WorldWideScience

Sample records for monthly safety bulletin

  1. Safety Bulletin 2014-2

    CERN Multimedia

    HSE Unit

    2014-01-01

    The HSE Unit would like to inform you that the Safety Bulletin 2014-2 entitled “False floors: real dangers” has just been released.     The Bulletin is available on EDMS under the following number: 1366385. We would like to remind you that HSE Safety Bulletins are published in English and French and incorporate feedback from incidents/near misses/accidents that have occurred on the CERN site, with the aim of improving prevention. We remain at your disposal in case you have further questions: safety.bulletin@cern.ch.

  2. Safety Bulletin 2013-4

    CERN Multimedia

    HSE Unit

    2013-01-01

    The HSE Unit has just released the Safety Bulletin 2013-4 entitled “Electrical work: protect yourself!”.   The Bulletin is available on EDMS under the following number: 1336918. We would like to remind you that HSE Safety Bulletins are published in English and French and share feedback from incidents/near misses/accidents that have occurred on the CERN site with the aim of improving prevention.

  3. Safety Bulletin 2013-3

    CERN Multimedia

    HSE Unit

    2013-01-01

    The HSE Unit just released the Safety Bulletin 2013-3 entitled “Drive with caution!”.   The Bulletin is available on EDMS under the following number: 1325442. Be reminded  that HSE Safety Bulletins are published in English and French and share feedbacks of incidents/nearmiss/accidents that happened on the CERN site with the aim to improve prevention.

  4. Safety Bulletin 2013-1

    CERN Multimedia

    HSE Unit

    2013-01-01

    The HSE Unit has just released the Safety Bulletin 2013-1 entitled “When the alarm rings, you must leave!”.   The Bulletin is available on EDMS under the following number: 1307611. Be reminded  that HSE Safety Bulletins are published in English and French and share feedback on incidents/nearmiss/accidents on the CERN site with the aim of improving prevention.

  5. Safety Bulletin 2013-2

    CERN Multimedia

    HSE Unit

    2013-01-01

    The HSE Unit just released the Safety Bulletin 2013-2 entitled “Protect your head!”.   The Bulletin is available on EDMS under the following number: 1323573. We would like to remind you that HSE Safety Bulletins are published in English and French and share feedback from incidents/near misses/accidents that have occurred on the CERN site with the aim of improving prevention.

  6. Safety Bulletin 2014-1

    CERN Multimedia

    HSE Unit

    2014-01-01

    The HSE Unit would like to inform you that Safety Bulletin 2014-1 entitled “Call for help!” has just been released.   The Bulletin is available on EDMS under the following number: 1346313. We would like to remind you that HSE Safety Bulletins are published in English and French, and incorporate feedback from incidents/near misses/accidents that have occurred on the CERN site with the aim of improving prevention. We remain at your disposal in case you have further questions.

  7. Monthly bulletin of statistics. May 1995

    International Nuclear Information System (INIS)

    1995-01-01

    The purpose of this publication is to present current monthly economic statistics for most of the countries and territories of the world. In addition, each month a different selection of special tables is presented showing annual and/or quarterly data on a variety of subjects illustrating important economic long-term trends and developments. Most of these special tables are also reproduced in the United Nations Statistical Yearbook. It is, however, considered to be useful to publish these data in the Bulletin as soon as they become available so that readers may have immediate access to the most current international statistical information

  8. Monthly bulletin of statistics. January 1996

    International Nuclear Information System (INIS)

    1996-01-01

    The purpose of this publication is to present current monthly economic statistics for most of the countries and territories of the world. In addition, each month a different selection of special tables is presented showing annual and/or quarterly data on a variety of subjects illustrating important economic long-term trends and developments. Most of these special tables are also reproduced in the United Nations Statistical Yearbook. It is, however, considered to be useful to publish these data in the Bulletin as soon as they become available so that readers may have immediate access to the most current international statistical information

  9. Monthly bulletin of statistics. July 1997

    International Nuclear Information System (INIS)

    1997-01-01

    The purpose of this publication is to present current monthly economic statistics for most of the countries and territories of the world. In addition, each month a different selection of special tables is presented showing annual and/or quarterly data on a variety of subjects illustrating important economic long-term trends and developments. Most of these special tables are also reproduced in the United Nations Statistical Yearbook. It is, however, considered to be useful to publish these data in the Bulletin as soon as they become available so that readers may have immediate access to the most current international statistical information

  10. Monthly bulletin of statistics. June 2001

    International Nuclear Information System (INIS)

    2001-01-01

    The purpose of this publication is to present current monthly economic statistics for most of the countries and territories of the world. In addition, each month a different selection of special tables is presented showing annual and/or quarterly data on a variety of subjects illustrating important economic long-term trends and developments. Most of these special tables are also reproduced in the United Nations Statistical Yearbook. It is, however, considered to be useful to publish these data in the Bulletin as soon as they become available so that readers may have immediate access to the most current international statistical information

  11. Monthly bulletin of statistics. September 1995

    International Nuclear Information System (INIS)

    1995-01-01

    The purpose of this publication is to present current monthly economic statistics for most of the countries and territories of the world. In addition, each month a different selection of special tables is presented showing annual and/or quarterly data on a variety of subjects illustrating important economic long-term trends and developments. Most of these special tables are also reproduced in the United Nations Statistical Yearbook. It is, however, considered to be useful to publish these data in the Bulletin as soon as they become available so that readers may have immediate access to the most current international statistical information

  12. Monthly bulletin of statistics. December 1994

    International Nuclear Information System (INIS)

    1994-01-01

    The purpose of this publication is to present current monthly economic statistics for most of the countries and territories of the world. In addition, each month a different selection of special tables is presented showing annual and/or quarterly data on a variety of subjects illustrating important economic long-term trends and developments. Most of these special tables are also reproduced in the United Nations Statistical Yearbook. It is, however, considered to be useful to publish these data in the Bulletin as soon as they become available so that readers may have immediate access to the most current international statistical information

  13. Monthly bulletin of statistics. July 1995

    International Nuclear Information System (INIS)

    1995-01-01

    The purpose of this publication is to present current monthly economic statistics for most of the countries and territories of the world. In addition, each month a different selection of special tables is presented showing annual and/or quarterly data on a variety of subjects illustrating important economic long-term trends and developments. Most of these special tables are also reproduced in the United Nations Statistical Yearbook. It is, however, considered to be useful to publish these data in the Bulletin as soon as they become available so that readers may have immediate access to the most current international statistical information

  14. Monthly bulletin of statistics. September 1994

    International Nuclear Information System (INIS)

    1994-01-01

    The purpose of this publication is to present current monthly economic statistics for most of the countries and territories of the world. In addition, each month a different selection of special tables is presented showing annual and/or quarterly data on a variety of subjects illustrating important economic long-term trends and developments. Most of these special tables are also reproduced in the United Nations Statistical Yearbook. It is, however, considered to be useful to publish these data in the Bulletin as soon as they become available so that readers may have immediate access to the most current international statistical information

  15. Monthly bulletin of statistics. March 1995

    International Nuclear Information System (INIS)

    1994-01-01

    The purpose of this publication is to present current monthly economic statistics for most of the countries and territories of the world. In addition, each month a different selection of special tables is presented showing annual and/or quarterly data on a variety of subjects illustrating important economic long-term trends and developments. Most of these special tables are also reproduced in the United Nations Statistical Yearbook. It is, however, considered to be useful to publish these data in the Bulletin as soon as they become available so that readers may have immediate access to the most current international statistical information

  16. Monthly bulletin of statistics. October 2007

    International Nuclear Information System (INIS)

    2007-01-01

    The purpose of this publication is to present current monthly economic statistics for most of the countries and territories of the world. In addition, each month a different selection of special tables is presented showing annual and/or quarterly data on a variety of subjects illustrating important economic long-term trends and developments. Most of these special tables are also reproduced in the United Nations Statistical Yearbook. It is, however, considered to be useful to publish these data in the Bulletin as soon as they become available so that readers may have immediate access to the most current international statistical information

  17. Monthly bulletin of statistics. October 1993

    International Nuclear Information System (INIS)

    1993-01-01

    The purpose of this publication is to present current monthly economic statistics for most of the countries and territories of the world. In addition, each month a different selection of special tables is presented showing annual and/or quarterly data on a variety of subjects illustrating important economic long-term trends and developments. Most of these special tables are also reproduced in the United Nations Statistical Yearbook. It is, however, considered to be useful to publish these data in the Bulletin as soon as they become available so that readers may have immediate access to the most current international statistical information

  18. Monthly Bulletin of Statistics. July 1993

    International Nuclear Information System (INIS)

    1993-01-01

    The purpose of this publication is to present current monthly economic statistics for most of the countries and territories of the world. In addition, each month a different selection of special tables is presented showing annual and/or quarterly data on a variety of subjects illustrating important economic long-term trends and developments. Most of these special tables are also reproduced in the United Nations Statistical Yearbook. It is, however, considered to be useful to publish these data in the Bulletin as soon as they become available so that readers may have immediate access to the most current international statistical information

  19. Monthly bulletin of statistics. March 1994

    International Nuclear Information System (INIS)

    1994-01-01

    The purpose of this publication is to present current monthly economic statistics for most of the countries and territories of the world. In addition, each month a different selection of special tables is presented showing annual and/or quarterly data on a variety of subjects illustrating important economic long-term trends and developments. Most of these special tables are also reproduced in the United Nations Statistical Yearbook. It is, however, considered to be useful to publish these data in the Bulletin as soon as they become available so that readers may have immediate access to the most current international statistical information

  20. Monthly bulletin of statistics. February 1994

    International Nuclear Information System (INIS)

    1994-01-01

    The purpose of this publication is to present current monthly economic statistics for most of the countries and territories of the world. In addition, each month a different selection of special tables is presented showing annual and/or quarterly data on a variety of subjects illustrating important economic long-term trends and developments. Most of these special tables are also reproduced in the United Nations Statistical Yearbook. It is, however, considered to be useful to publish these data in the Bulletin as soon as they become available so that readers may have immediate access to the most current international statistical information

  1. Monthly bulletin of statistics. June 1995

    International Nuclear Information System (INIS)

    1995-01-01

    The purpose of this publication is to present current monthly economic statistics for most of the countries and territories of the world. In addition, each month a different selection of special tables is presented showing annual and/or quarterly data on a variety of subjects illustrating important economic long-term trends and developments. Most of these special tables are also reproduced in the United Nations Statistical Yearbook. It is, however, considered to be useful to publish these data in the Bulletin as soon as they become available so that readers may have immediate access to the most current international statistical information

  2. Monthly bulletin of statistics. November 2008

    International Nuclear Information System (INIS)

    2008-01-01

    The purpose of this publication is to present current monthly economic statistics for most of the countries and territories of the world. In addition, each month a different selection of special tables is presented showing annual and/or quarterly data on a variety of subjects illustrating important economic long-term trends and developments. Most of these special tables are also reproduced in the United Nations Statistical Yearbook. It is, however, considered to be useful to publish these data in the Bulletin as soon as they become available so that readers may have immediate access to the most current international statistical information

  3. Monthly bulletin of electric power market - November 1988

    International Nuclear Information System (INIS)

    1988-01-01

    This bulletin deals with the brazilian electric power consumption in November 1988, containing data about the total consumption, the growth rates, the special tariffs and monthly evolution in each brazilian region. The economic indexes of industrial production, the market and the prices of electric power and petroleum products are also presented. (C.G.C.)

  4. Monthly bulletin of electric power market - July 1988

    International Nuclear Information System (INIS)

    1988-01-01

    This bulletin deals with the brazilian electric power consumption in July 1988, containing data about the total consumption, the growth rates, the special tariffs and monthly evolution in each brazilian region. The economic indexes of industrial production, the market and the prices of electric power and petroleum products are also presented. (C.G.C.)

  5. Monthly bulletin of electric power market - September 1988

    International Nuclear Information System (INIS)

    1988-01-01

    This bulletin deals with the brazilian electric power consumption in September 1988, containing data about the total consumption, the growth rates, the special tariffs and monthly evolution in each brazilian region. The economic indexes of industrial production, the market and the prices of electric power and petroleum products are also presented. (C.G.C.)

  6. Public safety around dams : proposed technical bulletins

    Energy Technology Data Exchange (ETDEWEB)

    Raska, C [BC Hydro, Burnaby, BC (Canada); Rowat, L [Ontario Power Generation Inc., Niagara Falls, ON (Canada)

    2009-07-01

    This presentation provided an introduction to the Canadian Dam Association (CDA) public safety guideline and proposed technical bulletins for exterior danger and warning signs; waterway booms and buoys; and audible and visual alerts for water conveyance structures. The presentation outlined the hierarchy of documents for principles, guidelines and technical bulletins. Effective signage includes signs in which the text is sized according to the viewing distance; the message identifies the hazard and the actions to take; and the wording is understood by the public. The criteria for effective booms and buoys were discussed in terms of visibility of booms; types of buoys to use; distance between booms floats; design issues for headpond application versus tailrace application; angling to facilitate self-rescue; and distance from structure. Proposed criteria for audible and visual alerts were also discussed. The audible and visual danger signal should have a designated signal reception area where people can recognize and react to the signal. If a visual signalling device is used, it should be red to indicate danger. Maintenance and inspection tests should be performed regularly on audible and visual signalling devices. 1 ref., 2 figs.

  7. Technical bulletin : structural considerations for dam safety

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2007-07-01

    This technical bulletin discussed issues related to the safety assessment of concrete water-retaining structures and timber dams. Structures reviewed in the paper included gravity dams; buttress dams; arch dams; spillway structures; intake structures; power plants; roller compacted concrete dams; and timber dams. A variety of issues related to the loss of cohesive bond and discontinuities in bedrock foundations were reviewed with reference to issues related to compressive strength, tensile strength, and shear strength. Static failure modes and failure mechanisms related to dam failures were also described. Visual indicators for potential failures include abutment and foundation movement, seepage, and structure movements. Loading combinations were discussed, and performance indicators for gravity dams were provided. Methods of analysis for considering load characteristics, structure types and geological conditions were also discussed. Modelling techniques for finite element analysis were also included. 16 refs., 3 tabs., 5 figs.

  8. Safety Bulletin 2013-1: When the alarm rings, you must leave!

    CERN Multimedia

    HSE Unit

    2013-01-01

    The HSE Unit just released the Safety Bulletin 2013-1 entitled “When the alarm rings, you must leave!”. The Bulletin is available on EDMS under the following number: 1307611. Be reminded  that HSE Safety Bulletins are published in English and French and share feedbacks of incidents/near miss/accidents that happened on the CERN site with the aim to improve prevention.

  9. Motorcycle Safety Education. Bulletin No. 21.

    Science.gov (United States)

    Alabama State Dept. of Education, Montgomery. Div. of Instructional Services.

    This guide for motorcycle safety instructors is intended to provide essential information in a usable format for teaching the basic knowledge and skills to (1) maintain the motorcycle in a safe riding condition; (2) develop an ability to handle the motorcycle in a safe and sane manner; (3) develop defensive driving techniques; and (4) understand…

  10. O.P.R.I. Monthly Bulletin. August 1998

    International Nuclear Information System (INIS)

    1998-08-01

    The OPRI Monthly Report, August 1998 Issue, reports the measurement results concerning activity levels obtained from atmospheric sampling (air at ground and high-altitude level and the atmospheric tritium concentration at VALDUC), from rain water, ground, underground and sea waters. Also, radioactivity levels are given for drinking water, food chains (particularly in cow milk and fish available on national market) and vegetables. Data resulted from radiation surveillance of industrial nuclear facilities and waste waters from non-industrial units like hospitals and research institutions are also given. The report presents the system of environmental gamma radiation monitoring based on the TELERAY Network consisting of 174 stations throughout French territory as well as the medical control for professionals and the radioactivity control following radiation incidents

  11. Laboratory Safety Manual for Alabama Schools. Bulletin 1975. No. 20.

    Science.gov (United States)

    Alabama State Dept. of Education, Montgomery.

    This document presents the Alabama State Department of Education guidelines for science laboratory safety, equipment, storage, chemical safety, rocket safety, electrical safety, safety with radioisotopes, and safety with biologicals. Also included is a brief bibliography, a teacher's checklist, a listing of laser facts and regulations, and a…

  12. IDRC Bulletin — March 2017

    International Development Research Centre (IDRC) Digital Library (Canada)

    IDRC Bulletin — March 2017. Featured this month. Nighat Dad. Protecting digital rights in Pakistan. Nighat Dad is winning global accolades for her quest to protect women's safety on the Internet, while urging governments to balance cyber security with citizen rights. Find out how. News. Research for a climate-smart world.

  13. SAFETY BULLETIN TIS 2002-03 GLASS DOORS

    CERN Multimedia

    2002-01-01

    Be careful! What happened?   Unsignaled reinforced glass.   Signaled safety glass.   A visitor recently hurt his leg when he walked into a glass door which shattered from the impact. This door was made of reinforced glass, a material which is inappropriate for this kind of use as it is too fragile. Indeed, it shatters into sharp splinters which can cause serious injury. Furthermore, the door was not easily visible (badly lit, no warning signs, ...). Corrective measures Just after the accident: glass doors were signed to make them more visible; replacement of dangerous glass panes planned for 2003. What preventive measures can be taken against this kind of accident? If you are in charge of projects and works: In the call for tender, specify the acceptable shock resistance level of the glass pane; Before the door is mounted, insist on receiving technical documentation and/or certificate of conformity from the supplier; If in doubt, ask advice from the TIS/GS sa...

  14. Solar Indices Bulletin

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Solar Indices Bulletin is a prompt monthly information product that is distributed within two weeks after the observation month closes. For the month just ended,...

  15. O.P.R.I. Monthly Bulletin. August 1998; Tableaux mensuels des mesures. Aout 1998

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1998-08-01

    The OPRI Monthly Report, August 1998 Issue, reports the measurement results concerning activity levels obtained from atmospheric sampling (air at ground and high-altitude level and the atmospheric tritium concentration at VALDUC), from rain water, ground, underground and sea waters. Also, radioactivity levels are given for drinking water, food chains (particularly in cow milk and fish available on national market) and vegetables. Data resulted from radiation surveillance of industrial nuclear facilities and waste waters from non-industrial units like hospitals and research institutions are also given. The report presents the system of environmental gamma radiation monitoring based on the TELERAY Network consisting of 174 stations throughout French territory as well as the medical control for professionals and the radioactivity control following radiation incidents 2 figs., 64 tabs.

  16. Closeout of IE Bulletin 84-02: Failures of General Electric Type HFA relays in use in Class 1E safety systems

    International Nuclear Information System (INIS)

    Foley, W.J.; Dean, R.S.; Hennick, A.

    1991-01-01

    Documentation is provided in this report to close IE Bulletin 84--02 regarding the failure of General Electric Type HFA relays in Class 1E safety systems. The relay failures were due to aging of coil wire insulation and nylon or Lexan spools under certain environmental conditions. The bulletin was issued to nuclear power reactor licensees and holders of construction permits to provide assurance that the manufacturer's recommendations for corrective actions would be implemented. The bulletin required four specific actions, plus a review of the general concerns of the bulletin even though some facilities had different relays from those of bulletin concern. Evaluation of utility responses, NRC/Region inspection reports, and regional telephone calls has resulted in bulletin closeout of 116 (98%) of the 118 facilities to which the bulletin was issued for action. Facilities which were shut down or had construction halted indefinitely or permanently when the report was issued are not included in this review. A follow-up item is proposed in Appendix C for the two facilities with open status. Background information is supplied in the Introduction and Appendix A

  17. IDRC Bulletin #124

    International Development Research Centre (IDRC) Digital Library (Canada)

    2018-01-16

    Jan 16, 2018 ... In this issue, read the research results from our Safe and Inclusive Cities program and don't forget that the Joint Canada-Israel Health Research Program 2018 call is now open. IDRC Bulletin logo IDRC Bulletin — Winter 2017. Featured this month. View of Port-au-Prince in Haiti, March 30, 2016. Safe and ...

  18. New Bulletin: Latest News

    CERN Multimedia

    2005-01-01

    The paper version of the CERN Bulletin will be published twice a month with effect from 18 April 2005. The electronic version will be updated weekly. This year will see many changes in the Bulletin, designed to make it more economical, more compact and more attractive.

  19. 76 FR 27843 - National Building Safety Month, 2011

    Science.gov (United States)

    2011-05-13

    ... organizations and the public and private sectors--to implement effective standards and codes that sustain safe... and fire prevention codes help us withstand, mitigate, and rapidly recover from hurricanes, winter... Building Safety Month. I encourage citizens, government agencies, private businesses, nonprofit...

  20. Market bulletin - March 1989

    International Nuclear Information System (INIS)

    1989-01-01

    This bulletin deals with the brazilian electric power consumption in March 1989, containing data about the total consumption, the growth rates, the special tariffs, and the monthly evolution in each brazilian region. (C.G.C.)

  1. Market bulletin - August 1990

    International Nuclear Information System (INIS)

    1990-01-01

    This bulletin deals with the brazilian electric power consumption in August 1990, containing data about the total consumption, the growth rates, the special tariffs, and the monthly evolution in each brazilian region. (C.G.C.)

  2. Market bulletin - April 1991

    International Nuclear Information System (INIS)

    1991-01-01

    This bulletin deals with the brazilian electric power consumption in April 1991, containing data about the total consumption, the growth rates, the special tariffs, and the monthly evolution in each brazilian region. (C.G.C.)

  3. Market bulletin - December 1990

    International Nuclear Information System (INIS)

    1990-01-01

    This bulletin deals with the brazilian electric power consumption in December 1990, containing data about the total consumption, the growth rates, the special tariffs, and the monthly evolution in each brazilian region. (C.G.C.)

  4. Market bulletin - December 1989

    International Nuclear Information System (INIS)

    1989-01-01

    This bulletin deals with the brazilian electric power consumption in December 1989, containing data about the total consumption, the growth rates, the special tariffs, and the monthly evolution in each brazilian region. (C.G.C.)

  5. Market bulletin - February 1991

    International Nuclear Information System (INIS)

    1991-01-01

    This bulletin deals with the brazilian electric power consumption in February 1991, containing data about the total consumption, the growth rates, the special tariffs, and the monthly evolution in each brazilian region. (C.G.C.)

  6. Market bulletin - January 1990

    International Nuclear Information System (INIS)

    1990-01-01

    This bulletin deals with the brazilian electric power consumption in January 1990, containing data about the total consumption, the growth rates, the special tariffs, and the monthly evolution in each brazilian region. (C.G.C.)

  7. Market bulletin - September 1990

    International Nuclear Information System (INIS)

    1990-01-01

    This bulletin deals with the brazilian electric power consumption in September 1990, containing data about the total consumption, the growth rates, the special tariffs, and the monthly evolution in each brazilian region. (C.G.C.)

  8. Market bulletin - November 1990

    International Nuclear Information System (INIS)

    1990-01-01

    This bulletin deals with the brazilian electric power consumption in November 1990, containing data about the total consumption, the growth rates, the special tariffs, and the monthly evolution in each brazilian region. (C.G.C.)

  9. Market bulletin - July 1990

    International Nuclear Information System (INIS)

    1990-01-01

    This bulletin deals with the brazilian electric power consumption in July 1990, containing data about the total consumption, the growth rates, the special tariffs, and the monthly evolution in each brazilian region. (C.G.C.)

  10. Market bulletin - March 1991

    International Nuclear Information System (INIS)

    1991-01-01

    This bulletin deals with the brazilian electric power consumption in March 1991, containing data about the total consumption, the growth rates, the special tariffs, and the monthly evolution in each brazilian region. (C.G.C.)

  11. Market bulletin - September 1989

    International Nuclear Information System (INIS)

    1989-01-01

    This bulletin deals with the brazilian electric power consumption in September 1989, containing data about the total consumption, the growth rates, the special tariffs, and the monthly evolution in each brazilian region. (C.G.C.)

  12. Market bulletin - April 1989

    International Nuclear Information System (INIS)

    1989-01-01

    This bulletin deals with the brazilian electric power consumption in April 1989, containing data about the total consumption, the growth rates, the special tariffs, and the monthly evolution in each brazilian region. (C.G.C.)

  13. Market bulletin - June 1990

    International Nuclear Information System (INIS)

    1990-01-01

    This bulletin deals with the brazilian electric power consumption in June 1990, containing data about the total consumption, the growth rates, the special tariffs, and the monthly evolution in each brazilian region. (C.G.C.)

  14. Market bulletin - March 1990

    International Nuclear Information System (INIS)

    1990-01-01

    This bulletin deals with the brazilian electric power consumption in March 1990, containing data about the total consumption, the growth rates, the special tariffs, and the monthly evolution in each brazilian region. (C.G.C.)

  15. Electronic Cigarettes Efficacy and Safety at 12 Months: Cohort Study.

    Directory of Open Access Journals (Sweden)

    Lamberto Manzoli

    Full Text Available To evaluate the safety and efficacy as a tool of smoking cessation of electronic cigarettes (e-cigarettes, directly comparing users of e-cigarettes only, smokers of tobacco cigarettes only, and smokers of both.Prospective cohort study. Final results are expected in 2019, but given the urgency of data to support policies on electronic smoking, we report the results of the 12-month follow-up.Direct contact and structured questionnaires by phone or via internet.Adults (30-75 years were included if they were smokers of ≥1 tobacco cigarette/day (tobacco smokers, users of any type of e-cigarettes, inhaling ≥50 puffs weekly (e-smokers, or smokers of both tobacco and e-cigarettes (dual smokers. Carbon monoxide levels were tested in a sample of those declaring tobacco smoking abstinence.Sustained smoking abstinence from tobacco smoking at 12 months, reduction in the number of tobacco cigarettes smoked daily.We used linear and logistic regression, with region as cluster unit.Follow-up data were available for 236 e-smokers, 491 tobacco smokers, and 232 dual smokers (overall response rate 70.8%. All e-smokers were tobacco ex-smokers. At 12 months, 61.9% of the e-smokers were still abstinent from tobacco smoking; 20.6% of the tobacco smokers and 22.0% of the dual smokers achieved tobacco abstinence. Adjusting for potential confounders, tobacco smoking abstinence or cessation remained significantly more likely among e-smokers (adjusted OR 5.19; 95% CI: 3.35-8.02, whereas adding e-cigarettes to tobacco smoking did not enhance the likelihood of quitting tobacco and did not reduce tobacco cigarette consumption. E-smokers showed a minimal but significantly higher increase in self-rated health than other smokers. Non significant differences were found in self-reported serious adverse events (eleven overall.Adding e-cigarettes to tobacco smoking did not facilitate smoking cessation or reduction. If e-cigarette safety will be confirmed, however, the use of e

  16. 77 FR 17119 - Pipeline Safety: Cast Iron Pipe (Supplementary Advisory Bulletin)

    Science.gov (United States)

    2012-03-23

    ... DEPARTMENT OF TRANSPORTATION Pipeline and Hazardous Materials Safety Administration [Docket No... national attention and highlight the need for continued safety improvements to aging gas pipeline systems... 26, 1992) covering the continued use of cast iron pipe in natural gas distribution pipeline systems...

  17. Market bulletin - July 1989

    International Nuclear Information System (INIS)

    1989-01-01

    This bulletin deals with the brazilian electric power consumption in July 1989, containing data about the total consumption, the growth rates, the special tariffs and monthly evolution in each brazilian region. The economic indexes of industrial production, the market and the prices of electric power and petroleum products are also presented. (C.G.C.)

  18. Market bulletin - February 1989

    International Nuclear Information System (INIS)

    1989-01-01

    This bulletin deals with the brazilian electric power consumption in February 1989, containing data about the total consumption, the growth rates, the special tariffs and monthly evolution in each brazilian region. The economic indexes of industrial production, the market and the prices of electric power and petroleum products are also presented. (C.G.C.)

  19. 77 FR 26647 - National Building Safety Month, 2012

    Science.gov (United States)

    2012-05-04

    ... implementing state-of-the-art building safety, energy efficiency, and fire prevention codes and standards, they... our Nation's ability to withstand the threats and hazards we face. My Administration is committed to... disasters. We are drawing upon cutting edge science and technology to establish stronger codes and standards...

  20. OCRWM Bulletin

    International Nuclear Information System (INIS)

    1996-01-01

    This document is the Winter 1996 ORCWM Bulletin which is a report from the U.S. Department of Energy's Office of Civilian Radioactive Waste Management. Budget considerations and a discussion of waste policy forums are described. Several articles about the on-going site characterization at Yucca Mountain are included as a part of this bulletin.Tunnel excavations, meteorology studies, effects of seismic events, and design of a conveyor belt system are some of the topics covered in this issue

  1. New Bulletin: Latest News

    CERN Multimedia

    2005-01-01

    The paper version of the CERN Bulletin will be published twice a month with effect from 18 April 2005. The electronic version will be updated weekly. This year will see many changes in the Bulletin, designed to make it more economical, more compact and more attractive. From 18 April the paper version of the Bulletin will be published twice monthly, so we shall have to stop calling it the "Weekly". The purpose of this change in publication frequency is to redistribute the resources of the Publications Section of the Communications Group so that it can produce new brochures for the general public. However, so as not to compromise on topicality and communication of information, the Official News and General Information sections, the Pension Fund and training announcements and the seminar schedule will continue to be updated weekly. If you have signed up to be informed of the updates, you will continue to receive a weekly e-mail reminding you that the electronic version of the Bulletin has been updated. Offici...

  2. OCRWM Bulletin

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-04-01

    This document is the Winter 1996 ORCWM Bulletin which is a report from the U.S. Department of Energy`s Office of Civilian Radioactive Waste Management. Budget considerations and a discussion of waste policy forums are described. Several articles about the on-going site characterization at Yucca Mountain are included as a part of this bulletin.Tunnel excavations, meteorology studies, effects of seismic events, and design of a conveyor belt system are some of the topics covered in this issue.

  3. OCRWM Bulletin

    International Nuclear Information System (INIS)

    1995-01-01

    This document is the Spring 1995 ORCWM Bulletin which is a report from the U.S. Department of Energy's Office of Civilian Radioactive Waste Management. Budget considerations, public response to waste acceptance issues, and a discussion of waste policy forums are described. Several articles about the on-going site characterization at Yucca Mountain are included as a part of this bulletin. Detection of pathways for gases and fluids in the subsurface, hydrochemistry experiments, and a description of the appointment of a new Yucca Mountain Site Characterization Office project manager are some of the topics covered in this issue

  4. THR Bulletin

    African Journals Online (AJOL)

    Yasin

    factors and gender relations. This paper looks at the influence of the sex of a child on response to febrile illness. Materials and Methods. Study area. The study was carried out in Mbaise, Imo State,. Nigeria. Mbaise is one of the most culturally distinct rural communities in Imo State, with an. Tanzania Health Research Bulletin ...

  5. 49 CFR 385.333 - What happens at the end of the 18-month safety monitoring period?

    Science.gov (United States)

    2010-10-01

    ... SAFETY REGULATIONS SAFETY FITNESS PROCEDURES New Entrant Safety Assurance Program § 385.333 What happens at the end of the 18-month safety monitoring period? (a) If a safety audit has been performed within... the same basis as any other carrier. (d) If a safety audit or compliance review has not been performed...

  6. Posttraumatic stress disorder, depression, and perceived safety 13 months after September 11.

    Science.gov (United States)

    Grieger, Thomas A; Fullerton, Carol S; Ursano, Robert J

    2004-09-01

    This study assessed relationships between exposure to the September 11, 2001, terrorist attack, current posttraumatic stress disorder (PTSD), current major depression, and current safety perceptions in a sample of 212 Pentagon staff members 13 months after the attack. Forty-eight respondents (23 percent) had possible PTSD; eight (4 percent) had probable major depression. Respondents who were directly exposed to the attack were more likely to have PTSD and major depression and were less likely to have a perception of safety at work and in usual activities and travel only. In contrast, respondents with PTSD reported a lower perception of safety at home, at work, and in usual activities and travel.

  7. Annual bulletin of market 1990

    International Nuclear Information System (INIS)

    1990-01-01

    This bulletin deals with the brazilian electric power consumption in 1990 containing data about the total consumption, the growth rates, the special tariffs, and the monthly evolution in each brazilian region. The economic indexes of industrial production, the market and the prices of electric power and petroleum products are also presented. (C.G.C)

  8. Annual bulletin of market 1989

    International Nuclear Information System (INIS)

    1989-01-01

    This bulletin deals with the brazilian electric power consumption in 1989 containing data about the total consumption, the growth rates, the special tariffs, and the monthly evolution in each brazilian region. The economic indexes of industrial production, the market and the prices of electric power and petroleum products are also presented. (C.G.C)

  9. Evaluating effectiveness and safety toward electronic cigarette among Malaysian vapers: One-month observational study

    Directory of Open Access Journals (Sweden)

    Azizur Rahman

    2016-01-01

    Conclusion: A month follow-up showed a good smoking cessation rate among Malaysian vapers mainly in single users, whereas less number of quitters but the high reduction in tobacco cigarette consumption observed in dual users without any harmful effects. Furthermore, extended period studies are warranted to confirm its long-term safety and effectiveness among different Malaysian population.

  10. Social Security Bulletin

    Data.gov (United States)

    Social Security Administration — The Social Security Bulletin (ISSN 1937-4666) is published quarterly by the Social Security Administration. The Bulletin is prepared in the Office of Retirement and...

  11. Geomagnetic Indices Bulletin (GIB)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Geomagnetic Indices Bulletin is a one page sheet containing the magnetic indices Kp, Ap, Cp, An, As, Am and the provisional aa indices. The bulletin is published...

  12. Endangered Species Protection Bulletins

    Science.gov (United States)

    Endangered Species Protection Bulletins set forth geographically specific pesticide use limitations for the protection of threatened and endangered (listed) species and their designated critical habitat. Find out how to get and use Bulletins.

  13. Efficacy and Safety of Ibuprofen in Infants Aged Between 3 and 6 Months.

    Science.gov (United States)

    Ziesenitz, Victoria C; Zutter, Andreas; Erb, Thomas O; van den Anker, Johannes N

    2017-08-01

    Ibuprofen is a non-steroidal anti-inflammatory drug frequently administered to children of various ages for relief of fever and pain and is approved as an over-the-counter medication in many countries worldwide. Although there are extensive data on its efficacy and safety in children and adults, there are divergent dosing recommendations for analgesia and treatment of fever in infants, especially in the age group between 3 and 6 months of age. In this article, we have assessed the safety and efficacy of ibuprofen use in infants in an attempt to find the optimal method of pain and fever management in this specific age group. Based on the current evidence, short-term use of ibuprofen is considered safe in infants older than 3 months of age having a body weight above 5-6 kg when special attention is given to the hydration of the patient. Ibuprofen should be prescribed based on body weight using a dose of 5-10 mg/kg. This dose can be administered 3-4 times a day resulting in a maximum total daily dose of 30-40 mg/kg. The rectal route has been shown to be less reliable because of erratic absorption, especially in young infants. Since most efficacy and safety data have been derived from trials in infants with fever, future studies should focus on the efficacy of ibuprofen in young infants with pain.

  14. The Bulletin turns 50!

    CERN Document Server

    2015-01-01

    What does the Bulletin mean to you? Send us your thoughts!   Fifty years ago, on 30 March 1965, the CERN Bulletin – or the Weekly Bulletin as it was known in those days – was born. It was just a simple newsletter back then, but the Bulletin has changed over the years to become a proper magazine bringing together articles on scientific and technical subjects as well as the latest news from the Laboratory and its personnel. And so, over time, the CERN Bulletin has become - the editors would like to think – an icon of the Laboratory, to which the people of CERN are very attached. If you agree, please send us your comments! Whatever theme you want to highlight – reading habits, anecdotes, scientific discoveries – we’d like to hear what the Bulletin means to you. These messages will be published in our anniversary edition on 27 March. The CERN Bulletin team

  15. Ospemifene 12-month safety and efficacy in postmenopausal women with vulvar and vaginal atrophy

    DEFF Research Database (Denmark)

    Goldstein, S R; Bachmann, G A; Koninckx, P R

    2014-01-01

    OBJECTIVE: Assessment of 12-month safety of ospemifene 60 mg/day for treatment of postmenopausal women with vulvar and vaginal atrophy (VVA). METHODS: In this 52-week, randomized, double-blind, placebo-controlled, parallel-group study, women 40-80 years with VVA and an intact uterus were randomized...... baseline to week 12 in percentage of superficial and parabasal cells and vaginal pH. RESULTS: Of 426 randomized subjects, 81.9% (n = 349) completed the study with adverse events the most common reason for discontinuation (ospemifene 9.5%; placebo 3.9%). Most (88%) treatment-emergent adverse events...

  16. Children of Working Mothers. Special Labor Force Report. Bulletin 2158.

    Science.gov (United States)

    Bureau of Labor Statistics (DOL), Washington, DC.

    Part of a Special Labor Force Report series, this bulletin on children of working mothers discusses the increase in the number of children with working mothers as of March 1981, and describes major reasons for this growth. The bulletin consists of an article first published February 1982 in the "Monthly Labor Review," additional tables providing…

  17. Publication of the Bulletin

    CERN Multimedia

    The final edition (Nos 51-52/2009 and 1-2/2010) of the last Weekly Bulletin of the year will be published on Friday 11 December and will cover events at CERN from 14 December 2009 to 8 January 2010. Announcements for publication in this issue should reach the Publication Section (Communications group) or the Staff Association, as appropriate, by noon on Tuesday 8 December. Bulletin publication 2010 The table below lists the 2010 publication dates for the paper version of the Bulletin and the corresponding deadlines for the submission of announcements. Please note that all announcements must be submitted by 12.00 midday on Tuesdays at the latest. Bulletin No. Week number Submission of announcements (before 12.00 midday) Bulletin Web version Bulletin Paper version 2-3 Tuesday 5 January Friday 8 and 15 January Wednesday 13 J...

