the Sun and it has a rotation period of less than five hours. Located in the constellation Fornax in the southern skies, LP 944-20 is one of the best studied brown dwarfs because it is

Patel, Prof. Chandra Kumar Naranbhai

Indian Academy of Sciences (India)

Elected: 1995 Honorary. Patel, Prof. Chandra Kumar Naranbhai. Date of birth: 2 July 1938. Address: President & CEO, Pranalytica Inc., 1101, Colorado Avenue, Santa Monica, CA 90401, U.S.A.. Contact: Office: (+1-310) 458 0808. Residence: (+1-310) 471 6505. Fax: (+1-310) 458 0171. Email: patel@pranalytica.com.

Chandra High Resolution Imaging of NGC 1365 and NGC 4151

Science.gov (United States)

Wang, Junfeng; Fabbiano, G.; Elvis, M.; Risaliti, G.; Karovska, M.; Zezas, A.; Mazzarella, J. M.; Lord, S.; Howell, J. H.; Mundell, C. G.

2010-07-01

We present Chandra high resolution imaging of the circumnuclear regions of two nearby active galaxies, namely the starburst/AGN composite Seyfert 1.8 NGC 1365 and the archetypal Seyfert 1 NGC 4151. In NGC 1365, the X-ray morphology shows a biconical soft X-ray-emission region extending ~5 kpc in projection from the nucleus, coincident with the optical high-excitation outflows. Chandra HRC imaging of the NGC 4151 nucleus resolves X-ray emission from the 4 arcsec radio jet and the narrow line region (NLR) clouds. Our results demonstrate the unique power of spatially resolved spectroscopy with Chandra, and support previous claims that frequent jet-ISM interaction may explain why jets in Seyfert galaxies appear small, slow, and thermally dominated.

Tracing the accretion history of supermassive black holes through X-ray variability: results from the ChandraDeep Field-South

Science.gov (United States)

Paolillo, M.; Papadakis, I.; Brandt, W. N.; Luo, B.; Xue, Y. Q.; Tozzi, P.; Shemmer, O.; Allevato, V.; Bauer, F. E.; Comastri, A.; Gilli, R.; Koekemoer, A. M.; Liu, T.; Vignali, C.; Vito, F.; Yang, G.; Wang, J. X.; Zheng, X. C.

2017-11-01

We study the X-ray variability properties of distant active galactic nuclei (AGNs) in the ChandraDeep Field-South region over 17 yr, up to z ˜ 4, and compare them with those predicted by models based on local samples. We use the results of Monte Carlo simulations to account for the biases introduced by the discontinuous sampling and the low-count regime. We confirm that variability is a ubiquitous property of AGNs, with no clear dependence on the density of the environment. The variability properties of high-z AGNs, over different temporal time-scales, are most consistent with a power spectral density (PSD) described by a broken (or bending) power law, similar to nearby AGNs. We confirm the presence of an anticorrelation between luminosity and variability, resulting from the dependence of variability on black hole (BH) mass and accretion rate. We explore different models, finding that our acceptable solutions predict that BH mass influences the value of the PSD break frequency, while the Eddington ratio λEdd affects the PSD break frequency and, possibly, the PSD amplitude as well. We derive the evolution of the average λEdd as a function of redshift, finding results in agreement with measurements based on different estimators. The large statistical uncertainties make our results consistent with a constant Eddington ratio, although one of our models suggest a possible increase of λEdd with lookback time up to z ˜ 2-3. We conclude that variability is a viable mean to trace the accretion history of supermassive BHs, whose usefulness will increase with future, wide-field/large effective area X-ray missions.

NARROW-LINE X-RAY-SELECTED GALAXIES IN THE CHANDRA -COSMOS FIELD. I. OPTICAL SPECTROSCOPIC CATALOG

Energy Technology Data Exchange (ETDEWEB)

Pons, E.; Watson, M. G. [University of Leicester, Leicester (United Kingdom); Elvis, M.; Civano, F. [Harvard-Smithsonian Center for Astrophysics, Cambridge, MA (United States)

2016-04-20

The COSMOS survey is a large and deep survey with multiwavelength observations of sources from X-rays to the UV, allowing an extensive study of their properties. The central 0.9 deg{sup 2} of the COSMOS field have been observed by Chandra with a sensitivity up to 1.9 × 10{sup −16} erg cm{sup −2} s{sup −1} in the full (0.5–10 keV) band. Photometric and spectroscopic identification of the Chandra -COSMOS (C-COSMOS) sources is available from several catalogs and campaigns. Despite the fact that the C-COSMOS galaxies have a reliable spectroscopic redshift in addition to a spectroscopic classification, the emission-line properties of this sample have not yet been measured. We present here the creation of an emission-line catalog of 453 narrow-line sources from the C-COSMOS spectroscopic sample. We have performed spectral fitting for the more common lines in galaxies ([O ii] λ 3727, [Ne iii] λ 3869, H β , [O iii] λλ 4959, 5007, H α , and [N ii] λλ 6548, 6584). These data provide an optical classification for 151 (i.e., 33%) of the C-COSMOS narrow-line galaxies based on emission-line diagnostic diagrams.

The Chandra Source Catalog: Spectral Properties

Science.gov (United States)

Doe, Stephen; Siemiginowska, Aneta L.; Refsdal, Brian L.; Evans, Ian N.; Anderson, Craig S.; Bonaventura, Nina R.; Chen, Judy C.; Davis, John E.; Evans, Janet D.; Fabbiano, Giuseppina; Galle, Elizabeth C.; Gibbs, Danny G., II; Glotfelty, Kenny J.; Grier, John D.; Hain, Roger; Hall, Diane M.; Harbo, Peter N.; He, Xiang Qun (Helen); Houck, John C.; Karovska, Margarita; Kashyap, Vinay L.; Lauer, Jennifer; McCollough, Michael L.; McDowell, Jonathan C.; Miller, Joseph B.; Mitschang, Arik W.; Morgan, Douglas L.; Mossman, Amy E.; Nichols, Joy S.; Nowak, Michael A.; Plummer, David A.; Primini, Francis A.; Rots, Arnold H.; Sundheim, Beth A.; Tibbetts, Michael S.; van Stone, David W.; Winkelman, Sherry L.; Zografou, Panagoula

2009-09-01

The first release of the Chandra Source Catalog (CSC) contains all sources identified from eight years' worth of publicly accessible observations. The vast majority of these sources have been observed with the ACIS detector and have spectral information in 0.5-7 keV energy range. Here we describe the methods used to automatically derive spectral properties for each source detected by the standard processing pipeline and included in the final CSC. Hardness ratios were calculated for each source between pairs of energy bands (soft, medium and hard) using the Bayesian algorithm (BEHR, Park et al. 2006). The sources with high signal to noise ratio (exceeding 150 net counts) were fit in Sherpa (the modeling and fitting application from the Chandra Interactive Analysis of Observations package, developed by the Chandra X-ray Center; see Freeman et al. 2001). Two models were fit to each source: an absorbed power law and a blackbody emission. The fitted parameter values for the power-law and blackbody models were included in the catalog with the calculated flux for each model. The CSC also provides the source energy flux computed from the normalizations of predefined power-law and black-body models needed to match the observed net X-ray counts. In addition, we provide access to data products for each source: a file with source spectrum, the background spectrum, and the spectral response of the detector. This work is supported by NASA contract NAS8-03060 (CXC).

Patel, Prof. Chandra Kumar Naranbhai

Indian Academy of Sciences (India)

Patel, Prof. Chandra Kumar Naranbhai. Date of birth: 2 July 1938. Address: President & CEO, Pranalytica Inc., 1101, Colorado Avenue, Santa Monica, CA 90401, U.S.A.. Contact: Office: (+1-310) 458 0808. Residence: (+1-310) 471 6505. Fax: (+1-310) 458 0171. Email: patel@pranalytica.com. YouTube · Twitter · Facebook ...

Chandra Source Catalog: User Interface

Science.gov (United States)

Bonaventura, Nina; Evans, Ian N.; Rots, Arnold H.; Tibbetts, Michael S.; van Stone, David W.; Zografou, Panagoula; Primini, Francis A.; Glotfelty, Kenny J.; Anderson, Craig S.; Chen, Judy C.; Davis, John E.; Doe, Stephen M.; Evans, Janet D.; Fabbiano, Giuseppina; Galle, Elizabeth C.; Gibbs, Danny G., II; Grier, John D.; Hain, Roger; Hall, Diane M.; Harbo, Peter N.; He, Helen; Houck, John C.; Karovska, Margarita; Kashyap, Vinay L.; Lauer, Jennifer; McCollough, Michael L.; McDowell, Jonathan C.; Miller, Joseph B.; Mitschang, Arik W.; Morgan, Douglas L.; Mossman, Amy E.; Nichols, Joy S.; Nowak, Michael A.; Plummer, David A.; Refsdal, Brian L.; Siemiginowska, Aneta L.; Sundheim, Beth A.; Winkelman, Sherry L.

2009-09-01

The Chandra Source Catalog (CSC) is intended to be the definitive catalog of all X-ray sources detected by Chandra. For each source, the CSC provides positions and multi-band fluxes, as well as derived spatial, spectral, and temporal source properties. Full-field and source region data products are also available, including images, photon event lists, light curves, and spectra. The Chandra X-ray Center CSC website (http://cxc.harvard.edu/csc/) is the place to visit for high-level descriptions of each source property and data product included in the catalog, along with other useful information, such as step-by-step catalog tutorials, answers to FAQs, and a thorough summary of the catalog statistical characterization. Eight categories of detailed catalog documents may be accessed from the navigation bar on most of the 50+ CSC pages; these categories are: About the Catalog, Creating the Catalog, Using the Catalog, Catalog Columns, Column Descriptions, Documents, Conferences, and Useful Links. There are also prominent links to CSCview, the CSC data access GUI, and related help documentation, as well as a tutorial for using the new CSC/Google Earth interface. Catalog source properties are presented in seven scientific categories, within two table views: the Master Source and Source Observations tables. Each X-ray source has one ``master source'' entry and one or more ``source observation'' entries, the details of which are documented on the CSC ``Catalog Columns'' pages. The master source properties represent the best estimates of the properties of a source; these are extensively described on the following pages of the website: Position and Position Errors, Source Flags, Source Extent and Errors, Source Fluxes, Source Significance, Spectral Properties, and Source Variability. The eight tutorials (``threads'') available on the website serve as a collective guide for accessing, understanding, and manipulating the source properties and data products provided by the catalog.

Chandra Source Catalog: User Interfaces

Science.gov (United States)

Bonaventura, Nina; Evans, I. N.; Harbo, P. N.; Rots, A. H.; Tibbetts, M. S.; Van Stone, D. W.; Zografou, P.; Anderson, C. S.; Chen, J. C.; Davis, J. E.; Doe, S. M.; Evans, J. D.; Fabbiano, G.; Galle, E.; Gibbs, D. G.; Glotfelty, K. J.; Grier, J. D.; Hain, R.; Hall, D. M.; He, X.; Houck, J. C.; Karovska, M.; Lauer, J.; McCollough, M. L.; McDowell, J. C.; Miller, J. B.; Mitschang, A. W.; Morgan, D. L.; Nichols, J. S.; Nowak, M. A.; Plummer, D. A.; Primini, F. A.; Refsdal, B. L.; Siemiginowska, A. L.; Sundheim, B. A.; Winkelman, S. L.

2010-03-01

The CSCview data mining interface is available for browsing the Chandra Source Catalog (CSC) and downloading tables of quality-assured source properties and data products. Once the desired source properties and search criteria are entered into the CSCview query form, the resulting source matches are returned in a table along with the values of the requested source properties for each source. (The catalog can be searched on any source property, not just position.) At this point, the table of search results may be saved to a text file, and the available data products for each source may be downloaded. CSCview save files are output in RDB-like and VOTable format. The available CSC data products include event files, spectra, lightcurves, and images, all of which are processed with the CIAO software. CSC data may also be accessed non-interactively with Unix command-line tools such as cURL and Wget, using ADQL 2.0 query syntax. In fact, CSCview features a separate ADQL query form for those who wish to specify this type of query within the GUI. Several interfaces are available for learning if a source is included in the catalog (in addition to CSCview): 1) the CSC interface to Sky in Google Earth shows the footprint of each Chandra observation on the sky, along with the CSC footprint for comparison (CSC source properties are also accessible when a source within a Chandra field-of-view is clicked); 2) the CSC Limiting Sensitivity online tool indicates if a source at an input celestial location was too faint for detection; 3) an IVOA Simple Cone Search interface locates all CSC sources within a specified radius of an R.A. and Dec.; and 4) the CSC-SDSS cross-match service returns the list of sources common to the CSC and SDSS, either all such sources or a subset based on search criteria.

When Worlds Collide: Chandra Observes Titanic Merger

Science.gov (United States)

2002-04-01

NASA's Chandra X-ray Observatory has provided the best X-ray image yet of two Milky Way-like galaxies in the midst of a head-on collision. Since all galaxies - including our own - may have undergone mergers, this provides insight into how the universe came to look as it does today. Astronomers believe the mega-merger in the galaxy known as Arp 220 triggered the formation of huge numbers of new stars, sent shock waves rumbling through intergalactic space, and could possibly lead to the formation of a supermassive black hole in the center of the new conglomerate galaxy. The Chandra data also suggest that merger of these two galaxies began only 10 million years ago, a short time in astronomical terms. "The Chandra observations show that things really get messed up when two galaxies run into each other at full speed," said David Clements of the Imperial College, London, one of the team members involved in the study. "The event affects everything from the formation of massive black holes to the dispersal of heavy elements into the universe." Arp 220 is considered to be a prototype for understanding what conditions were like in the early universe, when massive galaxies and supermassive black holes were presumably formed by numerous galaxy collisions. At a relatively nearby distance of about 250 million light years, Arp 220 is the closest example of an "ultra-luminous" galaxy, one that gives off a trillion times as much radiation as our Sun. The Chandra image shows a bright central region at the waist of a glowing, hour-glass-shaped cloud of multimillion-degree gas. Rushing out of the galaxy at hundreds of thousands of miles per hour, the super-heated as forms a "superwind," thought to be due to explosive activity generated by the formation of hundreds of millions of new stars. Farther out, spanning a distance of 75,000 light years, are giant lobes of hot gas that could be galactic remnants flung into intergalactic space by the early impact of the collision. Whether the

Harish-Chandra Research Institute, Allahabad

Indian Academy of Sciences (India)

The Harish-Chandra Research Institute (known as the Mehta Research Institute of Math- ematics and Mathematical Physics until October 2000) came into existence in 1975, with a donation of some land and Rs. 40 lakhs from the B S Mehta Trust in Calcutta. With the aim of converting it into a top-class research Institute in ...

PROBING WOLF–RAYET WINDS: CHANDRA/HETG X-RAY SPECTRA OF WR 6

Energy Technology Data Exchange (ETDEWEB)

Huenemoerder, David P.; Schulz, N. S. [Massachusetts Institute of Technology, Kavli Institute for Astrophysics and Space Research, 70 Vassar St., Cambridge, MA 02139 (United States); Gayley, K. G. [Department of Physics and Astronomy, University of Iowa, Iowa City, IA 52242 (United States); Hamann, W.-R.; Oskinova, L.; Shenar, T. [Institut für Physik und Astronomie, Universität Potsdam, Karl-Liebknecht-Str. 24/25, D-14476 Potsdam (Germany); Ignace, R. [Department of Physics and Astronomy, East Tennessee State University, Johnson City, TN 37614 (United States); Nichols, J. S. [Harvard-Smithsonian Center for Astrophysics, 60 Garden St., MS 34, Cambridge, MA 02138 (United States); Pollock, A. M. T., E-mail: dph@space.mit.edu, E-mail: ken.gayley@gmail.com, E-mail: wrh@astro.physik.uni-potsdam.de, E-mail: lida@astro.physik.uni-potsdam.de, E-mail: shtomer@astro.physik.uni-potsdam.de, E-mail: ignace@mail.etsu.edu, E-mail: jnichols@cfa.harvard.edu [European Space Agency, ESAC, Apartado 78, E-28691 Villanueva de la Cañada (Spain)

2015-12-10

With a deep Chandra/HETGS exposure of WR 6, we have resolved emission lines whose profiles show that the X-rays originate from a uniformly expanding spherical wind of high X-ray-continuum optical depth. The presence of strong helium-like forbidden lines places the source of X-ray emission at tens to hundreds of stellar radii from the photosphere. Variability was present in X-rays and simultaneous optical photometry, but neither were correlated with the known period of the system or with each other. An enhanced abundance of sodium revealed nuclear-processed material, a quantity related to the evolutionary state of the star. The characterization of the extent and nature of the hot plasma in WR 6 will help to pave the way to a more fundamental theoretical understanding of the winds and evolution of massive stars.

Six Years Into Its Mission, NASA's Chandra X-ray Observatory Continues to Achieve Scientific Firsts

Science.gov (United States)

2005-08-01

In August 1999, NASA's Chandra X-ray Observatory opened for business. Six years later, it continues to achieve scientific firsts. "When Chandra opened its sunshade doors for the first time, it opened the possibility of studying the X-ray emission of the universe with unprecedented clarity," said Chandra project scientist Dr. Martin Weisskopf of NASA's Marshall Space Flight Center in Huntsville, Ala. "Already surpassing its goal of a five-year life, Chandra continues to rewrite textbooks with discoveries about our own solar system and images of celestial objects as far as billions of light years away." Based on the observatory's outstanding results, NASA Headquarters in Washington decided in 2001 to extend Chandra s mission from five years to ten. During the observatory s sixth year of operation, auroras from Jupiter, X-rays from Saturn, and the early days of our solar system were the focus of Chandra discoveries close to home -- discoveries with the potential to better understand the dynamics of life on Earth. Jupiter's auroras are the most spectacular and active auroras in the solar system. Extended Chandra observations revealed that Jupiter s auroral X-rays are caused by highly charged particles crashing into the atmosphere above Jupiter's poles. These results gave scientists information needed to compare Jupiter's auroras with those from Earth, and determine if they are triggered by different cosmic and planetary events. Mysterious X-rays from Saturn also received attention, as Chandra completed the first observation of a solar X-ray flare reflected from Saturn's low-latitudes, the region that correlates to Earth's equator and tropics. This observation led scientists to conclude the ringed planet may act as a mirror, reflecting explosive activity from the sun. Solar-storm watchers on Earth might see a surprising benefit. The results imply scientists could use giant planets like Saturn as remote-sensing tools to help monitor X-ray flaring on portions of the sun

Chandra Takes on Heavy Jets and Massive Winds in 4U 1630-47

Science.gov (United States)

Neilsen, Joey

2014-11-01

Recently, Díaz Trigo et al. reported the discovery of relativistic baryons in a jet in XMM/ATCA observations of the 2012 outburst of the black hole 4U 1630-47. We present a search for a similarly massive jet earlier in the same outburst using high-resolution X-ray spectra from the Chandra HETGS. Despite a detection of radio emission with ATCA, we find no evidence of a heavy jet in the X-ray spectrum, with tight upper limits on the relativistic emission lines seen by Díaz Trigo eight months later. Instead, we find deep absorption lines from a massive, highly ionized disk wind, whose properties can be probed with detailed photoionization models. We explore several scenarios to explain the two modes of massive outflow in this remarkable black hole system.

Coronal Physics and the Chandra Emission Line Project

Science.gov (United States)

Brickhouse, N. S.; Drake, J. J.

2000-01-01

With the launch of the Chandra X-ray Observatory, high resolution X-ray spectroscopy of cosmic sources has begun. Early, deep observations of three stellar coronal sources Capella, Procyon, and HR 1099 are providing not only invaluable calibration data, but also benchmarks for plasma spectral models. These models are needed to interpret data from stellar coronae, galaxies and clusters of galaxies, supernova, remnants and other astrophysical sources. They have been called into question in recent years as problems with understanding low resolution ASCA and moderate resolution Extreme Ultraviolet Explorer Satellite (EUVE) data have arisen. The Emission Line Project is a collaborative effort, to improve the models, with Phase I being the comparison of models with observed spectra of Capella, Procyon, and HR 1099. Goals of these comparisons are (1) to determine and verify accurate and robust diagnostics and (2) to identify and prioritize issues in fundamental spectroscopy which will require further theoretical and/or laboratory work. A critical issue in exploiting the coronal data for these purposes is to understand the extent, to which common simplifying assumptions (coronal equilibrium, negligible optical depth) apply. We will discuss recent, advances in our understanding of stellar coronae, in this context.

THE EVOLUTION OF THE FAR-UV LUMINOSITY FUNCTION AND STAR FORMATION RATE DENSITY OF THE CHANDRA DEEP FIELD SOUTH FROM z = 0.2 TO 1.2 WITH SWIFT/UVOT

Energy Technology Data Exchange (ETDEWEB)

Hagen, Lea M. Z.; Gronwall, Caryl; Wolf, Christopher; Siegel, Michael H.; Hagen, Alex [Department of Astronomy and Astrophysics, The Pennsylvania State University, University Park, PA 16802 (United States); Hoversten, Erik A. [Department of Physics and Astronomy, University of North Carolina at Chapel Hill, 120 E. Cameron Avenue, Chapel Hill, NC 27599 (United States); Page, Mathew, E-mail: lmz5057@psu.edu [Mullard Space Science Laboratory, University College London, Holmbury St Mary, Dorking, Surrey RH5 6NT (United Kingdom)

2015-08-01

We use deep Swift UV/Optical Telescope (UVOT) near-ultraviolet (1600–4000 Å) imaging of the Chandra Deep Field South to measure the rest-frame far-UV (FUV; 1500 Å) luminosity function (LF) in four redshift bins between z = 0.2 and 1.2. Our sample includes 730 galaxies with u < 24.1 mag. We use two methods to construct and fit the LFs: the traditional V{sub max} method with bootstrap errors, and a maximum likelihood estimator. We observe luminosity evolution such that M* fades by ∼2 mag from z ∼ 1 to z ∼ 0.3, implying that star formation activity was substantially higher at z ∼ 1 than today. We integrate our LFs to determine the FUV luminosity densities and star formation rate densities (SFRDs) from z = 0.2 to 1.2. We find evolution consistent with an increase proportional to (1 + z){sup 1.9} out to z ∼ 1. Our luminosity densities and star formation rates are consistent with those found in the literature but are, on average, a factor of ∼2 higher than previous FUV measurements. In addition, we combine our UVOT data with the MUSYC survey to model the galaxies’ ultraviolet-to-infrared spectral energy distributions and estimate the rest-frame FUV attenuation. We find that accounting for the attenuation increases the SFRDs by ∼1 dex across all four redshift bins.

Ten Years of Chandra

Science.gov (United States)

Weisskopf, Martin C.

2009-01-01

We celebrated the 10-th anniversary of the Launch of the Chandra X-ray Observatory on July 13, 2009. During these 10 years data from this Great Observatory have had a profound impact on 21st century astrophysics. With its unrivaled capability to produce sub-arcsecond images, the Observatory has enabled astronomers to make new discoveries in topics as diverse as comets and cosmology. We shall review some of the highlights, discuss the current status, and future plans.

Chandra Discovers X-ray Source at the Center of Our Galaxy

Science.gov (United States)

2000-01-01

Culminating 25 years of searching by astronomers, researchers at Massachusetts Institute of Technology say that a faint X-ray source, newly detected by NASA's Chandra X-ray Observatory, may be the long-sought X-ray emission from a known supermassive black hole at the center of our galaxy. Frederick K. Baganoff and colleagues from Pennsylvania State University, University Park, and the University of California, Los Angeles, will present their findings today in Atlanta at the 195th national meeting of the American Astronomical Society. Baganoff, lead scientist for the Chandra X-ray Observatory's Advanced CCD Imaging Spectrometer (ACIS) team's "Sagittarius A* and the Galactic Center" project and postdoctoral research associate at MIT, said that the precise positional coincidence between the new X-ray source and the radio position of a long-known source called Sagittarius A* "encourages us to believe that the two are the same." Sagittarius A* is a point-like, variable radio source at the center of our galaxy. It looks like a faint quasar and is believed to be powered by gaseous matter falling into a supermassive black hole with 2.6 million times the mass of our Sun. Chandra's remarkable detection of this X-ray source has placed astronomers within a couple of years of a coveted prize: measuring the spectrum of energy produced by Sagittarius A* to determine in detail how the supermassive black hole that powers it works. "The race to be the first to detect X-rays from Sagittarius A* is one of the hottest and longest-running in all of X-ray astronomy," Baganoff said. "Theorists are eager to hear the results of our observation so they can test their ideas." But now that an X-ray source close to Sagittarius A* has been found, it has taken researchers by surprise by being much fainter than expected. "There must be something unusual about the environment around this black hole that affects how it is fed and how the gravitational energy released from the infalling matter is

The Role of Project Science in the Chandra X-Ray Observatory

Science.gov (United States)

O'Dell, Stephen L.; Weisskopf, Martin C.

2006-01-01

The Chandra X-Ray Observatory, one of NASA's Great Observatories, has an outstanding record of scientific and technical success. This success results from the efforts of a team comprising NASA, its contractors, the Smithsonian Astrophysical Observatory, the instrument groups, and other elements of the scientific community, including thousands of scientists who utilize this powerful facility for astrophysical research. We discuss the role of NASA Project Science in the formulation, development, calibration, and operation of the Chandra X-ray Observatory. In addition to representing the scientific community within the Project, Project Science performed what we term "science systems engineering". This activity encompasses translation of science requirements into technical requirements and assessment of the scientific impact of programmatic and technical trades. We briefly describe several examples of science systems engineering conducted by Chandra Project Science.

Chandra Finds X-ray Star Bonanza in the Orion Nebula

Science.gov (United States)

2000-01-01

NASA's Chandra X-ray Observatory has resolved nearly a thousand faint X-ray-emitting stars in a single observation of young stars in the Orion Nebula. The discovery--the richest field of X-ray sources ever obtained in the history of X-ray astronomy--will be presented on Friday, January 14, at the 195th national meeting of the American Astronomical Society in Atlanta, Georgia. The Orion region is a dense congregation of about 2,000 very young stars formed during the past few million years. The discovery of such a wealth of X-ray stars in the closest massive star-forming region to Earth (only 1,500 light years away) is expected to have a profound impact on our understanding of star formation and evolution. "We've detected X-rays from so many fantastic objects, such as very young massive stars and stars so small that they may evolve into brown dwarfs," said Gordon Garmire, Evan Pugh Professor at Penn State University, University Park. "Chandra's superb angular resolution has resolved this dense cluster of stars with arcsecond accuracy and unsurpassed sensitivity." Garmire leads the team using Chandra's ACIS detector, the Advanced CCD Imaging Spectrometer, conceived and developed for NASA by Penn State University and the Massachusetts Institute of Technology. The brilliant Orion region has awed humankind for millennia. The most massive and brightest of these nascent stars are in the Orion Trapezium, which illuminates the Orion Nebula, also known as Messier 42. The Trapezium and its luminous gas can be seen with the unaided eye in the winter sky in the "sword" of the Orion constellation. Young stars, such as those found in Orion, are known to be much brighter in X-rays than middle-aged stars such as the Sun. The elevated X-ray emission is thought to arise from violent flares in strong magnetic fields near the surfaces of young stars. The Sun itself was probably thousands of times brighter in X-rays during its first few million years. Although the enhanced magnetic

Chandra Resolves Cosmic X-ray Glow and Finds Mysterious New Sources

Science.gov (United States)

2000-01-01

While taking a giant leap towards solving one of the greatest mysteries of X-ray astronomy, NASA's Chandra X-ray Observatory also may have revealed the most distant objects ever seen in the universe and discovered two puzzling new types of cosmic objects. Not bad for being on the job only five months. Chandra has resolved most of the X-ray background, a pervasive glow of X-rays throughout the universe, first discovered in the early days of space exploration. Before now, scientists have not been able to discern the background's origin, because no X-ray telescope until Chandra has had both the angular resolution and sensitivity to resolve it. "This is a major discovery," said Dr. Alan Bunner, Director of NASA's Structure andEvolution of the universe science theme. "Since it was first observed thirty-seven years ago, understanding the source of the X-ray background has been aHoly Grail of X-ray astronomy. Now, it is within reach." The results of the observation will be discussed today at the 195th national meeting of the American Astronomical Society in Atlanta, Georgia. An article describing this work has been submitted to the journal Nature by Dr. Richard Mushotzky, of NASA Goddard Space Flight Center, Greenbelt, Md., Drs. Lennox Cowie and Amy Barger at the University of Hawaii, Honolulu, and Dr. Keith Arnaud of the University of Maryland, College Park. "We are all very excited by this finding," said Mushotzky. "The resolution of most of the hard X-ray background during the first few months of the Chandra mission is a tribute to the power of this observatory and bodes extremely well for its scientific future," Scientists have known about the X-ray glow, called the X-ray background, since the dawn of X-ray astronomy in the early 1960s. They have been unable to discern its origin, however, for no X-ray telescope until Chandra has had both the angular resolution and sensitivity to resolve it. The German-led ROSAT mission, now completed, resolved much of the lower

Chandra Data Reveal Rapidly Whirling Black Holes

Science.gov (United States)

2008-01-01

A new study using results from NASA's Chandra X-ray Observatory provides one of the best pieces of evidence yet that many supermassive black holes are spinning extremely rapidly. The whirling of these giant black holes drives powerful jets that pump huge amounts of energy into their environment and affects galaxy growth. A team of scientists compared leading theories of jets produced by rotating supermassive black holes with Chandra data. A sampling of nine giant galaxies that exhibit large disturbances in their gaseous atmospheres showed that the central black holes in these galaxies must be spinning at near their maximum rates. People Who Read This Also Read... NASA’s Swift Satellite Catches First Supernova in The Act of Exploding Black Holes Have Simple Feeding Habits Jet Power and Black Hole Assortment Revealed in New Chandra Image Erratic Black Hole Regulates Itself "We think these monster black holes are spinning close to the limit set by Einstein's theory of relativity, which means that they can drag material around them at close to the speed of light," said Rodrigo Nemmen, a visiting graduate student at Penn State University, and lead author of a paper on the new results presented at American Astronomical Society in Austin, Texas. The research reinforces other, less direct methods previously used which have indicated that some stellar and supermassive black holes are spinning rapidly. According to Einstein's theory, a rapidly spinning black hole makes space itself rotate. This effect, coupled with gas spiraling toward the black hole, can produce a rotating, tightly wound vertical tower of magnetic field that flings a large fraction of the inflowing gas away from the vicinity of the black hole in an energetic, high-speed jet. Computer simulations by other authors have suggested that black holes may acquire their rapid spins when galaxies merge, and through the accretion of gas from their surroundings. "Extremely fast spin might be very common for large

Chandra X-ray Center Science Data Systems Regression Testing of CIAO

Science.gov (United States)

Lee, N. P.; Karovska, M.; Galle, E. C.; Bonaventura, N. R.

2011-07-01

The Chandra Interactive Analysis of Observations (CIAO) is a software system developed for the analysis of Chandra X-ray Observatory observations. An important component of a successful CIAO release is the repeated testing of the tools across various platforms to ensure consistent and scientifically valid results. We describe the procedures of the scientific regression testing of CIAO and the enhancements made to the testing system to increase the efficiency of run time and result validation.

The Chandra Source Catalog: X-ray Aperture Photometry

Science.gov (United States)

Kashyap, Vinay; Primini, F. A.; Glotfelty, K. J.; Anderson, C. S.; Bonaventura, N. R.; Chen, J. C.; Davis, J. E.; Doe, S. M.; Evans, I. N.; Evans, J. D.; Fabbiano, G.; Galle, E. C.; Gibbs, D. G., II; Grier, J. D.; Hain, R.; Hall, D. M.; Harbo, P. N.; He, X.; Houck, J. C.; Karovska, M.; Lauer, J.; McCollough, M. L.; McDowell, J. C.; Miller, J. B.; Mitschang, A. W.; Morgan, D. L.; Nichols, J. S.; Nowak, M. A.; Plummer, D. A.; Refsdal, B. L.; Rots, A. H.; Siemiginowska, A. L.; Sundheim, B. A.; Tibbetts, M. S.; van Stone, D. W.; Winkelman, S. L.; Zografou, P.

2009-09-01

The Chandra Source Catalog (CSC) represents a reanalysis of the entire ACIS and HRC imaging observations over the 9-year Chandra mission. We describe here the method by which fluxes are measured for detected sources. Source detection is carried out on a uniform basis, using the CIAO tool wavdetect. Source fluxes are estimated post-facto using a Bayesian method that accounts for background, spatial resolution effects, and contamination from nearby sources. We use gamma-function prior distributions, which could be either non-informative, or in case there exist previous observations of the same source, strongly informative. The current implementation is however limited to non-informative priors. The resulting posterior probability density functions allow us to report the flux and a robust credible range on it.

Invited Review Article: The Chandra X-ray Observatory

Science.gov (United States)

Schwartz, Daniel A.

2014-06-01

The Chandra X-ray Observatory is an orbiting x-ray telescope facility. It is one of the National Aeronautics and Space Administration's four "Great Observatories" that collectively have carried out astronomical observations covering the infrared through gamma-ray portion of the electromagnetic spectrum. Chandra is used by astronomers world-wide to acquire imaging and spectroscopic data over a nominal 0.1-10 keV (124-1.24 Å) range. We describe the three major parts of the observatory: the telescope, the spacecraft systems, and the science instruments. This article will emphasize features of the design and development driven by some of the experimental considerations unique to x-ray astronomy. We will update the on-orbit performance and present examples of the scientific highlights.

The Chandra Source Catalog 2.0: Interfaces

Science.gov (United States)

D'Abrusco, Raffaele; Zografou, Panagoula; Tibbetts, Michael; Allen, Christopher E.; Anderson, Craig S.; Budynkiewicz, Jamie A.; Burke, Douglas; Chen, Judy C.; Civano, Francesca Maria; Doe, Stephen M.; Evans, Ian N.; Evans, Janet D.; Fabbiano, Giuseppina; Gibbs, Danny G., II; Glotfelty, Kenny J.; Graessle, Dale E.; Grier, John D.; Hain, Roger; Hall, Diane M.; Harbo, Peter N.; Houck, John C.; Lauer, Jennifer L.; Laurino, Omar; Lee, Nicholas P.; Martínez-Galarza, Rafael; McCollough, Michael L.; McDowell, Jonathan C.; Miller, Joseph; McLaughlin, Warren; Morgan, Douglas L.; Mossman, Amy E.; Nguyen, Dan T.; Nichols, Joy S.; Nowak, Michael A.; Paxson, Charles; Plummer, David A.; Primini, Francis Anthony; Rots, Arnold H.; Siemiginowska, Aneta; Sundheim, Beth A.; Van Stone, David W.

2018-01-01

Easy-to-use, powerful public interfaces to access the wealth of information contained in any modern, complex astronomical catalog are fundamental to encourage its usage. In this poster,I present the public interfaces of the second Chandra Source Catalog (CSC2). CSC2 is the most comprehensive catalog of X-ray sources detected by Chandra, thanks to the inclusion of Chandra observations public through the end of 2014 and to methodological advancements. CSC2 provides measured properties for a large number of sources that sample the X-ray sky at fainter levels than the previous versions of the CSC, thanks to the stacking of single overlapping observations within 1’ before source detection. Sources from stacks are then crossmatched, if multiple stacks cover the same area of the sky, to create a list of unique, optimal CSC2 sources. The properties of sources detected in each single stack and each single observation are also measured. The layered structure of the CSC2 catalog is mirrored in the organization of the CSC2 database, consisting of three tables containing all properties for the unique stacked sources (“Master Source”), single stack sources (“Stack Source”) and sources in any single observation (“Observation Source”). These tables contain estimates of the position, flags, extent, significances, fluxes, spectral properties and variability (and associated errors) for all classes of sources. The CSC2 also includes source region and full-field data products for all master sources, stack sources and observation sources: images, photon event lists, light curves and spectra.CSCview, the main interface to the CSC2 source properties and data products, is a GUI tool that allows to build queries based on the values of all properties contained in CSC2 tables, query the catalog, inspect the returned table of source properties, browse and download the associated data products. I will also introduce the suite of command-line interfaces to CSC2 that can be used in

Deep Chandra Observations of ESO 428-G014. II. Spectral Properties and Morphology of the Large-scale Extended X-Ray Emission

Science.gov (United States)

Fabbiano, G.; Paggi, A.; Karovska, M.; Elvis, M.; Maksym, W. P.; Risaliti, G.; Wang, Junfeng

2018-03-01

We present a deep Chandra spectral and spatial study of the kpc-scale diffuse X-ray emission of the Compton-thick (CT) active galactic nucleus (AGN) ESO 428-G014. The entire spectrum is best fit with composite photoionization + thermal models. The diffuse emission is more extended at lower energies (<3 keV). The smaller extent of the hard continuum and Fe Kα profiles implies that the optically thicker clouds responsible for this scattering may be relatively more prevalent closer to the nucleus. These clouds must not prevent soft ionizing X-rays from the AGN escaping to larger radii, in order to have photoionized ISM at larger radii. This suggests that at smaller radii, there may be a larger population of molecular clouds to scatter the hard X-rays, as in the Milky Way. The diffuse emission is also significantly extended in the cross-cone direction, where the AGN emission would be mostly obscured by the torus in the standard AGN model. Our results suggest that the transmission of the obscuring region in the cross-cone direction is ∼10% of that in the cone direction. In the 0.3–1.5 keV band, the ratio of cross-cone to cone photons increases to ∼84%, suggesting an additional soft diffuse emission component disjoint from the AGN. This could be due to hot ISM trapped in the potential of the galaxy. The luminosity of this component, ∼5 × 1038 erg s‑1, is roughly consistent with the thermal component suggested by the spectral fits in the 170–900 pc annulus.

THE SUB-mJy RADIO POPULATION OF THE E-CDFS: OPTICAL AND INFRARED COUNTERPART IDENTIFICATION

Energy Technology Data Exchange (ETDEWEB)

Bonzini, M.; Mainieri, V.; Padovani, P.; Rosati, P. [ESO, Karl-Schwarzschild-Strasse 2, D-85748 Garching (Germany); Kellermann, K. I. [National Radio Astronomy Observatory, 520 Edgemont Road, Charlottesville, VA 22903-2475 (United States); Miller, N. [Department of Astronomy, University of Maryland, College Park, MD 20742-2421 (United States); Tozzi, P.; Balestra, I. [INAF Osservatorio Astronomico di Trieste, via G.B. Tiepolo 11, I-34131, Trieste (Italy); Vattakunnel, S. [Dipartimento di Fisica Universit di Trieste, piazzale Europa 1, I-34127 Trieste (Italy); Brandt, W. N.; Luo, B. [Department of Astronomy and Astrophysics, Pennsylvania State University, University Park, PA 16802 (United States); Xue, Y. Q., E-mail: mbonzini@eso.org [Key Laboratory for Research in Galaxies and Cosmology, Department of Astronomy, University of Science and Technology of China, Chinese Academy of Sciences, Hefei, Anhui 230026 (China)

2012-11-15

We study a sample of 883 sources detected in a deep Very Large Array survey at 1.4 GHz in the Extended Chandra Deep Field South. This paper focuses on the identification of their optical and infrared (IR) counterparts. We use a likelihood-ratio technique that is particularly useful when dealing with deep optical images to minimize the number of spurious associations. We find a reliable counterpart for 95% of our radio sources. Most of the counterparts (74%) are detected at optical wavelengths, but there is a significant fraction (21%) that are only detectable in the IR. Combining newly acquired optical spectra with data from the literature, we are able to assign a redshift to 81% of the identified radio sources (37% spectroscopic). We also investigate the X-ray properties of the radio sources using the Chandra 4 Ms and 250 ks observations. In particular, we use a stacking technique to derive the average properties of radio objects undetected in the Chandra images. The results of our analysis are collected in a new catalog containing the position of the optical/IR counterpart, the redshift information, and the X-ray fluxes. It is the deepest multi-wavelength catalog of radio sources, which will be used for future study of this galaxy population.

Acharya Prafulla Chandra at the College of Science

Indian Academy of Sciences (India)

and by his remarkable book, 'History of Hindu Chemistry'. His activities progressed ... chemistry journals in England, Germany and America. Prafulla. Chandra ... Presidency College in 1889, he wrote an illustrated zoology primer for children.

Chandra Finds Surprising Black Hole Activity In Galaxy Cluster

Science.gov (United States)

2002-09-01

harsh treatment galaxies suffer in clusters, and are now coming out of retirement," said Martini. This could imply that galaxies are better at holding onto a supply of gas and dust than previously thought, particularly deep down at their cores near the supermassive black hole. This gas and dust may also be the same material that obscures the AGN at other wavelengths. The presence of so many AGN could also contribute to the radio and infrared radiation from the clusters, which until now was thought to be almost exclusively a product of star formation. Thus, scientists may be overestimating the amount of star formation taking place in clusters. The Carnegie group has begun a study of other galaxy clusters with Chandra. Martini and Kelson are postdoctoral researchers at the Carnegie Observatories in Pasadena; Mulchaey is a staff astronomer. NASA's Marshall Space Flight Center in Huntsville, Ala., manages the Chandra program, and TRW, Inc., Redondo Beach, Calif., is the prime contractor. The Smithsonian's Chandra X-ray Center controls science and flight operations from Cambridge, Mass.

NASA Chandra X-ray Observatory Selected as Editor's Choice in 2000 Discover Magazine Awards for Technological Innovation

Science.gov (United States)

2000-06-01

The Chandra X-ray Observatory, NASA's newest and most powerful X-ray space telescope, has been selected as the winner of the Editor's Choice category of the 2000 Discover Magazine Awards for Technological Innovation. The team of government, industry, university and research institutions that designed, built and deployed Chandra for NASA's Marshall Space Flight Center, Huntsville, Ala, will be formally recognized June 24 at a gala awards celebration at Epcot at the Walt Disney World Resort in Orlando, Fl. Dr. Harvey Tananbaum, director of the Smithsonian Astrophysical Observatory's Chandra X-ray Science Center, Cambridge, Mass., which conducts the Chandra science mission for NASA, will receive the award on behalf of the team. "Chandra has opened a new window for astronomers into the universe of high-energy cosmic events such as pulsars, supernova remnants and black holes," said Tananbaum. "We're now able to create spectacularly detailed images of celestial phenomena whose mere existence we could only hypothesize before." Among Chandra's most significant discoveries to date, he lists the detection of a giant ring around the heart of the Crab Nebula, details of the shock wave created by an exploding star and resolution of the high-energy X-ray "glow" in the universe into millions of specific light sources. "The successful launch, deployment and on-orbit operations of NASA's Chandra X-ray Observatory is a testament to the solid partnership between TRW, NASA and the science community that has been enabling NASA's most important space science missions for the past 40 years," said Timothy W. Hannemann, executive vice president and general manager, TRW Space & Electronics Group. "The extraordinary images that Chandra is delivering daily speaks loudly not only to the quality of the science instruments on board, but also to the engineering talents and dedication to mission success exhibited by every member of NASA's Chandra mission team." Chandra, named in honor of Nobel

Chandra Grating Spectroscopy of Three Hot White Dwarfs

Science.gov (United States)

Adamczak, J.; Werner, K.; Rauch, T.; Schuh, S.; Drake, J. J.; Kruk, J. W.

2013-01-01

High-resolution soft X-ray spectroscopic observations of single hot white dwarfs are scarce. With the Chandra Low-Energy Transmission Grating, we have observed two white dwarfs, one is of spectral type DA (LB1919) and the other is a non-DA of spectral type PG1159 (PG1520+525). The spectra of both stars are analyzed, together with an archival Chandra spectrum of another DA white dwarf (GD246). Aims. The soft X-ray spectra of the two DA white dwarfs are investigated in order to study the effect of gravitational settling and radiative levitation of metals in their photospheres. LB1919 is of interest because it has a significantly lower metallicity than DAs with otherwise similar atmospheric parameters. GD246 is the only white dwarf known that shows identifiable individual iron lines in the soft X-ray range. For the PG1159 star, a precise effective temperature determination is performed in order to confine the position of the blue edge of the GW Vir instability region in the HRD. Methods. The Chandra spectra are analyzed with chemically homogeneous as well as stratified NLTE model atmospheres that assume equilibrium between gravitational settling and radiative acceleration of chemical elements. Archival EUV and UV spectra obtained with EUVE, FUSE, and HST are utilized to support the analysis. Results. No metals could be identified in LB1919. All observations are compatible with a pure hydrogen atmosphere. This is in stark contrast to the vast majority of hot DA white dwarfs that exhibit light and heavy metals and to the stratified models that predict significant metal abundances in the atmosphere. For GD246 we find that neither stratified nor homogeneous models can fit the Chandra spectrum. The Chandra spectrum of PG1520+525 constrains the effective temperature to T(sub eff) = 150 000 +/- 10 000 K. Therefore, this nonpulsating star together with the pulsating prototype of the GWVir class (PG1159-035) defines the location of the blue edge of the GWVir instability region

NASA's Chandra Reveals Origin of Key Cosmic Explosions

Science.gov (United States)

2010-02-01

WASHINGTON -- New findings from NASA's Chandra X-ray Observatory have provided a major advance in understanding a type of supernova critical for studying the dark energy that astronomers think pervades the universe. The results show mergers of two dense stellar remnants are the likely cause of many of the supernovae that have been used to measure the accelerated expansion of the universe. These supernovae, called Type Ia, serve as cosmic mile markers to measure expansion of the universe because they can be seen at large distances, and they follow a reliable pattern of brightness. However, until now, scientists have been unsure what actually causes the explosions. "These are such critical objects in understanding the universe," said Marat Gilfanov of the Max Planck Institute for Astrophysics in Germany and lead author of the study that appears in the Feb. 18 edition of the journal Nature. "It was a major embarrassment that we did not know how they worked. Now we are beginning to understand what lights the fuse of these explosions." Most scientists agree a Type Ia supernova occurs when a white dwarf star -- a collapsed remnant of an elderly star -- exceeds its weight limit, becomes unstable and explodes. Scientists have identified two main possibilities for pushing the white dwarf over the edge: two white dwarfs merging or accretion, a process in which the white dwarf pulls material from a sun-like companion star until it exceeds its weight limit. "Our results suggest the supernovae in the galaxies we studied almost all come from two white dwarfs merging," said co-author Akos Bogdan, also of Max Planck. "This is probably not what many astronomers would expect." The difference between these two scenarios may have implications for how these supernovae can be used as "standard candles" -- objects of a known brightness -- to track vast cosmic distances. Because white dwarfs can come in a range of masses, the merger of two could result in explosions that vary somewhat in

Chandra Looks Over a Cosmic Four-Leaf Clover

Science.gov (United States)

2004-07-01

A careful analysis of observations by NASA's Chandra X-ray Observatory of a rare quadruple quasar has uncovered evidence that possibly a single star in a foreground galaxy magnified X-rays coming from the quasar. This discovery gives astronomers a new and extremely precise probe of the gas flow around the supermassive black hole that powers the quasar. "If our interpretation is correct, then we are seeing details around this black hole that are 50,000 times smaller than either the Hubble Space Telescope or Chandra could see under ordinary circumstances," said George Chartas of Penn State University in University Park, and lead author of a recent article on the Cloverleaf quasar in The Astrophysical Journal. The Cloverleaf quasar is a single object about 11 billion light years from Earth that appears as four images produced by a process known as gravitational lensing. If one or more galaxies lie along the line of sight to a more distant quasar, the gravitational field of the intervening galaxies can bend and magnify the light from the quasar and produce multiple images of it. The four images of the Cloverleaf quasar have been produced by one or more intervening galaxies. Cloverleaf Quasar Chandra X-ray Image of the Cloverleaf quasar One of the images (A), in the Cloverleaf is brighter than the others in both optical and X-ray light. Chartas and his colleagues found the relative brightness of this image was greater in X-ray than in optical light. The X-rays from iron atoms were also enhanced relative to X-rays at lower energies. Since the amount of brightening due to gravitational lensing does not vary with the wavelength, this means that an additional object has magnified the X-rays. The increased magnification of the X-ray light can be explained by gravitational microlensing, an effect which has been used to search for compact stars and planets in our galaxy. Microlensing occurs when a star or a multiple star system passes in front of light from a background object

APC implementation in Chandra Asri - ethylene plant

Science.gov (United States)

Sidiq, Mochamad; Mustofa, Ali

2017-05-01

Nowadays, the modern process plants are continuously improved for maximizing production, Optimization of the energy and raw material and reducing the risk. Due to many disturbances appearance between the process units, hence, the failure of one unit might have a bad effect on the overall productivity. Ethylene Plant have significant opportunities for using Advanced Process Control (APC) technologies to improve operation stability, push closer to quality or equipment limit, and improve the capability of process units to handle disturbances. APC implementation had considered a best answer for solving multivariable control problem. PT. Chandra Asri Petrochemical, Tbk (CAP) operates a large naphtha cracker complex at Cilegon, Indonesia. To optimize the plant operation and to enhance the benefit, Chandra Asri has been decided to implement Advance Process Control (APC) for ethylene plant. The APC implementation technology scopes at CAP are as follows: 1. Hot Section : Furnaces, Quench Tower 2. Cold Section : Demethanizer, Deethanizer, Acetylene Converter, Ethylene Fractionator, Depropanizer, Propylene Fractionator, Debutanizer

AN ALMA SURVEY OF SUBMILLIMETER GALAXIES IN THE EXTENDED CHANDRA DEEP FIELD SOUTH: NEAR-INFRARED MORPHOLOGIES AND STELLAR SIZES

Energy Technology Data Exchange (ETDEWEB)

Chen, Chian-Chou; Smail, Ian; Swinbank, A. M.; Simpson, J. M.; Ma, Cheng-Jiun; Alexander, D. M.; Danielson, A. L. R.; Edge, A. C. [Institute for Computational Cosmology, Durham University, South Road, Durham DH1 3LE (United Kingdom); Biggs, A. D.; Ivison, R. J. [European Southern Observatory, Karl Schwarzschild Strasse 2, D-85748 Garching (Germany); Brandt, W. N. [Department of Astronomy and Astrophysics, 525 Davey Lab, Pennsylvania State University, University Park, PA 16802 (United States); Chapman, S. C. [Department of Physics and Atmospheric Science, Dalhousie University, Halifax, NS B3H 3J5 (Canada); Coppin, K. E. K. [Centre for Astrophysics Research, Science and Technology Research Institute, University of Hertfordshire, Hatfield AL10 9AB (United Kingdom); Dannerbauer, H. [Institut für Astrophysik, Universität Wien, Türkenschanzstraße 17, A-1180 Wien (Austria); Greve, T. R. [Department of Physics and Astronomy, University College London, Gower Street, London WC1E 6BT (United Kingdom); Karim, A. [Argelander-Institute for Astronomy, Bonn University, Auf dem Hügel 71, D-53121 Bonn (Germany); Menten, Karl M. [Max-Planck-Institut für Radioastronomie, Auf dem Hügel 69, D-53121 Bonn (Germany); Schinnerer, E.; Walter, F. [Max-Planck Institute for Astronomy, Königstuhl 17, D-69117 Heidelberg (Germany); Wardlow, J. L. [Dark Cosmology Centre, Niels Bohr Institute, University of Copenhagen, DK-2100 Copenhagen (Denmark); and others

2015-02-01

We analyze Hubble Space Telescope WFC3/H {sub 160}-band observations of a sample of 48 Atacama Large Millimeter/submillimeter Array detected submillimeter galaxies (SMGs) in the Extended Chandra Deep Field South field, to study their stellar morphologies and sizes. We detect 79% ± 17% of the SMGs in the H {sub 160}-band imaging with a median sensitivity of 27.8 mag, and most (80%) of the nondetections are SMGs with 870 μm fluxes of S {sub 870} < 3 mJy. With a surface brightness limit of μ {sub H} ∼ 26 mag arcsec{sup –2}, we find that 82% ± 9% of the H {sub 160}-band-detected SMGs at z = 1-3 appear to have disturbed morphologies, meaning they are visually classified as either irregulars or interacting systems, or both. By determining a Sérsic fit to the H {sub 160} surface brightness profiles, we derive a median Sérsic index of n = 1.2 ± 0.3 and a median half-light radius of r{sub e} = 4.4{sub −0.5}{sup +1.1} kpc for our SMGs at z = 1-3. We also find significant displacements between the positions of the H {sub 160} component and 870 μm emission in these systems, suggesting that the dusty starburst regions and less-obscured stellar distribution are not colocated. We find significant differences in the sizes and the Sérsic index between our z = 2-3 SMGs and z ∼ 2 quiescent galaxies, suggesting that a major transformation of the stellar light profile is needed in the quenching processes if SMGs are progenitors of the red-and-dead z ∼ 2 galaxies. Given the short-lived nature of SMGs, we postulate that the majority of the z = 2-3 SMGs with S {sub 870} ≳ 2 mJy are early/mid-stage major mergers.

Chandra Sees Wealth Of Black Holes In Star-Forming Galaxies

Science.gov (United States)

2001-06-01

NASA's Chandra X-ray Observatory has found new populations of suspected mid-mass black holes in several starburst galaxies, where stars form and explode at an unusually high rate. Although a few of these objects had been found previously, this is the first time they have been detected in such large numbers and could help explain their relationship to star formation and the production of even more massive black holes. At the 198th meeting of the American Astronomical Society in Pasadena, California, three independent teams of scientists reported finding dozens of X-ray sources in galaxies aglow with star formation. These X-ray objects appear point-like and are ten to a thousand times more luminous in X-rays than similar sources found in our Milky Way and the M81 galaxy. "Chandra gives us the ability to study the populations of individual bright X-ray sources in nearby galaxies in extraordinary detail," said Andreas Zezas, lead author from the Harvard-Smithsonian Center for Astrophysics team that observed The Antennae, a pair of colliding galaxies, and M82, a well-known starburst galaxy. "This allows us to build on earlier detections of these objects and better understand their relationship to starburst galaxies." Antennae-True Color Image True Color Image of Antennae Credit: NASA/SAO/G.Fabbiano et al. Press Image and Caption Kimberly Weaver, of NASA's Goddard Space Flight Center in Greenbelt, MD, lead scientist of the team that studied the starburst galaxy NGC 253, discussed the importance of the unusual concentration of these very luminous X-ray sources near the center of that galaxy. Four sources, which are tens to thousands of times more massive than the Sun, are located within 3,000 light years of the galaxy core. "This may imply that these black holes are gravitating toward the center of the galaxy where they could coalesce to form a single supermassive black hole," Weaver suggested. "It could be that this starburst galaxy is transforming itself into a quasar

The Chandra X-ray Observatory data processing system

Science.gov (United States)

Evans, Ian; Cresitello-Dittmar, Mark; Doe, Stephen; Evans, Janet; Fabbiano, Giuseppina; Germain, Gregg; Glotfelty, Kenny; Plummer, David; Zografou, Panagoula

2006-06-01

Raw data from the Chandra X-ray Observatory are processed by a set of standard data processing pipelines to create scientifically useful data products appropriate for further analysis by end users. Fully automated pipelines read the dumped raw telemetry byte stream from the spacecraft and perform the common reductions and calibrations necessary to remove spacecraft and instrumental signatures and convert the data into physically meaningful quantities that can be further analyzed by observers. The resulting data products are subject to automated validation to ensure correct pipeline processing and verify that the spacecraft configuration and scheduling matched the observers request and any constraints. In addition, pipeline processing monitors science and engineering data for anomalous indications and trending, and triggers alerts if appropriate. Data products are ingested and stored in the Chandra Data Archive, where they are made available for downloading by users. In this paper, we describe the architecture of the data processing system, including the scientific algorithms that are applied to the data, and interfaces to other subsystems. We place particular emphasis on the impacts of design choices on system integrity and maintainability. We review areas where algorithmic improvements or changes in instrument characteristics have required significant enhancements, and the mechanisms used to effect these changes while assuring continued scientific integrity and robustness. We discuss major enhancements to the data processing system that are currently being developed to automate production of the Chandra Source Catalog.

THE X-RAY FLUX DISTRIBUTION OF SAGITTARIUS A* AS SEEN BY CHANDRA

International Nuclear Information System (INIS)

Neilsen, J.; Anton Pannekoek, University of Amsterdam, Postbus 94249, 1090 GE Amsterdam (Netherlands))" data-affiliation=" (Astronomical Institute, Anton Pannekoek, University of Amsterdam, Postbus 94249, 1090 GE Amsterdam (Netherlands))" >Markoff, S.; Nowak, M. A.; Baganoff, F. K.; Dexter, J.; Witzel, G.; Barrière, N.; Li, Y.; Degenaar, N.; Fragile, P. C.; Gammie, C.; Goldwurm, A.; Grosso, N.; Haggard, D.

2015-01-01

We present a statistical analysis of the X-ray flux distribution of Sgr A* from the Chandra X-Ray Observatory's 3 Ms Sgr A* X-ray Visionary Project in 2012. Our analysis indicates that the observed X-ray flux distribution can be decomposed into a steady quiescent component, represented by a Poisson process with rate Q = (5.24 ± 0.08) × 10 –3  counts s –1 , and a variable component, represented by a power law process (dN/dF∝F –ξ , ξ=1.92 −0.02 +0.03 ). This slope matches our recently reported distribution of flare luminosities. The variability may also be described by a log-normal process with a median unabsorbed 2-8 keV flux of 1.8 −0.6 +0.8 ×10 −14  erg s –1  cm –2 and a shape parameter σ = 2.4 ± 0.2, but the power law provides a superior description of the data. In this decomposition of the flux distribution, all of the intrinsic X-ray variability of Sgr A* (spanning at least three orders of magnitude in flux) can be attributed to flaring activity, likely in the inner accretion flow. We confirm that at the faint end, the variable component contributes ∼10% of the apparent quiescent flux, as previously indicated by our statistical analysis of X-ray flares in these Chandra observations. Our flux distribution provides a new and important observational constraint on theoretical models of Sgr A*, and we use simple radiation models to explore the extent to which a statistical comparison of the X-ray and infrared can provide insights into the physics of the X-ray emission mechanism

THE X-RAY FLUX DISTRIBUTION OF SAGITTARIUS A* AS SEEN BY CHANDRA

Energy Technology Data Exchange (ETDEWEB)

Neilsen, J. [Department of Astronomy, Boston University, Boston, MA 02215 (United States); Markoff, S. [Astronomical Institute, " Anton Pannekoek," University of Amsterdam, Postbus 94249, 1090 GE Amsterdam (Netherlands); Nowak, M. A.; Baganoff, F. K. [MIT Kavli Institute for Astrophysics and Space Research, Cambridge, MA 02139 (United States); Dexter, J. [Department of Astronomy, Hearst Field Annex, University of California, Berkeley, CA 94720-3411 (United States); Witzel, G. [Department of Physics and Astronomy, University of California, Los Angeles, CA 90095-1547 (United States); Barrière, N. [Space Sciences Laboratory, 7 Gauss Way, University of California, Berkeley, CA 94720-7450 (United States); Li, Y. [Department of Astronomy and Institute of Theoretical Physics and Astrophysics, Xiamen University, Xiamen, Fujian 361005 (China); Degenaar, N. [Institute of Astronomy, University of Cambridge, Cambridge, CB3 OHA (United Kingdom); Fragile, P. C. [Department of Physics and Astronomy, College of Charleston, Charleston, SC 29424 (United States); Gammie, C. [Department of Astronomy, University of Illinois Urbana-Champaign, 1002 West Green Street, Urbana, IL 61801 (United States); Goldwurm, A. [AstroParticule et Cosmologie (APC), Université Paris 7 Denis Diderot, F-75205 Paris cedex 13 (France); Grosso, N. [Observatoire Astronomique de Strasbourg, Université de Strasbourg, CNRS, UMR 7550, 11 rue de l' Université, F-67000 Strasbourg (France); Haggard, D., E-mail: jneilsen@space.mit.edu [Department of Physics and Astronomy, AC# 2244, Amherst College, Amherst, MA 01002 (United States)

2015-02-01

We present a statistical analysis of the X-ray flux distribution of Sgr A* from the Chandra X-Ray Observatory's 3 Ms Sgr A* X-ray Visionary Project in 2012. Our analysis indicates that the observed X-ray flux distribution can be decomposed into a steady quiescent component, represented by a Poisson process with rate Q = (5.24 ± 0.08) × 10{sup –3} counts s{sup –1}, and a variable component, represented by a power law process (dN/dF∝F {sup –ξ}, ξ=1.92{sub −0.02}{sup +0.03}). This slope matches our recently reported distribution of flare luminosities. The variability may also be described by a log-normal process with a median unabsorbed 2-8 keV flux of 1.8{sub −0.6}{sup +0.8}×10{sup −14} erg s{sup –1} cm{sup –2} and a shape parameter σ = 2.4 ± 0.2, but the power law provides a superior description of the data. In this decomposition of the flux distribution, all of the intrinsic X-ray variability of Sgr A* (spanning at least three orders of magnitude in flux) can be attributed to flaring activity, likely in the inner accretion flow. We confirm that at the faint end, the variable component contributes ∼10% of the apparent quiescent flux, as previously indicated by our statistical analysis of X-ray flares in these Chandra observations. Our flux distribution provides a new and important observational constraint on theoretical models of Sgr A*, and we use simple radiation models to explore the extent to which a statistical comparison of the X-ray and infrared can provide insights into the physics of the X-ray emission mechanism.

TGCat, The Chandra Transmission Grating Catalog and Archive: Systems, Design and Accessibility

OpenAIRE

Mitschang, Arik W.; Huenemoerder, David P.; Nichols, Joy S.

2009-01-01

The recently released Chandra Transmission Grating Catalog and Archive, TGCat, presents a fully dynamic on-line catalog allowing users to browse and categorize Chandra gratings observations quickly and easily, generate custom plots of resulting response corrected spectra on-line without the need for special software and to download analysis ready products from multiple observations in one convenient operation. TGCat has been registered as a VO resource with the NVO providing direct access to ...

