One-year post-primary antibody persistence and booster immune ...

African Journals Online (AJOL)

One-year post-primary antibody persistence and booster immune response to a DTaP-IPV//PRP~T vaccine (Pentaxim) given at 18 - 19 months of age in South African children primed at 6, 10 and 14 weeks of age with the same vaccine.

Operational behaviour of CO{sub 2} booster systems; Betriebsverhalten von CO{sub 2}-Booster-Systemen

Energy Technology Data Exchange (ETDEWEB)

Javerschek, Oliver; Hieble, Tobias [BITZER Kuehlmaschinenbau GmbH, Sindelfingen (Germany)

2011-07-01

The operating characteristics of booster systems and the resulting operating conditions of CO{sub 2} booster systems in supermarket refrigeration are explained and discussed. Criteria and challenges of different operating and load conditions are gone into. Simulated and measured operating states of a small-scale booster system are compared and evaluated. [German] In der vorliegenden Veroeffentlichung werden unterschiedliche Betriebsverhalten und die daraus resultierenden Betriebsbedingungen von CO{sub 2}-Booster-Systemen in der Supermarktkaelte erlaeutert und diskutiert. Dabei werden wesentliche Kriterien und Herausforderungen bei den unterschiedlichen Betriebs- und Lastbedingungen besprochen. Ausserdem werden simulierte und gemessene Betriebszustaende einer kleinen Booster-Kaelteanlage vergleichend betrachtet und bewertet.

BROOKHAVEN: Booster commissioned

Energy Technology Data Exchange (ETDEWEB)

Bleser, Ed

1992-03-15

The construction and first commissioning phase of the Booster synchrotron to inject into Brookhaven's veteran Alternating Gradient Synchrotron (AGS) were completed last year. Scheduled to come into operation this year, the new Booster will extend the research capabilities AGS, and with its ability to accelerate partially stripped heavy ions will play an essential role in the chain of accelerators serving the Relativistic Heavy Ion Collider (RHIC)

Pressure-Equalizing Cradle for Booster Rocket Mounting

Science.gov (United States)

Rutan, Elbert L. (Inventor)

2015-01-01

A launch system and method improve the launch efficiency of a booster rocket and payload. A launch aircraft atop which the booster rocket is mounted in a cradle, is flown or towed to an elevation at which the booster rocket is released. The cradle provides for reduced structural requirements for the booster rocket by including a compressible layer, that may be provided by a plurality of gas or liquid-filled flexible chambers. The compressible layer contacts the booster rocket along most of the length of the booster rocket to distribute applied pressure, nearly eliminating bending loads. Distributing the pressure eliminates point loading conditions and bending moments that would otherwise be generated in the booster rocket structure during carrying. The chambers may be balloons distributed in rows and columns within the cradle or cylindrical chambers extending along a length of the cradle. The cradle may include a manifold communicating gas between chambers.

PS Booster - Festive colloquium

CERN Multimedia

2012-01-01

A festive colloquium will be held to celebrate the 40th anniversary of the PS Booster on Friday, 28 September at 2 p.m. in the CERN council chamber. The meeting will be open to everybody. Read more on the PS Booster in the CERN Bulletin and in the CERN Courier.

AGS booster prototype magnets

International Nuclear Information System (INIS)

Danby, G.; Jackson, J.; Lee, Y.Y.; Phillips, R.; Brodowski, J.; Jablonski, E.; Keohane, G.; McDowell, B.; Rodger, E.

1987-01-01

Prototype magnets have been designed and constructed for two half cells of the AGS Booster. The lattice requires 2.4m long dipoles, each curved by 10 0 . The multi-use Booster injector requires several very different standard magnet cycles, capable of instantaneous interchange using computer control from dc up to 10 Hz

AGS Booster prototype magnets

Energy Technology Data Exchange (ETDEWEB)

Danby, G.; Jackson, J.; Lee, Y.Y.; Phillips, R.; Brodowski, J.; Jablonski, E.; Keohane, G.; McDowell, B.; Rodger, E.

1987-03-19

Prototype magnets have been designed and constructed for two half cells of the AGS Booster. The lattice requires 2.4m long dipoles, each curved by 10/sup 0/. The multi-use Booster injector requires several very different standard magnet cycles, capable of instantaneous interchange using computer control from dc up to 10 Hz.

Immunity booster

International Nuclear Information System (INIS)

Stefanescu, Ioan; Titescu, Gheorghe; Tamaian, Radu; Haulica, Ion; Bild, Walther

2002-01-01

The immunity booster is, according to its patent description, microbiologically pure water with an D/(D+H) isotopic concentration of 100 ppm, with physical-chemical characteristics similar to those of distilled water. It is obtained by sterilization of a mixture of deuterium depleted water, with a 25 ppm isotopic concentration, with distilled water in a volume ratio of 4:6. Unlike natural immunity boosters (bacterial agents as Bacillus Chalmette-Guerin, Corynebacterium parvum; lipopolysaccharides; human immunoglobulin) or synthetical products (levamysol; isoprinosyne with immunostimulating action), which cause hypersensitivity and shocks, thrill, fever, sickness and the immunity complex disease, the water of 100 ppm D/(D + H) isotopic concentration is a toxicity free product. The testing for immune reaction of the immunity booster led to the following results: - an increase of cell action capacity in the first immunity shielding stage (macrophages), as evidenced by stimulation of a number of essential characterizing parameters, as well as of the phagocytosis capacity, bactericide capacity, and opsonic capacity of serum; - an increase of the number of leucocyte particularly of the granulocyte in peripheral blood, produced especially when medullar toxic agents like caryolysine are used; - it hinders the effect of lowering the number of erythrocytes in peripheral blood produced by experimentally induced chronic inflammation; - an increase of nonspecific immunity defence capacity against specific bacterial aggression of both Gram-positive bacteria (Streptococcus pneumoniae 558 ) and of the Gram-negative ones (Klebsiella pneumoniae 507 ); - an increase of immunity - stimulating activity (proinflamatory), like that of levamisole as evidenced by the test of stimulation of experimentally induced inflammation by means of carrageenan. The following advantages of the immunity booster are stressed: - it is toxicity free and side effect free; - can be orally administrated as

47 CFR 74.733 - UHF translator signal boosters.

Science.gov (United States)

2010-10-01

... 47 Telecommunication 4 2010-10-01 2010-10-01 false UHF translator signal boosters. 74.733 Section... Translator, and TV Booster Stations § 74.733 UHF translator signal boosters. (a) The licensee of a UHF television broadcast translator station may be authorized to operate one or more signal boosters for the...

Magnetic field errors tolerances of Nuclotron booster

Science.gov (United States)

Butenko, Andrey; Kazinova, Olha; Kostromin, Sergey; Mikhaylov, Vladimir; Tuzikov, Alexey; Khodzhibagiyan, Hamlet

2018-04-01

Generation of magnetic field in units of booster synchrotron for the NICA project is one of the most important conditions for getting the required parameters and qualitative accelerator operation. Research of linear and nonlinear dynamics of ion beam 197Au31+ in the booster have carried out with MADX program. Analytical estimation of magnetic field errors tolerance and numerical computation of dynamic aperture of booster DFO-magnetic lattice are presented. Closed orbit distortion with random errors of magnetic fields and errors in layout of booster units was evaluated.

The PS Booster hits 40

CERN Multimedia

Joannah Caborn Wengler

2012-01-01

Many accelerators’ "round" birthdays are being celebrated at CERN these days – the PS turned 50 in 2009, the SPS was 35 in 2011, and this year it's the turn of the PS Booster to mark its 40th anniversary. Originally designed to accelerate 1013 protons to 800 MeV, it has far exceeded its initial design performance over the years.   The PS Booster in the 1970s. Imagine the scene: a group of accelerator physicists staring expectantly at a monitor, when suddenly a shout of joy goes up as a signal flickers across the screen. Does that sound familiar? Well, turn the clock back 40 years (longer hair, wider trouser legs) and you have the situation at the PS Booster on 26 May 1972. On that day, beam was injected into the Booster for the first time. “It was a real buzz,” says Heribert Koziol, then Chairman of the Running-in Committee. “We were very happy – and also a little relieved – when the beam finally...

Cabling design of booster and storage ring construction progress of TPS

International Nuclear Information System (INIS)

Wong, Y.-S.; Liu, K.-B.; Liu, C.-Y.; Wang, B.-S.

2017-01-01

The 2012 Taiwan Photon Source (TPS) cable construction project started after 10 months to complete the cable laying and installation of power supply. The circumference of the booster ring (BR) is 496.8 m, whereas that of the storage ring (SR) is 518.4 m. Beam current is set to 500 mA at 3.3 GeV. The paper on grounding systems discusses the design of the ground wire (< 0.2 Ω) with low impedance, power supply of the accelerator and cabling tray. The flow and size of the ground current are carefully evaluated to avoid grounded current from flowing everywhere, which causes interference problems. In the design of the TPS, special shielding will be established to isolate the effects of electromagnetic interference on the magnet and ground current. Booster ring dipoles are connected by a series of 54-magnet bending dipole; the cable size of its stranded wire measures 250 mm"2, with a total length of 5000 m. Booster ring and storage ring quadrupoles have 150 magnets; the cable size of their stranded wire is 250 mm"2, with a total length of 17000 m. Storage ring dipole consists of 48 magnets; the cable size of its stranded wire is 325 mm"2, with a total length of 6000 m. This study discusses the power supply cabling design of the storage ring and booster ring construction progress of TPS. The sections of this paper are divided into discussions of the construction of the control and instrument area, cabling layout of booster ring and storage ring, as well as the installation and commission machine. This study also discusses the use of a high-impedance meter to determine the effect of cabling insulation and TPS power supply machine on energy transfer to ensure the use of safe and correct magnet.

Persistence of bactericidal antibodies following early infant vaccination with a serogroup B meningococcal vaccine and immunogenicity of a preschool booster dose.

Science.gov (United States)

Snape, Matthew D; Saroey, Praveen; John, Tessa M; Robinson, Hannah; Kelly, Sarah; Gossger, Nicoletta; Yu, Ly-Mee; Wang, Huajun; Toneatto, Daniela; Dull, Peter M; Pollard, Andrew J

2013-10-15

The multicomponent serogroup B meningococcal (4CMenB) vaccine was recently licensed for use in Europe. There are currently no data on the persistence of bactericidal antibodies induced by use of this vaccine in infants. Our objective was to evaluate serogroup B-specific bactericidal antibodies in children aged 40-44 months previously vaccinated at 2, 4, 6 and 12 months of age. Participants given 4 doses of 4CMenB as infants received a fifth dose of the vaccine at 40-44 months of age. Age-matched participants who were MenB vaccine-naive received 4CMenB and formed the control group. We evaluated human complement serum bactericidal activity (hSBA) titres at baseline and 1 month after each dose of 4CMenB. Before a booster dose at enrolment, 41%-76% of 17 participants previously vaccinated with 4CMenB in infancy had hSBA titres of 4 or greater against 4 reference strains. Before vaccination in the control group (n = 40) these proportions were similar for strains 44/76-SL (63%) and M10713 (68%) but low for strains NZ98/254 (0%) and 5/99 (3%). A booster dose in the 4CMenB-primed participants generated greater increases in hSBA titres than in controls. As has been observed with other meningococcal vaccines, bactericidal antibodies waned after vaccination with 4CMenB administered according to an approved infant vaccination schedule of 2, 4, 6 and 12 months of age, but there was an anamnestic response to a booster dose at 40-44 months of age. If 4CMenB were introduced into routine vaccination schedules, assessment of the need for a booster dose would require data on the impact of these declining titres on vaccine effectiveness. ClinicalTrials.gov, no. NCT01027351.

Fox-7 for Insensitive Boosters

Science.gov (United States)

2010-08-01

cavitation , and therefore nucleation, to occur at each frequency. As well as producing ultrasound at different frequencies, the method of delivery of...processing techniques using ultrasound , designed to optimise FOX-7 crystal size and morphology to improve booster formulations, and results from these...7 booster formulations. Also included are particle processing techniques using ultrasound , designed to optimise FOX-7 crystal size and morphology

The Booster

CERN Multimedia

1972-01-01

Where the beams from the Booster's four rings begin to recombine, before transfer to the PS. On the left are dipoles for vertical steering, and on the right is the tank containing two septum magnets which form the first combining element.

RF cogging in the FNAL Booster Accelerator

International Nuclear Information System (INIS)

William A. Pellico and Robert C. Webber

2000-01-01

The Fermilab Booster operates at a Radio Frequency (RF) harmonic number of 84 with beam in all buckets. One or two bunches of beam are systematically lost in the 8 GeV extraction process as beam is swept across a magnetic septum during the extraction kicker rise time. The prompt radiation and component activation resulting from this localized high energy beam loss become serious concerns as Booster beam throughput must be increased more than tenfold to meet the requirements of RUN II, NUMI, and MiniBooNE experiments. Synchronizing a gap in the beam to the firing of the extraction kickers, a relatively easy and standard practice in many machines, can eliminate the problem. This seemingly simple operation is greatly complicated in the Booster by the need to synchronize extraction to beam already circulating in the Main Injector. Coupled with the inflexibility of the Booster resonant magnetic cycle, cycle to cycle variations, and constraints inherent in the accelerator physics, that requirement forces active control of the gap's azimuthal position throughout the acceleration process as the revolution frequency sweeps rapidly. Until recently, the complexities of actually implementing and demonstrating this process in the Booster had not been worked out. This paper describes a successful demonstration of gap cogging in the Booster

Summary of Booster Development and Qualification Report

Energy Technology Data Exchange (ETDEWEB)

Francois, Elizabeth G. [Los Alamos National Laboratory; Harry, Herbert H. [Los Alamos National Laboratory; Hartline, Ernest L. [Los Alamos National Laboratory; Hooks, Daniel E. [Los Alamos National Laboratory; Johnson, Carl E. [Los Alamos National Laboratory; Morris, John S. [Los Alamos National Laboratory; Novak, Alan M. [Los Alamos National Laboratory; Ramos, Kyle J. [Los Alamos National Laboratory; Sanders, Victor E. [Los Alamos National Laboratory; Scovel, Christina A. [Los Alamos National Laboratory; Lorenz, Thomas [LLNL; Wright, Mark [AWE; Botcher, Tod [PANTEX; Marx, Erin [NSWC-IHDIV; Gibson, Kevin [NSWC-IHDIV

2012-06-21

This report outlines booster development work done at Los Alamos National Laboratory from 2007 to present. The booster is a critical link in the initiation train of explosive assemblies, from complex devices like nuclear weapons to conventional munitions. The booster bridges the gap from a small, relatively sensitive detonator to an insensitive, but massive, main charge. The movement throughout the explosives development community is to use more and more insensitive explosive components. With that, more energy is needed out of the booster. It has to initiate reliably, promptly, powerfully and safely. This report is divided into four sections. The first provides a summary of a collaborative effort between LANL, LLNL, and AWE to identify candidate materials and uniformly develop a testing plan for new boosters. Important parameters and the tests required to measure them were defined. The nature of the collaboration and the specific goals of the participating partners has changed over time, but the booster development plan stands on its own merit as a complete description of the test protocol necessary to compare and qualify booster materials, and is discussed in its entirety in this report. The second section describes a project, which began in 2009 with the Department of Defense to develop replacement booster formulations for PBXN-7. Replacement of PBXN-7 was necessary because it contained Triaminotrinitrobenzene (TATB), which was becoming unavailable to the DoD and because it contained Cyclotrimethylenetrinitramine (RDX), which was sensitive and toxic. A LANL-developed explosive, Diaminoazoxyfurazan (DAAF), was an important candidate. This project required any replacement formulation be a drop-in replacement in existing munitions. This project was timely, in that it made use of the collaborative booster development project, and had the additional constraint of matching shock sensitivity. Additionally it needed to be a safety improvement, and a performance

30 CFR 57.8518 - Main and booster fans.

Science.gov (United States)

2010-07-01

... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Main and booster fans. 57.8518 Section 57.8518... and Underground § 57.8518 Main and booster fans. (a) All mine main and booster fans installed and used...-cycle shutdowns or planned or scheduled fan maintenance or fan adjustments where air quality is...

Improvement of seawater booster pump outlet check valve

International Nuclear Information System (INIS)

Li Xuning; Du Yansong; Huang Huimin

2010-01-01

Conventional island seawater booster pump set of QNPC 310 MWe unit are very important in the whole circulating cooling system, and the integrate function of seawater booster pump outlet check valve is the foundation of steady operation of the seawater booster pump set. The article mainly introduce that through the analyses to the reason to the problem that the seawater booster pump outlet check valve of QNPC 310 MWe unit appeared in past years by our team, and considering the influence of operation condition and circumstance, the team improve the seawater booster pump outlet check valve from swing check valve to shuttle check valve which operate more appropriately in the system. By the test of continuous practice, we make further modification to the inner structure of shuttle check valve contrapuntally, and therefore we solve the problem in seawater booster pump outlet check valve fundamentally which has troubled the security of system operation in past years, so we realize the aim of technical improvement and ensure that the system operate in safety and stability. (authors)

Conceptual design report: superconducting booster

International Nuclear Information System (INIS)

1983-01-01

The Superconducting Booster project includes the construction of a new high-voltage injector and buncher for the existing tandem, a magnetic transport system, an rf linac with superconducting resonators, and a rebuncher-debuncher. The booster will fit in existing space so that a new building is not required. The layout of the accelerator is given in Fig. I-1. The University of Washington is contributing approximately $1 M to this project

Thermodynamic investigation of a booster-assisted ejector refrigeration system

International Nuclear Information System (INIS)

Zhao, Hongxia; Zhang, Ke; Wang, Lei; Han, Jitian

2016-01-01

Highlights: • COP based on thermal input increases with booster outlet pressure. • Both entrainment ratio and area ratio increase with booster outlet pressure. • COP based on work is larger than compressor-based refrigeration system. • An optimum booster outlet pressure obtains maximum COP based on work. • Exergy destruction occurs mainly in ejector, condenser, evaporator and generator. - Abstract: In order to improve performance of ejector refrigeration system, a booster is added before an ejector to enhance secondary flow pressure, which is called a booster assisted refrigeration system. Based on mass, momentum and energy conservation, a 1D model of ejector for optimal performance prediction was presented and validated with experimental data. A detailed study of working characteristics of the booster assisted ejector refrigeration system was carried out and compared against conventional ejector refrigeration system and compressor based refrigeration system, on the basis of first and second laws of thermodynamics. Effects of booster outlet pressure on COP_t_h based on thermal energy and COP_w based on work input, and also on entrainment ratio and area ratio of ejector were studied. The exergy destruction rates were also computed and analyzed for components of the booster-assisted ejector refrigeration system. Ways to reduce exergy destruction were discussed.

Gas Test Loop Booster Fuel Hydraulic Testing

International Nuclear Information System (INIS)

Gas Test Loop Hydraulic Testing Staff

2006-01-01

The Gas Test Loop (GTL) project is for the design of an adaptation to the Advanced Test Reactor (ATR) to create a fast-flux test space where fuels and materials for advanced reactor concepts can undergo irradiation testing. Incident to that design, it was found necessary to make use of special booster fuel to enhance the neutron flux in the reactor lobe in which the Gas Test Loop will be installed. Because the booster fuel is of a different composition and configuration from standard ATR fuel, it is necessary to qualify the booster fuel for use in the ATR. Part of that qualification is the determination that required thermal hydraulic criteria will be met under routine operation and under selected accident scenarios. The Hydraulic Testing task in the GTL project facilitates that determination by measuring flow coefficients (pressure drops) over various regions of the booster fuel over a range of primary coolant flow rates. A high-fidelity model of the NW lobe of the ATR with associated flow baffle, in-pile-tube, and below-core flow channels was designed, constructed and located in the Idaho State University Thermal Fluids Laboratory. A circulation loop was designed and constructed by the university to provide reactor-relevant water flow rates to the test system. Models of the four booster fuel elements required for GTL operation were fabricated from aluminum (no uranium or means of heating) and placed in the flow channel. One of these was instrumented with Pitot tubes to measure flow velocities in the channels between the three booster fuel plates and between the innermost and outermost plates and the side walls of the flow annulus. Flow coefficients in the range of 4 to 6.5 were determined from the measurements made for the upper and middle parts of the booster fuel elements. The flow coefficient for the lower end of the booster fuel and the sub-core flow channel was lower at 2.3

Gas Test Loop Booster Fuel Hydraulic Testing

Energy Technology Data Exchange (ETDEWEB)

Gas Test Loop Hydraulic Testing Staff

2006-09-01

The Gas Test Loop (GTL) project is for the design of an adaptation to the Advanced Test Reactor (ATR) to create a fast-flux test space where fuels and materials for advanced reactor concepts can undergo irradiation testing. Incident to that design, it was found necessary to make use of special booster fuel to enhance the neutron flux in the reactor lobe in which the Gas Test Loop will be installed. Because the booster fuel is of a different composition and configuration from standard ATR fuel, it is necessary to qualify the booster fuel for use in the ATR. Part of that qualification is the determination that required thermal hydraulic criteria will be met under routine operation and under selected accident scenarios. The Hydraulic Testing task in the GTL project facilitates that determination by measuring flow coefficients (pressure drops) over various regions of the booster fuel over a range of primary coolant flow rates. A high-fidelity model of the NW lobe of the ATR with associated flow baffle, in-pile-tube, and below-core flow channels was designed, constructed and located in the Idaho State University Thermal Fluids Laboratory. A circulation loop was designed and constructed by the university to provide reactor-relevant water flow rates to the test system. Models of the four booster fuel elements required for GTL operation were fabricated from aluminum (no uranium or means of heating) and placed in the flow channel. One of these was instrumented with Pitot tubes to measure flow velocities in the channels between the three booster fuel plates and between the innermost and outermost plates and the side walls of the flow annulus. Flow coefficients in the range of 4 to 6.5 were determined from the measurements made for the upper and middle parts of the booster fuel elements. The flow coefficient for the lower end of the booster fuel and the sub-core flow channel was lower at 2.3.

Design of the Zero Gradient Synchrotron Booster-II lattice

International Nuclear Information System (INIS)

Crosbie, E.A.; Foss, M.H.; Khoe, T.K.; Simpson, J.D.

1975-01-01

A 500 MeV booster was designed at the Argonne National Laboratory to increase the beam intensity from the Zero Gradient Synchrotron (ZGS). Many turns of H - ions from the 50 MeV linac will be injected into the booster and stripped to H + so that the ring will contain the maximum useful charge in each booster pulse. Several booster pulses will be injected into the ZGS to form one ZGS pulse. This machine is now under construction. (auth)

Booster gold beam injection efficiency and beam loss

International Nuclear Information System (INIS)

Zhang, S.Y.; Ahrens, L.A.

1998-01-01

The Relativistic Heavy Ion Collider (RHIC) at the BNL requires the AGS to provide Gold beam with the intensity of 10 9 ions per bunch. Over the years, the Tandem Van de Graaff has provided steadily increasing intensity of gold ion beams to the AGS Booster. However, the gold beam injection efficiency at the Booster has been found to decrease with the rising intensity of injected beams. As the result, for Tandem beams of the highest intensity, the Booster late intensity is lower than with slightly lower intensity Tandem beam. In this article, the authors present two experiments associated with the Booster injection efficiency and beam intensity. One experiment looks at the Booster injection efficiency by adjusting the Tandem beam intensity, and another looks at the beam life time while scraping the beam in the Booster. The studies suggest that the gold beam injection efficiency at the AGS Booster is related to the beam loss in the ring, rather than the intensity of injected beam or circulating beam. A close look at the effect of the lost gold ion at the Booster injection leads to the prediction that the lost gold ion creates large number of positive ions, and even larger number of electrons. The lost gold beam is also expected to create large numbers of neutral particles. In 1998 heavy ion run, the production of positive ions and electrons due to the lost gold beam has been observed. Also the high vacuum pressure due to the beam loss, presumably because of the neutral particles it created, has been measured. These results will be reported elsewhere

Compatibility of booster seats and vehicles in the U.S. market.

Science.gov (United States)

Bing, Julie A; Agnew, Amanda M; Bolte, John H

2018-05-19

The objective of this study was to analyze booster and rear vehicle seat dimensions to identify the most frequent compatibility problems. Measurements were collected from 40 high-back and backless boosters and 95 left rear and center rear row seating positions in 50 modern vehicles. Dimensions were compared for 3,800 booster/vehicle seat combinations. For validation and estimation of tolerance and correction factors, 72 booster installations were physically completed and compared with measurement-based compatibility predictions. Dimensions were also compared to the International Organization for Standardization (ISO) volumetric envelopes of forward-facing child restraints and boosters. Seat belt buckles in outboard positions accommodated the width of boosters better than center positions (success rates of 85.4 and 34.7%, respectively). Adequate head restraint clearance occurred in 71.9 to 77.2% of combinations, depending on the booster's head support setting. Booster recline angles aligned properly with vehicle seat cushion angles in 71.5% of combinations. In cases of poor angle alignment, booster angles were more obtuse than the vehicle seat angles 97.7% of the time. Head restraint interference exacerbated angle alignment issues. Data indicate success rates above 90% for boosters being fully supported by the length of the seat cushion and for adequate height clearance with the vehicle roofline. Comparison to ISO envelopes indicates that most boosters on the U.S. market are taller and angled more obtusely than ISO target envelopes. This study quantifies some of the common interferences between boosters and vehicles that may complicate booster usage. Data are useful for design and to prioritize specific problem areas.

Developing the World's Most Powerful Solid Booster

Science.gov (United States)

Priskos, Alex S.; Frame, Kyle L.

2016-01-01

NASA's Journey to Mars has begun. Indicative of that challenge, this will be a multi-decadal effort requiring the development of technology, operational capability, and experience. The first steps are underway with more than 15 years of continuous human operations aboard the International Space Station (ISS) and development of commercial cargo and crew transportation capabilities. NASA is making progress on the transportation required for deep space exploration - the Orion crew spacecraft and the Space Launch System (SLS) heavy-lift rocket that will launch Orion and large components such as in-space stages, habitat modules, landers, and other hardware necessary for deep-space operations. SLS is a key enabling capability and is designed to evolve with mission requirements. The initial configuration of SLS - Block 1 - will be capable of launching more than 70 metric tons (t) of payload into low Earth orbit, greater mass than any other launch vehicle in existence. By enhancing the propulsion elements and larger payload fairings, future SLS variants will launch 130 t into space, an unprecedented capability that simplifies hardware design and in-space operations, reduces travel times, and enhances two solid propellant five-segment boosters, both based on space shuttle technologies. This paper will focus on development of the booster, which will provide more than 75 percent of total vehicle thrust at liftoff. Each booster is more than 17 stories tall, 3.6 meters (m) in diameter and weighs 725,000 kilograms (kg). While the SLS booster appears similar to the shuttle booster, it incorporates several changes. The additional propellant segment provides additional booster performance. Parachutes and other hardware associated with recovery operations have been deleted and the booster designated as expendable for affordability reasons. The new motor incorporates new avionics, new propellant grain, asbestos-free case insulation, a redesigned nozzle, streamlined manufacturing

Simulations Of Transverse Stacking In The NSLS-II Booster

International Nuclear Information System (INIS)

Fliller, R. III; Shaftan, T.

2011-01-01

The NSLS-II injection system consists of a 200 MeV linac and a 3 GeV booster. The linac needs to deliver 15 nC in 80 - 150 bunches to the booster every minute to achieve current stability goals in the storage ring. This is a very stringent requirement that has not been demonstrated at an operating light source. We have developed a scheme to transversely stack two bunch trains in the NSLS-II booster in order to alleviate the charge requirements on the linac. This scheme has been outlined previously. In this paper we show particle tracking simulations of the tracking scheme. We show simulations of the booster ramp with a stacked beam for a variety of lattice errors and injected beam parameters. In all cases the performance of the proposed stacking method is sufficient to reduce the required charge from the linac. For this reason the injection system of the NSLS-II booster is being designed to include this feature. The NSLS-II injection system consists of a 200 MeV linac and a 3 GeV booster. The injectors must provide 7.5nC in bunch trains 80-150 bunches long every minute for top off operation of the storage ring. Top off then requires that the linac deliver 15nC of charge once losses in the injector chain are taken into consideration. This is a very stringent requirement that has not been demonstrated at an operating light source. For this reason we have developed a method to transversely stack two bunch trains in the booster while maintaining the charge transport efficiency. This stacking scheme has been discussed previously. In this paper we show the simulations of the booster ramp with a single bunch train in the booster. Then we give a brief overview of the stacking scheme. Following, we show the results of stacking two bunch trains in the booster with varying beam emittances and train separations. The behavior of the beam through the ramp is examined showing that it is possible to stack two bunch trains in the booster.

47 CFR 74.1233 - Processing FM translator and booster station applications.

Science.gov (United States)

2010-10-01

... 47 Telecommunication 4 2010-10-01 2010-10-01 false Processing FM translator and booster station... SERVICES FM Broadcast Translator Stations and FM Broadcast Booster Stations § 74.1233 Processing FM translator and booster station applications. (a) Applications for FM translator and booster stations are...

Superconducting racetrack booster for the ion complex of MEIC

Energy Technology Data Exchange (ETDEWEB)

Filatov, Yu [Joint Inst. for Nuclear Research (JINR), Dubna (Russian Federation); Moscow Inst. of Physics and Technology (MIPT), Moscow (Russian Federation); Kondratenko, A. M. [Science and Technique Laboratory ' Zaryad' , 630090, Novosibirsk, Russia; Kondratenko, M. A. [Science and Technique Laboratory ' Zaryad' , 630090, Novosibirsk, Russia; Kovalenko, A. [Joint Inst. for Nuclear Research (JINR), Dubna (Russian Federation); Derbenev, Yaroslav S. [Thomas Jefferson National Accelerator Facility (TJNAF), Newport News, VA (United States); Lin, Fanglei [Thomas Jefferson National Accelerator Facility (TJNAF), Newport News, VA (United States); Morozov, Vasiliy S. [Thomas Jefferson National Accelerator Facility (TJNAF), Newport News, VA (United States); Zhang, Yuhong [Thomas Jefferson National Accelerator Facility (TJNAF), Newport News, VA (United States)

2016-02-01

The current design of the Medium-energy Electron-Ion Collider (MEIC) project at Jefferson lab features a single 8 GeV/c figure-8 booster based on super-ferric magnets. Reducing the circumference of the booster by switching to a racetrack design may improve its performance by limiting the space charge effect and lower its cost. We consider problems of preserving proton and deuteron polarizations in a superconducting racetrack booster. We show that using magnets based on hollow high-current NbTi composite superconducting cable similar to those designed at JINR for the Nuclotron guarantees preservation of the ion polarization in a racetrack booster up to 8 GeV/c. The booster operation cycle would be a few seconds that would improve the operating efficiency of the MEIC ion complex.

Active immunisation of horses against tetanus including the booster dose and its application.

Science.gov (United States)

Liefman, C E

1981-02-01

Successful active immunisation of horses against tetanus is dependent on a number of factors of which the toxoid preparation used, its method of application and the ability of the individual horse to respond are fundamental. Two immunisation schedules using an aluminium-based toxoid preparation were examined and the protection determined by monitoring the level of antitoxin afforded by each schedule. The results obtained demonstrated that 2 doses of this toxoid are necessary to ensure 12 months protection in all horses. These results are discussed in relation to the factors involved in active immunisation against tetanus. Reference is also made to the occurrence of a transient phase of reduced levels of antitoxin following booster doses of toxoid in immunised horses during which it is considered these horses could become more susceptible to tetanus. The effect of a booster dose on immunised horses was examined and while there can be a reduction in the level of antitoxin in some immunised horses following this dose its effect is minimal, short-lived and for all practical purposes can be disregarded. The application of the booster dose in practice is also discussed.

Object-oriented programming techniques for the AGS Booster

International Nuclear Information System (INIS)

Skelly, J.F.

1991-01-01

The applications software developed for the control system of the AGS Booster Project was written in the object-oriented language, C++. A the start of the Booster Project, the programming staff of the AGS Controls Section comprised some dozen programmer/analysts, all highly fluent in C but novices in C++. During the coarse of this project, nearly the entire staff converted to using C++ for a large fraction of their assignments. Over 100 C++ software modules are now available for Booster and general AGS use, of which a large fraction are broadly applicable tools. The transition from C to C++ from a managerial perspective is discussed and an overview is provided of the ways in which object classes have been applied in Booster software development

Object-oriented programming techniques for the AGS Booster

International Nuclear Information System (INIS)

Skelly, J.F.

1992-01-01

The applications software developed for the control system of the AGS Booster Project was written in the object-oriented language, C++. At the start of the Booster Project, the programming staff of the AGS Controls Section comprised some dozen programmer/analysts, all highly fluent in C but novices in C++. During the course of this project, nearly the entire staff converted to using C++ for a large fraction of their assignments. Over 100 C++ software modules are now available both for Booster and general AGS use, of which a large fraction are broadly applicable tools. The transition from C to C++ from a managerial perspective is discussed and an overview is provided of the ways in which object classes have been applied in Booster software development. (author)

Immunogenicity and safety of a booster dose of the 13-valent pneumococcal conjugate vaccine in children primed with the 10-valent or 13-valent pneumococcal conjugate vaccine in the Czech Republic and Slovakia.

Science.gov (United States)

Urbancikova, Ingrid; Prymula, Roman; Goldblatt, David; Roalfe, Lucy; Prymulova, Karolina; Kosina, Pavel

2017-09-12

Although both the 13-valent pneumococcal conjugate vaccine (PCV13) and the 10-valent pneumococcal non-typeable Haemophilus influenzae protein D-conjugate vaccine (PHiD-CV) are widely used, it is unclear how interchangeable they are in terms of immunogenicity. Two phase 3, open-label, multicenter studies were conducted to assess the immunogenicity and safety of a booster dose of PCV13 in children primed with PHiD-CV or PCV13. In the Czech Republic, 12-15-month-old children received a PCV13 booster after 3-dose priming with either PHiD-CV or PCV13. In Slovakia, 11-12-month-old children received PCV13 following 2-dose priming with either PHiD-CV or PCV13. Serum IgG concentrations were assessed by enzyme-linked immunosorbent assay and functional antibodies were assessed by opsonophagocytic assay (OPA) before the booster and at 1 and 12months afterward. The primary objective of these studies was to assess non-inferiority of OPA titers for serotype 19A in PHiD-CV-primed subjects compared to those in PCV13-primed children 1month post-booster. A total of 98 subjects in the Czech Republic and 89 subjects in Slovakia were included. One month after the PCV13 booster dose, the IgG and OPA immune responses to serotype 19A in subjects primed with 2 or 3 doses of PHiD-CV were non-inferior to those in subjects primed with PCV13. Non-inferior and persistent immune responses to most other vaccine serotypes were also observed after the PCV13 booster in PHiD-CV-primed subjects. No safety issues were raised in either study. Overall, robust IgG and OPA immunological responses were observed after booster vaccination with PCV13 in children primed with 2 or 3 doses of PHiD-CV or PCV13, including for serotypes not included in PHiD-CV. These results suggest that these vaccines are interchangeable in terms of safety and immunogenicity and that PCV13 can be used as a booster in the context of mixed schedules. (EudraCT numbers: 2012-005366-35 and 2012-005367-27). Copyright © 2017 Elsevier Ltd

The AGS Booster control system

International Nuclear Information System (INIS)

Frankel, R.; Auerbach, E.; Culwick, B.; Clifford, T.; Mandell, S.; Mariotti, R.; Salwen, C.; Schumburg, N.

1988-01-01

Although moderate in size, the Booster construction project requires a comprehensive control system. There are three operational modes: as a high intensity proton injector for the AGS, as a heavy ion accelerator and injector supporting a wide range of ions and as a polarized proton storage injector. These requirements are met using a workstation based extension of the existing AGS control system. Since the Booster is joining a complex of existing accelerators, the new system will be capable of supporting multiuser operational scenarios. A short discussion of this system is discussed in this paper

Beam instrumentation in the AGS Booster

International Nuclear Information System (INIS)

Witkover, R.L.

1991-01-01

The AGS Booster was designed to accelerate low intensity (2 x 10 10 ) polarized protons, high intensity (1.5x10 13 ) protons and heavy ions through Au +33 . Coping with this wide range of beams, the 3 x 10 -11 Torr vacuum and the radiation environment presented challenges for the beam monitors. Some of the more interesting instrumentation design and performance during the recent Booster proton commissioning will be described

Internet Cognitive Behavioral Therapy for Women With Postnatal Depression: A Randomized Controlled Trial of MumMoodBooster.

Science.gov (United States)

Milgrom, Jeannette; Danaher, Brian G; Gemmill, Alan W; Holt, Charlene; Holt, Christopher J; Seeley, John R; Tyler, Milagra S; Ross, Jessica; Ericksen, Jennifer

2016-03-07

There are few published controlled trials examining the efficacy of Internet-based treatment for postnatal depression (PND) and none that assess diagnostic status (clinical remission) as the primary outcome. This is despite the need to improve treatment uptake and accessibility because fewer than 50% of postnatally depressed women seek help, even when identified as depressed. In a randomized controlled trial (RCT), we aimed to test the efficacy of a 6-session Internet intervention (the MumMoodBooster program, previously evaluated in a feasibility trial) in a sample of postnatal women with a clinical diagnosis of depression. The MumMoodBooster program is a cognitive behavioral therapy (CBT) intervention, is highly interactive, includes a partner website, and was supported by low-intensity telephone coaching. This was a parallel 2-group RCT (N=43) comparing the Internet CBT treatment (n=21) to treatment as usual (n=22). At baseline and at 12 weeks after enrollment, women's diagnostic status was assessed by telephone with the Standardized Clinical Interview for DSM-IV (SCID-IV) and symptom severity with the Beck Depression Inventory (BDI-II). Depression symptoms were measured repeatedly throughout the study period with the Patient Health Questionnaire (PHQ-9). At the end of the study, 79% (15/19) of women who received the Internet CBT treatment no longer met diagnostic criteria for depression on the SCID-IV (these outcome data were missing for 2 intervention participants). This contrasted with only 18% (4/22) remission in the treatment as usual condition. Depression scores on the BDI-II showed a large effect favoring the intervention group (d=.83, 95% CI 0.20-1.45). Small to medium effects were found on the PHQ-9 and on measures of anxiety and stress. Adherence to the program was very good with 86% (18/21) of users completing all sessions; satisfaction with the program was rated 3.1 out of 4 on average. Our results suggest that our Internet CBT program, MumMoodBooster

Booster Vaccination: The Role of Reduced Antigen Content Vaccines as a Preschool Booster

Directory of Open Access Journals (Sweden)

Giovanni Gabutti

2014-01-01

Full Text Available The need for boosters for tetanus, diphtheria, pertussis, and polio, starting from preschool age, is related to the waning immune protection conferred by vaccination, the elimination/reduction of natural boosters due to large-scale immunization programs, and the possibility of reintroduction of wild agents from endemic areas. Taking into account the relevance of safety/tolerability in the compliance with vaccination among the population, it have been assessed whether today enough scientific evidences are available to support the use of dTap-IPV booster in preschool age. The review of the literature was conducted using the PubMed search engine. A total of 41 works has been selected; besides, the documentation produced by the World Health Organization, the European Centre for Disease Control, and the Italian Ministry of Health has been consulted. Many recent papers confirm the opportunity to use a low antigenic dose vaccine starting from 4 to 6 years of age. There is also evidence that 10 years after immunization the rate of seroprotected subjects against diphtheria does not differ significantly between those vaccinated with paediatric dose (DTaP or reduced dose (dTaP or dTap product. The dTpa vaccine is highly immunogenic for diphtheria toxoids regardless of prior vaccination history (2 + 1 and 3 + 1 schedules.