  18. Bulletin timetable for 2010

    CERN Multimedia

    CERN Bulletin

    2009-01-01

    The table below lists the 2010 publication dates for the paper version of the Bulletin and the corresponding deadlines for the submission of announcements. Please note that all announcements must be submitted by 12.00 midday on Tuesdays at the latest. Bulletin No. Week number Submission of announcements (before 12.00 midday) Bulletin Web version Bulletin Paper version 2-3 Tuesday 5 January Friday 8 and 15 January Wednesday 13 January 4-5 Tuesday 19 January Friday 22 and 29 January Wednesday 27 January 6-7 Tuesday 2 February Friday 5 and 12 february Wednesday 10 February 8-9 Tuesday 16 February Friday 19 and 26 February ...

  19. A 6-month large-scale study into the safety of tamsulosin

    Science.gov (United States)

    Michel, M C; Bressel, H-U; Goepel, M; Rübben, H

    2001-01-01

    Aims Tamsulosin is an α1-adrenoceptor antagonist for the treatment of symptomatic benign prostatic hyperplasia with a tolerability similar to that of placebo in short-term, placebo-controlled studies with limited patient numbers. The present study was designed to test the safety of tamsulosin treatment in a large cohort of men during a prolonged period of time, particularly with regard to comedications. Methods A multicentre, open-label phase IIIb study with 1784 patients receiving 0.4 mg o.d. tamsulosin for 6 months was performed according to good clinical practice guidelines. The analysis was performed on an intention-to-treat basis and powered to detect adverse events (AE) occurring in 0.15% of patients with 95% confidence. Results During a total drug exposure time of 811 patient years, 386 AE were recorded in 253 patients (14.2%; 95% confidence intervals [CI] 12.0–15.2%). Twenty-nine patients suffered 44 serious AE including five fatal events (CI 0.12–0.73%) due to myocardial infarction (n = 3) and to pneumonia and a car accident (one each), but all deaths were judged to be unlikely to be related to study medication. The frequency of AE in patients without any comedication (n = 1095) was 13.0% (CI 11.3–14.9%). In a logistic regression analysis β-adrenoceptor blockers, converting enzyme inhibitors, antidiabetics and diuretics did not significantly affect the odds ratio for having AE. However, concomitant α-adrenoceptor antagonists (a protocol violation) and treatment with verapamil (which also has α-adrenoceptor antagonist activity) significantly enhanced the odds ratio for having AE to 3.87 (CI 1.52–9.85) and 3.17 (CI 1.52–6.58), respectively. Minor increases in the odds ratio, which did not reach statistical significance, were also observed for Ca2+ antagonists other than verapamil and for nitrates. Conclusions We conclude that tamsulosin has a good safety profile relative to AE rates in the placebo arms of previous studies on tamsulosin even in

  20. Market bulletin and own load - October 1991

    International Nuclear Information System (INIS)

    1991-01-01

    This bulletin deals with the brazilian electric power consumption in October 1991, containing data about the total consumption, the growth rates, the special tariffs and monthly evolution in each brazilian region. The economic indexes of industrial production, the market and the prices of electric power and petroleum products are also presented. (C.G.C.)

  1. Market bulletin and own load - June 1992

    International Nuclear Information System (INIS)

    1992-01-01

    This bulletin deals with the brazilian electric power consumption in June 1992, containing data about the total consumption, the growth rates, the special tariffs and monthly evolution in each brazilian region. The economic indexes of industrial production, the market and the prices of electric power and petroleum products are also presented. (C.G.C.)

  2. Market bulletin and own load - April 1992

    International Nuclear Information System (INIS)

    1992-01-01

    This bulletin deals with the brazilian electric power consumption in April 1992, containing data about the total consumption, the growth rates, the special tariffs and monthly evolution in each brazilian region. The economic indexes of industrial production, the market and the prices of electric power and petroleum products are also presented. (C.G.C.)

  3. Market bulletin and own load - September 1992

    International Nuclear Information System (INIS)

    1992-01-01

    This bulletin deals with the brazilian electric power consumption in September 1992, containing data about the total consumption, the growth rates, the special tariffs and monthly evolution in each brazilian region. The economic indexes of industrial production, the market and the prices of electric power and petroleum products are also presented. (C.G.C.)

  4. Market and own load bulletin - May 1993

    International Nuclear Information System (INIS)

    1993-01-01

    This bulletin shows the Brazilian electric power consumption in May 1993, containing data about the total consumption, the growth rates, the special tariffs and monthly evolution in each Brazilian region. The economic indexes of industrial production, the market, the prices of electric power and petroleum products are also presented. (M.V.M.)

  5. Market bulletin and own load - August 1992

    International Nuclear Information System (INIS)

    1992-01-01

    This bulletin deals with the brazilian electric power consumption in August 1992, containing data about the total consumption, the growth rates, the special tariffs and monthly evolution in each brazilian region. The economic indexes of industrial production, the market and the prices of electric power and petroleum products are also presented. (C.G.C.)

  6. Market and own load bulletin - January 1993

    International Nuclear Information System (INIS)

    1993-01-01

    This bulletin shows the Brazilian electric power consumption in January 1993, containing data about the total consumption, the growth rates, the special tariffs and monthly evolution in each Brazilian region. The economic indexes of industrial production, the market, the prices of electric power and petroleum products are also presented. (M.V.M.)

  7. Market and own load bulletin - February 1993

    International Nuclear Information System (INIS)

    1993-01-01

    This bulletin shows the Brazilian electric power consumption in February 1993, containing data about the total consumption, the growth rates, the special tariffs and monthly evolution in each Brazilian region. The economic indexes of industrial production, the market, the prices of electric power and petroleum products are also presented. (M.V.M.)

  8. Market bulletin and own load - September 1991

    International Nuclear Information System (INIS)

    1991-01-01

    This bulletin deals with the brazilian electric power consumption in September 1991, containing data about the total consumption, the growth rates, the special tariffs and monthly evolution in each brazilian region. The economic indexes of industrial production, the market and the prices of electric power and petroleum products are also presented. (C.G.C.)

  9. Market bulletin and own load - March 1992

    International Nuclear Information System (INIS)

    1992-01-01

    This bulletin deals with the brazilian electric power consumption in March 1992, containing data about the total consumption, the growth rates, the special tariffs and monthly evolution in each brazilian region. The economic indexes of industrial production, the market and the prices of electric power and petroleum products are also presented. (C.G.C.)

  10. Market and own load bulletin - March 1993

    International Nuclear Information System (INIS)

    1993-01-01

    This bulletin shows the Brazilian electric power consumption in March 1993, containing data about the total consumption, the growth rates, the special tariffs and monthly evolution in each Brazilian region. The economic indexes of industrial production, the market, the prices of electric power and petroleum products are also presented. (M.V.M.)

  11. Market and own load bulletin - November 1992

    International Nuclear Information System (INIS)

    1992-01-01

    This bulletin shows the Brazilian electric power consumption in November 1993, containing data about the total consumption, the growth rates, the special tariffs and monthly evolution in each Brazilian region. The economic indexes of industrial production, the market, the prices of electric power and petroleum products are also presented. (M.V.M.)

  12. Market bulletin and own load - May 1992

    International Nuclear Information System (INIS)

    1992-01-01

    This bulletin deals with the brazilian electric power consumption in May 1992, containing data about the total consumption, the growth rates, the special tariffs and monthly evolution in each brazilian region. The economic indexes of industrial production, the market and the prices of electric power and petroleum products are also presented. (C.G.C.)

  13. A major safety overhaul

    CERN Multimedia

    2003-01-01

    A redefined policy, a revamped safety course, an environmental project... the TIS (Technical Inspection and Safety) Division has begun a major safety overhaul. Its new head, Wolfgang Weingarten, explains to the Bulletin why and how this is happening.

  14. Publication of the bulletin

    CERN Multimedia

    2007-01-01

    The final edition (Nos 51-52/2007 and 1-2-3/2008) of the last Bulletin of the year will appear on Friday 14 December and will cover events at CERN from 17 December 2007 to 18 January 2008. Announcements for publication in this issue should reach the Publication Section (Communication group) or the Staff Association, as appropriate, by noon on Tuesday 11 December. The table below lists the 2008 publication dates for the paper version of the Bulletin and the corresponding deadlines for the submission of announcements. Please note that all announcements must be submitted by 12.00 midday on Tuesdays at the latest. Bulletin publication 2008 Bulletin N° 4-5 Publication: Monday 21 january Submission deadline for announcements: Tuesday 15 January Bulletin N° 6-7 Publication: Monday 4 february Submission deadline for announcements: Tuesday 29 January Bulletin N° 8-9 Publication: Monday 18 february Submission deadline for announcements: Tuesday 12 February Bulletin N° 10-11 P...

  15. CBP Quota Bulletins

    Data.gov (United States)

    Department of Homeland Security — Quota information is issued for the trade community by the Quota Enforcement Administration Branch within the Office of International Trade. The Quota Bulletins have...

  16. IDRC Bulletin #127

    International Development Research Centre (IDRC) Digital Library (Canada)

    Subscribe | Unsubscribe. Subscribe to IDRC's regional newsletters. Asia | Latin America and the Caribbean | Middle East and North Africa | Sub-Saharan Africa Questions or comments? Send us your feedback at bulletin@idrc.ca. Canada ...

  17. Publication of the bulletin

    CERN Document Server

    DSU Unit

    2008-01-01

    The final edition (Nos 51-52/2008 and 1-2/2009) of the last Weekly Bulletin of the year will be published on Friday 12 December and will cover events at CERN from 15 December 2008 to 12 January 2009. Announcements for publication in this issue should reach the Publication Section (Communication group) or the Staff Association, as appropriate by noon, on Tuesday 9 December. Bulletin publication 2009 The table below lists the 2009 publication dates for the paper version of the Bulletin and the corresponding deadlines for the submission of announcements. Please note that all announcements must be submitted by 12.00 midday on Tuesdays at the latest. Bulletin No. Week number Submission of announcements (before 12.00 midday) Publication date 3-4 Tuesday 6 January Monday 12 January 5-6 Tuesday 20 January Monday 26 January 7-8 Tuesday 3 February Monday 9 February 9-10 Tuesday 17 Februar...

  18. Elevate Anterior/Apical: 12-Month Data Showing Safety and Efficacy in Surgical Treatment of Pelvic Organ Prolapse

    NARCIS (Netherlands)

    Stanford, Edward J.; Moore, Robert D.; Roovers, Jan-Paul W. R.; Courtieu, Christophe; Lukban, James C.; Bataller, Eduardo; Liedl, Bernhard; Sutherland, Suzette E.

    2013-01-01

    Objective: This study aimed to assess the safety and efficacy of the Elevate Anterior/Apical transvaginal mesh procedure in pelvic organ prolapse (POP) repair at 12-months follow-up. Methods: This prospective, multicenter, multinational study enrolled 142 patients experiencing anterior vaginal

  19. Pivotal ERIVANCE basal cell carcinoma (BCC) study: 12-month update of efficacy and safety of vismodegib in advanced BCC.

    Science.gov (United States)

    Sekulic, Aleksandar; Migden, Michael R; Lewis, Karl; Hainsworth, John D; Solomon, James A; Yoo, Simon; Arron, Sarah T; Friedlander, Philip A; Marmur, Ellen; Rudin, Charles M; Chang, Anne Lynn S; Dirix, Luc; Hou, Jeannie; Yue, Huibin; Hauschild, Axel

    2015-06-01

    Primary analysis from the pivotal ERIVANCE BCC study resulted in approval of vismodegib, a Hedgehog pathway inhibitor indicated for treatment of adults with metastatic or locally advanced basal cell carcinoma (BCC) that has recurred after surgery or for patients who are not candidates for surgery or radiation. An efficacy and safety analysis was conducted 12 months after primary analysis. This was a multinational, multicenter, nonrandomized, 2-cohort study in patients with measurable and histologically confirmed locally advanced or metastatic BCC taking oral vismodegib (150 mg/d). Primary outcome measure was objective response rate (complete and partial responses) assessed by independent review facility. After 12 months of additional follow-up, median duration of exposure to vismodegib was 12.9 months. Objective response rate increased from 30.3% to 33.3% in patients with metastatic disease, and from 42.9% to 47.6% in patients with the locally advanced form. Median duration of response in patients with locally advanced BCC increased from 7.6 to 9.5 months. No new safety signals emerged with extended treatment duration. Limitations include low prevalence of advanced BCC and challenges of designing a study with heterogenous manifestations. The 12-month update of the study confirms the efficacy and safety of vismodegib in management of advanced BCC. Copyright © 2015 American Academy of Dermatology, Inc. Published by Elsevier Inc. All rights reserved.

  20. Bulletin Survey - Early Results

    CERN Multimedia

    2002-01-01

    There was a good response to our questionnaire on the Bulletin (around 450 so far). Many thanks to all of you - your views are invaluable to us. Pending publication of the full figures, which will give latecomers time to take part in the survey, here we give here answers some of your most frequent comments. Thank you for the many warm tributes and messages of encouragement we received. We also received criticisms about the way information is handled in the Bulletin and on its circulation. In today's issue we reply to these two points. Why is the Bulletin politically correct ? Many respondents reproach the Bulletin for a lack of objectivity and for being too politically correct to the point of being a propaganda organ. It is true that the Bulletin is not a newspaper, but rather a bulletin of communication (like SLAC's Beam Line). What is the difference ? A newspaper is objectively independent of the subjects it reports on, and when its reporters write stories they dig around for information from all parties...

  1. Bulletin Survey: Technical clarifications

    CERN Multimedia

    2002-01-01

    In the latest of our articles on the results of the Bulletin survey, we respond to some of your technical comments on the Electronic Bulletin. Many thanks to the more than 500 of you who completed the questionnaire. The full statistics will be published next week. 'It takes too long to download the pages' Yes, it's true that the Electronic Bulletin's download time isn't perfect but it will improve when the Bulletin migrates to another, faster database. 'I find it very difficult to locate all the articles' Some people experience difficulty negotiating their way through the Bulletin once they have entered a specific section. The blue column on the left contains an 'In this issue' link taking you to the other sections. What's more, the whole of the paper Bulletin is available in the electronic version. As the latter is relatively new, however, it will take a bit of time to get used to browsing through it. Many of you say that it's still too early to form an opinion. 'Pull-down menus would be good, so that yo...

  2. Six-month gonadotropin releasing hormone (GnRH agonist depots provide efficacy, safety, convenience, and comfort

    Directory of Open Access Journals (Sweden)

    Phillips JM

    2011-07-01

    Full Text Available E David Crawford, Jason M PhillipsUniversity of Colorado Health Sciences Center, Aurora, CO, USAAbstract: Two different 6-month GnRH agonist depot formulations approved for palliative treatment of advanced and metastatic prostate cancer in the United States – leuprolide acetate 45 mg and triptorelinpalmoate 22.5 mg – provide patients with efficacy and safety comparable to those of existing 1-, 3-, and 4-month GnRH agonist depots. However, the 6-month formulations can increase patient convenience, comfort, and compliance by reducing the number of physician visits and injections required. At the conclusion of their pivotal trials, the 6-month formulations demonstrated efficacy rates in achieving chemical castration (serum testosterone #50 ng/dL that ranged between 93% and 99%. As with existing GnRH agonist depot formulations, hot flashes represented the most common adverse event reported in trials of 6-month leuprolide acetate or triptorelin. As such, these products may prove useful not only for their labeled indication, but also as adjuncts to other treatments such as radical prostatectomy, radiotherapy, and chemotherapy. We recommend further research, including head-to-head trials between the 6-month GnRH depots, to refine our understanding of these products.Keywords: prostate cancer, leuprorelin, leuprolide, triptorelin, 6-month depot, testosterone

  3. Nuclear Law Bulletin Index Nos. 1 to 99

    International Nuclear Information System (INIS)

    2017-01-01

    This new edition of the Nuclear Law Bulletin Index covers the first 99 issues of the Nuclear Law Bulletin (NLB). By established practice, the plan of the Index is not a replica of the Bulletin, as it was considered more useful for research purposes to group together all the information concerning legislative and regulatory activities, case law and bilateral agreements and to classify this information by country. Following classification by country, references to the work of international organisations, multilateral agreements, studies and articles are set out in separate sections. The 'Bibliography and News Briefs' section is omitted from the Index. A separate chapter of the Index has been devoted to the listing of the instruments published in the Supplements to the Bulletin, or in the Chapter 'Texts' from past Bulletins, up until the present date. Each item in the Index is followed by a reference to the relevant Bulletin. Legislative and regulatory texts, as well as agreements reproduced in the Bulletins or their Supplements, are also referenced. Plan of index: 1 - Reports and commentary 1a - Classification by country Legislative and regulatory activities (Environmental protection, Food irradiation, General legislation, regulations and instruments, International co-operation, Liability and compensation, Licensing and regulatory infrastructure, Nuclear installations, Nuclear safety and radiological protection - including nuclear emergency planning, Nuclear security, Nuclear trade - including non-proliferation, Nuclear-powered ships, Organisation and structure, Radioactive materials - including physical protection, Radioactive waste management, Transport of radioactive materials); Case law; Administrative decisions; Agreements; 1b - International organisations; 1c - Multilateral agreements; 2 - Studies and articles; 3 - Texts reproduced in the nuclear law bulletin; 3a - Classification by country; 3b - International organisations; 3c

  4. EUDISED R & D Bulletin.

    Science.gov (United States)

    Council of Europe, Strasbourg (France). Documentation Center for Education in Europe.

    The EUDISED project, which was started in 1968, is a computer-based network of national agencies dealing with the main fields of educational information. Listed in this bulletin for 1976 are on-going and completed projects in educational research and development reported from Austria, Finland, France, Federal Republic of Germany, Norway, Spain,…

  5. Patent foramen ovale closure using a bioabsorbable closure device: safety and efficacy at 6-month follow-up.

    Science.gov (United States)

    Van den Branden, Ben J; Post, Martijn C; Plokker, Herbert W; ten Berg, Jurriën M; Suttorp, Maarten J

    2010-09-01

    The aim of this study was to assess the mid-term safety and efficacy of percutaneous patent foramen ovale (PFO) closure using a bioabsorbable device (BioSTAR, NMT Medical, Boston, Massachusetts). Closure of PFO in patients with cryptogenic stroke has proven to be safe and effective using different types of permanent devices. All consecutive patients who underwent percutaneous PFO closure with the bioabsorbable closure device between November 2007 and January 2009 were included. Residual shunt was assessed using contrast transthoracic echocardiography. Sixty-two patients (55% women, mean age 47.7 ± 11.8 years) underwent PFO closure. The in-hospital complications were a surgical device retrieval in 2 patients (3.2%), device reposition in 1 (1.6%), and a minimal groin hematoma in 6 patients (9.7%). The short-term complications at 1-month follow-up (n = 60) were a transient ischemic attack in the presence of a residual shunt in 1 patient and new supraventricular tachycardia in 7 patients (11.3%). At 6-month follow-up (n = 60), 1 patient without residual shunt developed a transient ischemic attack and 1 developed atrial fibrillation. A mild or moderate residual shunt was noted in 51.7%, 33.9%, and 23.7% after 1-day, 1-month, and 6-month follow-up, respectively. A large shunt was present in 8.3%, 3.4%, and 0% after 1-day, 1-month, and 6-month follow-up. Closure of PFO using the bioabsorbable device is associated with a low complication rate and a low recurrence rate of embolic events. However, a relatively high percentage of mild or moderate residual shunting is still present at 6-month follow-up. Copyright © 2010 American College of Cardiology Foundation. Published by Elsevier Inc. All rights reserved.

  6. Evaluating effectiveness and safety toward electronic cigarette among Malaysian vapers: One-month observational study

    OpenAIRE

    Azizur Rahman; Mohamad Haniki Nik Mohamad; Shazia Jamshed

    2016-01-01

    Objective: Electronic cigarette (e-cig) is recently growing substitute for smoking. The attention and practice of e-cig among consumers is expanded globally, and Malaysia is not an exception to this, but the paucity of local data motivates us to do the current research. Methods: A total of 220 e-cig vapers recruited for the study and divided into two categories based on smoking status as a single user and dual user. Both users observed for 1 month period to assess smoking cessation rate, a...

  7. Twelve-month safety and efficacy of inhaled fluticasone propionate in children aged 1 to 3 years with recurrent wheezing

    DEFF Research Database (Denmark)

    Bisgaard, Hans; Allen, David; Milanowski, Janusz

    2004-01-01

    , exacerbations, and requirements for oral steroid treatment and more symptom-free days and days without use of rescue treatment. CONCLUSIONS: Twelve months of treatment with inhaled FP (100 microg twice daily) in preschool children aged 1 to 3 years with recurrent wheeze has no effect on growth and no other......OBJECTIVE: Our aim was to compare the 12-month safety and efficacy of fluticasone propionate (FP) and sodium cromoglycate (SCG) in children aged 1 to 3 years with mild to moderate recurrent wheeze. METHODS: The study was a randomized, parallel-group, open-label multicenter study of 625 children......, aged 1 to 3 years, with recurrent wheeze randomized in a 3:1 ratio to treatment for 52 weeks with FP (100 microg twice daily) via metered-dose inhaler and Babyhaler spacer device or SCG (5 mg 4 times daily) via metered-dose inhaler and Nebuhaler spacer device, respectively. RESULTS...

  8. Satisfactory safety and immunogenicity of MSP3 malaria vaccine candidate in Tanzanian children aged 12–24 months

    Directory of Open Access Journals (Sweden)

    Segeja Method D

    2009-07-01

    Full Text Available Abstract Background Development and deployment of an effective malaria vaccine would complement existing malaria control measures. A blood stage malaria vaccine candidate, Merozoite Surface Protein-3 (MSP3, produced as a long synthetic peptide, has been shown to be safe in non-immune and semi-immune adults. A phase Ib dose-escalating study was conducted to assess the vaccine's safety and immunogenicity in children aged 12 to 24 months in Korogwe, Tanzania (ClinicalTrials.gov number: NCT00469651. Methods This was a double-blind, randomized, controlled, dose escalation phase Ib trial, in which children were given one of two different doses of the MSP3 antigen (15 μg or 30 μg or a control vaccine (Engerix B. Children were randomly allocated either to the MSP3 candidate malaria vaccine or the control vaccine administered at a schedule of 0, 1, and 2 months. Immunization with lower and higher doses was staggered for safety reasons starting with the lower dose. The primary endpoint was safety and reactogenicity within 28 days post-vaccination. Blood samples were obtained at different time points to measure immunological responses. Results are presented up to 84 days post-vaccination. Results A total of 45 children were enrolled, 15 in each of the two MSP3 dose groups and 15 in the Engerix B group. There were no important differences in reactogenicity between the two MSP3 groups and Engerix B. Grade 3 adverse events were infrequent; only five were detected throughout the study, all of which were transient and resolved without sequelae. No serious adverse event reported was considered to be related to MSP3 vaccine. Both MSP3 dose regimens elicited strong cytophilic IgG responses (subclasses IgG1 and IgG3, the isotypes involved in the monocyte-dependant mechanism of Plasmodium falciparum parasite-killing. The titers reached are similar to those from African adults having reached a state of premunition. Furthermore, vaccination induced seroconversion in

  9. bulletin Publication 2009

    CERN Document Server

    DSU Unit

    2008-01-01

    The table below lists the 2009 publication dates for the paper version of the Bulletin and the corresponding deadlines for the submission of announcements. Please note that all announcements must be submitted by 12.00 midday on Tuesdays at the latest. Bulletin No. Week number Submission of announcements (before 12.00 midday) Publication date 3-4 Tuesday 6 January Monday 12 January 5-6 Tuesday 20 January Monday 26 January 7-8 Tuesday 3 February Monday 9 February 9-10 Tuesday 17 February Monday 23 February 11-12 Tuesday 3 March Monday 9 March 13-14 Tuesday 17 March Monday 23 March 15-16-17 (Easter issue) Tuesday 31 March Monday 6 April 18-19 Tuesday 21 April Monday 27 April 20-21 Tuesday 5 May Monday 11 May 22-23 Tuesday 19 May Monday 25 May 24-25 ...

  10. Environmental guidance regulatory bulletin

    International Nuclear Information System (INIS)

    1997-01-01

    This document describes the background on expanding public participation in the Resource Conservation and Recovery Act and DOE's response. The bulletin also describes the changes made by the final rule to existing regulations, guidance provided by EPA in the preamble and in the revised RCRA Public Participation Manual, the relationship between public participation and environmental justice, and DOE's recent public participation and environmental justice initiatives

  11. Bulletin of Materials Science | News

    Indian Academy of Sciences (India)

    Home; Journals; Bulletin of Materials Science. M K Rabinal. Articles written in Bulletin of Materials Science. Volume 35 Issue 4 August 2012 pp 529-532. An optical tweezer-based study of antimicrobial activity of silver nanoparticles · Yogesha Sarbari Bhattacharya M K Rabinal Sharath Ananthamurthy · More Details Abstract ...

  12. Safety and efficacy of levetiracetam for the treatment of partial onset seizures in children from one month of age

    Directory of Open Access Journals (Sweden)

    Cormier J

    2013-02-01

    Full Text Available Justine Cormier, Catherine J ChuMassachusetts General Hospital, Department of Neurology, Programs in Child Neurology and Neurophysiology, Boston, MA, USAAbstract: Epilepsy is a common neurological disorder in the pediatric population, affecting up to one percent of children, and for which the mainstay of treatment is anticonvulsant medication. Despite the frequent use of anticonvulsant drugs, remarkably little is known about the safety and efficacy of most of these medications in the pediatric epilepsy population. Of 34 anticonvulsants currently approved for use by the US Food and Drug Administration (FDA, only 13 have been approved for use in children. Although infants and young children are disproportionately affected by epilepsy, there are currently only three anticonvulsant medications that have been specifically evaluated and approved for use in children younger than 2 years of age. In 2012, the FDA approved levetiracetam as an adjunctive treatment for partial onset seizures in infants and children from one month of age. Here we review the available data on levetiracetam in the pediatric epilepsy population. We first discuss the pharmacological profile of levetiracetam, including its mechanism of action, formulations and dosing, and pharmacokinetics in children. We then review the available efficacy, safety, and tolerability data in children from one month of age with partial onset seizures. We conclude that the current data leading to the approval of levetiracetam for use in infants and children with partial onset seizures is encouraging, although more work needs to be done before definitive conclusions can be drawn about the efficacy of levetiracetam across different pediatric age groups.Keywords: levetiracetam, anticonvulsant drug, partial seizures, pediatric epilepsy

  13. The new Bulletin has arrived!

    CERN Multimedia

    2006-01-01

    This edition of the CERN Bulletin is the first with a new layout for the paper version. Its innovations include a more attractive format, as well as the printing of the English and French texts on inverted pages, the two distinguishable by the colour of the header on the first page (green for the English and blue for the French). This and the use of pictograms to identify the various sections make the whole thing easier to read. The introduction of this new formula coincides with the addition of a new section, a monthly column called 'A Word from the DG,' in which the Director-General will give an update on the main issues facing CERN and particle physics. The coming months will see the introduction of other new sections. Last but not least, the weekly timetable of seminars, showing the title, date and speaker, now appears in the middle of the paper version rather than at the end. Summaries are published only on the Web. All these changes are accompanied by new distribution arrangements. You will find pap...

  14. Safety of docosahexaenoic acid (DHA) administered as DHA ethyl ester in a 9-month toxicity study in dogs.

    Science.gov (United States)

    Dahms, Irina; Beilstein, Paul; Bonnette, Kimberly; Salem, Norman

    2016-06-01

    DHA Ethyl Ester (DHA-EE) is a 90% concentrated ethyl ester of docosahexaenoic acid manufactured from the microalgal oil. The objective of the 9-month study was to evaluate safety of DHA-EE administered to beagle dogs at dose levels 150, 1000 and 2000 mg/kg bw/day by oral gavage and to determine reversibility of any findings after a 2-month recovery period. DHA-EE was well tolerated at all doses. There were observations of dry flaky skin with occasional reddened areas at doses ≥1000 mg/kg bw/day. These findings lacked any microscopic correlate and were no longer present after the recovery period. There were no toxicologically relevant findings in body weights, body weight gains, food consumption, ophthalmological examinations, and ECG measurements. Test article-related changes in hematology parameters were limited to decreases in reticulocyte count in the high-dose males and considered non-adverse. In clinical chemistry parameters, dose-related decreases in cholesterol and triglycerides levels were observed at all doses in males and females and attributed to the known lipid-lowering effects of DHA. There were no effects on other clinical chemistry, urinalysis or coagulation parameters. There were no abnormal histopathology findings attributed to test article. The No-Observable-Adverse-Effect Level of DHA-EE was established at 2000 mg/kg bw/day for both genders. Copyright © 2016 Elsevier Ltd. All rights reserved.

  15. Development and evaluation of an electronic drug and therapeutics bulletin.

    Science.gov (United States)

    Alderman, Christopher P

    2002-10-01

    To describe the development, implementation, and initial evaluation of a paperless drug and therapeutics bulletin that is distributed by electronic mail from the pharmacy department of an Australian teaching hospital. A standardized format for the bulletin was designed and approved in February 2001. The aim of the bulletin is to facilitate the timely dissemination of concise, factual information about issues of current interest in therapeutics, drug safety, and the cost-effective use of medicines. A simple and attractive graphic design was chosen, and the hospital's clinical pharmacists and drug information staff developed an initial bank of content during the period immediately preceding the launch. The bulletin is presented as a 1-page, read-only file in Word for Windows format and was initially distributed by electronic mail to all users of the hospital's computerized communication network. As the popularity of the bulletin increased, healthcare practitioners from outside of the hospital began to request permission for inclusion on the circulation list, and the content was frequently forwarded by E-mail to workers in other hospitals and community-based settings. The bulletin is now distributed to pharmacists around Australia via 2 separate moderated discussion lists, one of which provides an archive site for previous editions. Healthcare workers in Singapore, the US, Canada, and New Zealand also receive the bulletin, which is now also abstracted by a major Australian pharmacy journal. A readership survey (also electronically distributed) was used to seek feedback after the publication of the first 12 editions. Readers indicated a high level of satisfaction with the content, format, and frequency of distribution of the materials. Although the concept and execution of this project was relatively simple, an extensive literature review did not reveal any previously published reports describing this type of approach to the distribution of a pharmacy bulletin. The

  16. Do not miss the Announcements and Events sections of the Bulletin!

    CERN Document Server

    2013-01-01

    There you'll find the availability of Services during the annual closure, the closure of the telephone switchboard, the Bulletin publication schedule for 2014, a pilot eduroam service at CERN, HSE Safety Bulletin 2013-4, new Swiss traffic rules, information about the infirmary's closure, the start of Horizon 2020, information on the CERN car stickers 2014... this information is FOR YOU!  

  17. Self-help on-line: an outcome evaluation of breast cancer bulletin boards.

    Science.gov (United States)

    Lieberman, Morton A; Goldstein, Benjamin A

    2005-11-01

    Many breast cancer patients find help from on-line self-help groups, consisting of self-directed, asynchronous, bulletin boards. These have yet to be empirically evaluated. Upon joining a group and 6 months later, new members (N=114) to breast cancer bulletin boards completed measures of depression (CES-D), growth (PTGI) and psychosocial wellbeing (FACT-B). Improvement was statistically significant on all three measures. This serves as a first validation of Internet bulletin boards as a source of support and help for breast cancer patients. These boards are of particular interest because they are free, accessible and support comes from peers and not from professional facilitators.

  18. Bulletin of Materials Science | News

    Indian Academy of Sciences (India)

    Home; Journals; Bulletin of Materials Science; Volume 39; Issue 1 .... Na + /B 3 + phosphor has a potential application in white light-emitting diodes based ... College of Mathematics and Physics, Jinggangshan University, Ji'an 343009, China ...

  19. Bulletin of Materials Science | News

    Indian Academy of Sciences (India)

    Home; Journals; Bulletin of Materials Science; Volume 38; Issue 3 ... In this study, a modified model for the application of the thermionic and hopping current ... Departments of Mathematics and Physics, Arab American University, Jenin 240, ...

  20. ENGINEERING BULLETIN: SUPERCRITICAL WATER OXIDATION

    Science.gov (United States)

    This engineering bulletin presents a description and status of supercritical water oxidation technology, a summary of recent performance tests, and the current applicability of this emerging technology. This information is provided to assist remedial project managers, contractors...

  1. Bulletin of International Simultaneous Observations

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The publication of the Bulletin of International Simultaneous Observations, began July 1, 1875, with daily maps added in 1877. It was published for distribution...

  2. Nuclear Law Bulletin: Index + supplement no.56

    International Nuclear Information System (INIS)

    Anon.

    1995-01-01

    This book deals with the status of legislation governing the peaceful uses of nuclear energy in Central and Eastern European Countries. Readers are informed about regulatory and institutional developments in these countries. The Supplement to this Bulletin reproduces the Ukraine fundamental nuclear law of the 8 february 1995 on the use of nuclear energy and radiation safety. It shall establish the priority of human and environmental safety and the rights and responsibilities of citizens with regard to the use of nuclear energy, it shall regulate activities connected with the use of nuclear installations and ionizing radiation sources, and, as well, establish the legal basis for Ukraine's international commitments with respect to the use of nuclear energy. (authors). 71 refs

  3. Technology applications bulletins

    International Nuclear Information System (INIS)

    Koncinski, W. Jr.

    1989-02-01

    Martin Marietta Energy Systems, Inc. (Energy Systems), operates five facilities for the US Department of Energy (DOE): the Oak Ridge National Laboratory (ORNL), which is a large, multidisciplinary research and development (R and D) center whose primary mission is energy research; the Oak Ridge Y-12 Plant, which engages in defense research, development, and production; and the uranium-enrichment plants at Oak Ridge; Paducah, Kentucky; and Portsmouth, Ohio. Much of the research carried out at these facilities is of interest to industry and to state or local governments. To make information about this research available, the Energy Systems Office of Technology Applications publishes brief descriptions of selected technologies and reports. These technology applications bulletins describe the new technology and inform the reader about how to obtain further information, gain access to technical resources, and initiate direct contact with Energy Systems researchers

  4. Getting in touch with the Bulletin team

    CERN Multimedia

    DSU Department

    2008-01-01

    The e-mail address for sending articles to the Bulletin has changed. To simplify the procedure, all articles and suggestions for articles (News, Official News, General Information) should be sent to the following address: Bulletin-Editors@cern.ch Thank you for your cooperation. The Bulletin team (DSU/CO-CC)

  5. Efficacy and Safety of Monthly versus Quarterly Ranibizumab Treatment in Neovascular Age-related Macular Degeneration: The EXCITE Study

    NARCIS (Netherlands)

    Schmidt-Erfurth, Ursula; Eldem, Bora; Guymer, Robyn; Korobelnik, Jean-Franc̦ois; Schlingemann, Reinier O.; Axer-Siegel, Ruth; Wiedemann, Peter; Simader, Christian; Gekkieva, Margarita; Weichselberger, Andreas

    2011-01-01

    Objective: To demonstrate noninferiority of a quarterly treatment regimen to a monthly regimen of ranibizumab in patients with subfoveal choroidal neovascularization (CNV) secondary to age-related macular degeneration (AMD). Design: A 12-month, multicenter, randomized, double-masked,

  6. Don't miss the Announcements and Events sections of the Bulletin!

    CERN Multimedia

    2014-01-01

    There you'll find information on the 2014 European School of High-Energy Physics, the seventh Inverted CERN School of Computing, the Safety Guideline GS 0-0-1, the Safety Bulletin 2014-1, the final public lecture by Jan Peters... this information is FOR YOU!

  7. Effectiveness and safety of a 6-month treatment with paricalcitol in patients on hemodialysis with secondary hyperparathyroidism.

    Science.gov (United States)

    Olaizola, Inés; Caorsi, Hena; Fajardo, Laura; Ferreiro, Alejandro; Campistrus, Nieves; Dolinsky, Deyanira; Petraglia, Alicia; Ambrosoni, Pablo

    2016-01-01

    The mineral bone disorder, particularly secondary hyperparathyroidism, in chronic kidney disease (CKD) has a systemic impact affecting not only bone metabolism. Therefore its correction is important to prevent cardiovascular, inflammatory and immune diseases. To assess the effectiveness and safety of intravenous paricalcitol administered over a 6 month period for the treatment of secondary hyperparathyroidism (SHPT) in patients undergoing conventional hemodialysis, with close follow-up of treatment response. A phase 4 clinical trial was performed comparing clinical and laboratory data before and after 6 months of treatment. SHPT patients undergoing hemodialysis who were naïve to vitamin D metabolites or had failed to current therapy were included. Clinical and laboratory characteristics were analyzed. Efficacy analyses were based on intact parathyroid hormone (iPTH) levels and were performed using data from patients who completed 6 months of treatment. Nineteen of the 26 patients enrolled completed 6 months of treatment. All patients exhibited reduced baseline iPTH levels (mean reduction, 371.8 pg/mL; 95% CI, 273.3-470.2 pg/mL]; 17 patients (89.5%) had reductions exceeding 30%. Twelve patients (63%) achieved therapeutic success (defined as iPTH serum levels 150-300 pg/mL), with a median time of 2 months from the beginning of treatment. All reported episodes of hypercalcemia (n = 2) and hyperphosphatemia (n = 34) were asymptomatic. No major therapy-related serious AEs were reported. Paricalcitol was safely administered and was associated with significant decreases in iPTH levels over the study period. A doença metabólica óssea, em particular o hiperparatireoidismo secundário, na doença renal crônica (DRC) tem um impacto sistêmico que afeta nem só o metabolismo ósseo. Por tanto, sua correção é importante para prevenir as doenças do sistema imunitário, inflamatório e cardiovascular. Avaliar a eficácia e a segurança do paricalcitol intravenoso

  8. The Meteoritical Bulletin, No. 103

    Science.gov (United States)

    Ruzicka, Alex; Grossman, Jeffrey; Bouvier, Audrey; Agee, Carl B.