Chandra Finds Oxygen and Neon Ring in Ashes of Exploded Star

Science.gov (United States)

2000-01-01

NASA's Chandra X-ray Observatory has revealed an expanding ring-like structure of oxygen and neon that was hurled into space by the explosion of a massive star. The image of E0102-72 provides unprecedented details about the creation and dispersal of heavy elements necessary to form planets like Earth. The results were reported by Professor Claude Canizares of the Massachusetts Institute of Technology (MIT), Cambridge, at the 195th national meeting of the American Astronomical Society in Atlanta, Ga. Drs. Kathryn Flanagan, David Davis, and John Houck of MIT collaborated with Canizares in this investigation. E0102-72 is the remnant of a supernova explosion located in our neighbor galaxy, the Small Magellanic Cloud, nearly 200,000 light years away. It was created by the explosion of a star that was more than ten times as massive as our Sun. We are seeing the aftermath of the explosion a thousand or more years after the outburst. Shock waves are heating gas to temperatures of nearly 10 million degrees, so it glows with X-rays that are detected by Chandra's instruments. By using the High Energy Transmission Grating Spectrometer (HETG), astronomers were able to pinpoint the distribution of each chemical element individually and measure the velocities of different parts of the expanding ring. They also show the shock wave in a kind of "freeze-frame," revealing the progressive heating of the stellar matter as it plows into the surrounding gas. This is the first time such detailed X-ray information has ever been obtained for a supernova remnant, and should provide critical clues to the nature of supernovas. The grating spectrometer, which was built by an MIT team led by Canizares, spreads the X-rays according to their wavelength, giving distinct images of the object at specific wavelengths characteristic of each chemical element. Small wavelength shifts caused by the Doppler effect are used to measure the expansion velocities of each element independently. "We've been

A Chandra Study of Supernova Remnants in the Large and Small Magellanic Clouds

Science.gov (United States)

Schenck, Andrew Corey

2017-08-01

In the first part of this thesis we measure the interstellar abundances for the elements O, Ne, Mg, Si, and Fe in the Large Magellanic Cloud (LMC), based on the observational data of sixteen supernova remnants (SNRs) in the LMC as available in the public archive of the Chandra X-ray Observatory (Chandra). We find lower abundances than previous measurements based on a similar method using data obtained with the Advanced Satellite for Astrophysics and Cosmology (ASCA). We discuss the origins of the discrepancy between our Chandra and the previous ASCA measurements. We conclude that our measurements are generally more reliable than the ASCA results thanks to the high-resolution imaging spectroscopy with our Chandra data, although there remain some systematic uncertainties due to the use of different spectral modelings between the previous work and ours. We also discuss our results in comparison with the LMC abundance measurements based on optical observations of stars. The second part of this thesis is a detailed study of a core-collapse SNR B0049-73.6 in the Small Magellanic Cloud (SMC). Based on our deep Chandra observation, we detect metal-rich ejecta features extending out to the outermost boundary of B0049-73.6, which were not seen in the previous data. We find that the central nebula is dominated by emission from reverse-shocked ejecta material enriched in O, Ne, Mg, and Si. O-rich ejecta distribution is relatively smooth throughout the central nebula. In contrast the Si-rich material is highly structured. These results suggest that B0049-73.6 was produced by an asymmetric core-collapse explosion of a massive star. The estimated abundance ratios among these ejecta elements are in plausible agreement with the nucleosynthesis products from the explosion of a 13-15M. progenitor. We reveal that the central ring-like (in projection) ejecta nebula extends to ˜9 pc from the SNR center. This suggests that the contact discontinuity (CD) may be located at a further

An ALMA survey of submillimeter galaxies in the extended Chandra deep field south: The redshift distribution and evolution of submillimeter galaxies

Energy Technology Data Exchange (ETDEWEB)

Simpson, J. M.; Swinbank, A. M.; Smail, Ian; Alexander, D. M.; Danielson, A. L. R.; Thomson, A. P. [Institute for Computational Cosmology, Department of Physics, Durham University, South Road, Durham DH1 3LE (United Kingdom); Brandt, W. N. [Department of Astronomy and Astrophysics, 525 Davey Lab, Pennsylvania State University, University Park, PA 16802 (United States); Bertoldi, F.; Karim, A. [Argelander-Institute for Astronomy, Bonn University, Auf dem Hügel 71, D-53121 Bonn (Germany); De Breuck, C. [European Southern Observatory, Karl-Schwarzschild Straße, D-85748 Garching bei München (Germany); Chapman, S. C. [Department of Physics and Atmospheric Science, Dalhousie University, Halifax, NS B3H 3J5 (Canada); Coppin, K. E. K. [Centre for Astrophysics Research, Science and Technology Research Institute, University of Hertfordshire, Hatfield AL10 9AB (United Kingdom); Da Cunha, E.; Hodge, J. A.; Schinnerer, E. [Max-Planck Institute for Astronomy, Königstuhl 17, D-69117 Heidelberg (Germany); Dannerbauer, H. [Universität Wien, Institut für Astrophysik, Türkenschanzstraße 17, A-1180 Wien (Austria); Greve, T. R. [Department of Physics and Astronomy, University College London, Gower Street, London WC1E 6BT (United Kingdom); Ivison, R. J. [Institute for Astronomy, University of Edinburgh, Blackford Hill, Edinburgh EH9 3HJ (United Kingdom); Knudsen, K. K. [Department of Earth and Space Science, Onsala Space Observatory, Chalmers University of Technology, SE-43992 Onsala (Sweden); Poggianti, B. M., E-mail: j.m.simpson@dur.ac.uk [INAF-Astronomical Observatory of Padova, I-35122 Padova (Italy); and others

2014-06-20

We present the first photometric redshift distribution for a large sample of 870 μm submillimeter galaxies (SMGs) with robust identifications based on observations with ALMA. In our analysis we consider 96 SMGs in the Extended Chandra Deep Field South, 77 of which have 4-19 band photometry. We model the SEDs for these 77 SMGs, deriving a median photometric redshift of z {sub phot} = 2.3 ± 0.1. The remaining 19 SMGs have insufficient photometry to derive photometric redshifts, but a stacking analysis of Herschel observations confirms they are not spurious. Assuming that these SMGs have an absolute H-band magnitude distribution comparable to that of a complete sample of z ∼ 1-2 SMGs, we demonstrate that they lie at slightly higher redshifts, raising the median redshift for SMGs to z {sub phot} = 2.5 ± 0.2. Critically we show that the proportion of galaxies undergoing an SMG-like phase at z ≥ 3 is at most 35% ± 5% of the total population. We derive a median stellar mass of M {sub *} = (8 ± 1) × 10{sup 10} M {sub ☉}, although there are systematic uncertainties of up to 5 × for individual sources. Assuming that the star formation activity in SMGs has a timescale of ∼100 Myr, we show that their descendants at z ∼ 0 would have a space density and M{sub H} distribution that are in good agreement with those of local ellipticals. In addition, the inferred mass-weighted ages of the local ellipticals broadly agree with the look-back times of the SMG events. Taken together, these results are consistent with a simple model that identifies SMGs as events that form most of the stars seen in the majority of luminous elliptical galaxies at the present day.

An ALMA survey of submillimeter galaxies in the extended Chandra deep field south: The redshift distribution and evolution of submillimeter galaxies

International Nuclear Information System (INIS)

Simpson, J. M.; Swinbank, A. M.; Smail, Ian; Alexander, D. M.; Danielson, A. L. R.; Thomson, A. P.; Brandt, W. N.; Bertoldi, F.; Karim, A.; De Breuck, C.; Chapman, S. C.; Coppin, K. E. K.; Da Cunha, E.; Hodge, J. A.; Schinnerer, E.; Dannerbauer, H.; Greve, T. R.; Ivison, R. J.; Knudsen, K. K.; Poggianti, B. M.

2014-01-01

We present the first photometric redshift distribution for a large sample of 870 μm submillimeter galaxies (SMGs) with robust identifications based on observations with ALMA. In our analysis we consider 96 SMGs in the Extended Chandra Deep Field South, 77 of which have 4-19 band photometry. We model the SEDs for these 77 SMGs, deriving a median photometric redshift of z phot = 2.3 ± 0.1. The remaining 19 SMGs have insufficient photometry to derive photometric redshifts, but a stacking analysis of Herschel observations confirms they are not spurious. Assuming that these SMGs have an absolute H-band magnitude distribution comparable to that of a complete sample of z ∼ 1-2 SMGs, we demonstrate that they lie at slightly higher redshifts, raising the median redshift for SMGs to z phot = 2.5 ± 0.2. Critically we show that the proportion of galaxies undergoing an SMG-like phase at z ≥ 3 is at most 35% ± 5% of the total population. We derive a median stellar mass of M * = (8 ± 1) × 10 10 M ☉ , although there are systematic uncertainties of up to 5 × for individual sources. Assuming that the star formation activity in SMGs has a timescale of ∼100 Myr, we show that their descendants at z ∼ 0 would have a space density and M H distribution that are in good agreement with those of local ellipticals. In addition, the inferred mass-weighted ages of the local ellipticals broadly agree with the look-back times of the SMG events. Taken together, these results are consistent with a simple model that identifies SMGs as events that form most of the stars seen in the majority of luminous elliptical galaxies at the present day.

A Full Year's Chandra Exposure on Sloan Digital Sky Survey Quasars from the Chandra Multiwavelength Project

Science.gov (United States)

Green, Paul J.; Aldcroft, T. L.; Richards, G. T.; Barkhouse, W. A.; Constantin, A.; Haggard, D.; Karovska, M.; Kim, D.-W.; Kim, M.; Vikhlinin, A.; Anderson, S. F.; Mossman, A.; Kashyap, V.; Myers, A. D.; Silverman, J. D.; Wilkes, B. J.; Tananbaum, H.

2009-01-01

We study the spectral energy distributions and evolution of a large sample of optically selected quasars from the Sloan Digital Sky Survey that were observed in 323 Chandra images analyzed by the Chandra Multiwavelength Project. Our highest-confidence matched sample includes 1135 X-ray detected quasars in the redshift range 0.2 3, substantially expanding the known sample. We find no evidence for evolution out to z ~ 5 for either the X-ray photon index Γ or for the ratio of optical/UV to X-ray flux αox. About 10% of detected QSOs show best-fit intrinsic absorbing columns greater than 1022 cm-2, but the fraction might reach ~1/3 if most nondetections are absorbed. We confirm a significant correlation between αox and optical luminosity, but it flattens or disappears for fainter (MB gsim -23) active galactic nucleus (AGN) alone. We report significant hardening of Γ both toward higher X-ray luminosity, and for relatively X-ray loud quasars. These trends may represent a relative increase in nonthermal X-ray emission, and our findings thereby strengthen analogies between Galactic black hole binaries and AGN. For uniformly selected subsamples of narrow-line Seyfert 1s and narrow absorption line QSOs, we find no evidence for unusual distributions of either αox or Γ.

Dark Matter Reality Check: Chandra Casts Cloud On Alternative Theory

Science.gov (United States)

2002-10-01

New evidence from NASA's Chandra X-ray Observatory challenges an alternative theory of gravity that eliminates the need for dark matter. The observation also narrows the field for competing forms of dark matter, the elusive material thought to be the dominant form of matter in the universe. An observation of the galaxy NGC 720 shows it is enveloped in a slightly flattened, or ellipsoidal cloud of hot gas that has an orientation different from that of the optical image of the galaxy. The flattening is too large to be explained by theories in which stars and gas are assumed to contain most of the mass in the galaxy. "The shape and orientation of the hot gas cloud require it to be confined by an egg-shaped dark matter halo," said David Buote of the University of California, Irvine, and lead author of a report on this research in the 2002 September 20 issue of The Astrophysical Journal. "This means that dark matter is not just an illusion due to a shortcoming of the standard theory of gravity - it is real." According to the generally accepted standard theory of gravity, the hot X-ray cloud would need an additional source of gravity - a halo of dark matter - to keep the hot gas from expanding away. The mass of dark matter required would be about five to ten times the mass of the stars in the galaxy. If the dark matter tracked the optical light from the stars in the galaxy, the hot X-ray cloud would be more round than it is. The flattened shape of the hot gas cloud requires a flattened dark matter halo. An alternative theory of gravity called MOND, for Modified Newtonian Dynamics, was proposed in 1983 by Mordecai Milgrom of the Weizmann Institute in Israel, and has remained viable over the years. MOND does away with the need for dark matter by modifying the theory where the acceleration produced by gravity is very small, such as the outskirts of galaxies. However, MOND cannot explain the Chandra observation of NGC 720. This is apparently the first dynamical evidence that

VizieR Online Data Catalog: Cool-core clusters with Chandra obs. (Andrade-Santos+, 2017)

Science.gov (United States)

Andrade-Santos, F.; Jones, C.; Forman, W. R.; Lovisari, L.; Vikhlinin, A.; van Weeren, R. J.; Murray, S. S.; Arnaud, M.; Pratt, G. W.; Democles, J.; Kraft, R.; Mazzotta, P.; Bohringer, H.; Chon, G.; Giacintucci, S.; Clarke, T. E.; Borgani, S.; David, L.; Douspis, M.; Pointecouteau, E.; Dahle, H.; Brown, S.; Aghanim, N.; Rasia, E.

2018-02-01

The main goal of this work is to compare the fraction of cool-core (CC) clusters in X-ray-selected and SZ-selected samples. The first catalog of 189 SZ clusters detected by the Planck mission was released in early 2011 (Planck Collaboration 2011, VIII/88/esz). A Chandra XVP (X-ray Visionary Program--PI: Jones) and HRC Guaranteed Time Observations (PI: Murray) combined to form the Chandra-Planck Legacy Program for Massive Clusters of Galaxies. For each of the 164 ESZ Planck clusters at z<=0.35, we obtained Chandra exposures sufficient to collect at least 10000 source counts. The X-ray sample used here is an extension of the Voevodkin & Vikhlinin (2004ApJ...601..610V) sample. This sample contains 100 clusters and has an effective redshift depth of z<0.3. All have Chandra observations. Of the 100 X-ray-selected clusters, 49 are also in the ESZ sample, and 47 are in the HIFLUGCS (Reiprich & Boehringer 2002ApJ...567..716R) catalog. (2 data files).

M31 in the Chandra Era: A High Definition Movie of a Nearby Galaxy

Science.gov (United States)

Kong, Albert; di Stefano, Rosanne

2009-09-01

M31 has been a prime targets for all X-ray missions since the first detection in 1974. With its superb spatial resolution, Chandra is unique in resolving dense source regions and detecting faint sources. Since the launch of Chandra, M31 has been regularly observed. It is perhaps the only nearby galaxy which is observed by an X-ray telescope regularly throughout operation. With 10 years of observations, the center of M31 has been observed with Chandra for nearly 1 Msec. The X-ray skies of M31 not only consist of many transients and variables, globular cluster X-ray sources in M31 are also different from our Milky Way. They are in general more luminous and one of them may even host an intermediate-mass black hole. Supersoft and quasi-soft X-ray sources in M31 are the best kept secret to unlock the nature of the progenitor of Type Ia supernova. In this talk, I will review some of the important Chandra discoveries in M31 in the past 10 years.

Chandra position of IGR J17454-2919 and discovery of a possible NIR counterpart

DEFF Research Database (Denmark)

Paizis, A.; Nowak, M.; Chati, S.

2015-01-01

On 2014 November 3, we observed the recently discovered INTEGRAL source IGR J17454-2919 (ATels #6530, #6574 and #6602) with Chandra HETGS for 20ks. The J2000.0 Chandra position we obtain is RA: 17 45 27.689 DEC: -29 19 53.83 (90% uncertainty of 0.6") This position (2.4" away from the Swift positi...

The role of Chandra in ten years from now and for the next few decades of astrophysical research

Science.gov (United States)

D'Abrusco, Raffaele; Becker, Glenn E.; McCollough, Michael L.; Rots, Arnold H.; Thong, Sinh A.; Van Stone, David; Winkelman, Sherry

2018-06-01

For almost twenty years, Chandra has advanced our understanding of the X-ray Universe by allowing astronomers to peer into a previously unexplored region of the high-energy observational parameters space. Thanks to its longevity,the mission has accumulated a large, unique body of observations whose legacy value, already tangible at this point, will only increase with time, and whose long-lasting influence extends well beyond the energy interval probed by Chandra. The Chandra archive, through the extensive characterization of the links between observations and literature, has measured the impact of Chandra on the astrophysical literature at a high level of granularity, providing striking evidence of how deeply and widely Chandra has impacted the advancement of both high-energy astrophysics and astronomical research from a multi-wavelength perspective. In this talk, based on the missions that have been submitted for recommendation at the next decadal survey and the possible outcomes of the evaluation process, I will discuss how Chandra archival data can be used to anticipate the projected scientific success and long-lasting effects of a X-ray mission like Lynx or, differently, how they will become instrumental to maximize the scientific output of a new generation of facilities that will observe in different energies. I will argue that, in either scenario, the centrality of Chandra will extend well after the final demise of the mission, and its data will continue serving the community in many different ways for the foreseeable future.

DISSECTING PHOTOMETRIC REDSHIFT FOR ACTIVE GALACTIC NUCLEUS USING XMM- AND CHANDRA-COSMOS SAMPLES

International Nuclear Information System (INIS)

Salvato, M.; Hasinger, G.; Ilbert, O.; Rau, A.; Brusa, M.; Bongiorno, A.; Civano, F.; Elvis, M.; Zamorani, G.; Vignali, C.; Comastri, A.; Bardelli, S.; Bolzonella, M.; Cappelluti, N.; Aussel, H.; Le Floc'h, E.; Fiore, F.; Mainieri, V.; Capak, P.; Caputi, K.

2011-01-01

In this paper, we release accurate photometric redshifts for 1692 counterparts to Chandra sources in the central square degree of the Cosmic Evolution Survey (COSMOS) field. The availability of a large training set of spectroscopic redshifts that extends to faint magnitudes enabled photometric redshifts comparable to the highest quality results presently available for normal galaxies. We demonstrate that morphologically extended, faint X-ray sources without optical variability are more accurately described by a library of normal galaxies (corrected for emission lines) than by active galactic nucleus (AGN) dominated templates, even if these sources have AGN-like X-ray luminosities. Preselecting the library on the bases of the source properties allowed us to reach an accuracy σ Δz/(1+z spec ) ∼0.015 with a fraction of outliers of 5.8% for the entire Chandra-COSMOS sample. In addition, we release revised photometric redshifts for the 1735 optical counterparts of the XMM-detected sources over the entire 2 deg 2 of COSMOS. For 248 sources, our updated photometric redshift differs from the previous release by Δz > 0.2. These changes are predominantly due to the inclusion of newly available deep H-band photometry (H AB = 24 mag). We illustrate once again the importance of a spectroscopic training sample and how an assumption about the nature of a source together, with the number and the depth of the available bands, influences the accuracy of the photometric redshifts determined for AGN. These considerations should be kept in mind when defining the observational strategies of upcoming large surveys targeting AGNs, such as eROSITA at X-ray energies and the Australian Square Kilometre Array Pathfinder Evolutionary Map of the Universe in the radio band.

75 FR 7471 - Chandra Coffee and Rabun Boatworks, Complainants v. Georgia Power Company, Respondent; Notice of...

Science.gov (United States)

2010-02-19

... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Project No. 2354-10] Chandra Coffee and Rabun Boatworks, Complainants v. Georgia Power Company, Respondent; Notice of Complaint February 3, 2010. Take notice that on December 14, 2009, as amended on January 8, 2010, Chandra Coffee and Rabun...

CHANDRA DEEP OBSERVATION OF XDCP J0044.0-2033, A MASSIVE GALAXY CLUSTER AT z > 1.5

Energy Technology Data Exchange (ETDEWEB)

Tozzi, P.; Santos, J. S.; Rosati, P. [INAF-Osservatorio Astrofisico di Arcetri, Largo E. Fermi 5, I-50125 Firenze (Italy); Jee, M. J. [Department of Physics, University of California, Davis One Shields Avenue, Davis, CA 95616-8677 (United States); Fassbender, R. [INAF-Osservatorio Astronomico di Roma (OAR), via Frascati 33, I-00040 Monte Porzio Catone (Italy); Nastasi, A. [Istitut d' Astrophysique Spatiale, CNRS, Bat. 121, Université Paris-Sud, F-91405 Orsay (France); Forman, W.; Jones, C. [Harvard-Smithsonian Center for Astrophysics 60 Garden Street, Cambridge, MA 02138 (United States); Sartoris, B.; Borgani, S. [Università degli Studi di Trieste, Dipartimento di Fisica, Via A.Valerio, 2 I-34127 Trieste (Italy); Boehringer, H. [Max-Planck-Institut fr extraterrestrische Physik Giessenbachstr.1, D-85748 Garching (Germany); Altieri, B. [European Space Astronomy Centre (ESAC), European Space Agency, Apartado de Correos 78, E-28691 Villanueva de la Canada, Madrid (Spain); Pratt, G. W. [CEA Saclay, Service d' Astrophysique, LOrme des Merisiers, Bat. 709, F-91191 Gif-sur-Yvette Cedex (France); Nonino, M. [INAF-Osservatorio Astronomico di Trieste, via G. B. Tiepolo 11, I-34143 Trieste (Italy)

2015-01-20

We report the analysis of the Chandra observation of XDCP J0044.0-2033, a massive, distant (z = 1.579) galaxy cluster discovered in the XDCP survey. The total exposure time of 380 ks with Chandra ACIS-S provides the deepest X-ray observation currently achieved on a massive, high-redshift cluster. Extended emission from the intra cluster medium (ICM) is detected at a very high significance level (S/N ∼ 20) on a circular region with a 44'' radius, corresponding to R {sub ext} = 375 kpc at the cluster redshift. We perform an X-ray spectral fit of the ICM emission modeling the spectrum with a single-temperature thermal mekal model. Our analysis provides a global temperature kT=6.7{sub −0.9}{sup +1.3} keV, and a iron abundance Z{sub Fe}=0.41{sub −0.26}{sup +0.29}Z{sub Fe{sub ⊙}} (error bars correspond to 1σ). We fit the background-subtracted surface brightness profile with a single β-model out to 44'', finding a rather flat profile with no hints of a cool core. We derive the deprojected electron density profile and compute the ICM mass within the extraction radius R {sub ext} = 375 kpc to be M {sub ICM}(r < R {sub ext}) = (1.48 ± 0.20) × 10{sup 13} M {sub ☉}. Under the assumption of hydrostatic equilibrium and assuming isothermality within R {sub ext}, the total mass is M{sub 2500}=1.23{sub −0.27}{sup +0.46}×10{sup 14} M{sub ⊙} for R{sub 2500}=240{sub −20}{sup +30} kpc. Extrapolating the profile at radii larger than the extraction radius R {sub ext} we find M{sub 500}=3.2{sub −0.6}{sup +0.9}×10{sup 14} M{sub ⊙} for R{sub 500}=562{sub −37}{sup +50} kpc. This analysis establishes the existence of virialized, massive galaxy clusters at redshift z ∼ 1.6, paving the way to the investigation of the progenitors of the most massive clusters today. Given its mass and the XDCP survey volume, XDCP J0044.0-2033 does not create significant tension with the WMAP-7 ΛCDM cosmology.

Chandra Cluster Cosmology Project III: Cosmological Parameter Constraints

DEFF Research Database (Denmark)

Vikhlinin, A.; Kravtsov, A. V.; Burenin, R. A.

2009-01-01

function evolution to be used as a useful growth of a structure-based dark energy probe. In this paper, we present cosmological parameter constraints obtained from Chandra observations of 37 clusters with langzrang = 0.55 derived from 400 deg2 ROSAT serendipitous survey and 49 brightest z ≈ 0.05 clusters...

SEDS: THE SPITZER EXTENDED DEEP SURVEY. SURVEY DESIGN, PHOTOMETRY, AND DEEP IRAC SOURCE COUNTS

International Nuclear Information System (INIS)

Ashby, M. L. N.; Willner, S. P.; Fazio, G. G.; Huang, J.-S.; Hernquist, L.; Hora, J. L.; Arendt, R.; Barmby, P.; Barro, G.; Faber, S.; Guhathakurta, P.; Bell, E. F.; Bouwens, R.; Cattaneo, A.; Croton, D.; Davé, R.; Dunlop, J. S.; Egami, E.; Finlator, K.; Grogin, N. A.

2013-01-01

The Spitzer Extended Deep Survey (SEDS) is a very deep infrared survey within five well-known extragalactic science fields: the UKIDSS Ultra-Deep Survey, the Extended Chandra Deep Field South, COSMOS, the Hubble Deep Field North, and the Extended Groth Strip. SEDS covers a total area of 1.46 deg 2 to a depth of 26 AB mag (3σ) in both of the warm Infrared Array Camera (IRAC) bands at 3.6 and 4.5 μm. Because of its uniform depth of coverage in so many widely-separated fields, SEDS is subject to roughly 25% smaller errors due to cosmic variance than a single-field survey of the same size. SEDS was designed to detect and characterize galaxies from intermediate to high redshifts (z = 2-7) with a built-in means of assessing the impact of cosmic variance on the individual fields. Because the full SEDS depth was accumulated in at least three separate visits to each field, typically with six-month intervals between visits, SEDS also furnishes an opportunity to assess the infrared variability of faint objects. This paper describes the SEDS survey design, processing, and publicly-available data products. Deep IRAC counts for the more than 300,000 galaxies detected by SEDS are consistent with models based on known galaxy populations. Discrete IRAC sources contribute 5.6 ± 1.0 and 4.4 ± 0.8 nW m –2 sr –1 at 3.6 and 4.5 μm to the diffuse cosmic infrared background (CIB). IRAC sources cannot contribute more than half of the total CIB flux estimated from DIRBE data. Barring an unexpected error in the DIRBE flux estimates, half the CIB flux must therefore come from a diffuse component.

Multiple sclerosis deep grey matter: the relation between demyelination, neurodegeneration, inflammation and iron.

Science.gov (United States)

Haider, Lukas; Simeonidou, Constantina; Steinberger, Günther; Hametner, Simon; Grigoriadis, Nikolaos; Deretzi, Georgia; Kovacs, Gabor G; Kutzelnigg, Alexandra; Lassmann, Hans; Frischer, Josa M

2014-12-01

In multiple sclerosis (MS), diffuse degenerative processes in the deep grey matter have been associated with clinical disabilities. We performed a systematic study in MS deep grey matter with a focus on the incidence and topographical distribution of lesions in relation to white matter and cortex in a total sample of 75 MS autopsy patients and 12 controls. In addition, detailed analyses of inflammation, acute axonal injury, iron deposition and oxidative stress were performed. MS deep grey matter was affected by two different processes: the formation of focal demyelinating lesions and diffuse neurodegeneration. Deep grey matter demyelination was most prominent in the caudate nucleus and hypothalamus and could already be seen in early MS stages. Lesions developed on the background of inflammation. Deep grey matter inflammation was intermediate between low inflammatory cortical lesions and active white matter lesions. Demyelination and neurodegeneration were associated with oxidative injury. Iron was stored primarily within oligodendrocytes and myelin fibres and released upon demyelination. In addition to focal demyelinated plaques, the MS deep grey matter also showed diffuse and global neurodegeneration. This was reflected by a global reduction of neuronal density, the presence of acutely injured axons, and the accumulation of oxidised phospholipids and DNA in neurons, oligodendrocytes and axons. Neurodegeneration was associated with T cell infiltration, expression of inducible nitric oxide synthase in microglia and profound accumulation of iron. Thus, both focal lesions as well as diffuse neurodegeneration in the deep grey matter appeared to contribute to the neurological disabilities of MS patients. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions.

A High-definition View Of The Circum-nuclear Regions In Nearby Seyferts With Chandra And HST

Science.gov (United States)

Wang, Junfeng; Fabbiano, G.; Elvis, M.; Risaliti, G.; Karovska, M.; Zezas, A.; Mundell, C. G.

2011-09-01

To improve our understanding of AGN feedback, it is crucial to evaluate the true role of outflows on galaxy evolution observationally. I will present new results from the CHandra survey of Extended Emission-line Regions in nearby Seyfert galaxies (CHEERS), which aims to examine feedback in action in much greater detail than at high redshift. Findings from Chandra studies of the circum-nuclear region in the archetypal Seyfert 1 galaxy NGC 4151 will be discussed in detail. Exploiting Chandra's highest possible resolution, we find evidence for X-ray emission from interaction between radio outflow and the optical narrow-line region clouds, in addition to the emission from photoionized gas.

The Chandra M10l Megasecond: Diffuse Emission

Science.gov (United States)

Kuntz, K. D.; Snowden, S. L.

2009-01-01

Because MIOl is nearly face-on, it provides an excellent laboratory in which to study the distribution of X-ray emitting gas in a typical late-type spiral galaxy. We obtained a Chandra observation with a cumulative exposure of roughly 1 Ms to study the diffuse X-ray emission in MlOl. The bulk of the X-ray emission is correlated with the star formation traced by the FUV emission. The global FUV/Xray correlation is non-linear (the X-ray surface brightness is roughly proportional to the square root of the FUV surface brightness) and the small-scale correlation is poor, probably due to the delay between the FUV emission and the X-ray production ill star-forming regions. The X-ray emission contains only minor contributions from unresolved stars (approximates less than 3%), unresolved X-ray point sources (approximates less than 4%), and individual supernova remnants (approximates 3%). The global spectrum of the diffuse emission can be reasonably well fitted with a three component thermal model, but the fitted temperatures are not unique; many distributions of emission measure can produce the same temperatures when observed with the current CCD energy resolution. The spectrum of the diffuse emission depends on the environment; regions with higher X-ray surface brightnesses have relatively stronger hard components, but there is no significant evidence that the temperatures of the emitting components increase with surface brightness.

The Chandra Source Catalog 2.0: Building The Catalog

Science.gov (United States)

Grier, John D.; Plummer, David A.; Allen, Christopher E.; Anderson, Craig S.; Budynkiewicz, Jamie A.; Burke, Douglas; Chen, Judy C.; Civano, Francesca Maria; D'Abrusco, Raffaele; Doe, Stephen M.; Evans, Ian N.; Evans, Janet D.; Fabbiano, Giuseppina; Gibbs, Danny G., II; Glotfelty, Kenny J.; Graessle, Dale E.; Hain, Roger; Hall, Diane M.; Harbo, Peter N.; Houck, John C.; Lauer, Jennifer L.; Laurino, Omar; Lee, Nicholas P.; Martínez-Galarza, Juan Rafael; McCollough, Michael L.; McDowell, Jonathan C.; Miller, Joseph; McLaughlin, Warren; Morgan, Douglas L.; Mossman, Amy E.; Nguyen, Dan T.; Nichols, Joy S.; Nowak, Michael A.; Paxson, Charles; Primini, Francis Anthony; Rots, Arnold H.; Siemiginowska, Aneta; Sundheim, Beth A.; Tibbetts, Michael; Van Stone, David W.; Zografou, Panagoula

2018-01-01

To build release 2.0 of the Chandra Source Catalog (CSC2), we require scientific software tools and processing pipelines to evaluate and analyze the data. Additionally, software and hardware infrastructure is needed to coordinate and distribute pipeline execution, manage data i/o, and handle data for Quality Assurance (QA) intervention. We also provide data product staging for archive ingestion.Release 2 utilizes a database driven system used for integration and production. Included are four distinct instances of the Automatic Processing (AP) system (Source Detection, Master Match, Source Properties and Convex Hulls) and a high performance computing (HPC) cluster that is managed to provide efficient catalog processing. In this poster we highlight the internal systems developed to meet the CSC2 challenge.This work has been supported by NASA under contract NAS 8-03060 to the Smithsonian Astrophysical Observatory for operation of the Chandra X-ray Center.

Initial Performance of the Attitude Control and Aspect Determination Subsystems on the Chandra Observatory

Science.gov (United States)

Cameron, R.; Aldcroft, T.; Podgorski, W. A.; Freeman, M. D.

2000-01-01

The aspect determination system of the Chandra X-ray Observatory plays a key role in realizing the full potential of Chandra's X-ray optics and detectors. We review the performance of the spacecraft hardware components and sub-systems, which provide information for both real time control of the attitude and attitude stability of the Chandra Observatory and also for more accurate post-facto attitude reconstruction. These flight components are comprised of the aspect camera (star tracker) and inertial reference units (gyros), plus the fiducial lights and fiducial transfer optics which provide an alignment null reference system for the science instruments and X-ray optics, together with associated thermal and structural components. Key performance measures will be presented for aspect camera focal plane data, gyro performance both during stable pointing and during maneuvers, alignment stability and mechanism repeatability.

Deepest X-Rays Ever Reveal universe Teeming With Black Holes

Science.gov (United States)

2001-03-01

For the first time, astronomers believe they have proof black holes of all sizes once ruled the universe. NASA's Chandra X-ray Observatory provided the deepest X-ray images ever recorded, and those pictures deliver a novel look at the past 12 billion years of black holes. Two independent teams of astronomers today presented images that contain the faintest X-ray sources ever detected, which include an abundance of active super massive black holes. "The Chandra data show us that giant black holes were much more active in the past than at present," said Riccardo Giacconi, of Johns Hopkins University and Associated Universities, Inc., Washington, DC. The exposure is known as "Chandra Deep Field South" since it is located in the Southern Hemisphere constellation of Fornax. "In this million-second image, we also detect relatively faint X-ray emission from galaxies, groups, and clusters of galaxies". The images, known as Chandra Deep Fields, were obtained during many long exposures over the course of more than a year. Data from the Chandra Deep Field South will be placed in a public archive for scientists beginning today. "For the first time, we are able to use X-rays to look back to a time when normal galaxies were several billion years younger," said Ann Hornschemeier, Pennsylvania State University, University Park. The group’s 500,000-second exposure included the Hubble Deep Field North, allowing scientists the opportunity to combine the power of Chandra and the Hubble Space Telescope, two of NASA's Great Observatories. The Penn State team recently acquired an additional 500,000 seconds of data, creating another one-million-second Chandra Deep Field, located in the constellation of Ursa Major. Chandra Deep Field North/Hubble Deep Field North Press Image and Caption The images are called Chandra Deep Fields because they are comparable to the famous Hubble Deep Field in being able to see further and fainter objects than any image of the universe taken at X

Real Time Space Weather Support for Chandra X-ray Observatory Operations

Science.gov (United States)

O'Dell, S. L.; Miller, S.; Minow, J. I.; Wolk, S.; Aldcroft, T. L.; Spitzbart, B. D.; Swartz, D. A.

2012-12-01

NASA launched the Chandra X-ray Observatory in July 1999. Soon after first light in August 1999, however, degradation in the energy resolution and charge transfer efficiency of the Advanced CCD Imaging Spectrometer (ACIS) x-ray detectors was observed. The source of the degradation was quickly identified as radiation damage in the charge-transfer channel of the front-illuminated CCDs, by weakly penetrating ("soft", 100-500 keV) protons as Chandra passed through the Earth's radiation belts and ring currents. As soft protons were not considered a risk to spacecraft health before launch, the only on-board radiation monitoring system is the Electron, Proton, and Helium Instrument (EPHIN) which was included on Chandra with the primary purpose of monitoring energetic solar particle events. Further damage to the ACIS detector has been successfully mitigated through a combination of careful mission planning, autonomous on-board radiation protection, and manual intervention based upon real-time monitoring of the soft-proton environment. The AE-8 and AP-8 trapped radiation models and Chandra Radiation Models are used to schedule science operations in regions of low proton flux. EPHIN has been used as the primary autonomous in-situ radiation trigger; but, it is not sensitive to the soft protons that damage the front-illuminated CCDs. Monitoring of near-real-time space weather data sources provides critical information on the proton environment outside the Earth's magnetosphere due to solar proton events and other phenomena. The operations team uses data from the Geostationary Operational Environmental Satellites (GOES) to provide near-real-time monitoring of the proton environment; however, these data do not give a representative measure of the soft-proton (real-time data provided by NOAA's Space Weather Prediction Center. This presentation will discuss radiation mitigation against proton damage, including models and real-time data sources used to protect the ACIS detector

The Chandra Source Catalog 2.0: Spectral Properties

Science.gov (United States)

McCollough, Michael L.; Siemiginowska, Aneta; Burke, Douglas; Nowak, Michael A.; Primini, Francis Anthony; Laurino, Omar; Nguyen, Dan T.; Allen, Christopher E.; Anderson, Craig S.; Budynkiewicz, Jamie A.; Chen, Judy C.; Civano, Francesca Maria; D'Abrusco, Raffaele; Doe, Stephen M.; Evans, Ian N.; Evans, Janet D.; Fabbiano, Giuseppina; Gibbs, Danny G., II; Glotfelty, Kenny J.; Graessle, Dale E.; Grier, John D.; Hain, Roger; Hall, Diane M.; Harbo, Peter N.; Houck, John C.; Lauer, Jennifer L.; Lee, Nicholas P.; Martínez-Galarza, Juan Rafael; McDowell, Jonathan C.; Miller, Joseph; McLaughlin, Warren; Morgan, Douglas L.; Mossman, Amy E.; Nichols, Joy S.; Paxson, Charles; Plummer, David A.; Rots, Arnold H.; Sundheim, Beth A.; Tibbetts, Michael; Van Stone, David W.; Zografou, Panagoula; Chandra Source Catalog Team

2018-01-01

The second release of the Chandra Source Catalog (CSC) contains all sources identified from sixteen years' worth of publicly accessible observations. The vast majority of these sources have been observed with the ACIS detector and have spectral information in 0.5-7 keV energy range. Here we describe the methods used to automatically derive spectral properties for each source detected by the standard processing pipeline and included in the final CSC. The sources with high signal to noise ratio (exceeding 150 net counts) were fit in Sherpa (the modeling and fitting application from the Chandra Interactive Analysis of Observations package) using wstat as a fit statistic and Bayesian draws method to determine errors. Three models were fit to each source: an absorbed power-law, blackbody, and Bremsstrahlung emission. The fitted parameter values for the power-law, blackbody, and Bremsstrahlung models were included in the catalog with the calculated flux for each model. The CSC also provides the source energy fluxes computed from the normalizations of predefined absorbed power-law, black-body, Bremsstrahlung, and APEC models needed to match the observed net X-ray counts. For sources that have been observed multiple times we performed a Bayesian Blocks analysis will have been performed (see the Primini et al. poster) and the most significant block will have a joint fit performed for the mentioned spectral models. In addition, we provide access to data products for each source: a file with source spectrum, the background spectrum, and the spectral response of the detector. Hardness ratios were calculated for each source between pairs of energy bands (soft, medium and hard). This work has been supported by NASA under contract NAS 8-03060 to the Smithsonian Astrophysical Observatory for operation of the Chandra X-ray Center.

Modeling Contamination Migration on the Chandra X-ray Observatory II

Science.gov (United States)

O'Dell, Steve; Swartz, Doug; Tice, Neil; Plucinsky, Paul; Grant, Catherine; Marshall, Herman; Vikhlinin, Alexey

2013-01-01

During its first 14 years of operation, the cold (about -60degC) optical blocking filter of the Advanced CCD Imaging Spectrometer (ACIS), aboard the Chandra X-ray Observatory, has accumulated a growing layer of molecular contamination that attenuates low-energy x rays. Over the past few years, the accumulation rate, spatial distribution, and composition may have changed, perhaps partially related to changes in the operating temperature of the ACIS housing. This evolution of the accumulation of the molecular contamination has motivated further analysis of contamination migration on the Chandra X-ray Observatory, particularly within and near the ACIS cavity. To this end, the current study employs a higher-fidelity geometric model of the ACIS cavity, detailed thermal modeling based upon monitored temperature data, and an accordingly refined model of the molecular transport.

Determinants of iron accumulation in deep grey matter of multiple sclerosis patients

DEFF Research Database (Denmark)

Ropele, Stefan; Kilsdonk, Iris D; Wattjes, Mike P

2014-01-01

BACKGROUND: Iron accumulation in deep grey matter (GM) structures is a consistent finding in multiple sclerosis (MS) patients. This study focused on the identification of independent determinants of iron accumulation using R2* mapping. SUBJECTS AND METHODS: Ninety-seven MS patients and 81 healthy...... controls were included in this multicentre study. R2* mapping was performed on 3T MRI systems. R2*in deep GM was corrected for age and was related to disease duration, disability, T2 lesion load and brain volume. RESULTS: Compared to controls, R2* was increased in all deep GM regions of MS patients except...... and the red nucleus. In lesions, R2* was inversely correlated with disease duration and higher total lesion load. CONCLUSION: Iron accumulation in deep GM of MS patients is most strongly and independently associated with duration and severity of the disease. Additional associations between cortical GM atrophy...

Chandra X-ray observations of the hyper-luminous infrared galaxy IRAS F15307+3252

Science.gov (United States)

Hlavacek-Larrondo, J.; Gandhi, P.; Hogan, M. T.; Gendron-Marsolais, M.-L.; Edge, A. C.; Fabian, A. C.; Russell, H. R.; Iwasawa, K.; Mezcua, M.

2017-01-01

Hyper-luminous infrared galaxies (HyLIRGs) lie at the extreme luminosity end of the IR galaxy population with LIR > 1013 L⊙. They are thought to be closer counterparts of the more distant sub-millimeter galaxies, and should therefore be optimal targets to study the most massive systems in formation. We present deep Chandra observations of IRAS F15307+3252 (100 ks), a classical HyLIRG located at z = 0.93 and hosting a radio-loud AGN (L1.4 GHz ˜ 3.5 × 1025 W Hz-1). The Chandra images reveal the presence of extended (r = 160 kpc), asymmetric X-ray emission in the soft 0.3-2.0 keV band that has no radio counterpart. We therefore argue that the emission is of thermal origin originating from a hot intragroup or intracluster medium virializing in the potential. We find that the temperature (˜2 keV) and bolometric X-ray luminosity (˜3 × 1043 erg s-1) of the gas follow the expected LX-ray-T correlation for groups and clusters, and that the gas has a remarkably short cooling time of 1.2 Gyr. In addition, VLA radio observations reveal that the galaxy hosts an unresolved compact steep-spectrum (CSS) source, most likely indicating the presence of a young radio source similar to 3C186. We also confirm that the nucleus is dominated by a redshifted 6.4 keV Fe Kα line, strongly suggesting that the AGN is Compton-thick. Finally, Hubble images reveal an overdensity of galaxies and sub-structure in the galaxy that correlates with soft X-ray emission. This could be a snapshot view of on-going groupings expected in a growing cluster environment. IRAS F15307+3252 might therefore be a rare example of a group in the process of transforming into a cluster.

CHANDRA X-RAY DETECTION OF THE ENIGMATIC FIELD STAR BP Psc

International Nuclear Information System (INIS)

Kastner, Joel H.; Montez, Rodolfo; Rodriguez, David; Zuckerman, B.; Perrin, Marshall D.; Grosso, Nicolas; Forveille, Thierry; Graham, James R.

2010-01-01

BP Psc is a remarkable emission-line field star that is orbited by a dusty disk and drives a parsec-scale system of jets. We report the detection by the Chandra X-ray Observatory of a weak X-ray point source coincident with the centroids of optical/IR and submillimeter continuum emission at BP Psc. As the star's photosphere is obscured throughout the visible and near-infrared, the Chandra X-ray source likely represents the first detection of BP Psc itself. The X-rays most likely originate with magnetic activity at BP Psc and hence can be attributed either to a stellar corona or to star-disk interactions. The log of the ratio of X-ray to bolometric luminosity, log(L X /L bol ), lies in the range -5.8 to -4.2. This is smaller than log(L X /L bol ) ratios typical of low-mass, pre-main sequence stars, but is well within the log(L X /L bol ) range observed for rapidly rotating (FK Com-type) G giant stars. Hence, the Chandra results favor an exotic model wherein the disk/jet system of BP Psc is the result of its very recently engulfing a companion star or a giant planet, as the primary star ascended the giant branch.

Deep Extragalactic VIsible Legacy Survey (DEVILS): Motivation, Design and Target Catalogue

Science.gov (United States)

Davies, L. J. M.; Robotham, A. S. G.; Driver, S. P.; Lagos, C. P.; Cortese, L.; Mannering, E.; Foster, C.; Lidman, C.; Hashemizadeh, A.; Koushan, S.; O'Toole, S.; Baldry, I. K.; Bilicki, M.; Bland-Hawthorn, J.; Bremer, M. N.; Brown, M. J. I.; Bryant, J. J.; Catinella, B.; Croom, S. M.; Grootes, M. W.; Holwerda, B. W.; Jarvis, M. J.; Maddox, N.; Meyer, M.; Moffett, A. J.; Phillipps, S.; Taylor, E. N.; Windhorst, R. A.; Wolf, C.

2018-06-01

The Deep Extragalactic VIsible Legacy Survey (DEVILS) is a large spectroscopic campaign at the Anglo-Australian Telescope (AAT) aimed at bridging the near and distant Universe by producing the highest completeness survey of galaxies and groups at intermediate redshifts (0.3 < z < 1.0). Our sample consists of ˜60,000 galaxies to Y<21.2 mag, over ˜6 deg2 in three well-studied deep extragalactic fields (Cosmic Origins Survey field, COSMOS, Extended Chandra Deep Field South, ECDFS and the X-ray Multi-Mirror Mission Large-Scale Structure region, XMM-LSS - all Large Synoptic Survey Telescope deep-drill fields). This paper presents the broad experimental design of DEVILS. Our target sample has been selected from deep Visible and Infrared Survey Telescope for Astronomy (VISTA) Y-band imaging (VISTA Deep Extragalactic Observations, VIDEO and UltraVISTA), with photometry measured by PROFOUND. Photometric star/galaxy separation is done on the basis of NIR colours, and has been validated by visual inspection. To maximise our observing efficiency for faint targets we employ a redshift feedback strategy, which continually updates our target lists, feeding back the results from the previous night's observations. We also present an overview of the initial spectroscopic observations undertaken in late 2017 and early 2018.

TGCat : THE CHANDRA TRANSMISSION GRATING DATA CATALOG AND ARCHIVE

International Nuclear Information System (INIS)

Huenemoerder, David P.; Dewey, Daniel; Nowak, Michael A.; Schulz, Norbert S.; Davis, John E.; Houck, John C.; Marshall, Herman L.; Noble, Michael S.; Canizares, Claude R.; Mitschang, Arik; Nichols, Joy S.; Morgan, Doug

2011-01-01

The Chandra Transmission Grating Data Archive and Catalog (TGCat) provides easy access to analysis-ready products, specifically, high-resolution X-ray count spectra and their corresponding calibrations. The web interface makes it easy to find observations of a particular object, type of object, or type of observation; to quickly assess the quality and potential usefulness of the spectra from pre-computed summary plots; or to customize a view with an interactive plotter, optionally combining spectra over multiple orders or observations. Data and responses can be downloaded as a package or as individual files, and the query results themselves can be retrieved as ASCII or Virtual Observatory tables. Portable reprocessing scripts used to create the archive and which use the Chandra X-ray Center's (CXC's) software and other publicly available software are also available, facilitating standard or customized reprocessing from Level 1 CXC archival data to spectra and responses with minimal user interaction.

SELDI-TOF MS of quadruplicate urine and serum samples to evaluate changes related to storage conditions.

Science.gov (United States)

Traum, Avram Z; Wells, Meghan P; Aivado, Manuel; Libermann, Towia A; Ramoni, Marco F; Schachter, Asher D

2006-03-01

Proteomic profiling with SELDI-TOF MS has facilitated the discovery of disease-specific protein profiles. However, multicenter studies are often hindered by the logistics required for prompt deep-freezing of samples in liquid nitrogen or dry ice within the clinic setting prior to shipping. We report high concordance between MS profiles within sets of quadruplicate split urine and serum samples deep-frozen at 0, 2, 6, and 24 h after sample collection. Gage R&R results confirm that deep-freezing times are not a statistically significant source of SELDI-TOF MS variability for either blood or urine.

Action at the Horizon: Chandra/EHT Observations of Sgr A*

Science.gov (United States)

Neilsen, Joseph

2017-09-01

In April 2017, the Event Horizon Telescope will observe Sgr A* with imaging quality sufficient to resolve the shadow of the black hole, while providing a close-up view of accretion at the horizon. As Sgr A* is a well-known source of X-ray flares, coordinated Chandra/EHT observations offer an incredible opportunity: a chance to observe structures (e.g., hotspots) near the event horizon while tracking their high-energy variability. In anticipation of a follow-up campaign in 2018, we are requesting 4x33 ks Chandra observations of Sgr A* to be coordinated with EHT. This campaign will double our chances of simultaneous flares. We will search for flares and hotspots, provide priors for EHT image reconstruction, and track any activity associated with the closest approach of the massive star S0-2.

THE CHANDRA SURVEY OF EXTRAGALACTIC SOURCES IN THE 3CR CATALOG: X-RAY EMISSION FROM NUCLEI, JETS, AND HOTSPOTS IN THE CHANDRA ARCHIVAL OBSERVATIONS

Energy Technology Data Exchange (ETDEWEB)

Massaro, F. [Dipartimento di Fisica, Università degli Studi di Torino, via Pietro Giuria 1, I-10125 Torino (Italy); Harris, D. E.; Paggi, A.; Wilkes, B. J.; Kuraszkiewicz, J. [Smithsonian Astrophysical Observatory, 60 Garden Street, Cambridge, MA 02138 (United States); Liuzzo, E.; Orienti, M.; Paladino, R. [Istituto di Radioastronomia, INAF, via Gobetti 101, I-40129, Bologna (Italy); Tremblay, G. R. [Yale Center for Astronomy and Astrophysics, Physics Department, Yale University, P.O. Box 208120, New Haven, CT 06520-8120 (United States); Baum, S. A.; O’Dea, C. P. [University of Manitoba, Dept of Physics and Astronomy, Winnipeg, MB R3T 2N2 (Canada)

2015-09-15

As part of our program to build a complete radio and X-ray database of all Third Cambridge catalog extragalactic radio sources, we present an analysis of 93 sources for which Chandra archival data are available. Most of these sources have already been published. Here we provide a uniform re-analysis and present nuclear X-ray fluxes and X-ray emission associated with radio jet knots and hotspots using both publicly available radio images and new radio images that have been constructed from data available in the Very Large Array archive. For about 1/3 of the sources in the selected sample, a comparison between the Chandra and radio observations was not reported in the literature: we find X-ray detections of 2 new radio jet knots and 17 hotspots. We also report the X-ray detection of extended emission from the intergalactic medium for 15 galaxy clusters.

Chandra Captures Venus In A Whole New Light

Science.gov (United States)

2001-11-01

Scientists have captured the first X-ray view of Venus using NASA's Chandra X-ray Observatory. The observations provide new information about the atmosphere of Venus and open a new window for examining Earth's sister planet. Venus in X-rays looks similar to Venus in visible light, but there are important differences. The optically visible Venus is due to the reflection of sunlight and, for the relative positions of Venus, Earth and Sun during these observations, shows a uniform half-crescent that is brightest toward the middle. The X-ray Venus is slightly less than a half-crescent and brighter on the limbs. The differences are due to the processes by which Venus shines in visible and X-ray light. The X-rays from Venus are produced by fluorescence, rather than reflection. Solar X-rays bombard the atmosphere of Venus, knock electrons out of the inner parts of the atoms, and excite the atoms to a higher energy level. The atoms almost immediately return to their lower energy state with the emission of a fluorescent X-ray. A similar process involving ultraviolet light produces the visible light from fluorescent lamps. For Venus, most of the fluorescent X-rays come from oxygen and carbon atoms between 120 and 140 kilometers (74 to 87 miles) above the planet's surface. In contrast, the optical light is reflected from clouds at a height of 50 to 70 kilometers (31 to 43 miles). As a result, Venus' Sun-lit hemisphere appears surrounded by an almost-transparent luminous shell in X-rays. Venus looks brightest at the limb since more luminous material is there. Venus X-ray/Optical Composite of Venus Credit: Xray: NASA/CXC/MPE/K.Dennerl et al., Optical: Konrad Dennerl "This opens up the exciting possibility of using X-ray observations to study regions of the atmosphere of Venus that are difficult to investigate by other means," said Konrad Dennerl of the Max Planck Institute for Extraterrestrial Physics in Garching, Germany, leader of an international team of scientists that

Chandra Finds Ghosts Of Eruption In Galaxy Cluster

Science.gov (United States)

2002-01-01

"Ghostly" relics of an ancient eruption that tore through a cluster of galaxies were recently uncovered by NASA's Chandra X-ray Observatory. The discovery implies that galaxy clusters are the sites of enormously energetic and recurring explosions, and may provide an explanation why galaxy clusters behave like giant cosmic magnets. "Chandra's image revealed vast regions in the galaxy cluster Abell 2597 that contain almost no X-ray or radio emission. We call them ghost cavities," said Brian McNamara of Ohio University in Athens today during a press conference at the American Astronomical Society meeting in Washington. "They appear to be remnants of an old explosion where the radio emission has faded away over millions of years." The ghost cavities were likely created by extremely powerful explosions, due to material falling toward a black hole millions of times more massive than the Sun. As the matter swirled around the black hole, located in a galaxy near the center of the cluster, it generated enormous electromagnetic fields that expelled material from the vicinity of the black hole at high speeds. This explosive activity in Abell 2597 created jets of highly energetic particles that cleared out voids in the hot gas. Because they are lighter than the surrounding material, the cavities will eventually push their way to the edge of the cluster, just as air bubbles in water make their way to the surface. Researchers also found evidence that this explosion was not a one-time event. "We detected a small, bright radio source near the center of the cluster that indicates a new explosion has occurred recently," said team member Michael Wise of the Massachusetts Institute of Technology in Cambridge, "so the cycle of eruption is apparently continuing." Though dim, the ghost cavities are not completely empty. They contain a mixture of very hot gas, high-energy particles and magnetic fields -- otherwise the cavities would have collapsed under the pressure of the surrounding hot

THE CHANDRA SOURCE CATALOG

International Nuclear Information System (INIS)

Evans, Ian N.; Primini, Francis A.; Glotfelty, Kenny J.; Anderson, Craig S.; Bonaventura, Nina R.; Chen, Judy C.; Doe, Stephen M.; Evans, Janet D.; Fabbiano, Giuseppina; Galle, Elizabeth C.; Gibbs, Danny G.; Grier, John D.; Hain, Roger M.; Harbo, Peter N.; He Xiangqun; Karovska, Margarita; Kashyap, Vinay L.; Davis, John E.; Houck, John C.; Hall, Diane M.

2010-01-01

The Chandra Source Catalog (CSC) is a general purpose virtual X-ray astrophysics facility that provides access to a carefully selected set of generally useful quantities for individual X-ray sources, and is designed to satisfy the needs of a broad-based group of scientists, including those who may be less familiar with astronomical data analysis in the X-ray regime. The first release of the CSC includes information about 94,676 distinct X-ray sources detected in a subset of public Advanced CCD Imaging Spectrometer imaging observations from roughly the first eight years of the Chandra mission. This release of the catalog includes point and compact sources with observed spatial extents ∼<30''. The catalog (1) provides access to the best estimates of the X-ray source properties for detected sources, with good scientific fidelity, and directly supports scientific analysis using the individual source data; (2) facilitates analysis of a wide range of statistical properties for classes of X-ray sources; and (3) provides efficient access to calibrated observational data and ancillary data products for individual X-ray sources, so that users can perform detailed further analysis using existing tools. The catalog includes real X-ray sources detected with flux estimates that are at least 3 times their estimated 1σ uncertainties in at least one energy band, while maintaining the number of spurious sources at a level of ∼<1 false source per field for a 100 ks observation. For each detected source, the CSC provides commonly tabulated quantities, including source position, extent, multi-band fluxes, hardness ratios, and variability statistics, derived from the observations in which the source is detected. In addition to these traditional catalog elements, for each X-ray source the CSC includes an extensive set of file-based data products that can be manipulated interactively, including source images, event lists, light curves, and spectra from each observation in which a

The Chandra Source Catalog

Science.gov (United States)

Evans, Ian N.; Primini, Francis A.; Glotfelty, Kenny J.; Anderson, Craig S.; Bonaventura, Nina R.; Chen, Judy C.; Davis, John E.; Doe, Stephen M.; Evans, Janet D.; Fabbiano, Giuseppina; Galle, Elizabeth C.; Gibbs, Danny G., II; Grier, John D.; Hain, Roger M.; Hall, Diane M.; Harbo, Peter N.; He, Xiangqun Helen; Houck, John C.; Karovska, Margarita; Kashyap, Vinay L.; Lauer, Jennifer; McCollough, Michael L.; McDowell, Jonathan C.; Miller, Joseph B.; Mitschang, Arik W.; Morgan, Douglas L.; Mossman, Amy E.; Nichols, Joy S.; Nowak, Michael A.; Plummer, David A.; Refsdal, Brian L.; Rots, Arnold H.; Siemiginowska, Aneta; Sundheim, Beth A.; Tibbetts, Michael S.; Van Stone, David W.; Winkelman, Sherry L.; Zografou, Panagoula

2010-07-01

The Chandra Source Catalog (CSC) is a general purpose virtual X-ray astrophysics facility that provides access to a carefully selected set of generally useful quantities for individual X-ray sources, and is designed to satisfy the needs of a broad-based group of scientists, including those who may be less familiar with astronomical data analysis in the X-ray regime. The first release of the CSC includes information about 94,676 distinct X-ray sources detected in a subset of public Advanced CCD Imaging Spectrometer imaging observations from roughly the first eight years of the Chandra mission. This release of the catalog includes point and compact sources with observed spatial extents lsim30''. The catalog (1) provides access to the best estimates of the X-ray source properties for detected sources, with good scientific fidelity, and directly supports scientific analysis using the individual source data; (2) facilitates analysis of a wide range of statistical properties for classes of X-ray sources; and (3) provides efficient access to calibrated observational data and ancillary data products for individual X-ray sources, so that users can perform detailed further analysis using existing tools. The catalog includes real X-ray sources detected with flux estimates that are at least 3 times their estimated 1σ uncertainties in at least one energy band, while maintaining the number of spurious sources at a level of lsim1 false source per field for a 100 ks observation. For each detected source, the CSC provides commonly tabulated quantities, including source position, extent, multi-band fluxes, hardness ratios, and variability statistics, derived from the observations in which the source is detected. In addition to these traditional catalog elements, for each X-ray source the CSC includes an extensive set of file-based data products that can be manipulated interactively, including source images, event lists, light curves, and spectra from each observation in which a

Assess, compare and enhance the status of Persons with Multiple Sclerosis (MS) in Europe

DEFF Research Database (Denmark)

Pugliatti, M; Eskic, D; Mikolcić, T

2012-01-01

Persons with multiple sclerosis (PwMS) experience health-related quality of life (HRQoL) problems greatly differing across Europe, and the European Union (EU) faces deep inequalities in MS management from country to country. Through the establishment of a European MS Register (EUReMS), an effective...

Real Time Space Weather Support for Chandra X-Ray Observatory Operations

Science.gov (United States)

O'Dell, Stephen L.; Minow, Joseph I.; Miller, J. Scott; Wolk, Scott J.; Aldcroft, Thomas L.; Spitzbart, Bradley D.; Swartz. Douglas A.

2012-01-01

NASA launched the Chandra X-ray Observatory in July 1999. Soon after first light in August 1999, however, degradation in the energy resolution and charge transfer efficiency of the Advanced CCD Imaging Spectrometer (ACIS) x-ray detectors was observed. The source of the degradation was quickly identified as radiation damage in the charge-transfer channel of the front-illuminated CCDs, by weakly penetrating ( soft , 100 500 keV) protons as Chandra passed through the Earth s radiation belts and ring currents. As soft protons were not considered a risk to spacecraft health before launch, the only on-board radiation monitoring system is the Electron, Proton, and Helium Instrument (EPHIN) which was included on Chandra with the primary purpose of monitoring energetic solar particle events. Further damage to the ACIS detector has been successfully mitigated through a combination of careful mission planning, autonomous on-board radiation protection, and manual intervention based upon real-time monitoring of the soft-proton environment. The AE-8 and AP-8 trapped radiation models and Chandra Radiation Models are used to schedule science operations in regions of low proton flux. EPHIN has been used as the primary autonomous in-situ radiation trigger; but, it is not sensitive to the soft protons that damage the front-illuminated CCDs. Monitoring of near-real-time space weather data sources provides critical information on the proton environment outside the Earth s magnetosphere due to solar proton events and other phenomena. The operations team uses data from the Geostationary Operational Environmental Satellites (GOES) to provide near-real-time monitoring of the proton environment; however, these data do not give a representative measure of the soft-proton (real-time data provided by NOAA s Space Weather Prediction Center. This presentation describes the radiation mitigation strategies to minimize the proton damage in the ACIS CCD detectors and the importance of real-time data

The Chandra Source Catalog : Automated Source Correlation

Science.gov (United States)

Hain, Roger; Evans, I. N.; Evans, J. D.; Glotfelty, K. J.; Anderson, C. S.; Bonaventura, N. R.; Chen, J. C.; Davis, J. E.; Doe, S. M.; Fabbiano, G.; Galle, E.; Gibbs, D. G.; Grier, J. D.; Hall, D. M.; Harbo, P. N.; He, X.; Houck, J. C.; Karovska, M.; Lauer, J.; McCollough, M. L.; McDowell, J. C.; Miller, J. B.; Mitschang, A. W.; Morgan, D. L.; Nichols, J. S.; Nowak, M. A.; Plummer, D. A.; Primini, F. A.; Refsdal, B. L.; Rots, A. H.; Siemiginowska, A. L.; Sundheim, B. A.; Tibbetts, M. S.; Van Stone, D. W.; Winkelman, S. L.; Zografou, P.

2009-01-01

Chandra Source Catalog (CSC) master source pipeline processing seeks to automatically detect sources and compute their properties. Since Chandra is a pointed mission and not a sky survey, different sky regions are observed for a different number of times at varying orientations, resolutions, and other heterogeneous conditions. While this provides an opportunity to collect data from a potentially large number of observing passes, it also creates challenges in determining the best way to combine different detection results for the most accurate characterization of the detected sources. The CSC master source pipeline correlates data from multiple observations by updating existing cataloged source information with new data from the same sky region as they become available. This process sometimes leads to relatively straightforward conclusions, such as when single sources from two observations are similar in size and position. Other observation results require more logic to combine, such as one observation finding a single, large source and another identifying multiple, smaller sources at the same position. We present examples of different overlapping source detections processed in the current version of the CSC master source pipeline. We explain how they are resolved into entries in the master source database, and examine the challenges of computing source properties for the same source detected multiple times. Future enhancements are also discussed. This work is supported by NASA contract NAS8-03060 (CXC).

Chandra: Ten Years of Amazing Science with a Great Observatory

Science.gov (United States)

Weisskopf, Martin C.

2009-01-01

We review briefly review the history of the development of the Chandra X-Ray Observatory, highlighting certain details that many attendees of this Conference might not be aware of. We then present a selection of scientific highlights of the first 10 years of this remarkable and unique mission.

Nustar and Chandra Insight into the Nature of the 3-40 Kev Nuclear Emission in Ngc 253

Science.gov (United States)

Lehmer, Bret D.; Wik, Daniel R.; Hornschemeier, Ann E.; Ptak, Andrew; Antoniu, V.; Argo, M.K.; Bechtol, K.; Boggs, S.; Christensen, F.E.; Craig, W.W.;

A PUBLIC, K-SELECTED, OPTICAL-TO-NEAR-INFRARED CATALOG OF THE EXTENDED CHANDRA DEEP FIELD SOUTH (ECDFS) FROM THE MULTIWAVELENGTH SURVEY BY YALE-CHILE (MUSYC)

International Nuclear Information System (INIS)

Taylor, Edward N.; Franx, Marijn; Quadri, Ryan F.; Damen, Maaike; Hildebrandt, Hendrik; Van Dokkum, Pieter G.; Herrera, David; Gawiser, Eric; Bell, Eric F.; Barrientos, L. Felipe; Blanc, Guillermo A.; Castander, Francisco J.; Gonzalez-Perez, Violeta; Hall, Patrick B.; Kriek, Mariska; Labbe, Ivo; Lira, Paulina; Maza, Jose; Rudnick, Gregory; Treister, Ezequiel

2009-01-01

We present a new, K-selected, optical-to-near infrared photometric catalog of the Extended Chandra Deep Field South (ECDFS), making it publicly available to the astronomical community. 22 Imaging and spectroscopy data and catalogs are freely available through the MUSYC Public Data Release webpage: http://www.astro.yale.edu/MUSYC/. The data set is founded on publicly available imaging, supplemented by original z'JK imaging data collected as part of the MUltiwavelength Survey by Yale-Chile (MUSYC). The final photometric catalog consists of photometry derived from UU 38 BVRIz'JK imaging covering the full 1/2 x 1/2 square circ of the ECDFS, plus H-band photometry for approximately 80% of the field. The 5σ flux limit for point sources is K (AB) tot = 22.0. This is also the nominal completeness and reliability limit of the catalog: the empirical completeness for 21.75 85%. We have verified the quality of the catalog through both internal consistency checks, and comparisons to other existing and publicly available catalogs. As well as the photometric catalog, we also present catalogs of photometric redshifts and rest-frame photometry derived from the 10-band photometry. We have collected robust spectroscopic redshift determinations from published sources for 1966 galaxies in the catalog. Based on these sources, we have achieved a (1σ) photometric redshift accuracy of Δz/(1 + z) = 0.036, with an outlier fraction of 7.8%. Most of these outliers are X-ray sources. Finally, we describe and release a utility for interpolating rest-frame photometry from observed spectral energy distributions, dubbed InterRest. 23 InterRest is available via http://www.strw.leidenuniv.nl/~ent/InterRest. Documentation and a complete walkthrough can be found at the same address.

