WorldWideScience

Sample records for monthly progress status

  1. Progress report, 24 months

    DEFF Research Database (Denmark)

    Juhl, Thomas Winther; Nielsen, Jakob Skov

    The work performed during the past 12 months (months 13 – 24) of the project has included the conclusion of Task 1 – Fundamental Studies and Task 2 – Multimirror Cutting Head Design. Work on Task 3 – Compact Cutting Head Design, and Task 4 – Interface Design has been carried out and the tests...... of the multimirror cutting head have been started....

  2. Progress report, 36 months

    DEFF Research Database (Denmark)

    Juhl, Thomas Winther; Nielsen, Jakob Skov

    The work performed during the past 12 months (months 13 – 24) of the project has included the conclusion of Task 1 – Fundamental Studies and Task 2 – Multimirror Cutting Head Design. Work on Task 3 – Compact Cutting Head Design, and Task 4 – Interface Design has been carried out and the tests...... of the multimirror cutting head have been started....

  3. Monthly progress report

    International Nuclear Information System (INIS)

    1975-06-01

    This monthly report of the SCPRI exposes an interpretation of the principal results concerning the surveillance of radioactivity in the environment: atmospheric dusts(air at ground level, high altitude air), rainwater, surface water, underground water, irrigation water, drinking water, food chain (milk, plants, cattle, fish), sea water around nuclear plant sites and other sites. The activities of various radioisotopes are presented in tables ( 7 Be, 95 Zr and 95 Nb, 103 Ru, 131 I, 137 Cs, 140 Ba and 140 La, 90 Sr, 106 Ru and 106 Rh, 226 Ra, 54 Mn, U and T). A monthly bibliographic selection is also presented [fr

  4. Monthly progress report

    International Nuclear Information System (INIS)

    1975-03-01

    This monthly report of the SCPRI exposes an interpretation of the principal results concerning the surveillance of radioactivity in the environment: atmospheric dusts (air at ground level, high altitude air), rainwater, surface water, underground water, irrigation water, drinking water, food chain (milk, plants, cattle, fish), sea water around nuclear plant sites and other sites. The activities of various radioisotopes are presented in tables ( 7 Be, 95 Zr and 95 Nb, 103 Ru, 131 I, 137 Cs, 140 Ba and 140 La, 90 Sr, 106 Ru and 106 Rh, 226 Ra, 54 Mn, U and T). A monthly bibliographic selection is also presented [fr

  5. Monthly progress report

    International Nuclear Information System (INIS)

    1975-04-01

    This monthly report of the SCPRI exposes an interpretation of the principal results concerning the surveillance of radioactivity in the environment: atmospheric dusts (air at ground level, high altitude air), rainwater, surface water, underground water, irrigation water, drinking water, food chain (milk plants, cattle, fish), seawater around nuclear plant sites and other sites. The activities of various radioisotopes are presented in tables ( 7 Be, 95 Zr and 95 Nb, 103 Ru, 131 I, 137 Cs, 140 Ba and 140 La, 90 Sr, 106 Ru and 106 Rh, 226 Ra, 54 Mn U and T). A monthly bibliographic selection is also presented [fr

  6. Monthly progress report

    International Nuclear Information System (INIS)

    1975-01-01

    This monthly report of the SCPRI exposes an interpretation of the principal results concerning the surveillance of radioactivity in the environment: atmospheric dusts (air at ground level, high altitude air), rainwater, surface water, underground water, irrigation water, drinking water, food chain (milk, plants, cattle, fish), sea water around nuclear plant sites and other sites. The activities of various radioisotopes are presented in tables ( 7 Be, 95 Zr and 95 Nb, 103 Ru, 131 I, 137 Cs, 140 Ba and 140 La, 90 Sr, 106 Ru and 106 Rh, 226 Ra, 54 Mn, U and T). A monthly bibliographic selection is also presented [fr

  7. Monthly progress report

    International Nuclear Information System (INIS)

    1975-02-01

    This monthly report of the SCPRI exposes an interpretation of the principal results concerning the surveillance of radioactivity in the environment: atmospheric dusts (air at ground level, high altitude air), rainwater, surface water, underground water, irrigation water, drinking water, food chain (milk, plants, cattle, fish), sea water around nuclear plant sites and other sites. The activities of various radioisotopes are presented in tables ( 7 Be, 95 Zr and 95 Nb, 103 Ru, 131 I, 137 Cs, 140 Ba and 140 La, 90 Sr, 106 Ru and 106 Rh, 226 Ra, 54 Mn, U and T). A monthly bibliographic selection is also presented [fr

  8. Periodic progress report, 6 months

    DEFF Research Database (Denmark)

    Juhl, Thomas Winther; Nielsen, Jakob Skov

    This is the first progress report of the BriteEuram project named "High Power Laser Cutting for Heavy Industry" ("Powercut"). The report contains a summary of the objectives of the first period, an overview of the technical progress, a comparison between the planed and the accomplished work...

  9. Periodic progress report, 12 months

    DEFF Research Database (Denmark)

    Juhl, Thomas Winther; Nielsen, Jakob Skov

    The work performed during the first 12 months of the project started with the establishment of the cutting theory for the cutting of heavy sections (phase 1). Phase 2 comprises the design of the first laboratory version cutting head with optics, nozzle systems and interfaces for the various...

  10. Monthly progress report: Heat source technology program

    Energy Technology Data Exchange (ETDEWEB)

    George, T.G. [comp.

    1993-05-01

    This monthly report describes activities performed in support of Cassini fueled-clad production and studies related to the use of {sup 238}PuO{sub 2} in radioisotope power systems carried out for the Office of Special Applications of the US Department of Energy (DOE) by Los Alamos National Laboratory (LANL). Most of the activities described are ongoing; the results and conclusions described may change as the work progresses.

  11. Monthly oral methylprednisolone pulse treatment in progressive multiple sclerosis

    DEFF Research Database (Denmark)

    Ratzer, Rikke; Iversen, Pernille; Börnsen, Lars

    2016-01-01

    BACKGROUND: There is a large unmet need for treatments for patients with progressive multiple sclerosis (MS). Phase 2 studies with cerebrospinal fluid (CSF) biomarker outcomes may be well suited for the initial evaluation of efficacious treatments. OBJECTIVE: To evaluate the effect of monthly oral...... methylprednisolone pulse treatment on intrathecal inflammation in progressive MS. METHODS: In this open-label phase 2A study, 15 primary progressive and 15 secondary progressive MS patients received oral methylprednisolone pulse treatment for 60 weeks. Primary outcome was changes in CSF concentrations of osteopontin...... no change in the CSF concentration of osteopontin, but we observed significant improvement in clinical scores, MTR, DTI and some secondary CSF outcome measures. Adverse events were well-known side effects to methylprednisolone. CONCLUSION: Monthly methylprednisolone pulse treatment was safe, but had...

  12. Monthly oral methylprednisolone pulse treatment in progressive multiple sclerosis.

    Science.gov (United States)

    Ratzer, Rikke; Iversen, Pernille; Börnsen, Lars; Dyrby, Tim B; Romme Christensen, Jeppe; Ammitzbøll, Cecilie; Madsen, Camilla Gøbel; Garde, Ellen; Lyksborg, Mark; Andersen, Birgit; Hyldstrup, Lars; Sørensen, Per Soelberg; Siebner, Hartwig R; Sellebjerg, Finn

    2016-06-01

    There is a large unmet need for treatments for patients with progressive multiple sclerosis (MS). Phase 2 studies with cerebrospinal fluid (CSF) biomarker outcomes may be well suited for the initial evaluation of efficacious treatments. To evaluate the effect of monthly oral methylprednisolone pulse treatment on intrathecal inflammation in progressive MS. In this open-label phase 2A study, 15 primary progressive and 15 secondary progressive MS patients received oral methylprednisolone pulse treatment for 60 weeks. Primary outcome was changes in CSF concentrations of osteopontin. Secondary outcomes were other CSF biomarkers of inflammation, axonal damage and demyelination; clinical scores; magnetic resonance imaging measures of disease activity, magnetization transfer ratio (MTR) and diffusion tensor imaging (DTI); motor evoked potentials; and bone density scans. We found no change in the CSF concentration of osteopontin, but we observed significant improvement in clinical scores, MTR, DTI and some secondary CSF outcome measures. Adverse events were well-known side effects to methylprednisolone. Monthly methylprednisolone pulse treatment was safe, but had no effect on the primary outcome. However, improvements in secondary clinical and MRI outcome measures suggest that this treatment regimen may have a beneficial effect in progressive MS. © The Author(s), 2015.

  13. Heat source technology programs. Monthly progress report, March 1995

    International Nuclear Information System (INIS)

    Tomlinson, L.J.

    1996-02-01

    This monthly report describes activities performed in support of Cassini fueled-clad production and studies related to the use of 238 PuO 2 in radioisotope power systems carried out for the Office of Special Applications of the US Department of Energy (DOE) by Los Alamos National Laboratory (LANL). Most of the activities described are ongoing; the results and conclusions described may change as the work progresses

  14. Improved nutritional status in elderly patients 6 months after stroke

    DEFF Research Database (Denmark)

    Brynningsen, P K; Damsgaard, Else Marie; Husted, Steen

    2007-01-01

    INTRODUCTION: Nutritional status among stroke patients has received limited attention despite the fact, that it may have an influence on clinical outcome. Previous studies have estimated that 15-20 % of patients suffer from malnutrition in the acute phase of stroke, but so far no studies have...... focused on the late rehabilitation phase after stroke in the patients own home, where the attention on nutrition may be reduced. AIMS: To determine the prevalence of malnutrition during 6 months of stroke rehabilitation, and to investigate the association between nutritional status, functional recovery...... improvement for serum proteins, and 22 % of the patients were malnourished 6 months after stroke. Udgivelsesdato: null-null...

  15. Improved nutritional status in elderly patients 6 months after stroke

    DEFF Research Database (Denmark)

    Brynningsen, Peter Krogh; Husted, Steen; Damsgaard, Else Marie Skjøde

    2007-01-01

    focused on the late rehabilitation phase after stroke in the patients own home, where the attention on nutrition may be reduced. AIMS: To determine the prevalence of malnutrition during 6 months of stroke rehabilitation, and to investigate the association between nutritional status, functional recovery......INTRODUCTION: Nutritional status among stroke patients has received limited attention despite the fact, that it may have an influence on clinical outcome. Previous studies have estimated that 15-20 % of patients suffer from malnutrition in the acute phase of stroke, but so far no studies have......, length of stay in hospital and infectious complications. SUBJECTS AND METHODS: 89 patients with ischemic stroke consecutively admitted to a geriatric stroke rehabilitation unit had their nutritional status evaluated in the hospital at 1 week and 5 weeks after stroke, and in their own home at 3 months...

  16. Improved nutritional status in elderly patients 6 months after stroke

    DEFF Research Database (Denmark)

    Brynningsen, P K; Damsgaard, Else Marie; Husted, Steen

    2007-01-01

    INTRODUCTION: Nutritional status among stroke patients has received limited attention despite the fact, that it may have an influence on clinical outcome. Previous studies have estimated that 15-20 % of patients suffer from malnutrition in the acute phase of stroke, but so far no studies have...... focused on the late rehabilitation phase after stroke in the patients own home, where the attention on nutrition may be reduced. AIMS: To determine the prevalence of malnutrition during 6 months of stroke rehabilitation, and to investigate the association between nutritional status, functional recovery...... and 6 months. Nutritional status was evaluated by body weight, body mass index (BMI), mid upper arm circumference (MAC), triceps skinfold thickness (TSF) and serum concentrations of albumin and transferrin. Malnutrition was defined if the patients had 2 or more abnormal nutritional variables. RESULTS...

  17. Vitamin D status in the first 9 months of life

    DEFF Research Database (Denmark)

    Thomsen, Súsanna við Streym

    2012-01-01

    D-vitamin mangel er udbredt også hos mødre og deres spædbørn. D-vitamin er vigtigt for udviklingen af skelettet, men kan også have betydning for andre organsystemer, såsom immunforsvaret og derved for forebyggelsen af infektioner og udvikling af autoimmune sygdomme, som multipel sklerose (MS), type...... 1 diabetes mellitus (T1DM), og i sidste ende kræft. For at uddybe disse forhold har jeg gennemført fire studier: 1) Maternal and infant vitamin D status during the first 9 months of infant life – a cohort study, 2) Peripheral Quantitative Computed Tomography (pQCT) of tibia in 9 month old infants......: Relations to gender and to maternal and infant plasma 25OHD and PTH levels, 3) The effect of season of birth on the later risk of infections and selected chronic diseases like MS, T1DM, cancer, schizophrenia, and acute myocardial infarct og 4) The stability of 25-hydroxyvitamin D in human blood during...

  18. Status and progress of the RERTR Program

    International Nuclear Information System (INIS)

    Travelli, A.

    1996-01-01

    The progress of the Reduced Enrichment Research and Test Reactor (RERTR) Program is described. The major events, findings, and activities of 1996 are reviewed after a brief summary of the results which the RERTR Program had achieved by the end of 1995 in collaboration with its many international partners

  19. Status and progress of the RERTR Program

    International Nuclear Information System (INIS)

    Travelli, A.

    1993-01-01

    The progress of the Reduced Enrichment Research and Test Reactor (RERTR) Program is described. The major events, findings, and activities of 1993 are reviewed after a brief summary of the results which the RERTR Program had achieved by the end of 1992 in collaboration with its many international partners

  20. Neutrino experiments: Status, recent progress, and prospects

    International Nuclear Information System (INIS)

    Brice, S

    2008-01-01

    Neutrino physics has seen an explosion of activity and new results in the last decade. In this report the current state of the field is summarized, with a particular focus on progress in the last two years. Prospects for the near term (roughly 5 years) are also described

  1. [Status quo and progress of Chinese acupuncture in Algeria].

    Science.gov (United States)

    Huang, Yisheng

    2015-10-01

    The development of Chinese acupuncture in Algeria and realistic working status in recent years is in- troduced. From five aspects, including general condition of acupuncture in Algeria, clinical application and analysis, of acupuncture, promotion and publicity of acupuncture, existing problem and deficiency, and awards and honor, the status quo and progress of Chinese acupuncture in Algeria are discussed in detail.

  2. Status and progress of the RERTR program

    International Nuclear Information System (INIS)

    Travelli, A.

    1996-01-01

    The progress of the Reduced Enrichment Research and Test Reactor (RERTR) Program is described. The major events, findings, and activities of 1996 are reviewed after a brief summary of the results which the RERTR Program had achieved by the end of 1995 in collaboration with its many international partners. Significant progress has been made during the past year in each of the three areas that the delegates to last year's RERTR meeting chose to address, in their letter to President Clinton, as requiring special attention. (1) In the area of U.S. acceptance of spent fuel from foreign research reactors, a second shipment of 99 urgent-relief spent fuel elements was completed. The Final Environmental Impact Statement was published in February 1996, and the Record of Decision was published in May 1996. The first shipments under the Record of Decision, containing 280 spent fuel elements, were received at the Savannah River Site in September 1996. (2) In the area of advanced fuel development, adequate funding and guidance were received by the RERTR program in March 1996. Fuel development activities are now in progress, including procurement of equipment, screening of candidate materials, and preparations for the production of a first series of microplates. The first irradiations are planned to begin in the Advanced Test Reactor. in Idaho, during April 1997. (3) In the area of conversion of DOE research reactors, the RERTR program has been tasked by the Department of Energy to assess the feasibility of converting to LEU fuel each of the DOE research reactors which currently use HEU fuel. A preliminary assessment will be presented at this meeting. Significant progress has been made by the Russian RERTR program, which aims to develop and demonstrate within the next five years the technical means needed to convert Russian-supplied research reactors to LEU fuels. The study of an alternative LEU core for the FRM-II design has been extended to address, with excellent results

  3. The RERTR program status and progress

    International Nuclear Information System (INIS)

    Travelli, A.

    2004-01-01

    The progress of the Reduced Enrichment Research and Test Reactor (RERTR) Program is described. The major events, findings, and activities of 1995 are reviewed after a brief summary of the results which the RERTR Program had achieved by the end of 994 in collaboration with its many international partners. The revelation that Iraq was on the verge of developing a nuclear weapon at the time of the Gulf War, and that it was planning to do so by extracting HEU from the fuel of its research reactors, has given new impetus and urgency to the RERTR commitment of eliminating HEU use in research and test reactors worldwide. The Draft Environmental Impact Statement on the DOE policy for managing spent nuclear fuels from foreign research reactors was published on schedule. A Record of Decision is due in December 1995. After much legal debate, a first shipment of 153 urgent-relief elements took place, and another 151 elements became eligible for shipment. Development of advanced LEU research reactor fuels is scheduled to begin in October 1995, after DOE funding is received. Funding for equipment needed to begin this activity was provided by the US Department of State, and procurement of the equipment is in progress. The Russian RERTR program, which aims to develop and demonstrate within the next five years the technical means needed to convert Russian-supplied research reactors to LEU fuels, is now in operation. A Statement of Intent was signed by high US and Chinese officials, endorsing cooperative activities between the RERTR program and Chinese laboratories involved in similar activities. Joint studies of LEU technical feasibility were completed for the SAFARI-1 reactor in South Africa and for the ANS reactor in the US. The ANS project was later canceled for budgetary and nonproliferation reasons. A new study has been initiated for the FRM-II reactor in Germany. Significant progress was made on several aspects of producing 99 Mo from fission targets utilizing LEU instead of

  4. Infectious pleural effusion status and treatment progress

    Science.gov (United States)

    Yang, Wei; Zhang, Ze-Ming

    2017-01-01

    Pleural cavity infection continuously seriously threatens human health with continuous medical progress. From the perspective of pathophysiology, it can be divided into three stages: exudative stage, fibrin exudation and pus formation stage, and organization stage. Due to the pathogenic bacteria difference of pleural cavity infection and pulmonary infection, it is very important for disease treatment to analyze the bacteria and biochemical characteristics of the infectious pleural effusion. Most prognoses of patients have been relatively good, while for some patients, the complicated parapneumonic effusion or empyema could be evolved. Antibiotic treatment and sufficient drainage are the foundation for this treatment. No evidence can support the routine use of a fibrin agent. However, it has been reported that the plasminogen activator and deoxyribonuclease can be recommended to be applied in the pleural cavity. In case of failure on conservative medical treatment, operative treatment can be applied such as thoracoscopy and pleural decortication. According to the clinical characteristics of these patients, it is a key to research prognosis, as well as early evaluation and stratification, in the future. PMID:29268539

  5. Rehabilitation status three months after first-time myocardial infarction

    DEFF Research Database (Denmark)

    Larsen, Karen Kjær; Vestergaard, Mogens; Søndergaard, Jens

    2011-01-01

    (76.4%) clopidogrel, 756 (83.3%) statins, and 735 (81.0%) beta-blockers. Conclusion. After three months, there is a considerable potential for further rehabilitation of MI patients. In particular, the long-term CR should focus on mental health, smoking cessation, and cardioprotective drugs....... less than 10 years of education. Upwards of half (58.5%) of the patients stated that they had participated in hospital-based rehabilitation shortly after admission. A total of 262 (29.2%) were identifi ed with anxiety or depressive disorder or both, according to the Hospital Anxiety and Depression...

  6. National Ignition Facility monthly status report--February 2000

    International Nuclear Information System (INIS)

    Moses, E

    2000-01-01

    The Project provides for the design, procurement, construction, assembly, installation, and acceptance testing of the National Ignition Facility (NIF), an experimental inertial confinement fusion facility intended to achieve controlled thermonuclear fusion in the laboratory by imploding a small capsule containing a mixture of the hydrogen isotopes deuterium and tritium. The NIF will be constructed at the Lawrence Livermore National Laboratory (LLNL), Livermore, California as determined by the Record of Decision made on December 19, 1996, as a part of the Stockpile Stewardship and Management Programmatic Environmental Impact Statement. Safety: The Incident Analysis and Construction Management Safety Review Teams were formed to review the January 13, 2000, accident in which a worker received a back injury when a 42-in.-diameter duct fell during installation. One action is to contract DuPont to review the Safety Program. Technical Status: The general status of the technologies underlying the NIF Project remains satisfactory. The issues currently being addressed are (1) cleanliness for installation, assembly, and activation of the laser system by Systems Engineering; (2) laser glass--a second pilot run at one of the two commercial suppliers is ongoing successfully; and (3) operational costs associated with final optics assembly (FOA) optics components--methods are being developed to mitigate 3ω damage and to resolve beam rotation issues. Schedule: The completion of the Title II design of laser equipment is now approximately 83% complete. The Beampath Infrastructure System is on the critical schedule path. The procurement strategy was evaluated by commercial construction management and Architectural/Engineering (A/E) contractors with a panel of independent experts, the Beampath Infrastructure System (BIS) Implementation Review Committee Advisory Group. The BIS Integration Management and Installation Services (IMI) Subcontractor solicitation package and approach were

  7. National Ignition Facility monthly status report-January 2000

    International Nuclear Information System (INIS)

    Moses, E

    2000-01-01

    The Project provides for the design, procurement, construction, assembly, installation, and acceptance testing of the National Ignition Facility (NIF), an experimental inertial confinement fusion facility intended to achieve controlled thermonuclear fusion in the laboratory by imploding a small capsule containing a mixture of the hydrogen isotopes deuterium and tritium. The NIF will be constructed at the Lawrence Livermore National Laboratory (LLNL), Livermore, California as determined by the Record of Decision made on December 19, 1996, as a part of the Stockpile Stewardship and Management Programmatic Environmental Impact Statement. Safety: On January 13, 2000, a worker received a back injury when a 42-in.-diameter duct fell during installation. He was taken by helicopter to the hospital and released on January 16, 2000. All work in the area was suspended, and the construction contractors went through a thorough safety review before work was started. A DOE occurrence report was filed. An independent LLNL Incident Analysis Team is reviewing the cause of the accident and will report out on March 1. A Project management review team is reviewing construction line management and safety support and will also report out on March 1. Several changes in work planning and site management have been incorporated to increase site safety. Technical Status: The general status of the technologies underlying the NIF Project remains satisfactory. The issues currently being addressed are (1) cleanliness for installation, assembly, and activation of the laser system by Systems Engineering; (2) laser glass--a second pilot run at one of the two commercial suppliers is ongoing; and (3) operational costs associated with final optics assembly (FOA) optics components--methods are being developed to mitigate 3 ωdamage and resolve beam rotation issues. Schedule: The completion of the Title II design of laser equipment is now approximately 80% complete. The Beampath Infrastructure System is

  8. Progress, status, and plans for the HRIBF project

    International Nuclear Information System (INIS)

    Auble, R.L.; Alton, G.D.; Bailey, J.D.

    1995-01-01

    Over the last three years, the Holifield accelerator system has been reconfigured into a first-generation radioactive ion beam facility, the HRIBF, a national user facility for RIB research. The construction and reconfiguration have been completed and the equipment commissioning and beam development phases have started. The progress to date, the present status, and future plans will be given. The special problems connected with the production and acceleration of RIBs will be discussed

  9. Cassini RTG Program. Monthly technical progress report, 27 November--31 December 1995

    International Nuclear Information System (INIS)

    1996-01-01

    This monthly technical progress report provided information on the following tasks: spacecraft integration and liaison; engineering support; safety analysis; qualified unicouple fabrication; ETG fabrication, assembly, and test; ground support equipment (GSE); RTG shipping and launch support; designs, reviews, and mission applications; project management, quality assurance, and reliability, and contractor acquired government owned (CAGO) property acquisition

  10. HIV status, breastfeeding modality at 5 months and postpartum maternal weight changes over 24 months in rural South Africa.

    Science.gov (United States)

    Chetty, Terusha; Carter, Rosalind J; Bland, Ruth M; Newell, Marie-Louise

    2014-07-01

    To determine the effect of infant feeding practices on postpartum weight change among HIV-infected and -uninfected women in South Africa. In a non-randomised intervention cohort study of antiretroviral therapy-naïve women in South Africa, infants were classified as exclusive (EBF), mixed (MF) or non-breastfed (NBF) at each visit. We analysed infant feeding cumulatively from birth to 5 months using 24-hour feeding history (collected weekly for each of the preceding 7 days). Using generalised estimating equation mixed models, allowing for repeated measures, we compared postpartum weight change (kg) from the first maternal postpartum weight within the first 6 weeks (baseline weight) to each subsequent visit through 24 months among 2340 HIV-infected and -uninfected women with live births and at least two postpartum weight measurements. HIV-infected (-0.2 kg CI: -1.7 to 1.3 kg; P = 0.81) and -uninfected women (-0.5 kg; 95% CI: -2.1 to 1.2 kg; P = 0.58) had marginal non-significant weight loss from baseline to 24 months postpartum. Adjusting for HIV status, socio-demographic, pregnancy-related and infant factors, 5-month feeding modality was not significantly associated with postpartum weight change: weight change by 24 months postpartum, compared to the change in the reference EBF group, was 0.03 kg in NBF (95% CI: -2.5 to +2.5 kg; P = 0.90) and 0.1 kg in MF (95% CI: -3.0 to +3.2 kg; P = 0.78). HIV-infected and -uninfected women experienced similar weight loss over 24 months. Weight change postpartum was not associated with 5-month breastfeeding modality among HIV-infected and -uninfected women. © 2014 John Wiley & Sons Ltd.

  11. Effects of Nutritional Status on 6-Month Outcome of Hip Fractures in Elderly Patients

    OpenAIRE

    Miu, Ka Ying Doris; Lam, Pui Shan

    2017-01-01

    Objective To identify the prevalence of malnutrition in elderly hip fracture and to investigate the relationship between hip fracture patients and malnutrition on functional recovery and mortality. Methods All hip fracture patients age >65 years admitted to a rehabilitation unit were recruited from July 2015 to June 2016. Nutritional status was assessed by Mini-Nutritional Assessment Short-Form (MNA-SF) within 72 hours of admission. Patients were reassessed at 6 months for functional status a...

  12. Status and Recent Progress in Photovoltaic Manufacturing in the USA

    Energy Technology Data Exchange (ETDEWEB)

    Witt, C.E.

    2001-01-12

    This paper describes the present status of photovoltaic technology and recent manufacturing progress obtained through the US Department of Energy's Photovoltaic Manufacturing Technology Project (PVMaT). Although barriers to the widespread use of photovoltaics--a clean and renewable energy--continue to exist, many of these barriers are cost-related and can be addressed through further research on existing approaches. Important areas for development are new materials, improved manufacturing processes, more efficient conversion of sunlight to electricity, and ensured long-term reliability. Improvements in these areas can be expected to lead to lowering of system costs and, ultimately, of energy cost. Specific improvements in manufacturing processes by individual PVMaT participants are described.

  13. Russian section of GGOS: Network status and progress

    Directory of Open Access Journals (Sweden)

    A. Ipatov

    2017-03-01

    Full Text Available Establishment of the Russian section in the framework of Global Geodetic Observing System (GGOS is under progress. New components of “Quasar” network observatories, which are included into GGOS global network as core stations, are presented. Recent developments include: two new generation radio telescopes with 13 m antennas at Badary and Zelenchukskaya observatories, water vapor radiometers installed at all observatories and software correlator at the Institute of Applied Astronomy. New and potential developments within other networks belonging to different agencies are also considered in the context of widening of Russian section activity in GGOS project. The paper gives a short overview of status, new components and plans, concerning 5 sub-networks of Federal Agency of Scientific Organizations, Roskosmos, Rosstandard, and Rosreestr. Short overview of the plans on creating Data and Analysis Distributed Center is also given.

  14. Status of the RERTR program: overview, progress and plans

    International Nuclear Information System (INIS)

    Travelli, A.

    1985-01-01

    The status of the US Reduced Enrichment Research and Test Reactor (RERTR) Program is reviewed. After a summary of the accomplishments which the RERTR Program had achieved by the end of 1984 with its many international partners, emphasis is placed on the progress achieved during 1985 and on current plans and schedules. A new miniplate series, concentrating on U 3 Si 2 -Al and U 3 Si-Al fuels, was fabricated and is well into irradiation. The whole-core ORR demonstration is scheduled to begin in November 1985, with U 3 Si 2 -Al fuel at 4.8 g U/cm 3 . Altogether, 921 full-size test and prototype elements have been ordered for fabrication with reduced enrichment and the new technologies. Qualification of U 3 Si-Al fuel with approx.7 g U/cm 3 is still projected for 1989. This progress could not have been achieved without the close international cooperation which has existed since the beginning, and whose continuation and intensification will be essential to the achievement of the long-term RERTR goals

  15. The status of the RERTR Program: Overview, progress and plans

    International Nuclear Information System (INIS)

    Travelli, A.

    1985-01-01

    The status of the U.S. Reduced Enrichment Research and Test Reactor (RERTR) Program is reviewed. After a summary of the accomplishments which the RERTR Program had achieved by the end of 1984 with its many international partners, emphasis is placed on the progress achieved during 1985 and on current plans and schedules. A new miniplate series, concentrating on U 3 Si 2 -AI and U 3 Si-AI fuels, was fabricated and is well into irradiation. The whole-core ORR demonstration is scheduled to begin in November 1985, with U 3 Si 2 -AI fuel at 4.8 g U/cm 3 . Altogether, 921 full-size test and prototype elements have been ordered for fabrication with reduced enrichment and the new technologies. Qualification of U 3 Si-AI fuel with ∼7 g U/cm 3 is still projected for 1989. This progress could not have been achieved without the close international cooperation which has existed since the beginning, and whose continuation and intensification will be essential to the achievement of the long-term RERTR goals. (author)

  16. Mini Nutritional Assessment predicts gait status and mortality 6 months after hip fracture.

    Science.gov (United States)

    Gumieiro, David N; Rafacho, Bruna P M; Gonçalves, Andrea F; Tanni, Suzana E; Azevedo, Paula S; Sakane, Daniel T; Carneiro, Carlos A S; Gaspardo, David; Zornoff, Leonardo A M; Pereira, Gilberto J C; Paiva, Sergio A R; Minicucci, Marcos F

    2013-05-01

    The aim of the present study was to evaluate the Mini Nutritional Assessment (MNA), the Nutritional Risk Screening (NRS) 2002 and the American Society of Anesthesiologists Physical Status Score (ASA) as predictors of gait status and mortality 6 months after hip fracture. A total of eighty-eight consecutive patients over the age of 65 years with hip fracture admitted to an orthopaedic unit were prospectively evaluated. Within the first 72 h of admission, each patient's characteristics were recorded, and the MNA, the NRS 2002 and the ASA were performed. Gait status and mortality were evaluated 6 months after hip fracture. Of the total patients, two were excluded because of pathological fractures. The remaining eighty-six patients (aged 80·2 (sd 7·3) years) were studied. Among these patients 76·7 % were female, 69·8 % walked with or without support and 12·8 % died 6 months after the fracture. In a multivariate analysis, only the MNA was associated with gait status 6 months after hip fracture (OR 0·773, 95 % CI 0·663, 0·901; P= 0·001). In the Cox regression model, only the MNA was associated with mortality 6 months after hip fracture (hazard ratio 0·869, 95 % CI 0·757, 0·998; P= 0·04). In conclusion, the MNA best predicts gait status and mortality 6 months after hip fracture. These results suggest that the MNA should be included in the clinical stratification of patients with hip fracture to identify and treat malnutrition in order to improve the outcomes.

  17. Infant and child feeding index and nutritional status of 0-24 month ...

    African Journals Online (AJOL)

    Method: A cross sectional study was carried out to assess infant feeding practices of mothers and its effect on child nutritional status. A multistage random sampling procedure was used to select 450 mothers of children between the ages of 0-24 months. Breastfeeding and complementary feeding practices were examined ...

  18. Progress and present status of ITER cryoline system

    International Nuclear Information System (INIS)

    Badgujar, S.; Bonneton, M.; Chalifour, M.; Forgeas, A.; Serio, L.; Sarkar, B.; Shah, N.

    2014-01-01

    The cryoline system at ITER forms a very complex network localized inside the Tokamak building, on a dedicated plant bridge and in cryoplant areas. The cooling power produced in the cryoplant is distributed via these lines with a total length of about 3.7 km and interconnecting all the cold boxes of the cryogenic system as well as the cold boxes of various clients (magnets, cryopumps and thermal shield). Distinct layouts and polygonal geometry, nuclear safety and confinement requirements, difficult installation and in-service inspection/repair demand very high reliability and availability for the cryolines. The finalization of the building-embedded plates for supporting the lines, before the detailed design, has made this project technologically more challenging. The conceptual design phase has been completed and procurement arrangements have been signed with India, responsible for providing the system of cryolines and warm lines to ITER, as in kind contribution. The prototype test for the design and performance validation has been planned on a representative cryoline section. After describing the basic features and general layout of the ITER cryolines, the paper presents key design requirements, conceptual design approach, progress and status of the cryolines project as well as challenges to build such a complex cryoline system

  19. STATUS REPORT ON THE SIX-MONTH STUDY ON HIGH ENERGY MUON COLLIDERS

    International Nuclear Information System (INIS)

    KING, B.J.

    2001-01-01

    The structure, study topics, straw-man muon collider parameter sets and technical challenges for ''Six-Month Study on High Energy Muon Colliders: Oct'00-Apr'0l'' have been summarized at one month from completion of the study. The extremely high constituent particle energies and luminosities of the parameter sets presented in table 1 continue to suggest that muon colliders could play a central role in exploring and extending the HEP energy frontier. The study has already resulted in encouraging progress in areas such as the final focus lattice design and cost-efficient acceleration

  20. Dietary practices and nutritional status of 0-24-month-old children from Brazilian Amazonia.

    Science.gov (United States)

    Castro, T G; Baraldi, L G; Muniz, P T; Cardoso, M A

    2009-12-01

    To assess the nutritional status and dietary practices of 0-24-month-old children living in Brazilian Amazonia. Cross-sectional study. Information on children's dietary intakes was obtained from diet history data. Weight and length were measured for anthropometric evaluation. Fe status was assessed using fasting venous blood samples; Hb, serum ferritin and soluble transferrin receptor concentrations were measured. The towns of Assis Brasil and Acrelândia in the state of Acre, north-west Brazil. A total of sixty-nine randomly selected 0-24-month-old children. Of these children, 40.3 % were anaemic, 63.1 % were Fe-deficient, 28.1 % had Fe-deficiency anaemia and 11.6 % were stunted. Breast-feeding was initiated by 97.1 % of mothers, followed by early feeding with complementary foods. The dietary pattern reflected a high intake of carbohydrate-rich foods and cow's milk, with irregular intakes of fruit, vegetables and meat. All infants and 92.3 % of toddlers were at risk of inadequate Fe intakes. Fe from animal foods contributed on average 0.5 % and 14.3 % to total dietary Fe intake among infants and toddlers, respectively. Poor nutritional status and inadequate feeding practices in this study population reinforce the importance of exclusive breast-feeding during the first 6 months of life. Greater emphasis is required to improve the bioavailability of dietary Fe during complementary feeding practices.

  1. Progressive numbness of distal limbs for two years, unsteady gait for two months

    Directory of Open Access Journals (Sweden)

    Jun MA

    2016-11-01

    Full Text Available A 50-year-old female was admitted to our department, complaining of progressive numbness of distal limbs for two years and unsteady gait for two months. “Peripheral neuropathy” was the presumed diagnosis. She has suffered dry mouth for months. Neurological examination revealed proximal upper muscle strength was normal and distal was 5-/5 while muscle strength in lower limbs was normal. Tendon reflexes in all limbs were reduced, and superficial sensation as well as deep sensation in all limbs was also diminished. Deep sensation below T8-10 was diminished. Romberg’s test was positive with negative pathological reflex. Several sensory nerves action potentials (SNAPs were diminished or absent with normal compound muscle action potentials (CMAPs. Cervical MRI showed hyperintensities in the dorsal column. Serum anti-Ro/SSA antibody was positive. Tear break-up time was abnormal in either eye (5s, normal range>10s; the rate of saliva production declined 0.02 ml/min (> 1.50 ml/15 min; parotid gland contrast sialography was abnormal; lip biopsy was positive with focal lymphocytic sialadenitis with focus score ≥1. The patient was diagnosed as primary Sjogren's syndrome and sensory neuronopathy. She received oral prednisone in dose of 1mg/(kg·d for four weeks, then reduce the dosage with 5mg/w to 0.50mg/ (kg·d. Later she reduced the dosage with 2.5mg/per week. At the same time, she got cyclophosphamide (100mg every other day and hydroxychloroquine (0.20g twice a day. Numbness of limbs and unsteady gait were improved when the patient was discharged. Two month later, during the follow-up, the patient’ gait was slightly improved, but the numbness still existed. DOI: 10.3969/j.issn.1672-6731.2016.11.016

  2. Maternal mental health and nutritional status of six-month-old infants

    Directory of Open Access Journals (Sweden)

    Bruna Kulik Hassan

    2016-01-01

    Full Text Available ABSTRACT OBJECTIVE To analyze if maternal mental health is associated with infant nutritional status at six month of age. METHODS A cross-sectional study with 228 six-month-old infants who used primary health care units of the city of Rio de Janeiro, Southeastern Brazil. Mean weight-for-length and mean weight-for-age were expressed in z-scores considering the 2006 World Health Organization reference curves. Maternal mental health was measured by the 12-item General Health Questionnaire. The following cutoff points were used: ≥ 3 for common mental disorders, ≥ 5 for more severe mental disorders, and ≥ 9 for depression. The statistical analysis employed adjusted linear regression models. RESULTS The prevalence of common mental disorders, more severe mental disorders and depression was 39.9%, 23.7%, and 8.3%, respectively. Children of women with more severe mental disorders had, on average, a weight-for-length 0.37 z-scores lower than children of women without this health harm (p = 0.026. We also observed that the weight-for-length indicator of children of depressed mothers was, on average, 0.67 z-scores lower than that of children of nondepressed women (p = 0.010. Maternal depression was associated with lower mean values of weight-for-age z-scores (p = 0.041. CONCLUSIONS Maternal mental health is positively related to the inadequacy of the nutritional status of infants at six months.

  3. The status of Thailand Y2K Progress

    International Nuclear Information System (INIS)

    Srisanan, V.; Junlanan, M.; Malaivongs, K.

    1999-01-01

    This report divided into two parts deals with the general status of Y2K issues in Thailand and its effects in nuclear safeguards and physical protection and control of nuclear materials. It includes a description of safeguards in Thailand, Y2K action plan, contingency (emergency) plan, Thailand Y2K status report and the Thailand answer sheet about safeguards Y2K problem

  4. Motor development in 9-month-old infants in relation to cultural differences and iron status.

    Science.gov (United States)

    Angulo-Barroso, Rosa M; Schapiro, Lauren; Liang, Weilang; Rodrigues, Onike; Shafir, Tal; Kaciroti, Niko; Jacobson, Sandra W; Lozoff, Betsy

    2011-03-01

    Motor development, which allows infants to explore their environment, promoting cognitive, social, and perceptual development, can be influenced by cultural practices and nutritional factors, such as iron deficiency. This study compared fine and gross motor development in 209 9-month-old infants from urban areas of China, Ghana, and USA (African-Americans) and considered effects of iron status. Iron deficiency anemia was most common in the Ghana sample (55%) followed by USA and China samples. Controlling for iron status, Ghanaian infants displayed precocity in gross motor development and most fine-motor reach-and-grasp tasks. US African-Americans performed the poorest in all tasks except bimanual coordination and the large ball. Controlling for cultural site, iron status showed linear trends for gross motor milestones and fine motor skills with small objects. Our findings add to the sparse literature on infant fine motor development across cultures. The results also indicate the need to consider nutritional factors when examining cultural differences in infant development. Copyright © 2010 Wiley Periodicals, Inc.

  5. Effects of Nutritional Status on 6-Month Outcome of Hip Fractures in Elderly Patients.

    Science.gov (United States)

    Miu, Ka Ying Doris; Lam, Pui Shan

    2017-12-01

    To identify the prevalence of malnutrition in elderly hip fracture and to investigate the relationship between hip fracture patients and malnutrition on functional recovery and mortality. All hip fracture patients age >65 years admitted to a rehabilitation unit were recruited from July 2015 to June 2016. Nutritional status was assessed by Mini-Nutritional Assessment Short-Form (MNA-SF) within 72 hours of admission. Patients were reassessed at 6 months for functional status and place of residence. Length of hospital stay, in-patient mortality rate, and 6-month mortality rate were also recorded. There were 218 patients recruited. The mean age was 83.5±7.5 years. According the MNA-SF, 46 (21.1%) were well nourished, 115 (52.6%) were at risk of malnutrition, and 57 (26.1%) were malnourished. Malnourished individuals were significantly older, had lower Mini-Mental State Examination score and albumin level, were functionally more dependent and were more likely to reside in elderly care facility. A higher proportion of elderly care residents were at-risk or were malnourished on admission, discharge and at 6 months. Functional recovery was slower in the malnourished group. In-patient mortality was higher in malnourished individuals compared to those at risk of malnourishment and well-nourished individuals. The prevalence of malnutrition is high and is associated with poor functional recovery and elderly care placement. Residents of elderly care facilities are especially at risk due a higher prevalence of malnourishment. Health authorities are encouraged to evaluate the dietetic component in elderly care facilities and initiate nutrition supplementation in their planning of healthcare resources.

  6. Present status and expected progress in radiation processing dosimetry

    DEFF Research Database (Denmark)

    Kovács, A.; Miller, A.

    2004-01-01

    The paper describes the present status of radiation processing dosimetry including the methods used most widely in gamma- and electron processing as well as the new methods under development or introduction. The recent trends with respect to calibrationof routine dosimetry systems as well...

  7. Savannah River Plant Works Technical Department monthly progress report for May 1958: Deleted Version

    Energy Technology Data Exchange (ETDEWEB)

    1958-06-17

    This progress report by the Atomic Energy Division of the Savannah River Plant covers: Reactor Technology; Separation Technology; Engineering Assistance; Health Physics; and General Laboratory Work. (JT)

  8. Wills Plasma Physics Department thirty sixth 6-monthly progress report, July 1 to December 31, 1978

    International Nuclear Information System (INIS)

    1979-01-01

    Progress is reported on research programs which are proceeding in the following ares: plasma sources, hydromagnetic shock waves, rotating plasmas, magnetohydrodynamics, laser diagnostics and far infrared interferometry

  9. Wills plasma physics department thirty fifth 6-monthly progress report, Jan 1 to Jun 30, 1978

    International Nuclear Information System (INIS)

    1978-07-01

    Progress is reported on research programs which are proceeding in the following areas: plasma sources, hydromagnetic shock waves, rotating plasmas, magnetohydrodyamics, laser diagnostics, and far infrared interferometry

  10. Wills Plasma Physics Department thirty seventh 6-monthly progress report, January 1 to June 30, 1979

    International Nuclear Information System (INIS)

    1979-07-01

    Progress is reported on research programs which are proceeding in the following areas: plasma sources, hydromagnetic shock waves, magnetohydrodynamics, laser diagnostics and far infrared interferometry

  11. Predictors of changes in health status between and within patients 12 months post left ventricular assist device implantation

    DEFF Research Database (Denmark)

    Brouwers, Corline; de Jonge, Nicolaas; Caliskan, Kadir

    2014-01-01

    improvements in health status between baseline and 3 months follow-up as assessed by the KCCQ (clinical summary score: F = 33.49, P physical component score: F = 31.59, P ... 3 months and 12 months follow-up (P > 0.05 for all). Higher scores on anxiety and depression over time, older age, lower ejection fraction, and more co-morbidity were associated with poorer health status scores on one or both of the KCCQ and SF-12 subscales. The majority of the between......BACKGROUND: Improving patient-reported outcomes (e.g. health status) has become an important goal in left ventricular assist device (LVAD) therapy, in addition to reducing mortality and morbidity. We examined predictors of changes in health status scores between and within patients 12 months post...

  12. A survey of nutritional status of children 0-12 months in specialist hospital Gombe, Nigeria

    Directory of Open Access Journals (Sweden)

    Mela Danjin

    2015-01-01

    Full Text Available Background: This study was a cross-sectional survey of children and their mothers in specialist Hospital Gombe, Nigeria. Objective: Anthropometric assessment of nutritional status of the children (0-12 months and a survey of mothers′ opinion on malnutrition. Population: Children and mothers attending immunization sessions in specialist hospital Gombe, Nigeria. Materials and Methods: Hundred children (0-12 months attending immunization sessions were purposefully sampled and measured using sensitive anthropometric tools and techniques, while on the other arm of the study structured interviews were administered on the children′s consenting mothers (100 who turned in for their wards′ immunization. Only 97 out of 100 data collected on the children were used. Anthropometric indices used were height-for-age, weight-for-height, weight-for-age, and mid-upper arm circumference. Results: The study revealed a higher prevalence of moderate stunting in male (46.9% than in female (33.3% children (P 11 exhibited both severe and moderate forms of underweight. Among infants 3-5 months, moderate wasting was found to be less prevalent (4.2%. And despite the fact that 90% of their mothers showed a positive attitude toward exclusive breastfeeding, only 44% of them breastfed their infants exclusively from birth to the 6 th month of life. Conclusion: In order to address the various forms of nutritional derangements detected among the children, mothers should be targeted for infant nutritional education and authorities should institute poverty alleviation measures so as to address underlying causes of malnutrition.

  13. The U.S. RERTR program status and progress

    International Nuclear Information System (INIS)

    Travelli, A.

    1998-01-01

    The progress of the Reduced Enrichment Research and Test Reactor (RERTR) Program since its inception in 1978 is described. A brief summary of the results which the RERTR Program had achieved by the end of 1996 in collaboration with its many international partners is followed by a detailed review of the major events, findings, and activities of 1997. Significant progress has been made during the past year. In the area of U.S. acceptance of spent fuel from foreign research reactors, several shipments have taken place and additional are being planned. Intense fuel development activities are in progress, including procurement of equipment, screening of candidate materials, and production of microplates. Irradiation of the first series of microplates began in August 1997 in the Advanced Test Reactor, in Idaho. Progress has been made in the Russian RERTR program, which aims to develop and demonstrate within five years the technical means needed to convert Russian-supplied research reactors to LEU fuels. The study of an alternative LEU core for the FRM-II design has been extended to address, with favorable results, controversial performance issues which were raised at last year's meeting. Progress was also made on several aspects of producing molybdenum-99 from fission targets utilizing LEU instead of HEU. Various types of targets and processes are being pursued, with FDA approval of an LEU process projected to occur within two years. The feasibility of LEU Fuel conversion for three important DOE research reactors (BMRR, HFBR, and HFIR) has been evaluated by the RERTR program. In spite of the many momentous events which have occurred during the intervening years, and the excellent progress achieved, the most important challenges that the RERTR program faces today are not very different in type from those that were faced during the first RERTR meeting. Now, as then, the most important task is to develop new LEU fuels satisfying requirements which cannot be satisfied by any

  14. The U.S. RERTR Program. Status and progress

    International Nuclear Information System (INIS)

    Travelli, A.

    1997-01-01

    The progress of the Reduced Enrichment Research and Test Reactor (RERTR) Program since its inception in 1978 is described. A brief summary of the results which the RERTR Program had achieved by the end of 1996 in collaboration with its many international partners is followed by a detailed review of the major events, findings, and activities of 1997. Significant progress has been made during the past year. In the area of U.S. acceptance of spent fuel from foreign research reactors, several shipments have taken place and additional are being planned. Intense fuel development activities are in progress, including procurement of equipment, screening of candidate materials, and production of microplates. Irradiation of the first series of microplates began in August 1997 in the Advanced Test Reactor, in Idaho. Progress has been made in the Russian RERTR program, which aims to develop and demonstrate within five years the technical means needed to convert Russian-supplied research reactors to LEU fuels. The study of an alternative LEU core for the FRM-II design has been extended to address, with favorable results, controversial performance issues which were raised at last year's meeting. Progress was also made on several aspects of producing molybdenum-99 from fission targets utilizing LEU instead of HEU. Various types of targets and processes are being pursued, with FDA approval of an LEU process projected to occur within two years. The feasibility of LEU fuel conversion for three important DOE research reactors (BMRR, HFBR, and HFIR) has been evaluated by the RERTR program. In spite of the many momentous events which have occurred during the intervening years, and the excellent progress achieved, the most important challenges that the RERTR program faces today are not very different in type from those that were faced during the first RERTR meeting. Now, as then, the most important task is to develop new LEU fuels satisfying requirements which cannot be satisfied by any

  15. Nondiabetic Glucometabolic Status and Progression of Aortic Stiffness

    DEFF Research Database (Denmark)

    McEniery, Carmel M; Wilkinson, Ian B; Johansen, Nanna B

    2017-01-01

    -up. At baseline, cfPWV was associated with fasting and 2-h postload glucose, HbA1c, and HOMA-insulin resistance (HOMA-IR). HbA1c and HOMA-IR were associated with progression of cfPWV after adjusting for physiological confounders and cardiovascular risk factors. A 1 SD higher HbA1c and HOMA-IR were associated...... with greater increases in cfPWV (0.11 m/s per 5 years [95% CI 0.04, 0.18], P = 0.003 and 0.09 m/s per 5 years [0.01, 0.17], P = 0.03, respectively). Additional adjustment for BMI weakened the association with HOMA-IR but not with HbA1c. CONCLUSIONS HbA1c is independently associated with accelerated progression...

  16. Monte Carlos of the new generation: status and progress

    International Nuclear Information System (INIS)

    Frixione, Stefano

    2005-01-01

    Standard parton shower monte carlos are designed to give reliable descriptions of low-pT physics. In the very high-energy regime of modern colliders, this is may lead to largely incorrect predictions of the basic reaction processes. This motivated the recent theoretical efforts aimed at improving monte carlos through the inclusion of matrix elements computed beyond the leading order in QCD. I briefly review the progress made, and discuss bottom production at the Tevatron

  17. Savannah River Plant, Works Technical Department monthly progress report for March 1956

    International Nuclear Information System (INIS)

    1956-01-01

    This document details activities of the Works Technical Department during the month of March 1956. It covers reactor technology, separations technology, engineering assistance and heavy water technology

  18. Progress and status of neutron radiography and gauging in Europe

    International Nuclear Information System (INIS)

    Balasko, Marton

    1996-01-01

    European neutron radiography (NR) stations, applications and main trends of progress are surveyed. NR laboratories installed at research reactors operating in eight countries. DIANE transportable neutron source has been constructed within the framework of EURECA project. High resolution film techniques and video imaging are used in various applications. In several cases NR is combined with other non-destructive methods. The European Neutron Radiography Working Group organizes annual meetings and international projects (COST, INCO Copernicus) to promote personal contacts and scientific cooperation in this field. (author)

  19. The status of women in academic anesthesiology: a progress report.

    Science.gov (United States)

    Wong, Cynthia A; Stock, Marie Christine

    2008-07-01

    The number of women in medicine has increased steadily in the last half century. In this study, we reassessed the status of women in academic anesthesiology departments in the United States in 2006. Medical student, resident, and faculty rank gender data were obtained from the Association of American Medical Colleges. Data regarding the make-up and gender of anesthesia subspecialty society leadership, the editorial boards of Anesthesia & Analgesia and Anesthesiology, the awardees of anesthesia research grants, American Board of Anesthesiology examiners, and department chairs were obtained from websites, organization management personnel, and the Wood Library-Museum of Anesthesiology. Anesthesiology data were compared with composite data from medical school departments in other clinical specialties and to data from previous years, beginning in 1985. The percentage of medical school graduates, anesthesiology residents, and anesthesiology faculty members who are women has increased since 1985; however, the rate of increase in the percentage of women is significantly faster for medical school graduates compared with anesthesiology residents (P research grants awarded to women has not changed over several decades. The status of women in academic anesthesiology in the first decade of the millennium has, by some measures, advanced compared with 20 yr ago. However, by other measures, there has been no change. The task ahead is to identify factors that discourage qualified women medical students, residents, and junior faculty members from pursuing careers in academic anesthesiology and advancing in academic rank.

  20. The Ignition Physics Campaign on NIF: Status and Progress

    International Nuclear Information System (INIS)

    Edwards, M. J.

    2016-01-01

    We have made significant progress in ICF implosion performance on NIF since the 2011 IFSA. Employing a 3-shock, high adiabat CH (“High-Foot”) design, total neutron yields have increased 10-fold to 6.3 x10 15 (a yield of ∼ 17 kJ, which is greater than the energy invested in the DT fuel ∼ 12kJ). At that level, the yield from alpha self-heating is essentially equivalent to the compression yield, indicating that we are close to the alpha self-heating regime. Low adiabat, 4-shock High Density Carbon (HDC) capsules have been imploded in conventional gas-filled hohlraums, and employing a 6 ns, 2-shock pulse, HDC capsules were imploded in near-vacuum hohlraums with overall coupling ∼ 98%. Both the 4- and 2-shock HDC capsules had very low mix and high yield over simulated performance. Rugby holraums have demonstrated uniform x-ray drive with minimal Cross Beam Energy Transfer (CBET), and we have made good progress in measuring and modelling growth of ablation front hydro instabilities. (paper)

  1. Current status and progress of pancreatic cancer in China.

    Science.gov (United States)

    Lin, Quan-Jun; Yang, Feng; Jin, Chen; Fu, De-Liang

    2015-07-14

    Cancer is currently one of the most important public health problems in the world. Pancreatic cancer is a fatal disease with poor prognosis. As in most other countries, the health burden of pancreatic cancer in China is increasing, with annual mortality rates almost equal to incidence rates. The increasing trend of pancreatic cancer incidence is more significant in the rural areas than in the urban areas. Annual diagnoses and deaths of pancreatic cancer in China are now beyond the number of cases in the United States. GLOBOCAN 2012 estimates that cases in China account for 19.45% (65727/337872) of all newly diagnosed pancreatic cancer and 19.27% (63662/330391) of all deaths from pancreatic cancer worldwide. The population's growing socioeconomic status contributes to the rapid increase of China's proportional contribution to global rates. Here, we present an overview of control programs for pancreatic cancer in China focusing on prevention, early diagnosis and treatment. In addition, we describe key epidemiological, demographic, and socioeconomic differences between China and developed countries. Facts including no nationwide screening program for pancreatic cancer, delay in early detection resulting in a late stage at presentation, lack of awareness of pancreatic cancer in the Chinese population, and low investment compared with other cancer types by government have led to backwardness in China's pancreatic cancer diagnosis and treatment. Finally, we suggest measures to improve health outcomes of pancreatic cancer patients in China.

  2. Cerebral ultrasound in newborns with severs asphyxia: correlation with the neurological status at 12 months

    International Nuclear Information System (INIS)

    Esparza, J.; Gonzalez, A.; Inchusta, M.I.; Pina, L.

    1997-01-01

    To establish the prognostic value of cerebral ultrasound performed in newborns (NB) with severe asphyxia. A retrospective study of the ultrasound (US) findings during the acute phase of severe perinatal asphyxia was carried out in a series of 182 NB. The US images were correlated with the neurological status of the infants at the age of 12 months. Of the 122 NB with normal US findings, 94,2% presented no sequelae or a slightly impaired psychomotor performance attributable to prematurity, thus conferring a high prognostic value to this technique. Subependymal cerebral hemorrhage was diagnosed in 35 cases (22 grades I and II, 9 grade III and 4 grade IV), in whom the prognosis was related to the grade of hemorrhage. Twenty-five NB were diagnosed as having some type of hypoxic or ischemic encephalopathy, eith the prognosis differing according to the topography of the lesion and the reversibility of the ultrasonographic signs: poor prognosis in ten NB with diffuse cerebral involvement and in four with periventricular leukomalacia, uncertain prognosis in seven NB with focal brain damage and a good prognosis in four with reversible cerebral edema. (Author) 35 refs

  3. HIFS VNL Monthly Progress Report Preparation for NDCX-II Project

    International Nuclear Information System (INIS)

    Logan, Grant; Kwan, Joe; Barnard, John; Friedman, Alex; Gilson, Erik; Leitner, Matthaeus; Waldron, Will; Bieniosek, Frank

    2009-01-01

    In preparation for the project and for anticipated review in August, the HIFS-VNL hosted an NDCX-II Advisory Meeting at LBNL on May 27, 2009. A number of experts in accelerator physics, engineering, and construction were asked to visit for a full day, listen to presentations on the project, its goals, and its status, and to offer their advice on how best to proceed, what topics needed attention, and what technical options seemed most attractive to them. This was a productive meeting, and the Committee's comments will provide useful guidance.

  4. HTGR accident initiation and progression analysis status report. Volume VIII. Responses to comments on AIPA status report

    Energy Technology Data Exchange (ETDEWEB)

    Raabe, P.H.

    1977-01-01

    The first seven volumes of the report series provide formal documentation of the status of the ERDA-sponsored Accident Initiation and Progression Analysis (AIPA) study as of the end of FY75. That portion of the report was given broad distribution to government agencies, industrial organizations, and academic institutions. Comments on the Status Report have been actively solicited from these and other organizations. The volume presented (the eighth in the AIPA Status Report) documents all of the formal written comments that have been received as of September 30, 1976, together with the responses to those comments. The comments as presented are direct quotations from the manuscripts as submitted by the reviewers; none have been paraphrased. The comments are presented in the same order as submitted by the reviewers and are generally addressed individually.

  5. HTGR accident initiation and progression analysis status report. Volume VIII. Responses to comments on AIPA status report

    International Nuclear Information System (INIS)

    Raabe, P.H.

    1977-01-01

    The first seven volumes of the report series provide formal documentation of the status of the ERDA-sponsored Accident Initiation and Progression Analysis (AIPA) study as of the end of FY75. That portion of the report was given broad distribution to government agencies, industrial organizations, and academic institutions. Comments on the Status Report have been actively solicited from these and other organizations. The volume presented (the eighth in the AIPA Status Report) documents all of the formal written comments that have been received as of September 30, 1976, together with the responses to those comments. The comments as presented are direct quotations from the manuscripts as submitted by the reviewers; none have been paraphrased. The comments are presented in the same order as submitted by the reviewers and are generally addressed individually

  6. User Interfaces for Patient-Centered Communication of Health Status and Care Progress

    Science.gov (United States)

    Wilcox-Patterson, Lauren

    2013-01-01

    The recent trend toward patients participating in their own healthcare has opened up numerous opportunities for computing research. This dissertation focuses on how technology can foster this participation, through user interfaces to effectively communicate personal health status and care progress to hospital patients. I first characterize the…

  7. Progress and status of the Integral Fast Reactor (IFR) fuel cycle development

    International Nuclear Information System (INIS)

    Till, C.E.; Chang, Y.I.