    2017-05-01

    Meteoritical Bulletin 103 contains 2582 meteorites including 10 falls (Ardón, Demsa, Jinju, Križevci, Kuresoi, Novato, Tinajdad, Tirhert, Vicência, Wolcott), with 2174 ordinary chondrites, 130 HED achondrites, 113 carbonaceous chondrites, 41 ureilites, 27 lunar meteorites, 24 enstatite chondrites, 21 iron meteorites, 15 primitive achondrites, 11 mesosiderites, 10 Martian meteorites, 6 Rumuruti chondrites, 5 ungrouped achondrites, 2 enstatite achondrites, 1 relict meteorite, 1 pallasite, and 1 angrite, and with 1511 from Antarctica, 588 from Africa, 361 from Asia, 86 from South America, 28 from North America, and 6 from Europe. Note: 1 meteorite from Russia was counted as European. The complete contents of this bulletin (244 pages) are available on line. Information about approved meteorites can be obtained from the Meteoritical Bulletin Database (MBD) available on line at meteor/">http://www.lpi.usra.edu/meteor/.

  9. Immunogenicity and Safety of the New Inactivated Quadrivalent Influenza Vaccine Vaxigrip Tetra: Preliminary Results in Children ≥6 Months and Older Adults

    Directory of Open Access Journals (Sweden)

    Emanuele Montomoli

    2018-03-01

    Full Text Available Since the mid-1980s, two lineages of influenza B viruses have been distinguished. These can co-circulate, limiting the protection provided by inactivated trivalent influenza vaccines (TIVs. This has prompted efforts to formulate quadrivalent influenza vaccines (QIVs, to enhance protection against circulating influenza B viruses. This review describes the results obtained from seven phase III clinical trials evaluating the immunogenicity, safety, and lot-to-lot consistency of a new quadrivalent split-virion influenza vaccine (Vaxigrip Tetra® formulated by adding a second B strain to the already licensed TIV. Since Vaxigrip Tetra was developed by means of a manufacturing process strictly related to that used for TIV, the data on the safety profile of TIV are considered supportive of that of Vaxigrip Tetra. The safety and immunogenicity of Vaxigrip Tetra were similar to those of the corresponding licensed TIV. Moreover, the new vaccine elicits a superior immune response towards the additional strain, without affecting immunogenicity towards the other three strains. Vaxigrip Tetra is well tolerated, has aroused no safety concerns, and is recommended for the active immunization of individuals aged ≥6 months. In addition, preliminary data confirm its immunogenicity and safety even in children aged 6–35 months and its immunogenicity in older subjects (aged 66–80 years.

  10. Health and Safety Laboratory environmental quarterly. Final tabulation of monthly /sup 90/Sr fallout data: 1954--1976

    Energy Technology Data Exchange (ETDEWEB)

    1977-10-01

    This report presents the monthly /sup 90/Sr deposition data derived from a global network of stations started in 1954. This program was carried out to assess the distribution patterns and inventory the amount of fallout of radionuclies from atmospheric nuclear tests. In 1976, monthly deposition rates had diminished to the point where measurable levels of /sup 90/Sr were rarely observed.

  11. Bulletin of Materials Science | News

    Indian Academy of Sciences (India)

    Home; Journals; Bulletin of Materials Science; Volume 23; Issue 5. Issue front cover thumbnail. Volume 23, Issue 5. October 2000, pages 341-452. pp 341-344 Synthesis. Preparation of Pt–Ru bimetallic catalyst supported on carbon nanotubes · B Rajesh K Ravindranathan Thampi J -M Bonard B Viswanathan · More Details ...

  12. Bulletin of Materials Science | News

    Indian Academy of Sciences (India)

    Home; Journals; Bulletin of Materials Science; Volume 26; Issue 5. Issue front cover thumbnail. Volume 26, Issue 5. August 2003, pages 461-568. pp 461-464 Sensor Materials. Preparation, characterization and dielectric behaviour of some yttrium doped strontium stannates · P K Bajpai Kuldeep Ratre Mukul Pastor T P ...

  13. Bulletin of Materials Science | News

    Indian Academy of Sciences (India)

    Home; Journals; Bulletin of Materials Science; Volume 39; Issue 5. Effects of size on mass density and its influence on mechanical and thermal properties of ZrO 2 nanoparticles in different structures. BOTAN JAWDAT ABDULLAH QING JIANG MUSTAFA SAEED OMAR. Volume 39 Issue 5 September 2016 pp 1295-1302 ...

  14. Bulletin of Materials Science | News

    Indian Academy of Sciences (India)

    Home; Journals; Bulletin of Materials Science; Volume 32; Issue 4. Issue front cover thumbnail. Volume 32, Issue 4. August 2009, pages 369-463. pp 369-373 Thin Films. Mobility activation in thermally deposited CdSe thin films · Kangkan Sarmah Ranjan Sarma · More Details Abstract Fulltext PDF. Effect of illumination on ...

  15. Bulletin of Materials Science | News

    Indian Academy of Sciences (India)

    Home; Journals; Bulletin of Materials Science; Volume 40; Issue 5. Structural, microstructural and optical properties of Cu 2 ZnSnS 4 thin films prepared by thermal evaporation: effect of substrate temperature and annealing. U CHALAPATHI S UTHANNA V SUNDARA RAJA. Volume 40 Issue 5 September 2017 pp 887-895 ...

  16. Bulletin of Materials Science | News

    Indian Academy of Sciences (India)

    Home; Journals; Bulletin of Materials Science; Volume 24; Issue 1. Issue front cover thumbnail. Volume 24, Issue 1. February 2001, pages 1-94. pp 1-21 Review---Phase Transitions. Kinetics of pressure induced structural phase transitions—A review · N V Chandra Shekar K Govinda Rajan · More Details Abstract Fulltext ...

  17. Bulletin of Materials Science | News

    Indian Academy of Sciences (India)

    Home; Journals; Bulletin of Materials Science; Volume 25; Issue 6. Issue front cover thumbnail. Volume 25, Issue 6. November 2002, pages 449-582. pp 449- .... Bi-layer functionally gradient thick film semiconducting methane sensors .... Thermal sensor properties of PANI(EB)–CSA ( = 0.4 ± 0.1 mol) polymer thin films.

  18. Bulletin of Materials Science | News

    Indian Academy of Sciences (India)

    Home; Journals; Bulletin of Materials Science; Volume 30; Issue 1. Issue front cover thumbnail. Volume 30, Issue 1. February 2007, pages 1-71. pp 1-3 Single Crystals. Thermoluminescence characteristics of Sm doped NaYF4 crystals · M V Ramana Reddy Ch Gopal Reddy K Narasimha Reddy · More Details Abstract ...

  19. Bulletin of Materials Science | News

    Indian Academy of Sciences (India)

    Home; Journals; Bulletin of Materials Science; Volume 33; Issue 2 ... films deposited by rf magnetron sputtering using a high quality ceramic target ... Critical shear stress produced by interaction of edge dislocation with nanoscale inhomogeneity ... production cost limiting zircon usage as a raw material at an industrial scale.

  20. Engineering Manpower Bulletin, Number 16.

    Science.gov (United States)

    Engineers Joint Council, New York, NY. Engineering Manpower Commission.

    This bulletin presents the highlights of an evaluation of today's engineering graduates as seen by the managers of engineering, manufacturing and technical marketing in a major electrical equipment manufacturing company. Today's engineer is seen as far more productive than his predecessor. The computer has greatly expanded his productive capacity.…

  1. Bulletin of Materials Science | News

    Indian Academy of Sciences (India)

    ... Lecture Workshops · Refresher Courses · Symposia · Live Streaming. Home; Journals; Bulletin of Materials Science; Volume 36; Issue 6. Self-assembling behaviour of Pt nanoparticles onto surface of TiO2 and their resulting photocatalytic activity. M Qamar Ashok K Ganguli. Volume 36 Issue 6 November 2013 pp 945-951 ...

  2. Bulletin of Materials Science | News

    Indian Academy of Sciences (India)

    Home; Journals; Bulletin of Materials Science; Volume 32; Issue 3. Issue front cover thumbnail. Volume 32, Issue 3. June 2009, pages 215-367. pp 215-215. Foreword · S B Krupanidhi H L Bhat · More Details Fulltext PDF. pp 217-225. Molecule-based magnets · J V Yakhmi · More Details Abstract Fulltext PDF.

  3. Bulletin of Materials Science | News

    Indian Academy of Sciences (India)

    Home; Journals; Bulletin of Materials Science; Volume 40; Issue 1 ... I D S – V b g branches in accordance with the SERS results and humidity responses. ... Ni˘gde University, Graduate School Natural and Applied Sciences, Ni˘gde 51240, ...

  4. Bulletin of Materials Science | News

    Indian Academy of Sciences (India)

    Home; Journals; Bulletin of Materials Science; Volume 23; Issue 3. Issue front cover thumbnail. Volume 23, Issue 3. June 2000, pages 159-238. pp 159-163 Nanomaterials. A note on the use of ellipsometry for studying the kinetics of formation of self-assembled monolayers · Murali Sastry · More Details Abstract Fulltext PDF.

  5. Bulletin of Materials Science | News

    Indian Academy of Sciences (India)

    Home; Journals; Bulletin of Materials Science; Volume 32; Issue 2. Issue front cover thumbnail. Volume 32, Issue 2. April 2009, pages 117-214. pp 117-123 Thin Films and Nanomatter. Microstructural characteristics and mechanical properties of magnetron sputtered nanocrystalline TiN films on glass substrate.

  6. Bulletin of Materials Science | News

    Indian Academy of Sciences (India)

    Home; Journals; Bulletin of Materials Science; Volume 25; Issue 4 ... were synthesized by self-propagating high temperature synthesis (SHS) method. ... Structure determination at room temperature and phase transition studies above T c in .... Hyperfine field distributions in disordered Mn2CoSn and Mn2NiSn Heusler alloys.

  7. Bulletin of Materials Science | News

    Indian Academy of Sciences (India)

    Home; Journals; Bulletin of Materials Science; Volume 25; Issue 3 ... Sintering of nano crystalline silicon carbide by doping with boron carbide ... of these powders was achieved by addition of boron carbide of 0.5 wt% together with carbon of 1 wt% at 2050°C at vacuum (3 mbar) for 15 min. ... pp 213-217 Alloys and Steels.

  8. Proyecto Leer Bulletin, Number 11.

    Science.gov (United States)

    Tome, Martha V., Ed.

    Educational materials for students of Spanish and the Spanish speaking are listed in this bulletin. A general information section lists reference materials on bilingual children, the blind and physically handicapped, comics, consumer education, employment, health, heritage of the Spanish speaking, Mexican American biography, Mexican American film…

  9. Proyecto Leer Bulletin, Number 9.

    Science.gov (United States)

    Benson, Susan Shattuck

    This bulletin lists addresses of publishers and distributors of audiovisual instructional materials in Spanish in the United States and Latin America. Sources are listed in four categories: (1) federal sources of materials, information on materials, names of resource people, programs, and proposal guidelines concerning the Spanish speaking; (2)…

  10. Proyecto Leer Bulletin, Number 8.

    Science.gov (United States)

    Benson, Susan Shattuck

    This bulletin lists educational materials for the Spanish speaking. Several hundred documents are listed in three main sections: (1) organizations, programs, laws, and news related to the Spanish speaking; (2) a list of books selected; and (3) a list of publishers and distributors with their addresses. Several bibliographies are included. Entries…

  11. Proyecto Leer Bulletin, Number 12.

    Science.gov (United States)

    Tome, Martha V., Ed.

    This bulletin is designed to serve the Spanish-speaking population of the United States. This issue contains a list of popular magazines in Spanish for children and adults. Another section provides the names of comics for children. Titles to be found under "Publications in Series and Collections" are the popular type of romantic, western, or…

  12. Bulletin of Materials Science | News

    Indian Academy of Sciences (India)

    Home; Journals; Bulletin of Materials Science; Volume 38; Issue 3 .... (EDX) and UV–vis spectroscopy were used to study the chemical composition and optical .... Enhanced microactuation with magnetic field curing of magnetorheological ... Structure, morphology and corrosion resistance of Ni–Mo+PTh composite coatings.

  13. The Bulletin turns the page

    CERN Multimedia

    2006-01-01

    Today, the paper version of the CERN Bulletin has a new look, the first since the 1970s. The new layout, which has been designed to improve readability, is part of an ongoing effort to improve internal communication at CERN. The Bulletin is the Organization's main tool for communication with the CERN community. It keeps everyone abreast of information that is important and essential for our working life at CERN. It plays an important role in keeping us up to date with social and scientific developments at the Laboratory. And it should be a force for cohesion across this very diverse organization. At the same time, the distribution for the printed Bulletin is being changed from individual mailboxes to distribution points around the Laboratory. This reflects changing reading habits, with the on-line version gaining a steadily increasing readership. For some time now, the paper Bulletin has been published fortnightly. However, the on-line version is updated weekly, so I encourage you all to look at it. In addi...

  14. Bulletin of Materials Science | News

    Indian Academy of Sciences (India)

    Home; Journals; Bulletin of Materials Science; Volume 27; Issue 4. Issue front cover thumbnail. Volume 27, Issue 4. August 2004, pages 323-394. pp 323-325 Crystal Growth. Growth features of ammonium hydrogen -tartrate single crystals · G Sajeevkumar R Raveendran B S Remadevi Alexander Varghese Vaidyan.

  15. Bulletin of Materials Science | News

    Indian Academy of Sciences (India)

    Home; Journals; Bulletin of Materials Science; Volume 29; Issue 1. Issue front cover thumbnail. Volume 29, Issue 1. February 2006, pages 1-99. pp 1-5 Nanomaterials. A simple synthesis and characterization of CuS nanocrystals · Ujjal K Gautam Bratindranath Mukherjee · More Details Abstract Fulltext PDF. Water-soluble ...

  16. BJPsych Bulletin author mentoring scheme - helping trainees become published authors.

    Science.gov (United States)

    Pimm, Jonathan; Galbraith, Niall

    2016-02-01

    The publishing world is changing rapidly. Innovations include the move to open access, the rise of social media and the transition to digitalisation. In the light of these developments and with ever-increasing pressures on early career psychiatrists and trainees to publish papers in journals with a recognised pedigree, the BJPsych Bulletin is piloting an author mentoring scheme. Mentors will help clinicians and aspiring academics develop articles from a pedestrian manuscript to one that will hopefully provoke important debate and aid changes in current practices. The scheme will run on a trial basis for approximately 12 months and will then be reviewed. Mentoring has been found to have an important effect of research output including publication and grant success; the hope is that this new initiative at the BJPsych Bulletin will result in such dividends to all involved.

  17. Safety of the malaria vaccine candidate, RTS,S/AS01E in 5 to 17 month old Kenyan and Tanzanian Children.

    Directory of Open Access Journals (Sweden)

    John Lusingu

    2010-11-01

    Full Text Available The malaria vaccine candidate, RTS,S/AS01(E, showed promising protective efficacy in a trial of Kenyan and Tanzanian children aged 5 to 17 months. Here we report on the vaccine's safety and tolerability. The experimental design was a Phase 2b, two-centre, double-blind (observer- and participant-blind, randomised (1∶1 ratio controlled trial. Three doses of study or control (rabies vaccines were administered intramuscularly at 1 month intervals. Solicited adverse events (AEs were collected for 7 days after each vaccination. There was surveillance and reporting for unsolicited adverse events for 30 days after each vaccination. Serious adverse events (SAEs were recorded throughout the study period which lasted for 14 months after dose 1 in Korogwe, Tanzania and an average of 18 months post-dose 1 in Kilifi, Kenya. Blood samples for safety monitoring of haematological, renal and hepatic functions were taken at baseline, 3, 10 and 14 months after dose 1. A total of 894 children received RTS,S/AS01(E or rabies vaccine between March and August 2007. Overall, children vaccinated with RTS,S/AS01(E had fewer SAEs (51/447 than children in the control group (88/447. One SAE episode in a RTS,S/AS01(E recipient and nine episodes among eight rabies vaccine recipients met the criteria for severe malaria. Unsolicited AEs were reported in 78% of subjects in the RTS,S/AS01(E group and 74% of subjects in the rabies vaccine group. In both vaccine groups, gastroenteritis and pneumonia were the most frequently reported unsolicited AE. Fever was the most frequently observed solicited AE and was recorded after 11% of RTS,S/AS01(E doses compared to 31% of doses of rabies vaccine. The candidate vaccine RTS,S/AS01(E showed an acceptable safety profile in children living in a malaria-endemic area in East Africa. More data on the safety of RTS,S/AS01(E will become available from the Phase 3 programme.

  18. Safety

    International Nuclear Information System (INIS)

    1998-01-01

    A brief account of activities carried out by the Nuclear power plants Jaslovske Bohunice in 1997 is presented. These activities are reported under the headings: (1) Nuclear safety; (2) Industrial and health safety; (3) Radiation safety; and Fire protection

  19. Don't miss the Announcements and Events sections of the Bulletin!

    CERN Multimedia

    2014-01-01

    There you'll find information on the new EDMS, the 37th CERN School of Computing, the Safety Bulletin 2014-2, the opening times for CERN restaurants over the Easter weekend, the 2014 Asia-Europe-Pacific School of High-Energy Physics, the Diversity in Action Workshop, the Raspberry Pi programming day... this information is FOR YOU!

  20. Fire and the Design of Educational Buildings. Building Bulletin 7. Sixth Edition.

    Science.gov (United States)

    Department of Education and Science, London (England).

    This bulletin offers guidance on English school premises regulations applying to safety protection against fires in the following general areas: means of escape in case of fire; precautionary measures to prevent fire; fire warning systems and fire fighting; fire spreading speed; structures and materials resistant to fires; and damage control. It…

  1. Efficacy and Safety of the RTS,S/AS01 Malaria Vaccine during 18 Months after Vaccination

    DEFF Research Database (Denmark)

    Theander, Thor Grundtvig; Lusingu, John Peter Andrea

    2014-01-01

    BACKGROUND: A malaria vaccine could be an important addition to current control strategies. We report the safety and vaccine efficacy (VE) of the RTS,S/AS01 vaccine during 18 mo following vaccination at 11 African sites with varying malaria transmission. METHODS AND FINDINGS: 6,537 infants aged 6......-12 wk and 8,923 children aged 5-17 mo were randomized to receive three doses of RTS,S/AS01 or comparator vaccine. VE against clinical malaria in children during the 18 mo after vaccine dose 3 (per protocol) was 46% (95% CI 42% to 50%) (range 40% to 77%; VE, p... after vaccine dose 1 (intention to treat [ITT]) was 45% (95% CI 41% to 49%). VE against severe malaria, malaria hospitalization, and all-cause hospitalization was 34% (95% CI 15% to 48%), 41% (95% CI 30% to 50%), and 19% (95% CI 11% to 27%), respectively (ITT). VE against clinical malaria in infants...

  2. Gap Analysis Bulletin No. 13

    Science.gov (United States)

    2005-12-01

    we would like to web developer; gather comments from GAP researchers and data users. We are * facilitate collaboration among GAP projects by...N.Y. Research Grant #012/01 A. 42 Gap Analysis Bulletin No. 13, December 2005 Ga pAnalysis Smith, S. D., W. A. Brown, C. R. Smith, and M. E. Richmond... GAP will be focusing activities have greatly reduced the habitat available to support on the enduring features of the Great Lakes basin. Influences

  3. Practice Bulletin Summary No. 152: Emergency Contraception.

    Science.gov (United States)

    2015-09-01

    Emergency contraception, also known as postcoital contraception, is therapy used to prevent pregnancy after an unprotected or inadequately protected act of sexual intercourse. Common indications for emergency contraception include contraceptive failure (eg, condom breakage or missed doses of oral contraceptives) and failure to use any form of contraception (1-3). Although oral emergency contraception was first described in the medical literature in the 1960s, the U.S. Food and Drug Administration (FDA) approved the first dedicated product for emergency contraception in 1998. Since then, several new products have been introduced. Methods of emergency contraception include oral administration of combined estrogen-progestin, progestin only, or selective progesterone receptor modulators and insertion of a copper intrauterine device (IUD). Many women are unaware of the existence of emergency contraception, misunderstand its use and safety, or do not use it when a need arises (4-6). The purpose of this Practice Bulletin is to review the evidence for the efficacy and safety of available methods of emergency contraception and to increase awareness of these methods among obstetrician-gynecologists and other gynecologic providers.

  4. Practice Bulletin No. 152: Emergency Contraception.

    Science.gov (United States)

    2015-09-01

    Emergency contraception, also known as postcoital contraception, is therapy used to prevent pregnancy after an unprotected or inadequately protected act of sexual intercourse. Common indications for emergency contraception include contraceptive failure (eg, condom breakage or missed doses of oral contraceptives) and failure to use any form of contraception (). Although oral emergency contraception was first described in the medical literature in the 1960s, the U.S. Food and Drug Administration (FDA) approved the first dedicated product for emergency contraception in 1998. Since then, several new products have been introduced. Methods of emergency contraception include oral administration of combined estrogen-progestin, progestin only, or selective progesterone receptor modulators and insertion of a copper intrauterine device (IUD). Many women are unaware of the existence of emergency contraception, misunderstand its use and safety, or do not use it when a need arises (). The purpose of this Practice Bulletin is to review the evidence for the efficacy and safety of available methods of emergency contraception and to increase awareness of these methods among obstetrician-gynecologists and other gynecologic providers.

  5. Fukushima-Dai-Ichi accident. Information bulletin no. 6 from June 8, 2011

    International Nuclear Information System (INIS)

    2011-01-01

    This news bulletin has been prepared by the French institute of radiation protection and nuclear safety (IRSN) for the information of French residents in Japan. It presents, first, the situation at the date of the bulletin of the radioactive contamination in the provinces close to the Fukushima Dai-ichi damaged site, the follow-up of the commercialisation restrictions of some food products (vegetables, mushrooms, milk). Then, it gives some general recommendations to residents concerning good food consumption practices and supplies a list of particularly impacted areas where it is to be highly avoided to travel to. (J.S.)

  6. Fukushima-Daiichi accident. News bulletin no. 1 from April 6

    International Nuclear Information System (INIS)

    2011-01-01

    This news bulletin has been prepared by the French institute of radiation protection and nuclear safety (IRSN) for the information of French residents in Japan. It presents, first, the situation at the date of the bulletin of the reactors at the power plant site, the accident management actions in progress, the radioactive contamination around the site and the meteorological forecasts. Then, it gives some general recommendations to residents concerning food consumption and dwelling hygiene. Finally, some scientific information about radionuclides migration, radioactive pollution and their environmental impact are given. (J.S.)

  7. Fukushima-Dai-Ichi accident. Information bulletin no. 8 from December 12, 2011

    International Nuclear Information System (INIS)

    2011-01-01

    This news bulletin has been prepared by the French institute of radiation protection and nuclear safety (IRSN) for the information of French residents in Japan. It presents, first, the situation at the date of the bulletin of the food chain contamination in the provinces close to the Fukushima Dai-ichi damaged site, the particular case of rice contamination monitoring and the controls performed at retailer shops. Then, it gives some general recommendations to residents concerning good food consumption and hygiene practices and recommends to avoid any unnecessary travel to the most impacted areas close to the prohibited access area. (J.S.)

  8. Safety and Immunogenicity of Full-Dose Trivalent Inactivated Influenza Vaccine (TIV) Compared With Half-Dose TIV Administered to Children 6 Through 35 Months of Age.

    Science.gov (United States)

    Halasa, Natasha B; Gerber, Michael A; Berry, Andrea A; Anderson, Edwin L; Winokur, Patricia; Keyserling, Harry; Eckard, Allison Ross; Hill, Heather; Wolff, Mark C; McNeal, Monica M; Edwards, Kathryn M; Bernstein, David I

    2015-09-01

    Children 6 through 35 months of age are recommended to receive half the dose of influenza vaccine compared with older children and adults. This was a 6-site, randomized 2:1, double-blind study comparing full-dose (0.5 mL) trivalent inactivated influenza vaccine (TIV) with half-dose (0.25 mL) TIV in children 6 through 35 months of age. Children previously immunized with influenza vaccine (primed cohort) received 1 dose, and those with no previous influenza immunizations (naive cohort) received 2 doses of TIV. Local and systemic adverse events were recorded. Sera were collected before immunization and 1 month after last dose of TIV. Hemagglutination inhibition antibody testing was performed. Of the 243 subjects enrolled (32 primed, 211 naive), data for 232 were available for complete analysis. No significant differences in local or systemic reactions were observed. Few significant differences in immunogenicity to the 3 vaccine antigens were noted. The immune response to H1N1 was significantly higher in the full-dose group among primed subjects. In the naive cohort, the geometric mean titer for all 3 antigens after 2 doses of TIV were significantly higher in the 12 through 35 months compared with the 6 through 11 months age group. Our study confirms the safety of full-dose TIV given to children 6 through 35 months of age. An increase in antibody responses after full- versus half-dose TIV was not observed, except for H1N1 in the primed group. Larger studies are needed to clarify the potential for improved immunogenicity with higher vaccine doses. Recommending the same dose could simplify the production, storage, and administration of influenza vaccines.

  9. ICFA Instrumentation Bulletin, Volume 14, Spring 1997

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1997-07-01

    The publication of the ICFA Instrumentation Bulletin is an activity of the Panel on Future Innovation and Development of ICFA (International Committee for Future Accelerators). The Bulletin reports on research and progress in the field of instrumentation with emphasis on application in the field of high-energy physics. It encourages issues of generic instrumentation.

  10. OCRWM Bulletin, summer/fall 1994

    International Nuclear Information System (INIS)

    1994-01-01

    This publication consists of two parts, OCRWM Bulletin, and Of Mountains ampersand Science which is about the Yucca Mountain project. The OCRWM bulletin provides information about OCRWM activities, program update to Congress, reorganization, training provided on OCRWM database, OCRWM calendar, and exhibit schedule for 1994. Recent work at the Yucca Mountain project such as the tunnel boring machines are presented in layman's term

  11. 1991 OCRWM bulletin compilation and index

    International Nuclear Information System (INIS)

    1992-05-01

    The OCRWM Bulletin is published by the Department of Energy, Office of Civilian Radioactive Waste Management, to provide current information about the national program for managing spent fuel and high-level radioactive waste. The document is a compilation of issues from the 1991 calendar year. A table of contents and an index have been provided to reference information contained in this year's Bulletins

  12. Primary (Month-6) Outcomes of the STOP-Uveitis Study: Evaluating the Safety, Tolerability, and Efficacy of Tocilizumab in Patients With Noninfectious Uveitis.

    Science.gov (United States)

    Sepah, Yasir Jamal; Sadiq, Mohammad Ali; Chu, David S; Dacey, Mark; Gallemore, Ron; Dayani, Pouya; Hanout, Mostafa; Hassan, Muhammad; Afridi, Rubbia; Agarwal, Aniruddha; Halim, Muhammad Sohail; Do, Diana V; Nguyen, Quan Dong

    2017-11-01

    To report the primary endpoint analyses of the safety and efficacy of 2 different doses of intravenous (IV) infusions of tocilizumab (TCZ), an IL-6 inhibitor, in eyes with noninfectious intermediate uveitis, posterior uveitis, or panuveitis. Randomized, controlled, multicenter clinical trial. STOP-Uveitis is a randomized, open-label safety, efficacy, and bioactivity clinical trial conducted at 5 clinical centers across the United States. The study evaluated the role of TCZ in patients with noninfectious uveitis (NIU). Thirty-seven patients with NIU were randomized into one of 2 treatment groups in a ratio of 1:1. Group 1 received IV infusions of 4 mg/kg TCZ and group 2 received IV infusions of 8 mg/kg TCZ. Infusions were given every 4 weeks in both groups until month 6 (primary endpoint). Primary outcome measure was incidence and severity of systemic and ocular adverse events through month 6. Secondary outcome measures included mean change in visual acuity (VA), vitreous haze (VH), and central macular thickness (CMT) at month 6. A total of 37 patients were randomized in the study. At month 6, 43.5% of patients who had the potential for a 2-step decrease in VH demonstrated a 2-step decrease (40% in Group 1 and 46.1% in Group 2). Mean change in CMT was -83.88 ± 136.1 μm at month 6 (-131.5 ± 41.56 μm in Group 1 and -38.92 ± 13.7 μm in Group 2). Mean change in VA was +8.22 ± 11.83 ETDRS letters at month 6 (10.9 ± 14.6 in Group 1 and 5.5 ± 7.8 in Group 2). Repeated infusions of TCZ were well tolerated. Repeated IV administrations of TCZ are well tolerated. TCZ (both 4 and 8 mg/kg) is effective in improving VA and reducing VH and CMT in eyes with noninfectious intermediate uveitis, posterior uveitis, and panuveitis. Copyright © 2017 Elsevier Inc. All rights reserved.

  13. Nuclear Law Bulletin No. 96. Volume 2015/2

    International Nuclear Information System (INIS)

    Reynolds, M.; Thiele, L.; Touitou-Durand, F.; Pelzer, N.; Tafili, V.; Manually, Y.; Adomaityte, U.; Adamczyk, K.; Nowacki, T.; Chiripus, V.; Pistekova, Z.; Skraban, A.; Knopp Pisi, S.; Hoang, V.; Rothschild, T.; Durand, A.; Rivera, S.R.; Salter, I.

    2015-01-01

    The Nuclear Law Bulletin is a unique international publication for both professionals and academics in the field of nuclear law. It provides readers with authoritative and comprehensive information on nuclear law developments. Published free online twice a year in both English and French, it features topical articles written by renowned legal experts, covers legislative developments worldwide and reports on relevant case law, bilateral and international agreements as well as regulatory activities of international organisations. Feature articles in this issue include 'Treaty implementation applied to conventions on nuclear safety' and 'Crisis, criticism, change: Regulatory reform in the wake of nuclear accidents'. (authors)

  14. Retrospective Analysis on the Efficacy, Safety and Treatment Failure Group of Sitagliptin for Mean 10-Month Duration

    Directory of Open Access Journals (Sweden)

    Won Jun Kim

    2011-06-01

    Full Text Available BackgroundTo investigate the clinical results of sitagliptin (SITA and the characteristics of the treatment failure group or of low responders to SITA.MethodsA retrospective study of type 2 diabetic patients reviewed 99 cases, including 12 treatment failure cases, who stopped SITA because of worsening patients' condition, and 87 cases, who continued treatment over five visits (total 9.9±10.1 months after receiving the prescription of SITA from December 2008 to June 2009. Subjects were classified as five groups administered SITA as an initial combination with metformin (MET, add-on to metformin or sulfonylurea, and switching from sulfonylurea or thiazolidinedione. The changes in HbA1c level from the first to last visit (ΔHbA1c in treatment maintenance group were subanalyzed.ResultsThe HbA1c level was significantly reduced in four groups, including initial coadministration of SITA with metformin (ΔHbA1c=-1.1%, P<0.001, add-on to MET (ΔHbA1c=-0.6%, P=0.017, add-on to sulfonylurea (ΔHbA1c=-0.5%, P<0.001, and switching from thiazolidinedione (ΔHbA1c=-0.3%, P=0.013. SITA was noninferior to sulfonlyurea (ΔHbA1c=-0.2%, P=0.63. There was no significant adverse effect. The treatment failure group had a longer diabeties duration (P=0.008, higher HbA1c (P=0.001 and fasting plasma glucose (P=0.003 compared to the maintenance group. Subanalysis on the tertiles of ΔHbA1c showed that low-response to SITA (tertile 1 was associated with a longer diabetes duration (P=0.009 and lower HbA1c (P<0.001.ConclusionSITA was effective and safe for use in Korean type 2 diabetic patients. However, its clinical responses and long-term benefit-harm profile is yet to be established.

  15. Communication from the Safety Service

    CERN Multimedia

    DG Unit - General Safety

    In any emergency, you should call 74444 (+41 22 76 74444). There is something that bears repeating - especially in the light of recent events. The new Safety Bulletin, No. 2009-01, reminds us that, although raising the alarm and giving first aid in an emergency are everyone’s job, “medical transport is a job for professionals.” You are urged to read, print and share the Safety Bulletin No. 2009-01: remember for all emergencies you should dial 74444! We appreciate your comments and suggestions. Write to safety-general@cern.ch.

  16. Metformin effectiveness and safety in the management of overweight/obese nondiabetic children and adolescents: metabolic benefits of the continuous exposure to metformin at 12 and 24 months.

    Science.gov (United States)

    Marques, Pedro; Limbert, Catarina; Oliveira, Laura; Santos, Maria Inês; Lopes, Lurdes

    2016-02-19

    Childhood obesity prevalence is rising and new therapeutical approaches are needed. Metformin is likely beneficial in obese and/or insulin-resistant children/adolescents, but its role in this setting is still unclear. We aimed to evaluate the effectiveness, in terms of weight loss and insulin resistance, and safety of metformin in nondiabetic overweight/obese children and adolescents. We retrospectively reviewed clinical records of 78 nondiabetic obese/overweight [body mass index (BMI)≥85th/95th percentile for age and sex] children and adolescents. Anthropometric and metabolic outcomes of 39 patients treated with metformin (mean daily dose: 1.3±0.5 g) were analyzed and compared to lifestyle intervention alone at different follow-up times (12 and 24 months). The mean age of the 78 patients was 13.3 years, 41 were females and mean BMI and BMI-SDS were 32.8 kg/m2 and 3.1, respectively. There was a decrease in mean BMI-SDS within each treatment group in all periods, except at 24 months for lifestyle intervention. However, the change in BMI-SDS was not significantly superior in the metformin group when compared to lifestyle intervention. Metformin had greater effectiveness over lifestyle intervention alone in reducing fasting insulin levels and homeostasis model assessment for insulin-resistance index (HOMA-IR) at both 12 and 24 months. Five patients had gastrointestinal adverse effects (12.8%), four requiring dose reduction, but metformin could be resumed in all. Metformin for nondiabetic obese/overweight children and adolescents resulted in a noteworthy insulin resistance improvement, without significant BMI advantage when compared to lifestyle intervention. Metformin metabolic and anthropometric effects appear to be beneficial up to 24 months, without relevant adverse effects, highlighting its potential long-term benefits.

  17. SAFETY

    CERN Multimedia

    Niels Dupont

    2013-01-01

    CERN Safety rules and Radiation Protection at CMS The CERN Safety rules are defined by the Occupational Health & Safety and Environmental Protection Unit (HSE Unit), CERN’s institutional authority and central Safety organ attached to the Director General. In particular the Radiation Protection group (DGS-RP1) ensures that personnel on the CERN sites and the public are protected from potentially harmful effects of ionising radiation linked to CERN activities. The RP Group fulfils its mandate in collaboration with the CERN departments owning or operating sources of ionising radiation and having the responsibility for Radiation Safety of these sources. The specific responsibilities concerning "Radiation Safety" and "Radiation Protection" are delegated as follows: Radiation Safety is the responsibility of every CERN Department owning radiation sources or using radiation sources put at its disposition. These Departments are in charge of implementing the requi...

  18. Discontinuation of the Bulletin's menu page

    CERN Document Server

    Publications Section

    2005-01-01

    The menus of the various CERN restaurants will no longer be published in the Bulletin as of Monday 4 April (issue No. 14/2005). The menu pages are being discontinued both as a savings measure and due to the low level of interest in this section of the Bulletin. The most recent survey of Bulletin readers showed that only 13% of the people questioned regularly read the menu section, compared to between 40% and 85% in the case of the other sections. Publications Section SG/CO Tel. 79971

  19. Discontinuation of the Bulletin's menu page

    CERN Multimedia

    Publications Section

    2005-01-01

    The menus of the various CERN restaurants will no longer be published in the Bulletin as of Monday 4 April (issue No. 14/2005). The menu pages are being discontinued both as a savings measure and due to the low level of interest in this section of the Bulletin. The most recent survey of Bulletin readers showed that only 13% of the people questioned regularly read the menu section, compared to between 40% and 85% in the case of the other sections. Publications Section DSU-CO Tel. 79971

  20. Safety data on 19 vehicles for use in 1 month oral rodent pre-clinical studies: administration of hydroxypropyl-ß-cyclodextrin causes renal toxicity.

    Science.gov (United States)

    Healing, Guy; Sulemann, Tabassum; Cotton, Peter; Harris, Jayne; Hargreaves, Adam; Finney, Rowena; Kirk, Sarah; Schramm, Carolin; Garner, Clare; Pivette, Perrine; Burdett, Lisa

    2016-01-01

    Potential new drugs are assessed in pre-clinical in vivo studies to determine their safety profiles. The drugs are formulated in vehicles suitable for the route of administration and the physicochemical properties of the drug, aiming to achieve optimal exposure in the test species. The availability of safety data on vehicles is often limited (incomplete data, access restricted/private databases). Nineteen potentially useful vehicles that contained new and/or increased concentrations of excipients and for which little safety data have been published were tested. Vehicles were dosed orally once daily to HanWistar rats for a minimum of 28 days and a wide range of toxicological parameters were assessed. Only 30% (w/v) hydroxypropyl-ß-cyclodextrin was found unsuitable owing to effects on liver enzymes (AST, ALT and GLDH), urinary volume and the kidneys (tubular vacuolation and tubular pigment). 20% (v/v) oleic acid caused increased salivation and hence this vehicle should be used with caution. As 40% (v/v) tetraethylene glycol affected urinary parameters, its use should be carefully considered, particularly for compounds suspected to impact the renal system and studies longer than 1 month. There were no toxicologically significant findings with 10% (v/v) dimethyl sulphoxide, 20% (v/v) propylene glycol, 33% (v/v) Miglyol®812, 20% (w/v) Kolliphor®RH40, 10% (w/v) Poloxamer 407, 5% (w/v) polyvinylpyrrolidone K30 or 10% (v/v) Labrafil®M1944. All other vehicles tested caused isolated or low magnitude effects which would not prevent their use. The aim of sharing these data, including adverse findings, is to provide meaningful information for vehicle selection, thereby avoiding repetition of animal experimentation. Copyright © 2015 John Wiley & Sons, Ltd.