Subcriticality determination in ADS: Valina-Booster experiments

International Nuclear Information System (INIS)

Persson, C. M.; Gudowski, W.; Fokau, A.; Bournos, V.; Fokov, Y.; Routkovskaia, C.; Serafimovich, I.; Kiyavitskaya, H.

2007-01-01

A major problem in operating a full-scale subcritical accelerator-driven system (ADS) is to ensure sufficient margin to criticality. Therefore, reliable techniques for subcriticality monitoring are required. In order to develop such techniques, a full understanding of existing reactivity determination methods is essential. In this work, reactivity determination methods, such as pulsed neutron source methods and noise methods, are studied experimentally in the subcritical facility YALINA-Booster. YALINA-Booster: The subcritical assembly YALINA-Booster: recently constructed at the Joint Institute for Power and Nuclear Research - Sosny, consists of a subcritical core driven by an external neutron source. The neutron source is a powerful neutron generator consisting of a deuteron accelerator and a target of deuterium or tritium embedded in titanium. Through (d, d) - or (d, t)-reactions neutrons are created with energy around 2.5 MeV and 14.1 MeV respectively. Neutrons are born in the centre of the core and multiply through a lead matrix fuelled with highly enriched uranium (90% and 36%). This zone is referred to as the booster zone and is surrounded by a thermal zone, moderated by polyethylene. In order to reach sufficient high effective multiplication factor, the thermal zone is fuelled by approximately one thousand rods of 10% enriched uranium dioxide in cylindrical geometry. To prevent thermal neutrons from diffusing into the fast booster zone, an interface, consisting of boron carbide and natural uranium rods, is located between the zones. YALINA-Booster has a radial graphite reflector of thickness 24 cm. Experiments: Experiments using the neutron source in pulsed mode will be presented, relying on methods such as the area method and the method of prompt neutron decay rate determination. Moreover, results from noise analysis using for instance the Feynman-α method will be presented

Immune responses of bison and efficacy after booster vaccination with Brucella abortus strain RB51

Science.gov (United States)

Thirty-one bison heifers were randomly assigned to saline (control; n=7) or single vaccination (n=24) with 1010 CFU of B. abortus strain RB51 (RB51). Some vaccinated bison were randomly selected for booster vaccination with 10**10 CFU of RB51 at 11 months after initial vaccination (n=16). When comp...

Clinical and economic assessment of different general population strategies of pertussis vaccine booster regarding number of doses and age of application for reducing whooping cough disease burden: a systematic review.

Science.gov (United States)

Rodríguez-Cobo, Iria; Chen, Yen-Fu; Olowokure, Babatunde; Litchfield, Ian

2008-12-09

Pertussis continues to be an important cause of morbidity and mortality in children too young to be fully protected despite high vaccination coverage. This has been attributed to waning immunity in older people, leading to the development of strategies to increase levels of immunity. A systematic review was conducted to assess the clinical and cost effectiveness of four population-based strategies for pertussis booster vaccination: single booster at 12-24 months old, single pre-school booster, single adolescent booster and multiple boosters in adulthood every 10 years. Electronic databases and Internet resources were searched to June 2006. Nine observational studies, four mathematical models and eight economic evaluations were included, evaluating four different strategies. Strong evidence to recommend any of these strategies was not found.

SIMULATIONS OF BOOSTER INJECTION EFFICIENCY FOR THE APS-UPGRADE

Energy Technology Data Exchange (ETDEWEB)

Calvey, J.; Borland, M.; Harkay, K.; Lindberg, R.; Yao, C.-Y.

2017-06-25

The APS-Upgrade will require the injector chain to provide high single bunch charge for swap-out injection. One possible limiting factor to achieving this is an observed reduction of injection efficiency into the booster synchrotron at high charge. We have simulated booster injection using the particle tracking code elegant, including a model for the booster impedance and beam loading in the RF cavities. The simulations point to two possible causes for reduced efficiency: energy oscillations leading to losses at high dispersion locations, and a vertical beam size blowup caused by ions in the Particle Accumulator Ring. We also show that the efficiency is much higher in an alternate booster lattice with smaller vertical beta function and zero dispersion in the straight sections.

Space shuttle booster separation motor design

Science.gov (United States)

Smith, G. W.; Chase, C. A.

1976-01-01

The separation characteristics of the space shuttle solid rocket boosters (SRBs) are introduced along with the system level requirements for the booster separation motors (BSMs). These system requirements are then translated into specific motor requirements that control the design of the BSM. Each motor component is discussed including its geometry, material selection, and fabrication process. Also discussed is the propellant selection, grain design, and performance capabilities of the motor. The upcoming test program to develop and qualify the motor is outlined.

A Randomized Controlled Study of a Fully Liquid DTaP-IPV-HB-PRP-T Hexavalent Vaccine for Primary and Booster Vaccinations of Healthy Infants and Toddlers in Latin America.

Science.gov (United States)

López, Pío; Arguedas Mohs, Adriano; Abdelnour Vásquez, Arturo; Consuelo-Miranda, Maria; Feroldi, Emmanuel; Noriega, Fernando; Jordanov, Emilia; B Chir, Siham; Zambrano, Betzana

2017-11-01

Hexavalent diphtheria-tetanus-acellular pertussis-inactivated poliovirus-hepatitis B-Haemophilus influenzae type b (DTaP-IPV-HB-PRP-T)-containing vaccines are increasingly the standard of care. This study evaluated the primary series (NCT01177722) and booster (NCT01444781) of a fully liquid DTaP-IPV-HB-PRP-T vaccine in Latin America. Infants (N = 1375) received hepatitis B vaccine at birth and were randomized to one of 3 batches of the investigational DTaP-IPV-HB-PRP-T or licensed control vaccine (DTaP-HB-IPV//PRP-T) at 2-4 to 6 months of age, coadministered with 7-valent pneumococcal conjugate vaccine (PCV7) (2-4-6 months) and rotavirus vaccine (2-4 months). A booster of either DTaP-IPV-HB-PRP-T or control was given at 12-24 months, coadministered with PCV7. Immunogenicity was assessed by validated assays and safety from parental reports. Primary series seroprotection and vaccine response rates were equivalent for DTaP-IPV-HB-PRP-T batches. For pooled batches, noninferiority to the control vaccine was demonstrated for each antigen. There were no descriptive differences in antibody persistence or booster response between DTaP-IPV-HB-PRP-T and the control. The booster responses to either vaccine following DTaP-IPV-HB-PRP-T primary series or to DTaP-IPV-HB-PRP-T following a control vaccine primary series were similar. The anti-aP component (filamentous hemagglutinin [FHA] and pertussis toxin [PT]) vaccine response and anti-Haemophilus influenzae type b (PRP) series seroprotection (≥0.15 µg/mL) rates were ≥73.0% after 2 primary series doses. Antipyretics had no effect on the immune response, and an extra (oral) polio vaccination had no effect on the antipolio booster response. Responses to PCV7 and rotavirus vaccine were similar for each coadministration. There were no safety concerns observed with any vaccine. These results confirm the suitability of the fully liquid DTaP-IPV-HB-PRP-T vaccine for primary and booster vaccination of infants.

The AGS Booster main ring power supply system

International Nuclear Information System (INIS)

Soukas, A.; Hughes, K.; Sandberg, J.; Toldo, F.; Zhang, S.Y.

1989-01-01

The AGS Booster is being designed as a very versatile particle accelerator. Its primary function is to be a high quality injector to the currently operating Alternating Gradient Synchrotron (AGS). The Booster/AGS combination will produce proton intensities greater than 5 x 10 13 protons per pulse (ppp), and accelerate heavy ions, with mass up to 200, to a maximum energy of 15 GeV per atomic mass unit (GeV/amu). The power supply for the Booster Main Ring (BMRPS) has to accommodate a wide range of cycles and a wide range of operating parameters. The cycles range from storage for several seconds to rapid cycling at 7.5 Hz. The peak output power is 18 MW. This paper will describe the AGS Booster machine powering requirements, the choice of power supply, the a.c. circuit tie-in and its associated problems and some of the details of the design of the BMRPS. 9 refs., 2 figs

A fully liquid DTaP-IPV-HB-PRP-T hexavalent vaccine for primary and booster vaccination of healthy Turkish infants and toddlers

Science.gov (United States)

Ceyhan, Mehmet; Yıldırım, İnci; Tezer, Hasan; Devrim, İlker; Feroldi, Emmanuel

2017-08-23

Background/aim: Immunogenicity and safety of a primary series of a fully liquid, hexavalent DTaP-IPV-HB-PRP-T vaccine given at 2, 3, and 4 months of age compared to licensed comparators and a DTaP-IPV-HB-PRP-T booster at 15?18 months were evaluated. Materials and methods: This was a Phase III, randomized, open-label trial. Primary series (no hepatitis B [HB] at birth) of DTaP-IPV-HB-PRP-T (N = 155) (group 1) or licensed control vaccines (DTaP-IPV//PRP-T and standalone HB: N = 155) (group 2) and DTaP-IPV-HB-PRP-T booster were administered. Noninferiority was evaluated 1 month postprimary series for anti-HB seroprotection (SP). All other analyses were descriptive. Safety was assessed from parental reports. Results: Postprimary series noninferiority of anti-HB ≥ 10 mIU/mL was demonstrated for the DTaP-IPV-HB-PRP-T vaccine (94.0%) compared to the licensed control (96.1%). Postprimary series primary SP and seroconversion (SC) rates were high and similar for both groups. Antibody persistence (prebooster) was high for each antigen and similar between groups except for HB, which was lower for DTaP-IPV-HB-PRP-T than for standalone HB. For each antigen except HB, DTaP-IPV-HB-PRP-T booster responses were high and similar in each group. Safety was good for primary and booster series and similar between groups. Conclusion: The DTaP-IPV-HB-PRP-T vaccine is immunogenic and safe when administered in a challenging primary series schedule without HB vaccination at birth.

Advocacy for booster seat legislation in Florida: a lesson in politics and policy formation.

Science.gov (United States)

Haring, R Sterling; Frattaroli, Shannon; Schneider, Eric B; Holland, M Becker; Vernick, Jon S

2015-04-01

MVCs are a major contributor to child injury and death. Infant restraint seats and child booster seats have been shown to reduce the odds of severe injury or death when used correctly. While all states have mandated the use of these restraint systems, the age at which a child can be legally restrained using an adult seat belt varies from state to state. Efforts to strengthen Florida's weak child restraint laws have failed for more than a decade; in the 2014 legislative session, advocates succeeded in raising the state's age requirement from 3 years to 5  years. While many factors contributed to this year's success, some key elements included efficient communication of supporting data, a strong and broad advocacy network and the leveraging of election year political rivalries. Efforts to further strengthen the law will continue into future legislative sessions. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions.

A fully liquid DTaP-IPV-Hep B-PRP-T hexavalent vaccine for primary and booster vaccination of healthy Mexican children.

Science.gov (United States)

Aquino, Amalia Guadalupe Becerra; Brito, Maricruz Gutiérrez; Doniz, Carlos E Aranza; Herrera, Juan Francisco Galán; Macias, Mercedes; Zambrano, Betzana; Plennevaux, Eric; Santos-Lima, Eduardo

2012-10-05

To evaluate an investigational, fully liquid hexavalent diphtheria-tetanus-acellular pertussis-inactivated poliovirus-hepatitis B-Haemophilus influenzae type b (DTaP-IPV-Hep B-PRP-T: Hexaxim™) vaccine for primary and booster vaccination of healthy children in Mexico. Infants (N=1189) were randomized to receive one of three lots of the DTaP-IPV-Hep B-PRP-T vaccine or a licensed hexavalent control vaccine (Infanrix™ hexa) for primary vaccination at 2, 4 and 6 months. All participants who completed the primary series and agreed to participate in the booster part of the study received a dose of the investigational vaccine at 15-18 months of age. Validated serological assays and parental reports were used to assess immunogenicity and safety, respectively. Post-primary vaccination, ≥95.8% of participants in both the DTaP-IPV-Hep B-PRP-T and control groups were seroprotected (SP) against diphtheria, tetanus, poliovirus, hepatitis B and PRP, or had seroconverted (SC) to the pertussis toxin (PT) and filamentous hemagglutinin (FHA) pertussis antigens. The SP/SC rates induced by the three DTaP-IPV-Hep B-PRP-T lots were equivalent. No differences in SP/SC rates were observed between the pooled lots of investigational vaccine and the control vaccine. Antibody persistence at 15-18 months was comparable between groups, with strong increases in all antibody concentrations post-DTaP-IPV-Hep B-PRP-T booster. Both vaccines were well tolerated for primary vaccination, as was the booster dose of DTaP-IPV-Hep B-PRP-T. These study findings confirm the suitability of the combined, fully liquid DTaP-IPV-Hep B-PRP-T vaccine for inclusion in routine childhood vaccination schedules. Copyright © 2012 Elsevier Ltd. All rights reserved.

An efficiency booster for energy conversion in natural circulation loops

Energy Technology Data Exchange (ETDEWEB)

Wang, Dongqing, E-mail: wangdongqing@stu.xjtu.edu.cn [School of Nuclear Science and Technology, Xi’an Jiaotong University, Xi’an, Shaanxi 710049 (China); Beijing Computational Science Research Center, Beijing 100084 (China); Jiang, Jin, E-mail: jjiang@eng.uwo.ca [Department of Electrical and Computer Engineering, The University of Western Ontario, London, Ontario N6A 5B9 (Canada); Beijing Computational Science Research Center, Beijing 100084 (China)

2016-08-01

Highlights: • Low driving power conversion efficiency of natural circulation loops is proved. • The low conversion efficiency leads to low heat transfer capacity of such loops. • An efficiency booster is designed with turbine to increase the efficiency. • Performance of the proposed booster has been numerically simulated. • The booster drastically enhances heat transfer capacity of such loops. - Abstract: In this paper, the capacity of a natural circulation loop for transferring heat from a heat source to a heat sink has been analyzed. It is concluded that the capacity of the natural circulation loop depends on the conversion efficiency of the thermal energy from the heat source to the driving force for the circulation of the flow. The low conversion efficiency leading to weak driving force in such loops has been demonstrated analytically and validated through simulation results. This issue has resulted in a low heat transfer capacity in the circulation loop. To increase the heat transfer capacity, one has to improve this efficiency. To meet such a need, a novel efficiency booster has been developed in this paper. The booster essentially increases the flow driving force and hence significantly improves the overall heat transfer capacity. Design and analysis of this booster have been performed in detail. The performance has been examined through extensive computer simulations. It is concluded that the booster can indeed drastically improve the heat transfer capacity of the natural circulation loop.

An efficiency booster for energy conversion in natural circulation loops

International Nuclear Information System (INIS)

Wang, Dongqing; Jiang, Jin

2016-01-01

Highlights: • Low driving power conversion efficiency of natural circulation loops is proved. • The low conversion efficiency leads to low heat transfer capacity of such loops. • An efficiency booster is designed with turbine to increase the efficiency. • Performance of the proposed booster has been numerically simulated. • The booster drastically enhances heat transfer capacity of such loops. - Abstract: In this paper, the capacity of a natural circulation loop for transferring heat from a heat source to a heat sink has been analyzed. It is concluded that the capacity of the natural circulation loop depends on the conversion efficiency of the thermal energy from the heat source to the driving force for the circulation of the flow. The low conversion efficiency leading to weak driving force in such loops has been demonstrated analytically and validated through simulation results. This issue has resulted in a low heat transfer capacity in the circulation loop. To increase the heat transfer capacity, one has to improve this efficiency. To meet such a need, a novel efficiency booster has been developed in this paper. The booster essentially increases the flow driving force and hence significantly improves the overall heat transfer capacity. Design and analysis of this booster have been performed in detail. The performance has been examined through extensive computer simulations. It is concluded that the booster can indeed drastically improve the heat transfer capacity of the natural circulation loop.

New beam instrumentation in the AGS Booster

International Nuclear Information System (INIS)

Witkover, R.L.

1991-01-01

The AGS Booster was designed to accelerate beams from 2x10 10 polarized protons to 1.5x10 13 protons and heavy ions through Au +33 . The range of beam parameters and the high vacuum, and radiation environment presented challenges for the beam instrumentation. Some interesting beam monitors in the Booster and transport lines, will be described. Where available, results will be presented. 21 refs., 7 figs

Hepatitis A vaccine. A new convenient single-dose schedule with booster when long-term immunization is warranted

DEFF Research Database (Denmark)

Victor, J; Knudsen, J D; Nielsen, L P

1994-01-01

A total of 162 anti-HAV-negative healthy adults were immunized with a single high dose (1440 ELISA units = 1 ml) of inactivated hepatitis A vaccine and a booster was given at month 6. Antibodies were measured after modification of a commercial ELISA kit, enabling quantification of titres down to 6...

Accelerating RF cavity of the Booster

CERN Multimedia

CERN PhotoLab

1981-01-01

Each of the 4 PS Booster rings has a single accelerating cavity. It consists of 2 quarter-wave ferrite-loaded resonators. There are 2 figure-of-eight loops on the ferrite loads for tuning the frequency throughout the acceleration cycle, from 3 to 8 MHz (from 50 MeV at injection to the original Booster energy of 800 MeV, 2 GeV today). The cavities have a flat design, to fit the ring-to-ring distance of 36 cm. The tube for forced-air cooling is visible in the left front. See also 8301084.

Accelerating RF cavity of the Booster

CERN Multimedia

CERN PhotoLab

1983-01-01

Each of the 4 PS Booster rings has a single accelerating cavity.It consists of 2 quarter-wave ferrite-loaded resonators. 2 figure-of-eight loops tune the frequency throughout the accelerating cycle, from 3 to 8 MHz (from 50 MeV at injection to the original Booster energy of 800 MeV, 2 GeV today). The cavities have a flat design, to fit the ring-to-ring distance of 36 cm, and are forced-air cooled. The 2 round objects in the front-compartments are the final-stage power-tetrodes. See also 8111095.

Weak Depolarizing Resonances in the 3-TeV VLHC Booster

International Nuclear Information System (INIS)

Anferov, V.A.

1999-01-01

The possibility of polarized-proton-beam acceleration in the proposed low-field 3-TeV VLHC booster is considered. We find that the low-field combined function magnets in the booster's long FODO cells cause an inadvertent cancellation of most depolarizing fields due to a mechanism suggested earlier by Chao and Derbenev [Part.Accel.36, 25 (1991)]. The strongest spin-depolarizing resonances in the 3-TeV booster seem to be similar in strength to those in the 250-GeV RHIC. Moreover, the strength of the 3-TeV booster's strongest intrinsic depolarizing resonances decreases with energy, in contrast with the energy growth of the depolarizing resonance's strength in most proton synchrotrons. copyright 1999 The American Physical Society

Diamond Light Source Booster fast orbit feedback system

International Nuclear Information System (INIS)

Gayadeen, S.; Duncan, S.R.; Christou, C.; Heron, M.T.; Rowland, J.

2012-01-01

The Fast Orbit Feedback system that has been installed on the Diamond Light Source Storage ring has been replicated on the Booster synchrotron in order to provide a test bed for the development of the Storage Ring controller design. To realise this the Booster is operated in DC mode. The electron beam is regulated in two planes using the Fast Orbit Feedback system, which takes the beam position from 22 beam position monitors for each plane, and calculates offsets to 44 corrector power supplies at a sample rate of 10 kHz. This paper describes the design and realization of the controller for the Booster Fast Orbit Feedback, presents results from the implementation and considers future development

New beam instrumentation in the AGS Booster

Energy Technology Data Exchange (ETDEWEB)

Witkover, R.L.

1991-01-01

The AGS Booster was designed to accelerate beams from 2{times}10{sup 10} polarized protons to 1.5{times}10{sup 13} protons and heavy ions through Au{sup +33}. The range of beam parameters and the high vacuum, and radiation environment presented challenges for the beam instrumentation. Some interesting beam monitors in the Booster and transport lines, will be described. Where available, results will be presented. 21 refs., 7 figs.

Performance evaluation of DAAF as a booster material using the onionskin test

Energy Technology Data Exchange (ETDEWEB)

Morris, John S [Los Alamos National Laboratory; Francois, Elizabeth G [Los Alamos National Laboratory; Hooks, Daniel E [Los Alamos National Laboratory; Hill, Larry G [Los Alamos National Laboratory; Harry, Herbert H [Los Alamos National Laboratory

2010-12-02

Initiation of insensitive high explosive (IHE) formulations requires the use of a booster explosive in the initiation train. Booster material selection is crucial, as the initiation must reliably function across some spectrum of physical parameters. The interest in Diaminoazoxyfurazan (DAAF) for this application stems from the fact that it possesses many traits of an IHE but is shock sensitive enough to serve as an explosive booster. A hemispherical wave breakout test, termed the onionskin test, is one of the methods used to evaluate the performance of a booster material. The wave breakout time-position history at the surface of a hemispherical IHE charge is recorded and the relative uniformity of the breakout can be quantitatively compared between booster materials. A series of onionskin tests were performed to investigate breakout and propagation diaminoazoxyfurazan (DAAF) at low temperatures to evaluate ignition and detonation spreading in comparison to other explosives commonly used in booster applications. Some wave perturbation was observed with the DAAF booster in the onionskin tests presented. The results of these tests will be presented and discussed.

Booster Main Engine Selection Criteria for the Liquid Fly-Back Booster

Science.gov (United States)

Ryan, Richard M.; Rothschild, William J.; Christensen, David L.

1998-01-01

The Liquid Fly-Back Booster (LFBB) Program seeks to enhance the Space Shuttle system safety performance and economy of operations through the use of an advanced, liquid propellant Booster Main Engine (BME). There are several viable BME candidates that could be suitable for this application. The objective of this study was to identify the key criteria to be applied in selecting among these BME candidates. This study involved an assessment of influences on the overall LFBB utility due to variations in the candidate rocket engines' characteristics. This includes BME impacts on vehicle system weight, perfortnance,design approaches, abort modes, margins of safety, engine-out operations, and maintenance and support concepts. Systems engineering analyses and trade studies were performed to identify the LFBB system level sensitivities to a wide variety of BME related parameters. This presentation summarizes these trade studies and the resulting findings of the LFBB design teams regarding the BME characteristics that most significantly affect the LFBB system. The resulting BME choice should offer the best combination of reliability, performance, reusability, robustness, cost, and risk for the LFBB program.

Space Launch System Accelerated Booster Development Cycle

Science.gov (United States)

Arockiam, Nicole; Whittecar, William; Edwards, Stephen

2012-01-01

With the retirement of the Space Shuttle, NASA is seeking to reinvigorate the national space program and recapture the public s interest in human space exploration by developing missions to the Moon, near-earth asteroids, Lagrange points, Mars, and beyond. The would-be successor to the Space Shuttle, NASA s Constellation Program, planned to take humans back to the Moon by 2020, but due to budgetary constraints was cancelled in 2010 in search of a more "affordable, sustainable, and realistic" concept2. Following a number of studies, the much anticipated Space Launch System (SLS) was unveiled in September of 2011. The SLS core architecture consists of a cryogenic first stage with five Space Shuttle Main Engines (SSMEs), and a cryogenic second stage using a new J-2X engine3. The baseline configuration employs two 5-segment solid rocket boosters to achieve a 70 metric ton payload capability, but a new, more capable booster system will be required to attain the goal of 130 metric tons to orbit. To this end, NASA s Marshall Space Flight Center recently released a NASA Research Announcement (NRA) entitled "Space Launch System (SLS) Advanced Booster Engineering Demonstration and/or Risk Reduction." The increased emphasis on affordability is evident in the language used in the NRA, which is focused on risk reduction "leading to an affordable Advanced Booster that meets the evolved capabilities of SLS" and "enabling competition" to "enhance SLS affordability. The purpose of the work presented in this paper is to perform an independent assessment of the elements that make up an affordable and realistic path forward for the SLS booster system, utilizing advanced design methods and technology evaluation techniques. The goal is to identify elements that will enable a more sustainable development program by exploring the trade space of heavy lift booster systems and focusing on affordability, operability, and reliability at the system and subsystem levels5. For this study

Immunogenicity and Reactogenicity of DTPa-IPV/Hib Vaccine Co-administered With Hepatitis B Vaccine for Primary and Booster Vaccination of Taiwanese Infants

Directory of Open Access Journals (Sweden)

Pei-Lan Shao

2011-06-01

Full Text Available Immunogenicity and reactogenicity of the combined diphtheria-tetanus-acellular pertussis-inactivated poliovirus-Haemophilus influenzae type b (Hib conjugate vaccine (DTPa-IPV/Hib, Infanrix™-IPV + Hib was assessed when co-administered with hepatitis B (HBV vaccine. Seventy healthy infants received DTPa-IPV/Hib at 1.5, 3.5, 6 and 15–18 months, and HBV at birth, 1.5, 6 and 15–18 months of age. Serological responses were assessed. Diphtheria, tetanus, Hib and pertussis seroprotection/seropositivity rates were 100% after primary vaccination. Post-primary immune responses to poliovirus could not be evaluated for technical reasons. However, after the booster dose, seroprotection/seropositivity rates, including poliovirus, were 100%. Over 95% were seroprotected against HBV. Post-booster geometric mean antibody concentrations/titers (GMC/GMTs rose from 14-fold to 45-fold, indicating effective priming against all antigens, including polioviruses. DTPa-IPV/Hib was well tolerated alone or co-administered with HBV. No serious adverse events were considered related to vaccination. Primary and booster vaccination with combined DTPa-IPV/Hib and HBV was immunogenic and well tolerated. Combination vaccines enable vaccine providers to conveniently provide routine pediatric immunizations, with minimal discomfort.

Long-Term Safety and Immunogenicity of a Tetravalent Live-Attenuated Dengue Vaccine and Evaluation of a Booster Dose Administered to Healthy Thai Children.

Science.gov (United States)

Watanaveeradej, Veerachai; Simasathien, Sriluck; Mammen, Mammen P; Nisalak, Ananda; Tournay, Elodie; Kerdpanich, Phirangkul; Samakoses, Rudiwilai; Putnak, Robert J; Gibbons, Robert V; Yoon, In-Kyu; Jarman, Richard G; De La Barrera, Rafael; Moris, Philippe; Eckels, Kenneth H; Thomas, Stephen J; Innis, Bruce L

2016-06-01

We evaluated the safety and immunogenicity of two doses of a live-attenuated, tetravalent dengue virus vaccine (F17/Pre formulation) and a booster dose in a dengue endemic setting in two studies. Seven children (7- to 8-year-olds) were followed for 1 year after dose 2 and then given a booster dose (F17/Pre formulation), and followed for four more years (Child study). In the Infant study, 49 2-year-olds, vaccinated as infants, were followed for approximately 3.5 years after dose 2 and then given a booster dose (F17) and followed for one additional year. Two clinically notable events were observed, both in dengue vaccine recipients in the Infant study: 1 case of dengue approximately 2.7 years after dose 2 and 1 case of suspected dengue after booster vaccinations. The booster vaccinations had a favorable safety profile in terms of reactogenicity and adverse events reported during the 1-month follow-up periods. No vaccine-related serious adverse events were reported during the studies. Neutralizing antibodies against dengue viruses 1-4 waned during the 1-3 years before boosting, which elicited a short-lived booster response but did not provide a long-lived, multivalent antibody response in most subjects. Overall, this candidate vaccine did not elicit a durable humoral immune response. © The American Society of Tropical Medicine and Hygiene.

High-level immunogenicity is achieved vaccine with adjuvanted pandemic H1N1(2009) and improved with booster dosing in a randomized trial of HIV-infected adults.

Science.gov (United States)

Cooper, Curtis; Klein, Marina; Walmsley, Sharon; Haase, David; MacKinnon-Cameron, Donna; Marty, Kimberley; Li, Yan; Smith, Bruce; Halperin, Scott; Law, Barb; Scheifele, David

2012-01-01

More severe influenza disease and poor vaccine immunogenicity in HIV-infected patients necessitate improved immunization strategies to maximize vaccine efficacy. A phase III, randomized trial was conducted at 4 Canadian sites. Two dosing strategies (standard dose vs standard dose plus booster on day 21) were assessed in HIV patients aged 20 to 59 years during the H1N1(2009) pandemic. A single antigen, inactivated split adjuvanted (AS03(A)) influenza vaccine (Arepanrix) was utilized. Serum hemagglutination inhibition (HAI) titres were assessed at days 21 and 42 and at month 6. 150 participants received at least one injection. Baseline parameters were similar between groups: 83% male, 85% on HAART, median CD4 = 519 cells/mm(3), 84% with HIV RNA < 50 copies/mL. At day 21, seroprotection (HAI ≥1:40) was achieved in 80% (95% CI, 70-89) of participants. Seroconversion occurred in 74% (63-85). Seroprotection and seroconversion were further improved in those randomized to booster dosing: day 42, 94% (85-98) versus 73% (60-83) (P < .01) and 86% (75-93) versus 66% (5-77) (P = .01). Seroprotec-tion was retained in 40% (28-54) of recipients at month 6 with trends toward greater retention of immunity in booster recipients. High-level immunogenicity was achieved with a single dose of this adjuvanted vaccine. Immunogenicity was further improved with booster dosing. Use of this adjuvanted vaccine and booster represent an important approach to increasing immunogenicity in this vaccine hypo-responsive population.

Booster parameter list

International Nuclear Information System (INIS)

Parsa, Z.

1986-10-01

The AGS Booster is designed to be an intermediate synchrotron injector for the AGS, capable of accelerating protons from 200 MeV to 1.5 GeV. The parameters listed include beam and operational parameters and lattice parameters, as well as parameters pertaining to the accelerator's magnets, vacuum system, radio frequency acceleration system, and the tunnel. 60 refs., 41 figs

Long-term evaluation of mucosal and systemic immunity and protection conferred by different polio booster vaccines.

Science.gov (United States)

Xiao, Yuhong; Daniell, Henry

2017-09-25

Oral polio vaccine (OPV) and Inactivated Polio Vaccine (IPV) have distinct advantages and limitations. IPV does not provide mucosal immunity and introduction of IPV to mitigate consequences of circulating vaccine-derived polio virus from OPV has very limited effect on transmission and OPV campaigns are essential for interrupting wild polio virus transmission, even in developed countries with a high coverage of IPV and protected sewer systems. The problem is magnified in many countries with limited resources. Requirement of refrigeration for storage and transportation for both IPV and OPV is also a major challenge in developing countries. Therefore, we present here long-term studies on comparison of a plant-based booster vaccine, which is free of virus and cold chain with IPV boosters and provide data on mucosal and systemic immunity and protection conferred by neutralizing antibodies. Mice were primed subcutaneously with IPV and boosted orally with lyophilized plant cells containing 1μg or 25μg polio viral protein 1 (VP1), once a month for three months or a single booster one year after the first prime. Our results show that VP1-IgG1 titers in single or double dose IPV dropped to background levels after one year of immunization. This decrease correlated with >50% reduction in seropositivity in double dose and <10% seropositivity in single dose IPV against serotype 1. Single dose IPV offered no or minimal protection against serotype 1 and 2 but conferred protection against serotype 3. VP1-IgA titers were negligible in IPV single or double dose vaccinated mice. VP1 antigen with two plant-derived adjuvants induced significantly high level and long lasting VP1-IgG1, IgA and neutralizing antibody titers (average 4.3-6.8 log2 titers). Plant boosters with VP1 and plant derived adjuvants maintained the same level titers from 29 to 400days and conferred the same level of protection against all three serotypes throughout the duration of this study. Even during period, when

Mathematical modeling of compression processes in air-driven boosters

International Nuclear Information System (INIS)

Li Zeyu; Zhao Yuanyang; Li Liansheng; Shu Pengcheng

2007-01-01

The compressed air in normal pressure is used as the source of power of the air-driven booster. The continuous working of air-driven boosters relies on the difference of surface area between driven piston and driving piston, i.e., the different forces acting on the pistons. When the working surface area of the driving piston for providing power is greater than that of the driven piston for compressing gas, the gas in compression chamber will be compressed. On the basis of the first law of thermodynamics, the motion regulation of piston is analyzed and the mathematical model of compression processes is set up. Giving a calculating example, the vary trends of gas pressure and pistons' move in working process of booster have been gotten. The change of parameters at different working conditions is also calculated and compared. And the corresponding results can be referred in the design of air-driven boosters

Booster fans : some considerations for their usage in underground coal mines

Energy Technology Data Exchange (ETDEWEB)

Gillies, S.; Slaughter, C. [Missouri Univ. of Science and Technology, Rolla, MO (United States); Calizaya, F. [Utah Univ., Salt Lake City, UT (United States); Wu, H.W. [Gillies Wu Mining Technology Pty Ltd., Brisbane, QLD (Australia)

2010-07-01

This paper reported on a study that investigated the conditions under which booster fans can be used safely and efficiently in underground coal mines. Booster fans are installed in series with a main surface fan and are used to boost the air pressure of the ventilation air passing through it. Several coal mining countries use booster fans, but in the United States, they are only used in metal/non-metal mines due to concerns of uncontrolled recirculation. This study investigated installations of booster fans in non-US underground coal mines where safe and efficient atmospheric conditions are achieved. The purpose was to collect reliable information on airway resistances and flow requirements typical in large US coal mines. The study showed that safe booster fan installations are found in both high and low gas conditions, and sometimes where workings are located at great depths. The interlocking systems within the booster fan can control the underground fans and avoid recirculation when surface fans are unexpectedly turned off. Another purpose of the study was to determine when booster fans become a more viable solution in coal mines due to increases in air requirements at higher production rates. It was concluded that a new fan selection algorithm to produce recirculation-free ventilation designs will be developed to enable US coal mine operators to develop ventilation designs to extract coal seams from depths greater than 1000 m. 17 refs., 1 fig.

Ram booster

Science.gov (United States)

Brand, Vance D. (Inventor); Morgan, Walter Ray (Inventor)

2011-01-01

The present invention is a space launch system and method to propel a payload bearing craft into earth orbit. The invention has two, or preferably, three stages. The upper stage has rocket engines capable of carrying a payload to orbit and provides the capability of releasably attaching to the lower, or preferably, middle stage. Similar to the lower stage, the middle stage is a reusable booster stage that employs all air breathing engines, is recoverable, and can be turned-around in a short time between missions.

Proposed data acquisition system for the Fermilab Booster

International Nuclear Information System (INIS)

Bharadwaj, V.; Peggs, S.; Wu, G.; Saltmarsh, C.

1991-01-01

At present, studies involving the FNAL Booster (or in fact most accelerators) depend on knowing exactly what detector one has to look at and at what time. Because of this, most studies are done 'on-line' and involve looking for repetitive effects using a limited number of detectors. In this paper the authors propose to design a Booster Data Acquisition System (BDAQ) for the FNAL Booster. In essence this system consists of a large number of digitizers with circular memory buffers. After a machine cycle of interest, these buffers are frozen and then read out into a mass storage device. This paper discusses the hardware and software capabilities needed to make such a data acquisition system a powerful tool for doing accelerator physics studies and improving machine performance

Rapid cycling superconducting booster synchrotron

International Nuclear Information System (INIS)

Dinev, D.; Agapov, N.; Butenko, A.

2001-01-01

The existing set of Nuclotron heavy ion sources, such as duoplasmatron, polarized deuteron, laser and electron beam ion sources permits to have ion beams over a wide range of masses. The main problem for us now is to gain high intensity of accelerator particles. It can be solved by means of multiturn injection of the low current beams into the booster, acceleration up to the intermediate energies, stripping and transferring into the main ring. A design study of this accelerator - the 250 MeV/Amu Nuclotron booster synchrotron at 1 Hz repetition rate and circumference of 84 m, has been completed. The lattice dipole and quadrupole magnets have an iron yoke coils, made of hollow superconductor, are cooled by two-phase Helium flow, as well as the Nuclotron magnets. (authors)

AHF Booster Tracking with SIMPSONS.

Energy Technology Data Exchange (ETDEWEB)

Johnson, D. E. (David E.); Neri, F. (Filippo)

2002-01-01

The booster lattice for the Advanced Hydrotest Facility at Los Alamos was tracked in 3-D with the program SIMPSONS, using the full, symplectic lattice from TEAPOT, using the full set of magnet and misalignment errors, as well as full space-charge effects. The only corrections included were a rough closed-orbit correction and chromaticity correction. The lattice was tracked for an entire booster cycle, from multi-turn injection through acceleration to the top energy of 4 GeV, approximately 99,000 turns. An initial injection intensity of 4x1Ol2, injected in 25 turns, resulted in a final intensity of 3 . 2 {approx} 1 0a' {approx}t 4 GeV. Results of the tracking, including emittance growth, particle loss, and particle tune distributions are presented.

AHF Booster Tracking with SIMPSONS

International Nuclear Information System (INIS)

Johnson, D.E.; Neri, F.

2002-01-01

The booster lattice for the Advanced Hydrotest Facility at Los Alamos was tracked in 3-D with the program SIMPSONS, using the full, symplectic lattice from TEAPOT, using the full set of magnet and misalignment errors, as well as full space-charge effects. The only corrections included were a rough closed-orbit correction and chromaticity correction. The lattice was tracked for an entire booster cycle, from multi-turn injection through acceleration to the top energy of 4 GeV, approximately 99,000 turns. An initial injection intensity of 4x1Ol2, injected in 25 turns, resulted in a final intensity of 3 . 2 ∼ 1 0a' ∼t 4 GeV. Results of the tracking, including emittance growth, particle loss, and particle tune distributions are presented.