Chandra Observations of Tycho's Supernova Remnant U. Hwang , R ...

Indian Academy of Sciences (India)

R. Narasimhan (Krishtel eMaging) 1461 1996 Oct 15 13:05:22

runaway thermal instabilities in a white dwarf. It was observed for 50 ks with the superb 0.5 resolution mirror on the Chandra X-ray .... emission that comes from ejecta that have propagated to the forward shock. Such a spectrum, taken from a portion of the west rim of the remnant, is shown in the right panel of Fig. 2. The fitted ...

Observations of the Crab Nebula with the Chandra X-Ray Observatory

Science.gov (United States)

Weisskopf, Martin C.

2012-01-01

The Crab Nebula and its pulsar has been the subject of a number of detailed observations with the Chandra X-ray Observatory. The superb angular resolution of Chandra s high-resolution telescope has made possible numerous remarkable results. Here we describe a number of specific studies of the Crab that I and my colleagues have undertaken. We discuss the geometry of the system, which indicates that the "inner X-ray ring", typically identified with the termination shock of the pulsar s particle wind, is most likely not in the equatorial plane of the pulsar. Other topics are the northern wisps and their evolution with time; the characterization of features in the jet to the southeast; pulse-phase spectroscopy and possible correlations with the features at other wavelengths, particularly the optical polarization; and a search for correlations of the X-ray flux with the recently-discovered gamma -ray flares.

Chandra Observations of Neutron Stars: An Overview

Science.gov (United States)

Weisskopf, Martin C.; Karovska, M.; Pavlov, G. G.; Zavlin, V. E.; Clarke, Tracy

2006-01-01

We present a brief review of Chandra X-ray Observatory observations of neutron stars. The outstanding spatial and spectral resolution of this great observatory have allowed for observations of unprecedented clarity and accuracy. Many of these observations have provided new insights into neutron star physics. We present an admittedly biased and overly brief overview of these observations, highlighting some new discoveries made possible by the Observatory's unique capabilities. We also include our analysis of recent multiwavelength observations of the putative pulsar and its pulsar-wind nebula in the IC 443 SNR.

Chandra Observation of Polaris: Census of Low-mass Companions

Science.gov (United States)

Evans, Nancy Remage; Guinan, Edward; Engle, Scott; Wolk, Scott J.; Schlegel, Eric; Mason, Brian D.; Karovska, Margarita; Spitzbart, Bradley

2010-05-01

We have observed Cepheid Polaris (α UMi A: F7 Ib [Aa] + F6 V [Ab]) with Chandra ACIS-I for 10 ks. An X-ray source was found at the location of Polaris with log LX = 28.89 erg s-1 (0.3-8 keV) and kT = 0.6 keV. A spectrum this soft could come from either the supergiant or the dwarf, as shown by comparable coronal stars. Two resolved low-mass visual companions, "C" and "D," are not physical members of the system based on the lack of X-rays (indicating an age older than the Cepheid) and inconsistent proper motions. Polaris B is not an X-ray source, consistent with its early F spectral type, and probably does not have a lower mass companion itself. A possible more distant member is identified, and an additional less plausible one. This provides a complete census of companions out to 0.1 pc covering a mass ratio range of an order of magnitude and a ΔV of nearly 15 mag. Based on observations made with the NASA Chandra Satellite.

SQCX X-ray Observations Of The Deep Impact Spacecraft Close Encounters With Comets 9P/Tempel 1 And 103P/Hartley 2

Science.gov (United States)

Lisse, Carey M.; Dennerl, K.; Wolk, S. J.; Christian, D. J.; Bodewits, D.; Zurbuchen, T. H.; Combi, M.

2010-03-01

We present results from the extensive Chandra, SWIFT, Spitzer, and groundbased observing campaigns studying Comet 9P/Tempel 1 in support of NASA's Deep Impact (DI) mission as an indication of the results expected for the next DI flyby of comet 103P/Hartley 2 at 0.1 AU geocentric distance in November 2010. 9P/Tempel 1 was observed for 300 ksec between 30th June and 24th July 2005, and continuously for 60 ksec on July 4th during the impact event. X-ray emission qualitatively similar to that observed for the collisionally thin, cold wind comet 2P/Encke system (Lisse et al. 2005) was found, with emission morphology centered on the nucleus and emission lines due to C, N, O, and Ne solar wind minor ions. The comet was relatively faint on July 4th, and the total increase in x-ray flux due to the Deep Impact excavation was small, 20% of the immediate pre-impact value, consistent with estimates that the total coma neutral gas release due to the impact was 5 x 106 kg ( 10 hrs of normal coma outflow). Over time, other temporally variable spectral features due to changing solar wind flux densities and charge states were clearly seen. Good agreement between the Chandra and SWIFT x-ray photometry was found. Two flares, much stronger than the man-made increase due to Deep Impact, were found in the observed x-rays on June 30th and July 8th, 2005, and are coincident with increases in the solar wind flux arriving at the comet. Modeling of the Chandra data using observed Spitzer gas production rates and ACE solar wind ion fluxes with a SWCX mechanism for the emission was found to be consistent with the temporal- and spectral behavior expected for a slow, hot wind typical of low latitude emission from the solar corona interacting with the comet's neutral coma.

The Restless Universe - Understanding X-Ray Astronomy in the Age of Chandra and Newton

Science.gov (United States)

Schlegel, Eric M.

2002-10-01

Carl Sagan once noted that there is only one generation that gets to see things for the first time. We are in the midst of such a time right now, standing on the threshold of discovery in the young and remarkable field of X-ray astronomy. In The Restless Universe , astronomer Eric Schlegel offers readers an informative survey of this cutting-edge science. Two major space observatories launched in the last few years--NASA's Chandra and the European Newton --are now orbiting the Earth, sending back a gold mine of data on the X-ray universe. Schlegel, who has worked on the Chandra project for seven years, describes the building and launching of this space-based X-ray observatory. But the book goes far beyond the story of Chandra . What Schlegel provides here is the background a nonscientist would need to grasp the present and follow the future of X-ray astronomy. He looks at the relatively brief history of the field, the hardware used to detect X-rays, the satellites--past, present, and future--that have been or will be flown to collect the data, the way astronomers interpret this data, and, perhaps most important, the insights we have already learned as well as speculations about what we may soon discover. And throughout the book, Schlegel conveys the excitement of looking at the universe from the perspective brought by these new observatories and the sharper view they deliver. Drawing on observations obtained from Chandra, Newton , and previous X-ray observatories, The Restless Universe gives a first look at an exciting field which significantly enriches our understanding of the universe.

Simultaneous Chandra and NuSTAR Observations of the Highly Obscured AGN Candidate in NGC660.

Science.gov (United States)

Annuar, Ady

2014-09-01

We are using NuSTAR to undertake a detailed investigation of the obscured AGN population at D<15Mpc. Our latest target is NGC660 where the presence of an AGN has been ambiguous. However, recently it was observed to undergo a radio outburst which reveals a bright continuum source (Argo et al. 2015), coincident with Chandra 2-8 keV emission from one of the three point sources near the nucleus (<5"). This confirms and pinpoints the X-ray position of the AGN. Comparisons of the Chandra flux with the radio emission and other multiwavelength luminosity indicators indicate that the X-ray flux is suppressed, suggesting that it is absorbed by a high column of gas. A NuSTAR observation for this object has been scheduled as part of our program. The requested Chandra observation is essential to unambiguously constrain the AGN and isolate it from other sources at <8 keV. When combined with NuSTAR, we will then be able to accurately characterise the 0.5-30 keV spectrum of the AGN for the first time.

VARIABILITY OF OPTICAL COUNTERPARTS IN THE CHANDRA GALACTIC BULGE SURVEY

Energy Technology Data Exchange (ETDEWEB)

Britt, C. T.; Hynes, R. I.; Johnson, C. B.; Baldwin, A.; Collazzi, A.; Gossen, L. [Department of Physics and Astronomy, Louisiana State University, Baton Rouge, LA 70803-4001 (United States); Jonker, P. G.; Torres, M. A. P. [SRON, Netherlands Institute for Space Research, Sorbonnelaan 2, 3584 CA Utrecht (Netherlands); Nelemans, G. [Department of Astrophysics, IMAPP, Radboud University Nijmegen, Heyendaalseweg 135, 6525 AJ, Nijmegen (Netherlands); Maccarone, T. [Department of Physics, Texas Tech University, Box 41051, Science Building, Lubbock, TX 79409-1051 (United States); Steeghs, D.; Greiss, S. [Astronomy and Astrophysics, Department of Physics, University of Warwick, Coventry, CV4 7AL (United Kingdom); Heinke, C. [Department of Physics, University of Alberta, CCIS 4-183, Edmonton, AB T6G 2E1 (Canada); Bassa, C. G. [Jodrell Bank Centre for Astrophysics, School of Physics and Astronomy, University of Manchester, Manchester M13 9PL (United Kingdom); Villar, A. [Department of Physics, Massachussettes Institute of Technology, 77 Massachusetts Avenue, Cambridge, MA 02139-4307 (United States); Gabb, M. [Department of Physics, Florida Atlantic University, 777 Glades Road, Boca Raton, FL 33431-0991 (United States)

2014-09-01

We present optical light curves of variable stars consistent with the positions of X-ray sources identified with the Chandra X-ray Observatory for the Chandra Galactic Bulge Survey (GBS). Using data from the Mosaic-II instrument on the Blanco 4 m Telescope at CTIO, we gathered time-resolved photometric data on timescales from ∼2 hr to 8 days over the 3/4 of the X-ray survey containing sources from the initial GBS catalog. Among the light curve morphologies we identify are flickering in interacting binaries, eclipsing sources, dwarf nova outbursts, ellipsoidal variations, long period variables, spotted stars, and flare stars. Eighty-seven percent of X-ray sources have at least one potential optical counterpart. Twenty-seven percent of these candidate counterparts are detectably variable; a much greater fraction than expected for randomly selected field stars, which suggests that most of these variables are real counterparts. We discuss individual sources of interest, provide variability information on candidate counterparts, and discuss the characteristics of the variable population.

Infrared Counterparts to Chandra X-Ray Sources in the Antennae

Science.gov (United States)

Clark, D. M.; Eikenberry, S. S.; Brandl, B. R.; Wilson, J. C.; Carson, J. C.; Henderson, C. P.; Hayward, T. L.; Barry, D. J.; Ptak, A. F.; Colbert, E. J. M.

2007-03-01

We use deep J (1.25 μm) and Ks (2.15 μm) images of the Antennae (NGC 4038/4039) obtained with the Wide-field InfraRed Camera on the Palomar 200 inch (5 m) telescope, together with the Chandra X-ray source list of Zezas and coworkers to search for infrared counterparts to X-ray point sources. We establish an X-ray/IR astrometric frame tie with ~0.5" rms residuals over a ~4.3' field. We find 13 ``strong'' IR counterparts brighter than Ks=17.8 mag and 99.9% confidence level that IR counterparts to X-ray sources are ΔMKs~1.2 mag more luminous than average non-X-ray clusters. We also note that the X-ray/IR matches are concentrated in the spiral arms and ``overlap'' regions of the Antennae. This implies that these X-ray sources lie in the most ``super'' of the Antennae's super star clusters, and thus trace the recent massive star formation history here. Based on the NH inferred from the X-ray sources without IR counterparts, we determine that the absence of most of the ``missing'' IR counterparts is not due to extinction, but that these sources are intrinsically less luminous in the IR, implying that they trace a different (possibly older) stellar population. We find no clear correlation between X-ray luminosity classes and IR properties of the sources, although small-number statistics hamper this analysis.

Middle Tier Services Accessing the Chandra X-Ray Center Data Archive

Science.gov (United States)

Patz, A.; Harbo, P.; Moran, J.; van Stone, D.; Zografou, P.

The Chandra Data Archive team at the Chandra X-ray Center has developed middle tier services that are used by both our search and retrieval applications to uniformly access our data repository. Accessible through an HTTP URL interface, these services can be called by our J2EE web application (WebChaser) and our Java Swing application (Chaser), as well as any other HTTP client. Programs can call the services to retrieve observation data such as a single FITS file, a proposal abstract or a detailed report of observation parameters. Having a central interface to the archive, shared by client applications, facilitates code reusability and easier maintenance. These middle tier services have been written in Java and packaged into a single J2EE application called the Search and Retrieval (SR) Services. The package consists of a web application front-end and an Enterprise Java Beans back-end. This paper describes the design and use of the SR Services.

Rapport de frais de 2016-2017 pour Chandra Madramootoo | CRDI ...

International Development Research Centre (IDRC) Digital Library (Canada)

Rapport de frais de 2016-2017 pour Chandra Madramootoo. Total des frais de déplacement : CAD$10,750.19. Réunion du Conseil des gouverneurs. 20 mars 2017 au 22 mars 2017. CAD$821.31. Réunion du Conseil des gouverneurs. 20 novembre 2016 au 23 novembre 2016. CAD$907.94. Initiation des nouveaux ...

Romanticism or Reality? An Exploration of Frances Mary Hendry's "Chandra."

Science.gov (United States)

Johnson, Jilaine

This paper singles out a novel written for children about India, "Chandra" (1995) by Frances Mary Hendry, as a powerful and useful novel to present to today's 11 to 14 year old students. The paper contends that the novel allows students to explore and consider different value systems, challenges them to become aware of prejudice and the…

Chandra Survey of Nearby Galaxies: The Catalog

Energy Technology Data Exchange (ETDEWEB)

She, Rui; Feng, Hua [Department of Engineering Physics and Center for Astrophysics, Tsinghua University, Beijing 100084 (China); Ho, Luis C. [Kavli Institute for Astronomy and Astrophysics, Peking University, Beijing 100087 (China)

2017-02-01

We searched the public archive of the Chandra X-ray Observatory as of 2016 March and assembled a sample of 719 galaxies within 50 Mpc with available Advanced CCD Imaging Spectrometer observations. By cross-correlation with the optical or near-infrared nuclei of these galaxies, 314 of them are identified to have an X-ray active galactic nucleus (AGN). The majority of them are low-luminosity AGNs and are unlikely X-ray binaries based upon their spatial distribution and luminosity functions. The AGN fraction is around 60% for elliptical galaxies and early-type spirals, but drops to roughly 20% for Sc and later types, consistent with previous findings in the optical. However, the X-ray survey is more powerful in finding weak AGNs, especially from regions with active star formation that may mask the optical AGN signature. For example, 31% of the H ii nuclei are found to harbor an X-ray AGN. For most objects, a single power-law model subject to interstellar absorption is adequate to fit the spectrum, and the typical photon index is found to be around 1.8. For galaxies with a non-detection, their stacked Chandra image shows an X-ray excess with a luminosity of a few times 10{sup 37} erg s{sup −1} on average around the nuclear region, possibly composed of faint X-ray binaries. This paper reports on the technique and results of the survey; in-depth analysis and discussion of the results will be reported in forthcoming papers.

Chandra X-ray Observations of Jovian Low-latitude Emissions: Morphological, Temporal, and Spectral Characteristics

Science.gov (United States)

Bhardwaj, Anil; Elsner, Ronald F.; Gladstone, G. Randall; Cravens, Thomas E.; Waiate J. Hunter, Jr.; Branduardi-Raymont, Graziella; Ford, Peter

2004-01-01

Chandra observed X-rays from Jupiter during 24-26 February 2003 for about 40 hours with the ACIS-S and HRC-I instruments. The analysis of Jovian low-latitude "disk" Xray emissions are presented and compared with the high-latitude "auroral" emissions. We report the first Chandra ACIS-S measured X-ray spectrum (0.3-2 keV) of Jupiter's low-latitude disk The disk X-ray emission is harder and extends to higher energies than the auroral spectrum. The temporal variation in the Jovian disk X-rays is on an average consistent with those in the solar X-rays observed by GOES, and TIMED/SSE. Contrary to the auroral X-rays, the disk emissions are uniformly distributed over Jupiter; no indication of longitudinal dependence or correlation with surface magneh field strength is visible. Also, unlike the approx. 40 +/- 20 min periodic oscillations seen in the auroral X-ray emissions, the disk emissions do not show any periodic oscillations. The disk spectrum seems to be consistent with resonant and fluorescent scattering of solar X-rays by the Jovian upper atmosphere. Jupiter's disk is found to be about 50% dimmer in soft X-rays in February 2003 compared that in December 2000, which is consistent with the decrease in solar activity. No evidence of lightning-induced X-rays is seen in the Chandra X-ray data. The Jovian disk spectra observed with Chandra-ACIS is stronger than that observed with XMM-Newton two months later during April 28-29, 2003. The XMM-Newton Xray image of Jupiter shows evidence of limb darkening on the anti-sunward side as seen from Earth, as well as an asymmetry with respect to the subsolar point: suggesting a solar driven process.

The XMM deep survey in the CDF-S. X. X-ray variability of bright sources

Science.gov (United States)

Falocco, S.; Paolillo, M.; Comastri, A.; Carrera, F. J.; Ranalli, P.; Iwasawa, K.; Georgantopoulos, I.; Vignali, C.; Gilli, R.

2017-12-01

Aims: We aim to study the variability properties of bright hard X-ray selected active galactic nuclei (AGN) in the redshift range between 0.3 and 1.6 detected in the Chandra Deep Field South (XMM-CDFS) by a long ( 3 Ms) XMM observation. Methods: Taking advantage of the good count statistics in the XMM CDFS, we search for flux and spectral variability using the hardness ratio (HR) techniques. We also investigate the spectral variability of different spectral components (photon index of the power law, column density of the local absorber, and reflection intensity). The spectra were merged in six epochs (defined as adjacent observations) and in high and low flux states to understand whether the flux transitions are accompanied by spectral changes. Results: The flux variability is significant in all the sources investigated. The HRs in general are not as variable as the fluxes, in line with previous results on deep fields. Only one source displays a variable HR, anti-correlated with the flux (source 337). The spectral analysis in the available epochs confirms the steeper when brighter trend consistent with Comptonisation models only in this source at 99% confidence level. Finding this trend in one out of seven unabsorbed sources is consistent, within the statistical limits, with the 15% of unabsorbed AGN in previous deep surveys. No significant variability in the column densities, nor in the Compton reflection component, has been detected across the epochs considered. The high and low states display in general different normalisations but consistent spectral properties. Conclusions: X-ray flux fluctuations are ubiquitous in AGN, though in some cases the data quality does not allow for their detection. In general, the significant flux variations are not associated with spectral variability: photon index and column densities are not significantly variable in nine out of the ten AGN over long timescales (from three to six and a half years). Photon index variability is

Role of the Chandra X-Ray Observatory Observations for the Study of Ionized Plasmas

Science.gov (United States)

Weisskopf, Martin C.

2010-01-01

The Chandra X-Ray Observatory, launched in 1999, is now beginning its 12-th year of operation. Chandra, the X-ray component of NASA s Great Observatory program, continues to operate efficiently, somewhat remarkable considering that the Observatory was designed for three years of operation with a goal of five. The Observatory features X-ray optics with sub-arcsecond angular resolution and a small suite of instruments, including transmission gratings, which allow for high-resolution spectroscopy of point sources. We will detail the capabilities of the Observatory for making such spectroscopic measurements and discuss a number of examples of what has been learned about the astrophysical plasmas capable of producing bright X-ray emission.

The kinematics and chemical stratification of the type Ia supernova remnant 0519-69.0 : an XMM-Newton and Chandra study

NARCIS (Netherlands)

Kosenko, D.; Helder, E.A.; Vink, J.

2010-01-01

We present a detailed analysis of the XMM-Newton and Chandra X-ray data of the young type Ia supernova remnant SNR 0519-69.0, which is situated in the Large Magellanic Cloud. We used data from both the Chandra ACIS and XMM-Newton EPIC MOS instruments, and high resolution X-ray spectra obtained with

DeepAnomaly: Combining Background Subtraction and Deep Learning for Detecting Obstacles and Anomalies in an Agricultural Field

Directory of Open Access Journals (Sweden)

Peter Christiansen

2016-11-01

Full Text Available Convolutional neural network (CNN-based systems are increasingly used in autonomous vehicles for detecting obstacles. CNN-based object detection and per-pixel classification (semantic segmentation algorithms are trained for detecting and classifying a predefined set of object types. These algorithms have difficulties in detecting distant and heavily occluded objects and are, by definition, not capable of detecting unknown object types or unusual scenarios. The visual characteristics of an agriculture field is homogeneous, and obstacles, like people, animals and other obstacles, occur rarely and are of distinct appearance compared to the field. This paper introduces DeepAnomaly, an algorithm combining deep learning and anomaly detection to exploit the homogenous characteristics of a field to perform anomaly detection. We demonstrate DeepAnomaly as a fast state-of-the-art detector for obstacles that are distant, heavily occluded and unknown. DeepAnomaly is compared to state-of-the-art obstacle detectors including “Faster R-CNN: Towards Real-Time Object Detection with Region Proposal Networks” (RCNN. In a human detector test case, we demonstrate that DeepAnomaly detects humans at longer ranges (45–90 m than RCNN. RCNN has a similar performance at a short range (0–30 m. However, DeepAnomaly has much fewer model parameters and (182 ms/25 ms = a 7.28-times faster processing time per image. Unlike most CNN-based methods, the high accuracy, the low computation time and the low memory footprint make it suitable for a real-time system running on a embedded GPU (Graphics Processing Unit.

Early Chandra X-ray Observations of Eta Carinae

OpenAIRE

Seward, F. D.; Butt, Y. M.; Karovska, M.; Schlegel, A. Prestwich. E. M.; Corcoran, M.

2001-01-01

Sub-arcsecond resolution Chandra observations of Eta Carinae reveal a 40 arcsec X 70 arcsec ring or partial shell of X-ray emission surrounding an unresolved, bright, central source. The spectrum of the central source is strongly absorbed and can be fit with a high-temperature thermal continuum and emission lines. The surrounding shell is well outside the optical/IR bipolar nebula and is coincident with the Outer Shell of Eta Carinae. The X-ray spectrum of the Shell is much softer than that o...

Sensitivity of GC-EI/MS, GC-EI/MS/MS, LC-ESI/MS/MS, LC-Ag(+) CIS/MS/MS, and GC-ESI/MS/MS for analysis of anabolic steroids in doping control.

Science.gov (United States)

Cha, Eunju; Kim, Sohee; Kim, Ho Jun; Lee, Kang Mi; Kim, Ki Hun; Kwon, Oh-Seung; Lee, Jaeick

2015-01-01

This study compared the sensitivity of various separation and ionization methods, including gas chromatography with an electron ionization source (GC-EI), liquid chromatography with an electrospray ionization source (LC-ESI), and liquid chromatography with a silver ion coordination ion spray source (LC-Ag(+) CIS), coupled to a mass spectrometer (MS) for steroid analysis. Chromatographic conditions, mass spectrometric transitions, and ion source parameters were optimized. The majority of steroids in GC-EI/MS/MS and LC-Ag(+) CIS/MS/MS analysis showed higher sensitivities than those obtained with other analytical methods. The limits of detection (LODs) of 65 steroids by GC-EI/MS/MS, 68 steroids by LC-Ag(+) CIS/MS/MS, 56 steroids by GC-EI/MS, 54 steroids by LC-ESI/MS/MS, and 27 steroids by GC-ESI/MS/MS were below cut-off value of 2.0 ng/mL. LODs of steroids that formed protonated ions in LC-ESI/MS/MS analysis were all lower than the cut-off value. Several steroids such as unconjugated C3-hydroxyl with C17-hydroxyl structure showed higher sensitivities in GC-EI/MS/MS analysis relative to those obtained using the LC-based methods. The steroids containing 4, 9, 11-triene structures showed relatively poor sensitivities in GC-EI/MS and GC-ESI/MS/MS analysis. The results of this study provide information that may be useful for selecting suitable analytical methods for confirmatory analysis of steroids. Copyright © 2015 John Wiley & Sons, Ltd.

Staging of cortical and deep grey matter functional connectivity changes in multiple sclerosis.

Science.gov (United States)

Meijer, Kim A; Eijlers, Anand J C; Geurts, Jeroen J G; Schoonheim, Menno M

2018-02-01

Functional connectivity is known to increase as well as decrease throughout the brain in multiple sclerosis (MS), which could represent different stages of the disease. In addition, functional connectivity changes could follow the atrophy pattern observed with disease progression, that is, moving from the deep grey matter towards the cortex. This study investigated when and where connectivity changes develop and explored their clinical and cognitive relevance across different MS stages. A cohort of 121 patients with early relapsing-remitting MS (RRMS), 122 with late RRMS and 53 with secondary progressive MS (SPMS) as well as 96 healthy controls underwent MRI and neuropsychological testing. Functional connectivity changes were investigated for (1) within deep grey matter connectivity, (2) connectivity between the deep grey matter and cortex and (3) within-cortex connectivity. A post hoc regional analysis was performed to identify which regions were driving the connectivity changes. Patients with late RRMS and SPMS showed increased connectivity of the deep grey matter, especially of the putamen and palladium, with other deep grey matter structures and with the cortex. Within-cortex connectivity was decreased, especially for temporal, occipital and frontal regions, but only in SPMS relative to early RRMS. Deep grey matter connectivity alterations were related to cognition and disability, whereas within-cortex connectivity was only related to disability. Increased connectivity of the deep grey matter became apparent in late RRMS and further increased in SPMS. The additive effect of cortical network degeneration, which was only seen in SPMS, may explain the sudden clinical deterioration characteristic to this phase of the disease. © Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2018. All rights reserved. No commercial use is permitted unless otherwise expressly granted.

The Chandra Source Catalog 2.0: Estimating Source Fluxes

Science.gov (United States)

Primini, Francis Anthony; Allen, Christopher E.; Miller, Joseph; Anderson, Craig S.; Budynkiewicz, Jamie A.; Burke, Douglas; Chen, Judy C.; Civano, Francesca Maria; D'Abrusco, Raffaele; Doe, Stephen M.; Evans, Ian N.; Evans, Janet D.; Fabbiano, Giuseppina; Gibbs, Danny G., II; Glotfelty, Kenny J.; Graessle, Dale E.; Grier, John D.; Hain, Roger; Hall, Diane M.; Harbo, Peter N.; Houck, John C.; Lauer, Jennifer L.; Laurino, Omar; Lee, Nicholas P.; Martínez-Galarza, Juan Rafael; McCollough, Michael L.; McDowell, Jonathan C.; McLaughlin, Warren; Morgan, Douglas L.; Mossman, Amy E.; Nguyen, Dan T.; Nichols, Joy S.; Nowak, Michael A.; Paxson, Charles; Plummer, David A.; Rots, Arnold H.; Siemiginowska, Aneta; Sundheim, Beth A.; Tibbetts, Michael; Van Stone, David W.; Zografou, Panagoula

2018-01-01

The Second Chandra Source Catalog (CSC2.0) will provide information on approximately 316,000 point or compact extended x-ray sources, derived from over 10,000 ACIS and HRC-I imaging observations available in the public archive at the end of 2014. As in the previous catalog release (CSC1.1), fluxes for these sources will be determined separately from source detection, using a Bayesian formalism that accounts for background, spatial resolution effects, and contamination from nearby sources. However, the CSC2.0 procedure differs from that used in CSC1.1 in three important aspects. First, for sources in crowded regions in which photometric apertures overlap, fluxes are determined jointly, using an extension of the CSC1.1 algorithm, as discussed in Primini & Kashyap (2014ApJ...796…24P). Second, an MCMC procedure is used to estimate marginalized posterior probability distributions for source fluxes. Finally, for sources observed in multiple observations, a Bayesian Blocks algorithm (Scargle, et al. 2013ApJ...764..167S) is used to group observations into blocks of constant source flux.In this poster we present details of the CSC2.0 photometry algorithms and illustrate their performance in actual CSC2.0 datasets.This work has been supported by NASA under contract NAS 8-03060 to the Smithsonian Astrophysical Observatory for operation of the Chandra X-ray Center.

A deep NuSTAR observation of M51: Investigating its Compton-thick nucleus, LINER companion and ULXs above 10 keV

Science.gov (United States)

Brightman, Murray; Annuar, Ady; Alexander, David M.; Earnshaw, Hannah; Gandhi, Poshak; Hornschemeier, Ann E.; Lehmer, Bret; Ptak, Andrew; Rangelov, Blagoy; Roberts, Tim P.; Stern, Daniel; Zezas, Andreas

2017-08-01

We present the results from a deep 200ks observation of M51 with NuSTAR. This observation was taken simultaneously with Chandra to provide soft-X-ray-coverage as well as to resolve the different point sources. We detect the Compton-thick nucleus of M51a, the LINER nucleus of M51b and several ultraluminous X-ray sources located in the galaxies above 10 keV. From X-ray torus modeling, we find that the covering factor of the torus in the nucleus of M51a is ~40% and supports a decline in the obscured fration at low X-ray luminosities. We find that the X-ray spectrum of the intermediate mass black hole candidate, ULX-7, is consistent with a power-law up to high energies, supporting its IMBH status. We further resolve the nucleus of M51b into two X-ray sources with Chandra, and measure its X-ray luminosity.

Dissecting Photometric Redshift for Active Galactic Nucleus Using XMM- and Chandra-COSMOS Samples

NARCIS (Netherlands)

Salvato, M.; Ilbert, O.; Hasinger, G.; Rau, A.; Civano, F.; Zamorani, G.; Brusa, M.; Elvis, M.; Vignali, C.; Aussel, H.; Comastri, A.; Fiore, F.; Le Floc'h, E.; Mainieri, V.; Bardelli, S.; Bolzonella, M.; Bongiorno, A.; Capak, P.; Caputi, K.; Cappelluti, N.; Carollo, C. M.; Contini, T.; Garilli, B.; Iovino, A.; Fotopoulou, S.; Fruscione, A.; Gilli, R.; Halliday, C.; Kneib, J. -P.; Kakazu, Y.; Kartaltepe, J. S.; Koekemoer, A. M.; Kovac, K.; Ideue, Y.; Ikeda, H.; Impey, C. D.; Le Fevre, O.; Lamareille, F.; Lanzuisi, G.; Le Borgne, J. -F.; Le Brun, V.; Lilly, S.; Maier, C.; Manohar, S.; Masters, D.; McCracken, H.; Messias, H.; Mignoli, M.; Mobasher, B.; Nagao, T.; Pello, R.; Puccetti, S.; Perez-Montero, E.; Renzini, A.; Sargent, M.; Sanders, D. B.; Scodeggio, M.; Scoville, N.; Shopbell, P.; Silvermann, J.; Taniguchi, Y.; Tasca, L.; Tresse, L.; Trump, J. R.; Zucca, E.

2011-01-01

In this paper, we release accurate photometric redshifts for 1692 counterparts to Chandra sources in the central square degree of the Cosmic Evolution Survey (COSMOS) field. The availability of a large training set of spectroscopic redshifts that extends to faint magnitudes enabled photometric

CHANDRA CLUSTER COSMOLOGY PROJECT III: COSMOLOGICAL PARAMETER CONSTRAINTS

International Nuclear Information System (INIS)

Vikhlinin, A.; Forman, W. R.; Jones, C.; Murray, S. S.; Kravtsov, A. V.; Burenin, R. A.; Voevodkin, A.; Ebeling, H.; Hornstrup, A.; Nagai, D.; Quintana, H.

2009-01-01

Chandra observations of large samples of galaxy clusters detected in X-rays by ROSAT provide a new, robust determination of the cluster mass functions at low and high redshifts. Statistical and systematic errors are now sufficiently small, and the redshift leverage sufficiently large for the mass function evolution to be used as a useful growth of a structure-based dark energy probe. In this paper, we present cosmological parameter constraints obtained from Chandra observations of 37 clusters with (z) = 0.55 derived from 400 deg 2 ROSAT serendipitous survey and 49 brightest z ∼ 0.05 clusters detected in the All-Sky Survey. Evolution of the mass function between these redshifts requires Ω Λ > 0 with a ∼5σ significance, and constrains the dark energy equation-of-state parameter to w 0 = -1.14 ± 0.21, assuming a constant w and a flat universe. Cluster information also significantly improves constraints when combined with other methods. Fitting our cluster data jointly with the latest supernovae, Wilkinson Microwave Anisotropy Probe, and baryonic acoustic oscillation measurements, we obtain w 0 = -0.991 ± 0.045 (stat) ±0.039 (sys), a factor of 1.5 reduction in statistical uncertainties, and nearly a factor of 2 improvement in systematics compared with constraints that can be obtained without clusters. The joint analysis of these four data sets puts a conservative upper limit on the masses of light neutrinos Σm ν M h and σ 8 from the low-redshift cluster mass function.

Chandra X-ray Data Analysis in Educational Environments

Science.gov (United States)

Matilsky, T.; Etkina, E.; Lestition, K.; Mandel, E.; Joye, W.

2004-12-01

Recent progress in both software and remote connectivity capabilities have made it possible for authentic data analysis tasks to be presented in a wide range of educational venues. No longer are precollege teachers and students, and interested members of the public limited by their lack of access to the scientific workstations and UNIX-based imaging and analytical software used by the research community. Through a suite of programs that couples a simplified graphical user interface using the "DS9" imaging software with a "virtual observatory" capability that processes the analytical algorithms used by X-ray astronomers, we can access archived Chandra observations and generate images, as well as light curves, energy spectra, power spectra and other common examples of science tasks. The system connects to a remote UNIX server, but the user may be sited on a PC or Mac platform. Furthermore, the use of VNC (a remote desktop display environment) allows a teacher to view, comment on and debug any analysis task in real time, from anywhere in the world, and across any computer platform. This makes these programs especially useful in distance learning settings. We have developed, tested and used these capabilities in a wide variety of educational arenas, from 4 week intensive courses in X-ray astronomy research techniques for precollege students and teachers, to one day teacher enrichment workshops, to modules of classroom activities suitable for precollege grade levels, using a variety of cosmic X-ray sources. Examples using archived Chandra observations will be presented demonstrating the flexibility and usefulness of these resources.

Determination of trace elements in seawater by air-flow injection/ICP-MS with chelating resin preconcentration

International Nuclear Information System (INIS)

Lee, Kyue-Hyung; Ohshima, Mitsuko; Motomizu, Shoji

2002-01-01

Multielement determination of major to trace metals in a deep seawater malt was accomplished by inductively coupled plasma-mass spectrometry (ICP-MS) together with inductively coupled plasma-atomic emission spectrometry (ICP-AES). Major elements, such as Na, K, Mg, and Ca, were measured by ICP-AES and normal continuos nebulization ICP-MS after sample dilution by 10 3 -10 6 fold. Fifteen trace elements in the concentrated metal solutions pretreated with cation-exchange resin or chelating resin could be simultaneously determined by air-flow injection/ICP-mass spectrometry (AFI/ICP-MS). Since the injection volume for AFI/ICP-MS was 25 μl, final samples volumes less than 500 μl were enough for several replicate measurements. Three different preconcentration methods assisted with AFI/ICP-MS were examined and could be successfully applied to a deep seawater malt. The analytical results of rate earth elements (REEs) and Co, Ni, Cu, Zn, Cd, and Pb obtained by AFI/ICP-MS coupled with disk filtration method using iminodiacetate (IDA)-type chelating resin were favorably agreed with the data obtained by AFI/ICP-MS coupled with column preconcentration method using chitosan-based chelating resin. (author)

A LABOCA SURVEY OF THE EXTENDED CHANDRA DEEP FIELD SOUTH-SUBMILLIMETER PROPERTIES OF NEAR-INFRARED SELECTED GALAXIES

International Nuclear Information System (INIS)

Greve, T. R.; Walter, F.; Bell, E. F.; Dannerbauer, H.; Rix, H.-W.; Schinnerer, E.; Weiss, A.; Kovacs, A.; Smail, I.; Coppin, K. E. K.; Alexander, D.; Zheng, X. Z.; Knudsen, K. K.; Bertoldi, F.; De Breuck, C.; Dickinson, M.; Gawiser, E.; Lutz, D.; Brandt, N.; Chapman, S. C.

2010-01-01

Using the 330 hr ESO-MPG 870 μm survey of the Extended Chandra Deep Field South (ECDF-S) obtained with the Large Apex BOlometer CAmera (LABOCA) on the Atacama Pathfinder EXperiment (APEX), we have carried out a stacking analysis at submillimeter (submm) wavelengths of a sample of 8266 near-infra-red (near-IR) selected (K vega ≤ 20) galaxies, including 893 BzK galaxies, 1253 extremely red objects (EROs), and 737 distant red galaxies (DRGs), selected from the Multi-wavelength Survey by Yale-Chile (MUSYC). We measure average 870 μm fluxes of 0.22 ± 0.01 mJy (22.0σ), 0.48 ± 0.04 mJy (12.0σ), 0.39 ± 0.03 mJy (13.0σ), and 0.43 ± 0.04 mJy (10.8σ) for the K vega ≤ 20, BzK, ERO, and DRG samples, respectively. For the BzK, ERO, and DRG sub-samples, which overlap to some degree and are likely to be at z ≅ 1-2, this implies an average far-IR luminosity of ∼(1-5) x 10 11 L sun and star formation rate (SFR) of ∼20-90 M sun . Splitting the BzK galaxies into star-forming (sBzK) and passive (pBzK) galaxies, the former is significantly detected (0.50 ± 0.04 mJy, 12.5σ) while the latter is only marginally detected (0.34 ± 0.10 mJy, 3.4σ), thus confirming that the sBzK and pBzK criteria to some extent select obscured, star-forming, and truly passive galaxies, respectively. The K vega ≤ 20 galaxies are found to contribute 7.27 ± 0.34 Jy deg -2 (16.5% ± 5.7%) to the 870 μm extragalactic background light (EBL). sBzK and pBzK galaxies contribute 1.49 ± 0.22 Jy deg -2 (3.4% ± 1.3%) and 0.20 ± 0.14 Jy deg -2 (0.5% ± 0.3%) to the EBL. We present the first delineation of the average submm signal from the K vega ≤ 20 selected galaxies and their contribution to the submm EBL as a function of (photometric) redshift, and find a decline in the average submm signal (and therefore IR luminosity and SFR) by a factor ∼2-3 from z ∼ 2 to z ∼ 0. This is in line with a cosmic star formation history in which the star formation activity in galaxies increases

The software development process at the Chandra X-ray Center

Science.gov (United States)

Evans, Janet D.; Evans, Ian N.; Fabbiano, Giuseppina

2008-08-01

Software development for the Chandra X-ray Center Data System began in the mid 1990's, and the waterfall model of development was mandated by our documents. Although we initially tried this approach, we found that a process with elements of the spiral model worked better in our science-based environment. High-level science requirements are usually established by scientists, and provided to the software development group. We follow with review and refinement of those requirements prior to the design phase. Design reviews are conducted for substantial projects within the development team, and include scientists whenever appropriate. Development follows agreed upon schedules that include several internal releases of the task before completion. Feedback from science testing early in the process helps to identify and resolve misunderstandings present in the detailed requirements, and allows review of intangible requirements. The development process includes specific testing of requirements, developer and user documentation, and support after deployment to operations or to users. We discuss the process we follow at the Chandra X-ray Center (CXC) to develop software and support operations. We review the role of the science and development staff from conception to release of software, and some lessons learned from managing CXC software development for over a decade.

Monitoring of CH Cyg requested for Chandra and HST observations

Science.gov (United States)

Waagen, Elizabeth O.

2012-03-01

Dr. Margarita Karovska, Harvard-Smithsonian Center for Astrophysics, has requested visual and photometric observations of the symbiotic variable CH Cyg in preparation for and support of Chandra and HST observations scheduled for later in March 2012. Dr. Karovska's observations will be a followup investigation of the central region of CH Cyg and its jet that was discovered a couple of years ago. AAVSO observations are requested in order to monitor the state of the system and correlate with the satellite observations. Visual observations and CCD/PEP observations in all bands - U through J and H - are requested. Daily observations now through April 2012 and high-speed photometry through March would be appreciated. CH Cyg is currently at visual magnitude 7.7. Halpha, OIII region, and optical spectroscopy are also requested. More details on the exact dates and times of the satellite observations will be announced when they become available, but daily monitoring should begin now. [HST observations scheduled for 2012 March 18; Chandra delayed some days due to X-class solar flare of 2012 March 7.] Coordinates: RA 19 24 33.07 Dec. +50 14 29.1 (J2000.0). Finder charts may be created and data from the AAVSO International Database may be viewed, plotted, or downloaded (www.aavso.org).

CHANDRA OBSERVATION OF THE RELATIVISTIC BINARY J1906+0746

International Nuclear Information System (INIS)

Kargaltsev, O.; Pavlov, G. G.

2009-01-01

PSR J1906+0746 is a young radio pulsar (τ = 112 kyr, P = 144 ms) in a tight binary (P orb = 3.98 hr) with a compact high-mass companion (M comp ≅ 1.36 M sun ), at the distance of about 5 kpc. We observed this unique relativistic binary with the Chandra Advanced CCD Imaging Spectrometer detector for 31.6 ks. Surprisingly, not a single photon was detected within the 3'' radius from the J1906+0746 radio position. For a plausible range of hydrogen column densities, n H = (0.5-1) x 10 22 cm -2 , the nondetection corresponds to the 90% upper limit of (3-5) x 10 30 erg s -1 on the unabsorbed 0.5-8 keV luminosity for the power-law model with Γ = 1.0-2.0, and ∼10 32 erg s -1 on the bolometric luminosity of the thermal emission from the neutrons star surface. The inferred limits are the lowest known for pulsars with spin-down properties similar to those of PSR J1906+0746. We have also tentatively detected a puzzling extended structure which looks like a tilted ring with a radius of 1.'6 centered on the pulsar. The measured 0.5-8 keV flux of the feature, ∼3.1 x 10 -14 erg cm -2 s -1 , implies an unabsorbed luminosity of 1.2 x 10 32 erg s -1 (4.5 x 10 -4 of the pulsar's E-dot) for n H = 0.7 x 10 22 cm -2 . If the ring is not a peculiar noise artifact, the pulsar wind nebula around an unusually underluminous pulsar would be the most plausible interpretation.

Initial Performance of the Aspect System on the Chandra Observatory: Post-Facto Aspect Reconstruction

Science.gov (United States)

Aldcroft, T.; Karovska, M.; Cresitello-Dittmar, M.; Cameron, R.

2000-01-01

The aspect system of the Chandra Observatory plays a key role in realizing the full potential of Chandra's x-ray optics and detectors. To achieve the highest spatial and spectral resolution (for grating observations), an accurate post-facto time history of the spacecraft attitude and internal alignment is needed. The CXC has developed a suite of tools which process sensor data from the aspect camera assembly and gyroscopes, and produce the spacecraft aspect solution. In this poster, the design of the aspect pipeline software is briefly described, followed by details of aspect system performance during the first eight months of flight. The two key metrics of aspect performance are: image reconstruction accuracy, which measures the x-ray image blurring introduced by aspect; and celestial location, which is the accuracy of detected source positions in absolute sky coordinates.

A High Definition View of AGN Feedback: Chandra Imaging of Nearby Seyfert Galaxies

Science.gov (United States)

Wang, Junfeng; Fabbiano, G.; Risaliti, G.; Elvis, M.; Karovska, M.; Zezas, A.; Mundell, C. G.

2010-03-01

To improve the physics of AGN feedback, it is crucial to evaluate the true role of outflows on galaxy evolution observationally. I will present new results from Chandra spectral imaging of nearby Seyfert galaxies, which offer unique opportunities to examine feedback in action in much greater detail than at high redshift. Exploiting Chandra's highest possible resolution, we are able to study structures in NGC 4151 on spatial scales of 0.5 arcsec (30 pc), showing an extended X-ray morphology overall consistent with the optical NLR. We find that most of the NLR clouds in NGC 4151 have [OIII] to soft X-ray ratio consistent with the values observed in NLRs of some Seyfert 2 galaxies, which indicates a uniform ionization parameter even at large radii. We examine various X-ray emission mechanisms of the radio jet and consider thermal emission from interaction between radio outflow and the NLR clouds the most probable origin for the X-ray emission associated with the jet.

The Chandra Source Catalog 2.0: Combining Data for Processing (or How I learned 17 different words for "group")

Science.gov (United States)

Hain, Roger; Allen, Christopher E.; Anderson, Craig S.; Budynkiewicz, Jamie A.; Burke, Douglas; Chen, Judy C.; Civano, Francesca Maria; D'Abrusco, Raffaele; Doe, Stephen M.; Evans, Ian N.; Evans, Janet D.; Fabbiano, Giuseppina; Gibbs, Danny G., II; Glotfelty, Kenny J.; Graessle, Dale E.; Grier, John D.; Hall, Diane M.; Harbo, Peter N.; Houck, John C.; Lauer, Jennifer L.; Laurino, Omar; Lee, Nicholas P.; Martínez-Galarza, Juan Rafael; McCollough, Michael L.; McDowell, Jonathan C.; Miller, Joseph; McLaughlin, Warren; Morgan, Douglas L.; Mossman, Amy E.; Nguyen, Dan T.; Nichols, Joy S.; Nowak, Michael A.; Paxson, Charles; Plummer, David A.; Primini, Francis Anthony; Rots, Arnold H.; Siemiginowska, Aneta; Sundheim, Beth A.; Tibbetts, Michael; Van Stone, David W.; Zografou, Panagoula

2018-01-01

The Second Chandra Source Catalog (CSC2.0) combines data at multiple stages to improve detection efficiency, enhance source region identification, and match observations of the same celestial source taken with significantly different point spread functions on Chandra's detectors. The need to group data for different reasons at different times in processing results in a hierarchy of groups to which individual sources belong. Source data are initially identified as belonging to each Chandra observation ID and number (an "obsid"). Data from each obsid whose pointings are within sixty arcseconds of each other are reprojected to the same aspect reference coordinates and grouped into stacks. Detection is performed on all data in the same stack, and individual sources are identified. Finer source position and region data are determined by further processing sources whose photons may be commingled together, grouping such sources into bundles. Individual stacks which overlap to any extent are grouped into ensembles, and all stacks in the same ensemble are later processed together to identify master sources and determine their properties.We discuss the basis for the various methods of combining data for processing and precisely define how the groups are determined. We also investigate some of the issues related to grouping data and discuss what options exist and how groups have evolved from prior releases.This work has been supported by NASA under contract NAS 8-03060 to the Smithsonian Astrophysical Observatory for operation of the Chandra X-ray Center.

Normal Spiral Galaxies Really Do Have Hot Gas in Their Halos: Chandra Observations of NGC 4013 and NGC 4217.

Science.gov (United States)

Strickland, D. K.; Colbert, E. J. M.; Heckman, T. M.; Hoopes, C. G.; Howk, J. C.; Rand, R. J.

2004-08-01

Although soft X-ray emission from million degree plasma has long been observed in the halos of starburst galaxies known to have supernova-driven galactic superwinds, X-ray observations have generally failed to detect hot halos around normal spiral galaxies. Indeed, the Milky Way and NGC 891 have historically been the only genuinely "normal" spiral galaxies with unambiguous X-ray halo detections, until now. Here we report on deep observations of NGC 4013 and NGC 4217, two Milky-Way-mass spiral galaxies with star formation rates per unit area similar to the Milky Way and NGC 891, using the Chandra X-ray observatory. Preliminary investigation of the observations clearly show extra-planar diffuse X-ray emission extending several kpc into the halo of NGC 4013. We will present the results of these observations, compare them to the non-detections of hot gas around normal spirals, and relate them to galactic fountain and IGM accretion based models for hot halos. DKS acknowledges funding from NASA through the Smithsonian Astrophysical Observatory. grant G045095X.

A CHANDRA STUDY OF TEMPERATURE DISTRIBUTIONS OF THE INTRACLUSTER MEDIUM IN 50 GALAXY CLUSTERS

Energy Technology Data Exchange (ETDEWEB)

Zhu, Zhenghao; Xu, Haiguang; Li, Weitian; Hu, Dan; Zhang, Chenhao; Liu, Chengze [Department of Physics and Astronomy, Shanghai Jiao Tong University, 800 Dongchuan Road, Minhang, Shanghai 200240 (China); Wang, Jingying; Gu, Junhua; Wu, Xiang-Ping [National Astronomical Observatories, Chinese Academy of Sciences, 20A Datun Road, Beijing 100012 (China); Gu, Liyi [SRON Netherlands Institute for Space Research, Sorbonnelaan 2, 3584 CA Utrecht (Netherlands); An, Tao [Shanghai Astronomical Observatory, Chinese Academy of Sciences, 80 Nandan Road, Shanghai 200030 (China); Zhang, Zhongli [Max Planck Institute for Astrophysics, Karl-Schwarzschild-Str. 1, Postfach 1317, D-85741 Garching (Germany); Zhu, Jie, E-mail: clsn@sjtu.edu.cn, E-mail: hgxu@sjtu.edu.cn [Department of Electronic Engineering, Shanghai Jiao Tong University, 800 Dongchuan Road, Minhang, Shanghai 200240 (China)

2016-01-10

To investigate the spatial distribution of the intracluster medium temperature in galaxy clusters in a quantitative way and probe the physics behind it, we analyze the X-ray spectra from a sample of 50 clusters that were observed with the Chandra ACIS instrument over the past 15 years and measure the radial temperature profiles out to 0.45r{sub 500}. We construct a physical model that takes into consideration the effects of gravitational heating, thermal history (such as radiative cooling, active galactic nucleus feedback, and thermal conduction), and work done via gas compression, and use it to fit the observed temperature profiles by running Bayesian regressions. The results show that in all cases our model provides an acceptable fit at the 68% confidence level. For further validation, we select nine clusters that have been observed with both Chandra (out to ≳0.3r{sub 500}) and Suzaku (out to ≳1.5r{sub 500}) and fit their Chandra spectra with our model. We then compare the extrapolation of the best fits with the Suzaku measurements and find that the model profiles agree with the Suzaku results very well in seven clusters. In the remaining two clusters the difference between the model and the observation is possibly caused by local thermal substructures. Our study also implies that for most of the clusters the assumption of hydrostatic equilibrium is safe out to at least 0.5r{sub 500} and the non-gravitational interactions between dark matter and its luminous counterparts is consistent with zero.

Chandra Phase-resolved Spectroscopy of the High Magnetic Field Pulsar B1509−58

Energy Technology Data Exchange (ETDEWEB)

Hu, Chin-Ping; Ng, C.-Y. [Department of Physics, The University of Hong Kong, Pokfulam Road (Hong Kong); Takata, J. [School of Physics, Huazhong University of Science and Technology, Wuhan, Hubei (China); Shannon, R. M. [International Centre for Radio Astronomy Research, Curtin University, Bentley, WA 6102 (Australia); Johnston, S., E-mail: cphu@hku.hk, E-mail: ncy@bohr.physics.hku.hk [CSIRO Astronomy and Space Science, Australia Telescope National Facility, Box 76, Epping, NSW 1710 (Australia)

2017-04-01

We report on a timing and spectral analysis of the young, high magnetic field rotation-powered pulsar (RPP) B1509−58 using Chandra continuous-clocking mode observation. The pulsar’s X-ray light curve can be fit by the two Gaussian components and the pulsed fraction shows moderate energy dependence over the Chandra band. The pulsed X-ray spectrum is well described by a power law with a photon index 1.16(4), which is harder than the values measured with RXTE /PCA and NuSTAR . This result supports the log-parabolic model for the broadband X-ray spectrum. With the unprecedented angular resolution of Chandra , we clearly identified off-pulse X-ray emission from the pulsar, and its spectrum is best fit by a power law plus blackbody model. The latter component has a temperature of ∼0.14 keV with a bolometric luminosity comparable to the luminosities of other young and high magnetic field RPPs, and it lies between the temperature of magnetars and typical RPPs. In addition, we found that the nonthermal X-ray emission of PSR B1509−58 is significantly softer in the off-pulse phase than in the pulsed phase, with the photon index varying between 1.0 and 1.8 and anticorrelated with the flux. This is similar to the behavior of three other young pulsars. We interpreted it as different contributions of pair-creation processes at different altitudes from the neutron star surface according to the outer-gap model.

Chandra Discovers the X-ray Signature of a Powerful Wind from a Galactic Microquasar

Science.gov (United States)

2000-11-01

NASA's Chandra X-ray Observatory has detected, for the first time in X rays, a stellar fingerprint known as a P Cygni profile--the distinctive spectral signature of a powerful wind produced by an object in space. The discovery reveals a 4.5-million-mile-per-hour wind coming from a highly compact pair of stars in our galaxy, report researchers from Penn State and the Massachusetts Institute of Technology in a paper they will present on 8 November 2000 during a meeting of the High-Energy Astrophysics Division of the American Astronomical Society in Honolulu, Hawaii. The paper also has been accepted for publication in The Astrophysical Journal Letters. "To our knowledge, these are the first P Cygni profiles reported in X rays," say researchers Niel Brandt, assistant professor of astronomy and astrophysics at Penn State, and Norbert S. Schulz, research scientist at the Massachusetts Institute of Technology. The team made the discovery during their first observation of a binary-star system with the Chandra X-ray Observatory, which was launched into space in July 1999. The system, known as Circinus X-1, is located about 20,000 light years from Earth in the constellation Circinus near the Southern Cross. It contains a super-dense neutron star in orbit around a normal fusion-burning star like our Sun. Although Circinus X-1 was discovered in 1971, many properties of this system remain mysterious because Circinus X-1 lies in the galactic plane where obscuring dust and gas have blocked its effective study in many wavelengths. The P Cygni spectral profile, previously detected primarily at ultraviolet and optical wavelengths but never before in X rays, is the textbook tool astronomers rely on for probing stellar winds. The profile looks like the outline of a roller coaster, with one really big hill and valley in the middle, on a data plot with velocity on one axis and the flow rate of photons per second on the other. It is named after the famous star P Cygni, in which such

The Chandra Source Catalog: Statistical Characterization

Science.gov (United States)

Primini, Francis A.; Nowak, M. A.; Houck, J. C.; Davis, J. E.; Glotfelty, K. J.; Karovska, M.; Anderson, C. S.; Bonaventura, N. R.; Chen, J. C.; Doe, S. M.; Evans, I. N.; Evans, J. D.; Fabbiano, G.; Galle, E. C.; Gibbs, D. G., II; Grier, J. D.; Hain, R.; Hall, D. M.; Harbo, P. N.; He, X.; Lauer, J.; McCollough, M. L.; McDowell, J. C.; Miller, J. B.; Mitschang, A. W.; Morgan, D. L.; Nichols, J. S.; Plummer, D. A.; Refsdal, B. L.; Rots, A. H.; Siemiginowska, A. L.; Sundheim, B. A.; Tibbetts, M. S.; van Stone, D. W.; Winkelman, S. L.; Zografou, P.

2009-09-01

The Chandra Source Catalog (CSC) will ultimately contain more than ˜250000 x-ray sources in a total area of ˜1% of the entire sky, using data from ˜10000 separate ACIS and HRC observations of a multitude of different types of x-ray sources (see Evans et al. this conference). In order to maximize the scientific benefit of such a large, heterogeneous dataset, careful characterization of the statistical properties of the catalog, i.e., completeness, sensitivity, false source rate, and accuracy of source properties, is required. Our Characterization efforts include both extensive simulations of blank-sky and point source datasets, and detailed comparisons of CSC results with those of other x-ray and optical catalogs. We present here a summary of our characterization results for CSC Release 1 and preliminary plans for future releases. This work is supported by NASA contract NAS8-03060 (CXC).

A Deep X-ray Search for the Putative IMBH in Omega Centauri

Science.gov (United States)

Haggard, Daryl; Cool, A.; Heinke, C. O.; Cohn, H. N.; Lugger, P. M.; Van Der Marel, R. P.; Anderson, J.

2013-04-01

Omega Centauri, the Milky Way's most massive and enigmatic old stellar cluster, offers a treasure trove of astronomical discovery and controversy, including debate about the existence of an intermediate mass black hole (IMBH) buried in the cluster's core. We report preliminary results of deep 290 ksec) Chandra ACIS-I imaging of Omega Cen, which reveals no X-ray source at the cluster center reported by Anderson and van der Marel (2010), or at any other proposed center for the cluster. We discuss the significance of this new X-ray limit for the possible presence of an IMBH in Omega Cen. We also briefly describe our multiwavelength imaging and spectroscopic campaigns, which probe Omega Cen's binary populations, and the light they shed on the cluster's dynamical history.

Carbon and nitrogen assimilation in deep subseafloor microbial cells

OpenAIRE

Morono, Yuki; Terada, Takeshi; Nishizawa, Manabu; Ito, Motoo; Hillion, François; Takahata, Naoto; Sano, Yuji; Inagaki, Fumio

2011-01-01

Remarkable numbers of microbial cells have been observed in global shallow to deep subseafloor sediments. Accumulating evidence indicates that deep and ancient sediments harbor living microbial life, where the flux of nutrients and energy are extremely low. However, their physiology and energy requirements remain largely unknown. We used stable isotope tracer incubation and nanometer-scale secondary ion MS to investigate the dynamics of carbon and nitrogen assimilation activities in individua...

Chandra resolves the T Tauri binary system RW Aur

Energy Technology Data Exchange (ETDEWEB)

Skinner, Stephen L. [CASA, University of Colorado, Boulder, CO 80309-0389 (United States); Güdel, Manuel, E-mail: stephen.skinner@colorado.edu, E-mail: manuel.guedel@univie.ac.at [Department of Astrophysics, University of Vienna, Türkenschanzstr. 17, A-1180 Vienna (Austria)

2014-06-20

RW Aur is a multiple T Tauri system consisting of an early-K type primary (A) and a K5 companion (B) at a separation of 1.''4. RW Aur A drives a bipolar optical jet that is well characterized optically. We present results of a sensitive Chandra observation whose primary objective was to search for evidence of soft extended X-ray emission along the jet, as has been seen for a few other nearby T Tauri stars. The binary is clearly resolved by Chandra and both stars are detected as X-ray sources. The X-ray spectra of both stars reveal evidence for cool and hot plasma. Surprisingly, the X-ray luminosity of the less-massive secondary is at least twice that of the primary and is variable. The disparity is attributed to the primary whose X-ray luminosity is at the low end of the range for classical T Tauri stars of similar mass based on established correlations. Deconvolved soft-band images show evidence for slight outward elongation of the source structure of RW Aur A along the blueshifted jet axis inside the central arcsecond. In addition, a faint X-ray emission peak is present on the redshifted axis at an offset of 1.''2 ± 0.''2 from the star. Deprojected jet speeds determined from previous optical studies are too low to explain this faint emission peak as shock-heated jet plasma. Thus, unless flow speeds in the redshifted jet have been underestimated, other mechanisms such as magnetic jet heating may be involved.

Searching for faint AGN in the CDFS: an X-ray (Chandra) vs optical variability (HST) comparison.

Science.gov (United States)

Georgantopoulos, I.; Pouliasis, E.; Bonanos, A.; Sokolovsky, K.; Yang, M.; Hatzidimitriou, D.; Bellas, I.; Gavras, P.; Spetsieri, Z.

2017-10-01

X-ray surveys are believed to be the most efficient way to detect AGN. Recently though, optical variability studies are claimed to probe even fainter AGN. We are presenting results from an HST study aimed to identify Active Galactic Nuclei (AGN) through optical variability selection in the CDFS.. This work is part of the 'Hubble Catalogue of Variables'project of ESA that aims to identify variable sources in the Hubble Source Catalogue.' In particular, we used Hubble Space Telescope (HST) z-band images taken over 5 epochs and performed aperture photometry to derive the lightcurves of the sources. Two statistical methods (standard deviation & interquartile range) resulting in a final sample of 175 variable AGN candidates, having removed the artifacts by visual inspection and known stars and supernovae. The fact that the majority of the sources are extended and variable indicates AGN activity. We compare the efficiency of the method by comparing with the 7Ms Chandra detections. Our work shows that the optical variability probes AGN at comparable redshifts but at deeper optical magnitudes. Our candidate AGN (non detected in X-rays) have luminosities of L_x<6×10^{40} erg/sec at z˜0.7 suggesting that these are associated with low luminosity Seyferts and LINERS.

M Stars in the TW Hydra Association: A Chandra Large Program Survey

Science.gov (United States)

Punzi, Kristina; Kastner, Joel; Principe, David; Stelzer, Beate; Gorti, Uma; Pascucci, Illaria; Argiroffi, Costanza

2018-01-01

We have conducted a Cycle 18 Chandra Large Program survey of very cool members of the $\\sim$ 8 Myr-old TW Hydra Association (TWA) to extend our previous study of the potential connections between M star disks and X-rays (Kastner et al. 2016, AJ, 152, 3) to the extreme low-mass end of the stellar initial mass function. The spectral types of our targets extend down to the M/L borderline. Thus we can further investigate the potential connection between the intense X-ray emission from young, low-mass stars and the lifetimes of their circumstellar planet-forming discs, as well as better constrain the age at which coronal activity declines for stellar masses approaching the H-burning limit of $\\sim$ 0.08 M$_{\\odot}$. We present preliminary results from the Cycle 18 survey, including X-ray detection statistics and measurements of relative X-ray luminosities and coronal (X-ray) temperatures for those TWA stars detected by Chandra. This research is supported by SAO/CXC grant GO7-18002A and NASA Astrophysics Data Analysis program grants NNX12AH37G and NNX16AG13G to RIT.

Determination of the charm-quark mass in the MS scheme using charm production data from deep inelastic scattering at HERA

Energy Technology Data Exchange (ETDEWEB)

Alekhin, S. [Institut Fiziki Vysokikh Ehnergij, Protvino (Russian Federation); Daum, K [Wuppertal Univ. (Germany); Lipka, K. [Deutsches Elektronen-Synchrotron (DESY), Hamburg (Germany); Moch, S. [Deutsches Elektronen-Synchrotron (DESY), Zeuthen (Germany)

2012-08-15

We determine the charm-quark mass m{sub c}(m{sub c}) in the MS scheme using measurements of charm production in deep-inelastic ep scattering at HERA in the kinematic range of photon virtuality 5 GeV{sup 2}

CHANDRA HIGH-ENERGY TRANSMISSION GRATING SPECTRUM OF AE AQUARII

International Nuclear Information System (INIS)

Mauche, Christopher W.