  1. Safety

    International Nuclear Information System (INIS)

    2001-01-01

    This annual report of the Senior Inspector for the Nuclear Safety, analyses the nuclear safety at EDF for the year 1999 and proposes twelve subjects of consideration to progress. Five technical documents are also provided and discussed concerning the nuclear power plants maintenance and safety (thermal fatigue, vibration fatigue, assisted control and instrumentation of the N4 bearing, 1300 MW reactors containment and time of life of power plants). (A.L.B.)

  2. Annual market and own load bulletin - 1992

    International Nuclear Information System (INIS)

    1993-01-01

    This bulletin makes the market analysis for electric energy in Brazil in 1992, presenting data about energy consumption in each Brazilian region and the prices of electric power and petroleum products. (M.V.M.)

  3. Safety and immunogenicity of a live attenuated RSV vaccine in healthy RSV-seronegative children 5 to 24 months of age.

    Directory of Open Access Journals (Sweden)

    Elissa Malkin

    Full Text Available Despite substantial morbidity associated with respiratory syncytial virus (RSV infection, there is no licensed vaccine. MEDI-559 is a live attenuated intranasal vaccine candidate being developed for prevention of lower respiratory illness due to RSV in young children. This randomized, placebo-controlled study evaluated safety of MEDI-559 in healthy, RSV-seronegative children. MEDI-559 or placebo was administered on 3 occasions, 2 months apart. Primary safety was based on solicited symptoms (SSs and adverse events (AEs collected for 28 days after each dose. Nasal wash samples were collected 3 times after each dose (days 7-10, 12-18, 28-34 and at sick visits. Serum was collected for measuring antibody immune responses to RSV prior to first vaccination and 28 days post final dose. Long-term safety was monitored for 365 days from first dose. SSs were mild and frequent (MEDI-559 84%; placebo 91%; most common SSs were runny/stuffy nose, cough, and irritability/fussiness. AEs occurred in 67% MEDI-559 and 57% placebo recipients: most common AE was upper respiratory tract infection (MEDI-559 35%; placebo 23%. Higher incidence of medically attended lower respiratory illness within 28 days after dosing occurred in the MEDI-559 arm compared to placebo (none associated with vaccine virus shedding. There was no evidence of enhanced RSV disease. Vaccine virus was detected only in MEDI-559 recipients; shedding occurred in 56%subjects, primarily post dose 1. A functional immune response was observed in 59% and 9% MEDI-559 and placebo recipients, respectively, by an RSV microneutralization assay. Vaccine take, assessed by proportion that shed vaccine-type virus or had a seroresponse against RSV, was seen in 95% MEDI-559 subjects. MEDI-559 is therefore biologically active and immunogenic in this seronegative pediatric population. Although the frequency of SSs and AEs was not considered clinically significant, the increase in medically attended lower respiratory

  4. CAT-ASVAB Technical Bulletin Number 1

    Science.gov (United States)

    2006-03-01

    CAT -ASVAB Technical Bulletin #1 Personnel Testing Division Defense Manpower Data Center March 2006 Report...2. REPORT TYPE N/A 3. DATES COVERED - 4. TITLE AND SUBTITLE CAT -ASVAB Technical Bulletin #1 5a. CONTRACT NUMBER 5b. GRANT NUMBER 5c...Hetter, R. D. "Psychometric Procedures for Administering CAT -ASVAB" (pp. 131-140) Chapter 4 Hetter, R. D., & Sympson J. B. "Item Exposure

  5. NEW EDITOR OF THE CMS BULLETIN

    CERN Multimedia

    Walter Van Doninck has been the Editor of the CMS Bulletin since 2000. The Bulletin not only helps disseminate information but also records the progress of CMS. Walter is handing over to Karl Gill. We would like to thank Walter for carrying out this task with enthusiasm and efficiency for so long. We should also thank Karl for accepting to take over and wish him well over the coming exciting period.

  6. The new Bulletin arrives in two weeks

    CERN Multimedia

    2006-01-01

    In May, you will discover a redesigned CERN Bulletin. Starting with the first May issue (No. 19-20/2006), the format of the CERN Bulletin will change completely. The page layout will be more attractive, reminiscent of a proper newspaper, with pictograms to identify the different sections. The information provided will also be more visible. The Bulletin was much in need of a makeover as its current layout dates back to 1976! The introduction of the new format will coincide with the introduction of a new means of distribution. You will still receive the elctronic version of the Bulletin every week directly on your computer. However, in order to avoid the waste from the dozens of copies that linger unread in people's mailboxes, the paper version will be available at a series of distribution points around the Laboratory. You will find the Bulletin along with the Staff Association newsletter at the cafeteria closest to your office. The Bulletin will be available from the following distribution points: On the M...

  7. The redesigned Bulletin is on its way

    CERN Multimedia

    2006-01-01

    In May, you will discover a redesigned CERN Bulletin. Starting with the first May issue (No. 19-20/2006), the format of the Bulletin will change completely. The page layout will be more attractive, reminiscent of a proper newspaper, with pictograms to identify the different sections. The information provided will also be more visible. The Bulletin was much in need of a makeover as its current layout dates back to 1976! The introduction of the new format will coincide with the introduction of a new means of distribution. You will still receive the electronic version of the Bulletin every week directly on your computer. However, in order to avoid the waste from the dozens of copies that linger unread in people's mailboxes, the paper version will be available at a series of distribution points around the Laboratory. You will find the Bulletin along with the Staff Association newsletter at the cafeteria closest to your office. The Bulletin will be available from the following distribution points: On the Meyrin...

  8. Bulletin of the Research Laboratory for Nuclear Reactors

    International Nuclear Information System (INIS)

    Aritomi, Masanori

    2008-01-01

    The bulletin consists of two parts. The first part includes General Research Report. The Research Laboratory for Nuclear Reactors, Tokyo Institute of Technology has three engineering divisions such as Energy Engineering, Mass Transmutation Engineering, and System and Safety Engineering. In this part, 17 reports of Energy Engineering division, 8 reports of Mass transmutation Engineering division, 11 reports of System and Safety Engineering division are described as their activities. In addition, 3 reports of Cooperative Researches are also summarized. The second part is Special Issue about COE-INES RESEARCH REPORT 2007. In this part, 3 reports of Innovative Reactor Group, 2 reports of Innovative Nuclear Energy Utilization System Group, 3 reports of Innovative Transmutation/Separation Group, 2 reports of Relationship between Nuclear and Society Group, 1 report of RA Students in the COE-INES Captainship Educational Program are described as results to their researches. (J.P.N.)

  9. 75 FR 14243 - Pipeline Safety: Girth Weld Quality Issues Due to Improper Transitioning, Misalignment, and...

    Science.gov (United States)

    2010-03-24

    ... DEPARTMENT OF TRANSPORTATION Pipeline and Hazardous Materials Safety Administration [Docket No..., and Welding Practices of Large Diameter Line Pipe AGENCY: Pipeline and Hazardous Materials Safety... bulletin to notify owners and operators of recently constructed large diameter natural gas pipeline and...

  10. 75 FR 22678 - Pipeline Safety: Implementation of Electronic Filing for Recently Revised Incident/Accident...

    Science.gov (United States)

    2010-04-29

    ... DEPARTMENT OF TRANSPORTATION Pipeline and Hazardous Materials Safety Administration [Docket No... Liquid Systems AGENCY: Pipeline and Hazardous Materials Safety Administration (PHMSA), DOT. ACTION: Notice; Issuance of Advisory Bulletin. SUMMARY: This notice advises owners and operators of gas pipeline...

  11. Safety and efficacy of pregabalin in adolescents with fibromyalgia: a randomized, double-blind, placebo-controlled trial and a 6-month open-label extension study.

    Science.gov (United States)

    Arnold, Lesley M; Schikler, Kenneth N; Bateman, Lucinda; Khan, Tahira; Pauer, Lynne; Bhadra-Brown, Pritha; Clair, Andrew; Chew, Marci L; Scavone, Joseph

    2016-07-30

    Fibromyalgia (FM) is a common pain condition characterized by widespread musculoskeletal pain and tenderness. Pregabalin is an approved treatment for adults in the United States, but there are no approved treatments for adolescents with FM. This was a 15-week, randomized, double-blind, placebo-controlled study and 6-month open-label safety trial of flexible-dose pregabalin (75-450 mg/day) for the treatment of adolescents (12-17 years) with FM. Primary outcome was change in mean pain score at endpoint (scored from 0-10, with 24-h recall). Secondary outcomes included global assessments and measures of pain, sleep, and FM impact. A total of 107 subjects were randomized to treatment (54 pregabalin, 53 placebo) and 80 completed the study (44 pregabalin, 36 placebo). Improvement in mean pain score at endpoint with pregabalin versus placebo was not statistically significant, treatment difference (95 % CI), -0.66 (-1.51, 0.18), P = 0.121. There were significant improvements with pregabalin versus placebo in secondary outcomes of change in pain score by week (P recall), treatment difference (95 % CI), -0.87 (-1.68, -0.05), P = 0.037; and patient global impression of change, 53.1 % versus 29.5 % very much or much improved (P = 0.013). Trends toward improvement with pregabalin in other secondary outcomes measuring pain, sleep, and FM impact were not significant. Safety was consistent with the known profile of pregabalin in adults with FM. Pregabalin did not significantly improve the mean pain score in adolescents with FM. There were significant improvements in secondary outcomes measuring pain and impression of change. NCT01020474 ; NCT01020526 .

  12. Medical Surveillance Monthly Report

    Science.gov (United States)

    2016-12-01

    Illness Prevention and Sun Safety. “Sun Safety.” https:// phc.amedd.army.mil/ topics /discond/hipss/Pages/ SunSafety.aspx. Accessed on 7 December 2016. 22...febrile illness; however, after its wide- spread introduction into immunologically MSMR Vol. 23 No. 12 December 2016 Page 8 naïve populations, a...October 2016 (data as of 22 November 2016) MSMR’s Invitation to Readers Medical Surveillance Monthly Report (MSMR) invites readers to submit topics for

  13. Bulletin of Animal Health and Production in Africa: Journal ...

    African Journals Online (AJOL)

    Bulletin of Animal Health and Production in Africa: Journal Sponsorship. Journal Home > About the Journal > Bulletin of Animal Health and Production in Africa: Journal Sponsorship. Log in or Register to get access to full text downloads.

  14. Safety and Efficacy of Atazanavir Powder and Ritonavir in HIV-1-Infected Infants and Children From 3 Months to The PRINCE-2 Study.

    Science.gov (United States)

    Cotton, Mark F; Liberty, Afaaf; Torres-Escobar, Indiana; Gonzalez-Tome, Maria Isabel; Lissens, Jurgen; Zaru, Luna; Klauck, Isabelle; Cambilargiu, Daniela; Pikora, Cheryl; Correll, Todd A

    2018-06-01

    Novel antiretroviral formulations that are palatable, safe, and effective are needed for infants and children. PRINCE-2 is an ongoing clinical trial assessing safety, efficacy, and palatability of once-daily atazanavir powder formulation boosted with ritonavir (ATV + RTV) plus optimized dual nucleos(t)ide reverse transcriptase inhibitors therapy in antiretroviral-naïve/experienced children with screening HIV-1 RNA ≥1000 copies/mL. Children 3 months to <11 years received ATV + RTV by 5 baseline weight bands: 5 to <10 kg = 150/80 mg; 5 to <10 kg = 200/80 mg; 10 to <15 kg = 200/80 mg; 15 to <25 kg = 250/80 mg; and 25 to <35 kg = 300/100 mg. Of 99 treated children, 83.8% and 59.6% remained on ATV powder until 24 and 48 weeks, respectively. Through 48 weeks, the most common adverse events were upper respiratory tract infections (33.3%), gastroenteritis (28.3%), vomiting (21.2%) and hyperbilirubinemia (18.2%; none leading to treatment discontinuation). Serious adverse events occurred in 20.2% of patients. Laboratory grade 3-4 hyperbilirubinemia occurred in 9.2% and elevated total/pancreatic amylase in 33.7%/3.1%. At week 24, proportions with virologic suppression (HIV-1 RNA <50 copies/mL; intention-to-treat analysis) across weight bands were 10/23 (43.5%), 2/12 (16.5%), 10/21 (47.6%), 19/35 (54.3%) and 5/8 (62.5%), respectively. Virologic suppression was similar in antiretroviral-naïve/experienced patients and lowest in the 5 to <10 kg = 200/80 mg group, likely because of higher baseline HIV-1 RNA and discontinuation (66.7%). Overall, virologic suppression at weeks 24 (46.5%) and 48 (43.0%) was comparable. At week 48, 83.3% and 74.1% of caregivers reported no trouble giving ATV powder and RTV, respectively. ATV powder palatability, efficacy and lack of unexpected safety findings support its use for HIV-1-infected children ≥3 months to <11 years.

  15. Safety and efficacy of paliperidone palmitate 1-month formulation in Chinese patients with schizophrenia: a 25-week, open-label, multicenter, Phase IV study

    Directory of Open Access Journals (Sweden)

    Zhao JP

    2017-08-01

    Full Text Available Jingping Zhao,1,* Lehua Li,1,* Jianguo Shi,2 Yi Li,3 Xiufeng Xu,4 Keqing Li,5 Lili Zhang,6 Shangli Cai,6 Yu Feng,6 Jianmin Zhuo,6 Weihong Liu,6 Huafei Lu6 1Department of Psychiatry, The Mental Health Institute, The Second Xiangya Hospital of Central South University, 2Department of Psychiatry, Mental Health Center of Xi’an City, 3Department of Psychiatry, Mental Health Center of Wuhan City, 4Department of Psychiatry, First Affiliated Hospital of Kunming Medical University, 5Department of Psychiatry, The Sixth People’s Hospital of Hebei Province, 6Department of Medical Affairs, Xi’an Janssen Pharmaceutical Ltd., Beijing, People’s Republic of China *These authors contributed equally to this work Rationale: Long-acting injectable (LAI paliperidone palmitate 1-month formulation (PP1M has demonstrated acceptable tolerability and favorable clinical outcomes in Western and Asian patients with schizophrenia. Hence, analysis of the outcomes of long-term PP1M treatment specifically in Chinese patients is of interest.Objective: The aim of this study is to evaluate the long-term safety and efficacy of PP1M treatment in Chinese patients with schizophrenia.Methods: In this 25-week, open-label, Phase IV study, patients (18–65 years diagnosed with schizophrenia and having a baseline Positive and Negative Syndrome Scale (PANSS total score of 60–120 (inclusive were enrolled. All patients received injections of PP1M 150 mg eq. (day 1 and 100 mg eq. (day 8, followed by a flexible once-monthly maintenance dosing (75, 100, or 150 mg eq..Results: Of the 353 patients, 234 (66.3% completed the study treatment (mean age, 31.1 years; 52.7% men. The PANSS total score (primary end point improved significantly over the 6-month treatment period (mean [standard deviation] change from baseline to end of treatment, -27.2 [18.30]; P<0.0001. The Clinical Global Impressions-Severity and Personal and Social Performance scores (secondary end points also improved

  16. Immunogenicity and safety of a CRM-conjugated meningococcal ACWY vaccine administered concomitantly with routine vaccines starting at 2 months of age.

    Science.gov (United States)

    Nolan, Terry M; Nissen, Michael D; Naz, Aftab; Shepard, Julie; Bedell, Lisa; Hohenboken, Matthew; Odrljin, Tatjana; Dull, Peter M

    2014-01-01

    Infants are at the highest risk for meningococcal disease and a broadly protective and safe vaccine is an unmet need in this youngest population. We evaluated the immunogenicity and safety of a 4-dose infant/toddler regimen of MenACWY-CRM given at 2, 4, 6, and 12 months of age concomitantly with pentavalent diphtheria-tetanus-acellular pertussis-Hemophilus influenzae type b-inactivated poliovirus-combination vaccine (DTaP-IPV/Hib), hepatitis B vaccine (HBV), 7- or 13-valent conjugate pneumococcal vaccine (PCV), and measles, mumps, and rubella vaccine (MMR). Four doses of MenACWY-CRM induced hSBA titers ≥8 in 89%, 95%, 97%, and 96% of participants against serogroups A, C, W-135, and Y, respectively. hSBA titers ≥8 were present in 76-98% of participants after the first 3 doses. A categorical linear analysis incorporating vaccine group and study center showed responses to routine vaccines administered with MenACWY-CRM were non-inferior to routine vaccines alone, except for seroresponse to the pertussis antigen fimbriae. The reactogenicity profile was not affected when MenACWY-CRM was administered concomitantly with routine vaccines. MenACWY-CRM administered with routine concomitant vaccinations in young infants was well tolerated and induced highly immunogenic responses against each of the serogroups without significant interference with the immune responses to routine infant vaccinations. Healthy 2 month old infants were randomized to receive MenACWY-CRM with routine vaccines (n = 258) or routine vaccines alone (n = 271). Immunogenicity was assessed by serum bactericidal assay using human complement (hSBA). Medically attended adverse events (AEs), serious AEs (SAEs) and AEs leading to study withdrawal were collected throughout the study period.

  17. Fukushima-Dai-Ichi accident. Information bulletin no. 8 from December 12, 2011; Accident de Fukushima-Dai-Ichi - Bulletin d'information no. 8 du 12 decembre 2011

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2011-12-12

    This news bulletin has been prepared by the French institute of radiation protection and nuclear safety (IRSN) for the information of French residents in Japan. It presents, first, the situation at the date of the bulletin of the food chain contamination in the provinces close to the Fukushima Dai-ichi damaged site, the particular case of rice contamination monitoring and the controls performed at retailer shops. Then, it gives some general recommendations to residents concerning good food consumption and hygiene practices and recommends to avoid any unnecessary travel to the most impacted areas close to the prohibited access area. (J.S.)

  18. Immunogenicity, reactogenicity and safety of 2 doses of an adjuvanted herpes zoster subunit vaccine administered 2, 6 or 12 months apart in older adults: Results of a phase III, randomized, open-label, multicenter study.

    Science.gov (United States)

    Lal, Himal; Poder, Airi; Campora, Laura; Geeraerts, Brecht; Oostvogels, Lidia; Vanden Abeele, Carline; Heineman, Thomas C

    2018-01-02

    In phase III trials, 2 doses of a herpes zoster (HZ) subunit vaccine (HZ/su; 50 µg varicella-zoster virus glycoprotein E [gE] and AS01 B Adjuvant System) administered 2-months apart in older adults (≥50 and ≥70 years) demonstrated >90% efficacy in preventing HZ and had a clinically acceptable safety profile. Here we report immunogenicity, reactogenicity and safety following administration of 2 HZ/su doses at intervals longer than 2 months. In this Phase III, open-label trial conducted in the US and Estonia, 354 adults ≥50 years were randomized 1:1:1 to receive 2 HZ/su doses 2, 6, or 12 months apart. gE-specific humoral immune responses were evaluated at pre-vaccination, 1 and 12 months post-dose 2. Co-primary objectives were to compare immune responses to HZ/su 1 month post-dose 2 when given 6-months or 12-months apart to those administered 2-months apart. For each participant, safety information was collected from dose 1 to 12 months post-dose 2. 346 participants completed the study and 343 were included in the according-to-protocol cohort for immunogenicity. One month post-dose 2, vaccine response rates were 96.5% (97.5% confidence interval [CI]: 90.4; 99.2) and 94.5% (97.5% CI: 87.6; 98.3) for the 0, 6- and 0, 12-month schedules, respectively, both schedules meeting the pre-defined criterion. Non-inferiority of anti-gE geometric mean concentrations was demonstrated for HZ/su administered on 0, 6-month compared to a 0, 2-month schedule; however, HZ/su administered on a 0, 12-month schedule did not meet the non-inferiority criterion. Injection site pain was the most commonly reported solicited adverse event (AE). 26 participants each reported at least 1 serious AE; none were assessed as related to vaccination. Immune responses to HZ/su administered at 0, 6-month were non-inferior to those elicited by a 0, 2-month schedule. HZ/su exhibited a clinically acceptable safety profile for all dosing intervals. Clinicaltrials.gov (NCT01751165

  19. Once-monthly injection of paliperidone palmitate in patients with recently diagnosed and chronic schizophrenia: a post-hoc comparison of efficacy and safety.

    Science.gov (United States)

    Si, Tianmei; Zhuo, Jianmin; Turkoz, Ibrahim; Mathews, Maju; Tan, Wilson; Feng, Yu

    2017-12-01

    The use of long-acting injectable antipsychotics in recently diagnosed schizophrenia remains less explored. We evaluated the efficacy and safety of paliperidone palmitate once-monthly (PP1M) treatment in adult patients with recently diagnosed vs. chronic schizophrenia. These post-hoc analyses included two multicenter studies. Study 1 (NCT01527305) enrolled recently diagnosed (≤5 years) and chronic (>5 years) patients; Study 2 (NCT01051531) enrolled recently diagnosed patients only. Recently diagnosed patients were further sub-grouped into ≤2 years or 2-5 years. The primary efficacy endpoint was the change from baseline in Positive and Negative Syndrome Scale (PANSS) total score. In Study 1, 41.5% patients had recent diagnosis (≤2 years: 56.8%; 2-5 years: 43.2%); 58.5% had chronic schizophrenia. In Study 2, 52.8% and 47.2% patients were grouped into ≤2 years and 2-5 years, respectively. PANSS total score showed significantly greater improvement in patients with recently diagnosed vs. chronic schizophrenia. Similar results were obtained for PANSS responder rate, improvements in PANSS, and CGI-S scores. PP1M was efficacious in both recently diagnosed and chronic schizophrenia, with the benefits being more pronounced in patients with recently diagnosed schizophrenia. This adds to growing evidence recommending long-acting antipsychotic interventions at early stages of schizophrenia.

  20. 75 FR 67807 - Pipeline Safety: Emergency Preparedness Communications

    Science.gov (United States)

    2010-11-03

    ... DEPARTMENT OF TRANSPORTATION Pipeline and Hazardous Materials Safety Administration [Docket No... is issuing an Advisory Bulletin to remind operators of gas and hazardous liquid pipeline facilities... Gas Pipeline Systems. Subject: Emergency Preparedness Communications. Advisory: To further enhance the...

  1. Phase II, randomized, open, controlled study of AS03-adjuvanted H5N1 pre-pandemic influenza vaccine in children aged 3 to 9 years: follow-up of safety and immunogenicity persistence at 24 months post-vaccination.

    Science.gov (United States)

    Díez-Domingo, Javier; Baldó, José-María; Planelles-Catarino, Maria Victoria; Garcés-Sánchez, María; Ubeda, Isabel; Jubert-Rosich, Angels; Marès, Josep; Garcia-Corbeira, Pilar; Moris, Philippe; Teko, Maurice; Vanden Abeele, Carline; Gillard, Paul

    2015-03-01

    An AS03-adjuvanted H5N1 influenza vaccine elicited broad and persistent immune responses with an acceptable safety profile up to 6 months following the first vaccination in children aged 3-9 years. In this follow-up of the Phase II study, we report immunogenicity persistence and safety at 24 months post-vaccination in children aged 3-9 years. The randomized, open-label study assessed two doses of H5N1 A/Vietnam/1194/2004 influenza vaccine (1·9 μg or 3·75 μg hemagglutinin antigen) formulated with AS03A or AS03B (11·89 mg or 5·93 mg tocopherol, respectively). Control groups received seasonal trivalent influenza vaccine. Safety was assessed prospectively and included potential immune-mediated diseases (pIMDs). Immunogenicity was assessed by hemagglutination-inhibition assay 12 and 24 months after vaccination; cross-reactivity and cell-mediated responses were also assessed. (NCT00502593). The safety population included 405 children. Over 24 months, five events fulfilled the criteria for pIMDs, of which four occurred in H5N1 vaccine recipients, including uveitis (n = 1) and autoimmune hepatitis (n = 1), which were considered to be vaccine-related. Overall, safety profiles of the vaccines were clinically acceptable. Humoral immune responses at 12 and 24 months were reduced versus those observed after the second dose of vaccine, although still within the range of those observed after the first dose. Persistence of cell-mediated immunity was strong, and CD4(+) T cells with a TH 1 profile were observed. Two doses of an AS03-adjuvanted H5N1 influenza vaccine in children showed low but persistent humoral immune responses and a strong persistence of cell-mediated immunity, with clinically acceptable safety profiles up to 24 months following first vaccination. © 2014 The Authors. Influenza and Other Respiratory Viruses Published by John Wiley & Sons Ltd.

  2. What you think about the Bulletin

    CERN Multimedia

    Alizée Dauvergne

    2010-01-01

    The internal communication service has carried out a survey regarding the quality of the Bulletin. Between the middle of May and the middle of June, 35 members of the CERN personnel were consulted individually about what they liked and disliked about the Bulletin and any changes they wanted to see.   A wide readership The first point to emerge from the survey is that the Bulletin is read by a large proportion of the CERN population, even if opinions on its form and contents vary: 33 of the 35 people questioned said that they read it, representing 94.3%. Some even consider it as a point of reference: "If a subject isn’t featured in the Bulletin, I don't even know it exists!", said one young woman. Different reading habits Of course, almost all the people questioned don't read the Bulletin from cover to cover but select the information which concerns them personally or is on a subject of interest to them. The choice of articles read varies according to profession, job a...

  3. Compilation of fastener testing data received in response to NRC Compliance Bulletin 87-02

    International Nuclear Information System (INIS)

    Cwalina, G.C.; Conway, J.T.; Parker, L.B.

    1989-06-01

    On November 6, 1987, the Nuclear Regulatory Commission (NRC) issued Bulletin 87-02, ''Fastener Testing to Determine Conformance With Applicable Material Specifications,'' to all holders of operating licenses or construction permits for nuclear power reactors (licensees). The bulletin was issued so that the NRC staff could gather data to determine whether counterfeit fasteners are a problem in the nuclear power industry. The bulletin requested nuclear power plant owners to determine whether fasteners obtained from suppliers and/or manufacturers for use in their facilities meet the mechanical and chemical specifications stipulated in the procurement documents. The licensees were requested to sample a minimum of 10 safety-related and 10 non-safety-related fasteners (studs, bolts, and/or cap screws) and a sample of typical nuts that would be used with each fastener and to report the testing results to the NRC. The results of this study did not indicate a safety concern relating to the use of mismarked or counterfeit fasteners in the nuclear industry, but they did indicate a nonconformance rate of 8 to 12 percent for fasteners. The NRC staff is considering taking action to improve the effectiveness of receipt inspection and testing programs for all materials at nuclear power plants

  4. Safety and Immunogenicity of Coadministering a Combined Meningococcal Serogroup C and Haemophilus influenzae Type b Conjugate Vaccine with 7-Valent Pneumococcal Conjugate Vaccine and Measles, Mumps, and Rubella Vaccine at 12 Months of Age ▿

    OpenAIRE

    Miller, Elizabeth; Andrews, Nick; Waight, Pauline; Findlow, Helen; Ashton, Lindsey; England, Anna; Stanford, Elaine; Matheson, Mary; Southern, Joanna; Sheasby, Elizabeth; Goldblatt, David; Borrow, Ray

    2010-01-01

    The coadministration of the combined meningococcal serogroup C conjugate (MCC)/Haemophilus influenzae type b (Hib) vaccine with pneumococcal conjugate vaccine (PCV7) and measles, mumps, and rubella (MMR) vaccine at 12 months of age was investigated to assess the safety and immunogenicity of this regimen compared with separate administration of the conjugate vaccines. Children were randomized to receive MCC/Hib vaccine alone followed 1 month later by PCV7 with MMR vaccine or to receive all thr...

  5. A Case Study Exploring the Use of GarageBand[TM] and an Electronic Bulletin Board in Preservice Music Education

    Science.gov (United States)

    Vratulis, Vetta; Morton, Charlene

    2011-01-01

    This qualitative research study is an exploration of the merit and shortcomings of using a combination of the music software GarageBand[TM] and an electronic bulletin board to facilitate musical and peer learning in a 3-month elementary music methods curriculum and instruction course. A pedagogical objective of this assignment was to increase the…

  6. Safety of Sodium-Glucose Cotransporter 2 Inhibitors (SGLT2-I During the Month of Ramadan in Muslim Patients with Type 2 Diabetes

    Directory of Open Access Journals (Sweden)

    Alaaeldin Bashier

    2018-03-01

    Full Text Available Objectives: Sodium-glucose cotransporter 2 inhibitors (SGLT2-I are a new class of antidiabetic drugs that might increase the risk of dehydration and hypoglycemia, particularly during the month of Ramadan in which Muslims abstain from eating and drinking for 14–16 hours daily. We aimed to provide real-life evidence about the safety of SGLT2-I during Ramadan. Methods: All patients over the age of 18 years on SGLT2-I before Ramadan 2016 who would be fasting during Ramadan were included. Demographic data, detailed medical history including comorbidities and medication profile, and laboratory results were collected before and after Ramadan. We also conducted a phone interview to evaluate the frequency and severity of hypoglycemia and dehydration. Results: Of the total of 417 patients, 113 (27.0% experienced hypoglycemic events, and 93 of these (82.3% checked their blood glucose using a glucometer. Confirmed hypoglycemia (< 70 mg/dL was observed in 78 (83.8%. The hypoglycemic events were significantly more frequent in the SGLT2-I plus insulin-treated group than in those treated with SGLT2-I plus oral hypoglycemic agents group (p < 0.001. Confirmed hypoglycemic events were more frequent in those using SGLT2-I plus intensive insulin compared to those using SGLT2-I plus basal insulin (p = 0.020. Symptoms of dehydration were seen in 9.3% (n = 39 of the total population. We observed statistically significant reductions in glycated hemoglobin and weight by the end of Ramadan (p < 0.001. There were no significant changes in lipid profile and creatinine levels by the end of the study. Conclusions: The use of insulin in combination with SGLT2-I increases the risk of hypoglycemia during Ramadan. Hypoglycemic events were mild and did not require hospital admission. However, careful monitoring during prolonged fasting is warranted. No significant harmful effects on renal function result from treatment with SGLT2-I during Ramadan.

  7. Annual bulletin of coal statistics for Europe. [1970 to 1975; by country; Europe plus USA and Canada; no text

    Energy Technology Data Exchange (ETDEWEB)

    1975-01-01

    The purpose of this report is to provide basic data on developments and trends in the field of solid fuels in European countries, Canada and the United States of America. The data refer to production, stocks, inland availabilities, deliveries, trade, employment, and labour productivity. The Annual Bulletin is supplemented by a Quarterly Bulletin of Coal Statistics for Europe which contains monthly data on production, trade, stocks and inland availabilities. Both publications are purely statistical in character. For an analysis of the coal situation and its prospects, reference may be made to the periodic reviews prepared by the secretariat of the United Nations Economic Commission for Europe.

  8. SCIENTIFIC AND PRACTICAL ASPECTS OF THE BULLETINS DEVELOPMENT FOR CIVIL AIRCRAFT

    Directory of Open Access Journals (Sweden)

    Andrey N. Petrov

    2017-01-01

    Full Text Available The paper outlines science and methodological aspects of issuing bulletins for the civil aircraft and practical prob- lems accumulated in the national aviation industry within the mentioned area. Bulletins are used to inform operators about the purpose, data content and technologies outlining the design changes accomplishment if the aircraft considered at the moment of the design changes is already at the operational stage. Hence maintaining aircraft airworthiness is impossible without making certain modifications and repairs in the design, the bulletins issuing and implementation procedures have notable impact on safety and effectiveness of air transportation.Deficiencies considered are the results of practices used since 1980 and supported by the later interstate standard GOST 31270-2004 in the field of the bulletins development and implementation, which are not in line with contemporary conditions of international civil aviation activities. Negative consequences of transferring the Soviet way of working with aircraft bulletins intothe changed conditions of the state regulation of civil aviation activities in Russia are shown as well as those for substantial com-plication of the rules and procedures in comparison to the standards of Unified System of Design Documentation.Main theses of the ICAO standards and international practice are briefly analyzed, however they are not complete- ly presented in the national aviation regulations. The recommendations proposed are aimed to eliminate mentioned defi- ciencies through the standards amendment process and improvement of Russia's civil aviation regulatory base. Developed recommendations are mainly focused on the formulation of the new concept and certain content of the revised standard requirements to replace GOST 31270-2004.

  9. Nuclear Law Bulletin No. 95. Volume 2015/1

    International Nuclear Information System (INIS)

    2015-01-01

    The Nuclear Law Bulletin is a unique international publication for both professionals and academics in the field of nuclear law. It provides readers with authoritative and comprehensive information on nuclear law developments. Published free online twice a year in both English and French, it features topical articles written by renowned legal experts, covers legislative developments worldwide and reports on relevant case law, bilateral and international agreements as well as regulatory activities of international organisations. Feature articles in this issue include 'Entry into force of the Convention on Supplementary Compensation for Nuclear Damage: Opening the umbrella'; 'Towards a new international framework for nuclear safety: Developments from Fukushima to Vienna'; 'Nuclear arbitration: Interpreting non-proliferation agreements'. Other chapters deal with case laws, legislative and regulatory activities, intergovernmental organisation activities, and documents and legal texts

  10. NASA aviation safety reporting system

    Science.gov (United States)

    1981-01-01

    Aviation safety reports that relate to loss of control in flight, problems that occur as a result of similar sounding alphanumerics, and pilot incapacitation are presented. Problems related to the go around maneuver in air carrier operations, and bulletins (and FAA responses to them) that pertain to air traffic control systems and procedures are included.

  11. SAFETY

    CERN Multimedia

    M. Plagge, C. Schaefer and N. Dupont

    2013-01-01

    Fire Safety – Essential for a particle detector The CMS detector is a marvel of high technology, one of the most precise particle measurement devices we have built until now. Of course it has to be protected from external and internal incidents like the ones that can occur from fires. Due to the fire load, the permanent availability of oxygen and the presence of various ignition sources mostly based on electricity this has to be addressed. Starting from the beam pipe towards the magnet coil, the detector is protected by flooding it with pure gaseous nitrogen during operation. The outer shell of CMS, namely the yoke and the muon chambers are then covered by an emergency inertion system also based on nitrogen. To ensure maximum fire safety, all materials used comply with the CERN regulations IS 23 and IS 41 with only a few exceptions. Every piece of the 30-tonne polyethylene shielding is high-density material, borated, boxed within steel and coated with intumescent (a paint that creates a thick co...

  12. SAFETY

    CERN Multimedia

    C. Schaefer and N. Dupont

    2013-01-01

      “Safety is the highest priority”: this statement from CERN is endorsed by the CMS management. An interpretation of this statement may bring you to the conclusion that you should stop working in order to avoid risks. If the safety is the priority, work is not! This would be a misunderstanding and misinterpretation. One should understand that “working safely” or “operating safely” is the priority at CERN. CERN personnel are exposed to different hazards on many levels on a daily basis. However, risk analyses and assessments are done in order to limit the number and the gravity of accidents. For example, this process takes place each time you cross the road. The hazard is the moving vehicle, the stake is you and the risk might be the risk of collision between both. The same principle has to be applied during our daily work. In particular, keeping in mind the general principles of prevention defined in the late 1980s. These principles wer...

  13. 77 FR 40358 - Federal Management Regulation; FMR Bulletin PBS-2012-03; Redesignations of Federal Buildings...

    Science.gov (United States)

    2012-07-09

    ... Management Regulation; FMR Bulletin PBS-2012-03; Redesignations of Federal Buildings: Correction AGENCY: Public Buildings Service (PBS), General Services Administration (GSA). ACTION: Notice of a bulletin..., 2012, a bulletin announcing the designation and redesignation of three Federal buildings. Inadvertently...

  14. IE Bulletin No. 79-01: Environmental qualification of Class IE equipment

    International Nuclear Information System (INIS)

    Anon.

    1993-01-01

    The intent of IE Circular 78-08 was to highlight to all licensees important lessons learned from environmental qualification deficiencies reported by individual licensees. In this regard, licensees were requested to examine installed safety-related electrical equipment and determine that proper documentation existed which provided assurance that this equipment would function under postulated accident conditions. The intent of this Bulletin is to raise the threshold of IE Circular 78-08 to the level of a Bulletin; i.e., action requiring a licensee response. Inspections conducted to date by the NRC of licensees' activities in response to IE Circular 78-08 have identified one component which licensees have found to be unqualified for service within the LOCA environment. Specifically, unqualified stem mounted limit switches (SMLS), other than those identified in previously issued IE Bulletin 78-04, were found to be installed on safety-related valves inside containment at both Duane Arnold and Quad Cities 1 and 2 Nuclear Generating Stations. According to the manufacturer, these switches are designed only for general purpose applications and are not considered suitable devices for service in the LOCA environment. Consequently, switches are being replaced at the above power plants with qualified components

  15. Efficacy and Safety of Multiple Doses of Exenatide Once-Monthly Suspension in Patients With Type 2 Diabetes: A Phase II Randomized Clinical Trial.