Injection Bucket Jitter Compensation Using Phase Lock System at Fermilab Booster

Energy Technology Data Exchange (ETDEWEB)

Seiya, K. [Fermilab; Drennan, C. [Fermilab; Pellico, W. [Fermilab; Chaurize, S. [Fermilab

2017-05-12

The extraction bucket position in the Fermilab Booster is controlled with a cogging process that involves the comparison of the Booster rf count and the Recycler Ring revolution marker. A one rf bucket jitter in the ex-traction bucket position results from the variability of the process that phase matches the Booster to the Recycler. However, the new slow phase lock process used to lock the frequency and phase of the Booster rf to the Recycler rf has been made digital and programmable and has been modified to correct the extraction notch position. The beam loss at the Recycler injection has been reduced by 20%. Beam studies and the phase lock system will be discussed in this paper.

Logic and control module for the Fermilab booster beam damper

International Nuclear Information System (INIS)

Sandberg, B.R.

1977-01-01

A logic and control module is included in the electronic system of the booster superdamper. This module produces a 9-bit digital word that controls the delay of beam bunch position information in the Fermilab booster synchrotron so that it arrives at the damping electrodes at the same time as the bunch of beam to be corrected. This delay word generator also has an output feature that only allows delay time decreases as the booster synchrotron frequency program increases monotonically. Such a feature guards against low-index incidental FM from affecting the delay computations

Primary and booster vaccination in Latin American children with a DTPw-HBV/Hib combination: a randomized controlled trial.

Science.gov (United States)

Espinoza, Felix; Tregnaghi, Miguel; Gentile, Angela; Abarca, Katia; Casellas, Javier; Collard, Alix; Lefevre, Inge; Jacquet, Jeanne-Marie

2010-10-15

Diphtheria-tetanus-whole-cell pertussis (DTPw)-based combination vaccines are an attractive option to rapidly achieve high coverage and protection against other important pathogens, such as hepatitis B virus (HBV) and Haemophilus influenzae type B (Hib). To ensure adequate antigen supply, GlaxoSmithKline Biologicals has introduced a new DTPw antigen source and developed a new DTPw-HBV/Hib combination vaccine containing a reduced amount of Hib polyribosylribitol phosphate (PRP). This study was undertaken to compare the immunogenicity and reactogenicity of this new DTPw-HBV/Hib vaccine with a licensed DTPw-HBV/Hib vaccine (Tritanrix™-HBV/Hib). This was a randomized, partially-blind, multicenter study in three countries in Latin America (Argentina, Chile and Nicaragua). Healthy children received either the new DTPw-HBV/Hib vaccine (1 of 3 lots; n = 439; double-blind) or Tritanrix™-HBV/Hib (n = 146; single-blind) co-administered with oral poliovirus vaccine (OPV) at 2, 4 and 6 months, with a booster dose at 18-24 months. One month after the end of the 3-dose primary vaccination course, the new DTPw-HBV/Hib vaccine was non-inferior to Tritanrix™-HBV/Hib in terms of seroprotection/vaccine response rates for all component antigens; ≥97.3% and ≥93.9% of subjects in the two groups, respectively, had seroprotective levels of antibodies against diphtheria, tetanus, hepatitis B and Hib and a vaccine response to the pertussis component. Persistence of antibodies against all vaccine antigens was comparable between groups, with marked increases in all antibody concentrations after booster administration in both groups. Both vaccines were generally well-tolerated as primary and booster doses. Results confirm the suitability of this new DTPw-HBV/Hib vaccine comprising antigens from a new source and a reduced PRP content for inclusion into routine childhood vaccination programs. http://www.clinicaltrials.gov NCT00332566.

Booster effect of canine distemper, canine parvovirus infection and infectious canine hepatitis combination vaccine in domesticated adult dogs.

Science.gov (United States)

Taguchi, Masayuki; Namikawa, Kazuhiko; Maruo, Takuya; Orito, Kensuke; Lynch, Jonathan; Tsuchiya, Ryo; Sahara, Hiroeki

2012-08-01

Domesticated adult dogs with antibody titer classified as below 'high' to one or more of canine distemper virus (CDV), canine parvovirus type-2 (CPV-2) and canine adenovirus type-1 (CAdV-1) were then given an additional inoculation, and the effectiveness of this booster evaluated 2 months later. Consequently, CDV and CAdV-1 antibody titer experienced a significant increase, but the same effect was not observed in the antibody titer of CPV-2. These findings suggest that with additional inoculation, a booster effect may be expected in increasing antibody titers for CDV and CAdV-1, but it is unlikely to give an increase in CPV-2 antibody titer. © 2012 The Societies and Blackwell Publishing Asia Pty Ltd.

Identifying strategies to improve the effectiveness of booster seat laws

Science.gov (United States)

2008-05-01

The objective of this project was to identify strategies to improve the effectiveness of booster seat laws. The project explored the possible factors that relate to the use and nonuse of booster seats, and examined the attitudes of law enforcement of...

The Booster to AGS beam transfer fast kicker systems

International Nuclear Information System (INIS)

Zhang, W.; Bunicci, J.; Soukas, A.V.; Zhang, S.Y.

1992-01-01

The Brookhaven AGS Booster has a very successful commissioning period in June 1991. The third phase of that commissioning was a beam extraction test. The Booster extraction fast kicker (F3) deflected a 1.2 GeV proton beam from the Booster circulating orbit into the extraction septum aperture, partially down the extraction line to a temporary beam stop. Now, the Booster is committed to the AGS operations program for both heavy ion and proton beams. Thus, the Booster extraction and the corresponding AGS injection systems must operate routinely up to a pulse repetition frequency of 7.5 Hertz, and up to a beam energy of 1.5 Gev. The injection fast kicker is located in the A5 section of the AGS ring and is used to deflect the proton or heavy ion beam into its final AGS closed orbit. A distinctive feature of the AGS injection fast kicker modulators is the tail-bitting function required for proton beam injection. This enables the system to produce a fast current fall time to go along with the high current pulse amplitude with a fast rise time. The AGS injection fast kicker system has three pulse modulators, and each modulator consists of two thyratrons. The main PFN thyratrons switch on the current, and the tail bitting thyratrons are used to force the magnet current to decrease rapidly. Two digital pulse delay generators are used to align the main thyratrons and the tail bitting thyratrons respectively. The system has been tested and installed. The final commissioning of the Booster to AGS beam transfer line and injection is currently being undertaken. In this article, the system design, realization techniques and performance data will be presented

A rookie's guide to Booster operations. Booster technical note no. 231

Energy Technology Data Exchange (ETDEWEB)

Zeno, K. [Brookhaven National Lab. (BNL), Upton, NY (United States). Alternating Gradient Synchrotron Dept.

1998-09-29

The purpose of the Booster is to act as an injector for the AGS. It accelerates both protons and other ions. Proton acceleration is distinguished from the acceleration of other ions for several reasons. First, the experimental physics associated with protons, called High Energy Physics is different than that associated with other Ions, called Heavy Ion Physics. From the machine perspective, the process of injection of so called Heavy Ions (ions which are not protons), is distinctly different, from that of protons. A different preinjector, or injector for the Booster, is used for each case. For Protons, a 200 MeV Linear accelerator (The Linac) serves as a preinjector; for Heavy Ions, the Tandem Van De Graaf (The Tandem) is the preinjector. An attribute of the circulating beam which determines to a large degree what problems and what type of machine setup is involved is the beam intensity. The author's focus in this guide is on trying to convey the knowledge and experience involved in the operation of the Booster. Many of the problems encountered can be traced back to equipment failures, often power supplies. Although diagnostics are used, there can also be issues with the controls system itself. Problems with the controls system and prevent fixing or even finding a problem with a machine. The issue of improving a machines' performance can often involve trial and error and observations. The hard part is finding the relationships between things in the day to day operation of the machine. Abstractions about physics, information about controls and instrumentation, and purely empirical observations of how the machine behaves are all part of it.

Momentum Cogging at the Fermilab Booster

International Nuclear Information System (INIS)

Seiya, K.; Drennan, C.C.; Pellico, W.; Triplett, A.K.; Waller, A.M.

2012-01-01

The Fermilab Booster has an upgrade plan called the Proton Improvement Plan (PIP). The flux throughput goal is 2E17 protons/hour which, is almost double the present flux, 1.1E17 protons/hour. The beam loss in the machine is going to be an issue. The Booster accelerates beam from 400 MeV to 8 GeV and extracts to the Main Injector (MI). The current cogging process synchronizes the extraction kicker gap to the MI by changing radial position of the beam during the cycle. The gap creation occurs at about 700 MeV, which is about 6 ms into the cycle. The cycle-to-cycle variations of the Booster are larger at lower energy. However, changing the radial position at low energy for cogging is limited because of aperture. Momentum cogging is able to move the gap creation to an earlier time by using dipole correctors and radial position feedback, and is able to control the revolution frequency and radial position at the same time. The new cogging is expected to reduce beam loss and not be limited by aperture. The progress of the momentum cogging system development is going to be discussed in this paper.

FNAL Booster intensity, extraction, and synchronization control for collider operation

International Nuclear Information System (INIS)

Ducar, R.J.; Lackey, J.R.; Tawzer, S.R.

1987-03-01

Booster operation for collider physics is considerably different than for fixed target operation. Various scenarios for collider physics, machine studies, and P-Bar targeting may require that the intensity vary from 5E10 PPP to 3E12 PPP at a 15 Hertz machine cycle rate. In addition to the normal Booster single turn extraction mode, collider operations require that the Booster inject into the Main Ring a small number of beam bunches for coalescing into a single high intensity bunch. These bunches must be synchronized such that the center bunch arrives in the RF bucket which corresponds to the zero phase of the coalescing cavity. The system implemented has the ability to deliver a precise fraction of the available 84 Booster beam bunches to Main Ring or to the P-Bar Debuncher via the newly installed AP-4 beam line for tune-up and studies. It is required that all of the various intensity and extraction scenarios be accommodated with minimal operator intervention

SUCCESS RATE OF ONE SESSION AND TWO SESSION TECHNIQUES FOR TREATMENT OF ASYMPTOMATIC PULPITIS OF PRIMARY TEETH WITH INDIRECT PULP CAPPING.

Directory of Open Access Journals (Sweden)

Rossitza Kabaktchieva

2013-01-01

Full Text Available Objective: Objective: To compare the success rate between the one session and two session indirect pulp capping of asymptomatic pulpitis for 1 year after the treatment was performed in children with different caries risk. Material and Methods: The children and the teeth were selected according to certain criteria for inclusion in the study. According to that, 72 children with low, moderate and high caries risk were included and 131 teeth with asymptomatic pulpitis were treated. The clinical protocols for indirect pulp capping (IPC in one session and two sessions were defined. The review appointments were performed 6 and 12 months after the treatment using certain clinical and radiographic criteria which defined success or post-treatment complications. The results are statistically analysed using One Sided Exact Two-Proportion Test with 95% Significance level (5% risk of type I error. Results: The statistical test showed that between the compared success rates of the one session and two sessions IPC, on the 6th and 12th month, there wasn’t a significant difference (p>0.05. This was valid for every one of the examined groups of patients (p>0. 05. This proves that there is no difference in the success rates of treatment of pulpitis in primary teeth using one or two sessions. Conclusions: The results about the success of treatment of asymptomatic pulpitis in primary teeth during one or two sessions have confirmed the results showed in other current studies. Our study has confirmed (clinically and radiographically the success of both techniques and we have concluded that in children with high caries risk, more appropriate technique is the one performed in two sessions. Treatment in one session is recommended in children with low or moderate caries risk.

Space shuttle with common fuel tank for liquid rocket booster and main engines (supertanker space shuttle)

Science.gov (United States)

Thorpe, Douglas G.

1991-01-01

An operation and schedule enhancement is shown that replaces the four-body cluster (Space Shuttle Orbiter (SSO), external tank, and two solid rocket boosters) with a simpler two-body cluster (SSO and liquid rocket booster/external tank). At staging velocity, the booster unit (liquid-fueled booster engines and vehicle support structure) is jettisoned while the remaining SSO and supertank continues on to orbit. The simpler two-bodied cluster reduces the processing and stack time until SSO mate from 57 days (for the solid rocket booster) to 20 days (for the liquid rocket booster). The areas in which liquid booster systems are superior to solid rocket boosters are discussed. Alternative and future generation vehicles are reviewed to reveal greater performance and operations enhancements with more modifications to the current methods of propulsion design philosophy, e.g., combined cycle engines, and concentric propellant tanks.

Weight Loss Trajectories and Adverse Childhood Experience among Obese Adolescents with Polycystic Ovary Syndrome.

Science.gov (United States)

Rofey, Dana L; El Nokali, Nermeen E; Jackson Foster, Lovie J; Seiler, Emily; McCauley, Heather L; Miller, Elizabeth

2018-03-08

To examine the effect of childhood trauma and family history of psychiatric illness on weight loss trajectories of obese, female adolescents with polycystic ovary syndrome (PCOS). Prospective study. PCOS and adolescent medicine outpatient clinics. Participants were, on average, 15.8 years of age, 80% Caucasian (39/49 participants), and had a body mass index of 36.8 ± 8.8. Healthy Bodies, Healthy Minds is an evidence-based one-on-one intervention consisting of 4 weekly sessions, 4 biweekly sessions, and 3 monthly booster sessions. Each session was 45-60 minutes long with 15-30 minutes of physical activity with a lifestyle coach. Paired sample t tests were used to assess group differences in pre- and post-treatment weight between participants reporting childhood trauma and body mass index-matched controls not endorsing trauma. One-way analysis of variance was performed to assess the influence of childhood trauma on weight loss between the 2 groups. Adolescents without a family history of psychiatric illness lost more weight (mean, -1.28 kg; SD, 6.89) than those who had a family history of psychiatric illness (mean, -0.64 kg; SD, 4.7) from baseline to booster session completion (6 months). However, results of independent t tests did not reveal statistically significant group differences in weight loss from baseline to booster session completion (t 21  = 0.51; P = .6). Obese adolescents with PCOS who have experienced childhood trauma can lose weight and acquire its health benefits when enrolled in an intervention addressing weight, mood, and sleep. Family history of psychiatric illness emerged as a potential predictor of lesser weight loss. Copyright © 2018. Published by Elsevier Inc.

Linac boosters for electrostatic machines

International Nuclear Information System (INIS)

Ben-Zvi, I.; Brookhaven National Lab., Upton, NY

1990-01-01

A survey of linacs which are used as boosters to electrostatic accelerators is presented. Machines both operating and under construction, copper and superconducting, are reviewed. The review includes data on the accelerating structures, performance, rf and control, beam optics, budget, vacuum and cryogenics. (orig.)

Meningococcal serogroup C immunogenicity, antibody persistence and memory B-cells induced by the monovalent meningococcal serogroup C versus quadrivalent meningococcal serogroup ACWY conjugate booster vaccine: A randomized controlled trial.

Science.gov (United States)

van Ravenhorst, Mariëtte B; van der Klis, Fiona R M; van Rooijen, Debbie M; Knol, Mirjam J; Stoof, Susanne P; Sanders, Elisabeth A M; Berbers, Guy A M

2017-08-24

Adolescents are considered the key transmitters of meningococci in the population. Meningococcal serogroup C (MenC) antibody levels wane rapidly after MenC conjugate vaccination in young children, leaving adolescents with low antibody levels. In this study, we compared MenC immune responses after booster vaccination in adolescence with either tetanus toxoid conjugated MenC (MenC-TT) or MenACWY (MenACWY-TT) vaccine, and aimed to establish an optimal age for this booster. Healthy 10-, 12-, and 15-year-olds, who received a single dose of MenC-TT vaccine in early childhood, were randomized to receive MenC-TT or MenACWY-TT vaccine. MenC serum bactericidal antibody (rSBA) titers, MenC polysaccharide (PS) specific IgG, IgG1 and IgG2 and MenC-specific IgG and IgA memory B-cells were determined before, one month and one year after the booster. Non-inferiority was tested by comparing geometric mean titers (GMTs) between vaccinees at one year. Of 501 participants, 464 (92.6%) were included in the 'according to protocol' cohort analysis. At one month, all participants developed high MenC rSBA titers (>24,000 in all groups) and MenC-PS-specific IgG levels. Non-inferiority was not demonstrated one year after the booster with higher MenC GMTs after the monovalent vaccine, but 462/464 (99.6%) participants maintained protective MenC rSBA titers. IgG levels mainly consisted of IgG1, but similar levels of increase were observed for IgG1 and IgG2. Both vaccines induced a clear increase in the number of circulating MenC-PS specific IgG and IgA memory B-cells. Between one month and one year, the highest antibody decay rate was observed in the 10-year-olds. Both MenC-TT and MenACWY-TT vaccines induced robust protective MenC immune responses after the booster vaccination, although non-inferiority could not be demonstrated for the MenACWY-TT vaccine after one year. Our results underline the importance of optimal timing of a meningococcal booster vaccination to protect against MenC disease

JAERI tandem-accelerator and tandem-booster

Energy Technology Data Exchange (ETDEWEB)

Yoshida, Tadashi [Japan Atomic Energy Research Inst., Tokai, Ibaraki (Japan). Tokai Research Establishment

1998-03-01

In 1982, aiming at the new development of atomic energy research, the tandem accelerator of Japan Atomic Energy Research Institute (JAERI) was installed. In fiscal year 1993, the superconducting boosters which can increase the ion energy by up to 4 times were added, and the research in the region below 1000 MeV became possible. Those are electrostatic type accelerators which are easy to be used especially in basic research field, and are useful for future research. The tandem accelerator has been operated while maintaining the first class performance as the accelerator for various kinds of heavy ion beam. It has the special shape among electrostatic type accelerators, and is excellent in the easiness of control and stability. The main particulars of the tandem accelerator are shown. As for the ion sources of the tandem accelerator, three cesium sputter type ion sources are installed on two high voltage stands. The kinds of the ions which can be accelerated are mainly negative ions. As the improvement, electron cyclotron resonance (ECR) ion sources are expected to be adopted. As for the tandem boosters, the 1/4 wavelength type resonance hollow cylinder was adopted. The constitution of the tandem boosters is explained. The way of utilizing the tandem accelerator system and the aim for hereafter are reported. (K.I.)

47 CFR 74.1290 - FM translator and booster station information available on the Internet.

Science.gov (United States)

2010-10-01

... 47 Telecommunication 4 2010-10-01 2010-10-01 false FM translator and booster station information... DISTRIBUTIONAL SERVICES FM Broadcast Translator Stations and FM Broadcast Booster Stations § 74.1290 FM translator and booster station information available on the Internet. The Media Bureau's Audio Division...

78 FR 29062 - Signal Booster Rules

Science.gov (United States)

2013-05-17

... number of FCC rules concerning signal boosters for consumer and industrial use. This document corrects a... chapter; the Maritime Services (ship earth station devices only) pursuant to part 80 of this chapter; and...

Examining How Adding a Booster to a Behavioral Nutrition Intervention Prompts Parents to Pack More Vegetables and Whole Gains in Their Preschool Children's Sack Lunches.

Science.gov (United States)

Sweitzer, Sara J; Ranjit, Nalini; Calloway, Eric E; Hoelscher, Deanna M; Almansor, Fawaz; Briley, Margaret E; Roberts-Gray, Cynthia R

2016-01-01

Data from a five-week intervention to increase parents' packing of vegetables and whole grains in their preschool children's sack lunches showed that, although changes occurred, habit strength was weak. To determine the effects of adding a one-week booster three months post-intervention, children's (N = 59 intervention and 48 control) lunches were observed at baseline (week 0), post-intervention (week 6), pre-booster (week 20), and post-booster (week 26). Servings of vegetables and whole grains were evaluated in repeated measures models and results inspected relative to patterns projected from different explanatory models of behavior change processes. Observed changes aligned with projections from the simple associative model of behavior change. Attention in future studies should focus on behavioral intervention elements that leverage stimulus-response associations to increase gratification parents receive from providing their children with healthy lunches.

The AGS Booster Beam Position Monitor system

International Nuclear Information System (INIS)

Ciardullo, D.J.; Abola, A.; Beadle, E.R.; Smith, G.A.; Thomas, R.; Van Zwienen, W.; Warkentien, R.; Witkover, R.L.

1991-01-01

To accelerate both protons and heavy ions, the AGS Booster requires a broadband (multi-octave) beam position monitoring system with a dynamic range spanning several orders of magnitude (2 x 10 10 to 1.5 x 10 13 particles per pulse). System requirements include the ability to acquire single turn trajectory and average orbit information with ± 0.1 mm resolution. The design goal of ± 0.5 mm corrected accuracy requires that the detectors have repeatable linear performance after periodic bakeout at 300 degree C. The system design and capabilities of the Booster Beam Position Monitor will be described, and initial results presented. 7 refs., 5 figs

Advanced Booster Composite Case/Polybenzimidazole Nitrile Butadiene Rubber Insulation Development

Science.gov (United States)

Gentz, Steve; Taylor, Robert; Nettles, Mindy

2015-01-01

The NASA Engineering and Safety Center (NESC) was requested to examine processing sensitivities (e.g., cure temperature control/variance, debonds, density variations) of polybenzimidazole nitrile butadiene rubber (PBI-NBR) insulation, case fiber, and resin systems and to evaluate nondestructive evaluation (NDE) and damage tolerance methods/models required to support human-rated composite motor cases. The proposed use of composite motor cases in Blocks IA and II was expected to increase performance capability through optimizing operating pressure and increasing propellant mass fraction. This assessment was to support the evaluation of risk reduction for large booster component development/fabrication, NDE of low mass-to-strength ratio material structures, and solid booster propellant formulation as requested in the Space Launch System NASA Research Announcement for Advanced Booster Engineering Demonstration and/or Risk Reduction. Composite case materials and high-energy propellants represent an enabling capability in the Agency's ability to provide affordable, high-performing advanced booster concepts. The NESC team was requested to provide an assessment of co- and multiple-cure processing of composite case and PBI-NBR insulation materials and evaluation of high-energy propellant formulations.

Frequency of booster injections of allergoids.

Science.gov (United States)

Norman, P S; Creticos, P S; Marsh, D G

1990-01-01

In 1982, 43 ragweed-sensitive patients receiving maintenance injections of full doses of ragweed allergoid were selected for a study of the immunologic and clinical efficacy of booster injections only four times a year. These patients had participated for 2 to 7 years as part of a trial of mixes of up to four allergoids to common pollens in the mid-Atlantic area tailored to each patient's skin test sensitivity. They were divided into a group (21 patients) to receive injections every 3 months and a group (22 patients) to receive injections about every 6 weeks (eight injections per year). Patients were rerandomized after 1 year so that half of each original group switched to the alternate treatment, and this program was continued until after the ragweed season of 1985. Thirty-four patients were still under study the last year. Doses, per injection, were 100 allergoid units (1 allergoid unit equals 100 PNU) of each allergen in the mixture. Symptom scores during the 8 weeks of each of the four ragweed seasons were not significantly higher in the 3-month treated group. IgG antibody levels to Amb a I (antigen E) were followed until early 1984 and were not significantly different in the two groups, even though the 6-week treated patients received a two times higher cumulative dose per year. Rates of local and systemic reactions (percent of injections eliciting reactions) were not different in the groups, which means that the 3-month treated group had about half as many reactions by virtue of taking half as many injections.(ABSTRACT TRUNCATED AT 250 WORDS)

MEASUREMENTS AND MODELING OF EDDY CURRENT EFFECTS IN BNL'S AGS BOOSTER

International Nuclear Information System (INIS)

BROWN, K.A.; AHRENS, L.; GARDNER, C.; GLENN, J.W.; HARVEY, M.; MENG, W.; ZENO, K.

2006-01-01

Recent beam experiments at BNL's AGS Booster have enabled us to study in more detail the effects of eddy currents on the lattice structure and our control over the betatron tune. The Booster is capable of operating at ramp rates as high as 9 T/sec. At these ramp rates eddy currents in the vacuum chambers significantly alter the fields and gradients seen by the beam as it is accelerated. The Booster was designed with these effects in mind and to help control the field uniformity and linearity in the Booster Dipoles special vacuum chambers were designed with current windings to negate the affect of the induced eddy currents. In this report results from betatron tune measurements and eddy current simulations will be presented. We will then present results from modeling the accelerator using the results of the magnetic field simulations and compare these to the measurements

Tdap Booster Requirements for Secondary Schools

Science.gov (United States)

... Experts State Information Tdap booster requirements for secondary schools State Td or Tdap Mandate for Sec School ... Checklists Standing Orders Storage & Handling Talking with Parents Temperature Logs Top Handouts Translations Vaccine Index >> view all ...

Tracking study of hadron collider boosters

Energy Technology Data Exchange (ETDEWEB)

Machida, S.; Bourianoff, G.; Huang, Y.; Mahale, N.

1992-07-01

A simulation code SIMPSONS (previously called 6D-TEASE T) of single- and multi-particle tracking has been developed for proton synchrotrons. The 6D phase space coordinates are calculated each time step including acceleration with an arbitrary ramping curve by integration of the rf phase. Space-charge effects are modelled by means of the Particle In Cell (PIC) method. We observed the transverse emittance growth around the injection energy of the Low Energy Booster (LEB) of the Superconducting Super Collider (SSC) with and without second harmonic rf cavities which reduce peak line density. We also employed the code to see the possible transverse emittance deterioration around the transition energy in the Medium Energy Booster (MEB) and to estimate the emittance dilution due to an injection error of the MEB.

Injection and transfer lines of the PS Booster

CERN Multimedia

Photographic Service

1972-01-01

In the foreground is the vacuum chamber for the 50 MeV proton beam coming from the Linac. The tank held by white frames houses the "Vertical Distributor", which deflects the Linac beam to the levels of the Booster's 4 superposed rings. After acceleration in the Booster, originally to 800 MeV, today to 1.4 GeV, the beams from the 4 rings are combined in the vertical plane and transfered to the 26 GeV PS. The "Recombination Line", intersecting the injection line, crosses the picture from left to right.

Design study of CEPC Alternating Magnetic Field Booster

CERN Document Server

Bian, T; Cai, Y; Cui, X; Gao, J; Koratzinos, M; Su, F; Wang, D; Wang, Y; Xiao, M; Zhang, C

2017-01-01

The CEPC is a next generation circular e+e- collider proposed by China. The design of the full energy booster ring of the CEPC is especially challenging. The ejected beam energy is 120 GeV, but that of the injected beam is only 6 GeV. In a conventional approach, the low magnetic field of the main dipole magnets creates problems. We propose operating the booster ring as a large wiggler at low beam energies and as a normal ring at high energies to avoid the problem of very low dipole magnet fields.

Assessment of immunogenicity and safety following primary and booster immunisation with a CRM197 -conjugated Haemophilus influenzae type B vaccine in healthy Chinese infants.

Science.gov (United States)

Jun, L; Yuguo, C; Zhiguo, W; Jinfeng, L; Huawei, M; Xiuhua, L; Yonggui, Z; Yanhua, X; Kong, Y; Hongtao, L; Yuliang, Z

2013-10-01

Invasive meningitis and pneumonia caused by Haemophilus influenzae type b (Hib) is an important cause of childhood mortality in countries where Hib vaccination is not routine. We evaluated the non-inferiority of a licensed Hib vaccine, PRP-CRM(197) compared with a second licensed Hib vaccine, PRP-T, following the recommended Chinese immunisation schedule for infants between 6 months and 1 year of age. In the first study phase, 6-12 month-old infants received two primary doses of either PRP-CRM(197) (n = 335) or PRP-T (n = 335) vaccine administered 1 month apart. In the second study phase 8 months later, the same children received a single booster dose of vaccine identical to that use for priming (PRP-CRM(197), n = 327; PRP-T, n = 333). Serum levels of anti-polyribosylribitol phosphate (PRP) antibodies were measured using enzyme-linked immunosorbent assay (ELISA). Non-inferiority of primary and booster doses was assessed in terms of percentages of subjects with anti-PRP antibody levels associated with providing short-term (≥ 0.15 μg/ml) and long-term (≥ 1.0 μg/ml) protection; the non-inferiority margin was set at -5%. PRP-CRM(197) was demonstrated to be non-inferior to PRP-T. Anti-PRP antibodies levels ≥ 0.15 μg/ml and ≥ 1.0 μg/ml were achieved by 97% of infants in the PRP-CRM(197) group and 98% of infants in the PRP-T group 1 month after primary immunisation, and by all subjects (100%) in both vaccine groups 1 month after booster administration. Safety profiles for both vaccines were similar; no serious adverse events, deaths or adverse events leading to withdrawal occurred during the study. PRP-CRM(197) was well-tolerated and immunologically non-inferior to a licensed comparator Hib vaccine in Chinese infants (Clinicaltrials.gov: NCT01044316 & NCT01226953). © 2013 John Wiley & Sons Ltd.

Primary and booster vaccination in Latin American children with a DTPw-HBV/Hib combination: a randomized controlled trial

Directory of Open Access Journals (Sweden)

Collard Alix

2010-10-01

Full Text Available Abstract Background Diphtheria-tetanus-whole-cell pertussis (DTPw-based combination vaccines are an attractive option to rapidly achieve high coverage and protection against other important pathogens, such as hepatitis B virus (HBV and Haemophilus influenzae type B (Hib. To ensure adequate antigen supply, GlaxoSmithKline Biologicals has introduced a new DTPw antigen source and developed a new DTPw-HBV/Hib combination vaccine containing a reduced amount of Hib polyribosylribitol phosphate (PRP. This study was undertaken to compare the immunogenicity and reactogenicity of this new DTPw-HBV/Hib vaccine with a licensed DTPw-HBV/Hib vaccine (Tritanrix™-HBV/Hib. Methods This was a randomized, partially-blind, multicenter study in three countries in Latin America (Argentina, Chile and Nicaragua. Healthy children received either the new DTPw-HBV/Hib vaccine (1 of 3 lots; n = 439; double-blind or Tritanrix™-HBV/Hib (n = 146; single-blind co-administered with oral poliovirus vaccine (OPV at 2, 4 and 6 months, with a booster dose at 18-24 months. Results One month after the end of the 3-dose primary vaccination course, the new DTPw-HBV/Hib vaccine was non-inferior to Tritanrix™-HBV/Hib in terms of seroprotection/vaccine response rates for all component antigens; ≥97.3% and ≥93.9% of subjects in the two groups, respectively, had seroprotective levels of antibodies against diphtheria, tetanus, hepatitis B and Hib and a vaccine response to the pertussis component. Persistence of antibodies against all vaccine antigens was comparable between groups, with marked increases in all antibody concentrations after booster administration in both groups. Both vaccines were generally well-tolerated as primary and booster doses. Conclusions Results confirm the suitability of this new DTPw-HBV/Hib vaccine comprising antigens from a new source and a reduced PRP content for inclusion into routine childhood vaccination programs. Trial registration http

Primary and booster vaccination with DTPw-HB/Hib pentavalent vaccine in Costa Rican children who had received a birth dose of hepatitis B vaccine

Directory of Open Access Journals (Sweden)

Idis Faingezicht

2002-10-01

Full Text Available Objective. The DTPw-HB/Hib pentavalent combination vaccine has been developed following recommendations of the World Health Organization for the introduction of hepatitis B (HB and Haemophilus influenzae type b (Hib vaccines into routine childhood vaccination programs. The objectives of this study were to: 1 analyze the immunogenicity and the reactogenicity of the DTPw-HB/Hib pentavalent combination vaccine in comparison to separate injections of DTPw-HB and Hib vaccines as primary vaccination in a group of children who had received a dose of HB vaccine at birth and 2 in the second year of life to assess the antibody persistence as well as the response to a DTPw-HB/Hib or DTPw/Hib booster. Methods. In the first part of the study (primary-vaccination stage, conducted in 1998-1999, we analyzed the immunogenicity and reactogenicity of the DTPw-HB/Hib combination vaccine in comparison to separate injections of DTPw-HB and Hib vaccines as primary vaccination at 2, 4, and 6 months of age in 207 Costa Rican children who had received a dose of HB vaccine at birth. Later, in the booster-vaccination stage of the study, in 1999-2000, in a subset of the children (69 toddlers, now 15-18 months old, antibody persistence was measured, and response to a DTPw-HB/Hib or DTPw/Hib booster was also assessed. Results. In both primary-vaccination groups, at least 97.5% of the infants reached protective levels of antibodies (seropositivity against the antigens employed in the vaccines. The DTPw-HB/Hib pentavalent combination vaccine did not result in more local reactions than did the DTPw-HB vaccine alone, and, in terms of general reactions, there was no clinically significant difference between the combination or separate injections, and with the pentavalent vaccine having the benefit of needing one less injection. Nine months after the third dose of the primary-vaccination course, antibody persistence was similar in both groups, with over 93% of children still having

Emittance measurement and modeling for the Fermilab Booster

Directory of Open Access Journals (Sweden)

Xiaobiao Huang

2006-01-01

Full Text Available Turn-by-turn beam profile data measured at the Fermilab Booster are studied. Lattice models with experimental accelerator ramping parameters are used to obtain the lattice functions for data analysis. We studied the horizontal and vertical emittance growth behavior in different stages of a booster ramping cycle and its relation to the beam intensity. The transverse and longitudinal components in the horizontal beam width are separated by a fitting model which makes use of the different scaling rules of the beam momentum. We analyze the post-transition horizontal beam size oscillation based on a model where the longitudinal phase-space mismatch has resulted from rf voltage mismatch during the transition-energy crossing. We carried out systematic multiparticle simulation to show that the source of the vertical emittance growth is a combination of the random errors in skew-quadrupole and dipole fields, and the systematic Montague resonance. The effect of random quadrupole field is small for the Fermilab Booster because the betatron envelope tunes are reasonably far away from the half-integer stop band.

Long-term persistence in protection and response to a hepatitis B vaccine booster among adolescents immunized in infancy in the western region of China.

Science.gov (United States)

Wang, Zhen-Zi; Gao, Yu-Hua; Lu, Wei; Jin, Cun-Duo; Zeng, Ying; Yan, Ling; Ding, Feng; Li, Tong; Liu, Xue-En; Zhuang, Hui

2017-04-03

To evaluate the persistence of protection from hepatitis B (HB) vaccination among adolescents immunized with a primary series of HB vaccine as infants, and the immune response to booster doses. Healthy adolescents aged 15-17 y vaccinated with HB vaccine only at birth were enrolled. Baseline serum hepatitis B surface antigen (HBsAg), antibody against hepatitis B surface antigen (anti-HBs) and antibody against hepatitis B core antigen (anti-HBc) were detected by Enzyme-Linked Immunosorbent Assay (ELISA) and anti-HBs level was measured using Chemiluminescent Microparticle Immunoassay (CMIA). The rate of HBV infection was calculated. The seroprotection rate of anti-HBs (≥ 10 mIU/ml) and GMC level were used to evaluate the persistence of immunity from HB vaccination. Those with anti-HBs infants, 3 (1.7%) had HBV infection and 74 (41.1%) had anti-HBs ≥ 10 mIU/ml with a GMC of 145.11 mIU/ml. The remaining 103 (57.2%) with anti-HBs < 10 mIU/ml received a booster dose of 20 μg HB vaccine and achieved the seroprotection rate of 84% (84/100) and a GMC of 875.19 mIU/ml at one month post-booster. An additional dose of 60 μg HB vaccine was administered to the 16 adolescents with anti-HBs < 10 mIU/ml after the first booster. All of them obtained anti-HBs seroprotection with a GMC of 271.02 mIU/ml at 1.5 months after an additional dose. Vaccine-induced immunity persisted for up to 15-17 y in 89.3% (158/177) of participants after a primary HB vaccination in infancy. Administering a booster dose of 20μg HB vaccine elicited an anamnestic immune responses in the majority of individuals with baseline anti-HBs <10 mIU/ml.

76 FR 11680 - Digital Low Power Television, Television Translator, and Television Booster Stations and Digital...

Science.gov (United States)

2011-03-03

...] Digital Low Power Television, Television Translator, and Television Booster Stations and Digital Class A... Commission's Rules to Establish Rules for Digital Low Power, Television Translator, and Television Booster... Digital Low Power Television Translator, Television Booster Stations, and to Amend Rules for Digital Class...

NASA's Space Launch System: Developing the World's Most Powerful Solid Booster

Science.gov (United States)

Priskos, Alex

2016-01-01

NASA's Journey to Mars has begun. Indicative of that challenge, this will be a multi-decadal effort requiring the development of technology, operational capability, and experience. The first steps are under way with more than 15 years of continuous human operations aboard the International Space Station (ISS) and development of commercial cargo and crew transportation capabilities. NASA is making progress on the transportation required for deep space exploration - the Orion crew spacecraft and the Space Launch System (SLS) heavy-lift rocket that will launch Orion and large components such as in-space stages, habitat modules, landers, and other hardware necessary for deep-space operations. SLS is a key enabling capability and is designed to evolve with mission requirements. The initial configuration of SLS - Block 1 - will be capable of launching more than 70 metric tons (t) of payload into low Earth orbit, greater mass than any other launch vehicle in existence. By enhancing the propulsion elements and larger payload fairings, future SLS variants will launch 130 t into space, an unprecedented capability that simplifies hardware design and in-space operations, reduces travel times, and enhances the odds of mission success. SLS will be powered by four liquid fuel RS-25 engines and two solid propellant five-segment boosters, both based on space shuttle technologies. This paper will focus on development of the booster, which will provide more than 75 percent of total vehicle thrust at liftoff. Each booster is more than 17 stories tall, 3.6 meters (m) in diameter and weighs 725,000 kilograms (kg). While the SLS booster appears similar to the shuttle booster, it incorporates several changes. The additional propellant segment provides additional booster performance. Parachutes and other hardware associated with recovery operations have been deleted and the booster designated as expendable for affordability reasons. The new motor incorporates new avionics, new propellant

Beam Based RF Voltage Measurements and Longitudinal Beam Tomography at the Fermilab Booster

Energy Technology Data Exchange (ETDEWEB)

Bhat, C. M. [Fermilab; Bhat, S. [Fermilab

2017-10-19

Increasing proton beam power on neutrino production targets is one of the major goals of the Fermilab long term accelerator programs. In this effort, the Fermilab 8 GeV Booster synchrotron plays a critical role for at least the next two decades. Therefore, understanding the Booster in great detail is important as we continue to improve its performance. For example, it is important to know accurately the available RF power in the Booster by carrying out beam-based measurements in order to specify the needed upgrades to the Booster RF system. Since the Booster magnetic field is changing continuously measuring/calibrating the RF voltage is not a trivial task. Here, we present a beam based method for the RF voltage measurements. Data analysis is carried out using computer programs developed in Python and MATLAB. The method presented here is applicable to any RCS which do not have flat-bottom and flat-top in the acceleration magnetic ramps. We have also carried out longitudinal beam tomography at injection and extraction energies with the data used for RF voltage measurements. Beam based RF voltage measurements and beam tomography were never done before for the Fermilab Booster. The results from these investigations will be very useful in future intensity upgrades.