    1993-01-01

    The Integral Fast Reactor (IFR) fuel cycle holds promise for substantial improvements in economics, diversion-resistance, and waste management. This paper discusses technical features of the IFR fuel cycle, its technical progress, the development status, and the future plans and directions

  8. Progress and status of the Integral Fast Reactor (IFR) fuel cycle development

    International Nuclear Information System (INIS)

    Till, C.E.; Chang, Y.I.

    1991-01-01

    The Integral Fast Reactor (IFR) fuel cycle holds promise for substantial improvements in economics, diversion-resistance, and waste management. This paper discusses technical features of the IFR fuel cycle, its technical progress, the development status, and the future plans and directions. 10 refs

  9. 78 FR 46947 - Adequacy Status of the Houston-Galveston-Brazoria, Texas Reasonable Further Progress and...

    Science.gov (United States)

    2013-08-02

    ... ENVIRONMENTAL PROTECTION AGENCY [FRL-9841-2] Adequacy Status of the Houston-Galveston-Brazoria... has found that the motor vehicle emissions budgets (MVEBs) in the Houston-Galveston-Brazoria, Texas... 2: Table 1-- Houston-Galveston-Brazoria 1997 8-Hour Ozone Reasonable Further Progress NOX and VOC...

  10. 76 FR 4342 - Adequacy Status of the Houston-Galveston-Brazoria, Texas Reasonable Further Progress and...

    Science.gov (United States)

    2011-01-25

    ... ENVIRONMENTAL PROTECTION AGENCY [FRL-9256-8] Adequacy Status of the Houston-Galveston-Brazoria... vehicle emissions budgets (MVEBs) in the Houston-Galveston-Brazoria, Texas (HGB) Reasonable Further... Progress (RFP) SIP and an Attainment Demonstration SIP for the Houston- Galveston-Brazoria (HGB) ozone...

  11. Mental Status as a Predictor of Daily Function in Progressive Dementia.

    Science.gov (United States)

    Reed, Bruce R.; And Others

    1989-01-01

    Compared Mini Mental Status Exam (MMSE) scores and activities of daily living (ADL) scores from 59 patients with progressive dementias. MMSE scores explained approximately one-third of variance in both instrumental and physical ADLs. Findings suggest that cognitive losses and functional impairments are 2 distinct aspects of dementia severity which…

  12. Progress and status of the Integral Fast Reactor (IFR) fuel cycle development

    International Nuclear Information System (INIS)

    Till, C.E.; Chang, Y.I.

    1991-01-01

    The Integral Fast Reactor (IFR) fuel cycle holds promise for substantial improvements in economics, diversion-resistance, and waste management. This paper discusses technical features of the IFR fuel cycle, its technical progress, the development status, and the future plans and directions. (author)

  13. Progress and status of the Integral Fast Reactor (IFR) fuel cycle development

    Energy Technology Data Exchange (ETDEWEB)

    Till, C.E.; Chang, Y.I.

    1991-01-01

    The Integral Fast Reactor (IFR) fuel cycle holds promise for substantial improvements in economics, diversion-resistance, and waste management. This paper discusses technical features of the IFR fuel cycle, its technical progress, the development status, and the future plans and directions. 10 refs.

  14. Progress and status of the Integral Fast Reactor (IFR) fuel cycle development

    Energy Technology Data Exchange (ETDEWEB)

    Till, C.E.; Chang, Y.I.

    1993-03-01

    The Integral Fast Reactor (IFR) fuel cycle holds promise for substantial improvements in economics, diversion-resistance, and waste management. This paper discusses technical features of the IFR fuel cycle, its technical progress, the development status, and the future plans and directions.

  15. Progress and status of the Integral Fast Reactor (IFR) fuel cycle development

    Energy Technology Data Exchange (ETDEWEB)

    Till, C.E.; Chang, Y.I.

    1993-01-01

    The Integral Fast Reactor (IFR) fuel cycle holds promise for substantial improvements in economics, diversion-resistance, and waste management. This paper discusses technical features of the IFR fuel cycle, its technical progress, the development status, and the future plans and directions.

  16. Effects of a 5-month football program on perceived psychological status and body composition of overweight boys

    DEFF Research Database (Denmark)

    Seabra, A C; Seabra, A F; Brito, J

    2014-01-01

    The effects of a 5-month intervention of football instruction and practice on the perceived psychological status and body composition of overweight boys were examined. Twelve boys (8-12 years; body mass index ≥ 85th percentile) participated in a structured 5-month football program, consisting...... of four weekly 60-90 min sessions with mean heart rate > 80%HRmax [football group (FG)]. A control group (CG) included eight boys of equivalent age from an obesity clinic located in the same area as the school. Both groups participated in two sessions of 45-90-min physical education per week at school....... Indicators of perceived psychological status included body image, self-esteem, attraction to participation in physical activity, and perceived physical competence measured with standardized questionnaires. Body composition was evaluated using dual-energy X-ray absorptiometry. From baseline through 5 months...

  17. Association of weight change with progression of meniscal intrasubstance degeneration over 48 months. Data from the Osteoarthritis Initiative

    Energy Technology Data Exchange (ETDEWEB)

    Brandao Guimaraes, Julio [University of California, Musculoskeletal and Quantitative Imaging Research Group (MQIR), Department of Radiology and Biomedical Imaging, San Francisco, CA (United States); Federal University of Sao Paulo (UNIFESP), Department of Radiology, Sao Paulo (Brazil); DASA Laboratory, Department of Radiology, Sao Paulo (Brazil); Nevitt, Michael C.; McCulloch, Charles E.; Liu, Felix [University of California, Department of Epidemiology and Biostatistics, San Francisco, CA (United States); Schwaiger, Benedikt J.; Gersing, Alexandra S.; Facchetti, Luca; Bucknor, Matthew D.; Chanchek, Nattagan; Joseph, Gabby B.; Link, Thomas M. [University of California, Musculoskeletal and Quantitative Imaging Research Group (MQIR), Department of Radiology and Biomedical Imaging, San Francisco, CA (United States)

    2018-03-15

    To investigate the association of weight change over 48 months with progression of meniscal intrasubstance degeneration (MID). We studied 487 subjects with MID at baseline and after 48 months using 3-T MRI with the same protocol (FSE sequences with and without fat suppression). These participants lost weight (≥3%, n = 141), had moderate weight gain (3-10%, n = 77), substantial weight gain (>10%, n = 15) or maintained stable weight (n = 254). Progression of MID to a meniscal tear was assessed using the WORMS grading system and compared among weight change groups using logistic regression. ANOVA and chi-square tests were used to study the differences in subjects' characteristics. Progression of MID increased from weight loss to substantial weight gain (p < 0.001) and was significantly more likely with both moderate weight gain (odds ratio [OR], 4.9; 95% confidence interval [CI] 2.4-8.9) and substantial weight gain (OR, 9.5; 95% CI 3.2-28.5) compared to stable weight. Results were similar in both menisci for moderate weight gain (medial: OR, 6.8; 95% CI 3.5-11.3; lateral: OR, 2.6; 95% CI 1.1-6.6) and substantial weight gain (medial: OR, 21.0; 95% CI 5.1-80.7; lateral: OR, 9.7; 95% CI 0.95-100.2). Weight gain is associated with an increased likelihood that meniscal intrasubstance degeneration will progress with the risk increasing with greater weight gain. (orig.)

  18. [National Institute for Petroleum and Energy Research] monthly progress report, July 1992

    Energy Technology Data Exchange (ETDEWEB)

    1992-09-01

    Accomplishments for the month of July are described briefly under tasks for: Energy Production Research; Fuels Research; and Supplemental Government Program. Energy Production Research includes: reservoir assessment and characterization; TORIS research support; development of improved microbial flooding methods; surfactant flooding methods; development of improved alkaline flooding methods; mobility control and sweep improvement in chemical flooding; gas flood performance prediction improvement; mobility control, profile modification, and sweep improvement in gas flooding; three-phase relative permeability research; thermal processes for light oil recovery; thermal processes for heavy oil recovery; and imaging techniques applied to the study of fluids in porous media. Fuel Research includes: development of analytical methodology for analysis of heavy crudes; and thermochemistry and thermophysical properties of organic nitrogen- and diheteroatom-containing compounds. Supplement Government Program includes: microbial-enhanced waterflooding field project; feasibility study of heavy oil recovery in the midcontinent region--Oklahoma, Kansas, and Missouri; surfactant-enhanced alkaline flooding field project; development of methods for mapping distribution of clays in petroleum reservoirs; summary of geological and production characteristics of class 1. unstructured, deltaic reservoirs; third international reservoir characterization technical conference; process-engineering property measurements on heavy petroleum components; development and application of petroleum production technologies; upgrade BPO crude oil data base; simulation analysis of steam-foam projects; analysis of the US oil resource base and estimate of future recoverable oil; DOE education initiative project; and technology transfer to independent producers.

  19. (National Institute for Petroleum and Energy Research) monthly progress report, July 1992

    Energy Technology Data Exchange (ETDEWEB)

    1992-09-01

    Accomplishments for the month of July are described briefly under tasks for: Energy Production Research; Fuels Research; and Supplemental Government Program. Energy Production Research includes: reservoir assessment and characterization; TORIS research support; development of improved microbial flooding methods; surfactant flooding methods; development of improved alkaline flooding methods; mobility control and sweep improvement in chemical flooding; gas flood performance prediction improvement; mobility control, profile modification, and sweep improvement in gas flooding; three-phase relative permeability research; thermal processes for light oil recovery; thermal processes for heavy oil recovery; and imaging techniques applied to the study of fluids in porous media. Fuel Research includes: development of analytical methodology for analysis of heavy crudes; and thermochemistry and thermophysical properties of organic nitrogen- and diheteroatom-containing compounds. Supplement Government Program includes: microbial-enhanced waterflooding field project; feasibility study of heavy oil recovery in the midcontinent region--Oklahoma, Kansas, and Missouri; surfactant-enhanced alkaline flooding field project; development of methods for mapping distribution of clays in petroleum reservoirs; summary of geological and production characteristics of class 1. unstructured, deltaic reservoirs; third international reservoir characterization technical conference; process-engineering property measurements on heavy petroleum components; development and application of petroleum production technologies; upgrade BPO crude oil data base; simulation analysis of steam-foam projects; analysis of the US oil resource base and estimate of future recoverable oil; DOE education initiative project; and technology transfer to independent producers.

  20. The progression of heartworm associated respiratory disease (HARD) in SPF cats 18 months after Dirofilaria immitis infection.

    Science.gov (United States)

    Dillon, A Ray; Blagburn, Bryon L; Tillson, Michael; Brawner, William; Welles, Betsy; Johnson, Calvin; Cattley, Russell; Rynders, Pat; Barney, Sharron

    2017-11-09

    Heartworm-associated respiratory disease (HARD) in cats is induced by the arrival and death of immature adult Dirofilaria immitis in the pulmonary system and is indistinguishable from mature adult heartworm infection. A controlled, blind research study investigated the long-term (18 months post infection, PI) consequences of the inflammatory response associated with the death of immature adult heartworms in cats. Three groups of cats, 10 per group, were infected with 100 third-stage (L3) larvae by subcutaneous injection. Group A cats were treated with selamectin (Revolution®; Zoetis) per label directions at 28 days PI and once monthly for 17 months. Group B cats were treated orally with ivermectin (Ivomec®; Merial) at 150 μg/kg) at 70 days PI, then every 2 weeks for 15 months. Group C cats were untreated PI. At baseline (Day 0) and on Days 70, 110, 168, 240, 309, 380, and 505 PI, peripheral blood, serum, bronchial lavage, and thoracic radiographic images were collected. The selamectin-treated cats (Group A) and ivermectin-treated cats (Group B) were free of heartworms or heartworm fragments at necropsy. All cats became heartworm antibody positive at some time point in the study except for one cat in Group A. Only cats in Group C (all with adult heartworms) were heartworm antigen positive. The heartworm antibody titer for Group B was highest on Days 110 to 168 and then decreased over time and 50% were serologically antibody negative on Day 240. Eosinophilic bronchoalveolar lavage (BAL) cytology and peripheral eosinophilia were most pronounced on Day 110 in all cats. Randomly distributed myofibrocytes in the lungs of some Group A cats suggest that precardiac larval stages were affecting the lungs. Radiographs in Group B cats demonstrated partial resolution of the initial HARD reaction but chronic myofibrocyte proliferation was histologically evident 18 months after infection. HARD was induced by immature adult worm infection with progressive improvement

  1. Cle Elum and Supplementation Research Facility : Monthly Progress Report October 2008.

    Energy Technology Data Exchange (ETDEWEB)

    Cle Elum Supplementation and Research Facility

    2008-12-11

    FISH PRODUCTION: On October 7th the 2008 spawning season was completed. 823 adults were transferred to the facility for the 2008 season. The overall adult mortality was 6.9% (1.3% pre-spawning mortality and 5.6% encountered after sorting). Wild/natural salmon collected included 278 females, 173 males, and 29 jacks for a total 480 fish for the 2008 brood. Supplemented brood stock collected included 149 adults (85 females, 35 males and 29 jacks). Hatchery control brood collected for research included 194 adults (91 females, 68 males and 35 jacks). Eggs will be inventoried in November with an actual summary of eggs numbers to be submitted for the November report. The estimated egg takes (production) for the 2008 season was 1,375,146 eggs with 1,006,063 comprising of W x W crosses and 250,755 eggs of H x H crosses with 118,328 supplement crosses. Total fish on hand for the 2007 brood is 768,751 with an average fish per pound of 30.6 f/lb. FISH CULTURE: The marking and pit-tagging operation started on October 13th. The pit-tagging portion was completed on October 23rd. A total 40,000 juveniles were pit-tagged (2,000 from each of the production ponds and 4,000 each for the hatchery juvenile ponds 9 & 10). Cle Elum staff began shocking, sorting, counting and splitting eggs in incubation. Shocking eggs will separate live eggs from dead eggs. Eggs are treated with formalin three times a week to control fungus. The focus for the culturists during the month of October entail completing the final spawn (egg take) on the 7th, pond cleaning, keeping the marking trailers supplied with fish and end of month sampling. The adult holding ponds were power washed and winterized for the shut down period. Facility crew members Greg Strom and Mike Whitefoot assisted Joe Blodgett and his crew with fish brood collection on the 22nd of October. Fall Chinook and Coho salmon were seined up and put in tanker trucks from Chandler canal and transported to holding ponds for later spawning. Charlie

  2. The development and utility of a novel scale that quantifies the glycemic progression toward type 1 diabetes over 6 months.

    Science.gov (United States)

    Sosenko, Jay M; Skyler, Jay S; Beam, Craig A; Boulware, David; Mahon, Jeffrey L; Krischer, Jeffrey P; Greenbaum, Carla J; Rafkin, Lisa E; Matheson, Della; Herold, Kevan C; Palmer, Jerry P

    2015-05-01

    We developed a scale to serve as a potential end point for 6-month glycemic progression (PS6M) toward type 1 diabetes (T1D) in autoantibody-positive relatives of individuals with T1D. The PS6M was developed from Diabetes Prevention Trial-Type 1 (DPT-1) data and tested in the TrialNet Pathway to Prevention Study (PTP). It is the difference between 6-month glucose sum values (30-120 min oral glucose tolerance test values) and values predicted for nonprogressors. The PS6M predicted T1D in the PTP (P 7.00 (P < 0.001 for all). The PS6M is an indicator of short-term glycemic progression to T1D that could be a useful tool for assessing preventive treatments and biomarkers. © 2015 by the American Diabetes Association. Readers may use this article as long as the work is properly cited, the use is educational and not for profit, and the work is not altered.

  3. MRI Characterizes the Progressive Course of AD and Predicts Conversion to Alzheimer’s Dementia 24 Months Before Probable Diagnosis

    Directory of Open Access Journals (Sweden)

    Christian Salvatore

    2018-05-01

    Full Text Available There is no disease-modifying treatment currently available for AD, one of the more impacting neurodegenerative diseases affecting more than 47.5 million people worldwide. The definition of new approaches for the design of proper clinical trials is highly demanded in order to achieve non-confounding results and assess more effective treatment. In this study, a cohort of 200 subjects was obtained from the Alzheimer’s Disease Neuroimaging Initiative. Subjects were followed-up for 24 months, and classified as AD (50, progressive-MCI to AD (50, stable-MCI (50, and cognitively normal (50. Structural T1-weighted MRI brain studies and neuropsychological measures of these subjects were used to train and optimize an artificial-intelligence classifier to distinguish mild-AD patients who need treatment (AD + pMCI from subjects who do not need treatment (sMCI + CN. The classifier was able to distinguish between the two groups 24 months before AD definite diagnosis using a combination of MRI brain studies and specific neuropsychological measures, with 85% accuracy, 83% sensitivity, and 87% specificity. The combined-approach model outperformed the classification using MRI data alone (72% classification accuracy, 69% sensitivity, and 75% specificity. The patterns of morphological abnormalities localized in the temporal pole and medial-temporal cortex might be considered as biomarkers of clinical progression and evolution. These regions can be already observed 24 months before AD definite diagnosis. The best neuropsychological predictors mainly included measures of functional abilities, memory and learning, working memory, language, visuoconstructional reasoning, and complex attention, with a particular focus on some of the sub-scores of the FAQ and AVLT tests.

  4. β2 -microglobulin normalization within 6 months of ibrutinib-based treatment is associated with superior progression-free survival in patients with chronic lymphocytic leukemia.

    Science.gov (United States)

    Thompson, Philip A; O'Brien, Susan M; Xiao, Lianchun; Wang, Xuemei; Burger, Jan A; Jain, Nitin; Ferrajoli, Alessandra; Estrov, Zeev; Keating, Michael J; Wierda, William G

    2016-02-15

    A high pretreatment β2 -microglobulin (B2M) level is associated with inferior survival outcomes in patients with chronic lymphocytic leukemia. However, to the authors' knowledge, the prognostic and predictive significance of changes in B2M during treatment have not been reported to date. The authors analyzed 83 patients treated with ibrutinib-based regimens (66 with recurrent/refractory disease) and 198 treatment-naive patients who were treated with combined fludarabine, cyclophosphamide, and rituximab (FCR) to characterize changes in B2M and their relationship with clinical outcomes. B2M rapidly decreased during treatment with ibrutinib; on multivariable analysis, patients who received FCR (odds ratio, 0.40; 95% confidence interval [95% CI], 0.18-0.90 [P = .027]) were less likely to have normalized B2M at 6 months than patients treated with ibrutinib. On univariable analysis, normalization of B2M was associated with superior progression-free survival (PFS) from the 6-month landmark in patients treated with ibrutinib-based regimens and FCR. On multivariable analysis, failure to achieve normalized B2M at 6 months of treatment was associated with inferior PFS (hazard ratio, 16.9; 95% CI, 1.3-220.0 [P = .031]) for patients treated with ibrutinib, after adjusting for the effects of baseline B2M, stage of disease, fludarabine-refractory disease, and del(17p). In contrast, in patients treated with FCR, negative minimal residual disease status in the bone marrow was the only variable found to be significantly associated with superior PFS (hazard ratio, 0.28; 95% CI, 0.12-0.67 [P = .004]). Normalization of B2M at 6 months in patients treated with ibrutinib was found to be a useful predictor of subsequent PFS and may assist in clinical decision-making. © 2015 American Cancer Society.

  5. FERMILAB ACCELERATOR R&D PROGRAM TOWARDS INTENSITY FRONTIER ACCELERATORS : STATUS AND PROGRESS

    Energy Technology Data Exchange (ETDEWEB)

    Shiltsev, Vladimir [Fermilab

    2016-11-15

    The 2014 P5 report indicated the accelerator-based neutrino and rare decay physics research as a centrepiece of the US domestic HEP program at Fermilab. Operation, upgrade and development of the accelerators for the near- term and longer-term particle physics program at the Intensity Frontier face formidable challenges. Here we discuss key elements of the accelerator physics and technology R&D program toward future multi-MW proton accelerators and present its status and progress. INTENSITY FRONTIER ACCELERATORS

  6. Androgen receptor status is highly conserved during tumor progression of breast cancer.

    Science.gov (United States)

    Grogg, André; Trippel, Mafalda; Pfaltz, Katrin; Lädrach, Claudia; Droeser, Raoul A; Cihoric, Nikola; Salhia, Bodour; Zweifel, Martin; Tapia, Coya

    2015-11-09

    With the advent of new and more efficient anti-androgen drugs targeting androgen receptor (AR) in breast cancer (BC) is becoming an increasingly important area of investigation. This would potentially be most useful in triple negative BC (TNBC), where better therapies are still needed. The assessment of AR status is generally performed on the primary tumor even if the tumor has already metastasized. Very little is known regarding discrepancies of AR status during tumor progression. To determine the prevalence of AR positivity, with emphasis on TNBCs, and to investigate AR status during tumor progression, we evaluated a large series of primary BCs and matching metastases and recurrences. AR status was performed on 356 primary BCs, 135 matching metastases, and 12 recurrences using a next-generation Tissue Microarray (ngTMA). A commercially available AR antibody was used to determine AR-status by immunohistochemistry. AR positivity was defined as any nuclear staining in tumor cells ≥1 %. AR expression was correlated with pathological tumor features of the primary tumor. Additionally, the concordance rate of AR expression between the different tumor sites was determined. AR status was positive in: 87 % (307/353) of primary tumors, 86.1 % (105/122) of metastases, and in 66.7 % (8/12) of recurrences. TNBC tested positive in 11.4 %, (4/35) of BCs. A discrepant result was seen in 4.3 % (5/117) of primary BC and matching lymph node (LN) metastases. Three AR negative primary BCs were positive in the matching LN metastasis, representing 17.6 % of all negative BCs with lymph node metastases (3/17). Two AR positive primary BCs were negative in the matching LN metastasis, representing 2.0 % of all AR positive BCs with LN metastases (2/100). No discrepancies were seen between primary BC and distant metastases or recurrence (n = 17). Most primary (87 %) and metastasized (86.1 %) BCs are AR positive including a significant fraction of TNBCs (11.4 %). Further, AR status is

  7. Androgen receptor status is highly conserved during tumor progression of breast cancer

    International Nuclear Information System (INIS)

    Grogg, André; Trippel, Mafalda; Pfaltz, Katrin; Lädrach, Claudia; Droeser, Raoul A.; Cihoric, Nikola; Salhia, Bodour; Zweifel, Martin; Tapia, Coya

    2015-01-01

    With the advent of new and more efficient anti-androgen drugs targeting androgen receptor (AR) in breast cancer (BC) is becoming an increasingly important area of investigation. This would potentially be most useful in triple negative BC (TNBC), where better therapies are still needed. The assessment of AR status is generally performed on the primary tumor even if the tumor has already metastasized. Very little is known regarding discrepancies of AR status during tumor progression. To determine the prevalence of AR positivity, with emphasis on TNBCs, and to investigate AR status during tumor progression, we evaluated a large series of primary BCs and matching metastases and recurrences. AR status was performed on 356 primary BCs, 135 matching metastases, and 12 recurrences using a next-generation Tissue Microarray (ngTMA). A commercially available AR antibody was used to determine AR-status by immunohistochemistry. AR positivity was defined as any nuclear staining in tumor cells ≥1 %. AR expression was correlated with pathological tumor features of the primary tumor. Additionally, the concordance rate of AR expression between the different tumor sites was determined. AR status was positive in: 87 % (307/353) of primary tumors, 86.1 % (105/122) of metastases, and in 66.7 % (8/12) of recurrences. TNBC tested positive in 11.4 %, (4/35) of BCs. A discrepant result was seen in 4.3 % (5/117) of primary BC and matching lymph node (LN) metastases. Three AR negative primary BCs were positive in the matching LN metastasis, representing 17.6 % of all negative BCs with lymph node metastases (3/17). Two AR positive primary BCs were negative in the matching LN metastasis, representing 2.0 % of all AR positive BCs with LN metastases (2/100). No discrepancies were seen between primary BC and distant metastases or recurrence (n = 17). Most primary (87 %) and metastasized (86.1 %) BCs are AR positive including a significant fraction of TNBCs (11.4 %). Further, AR status is highly

  8. Health Status and Risk Factors among Adolescent Survivors One Month after the 2014 Ludian Earthquake

    Directory of Open Access Journals (Sweden)

    Bihan Tang

    2015-06-01

    Full Text Available Background: An earthquake struck Ludian in Yunnan Province (China on 3 August 2014, resulting in 3143 injuries, 617 deaths, and 112 missing persons. Our study aimed at estimating the health status and associated determinants among adolescent survivors after the Ludian earthquake. Methods: A cross-sectional survey of 845 was conducted at the Ludian No. 1 Middle School. Descriptive statistics, t-tests, ANOVA and stepwise linear regression analysis were used for data analysis. Results: The mean scores on the physical component summary (PCS and mental component summary (MCS were 46.23 (SD = 7.10 and 36.34 (SD = 7.09, respectively. Lower PCS scores in the aftermath of an earthquake were associated with being trapped or in danger, being female, being an ethnic minority, injury to self and house damage, while lower MSC scores were associated with fear during the earthquake, Han ethnicity, death in the family, not being involved in the rescue and low household income. Conclusions: In our study, significant associations between demographic, socio-economic, and trauma-related experiences variables and overall physical and mental health of adolescent survivors were presented. The results of this study help expand our knowledge of health status among adolescent survivors after the Ludian earthquake.

  9. Poor nutritional status of older subacute patients predicts clinical outcomes and mortality at 18 months of follow-up.

    Science.gov (United States)

    Charlton, K; Nichols, C; Bowden, S; Milosavljevic, M; Lambert, K; Barone, L; Mason, M; Batterham, M

    2012-11-01

    Older malnourished patients experience increased surgical complications and greater morbidity compared with their well-nourished counterparts. This study aimed to assess whether nutritional status at hospital admission predicted clinical outcomes at 18 months follow-up. A retrospective analysis of N=2076 patient admissions (65+ years) from two subacute hospitals, New South Wales, Australia. Analysis of outcomes at 18 months, according to nutritional status at index admission, was performed in a subsample of n = 476. Nutritional status was determined within 72 h of admission using the Mini Nutritional Assessment (MNA). Outcomes, obtained from electronic patient records, included hospital readmission rate, total Length of Stay (LOS), change in level of care at discharge and mortality. Survival analysis, using a Cox proportional hazards model, included age, sex, Major Disease Classification, mobility and LOS at index admission as covariates. At baseline, 30% of patients were malnourished and 53% were at risk of malnutrition. LOS was higher in malnourished and at risk, compared with well-nourished patients (median (interquartile range): 34 (21, 58); 26 (15, 41); 20 (14, 26) days, respectively; Pclinical outcomes and identifies a need to target this population for nutritional intervention following hospital discharge.

  10. Investigating the Visual-Motor Integration Skills of 60-72-Month-Old Children at High and Low Socio-Economic Status as Regard the Age Factor

    Science.gov (United States)

    Ercan, Zülfiye Gül; Ahmetoglu, Emine; Aral, Neriman

    2011-01-01

    This study aims to define whether age creates any differences in the visual-motor integration skills of 60-72 months old children at low and high socio-economic status. The study was conducted on a total of 148 children consisting of 78 children representing low socio-economic status and 70 children representing high socio-economic status in the…

  11. Iodine status and associations with feeding practices and psychomotor milestone development in six-month-old South African infants.

    Science.gov (United States)

    Osei, Jennifer; Baumgartner, Jeannine; Rothman, Marinel; Matsungo, Tonderayi M; Covic, Namukolo; Faber, Mieke; Smuts, Cornelius M

    2017-10-01

    Iodine is important for normal growth and psychomotor development. While infants below 6 months of age receive iodine from breast milk or fortified infant formula, the introduction of complementary foods poses a serious risk for deteriorating iodine status. This cross-sectional analysis assessed the iodine status of six-month-old South African infants and explored its associations with feeding practices and psychomotor milestone development. Iodine concentrations were measured in infant (n = 386) and maternal (n = 371) urine (urinary iodine concentration [UIC]), and in breast milk (n = 257 [breast milk iodine concentrations]). Feeding practices and psychomotor milestone development were assessed in all infants. The median (25th-75th percentile) UIC in infants was 345 (213-596) μg/L and was significantly lower in stunted (302 [195-504] μg/L) than non-stunted (366 [225-641] μg/L) infants. Only 6.7% of infants were deficient. Maternal UIC (128 [81-216] μg/L; r s  = 0.218, p psychomotor developmental scores were observed. Our results suggest that iodine intake in the studied six-month-old infants was adequate. Iodine in breast milk and commercial infant cereals potentially contributed to this adequate intake. © 2016 John Wiley & Sons Ltd.

  12. Community mental health status six months after the Sewol ferry disaster in Ansan, Korea

    OpenAIRE

    Hee Jung Yang; Hae Kwan Cheong; Bo Youl Choi; Min-Ho Shin; Hyeon Woo Yim; Dong-Hyun Kim; Gawon Kim; Soon Young Lee

    2015-01-01

    OBJECTIVES: The disaster of the Sewol ferry that sank at sea off Korea?s southern coast of the Yellow Sea on April 16, 2014 was a tragedy that brought grief and despair to the whole country. The aim of this study was to evaluate the mental health effects of this disaster on the community of Ansan, where most victims and survivors resided. METHODS: The self-administered questionnaire survey was conducted 4 to 6 months after the accident using the Korean Community Health Survey system, an annua...

  13. Household food (in)security and nutritional status of urban poor children aged 6 to 23 months in Kenya.

    Science.gov (United States)

    Mutisya, Maurice; Kandala, Ngianga-Bakwin; Ngware, Moses Waithanji; Kabiru, Caroline W

    2015-10-13

    Millions of people in low and low middle income countries suffer from extreme hunger and malnutrition. Research on the effect of food insecurity on child nutrition is concentrated in high income settings and has produced mixed results. Moreover, the existing evidence on food security and nutrition in children in low and middle income countries is either cross-sectional and/or is based primarily on rural populations. In this paper, we examine the effect of household food security status and its interaction with household wealth status on stunting among children aged between 6 and 23 months in resource-poor urban setting in Kenya. We use longitudinal data collected between 2006 and 2012 from two informal settlements in Nairobi, Kenya. Mothers and their new-borns were recruited into the study at birth and followed prospectively. The analytical sample comprised 6858 children from 6552 households. Household food security was measured as a latent variable derived from a set of questions capturing the main domains of access, availability and affordability. A composite measure of wealth was calculated using asset ownership and amenities. Nutritional status was measured using Height-for-Age (HFA) z-scores. Children whose HFA z-scores were below -2 standard deviation were categorized as stunted. We used Cox regression to analyse the data. The prevalence of stunting was 49 %. The risk of stunting increased by 12 % among children from food insecure households. When the joint effect of food security and wealth status was assessed, the risk of stunting increased significantly by 19 and 22 % among children from moderately food insecure and severely food insecure households and ranked in the middle poor wealth status. Among the poorest and least poor households, food security was not statistically associated with stunting. Our results shed light on the joint effect of food security and wealth status on stunting. Study findings underscore the need for social protection policies to

  14. Nutritional and developmental status among 6- to 8-month-old children in southwestern Uganda: a cross-sectional study.

    Science.gov (United States)

    Muhoozi, Grace K M; Atukunda, Prudence; Mwadime, Robert; Iversen, Per Ole; Westerberg, Ane C

    2016-01-01

    Undernutrition continues to pose challenges to Uganda's children, but there is limited knowledge on its association with physical and intellectual development. In this cross-sectional study, we assessed the nutritional status and milestone development of 6- to 8-month-old children and associated factors in two districts of southwestern Uganda. Five hundred and twelve households with mother-infant (6-8 months) pairs were randomly sampled. Data about background variables (e.g. household characteristics, poverty likelihood, and child dietary diversity scores (CDDS)) were collected using questionnaires. Bayley Scales of Infant and Toddler Development (BSID III) and Ages and Stages questionnaires (ASQ) were used to collect data on child development. Anthropometric measures were used to determine z-scores for weight-for-age (WAZ), length-for-age (LAZ), weight-for-length (WLZ), head circumference (HCZ), and mid-upper arm circumference. Chi-square tests, correlation coefficients, and linear regression analyses were used to relate background variables, nutritional status indicators, and infant development. The prevalence of underweight, stunting, and wasting was 12.1, 24.6, and 4.7%, respectively. Household head education, gender, sanitation, household size, maternal age and education, birth order, poverty likelihood, and CDDS were associated (pdevelopment delay of 1.3% in cognitive and language, and 1.6% in motor development. The ASQ indicated delayed development of 24, 9.1, 25.2, 12.2, and 15.1% in communication, fine motor, gross motor, problem solving, and personal social ability, respectively. All nutritional status indicators except HCZ were positively and significantly associated with development domains. WAZ was the main predictor for all development domains. Undernutrition among infants living in impoverished rural Uganda was associated with household sanitation, poverty, and low dietary diversity. Development domains were positively and significantly associated

  15. Change of residence and functional status within three months and one year following hip fracture surgery

    DEFF Research Database (Denmark)

    Ariza-Vega, Patrocinio; Jiménez-Moleón, José Juan; Kristensen, Morten Tange

    2014-01-01

    those patients who lived alone in their own home at pre-fracture. Implications for Rehabilitation One year after fracture, patients did not recover their previous function, and the activities most affected at the one-year follow-up were: dressing lower body, bathing/showering, transfer bathtub....../shower and walking up/down stairs. After a hip fracture, most recovery of the function happens within the first three months, though some functional activities continue recovering over the first year. Rehabilitation programs cannot be based only on mobility activities, the recovery of other daily living activities......PURPOSE: To study the recovery of patients in terms of 18 activities of daily living and change of residence within the year following a hip fracture. METHOD: This prospective cohort study was carried out in a trauma service of an acute hospital in southern Spain including 159 patients with a hip...

  16. Community mental health status six months after the Sewol ferry disaster in Ansan, Korea.

    Science.gov (United States)

    Yang, Hee Jung; Cheong, Hae Kwan; Choi, Bo Youl; Shin, Min-Ho; Yim, Hyeon Woo; Kim, Dong-Hyun; Kim, Gawon; Lee, Soon Young

    2015-01-01

    The disaster of the Sewol ferry that sank at sea off Korea's southern coast of the Yellow Sea on April 16, 2014 was a tragedy that brought grief and despair to the whole country. The aim of this study was to evaluate the mental health effects of this disaster on the community of Ansan, where most victims and survivors resided. The self-administered questionnaire survey was conducted 4 to 6 months after the accident using the Korean Community Health Survey system, an annual nationwide cross-sectional survey. Subjects were 7,076 adults (≥19 years) living in two victimized communities in Ansan, four control communities from Gyeonggi-do, Jindo and Haenam near the accident site. Depression, stress, somatic symptoms, anxiety, and suicidal ideation were measured using the Center for Epidemiologic Studies-Depression Scale, Brief Encounter Psychosocial Instrument, Patient Health Questionnaire-15, and Generalized Anxiety Disorder 7-Item Scale, respectively. The depression rate among the respondents from Ansan was 11.8%, and 18.4% reported suicidal ideation. Prevalence of other psychiatric disturbances was also higher compared with the other areas. A multiple logistic regression analysis revealed significantly higher odds ratios (ORs) in depression (1.66; 95% confidence interval [CI], 1.36 to 2.04), stress (1.37; 95% CI, 1.10 to 1.71), somatic symptoms (1.31; 95% CI, 1.08 to 1.58), anxiety (1.82; 95% CI, 1.39 to 2.39), and suicidal ideation (1.33; 95% CI, 1.13 to 1.56) compared with Gyeonggi-do. In contrast, the accident areas of Jindo and Haenam showed the lowest prevalence and ORs. Residents in the victimized area of Ansan had a significantly higher prevalence of psychiatric disturbances than in the control communities.

  17. Community mental health status six months after the Sewol ferry disaster in Ansan, Korea

    Directory of Open Access Journals (Sweden)

    Hee Jung Yang

    2015-10-01

    Full Text Available OBJECTIVES: The disaster of the Sewol ferry that sank at sea off Korea’s southern coast of the Yellow Sea on April 16, 2014 was a tragedy that brought grief and despair to the whole country. The aim of this study was to evaluate the mental health effects of this disaster on the community of Ansan, where most victims and survivors resided. METHODS: The self-administered questionnaire survey was conducted 4 to 6 months after the accident using the Korean Community Health Survey system, an annual nationwide cross-sectional survey. Subjects were 7,076 adults (≥19 years living in two victimized communities in Ansan, four control communities from Gyeonggi-do, Jindo and Haenam near the accident site. Depression, stress, somatic symptoms, anxiety, and suicidal ideation were measured using the Center for Epidemiologic Studies-Depression Scale, Brief Encounter Psychosocial Instrument, Patient Health Questionnaire-15, and Generalized Anxiety Disorder 7-Item Scale, respectively. RESULTS: The depression rate among the respondents from Ansan was 11.8%, and 18.4% reported suicidal ideation. Prevalence of other psychiatric disturbances was also higher compared with the other areas. A multiple logistic regression analysis revealed significantly higher odds ratios (ORs in depression (1.66; 95% confidence interval [CI], 1.36 to 2.04, stress (1.37; 95% CI, 1.10 to 1.71, somatic symptoms (1.31; 95% CI, 1.08 to 1.58, anxiety (1.82; 95% CI, 1.39 to 2.39, and suicidal ideation (1.33; 95% CI, 1.13 to 1.56 compared with Gyeonggi-do. In contrast, the accident areas of Jindo and Haenam showed the lowest prevalence and ORs. CONCLUSIONS: Residents in the victimized area of Ansan had a significantly higher prevalence of psychiatric disturbances than in the control communities.

  18. Nutritional and developmental status among 6- to 8-month-old children in southwestern Uganda: a cross-sectional study

    Directory of Open Access Journals (Sweden)

    Grace K. M. Muhoozi

    2016-05-01

    Full Text Available Background: Undernutrition continues to pose challenges to Uganda's children, but there is limited knowledge on its association with physical and intellectual development. Objective: In this cross-sectional study, we assessed the nutritional status and milestone development of 6- to 8-month-old children and associated factors in two districts of southwestern Uganda. Design: Five hundred and twelve households with mother–infant (6–8 months pairs were randomly sampled. Data about background variables (e.g. household characteristics, poverty likelihood, and child dietary diversity scores (CDDS were collected using questionnaires. Bayley Scales of Infant and Toddler Development (BSID III and Ages and Stages questionnaires (ASQ were used to collect data on child development. Anthropometric measures were used to determine z-scores for weight-for-age (WAZ, length-for-age (LAZ, weight-for-length (WLZ, head circumference (HCZ, and mid-upper arm circumference. Chi-square tests, correlation coefficients, and linear regression analyses were used to relate background variables, nutritional status indicators, and infant development. Results: The prevalence of underweight, stunting, and wasting was 12.1, 24.6, and 4.7%, respectively. Household head education, gender, sanitation, household size, maternal age and education, birth order, poverty likelihood, and CDDS were associated (p<0.05 with WAZ, LAZ, and WLZ. Regression analysis showed that gender, sanitation, CDDS, and likelihood to be below the poverty line were predictors (p<0.05 of undernutrition. BSID III indicated development delay of 1.3% in cognitive and language, and 1.6% in motor development. The ASQ indicated delayed development of 24, 9.1, 25.2, 12.2, and 15.1% in communication, fine motor, gross motor, problem solving, and personal social ability, respectively. All nutritional status indicators except HCZ were positively and significantly associated with development domains. WAZ was the main

  19. Use of the Progressive Aphasia Severity Scale (PASS) in monitoring speech and language status in PPA

    Science.gov (United States)

    Sapolsky, Daisy; Domoto-Reilly, Kimiko; Dickerson, Bradford C.

    2014-01-01

    Background Primary progressive aphasia (PPA) is a devastating neurodegenerative syndrome involving the gradual development of aphasia, slowly impairing the patient’s ability to communicate. Pharmaceutical treatments do not currently exist and intervention often focuses on speech-language behavioral therapies, although further investigation is warranted to determine how best to harness functional benefits. Efforts to develop pharmaceutical and behavioral treatments have been hindered by a lack of standardized methods to monitor disease progression and treatment efficacy. Aims Here we describe our current approach to monitoring progression of PPA, including the development and applications of a novel clinical instrument for this purpose, the Progressive Aphasia Severity Scale (PASS). We also outline some of the issues related to initial evaluation and longitudinal monitoring of PPA. Methods & Procedures In our clinical and research practice we perform initial and follow-up assessments of PPA patients using a multi-faceted approach. In addition to standardized assessment measures, we use the PASS to rate presence and severity of symptoms across distinct domains of speech, language, and functional and pragmatic aspects of communication. Ratings are made using the clinician’s best judgment, integrating information from patient test performance in the office as well as a companion’s description of routine daily functioning. Outcomes & Results Monitoring symptom characteristics and severity with the PASS can assist in developing behavioral therapies, planning treatment goals, and counseling patients and families on clinical status and prognosis. The PASS also has potential to advance the implementation of PPA clinical trials. Conclusions PPA patients display heterogeneous language profiles that change over time given the progressive nature of the disease. The monitoring of symptom progression is therefore crucial to ensure that proposed treatments are appropriate at

  20. Docosahexaenoic acid status at 9 months is inversely associated with communicative skills in 3-year-old girls

    DEFF Research Database (Denmark)

    Engel, Sara; Tronhjem, Kathrine Marie Hagerup; Hellgren, Lars

    2013-01-01

    by the parents using third edition of the Ages and Stages Questionnaire (ASQ-3). RBC DHA levels ranged from 2.2% to 12.6% of the RBC fatty acids. The age of reaching milestones correlated with psychomotor development, particularly with gross motor function at 3 years. An association between milestones and later...... personal and social skills was also observed, but only for girls. In girls, RBC-DHA was found to be inversely correlated with communication at 3 years of age (odds ratio = 0.69, 95% confidence interval: 0.56-0.86, P = 0.001), but no other associations with psychomotor development or milestones were found....... The results from study indicate that DHA status at 9 months may not have a pronounced beneficial effect on psychomotor development in early childhood and that communicative skills at 3 years of age may even be inversely associated with early RBC-DHA levels in girls....

  1. Chilean complementary feeding program reduces anemia and improves iron status in children aged 11 to 18 months.

    Science.gov (United States)

    Brito, Alex; Olivares, Manuel; Pizarro, Tito; Rodríguez, Lorena; Hertrampf, Eva

    2013-12-01

    Iron deficiency is the most prevalent nutritional deficiency in the world, primarily affecting infants, young children, and women of childbearing age. To evaluate the impact of the National Complementary Feeding Program (NCFP) on anemia and iron status in Chilean children aged 11 to 18 months. Two studies were performed. The first study was performed at one public outpatient health center in Santiago, using data collected in 1999 (n = 128) and 2000 (n = 125), before and after the national introduction of iron-fortified milk. Subsequently, a study of a representative sample (n = 320) from the two most populated areas of the country was performed in 2009. One year after fortification, the prevalence of anemia was 9%; significantly lower (p < .001) than the 27% prevalence observed 1 year before. Ten years after fortification, 14% of children were anemic and 77% of children with anemia (12% of all children) suffered from iron-deficiency anemia. In 2009, 11% of children consuming iron-fortified milk delivered by the NCFP (73%) were anemic, significantly lower (p = .028) than the 21% prevalence of anemia observed in children without consumption. Consumption of iron-fortified milk was positively associated with hemoglobin concentration (r = 0.28, p = .022) and was associated with a lower prevalence of anemia after adjusting for confounding factors (odds ratio, 0.50; 95% CI, 0.26 to 0.96). In Chile, the NCFP has had an impact on the reduction of anemia and improved the iron status of children aged 11 to 18 months. Increasing the consumption of this iron-fortified milk could enhance the impact of the NCFP.

  2. Energy expenditure, nutritional status, body composition and physical fitness of Royal Marines during a 6-month operational deployment in Afghanistan.

    Science.gov (United States)

    Fallowfield, Joanne L; Delves, Simon K; Hill, Neil E; Cobley, Rosalyn; Brown, Pieter; Lanham-New, Susan A; Frost, Gary; Brett, Stephen J; Murphy, Kevin G; Montain, Scott J; Nicholson, Christopher; Stacey, Michael; Ardley, Christian; Shaw, Anneliese; Bentley, Conor; Wilson, Duncan R; Allsopp, Adrian J

    2014-09-14

    Understanding the nutritional demands on serving military personnel is critical to inform training schedules and dietary provision. Troops deployed to Afghanistan face austere living and working environments. Observations from the military and those reported in the British and US media indicated possible physical degradation of personnel deployed to Afghanistan. Therefore, the present study aimed to investigate the changes in body composition and nutritional status of military personnel deployed to Afghanistan and how these were related to physical fitness. In a cohort of British Royal Marines (n 249) deployed to Afghanistan for 6 months, body size and body composition were estimated from body mass, height, girth and skinfold measurements. Energy intake (EI) was estimated from food diaries and energy expenditure measured using the doubly labelled water method in a representative subgroup. Strength and aerobic fitness were assessed. The mean body mass of volunteers decreased over the first half of the deployment ( - 4·6 (sd 3·7) %), predominately reflecting fat loss. Body mass partially recovered (mean +2·2 (sd 2·9) %) between the mid- and post-deployment periods (Penergy expenditure (mean 15 167 (sd 1883) kJ) measured in a subgroup of volunteers. However, despite the body mass loss, aerobic fitness and strength were well maintained. Nutritional provision for British military personnel in Afghanistan appeared sufficient to maintain physical capability and micronutrient status, but providing appropriate nutrition in harsh operational environments must remain a priority.

  3. Seasonal variation in the nutritional status of children aged 6 to 60 months in a resettlement village in West Timor.

    Science.gov (United States)

    Miller, Jacqueline; Ritchie, Brett; Tran, Cuong; Beggs, Sean; Lada, Christina Olly; Whetter, Kathryn; Cobiac, Lynne

    2013-01-01

    Childhood malnutrition remains a public health issue in Indonesia with a national prevalence of wasting of 13% and stunting of 36%. In rural areas nutritional status depends on local agriculture and may fluctuate in relation to harvest time. The aim of this study was to characterise seasonal variations in nutritional status in two resettlement villages in the Oesao district, Nusa Tenggara Timur. A cross sectional study was conducted in a convenience sample of children after the wet season (March). Children aged 6 to 60 months were assessed for nutritional status using anthropometric and biochemical measures. A subset of these children was re-assessed for anthropometry after the dry season (November). Weight-for-height z scores improved significantly from mean±SD of -1.7± 0.9 in March to -1.3±0.9 in November (p<0.001). There was no significant change in height between seasons. Prevalence of wasting, (weight-for-height z score <-2), was 42% in March and 19% in November (p<0.001). However, stunting rates increased significantly from 42% in March to 45% in November (p<0.001). Thirty six per cent of children were anaemic (Hb level <11 mg/100 mL), 68% were vitamin A deficient (plasma vitamin A level <0.8 μmol/L) and 50% were zinc deficient (plasma zinc <9.94 μmol/L). All children except one were positive for intestinal parasites. These data indicate seasonal changes in anthropometry with inconsistent effects depending on the anthropometric index measured. Wasting and stunting were higher than the national average, alongside high rates of anaemia, zinc and vitamin A deficiencies.

  4. Status and progress of the RERTR program in the year 2004

    International Nuclear Information System (INIS)

    Travelli, A.

    2005-01-01

    The overall status of the RERTR program at the time of the last RERTR meeting is reviewed and the progress achieved since that meeting is described. In the fuel area, unexpected failures of LEU U-Mo dispersion plates and tubes under irradiation testing have prompted a revision of the plans to qualify these fuels. While potential solutions to the difficulties with U-Mo dispersion fuels are being explored in collaboration with our international partners, greater emphasis has been placed on accelerating development of monolithic LEU U-Mo fuel. The feasibility of converting several Russian-designed research reactors to LEU fuels has been addressed, and progress has been made in the development of LEU based 99 Mo production processes. The Russian RERTR program has made significant advances. A very important event of 2004 was the US DOE establishment of the Global Threat Reduction Initiative (GTRI). This new program accelerates and combines under the same US DOE management several programs, including RERTR, which aim to secure, remove, or dispose of, nuclear and other radioactive materials throughout the world that are vulnerable to theft by terrorists. (author)

  5. Attitudes towards digital gap among university students, and its relationship with educational progress and socioeconomic status

    Directory of Open Access Journals (Sweden)

    Z Derikvandi

    2017-03-01

    Full Text Available Introduction: Digital gap may exist in national scale, among organizations and other groups of society, since it is an indicative of inequality in information technology ground and communication. This study aims to investigate the attitude towards digital gap among students, and its relationship with educational progress and socio-economic  status (SES of university students at Alborz University of Medical Sciences. Methods: This was a cross sectional analytic study. students were randomly selected according to multistage cluster method. The tools for collecting data were Davis (1989 questionnaire on attitude towards internet, and  a researcher made questionnaire. The formal validity of the questionnaires is confirmed by a panel of experts, Cronbach's alpha's coefficient was also calculated. Pearson coefficient were calculated andindependent T- test was used for analyzing the data. Result: The analysis of data indicates that there is a meaningful relationship between the attitude towards digital gap and educational progress, and also SES of the students. Furthermore, there was adifferences between the attitudes of males (48.7 and felames (46.5 toward digital gap (p=0.01. Conclusion:There is an attitude towards digital gap in university students. Interventions are needed to close the digital gaps in studnets.

  6. Progress Monitoring in Reading: Comparison of Weekly, Bimonthly, and Monthly Assessments for Students at Risk for Reading Difficulties in Grades 2-4

    Science.gov (United States)

    January, Stacy-Ann A.; Van Norman, Ethan R.; Christ, Theodore J.; Ardoin, Scott P.; Eckert, Tanya L.; White, Mary Jane

    2018-01-01

    The present study examined the utility of two progress monitoring assessment schedules (bimonthly and monthly) as alternatives to monitoring once weekly with curriculum-based measurement in reading (CBM-R). General education students (N = 93) in Grades 2-4 who were at risk for reading difficulties but not yet receiving special education services…

  7. Wills plasma physics department thirty second 6-monthly progress report 1st July-31st December 1976

    International Nuclear Information System (INIS)

    1976-01-01

    Progress is reported on research programs which are proceeding in the following topics: plasma sources, hydromagnetic shock waves, rotating plasmas, magnetohydrodynamics, laser diagnostics and far infrared interferometry. (J.R.)

  8. Wills Plasma Physics department thirty first 6-monthly progress report 1st January-30th June 1976

    International Nuclear Information System (INIS)

    1976-01-01

    Progress is reported on research programs which are proceeding in the following topics: plasma sources, hydromagnetic shock waves, rotating plasmas, magnetohydrodynamics, laser diagnostics and far infrared interferometry. (R.L.)

  9. Progress and status of the integral fast reactor (IFR) fuel cycle development

    International Nuclear Information System (INIS)

    Till, C.E.; Chang, Y.I.

    1993-01-01

    The Integral Fast Reactor (IFR) fuel cycle holds promise for substantial improvements in economics, diversion-resistance, and waste management. This paper discusses technical features of the IFR fuel cycle, its technical progress, the development status, and the future plans and directions. The Integral Fast Reactor (IFR) fuel cycle, is based on the use of a metallic fuel alloy (U-Pu-Zr) that permits use of an innovative method for processing of spent fuel. This method, a combination of pyrometallurgical and electrochemical processes, has been termed pyroprocessing. It offers the advantages of a simple, compact processing system and limited volumes of stabilized high-level wastes. This translates to an economically viable system that is likely to receive favorable public response, particularly when combined with the other attributes of the Integral Fast Reactor. Substantial progress has been made in the development of the IFR pyroprocessing method. A comprehensive demonstration of the process will soon begin at the Argonne National Laboratory Idaho site, using spent fuel from the EBR-II reactor. An important advantage of the IFR is its ability to recycle fuel in the process of power generation, extending fuel resources by a considerable amount and assuring the continued viability of nuclear power stations by reducing dependence on external fuel supplies. Pyroprocessing is the means whereby the recycle process is accomplished. It can also be applied to the recovery of fuel constituents from spent fuel generated in the process of operation of conventional light water reactor power plants, offering the means to recover the valuable fuel resources remaining in that material

  10. Cognitive status is a determinant of health resource utilization among individuals with a history of falls: a 12-month prospective cohort study.

    Science.gov (United States)

    Davis, J C; Dian, L; Khan, K M; Bryan, S; Marra, C A; Hsu, C L; Jacova, P; Chiu, B K; Liu-Ambrose, T

    2016-03-01

    Falls are a costly public health problem worldwide. The literature is devoid of prospective data that identifies factors among fallers that significantly drive health care resource utilization. We found that cognitive function--specifically, executive functions--and cognitive status are significant determinants of health resource utilization among older fallers. Although falls are costly, there are no prospective data examining factors among fallers that drive health care resource utilization. We identified key determinants of health resource utilization (HRU) at 6 and 12 months among older adults with a history of falls. Specifically, with the increasing recognition that cognitive impairment is associated with increased falls risk, we investigated cognition as a potential driver of health resource utilization. This 12-month prospective cohort study at the Vancouver Falls Prevention Clinic (n = 319) included participants with a history of at least one fall in the previous 12 months. Based on their cognitive status, participants were divided into two groups: (1) no mild cognitive impairment (MCI) and (2) MCI. We constructed two linear regression models with HRU at 6 and 12 months as the dependent variables for each model, respectively. Predictors relating to mobility, global cognition, executive functions, and cognitive status (MCI versus no MCI) were examined. Age, sex, comorbidities, depression status, and activities of daily living were included regardless of statistical significance. Global cognition, comorbidities, working memory, and cognitive status (MCI versus no MCI ascertained using the Montreal Cognitive Assessment (MoCA)) were significant determinants of total HRU at 6 months. The number of medical comorbidities and global cognition were significant determinants of total HRU at 12 months. MCI status was a determinant of HRU at 6 months among older adults with a history of falls. As such, efforts to minimize health care resource use related to falls

  11. Model Agreements for the granting of Associate Member Status Implementation arrangements concerning eligibility for personnel appointments and industrial participation for Associate Member States Progress report by the Management

    CERN Document Server

    2011-01-01

    Model Agreements for the granting of Associate Member Status Implementation arrangements concerning eligibility for personnel appointments and industrial participation for Associate Member States Progress report by the Management

  12. Junk Food Consumption and Effects on Growth Status among Children Aged 6-24 Months in Mashhad, Northeastern Iran

    Directory of Open Access Journals (Sweden)

    Rahim Vakili

    2015-08-01

    Full Text Available Introduction Junk food, due to the lack of vitamins, minerals and trace amounts of energy and protein, there is the risk that the child's stomach filled and by reducing her/his appetite, reduce the chance of nutritious foods. So it is necessary to determine the relationship between using of junk food with growth rate in children. Materials and Methods This cross-sectional descriptive-analytic study was conducted on 300 mothers and their babies , who were referring to 10 selected Mashhad health-care centers for monitoring their 6-24 months children. Participants were selected by cluster and simple random sampling and valid and reliable   questionnaire was used to collect data. Data were analyzed by descriptive- analytic statistics and using SPSS version 16. Results In growth chart, 86.7 percent of children showed appropriate growth, 10.3 percent had delayed growth and 3 percent had horizontal growth curve. In 11.3 percent of families, the junk food has been used for children regularly, 44.7 percent did not believe in these snacks and 44 percent of mothers sometimes used this junk food for their children. Results showed the statistical correlation between junk food consumption and  growth status of children was significant, so children whom haven’t had junk food, have grown more favorable than the other kids (P

  13. Selective attention neutralizes the adverse effects of low socioeconomic status on memory in 9-month-old infants.

    Science.gov (United States)

    Markant, Julie; Ackerman, Laura K; Nussenbaum, Kate; Amso, Dima

    2016-04-01

    Socioeconomic status (SES) has a documented impact on brain and cognitive development. We demonstrate that engaging spatial selective attention mechanisms may counteract this negative influence of impoverished environments on early learning. We previously used a spatial cueing task to compare target object encoding in the context of basic orienting ("facilitation") versus a spatial selective attention orienting mechanism that engages distractor suppression ("IOR"). This work showed that object encoding in the context of IOR boosted 9-month-old infants' recognition memory relative to facilitation (Markant and Amso, 2013). Here we asked whether this attention-memory link further interacted with SES in infancy. Results indicated that SES was related to memory but not attention orienting efficacy. However, the correlation between SES and memory performance was moderated by the attention mechanism engaged during encoding. SES predicted memory performance when objects were encoded with basic orienting processes, with infants from low-SES environments showing poorer memory than those from high-SES environments. However, SES did not predict memory performance among infants who engaged selective attention during encoding. Spatial selective attention engagement mitigated the effects of SES on memory and may offer an effective mechanism for promoting learning among infants at risk for poor cognitive outcomes related to SES. Copyright © 2015 The Authors. Published by Elsevier Ltd.. All rights reserved.

  14. Maternal and infant vitamin D status during the first 9 months of infant life-a cohort study

    DEFF Research Database (Denmark)

    Við Streym, S; Kristine Moller, U; Rejnmark, Lars

    2013-01-01

    /l), with increasing levels (P3.08 (2.67-3.92  pmol/l) at the last visit. Vitamin D levels were not associated with anthropometric indices of the newborn infant or their growth during follow-up. CONCLUSIONS: Vitamin D deficiency is widespread in newborn. Maternal 25OHD levels above 50  nmol......BACKGROUND/OBJECTIVES: The objective of this study was to assess vitamin D status and possible consequences of low plasma 25-hydroxyvitamin D (25OHD) levels in a population of healthy mothers and their infants.Subjects/methods:A total of 107 women aged 24-41 years gave birth to 108 infants....... They were followed up three times during 9 months. RESULTS: Cord blood 25OHD level (43.3 ± 20.4  nmol/l) on average was 62 ± 16% of maternal levels (73.3 ± 30.7  nmol/l), measured 1-2 weeks postpartum. Cord blood 25OHD correlated positively with maternal 25OHD levels (r=0.83, P

  15. Multiple sclerosis in South America: month of birth in different latitudes does not seem to interfere with the prevalence or progression of the disease

    Directory of Open Access Journals (Sweden)

    Yara Dadalti Fragoso

    2013-09-01

    Full Text Available Objective To assess whether the month of birth in different latitudes of South America might influence the presence or severity of multiple sclerosis (MS later in life. Methods Neurologists in four South American countries working at MS units collected data on their patients' month of birth, gender, age, and disease progression. Results Analysis of data from 1207 MS patients and 1207 control subjects did not show any significant variation in the month of birth regarding the prevalence of MS in four latitude bands (0–10; 11–20; 21–30; and 31–40 degrees. There was no relationship between the month of birth and the severity of disease in each latitude band. Conclusion The results from this study show that MS patients born to mothers who were pregnant at different Southern latitudes do not follow the seasonal pattern observed at high Northern latitudes.