2009-01-01

The nova-like cataclysmic binary AE Aqr, which is currently understood to be a former supersoft X-ray binary and current magnetic propeller, was observed for over two binary orbits (78 ks) in 2005 August with the High-Energy Transmission Grating (HETG) on board the Chandra X-ray Observatory. The long, uninterrupted Chandra observation provides a wealth of details concerning the X-ray emission of AE Aqr, many of which are new and unique to the HETG. First, the X-ray spectrum is that of an optically thin multi-temperature thermal plasma; the X-ray emission lines are broad, with widths that increase with the line energy from σ ∼ 1 eV (510 km s -1 ) for O VIII to σ ∼ 5.5 eV (820 km s -1 ) for Si XIV; the X-ray spectrum is reasonably well fit by a plasma model with a Gaussian emission measure distribution that peaks at log T(K) = 7.16, has a width σ = 0.48, an Fe abundance equal to 0.44 times solar, and other metal (primarily Ne, Mg, and Si) abundances equal to 0.76 times solar; and for a distance d = 100 pc, the total emission measure EM = 8.0 x 10 53 cm -3 and the 0.5-10 keV luminosity L X = 1.1 x 10 31 erg s -1 . Second, based on the f/(i + r) flux ratios of the forbidden (f), intercombination (i), and recombination (r) lines of the Heα triplets of N VI, O VII, and Ne IX measured by Itoh et al. in the XMM-Newton Reflection Grating Spectrometer spectrum and those of O VII, Ne IX, Mg XI, and Si XIII in the Chandra HETG spectrum, either the electron density of the plasma increases with temperature by over three orders of magnitude, from n e ∼ 6 x 10 10 cm -3 for N VI [log T(K) ∼ 6] to n e ∼ 1 x 10 14 cm -3 for Si XIII [log T(K) ∼ 7], and/or the plasma is significantly affected by photoexcitation. Third, the radial velocity of the X-ray emission lines varies on the white dwarf spin phase, with two oscillations per spin cycle and an amplitude K ∼ 160 km s -1 . These results appear to be inconsistent with the recent models of Itoh et al., Ikhsanov, and

Chandra and XMM–Newton Observations of H2O Maser Galaxy Mrk ...

Indian Academy of Sciences (India)

component, another power-law ( = 2.45 ± 0.07) for the soft component and a narrow Gaussian fitted to the Fe Kα line (EW∼48 eV) (see Fig. 2). The common model for Seyfert 2 and the above models cannot be well-fitted with the Chandra spectra. Residuals in terms of sigma show significant excess in 2–4 KeV and over 8 ...

THE VLA SURVEY OF CHANDRA DEEP FIELD SOUTH. V. EVOLUTION AND LUMINOSITY FUNCTIONS OF SUB-MILLIJANSKY RADIO SOURCES AND THE ISSUE OF RADIO EMISSION IN RADIO-QUIET ACTIVE GALACTIC NUCLEI

International Nuclear Information System (INIS)

Padovani, P.; Mainieri, V.; Rosati, P.; Miller, N.; Kellermann, K. I.; Tozzi, P.

2011-01-01

We present the evolutionary properties and luminosity functions of the radio sources belonging to the Chandra Deep Field South Very Large Array survey, which reaches a flux density limit at 1.4 GHz of 43 μJy at the field center and redshift ∼5 and which includes the first radio-selected complete sample of radio-quiet active galactic nuclei (AGNs). We use a new, comprehensive classification scheme based on radio, far- and near-IR, optical, and X-ray data to disentangle star-forming galaxies (SFGs) from AGNs and radio-quiet from radio-loud AGNs. We confirm our previous result that SFGs become dominant only below 0.1 mJy. The sub-millijansky radio sky turns out to be a complex mix of SFGs and radio-quiet AGNs evolving at a similar, strong rate; non-evolving low-luminosity radio galaxies; and declining radio powerful (P ∼> 3 x 10 24 W Hz -1 ) AGNs. Our results suggest that radio emission from radio-quiet AGNs is closely related to star formation. The detection of compact, high brightness temperature cores in several nearby radio-quiet AGNs can be explained by the coexistence of two components, one non-evolving and AGN related and one evolving and star formation related. Radio-quiet AGNs are an important class of sub-millijansky sources, accounting for ∼30% of the sample and ∼60% of all AGNs, and outnumbering radio-loud AGNs at ∼< 0.1 mJy. This implies that future, large area sub-millijansky surveys, given the appropriate ancillary multiwavelength data, have the potential of being able to assemble vast samples of radio-quiet AGNs, bypassing the problems of obscuration that plague the optical and soft X-ray bands.

CHANDRA AND SUZAKU OBSERVATIONS OF THE Be/X-RAY STAR HD110432

International Nuclear Information System (INIS)

Torrejón, J. M.; Schulz, N. S.; Nowak, M. A.

2012-01-01

We present an analysis of a pointed 141 ks Chandra high-resolution transmission gratings observation of the Be X-ray emitting star HD110432, a prominent member of the γ Cas analogs. This observation represents the first high-resolution spectrum taken for this source as well as the longest uninterrupted observation of any γ Cas analog. The Chandra light curve shows a high variability but its analysis fails to detect any coherent periodicity up to a frequency of 0.05 Hz. Hardness ratio versus intensity analyses demonstrate that the relative contributions of the [1.5-3] Å, [3-6] Å, and [6-16] Å energy bands to the total flux change rapidly in the short term. The analysis of the Chandra High Energy Transmission Grating (HETG) spectrum shows that, to correctly describe the spectrum, three model components are needed. Two of those components are optically thin thermal plasmas of different temperatures (kT ≈ 8-9 and 0.2-0.3 keV, respectively) described by the models vmekal or bvapec. The Fe abundance in each of these two components appears equal within the errors and is slightly subsolar with Z ≈ 0.75 Z ☉ . The bvapec model better describes the Fe L transitions, although it cannot fit well the Na XI Lyα line at 10.02 Å, which appears to be overabundant. Two different models seem to describe well the third component. One possibility is a third hot optically thin thermal plasma at kT = 16-21 keV with an Fe abundance Z ≈ 0.3 Z ☉ , definitely smaller than for the other two thermal components. Furthermore, the bvapec model describes well the Fe K shell transitions because it accounts for the turbulence broadening of the Fe XXV and Fe XXVI lines with a v turb ≈ 1200 km s –1 . These two lines, contributed mainly by the hot thermal plasma, are significantly wider than the Fe Kα line whose FWHM ☉ , and a very hot second plasma with kT ≈ 33 keV or, alternatively, a power law with photon index of Γ = 1.58. In either case, each one of the two components

The Chandra Source Catalog: Algorithms

Science.gov (United States)

McDowell, Jonathan; Evans, I. N.; Primini, F. A.; Glotfelty, K. J.; McCollough, M. L.; Houck, J. C.; Nowak, M. A.; Karovska, M.; Davis, J. E.; Rots, A. H.; Siemiginowska, A. L.; Hain, R.; Evans, J. D.; Anderson, C. S.; Bonaventura, N. R.; Chen, J. C.; Doe, S. M.; Fabbiano, G.; Galle, E. C.; Gibbs, D. G., II; Grier, J. D.; Hall, D. M.; Harbo, P. N.; He, X.; Lauer, J.; Miller, J. B.; Mitschang, A. W.; Morgan, D. L.; Nichols, J. S.; Plummer, D. A.; Refsdal, B. L.; Sundheim, B. A.; Tibbetts, M. S.; van Stone, D. W.; Winkelman, S. L.; Zografou, P.

2009-09-01

Creation of the Chandra Source Catalog (CSC) required adjustment of existing pipeline processing, adaptation of existing interactive analysis software for automated use, and development of entirely new algorithms. Data calibration was based on the existing pipeline, but more rigorous data cleaning was applied and the latest calibration data products were used. For source detection, a local background map was created including the effects of ACIS source readout streaks. The existing wavelet source detection algorithm was modified and a set of post-processing scripts used to correct the results. To analyse the source properties we ran the SAO Traceray trace code for each source to generate a model point spread function, allowing us to find encircled energy correction factors and estimate source extent. Further algorithms were developed to characterize the spectral, spatial and temporal properties of the sources and to estimate the confidence intervals on count rates and fluxes. Finally, sources detected in multiple observations were matched, and best estimates of their merged properties derived. In this paper we present an overview of the algorithms used, with more detailed treatment of some of the newly developed algorithms presented in companion papers.

Study on Seismogenesis of 2013 Ms5.1 Badong Earthquake in the Three Gorges Reservoir Region

Science.gov (United States)

Li, X.; Zeng, Z.; Xu, S.; He, C.

2015-12-01

On 16 December, 2013, an earthquake of Ms5.1 occurred in Badong County, the Three Gorges Reservoir area, China. We collected all the 150 published focal mechanism solutions (FMS) and inversed the tectonic stress field in Badong, the Three Gorges Dam and Huangling anticline area using the software SATSI (Hardebeck and Michael, 2006). Inversion results show that the orientations of maximum principle stress axis (σ1) in Badong plunge to NNE or SSW. Detailed characteristics of the stress field indicate that the σ1 axis is almost vertical in the center of Huangling anticline and turns horizontal to the west. As to deep structures, we studied the satellite gravity anomalies of 8-638 order in this area using the EIGEN-6C2 model provided by ICGRM. Combining the seismic sounding profile through the epicenter of Badong earthquake and the petrology data, we reinterpreted the deep structure in the study area. The results show that the deep crust in Badong is unstable and the deep material's upwelling leads to Huangling anticline continued uplifting, which is consistent with the result indicated from the stress filed. Both of them provide energy for the preparation of earthquake. The FMS shows that Gaoqiao Fault is the causative fault of this Ms5.1 earthquake. Field investigations indicated that the lithology and fracture characteristic in Badong is beneficial to reservoir water infiltration. Before the earthquake, reservoir water level raised to 175m, the highest storage level, which increased the loading. Based on above researches, we believe that the Ms5.1 Badong earthquake is controlled by deep tectonic environment and stress field in shallow crust. The reservoir water infiltration and uploading increase generated by water storage of the Three Gorges area reduced the strength of Gaoqiao Fault and changed its stress state. These factors jointly promoted an abrupt movement of the fault in the critical stress state, and triggered the Ms5.1 Badong earthquake.

Monitoring of the Crab Nebula with Chandra and Other Observatories Including HST

Science.gov (United States)

Weisskopf, Martin C.

2014-01-01

Subsequent to the detections AGILE and Fermi/LAT of the gamma-ray flares from the Crab Nebula in the fall of 2010, this team has been monitoring the X-Ray emission from the Crab on a regular basis. X-Ray observations have taken place typically once per month when viewing constraints allow and more recently four times per year. There have been notable exceptions, e.g. in April of 2011 and March 2013 when we initiated a set of Chandra Target of opportunity observations in conjunction with bright gamma-ray flares. For much of the time regular HST observations were made in conjunction with the Chandra observations. The aim of this program to further characterize, in depth, the X-Ray and optical variations that take place in the nebula, and by so doing determine the regions which contribute to the harder X-ray variations and, if possible, determine the precise location within the Nebula of the origin of the gamma-ray flares. As part of this project members of the team have developed Singular Value Decomposition techniques to sequences of images in order to more accurately characterize features. The current status of the project will be presented highlighting studies of the inner knot and possible correlations with the flares.

Chandra's Observations of Jupiter's X-Ray Aurora During Juno Upstream and Apojove Intervals

Science.gov (United States)

Jackman, C.M.; Dunn, W.; Kraft, R.; Gladstone, R.; Branduardi-Raymont, G.; Knigge, C.; Altamirano, D.; Elsner, R.

2017-01-01

The Chandra space telescope has recently conducted a number of campaigns to observe Jupiter's X-ray aurora. The first set of campaigns took place in summer 2016 while the Juno spacecraft was upstream of the planet sampling the solar wind. The second set of campaigns took place in February, June and August 2017 at times when the Juno spacecraft was at apojove (expected close to the magnetopause). We report on these upstream and apojove campaigns including intensities and periodicities of auroral X-ray emissions. This new era of jovian X-ray astronomy means we have more data than ever before, long observing windows (up to 72 kiloseconds for this Chandra set), and successive observations relatively closely spaced in time. These features combine to allow us to pursue novel methods for examining periodicities in the X-ray emission. Our work will explore significance testing of emerging periodicities, and the search for coherence in X-ray pulsing over weeks and months, seeking to understand the robustness and regularity of previously reported hot spot X-ray emissions. The periods that emerge from our analysis will be compared against those which emerge from radio and UV wavelengths.

Shocks and cold fronts in merging and massive galaxy clusters: new detections with Chandra

Science.gov (United States)

Botteon, A.; Gastaldello, F.; Brunetti, G.

2018-06-01

A number of merging galaxy clusters show the presence of shocks and cold fronts, i.e. sharp discontinuities in surface brightness and temperature. The observation of these features requires an X-ray telescope with high spatial resolution like Chandra, and allows to study important aspects concerning the physics of the intracluster medium (ICM), such as its thermal conduction and viscosity, as well as to provide information on the physical conditions leading to the acceleration of cosmic rays and magnetic field amplification in the cluster environment. In this work we search for new discontinuities in 15 merging and massive clusters observed with Chandra by using different imaging and spectral techniques of X-ray observations. Our analysis led to the discovery of 22 edges: six shocks, eight cold fronts, and eight with uncertain origin. All the six shocks detected have Mdiverse approaches aimed to identify edges in the ICM. A radio follow-up of the shocks discovered in this paper will be useful to study the connection between weak shocks and radio relics.

Detecting Multi-scale Structures in Chandra Images of Centaurus A

Science.gov (United States)

Karovska, M.; Fabbiano, G.; Elvis, M. S.; Evans, I. N.; Kim, D. W.; Prestwich, A. H.; Schwartz, D. A.; Murray, S. S.; Forman, W.; Jones, C.; Kraft, R. P.; Isobe, T.; Cui, W.; Schreier, E. J.

1999-12-01

Centaurus A (NGC 5128) is a giant early-type galaxy with a merger history, containing the nearest radio-bright AGN. Recent Chandra High Resolution Camera (HRC) observations of Cen A reveal X-ray multi-scale structures in this object with unprecedented detail and clarity. We show the results of an analysis of the Chandra data with smoothing and edge enhancement techniques that allow us to enhance and quantify the multi-scale structures present in the HRC images. These techniques include an adaptive smoothing algorithm (Ebeling et al 1999), and a multi-directional gradient detection algorithm (Karovska et al 1994). The Ebeling et al adaptive smoothing algorithm, which is incorporated in the CXC analysis s/w package, is a powerful tool for smoothing images containing complex structures at various spatial scales. The adaptively smoothed images of Centaurus A show simultaneously the high-angular resolution bright structures at scales as small as an arcsecond and the extended faint structures as large as several arc minutes. The large scale structures suggest complex symmetry, including a component possibly associated with the inner radio lobes (as suggested by the ROSAT HRI data, Dobereiner et al 1996), and a separate component with an orthogonal symmetry that may be associated with the galaxy as a whole. The dust lane and the x-ray ridges are very clearly visible. The adaptively smoothed images and the edge-enhanced images also suggest several filamentary features including a large filament-like structure extending as far as about 5 arcminutes to North-West.

Large Scale Structures in the GOODS-SOUTH Field up to z~2.5

Science.gov (United States)

Trevese, D.; Castellano, M.; Salimbeni, S.; Pentericci, L.; Fiore, F.

2009-05-01

We apply a density evaluation technique based on photometric redshifts, developed by our group, to estimate galaxy space density on the deep (z450~26) multi-wavelength GOODS-MUSIC catalogue. We find several groups and clusters in the redshift range 0.4-2.5. We present here an outline of the X-ray properties of our cluster sample as computed from the Chandra 2Ms data. A group at z = 0.96 could be associated to an extended X-ray source, while two clusters with masses of few times 1014Msolar have upper limits on their X-ray emission significantly lower than expected from their optical properties.

Modeling Contamination Migration on the Chandra X-ray Observatory - II

Science.gov (United States)

O'Dell, Stephen L.; Swartz, Douglas A.; Tice, Neil W.; Plucinsky, Paul P.; Grant, Catherine E.; Marshall, Herman L.; Vikhlinin, Alexey A.; Tennant, Allyn F.

2013-01-01

During its first 14 years of operation, the cold (about -60C) optical blocking filter of the Advanced CCD Imaging Spectrometer (ACIS), aboard the Chandra X-ray Observatory, has accumulated a growing layer of molecular contamination that attenuates low-energy x rays. Over the past few years, the accumulation rate, spatial distribution, and composition have changed. This evolution has motivated further analysis of contamination migration within and near the ACIS cavity. To this end, the current study employs a higher-fidelity geometric model of the ACIS cavity, detailed thermal modeling based upon temperature data, and a refined model of the molecular transport.

Modeling Contamination Migration on the Chandra X-Ray Observatory - III

Science.gov (United States)

O'Dell, Stephen L.; Swartz, Douglas A.; Tice, Neil W.; Plucinsky, Paul P.; Grant, Catherine E.; Marshall, Herman L.; Vikhlinin, Alexy A.; Tennant, Allyn F.; Dahmer, Matthew T.

2015-01-01

During its first 16 years of operation, the cold (about -60 C) optical blocking filter of the Advanced CCD Imaging Spectrometer (ACIS), aboard the Chandra X-ray Observatory, has accumulated a growing layer of molecular contamination that attenuates low-energy x rays. Over the past few years, the accumulation rate, spatial distribution, and composition have changed. This evolution has motivated further analysis of contamination migration within and near the ACIS cavity, in part to evaluate potential bake-out scenarios intended to reduce the level of contamination. Keywords: X-ray astronomy, CCDs, contamination, modeling and simulation, spacecraft operations

Analytic parameter dependence of Harish-Chandra modules for real reductive Lie groups - a family affair

NARCIS (Netherlands)

van der Noort, V.

2009-01-01

This thesis is written in the subfield of mathematics known as representation theory of real reductive Lie groups. Let G be a Lie group in the Harish-Chandra class with maximal compact subgroup K and Lie algebra g. Let Omega be a connected complex manifold. By a family of G-representations

CHANDRA OBSERVATION OF THE TeV SOURCE HESS J1834-087

International Nuclear Information System (INIS)

Misanovic, Zdenka; Kargaltsev, Oleg; Pavlov, George G.

2011-01-01

Chandra ACIS observed the field of the extended TeV source HESS J1834-087 for 47 ks. A previous XMM-Newton EPIC observation of the same field revealed a point-like source (XMMU J183435.3-084443) and an offset region of faint extended emission. In the low-resolution, binned EPIC images the two appear to be connected. However, the high-resolution Chandra ACIS images do not support the alleged connection. In these images, XMMU J183435.3-084443 is resolved into a point source, CXOU J183434.9-084443 (L 0.5-8keV ≅ 2.3 x 10 33 erg s -1 , for a distance of 4 kpc; photon index Γ ≅ 1.1), and a compact (∼ 0.5-8keV ≅ 4.1 x 10 33 erg s -1 , Γ ≅ 2.7). The nature of the nebula is uncertain. We discuss a dust scattering halo and a pulsar-wind nebula as possible interpretations. Based on our analysis of the X-ray data, we re-evaluate the previously suggested interpretations of HESS J1834-087 and discuss a possible connection to the Fermi Large Area Telescope source 1FGL J1834.3-0842c. We also obtained an upper limit of 3 x 10 -14 erg cm -2 s -1 on the unabsorbed flux of the SGR J1833-0832 (in quiescence), which happened to be in the ACIS field of view.

PENGARUH PEMERIKSAAN INTERN TERHADAP EFEKTIVITAS PENGENDALIAN INTERN ATAS PERSEDIAAN BAHAN BAKU PADA PT. CHANDRA ASRI PETROCHEMICAL JAKARTA

Directory of Open Access Journals (Sweden)

Andi Riyanto

2016-03-01

  Keyword : Raw Material Inventory, Internal Control, Internal Auditing.   Abstrak - PT. Chandra Asri Petrochemical adalah perusahaan petrokimia terbesar dan terintegrasi secara vertikal di Indonesia. Tujuan penelitian ini adalah untuk mengetahui pengaruh pemeriksaan intern terhadap efektivitas pengendalian intern atas persediaan bahan baku pada PT. Chandra Asri Petrochemical. Metode yang digunakan adalah metode deskriptif analitis dengan pendekatan kuantitatif. Populasi berjumlah 27 pegawai dan semua populasi digunakan sebagai sampel dengan teknik sampling jenuh. Dari perhitungan uji statistik menggunakan aplikasi SPSS versi 20, diperoleh nilai thitung untuk variabel pemeriksaan intern adalah 5,799 dengan df = 24 pada signifikansi (α 0,05, diperoleh ttabel sebesar 2,064, maka keputusan uji yang diambil adalah H0 ditolak. Artinya bahwa pemeriksaan intern berpengaruh signifikan terhadap efektivitas pengendalian intern atas persediaan bahan baku.   Kata Kunci : Pemeriksaan Intern, Pengendalian Intern, Persediaan Bahan Baku.

Accreting Binary Populations in the Earlier Universe

Science.gov (United States)

Hornschemeier, Ann

2010-01-01

It is now understood that X-ray binaries dominate the hard X-ray emission from normal star-forming galaxies. Thanks to the deepest (2-4 Ms) Chandra surveys, such galaxies are now being studied in X-rays out to z approximates 4. Interesting X-ray stacking results (based on 30+ galaxies per redshift bin) suggest that the mean rest-frame 2-10 keV luminosity from z=3-4 Lyman break galaxies (LBGs), is comparable to the most powerful starburst galaxies in the local Universe. This result possibly indicates a similar production mechanism for accreting binaries over large cosmological timescales. To understand and constrain better the production of X-ray binaries in high-redshift LBGs, we have utilized XMM-Newton observations of a small sample of z approximates 0.1 GALEX-selected Ultraviolet-Luminous Galaxies (UVLGs); local analogs to high-redshift LBGs. Our observations enable us to study the X-ray emission from LBG-like galaxies on an individual basis, thus allowing us to constrain object-to-object variances in this population. We supplement these results with X-ray stacking constraints using the new 3.2 Ms Chandra Deep Field-South (completed spring 2010) and LBG candidates selected from HST, Swift UVOT, and ground-based data. These measurements provide new X-ray constraints that sample well the entire z=0-4 baseline

3T deep gray matter T2 hypointensity correlates with disability over time in stable relapsing-remitting multiple sclerosis: a 3-year pilot study.

Science.gov (United States)

Zhang, Y; Metz, L M; Yong, V W; Mitchell, J R

2010-10-15

Abnormally decreased deep gray matter (GM) signal intensity on T2-weighted MRI (T2 hypointensity) is associated with brain atrophy and disability progression in patients with multiple sclerosis (MS) and is believed to represent excessive iron deposition. We investigated the time course of deep GM T2 hypointensity and its relationship with disability at 3T in 8 stable relapsing-remitting (RR) MS patients treated with minocycline over 3years. MRI and disability measurements were compared at baseline, 6, 12, 24, and 36months. Grand mean deep GM T2 hypointensity was negatively correlated with EDSS over time (r=-0.94, P=0.02). This correlation was strongest in the head of caudate (r=-0.95, P=0.01) and putamen (r=-0.89, P=0.04). Additionally, baseline grand mean deep GM T2 hypointensity appears to predict third year EDSS (r=-0.72, P=0.04). These results suggest that iron associated deep GM injury correlates with patient disability in stable RRMS. Measurements of deep GM T2 hypointensity at high field MRI may prove to be useful in monitoring individuals with MS. Further studies are required to confirm these results in a large sample and to determine if T2 hypointensity changes in clinically active MS patients. Copyright 2010 Elsevier B.V. All rights reserved.

The Nature of the Unresolved Extragalactic Cosmic Soft X-Ray Background

Science.gov (United States)

Cappelluti, N.; Ranalli, P.; Roncarelli, M.; Arevalo, P.; Zamorani, G.; Comastri, A.; Gilli, R.; Rovilos, E.; Vignali, C.; Allevato, V.;

CHANDRA OBSERVATIONS OF THE HIGH-MAGNETIC-FIELD RADIO PULSAR J1718-3718

International Nuclear Information System (INIS)

Zhu, W. W.; Kaspi, V. M.; Ng, C.-Y.; McLaughlin, M. A.; Pavlov, G. G.; Manchester, R. N.; Gaensler, B. M.; Woods, P. M.

2011-01-01

High-magnetic-field pulsars represent an important class of objects for studying the relationship between magnetars and radio pulsars. Here we report on four Chandra observations of the high-magnetic-field pulsar J1718-3718 (B = 7.4 x 10 13 G) taken in 2009 as well as a reanalysis of 2002 Chandra observations of the region. We also report an improved radio position for this pulsar based on ATCA observations. We detect X-ray pulsations at the pulsar's period in the 2009 data, with a pulsed fraction of 52% ± 13% in the 0.8-2.0 keV band. We find that the X-ray pulse is aligned with the radio pulse. The data from 2002 and 2009 show consistent spectra and fluxes: a merged overall spectrum is well fit by a blackbody of temperature 186 +19 -18 eV, slightly higher than predicted by standard cooling models; however, the best-fit neutron star atmosphere model is consistent with standard cooling. We find the bolometric luminosity L ∞ bb = 4 +5 -2 x 10 32 erg s -1 ∼0.3 E-dot for a distance of 4.5 kpc. We compile measurements of the temperatures of all X-ray-detected high-B pulsars as well as those of low-B radio pulsars and find evidence for the former being hotter on average than the latter.

NuSTAR J033202-2746.8: Direct constraints on the Compton reflection in a heavily obscured quasar at z ≈ 2

Energy Technology Data Exchange (ETDEWEB)

Del Moro, A.; Mullaney, J. R.; Alexander, D. M.; Aird, J. A.; Gandhi, P. [Department of Physics, Durham University, South Road, Durham, DH1 3LE (United Kingdom); Comastri, A.; Vignali, C.; Gilli, R. [INAF-Osservatorio Astronomico di Bologna, Via Ranzani 1, I-40127 Bologna (Italy); Bauer, F. E. [Instituto de Astrofísica, Facultad de Física, Pontificia Universidad Católica de Chile, 306, Santiago 22 (Chile); Treister, E. [Departamento de Astronomía, Universidad de Concepción, Casilla 160-C, Concepción (Chile); Stern, D. [Jet Propulsion Laboratory, California Institute of Technology, 4800 Oak Grove Drive, Mail Stop 169-221, Pasadena, CA 91109 (United States); Civano, F. [Department of Physics and Astronomy, Dartmouth College, 6127 Wilder Laboratory, Hanover, NH 03755 (United States); Ranalli, P. [National Observatory of Athens, Institute of Astronomy, Astrophysics, Space Applications and Remote Sensing, Metaxa and Pavlou St., 15236 Penteli (Greece); Ballantyne, D. R. [Center for Relativistic Astrophysics, School of Physics, Georgia Institute of Technology, Atlanta, GA 30332 (United States); Baloković, M. [Cahill Center for Astrophysics, 1216 East California Boulevard, California Institute of Technology, Pasadena, CA 91125 (United States); Boggs, S. E. [Space Sciences Laboratory, University of California, Berkeley, CA 94720 (United States); Brandt, W. N. [Department of Astronomy and Astrophysics, 525 Davey Lab, The Pennsylvania State University, University Park, PA 16802 (United States); Christensen, F. E. [DTU Space-National Space Institute, Technical University of Denmark, Elektrovej 327, DK-2800 Lyngby (Denmark); Craig, W. W. [Lawrence Livermore National Laboratory, Livermore, CA 94550 (United States); Hailey, C. J., E-mail: agnese.del-moro@durham.ac.uk [Columbia Astrophysics Laboratory, 550 W 120th Street, Columbia University, NY 10027 (United States); and others

2014-05-01

We report Nuclear Spectroscopic Telescope Array (NuSTAR) observations of NuSTAR J033202-2746.8, a heavily obscured, radio-loud quasar detected in the Extended Chandra Deep Field-South, the deepest layer of the NuSTAR extragalactic survey (∼400 ks, at its deepest). NuSTAR J033202-2746.8 is reliably detected by NuSTAR only at E > 8 keV and has a very flat spectral slope in the NuSTAR energy band (Γ=0.55{sub −0.64}{sup +0.62}; 3-30 keV). Combining the NuSTAR data with extremely deep observations by Chandra and XMM-Newton (4 Ms and 3 Ms, respectively), we constrain the broad-band X-ray spectrum of NuSTAR J033202-2746.8, indicating that this source is a heavily obscured quasar (N{sub H}=5.6{sub −0.8}{sup +0.9}×10{sup 23} cm{sup –2}) with luminosity L {sub 10-40} {sub keV} ≈ 6.4 × 10{sup 44} erg s{sup –1}. Although existing optical and near-infrared (near-IR) data, as well as follow-up spectroscopy with the Keck and VLT telescopes, failed to provide a secure redshift identification for NuSTAR J033202-2746.8, we reliably constrain the redshift z = 2.00 ± 0.04 from the X-ray spectral features (primarily from the iron K edge). The NuSTAR spectrum shows a significant reflection component (R=0.55{sub −0.37}{sup +0.44}), which was not constrained by previous analyses of Chandra and XMM-Newton data alone. The measured reflection fraction is higher than the R ∼ 0 typically observed in bright radio-loud quasars such as NuSTAR J033202-2746.8, which has L {sub 1.4} {sub GHz} ≈ 10{sup 27} W Hz{sup –1}. Constraining the spectral shape of active galactic nuclei (AGNs), including bright quasars, is very important for understanding the AGN population, and can have a strong impact on the modeling of the X-ray background. Our results show the importance of NuSTAR in investigating the broad-band spectral properties of quasars out to high redshift.

Using the Chandra Source-Finding Algorithm to Automatically Identify Solar X-ray Bright Points

Science.gov (United States)

Adams, Mitzi L.; Tennant, A.; Cirtain, J. M.

2009-01-01

This poster details a technique of bright point identification that is used to find sources in Chandra X-ray data. The algorithm, part of a program called LEXTRCT, searches for regions of a given size that are above a minimum signal to noise ratio. The algorithm allows selected pixels to be excluded from the source-finding, thus allowing exclusion of saturated pixels (from flares and/or active regions). For Chandra data the noise is determined by photon counting statistics, whereas solar telescopes typically integrate a flux. Thus the calculated signal-to-noise ratio is incorrect, but we find we can scale the number to get reasonable results. For example, Nakakubo and Hara (1998) find 297 bright points in a September 11, 1996 Yohkoh image; with judicious selection of signal-to-noise ratio, our algorithm finds 300 sources. To further assess the efficacy of the algorithm, we analyze a SOHO/EIT image (195 Angstroms) and compare results with those published in the literature (McIntosh and Gurman, 2005). Finally, we analyze three sets of data from Hinode, representing different parts of the decline to minimum of the solar cycle.

Advantages of automation in plasma sample preparation prior to HPLC/MS/MS quantification: application to the determination of cilazapril and cilazaprilat in a bioequivalence study.

Science.gov (United States)

Kolocouri, Filomila; Dotsikas, Yannis; Apostolou, Constantinos; Kousoulos, Constantinos; Soumelas, Georgios-Stefanos; Loukas, Yannis L

2011-01-01

An HPLC/MS/MS method characterized by complete automation and high throughput was developed for the determination of cilazapril and its active metabolite cilazaprilat in human plasma. All sample preparation and analysis steps were performed by using 2.2 mL 96 deep-well plates, while robotic liquid handling workstations were utilized for all liquid transfer steps, including liquid-liquid extraction. The whole procedure was very fast compared to a manual procedure with vials and no automation. The method also had a very short chromatographic run time of 1.5 min. Sample analysis was performed by RP-HPLC/MS/MS with positive electrospray ionization using multiple reaction monitoring. The calibration curve was linear in the range of 0.500-300 and 0.250-150 ng/mL for cilazapril and cilazaprilat, respectively. The proposed method was fully validated and proved to be selective, accurate, precise, reproducible, and suitable for the determination of cilazapril and cilazaprilat in human plasma. Therefore, it was applied to a bioequivalence study after per os administration of 2.5 mg tablet formulations of cilazapril.

THE CHANDRA X-RAY SURVEY OF PLANETARY NEBULAE (CHANPLANS): PROBING BINARITY, MAGNETIC FIELDS, AND WIND COLLISIONS

Energy Technology Data Exchange (ETDEWEB)

Kastner, J. H.; Montez, R. Jr.; Rapson, V. [Center for Imaging Science and Laboratory for Multiwavelength Astrophysics, Rochester Institute of Technology, 54 Lomb Memorial Drive, Rochester, NY 14623 (United States); Balick, B. [Department of Astronomy, University of Washington, Seattle, WA (United States); Frew, D. J.; De Marco, O.; Parker, Q. A. [Department of Physics and Astronomy and Macquarie Research Centre for Astronomy, Astrophysics and Astrophotonics, Macquarie University, Sydney, NSW 2109 (Australia); Miszalski, B. [South African Astronomical Observatory, P.O. Box 9, Observatory, 7935 (South Africa); Sahai, R. [Jet Propulsion Laboratory, California Institute of Technology, MS 183-900, Pasadena, CA 91109 (United States); Blackman, E.; Frank, A. [Department of Physics and Astronomy, University of Rochester, Rochester, NY (United States); Chu, Y.-H. [Department of Astronomy, University of Illinois, Champagne-Urbana, IL (United States); Guerrero, M. A. [Instituto de Astrofisica de Astronomia, Glorieta de la Astronomia s/n, Granada 18008 (Spain); Lopez, J. A. [Instituto de Astronomia, Universidad Nacional Autonoma de Mexico, Campus Ensenada, Apdo. Postal 22860, Ensenada, B. C. (Mexico); Zijlstra, A. [School of Physics and Astronomy, University of Manchester, Manchester M13 9PL (United Kingdom); Behar, E. [Department of Physics, Technion (Israel); Bujarrabal, V. [Observatorio Astronomico Nacional, Apartado 112, E-28803, Alcala de Henares (Spain); Corradi, R. L. M. [Instituto de Astrofisica de Canarias, E-38200 La Laguna, Tenerife (Spain); Nordhaus, J. [Center for Computational Relativity and Gravitation, Rochester Institute of Technology, Rochester, NY 14623 (United States); Sandin, C., E-mail: jhk@cis.rit.edu, E-mail: soker@physics.technion.ac.il, E-mail: eva.villaver@uam.es [Leibniz Institute for Astrophysics Potsdam (AIP), An der Sternwarte 16, D-14482 Potsdam (Germany); and others

2012-08-15

We present an overview of the initial results from the Chandra Planetary Nebula Survey (CHANPLANS), the first systematic (volume-limited) Chandra X-Ray Observatory survey of planetary nebulae (PNe) in the solar neighborhood. The first phase of CHANPLANS targeted 21 mostly high-excitation PNe within {approx}1.5 kpc of Earth, yielding four detections of diffuse X-ray emission and nine detections of X-ray-luminous point sources at the central stars (CSPNe) of these objects. Combining these results with those obtained from Chandra archival data for all (14) other PNe within {approx}1.5 kpc that have been observed to date, we find an overall X-ray detection rate of {approx}70% for the 35 sample objects. Roughly 50% of the PNe observed by Chandra harbor X-ray-luminous CSPNe, while soft, diffuse X-ray emission tracing shocks-in most cases, 'hot bubbles'-formed by energetic wind collisions is detected in {approx}30%; five objects display both diffuse and point-like emission components. The presence (or absence) of X-ray sources appears correlated with PN density structure, in that molecule-poor, elliptical nebulae are more likely to display X-ray emission (either point-like or diffuse) than molecule-rich, bipolar, or Ring-like nebulae. All but one of the point-like CSPNe X-ray sources display X-ray spectra that are harder than expected from hot ({approx}100 kK) central stars emitting as simple blackbodies; the lone apparent exception is the central star of the Dumbbell nebula, NGC 6853. These hard X-ray excesses may suggest a high frequency of binary companions to CSPNe. Other potential explanations include self-shocking winds or PN mass fallback. Most PNe detected as diffuse X-ray sources are elliptical nebulae that display a nested shell/halo structure and bright ansae; the diffuse X-ray emission regions are confined within inner, sharp-rimmed shells. All sample PNe that display diffuse X-ray emission have inner shell dynamical ages {approx}< 5 Multiplication

The Chandra planetary nebula survey (CHANPLANS). II. X-ray emission from compact planetary nebulae

Energy Technology Data Exchange (ETDEWEB)

Freeman, M.; Kastner, J. H. [Center for Imaging Science and Laboratory for Multiwavelength Astrophysics, Rochester Institute of Technology, 54 Lomb Memorial Drive, Rochester, NY 14623 (United States); Montez, R. Jr. [Department of Physics and Astronomy, Vanderbilt University, Nashville, TN (United States); Balick, B. [Department of Astronomy, University of Washington, Seattle, WA (United States); Frew, D. J.; De Marco, O.; Parker, Q. A. [Department of Physics and Astronomy and Macquarie Research Centre for Astronomy, Astrophysics and Astrophotonics, Macquarie University, Sydney, NSW 2109 (Australia); Jones, D. [Departamento de Física, Universidad de Atacama, Copayapu 485, Copiapó (Chile); Miszalski, B. [South African Astronomical Observatory, P.O. Box 9, Observatory, 7935 (South Africa); Sahai, R. [Jet Propulsion Laboratory, MS 183-900, California Institute of Technology, Pasadena, CA 91109 (United States); Blackman, E.; Frank, A. [Department of Physics and Astronomy, University of Rochester, Rochester, NY (United States); Chu, Y.-H. [Department of Astronomy, University of Illinois at Urbana-Champaign, Urbana, IL (United States); Guerrero, M. A. [Instituto de Astrofísica de Andalucía, IAA-CSIC, Glorieta de la Astronomía s/n, Granada, E-18008 (Spain); Lopez, J. A. [Instituto de Astronomía, Universidad Nacional Autonoma de Mexico, Campus Ensenada, Apdo. Postal 22860, Ensenada, B. C. (Mexico); Zijlstra, A. [School of Physics and Astronomy, University of Manchester, Manchester M13 9PL (United Kingdom); Bujarrabal, V. [Instituto de Astrofísica de Canarias, E-38200 La Laguna, Tenerife (Spain); Corradi, R. L. M. [Departamento de Astrofísica, Universidad de La Laguna, E-38206 La Laguna, Tenerife (Spain); Nordhaus, J. [NSF Astronomy and Astrophysics Fellow, Center for Computational Relativity and Gravitation, Rochester Institute of Technology, Rochester, NY 14623 (United States); and others

2014-10-20

We present results from the most recent set of observations obtained as part of the Chandra X-ray observatory Planetary Nebula Survey (CHANPLANS), the first comprehensive X-ray survey of planetary nebulae (PNe) in the solar neighborhood (i.e., within ∼1.5 kpc of the Sun). The survey is designed to place constraints on the frequency of appearance and range of X-ray spectral characteristics of X-ray-emitting PN central stars and the evolutionary timescales of wind-shock-heated bubbles within PNe. CHANPLANS began with a combined Cycle 12 and archive Chandra survey of 35 PNe. CHANPLANS continued via a Chandra Cycle 14 Large Program which targeted all (24) remaining known compact (R {sub neb} ≲ 0.4 pc), young PNe that lie within ∼1.5 kpc. Results from these Cycle 14 observations include first-time X-ray detections of hot bubbles within NGC 1501, 3918, 6153, and 6369, and point sources in HbDs 1, NGC 6337, and Sp 1. The addition of the Cycle 14 results brings the overall CHANPLANS diffuse X-ray detection rate to ∼27% and the point source detection rate to ∼36%. It has become clearer that diffuse X-ray emission is associated with young (≲ 5 × 10{sup 3} yr), and likewise compact (R {sub neb} ≲ 0.15 pc), PNe with closed structures and high central electron densities (n{sub e} ≳ 1000 cm{sup –3}), and is rarely associated with PNe that show H{sub 2} emission and/or pronounced butterfly structures. Hb 5 is one such exception of a PN with a butterfly structure that hosts diffuse X-ray emission. Additionally, two of the five new diffuse X-ray detections (NGC 1501 and NGC 6369) host [WR]-type central stars, supporting the hypothesis that PNe with central stars of [WR]-type are likely to display diffuse X-ray emission.

Imbalance in multiple sclerosis and neuromyelitis optica: association with deep sensation disturbance.

Science.gov (United States)

Demura, Yutaka; Kinoshita, Masako; Fukuda, Osamu; Nose, Shouzou; Nakano, Hitoshi; Juzu, Akira; Murase, Nagako; Yamamoto, Kenji

2016-12-01

Abnormality in balance is one of the most important causes of gait disturbance which has a direct impact to disability and medical cost in multiple sclerosis (MS) and neuromyelitis optica (NMO). However, characteristics of imbalance in these two diseases have not been fully elucidated. The aim of this study was to evaluate the degree and features of imbalance using stabilography, the degree of deep sensation disturbance using tibial nerve somatosensory evoked potentials (SEP), and their association with clinical impairment, in patients with MS and NMO. Seven NMO patients and seven MS patients with balance disturbance were examined. The relationship among stabilography measurements representing the degree and features of imbalance, height-adjusted P38 peak latency of SEP, and neurological functional disability, were analyzed. Stabilography evaluation showed a significantly severer degree of imbalance in NMO than in MS. Romberg quotient of the patients with brainstem lesions was significantly larger than those without them. In all patients, length of excursion per second significantly correlated positively with anterio-posterior-axis power spectra at intermediate frequency band. In all patients and in NMO, P38 peak latency adjusted by height significantly correlated positively with anterio-posterior-axis power spectra at intermediate frequency band. These findings suggest that the degree of imbalance of MS and NMO possibly correlate with deep sensation disturbance, which could be evaluated by anterio-posterior-axis power spectra at intermediate frequency band by stabilography. Severer imbalance in NMO than MS may be associated with the severe longitudinally extensive spinal cord lesions.

A Deep Chandra ACIS Study of NGC 4151. I. The X-ray Morphology of the 3 kpc Diameter Circum-nuclear Region and Relation to the Cold Interstellar Medium

Science.gov (United States)

Wang, Junfeng; Fabbiano, Giuseppina; Risaliti, Guido; Elvis, Martin; Karovska, Margarita; Zezas, Andreas; Mundell, Carole G.; Dumas, Gaelle; Schinnerer, Eva

2011-03-01

We report on the imaging analysis of ~200 ks sub-arcsecond resolution Chandra Advanced CCD Imaging Spectrometer (ACIS-S) observations of the nearby Seyfert 1 galaxy NGC 4151. Bright, structured soft X-ray emission is observed to extend from 30 pc to 1.3 kpc in the southwest from the nucleus, much farther than seen in earlier X-ray studies. The terminus of the northeastern X-ray emission is spatially coincident with a CO gas lane, where the outflow likely encounters dense gas in the host galactic disk. X-ray emission is also detected outside the boundaries of the ionization cone, which indicates that the gas there is not completely shielded from the nuclear continuum, as would be the case for a molecular torus collimating the bicone. In the central r < 200 pc region, the subpixel processing of the ACIS data recovers the morphological details on scales of <30 pc (<0farcs5) first discovered in Chandra High Resolution Camera images. The X-ray emission is more absorbed toward the boundaries of the ionization cone, as well as perpendicular to the bicone along the direction of a putative torus in NGC 4151. The innermost region where X-ray emission shows the highest hardness ratio is spatially coincident with the near-infrared-resolved H2 emission and dusty spirals we find in an Hubble Space Telescope V - H color image. The agreement between the observed H2 line flux and the value predicted from X-ray-irradiated molecular cloud models supports photo-excitation by X-rays from the active nucleus as the origin of the H2 line, although contribution from UV fluorescence or collisional excitation cannot be ruled out with current data. The discrepancy between the mass of cold molecular gas inferred from recent CO and near-infrared H2 observations may be explained by the anomalous CO abundance in this X-ray-dominated region. The total H2 mass derived from the X-ray observation agrees with the recent measurement by Storchi-Bergmann et al.

Chandra and RXTE studies of the X-ray/gamma-ray millisecond pulsar PSR J0218+4232

NARCIS (Netherlands)

Kuiper, L.; Hermsen, W.; Stappers, B.W.

2004-01-01

We report on high-resolution spatial and timing observations of the millisecond pulsar PSR J0218+4232 performed with the Chandra X-ray Observatory (CXO) and the Rossi X-ray Timing Explorer (RXTE). With these observations we were able to study: (a) the possible spatial extent at X-ray energies of the

CHANDRA OBSERVATIONS OF 3C RADIO SOURCES WITH z < 0.3. II. COMPLETING THE SNAPSHOT SURVEY

Energy Technology Data Exchange (ETDEWEB)

Massaro, F. [SLAC National Laboratory and Kavli Institute for Particle Astrophysics and Cosmology, 2575 Sand Hill Road, Menlo Park, CA 94025 (United States); Tremblay, G. R. [European Southern Observatory, Karl-Schwarzschild-Str. 2, D-85748 Garching bei Muenchen (Germany); Harris, D. E.; O' Dea, C. P. [Smithsonian Astrophysical Observatory, 60 Garden Street, Cambridge, MA 02138 (United States); Kharb, P.; Axon, D. [Department of Physics, Rochester Institute of Technology, Carlson Center for Imaging Science 76-3144, 84 Lomb Memorial Dr., Rochester, NY 14623 (United States); Balmaverde, B.; Capetti, A. [INAF-Osservatorio Astrofisico di Torino, Strada Osservatorio 20, I-10025 Pino Torinese (Italy); Baum, S. A. [Carlson Center for Imaging Science 76-3144, 84 Lomb Memorial Dr., Rochester, NY 14623 (United States); Chiaberge, M.; Macchetto, F. D.; Sparks, W. [Space Telescope Science Institute, 3700 San Martine Drive, Baltimore, MD 21218 (United States); Gilli, R. [INAF-Osservatorio Astronomico di Bologna, Via Ranzani 1, I-40127 Bologna (Italy); Giovannini, G. [INAF-Istituto di Radioastronomia di Bologna, Via Gobetti 101, I-40129 Bologna (Italy); Grandi, P.; Torresi, E. [INAF-IASF-Istituto di Astrofisica Spaziale e fisica Cosmica di Bologna, Via P. Gobetti 101, I-40129 Bologna (Italy); Risaliti, G. [INAF-Osservatorio Astronomico di Arcetri, Largo E. Fermi 5, I-50125 Firenze (Italy)

2012-12-15

We report on the second round of Chandra observations of the 3C snapshot survey developed to observe the complete sample of 3C radio sources with z < 0.3 for 8 ks each. In the first paper, we illustrated the basic data reduction and analysis procedures performed for the 30 sources of the 3C sample observed during Chandra Cycle 9, while here we present the data for the remaining 27 sources observed during Cycle 12. We measured the X-ray intensity of the nuclei and of any radio hot spots and jet features with associated X-ray emission. X-ray fluxes in three energy bands, i.e., soft, medium, and hard, for all the sources analyzed are also reported. For the stronger nuclei, we also applied the standard spectral analysis, which provides the best-fit values of the X-ray spectral index and absorbing column density. In addition, a detailed analysis of bright X-ray nuclei that could be affected by pile-up has been performed. X-ray emission was detected for all the nuclei of the radio sources in our sample except for 3C 319. Among the current sample, there are two compact steep spectrum radio sources, two broad-line radio galaxies, and one wide angle tail radio galaxy, 3C 89, hosted in a cluster of galaxies clearly visible in our Chandra snapshot observation. In addition, we also detected soft X-ray emission arising from the galaxy cluster surrounding 3C 196.1. Finally, X-ray emission from hot spots has been found in three FR II radio sources and, in the case of 3C 459, we also report the detection of X-ray emission associated with the eastern radio lobe as well as X-ray emission cospatial with radio jets in 3C 29 and 3C 402.

A Chandra grating observation of the dusty Wolf-Rayet star WR 48a

Energy Technology Data Exchange (ETDEWEB)

Zhekov, Svetozar A. [Space Research and Technology Institute, Akad. G. Bonchev Str., bl.1, Sofia 1113 (Bulgaria); Gagné, Marc [Department of Geology and Astronomy, West Chester University, West Chester, PA 19383 (United States); Skinner, Stephen L., E-mail: szhekov@space.bas.bg, E-mail: mgagne@wcupa.edu, E-mail: stephen.skinner@colorado.edu [CASA, University of Colorado, Boulder, CO 80309 (United States)

2014-04-10

We present results of a Chandra High-Energy Transmission Grating (HETG) observation of the carbon-rich Wolf-Rayet (WR) star WR 48a. These are the first high-resolution spectra of this object in X-ray. Blueshifted centroids of the spectral lines of ∼ – 360 km s{sup –1} and line widths of 1000-1500 km s{sup –1} (FWHM) were deduced from the analysis of the line profiles of strong emission lines. The forbidden line of Si XIII is strong and not suppressed, indicating that the rarified 10-30 MK plasma forms far from strong sources of far-ultraviolet emission, most likely in a wind collision zone. Global spectral modeling showed that the X-ray spectrum of WR 48a suffered higher absorption in the 2012 October Chandra observation compared with a previous 2008 January XMM-Newton observation. The emission measure of the hot plasma in WR 48a decreased by a factor ∼3 over the same period of time. The most likely physical picture that emerges from the analysis of the available X-ray data is that of colliding stellar winds in a wide binary system with an elliptical orbit. We propose that the unseen secondary star in the system is another WR star or perhaps a luminous blue variable.

Nustar and Chandra insight into the nature of the 3-40 kev nuclear emission in NGC 253

DEFF Research Database (Denmark)

Lehmer, B. D.; Wik, D. R.; Hornschemeier, A. E.

2013-01-01

We present results from three nearly simultaneous Nuclear Spectroscopic Telescope Array ( NuSTAR ) and Chandra monitoring observations between 2012 September 2 and 2012 November 16 of the local star-forming galaxy NGC 253. The 3-40 keV intensity of the inner ~ 20 arcsec ( ~ 400 pc) nuclear region...

Simultaneous NuSTAR/Chandra Observations of The Bursting Pulsar GRO J1744-28 During Its Third Reactivation

DEFF Research Database (Denmark)

Younes, G.; Kouveliotou, C.; Grefenstette, B. W.

2015-01-01

We report on a 10 ks simultaneous Chandra/High Energy Transmission Grating (HETG)-Nuclear Spectroscopic Telescope Array (NuSTAR) observation of the Bursting Pulsar, GRO J1744-28, during its third detected outburst since discovery and after nearly 18 yr of quiescence. The source is detected up to 60...

Analysis of phytochemical variations in dioecious Tinospora cordifolia stems using HPLC/QTOF MS/MS and UPLC/QqQLIT -MS/MS.

Science.gov (United States)

Bajpai, Vikas; Singh, Awantika; Chandra, Preeti; Negi, M P S; Kumar, Nikhil; Kumar, Brijesh

2016-01-01

The stem of dioecious Tinospora cordifolia (Menispermaceae) is a commonly used traditional Ayurvedic medicine in India having several therapeutic properties. To develop and validate LC-MS methods for the identification and simultaneous quantitation of various secondary metabolites and to study metabolomic variations in the stem of male and female plants. Ethanolic extract of stems were analysed by HPLC/ESI-QTOF-MS/MS for rapid screening of bioactive phytochemicals. High resolution MS and MS/MS in positive ESI mode were used for structural investigation of secondary metabolites. An UPLC/ESI-QqQ(LIT) -MS/MS method in MRM mode was developed and validated for the simultaneous quantitation of five bioactive alkaloids. Identification and characterisation of 36 metabolites including alkaloids, sesquiterpenes and phytoecdysteroids were performed using LC-MS and MS/MS techniques. The bioactive alkaloids such as jatrorrhizine, magnoflorine, isocorydine, palmatine and tetrahydropalmatine were successfully quantified in male and female plants. The mean abundances of magnoflorine jatrorrhizine, and oblongine were significantly (P Phytochemicals in the stem of male and female Tinospora cordifolia showed significant qualitative and quantitative variations. LC-MS and MS/MS methods can be used to differentiate between male and female plants based on their chemical profiles and quantities of the marker bioactive alkaloids. This chemical composition difference was also evident during vegetative stage when there were no male and female flowers. Copyright © 2015 John Wiley & Sons, Ltd.

Determination of Glyphosate Levels in Breast Milk Samples from Germany by LC-MS/MS and GC-MS/MS

NARCIS (Netherlands)

Steinborn, Angelika; Alder, Lutz; Michalski, Britta; Zomer, Paul; Bendig, Paul; Martinez, Sandra Aleson; Mol, Hans G.J.; Class, Thomas J.; Costa Pinheiro, Nathalie

2016-01-01

This study describes the validation and application of two independent analytical methods for the determination of glyphosate in breast milk. They are based on liquid chromatography-tandem mass spectrometry (LC-MS/MS) and gas chromatography-tandem mass spectrometry (GC-MS/MS), respectively. For

A cluster in a crowded environment: XMM-Newton and Chandra observations of A3558

Science.gov (United States)

Rossetti, M.; Ghizzardi, S.; Molendi, S.; Finoguenov, A.

2007-03-01

Combining XMM-Newton and Chandra data, we have performed a detailed study of Abell 3558. Our analysis shows that its dynamical history is more complicated than previously thought. We have found some traits typical of cool core clusters (surface brightness peaked at the center, peaked metal abundance profile) and others that are more common in merging clusters, like deviations from spherical symmetry in the thermodynamic quantities of the ICM. This last result has been achieved with a new technique for deriving temperature maps from images. We have also detected a cold front and, with the combined use of XMM-Newton and Chandra, we have characterized its properties, such as the speed and the metal abundance profile across the edge. This cold front is probably due to the sloshing of the core, induced by the perturbation of the gravitational potential associated with a past merger. The hydrodynamic processes related to this perturbation have presumably produced a tail of lower entropy, higher pressure and metal rich ICM, which extends behind the cold front for~500 kpc. The unique characteristics of A3558 are probably due to the very peculiar environment in which it is located: the core of the Shapley supercluster. Appendices A and B are only available in electronic form at http://www.aanda.org

Theonellapeptolide IIIe, a new cyclic peptolide from the New Zealand deep water sponge, Lamellomorpha strongylata.

Science.gov (United States)

Li, S; Dumdei, E J; Blunt, J W; Munro, M H; Robinson, W T; Pannell, L K

1998-06-26

The structure, stereochemistry, and conformation of theonellapeptolide IIIe (1), a new 36-membered ring cyclic peptolide from the New Zealand deep-water sponge Lamellomorpha strongylata, is described. The sequence of the cytotoxic peptolide was determined through a combination of NMR and MS-MS techniques and confirmed by X-ray crystal structure analysis, which, with chiral HPLC, established the absolute stereochemistry.

Finding of pesticides in fashionable fruit juices by LC-MS/MS and GC-MS/MS.

Science.gov (United States)

Tran, Kevin; Eide, David; Nickols, Susan M; Cromer, Michele R; Sabaa-Srur, Armando; Smith, Robert E

2012-10-15

Products labelled as containing extracts from two mushrooms (cordyceps plus reishi) and the juices from açaí, goji, mangosteen, noni, pomegranate, and sea buckthorn have been analysed for 174 different pesticides, using the validated QuEChERS method for sample preparation and electrospray LC-MS/MS in the positive ion mode for analysis. Pesticides were found in 10 of the 21 samples analysed. Most pesticides found were below the tolerance levels (1-6 μg/g, depending on the pesticide), but some were not. This included boscalid, dimethomorph, iprovalicarb, pyridaben, pyrimethanil, and imazalil, for which there is no tolerance reported or zero tolerance in any fruit. However, genuine açaí that was harvested in the state of Pará and lyophilised in Rio de Janeiro had no detectable pesticides, when analysed by both LC-MS/MS and GC-MS/MS, which can detect 213 more pesticides and industrial chemicals. Likewise no pesticides were found in one sample each of cordyceps plus reishi, sea buckthorn and noni. Published by Elsevier Ltd.

The mystery of the "Kite" radio source in Abell 2626: Insights from new Chandra observations

Science.gov (United States)

Ignesti, A.; Gitti, M.; Brunetti, G.; O'Sullivan, E.; Sarazin, C.; Wong, K.

2018-03-01

Context. We present the results of a new Chandra study of the galaxy cluster Abell 2626. The radio emission of the cluster shows a complex system of four symmetric arcs without known correlations with the thermal X-ray emission. The mirror symmetry of the radio arcs toward the center and the presence of two optical cores in the central galaxy suggested that they may be created by pairs of precessing radio jets powered by dual active galactic nuclei (AGNs) inside the core dominant galaxy. However, previous observations failed to observe the second jetted AGN and the spectral trend due to radiative age along the radio arcs, thus challenging this interpretation. Aim. The new Chandra observation had several scientific objectives, including the search for the second AGN that would support the jet precession model. We focus here on the detailed study of the local properties of the thermal and non-thermal emission in the proximity of the radio arcs, in order to obtain further insights into their origin. Methods: We performed a standard data reduction of the Chandra dataset deriving the radial profiles of temperature, density, pressure and cooling time of the intra-cluster medium. We further analyzed the two-dimensional (2D) distribution of the gas temperature, discovering that the south-western junction of the radio arcs surrounds the cool core of the cluster. Results: We studied the X-ray surface brightness and spectral profiles across the junction, finding a cold front spatially coincident with the radio arcs. This may suggest a connection between the sloshing of the thermal gas and the nature of the radio filaments, raising new scenarios for their origin. A tantalizing possibility is that the radio arcs trace the projection of a complex surface connecting the sites where electrons are most efficiently reaccelerated by the turbulence that is generated by the gas sloshing. In this case, diffuse emission embedded by the arcs and with extremely steep spectrum should be

A CHANDRA SURVEY OF THE X-RAY PROPERTIES OF BROAD ABSORPTION LINE RADIO-LOUD QUASARS

International Nuclear Information System (INIS)

Miller, B. P.; Brandt, W. N.; Garmire, G. P.; Gibson, R. R.; Shemmer, O.

2009-01-01

This work presents the results of a Chandra study of 21 broad absorption line (BAL) radio-loud quasars (RLQs). We conducted a Chandra snapshot survey of 12 bright BAL RLQs selected from Sloan Digital Sky Survey Data/Faint Images of the Radio Sky data and possessing a wide range of radio and C IV absorption properties. Optical spectra were obtained nearly contemporaneously with the Hobby-Eberly Telescope; no strong flux or BAL variability was seen between epochs. In addition to the snapshot targets, we include in our sample nine additional BAL RLQs possessing archival Chandra coverage. We compare the properties of (predominantly high-ionization) BAL RLQs to those of non-BAL RLQs as well as to BAL radio-quiet quasars (RQQs) and non-BAL RQQs for context. All 12 snapshots and 8/9 archival BAL RLQs are detected, with observed X-ray luminosities less than those of non-BAL RLQs having comparable optical/UV luminosities by typical factors of 4.1-8.5. (BAL RLQs are also X-ray weak by typical factors of 2.0-4.5 relative to non-BAL RLQs having both comparable optical/UV and radio luminosities.) However, BAL RLQs are not as X-ray weak relative to non-BAL RLQs as are BAL RQQs relative to non-BAL RQQs. While some BAL RLQs have harder X-ray spectra than typical non-BAL RLQs, some have hardness ratios consistent with those of non-BAL RLQs, and there does not appear to be a correlation between X-ray weakness and spectral hardness, in contrast to the situation for BAL RQQs. RLQs are expected to have X-ray continuum contributions from both accretion-disk corona and small-scale jet emission. While the entire X-ray continuum in BAL RLQs cannot be obscured to the same degree as in BAL RQQs, we calculate that the jet is likely partially covered in many BAL RLQs. We comment briefly on implications for geometries and source ages in BAL RLQs.

Chandra Cluster Cosmology Project. II. Samples and X-Ray Data Reduction

DEFF Research Database (Denmark)

Vikhlinin, A.; Burenin, R. A.; Ebeling, H.

2009-01-01

We discuss the measurements of the galaxy cluster mass functions at z ≈ 0.05 and z ≈ 0.5 using high-quality Chandra observations of samples derived from the ROSAT PSPC All-Sky and 400 deg2 surveys. We provide a full reference for the data analysis procedures, present updated calibration of relati...... at a fixed mass threshold, e.g., by a factor of 5.0 ± 1.2 at M 500 = 2.5 × 1014 h –1 M sun between z = 0 and 0.5. This evolution reflects the growth of density perturbations, and can be used for the cosmological constraints complementing those from the distance-redshift relation....

Pediatric MS

Science.gov (United States)

... Pediatric MS Share this page Facebook Twitter Email Pediatric MS Pediatric MS Pediatric MS Support Pediatric Providers ... system through the Pediatric MS Support Group . Treating pediatric MS In 2018 the U.S. Food and Drug ...