"Booster" training: evaluation of instructor-led bedside cardiopulmonary resuscitation skill training and automated corrective feedback to improve cardiopulmonary resuscitation compliance of Pediatric Basic Life Support providers during simulated cardiac arrest.

Science.gov (United States)

Sutton, Robert M; Niles, Dana; Meaney, Peter A; Aplenc, Richard; French, Benjamin; Abella, Benjamin S; Lengetti, Evelyn L; Berg, Robert A; Helfaer, Mark A; Nadkarni, Vinay

2011-05-01

To investigate the effectiveness of brief bedside "booster" cardiopulmonary resuscitation (CPR) training to improve CPR guideline compliance of hospital-based pediatric providers. Prospective, randomized trial. General pediatric wards at Children's Hospital of Philadelphia. Sixty-nine Basic Life Support-certified hospital-based providers. CPR recording/feedback defibrillators were used to evaluate CPR quality during simulated pediatric arrest. After a 60-sec pretraining CPR evaluation, subjects were randomly assigned to one of three instructional/feedback methods to be used during CPR booster training sessions. All sessions (training/CPR manikin practice) were of equal duration (2 mins) and differed only in the method of corrective feedback given to participants during the session. The study arms were as follows: 1) instructor-only training; 2) automated defibrillator feedback only; and 3) instructor training combined with automated feedback. Before instruction, 57% of the care providers performed compressions within guideline rate recommendations (rate >90 min(-1) and 38 mm); and 36% met overall CPR compliance (rate and depth within targets). After instruction, guideline compliance improved (instructor-only training: rate 52% to 87% [p .01], and overall CPR compliance, 43% to 78% [p CPR compliance, 35% to 96% [p training combined with automated feedback: rate 48% to 100% [p CPR compliance, 30% to 100% [p CPR instruction, most certified Pediatric Basic Life Support providers did not perform guideline-compliant CPR. After a brief bedside training, CPR quality improved irrespective of training content (instructor vs. automated feedback). Future studies should investigate bedside training to improve CPR quality during actual pediatric cardiac arrests.

"Booster" interventions to sustain increases in physical activity in middle-aged adults in deprived urban neighbourhoods: internal pilot and feasibility study

Directory of Open Access Journals (Sweden)

Walters Stephen J

2011-02-01

Full Text Available Abstract Background Systematic reviews have identified a range of brief interventions which increase physical activity in previously sedentary people. A randomised controlled trial is needed to assess whether providing motivational interviewing, three months after giving initial advice, sustains physical activity levels in those who recently became physically active. This paper reports the results of an internal pilot study designed to test the feasibility of the study in terms of recruitment, per protocol delivery of the intervention and retention at three months. Methods Participants were: aged 40-64 years; resident in deprived areas of Sheffield, UK; and, had recently become physically active as a result of using a brief intervention following an invitation from a mass mailout. Interventions: Motivational Interviewing 'boosters' aimed at sustaining change in physical activity status delivered face-to-face or over the telephone compared with no further intervention. Outcomes of the feasibility study: recruitment of 60 participants from mailout of 3,300; retention of 45 participants with 3-month follow-up accelerometry measurements; 70% of those randomised to boosters receiving intervention per protocol. Sample size and power were recalculated using the accelerometry data collected. Results Forty-seven participants were randomised (78% of the feasibility target; 37 participants were retained at three months, 29 with at least four days of accelerometry data (64% of the feasibility target; 79% of those allocated boosters received them per protocol (surpassing the feasibility target. The proposed sample size of 600 was confirmed as appropriate and power is expected to be sufficient to detect a difference between groups. Conclusions The main study will continue with the original recruitment target of 600 participants but to ensure feasibility, it is necessary to increase recruitment and improve the numbers of those followed-up who have evaluable

Immunogenicity and safety of combined adsorbed low-dose diphtheria, tetanus and inactivated poliovirus vaccine (REVAXIS®) versus combined diphtheria, tetanus and inactivated poliovirus vaccine (DT Polio®) given as a booster dose at 6 years of age

Science.gov (United States)

Gajdos, Vincent; Soubeyrand, Benoit; Vidor, Emmanuel; Richard, Patrick; Boyer, Julie; Sadorge, Christine

2011-01-01

This randomized, comparative, phase-IIIb study conducted in France aimed to demonstrate whether seroprotection against diphtheria, tetanus and poliomyelitis 1 month after a single dose of REVAXIS (low-dose diphtheria) is non-inferior to seroprotection 1 month after a single dose of DT Polio (standard-dose diphtheria), both vaccines being given as a second booster to healthy children at 6 years of age. Children were randomly assigned to receive a single intramuscular dose of REVAXIS or DT Polio. Primary endpoints were the 1-month post-booster seroprotection rates for diphtheria, tetanus and poliovirus type-1, -2 and -3 antigens. Secondary endpoints were immunogenicity and safety observations. Of 788 children screened, 760 were randomized: REVAXIS group, 384 children; DT Polio group, 376 children. No relevant difference in demographic characteristics at baseline was observed between REVAXIS and DT Polio groups. Noninferiority of REVAXIS compared with DT Polio for seroprotection was demonstrated against diphtheria (respectively 98.6% and 99.3%), tetanus (respectively 99.6% and 100%) and poliovirus antigens (100% for each types in both groups). No allergic reactions to REVAXIS were reported. A benefit/risk ratio in favor of REVAXIS was suggested by the trend towards a better tolerability of REVAXIS compared with DT Polio regarding the rate of severe solicited injection-site reactions. The results support the use of REVAXIS as a booster at 6 years of age in infants who previously received a three-dose primary series within the first 6 months of life and a first booster including diphtheria, tetanus and poliovirus vaccine(s) given before 2 years of age. PMID:21441781

Skipping one or more dialysis sessions significantly increases mortality: measuring the impact of non-adherence

Directory of Open Access Journals (Sweden)

Eduardo Gottlieb

2014-06-01

Full Text Available Introduction: Non-adherence to the prescribed dialysis sessions frequency ranges from 2% to 50% of patients. The objective of this study was to evaluate the impact of detecting and measuring the non-adherence to the prescribed dialysis frequency and to determine the importance of a multidisciplinary approach with the aim of improving adherence. Methods: longitudinal cohort study including 8,164 prevalent hemodialysis patients in April 2010, with more than 90 days of treatment, in Fresenius Medical Care Argentina units that were monitored for 3 years. The survey evaluated: interruption of at least one dialysis session in a month or reduction at least 10 minutes of a dialysis session in a month, during 6 months prior to the survey. Relative mortality risks were evaluated among groups. Results: 648 patients (7.9% interrupted dialysis sessions: 320 (3.9% interrupted one session per month and 328 (4.01% interrupted more than one session per month. After 3 years monitoring, 349 patients (53.8 % remained active in hemodialysis and 299 were inactive due to different reasons: 206 deceased (31.8 %, 47 transfers or monitoring losses (7.25 %, 36 transplanted (5.55 %, 8 changes to PD modality (1.2% and 2 recovered their kidney function (0.3 %.Interrupting one session per month significantly increased the mortality risk comparing both groups (interrupters and non-interrupters: RR 2.65 (IC 95% 2.24 – 3.14. Interrupting more than one dialysis session also increased significantly mortality risk comparing to the non-interrupters: RR 2.8 (IC 95% 2.39 – 3.28. After 3 years monitoring, 41.6 % of interrupters at the beginning had improved their adherence through a multidisciplinary program of quality improvement. Conclusion: Global mortality was greater among patients who interrupted dialysis sessions. A considerable proportion of interrupter patients at the beginning modified their behavior through the implementation of a multidisciplinary program of quality

Thermoeconomic model of a commercial transcritical booster refrigeration system

DEFF Research Database (Denmark)

Ommen, Torben Schmidt; Elmegaard, Brian

2011-01-01

For cooling applications in supermarkets, booster refrigeration systems operating in both transcritical and subcritical conditions are increasingly used. A thermodynamic model of a transcritical booster refrigeration plant is tailored to match the new generation of commercial refrigeration plants...... of exergy for cooling. Second law analysis is needed to illustrate the characteristics of the plant at different load rates, according to the alternating load profile and corresponding to outdoor conditions. With the detailed model, different uses of the analysis are possible, including thermoeconomic...

Long-term persistence of immunity and B-cell memory following Haemophilus influenzae type B conjugate vaccination in early childhood and response to booster.

Science.gov (United States)

Perrett, K P; John, T M; Jin, C; Kibwana, E; Yu, L-M; Curtis, N; Pollard, A J

2014-04-01

Protection against Haemophilus influenzae type b (Hib), a rapidly invading encapsulated bacteria, is dependent on maintenance of an adequate level of serum antibody through early childhood. In many countries, Hib vaccine booster doses have been implemented after infant immunization to sustain immunity. We investigated the long-term persistence of antibody and immunological memory in primary-school children following infant (with or without booster) Hib vaccination. Anti-polyribosylribitol phosphate (PRP) immunoglobulin G (IgG) concentration and the frequency of circulating Hib-specific memory B cells were measured before a booster of a Hib-serogroup C meningococcal (MenC) conjugate vaccine and again 1 week, 1 month, and 1 year after the booster in 250 healthy children aged 6-12 years in an open-label phase 4 clinical study. Six to 12 years following infant priming with 3 doses of Hib conjugate vaccine, anti-PRP IgG geometric mean concentrations were 3.11 µg/mL and 0.71 µg/mL and proportions with anti-PRP IgG ≥1.0 µg/mL were 79% and 43% in children who had or had not, respectively, received a fourth Hib conjugate vaccine dose (mean age, 3.9 years). Higher baseline and post-Hib-MenC booster responses (anti-PRP IgG and memory B cells) were found in younger children and in those who had received a fourth Hib dose. Sustained Hib conjugate vaccine-induced immunity in children is dependent on time since infant priming and receipt of a booster. Understanding the relationship between humoral and cellular immunity following immunization with conjugate vaccines may direct vaccine design and boosting strategies to sustain individual and population immunity against encapsulated bacteria in early childhood. Clinical Trials Registration ISRCTN728588998.

Numerically controlled oscillator for the Fermilab Booster

International Nuclear Information System (INIS)

Crisp, J.L.; Ducar, R.J.

1989-01-01

In order to improve the stability of the Fermilab Booster low level rf system, a numerically controlled oscillator system is being constructed. Although the system has not been implemented to date, the design is outlined in this paper. The heart of the new system consists of a numerically synthesized frequency generator manufactured by the Sciteq Company. The 3 GHz/sec rate and 30 to 53 MHz range of the Booster frequency program required the design of a CAMAC based, fast-cycling (1 MHz), 65K x 32 bit, digital function generator. A 1 MHz digital adder and 12 bit analog to digital converter will be used to correct small program errors by phase locking the oscillator to the beam. 6 refs., 1 fig

The operational status of the Booster injector for the AGS accelerator complex at BNL

International Nuclear Information System (INIS)

Ahrens, L.; Bleser, E.; Brennan, J.M.; Gardner, C.; Gill, E.; Glenn, J.W.; Reece, K.; Roser, T.; van Asselt, W.; Weng, W.T.

1992-01-01

The Booster synchrotron at Brookhaven National Laboratory has been incorporated into the accelerator chain at the Alternating Gradient Synchrotron (AGS) complex. After a successful first commissioning effort in the spring of 1991, the Booster has been part of this year's silicon, gold and proton physics runs. After a brief review of the Booster design goals, and of the early commissioning, this paper will summarize this year's activities

GRYPHON: Air launched space booster

Science.gov (United States)

1993-06-01

The project chosen for the winter semester Aero 483 class was the design of a next generation Air Launched Space Booster. Based on Orbital Sciences Corporation's Pegasus concept, the goal of Aero 483 was to design a 500,000 pound air launched space booster capable of delivering 17,000 pounds of payload to Low Earth Orbit and 8,000 pounds of payload to Geosynchronous Earth Orbit. The resulting launch vehicle was named the Gryphon. The class of forty senior aerospace engineering students was broken down into eight interdependent groups. Each group was assigned a subsystem or responsibility which then became their field of specialization. Spacecraft Integration was responsible for ensuring compatibility between subsystems. This group kept up to date on subsystem redesigns and informed those parties affected by the changes, monitored the vehicle's overall weight and dimensions, and calculated the mass properties of the booster. This group also performed the cost/profitability analysis of the Gryphon and obtained cost data for competing launch systems. The Mission Analysis Group was assigned the task of determining proper orbits, calculating the vehicle's flight trajectory for those orbits, and determining the aerodynamic characteristics of the vehicle. The Propulsion Group chose the engines that were best suited to the mission. This group also set the staging configurations for those engines and designed the tanks and fuel feed system. The commercial satellite market, dimensions and weights of typical satellites, and method of deploying satellites was determined by the Payloads Group. In addition, Payloads identified possible resupply packages for Space Station Freedom and identified those packages that were compatible with the Gryphon. The guidance, navigation, and control subsystems were designed by the Mission Control Group. This group identified required tracking hardware, communications hardware telemetry systems, and ground sites for the location of the Gryphon

Fiber optics in the BNL Booster radiation environment

International Nuclear Information System (INIS)

Beadle, E.R.

1991-01-01

The Booster instrumentation uses analog and digital fiber optic links, designed to withstand at least 50 krads without performance degradation. The links use inexpensive and commercially available components that operate at a center wavelength of 820 nm. The analog link operates to 30 MHz over a 200 m fiber and can provide insertion gain. The digital link provides 60 ns timing pulses without the dispersive effects of coaxial cables. The optical fiber is a step-index hard clad silica type with a 200 micron core. This paper presents the component selection criteria, link design, installation, testing and performance for the optical links in the Booster instrumentation systems

Misuse of booster cushions among children and adults in Shanghai-an observational and attitude study during buckling up.

Science.gov (United States)

Bohman, Katarina; Jorlöv, Sofia; Zhou, Shengqi; Zhao, Cloud; Sui, Bo; Ding, Chengkai

2016-10-02

Traffic crashes are one of the leading causes of fatalities among Chinese children. Booster cushion usage in China is low, and there are no studies showing how a population with limited experience handles booster cushions during buckling up. The purpose of this study was to evaluate the handling of and explore the attitudes toward booster cushions among children, parents, and grandparents in Shanghai. An observational study including a convenience sample of 254 children aged 4-12 years was conducted in 2 passenger cars at a shopping center in Shanghai. Parents, grandparents, or the children themselves buckled up the child on 2 types of booster cushions, a 2-stage integrated booster cushion (IBC) and an aftermarket booster cushion (BC). The test participants were observed during buckling up, first without and then with instructions. The test leaders conducted structured interviews. Ninety-eight percent of the uninstructed participants failed to buckle up without identified misuse on the aftermarket booster cushion and 31% of those uninstructed on the integrated booster cushion. The majority of misuse was severe, including placing the belt behind the arm and the lap belt routing above the guiding loops. Instruction reduced misuse to 58% (BC) and 12% (IBC), respectively, and, in particular, severe misuse. Some misuse was related to limited knowledge of how to buckle up on the booster cushion, and some misuse was intentional in order to reduce discomfort. The participants, both children and adults, reported that they preferred the IBC due to good comfort and convenience. Safety was reported as the main reason for adults using booster cushions in general, whereas children reported comfort as the most important motivation. Education is needed to ensure frequent and correct use of booster cushions in China and to raise safety awareness among children and adults. Furthermore, it is important that the booster cushions offer intuitively correct usage to a population with

YALINA Booster subcritical assembly modeling and analyses

International Nuclear Information System (INIS)

Talamo, A.; Gohar, Y.; Aliberti, G.; Cao, Y.; Zhong, Z.; Kiyavitskaya, H.; Bournos, V.; Fokov, Y.; Routkovskaya, C.; Sadovich, S.

2010-01-01

Full text: Accurate simulation models of the YALINA Booster assembly of the Joint Institute for Power and Nuclear Research (JIPNR)-Sosny, Belarus have been developed by Argonne National Laboratory (ANL) of the USA. YALINA-Booster has coupled zones operating with fast and thermal neutron spectra, which requires a special attention in the modelling process. Three different uranium enrichments of 90%, 36% or 21% were used in the fast zone and 10% uranium enrichment was used in the thermal zone. Two of the most advanced Monte Carlo computer programs have been utilized for the ANL analyses: MCNP of the Los Alamos National Laboratory and MONK of the British Nuclear Fuel Limited and SERCO Assurance. The developed geometrical models for both computer programs modelled all the details of the YALINA Booster facility as described in the technical specifications defined in the International Atomic Energy Agency (IAEA) report without any geometrical approximation or material homogenization. Materials impurities and the measured material densities have been used in the models. The obtained results for the neutron multiplication factors calculated in criticality mode (keff) and in source mode (ksrc) with an external neutron source from the two Monte Carlo programs are very similar. Different external neutron sources have been investigated including californium, deuterium-deuterium (D-D), and deuterium-tritium (D-T) neutron sources. The spatial neutron flux profiles and the neutron spectra in the experimental channels were calculated. In addition, the kinetic parameters were defined including the effective delayed neutron fraction, the prompt neutron lifetime, and the neutron generation time. A new calculation methodology has been developed at ANL to simulate the pulsed neutron source experiments. In this methodology, the MCNP code is used to simulate the detector response from a single pulse of the external neutron source and a C code is used to superimpose the pulse until the

New Pulsed Orbit Bump Magnets for the Fermilab Booster Synchrotron

CERN Document Server

Lackey, James; John, Carson; Kashikhin, Vladimir; Makarov, Alexander; Prebys, Eric

2005-01-01

The beam from the Fermilab Linac is injected onto a bump in the closed orbit of the Booster Synchrotron where a carbon foil strips the electrons from the Linac’s negative ion hydrogen beam. Although the Booster itself runs at 15Hz, heat dissipation in the orbit bump magnets has been one limitation to the fraction of the cycles that can be used for beam. New, 0.28T pulsed window frame dipole magnets have been constructed that will fit into the same space as the old ones, run at the full repetition rate of the Booster, and provide a larger bump to allow a cleaner injection orbit. The new magnets use a high saturation flux density Ni-Zn ferrite in the yoke rather than laminated steel. The presented magnetic design includes two and three dimensional magnetic field calculations with eddy currents and ferrite nonlinear effects.

Nutritional knowledge following interventional educational sessions in children on regular hemodialysis

Directory of Open Access Journals (Sweden)

Doaa Mohammed Youssef

2015-01-01

Full Text Available To evaluate the impact of nutritional knowledge following interventional educational sessions in chronic dialysis patients, we studied 40 children on chronic regular hemodialysis (HD at the beginning and after six months of nutrition educational sessions using a predesigned questionnaire. We also measured the anthropometric parameters of nutrition to evaluate the impact of this education on the health of patients. We found a highly statistically significant increase in patients′ scores and in adequate knowledge using the questionnaire after the educational sessions. Our results showed a statistically significant decrease in body mass index and weight after educational sessions for six months. Moreover, there were no significant decreases in serum phosphorus, ferritin, iron and creatinine, in contrast with no significant increase in hemoglobin, serum calcium, blood urea nitrogen and serum albumin. We conclude that nutritional education is significantly effective with regard to the level of knowledge, but not with regard to the attitude and practice in children on chronic HD.

Nutritional knowledge following interventional educational sessions in children on regular hemodialysis.

Science.gov (United States)

Youssef, Doaa Mohammed; Abo Al Fotoh, Mohammad Nagib; Elibehidy, Rabab Mohamed; Ramadan, Shreen Magdy Ahmad; Mohammad, Ehab Mohammady

2015-03-01

To evaluate the impact of nutritional knowledge following interventional educational sessions in chronic dialysis patients, we studied 40 children on chronic regular hemodialysis (HD) at the beginning and after six months of nutrition educational sessions using a predesigned questionnaire. We also measured the anthropometric parameters of nutrition to evaluate the impact of this education on the health of patients. We found a highly statistically significant increase in patients' scores and in adequate knowledge using the questionnaire after the educational sessions. Our results showed a statistically significant decrease in body mass index and weight after educational sessions for six months. Moreover, there were no significant decreases in serum phosphorus, ferritin, iron and creatinine, in contrast with no significant increase in hemoglobin, serum calcium, blood urea nitrogen and serum albumin. We conclude that nutritional education is significantly effective with regard to the level of knowledge, but not with regard to the attitude and practice in children on chronic HD.

ErythropoieSIS stimulating agent (ESA use is increased following missed dialysis sessions

Directory of Open Access Journals (Sweden)

T. Christopher Bond

2012-06-01

Missed session episodes result in significant increases in ESA utilization in the post-miss period, and also in total monthly ESA use. Such increases should be considered in any assessment of impact of missed sessions: both clinical and economic.

47 CFR 73.827 - Interference to the input signals of FM translator or FM booster stations.

Science.gov (United States)

2010-10-01

... translator or FM booster stations. 73.827 Section 73.827 Telecommunication FEDERAL COMMUNICATIONS COMMISSION... Interference to the input signals of FM translator or FM booster stations. (a) An authorized LPFM station will not be permitted to continue to operate if an FM translator or FM booster station demonstrates that...

Data acquisition and control of the Zero Gradient Synchrotron 500 MeV booster synchrotron

International Nuclear Information System (INIS)

Timm, R.E.; Forrestal, J.; Hogrefe, R.; Voss, D.

1977-01-01

A data acquisition and control philosophy for the Zero Gradient Synchrotron (ZGS) 500 MeV booster has involved a top down design incorporating all of the systems comprising the booster. Consideration of operational complexity was necessary because the booster is to be used simultaneously for ZGS injection, and solid state physics studies. Existing software and hardware capabilities of the ZGS computer were considered. The resulting data acquisition and control system is based on a mix of sequential logic and a minicomputer. Hardware considerations were based on a ten year life expectancy of the booster. Due to time, budget, and manpower constraints, the incorporation of the total design has been divided into three phases of implementation. The first phase is covered and the remaining phases are outlined

Space shuttle booster multi-engine base flow analysis

Science.gov (United States)

Tang, H. H.; Gardiner, C. R.; Anderson, W. A.; Navickas, J.

1972-01-01

A comprehensive review of currently available techniques pertinent to several prominent aspects of the base thermal problem of the space shuttle booster is given along with a brief review of experimental results. A tractable engineering analysis, capable of predicting the power-on base pressure, base heating, and other base thermal environmental conditions, such as base gas temperature, is presented and used for an analysis of various space shuttle booster configurations. The analysis consists of a rational combination of theoretical treatments of the prominent flow interaction phenomena in the base region. These theories consider jet mixing, plume flow, axisymmetric flow effects, base injection, recirculating flow dynamics, and various modes of heat transfer. Such effects as initial boundary layer expansion at the nozzle lip, reattachment, recompression, choked vent flow, and nonisoenergetic mixing processes are included in the analysis. A unified method was developed and programmed to numerically obtain compatible solutions for the various flow field components in both flight and ground test conditions. Preliminary prediction for a 12-engine space shuttle booster base thermal environment was obtained for a typical trajectory history. Theoretical predictions were also obtained for some clustered-engine experimental conditions. Results indicate good agreement between the data and theoretical predicitons.

Effect of reactor finiteness on the boundary condition at the surface of a booster section

International Nuclear Information System (INIS)

Wassef, W.A.

1982-01-01

Effect of reactor finiteness on the boundary condition at the surface of an absorbing booster embedded in the reactor core is studied and formulated. The model used in these calculations depends on the Pl-Transport coupling technique. This method takes into consideration the rigorous neutron transport behavior inside the booster medium, while the Pl-approximation in the bulk of the scattering medium surrounding the booster which can be considered infinite in most practical applications. The neutron flux gradient parallel to the surface of the booster is considered. The geometrical configuration of the reactor core cross section is circular or rectangular. Finiteness of the reactor is introduced in the general formulation through its dimensions or buckling. Extensive numerical results are given to demonstrate the dependence of the boundary condition at the surface of the booster section on the reactor finiteness and the different physical parameters

AGS BOOSTER BEAM POSITION, TUNE, AND LONGITUDINAL PROFILE DATA ACQUISITION SYSTEM

International Nuclear Information System (INIS)

BROWN, K.A.; AHRENS, L.; SEVERINO, F; SMITH, K.; WILINSKI, M

2003-01-01

In this paper we will describe a data acquisition system designed and developed for the AGS Booster. The system was motivated by the need to get high quality beam diagnostics from the AGS Booster. This was accomplished by locating the electronics and digital data acquisition close to the Booster ring, to minimize loss of bandwidth in the original signals. In addition we had to develop the system rapidly and at a low cost. The system consists of a Lecroy digital oscilloscope which is interfaced through a National Instruments LabView(trademark) server application, developed for this project. This allows multiple client applications to time share the scope without interfering with each other. We will present a description of the system design along with example clients that we have implemented

Reusable Boosters in a European-Russian Perspective

Science.gov (United States)

Deneu, François; Ramiandrasoa, Fabienne

2002-01-01

In 2001, EADS and Khrunichev SRPSC have initiated and carried out a working group devoted to the analysis of potential common studies and developments in the field of space activities. This working group came up with several propositions of interest, among which, the use of reusable boosters issued from Khrunichev previous design appeared to be promising when applied to heavy type launchers. Although the results required to be confirmed by detailed studies prior to final conclusions, preliminary studies have shown the interest of Ariane 5 configurations using such reusable booster in view of reducing the specific and launch cost as well as potentially increasing the performance. In November 2001, EADS and KHRUNICHEV SRPSC have started a study on an Ariane 5 plus reusable boosters configuration. This study aims at obtaining a better understanding of the advantages and drawbacks attached to such a use. Technical feasibility is more in depth analysed, with all recurring and not recurring aspects (including launch infrastructure modifications). Programmatic aspects are also addressed in order to better assess potential economic advantages and unavoidable drawbacks. Beyond that the identification of what could be, for western Europe and Russian players, an efficient and pay- off industrial organisation, is also a study theme of importance. This papers intends to present the main results achieved within this study and the propositions for the future which are likely to provide western Europe and Russia with stronger positions in the competitive field of launch business.

Automated tuning of the advanced photon source booster synchrotron

International Nuclear Information System (INIS)

Biedron, S.G.; Milton, S.V.

1997-01-01

The acceleration cycle of the Advanced Photon Source (APS) booster synchrotron is completed within 223 ms and is repeated at 2 Hz. Unless properly corrected, transverse and longitudinal injection errors can lead to inefficient booster performance. In order to simplify daily operation, automated tuning methods have been developed. Through the use of beam position monitor (BPM) reading, transfer line corrector magnets, magnet ramp timing, and empirically determined response functions, the injection process is optimized by correcting the first turn trajectory to the measured closed orbit. These tuning algorithms and their implementation are described here along with an evaluation of their performance

Multi-Physics Analysis of the Fermilab Booster RF Cavity

International Nuclear Information System (INIS)

Awida, M.; Reid, J.; Yakovlev, V.; Lebedev, V.; Khabiboulline, T.; Champion, M.

2012-01-01

After about 40 years of operation the RF accelerating cavities in Fermilab Booster need an upgrade to improve their reliability and to increase the repetition rate in order to support a future experimental program. An increase in the repetition rate from 7 to 15 Hz entails increasing the power dissipation in the RF cavities, their ferrite loaded tuners, and HOM dampers. The increased duty factor requires careful modelling for the RF heating effects in the cavity. A multi-physic analysis investigating both the RF and thermal properties of Booster cavity under various operating conditions is presented in this paper.

Booster Long 13 irradiation studies

Energy Technology Data Exchange (ETDEWEB)

Leveling, A.; Mokhov, N.; Moore, C.D.; /Fermilab

1998-06-01

Extraction from the Booster to the Main Ring occurred at Long Straight 13. The nature of the extraction process was such that 1% to 2% of the beam was lost in this region. There was an appreciable amount of beam extracted as shown in Table 1, which gives the yearly integrated intensities from 1973 to 1997. A simple model of the extraction losses was set up by Chandra Bhat utilizing the program CASIM. A sample output I shown in figure 1 which gives contours of stars/cm3 in the dirt, also schematically depicted are the three six feet deep sampling holes which were drilled to map out this cascade. One aspect of this study has been the study of the production of non-migrating nuclides and further study may in fact yield better values for the K parameter, the probability per star that an atom of the particular nuclide will be produced. Also the results of this study can give experimental numbers for the production of other nuclides when the amount of Na22 has been calculated. However, the most important part of this study has been the determination of the amount of tritium produced by extraction from the Booster and the experimentally determined migration rate. If we look at the top sample result in hole S2 of 777 pCi/ml of tritium and use the experimentally determined rate of migration and the depth to the aquifer of 13.1m, they calculate that the concentration will have decayed away to 1.1E-8 pCi/ml. If we look at the bottom sample, which is 11.3 m away from the aquifer, they calculate that the 116 pCi/ml will have decayed to 5.2E-8 pCi/ml. The conclusions is that the rate of migration determined over the 24 year irradiation history of the Booster extraction point is small enough that there is no problem with migration of tritium to the aquifer.

Tune measurement in the NSLS booster synchrotron

International Nuclear Information System (INIS)

Blum, E.B.; Nawrocky, R.

1993-01-01

The NSLS booster synchrotron can accelerate an electron beam from approximately 80 to 750 MeV in 0.7 sec. The betatron tunes can change during acceleration by as much as 0.1 units, causing beam loss as they cross resonance lines. Precise measurements with a conventional swept spectrum analyzer have always been difficult because of the rapid variation of tune as the magnets are ramped. We are now using a system based on a Tektronix 3052 digital spectrum analyzer that can obtain a complete frequency spectrum over a 10 MHz bandwidth in 200 μsec. Betatron oscillations are stimulated for the measurements by applying white noise to the beam through stripline electrodes. We will describe the instrumentation, our measurements of tune as a function time during the acceleration cycle, and the resulting improvements to the booster operation

Beam current monitoring in the AGS Booster and its transfer lines

International Nuclear Information System (INIS)

Witkover, R.L.; Zitvogel, E.; Castillo, V.

1991-01-01

The new AGS Booster is designed to accelerate low intensity polarized protons and heavy ions, and high intensity protons. The wide range of beam parameters and the vacuum, thermal and radiation environment, presented challenges in the instrumentation design. This paper describes the problems and solutions for the beam current monitors in the Booster and its transport lines. Where available, results of the initial operation will be presented. 11 refs., 3 figs

Study of solid rocket motors for a space shuttle booster. Volume 1: Executive summary

Science.gov (United States)

1972-01-01

The design, development, production, and launch support analysis for determining the solid propellant rocket engine to be used with the space shuttle are discussed. Specific program objectives considered were: (1) definition of engine designs to satisfy the performance and configuration requirements of the various vehicle/booster concepts, (2) definition of requirements to produce booster stages at rates of 60, 40, 20, and 10 launches per year in a man-rated system, and (3) estimation of costs for the defined SRM booster stages.

Immunogenicity and Safety of a Booster Injection of DTap-IPV//Hib (Pentaxim) Administered Concomitantly With Tetravalent Dengue Vaccine in Healthy Toddlers 15-18 Months of Age in Mexico: A Randomized Trial.

Science.gov (United States)

Melo, Flor Irene Rodriguez; Morales, José Juan Renteria; De Los Santos, Abiel Homero Mascareñas; Rivas, Enrique; Vigne, Claire; Noriega, Fernando

2017-06-01

The live, attenuated, tetravalent dengue vaccine (CYD-TDV) is licensed in a number of dengue endemic countries for individuals ≥9 years of age. Before the integration of any vaccine into childhood vaccination schedules, a lack of immune interference and acceptable safety when coadministered with other recommended vaccines should be demonstrated. This randomized, multi-center phase III trial was conducted in Mexico. Healthy toddlers (n = 732) received a booster dose of a licensed pentavalent combination vaccine [diphtheria, tetanus, acellular pertussis, inactivated polio vaccine and Haemophilus influenzae type b (DTaP-IPV//Hib)] either concomitantly or sequentially, with the second dose of CYD-TDV administered as a 3-dose schedule. Antibody titers against diphtheria toxoid, tetanus toxoid and pertussis antigens were measured by enzyme-linked immunosorbent assay. Antibodies against poliovirus and dengue serotypes were measured using a plaque reduction neutralization test. Noninferiority was demonstrated for each of the DTaP-IPV//Hib antigens if the lower limit of the 2-sided 95% confidence interval of the difference in seroconversion rates between the 2 groups (CYD-TDV and placebo) was ≥10%. Safety of both vaccines was assessed. Noninferiority in immune response was demonstrated for all DTaP-IPV//Hib antigens. After 3 doses of CYD-TDV, no difference was observed in the immune response for CYD-TDV between groups. There were no safety concerns during the study. Coadministration of the DTaP-IPV//Hib booster vaccine with CYD-TDV has no observed impact on the immunogenicity or safety profile of the DTaP-IPV//Hib booster vaccine. No difference was observed on the CYD-TDV profile when administered concomitantly or sequentially with the DTaP-IPV//Hib booster vaccine.

OPTIMASI DAYA MESIN DAN KONSUMSI BAHAN BAKAR MESIN TOYOTA SERI 5K MELALUI PENGGUNAAN PENGAPIAN BOOSTER

Directory of Open Access Journals (Sweden)

Mardani Ali Sera

2015-10-01

Full Text Available Proses pembakaran adalah proses secara fisik yang terjadi di dalam silinder. Proses pembakaran dimulai pada saat busi memercikkan bunga api hingga terjadi proses pembakaran. Dalam penelitian ini digunakan metode eksperimen yaitu membandingkan daya dan konsumsi bahan bakar antara pengapian standar dengan pengapian menggunakan booster. Berdasarkan data hasil uji coba perbandingan antara sistem pengapian standar dengan pengapian yang menggunakan booster dengan objek penelitian mesin Toyota seri 5K diketahui adanya kenaikan 2.61% daya menjadi 27.723 kW dari 27.17 kW antara sistem pengapian standar dengan pengapian yang menggunakan booster pada putaran mesin 2400 rpm. Sedangkan prosentase kenaikan rerata daya sebesar 2.79 %. Penggunaan booster juga membuat penggunaan konsumsi bahan bakar spesifik (sfc antara sistem pengapian standar dengan pengapian yang menggunakan booster. Prosentase penurunan rerata konsumsi bahan bakar spesifik (sfc sebesar 6.99%. Pada sistem pengapian yang menggunakan booster, sfc minimum sebesar 0.219 kg/kWh pada putaran mesin 2200 rpm. Pada pengapian standar sfc minimum sebesar 0.231 kg/kWh pada putaran mesin 2400 rpm.

Efficacy and safety of RTS,S/AS01 malaria vaccine with or without a booster dose in infants and children in Africa

DEFF Research Database (Denmark)

Theander, Thor Grundtvig; Lusingu, John Peter Andrea

2015-01-01

and a booster dose at month 20 (R3R group); three doses of RTS,S/AS01 and a dose of comparator vaccine at month 20 (R3C group); or a comparator vaccine at months 0, 1, 2, and 20 (C3C [control group]). Participants were followed up until Jan 31, 2014. Cases of clinical and severe malaria were captured through......, the vaccine has the potential to make a substantial contribution to malaria control when used in combination with other effective control measures, especially in areas of high transmission. FUNDING: GlaxoSmithKline Biologicals SA and the PATH Malaria Vaccine Initiative....

Integral Ramjet Booster Demonstration Program

Science.gov (United States)

1975-02-01

vibration loads before motor firing at -65, +70, and +1650F, (2) The chambers are fabricated from roll and welded ( TIG ) L-605 sheet that is cold...Typical Integral Booster Internal Configuration Keyhole Grain Pressure and Thrust Versus Time (+700F, Sea Level) Keyhole Grain Pressure and...Thrust Versus Time (+1650F, Sea Level) Keyhole Grain Pressure and Thrust Versus Time (-65^, Sea Level) Radial-Slot Grain Design Radial-Slot Grain

Injection system of teh SSC Medium Energy Booster

International Nuclear Information System (INIS)

Mao, N.; Gerig, R.; McGill, J.; Brown, K.

1994-04-01

The Medium Energy Booster (MEB) is the third of the SSCL accelerators and the largest of the resistive magnet synchrotrons. It accelerates protons from an injection momentum of 12 GeV/c to a top momentum of 200 GeV/c. A beam injection system has been designed to inject the beam transferred from the Low Energy Booster onto the MEB closed orbit in the MEB injection insertion region. The beam is injected via a vertical bending Lambertson septum magnet and a horizontal kicker with appropriate matching and very little beam loss and emittance dilution. The beam optics of the injection system is described in this paper. The required parameters of the Lambertson septum magnet and the injection kicker are given

Analysis of resonance-driving imperfections in the AGS Booster

International Nuclear Information System (INIS)

Gardner, C.; Shoji, Y.; Danby, G.; Glenn, J.W.; Jackson, G.J.; Soukas, A.; van Asselt, W.; Whalen, C.

1994-01-01

At the design intensity of 1.5 x 10 13 ppp, the space charge tune shift in the AGS Booster at injection has been estimated to be about 0.35. The beam tunes are therefore spread over many lower order resonance lines and the associated stopbands must be corrected in order to minimize the amplitude growth due to resonance excitation. This requires proper compensation of the resonance-driving harmonics which result from random magnetic field errors. The observation and correction of second and third order resonance stopbands in the AGS Booster is reviewed, and an analysis of magnetic field imperfections based on the required corrections is given

Design of the AGS Booster Beam Position Monitor electronics

International Nuclear Information System (INIS)

Ciardullo, D.J.; Smith, G.A.; Beadle, E.R.