  16. The Goddard Integral Field Spectrograph at Apache Point Observatory: Current Status and Progress Towards Photon Counting

    Science.gov (United States)

    McElwain, Michael W.; Grady, Carol A.; Bally, John; Brinkmann, Jonathan V.; Bubeck, James; Gong, Qian; Hilton, George M.; Ketzeback, William F.; Lindler, Don; Llop Sayson, Jorge; Malatesta, Michael A.; Norton, Timothy; Rauscher, Bernard J.; Rothe, Johannes; Straka, Lorrie; Wilkins, Ashlee N.; Wisniewski, John P.; Woodgate, Bruce E.; York, Donald G.

    2015-01-01

    We present the current status and progress towards photon counting with the Goddard Integral Field Spectrograph (GIFS), a new instrument at the Apache Point Observatory's ARC 3.5m telescope. GIFS is a visible light imager and integral field spectrograph operating from 400-1000 nm over a 2.8' x 2.8' and 14' x 14' field of view, respectively. As an IFS, GIFS obtains over 1000 spectra simultaneously and its data reduction pipeline reconstructs them into an image cube that has 32 x 32 spatial elements and more than 200 spectral channels. The IFS mode can be applied to a wide variety of science programs including exoplanet transit spectroscopy, protostellar jets, the galactic interstellar medium probed by background quasars, Lyman-alpha emission line objects, and spectral imaging of galactic winds. An electron-multiplying CCD (EMCCD) detector enables photon counting in the high spectral resolution mode to be demonstrated at the ARC 3.5m in early 2015. The EMCCD work builds upon successful operational and characterization tests that have been conducted in the IFS laboratory at NASA Goddard. GIFS sets out to demonstrate an IFS photon-counting capability on-sky in preparation for future exoplanet direct imaging missions such as the AFTA-Coronagraph, Exo-C, and ATLAST mission concepts. This work is supported by the NASA APRA program under RTOP 10-APRA10-0103.

  17. Wills plasma physics department twenty-eighth 6-monthly progress report 1st July-31st December 1974

    International Nuclear Information System (INIS)

    1975-01-01

    Progress is reported on several research programs which include: 1) plasma sources, 2) hydromagnetic shock waves, 3) rotating plasmas, 4) icr heating and magnetoacoustic heating, 5) carbon dioxide laser interferometer, 6) dye lasers, and 7) plasmascanned Michelson interferometer. (R.L.)

  18. Proton Pump Inhibitors Intake and Iron and Vitamin B12 Status: A Prospective Comparative Study with a Follow up of 12 Months

    OpenAIRE

    Qorraj-Bytyqi, Hasime; Hoxha, Rexhep; Sadiku, Shemsedin; Bajraktari, Ismet H.; Sopjani, Mentor; Thaçi, Kujtim; Thaçi, Shpetim; Bahtiri, Elton

    2018-01-01

    BACKGROUND: Proton pump inhibitors (PPIs) represent the most widely prescribed antisecretory agents, but their prolonged use, may influence iron and vitamin B12 status, which could have important implications for clinical practice. AIM: We undertook this study aiming to investigate the association between PPIs use for 12 months and potential changes in iron and vitamin B12 status, as well as whether this potential association varies among four specific PPI drugs used in the study. MET...

  19. Kootenai River Fisheries Investigation : Stock Status of Burbot : Project Progress Report 2008 Annual Report.

    Energy Technology Data Exchange (ETDEWEB)

    Paragamian, Valughn L.; Laude Dorothy C.

    2008-12-26

    Objectives of this investigation were to (1) monitor the population status and recruitment of burbot Lota lota in the Kootenai River, Idaho and British Columbia, Canada during the winter of 2006-2007; (2) evaluate the selective withdrawal system in place at Libby Dam to maintain the river temperature near Bonners Ferry between 1-4 C (November-December) to improve burbot migration and spawning activity; and (3) determine if a hatching success of 10% of eyed burbot embryos could be achieved through extensive rearing and produce fingerlings averaging 9.8 cm in six months. Water temperature did not fall below the upper limit (4 C) until mid-January but was usually maintained between 1-4 C January through February and was acceptable. Snowpack was characterized by a 101% of normal January runoff forecast. Adult burbot were sampled with hoop nets and slat traps. Only three burbot were captured in hoop nets, all at Ambush Rock (rkm 244.5). No burbot were caught in either slat traps or juvenile sampling gear, indicating the population is nearly extirpated. Burbot catch per unit effort in hoop nets was 0.003 fish/net d. Extensive rearing was moved to a smaller private pond and will be reported in the 2008-2009 annual report.

  20. Industrial Fuel Gas Demonstration Plant Program. Monthly, quarterly and annual progress report, December 1978 and Calender Year 1978

    Energy Technology Data Exchange (ETDEWEB)

    None

    1978-01-01

    A new pilot plant program developed by DOE and the team members, was started on September 20, 1978. Pilot plant success was achieved in obtaining an ash balanced condition for several days with ash agglomeration with a pure coal feed. This was the objective of the first three months of the approved program.

  1. The effect of a micronutrient-fortified complementary food on micronutrient status, growth and development of 6- to 12-month-old disadvantaged urban South-African infants

    NARCIS (Netherlands)

    Oelofse, A.; Raaij, van J.M.A.; Benade, A.J.S.; Dhansay, M.A.; Tolboom, J.J.M.; Hautvast, J.G.A.J.

    2003-01-01

    The study was conducted to look at the effectiveness of a multimicronutrient-fortified complementary food on the micronutrient status, linear growth and psychomotor development of 6- to 12-month-old infants from a black urban disadvantaged community in the Western Cape, South Africa. The study was

  2. Effect of dietary fat supplementation during late pregnancy and first six months of lactation on maternal and infant vitamin A status in rural Bangladesh

    NARCIS (Netherlands)

    Alam, D.S.; Raaij, van J.M.A.; Hautvast, J.G.A.J.; Yunus, M.; Wahed, M.A.; Fuchs, G.J.

    2010-01-01

    Dietary fat intake is extremely low in most communities with vitamin A deficiency. However, its role in vitamin A status of pregnant and lactating women is poorly understood. The aim of the study was to examine the effect of supplementing women with fat from mid-/late pregnancy until six months

  3. The course of health status and (health-related) quality of life following fracture of the lower extremity : A 6-month follow-up study

    NARCIS (Netherlands)

    van Son, Marleen; de Vries, J.; Roukema, J.A.; Gosens, T.; Verhofstad, M. H. J.; den Oudsten, B.L.

    2016-01-01

    Purpose The aim of this prospective study was to describe the course of health status (HS), health-related quality of life, and quality of life (QOL) in patients with lower extremity fractures (LEF) up to 6 months post-fracture. Methods Patients (n = 171; age range 18–100 years) completed the World

  4. The course of health status and (health-related) quality of life following fracture of the lower extremity: a 6-month follow-up study

    NARCIS (Netherlands)

    M.A.C. van Son; J. de Vries (Jolanda); J.A. Roukema; T. Gosens; M.H.J. Verhofstad (Michiel); B.L. den Oudsten (Brenda)

    2016-01-01

    textabstractPurpose: The aim of this prospective study was to describe the course of health status (HS), health-related quality of life, and quality of life (QOL) in patients with lower extremity fractures (LEF) up to 6 months post-fracture. Methods: Patients (n = 171; age range 18–100 years)

  5. Acid-base status at birth, spontaneous motor behaviour at term and 3 months and neurodevelopmental outcome at age 4 years in full-term infants

    NARCIS (Netherlands)

    Wildschut, J; Feron, FJM; Hendriksen, JGM; van Hall, M; Gavilanes-Jiminez, DWD; Hadders-Algra, M; Vles, JSH

    Objective: The aim of the study was to assess the relationship between acid-base status and quality and quantity of General Movements (GMs) at birth and quality of GMs at age 3 months and motor, cognitive and behavioural functioning at the age of 4 years. Methods: From a cohort of 84 term children

  6. Line-focus solar central power systems, Phase I. Monthly technical progress report, 31 January 1979-28 February 1979

    Energy Technology Data Exchange (ETDEWEB)

    Slemmons, A J

    1979-03-01

    The work performed during the fifth month of the Phase I study of the High Temperature Line-Focus Solar Central Power System is summarized. During the reporting period, the optical and receiver computer analysis programs and parametricized data have been combined in a computer program to give the projected annualized Bus Bar Energy Costs for a specified design. Although some of the data are incomplete or need further refinement, the program has been used to examine the sensitivity of some parameters, and to make preliminary optimizations.

  7. ASSOCIATION OF NUTRITIONAL STATUS WITH LUNG FUNCTION AND MORBIDITY IN CHILDREN AND ADOLESCENTS WITH CYSTIC FIBROSIS: A 36-MONTH COHORT STUDY.

    Science.gov (United States)

    Hauschild, Daniela Barbieri; Rosa, Anauã Franco; Ventura, Julia Carvalho; Barbosa, Eliana; Moreira, Emília Addison Machado; Ludwig Neto, Norberto; Moreno, Yara Maria Franco

    2018-01-01

    To evaluate the association between nutritional status, lung function and morbidity in a 36-month cohort in children and adolescents with cystic fibrosis. Prospective cohort of children and adolescents with cystic fibrosis aged 1-15 years. At the baseline, the nutritional status was determined by weight-for-height and body mass index-for-age for children 36 months. Those classified bellow the 50th percentile had a RR of 4.61 (95%CI 0.89; 23.81) to present the same outcome. Nutritional status was not a risk factor for morbidity in this cohort. Nutritional deficit was associated with impaired lung function, but not with morbidity in children and adolescents with cystic fibrosis.

  8. The progression of 102 Brazilian patients with bipolar disorder: outcome of first 12 months of prospective follow-up

    Directory of Open Access Journals (Sweden)

    Fernanda Novis

    2014-03-01

    Full Text Available INTRODUCTION: Prospective studies have shown that the course of bipolar disorder (BD is characterized by the persistence of symptoms, predominantly depression, along most of the time. However, to our knowledge, no studies in Latin America have investigated it. OBJECTIVES: To replicate international studies using a Brazilian sample to prospectively analyze treatment outcomes in the first year and to determine potential chronicity factors. METHODS: We followed up 102 patients with BD for 12 months and evaluated the number of months with affective episodes and the intensity of manic and depressive symptoms using the Young Mania Rating Scale (YMRS and the Hamilton Depression Scale (HAM-D17. Sociodemographic and retrospective clinical data were examined to determine possible predictors of outcome. RESULTS: Almost 50% of the patients had symptoms about half of the time, and there was a predominance of depressive episodes. Disease duration and number of depressive episodes were predictors of chronicity. Depressive polarity of the first episode and a higher number of depressive episodes predicted the occurrence of new depressive episodes. CONCLUSION: In general, BD outcome seems to be poor in the first year of monitoring, despite adequate treatment. There is a predominance of depressive symptoms, and previous depressive episodes are a predictor of new depressive episodes and worse outcome.

  9. The course of health status and (health-related) quality of life following fracture of the lower extremity: a 6-month follow-up study.

    Science.gov (United States)

    Van Son, M A C; De Vries, J; Roukema, J A; Gosens, T; Verhofstad, M H J; Den Oudsten, B L

    2016-05-01

    The aim of this prospective study was to describe the course of health status (HS), health-related quality of life, and quality of life (QOL) in patients with lower extremity fractures (LEF) up to 6 months post-fracture. Patients (n = 171; age range 18-100 years) completed the World Health Organization Quality of Life assessment instrument-Bref (WHOQOL-Bref) and the Short Musculoskeletal Function Assessment questionnaire (SMFA) at time of diagnosis (i.e., pre-injury status), 1 week, and 6 months post-fracture. Linear mixed modeling was performed. Interaction effects of time with treatment were detected for the WHOQOL-Bref facet Overall QOL and General health (p = .002) and Physical health (p = .003). Patients did not return to their pre-injury Physical health, Psychological health, and Environment 6 months post-fracture (p choice of the questionnaire influences the derived conclusions. LEF did not affect satisfaction with social relationships.

  10. Role of p53 status in radiation sensitivity and cell cycle progression

    International Nuclear Information System (INIS)

    Zellars, Richard C.; Loney, Tania; Schott, Ann F.; Davis, Mary A.; Maybaum, Jonathan; Clarke, Michael F.; Lawrence, Theodore S.

    1995-01-01

    Purpose: Although p53 function plays a major role in G1 arrest after radiation, the influence of p53 status on progress through other phases of the cell cycle and on radiation sensitivity of human tumors is less clear. We investigated these issues using cells with a conditional expression system for wild type p53. Methods: A temperature sensitive murine wild type p53 plasmid was used (Ginsberg D, et al: Mol. Cell.Biol . 11:582, 1991). At the permissive temperature (32 deg. C), this plasmid produces a protein which assumes a conformation that exhibits wild type p53 function. However, when cells are cultured at 38 deg. C, this protein assumes an inactive conformation. HT29 human colon cancer cells (which are p53 mutant) were transduced with this plasmid (designated PEP A and PEP G cells) or a control vector (designated CCH1 cells) using electroporation and Geneticin selection. The presence of murine p53 transcript in the PEP cells was confirmed by Northern analysis. Results: Cells were cultured under 3 conditions: 1) 38 deg. C at all times; 2) 32 deg. C for 24 hours prior to irradiation and 3) 32 deg. C for 24 hours after irradiation. We found that culturing under permissive temperatures produced a small decrease in surviving fraction in the PEP clones (0.61 ± 0.10 and 0.64 ± 0.07, for PEP A and G, respectively) but not the CCH1 controls (1.14 ± 0.15). PEP cells tended to be more radiosensitive than CCH1 cells (even under non-permissive conditions) and demonstrated a trend towards increased radiosensitivity under both Conditions 2 and 3. In addition, flow cytometry revealed that a 24 hour exposure to permissive conditions increased the fraction of cells in G1 slightly and in G2/M substantially. S phase was almost absent. Conclusion: Restoration of p53 function in HT29 human colon cancer cells using this temperature sensitive system produced increased cytotoxicity and radiation sensitivity as well as cell cycle redistribution. It will be important to assess the

  11. Influence of combined therapy with prospidin and methotrexate on radiological progression, functional status and quality of life in pts with rheumatoid arthritis

    Directory of Open Access Journals (Sweden)

    O. V. Simonova

    2004-01-01

    Full Text Available Objective. To evaluate influence of combination therapy with prospidin (P and methotrexate (MTX on X-ray progression, functional status (FS and quality of life (QL in patients with rheumatoid arthritis (RA in comparison with MTX monotherapy. Material and methods. 143 RA pts (129 female and 14 male were studied. Of them, there were. Mean age was 45.5±5.l years. Average duration of the disease was 4.5 years. 20 pts had II and 123 - 111 degree of RA activity. The second X-ray stage according to Steinbroker dominated. 72 pts of group I received P+MTX combination therapy. The therapy included intravenous drip-feed of P 200-300 mg per week in 200ml of 5% glucose and MTX 10 mg per week 1M. The maintaining therapy included P 100-200 mg per week IM and MTX 10 mg per week. 71 patients of group II received MTX monotherapy 10 mg per week. X-ray progression assessment was performed according to Sharp method. FS was evaluated with the HAQ questionnaire, Lee test. QL was evaluated with SF-36 scale. Pts were examined before and after I, 2, 3, 6 and 12 months of treatment. Results. There was no increase of X-ray progression of the disease in case of P+MTX therapy as compared with MTX monotherapy. Both methods resulted in improvement of FS parameters and physical health. Combination therapy significantly improved psychological health as well.

  12. [Anemia and nutritional status of infants from two to five months of age treated in facilities of the Ministry of Health of Peru, 2012].

    Science.gov (United States)

    Gómez-Guizado, Guillermo; Munares-García, Oscar

    2014-01-01

    Determine the characteristics of the levels of anemia in infants from two to five months of age treated in facilities of the Ministry of Health of Peru during 2012. This cross-sectional study uses the nutritional status information system of the National Center for Food and Nutrition, National Institute of Health of Peru in 2012. Records of 7,513 infants from two to five months of age treated in small outpatient clinics, centers and hospitals of the Ministry of Health of Peru's 25 regions were analyzed. Descriptive statistics and logistic regression techniques were used for data analysis. 10.2% (95% CI 9.5-10.9) of the infants had anemia, with frequency differences by month of age (panemia were: age of 4 months (OR 1.2; 95% CI 1.0-1.5), age of 5 months (OR 1.4; 95% CI 1.2-1.6), obesity (OR 0.7; 95% CI 0.5-1.0) and chronic malnutrition (OR 1.3; 95% CI 1.0-1.6). The presence of anemia and chronic malnutrition before 6 months of age was evidenced, as well as that the probability of anemia increases with age and is associated with some components of nutritional status.

  13. Progression of emphysema in a 12-month hyperpolarized 3He-MRI study: lacunarity analysis provided a more sensitive measure than standard ADC analysis

    DEFF Research Database (Denmark)

    Diaz, Sandra; Casselbrant, Ingrid; Piitulainen, Eeva

    2009-01-01

    RATIONALE AND OBJECTIVES: Inhaled hyperpolarized (3)He magnetic resonance (MR) imaging has been used to measure alveolar size in patients with emphysema. The aim of this study was to test the hypothesis that (3)He MR images could be used to develop a biomarker of emphysema progression. MATERIALS...... AND METHODS: Twelve healthy controls and 18 patients with emphysema (eight current smokers, 10 ex-smokers) were imaged at baseline and 6 and 12 months. An additional nine subjects with alpha-1 antitrypsin deficiency (four with emphysema, six without symptoms) were also imaged at baseline and at 6 months. Each...... subject was imaged at two lung volumes: functional residual capacity (FRC) and FRC plus 15% of total lung capacity. Means and standard deviations of apparent diffusion coefficients (ADCs) were calculated from coronal images of the entire lung and correlated with pulmonary function test results...

  14. Anemia and nutritional status of infants from two to five months of age treated in facilities of the Ministry of Health of Peru, 2012

    OpenAIRE

    Gómez-Guizado, Guillermo; Centro Nacional de Alimentación y Nutrición, Instituto Nacional de Salud. Lima, Perú. Médico cirujano especialista en Epidemiologia de Campo; Munares-García, Oscar; Centro Nacional de Alimentación y Nutrición, Instituto Nacional de Salud. Lima, Perú. Facultad de Medicina, Universidad Nacional Mayor de San Marcos. Lima, Perú. licenciado en Obstetricia, magíster en Salud Pública

    2014-01-01

    Objectives. Determine the characteristics of the levels of anemia in infants from two to five months of age treated in facilities of the Ministry of Health of Peru during 2012. Materials and methods. This cross-sectional study uses the nutritional status information system of the National Center for Food and Nutrition, National Institute of Health of Peru in 2012. Records of 7,513 infants from two to five months of age treated in small outpatient clinics, centers and hospitals of the Ministry...

  15. Corpus callosum atrophy as a marker of clinically meaningful cognitive decline in secondary progressive multiple sclerosis. Impact on employment status.

    Science.gov (United States)

    Papathanasiou, Athanasios; Messinis, Lambros; Zampakis, Petros; Papathanasopoulos, Panagiotis

    2017-09-01

    Cognitive impairment in Multiple Sclerosis (MS) is more frequent and pronounced in secondary progressive MS (SPMS). Cognitive decline is an important predictor of employment status in patients with MS. Magnetic Resonance Imaging (MRI) markers have been used to associate tissue damage with cognitive dysfunction. The aim of the study was to designate the MRI marker that predicts cognitive decline in SPMS and explore its effect on employment status. 30 SPMS patients and 30 healthy participants underwent neuropsychological assessment using the Trail Making Test (TMT) parts A and B, semantic and phonological verbal fluency task and a computerized cognitive screening battery (Central Nervous System Vital Signs). Employment status was obtained as a quality of life measure. Brain MRI was performed in all participants. We measured total lesion volume, third ventricle width, thalamic and corpus callosum atrophy. The frequency of cognitive decline for our SPMS patients was 80%. SPMS patients differed significantly from controls in all neuropsychological measures. Corpus callosum area was correlated with cognitive flexibility, processing speed, composite memory, executive functions, psychomotor speed, reaction time and phonological verbal fluency task. Processing speed and composite memory were the most sensitive markers for predicting employment status. Corpus callosum area was the most sensitive MRI marker for memory and processing speed. Corpus callosum atrophy predicts a clinically meaningful cognitive decline, affecting employment status in our SPMS patients. Copyright © 2017 Elsevier Ltd. All rights reserved.

  16. The Status of Women in Physics in the U.S.: Progress and New Actions

    Science.gov (United States)

    Xie, Aihua

    2005-10-01

    The 2005 Chair of the American Physical Society Committee on the Status of Women in Physics describes the committee's recent activities to recognize distinguished women physicists, improve the climate for women in physics, and provide leadership training for women in physics. The committee's response to the Harvard University president's suggestion of innate gender differences as regards women's representation in math and science is also discussed, as well as some encouraging developments in the status of women in physics in the U.S.

  17. Decreased serum hepcidin, inflammation, and improved functional iron status six-months post-restrictive bariatric surgery.

    Science.gov (United States)

    Excess adiposity is associated with low-grade inflammation and decreased iron status. Iron depletion (ID) in obesity is thought to be mediated by an inflammation-induced increase in the body’s main regulator of iron homeostasis, hepcidin. Elevated hepcidin can result in ID as it prevents the release...

  18. Self-perceived recovery status among Danish people with low back problems; what influences their appraisal after 12 months?

    DEFF Research Database (Denmark)

    Myburgh, Corrie; Boyle, Eleanor; Lauridsen, Henrik Hein

    /trauma and positive coping experiences. Those unsure of their status, tended to do so on the basis of cognitive dissonance regarding the meaning of recovery and paradoxical scepticism of pain-free periods. Retrospective self-appraisal appears to be filtered through the individual’s understanding of the nature...

  19. Effects of low calcium dialysate on the progression of coronary artery calcification in hemodialysis patients: An open-label 12-month randomized clinical trial.

    Science.gov (United States)

    Kim, Soo Jin; Lee, Young-Ki; Oh, Jieun; Cho, AJin; Noh, Jung Woo

    2017-09-15

    The association between the dialysate calcium level and coronary artery calcification (CAC) has not yet been evaluated in hemodialysis patients. The objective of this study was to determine whether lowering the dialysate calcium levels would decrease the progression of coronary artery calcification (CAC) compared to using standard calcium dialysate. We conducted an open-label randomized trial with parallel groups. The patients were randomly assigned to either 12-month treatment with low calcium dialysate (LCD; 1.25mmol/L, n=36) or standard calcium dialysate (SCD; 1.5mmol/L, n=40). The primary outcome was the change in the CAC scores assessed by 64-slice multidetector computed tomography after 12months. During the treatment period, CAC scores increased in both groups, especially significant in LCD group (402.5±776.8, 580.5±1011.9, P=0.004). When we defined progressors as patients at second and third tertiles of CAC changes, progressor group had a higher proportion of LCD-treated patients than SCD-treated patients (P=0.0229). In multivariate analysis, LCD treatment is a significant risk factor for increase in CAC scores (odds ratio=5.720, 95% CI: 1.219-26.843, P=0.027). Use of LCD may accelerate the progression of CAC in patients with chronic hemodialysis over a 12-month period. Clinical Research Information Service [Internet]; Osong (Chungcheongbuk-do): Korea Centers for Disease Control and Prevention, Ministry of Health and Welfare (Republic of Korea), 2010: KCT0000942. Available from: https://cris.nih.go.kr/cris/search/search_result_st01_kren.jsp?seq=3572&sLeft=2&type=my. Copyright © 2017 Elsevier Ireland Ltd. All rights reserved.

  20. Household Food Insecurity and Its Association with Nutritional Status of Children 6-59 Months of Age in East Badawacho District, South Ethiopia.

    Science.gov (United States)

    Betebo, Bealu; Ejajo, Tekle; Alemseged, Fissahaye; Massa, Desalegn

    2017-01-01

    Background . Ethiopia has one of the highest child malnutrition rates in the world. Food insecurity is one of the determinant factors of malnutrition in developing countries; however its role remains unclear. Objective . To assess household food insecurity and its association with the nutritional status of children 6-59 months of age in East Badawacho District, South Ethiopia. Methods . A community based cross-sectional study was conducted from February 20 to 30, 2014 on a sample of 508 mother/child pairs of 6-59-month-old children. Sample households with eligible children were selected using systematic random sampling technique. Both bivariate and multivariate analysis were used to identify factors associated with nutritional status of children. P value of insecurity was 75.8%. The prevalence rates of stunting, underweight, and wasting among children were 45.6%, 26.3%, and 14.6%, respectively. Household food insecurity was significantly associated with underweight (AOR = 3.82; CI = 1.78-8.19) and stunting (AOR = 6.7; CI = 3.71-12.1) but not with wasting. Conclusion and Recommendation . Household food insecurity and the prevalence rates of stunting, underweight, and wasting, among children 6 to 59 months, were high. Intervention programs should focus on improving household food insecurity and nutritional status of children.

  1. Is work organisation associated with work status 3 months after injury? Results from a case-control study of New Zealand workers.

    Science.gov (United States)

    Lilley, Rebbecca; Derrett, Sarah; Davie, Gabrielle

    2015-01-01

    Little empirical examination of the relationship between work organisational factors and return to work following injury has been undertaken despite the growing recognition of examining broader multi-dimensional contexts for recovery following injury. To explore relationships between pre-injury work organisational factors and work status (working/work absent) 3-month after injury among people employed prior to injury. Cases (work absent) and controls (working), selected from a larger study of injury outcomes according to reported work status 3-month after injury, completed a postal questionnaire. Work organisational factors were compared between cases and controls using univariate and multivariable analyses. One hundred and twelve participants completed the questionnaire (44 cases; 68 controls). Of 11 work organisation factors examined, organisational size was the only explanatory variable significantly associated with work status in the multivariable model. Higher odds of work absence were found in small ( 500 employees) (OR 7.2) workplaces, compared with medium-sized (50-500 employees) organisations. Variations in post-injury work patterns among those working pre-injury may be partly explained by organisation size. Future research examining work status following injury should examine the influence of work organisational factors in larger studies.

  2. Digit Sucking Habit and Association with Dental Caries and Oral Hygiene Status of Children Aged 6 Months to 12 Years Resident in Semi-Urban Nigeria.

    Science.gov (United States)

    Kolawole, Kikelomo Adebanke; Folayan, Morenike Oluwatoyin; Agbaje, Hakeem Olatunde; Oyedele, Titus Ayodeji; Oziegbe, Elizabeth Obhioneh; Onyejaka, Nneka Kate; Chukwumah, Nneka Maureen; Oshomoji, Olusegun Victor

    2016-01-01

    Non-nutritive sucking (NNS) is a common behavior in childhood. The association between digit sucking, dental caries and oral health has been studied with inconclusive results. The objectives of this study were to determine the prevalence of, and the association between digit sucking, caries and oral hygiene status of children age six months to 12 years, resident in Ile-Ife, Osun State, Nigeria. A cross-sectional study was conducted in Ife Central Local Government Area of Osun State. Data were collected through a household survey using a multi-stage sampling procedure from children between six months and 12 years. Details of each child's socio-demographic characteristics, digit sucking habits, caries status and oral health status were collected. The association between digit sucking, caries status and oral hygiene status was determined using Chi square and Logistic regression. The mean age of the 992 study participants was 5.8 ± (3.2) years. The prevalence of digit sucking, caries and poor oral hygiene were 7.2%, 10.5% and 2.4% respectively. The mean dmft score was 0.22 ± (0.80), mean DMFT score was 0.04 ± (0.30) while mean Oral Hygiene Index score was 1.27 ± (0.73). Digit sucking increased the odds of having caries (OR: 1.28; CI: 0.58-2.81) but decreased the odds of having poor oral hygiene (OR: 0.58; CI: 0.34-1.01) insignificantly. Digit sucking was not a significant predictor of caries and oral hygiene status, although the odds of having caries increased while the odds of having poor oral hygiene decreased with digit sucking.

  3. Gestational Vitamin 25(OHD Status as a Risk Factor for Receptive Language Development: A 24-Month, Longitudinal, Observational Study

    Directory of Open Access Journals (Sweden)

    Frances A. Tylavsky

    2015-12-01

    Full Text Available Emerging data suggest that vitamin D status during childhood and adolescence can affect neurocognitive development. The purpose of this study was to investigate whether gestational 25(OHD status is associated with early childhood cognitive and receptive language development. The Conditions Affecting Neurocognitive Development and Learning in Early Childhood Study (CANDLE study enrolled 1503 mother-child dyads during the second trimester of healthy singleton pregnancies from Shelby County TN. Among 1020 participants of the total CANDLE cohort for whom 25(OHD levels were available, mean gestational 25(OHD level during the second trimester was 22.3 ng/mL (range 5.9–68.4, with 41.7% of values <20 ng/dL. Cognitive and language scaled scores increased in a stair-step manner as gestational 25(OHD levels in the second trimester rose from <20 ng/dL, through 20–29.99 ng/dL, to ≥30 ng/dL. When controlling for socioeconomic status, race, use of tobacco products, gestational age of the child at birth, and age at the 2-year assessment, the gestational 25(OHD was positively related to receptive language development (p < 0.017, but not cognitive or expressive language.

  4. Progress and status of the integral fast reactor (IFR) development program

    International Nuclear Information System (INIS)

    Chang, Y.I.

    1992-01-01

    This paper discusses the Integral Fast Reactor (IFR) development program, in which the entire reactor system - reactor, fuel cycle, and waste process is being developed and optimized at the same time as a single integral entity. Detailed discussions on the present status of the IFR technology development activities in the areas of fuels, pyroprocessing, safety, core design, and fuel cycle demonstration are also presented

  5. Incidence of infection in 39-month-old ewes with TMEM154 diplotypes "1 1," "1 3," and "3 3" after natural exposure to ovine progressive pneumonia virus.

    Science.gov (United States)

    Leymaster, K A; Chitko-McKown, C G; Heaton, M P

    2015-01-01

    Production and well-being of sheep and goats in many countries are harmfully impacted by small ruminant lentiviruses (SRLV) that cause incurable, progressive diseases. Susceptibility to ovine progressive pneumonia virus (OPPV), the North American form of SRLV, is influenced by variants of the ovine transmembrane protein 154 gene (TMEM154). The experimental objective was to estimate additive and dominance effects of TMEM154 haplotypes 1 and 3 on susceptibility of breeding ewes to infection after natural exposure to OPPV from birth to 39 mo of age. Sires and dams were heterozygous for TMEM154 haplotypes 1 and 3, producing ewe lambs with diplotypes "1 1," "1 3," and "3 3." These lambs were raised by mature, infected dams to ensure natural, maternal exposure to OPPV. Ewe lambs (n = 108) were kept for breeding and joined an infected flock of ewes to guarantee natural, nonmaternal exposure to OPPV. Ewes were bred to lamb at 1, 2, and 3 yr of age. Serum samples were collected at breeding, 1 mo before lambing and shortly after weaning each year to monitor infection status to 39 mo of age. During the experiment, 9 of the 108 ewes died while uninfected and data collected on these ewes were not analyzed. Infection status of the remaining 99 ewes at 39 mo of age was analyzed using logistic regression procedures. Effects of ewe type of birth, ewe type of rearing, and breed type of dam were not detected (P > 0.10), and the estimated sire variance component was nil. Ewe diplotype affected infection status (P ewes with diplotypes "1 1," "1 3," and "3 3" were 0.10, 0.88, and 0.89, respectively, and confidence intervals for diplotypes "1 3" and "3 3" were distinct from "1 1." Haplotype 3 was completely dominant to haplotype 1 at 39 mo of age. The probability of infection for ewes with either diplotype "1 3" or "3 3" averaged 8.5 times that of ewes with diplotype "1 1." Diplotype "1 3" and "3 3" ewes were highly susceptible to nonmaternal transmission of OPPV, in contrast to

  6. Revised management plan, milestone plan, cost plan, and manpower plan. Sixth and seventh monthly status reports, October 1-November 30, 1978

    Energy Technology Data Exchange (ETDEWEB)

    None,

    1978-01-01

    The following are included: project background and discussion, technical progress reports for all subtasks, contract management summary report, milestone schedule and status report, milestone log, cost plans, cost management reports, manpower plans, and manpower management reports. The following appendices are included: selection of heat pumps simulation locations, economic computations, fuel costs, system studies, recommended methodology for calculating residential load models, potential performance of heat pumps, data required from cooling contractors, cooling locations, thermal outputs: cooling, recommended inputs for the 25 ton advanced cooling simulation study, meteorological data, and contract modification. (MHR)

  7. Assessment of iron status among preschool children (6 to 59 months) with and without malaria in Western Province, Kenya

    Science.gov (United States)

    Kisiangani, Isaac; Mbakaya, Charles; Makokha, Anzelimo; Magu, Dennis

    2015-01-01

    Introduction Iron deficiency is a major public health concern. Globally, iron deficiency ranks number 9 and is responsible for about 60% of all anemia cases among preschool children. In Africa iron deficiency is 43-52% while in Kenya, children under 5 years constitute the largest burden with 69% of them being deficient. There is limited iron deficiency data in Kenya. This study determined haemoglobin levels, serum ferritin levels, nutritional status and P.falciparum malaria infection in preschool children. Methods A household cross sectional study was undertaken among 125 preschoolers in Western province, drawn from 37 clusters. Systematic random sampling was used for sample selection. Data was collected using pretested structured questionnaires, entered in Microsoft package. Data analysis was done in Statistical package for social science (SPSS) version 20 using bivariate and multivariate logistic regression and differences were considered significant at P iron deficiency (Serum ferritin iron deficiency and anaemia (OR = 3.43, 95% CI: 1.33-8.84, p = 0.008). A preschool child with anaemia was 3.43 times likely to be iron deficient compared to a preschool child who was not anaemic. Conclusion Iron deficiency, anaemia and plasmodium falciparum malaria was prevalent among preschool children. The findings revealed a significant association between iron deficiency and anaemia. Therefore effective interventions to improve iron status will have large health benefits by greatly reducing anaemia in preschool children. PMID:26405498

  8. Present status of refining and conversion facility dismantling. Progress in first half of 2010FY

    International Nuclear Information System (INIS)

    Kado, Kazumi; Sugitsue, Noritake; Morimoto, Yasuyuki; Ikegami, Sohei; Tanaka, Yoshio; Takahashi, Nobuo; Tokuyasu, Takashi

    2011-06-01

    The Refining and Conversion Facility located in the Ningyo-toge Environmental Engineering Center had the natural uranium conversion process and reprocessed uranium conversion process. The construction of this facility was started in 1979 and completed in October 1981. Dismantling of equipments in radiation controlled area of this facility was started from 2008, and all equipments in radiation controlled area will be dismantled by the 2011 fiscal year. This report describes the master plan of this decommissioning and shows as the progress in first half year of 2010FY, the actual time schedule, the method of decommissioning, the decommissioning progress appearance with photographs, work rates of each room / each worker class, and the quantity of dismantled materials and secondary wastes. (author)

  9. Present status of refining and conversion facility dismantling. Progress in latter half of 2010FY

    International Nuclear Information System (INIS)

    Kado, Kazumi; Sugitsue, Noritake; Morimoto, Yasuyuki; Ikegami, Sohei; Tanaka, Yoshio; Takahashi, Nobuo; Tokuyasu, Takashi

    2011-09-01

    The Refining and Conversion Facility located in the Ningyo-toge Environmental Engineering Center had the natural uranium conversion process and reprocessed uranium conversion process. The construction of this facility was started in 1979 and completed in October 1981. Dismantling of equipments in radiation controlled area of this facility was started from 2008. Equipments in radiation controlled area (excluding ventilating equipment and liquid waste treatment equipment) will be dismantled by the 2011 fiscal year, and ventilating equipment and liquid waste treatment equipment will be dismantled by the 2014 fiscal year. This report describes the master plan of this decommissioning and shows as the progress in latter half year of 2010FY, the actual time schedule, the method of decommissioning, the decommissioning progress appearance with photographs, work rates of each room / each worker class, and the quantity of dismantled materials and secondary wastes. (author)

  10. Present status of refining and conversion facility dismantling. Progress in first half of 2009FY

    International Nuclear Information System (INIS)

    Kado, Kazumi; Sugitsue, Noritake; Morimoto, Yasuyuki; Ikegami, Sohei; Tanaka, Yoshio; Takahashi, Nobuo; Tokuyasu, Takashi

    2010-03-01

    The Refining and Conversion Facility located in the Ningyo-toge Environmental Engineering Center had the natural uranium conversion process and reprocessed uranium conversion process. The construction of this facility was started in 1979 and completed in October 1981. Dismantling of equipments in radiation controlled area of this facility was started from 2008, and all equipments in radiation controlled area will be dismantled by the 2011 fiscal year. This report describes the master plan of this decommissioning and shows as the progress in first half year of 2009FY, the actual time schedule, the method of decommissioning, the decommissioning progress appearance with photographs, work rates of each room / each worker class, and the quantity of dismantled materials and secondary wastes. (author)

  11. Present status of refining and conversion facility dismantling. Progress in latter half of 2008FY

    International Nuclear Information System (INIS)

    Kado, Kazumi; Sugitsue, Noritake; Morimoto, Yasuyuki; Ikegami, Sohei; Takahashi, Nobuo; Tokuyasu, Takashi

    2010-01-01

    The Refining and Conversion Facility located in the Ningyo-toge Environmental Engineering Center had the natural uranium conversion process and reprocessed uranium conversion process. The construction of this facility was started in 1979 and completed in October 1981. Dismantling of equipments in radiation controlled area of this facility was started from 2008, and all equipments in radiation controlled area will be dismantled by the 2011 fiscal year. This report describes the master plan of this decommissioning and shows as the progress in latter half year of 2008FY, the actual time schedule, the method of decommissioning, the decommissioning progress appearance with photographs, work rates of each room/each worker class, and the quantity of dismantled materials and secondary wastes. (author)

  12. Are morphologic and functional consequences of status epilepticus in infant rats progressive?

    Czech Academy of Sciences Publication Activity Database

    Kubová, Hana; Mareš, Pavel

    2013-01-01

    Roč. 235, APR 3 (2013), s. 232-249 ISSN 0306-4522 R&D Projects: GA ČR(CZ) GAP302/10/0971; GA ČR(CZ) GBP304/12/G069; GA MŠk(CZ) ME08045 Institutional research plan: CEZ:AV0Z50110509 Institutional support: RVO:67985823 Keywords : status epilepticus * immature brain * brain atrophy * epilepsy * cognitive impairment Subject RIV: FH - Neurology Impact factor: 3.327, year: 2013

  13. Nuclear safeguards research. Program status report. Progress report, September--December 1975

    International Nuclear Information System (INIS)

    1976-04-01

    This report presents the status of the Nondestructive Assay R and D program of the LASL Nuclear Safeguards Research Group, R-1, covering the period September-December 1975. It covers: holdup measurements at the Kerr-McGee Pu facility at Crescent, Okla.; calculations for Random Driver; instrument development and measurement controls; ERDA nondestructive assay training program; and in-plant dynamic materials control (DYMAC) program. 22 figures, 5 tables

  14. Development of incident progress prediction technologies for nuclear emergency preparedness. Current status and future subjects

    International Nuclear Information System (INIS)

    Yoshida, Yoshitaka; Yamamoto, Yasunori; Kusunoki, Takayoshi; Kawasaki, Ikuo; Yanagi, Chihiro; Kinoshita, Ikuo; Iwasaki, Yoshito

    2014-01-01

    Nuclear licensees are required to maintain a prediction system during normal condition for using a nuclear emergency by the Basic Plan for Disaster Prevention of government. With prediction of the incident progress, if the present condition of nuclear power plant is understood appropriately and it grows more serious with keeping the present situation, it is in predicting what kind of situation will be occurred in the near future, choosing the effective countermeasures against the coming threat, and understanding the time available of intervention time. Following the accident on September 30 1999 in the nuclear fuel fabrication facility in Tokai Village of Ibaraki Prefecture, the Institute of Nuclear Safety System started development of incident progress prediction technologies for nuclear emergency preparedness. We have performed technical applications and made improvements in nuclear emergency exercises and verified the developed systems using the observed values of the Fukushima Daiichi Nuclear Power Plant accident. As a result, our developed Incident Progress Prediction System was applied to nuclear emergency exercises and we accumulated knowledge and experience by which we improved the system to make predictions more rapidly and more precisely, including for example, the development of a prediction method for leak size of reactor coolant. On the other hand, if a rapidly progressing incident occurs, since end users need simple and quick predictions about the public's protection and evacuation areas, we developed the Radioactive Materials Release, Radiation Dose and Radiological Protection Area Prediction System which changed solving an inverse problem into a forward problem solution. In view of the water-level-decline incident of the spent fuel storage facility at the Fukushima Daiichi Nuclear Power Plant, the spent fuel storage facility water level and the water temperature evaluation tool were improved. Such incident progress prediction technologies were

  15. HbA1C variability and the risk of renal status progression in Diabetes Mellitus: a meta-analysis.

    Directory of Open Access Journals (Sweden)

    Dongsheng Cheng

    Full Text Available To explore the association between glycated hemoglobin (A1C variability and renal disease progression in patients with diabetes mellitus.A comprehensive search was performed using the PubMed and Embase databases (up to April 26, 2014. The hazard ratio (HR was pooled per unit increase in the standard deviation of A1C (A1C-SD to evaluate the dose-response relationship between A1C-SD and the risk of nephropathy.Eight studies with a total of 17,758 subjects provided the HR for A1C-SD and were included in the final meta-analysis. The pooled HR results demonstrated that A1C-SD was significantly associated with the progression of renal status (HR for both T1DM and T2DM 1.43, 95% confidence interval [CI] 1.24-1.64; HR for T1DM 1.70, 95%CI 1.41-2.05; HR for T2DM 1.20, 95%CI 1.12-1.28. A1C-SD was significantly correlated with new-onset microalbuminuria (HR for T1DM 1.63, 95%CI 1.28-2.07; HR for T2DM 1.23, 95%CI 1.08-1.39. These outcomes were also supported in subgroup analyses. Furthermore, sensitivity analyses demonstrated that the results were robust.A1C variability is independently associated with the development of microalbuminuria and the progression of renal status in both type 1 and 2 diabetes patients. A standard method for measuring A1C variability is essential for further and deeper analyses. In addition, future studies should assess the effect of reducing A1C variability on nephropathy complication.

  16. Focal status epilepticus and progressive dyskinesia: A novel phenotype for glycine receptor antibody-mediated neurological disease in children.

    Science.gov (United States)

    Chan, D W S; Thomas, T; Lim, M; Ling, S; Woodhall, M; Vincent, A

    2017-03-01

    Antibody-associated disorders of the central nervous system are increasingly recognised in adults and children. Some are known to be paraneoplastic, whereas in others an infective trigger is postulated. They include disorders associated with antibodies to N-methyl-d-aspartate receptor (NMDAR), voltage-gated potassium channel-complexes (VGKC-complex), GABA B receptor or glycine receptor (GlyR). With antibodies to NMDAR or VGKC-complexes, distinct clinical patterns are well characterised, but as more antibodies are discovered, the spectra of associated disorders are evolving. GlyR antibodies have been detected in patients with progressive encephalopathy with rigidity and myoclonus (PERM), or stiff man syndrome, both rare but disabling conditions. We report a case of a young child with focal seizures and progressive dyskinesia in whom GlyR antibodies were detected. Anticonvulsants and immunotherapy were effective in treating both the seizures and movement disorder with good neurological outcome and with a decline in the patient's serum GlyR-Ab titres. Glycine receptor antibodies are associated with focal status epilepticus and seizures, encephalopathy and progressive dyskinesia and should be evaluated in autoimmune encephalitis. Copyright © 2016 European Paediatric Neurology Society. Published by Elsevier Ltd. All rights reserved.

  17. Nutritional Status and Its Related Factors among 6-24 Month-Old Children Referring to Health Care Centers in Arsanjan City, Southern Iran

    Directory of Open Access Journals (Sweden)

    Shiva Faghih

    2016-12-01

    Full Text Available Background: Considering that children are major part of most populations and also considering the fact that childhood nutrition affects the health status in adulthood, we aimed to assess the nutritional status and its related factors among 6-24-month-old children referring to health care centers in Arsanjan city, southern Iran, in 2011. Methods: This cross-sectional study was done on 310 children aged 6-24 months. Weight and height were measured and data regarding demographic status, type of feeding, and birth order, were gathered by face to face interview with mothers of the children. Exact age of the children was recorded according to their birth certificate. Z-scores of weight and height were calculated using Epi-info software. SPSS version 16 was used for data analysis. Results: 27.2% of the studied children were mildly underweight, 2-6% were moderately underweight, and 0.3% were severely underweight. Also 15.6%, 1.6%, and 0.3% had mild, moderate, and severe stunting, respectively. According to weight for age index 7.4% were mildly overweight and 1.6% were moderately overweight. The prevalence of underweight was significantly more among 6-month-old children compared with the older children (P=0.019. There were no correlations between underweight and stunting and parents’ education or breast feeding. Conclusion: Our results indicated that although the prevalence of malnutrition is less than previous decade, it is still substantial. On the other hand it seems that the prevalence of overweight among children younger than 2 years is increasing. As childhood obesity is a risk factor for adulthood obesity and its related diseases such as diabetes and cardiovascular diseases, prevention of obesity among children is of importance.

  18. Facility status and progress of the INEL's WERF MLLW and LLW incinerator

    International Nuclear Information System (INIS)

    Conley, D.; Corrigan, S.

    1996-01-01

    The Idaho National Engineering Laboratory's (INEL) Waste Experimental Reduction Facility (WERF) incinerator began processing beta/gamma- emitting low-level waste (LLW) in September 1984. A Resource Conservation and Recovery Act (RCRA) trial burn for the WERF incinerator was conducted in 1986, and in 1989 WERF began processing (hazardous and low-level radioactive) waste known as mixed low-level waste (MLLW). On February 14, 1991 WERF operations were suspended to improve operating procedures and configuration management. On July 12, 1995, WERF initiated incineration of LLW; and on September 20, 1995 WERF resumed its primary mission of incinerating MLLW. MLLW incineration is proceeding under RCRA interim status. State of Idaho issuance of the Part B permit is one of the State's highest permitting priorities. The State of Idaho's Division of Environmental Quality is reviewing the permit application along with a revised trial burn plan that was also submitted with the application. The trial burn has been proposed to be performed in 1996 to demonstrate compliance with the current incinerator guidance. This paper describes the experiences and problems associated with WERF's operations, incineration of MLLW, and the RCRA Part B Permit Application. Some of the challenges that have been overcome include waste characterization, waste repackaging, repackaged waste storage, and implementation of RCRA interim status requirements. A number of challenges remain. They include revision of the RCRA Part B Permit Application and the Trial Burn Plan in response to comments from the state permit application reviewers as well as facility and equipment upgrades required to meet RCRA Permitted Status

  19. Progress and status of the Integral Fast Reactor (IFR) development program

    International Nuclear Information System (INIS)

    Chang, Yoon I.

    1992-01-01

    In the Integral Fast Reactor (IFR) development program, the entire reactor system -- reactor, fuel cycle, and waste process is being developed and optimized at the same time as a single integral entity. The ALMR reactor plant design is being developed by an industrial team headed by General Electric and is presented in a companion paper. Detailed discussions on the present status of the IFR technology development activities in the areas of fuels, pyroprocessing, safety, core design, and fuel cycle demonstration are presented in the other two companion papers that follows this

  20. Progress and status of the Integral Fast Reactor (IFR) development program

    Energy Technology Data Exchange (ETDEWEB)

    Chang, Yoon I.

    1992-04-01

    In the Integral Fast Reactor (IFR) development program, the entire reactor system -- reactor, fuel cycle, and waste process is being developed and optimized at the same time as a single integral entity. The ALMR reactor plant design is being developed by an industrial team headed by General Electric and is presented in a companion paper. Detailed discussions on the present status of the IFR technology development activities in the areas of fuels, pyroprocessing, safety, core design, and fuel cycle demonstration are presented in the other two companion papers that follows this.

  1. Progress and status of the Integral Fast Reactor (IFR) development program

    Energy Technology Data Exchange (ETDEWEB)

    Chang, Yoon I.

    1992-01-01

    In the Integral Fast Reactor (IFR) development program, the entire reactor system -- reactor, fuel cycle, and waste process is being developed and optimized at the same time as a single integral entity. The ALMR reactor plant design is being developed by an industrial team headed by General Electric and is presented in a companion paper. Detailed discussions on the present status of the IFR technology development activities in the areas of fuels, pyroprocessing, safety, core design, and fuel cycle demonstration are presented in the other two companion papers that follows this.

  2. Nutritional status, exclusive breastfeeding and management of acute respiratory illness and diarrhea in the first 6 months of life in infants from two regions of Indonesia.

    Science.gov (United States)

    Oktaria, V; Lee, K J; Bines, J E; Watts, E; Satria, C D; Atthobari, J; Nirwati, H; Kirkwood, C D; Soenarto, Y; Danchin, M H

    2017-12-21

    Infant morbidity and mortality rates remain high in Indonesia, with acute respiratory illnesses (ARI) and diarrhea the leading two health problems in children under 5 years. We aimed to describe the nutritional status, feeding practice and case management of ARI and diarrhea of infants from two regions of Indonesia during the first 6 months of life. This study was an observational study conducted in parallel to an immunogenicity and efficacy trial of an oral rotavirus vaccine (RV3-BB) in the Klaten and Yogyakarta regions, Indonesia. Mothers were interviewed at 3 time points: within the first 6 days of their infant's life, and at 8-10 and 22-24 weeks of age. Questions asked included pregnancy history, infant nutritional status, feeding status and health of infants within up to 2 weeks prior to the assessment. Between February 2013 and January 2014, 233 mother-infant pairs were recruited. 60% (136/223) of infants were exclusively breastfed (EBF) until 6 months of age with the strongest support for EBF reported by mothers themselves 70% (101/223) and 25% (36/223) from their partners. At 6 months, 6% (14/223) of infants were underweight and severely underweight; 4% (8/ 223) wasted and severely wasted; and 12% (28/223) were stunted and severely stunted. Non-recommended medication use was high, with 54% (21/39) of infants with reported cough within 2 weeks of an assessment receiving cough medication, 70% (27 /39) an antihistamine, 26% (10/39) a mucolytic and 15% (6 /39) an oral bronchodilator. At age 22-24 week, infants with reported diarrhea within 2 weeks of an assessment had low use of oral rehydration solutions (ORS) (3/21;14%) and zinc therapy (2/ 21;10%). In this unique observational study, breastfeeding rates of 60% at 6 months were below the Indonesian national target of >75%. Adherence to WHO guidelines for management of ARI and diarrhea was poor, with high use of non-recommended cough medications and oral bronchodilators in the first 6 months of life

  3. Anemia and Micronutrient Status of Women of Childbearing Age and Children 6–59 Months in the Democratic Republic of the Congo

    Directory of Open Access Journals (Sweden)

    Sarah Harvey-Leeson

    2016-02-01

    Full Text Available Little is known about the micronutrient status of women and children in the Democratic Republic of the Congo, which is critical for the design of effective nutrition interventions. We recruited 744 mother-child pairs from South Kivu (SK and Kongo Central (KC. We determined hemoglobin (Hb, serum zinc, vitamin B12, folate, ferritin, soluble transferrin receptor (sTfR, retinol binding protein (RBP, C-reactive protein, and α-1 acid glycoprotein concentrations. Anemia prevalence was determined using Hb adjusted for altitude alone and Hb adjusted for both altitude and ethnicity. Anemia prevalence was lower after Hb adjustment for altitude and ethnicity, compared to only altitude, among women (6% vs. 17% in SK; 10% vs. 32% in KC, children 6–23 months (26% vs. 59% in SK; 25% vs. 42% in KC, and children 24–59 months (14% vs. 35% in SK; 23% vs. 44% in KC, respectively. Iron deficiency was seemingly higher with sTfR as compared to inflammation-adjusted ferritin among women (18% vs. 4% in SK; 21% vs. 5% in KC, children 6–23 months (51% vs. 14% in SK; 74% vs. 10% in KC, and children 24–59 months (23% vs. 4% in SK; 58% vs. 1% in KC. Regardless of indicator, iron deficiency anemia (IDA never exceeded 3% in women. In children, IDA reached almost 20% when sTfR was used but was only 10% with ferritin. Folate, B12, and vitamin A (RBP deficiencies were all very low (<5%; RBP was 10% in children. The prevalence of anemia was unexpectedly low. Inflammation-adjusted zinc deficiency was high among women (52% in SK; 58% in KC, children 6–23 months (23% in SK; 20% in KC, and children 24–59 months (25% in SK; 27% in KC. The rate of biochemical zinc deficiency among Congolese women and children requires attention.

  4. Vitamin D status and determinants of deficiency in non-supplemented athletes during the winter months in Tunisia

    Directory of Open Access Journals (Sweden)

    A Sghaier-Ayadi

    2015-11-01

    Full Text Available Recent reports suggest that hypovitaminosis D in athletes is as common as in the general population. This study was devised to examine vitamin D status and determinants of deficiency in athletes living in a sunny country (Tunisia. One hundred and fifty national elite athletes, training outdoors (n=83 or indoors (n=67, were enrolled from January to February 2012. Plasma 25-hydroxyvitamin D was measured by radioimmunoassay. Concentrations were between 50 and 75 nmol · l -1 in 21.3% of participants, between 25 and 50 nmol · l -1 in 55.3% of participants and <25 nmol · l -1 in 14.7% of participants. The concentrations were significantly lower in indoor athletes than outdoor athletes (36.2±19.0 nmol · l -1 vs. 49.1±19.2 nmol · l -1 ; p<0.001. In multivariate analysis, vitamin D deficiency (25-hydroxyvitamin D <50 nmol · l -1 was associated with indoor sports [multi-adjusted odds ratio (95% confidence interval, 5.03 (1.64-15.4; p=0.005], female gender [3.72 (1.44-9.65; p=0.007] and age < 18 years [2.40 (1.01-5.85; p=0.05]. Athletes living in sun-rich environments are exposed to a high risk of vitamin D inadequacy. Given the importance of vitamin D in health and athletic ability, targeting sufficient levels of plasma 25-hydroxyvitamin D in athletes is well justified.

  5. The “New Doctorate” in Austria: Progress toward a Professional Model or Status Quo?

    Directory of Open Access Journals (Sweden)

    Hans Pechar

    2012-01-01

    Full Text Available Until recently, both policy direction and public awareness of the Bologna Process has been focused almost unilaterally on the introduction of the Bachelor’s degree to European universities. This is understandable, as for most European countries, the Bachelor is a new academic degree. However, commencing with the Berlin Ministerial Conference (Realising the European Higher Education Area, 2003, reform of doctoral studies has been highlighted as a second equal pillar in the Bologna reform process. In this paper, we begin by providing an overview of the general policy background and the rationales that underlie the attempts to restructure doctoral studies in Europe. Next, we focus on the specific situation in Austria, where peculiarities of the status quo collide with uniquely Austrian approaches to reforming doctoral education. Finally, through two case studies, we examine initial attempts – and related challenges – to implement the “New Doctorate” in Austria.

  6. CO2 emissions abatement and geologic sequestration - industrial innovations and stakes - status of researches in progress

    International Nuclear Information System (INIS)

    2005-01-01

    This colloquium was jointly organized by the French institute of petroleum (IFP), the French agency of environmental and energy mastery (Ademe) and the geological and mining research office (BRGM). This press kit makes a status of the advances made in CO 2 emissions abatement and geological sequestration: technological advances of CO 2 capture and sequestration, geological reservoir dimensioning with respect to the problem scale, duration of such an interim solution, CO 2 emissions abatement potentialities of geological sequestration, regulatory, economical and financial implications, international stakes of greenhouse gas emissions. This press kit comprises a press release about the IFP-Ademe-BRGM colloquium, a slide presentation about CO 2 abatement and sequestration, and four papers: a joint IFP-Ademe-BRGM press conference, IFP's answers to CO 2 emissions abatement, Ademe's actions in CO 2 abatement and sequestration, and BRGM's experience in CO 2 sequestration and climatic change expertise. (J.S.)

  7. Status and progress of the RERTR program in the year 2002

    International Nuclear Information System (INIS)

    Travelli, A.; Technology Development

    2003-01-01

    Following the cancellation of the 2001 International RERTR Meeting, which had been planned to occur in Bali, Indonesia, this paper describes the progress achieved by the Reduced Enrichment for Research and Test Reactors (RERTR) Program in collaboration with its many international partners during the years 2001 and 2002, and discusses the main activities planned for the year 2003. The past two years have been characterized by very important achievements of the RERTR program, but these technical achievements have been overshadowed by the terrible events of September 11, 2001. Those events have caused the U.S. Government to reevaluate the importance and urgency of the RERTR program goals. A recommendation made at the highest levels of the government calls for an immediate acceleration of the program activities, with the goal of converting all the world's research reactors to low-enriched fuel at the earliest possible time, and including both Soviet-designed and United States-designed research reactors

  8. Nutritional Status and Effect of Maternal Employment among Children Aged 6-59 Months in Wolayta Sodo Town, Southern Ethiopia: A Cross-sectional Study.