Neuronal pathology in deep grey matter structures: a multimodal imaging analysis combining PET and MRI

Energy Technology Data Exchange (ETDEWEB)

Bosque-Freeman, L.; Leroy, C.; Galanaud, D.; Sureau, F.; Assouad, R.; Tourbah, A.; Papeix, C.; Comtat, C.; Trebossen, R.; Lubetzki, C.; Delforge, J.; Bottlaender, M.; Stankoff, B. [Serv. Hosp. Frederic Joliot, Orsay (France)

2009-07-01

Objective: To assess neuronal damage in deep gray matter structures by positron emission tomography (PET) using [{sup 11}C]-flumazenil (FMZ), a specific central benzodiazepine receptor antagonist, and [{sup 18}F]-fluorodeoxyglucose (FDG), which reflects neuronal metabolism. To compare results obtained by PET and those with multimodal magnetic resonance imaging (MRI). Background: It is now accepted that neuronal injury plays a crucial role in the occurrence and progression of neurological disability in multiple sclerosis (MS). To date, available MRI techniques do not specifically assess neuronal damage, but early abnormalities, such as iron deposition or atrophy, have been described in deep gray matter structures. Whether those MRI modifications correspond to neuronal damage remains to be further investigated. Materials and methods: Nine healthy volunteers were compared to 10 progressive and 9 relapsing remitting (RR) MS patients. Each subject performed two PET examinations with [{sup 11}C]-FMZ and [{sup 18}F]-FDG, on a high resolution research tomograph dedicated to brain imaging (Siemens Medical Solution, spatial resolution of 2.5 mm). Deep gray matter regions were manually segmented on T1-weighted MR images with the mutual information algorithm (www.brainvisa.info), and co-registered with PET images. A multimodal MRI including T1 pre and post gadolinium, T2-proton density sequences, magnetization transfer, diffusion tensor, and protonic spectroscopy was also performed for each subject. Results: On PET with [{sup 11}C]-FMZ, there was a pronounced decrease in receptor density for RR patients in all deep gray matter structures investigated, whereas the density was unchanged or even increased in the same regions for progressive patients. Whether the different patterns between RR and progressive patients reflect distinct pathogenic mechanisms is currently investigated by comparing PET and multimodal MRI results. Conclusion: Combination of PET and multimodal MR imaging

Simultaneous NuSTAR/Chandra Observations of the Bursting Pulsar GRO J1744-28 During its Third Reactivation

Science.gov (United States)

Younes, G.; Kouveliotou, C.; Grefenstette, B. W.; Tomsick, J. A.; Tennant, A.; Finger, M. H.; Furst, F.; Pottschmidt, K.; Bhalerao, V.; Boggs, S. E.;

SIMULTANEOUS NuSTAR/CHANDRA OBSERVATIONS OF THE BURSTING PULSAR GRO J1744-28 DURING ITS THIRD REACTIVATION

Energy Technology Data Exchange (ETDEWEB)

Younes, G.; Finger, M. H. [Universities Space Research Association, 6767 Old Madison Pike, Suite 450, Huntsville, AL 35806 (United States); Kouveliotou, C.; Tennant, A. [Astrophysics Office, ZP 12, NASA-Marshall Space Flight Center, Huntsville, AL 35812 (United States); Grefenstette, B. W.; Fürst, F. [Cahill Center for Astrophysics, 1216 East California Boulevard, California Institute of Technology, Pasadena, CA 91125 (United States); Tomsick, J. A.; Boggs, S. E.; Craig, W. W. [Space Sciences Laboratory, 7 Gauss Way, University of California, Berkeley, CA 94720-7450 (United States); Pottschmidt, K. [Center for Space Science and Technology, University of Maryland Baltimore County, Baltimore, MD 21250 (United States); Bhalerao, V. [Inter-University Center for Astronomy and Astrophysics, Post Bag 4, Ganeshkhind, Pune 411007 (India); Boirin, L. [Observatoire Astronomique de Strasbourg, 11 Rue de l' Université, F-67000 Strasbourg (France); Chakrabarty, D. [Kavli Institute for Astrophysics and Space Research, Massachusetts Institute of Technology, Cambridge, MA 02139 (United States); Christensen, F. E. [DTU Space, National Space Institute, Technical University of Denmark, Elektrovej 327, DK-2800 Lyngby (Denmark); Degenaar, N. [Department of Astronomy, University of Michigan, 1085 South University Avenue, Ann Arbor, MI 48109 (United States); Fabian, A. C. [Institute of Astronomy, Madingley Road, Cambridge CB3 0HA (United Kingdom); Gandhi, P. [Department of Physics, Durham University, South Road, Durham DH1 3LE (United Kingdom); Göğüş, E. [Sabancı University, Orhanlı-Tuzla, İstanbul 34956 (Turkey); and others

2015-05-01

We report on a 10 ks simultaneous Chandra/High Energy Transmission Grating (HETG)–Nuclear Spectroscopic Telescope Array (NuSTAR) observation of the Bursting Pulsar, GRO J1744-28, during its third detected outburst since discovery and after nearly 18 yr of quiescence. The source is detected up to 60 keV with an Eddington persistent flux level. Seven bursts, followed by dips, are seen with Chandra, three of which are also detected with NuSTAR. Timing analysis reveals a slight increase in the persistent emission pulsed fraction with energy (from 10% to 15%) up to 10 keV, above which it remains constant. The 0.5–70 keV spectra of the persistent and dip emission are the same within errors and well described by a blackbody (BB), a power-law (PL) with an exponential rolloff, a 10 keV feature, and a 6.7 keV emission feature, all modified by neutral absorption. Assuming that the BB emission originates in an accretion disk, we estimate its inner (magnetospheric) radius to be about 4 × 10{sup 7} cm, which translates to a surface dipole field B ≈ 9 × 10{sup 10} G. The Chandra/HETG spectrum resolves the 6.7 keV feature into (quasi-)neutral and highly ionized Fe xxv and Fe xxvi emission lines. XSTAR modeling shows these lines to also emanate from a truncated accretion disk. The burst spectra, with a peak flux more than an order of magnitude higher than Eddington, are well fit with a PL with an exponential rolloff and a 10 keV feature, with similar fit values compared to the persistent and dip spectra. The burst spectra lack a thermal component and any Fe features. Anisotropic (beamed) burst emission would explain both the lack of the BB and any Fe components.

Cognitive Implications of Deep Gray Matter Iron in Multiple Sclerosis.

Science.gov (United States)

Fujiwara, E; Kmech, J A; Cobzas, D; Sun, H; Seres, P; Blevins, G; Wilman, A H

2017-05-01

Deep gray matter iron accumulation is increasingly recognized in association with multiple sclerosis and can be measured in vivo with MR imaging. The cognitive implications of this pathology are not well-understood, especially vis-à-vis deep gray matter atrophy. Our aim was to investigate the relationships between cognition and deep gray matter iron in MS by using 2 MR imaging-based iron-susceptibility measures. Forty patients with multiple sclerosis (relapsing-remitting, n = 16; progressive, n = 24) and 27 healthy controls were imaged at 4.7T by using the transverse relaxation rate and quantitative susceptibility mapping. The transverse relaxation rate and quantitative susceptibility mapping values and volumes (atrophy) of the caudate, putamen, globus pallidus, and thalamus were determined by multiatlas segmentation. Cognition was assessed with the Brief Repeatable Battery of Neuropsychological Tests. Relationships between cognition and deep gray matter iron were examined by hierarchic regressions. Compared with controls, patients showed reduced memory ( P processing speed ( P = .02) and smaller putamen ( P deep gray matter iron accumulation in the current multiple sclerosis cohort. Atrophy and iron accumulation in deep gray matter both have negative but separable relationships to cognition in multiple sclerosis. © 2017 by American Journal of Neuroradiology.

THE MULTIWAVELENGTH SURVEY BY YALE-CHILE (MUSYC): DEEP MEDIUM-BAND OPTICAL IMAGING AND HIGH-QUALITY 32-BAND PHOTOMETRIC REDSHIFTS IN THE ECDF-S

International Nuclear Information System (INIS)

Cardamone, Carolin N.; Van Dokkum, Pieter G.; Urry, C. Megan; Brammer, Gabriel; Taniguchi, Yoshi; Gawiser, Eric; Bond, Nicholas; Taylor, Edward; Damen, Maaike; Treister, Ezequiel; Cobb, Bethany E.; Schawinski, Kevin; Lira, Paulina; Murayama, Takashi; Saito, Tomoki; Sumikawa, Kentaro

2010-01-01

We present deep optical 18-medium-band photometry from the Subaru telescope over the ∼30' x 30' Extended Chandra Deep Field-South, as part of the Multiwavelength Survey by Yale-Chile (MUSYC). This field has a wealth of ground- and space-based ancillary data, and contains the GOODS-South field and the Hubble Ultra Deep Field. We combine the Subaru imaging with existing UBVRIzJHK and Spitzer IRAC images to create a uniform catalog. Detecting sources in the MUSYC 'BVR' image we find ∼40,000 galaxies with R AB 3.5. For 0.1 < z < 1.2, we find a 1σ scatter in Δz/(1 + z) of 0.007, similar to results obtained with a similar filter set in the COSMOS field. As a demonstration of the data quality, we show that the red sequence and blue cloud can be cleanly identified in rest-frame color-magnitude diagrams at 0.1 < z < 1.2. We find that ∼20% of the red sequence galaxies show evidence of dust emission at longer rest-frame wavelengths. The reduced images, photometric catalog, and photometric redshifts are provided through the public MUSYC Web site.

Intraday X-Ray Variability of QSOs/AGN Using the Chandra Archives

Science.gov (United States)

Tartamella, C.; Busche, J.

2005-05-01

X-ray variability is a common characteristic of Active Galactic Nuclei (AGN), and it can be used to probe the nuclear region at short time scales. Quantitative analysis of this variability has been difficult due to low signal-to-noise ratios and short time baselines, but serendipitous Chandra data acquired within the last six years have opened the door to such analysis. Cross-correlation of the Chandra archives with QSO/AGN catalogs on NASA's HEASARC website (e.g. Veron, Sloan) yields a sample of 50+ objects that satisfy the following criteria: absolute magnitude M≤ -22.5, proper time baselines greater than 2 hours, and count rates leading to 10% error bars for 8+ flux points on the light curve. The sample includes a range of red-shifts, magnitudes, and type (e.g. radio loud, radio quiet), and hence may yield empirical clues about luminosity or evolutionary trends. As a beginning of such analysis, we present 11 light curves for 9 objects for which the exposure time was greater than 10 hours. The variability was analyzed using three different statistical methods. The Kolmogorov-Smirnov (KS) test proved to be impractical because of the unavoidably small number of data points and the simplistic nature of the test. A χ2 test indicated in most cases that there were significant departures from constant brightness (as expected). Autocorrelation plots were also generated for each light curve. With more work and a larger sample size, these plots can be used to identify any trends in the lightcurve such as whether the variability is stochastic or periodic in nature. This test was useful even with the small number of datapoints available. In future work, more sophisticated analyses based on Fourier series, power density spectra, or wavelets are likely to yield more meaningful and useful results.

Deep gray matter demyelination detected by magnetization transfer ratio in the cuprizone model.

Directory of Open Access Journals (Sweden)

Sveinung Fjær

Full Text Available In multiple sclerosis (MS, the correlation between lesion load on conventional magnetic resonance imaging (MRI and clinical disability is weak. This clinico-radiological paradox might partly be due to the low sensitivity of conventional MRI to detect gray matter demyelination. Magnetization transfer ratio (MTR has previously been shown to detect white matter demyelination in mice. In this study, we investigated whether MTR can detect gray matter demyelination in cuprizone exposed mice. A total of 54 female C57BL/6 mice were split into one control group ( and eight cuprizone exposed groups ([Formula: see text]. The mice were exposed to [Formula: see text] (w/w cuprizone for up to six weeks. MTR images were obtained at a 7 Tesla Bruker MR-scanner before cuprizone exposure, weekly for six weeks during cuprizone exposure, and once two weeks after termination of cuprizone exposure. Immunohistochemistry staining for myelin (anti-Proteolopid Protein and oligodendrocytes (anti-Neurite Outgrowth Inhibitor Protein A was obtained after each weekly scanning. Rates of MTR change and correlations between MTR values and histological findings were calculated in five brain regions. In the corpus callosum and the deep gray matter a significant rate of MTR value decrease was found, [Formula: see text] per week ([Formula: see text] and [Formula: see text] per week ([Formula: see text] respectively. The MTR values correlated to myelin loss as evaluated by immunohistochemistry (Corpus callosum: [Formula: see text]. Deep gray matter: [Formula: see text], but did not correlate to oligodendrocyte density. Significant results were not found in the cerebellum, the olfactory bulb or the cerebral cortex. This study shows that MTR can be used to detect demyelination in the deep gray matter, which is of particular interest for imaging of patients with MS, as deep gray matter demyelination is common in MS, and is not easily detected on conventional clinical MRI.

Chandra, NuSTAR and NICER Observations of MAXI J1535-571

Science.gov (United States)

Neilsen, Joseph; Cackett, Ed; Fabian, Andy; Gendreau, Keith C.; Miller, Jon M.; Pasham, Dheeraj; Remillard, Ron; Steiner, Jack; Uttley, Phil

2018-01-01

In September 2017, MAXI detected an outburst of a previously-unknown transient, MAXI J1535-571. Subsequent radio and X-ray monitoring indicated that the source is a strong black hole candidate. We began a series of monitoring observations with Chandra HETGS, NuSTAR, and NICER to track the evolution of the outburst. Together, these three observatories represent an incredible opportunity to study the geometry of the accretion flow (via continuum spectroscopy), its variation with accretion state (via spectral variability), and any associated outflows or mass ejections (via line spectroscopy). We will present our analysis of this bright outburst and discuss the physics of accretion and ejection in this new black hole candidate.

A CHANDRA OBSERVATION OF SNR 0540 - 697

International Nuclear Information System (INIS)

Seward, F. D.; Williams, R. M.; Chu, Y.-H.; Gruendl, R. A.; Dickel, J. R.

2010-01-01

This paper describes a Chandra observation of SNR 0540 - 697 within the H II complex N159 in the Large Magellanic Cloud (LMC). Scattering from the nearby bright source LMC X-1, which obscures the western edge of the remnant, has been removed. Larger than previously believed, the 2.'0 x 2.'8 remnant is defined by optical filaments and two lobes of X-ray emission. A band of intervening material absorbs X-rays from the central part of the remnant. The N Lobe of the remnant is relatively bright and well defined, while emission from the S Lobe is much weaker. There is structure within the N Lobe but no clear X-ray emission from an outer shell indicating a shock in the interstellar medium. The X-ray spectrum is thermal with emission lines from Fe, Mg, and Si. The observed temperature and luminosity of the hot gas are 0.6 keV and 6 x 10 35 erg s -1 , respectively. These are consistent with characteristics expected for older remnants. There is also diffuse thermal X-ray emission north of N159 extending into N160, evidence for a larger remnant or bubble.

Temporal variation of gravity field prior to the Ludian Ms6.5 and Kangding Ms6.3 earthquakes

Directory of Open Access Journals (Sweden)

Hongtao Hao

2015-11-01

Full Text Available Using mobile gravity data from the central area of Sichuan and Yunnan Provinces, the relationship between gravity variation and earthquakes was studied based on the Ludian Ms6.5 earthquake that occurred on August 3rd, 2014, and the Kangding Ms6.3 earthquake that occurred on November 22nd, 2014; the mechanism of gravity variation was also explored. The results are as follows: (1 Prior to both earthquakes, gravity variation exhibited similar characteristics as those observed before both the Tangshan and Wenchuan earthquakes, in which typical precursor anomalies were positive gravity variation near the epicenter and the occurrence of a high-gravity-gradient zone across the epicenter prior to the earthquake. (2 A relatively accurate prediction of the occurrence locations of the two earthquakes was made by the Gravity Network Center of China (GNCC based on these precursor anomalies. In the gravity study report on the 2014 earthquake trends submitted at the end of 2013, the Daofu-Shimian section at the junction of the Xianshuihe and Longmenshan fault zones was noted as an earthquake-risk region with a predicted magnitude of 6.5, which covered the epicenter of the Kangding Ms6.3 earthquake. In another report on earthquake trends in southwestern China submitted in mid-2014, the Lianfeng, Zhaotong fault zone was also classified as an earthquake-risk region with a magnitude of 6.0, and the central area of this region basically overlapped with the epicenter of the Ludian Ms6.5 earthquake. (3 The gravity variation characteristics are reasonably consistent with crustal movements, and deep material migration is likely the primary cause of gravity variation.

Dansyl-peptides matrix-assisted laser desorption/ionization mass spectrometric (MALDI-MS) and tandem mass spectrometric (MS/MS) features improve the liquid chromatography/MALDI-MS/MS analysis of the proteome.

Science.gov (United States)

Chiappetta, Giovanni; Ndiaye, Sega; Demey, Emmanuelle; Haddad, Iman; Marino, Gennaro; Amoresano, Angela; Vinh, Joëlle

2010-10-30

Peptide tagging is a useful tool to improve matrix-assisted laser desorption/ionization tandem mass spectrometric (MALDI-MS/MS) analysis. We present a new application of the use of the dansyl chloride (DNS-Cl). DNS-Cl is a specific primary amine reagent widely used in protein biochemistry. It adds a fluorescent dimethylaminonaphthalene moiety to the molecule. The evaluation of MALDI-MS and MS/MS analyses of dansylated peptides shows that dansylation raises the ionization efficiency of the most hydrophilic species compared with the most hydrophobic ones. Consequently, higher Mascot scores and protein sequence coverage are obtained by combining MS and MS/MS data of native and tagged samples. The N-terminal DNS-Cl sulfonation improves the peptide fragmentation and promotes the generation of b-fragments allowing better peptide sequencing. In addition, we set up a labeling protocol based on the microwave chemistry. Peptide dansylation proved to be a rapid and cheap method to improve the performance of liquid chromatography (LC)/MALDI-MS/MS analysis at the proteomic scale in terms of peptide detection and sequence coverage. Copyright © 2010 John Wiley & Sons, Ltd.

Op. No A4495 Columbia, STS-93 Chandra - Breakfast, Suiting, and Walkout

Science.gov (United States)

1999-01-01

The primary objective of the STS-93 mission was to deploy the Advanced X-ray Astrophysical Facility, which had been renamed the Chandra X-ray Observatory in honor of the late Indian-American Nobel Laureate Subrahmanyan Chandrasekhar. The mission was launched at 12:31 on July 23, 1999 onboard the space shuttle Columbia. The mission was led by Commander Eileen Collins. The crew was Pilot Jeff Ashby and Mission Specialists Cady Coleman, Steve Hawley and Michel Tognini from the Centre National d'Etudes Spatiales (CNES). This videotape shows the astronauts after breakfast getting into spacesuits, walking out to board the bus, and boarding the bus prior to launch.

THE NATURE OF THE BRIGHT ULX X-2 IN NGC 3921: A CHANDRA POSITION AND HST CANDIDATE COUNTERPART

Energy Technology Data Exchange (ETDEWEB)

Jonker, P. G.; Heida, M.; Torres, M. A. P.; Ratti, E. M. [SRON, Netherlands Institute for Space Research, Sorbonnelaan 2, 3584 CA Utrecht (Netherlands); Miller-Jones, J. C. A. [International Centre for Radio Astronomy Research, Curtin University, GPO Box U1987, Perth, WA 6845 (Australia); Fabian, A. C.; Walton, D. J. [Institute of Astronomy, Madingley Road, Cambridge CB3 0HA (United Kingdom); Miniutti, G. [Centro de Astrobiologia (CSIC-INTA), Departamento de Astrofisica, ESA, P.O. Box 78, E-28691 Villanueva de la Canada, Madrid (Spain); Roberts, T. P., E-mail: p.jonker@sron.nl [Department of Physics, Durham University, South Road, Durham DH1 3LE (United Kingdom)

2012-10-10

We report on Chandra observations of the bright ultraluminous X-ray (ULX) source in NGC 3921. Previous XMM-Newton observations reported in the literature show the presence of a bright ULX at a 0.5-10 keV luminosity of 2 Multiplication-Sign 10{sup 40} erg s{sup -1}. Our Chandra observation finds the source at a lower luminosity of Almost-Equal-To 8 Multiplication-Sign 10{sup 39} erg s{sup -1}; furthermore, we provide a Chandra position of the ULX accurate to 0.''7 at 90% confidence. The X-ray variability makes it unlikely that the high luminosity is caused by several separate X-ray sources. In three epochs of archival Hubble Space Telescope observations, we find a candidate counterpart to the ULX. There is direct evidence for variability between the two epochs of WFPC2 F814W observations with the observation obtained in 2000 showing a brighter source. Furthermore, converting the 1994 F336W and 2000 F300W WFPC2 and the 2010 F336W WFC3 observations to the Johnson U-band filter assuming a spectral type of O7I, we find evidence for a brightening of the U-band light in 2000. Using the higher resolution WFC3 observations, we resolve the candidate counterpart into two sources of similar color. We discuss the nature of the ULX and the probable association with the optical counterpart(s). Finally, we investigate a potential new explanation for some (bright) ULXs as the decaying stages of flares caused by the tidal disruption of a star by a recoiled supermassive black hole. However, we find that there should be at most only one of such systems within z = 0.08.

A Preliminary Assessment of a Deep Borehole disposal of Spent Fuels

International Nuclear Information System (INIS)

Lee, Younmyoung; Jeon, Jongtae

2014-01-01

Deep borehole disposal (DBD) of such radioactive waste as spent nuclear fuels (SFs) and other waste forms has been investigating mainly at Sandia National Labs for the US DOE as an alternative option. DBD can give advantages over less deep geological disposal since the disposal of wastes at a great depth where a low degree of permeability in the potentially steady rock condition will be beneficial for nuclide movement. Groundwater in the deep basement rock can even have salinity and less chance to mix with groundwater above. The DBD concept is quite straightforward and even simple: Waste canisters are simply emplaced in the lower 2 km part of the borehole down to 5 km deep. Through this study, a conceptual DBD is assessed for a similar case as the US DOE's approach, in which 400 SF canisters are to be emplaced at a deep bottom between 3km and 5km depths, upon which an additional 1km-thick compacted bentonite is overbuffered, and the remaining upper part of the borehole is backfilled again with a mixture of crushed rock and bentonite. Then, the total 5km-deep borehole has three zones: a disposal zone at the bottom 2km, a buffer zone at the next 1km, and backfill zone at the rest top 2km, as illustrated conceptually in Fig. 1. To demonstrate the feasibility in view of long-term radiological safety, a rough model for a safety assessment of this conceptual deep borehole repository system, providing detailed models for nuclide transport in and around the geosphere and biosphere under normal nuclide release scenarios that can occur after a closure of the repository, has been developed using GoldSim. A simple preliminary result in terms of the dose exposure rate from a safety assessment of the DBD is also presented and compared to the case of direct disposal of SFs in a KBS-3V vertical type repository, carried out in previous studies. For different types and shapes of repositories at each different depth, direct comparison between a DBD and a KBS-3 type disposal of

A Preliminary Assessment of a Deep Borehole disposal of Spent Fuels

Energy Technology Data Exchange (ETDEWEB)

Lee, Younmyoung; Jeon, Jongtae [Korea Atomic Energy Research Institute, Daejeon (Korea, Republic of)

2014-05-15

Deep borehole disposal (DBD) of such radioactive waste as spent nuclear fuels (SFs) and other waste forms has been investigating mainly at Sandia National Labs for the US DOE as an alternative option. DBD can give advantages over less deep geological disposal since the disposal of wastes at a great depth where a low degree of permeability in the potentially steady rock condition will be beneficial for nuclide movement. Groundwater in the deep basement rock can even have salinity and less chance to mix with groundwater above. The DBD concept is quite straightforward and even simple: Waste canisters are simply emplaced in the lower 2 km part of the borehole down to 5 km deep. Through this study, a conceptual DBD is assessed for a similar case as the US DOE's approach, in which 400 SF canisters are to be emplaced at a deep bottom between 3km and 5km depths, upon which an additional 1km-thick compacted bentonite is overbuffered, and the remaining upper part of the borehole is backfilled again with a mixture of crushed rock and bentonite. Then, the total 5km-deep borehole has three zones: a disposal zone at the bottom 2km, a buffer zone at the next 1km, and backfill zone at the rest top 2km, as illustrated conceptually in Fig. 1. To demonstrate the feasibility in view of long-term radiological safety, a rough model for a safety assessment of this conceptual deep borehole repository system, providing detailed models for nuclide transport in and around the geosphere and biosphere under normal nuclide release scenarios that can occur after a closure of the repository, has been developed using GoldSim. A simple preliminary result in terms of the dose exposure rate from a safety assessment of the DBD is also presented and compared to the case of direct disposal of SFs in a KBS-3V vertical type repository, carried out in previous studies. For different types and shapes of repositories at each different depth, direct comparison between a DBD and a KBS-3 type disposal of

MALDI-TOF MS/MS measurements of PMMA

NARCIS (Netherlands)

Becer, C.R.; Baumgaertel, A.; Gottschaldt, M.; Schubert, U.S.

2008-01-01

The polymer poly(Me methacrylate) (PMMA) was analyzed using the matrix-assisted laser desorption ionization time-of-flight mass spectrometry (MALDI-TOF MS) technique. The MALDI-TOF MS app. was coupled with a collision-induced dissocn. (CID) unit. The performance of the MALDI-TOF/TOF MS method in

VLBA AND CHANDRA OBSERVATIONS OF JETS IN FRI RADIO GALAXIES: CONSTRAINTS ON JET EVOLUTION

International Nuclear Information System (INIS)

Kharb, P.; O'Dea, C. P.; Tilak, A.; Baum, S. A.; Haynes, E.; Noel-Storr, J.; Fallon, C.; Christiansen, K.

2012-01-01

We present here the results from new Very Long Baseline Array (VLBA) observations at 1.6 and 5 GHz of 19 galaxies of a complete sample of 21 Uppasala General Catalog (UGC) Fanaroff-Riley type I (FRI) radio galaxies. New Chandra data of two sources, viz., UGC 00408 and UGC 08433, are combined with the Chandra archival data of 13 sources. The 5 GHz observations of 10 'core-jet' sources are polarization-sensitive, while the 1.6 GHz observations constitute second-epoch total intensity observations of nine 'core-only' sources. Polarized emission is detected in the jets of seven sources at 5 GHz, but the cores are essentially unpolarized, except in M87. Polarization is detected at the jet edges in several sources, and the inferred magnetic field is primarily aligned with the jet direction. This could be indicative of magnetic field 'shearing' due to jet-medium interaction, or the presence of helical magnetic fields. The jet peak intensity I ν falls with distance d from the core, following the relation, I ν ∝d a , where a is typically ∼ – 1.5. Assuming that adiabatic expansion losses are primarily responsible for the jet intensity 'dimming,' two limiting cases are considered: (1) the jet has a constant speed on parsec scales and is expanding gradually such that the jet radius r∝d 0 .4 ; this expansion is, however, unobservable in the laterally unresolved jets at 5 GHz, and (2) the jet is cylindrical and is accelerating on parsec scales. Accelerating parsec-scale jets are consistent with the phenomenon of 'magnetic driving' in Poynting-flux-dominated jets. While slow jet expansion as predicted by case (1) is indeed observed in a few sources from the literature that are resolved laterally, on scales of tens or hundreds of parsecs, case (2) cannot be ruled out in the present data, provided the jets become conical on scales larger than those probed by VLBA. Chandra observations of 15 UGC FRIs detect X-ray jets in 9 of them. The high frequency of occurrence of X

Spatial Vertical Directionality and Correlation of Low-Frequency Ambient Noise in Deep Ocean Direct-Arrival Zones

Directory of Open Access Journals (Sweden)

Qiulong Yang

2018-01-01

Full Text Available Wind-driven and distant shipping noise sources contribute to the total noise field in the deep ocean direct-arrival zones. Wind-driven and distant shipping noise sources may significantly and simultaneously affect the spatial characteristics of the total noise field to some extent. In this work, a ray approach and parabolic equation solution method were jointly utilized to model the low-frequency ambient noise field in a range-dependent deep ocean environment by considering their calculation accuracy and efficiency in near-field wind-driven and far-field distant shipping noise fields. The reanalysis databases of National Center of Environment Prediction (NCEP and Volunteer Observation System (VOS were used to model the ambient noise source intensity and distribution. Spatial vertical directionality and correlation were analyzed in three scenarios that correspond to three wind speed conditions. The noise field was dominated by distant shipping noise sources when the wind speed was less than 3 m/s, and then the spatial vertical directionality and vertical correlation of the total noise field were nearly consistent with those of distant shipping noise field. The total noise field was completely dominated by near field wind generated noise sources when the wind speed was greater than 12 m/s at 150 Hz, and then the spatial vertical correlation coefficient and directionality pattern of the total noise field was approximately consistent with that of the wind-driven noise field. The spatial characteristics of the total noise field for wind speeds between 3 m/s and 12 m/s were the weighted results of wind-driven and distant shipping noise fields. Furthermore, the spatial characteristics of low-frequency ambient noise field were compared with the classical Cron/Sherman deep water noise field coherence function. Simulation results with the described modeling method showed good agreement with the experimental measurement results based on the vertical line

Spatial Vertical Directionality and Correlation of Low-Frequency Ambient Noise in Deep Ocean Direct-Arrival Zones

Science.gov (United States)

Yang, Qiulong; Yang, Kunde; Cao, Ran; Duan, Shunli

2018-01-01

Wind-driven and distant shipping noise sources contribute to the total noise field in the deep ocean direct-arrival zones. Wind-driven and distant shipping noise sources may significantly and simultaneously affect the spatial characteristics of the total noise field to some extent. In this work, a ray approach and parabolic equation solution method were jointly utilized to model the low-frequency ambient noise field in a range-dependent deep ocean environment by considering their calculation accuracy and efficiency in near-field wind-driven and far-field distant shipping noise fields. The reanalysis databases of National Center of Environment Prediction (NCEP) and Volunteer Observation System (VOS) were used to model the ambient noise source intensity and distribution. Spatial vertical directionality and correlation were analyzed in three scenarios that correspond to three wind speed conditions. The noise field was dominated by distant shipping noise sources when the wind speed was less than 3 m/s, and then the spatial vertical directionality and vertical correlation of the total noise field were nearly consistent with those of distant shipping noise field. The total noise field was completely dominated by near field wind generated noise sources when the wind speed was greater than 12 m/s at 150 Hz, and then the spatial vertical correlation coefficient and directionality pattern of the total noise field was approximately consistent with that of the wind-driven noise field. The spatial characteristics of the total noise field for wind speeds between 3 m/s and 12 m/s were the weighted results of wind-driven and distant shipping noise fields. Furthermore, the spatial characteristics of low-frequency ambient noise field were compared with the classical Cron/Sherman deep water noise field coherence function. Simulation results with the described modeling method showed good agreement with the experimental measurement results based on the vertical line array deployed near

PIXE and PIGE analysis of pre-colonial pottery from Patanal - MS, Brazil

International Nuclear Information System (INIS)

Felicissimo, M.P.; Rodrigues-Filho, U.P.; Peixoto, J.L.; Barbosa, M.S.; Demortier, G.; Pireaux, J.J.

2006-01-01

PIXE and PIGE were applied to investigate the pottery from two archaeological sites located near the Brazil-Bolivia border in Pantanal, an area of natural preservation. The region was inhabited by ancient Amerindian tribes long before the Latin America colonization period and a deep understanding of their environment, cultural attributes and interconnections can only be achieved based on the study of archaeological findings. Multivariate statistical procedures were used to determine similarities and correlations between the analyzed samples and to indicate possible sources of raw material provenience. The results showed that traces of Cr, Cu and Ti and Na/Si and Mg/Si counting ratios were important to distinguish sherds from the archaeological sites MS-CP-71 and MS-CP-61. (author)

INVESTIGATING THE OPTICAL COUNTERPART CANDIDATES OF FOUR INTEGRAL SOURCES LOCALIZED WITH CHANDRA

International Nuclear Information System (INIS)

Özbey Arabacı, Mehtap; Kalemci, Emrah; Tomsick, John A.; Bodaghee, Arash; Halpern, Jules; Chaty, Sylvain; Rodriguez, Jerome; Rahoui, Farid

2012-01-01

We report on the optical spectroscopic follow-up observations of the candidate counterparts to four INTEGRAL sources: IGR J04069+5042, IGR J06552–1146, IGR J21188+4901, and IGR J22014+6034. The candidate counterparts were determined with Chandra, and the optical observations were performed with 1.5 m RTT-150 telescope (TÜBİTAK National Observatory, Antalya, Turkey) and 2.4 m Hiltner Telescope (MDM Observatory, Kitt Peak, Arizona). Our spectroscopic results show that one of the two candidates of IGR J04069+5042 and the one observed for IGR J06552–1146 could be active late-type stars in RS CVn systems. However, according to the likelihood analysis based on Chandra and INTEGRAL, two optically weaker sources in the INTEGRAL error circle of IGR J06552–1146 have higher probabilities to be the actual counterpart. The candidate counterparts of IGR J21188+4901 are classified as an active M-type star and a late-type star. Among the optical spectra of four candidates of IGR J22014+6034, two show Hα emission lines, one is a late-type star, and the other is an M type. The likelihood analysis favors a candidate with no distinguishing features in the optical spectrum. Two of the candidates classified as M-type dwarfs, are similar to some IGR candidates claimed to be symbiotic stars. However, some of the prominent features of symbiotic systems are missing in our spectra, and their NIR colors are not consistent with those expected for giants. We consider the IR colors of all IGR candidates claimed to be symbiotic systems and find that low-resolution optical spectrum may not be enough for conclusive identification.

Improved differentiation between MS and vascular brain lesions using FLAIR* at 7 Tesla

Energy Technology Data Exchange (ETDEWEB)

Kilsdonk, Iris D.; Wattjes, Mike P.; Lopez-Soriano, Alexandra; Jong, Marcus C. de; Graaf, Wolter L. de; Conijn, Mandy M.A.; Barkhof, Frederik [VU University Medical Center, Department of Radiology, De Boelelaan 1118, HZ, Amsterdam (Netherlands); Kuijer, Joost P.A. [VU University Medical Center, Department of Physics and Medical Technology, Amsterdam (Netherlands); Polman, Chris H. [VU University Medical Center, Department of Neurology, Amsterdam (Netherlands); Luijten, Peter R. [University Medical Center, Department of Radiology, Utrecht (Netherlands); Geurts, Jeroen J.G. [VU University, Department of Anatomy and Neurosciences, Amsterdam (Netherlands); Geerlings, Mirjam I. [University Medical Center, Julius Center for Health Sciences and Primary Care, Utrecht (Netherlands)

2014-04-15

To investigate whether a new magnetic resonance image (MRI) technique called T2*-weighted fluid attenuation inversion recovery (FLAIR*) can differentiate between multiple sclerosis (MS) and vascular brain lesions, at 7 Tesla (T). We examined 16 MS patients and 16 age-matched patients with (risk factors for) vascular disease. 3D-FLAIR and T2*-weighted images were combined into FLAIR* images. Lesion type and intensity, perivascular orientation and presence of a hypointense rim were analysed. In total, 433 cerebral lesions were detected in MS patients versus 86 lesions in vascular patients. Lesions in MS patients were significantly more often orientated in a perivascular manner: 74 % vs. 47 % (P < 0.001). Ten MS lesions (2.3 %) were surrounded by a hypointense rim on FLAIR*, and 24 MS lesions (5.5 %) were hypointense on T2*. No lesions in vascular patients showed any rim or hypointensity. Specificity of differentiating MS from vascular lesions on 7-T FLAIR* increased when the presence of a central vessel was taken into account (from 63 % to 88 %), most obviously for deep white matter lesions (from 69 % to 94 %). High sensitivity remained (81 %). 7-T FLAIR* improves differentiation between MS and vascular lesions based on lesion location, perivascular orientation and presence of hypointense (rims around) lesions. circle A new MRI technique T2*-weighted fluid attenuation inversion recovery (FLAIR*) was investigated. circle FLAIR* at 7-T MRI combines FLAIR and T2* images into a single image. circle FLAIR* at 7 T does not require enhancement with contrast agents. (orig.)

Localized atrophy of the thalamus and slowed cognitive processing speed in MS patients.

Science.gov (United States)

Bergsland, Niels; Zivadinov, Robert; Dwyer, Michael G; Weinstock-Guttman, Bianca; Benedict, Ralph Hb

2016-09-01

Deep gray matter (DGM) atrophy is common in multiple sclerosis (MS), but no studies have investigated surface-based structure changes over time with respect to healthy controls (HCs). Moreover, the relationship between cognition and the spatio-temporal evolution of DGM atrophy is poorly understood. To explore DGM structural differences between MS and HCs over time in relation to neuropsychological (NP) outcomes. The participants were 44 relapsing-remitting and 20 secondary progressive MS patients and 22 HCs. All were scanned using 3T magnetic resonance imaging (MRI) at baseline and 3-year follow-up. NP examination emphasized consensus standard tests of processing speed and memory. We performed both volumetric and shape analysis of DGM structures and assessed their relationships with cognition. Compared to HCs, MS patients presented with significantly smaller DGM volumes. For the thalamus and caudate, differences in shape were mostly localized along the lateral ventricles. NP outcomes were related to both volume and shape of the DGM structures. Over 3 years, decreased cognitive processing speed was related to localized atrophy on the anterior and superior surface of the left thalamus. These findings highlight the role of atrophy in the anterior nucleus of the thalamus and its relation to cognitive decline in MS. © The Author(s), 2015.

LC-MS (/MS) in clinical toxicology screening methods.

Science.gov (United States)

Viette, Véronique; Hochstrasser, Denis; Fathi, Marc

2012-01-01

Toxicological screening is the analysis of biological samples to detect and identify unknown compounds. The high selectivity and sensitivity of liquid chromatography (LC) coupled to mass spectrometry (MS) or tandem mass spectrometry (MS/MS) technology provide an attractive alternative to the current methods (LC-UV, GC/MS, etc.). For these reasons, an increasing number of applications are being published. This paper is a brief overview of LC-MS(/MS) screening methods developed for clinical toxicology in recent years. Various sample treatments, chromatographic separations and detection by mass spectrometry can be combined to obtain screening methods adapted to the constraints and needs of clinical toxicology laboratories. Currently the techniques are in the hands of specialists, mainly in academic institutions. However, the evolution in technology should allow application of these techniques as a tool in toxicology laboratories, thus allowing a more widespread exploitation of their potential.

Most Powerful Eruption in the Universe Discovered

Science.gov (United States)

2005-01-01

Astronomers have found the most powerful eruption seen in the Universe using NASA's Chandra X-ray Observatory. A supermassive black hole generated this eruption by growing at a remarkable rate. This discovery shows the enormous appetite of large black holes, and the profound impact they have on their surroundings. The huge eruption is seen in a Chandra image of the hot, X-ray emitting gas of a galaxy cluster called MS 0735.6+7421. Two vast cavities extend away from the supermassive black hole in the cluster's central galaxy. The eruption - which has lasted for 100 million years and is still going - has generated the energy equivalent to hundreds of millions of gamma-ray bursts. Animation of Eruption from Supermassive Black Hole Animation of Eruption from Supermassive Black Hole This event was caused by gravitational energy release as enormous amounts of matter fell toward a black hole. Most of the matter was swallowed, but some of it was violently ejected before being captured by the black hole. "I was stunned to find that a mass of about 300 million Suns was swallowed," said Brian McNamara of Ohio University in Athens, lead author of the study that appears in the January 6, 2005 issue of Nature. "This is almost as massive as the supermassive black hole that swallowed it." Astronomers are not sure where such large amounts of matter came from. One theory is that gas from the host galaxy catastrophically cooled and was then swallowed by the black hole. Illustration of MS 0735.6+742 Illustration of MS 0735.6+742 The energy released shows that the black hole in MS 0735 has grown very dramatically during this eruption. Previous studies suggest that other large black holes have grown very little in the recent past, and that only smaller black holes are still growing quickly. "This new result is as surprising as it is exciting", said co-author Paul Nulsen of the Harvard-Smithsonian Center of Astrophysics. "This black hole is feasting when it should be fasting." Radio

Analysis of acrylamide by LC-MS/MS and GC-MS in processed Japanese foods.

Science.gov (United States)

Ono, H; Chuda, Y; Ohnishi-Kameyama, M; Yada, H; Ishizaka, M; Kobayashi, H; Yoshida, M

2003-03-01

Acrylamide concentrations in processed foods (63 samples covering 31 product types) from Japan were analysed by LC-MS/MS and GC-MS methods. The limit of detection and limit of quantification of acrylamide were 0.2 ng x ml(-1) (6 fmol) and 0.8 ng x ml(-1) (22 fmol), respectively, by LC-MS/MS, and those of 2,3-dibromopropionamide derived from acrylamide were 12 ng x ml(-1) (52 fmol) and 40 ng x ml(-1) (170 fmol), respectively, by GC-MS. Repeatability given as RSD was 1000 microg x kg(-1). The concentrations in non-whole potato-based snacks, rice crackers processed by grilling or frying, and candied sweet potatoes were lower compared with those in the potato crisps and the whole potato-based fried snacks. One of the whole potato-based fried snacks, however, showed low acrylamide concentration (instant precooked noodles and won-tons were <100 microg x kg(-1) with only one exception. Roasted barley grains for 'Mugi-cha' tea contained 200-600 microg x kg(-1) acrylamide.

Urinary amino acid analysis: a comparison of iTRAQ-LC-MS/MS, GC-MS, and amino acid analyzer.

Science.gov (United States)

Kaspar, Hannelore; Dettmer, Katja; Chan, Queenie; Daniels, Scott; Nimkar, Subodh; Daviglus, Martha L; Stamler, Jeremiah; Elliott, Paul; Oefner, Peter J

2009-07-01

Urinary amino acid analysis is typically done by cation-exchange chromatography followed by post-column derivatization with ninhydrin and UV detection. This method lacks throughput and specificity. Two recently introduced stable isotope ratio mass spectrometric methods promise to overcome those shortcomings. Using two blinded sets of urine replicates and a certified amino acid standard, we compared the precision and accuracy of gas chromatography/mass spectrometry (GC-MS) and liquid chromatography-tandem mass spectrometry (LC-MS/MS) of propyl chloroformate and iTRAQ derivatized amino acids, respectively, to conventional amino acid analysis. The GC-MS method builds on the direct derivatization of amino acids in diluted urine with propyl chloroformate, GC separation and mass spectrometric quantification of derivatives using stable isotope labeled standards. The LC-MS/MS method requires prior urinary protein precipitation followed by labeling of urinary and standard amino acids with iTRAQ tags containing different cleavable reporter ions distinguishable by MS/MS fragmentation. Means and standard deviations of percent technical error (%TE) computed for 20 amino acids determined by amino acid analyzer, GC-MS, and iTRAQ-LC-MS/MS analyses of 33 duplicate and triplicate urine specimens were 7.27+/-5.22, 21.18+/-10.94, and 18.34+/-14.67, respectively. Corresponding values for 13 amino acids determined in a second batch of 144 urine specimens measured in duplicate or triplicate were 8.39+/-5.35, 6.23+/-3.84, and 35.37+/-29.42. Both GC-MS and iTRAQ-LC-MS/MS are suited for high-throughput amino acid analysis, with the former offering at present higher reproducibility and completely automated sample pretreatment, while the latter covers more amino acids and related amines.

CHANDRA OBSERVATION OF POLARIS: CENSUS OF LOW-MASS COMPANIONS

International Nuclear Information System (INIS)

Remage Evans, Nancy; Wolk, Scott J.; Karovska, Margarita; Spitzbart, Bradley; Guinan, Edward; Engle, Scott; Schlegel, Eric; Mason, Brian D.

2010-01-01

We have observed Cepheid Polaris (α UMi A: F7 Ib [Aa] + F6 V [Ab]) with Chandra ACIS-I for 10 ks. An X-ray source was found at the location of Polaris with log L X = 28.89 erg s -1 (0.3-8 keV) and kT = 0.6 keV. A spectrum this soft could come from either the supergiant or the dwarf, as shown by comparable coronal stars. Two resolved low-mass visual companions, 'C' and 'D', are not physical members of the system based on the lack of X-rays (indicating an age older than the Cepheid) and inconsistent proper motions. Polaris B is not an X-ray source, consistent with its early F spectral type, and probably does not have a lower mass companion itself. A possible more distant member is identified, and an additional less plausible one. This provides a complete census of companions out to 0.1 pc covering a mass ratio range of an order of magnitude and a ΔV of nearly 15 mag.

Urinary Amino Acid Analysis: A Comparison of iTRAQ®-LC-MS/MS, GC-MS, and Amino Acid Analyzer

Science.gov (United States)

Kaspar, Hannelore; Dettmer, Katja; Chan, Queenie; Daniels, Scott; Nimkar, Subodh; Daviglus, Martha L.; Stamler, Jeremiah; Elliott, Paul; Oefner, Peter J.

2009-01-01

Urinary amino acid analysis is typically done by cation-exchange chromatography followed by post-column derivatization with ninhydrin and UV detection. This method lacks throughput and specificity. Two recently introduced stable isotope ratio mass spectrometric methods promise to overcome those shortcomings. Using two blinded sets of urine replicates and a certified amino acid standard, we compared the precision and accuracy of gas chromatography/mass spectrometry (GC-MS) and liquid chromatography-tandem mass spectrometry (LC-MS/MS) of propyl chloroformate and iTRAQ® derivatized amino acids, respectively, to conventional amino acid analysis. The GC-MS method builds on the direct derivatization of amino acids in diluted urine with propyl chloroformate, GC separation and mass spectrometric quantification of derivatives using stable isotope labeled standards. The LC-MS/MS method requires prior urinary protein precipitation followed by labeling of urinary and standard amino acids with iTRAQ® tags containing different cleavable reporter ions distinguishable by MS/MS fragmentation. Means and standard deviations of percent technical error (%TE) computed for 20 amino acids determined by amino acid analyzer, GC-MS, and iTRAQ®-LC-MS/MS analyses of 33 duplicate and triplicate urine specimens were 7.27±5.22, 21.18±10.94, and 18.34±14.67, respectively. Corresponding values for 13 amino acids determined in a second batch of 144 urine specimens measured in duplicate or triplicate were 8.39±5.35, 6.23±3.84, and 35.37±29.42. Both GC-MS and iTRAQ®-LC-MS/MS are suited for high-throughput amino acid analysis, with the former offering at present higher reproducibility and completely automated sample pretreatment, while the latter covers more amino acids and related amines. PMID:19481989

XMM-Newton 13H deep field - I. X-ray sources

Science.gov (United States)

Loaring, N. S.; Dwelly, T.; Page, M. J.; Mason, K.; McHardy, I.; Gunn, K.; Moss, D.; Seymour, N.; Newsam, A. M.; Takata, T.; Sekguchi, K.; Sasseen, T.; Cordova, F.

2005-10-01

We present the results of a deep X-ray survey conducted with XMM-Newton, centred on the UK ROSAT13H deep field area. This region covers 0.18 deg2, and is the first of the two areas covered with XMM-Newton as part of an extensive multiwavelength survey designed to study the nature and evolution of the faint X-ray source population. We have produced detailed Monte Carlo simulations to obtain a quantitative characterization of the source detection procedure and to assess the reliability of the resultant sourcelist. We use the simulations to establish a likelihood threshold, above which we expect less than seven (3 per cent) of our sources to be spurious. We present the final catalogue of 225 sources. Within the central 9 arcmin, 68 per cent of source positions are accurate to 2 arcsec, making optical follow-up relatively straightforward. We construct the N(>S) relation in four energy bands: 0.2-0.5, 0.5-2, 2-5 and 5-10 keV. In all but our highest energy band we find that the source counts can be represented by a double power law with a bright-end slope consistent with the Euclidean case and a break around 10-14yergcm-2s-1. Below this flux, the counts exhibit a flattening. Our source counts reach densities of 700, 1300, 900 and 300 deg-2 at fluxes of 4.1 × 10-16,4.5 × 10-16,1.1 × 10-15 and 5.3 × 10-15ergcm-2s-1 in the 0.2-0.5, 0.5-2, 2-5 and 5-10 keV energy bands, respectively. We have compared our source counts with those in the two Chandra deep fields and Lockman hole, and found our source counts to be amongst the highest of these fields in all energy bands. We resolve >51 per cent (>50 per cent) of the X-ray background emission in the 1-2 keV (2-5 keV) energy bands.

Chandra Observations of M31 and their Implications for its ISM

Science.gov (United States)

Primini, F.; Garcia, M.; Murray, S.; Forman, W.; Jones, C.; McClintock, J.

2000-01-01

As part of the Chandra X-ray Observatory's Survey/Monitoring Program of M31, we have been regularly observing the bulge amd inner disk of M31 for nearly 1 year, using both the HRC and ACIS Instruments. We present results from our program th it are of interest to the study of the ISM in M31. In particular, spectral analysis of bright, unresolved x-ray sources in the bulge reveals the presence of significant local x-ray extinction (N(sub H) is about 2 x 10(exp 21)/square cm), and we will attempt to map out this extinction, Further, we find that diffuse emission accounts for a significant fraction of the overall x-ray flux from the bulge. Finally, our search for x-ray counterparts to supernova remnants in M31 yields surprisingly few candidates.

Impacts of Chandra X-ray Observatory Public Communications and Engagement

Science.gov (United States)

Arcand, Kimberly K.; Watzke, Megan; Lestition, Kathleen; Edmonds, Peter

2015-01-01

The Chandra X-ray Observatory Center runs a multifaceted Public Communications & Engagement program encompassing press relations, public engagement, and education. Our goals include reaching a large and diverse audience of national and international scope, establishing direct connections and working relationships with the scientists whose research forms the basis for all products, creating peer-reviewed materials and activities that evolve from an integrated pipeline design and encourage users toward deeper engagement, and developing materials that target underserved audiences such as women, Spanish speakers, and the sight and hearing impaired. This talk will highlight some of the key features of our program, from the high quality curated digital presence to the cycle of research and evaluation that informs our practice at all points of the program creation. We will also discuss the main impacts of the program, from the tens of millions of participants reached through the establishment and sustainability of a network of science 'volunpeers.'

Selenium speciation analysis of Misgurnus anguillicaudatus selenoprotein by HPLC-ICP-MS and HPLC-ESI-MS/MS

Science.gov (United States)

Analytical methods for selenium (Se) speciation were developed using high performance liquid chromatography (HPLC) coupled to either inductively coupled plasma mass spectrometry (ICP-MS) or electrospray ionization tandem mass spectrometry (ESI-MS/MS). Separations of selenomethionine (Se-Met) and sel...

MassSieve: Panning MS/MS peptide data for proteins

OpenAIRE

Slotta, Douglas J.; McFarland, Melinda A.; Markey, Sanford P.

2010-01-01

We present MassSieve, a Java-based platform for visualization and parsimony analysis of single and comparative LC-MS/MS database search engine results. The success of mass spectrometric peptide sequence assignment algorithms has led to the need for a tool to merge and evaluate the increasing data set sizes that result from LC-MS/MS-based shotgun proteomic experiments. MassSieve supports reports from multiple search engines with differing search characteristics, which can increase peptide sequ...

Chandra Observations of Pluto's Escaping Atmosphere in Support of the New Horizons Mission

Science.gov (United States)

McNutt, Ralph, Jr.

2013-09-01

Current models of Pluto's extended N2+CH4 atmosphere are still very uncertain, causing numerous difficulties in optimizing the New Horizons fast flyby operations plan for the dwarf planet. Applying knowledge gained from studying cometary X-ray emission, Chandra ACIS-S photometric imaging of X-rays produced by CXE between the solar wind and Pluto's atmosphere will address both the run of atmospheric density and the interaction of the solar wind with the extended Plutonian atmosphere. Determining the atmosphere's extent and amount of free molecular escape will aid the atmospheric sounding measurements of the NH ALICE instrument, while determining the x-ray luminosity will help the NH PEPSI instrument characterize the solar wind particle environment.

Chandra monitoring of the Galactic Centre magnetar SGR J1745-2900 during the initial 3.5 years of outburst decay

NARCIS (Netherlands)

Coti Zelati, F.; Rea, N.; Turolla, R.; Pons, J.A.; Papitto, A.; Esposito, P.; Israel, G.L.; Campana, S.; Zane, S.; Tiengo, A.; Mignani, R.P.; Mereghetti, S.; Baganoff, F.K.; Haggard, D.; Ponti, G.; Torres, D.F.; Borghese, A.; Elfritz, J.

2017-01-01

We report on 3.5 yr of Chandra monitoring of the Galactic Centre magnetar SGR J1745−2900 since its outburst onset in 2013 April. The magnetar spin-down has shown at least two episodes of period derivative increases so far, and it has slowed down regularly in the past year or so. We observed a

Dynamics of scene representations in the human brain revealed by magnetoencephalography and deep neural networks

Science.gov (United States)

Cichy, Radoslaw Martin; Khosla, Aditya; Pantazis, Dimitrios; Oliva, Aude

2017-01-01

Human scene recognition is a rapid multistep process evolving over time from single scene image to spatial layout processing. We used multivariate pattern analyses on magnetoencephalography (MEG) data to unravel the time course of this cortical process. Following an early signal for lower-level visual analysis of single scenes at ~100 ms, we found a marker of real-world scene size, i.e. spatial layout processing, at ~250 ms indexing neural representations robust to changes in unrelated scene properties and viewing conditions. For a quantitative model of how scene size representations may arise in the brain, we compared MEG data to a deep neural network model trained on scene classification. Representations of scene size emerged intrinsically in the model, and resolved emerging neural scene size representation. Together our data provide a first description of an electrophysiological signal for layout processing in humans, and suggest that deep neural networks are a promising framework to investigate how spatial layout representations emerge in the human brain. PMID:27039703

Biodiversity and Indigenous Uses of Medicinal Plant in the Chandra Prabha Wildlife Sanctuary, Chandauli District, Uttar Pradesh

OpenAIRE

Maurya Santosh Kumar; Seth Ankit; Dev Nath Singh Gautam; Singh Anil Kumar

2015-01-01

Conventional medicines are very important part of Indian culture. In this study the outcome of two-year study of ethnomedicinal uses of plants in Chandra Prabha Wildlife Sanctuary (CPWLS) and nearby area is reported. Information related to different plants which are used by local community in the treatment of many common diseases and well-being in the area was collected. Data on the use of medicinal plants were collected using structured interview of about 122 participants and thorough observ...

Relapsing-Remitting MS (RRMS)

Medline Plus

Full Text Available ... Area Donate Donate Search v What Is MS? Definition of MS What Causes MS? Who Gets MS? ... Support Personal Stories d What Is MS? d Definition of MS Myelin Immune-Mediated Disease T Cells ...

Metabolic profiling of roots of liquorice (Glycyrrhiza glabra) from different geographical areas by ESI/MS/MS and determination of major metabolites by LC-ESI/MS and LC-ESI/MS/MS.

Science.gov (United States)

Montoro, Paola; Maldini, Mariateresa; Russo, Mariateresa; Postorino, Santo; Piacente, Sonia; Pizza, Cosimo

2011-02-20

Liquid chromatography electrospray mass spectrometry (LC-ESI/MS) has been applied to the full characterization of saponins and phenolics in hydroalcoholic extracts of roots of liquorice (Glycyrrhiza glabra). Relative quantitative analyses of the samples with respect to the phenolic constituents and to a group of saponins related to glycyrrhizic acid were performed using LC-ESI/MS. For the saponin constituents, full scan LC-MS/MS fragmentation of the protonated (positive ion mode) or deprotonated (negative ion mode) molecular species generated diagnostic fragment ions that provided information concerning the triterpene skeleton and the number and nature of the substituents. On the basis of the specific fragmentation of glycyrrhizic acid, an LC-MS/MS method was developed in order to quantify the analyte in the liquorice root samples. Chinese G. glabra roots contained the highest levels of glycyrrhizic acid, followed by those from Italy (Calabria). Copyright © 2010 Elsevier B.V. All rights reserved.

Benefits of Deep Transcranial Magnetic Stimulation in Alzheimer Disease: Case Series.

Science.gov (United States)

Avirame, Keren; Stehberg, Jimmy; Todder, Doron

2016-06-01

Patients diagnosed with Alzheimer disease (AD) show severe cognitive deficits. Decline in memory, language, and executive function have repeatedly been reported. Although AD affects 60% to 80% of demented elderly patients, there is currently no cure and limited treatment alternatives. The aim of the study was to evaluate the feasibility of stimulating prefrontal cortex (PFC) with deep transcranial magnetic stimulation (dTMS) to ameliorate cognitive deficits in patients suffering from AD. Eleven patients (6 males; mean [SD] age, 76 [7] years) in moderate to severe stages of AD received dTMS over the PFC for 20 sessions. Computerized battery (Mindstreams [MS]) and neuropsychological testing (Addenbrooke Cognitive Examination [ACE]) were used to assess cognitive performance before and after treatment. Compared with baseline, 60% of patients performed better on the MS battery and 77% of patients performed better on the ACE testing at the end of dTMS treatment. None of the patients performed worse on both tests at the end of treatment. The DTMS effects on the group mean in ACE and MS approached significance (P = 0.065 and P = 0.086, respectively). A dTMS-induced improvement in the ACE was significant (P = 0.001) on patients in more progressed stage (n = 6). Change in ACE negatively correlated with score at baseline. In sum, the current report of this novel technique indicates that deep stimulation might lead to preservation and even improvement of cognitive functions, at least during the time of treatment. Further examinations should report of long-term effects of this technique.

Paired-Pulse TMS and Fine-Wire Recordings Reveal Short-Interval Intracortical Inhibition and Facilitation of Deep Multifidus Muscle Fascicles.

Directory of Open Access Journals (Sweden)

Hugo Massé-Alarie

Full Text Available Paired-pulse transcranial magnetic stimulation (ppTMS is used to probe inhibitory and excitatory networks within the primary motor cortex (M1. These mechanisms are identified for limb muscles but it is unclear whether they share properties with trunk muscles. The aim was to determine whether it was possible to test the intracortical inhibition and facilitation of the deep multifidus muscle fascicles (DM and at which inter-stimulus intervals (ISI.In ten pain-free individuals, TMS was applied over M1 and motor evoked potentials (MEP were recorded using fine-wire electrodes in DM. MEPs were conditioned with subthreshold stimuli at ISIs of 1 to 12 ms to test short-interval intracortical inhibition (SICI and at 15 ms for long-interval intracortical facilitation. Short-interval facilitation (SICF was tested using 1-ms ISI.SICI of DM was consistently obtained with ISI of 1-, 3-, 4- and 12-ms. Facilitation of DM MEP was only identified using SICF paradigm.A similar pattern of MEP modulation with ISI changes for deep trunk and limb muscles implies that M1 networks share some functional properties.The ppTMS paradigm presents a potential to determine how M1 inhibitory and excitatory mechanisms participate in brain re-organization in back pain that affects control of trunk muscles.

Comparative Analysis and Variability of the Jovian X-Ray Spectra Detected by the Chandra and XMM-Newton Observatories

Energy Technology Data Exchange (ETDEWEB)

Hui, Yawei [ORNL; Schultz, David Robert [ORNL; Kharchenko, Vasili A [ORNL; Bhardwaj, Anil [Vikram Sarabhai Space Center, Trivandrum, India; Branduardi-Raymont, Graziella [University College, London; Stancil, Phillip C. [University of Georgia, Athens, GA; Cravens, Thomas E. E. [University of Kansas; Lisse, Carey M. [Johns Hopkins University; Dalgarno, A. [Harvard-Smithsonian Center for Astrophysics

2010-01-01

Expanding upon recent work, a more comprehensive spectral model based on charge exchange induced X-ray emission by ions precipitating into the Jovian atmosphere is used to provide new understanding of the polar auroras. In conjunction with the Xspec spectral fitting software, the model is applied to analyze observations from both Chandra and XMM-Newton by systematically varying the initial precipitating ion parameters to obtain the best fit model for the observed spectra. In addition to the oxygen and sulfur ions considered previously, carbon is included to discriminate between solar wind and Jovian magnetospheric ion origins, enabled by the use of extensive databases of both atomic collision cross sections and radiative transitions. On the basis of fits to all the Chandra observations, we find that carbon contributes negligibly to the observed polar X-ray emission suggesting that the highly accelerated precipitating ions are of magnetospheric origin. Most of the XMM-Newton fits also favor this conclusion with one exception that implies a possible carbon contribution. Comparison among all the spectra from these two observatories in light of the inferred initial energies and relative abundances of precipitating ions from the modeling show that they are significantly variable in time (observation date) and space (north and south polar X-ray auroras).

DeepPy: Pythonic deep learning

DEFF Research Database (Denmark)

Larsen, Anders Boesen Lindbo

This technical report introduces DeepPy – a deep learning framework built on top of NumPy with GPU acceleration. DeepPy bridges the gap between highperformance neural networks and the ease of development from Python/NumPy. Users with a background in scientific computing in Python will quickly...... be able to understand and change the DeepPy codebase as it is mainly implemented using high-level NumPy primitives. Moreover, DeepPy supports complex network architectures by letting the user compose mathematical expressions as directed graphs. The latest version is available at http...

The Chandra Source Catalog: Source Variability

Science.gov (United States)

Nowak, Michael; Rots, A. H.; McCollough, M. L.; Primini, F. A.; Glotfelty, K. J.; Bonaventura, N. R.; Chen, J. C.; Davis, J. E.; Doe, S. M.; Evans, J. D.; Evans, I.; Fabbiano, G.; Galle, E. C.; Gibbs, D. G., II; Grier, J. D.; Hain, R.; Hall, D. M.; Harbo, P. N.; He, X.; Houck, J. C.; Karovska, M.; Lauer, J.; McDowell, J. C.; Miller, J. B.; Mitschang, A. W.; Morgan, D. L.; Nichols, J. S.; Plummer, D. A.; Refsdal, B. L.; Siemiginowska, A. L.; Sundheim, B. A.; Tibbetts, M. S.; van Stone, D. W.; Winkelman, S. L.; Zografou, P.

2009-09-01

The Chandra Source Catalog (CSC) contains fields of view that have been studied with individual, uninterrupted observations that span integration times ranging from 1 ksec to 160 ksec, and a large number of which have received (multiple) repeat observations days to years later. The CSC thus offers an unprecedented look at the variability of the X-ray sky over a broad range of time scales, and across a wide diversity of variable X-ray sources: stars in the local galactic neighborhood, galactic and extragalactic X-ray binaries, Active Galactic Nuclei, etc. Here we describe the methods used to identify and quantify source variability within a single observation, and the methods used to assess the variability of a source when detected in multiple, individual observations. Three tests are used to detect source variability within a single observation: the Kolmogorov-Smirnov test and its variant, the Kuiper test, and a Bayesian approach originally suggested by Gregory and Loredo. The latter test not only provides an indicator of variability, but is also used to create a best estimate of the variable lightcurve shape. We assess the performance of these tests via simulation of statistically stationary, variable processes with arbitrary input power spectral densities (here we concentrate on results of red noise simulations) at variety of mean count rates and fractional root mean square variabilities relevant to CSC sources. We also assess the false positive rate via simulations of constant sources whose sole source of fluctuation is Poisson noise. We compare these simulations to an assessment of the variability found in real CSC sources, and estimate the variability sensitivities of the CSC.

Analysis of poly-beta-hydroxybutyrate in environmental samples by GC-MS/MS.

Science.gov (United States)

Elhottová, D; Tríska, J; Petersen, S O; Santrůcková, H

2000-05-01

Application of gas chromatography-mass spectrometry (GC-MS) can significantly improve trace analyses of compounds in complex matrices from natural environments compared to gas chromatography only. A GC-MS/MS technique for determination of poly-beta-hydroxybutyrate (PHB), a bacterial storage compound, has been developed and used for analysis of two soils stored for up to 319 d, fresh samples of sewage sludge, as well as a pure culture of Bacillus megaterium. Specific derivatization of beta-hydroxybutyrate (3-OH C4:0) PHB monomer units by N-tert-butyl-dimethylsilyl-N-methyltrifluoracetamide (MTBSTFA) improved chromatographic and mass spectrometric properties of the analyte. The diagnostic fragmentation scheme of the derivates tert-butyldimethylsilyl ester and ether of beta-hydroxybutyric acid (MTBSTFA-HB) essential for the PHB identification was shown. The ion trap MS was used, therefore the scan gave the best sensitivity and with MS/MS the noise decreased, so the S/N was better and also with second fragmentation the amount of ions increased compared to SIM. The detection limit for MTBSTFA-HB by GC-MS/MS was about 10(-13) g microL(-1) of injected volume, while by GC (FID) and GC-MS (scan) it was around 10(-10) g microL(-1) of injected volume. Sensitivity of GC-MS/MS measurements of PHB in arable soil and activated sludge samples was down to 10 pg of PHB g(-1) dry matter. Comparison of MTBSTFA-HB detection in natural soil sample by GC (FID), GC-MS (scan) and by GC-MS/MS demonstrated potentials and limitations of the individual measurement techniques.

The Chandra Source Catalog : Google Earth Interface

Science.gov (United States)

Glotfelty, Kenny; McLaughlin, W.; Evans, I.; Evans, J.; Anderson, C. S.; Bonaventura, N. R.; Davis, J. E.; Doe, S. M.; Fabbiano, G.; Galle, E. C.; Gibbs, D. G., II; Grier, J. D.; Hain, R.; Hall, D. M.; Harbo, P. N.; He, H.; Houck, J. C.; Karovska, M.; Kashyap, V. L.; Lauer, J.; McCollough, M. L.; McDowell, J. C.; Miller, J. B.; Mitschang, A. W.; Morgan, D. L.; Mossman, A. E.; Nichols, J. S.; Nowak, M. A.; Plummer, D. A.; Primini, F. A.; Refsdal, B. L.; Rots, A. R.; Siemiginowska, A. L.; Sundheim, B. A.; Tibbetts, M. S.; van Stone, D. W.; Winkelman, S. L.; Zografou, P.