    Science.gov (United States)

    Wysham, Carol H; MacConell, Leigh; Hardy, Elise

    2016-10-01

    This study investigated the efficacy and safety of multiple exenatide once-monthly suspension (QMS) doses of exenatide-containing microspheres in Miglyol referenced against the clinical dose of exenatide once-weekly (QW) microspheres in aqueous solution. In this phase II, randomized, controlled, single-blind study, 121 adults (∼30/arm) with type 2 diabetes and HbA1c 7.1-11.0% (54-97 mmol/mol) were randomized 1:1:1:1 to subcutaneous exenatide QW 2 mg (self-administered) or exenatide QMS 5, 8, or 11 mg (caregiver-administered) for 20 weeks. The primary end point was change in HbA1c. At baseline, mean age was 50 years, HbA1c was 8.5% (69 mmol/mol), fasting plasma glucose (FPG) was 184 mg/dL, and body weight was 98 kg. At week 20, mean ± SD HbA1c reductions were -1.54% ± 1.26% with exenatide QW and -1.29% ± 1.07%, -1.31% ± 1.66%, and -1.45% ± 0.93% with exenatide QMS 5, 8, and 11 mg, respectively (evaluable population: n = 110). There were no significant differences in HbA1c reductions among the exenatide QMS doses. FPG reductions were -34 ± 48 mg/dL with exenatide QW and -25 ± 43, -30 ± 52, and -49 ± 49 mg/dL with exenatide QMS 5, 8, and 11 mg, respectively. Weight decreased with all treatments. For exenatide QMS, nausea (16.7-23.3%) and headache (16.7-26.7%) were the most common adverse events. No major or minor hypoglycemia occurred. All doses of exenatide QMS resulted in efficacy and tolerability profiles consistent with exenatide QW. These results combined with pharmacokinetic and pharmacodynamic modeling could inform dose selection for further development. © 2016 by the American Diabetes Association.

  16. Fukushima-Daiichi accident. News bulletin no. 4 from April 20

    International Nuclear Information System (INIS)

    2011-01-01

    This news bulletin has been prepared by the French institute of radiation protection and nuclear safety (IRSN) for the information of French residents in Japan. It presents, first, the situation at the date of the bulletin of the reactors at the power plant site, the accident management actions in progress, the radioactive contamination around the site, the evolution of ambient dose rates measured at Tokyo since March 18, the radioactive fallouts and the contamination of food products (vegetables, mushrooms, milk and meat) and drinking water, the contamination of seawater and of fishes and other marine species. Then, it gives some general recommendations to residents concerning food consumption and dwelling hygiene, in particular for the most impacted areas. Finally, some scientific information about radioactivity, biological radiation effects (external and internal exposure) and dosimetry are given. (J.S.)

  17. Fukushima-Daiichi accident. News bulletin no. 2 from April 8

    International Nuclear Information System (INIS)

    2011-01-01

    This news bulletin has been prepared by the French institute of radiation protection and nuclear safety (IRSN) for the information of French residents in Japan. It presents, first, the situation at the date of the bulletin of the reactors at the power plant site, the accident management actions in progress, the radioactive contamination around the site, the evolution of radioactivity in the air of Tokyo since March 15, the meteorological forecasts, and the impact of the April 7 earthquake. Then, it gives some general recommendations to residents concerning food consumption and dwelling hygiene. Finally, some scientific information about radionuclides migration, radioactive pollution and their environmental impact are given. The geographic distribution of radioactive fallouts around the Fukushima-Daiichi site is shown. (J.S.)

  18. Fukushima-Daiichi accident. News bulletin no. 3 from April 13

    International Nuclear Information System (INIS)

    2011-01-01

    This news bulletin has been prepared by the French institute of radiation protection and nuclear safety (IRSN) for the information of French residents in Japan. It presents, first, the situation at the date of the bulletin of the reactors at the power plant site, the accident management actions in progress, the radioactive contamination around the site, the evolution of radioactivity in the air of Tokyo since March 15, the meteorological forecasts, and the impact of the April 7 earthquake. Then, it gives some general recommendations to residents concerning food consumption and dwelling hygiene. Finally, some scientific information about radionuclides migration, radioactive pollution and their environmental impact are given. The kinetics of plants contamination is explained. (J.S.)

  19. Fukushima-Daiichi accident. News bulletin no. 5 from April 29

    International Nuclear Information System (INIS)

    2011-01-01

    This news bulletin has been prepared by the French institute of radiation protection and nuclear safety (IRSN) for the information of French residents in Japan. It presents, first, the situation at the date of the bulletin of the reactors at the power plant site, the accident management actions in progress, the radioactive contamination around the site, the evolution of ambient dose rates measured at Tokyo since March 18, the radioactive fallouts and the contamination of food products (vegetables, mushrooms, milk and meat) and drinking water, the contamination of seawater and of fishes and other marine species. Then, it gives some general recommendations to residents concerning food consumption and dwelling hygiene, in particular for the most impacted areas. Finally, some scientific information about radioactivity, biological radiation effects (external and internal exposure) and dosimetry are given. (J.S.)

  20. Bulletin Boards: The Great Corkboard Wasteland.

    Science.gov (United States)

    Reith, James W.

    1970-01-01

    A successful classroom bulletin board display should not only be decorative, but also must have clear-cut purposes and functions: informational (i.e., post current school news), instructional (i.e., expand on classroom units), and motivational (i.e., tap subliminal awareness). Some suggested techniques include (1) using space other than the…

  1. Credit Cards. Bulletin No. 721. (Revised.)

    Science.gov (United States)

    Fox, Linda Kirk

    This cooperative extension bulletin provides basic information about credit cards and their use. It covers the following topics: types of credit cards (revolving credit, travel and entertainment, and debit); factors to consider when evaluating a credit card (interest rates, grace period, and annual membership fee); other credit card costs (late…

  2. Family Violence & Sexual Assault Bulletin, 1996.

    Science.gov (United States)

    Geffner, Robert, Ed.

    These two Bulletins contain selected articles that highlight research and treatment issues in child abuse and child sexual abuse. The first issue includes the following featured articles: (1) "The Relationships between Animal Abuse and Other Forms of Family Violence" (Phil Arkow), which addresses animal cruelty as a harbinger of…

  3. Electronic bulletin board. OCRWM INFOLINK. Revision

    International Nuclear Information System (INIS)

    1986-04-01

    This user's manual provides instructions for access to OCRWM INFOLINK (an electronic bulletin board). INFOLINK provides current program information and access to texts of: press releases; fact sheets/backgrounders; comgressional questions and answers; congressional testimony; speeches; schedules (milestones, meetings, and activities); and miscellaneous announcements

  4. Updating default depths in the ISC bulletin

    Science.gov (United States)

    Bolton, Maiclaire K.; Storchak, Dmitry A.; Harris, James

    2006-09-01

    The International Seismological Centre (ISC) publishes the definitive global bulletin of earthquake locations. In the ISC bulletin, we aim to obtain a free depth, but often this is not possible. Subsequently, the first option is to obtain a depth derived from depth phases. If depth phases are not available, we then use the reported depth from a reputable local agency. Finally, as a last resort, we set a default depth. In the past, common depths of 10, 33, or multiples of 50 km have been assigned. Assigning a more meaningful default depth, specific to a seismic region will increase the consistency of earthquake locations within the ISC bulletin and allow the ISC to publish better positions and magnitude estimates. It will also improve the association of reported secondary arrivals to corresponding seismic events. We aim to produce a global set of default depths, based on a typical depth for each area, from well-constrained events in the ISC bulletin or where depth could be constrained using a consistent set of depth phase arrivals provided by a number of different reporters. In certain areas, we must resort to using other assumptions. For these cases, we use a global crustal model (Crust2.0) to set default depths to half the thickness of the crust.

  5. Nuclear medicine. Czech special bulletin. No. 2

    International Nuclear Information System (INIS)

    1991-09-01

    The bulletin contains the article on the first experience with the CERTEC preparation in examination of brain perfusion and the article on the potential for the development and manufacture of radiopharmaceutical kits. Both articles are inputted into INIS. (J.B.)

  6. A double Weekly Bulletin over Easter

    CERN Multimedia

    2004-01-01

    During the Easter period, the weeks of 12 and 19 April, there will be only one issue of the Weekly Bulletin (no. 16-17/2004). Announcements for publication in the next issue (no. 18/2004) should be sent on Tuesday 20 April midday at the latest. Publication Section Tel. 79971

  7. CERN Bulletin publication schedule for 2014

    CERN Multimedia

    DG Unit

    2013-01-01

    The table below lists the 2014 publication dates for the CERN Bulletin and the corresponding deadlines for the submission of announcements. Please note that all announcements must be submitted by 12.00 noon on Tuesdays at the latest.   Bulletin No. (corresponding to the week number) Submission of announcements (before 12.00 midday) Bulletin Web version Bulletin Printed version 4-5   Tuesday 14 January Friday 17 January Wednesday 22 January 6-7   Tuesday 28 January Friday 31 January Wednesday 5 February 8-9 Tuesday 11 February Friday 14 February Wednesday 19 February 10-11 Tuesday 25 February Friday 28 February Wednesday 5 March 12-13 Tuesday 11 March Friday 14 March Wednesday 19 March 14-15 Tuesday 25 March Friday 28 March Wednesday 2 April 16-17 Tuesday 8 April Friday 11 April Wednesday 16 April 18-19 Tuesday 22 April Friday 25 April Thursday 30 April 20-21 Tuesday 6 May Friday 9 May Wednesday 14 May 22-23 Tuesday ...

  8. Safety

    International Nuclear Information System (INIS)

    Jones, P.M.S.

    1987-01-01

    Aspects of fission reactors are considered - control, heat removal and containment. Brief descriptions of the reactor accidents at the SL-1 reactor (1961), Windscale (1957), Browns Ferry (1975), Three Mile Island (1979) and Chernobyl (1986) are given. The idea of inherently safe reactor designs is discussed. Safety assessment is considered under the headings of preliminary hazard analysis, failure mode analysis, event trees, fault trees, common mode failure and probabalistic risk assessments. These latter can result in a series of risk distributions linked to specific groups of fault sequences and specific consequences. A frequency-consequence diagram is shown. Fatal accident incidence rates in different countries including the United Kingdom for various industries are quoted. The incidence of fatal cancers from occupational exposure to chemicals is tabulated. Human factors and the acceptability of risk are considered. (U.K.)

  9. NHTSA's Office of Defects Investigation (ODI) - Technical Service Bulletins System (TSBS) - Downloadable file

    Data.gov (United States)

    Department of Transportation — The Technical Service Bulletins data contains summaries of the Manufacturers' Technical Service Bulletins by single year, make and model. An optional item of Vehicle...

  10. Safety and efficacy of ranibizumab in diabetic macular edema (RESOLVE Study): a 12-month, randomized, controlled, double-masked, multicenter phase II study

    DEFF Research Database (Denmark)

    Massin, Pascale; Bandello, Francesco; Garweg, Justus G

    2010-01-01

    The expression of vascular endothelial growth factor (VEGF) is elevated in diabetic macular edema (DME). Ranibizumab binds to and inhibits multiple VEGF variants. We investigated the safety and efficacy of ranibizumab in DME involving the foveal center.......The expression of vascular endothelial growth factor (VEGF) is elevated in diabetic macular edema (DME). Ranibizumab binds to and inhibits multiple VEGF variants. We investigated the safety and efficacy of ranibizumab in DME involving the foveal center....

  11. Dams. Bulletin of the Technical Service of Electric Power and Big Dams; Barrages. Bulletin du Service Technique de l`Energie Electrique et des Grands Barrages

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-12-31

    Three papers were selected in this issue of the bulletin of the Technical Service of Electric Power and Big Dams. The first one concerns the experience feedback gained from the accident of the Drac river near Grenoble (France) due to a spillover at the Notre-Dame-de-Commiers` dam and which led to the death of 6 children and their teacher. The second one is a report of the conclusions of decennial and annual safety inspections of French dams, while the third one is a report of the Control Services activities for the third quarter of the year 1996 concerning the French dams in operation. (J.S.)

  12. Dams. Bulletin of the technical service of electric power and big dams; Barrages. Bulletin du service technique de l`energie electrique et des grands barrages (STEEGB)

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1997-12-31

    Four papers were selected in this issue of `Barrages` bulletin. The first one concerns the surveillance of medium size dams, the second one deals with the life of French dams in operation (safety decennial and annual inspections). The third paper describes the behaviour of free flow spillways installed on loam dams while the last paper reports on the activities of the control service of the STEEGB for the second quarter of 1997 (decennial and annual inspections, important facts, administrative instructions, draining, floods, granting etc..). (J.S.)

  13. BJPsych Bulletin author mentoring scheme – helping trainees become published authors

    Science.gov (United States)

    Pimm, Jonathan; Galbraith, Niall

    2016-01-01

    The publishing world is changing rapidly. Innovations include the move to open access, the rise of social media and the transition to digitalisation. In the light of these developments and with ever-increasing pressures on early career psychiatrists and trainees to publish papers in journals with a recognised pedigree, the BJPsych Bulletin is piloting an author mentoring scheme. Mentors will help clinicians and aspiring academics develop articles from a pedestrian manuscript to one that will hopefully provoke important debate and aid changes in current practices. The scheme will run on a trial basis for approximately 12 months and will then be reviewed. Mentoring has been found to have an important effect of research output including publication and grant success; the hope is that this new initiative at the BJPsych Bulletin will result in such dividends to all involved. PMID:26958356

  14. A randomized study to evaluate the immunogenicity and safety of a heptavalent diphtheria, tetanus, pertussis, hepatitis B, poliomyelitis, haemophilus influenzae b, and meningococcal serogroup C combination vaccine administered to infants at 2, 4 and 12 months of age.

    Science.gov (United States)

    Thollot, Franck; Scheifele, David; Pankow-Culot, Heidemarie; Cheuvart, Brigitte; Leyssen, Maarten; Ulianov, Liliana; Miller, Jacqueline M

    2014-12-01

    The immunogenicity and safety of the investigational diphtheria, tetanus, acellular pertussis, hepatitis B, poliomyelitis, Haemophilus influenzae type b (Hib) and meningococcal serogroup C (MenC) heptavalent combination vaccine were compared with those of licensed control vaccines. In this open, phase II, randomized study (NCT01090453), 480 infants from Germany, France and Canada received the heptavalent vaccine (Hepta group) or hexavalent and monovalent MenC control vaccines (HexaMenC group) co-administered with a 13-valent pneumococcal conjugate vaccine at 2, 4 and 12 months of age. Immunogenicity was measured 1 month after the second primary dose, and before and 1 month after the booster dose. Safety and reactogenicity were also evaluated. Non-inferiority of immune responses to MenC and Hib induced by 2-dose primary vaccination with the heptavalent vaccine versus control vaccines was demonstrated. In exploratory analyses, postprimary and postbooster functional antibody geometric mean titers against MenC tended to be lower (1119.5 vs. 3200.5; 2653.8 vs. 6028.4) and antibody geometric mean concentrations against Hib higher (1.594 vs. 0.671 μg/mL; 17.678 vs. 13.737 μg/mL) in the Hepta versus the HexaMenC group. The heptavalent and control vaccines were immunogenic to all other antigens, although immune responses to poliovirus were lower than expected in both groups. No differences in safety and reactogenicity profiles were detected between groups. The heptavalent vaccine induced non-inferior MenC and Hib responses compared with control vaccines. Both vaccination regimens, when administered at 2, 4 and 12 months of age, had comparable safety profiles and were immunogenic to all antigens, with lower-than-expected responses to poliomyelitis.

  15. Efficacy and safety of a 3-month loteprednol etabonate 0.5% gel taper for routine prophylaxis after photorefractive keratectomy compared to a 3-month prednisolone acetate 1% and fluorometholone 0.1% taper

    Directory of Open Access Journals (Sweden)

    Mifflin MD

    2017-06-01

    Full Text Available Mark D Mifflin,1 Brent S Betts,1 P Adam Frederick,2 Jason M Feuerman,3 Carlton R Fenzl,4 Majid Moshirfar,1,5 Brian Zaugg1 1Department of Ophthalmology and Visual Sciences, John A Moran Eye Center, University of Utah, Salt Lake City, UT, 2The Eye Center, Huntsville, AL, 3Eye Institute of Austin, Austin, TX, 4Eye Surgeons Associates, Bettendorf, IA, 5Hoopes Vision, Draper, UT, USA Purpose: To compare the outcome of photorefractive keratectomy (PRK and complications in patients treated with either loteprednol etabonate 0.5% gel or prednisolone acetate 1% suspension and fluorometholone (fml 0.1% suspension.Setting: John A Moran Eye Center, University of Utah, Salt Lake City, UT, USA.Design: Prospective, randomized, partially masked trial.Methods: PRK was performed on 261 eyes of 132 participants. Patients were randomized to a postoperative corticosteroid regimen of either loteprednol etabonate 0.5% gel (loteprednol or prednisolone 1% acetate suspension followed by fluorometholone 0.1% suspension (prednisolone/fml. Primary outcome measures included incidence and grade of postoperative corneal haze and incidence of increased intraocular pressure of 10 mmHg above baseline, or any intraocular pressure over 21 mmHg. Secondary outcome measures included uncorrected distance visual acuity, best corrected distance visual acuity, and manifest refraction spherical equivalent.Results: The incidence of haze in the first 3 months was 2.6% (3/114 eyes in the loteprednol group and 4.8% (7/147 eyes in the prednisolone/fml group and was not statistically significant between groups (P=0.37. The incidence of elevated intraocular pressure was 1.8% (2/114 eyes in the loteprednol group and 4.1% (6/147 eyes in the prednisolone/fml group, and was not statistically significant between the groups (P=0.12. The mean 3-month postoperative logMAR uncorrected visual acuity was −0.078±0.10 and −0.075±0.09 in the loteprednol and prednisolone/fml groups, respectively (P=0

  16. Bosutinib efficacy and safety in chronic phase chronic myeloid leukemia after imatinib resistance or intolerance : Minimum 24-month follow-up

    NARCIS (Netherlands)

    Gambacorti-Passerini, Carlo; Brümmendorf, Tim H; Kim, Dong-Wook; Turkina, Anna G; Masszi, Tamas; Assouline, Sarit; Durrant, Simon; Kantarjian, Hagop M; Khoury, H Jean; Zaritskey, Andrey; Shen, Zhi-Xiang; Jin, Jie; Vellenga, Edo; Pasquini, Ricardo; Mathews, Vikram; Cervantes, Francisco; Besson, Nadine; Turnbull, Kathleen; Leip, Eric; Kelly, Virginia; Cortes, Jorge E

    Bosutinib is an orally active, dual Src/Abl tyrosine kinase inhibitor for treatment of chronic myeloid leukemia (CML) following resistance/intolerance to prior therapy. Here, we report the data from the 2-year follow-up of a phase 1/2 open-label study evaluating the efficacy and safety of bosutinib

  17. Safety and immunogenicity of coadministering a combined meningococcal serogroup C and Haemophilus influenzae type b conjugate vaccine with 7-valent pneumococcal conjugate vaccine and measles, mumps, and rubella vaccine at 12 months of age.

    Science.gov (United States)

    Miller, Elizabeth; Andrews, Nick; Waight, Pauline; Findlow, Helen; Ashton, Lindsey; England, Anna; Stanford, Elaine; Matheson, Mary; Southern, Joanna; Sheasby, Elizabeth; Goldblatt, David; Borrow, Ray

    2011-03-01

    The coadministration of the combined meningococcal serogroup C conjugate (MCC)/Haemophilus influenzae type b (Hib) vaccine with pneumococcal conjugate vaccine (PCV7) and measles, mumps, and rubella (MMR) vaccine at 12 months of age was investigated to assess the safety and immunogenicity of this regimen compared with separate administration of the conjugate vaccines. Children were randomized to receive MCC/Hib vaccine alone followed 1 month later by PCV7 with MMR vaccine or to receive all three vaccines concomitantly. Immunogenicity endpoints were MCC serum bactericidal antibody (SBA) titers of ≥8, Hib-polyribosylribitol phosphate (PRP) IgG antibody concentrations of ≥0.15 μg/ml, PCV serotype-specific IgG concentrations of ≥0.35 μg/ml, measles and mumps IgG concentrations of >120 arbitrary units (AU)/ml, and rubella IgG concentrations of ≥11 AU/ml. For safety assessment, the proportions of children with erythema, swelling, or tenderness at site of injection or fever or other systemic symptoms for 7 days after immunization were compared between regimens. No adverse consequences for either safety or immunogenicity were demonstrated when MCC/Hib vaccine was given concomitantly with PCV and MMR vaccine at 12 months of age or separately at 12 and 13 months of age. Any small differences in immunogenicity were largely in the direction of a higher response when all three vaccines were given concomitantly. For systemic symptoms, there was no evidence of an additive effect; rather, any differences between schedules showed benefit from the concomitant administration of all three vaccines, such as lower overall proportions with postvaccination fevers. The United Kingdom infant immunization schedule now recommends that these three vaccines may be offered at one visit at between 12 and 13 months of age.

  18. A uniform seismological bulletin for the European - Mediterranean region

    International Nuclear Information System (INIS)

    Bossu, R.; Piedfroid, O.; Riviere, F.

    2002-01-01

    The goal of this EU funded project is to develop means and tools to produce a homogeneous European-Mediterranean seismic bulletin that could serve as a reference. The 3 main objectives are 1) the definition of a unified magnitude scale for M > 3, 2) an improved location of events especially in border regions, 3) Improving rapid and regular data exchange within the European-Mediterranean region. The first step is to define an homogeneous and accurate magnitude estimation for the whole region of interest. Experience shows that the differences in the magnitudes reported by several institutes for a given event may vary up to 1.5 units. Three different magnitude computations are applied on a reference data set of well known events: a Lg waves coda magnitude, a Richter local magnitude and a moment magnitude scale. The comparison of the results is currently carried out. The algorithm associated to the selected magnitude will be implemented locally on a set of stations. New velocity models for border regions are developed from the analysis of the residuals of events recorded by permanent and temporary networks. The robustness and reliability of the 3D models versus 1D model have been evaluated. EMSC gathers via e-mail manually picked seismic phase arrival times with or without associated locations from about 50 seismological institutes of the European- Mediterranean region in a database. These bulletins are automatically merged by unique software. The number of processed events is about 2000 / month and should grow significantly with larger input from Middle East and Northern Africa. Events are then submitted to an automatic analysis of the location reliability, and, for dubious events, to a manual reprocessing. In order to improve data exchange, the installation of autoDRM systems is promoted. (authors)

  19. Rebuild of the Bulletin of the International Seismological Centre (ISC), part 1: 1964-1979

    Science.gov (United States)

    Storchak, Dmitry A.; Harris, James; Brown, Lonn; Lieser, Kathrin; Shumba, Blessing; Verney, Rebecca; Di Giacomo, Domenico; Korger, Edith I. M.

    2017-12-01

    The data from the Bulletin of the International Seismological Centre (ISC) have always been and still remain in demand for a wide range of studies in Geosciences. The unique features of the Bulletin include long-term coverage (1904-present), the most comprehensive set of included seismic data from the majority of permanent seismic networks at any given time in the history of instrumental recording (currently 150) and homogeneity of the data and their representation. In order to preserve this homogeneity, the ISC has followed its own standard seismic event processing procedures that have not substantially changed until the early 2000s. Several considerable and necessary advancements in the ISC data collection and seismic event location procedures have created a need to rebuild the data for preceding years in line with the new procedures. Thus was set up a project to rebuild the ISC Bulletin for the period from the beginning of the ISC data till the end of data year 2010. The project is known as the Rebuild of the ISC Bulletin. From data month of January 2011, the ISC data have already been processed with the fully tested and established new procedures and do not require an alteration. It was inconceivable even to think about such a project for many tens of years, but great advances in computer power and increased support by the ISC Member-Institutions and Sponsors have given us a chance to perform this project. Having obtained a lot of experience on the way, we believe that within a few years the entire period of the ISC data will be reprocessed and extended for the entire period of instrumental seismological recordings from 1904 till present. The purpose of this article is to describe the work on reprocessing the ISC Bulletin data under the Rebuild project. We also announce the release of the rebuilt ISC Bulletin for the period 1964-1979 with all seismic events reprocessed and relocated in line with the modern ISC procedures, 68,000 new events, 255 new stations

  20. Publication of the bulletin in 2009

    CERN Document Server

    DG Unit

    2009-01-01

    The table below lists the 2009 publication dates for the paper version of the Bulletin and the corresponding deadlines for the submission of announcements. Please note that all announcements must be submitted by 12.00 midday on Tuesdays at the latest. Bulletin No. Week number Submission of announcements (before 12.00 midday) Publication date 3-4 Tuesday 6 January Monday 12 January 5-6 Tuesday 20 January Monday 26 January 7-8 Tuesday 3 February Monday 9 February 9-10 Tuesday 17 February Monday 23 February 11-12 Tuesday 3 March Monday 9 March 13-14 Tuesday 17 March Monday 23 March 15-16-17 (Easter issue) Tuesday 31 March Monday 6 April 18-19 Tuesday 21 April Monday 27 April 20-21 Tuesday 5 May Monday 11 May 22-23 Tuesday 19 May Monday 25 May 24-25 ...

  1. The effect of 12-month dehydroepiandrosterone supplementation on the menstrual pattern, ovarian reserve markers, and safety profile in women with premature ovarian insufficiency.

    Science.gov (United States)

    Wong, Queenie Ho Yan; Yeung, Tracy Wing Yee; Yung, Sofie Shuk Fei; Ko, Jennifer Ka Yee; Li, Hang Wun Raymond; Ng, Ernest Hung Yu

    2018-03-09

    To evaluate the effect of 12-month DHEA supplementation on menstrual pattern and ovarian reserve markers in women with premature ovarian insufficiency (POI) METHODS: This is a prospective observational study. Women with POI were given DHEA supplements (25 mg three times daily) for 12 months. Sonographic assessment for ovarian volume and antral follicle count (AFC) and serum measurement for anti-Mullerian hormone (AMH), follicle stimulating hormone (FSH), estradiol, testosterone, liver function, and hemoglobin level were performed at baseline and monthly for 13 months after the supplementation. Menstrual pattern, ovarian reserve markers, and side-effects were recorded. Between August 2011 and July 2014, 38 women with POI were recruited and 31 completed the study. The median age of women was 36 years, and the median baseline FSH and AMH concentrations were 82.2 IU/L and 0.01 ng/ml, respectively. No women had resumption of regular menstruation after DHEA supplementation. AMH, FSH, and AFC did not change significantly. No serious side effects were reported. Our results do not support any significant improvement in ovarian function by 12-month DHEA supplementation in women with POI.

  2. A double Weekly Bulletin over Easter

    CERN Multimedia

    2004-01-01

    During the Easter period, the weeks of 12 and 19 April, there will be only one issue of the Weekly Bulletin (no. 16-17/2004). Items for publication in this double issue should reach the Publication section or Staff Association, as appropriate, before midday on Tuesday 6 April. Announcements for publication in the next issue (no. 18/2004) should be sent on Tuesday 20 April midday at the latest. Publication Section Tel. 79971

  3. Publication of the Bulletin in 2006

    CERN Multimedia

    2005-01-01

    Deadlines for the submission of announcements The table below lists the 2006 publication dates for the paper version of the Bulletin and the corresponding deadlines for the submission of announcements. Please note that all announcements must be submitted by 12.00 midday on Tuesdays at the latest and that, for organisational reasons, we will no longer be able to accept those which reach us after this deadline. Bulletin publication 2006 Bulletin No. Week number Publication date Submission of announcements (before 12.00 midday) 3-4 Monday 16 January Tuesday 10 January 5-6 Monday 30 January Tuesday 24 January 7-8 Monday 13 February Tuesday 7 February 9-10 Monday 27 February Tuesday 21 February 11-12 Monday 13 March Tuesday 7 March 13-14 Monday 27 March Tuesday 21 March 15-16 Monday 10 April Tuesday 4 April 17-18 Monday 24 April Tuesday 18 April 19-20 Monday 8 May Tuesday 2 May 21-22 Monday 22 May Tuesday 16 May 23-24 Monday 5 June Tuesday 30 May 2...

  4. Publication of the Bulletin in 2006

    CERN Multimedia

    Publications Section, DSU-CO

    2006-01-01

    Deadlines for the submission of announcements The table below lists the 2006 publication dates for the paper version of the Bulletin and the corresponding deadlines for the submission of announcements. Please note that all announcements must be submitted by 12.00 midday on Tuesdays at the latest and that, for organisational reasons, we will no longer be able to accept those which reach us after this deadline. Bulletin publication 2006 Bulletin No. Week number Publication date Submission of announcements (before 12.00 midday) 5-6 Monday 30 January Tuesday 24 January 7-8 Monday 13 February Tuesday 7 February 9-10 Monday 27 February Tuesday 21 February 11-12 Monday 13 March Tuesday 7 March 13-14 Monday 27 March Tuesday 21 March 15-16 Monday 10 April Tuesday 4 April 17-18 Monday 24 April Tuesday 18 April 19-20 Monday 8 May Tuesday 2 May 21-22 Monday 22 May Tuesday 16 May 23-24 Monday 5 June Tuesday 30 May 25-26 Monday 19 June Tuesday 13 June 27-2...

  5. CERN Bulletin publication schedule for 2016

    CERN Multimedia

    2015-01-01

    The table below lists the 2016 publication dates for the CERN Bulletin and the corresponding deadlines for the submission of announcements. Please note that all announcements must be submitted by 12 noon on Tuesdays at the latest.   Bulletin No. (corresponding to the week number) Submission deadline for announcements (before 12 noon) Publication of Bulletin (web version) 3-4 Tuesday 12 January Friday 15 January 5-6 Tuesday 26 January Friday 29 January 7-8 Tuesday 9 February Friday 12 February 9-10 Tuesday 23 February Friday 26 February 11-12 Tuesday 8 March Friday 11 March 13-14 MONDAY 21 March THURSDAY 24 March 15-16 Tuesday 5 April Friday 8 April 17-18-19 Tuesday 19 April Friday 22 April 20-21 Tuesday 10 May Friday 13 May 22-23 Tuesday 24 May Friday 27 May 24-25 Tuesday 7 June Friday 10 June 26-27 Tuesday 21 June Friday 24 June 28-29 Tuesday 5 July Friday 8 July 30-31-32 Tuesday 19 July Friday 22 July 33-34-35 Tuesday 9 August Friday 12 August 3...

  6. CERN Bulletin publication schedule for 2015

    CERN Multimedia

    2014-01-01

    The table below lists the 2015 publication dates for the CERN Bulletin and the corresponding deadlines for the submission of announcements. Please note that all announcements must be submitted by 12 noon on Tuesdays at the latest.   .tftable {font-size:12px;color:#333333;width:100%;border-width: 1px;border-color: #a9a9a9;border-collapse: collapse;} .tftable th {font-size:12px;background-color:#b8b8b8;border-width: 1px;padding: 8px;border-style: solid;border-color: #a9a9a9;text-align:left;} .tftable tr {background-color:#ffffff;} .tftable td {font-size:12px;border-width: 1px;padding: 8px;border-style: solid;border-color: #a9a9a9;} .tftable tr:hover {background-color:#ffff99;} Bulletin No. (corresponding to the week number) Submission deadline for announcements (before 12 noon) Publication of Bulletin (web version) 4-5 Tuesday 13 January Friday 16 January 6-7 Tuesday 26 January Friday 30 January 8-9 Tuesday 10 February Friday 13 February 10-11 Tuesday 24 February ...

  7. Welcome to the new eBulletin!

    CERN Multimedia

    Corinne Pralavorio

    You are now reading one of the new sections of the new eBulletin launched this week. Entitled "What's New", this section will allow us to tell you about important news and events when they occur, without having to wait for a new Bulletin update. So, when the Higgs Boson is discovered, you will be among the first to know! This column will also contain links to the new items included in the weekly update of the electronic Bulletin. Under this section, you will find several other practical sections:"Four Your Eyes Only", presenting a striking photo or a video, "What's on Today", detailing the day's seminars and other events, and "Under the CERN Sky", giving the latest weather information. There is also a list of useful links at the bottom of the column. Concerning your usual section: the "News Articles" can be accessed directly from links on the home page, while other information items are accessible from the relevant menu headings. In addition, you will now find a set of tools at the end of each article, enabli...

  8. Daddy Months

    OpenAIRE

    Volker Meier; Helmut Rainer

    2014-01-01

    We consider a bargaining model in which husband and wife decide on the allocation of time and disposable income. Since her bargaining power would go down otherwise more strongly, the wife agrees to having a child only if the husband also leaves the labor market for a while. The daddy months subsidy enables the couple to overcome a hold-up problem and thereby improves efficiency. However, the same ruling harms cooperative couples and may also reduce welfare in an endogenous taxation framework.

  9. Safety and communication, a winning combination

    CERN Multimedia

    HSE Unit

    2014-01-01

    Since 2013, in line with its mission to support CERN’s proactive communication policy in matters of safety, the HSE unit has been following an annual plan for disseminating information on occupational health and safety and environmental protection.   Safety information designed to underline the importance of prevention is published through a variety of channels: Announcements in the CERN Bulletin, Safety bulletins, notably outlining lessons to be learned in the wake of accidents/incidents occuring at CERN, Safety alerts calling for immediate action, sent by e-mail to the services concerned, Prevention campaigns on the CERN site, Poster campaigns in well frequented public areas. Photo: Christoph Balle. Please heed all prevention messages and apply them in your everyday life. Also, we will be pleased to receive any information or suggestions you may have on safety matters. If you have questions about the HSE unit’s communication activities, please send us an e...

  10. Assessment of ocular hypotensive effect and safety 12 months after changing from an unfixed combination to a latanoprost 0.005% + timolol maleate 0.5% fixed combination.

    Science.gov (United States)

    Inoue, Kenji; Okayama, Ryoko; Higa, Risako; Wakakura, Masato; Tomita, Goji

    2012-01-01

    Latanoprost 0.005% + timolol maleate 0.5% combined eyedrops were recently made available in Japan. We prospectively investigated the intraocular pressure (IOP)-lowering effect, visual preservation effect, and adverse reactions of a one-year administration of this fixed combination. The subjects included 162 eyes from 162 patients diagnosed with either primary open-angle glaucoma or ocular hypertension and using an unfixed combination of latanoprost 0.005% and timolol maleate 0.5%. The unfixed combination was discontinued and replaced with the latanoprost 0.005% + timolol maleate 0.5% fixed combination with no washout period. IOP was measured before (baseline) and 3, 6, 9, and 12 months after the change. The mean deviation value of Humphrey field analysis was compared. Adverse reactions were examined at every follow-up. No significant differences were found between mean IOP values obtained at baseline (mean ± standard deviation, 15.2 ± 3.3 mmHg) 3 months (15.1 ± 3.2 mmHg), 6 months (15.3 ± 3.1 mmHg), 9 months (15.3 ± 3.1 mmHg), and 12 months (15.1 ± 3.2 mmHg) after the change from the unfixed to the fixed combination of eyedrops (P = 0.212). In addition, no significant differences were observed between mean deviation values obtained at baseline (-9.11 ± 6.94 dB) and 12 months (-10.08 ± 7.24 dB) after the change (P = 0.114). Thirty-one patients discontinued the fixed combination within 12 months of replacement, due to an insufficient IOP decrease (20 patients, 12.3%) and adverse reactions (11 patients, 6.8%). Following replacement of two eyedrop medications (latanoprost 0.005% and timolol maleate 0.5%) by one fixed combination (latanoprost 0.005% + timolol maleate 0.5%), IOP and visual field were preserved. However, 20% of the patients discontinued the new treatment because of an insufficient IOP decrease and complaints of adverse reactions.

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  17. Federal Government Electronic Bulletin Boards: An Assessment with Policy Recommendations.

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    Bertot, John Carlo; McClure, Charles R.

    1993-01-01

    Identifies and analyzes federal government electronic bulletin boards; assesses the types of information available to users, including costs and technological access issues; discusses federal information policy; and considers the role of federal bulletin boards in accessing and managing electronic government information. (Contains 29 references.)…

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  2. Bulletin of Materials Science | Indian Academy of Sciences

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    Home; Journals; Bulletin of Materials Science. D K Avasthi. Articles written in Bulletin of Materials Science. Volume 27 Issue 3 June 2004 pp 263-267 Polymers. Electrical properties of ion irradiated polypropylene films · N L Singh Anita Sharma V Shrinet A K Rakshit D K Avasthi · More Details Abstract Fulltext PDF. The effect ...

  3. Bulletin of Materials Science | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Bulletin of Materials Science. V Shrinet. Articles written in Bulletin of Materials Science. Volume 27 Issue 3 June 2004 pp 263-267 Polymers. Electrical properties of ion irradiated polypropylene films · N L Singh Anita Sharma V Shrinet A K Rakshit D K Avasthi · More Details Abstract Fulltext PDF. The effect of ...

  4. Bulletin of Materials Science | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Bulletin of Materials Science. A K Rakshit. Articles written in Bulletin of Materials Science. Volume 27 Issue 3 June 2004 pp 263-267 Polymers. Electrical properties of ion irradiated polypropylene films · N L Singh Anita Sharma V Shrinet A K Rakshit D K Avasthi · More Details Abstract Fulltext PDF. The effect ...

  5. INEL BNCT Program: Volume 5, No. 9. Bulletin, September 1991

    Energy Technology Data Exchange (ETDEWEB)

    Ackermann, A.L. [ed.

    1991-12-31

    This Bulletin presents a summary of accomplishments and highlights of the Idaho National Engineering Laboratory`s (INEL) Boron Neutron Capture Therapy (BNCT) Program for September 1991. This bulletin includes information on the brain tumor and melanoma research programs, Power Burst Facility (PBF) technical support and modifications, PBF operations, and updates to the animal data charts.

  6. Bulletin of Materials Science | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Bulletin of Materials Science. K Chandra. Articles written in Bulletin of Materials Science. Volume 30 Issue 4 August 2007 pp 309-314 Biomaterials. Characteristics of porous zirconia coated with hydroxyapatite as human bones · V V Narulkar S Prakash K Chandra · More Details Abstract Fulltext PDF.