    Science.gov (United States)

    Eshete, Hiwot; Abebe, Yewelsew; Loha, Eskindir; Gebru, Teklemichael; Tesheme, Tesfalem

    2017-03-01

    Childhood malnutrition remains common in many parts of the world; the magnitude of worldwide stunting, underweight and wasting in children under five years of age were 24.7 %, 15.1 % and 7.8 %, respectively. More than 150 million children under the age of five years in the developing world are malnourished. Ethiopia is one of the countries in sub-Saharan Africa with the highest rates of malnutrition. In Ethiopia, 44.4% and 9.7% of children under-five years old were stunted and wasted, respectively. This study was aimed to assess nutritional status and effect of maternal employment among children aged 6-59 months. A cross-sectional study was conducted in Wolayta Sodo Town, Southern Ethiopia. Socio-demographic characteristics, child feeding and healthcare seeking practice of mothers, and child's anthropometric status were assessed. Probability proportional to size sampling approach was used to select a sample of 316 mothers having children aged 6-59 months. The study was ethically approved by Institutional Review Board of Health Science College, Hawasa University. The overall result revealed that the prevalence of stunting was 22.2%, of which 21.8% and 22.6% were in children of employed and unemployed mothers, respectively. Low-weight-for age was 10.8% for children of employed mothers and 13.4% for children of unemployed mothers. Wasting was 8.8% and 10.8% for children of employed and unemployed mothers, respectively. There was no statistically significant association between maternal employment and nutritional status of their children. However, chronic malnutrition (stunting) was influenced by being educated mother (OR: 0.37) child age group of 24-59 months (OR: 0.36) and households' fifth wealth quintile (OR: 0.28). Low prevalence of stunting was observed. Stunting is a public health concern in the study area. Furthermore, stunting is significantly influenced by mothers' education, household wealth and child age. However, maternal employment was not statistically

  9. Status and progress of the RERTR program in the year 2000

    International Nuclear Information System (INIS)

    Travelli, Armando

    2000-01-01

    This paper describes the progress achieved by the Reduced Enrichment for Research and Test Reactors (RERTR) Program in collaboration with its many international partners during the year 2000 and discusses the main activities planned for the year 2001. The past year was held by important accomplishments and events for the RERTR program: Four additional shipments containing 503 spent fuel assemblies from foreign research reactors were accepted by the U.S. Altogether, 3,740 spent fuel assemblies from foreign research reactors have been received by the U.S. under the acceptance policy; Postirradiation examinations of three batches of microplates have continued to reveal excellent irradiation behavior of U-Mo dispersion fuels in a variety of compositions and irradiating conditions. Irradiation of two new batches of miniplates of greater sizes is in progress in the ATR to investigate the swelling behavior of these fuels under prototypic conditions. These materials hold the promise of achieving the program goal of developing LEU research reactor fuels with uranium densities in the 8-9 g /cm 3 range; Qualification of the U-Mo dispersion fuels is proceeding on schedule. Test fuel elements with uranium density of 6 g/cm 3 are being fabricated by BWXT and are scheduled to begin undergoing irradiation in the HFR-Petten in the spring of 2001, with a goal of qualifying this fuel by the end of 2003. U-Mo fuel with uranium density of 8-9 g/cm 3 is planned to be qualified by the end of 2005; Joint LEU conversion feasibility studies were completed for HFR-Petten and for SAFARI-1; Significant improvements were made in the design of LEU metal-foil annular targets that would allow efficient production of fission 99 Mo. Irradiations in the RAS-GAS reactor showed that these targets can formed from aluminum tubes, and that the yield and purity of their product from the acidic process were at least as good as those from the HEU Cintichem targets; Progress was made on irradiation testing of

  10. Status and progress of the RERTR program in the year 2000

    International Nuclear Information System (INIS)

    Travelli, A.

    2000-01-01

    This paper describes the progress achieved by the Reduced Enrichment for Research and Test Reactors (RERTR) Program in collaboration with its many international partners during the year 2000 and discusses the main activities planned for the year 2001. The past year was characterized by important accomplishments and events for the RERTR program. Four additional shipments containing 503 spent fuel assemblies from foreign research reactors were accepted by the U.S. Altogether, 3,740 spent fuel assemblies from foreign research reactors have been received by the U.S. under the acceptance policy. Postirradiation examinations of three batches of microplates have continued to reveal excellent irradiation behavior of U-MO dispersion fuels in a variety of compositions and irradiating conditions. h-radiation of two new batches of miniplates of greater sizes is in progress in the ATR to investigate me swelling behavior of these fuels under prototypic conditions. These materials hold the promise of achieving the program goal of developing LEU research reactor fuels with uranium densities in the 8-9 g /cm 3 range. Qualification of the U-MO dispersion fuels is proceeding on schedule. Test fuel elements with 6 gU/cm 3 are being fabricated by BWXT and are scheduled to begin undergoing irradiation in the HFR-Petten in the spring of 2001, with a goal of qualifying this fuel by the end of 2003. U-Mo with 8-9 gU/cm 3 is planned to be qualified by the end of 2005. Joint LEU conversion feasibility studies were completed for HFR-Petten and for SAFARI-1. Significant improvements were made in the design of LEU metal-foil annular targets that would allow efficient production of fission 99 Mo. Irradiations in the RAS-GAS reactor showed that these targets can formed from aluminum tubes, and that the yield and purity of their product from the acidic process were at least as good as those from the HEU Cintichem targets. Progress was made on irradiation testing of LEU UO 2 dispersion fuel and on

  11. Status and progress of the RERTR program in the year 2002

    International Nuclear Information System (INIS)

    Travelli, Armando

    2002-01-01

    Following the cancellation of the 2001 International RERTR Meeting, which had been planned to occur in Bali, Indonesia, this paper describes the progress achieved by the Reduced Enrichment for Research and Test Reactors (RERTR) Program in collaboration with its many international partners during the years 2001 and 2002, and discusses the main activities planned for the year 2003. The past two years have been characterized by very important achievements of the RERTR program, but these technical achievements have been overshadowed by the terrible events of September 11, 2001. Those events have caused the U.S. Government to reevaluate the importance and urgency of the RERTR program goals. A recommendation made at the highest levels of the government calls for an immediate acceleration of the program activities, with the goal of converting all the world's research reactors to low-enriched fuel at the earliest possible time, and including both Soviet-designed and United States-designed research reactors. The RERTR program has prepared and submitted to the Department of Energy a plan and a schedule to achieve this goal. The plan makes full use of two very important technical developments that have occurred within the program during the past two years: - Excellent results have been obtained from the irradiation of miniplates containing monolithic LEU U-Mo fuel with uranium density of 15.6 g/cm 3 . If an economically viable manner of fabricating monolithic LEU U-Mo fuel elements is developed, and if the preliminary irradiation tests are confirmed, this fuel holds the promise of enabling LEU operation of all existing and future research reactors in combination with unprecedented performance. - The progress achieved within the Russian RERTR program, both for the traditional tube-type elements and for the new 'universal' LEU U-Mo pin-type elements, promises to enable soon the conversion of most Russian-designed research and test reactors. The plan is structured to achieve LEU

  12. Decadal Vision Progress Report Implementation Plans and Status for the Next Generation ARM Facility

    Energy Technology Data Exchange (ETDEWEB)

    Mather, James

    2016-06-01

    The reconfiguration of the ARM facility, formally initiated in early 2014, is geared toward implementing the Next Generation of the ARM Facility, which will more tightly link ARM measurements and atmospheric models. The strategy is outlined in the ARM Climate Research Facility Decadal Vision (DOE 2014a). The strategy includes the implementation of a high-resolution model, initially at the Southern Great Plains (SGP) site, and enhancements at the SGP and North Slope of Alaska (NSA) sites to provide additional observations to support modeling and process studies. Enhancements at the SGP site focus on ground-based instruments while enhancements at the NSA make use of Unmanned Aerial Systems (UAS) and Tethered Balloon Systems (TBS). It is also recognized that new data tools and data products will need to be developed to take full advantage of these improvements. This document provides an update on the status of these ARM facility enhancements, beginning with the measurement enhancements at the SGP and NSA, followed by a discussion of the modeling project including associated data-processing activities.

  13. Progress and status of the international project on innovative nuclear reactors and fuel cycles (INPRO) - 5182

    International Nuclear Information System (INIS)

    Ponomarev, A.; Fesenko, G.; Grigoriev, F.G.; Korinny, A.; Phillips, J.R.; Rho, K.

    2015-01-01

    The IAEA's International Project on Innovative Nuclear Reactors and Fuel Cycles (INPRO) was established in 2000 through IAEA General Conference resolution. INPRO cooperates with Member States to ensure that sustainable nuclear energy is available to help meet the energy needs of the 21. century. INPRO membership has grown to 41 members and 16 observers. The paper presents the current prospectus of the INPRO programme and details the most recent achievements in the following 7 projects: 1) the GAINS project (Global Architecture of Innovative Nuclear Energy Systems with thermal and fast reactors and a closed nuclear fuel cycle); 2) the SYNERGIES project applies and amends the analytical framework developed in GAINS project to examine more specifically the various forms of regional collaboration among nuclear energy suppliers and users; 3) the KIND project (Key Indicators for Innovative Nuclear Energy Systems) has the objective of developing guidance on the evaluation on innovative nuclear technologies; 4) the ROADMAPS project addresses several possible stages toward nuclear energy sustainability; 5) the RISC project aims at demonstrating that the evolution of safety requirements and technical innovations provide continual progress towards the avoidance of evacuation measures outside NPP sites in case of severe accidents; 6) the FANES project has the objective of carrying out feasibility analyses of advanced and innovative fuels for different reactor systems; and 7) the WIRAF project aims at identifying problematic waste from innovative reactor designs and corresponding nuclear fuel cycles

  14. European collaboration for improved monitoring of Icelandic volcanoes: Status of the FUTUREVOLC project after the initial 18 months

    Science.gov (United States)

    Dumont, Stéphanie; Parks, Michelle; Sigmundsson, Freysteinn; Vogfjörð, Kristín; Einarsdóttir, Heiðveig Maria; Tumi Gudmundsson, Magnús; Kristinsson, Ingvar; Loughlin, Sue; Ilyinskaya, Evgenia; Hooper, Andrew; Kylling, Arve; Witham, Claire; Bean, Chris; Braiden, Aoife; Ripepe, Maurizio; Prata, Fred; Pétur Heiðarsson, Einar; Other Members Of The Futurevolc Team

    2014-05-01

    The FUTUREVOLC project funded by the European Union (FP7) is devoted to volcanic hazard assessment and establishing an integrated volcanological monitoring procedure through a European collaboration. To reach these objectives the project combines broad expertise from 26 partners from 10 countries, focusing on the four most active volcanoes of Iceland: Grímsvötn, Katla, Hekla and Bárdarbunga. The geological setting of Iceland, the high rate of eruptions and the various eruption styles make this country an optimal natural laboratory to study volcanic processes from crustal depths to the atmosphere. The project, which began on 1 October 2012, integrates advanced monitoring and analytical techniques in an innovative way, focusing on (i) detailed monitoring to improve our understanding of the seismic/magmatic unrest, in order to estimate the amount of magma available for an eruption and to provide early warnings (ii) the dynamics of magma in the conduit and a near real time estimation of the mass eruption rate and (iii) observing and modelling the plume dynamics. The project design considers effective collaboration between partners and aims for efficient cross-disciplinary workflows. A major step during the first 18 months of the project was the installation of additional equipment in the volcanic regions of Iceland to reinforce and complement the existing monitoring. The instruments include: seismometers, GPS stations, MultigGAS detectors, DOAS, infrasonic arrays, electric field sensors, radars, and optical particle sizers. Data streaming is designed to withstand extreme weather conditions. The FUTUREVOLC project has an open data policy for real and near-time data. Implementation of a data hub is currently under way, based on open access to data from the 2010 Eyjafjallajökull eruption. Access to volcano monitoring data through a common interface will allow timely information on magma movements facilitated through combined analysis. A key part of the project is to

  15. Vitamin D status is associated with underweight and stunting in children aged 6-36 months residing in the Ecuadorian Andes.

    Science.gov (United States)

    Mokhtar, Rana R; Holick, Michael F; Sempértegui, Fernando; Griffiths, Jeffrey K; Estrella, Bertha; Moore, Lynn L; Fox, Matthew P; Hamer, Davidson H

    2017-11-22

    There is limited knowledge on vitamin D status of children residing in the Andes and its association with undernutrition. We evaluated the vitamin D status of children residing in a low socio-economic status (SES) setting in the Ecuadorian Andes and assessed the association between vitamin D status, stunting and underweight. We hypothesized that children who were underweight would have lower serum 25-hydroxyvitamin D (25(OH)D) levels and lower 25(OH)D levels would be associated with a higher risk of stunting. We conducted a cross-sectional secondary analysis of a randomized controlled trial, the Vitamin A, Zinc and Pneumonia study. Children had serum 25(OH)D concentrations measured. A sensitivity analysis was undertaken to determine a vitamin D cut-off specific for our endpoints. Associations between serum 25(OH)D and underweight (defined as weight-for-age Z-score≤-1) and stunting (defined as height-for-age Z-score≤-2) were assessed using multivariate logistic regression. Children residing in five low-SES peri-urban neighbourhoods near Quito, Ecuador. Children (n 516) aged 6-36 months. Mean serum 25(OH)D concentration was 58·0 (sd 17·7) nmol/l. Sensitivity analysis revealed an undernutrition-specific 25(OH)D cut-off of DDD levels were more likely to be stunted (aOR=2·8; 95 % CI 1·6, 4·7). Low serum 25(OH)D levels were more common in underweight and stunted Ecuadorian children.

  16. Status of Dalat research reactor and progress of new reactor plan in Vietnam

    International Nuclear Information System (INIS)

    Dien, Nguyen Nhi; Vien, Luong Ba

    2005-01-01

    The Dalat Nuclear Research Reactor (DNRR) is a 500-kW pool-type reactor loaded with the Soviet WWR-M2 Fuel Assemblies (FA), moderated and cooled by light water. The reactor was reconstructed from the USA 250-kW TRIGA Mark-II reactor built in early 1960s. The first criticality of the renovated reactor was achieved on 1 st November 1983, and then on 20 March 1984 the reactor was officially inaugurated and its activities restarted. During the last twenty years, the DNRR has played an important role as a large national research facility to implement researches and applications, and its utilization has been broadened in various fields of human life. However, due to the limitation of the neutron flux and power level, the out-of date design of the experimental facilities and the ageing of the reactor facilities, it cannot meet the increasing user's demands even in the existing utilization areas. In addition, the utilization demands of the Research Reactor (RR) will be increased along with the development of the nation's economy growth. In this aspect, it is necessary to have in Vietnam a new high performance multipurpose RR with a sufficient neutron flux and power level. According to the last draft of a national strategy for atomic energy development submitted to the Government for consideration and approval, it is expected that a new high power RR would be put into operation before 2020. The operation and utilization status of the DNRR is presented and some preliminary results of the national research project on new reactor plan for Vietnam are discussed in this paper

  17. Current iodine nutrition status and progress toward elimination of iodine deficiency disorders in Jazan, Saudi Arabia

    Directory of Open Access Journals (Sweden)

    Alsanosy Rashad Mohammed

    2012-11-01

    Full Text Available Abstract Background The term iodine deficiency disorders (IDD refers to all the effects of iodine deficiency on growth and development in human and animal populations that can be prevented by correction of the iodine deficiency. The objective of this paper was to determine the iodine nutrition status among schoolchildren in the Jazan Region of the Kingdom of Saudi Arabia (KSA, by measuring urinary iodine concentrations and by clinical assessments of goiter rate. Methods A school-based cross-sectional survey was conducted in the Jazan region of southwestern KSA from May to November 2010. A total of 311 children, aged 6–13 years, drawn from 12 schools, were selected by a three-stage cluster random sampling method. Data on sociodemographic characteristics were collected using a structured questionnaire. Urine samples were collected and physical examinations were conducted to determine the presence or absence of goiter. Data were analyzed using SPSS version 17.0. Chi square and independent t-tests were used for proportions and mean comparisons between groups. Results Out of 360 selected children, 311 were examined. There were 131 males (42% and 180 females (58%. The median urinary iodine concentration (UIC of the study group was 421 μg/L. The study population proportion with UIC > 300 μg/L was 74% with a higher proportion among males and urban populations. The proportion of children with UIC of 100–300 μg/L was only 21% and was significantly higher among females compared with males (p Conclusions The present study demonstrates a remarkable achievement in Universal Salt Iodization (USI and IDD elimination goals in the Jazan area. However, UIC levels reflect excessive iodine intake and may put the population at risk of adverse health consequences like iodine-induced hyperthyroidism and autoimmune thyroid diseases.

  18. Expression status and clinical significance of lncRNA APPAT in the progression of atherosclerosis

    Directory of Open Access Journals (Sweden)

    Fanming Meng

    2018-01-01

    Full Text Available Background Long non-coding RNAs (lncRNAs have been reported to modulate cardiovascular diseases, and expression dynamics of lncRNAs in the bloodstream were proposed to be potential biomarkers for clinical diagnosis. However, few cardiovascular diseases-related circulating lncRNAs were identified and their prediction power has not been investigated in depth. Here we report a new circulating lncRNA, atherosclerotic plaque pathogenesis associated transcript (APPAT, and evaluated its role and predicting ability in atherosclerotic development. Methods APPAT was analyzed and screened by high-throughput sequencing, and then detected in vitro and in vivo. Immunofluorescence-fluorescence in situ hybridization (IF-FISH was utilized to explore distribution and subcellular location of APPAT. The expressing alteration of APPAT in samples of healthy and pathological coronary artery was explored further. We also assessed the level of circulating APPAT in blood samples from healthy individuals, and patients with angina pectoris (AP or myocardial infarction (MI. Additionally, we predicted and validated microRNA targets of APPAT, then showed the expression level of a candidate target which was primarily measured in human VSMCs cell line, coronary artery, and blood samples. Lastly, we examined the potential indicating ability of APPAT for the risk of AP or MI. Results APPAT showed significant reduction in ox-LDL treated human VSMCs in vitro. It enriched in contractile VSMCs of artery tunica media and mainly existed in cytoplasm. Significant down-regulation of APPAT was found in coronary artery samples with severe stenosis. More importantly, we observed decreased expression of APPAT in blood samples accompanying disease progression. ROC and correlation analyses further verified the relatively high predicting ability of APPAT. We also observed the predicted miRNA exhibited opposite expression direction to that of APPAT. Conclusions This study revealed that

  19. Nanoimprint wafer and mask tool progress and status for high volume semiconductor manufacturing

    Science.gov (United States)

    Matsuoka, Yoichi; Seki, Junichi; Nakayama, Takahiro; Nakagawa, Kazuki; Azuma, Hisanobu; Yamamoto, Kiyohito; Sato, Chiaki; Sakai, Fumio; Takabayashi, Yukio; Aghili, Ali; Mizuno, Makoto; Choi, Jin; Jones, Chris E.

    2016-10-01

    Imprint lithography has been shown to be an effective technique for replication of nano-scale features. Jet and Flash* Imprint Lithography (J-FIL*) involves the field-by-field deposition and exposure of a low viscosity resist deposited by jetting technology onto the substrate. The patterned mask is lowered into the fluid which then quickly flows into the relief patterns in the mask by capillary action. Following this filling step, the resist is crosslinked under UV radiation, and then the mask is removed, leaving a patterned resist on the substrate. There are many criteria that determine whether a particular technology is ready for wafer manufacturing. Defectivity and mask life play a significant role relative to meeting the cost of ownership (CoO) requirements in the production of semiconductor devices. Hard particles on a wafer or mask create the possibility of inducing a permanent defect on the mask that can impact device yield and mask life. By using material methods to reduce particle shedding and by introducing an air curtain system, the lifetime of both the master mask and the replica mask can be extended. In this work, we report results that demonstrate a path towards achieving mask lifetimes of better than 1000 wafers. On the mask side, a new replication tool, the FPA-1100 NR2 is introduced. Mask replication is required for nanoimprint lithography (NIL), and criteria that are crucial to the success of a replication platform include both particle control, resolution and image placement accuracy. In this paper we discuss the progress made in both feature resolution and in meeting the image placement specification for replica masks.

  20. Status of Conceptual Design Progress for ITER Sector Sub-assembly Tools

    Energy Technology Data Exchange (ETDEWEB)

    Nam, Kyoung O; Park, Hyun Ki; Kim, Dong Jin [National Fusion Research Institute, Daejeon (Korea, Republic of); Lee, Jae Hyuk; Kim, Kyung Kyu [SFA Engineering Corp., Changwon (Korea, Republic of); Im, Ki Hak; Robert, Shaw [ITER Organization, Paul lez Durance (France)

    2010-05-15

    The ITER (International Thermonuclear Experimental Reactor) Tokamak assembly tools are purpose-built tools to complete the ITER Tokamak machine which includes the cryostat and the components contained therein. Based on the design description document prepared by the ITER organization, Korea has carried out the conceptual design of assembly tools. The 40 .deg. sector assemblies sub-assembled at assembly hall are transferred to Tokamak hall using the lifting tool operated by Tokamak main cranes. In-pit assembly tools are the purpose-built assembly tools for the completion of final sector assembly at Tokamak hall. The 40 .deg. sector sub-assembly tools are composed of the upending tool, the sector sub-assembly tool, the sector lifting tool and the vacuum vessel support and bracing tools. The process of the ITER sector sub-assembly at assembly hall and status of research and development are described in this paper. The ITER Tokamak device is composed of 9 vacuum vessel (VV)/toroidal field coils (TFCs)/vacuum vessel thermal shields (VVTS) 40 .deg. sectors. Each VV/TFCs/VVTS 40 .deg. sector is made up of one 40 .deg. VV, two 20 .deg. TFCs and associated VVTS segments. The 40 .deg. sectors are sub-assembled at assembly hall respectively and then 9 sectors which sub-assembled at assembly hall are finally assembled at Tokamak hall. As a basic assembly component, the assembly strategy and tools for the 40 .deg. sector sub-assembly and final assembly at inpit should be developed to satisfy the basic assembly requirements of the ITER Tokamak device. Accordingly, the purpose-built assembly tools should be designed and manufactured considering assembly plan, available space, safety, easy operation, efficient maintenance, and so on. The 40 .deg. sector assembly tools are classified into 2 groups. One group is the sub-assembly tools including upending tool, lifting tool, sub-assembly tool, VV supports and bracing tools used at assembly hall and the other group is the in

  1. Changes in Bone Mineral Density, Body Composition, Vitamin D Status, and Mineral Metabolism in Urban HIV-Positive South African Women Over 12 Months.

    Science.gov (United States)

    Hamill, Matthew M; Pettifor, John M; Ward, Kate A; Norris, Shane A; Prentice, Ann

    2017-08-01

    Human immunodeficiency virus (HIV) infection and antiretroviral therapy (ART) are associated with bone loss and poor vitamin D status in white populations, though their relative roles are not known. No previous studies have examined longitudinal changes in areal bone mineral density (aBMD), measured by dual-energy X-ray absorptiometry (DXA), or in vitamin D status in HIV-positive African women. Of 247 premenopausal, urban, black African women from Soweto, South Africa, initially recruited, 187 underwent anthropometry, DXA scanning and blood and urine collections at both baseline and 12 months. Of these, 67 were HIV-negative throughout (Nref), 60 were HIV-positive with preserved CD4 counts at baseline (Ppres), and 60 were HIV-positive with low CD4 counts at baseline, eligible for ART by South African standards of care at the time (Plow). No participant had been exposed to ART at baseline. By 12 months, 51 Plow women had initiated ART, >85% of whom took combined tenofovir disoproxil fumarate (TDF), lamivudine, and efavirenz. By 12 months, Plow and Nref, but not Ppres, increased in body weight and fat mass (group-by-timepoint p ≤ 0.001, p = 0.002, respectively). Plow had significant decreases in aBMD of 2% to 3%, before and after size adjustment, at the femoral neck (p ≤ 0.002) and lumbar spine (p ≤ 0.001), despite significant weight gain. These decreases were associated with increased bone turnover but there were no significant differences or changes over time in vitamin D status, serum phosphate concentrations, or renal phosphate handling. Excluding data from nine Plow women unexposed to ART and 11 Ppres women who had initiated ART accentuated these findings, suggesting the bone loss in Plow was related to ART exposure. This is the first study describing DXA-defined bone loss in HIV-positive Sub-Saharan African women in association with ART. Further work is required to establish if bone loss continues with ongoing ART and, if so, whether this

  2. Status and progress of the RERTR program in the year 2003

    International Nuclear Information System (INIS)

    Travelli, Armando

    2003-01-01

    One of the most important events affecting the RERTR program during the past year was the decision by the U.S. Department of Energy to request the U.S. Congress to significantly increase RERTR program funding. This decision was prompted, at least in part, by the terrible events of September 11, 2001, and by a high-level U.S./Russian Joint Expert Group recommendation to immediately accelerate RERTR program activities in both countries, with the goal of converting all the world's research reactors to low-enriched fuel at the earliest possible time, and including both Soviet-designed and United States-designed research reactors. The U.S. Congress is expected to approve this request very soon, and the RERTR program has prepared itself well for the intense activities that the 'Accelerated RERTR Program' will require. Promising results have been obtained in the development of a fabrication process for monolithic LEU U-Mo fuel. Most existing and future research reactors could be converted to LEU with this fuel, which has a uranium density between 15.4 and 16.4 g/cm 3 and yielded promising irradiation results in 2002. The most promising method hinges on producing the monolithic meat by cold-rolling a thin ingot produced by casting. The aluminum clad and the meat are bonded by friction stir welding and the cladding surface is finished by a light cold roll. This method can be applied to the production of miniplates and appears to be extendable to the production of full-size plates, possibly with intermediate anneals. Other methods planned for investigation include high temperature bonding and hot isostatic pressing. The progress achieved within the Russian RERTR program, both for the traditional tube-type elements and for the new 'universal' LEU U-Mo pin-type elements, promises to enable soon the conversion of many Russian-designed research and test reactors. Irradiation testing of both fuel types with LEU U-Mo dispersion fuels has begun. Detailed studies are in progress to

  3. Impacts of Mothers’ Occupation Status and Parenting Styles on Levels of Self-Control, Addiction to Computer Games, and Educational Progress of Adolescents

    OpenAIRE

    Abedini, Yasamin; Zamani, Bibi Eshrat; Kheradmand, Ali; Rajabizadeh, Ghodratollah

    2012-01-01

    Background Addiction to computer (video) games in adolescents and its relationship with educational progress has recently attracted the attention of rearing and education experts as well as organizations and institutes involved in physical and mental health. The current research attempted to propose a structural model of the relationships between parenting styles, mothers’ occupation status, and addiction to computer games, self-control, and educational progress of secondary school students. ...

  4. Infant Development at the Age of 6 Months in Relation to Feeding Practices, Iron Status, and Growth in a Peri-Urban Community of South Africa.

    Science.gov (United States)

    Rothman, Marinel; Faber, Mieke; Covic, Namukolo; Matsungo, Tonderayi M; Cockeran, Marike; Kvalsvig, Jane D; Smuts, Cornelius M

    2018-01-12

    Evidence on the association between feeding practices, iron deficiency, anaemia, stunting, and impaired psychomotor development during infancy is limited. This study assessed the association between psychomotor development with early feeding practices, growth, iron status, and anaemia. This was cross-sectional baseline data of a randomised controlled trial which included 6-month-old infants and their mothers or primary caregivers ( n = 750) in a peri-urban community in the North West province of South Africa. The Kilifi Developmental Inventory and a parent rating scale were used to assess psychomotor development. Feeding practices and anthropometric measurements were based on the World Health Organisation (WHO) guidelines. Anaemia and iron status were determined by blood sample analysis. Prevalence of anaemia and stunting for the infants were 36.4% and 28.5%, respectively. Multiple regression analysis showed that birth weight was related to combined psychomotor scores ( β = -3.427 (-4.603, 1.891), p psychomotor scores ( β = -1.419 (-2.466, 0.373), p = 0.008), as well as parent rating scores ( β = -0.747 (-1.483, -0.010), p = 0.047). In this setting, with high prevalence of anaemia and stunting, important associations between lower psychomotor development scores and birthweight as well as length-for-age z -scores in 6-month-old infants were found. These findings warrant further investigation to develop a greater understanding of factors influencing the association between child growth and psychomotor development within the first 1000 days of life.

  5. Effect of phylloquinone (vitamin K1) supplementation for 12 months on the indices of vitamin K status and bone health in adult patients with Crohn's disease.

    Science.gov (United States)

    O'Connor, Eibhlís M; Grealy, Geraldine; McCarthy, Jane; Desmond, Alan; Craig, Orla; Shanahan, Fergus; Cashman, Kevin D

    2014-10-14

    Although epidemiological findings support a role for vitamin K status in the improvement of bone indices in adult patients with Crohn's disease (CD), this needs to be confirmed in double-blind, randomised controlled trials (RCT) with phylloquinone (vitamin K1). By conducting two RCT, the present study aimed to first establish whether supplementation with 1000 μg of phylloquinone daily near-maximally suppresses the percentage of undercarboxylated osteocalcin in serum (%ucOC; marker of vitamin K status) in adult patients with CD currently in remission as it does in healthy adults and second determine the effect of supplementation with phylloquinone at this dose for 12 months on the indices of bone turnover and bone mass. The initial dose-ranging RCT was conducted in adult patients with CD (n 10 per group) using 0 (placebo), 1000 or 2000 μg of phylloquinone daily for 2 weeks. In the main RCT, the effect of placebo v. 1000 μg vitamin K/d (both co-administered with Ca (500 mg/d) and vitamin D3 (10 μg/d)) for 12 months (n 43 per group) on the biochemical indices of bone turnover (determined by enzyme immunoassay) and bone mass (determined by dual-energy X-ray absorptiometry) were investigated. At baseline, the mean %ucOC was 47 %, and this was suppressed upon supplementation with 1000 μg of phylloquinone daily ( - 81 %; P0·1) on bone turnover markers or on the bone mass of the lumbar spine or femur, but modestly increased (Pvitamin D3) had no effect on the indices of bone health in adult CD patients with likely vitamin K insufficiency.

  6. Fluctuations in Blood Marginal Zone B-Cell Frequencies May Reflect Migratory Patterns Associated with HIV-1 Disease Progression Status.

    Science.gov (United States)

    Gauvin, Julie; Chagnon-Choquet, Josiane; Poudrier, Johanne; Roger, Michel

    2016-01-01

    We have previously shown that overexpression of BLyS/BAFF was associated with increased relative frequencies of innate "precursor" marginal zone (MZ)-like B-cells in the blood of HIV-1-infected rapid and classic progressors. However, along with relatively normal BLyS/BAFF expression levels, these cells remain unaltered in elite-controllers (EC), rather, percentages of more mature MZ-like B-cells are decreased in the blood of these individuals. Fluctuations in frequencies of blood MZ-like B-cell populations may reflect migratory patterns associated with disease progression status, suggesting an important role for these cells in HIV-1 pathogenesis. We have therefore longitudinally measured plasma levels of B-tropic chemokines by ELISA-based technology as well as their ligands by flow-cytometry on blood B-cell populations of HIV-1-infected individuals with different rates of disease progression and uninfected controls. Migration potential of B-cell populations from these individuals were determined by chemotaxis assays. We found important modulations of CXCL13-CXCR5, CXCL12-CXCR4/CXCR7, CCL20-CCR6 and CCL25-CCR9 chemokine-axes and increased cell migration patterns in HIV progressors. Interestingly, frequencies of CCR6 expressing cells were significantly elevated within the precursor MZ-like population, consistent with increased migration in response to CCL20. Although we found little modulation of chemokine-axes in EC, cell migration was greater than that observed for uninfected controls, especially for MZ-like B-cells. Overall the immune response against HIV-1 may involve recruitment of MZ-like B-cells to peripheral sites. Moreover, our findings suggest that "regulated" attraction of these cells in a preserved BLyS/BAFF non-inflammatory environment, such as encountered in EC could be beneficial to the battle and even control of HIV.

  7. Self-reported balance status is not a reliable indicator of balance performance in adolescents at one-month post-concussion.

    Science.gov (United States)

    Rochefort, Coralie; Walters-Stewart, Coren; Aglipay, Mary; Barrowman, Nick; Zemek, Roger; Sveistrup, Heidi

    2017-11-01

    To determine if self-reported balance symptoms can be used as a proxy for measures of the center of pressure (COP) to identify balance deficits in a group of concussed adolescents. Case-control. Thirteen adolescents 1-month post-concussion who reported ongoing balance problems (Balance+), 20 adolescent 1-month post-concussion who reported no balance problems (Balance-), and 30 non-injured adolescents (control) completed a series of balance tests. Participants completed two 2-min trials standing on a Nintendo Wii Balance Board™ during which the COP under their feet was recorded: i) double-leg stance, eyes open; ii) double-leg stance, eyes closed. Participants also completed a dual-task condition combining a double-leg stance and a Stroop Colour-word test. Participants in both the Balance+ and Balance- group swayed over a larger ellipse area compared to the control group while completing the Eyes Closed (Balance+, p=0.002; Balance-, p=0.002) and Dual-Task (Balance+, p=0.001; Balance-, p=0.004) conditions and performed the Dual-Task condition with faster medio-lateral velocity (Balance+, p=0.003; Balance-, p=0.009). The participants in the Balance- group also swayed over a larger ellipse area compared to the control group while completing the Eyes Open condition (p=0.005). No significant differences were identified between the Balance+ and Balance- groups. At 1-month post-concussion, adolescents demonstrated balance deficits compared to non-injured adolescents regardless of whether they reported balance problems. These results suggest that self-reported balance status might not be an accurate reflection of balance performance following a concussion in adolescents. Copyright © 2017 Sports Medicine Australia. Published by Elsevier Ltd. All rights reserved.

  8. So Young and Already Victims of Stereotype Threat: Socio-Economic Status and Performance of 6 to 9 Years Old Children on Raven's Progressive Matrices

    Science.gov (United States)

    Desert, Michel; Preaux, Marie; Jund, Robin

    2009-01-01

    The aim of this study was to verify whether children from low socio-economic status (SES) are victims of stereotype threat. Children in first grade (6 to 7 years old) and third grade (8 to 9 years old) performed Raven's progressive matrices, an intellectual ability test commonly used by psychologists. The test was presented either with the…

  9. Molluscs and echinoderms aquaculture: biological aspects, current status, technical progress and future perspectives for the most promising species in Italy

    Directory of Open Access Journals (Sweden)

    Antonio Pais

    2012-10-01

    Full Text Available Shellfish aquaculture is a widespread activity in the Italian peninsula. However, only two bivalve species are mainly cultured along the coastline of that country: the Mediterranean mussel Mytilus galloprovincialis and the Manila clam Venerupis philippinarum (Ruditapes philippinarum. By contrast, just a few other mollusc species of commercial interest are scarcely reared at a small-scale level. After analysing the current status of Italian shellfish production, this paper reports and discusses the potential for culturing several different invertebrate species [i.e., the European flat oyster Ostrea edulis, the grooved carpet shell Venerupis decussata (Ruditapes decussatus, the razor clams Ensis minor and Solen marginatus, the cephalopod Octopus vulgaris, and the purple sea urchin Paracentrotus lividus] in this country. In addition, a detailed overview of the progress made in aquacultural techniques for these species in the Mediterranean basin is presented, highlighting the most relevant bottlenecks and the way forward to shift from the experimental to the aquaculture phase. Finally, an outlook of the main economic and environmental benefits arising from these shellfish culture practices is also given.

  10. Experimental primates and non-human primate (NHP) models of human diseases in China: current status and progress.

    Science.gov (United States)

    Zhang, Xiao-Liang; Pang, Wei; Hu, Xin-Tian; Li, Jia-Li; Yao, Yong-Gang; Zheng, Yong-Tang

    2014-11-18

    Non-human primates (NHPs) are phylogenetically close to humans, with many similarities in terms of physiology, anatomy, immunology, as well as neurology, all of which make them excellent experimental models for biomedical research. Compared with developed countries in America and Europe, China has relatively rich primate resources and has continually aimed to develop NHPs resources. Currently, China is a leading producer and a major supplier of NHPs on the international market. However, there are some deficiencies in feeding and management that have hampered China's growth in NHP research and materials. Nonetheless, China has recently established a number of primate animal models for human diseases and achieved marked scientific progress on infectious diseases, cardiovascular diseases, endocrine diseases, reproductive diseases, neurological diseases, and ophthalmic diseases, etc. Advances in these fields via NHP models will undoubtedly further promote the development of China's life sciences and pharmaceutical industry, and enhance China's position as a leader in NHP research. This review covers the current status of NHPs in China and other areas, highlighting the latest developments in disease models using NHPs, as well as outlining basic problems and proposing effective countermeasures to better utilize NHP resources and further foster NHP research in China.

  11. Incidence of infection in 39-month-old ewes with TMEM154 diplotypes "1 1," "1 3," and "3 3" after natural exposure to ovine progressive pneumonia virus

    Science.gov (United States)

    Production and well-being of sheep and goats in many countries are harmfully impacted by small ruminant lentiviruses (SRLV) that cause incurable, progressive diseases. Susceptibility to ovine progressive pneumonia virus (OPPV), the North American form of SRLV, is influenced by variants of the ovine...

  12. Incremental Innovation and Progress in Advanced Squamous Cell Lung Cancer: Current Status and Future Impact of Treatment.

    Science.gov (United States)

    Langer, Corey J; Obasaju, Coleman; Bunn, Paul; Bonomi, Philip; Gandara, David; Hirsch, Fred R; Kim, Edward S; Natale, Ronald B; Novello, Silvia; Paz-Ares, Luis; Pérol, Maurice; Reck, Martin; Ramalingam, Suresh S; Reynolds, Craig H; Socinski, Mark A; Spigel, David R; Wakelee, Heather; Mayo, Carlos; Thatcher, Nick

    2016-12-01

    Squamous cell lung cancer (sqCLC) is an aggressive form of cancer that poses many therapeutic challenges. Patients tend to be older, present at a later stage, and have a high incidence of comorbidities, which can compromise treatment delivery and exacerbate toxicity. In addition, certain agents routinely available for nonsquamous cell histologic subtypes, such as bevacizumab and pemetrexed, are contraindicated or lack efficacy in sqCLC. Therapeutic progress has been much slower for advanced sqCLC, with median survival times of approximately 9 to 11 months in most studies. Herein, we discuss the current therapeutic landscape for patients with sqCLC versus with nonsquamous NSCLC. Current evidence indicates that new targeted treatments, notably monoclonal antibodies such as ramucirumab and necitumumab, and immunotherapies such as nivolumab and pembrolizumab can provide survival prolongation, although the benefits are still relatively modest. These incremental improvements, all realized since 2012, in aggregate, will very likely have a clinically meaningful impact for patients with sqCLC. We also discuss recent genomic studies of sqCLC that have identified potentially actionable molecular targets, as well as the relevant targeted agents in clinical development. Finally, we discuss the magnitude of survival benefit and the risk-to-benefit ratio that would prove clinically meaningful in this underserved patient population with unmet needs. Copyright © 2016 International Association for the Study of Lung Cancer. Published by Elsevier Inc. All rights reserved.

  13. Development status of nuclear power in China and fundamental research progress on PWR primary water chemistry in China

    International Nuclear Information System (INIS)

    Wu, Xinqiang; Liu, Xiahe; Han, En-Hou; Ke, Wei; Xu, Yuming

    2015-01-01

    China's non-fossil fuels are expected to reach 20% in primary energy ratio by 2030. It is urgent for China to speed up the development of nuclear power to increase energy supply, reduce gas emissions and optimize resource allocation. Chinese government slowed down the approval of new nuclear power plant (NPP) projects after Fukushima accident in 2011. At the end of 2012, the State Council approved the nuclear safety program and adjusted long-term nuclear power development plan (2011-2020), the new NPP's projects have been restarted. In June 2015, there are 23 operating units in mainland in China with total installed capacity of about 21.386 GWe; another 26 units are under construction with total installed capacity of 28.5 GWe. The main type of reactors in operation and under construction in China is pressurized water reactor (PWR), including the first AP1000 NPPs in the world (units 1 in Sanmen) and China self-developed Hualong one NPPs (units 5 and 6 in Fuqing). Currently, China's nuclear power development is facing historic opportunities and also a series of challenges. One of the most important is the safety and economy of nuclear power. The optimization of primary water chemistry is one of the most effective ways to minimize radiation field, mitigate material degradation and maintain fuel performance in PWR NPPs, which is also a preferred path to achieve both safety and economy for operating NPPs. In recent years, an increased attention has been paid to fundamental research and engineering application of PWR primary water chemistry in China. The present talk mainly consists of four parts: (1) development status of China's nuclear power industry; (2) safety of nuclear power and operating water chemistry; (3) fundamental research progress on Zn-injected water chemistry in China; (4) summary and future. (author)

  14. COMPARISON OF EFFECTIVENESS OF A PROGRESSIVE MOBILIZATION AND MOZART MUSIC THERAPY ON NON-INVASIVE HEMODYNAMIC STATUS CHANGES IN PATIENTS WITH HEAD INJURY IN THE INTENSIVE CARE UNIT

    Directory of Open Access Journals (Sweden)

    Novi Indriani

    2018-05-01

    Full Text Available Background: The instability of hemodynamic status in patients with head injury with decreased consciousness has an effect on the increase of intracranial pressure. The recovery of hemodynamic status can be done through nursing intervention either by providing a sensory stimulus (music therapy or motor stimulus (progressive mobilization. Objective: To compare the effectiveness of progressive mobilization of level I with Mozart's music therapy on non-invasive hemodynamic status changes in patients with head injury with decreased awareness. Methods: This was a quasy-experimental study with pretest-posttest design. There were 34 samples selected using consecutive sampling, which 17 samples assigned in a group of progressive mobilization and group of music therapy. Paired t-test and Wilcoxon test were used for paired group, and Independent t-test and Mann-Whitney test for unpaired group. Results: Progressive mobilization of level I had significant effect on changes in systolic blood pressure (p = 0.0001, diastolic blood pressure (p = 0.002 and MAP (p = 0.019, and no significant effect on heart rate (p = 0.155, respiration (p = 0.895 and oxygen saturation (p = 0.248. Mozart's music therapy had a significant effect on changes in systolic blood pressure (p = 0.0001, diastolic blood pressure (p = 0.0001, respiration (p= 0.032 and oxygen saturation (p = 0.008, but no effect on MAP (p = 0.561. There was a significant difference between the two interventions in the systolic blood pressure and heart rate variables (p 0.05. Conclusion: The Mozart's music therapy is more effective on non-invasive hemodynamic status changes in patients with head injury with decreased consciousness compared with progressive mobilization of level I.

  15. Effect of supplementation with a lipid-based nutrient supplement on the micronutrient status of children aged 6-18 months living in the rural region of Intibucá, Honduras.

    Science.gov (United States)

    Siega-Riz, Anna M; Estrada Del Campo, Yaniré; Kinlaw, Alan; Reinhart, Gregory A; Allen, Lindsay H; Shahab-Ferdows, Setareh; Heck, Jeff; Suchindran, Chirayath M; Bentley, Margaret E

    2014-05-01

    Lipid-based nutrient supplements (LNS) have been effective in the treatment of acute malnutrition among children. We evaluated the use of LNS supplementation for improving the micronutrient status of young children. A 12-month randomised controlled trial was conducted among children aged 6-18 months living in Intibucá, Honduras. Communities (n = 18) were randomised into clusters matched by poverty indicators (9 intervention, n = 160 and 9 controls, n = 140). Intervention participants received LNS. All children received food vouchers and nutrition education. Primary outcomes included measures of micronutrient status: at baseline, 6 and 12 months' blood were collected for assessment of folate, iron, zinc, riboflavin, and vitamin B12 status; haemoglobin was measured every 3 months; and dietary and anthropometry collected monthly. Longitudinal analyses were based on intent to treat and LNS adherence. Generalised estimating equations were used in the estimation of generalised linear regression models specified for the data. At 6-month follow-up, children in the intervention group had a lower proportion classified as deficient for B12 (43.6%) compared with the control (67.7%; P = 0.03). The intervention group had a higher mean concentration for folate at 6 months (P = 0.06), and improvements continued through 12 months for folate (P = 0.002) and vitamin A deficiency (P = 0.03). This pattern of results, with improved significance, remained in subanalysis based on LNS adherence. These data demonstrate that LNS improved select micronutrient status in young non-malnourished Honduran children. © 2014 John Wiley & Sons Ltd.

  16. Impacts of mothers' occupation status and parenting styles on levels of self-control, addiction to computer games, and educational progress of adolescents.

    Science.gov (United States)

    Abedini, Yasamin; Zamani, Bibi Eshrat; Kheradmand, Ali; Rajabizadeh, Ghodratollah

    2012-01-01

    Addiction to computer (video) games in adolescents and its relationship with educational progress has recently attracted the attention of rearing and education experts as well as organizations and institutes involved in physical and mental health. The current research attempted to propose a structural model of the relationships between parenting styles, mothers' occupation status, and addiction to computer games, self-control, and educational progress of secondary school students. Using multistage cluster random sampling, 500 female and male secondary school students in Kerman (Iran) were selected and studied. The research tools included self-control, parenting styles, and addiction to computer games questionnaires and a self-made questionnaire containing demographic details. The data was analyzed using exploratory factor analysis, Cronbach's alpha coefficient and route analysis (in LISREL). We found self-control to have a linking role in the relationship between four parenting styles and educational progress. Mothers' occupation status was directly and significantly correlated with addiction to computer games. Although four parenting styles directly and significantly affected addiction to computer games, the findings did not support the linking role of addiction to computer games in the relationship between four parenting styles and educational progress. In agreement with previous studies, the current research reflected the impact of four parenting styles on self-control, addiction to computer games, and educational progress of students. Among the parenting styles, authoritative style can affect the severity of addiction to computer games through self-control development. It can thus indirectly influence the educational progress of students. Parents are recommended to use authoritative parenting style to help both self-management and psychological health of their children. The employed mothers are also recommended to have more supervision and control on the degree

  17. Impacts of Mothers’ Occupation Status and Parenting Styles on Levels of Self-Control, Addiction to Computer Games, and Educational Progress of Adolescents

    Science.gov (United States)

    Abedini, Yasamin; Zamani, Bibi Eshrat; Kheradmand, Ali; Rajabizadeh, Ghodratollah

    2012-01-01

    Background Addiction to computer (video) games in adolescents and its relationship with educational progress has recently attracted the attention of rearing and education experts as well as organizations and institutes involved in physical and mental health. The current research attempted to propose a structural model of the relationships between parenting styles, mothers’ occupation status, and addiction to computer games, self-control, and educational progress of secondary school students. Methods Using multistage cluster random sampling, 500 female and male secondary school students in Kerman (Iran) were selected and studied. The research tools included self-control, parenting styles, and addiction to computer games questionnaires and a self-made questionnaire containing demographic details. The data was analyzed using exploratory factor analysis, Cronbach’s alpha coefficient and route analysis (in LISREL). Findings We found self-control to have a linking role in the relationship between four parenting styles and educational progress. Mothers’ occupation status was directly and significantly correlated with addiction to computer games. Although four parenting styles directly and significantly affected addiction to computer games, the findings did not support the linking role of addiction to computer games in the relationship between four parenting styles and educational progress. Conclusion In agreement with previous studies, the current research reflected the impact of four parenting styles on self-control, addiction to computer games, and educational progress of students. Among the parenting styles, authoritative style can affect the severity of addiction to computer games through self-control development. It can thus indirectly influence the educational progress of students. Parents are recommended to use authoritative parenting style to help both self-management and psychological health of their children. The employed mothers are also recommended to

  18. Effect of supplementation with a lipid-based nutrient supplement on the micronutrient status of children aged 6–18 months living in the rural region of Intibucá, Honduras

    Science.gov (United States)

    Background: Lipid-based nutrient supplements (LNS) have been effective in the treatment of acute malnutrition among children. We evaluated the use of LNS supplementation for improving the micronutrient status of young children. Methods: A 12-month randomised controlled trial was conducted among chil...

  19. Weight loss in the first month post-gastroplasty following diet progression with introduction of solid food three weeks after surgery

    OpenAIRE

    ANDRADE, Camila Garcia da Costa; LOBO, Amanda

    2014-01-01

    BACKGROUND: Bariatric surgery is an effective tool in treating severe obesity. It provides significant weight loss in morbidly obese people accompanied by improvement in comorbidities and quality of life. AIM: To investigate the weight loss outcomes in the first month after bariatric surgery after introduction of solids three weeks postoperatively. METHODS: Thirty-two charts of patients who underwent bariatric surgery were analyzed at a private nutritional clinic in São Sebastião do Para...

  20. Visual Acuity Change over 12 Months in the Prospective Progression of Atrophy Secondary to Stargardt Disease (ProgStar) Study: ProgStar Report Number 6.

    Science.gov (United States)

    Kong, Xiangrong; Strauss, Rupert W; Cideciyan, Artur V; Michaelides, Michel; Sahel, José-Alain; Munoz, Beatriz; Ahmed, Mohamed; Ervin, Ann M; West, Sheila K; Cheetham, Janet K; Scholl, Hendrik P N

    2017-11-01

    To estimate the yearly rate of change of best-corrected visual acuity (BCVA) and the risk of loss 1 line or more over 1 year and to identify risk factors for BCVA loss in patients with Stargardt disease (STGD1). Multicenter, prospective cohort study. Two hundred fifty-nine patients (489 eyes) with molecularly confirmed STGD1 enrolled at 9 centers in the United States and Europe. Participants were followed up every 6 months, and data at the baseline and 6- and 12-month visits were analyzed. Best-corrected visual acuity was measured using the Early Treatment Diabetic Retinopathy Study (ETDRS) protocol. Standardized reporting forms were used to collect participants' characteristics and clinical observations. Linear mixed effects models were used to estimate the rate of BCVA loss. Linear models with generalized estimating equations were used to identify risk factors for BCVA loss of 1 line or more over 1 year. Change in BCVA over 1 year. Cross-sectional analysis at baseline showed that earlier symptom onset and longer duration since onset was associated with worse BCVA. Longitudinal analysis showed no overall significant change of BCVA within 12 months, but the rate of BCVA change was significantly different by baseline BCVA (P trials with 1 year's duration. Copyright © 2017 American Academy of Ophthalmology. Published by Elsevier Inc. All rights reserved.

  1. Disease Progression in Mild Dementia due to Alzheimer Disease in an 18-Month Observational Study (GERAS): The Impact on Costs and Caregiver Outcomes.

    Science.gov (United States)

    Jones, Roy W; Lebrec, Jeremie; Kahle-Wrobleski, Kristin; Dell'Agnello, Grazia; Bruno, Giuseppe; Vellas, Bruno; Argimon, Josep M; Dodel, Richard; Haro, Josep Maria; Wimo, Anders; Reed, Catherine

    2017-01-01

    We assessed whether cognitive and functional decline in community-dwelling patients with mild Alzheimer disease (AD) dementia were associated with increased societal costs and caregiver burden and time outcomes. Cognitive decline was defined as a ≥3-point reduction in the Mini-Mental State Examination and functional decline as a decrease in the ability to perform one or more basic items of the Alzheimer's Disease Cooperative Study Activities of Daily Living Inventory (ADCS-ADL) or ≥20% of instrumental ADL items. Total societal costs were estimated from resource use and caregiver hours using 2010 costs. Caregiver burden was assessed using the Zarit Burden Interview (ZBI); caregiver supervision and total hours were collected. Of 566 patients with mild AD enrolled in the GERAS study, 494 were suitable for the current analysis. Mean monthly total societal costs were greater for patients showing functional (+61%) or cognitive decline (+27%) compared with those without decline. In relation to a typical mean monthly cost of approximately EUR 1,400 at baseline, this translated into increases over 18 months to EUR 2,254 and 1,778 for patients with functional and cognitive decline, respectively. The number of patients requiring supervision doubled among patients showing functional or cognitive decline compared with those not showing decline, while caregiver total time increased by 70 and 33%, respectively and ZBI total score by 5.3 and 3.4 points, respectively. Cognitive and, more notably, functional decline were associated with increases in costs and caregiver outcomes in patients with mild AD dementia.

  2. Weight loss in the first month post-gastroplasty following diet progression with introduction of solid food three weeks after surgery.

    Science.gov (United States)

    Andrade, Camila Garcia da Costa; Lobo, Amanda

    2014-01-01

    Bariatric surgery is an effective tool in treating severe obesity. It provides significant weight loss in morbidly obese people accompanied by improvement in comorbidities and quality of life. To investigate the weight loss outcomes in the first month after bariatric surgery after introduction of solids three weeks postoperatively. Thirty-two charts of patients who underwent bariatric surgery were analyzed at a private nutritional clinic in São Sebastião do Paraíso, MG, Brazil; 93,75% of the subjects underwent Roux-en-Y gastric bypass, and 6,25% vertical gastrectomy. The subjects were 16 to 60 years. A body mass index of 30 to 69 Kg/m2 was obtained. Patients were instructed to eat small amounts several times a day, eat slowly, chew foods thoroughly, substitute sugar for sweetener, stop drinking gassy beverages, set the utensils down in between meals, drink only in between meals, avoid processed condiments and fried and greasy foods. In the first month after surgery, the mean weight loss was 9,7% and the percentage of excess weight loss was 23,9%. It was found that there was significant statistical difference in relation to initial and final weight (p=0,00; pfreedom of choice in health care once one does not have to go on food intake modifications for more than three weeks; more nutritional guidelines is followed and prospective weight loss is presented.

  3. Interdependence of plant water status with photosynthetic performance and root defense responses in Vigna radiata (L.) Wilczek under progressive drought stress and recovery.

    Science.gov (United States)

    Sengupta, Debashree; Guha, Anirban; Reddy, Attipalli Ramachandra

    2013-10-05

    The present study investigates the interdependence of plant water status with foliar and root responses in Vigna radiata L.Wilczek under progressive drought. Vegetatively-mature V. radiata plants were subjected to water withdrawal for 3 and 6days (D3 and D6, respectively) and then re-watered subsequently for 6days (6R) for stress-recovery. Changes in plant water status were expressed in terms of leaf and root moisture contents (LMC and RMC, respectively) and leaf relative water content (LRWC). Progressive drought caused apparent decrease in LRWC, LMC and RMC depicting significant level of dehydration of leaf and root tissues. Stomatal limitation alone could not account for the observed decrease in net CO2 assimilation rates (Pn) due to comparatively less decrease in sub-stomatal CO2 (Ci) concentrations with respect to other gas exchange parameters indicating possible involvement of non-stomatal limitations. Analysis of polyphasic chl a fluorescence kinetics during progressive drought showed decreased energy connectivity among PSII units as defined by a positive L-band with highest amplitude during D6. Efficiency of electron flux from OEC towards PSII acceptor side was not significantly affected during drought conditions as evidenced by the absence of a positive K-band. Increasing root-level water-limitation enforced a gradual oxidative stress through H2O2 accumulation and membrane lipid peroxidation in V. radiata roots exhibiting drastic enhancement of proline content and a significant but gradual increase in ascorbic acid content as well as guaiacol peroxidase activity under progressive drought. Expression analysis of Δ(1) pyrroline-5-carboxylate synthetase (P5CS) through real time PCR and enzyme activity studies showed a strong positive correlation between VrP5CS gene expression, enzyme activity and proline accumulation in the roots of V. radiata under progressive drought and recovery. Drought-induced changes in root moisture content (RMC) showed positive linear

  4. Walking speed, rather than Expanded Disability Status Scale, relates to long-term patient-reported impact in progressive MS

    NARCIS (Netherlands)

    Bosma, L.V.A.E.; Kragt, J.J.; Polman, C.H.; Uitdehaag, B.M.J.

    2013-01-01

    Objective: To study the relationships between 1-2 year changes in well-known physician-rated measurements (Expanded Disability Status Scale (EDSS), Timed 25-Foot Walk (T25FW), 9-Hole Peg Test (9HPT)) and the long-term (= 5 years) outcome in patient-reported outcome (PRO) measures (Multiple Sclerosis

  5. Differential relationship between physical activity and progression to diabetes by glucose tolerance status: the Inter99 Study

    DEFF Research Database (Denmark)

    Engberg, S; Glümer, C; Witte, D R

    2010-01-01

    The aim of the study was to analyse how strongly commuting and leisure-time physical activity affect progression to diabetes and to study whether this relationship is different in individuals with isolated impaired fasting glucose (i-IFG) and isolated impaired glucose tolerance (i-IGT)....

  6. Status report on speech research. A report on the status and progress of studies on the nature of speech, instrumentation for its investigation, and practical applications

    Science.gov (United States)

    Liberman, A. M.

    1985-10-01

    This interim status report on speech research discusses the following topics: On Vagueness and Fictions as Cornerstones of a Theory of Perceiving and Acting: A Comment on Walter (1983); The Informational Support for Upright Stance; Determining the Extent of Coarticulation-effects of Experimental Design; The Roles of Phoneme Frequency, Similarity, and Availability in the Experimental Elicitation of Speech Errors; On Learning to Speak; The Motor Theory of Speech Perception Revised; Linguistic and Acoustic Correlates of the Perceptual Structure Found in an Individual Differences Scaling Study of Vowels; Perceptual Coherence of Speech: Stability of Silence-cued Stop Consonants; Development of the Speech Perceptuomotor System; Dependence of Reading on Orthography-Investigations in Serbo-Croatian; The Relationship between Knowledge of Derivational Morphology and Spelling Ability in Fourth, Sixth, and Eighth Graders; Relations among Regular and Irregular, Morphologically-Related Words in the Lexicon as Revealed by Repetition Priming; Grammatical Priming of Inflected Nouns by the Gender of Possessive Adjectives; Grammatical Priming of Inflected Nouns by Inflected Adjectives; Deaf Signers and Serial Recall in the Visual Modality-Memory for Signs, Fingerspelling, and Print; Did Orthographies Evolve?; The Development of Children's Sensitivity to Factors Inf luencing Vowel Reading.

  7. The Additional Costs per Month of Progression-Free Survival and Overall Survival: An Economic Model Comparing Everolimus with Cabozantinib, Nivolumab, and Axitinib for Second-Line Treatment of Metastatic Renal Cell Carcinoma.