2009-09-01

The Chandra Source Catalog (CSC) contains multi-resolution, exposure corrected, background subtracted, full-field images that are stored as individual FITS files and as three-color JPEG files. In this poster we discuss how we took these data and were able to, with relatively minimal effort, convert them for use with the Google Earth application in its ``Sky'' mode. We will highlight some of the challenges which include converting the data to the required Mercator projection, reworking the 3-color algorithm for pipeline processing, and ways to reduce the data volume through re-binning, using color-maps, and special Keyhole Markup Language (kml) tags to only load images on-demand. The result is a collection of some 11,000 3-color images that are available for all the individual observation in the CSC Release 1. We also have made available all ˜4000 Field-of-View outlines (with per-chip regions), which turns out are trivial to produce starting with a simple dmlist command. In the first week of release, approximately 40% of the images have been accessed at least once through some 50,000 individual web hits which have served over 4Gb of data to roughly 750 users in 60+ countries. We will also highlight some future directions we are exploring, including real-time catalog access to individual source properties and eventual access to file based products such as FITS images, spectra, and light-curves.

A Search for New Galactic Magnetars in Archival Chandra and XMM-Newton Observations

Science.gov (United States)

Muno, M. P.; Gaensler, B. M.; Nechita, A.; Miller, J. M.; Slane, P. O.

2008-06-01

We present constraints on the number of Galactic magnetars, which we have established by searching for sources with periodic variability in 506 archival Chandra observations and 441 archival XMM-Newton observations of the Galactic plane (| b| fall within our survey, then there are 59+ 92-32 in the Galaxy. Barely detectable magnetars (LX = 3 × 1033 ergs s-1 and Arms = 15% ) could have been identified throughout ≈0.4% of the spiral arms. The lack of new examples implies that birth rate of magnetars is between 0.003 and 0.06 yr-1. Therefore, the birth rate of magnetars is at least 10% of that for normal radio pulsars, and could exceed that value, unless transient magnetars are active for gtrsim105 yr.

Further constraints on the evolution of K-s-selected galaxies in the GOODS/CDFS field

NARCIS (Netherlands)

Caputi, KI; McLure, RJ; Dunlop, JS; Cirasuolo, M; Schael, AM

2006-01-01

We have selected and analysed the properties of a sample of 2905 K-s <21.5 galaxies in similar to 131 arcmin(2) of the Great Observatories Origins Deep Survey (GOODS) Chandra Deep Field South (CDFS), to obtain further constraints on the evolution of K-s-selected galaxies with respect to the results

Ionic drift velocity measurement on hot-pressed Ag ion conducting ...

Indian Academy of Sciences (India)

Shri Shankaracharya Institute of Professional Management & Technology, Raipur 492 015, India. MS received 29 October 2014; accepted 14 August 2015. Abstract. Ionic drift ..... Chandra S 1981 Superionic solids—principle and applications.

Cannabinoids determination in oral fluid by SPME-GC/MS and UHPLC-MS/MS and its application on suspected drivers.

Science.gov (United States)

Anzillotti, Luca; Castrignanò, Erika; Strano Rossi, Sabina; Chiarotti, Marcello

2014-12-01

The confirmation of Δ9-tetrahydrocannabinol (THC) in oral fluid (OF) is an important issue for assessing Driving Under the Influence of Drugs (DUID). The aim of this research was to develop a highly sensitive method with minimal sample pre-treatment suitable for the analysis of small OF volumes (100 μL) for the confirmation of cannabinoids in DUID cases. Two methods were compared for the confirmation of THC in residual OF samples, obtained from a preliminary on-site screening with commercial devices. An ultra high performance LC-MS (UHPLC-MS/MS) method and an SPME-GC/MS method were hence developed. 100 μL of the residual mixture OF/preservative buffer or neat OF was simply added to 10 μL of THC-D3 (1 μg/mL) and submitted to the two different analyses: A - direct injection of 10 μL in UHPLC-MS/MS in positive electrospray ionisation (ESI) mode and B - sampling for 30 min with SPME (100 μm polydimethylsiloxane or PDMS fibre) and direct injection by desorption of the fibre in the GC injection port. The lowest limit of detection (LLOD) of THC was 2 ng/mL in UHPLC-MS/MS and 0.5 ng/mL in SPME-GC/MS. In addition, cannabidiol (CBD) and cannabinol (CBN) could be detected in GC/MS equipment at 2 ng/mL, whilst in UHPLC-MS/MS the LLOD was 20 ng/mL. Both methods were applied to 70 samples coming from roadside tests. By SPME-GC/MS analysis, THC was confirmed in 42 samples, whilst CBD was detected in 21 of them, along with CBN in 14 samples. THC concentrations ranged from traces below the lowest limit of quantification or LLOQ (2 ng/mL) up to 690 ng/mL. Copyright © 2014 Forensic Science Society. Published by Elsevier Ireland Ltd. All rights reserved.

Software ion scan functions in analysis of glycomic and lipidomic MS/MS datasets.

Science.gov (United States)

Haramija, Marko

2018-03-01

Hardware ion scan functions unique to tandem mass spectrometry (MS/MS) mode of data acquisition, such as precursor ion scan (PIS) and neutral loss scan (NLS), are important for selective extraction of key structural data from complex MS/MS spectra. However, their software counterparts, software ion scan (SIS) functions, are still not regularly available. Software ion scan functions can be easily coded for additional functionalities, such as software multiple precursor ion scan, software no ion scan, and software variable ion scan functions. These are often necessary, since they allow more efficient analysis of complex MS/MS datasets, often encountered in glycomics and lipidomics. Software ion scan functions can be easily coded by using modern script languages and can be independent of instrument manufacturer. Here we demonstrate the utility of SIS functions on a medium-size glycomic MS/MS dataset. Knowledge of sample properties, as well as of diagnostic and conditional diagnostic ions crucial for data analysis, was needed. Based on the tables constructed with the output data from the SIS functions performed, a detailed analysis of a complex MS/MS glycomic dataset could be carried out in a quick, accurate, and efficient manner. Glycomic research is progressing slowly, and with respect to the MS experiments, one of the key obstacles for moving forward is the lack of appropriate bioinformatic tools necessary for fast analysis of glycomic MS/MS datasets. Adding novel SIS functionalities to the glycomic MS/MS toolbox has a potential to significantly speed up the glycomic data analysis process. Similar tools are useful for analysis of lipidomic MS/MS datasets as well, as will be discussed briefly. Copyright © 2017 John Wiley & Sons, Ltd.

VizieR Online Data Catalog: Multiwavelength photometry of CDFS X-ray sources (Brusa+, 2009)

Science.gov (United States)

Brusa, M.; Fiore, F.; Santini, P.; Grazian, A.; Comastri, A.; Zamorani, G.; Hasinger, G.; Merloni, A.; Civano, F.; Fontana, A.; Mainieri, V.

2010-03-01

The co-evolution of host galaxies and the active black holes which reside in their centre is one of the most important topics in modern observational cosmology. Here we present a study of the properties of obscured active galactic nuclei (AGN) detected in the CDFS 1 Ms observation and their host galaxies. We limited the analysis to the MUSIC area, for which deep K-band observations obtained with ISAAC@VLT are available, ensuring accurate identifications of the counterparts of the X-ray sources as well as reliable determination of photometric redshifts and galaxy parameters, such as stellar masses and star formation rates. In particular, we: 1) refined the X-ray/infrared/optical association of 179 sources in the MUSIC area detected in the Chandra observation; 2) studied the host galaxies observed and rest frame colors and properties. (2 data files).

Neutron Stars and Black Holes New clues from Chandra and XMM-Newton

CERN Multimedia

CERN. Geneva. Audiovisual Unit

2002-01-01

Neutron stars and black holes, the most compact astrophysical objects, have become observable in many different ways during the last few decades. We will first review the phenomenology and properties of neutron stars and black holes (stellar and supermassive) as derived from multiwavelength observatories. Recently much progress has been made by means of the new powerful X-ray observatories Chandra and XMM-Newton which provide a substantial increase in sensitivity as well as spectral and angular resolution compared with previous satellites like ROSAT and ASCA. We shall discuss in more detail two recent topics: (1) The attempts to use X-ray spectroscopy for measuring the radii of neutron stars which depend on the equation of state at supranuclear densities. Have quark stars been detected? (2) The diagnostics of the strong gravity regions around supermassive black holes using X-ray spectroscopy.

A Chandra High-Resolution X-ray Image of Centaurus A.

Science.gov (United States)

Kraft; Forman; Jones; Kenter; Murray; Aldcroft; Elvis; Evans; Fabbiano; Isobe; Jerius; Karovska; Kim; Prestwich; Primini; Schwartz; Schreier; Vikhlinin

2000-03-01

We present first results from a Chandra X-Ray Observatory observation of the radio galaxy Centaurus A with the High-Resolution Camera. All previously reported major sources of X-ray emission including the bright nucleus, the jet, individual point sources, and diffuse emission are resolved or detected. The spatial resolution of this observation is better than 1&arcsec; in the center of the field of view and allows us to resolve X-ray features of this galaxy not previously seen. In particular, we resolve individual knots of emission in the inner jet and diffuse emission between the knots. All of the knots are diffuse at the 1&arcsec; level, and several exhibit complex spatial structure. We find the nucleus to be extended by a few tenths of an arcsecond. Our image also suggests the presence of an X-ray counterjet. Weak X-ray emission from the southwest radio lobe is also seen, and we detect 63 pointlike galactic sources (probably X-ray binaries and supernova remnants) above a luminosity limit of approximately 1.7x1037 ergs s-1.

Analytical Method Details (MS): SE52_MS01 [Metabolonote[Archive

Lifescience Database Archive (English)

Full Text Available stem and Waters Q-Tof Premier UPLC-QTOF-MS ESI Negative The eluates (3 μl) were subsequently subjected to metabolome...DS column (LC-ESI-Q-Tof/MS, HPLC: Waters Acquity UPLC system; MS: Waters Q-Tof Premier). The metabolome...d (Matsuda et al., 2009c, 2010a). Briefly, the metabolome data were obtained in the negative ion mode (m/z 1... the complex nature of the metabolome data. To construct MS2T libraries, the extracts of five ecotypes were

Information-dependent acquisition-mediated LC-MS/MS screening procedure with semiquantitative potential.

Science.gov (United States)

Decaestecker, Tineke N; Vande Casteele, Sofie R; Wallemacq, Pierre E; Van Peteghem, Carlos H; Defore, Dieter L; Van Bocxlaer, Jan F

2004-11-01

The development of a LC-MS/MS general unknown screening procedure for toxicologically relevant substances in blood samples by means of information-dependent acquisition on a Q-TOF is reported. IDA is an artificial intelligence-based product ion scan mode providing automatic "on-the-fly" MS to MS/MS switching. By performing information-dependent scanning at two different fragmentation energies, two collision-induced dissociation product ion spectra for each of the detected compounds are generated. As such, information-rich MS/MS spectra are obtained from precursor ions not known beforehand. In addition, limitation of the MS/MS acquisition time to an acceptable minimum resulted in an almost instantaneous switch back to the MS mode. As such, this approach provided MS chromatograms that still could be of use for semiquantitative purposes. Since the switching intensity threshold, unequivocally related to the background noise, proved a critical parameter, the solid-phase extraction procedure, the liquid chromatographic conditions, and the mass spectrometric parameters all were optimized to the advantage of information-dependent acquisition. Finally, the screening procedure we developed was benchmarked, on one hand, qualitatively against the results obtained from traditional GUS approaches in a number of routine toxicological laboratories (20 samples) and, on the other hand, quantitatively with respect to its potential against established LC-MS/MS methods (7 samples). The procedure performed very well from a qualitative point of view; almost all of the drugs detected by the conventional techniques were identified, as well as additional drugs that were not previously reported. The procedure proved well-suited for an initial semiquantitative assessment, as is customary in, for example, forensic toxicology before accurate intoxication levels are determined using targeted analytical analyses.

Chandra Observations of Galaxy Zoo Mergers: Frequency of Binary Active Nuclei in Massive Mergers

Science.gov (United States)

Teng, Stacy H.; Schawinski, Kevin; Urry, C. Megan; Darg, Dan W.; Kaviraj, Sugata; Oh, Kyuseok; Bonning, Erin W.; Cardamone, Carolin N.; Keel, William C.; Lintott, Chris J.;

CANDELS/GOODS-S, CDFS, and ECDFS: photometric redshifts for normal and X-ray-detected galaxies

Energy Technology Data Exchange (ETDEWEB)

Hsu, Li-Ting; Salvato, Mara; Nandra, Kirpal; Brusa, Marcella; Bender, Ralf; Buchner, Johannes; Brightman, Murray; Georgakakis, Antonis [Max-Planck-Institut für extraterrestrische Physik, Giessenbachstrasse, D-85748 Garching (Germany); Donley, Jennifer L. [Los Alamos National Laboratory, Los Alamos, NM (United States); Kocevski, Dale D. [Department of Physics and Astronomy, University of Kentucky, Lexington, KY 40506 (United States); Guo, Yicheng; Barro, Guillermo; Faber, Sandra M. [UCO/Lick Observatory, Department of Astronomy and Astrophysics, University of California, Santa Cruz, CA (United States); Hathi, Nimish P. [Aix Marseille Université, CNRS, LAM (Laboratoire d' Astrophysique de Marseille) UMR 7326, F-13388 Marseille (France); Rangel, Cyprian [Astrophysics Group, Imperial College London, Blackett Laboratory, Prince Consort Road, London SW7 2AZ (United Kingdom); Willner, S. P.; Ashby, Matthew L. N. [Harvard-Smithsonian Center for Astrophysics, Cambridge, MA (United States); Budavári, Tamás; Szalay, Alexander S. [Department of Physics and Astronomy, The Johns Hopkins University, Baltimore, MD (United States); Dahlen, Tomas [Space Telescope Science Institute, Baltimore, MD (United States); and others

2014-11-20

We present photometric redshifts and associated probability distributions for all detected sources in the Extended Chandra Deep Field South (ECDFS). This work makes use of the most up-to-date data from the Cosmic Assembly Near-IR Deep Legacy Survey (CANDELS) and the Taiwan ECDFS Near-Infrared Survey (TENIS) in addition to other data. We also revisit multi-wavelength counterparts for published X-ray sources from the 4 Ms CDFS and 250 ks ECDFS surveys, finding reliable counterparts for 1207 out of 1259 sources (∼96%). Data used for photometric redshifts include intermediate-band photometry deblended using the TFIT method, which is used for the first time in this work. Photometric redshifts for X-ray source counterparts are based on a new library of active galactic nuclei/galaxy hybrid templates appropriate for the faint X-ray population in the CDFS. Photometric redshift accuracy for normal galaxies is 0.010 and for X-ray sources is 0.014 and outlier fractions are 4% and 5.2%, respectively. The results within the CANDELS coverage area are even better, as demonstrated both by spectroscopic comparison and by galaxy-pair statistics. Intermediate-band photometry, even if shallow, is valuable when combined with deep broadband photometry. For best accuracy, templates must include emission lines.

CANDELS/GOODS-S, CDFS, and ECDFS: photometric redshifts for normal and X-ray-detected galaxies

International Nuclear Information System (INIS)

Hsu, Li-Ting; Salvato, Mara; Nandra, Kirpal; Brusa, Marcella; Bender, Ralf; Buchner, Johannes; Brightman, Murray; Georgakakis, Antonis; Donley, Jennifer L.; Kocevski, Dale D.; Guo, Yicheng; Barro, Guillermo; Faber, Sandra M.; Hathi, Nimish P.; Rangel, Cyprian; Willner, S. P.; Ashby, Matthew L. N.; Budavári, Tamás; Szalay, Alexander S.; Dahlen, Tomas

2014-01-01

We present photometric redshifts and associated probability distributions for all detected sources in the Extended Chandra Deep Field South (ECDFS). This work makes use of the most up-to-date data from the Cosmic Assembly Near-IR Deep Legacy Survey (CANDELS) and the Taiwan ECDFS Near-Infrared Survey (TENIS) in addition to other data. We also revisit multi-wavelength counterparts for published X-ray sources from the 4 Ms CDFS and 250 ks ECDFS surveys, finding reliable counterparts for 1207 out of 1259 sources (∼96%). Data used for photometric redshifts include intermediate-band photometry deblended using the TFIT method, which is used for the first time in this work. Photometric redshifts for X-ray source counterparts are based on a new library of active galactic nuclei/galaxy hybrid templates appropriate for the faint X-ray population in the CDFS. Photometric redshift accuracy for normal galaxies is 0.010 and for X-ray sources is 0.014 and outlier fractions are 4% and 5.2%, respectively. The results within the CANDELS coverage area are even better, as demonstrated both by spectroscopic comparison and by galaxy-pair statistics. Intermediate-band photometry, even if shallow, is valuable when combined with deep broadband photometry. For best accuracy, templates must include emission lines.

Automated protein identification by the combination of MALDI MS and MS/MS spectra from different instruments.

Science.gov (United States)

Levander, Fredrik; James, Peter

2005-01-01

The identification of proteins separated on two-dimensional gels is most commonly performed by trypsin digestion and subsequent matrix-assisted laser desorption ionization (MALDI) with time-of-flight (TOF). Recently, atmospheric pressure (AP) MALDI coupled to an ion trap (IT) has emerged as a convenient method to obtain tandem mass spectra (MS/MS) from samples on MALDI target plates. In the present work, we investigated the feasibility of using the two methodologies in line as a standard method for protein identification. In this setup, the high mass accuracy MALDI-TOF spectra are used to calibrate the peptide precursor masses in the lower mass accuracy AP-MALDI-IT MS/MS spectra. Several software tools were developed to automate the analysis process. Two sets of MALDI samples, consisting of 142 and 421 gel spots, respectively, were analyzed in a highly automated manner. In the first set, the protein identification rate increased from 61% for MALDI-TOF only to 85% for MALDI-TOF combined with AP-MALDI-IT. In the second data set the increase in protein identification rate was from 44% to 58%. AP-MALDI-IT MS/MS spectra were in general less effective than the MALDI-TOF spectra for protein identification, but the combination of the two methods clearly enhanced the confidence in protein identification.

Contributions of the "Great" X-Ray Observatories (XMM-Newton and Chandra) to Astronomy and Astrophysics

Science.gov (United States)

Weisskopf, Martin

2011-01-01

NASA s Chandra X-ray Observatory and ESA s XMM-Newton made their first observations over a decade ago. The unprecedented and complementary capabilities of these observatories to detect, image, and measure the energy of cosmic X-rays, achieved less than 50 years after the first detection of an extra-solar X-ray source, represent an increase in sensitivity comparable in going from naked-eye observations to the most powerful optical telescopes over the past 400 years. In this presentation we highlight some of the many discoveries made using these powerful X-ray observatories that have transformed 21st century astronomy. We briefly discuss future prospects for this truly exciting field.

Application of Tandem Two-Dimensional Mass Spectrometry for Top-Down Deep Sequencing of Calmodulin.

Science.gov (United States)

Floris, Federico; Chiron, Lionel; Lynch, Alice M; Barrow, Mark P; Delsuc, Marc-André; O'Connor, Peter B

2018-06-04

Two-dimensional mass spectrometry (2DMS) involves simultaneous acquisition of the fragmentation patterns of all the analytes in a mixture by correlating their precursor and fragment ions by modulating precursor ions systematically through a fragmentation zone. Tandem two-dimensional mass spectrometry (MS/2DMS) unites the ultra-high accuracy of Fourier transform ion cyclotron resonance (FT-ICR) MS/MS and the simultaneous data-independent fragmentation of 2DMS to achieve extensive inter-residue fragmentation of entire proteins. 2DMS was recently developed for top-down proteomics (TDP), and applied to the analysis of calmodulin (CaM), reporting a cleavage coverage of about ~23% using infrared multiphoton dissociation (IRMPD) as fragmentation technique. The goal of this work is to expand the utility of top-down protein analysis using MS/2DMS in order to extend the cleavage coverage in top-down proteomics further into the interior regions of the protein. In this case, using MS/2DMS, the cleavage coverage of CaM increased from ~23% to ~42%. Graphical Abstract Two-dimensional mass spectrometry, when applied to primary fragment ions from the source, allows deep-sequencing of the protein calmodulin.

Chandra observations of Jupiter's X-ray Aurora during Juno upstream and apojove intervals

Science.gov (United States)

Dunn, W.; Jackman, C. M.; Kraft, R.; Gladstone, R.; Branduardi-Raymont, G.; Knigge, C.; Altamirano, D.; Elsner, R.; Kammer, J.

2017-12-01

The Chandra space telescope has recently conducted a number of campaigns to observe Jupiter's X-ray aurora. The first set of campaigns took place in summer 2016 while the Juno spacecraft was upstream of the planet sampling the solar wind. The second set of campaigns took place in February, June and August 2017 at times when the Juno spacecraft was at apojove. These campaigns were planned following the Juno orbit correction to capitalise on the opportunity to image the X-ray emission while Juno was orbiting close to the expected position of the magnetopause. Previous work has suggested that the auroral X-ray emissions map close to the magnetopause boundary [e.g. Vogt et al., 2015; Kimura et al., 2016; Dunn et al., 2016] and thus in situ spacecraft coverage in this region combined with remote observation of the X-rays afford the chance to constrain the drivers of these energetic emissions and determine if they originate on open or closed field lines. We aim to examine possible drivers of X-ray emission including reconnection and the Kelvin-Helmholtz instability and to explore the role of the solar wind in controlling the emissions. We report on these upstream and apojove campaigns including intensities and periodicities of auroral X-ray emissions. This new era of jovian X-ray astronomy means we have more data than ever before, long observing windows (up to 72 ks for this Chandra set), and successive observations relatively closely spaced in time. These features combine to allow us to pursue novel methods for examining periodicities in the X-ray emission. Our work will explore significance testing of emerging periodicities, and the search for coherence in X-ray pulsing over weeks and months, seeking to understand the robustness and regularity of previously reported hot spot X-ray emissions. The periods that emerge from our analysis will be compared against those which emerge from radio and UV wavelengths.

Molecular analysis of intact preen waxes of Calidris Canutus (Aves: Scolopacidae) by GC/MS and GC/MS/MS

NARCIS (Netherlands)

Sinninghe Damsté, J.S.; Dekker, M.H.A.; Piersma, T.

2000-01-01

The intact preen wax esters of the red knot Calidris canutus were studied with gas chromatography/mass spectrometry (GC/MS) and GC/MS/MS. In this latter technique, transitions from the molecular ion to fragment ions representing the fatty acid moiety of the wax esters were measured, providing

Relapsing-Remitting MS (RRMS)

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Relapsing-Remitting MS (RRMS)

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Relapsing-Remitting MS (RRMS)

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Full Text Available ... d Living Well with MS d Diet, Exercise & Healthy Behaviors Diet & Nutrition Exercise Heat & Temperature Sensitivity Sleep Vaccinations Women's Health Unhealthy Habits Managing MS and Another Condition Aging with MS Anesthesia and Surgery Managing Your MS ...

Relapsing-Remitting MS (RRMS)

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Full Text Available ... to navigation Skip to content Menu Navigation National Multiple Sclerosis Society Sign In In Your Area Donate Donate ... of MS What Causes MS? Who Gets MS? Multiple Sclerosis FAQs Types of MS Related Conditions Symptoms & Diagnosis ...

Relapsing-Remitting MS (RRMS)

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Full Text Available ... Relapsing-remitting MS (RRMS) Share this page Facebook Twitter Email Relapsing-remitting MS (RRMS) Relapsing-remitting MS ( ... Start Here Colophon Stay Informed Join Us Facebook Twitter LinkedIn YouTube Pinterest MS Connection About the Society ...

CHANDRA ACIS SURVEY OF X-RAY POINT SOURCES: THE SOURCE CATALOG

Energy Technology Data Exchange (ETDEWEB)

Wang, Song; Liu, Jifeng; Qiu, Yanli; Bai, Yu; Yang, Huiqin; Guo, Jincheng; Zhang, Peng, E-mail: jfliu@bao.ac.cn, E-mail: songw@bao.ac.cn [Key Laboratory of Optical Astronomy, National Astronomical Observatories, Chinese Academy of Sciences, Beijing 100012 (China)

2016-06-01

The Chandra archival data is a valuable resource for various studies on different X-ray astronomy topics. In this paper, we utilize this wealth of information and present a uniformly processed data set, which can be used to address a wide range of scientific questions. The data analysis procedures are applied to 10,029 Advanced CCD Imaging Spectrometer observations, which produces 363,530 source detections belonging to 217,828 distinct X-ray sources. This number is twice the size of the Chandra Source Catalog (Version 1.1). The catalogs in this paper provide abundant estimates of the detected X-ray source properties, including source positions, counts, colors, fluxes, luminosities, variability statistics, etc. Cross-correlation of these objects with galaxies shows that 17,828 sources are located within the D {sub 25} isophotes of 1110 galaxies, and 7504 sources are located between the D {sub 25} and 2 D {sub 25} isophotes of 910 galaxies. Contamination analysis with the log N –log S relation indicates that 51.3% of objects within 2 D {sub 25} isophotes are truly relevant to galaxies, and the “net” source fraction increases to 58.9%, 67.3%, and 69.1% for sources with luminosities above 10{sup 37}, 10{sup 38}, and 10{sup 39} erg s{sup −1}, respectively. Among the possible scientific uses of this catalog, we discuss the possibility of studying intra-observation variability, inter-observation variability, and supersoft sources (SSSs). About 17,092 detected sources above 10 counts are classified as variable in individual observation with the Kolmogorov–Smirnov (K–S) criterion ( P {sub K–S} < 0.01). There are 99,647 sources observed more than once and 11,843 sources observed 10 times or more, offering us a wealth of data with which to explore the long-term variability. There are 1638 individual objects (∼2350 detections) classified as SSSs. As a quite interesting subclass, detailed studies on X-ray spectra and optical spectroscopic follow-up are needed to

Relapsing-Remitting MS (RRMS)

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Relapsing-Remitting MS (RRMS)

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X-ray/ultraviolet observing campaign of the Markarian 279 active galactic nucleus outflow: a close look at the absorbing/emitting gas with Chandra-LETGS

NARCIS (Netherlands)

Costantini, E.; Kaastra, J.S.; Arav, N.; Kriss, G.A.; Steenbrugge, K.C.; Gabel, J.R.; Verbunt, F.W.M.; Behar, E.; Gaskell, C. Martin; Korista, K.T.; Proga, D.; Kim Quijano, J.; Scott, J.E.; Klimek, E.S.; Hedrick, C.H.

2007-01-01

We present a Chandra-LETGS observation of the Seyfert 1 galaxy Mrk 279. This observation was simultaneous with HST-STIS and FUSE observations, in the context of a multiwavelength study of this source. The data also allow for the presence of intermediate ionization components. The distribution of the

New observational constraints on the growth of the first supermassive black holes

International Nuclear Information System (INIS)

Treister, E.; Schawinski, K.; Volonteri, M.; Natarajan, P.

2013-01-01

We constrain the total accreted mass density in supermassive black holes at z > 6, inferred via the upper limit derived from the integrated X-ray emission from a sample of photometrically selected galaxy candidates. Studying galaxies obtained from the deepest Hubble Space Telescope images combined with the Chandra 4 Ms observations of the Chandra Deep Field-South, we achieve the most restrictive constraints on total black hole growth in the early universe. We estimate an accreted mass density <1000 M ☉ Mpc –3 at z ∼ 6, significantly lower than the previous predictions from some existing models of early black hole growth and earlier prior observations. These results place interesting constraints on early black hole growth and mass assembly by accretion and imply one or more of the following: (1) only a fraction of the luminous galaxies at this epoch contain active black holes; (2) most black hole growth at early epochs happens in dusty and/or less massive—as yet undetected—host galaxies; (3) there is a significant fraction of low-z interlopers in the galaxy sample; (4) early black hole growth is radiatively inefficient, heavily obscured, and/or due to black hole mergers as opposed to accretion; or (5) the bulk of the black hole growth occurs at late times. All of these possibilities have important implications for our understanding of high-redshift seed formation models.

The Chandra Source Catalog: Source Properties and Data Products

Science.gov (United States)

Rots, Arnold; Evans, Ian N.; Glotfelty, Kenny J.; Primini, Francis A.; Zografou, Panagoula; Anderson, Craig S.; Bonaventura, Nina R.; Chen, Judy C.; Davis, John E.; Doe, Stephen M.; Evans, Janet D.; Fabbiano, Giuseppina; Galle, Elizabeth C.; Gibbs, Danny G., II; Grier, John D.; Hain, Roger; Hall, Diane M.; Harbo, Peter N.; He, Xiang Qun (Helen); Houck, John C.; Karovska, Margarita; Kashyap, Vinay L.; Lauer, Jennifer; McCollough, Michael L.; McDowell, Jonathan C.; Miller, Joseph B.; Mitschang, Arik W.; Morgan, Douglas L.; Mossman, Amy E.; Nichols, Joy S.; Nowak, Michael A.; Plummer, David A.; Refsdal, Brian L.; Siemiginowska, Aneta L.; Sundheim, Beth A.; Tibbetts, Michael S.; van Stone, David W.; Winkelman, Sherry L.

2009-09-01

The Chandra Source Catalog (CSC) is breaking new ground in several areas. There are two aspects that are of particular interest to the users: its evolution and its contents. The CSC will be a living catalog that becomes richer, bigger, and better in time while still remembering its state at each point in time. This means that users will be able to take full advantage of new additions to the catalog, while retaining the ability to back-track and return to what was extracted in the past. The CSC sheds the limitations of flat-table catalogs. Its sources will be characterized by a large number of properties, as usual, but each source will also be associated with its own specific data products, allowing users to perform mini custom analysis on the sources. Source properties fall in the spatial (position, extent), photometric (fluxes, count rates), spectral (hardness ratios, standard spectral fits), and temporal (variability probabilities) domains, and are all accompanied by error estimates. Data products cover the same coordinate space and include event lists, images, spectra, and light curves. In addition, the catalog contains data products covering complete observations: event lists, background images, exposure maps, etc. This work is supported by NASA contract NAS8-03060 (CXC).

Ferro-based derivatizing agents for LC/MS an LC/EC/MS

NARCIS (Netherlands)

Seiwert, Bettina

2007-01-01

Within this thesis, the development and application of ferrocene-based derivatizing agents for LC/MS and LC/EC/MS is presented. The advantages of derivatization by ferrocenes are the similtaneous introduction of a mass tag and an electroactive group, which make them ideally suited for LC/MS and

Analysis of foundation type alternative and deep-excavation on candidate site location of Panjang Island, Serang

International Nuclear Information System (INIS)

Heri Syaeful; June Mellawati

2013-01-01

Panjang Island is one of the alternatives location which is being studied as NPP site candidate. Its soil surface dominated by sand and eggshell deposit to the depth of tens of meter, beside that also the interlayer of sand and clay to the depth of 120 m. Purpose of the research is to analyze the alternative of foundation type and simulation of deep-excavation during foundation construction especially related to the slope stability aspect. The methods includes data collection of the analysis result of soil/rock mechanical laboratory, measurement of shear wave velocity by PS logging method, and analysis of alternative foundation type and deep-excavation. The analysis result of foundation type that can be applied on Panjang Island candidate site is combination of raft and pile foundation. Rock with Vs > 400 m/s in depth of 44 meter could be made as base of raft foundation construction. In the bottom it connected to pile foundation which is constructed to base rock in the depth of 120 m in Vs > 900 m/s. The result of slope stability analysis on deep-excavation with slope height of 44 m, vertical angle, on normal condition yield safety factor of 0,184 and on the condition of seismic load 0,138. Simulation of anchor installation with spacing 1.25 m as much as 15 pieces yield safety factor higher than 1.0 m. (author)

Searches for 3.5 keV Absorption Features in Cluster AGN Spectra

Science.gov (United States)

Conlon, Joseph P.

2018-06-01

We investigate possible evidence for a spectral dip around 3.5 keV in central cluster AGNs, motivated by previous results for archival Chandra observations of the Perseus cluster and the general interest in novel spectral features around 3.5 keV that may arise from dark matter physics. We use two deep Chandra observations of the Perseus and Virgo clusters that have recently been made public. In both cases, mild improvements in the fit (Δχ2 = 4.2 and Δχ2 = 2.5) are found by including such a dip at 3.5 keV into the spectrum. A comparable result (Δχ2 = 6.5) is found re-analysing archival on-axis Chandra ACIS-S observations of the centre of the Perseus cluster.

Adaptation to the deep-sea hydrothermal vents and cold seeps: Insights from the transcriptomes of Alvinocaris longirostris in both environments

Science.gov (United States)

Hui, Min; Cheng, Jiao; Sha, Zhongli

2018-05-01

Alvinocaris longirostris Kikuchi and Ohta, 1995 is one of the few species co-distributed in deep-sea hydrothermal vent and cold seep environments. We performed the transcriptome analysis for A. longirostris and identified differentially expressed genes (DEGs) between samples from the Iheya North hydrothermal vent (HV) and a methane seep in the South China Sea (MS). From the 57,801 annotated unigenes, multi-copies of enzyme family members for eliminating toxic xenobiotics were isolated and seven putatively duplicated gene clusters of cytochrome P450s were discovered, which may contribute to adaptation to the harsh conditions. Eight single amino acid substitutions of a Rhodopsin gene with low expression in two deep-sea alvinocaridid species were positively selected when compared with shallow water shrimps, which may be the result of adaptation to the dim-light environment in deep sea. 408 DEGs were identified with 53 and 355 up-regulated in HV and MS, respectively. Various genes associated with sulfur metabolism, detoxification and mitochondria were included, revealing different mechanisms of adaptation to the two types of extreme environments. All results are expected to serve as important basis for the further study.

Application of CE-ICP-MS and CE-ESI-MS/MS for identification of Zn-binding ligands in Goji berries extracts.

Science.gov (United States)

Ruzik, Lena; Kwiatkowski, Piotr

2018-06-01

The identification of groups of ligands binding metals is a crucial issue for the better understanding of their bioaccessibility. In the current study, we have intended an approach for identification of Zn-binding ligands based on using capillary electrophoresis combined with inductively coupled plasma mass spectrometry (CE-ICP-MS) and tandem electrospray ionization mass spectrometry (CE-ESI-MS/MS). The approach, which featured the use of the coupling of capillary electrophoresis with inductively coupled plasma mass spectrometry allows to separate and observe zinc ions present in complexes with respect to their size and charge and to identify nine compounds with zinc isotopic profile. CE-ICP-MS provides us with information about presence of zinc species and elemental information about zinc distribution. CE-ESI-MS/MS provide us with information about the most favorable Zn binding ligands: amino acids, flavonols, stilbenoids, fenolic acids and carotenoids. The presented work is the continuation of previous studies based on using LC-ESI-MS/MS, though, now we presented a new solutions with the possibility of changing detectors without changing the separation techniques, what is important without re-optimizing the method. The new presented method allows to identify the zinc-binding ligands in shorter time. Copyright © 2018 Elsevier B.V. All rights reserved.

Analysis of pesticide residues in strawberries and soils by GC-MS/MS, LC-MS/MS and two-dimensional GC-time-of-flight MS comparing organic and integrated pest management farming.

Science.gov (United States)

Fernandes, Virgínia C; Lehotay, Steven J; Geis-Asteggiante, Lucía; Kwon, Hyeyoung; Mol, Hans G J; van der Kamp, Henk; Mateus, Nuno; Domingues, Valentina F; Delerue-Matos, Cristina

2014-01-01

This study analysed 22 strawberry and soil samples after their collection over the course of 2 years to compare the residue profiles from organic farming with integrated pest management practices in Portugal. For sample preparation, we used the citrate-buffered version of the quick, easy, cheap, effective, rugged, and safe (QuEChERS) method. We applied three different methods for analysis: (1) 27 pesticides were targeted using LC-MS/MS; (2) 143 were targeted using low pressure GC-tandem mass spectrometry (LP-GC-MS/MS); and (3) more than 600 pesticides were screened in a targeted and untargeted approach using comprehensive, two-dimensional gas chromatography time-of-flight mass spectrometry (GC × GC-TOF-MS). Comparison was made of the analyses using the different methods for the shared samples. The results were similar, thereby providing satisfactory confirmation of both similarly positive and negative findings. No pesticides were found in the organic-farmed samples. In samples from integrated pest management practices, nine pesticides were determined and confirmed to be present, ranging from 2 µg kg(-1) for fluazifop-p-butyl to 50 µg kg(-1) for fenpropathrin. Concentrations of residues in strawberries were less than European maximum residue limits.

Quantitative Determination of Perfluorochemicals and Fluorotelomer Alcohols in Plants from Biosolid-Amended Fields using LC/MS/MS and GC/MS

Science.gov (United States)

Analytical methods for determining perfluorochemicals (PFCs) and fluorotelomer alcohols (FTOHs) in plants using liquid chromatography/tandem mass spectrometry (LC/MS/MS) and gas chromatography/mass spectrometry (GC/MS) were developed, and applied to quantify a suite of analytes i...

In Vivo Metabolism Study of Xiamenmycin A in Mouse Plasma by UPLC-QTOF-MS and LC-MS/MS

Directory of Open Access Journals (Sweden)

Feng Lei

2015-01-01

Full Text Available Xiamenmycin A is an antifibrotic leading compound with a benzopyran skeleton that is isolated from mangrove-derived Streptomyces xiamenensis. As a promising small molecule for fibrotic diseases, less information is known about its metabolic characteristics in vivo. In this study, the time-course of xiamenmycin A in mouse plasma was investigated by relative quantification. After two types of administration of xiamenmycin A at a single dose of 10 mg/kg, the plasma concentrations were measured quantitatively by LC-MS/MS. The dynamic changes in the xiamenmycin A concentration showed rapid absorption and quick elimination in plasma post-administration. Four metabolites (M1–M4 were identified in blood by UPLC-QTOF-MS, and xiamenmycin B (M3 is the principal metabolite in vivo, as verified by comparison of the authentic standard sample. The structures of other metabolites were identified based on the characteristics of their MS and MS/MS data. The newly identified metabolites are useful for understanding the metabolism of xiamenmycin A in vivo, aiming at the development of an anti-fibrotic drug candidate for the therapeutic treatment of excessive fibrotic diseases.

Relapsing-Remitting MS (RRMS)

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Chandra reveals a black hole X-ray binary within the ultraluminous supernova remnant MF 16

Science.gov (United States)

Roberts, T. P.; Colbert, E. J. M.

2003-06-01

We present evidence, based on Chandra ACIS-S observations of the nearby spiral galaxy NGC 6946, that the extraordinary X-ray luminosity of the MF 16 supernova remnant actually arises in a black hole X-ray binary. This conclusion is drawn from the point-like nature of the X-ray source, its X-ray spectrum closely resembling the spectrum of other ultraluminous X-ray sources thought to be black hole X-ray binary systems, and the detection of rapid hard X-ray variability from the source. We briefly discuss the nature of the hard X-ray variability, and the origin of the extreme radio and optical luminosity of MF 16 in light of this identification.

Chandra Observations of a Collisionally and Optically Thin Charge Exchange System - Comet 2P/Encke 2003

Science.gov (United States)

Christian, D. J.; Lisse, C. M.; Dennerl, K.; Wolk, S. J.; Bodewits, D.; Combi, M. R.; Hoekstra, R.; Makinen, J. T. T.; Weaver, H. A.

2004-11-01

The highly favorable perigee passage of the x-ray bright comet 2P/Encke in late 2003 provided an excellent opportunity to use Chandra's high spatial, spectral, and temporal resolution to study cometary x-ray emission in the low neutral target density, low x-ray flux regime. The 1997 ROSAT/EUVE observations of Encke (Lisse et al. 1999) and the nucleus rotation studies of Luu and Jewitt (1990, most likely rotation period = 15 hours) suggested a simple Chandra experiment - continuous ACIS-S observations of Encke over 15 hours during the time of its closest approach to Earth. Here we report initial results from our X-ray observations. X-ray emission from comet Encke was found only in a small, asymmetric region between 1500 km - 40,000 km from the nucleus. The Encke ACIS-S3 200 -- 1000 eV spectrum shows many of the same x-ray emission lines previously observed from comets (C+5, O+6,O+7), including confirmation of several emission lines in the 800 to 1000 eV range. However, the Encke spectrum shows very different line ratios in the 200 - 700 eV range than any previous comet. A lightcurve with peak-to-peak amplitude of 20% and period 11.7 hours was found over the 15 hour observing period. Comparing the observations to contemporaneous measurements of the coma and solar wind made by other means, we find the combination of a low density, collisionally thin (to charge exchange) coma and a post-massive X-flare, high temperature, moderate density solar wind can explain our unusual Encke x-ray observations.

CHANDRA OBSERVATIONS OF COMETS C/2012 S1 (ISON) AND C/2011 L4 (PanSTARRS)

Energy Technology Data Exchange (ETDEWEB)

Snios, Bradford; Kharchenko, Vasili [Department of Physics, University of Connecticut, Storrs, CT 06269 (United States); Lisse, Carey M. [Planetary Exploration Group, Space Department, Johns Hopkins University Applied Physics Laboratory, Laurel, MD 20723 (United States); Wolk, Scott J. [Chandra X-Ray Observatory Center, Harvard-Smithsonian Center for Astrophysics, Cambridge, MA 02138 (United States); Dennerl, Konrad [Max-Planck-Institut für extraterrestrische Physik, D-85748 Garching (Germany); Combi, Michael R. [Department of Climate and Space Sciences and Engineering, University of Michigan, Ann Arbor, MI 48109 (United States)

2016-02-20

We present our results on the Chandra X-ray Observatory Advanced CCD Imaging Spectrometer (ACIS) observations of the bright Oort Cloud comets C/2012 S1 (ISON) and C/2011 L4 (PanSTARRS). ISON was observed between 2013 October 31–November 06 during variable speed solar wind (SW), and PanSTARRS was observed between 2013 April 17–23 during fast SW. ISON produced an extended parabolic X-ray morphology consistent with a collisionally thick coma, while PanSTARRS demonstrated only a diffuse X-ray-emitting region. We consider these emissions to be from charge exchange (CX) and model each comet's emission spectrum from first principles accordingly. Our model agrees with the observational spectra and also generates composition ratios for heavy, highly charged SW ions interacting with the cometary atmosphere. We compare our derived SW ion compositions to observational data and find a strong agreement between them. These results further demonstrate the utility of CX emissions as a remote diagnostics tool of both astrophysical plasma interaction and SW composition. In addition, we observe potential soft X-ray emissions via ACIS around 0.2 keV from both comets that are correlated in intensity to the hard X-ray emissions between 0.4–1.0 keV. We fit our CX model to these emissions, but our lack of a unique solution at low energies makes it impossible to conclude if they are cometary CX in origin. Finally, we discuss probable emission mechanism sources for the soft X-rays and explore new opportunities these findings present in understanding cometary emission processes via Chandra.

Survey of diagnostic and treatment practices for multiple sclerosis (MS) in Europe. Part 2: Progressive MS, paediatric MS, pregnancy and general management.

Science.gov (United States)

Fernández, O; Delvecchio, M; Edan, G; Fredrikson, S; Giovannoni, G; Hartung, H-P; Havrdova, E; Kappos, L; Pozzilli, C; Soerensen, P S; Tackenberg, B; Vermersch, P; Comi, G

2018-05-01

The European Charcot Foundation supported the development of a set of surveys to understand current practice patterns for the diagnosis and management of multiple sclerosis (MS) in Europe. Part 2 of the report summarizes survey results related to secondary progressive MS (SPMS), primary progressive MS (PPMS), pregnancy, paediatric MS and overall patient management. A steering committee of MS neurologists developed case- and practice-based questions for two sequential surveys distributed to MS neurologists throughout Europe. Respondents generally favoured changing rather than stopping disease-modifying treatment (DMT) in patients transitioning from relapsing-remitting MS to SPMS, particularly with active disease. Respondents would not initiate DMT in patients with typical PPMS symptoms, although the presence of ≥1 spinal cord or brain gadolinium-enhancing lesion might affect that decision. For patients considering pregnancy, respondents were equally divided on whether to stop treatment before or after conception. Respondents strongly favoured starting DMT in paediatric MS with active disease; recommended treatments included interferon, glatiramer acetate and, in John Cunningham virus negative patients, natalizumab. Additional results regarding practice-based questions and management are summarized. Results of part 2 of the survey of diagnostic and treatment practices for MS in Europe largely mirror results for part 1, with neurologists in general agreement about the treatment and management of SPMS, PPMS, pregnancy and paediatric MS as well as the general management of MS. However, there are also many areas of disagreement, indicating the need for evidence-based recommendations and/or guidelines. © 2018 EAN.

Cometary X-rays - the View After the First Chandra Cycle

Science.gov (United States)

Lisse, Carey M.

2001-09-01

The unexpected discovery of x-ray emission from Comet Hyakutake in March 1996 (Lisse et al. 1996) has produced a number of questions about the physical mechanism producing the radiation. The original detection and subsequent observations (Dennerl et al. 1997, Mumma et al. 1997, Krasnopolsky et al. 1998, Owens et al. 1998, Lisse et al. 1999) have shown that the very soft (best fit thermal bremsstrahlung model kT 0.2 keV) emission is due to an interaction between the solar wind and the comet's atmosphere. Using the results from the 15 comets detected to date in x-rays, we report on the latest results on cometary x-ray emission, including new results from Chandra and XMM. As-observed morphologies, spectra, and light curves will be discussed. Our emphasis will be on understanding the physical mechanism producing the emission, and using this to determine the nature of the cometary coma, the structure of the solar wind in the heliosphere, and the source of the local soft x-ray background. This work has been graciously supported by grants from the NASA Planetary Astronomy and Astrophysical Data Programs.

Sulphur fertilization influences the sulphur species composition in Allium sativum: sulphomics using HPLC-ICPMS/MS-ESI-MS/MS.

Science.gov (United States)

Raab, Andrea; Ronzan, Marilena; Feldmann, Joerg

2017-10-18

Garlic (A. sativum) contains a large number of small sulphur (S)-containing metabolites, which are important for its taste and smell and vary with A. sativum variety and growth conditions. This study was designed to investigate the influence of different sulphur-fertilization regimes on low molecular weight S-species by attempting the first sulphur mass balance in A. sativum roots and bulbs using HPLC-ICPMS/MS-ESI-MS/MS. Species unspecific quantification of acid soluble S-containing metabolites was achieved using HPLC-ICP-MS/MS. For identification of the compounds, high resolution ESI-MS (Orbitrap LTQ and q-TOF) was used. The plants contained up to 54 separated sulphur-containing compounds, which constitute about 80% of the total sulphur present in A. sativum. The roots and bulbs of A. sativum contained the same compounds, but not necessarily the same amounts and proportions. The S-containing metabolites in the roots reacted more sensitively to manipulations of sulphur fertilization than those compounds in the bulbs. In addition to known compounds (e.g. γ-glutamyl-S-1-propenylcysteine) we were able to identify and partially quantify 31 compounds. Three as yet undescribed S-containing compounds were also identified and quantified for the first time. Putative structures were assigned to the oxidised forms of S-1-propenylmercaptoglutathione, S-2-propenylmercaptoglutathione, S-allyl/propenyl-containing PC-2 and 2-amino-3-[(2-carboxypropyl)sulfanyl]propanoic acid. The parallel use of ICP-MS/MS as a sulphur-specific detector and ESI-MS as a molecular detector simplifies the identification and quantification of sulphur containing metabolites without species specific standards. This non-target analysis approach enables a mass balance approach and identifies the occurrence of the so far unidentified organosulphur compounds. The experiments showed that the sulphur-fertilization regime does not influence sulphur-speciation, but the concentration of some S

Characterization, stoichiometry, and stability of salivary protein-tannin complexes by ESI-MS and ESI-MS/MS.

Science.gov (United States)

Canon, Francis; Paté, Franck; Meudec, Emmanuelle; Marlin, Thérèse; Cheynier, Véronique; Giuliani, Alexandre; Sarni-Manchado, Pascale

2009-12-01

Numerous protein-polyphenol interactions occur in biological and food domains particularly involving proline-rich proteins, which are representative of the intrinsically unstructured protein group (IUP). Noncovalent protein-ligand complexes are readily detected by electrospray ionization mass spectrometry (ESI-MS), which also gives access to ligand binding stoichiometry. Surprisingly, the study of interactions between polyphenolic molecules and proteins is still an area where ESI-MS has poorly benefited, whereas it has been extensively applied to the detection of noncovalent complexes. Electrospray ionization mass spectrometry has been applied to the detection and the characterization of the complexes formed between tannins and a human salivary proline-rich protein (PRP), namely IB5. The study of the complex stability was achieved by low-energy collision-induced dissociation (CID) measurements, which are commonly implemented using triple quadrupole, hybrid quadrupole time-of-flight, or ion trap instruments. Complexes composed of IB5 bound to a model polyphenol EgCG have been detected by ESI-MS and further analyzed by MS/MS. Mild ESI interface conditions allowed us to observe intact noncovalent PRP-tannin complexes with stoichiometries ranging from 1:1 to 1:5. Thus, ESI-MS shows its efficiency for (1) the study of PRP-tannin interactions, (2) the determination of stoichiometry, and (3) the study of complex stability. We were able to establish unambiguously both their stoichiometries and their overall subunit architecture via tandem mass spectrometry and solution disruption experiments. Our results prove that IB5.EgCG complexes are maintained intact in the gas phase.

Determination of αs and mc in deep-inelastic scattering

International Nuclear Information System (INIS)

Alekhin, Sergey; Bluemlein, Johannes; Moch, Sven-Olaf

2013-07-01

We describe the determination of the strong coupling constant α s (M Z 2 ) and of the charm-quark mass m c (m c ) in the MS-scheme, based on the QCD analysis of the unpolarized World deep-inelastic scattering data. At NNLO the values of α s (M Z 2 )=0.1134±0.001(exp) and m c (m c )=1.24±0.03(exp) +0.03 -0.02 (scale) +0.00 -0.07 (th) are obtained and are compared with other determinations, also clarifying discrepancies.

An improved method of sample preparation on AnchorChip targets for MALDI-MS and MS/MS and its application in the liver proteome project

DEFF Research Database (Denmark)

Zhang, Xumin; Shi, Liang; Shu, Shaokung

2007-01-01

An improved method for sample preparation for MALDI-MS and MS/MS using AnchorChip targets is presented. The method, termed the SMW method (sample, matrix wash), results in better sensitivity for peptide mass fingerprinting as well as for sequencing by MS/MS than previously published methods. The ...

An Archival Chandra and XMM-Newton Survey of Type 2 Quasars

Science.gov (United States)

Jia, Jianjun; Ptak, Andrew Francis; Heckman, Timothy; Zakamska, Nadia L.

2013-01-01

In order to investigate obscuration in high-luminosity type 2 active galactic nuclei (AGNs), we analyzed Chandra and XMM-Newton archival observations for 71 type 2 quasars detected at 0.05 100 eV in the rest frame) and we detect this line in the other sources through a joint fit (spectral stacking). The correlation between the Fe K alpha and [O III] fluxes and the inverse correlation of the equivalent width of the Fe Ka line with the ratio of hard X-ray and [O III] fluxes is consistent with previous results for lower luminosity Seyfert 2 galaxies. We conclude that obscuration is the cause of the weak hard X-ray emission rather than intrinsically low X-ray luminosities. We find that about half of the population of optically selected type 2 quasars are likely to be Compton thick. We also find no evidence that the amount of X-ray obscuration depends on the AGN luminosity (over a range of more than three orders of magnitude in luminosity).

Discovery of X-Ray Emission from the Crab Pulsar at Pulse Minimum

Science.gov (United States)

Tennant, Allyn F.; Becker, Werner; Juda, Michael; Elsner, Ronald F.; Kolodziejczak, Jeffery J.; Murray, Stephen S.; ODell, Stephen L.; Paerels, Frits; Swartz, Douglas A.

2001-01-01

The Chandra X-Ray Observatory observed the Crab pulsar using the Low-Energy Transmission Grating with the High-Resolution Camera. Time-resolved zeroth-order images reveal that the pulsar emits X-rays at all pulse phases. Analysis of the flux at minimum - most likely non-thermal in origin - places an upper limit (T(sub infinity) < 2.1 MK) on the surface temperature of the underlying neutron star. In addition, analysis of the pulse profile establishes that the error in the Chandra-determined absolute time is quite small, -0.2 +/- 0.1 ms.

Relapsing-Remitting MS (RRMS)

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Full Text Available ... for You and Your Practice Publications for Clinicians Publications for Your Patients MS Navigator Program Programs and Services for Your Patients ... Relapsing-remitting MS (RRMS) Relapsing-remitting MS ( ...

An in silico MS/MS library for automatic annotation of novel FAHFA lipids.

Science.gov (United States)

Ma, Yan; Kind, Tobias; Vaniya, Arpana; Gennity, Ingrid; Fahrmann, Johannes F; Fiehn, Oliver

2015-01-01

A new lipid class named 'fatty acid esters of hydroxyl fatty acids' (FAHFA) was recently discovered in mammalian adipose tissue and in blood plasma and some FAHFAs were found to be associated with type 2 diabetes. To facilitate the automatic annotation of FAHFAs in biological specimens, a tandem mass spectra (MS/MS) library is needed. Due to the limitation of the commercial available standard compounds, we proposed building an in silico MS/MS library to extend the coverage of molecules. We developed a computer-generated library with 3267 tandem mass spectra (MS/MS) for 1089 FAHFA species. FAHFA spectra were generated based on authentic standards with negative mode electrospray ionization and 10, 20, and 40 V collision induced dissociation at 4 spectra/s as used in in ultra-high performance liquid chromatography-QTOF mass spectrometry studies. However, positional information of the hydroxyl group is only obtained either at lower QTOF spectra acquisition rates of 1 spectrum/s or at the MS(3) level in ion trap instruments. Therefore, an additional set of 4290 fragment-rich MS/MS spectra was created to enable distinguishing positional FAHFA isomers. The library was generated based on ion fragmentations and ion intensities of FAHFA external reference standards, developing a heuristic model for fragmentation rules and extending these rules to large swaths of computer-generated structures of FAHFAs with varying chain lengths, degrees of unsaturation and hydroxyl group positions. Subsequently, we validated the new in silico library by discovering several new FAHFA species in egg yolk, showing that this library enables high-throughput screening of FAHFA lipids in various biological matrices. The developed library and templates are freely available for commercial or noncommercial use at http://fiehnlab.ucdavis.edu/staff/yanma/fahfa-lipid-library. This in silico MS/MS library allows users to annotate FAHFAs from accurate mass tandem mass spectra in an easy and fast manner

Structure Elucidation of Unknown Metabolites in Metabolomics by Combined NMR and MS/MS Prediction.

Science.gov (United States)

Boiteau, Rene M; Hoyt, David W; Nicora, Carrie D; Kinmonth-Schultz, Hannah A; Ward, Joy K; Bingol, Kerem

2018-01-17

We introduce a cheminformatics approach that combines highly selective and orthogonal structure elucidation parameters; accurate mass, MS/MS (MS²), and NMR into a single analysis platform to accurately identify unknown metabolites in untargeted studies. The approach starts with an unknown LC-MS feature, and then combines the experimental MS/MS and NMR information of the unknown to effectively filter out the false positive candidate structures based on their predicted MS/MS and NMR spectra. We demonstrate the approach on a model mixture, and then we identify an uncatalogued secondary metabolite in Arabidopsis thaliana . The NMR/MS² approach is well suited to the discovery of new metabolites in plant extracts, microbes, soils, dissolved organic matter, food extracts, biofuels, and biomedical samples, facilitating the identification of metabolites that are not present in experimental NMR and MS metabolomics databases.

Analytical Method Details (MS): SE53_MS03 [Metabolonote[Archive

Lifescience Database Archive (English)

Full Text Available SE53_MS03 CE-TOF/MS Agilent CE capillary electrophoresis system,Agilent G3250AA LC/...s were performed using an Agilent CE capillary electrophoresis system (Agilent Technologies, Waldbronn, Germ

Quality evaluation of LC-MS/MS-based E. coli H antigen typing (MS-H) through label-free quantitative data analysis in a clinical sample setup.

Science.gov (United States)

Cheng, Keding; Sloan, Angela; McCorrister, Stuart; Peterson, Lorea; Chui, Huixia; Drebot, Mike; Nadon, Celine; Knox, J David; Wang, Gehua

2014-12-01

The need for rapid and accurate H typing is evident during Escherichia coli outbreak situations. This study explores the transition of MS-H, a method originally developed for rapid H antigen typing of E. coli using LC-MS/MS of flagella digest of reference strains and some clinical strains, to E. coli isolates in clinical scenario through quantitative analysis and method validation. Motile and nonmotile strains were examined in batches to simulate clinical sample scenario. Various LC-MS/MS batch run procedures and MS-H typing rules were compared and summarized through quantitative analysis of MS-H data output for a standard method development. Label-free quantitative data analysis of MS-H typing was proven very useful for examining the quality of MS-H result and the effects of some sample carryovers from motile E. coli isolates. Based on this, a refined procedure and protein identification rule specific for clinical MS-H typing was established and validated. With LC-MS/MS batch run procedure and database search parameter unique for E. coli MS-H typing, the standard procedure maintained high accuracy and specificity in clinical situations, and its potential to be used in a clinical setting was clearly established. © 2014 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Multi-Segment Direct Inject nano-ESI-LTQ-FT-ICR-MS/MS For Protein Identification

Directory of Open Access Journals (Sweden)

Neal Rachel E

2011-07-01

Full Text Available Abstract Reversed phase high performance liquid chromatography (HPLC interfaced to electrospray tandem mass spectrometry (MS/MS is commonly used for the identification of peptides from proteolytically cleaved proteins embedded in a polyacrylamide gel matrix as well as for metabolomics screening. HPLC separations are time consuming (30-60 min average, costly (columns and mobile phase reagents, and carry the risk of column carry over between samples. The use of a chip-based nano-ESI platform (Advion NanoMate based on replaceable nano-tips for sample introduction eliminates sample cross-contamination, provides unchanging sample matrix, and enhances spray stability with attendant increases in reproducibility. Recent papers have established direct infusion nano-ESI-MS/MS utilizing the NanoMate for protein identification of gel spots based on full range MS scans with data dependent MS/MS. In a full range scan, discontinuous ion suppression due to sample matrix can impair identification of putative mass features of interest in both the proteomic and metabolomic workflows. In the current study, an extension of an established direct inject nano-ESI-MS/MS method is described that utilizes the mass filtering capability of an ion-trap for ion packet separation into four narrow mass ranges (50 amu overlap with segment specific dynamic data dependent peak inclusion for MS/MS fragmentation (total acquisition time of 3 minutes. Comparison of this method with a more traditional nanoLC-MS/MS based protocol utilizing solvent/sample stream splitting to achieve nanoflow demonstrated comparable results for protein identification from polyacrylamide gel matrices. The advantages of this method include full automation, lack of cross-contamination, low cost, and high throughput.

DEEP CHANDRA, HST-COS, AND MEGACAM OBSERVATIONS OF THE PHOENIX CLUSTER: EXTREME STAR FORMATION AND AGN FEEDBACK ON HUNDRED KILOPARSEC SCALES

International Nuclear Information System (INIS)

McDonald, Michael; Bautz, Marshall W.; Miller, Eric D.; ZuHone, John A.; McNamara, Brian R.; Weeren, Reinout J. van; Bayliss, Matthew; Jones-Forman, Christine; Applegate, Douglas E.; Benson, Bradford A.; Carlstrom, John E.; Mantz, Adam B.; Bleem, Lindsey E.; Chatzikos, Marios; Edge, Alastair C.; Fabian, Andrew C.; Garmire, Gordon P.; Hlavacek-Larrondo, Julie; Stalder, Brian; Veilleux, Sylvain

2015-01-01

We present new ultraviolet, optical, and X-ray data on the Phoenix galaxy cluster (SPT-CLJ2344-4243). Deep optical imaging reveals previously undetected filaments of star formation, extending to radii of ∼50–100 kpc in multiple directions. Combined UV-optical spectroscopy of the central galaxy reveals a massive (2 × 10 9 M ⊙ ), young (∼4.5 Myr) population of stars, consistent with a time-averaged star formation rate of 610 ± 50 M ⊙ yr −1 . We report a strong detection of O vi λλ1032,1038, which appears to originate primarily in shock-heated gas, but may contain a substantial contribution (>1000 M ⊙ yr −1 ) from the cooling intracluster medium (ICM). We confirm the presence of deep X-ray cavities in the inner ∼10 kpc, which are among the most extreme examples of radio-mode feedback detected to date, implying jet powers of 2–7 × 10 45 erg s −1 . We provide evidence that the active galactic nucleus inflating these cavities may have only recently transitioned from “quasar-mode” to “radio-mode,” and may currently be insufficient to completely offset cooling. A model-subtracted residual X-ray image reveals evidence for prior episodes of strong radio-mode feedback at radii of ∼100 kpc, with extended “ghost” cavities indicating a prior epoch of feedback roughly 100 Myr ago. This residual image also exhibits significant asymmetry in the inner ∼200 kpc (0.15R 500 ), reminiscent of infalling cool clouds, either due to minor mergers or fragmentation of the cooling ICM. Taken together, these data reveal a rapidly evolving cool core which is rich with structure (both spatially and in temperature), is subject to a variety of highly energetic processes, and yet is cooling rapidly and forming stars along thin, narrow filaments

Revisiting the Short-term X-ray Spectral Variability of NGC 4151 with Chandra

Science.gov (United States)

Wang, Junfeng; Risaliti, G.; Fabbiano, G.; Elvis, M.; Zezas, A.; Karovska, M.

2010-05-01

We present new X-ray spectral data for the Seyfert 1 nucleus in NGC 4151 observed with Chandra for ~200 ks. A significant ACIS pileup is present, resulting in a nonlinear count rate variation during the observation. With pileup corrected spectral fitting, we are able to recover the spectral parameters and find consistency with those derived from unpiled events in the ACIS readout streak and outer region from the bright nucleus. The absorption corrected 2-10 keV flux of the nucleus varied between 6 × 10-11 erg s-1 cm-2 and 10-10 erg s-1 cm-2 (L 2-10 keV ~ 1.3-2.1 × 1042 erg s-1). Similar to earlier Chandra studies of NGC 4151 at a historical low state, the photon indices derived from the same absorbed power-law model are Γ ~ 0.7-0.9. However, we show that Γ is highly dependent on the adopted spectral models. Fitting the power-law continuum with a Compton reflection component gives Γ ~ 1.1. By including passage of non-uniform X-ray obscuring clouds, we can reproduce the apparent flat spectral states with Γ ~ 1.7, typical for Seyfert 1 active galactic nuclei. The same model also fits the hard spectra from previous ASCA "long look" observation of NGC 4151 in the lowest flux state. The spectral variability during our observation can be interpreted as variations in intrinsic soft continuum flux relative to a Compton reflection component that is from distant cold material and constant on short timescale, or variations of partially covering absorber in the line of sight toward the nucleus. An ionized absorber model with ionization parameter log ξ ~ 0.8-1.1 can also fit the low-resolution ACIS spectra. If the partial covering model is correct, adopting a black hole mass M_{BH}˜ 4.6× 10^7 M sun we constrain the distance of the obscuring cloud from the central black hole to be r <~ 9 lt-day, consistent with the size of the broad emission line region of NGC 4151 from optical reverberation mapping.

REVISITING THE SHORT-TERM X-RAY SPECTRAL VARIABILITY OF NGC 4151 WITH CHANDRA

International Nuclear Information System (INIS)

Wang Junfeng; Fabbiano, G.; Elvis, M.; Zezas, A.; Karovska, M.; Risaliti, G.