  7. Bulletin of Materials Science | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Bulletin of Materials Science. XIAOWEN ZHANG. Articles written in Bulletin of Materials Science. Volume 37 Issue 4 June 2014 pp 895-902. Structural evolution, electrical and optical properties of AZO films deposited by sputtering ultra-high density target · Jiwen Xu Zupei Yang Hua Wang Xiaowen Zhang.

  8. Bulletin of Materials Science | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Bulletin of Materials Science. KANNAIYAN DINAKARAN. Articles written in Bulletin of Materials Science. Volume 40 Issue 7 December 2017 pp 1455-1462. A sensitive optical sensor based on DNA-labelled Si@SiO 2 core–shell nanoparticle for the detection of Hg 2 + ions in environmental water samples.

  9. Bulletin of Materials Science | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Bulletin of Materials Science. V Bhat. Articles written in Bulletin of Materials Science. Volume 23 Issue 4 August 2000 pp 295-299 Alloys. A test for diffusional coherency strain hypothesis in the discontinuous precipitation in Mg–Al alloy · K T Kashyap C Ramachandra V Bhat B Chatterji · More Details Abstract ...

  10. Bulletin of Materials Science | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Bulletin of Materials Science. AGNIESZKA SOBCZAK-KUPIEC. Articles written in Bulletin of Materials Science. Volume 36 Issue 4 August 2013 pp 755-764. Effect of calcination conditions of pork bone sludge on behaviour of hydroxyapatite in simulated body fluid · Agnieszka Sobczak-Kupiec Zbigniew ...

  11. Bulletin of Materials Science | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Bulletin of Materials Science. SUDHANSHU CHOUDHARY. Articles written in Bulletin of Materials Science. Volume 35 Issue 5 October 2012 pp 713-718. Theoretical study on effect of radial and axial deformation on electron transport properties in a semiconducting Si–C nanotube · Sudhanshu Choudhary ...

  12. Bulletin of Materials Science | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Bulletin of Materials Science. Amarnath. Articles written in Bulletin of Materials Science. Volume 26 Issue 4 June 2003 pp 435-439 Biomaterials. Effect of heat treatments on the hydrogen embrittlement susceptibility of API X-65 grade line-pipe steel · G Ananta Nagu Amarnath T K G Namboodhiri.

  13. Bulletin of Materials Science | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Bulletin of Materials Science. KADARKARAI MURUGAN. Articles written in Bulletin of Materials Science. Volume 40 Issue 7 December 2017 pp 1455-1462. A sensitive optical sensor based on DNA-labelled Si@SiO 2 core–shell nanoparticle for the detection of Hg 2 + ions in environmental water samples.

  14. Bulletin of Materials Science | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Bulletin of Materials Science. YONG J IANG. Articles written in Bulletin of Materials Science. Volume 40 Issue 6 October 2017 pp 1255-1261. Molecular dynamics study on the relaxation properties of bilayered graphene with defects · WEI ZHANG JIU-REN YIN PING ZHANG YAN-HUAI DING YONG J IANG.

  15. Bulletin of Materials Science | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Bulletin of Materials Science. B Swarna Latha. Articles written in Bulletin of Materials Science. Volume 37 Issue 4 June 2014 pp 883-888. Structural, spectroscopic and electrochemical study of V substituted LiTi2(PO4)3 solid electrolyte for lithium-ion batteries · A Venkateswara Rao V Veeraiah A V Prasada ...

  16. Bulletin of Materials Science | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Bulletin of Materials Science. DANUTA OLSZEWSKA. Articles written in Bulletin of Materials Science. Volume 41 Issue 1 February 2018 pp 16. Influence of the conditions of a solid-state synthesis anode material Li 4 Ti 5 O 12 on its electrochemical properties of lithium cells · DANUTA OLSZEWSKA ANNA ...

  17. Bulletin of Materials Science | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Bulletin of Materials Science. B V Radhakrishna Bhat. Articles written in Bulletin of Materials Science. Volume 23 Issue 2 April 2000 pp 109-117 Composites. Optimization of processing parameters for making alumina–partially stabilized zirconia laminated composites · S Deb B V Radhakrishna Bhat.

  18. Bulletin of Materials Science | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Bulletin of Materials Science. S K Biswas. Articles written in Bulletin of Materials Science. Volume 33 Issue 3 June 2010 pp 251-255 Polymers. Effect of substrate roughness on growth of diamond by hot filament CVD · Awadesh K Mallik S R Binu L N Satapathy Chandrabhas Narayana Md Motin Seikh S A ...

  19. Bulletin of Materials Science | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Bulletin of Materials Science. Jadu Samuel. Articles written in Bulletin of Materials Science. Volume 36 Issue 6 November 2013 pp 981-987. Green chemical incorporation of sulphate into polyoxoanions of molybdenum to nano level · Jadu Samuel S Hari Prasad M K Sreedhar · More Details Abstract Fulltext ...

  20. Bulletin of Materials Science | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Bulletin of Materials Science. T K Bhattacharya. Articles written in Bulletin of Materials Science. Volume 26 Issue 7 December 2003 pp 703-706 Cements. Solid state sintering of lime in presence of La2O3 and CeO2 · T K Bhattacharya A Ghosh H S Tripathi S K Das · More Details Abstract Fulltext PDF.

  1. Archives: Bulletin of Animal Health and Production in Africa

    African Journals Online (AJOL)

    Items 1 - 50 of 60 ... Archives: Bulletin of Animal Health and Production in Africa. Journal Home > Archives: Bulletin of Animal Health and Production in Africa. Log in or Register to get access to full text downloads. Username, Password, Remember me, or Register · Journal Home · ABOUT THIS JOURNAL · Advanced Search ...

  2. Archives: Bulletin of the Chemical Society of Ethiopia

    African Journals Online (AJOL)

    Items 1 - 50 of 74 ... Archives: Bulletin of the Chemical Society of Ethiopia. Journal Home > Archives: Bulletin of the Chemical Society of Ethiopia. Log in or Register to get access to full text downloads. Username, Password, Remember me, or Register · Journal Home · ABOUT THIS JOURNAL · Advanced Search · Current Issue ...

  3. Bulletin of the Chemical Society of Ethiopia: About this journal

    African Journals Online (AJOL)

    Bulletin of the Chemical Society of Ethiopia: About this journal. Journal Home > Bulletin of the Chemical Society of Ethiopia: About this journal. Log in or Register to get access to full text downloads. Username, Password, Remember me, or Register · Journal Home · ABOUT THIS JOURNAL · Advanced Search · Current Issue ...

  4. Bulletin of Materials Science | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Bulletin of Materials Science. Dong Zhang. Articles written in Bulletin of Materials Science. Volume 34 Issue 1 February 2011 pp 25-28. Aqueous colloids of graphene oxide nanosheets by exfoliation of graphite oxide without ultrasonication · Tian-You Zhang Dong Zhang · More Details Abstract Fulltext PDF.

  5. Bulletin of Materials Science | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Bulletin of Materials Science. V Ganesan. Articles written in Bulletin of Materials Science. Volume 28 Issue 6 October 2005 pp 609-615 Thin Films. Structural morphology of amorphous conducting carbon film · P N Vishwakarma V Prasad S V Subramanyam V Ganesan · More Details Abstract Fulltext PDF.

  6. Bulletin of Materials Science | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Bulletin of Materials Science. ISABEL HERRMANN. Articles written in Bulletin of Materials Science. Volume 41 Issue 1 February 2018 pp 18. Advanced nanofibrous textile-based dressing material for treating chronic wounds · ISABEL HERRMANN EKO SUPRIYANTO SARAVANA KUMAR JAGANATHAN A ...

  7. Bulletin of Materials Science | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Bulletin of Materials Science. M Mandal. Articles written in Bulletin of Materials Science. Volume 37 Issue 4 June 2014 pp 743-752. Porous copper template from partially spark plasma-sintered Cu–Zn aggregate via dezincification · M Mandal D Singh Gouthama B S Murty S Sangal K Mondal · More Details ...

  8. Bulletin of Materials Science | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Bulletin of Materials Science. D K Kharat. Articles written in Bulletin of Materials Science. Volume 28 Issue 5 August 2005 pp 453-455 Ceramics and Glasses. Characterization and microstructure of porous lead zirconate titanate ceramics · B Praveenkumar H H Kumar D K Kharat · More Details Abstract ...

  9. Bulletin of Materials Science | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Bulletin of Materials Science. Hui Shen. Articles written in Bulletin of Materials Science. Volume 30 Issue 2 April 2007 pp 101-104 Single Crystals. Piezoelectric properties of Sr3Ga2Ge4O14 single crystals · Anhua Wu Jiayue Xu Juan Zhou Hui Shen · More Details Abstract Fulltext PDF. A new piezoelectric ...

  10. Bulletin of Materials Science | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Bulletin of Materials Science. Anhua Wu. Articles written in Bulletin of Materials Science. Volume 27 Issue 4 August 2004 pp 333-336 Crystal Growth. Bridgman growth and defects of Nd : Sr3Ga2Ge4O14 laser crystals · Jiaxuan Ding Anhua Wu Jiayue Xu · More Details Abstract Fulltext PDF.

  11. Bulletin of Materials Science | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Bulletin of Materials Science. G Prasad. Articles written in Bulletin of Materials Science. Volume 23 Issue 5 October 2000 pp 431-437 High T c Superconductors. Studies on electrical properties of SrBi4Ti4–3Fe4O15 · N Venkat Ramulu G Prasad S V Suryanarayana T Bhima Sankaram · More Details ...

  12. Bulletin of Materials Science | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Bulletin of Materials Science. S Muthulakshmi. Articles written in Bulletin of Materials Science. Volume 37 Issue 7 December 2014 pp 1575-1582. Effect of temperature on the AC impedance of protein and carbohydrate biopolymers · S Muthulakshmi S Iyyapushpam D Pathinettam Padiyan · More Details ...

  13. Bulletin of Materials Science | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Bulletin of Materials Science. A K Sahu. Articles written in Bulletin of Materials Science. Volume 32 Issue 3 June 2009 pp 285-294. Nafion and modified-Nafion membranes for polymer electrolyte fuel cells: An overview · A K Sahu S Pitchumani P Sridhar A K Shukla · More Details Abstract Fulltext PDF.

  14. Bulletin of Materials Science | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Bulletin of Materials Science. N L Singh. Articles written in Bulletin of Materials Science. Volume 27 Issue 3 June 2004 pp 263-267 Polymers. Electrical properties of ion irradiated polypropylene films · N L Singh Anita Sharma V Shrinet A K Rakshit D K Avasthi · More Details Abstract Fulltext PDF. The effect ...

  15. Bulletin of Materials Science | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Bulletin of Materials Science. Sejal Shah. Articles written in Bulletin of Materials Science. Volume 30 Issue 5 October 2007 pp 477-480 Polymers. Study of microhardness and electrical properties of proton irradiated polyethersulfone (PES) · Nilam Shah Dolly Singh Sejal Shah Anjum Qureshi N L Singh K P ...

  16. Bulletin of Materials Science | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Bulletin of Materials Science. S Prasannakumar. Articles written in Bulletin of Materials Science. Volume 24 Issue 5 October 2001 pp 535-538 Polymers. Interpenetrating polymer networks based on polyol modified castor oil polyurethane and poly(2-hydroxyethylmethacrylate): Synthesis, chemical, ...

  17. Bulletin of Materials Science | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Bulletin of Materials Science. K V Shah. Articles written in Bulletin of Materials Science. Volume 26 Issue 7 December 2003 pp 715-720 Glasses and Ceramics. Preparation and studies of some thermal, mechanical and optical properties of Al2O3(1 – )NaPO3 glass system · K V Shah V Sudarsan M ...

  18. Bulletin of Materials Science | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Bulletin of Materials Science. Ganesh Sanjeev. Articles written in Bulletin of Materials Science. Volume 33 Issue 3 June 2010 pp 191-196 Thin Films and Nanomatter. Dielectric properties of electron irradiated PbZrO3 thin films · Shetty Aparna V M Jali Ganesh Sanjeev Jayanta Parui S B Krupanidhi.

  19. Bulletin of Materials Science | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Bulletin of Materials Science. LING YANG. Articles written in Bulletin of Materials Science. Volume 36 Issue 3 June 2013 pp 389-393. Effects of Bi doping on dielectric and ferroelectric properties of PLBZT ferroelectric thin films synthesized by sol–gel processing · Hua Wang Li Liu Ji-Wen Xu Chang-Lai Yuan ...

  20. Qi Liu - Bulletin of Materials Science | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Bulletin of Materials Science. QI LIU. Articles written in Bulletin of Materials Science. Volume 34 Issue 2 April 2011 pp 183-189. Study of structural transformations and phases formation upon calcination of Zn–Ni–Al hydrotalcite nanosheets · Zhanshuang Li Yanchao Song Jun Wang Qi Liu Piaoping Yang ...

  1. Bulletin of Materials Science | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Bulletin of Materials Science. A S Singha. Articles written in Bulletin of Materials Science. Volume 31 Issue 1 February 2008 pp 7-13 Polymers. Pressure induced graft-co-polymerization of acrylonitrile onto Saccharum cilliare fibre and evaluation of some properties of grafted fibre · A S Singha Anjali Shama ...

  2. Bulletin of Materials Science | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Bulletin of Materials Science. L C GUPTA. Articles written in Bulletin of Materials Science. Volume 40 Issue 6 October 2017 pp 1121-1125. High-pressure studies of superconductivity in BiO 0.75 F 0.25 BiS 2 · ZEBA HAQUE GOHIL S THAKUR GANESAN KALAI SELVAN SONACHALAM ARUMUGAM L C ...

  3. Bulletin of Materials Science | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Bulletin of Materials Science. H P Sachin. Articles written in Bulletin of Materials Science. Volume 30 Issue 1 February 2007 pp 57-63 Electrochemistry. Polynitroaniline as brightener for zinc–nickel alloy plating from non-cyanide sulphate bath · H P Sachin Ganesha Achary Y Arthoba Naik T V Venkatesha.

  4. Bulletin of Materials Science | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Bulletin of Materials Science. M Petrič. Articles written in Bulletin of Materials Science. Volume 34 Issue 1 February 2011 pp 113-119. Performance of waterborne acrylic surface coatings on wood impregnated with Cu-ethanolamine preservatives · M Humar M Pavlič D Žlindra M Tomažič M Petrič.

  5. Bulletin of Materials Science | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Bulletin of Materials Science. M Hafez. Articles written in Bulletin of Materials Science. Volume 33 Issue 2 April 2010 pp 149-155 Polymers. Influence of granular strontium chloride as additives on some electrical and mechanical properties for pure polyvinyl alcohol · A B Elaydy M Hafez · More Details ...

  6. Immunogenicity and Safety of a Trivalent Inactivated Influenza Vaccine in Children 6 Months to 17 Years of Age, Previously Vaccinated with an AS03-Adjuvanted A(H1N1)Pdm09 Vaccine: Two Open-label, Randomized Trials.

    Science.gov (United States)

    Vesikari, Timo; Richardus, Jan Hendrik; Berglund, Johan; Korhonen, Tiina; Flodmark, Carl-Erik; Lindstrand, Ann; Silfverdal, Sven Arne; Bambure, Vinod; Caplanusi, Adrian; Dieussaert, Ilse; Roy-Ghanta, Sumita; Vaughn, David W

    2015-07-01

    During the influenza pandemic 2009-2010, an AS03-adjuvanted A(H1N1)pdm09 vaccine was used extensively in children 6 months of age and older, and during the 2010-2011 influenza season, the A(H1N1)pdm09 strain was included in the seasonal trivalent inactivated influenza vaccine (TIV) without adjuvant. We evaluated the immunogenicity and safety of TIV in children previously vaccinated with the AS03-adjuvanted A(H1N1)pdm09 vaccine. Healthy children were randomized (1:1) to receive TIV or a control vaccine. Children were aged 6 months to 9 years (n = 154) and adolescents 10-17 years (n = 77) when they received AS03-adjuvanted A(H1N1)pdm09 vaccine at least 6 months before study enrolment. Hemagglutination inhibition (HI) and neutralizing antibody responses against the A(H1N1)pdm09 strain were evaluated before (day 0) and at day 28 and month 6 after study vaccination. Reactogenicity was assessed during the 7 day postvaccination period, and safety was assessed for 6 months. At day 0, >93.9% of all children had HI titers ≥1:40 for the A(H1N1)pdm09 strain, which increased to 100% at both day 28 and month 6 in the TIV group. Between days 0 and 28, HI antibody geometric mean titers against A(H1N1)pdm09 increased by 9-fold and 4-fold in children 6 months to 9 years of age and 10-17 years of age, respectively. AS03-adjuvanted A(H1N1)pdm09 vaccine-induced robust immune responses in children that persisted into the next season, yet were still boosted by TIV containing A(H1N1)pdm09. The reactogenicity and safety profile of TIV did not appear compromised by prior receipt of AS03-adjuvanted A(H1N1)pdm09 vaccine.

  7. Efficacy, tolerability, and safety of aripiprazole once-monthly versus other long-acting injectable antipsychotic therapies in the maintenance treatment of schizophrenia: a mixed treatment comparison of double-blind randomized clinical trials.

    Science.gov (United States)

    Majer, Istvan M; Gaughran, Fiona; Sapin, Christophe; Beillat, Maud; Treur, Maarten

    2015-01-01

    Treatment with long-acting injectable (LAI) antipsychotic medication is an important element of relapse prevention in schizophrenia. Recently, the intramuscular once-monthly formulation of aripiprazole received marketing approval in Europe and the United States for schizophrenia. This study aimed to compare aripiprazole once-monthly with other LAI antipsychotics in terms of efficacy, tolerability, and safety. A systematic literature review was conducted to identify relevant double-blind randomized clinical trials of LAIs conducted in the maintenance treatment of schizophrenia. MEDLINE, MEDLINE In-Process, Embase, the Cochrane Library, PsycINFO, conference proceedings, clinical trial registries, and the reference lists of key review articles were searched. The literature search covered studies dating from January 2002 to May 2013. Studies were required to have ≥24 weeks of follow-up. Patients had to be stable at randomization. Studies were not eligible for inclusion if efficacy of acute and maintenance phase treatment was not reported separately. Six trials were identified (0.5% of initially identified studies), allowing comparisons of aripiprazole once-monthly, risperidone LAI, paliperidone palmitate, olanzapine pamoate, haloperidol depot, and placebo. Data extracted included study details, study duration, the total number of patients in each treatment arm, efficacy, tolerability, and safety outcomes. The efficacy outcome contained the number of patients that experienced a relapse, tolerability outcomes included the number of patients that discontinued treatment due to treatment-related adverse events (AEs), and that discontinued treatment due to reasons other than AEs (e.g., loss to follow-up). Safety outcomes included the incidence of clinically relevant weight gain and extrapyramidal symptoms. Data were analyzed by applying a mixed treatment comparison competing risks model (efficacy) and using binary models (safety). There was no statistically significant

  8. Immunogenicity and safety of an inactivated hepatitis A vaccine when coadministered with Diphtheria-tetanus-acellular pertussis and haemophilus influenzae type B vaccines in children 15 months of age.

    Science.gov (United States)

    Trofa, Andrew F; Klein, Nicola P; Paul, Ian M; Michaels, Marian G; Goessler, Mary; Chandrasekaran, Vijayalakshmi; Blatter, Mark

    2011-09-01

    This study (NCT00197236) evaluated the safety and immunogenicity of a hepatitis A virus (HAV) vaccine when coadministered with diphtheria-tetanus-acellular pertussis (DTaP) and Haemophilus influenzae type b (Hib) vaccines in children 15 months of age. This was an open-labeled, multicenter study with healthy subjects enrolled and randomized (1:1:1) into 3 treatment groups. A total of 394 subjects received the first study vaccinations at 15 months of age. Group HAV (N = 135) received 2 doses of HAV vaccine 6 to 9 months apart. Group HAV+DTaP+Hib (N = 127) received HAV vaccine coadministered with DTaP and Hib vaccines and the second dose of HAV vaccine, 6 to 9 months later. Group DTaP+Hib→HAV (N = 132) received the DTaP and Hib vaccines at 15 months of age, followed by HAV vaccine 30 days later and the second dose of HAV vaccine 7 to 10 months after the DTaP+Hib vaccines. Immune responses were evaluated before the first study vaccination and 30 days after each vaccine dose. Solicited, unsolicited, and serious adverse events were collected. After 2 doses of the HAV vaccine, all subjects in the 3 groups were seropositive. The geometric mean concentration of anti-HAV antibodies ranged between 1625.1 and 1904.4 mIU/mL. Coadministration of the 3 vaccines did not impact immunogenicity of the HAV, DTaP, or Hib vaccines. Vaccines were well tolerated in all groups. A 2-dose schedule of HAV vaccine was well tolerated and immunogenic when administered to children starting at 15 months of age. Immune responses to the DTaP or Hib vaccines were similar whether they were administered alone or were coadministered with the HAV vaccine.

  9. Efficacy and safety of a hyaluronic acid filler in subjects treated for correction of midface volume deficiency: a 24 month study

    Directory of Open Access Journals (Sweden)

    Callan P

    2013-03-01

    Full Text Available Peter Callan,1 Greg J Goodman,2 Ian Carlisle,3 Steven Liew,4 Peter Muzikants,5 Terrence Scamp,6 Michael B Halstead,7 John D Rogers71Peter Callan Plastic Surgery, Geelong, VIC, 2Dermatology Institute of Victoria, South Yarra, VIC, 3Erase Skin Rejuvenation Specialists, Malvern, VIC, 4Shape Clinic and Medispa, Darlinghurst, NSW, 5Ada Cosmetic Medicine, Glebe, NSW, 6Esteem Beauty and Day Spa, Main Beach, QLD, 7Allergan Medical Affairs, Gordon, ACT, AustraliaBackground: Hyaluronic acid (HA fillers are an established intervention for correcting facial volume deficiency. Few studies have evaluated treatment outcomes for longer than 6 months. The purpose of this study was to determine the durability of an HA filler in the correction of midface volume deficiency over 24 months, as independently evaluated by physician investigators and subjects.Methods: Subjects received treatment with Juvéderm™ Voluma™ to the malar area, based on the investigators' determination of baseline severity and aesthetic goals. The treatment was administered in one or two sessions over an initial 4-week period. Supplementary treatment was permissible at week 78, based on protocol-defined criteria. A clinically meaningful response was predefined as at least a one-point improvement on the MidFace Volume Deficit Scale (MFVDS and on the Global Aesthetic Improvement Scale (GAIS.Results: Of the 103 subjects enrolled, 84% had moderate or significant volume deficiency at baseline. At the first post-treatment evaluation (week 8, 96% were documented to be MFVDS responders, with 98% and 100% graded as GAIS responders when assessed by the subjects and investigators, respectively. At week 78, 81.7% of subjects were still MFVDS responders, with 73.2% and 78.1% being GAIS responders, respectively. Seventy-two subjects completed the 24-month study, of whom 45 did not receive supplementary Voluma™ at week 78. Forty-three of the 45 (95.6% subjects were MFVDS responders, with 82.2% and 91

  10. Real-world variability in ranibizumab treatment and associated clinical, quality of life, and safety outcomes over 24 months in patients with neovascular age-related macular degeneration: the HELIOS study

    Directory of Open Access Journals (Sweden)

    Rakic JM

    2013-09-01

    Full Text Available Jean-Marie Rakic,1 Anita Leys,2 Heidi Brié,3 Kris Denhaerynck,4 Christy Pacheco,4 Stefaan Vancayzeele,3 Christine Hermans,3 Karen MacDonald,4 Ivo Abraham4,5 1Department of Ophthalmology, Centre Hospitalier Universitaire de Liège, Site du Sart Tilman, Liège, Belgium; 2Leuven University Eye Hospital, Leuven, Belgium; 3Novartis Pharma, Vilvoorde, Belgium; 4Matrix45, Tucson, AZ, USA; 5Center for Health Outcomes and Pharmacoeconomic Research, University of Arizona, Tucson, AZ, USA Introduction: The aim of this study was to examine ranibizumab treatment patterns in "real-world" practice and clinical settings, as well as to assess quality of life outcomes over a 24-month period. Materials and methods: This was a prospective, observational, multicenter, open-label study of 0.5 mg of ranibizumab administered intravitreally. Patients were followed over 24 ± 3 months with intermediate data points at 6 ± 2 months and 12 ± 2 months, and a limited data point at 2.5 ± 1 month that coincided with the end of the loading phase. Outcomes included visual acuity (Early Treatment Diabetic Retinopathy Study, visual function (National Eye Institute Visual Function Questionnaire-25 [NEI VFQ-25], quality of life (Health Utilities Index Mark III [HUI3], and safety. Results: A total of 267 patients with wet age-related macular degeneration (mean ± standard deviation [SD] age = 78.5 ± 7.3 years; 62.4% were female; 34.5% with dual eye involvement; 74.9% were treatment-naïve were treated (309 eyes were treated. The mean ± SD Early Treatment Diabetic Retinopathy Study score at baseline was 56.3 ± 14.3 letters. The mean ± SD number of injections over 24 months was 7.6 ± 4.1, including 2.5 ± 0.7 and 5.9 ± 3.6 during the loading and maintenance phases, respectively, with corresponding treatment intervals of 4.8 ± 1.4 weeks and 11.5 ± 9.5 weeks, respectively. Improvements in visual acuity over baseline were reached at 2.5 months and maintained at 6 months (both P

  11. An Online, Moderated Peer-to-Peer Support Bulletin Board for Depression: User-Perceived Advantages and Disadvantages.

    Science.gov (United States)

    Griffiths, Kathleen Margaret; Reynolds, Julia; Vassallo, Sara

    2015-01-01

    Online, peer-to-peer support groups for depression are common on the World Wide Web and there is some evidence of their effectiveness. However, little is known about the mechanisms by which Internet support groups (ISGs) might work. This study aimed to investigate consumer perceptions of the benefits and disadvantages of online peer-to-peer support by undertaking a content analysis of the spontaneous posts on BlueBoard, a well-established, moderated, online depression bulletin board. The research set comprised all posts on the board (n=3645) for each of 3 months selected at 4 monthly intervals over 2011. The data were analyzed using content analysis and multiple coders. A total of 586 relevant posts were identified, 453 (77.3%) reporting advantages and 133 (22.7%) reporting disadvantages. Positive personal change (335/453, 74.0%) and valued social interactions and support (296/453, 65.3%) emerged as perceived advantages. Other identified benefits were valued opportunities to disclose/express feelings or views (29/453, 6.4%) and advantages of the BlueBoard environment (45/453, 9.9%). Disadvantages were negative personal change (50/133, 37.6%), perceived disadvantages of board rules/moderation (42/133, 31.6%), unhelpful social interactions/contact with other members (40/133, 30.1%), and technical obstacles to using the board (14/133, 10.5%). Consumers value the opportunity to participate in an online mutual support group for mental health concerns. Further research is required to better understand how and if these perceived advantages translate into positive outcomes for consumers, and whether the perceived disadvantages of such boards can be addressed without compromising the safety and positive outcomes of the board.

  12. Sanitation & Safety for Child Feeding Programs.

    Science.gov (United States)

    Florida State Dept. of Health and Rehabilitative Services, Tallahassee.

    In the interest of promoting good health, sanitation, and safety practices in the operation of child feeding programs, this bulletin discusses practices in personal grooming and wearing apparel; the purchasing, storage, handling, and serving of food; sanitizing equipment and utensils; procedures to follow in case of a food poisoning outbreak; some…

  13. IMMUNOGENICITY AND SAFETY OF QUINVAXEM® (DIPHTHERIA, TETANUS, WHOLE-CELL PERTUSSIS, HEPATITIS B AND HAEMOPHILUS INFLUENZAE TYPE B VACCINE) GIVEN TO VIETNAMESE INFANTS AT 2 TO 4 MONTHS OF AGE.

    Science.gov (United States)

    Huu, Tran Ngoc; Phuong, Nguyen Thi Minh; Toan, Nguyen Trong; Thang, Ho Vinh

    2015-07-01

    Vietnam plans to replace the routine childhood diphtheria, pertussis and tetanus combination (DPT) vaccine with a pentavalent vaccine. The present study was performed to assess the immunogenicity and safety of the combined diphtheria, tetanus, whole-cell pertussis, hepatitis B (HepB), and Haemophilus influenzae type b (Hib) (DTwP-HepB-Hib) Quinvaxem® vaccine in children. A total of 131 infants received the Quinvaxem® vaccine at 2, 3 and 4 months. Antibody levels were measured at baseline, at one month after the third injection and one year after the first injection. Seroprotection rates were high for each vaccine antigen at one month after the third dose: 93.1% for diphtheria, 98.5% for tetanus, 99.2% for pertussis (seroconversion rate), 93.1% for HepB, and 100% for Hib (anti-PRP ≥ 0.15 µg/ml). The rate of children with protective antibodies persisting at one year after the first dose was 88.4% for diphtheria, 49.6% for pertussis, 82.2% for tetanus, 76.7% for HepB and 97.7% for Hib (anti-PRP ≥ 0.15 µg/ml). The Quinvaxem® vaccine was well tolerated and has a low rate of adverse events. Quinvaxem® given at 2, 3 and 4 months of age was immunogenic and safe for primary immunization among infants in Vietnam.

  14. 77 FR 26822 - Pipeline Safety: Verification of Records

    Science.gov (United States)

    2012-05-07

    ... DEPARTMENT OF TRANSPORTATION Pipeline and Hazardous Materials Safety Administration [Docket No. PHMSA-2012-0068] Pipeline Safety: Verification of Records AGENCY: Pipeline and Hazardous Materials... issuing an Advisory Bulletin to remind operators of gas and hazardous liquid pipeline facilities to verify...

  15. Publication of a double issue of the Bulletin at Easter

    CERN Multimedia

    Publications Section

    2005-01-01

    During the Easter period, there will be a single issue of the Bulletin (No. 12-13/2005) covering the weeks of 21 and 28 March. The deadline for articles to appear in this double issue, both in the publications section and in the Staff Association's pages, will be midday on Tuesday, 15 March. No Bulletin will be distributed on 28 March. The deadline for articles to appear in the following issue of the Bulletin, No. 14/2005, will be midday on Tuesday 29 March. Publications Section DSU-CO Tel. 79971

  16. Publication of a double issue of the Bulletin at Easter

    CERN Document Server

    Publications Section

    2005-01-01

    During the Easter period, there will be a single issue of the Bulletin (No. 12-13/2005) covering the weeks of 21 and 28 March. The deadline for articles to appear in this double issue, both in the publications section and in the Staff Association's pages, will be midday on Tuesday, 15 March. No Bulletin will be distributed on 28 March. The deadline for articles to appear in the following issue of the Bulletin, No. 14/2005, will be midday on Tuesday 29 March. Publications Section SG/CO Tel. 79971

  17. Monthly variation in the Bioaccumulation of heavy metals and other safety issues in some marine and fresh water fish species in Ghana

    International Nuclear Information System (INIS)

    Arthur, W.

    2014-07-01

    Fish is one of the major sources of animal protein in Ghana and the fisheries industry is vital to the economy of the country. Unfortunately, most of the aquatic systems in Ghana are being polluted with domestic and industrial wastes which results in bioaccumulation of heavy metals in fish species. The traditional method for preserving fish in the country is by hot smoking or smoke drying, through freezing may be preferred where facilities are available. The presence of high levels of heavy metals in both fresh and smoked fish as well as other fish products is a matter of public health concern in Ghana. Variations in the level of bioaccumulation of heavy metals in both fresh and smoked marine fish, Sebastes marinus (red fish) and fresh water fish, Oreochromis niloticus (tilapia) caught off the coast of James Town in Accra and from the Volta river at Kpong respectively were monitored monthly from September 2013 to March 2014. Extension of two shelf life of the smoked fish species by gamma irradiation was also studied during 4 weeks of low temperature (5± 1 C ) storage by refrigeration. The total concentration of Iron (Fe), Zinc (Zn), Copper (Cu), Magnesium (Mg), Manganese (Mn), Cobalt (Co), Cadmium (Cd), Chromium (Cr), Arsenic (As) and Mercury (Hg) in the fish species as well as in their muscles, gills and bones were determined by Flame or Hydride Generation Atomic Absorption Spectrophotometry. The moisture content, pH, sensory analysis and population of aerobic mesophiles (on PCA), yeast and moulds (on OGYE), Escherichia coli (on EMB), Staphylococcus aureus (on BPA) and Salmonella (on XLD) in fresh fish, and smoked fish after treatment with 1, 2 and 3kGy of gamma irradiation and during storage were determined. Four patterns in the bioaccumulation of heavy metals in both Sebastes marinus and Oreochromis niloticus were observed over the 6 months monitoring period. Fe, Cu, Co and Cr accumulated heavily in the fish species during September and October after which the

  18. Assessment of Microbiological Safety and Quality of Marinades Used To Treat Beef and That Were Collected over a 12-Month Period from Specialty Retailers Near Raleigh, North Carolina.

    Science.gov (United States)

    Jung, Yangjin; Rupert, Christopher L; Chapman, Benjamin; Porto Fett, Anna C S; Luchansky, John B

    2018-02-23

    In total, 115 marinade samples (58 fresh marinades and 57 spent marinades) were collected over 12 months from specialty retailers (four individual stores) near Raleigh, NC. These marinades were screened for total mesophilic aerobic plate count (M-APC), total psychrotrophic aerobic plate count (P-APC), and Enterobacteriaceae. These marinades were also screened for the seven regulated serogroups of Shiga toxin-producing Escherichia coli. Stores A and B used immersion to marinade raw beef cuts, whereas stores C-1 and C-2 used vacuum tumbling. In general, marinade temperatures at the stores ranged from 1.8 to 6.6°C, and beef cuts were marinated from a few minutes to up to 3 days. Regardless of the process used to marinade meat, levels of M-APC and P-APC in fresh marinades ranged from 3.4 to 4.7 and 1.4 to 1.8 log CFU/mL, respectively, whereas Enterobacteriaceae were not detected in any fresh marinades, even after enrichment. However, levels of M-APC, P-APC, and Enterobacteriaceae in spent marinades collected from stores C-1 and C-2 (ca. 3.6 to 7.1 log CFU/mL) were significantly higher ( P B (ca. ≤0.7 to 4.9 log CFU/mL). None of the 115 marinade samples tested positive for Shiga toxin-producing E. coli by using a BAX system real-time PCR assay. No significant ( P > 0.05) association was observed between microbial levels (i.e., M-APC, P-APC, and Enterobacteriaceae) and the temperature or duration of the marination process. Levels of M-APC, P-APC, and Enterobacteriaceae in spent marinades were significantly affected by the marination method ( P < 0.05), with levels, in general, being higher in marinades used for tumbling. Thus, retailers must continue to keep marinade solutions and meat at a safe temperature (i.e., ≤4°C) and to properly and frequently sanitize the equipment and environment in both the processing area and deli case.

  19. EffiCiency and Safety of an eLectronic cigAreTte (ECLAT as tobacco cigarettes substitute: a prospective 12-month randomized control design study.

    Directory of Open Access Journals (Sweden)

    Pasquale Caponnetto

    Full Text Available Electronic cigarettes (e-cigarettes are becoming increasingly popular with smokers worldwide. Users report buying them to help quit smoking, to reduce cigarette consumption, to relieve tobacco withdrawal symptoms, and to continue having a 'smoking' experience, but with reduced health risks. Research on e-cigarettes is urgently needed in order to ensure that the decisions of regulators, healthcare providers and consumers are based on science. Methods ECLAT is a prospective 12-month randomized, controlled trial that evaluates smoking reduction/abstinence in 300 smokers not intending to quit experimenting two different nicotine strengths of a popular e-cigarette model ('Categoria'; Arbi Group Srl, Italy compared to its non-nicotine choice. GroupA (n = 100 received 7.2 mg nicotine cartridges for 12 weeks; GroupB (n = 100, a 6-week 7.2 mg nicotine cartridges followed by a further 6-week 5.4 mg nicotine cartridges; GroupC (n = 100 received no-nicotine cartridges for 12 weeks. The study consisted of nine visits during which cig/day use and exhaled carbon monoxide (eCO levels were measured. Smoking reduction and abstinence rates were calculated. Adverse events and product preferences were also reviewed.Declines in cig/day use and eCO levels were observed at each study visits in all three study groups (p<0.001 vs baseline, with no consistent differences among study groups. Smoking reduction was documented in 22.3% and 10.3% at week-12 and week-52 respectively. Complete abstinence from tobacco smoking was documented in 10.7% and 8.7% at week-12 and week-52 respectively. A substantial decrease in adverse events from baseline was observed and withdrawal symptoms were infrequently reported during the study. Participants' perception and acceptance of the product under investigation was satisfactory.In smokers not intending to quit, the use of e-cigarettes, with or without nicotine, decreased cigarette consumption and elicited enduring tobacco

  20. Volcanology Section Bulletin. French Geologic Society; Bulletin de la Section de Volcanologie. Societe Geologique de France

    Energy Technology Data Exchange (ETDEWEB)

    Boudon, G [I.P.G.P. - Observatoire Volcanologique, 75 - Paris (France); Gourgaud, A [Universite Blaise Pascal, 63 - Clermont Ferrand (France); Soler, E [Universite Paris 6, Paris (France)

    1997-12-31

    This issue of the Volcanology Section Bulletin is a compilation of abstracts from the meeting the section of April, 2 1996 about the active volcanism of Central America and Mexico. The abstracts selected in this issue report on measurements of uranium, thorium and radium isotopes disequilibrium in lava, and radon fluctuations in volcanic gases. One abstract reports on new {sup 14}C datings on avalanche debris. (J.S.).