    Science.gov (United States)

    Swallow, Elyse; Messali, Andrew; Ghate, Sameer; McDonald, Evangeline; Duchesneau, Emilie; Perez, Jose Ricardo

    2018-04-01

    When considering optimal second-line treatments for metastatic renal cell carcinoma (mRCC), clinicians and payers seek to understand the relative clinical benefits and costs of treatment. To use an economic model to compare the additional cost per month of overall survival (OS) and of progression-free survival (PFS) for cabozantinib, nivolumab, and axitinib with everolimus for the second-line treatment of mRCC from a third-party U.S. payer perspective. The model evaluated mean OS and PFS and costs associated with drug acquisition/administration; adverse event (AE) treatment; monitoring; and postprogression (third-line treatment, monitoring, and end-of-life costs) over 1- and 2-year horizons. Efficacy, safety, and treatment duration inputs were estimated from regimens' pivotal clinical trials; for everolimus, results were weighted across trials. Mean 1- and 2-year OS and mean 1-year PFS were estimated using regimens' reported OS and PFS Kaplan-Meier curves. Dosing and administration inputs were consistent with approved prescribing information and the clinical trials used to estimate efficacy and safety inputs. Cost inputs came from published literature and public data. Additional cost per additional month of OS or PFS was calculated using the ratio of the cost difference per treated patient and the corresponding difference in mean OS or PFS between everolimus and each comparator. One-way sensitivity analyses were conducted by varying efficacy and cost inputs. Compared with everolimus, cabozantinib, nivolumab, and axitinib were associated with 1.6, 0.3, and 0.5 additional months of PFS, respectively, over 1 year. Cabozantinib and nivolumab were associated with additional months of OS compared with everolimus (1 year: 0.7 and 0.8 months; 2 years: 1.6 and 2.3 months; respectively); axitinib was associated with fewer months (1 year: -0.2 months; 2 years: -0.7 months). The additional costs of treatment with cabozantinib, nivolumab, or axitinib versus everolimus over 1

  8. Gestational Vitamin 25(OH)D Status as a Risk Factor for Receptive Language Development: A 24-Month, Longitudinal, Observational Study.

    Science.gov (United States)

    Tylavsky, Frances A; Kocak, Mehmet; Murphy, Laura E; Graff, J Carolyn; Palmer, Frederick B; Völgyi, Eszter; Diaz-Thomas, Alicia M; Ferry, Robert J

    2015-12-02

    Emerging data suggest that vitamin D status during childhood and adolescence can affect neurocognitive development. The purpose of this study was to investigate whether gestational 25(OH)D status is associated with early childhood cognitive and receptive language development. The Conditions Affecting Neurocognitive Development and Learning in Early Childhood Study (CANDLE) study enrolled 1503 mother-child dyads during the second trimester of healthy singleton pregnancies from Shelby County TN. Among 1020 participants of the total CANDLE cohort for whom 25(OH)D levels were available, mean gestational 25(OH)D level during the second trimester was 22.3 ng/mL (range 5.9-68.4), with 41.7% of values receptive language development (p < 0.017), but not cognitive or expressive language.

  9. Periodontal health status in patients treated with the Invisalign(®) system and fixed orthodontic appliances: A 3 months clinical and microbiological evaluation.

    Science.gov (United States)

    Levrini, Luca; Mangano, Alessandro; Montanari, Paola; Margherini, Silvia; Caprioglio, Alberto; Abbate, Gian Marco

    2015-01-01

    The aim of this prospective study was to compare the periodontal health and the microbiological changes via real-time polymerase chain reaction (PCR) in patients treated with fixed orthodontic appliances and Invisalign(®) system (Align Technology, Santa Clara, California). Seventy-seven patients were enrolled in this study and divided into three groups (Invisalign(®) group, fixed orthodontic appliances group and control group). Plaque index, probing depth, bleeding on probing were assessed. Total biofilm mass and periodontal pathogens were analyzed and detected via real-time PCR. All these data were analyzed at the T0 (beginning of the treatment) T1 (1-month) and T2 (3 months); and statistically compared using the Mann-Whitney test for independent groups. After 1-month and after 3 months of treatment there was only one sample with periodontopathic anaerobes found in patient treated using fixed orthodontic appliances. The Invisalign(®) group showed better results in terms of periodontal health and total biofilm mass compared to the fixed orthodontic appliance group. A statistical significant difference (P < 0.05) at the T2 in the total biofilm mass was found between the two groups. Patients undergoing orthodontic treatment with the Invisalign(®) System show a superior periodontal health in the short-term when compared to patients in treatment with fixed orthodontic appliances. Invisalign(®) should be considered as a first treatment option in patients with risk of developing periodontal disease.

  10. Patient satisfaction with psychotropic drugs: sensitivity to change and relationship to clinical status, quality-of-life, compliance and effectiveness of treatment. Results from a nation-wide 6-month prospective study.

    Science.gov (United States)

    Gasquet, Isabelle; Tcherny-Lessenot, Stéphanie; Lépine, Jean-Pierre; Falissard, Bruno

    2006-12-01

    To see if patient satisfaction with psychotropics (PSP) could be used as a patient-oriented outcome variable in the evaluation of PSP drugs in clinical epidemiological studies, relationships between PSP, clinical status, QoL, compliance and the type of antipsychotic were analyzed. Elements of validation of PSP were also assessed. In a 6-month prospective study, 933 schizophrenic outpatients with initiation or change to their antipsychotic treatment were enrolled. Psychiatrists completed five CGI-SCH scales (positive, negative, cognitive, depressive and global), hospitalization, compliance, and prescription variables. Patients completed PSP, EuroQoL scales, sexual function and compliance variables. A satisfactory structural equation model was obtained showing significant relationships PSP/compliance (coef.=0.16), QoL/PSP (coef.=0.37), clinical status/QoL (coef.=0.61), clinical status/compliance (coef.=0.09). Patients receiving olanzapine were more satisfied than patients receiving other atypicals (coef.=012) and had better clinical status than patients treated with typicals (coef.=0.08). Evolution of PSP was related to clinical status, QoL, and continuation of treatment (all Pmeasure was not sufficiently sensitive to change. Multi-item questionnaires evaluating different dimensions are needed.

  11. On Medical Progress and Health Care Demand: A Ces Perspective Using the Grossman Model of Health Status.

    Science.gov (United States)

    Batinti, Alberto

    2015-12-01

    I propose an application of the pure-consumption version of the Grossman model of health care demand, where utility depends on consumption and health status and health status on medical care and health technology. I derive the conditions under which an improvement in health care technology leads to an increase/decrease in health care consumption. In particular, I show how the direction of the effect depends on the relationship between the constant elasticity of substitution parameters of the utility and health production functions. I find that, under the constancy assumption, the ratio of the two elasticity of substitution parameters determines the direction of a technological change on health care demand. On the other hand, the technology share parameter in the health production function contributes to the size but not to the direction of the technological effect. I finally explore how the ratio of the elasticity of substitution parameters work in measurement and practice and discuss how future research may use the theoretical insight provided here. Copyright © 2014 John Wiley & Sons, Ltd.

  12. Case Report: Gollop-Wolfgang Complex in a 5 month old baby [v3; ref status: indexed, http://f1000r.es/53y

    Directory of Open Access Journals (Sweden)

    Ihtesham A. Qureshi

    2015-02-01

    Full Text Available Skeletal dysplasias are disorders associated with a generalized abnormality in the skeleton. The Gollop-Wolfgang complex (GWC is a limb deficiency disorder and an unusual limb malformation with highly variable manifestations. Here we report an interesting case of a 5-month old male baby from India with Gollop-Wolfgang Complex showing bifurcation of the right femur, ectrodactyly of both feet, ectrodactyly of left hand, syndactyly of right hand and unusual presentation of bilateral fibular agenesis and caudal (Sacrococcygeal agenesis. The etiology of GWC in this 5 month old male baby could possibly be attributed to spontaneous gene mutation. The clinical, radiographic findings and the unusual presentation are presented in detail.

  13. Dietary fiber intake is associated with chronic kidney disease (CKD) progression and cardiovascular risk, but not protein nutritional status, in adults with CKD.

    Science.gov (United States)

    Lu, Lu; Huang, Yan-Feng; Wang, Ming-Qing; Chen, De-Xiu; Wan, Heng; Wei, Lian-Bo; Xiao, Wei

    Evidence suggests that dietary fiber benefits patients with chronic kidney disease (CKD); however, this conclusion requires further validation. In this study, we examined the effects of dietary fiber on kidney function, inflammation, indoxyl sulfate, nutritional status, and cardiovascular risk in patients with advanced CKD. We performed linear regressions to assess the association between dietary fiber intake and CKD parameters. The aforementioned parameters were compared over an 18-month follow- up period. Kaplan-Meier analysis was used to investigate the association between fiber intake and Cardiac vascular disease (CVD). In total, 157 patients were included in this study. Dietary fiber and inflammatory indices were associated (interleukin [IL]-6: β=-0.024, p=0.035). The differential estimated glomerular filtration rate (ΔeGFR) as well as levels of C-reactive protein, IL-6, indoxyl sulfate, and serum cholesterol in the higher fiber intake (>=25 g/day) group were lower than those in the lower fiber intake (patients in the higher protein intake group (pintake may be a protective factor associated with CVD (hazard ratio=0.537 and 0.305- 0.947). The protein nutritional status was not different between the two groups (p>0.05). Our results suggest that increasing fiber intake can retard the decrease in the eGFR; can reduce the levels of proinflammatory factors, indoxyl sulfate, and serum cholesterol; and is negatively associated with cardiovascular risk, but does not disrupt the nutritional status of patients with CKD.

  14. Immunohistochemical analysis of aldehyde dehydrogenase isoforms and their association with estrogen-receptor status and disease progression in breast cancer

    Directory of Open Access Journals (Sweden)

    Opdenaker LM

    2014-12-01

    Full Text Available Lynn M Opdenaker,1,2 Kimberly M Arnold,1,3 Ryan T Pohlig,3,4 Jayasree S Padmanabhan,1 Daniel C Flynn,1,3 Jennifer Sims-Mourtada1–3 1Center for Translational Cancer Research, Helen F Graham Cancer Center, Christiana Care Health Services, Inc., Newark, Delaware, USA; 2Department of Biological Sciences, 3Department of Medical Laboratory Sciences, 4Biostatistics Core Facility, University of Delaware, Newark, Delaware, USA Abstract: In many types of tumors, especially breast tumors, aldehyde dehydrogenase (ALDH activity has been used to identify cancer stem-like cells within the tumor. The presence and quantity of these cells are believed to predict the response of tumors to chemotherapy. Therefore, identification and eradication of these cells would be necessary to cure the patient. However, there are 19 different ALDH isoforms that could contribute to the enzyme activity. ALDH1A1 and ALDH1A3 are among the isoforms mostly responsible for the increased ALDH activity observed in these stem-like cells, although the main isoforms vary in different tissues and tumor types. In the study reported here, we attempted to determine if ALDH1A1 or ALDH1A3, specifically, correlate with tumor stage, grade, and hormone-receptor status in breast-cancer patients. While there was no significant correlation between ALDH1A1 and any of the parameters tested, we were able to identify a positive correlation between ALDH1A3 and tumor stage in triple-negative cancers. In addition, ALDH1A3 was negatively correlated with estrogen-receptor status. Our data suggest that ALDH1A3 could be utilized as a marker to identify stem-like cells within triple-negative tumors. Keywords: breast tumor, ALDH, ALDH1A1, ALDH1A3, stem-like cells, triple-negative cancer

  15. [The ban on smoking in public places (Decree No. 2006-1386 of 15th November 2006): Impact over 12 months on smoking status of hospital nurses].

    Science.gov (United States)

    Maurel-Donnarel, E; Baumstarck-Barrau, K; Barlesi, F; Lehucher-Michel, M-P

    2010-03-01

    In France, the decree No. 2006-1386 banned smoking in public places such as hospitals. The aim of our study was to describe the impact of the legislation on the smoking status of hospital nurses. A descriptive study was undertaken in a university hospital of Marseilles, under the responsibility of the occupational medicine service. Between April and June 2008, a questionnaire was distributed to the nurses who had been working for more than one year. The following data were collected: demographic information, smoking status, behaviour and attitudes regarding smoking addiction, knowledge regarding existing preventive measures. Sixty-four percent of 715 eligible subjects responded; thirty percents reported themselves as current smokers, 25 % as ex-smokers and 45 % as non-smokers. Among the smokers, 68 % said that they had decreased their tobacco consumption during their working hours and 28 % their overall daily consumption. Among ex-smokers, 20 % declared that they were in the process of quitting. The nurses had decreased their tobacco consumption at work and these positive results should be confirmed over a long-term perspective. The preventive role of the occupational physician could be reinforced. Copyright 2010 SPLF. Published by Elsevier Masson SAS. All rights reserved.

  16. Effect of Omega-3 and Vitamins E + C Supplements on the Concentration of Serum B-Vitamins and Plasma Redox Aminothiol Antioxidant Status in Elderly Men after Strength Training for Three Months.

    Science.gov (United States)

    Stea, Tonje Holte; Stølevik, Solvor B; Berntsen, Sveinung; Ezzathkah Bastani, Nasser; Paulsen, Gøran; Lohne Seiler, Hilde; Hetlelid, Ken J; Blomhoff, Rune; Mansoor, Mohammad Azam

    2016-01-01

    Data on redox plasma aminothiol status in individuals on strength training are very limited. Therefore, we studied the effect of omega-3 and vitamins E + C supplementation on the concentration of B-vitamins and redox aminothiol status in elderly men after strength training for 3 months. Healthy men, age 60 ± 6 (mean ± SD) were randomly divided into 3 groups: group I received placebo (n = 17), group II consumed omega-3 (700 mg, n = 17), and group III consumed vitamins E + C (235 mg +1 g, n = 16) daily for 3 months. All participants completed a strength training program for the same period. The concentration of serum vitamin B12 decreased and the concentration of serum folate increased in group I after the intervention (p = 0.01, p = 0.009). The concentration of plasma 5-pyridoxal phosphate decreased in groups II and III (p = 0.03 and p = 0.01), whereas the concentration of serum uric acid decreased only in group II (p = 0.02). We detected an increase in the concentration of reduced form of aminothiols in all groups (p vitamins E + C supplementation affect the concentrations of serum B-vitamins and redox plasma aminothiol status in healthy elderly men on strength training. © 2016 S. Karger AG, Basel.

  17. EASYTRACK 30 month Progress Report from DTU

    DEFF Research Database (Denmark)

    Larsen, Erik; De Chiffre, Leonardo; Savio, Enrico

    This report is made as a part of the project Easytrac, an EU project under the programme: Competitive and Sustainable Growth: Contract No: G6RD-CT-2000-00188 coordinated by UNIMETRIK S.A. (Spain). The project is concerned with low uncertainty calibrations on coordinate measuring machines. The Cen....... The Centre for Geometrical Metrology (CGM) at the Technical University of Denmark collaborates with DIMEG, University of Padova, Italy....

  18. Standardized Treatment of Neonatal Status Epilepticus Improves Outcome.

    Science.gov (United States)

    Harris, Mandy L; Malloy, Katherine M; Lawson, Sheena N; Rose, Rebecca S; Buss, William F; Mietzsch, Ulrike

    2016-12-01

    We aimed to decrease practice variation in treatment of neonatal status epilepticus by implementing a standardized protocol. Our primary goal was to achieve 80% adherence to the algorithm within 12 months. Secondary outcome measures included serum phenobarbital concentrations, number of patients progressing from seizures to status epilepticus, and length of hospital stay. Data collection occurred for 6 months prior and 12 months following protocol implementation. Adherence of 80% within 12 months was partially achieved in patients diagnosed in our hospital; in pretreated patients, adherence was not achieved. Maximum phenobarbital concentrations were decreased (56.8 vs 41.0 µg/mL), fewer patients progressed from seizures to status epilepticus (46% vs 36%), and hospital length of stay decreased by 9.7 days in survivors. In conclusion, standardized, protocol-driven treatment of neonatal status epilepticus improves consistency and short-term outcome. © The Author(s) 2016.

  19. The impact of a food assistance program on nutritional status, disease progression, and food security among people living with HIV in Uganda.

    Science.gov (United States)

    Rawat, Rahul; Faust, Elizabeth; Maluccio, John A; Kadiyala, Suneetha

    2014-05-01

    Although the last decade has seen increased access to antiretroviral therapy across the developing world, widespread food insecurity and undernutrition continue to compromise an effective response to the AIDS epidemic. Limited evidence exists on the potential benefit of food security and nutrition interventions to people living with HIV (PLHIV). We capitalized on an existing intervention to PLHIV in Uganda and conducted a prospective quasi-experimental study evaluating the impact of a monthly household food basket, provided to food insecure antiretroviral therapy-naive PLHIVs for 12 months. The outcomes of interest measured at baseline and follow-up were nutritional status [body mass index; mid-upper arm circumference and hemoglobin (Hb) concentrations], disease severity (CD4 count), and 2 measures of food security: diet quality (Individual Dietary Diversity Score) and food access (Household Food Insecurity Access Scale). We used difference-in-difference propensity score matching to examine the impact of food assistance. Over 12 months, food assistance significantly increased body mass index by 0.6 kg/m (P Insecurity Access Scale, by 2.1 points (P insecurity.

  20. HTGR accident initiation and progression analysis status report. Volume VII. Occupational radiation exposures from gas-borne and plateout activities

    International Nuclear Information System (INIS)

    1976-01-01

    As a part of the Accident Initiation and Progression Analysis (AIPA) program, calculations were performed of the occupational dose rates and man-rem exposures from gas-borne and plateout activities in a reference 3000-MW(t) HTGR plant. The study included a preliminary survey to determine the most important contributors by operation or radiation source to the man-rem exposures. This survey was followed by detailed calculations for the most important cases. Median and 95 percent-confidence-level man-rem exposures per year were obtained for the gaseous activity in the containment building, moisture monitor system, analytic instrumentation, helium regeneration system, gas waste system, and reflector-block shipping. Median and 95 percent-confidence-level man-rem exposures per operation were obtained for the main-circulator removal, steam-generator tube plugging, and steam-generator removal and replacement. For each of these cases, the contributions to the man-rem exposures were calculated for the important isotopes

  1. Present status of technology development on decommissioning and waste management in Nuclear Cycle Backend Directorate. Progress in 2009

    International Nuclear Information System (INIS)

    Takahashi, Kuniaki; Ishigami, Tsutomu; Funabashi, Hideyuki; Meguro, Yoshihiro; Tachibana, Mitsuo

    2010-11-01

    It is an important issue to take measures against the matters on decommissioning of retired nuclear facilities and management of low-level radioactive waste arising from research activities and operation of nuclear facilities, and the measures must be taken with rational way by ensuring the safety. As the development, improvement, and proper deployment of technologies will be key factors, a technology development program is under way in Nuclear Cycle Backend Directorate taking account of these matters in cooperation with research and development institutes/centers in Japan Atomic Energy Agency. The technology development items are selected from the viewpoints of systematic implementation of measures and cost reduction; these include the development of computer systems for planning and evaluation of decommissioning programs, supercritical CO 2 fluid leaching method for decontamination, nitrate-ion degradation method, simple and rapid determination method for radioactivity of radioactive waste, safety assessment for waste disposal and so on. This report describes outline and progress of the technology development program conducted in FY2009 by the research and development unit. (author)

  2. From Centralized Disassembly to Life Cycle Management: Status and Progress of E-waste Treatment System in China

    Science.gov (United States)

    Song, Xiaolong; Yang, Jianxin; Lu, Bin; Yang, Dong

    2017-01-01

    China is now facing e-waste problems from both growing domestic generation and illegal imports. Many stakeholders are involved in the e-waste treatment system due to the complexity of e-waste life cycle. Beginning with the state of the e-waste treatment industry in China, this paper summarizes the latest progress in e-waste management from such aspects as the new edition of the China RoHS Directive, new Treatment List, new funding subsidy standard, and eco-design pilots. Thus, a conceptual model for life cycle management of e-waste is generalized. The operating procedure is to first identify the life cycle stages of the e-waste and extract the important life cycle information. Then, life cycle tools can be used to conduct a systematic analysis to help decide how to maximize the benefits from a series of life cycle engineering processes. Meanwhile, life cycle thinking is applied to improve the legislation relating to e-waste so as to continuously improve the sustainability of the e-waste treatment system. By providing an integrative framework, the life cycle management of e-waste should help to realize sustainable management of e-waste in developing countries.

  3. Daddy Months

    OpenAIRE

    Volker Meier; Helmut Rainer

    2014-01-01

    We consider a bargaining model in which husband and wife decide on the allocation of time and disposable income. Since her bargaining power would go down otherwise more strongly, the wife agrees to having a child only if the husband also leaves the labor market for a while. The daddy months subsidy enables the couple to overcome a hold-up problem and thereby improves efficiency. However, the same ruling harms cooperative couples and may also reduce welfare in an endogenous taxation framework.

  4. Diffusion tensor MRI shows progressive changes in the hippocampus and dentate gyrus after status epilepticus in rat - histological validation with Fourier-based analysis.

    Science.gov (United States)

    Salo, Raimo A; Miettinen, Tuukka; Laitinen, Teemu; Gröhn, Olli; Sierra, Alejandra

    2017-05-15

    Imaging markers for monitoring disease progression, recovery, and treatment efficacy are a major unmet need for many neurological diseases, including epilepsy. Recent evidence suggests that diffusion tensor imaging (DTI) provides high microstructural contrast even outside major white matter tracts. We hypothesized that in vivo DTI could detect progressive microstructural changes in the dentate gyrus and the hippocampal CA3bc in the rat brain after status epilepticus (SE). To test this hypothesis, we induced SE with systemic kainic acid or pilocarpine in adult male Wistar rats and subsequently scanned them using in vivo DTI at five time-points: prior to SE, and 10, 20, 34, and 79 days post SE. In order to tie the DTI findings to changes in the tissue microstructure, myelin- and glial fibrillary acidic protein (GFAP)-stained sections from the same animals underwent Fourier analysis. We compared the Fourier analysis parameters, anisotropy index and angle of myelinated axons or astrocyte processes, to corresponding DTI parameters, fractional anisotropy (FA) and the orientation angle of the principal eigenvector. We found progressive detectable changes in DTI parameters in both the dentate gyrus (FA, axial diffusivity [D || ], linear anisotropy [CL] and spherical anisotropy [CS], pFourier analysis revealed that both myelinated axons and astrocyte processes played a role in the water diffusion anisotropy changes detected by DTI in individual portions of the dentate gyrus (suprapyramidal blade, mid-portion, and infrapyramidal blade). In the whole dentate gyrus, myelinated axons markedly contributed to the water diffusion changes. In CA3bc as well as in CA3b and CA3c, both myelinated axons and astrocyte processes contributed to water diffusion anisotropy and orientation. Our study revealed that DTI is a promising method for noninvasive detection of microstructural alterations in the hippocampus proper. These alterations may be potential imaging markers for epileptogenesis

  5. NAFLD as a Sexual Dimorphic Disease: Role of Gender and Reproductive Status in the Development and Progression of Nonalcoholic Fatty Liver Disease and Inherent Cardiovascular Risk.

    Science.gov (United States)

    Ballestri, Stefano; Nascimbeni, Fabio; Baldelli, Enrica; Marrazzo, Alessandra; Romagnoli, Dante; Lonardo, Amedeo

    2017-06-01

    Nonalcoholic fatty liver disease (NAFLD) spans steatosis through nonalcoholic steatohepatis, cirrhosis, and hepatocellular carcinoma (HCC) associated with striking systemic features and excess cardiovascular and liver-related mortality. The pathogenesis of NAFLD is complex and multifactorial. Endocrine derangements are closely linked with dysmetabolic traits. For example, in animal and human studies, female sex is protected from dysmetabolism thanks to young individuals' ability to partition fatty acids towards ketone body production rather than very low density lipoprotein (VLDL)-triacylglycerol, and to sex-specific browning of white adipose tissue. Ovarian senescence facilitates both the development of massive hepatic steatosis and the fibrotic progression of liver disease in an experimental overfed zebrafish model. Consistently, estrogen deficiency, by potentiating hepatic inflammatory changes, hastens the progression of disease in a dietary model of nonalcoholic steatohepatitis (NASH) developing in ovariectomized mice fed a high-fat diet. In humans, NAFLD more often affects men; and premenopausal women are equally protected from developing NAFLD as they are from cardiovascular disease. It would be expected that early menarche, definitely associated with estrogen activation, would produce protection against the risk of NAFLD. Nevertheless, it has been suggested that early menarche may confer an increased risk of NAFLD in adulthood, excess adiposity being the primary culprit of this association. Fertile age may be associated with more severe hepatocyte injury and inflammation, but also with a decreased risk of liver fibrosis compared to men and postmenopausal status. Later in life, ovarian senescence is strongly associated with severe steatosis and fibrosing NASH, which may occur in postmenopausal women. Estrogen deficiency is deemed to be responsible for these findings via the development of postmenopausal metabolic syndrome. Estrogen supplementation may at

  6. Study of wheat breakfast rolls fortified with folic acid. The effect on folate status in women during a 3-month intervention.

    Science.gov (United States)

    Johansson, Madelene; Witthöft, Cornelia M; Bruce, Ake; Jägerstad, Margaretha

    2002-12-01

    Folate has come into focus due to its protective role against child birth defects such as neural tube defects (NTD). Swedish authorities recommend all fertile women to increase their folate intake to 400 microg/day by eating folate-rich foods. Because not all women follow these recommendations, there is a discussion today about whether Sweden should introduce folic acid fortification in wheat flour and sifted rye flour. This decision needs knowledge about the bioavailability of folic acid from fortified foods. To investigate effects of two folic acid fortification levels on folate status in healthy female volunteers and to study the folic acid stability during the baking procedure and storage of the fortified breakfast rolls. Twenty-nine healthy women were recruited. Folic acid-fortified wheat breakfast rolls were baked with the purpose to contain 200 microg folic acid/roll (roll L) and 400 microg folic acid/roll (roll H). Fourteen women were given one roll/day of roll L (group L) and 15 one roll/day of roll H (group H) during 12 weeks of intervention. Fasting venous blood samples were collected on days 0, 30, 60 and 90. Serum homocysteine concentrations were determined using an immunoassay. Serum and erythrocyte folate concentrations were analysed using a protein-binding assay with fluorescent quantification. The folic acid concentration in the breakfast rolls was analysed by HPLC on days 0, 30, 60 and 90. Total folate concentration was measured with microbiological assay on day 45. Group L Group L had initially an average erythrocyte folate concentration of 577 +/- 93 nmol/L. After 90 days of intervention, an increase of 20 % (p level of 18.7 +/- 4.8 nmol/L at day 0. Thereafter, all women of group H had serum concentrations at or above the upper limit of quantification (23 nmol/L). At day 0, mean serum homocysteine concentrations were 8.4 +/- 1.7 micromol/L, which decreased by 16 % (p level of fortification seems to be sufficient to improve the folate status

  7. The Relationship between Number of Fruits, Vegetables, and Noncore Foods Tried at Age 14 Months and Food Preferences, Dietary Intake Patterns, Fussy Eating Behavior, and Weight Status at Age 3.7 Years.

    Science.gov (United States)

    Mallan, Kimberley M; Fildes, Alison; Magarey, Anthea M; Daniels, Lynne A

    2016-04-01

    We examined whether exposure to a greater number of fruits, vegetables, and noncore foods (ie, nutrient poor and high in saturated fats, added sugars, or added salt) at age 14 months was related to children's preference for and intake of these foods as well as maternal-reported food fussiness and measured child weight status at age 3.7 years. This study reports secondary analyses of longitudinal data from mothers and children (n=340) participating in the NOURISH randomized controlled trial. Exposure was quantified as the number of food items (n=55) tried by a child from specified lists at age 14 months. At age 3.7 years, food preferences, intake patterns, and fussiness (also at age 14 months) were assessed using maternal-completed, established questionnaires. Child weight and length/height were measured by study staff at both age points. Multivariable linear regression models were tested to predict food preferences, intake patterns, fussy eating, and body mass index z score at age 3.7 years adjusting for a range of maternal and child covariates. Having tried a greater number of vegetables, fruits, and noncore foods at age 14 months predicted corresponding preferences and higher intakes at age 3.7 years but did not predict child body mass index z score. Adjusting for fussiness at age 14 months, having tried more vegetables at age 14 months was associated with lower fussiness at age 3.7 years. These prospective analyses support the hypothesis that early taste and texture experiences influence subsequent food preferences and acceptance. These findings indicate introduction to a variety of fruits and vegetables and limited noncore food exposure from an early age are important strategies to improve later diet quality. Copyright © 2016 Academy of Nutrition and Dietetics. Published by Elsevier Inc. All rights reserved.

  8. Status of Development of Premature Children from 4 to 12 Months in the Neonatal Intensive Care Unit (NICU Admission Based on the ASQ Questionnaire

    Directory of Open Access Journals (Sweden)

    sara Kazeroono

    2014-12-01

    Full Text Available Backgrounds & aim: Early diagnosis of developmental delays in children with high risk history of hospitalization in the intensive care unit is essential. Children with one or more risk factors before or around birth are more at risk for developmental delay. The aim of this study was to determine the evolution and history of premature children admitted to the neonatal intensive care unit. Methods: the present descriptive study was conducted on 80 premature children admitted to the neonatal intensive care unit of the Imam Sajad (AS hospital, Yasuj, Iran, with a history of developmental delay at the ages of 4, 6.12 months using the ASQ questionnaire. The questionnaire contains 30 questions including five fields such as communication, gross motor, fine motor, social-personal, problem solving. Along with questionnaire, other essential information were completed. The collected data were analyzed using Chi-square test. Results: among 80 patients, 43 cases (53.8 % were male, with an average weight of 1734.37+-445.50 gr. Regarding communication, gross motor, fine motor, social-personal, problem solving, the results were abnormal at the rate of 10, 30, 27.5, 23.8 and 23.8% respectively. There was no significant relationship found among different fields of development, birth weight, gestational age and Apgar score a significant relationship was found. A significant relationship between infants born through normal delivery and infants born via Caesarean section was realized (p<0.05. Conclusion: Despite the natural evolution, the majority of premature children with a history of NICU admission, a significant number have developmental disorder and need to consider early to avoid complications in the future.

  9. Factors that influence fatigue status in patients with severe rheumatoid arthritis (RA) and good disease outcome following 6 months of TNF inhibitor therapy: a comparative analysis.

    LENUS (Irish Health Repository)

    Minnock, Patricia

    2015-11-01

    The objective of the present study is to determine the factors associated with persistent fatigue in patients with severe rheumatoid arthritis (RA) and good disease response to 6 months of tumour necrosis factor inhibitor therapy. Eligible patients with either persistent (PF) or no fatigue (NF) were compared. Using validated questionnaires and bivariate analysis, this cross-sectional survey explored if clinical characteristics, pain, self-efficacy, sleep and mood\\/depression differed between groups. Patients with PF (PF; NF) (n = 28; 28) reported significantly more overall pain (11.3 ± 9.4 (0-33); 6.9 ± 8.9 (0-33)), more recent and current pain intensity (41.4 ± 26.6 (0-80) 24.4 ± 26.6 (0-100) and depression (11.8 ± 7.5 (1-35); 8.2 ± 6.6 (0-26)), than the NF group. There was no significant difference between groups in self-efficacy and both groups experienced poor sleep quality (Pittsburgh Sleep Quality Index >5). Despite having good disease response, the PF group had significantly higher rheumatoid factor incidence, disease activity score-28, early morning stiffness duration and lower incidence of ever-failing disease-modifying anti-rheumatic drugs than the NF group. These findings enhance the fatigue literature in patients with RA prescribed tumour necrosis factor (TNF) inhibition therapy, identifying the potentially modifiable factors of pain and depression, previously demonstrated to be strongly associated with fatigue in non-biologic populations. In addition, this study highlights the association between persistent fatigue and an on-going state of low disease activity. This infers that more judicious disease management could minimise the symptom burden of pain and depression and consequentially fatigue.

  10. Clinical efficacy and safety of a light mask for prevention of dark adaptation in treating and preventing progression of early diabetic macular oedema at 24 months (CLEOPATRA): a multicentre, phase 3, randomised controlled trial.

    Science.gov (United States)

    Sivaprasad, Sobha; Vasconcelos, Joana C; Prevost, A Toby; Holmes, Helen; Hykin, Philip; George, Sheena; Murphy, Caroline; Kelly, Joanna; Arden, Geoffrey B

    2018-05-01

    We aimed to assess 24-month outcomes of wearing an organic light-emitting sleep mask as an intervention to treat and prevent progression of non-central diabetic macular oedema. CLEOPATRA was a phase 3, single-blind, parallel-group, randomised controlled trial undertaken at 15 ophthalmic centres in the UK. Adults with non-centre-involving diabetic macular oedema were randomly assigned (1:1) to wearing either a light mask during sleep (Noctura 400 Sleep Mask, PolyPhotonix Medical, Sedgefield, UK) or a sham (non-light) mask, for 24 months. Randomisation was by minimisation generated by a central web-based computer system. Outcome assessors were masked technicians and optometrists. The primary outcome was the change in maximum retinal thickness on optical coherence tomography (OCT) at 24 months, analysed using a linear mixed-effects model incorporating 4-monthly measurements and baseline adjustment. Analysis was done using the intention-to-treat principle in all randomised patients with OCT data. Safety was assessed in all patients. This trial is registered with Controlled-Trials.com, number ISRCTN85596558. Between April 10, 2014, and June 15, 2015, 308 patients were randomly assigned to wearing the light mask (n=155) or a sham mask (n=153). 277 patients (144 assigned the light mask and 133 the sham mask) contributed to the mixed-effects model over time, including 246 patients with OCT data at 24 months. The change in maximum retinal thickness at 24 months did not differ between treatment groups (mean change -9·2 μm [SE 2·5] for the light mask vs -12·9 μm [SE 2·9] for the sham mask; adjusted mean difference -0·65 μm, 95% CI -6·90 to 5·59; p=0·84). Median compliance with wearing the light mask at 24 months was 19·5% (IQR 1·9-51·6). No serious adverse events were related to either mask. The most frequent adverse events related to the assigned treatment were discomfort on the eyes (14 with the light mask vs seven with the sham mask), painful, sticky, or

  11. Nutrient intakes and iron and vitamin D status differ depending on main milk consumed by UK children aged 12-18 months - secondary analysis from the Diet and Nutrition Survey of Infants and Young Children.

    Science.gov (United States)

    Sidnell, Anne; Pigat, Sandrine; Gibson, Sigrid; O'Connor, Rosalyn; Connolly, Aileen; Sterecka, Sylwia; Stephen, Alison M

    2016-01-01

    Nutrition in the second year is important as this is a period of rapid growth and development. Milk is a major food for young children and this analysis evaluated the impact of the type of milk consumed on nutrient intakes and nutritional status. Data from the Diet and Nutrition Survey of Infants and Young Children were used to investigate the intakes of key nutrients, and Fe and vitamin D status, of children aged 12-18 months, not breastfed, and consuming >400 g/d fortified milk (n 139) or >400 g/d of whole cows' milk (n 404). Blood samples from eligible children for measurement of Hb (n 113), serum ferritin and plasma 25-hydroxyvitamin D (25(OH)D) concentrations (n 105) were available for approximately 20 % of children. Unpaired Mann-Whitney tests were used to compare nutrient intakes and status between consumers of fortified and cows' milk. Mean daily total dietary intakes of Fe, Zn, vitamin A and vitamin D were significantly higher in the fortified milk group. Mean daily total dietary intakes of energy, protein, Ca, iodine, Na and saturated fat were significantly higher in the cows' milk group. Hb was not different between groups. The fortified milk group had significantly higher serum ferritin (P = 0·049) and plasma 25(OH)D (P = 0·014). This analysis demonstrates significantly different nutrient intakes and status between infants consuming >400 g/d fortified milk v. those consuming >400 g/d whole cows' milk. These results indicate that fortified milks can play a significant role in improving the quality of young children's diets in their second year of life.

  12. Effects of progressive resistance training combined with a protein-enriched lean red meat diet on health-related quality of life in elderly women: secondary analysis of a 4-month cluster randomised controlled trial.

    Science.gov (United States)

    Torres, Susan J; Robinson, Sian; Orellana, Liliana; O'Connell, Stella L; Grimes, Carley A; Mundell, Niamh L; Dunstan, David W; Nowson, Caryl A; Daly, Robin M

    2017-06-01

    Resistance training (RT) and increased dietary protein are recommended to attenuate age-related muscle loss in the elderly. This study examined the effect of a lean red meat protein-enriched diet combined with progressive resistance training (RT+Meat) on health-related quality of life (HR-QoL) in elderly women. In this 4-month cluster randomised controlled trial, 100 women aged 60-90 years (mean 73 years) from self-care retirement villages participated in RT twice a week and were allocated either 160 g/d (cooked) lean red meat consumed across 2 meals/d, 6 d/week or ≥1 serving/d (25-30 g) carbohydrates (control group, CRT). HR-QoL (SF-36 Health Survey questionnaire), lower limb maximum muscle strength and lean tissue mass (LTM) (dual-energy X-ray absorptiometry) were assessed at baseline and 4 months. In all, ninety-one women (91 %) completed the study (RT+Meat (n 48); CRT (n 43)). Mean protein intake was greater in RT+Meat than CRT throughout the study (1·3 (sd 0·3) v. 1·1 (sd 0·3) g/kg per d, P<0·05). Exercise compliance (74 %) was not different between groups. After 4 months there was a significant net benefit in the RT+Meat compared with CRT group for overall HR-QoL and the physical component summary (PCS) score (P<0·01), but there were no changes in either group in the mental component summary (MCS) score. Changes in lower limb muscle strength, but not LTM, were positively associated with changes in overall HR-QoL (muscle strength, β: 2·2 (95 % CI 0·1, 4·3), P<0·05). In conclusion, a combination of RT and increased dietary protein led to greater net benefits in overall HR-QoL in elderly women compared with RT alone, which was because of greater improvements in PCS rather than MCS.

  13. Status of Progress Made Toward Preliminary Design Concepts for the Inventory in Select Media for DOE-Managed HLW/SNF

    Energy Technology Data Exchange (ETDEWEB)

    Matteo, Edward N. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Hardin, Ernest L. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Hadgu, Teklu [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Park, Heeho Daniel [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Rigali, Mark J. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Jove-Colon, Carlos F. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States)

    2016-09-30

    As the title suggests, this report provides a summary of the status and progress for the Preliminary Design Concepts Work Package. Described herein are design concepts and thermal analysis for crystalline and salt host media. The report concludes that thermal management of defense waste, including the relatively small subset of high thermal output waste packages, is readily achievable. Another important conclusion pertains to engineering feasibility, and design concepts presented herein are based upon established and existing elements and/or designs. The multipack configuration options for the crystalline host media pose the greatest engineering challenges, as these designs involve large, heavy waste packages that pose specific challenges with respect to handling and emplacement. Defense-related Spent Nuclear Fuel (DSNF) presents issues for post-closure criticality control, and a key recommendation made herein relates to the need for special packaging design that includes neutron-absorbing material for the DSNF. Lastly, this report finds that the preliminary design options discussed are tenable for operational and post-closure safety, owing to the fact that these concepts have been derived from other published and well-studied repository designs.

  14. CO2 elevation improves photosynthetic performance in progressive warming environment in white birch seedlings [v1; ref status: indexed, http://f1000r.es/up

    Directory of Open Access Journals (Sweden)

    Shouren Zhang

    2013-01-01

    Full Text Available White birch (Betula paperifera Mash seedlings were exposed to progressively warming in greenhouses under ambient and elevated CO2 concentrations for 5 months to explore boreal tree species’ potential capacity to acclimate to global climate warming and CO2 elevation. In situ foliar gas exchange, in vivo carboxylation characteristics and chlorophyll fluorescence were measured at temperatures of 26oC and 37oC. Elevated CO2 significantly increased net photosynthetic rate (Pn at both measurement temperatures, and Pn at 37oC was higher than that at 26oC under elevated CO2. Stomatal conductance (gs was lower at 37oC than at 26oC, while transpiration rate (E was higher at 37oC than that at 26oC. Elevated CO2 significantly increased instantaneous water-use efficiency (WUE at both 26oC and 37oC, but WUE was markedly enhanced at 37oC under elevated CO2. The effect of temperature on maximal carboxylation rate (Vcmax, PAR-saturated electron transport rate (Jmax and triose phosphate utilization (TPU varied with CO2, and the Vcmax and Jmax were significantly higher at 37oC than at 26oC under elevated CO2. However, there were no significant interactive effects of CO2 and temperature on TPU. The actual photochemical efficiency of PSII (DF/ Fm’, total photosynthetic linear electron transport rate through PSII (JT and the partitioning of JT to carboxylation (Jc were higher at 37oC than at 26oC under elevated CO2. Elevated CO2 significantly suppressed the partitioning of JT to oxygenation (Jo/JT. The data suggest that the CO2 elevation and progressive warming greatly enhanced photosynthesis in white birch seedlings in an interactive fashion.

  15. Effects of a 12-month task-specific balance training on the balance status of stroke survivors with and without cognitive impairments in Selected Hospitals in Nnewi, Anambra State, Nigeria.

    Science.gov (United States)

    Okonkwo, Uchenna Prosper; Ibeneme, Sam Chidi; Ihegihu, Ebere Yvonne; Egwuonwu, Afamefuna Victor; Ezema, Charles Ikechukwu; Maruf, Fatai Adesina

    2018-05-02

    Stroke results in varying levels of physical disabilities that may adversely impact balance with increased tendency to falls. This may intensify with cognitive impairments (CI), and impede functional recovery. Therefore, task-specific balance training (TSBT), which presents versatile task-specific training options that matches varied individual needs, was explored as a beneficial rehabilitation regime for stroke survivors with and without CI. It was hypothesized that there will be no significant difference in the balance control measures in stroke survivors with and without CI after a 12-month TSBT. To determine if TSBT will have comparable beneficial effects on the balance control status of sub-acute ischemic stroke survivors with CI and without CI. One hundred of 143 available sub-acute first ever ischemic stroke survivors were recruited using convenience sampling technique in a quasi-experimental study. They were later assigned into the cognitive impaired group (CIG) and non-cognitive impaired group (NCIG), respectively, based on the baseline presence or absence of CI, after screening with the mini-mental examination (MMSE) tool. With the help of four trained research assistants, TSBT was applied to each group, thrice times a week, 60 mins per session, for 12 months. Their balance was measured as Bergs Balance scores (BBS) at baseline, 4th, 8th, and 12th month intervals. Data were analyzed statistically using Kruskal Wallis test, and repeated measure ANOVA, at p balance control of CIG with large effect size of 0.69 after 12 months of TSBT. There was also significant improvement across time points in the balance control of NCIG with large effect size of 0.544 after 12 months of TSBT. There was no significant difference between the improvement in CIG and NCIG after 8th and 12th months of TSBT.  Within the groups, a 12-month TSBT intervention significantly improved balance control, respectively, but with broader effects in the

  16. Effects of a large-scale micronutrient powder and young child feeding education program on the micronutrient status of children 6-24 months of age in the Kyrgyz Republic.

    Science.gov (United States)

    Serdula, M K; Lundeen, E; Nichols, E K; Imanalieva, C; Minbaev, M; Mamyrbaeva, T; Timmer, A; Aburto, N J

    2013-07-01

    To combat iron and other micronutrient deficiencies, the Ministry of Health of the Kyrgyz Republic launched a regional Infant and Young Child Nutrition (IYCN) program in 2009, which included promotion of home fortification with micronutrient powder (MNP) containing iron (12.5 mg elemental iron), vitamin A (300 μg) and other micronutrients. Every 2 months children aged 6-24 months were provided 30 sachets to be taken on a flexible schedule. The objective was to assess biochemical indicators of iron and vitamin A status among children aged 6-24 months at the baseline and follow-up surveys. Cross-sectional representative cluster surveys were conducted in 2008 (n=571 children) and 2010 (n=541). Data collected included measurement of hemoglobin, serum ferritin, soluble transferrin receptor (sTfR), retinol-binding protein, C-reactive protein (CRP) and α1-glycoprotein acid (AGP). Among all children, declines were observed in the prevalence of: anemia, 50.6% versus 43.8% (P=0.05); total iron deficiency (either low ferritin or high sTfR), 77.3% versus 63.7% (P<0.01); and iron deficiency anemia, 45.5% versus 33.4% (P<0.01). Among children without inflammation as measured by CRP and AGP, similar declines were observed, but only declines in total iron deficiency and iron deficiency anemia reached statistical significance. Among all children and those without inflammation, the prevalence of vitamin A deficiency remained the same. One year after the introduction of home fortification with MNP, within a larger IYCN program, the prevalence of anemia, iron deficiency and iron deficiency anemia declined, but vitamin A deficiency remained unchanged.

  17. Crevicular fluid biomarkers and periodontal disease progression.

    Science.gov (United States)

    Kinney, Janet S; Morelli, Thiago; Oh, Min; Braun, Thomas M; Ramseier, Christoph A; Sugai, Jim V; Giannobile, William V

    2014-02-01

    Assess the ability of a panel of gingival crevicular fluid (GCF) biomarkers as predictors of periodontal disease progression (PDP). In this study, 100 individuals participated in a 12-month longitudinal investigation and were categorized into four groups according to their periodontal status. GCF, clinical parameters and saliva were collected bi-monthly. Subgingival plaque and serum were collected bi-annually. For 6 months, no periodontal treatment was provided. At 6 months, patients received periodontal therapy and continued participation from 6 to 12 months. GCF samples were analysed by ELISA for MMP-8, MMP-9, Osteoprotegerin, C-reactive Protein and IL-1β. Differences in median levels of GCF biomarkers were compared between stable and progressing participants using Wilcoxon Rank Sum test (p = 0.05). Clustering algorithm was used to evaluate the ability of oral biomarkers to classify patients as either stable or progressing. Eighty-three individuals completed the 6-month monitoring phase. With the exception of GCF C-reactive protein, all biomarkers were significantly higher in the PDP group compared to stable patients. Clustering analysis showed highest sensitivity levels when biofilm pathogens and GCF biomarkers were combined with clinical measures, 74% (95% CI = 61, 86). Signature of GCF fluid-derived biomarkers combined with pathogens and clinical measures provides a sensitive measure for discrimination of PDP (ClinicalTrials.gov NCT00277745). © 2013 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

  18. The thyroid status of children and adolescents in Fukushima Prefecture examined during 20-30 months after the Fukushima nuclear power plant disaster: a cross-sectional, observational study.

    Directory of Open Access Journals (Sweden)

    Hajime Watanobe

    Full Text Available BACKGROUND: A possible increase in thyroid cancer in the young represents the most critical health problem to be considered after the nuclear accident in Fukushima, Japan (March 2011, which is an important lesson from the Chernobyl disaster (April 1986. Although it was reported that childhood thyroid cancer had started to increase 3-5 yr after the Chernobyl accident, we speculate that the actual period of latency might have been shorter than reported, considering the delay in initiating thyroid surveillance in the then Soviet Union and also the lower quality of ultrasonographic testing in the 1980s. Our primary objectives in the present study were to identify any possible thyroid abnormality in young Fukushima citizens at a relatively early timepoint (20-30 months after the accident, and also to strive to find a possible relationship among thyroid ultrasonographic findings, thyroid-relevant biochemical markers, and iodine-131 ground deposition in the locations of residence where they stayed during very early days after the accident. METHODS AND FINDINGS: This is a cross-sectional study. We targeted the Fukushima residents who were 18 yr old or younger (including fetuses at the time of the accident. Our examinations comprised a questionnaire, thyroid ultrasonography, thyroid-related blood tests, and urinary iodine measurement. We analyzed a possible relationship among thyroid ultrasonographic findings (1,137 subjects, serum hormonal data (731 subjects, urinary iodine concentrations (770 subjects, and iodine-131 ground deposition (1,137 subjects. We did not find any significant relationship among these indicators, and no participant was diagnosed to contract thyroid cancer. CONCLUSIONS: At the timepoint of 20-30 months after the accident, we did not confirm any discernible deleterious effects of the emitted radioactivity on the thyroid of young Fukushima residents. This is the first report in English detailing the thyroid status of young Fukushima

  19. The Thyroid Status of Children and Adolescents in Fukushima Prefecture Examined during 20–30 Months after the Fukushima Nuclear Power Plant Disaster: A Cross-Sectional, Observational Study

    Science.gov (United States)

    Watanobe, Hajime; Furutani, Tomoyuki; Nihei, Masahiko; Sakuma, Yu; Yanai, Rie; Takahashi, Miyuki; Sato, Hideo; Sagawa, Fumihiko

    2014-01-01

    Background A possible increase in thyroid cancer in the young represents the most critical health problem to be considered after the nuclear accident in Fukushima, Japan (March 2011), which is an important lesson from the Chernobyl disaster (April 1986). Although it was reported that childhood thyroid cancer had started to increase 3–5 yr after the Chernobyl accident, we speculate that the actual period of latency might have been shorter than reported, considering the delay in initiating thyroid surveillance in the then Soviet Union and also the lower quality of ultrasonographic testing in the 1980s. Our primary objectives in the present study were to identify any possible thyroid abnormality in young Fukushima citizens at a relatively early timepoint (20–30 months) after the accident, and also to strive to find a possible relationship among thyroid ultrasonographic findings, thyroid-relevant biochemical markers, and iodine-131 ground deposition in the locations of residence where they stayed during very early days after the accident. Methods and Findings This is a cross-sectional study. We targeted the Fukushima residents who were 18 yr old or younger (including fetuses) at the time of the accident. Our examinations comprised a questionnaire, thyroid ultrasonography, thyroid-related blood tests, and urinary iodine measurement. We analyzed a possible relationship among thyroid ultrasonographic findings (1,137 subjects), serum hormonal data (731 subjects), urinary iodine concentrations (770 subjects), and iodine-131 ground deposition (1,137 subjects). We did not find any significant relationship among these indicators, and no participant was diagnosed to contract thyroid cancer. Conclusions At the timepoint of 20–30 months after the accident, we did not confirm any discernible deleterious effects of the emitted radioactivity on the thyroid of young Fukushima residents. This is the first report in English detailing the thyroid status of young Fukushima

  20. 2018 Status Report of NP04 (ProtoDUNE-SP)

    CERN Document Server

    Touramanis, C

    2018-01-01

    The NP04 Liquid Argon TPC has been constructed in the CERN Neutrino Facility and is in final preparation for taking beam data before the end of the current beam period at CERN. Progress in the last twelve months, current status, and plans are presented.

  1. Severe events in the first 6 months of life in a cohort of HIV-unexposed infants from South Africa: effects of low birthweight and breastfeeding status.

    Science.gov (United States)

    Doherty, Tanya; Jackson, Debra; Swanevelder, Sonja; Lombard, Carl; Engebretsen, Ingunn M S; Tylleskär, Thorkild; Goga, Ameena; Ekström, Eva-Charlotte; Sanders, David

    2014-10-01

    To report on risk factors for severe events (hospitalisation or infant death) within the first half of infancy amongst HIV-unexposed infants in South Africa. South African data from the multisite community-based cluster-randomised trial PROMISE EBF promoting exclusive breastfeeding in three sub-Saharan countries from 2006 to 2008 were used. The South African sites were Paarl in the Western Cape Province, and Umlazi and Rietvlei in KwaZulu-Natal. This analysis included 964 HIV-negative mother-infant pairs. Data on severe events and infant feeding practices were collected at 3, 6, 12 and 24 weeks post-partum. We used a stratified extended Cox model to examine the association between the time to the severe event and covariates including birthweight, with breastfeeding status as a time-dependent covariate. Seventy infants (7%) experienced a severe event. The median age at first hospitalisation was 8 weeks, and the two main reasons for hospitalisation were cough and difficult breathing followed by diarrhoea. Stopping breastfeeding before 6 months (HR 2.4; 95% CI 1.2-5.1) and low birthweight (HR 2.4; 95% CI 1.3-4.3) were found to increase the risk of a severe event, whilst maternal completion of high school education was protective (HR 0.3; 95% CI 0.1-0.7). A strengthened primary healthcare system incorporating promotion of breastfeeding and appropriate caring practices for low birthweight infants (such as kangaroo mother care) are critical. Given the leading reasons for hospitalisation, early administration of oral rehydration therapy and treatment of suspected pneumonia are key interventions needed to prevent hospitalisation in young infants. © 2014 The Authors. Tropical Medicine & International Health Published by John Wiley & Sons Ltd.

  2. Never, non-daily, and daily smoking status and progression to daily cigarette smoking as correlates of major depressive episode in a national sample of youth: Results from the National Survey of Drug Use and Health 2013 to 2015.

    Science.gov (United States)

    Cohn, Amy M

    2018-09-01

    Cigarette smoking is associated with depression, and new initiates who progress more quickly to daily smoking may be at enhanced risk. In a nationally representative sample of youth, this study examined the association between daily, non-daily, and never smoking with past-year and lifetime major depressive episode (MDE) and, among daily smokers, whether faster progression to daily smoking was associated with increased MDE risk. Data were from n = 44,921 youth aged 12-17 in the 2013-2015 National Survey on Drug Use and Health. Weighted adjusted multivariable logistic regression models were used to examine the association of smoking status (daily, non-daily, never) with lifetime and past-year MDE, and the association between progression from cigarette trial to daily smoking with MDE outcomes among daily smokers. Daily and non-daily smokers had similar rates of lifetime and past-year MDE; rates of MDE were approximately 50% lower among never smokers. Compared to never smokers, adjusted models showed that non-daily smokers had a higher risk of past-year and lifetime MDE, while daily smokers had a higher risk of past-year but not lifetime MDE. Daily smoking youth who progressed more quickly from cigarette trial to daily use had an increased risk of both lifetime and past-year MDE. Prevention programs should target factors associated with the shift from cigarette experimentation to regular use to curb deleterious consequences of use. Copyright © 2018. Published by Elsevier Ltd.

  3. Examining the Relationships among Mathematics Coaches and Specialists, Student Achievement, and Disability Status: A Multilevel Analysis Using National Assessment of Educational Progress Data

    Science.gov (United States)

    Harbour, Kristin E.; Adelson, Jill L.; Pittard, Caroline M.; Karp, Karen S.

    2018-01-01

    Using restricted-use data from the 2011 National Assessment of Educational Progress mathematics assessment, the current study examined the relationship between the presence of elementary mathematics coaches and specialists (MCSs) and the mathematics achievement of more than 190,000 fourth-grade students in more than 7,400 schools nationwide. In…

  4. Multinational study in children and adolescents with newly diagnosed type 1 diabetes: association of age, ketoacidosis, HLA status, and autoantibodies on residual beta-cell function and glycemic control 12 months after diagnosis

    DEFF Research Database (Denmark)

    Mortensen, H.B.; Swift, P.G.F.; Holl, R.W.

    2010-01-01

    .005), and by stimulated C-peptide (p IA; p = 0.02) and glutamic acid decarboxylase antibodies (GADA; p = 0.0004) at 1 month. HbA1c at 12 months was predicted by HbA1c at diagnosis (p ... (p = 0.002). Conclusions: Younger age, ketoacidosis at diagnosis, and IA and GADA 1 month after diagnosis were the strongest explanatory factors for residual beta-cell function at 12 months. Glycemic control at 12 months was influenced predominantly by ethnicity, HbA1c at diagnosis, and GADA at 1......Objective: To identify predictors of residual beta-cell function and glycemic control during the first 12 months after the diagnosis of type 1 diabetes (T1D). Subjects and Methods: Clinical information and blood samples were collected from 275 children. HbA1c, antibodies, HLA typing and mixed meal...

  5. The effect of the World Kidney Day campaign on the awareness of chronic kidney disease and the status of risk factors for cardiovascular disease and renal progression.

    Science.gov (United States)

    Chin, Ho Jun; Ahn, Jeong Myeong; Na, Ki Young; Chae, Dong-Wan; Lee, Tae Woo; Heo, Nam Joo; Kim, Suhnggwon

    2010-02-01

    Chronic kidney disease (CKD) is a worldwide problem. We describe the trends in CKD awareness before and after the World Kidney Day (WKD) campaign and the impact of the WKD campaign in increasing awareness and appropriate management of the risk factors for cardiovascular disease and renal progression. We selected 57 718 people who had undergone a routine health check-up. The average CKD awareness was 3.1% (95% CI: 2.6-3.7%) and was increased with progressing CKD stage. The awareness was increased from 1.1% before the WKD campaign to 5.8% after the campaign (P campaign had a positive impact on the awareness and control of risk factors in CKD subjects but the absolute frequency of CKD awareness still remains undesirable in Korea. We need new campaign strategies to publicize the importance of early diagnosis and appropriate management of CKD.

  6. Petroleum Supply Monthly

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-02-01

    The Petroleum Supply Monthly (PSM) is one of a family of four publications produced by the Petroleum Supply Division within the Energy Information Administration (EIA) reflecting different levels of data timeliness and completeness. The other publications are the Weekly Petroleum Status Report (WPSR), the Winter Fuels Report, and the Petroleum Supply Annual (PSA). Data presented in the PSM describe the supply and disposition of petroleum products in the United States and major U.S. geographic regions. The data series describe production, imports and exports, inter-Petroleum Administration for Defense (PAD) District movements, and inventories by the primary suppliers of petroleum products in the United States (50 States and the District of Columbia). The reporting universe includes those petroleum sectors in primary supply. Included are: petroleum refiners, motor gasoline blenders, operators of natural gas processing plants and fractionators, inter-PAD transporters, importers, and major inventory holders of petroleum products and crude oil. When aggregated, the data reported by these sectors approximately represent the consumption of petroleum products in the United States. Data presented in the PSM are divided into two sections: Summary Statistics and Detailed Statistics.

  7. Petroleum supply monthly

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1995-10-01

    The Petroleum Supply Monthly (PSM) is one of a family of four publications produced by the Petroleum Supply Division within the Energy Information Administration (EIA) reflecting different levels of data timeliness and completeness. The other publications are the Weekly Petroleum Status Report (WPSR), the Winter Fuels Report, and the Petroleum Supply Annual (PSA). Data presented in the PSM describe the supply and disposition of petroleum products in the United States and major US geographic regions. The data series describe production, imports and exports, inter-Petroleum Administration for Defense (PAD) District movements, and inventories by the primary suppliers of petroleum products in the United States (50 States and the District of Columbia). The reporting universe includes those petroleum sectors in primary supply. Included are: petroleum refiners, motor gasoline blends, operators of natural gas processing plants and fractionators, inter-PAD transporters, importers, and major inventory holders of petroleum products and crude oil. When aggregated, the data reported by these sectors approximately represent the consumption of petroleum products in the United States.

  8. Strong association between serological status and probability of progression to clinical visceral leishmaniasis in prospective cohort studies in India and Nepal.