2010-01-01

We present new X-ray spectral data for the Seyfert 1 nucleus in NGC 4151 observed with Chandra for ∼200 ks. A significant ACIS pileup is present, resulting in a nonlinear count rate variation during the observation. With pileup corrected spectral fitting, we are able to recover the spectral parameters and find consistency with those derived from unpiled events in the ACIS readout streak and outer region from the bright nucleus. The absorption corrected 2-10 keV flux of the nucleus varied between 6 x 10 -11 erg s -1 cm -2 and 10 -10 erg s -1 cm -2 (L 2-10 k eV ∼ 1.3-2.1 x 10 42 erg s -1 ). Similar to earlier Chandra studies of NGC 4151 at a historical low state, the photon indices derived from the same absorbed power-law model are Γ ∼ 0.7-0.9. However, we show that Γ is highly dependent on the adopted spectral models. Fitting the power-law continuum with a Compton reflection component gives Γ ∼ 1.1. By including passage of non-uniform X-ray obscuring clouds, we can reproduce the apparent flat spectral states with Γ ∼ 1.7, typical for Seyfert 1 active galactic nuclei. The same model also fits the hard spectra from previous ASCA 'long look' observation of NGC 4151 in the lowest flux state. The spectral variability during our observation can be interpreted as variations in intrinsic soft continuum flux relative to a Compton reflection component that is from distant cold material and constant on short timescale, or variations of partially covering absorber in the line of sight toward the nucleus. An ionized absorber model with ionization parameter log ξ ∼ 0.8-1.1 can also fit the low-resolution ACIS spectra. If the partial covering model is correct, adopting a black hole mass M BH ∼4.6x10 7 M sun we constrain the distance of the obscuring cloud from the central black hole to be r ∼< 9 lt-day, consistent with the size of the broad emission line region of NGC 4151 from optical reverberation mapping.

Relapsing-Remitting MS (RRMS)

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Full Text Available ... Disease T Cells d What Causes MS? Disproved Theories Viruses Clusters d Who Gets MS? Pediatric MS ... times as often as men; in PPMS, the number of women and men are approximately equal. RRMS ...

Relapsing-Remitting MS (RRMS)

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Full Text Available ... Living Well with MS Diet, Exercise & Healthy Behaviors Emotional Well-Being Spiritual Well-Being Cognitive Health Work, ... MS Anesthesia and Surgery Managing Your MS d Emotional Well-Being Mood Changes d Spiritual Well-Being ...

Relapsing-Remitting MS (RRMS)

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Full Text Available ... Disease T Cells d What Causes MS? Disproved Theories Viruses Clusters d Who Gets MS? Pediatric MS ... of Distinction Lawry Circle Circle of Influence d Planned Giving d Other Ways to Give Donate by ...

Relapsing-Remitting MS (RRMS)

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Full Text Available ... Trials in MS Wellness and Lifestyle Research Diet Vitamin D How and Why Do Scientists Share Results ... The National MS Society is Here to Help Need More Information? We Are Here Our MS Navigators ...

Relapsing-Remitting MS (RRMS)

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Full Text Available ... Disease T Cells d What Causes MS? Disproved Theories Viruses Clusters d Who Gets MS? Pediatric MS ... Community at MSconnection.org Join a Local Support Group Peer Connections: One-on-One Edward M. Dowd ...

Relapsing-Remitting MS (RRMS)

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Full Text Available ... Disease T Cells d What Causes MS? Disproved Theories Viruses Clusters d Who Gets MS? Pediatric MS ... Review of Society's Research Programs d Careers d Leadership Board of Directors Senior Leadership Team Founder Sylvia ...

Relapsing-Remitting MS (RRMS)

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Full Text Available ... working effectively. How does RRMS differ from progressive types of MS? While RRMS is defined by attacks ... Pinterest MS Connection About the Society Vision Careers Leadership Cultural Values Financials News Press Room MS Prevalence ...

Relapsing-Remitting MS (RRMS)

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Relapsing-Remitting MS (RRMS)

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Full Text Available ... Disproved Theories Viruses Clusters d Who Gets MS? Pediatric MS African Americans Hispanics & Latino/as d Multiple ... Questions to Ask d Resources for Specific Populations Pediatric MS Support Veterans with Multiple Sclerosis d Find ...

Relapsing-Remitting MS (RRMS)

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Simultaneous analysis of 17 diuretics in dietary supplements by HPLC and LC-MS/MS.

Science.gov (United States)

Woo, H; Kim, J W; Han, K M; Lee, J H; Hwang, I S; Lee, J H; Kim, J; Kweon, S J; Cho, S; Chae, K R; Han, S Y; Kim, J

2013-01-01

In order to test health foods for illegally added diuretics for weight loss, we developed simple, rapid, selective, and sensitive methods using HPLC and LC-MS/MS for the simultaneous analysis of 17 diuretics in dietary supplements. HPLC conditions were set with a Capcell-pak C18, using a mobile phase consisting of gradient conditions, UV detection at 254 nm and validated for linearity (r(2)> 0.999), precision (CV ≤ 3%), recoveries (90.4-102.8%) and reproducibility. Identification and quantification of 17 diuretics were accomplished by ion-spray LC-MS/MS using multiple reaction monitoring (MRM). The chromatographic separation was carried out under the reversed-phase mechanism on an HSS-T3 column. The LC-MS/MS method was validated for linearity (r(2)> 0.99) and precision (CV Diuretics were not detected in all samples. Extraction recovery was also investigated and the extraction recoveries in different formulations were from 88% to 110% and from 81% to 116% using HPLC and LC-MS/MS, respectively. There was no significant difference in recoveries in the type of dietary supplements. Based on this result, the developed methods to monitor illegal drug adulterations in dietary supplements using HPLC and LC-MS/MS are simple, fast and reliable. Therefore, it is applicable to routine drug-adulteration screening.

Imaging AGN Feedback in NGC 3393 with CHEERS

Science.gov (United States)

Paggi, Alessandro; Maksym, W. Peter; Fabbiano, Giuseppina; Elvis, Martin; Karovska, Margarita; Wang, Junfeng; Storchi-Bergmann, Thaisa

2016-04-01

The CHandra Extended Emission-line Region Survey (CHEERS) is the 'ultimate' resolution X-ray imaging survey of nearby far-IR selected AGN. By comparing deep Chandra observations with complementary HST and radio data, we investigate the morphology of the extended narrow-line region on scales of <100 pc. We present new results on the gas surrounding the compton-thick AGN NGC 3393. The luminous extended narrow-line X-ray emission from this gas allows us to study the role and extent of AGN feedback as sub-kpc jets interact with the surrounding ISM.

Relapsing-Remitting MS (RRMS)

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Full Text Available ... Viruses Clusters d Who Gets MS? Pediatric MS African Americans Hispanics & Latino/as d Multiple Sclerosis FAQs d ... Diet & Nutrition Exercise Heat & Temperature Sensitivity Sleep Vaccinations Women's Health Unhealthy Habits Managing MS and Another Condition ...

A New Sensitive GC-MS-based Method for Analysis of Dipicolinic Acid and Quantifying Bacterial Endospores in Deep Marine Subsurface Sediment

Science.gov (United States)

Fang, J.

2015-12-01

Marine sediments cover more than two-thirds of the Earth's surface and represent a major part of the deep biosphere. Microbial cells and microbial activity appear to be widespread in these sediments. Recently, we reported the isolation of gram-positive anaerobic spore-forming piezophilic bacteria and detection of bacterial endospores in marine subsurface sediment from the Shimokita coalbed, Japan. However, the modern molecular microbiological methods (e.g., DNA-based microbial detection techniques) cannot detect bacterial endospore, because endospores are impermeable and are not stained by fluorescence DNA dyes or by ribosomal RNA staining techniques such as catalysed reporter deposition fluorescence in situ hybridization. Thus, the total microbial cell abundance in the deep biosphere may has been globally underestimated. This emphasizes the need for a new cultivation independent approach for the quantification of bacterial endospores in the deep subsurface. Dipicolinic acid (DPA, pyridine-2,6-dicarboxylic acid) is a universal and specific component of bacterial endospores, representing 5-15wt% of the dry spore, and therefore is a useful indicator and quantifier of bacterial endospores and permits to estimate total spore numbers in the subsurface biosphere. We developed a sensitive analytical method to quantify DPA content in environmental samples using gas chromatography-mass spectrometry. The method is sensitive and more convenient in use than other traditional methods. We applied this method to analyzing sediment samples from the South China Sea (obtained from IODP Exp. 349) to determine the abundance of spore-forming bacteria in the deep marine subsurface sediment. Our results suggest that gram-positive, endospore-forming bacteria may be the "unseen majority" in the deep biosphere.

Deep Echo State Network (DeepESN): A Brief Survey

OpenAIRE

Gallicchio, Claudio; Micheli, Alessio

2017-01-01

The study of deep recurrent neural networks (RNNs) and, in particular, of deep Reservoir Computing (RC) is gaining an increasing research attention in the neural networks community. The recently introduced deep Echo State Network (deepESN) model opened the way to an extremely efficient approach for designing deep neural networks for temporal data. At the same time, the study of deepESNs allowed to shed light on the intrinsic properties of state dynamics developed by hierarchical compositions ...

CHANDRA DETECTION OF A NEW DIFFUSE X-RAY COMPONENT FROM THE GLOBULAR CLUSTER 47 TUCANAE

Energy Technology Data Exchange (ETDEWEB)

Wu, E. M. H.; Cheng, K. S. [Department of Physics, University of Hong Kong, Pokfulam Road (Hong Kong); Hui, C. Y. [Department of Astronomy and Space Science, Chungnam National University, Daejeon (Korea, Republic of); Kong, A. K. H.; Tam, P. H. T. [Institute of Astronomy and Department of Physics, National Tsing Hua University, Hsinchu, Taiwan (China); Dogiel, V. A., E-mail: cyhui@cnu.ac.kr [I. E. Tamm Theoretical Physics Division of P. N. Lebedev Institute of Physics, Leninskii pr. 53, 119991 Moscow (Russian Federation)

2014-06-20

In re-analyzing the archival Chandra data of the globular cluster 47 Tucanae, we have detected a new diffuse X-ray emission feature within the half-mass radius of the cluster. The spectrum of the diffuse emission can be described by a power-law model plus a plasma component with photon index Γ ∼ 1.0 and plasma temperature kT ∼ 0.2 keV. While the thermal component is apparently uniform, the non-thermal contribution falls off exponentially from the core. The observed properties could possibly be explained in the context of multiple shocks resulting from the collisions among the stellar wind in the cluster and the inverse Compton scattering between the pulsar wind and the relic photons.

MS-SQL data base programming

Energy Technology Data Exchange (ETDEWEB)

Noh, Chang Bae; Kim, Nam Jung; Lee, Hyeong Gyo

2002-07-15

This is about MS-SQL data base programming which is divided into thirteen chapters. The contents of this book are to understand MS-SQL 2000 DBMS with its composition, new function and history of MS-SQL, to learn conception of data base, install, run and closing of MS-SQL 2000 DBMS, to deal with the basic of MS-SQL DBMS, to handle the intermediate level of MS-SQL DBMS, to deal with MS-SQL DBMS in advanced level, to practice query like changing data base and checking of data lists, function on its use and data diff, get date, date add, char, upper and system function, set-up of MS-SQL ODBC, constructing of web server of windows 2000, web programming using visual studio.net.making board and making reference room.

MS-SQL data base programming

International Nuclear Information System (INIS)

Noh, Chang Bae; Kim, Nam Jung; Lee, Hyeong Gyo

2002-07-01

This is about MS-SQL data base programming which is divided into thirteen chapters. The contents of this book are to understand MS-SQL 2000 DBMS with its composition, new function and history of MS-SQL, to learn conception of data base, install, run and closing of MS-SQL 2000 DBMS, to deal with the basic of MS-SQL DBMS, to handle the intermediate level of MS-SQL DBMS, to deal with MS-SQL DBMS in advanced level, to practice query like changing data base and checking of data lists, function on its use and data diff, get date, date add, char, upper and system function, set-up of MS-SQL ODBC, constructing of web server of windows 2000, web programming using visual studio.net.making board and making reference room.

Analytical Method Details (MS): SE2_MS3 [Metabolonote[Archive

Lifescience Database Archive (English)

Full Text Available 00.0-1500.0); 2: ITMS + c norm !corona !pi Dep MS/MS Most intense ion from (1)., Rejected mass=284.2000;300.2000;328.2000;344.2000;372.2000;388.2000;416.3000;432.3000;460.0000. ...

110 1*Atkuru Veera Venkata Naga Krishna Sunil Kumar, 2Chandra ...

African Journals Online (AJOL)

of VDL in biological fluids. These include HPLC with amperometry detection [3], HPLC with UV detection [4], HPLC with fluorescence detection. [5], LC-MS [6,7], GC-MS [8,9] and square-wave adsorption ... stability indicating liquid chromatography with. UV detection ... in drug analysis and the spectrophotometric methods ...

Relapsing-Remitting MS (RRMS)

Medline Plus

Full Text Available ... Treating MS d Comprehensive Care Developing a Healthcare Team Make the Most of Your Doctor Visits Advance Medical Directives d Find an MS Care Provider Partners in MS Care d Managing Relapses Plasmapheresis d Rehabilitation Functional Electrical Stimulation (FES) ...

MS Based Metabonomics

Energy Technology Data Exchange (ETDEWEB)

Want, Elizabeth J.; Metz, Thomas O.

2010-03-01

Metabonomics is the latest and least mature of the systems biology triad, which also includes genomics and proteomics, and has its origins in the early orthomolecular medicine work pioneered by Linus Pauling and Arthur Robinson. It was defined by Nicholson and colleagues in 1999 as the quantitative measurement of perturbations in the metabolite complement of an integrated biological system in response to internal or external stimuli, and is often used today to describe many non-global types of metabolite analyses. Applications of metabonomics are extensive and include toxicology, nutrition, pharmaceutical research and development, physiological monitoring and disease diagnosis. For example, blood samples from millions of neonates are tested routinely by mass spectrometry (MS) as a diagnostic tool for inborn errors of metabolism. The metabonome encompasses a wide range of structurally diverse metabolites; therefore, no single analytical platform will be sufficient. Specialized sample preparation and detection techniques are required, and advances in NMR and MS technologies have led to enhanced metabonome coverage, which in turn demands improved data analysis approaches. The role of MS in metabonomics is still evolving as instrumentation and software becomes more sophisticated and as researchers realize the strengths and limitations of current technology. MS offers a wide dynamic range, high sensitivity, and reproducible, quantitative analysis. These attributes are essential for addressing the challenges of metabonomics, as the range of metabolite concentrations easily exceeds nine orders of magnitude in biofluids, and the diversity of molecular species ranges from simple amino and organic acids to lipids and complex carbohydrates. Additional challenges arise in generating a comprehensive metabolite profile, downstream data processing and analysis, and structural characterization of important metabolites. A typical workflow of MS-based metabonomics is shown in Figure

A Joint Chandra and Swift View of the 2015 X-ray Dust-scattering Echo of V404 Cygni

Science.gov (United States)

Heinz, S.; Corrales, L.; Smith, R.; Brandt, W. N.; Jonker, P. G.; Plotkin, R. M.; Neilsen, J.

2016-07-01

We present a combined analysis of the Chandra and Swift observations of the 2015 X-ray echo of V404 Cygni. Using a stacking analysis, we identify eight separate rings in the echo. We reconstruct the soft X-ray light curve of the 2015 June outburst using the high-resolution Chandra images and cross-correlations of the radial intensity profiles, indicating that about 70% of the outburst fluence occurred during the bright flare at the end of the outburst on MJD 57199.8. By deconvolving the intensity profiles with the reconstructed outburst light curve, we show that the rings correspond to eight separate dust concentrations with precise distance determinations. We further show that the column density of the clouds varies significantly across the field of view, with the centroid of most of the clouds shifted toward the Galactic plane, relative to the position of V404 Cyg, invalidating the assumption of uniform cloud column typically made in attempts to constrain dust properties from light echoes. We present a new XSPEC spectral dust-scattering model that calculates the differential dust-scattering cross section for a range of commonly used dust distributions and compositions and use it to jointly fit the entire set of Swift echo data. We find that a standard Mathis-Rumpl-Nordsieck model provides an adequate fit to the ensemble of echo data. The fit is improved by allowing steeper dust distributions, and models with simple silicate and graphite grains are preferred over models with more complex composition.

LC-MS-MS identification of drug metabolites obtained by metalloporphyrin mediated oxidation

Directory of Open Access Journals (Sweden)

Maurin Andrea J. M.

2003-01-01

Full Text Available In this paper we report the application of liquid chromatography-mass spectrometry (LC-MS-MS to the identification of the products formed by oxidation of albendazole and disopyramide with metalloporphyrins in dichloroethane, using iodosylbenzene as an oxygen donor. Our results show that LC-MS-MS is a powerful tool to study the in vitro metabolism of drugs, allowing the identification of known and unknown metabolites. In addition, it was observed that the catalyst system used resulted in the formation of the same metabolites as obtained in vivo, although for disopyramide other products were also observed.

DBS-LC-MS/MS assay for caffeine: validation and neonatal application.

Science.gov (United States)

Bruschettini, Matteo; Barco, Sebastiano; Romantsik, Olga; Risso, Francesco; Gennai, Iulian; Chinea, Benito; Ramenghi, Luca A; Tripodi, Gino; Cangemi, Giuliana

2016-09-01

DBS might be an appropriate microsampling technique for therapeutic drug monitoring of caffeine in infants. Nevertheless, its application presents several issues that still limit its use. This paper describes a validated DBS-LC-MS/MS method for caffeine. The results of the method validation showed an hematocrit dependence. In the analysis of 96 paired plasma and DBS clinical samples, caffeine levels measured in DBS were statistically significantly lower than in plasma but the observed differences were independent from hematocrit. These results clearly showed the need for extensive validation with real-life samples for DBS-based methods. DBS-LC-MS/MS can be considered to be a good alternative to traditional methods for therapeutic drug monitoring or PK studies in preterm infants.

Observations of the Crab Nebula with the Chandra X-Ray Observatory During the Gamma-Ray Flare of 2011 April

Science.gov (United States)

Weisskopf, Martin C.

2012-01-01

Recently, using the AGILE and Fermi satellites, gamma-ray flares have been discovered from the direction of the Crab Nebula (Tavani et al. 2011, Abdo et al. 2011). We have been using the Chandra X-Ray observatory to monitor the Crab on a monthly cadence since just after the 2010 September gamma-ray flare. We were fortunate to trigger series of pre-planned target of opportunity observations during the 2011 April flare. We present the results of these observations and address some implications both for now and for the future.

Monitoring Chandra Observations of the Quasi-persistent Neutron Star X-Ray Transient MXB 1659-29 in Quiescence: The Cooling Curve of the Heated Neutron Star Crust

NARCIS (Netherlands)

Wijnands, R.A.D.; Homan, J.; Miller, J.M.; Lewin, W.H.G.

2004-01-01

We have observed the quasi-persistent neutron star X-ray transient and eclipsing binary MXB 1659-29 in quiescence on three occasions with Chandra. The purpose of our observations was to monitor the quiescent behavior of the source after its last prolonged (~2.5 yr) outburst that ended in 2001

LATE-TIME EVOLUTION OF COMPOSITE SUPERNOVA REMNANTS: DEEP CHANDRA OBSERVATIONS AND HYDRODYNAMICAL MODELING OF A CRUSHED PULSAR WIND NEBULA IN SNR G327.1-1.1

Energy Technology Data Exchange (ETDEWEB)

Temim, Tea [Observational Cosmology Lab, Code 665, NASA Goddard Space Flight Center, Greenbelt, MD 20771 (United States); Slane, Patrick [Harvard-Smithsonian Center for Astrophysics, 60 Garden Street, Cambridge, MA 02138 (United States); Kolb, Christopher; Blondin, John [North Carolina State University, 421 Riddick Hall, Raleigh, NC 27695 (United States); Hughes, John P. [Rutgers University, 57 US Highway 1, New Brunswick, NJ 08901 (United States); Bucciantini, Niccoló [INAF Osservatorio Astrofisico di Arcetri, Largo Enrico Fermi, 5, 50125, Firenze Italy (Italy)

2015-07-20

In an effort to better understand the evolution of composite supernova remnants (SNRs) and the eventual fate of relativistic particles injected by their pulsars, we present a multifaceted investigation of the interaction between a pulsar wind nebula (PWN) and its host SNR G327.1-1.1. Our 350 Chandra X-ray observations of SNR G327.1-1.1 reveal a highly complex morphology: a cometary structure resembling a bow shock, prong-like features extending into large arcs in the SNR interior, and thermal emission from the SNR shell. Spectral analysis of the non-thermal emission offers clues about the origin of the PWN structures, while enhanced abundances in the PWN region provide evidence for a mixing of supernova ejecta with PWN material. The overall morphology and spectral properties of the SNR suggest that the PWN has undergone an asymmetric interaction with the SNR reverse shock (RS), whichcan occur as a result of a density gradient in the ambient medium and/or a moving pulsar that displaces the PWN from the center of the remnant. We present hydrodynamical simulations of G327.1-1.1 that show that its morphology and evolution can be described by a ∼17,000-year-old composite SNR that expanded into a density gradient with an orientation perpendicular to the pulsar’s motion. We also show that the RS/PWN interaction scenario can reproduce the broadband spectrum of the PWN from radio to γ-ray wavelengths. The analysis and modeling presented in this work have important implications for our general understanding of the structure and evolution of composite SNRs.

Late-Time Evolution of Composite Supernova Remnants: Deep Chandra Observations and Hydrodynamical Modeling of a Crushed Pulsar Wind Nebula in SNR G327.1-1.1

Science.gov (United States)

Temim, Tea; Slane, Patrick; Kolb, Christopher; Blondin, John; Hughes, John P.; Bucciantini, Niccolo

2015-01-01

In an effort to better understand the evolution of composite supernova remnants (SNRs) and the eventual fate of relativistic particles injected by their pulsars, we present a multifaceted investigation of the interaction between a pulsar wind nebula (PWN) and its host SNR G327.1-1.1. Our 350 ks Chandra X-ray observations of SNR G327.1-1.1 reveal a highly complex morphology; a cometary structure resembling a bow shock, prong-like features extending into large arcs in the SNR interior, and thermal emission from the SNR shell. Spectral analysis of the non-thermal emission offers clues about the origin of the PWN structures, while enhanced abundances in the PWN region provide evidence for mixing of supernova ejecta with PWN material. The overall morphology and spectral properties of the SNR suggest that the PWN has undergone an asymmetric interaction with the SNR reverse shock(RS) that can occur as a result of a density gradient in the ambient medium and or a moving pulsar that displaces the PWN from the center of the remnant. We present hydrodynamical simulations of G327.1-1.1 that show that its morphology and evolution can be described by a approx. 17,000 yr old composite SNR that expanded into a density gradient with an orientation perpendicular to the pulsar's motion. We also show that the RSPWN interaction scenario can reproduce the broadband spectrum of the PWN from radio to gamma-ray wavelengths. The analysis and modeling presented in this work have important implications for our general understanding of the structure and evolution of composite SNRs.

A federated information management system for the Deep Space Network. M.S. Thesis - Univ. of Southern California

Science.gov (United States)

Dobinson, E.

1982-01-01

General requirements for an information management system for the deep space network (DSN) are examined. A concise review of available database management system technology is presented. It is recommended that a federation of logically decentralized databases be implemented for the Network Information Management System of the DSN. Overall characteristics of the federation are specified, as well as reasons for adopting this approach.

MsLDR-creator: a web service to design msLDR assays.

Science.gov (United States)

Bormann, Felix; Dahl, Andreas; Sers, Christine

2012-03-01

MsLDR-creator is a free web service to design assays for the new DNA methylation detection method msLDR. The service provides the user with all necessary information about the oligonucleotides required for the measurement of a given CpG within a sequence of interest. The parameters are calculated by the nearest neighbour approach to achieve optimal behaviour during the experimental procedure. In addition, to guarantee a good start using msLDR, further information, like protocols and hints and tricks, are provided.

Why & When Deep Learning Works: Looking Inside Deep Learnings

OpenAIRE

Ronen, Ronny

2017-01-01

The Intel Collaborative Research Institute for Computational Intelligence (ICRI-CI) has been heavily supporting Machine Learning and Deep Learning research from its foundation in 2012. We have asked six leading ICRI-CI Deep Learning researchers to address the challenge of "Why & When Deep Learning works", with the goal of looking inside Deep Learning, providing insights on how deep networks function, and uncovering key observations on their expressiveness, limitations, and potential. The outp...

Analytical Method Details (MS): SE29_MS1 [Metabolonote[Archive

Lifescience Database Archive (English)

Full Text Available SE29_MS1 LC-FT-ICR-MS ESI positive method 1 Agilent1100 HPLC (Agilent), LTQ-FT (The... (100mg) are solved in 300uL 80% methanol solution. 20uL sample is injected into HPLC after 0.2um membrane filter treatment. HPLC

Chandra and XMM-Newton observations of the low-luminosity X-ray pulsators SAX J1324.4−6200 and SAX J1452.8−5949

NARCIS (Netherlands)

Kaur, R.; Wijnands, R.; Patruno, A.; Testa, V.; Israel, G.; Degenaar, N.; Paul, B.; Kumar, B.

2009-01-01

We present results from our Chandra and XMM-Newton observations of two low-luminosity X-ray pulsators SAX J1324.4-6200 and SAX J1452.8-5949 which have spin periods of 172 and 437 s, respectively. The XMM-Newton spectra for both sources can be fitted well with a simple power-law model of photon

Cometary X-ray Emission: the View After the First Chandra Observations

Science.gov (United States)

Lisse, C. M.

2002-01-01

The unexpected discovery of x-ray emission from Comet Hyakutake in March 1996 (Lisse et al. 1996) has produced a number of questions about the physical mechanism producing the radiation. The original detection and subsequent observations (Dennerl et al. 1997, Mumma et al. 1997, Krasnopolsky et al. 1998, Owens et al. 1998, Lisse et al. 1999) have shown that the very soft (best fit thermal bremsstrahlung model kT ~ 0.2 keV) emission is due to an interaction between the solar wind and the comet's atmosphere. Using the results from the 15 comets detected to date in x-rays, we report on the latest results on cometary x-ray emission, including new results from Chandra and XMM. As-observed morphologies, spectra, and light curves will be discussed. Our emphasis will be on understanding the physical mechanism producing the emission, and using this to determine the nature of the cometary coma, the structure of the solar wind in the heliosphere, and the source of the local soft x-ray background. This work has been graciously supported by grants from the NASA Planetary Astronomy and Astrophysical Data Programs.

Running of the charm-quark mass from HERA deep-inelastic scattering data

International Nuclear Information System (INIS)

Gizhko, A.; Geiser, A.; Moch, S.

2017-04-01

Combined HERA data on charm production in deep-inelastic scattering have previously been used to determine the charm-quark running mass m_c(m_c) in the MS renormalisation scheme. Here, the same data are used as a function of the photon virtuality Q"2 to evaluate the charm-quark running mass at different scales to one-loop order, in the context of a next-to-leading order QCD analysis. The scale dependence of the mass is found to be consistent with QCD expectations.

A comparison between DART-MS and DSA-MS in the forensic analysis of writing inks.

Science.gov (United States)

Drury, Nicholas; Ramotowski, Robert; Moini, Mehdi

2018-05-23

Ambient ionization mass spectrometry is gaining momentum in forensic science laboratories because of its high speed of analysis, minimal sample preparation, and information-rich results. One such application of ambient ionization methodology includes the analysis of writing inks from questioned documents where colorants of interest may not be soluble in common solvents, rendering thin layer chromatography (TLC) and separation-mass spectrometry methods such as LC/MS (-MS) impractical. Ambient ionization mass spectrometry uses a variety of ionization techniques such as penning ionization in Direct Analysis in Real Time (DART), and atmospheric pressure chemical ionization in Direct Sample Analysis (DSA), and electrospray ionization in Desorption Electrospray Ionization (DESI). In this manuscript, two of the commonly used ambient ionization techniques are compared: Perkin Elmer DSA-MS and IonSense DART in conjunction with a JEOL AccuTOF MS. Both technologies were equally successful in analyzing writing inks and produced similar spectra. DSA-MS produced less background signal likely because of its closed source configuration; however, the open source configuration of DART-MS provided more flexibility for sample positioning for optimum sensitivity and thereby allowing smaller piece of paper containing writing ink to be analyzed. Under these conditions, the minimum sample required for DART-MS was 1mm strokes of ink on paper, whereas DSA-MS required a minimum of 3mm. Moreover, both techniques showed comparable repeatability. Evaluation of the analytical figures of merit, including sensitivity, linear dynamic range, and repeatability, for DSA-MS and DART-MS analysis is provided. To the forensic context of the technique, DART-MS was applied to the analysis of United States Secret Service ink samples directly on a sampling mesh, and the results were compared with DSA-MS of the same inks on paper. Unlike analysis using separation mass spectrometry, which requires sample

Natural isotope correction of MS/MS measurements for metabolomics and (13)C fluxomics.

Science.gov (United States)

Niedenführ, Sebastian; ten Pierick, Angela; van Dam, Patricia T N; Suarez-Mendez, Camilo A; Nöh, Katharina; Wahl, S Aljoscha

2016-05-01

Fluxomics and metabolomics are crucial tools for metabolic engineering and biomedical analysis to determine the in vivo cellular state. Especially, the application of (13)C isotopes allows comprehensive insights into the functional operation of cellular metabolism. Compared to single MS, tandem mass spectrometry (MS/MS) provides more detailed and accurate measurements of the metabolite enrichment patterns (tandem mass isotopomers), increasing the accuracy of metabolite concentration measurements and metabolic flux estimation. MS-type data from isotope labeling experiments is biased by naturally occurring stable isotopes (C, H, N, O, etc.). In particular, GC-MS(/MS) requires derivatization for the usually non-volatile intracellular metabolites introducing additional natural isotopes leading to measurements that do not directly represent the carbon labeling distribution. To make full use of LC- and GC-MS/MS mass isotopomer measurements, the influence of natural isotopes has to be eliminated (corrected). Our correction approach is analyzed for the two most common applications; (13)C fluxomics and isotope dilution mass spectrometry (IDMS) based metabolomics. Natural isotopes can have an impact on the calculated flux distribution which strongly depends on the substrate labeling and the actual flux distribution. Second, we show that in IDMS based metabolomics natural isotopes lead to underestimated concentrations that can and should be corrected with a nonlinear calibration. Our simulations indicate that the correction for natural abundance in isotope based fluxomics and quantitative metabolomics is essential for correct data interpretation. © 2015 Wiley Periodicals, Inc.

Biogeography of Persephonella in deep-sea hydrothermal vents of the Western Pacific.

Directory of Open Access Journals (Sweden)

Sayaka eMino

2013-04-01

Full Text Available Deep-sea hydrothermal vent fields are areas on the seafloor with high biological productivity fueled by microbial chemosynthesis. Members of the Aquificales genus Persephonella are obligately chemosynthetic bacteria, and appear to be key players in carbon, sulfur, and nitrogen cycles in high temperature habitats at deep-sea vents. Although this group of bacteria has cosmopolitan distribution in deep-sea hydrothermal ecosystem around the world, little is known about their population structure such as intraspecific genomic diversity, distribution pattern, and phenotypic diversity. We developed the multi-locus sequence analysis (MLSA scheme for their genomic characterization. Sequence variation was determined in five housekeeping genes and one functional gene of 36 P. hydrogeniphila strains originated from the Okinawa Trough and the South Mariana Trough. Although the strains share > 98.7% similarities in 16S rRNA gene sequences, MLSA revealed 35 different sequence types, indicating their extensive genomic diversity. A phylogenetic tree inferred from all concatenated gene sequences revealed the clustering of isolates according to the geographic origin. In addition, the phenotypic clustering pattern inferred from whole-cell matrix-assisted laser desorption ionization-time of flight mass spectrometry (MALDI-TOF/MS analysis can be correlated to their MLSA clustering pattern. This study represents the first MLSA combined with phenotypic analysis indicative of allopatric speciation of deep-sea hydrothermal vent bacteria.

Chandra's Ultimate Angular Resolution: Studies of the HRC-I Point Spread Function

Science.gov (United States)

Juda, Michael; Karovska, M.

2010-03-01

The Chandra High Resolution Camera (HRC) should provide an ideal imaging match to the High-Resolution Mirror Assembly (HRMA). The laboratory-measured intrinsic resolution of the HRC is 20 microns FWHM. HRC event positions are determined via a centroiding method rather than by using discrete pixels. This event position reconstruction method and any non-ideal performance of the detector electronics can introduce distortions in event locations that, when combined with spacecraft dither, produce artifacts in source images. We compare ray-traces of the HRMA response to "on-axis" observations of AR Lac and Capella as they move through their dither patterns to images produced from filtered event lists to characterize the effective intrinsic PSF of the HRC-I. A two-dimensional Gaussian, which is often used to represent the detector response, is NOT a good representation of the intrinsic PSF of the HRC-I; the actual PSF has a sharper peak and additional structure which will be discussed. This work was supported under NASA contract NAS8-03060.

Development and Validation of an LC-MS/MS Method and Comparison with a GC-MS Method to Measure Phenytoin in Human Brain Dialysate, Blood, and Saliva

Directory of Open Access Journals (Sweden)

Raphael Hösli

2018-01-01

Full Text Available Phenytoin (PHT is one of the most often used critical dose drugs, where insufficient or excessive dosing can have severe consequences such as seizures or toxicity. Thus, the monitoring and precise measuring of PHT concentrations in patients is crucial. This study develops and validates an LC-MS/MS method for the measurement of phenytoin concentrations in different body compartments (i.e., human brain dialysate, blood, and saliva and compares it with a formerly developed GC-MS method that measures PHT in the same biological matrices. The two methods are evaluated and compared based on their analytical performance, appropriateness to analyze human biological samples, including corresponding extraction and cleanup procedures, and their validation according to ISO 17025/FDA Guidance for Industry. The LC-MS/MS method showed a higher performance compared with the GC-MS method. The LC-MS/MS was more sensitive, needed a smaller sample volume (25 µL and less chemicals, was less time consuming (cleaning up, sample preparation, and analysis, and resulted in a better LOD ( 0.995 for all tested matrices (blood, saliva, and dialysate. For larger sample numbers as in pharmacokinetic/pharmacodynamic studies and for bedside as well as routine analyses, the LC-MS/MS method offers significant advantages over the GC-MS method.

Structure Annotation and Quantification of Wheat Seed Oxidized Lipids by High-Resolution LC-MS/MS.

Science.gov (United States)

Riewe, David; Wiebach, Janine; Altmann, Thomas

2017-10-01

Lipid oxidation is a process ubiquitous in life, but the direct and comprehensive analysis of oxidized lipids has been limited by available analytical methods. We applied high-resolution liquid chromatography-mass spectrometry (LC-MS) and tandem mass spectrometry (MS/MS) to quantify oxidized lipids (glycerides, fatty acids, phospholipids, lysophospholipids, and galactolipids) and implemented a platform-independent high-throughput-amenable analysis pipeline for the high-confidence annotation and acyl composition analysis of oxidized lipids. Lipid contents of 90 different naturally aged wheat ( Triticum aestivum ) seed stocks were quantified in an untargeted high-resolution LC-MS experiment, resulting in 18,556 quantitative mass-to-charge ratio features. In a posthoc liquid chromatography-tandem mass spectrometry experiment, high-resolution MS/MS spectra (5 mD accuracy) were recorded for 8,957 out of 12,080 putatively monoisotopic features of the LC-MS data set. A total of 353 nonoxidized and 559 oxidized lipids with up to four additional oxygen atoms were annotated based on the accurate mass recordings (1.5 ppm tolerance) of the LC-MS data set and filtering procedures. MS/MS spectra available for 828 of these annotations were analyzed by translating experimentally known fragmentation rules of lipids into the fragmentation of oxidized lipids. This led to the identification of 259 nonoxidized and 365 oxidized lipids by both accurate mass and MS/MS spectra and to the determination of acyl compositions for 221 nonoxidized and 295 oxidized lipids. Analysis of 15-year aged wheat seeds revealed increased lipid oxidation and hydrolysis in seeds stored in ambient versus cold conditions. © 2017 The author(s). All Rights Reserved.

Relapsing-Remitting MS (RRMS)

Medline Plus

Full Text Available ... and problems with cognition (learning and memory or information processing). People with progressive forms of MS are more likely to experience gradually worsening problems with walking and mobility, along with whatever other symptoms they may have. Diagnosing ... MS Society is Here to Help Need More Information? We Are Here Our MS Navigators help identify ...

A SEARCH FOR LYMAN BREAK GALAXIES IN THE CHANDRA DEEP FIELD SOUTH USING SWIFT ULTRAVIOLET/OPTICAL TELESCOPE

International Nuclear Information System (INIS)

Basu-Zych, Antara R.; Hornschemeier, Ann E.; Hoversten, Erik A.; Gronwall, Caryl; Lehmer, Bret

2011-01-01

While the Swift satellite is primarily designed to study gamma-ray bursts, its ultraviolet and optical imaging and spectroscopy capabilities are also being used for a variety of scientific programs. In this study, we use the UV/Optical Telescope (UVOT) instrument on board Swift to discover 0.5 2 at >60 ks exposure time, achieving a limiting magnitude of u * /M sun ) = 9.4 ± 0.6, which is slightly lower than z ∼ 3 LBGs ((logM * /Ms un ) = 10.2 ± 0.4) and slightly higher compared with the z ∼ 1 CDF-S galaxies ((logM * /M sun ) = 8.7 ± 0.7). Similarly, our sample of z ∼ 1 LBGs has SFRs (derived using both ultraviolet and infrared data, where available) of (logSFR/(M sun yr -1 )) = 0.7 ± 0.6, nearly an order of magnitude lower than z ∼ 3 LBGs ((logSFR/M sun yr -1 ) = 1.5 ± 0.4), but slightly higher than the comparison z ∼ 1 sample of CDF-S galaxies ((logSFR/M sun yr -1 ) = 0.2 ± 0.7). We find that our z ∼ 1 UV-dropouts have (A FUV ) = 2.0 ± 1.0, which is higher than z ∼ 3 LBGs ((A FUV ) = 1.0 ± 0.5), but similar to the distribution of dust attenuations in the other CDF-S galaxies ((A FUV ) ∼ 2.8 ± 1.5). Using the GOODS-South multiwavelength catalog of galaxies, we simulate a larger and fainter sample of LBGs to compare their properties with those of the UVOT-selected LBG sample. We conclude that UVOT can be useful for finding and studying the bright end of 0.5 < z < 2.0 LBGs.

Assessment of deep tissue hyperalgesia in the groin – a method comparison of electrical vs. pressure stimulation

DEFF Research Database (Denmark)

Aasvang, E K; Werner, M U; Kehlet, H

2014-01-01

BACKGROUND: Deep pain complaints are more frequent than cutaneous in post-surgical patients, and a prevalent finding in quantitative sensory testing studies. However, the preferred assessment method - pressure algometry - is indirect and tissue unspecific, hindering advances in treatment and prev......BACKGROUND: Deep pain complaints are more frequent than cutaneous in post-surgical patients, and a prevalent finding in quantitative sensory testing studies. However, the preferred assessment method - pressure algometry - is indirect and tissue unspecific, hindering advances in treatment...... thresholds to pressure algometry, by performing identical test-retest sequences 10 days apart, in deep tissues in the groin region. Electrical stimulation was performed by five up-and-down staircase series of single impulses of 0.04 ms duration, starting from 0 mA in increments of 0.2 mA until a threshold......: The presented tissue-specific direct deep tissue electrical stimulation technique has equal or superior reliability compared with the indirect tissue-unspecific stimulation by pressure algometry. This method may facilitate advances in mechanism based preventive and treatment strategies in acute and chronic post...

EKG-based detection of deep brain stimulation in fMRI studies.

Science.gov (United States)

Fiveland, Eric; Madhavan, Radhika; Prusik, Julia; Linton, Renee; Dimarzio, Marisa; Ashe, Jeffrey; Pilitsis, Julie; Hancu, Ileana

2018-04-01

To assess the impact of synchronization errors between the assumed functional MRI paradigm timing and the deep brain stimulation (DBS) on/off cycling using a custom electrocardiogram-based triggering system METHODS: A detector for measuring and predicting the on/off state of cycling deep brain stimulation was developed and tested in six patients in office visits. Three-electrode electrocardiogram measurements, amplified by a commercial bio-amplifier, were used as input for a custom electronics box (e-box). The e-box transformed the deep brain stimulation waveforms into transistor-transistor logic pulses, recorded their timing, and propagated it in time. The e-box was used to trigger task-based deep brain stimulation functional MRI scans in 5 additional subjects; the impact of timing accuracy on t-test values was investigated in a simulation study using the functional MRI data. Following locking to each patient's individual waveform, the e-box was shown to predict stimulation onset with an average absolute error of 112 ± 148 ms, 30 min after disconnecting from the patients. The subsecond accuracy of the e-box in predicting timing onset is more than adequate for our slow varying, 30-/30-s on/off stimulation paradigm. Conversely, the experimental deep brain stimulation onset prediction accuracy in the absence of the e-box, which could be off by as much as 4 to 6 s, could significantly decrease activation strength. Using this detector, stimulation can be accurately synchronized to functional MRI acquisitions, without adding any additional hardware in the MRI environment. Magn Reson Med 79:2432-2439, 2018. © 2017 International Society for Magnetic Resonance in Medicine. © 2017 International Society for Magnetic Resonance in Medicine.

Breaking through the uncertainty ceiling in LA-ICP-MS U-Pb geochronology

Science.gov (United States)

Horstwood, M.

2016-12-01

Sources of systematic uncertainty associated with session-to-session bias are the dominant contributor to the 2% (2s) uncertainty ceiling that currently limits the accuracy of LA-ICP-MS U-Pb geochronology. Sources include differential downhole fractionation (LIEF), `matrix effects' and ablation volume differences, which result in irreproducibility of the same reference material across sessions. Current mitigation methods include correcting for LIEF mathematically, using matrix-matched reference materials, annealing material to reduce or eliminate radiation damage effects and tuning for robust plasma conditions. Reducing the depth and volume of ablation can also mitigate these problems and should contribute to the reduction of the uncertainty ceiling. Reducing analysed volume leads to increased detection efficiency, reduced matrix-effects, eliminates LIEF, obviates ablation rate differences and reduces the likelihood of intercepting complex growth zones with depth, thereby apparently improving material homogeneity. High detection efficiencies (% level) and low sampling volumes (20um box, 1-2um deep) can now be achieved using MC-ICP-MS such that low volume ablations should be considered part of the toolbox of methods targeted at improving the reproducibility of LA-ICP-MS U-Pb geochronology. In combination with other strategies these improvements should be feasible on any ICP platform. However, reducing the volume of analysis reduces detected counts and requires a change of analytical approach in order to mitigate this. Appropriate strategies may include the use of high efficiency cell and torch technologies and the optimisation of acquisition protocols and data handling techniques such as condensing signal peaks, using log ratios and total signal integration. The tools required to break the 2% (2s) uncertainty ceiling in LA-ICP-MS U-Pb geochronology are likely now known but require a coherent strategy and change of approach to combine their implementation and realise

MR fingerprinting Deep RecOnstruction NEtwork (DRONE).

Science.gov (United States)

Cohen, Ouri; Zhu, Bo; Rosen, Matthew S

2018-09-01

Demonstrate a novel fast method for reconstruction of multi-dimensional MR fingerprinting (MRF) data using deep learning methods. A neural network (NN) is defined using the TensorFlow framework and trained on simulated MRF data computed with the extended phase graph formalism. The NN reconstruction accuracy for noiseless and noisy data is compared to conventional MRF template matching as a function of training data size and is quantified in simulated numerical brain phantom data and International Society for Magnetic Resonance in Medicine/National Institute of Standards and Technology phantom data measured on 1.5T and 3T scanners with an optimized MRF EPI and MRF fast imaging with steady state precession (FISP) sequences with spiral readout. The utility of the method is demonstrated in a healthy subject in vivo at 1.5T. Network training required 10 to 74 minutes; once trained, data reconstruction required approximately 10 ms for the MRF EPI and 76 ms for the MRF FISP sequence. Reconstruction of simulated, noiseless brain data using the NN resulted in a RMS error (RMSE) of 2.6 ms for T 1 and 1.9 ms for T 2 . The reconstruction error in the presence of noise was less than 10% for both T 1 and T 2 for SNR greater than 25 dB. Phantom measurements yielded good agreement (R 2  = 0.99/0.99 for MRF EPI T 1 /T 2 and 0.94/0.98 for MRF FISP T 1 /T 2 ) between the T 1 and T 2 estimated by the NN and reference values from the International Society for Magnetic Resonance in Medicine/National Institute of Standards and Technology phantom. Reconstruction of MRF data with a NN is accurate, 300- to 5000-fold faster, and more robust to noise and dictionary undersampling than conventional MRF dictionary-matching. © 2018 International Society for Magnetic Resonance in Medicine.

Determination of drug residues by CLAR-MS/MS in animal tissues

International Nuclear Information System (INIS)

Brenes Jimenez, Jose Eduardo

2009-01-01

Produced food of animal origin, present the possibility of occurrence of any contact with substances that have negative effects on the health of people who consume them. The use of drugs in veterinary medicine is one of the possible sources of such waste; so, the conditions for the analysis of some classes of antibiotics in animal tissues are based on the study. Costa Rica and the countries that are export destination, have regulation and programs for control before to be distributed in local markets, or post if it is received any complaint of pollution. The high resolution liquid chromatography coupled to mass spectrometers (CLAR-MS/MS) allows the analysis of analytes monitored, according to the specifications required by the legislation. The cases of two laboratories in Costa Rica are presented as the only ones who have the ability to perform the analysis of drug residues CLAR-MS/MS. (author) [es

The Ultra-fast Outflow of the Quasar PG 1211+143 as Viewed by Time-averaged Chandra Grating Spectroscopy

Science.gov (United States)

Danehkar, Ashkbiz; Nowak, Michael A.; Lee, Julia C.; Kriss, Gerard A.; Young, Andrew J.; Hardcastle, Martin J.; Chakravorty, Susmita; Fang, Taotao; Neilsen, Joseph; Rahoui, Farid; Smith, Randall K.

2018-02-01

We present a detailed X-ray spectral study of the quasar PG 1211+143 based on Chandra High Energy Transmission Grating Spectrometer (HETGS) observations collected in a multi-wavelength campaign with UV data using the Hubble Space Telescope Cosmic Origins Spectrograph (HST-COS) and radio bands using the Jansky Very Large Array (VLA). We constructed a multi-wavelength ionizing spectral energy distribution using these observations and archival infrared data to create XSTAR photoionization models specific to the PG 1211+143 flux behavior during the epoch of our observations. Our analysis of the Chandra-HETGS spectra yields complex absorption lines from H-like and He-like ions of Ne, Mg, and Si, which confirm the presence of an ultra-fast outflow (UFO) with a velocity of approximately ‑17,300 km s‑1 (outflow redshift z out ∼ ‑0.0561) in the rest frame of PG 1211+143. This absorber is well described by an ionization parameter {log}ξ ∼ 2.9 {erg} {{{s}}}-1 {cm} and column density {log}{N}{{H}}∼ 21.5 {{cm}}-2. This corresponds to a stable region of the absorber’s thermal stability curve, and furthermore its implied neutral hydrogen column is broadly consistent with a broad Lyα absorption line at a mean outflow velocity of approximately ‑16,980 km s‑1 detected by our HST-COS observations. Our findings represent the first simultaneous detection of a UFO in both X-ray and UV observations. Our VLA observations provide evidence for an active jet in PG 1211+143, which may be connected to the X-ray and UV outflows; this possibility can be evaluated using very-long-baseline interferometric observations.

msBP: An R Package to Perform Bayesian Nonparametric Inference Using Multiscale Bernstein Polynomials Mixtures

Directory of Open Access Journals (Sweden)

Antonio Canale

2017-06-01

Full Text Available msBP is an R package that implements a new method to perform Bayesian multiscale nonparametric inference introduced by Canale and Dunson (2016. The method, based on mixtures of multiscale beta dictionary densities, overcomes the drawbacks of Pólya trees and inherits many of the advantages of Dirichlet process mixture models. The key idea is that an infinitely-deep binary tree is introduced, with a beta dictionary density assigned to each node of the tree. Using a multiscale stick-breaking characterization, stochastically decreasing weights are assigned to each node. The result is an infinite mixture model. The package msBP implements a series of basic functions to deal with this family of priors such as random densities and numbers generation, creation and manipulation of binary tree objects, and generic functions to plot and print the results. In addition, it implements the Gibbs samplers for posterior computation to perform multiscale density estimation and multiscale testing of group differences described in Canale and Dunson (2016.

Late-onset progressive visual loss in a man with unusual MRI findings: MS, Harding's, Leber's or Leber's Plus?

LENUS (Irish Health Repository)

Cawley, N

2012-02-01

Leber\\'s hereditary optic neuropathy (LHON) is a maternally inherited disorder, typically presenting in the second and third decade. We report the case of an elderly gentleman with significant vascular risk factors, presenting with slowly progressive, bilateral, visual loss with high signal lesions in the pericallosal and periventricular deep white matter on MRI brain studies. Possible diagnoses included late-onset MS, ischaemic optic neuropathies, a mitochondrial disorder or an overlap syndrome such as Harding\\'s disease.

IACHEC CROSS-CALIBRATION OF CHANDRA , NuSTAR , SWIFT , SUZAKU , XMM-NEWTON WITH 3C 273 ANDPKS 2155-304

Energy Technology Data Exchange (ETDEWEB)

Madsen, Kristin K.; Forster, Karl [Cahill Center for Astronomy and Astrophysics, California Institute of Technology, Pasadena, CA 91125 (United States); Beardmore, Andrew P.; Page, Kim L. [X-ray and Observational Astronomy Group, Department of Physics and Astronomy, University of Leicester, Leicester LE1 7RH (United Kingdom); Guainazzi, Matteo [Japan Aerospace Exploration Agency, Institute of Space and Astronautical Science, 3-1-1, Yoshinodai, Sagamihara, Kanagawa, 252-5201 (Japan); Marshall, Herman L.; Miller, Eric D. [Kavli Institute for Astrophysics and Space Research, Massachusetts Institute of Technology, 77 Massachusetts Ave., Cambridge, MA 02139 (United States); Stuhlinger, Martin [European Space Astronomy Centre (ESAC), P.O. Box 78, E-28691 Villanueva de la Caada, Madrid (Spain)

2017-01-01

On behalf of the International Astronomical Consortium for High Energy Calibration, we present results from the cross-calibration campaigns in 2012 on 3C 273 and in 2013 on PKS 2155-304 between the then active X-ray observatories Chandra , NuSTAR , Suzaku , Swift, and XMM-Newton . We compare measured fluxes between instrument pairs in two energy bands, 1–5 keV and 3–7 keV, and calculate an average cross-normalization constant for each energy range. We review known cross-calibration features and provide a series of tables and figures to be used for evaluating cross-normalization constants obtained from other observations with the above mentioned observatories.

ULTRA-DEEP GEMINI NEAR-INFRARED OBSERVATIONS OF THE BULGE GLOBULAR CLUSTER NGC 6624

Energy Technology Data Exchange (ETDEWEB)

Saracino, S.; Dalessandro, E.; Ferraro, F. R.; Lanzoni, B.; Miocchi, P. [Dipartimento di Fisica e Astronomia, Università di Bologna, Viale Berti Pichat 6/2, I-40127 Bologna (Italy); Geisler, D.; Mauro, F.; Cohen, R. E.; Villanova, S. [Departamento de Astronomía, Universidad de Concepción, Casilla 160-C, Concepción (Chile); Origlia, L. [INAF—Osservatorio Astronomico di Bologna, via Ranzani 1, I-40127 Bologna (Italy); Bidin, C. Moni, E-mail: sara.saracino@unibo.it [Instituto de Astronomía, Universidad Católica del Norte, Av. Angamos 0610, Antofagasta (Chile)

2016-11-20

We used ultra-deep J and K {sub s} images secured with the near-infrared (NIR) GSAOI camera assisted by the multi-conjugate adaptive optics system GeMS at the GEMINI South Telescope in Chile, to obtain a ( K {sub s} , J - K {sub s} ) color–magnitude diagram (CMD) for the bulge globular cluster NGC 6624. We obtained the deepest and most accurate NIR CMD from the ground for this cluster, by reaching K {sub s} ∼ 21.5, approximately 8 mag below the horizontal branch level. The entire extension of the Main Sequence (MS) is nicely sampled and at K {sub s} ∼ 20 we detected the so-called MS “knee” in a purely NIR CMD. By taking advantage of the exquisite quality of the data, we estimated the absolute age of NGC 6624 ( t {sub age} = 12.0 ± 0.5 Gyr), which turns out to be in good agreement with previous studies in the literature. We also analyzed the luminosity and mass functions of MS stars down to M ∼ 0.45 M{sub ⊙}, finding evidence of a significant increase of low-mass stars at increasing distances from the cluster center. This is a clear signature of mass segregation, confirming that NGC 6624 is in an advanced stage of dynamical evolution.

Metabolomic and elemental analysis of camel and bovine urine by GC-MS and ICP-MS.

Science.gov (United States)

Ahamad, Syed Rizwan; Alhaider, Abdul Qader; Raish, Mohammad; Shakeel, Faiyaz

2017-01-01

Recent studies from the author's laboratory indicated that camel urine possesses antiplatelet activity and anti-cancer activity which is not present in bovine urine. The objective of this study is to compare the volatile and elemental components of bovine and camel urine using GC-MS and ICP-MS analysis. We are interested to know the component that performs these biological activities. The freeze dried urine was dissolved in dichloromethane and then derivatization process followed by using BSTFA for GC-MS analysis. Thirty different compounds were analyzed by the derivatization process in full scan mode. For ICP-MS analysis twenty eight important elements were analyzed in both bovine and camel urine. The results of GC-MS and ICP-MS analysis showed marked difference in the urinary metabolites. GC-MS evaluation of camel urine finds a lot of products of metabolism like benzene propanoic acid derivatives, fatty acid derivatives, amino acid derivatives, sugars, prostaglandins and canavanine. Several research reports reveal the metabolomics studies on camel urine but none of them completely reported the pharmacology related metabolomics. The present data of GC-MS suggest and support the previous studies and activities related to camel urine.

Application of LC–MS/MS for quantitative analysis of glucocorticoids and stimulants in biological fluids

OpenAIRE

Haneef, Jamshed; Shaharyar, Mohammad; Husain, Asif; Rashid, Mohd; Mishra, Ravinesh; Parveen, Shama; Ahmed, Niyaz; Pal, Manoj; Kumar, Deepak

2013-01-01

Liquid chromatography tandem mass chromatography (LCâMS/MS) is an important hyphenated technique for quantitative analysis of drugs in biological fluids. Because of high sensitivity and selectivity, LCâMS/MS has been used for pharmacokinetic studies, metabolites identification in the plasma and urine. This manuscript gives comprehensive analytical review, focusing on chromatographic separation approaches (column packing materials, column length and mobile phase) as well as different acquisiti...

Application of LC–MS/MS for quantitative analysis of glucocorticoids and stimulants in biological fluids

OpenAIRE

Haneef, Jamshed; Shaharyar, Mohammad; Husain, Asif; Rashid, Mohd; Mishra, Ravinesh; Parveen, Shama; Ahmed, Niyaz; Pal, Manoj; Kumar, Deepak

2013-01-01

Liquid chromatography tandem mass chromatography (LC–MS/MS) is an important hyphenated technique for quantitative analysis of drugs in biological fluids. Because of high sensitivity and selectivity, LC–MS/MS has been used for pharmacokinetic studies, metabolites identification in the plasma and urine. This manuscript gives comprehensive analytical review, focusing on chromatographic separation approaches (column packing materials, column length and mobile phase) as well as different acquisiti...

Chandra ACIS-S imaging spectroscopy of anomalously faint X-ray emission from Comet 103P/Hartley 2 during the EPOXI encounter

Science.gov (United States)

Lisse, C. M.; Christian, D. J.; Wolk, S. J.; Dennerl, K.; Bodewits, D.; Combi, M. R.; Lepri, S. T.; Zurbuchen, T. H.; Li, J. Y.; Dello-Russo, N.; Belton, M. J. S.; Knight, M. M.

2013-02-01

We present results from the Chandra X-ray Observatory's characterization of the X-ray emission from Comet 103P/Hartley 2, in support of NASA's Deep Impact Extended close flyby of the comet on 04 November 2010. The comet was observed 4 times for a total on target time of ˜60 ks between the 17th of October and 16th of November 2010, with two of the visits occurring during the EPOXI close approach on 04 November and 05 November 2010. X-ray emission from 103P was qualitatively similar to that observed for collisionally thin Comets 2P/Encke (Lisse, C.M. et al. [2005]. Astrophys. J. 635, 1329-1347) and 9P/Tempel 1 (Lisse, C.M. et al. [2007]. Icarus 190, 391-405). Emission morphology offset sunward but asymmetrical from the nucleus and emission lines produced by charge exchange between highly stripped C, N, and O solar wind minor ions and coma neutral gas species were found. The comet was very under-luminous in the X-ray at all times, representing the 3rd faintest comet ever detected (LX = 1.1 ± 0.3 × 1014 erg s-1). The coma was collisionally thin to the solar wind at all times, allowing solar wind ions to flow into the inner coma and interact with the densest neutral coma gas. Localization of the X-ray emission in the regions of the major rotating gas jets was observed, consistent with the major source of cometary neutral gas species being icy coma dust particles. Variable spectral features due to changing solar wind flux densities and charge states were also seen. Modeling of the Chandra observations from the first three visits using observed gas production rates and ACE solar wind ion fluxes with a charge exchange mechanism for the emission is consistent with the temporal and spectral behavior expected for a slow, hot wind typical of low latitude emission from the solar corona interacting with the comet's neutral coma. The X-ray emission during the 4th visit on 16 November 2010 is similar to the unusual behavior seen for Comet 17P/Holmes in 2007 (Christian, D.J. et

Improved LC-MS/MS method for the quantification of hepcidin-25 in clinical samples.

Science.gov (United States)

Abbas, Ioana M; Hoffmann, Holger; Montes-Bayón, María; Weller, Michael G

2018-06-01

Mass spectrometry-based methods play a crucial role in the quantification of the main iron metabolism regulator hepcidin by singling out the bioactive 25-residue peptide from the other naturally occurring N-truncated isoforms (hepcidin-20, -22, -24), which seem to be inactive in iron homeostasis. However, several difficulties arise in the MS analysis of hepcidin due to the "sticky" character of the peptide and the lack of suitable standards. Here, we propose the use of amino- and fluoro-silanized autosampler vials to reduce hepcidin interaction to laboratory glassware surfaces after testing several types of vials for the preparation of stock solutions and serum samples for isotope dilution liquid chromatography-tandem mass spectrometry (ID-LC-MS/MS). Furthermore, we have investigated two sample preparation strategies and two chromatographic separation conditions with the aim of developing a LC-MS/MS method for the sensitive and reliable quantification of hepcidin-25 in serum samples. A chromatographic separation based on usual acidic mobile phases was compared with a novel approach involving the separation of hepcidin-25 with solvents at high pH containing 0.1% of ammonia. Both methods were applied to clinical samples in an intra-laboratory comparison of two LC-MS/MS methods using the same hepcidin-25 calibrators with good correlation of the results. Finally, we recommend a LC-MS/MS-based quantification method with a dynamic range of 0.5-40 μg/L for the assessment of hepcidin-25 in human serum that uses TFA-based mobile phases and silanized glass vials. Graphical abstract Structure of hepcidin-25 (Protein Data Bank, PDB ID 2KEF).

Relapsing-Remitting MS (RRMS)

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A DEEP CHANDRA ACIS STUDY OF NGC 4151. I. THE X-RAY MORPHOLOGY OF THE 3 kpc DIAMETER CIRCUM-NUCLEAR REGION AND RELATION TO THE COLD INTERSTELLAR MEDIUM

International Nuclear Information System (INIS)

Wang Junfeng; Fabbiano, Giuseppina; Risaliti, Guido; Elvis, Martin; Karovska, Margarita; Zezas, Andreas; Mundell, Carole G.; Dumas, Gaelle; Schinnerer, Eva

2011-01-01

We report on the imaging analysis of ∼200 ks sub-arcsecond resolution Chandra Advanced CCD Imaging Spectrometer (ACIS-S) observations of the nearby Seyfert 1 galaxy NGC 4151. Bright, structured soft X-ray emission is observed to extend from 30 pc to 1.3 kpc in the southwest from the nucleus, much farther than seen in earlier X-ray studies. The terminus of the northeastern X-ray emission is spatially coincident with a CO gas lane, where the outflow likely encounters dense gas in the host galactic disk. X-ray emission is also detected outside the boundaries of the ionization cone, which indicates that the gas there is not completely shielded from the nuclear continuum, as would be the case for a molecular torus collimating the bicone. In the central r 2 emission and dusty spirals we find in an Hubble Space Telescope V - H color image. The agreement between the observed H 2 line flux and the value predicted from X-ray-irradiated molecular cloud models supports photo-excitation by X-rays from the active nucleus as the origin of the H 2 line, although contribution from UV fluorescence or collisional excitation cannot be ruled out with current data. The discrepancy between the mass of cold molecular gas inferred from recent CO and near-infrared H 2 observations may be explained by the anomalous CO abundance in this X-ray-dominated region. The total H 2 mass derived from the X-ray observation agrees with the recent measurement by Storchi-Bergmann et al.

The EIPeptiDi tool: enhancing peptide discovery in ICAT-based LC MS/MS experiments

Directory of Open Access Journals (Sweden)

Tradigo Giuseppe

2007-07-01

Full Text Available Abstract Background Isotope-coded affinity tags (ICAT is a method for quantitative proteomics based on differential isotopic labeling, sample digestion and mass spectrometry (MS. The method allows the identification and relative quantification of proteins present in two samples and consists of the following phases. First, cysteine residues are either labeled using the ICAT Light or ICAT Heavy reagent (having identical chemical properties but different masses. Then, after whole sample digestion, the labeled peptides are captured selectively using the biotin tag contained in both ICAT reagents. Finally, the simplified peptide mixture is analyzed by nanoscale liquid chromatography-tandem mass spectrometry (LC-MS/MS. Nevertheless, the ICAT LC-MS/MS method still suffers from insufficient sample-to-sample reproducibility on peptide identification. In particular, the number and the type of peptides identified in different experiments can vary considerably and, thus, the statistical (comparative analysis of sample sets is very challenging. Low information overlap at the peptide and, consequently, at the protein level, is very detrimental in situations where the number of samples to be analyzed is high. Results We designed a method for improving the data processing and peptide identification in sample sets subjected to ICAT labeling and LC-MS/MS analysis, based on cross validating MS/MS results. Such a method has been implemented in a tool, called EIPeptiDi, which boosts the ICAT data analysis software improving peptide identification throughout the input data set. Heavy/Light (H/L pairs quantified but not identified by the MS/MS routine, are assigned to peptide sequences identified in other samples, by using similarity criteria based on chromatographic retention time and Heavy/Light mass attributes. EIPeptiDi significantly improves the number of identified peptides per sample, proving that the proposed method has a considerable impact on the protein

Isotope ratio monitoring LC/MS (IRM-LC/MS): new applications

International Nuclear Information System (INIS)

Juchelka, D; Hilkert, A.; Krummen, M.