1991-01-01

The operational requirements of the AGS Booster Beam Position Monitor system necessitate the use of electronics with wide dynamic range and broad instantaneous bandwidth. Bunch synchronization is provided by a remote timing sequencer coupled to the local ring electronics via digital fiber-optic links. The Sequencer and local ring circuitry work together to provide single turn trajectory or average orbit and intensity information, integrated over 1 to 225 bunches. Test capabilities are built in for the purpose of enhancing BPM system accuracy. This paper describes the design of the Booster Beam Position Monitor electronics, and presents performance details of the front end processing, acquisition and timing circuitry

Measured longitudinal beam impedance of booster gradient magnets; TOPICAL

International Nuclear Information System (INIS)

James L Crisp and Brian J. Fellenz

2001-01-01

The Booster gradient magnets have no vacuum pipe which forces the beam image current to flow along the laminated pole tips. Both D and F style magnets were measured with a stretched wire to determine the longitudinal beam impedance caused by these laminations. Results are compared to calculations done 30 years ago. The inductive part of the magnet impedance is interesting because it partially compensates for the negative inductance effects of space charge on the beam. An R/L circuit consisting of 37K(center d ot) in parallel with between 40 and 100uH is a reasonable approximation to the total impedance of Booster magnet laminations

Closing session

International Nuclear Information System (INIS)

2014-01-01

This part makes a summary of the different sessions and discussions of the workshop in a series of slide presentations: Summary of Opening Session; Summary of Session 1: Analysis of External Hazard Potential; Summary of session 2: Specific features of analysis and modeling of particular natural external hazards; Summary of session-3: Practices and research efforts on natural external events PSA; Summary of session 4: Modeling of NPP response to natural external events in PSA; Summary of session 5: Seismic Risk Analysis; Summary of session 6: Use of external events PSA with the focus on regulatory body role; Facilitated discussion 1 summary: Where do we stand in the analysis of external events?; Summary Facilitated Discussion 2: Findings and Good Practices for External Events Analysis

Observation and correction of resonance stopbands in the AGS Booster

International Nuclear Information System (INIS)

Gardner, C.; Shoji, Y.; Ahrens, L.; Glenn, J.W.; Lee, Y.Y.; Roser, T.; Soukas, A.; van Asselt, W.; Weng, W.T.

1993-01-01

At the design intensity of 1.5 x 10 13 ppp, the space charge tune shift in the AGS Booster at injection has been estimated to be about 0.35. Therefore, the beam is spread over may lower order resonance lines and the stopbands have to be corrected to minimize the amplitude growth by proper compensation of the driving harmonics resulting from random errors. The observation and correction of second and third order resonance stopbands in the AGS Booster, and the establishment of a favorable operating point at high intensity are discussed

Vertical septum magnets for distributing the beam to the 4 PS Booster rings

CERN Multimedia

Ordan, Julien Marius

2017-01-01

To facilitate H- injection from Linac4 to the PS Booster via the transfer line the BI.SMV10 (Booster Injection Septum Magnet Vertical) provides the vertical deflection of the 160 MeV H- beam to rings 1, 2 and 4 of the Booster. Currently this system is capable of deflecting 50 MeV protons and comprises an assembly of ferrite type magnets in an “omega” section vacuum tank (see fig. 1). The current system shall be replaced with a UHV compatible vacuum chamber incorporating 3 sets of double septum magnets, pulsed from 3 individual power supplies via transformers with 12:1 ratio.

Anti-HBs in immunized children with cuban hepatitis B vaccine and impact of booster dose after five years

International Nuclear Information System (INIS)

Dahifar, H.; Mousavi, F.; Ghorbani, A.

2008-01-01

Hepatitis B virus infection and associated diseases are a major public health problem. This study was planned to find out the persistence of antibody against hepatitis B surface antigen in Iranian vaccinated children after five years. Anti-HBs titers in a group of healthy good - responder children who were vaccinated with Cuban hepatitis B vaccine in infancy were measured after five years. Children with antibody titers <100 mlU/ml were revaccinated and retested after four weeks. Mean anti-HBs titers in 68 children (29 females, 39 males) were 482.1 mlU/ml at six months after the third dose of primary vaccination and 153 mlU/ml at five years later. Total mean anti-HBs titers in 36 (52.9%) children out of 68 (17 females, 19 males) were 38.3 mlU/ml and 4(5.8%) of 68 children (two of each sexes) had no detectable antibody after five years. Total mean anti-HBs titers in these hypo- responder and non- responder were 774.3 mlU/ml and 625.5 mlU/ml respectively after booster dose. In a group of children, who were immunized with Cuban hepatitis B vaccine from birth, anti-HBS titers fell at 6.5 years of age and almost half of children became hypo responder or no responder and their anti-HBs titers developed secondary rise after booster vaccination. All children showed immunologic memory to a booster dose. (author)

Percutaneous ASD and VSD closure of 4-month-old infant in the same session

Directory of Open Access Journals (Sweden)

Nazmi Narin

2015-09-01

In conclusion, percutaneous ASD, VSD closure is being done safely in children, but for the first time, percutaneous VSD closure was done in an infant with low body weight in the same session with ASD closure successfully. This case will be an encouraging example for the future.

Compensation of dogleg effect in Fermilab Booster

CERN Document Server

Xiao Biao Huang

2003-01-01

The edge focusing of dogleg magnets in Fermilab Booster has been causing severe distortion to the horizontal linear optics. The doglegs are vertical rectangular bends, therefore the vertical edge focusing is canceled by body focusing and the overall effect is focusing in the horizontal plane. The maximum horizontal beta function is changed from 7m to 46.9m and maximum dispersion from 3.19m to 6.14m. Beam size increases accordingly. This is believed to be one of the major reasons of beam loss. In this technote we demonstrate that this effect can be effectively corrected with Booster's quadrupole correctors in short straight sections (QS). There are 24 QS correctors which can alter horizontal linear optics with negligible perturbation to the vertical plane. The currents of correctors are determined by harmonic compensation, i.e., cancellation of dogleg's harmonics that are responsible for the distortion with that of QS correctors. By considering a few leading harmonics, the ideal lattice can be partly restored....

Design and status of the AGS booster accelerator

International Nuclear Information System (INIS)

Forsyth, E.B.; Lee, Y.Y.

1987-01-01

Comments are given on some areas of the design considered for the AGS Booster Accelerator, including lattice design, energy and repetition rate, injection, radio frequency system, and the vacuum system. The current status is then briefly described

Design and status of the AGS booster accelerator

Energy Technology Data Exchange (ETDEWEB)

Forsyth, E.B.; Lee, Y.Y.

1987-01-01

Comments are given on some areas of the design considered for the AGS Booster Accelerator, including lattice design, energy and repetition rate, injection, radio frequency system, and the vacuum system. The current status is then briefly described. (LEW)

Controlling memory impairment in elderly adults using virtual reality memory training: a randomized controlled pilot study.

Science.gov (United States)

Optale, Gabriele; Urgesi, Cosimo; Busato, Valentina; Marin, Silvia; Piron, Lamberto; Priftis, Konstantinos; Gamberini, Luciano; Capodieci, Salvatore; Bordin, Adalberto

2010-05-01

Memory decline is a prevalent aspect of aging but may also be the first sign of cognitive pathology. Virtual reality (VR) using immersion and interaction may provide new approaches to the treatment of memory deficits in elderly individuals. The authors implemented a VR training intervention to try to lessen cognitive decline and improve memory functions. The authors randomly assigned 36 elderly residents of a rest care facility (median age 80 years) who were impaired on the Verbal Story Recall Test either to the experimental group (EG) or the control group (CG). The EG underwent 6 months of VR memory training (VRMT) that involved auditory stimulation and VR experiences in path finding. The initial training phase lasted 3 months (3 auditory and 3 VR sessions every 2 weeks), and there was a booster training phase during the following 3 months (1 auditory and 1 VR session per week). The CG underwent equivalent face-to-face training sessions using music therapy. Both groups participated in social and creative and assisted-mobility activities. Neuropsychological and functional evaluations were performed at baseline, after the initial training phase, and after the booster training phase. The EG showed significant improvements in memory tests, especially in long-term recall with an effect size of 0.7 and in several other aspects of cognition. In contrast, the CG showed progressive decline. The authors suggest that VRMT may improve memory function in elderly adults by enhancing focused attention.

Energy-efficient operation of a booster RF system for Taiwan light source operated in top-up mode

International Nuclear Information System (INIS)

Yeh, Meng-Shu; Wang, Chaoen; Chang, Lung-Hai; Chung, Fu-Tsai; Yu, Tsung-Chi; Lin, Ming-Chyuan; Chen, Ling-Jhen; Yang, Tz-Te; Chang, Mei-Hsia; Lin, Yu-Han; Tsai, Ming-Hsun; Lo, Chih-Hung; Liu, Zong-Kai

2015-01-01

Contemporary light sources operate in a top-up mode to maintain their photon intensity quasi-constant so as to improve significantly the thermal stability of the photon beam and to maximize ultimately the average photon flux at a designed maximum operational beam current. Operating in a top-up mode requires frequent beam injection from the synchrotron booster to the storage ring of the light source, but the injection intervals occupy only a tiny portion of the operational time of the integrated machine. To maintain a high operational reliability, the booster RF system practically operates necessarily under injection conditions around the clock and consumes full electric power whether during top-up injection or not. How to decrease the power consumption of the booster RF system during its stand-by time but not to sacrifice the reliability and availability of the RF system is obviously of fundamental interest for routine operation of the light source in a top-up mode. Here, an energy-efficient operation of a booster RF system adaptive to top-up operation of a light source is proposed that has been developed, realized and integrated into the booster RF system of the Taiwan Light Source (TLS), and routinely operated since the end of year 2008. The klystron cathode current and RF gap voltage of the booster's accelerating RF cavity are both periodically modulated to adapt the injection rhythm during top-up operation, which results in decreased consumption of electric power of the booster RF system by more than 78%. The impact on the reliability and availability of the booster RF system has been carefully monitored during the past five operational years, delivering more than 5000 h scheduled user beam time per year. The booster RF system retains its excellent reliability and availability as previously. Neither a decrease of the service time nor an induced reliability issue from the klystron or any high-power high-voltage component of the transmitter has been

Immunogenicity, safety, and antibody persistence at 3, 5, and 10 years postvaccination in adolescents randomized to booster immunization with a combined tetanus, diphtheria, 5-component acellular pertussis, and inactivated poliomyelitis vaccine administered with a hepatitis B virus vaccine concurrently or 1 month apart.

Science.gov (United States)

Embree, Joanne; Law, Barbara; Voloshen, Tim; Tomovici, Antigona

2015-03-01

An understanding of the antibody persistence elicited by a combined tetanus, diphtheria, 5-component acellular pertussis, and inactivated poliovirus vaccine (Tdap-IPV) after adolescent vaccination is important to optimize booster dosing intervals. Our objectives were to compare the safety and immunogenicity of Tdap-IPV coadministered with hepatitis B vaccine (HepB) and sequential administration and evaluate humoral immunity at 3, 5, and 10 years after Tdap-IPV vaccination in adolescents. This phase II randomized, controlled, and open-label study enrolled 280 11- to 14-year-old adolescents with up to 10 years postvaccination follow-up. Group 1 (n = 145) received Tdap-IPV, followed by a HepB dose 1 month later, and group 2 (n = 135) received both vaccines simultaneously. No consistent increases in solicited reactions or unsolicited adverse events occurred with coadministration. All vaccinees attained seroprotective antibody levels at ≥0.01 IU/ml for diphtheria and tetanus, at a ≥1:8 dilution for poliovirus (serotypes 1, 2, and 3), and ≥10 mIU/ml for hepatitis B at 1 month postvaccination. Clinically relevant immunologic interactions did not occur with coadministration. For pertussis, all participants achieved seropositivity levels (at or above the lower limit of quantitation), and 72.7% to 95.8% had 4-fold increases in pertussis antibodies at 1 month postvaccination. At 10 years postvaccination, the remaining participants (62.8% of the original cohort) maintained seroprotective levels of ≥0.01 IU/ml for diphtheria and tetanus, a ≥1:8 dilution for all 3 poliovirus serotypes, and 74.1% to 98.2% maintained pertussis seropositivity levels depending on the antigen tested. There were no differences between the groups. These results support the coadministration of Tdap-IPV and HepB to adolescents and suggest that vaccination with Tdap-IPV can offer protection for 10 years after an adolescent booster vaccination. Copyright © 2015, American Society for Microbiology

Preliminary study of AC power feeders for AGS booster

International Nuclear Information System (INIS)

Meth, M.

1992-01-01

It has been proposed that the AGS Heavy Ion/Proton Booster be excited directly from the electric power distribution system without intervening an energy storage buffer such as an MG set or a magnetic energy buffer. The average power requirement of the AGS Booster is less than many single-loads presently housed on the lab site. However, the power swing will be the largest single pulsating load on the lab site. The large power swings will impact on the power grid producing utility-line disturbances such as voltage fluctuations and harmonic generation. Thus, it is necessary to carefully evaluate the quality of the electric power system resulting from the interconnection, such that the utility system is not degraded either on the lab site or at LILCO's substation

The 1.4 GeV PS Booster in its tunnel.

CERN Multimedia

Patrice Loïez

2002-01-01

The PS Improvement Programme, launched as early as 1964, had a "Booster" as the key element in the quest for higher beam intensity and density. These were limited in the PS at injection of the 50 MeV proton beam from the linac by the incoherent (Laslett-) Q-shift. Boosting the linac beam to 800 MeV would raise the PS intensity limit by an order of magnitude, from 1E12 protons per pulse to 1E13. The main motivation was the supply of intense beams to the ISR. Soon, the Booster proved to be crucial for the neutral current experiment. A unique feature of the Booster are its 4 superposed rings. Its lattice is also unusual: between its 32 bending magnets, every second straight section contains a quadrupole triplet (F,D,F), while the alternate ones are drift spaces (mostly filled with essential components like septa, kickers, RF-cavities, etc.). In each picture we see one of the 16 periods. Following the direction of the beam from right to left: a bending magnet (green); an empty straight section; a bending magnet; ...

Magnet power supply system for the ALS storage ring and booster

International Nuclear Information System (INIS)

Jackson, L.T.; Luchini, K.; Lutz, I.

1993-05-01

The Magnet Power Supply System is described by specification, design, hardware, and operating experience. A unique system for the one Hz, 1.5 GeV Booster, where the wideband QF and QD power supplies track the dipole current to within 0.1% at injection will be detailed. AC distribution system considerations related to inverting the stored energy of the booster magnet back into power grid will be discussed. The rational for linear correctors and individual quad supplies (225 total units) will be placed within the context of the storage-ring requirements

Liquid Rocket Booster (LRB) for the Space Transportation System (STS) Systems Study; Volume 1 - Executive Summary

National Research Council Canada - National Science Library

Ware, Larry

1989-01-01

...) solid rocket boosters (SRBs) with liquid rocket boosters (LRBs), Figure 1.0-1. The main objectives of a LRB substitution for the SRB were increased STS safety and reliability and increased payload performance...

Misuse of booster cushions - an observation study of children's performance during buckling up.

Science.gov (United States)

Osvalder, Anna-Lisa; Bohman, Katarina

2008-10-01

Booster cushions are effective tools to protect children from injuries in car crashes, but there remains a large amount of misuse. The aim of this study was to assess potential misuse of booster cushions in an observational laboratory study, and to identify whether booster cushion design, age or clothing had any effect. 130 Swedish children from the ages of 4-12 years participated. Each child buckled up on an integrated and on an aftermarket booster cushion in the rear seat. The older children also buckled up with seat belt only. Interviews, observations and body measurements were performed. Time to buckle up and amount of belt slack were registered. Photographs were taken to document misuse. Results showed that 77% failed to perform correct belt routing on the aftermarket cushion, independent of age, although they were familiar with this system. The misuse rate for the integrated cushion was only 4%. No misuse was found for seat belt only. Few children tightened the belt. The belt slack increased when wearing winter jackets. This indicates the importance of adding pretensioners to the rear seat. Sled tests with HIII&TNO 6y dummies were also performed for the most frequent misuse situations found. The main conclusion is that an integrated booster cushion has many advantages compared to an aftermarket cushion regarding both safety and comfort. It is easy and quick to handle, has few possibilities for misuse, has an intuitive design, the buckling up sequence is equal to buckling up with an ordinary seat belt, and younger children can buckle up correctly.

Efficacy of a minimal home-based psychoeducative intervention versus usual care for managing anxiety and dyspnoea in patients with severe chronic obstructive pulmonary disease

DEFF Research Database (Denmark)

Bove, Dorthe Gaby; Overgaard, Dorthe; Lomborg, Kirsten

2015-01-01

investigates the efficacy of a minimal home-based psychoeducative intervention versus usual care for patients with severe chronic obstructive pulmonary disease. METHODS AND ANALYSIS: The trial is a randomised controlled trial with a 4-week and 3-month follow-up. 66 patients with severe chronic obstructive...... pulmonary disease and associated anxiety will be randomised 1:1 to either an intervention or control group. The intervention consists of a single psychoeducative session in the patient's home in combination with a telephone booster session. The intervention is based on a manual, with a theoretical...

Integrated hydraulic booster/tool string technology for unfreezing of stuck downhole strings in horizontal wells

Science.gov (United States)

Tian, Q. Z.

2017-12-01

It is common to use a jarring tool to unfreeze stuck downhole string. However, in a horizontal well, influenced by the friction caused by the deviated section, jarring effect is poor; on the other hand, the forcing point can be located in the horizontal section by a hydraulic booster and the friction can be reduced, but it is time-consuming and easy to break downhole string using a large-tonnage and constant pull force. A hydraulic booster - jar tool string has been developed for unfreezing operation in horizontal wells. The technical solution involves three elements: a two-stage parallel spring cylinder structure for increasing the energy storage capacity of spring accelerators; multiple groups of spring accelerators connected in series to increase the working stroke; a hydraulic booster intensifying jarring force. The integrated unfreezing tool string based on these three elements can effectively overcome the friction caused by a deviated borehole, and thus unfreeze a stuck string with the interaction of the hydraulic booster and the mechanical jar which form an alternatively dynamic load. Experimental results show that the jarring performance parameters of the hydraulic booster-jar unfreezing tool string for the horizontal wells are in accordance with original design requirements. Then field technical parameters were developed based on numerical simulation and experimental data. Field application shows that the hydraulic booster-jar unfreezing tool string is effective to free stuck downhole tools in a horizontal well, and it reduces hook load by 80% and lessens the requirement of workover equipment. This provides a new technology to unfreeze stuck downhole string in a horizontal well.

Present state of tandem superconductive booster of JAERI

Energy Technology Data Exchange (ETDEWEB)

Takeuchi, Suehiro; Matsuda, Makoto; Kanazawa, Shuhei; Yoshida, Tadashi; Ouchi, Isao; Shoji, Tokio [Japan Atomic Energy Research Inst., Tokai, Ibaraki (Japan). Tokai Research Establishment

1996-12-01

The superconductive booster constructed rear-stage accelerator of the tandem accelerator of the Tokai Research Establishment, JAERI (Japan Atomic Energy Research Institute), was completed in construction of its whole system on October, 1993, and through its beam accelerating test and remodulation its design characteristics were established on September, 1994. From November, 1994 to April, 1995 a repulsion-forming nuclear isolation apparatus was installed to modulate at target room, and was begun to use on June, 1995. The beam reaccelerated at the booster was used mainly for nuclear spectroscopy experiment, a collaborative research was developed using mini-crystal balls made by collecting from University of Tsukuba and so forth. The accelerating part of the booster is a phase independent setting type Linac consisting of 40 niobium superconducting holes with 1/4 wave-length type and 130 MHz in frequency, in which a hole can form 5 MV/m of accelerating electric field for 4 W of radio frequency spent power of 0.75 MV of accelerating voltage per hole, to form 30 MV of voltage in a whole. 4 holes are contained into each 10 cryostats, respectively. In accelerating tests, Si, Cl, Ni, Ge, Ag, I and Au ions are accelerated to establish 30 mV of total accelerating voltage in its design value, which reaches to their expected energy characteristics. Its used days in this year are 25 days after beginning of its use, and operating days of the cooling apparatus was 135 days in total. (G.K.)

Concentrated Ground Plane Booster Antenna Technology for Multiband Operation in Handset Devices

Directory of Open Access Journals (Sweden)

C. Picher

2014-12-01

Full Text Available The current demand in the handset antenna field requires multiband antennas due to the existence of multiple communication standards and the emergence of new ones. At the same time, antennas with reduced dimensions are strongly required in order to be easily integrated. In this sense, the paper proposes a compact radiating system that uses two non-resonant elements to properly excite the ground plane to solve the abovementioned shortcomings by minimizing the required Printed Circuit Board (PCB area while ensuring a multiband performance. These non-resonant elements are called here ground plane boosters since they excite an efficient mode of the ground plane. The proposed radiating system comprises two ground plane boosters of small dimensions of 5 mm x 5 mm x 5 mm. One is in charge of the low frequency region (0.824-0.960 GHz and the other is in charge of the high frequency region (1.710-2.170 GHz. With the aim of achieving a compact configuration, the two boosters are placed close to each other in a corner of the ground plane of a handset device (concentrated architecture. Several experiments related to the coupling between boosters have been carried out in two different platforms (barphone and smartphone, and the best position and the required matching network are presented. The novel proposal achieves multiband performance at GSM850/900/1800/1900 and UMTS.

A Randomized Controlled Trial to Evaluate a Potential Hepatitis B Booster Vaccination Strategy Using Combined Hepatitis A and B Vaccine.

Science.gov (United States)

Li, Fangjun; Hu, Yuansheng; Zhou, Youming; Chen, Lixin; Xia, Wei; Song, Yufei; Tan, Zhengliang; Gao, Lidong; Yang, Zhong; Zeng, Gang; Han, Xing; Li, Junhua; Li, Jing

2017-05-01

Booster doses could play a major role in no responders or low responders to primary hepatitis B (HB) vaccine. Planed time point for hepatitis A vaccination in China provides a good opportunity to carry out HB booster dose by using combined hepatitis A and B vaccine. A randomized, double-blinded clinical trial was conducted to compare the immunogenicity and safety of toddlers 18-24 months of age receiving 3 different vaccination regimens: 2 doses of inactivated hepatitis A vaccine (group 1), 1 dose of inactivated hepatitis A vaccine plus 1 dose of combined hepatitis A and B vaccine (group 2) or 2 doses of combined hepatitis A and B vaccine (group 3). All 3 groups showed 100% seroprotection for antihepatitis A virus antibody after vaccination. Seroprotection rate for anti-HB antibody before vaccination ranged from 79.5% to 92.9% in the 3 groups. After second inoculation, anti-HBs seroprotection increased from 92.9% to 100% in group 2 with postvaccination geometric mean concentration (GMC) of 2258.3 mIU/mL and from 79.5% to 98.9% in group 3 with postvaccination GMC of 2055.3 mIU/mL. The adverse events were not statistically different among groups (P = 0.345). Combined hepatitis A and B vaccine could stimulate high level of both antihepatitis A virus and anti-HBs antibodies and not increase adverse events, providing a new choice for HB booster.

History of the ZGS 500 MeV booster.

Energy Technology Data Exchange (ETDEWEB)

Simpson, J.; Martin; R.; Kustom, R.

2006-05-09

The history of the design and construction of the Argonne 500 MeV booster proton synchrotron from 1969 to 1982 is described. This accelerator has since been in steady use for the past 25 years to power the Argonne Intense Pulsed Neutron Source (IPNS).

Teaching Medical Students About "The Conversation": An Interactive Value-Based Advance Care Planning Session.

Science.gov (United States)

Lum, Hillary D; Dukes, Joanna; Church, Skotti; Abbott, Jean; Youngwerth, Jean M

2018-02-01

Advance care planning (ACP) promotes care consistent with patient wishes. Medical education should teach how to initiate value-based ACP conversations. To develop and evaluate an ACP educational session to teach medical students a value-based ACP process and to encourage students to take personal ACP action steps. Groups of third-year medical students participated in a 75-minute session using personal reflection and discussion framed by The Conversation Starter Kit. The Conversation Project is a free resource designed to help individuals and families express their wishes for end-of-life care. One hundred twenty-seven US third-year medical students participated in the session. Student evaluations immediately after the session and 1 month later via electronic survey. More than 90% of students positively evaluated the educational value of the session, including rating highly the opportunities to reflect on their own ACP and to use The Conversation Starter Kit. Many students (65%) reported prior ACP conversations. After the session, 73% reported plans to discuss ACP, 91% had thought about preferences for future medical care, and 39% had chosen a medical decision maker. Only a minority had completed an advance directive (14%) or talked with their health-care provider (1%). One month later, there was no evidence that the session increased students' actions regarding these same ACP action steps. A value-based ACP educational session using The Conversation Starter Kit successfully engaged medical students in learning about ACP conversations, both professionally and personally. This session may help students initiate conversations for themselves and their patients.

Improving the performance of booster heat pumps using zeotropic mixtures

DEFF Research Database (Denmark)

Zühlsdorf, B.; Meesenburg, W.; Ommen, T. S.

2018-01-01

Abstract This study demonstrated an increase in the thermodynamic performance of a booster heat pump, which was achieved by choosing the working fluid among pure and mixed fluids. The booster heat pump was integrated in an ultra-low-temperature district heating network with a forward temperature...... of 40 °C to produce domestic hot water, by heating part of the forward stream to 60 °C, while cooling the remaining part to the return temperature of 25 °C. The screening of working fluids considered 18 pure working fluids and all possible binary mixtures of these fluids. The most promising solutions...... heat supply system while being economically competitive to pure fluids....

Immunogenicity and safety of primary and booster vaccination with 2 investigational formulations of diphtheria, tetanus and Haemophilus influenzae type b antigens in a hexavalent DTPa-HBV-IPV/Hib combination vaccine in comparison with the licensed Infanrix hexa

Science.gov (United States)

Vesikari, Timo; Rivera, Luis; Korhonen, Tiina; Ahonen, Anitta; Cheuvart, Brigitte; Hezareh, Marjan; Janssens, Winnie; Mesaros, Narcisa

2017-01-01

ABSTRACT Safety and immunogenicity of 2 investigational formulations of diphtheria, tetanus and Haemophilus influenzae type b antigens of the combined diphtheria-tetanus-acellular pertussis-hepatitis B-inactivated poliomyelitis-Hib vaccine (DTPa-HBV-IPV/Hib) were evaluated in a Primary (NCT01248884) and a Booster vaccination (NCT01453998) study. In the Primary study, 721 healthy infants (randomized 1:1:1) received 3 doses of DTPa-HBV-IPV/Hib formulation A (DATAPa-HBV-IPV/Hib), or B (DBTBPa-HBV-IPV/Hib) or the licensed DTPa-HBV-IPV/Hib vaccine (Infanrix hexa, GSK; control group) at 2, 3, 4 months of age. Infants were planned to receive a booster dose at 12–15 months of age with the same formulation received in the Primary study; however, following high incidence of fever associated with the investigational formulations in the Primary study, the Booster study protocol was amended and all infants yet to receive a booster dose (N = 385) received the licensed vaccine. In the Primary study, non-inferiority of 3-dose vaccination with investigational formulations compared with the licensed vaccine was not demonstrated due to anti-pertactin failing to meet the non-inferiority criterion. Post-primary vaccination, most infants had seroprotective levels of anti-diphtheria (100% of infants), anti-tetanus antigens (100%), against hepatitis B (≥ 97.5% across groups), polyribosyl-ribitol-phosphate (≥ 88.0%) and poliovirus types 1–3 (≥ 90.5%). Seropositivity rates for each pertussis antigen were 100% in all groups. Higher incidence of fever (> 38°C) was reported in infants receiving the investigational formulations (Primary study: 75.0% [A] and 72.1% [B] vs 58.8% [control]; Booster study, before amendment: 49.4% and 46.6% vs 37.4%, respectively). The development of the investigational formulations was not further pursued. PMID:28340322

A FET based kicker for a charge booster for the TRIUMF ISAC project

International Nuclear Information System (INIS)

Barnes, M.J.; Wait, G.D.

2001-07-01

A charge booster unit is required as part of an upgrade to the ISAC facility at TRIUMF. ISAC is an isotope separator coupled to an accelerator. ISAC is presently capable of accelerating only isotopes with atomic mass up to 30. The charge booster will allow ISAC to accelerate all the masses in the periodic table. A fast kicker system has been built to study the characteristics of an existing charge booster, designed by ISN in Grenoble, to assess the suitability of using this charge booster at TRIUMF. This fast kicker will subsequently be used in the TRIUMF ISAC facility for time of flight separation of the chosen charge and to recycle the higher and lower charges back to the charge booster. This will increase the efficiency from 10% to 60%. The kicker system includes a pair of deflector plates. One plate is charged up to -3.5 kV by a PET based modulator, while the other plate is held at ground potential. The modulator consists of two stacks of FETs operating in push pull with variable output voltage, pulse width, and repetition rate from virtually DC to 52 kHz. The measured high voltage output pulse rise and fall times are 63 ns and the minimum pulse width is 350 ns. The maximum pulse width is dependent upon the repetition rate. The large dynamic range for the repetition rate and pulse width required a novel circuit design and control technique, which also resulted in an energy efficient kicker system. This paper describes the design of the kicker system and shows the results of measurements. (author)

Frequency control of RF booster cavity in TRIUMF

International Nuclear Information System (INIS)

Fong, K.; Laverty, M.

1993-01-01

A booster is used in the TRIUMF cyclotron to increase the energy gain per turn for beam orbits corresponding to energies greater than 370 MeV. It operates at 92.24 MHz, the 4 th harmonic of the cyclotron main rf, and at a nominal voltage of 150 kV. Excitation is provided by a 90 kW rf system that is phase locked to the main rf. When the main rf is interrupted due to sparking or other causes, a controller built into the low frequency source of the booster rf system disables the phase-locked loop, and reconfigures the source as a temperature stabilized oscillator operating at the last locked frequency. When the cyclotron rf is restored it usually will be at different frequency. The oscillator tunes automatically to this new frequency. The acquisition time is extended by the controller to match the response time of the mechanical tuner in the cavity

75 FR 63766 - Digital Low Power Television, Television Translator, and Television Booster Stations and Digital...

Science.gov (United States)

2010-10-18

...] Digital Low Power Television, Television Translator, and Television Booster Stations and Digital Class A... TV, TV Translator or TV Booster Station, FCC Form 346; 47 CFR 74.793(d); LPTV Out-of-Core Digital... collection requirements: 47 CFR 74.793(d) proposes that certain digital low power and TV translator stations...

SNS RING STUDY AT THE AGS BOOSTER.

Energy Technology Data Exchange (ETDEWEB)

ZHANG, S.Y.; AHRENS, L.; BEEBE-WANG, J.; BLASKIEWICZ, M.; FEDOTOV, A.; GARDNER, C.; LEE, Y.Y.; LUCCIO, A.; MALITSKY, N.; ROSER, T.; WENG, W.T.; WEI, J.; ZENO, K.; REECE, K.; WANG, J.G.

2000-06-30

During the g-2 run at the BNL AGS in early 2000, a 200 MeV storage-ring-like magnetic cycle has been set-up and tuned at the Booster in preparing for the Spallation Neutron Source (SNS) accumulator ring study. In this article, we report the progress of the machine set-up, tuning, some preliminary studies, and the future plan.

Relativistic heavy ions from the BNL [Brookhaven National Laboratory] booster medical research and technological applications

International Nuclear Information System (INIS)

Thieberger, P.

1990-05-01

The BNL Booster, now nearing completion, was designed to inject protons and heavy ions into the Alternating Gradient Synchrotron (AGS) for further acceleration. In the future, ion beams from the AGS will in turn be further accelerated in the Relativistic Heavy Ion Collider (RHIC). Given the wide range of ion masses, energies and beam intensities the Booster will generate, other important applications should be considered. Dedicated use of the Booster for such applications may be possible during limited periods. However shared use would be preferable from the points of view of availability, affordability and efficiency. While heavy ions of a given isotope are injected into the AGS, the same or other ion species from the Booster could be simultaneously delivered to a new irradiation area for treatment of patients, testing of electronic devices or other applications and research. To generate two different beam species, ion sources on both Tandem accelerators would be used; one for AGS injection and the other one for a time-sharing application. Since the beam transport from the Tandems to the Booster can not be rapidly adjusted, it will be necessary to select beams of identical magnetic rigidity. The present study was performed to determine to what extent this compatibility requirement imposes limitations on the available ion species, energies and/or intensities

Superconducting linac booster

International Nuclear Information System (INIS)

Srinivasan, B.; Betigeri, M.G.; Pandey, M.K.; Pillay, R.G.; Kurup, M.B.

1997-01-01

The report on superconducting LINAC booster, which is a joint project of Bhabha Atomic Research Centre (BARC) and Tata Institute of Fundamental Research (TIFR), brings out the work accomplished so far towards the development of the technology of superconducting LINAC to boost the energy of ions from the 14UD Pelletron. The LINAC is modular in construction with each module comprising of a helium cryostat housing four lead-plated quarter wave resonators. The resonators are superconducting for temperatures below 7.19K. An energy boost of 2 MeV/q per module is expected to be achieved. The first module and the post-tandem superbuncher have been fabricated and tested on the LINAC beam line. This report gives a summary of the technological achievements and also brings out the difficulties encountered during the R and D phase. (author)

76 FR 44821 - Digital Low Power Television, Television Translator, and Television Booster Stations and To Amend...

Science.gov (United States)

2011-07-27

...] Digital Low Power Television, Television Translator, and Television Booster Stations and To Amend Rules... Digital Low Power Television, Television Translator, and Television Booster Stations and to Amend Rules... translator facilities in the 700 MHz band. These provisions provide procedures for a primary wireless...

76 FR 72849 - Digital Low Power Television, Television Translator, and Television Booster Stations and To Amend...

Science.gov (United States)

2011-11-28

...] Digital Low Power Television, Television Translator, and Television Booster Stations and To Amend Rules... for Digital Low Power Television, Television Translator, and Television Booster Stations and to Amend... television, TV translator, and Class A television station DTV licensees''). The Commission has also revised...

PS Booster Orbit Correction

CERN Document Server

Chanel, M; Rumolo, G; Tomás, R; CERN. Geneva. AB Department

2008-01-01

At the end of the 2007 run, orbit measurements were carried out in the 4 rings of the PS Booster (PSB) for different working points and beam energies. The aim of these measurements was to provide the necessary input data for a PSB realignment campaign during the 2007/2008 shutdown. Currently, only very few corrector magnets can be operated reliably in the PSB; therefore the orbit correction has to be achieved by displacing (horizontally and vertically) and/or tilting some of the defocusing quadrupoles (QDs). In this report we first describe the orbit measurements, followed by a detailed explanation of the orbit correction strategy. Results and conclusions are presented in the last section.

Charge exchange studies with Gold ions at the Brookhaven Booster and AGS

International Nuclear Information System (INIS)

Ahrens, L.A.; Hseuh, H.C.; Roser, T.

1994-01-01

Efficient acceleration of Gold ions to ll GeV/nucleon places strong constraints on the vacuum and also on the choice of thickness and material of the necessary stripping foils. Results of a number of detailed experimental studies performed with the Gold beam at the Brookhaven Booster and AGS to determine the relevant electron stripping and pick-up probabilities are presented. Of particular interest is the lifetime of the relatively low energy, partially stripped Gold beam in the Booster and the stripping efficiency to Helium-like AU +77 for injection into the AGS

Superconducting LINAC booster for the pelletron accelerator at Bombay

International Nuclear Information System (INIS)

Pillay, R.G.; Kurup, M.B.; Jain, A.K.; Biswas, D.; Kori, S.A.; Srinivasan, B.

1989-01-01

A superconducting heavy ion linear accelerator being constructed as a booster for the 14 UD pelletron installed recently at Bombay. The work involved in this project and the progress made so far are reviewed. (author). 15 refs., 8 figs

Measuring target for the PS Booster

CERN Multimedia

1971-01-01

The measuring target for the PS Booster (originally 800 MeV, now 1.4 GeV). It measures the size of the beam by destroying all particles with amplitudes greater than the size of the fork, the position and width of which are adjustable. The plunging time is only 20 ms and the acceleration at the tip of the fork reaches 90 g. The servo-controlled linear motor is shown detached from the mechanism. See also 7602008.

Session-RPE for quantifying the load of different youth basketball training sessions.

Science.gov (United States)

Lupo, C; Tessitore, A; Gasperi, L; Gomez, Mar

2017-03-01

The aim of the study was to evaluate youth basketball training, verifying the reliability of the session-RPE method in relation to session duration (session) categories. Six male youth basketball players (age, 16.5±0.5 years; height, 195.5±6.75 cm; body mass, 93.9±10.9 kg; and body mass index, 23.6±2.8 kg.m -2 ) were monitored (HR, type and duration of workouts) during 15 (66 individual) training sessions (80±26 minutes). Edwards' HR method was used as a reference measure of internal training load (ITL); the CR-10 RPE scale was administered 30 minutes after the end of each session. The results obtained showed that all comparisons between different session durations and workout portions revealed effects in term of Edwards' ITLs except for warm-up portions. Moderate to strong relationships between Edwards' and session- RPE methods emerged for all sessions (r = .85, P sessions (r range = .79 - .95, P session durations (session-RPE to monitor the ITL, regardless of session durations and workout portions.

Pressure measurements in the AGS Booster ultra-high vacuum system

International Nuclear Information System (INIS)

Gabusi, J.; Geller, J.; Hseuh, H.C.; Mapes, M.; Stattel, P.

1992-01-01

An average pressure of mid 10 -11 Torr has been achieved and maintained in the AGS Booster ring vacuum system during its first year of operation. This ultra-high vacuum system is monitored through remote controlled Bayard-Alpert Gauges (BAGs). The characteristics of the pressure measurements with BAGs over the long cable lengths (up to 200 m) and under various accelerator operating conditions will be described. Two types of noise in the pressure readouts have been identified; the electromagnetic interference (EMI) associated with the acceleration cycles of the Booster and the environment noise associated with the temperature of the collector cables. The magnitude of the noise pickup depends on the routing of the collector cables and reaches the equivalent pressure of low 10 -9 Torr

Response of booster dose of cuban recombinant hepatitis-B vaccine in nonresponder and hyporesponder children

International Nuclear Information System (INIS)

Dahifar, H.; Mousavi, F.; Ghorbani, A.