    Directory of Open Access Journals (Sweden)

    Epco Hasker

    Full Text Available Asymptomatic persons infected with the parasites causing visceral leishmaniasis (VL usually outnumber clinically apparent cases by a ratio of 4-10 to 1. We assessed the risk of progression from infection to disease as a function of DAT and rK39 serological titers.We used available data on four cohorts from villages in India and Nepal that are highly endemic for Leishmania donovani. In each cohort two serosurveys had been conducted. Based on results of initial surveys, subjects were classified as seronegative, moderately seropositive or strongly seropositive using both DAT and rK39. Based on the combination of first and second survey results we identified seroconvertors for both markers. Seroconvertors were subdivided in high and low titer convertors. Subjects were followed up for at least one year following the second survey. Incident VL cases were recorded and verified.We assessed a total of 32,529 enrolled subjects, for a total follow-up time of 72,169 person years. Altogether 235 incident VL cases were documented. The probability of progression to disease was strongly associated with initial serostatus and with seroconversion; this was particularly the case for those with high titers and most prominently among seroconvertors. For high titer DAT convertors the hazard ratio reached as high as 97.4 when compared to non-convertors. The strengths of the associations varied between cohorts and between markers but similar trends were observed between the four cohorts and the two markers.There is a strongly increased risk of progressing to disease among DAT and/or rK39 seropositives with high titers. The options for prophylactic treatment for this group merit further investigation, as it could be of clinical benefit if it prevents progression to disease. Prophylactic treatment might also have a public health benefit if it can be corroborated that these asymptomatically infected individuals are infectious for sand flies.

  9. Effect of 3 months of progressive high-load strength training in patients with rotator cuff tendinopathy: Primary results from the double-blind, randomised, controlled Rotator Cuff Tendinopathy Exercise (RoCTEx) trial

    DEFF Research Database (Denmark)

    Ingwersen, Kim Gordon; Jensen, Steen Lund; Sørensen, Lilli

    2017-01-01

    BACKGROUND: Progressive high-load exercise (PHLE) has led to positive clinical results in patients with patellar and Achilles tendinopathy. However, its effects on rotator cuff tendinopathy still need to be investigated. PURPOSE: To assess the clinical effects of PHLE versus low-load exercise (LLE......) among patients with rotator cuff tendinopathy. STUDY DESIGN: Randomized controlled trial; Level of evidence, 1. METHODS: Patients with rotator cuff tendinopathy were recruited and randomized to 12 weeks of PHLE or LLE, stratified for concomitant administration of corticosteroid injection. The primary...... benefit from PHLE over traditional LLE among patients with rotator cuff tendinopathy. Further investigation of the possible interaction between exercise type and corticosteroid injection is needed to establish optimal and potentially synergistic combinations of these 2 factors. REGISTRATION: NCT01984203...

  10. Hanford Works monthly report, October 1950

    Energy Technology Data Exchange (ETDEWEB)

    Prout, G.R.

    1950-11-20

    This is a progress report of the production reactors on the Hanford Reservation for the month of October 1950. This report takes each division (e.g., manufacturing, medical, accounting, occupational safety, security, reactor operations, etc.) of the site and summarizes its accomplishments and employee relations for that month.

  11. Hanford Works monthly report, December 1950

    Energy Technology Data Exchange (ETDEWEB)

    Prout, G.R.

    1951-01-22

    This is a progress report of the production reactors on the Hanford Reservation for the month of December 1950. This report takes each division (e.g., manufacturing, medical, accounting, occupational safety, security, reactor operations, etc.) of the site and summarizes its accomplishments and employee relations for that month.

  12. Hanford Works monthly report, May 1950

    Energy Technology Data Exchange (ETDEWEB)

    Prout, G.R.

    1950-06-20

    This is a progress report of the production reactors on the Hanford Reservation for the month of May 1950. This report takes each division (e.g., manufacturing, medical, accounting, occupational safety, security, reactor operations, etc.) of the site and summarizes its accomplishments and employee relations for that month.

  13. Hanford Works monthly report, July 1950

    Energy Technology Data Exchange (ETDEWEB)

    Prout, G.R.

    1950-08-18

    This is a progress report of the production reactors on the Hanford Reservation for the month of July 1950. This report takes each division (e.g., manufacturing, medical, accounting, occupational safety, security, reactor operations, etc.) of the site and summarizes its accomplishments and employee relations for that month.

  14. Hanford Works monthly report, March 1952

    Energy Technology Data Exchange (ETDEWEB)

    Prout, G.R.

    1952-04-18

    This is a progress report of the production reactors on the Hanford Reservation for the month of April 1952. This report takes each division (e.g., manufacturing, medical, accounting, occupational safety, security, reactor operations, etc.) of the site and summarizes its accomplishments and employee relations for that month.

  15. Hanford Works monthly report, April 1952

    Energy Technology Data Exchange (ETDEWEB)

    Prout, G.R.

    1952-05-20

    This is a progress report of the production reactors on the Hanford Reservation for the month of April 1952. This report takes each division (e.g., manufacturing, medical, accounting, occupational safety, security, reactor operations, etc.) of the site and summarizes its accomplishments and employee relations for that month.

  16. Hanford Works monthly report, July 1952

    Energy Technology Data Exchange (ETDEWEB)

    Prout, G.R.

    1952-08-15

    This is a progress report of the production reactors on the Hanford Reservation for the month of July 1952. This report takes each division (e.g., manufacturing, medical, accounting, occupational safety, security, reactor operations, etc.) of the site and summarizes its accomplishments and employee relations for that month.

  17. Hanford Works monthly report, January 1952

    Energy Technology Data Exchange (ETDEWEB)

    Prout, G.R.

    1952-02-21

    This is a progress report of the production reactors on the Hanford Reservation for the month of January 1952. This report takes each division (e.g., manufacturing, medical, accounting, occupational safety, security, reactor operations, etc.) of the site and summarizes its accomplishments and employee relations for that month.

  18. Hanford Works monthly report, September 1950

    Energy Technology Data Exchange (ETDEWEB)

    Prout, G.R.

    1950-10-20

    This is a progress report of the production reactors on the Hanford Reservation for the month of September 1950. This report takes each division (e.g., manufacturing, medical, accounting, occupational safety, security, reactor operations, etc.) of the site and summarizes its accomplishments and employee relations for that month.

  19. Hanford Works monthly report, July 1951

    Energy Technology Data Exchange (ETDEWEB)

    Prout, G.R.

    1951-08-24

    This is a progress report of the production reactors on the Hanford Reservation for the month of July 1951. This report takes each division (e.g., manufacturing, medical, accounting, occupational safety, security, reactor operations, etc.) of the site and summarizes its accomplishments and employee relations for that month.

  20. Hanford Works monthly report, March 1951

    Energy Technology Data Exchange (ETDEWEB)

    Prout, G.R.

    1951-04-20

    This is a progress report of the production reactors on the Hanford Reservation for the month of March 1951. This report takes each division (e.g., manufacturing, medical, accounting, occupational safety, security, reactor operations, etc.) of the site and summarizes its accomplishments and employee relations for that month.

  1. Hanford Works monthly report, June 1951

    Energy Technology Data Exchange (ETDEWEB)

    1951-07-20

    This is a progress report of the production on the Hanford Reservation for the month of June 1951. This report takes each division (e.g., manufacturing, medical, accounting, occupational safety, security, reactor operations, etc.) of the site and summarizes its accomplishments and employee relations for that month.

  2. Hanford works monthly report, September 1951

    Energy Technology Data Exchange (ETDEWEB)

    Prout, G.R.

    1951-10-19

    This is a progress report of the production reactors on the Hanford Reservation for the month of September 1951. This report takes each division (e.g., manufacturing, medical, accounting, occupational safety, security, reactor operations, etc.) of the site and summarizes its accomplishments and employee relations for that month.

  3. Hanford Works monthly report, May 1951

    Energy Technology Data Exchange (ETDEWEB)

    Prout, G.R.

    1951-06-21

    This is a progress report of the production reactors on the Hanford Reservation for the month of May 1951. This report takes each division (e.g., manufacturing, medical, accounting, occupational safety, security, reactor operations, etc.) of the site and summarizes its accomplishments and employee relations for that month.

  4. Hanford Works monthly report, June 1950

    Energy Technology Data Exchange (ETDEWEB)

    Prout, G.R.

    1950-07-20

    This is a progress report of the production reactors on the Hanford Reservation for the month of June 1950. This report takes each division (e.g., manufacturing, medical, accounting, occupational safety, security, reactor operations, etc.) of the site and summarizes its accomplishments and employee relations for that month.

  5. Hanford Works monthly report, November 1951

    Energy Technology Data Exchange (ETDEWEB)

    Prout, G.R.

    1951-12-21

    This is a progress report of the production reactors on the Hanford Reservation for the month of November 1951. This report takes each division (e.g., manufacturing, medical, accounting, occupational safety, security, reactor operations, etc.) of the site and summarizes its accomplishments and employee relations for that month.

  6. Hanford Works monthly report, August 1951

    Energy Technology Data Exchange (ETDEWEB)

    1951-09-24

    This is a progress report of the production reactors on the Hanford Reservation for the month of August 1951. This report takes each division (e.g., manufacturing, medical, accounting, occupational safety, security, reactor operations, etc.) of the site and summarizes its accomplishments and employee relations for that month.

  7. Hanford Works monthly report, August 1950

    Energy Technology Data Exchange (ETDEWEB)

    Prout, G.R.

    1950-09-18

    This is a progress report of the production reactors on the Hanford Reservation for the month of August 1950. This report takes each division (e.g. manufacturing, medical, accounting, occupational safety, security, reactor operations, etc.) of the site and summarizes its accomplishments and employee relations for that month.

  8. Hanford Works monthly report, November 1950

    Energy Technology Data Exchange (ETDEWEB)

    Prout, G.R.

    1950-12-20

    This is a progress report of the production reactors on the Hanford Reservation for the month of November 1950. This report takes each division (e.g. manufacturing, medical, accounting, occupational safety, security, reactor operations, etc.) of the site and summarizes its accomplishments and employee relations for that month.

  9. Hanford Works monthly report, February 1951

    Energy Technology Data Exchange (ETDEWEB)

    Prout, G.R.

    1951-03-20

    This is a progress report of the production on the Hanford Reservation for the month of February 1951. This report takes each division (e.g., manufacturing, medical, accounting, occupational safety, security, reactor operations, etc.) of the site and summarizes its accomplishments and employee relations for that month.

  10. Hanford Works monthly report, December 1951

    Energy Technology Data Exchange (ETDEWEB)

    Prout, G.R.

    1952-01-22

    This is a progress report of the production reactors on the Hanford Reservation for the month of December 1951. This report takes each division (e.g., manufacturing, medical, accounting, occupational safety, security, reactor operations, etc.) of the site and summarizes its accomplishments and employee relations for that month.

  11. Hanford Works monthly report, January 1951

    Energy Technology Data Exchange (ETDEWEB)

    Prout, G.R.

    1951-02-16

    This is a progress report of the production reactors on the Hanford Reservation for the month of January 1951. This report takes each division (e.g. manufacturing, medical, accounting, occupational safety, security, reactor operations, etc.) of the site and summarizes its accomplishments and employee relations for that month.

  12. Hanford Works monthly report, April 1951

    Energy Technology Data Exchange (ETDEWEB)

    Prout, G.R.

    1951-05-21

    This is a progress report of the production reactors on the Hanford Reservation for the month of April 1951. This report takes each division (e.g., manufacturing, medical, accounting, occupational safety, security, reactor operations, etc.) of the site and summarizes its accomplishments and employee relations for that month.

  13. Hanford Works monthly report, March 1949

    Energy Technology Data Exchange (ETDEWEB)

    Prout, G.R.

    1949-04-19

    This is a progress report of the production reactors on the Hanford Reservation for the month of March 1949. This report takes each division (e.g. manufacturing, medical, accounting, occupational safety, security, reactor operations, etc.) of the site and summarizes its accomplishments and employee relations for that month. (MB)

  14. Evaluation of using cyclocranes to support drilling & production of oil & gas in wetland areas. Sixth quarterly technical progress report, incorporating milestone schedule/status, October 1993--December 1993

    Energy Technology Data Exchange (ETDEWEB)

    Eggington, W.J.

    1994-04-01

    This report is a progress report on a planned program falling under wetlands area research related to drilling, production, and transportation of oil and gas resources. Specifically the planned program addresses an evaluation of using cyclocraft to transport drill rigs, mud, pipes and other materials and equipment in a cost effective and environmentally safe manner to support oil and gas drilling and production operations in wetland areas. During this period, task 5, subscale tests, and task 7, environmental impacts, were completed. Work was continued on task 10, technology transfer, and the preparation of the final report as part of task 11.

  15. The impact of HIV status, HIV disease progression, and post-traumatic stress symptoms on the health-related quality of life of Rwandan women genocide survivors.

    Science.gov (United States)

    Gard, Tracy L; Hoover, Donald R; Shi, Qiuhu; Cohen, Mardge H; Mutimura, Eugene; Adedimeji, Adebola A; Anastos, Kathryn

    2013-10-01

    We examined whether established associations between HIV disease and HIV disease progression on worse health-related quality of life (HQOL) were applicable to women with severe trauma histories, in this case Rwandan women genocide survivors, the majority of whom were HIV-infected. Additionally, this study attempted to clarify whether post-traumatic stress symptoms were uniquely associated with HQOL or confounded with depression. The Rwandan Women's Interassociation Study and Assessment was a longitudinal prospective study of HIV-infected and uninfected women. At study entry, 922 women (705 HIV+ and 217 HIV-) completed measures of symptoms of post-traumatic stress and HQOL as well as other demographic, clinical, and behavioral characteristics. Even after controlling for potential confounders and mediators, HIV+ women, in particular those with the lowest CD4 counts, scored significantly worse on HQOL and overall quality of life (QOL) than did HIV- women. Even after controlling for depression and HIV disease progression, women with more post-traumatic stress symptoms scored worse on HQOL and overall QOL than women with fewer post-traumatic stress symptoms. This study demonstrated that post-traumatic stress symptoms were independently associated with HQOL and overall QOL, independent of depression and other confounders or potential mediators. Future research should examine whether the long-term impact of treatment on physical and psychological symptoms of HIV and post-traumatic stress symptoms would generate improvement in HQOL.

  16. Progress and challenges in the computational prediction of gene function using networks [v1; ref status: indexed, http://f1000r.es/SqmJUM

    Directory of Open Access Journals (Sweden)

    Paul Pavlidis

    2012-09-01

    Full Text Available In this opinion piece, we attempt to unify recent arguments we have made that serious confounds affect the use of network data to predict and characterize gene function. The development of computational approaches to determine gene function is a major strand of computational genomics research. However, progress beyond using BLAST to transfer annotations has been surprisingly slow. We have previously argued that a large part of the reported success in using "guilt by association" in network data is due to the tendency of methods to simply assign new functions to already well-annotated genes. While such predictions will tend to be correct, they are generic; it is true, but not very helpful, that a gene with many functions is more likely to have any function. We have also presented evidence that much of the remaining performance in cross-validation cannot be usefully generalized to new predictions, making progressive improvement in analysis difficult to engineer. Here we summarize our findings about how these problems will affect network analysis, discuss some ongoing responses within the field to these issues, and consolidate some recommendations and speculation, which we hope will modestly increase the reliability and specificity of gene function prediction.

  17. Review of core technologies for development of 2G HTS NMR/MRI magnet: A status report of progress in Korea University

    Directory of Open Access Journals (Sweden)

    J.B. Song

    Full Text Available In this paper, we briefly review our recent progress on development of core technologies for 2G HTS NMR/MRI magnets at Korea University. To outperform the current state-of-art NMR/MRI magnet systems, we have developed the following technologies: 1 a REBCO-REBCO superconducting joint for operation of persistent current mode; 2 partial and grease-insulation winding techniques for self-protection of the HTS magnets; 3 pre-shimming to reduce the screening-current-induced-field; and 4 optimization of multi-width winding to minimize conductor consumption and volume of the HTS magnets. The test results demonstrated the feasibility of employing the developed techniques to achieve ultra-high-field and LHe-free 2G NMR/MRI magnets possessing self-protecting feature.

  18. Monthly Weather Review

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Supplements to the Monthly Weather Review publication. The Weather Bureau published the Monthly weather review Supplement irregularly from 1914 to 1949. The...

  19. Status of French electricity and natural gas retail markets. Report 2015-2016 Control. Energy retail markets: how does competition progress?

    International Nuclear Information System (INIS)

    2017-01-01

    This publication aims at making data and indicators available to provide a view on recent evolutions of electric power and natural gas retail markets in France. After a presentation of some key figures produced by a survey on the knowledge of French people about market opening, this report first addresses the electric power market. It proposes an assessment of the electricity market opening by the end of December 2015: number of actors, number of large and non residential sites submitted to regulated prices, development of alternate providers, control of EDF commitments regarding long term contracts, assessment of competition intensity, follow-up of key processes and power cuts for non-payment. The report also proposes an analysis of the status of the power market on the territory of the main local distribution companies, and an analysis of electric power offers proposed to consumers (regulated prices, retail prices). The second part of the report addresses the same issues, but regarding the gas retail market

  20. Status and habitat requirements of white sturgeon populations in the Columbia River downstream from McNary Dam, annual progress report, July 1986 - March 1987.; ANNUAL

    International Nuclear Information System (INIS)

    Oregon Department of Fish and Wildlife; Washington Department of Fisheries

    1987-01-01

    Measure 804(e)(8) of the Northwest Power Planning Council (NPPC) Fish and Wildlife Program states that Bonneville Power Administration (BPA) ''shall fund research to determine the impacts of development and operation of the hydroelectric power system on sturgeon in the Columbia River Basin...'' In June 1985, BPA sponsored a workshop to define and list in priority order research needs in the basin (Fickeisen 1985a). In December 1985, BPA submitted a research program implementation plan (Fickeisen 1985b) to the NPPC. The purpose of the plan is to provide guidance for conducting research necessary to address four objectives identified by regional fishery interests for protecting, mitigating and enhancing white sturgeon populations in the Columbia River basin. The plan's objectives are: (1) Assess the current status of Columbia River basin white sturgeon stocks. (2) Provide the basis to evaluate the need for protection, mitigation and enhancement of white sturgeon in the Columbia River system. (3) Provide information that can be used to evaluate potential methods of protection, mitigation and enhancement of existing stocks. (4) Provide tools to assess the effectiveness of protection, mitigation and enhancement efforts

  1. The prevalence of the HPV 16 genome, integrated viral status and p53 genotype in cervical cancer population of north-eastern Hungary, the correlation with the established markers of tumour progression.

    Science.gov (United States)

    Hernádi, Zoltán; Sápy, Tamás; Krasznai, Zoárd T

    2004-03-15

    To evaluate the prevalence of the HPV 16 integrated status and the p53 genotype in cervical cancer in north-eastern Hungary and their correlation with the established prognostic factors. Parallel with the routine histological examination, Southern blot hybridisation and multiplex PCRs were used to detect type/physical state of HPV DNA in primary tumours and in regional lymph nodes combined with p53 genotyping of 83 patients. 46.9% (39/83) prevalence rate of HPV 16 genome was found. The frequency of viral integration (76.9% in primary tumours and 95.2% in regional lymph nodes) and that of the p53Arg homozygous genotype (64.1%) proved to be higher than reported from other parts of the world. The HPV 16 integration and the p53 genotype, failed to correlate with the FIGO stage and lymphatic spread. The prevalence of the integrated status of the HPV 16 genome combined with homozygous p53Arg genotype is relatively high in Hungary. These factors however failed to show a strong correlation with the established markers of tumour progression.

  2. Oral Supplementation of Parturient Mothers with Vitamin D and Its Effect on 25OHD Status of Exclusively Breastfed Infants at 6 Months of Age: A Double-Blind Randomized Placebo Controlled Trial.

    Science.gov (United States)

    Naik, Prasanna; Faridi, M M A; Batra, Prerna; Madhu, S V

    2017-12-01

    Exclusively breastfed infants are at increased risk of vitamin D deficiency and many lactating mothers have been found deficient in 25OHD stores. To compare serum vitamin D levels in exclusively breastfed infants at 6 months of age with or without oral supplementation of 600,000 IU of vitamin D3 to mothers in early postpartum period. Exclusively breastfeeding term parturient mothers were randomized 24-48 hours following delivery to receive either 600,000 IU of vitamin D3 (Cholecalciferol) over 10 days in a dose of 60,000 IU/day or placebo. 25OHD levels were measured by Radio Immuno Assay method at recruitment and after 6 months in all mothers and their infants. Urinary calcium and creatinine ratio was measured to monitor adverse effects of vitamin D3 in both mothers and infants at 14 weeks and 6 months of age. X-ray of both wrists in anteroposterior view and serum alkaline phosphatase of infants were done in both groups at 6 months of age to look for evidence of rickets. Maternal profile was similar in intervention (A) and control (B) groups. Mothers' serum 25OHD levels at recruitment were also similar being 16.2 ± 9.3 ng/mL in group A and 14.1 ± 7.1 ng/mL in group B. After 6 months, 25OHD levels were 40.3 ± 21.6 and 22.9 ± 20.1 ng/mL in group A and group B mothers (p ≤ 0.00), respectively. The serum 25OHD levels in cord blood were 9.9 ± 5.7 and 8.9 ± 5.1 ng/mL, respectively, in infants born to mothers in intervention and control groups (p = 0.433). At 6 months of age, the serum 25OHD levels significantly (p vitamin D3. Serum 25OHD levels of exclusively breastfed infants significantly rise at 6 months of age when their mothers are orally supplemented with 60,000 IU of vitamin D3 daily for 10 days in the early postpartum period in comparison to infants of vitamin D3 unsupplemented mothers.

  3. One year change of knee cartilage morphology in the first release of participants from the Osteoarthritis Initiative progression subcohort: association with sex, body mass index, symptoms and radiographic osteoarthritis status

    Science.gov (United States)

    Eckstein, F; Maschek, S; Wirth, W; Hudelmaier, M; Hitzl, W; Wyman, B; Nevitt, M; Hellio Le Graverand, M-P

    2010-01-01

    Objective The Osteoarthritis Initiative (OAI) is a multicentre study targeted at identifying biomarkers for evaluating the progression and risk factors of symptomatic knee OA. Here cartilage loss using 3 Tesla (3 T) MRI is analysed over 1 year in a subset of the OAI, together with its association with various risk factors. Methods An age- and gender-stratified subsample of the OAI progression subcohort (79 women and 77 men, mean (SD) age 60.9 (9.9) years, body mass index (BMI) 30.3 (4.7)) with both frequent symptoms and radiographic OA in at least one knee was studied. Coronal FLASHwe (fast low angle shot with water excitation) MRIs of the right knee were acquired at 3 T. Seven readers segmented tibial and femoral cartilages blinded to order of acquisition. Segmentations were quality controlled by one expert. Results The reduction in mean cartilage thickness (ThC) was greater (p = 0.004) in the medial than in the lateral compartment, greater (p = 0.001) in the medial femur (−1.9%) than in the medial tibia (−0.5%) and greater (p = 0.011) in the lateral tibia (−0.7%) than in the lateral femur (0.1%). Multifactorial analysis of variance did not reveal significant differences in the rate of change in ThC by sex, BMI, symptoms and radiographic knee OA status. Knees with Kellgren–Lawrence grade 2 or 3 and with a BMI >30 tended to display greater changes. Conclusions In this sample of the OAI progression subcohort, the greatest, but overall very modest, rate of cartilage loss was observed in the weight-bearing medial femoral condyle. Knees with radiographic OA in obese participants showed trends towards higher rates of change than those of other participants, but these trends did not reach statistical significance. PMID:18519425

  4. The effect of monthly 50,000 IU or 100,000 IU vitamin D supplements on vitamin D status in premenopausal Middle Eastern women living in Auckland.

    Science.gov (United States)

    Mazahery, H; Stonehouse, W; von Hurst, P R

    2015-03-01

    Middle Eastern female immigrants are at an increased risk of vitamin D deficiency and their response to prescribed vitamin D dosages may not be adequate and affected by other factors. The objectives were to determine vitamin D deficiency and its determinants in Middle Eastern women living in Auckland, New Zealand (Part-I), and to determine serum 25-hydroxyvitamin D (serum-25(OH)D) response to two prescribed vitamin D dosages (Part-II) in this population. Women aged ⩾20 (n=43) participated in a cross-sectional pilot study during winter (Part-I). In Part-II, women aged 20-50 years (n=62) participated in a randomised, double-blind placebo-controlled trial consuming monthly either 50,000, 100,000 IU vitamin D3 or placebo for 6 months (winter to summer). All women in Part-I and 60% women in Part-II had serum-25(OH)D<50 nmol/l. Serum-25(OH)D was higher in prescribed vitamin D users than nonusers (P=0.001) and in Iranians than Arab women (P=0.001; Part-I). Mean (s.d.) serum-25(OH)D increased in all groups (time effect, P<0.001) and differed between groups (time × dosage interaction, P<0.001; 50,000 IU: from 44.0±16.0 to 70.0±15.0 nmol/l; 100,000 IU: 48.0±11.0 to 82.0±17.0 nmol/l; placebo: 45.0±18.0 to 54.0±18.0 nmol/l). Only 32% and 67% achieved serum-25(OH)D⩾75 nmol/l with 50,000 and 100,000 IU/month, respectively. Predictors of 6-month change in serum-25(OH)D were dose (B-coefficient±s.e.; 14.1±2.4, P<0.001), baseline serum-25(OH)D (-0.6±0.1, P<0.001) and body fat percentage (-0.7±0.3, P=0.01). Vitamin D deficiency/insufficiency is highly prevalent in this population. Monthly 100,000 IU vitamin D for 6 months is more effective than 50,000 IU in achieving serum-25(OH)D ⩾75 nmol/l; however, a third of women still did not achieve these levels.

  5. Levels of myosin heavy chain mRNA transcripts and content of protein isoforms in the slow soleus muscle of 7 month-old rats with altered thyroid status

    Czech Academy of Sciences Publication Activity Database

    Vadászová, Adriana; Hudecová, S.; Križanová, O.; Soukup, Tomáš

    2006-01-01

    Roč. 55, č. 2 (2006), s. 221-225 ISSN 0862-8408 R&D Projects: GA ČR(CZ) GD305/03/H148; GA ČR(CZ) GA304/05/0327 Grant - others:VEGA(SK) 2/6078; SAV(SK) APVT-51-027404; NATO(XE) 979876; MYORES(XE) 511978 Institutional research plan: CEZ:AV0Z50110509 Keywords : myosin heavy chain * thyroid hormones status * mRNA transcripts Subject RIV: ED - Physiology Impact factor: 2.093, year: 2006

  6. Natural gas monthly

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1998-01-01

    The Natural Gas Monthly highlights activities, events, and analyses of interest to public and private sector organizations associated with the natural gas industry. Volume and price data are presented each month for natural gas production, distribution, consumption, and interstate pipeline activities. Producer-related activities and underground storage data are also reported. From time to time, the Natural Gas Monthly features articles designed to assist readers in using and interpreting natural gas information.

  7. Deadline Compliance Status Reports

    Data.gov (United States)

    Department of Housing and Urban Development — These monthly Deadline Compliance Status Reports assist Participating Jurisdictions and HUD Field Offices in monitoring compliance with the 2-year commitment and...

  8. An Assessment of the Food and Nutrition Security Status of Weaned 7-12 Months Old Children in Rural and Peri-Urban Communities of Gauteng and Limpopo Provinces, South Africa.

    Science.gov (United States)

    Ntila, Sithandiwe; Siwela, Muthulisi; Kolanisi, Unathi; Abdelgadir, Hafiz; Ndhlala, Ashwell

    2017-09-01

    This study assessed the food and nutrition security status of children receiving complementary food in rural and peri-urban communities. A group of 106 mothers from Lebowakgomo village and Hammanskraal Township, respectively, participated in the survey. Additionally, six focus group discussions were conducted per study area to assess the mothers' perceptions about children's food access. The Children's Food Insecurity Access Scale (CFIAS) was used to assess the food security status (access) of the children. The Individual Dietary Diversity Score (IDDS) together with the unquantified food consumption frequency survey were used as a proxy measure of the nutritional quality of the children's diets. The age and weight of the children obtained from the children's clinic health cards were used to calculate Weight-for-Age Z scores (WAZ) in order to determine the prevalence of underweight children. The findings showed that a large percentage of children were severely food-insecure, 87% and 78%, in rural and peri-urban areas, respectively. Additionally, Lebowakgomo children (23.6%) and Hammanskraal children (17.9%) were severely underweight. Overall, children's diets in both study areas was characterized by nutrient-deficient complementary foods. Cheaper foods with a longer stomach-filling effect such as white maize meal and sugar were the most commonly purchased and used. Hence, the children consumed very limited amounts of foods rich in proteins, minerals, and vitamins, which significantly increased the risk of their being malnourished.

  9. Progress report 1979

    International Nuclear Information System (INIS)

    1980-12-01

    This progress report deals with technical and research work done at the AAEC Research Establishment in the twelve month period ending September 30, 1979. Work done in the following research divisions is reported: Applied Maths and Computing, Chemical Technology, Engineering Research, Environmental Science, Instrumentation and Control, Isotope, Materials and Physics

  10. Progress report 1979

    International Nuclear Information System (INIS)

    1980-12-01

    This progress report deals with service oriented work performed at the AAEC Research Establishment in the twelve month period ending September 30, 1979. Services provided by the Engineering Services Division, the Safety Department, Site Information Services Department and Commercial Applications are described

  11. Evolution of Serum 25OHD in Response to Vitamin D3-Fortified Yogurts Consumed by Healthy Menopausal Women: A 6-Month Randomized Controlled Trial Assessing the Interactions between Doses, Baseline Vitamin D Status, and Seasonality.

    Science.gov (United States)

    Bonjour, Jean-Philippe; Dontot-Payen, Flore; Rouy, Emilien; Walrand, Stephane; Rousseau, Brigitte

    2018-01-01

    Adequate vitamin D status contributes to bone fragility risk reduction and possibly other pathological conditions that occur with aging. In response to pharmaceutical vitamin D 3 supplements, several studies have documented the influence of doses, baseline status, and seasonality on serum 25-hydroyvitamin D (s25OHD). Using fortified yogurt, we investigated in one randomized controlled trial how both baseline status, as assessed by measuring s25OHD prior the onset of the trial, and the season of enrollment quantitatively influenced the response to the supplemented (Suppl.) of vitamin D 3 (VitD 3 ) in healthy community-dwelling women. A 24-week controlled trial was conducted in menopausal women (mean age: 61.5). Participants were randomized into 3 groups (Gr): Gr.Suppl.0, time controls maintaining dietary habits; Gr.Suppl.5 and Gr.Suppl.10 consuming one and two 125-g servings of VitD 3 -fortified yogurts with 5- and 10-µg daily doses, respectively. The 16 intervention weeks lasted from early January to mid-August, the 8 follow-up weeks, without product, from late August to mid-October. Before enrollment, subjects were randomized into 2 s25OHD strata: low stratum (LoStr): 25-50 nmol/L; high stratum (HiStr): >50-75 nmol/L. All enrolled participants adhered to the protocol throughout the 24-week study: Gr.Suppl.0 (n = 45), Gr.Suppl.5 (n = 44), and Gr.Suppl.10 (n = 44). Over the 16 intervention and 8 follow-up weeks, s25OHD increased in both supplemented groups, more in Gr.Suppl.10 than in Gr.Suppl.5. At the end of the intervention, the subject proportion with s25OHD ≥ 50 nmol/L was 37.8, 54.5, and 63.6% in Gr.Suppl.0, Gr.Suppl.5, and Gr.Suppl.10, respectively. The constant rate of s25OHD per supplemental VitD 3 microgram was greater in LoStr than HiStr. The s25OHD increase was greater with late (mid-March) than early (mid-January) inclusion. This randomized trial demonstrates (1) a dose-dependent s25OHD improvement related to fortified yogurt consumption; (2) an

  12. Evolution of Serum 25OHD in Response to Vitamin D3–Fortified Yogurts Consumed by Healthy Menopausal Women: A 6-Month Randomized Controlled Trial Assessing the Interactions between Doses, Baseline Vitamin D Status, and Seasonality

    Science.gov (United States)

    Bonjour, Jean-Philippe; Dontot-Payen, Flore; Rouy, Emilien; Walrand, Stephane; Rousseau, Brigitte

    2018-01-01

    ABSTRACT Background: Adequate vitamin D status contributes to bone fragility risk reduction and possibly other pathological conditions that occur with aging. In response to pharmaceutical vitamin D3 supplements, several studies have documented the influence of doses, baseline status, and seasonality on serum 25-hydroyvitamin D (s25OHD). Objective: Using fortified yogurt, we investigated in one randomized controlled trial how both baseline status, as assessed by measuring s25OHD prior the onset of the trial, and the season of enrollment quantitatively influenced the response to the supplemented (Suppl.) of vitamin D3 (VitD3) in healthy community-dwelling women. Methods: A 24-week controlled trial was conducted in menopausal women (mean age: 61.5). Participants were randomized into 3 groups (Gr): Gr.Suppl.0, time controls maintaining dietary habits; Gr.Suppl.5 and Gr.Suppl.10 consuming one and two 125-g servings of VitD3-fortified yogurts with 5- and 10-µg daily doses, respectively. The 16 intervention weeks lasted from early January to mid-August, the 8 follow-up weeks, without product, from late August to mid-October. Before enrollment, subjects were randomized into 2 s25OHD strata: low stratum (LoStr): 25–50 nmol/L; high stratum (HiStr): >50–75 nmol/L. Results: All enrolled participants adhered to the protocol throughout the 24-week study: Gr.Suppl.0 (n = 45), Gr.Suppl.5 (n = 44), and Gr.Suppl.10 (n = 44). Over the 16 intervention and 8 follow-up weeks, s25OHD increased in both supplemented groups, more in Gr.Suppl.10 than in Gr.Suppl.5. At the end of the intervention, the subject proportion with s25OHD ≥ 50 nmol/L was 37.8, 54.5, and 63.6% in Gr.Suppl.0, Gr.Suppl.5, and Gr.Suppl.10, respectively. The constant rate of s25OHD per supplemental VitD3 microgram was greater in LoStr than HiStr. The s25OHD increase was greater with late (mid-March) than early (mid-January) inclusion. Conclusion: This randomized trial demonstrates (1) a dose-dependent s25OHD

  13. Six months into Myanmar's minimum wage: Reflecting on progress ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    2016-04-25

    Apr 25, 2016 ... Participants examined recent results from an IDRC-funded enterprise survey, ... of a minimum wage, and how they have coped with the new situation.” ... Debate on the impact of minimum wages on employment continues ...

  14. December 2013 pulmonary case of the month: natural progression

    Directory of Open Access Journals (Sweden)

    Viggiano RW

    2013-12-01

    Full Text Available No abstract available. Article truncated at 150 words. History of Present Illness A 68 year old woman was seen for increased back pain in April 2012. In 2000 she had a right lower lobe lung resection for low grade adenocarcinoma, bronchoalveolar type, nonmucinous. Her mass was 2.6 cm in maximal dimension extending to but not invading the pleura. There were clear surgical margins but involvement of one bronchial node. Multiple mediastinal nodes were negative. She had back pain for many years and yearly CTs were negative for metastatic disease. PMH, SH, FH Other than the above there was no significant past medical history, social history or family history. Medications Non-steroidal anti-inflammatory drugs for pain Nitrofurantoin for chronic urinary tract infections Physical Examination There was tenderness to palpation over the mid-thoracic spine and evidence of a previous thoracotomy. Laboratory Her complete blood count (CBC, urinanalysis, liver function tests, and calcium were all within normal limits. Radiology An x-ray of …

  15. 48 CFR 1552.211-72 - Monthly progress report.

    Science.gov (United States)

    2010-10-01

    ..., display the expended direct labor hours and costs broken out by EPA contract labor hour category for the... cumulative contract life display: the negotiated, expended and remaining direct labor hours and costs broken... consultant. (iv) Display the estimated direct labor hours and costs to be expended during the next reporting...

  16. TARP Monthly Housing Scorecard

    Data.gov (United States)

    Department of the Treasury — Treasury and the U.S. Department of Housing and Urban Development (HUD) jointly produce a Monthly Housing Scorecard on the health of the nation’s housing market. The...

  17. Molecule of the Month

    Indian Academy of Sciences (India)

    Molecule of the Month - Adamantane - A Plastic Piece of Diamond. J Chandrasekhar. Volume 16 Issue 12 ... Keywords. Adamantane; diamondoid systems; plastic crystals. ... Resonance – Journal of Science Education | News. © 2017 Indian ...

  18. Oceanographic Monthly Summary

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Oceanographic Monthly Summary contains sea surface temperature (SST) analyses on both regional and ocean basin scales for the Atlantic, Pacific, and Indian Oceans....

  19. 76 FR 68617 - National Diabetes Month, 2011

    Science.gov (United States)

    2011-11-04

    ... throughout the year, let us continue to pursue a diabetes-free future for our children, our families, and all... National Diabetes Month, 2011 By the President of the United States of America A Proclamation Though we have made substantial progress in combating diabetes, the number of Americans burdened by this disease...

  20. ISABELLE: a progress report

    Energy Technology Data Exchange (ETDEWEB)

    Hahn, H

    1980-01-01

    This paper discusses the ISABELLE project, which has the objective of constructing a high-energy proton colliding beam facility at Brookhaven National Laboratory. The major technical features of the intersecting storage accelerators with their projected performance are described. Application of over 1000 superconducting magnets in the two rings represents the salient characteristic of the machine. The status of the entire project, the technical progress made so far, and difficulties encountered are reviewed.

  1. ISABELLE: a progress report

    International Nuclear Information System (INIS)

    Hahn, H.

    1980-01-01

    This paper discusses the ISABELLE project, which has the objective of constructing a high-energy proton colliding beam facility at Brookhaven National Laboratory. The major technical features of the intersecting storage accelerators with their projected performance are described. Application of over 1000 superconducting magnets in the two rings represents the salient characteristic of the machine. The status of the entire project, the technical progress made so far, and difficulties encountered are reviewed

  2. Clean Energy Progress Report

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2011-07-01

    For the past several years, the IEA and others have been calling for a clean energy revolution to achieve global energy security, economic growth and climate change goals. This report analyses for the first time progress in global clean energy technology deployment against the pathways that are needed to achieve these goals. It provides an overview of technology deployment status, key policy developments and public spending on RDD&D of clean energy technologies.

  3. Progress Report

    DEFF Research Database (Denmark)

    Duer, Karsten

    1999-01-01

    Progress report describing the work carried out by the Danish participant in the ALTSET project in the period January 1999 to July 1999.......Progress report describing the work carried out by the Danish participant in the ALTSET project in the period January 1999 to July 1999....

  4. Progress Report

    Science.gov (United States)

    2018-05-16

    This report summarizes the annual progress of EPA’s Clean Air Markets Programs such as the Acid Rain Program (ARP) and the Cross-State Air Pollution Rule (CSAPR). EPA systematically collects data on emissions, compliance, and environmental effects, these data are highlighted in our Progress Reports.

  5. Status of progress in IFR development

    International Nuclear Information System (INIS)

    Chang, Y.I.

    1994-01-01

    The author touches on a number of the issues being addressed in work on the IFR reactor concept development at this time. This technology offers the opportunity to achieve a much more efficient utilization of uranium resources in the process of energy generation. Liquid metal coolant is likely to be a design feature of this type reactor, in part due to the passive safety of this design. Fuel reprocessing, and waste management issues are discussed. This reactor design has the advantage of being much better positioned to minimize concerns about nuclear proliferation issues

  6. The Impact of Smoking Status on the Efficacy of Erlotinib in Patients with Advanced Non-small Cell Lung Cancer

    Directory of Open Access Journals (Sweden)

    Yilong WU

    2009-12-01

    Full Text Available Background and objective Erlotinib is a targeted treatment for advanced non-small cell lung cancer. Smoking status may be one of influencing factors of the efficacy of erlotinib. The aim of this study is to explore the impact of smoking status on the efficacy of erlotinib in patients with advanced non-small cell lung cancer. Methods Patients with nonsmall cell lung cancer who had been previously treated with at least one course of platinum based chemotherapy received 150 mg oral doses of erlotinib once daily until disease progression. Response rate, progression-free survival, overall survival were analyzed in the different smoking status groups. Kaplan-Meier method was used to analyze the survival rate. Results Fortyeight patients were enrolled into the study from December 2005 to September 2006. We followed up these patients until 28th December, 2008. Median follow up time was 30 months. The compliance rate was 100%. The response rate was 32.1% in the smoking group and 35% in the never smoking group (P=0.836; The median progression-free survival was 3 months and 9 months, respectively (P=0.033. The median overall survival was 5 months and 17 months, respectively (P=0.162. Conclusion Erlotinib is an effective drug for advanced non-small cell lung cancer patients with different smoking status. Progressionfree survival is better in the never smoking patients than the smoking patients.

  7. Development of complementary feeding recommendations for 12-23-month-old children from low and middle socio-economic status in West Java, Indonesia: contribution of fortified foods towards meeting the nutrient requirement.

    Science.gov (United States)

    Fahmida, Umi; Santika, Otte

    2016-07-01

    Inadequate nutrient intake as part of a complementary feeding diet is attributable to poor feeding practices and poor access to nutritious foods. Household socio-economic situation (SES) has an influence on food expenditure and access to locally available, nutrient-dense foods and fortified foods. This study aimed to develop and compare complementary feeding recommendations (CFR) for 12-23-month-old children in different SES and evaluate the contribution of fortified foods in meeting nutrient requirements. A cross-sectional survey was conducted in low and medium SES households (n 114/group) in urban Bandung district, West Java province, Indonesia. Food pattern, portion size and affordability were assessed, and CFR were developed for the low SES (LSES) and middle SES (MSES) using a linear programming (LP) approach; two models - with and without fortified foods - were run using LP, and the contribution of fortified foods in the final CFR was identified. Milk products, fortified biscuits and manufactured infant cereals were the most locally available and consumed fortified foods in the market. With the inclusion of fortified foods, problem nutrients were thiamin in LSES and folate and thiamin in MSES groups. Without fortified foods, more problem nutrients were identified in LSES, that is, Ca, Fe, Zn, niacin and thiamin. As MSES consumed more fortified foods, removing fortified foods was not possible, because most of the micronutrient-dense foods were removed from their food basket. There were comparable nutrient adequacy and problem nutrients between LSES and MSES when fortified foods were included. Exclusion of fortified foods in LSES was associated with more problem nutrients in the complementary feeding diet.

  8. 24-month fuel cycles

    International Nuclear Information System (INIS)

    Rosenstein, R.G.; Sipes, D.E.; Beall, R.H.; Donovan, E.J.

    1986-01-01

    Twenty-four month reload cycles can potentially lessen total power generation costs. While 24-month cores increase purchased fuel costs, the longer cycles reduce the number of refueling outages and thus enhance plant availability; men-rem exposure to site personnel and other costs associated with reload core design and licensing are also reduced. At dual unit sites an operational advantage can be realized by refueling each plant alternately on a 1-year offset basis. This results in a single outage per site per year which can be scheduled for off-peak periods or when replacement power costs are low

  9. The influence of experimental infection of gilts with swine H1N2 influenza A virus during the second month of gestation on the course of pregnancy, reproduction parameters and clinical status.

    Science.gov (United States)

    Kwit, Krzysztof; Pomorska-Mól, Małgorzata; Markowska-Daniel, Iwona

    2014-06-04

    The course of swine influenza in pigs is reported to be similar to human influenza. Occasionally abortions and other reproduction disorders have been associated with influenza A virus (IAV) infection in pigs. Abortions may be a consequence of high fever, pro-inflammatory cytokines or transplacental transmission of the virus.The role of IAV in the complications observed during pregnancy has been scanty and the true importance of this agent as a cause of reproductive problems in swine is not known. The aim was to determine the possible involvement of swine H1N2 IAV strain on reproductive disorders in pregnant gilts under experimental conditions. The gestation length was from 113 to 116 days, no abortion or any other reproduction disorders were noted. A PCR assay confirms the presence of IAV in the nasal swabs taken from inoculated gilts between 1 and 5 dpi. In the nasal swabs from control gilts and newborn piglets, no IAV genetic material was found. No viral RNA was detected in samples of blood taken from gilts and piglets, placentas, lungs and tracheas taken from piglets euthanized after delivery. The significant decrease in the number and percentage of lymphocytes without leukopenia was observed at 4 dpi in inoculated gilts. The percentage of granulocytes increased significantly at 4 dpi in inoculated pigs. The concentration of IL-6, IL-10 and TNF-α were higher in inoculated gilts, while IL-4 and IFN-γ were not detected in the serum of any of animals. The serum concentrations of C-reactive protein remained stable during study, while haptoglobin concentrations increased significantly after inoculation. The results of the study indicate that infection of pregnant gilts with swine H1N2 IAV in the second month of pregnancy does not cause abortion and other reproduction disorders. No evidence for transplacental transmission of swine H1N2 IAV was found. However, due to subclinical course of influenza in the present experiment caution should be taken in extrapolating

  10. Effect of socioeconomic disadvantage, remoteness and Indigenous status on hospital usage for Western Australian preterm infants under 12 months of age: a population-based data linkage study.

    Science.gov (United States)

    Strobel, Natalie A; Peter, Sue; McAuley, Kimberley E; McAullay, Daniel R; Marriott, Rhonda; Edmond, Karen M

    2017-01-18

    Our primary objective was to determine the incidence of hospital admission and emergency department presentation in Indigenous and non-Indigenous preterm infants aged postdischarge from birth admission to 11 months in Western Australia. Secondary objectives were to assess incidence in the poorest infants from remote areas and to determine the primary causes of hospital usage in preterm infants. Prospective population-based linked data set. All preterm babies born in Western Australia during 2010 and 2011. All-cause hospitalisations and emergency department presentations. There were 6.9% (4211/61 254) preterm infants, 13.1% (433/3311) Indigenous preterm infants and 6.5% (3778/57 943) non-Indigenous preterm infants born in Western Australia. Indigenous preterm infants had a higher incidence of hospital admission (adjusted incident rate ratio (aIRR) 1.24, 95% CI 1.08 to 1.42) and emergency department presentation (aIRR 1.71, 95% CI 1.44 to 2.02) compared with non-Indigenous preterm infants. The most disadvantaged preterm infants (7.8/1000 person days) had a greater incidence of emergency presentation compared with the most advantaged infants (3.1/1000 person days) (aIRR 1.61, 95% CI 1.30 to 2.00). The most remote preterm infants (7.8/1000 person days) had a greater incidence of emergency presentation compared with the least remote preterm infants (3.0/1000 person days; aIRR 1.82, 95% CI 1.49 to 2.22). In Western Australia, preterm infants have high hospital usage in their first year of life. Infants living in disadvantaged areas, remote area infants and Indigenous infants are at increased risk. Our data highlight the need for improved postdischarge care for preterm infants. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/.

  11. Petroleum supply monthly, April 1990

    Energy Technology Data Exchange (ETDEWEB)

    None

    1990-06-26

    The Petroleum Supply Monthly (PSM) is one of a family of three publications produced by the Petroleum Supply Division within the Energy Information Administration (EIA) reflecting different levels of data timeliness and completeness. The other two publications are the Weekly Petroleum Status Report (WPSR) and the Petroleum Supply Annual (PSA). Data presented in the Petroleum Supply Monthly describe (PSM) the supply and disposition of petroleum products in the United States and major US geographic regions. The data series describe production, imports and exports, inter-Petroleum Administration for Defense (PAD) District movements, and inventories by the primary suppliers of petroleum products in the United States (50 States and the District of Columbia). The reporting universe includes those petroleum sectors in Primary Supply.'' Included are: petroleum refiners, motor gasoline blenders, operators of natural gas processing plants and fractionators, inter-PAD transporters, importers, and major inventory holders of petroleum products and crude oil. When aggregated, the data reported by these sectors approximately represent the consumption of petroleum products in the United States. Data presented in the PSM are divided into two sections: (1) the Summary Statistics and (2) the Detailed Statistics.

  12. Molecule of the Month

    Indian Academy of Sciences (India)

    Home; Journals; Resonance – Journal of Science Education; Volume 1; Issue 2. Molecule of the Month Isomers of Benzene - Still Pursuing Dreams. J Chandrasekhar. Feature Article Volume 1 Issue 2 February 1996 pp 80-83. Fulltext. Click here to view fulltext PDF. Permanent link:

  13. Molecule of the Month

    Indian Academy of Sciences (India)

    Home; Journals; Resonance – Journal of Science Education; Volume 16; Issue 12. Molecule of the Month - A Stable Dibismuthene - A Compound with a Bi-Bi Double Bond. V Chandrasekhar. Volume 16 ... Author Affiliations. V Chandrasekhar1. Department of Chemistry, Indian Institute of Technology, Kanpur 208 016, India.

  14. Monthly energy review

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1997-12-01

    This document presents an overview of the Energy Information Administration`s (EIA) recent monthly energy statistics. The statistics cover the major activities of U.S. production, consumption, trade, stocks, and prices for petroleum, natural gas, coal, electricity, and nuclear energy. Also included are international energy and thermal and metric conversion factors.

  15. Photos of the month

    CERN Multimedia

    Claudia Marcelloni de Oliveira

    Congratulations to Adele Rimoldi, ATLAS physicist from Pavia, who ran her first marathon in New York last month. Adele completed the 42.2 km in a time of 4:49:19. She sure makes it look easy!!! The ATLAS pixel service quarter panel in SR1

  16. Molecule of the Month

    Indian Academy of Sciences (India)

    Home; Journals; Resonance – Journal of Science Education; Volume 2; Issue 5. Molecule of the Month Molecular–Chameleon: Solvatochromism at its Iridescent Best! Photon Rao. Feature Article Volume 2 Issue 5 May 1997 pp 69-72. Fulltext. Click here to view fulltext PDF. Permanent link:

  17. Progressive Business

    DEFF Research Database (Denmark)

    Christiansen, Christian O.

    2016-01-01

    Guest Post to the Society for U.S. Intellectual History Blog. Brief introduction to the book Progressive Business: An Intellectual History of the Role of Business in American Society, Oxford U.P., 2015.......Guest Post to the Society for U.S. Intellectual History Blog. Brief introduction to the book Progressive Business: An Intellectual History of the Role of Business in American Society, Oxford U.P., 2015....

  18. 20 CFR 411.180 - What is timely progress toward self-supporting employment?

    Science.gov (United States)

    2010-04-01

    ... Who Are Using a Ticket Introduction § 411.180 What is timely progress toward self-supporting... the previous 12-month progress certification period. In computing any 12-month progress certification...

  19. Chronic progressive multiple sclerosis

    International Nuclear Information System (INIS)

    Buffoli, A.; Micheletti, E.; Capra, R.; Mattioli, F.; Marciano', N.

    1991-01-01

    A long-lasting immunological suppression action seems to be produced by total lymphoid irradiation; some authors emphasize the favorable effect of this treatment on chronic progressive multiple sclerosis. In order to evaluate the actual role of TLI, 6 patients affected with chronic progressive multiple sclerosis were submitted to TLI with shaped and personalized fields at the Istituto del Radio, University of Brescia, Italy. The total dose delivered was 19.8 Gy in 4 weeks, 1.8 Gy/day, 5d/w; a week elapsed between the first and the second irradiation course. Disability according to Kurtzke scale was evaluated, together with blood lymphocyte count and irradiation side-effects, over a mean follow-up period of 20.8 months (range: 13-24). Our findings indicate that: a) disease progression was not markedly reduced by TLI; b) steroid hormones responsivity was restored after irradiation, and c) side-effects were mild and tolerable

  20. Electric power monthly

    Energy Technology Data Exchange (ETDEWEB)

    Smith, Sandra R.; Johnson, Melvin; McClevey, Kenneth; Calopedis, Stephen; Bolden, Deborah

    1992-05-01

    The Electric Power Monthly is prepared by the Survey Management Division; Office of Coal, Nuclear, Electric and Alternate Fuels, Energy Information Administration (EIA), Department of Energy. This publication provides monthly statistics at the national, Census division, and State levels for net generation, fuel consumption, fuel stocks, quantity and quality of fuel, cost of fuel, electricity sales, revenue, and average revenue per kilowatthour of electricity sold. Data on net generation, fuel consumption, fuel stocks, quantity and cost of fuel are also displayed for the North American Electric Reliability Council (NERC) regions. Additionally, statistics by company and plant are published in the EPM on capability of new plants, new generation, fuel consumption, fuel stocks, quantity and quality of fuel, and cost of fuel.

  1. Petroleum marketing monthly

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1995-08-01

    The Petroleum Marketing Monthly (PMM) provides information and statistical data on a variety of crude oils and refined petroleum products. The publication presents statistics on crude oil costs and refined petroleum products sales for use by industry, government, private sector analysts, educational institutions, and consumers. Data on crude oil include the domestic first purchase price, the f.o.b. and landed cost of imported crude oil, and the refiners` acquisition cost of crude oil. Refined petroleum product sales data include motor gasoline, distillates, residuals, aviation fuels, kerosene, and propane. The Petroleum Marketing Division, Office of Oil and Gas, Energy Information Administration ensures the accuracy, quality, and confidentiality of the published data in the Petroleum Marketing Monthly.

  2. Petroleum marketing monthly

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-07-01

    Petroleum Marketing Monthly (PPM) provides information and statistical data on a variety of crude oils and refined petroleum products. The publication presents statistics on crude oil costs and refined petroleum products sales for use by industry, government, private sector analysts, educational institutions, and consumers. Data on crude oil include the domestic first purchase price, the f.o. b. and landed cost of imported crude oil, and the refiners` acquisition cost of crude oil. Refined petroleum product sales data include motor gasoline, distillates, residuals, aviation fuels, kerosene, and propane. The Petroleum Marketing Division, Office of Oil and Gas, Energy Information Administration ensures the accuracy, quality, and confidentiality of the published data in the Petroleum Marketing Monthly.

  3. Petroleum marketing monthly

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-02-01

    The Petroleum Marketing Monthly (PMM) provides information and statistical data on a variety of crude oils and refined petroleum products. The publication presents statistics on crude oil costs and refined petroleum products sales for use by industry, government, private sector analysts, educational institutions, and consumers. Data on crude oil include the domestic first purchase price, the f.o.b. and landed cost of imported crude oil, and the refiners acquisition cost of crude oil. Refined petroleum product sales data include motor gasoline, distillates, residuals, aviation fuels, kerosene, and propane. The Petroleum Marketing Division, Office of Oil and Gas, Energy Information Administration ensures the accuracy, quality, and confidentiality of the published data in the Petroleum Marketing Monthly.

  4. Electric power monthly

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1995-08-01

    The Energy Information Administration (EIA) prepares the Electric Power Monthly (EPM) for a wide audience including Congress, Federal and State agencies, the electric utility industry, and the general public. This publication provides monthly statistics for net generation, fossil fuel consumption and stocks, quantity and quality of fossil fuels, cost of fossil fuels, electricity sales, revenue, and average revenue per kilowatthour of electricity sold. Data on net generation, fuel consumption, fuel stocks, quantity and cost of fossil fuels are also displayed for the North American Electric Reliability Council (NERC) regions. The EIA publishes statistics in the EPM on net generation by energy source, consumption, stocks, quantity, quality, and cost of fossil fuels; and capability of new generating units by company and plant. The purpose of this publication is to provide energy decisionmakers with accurate and timely information that may be used in forming various perspectives on electric issues that lie ahead.

  5. Medical Surveillance Monthly Report

    Science.gov (United States)

    2016-12-01

    Illness Prevention and Sun Safety. “Sun Safety.” https:// phc.amedd.army.mil/ topics /discond/hipss/Pages/ SunSafety.aspx. Accessed on 7 December 2016. 22...febrile illness; however, after its wide- spread introduction into immunologically MSMR Vol. 23 No. 12 December 2016 Page 8 naïve populations, a...October 2016 (data as of 22 November 2016) MSMR’s Invitation to Readers Medical Surveillance Monthly Report (MSMR) invites readers to submit topics for

  6. Experimental status of quantum electrodynamics

    International Nuclear Information System (INIS)

    Drell, S.D.

    1978-10-01

    This review of the experimental status of quantum electrodynamics covers the fine structure constant, the muon g-2 value, the Lamb shift in hydrogen, the finite proton radius, progress in muonium, and positronium. 37 references

  7. Determination of lactic acid level in systemic liquids in children with progressive encephalopathies.

    Science.gov (United States)

    Marszał, Elzbieta; Wojaczyńska-Stanek, Katarzyna; Pietruszewski, Jerzy; Emich-Widera, Ewa; Bielińska-Bujniewicz, Eugenia

    2002-03-01

    This article reports the results of research into the activities of lactic acid concentrations in the body fluids of children with progressive encephalopathies (PE) in comparison to patients with non-progressive encephalopathies (NPE) and those with non-progressive encephalopathies with concomitant epilepsy (NPEE). The study was designed to determine whether there is difference between the serum and CSF lactic acid concentrations in children with progressive encephalopathies (PE), static (non-progressive) encephalopathies (NPE) and non progressive encephalopathies with concomitant epilepsy (NPEE), and whether the clinical status correlates with the concentration of these biochemical markers in children with PE. The assessment involved 138 children of both sexes, whose age ranged between 8 months and 15 years, diagnosed and treated in the Neurology Department at the Pediatric Clinic of the Silesian Medical Academy in Katowice between 1995 and 1997. Lactate concentrations were determined in serum and cerebro-spinal fluid and analyzed statistically. The findings showed higher serum and CSF concentrations in children with PE than in patients who manifested non-progressive forms of encephalopathy. The degree of clinical symptom aggravation in PE children was likewise analyzed and compared to the values of lactate concentrations in body fluids; however, no correlation was found between these parameters. Children with progressive encephalopathies present higher lactate concentrations in serum and cerebrospinal fluid than patients with static (non-progressive) encephalopathy.

  8. Petroleum marketing monthly

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1995-11-01

    The Petroleum Marketing Monthly (PMM) provides information and statistical data on a variety of crude oils and refined petroleum products. The publication presents statistics on crude oil costs and refined petroleum products sales for use by industry, government, private sector analysts, educational institutions, and consumers. Data on crude oil include the domestic first purchase price, the f.o.b. and landed cost of imported crude oil, and the refiners` acquisition cost of crude oil. Refined petroleum product sales data include motor gasoline, distillates, residuals, aviation fuels, kerosene, and propane. The Petroleum Marketing Division, Office of Oil and Gas, Energy Information Administration ensures the accuracy, quality, and confidentiality of the published data.