2005-01-01

With the introduction of compound specific isotope analysis by isotope ratio monitoring GC/ MS (IRM-GC/MS) the immediate demand for similar applications using HPLC was created. Many compounds of biological, medical, pharmaceutical and environmental interest are not volatile or too polar. Consequently, they cannot be directly analyzed by gas chromatography. In IRM-GC/MS the carrier is helium, which does not interfere with the essential combust ion step prior to isotope ratio mass spectrometry (IRMS). In opposite the LC mobile phase has inhibited a similar direct conversion up to now. All earlier IRM-LC/MS approaches were based on the removal of the liquid phase prior to combustion risking fractionation of the isotope ratios of the eluted compounds. To avoid such restrictions we developed a new continuous flow concept for the coupling of an HPLC system to the isotope ratio MS for 13 C/ 12C isotope ratio analysis. In the Finnigan LC IsoLink, the liquid phase is not removed from the sample prior to oxidation. The sample is oxidized still in the mobile phase followed by on-line separation of the CO 2 from the liquid phase and transfer into the isotope ratio MS. Therefore, this strategy is based on water and inorganic buffers as mobile phase. The new approach opens up a whole new world in the application of gas isotope ratio mass spectrometry. The 13 C/ 12 C ratio s of organic acids, amino acids, carbohydrates and nucleotides can now be measured. These components typically within a complex matrix are separated by liquid chromatography followed by on-line determination of the isotope ratios. The draw backs of using derivatization and off-line preparation procedures can now be over come. This new technique allow s studying biochemical cycles, running tracer experiments and determining the origin of components. Applications from different scientific areas such as biogeochemistry, molecular biology, and pharmacy as well as authenticity control o f foods will be presented

Ms. Mentor Unmasked

Science.gov (United States)

Krebs, Paula

2008-01-01

This article presents an interview with Emily Toth, who writes the monthly "Ms. Mentor" academic advice column in the "Chronicle of Higher Education" and teaches in the English department at Louisiana State University, in Baton Rouge. She is the author of "Ms. Mentor's Impeccable Advice for Women in Academia" (1997), "Inside Peyton Place: The Life…

Relapsing-Remitting MS (RRMS)

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Deep iCrawl: An Intelligent Vision-Based Deep Web Crawler

OpenAIRE

R.Anita; V.Ganga Bharani; N.Nityanandam; Pradeep Kumar Sahoo

2011-01-01

The explosive growth of World Wide Web has posed a challenging problem in extracting relevant data. Traditional web crawlers focus only on the surface web while the deep web keeps expanding behind the scene. Deep web pages are created dynamically as a result of queries posed to specific web databases. The structure of the deep web pages makes it impossible for traditional web crawlers to access deep web contents. This paper, Deep iCrawl, gives a novel and vision-based app...

Lung Cancer Serum Biomarker Discovery Using Label Free LC-MS/MS

Science.gov (United States)

Zeng, Xuemei; Hood, Brian L.; Zhao, Ting; Conrads, Thomas P.; Sun, Mai; Gopalakrishnan, Vanathi; Grover, Himanshu; Day, Roger S.; Weissfeld, Joel L.; Wilson, David O.; Siegfried, Jill M.; Bigbee, William L.

2011-01-01

Introduction Lung cancer remains the leading cause of cancer-related death with poor survival due to the late stage at which lung cancer is typically diagnosed. Given the clinical burden from lung cancer, and the relatively favorable survival associated with early stage lung cancer, biomarkers for early detection of lung cancer are of important potential clinical benefit. Methods We performed a global lung cancer serum biomarker discovery study using liquid chromatography-tandem mass spectrometry (LC-MS/MS) in a set of pooled non-small cell lung cancer (NSCLC) case sera and matched controls. Immunoaffinity subtraction was used to deplete the top most abundant serum proteins; the remaining serum proteins were subjected to trypsin digestion and analyzed in triplicate by LC-MS/MS. The tandem mass spectrum data were searched against the human proteome database and the resultant spectral counting data were used to estimate the relative abundance of proteins across the case/control serum pools. The spectral counting derived abundances of some candidate biomarker proteins were confirmed with multiple reaction monitoring MS assays. Results A list of 49 differentially abundant candidate proteins was compiled by applying a negative binomial regression model to the spectral counting data (pbiomarkers with statistically significant differential abundance across the lung cancer case/control pools which, when validated, could improve lung cancer early detection. PMID:21304412

Relapsing-Remitting MS (RRMS)

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Full Text Available ... Treating MS Comprehensive Care Find an MS Care Provider Medications Managing Relapses Rehabilitation Complementary & Alternative Medicines For Clinicians Resources & Support Library & Education Programs Find Support Advanced Care ...

Picocyanobacteria and deep-ocean fluorescent dissolved organic matter share similar optical properties

Science.gov (United States)

Zhao, Zhao; Gonsior, Michael; Luek, Jenna; Timko, Stephen; Ianiri, Hope; Hertkorn, Norbert; Schmitt-Kopplin, Philippe; Fang, Xiaoting; Zeng, Qinglu; Jiao, Nianzhi; Chen, Feng

2017-05-01

Marine chromophoric dissolved organic matter (CDOM) and its related fluorescent components (FDOM), which are widely distributed but highly photobleached in the surface ocean, are critical in regulating light attenuation in the ocean. However, the origins of marine FDOM are still under investigation. Here we show that cultured picocyanobacteria, Synechococcus and Prochlorococcus, release FDOM that closely match the typical fluorescent signals found in oceanic environments. Picocyanobacterial FDOM also shows comparable apparent fluorescent quantum yields and undergoes similar photo-degradation behaviour when compared with deep-ocean FDOM, further strengthening the similarity between them. Ultrahigh-resolution mass spectrometry (MS) and nuclear magnetic resonance spectroscopy reveal abundant nitrogen-containing compounds in Synechococcus DOM, which may originate from degradation products of the fluorescent phycobilin pigments. Given the importance of picocyanobacteria in the global carbon cycle, our results indicate that picocyanobacteria are likely to be important sources of marine autochthonous FDOM, which may accumulate in the deep ocean.

Cortical Plasticity Induction by Pairing Subthalamic Nucleus Deep-Brain Stimulation and Primary Motor Cortical Transcranial Magnetic Stimulation in Parkinson's Disease.

Science.gov (United States)

Udupa, Kaviraja; Bahl, Nina; Ni, Zhen; Gunraj, Carolyn; Mazzella, Filomena; Moro, Elena; Hodaie, Mojgan; Lozano, Andres M; Lang, Anthony E; Chen, Robert

2016-01-13

Noninvasive brain stimulation studies have shown abnormal motor cortical plasticity in Parkinson's disease (PD). These studies used peripheral nerve stimulation paired with transcranial magnetic stimulation (TMS) to primary motor cortex (M1) at specific intervals to induce plasticity. Induction of cortical plasticity through stimulation of the basal ganglia (BG)-M1 connections has not been studied. In the present study, we used a novel technique of plasticity induction by repeated pairing of deep-brain stimulation (DBS) of the BG with M1 stimulation using TMS. We hypothesize that repeated pairing of subthalamic nucleus (STN)-DBS and M1-TMS at specific time intervals will lead to plasticity in the M1. Ten PD human patients with STN-DBS were studied in the on-medication state with DBS set to 3 Hz. The interstimulus intervals (ISIs) between STN-DBS and TMS that produced cortical facilitation were determined individually for each patient. Three plasticity induction conditions with repeated pairings (180 times) at specific ISIs (∼ 3 and ∼ 23 ms) that produced cortical facilitation and a control ISI of 167 ms were tested in random order. Repeated pairing of STN-DBS and M1-TMS at short (∼ 3 ms) and medium (∼ 23 ms) latencies increased M1 excitability that lasted for at least 45 min, whereas the control condition (fixed ISI of 167 ms) had no effect. There were no specific changes in motor thresholds, intracortical circuits, or recruitment curves. Our results indicate that paired-associative cortical plasticity can be induced by repeated STN and M1 stimulation at specific intervals. These results show that STN-DBS can modulate cortical plasticity. We introduced a new experimental paradigm to test the hypothesis that pairing subthalamic nucleus deep-brain stimulation (STN-DBS) with motor cortical transcranial magnetic stimulation (M1-TMS) at specific times can induce cortical plasticity in patients with Parkinson's disease (PD). We found that repeated pairing of STN

Progressive-Relapsing MS (PRMS)

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... Is MS? Types of MS Share this page Facebook Twitter Email ... multiple sclerosis (PRMS) was described in the 1996 disease-course definitions as — steadily worsening neurologic function from the beginning ...

EPA CRL MS014: Analysis of Aldicarb, Bromadiolone, Carbofuran, Oxamyl and Methomyl in Water by Multiple Reaction Monitoring Liquid Chromatography / Tandem Mass Spectrometry (LC/MS/MS)

Science.gov (United States)

Method MS014 describes procedures for solvent extraction of aldicarb, bromadiolone, carbofuran, oxamyl and methomyl from water samples, followed by analysis using liquid chromatography tandem mass spectrometry (LC-MS-MS).

Application of LC–MS/MS for quantitative analysis of glucocorticoids and stimulants in biological fluids

Directory of Open Access Journals (Sweden)

Jamshed Haneef

2013-10-01

Full Text Available Liquid chromatography tandem mass chromatography (LC–MS/MS is an important hyphenated technique for quantitative analysis of drugs in biological fluids. Because of high sensitivity and selectivity, LC–MS/MS has been used for pharmacokinetic studies, metabolites identification in the plasma and urine. This manuscript gives comprehensive analytical review, focusing on chromatographic separation approaches (column packing materials, column length and mobile phase as well as different acquisition modes (SIM, MRM for quantitative analysis of glucocorticoids and stimulants. This review is not meant to be exhaustive but rather to provide a general overview for detection and confirmation of target drugs using LC–MS/MS and thus useful in the doping analysis, toxicological studies as well as in pharmaceutical analysis. Keywords: LC–MS/MS, Ionization techniques, Glucocorticoids, Stimulants, Hyphenated techniques, Biological fluid

CHANDRA, KECK, AND VLA OBSERVATIONS OF THE CRAB NEBULA DURING THE 2011-APRIL GAMMA-RAY FLARE

Energy Technology Data Exchange (ETDEWEB)

Weisskopf, Martin C.; Tennant, Allyn F.; O' Dell, Stephen L. [NASA Marshall Space Flight Center, Astrophysics Office (ZP12), Huntsville, AL 35812 (United States); Arons, Jonathan [Astronomy Department and Theoretical Astrophysics Center, University of California, Berkeley, 601 Campbell Hall, Berkeley, CA 94720 (United States); Blandford, Roger; Funk, Stefan; Romani, Roger W. [W. W. Hansen Experimental Physics Laboratory, Kavli Institute for Particle Astrophysics and Cosmology, Department of Physics and SLAC National Accelerator Laboratory, Stanford University, Stanford, CA 94305 (United States); Buehler, Rolf [DESY, Platanenallee 6, D-15738 Zeuthen (Germany); Caraveo, Patrizia; De Luca, Andrea [INAF-IASF Milano, via E. Bassini 15, I-20133 Milano (Italy); Cheung, Chi C. [National Research Council Research Associate, National Academy of Sciences, Washington, DC 20001 (United States); Costa, Enrico [INFN Roma Tor Vergata, via della Ricerca Scientifica 1, I-00133 Roma (Italy); Ferrigno, Carlo [ISDC, Data Center for Astrophysics of the University of Geneva, chemin d' cogia 16, CH-1290 Versoix (Switzerland); Fu, Hai [Department of Physics and Astronomy, University of California, Irvine, CA 92697 (United States); Habermehl, Moritz; Horns, Dieter [Institut fuer Experimentalphysik, Universitaet Hamburg, Luruper Chaussee 149, D-22761 Hamburg (Germany); Linford, Justin D. [Department of Physics and Astronomy, University of New Mexico, MSC07 4220, Albuquerque, NM 87131-0001 (United States); Lobanov, Andrei [Max-Planck-Institut fuer Radioastronomie, Auf dem Huegel 69, D-53121 Bonn (Germany); Max, Claire [Department of Astronomy and Astrophysics, University of California, Santa Cruz, CA 95064 (United States); Mignani, Roberto [Mullard Space Science Laboratory, University College London, Holmbury St. Mary Dorking, Surrey RH5 6NT (United Kingdom); and others

2013-03-01

We present results from our analysis of Chandra X-Ray Observatory, W. M. Keck Observatory, and Karl G. Jansky Very Large Array (VLA) images of the Crab Nebula that were contemporaneous with the {gamma}-ray flare of 2011 April. Despite hints in the X-ray data, we find no evidence for statistically significant variations that pinpoint the specific location of the flares within the Nebula. The Keck observations extend this conclusion to the 'inner knot', i.e., the feature within an arcsecond of the pulsar. The VLA observations support this conclusion. We also discuss theoretical implications of the {gamma}-ray flares and suggest that the most dramatic {gamma}-ray flares are due to radiation-reaction-limited synchrotron emission associated with sudden, dissipative changes in the current system sustained by the central pulsar.

MS Windows domēna darbstacijas migrācijas iespējas no MS Windows XP uz MS Windows 7.

OpenAIRE

Zariņš, Valdis

2009-01-01

Kvalifikācijas darbā tiek aprakstītas MS Windows domēna darbstacijas migrācijas iespējas no MS Windows XP uz MS Windows 7, kā servera operētājsistēmas izmantojot tādus Microsoft produktus, kā Microsoft Windows Server 2003 un Microsoft Windows Server 2008. Kvalifikācijas darba teorētiskaja daļā tiek apskatīti Microsoft Windows 7 priekšrocības un uzlabojumus gan no darbstacijas lietotāja , gan no darbstacijas administratora puses. Ir aprakstītas Microsoft Windows Server 2008 jauninājumu ie...

RESOLVING THE ξ BOO BINARY WITH CHANDRA, AND REVEALING THE SPECTRAL TYPE DEPENDENCE OF THE CORONAL 'FIP EFFECT'

International Nuclear Information System (INIS)

Wood, Brian E.; Linsky, Jeffrey L.

2010-01-01

On 2008 May 2, Chandra observed the X-ray spectrum of ξ Boo (G8 V+K4 V), resolving the binary for the first time in X-rays and allowing the coronae of the two stars to be studied separately. With the contributions of ξ Boo A and B to the system's total X-ray emission now observationally established (88.5% and 11.5%, respectively), consideration of mass loss measurements for GK dwarfs of various activity levels (including one for ξ Boo) leads to the surprising conclusion that ξ Boo B may dominate the wind from the binary, with ξ Boo A's wind being very weak despite its active corona. Emission measure (EM) distributions and coronal abundances are computed for both stars and compared with Chandra measurements of other moderately active stars with G8-K5 spectral types, all of which exhibit a narrow peak in EM near log T = 6.6, indicating that the coronal heating process in these stars has a strong preference for this temperature. As is the case for the Sun and many other stars, our sample of stars shows coronal abundance anomalies dependent on the first ionization potential (FIP) of the element. We see no dependence of the degree of 'FIP effect' on activity, but there is a dependence on spectral type, a correlation that becomes more convincing when moderately active main-sequence stars with a broader range of spectral types are considered. This clear dependence of coronal abundances on spectral type weakens if the stellar sample is allowed to be contaminated by evolved stars, interacting binaries, or extremely active stars with log L X >29, explaining why this correlation has not been recognized in the past.

Resolving the xi Boo Binary with Chandra, and Revealing the Spectral Type Dependence of the Coronal "Fip Effect"

Science.gov (United States)

Wood, Brian E.; Linsky, Jeffrey L.

2010-01-01

On 2008 May 2, Chandra observed the X-ray spectrum of xi Boo (G8 V+K4 V), resolving the binary for the first time in X-rays and allowing the coronae of the two stars to be studied separately. With the contributions of ξ Boo A and B to the system's total X-ray emission now observationally established (88.5% and 11.5% respectively), consideration of mass loss measurements for GK dwarfs of various activity levels (including one for xi Boo) leads to the surprising conclusion that xi Boo B may dominate the wind from the binary, with xi Boo A's wind being very weak despite its active corona. Emission measure (EM) distributions and coronal abundances are computed for both stars and compared with Chandra measurements of other moderately active stars with G8-K5 spectral types, all of which exhibit a narrow peak in EM near log T = 6.6, indicating that the coronal heating process in these stars has a strong preference for this temperature. As is the case for the Sun and many other stars, our sample of stars shows coronal abundance anomalies dependent on the first ionization potential (FIP) of the element. We see no dependence of the degree of FIP effect on activity, but there is a dependence on spectral type, a correlation that becomes more convincing when moderately active main-sequence stars with a broader range of spectral types are considered. This clear dependence of coronal abundances on spectral type weakens if the stellar sample is allowed to be contaminated by evolved stars, interacting binaries or extremely active stars with logLX 29, explaining why this correlation has not been recognized in the past.

Relapsing-Remitting MS (RRMS)

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Full Text Available ... Contact Us Newly Diagnosed If you or somone close to you has recently been diagnosed, access our MS information and resources. Start ... Room MS Prevalence Charitable Ratings Corporate Support Helpful Links ...

MS in Your Relationships

Science.gov (United States)

... MS Relationships Share this page Facebook Twitter Email Relationships MS poses additional challenges, but it also enriches ... when it is not. Keeping balance in your relationship When one person in a couple is affected ...

CORRELATION OF CHANDRA PHOTONS WITH THE RADIO GIANT PULSES FROM THE CRAB PULSAR

International Nuclear Information System (INIS)

Bilous, A. V.; McLaughlin, M. A.; Kondratiev, V. I.; Ransom, S. M.

2012-01-01

No apparent correlation was found between giant pulses (GPs) and X-ray photons from the Crab pulsar during 5.4 hr of simultaneous observations with the Green Bank Telescope at 1.5 GHz and Chandra X-Ray Observatory primarily in the energy range of 1.5-4.5 keV. During the Crab pulsar periods with GPs, the X-ray flux in radio emission phase windows does not change more than by ±10% for main pulse (MP) GPs and ±30% for interpulse (IP) GPs. During GPs themselves, the X-ray flux does not change by more than two times for MP GPs and five times for IP GPs. All limits quoted are compatible with 2σ fluctuations of the X-ray flux around the sets of false GPs with random arrival times. The results speak in favor of changes in plasma coherence as the origin of GPs. However, the results do not rule out variations in the rate of particle creation if the particles that emit coherent radio emission are mostly at the lowest Landau level.

Single-cell analysis by ICP-MS/MS as a fast tool for cellular bioavailability studies of arsenite.

Science.gov (United States)

Meyer, S; López-Serrano, A; Mitze, H; Jakubowski, N; Schwerdtle, T

2018-01-24

Single-cell inductively coupled plasma mass spectrometry (SC-ICP-MS) has become a powerful and fast tool to evaluate the elemental composition at a single-cell level. In this study, the cellular bioavailability of arsenite (incubation of 25 and 50 μM for 0-48 h) has been successfully assessed by SC-ICP-MS/MS for the first time directly after re-suspending the cells in water. This procedure avoids the normally arising cell membrane permeabilization caused by cell fixation methods (e.g. methanol fixation). The reliability and feasibility of this SC-ICP-MS/MS approach with a limit of detection of 0.35 fg per cell was validated by conventional bulk ICP-MS/MS analysis after cell digestion and parallel measurement of sulfur and phosphorus.

An impulse-driven liquid-droplet deposition interface for combining LC with MALDI MS and MS/MS.

Science.gov (United States)

Young, J Bryce; Li, Liang

2006-03-01

A simple and robust impulse-driven droplet deposition system was developed for off-line liquid chromatography matrix-assisted laser desorption ionization mass spectrometry (LC-MALDI MS). The system uses a solenoid operated with a pulsed voltage power supply to generate impulses that dislodge the hanging droplets from the LC outlet directly to a MALDI plate via a momentum transfer process. There is no contact between the LC outlet and the collection surface. The system is compatible with solvents of varying polarity and viscosity, and accommodates the use of hydrophobic and hydrophilic MALDI matrices. MALDI spots are produced on-line with the separation, and do not require further processing before MS analysis. It is shown that high quality MALDI spectra from 5 fmol of pyro-Glu-fibrinopeptide deposition after LC separation could be obtained using the device, indicating that there was no sample loss in the interface. To demonstrate the analytical performance of the system as a proteome analysis tool, a range of BSA digest concentrations covering about 3 orders of magnitude, from 5 fmol to 1 pmol, were analyzed by LC-MALDI quadrupole time-of-flight MS, yielding 6 and 57% amino acid sequence coverage, respectively. In addition, a complex protein mixture of an E. coli cell extract was tryptically digested and analyzed by LC-MALDI MS, resulting in the detection of a total of 409 unique peptides from 100 fractions of 15-s intervals.

SWATH Mass Spectrometry Performance Using Extended Peptide MS/MS Assay Libraries*

Science.gov (United States)

Wu, Jemma X.; Song, Xiaomin; Pascovici, Dana; Zaw, Thiri; Care, Natasha; Krisp, Christoph; Molloy, Mark P.

2016-01-01

The use of data-independent acquisition methods such as SWATH for mass spectrometry based proteomics is usually performed with peptide MS/MS assay libraries which enable identification and quantitation of peptide peak areas. Reference assay libraries can be generated locally through information dependent acquisition, or obtained from community data repositories for commonly studied organisms. However, there have been no studies performed to systematically evaluate how locally generated or repository-based assay libraries affect SWATH performance for proteomic studies. To undertake this analysis, we developed a software workflow, SwathXtend, which generates extended peptide assay libraries by integration with a local seed library and delivers statistical analysis of SWATH-quantitative comparisons. We designed test samples using peptides from a yeast extract spiked into peptides from human K562 cell lysates at three different ratios to simulate protein abundance change comparisons. SWATH-MS performance was assessed using local and external assay libraries of varying complexities and proteome compositions. These experiments demonstrated that local seed libraries integrated with external assay libraries achieve better performance than local assay libraries alone, in terms of the number of identified peptides and proteins and the specificity to detect differentially abundant proteins. Our findings show that the performance of extended assay libraries is influenced by the MS/MS feature similarity of the seed and external libraries, while statistical analysis using multiple testing corrections increases the statistical rigor needed when searching against large extended assay libraries. PMID:27161445

LC-MS/MS Peptide Mapping with Automated Data Processing for Routine Profiling of N-Glycans in Immunoglobulins

Science.gov (United States)

Shah, Bhavana; Jiang, Xinzhao Grace; Chen, Louise; Zhang, Zhongqi

2014-06-01

Protein N-Glycan analysis is traditionally performed by high pH anion exchange chromatography (HPAEC), reversed phase liquid chromatography (RPLC), or hydrophilic interaction liquid chromatography (HILIC) on fluorescence-labeled glycans enzymatically released from the glycoprotein. These methods require time-consuming sample preparations and do not provide site-specific glycosylation information. Liquid chromatography-tandem mass spectrometry (LC-MS/MS) peptide mapping is frequently used for protein structural characterization and, as a bonus, can potentially provide glycan profile on each individual glycosylation site. In this work, a recently developed glycopeptide fragmentation model was used for automated identification, based on their MS/MS, of N-glycopeptides from proteolytic digestion of monoclonal antibodies (mAbs). Experimental conditions were optimized to achieve accurate profiling of glycoforms. Glycan profiles obtained from LC-MS/MS peptide mapping were compared with those obtained from HPAEC, RPLC, and HILIC analyses of released glycans for several mAb molecules. Accuracy, reproducibility, and linearity of the LC-MS/MS peptide mapping method for glycan profiling were evaluated. The LC-MS/MS peptide mapping method with fully automated data analysis requires less sample preparation, provides site-specific information, and may serve as an alternative method for routine profiling of N-glycans on immunoglobulins as well as other glycoproteins with simple N-glycans.

The properties of Hα emission-line galaxies at z = 2.24

International Nuclear Information System (INIS)

An, Fang Xia; Zheng, Xian Zhong; Wang, Wei-Hao; Huang, Jia-Sheng; Kong, Xu; Wang, Jun-Xian; Zhu, Feifan; Fang, Guan Wen; Gu, Qiu-Sheng; Wu, Hong; Hao, Lei; Xia, Xiao-Yang

2014-01-01

Using deep narrowband H 2 S1 and K s -band imaging data obtained with CFHT/WIRCam, we identify a sample of 56 Hα emission-line galaxies (ELGs) at z = 2.24 with the 5σ depths of H 2 S1 = 22.8 and K s = 24.8 (AB) over a 383 arcmin 2 area in the Extended Chandra Deep Field South. A detailed analysis is carried out with existing multi-wavelength data in this field. Three of the 56 Hα ELGs are detected in Chandra 4 Ms X-ray observations and two of them are classified as active galactic nuclei. The rest-frame UV and optical morphologies revealed by HST/ACS and WFC3 deep images show that nearly half of the Hα ELGs are either merging systems or have a close companion, indicating that the merging/interacting processes play a key role in regulating star formation at cosmic epoch z = 2-3. About 14% are too faint to be resolved in the rest-frame UV morphology due to high dust extinction. We estimate dust extinction from spectral energy distributions. We find that dust extinction is generally correlated with Hα luminosity and stellar mass. Our results suggest that Hα ELGs are representative of star-forming galaxies. Applying extinction corrections to individual objects, we examine the intrinsic Hα luminosity function (LF) at z = 2.24, obtaining a best-fit Schechter function characterized by a faint-end slope of α = – 1.3. This is shallower than the typical slope of α ≅ –1.6 in previous works based on constant extinction correction. We demonstrate that this difference is mainly due to the different extinction corrections. The proper extinction correction is thus the key to recovering the intrinsic LF as the extinction globally increases with Hα luminosity. Moreover, we find that our Hα LF mirrors the stellar mass function of star-forming galaxies at the same cosmic epoch. This finding indeed reflects the tight correlation between star formation rate and stellar mass for star-forming galaxies, i.e., the so-called main sequence.

Investigation of enrofloxacin residues in broiler tissues using ELISA and LC-MS/MS.

Science.gov (United States)

Panzenhagen, Pedro Henrique N; Aguiar, Waldemir S; Gouvêa, Raquel; de Oliveira, Andréa M G; Barreto, Fabiano; Pereira, Virgínia L A; Aquino, Maria Helena C

2016-01-01

This study investigated the efficiency of an enrofloxacin ELISA test kit to detect the presence of enrofloxacin residues in broiler tissues compared with LC-MS/MS. Broiler tissues from 72 samples consisting of 60 breast muscle, six pools of livers (500 g each) and six pools of kidneys (500 g each) were obtained from six different slaughterhouses. Breast muscle from 10 carcasses and pools of livers and kidneys from approximately 200 carcasses of the same flock were collected from each slaughterhouse. ELISA and HPLC were used to identify and quantify the contamination of the samples with enrofloxacin. A total of 72% of the analysed samples contained enrofloxacin residues detected by the ELISA and 22.2% were detected by LC-MS/MS. The mean values of enrofloxacin contamination found in chicken breast by ELISA and HPLC were 8.63 and 12.25 μg kg(-1), respectively. None of the samples exceeded the maximum limit of 100 μg kg(-1) by both methods set by the European Union as well as the Brazilian Agriculture Ministry. All positive samples for enrofloxacin residues detected by LC-MS/MS were also positive by ELISA. These data confirm the efficiency of the ELISA test, and suggest its use as a screening method for enrofloxacin residues in poultry tissues due to its quick results, low price and ease of applicability.

Relationship between plasma and salivary melatonin and cortisol investigated by LC-MS/MS.

Science.gov (United States)

van Faassen, Martijn; Bischoff, Rainer; Kema, Ido P

2017-08-28

Disturbance of the circadian rhythm has been associated with disease states, such as metabolic disorders, depression and cancer. Quantification of the circadian markers such as melatonin and cortisol critically depend on reliable and reproducible analytical methods. Previously, melatonin and cortisol were primarily analyzed separately, mainly using immunoassays. Here we describe the validation and application of a high-throughput liquid chromatography in combination with mass spectrometry (LC-MS/MS) method for the combined analysis of melatonin and cortisol in plasma and saliva. The LC-MS/MS method was validated according to international validation guidelines. We used this method to analyze total plasma, free plasma (as obtained by equilibrium dialysis) and saliva melatonin and cortisol in healthy adults. Validation results for plasma and saliva melatonin and cortisol were well within the international validation criteria. We observed no difference between saliva collected by passive drooling or Salivette. Moreover, we noted a significant difference in saliva vs. free plasma melatonin. We observed on average 36% (95% CI: 4%-60%) higher salivary melatonin levels in comparison to free plasma melatonin, suggestive of local production of melatonin in the salivary glands. The novel outcome of this study is probably due to the high precision of our LC-MS/MS assay. These outcomes illustrate the added value of accurate and sensitive mass spectrometry based methods for the quantification of neuroendocrine biomarkers.

Analytical methods for multiresidue determination of sulfonamides and trimethoprim in meat and ground water samples by CE-MS and CE-MS/MS.

Science.gov (United States)

Soto-Chinchilla, Jorge J; García-Campaña, Ana M; Gámiz-Gracia, Laura

2007-11-01

This paper presents two methods based on CZE-MS detection and CZE-MS/MS detection developed for the multiresidue determination of ten sulfonamides (sulfapyridine, sulfadoxin, sulfamethazine, sulfadimethoxine, sulfameter, sulfamerazine, sulfachlorpyridazine, sulfadiazine, sulfamethoxazole, and sulfamethizole) and a potentiator, trimethoprim (TMP), whose contents are regulated by the EU Council Regulation no. 2377/90 in animal edible tissues. Experimental designs were employed to optimize the electrospray conditions. MS/MS experiments using an IT as analyzer operating in multiple reaction monitoring (MRM) mode were carried out to achieve the minimum number of points according to the 2002/657/EC European Decision for unambiguous identification. The proposed procedures have been compared in terms of the performance characteristics and trueness. The limits of detection and quantification were in all cases lower than the maximum residue limits legislated for these compounds and the recoveries were satisfactory, being possible the application for their monitoring in foodstuff of animal origin and in environmental samples, allowing the determination of sulfonamides and TMP residues in meat and in superficial water in the low microg/L range.

Cross-validated stable-isotope dilution GC-MS and LC-MS/MS assays for monoacylglycerol lipase (MAGL) activity by measuring arachidonic acid released from the endocannabinoid 2-arachidonoyl glycerol.

Science.gov (United States)

Kayacelebi, Arslan Arinc; Schauerte, Celina; Kling, Katharina; Herbers, Jan; Beckmann, Bibiana; Engeli, Stefan; Jordan, Jens; Zoerner, Alexander A; Tsikas, Dimitrios

2017-03-15

2-Arachidonoyl glycerol (2AG) is an endocannabinoid that activates cannabinoid (CB) receptors CB1 and CB2. Monoacylglycerol lipase (MAGL) inactivates 2AG through hydrolysis to arachidonic acid (AA) and glycerol, thus modulating the activity at CB receptors. In the brain, AA released from 2AG by the action of MAGL serves as a substrate for cyclooxygenases which produce pro-inflammatory prostaglandins. Here we report stable-isotope GC-MS and LC-MS/MS assays for the reliable measurement of MAGL activity. The assays utilize deuterium-labeled 2AG (d 8 -2AG; 10μM) as the MAGL substrate and measure deuterium-labeled AA (d 8 -AA; range 0-1μM) as the MAGL product. Unlabelled AA (d 0 -AA, 1μM) serves as the internal standard. d 8 -AA and d 0 -AA are extracted from the aqueous buffered incubation mixtures by ethyl acetate. Upon solvent evaporation the residue is reconstituted in the mobile phase prior to LC-MS/MS analysis or in anhydrous acetonitrile for GC-MS analysis. LC-MS/MS analysis is performed in the negative electrospray ionization mode by selected-reaction monitoring the mass transitions [M-H] - →[M-H - CO 2 ] - , i.e., m/z 311→m/z 267 for d 8 -AA and m/z 303→m/z 259 for d 0 -AA. Prior to GC-MS analysis d 8 -AA and d 0 -AA were converted to their pentafluorobenzyl (PFB) esters by means of PFB-Br. GC-MS analysis is performed in the electron-capture negative-ion chemical ionization mode by selected-ion monitoring the ions [M-PFB] - , i.e., m/z 311 for d 8 -AA and m/z 303 for d 0 -AA. The GC-MS and LC-MS/MS assays were cross-validated. Linear regression analysis between the concentration (range, 0-1μM) of d 8 -AA measured by LC-MS/MS (y) and that by GC-MS (x) revealed a straight line (r 2 =0.9848) with the regression equation y=0.003+0.898x, indicating a good agreement. In dog liver, we detected MAGL activity that was inhibitable by the MAGL inhibitor JZL-184. Exogenous eicosatetraynoic acid is suitable as internal standard for the quantitative determination

The potential use of complex derivatization procedures in comprehensive HPLC-MS/MS detection of anabolic steroids.

Science.gov (United States)

Baranov, Pavel A; Appolonova, Svetlana A; Rodchenkov, Grigory M

2010-10-01

The use of two separate derivatization procedures with the formation of oxime (hydroxyl ammonium pretreatment) and picolinoyl (mixed anhydride method) derivates of anabolic steroids following HPLC-MS/MS analysis was proposed. The main product ions of obtained derivatives for 21 anabolic steroids were evaluated and fragmentation pathways were compared.The analysis of MS/MS spectra for underivatized steroids versus oxime or picolinoyl derivatives showed that in case of analytes containing conjugated double bonds in sterane core all of the observed MS/MS spectra contained abundant product ions of diagnostic value. The implementation of derivatization procedures to such compounds is useful for upgrading sensitivity or selectivity of the evaluated method. On the other hand, MS/MS spectra of underivatized and oxime analytes without conjugated double bonds in sterane core produce spectra with large amounts of low abundant product ions. Picolinoyl derivatives formation leads to highly specific spectra with product ions of diagnostic value coupled with sensitive and selective analysis at the same time. The intra- and inter-group comparison analysis revealed that fragmentation pathways for underivatized steroids and correspondent oxime derivatives are similar.The obtained oxime and picolinoyl derivatives provided 10-15 times higher ESI response in the HPLC-ESI-MS-selected reaction monitoring (SRM) when compared to those of underivatized molecules in positive HPLC-ESI-MS mode.Due to the laborious sample preparation we suggest to use the performed strategy for confirmation analysis purposes, metabolic studies or while the identification of new steroids or steroid-like substances. Copyright © 2010 John Wiley & Sons, Ltd.

Chandra ACIS Sub-pixel Resolution

Science.gov (United States)

Kim, Dong-Woo; Anderson, C. S.; Mossman, A. E.; Allen, G. E.; Fabbiano, G.; Glotfelty, K. J.; Karovska, M.; Kashyap, V. L.; McDowell, J. C.

2011-05-01

We investigate how to achieve the best possible ACIS spatial resolution by binning in ACIS sub-pixel and applying an event repositioning algorithm after removing pixel-randomization from the pipeline data. We quantitatively assess the improvement in spatial resolution by (1) measuring point source sizes and (2) detecting faint point sources. The size of a bright (but no pile-up), on-axis point source can be reduced by about 20-30%. With the improve resolution, we detect 20% more faint sources when embedded on the extended, diffuse emission in a crowded field. We further discuss the false source rate of about 10% among the newly detected sources, using a few ultra-deep observations. We also find that the new algorithm does not introduce a grid structure by an aliasing effect for dithered observations and does not worsen the positional accuracy

ESI MS/MS Study of Calix[4]arene Derivatives and their Metal Complexes

OpenAIRE

Benković, Tomislav; Tomišić, Vladislav; Frkanec, Leo; Galić, Nives

2012-01-01

The peptidocalixarenes 1–3 bearing tryptophan, phenylglycine and leucil units at the lower rim and their complexes with alkali-metal (Li+, Na+, K+, Rb+, Cs+) and selected lanthanide cations (La3+, Ce3+, Eu3+, Yb3+) were analyzed by ESI MS. The influences of the solvent (acetonitrile, methanol, addition of formic acid or sodium acetate) and the calixarene:cation molar ratio on signal intensities were investigated. Comprehensive MS/MS analyses were performed of all singly and doubly charged ion...

Spatially resolving a starburst galaxy at hard X-ray energies: NuSTAR, CHANDRA, AND VLBA observations of NGC 253

DEFF Research Database (Denmark)

Wik, D. R.; Lehmer, B. D.; Hornschemeier, A. E.

2014-01-01

for the first time. As a follow up to our initial study of its nuclear region, we present the first results concerning the full galaxy from simultaneous NuSTAR, Chandra, and Very Long Baseline Array monitoring of the local starburst galaxy NGC 253. Above ~10 keV, nearly all the emission is concentrated within...... is detected at E > 40 keV. We report upper limits on diffuse inverse Compton emission for a range of spatial models. For the most extended morphologies considered, these hard X-ray constraints disfavor a dominant inverse Compton component to explain the γ-ray emission detected with Fermi and H.E.S.S. If NGC...

Relapsing-Remitting MS (RRMS)

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Full Text Available ... Programs and Events Living Well with MS Diet, Exercise & Healthy Behaviors Emotional Well-Being Spiritual Well-Being ... Events d Living Well with MS d Diet, Exercise & Healthy Behaviors Diet & Nutrition Exercise Heat & Temperature Sensitivity ...

Relapsing-Remitting MS (RRMS)

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Full Text Available ... Events Living Well with MS Diet, Exercise & Healthy Behaviors Emotional Well-Being Spiritual Well-Being Cognitive Health ... Living Well with MS d Diet, Exercise & Healthy Behaviors Diet & Nutrition Exercise Heat & Temperature Sensitivity Sleep Vaccinations ...

Relapsing-Remitting MS (RRMS)

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Full Text Available ... Rule Out For Clinicians Treating MS Comprehensive Care Find an MS Care Provider Medications Managing Relapses Rehabilitation ... Medicines For Clinicians Resources & Support Library & Education Programs Find Support Advanced Care Needs Resources for Specific Populations ...

Relapsing-Remitting MS (RRMS)

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Full Text Available ... bowel and bladder problems, and problems with cognition (learning and memory or information processing). People with progressive ... More The National MS Society is Here to Help Need More Information? We Are Here Our MS ...

Relapsing-Remitting MS (RRMS)

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Full Text Available ... of Programs and Events Living Well with MS Diet, Exercise & Healthy Behaviors Emotional Well-Being Spiritual Well- ... and Events d Living Well with MS d Diet, Exercise & Healthy Behaviors Diet & Nutrition Exercise Heat & Temperature ...

Relapsing-Remitting MS (RRMS)

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Full Text Available ... d Spiritual Well-Being Building Spirituality into Your Life d Cognitive Health d Work, Home & Leisure Employment ... Partnership Opportunities d Personal Stories Ambassadors & Familiar Faces Life with MS Givers Shakers Families with MS Seekers ...

Relapsing-Remitting MS (RRMS)

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Full Text Available ... Brochure Working with MS (.pdf) Download Brochure Taming Stress (.pdf) Download Brochure Multiple Sclerosis and Your Emotions (. ... For Professionals Researchers Physicians Nurses Rehabilitation Professionals Mental Health Professionals Health and Wellness Professionals What Is MS? ...

Relapsing-Remitting MS (RRMS)

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Full Text Available ... Online d Give in Honor or Memory d Workplace Giving d Employer Matching Gifts d Gifts of ... Living with MS (.pdf) Download Brochure Focus on Employment (.pdf) Download Brochure Working with MS (.pdf) Download ...

Relapsing-Remitting MS (RRMS)

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Full Text Available ... Life d Cognitive Health d Work, Home & Leisure Employment Insurance & Financial Information Staying Mobile Reclaiming Control Accessibility ... Living with MS (.pdf) Download Brochure Focus on Employment (.pdf) Download Brochure Working with MS (.pdf) Download ...

Relapsing-Remitting MS (RRMS)

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Full Text Available ... working effectively. How does RRMS differ from progressive types of MS? While RRMS is defined by attacks ... forms of MS involve much less of this type of inflammation. People with RRMS tend to have ...

Relapsing-Remitting MS (RRMS)

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Full Text Available ... attacks of inflammation (relapses) in the CNS, progressive forms of MS involve much less of this type ... and memory or information processing). People with progressive forms of MS are more likely to experience gradually ...

Relapsing-Remitting MS (RRMS)

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Full Text Available ... Associated Myelopathy (HAM) Neuromyelitis Optica (NMO) Schilder's Disease Transverse Myelitis d Symptoms & Diagnosis d Diagnosing MS d ... Overview (.pdf) Download Document Pediatric MS Learn More Transverse Myelitis Learn More Neuromyelitis Optica (NMO) Learn More ...

Relapsing-Remitting MS (RRMS)

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Adaptability-what it is and what it is not: Comment on Chandra and Leong (2016).

Science.gov (United States)

Martin, Andrew J

2017-10-01

Chandra and Leong (2016) propose a new model of adaptability: the diversified portfolio model (DPM) of adaptability. Further thought and research on adaptability is a welcome addition to the limited body of work conducted on this topic to date. However, in their discussion there is a lack of definitional clarity, and there is frequent conflation of adaptability and resilience. It is also the case that the hypothesized adaptability model is general and could apply to many psychological constructs and processes (not just adaptability). In addition, there are gaps in research suggested by the authors that have been addressed by other researchers and there is a good deal of contemporary adaptability research that is not cited. Addressing these limitations in future work is vital to the further development of theory, research, and practice in the area of adaptability. (PsycINFO Database Record (c) 2017 APA, all rights reserved).

A novel study of screening and confirmation of modafinil, adrafinil and their metabolite modafinilic acid under EI-GC-MS and ESI-LC-MS-MS ionization.

Science.gov (United States)

Dubey, S; Ahi, S; Reddy, I M; Kaur, T; Beotra, A; Jain, S

2009-12-01

Adrafinil and modafinil have received wide publicity and have become controversial in the sporting world when several athletes were discovered allegedly using these drugs as doping agents. By acknowledging the facts, the World Anti-Doping Agency (WADA) banned these drugs in sports since 2004. The present study explores the possibility of differentiating adrafinil and modafinil and their major metabolites under electron impact ionization in gas chromatograph-mass spectrometer (GC-MSD) and electrospray ionization in liquid chromatograph-mass spectrometer (LC-MS/MS) by studying the fragmentation pattern of these drugs. Adrafinil, modafinil and their major metabolite, modafinilic acid were analyzed on EI-GC-MSD and ESI-LC-MS/MS using various individual parameters on both the instruments. The analytical technique and equipment used in the analysis were an Agilent 6890N GC with 5973 mass selective detector for the GC-MSD analysis and an Agilent 1100 HPLC with API-3200 Triple quadrupole mass spectrometer for the LC-MS/MS analysis. Validation of both methods was performed using six replicates at different concentrations. The results show that adrafinil, modafinil and their major metabolite modafinilic acid could be detected as a single artifact without differentiation under EI-GC-MSD analysis. However, all drugs could be detected and differentiated under ESI-LCMS/MS analysis without any artifaction. The GC-MSD analysis gives a single artifact for both the drugs without differentiation and thus can be used as a marker for screening purposes. Further, the Multiple Reaction Monitoring (MRM) method developed under LC-MS/MS is fit for the purpose for confirmation of suspicious samples in routine sports testing and in forensic and clinical analysis.

The APEX Quantitative Proteomics Tool: Generating protein quantitation estimates from LC-MS/MS proteomics results

Directory of Open Access Journals (Sweden)

Saeed Alexander I

2008-12-01

Full Text Available Abstract Background Mass spectrometry (MS based label-free protein quantitation has mainly focused on analysis of ion peak heights and peptide spectral counts. Most analyses of tandem mass spectrometry (MS/MS data begin with an enzymatic digestion of a complex protein mixture to generate smaller peptides that can be separated and identified by an MS/MS instrument. Peptide spectral counting techniques attempt to quantify protein abundance by counting the number of detected tryptic peptides and their corresponding MS spectra. However, spectral counting is confounded by the fact that peptide physicochemical properties severely affect MS detection resulting in each peptide having a different detection probability. Lu et al. (2007 described a modified spectral counting technique, Absolute Protein Expression (APEX, which improves on basic spectral counting methods by including a correction factor for each protein (called Oi value that accounts for variable peptide detection by MS techniques. The technique uses machine learning classification to derive peptide detection probabilities that are used to predict the number of tryptic peptides expected to be detected for one molecule of a particular protein (Oi. This predicted spectral count is compared to the protein's observed MS total spectral count during APEX computation of protein abundances. Results The APEX Quantitative Proteomics Tool, introduced here, is a free open source Java application that supports the APEX protein quantitation technique. The APEX tool uses data from standard tandem mass spectrometry proteomics experiments and provides computational support for APEX protein abundance quantitation through a set of graphical user interfaces that partition thparameter controls for the various processing tasks. The tool also provides a Z-score analysis for identification of significant differential protein expression, a utility to assess APEX classifier performance via cross validation, and a

Human herpesviruses and MS

DEFF Research Database (Denmark)

Christensen, Tove

2007-01-01

and they are capable of reactivation. Epstein Barr virus (EBV), HHV-6A and varicella zoster virus (VZV) are consistently linked with MS, particularly with respect to epidemiology, antibody responses in serum (EBV) and cerebrospinal fluid (EBV and HHV-6A), and with MS exacerbations that are associated with viral...... reactivation (VZV, HHV-6A and EBV). HHV have the potential for a causal role in MS--they may be key players in the disease process--and this role could be mediated through several direct or indirect mechanisms....

Relapsing-Remitting MS (RRMS)

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Full Text Available ... working effectively. How does RRMS differ from progressive types of MS? While RRMS is defined by attacks of ... forms of MS involve much less of this type of inflammation. People with RRMS tend to have more ...

Relapsing-Remitting MS (RRMS)

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Full Text Available ... More Schilder's Disease Learn More The National MS Society is Here to Help Need More Information? We ... Twitter LinkedIn YouTube Pinterest MS Connection About the Society Vision Careers Leadership Cultural Values Financials News Press ...

Quantification of free and total sialic acid excretion by LC-MS/MS

NARCIS (Netherlands)

van der Ham, Maria; Prinsen, Berthil H. C. M. T.; Huijmans, Jan G. M.; Abeling, Nicolaas G. G. M.; Dorland, Bert; Berger, Ruud; de Koning, Tom J.; de Sain-van der Velden, Monique G. M.

2007-01-01

The main purpose for measuring urinary free sialic acid (FSA) is to diagnose sialic acid (SA) storage diseases. Elevated amounts of conjugated sialic acid (CSA) are observed in several diseases indicating the need to quantify CSA as well. A LC-MS/MS method for quantification of FSA and total sialic

ms_lims, a simple yet powerful open source laboratory information management system for MS-driven proteomics.

Science.gov (United States)

Helsens, Kenny; Colaert, Niklaas; Barsnes, Harald; Muth, Thilo; Flikka, Kristian; Staes, An; Timmerman, Evy; Wortelkamp, Steffi; Sickmann, Albert; Vandekerckhove, Joël; Gevaert, Kris; Martens, Lennart

2010-03-01

MS-based proteomics produces large amounts of mass spectra that require processing, identification and possibly quantification before interpretation can be undertaken. High-throughput studies require automation of these various steps, and management of the data in association with the results obtained. We here present ms_lims (http://genesis.UGent.be/ms_lims), a freely available, open-source system based on a central database to automate data management and processing in MS-driven proteomics analyses.

Middle school students' understanding of the natural history of the Earth and life on Earth as a function of deep time

Science.gov (United States)

Pulling, Azalie Cecile

The purpose of this study was to use deep time, that is geologic time as a mechanism to explore middle school students' understanding of the natural history of the earth and the evolution of life on earth. Geologic time is a logical precursor to middle school students' understanding of biological evolution. This exploratory, mixed model study used qualitative and quantitative methods in each stage of the research to explore sixth grade students, understanding of geologic time, their worldviews (e.g., conceptual ecology), and conceptual change. The study included fifty-nine students in the large group study and four case studies. The primary data collection instrument was the Geologic Timeline Survey. Additional data collection instruments and methods (e.g., concept evaluation statement, journal entries, word associations, interviews, and formal tests) were used to triangulate the study findings. These data were used to create narrative modal profiles of the categories of student thinking that emerged from the large group analysis: Middle School (MS) Scientists (correct science), MS Protoscientists (approaching correct science), MS Prescientists (dinosaur understanding), and MS Pseudoscientists (fundamental religious understanding). Case studies were used to provide a thick description of each category. This study discovered a pattern of student thinking about geologic time that moved along a knowledge continuum from pseudoscience (fundamental creationist understanding) to prescience (everyday-science understanding) to science (correct or approaching correct science). The researcher described the deep-seated misconceptions produced by the prescience thinking level, e.g., dinosaur misconceptions, and cautioned the science education community about using dinosaurs as a glamour-science topic. The most limiting conceptual frameworks found in this study were prescience (a dinosaur focus) and pseudoscience (a fundamental religious focus). An understanding of geologic time

Deep Vs Profiling Along the Top of Yucca Mountain Using a Vibroseis Source and Surface Waves

International Nuclear Information System (INIS)

Stokoe, K.; Rosenblad, B.; Wong, I.; Bay, J.; Thomas, P.; Silva, W.

2004-01-01

Yucca Mountain, Nevada, was approved as the site for development of the geologic repository for high-level radioactive waste and spent nuclear fuel in the United States. The U.S. Department of Energy has been conducting studies to characterize the site and assess its future performance as a geologic repository. As part of these studies, a program of deep seismic profiling, to depths of 200 m, was conducted along the top of Yucca Mountain to evaluate the shear-wave velocity (V s ) structure of the repository block. The resulting V s data were used as input into the development of ground motions for the preclosure seismic design of the repository and for postclosure performance assessment. The noninvasive spectral-analysis-of-surface-waves (SASW) method was employed in the deep profiling. Field measurements involved the use of a modified Vibroseis as the seismic source. The modifications allowed the Vibroseis to be controlled by a signal analyzer so that slow frequency sweeps could be performed while simultaneous narrow-band filtering was performed on the receiver outputs. This process optimized input energy from the source and signal analysis of the receiver outputs. Six deep V s profiles and five intermediate-depth (about 100 m) profiles were performed along the top of Yucca Mountain over a distance of about 5 km. In addition, eleven shallower profiles (averaging about 45-m deep) were measured using a bulldozer source. The shallower profiles were used to augment the deeper profiles and to evaluate further the near-surface velocity structure. The V s profiles exhibit a strong velocity gradient within 5 m of the surface, with the mean V s value more than doubling. Below this depth, V s gradually increases from a mean value of about 900 to 1000 m/s at a depth of 150 m. Between the depths of 150 and 210 m, V s increases more rapidly to about 1350 m/s, but this trend is based on limited data. At depths less than 50 m, anisotropy in V s was measured for surveys conducted

HDE 245059: A WEAK-LINED T TAURI BINARY REVEALED BY CHANDRA AND KECK

International Nuclear Information System (INIS)

Baldovin-Saavedra, C.; Audard, M.; Duchene, G.; Guedel, M.; Skinner, S.L.; Paerels, F. B. S.; Ghez, A.; McCabe, C.

2009-01-01

We present the Chandra High Energy Transmission Grating Spectrometer and Keck observations of HDE 245059, a young weak-lined T Tauri star (WTTS), member of the pre-main-sequence group in the λ Orionis Cluster. Our high spatial resolution, near-infrared observations with Keck reveal that HDE 245059 is in fact a binary separated by 0.''87, probably composed of two WTTS based on their color indices. Based on this new information we have obtained an estimate of the masses of the binary components; ∼3 M sun and ∼2.5 M sun for the north and south components, respectively. We have also estimated the age of the system to be ∼2-3 Myr. We detect both components of the binary in the zeroth-order Chandra image and in the grating spectra. The light curves show X-ray variability of both sources and in particular a flaring event in the weaker southern component. The spectra of both stars show similar features: a combination of cool and hot plasma as demonstrated by several iron lines from Fe XVII to Fe XXV and a strong bremsstrahlung continuum at short wavelengths. We have fitted the combined grating and zeroth-order spectrum (considering the contribution of both stars) in XSPEC. The coronal abundances and emission measure distribution for the binary have been obtained using different methods, including a continuous emission measure distribution and a multi-temperature approximation. In all cases we have found that the emission is dominated by plasma between ∼8 and ∼15 MK a soft component at ∼4 MK and a hard component at ∼50 MK are also detected. The value of the hydrogen column density was low, N H ∼ 8 x 10 19 cm -2 , likely due to the clearing of the inner region of the λ Orionis cloud, where HDE 245059 is located. The abundance pattern shows an inverse first ionization potential effect for all elements from O to Fe, the only exception being Ca. To obtain the properties of the binary components, a 3-T model was fitted to the individual zeroth-order spectra

Deep learning

CERN Document Server

Goodfellow, Ian; Courville, Aaron

2016-01-01

Deep learning is a form of machine learning that enables computers to learn from experience and understand the world in terms of a hierarchy of concepts. Because the computer gathers knowledge from experience, there is no need for a human computer operator to formally specify all the knowledge that the computer needs. The hierarchy of concepts allows the computer to learn complicated concepts by building them out of simpler ones; a graph of these hierarchies would be many layers deep. This book introduces a broad range of topics in deep learning. The text offers mathematical and conceptual background, covering relevant concepts in linear algebra, probability theory and information theory, numerical computation, and machine learning. It describes deep learning techniques used by practitioners in industry, including deep feedforward networks, regularization, optimization algorithms, convolutional networks, sequence modeling, and practical methodology; and it surveys such applications as natural language proces...

Extreme diving behaviour in devil rays links surface waters and the deep ocean

KAUST Repository

Thorrold, Simon R.

2014-07-01

Ecological connections between surface waters and the deep ocean remain poorly studied despite the high biomass of fishes and squids residing at depths beyond the euphotic zone. These animals likely support pelagic food webs containing a suite of predators that include commercially important fishes and marine mammals. Here we deploy pop-up satellite archival transmitting tags on 15 Chilean devil rays (Mobula tarapacana) in the central North Atlantic Ocean, which provide movement patterns of individuals for up to 9 months. Devil rays were considered surface dwellers but our data reveal individuals descending at speeds up to 6.0 ms-1 to depths of almost 2,000 m and water temperatures <4 C. The shape of the dive profiles suggests that the rays are foraging at these depths in deep scattering layers. Our results provide evidence of an important link between predators in the surface ocean and forage species occupying pelagic habitats below the euphotic zone in ocean ecosystems. 2014 Macmillan Publishers Limited. All rights reserved.

Diet-induced perturbation of the rat liver mitochondrial acetylome studied by quantitative (iTRAQ) LC-MS/MS

DEFF Research Database (Denmark)

León, Ileana R.; Schwämmle, Veit; Williamson, James

described3. Quantitation by MS/MS was achieved by using iTRAQ 8-Plex reagents (Life Technologies). LC-MS/MS analyses were performed using an Easy-nLC (Proxeon/ThermoFisher) fitted with an in-house made 17 cm C18 column that was interfaced to an LTQ-OrbiTrap XL instrument (ThermoFisher). Data analysis...

Relapsing-Remitting MS (RRMS)

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Full Text Available ... Review of Society's Research Programs d Careers d Leadership Board of Directors Senior Leadership Team Founder Sylvia Lawry d Cultural Values d ... Pinterest MS Connection About the Society Vision Careers Leadership Cultural Values Financials News Press Room MS Prevalence ...

Relapsing-Remitting MS (RRMS)

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Full Text Available ... Another Condition Aging with MS Anesthesia and Surgery Managing Your MS d Emotional Well-Being Mood Changes d Spiritual Well-Being Building Spirituality into Your Life d Cognitive Health d Work, Home & Leisure Employment Insurance & Financial Information Staying Mobile ...

Comprehensive analysis of proteins of pH fractionated samples using monolithic LC/MS/MS, intact MW measurement and MALDI-QIT-TOF MS

Science.gov (United States)

Yoo, Chul; Patwa, Tasneem H.; Kreunin, Paweena; Miller, Fred R.; Huber, Christian G.; Nesvizhskii, Alexey I.; Lubman, David M.

2012-01-01

A comprehensive platform that integrates information from the protein and peptide levels by combining various MS techniques has been employed for the analysis of proteins in fully malignant human breast cancer cells. The cell lysates were subjected to chromatofocusing fractionation, followed by tryptic digestion of pH fractions for on-line monolithic RP-HPLC interfaced with linear ion trap MS analysis for rapid protein identification. This unique approach of direct analysis of pH fractions resulted in the identification of large numbers of proteins from several selected pH fractions, in which approximately 1.5 μg of each of the pH fraction digests was consumed for an analysis time of ca 50 min. In order to combine valuable information retained at the protein level with the protein identifications obtained from the peptide level information, the same pH fraction was analyzed using nonporous (NPS)-RP-HPLC/ESI-TOF MS to obtain intact protein MW measurements. In order to further validate the protein identification procedures from the fraction digest analysis, NPS-RP-HPLC separation was performed for off-line protein collection to closely examine each protein using MALDI-TOF MS and MALDI-quadrupole ion trap (QIT)-TOF MS, and excellent agreement of protein identifications was consistently observed. It was also observed that the comparison to intact MW and other MS information was particularly useful for analyzing proteins whose identifications were suggested by one sequenced peptide from fraction digest analysis. PMID:17206599

Quantification of acetaminophen (paracetamol) in human plasma and urine by stable isotope-dilution GC-MS and GC-MS/MS as pentafluorobenzyl ether derivative.

Science.gov (United States)

Trettin, Arne; Zoerner, Alexander A; Böhmer, Anke; Gutzki, Frank-Mathias; Stichtenoth, Dirk O; Jordan, Jens; Tsikas, Dimitrios

2011-08-01

We report on the quantitative determination of acetaminophen (paracetamol; NAPAP-d(0)) in human plasma and urine by GC-MS and GC-MS/MS in the electron-capture negative-ion chemical ionization (ECNICI) mode after derivatization with pentafluorobenzyl (PFB) bromide (PFB-Br). Commercially available tetradeuterated acetaminophen (NAPAP-d(4)) was used as the internal standard. NAPAP-d(0) and NAPAP-d(4) were extracted from 100-μL aliquots of plasma and urine with 300 μL ethyl acetate (EA) by vortexing (60s). After centrifugation the EA phase was collected, the solvent was removed under a stream of nitrogen gas, and the residue was reconstituted in acetonitrile (MeCN, 100 μL). PFB-Br (10 μL, 30 vol% in MeCN) and N,N-diisopropylethylamine (10 μL) were added and the mixture was incubated for 60 min at 30 °C. Then, solvents and reagents were removed under nitrogen and the residue was taken up with 1000 μL of toluene, from which 1-μL aliquots were injected in the splitless mode. GC-MS quantification was performed by selected-ion monitoring ions due to [M-PFB](-) and [M-PFB-H](-), m/z 150 and m/z 149 for NAPAP-d(0) and m/z 154 and m/z 153 for NAPAP-d(4), respectively. GC-MS/MS quantification was performed by selected-reaction monitoring the transition m/z 150 → m/z 107 and m/z 149 → m/z 134 for NAPAP-d(0) and m/z 154 → m/z 111 and m/z 153 → m/z 138 for NAPAP-d(4). The method was validated for human plasma (range, 0-130 μM NAPAP-d(0)) and urine (range, 0-1300 μM NAPAP-d(0)). Accuracy (recovery, %) ranged between 89 and 119%, and imprecision (RSD, %) was below 19% in these matrices and ranges. A close correlation (r>0.999) was found between the concentrations measured by GC-MS and GC-MS/MS. By this method, acetaminophen can be reliably quantified in small plasma and urine sample volumes (e.g., 10 μL). The analytical performance of the method makes it especially useful in pediatrics. Copyright © 2011 Elsevier B.V. All rights reserved.

VOC identification and inter-comparison from laboratory biomass burning using PTR-MS and PIT-MS

Science.gov (United States)

C. Warneke; J. M. Roberts; P. Veres; J. Gilman; W. C. Kuster; I. Burling; R. Yokelson; J. A. de Gouw

2011-01-01

Volatile organic compounds (VOCs) emitted from fires of biomass commonly found in the southeast and southwest U.S. were investigated with PTR-MS and PIT-MS, which are capable of fast measurements of a large number of VOCs. Both instruments were calibrated with gas standards and mass dependent calibration curves are determined. The sensitivity of the PIT-MS linearly...

Living with a Red Dwarf: A Chandra Archival Study of dM Star Activity and Habitability

Science.gov (United States)

Engle, Scott

2017-09-01

We propose to analyze 6 archival Chandra visits, not pointed at, but serendipitously including 3 dM stars of known age. GJ 669 AB are a common proper motion pair, each are resolved and detected in 3 exposures, and LHS 373 is a much older dM star also detected on 3 exposures. Photometry (by us) of GJ 669 AB began 5 years ago, is ongoing, and has precisely determined rotation rates for both stars and evidence of frequent flaring from GJ 669 B. We will analyze the multiple exposures, derive an accurate mean level of X-ray activity from the targets, and also separate out and individually analyze and model any observed X-ray flares. This proposal will provide highly accurate coronal properties for the targets, but also very useful data for stellar evolution and planetary habitability studies.

HPLC-UV, MALDI-TOF-MS and ESI-MS/MS analysis of the mechlorethamine DNA crosslink at a cytosine-cytosine mismatch pair.

Directory of Open Access Journals (Sweden)

Pornchai Rojsitthisak

Full Text Available Mechlorethamine [ClCH(2CH(2N(CH(3CH(2CH(2Cl], a nitrogen mustard alkylating agent, has been proven to form a DNA interstrand crosslink at a cytosine-cytosine (C-C mismatch pair using gel electrophoresis. However, the atomic connectivity of this unusual crosslink is unknown.HPLC-UV, MALDI-TOF-MS, and ESI-MS/MS were used to determine the atomic connectivity of the DNA C-C crosslink formed by mechlorethamine, MALDI-TOF-MS of the HPLC-purified reaction product of mechlorethamine with the DNA duplex d[CTCACACCGTGGTTC]•d[GAACCACCGTGTGAG] (underlined bases are a C-C mismatch pair indicated formation of an interstrand crosslink at m/z 9222.088 [M-2H+Na](+. Following enzymatic digestion of the crosslinked duplex by snake venom phosphodiesterase and calf intestinal phosphatase, ESI-MS/MS indicated the presence of dC-mech-dC [mech = CH(2CH(2N(CH(3CH(2CH(2] at m/z 269.2 [M](2+ (expected m/z 269.6, exact mass 539.27 and its hydrolytic product dC-mech-OH at m/z 329.6 [M](+ (expected m/z 329.2. Fragmentation of dC-mech-dC gave product ions at m/z 294.3 and 236.9 [M](+, which are both due to loss of the 4-amino group of cytosine (as ammonia, in addition to dC and dC+HN(CH(3CH = CH(2, respectively. The presence of m/z 269.2 [M](2+ and loss of ammonia exclude crosslink formation at cytosine N(4 or O(2 and indicate crosslinking through cytosine N(3 with formation of two quaternary ammonium ions.Our results provide an important addition to the literature, as the first example of the use of HPLC and MS for analysis of a DNA adduct at the N(3 position of cytosine.