  1. Volcanology Section Bulletin. French Geologic Society; Bulletin de la Section de Volcanologie. Societe Geologique de France

    Energy Technology Data Exchange (ETDEWEB)

    Boudon, G. [I.P.G.P. - Observatoire Volcanologique, 75 - Paris (France); Gourgaud, A. [Universite Blaise Pascal, 63 - Clermont Ferrand (France); Soler, E. [Universite Paris 6, Paris (France)

    1996-12-31

    This issue of the Volcanology Section Bulletin is a compilation of abstracts from the meeting the section of April, 2 1996 about the active volcanism of Central America and Mexico. The abstracts selected in this issue report on measurements of uranium, thorium and radium isotopes disequilibrium in lava, and radon fluctuations in volcanic gases. One abstract reports on new {sup 14}C datings on avalanche debris. (J.S.).

  2. Bulletin of the Chemical Society of Ethiopia: Submissions

    African Journals Online (AJOL)

    Journal Home > About the Journal > Bulletin of the Chemical Society of Ethiopia: Submissions ... All classes of manuscripts must represent substantial original work and must not ... Each reference should be given a separate reference number.

  3. Bulletin of Materials Science | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Bulletin of Materials Science; Volume 33; Issue 1. Structure, optical and thermal decomposition characters of LDPE graft copolymers synthesized by gamma irradiation ... Keywords. Gamma irradiation; graft copolymerization; spectroscopic analysis; XRD; kinetics of thermal decomposition; activation energy.

  4. Nuclear Knowledge Management e-Bulletin, April 2014

    International Nuclear Information System (INIS)

    2014-04-01

    Since we issued our last e-Bulletin in January, we have held several very interesting and productive meetings with Member State representatives related to various initiatives in knowledge management, education and capacity building. We have highlighted some of them in this issue of our e-Bulletin. You will also notice the shorter format of this e-bulletin. This is in response to feedback from our readers, who have suggested we issue a more condensed e-bulletin, and issue it more often. As nuclear knowledge management is a relevant issue in most areas of the nuclear energy sector, the NKM Section is continually expanding cooperation with other departments and sections within the IAEA and you will see this reflected in our programme activities

  5. Bulletin of Materials Science | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    The Bulletin of Materials Science began in the year 1979. ... one of the world's leading interactive databases of high quality STM journals, book series, books, reference works and online archives collection. ... Sadashivanagar, P.B. No. 8005 ...

  6. Triterpenes from the resin of Boswellia neglecta | Dekebo | Bulletin ...

    African Journals Online (AJOL)

    Bulletin of the Chemical Society of Ethiopia. Journal Home · ABOUT THIS JOURNAL · Advanced Search · Current Issue · Archives · Journal Home > Vol 16, No 1 (2002) >. Log in or Register to get access to full text downloads.

  7. Use of electronic bulletin boards for environmental management

    International Nuclear Information System (INIS)

    Kumar, A.; Rao, H.G.

    1991-01-01

    As a result of changes to existing environmental protection legislation, and the numerous changes to existing regulations that continually take place, environmental managers need updated information on federal mandated programs and regulation, approved and other mathematical models, control technologies, acceptable measurement techniques and continuing education courses. The US Environmental Protection Agency (EPA) is providing help to state and local air pollution control agencies, the regulated community, consultants and the general public through electronic bulletin boards. Each bulletin board (BB) uses data base management system and communication technology to provide access to information on several specific topics of interest to the environmental manager. This review discusses nine bulletin board systems available to the public from the EPA. Several alternative bulletin board systems are also available and will be discussed in future columns

  8. Bulletin of Materials Science | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Bulletin of Materials Science; Volume 39; Issue 7 ... pulse electrodeposition with ultrasound agitation from nickelWatts-type bath. ... The results showed that wear resistance increased with increase in duty cycle and frequency.

  9. Bulletin of Materials Science | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Bulletin of Materials Science; Volume 34; Issue 4 ... has a dielectric anomaly of ferroelectric to paraelectric type at 198°C, and exhibits ... that the compound has negative temperature coefficient of resistance (NTCR) behaviour.

  10. Bulletin of Materials Science | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Bulletin of Materials Science. LI-XIA YANG. Articles written in Bulletin of Materials Science. Volume 34 Issue 2 April 2011 pp 233-237. Shape control synthesis of low-dimensional calcium sulfate · Li-Xia Yang Yan-Feng Meng Ping Yin Ying-Xia Yang Ying-Ying Tang Lai-Fen Qin · More Details Abstract ...

  11. Bulletin of Materials Science | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Bulletin of Materials Science. G P Nayaka. Articles written in Bulletin of Materials Science. Volume 37 Issue 3 May 2014 pp 705-711. Structural, electrical and electrochemical behaviours of LiNi0.4M0.1Mn1.5O4 ( = Al, Bi) as cathode material for Li-ion batteries · G P Nayaka J Manjanna K C Anjaneya P ...

  12. Bulletin of Materials Science | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Bulletin of Materials Science. S K Singh. Articles written in Bulletin of Materials Science. Volume 25 Issue 6 November 2002 pp 561-563. Synthesis of SiC from rice husk in a plasma reactor · S K Singh B C Mohanty S Basu · More Details Abstract Fulltext PDF. A new route for production of SiC from rice husk ...

  13. Bulletin of Materials Science | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Bulletin of Materials Science. C H Xia. Articles written in Bulletin of Materials Science. Volume 34 Issue 5 August 2011 pp 1033-1037. Synthesis of Mn-doped CeO2 nanorods and their application as humidity sensors · C H Hu C H Xia F Wang M Zhou P F Yin X Y Han · More Details Abstract Fulltext PDF.

  14. r ben hassine - Bulletin of Materials Science | Indian Academy of ...

    Indian Academy of Sciences (India)

    Home; Journals; Bulletin of Materials Science. R BEN HASSINE. Articles written in Bulletin of Materials Science. Volume 40 Issue 1 February 2017 pp 79-85. Effect of Co substitution on the physicochemical properties of La 0.67 Sr 0.22 Ba 0.11 Mn 1 − x Co x O 3 compounds ( 0 ≤ x ≤ 0.3 ) · W CHERIF R BEN HASSINE J A ...

  15. Bulletin of Materials Science | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Bulletin of Materials Science. K C Anjaneya. Articles written in Bulletin of Materials Science. Volume 37 Issue 3 May 2014 pp 705-711. Structural, electrical and electrochemical behaviours of LiNi0.4M0.1Mn1.5O4 ( = Al, Bi) as cathode material for Li-ion batteries · G P Nayaka J Manjanna K C Anjaneya P ...

  16. Extended safety, immunogenicity and efficacy of a blood-stage malaria vaccine in malian children: 24-month follow-up of a randomized, double-blinded phase 2 trial.

    Directory of Open Access Journals (Sweden)

    Matthew B Laurens

    Full Text Available The FMP2.1/AS02A candidate malaria vaccine was tested in a Phase 2 study in Mali. Based on results from the first eight months of follow-up, the vaccine appeared well-tolerated and immunogenic. It had no significant efficacy based on the primary endpoint, clinical malaria, but marginal efficacy against clinical malaria in secondary analyses, and high allele-specific efficacy. Extended follow-up was conducted to evaluate extended safety, immunogenicity and efficacy.A randomized, double-blinded trial of safety, immunogenicity and efficacy of the candidate Plasmodium falciparum apical membrane antigen 1 (AMA1 vaccine FMP2.1/AS02A was conducted in Bandiagara, Mali. Children aged 1-6 years were randomized in a 1∶1 ratio to receive FMP2.1/AS02A or control rabies vaccine on days 0, 30 and 60. Using active and passive surveillance, clinical malaria and adverse events as well as antibodies against P. falciparum AMA1 were monitored for 24 months after the first vaccination, spanning two malaria seasons.400 children were enrolled. Serious adverse events occurred in nine participants in the FMP2.1/AS02A group and three in the control group; none was considered related to study vaccination. After two years, anti-AMA1 immune responses remained significantly higher in the FMP2.1/AS02A group than in the control group. For the entire 24-month follow-up period, vaccine efficacy was 7.6% (p = 0.51 against first clinical malaria episodes and 9.9% (p = 0.19 against all malaria episodes. For the final 16-month follow-up period, vaccine efficacy was 0.9% (p = 0.98 against all malaria episodes. Allele-specific efficacy seen in the first malaria season did not extend into the second season of follow-up.Allele-specific vaccine efficacy was not sustained in the second malaria season, despite continued high levels of anti-AMA1 antibodies. This study presents an opportunity to evaluate correlates of partial protection against clinical malaria that waned during

  17. Bulletin KSNU. Natural science series, no. 1

    International Nuclear Information System (INIS)

    Mansurov, Z.A.

    1997-01-01

    This is the first issue of natural sciences series of Bulletin of Kazak State National University published in English. The objective of the publication is to make scientific ideas and pratical experience of scientists of the University available for the world wide scientific community. This set of articles reflects the curriculum of the University and includes papers on Mathematics, Physics, Chemistry, Biology and Geography. More specifically the papers deal with various aspects of relativity theory, gravitation and quantum mechanics; heat-mass transfer phenomena; physics of plasma; solid state physics and material sciences; theoretical and nuclear physics and physics of cosmic rays; chemistry of polymers; medical materials; oil chemistry and processing; physiology and biochemistry, genetics and biotechnology; assessment of anthroprogenic impact on environment and landscapes; environment friendly industry and agriculture, wise use of natural resources

  18. Bulletin KSNU. Natural science series, no. 1

    Energy Technology Data Exchange (ETDEWEB)

    Mansurov, Z A [ed.

    1998-12-31

    This is the first issue of natural sciences series of Bulletin of Kazak State National University published in English. The objective of the publication is to make scientific ideas and pratical experience of scientists of the University available for the world wide scientific community. This set of articles reflects the curriculum of the University and includes papers on Mathematics, Physics, Chemistry, Biology and Geography. More specifically the papers deal with various aspects of relativity theory, gravitation and quantum mechanics; heat-mass transfer phenomena; physics of plasma; solid state physics and material sciences; theoretical and nuclear physics and physics of cosmic rays; chemistry of polymers; medical materials; oil chemistry and processing; physiology and biochemistry, genetics and biotechnology; assessment of anthroprogenic impact on environment and landscapes; environment friendly industry and agriculture, wise use of natural resources

  19. Safety and immunogenocity of a novel combined Haemophilus influenzae type b-Neisseria meningitidis serogroups A and C-tetanus-toxoid conjugate vaccine in healthy Chinese children aged 6 months to 5 years old.

    Science.gov (United States)

    Hu, Jian-li; Tao, Hong; Li, Jing-xin; Dai, Wei-ming; Song, Bin; Sun, Jin-fang; Liu, Pei; Tang, Jie; Liu, Wen-yu; Wang, Shi-yuan; Zhu, Feng-cai

    2015-01-01

    A novel combined Haemophilus influenzae type b-Neisseria meningitidis serogroups A and C-tetanus-toxoid conjugate vaccine (Hib-MenAC vaccine) has been developed to protect children against diseases caused by Hib, MenA, and MenC. This study investigated the safety and immunogenicity of the Hib-MenAC vaccine administered in 2-dose series to children aged 6-23 months and in a single dose to children aged 2-5 y. A randomized, positive-controlled, non-inferiority clinical trial was conducted for 1200 healthy participants in each age group. Within each age group, participants were randomly allocated to the Hib-MenAC group or the control group at a ratio of 1:1. Adverse reactions were recorded within 28 d after each dose. Blood samples were obtained to assess immunogenicity on day 0 and at 28 d after a complete vaccination course. For the investigational vaccine, the incidence of total adverse reactions in vaccinees aged 6-23 months was 46.8% and that in vaccinees aged 2-5 y was 29.8%. Most adverse reactions were mild or moderate. One non-fatal serious adverse event occurred in the Hib-MenAC group, but was unrelated to vaccination. The seroconversion rate to the 3 components reached 94.0%, and the proportion of vaccinees with rSBA titers ≥ 1:8 and PRP ≥ 0.15 g/mL reached 97.0% in both age groups. The safety and immunogenicity of the Hib-MenAC vaccine were non-inferior when compared to the licensed vaccines. It was concluded that the novel vaccine would be expected to protect children against all of the targeted diseases.

  20. Efficacy and safety of paliperidone palmitate three-monthly formulation in East Asian patients with schizophrenia: subgroup analysis of a global, randomized, double-blind, Phase III, noninferiority study

    Directory of Open Access Journals (Sweden)

    Savitz AJ

    2017-08-01

    Full Text Available Adam J Savitz,1 Haiyan Xu,2 Srihari Gopal,1 Isaac Nuamah,2 Paulien Ravenstijn,3 David Hough,1 Maju Mathews,4 Yu Feng,5 Lu Yu,6 Masayoshi Takahashi,7 Dennis Liu,8 Gang Wang,9 Jin-Sang Yoon,10 Jiahn-Jyh Chen11 1Department of Central Nervous System, 2Department of Clinical Biostatistics, Janssen Research & Development, LLC, Titusville, NJ, USA; 3Department of Clinical Pharmacology, Janssen Research & Development, Beerse, Belgium; 4Global Medical Affairs, Neurosciences, Janssen Research & Development, NY, USA; 5Medical Affairs, Neurosciences, Janssen Pharmaceutical Companies of Johnson and Johnson, Singapore; 6Department of Clinical Development, Janssen Research & Development, Beijing, China; 7Department of Central Nervous System, Janssen Pharmaceutical KK, Tokyo, Japan; 8Playford Community Team, Northern Adelaide Local Health Network, Adelaide, SA, Australia; 9National Clinical Research Center for Mental Disorders, Beijing Anding Hospital, Affiliated Capital University of Medical Science, Beijing, China; 10Department of Psychiatry, Chonnam National University Hospital, Gwangju, South Korea; 11Department of Geriatric Psychiatry, Taoyuan Mental Hospital, Taoyuan, Taiwan Objective: To demonstrate the efficacy and safety of paliperidone palmitate three-monthly (PP3M formulation in an East Asian population with schizophrenia by subgroup analysis of a double-blind (DB, multicenter, noninferiority study. Patients and methods: Of 1,429 patients who entered the open-label (OL phase, 510 were East Asian (China: 296 [58%], Japan: 175 [34%], South Korea: 19 [4%] and Taiwan: 20 [4%]. In the 17-week OL phase, patients received paliperidone palmitate once-monthly (PP1M formulation on day 1 (150 mg eq., day 8 (100 mg eq. and once-monthly thereafter (50–150 mg eq., flexible. Following the OL phase, patients (n=344 East Asian entered DB phase and were randomized (1:1 to PP1M (n=174 or PP3M (n=170. Primary efficacy endpoint was the percentage of patients who

  1. Efficacy and safety of nimesulide long term administration in patients with osteoarthritis: results of 12-months open controlled study DINAMO (long term administration of nimesulide in osteoarthritis multifactor assessment

    Directory of Open Access Journals (Sweden)

    L I Alexeeva

    2009-01-01

    Full Text Available Objective. To compare efficacy and safety of nimesulide and paracetamol in treatment of patients with osteoarthritis (OA during 12 months. Material and methods. 40 women (mean age 66,8±5,1 years with knee osteoarthritis (II-III stage according to Kellgren-Lawrence having intensive pain (>40 mm on VAS were included. Group 1 pts (n=20 received nimesulide 200-100 mg/day. Group 2 pts were treated with paracetamol till 3 g/day. WOMAC was used as efficacy measure. Safety was assessed with endoscopic examination of upper gastrointestinal tract, ECG, blood pressure and ECG Holter monitoring, clinical and biochemical blood parameters. Statistical significance of differences was assessed with Student’s t-test, χ2 and Fisher exact test Results. WOMAC index decreased during treatment from 1182,7±345,9 to 698,4±351,1 for nimesulide and from 1136,4±313,8 to 1031,6±21 for paracetamol (p<0,05. There were 6 cases of gastrointestinal complications and 4 cases of hypertension development or deterioration in each group. Coronary heart disease developed or deteriorated in 4 patients receiving nimesulide but not in control group. Liver function tests did not deteriorated during treatment with nimesulide. Conclusion. Nimesulide was more effective than paracetamol in treatment of OA. But risk of cardiovascular complications development during treatment with NSAIDs requires serious attention. Nimesulide did not induced liver damage during long term treatment.

  2. Immunogenicity and Safety of Yellow Fever Vaccine (Stamaril) When Administered Concomitantly With a Tetravalent Dengue Vaccine Candidate in Healthy Toddlers at 12-13 Months of Age in Colombia and Peru: A Randomized Trial.

    Science.gov (United States)

    López, Pio; Lanata, Claudio F; Zambrano, Betzana; Cortés, Margarita; Andrade, Teresa; Amemiya, Isabel; Terrones, Cynthia; Gil, Ana I; Verastegui, Hector; Marquez, Viviana; Crevat, Denis; Jezorwski, John; Noriega, Fernando

    2016-10-01

    Dengue and yellow fever (YF) viruses are closely related members of the Flaviviridae family. Given the inherent similarities between the YF vaccine and dengue vaccine (CYD-TDV) candidate, it is possible that the latter could interfere with the response to the licensed YF vaccine when coadministered. In this randomized, observer-blind, controlled, phase III trial, conducted in Colombia and Peru, 787 toddlers were administered YF vaccine concomitantly with CYD-TDV (group 1) or placebo (group 2), followed by CYD-TDV after 6 and 12 months. YF and dengue neutralizing antibody titers were determined using a 50% plaque reduction neutralization test. Noninferiority was demonstrated if the lower limit of the 2-sided 95% confidence interval of the difference in seroconversion rates [(YF + CYD-TDV) - YF alone] was greater than -10%. The safety of both vaccines was also assessed. Concomitant administration of YF with either CYD-TDV or placebo yielded YF seroconversion rates of 100.0% and 99.7%, respectively. The difference in YF seroconversion rates between the 2 groups was 0.33% (95% confidence interval:0.98; 1.87), demonstrating that the immune response against YF administered concomitantly with CYD-TDV was noninferior to YF administered with placebo. After 2 injections of CYD-TDV, the percentage of participants with dengue titres ≥10 (1/dil) for the 4 dengue serotypes were 91.2%-100% for group 1 and 97.2%-100% in group 2. There were no safety concerns during the study period. Concomitant administration of YF vaccine with CYD-TDV has no relevant impact on the immunogenicity or safety profile of the YF vaccine.

  3. Improved safety at CERN

    CERN Multimedia

    2006-01-01

    As announced in Weekly Bulletin No. 43/2006, a new approach to the implementation of Safety at CERN has been decided, which required taking some managerial decisions. The guidelines of the new approach are described in the document 'New approach to Safety implementation at CERN', which also summarizes the main managerial decisions I have taken to strengthen compliance with the CERN Safety policy and Rules. To this end I have also reviewed the mandates of the Safety Commission and the Safety Policy Committee (SAPOCO). Some details of the document 'Safety Policy at CERN' (also known as SAPOCO42) have been modified accordingly; its essential principles, unchanged, remain the basis for the safety policy of the Organisation. I would also like to inform you that I have appointed Dr M. Bona as the new Head of the Safety Commission until 31.12.2008, and that I will proceed soon to the appointment of the members of the new Safety Policy Committee. All members of the personnel are deemed to have taken note of the d...

  4. The safety, effectiveness and cost-effectiveness of cytisine in achieving six-month continuous smoking abstinence in tuberculosis patients - protocol for a double-blind, placebo-controlled randomised trial.

    Science.gov (United States)

    Dogar, Omara; Barua, Deepa; Boeckmann, Melanie; Elsey, Helen; Fatima, Razia; Gabe, Rhian; Huque, Rumana; Keding, Ada; Khan, Amina; Kotz, Daniel; Kralikova, Eva; Newell, James N; Nohavova, Iveta; Parrott, Steve; Readshaw, Anne; Renwick, Lottie; Sheikh, Aziz; Siddiqi, Kamran

    2018-04-20

    Tuberculosis (TB) patients who quit smoking have much better disease outcomes than those who continue to smoke. Behavioural support combined with pharmacotherapy is the most effective strategy in helping people to quit, in general populations. However, there is no evidence for the effectiveness of this strategy in TB patients who smoke. We will assess the safety, effectiveness and cost-effectiveness of cytisine - a low-cost plant-derived nicotine substitute - for smoking cessation in TB patients compared with placebo, over and above brief behavioural support. Two-arm, parallel, double-blind, placebo-controlled, multi-centre (30 sites in Bangladesh and Pakistan), individually randomised trial. TB treatment centres integrated into public health care systems in Bangladesh and Pakistan. Newly diagnosed (in the last four weeks) adult pulmonary TB patients who are daily smokers (with or without dual smokeless tobacco use) and are interested in quitting (n= 2,388). The primary outcome measure is biochemically verified continuous abstinence from smoking at six months post-randomization, assessed using Russell Standard criteria. The secondary outcome measures include continuous abstinence at 12 months, lapses and relapses; clinical TB outcomes; nicotine dependency and withdrawal; and adverse events. This is the first smoking cessation trial of cytisine in low- and middle-income countries evaluating both cessation and tuberculosis (TB) outcomes. If found effective, cytisine could become the most affordable cessation intervention to help TB patients who smoke. This article is protected by copyright. All rights reserved.

  5. Immunogenicity and Safety of an Inactivated Quadrivalent Influenza Vaccine in US Children 6-35 Months of Age During 2013-2014: Results From A Phase II Randomized Trial.

    Science.gov (United States)

    Wang, Long; Chandrasekaran, Vijayalakshmi; Domachowske, Joseph B; Li, Ping; Innis, Bruce L; Jain, Varsha K

    2016-06-01

    Viruses from 2 influenza B lineages co-circulate, leading to suboptimal protection with trivalent influenza vaccines (TIV). Quadrivalent influenza vaccines (QIV) containing both lineages offer broader protection. We compared inactivated seasonal QIV versus TIV (15 and 7.5 μg hemagglutinin [HA] for each influenza strain, respectively) in a phase II randomized (1 : 1), observer-blind trial in US children 6-35 months of age (identifier NCT01974895). The primary objective was to evaluate immune responses induced by QIV for the 4 vaccine strains 28 days after completion of vaccination. A secondary objective was to demonstrate superiority of QIV versus TIV for the B/Victoria strain contained in QIV but not TIV. Immunogenicity was evaluated in the per-protocol cohort (N = 280), and safety was evaluated in the intent-to-treat cohort (N = 314). Seroconversion rates (SCRs) for QIV were 80.4% (95% confidence interval [CI], 73.0%-86.6%), 72.0% (95% CI, 63.9%-79.2%), 86.0% (95% CI, 79.2%-91.2%), and 66.4% (95% CI, 58.1%-74.1%) for A/H1N1, A/H3N2, B/Yamagata, and B/Victoria, respectively. Quadrivalent influenza vaccines demonstrated immunogenic superiority over TIV for B/Victoria with a geometric mean titer ratio of 4.73 (95% CI, 3.73%-5.99%) and SCR difference of 54.02% (95% CI, 43.88%-62.87%). Safety was similar between the vaccine groups despite the QIV's higher antigen content. No serious adverse events were reported related to vaccination. Quadrivalent influenza vaccine (15 µg HA/strain) was immunogenic with an acceptable safety profile. The next phase of its development in children 6-35 months of age is a phase III trial in countries where it is not yet licensed. In countries where it is already licensed, a switch from TIV to QIV would provide broader protection in this vulnerable group. © The Author 2015. Published by Oxford University Press on behalf of the Pediatric Infectious Diseases Society.

  6. Immunogenicity and Safety of an Inactivated Quadrivalent Influenza Vaccine in US Children 6–35 Months of Age During 2013–2014: Results From A Phase II Randomized Trial

    Science.gov (United States)

    Wang, Long; Chandrasekaran, Vijayalakshmi; Domachowske, Joseph B.; Li, Ping; Innis, Bruce L.; Jain, Varsha K.

    2016-01-01

    Background Viruses from 2 influenza B lineages co-circulate, leading to suboptimal protection with trivalent influenza vaccines (TIV). Quadrivalent influenza vaccines (QIV) containing both lineages offer broader protection. Methods We compared inactivated seasonal QIV versus TIV (15 and 7.5 μg hemagglutinin [HA] for each influenza strain, respectively) in a phase II randomized (1 : 1), observer-blind trial in US children 6–35 months of age (identifier NCT01974895). The primary objective was to evaluate immune responses induced by QIV for the 4 vaccine strains 28 days after completion of vaccination. A secondary objective was to demonstrate superiority of QIV versus TIV for the B/Victoria strain contained in QIV but not TIV. Immunogenicity was evaluated in the per-protocol cohort (N = 280), and safety was evaluated in the intent-to-treat cohort (N = 314). Results Seroconversion rates (SCRs) for QIV were 80.4% (95% confidence interval [CI], 73.0%–86.6%), 72.0% (95% CI, 63.9%–79.2%), 86.0% (95% CI, 79.2%–91.2%), and 66.4% (95% CI, 58.1%–74.1%) for A/H1N1, A/H3N2, B/Yamagata, and B/Victoria, respectively. Quadrivalent influenza vaccines demonstrated immunogenic superiority over TIV for B/Victoria with a geometric mean titer ratio of 4.73 (95% CI, 3.73%–5.99%) and SCR difference of 54.02% (95% CI, 43.88%–62.87%). Safety was similar between the vaccine groups despite the QIV's higher antigen content. No serious adverse events were reported related to vaccination. Conclusions Quadrivalent influenza vaccine (15 µg HA/strain) was immunogenic with an acceptable safety profile. The next phase of its development in children 6–35 months of age is a phase III trial in countries where it is not yet licensed. In countries where it is already licensed, a switch from TIV to QIV would provide broader protection in this vulnerable group. PMID:26407273

  7. 77 FR 35393 - Federal Management Regulation; FMR Bulletin PBS-2012-03; Redesignations of Federal Buildings

    Science.gov (United States)

    2012-06-13

    ... Management Regulation; FMR Bulletin PBS-2012-03; Redesignations of Federal Buildings AGENCY: Public Buildings... bulletin announces the designation and redesignation of three Federal buildings. Expiration Date: This bulletin announcement expires October 31, 2012. The building designation and redesignations remains in...

  8. 75 FR 44264 - Federal Management Regulation; FMR Bulletin PBS-2010-B4; Redesignation of Federal Building

    Science.gov (United States)

    2010-07-28

    ... Management Regulation; FMR Bulletin PBS-2010-B4; Redesignation of Federal Building AGENCY: Public Buildings... announces the redesignation of a Federal building. DATES: Expiration Date: This bulletin expires December 31, 2010. However, the building redesignation announced by this bulletin will remain in effect until...

  9. Safety and Immunogenicity of the HPV-16/18 AS04-adjuvanted Vaccine in 4-6-year-old Girls: Results to Month 12 From a Randomized Trial.

    Science.gov (United States)

    Lin, Lan; Parra, Mercedes Macias; Sierra, Victor Y; Cespedes, Albino Salas; Granados, Maria Angelica; Luque, Adriana; Damaso, Silvia; Castrejon Alba, Maria Mercedes; Romano-Mazzotti, Luis; Struyf, Frank

    2018-04-01

    The burden of cervical cancer caused by human papillomavirus (HPV) is high in Latin America. The suboptimal HPV vaccination coverage in adolescents could be improved by pediatric immunization. HPV vaccination has not yet been reported in girls HPV-16/18 vaccine in 4-6-year-old girls. Healthy girls (randomized 1:1) received either 2 doses of AS04-HPV-16/18 vaccine (HPV group, N=74) or 1 dose of each measles-mumps-rubella and diphtheria-tetanus-acellular-pertussis vaccines (control group, N=74) 6 months apart. We report the safety and serum anti-HPV-16 and anti-HPV-18 antibodies (measured by enzyme-linked immunosorbent assay) up to 6 months postvaccination, that is, month (M) 12. Injection site pain was the most frequently reported solicited local symptom in HPV vaccinees. The incidence of other solicited and unsolicited symptoms after each vaccination was similar between the HPV and control group. Until M12, 1 girl in the HPV group and 2 in the control group reported serious adverse events; all serious adverse events were assessed as unrelated to study vaccines. No potential immune-mediated diseases were identified. All girls seroconverted for both antigens after 2 doses of AS04-HPV-16/18. In initially seronegative girls, anti-HPV-16 geometric mean concentrations were 20080.0 enzyme-linked immunosorbent assay units (EU)/mL at M7 and 3246.5 EU/mL at M12; anti-HPV-18 geometric mean concentrations were 10621.8 EU/mL at M7 and 1216.6 EU/mL at M12. Two-dose vaccination with AS04-HPV-16/18 was well tolerated and induced adequate antibody responses in 4-6-year-old girls.

  10. NRC Bulletin No. 87-02, Supplement 1: Fastener testing to determine conformance with applicable material specifications

    International Nuclear Information System (INIS)

    Rossi, C.E.

    1992-01-01

    Item 5 of NRC Compliance Bulletin 87-02 requested that all holders of operating licenses or construction permits for nuclear power reactors information regarding the identity of the suppliers and manufacturers of the safety-related and non-safety-related fasteners selected for testing. After further consideration, the NRC has determined that it needs information regarding the identity of all vendors from which safety-related and non-safety-related fasteners have been obtained within the past 10 years, a reasonable period which will not put undue burden on addressees. This information will assist the NRC in determining whether nuclear facility fasteners in use have been supplied in accordance with their intended use. In addition, this information is needed so that the NRC can properly coordinate information with other government agencies concerned with problems identified in the quality of fasteners

  11. Guidelines for determining flood flow frequency—Bulletin 17C

    Science.gov (United States)

    England, John F.; Cohn, Timothy A.; Faber, Beth A.; Stedinger, Jery R.; Thomas, Wilbert O.; Veilleux, Andrea G.; Kiang, Julie E.; Mason, Robert R.

    2018-03-29

    Accurate estimates of flood frequency and magnitude are a key component of any effective nationwide flood risk management and flood damage abatement program. In addition to accuracy, methods for estimating flood risk must be uniformly and consistently applied because management of the Nation’s water and related land resources is a collaborative effort involving multiple actors including most levels of government and the private sector.Flood frequency guidelines have been published in the United States since 1967, and have undergone periodic revisions. In 1967, the U.S. Water Resources Council presented a coherent approach to flood frequency with Bulletin 15, “A Uniform Technique for Determining Flood Flow Frequencies.” The method it recommended involved fitting the log-Pearson Type III distribution to annual peak flow data by the method of moments.The first extension and update of Bulletin 15 was published in 1976 as Bulletin 17, “Guidelines for Determining Flood Flow Frequency” (Guidelines). It extended the Bulletin 15 procedures by introducing methods for dealing with outliers, historical flood information, and regional skew. Bulletin 17A was published the following year to clarify the computation of weighted skew. The next revision of the Bulletin, the Bulletin 17B, provided a host of improvements and new techniques designed to address situations that often arise in practice, including better methods for estimating and using regional skew, weighting station and regional skew, detection of outliers, and use of the conditional probability adjustment.The current version of these Guidelines are presented in this document, denoted Bulletin 17C. It incorporates changes motivated by four of the items listed as “Future Work” in Bulletin 17B and 30 years of post-17B research on flood processes and statistical methods. The updates include: adoption of a generalized representation of flood data that allows for interval and censored data types; a new method

  12. Clinical efficacy and safety of a light mask for prevention of dark adaptation in treating and preventing progression of early diabetic macular oedema at 24 months (CLEOPATRA): a multicentre, phase 3, randomised controlled trial.

    Science.gov (United States)

    Sivaprasad, Sobha; Vasconcelos, Joana C; Prevost, A Toby; Holmes, Helen; Hykin, Philip; George, Sheena; Murphy, Caroline; Kelly, Joanna; Arden, Geoffrey B

    2018-05-01

    We aimed to assess 24-month outcomes of wearing an organic light-emitting sleep mask as an intervention to treat and prevent progression of non-central diabetic macular oedema. CLEOPATRA was a phase 3, single-blind, parallel-group, randomised controlled trial undertaken at 15 ophthalmic centres in the UK. Adults with non-centre-involving diabetic macular oedema were randomly assigned (1:1) to wearing either a light mask during sleep (Noctura 400 Sleep Mask, PolyPhotonix Medical, Sedgefield, UK) or a sham (non-light) mask, for 24 months. Randomisation was by minimisation generated by a central web-based computer system. Outcome assessors were masked technicians and optometrists. The primary outcome was the change in maximum retinal thickness on optical coherence tomography (OCT) at 24 months, analysed using a linear mixed-effects model incorporating 4-monthly measurements and baseline adjustment. Analysis was done using the intention-to-treat principle in all randomised patients with OCT data. Safety was assessed in all patients. This trial is registered with Controlled-Trials.com, number ISRCTN85596558. Between April 10, 2014, and June 15, 2015, 308 patients were randomly assigned to wearing the light mask (n=155) or a sham mask (n=153). 277 patients (144 assigned the light mask and 133 the sham mask) contributed to the mixed-effects model over time, including 246 patients with OCT data at 24 months. The change in maximum retinal thickness at 24 months did not differ between treatment groups (mean change -9·2 μm [SE 2·5] for the light mask vs -12·9 μm [SE 2·9] for the sham mask; adjusted mean difference -0·65 μm, 95% CI -6·90 to 5·59; p=0·84). Median compliance with wearing the light mask at 24 months was 19·5% (IQR 1·9-51·6). No serious adverse events were related to either mask. The most frequent adverse events related to the assigned treatment were discomfort on the eyes (14 with the light mask vs seven with the sham mask), painful, sticky, or

  13. Comparative Effectiveness of a Technology-Facilitated Depression Care Management Model in Safety-Net Primary Care Patients With Type 2 Diabetes: 6-Month Outcomes of a Large Clinical Trial.

    Science.gov (United States)

    Wu, Shinyi; Ell, Kathleen; Jin, Haomiao; Vidyanti, Irene; Chou, Chih-Ping; Lee, Pey-Jiuan; Gross-Schulman, Sandra; Sklaroff, Laura Myerchin; Belson, David; Nezu, Arthur M; Hay, Joel; Wang, Chien-Ju; Scheib, Geoffrey; Di Capua, Paul; Hawkins, Caitlin; Liu, Pai; Ramirez, Magaly; Wu, Brian W; Richman, Mark; Myers, Caitlin; Agustines, Davin; Dasher, Robert; Kopelowicz, Alex; Allevato, Joseph; Roybal, Mike; Ipp, Eli; Haider, Uzma; Graham, Sharon; Mahabadi, Vahid; Guterman, Jeffrey

    2018-04-23

    Comorbid depression is a significant challenge for safety-net primary care systems. Team-based collaborative depression care is effective, but complex system factors in safety-net organizations impede adoption and result in persistent disparities in outcomes. Diabetes-Depression Care-management Adoption Trial (DCAT) evaluated whether depression care could be significantly improved by harnessing information and communication technologies to automate routine screening and monitoring of patient symptoms and treatment adherence and allow timely communication with providers. The aim of this study was to compare 6-month outcomes of a technology-facilitated care model with a usual care model and a supported care model that involved team-based collaborative depression care for safety-net primary care adult patients with type 2 diabetes. DCAT is a translational study in collaboration with Los Angeles County Department of Health Services, the second largest safety-net care system in the United States. A comparative effectiveness study with quasi-experimental design was conducted in three groups of adult patients with type 2 diabetes to compare three delivery models: usual care, supported care, and technology-facilitated care. Six-month outcomes included depression and diabetes care measures and patient-reported outcomes. Comparative treatment effects were estimated by linear or logistic regression models that used generalized propensity scores to adjust for sampling bias inherent in the nonrandomized design. DCAT enrolled 1406 patients (484 in usual care, 480 in supported care, and 442 in technology-facilitated care), most of whom were Hispanic or Latino and female. Compared with usual care, both the supported care and technology-facilitated care groups were associated with significant reduction in depressive symptoms measured by scores on the 9-item Patient Health Questionnaire (least squares estimate, LSE: usual care=6.35, supported care=5.05, technology-facilitated care=5

  14. Comparison of the safety and immunogenicity of live attenuated and inactivated hepatitis A vaccine in healthy Chinese children aged 18 months to 16 years: results from a randomized, parallel controlled, phase IV study.

    Science.gov (United States)

    Ma, F; Yang, J; Kang, G; Sun, Q; Lu, P; Zhao, Y; Wang, Z; Luo, J; Wang, Z

    2016-09-01

    For large-scale immunization of children with hepatitis A (HA) vaccines in China, accurately designed studies comparing the safety and immunogenicity of the live attenuated HA vaccine (HA-L) and inactivated HA vaccine (HA-I) are necessary. A randomized, parallel controlled, phase IV clinical trial was conducted with 6000 healthy children aged 18 months to 16 years. HA-L or HA-I was administered at a ratio of 1: 1 to randomized selected participants. The safety and immunogenicity were evaluated. Both HA-L and HA-I were well tolerated by all participants. The immunogenicity results showed that the seroconversion rates (HA-L versus HA-I: 98.0% versus 100%, respectively, p >0.05), and geometric mean concentrations in participants negative for antibodies against HA virus IgG (anti-HAV IgG) before vaccination did not differ significantly between the two types of vaccines (HA-L versus HA-I first dose: 898.9 versus 886.2 mIU/mL, respectively, p >0.05). After administration of the booster dose of HA-I, the geometric mean concentrations of anti-HAV IgG (HA-I booster dose: 2591.2 mIU/mL) was higher than that after the first dose (p children. The effects of long-term immunogenicity after natural exposure to wild-type HA virus and the possibility of mutational shifts of the live vaccine virus in the field need to be studied in more detail. Copyright © 2016. Published by Elsevier Ltd.

  15. Safety and immunogenicity of live-attenuated Japanese encephalitis SA 14-14-2 vaccine co-administered with measles vaccine in 9-month-old infants in Sri Lanka.