  9. Benchmarking monthly homogenization algorithms

    Science.gov (United States)

    Venema, V. K. C.; Mestre, O.; Aguilar, E.; Auer, I.; Guijarro, J. A.; Domonkos, P.; Vertacnik, G.; Szentimrey, T.; Stepanek, P.; Zahradnicek, P.; Viarre, J.; Müller-Westermeier, G.; Lakatos, M.; Williams, C. N.; Menne, M.; Lindau, R.; Rasol, D.; Rustemeier, E.; Kolokythas, K.; Marinova, T.; Andresen, L.; Acquaotta, F.; Fratianni, S.; Cheval, S.; Klancar, M.; Brunetti, M.; Gruber, C.; Prohom Duran, M.; Likso, T.; Esteban, P.; Brandsma, T.

    2011-08-01

    The COST (European Cooperation in Science and Technology) Action ES0601: Advances in homogenization methods of climate series: an integrated approach (HOME) has executed a blind intercomparison and validation study for monthly homogenization algorithms. Time series of monthly temperature and precipitation were evaluated because of their importance for climate studies and because they represent two important types of statistics (additive and multiplicative). The algorithms were validated against a realistic benchmark dataset. The benchmark contains real inhomogeneous data as well as simulated data with inserted inhomogeneities. Random break-type inhomogeneities were added to the simulated datasets modeled as a Poisson process with normally distributed breakpoint sizes. To approximate real world conditions, breaks were introduced that occur simultaneously in multiple station series within a simulated network of station data. The simulated time series also contained outliers, missing data periods and local station trends. Further, a stochastic nonlinear global (network-wide) trend was added. Participants provided 25 separate homogenized contributions as part of the blind study as well as 22 additional solutions submitted after the details of the imposed inhomogeneities were revealed. These homogenized datasets were assessed by a number of performance metrics including (i) the centered root mean square error relative to the true homogeneous value at various averaging scales, (ii) the error in linear trend estimates and (iii) traditional contingency skill scores. The metrics were computed both using the individual station series as well as the network average regional series. The performance of the contributions depends significantly on the error metric considered. Contingency scores by themselves are not very informative. Although relative homogenization algorithms typically improve the homogeneity of temperature data, only the best ones improve precipitation data

  10. [Research progress on fascioliasis].

    Science.gov (United States)

    Liu, Qian; Cheng, Na; Zhou, Yan; Xu, Xue-Nian

    2013-06-01

    Fascioliasis is an important zoonosis caused by Fasciola spp. It can cause pathological damages to human liver and gallbladder, as well as economic loss in animal husbandry. Fascioliasis can be easily misdiagnosed with other hepatobiliary diseases. The appearance of resistance to triclabendazole is an issue problem for fascioliasis control. Therefore, research for better diagnostic methods, effective drugs and vaccines become to the focus of fascioliasis control. This article summarizes the progress on epidemiological status, diagnostic method, therapy, drug resistance, vaccine and omics of fascioliasis.

  11. Petroleum supply monthly, January 1996

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-02-15

    The Petroleum Supply Monthly (PSM) is one of a family of four publications produced by the Petroleum Supply Division within the Energy Information Administration (EIA) reflecting different levels of data timeliness and completeness. The other publications are the Weekly Petroleum Status Report (WPSR), the Winter Fuels Report, and the Petroleum Supply Annual (PSA). Data presented in the PSM describe the supply and disposition of petroleum products in the United States and major US geographic regions. The data series describe production, imports and exports, inter-Petroleum Administration for Defense (PAD) District movements, and inventories by the primary suppliers of petroleum products in the United States (50 States and the District of Columbia). The reporting universe includes those petroleum sectors in primary supply. Included are: petroleum refiners, motor gasoline blenders, operators of natural gas processing plants and fractionators, inter-PAD transporters, importers, and major inventory holders of petroleum products and crude oil. When aggregated, the data reported by these sectors approximately represent the consumption of petroleum products in the United States. Data presented in the PSM are divided into two sections: Summary Statistics and Detailed Statistics.

  12. Petroleum supply monthly, October 1993

    Energy Technology Data Exchange (ETDEWEB)

    1993-10-26

    The Petroleum Supply Monthly (PSM) is one of a family of four publications produced by the Petroleum Supply Division within the Energy Information Administration (EIA) reflecting different levels of data timeliness and completeness. The other publications are the Weekly Petroleum Status Report (WPSR), the Winter Fuels Report, and the Petroleum Supply Annual (PSA). Data presented in the PSM describe the supply and disposition of petroleum products in the United States and major US geographic regions. The data series describe production, imports and exports, inter-Petroleum Administration for Defense (PAD) District movements, and inventories by the primary suppliers of petroleum products in the United States (50 States and the District of Columbia). The reporting universe includes those petroleum sectors in primary supply. Included are: petroleum refiners, motor gasoline blenders, operators of natural gas processing plants and fractionators, inter-PAD transporters, importers, and major inventory holders of petroleum products and crude oil. When aggregated, the data reported by these sectors approximately represent the consumption of petroleum products in the United States. Data presented in the PSM are divided into two sections: Summary Statistics and Detailed Statistics.

  13. Petroleum Supply Monthly, August 1990

    Energy Technology Data Exchange (ETDEWEB)

    1990-10-30

    The Petroleum Supply Monthly (PSM) is one of a family of three publications produced by the Petroleum Supply Division within the Energy Information administration (EIA) reflecting different levels of data timeliness and completeness. The other two publications are the Weekly Petroleum Status Report (WPSR) and the Petroleum Supply Annual (PSA). Data presented in the PSM describe the supply and disposition of petroleum products in the United States and major US geographic regions. The data series describe production, imports and exports, inter-Petroleum Administration for Defense (PAD) district movements, and inventories by the primary suppliers of petroleum products in the United States (50 States and the District of Columbia). The reporting universe includes those petroleum sectors in Primary Supply. Included are: petroleum refiners, motor gasoline blenders, operators of natural gas processing plants and fractionators, inter-PAD transporters, importers, and major inventory holders of petroleum products and crude oil. When aggregated, the data reported by these sectors approximately represent the consumption of petroleum products in the United States. Data presented in the PSM are divided into two sections (1) the Summary Statistics and (2) the Detailed Statistics.

  14. Petroleum supply monthly, September 1991

    Energy Technology Data Exchange (ETDEWEB)

    1991-09-30

    The Petroleum Supply Monthly (PSM) is one of a family of three publications produced by the Petroleum Supply Division within the Energy Information Administration (EIA) reflecting different levels of data timeliness and completeness. The other two publications are the Weekly Petroleum Status Report (WPSR) and the Petroleum Supply Annual (PSA). Data presented in PSM describe the supply and disposition of petroleum products in the United States and major US geographic regions. The data series describe production, imports and exports, inter-Petroleum Administrations for Defense (PAD) District movements, and inventories by the primary suppliers of petroleum products in the United States (50 states and the District of Columbia). The reporting universe includes those petroleum sectors in Primary Supply. Included are: petroleum refiners, motor gasoline blenders, operators of natural gas processing plants and fractionators, inter-PAD transporters, importers, and major inventory holders of petroleum products and crude oil. When aggregated, the data reported by these sectors approximately represent the consumption of petroleum products in the United States. Data presented in the PSM are divided into two sections (1) the Summary Statistics and (2) the Detailed Statistics. 65 tabs.

  15. Recent progress in sodium technology

    Energy Technology Data Exchange (ETDEWEB)

    Hallett, W. J.

    1963-10-15

    Progress over the past year in U. S. laboratories studying some of the materials and engineering problems that must be resolved in bringing the technology of sodium to an economically and technically attractive point is reviewed. The status of sodium cooled power reactors in the U. S. is described. (P.C.H.)

  16. Yucca Mountain Project technical status report (TSR), October 1989--March 1990

    International Nuclear Information System (INIS)

    1990-01-01

    This Yucca Mountain Project Technical Status Report (TSR) on site characterization is the second in a series of reports that will be issued at approximately six-month intervals during site characterization. In addition, progress made toward the initiation and conduct of new site characterization activities is included. For this report, information on the technical progress made by Yucca Mountain Project participating organizations has been compiled covering the period from October 1989, through March 31, 1990. The status report consists of three sections: an introductory section; a section on the status of site characterization, which includes preparatory activities, sites programs, repository design, seals system design, waste package design, and performance assessment; and a reference section, which provides a complete listing of all published documents cited in the text. 59 refs

  17. Epidemiological factors in admissions for diarrhoea in 6 - 60-month ...

    African Journals Online (AJOL)

    Objectives. To describe the diarrhoea admissions and the influencing factors in 6 - 60-month-old children at Morogoro Regional Hospital. Design. A retrospective descriptive study of the type of diarrhoea, patient age, home address, nutritional status, diagnosed infection, month of admission, admission duration and outcome ...

  18. Hanford Atomic Products Operation monthly report, February 1954

    Energy Technology Data Exchange (ETDEWEB)

    McCune, F.K.

    1954-03-23

    This is a progress report of the production reactors on the Hanford Reservation for the month of February 1951. This report takes each division (e.g., manufacturing, medical, accounting, occupational safety, security, reactor operations, etc.) of the site and summarizes its accomplishments and employee relations for that month.

  19. Hanford Atomic Products Operation monthly report, April 1953

    Energy Technology Data Exchange (ETDEWEB)

    McCune, F.K.

    1953-05-20

    This is a progress report of the production reactors on the Hanford Reservation for the month of April 1951. This report takes each division (e.g., manufacturing, medical, accounting, occupational safety, security, reactor operations, etc.) of the site and summarizes its accomplishments and employee relations for that month.

  20. Hanford Atomic Products Operation monthly report, January 1954

    Energy Technology Data Exchange (ETDEWEB)

    McCune, F.K.

    1954-02-25

    This is a progress report of the production reactors on the Hanford Reservation for the month of January 1954. This report takes each division (e.g., manufacturing, medical, accounting, occupational safety, security, reactor operations, etc.) of the site and summarizes the accomplishments and employee relations for that month.

  1. Hanford Atomic Products Operation monthly report, March 1953

    Energy Technology Data Exchange (ETDEWEB)

    McCune, F.K.

    1953-04-22

    This is a progress report of the production reactors on the Hanford Reservation for the month of March 1953. This report takes each division (e.g., manufacturing, medical, accounting, occupational safety, security, reactor operations, etc.) of the site and summarizes its accomplishments and employee relations for that month.

  2. Hanford Atomic Products Operation monthly report, April 1954

    Energy Technology Data Exchange (ETDEWEB)

    McCune, F.K.

    1954-05-21

    This is a progress report of the production reactors on the Hanford Reservation for the month of April 1954. This report takes each division (e.g., manufacturing, medical, accounting, occupational safety, security, reactor operations, etc.) of the site and summarizes its accomplishments and employee relations for that month.

  3. Topical report review status

    International Nuclear Information System (INIS)

    1982-08-01

    A Topical Report Review Status is scheduled to be published semi-annually. The primary purpose of this document is to provide periodic progress reports of on-going topical report reviews, to identify those topical reports for which the Nuclear Regulatory Commission (NRC) staff review has been completed and, to the extent practicable, to provide NRC management with sufficient information regarding the conduct of the topical report program to permit taking whatever actions deemed necessary or appropriate. This document is also intended to be a source of information to NRC Licensing Project Managers and other NRC personnel regarding the status of topical reports which may be referenced in applications for which they have responsibility. This status report is published primarily for internal NRC use in managing the topical report program, but is also used by NRC to advise the industry of report review status

  4. Topical report review status

    International Nuclear Information System (INIS)

    1983-01-01

    A Topical Report Review Status is scheduled to be published semi-annually. The primary purpose of this document is to provide periodic progress reports of on-going topical report reviews, to identify those topical reports for which the Nuclear Regulatory Commission (NRC) staff review has been completed and, to the extent practicable, to provide NRC management with sufficient information regarding the conduct of the topical report program to permit taking whatever actions deemed necessary or appropriate. This document is also intended to be a source of information to NRC Licensing Project Managers and other NRC personnel regarding the status of topical reports which may be referenced in applications for which they have responsibility. This status report is published primarily for internal NRC use in managing the topical report program, but is also used by NRC to advise the industry of report review status

  5. Measuring progress

    DEFF Research Database (Denmark)

    Wahlberg, Ayo

    2007-01-01

    In recent years, sociological examinations of genetics, therapeutic cloning, neuroscience and tissue engineering have suggested that 'life itself' is currently being transformed through technique with profound implications for the ways in which we understand and govern ourselves and others...... in much the same way that mortality rates, life expectancy or morbidity rates can. By analysing the concrete ways in which human progress has been globally measured and taxonomised in the past two centuries or so, I will show how global stratifications of countries according to their states...

  6. ARGUS progress report 1982

    International Nuclear Information System (INIS)

    Darden, C.W. III.

    1982-01-01

    On September 7th, 1982, following four years of planning and construction, the magnetic solenoid detector ARGUS was moved into one of the two interaction regions of the electron-positron storage ring DORIS. A month later the ring started delivering luminosity for physics research, specifically, the study of the formation and decay of members of the Upsilon family of mesons. These mesons are bound states, b anti b, of the heaviest of the five known quarks and therefore of considerable interest. This report describes the progress made during the year from March 1982 to March 1983 with emphasis on the experience gained during the first running period

  7. Progressivity Enhanced

    Directory of Open Access Journals (Sweden)

    Marko Hren

    2013-09-01

    Full Text Available Rather than a scientific text, the author contributes a concise memorandum from the originator of the idea who has managed the campaign for the conversion of the military barracks into a creative cluster between 1988 and 2002, when he parted ways with Metelkova due to conflicting views on the center’s future. His views shed light on a distant period of time from a perspective of a participant–observer. The information is abundantly supported by primary sources, also available online. However, some of the presented hypotheses are heavily influenced by his personal experiences of xenophobia, elitism, and predatorial behavior, which were already then discernible on the so-called alternative scene as well – so much so that they obstructed the implementation of progressive programs. The author claims that, in spite of the substantially different reality today, the myths and prejudices concerning Metelkova must be done away with in order to enhance its progressive nature. Above all, the paper calls for an objective view on internal antagonisms, mainly originating in deep class divisions between the users. These make a clear distinction between truly marginal ndividuals and the overambitious beau-bourgeois, as the author labels the large part of users of Metelkova of »his« time. On these grounds, he argues for a robust approach to ban all forms of xenophobia and self-ghettoization.

  8. SuperB Progress Report: Detector

    International Nuclear Information System (INIS)

    Grauges, E.; Donvito, G.; Spinoso, V.; Manghisoni, M.; Re, V.; Traversi, G.; Eigen, G.; Fehlker, D.; Helleve, L.; Cheng, C.; Chivukula, A.; Doll, D.; Echenard, B.; Hitlin, D.; Ongmongkolkul, P.; Porter, F.; Rakitin, A.; Thomas, M.; Zhu, R.; Tatishvili, G.; Andreassen, R.; Fabby, C.; Meadows, B.; Simpson, A.; Sokoloff, M.; Tomko, K.; Fella, A.; Andreotti, M.; Baldini, W.; Calabrese, R.; Carassiti, V.; Cibinetto, G.; Cotta Ramusino, A.; Gianoli, A.; Luppi, E.; Munerato, M.; Santoro, V.; Tomassetti, L.; Stoker, D.; Bezshyyko, O.; Dolinska, G.; Arnaud, N.; Beigbeder, C.; Bogard, F.; Breton, D.; Burmistrov, L.; Charlet, D.; Maalmi, J.; Perez Perez, L.; Puill, V.; Stocchi, A.; Tocut, V.; Wallon, S.; Wormser, G.; Brown, D.

    2012-01-01

    This report describes the present status of the detector design for SuperB. It is one of four separate progress reports that, taken collectively, describe progress made on the SuperB Project since the publication of the SuperB Conceptual Design Report in 2007 and the Proceedings of SuperB Workshop VI in Valencia in 2008.

  9. SuperB Progress Report: Detector

    Energy Technology Data Exchange (ETDEWEB)

    Grauges, E.; /Barcelona U., ECM; Donvito, G.; Spinoso, V.; /INFN, Bari /Bari U.; Manghisoni, M.; Re, V.; Traversi, G.; /INFN, Pavia /Bergamo U., Ingengneria Dept.; Eigen, G.; Fehlker, D.; Helleve, L.; /Bergen U.; Carbone, A.; Di Sipio, R.; Gabrielli, A.; Galli, D.; Giorgi, F.; Marconi, U.; Perazzini, S.; Sbarra, C.; Vagnoni, V.; Valentinetti, S.; Villa, M.; Zoccoli, A.; /INFN, Bologna /Bologna U. /Caltech /Carleton U. /Cincinnati U. /INFN, CNAF /INFN, Ferrara /Ferrara U. /UC, Irvine /Taras Shevchenko U. /Orsay, LAL /LBL, Berkeley /UC, Berkeley /Frascati /INFN, Legnaro /Orsay, IPN /Maryland U. /McGill U. /INFN, Milan /Milan U. /INFN, Naples /Naples U. /Novosibirsk, IYF /INFN, Padua /Padua U. /INFN, Pavia /Pavia U. /INFN, Perugia /Perugia U. /INFN, Perugia /Caltech /INFN, Pisa /Pisa U. /Pisa, Scuola Normale Superiore /PNL, Richland /Queen Mary, U. of London /Rutherford /INFN, Rome /Rome U. /INFN, Rome2 /Rome U.,Tor Vergata /INFN, Rome3 /Rome III U. /SLAC /Tel Aviv U. /INFN, Turin /Turin U. /INFN, Padua /Trento U. /INFN, Trieste /Trieste U. /TRIUMF /British Columbia U. /Montreal U. /Victoria U.

    2012-02-14

    This report describes the present status of the detector design for SuperB. It is one of four separate progress reports that, taken collectively, describe progress made on the SuperB Project since the publication of the SuperB Conceptual Design Report in 2007 and the Proceedings of SuperB Workshop VI in Valencia in 2008.

  10. SuperB Progress Reports Accelerator

    CERN Document Server

    Biagini, Maria Enrica; Boscolo, M; Buonomo, B; Demma, T; Drago, A; Esposito, M; Guiducci, S; Mazzitelli, G; Pellegrino, L; Preger, M A; Raimondi, P; Ricci, R; Rotundo, U; Sanelli, C; Serio, M; Stella, A; Tomassini, S; Zobov, M; Bertsche, K; Brachman, A; Cai, Y; Chao, A; Chesnut, R; Donald, M.H; Field, C; Fisher, A; Kharakh, D; Krasnykh, A; Moffeit, K; Nosochkov, Y; Pivi, M; Seeman, J; Sullivan, M.K; Weathersby, S; Weidemann, A; Weisend, J; Wienands, U; Wittmer, W; Woods, M; Yocky, G; Bogomiagkov, A; Koop, I; Levichev, E; Nikitin, S; Okunev, I; Piminov, P; Sinyatkin, S; Shatilov, D; Vobly, P; Bosi, F; Liuzzo, S; Paoloni, E; Bonis, J; Chehab, R; Le Meur, G; Lepercq, P; Letellier-Cohen, F; Mercier, B; Poirier, F; Prevost, C; Rimbault, C; Touze, F; Variola, A; Bolzon, B; Brunetti, L; Jeremie, A; Baylac, M; Bourrion, O; De Conto, J M; Gomez, Y; Meot, F; Monseu, N; Tourres, D; Vescovi, C; Chanci, A; Napoly, O; Barber, D P; Bettoni, S; Quatraro, D

    2010-01-01

    This report details the present status of the Accelerator design for the SuperB Project. It is one of four separate progress reports that, taken collectively, describe progress made on the SuperB Project since the publication of the SuperB Conceptual Design Report in 2007 and the Proceedings of SuperB Workshop VI in Valencia in 2008.

  11. Undernutrition among Honduran children 12-71 months old

    Directory of Open Access Journals (Sweden)

    Nestel Penelope

    1999-01-01

    Full Text Available In 1996, the Ministry of Health of Honduras conducted a national micronutrient survey that included anthropometric measurements to determine the nutrition status of children 12-71 months old. Among the 1 744 children who participated, 38% of them were stunted, including 14% who were severely stunted; 24% were underweight, of which 4% were severely underweight; and 1% were wasted, of which 0.1% were severely wasted. The country can be divided into three groupings based on the level of stunting and underweight: 1 lowest prevalence: Tegucigalpa, San Pedro Sula, and medium cities; 2 medium prevalence: other urban areas, the rural north, and the rural south; and 3 highest prevalence: the rural west. Using logistic regression analysis, the important determinants of stunting were found to be: mother/caretaker's and father's schooling, source of water, the dominion (geographic location and strata in which the child lived, and the "possession score" for ownership of such items as a radio, television, refrigerator, stereo system, and electric iron. The predictors for underweight were micronutrient status, diarrhea, maternal/caretaker's schooling, type of toilet, and possession score. Historical data indicate that the national prevalence of chronic undernutrition has changed little over the last 10 years despite the number of national food and nutrition plans implemented and the significant improvements in health services. It is possible that these positive interventions have been offset by the slow progress in economic development. Future nutrition interventions should take into account household-level perceived needs and priorities in order to set realistic nutrition targets.

  12. Evaluation of keratoconus progression.

    Science.gov (United States)

    Shajari, Mehdi; Steinwender, Gernot; Herrmann, Kim; Kubiak, Kate Barbara; Pavlovic, Ivana; Plawetzki, Elena; Schmack, Ingo; Kohnen, Thomas

    2018-06-01

    To define variables for the evaluation of keratoconus progression and to determine cut-off values. In this retrospective cohort study (2010-2016), 265 eyes of 165 patients diagnosed with keratoconus underwent two Scheimpflug measurements (Pentacam) that took place 1 year apart ±3 months. Variables used for keratoconus detection were evaluated for progression and a correlation analysis was performed. By logistic regression analysis, a keratoconus progression index (KPI) was defined. Receiver-operating characteristic curve (ROC) analysis was performed and Youden Index calculated to determine cut-off values. Variables used for keratoconus detection showed a weak correlation with each other (eg, correlation r=0.245 between RPImin and Kmax, pKPI). KPI was defined by logistic regression and consisted of a Pachymin coefficient of -0.78 (p=0.001), a maximum elevation of back surface coefficient of 0.27 and coefficient of corneal curvature at the zone 3 mm away from the thinnest point on the posterior corneal surface of -12.44 (both pKPI: D-index had a cut-off of 0.4175 (70.6% sensitivity) and Youden Index of 0.606. Cut-off for KPI was -0.78196 (84.7% sensitivity) and a Youden Index of 0.747; both 90% specificity. Keratoconus progression should be defined by evaluating parameters that consider several corneal changes; we suggest D-index and KPI to detect progression. © Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2018. All rights reserved. No commercial use is permitted unless otherwise expressly granted.

  13. Progress report

    International Nuclear Information System (INIS)

    Brumovsky, M.

    1979-01-01

    Progress Report, covering the period up to the end of 1979 year, was sent to the IAEA according to the research agreement No. 1971 /CF. This work covered the following fields: preparation and dummy irradiation experiments with a new experimental capsule of ''CHOUCA-M'' type; measurement of temperature fields and design of specimen holders; measurement of neutron energy spectrum in the irradiation place in our experimental reactor of VVR-S type (Nuclear Research Institute) using a set of activation detectors; unification and calibration of the measurement of neutron fluence with the use of Fe, Cu, Mn-Mg and Co-Al monitors; development and improvement of the measuring apparatus and technique for the dynamic testing of pre-cracked specimens with determination of dynamic parameters of fracture mechanics; preparation and manufacture of testing specimens from the Japanese steels - forging, plate and weld metal; preparation of the irradiation capsule for assembling

  14. Marital status is a prognostic factor in amyotrophic lateral sclerosis.

    Science.gov (United States)

    Spataro, R; Volanti, P; Lo Coco, D; La Bella, V

    2017-12-01

    Several variables have been linked to a shorter survival in patients with amyotrophic lateral sclerosis (ALS), for example, female sex, older age, site of disease onset, rapid disease progression, and a relatively short diagnostic delay. With regard to marital status, previous studies suggested that living with a partner might be associated to a longer survival and a higher likelihood to proceed to tracheostomy. Therefore, to further strengthen this hypothesis, we investigated the role of marital status as a prognostic variable in a cohort of ALS patients. We performed a retrospective analysis on 501 consecutive ALS patients for which a complete disease's natural history and clinical/demographic data were available. At diagnosis, 409 patients (81.6%) were married or lived with a stable partner, whereas 92 patients (18.4%) were single/widowed/divorced. In our ALS cohort, being married was associated with a median longer survival (married, 35 months [24-50] vs unmarried, 27 months [18-42]; Pmarried and unmarried patients were significantly different in many clinical and demographic variables, including age at disease onset, gender, body mass index, and number of children. Cox regression analysis showed that age at onset, diagnostic delay, and marital status were independent predictors of survival. In unmarried patients, female sex was also significantly associated with shorter survival. Marital status is a prognostic factor in ALS, and it significantly affects survival. © 2017 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

  15. Your Baby's Growth: 5 Months

    Science.gov (United States)

    ... Safe Videos for Educators Search English Español Your Baby's Growth: 5 Months KidsHealth / For Parents / Your Baby's ... a cause for concern. How Much Will My Baby Grow? By 5 months, your baby's birth weight ...

  16. Your Child's Development: 9 Months

    Science.gov (United States)

    ... Child's Development: 9 Months Print en español El desarrollo de su hijo: 9 meses Nine-month-olds ... item in each hand at the same time Social and Emotional Development might be fearful of strangers ...

  17. Hanford Works monthly report, October 1952

    Energy Technology Data Exchange (ETDEWEB)

    1952-11-20

    this document presents a summary of work and progress at the Hanford Engineer works for October 1952. The report is divided into sections by department. A plant wide general summary is included at the beginning of the report, after which the departmental summaries begin. The Manufacturing Department reports plant statistics, and summaries for the Metal Preparation, Reactor and Separation sections. The Engineering Department`s section summaries work for the Technical, Design, and Project Sections. Costs for the various departments are presented in the Financial Department`s summary. The Medical, Radiological Sciences, Utilities and General Services, Employee and Public Relations, and Community Real Estate and Services departments have sections presenting their monthly statistics, work, progress, and summaries.

  18. Hanford Works monthly report, February 1953

    Energy Technology Data Exchange (ETDEWEB)

    1953-03-18

    This document presents a summary of work and progress at the Hanford Engineer Works for February 1953. The report is divided into sections by department. A plant wide general summary is included at the beginning of the report, after which the departmental summaries begin. The Manufacturing Department reports plant statistics, and summaries for the Metal Preparation, Reactor and Separation sections. The Engineering Department`s section summaries work for the Technical, Design, and Project Sections. Costs for the various departments are presented in the Financial Department`s summary. The Medical, Radiological Sciences, Utilities and General Services, Employee and Public Relations, and Community Real Estate and Service departments have sections presenting their monthly statistics, work, progress, and summaries.

  19. Hanford Works monthly report, August 1952

    Energy Technology Data Exchange (ETDEWEB)

    1952-09-24

    This document presents a summary of work and progress at the Hanford Engineer Works for August 1952. The report is divided into sections by department. A plant wide general summary is included at the beginning of the report, after which the departmental summaries begin. The Manufacturing Department reports plant statistics, and summaries for the Metal Preparation, Reactor and Separation sections. The Engineering Department` section summaries work for the Technical, Design, and Project Sections. Costs for the various departments are presented in the Financial Department`s summary. The Medical,Radiological Sciences, Utilities and General Services, Employee and Public Relations, and Community Real Estate and Services departments have sections presenting their monthly statistics, work, progress, and summaries.

  20. Hanford Works monthly report, September 1952

    Energy Technology Data Exchange (ETDEWEB)

    1952-10-20

    This document presents a summary of work and progress at the Hanford Engineer Works for September 1952. The report is divided into sections by department. A plant wide general summary is included at the beginning of the report, after which the departmental summaries begin. The Manufacturing Department reports plant statistics, and summaries for the Metal Preparation, Reactor and Separation sections. The Engineering Department`s section summaries work for the Technical Design, and Project Sections. Costs for the various departments are presented in the Financial Department`s summary. The Medical, Radiological Sciences, Utilities and General Services, Employee and Public Relations, and Community Real Estate and Services departments have sections presenting their monthly statistics, work, progress, and summaries.

  1. Hanford Works monthly report, October 1951

    Energy Technology Data Exchange (ETDEWEB)

    1951-11-21

    This document presents a summary of work and progress at the Hanford Engineer Works for October 1951. The report is divided into sections by department. A plant wide general summary is included at the beginning of the report, after which the departmental summaries begin. The Manufacturing Department reports plant statistics, and summaries for the Metal Preparation, Reactor and Separation sections. The Engineering Department`s section summarizes work for the Technical Design, and Project Sections. Costs for the various departments are presented in the Financial Department`s summary. The Medical, Radiological Sciences, Utilities and General Services, Employee and Public Relations, and Community Real Estate and Services departments have sections presenting their monthly statistics, work, progress, and summaries.

  2. Hanford Works monthly report, December 1952

    Energy Technology Data Exchange (ETDEWEB)

    1953-01-23

    This document presents a summary of work and progress at the Hanford Engineer Works for December 1952. The report is divided into sections by department. A plant wide general summary is included at the beginning of the report, after which the departmental summaries begin. The Manufacturing Department reports plant statistics, and summaries for the Metal Preparation, Reactor and Separation sections. The Engineering Department`s section summarizes work for the Technical, Design, and Project Sections. Costs for the various departments are presented in the Financial Department`s summary. The Medical, Radiological Sciences, Utilities and General Services, Employee and Public Relations, and Community Real Estate and Services departments have sections presenting their monthly statistics, work, progress, and summaries.

  3. Monthly energy review, August 1997

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1997-08-01

    The Monthly Energy Review for the month of August 1997, presents an overview of the Energy Information Administration`s recent monthly energy statistics. The statistics cover the major activities of U.S. production, consumption, trade, stocks, and prices for petroleum, natural gas, coal, electricity, and nuclear energy. Also included are international energy and thermal and metric conversion factors.

  4. 48 CFR 2052.211-71 - Technical progress report.

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 6 2010-10-01 2010-10-01 true Technical progress report... Technical progress report. As prescribed at 2011.104-70(b), the contracting officer shall insert the... solicitation. Technical Progress Report (JAN 1993) The contractor shall provide a monthly Technical Progress...

  5. Long-Term Results of Conformal Radiotherapy for Progressive Airway Amyloidosis

    Energy Technology Data Exchange (ETDEWEB)

    Truong, Minh Tam, E-mail: mitruong@bu.edu [Department of Radiation Oncology, Amyloid Treatment and Research Program, Boston University School of Medicine, Boston Medical Center, Boston, MA (United States); Kachnic, Lisa A. [Department of Radiation Oncology, Amyloid Treatment and Research Program, Boston University School of Medicine, Boston Medical Center, Boston, MA (United States); Grillone, Gregory A. [Department of Otolaryngology, Amyloid Treatment and Research Program, Boston University School of Medicine, Boston Medical Center, Boston, MA (United States); Bohrs, Harry K.; Lee, Richard [Department of Radiation Oncology, Amyloid Treatment and Research Program, Boston University School of Medicine, Boston Medical Center, Boston, MA (United States); Sakai, Osamu [Department of Radiology, Amyloid Treatment and Research Program, Boston University School of Medicine, Boston Medical Center, Boston, MA (United States); Berk, John L. [Department of Medicine, Amyloid Treatment and Research Program, Boston University School of Medicine, Boston Medical Center, Boston, MA (United States)

    2012-06-01

    Purpose: To evaluate the efficacy of conformal external beam radiotherapy (RT) for local control of progressive airway amyloidosis. Methods and Materials: We conducted a retrospective review of patients with biopsy-proven progressive airway amyloidosis treated with conformal RT between 2000 and 2006 at Boston Medical Center. The patients were evaluated for performance status and pulmonary function, with computed tomography and endoscopy after RT compared with the pretreatment studies. Local control was defined as the lack of progression of airway wall thickening on computed tomography imaging and stable endobronchial deposits by endoscopy. Results: A total of 10 symptomatic airway amyloidosis patients (3 laryngeal and 7 tracheobronchial) received RT to a median total dose of 20 Gy in 10 fractions within 2 weeks. At a median follow-up of 6.7 years (range, 1.5-10.3), 8 of the 10 patients had local control. The remaining 2 patients underwent repeat RT 6 and 8.4 months after initial RT, 1 for persistent bronchial obstruction and 1 for progression of subglottic amyloid disease with subsequent disease control. The Eastern Cooperative Oncology Group performance status improved at a median of 18 months after RT compared with the baseline values, from a median score of 2 to a median of 1 (p = .035). Airflow (forced expiratory volume in 1 second) measurements increased compared with the baseline values at each follow-up evaluation, reaching a 10.7% increase (p = .087) at the last testing (median duration, 64.8 months). Acute toxicity was limited to Grade 1-2 esophagitis, occurring in 40% of patients. No late toxicity was observed. Conclusions: RT prevented progressive amyloid deposition in 8 of 10 patients, resulting in a marginally increased forced expiratory volume in 1 second, and improved functional capacity, without late morbidity.

  6. Progress report. June to Sept 1975 (1)

    International Nuclear Information System (INIS)

    1975-10-01

    History of the Nuclear Research Centre (NRC) showing objectives and progress during the three month period June to September 1975. Each section is identified within the NRC and its individual activities are defined

  7. Progress on the SNS target station

    International Nuclear Information System (INIS)

    Carne, A.

    1983-01-01

    This review gives progress and modifications covering the last eighteen months, under the five broad areas of target, target assembly, control system, bulk shield and remote handling. Finally a discussion of additional facilities to the SNS is presented

  8. ISIS status report

    International Nuclear Information System (INIS)

    Finney, J.L.; Gray, D.A.

    1989-01-01

    The authors review the progress on ISIS, the pulsed neutron source at the Rutherford-Appleton Laboratory, since the last ICANS meeting. The machine is now running regularly at 100 μA at 750 MeV, and delivering neutrons for an increasing UK and international neutron scattering program. The current status of the operating and development instruments is summarized, and some examples given of recent science. 3 refs., 11 figs., 3 tabs

  9. ATLAS construction status

    International Nuclear Information System (INIS)

    Jenni, P.

    2006-01-01

    The ATLAS detector is being constructed at the LHC, in view of a data-taking startup in 2007. This report concentrates on the progress and the technical challenges of the detector construction, and summarizes the status of the work as of August 2004. The project is on track to allow the highly motivated ATLAS Collaboration to enter into a new exploratory domain of high-energy physics in 2007. (author)

  10. NICMOS status and plans

    Science.gov (United States)

    Thompson, Rodger I.

    1997-01-01

    Near Infrared Camera and Multi-Object Spectrometer (NICMOS) has been in orbit for about 8 months. This is a report on its current status and future plans. Also included are some comments on particular aspects of data analysis concerning dark subtraction, shading, and removal of cosmic rays. At present NICMOS provides excellent images of high scientific content. Most of the observations utilize cameras 1 and 2 which are in excellent focus. Camera 3 is not yet within the range of the focus adjustment mechanism, but its current images are still quite excellent. In this paper we will present the status of various aspects of the NICMOS instrument.

  11. Estado nutricional e carência de ferro em crianças freqüentadoras de creche antes e 15 meses após intervenção nutricional Nutritional status and iron deficiency among children enrolled in a day care center before and after 15 months of nutritional management

    Directory of Open Access Journals (Sweden)

    Terezinha Soares Biscegli

    2008-06-01

    Full Text Available OBJETIVO: Comparar o estado nutricional e a prevalência de carência de ferro em crianças freqüentadoras de creche antes e 15 meses após orientação nutricional e intervenção terapêutica. MÉTODOS: Estudo coorte com 52 crianças de 32 a 78 meses de idade, freqüentadoras de uma creche em Catanduva, São Paulo, avaliadas em dois períodos: antes e 15 meses após receberem tratamento para anemia e correção das alterações no estado nutricional. O estado nutricional das crianças foi avaliado por meio da curva da Organização Mundial de Saúde (2006. O diagnóstico de carência de ferro foi realizado por dosagem de hemoglobina e nível de ferritina sérica. Dados adicionais das crianças não eutróficas foram obtidos por meio de entrevistas com suas mães. RESULTADOS: Observou-se 2% de desnutrição aguda e 8% de obesidade, não havendo diferença significante entre os dois períodos. 12% das crianças apresentaram anemia, havendo diminuição do número de crianças com anemia após o tratamento. Dois novos casos de obesidade e cinco de carência de ferro surgiram durante o período de intervenção nutricional. Das oito crianças com alterações nutricionais no período inicial, 63% das mães procuraram atendimento médico para tratamento. CONCLUSÕES: O tratamento dos distúrbios nutricionais e da carência de ferro diminuiu o número de crianças afetadas. O aparecimento de novos casos de obesidade e anemia serve de alerta para a necessidade de outras medidas preventivas tanto na creche como no âmbito familiar.OBJECTIVE: To compare the nutritional status and the prevalence of iron deficiency among children enrolled in a day care center before and after 15 months of nutritional management. METHODS: Cohort study of 52 children, aged 32 to 78 months, evaluated before and after treatment of anemia and nutritional disturbs in a no-profit day care center in Catanduva, São Paulo, Brazil. The nutritional status was classified according

  12. Three-month outcome of ziv-aflibercept for exudative age-related macular degeneration.

    Science.gov (United States)

    Mansour, Ahmad M; Chhablani, Jay; Antonios, Rafic S; Yogi, Rohit; Younis, Muhammad H; Dakroub, Rola; Chahine, Hasan

    2016-12-01

    In vitro and in vivo studies did not detect toxicity to the retinal pigment epithelium cells using intravitreal ziv-aflibercept. Our purpose is to ascertain the 3-month safety and efficacy in wet age-related macular degeneration (AMD) treated with intravitreal ziv-aflibercept. Prospectively, consecutive patients with wet AMD underwent ziv-aflibercept intravitreal injection (1.25 mg/0.05 mL) from March 2015 to November 2015. Monitoring of best-corrected visual acuity, intraocular inflammation, cataract progression and by spectral domain optical coherence tomography were carried out at baseline day 1, 1 week, 1 month, 2 months and 3 months after injections. 30 eyes were treated (22 Caucasians, 8 Indians; 16 men, 14 women; 14 right eyes and 16 left eyes) with mean age of 74.3 years with 11 treatment-naïve cases and 19 having had treatment-non-naïve. Best-corrected visual acuity improved from baseline logMAR 1.08-0.74 at 1 week, 0.72 at 1 month, 0.67 at 2 months and 0.71 at 3 months (p<0.001 for all time periods). Central macular thickness in microns decreased from 332.8 to 302.0 at 1 week, 244.8 at 1 month, 229.0 at 2 months and 208.2 at 3 months (p<0.001 for all time periods). There were no signs of intraocular inflammation, or change in lens status or increase in intraocular pressure throughout the study. Off label use of ziv-aflibercept improves visual acuity, without detectable ocular toxicity and offers a cheaper alternative to the same molecule aflibercept, especially in low/middle-income countries and in countries where aflibercept (Eylea) is not available. NCT02486484. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/.

  13. Monthly Program Cost Report (MPCR)

    Data.gov (United States)

    Department of Veterans Affairs — The Monthly Program Cost Report (MPCR) replaces the Cost Distribution Report (CDR). The MPCR provides summary information about Veterans Affairs operational costs,...

  14. Monthly energy review, January 1998

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1998-01-01

    This report presents an overview of recent monthly energy statistics. Major activities covered include production, consumption, trade, stocks, and prices for fossil fuels, electricity, and nuclear energy.

  15. Natural gas monthly, August 1995

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1995-08-24

    The Natural Gas Monthly (NGM) highlights activities, events, and analyses of interest to public and private sector organizations associated with the natural gas industry. Volume and price data are presented each month for natural gas production, distribution, consumption, and interstate pipeline activities. Producer-related activities and underground storage data are also reported. From time to time, the NGM features articles designed to assist readers in using and interpreting natural gas information. This month`s feature article is on US Natural Gas Imports and Exports 1994.

  16. Alimentação complementar e estado nutricional de crianças menores de dois anos atendidas no Programa Saúde da Família em Acrelândia, Acre, Amazônia Ocidental Brasileira Complementary feeding and nutritional status of 6-24-month-old children in Acrelândia, Acre State, Western Brazilian Amazon

    Directory of Open Access Journals (Sweden)

    Mariana Tarricone Garcia

    2011-02-01

    Full Text Available Com objetivo de investigar o estado nutricional e alimentação complementar em crianças de 6 a 24 meses, residentes na Amazônia Ocidental Brasileira, um estudo transversal foi realizado na área urbana do Município de Acrelândia, Estado do Acre, com 164 crianças. As prevalências de déficit de estatura/idade e anemia foram de 12% e 40%, respectivamente, e de deficiência de ferro isolada, de 85%. Os níveis séricos das vitaminas A e B12 estavam baixos em 15% e 12% das crianças, respectivamente. Houve baixo consumo alimentar dos seguintes nutrientes (% de crianças abaixo das recomendações: ácido fólico (33%, vitamina C (40%, vitamina A (42%, zinco (46% e ferro (71%. A biodisponibilidade de ferro da dieta foi de 8%. Observou-se baixo consumo de frutas, hortaliças e carnes, com consumo excessivo de leite de vaca e mingau.Our objective was to investigate nutritional status and complementary feeding practices in children from 6 to 24 months of age living in the Western Brazilian Amazon. A cross-sectional study was conducted within an urban area of Acrelândia, Acre State. A total of 164 children were studied. Prevalence rates for stunting and anemia were 12% and 40%, respectively, and overall prevalence of iron deficiency was 85%. Vitamin A and B12 serum levels were below normal thresholds in 15% and 12% of children, respectively. Low intake was observed for the following nutrients (% of children: folic acid (33%, vitamin C (40%, vitamin A (42%, zinc (46%, and iron (71%. Iron bioavailability in the diet was approximately 8%. Very low dietary intakes of fruits, vegetables, and meats were observed, in contrast with excessive consumption of cow's milk and porridge.

  17. QUIESST: mid-term progress report

    NARCIS (Netherlands)

    Clairbois, J.-P.; Roo, F. de; Garai, M.; Conter, M.; Defrance, J.; Oltean-Dumbrava, C.; Fusco, I.

    2011-01-01

    The research QUIESST (QUIetening the Environment of Sustainable Surface Transport) successfully started in November 2009 for 36 months, its objectives and work schedule have already been presented at the INTERNOISE 2010 Congress. This paper will present the progress report at mid-term (18 months):

  18. Progression and effect of cognitive-behavioral changes in patients with amyotrophic lateral sclerosis.

    Science.gov (United States)

    Bock, Meredith; Duong, Y-Nhy; Kim, Anthony; Allen, Isabel; Murphy, Jennifer; Lomen-Hoerth, Catherine

    2017-12-01

    To prospectively evaluate the progression of cognitive-behavioral function in amyotrophic lateral sclerosis (ALS) and examine the association of cognitive-behavioral deficits with disease progression, patient quality of life (QOL), and caregiver burden. We evaluated cognitive-behavioral function using the Amyotrophic Lateral Sclerosis Cognitive Behavioral Screen at enrollment and after 7 months in a cohort of patients with ALS. Paired t tests were used to evaluate the change in the 2 assessments. Linear regression and Kruskal-Wallis tests were applied to investigate how initial cognitive or behavioral status related to outcomes. The mean test-retest interval was 6.8 months (SD 1.6). Cognitive status of the study population (n = 49) overall did not change over the study period ( p = 0.06) despite progression of motor weakness ( p cognitive change. Patients initially classified as behaviorally normal showed increased behavioral problems over time ( t = -2.8, p = 0.009). Decline in cognitive (β = -1.3, p = 0.03) and behavioral (β = -0.76, p = 0.002) status predicted increasing caregiver burden. Behavioral abnormalities predicted decline in forced vital capacity and ALS Functional Rating Scale-Revised score ( p = 0.008, 0.012) in the study population and patient QOL in the most severely affected group ( t = 4.3, p = 0.003). Cognitive-behavioral change is a key aspect of disease heterogeneity in ALS. Executive function in ALS overall remains stable over 7 months as detected by an administered screening tool. However, patients may develop caregiver-reported behavioral symptoms in that time period. Screening for caregiver-reported symptoms has a particular utility in predicting future clinical decline, increased caregiver burden, and worsening patient QOL.

  19. Progressive necrotic encephalopathy following tacrolimus therapy for liver transplantation.

    Science.gov (United States)

    Aridon, Paolo; Ragonese, Paolo; Di Benedetto, Norma; Grasso, Giovanni; Conaldi, Pier Giulio; D'Amelio, Marco; Savettieri, Giovanni

    2009-12-01

    Previously described neurologic damage induced by immunosuppressive treatments includes transient or reversible central nervous system involvement. We describe a 57-year-old man who underwent liver transplantation and was started on immunosuppressive therapy with tacrolimus (FK506). Six months later, he started complaining of a progressive motor and sensory impairment of the left side, together with cognitive impairment. Brain MRI showed an enlarging lesion of the white matter with peripheral contrast enhancement. PET study indicated severe hypometabolism in the right hemisphere and spectroscopic MRI showed a peak of choline and relative reduction of other metabolites. Findings of CSF examinations and cultures, serology, and molecular techniques were normal. Tacrolimus treatment was stopped. A cerebral biopsy of the lesion showed a sub acute necrotizing process. In the following months, cognitive status of the patient tended to improve although he remained hemiplegic, while serial MRI confirmed the tendency to the recovery of the lesion that was still present 1 year after. The present observation describes a progressive encephalopathy associated with immune suppression with an unusual feature and permanent brain damage.

  20. Climate Prediction Center - monthly Outlook

    Science.gov (United States)

    Weather Service NWS logo - Click to go to the NWS home page Climate Prediction Center Site Map News Outlooks monthly Climate Outlooks Banner OFFICIAL Forecasts June 2018 [UPDATED MONTHLY FORECASTS SERVICE ) Canonical Correlation Analysis ECCA - Ensemble Canonical Correlation Analysis Optimal Climate Normals

  1. Monthly energy review, January 1999

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1999-01-01

    The Monthly Energy Review (MER) presents an overview of the Energy Information Administration`s recent monthly energy statistics. The statistics cover the major activities of US production, consumption, trade, stocks, and prices for petroleum, natural gas, coal, electricity, and nuclear energy. Also included are international energy and thermal and metric conversion factors. 37 figs., 61 tabs.

  2. Monthly energy review, July 1998

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1998-07-01

    The Monthly Energy Review (MER) presents an overview of the Energy Information Administration`s recent monthly energy statistics. The statistics cover the major activities of US production, consumption, trade, stocks, and prices for petroleum, natural gas, coal, electricity, and nuclear energy. Also included are international energy and thermal and metric conversion factors. 37 figs. 73 tabs.

  3. Monthly energy review, May 1999

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1999-05-01

    The Monthly Energy Review (MER) presents an overview of the Energy Information Administration`s recent monthly energy statistics. The statistics cover the major activities of US production, consumption, trade, stocks, and prices for petroleum, natural gas, coal, electricity, and nuclear energy. Also included are international energy and thermal and metric conversion factors. 37 figs., 61 tabs.

  4. Monthly energy review, March 1999

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1999-03-01

    The Monthly Energy Review (MER) presents an overview of the Energy Information Administration`s recent monthly energy statistics. The statistics cover the major activities of US production, consumption, trade, stocks, and prices for petroleum, natural gas, coal, electricity, and nuclear energy. Also included are international energy and thermal and metric conversion factors. 37 figs., 74 tabs.

  5. Monthly energy review, November 1997

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1997-11-01

    The Monthly Energy Review (MER) presents an overview of the Energy Information Administration`s recent monthly energy statistics. The statistics cover the major activities of US production, consumption, trade, stocks, and prices for petroleum, natural gas, coal, electricity, and nuclear energy. Also included are international energy and thermal and metric conversion factors. 37 figs., 91 tabs.

  6. Monthly energy review, June 1998

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1998-06-01

    The Monthly Energy Review (MER) presents an overview of the Energy Information Administration`s recent monthly energy statistics. The statistics cover the major activities of US production, consumption, trade, stocks, and prices for petroleum, natural gas, coal, electricity, and nuclear energy. Also included are international energy and thermal and metric conversion factors. 36 figs., 61 tabs.

  7. Monthly energy review, February 1999

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1999-02-01

    The Monthly Energy Review (MER) presents an overview of the Energy Information Administration`s recent monthly energy statistics. The statistics cover the major activities of US production, consumption, trade, stocks, and prices for petroleum, natural gas, coal, electricity, and nuclear energy. Also included are international energy and thermal and metric conversion factors. 37 figs., 73 tabs.

  8. Monthly energy review, November 1998

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1998-11-01

    The Monthly Energy Review (MER) presents an overview of the Energy Information Administration`s recent monthly energy statistics. The statistics cover the major activities of US production, consumption, trade, stocks, and prices for petroleum, natural gas, coal, electricity, and nuclear energy. Also included are international energy and thermal and metric conversion factors. 37 figs., 61 tabs.

  9. Monthly energy review, October 1998

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1998-10-01

    The Monthly Energy Review (MER) presents an overview of the Energy Information Administration`s recent monthly energy statistics. The statistics cover the major activities of US production, consumption, trade, stocks, and prices for petroleum, natural gas, coal, electricity, and nuclear energy. Also included are international energy and thermal and metric conversion factors. 37 figs., 61 tabs.

  10. ULTRAPLATE 30 month management report

    DEFF Research Database (Denmark)

    Jensen, Jens Dahl

    2003-01-01

    In the period from month 24 to month 30 focus has been on the work-package 3 activities concerning optimisation of the newly developed ULTRAPLATE technology towards specific industrial applications. Three main application areas have been pursued: 1) High- speed plating of lead free solder contacts...

  11. Status epilepticus

    NARCIS (Netherlands)

    Hensiek, AE; Absalom, Anthony

    2006-01-01

    Status epilepticus is defined as epileptic activity that continues for more than 30 minutes as a single seizure or as recurrent seizures without inter-ictal return of consciousness. The seizure activity is usually classified as partial or generalized. Although status epilepticus is an uncommon

  12. MHD Technology Transfer, Integration and Review Committee. Seventh semi-annual status report, April 1991--September 1991

    Energy Technology Data Exchange (ETDEWEB)

    1993-02-01

    This seventh semi-annual status report of the MHD Technology Transfer, Integration and Review Committee (TTIRC) summarizes activities of the TTIRC during the period April 1991 through September 1991. It includes a summary and minutes of the General Committee meeting, progress summaries of ongoing POC contracts, discussions pertaining to technical integration issues in the POC program, and planned activities for the next six months. The meeting included test plan with Western coal, seed regeneration economics, power management for the integrated topping cycle and status of the Clean Coal Technology Proposal activities. Appendices cover CDIF operations HRSR development, CFFF operations etc.

  13. Natural gas monthly, May 1997

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1997-05-01

    The Natural Gas Monthly highlights activities, events, and analyses of interest to public and private sector organizations associated with the natural gas industry. Volume and price data are presented each month for natural gas production, distribution, consumption, and interstate pipeline activities. Producer-related activities and underground storage data are also reported. From time to time, the NGM features articles designed to assist readers in using and interpreting natural gas information. The feature article this month is ``Restructuring energy industries: Lessons from natural gas.`` 6 figs., 26 tabs.

  14. Natural gas monthly, June 1994

    Energy Technology Data Exchange (ETDEWEB)

    1994-06-01

    The Natural Gas Monthly (NGM) highlights activities, events, and analyses of interest to public and private sector organizations associated with the natural gas industry. Volume and price data are presented each month for natural gas production, distribution, consumption, and interstate pipeline activities. Producer-related activities and underground storage data are also reported. From time to time, the NGM features articles designed to assist readers in using and interpreting natural gas information. The feature article this month is the executive summary from Natural Gas 1994: Issues and Trends. 6 figs., 31 tabs.

  15. The development of android - based children's nutritional status monitoring system

    Science.gov (United States)

    Suryanto, Agus; Paramita, Octavianti; Pribadi, Feddy Setio

    2017-03-01

    The calculation of BMI (Body Mass Index) is one of the methods to calculate the nutritional status of a person. The BMI calculation has not yet widely understood and known by the public. In addition, people should know the importance of progress in the development of child nutrition each month. Therefore, an application to determine the nutritional status of children based on Android was developed in this study. This study restricted the calculation for children with the age of 0-60 months. The application can run on a smartphone or tablet PC with android operating system due to the rapid development of a smartphone or tablet PC with android operating system and many people own and use it. The aim of this study was to produce a android app to calculate of nutritional status of children. This study was Research and Development (R & D), with a design approach using experimental studies. The steps in this study included analyzing the formula of the Body Mass Index (BMI) and developing the initial application with the help of a computer that includes the design and manufacture of display using Eclipse software. This study resulted in android application that can be used to calculate the nutritional status of children with the age 0-60 months. The results of MES or the error calculation analysis using body mass index formula was 0. In addition, the results of MAPE percentage was 0%. It shows that there is no error in the calculation of the application based on the BMI formula. The smaller value of MSE and MAPE leads to higher level of accuracy.

  16. Neurodevelopmental status of infants and young children treated for brain tumors with preirradiation chemotherapy

    International Nuclear Information System (INIS)

    Mulhern, R.K.; Horowitz, M.E.; Kovnar, E.H.; Langston, J.; Sanford, R.A.; Kun, L.E.

    1989-01-01

    In an effort to reduce the severity of late neurotoxicities associated with cranial irradiation, 14 infants and young children with malignant brain tumors were given preirradiation chemotherapy for 2 to 22 months (median, 8 months). Prospective neurodevelopmental evaluations were routinely conducted and now extend from 35 to 60 months (median, 41 months) postdiagnosis, and 10 to 52 months (median, 31 months) postirradiation in the 12 surviving children. At the initiation of chemotherapy, less than one fourth of the patients displayed normal performance status or mental functioning on age-corrected tests; the majority remained stable or declined while receiving chemotherapy. Declining mental development and adaptive behavior were noted in six patients following radiation therapy with only two patients now functioning in the normal range for age. The analysis suggests that neurodevelopmental progress is a function of multiple factors, including neurologic and sensorimotor deficits associated with the tumor, surgical intervention, and chemotherapy that antedated radiation therapy. This implies that delaying irradiation will not necessarily improve the patients' functional status. Whether the interval of postponement of irradiation evidenced in this sample will translate into an ultimately better quality of life remains unknown. Given the probable interaction of multiple risk factors, well-controlled prospective clinical trials are needed to definitively analyze this issue

  17. Your Baby's Growth: 12 Months

    Science.gov (United States)

    ... Safe Videos for Educators Search English Español Your Baby's Growth: 12 Months KidsHealth / For Parents / Your Baby's ... doubled his or her birth weight. Is My Baby Growing Normally? Babies' growth begins to slow as ...

  18. Developmental milestones record - 4 months

    Science.gov (United States)

    ... are expected to develop certain physical and mental skills. These skills are called milestones. Information All children develop a ... your child's health care provider. PHYSICAL AND MOTOR SKILLS The typical 4-month-old baby should: Slow ...

  19. Your Child's Development: 1 Month

    Science.gov (United States)

    ... Child’s Development: 1 Month Print en español El desarrollo de su hijo: 1 mes Have you ever ... lying on the tummy, holds head up briefly Social and Emotional Development recognizes mother's voice when upset, ...

  20. Your Child's Development: 2 Months

    Science.gov (United States)

    ... Child's Development: 2 Months Print en español El desarrollo de su hijo: 2 meses Your baby develops ... pose) fists remain unclenched half of the time Social and Emotional Development comforts himself or herself, maybe ...

  1. Your Child's Development: 6 Months

    Science.gov (United States)

    ... Child's Development: 6 Months Print en español El desarrollo de su hijo: 6 meses Notice your baby ... both ways (back to front, front to back) Social and Emotional Development recognizes and responds happily to ...

  2. Your Child's Development: 15 Months

    Science.gov (United States)

    ... Child's Development: 15 Months Print en español El desarrollo de su hijo: 15 meses Toddlers this age ... stacks three blocks scribbles with crayon on paper Social and Emotional Development begins to show preference for ...

  3. Monthly energy review, July 1997

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1997-07-01

    This document presents an overview of recent monthly energy statistics. Activities covered include: U.S. production, consumption, trade, stock, and prices for petroleum, coal, natural gas, electricity, and nuclear energy.

  4. Developmental milestones record - 12 months

    Science.gov (United States)

    ... to 2 naps during the day SENSORY AND COGNITIVE DEVELOPMENT The typical 12-month-old: Begins pretend play ( ... Editorial team. Infant and Newborn Development Read more Toddler Development Read more NIH MedlinePlus Magazine Read more A. ...

  5. Developmental milestones record - 18 months

    Science.gov (United States)

    ... The typical 18-month-old: Shows affection Has separation anxiety Listens to a story or looks at pictures Can say 10 or more words when asked Kisses parents with lips puckered Identifies one or more parts ...

  6. Monthly energy review, May 1990

    International Nuclear Information System (INIS)

    1990-01-01

    This document is a monthly report of Energy Information Administration on production, consumption, stocks, imports, and prices of the principal energy commodities in the United States. International energy data is also presented. 47 figs., 67 tabs

  7. Natural gas monthly, October 1998

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1998-10-01

    The Natural Gas Monthly (NGM) highlights activities, events, and analyses of interest to public and private sector organizations associated with the natural gas industry. Volume and price data are presented each month for natural gas production, distribution, consumption, and interstate pipeline activities. Producer-related activities and underground storage data are also reported. From time to time, the NGM features articles designed to assist readers in using and interpreting natural gas information. 6 figs., 27 tabs.

  8. Natural gas monthly, May 1999

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1999-05-01

    The Natural Gas Monthly (NGM) highlights activities, events, and analyses of interest to public and private sector organizations associated with the natural gas industry. Volume and price data are presented each month for natural gas production, distribution, consumption, and interstate pipeline activities. Producer-related activities and underground storage data are also reported. From time to time the NGM features articles designed to assist readers in using and interpreting natural gas information. 6 figs., 27 tabs.

  9. Natural gas monthly, June 1998

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1998-06-01

    The Natural Gas Monthly (NGM) highlights activities, events, and analyses of interest to public and private sector organizations associated with the natural gas industry. Volume and price data are presented each month for natural gas production, distribution, consumption, and interstate pipeline activities. Producer-related activities and underground storage data are also reported. From time to time, the NGM features articles designed to assist readers in using and interpreting natural gas information. 6 figs., 27 tabs.