2007-01-01

Acute hepatitis B infection can debilitate a patient for weeks and occasionally has a fatal outcome, while chronic infection is a major threat to the individual. To assess response of nonresponder and hyporesponder children to booster dose of Cuban recombinant hepatitis B vaccine. An interventional, descriptive study has been conducted on children who had been immunized with Cuban recombinant Hepatitis B vaccine and their antibody titers were <10mIU/ml (nonresponder) and 10-100mIU/ml (hyporesponder) administered booster dose of the same vaccine in their Deltoid muscles. The response of 141 children with the mean age of 1.9 years to booster dose of vaccine were 94.3% and 100% vaccines with the first and second booster dose of vaccination respectively. The anti-HBs titer in nonresponders and hyporesponders were 468+-346 and 783+-346mIU/ml respectively with significant differences between two groups (P=0.001). This study demonstrate moderately increase antibody production in the majority of vaccines with single supplementary vaccine. (author)

Beam aperture and emittance growth in the AGS-Booster

International Nuclear Information System (INIS)

Parsa, Z.

1987-01-01

The authors have developed analytical tools for calculating the variation of particle action, smear and emittance growth due to nonlinear elements in accelerators (with second order perturbation theory in two dimensions). The authors' results for the AGS-Booster is presented

Simulation of the capture process in the Fermilab Booster

International Nuclear Information System (INIS)

Stahl, S.; Ankenbrandt, C.

1987-01-01

A progress report on efforts to understand and improve adiabatic capture in the Fermilab Booster by experiment and simulation is presented. In particular, a new Rf voltage program for capture which ameliorates transverse space-charge effects is described and simulated

OPTIMAL SCHEDULING OF BOOSTER DISINFECTION IN WATER DISTRIBUTION SYSTEMS

Science.gov (United States)

Booster disinfection is the addition of disinfectant at locations distributed throughout a water distribution system. Such a strategy can reduce the mass of disinfectant required to maintain a detectable residual at points of consumption in the distribution system, which may lea...

Simulation of proton RF capture in the AGS Booster

International Nuclear Information System (INIS)

Khiari, F.Z.; Luccio, A.U.; Weng, W.T.

1988-01-01

RF capture of the proton beam in the AGS Booster has been simulated with the longitudinal phase-space tracking code ESME. Results show that a capture in excess of 95% can be achieved with multiturn injection of a chopped beam

Evaluation of a Booster Dose of Pentavalent Rotavirus Vaccine Co-Administered with Measles, Yellow Fever and Meningitis A Vaccines in 9-month-old Malian Infants.

Science.gov (United States)

Haidara, Fadima C; Tapia, Milagritos D; Sow, Samba O; Doumbia, Moussa; Coulibaly, Flanon; Diallo, Fatoumata; Traoré, Awa; Kodio, Mamoudou; Kelly, Corey L; Fitzpatrick, Meagan; Kotloff, Karen; Victor, John C; Neuzil, Kathleen

2018-04-12

Rotavirus vaccines given to infants are safe and efficacious. A booster dose of rotavirus vaccine could extend protection into the second year of life in low resource countries. We conducted an open-label, individual-randomized trial in Bamako, Mali. We assigned 600 9- to 11-month old infants to measles (MV), yellow fever (YFV), and meningococcal A conjugate vaccines with or without pentavalent rotavirus vaccine (PRV). We assessed non-inferiority of seroconversion and seroresponse rates (<10% difference) to MV, YFV and MenAV. We compared the seroresponse to PRV. Seroconversion to measles occurred in 255/261 (97.7%) and 246/252 (97.6%) of the PRV and control group; difference, 0.1% (95% CI, - 4.0 to 4.2). Seroresponse to YFV occurred in 48.1% (141/293) of the PRV group compared to 52.2% (153/293) of the control group; difference - 4.1% (95% CI, -12.2 to 4.0). A 4-fold rise in meningococcal A bactericidal titer was observed in 273/292 (93.5%) PRV recipients and 276/293 (94.2%) controls; difference, -0.7% (95% CI, - 5.2 to 3.8). Rises in anti-rotavirus IgA and IgG geometric mean concentrations were higher among PRV recipients (118 [95% CI, 91 to 154] and 364 [95% CI, 294 to 450]) compared to controls (68 [95% CI, 50 to 92] and 153 [95% CI, 114 to 207]. PRV did not interfere with MV and MenAV; this study could not rule out interference with YFV. PRV increased serum rotavirus antibody levels. NCT02286895.

Synchronization of the Zero Gradient Synchrotron (ZGS) and the fast-cycling booster II injector

International Nuclear Information System (INIS)

Rauchas, A.V.

1977-01-01

The planned method of booster injection into the ZGS requires the stacking of two booster beam bunches into the radial betatron phase space of the ZGS and necessitates precise synchronization of the two accelerators during the injection period. The requirement of maintaining independent radio-frequency (rf) steering control does not allow the frequencies of both accelerators to be locked. A synchronizer was developed which detects a coincidence zero crossing of the two rf's, anticipates the next coincidence, and at that time, generates trigger pulses for the booster extraction and ZGS injection systems. It also maintains control of the sequence in which the total phase space area of the ZGS is loaded. Synchronizer accuracy is obtained by using high speed digital logic circuits. Design considerations and system operation are discussed

Pengaruh Tandem Booster TNT Terhadap Kecepatan Detonasi Campuran Bahan Peledak Tepung Kalium Klorat, Sulfur Dan Aluminium Sebagai Bahan Peldak High Explosive

OpenAIRE

Tarigan, Tarsim

2010-01-01

There are a research on velocity of detonation explosives from Improvised Bomb with potassium chlorate, sulfur and aluminum with a composition of 65:20:15% (weight / weight), 70 mesh, galvanized pipes and containers with some blasting mechanism, starts with an explosion that ignite by a improvise detonator, factory detonator without a booster, factory detonator with a tandem booster TNT, and TNT booster modifications by adding a layer of Pb plate and make a cavity between the main booster ch...

LMFBR with booster pump in pumping loop

International Nuclear Information System (INIS)

Rubinstein, H.J.

1975-01-01

A loop coolant circulation system is described for a liquid metal fast breeder reactor (LMFBR) utilizing a low head, high specific speed booster pump in the hot leg of the coolant loop with the main pump located in the cold leg of the loop, thereby providing the advantages of operating the main pump in the hot leg with the reliability of cold leg pump operation

Control of Fermilab Booster tunes

International Nuclear Information System (INIS)

Johnson, R.P; Meisner, K.; Sandberg, B.

1977-01-01

Control of the radial and vertical tunes of the booster is implemented using ramped correction quadrupoles. Minor modifications to the power supply cards for the 48 (previously) dc correction quadrupoles allow ''the tunes'' to be continuously programmed or held constant throughout the 33 ms acceleration cycle. This capability is in addition to the usual use of these quadrupoles to be independently varied to correct for harmonic distortions in the lattice. An automatic computer program measures and displays the tunes vs. time in the cycle to monitor performance and to allow the ramps to be adjusted by the machine operator

Immunogenicity, Safety and Reactogenicity of a Booster Dose of the 10-Valent Pneumococcal Nontypeable H. influenzae Protein D Conjugate Vaccine Coadministered With DTPa-IPV-Hib in Dutch Children: A Randomized Controlled Trial.

Science.gov (United States)

van den Bergh, Menno R; Spijkerman, Judith; François, Nancy; Swinnen, Kristien; Borys, Dorota; Schuerman, Lode; Veenhoven, Reinier H; Sanders, Elisabeth A M

2016-07-01

Immune responses and safety profiles may be affected when vaccines are coadministered. We evaluated the immunogenicity, safety and reactogenicity of a booster dose of the 10-valent pneumococcal nontypeable Haemophilus influenzae protein D-conjugate (PHiD-CV; Synflorix GSK Vaccines) and DTPa-IPV-Hib (Pediacel Sanofi Pasteur MSD) when coadministered. We performed booster assessment in a randomized controlled trial in the Netherlands. Of 780 enrolled healthy infants, 774 toddlers participated in the booster phase and received (1:1:1) (1) PHiD-CV + DTPa-HBV-IPV/Hib (Infanrix hexa, GSK Vaccines), (2) PHiD-CV + DTPa-IPV-Hib, or (3) 7-valent pneumococcal conjugate vaccine (7vCRM, Prevenar/Prevnar, Pfizer, Inc.) + DTPa-IPV-Hib at 2, 3, 4 and 11-13 months old. Blood samples were taken postprimary, prebooster, 1 and 12 months postbooster. Antipneumococcal antibody responses were comparable between both PHiD-CV groups, except for serotype 18C (conjugated to tetanus toxoid). Anti-18C antibody geometric mean concentrations (GMCs) were higher when coadministered with DTPa-HBV-IPV/Hib. For each vaccine serotype, the percentages of children with antibody concentration ≥ 0.20 μg/mL were within the same ranges between PHiD-CV groups (93.8%-100%). The same was observed for the percentages of participants with opsonophagocytic activity titer ≥ 8 (90.9%-100%). When comparing both DTPa-IPV-Hib groups, postbooster antidiphtheria antibody GMCs were higher when coadministered with 7vCRM, while antitetanus and antipolyribosyl-ribitol phosphate antibody GMCs were higher with PHiD-CV coadministration. Regardless, antibody levels to these antigens were well above thresholds. Safety and reactogenicity profiles were comparable between groups. Coadministration of a booster dose of PHiD-CV and DTPa-IPV-Hib was immunogenic and well tolerated.

Post-Session Authentication

DEFF Research Database (Denmark)

Ahmed, Naveed; Jensen, Christian D.

2012-01-01

Entity authentication provides confidence in the claimed identity of a peer entity, but the manner in which this goal is achieved results in different types of authentication. An important factor in this regard is the order between authentication and the execution of the associated session....... In this paper, we consider the case of post-session authentication, where parties authenticate each other at the end of their interactive session. This use of authentication is different from session-less authentication (e.g., in RFID) and pre-session authentication (e.g., for access control.) Post......-session authentication, although a new term, is not a new concept; it is the basis of at least a few practical schemes. We, for the first time, systematically study it and present the underlying authentication model. Further, we show that an important class of problems is solvable using post-session authentication...

Nuclear power in Europe. Session 1985-86. 18. report

International Nuclear Information System (INIS)

1986-01-01

Oral and written evidence received by the Committee in 14 sessions over the months January - June 1986 from at least 20 organizations or individuals has been collected together in this one volume. Memoranda are printed and a verbatim account of the subsequent examination of witnesses is given. (UK) (author)

Influence of multiple antenatal counselling sessions on modern contraceptive uptake in Nigeria.

Science.gov (United States)

Adanikin, Abiodun I; Onwudiegwu, Uche; Loto, Olabisi M

2013-10-01

To determine the influence of multiple contraceptive counselling sessions during antenatal care on use of modern postpartum contraception. A total of 216 eligible pregnant women were randomised into antenatal and postnatal counselling groups. The 'Antenatal group' received one-to-one antenatal contraceptive counselling on several occasions while the 'Postnatal group' received a single one-to-one contraceptive counselling session at the sixth week postnatal check, as is routinely practised. All participants were contacted six months postpartum by telephone or personal visit, and questioned about their contraceptive use, if any. More women who had multiple antenatal contraceptive counselling sessions used modern contraceptive methods than those who had a single postnatal counselling session (57% vs. 35%; p = 0.002). There was also a significantly more frequent use of contraception among previously undecided patients in the Antenatal group (p = 0.014). Multiple antenatal contraceptive counselling sessions improve the use of modern postpartum contraception.

47 CFR 90.219 - Use of signal boosters.

Science.gov (United States)

2010-10-01

... to operate radio systems in the frequency bands above 150 MHz may employ signal boosters at fixed... fill in only weak signal areas and cannot extend the system's normal signal coverage area. (b) Class A... effective radiated power (ERP) of the unit to a maximum of 5 watts under all conditions. Class B broadband...

Lack of effect of a booster dose of influenza vaccine in hemodialysis patients.

Science.gov (United States)

Tanzi, Elisabetta; Amendola, Antonella; Pariani, Elena; Zappa, Alessandra; Colzani, Daniela; Logias, Franco; Perego, Angelo; Zanetti, Alessandro R

2007-08-01

To assess whether the administration of a booster dose of influenza vaccine may enhance immune response in hemodialysis patients, 58 subjects were given two doses of the 2003/2004 season influenza vaccine, 1 month apart. "European Agency for the Evaluation of Medicinal Products" (EMEA) criteria were fully met in terms of percentage of response and of mean-fold increase of hemagglutination inhibiting (HI) antibody titer, but not in terms of seroprotection rates (HI antibody titers > or =1:40). The second vaccine administration did not result in additional increase in seroprotection rate or in geometric mean titers. Protective immune response against the epidemic A/H3N2 Fujian-like strain, antigenically distant from that included in the vaccine (A/Panama/2007/99) was observed in 94.7% of vaccinees protected against the A/H3N2 vaccine strain 1 month after immunization. No adverse reactions were reported during follow-up. The study findings suggest that immune response to influenza vaccination may be suboptimal in hemodialysis patients and that the administration of an additional second dose of vaccine does not improve the humoral response.

Charge exchange injection for Nuclotron and Nuclotron booster

International Nuclear Information System (INIS)

Dinev, D.; Mikhajlov, V.

2000-01-01

The acceleration of polarized beams is between the major items in the JINR LHE's heavy ion superconducting synchrotron Nuclotron research programme. One effective way to increase the intensities of polarized deuteron beams is the application of the charge exchange injection into the Nuclotron. The paper represents the results of a new analytical description of the heavy ion stripping injection based on the Boltzmann kinetic equation. Expressions for the ion density evolution in the transverse phase plane for the emittance growth due to the elastic scattering and to energy losses in the stripping foil and for the number of successfully stored particles have been derived. These results have been applied to the stripping injection of polarized deuterons into the Nuclotron as well as to the stripping injection of heavy ions into the now under consideration Nuclotron rapid cycling booster. It has been shown that an estimated 40-fold intensity gain could be achieved for the stripping injection of polarized D - into the Nuclotron and that an effective stripping injection of light and medium ions into the booster could be realized

Simulation of the capture process in the Fermilab Booster

International Nuclear Information System (INIS)

Stahl, S.; Ankenbrandt, C.

1987-09-01

A progress report on efforts to understand and improve adiabatic capture in the Fermilab Booster by experiment and simulation is presented. In particular, a new RF voltage program for capture which ameliorates transverse space-charge effects is described and simulated. 7 refs., 4 figs

Chromatic perturbation and resonance analysis for the AGS-Booster

International Nuclear Information System (INIS)

Parsa, Z.

1987-01-01

The authors investigated the nonlinear effects with the emphasis on nonlinear resonances. They present some of their findings, (e.g. the structure resonances; stop-bandwidths, etc.) for the AGS-Booster Lattice using program HARMON. Comparison with the results obtained from the algorithm ''NONLIN'' is presented

Analysis of magnetic field measurement results for the AGS Booster magnets

International Nuclear Information System (INIS)

Bleser, E.; Thern, R.

1991-01-01

Magnetic field measurements have been made on nearly 200 conventional magnets that have been installed in the AGS Booster and its associated transfer lines. The measurements were intended to monitor the quality of the magnets being produced and to check the performance of each magnet before installation. The magnetic measurements effort led to certain improvements in the manufacturing process, which ten subsequently produced very good, very uniform magnets. The integrated dipole fields of the 36 booster dipoles are uniform to 1.5 parts in ten thousand. The magnetic measurements indicate that the quadrupoles were manufactured to an accuracy of 3 ten thousandths of an inch, which is better than we can physically measure. 3 refs., 2 figs., 4 tabs

47 CFR 101.151 - Use of signal boosters.

Science.gov (United States)

2010-10-01

... authorized to operate multiple address systems in the 928-929/952-960 MHz and 932-932.5/941-941.5 MHz bands..., or portable station(s). The booster will fill in only weak signal areas and cannot extend the system... automatic gain control circuitry which will limit the total effective radiated power (ERP) of the unit to a...

98th LHCC meeting Agenda OPEN Session and CLOSED Session

CERN Document Server

CERN. Geneva

2009-01-01

OPEN Session on Wednesday, 8 July at 9h00-11h00 in Main Auditorium, Live webcast, followed by CLOSED Session, Conference room 160-1-009 11h20-17h00. CLOSED Session continued on Thursday, 9 July at 9h00-12h30

Session-RPE for quantifying the load of different youth basketball training sessions

Directory of Open Access Journals (Sweden)

C Lupo

2016-12-01

Full Text Available The aim of the study was to evaluate youth basketball training, verifying the reliability of the session-RPE method in relation to session duration (< and ≥ 80 minutes and workout typology (reduced and high warm-up, conditioning, technical, tactical, game portions within a single session categories. Six male youth basketball players (age, 16.5±0.5 years; height, 195.5±6.75 cm; body mass, 93.9±10.9 kg; and body mass index, 23.6±2.8 kg.m-2 were monitored (HR, type and duration of workouts during 15 (66 individual training sessions (80±26 minutes. Edwards’ HR method was used as a reference measure of internal training load (ITL; the CR-10 RPE scale was administered 30 minutes after the end of each session. The results obtained showed that all comparisons between different session durations and workout portions revealed effects in term of Edwards’ ITLs except for warm-up portions. Moderate to strong relationships between Edwards’ and session- RPE methods emerged for all sessions (r = .85, P < .001, player’s sessions (r range = .79 - .95, P < .001, session durations (< 80 minutes: r = .67, P < .001; ≥ 80 minutes: r = .75, P < .001, and workout portions (r range = .78 - .89, P range = .002 - < .001. The findings indicated that coaches of youth basketball players can successfully use session-RPE to monitor the ITL, regardless of session durations and workout portions.

Hepatitis B virus vaccination booster does not provide additional protection in adolescents: a cross-sectional school-based study.

Science.gov (United States)

Chang, Yung-Chieh; Wang, Jen-Hung; Chen, Yu-Sheng; Lin, Jun-Song; Cheng, Ching-Feng; Chu, Chia-Hsiang

2014-09-23

Current consensus does not support the use of a universal booster of hepatitis B virus (HBV) vaccine because there is an anamnestic response in almost all children 15 years after universal infant HBV vaccination. We aimed to provide a booster strategy among adolescents as a result of their changes in lifestyle and sexual activity. This study comprised a series of cross-sectional serological surveys of HBV markers in four age groups between 2004 and 2012. The seropositivity rates of hepatitis B surface antigen (HBsAg) and its reciprocal antibody (anti-HBs) for each age group were collected. There were two parts to this study; age-specific HBV seroepidemiology and subgroup analysis, including effects of different vaccine types, booster response for immunogenicity at 15 years of age, and longitudinal follow-up to identify possible additional protection by HBV booster. Within the study period, data on serum anti-HBs and HBsAg in a total of 6950 students from four age groups were collected. The overall anti-HBs and HBsAg seropositivity rates were 44.3% and 1.2%, respectively. The anti-HBs seropositivity rate in the plasma-derived subgroup was significantly higher in both 15- and 18-year age groups. Overall response rate in the double-seronegative recipients at 15 years of age was 92.5% at 6 weeks following one recombinant HBV booster dose. Among the 24 recipients showing anti-HBs seroconversion at 6 weeks after booster, seven subjects (29.2%) had lost their anti-HBs seropositivity again within 3 years. Increased seropositivity rates and titers of anti-HBs did not provide additional protective effects among subjects comprehensively vaccinated against HBV in infancy. HBV booster strategy at 15 years of age was the main contributor to the unique age-related phenomenon of anti-HBs seropositivity rate and titer. No increase in HBsAg seropositivity rates within different age groups was observed. Vaccination with plasma-derived HBV vaccines in infancy provided higher

Effectiveness of Humidification with Heat and Moisture Exchanger-booster in Tracheostomized Patients.

Science.gov (United States)

Gonzalez, Isabel; Jimenez, Pilar; Valdivia, Jorge; Esquinas, Antonio

2017-08-01

The two most commonly used types of humidifiers are heated humidifiers and heat and moisture exchange humidifiers. Heated humidifiers provide adequate temperature and humidity without affecting the respiratory pattern, but overdose can cause high temperatures and humidity resulting in condensation, which increases the risk of bacteria in the circuit. These devices are expensive. Heat and moisture exchanger filter is a new concept of humidification, increasing the moisture content in inspired gases. This study aims to determine the effectiveness of the heat and moisture exchanger (HME)-Booster system to humidify inspired air in patients under mechanical ventilation. We evaluated the humidification provided by 10 HME-Booster for tracheostomized patients under mechanical ventilation using Servo I respirators, belonging to the Maquet company and Evita 4. There was an increase in the inspired air humidity after 1 h with the humidifier. The HME-Booster combines the advantages of heat and moisture exchange minimizing the negatives. It increases the amount of moisture in inspired gas in mechanically ventilated tracheostomized patients. It is easy and safe to use. The type of ventilator used has no influence on the result.

The low energy booster project status

International Nuclear Information System (INIS)

Tuttle, G.W.

1993-05-01

In order to achieve the required injection momentum, the Superconducting Super Collider (SSC) has an accelerator chain comprised of a Linear Accelerator and three synchrotrons. The Low Energy Booster (LEB) is the first synchrotron in this chain. The LEB project has made significant progress in the development of major subsystems and conventional construction. This paper briefly reviews the performance requirements of the LEB and describes significant achievements in each of the major subsystem areas. Highlighted among these achievements are the LEB foreign collaborations with the Budker Institute of Nuclear Physics (BINP) located in Novosibirsk, Russia

Modeling of the YALINA booster facility by the Monte Carlo code MONK

International Nuclear Information System (INIS)

Talamo, A.; Gohar, Y.; Kondev, F.; Kiyavitskaya, H.; Serafimovich, I.; Bournos, V.; Fokov, Y.; Routkovskaya, C.

2007-01-01

The YALINA-Booster facility has been modeled according to the benchmark specifications defined for the IAEA activity without any geometrical homogenization using the Monte Carlo codes MONK and MCNP/MCNPX/MCB. The MONK model perfectly matches the MCNP one. The computational analyses have been extended through the MCB code, which is an extension of the MCNP code with burnup capability because of its additional feature for analyzing source driven multiplying assemblies. The main neutronics arameters of the YALINA-Booster facility were calculated using these computer codes with different nuclear data libraries based on ENDF/B-VI-0, -6, JEF-2.2, and JEF-3.1.

Simulation of a programmed frequency shift near extraction from the Fermilab Booster

International Nuclear Information System (INIS)

Lucas, P.; Kerns, Q.

1987-03-01

The longitudinal phase space program ESME has been used to simulate the effects of a linear shift in RF frequency away from that appropriate for the accelerator guide field. This shift takes place in the new Booster low level RF and is used to position the particle bunches in Main Ring buckets in a reproducible fashion. Shifts in frequency are found to generate synchrotron oscillations; however, the simulations show that these can be reduced to acceptable levels by introduction of jumps in RF phase preceding the programmed frequency changes. Lowering the RF voltage near extraction from the Booster, a desirable operational feature, has also been investigated

Emergency department transport rates of children from the scene of motor vehicle collisions: do booster seats make a difference?

Science.gov (United States)

House, Darlene R; Huffman, Gretchen; Walthall, Jennifer D H

2012-11-01

Motor vehicle collisions (MVCs) are the leading cause of death and disability among children older than 1 year. Many states currently mandate all children between the ages of 4 and 8 years be restrained in booster seats. The implementation of a booster-seat law is generally thought to decrease the occurrence of injury to children. We hypothesized that appropriate restraint with booster seats would also cause a decrease in emergency department (ED) visits compared with children who were unrestrained. This is an important measure as ED visits are a surrogate marker for injury. The main purpose of this study was to look at the rate of ED visits between children in booster seats compared with those in other or no restraint systems involved in MVCs. Injury severity was compared across restraint types as a secondary outcome of booster-seat use after the implementation of a state law. A prospective observational study was performed including all children 4 to 8 years old involved in MVCs to which emergency medical services was dispatched. Ambulance services used a novel on-scene computer charting system for all MVC-related encounters to collect age, sex, child-restraint system, Glasgow Coma Scale score, injuries, and final disposition. One hundred fifty-nine children were studied with 58 children (35.6%) in booster seats, 73 children in seatbelts alone (45.2%), and 28 children (19.1%) in no restraint system. 76 children (47.7%), 74 by emergency medical services and 2 by private vehicle, were transported to the ED with no significant difference between restraint use (P = 0.534). Utilization of a restraint system did not significantly impact MVC injury severity. However, of those children who either died (n = 2) or had an on-scene decreased Glasgow Coma Scale score (n = 6), 75% (6/8) were not restrained in a booster seat. The use of booster-seat restraints does not appear to be associated with whether a child will be transported to the ED for trauma evaluation.

Standardized error severity score (ESS) ratings to quantify risk associated with child restraint system (CRS) and booster seat misuse.

Science.gov (United States)

Rudin-Brown, Christina M; Kramer, Chelsea; Langerak, Robin; Scipione, Andrea; Kelsey, Shelley

2017-11-17

Although numerous research studies have reported high levels of error and misuse of child restraint systems (CRS) and booster seats in experimental and real-world scenarios, conclusions are limited because they provide little information regarding which installation issues pose the highest risk and thus should be targeted for change. Beneficial to legislating bodies and researchers alike would be a standardized, globally relevant assessment of the potential injury risk associated with more common forms of CRS and booster seat misuse, which could be applied with observed error frequency-for example, in car seat clinics or during prototype user testing-to better identify and characterize the installation issues of greatest risk to safety. A group of 8 leading world experts in CRS and injury biomechanics, who were members of an international child safety project, estimated the potential injury severity associated with common forms of CRS and booster seat misuse. These injury risk error severity score (ESS) ratings were compiled and compared to scores from previous research that had used a similar procedure but with fewer respondents. To illustrate their application, and as part of a larger study examining CRS and booster seat labeling requirements, the new standardized ESS ratings were applied to objective installation performance data from 26 adult participants who installed a convertible (rear- vs. forward-facing) CRS and booster seat in a vehicle, and a child test dummy in the CRS and booster seat, using labels that only just met minimal regulatory requirements. The outcome measure, the risk priority number (RPN), represented the composite scores of injury risk and observed installation error frequency. Variability within the sample of ESS ratings in the present study was smaller than that generated in previous studies, indicating better agreement among experts on what constituted injury risk. Application of the new standardized ESS ratings to installation

Can a four-session biofeedback regimen be used effectively for treating children with dysfunctional voiding?

Science.gov (United States)

Sener, Nevzat Can; Altunkol, Adem; Unal, Umut; Ercil, Hakan; Bas, Okan; Gumus, Kemal; Ciftci, Halil; Yeni, Ercan

2015-01-01

To compare the outcomes of the open-ended six to ten sessions of biofeedback against a novel regime of four sessions of biofeedback to treat children with dysfunctional voiding. Patients from two centers using different methods were retrospectively analyzed. Group 1 comprised 20 patients treated with four sessions of biofeedback. Group 2 comprised 20 patients treated with six to ten sessions of biofeedback. Each group was evaluated with subjective and objective parameters pre-treatment, immediately post-treatment and 6 months post-treatment. All patients in Group 1 were treated with four sessions of biofeedback and in Group 2 the mean number of sessions was 7.35±1.30 (range 6-10). Normalized voiding flow curves after treatment were determined in 18 patients in Group 1 (90%) and 19 patients in Group 2 (95%) (p=0.553). There were seven patients (35%) in Group 1 and eight patients (40%) in Group 2 with reflux. When units were compared, there were 11 units (4 bilateral) in Group 1 and 13 units (5 bilateral) in Group 2 with reflux (p=0.747). At 6 months post-treatment, in Group 1, seven had resolved (63.6%), three had improved (27.2%) and one persisted (9.01%). In Group 2, ten had resolved (76.9%) and three had improved (23.1%) (p=0.553). Biofeedback therapy is one of the most widely used techniques in dysfunctional voiding in children. The regime of use has not been well defined, and the results of this study showed that a regime of four sessions of biofeedback therapy may be as safe and effective as the previously defined open-ended six to ten sessions.

Pertussis circulation has increased T-cell immunity during childhood more than a second acellular booster vaccination in Dutch children 9 years of age.

Directory of Open Access Journals (Sweden)

Rose-Minke Schure

Full Text Available UNLABELLED: Here we report the first evaluation of T-cell responses upon a second acellular pertussis booster vaccination in Dutch children at 9 years of age, 5 years after a preschool booster vaccination. Blood samples of children 9 years of age were studied longitudinally until 1 year after the second aP booster and compared with those after the first aP booster in children 4 and 6 years of age from a cross-sectional study. After stimulation with pertussis-vaccine antigens, Th1, Th2 and Th17 cytokine responses were measured and effector memory cells (CCR7-CD45RA- were characterized by 8-colour FACS analysis. The second aP booster vaccination at pre-adolescent age in wP primed individuals did increase pertussis-specific Th1 and Th2 cytokine responses. Noticeably, almost all T-cell responses had increased with age and were already high before the booster vaccination at 9 years of age. The enhancement of T-cell immunity during the 5 year following the booster at 4 years of age is probably caused by natural boosting due to the a high circulation of pertussis. However, the incidence of pertussis is high in adolescents and adults who have only received the Dutch wP vaccine during infancy and no booster at 4 years of age. Therefore, an aP booster vaccination at adolescence or later in these populations might improve long-term immunity against pertussis and reduce the transmission to the vulnerable newborns. TRIAL REGISTRATION: Controlled-Trials.com ISRCTN64117538.

Results from the AGS Booster transverse damper

International Nuclear Information System (INIS)

Russo, D.; Brennan, M.; Meth, M.; Roser, T.

1993-01-01

To reach the design intensity of 1.5 x 10 13 protons per pulse in the AGS Booster, transverse coupled bunch instabilities with an estimated growth rate of 1500s -1 have to be dampened. A prototype transverse damper has been tested successfully using a one turn digital delay and closed orbit suppression implemented in a programmable gate array. An updated damper, which includes an algorithm to optimize damping for a changing betatron rune, will also be presented

Session-RPE for quantifying load of different youth taekwondo training sessions.

Science.gov (United States)

Lupo, Corrado; Capranica, Laura; Cortis, Cristina; Guidotti, Flavia; Bianco, Antonino; Tessitore, Antonio

2017-03-01

The session rating of perceived exertion (session-RPE) proved to be a valuable method to quantify the internal training load (ITL) in taekwondo. However, no study validated this method in youth taekwondo athletes performing different training sessions. Thus this study aimed at evaluating the reliability of the session-RPE to monitor the ITL of prepubescent taekwondo athletes during pre-competitive (PC) and competitive (C) training sessions. Five female (age: 12.0±0.7 y; height: 1.54±0.08 m; body mass: 48.8±7.3 kg) and four male (age: 12.0±0.8 yrs; height: 1.55±0.07 m; body mass: 47.3±5.3 kg) taekwondo athletes were monitored during 100 individual sessions (PC: N.=33; C: N.=67). The Edwards' HR method was used as reference measure of ITL; the CR-10 RPE scale was administered at 1- and 30-minutes from the end of each session. No difference for gender emerged. The ITLs of C (Edwards: 228±40 arbitrary units, AU) resulted higher than that of PC (192±26 AU; P=0.04). Although all training typologies and data collections achieved significant correlations between Edwards' and session-RPE methods, a large relationship (r =0.71, Psessions evaluated at 30 minutes of the recovery phases. Findings support coaches of prepubescent taekwondo athletes to successfully use session-RPE to monitor the ITL of different training typologies. However, PC training evaluated at 30 minutes of the recovery phase represents the best condition for a highly reliable ITL perception.

Booster HBV vaccination; is it really necessary? | Alavian | Egyptian ...

African Journals Online (AJOL)

Egyptian Journal of Pediatric Allergy and Immunology (The). Journal Home · ABOUT THIS JOURNAL · Advanced Search · Current Issue · Archives · Journal Home > Vol 9, No 2 (2011) >. Log in or Register to get access to full text downloads. Username, Password, Remember me, or Register. Booster HBV vaccination; is it ...

Assessing treatment integrity in cognitive-behavioral therapy: comparing session segments with entire sessions.

Science.gov (United States)

Weck, Florian; Grikscheit, Florian; Höfling, Volkmar; Stangier, Ulrich

2014-07-01

The evaluation of treatment integrity (therapist adherence and competence) is a necessary condition to ensure the internal and external validity of psychotherapy research. However, the evaluation process is associated with high costs, because therapy sessions must be rated by experienced clinicians. It is debatable whether rating session segments is an adequate alternative to rating entire sessions. Four judges evaluated treatment integrity (i.e., therapist adherence and competence) in 84 randomly selected videotapes of cognitive-behavioral therapy for major depressive disorder, social anxiety disorder, and hypochondriasis (from three different treatment outcome studies). In each case, two judges provided ratings based on entire therapy sessions and two on session segments only (i.e., the middle third of the entire sessions). Interrater reliability of adherence and competence evaluations proved satisfactory for ratings based on segments and the level of reliability did not differ from ratings based on entire sessions. Ratings of treatment integrity that were based on entire sessions and session segments were strongly correlated (r=.62 for adherence and r=.73 for competence). The relationship between treatment integrity and outcome was comparable for ratings based on session segments and those based on entire sessions. However, significant relationships between therapist competence and therapy outcome were only found in the treatment of social anxiety disorder. Ratings based on segments proved to be adequate for the evaluation of treatment integrity. The findings demonstrate that session segments are an adequate and cost-effective alternative to entire sessions for the evaluation of therapist adherence and competence. Copyright © 2014. Published by Elsevier Ltd.

Power Supply of the Booster Magnets for the ILSF Synchrotron

Directory of Open Access Journals (Sweden)

O Ahmadi

2017-08-01

Full Text Available The Iranian Light Source Facility (ILSF booster main specifications including 250 ms ramp up, 2Hz repetition rate, and quasi-sinusoidal wave shape, up to this point have been the basis for calculations. Each family of magnets including Dipole, Quadrupole and Sextupoles will feed by individual power supply. In order to maintain constant transverse tunes and chromaticity while the beam is accelerated, quadrupole and sextupole magnet currents must closely track the current in the dipole magnets. In booster rings, feeding the high inductance load, tracking of Quadrupole and sextupole magnets, reducing output current fluctuation and having a precise high bandwidth current regulation system are particular challenges. In order to meet the requirements, it is necessary to have a fully digital controller to achieve a fast regulation system. The prototype power supply and its test results are described in this paper  

The AGS Booster vacuum systems

International Nuclear Information System (INIS)

Hseuh, H.C.

1989-01-01

The AGS Booster is a synchrotron for the acceleration of both protons and heavy ions. The design pressure of low 10 -11 mbar is required to minimize beam loss of the partially stripped heavy ions. To remove contaminants and to reduce outgassing, the vacuum chambers and the components located in them will be chemically cleaned, vacuum fired, baked then treated with nitric oxide. The vacuum sector will be insitu baked to a minimum of 200 degree C and pumped by the combination of sputter ion pumps and titanium sublimation pumps. This paper describes the design and the processing of this ultra high vacuum system, and the performance of some half-cell vacuum chambers. 9 refs., 7 figs

REDUCING THE BOOSTER STATIONS ENERGY CONSUMPTION BY WAY OF ELIMINATING OVERPRESSURE IN THE WATER SUPPLY NETWORK

Directory of Open Access Journals (Sweden)

G. N. Zdor

2015-01-01

Full Text Available The energy efficiency improvement of the city housing-and-utilities infrastructure and watersupply and water-disposal systems poses an occurrent problem. The water-supply systems energy consumption sizable share falls on the pump plants. The article deals with the issues of the operating regime management of the existing booster stations equipped with a group of pumping units regulated with frequency converters. One of the optimization directions of their energy consumption is the reduction of over-pressure in the water-distribution network and its sustentation within the regulatory values. The authors offer the structure and methodology of the data collection-and-analysis automated system utilization for revealing and eliminating the overpressure in the water-supply network. This system is designed for the group management of booster-stations operating regimes on the ground of data obtained from the pressure controlling devices at the consumers. The data exchange in the system is realized via GSM.The paper presents results of the tests carried out at the booster stations in some major cities of the Republic of Belarus. The authors analyze dependence of overpressure in the network on the methods of the plant output pressure sustentation (daily graph or constant pressure. The authors study the elimination effect of over-pressure in the water distribution network on changing the booster station pumping units operation regimes. The study shows that eliminating over pressure in the water distributing network leads to lowering the booster station pressure. This in its turn decreases its energy consumption by 15–20 % depending on the over pressure fixed level.

Beam position monitoring in the AGS Linac to Booster transfer line

International Nuclear Information System (INIS)

Shea, T.J.; Brodowski, J.; Witkover, R.

1991-01-01

A beam position monitor system has been developed and used in the commissioning of Brookhaven's Linac to Booster transfer line. This line transports a chopped, RF modulated H- beam from the 200 MeV Linac to the AGS Booster. Over a 15dB dynamic range in beam current, the position monitor system provides a real-time, normalized position signal with an analog bandwidth of about 20 MHz. Seven directional coupler style pickups are installed in the line with each pickup sensing both horizontal and vertical position. Analog processing electronics are located in the tunnel and incorporate the amplitude modulation to phase modulation normalization technique. To avoid interference from the 200 MHz linac RF system, processing is performed at 400 MHz. This paper provides a system overview and report results from the commissioning experience

Electron cooling system in the booster synchrotron of the HIAF project

Energy Technology Data Exchange (ETDEWEB)

Mao, L.J., E-mail: maolijun@impcas.ac.cn [Institute of Modern Physics, Chinese Academy of Sciences, Lanzhou 730000 (China); Yang, J.C.; Xia, J.W.; Yang, X.D.; Yuan, Y.J.; Li, J.; Ma, X.M.; Yan, T.L.; Yin, D.Y.; Chai, W.P.; Sheng, L.N. [Institute of Modern Physics, Chinese Academy of Sciences, Lanzhou 730000 (China); Shen, G.D.; Zhao, H.; Tang, M.T. [Institute of Modern Physics, Chinese Academy of Sciences, Lanzhou 730000 (China); Graduate University of Chinese Academy of Sciences, Beijing 100049 (China)

2015-06-21

The High Intensity heavy ion Accelerator Facility (HIAF) is a new accelerator complex under design at the Institute of Modern Physics (IMP). The facility is aiming at the production of high intensity heavy ion beams for a wide range of experiments in high energy density physics, nuclear physics, atomic physics and other applications. It consists of a superconducting electron-cyclotron-resonance ion source and an intense proton ion source, a linear accelerator, a 34 Tm booster synchrotron ring, a 43 Tm multifunction compression synchrotron ring, a 13 Tm high precision spectrometer ring and several experimental terminals. A magnetized electron cooling device is supposed to be used in the booster ring for decreasing the transverse emittance of injected beams. The conceptual design and main parameters of this cooler are presented in this paper.