    Science.gov (United States)

    Wijesinghe, Pushpa Ranjan; Abeysinghe, M R Nihal; Yoksan, Sutee; Yao, Yafu; Zhou, Benli; Zhang, Lei; Yaich, Mansour; Neuzil, Kathleen M; Victor, John C

    2014-08-20

    To facilitate introduction of live attenuated SA 14-14-2 Japanese encephalitis vaccine (LJEV) into the National Immunization Programme of Sri Lanka, we evaluated the safety and immunogenicity of co-administration of LJEV and measles vaccine at 9 months of age. Serum immune responses were evaluated post-vaccination on days 28, 180, and 365 using JE neutralization test and anti-measles IgG ELISA. 278 infants received one dose of LJEV and measles vaccine. Of these, 257 were eligible for the per-protocol analysis. On Day 0, 14 infants (5.5%) were seropositive for JE, but none were seropositive for measles. At Day 28, seropositivity rates were 90.7% (95% CI, 86.4-93.9%) for JE and 84.8% (95% CI, 79.8-89.0%) for measles. The geometric mean titer for JE neutralizing antibodies was 111 (95% CI, 90-135), and the geometric mean concentration (GMC) for anti-measles IgG was 375 mI U/mL (95% CI, 351-400 mI U/mL). Over the next year, JE neutralizing antibody responses declined only slightly, with seropositivity at 87.4% (95% CI, 82.6-91.2%) at Day 365. In contrast, measles antibody levels continued to increase over time. Seropositivity for anti-measles IgG reached 97.2% (95% CI, 94.4-98.9%) at Day 365, and the GMC rose to 1202 mI U/mL (95% CI, 1077-1341 mI U/mL). Co-administration of LJEV and measles vaccine was also safe. Most adverse reactions were mild, and no serious adverse events were related to study vaccinations. The safety and immunogenicity of LJEV co-administered with measles vaccine in Sri Lankan infants is similar to that seen in other populations, and our results support use of LJEV at 9 months of age. Live SA 14-14-2 vaccine is now prequalified by the WHO for use in infants in Asia, and other countries may wish to introduce LJEV to combat this devastating disease. Copyright © 2014 The Authors. Published by Elsevier Ltd.. All rights reserved.

  16. Public safety around dams guidelines

    Energy Technology Data Exchange (ETDEWEB)

    Bennett, T [Canadian Dam Association, Edmonton, AB (Canada)

    2010-07-01

    This presentation discussed Canadian and international initiatives for improving dam safety and described some of the drivers for the development of new Canadian Dam Association (CDA) public safety guidelines for dams. The CDA guidelines were divided into the following 3 principal sections: (1) managed system elements, (2) risk assessment and management, and (3) technical bulletins. Public and media responses to the drownings have called for improved safety guidelines. While the public remains unaware of the hazards of dams, public interaction with dams is increasing as a result of interest in extreme sports and perceived rights of access. Guidelines are needed for dam owners in order to provide due diligence. Various organizations in Canada are preparing technical and public safety dam guidelines. CDA guidelines have also been prepared for signage, booms and buoys, and audible and visual alerts bulletins. Working groups are also discussing recommended practices for spill procedures, spillways and the role of professional engineers in ensuring public safety. Methods of assessing risk were also reviewed. Managed system elements for risk assessment and public interactions were also discussed, and stepped control measures were presented. tabs., figs.

  17. 75 FR 45696 - Pipeline Safety: Personal Electronic Device Related Distractions

    Science.gov (United States)

    2010-08-03

    ... DEPARTMENT OF TRANSPORTATION Pipeline and Hazardous Materials Safety Administration [Docket No... and operators of natural gas and hazardous liquid pipeline facilities are required to have and follow.... Advisory Bulletin (ADB-10-06) To: Owners and Operators of Hazardous Liquid and Natural Gas Pipeline Systems...

  18. WEEKLY BULLETIN : WE ARE INTERESTED IN YOUR OPINION !

    CERN Multimedia

    2002-01-01

    The Weekly Bulletin publication team has prepared a questionnaire that finally allows you to say all you think, good or bad, about CERN's in-house journal. The aim of this survey is to improve the Bulletin and make it more readable and more practical. In short, we want it to be more useful to you! We will be publishing the results of this survey in a few weeks' time. Between now and then we invite you to fill out the web form, or the form just before the last page of this issue. Just 5 minutes of your time!

  19. Publication of a double Weekly Bulletin over Easter

    CERN Multimedia

    2003-01-01

    During the Easter period, the weeks of 21 and 28 April, there will be only one issue of the Weekly Bulletin (n°17-18/2003). Items for publication in this double issue should reach the Publication section or the Staff Association, as appropriate, before midday on Tuesday 15 April. There will therefore be no Bulletin distribution on Friday 25 April. Announcements for publication in the next issue (n°19/2003) should be sent on Tuesday 29 April by noon. Publications Section/ETT Tel. 79971

  20. Bureau of hydrocarbons exploration-production (BEPH) - Monthly information bulletin. June 2006

    International Nuclear Information System (INIS)

    2006-06-01

    This newsletter takes stock of the recent highlights in the domain of hydrocarbons exploration and production in the French territory: mining domain (demands, allocations and extension of research permits and concessions; list of demands under instruction), drilling activity (new drillings, advance of existing exploratory and extension-development drillings); production activity (interventions on wells, crude oil, crude gas, commercialized gas, natural gas-derived hydrocarbons, related products, production shares by company in the Paris and Aquitain basins). (J.S.)

  1. Bureau of hydrocarbons exploration-production (BEPH) - Monthly information bulletin. February 2006

    International Nuclear Information System (INIS)

    2006-02-01

    This newsletter takes stock of the recent highlights in the domain of hydrocarbons exploration and production in the French territory: mining domain (demands and allocations of research permits), drilling activity (new drillings, advance of existing exploratory and extension-development drillings); production activity (interventions on wells, crude oil, crude gas, commercialized gas, natural gas-derived hydrocarbons, related products, production shares by company in the Paris and Aquitain basins). (J.S.)

  2. Bureau of hydrocarbons exploration-production (BEPH) - Monthly information bulletin. September 2006

    International Nuclear Information System (INIS)

    2006-09-01

    This newsletter takes stock of the recent highlights in the domain of hydrocarbons exploration and production in the French territory: mining domain (demands of research permits; list of demands under instruction), drilling activity (new drillings, advance of existing exploratory and extension-development drillings); production activity (interventions on wells, crude oil, crude gas, commercialized gas, natural gas-derived hydrocarbons, related products, production shares by company in the Paris and Aquitain basins). (J.S.)

  3. Bureau of hydrocarbons exploration-production (BEPH) - Monthly information bulletin. May 2006

    International Nuclear Information System (INIS)

    2006-05-01

    This newsletter takes stock of the recent highlights in the domain of hydrocarbons exploration and production in the French territory: mining domain (demands of research permits; list of demands under instruction), seismic survey activity, production activity (interventions on wells, crude oil, crude gas, commercialized gas, natural gas-derived hydrocarbons, related products, production shares by company in the Paris and Aquitain basins). (J.S.)

  4. Bureau of hydrocarbons exploration-production (BEPH) - Monthly information bulletin. April 2006

    International Nuclear Information System (INIS)

    2006-04-01

    This newsletter takes stock of the recent highlights in the domain of hydrocarbons exploration and production in the French territory: mining domain (demands of research permit, allocations of concession), geophysical survey activity, drilling activity (new drillings, advance of existing exploratory and extension-development drillings); production activity (interventions on wells, crude oil, crude gas, commercialized gas, natural gas-derived hydrocarbons, related products, production shares by company in the Paris and Aquitain basins). (J.S.)

  5. Bureau of hydrocarbons exploration-production (BEPH) - Monthly information bulletin. December 2006

    International Nuclear Information System (INIS)

    2006-12-01

    This newsletter takes stock of the recent highlights in the domain of hydrocarbons exploration and production in the French territory: mining domain (demands and allocations of research permits and concessions; list of demands under instruction), drilling activity (new drillings, advance of existing exploratory and extension-development drillings); production activity (interventions on wells, crude oil, crude gas, commercialized gas, natural gas-derived hydrocarbons, related products, production shares by company in the Paris and Aquitain basins); underground storage facilities (allocation and extension of concessions). (J.S.)

  6. Nuclear law bulletin supplement to no. 72

    CERN Document Server

    2003-01-01

    When the Joint Convention on the Safety of Spent Fuel Management and on the Safety ofRadioactive Waste Management1 came into force in June 2002, following by almost five years theentry into force of the Convention on Nuclear Safety (CNS),2 the major elements3 of the InternationalAtomic Energy Agency's long-planned international legal regime on nuclear safety4 appeared to befinally in place. This fact might have been expected to be a cause for general satisfaction, if not

  7. A 6-month study comparing efficacy, safety, and tolerability of the preservative-free fixed combination of tafluprost 0.0015% and timolol 0.5% versus each of its individual preservative-free components.

    Science.gov (United States)

    Pfeiffer, Norbert; Traverso, Carlo E; Lorenz, Katrin; Saarela, Ville; Liinamaa, Johanna; Uusitalo, Hannu; Astakhov, Yury; Boiko, Ernest; Ropo, Auli

    2014-12-01

    The efficacy, safety and tolerability of the preservative-free (PF) fixed combination (FC) of tafluprost 0.0015% and timolol 0.5% (once daily) were compared to those of the individual components (PF tafluprost 0.0015% once daily and PF timolol 0.5% twice daily) in patients with open-angle glaucoma or ocular hypertension inadequately controlled on prior timolol or prostaglandin monotherapy for 6 months. A stratified, double-masked, randomized, multicenter phase III study was conducted. A total of 189 prior timolol users were randomized within the timolol stratum (TS) to receive either FC (n = 95) or timolol 0.5% (TIM; n = 94). Furthermore, a total of 375 prior prostaglandin analog (PGA) users were randomized within the prostaglandin stratum (PS) to receive either FC (n = 188) or tafluprost 0.0015% (TAF; n = 187). To be eligible for participation in the study, the patients were required to have an intraocular pressure (IOP) of ≥22 mmHg when on timolol (TIM) or of ≥20 mmHg when on PGA in either treated eye at the screening and end-of-run-in visits. In addition to these, the study included visits at baseline, 2 and 6 weeks, 3 and 6 months and at a post-study visit. IOP was measured at 8 a.m., 10 a.m., 4 p.m., and 8 p.m. In the TS, a significant reduction from baseline IOP was seen with FC and TIM throughout the study. Average diurnal IOP change from baseline at month 3 was -8.55 mmHg (32%) for FC and -7.35 mmHg (28%) for TIM. The model-based treatment difference (FC-TIM) was -0.885 mmHg [95% confidence interval (CI) -1.745 to -0.024; p = 0.044] demonstrating the superiority of FC over TIM. In the PS, a significant reduction in IOP was seen with both FC and TAF throughout the study. The average diurnal IOP change from baseline at month 3 was -8.61 mmHg (33%) for FC and -7.23 mmHg (28%) for TAF. The model-based treatment difference (FC-TAF) was -1.516 mmHg (95% CI -2.044 to -0.988; p preservative-free fixed combination of tafluprost and

  8. Bulletin of Materials Science | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Bulletin of Materials Science; Volume 32; Issue 5 ... of CdTe nanoparticles before and after transfer from liquid phase to polystyrene ... Catalytic synthesis of ZnO nanorods on patterned silicon wafer—An optimum material for gas .... Hot-rolled, warm-rolled and heat treated alloys were examined using optical ...

  9. Bulletin of Materials Science | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Bulletin of Materials Science; Volume 31; Issue 3. Formation of InN nanoparticle and nanorod structures by nitrogen plasma annealing method ... Department of Physics, Indian Institute of Technology Delhi, New Delhi 110 016, India; Material Science Division, Indira Gandhi Centre for Atomic Research, ...

  10. Bulletin of Materials Science | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Bulletin of Materials Science; Volume 36; Issue 1. Characterization and in vitro and in vivo evaluation of cross-linked chitosan films as implant for controlled release of citalopram. Patit P Kundu Santosh Kumar Jindal Manish Goswami. Volume 36 Issue 1 February 2013 pp 175-182 ...

  11. Electric Motors: Technical Terminology Bulletin. Terminotech, Vol. 1, No. 2.

    Science.gov (United States)

    General Electric Co. of Canada, Ltd., Montreal, Quebec.

    This issue of a bulletin of technological terminology is devoted to electric motors. A brief narrative on the subject is included in both French and English. An English-French dictionary of terms comprises the bulk of the document. Explanatory illustrations are appended (JB).

  12. Bulletin of Materials Science | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Bulletin of Materials Science; Volume 30; Issue 5. Influence of additives on electrodeposition of bright Zn–Ni alloy on mild steel from acid sulphate bath. S Shivakumara U Manohar Y Arthoba Naik T V Venkatesha. Alloys and Steels Volume 30 Issue 5 October 2007 pp 455-462 ...

  13. Bulletin of Materials Science | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Bulletin of Materials Science; Volume 39; Issue 3. Structural investigation of V 2 O 5 –P 2 O 5 –K 2 O glass system with antibacterial potential. N S VEDEANU I B COZAR R STANESCU R STEFAN D VODNAR O COZAR. Volume 39 Issue 3 June 2016 pp 697-702 ...

  14. Bulletin of Materials Science | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Bulletin of Materials Science; Volume 40; Issue 5. Electro-optical properties, decomposition pathways and the hydrostatic pressure-dependent behaviours of a double-cation hydrogen storage material of Al 3 Li 4 (BH 4 ) 13. MEHMET SIMSEK. Volume 40 Issue 5 September 2017 pp 907-915 ...

  15. Bulletin of Materials Science | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Articles written in Bulletin of Materials Science. Volume 27 Issue 5 October 2004 pp 417-420 Nuclear Related Materials. Irradiation of large area Mylar membrane and characterization of ... Effect of ion beam irradiation on metal particle doped polymer composites · N L Singh Sejal Shah Anjum Qureshi A Tripathi F Singh D K ...

  16. Bulletin of Materials Science | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Articles written in Bulletin of Materials Science. Volume 29 Issue 2 April 2006 pp 101-105 Polymers. Proton microbeam irradiation effects on PtBA polymer ... optical and secondary electron microscopic experimental methods. Volume 34 Issue 4 July 2011 pp 595-599. Thermal stability of gold-PS nanocomposites thin films.

  17. Bulletin of Materials Science | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Bulletin of Materials Science; Volume 31; Issue 1. Pressure induced graft-co-polymerization of acrylonitrile onto Saccharum cilliare fibre and ... Author Affiliations. A S Singha1 Anjali Shama1 Vijay Kumar Thakur1. Material Science Laboratory, National Institute of Technology, Hamirpur 177 005, India ...

  18. Bulletin of Materials Science | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Bulletin of Materials Science; Volume 27; Issue 5 ... The electrical performances of thin film material can be improved largely by dopants. ... Department of Materials Science and Engineering, Jinan University, Jinan 250022, PR China; The State Key Laboratory of Material Composite and Advanced ...

  19. Bulletin of Materials Science | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Bulletin of Materials Science; Volume 39; Issue 2. Efficiency of surface modified Ti coated with copper nanoparticles to control marine bacterial adhesion under laboratory simulated conditions. CHOKKALINGAM PRIYA GANESSIN ARAVIND WILSON RICHARD THILAGARAJ. Volume 39 Issue 2 April 2016 ...

  20. Bulletin of Materials Science | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Bulletin of Materials Science; Volume 27; Issue 3. Comparative investigation on the effect of alkaline earth oxides on the intensity of absorption bands due to Cu2+, Mn3+ and Cr3+ ions in ternary silicate glasses. S P Singh Aman Anal Tarafder. Glasses Volume 27 Issue 3 June 2004 pp 281-287 ...

  1. EINGEERING BULLETINS: AIDS TO THE DEVELOPMENT OF REMEDIAL ALTERNATIVES

    Science.gov (United States)

    An overview of activities of the Risk Reduction Engineering Laboratory in response to the Environmental Protection Agency`s Treatability Initiative are described and a summary of the information in the first ten Engineering Bulletins, which are a component of the initiative, is p...

  2. Guidelines for CPR Training in Louisiana Schools. Bulletin No. 1638.

    Science.gov (United States)

    Louisiana State Dept. of Education, Baton Rouge.

    Completion of a course in cardiopulmonary resuscitation (CPR) is required for graduation from high school in Louisiana. This bulletin presents the guidelines for a course in CPR and was prepared with the cooperation of the American Red Cross (ARC) and the American Heart Association (AHA). At the conclusion of the course, students will be prepared…

  3. Education in New Zealand. Bulletin, 1964, No. 34. OE-14105

    Science.gov (United States)

    Berrien, Marcia T.

    1964-01-01

    This bulletin presents a study of the development of education in New Zealand. Chapter I, Historical Development of Education, covers the growth of education since 1877. Chapter II, Educational Administration and Finance provides details on the Act of 1877; the organization, functions and responsibilities of the Department of Education; and the…

  4. Bulletin of Materials Science | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Bulletin of Materials Science; Volume 33; Issue 4 ... Permittivity; polarization effects; strontium tartrate; thermal properties; dielectric properties. ... It is explained that crystallographic change due to polymorphic phase transition may be occurring in the material, besides the change due to loss of water ...

  5. Bulletin of Materials Science | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    K Ramachandran. Articles written in Bulletin of Materials Science. Volume 25 Issue 4 August 2002 pp ... Volume 27 Issue 5 October 2004 pp 403-407 Phase Transitions. Phase transition in L-alaninium oxalate by ... Thermal and structural properties of spray pyrolysed CdS thin film · P Raji C Sanjeeviraja K Ramachandran.

  6. Bulletin of Materials Science | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Bulletin of Materials Science; Volume 35; Issue 5. Effect of rolling deformation and solution treatment on ... By the solution treatment, the elongated and broken crystalline grains recrystallize which leads to the formation of finer grains (<10 m) of austenite. X-ray diffraction analysis has corroborated well with ...

  7. Bulletin of Materials Science | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Bulletin of Materials Science; Volume 23; Issue 3. Optimization of growth of InGaAs/InP quantum wells using photoluminescence and secondary ion mass spectrometry. S Bhunia P Banerji T K Chaudhuri A R Haldar D N Bose Y Aparna M B Chettri B R Chakraborty. Semiconducting Materials Volume 23 ...

  8. Bulletin of Materials Science | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    ... Workshops · Refresher Courses · Symposia · Live Streaming. Home; Journals; Bulletin of Materials Science; Volume 36; Issue 4. Magnetic resonance in superparamagnetic zinc ferrite. Jitendra Pal Singh Gagan Dixit R C Srivastava Hemant Kumar H M Agrawal Prem Chand. Volume 36 Issue 4 August 2013 pp 751-754 ...

  9. Bulletin of Materials Science | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    ... Refresher Courses · Symposia · Live Streaming. Home; Journals; Bulletin of Materials Science; Volume 36; Issue 4. Enhanced high temperature performance of LiMn2O4 coated with Li3BO3 solid electrolyte. Liu Jinlian Wu Xianming Chen Shang Liu Jianben He Zeqiang. Volume 36 Issue 4 August 2013 pp 687-691 ...

  10. Bulletin of Materials Science | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Bulletin of Materials Science; Volume 33; Issue 1. Dispersion and reinforcing mechanism of carbon nanotubes in epoxy nanocomposites. Smrutisikha Bal ... Author Affiliations. Smrutisikha Bal1. Department of Metallurgical and Materials Engineering, National Institute of Technology, Rourkela 769 008, India ...

  11. Bulletin of Materials Science | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Bulletin of Materials Science; Volume 39; Issue 1. Preparation of new thermoluminescent material ( 100 − x )B 2 O 3 –xLi 2 O: Cu 2 + for sensing and detection of radiation. Zeid A Alothman Tansir Ahamad Mu Naushad Saad M Alshehri. Volume 39 Issue 1 February 2016 pp 331-336 ...

  12. Bulletin of Materials Science | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Bulletin of Materials Science; Volume 39; Issue 5. Effect of height to diameter ( h / d ) ratio on the deformation behaviour of Fe–Al 2 O 3 metal matrix nanocomposites. PALLAV GUPTA DEVENDRA KUMAR A K JHA OM PARKASH. Volume 39 Issue 5 September 2016 pp 1245-1258 ...

  13. Bulletin of Materials Science | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    ... Public Lectures · Lecture Workshops · Refresher Courses · Symposia · Live Streaming. Home; Journals; Bulletin of Materials Science; Volume 39; Issue 5. Synthesis and luminescence properties of Tb 3 + − d o p e d L i M g P O _4$ phosphor. C B PALAN N S BAJAJ A SONI S K OMANWAR. Volume 39 Issue 5 September ...

  14. Bulletin of Materials Science | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Bulletin of Materials Science; Volume 40; Issue 5. Optical spectroscopy of rare earth-doped oxyfluoro-tellurite glasses to probe local environment. GAJANAN V HONNAVAR K P RAMESH ... Keywords. Tellurite glasses; Raman spectroscopy; photoluminscence; Stark level splitting; UV visible spectroscopy.

  15. Bulletin of Materials Science | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Bulletin of Materials Science; Volume 35; Issue 5. Effect of nitrogen flow ratio on structure and properties of zirconium nitride films on Si(100) prepared by ion beam sputtering. Shahab Norouzian Majid Mojtahedzadeh Larijani Reza Afzalzadeh. Volume 35 Issue 5 October 2012 pp 885-887 ...

  16. Bulletin of Materials Science | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Bulletin of Materials Science; Volume 36; Issue 5. Thickness effect on properties of titanium film deposited by d.c. magnetron sputtering and electron beam evaporation techniques. Nishat Arshi Junqing Lu Chan Gyu Lee Jae Hong Yoon Bon Heun Koo Faheem Ahmed. Volume 36 Issue 5 October 2013 pp ...

  17. Bulletin of Materials Science | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Bulletin of Materials Science; Volume 31; Issue 2. Studies on in vitro release of CPM from semi-interpenetrating polymer network (IPN) composed of chitosan and glutamic acid. K Kumari P P Kundu. Polymers Volume 31 Issue 2 April 2008 pp 159-167 ...

  18. Suicide Bulletin Board Systems Comparison between Japan and Germany

    Science.gov (United States)

    Sueki, Hajime; Eichenberg, Christiane

    2012-01-01

    An online questionnaire (n = 301) was conducted to analyze the cross-cultural influence of the use of suicide bulletin board systems. Factor analysis demonstrated that participants had two types of motives: the constructive motive of mutual help and the destructive motive of suicide preparation. The results showed that suicidal thoughts did not…

  19. Bulletin of Materials Science | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Articles written in Bulletin of Materials Science. Volume 26 Issue 2 February 2003 pp 247-253 Electrical Properties. Impedance spectroscopy ... the a.c. conductivity data. Volume 26 Issue 7 December 2003 pp 745-747 Electrical Properties. Dielectric properties of piezoelectric 3–0 composites of lithium ferrite/barium titanate.

  20. Bulletin of Materials Science | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Articles written in Bulletin of Materials Science. Volume 30 Issue 4 August 2007 pp 301-308 Biomaterials. Adhesive B-doped DLC films on ... Volume 30 Issue 4 August 2007 pp 407-413 Alloys and Steels. Structural phase transitions and piezoelectric anomalies in ordered Sc0.5Ga0.5N alloys · A M Alsaad A A Ahmad.

  1. Bulletin of Materials Science | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Bulletin of Materials Science; Volume 35; Issue 2 ... Surface texture modification of spin-coated SiO2 xerogel thin films by TMCS silylation .... Influence of pH and bath composition on properties of Ni–Fe alloy films ... Diffuse phase transition, piezoelectric and optical study of Bi0.5Na0.5TiO3 ceramic.

  2. Bulletin of Materials Science | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Bulletin of Materials Science; Volume 38; Issue 7. Glassy carbon electrodes modified with gelatin functionalized reduced graphene oxide nanosheet for determination of gallic acid. Fereshteh Chekin Samira Bagheri Sharifah Bee Abd Hamid. Volume 38 Issue 7 December 2015 pp 1711-1716 ...

  3. OCRWM Bulletin: Westinghouse begins designing multi-purpose canister

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1995-09-01

    This publication consists of two parts: OCRWM (Office of Civilian Radioactive Waste Management) Bulletin; and Of Mountains & Science which has articles on the Yucca Mountain project. The OCRWM provides information about OCRWM activities and in this issue has articles on multi-purpose canister design, and transportation cask trailer.

  4. Bulletin of Materials Science | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Bulletin of Materials Science; Volume 30; Issue 2 ... TSDC; PS; naphthalene; thermo-electrets; glass transition temperature (g). Abstract. The electrical conductivity of naphthalene doped polystyrene (PS) films (≈ 61.58 m thick) was studied as a function of dopant concentration and temperature.

  5. Bulletin of Materials Science | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    V Renteria. Articles written in Bulletin of Materials Science. Volume 38 Issue 1 February 2015 pp 29-40. Yttrium deposition on mesoporous TiO2: textural design and UV decolourization of organic dyes · M L Ojeda C Velasquez V Renteria A Campero M A García-Sánchez F Rojas · More Details Abstract Fulltext PDF.

  6. Bulletin of Materials Science | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Bulletin of Materials Science; Volume 34; Issue 4. Preparation of titanium diboride powders from titanium alkoxide ... The influence of TTIP concentration, reaction temperature and molar ratio of precursors on the synthesis of titanium diboride was investigated. Three different concentrations of TTIP solution, ...

  7. Bulletin of Materials Science | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Bulletin of Materials Science; Volume 38; Issue 4 ... The energy diagram shows the feasibility of La2CuO4 for the H2 evolution under visible light. ... Laboratory of Storage and Valorization of Renewable Energies, Faculty of ...

  8. Bulletin of Materials Science | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Bulletin of Materials Science; Volume 37; Issue 3. Microstructural and optical properties of transparent conductive ZnO : Al : Mo films deposited by template-assisted sol–gel method. H-Y He J-F Huang Z He J Lu Q Shen. Volume 37 Issue 3 May 2014 pp 519-525 ...

  9. 76 FR 17191 - Staff Accounting Bulletin No. 114

    Science.gov (United States)

    2011-03-28

    ... statements and those prescribing disclosures that explain, modify or supplement the accounting measurements... which material revenues or expenses are recorded; and Significant accounting policies and measurement... Staff Accounting Bulletin No. 114; Rule #0;#0;Federal Register / Vol. 76 , No. 59 / Monday, March 28...

  10. OCRWM Bulletin: Westinghouse begins designing multi-purpose canister

    International Nuclear Information System (INIS)

    1995-01-01

    This publication consists of two parts: OCRWM (Office of Civilian Radioactive Waste Management) Bulletin; and Of Mountains ampersand Science which has articles on the Yucca Mountain project. The OCRWM provides information about OCRWM activities and in this issue has articles on multi-purpose canister design, and transportation cask trailer

  11. Bulletin of Materials Science | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Bulletin of Materials Science; Volume 33; Issue 2. Evaluation of borax solid wastes in production of frits suitable for fast single-fired wall tile opaque glass–ceramic glazes. K Pekkan B Karasu. Ceramics and Glasses Volume 33 Issue 2 April 2010 pp 135-144 ...

  12. Bulletin of Materials Science | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Bulletin of Materials Science; Volume 31; Issue 4 .... Synthesis and structural studies of Na2O–ZnO–ZnF2–B2O3 oxyfluoride glasses ... processing: A potential technique for preparing NiO–YSZ composite and Ni–YSZ cermet.

  13. School Insurance: Managing the Local Program. Bulletin, 1959, No. 23

    Science.gov (United States)

    Finchum, R. N.; Viles, N. E.

    1959-01-01

    This study is the second in a series of publications by the Office of Education on school insurance. Data for this study were adapted from many sources. Among these sources were books of a technical nature, professional magazine articles, State insurance guides, research studies, insurance rating schedules, insurance company bulletins, and…

  14. Bulletin of Materials Science | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Bulletin of Materials Science; Volume 40; Issue 3. Effect of composition on the polarization and ohmic resistances of LSM/YSZ composite cathodes in solid oxide fuel cell. B SHRI PRAKASH S SENTHIL KUMAR S T ARUNA. Volume 40 Issue 3 June 2017 pp 441-452 ...

  15. Bulletin of Materials Science | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Bulletin of Materials Science; Volume 29; Issue 5 ... Polyester urethane; scaffold; tensile strength; swelling; degradation; cell culture. ... Materials Science Centre, Indian Institute of Technology, Kharagpur 721 302, India; School of Medical Science and Technology, Indian Institute of Technology, Kharagpur ...

  16. Bulletin of Materials Science | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Bulletin of Materials Science; Volume 34; Issue 6 ... by microwave route and nature of anatase–rutile phase transition in nano TiO2 .... properties of AgPb10SbTe12 prepared by high pressure method .... the crystal field strength around Mn(V) such that a blue colour results for materials with small values of .

  17. Power Transformers: Technical Terminology Bulletin. Terminotech, Vol.2, No. 6.

    Science.gov (United States)

    General Electric Co. of Canada, Ltd., Montreal, Quebec.

    This issue of a bulletin of technological terminology is devoted to power transformers. A brief narrative on the subject is presented in both French and English. An English-French dictionary of terms comprises the bulk of the document. Explanatory illustrations are appended. (JB)

  18. Bulletin of Materials Science | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Bulletin of Materials Science; Volume 31; Issue 6 .... modified with 4–12% 3,3′-bis(maleimidophenyl) phenylphosphine oxide and cured ... Study of effect of composition, irradiation and quenching on ionic ... Application of magnetron sputtering for producing bioactive ceramic coatings on implant materials.

  19. More Firepower for Health Education. Bulletin, 1945, No. 2

    Science.gov (United States)

    Steinhaus, Arthur H.

    1945-01-01

    This bulletin is committed to the thesis that the success of any educative experience varies as thoughts are or are not accompanied by appropriate feelings; that education must ever be alert to both of these happenings; and that the teacher can influence the feeling phase of an experience even as he can the cognitive phase. In limiting its efforts…

  20. Bullying in Schools: An Overview. Juvenile Justice Bulletin

    Science.gov (United States)

    Seeley, Ken; Tombari, Martin L.; Bennett, Laurie J.; Dunkle, Jason B.

    2011-01-01

    Researchers from the National Center for School Engagement conducted a series of studies to explore the connections between bullying in schools, school attendance and engagement, and academic achievement. This bulletin provides an overview of the studies funded by the Office of Juvenile Justice and Delinquency Prevention (OJJDP), a summary of the…

  1. Bulletin of Materials Science | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Bulletin of Materials Science; Volume 28; Issue 2. Effect of annealing temperature on the structural–microstructural and electrical characteristics of thallium bearing HTSC films prepared by chemical spray pyrolysis technique. K K Verma R S Tiwari O N Srivastava. Superconductors Volume 28 Issue 2 April ...

  2. Bulletin of Materials Science | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Bulletin of Materials Science; Volume 41; Issue 2. Effect of oxygen vacancies on Li-storage of anatase TiO 2 (001) facets: a first principles study. H CHEN Y H DING X Q TANG W ZHANG J R YIN P ZHANG Y JIANG. Volume 41 Issue 2 April 2018 Article ID 51 ...

  3. Bulletin of Materials Science | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Bulletin of Materials Science; Volume 35; Issue 4. CuO/TiO2 nanocrystals grown on graphene as visible-light responsive photocatalytic hybrid materials. Yuan Fang Rijing Wang Guohua Jiang He Jin Yin Wang Xinke Sun Sheng Wang Tao Wang. Volume 35 Issue 4 August 2012 pp 495-499 ...

  4. Bulletin of Materials Science | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Bulletin of Materials Science; Volume 24; Issue 6. Tailoring magnetic and dielectric properties of rubber ferrite composites containing mixed ferrites. M R Anantharaman K A Malini S Sindhu E M Mohammed S K Date S D Kulkarni P A Joy Philip Kurian. Magnetic Materials Volume 24 Issue 6 December 2001 ...

  5. Bulletin of Materials Science | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Bulletin of Materials Science; Volume 37; Issue 4. Structural, spectroscopic and electrochemical study of V5+ substituted LiTi2(PO4)3 solid electrolyte for lithium-ion batteries. A Venkateswara Rao V Veeraiah A V Prasada Rao B Kishore Babu B Swarna Latha K Rama Rao. Volume 37 Issue 4 June 2014 pp ...

  6. Bulletin of Materials Science | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Special Issues. Bulletin of Materials Science. pp 199-584 Volume 31 Issue 3 June 2008. Proceedings of the 'National Review and Coordination Meeting on Nanoscience and Nanotechnology', Hyderabad, 2007. Editor: S. B. Krupanidhi Guest Editors: G. Sundararajan and Tata Narasinga Rao. pp 547-651 Volume 29 Issue ...

  7. Bulletin of Materials Science | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    ... Bulletin of Materials Science; Volume 29; Issue 2. Mechanism of cube grain nucleation during recrystallization of deformed commercial purity aluminium. K T Kashyap R George. Nucleation Studies Volume 29 Issue ... Keywords. Recrystallization; cube texture; commercial purity aluminium; differential stored energy model.

  8. Bulletin of Materials Science | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Bulletin of Materials Science; Volume 39; Issue 5. Structure and magnetic properties of Zr–Mn substituted strontium hexaferrite Sr(Zr,Mn) x Fe 12 − 2 x O 19 nanoparticles synthesized by sol–gel auto-combustion method. S ALAMOLHODA S M MIRKAZEMI Z GHIAMI M NIYAIFAR. Volume 39 Issue 5 ...

  9. Bulletin of Materials Science | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Articles written in Bulletin of Materials Science. Volume ... Preparation and characterization of magnesium–aluminium–silicate glass ceramics ... Preparation and studies of some thermal, mechanical and optical properties of .... Surface degradation behaviour of sodium borophosphate glass in aqueous media: Some studies.

  10. Bulletin of Materials Science | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Bulletin of Materials Science; Volume 35; Issue 5 .... Influence of different heat treatment programs on properties of sol–gel ... The strong preferred c-axis orientation is lost due to cadmium doping and degree ... Electrical transport and EPR investigations: A comparative study for d.c. conduction mechanism in ...

  11. Iron Metallurgy: Technical Terminology Bulletin. Terminotech, Vol. 2, No. 7.

    Science.gov (United States)

    General Electric Co. of Canada, Ltd., Montreal, Quebec.

    This issue of a bulletin of technological terminology is devoted to iron metallurgy. Various aspects of iron production are described in both French and English. An English-French dictionary of terms comprises the bulk of the document. Explanatory illustrations are appended. (JB)

  12. Petersburg Builds a Health Program. Bulletin, 1949, No. 9

    Science.gov (United States)

    Bathurst, Effie G.

    1949-01-01

    This bulletin is about an invasion that was welcomed. It tells how boys and girls of Petersburg, West Virginia, invaded their town to learn and to serve. Hotels, school lunchroom, alleys, creeks and swamps, unused park area, and other resources were utilized. The young invaders were welcomed by the adult citizens of the town because the principal…

  13. Bulletin of Materials Science | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Bulletin of Materials Science; Volume 40; Issue 4 ... Nacional de Investigaciones Científicas y Técnicas), A4408FVY Salta, Argentina; Fac. Ingeniería, Universidad Nacional de Salta, A4408FVY Salta, Argentina; Fac.

  14. Three flavonol glycosides from Ricinus communis | Aqil | Bulletin of ...

    African Journals Online (AJOL)

    Bulletin of the Chemical Society of Ethiopia. Journal Home · ABOUT THIS JOURNAL · Advanced Search · Current Issue · Archives · Journal Home > Vol 11, No 1 (1997) >. Log in or Register to get access to full text downloads. Username, Password, Remember me, or Register. Three flavonol glycosides from Ricinus ...

  15. Bulletin of Materials Science | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    ... Lecture Workshops · Refresher Courses · Symposia · Live Streaming. Home; Journals; Bulletin of Materials Science; Volume 29; Issue 4. Acoustic study of nano-crystal embedded PbO–P2O5 glass. Sudip K Batabyal A Paul P Roychoudhury C Basu. Ceramics and Glasses Volume 29 Issue 4 August 2006 pp 357-363 ...

  16. Bulletin of Materials Science | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Bulletin of Materials Science; Volume 29; Issue 4. Impedance and a.c. conductivity studies on Ba(Nd0.2Ti0.6Nb0.2)O3 ceramic prepared through conventional and microwave sintering route. Syed Mahboob G Prasad G S Kumar. Ceramics and Glasses Volume 29 Issue 4 August 2006 pp 347-355 ...

  17. Bulletin of Materials Science | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Bulletin of Materials Science; Volume 23; Issue 4. Phase analysis and dielectric properties of ceramics in PbO–MgO–ZnO–Nb2O5 system: A comparative study of materials obtained by ceramic and molten salt synthesis routes. M Thirumal A K Ganguli. Ceramics Volume 23 Issue 4 August 2000 pp 255-261 ...

  18. Bulletin of Materials Science | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Bulletin of Materials Science; Volume 30; Issue 4 ... Microwave materials; ceramic dielectric resonators; polytitanates; co-precipitation. ... hypotheses viz. diffusion, high surface and nucleation energy, potential barrier, non-stoichiometry etc as critical factors limiting formation of 2 : 9 as single-phase material.

  19. Bulletin of Materials Science | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Bulletin of Materials Science; Volume 29; Issue 2. Thermoluminescence dosimetry of rare earth doped calcium aluminate phosphors. K Madhukumar K Rajendra Babu K C Ajith Prasad J James T S Elias V Padmanabhan C M K Nair. Ceramics and Glasses Volume 29 Issue 2 April 2006 pp 119-122 ...

  20. Botanical aspects of aloes of north East Africa | Demissew | Bulletin ...

    African Journals Online (AJOL)

    Bulletin of the Chemical Society of Ethiopia. Journal Home · ABOUT THIS JOURNAL · Advanced Search · Current Issue · Archives · Journal Home > Vol 10, No 1 (1996) >. Log in or Register to get access to full text downloads. Username, Password, Remember me, or Register. Botanical aspects of aloes of north East Africa.