  10. Monthly energy review, April 1999

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1999-04-01

    The Monthly Energy Review (MER) presents an overview of the Energy Information Administration`s recent monthly energy statistics. The statistics cover the major activities of US production, consumption, trade, stocks, and prices for petroleum, natural gas, coal, electricity, and nuclear energy. Also included are international energy and thermal and metric conversion factors. The MER is intended for use by Members of Congress, Federal and State agencies, energy analysts, and the general public.

  11. Electric Power Monthly, March 1991

    International Nuclear Information System (INIS)

    1991-01-01

    The Electric Power Monthly (EPM) presents monthly summaries of electric utility statistics at the national, Census division, and state level. The purpose of this publication is to provide energy decisionmakers with accurate and timely information that may be used in forming various perspectives on electric issues that lie ahead. Data are presented on generation, fuel consumption, stockpiles, costs, sales, and unusual occurrences. Fuels considered are: coal, petroleum, natural gas, nuclear power, and hydroelectric power. 4 figs., 48 tabs

  12. Monthly energy review, August 1998

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1998-08-01

    The Monthly Energy Review (MER) presents an overview of the Energy Information Administration`s recent monthly energy statistics. The statistics cover the major activities of US production, consumption, trade, stocks, and prices for petroleum, natural gas, coal, electricity, and nuclear energy. Also included are international energy and thermal and metric conversion factors. The MER is intended for use by Members of Congress, Federal and State agencies, energy analysts, and the general public. 37 figs., 73 tabs.

  13. Natural gas monthly, August 1994

    Energy Technology Data Exchange (ETDEWEB)

    1994-08-24

    The Natural Gas Monthly (NGM) highlights activities, events, and analyses of interest to public and private sector organizations associated with the natural gas industry. Volume and price data are presented each month for natural gas production, distribution, consumption, and interstate pipeline activities. Producer-related activities and underground storage data are also reported. From time to time, the NGM features articles designed to assist readers in using and interpreting natural gas information.

  14. Natural gas monthly, November 1993

    International Nuclear Information System (INIS)

    1993-01-01

    The Natural Gas Monthly (NGM) highlights activities, events, and analyses of interest to public and private sector organizations associated with the natural gas industry. Volume and price data are presented each month for natural gas production, distribution, consumption, and interstate pipeline activities. Producer-related activities and underground state data are also reported. From time to time, the NGM features articles designed to assist readers in using and interpreting natural gas information

  15. Stock Status

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — These data inform the public of the most recent stock status for all stocks (FSSI and non-FSSI) in the fishery management unit contained in a fishery managment plan....

  16. Hanford Laboratories Operation monthly activities report, September 1956

    Energy Technology Data Exchange (ETDEWEB)

    1956-10-19

    This is the monthly report for the Hanford Laboratories Operation. Metallurgy, reactor fuels, physics and instrumentation, reactor technology, chemistry, separation processes, biology, financial activities, employee relations, laboratories auxiliaries, radiation protection, operation research, inventions, visits, and personnel status are discussed. This report is for September 1956.

  17. Hanford Laboratories operation monthly activities report, November 1956

    Energy Technology Data Exchange (ETDEWEB)

    1956-12-21

    This is the monthly report for the Hanford Laboratories Operation. Metallurgy, reactor fuels, physics and instrumentation, reactor technology, chemistry, separation processes, biology, financial activities, employee relations, laboratories auxiliaries, radiation protection, operations research, inventions, visits, and personnel status are discussed. This report is for November, 1956.

  18. Hanford Laboratories Operation monthly activities report, October 1958

    Energy Technology Data Exchange (ETDEWEB)

    1958-11-15

    This is the monthly report for the Hanford Laboratories Operation. Metallurgy, reactor fuels, physics and instrumentation, reactor technology, chemistry, separation processes, biology, financial activities, employee relations, laboratories auxiliaries, radiation protection, operation research, inventions, visits, and personnel status are discussed. This report is for October 1958.

  19. Hanford Laboratories operation monthly activities report, November 1957

    Energy Technology Data Exchange (ETDEWEB)

    1957-12-15

    This is the monthly report for the Hanford Laboratories Operation. Metallurgy, reactor fuels, physics and instrumentation, reactor technology, chemistry, separation processes, biology, financial activities, employee relations, laboratories auxiliaries, radiation protection, operation research, inventions, visits, and personnel status are discussed. This report is for November 1957.

  20. Hanford Laboratories Operation monthly activities report, October 1957

    Energy Technology Data Exchange (ETDEWEB)

    1957-11-15

    This is the monthly report for the Hanford Laboratories Operation. Metallurgy, reactor fuels, physics and instrumentation, reactor technology, chemistry, separation processes, biology, financial activities, employee relations, laboratories auxiliaries, radiation protection, operation research, inventions, visits, and personnel status are discussed. This report is for October 1957.

  1. Hanford Laboratories operation monthly activities report, January 1957

    Energy Technology Data Exchange (ETDEWEB)

    1957-02-15

    This is the monthly report for the Hanford Laboratories Operation. Metallurgy, reactor fuels, physics and instrumentation, reactor technology, chemistry, separation processes, biology, financial activities, employee relations, laboratories auxiliaries, radiation protection, operation research, inventions, visits, and personnel status are discussed. This report is for January 1957.

  2. Hanford Laboratories Operation monthly activities report, March 1960

    Energy Technology Data Exchange (ETDEWEB)

    1960-04-15

    This is the monthly report for the Hanford Laboratories Operation. Metallurgy, reactor fuels, physics and instrumentation, reactor technology, chemistry, separation processes, biology, financial activities, employee relations, laboratories auxiliaries, radiation protection, operation research, inventions, visits, and personnel status are discussed. This report is for March 1960.

  3. Hanford Laboratories operation monthly activities report, February 1958

    Energy Technology Data Exchange (ETDEWEB)

    1958-03-15

    This is the monthly report for the Hanford Laboratories Operation. Metallurgy, reactor fuels, physics and instrumentation, reactor technology, chemistry, separation processes, biology, financial activities, employee relations, laboratories auxiliaries, radiation protection, operation research, inventions, visits, and personnel status are discussed. This report is for February 1958.

  4. Hanford Laboratories Operation monthly activities report, December 1957

    Energy Technology Data Exchange (ETDEWEB)

    1958-01-15

    This is the monthly report for the Hanford Laboratories Operation. Metallurgy, reactor fuels, physics and instrumentation, reactor technology, chemistry, separation processes, biology, financial activities, employee relations, laboratories auxiliaries, radiation protection, operation research, inventions, visits, and personnel status are discussed. This report is for December 1957.

  5. Geothermal progress monitor report No. 6

    Energy Technology Data Exchange (ETDEWEB)

    1982-06-01

    Geothermal Progress Monitor Report No. 6 presents a state-by-state summary of the status of geothermal leasing, exploration, and development in major physiographic regions where geothermal resource potential has been identified. Recent state-specific activities are reported at the end of each state status report, while recent activities of a more general nature are summarized briefly in Part II of the report. A list of recent publications of potential interest to the geothermal community and a directory of contributors to the geothermal progress monitoring system are also included.

  6. Solar lease grant program. Technical progress report

    Energy Technology Data Exchange (ETDEWEB)

    1981-04-01

    Progress on a lease program for the installation of a solar water heater with no installation charge is reported. Information on the announcement of the program, the selection of participants, the contractural agreement, progress on installation of equipment, monitoring, and evaluation is summarized. The status of the budget concerned with the program is announced. Forms used for applications for the program and an announcement from Resource Alternatives for Cilco customers are presented.

  7. Association between food consumption in the first months of life and socioeconomic status: a longitudinal study Associação entre consumo alimentar nos primeiros meses de vida e condições socioeconômicas: um estudo longitudinal

    Directory of Open Access Journals (Sweden)

    Edson Theodoro dos Santos Neto

    2009-10-01

    Full Text Available OBJECTIVE: This paper aims to describe the quality of the feeding practices of infants from the moment liquids and semi-solid foods are introduced into their diets and to determine associations between feeding practices and socioeconomic status. METHODS: The initial population consisted of 86 infants aged 0 to 3 months; they were selected from 3 Public Primary Healthcare Units of the city of Vitória. Seven visits were made to the children's homes to collect descriptive data on the mother, house, eating habits and sucking habits. Chi-square tests were applied and logistic regression analysis was performed to measure the associations. RESULTS: Approximately 50% of the children were given bottles before age 3 months, while semi-solid foods were given to 75% of the infants aged 6 months or less. Logistic regression models showed that the lack of paternal contribution to the family's income is a risk factor for the consumption of beans (OR =3.9; CI - 95% =1.2-12.6. Family income equal to or above two minimum wages was likely to promote fruit consumption (OR =0.4: CI - 95%=0.14-1.15. CONCLUSION: Food variety percentages revealed that most children under two years of age were not being fed properly. The mother's education level and contribution of the father to family income seem to influence the consumption of certain foods, such as fruits and beans. However, they do not fully explain the feeding practices found in the first months of life, showing that other more complex issues may be involved.OBJETIVO: Objetivou-se descrever a qualidade do consumo alimentar de crianças a partir da inclusão da alimentação complementar líquida e semi-sólida, nos primeiros meses de vida, além de determinar as associações entre as práticas alimentares e as condições socioeconômicas. MÉTODOS: O grupo inicial constituiu-se por 86 bebês com idades de 0 a 3 meses, selecionados em áreas de abrangência de três Unidades Básicas de Saúde do Município de

  8. Radiographic progression with nonrising PSA in metastatic castration-resistant prostate cancer: post hoc analysis of PREVAIL.

    Science.gov (United States)

    Bryce, A H; Alumkal, J J; Armstrong, A; Higano, C S; Iversen, P; Sternberg, C N; Rathkopf, D; Loriot, Y; de Bono, J; Tombal, B; Abhyankar, S; Lin, P; Krivoshik, A; Phung, D; Beer, T M

    2017-06-01

    Advanced prostate cancer is a phenotypically diverse disease that evolves through multiple clinical courses. PSA level is the most widely used parameter for disease monitoring, but it has well-recognized limitations. Unlike in clinical trials, in practice, clinicians may rely on PSA monitoring alone to determine disease status on therapy. This approach has not been adequately tested. Chemotherapy-naive asymptomatic or mildly symptomatic men (n=872) with metastatic castration-resistant prostate cancer (mCRPC) who were treated with the androgen receptor inhibitor enzalutamide in the PREVAIL study were analyzed post hoc for rising versus nonrising PSA (empirically defined as >1.05 vs ⩽1.05 times the PSA level from 3 months earlier) at the time of radiographic progression. Clinical characteristics and disease outcomes were compared between the rising and nonrising PSA groups. Of 265 PREVAIL patients with radiographic progression and evaluable PSA levels on the enzalutamide arm, nearly one-quarter had a nonrising PSA. Median progression-free survival in this cohort was 8.3 months versus 11.1 months in the rising PSA cohort (hazard ratio 1.68; 95% confidence interval 1.26-2.23); overall survival was similar between the two groups, although less than half of patients in either group were still at risk at 24 months. Baseline clinical characteristics of the two groups were similar. Non-rising PSA at radiographic progression is a common phenomenon in mCRPC patients treated with enzalutamide. As restaging in advanced prostate cancer patients is often guided by increases in PSA levels, our results demonstrate that disease progression on enzalutamide can occur without rising PSA levels. Therefore, a disease monitoring strategy that includes imaging not entirely reliant on serial serum PSA measurement may more accurately identify disease progression.

  9. Metronomic Chemotherapy vs Best Supportive Care in Progressive Pediatric Solid Malignant Tumors: A Randomized Clinical Trial.

    Science.gov (United States)

    Pramanik, Raja; Agarwala, Sandeep; Gupta, Yogendra Kumar; Thulkar, Sanjay; Vishnubhatla, Sreenivas; Batra, Atul; Dhawan, Deepa; Bakhshi, Sameer

    2017-09-01

    Although oral metronomic chemotherapy is often used in progressive pediatric solid malignant tumors, a literature review reveals that only small single-arm retrospective or phase 1 and 2 studies have been performed. Skepticism abounds because of the lack of level 1 evidence. To compare the effect of metronomic chemotherapy on progression-free survival (PFS) with that of placebo in pediatric patients with primary extracranial, nonhematopoietic solid malignant tumors that progress after at least 2 lines of chemotherapy. A double-blinded, placebo-controlled randomized clinical trial was conducted from October 1, 2013, through December 31, 2015, at the cancer center at All India Institute of Medical Sciences in children aged 5 to 18 years with primary extracranial, nonhematopoietic solid malignant tumors that progressed after at least 2 lines of chemotherapy and had no further curative options. One arm received a 4-drug oral metronomic regimen of daily celecoxib and thalidomide with alternating periods of etoposide and cyclophosphamide, whereas the other arm received placebo. Disease status was assessed at baseline, 9 weeks, 18 weeks, and 27 weeks or at clinical progression. The primary end point was PFS as defined by the proportion of patients without disease progression at 6 months, and PFS duration and overall survival (OS) were secondary end points. A total of 108 of the 123 patients screened were enrolled, with 52 randomized to the placebo group (median age, 15 years; 40 male [76.9%]) and 56 to the metronomic chemotherapy group (median age, 13 years; 42 male [75.0%]). At a median follow-up of 2.9 months, 100% of the patients had disease progression by 6 months in the placebo group vs 96.4% in the metronomic chemotherapy group (P = .24). Median PFS and OS in the 2 groups was similar (hazard ratio [HR], 0.69; 95% CI, 0.47-1.03 [P = .07] for PFS; and HR, 0.74; 95% CI, 0.50-1.09 [P = .13] for OS). In post hoc subgroup analysis, cohorts receiving more than

  10. December 2012 imaging case of the month

    Directory of Open Access Journals (Sweden)

    Gotway MB

    2012-12-01

    Full Text Available No abstract available. Article truncated after first page. Clinical History: A 35-year-old non-smoking man presented with a history of slowly progressive shortness of breath preceded by cough and wheezing, previously presumptively diagnosed with asthma. He had a previous history of ulcerative colitis and a +PPD for which he received 6 month INH therapy. Frontal and lateral chest radiography (Figure 1 was performed.Figure 1. Panel A: Frontal chest radiography. Panel B: Lateral chest radiography. Which of the following statements regarding the chest radiograph is accurate? 1.The radiograph shows a diffuse interstitial abnormality 2.The radiograph appears normal 3.The radiograph shows cystic lung disease 4.The radiograph a mediastinal contour abnormality 5.The radiograph shows abnormal lung volumes

  11. Low-dose fractionated radiotherapy and concomitant chemotherapy for recurrent or progressive glioblastoma. Final report of a pilot study

    Energy Technology Data Exchange (ETDEWEB)

    Balducci, M.; Diletto, B.; Chiesa, S.; D' Agostino, G.R.; Gambacorta, M.A.; Ferro, M.; Valentini, V. [Catholic University of the Sacred Heart, Department of Radiation Oncology, Rome (Italy); Colosimo, C. [Catholic University of the Sacred Heart, Department of Radiology, Rome (Italy); Maira, G.; Anile, C. [Catholic University of the Sacred Heart, Department of Neurosurgery, Rome (Italy)

    2014-04-15

    Evaluated in this study were the feasibility and the efficacy of concurrent low dose fractionated radiotherapy (LD-FRT) and chemotherapy as palliative treatment for recurrent/progressive glioblastoma multiforme (GBM). Eligible patients had recurrent or progressive GBM, Karnofsky performance status ≥70, prior surgery, and standard radiochemotherapy treatment. Recurrence/progression disease during temozolomide (TMZ) received cisplatin (CDDP; 30 mg/m{sup 2} on days 1, 8, 15), fotemustine (FTM; 40 mg/m{sup 2} on days 2, 9, 16), and concurrent LD-FRT (0.3 Gy twice daily); recurrence/progression after 4 months from the end of adjuvant TMZ were treated by TMZ (150/200 mg/m{sup 2} on days 1-5) concomitant with LD-FRT (0.4 Gy twice daily). Primary endpoints were safety and toxicity. A total of 32 patients were enrolled. Hematologic toxicity G1-2 was observed in 18.7% of patients and G3-4 in 9.4%. One patient (3.1%) had complete response, 3 (9.4%) had partial response, 8 (25%) had stable disease for at least 8 weeks, while 20 patients (62.5%) experienced progressive disease. The clinical benefit was 37.5%. Median progression-free survival (PFS) and overall survival (OS) were 5 and 8 months, respectively. Survival rate at 12 months was of 27.8%. LD-FRT and chemotherapy for recurrent/progressive GBM have a good toxicity profile and clinical outcomes, even though further investigation of this novel palliative treatment approach is warranted. (orig.)

  12. Status and neutron scattering experiments at KENS

    International Nuclear Information System (INIS)

    Watanabe, N.; Sasaki, H.; Ishikawa, Y.; Endoh, Y.; Inoue, K.

    1983-01-01

    This paper reports present status of the KENS facility, progress in neutron scattering experiments and instrumental developments, and status of the KENS-I' program. A design study of a high intensity rapid-cycle 800 MeV proton synchrotron for proposed new pulsed neutron (KENS-II) and meson source is also descirbed

  13. Progression of chronic renal failure.

    Science.gov (United States)

    Hakim, R M; Lazarus, J M

    1989-11-01

    Rates of progression of renal failure were calculated for a group of 277 patients who had five or more clinic visits. The goals of therapy in the absence of ongoing immunological processes were control of blood pressure to diastolic pressures less than 85 mm Hg and serum phosphate less than 1.60 mmol/L (5 mg/dL). The mean rate of progression expressed as the slope of the reciprocal creatinine versus time was -0.0054 +/- 0.0009 dL/mg/mo (mean +/- SEM), and the median was -0.00315 dL/mg/mo. Approximately 25% of these patients had rates of progression less than -0.001 dL/mg/mo. The rate of progression was inversely correlated with the creatinine concentration at entry (P less than 0.004) and with the frequency of clinic visits (P less than 0.01). The "renal survival" time from a creatinine of 880 mumol/L (10 mg/dL) to dialysis was 10.0 +/- 1.2 months (mean +/- SEM). These data provide rates of progression for a group of patients without specific dietary intervention but with vigorous control of blood pressure and phosphorus.

  14. Electric power monthly, May 1994

    Energy Technology Data Exchange (ETDEWEB)

    1994-05-01

    The Electric Power Monthly (EPM) presents monthly electricity statistics. The purpose of this publication is to provide energy decisionmakers with accurate and timely information that may be used in forming various perspectives on electric issues that lie ahead. Data in this report are presented for a wide audience including Congress, Federal and State agencies, the electric utility industry, and the general public. This publication provides monthly statistics for net generation, fossil fuel consumption and stocks, quantity and quality of fossil fuels, cost of fossil fuels, electricity sales, revenue, and average revenue per kilowatthour of electricity sold. Statistics by company and plant are published on the capability of new generating units, net generation, fuel consumption, fuel stocks, quantity and quality of fuel, and cost of fossil fuels.

  15. Electric power monthly, April 1994

    Energy Technology Data Exchange (ETDEWEB)

    1994-04-01

    The Electric Power Monthly (EPM) presents monthly electricity statistics. The purpose of this publication is to provide energy decisionmakers with accurate and timely information that may be used in forming various perspectives on electric issues that lie ahead. This publication provides monthly statistics at the U.S., Census division, and State levels for net generation, fossil fuel consumption and stocks, quantity and quality of fossil fuels, cost of fossil fuels, electricity sales, revenue, and average revenue per kilowatthour of electricity sold. Data on net generation, fuel consumption, fuel stocks, quantity and cost of fossil fuels are also displayed for the North American Electric Reliability Council (NERC) regions. This April 1994 issue contains 1993 year-end data and data through January 1994.

  16. Electric power monthly, August 1993

    Energy Technology Data Exchange (ETDEWEB)

    1993-08-13

    The Electric Power Monthly (EPM) presents monthly electricity statistics. The purpose of this publication is to provide energy decisionmakers with accurate and timely information that may be used in forming various perspectives on electric issues that lie ahead. The EPM is prepared by the Survey Management Division; Office of Coal, Nuclear, Electric and Alternate Fuels, Energy Information Administration (EIA), Department of Energy. This publication provides monthly statistics at the US, Census division, and State levels for net generation, fossil fuel consumption and stocks, quantity and quality of fossil fuels, cost of fossil fuels, electricity sales, revenue, and average revenue per kilowatthour of electricity sold. Data on net generation, fuel consumption, fuel stocks, quantity and cost of fossil fuels are also displayed for the North American Electric Reliability Council (NERC) regions.

  17. Electric power monthly, September 1993

    Energy Technology Data Exchange (ETDEWEB)

    1993-09-17

    The Electric Power Monthly (EPM) presents monthly electricity statistics. The purpose of this publication is to provide energy decisionmakers with accurate and timely information that may be used in forming various perspectives on electric issues that lie ahead. The EPM is prepared by the Survey Management Division; Office of Coal, Nuclear, Electric and Alternate Fuels, Energy Information Administration (EIA), Department of Energy. This publication provides monthly statistics at the US, Census division, and State levels for net generation, fossil fuel consumption and stocks, quantity and quality of fossil fuels, cost of fossil fuels, electricity sales, revenue, and average revenue per kilowatthour of electricity sold. Data on net generation, fuel consumption, fuel stocks, quantity and cost of fossil fuels are also displayed for the North American Electric Reliability Council (NERC) regions.

  18. Petroleum marketing monthly, May 1994

    Energy Technology Data Exchange (ETDEWEB)

    1994-05-26

    The Petroleum Marketing Monthly (PMM) provides information and statistical data on a variety of crude oils and refined petroleum products. The publication presents statistics on crude oil costs and refined petroleum products sales for use by industry, government, private sector analysts, educational institutions, and consumers. Data on crude oil include the domestic first purchase price, the f.o.b. and landed cost of imported crude oil, petroleum product sales data include motor gasoline, distillates, residuals, aviation fuels, kerosene, and propane. The Petroleum Marketing Division, Office of Oil and Gas, Energy Information Administration ensures the accuracy, quality, and confidentiality of the published data in the Petroleum Marketing Monthly.

  19. Natural gas monthly, April 1999

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1999-05-06

    The Natural Gas Monthly (NGM) highlights activities, events, and analyses of interest to public and private sector organizations associated with the natural gas industry. Volume and price data are presented each month for natural gas production, distribution, consumption, and interstate pipeline activities. Producer-related activities and underground storage data are also reported. From time to time, the NGM features articles designed to assist readers in using and interpreting natural gas information. There are two feature articles in this issue: Natural gas 1998: Issues and trends, Executive summary; and Special report: Natural gas 1998: A preliminary summary. 6 figs., 28 tabs.

  20. Electric power monthly, April 1993

    Energy Technology Data Exchange (ETDEWEB)

    1993-05-07

    The Electric Power Monthly is prepared by the Survey Management Division; Office of Coal, Nuclear, Electric and Alternate Fuels, Energy Information Administration (EIA), Department of Energy. This publication provides monthly statistics at the US, Census division, and State levels for net generation, fossil fuel consumption and stocks, quantity and quality of fossil fuels, cost of fossil fuels, electricity sales, revenue, and average revenue per kilowatthour of electricity sold. Data on net generation, fuel consumption, fuel stocks, quantity and cost of fossil fuels are also displayed for the North American Electric Reliability Council (NERC) regions.

  1. Electric power monthly, June 1994

    Energy Technology Data Exchange (ETDEWEB)

    1994-06-01

    The Electric Power Monthly (EPM) presents monthly electricity statistics. The purpose of this publication is to provide energy decisionmakers with accurate and timely information that may be used in forming various perspectives on electric issues that lie ahead. Data in this report are presented for a wide audience including Congress, Federal and State agencies, the electric utility industry, and the general public. The EIA collected the information in this report to fulfill its data collection and dissemination responsibilities as specified in the Federal Energy Administration Act of 1974 (Public Law 93-275) as amended.

  2. Electric power monthly, August 1994

    Energy Technology Data Exchange (ETDEWEB)

    1994-08-24

    The Electric Power Monthly (EPM) presents monthly electricity statistics. The purpose of this publication is to provide energy decisionmakers with accurate and timely information that may be used in forming various perspectives on electric issues that lie ahead. Data in this report are presented for a wide audience including Congress, Federal and State agencies, the electric utility industry, and the general public. The EIA collected the information in this report to fulfill its data collection and dissemination responsibilities as specified in the Federal Energy Administration Act of 1974 (Public Law 93-275) as amended.

  3. Monthly energy review, June 1999

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1999-06-01

    The Monthly Energy Review (MER) presents an overview of the Energy Information Administration`s recent monthly energy statistics. The statistics cover the major activities of US production, consumption, trade, stocks, and prices for petroleum, natural gas, coal, electricity, and nuclear energy. Also included are international energy and thermal and metric conversion factors. The MER is intended for use by Members of Congress, Federal and State agencies, energy analysts, and the general public. EIA welcomes suggestions from readers regarding data series in the MER and in other EIA publications. 37 figs., 61 tabs.

  4. Monthly energy review, July 1999

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1999-07-01

    The Monthly Energy Review (MER) presents an overview of the Energy Information Administration`s recent monthly energy statistics. The statistics cover the major activities of US production, consumption, trade, stocks, and prices for petroleum, natural gas, coal, electricity, and nuclear energy. Also included are international energy and thermal and metric conversion factors. The MER is intended for use by Members of Congress, Federal and State agencies, energy analysts, and the general public. EIA welcomes suggestions from readers regarding data series in the MER and in other EIA publications. 37 figs., 75 tabs.

  5. Natural gas monthly, August 1993

    Energy Technology Data Exchange (ETDEWEB)

    1993-08-25

    The Natural Gas Monthly (NGM) is prepared in the Data Operations Branch of the Reserves and Natural Gas Division, Office of Oil and Gas, Energy Information Administration (EIA), US Department of Energy (DOE). The NGM highhghts activities, events, and analyses of interest to public and private sector organizations associated with the natural gas industry. Volume and price data are presented each month for natural gas production, distribution, consumption, and interstate pipeline activities. Producer-related activities and underground storage data are also reported. From time to time, the NGM features articles designed to assist readers in using and interpreting natural gas information.

  6. Electric power monthly, May 1993

    Energy Technology Data Exchange (ETDEWEB)

    1993-05-25

    The Electric Power Monthly (EPM) is prepared by the Survey Management Division; Office of Coal, Nuclear, Electric and Alternate Fuels, Energy Information Administration (EIA), Department of Energy. This publication provides monthly statistics at the US, Census division, and State levels for net generation, fossil fuel consumption and stocks, quantity and quality of fossil fuels, cost of fossil fuels, electricity sales, revenue, and average revenue per kilowatthour of electricity sold. Data on net generation, fuel consumption, fuel stocks, quantity and cost of fossil fuels are also displayed for the North American Electric Reliability Council (NERC) regions.

  7. Electric power monthly, July 1993

    Energy Technology Data Exchange (ETDEWEB)

    1993-07-29

    The Electric Power Monthly (EPM) presents monthly electricity statistics. The purpose of this publication is to provide energy decisionmakers with accurate and timely information that may be used in forming various perspectives on electric issues that lie ahead. Data in this report are presented for a wide audience including Congress, Federal and State agencies, the electric utility industry, and the general public. The EIA collected the information in this report to fulfill its data collection and dissemination responsibilities as specified in the Federal Energy Administration Act of 1974 (Public Law 93-275) as amended.

  8. Electric power monthly, November 1994

    International Nuclear Information System (INIS)

    1994-11-01

    The Electric Power Monthly (EPM) presents monthly electricity statistics. The purpose of this publication is to provide energy decisionmakers with accurate and timely information that may be used in forming various perspectives on electric issues that lie ahead. Data in this report are presented for a wide audience including Congress, Federal and State agencies, the electric utility industry, and the general public. The EIA collected the information in this report to fulfill its data collection and dissemination responsibilities as specified in the Federal Energy Administration Act of 1974 (Public Law 93-275) as amended

  9. Tunneling progress on the Yucca Mountain Project

    International Nuclear Information System (INIS)

    Hansmire, W.H.; Munzer, R.J.

    1996-01-01

    The current status of tunneling progress on the Yucca Mountain Project (YMP) is presented in this paper. The Exploratory Studies Facility (ESF), a key part of the YMP, has been long in development and construction is ongoing. This is a progress report on the tunneling aspects of the ESF as of January 1, 1996. For purposes of discussion in this summary, the tunneling has progressed in four general phases. The paper describes: tunneling in jointed rock under low stress; tunneling through the Bow Ridge Fault and soft rock; tunneling through the Imbricate Fault Zone; and Tunneling into the candidate repository formation

  10. CO{sub 2} emissions abatement and geologic sequestration - industrial innovations and stakes - status of researches in progress; Reduction des emissions et stockage geologique du CO{sub 2} - innovation et enjeux industriels - le point des recherches en cours

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2005-07-01

    This colloquium was jointly organized by the French institute of petroleum (IFP), the French agency of environmental and energy mastery (Ademe) and the geological and mining research office (BRGM). This press kit makes a status of the advances made in CO{sub 2} emissions abatement and geological sequestration: technological advances of CO{sub 2} capture and sequestration, geological reservoir dimensioning with respect to the problem scale, duration of such an interim solution, CO{sub 2} emissions abatement potentialities of geological sequestration, regulatory, economical and financial implications, international stakes of greenhouse gas emissions. This press kit comprises a press release about the IFP-Ademe-BRGM colloquium, a slide presentation about CO{sub 2} abatement and sequestration, and four papers: a joint IFP-Ademe-BRGM press conference, IFP's answers to CO{sub 2} emissions abatement, Ademe's actions in CO{sub 2} abatement and sequestration, and BRGM's experience in CO{sub 2} sequestration and climatic change expertise. (J.S.)

  11. Geothermal progress monitor. Progress report No. 1

    Energy Technology Data Exchange (ETDEWEB)

    1979-12-01

    Progress is reported on the following: electrical uses, direct-heat uses, drilling activities, leases, geothermal loan guarantee program, general activities, and legal, institutional, and regulatory activites. (MHR)

  12. Progress report, 1982

    International Nuclear Information System (INIS)

    1982-01-01

    The report describes a number of areas of research at the TRIUMPH facility. Substantial progress has been made in the experiment to measure charge symmetry breaking in the n-p system. The investigations on polarized nucleon radiative capture on light nuclei have been ongoing with results of the excitation function for p + d→γ + 3 He reaction being published. Studies of the n + p→d + γ reactions are continuing. Results have been obtained in the determination of structure in the three nucleon system by studying the reaction anti d + p using tensor polarized deuterons. The Wolfenstein R-parameter in proton - 4 He elastic scattering has been measured at 500 MeV from 15 to 50 degrees (lab.) using the focal plane polarimeter on the MRS. Other experiments involving quasi-elastic scattering of polarized protons at 300 MeV, fission evaporation competition in heavy nuclei and proton-proton bremsstrahlung have been carried out. The status of the Bevelac heavy ion collaboration and the MWPC facility is also included

  13. 4 months in 1 minute

    CERN Multimedia

    CERN Bulletin & the CERN Visual Media Office

    2013-01-01

    In Bulletin 49-50/2012 we published an article entitled “Stopping the haemorrhage” (to read the article, click here) about the installation of the new cryogenic infrastructure in SM18, in the part of the hall devoted to the testing of radiofrequency (RF) cavities and beam accelerator cryomodules. From December 2012 to March 2013, we have been following the progress of the work. Ready? Action!  

  14. Hepatitis Awareness Month PSA (:30)

    Centers for Disease Control (CDC) Podcasts

    2011-05-11

    May is National Hepatitis Awareness Month. This 30 second PSA discusses hepatitis and encourages listners to talk to their health care professional about getting tested.  Created: 5/11/2011 by National Center for HIV/AIDS, Viral Hepatitis, STD, and TB Prevention.   Date Released: 5/11/2011.

  15. Monthly energy review, June 1990

    Energy Technology Data Exchange (ETDEWEB)

    1990-09-26

    The Monthly Energy Review presents current data on production, consumption, stocks, imports, exports, and prices of the principal energy commodities in the United States. Also included are data on international production of crude oil, consumption of petroleum products, petroleum stocks, and production of electricity from nuclear-powered facilities.

  16. Electric Power Monthly, July 1990

    Energy Technology Data Exchange (ETDEWEB)

    1990-10-12

    The Electric Power Monthly (EPM) is prepared by the Electric Power Division; Office of Coal, Nuclear, Electric and Alternate Fuels, Energy Information Administration (EIA), Department of Energy. This publication provides monthly statistics at the national, Census division, and State levels for net generation, fuel consumption, fuel stocks, quantity and quality of fuel, cost of fuel, electricity sales, and average revenue per kilowatthour of electricity sold. Data on net generation are also displayed at the North American Electric Reliability Council (NERC) region level. Additionally, company and plant level information are published in the EPM on capability of new plants, net generation, fuel consumption, fuel stocks, quantity and quality of fuel, and cost in fuel. Quantity, quality, and cost of fuel data lag the net generation, fuel consumption, fuel stocks, electricity sales, and average revenue per kilowatthour data by 1 month. This difference in reporting appears in the national, Census division, and State level tables. However, at the plant level, all statistics presented are for the earlier month for the purpose of comparison. 12 refs., 4 figs., 48 tabs.

  17. Monthly energy review, November 1993

    Energy Technology Data Exchange (ETDEWEB)

    1993-11-24

    The Monthly Energy Review gives information on production, distribution, and consumption for various energy sources, e.g. petroleum, natural gas, oil, coal, electricity, and nuclear energy. Some data is also included on international energy sources and supplies, the import of petroleum products into the US and pricing and reserves data (as applicable) for the various sources of energy listed above.

  18. Natural gas monthly, July 1990

    Energy Technology Data Exchange (ETDEWEB)

    1990-10-03

    This report highlights activities, events, and analyses of interest to public and private sector organizations associated with the natural gas industry. Volume and price data are presented each month for natural gas production, distribution, consumption, and interstate pipeline activities. Producer-related activities and underground storage data are also reported. A glossary is included. 7 figs., 33 tabs.

  19. STD Awareness Month PSA (:30)

    Centers for Disease Control (CDC) Podcasts

    2011-04-19

    April is National STD Awareness Month. STDs can affect anyone. Many STDs don't have symptoms so it's important to get tested.  Created: 4/19/2011 by National Center for HIV/AIDS, Viral Hepatitis, STD, and TB Prevention.   Date Released: 4/19/2011.

  20. Monthly energy review, November 1994

    International Nuclear Information System (INIS)

    1994-11-01

    This monthly publication contains statistical data on energy resources in the United States. Petroleum, natural gas, coal, electricity, and nuclear energy are covered. Additional sections include an energy overview, energy consumption, oil and gas resource development and energy prices. This issue includes features on energy-related housing characteristics and the propane-provider fleet

  1. Monthly energy review, January 1996

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-01-01

    This document presents an overview of the Energy Information Administration`s recent monthly energy statistics. The statistics cover the major activities of U.S. production, consumption, trade, stocks, and prices for petroleum,natural gas, coal, electricity, and nuclear energy. Also included are international energy and thermal metric conversion factors.

  2. Electric power monthly, March 1995

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1995-03-20

    This report for March 1995, presents monthly electricity statistics for a wide audience including Congress, Federal and State agencies, the electric utility industry, and the general public. The purpose of this publication is to provide energy decisionmakers with accurate and timely information that may be used in forming various perspectives on electric issues that lie ahead.

  3. Monthly energy review, June 1993

    Energy Technology Data Exchange (ETDEWEB)

    1993-06-25

    The Monthly Energy Review provides an overview of the production, distribution, and consumption of energy derived from petroleum, natural gas, coal, electricity, and nuclear energy. It also discusses oil and gas resource development, energy prices, and issues relevant to international energy markets.

  4. Monthly energy review, March 1994

    Energy Technology Data Exchange (ETDEWEB)

    1994-03-29

    The Monthly Energy Review provides information on production, distribution, consumption, prices, imports, and exports for the following US energy sources: petroleum; petroleum products; natural gas; coal; electricity; and nuclear energy. The section on international energy contains data for world crude oil production and consumption, petroleum stocks in OECD countries, and nuclear electricity gross generation.

  5. Monthly energy review, October 1993

    Energy Technology Data Exchange (ETDEWEB)

    1993-10-26

    The Monthly Energy Review gives information on production, distribution, and consumption for various energy sources, e.g. petroleum, natural gas, oil, coal, electricity, and nuclear energy. Some data is also included on international energy sources and supplies, the import of petroleum products into the US and pricing and reserves data (as applicable) for the various sources of energy listed above.

  6. Monthly energy review, December 1993

    Energy Technology Data Exchange (ETDEWEB)

    1993-12-22

    This document provides data on monthly energy use and fossil fuels. The following sections are included: Highlights: Emissions of greenhouse gases in the United States 1985--1990; Highlights: assessment of energy use in multibuilding facilities; energy overview; energy consumption; petroleum; natural gas; oil and gas resource development; coal; electricity; nuclear energy; energy prices; and international energy.

  7. Monthly energy review, April 1994

    Energy Technology Data Exchange (ETDEWEB)

    1994-04-01

    The Monthly Energy Review contains statistical data on the following: energy consumption, petroleum, natural gas, oil and gas resource development, coal, electricity, nuclear energy, energy prices, and international energy. In addition, an energy overview is provided, and, for the April issue, Energy use and carbon emissions; Some international comparisons.

  8. Monthly energy review, November 1995

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1995-11-01

    This document presents an overview of the Energy Information Administration`s recent monthly energy statistics. The statistics cover the major activities of US production, consumption, trade, stocks, and prices for petroleum, natural gas, coal, electricity, and nuclear energy. International energy and thermal and metric conversion factors are included.

  9. Monthly energy review, April 1997

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1997-04-01

    This report presents an overview of monthly energy statistics. The statistics cover the major activities of U.S. production, consumption, trade, stocks, and prices for petroleum, natural gas, coal, electricity, and nuclear energy. International energy and thermal metric conversion factors are included.

  10. Monthly energy review, December 1993

    International Nuclear Information System (INIS)

    1993-01-01

    This document provides data on monthly energy use and fossil fuels. The following sections are included: Highlights: Emissions of greenhouse gases in the United States 1985--1990; Highlights: assessment of energy use in multibuilding facilities; energy overview; energy consumption; petroleum; natural gas; oil and gas resource development; coal; electricity; nuclear energy; energy prices; and international energy

  11. Monthly energy review, December 1994

    International Nuclear Information System (INIS)

    1994-12-01

    This monthly publication contains statistical data on energy resources in the United States. Petroleum, natural gas, coal, electricity, and nuclear energy are covered. Additional sections include an energy overview, energy consumption, oil and gas resource development and energy prices. This issue includes a market assessment of alternative-fuel vehicles in the Atlanta private fleet for 1994

  12. Monthly energy review, April 1994

    International Nuclear Information System (INIS)

    1994-04-01

    The Monthly Energy Review contains statistical data on the following: energy consumption, petroleum, natural gas, oil and gas resource development, coal, electricity, nuclear energy, energy prices, and international energy. In addition, an energy overview is provided, and, for the April issue, Energy use and carbon emissions; Some international comparisons

  13. Natural gas monthly, December 1996

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-12-01

    This document highlights activities, events, and analysis of interest to the public and private sector associated with the natural gas industry. Volume and price data are presented each month for natural gas production, distribution, consumption, and interstate pipeline activities. Producer-related activities and underground storage data are also included.

  14. Prediction of Malaysian monthly GDP

    Science.gov (United States)

    Hin, Pooi Ah; Ching, Soo Huei; Yeing, Pan Wei

    2015-12-01

    The paper attempts to use a method based on multivariate power-normal distribution to predict the Malaysian Gross Domestic Product next month. Letting r(t) be the vector consisting of the month-t values on m selected macroeconomic variables, and GDP, we model the month-(t+1) GDP to be dependent on the present and l-1 past values r(t), r(t-1),…,r(t-l+1) via a conditional distribution which is derived from a [(m+1)l+1]-dimensional power-normal distribution. The 100(α/2)% and 100(1-α/2)% points of the conditional distribution may be used to form an out-of sample prediction interval. This interval together with the mean of the conditional distribution may be used to predict the month-(t+1) GDP. The mean absolute percentage error (MAPE), estimated coverage probability and average length of the prediction interval are used as the criterions for selecting the suitable lag value l-1 and the subset from a pool of 17 macroeconomic variables. It is found that the relatively better models would be those of which 2 ≤ l ≤ 3, and involving one or two of the macroeconomic variables given by Market Indicative Yield, Oil Prices, Exchange Rate and Import Trade.

  15. Monthly energy review, February 1990

    International Nuclear Information System (INIS)

    1990-01-01

    The Monthly Energy Review presents current data on production, consumption, stocks, imports, exports, and prices of the energy commodities in the United States. Also included are data on international production of crude oil, consumption of petroleum products, petroleum stocks, and production of electricity from nuclear-powered facilities

  16. Monthly energy review, July 1991

    International Nuclear Information System (INIS)

    1991-01-01

    The Monthly Energy Review presents current data on production, consumption, stocks, imports, exports, and prices of the principal energy commodities in the United States. Also included are data on international production of crude oil, consumption of petroleum products, petroleum stocks, and production of electricity from nuclear-powered facilities

  17. Monthly energy review, April 1991

    International Nuclear Information System (INIS)

    1991-01-01

    The Monthly Energy Review presents current data on production, consumption, stocks, imports, exports, and prices of the principal energy commodities in the United States. Also included are data on international production of crude oil, consumption of petroleum products, petroleum stocks, and production of electricity from nuclear-powered facilities

  18. Infrastructures of progress and dispossession

    DEFF Research Database (Denmark)

    Andersen, Astrid Oberborbeck

    2016-01-01

    and organizational infrastructural arrangements, it is argued, can open up for understanding how local and beyond-local processes tangle in complex ways and are productive of new subjectivities; how relations are reconfi gured in neoliberal landscapes of progress and dispossession. Such an approach makes evident how...... to reposition small and medium-scale farmers as backward. Th is article analyzes how farmers struggle to fi nd their place within a neoliberal urban ecology where diff erent conceptions of what constitutes progress in contemporary Peru infl uence the landscape. Using an analytical lens that takes material...... and organizational infrastructures and practices into account, and situates these in specifi c historical processes, the article argues that farmers within the urban landscape of Arequipa struggle to reclaim land and water, and reassert a status that they experience to be losing. Such a historical focus on material...

  19. Electric power monthly, July 1994

    Energy Technology Data Exchange (ETDEWEB)

    1994-07-01

    The Electric Power Monthly (EPM) presents monthly electricity statistics. The purpose of this publication is to provide energy decisionmakers with accurate and timely information that may be used in forming various perspectives on electric issues that lie ahead. Data in this report are presented for a wide audience including Congress, Federal and State agencies, the electric utility industry, and the general public. The EIA collected the information in this report to fulfill its data collection and dissemination responsibilities as specified in the Federal Energy Administration Act of 1974 (Public Law 93-275) as amended. The EPM is prepared by the Survey Management Division; Office of Coal, Nuclear, Electric and Alternate Fuels, Energy Information Administration (EIA), Department of Energy. This publication provides monthly statistics at the US, Census division, and State levels for net generation, fossil fuel consumption and stocks, quantity and quality of fossil fuels, cost of fossil fuels, electricity sales, revenue, and average revenue per kilowatthour of electricity sold. Data on net generation, fuel consumption, fuel stocks, quantity and cost of fossil fuels are also displayed for the North American Electric Reliability Council (NERC) regions. Statistics by company and plant are published in the EPM on the capability of new generating units, net generation, fuel consumption, fuel stocks, quantity and quality of fuel, and cost of fossil fuels. Data on quantity, quality, and cost of fossil fuels lag data on net generation, fuel consumption, fuel stocks, electricity sales, and average revenue per kilowatthour by 1 month. This difference in reporting appears in the US, Census division, and State level tables. However, for purposes of comparison, plant-level data are presented for the earlier month.

  20. Petroleum supply monthly, March 1994

    Energy Technology Data Exchange (ETDEWEB)

    1994-03-30

    Data presented in the Petroleum Supply Monthly (PSM) describe the supply and disposition of petroleum products in the United States and major US geographic regions. The data series describe production, imports and exports, inter-Petroleum Administration for Defense (PAD) District movements, and inventories by the primary suppliers of petroleum products in the United States (50 States and the District of Columbia). The reporting universe includes those petroleum sectors in primary supply. Included are: petroleum refiners, motor gasoline blenders, operators of natural gas processing plants and fractionators, inter-PAD transporters, importers, and major inventory holders of petroleum products and crude oil. When aggregated, the data reported by these sectors approximately represent the consumption of petroleum products in the United States. Data presented in the PSM are divided into two sections: Summary Statistics and Detailed Statistics. The tables and figures in the Summary Statistics section of the PSM present a time series of selected petroleum data on a US level. Most time series include preliminary estimates for one month based on the Weekly Petroleum Supply Reporting System; statistics based on the most recent data from the Monthly Petroleum Supply Reporting System (MPSRS); and statistics published in prior issues of the PSM and PSA. The Detailed Statistics tables of the PSM present statistics for the most current month available as well as year-to-date. In most cases, the statistics are presented for several geographic areas -- the United States (50 States and the District of Columbia), five PAD Districts, and 12 Refining Districts. At the US and PAD District level, the total volume and the daily rate of activities are presented. The statistics are developed from monthly survey forms submitted by respondents to the EIA and from data provided from other sources.

  1. ARM Climate Research Facility Monthly Instrument Report August 2010

    Energy Technology Data Exchange (ETDEWEB)

    Voyles, JW

    2010-09-28

    The purpose of this report is to provide a concise but comprehensive overview of Atmospheric Radiation Measurement Climate Research Facility instrumentation status. The report is divided into the following five sections: (1) new instrumentation in the process of being acquired and deployed, (2) field campaigns, (3) existing instrumentation and progress on improvements or upgrades, (4) proposed future instrumentation, and (5) Small Business Innovation Research instrument development.

  2. ARM Climate Research Facility Monthly Instrument Report September 2010

    Energy Technology Data Exchange (ETDEWEB)

    Voyles, JW

    2010-10-18

    The purpose of this report is to provide a concise but comprehensive overview of Atmospheric Radiation Measurement Climate Research Facility instrumentation status. The report is divided into the following five sections: (1) new instrumentation in the process of being acquired and deployed, (2) field campaigns, (3) existing instrumentation and progress on improvements or upgrades, (4) proposed future instrumentation, and (5) Small Business Innovation Research instrument development.

  3. ARM Climate Research Facility Monthly Instrument Report May 2010

    Energy Technology Data Exchange (ETDEWEB)

    Voyles, JW

    2010-06-21

    The purpose of this report is to provide a concise but comprehensive overview of Atmospheric Radiation Measurement Climate Research Facility instrumentation status. The report is divided into the following five sections: (1) new instrumentation in the process of being acquired and deployed, (2) field campaigns, (3) existing instrumentation and progress on improvements or upgrades, (4) proposed future instrumentation, and (5) Small Business Innovation Research instrument development.

  4. ARM Climate Research Facility Monthly Instrument Report June 2010

    Energy Technology Data Exchange (ETDEWEB)

    Voyles, JW

    2010-07-13

    The purpose of this report is to provide a concise but comprehensive overview of Atmospheric Radiation Measurement Climate Research Facility instrumentation status. The report is divided into the following five sections: (1) new instrumentation in the process of being acquired and deployed, (2) field campaigns, (3) existing instrumentation and progress on improvements or upgrades, (4) proposed future instrumentation, and (5) Small Business Innovation Research instrument development.

  5. ARM Climate Research Facility Monthly Instrument Report July 2010

    Energy Technology Data Exchange (ETDEWEB)

    Voyles, JW

    2010-08-18

    The purpose of this report is to provide a concise but comprehensive overview of Atmospheric Radiation Measurement Climate Research Facility instrumentation status. The report is divided into the following five sections: (1) new instrumentation in the process of being acquired and deployed, (2) field campaigns, (3) existing instrumentation and progress on improvements or upgrades, (4) proposed future instrumentation, and (5) Small Business Innovation Research instrument development.

  6. Compliance status

    International Nuclear Information System (INIS)

    Black, D.G.

    1995-01-01

    This section of the 1994 Hanford Site Environmental Report summarizes the activities conducted to ensure that the Hanford Site is in compliance with federal environmental protection statutes and related Washington State and local environmental protection regulations and the status of Hanford's compliance with these requirements. Environmental permits required under the environmental protection regulations are discussed under the applicable statute

  7. Compliance status

    Energy Technology Data Exchange (ETDEWEB)

    Black, D.G.

    1995-06-01

    This section of the 1994 Hanford Site Environmental Report summarizes the activities conducted to ensure that the Hanford Site is in compliance with federal environmental protection statutes and related Washington State and local environmental protection regulations and the status of Hanford`s compliance with these requirements. Environmental permits required under the environmental protection regulations are discussed under the applicable statute.

  8. STATUS REPORT

    Indian Academy of Sciences (India)

    First page Back Continue Last page Graphics. STATUS REPORT. Raman scattering observed – 90, 135, 180 degrees and back scattering. Traditionally specific angle dependence to learn about polarization response. Learn molecular information from the surface or materials just below the surface (upto 12 mm depth) ...

  9. Progress of the HTR-10 project

    International Nuclear Information System (INIS)

    Zhong, D.; Xu, Y.

    1996-01-01

    This paper briefly introduces the main technical features and the design specifications of the HTR-10. Present status and main progress of the license applications, the design and manufacture of the main components and the engineering experiments as well as the construction of the HTR-10 are summarized. (author). 3 tabs

  10. The BGO collaboration progress report 1990

    International Nuclear Information System (INIS)

    Anon.

    1990-01-01

    A large solid angle BGO calorimeter is under contruction for photo-nuclear experiments at intermediate energy facilities. In this note the status progress of the project, the technical steps undertaken in the construction of the apparatus and the goals of this initiative are reviewed

  11. Beyond metric gravity: Progress on PS-200

    International Nuclear Information System (INIS)

    Goldman, T.; Brown, R.E.; Camp, J.B.; Darling, T.; Dyer, P.; Holzscheiter, M.H.; Hughes, R.J.; Jarmie, N.; King, N.S.P.; Lizon, D.C.; Nieto, M.M.; Schauer, M.M.M.; Schecker, J.A.; Cornford, S.; Hosea, K.; Kenefick, R.A.; Hoibraaten, S.; Midzor, M.M.; Parry, S.P.; Ristenen, R.A.; Witteborn, F.C.

    1993-01-01

    The reconciliation of quantum mechanics and gravity on varying distance scales requires changes to General Relativity that may be testable implications. We briefly review the status of tests with matter of the inverse square law and the principle of equivalence, then report on progress on the drift-tube measurement section of PS- 200, the experiment to measure the gravitational acceleration of antiprotons

  12. MD1003 (high-dose biotin) for the treatment of progressive multiple sclerosis: A randomised, double-blind, placebo-controlled study.

    Science.gov (United States)

    Tourbah, Ayman; Lebrun-Frenay, Christine; Edan, Gilles; Clanet, Michel; Papeix, Caroline; Vukusic, Sandra; De Sèze, Jerome; Debouverie, Marc; Gout, Olivier; Clavelou, Pierre; Defer, Gilles; Laplaud, David-Axel; Moreau, Thibault; Labauge, Pierre; Brochet, Bruno; Sedel, Frédéric; Pelletier, Jean

    2016-11-01

    Treatment with MD1003 (high-dose biotin) showed promising results in progressive multiple sclerosis (MS) in a pilot open-label study. To confirm the efficacy and safety of MD1003 in progressive MS in a double-blind, placebo-controlled study. Patients (n = 154) with a baseline Expanded Disability Status Scale (EDSS) score of 4.5-7 and evidence of disease worsening within the previous 2 years were randomised to 12-month MD1003 (100 mg biotin) or placebo thrice daily, followed by 12-month MD1003 for all patients. The primary endpoint was the proportion of patients with disability reversal at month 9, confirmed at month 12, defined as an EDSS decrease of ⩾1 point (⩾0.5 for EDSS 6-7) or a ⩾20% decrease in timed 25-foot walk time compared with the best baseline among screening or randomisation visits. A total of 13 (12.6%) MD1003-treated patients achieved the primary endpoint versus none of the placebo-treated patients (p = 0.005). MD1003 treatment also reduced EDSS progression and improved clinical impression of change compared with placebo. Efficacy was maintained over follow-up, and the safety profile of MD1003 was similar to that of placebo. MD1003 achieves sustained reversal of MS-related disability in a subset of patients with progressive MS and is well tolerated. © The Author(s), 2016.

  13. Petroleum marketing monthly, August 1994

    Energy Technology Data Exchange (ETDEWEB)

    1994-08-15

    The Petroleum Marketing Monthly (PMM) provides information and statistical data on a variety of crude oils and refined petroleum products. The publication presents statistics on crude oil costs and refined petroleum products sales for use by industry, government, private sector analysts, educational institutions, and consumers. Data on crude oil include the domestic first purchase price, the f.o.b. and landed cost of imported crude oil, and the refiners` acquisition cost of crude oil. Refined petroleum product Sales data include motor gasoline, distillates, residuals, aviation fuels, kerosene, and propane. The Petroleum Marketing Division, Office of Oil and Gas, Energy Information Administration ensures the accuracy, quality, and confidentiality of the published data in the Petroleum Marketing Monthly.

  14. Petroleum marketing monthly, June 1994

    Energy Technology Data Exchange (ETDEWEB)

    1994-06-01

    The Petroleum Marketing Monthly (PMM) provides information and statistical data on a variety of crude oils and refined petroleum products. The publication presents statistics on crude oil costs and refined petroleum products sales for use by industry, government, private sector analysts, educational institutions, and consumers. Data on crude oil include the domestic first purchase price, the f.o.b. and landed cost of imported crude oil, and the refiners` acquisition cost of crude oil. Refined petroleum product sales data include motor gasoline, distillates, residuals, aviation fuels, kerosene, and propane. Monthly statistics on purchases of crude oil and sales of petroleum products are presented in five sections: Summary Statistics; Crude Oil Prices; Prices of Petroleum Products; Volumes of Petroleum Products; and Prime Supplier Sales Volumes of Petroleum Products for Local Consumption. The feature article is entitled ``The Second Oxygenated Gasoline Season.`` 7 figs., 50 tabs.

  15. Petroleum marketing monthly, September 1994

    Energy Technology Data Exchange (ETDEWEB)

    1994-09-01

    The Petroleum Marketing Monthly (PMM) provides information and statistical data on a variety of crude oils and refined petroleum products. The publication presents statistics on crude oil costs and refined petroleum product sales for use by industry, government, private sector analysts, educational institutions, and consumers. Data on crude oil include the domestic first purchase price, the f.o.b. and landed cost of imported crude oil, and the refiners` acquisition cost of crude oil. Refined petroleum product sales data include motor gasoline, distillates, residuals, aviation fuels, kerosene, and propane. The Petroleum Marketing Division, Office of Oil and Gas, Energy Information Administration ensures the accuracy, quality, and confidentiality of the published data in the Petroleum Marketing Monthly.

  16. Petroleum marketing monthly, July 1994

    Energy Technology Data Exchange (ETDEWEB)

    1994-07-01

    The Petroleum Marketing Monthly (PMM) provides information and statistical data on a variety of crude oils and refined petroleum products. The publication presents statistics on crude oil costs and refined petroleum products sales for use by industry, government, private sector analysts, educational institutions, and consumers. Data on crude oil include the domestic first purchase price, the f.o.b. and landed cost of imported crude oil, and the refiners` acquisition cost of crude oil. Refined petroleum product sales data include motor gasoline, distillates, residuals, aviation fuels, kerosene, and propane. Monthly statistics on purchases of crude oil and sales of petroleum products are presented in five sections: summary statistics; crude oil prices; prices of petroleum products; volumes of petroleum products; and prime supplier sales volumes of petroleum products for local consumption. 7 figs., 50 tabs.

  17. Monthly energy review, March 1998

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1998-03-01

    The Monthly Energy Review (MER) presents an overview of the Energy Information Administration`s recent monthly energy statistics. The statistics cover the major activities of U.S. production, consumption, trade, stocks, and prices for petroleum, natural gas, coal, electricity, and nuclear energy. Also included are international energy and thermal and metric conversion factors. Energy production during December 1997 totaled 5.9 quadrillion Btu, a 2.8 percent increase from the level of production during December 1996. Coal production increased 9.5 percent, natural gas production increased 3.9 percent, and production of crude oil and natural gas plant liquids decreased 1.1 percent. All other forms of energy production combined were down 6.9 percent from the level of production during December 1996.

  18. Electric power monthly, April 1991

    International Nuclear Information System (INIS)

    1991-01-01

    The Electric Power Monthly (EPM) presents monthly summaries of electric utility statistics at the national Census division, and State level. The purpose of this publication is to provide energy decision makers with accurate and timely information that may be used in forming various perspectives on electric issues that lie ahead. Data are given for net generation, fuel consumption, fuel stocks, quantity and quality of fuel, cost of fuel, electricity sales, revenue, and average revenue per kilowatt hour of electricity sold. Data on net generation are also displayed at the North American Electric Reliability Council (NERC) region level. Additionally, statistics at the company and plant level are published in the EPM on capability of new plants, net generation, fuel consumption, fuel stocks, quantity and quality of fuel, and cost of fuel. 6 figs., 57 tabs

  19. Natural gas monthly, February 1994

    Energy Technology Data Exchange (ETDEWEB)

    1994-02-25

    The NGM highlights activities, events, and analyses of interest to public and private sector organizations associated with the natural gas industry. Volume and price data are presented each month for natural gas production, distribution, consumption, and interstate pipeline activities. Producer-related activities and underground storage data are also reported. The NGM also features articles designed to assist readers in using and interpreting natural gas information.

  20. Electric Power monthly, November 1996

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-11-01

    This publication presents monthly electricity statistics for a wide audience including Congress, Federal and state agencies, the electric utility industry, and the general public. Purpose is to provide energy decisionmakers with accurate and timely information that may be used in forming various perspectives on electric issues that lie ahead. EIA collected the information in this report to fulfill its data collection and dissemination responsibilities as specified in the Federal Energy Administration Act of 1974 (Public Law 93-275) as amended.