Development of hydraulic brake actuator for active brake control; Active brake seigyoyo yuatsu booster no kaihatsu

Energy Technology Data Exchange (ETDEWEB)

Konishi, Y; Hattori, M. Sugisawa, M.; Nishii, M [Aisin Seiki Co. Ltd., Aichi (Japan)

1997-10-01

Recently, application of active brake control systems of the vehicle are increasing. (Vehicle stability control, Panic brake assist ) We have developed a new hydraulic brake actuator for active brake control systems. New hydraulic brake actuator is composed of the three parts. (Hydraulic booster unit, Power supply unit, Control valve unit) This report describes the construction of the new hydraulic booster unit. 2 refs., 10 figs.

Design and testing of the AGS Booster BPM detector

International Nuclear Information System (INIS)

Thomas, R.; Ciardullo, D.J.; Van Zwienen, W.

1991-01-01

The AGS Booster beam position monitor system must accurately measure the position of beams and bunches over a wide range of intensity. The frequency of operation must also cover a wide range (600 kHz to 4.2 MHz) since the Booster accelerates both protons and heavy ions. Split-cylinder electrodes were chosen to monitor the position of the beam because of their good low frequency response and high linearity. The need to accelerate low-energy partially-stripped heavy ions requires the pick-up electrodes (PUEs) to operate in a 3 x 10 -11 torr vacuum. The PUEs are to measure the beam position to an absolute accuracy of ±0.5 mm and must therefore be mechanically stable despite the requirements that they be vacuum fired at 950 degree C and baked periodically to 300 degree C. This presentation describes both the mechanical design of the PUEs and the automated test procedure used to ensure the stability, accuracy, and linearity of each unit. 3 refs., 5 figs

Locomotor Training and Strength and Balance Exercises for Walking Recovery After Stroke: Response to Number of Training Sessions.

Science.gov (United States)

Rose, Dorian K; Nadeau, Stephen E; Wu, Samuel S; Tilson, Julie K; Dobkin, Bruce H; Pei, Qinglin; Duncan, Pamela W

2017-11-01

Evidence-based guidelines are needed to inform rehabilitation practice, including the effect of number of exercise training sessions on recovery of walking ability after stroke. The objective of this study was to determine the response to increasing number of training sessions of 2 interventions-locomotor training and strength and balance exercises-on poststroke walking recovery. This is a secondary analysis of the Locomotor Experience Applied Post-Stroke (LEAPS) randomized controlled trial. Six rehabilitation sites in California and Florida and participants' homes were used. Participants were adults who dwelled in the community (N=347), had had a stroke, were able to walk at least 3 m (10 ft) with assistance, and had completed the required number of intervention sessions. Participants received 36 sessions (3 times per week for 12 weeks), 90 minutes in duration, of locomotor training (gait training on a treadmill with body-weight support and overground training) or strength and balance training. Talking speed, as measured by the 10-Meter Walk Test, and 6-minute walking distance were assessed before training and following 12, 24, and 36 intervention sessions. Participants at 2 and 6 months after stroke gained in gait speed and walking endurance after up to 36 sessions of treatment, but the rate of gain diminished steadily and, on average, was very low during the 25- to 36-session epoch, regardless of treatment type or severity of impairment. Results may not generalize to people who are unable to initiate a step at 2 months after stroke or people with severe cardiac disease. In general, people who dwelled in the community showed improvements in gait speed and walking distance with up to 36 sessions of locomotor training or strength and balance exercises at both 2 and 6 months after stroke. However, gains beyond 24 sessions tended to be very modest. The tracking of individual response trajectories is imperative in planning treatment. Published by Oxford University

Low Energy Electron Cooler for NICA Booster

CERN Document Server

Denisov, A P

2017-01-01

BINP has developed an electron cooler to increase the ion accumulation efficiency in the NICA (Nuclotron-based Ion Collider fAcility) heavy ion booster (JINR, Dubna). Adjustment of the cooler magnetic system provides highly homogeneous magnetic field in the cooling section B trans/B long ≤ 4∙10-5 which is vital for efficient electron cooling. First experiments with an electron beam performed at BINP demonstrated the target DC current of 500 mA and electron energy 6 keV.

Position pickup of the PS Booster

CERN Multimedia

CERN PhotoLab

1975-01-01

The beam position around the 4 rings of the PS Booster (originally 800 MeV, now 1.4 GeV), is measured with electrostatic pickups (PU). They consist of a ceramic cylinder forming part of the vacuum chamber, and, in order to save space, they are located inside the multipole lenses. The inside of the ceramic is coated with a metallic layer, into which the form of the electrodes was cut by computer-controlled micro-sandblasting. Each PU has a pair of horizontal and a pair of vertical electrodes, as well as a separate intensity-sensing circular electrode.

Formal description of the OSI session layer: session service

NARCIS (Netherlands)

van Sinderen, Marten J.; van Eijk, P.H.J.; Vissers, C.A.; Diaz, M.

1989-01-01

The LOTOS formal description of the OSI session service is presented on basis of specification samples from the full description, giving account of how specification styles and session service architectural elements are reflected in the description. Both information (data types) and process

Ultra-short-course booster is effective in recurrent grass pollen-induced allergic rhinoconjunctivitis.

Science.gov (United States)

Pfaar, O; Lang, S; Pieper-Fürst, U; Astvatsatourov, A; Gerich, F; Klimek, L; Kramer, M F; Reydelet, Y; Shah-Hosseini, K; Mösges, R

2018-01-01

A relevant proportion of allergic rhinoconjunctivitis (ARC) patients experience recurrent symptoms after successfully completing allergen immunotherapy (AIT). This prospective, controlled, noninterventional study used internationally standardized instruments to determine the clinical effects of a preseasonal, ultra-short-course booster AIT on clinical outcome parameters. This two-arm study included patients aged ≥12 years with recurrent grass pollen-induced seasonal AR who had completed a successful course of any grass pollen AIT at least 5 years before enrolment. Overall, 56 patients received one preseasonal short-course booster AIT using tyrosine-absorbed grass pollen allergoids containing the adjuvant monophosphoryl lipid A (MPL ® ); 51 control patients received symptomatic medication. The combined symptom and medication score (CSMS) was recorded in the (peak) grass pollen season. Furthermore, concomitant (antiallergic) medication use, the patients' state of health, Mini Rhinoconjunctivitis Quality of Life Questionnaire (MiniRQLQ) results and safety/tolerability of the treatment were assessed. The CSMS in the peak grass pollen season was significantly lower in the booster AIT group (Δ=38.4%, Pallergoids containing the adjuvant MPL ® effectively prevents re-occurrence of symptoms in patients with grass pollen-induced ARC. © 2017 The Authors. Allergy Published by John Wiley & Sons Ltd.

Preparations for Upgrading the RF Systems of the PS Booster

CERN Document Server

Albright, Simon; Shaposhnikova, Elena

2016-01-01

The accelerators of the LHC injector chain need to be upgraded to provide the HL-LHC beams. The PS Booster, the first synchrotron in the LHC injection chain, uses three different RF systems (first, second and up to tenth harmonic) in each of its four rings. As part of the LHC Injector Upgrade the current ferrite RF systems will be replaced with broadband Finemet cavities, increasing the flexibility of the RF system. A Finemet test cavity has been installed in Ring 4 to investigate its effect on machine performance, especially beam stability, during extensive experimental studies. Due to large space charge impedance Landau damping is lost through most of the cycle in single harmonic operation, but is recovered when using the second harmonic and controlled longitudinal emittance blow-up. This paper compares beam parameters during acceleration with and without the Finemet test cavity. Comparisons were made using beam measurements and simulations with the BLonD code based on a full PS Booster impedance model. Thi...

Perpendicular biased ferrite tuned RF cavity for the TRIUMF KAON Factory booster ring

International Nuclear Information System (INIS)

Poirier, R.L.; Enegren, T.; Haddock, C.

1989-03-01

The rf cavity for the booster ring requires a frequency swing of 46 MHz to 62 MHz at a repetition rate of 50 Hz. The possibility of using the LANL booster cavity design with a yttrium garnet ferrite tuner biased perpendicular to the rf field, in the longitudinal direction, is being investigated. In order to minimize the stray magnetic biasing field on the beam axis, an alternative scheme similar to the design being proposed for the LANL main ring cavity in which the ferrite is perpendicular biased in the radial direction, is being considered. The behaviour of the rf cavity and the magnetizing circuit for both designs are discussed

A new one-man submarine is tested as vehicle for solid rocket booster retrieval

Science.gov (United States)

2000-01-01

- The one-man submarine known as DeepWorker 2000 is tested in Atlantic waters near Cape Canaveral, Fla. Nearby are divers; inside the sub is the pilot, Anker Rasmussen. The sub is being tested on its ability to duplicate the sometimes hazardous job United Space Alliance (USA) divers perform to recover the expended boosters in the ocean after a launch. The boosters splash down in an impact area about 140 miles east of Jacksonville and after recovery are towed back to KSC for refurbishment by the specially rigged recovery ships. DeepWorker 2000 will be used in a demonstration during retrieval operations after the upcoming STS-101 launch. The submarine pilot will demonstrate capabilities to cut tangled parachute riser lines using a manipulator arm and attach a Diver Operator Plug to extract water and provide flotation for the booster. DeepWorker 2000 was built by Nuytco Research Ltd., North Vancouver, British Columbia. It is 8.25 feet long, 5.75 feet high, and weighs 3,800 pounds. USA is a prime contractor to NASA for the Space Shuttle program.

Design and optimization of a large flow rate booster pump in SWRO energy recovery system

International Nuclear Information System (INIS)

Lai, Z N; Wu, P; Wu, D Z; Wang, L Q

2013-01-01

Seawater reverse osmosis (SWRO) is a high energy-consumption industry, so energy efficiency is an important issue. Energy recovery systems, which contain a pressure exchanger and a booster pump, are widely used in SWRO plants. As a key part of energy recovery system, the difficulty of designing booster pumps lies in high inlet pressure, high medium causticity and large flow rate. High inlet pressure adds difficulties to seal design, and large flow rate and high efficiency requirement bring high demand for hydraulic design. In this paper, a 625 m 3 /h booster pump is designed and optimized according to the CFD (Computational Fluid Dynamics) simulation results. The impeller and volute is well designed, a new type of high pressure mechanical seal is applied and axial force is well balanced. After optimization based on blade redesign, the efficiency of the pump was improved. The best efficiency reaches more than 85% at design point according to the CFD simulation result

Design and optimization of a large flow rate booster pump in SWRO energy recovery system

Science.gov (United States)

Lai, Z. N.; Wu, P.; Wu, D. Z.; Wang, L. Q.

2013-12-01

Seawater reverse osmosis (SWRO) is a high energy-consumption industry, so energy efficiency is an important issue. Energy recovery systems, which contain a pressure exchanger and a booster pump, are widely used in SWRO plants. As a key part of energy recovery system, the difficulty of designing booster pumps lies in high inlet pressure, high medium causticity and large flow rate. High inlet pressure adds difficulties to seal design, and large flow rate and high efficiency requirement bring high demand for hydraulic design. In this paper, a 625 m3/h booster pump is designed and optimized according to the CFD (Computational Fluid Dynamics) simulation results. The impeller and volute is well designed, a new type of high pressure mechanical seal is applied and axial force is well balanced. After optimization based on blade redesign, the efficiency of the pump was improved. The best efficiency reaches more than 85% at design point according to the CFD simulation result.

Project of Ariane 5 LV family advancement by use of reusable fly-back boosters (named “Bargouzine”)

Science.gov (United States)

Sumin, Yu.; Bonnal, Ch.; Kostromin, S.; Panichkin, N.

2007-12-01

The paper concerns possible concept variants of a partially reusable Heavy-Lift Launch Vehicle derived from the advanced basic launcher (Ariane-2010) by means of substitution of the EAP Solid Rocket Boosters for a Reusable Starting Stage consisting two Liquid-propellant Reusable Fly-Back Boosters called "Bargouzin". This paper describes the status of the presently studied RFBB concepts during its three phases. The first project phase was dedicated to feasibility expertise of liquid-rocket reusable fly-back boosters ("Baikal" type) utilization for heavy-lift space launch vehicle. The design features and main conclusions are presented. The second phase has been performed with the purpose of selection of preferable concept among the alternative ones for the future Ariane LV modernization by using RFBB instead of EAP Boosters. The main requirements, logic of work, possible configuration and conclusion are presented. Initial aerodynamic, ballistic, thermoloading, dynamic loading, trade-off and comparison analysis have been performed on these concepts. The third phase consists in performing a more detailed expertise of the chosen LV concept. This part summarizes some of the more detailed results related to flight performance, system mass, thermoprotection system, aspects of technologies, ground complex modification, comparison analyses and conclusion.

A Linac afterburner to supercharge the Fermilab booster

International Nuclear Information System (INIS)

Ankenbrandt M, Charles email = popovic@fnal.gov

2002-01-01

A Linac Afterburner is proposed to raise the energy of the beam injected into the Femrilab Booster from 400 MeV to about 600 MeV, thereby alleviating the longitudinal and transverse space-charge effects at low energy that currently limit its performance. The primary motivation is to increase the integrated luminosity of the Tevatron Collider in Run II, but other future programs would also recap substantial benefits. The estimated cost is $23M

Implementation of electron beam position measurement algorithm and embedded web server using MCS-51 microcontroller for Booster Synchrotron

International Nuclear Information System (INIS)

Shrivastava, B.B.; Chouhan, Manish; Puntambekar, T.A.; Tiwari, A.N.

2015-01-01

The Booster Synchrotron at RRCAT caters as Injector Machine for Indus-1 and Indus-2 with the repetition rate of 1Hz. In Booster Synchrotron, energy of electron bunches are increased from 20 MeV to 450 MeV (in ∼ 280 ms) and 550 MeV (in ∼ 340 ms ) for Indus-1 and Indus-2 respectively. An algorithm for microcontroller based beam position measurement system has been developed for the Booster Synchrotron to measure the fast changes in the beam position of electron bunches during energy ramping. In this paper, software implementation in microcontroller and its optimization to achieve beam position update rate of 1 kHz is discussed. (author)

Numerical model for thermoeconomic diagnosis in commercial transcritical/subcritical booster refrigeration systems

International Nuclear Information System (INIS)

Ommen, Torben; Elmegaard, Brian

2012-01-01

Highlights: ► A transcritical booster refrigeration plant is modelled. ► We examine changes in cost flow at different operation parameters. ► The use of characteristic curves for diagnosis is studied. - Abstract: Transcritical/subcritical booster refrigeration systems are increasingly installed and used in Danish supermarkets. The systems operate in both transcritical and subcritical conditions dependent on the heat rejection performance and the ambient conditions. The plant consists of one refrigerant cycle supplying refrigerant for evaporators in both chilled and frozen display cases. In the paper, thermoeconomic theory is used to establish the cost of cooling at each individual temperature level based on operating costs. With a high amount of operating systems, faulty operation becomes an economic, and environmental, interest. A general solution for evaluation of these systems is considered, with the objective to reduce cost and power consumption of malfunctioning equipment in operation. An analysis of the use of thermoeconomic diagnosis methods is required, as these methods may prove applicable. To accommodate the analysis, a numerical model of a transcritical booster refrigeration plant is considered in this paper. Additionally the characteristic curves method is applied to the high pressure compressor unit of the refrigeration plant. The approach successfully determine whether an anomaly is intrinsic or induced in the component when no uncertainties are introduced in the steady state model.

A randomized controlled trial of a resilience-based intervention on psychosocial well-being of children affected by HIV/AIDS: Effects at 6- and 12-month follow-up.

Science.gov (United States)

Li, Xiaoming; Harrison, Sayward E; Fairchild, Amanda J; Chi, Peilian; Zhao, Junfeng; Zhao, Guoxiang

2017-10-01

Global literature suggests that resilience-based interventions may yield improvements in psychosocial well-being for vulnerable children, but limited data are available regarding the efficacy of such interventions among children affected by parental HIV/AIDS. To evaluate initial efficacy of a multi-level resilience-based intervention among children affected by parental HIV/AIDS in China in improving children's psychosocial well-being and resilience-related outcomes. Seven hundred-ninety children, 6-17 years of age, were recruited from rural China. Children were either AIDS orphans or were living with one or two parents infected with HIV/AIDS. Children and primary caregivers were randomly assigned to participate in a 4-arm trial to evaluate the Child-Caregiver-Advocacy Resilience (ChildCARE) intervention. This resilience-based psychosocial intervention provides programming at three levels (child, caregiver, community). Survey data were collected at baseline, 6-months, and 12-months in order to examine efficacy of the child-only and child + caregiver arms in improving children's psychological resilience. Intervention groups displayed improvements in several resilience-related outcomes at 6- and 12-month follow-ups, including self-reported coping, hopefulness, emotional regulation, and self-control. The child-only intervention arm showed some fading of intervention effects by 12-months. Preliminary findings suggest that the ChildCARE intervention is efficacious in promoting psychosocial well-being of children affected by parental HIV/AIDS in rural China. Targeting both children and caregivers for psychosocial intervention may be effective in improving children's resilience. Additional evaluation and modifications, including the inclusion of booster sessions, should be considered to further strengthen the program. Copyright © 2017 Elsevier Ltd. All rights reserved.

The injection and extraction of SSRF booster

International Nuclear Information System (INIS)

Li Yuan; Li Haohu; Liu Guimin; Li Deming

2008-01-01

The layout of injection and extraction system were introduced in this paper. The horizontal and vertical injection acceptance are about 23 πmm·mrad and 37 πmm·mrad, respectively, while emittance of the injected beam is 9 πmm·mrad (3σ). This ensures the high injection efficiency. Three slow kickers can form a good bump. The inside position of the entrance of septum is set to 15 mm, where the bumped beam and the extraction beam are 10 mm and 22 mm, respectively, far from the booster central orbit. (authors)

The PS Booster's ejection kicker: full house.

CERN Multimedia

CERN PhotoLab

1971-01-01

The modules of the Booster's four-storied full-aperture kicker pretty much fill their vacuum tank (front cover removed). In the original 800 MeV version, the delay-type modules were pulsed at 30 kV from a Pulse-Forming-Network (PFN), yielding a field risetime as short as 60 ns. The fieldstrength was 0.1 T at a current of 1200 A. The modules are made from steel plates and ferrite slabs. The ferrite's high initial outgassing rate presented a serious vacuum problem for a long time.

Multipole stack for the 4 rings of the PS Booster

CERN Multimedia

CERN PhotoLab

1976-01-01

The PS Booster (originally 800 MeV, now 1.4 GeV) saw first beam in 1972, routine operation began in 1973. The strive for ever higher intensities required the addition of multipoles. Manufacture of 8 stacks of multipoles was launched in 1974, for installation in 1976. For details, see 7511120X.

Evaluation of a training program to assist care staff to better recognize and manage depression among palliative care patients and their families.

Science.gov (United States)

McCabe, Marita R P; Goldhammer, Denisa; Mellor, David; Hallford, David; Davison, Tanya

2012-01-01

This study was designed to evaluate the effectiveness of a training program to improve the knowledge, attitudes, and self-efficacy of palliative care staff and thus enable them to better detect and manage depression among palliative care patients and their families. Participants were 90 professional carers who completed a four-session training program. Knowledge, attitudes, self-efficacy, and barriers to working with depressed patients were assessed preintervention, post-intervention, and at a three-month follow-up. The results demonstrated that compared to the control group, the intervention group had improved in all of these areas. Improvements were maintained at the three-month follow-up in all areas except attitudes. The results of this study indicate the importance of training in managing depression among palliative care staff. Booster sessions will likely be needed to ensure that training program gains are maintained.

Post-Session Authentication

OpenAIRE

Ahmed , Naveed; Jensen , Christian ,

2012-01-01

Part 1: Full Papers; International audience; Entity authentication provides confidence in the claimed identity of a peer entity, but the manner in which this goal is achieved results in different types of authentication. An important factor in this regard is the order between authentication and the execution of the associated session. In this paper, we consider the case of post-session authentication, where parties authenticate each other at the end of their interactive session. This use of a...

RF field control for KAON Factory booster cavities

International Nuclear Information System (INIS)

Craig, S.T.; de Jong, M.S.

1990-11-01

A conceptual design is developed for control of the KAON Factory Booster rf accelerating fields. This design addresses control of cavity: tuning, voltage amplitude, and voltage phase angle. Time-domain simulations were developed to evaluated the proposed controllers. These simulations indicated that adequate tuning performance can be obtained with the combination of adaptive feed-forward and proportional feedback control. Voltage amplitude and voltage phase can be adequately controlled using non-adaptive feedforward and proportional feedback control

Beam Diagnosis and Lattice Modeling of the Fermilab Booster

International Nuclear Information System (INIS)

Huang, Xiaobiao

2005-01-01

A realistic lattice model is a fundamental basis for the operation of a synchrotron. In this study various beam-based measurements, including orbit response matrix (ORM) and BPM turn-by-turn data are used to verify and calibrate the lattice model of the Fermilab Booster. In the ORM study, despite the strong correlation between the gradient parameters of adjacent magnets which prevents a full determination of the model parameters, an equivalent lattice model is obtained by imposing appropriate constraints. The fitted gradient errors of the focusing magnets are within the design tolerance and the results point to the orbit offsets in the sextupole field as the source of gradient errors. A new method, the independent component analysis (ICA) is introduced to analyze multiple BPM turn-by-turn data taken simultaneously around a synchrotron. This method makes use of the redundancy of the data and the time correlation of the source signals to isolate various components, such as betatron motion and synchrotron motion, from raw BPM data. By extracting clean coherent betatron motion from noisy data and separates out the betatron normal modes when there is linear coupling, the ICA method provides a convenient means to measure the beta functions and betatron phase advances. It also separates synchrotron motion from the BPM samples for dispersion function measurement. The ICA method has the capability to separate other perturbation signals and is robust over the contamination of bad BPMs. The application of the ICA method to the Booster has enabled the measurement of the linear lattice functions which are used to verify the existing lattice model. The transverse impedance and chromaticity are measured from turn-by-turn data using high precision tune measurements. Synchrotron motion is also observed in the BPM data. The emittance growth of the Booster is also studied by data taken with ion profile monitor (IPM). Sources of emittance growth are examined and an approach to cure

Yalina booster subcritical assembly performance with low enriched uranium fuel

International Nuclear Information System (INIS)

Talamo, Alberto; Gohar, Yousry

2011-01-01

The YALINA Booster facility is a subcritical assembly located in Minsk, Belarus. The facility has special features that result in fast and thermal neutron spectra in different zones. The fast zone of the assembly uses a lead matrix and uranium fuels with different enrichments: 90% and 36%, 36%, or 21%. The thermal zone of the assembly contains 10% enriched uranium fuel in a polyethylene matrix. This study discusses the performance of the three YALINA Booster configurations with the different fuel enrichments. In order to maintain the same subcriticality level in the three configurations, the number of fuel rods in the thermal zone is increased as the uranium fuel enrichment in the fast zone is decreased. The maximum number of fuel rods that can be loaded in the thermal zone is about 1185. Consequently, the neutron multiplication of the configuration with 21% enriched uranium fuel in the fast zone is enhanced by changing the position of the boron carbide and the natural uranium absorber rods, located between the fast and the thermal zones, to form an annular rather than a square arrangement. (author)

Yalina booster subcritical assembly performance with low enriched uranium fuel

Energy Technology Data Exchange (ETDEWEB)

Talamo, Alberto; Gohar, Yousry, E-mail: alby@anl.gov [Argonne National Laboratory, Lemont, IL (United States)

2011-07-01

The YALINA Booster facility is a subcritical assembly located in Minsk, Belarus. The facility has special features that result in fast and thermal neutron spectra in different zones. The fast zone of the assembly uses a lead matrix and uranium fuels with different enrichments: 90% and 36%, 36%, or 21%. The thermal zone of the assembly contains 10% enriched uranium fuel in a polyethylene matrix. This study discusses the performance of the three YALINA Booster configurations with the different fuel enrichments. In order to maintain the same subcriticality level in the three configurations, the number of fuel rods in the thermal zone is increased as the uranium fuel enrichment in the fast zone is decreased. The maximum number of fuel rods that can be loaded in the thermal zone is about 1185. Consequently, the neutron multiplication of the configuration with 21% enriched uranium fuel in the fast zone is enhanced by changing the position of the boron carbide and the natural uranium absorber rods, located between the fast and the thermal zones, to form an annular rather than a square arrangement. (author)

Reproducibility of skeletal muscle vasodilatation responses to Stroop mental challenge over repeated sessions.

Science.gov (United States)

Hamer, Mark; Boutcher, Yati N; Park, Young; Boutcher, Stephen H

2006-08-01

Skeletal muscle blood flow responses to stress have implications for psychobiological disease pathways. An important assumption underlying psychophysiological studies relating stress reactivity with disease risk is that individuals are characterized by stable response profiles that can be reliably assessed using acute psychophysiological stress testing. We examined the reproducibility of forearm vasodilatation, blood pressure, and cardiac responses to a 2 min Stroop mental challenge over two repeated stress sessions that were on average 3.6 months apart. Participants were 21 healthy men and women (aged 21.8+/-3.7 years). Vasodilatation, blood pressure and heart rate responses displayed no habituation between sessions, although there was significantly greater cardiac parasympathetic involvement during the second testing session. Significant test-retest correlations between the sessions were observed for both forearm blood flow and heart rate reactivity. These findings demonstrate skeletal muscle vasodilatation responses to repeated stress are robust, so may be a useful psychophysiological indicator in studies of stress reactivity and disease risk.

Effect of oral booster vaccination of rainbow trout against Yersinia ruckeri depends on type of primary immunization

DEFF Research Database (Denmark)

Jaafar, Rzgar M.; Al-Jubury, Azmi; Dalsgaard, Inger

2017-01-01

provided as dip (most effective), bath (less effective) or orally (least effective). Oral immunization may be used as booster after dip but applied as a single oral application it induced merely a slight and statistically non-significant response. It is noteworthy that primary oral immunization followed...... already primed by one of these vaccination methods. Oral vaccination of trout (administering vaccine in feed) is an even more convenient way of presenting antigen to the fish but the effect of an oral booster has not previously been described in detail. The present work describes to what extent protection...... by an oral booster vaccination showed a trend for an even weaker response. It should be investigated if continued exposure to a low antigen concentration - as performed by two oral immunizations - may induce tolerance to the pathogen and thereby leave the fish more vulnerable....

Power flow control using quadrature boosters

Science.gov (United States)

Sadanandan, Sandeep N.

A power system that can be controlled within security constraints would be an advantage to power planners and real-time operators. Controlling flows can lessen reliability issues such as thermal limit violations, power stability problems, and/or voltage stability conditions. Control of flows can also mitigate market issues by reducing congestion on some lines and rerouting power to less loaded lines or onto preferable paths. In the traditional control of power flows, phase shifters are often used. More advanced methods include using Flexible AC Transmission System (FACTS) Controllers. Some examples include Thyristor Controlled Series Capacitors, Synchronous Series Static Compensators, and Unified Power Flow Controllers. Quadrature Boosters (QBs) have similar structures to phase-shifters, but allow for higher voltage magnitude during real power flow control. In comparison with other FACTS controllers QBs are not as complex and not as expensive. The present study proposes to use QBs to control power flows on a power system. With the inclusion of QBs, real power flows can be controlled to desired scheduled values. In this thesis, the linearized power flow equations used for power flow analysis were modified for the control problem. This included modifying the Jacobian matrix, the power error vector, and calculating the voltage injected by the quadrature booster for the scheduled real power flow. Two scenarios were examined using the proposed power flow control method. First, the power flow in a line in a 5-bus system was modified with a QB using the method developed in this thesis. Simulation was carried out using Matlab. Second, the method was applied to a 30-bus system and then to a 118-bus system using several QBs. In all the cases, the calculated values of the QB voltages led to desired power flows in the designated line.

Leukocyte transcript alterations in West-African girls following a booster vaccination with diphtheria-tetanus-pertussis vaccine

DEFF Research Database (Denmark)

Orntoft, Nikolaj W; Thorsen, Kasper; Benn, Christine S

2013-01-01

identified a group of nine comparable West African girls, from a biobank of 356 children, who were due to receive DTP booster vaccine at age 18 months. As a pilot experiment we extracted RNA from blood samples before, and 6 weeks after, vaccination to analyze the coding transcriptome in leukocytes using......Background. Observational studies from low-income countries have shown that the vaccination against diphtheria, tetanus and pertussis (DTP) is associated with excess female mortality due to infectious diseases. Methods. To investigate possible changes in gene expression after DTP vaccination, we...... expression microarrays, and ended up with information from eight girls. The data was further analyzed using dedicated array pathway and network software. We aimed to study whether DTP vaccination introduced a systematic alteration in the immune system in girls. Results. We found very few transcripts to alter...

Percutaneous radiofrequency ablation of hepatocellular carcinoma: analysis of 80 patients treated with two consecutive sessions

International Nuclear Information System (INIS)

Rhim, Hyunchul; Kim, Young-sun; Choi, Dongil; Lim, Hyo K.; Park, KoWoon

2008-01-01

This study investigated the reasons for some patients requiring two consecutive sessions of percutaneous radiofrequency (RF) ablation of hepatocellular carcinoma (HCC). We reviewed our database of 1,179 patients (1,624 treatments) with HCCs treated by percutaneous ultrasound (US)-guided RF ablation over 6 years. We retrospectively evaluated 80 patients who required a second session after the first session. The medical records and follow-up CTs were studied. We assessed the reasons for the second session and the patient outcomes. A second session was required in 80 (4.8%) out of 1,642 treatments of percutaneous RF ablation for HCC. The reason for the second session included technical failure related to the patient or the procedure (n=26), technical failure due to residual (n=40), newly detected (n=11) or missed (n=3) tumors found at the immediate follow-up CT. All patients were retreated with a second RFA session the next day. Seventy-five (93%) of 80 patients achieved complete ablation after the second session. The remaining five patients were treated by TACE (n=1), additional RFA (as second treatment at next admission) (n=3), or were lost to follow-up (n=1). After 1 month follow-up, 72 patients (96%) showed complete ablation after the second session. The interventional oncologist should understand the technical reasons for a patient requiring a second session of RF ablation when providing treatment for HCCs and perform careful pre-procedural planning to minimize the need for multi-session procedures. (orig.)

USE OF MULTIPLE RESPONSE QUESTIONS (MRQS DURING LECTURE SESSIONS AS A TOOL TO ENHANCE LEARNING

Directory of Open Access Journals (Sweden)

Rosh

2015-12-01

Full Text Available INTRODUCTION Lecture classes are time tested solid method of teaching and have lot of advantages and few disadvantages. The main drawback is its unidirectional monotonous nature and many a time students fail to concentrate and understand especially when the sessions are long, and from the students’ point of view, many are boring too. Lecture sessions are still continued because of its various advantages. There are many methods tried to improve efficacy and effectiveness of lecture sessions including reinforcement, questions and discussions. There are many studies incorporating multiple choice questions (MCQs in lecture sessions for this purpose, with positive results. These sessions evoke creative thinking and enhance learning. For this purpose MCQs are to be prepared with care considering the areas to be covered. In order to make lecture classes more impressive, interesting and effective, we tried introducing a short multiple response session in between, along with some rewards for correct responses in terms of study materials. AIMS AND OBJECTIVES To study the impact of incorporation of MRQs during theory sessions to enhance the efficacy of teaching- learning process MATERIAL AND METHODS Study was conducted in a private medical college in Calicut. We surveyed 169 MBBS students initially with questionnaire covering various aspects of a lecture classes in general. For the next 6 months we incorporated MRQs in routine theory classes. Survey was then conducted again on the same group using same questionnaire and the results were compared. Scores were given according to performance, a maximum of 5 per question. RESULTS After 6 months the data showed substantial improvement in the understanding pattern of students. The average score regarding the usefulness increased from 3.57 to 3.91. After the intervention a substantial number agreed that the sessions have become more interesting, the score changed from 2.99 to 3.87. This also increased the

The harmonic composition of the output voltage of a rectifier unit with a PWM voltage booster converter.

OpenAIRE

ПАНЧЕНКО, В В

2015-01-01

The author investigates a rectifier unit constructed on the basis of cascade connection of the main non-controlled m-pulse rectifier and PWM voltage booster converter. The research presents the analysis of the harmonic composition of the output voltage of a rectifier unit with a PWM voltage booster converter on completely controlled keys. The dependence of the relative harmonic amplitude on the commutation corner is defined. The estimation of a rectifier unit electromagnetic compatibility wit...

New low-level rf system for the Fermilab Booster synchrotron

International Nuclear Information System (INIS)

Kerns, C.; Crisp, J.; Kerns, Q.; Miller, H.

1987-03-01

This paper describes the Booster low-level rf system that was constructed to meet these recently added requirements: (1) synthesizer controlled capture frequency at injection, (2) very low-phase noise over the machine cycle, (3) smooth phase-lock of beam to an external reference frequency and (4) ability to accelerate either a full turn or partial turn of beam

Dipole power supply for National Synchrotron Light Source Booster upgrade

International Nuclear Information System (INIS)

Olsen, R.; Dabrowski, J.; Murray, J.

1992-01-01

The booster at the NSLS is being upgraded from .75 to 2 pulses per second. To accomplish this, new power supplies for the dipole, quadrupole, and sextupole magnets have been designed and are being constructed. This paper will outline the design of the dipole power supply and control system, and will present results obtained thus far

Digital signal array processor for NSLS booster power supply upgrade

International Nuclear Information System (INIS)

Olsen, R.; Dabrowski, J.; Murray, J.

1993-01-01

The booster at the NSLS is being upgraded from 0.75 to 2 pulses per second. To accomplish this, new power supplied for the dipole, quadrupole, and sextupole have been installed. This paper will outline the design and function of the digital signal processor used as the primary control element in the power supply control system

Processing and evaluation of the AGS Booster ultra-high vaccum system

International Nuclear Information System (INIS)

Hseuh, H.C.; Mapes, M.; Schnitzenbaumer, P.; Shen, B.; Sikora, R.; Stattel, P.

1991-01-01

The AGS Booster is a synchrotron for the acceleration of both protons and heavy ions. To minimize the beam loss due to charge exchange of the partially stripped, low Β very heavy ions with the residual gas molecules, pressure of low 10 -11 Torr is required for the 200 m booster ring. To achieve this ultra high vacuum, chemical cleaning, vacuum furnace degassing and insitu bake were employed for all chambers and beam components. Using these procedures, vacuums of low 10 -11 Torr have been routinely achieved during the testing of individual half cells and beam components, and during the commissioning of the vacuum sectors. In this paper, the design and layout of chambers, flanges and bakeout hardware is briefly described. The vacuum processing of different components and the results of bakeout and evaluation are summarized. The experience gained during the construction and commissioning of this ultra-high vacuum system is also given. 3 refs., 3 figs., 1 tab

Superconducting linac booster for NSC Pelletron

International Nuclear Information System (INIS)

Roy, A.; Prakash, P.N.; Ajithkumar, B.P.; Ghosh, S.; Changrani, T.; Mehta, R.; Sarkar, A.; Muralidhar, S.; Dutt, R.N.; Kumar, M.; Shepard, K.W.; and others.

1996-01-01

The progress made in the heavy ion superconducting linac booster project for the Nuclear Science Centre Pelletron accelerator is overviewed. Prototypes of the accelerating structure have been fabricated at Argonne National Laboratory and undergone several diagnostic tests. In the first phase heavy ions up to mass 80 will be accelerated to energies above the Coulomb barrier and in the second phase the mass limit would be increased to 120. The subsystems of the project are the basic accelerating structures, the RF instrumentation and control, the cryogenic system and the beam optics. Preliminary designs for the buncher and linac cryostats have been made. Several prototypes of RF electronics and control modules have been fabricated and tested. (R.P.)

RF field control for Kaon Factory booster cavities

International Nuclear Information System (INIS)

Craig, S.T.; de Jong, M.S.

1992-08-01

A conceptual design is developed for control of the Kaon Factory booster rf accelerating fields. This design addresses control of cavity: tuning, voltage amplitude, and voltage phase angle. Time-domain simulations were developed to evaluate the proposed controllers. These simulations indicate that adequate tuning performance can be obtained with the combination of adaptive feed forward and proportional feedback control. Voltage amplitude and voltage phase can be adequately controlled using non-adaptive feed forward and proportional feedback control. (Author) (figs., tabs.)

Thermodynamic and chemical parameters of the exhaust effluents from the HARPOON booster motor

Science.gov (United States)

Stephens, J. B.; Goldford, A. I.

1978-01-01

The exhaust products from the Harpoon booster motors were analyzed using both thermodynamic analysis and finite-rate chemistry. The resulting constituents are presented together with a discussion of the techniques employed.

Hydrogen sulfide booster compressors for HWP Manuguru - oil reclamation study - BHEL experience (Paper No. 5.2)

International Nuclear Information System (INIS)

Godbole, A.; Santanam, N.; Murthy, T.S.R.

1992-01-01

BHEL undertook the development of hydrogen sulphide booster compressor with a view to indigenise this most critical equipment in a heavy water plant. Throughout the design, manufacture and shop testing of these booster compressors BHEL had close interaction with Heavy Water Board. This paper describes the problems faced during commissioning of compressors at KCR -Manuguru such as deficiencies in the sizing of LP seal oil drain, development of a process for reclamation of oil and development of alternate sealing arrangement, etc. (author). 1 tab., 4 figs

The superconducting linac booster at the ANU

International Nuclear Information System (INIS)

Weisser, D.C.

1995-02-01

This report outlines the progress of the installation of the superconducting Linac booster at the Australian National University. The Linac is based upon four modules, three of which contain three split-loop resonators. The fourth cryostat was intended to be a superbuncher and so houses only one resonator. The first stage of Linac operation will employ only three modules with 2 MV/m from each resonator. It is expected that the implementation of all nine modules, in subsequent stages, would boost beams by 18 MV/q. The project has fostered productive international collaboration between UK and Australian scientists. 1 tab., 6 figs

Sessions and Separability in Security Protocols

DEFF Research Database (Denmark)

Carbone, Marco; Guttman, Joshua

2013-01-01

Despite much work on sessions and session types in non- adversarial contexts, session-like behavior given an active adversary has not received an adequate definition and proof methods. We provide a syntactic property that guarantees that a protocol has session-respecting executions. Any uncomprom......Despite much work on sessions and session types in non- adversarial contexts, session-like behavior given an active adversary has not received an adequate definition and proof methods. We provide a syntactic property that guarantees that a protocol has session-respecting executions. Any...

Multiparty Asynchronous Session Types

DEFF Research Database (Denmark)

Honda, Kohei; Yoshida, Nobuko; Carbone, Marco

2016-01-01

. This work extends the foregoing theories of binary session types to multiparty, asynchronous sessions, which often arise in practical communication-centered applications. Presented as a typed calculus for mobile processes, the theory introduces a new notion of types in which interactions involving multiple......Communication is a central elements in software development. As a potential typed foundation for structured communication-centered programming, session types have been studied over the past decade for a wide range of process calculi and programming languages, focusing on binary (two-party) sessions...... peers are directly abstracted as a global scenario. Global types retain the friendly type syntax of binary session types while specifying dependencies and capturing complex causal chains of multiparty asynchronous interactions. A global type plays the role of a shared agreement among communication peers...

Use of a booster dose of capsular group C meningococcal glycoconjugate vaccine to demonstrate immunologic memory in children primed with one or two vaccine doses in infancy.

Science.gov (United States)

Pace, David; Khatami, Ameneh; Attard-Montalto, Simon; Voysey, Merryn; Finn, Adam; Faust, Saul N; Heath, Paul T; Borrow, Ray; Snape, Matthew D; Pollard, Andrew J

2016-12-07

Use of a polysaccharide vaccine challenge to demonstrate immunologic memory after priming with capsular group C meningococcal conjugate vaccines (MenCC) risks induction of immunologic hyporesponsiveness. For this reason, MenCC vaccines are now used as probes of immunologic memory, however, no studies have demonstrated their ability to distinguish primed from unprimed children. This study was part of a randomised controlled trial investigating the immunogenicity of a booster dose of the combined Haemophilus influenzae type b and MenC-tetanus toxoid vaccine (Hib-MenC-TT) in infants receiving reduced dose MenCC vaccine priming schedules (one MenC-CRM/MenC-TT or two MenC-CRM vaccine doses) compared with an unprimed group. Antibody kinetics were studied in a subset of 269 children by measuring changes in the MenC serum bactericidal antibody, using rabbit complement, (MenC rSBA) titres and MenC specific IgG memory B-cells before and at 6 and 28days following the 12month booster vaccination. At 6days after the 12monthMenCC vaccine, the rise in MenC rSBA titres and MenC specific IgG memory B-cells of the primed groups were significantly higher than the infant MenCC naïve group. Participants primed with one MenC-TT dose had the highest increase in MenC rSBA titres compared with all other groups. The MenC rSBA titres at the 28th compared with the 6th day after boosting was significantly higher in those primed with a single MenC-TT/MenC-CRM vaccine in infancy compared with those who were not primed or who were primed with two doses of the MenC-CRM vaccine. Immunologic memory can be demonstrated by a MenCC booster vaccination but is affected by the type and number of MenCC doses used for infant priming. The MenC rSBA responses can be used to demonstrate successful immunologic priming. Copyright © 2016 Elsevier Ltd. All rights reserved.

Space Shuttle solid rocket booster

Science.gov (United States)

Hardy, G. B.

1979-01-01

Details of the design, operation, testing and recovery procedures of the reusable solid rocket boosters (SRB) are given. Using a composite PBAN propellant, they will provide the primary thrust (six million pounds maximum at 20 s after ignition) within a 3 g acceleration constraint, as well as thrust vector control for the Space Shuttle. The drogues were tested to a load of 305,000 pounds, and the main parachutes to 205,000. Insulation in the solid rocket motor (SRM) will be provided by asbestos-silica dioxide filled acrylonitrile butadiene rubber ('asbestos filled NBR') except in high erosion areas (principally in the aft dome), where a carbon-filled ethylene propylene diene monomer-neopreme rubber will be utilized. Furthermore, twenty uses for the SRM nozzle will be allowed by its ablative materials, which are principally carbon cloth and silica cloth phenolics.

CFD Assessment of Forward Booster Separation Motor Ignition Overpressure on ET XT 718 Ice/Frost Ramp

Science.gov (United States)

Tejnil, Edward; Rogers, Stuart E.

2012-01-01

Computational fluid dynamics assessment of the forward booster separation motor ignition over-pressure was performed on the space shuttle external tank X(sub T) 718 ice/frost ramp using the flow solver OVERFLOW. The main objective of this study was the investigation of the over-pressure during solid rocket booster separation and its affect on the local pressure and air-load environments. Delta pressure and plume impingement were investigated as a possible contributing factor to the cause of the debris loss on shuttle missions STS-125 and STS-127. A simplified computational model of the Space Shuttle Launch Vehicle was developed consisting of just the external tank and the solid rocket boosters with separation motor nozzles and plumes. The simplified model was validated by comparison to full fidelity computational model of the Space Shuttle without the separation motors. Quasi steady-state plume solutions were used to calibrate the thrust of the separation motors. Time-accurate simulations of the firing of the booster-separation motors were performed. Parametric studies of the time-step size and the number of sub-iterations were used to find the best converged solution. The computed solutions were compared to previous OVERFLOW steady-state runs of the separation motors with reaction control system jets and to ground test data. The results indicated that delta pressure from the overpressure was small and within design limits, and thus was unlikely to have contributed to the foam losses.

Booster: Development of a Toolbox for Triage of a Large Group of Individuals Exposed to Radioactive Material

International Nuclear Information System (INIS)

Schoepff, V.; Carrel, F.; Gmar, M.; Lemaire, H.; Carvajal, F.; Perez-Llopis, I.; Gaboriau, D.-C.; Morrison, C.-G.; Almasi, I.; Szabo, S.; Kovacs, A; Szeles, E.; Amgarou, K.; Menaa, N.; Morat, L.; Testard, I.; Ugolin, N.; Viau, M.; Becker, F.; Raskob, W.; Trybushnyi, D.; Vincze, A.

2013-06-01

The effective management of an event involving the exposure of a large number of people to radioactive material requires a mechanism for fast triage of exposed people. BOOSTER is a project founded by the European Union under the Seventh Framework Programme, addressing this requirement. It is a capability project designed to provide an integrated system which could easily be deployed and used. For this purpose, the BOOSTER consortium, relying on the expertise of seven members, researches and develops new approaches to allow an effective and fast management of most kind of nuclear threats. BOOSTER System was designed to help first responders mitigating the crisis by providing the necessary information to quickly assess the radiological situation, to support triage staff in performing an efficient and fast categorization of the potentially affected victims, and to give medical staff crucial information for further treatment at medium or long term post-accident. (authors)

Community awareness and predictors of uptake of pertussis booster vaccine in South Australian adults.

Science.gov (United States)

Clarke, Michelle; Thomas, Natalie; Giles, Lynne; Marshall, Helen

2015-12-16

Pertussis is a highly virulent vaccine preventable disease that remains a global challenge. This study aimed to assess community knowledge of pertussis infection as well as awareness and uptake of adult pertussis booster vaccine. A cross-sectional survey was conducted of randomly selected households in South Australia by Computer Assisted Telephone Interviews in 2011. Survey data were weighted to the age, gender and geographical area profile of the population. From 3124 randomly sampled contactable households, 1967 interviews were conducted (participation rate 63%) with individuals aged 18-93 years, including 608 parents of children aged pertussis (whooping cough) and 18% reported that a household member had previously contracted whooping cough infection. Most respondents considered whooping cough to be highly contagious (73%) and severe for infants (89%). Over half (51%) of those surveyed were aware that family members commonly transmit pertussis to infants. Despite high knowledge, pertussis vaccine uptake was low, with only 10% of respondents reporting pertussis vaccination in the previous five years. Whilst 61% of respondents were aware of the availability of an adult pertussis booster vaccine, only 8% (n=154) reported their Family Physician had discussed it with them. If provided free, 77% agreed that they would be more likely to accept a booster pertussis vaccination. Independent predictors of recent pertussis vaccination included higher education, larger household size, perception of greater disease severity for infants and discussion with a Family Physician about pertussis vaccination. Whilst knowledge regarding transmission and severity of Bordetella pertussis was high, uptake of pertussis vaccination for adults is remarkably low amongst the South Australian community. Improved awareness regarding the availability of a booster pertussis vaccine through Family Physicians and/or provision of funded pertussis vaccination for adults has the potential to improve

Yellow Fever Vaccine Booster Doses: Recommendations of the Advisory Committee on Immunization Practices, 2015.

Science.gov (United States)

Staples, J Erin; Bocchini, Joseph A; Rubin, Lorry; Fischer, Marc

2015-06-19

On February 26, 2015, the Advisory Committee on Immunization Practices (ACIP) voted that a single primary dose of yellow fever vaccine provides long-lasting protection and is adequate for most travelers. ACIP also approved recommendations for at-risk laboratory personnel and certain travelers to receive additional doses of yellow fever vaccine (Box). The ACIP Japanese Encephalitis and Yellow Fever Vaccines Workgroup evaluated published and unpublished data on yellow fever vaccine immunogenicity and safety. The evidence for benefits and risks associated with yellow fever vaccine booster doses was evaluated using the Grading of Recommendations, Assessment, Development, and Evaluation (GRADE) framework. This report summarizes the evidence considered by ACIP and provides the updated recommendations for yellow fever vaccine booster doses.

A 6-month follow-up of imaginal desensitization plus motivational interviewing in the treatment of pathological gambling.

Science.gov (United States)

Grant, Jon E; Donahue, Christopher B; Odlaug, Brian L; Kim, Suck Won

2011-02-01

Pathological gambling (PG), a disabling disorder experienced by approximately 1% of adults, has few empirically validated treatments. A recent study demonstrated that 6 sessions of imaginal desensitization plus motivational interviewing (IDMI) was effective in achieving abstinence for a majority of individuals with PG. This study sought to examine whether those benefits were maintained 6 months post-treatment. Sixty-eight individuals who met DSM-IV criteria for PG were randomly assigned to 6 sessions of IDMI or Gamblers Anonymous (GA) referral over an 8-week period. Participants who failed to respond to GA were offered IDMI after the 8-week acute treatment period. All individuals who responded to IDMI were contacted after 6 months and assessed with measures of gambling severity and psychosocial functioning. Forty-four participants completed 6 sessions of IDMI (25 initially assigned to IDMI and 19 to GA). Thirty-five of the 44 (79.5%) responded during acute treatment, and all 35 were available for a 6-month evaluation. All gambling severity scales maintained statistically significant gains from baseline, although some measures showed significant worsening compared with post-IDMI treatment. Six sessions of IDMI resulted in statistically significant reductions in PG urges and behavior, which were largely maintained for 6 months.

Effects of Post-Session Wheel Running on Within-Session Changes in Operant Responding

Science.gov (United States)

Aoyama, Kenjiro

2007-01-01

This study tested the effects of post-session wheel running on within-session changes in operant responding. Lever-pressing by six rats was reinforced by a food pellet under a continuous reinforcement (CRF) schedule in 30-min sessions. Two different flavored food pellets were used as reinforcers. In the wheel conditions, 30-min operant-sessions…

Niobium quarter-wave cavity for the New Delhi booster linac

International Nuclear Information System (INIS)

Shepard, K.W.; Roy, A.; Potukuchi, P.N.

1997-01-01

This paper reports the completion of development of a 97 Mhz niobium coaxial quarter-wave cavity to be used in a booster linac for the New Delhi 16UD pellatron electrostatic accelerator. A prototype cavity, which incorporates a niobium-bellows tuning device, has been completed and operated at 4.2 K at accelerating gradients above 4 MV/m for extended periods of time

Niobium quarter-wave cavity for the New Delhi booster linac

Energy Technology Data Exchange (ETDEWEB)

Shepard, K.W. [Argonne National Lab., IL (United States); Roy, A.; Potukuchi, P.N. [Nuclear Science Centre, New Delhi (India)

1997-09-01

This paper reports the completion of development of a 97 Mhz niobium coaxial quarter-wave cavity to be used in a booster linac for the New Delhi 16UD pellatron electrostatic accelerator. A prototype cavity, which incorporates a niobium-bellows tuning device, has been completed and operated at 4.2 K at accelerating gradients above 4 MV/m for extended periods of time.

Baseline immunity to diphtheria and immunologic response after booster vaccination with reduced diphtheria and tetanus toxoid vaccine in Thai health care workers.

Science.gov (United States)

Wiboonchutikul, Surasak; Manosuthi, Weerawat; Sangsajja, Chariya; Thientong, Varaporn; Likanonsakul, Sirirat; Srisopha, Somkid; Termvises, Patamavadee; Rujitip, Jitlada; Loiusirirotchanakul, Suda; Puthavathana, Pilaipan

2014-07-01

A prospective study to evaluate immune status against diphtheria and immunologic response after tetanus-diphtheria (Td) booster vaccination was conducted in 250 Thai health care workers (HCWs). A protective antibody was found in 89.2% of the HCWs (95% confidence interval [CI], 83.3%-91.5%) before receipt of the Td booster vaccination, compared with 97.2% (95% CI, 95.1%-99.3%) after receipt of the first dose of booster (P diphtheria increased from 0.39 IU/mL (95% CI, 0.35-0.44 IU/mL) before the Td booster vaccination to 1.20 IU/mL (95% CI, 1.12-1.29 IU/mL) after the vaccination (P diphtheria, which still circulates in Thailand. Copyright © 2014 Association for Professionals in Infection Control and Epidemiology, Inc. Published by Mosby, Inc. All rights reserved.

Construction and early commissioning results of the AGS Booster

International Nuclear Information System (INIS)

Weng, W.T.; Ahrens, L.; Damm, R.; McNerney, A.J.

1991-01-01

The AGS Booster synchrotron has been designed to accelerate protons from 200 MeV to 1.5 GeV and heavy ions from several MeV per nucleon to several hundred MeV per nucleon for all the nuclei up to gold. The design requirements and measurements results of major accelerator components and systems are presented. The early commissioning results of the injection is also presented. 12 refs., 9 figs., 2 tabs

Design of the AGS Booster beam position monitor system

International Nuclear Information System (INIS)

Beadle, E.; Brennan, J.M.; Ciardullo, D.J.; Savino, J.; Stanziani, V.; Thomas, R.; Van Zwienen, W.; Witkover, R.L.; Schulte, E.

1989-01-01

The AGS Booster beam position monitor system must cover a wide range of beam intensity and bunch length for proton and heavy ion acceleration. The detector is designed to maintain 0.1 mm local tolerance following 300 degree C bakeout. The electronics will be located in the tunnel, communicating via fiber optic links to avoid ground loops. The design will be described and test results for prototype units presented. 5 refs., 4 figs

Update on Risk Reduction Activities for a Liquid Advanced Booster for NASA's Space Launch System

Science.gov (United States)

Crocker, Andrew M.; Doering, Kimberly B; Meadows, Robert G.; Lariviere, Brian W.; Graham, Jerry B.

2015-01-01

The stated goals of NASA's Research Announcement for the Space Launch System (SLS) Advanced Booster Engineering Demonstration and/or Risk Reduction (ABEDRR) are to reduce risks leading to an affordable Advanced Booster that meets the evolved capabilities of SLS; and enable competition by mitigating targeted Advanced Booster risks to enhance SLS affordability. Dynetics, Inc. and Aerojet Rocketdyne (AR) formed a team to offer a wide-ranging set of risk reduction activities and full-scale, system-level demonstrations that support NASA's ABEDRR goals. For NASA's SLS ABEDRR procurement, Dynetics and AR formed a team to offer a series of full-scale risk mitigation hardware demonstrations for an affordable booster approach that meets the evolved capabilities of the SLS. To establish a basis for the risk reduction activities, the Dynetics Team developed a booster design that takes advantage of the flight-proven Apollo-Saturn F-1. Using NASA's vehicle assumptions for the SLS Block 2, a two-engine, F-1-based booster design delivers 150 mT (331 klbm) payload to LEO, 20 mT (44 klbm) above NASA's requirements. This enables a low-cost, robust approach to structural design. During the ABEDRR effort, the Dynetics Team has modified proven Apollo-Saturn components and subsystems to improve affordability and reliability (e.g., reduce parts counts, touch labor, or use lower cost manufacturing processes and materials). The team has built hardware to validate production costs and completed tests to demonstrate it can meet performance requirements. State-of-the-art manufacturing and processing techniques have been applied to the heritage F-1, resulting in a low recurring cost engine while retaining the benefits of Apollo-era experience. NASA test facilities have been used to perform low-cost risk-reduction engine testing. In early 2014, NASA and the Dynetics Team agreed to move additional large liquid oxygen/kerosene engine work under Dynetics' ABEDRR contract. Also led by AR, the

The Effects of Space-Charge on the Dynamics of the Ion Booster in the Jefferson Lab EIC (JLEIC)

Energy Technology Data Exchange (ETDEWEB)

Bogacz, Alex [Thomas Jefferson National Accelerator Facility (TJNAF), Newport News, VA (United States); Nissen, Edward [Thomas Jefferson National Accelerator Facility (TJNAF), Newport News, VA (United States)

2017-05-01

Optimization of the booster synchrotron design to operate in the extreme space-charge dominated regime is proposed. This study is motivated by the ultra-high luminosity promised by the JLEIC accelerator complex, which poses several beam dynamics and lattice design challenges for its individual components. We examine the effects of space charge on the dynamics of the booster synchrotron for the proposed JLEIC electron ion collider. This booster will inject and accumulate protons and heavy ions at an energy of 280 MeV and then engage in a process of acceleration and electron cooling to bring it to its extraction energy of 8 GeV. This would then be sent into the ion collider ring part of JLEIC. In order to examine the effects of space charge on the dynamics of this process we use the software SYNERGIA.

Antibody response to booster vaccination with tetanus and diphtheria in adults exposed to perfluorinated alkylates.

Science.gov (United States)

Kielsen, Katrine; Shamim, Zaiba; Ryder, Lars P; Nielsen, Flemming; Grandjean, Philippe; Budtz-Jørgensen, Esben; Heilmann, Carsten

2016-01-01

Recent studies suggest that exposure to perfluorinated alkylate substances (PFASs) may induce immunosuppression in humans and animal models. In this exploratory study, 12 healthy adult volunteers were recruited. With each subject, serum-PFAS concentrations were measured and their antibody responses prospectively followed for 30 days after a booster vaccination with diphtheria and tetanus. The results indicated that serum-PFAS concentrations were positively correlated and positively associated with age and male sex. The specific antibody concentrations in serum were increased from Day 4 to Day 10 post-booster, after which a constant concentration was reached. Serum PFAS concentrations showed significant negative associations with the rate of increase in the antibody responses. Interestingly, this effect was particularly strong for the longer-chain PFASs. All significant associations remained significant after adjustment for sex and age. Although the study involved a small number of subjects, these findings of a PFAS-associated reduction of the early humoral immune response to booster vaccination in healthy adults supported previous findings of PFAS immunosuppression in larger cohorts. Furthermore, the results suggested that cellular mechanisms right after antigen exposure should be investigated more closely to identify possible mechanisms of immunosuppression from PFAS.

Panel Session

DEFF Research Database (Denmark)

Bertelsen, Olav Wedege

2004-01-01

In this panel session, four researchers will discuss the role of a theoretical foundation, in particular AT, in the design of information technology based artefacts. The general discussion will take of from a specific examination of the ActAD approach.......In this panel session, four researchers will discuss the role of a theoretical foundation, in particular AT, in the design of information technology based artefacts. The general discussion will take of from a specific examination of the ActAD approach....

Boosters and barriers for direct cardiac reprogramming.

Science.gov (United States)

Talkhabi, Mahmood; Zonooz, Elmira Rezaei; Baharvand, Hossein

2017-06-01

Heart disease is currently the most significant cause of morbidity and mortality worldwide, which accounts for approximately 33% of all deaths. Recently, a promising and alchemy-like strategy has been developed called direct cardiac reprogramming, which directly converts somatic cells such as fibroblasts to cardiac lineage cells such as cardiomyocytes (CMs), termed induced CMs or iCMs. The first in vitro cardiac reprogramming study, mediated by cardiac transcription factors (TFs)-Gata4, Tbx5 and Mef2C-, was not enough efficient to produce an adequate number of fully reprogrammed, functional iCMs. As a result, numerous combinations of cardiac TFs exist for direct cardiac reprogramming of mouse and human fibroblasts. However, the efficiency of direct cardiac reprogramming remains low. Recently, a number of cellular and molecular mechanisms have been identified to increase the efficiency of direct cardiac reprogramming and the quality of iCMs. For example, microgrooved substrate, cardiogenic growth factors [VEGF, FGF, BMP4 and Activin A], and an appropriate stoichiometry of TFs boost the direct cardiac reprogramming. On the other hand, serum, TGFβ signaling, activators of epithelial to mesenchymal transition, and some epigenetic factors (Bmi1 and Ezh2) are barriers for direct cardiac reprogramming. Manipulating these mechanisms by the application of boosters and removing barriers can increase the efficiency of direct cardiac reprogramming and possibly make iCMs reliable for cell-based therapy or other potential applications. In this review, we summarize the latest trends in cardiac TF- or miRNA-based direct cardiac reprogramming and comprehensively discuses all molecular and cellular boosters and barriers affecting direct cardiac reprogramming. Copyright © 2017 Elsevier Inc. All rights reserved.

A primary care based healthy-eating and active living education session for weight reduction in the pre-diabetic population.

Science.gov (United States)

Weir, Daniala L; Johnson, Steven T; Mundt, Clark; Bray, Dianne; Taylor, Lorian; Eurich, Dean T; Johnson, Jeffrey A

2014-12-01

Many studies have demonstrated the effectiveness of primary prevention strategies in type 2 diabetes, however, questions remain around the feasibility of high resource, intensive interventions within a healthcare setting. We report the results of a dietitian-led pre-diabetes education session targeting healthy eating and active living as strategies for weight reduction. Participants were asked to complete a baseline questionnaire prior to completing the pre-diabetes education session and were sent follow-up questionnaires at 3 and 6 months. Differences between participants at baseline, 3 and 6 months were determined using χ(2), t-tests and ANOVA. Of the 211 participants asked to fill out baseline questionnaires, 45 participants completed questionnaires at baseline, 3 months and 6 months. Although we observed general trends towards improvements in diet, physical activity and weight related behaviours among the 45 completers, no significant changes were observed among participants between questionnaire periods. A "one-off", theory-guided group education session may be insufficient to support lifestyle modifications in the context of weight management in a pre-diabetic population. Further evaluation of the efficacy and feasibility of the PCN as a setting for lifestyle intervention is required. Copyright © 2014 Primary Care Diabetes Europe. Published by Elsevier Ltd. All rights reserved.

Investigation of Post-Flight Solid Rocket Booster Thermal Protection System

Science.gov (United States)

Nelson, Linda A.

2006-01-01

After every Shuttle mission, the Solid Rocket Boosters (SRBs) are recovered and observed for missing material. Most of the SRB is covered with a cork-based thermal protection material (MCC-l). After the most recent shuttle mission, STS-114, the forward section of the booster appeared to have been impacted during flight. The darkened fracture surfaces indicated that this might have occurred early in flight. The scope of the analysis included microscopic observations to assess the degree of heat effects and locate evidence of the impact source as well as chemical analysis of the fracture surfaces and recovered foreign material using Fourier Transform Infrared Spectroscopy and Scanning Electron Microscopy/Energy Dispersive Spectroscopy. The amount of heat effects and presence of soot products on the fracture surface indicated that the material was impacted prior to SRB re-entry into the atmosphere. Fragments of graphite fibers found on these fracture surfaces were traced to slag inside the Solid Rocket Motor (SRM) that forms during flight as the propellant is spent and is ejected throughout the descent of the SRB after separation. The direction of the impact mark matches with the likely trajectory of SRBs tumbling prior to re-entry.

Primary prevention of childhood obesity through counselling sessions at Swedish child health centres

DEFF Research Database (Denmark)

Döring, Nora; Hansson, Lena M; Andersson, Elina Scheers

2014-01-01

.9%) responded to the validated physical activity and food frequency questionnaire at baseline (i.e., before the first intervention session, or, for children in the control group, before they reached 10 months of age). The food frequency questionnaire showed acceptable relative validity when compared with an 8...

The immunological effect of revaccination with Bacille Calmette-Guérin vaccine at 19 months of age.

Science.gov (United States)

Andersen, Andreas; Roth, Adam; Jensen, Kristoffer Jarlov; Erikstrup, Christian; Lisse, Ida Marie; Whittle, Hilton; Sartono, Erliyani; Yazdanbakhsh, Maria; Aaby, Peter; Benn, Christine Stabell

2013-04-19

Bacille Calmette-Guérin (BCG) vaccination has important non-specific immune effects. In a randomized trial in Guinea-Bissau, BCG revaccination was associated with significantly increased survival in children who received diphtheria-tetanus-pertussis (DTP)-booster vaccine before enrolment and in children who did not receive micronutrient supplementation (MN). Within the trial we assessed the immunological effects of BCG revaccination. Children were randomized to BCG or nothing. Blood was sampled 6-11 weeks after randomization (early sample group) or 5-9 months later (late sample group). In vitro cytokine responses (interferon (IFN)-γ, interleukin (IL)-13, tumor-necrosis-factor (TNF)-α, and IL-10) were assessed in whole blood cultures stimulated with lipopolysaccharide (LPS), purified protein derivative (PPD) or phytohaemagglutinin (PHA). Effect-modification by sex, DTP-booster vaccination and MN was studied. Cytokines were measured in 345 infants. BCG was associated with significantly increased IFN-γ (geometric mean ratio (GMR)=4.54 (95% confidence interval: 3.13-6.58)) and IL-13 (GMR=1.43 (1.00-2.05)) PPD responses, the effect being strongest in the early sample group. Across all three conditions BCG tended to increase IL-10 (LPS, PHA, PPD: GMR=1.20, 1.12, 1.20), most pronounced in the late sample group. BCG reduced the TNF-α/IL-10 ratio in boys with DTP-booster at bleeding and increased it in those without (interaction test: p=0.03). In children without MN, BCG was associated with reduced TNF-α response in the early sample group (p=0.006), and increased IL-10 in the late sample group (p=0.03). BCG revaccination resulted in a strong IFN-γ response to PPD, which waned slightly over time. BCG also affected the pro-/anti-inflammatory balance, with reduced TNF-α and increased IL-10 responses to LPS, PHA and PPD. This effect depended on sex, DTP-booster vaccination and micronutrient supplementation, being most pronounced in children who had received DTP-booster

A brain-computer interface based attention training program for treating attention deficit hyperactivity disorder.

Directory of Open Access Journals (Sweden)

Choon Guan Lim

Full Text Available Attention deficit hyperactivity disorder (ADHD symptoms can be difficult to treat. We previously reported that a 20-session brain-computer interface (BCI attention training programme improved ADHD symptoms. Here, we investigated a new more intensive BCI-based attention training game system on 20 unmedicated ADHD children (16 males, 4 females with significant inattentive symptoms (combined and inattentive ADHD subtypes. This new system monitored attention through a head band with dry EEG sensors, which was used to drive a feed forward game. The system was calibrated for each user by measuring the EEG parameters during a Stroop task. Treatment consisted of an 8-week training comprising 24 sessions followed by 3 once-monthly booster training sessions. Following intervention, both parent-rated inattentive and hyperactive-impulsive symptoms on the ADHD Rating Scale showed significant improvement. At week 8, the mean improvement was -4.6 (5.9 and -4.7 (5.6 respectively for inattentive symptoms and hyperactive-impulsive symptoms (both p<0.01. Cohen's d effect size for inattentive symptoms was large at 0.78 at week 8 and 0.84 at week 24 (post-boosters. Further analysis showed that the change in the EEG based BCI ADHD severity measure correlated with the change ADHD Rating Scale scores. The BCI-based attention training game system is a potential new treatment for ADHD.ClinicalTrials.gov NCT01344044.

Progress on the IPNS Enriched Uranium Booster Target

International Nuclear Information System (INIS)

Knox, A.E.; Carpenter, J.M.; Bailey, J.L.

1986-09-01

We describe the Enriched Uranium Booster Target designed for use in Argonne's Intense Pulsed Neutron Source. This report contains a general description of the system, and descriptions of the thermal-hydraulic and loss-of-coolant accident analyses, of the neutronic, criticality and power density calculations, of the assessment of radiation and thermal cycling growth, and of the disk fabrication methods. We also describe the calculations of radionuclide buildup and the related hazards analysis and our calculations of the temperature and stress profiles in the disks, and briefly allude to considerations of security and safeguards

Laser-plasma booster for ion post acceleration

Directory of Open Access Journals (Sweden)

Satoh D.

2013-11-01

Full Text Available A remarkable ion energy increase is demonstrated for post acceleration by a laser-plasma booster. An intense short-pulse laser generates a strong current by high-energy electrons accelerated, when this intense short-pulse laser illuminates a plasma target. The strong electric current creates a strong magnetic field along the high-energy electron current in plasma. During the increase phase in the magnetic field, a longitudinal inductive electric field is induced for the forward ion acceleration by the Faraday law. Our 2.5-dimensional particle-in-cell simulations demonstrate a remarkable increase in ion energy by several tens of MeV.

Analytical and experimental analysis of YALINA-Booster and YALINA-Thermal assemblies

International Nuclear Information System (INIS)

Kiyavitskaya, H.; Bournos, V.; Mazanik, S.; Khilmanovich, A.; Martsinkevich, B.; Routkovskaya, Ch.; Edchik, I.; Fokov, Y.; Sadovich, S.; Fedorenko, A.; Gohar, Y.; Talamo, A.

2010-01-01

Full text: Accelerator Driven Systems (ADS) may play an important role in future nuclear fuel cycles to reduce the longterm radiotoxicity and volume of spent nuclear fuel. It is proposed that ADS will produce energy and incinerate radioactive waste. This technology was called Accelerator Driven Transmutation Technology (ADTT). The most important problems of this technology are monitoring of a reactivity level in on-line regime, a choice of neutron spectrum appropriate for incineration of Minor Actinides (MA) and transmutation of Long Lived Fission Products (LLFP) and etc. Before the designing and construction of an installation it is necessary to carry out R and D to validate codes, nuclear data libraries and other instrumentations. The YALINA facility is designed to study the ADS physics and to investigate the transmutation reaction rates of MA and LLFP. The main objective of the YALINA benchmark is to compare the results from different calculation methods with each other and experimental data. The benchmark is based on the current YALINA facility configuration, which provides the opportunity to verify the prediction capability of the different methods. The experimental data have been obtained in the frame of the ISTC Projects B1341 'Analytical and experimental evaluation of the possibility to create a universal volume source of neutrons in the sub-critical booster assembly with low enrichment uranium fuel driven by a neutron generator' and B1732P 'Analytical and experimental evaluating the possibility of creation of universal volume source of neutrons in the sub-critical booster assembly with low enriched uranium fuel driven by the neutron generator'. In this paper a comparison of the experimental and calculated data obtained for YALINA-Booster subcritical assembly with a fuel of different enrichment and for YALINA-Thermal with a different number of control rods (216, 245 and 280) will be done.

Run 16 Tandem gold performance in the injectors and possible improvement with AGS type 6:3:1 bunch merge in the Booster

Energy Technology Data Exchange (ETDEWEB)

Zeno, Keith [Brookhaven National Lab. (BNL), Upton, NY (United States)

2016-10-21

During Run 16 the Tandem was used as the Gold pre-injector for a brief time so that RHIC could continue running while EBIS was down for repairs. Given the time constraints, the setup was largely derived from the EBIS Au setup. The EBIS Au setup used a 4:2:1 bunch merge in the Booster and a 12:6:2 bunch merge in the AGS.1 This note will describe the Tandem Au setup and compare it to that used for EBIS Au. The bunch merge in the Booster for Tandem Au did not work well, and it seems likely that the performance would’ve been significantly better if it did. An AGS type 6:3:1 merge in the Booster is described which might improve matters.2 Somewhat speculative estimates for the AGS bunch intensity and emittance, if that merge were successful in reducing the Booster extraction emittance to EBIS Au levels, are also given for several potential setups. Using 6 Booster loads from the Tandem, the AGS bunch intensity at extraction reached about 2.5e9 ions with a longitudinal emittance (ε) of about 0.59 eV·s/n.3 Using 12 Booster loads from EBIS, the peak bunch intensity and ε was about 3.1e9 ions and 0.75 eV·s/n, respectively. A 6.4 sec supercycle was used for both at the time, but the Tandem Au supercycle (barring any potential issues with Tandem) could probably have been reduced to about 4.6 sec.

Boosting restraint norms: a community-delivered campaign to promote booster seat use.

Science.gov (United States)

Bryant-Stephens, Tyra; Garcia-Espana, J Felipe; Winston, Flaura K

2013-01-01

The objective of this study was to evaluate the effectiveness of a theoretically grounded community-delivered marketing campaign to promote belt-positioning booster seat (BPB) use among vulnerable populations when disseminated by community members. A prospective, nonrandomized community intervention trial was conducted to evaluate the "Boosting Restraint Norms" social marketing campaign delivered by community partners in Norristown, Pennsylvania (intervention community), between October 2008 and November 2008. York, Pennsylvania, served as the comparison community. In total, 800 vehicles with 822 children aged 4 to 7 years were observed for BPB use, the primary outcome of interest, at baseline (September 2008) and at 6 months after intervention (April 2009). During the study period, a 28 percent increase in the prevalence of BPB use at 6 months was observed in the intervention community with no change in the prevalence of BPB use in the comparison community. After adjustment for child age and gender, vehicle type, driver gender, and driver level, BPB use increased from 39 to 50 percent in the intervention community. The "Boosting Restraint Norms" social marketing campaign, distributed through community organizations combined with caregiver education and a one-time free distribution of BPBs, was effective in increasing BPB use. This study demonstrates the feasibility of utilizing community organizations with established audiences to spread the "No Regrets" messaging of the campaign in the community. This study also indicates that spreading evidence-based messages in this manner may effectively change behavior in populations that are often hard to reach. Future studies are needed in which this methodology is tested in additional communities and rural settings.

Progress on the Design of a Perpendicularly Biased 2nd Harmonic Cavity for the Fermilab Booster

Energy Technology Data Exchange (ETDEWEB)

Madrak, R. L. [Fermilab; Dey, J. E. [Fermilab; Duel, K. L. [Fermilab; Kuharik, J. C. [Fermilab; Pellico, W. A. [Fermilab; Reid, J. S. [Fermilab; Romanov, G. [Fermilab; Slabough, M. [Fermilab; Sun, D. [Fermilab; Tan, C. Y. [Fermilab; Terechkine, I. [Fermilab

2016-10-01

perpendicularly biased 2nd harmonic cavity is being designed and built for the Fermilab Booster. Its purpose is to flatten the bucket at injection and thus change the longitudinal beam distribution to decrease space charge effects. It can also help at extraction. The cavity frequency range is 76 – 106 MHz. The power amplifier will be built using the Y567B tetrode, which is also used for the fundamental mode cavities in the Fermilab Booster. We discuss recent progress on the cavity, the biasing solenoid design and plans for testing the tuner's garnet material

Session Types at the Mirror

Directory of Open Access Journals (Sweden)

Luca Padovani

2009-12-01

Full Text Available We (redefine session types as projections of process behaviors with respect to the communication channels they use. In this setting, we give session types a semantics based on fair testing. The outcome is a unified theory of behavioral types that shares common aspects with conversation types and that encompass features of both dyadic and multi-party session types. The point of view we provide sheds light on the nature of session types and gives us a chance to reason about them in a framework where every notion, from well-typedness to the subtyping relation between session types, is semantically -rather than syntactically- grounded.

The linac and booster RF systems for a dedicated injector for SPEAR

International Nuclear Information System (INIS)

Weaver, J.N.; Baird, S.; Baltay, M.; Borland, M.; Nuhn, H.D.; Safranek, J.; Chavis, C.; Emery, L.; Genin, R.D.; Hettel, R.; Morales, H.; Sebek, J.; Voss, J.; Wang, D.; Wiedemann, H.; Youngmann, B.; Miller, R.H.

1991-01-01

A 120 MeV, 2,856 MHz, TW linac, with a microwave gun, alpha magnet, and chopper, has been built at SSRL as a preinjector for and along with a 3 GeV booster synchrotron ring. The resulting injector will be available on demand to fill SPEAR, which is a storage ring now dedicated to synchrotron light production. The linac sections were purchased from China, the XK-5 klystrons were obtained surplus from SLAC, the modulators are a variation on those at SLAC and were built by SSRL, the alpha magnet and chopper were designed and built at SSRL and the microwave gun was designed and built in collaboration with Varian Associates. The RF system for the booster ring is similar to those at SPEAR and PEP and was built by SSRL. Some of the interesting mechanical and electrical details are discussed and the operating characteristics of the linac and ring RF system are highlighted

The linac and booster RF systems for a dedicated injector for SPEAR

International Nuclear Information System (INIS)

Weaver, J.N.; Baird, S.; Baltay, M.; Borland, M.; Nuhn, H.D.; Safranek, J.; Chavis, C.; Emery, L.; Genin, R.D.; Hettel, R.; Morales, H.; Sebek, J.; Voss, J.; Wang, H.; Wiedemann, H.; Youngmann, B.

1991-05-01

A 120 MeV, 2856 MHz, TW linac, with a microwave gun, alpha magnet, and chopper, has been built at SSRL as a preinjector for and along with a 3 GeV booster synchrotron ring. The resulting injector will be available on demand to fill SPEAR, which is a storage ring now dedicated to synchrotron light production. The linac sections were purchased from China, the XK-5 klystrons were obtained surplus from SLAC, the modulators are a variation on those at SLAC and were built by SSRL, the alpha magnet and chopper were designed and built at SSRL and the microwave gun was designed and built in collaboration with Varian Associates. The rf system for the booster ring is similar to those at SPEAR and PEP and was built by SSRL. Some of the interesting mechanical and electrical details are discussed and the operating characteristics of the linac and ring rf system are highlighted. 8 refs., 6 figs

Monte Carlo modeling and analyses of YALINA-booster subcritical assembly part 1: analytical models and main neutronics parameters

International Nuclear Information System (INIS)

Talamo, A.; Gohar, M. Y. A.; Nuclear Engineering Division

2008-01-01

This study was carried out to model and analyze the YALINA-Booster facility, of the Joint Institute for Power and Nuclear Research of Belarus, with the long term objective of advancing the utilization of accelerator driven systems for the incineration of nuclear waste. The YALINA-Booster facility is a subcritical assembly, driven by an external neutron source, which has been constructed to study the neutron physics and to develop and refine methodologies to control the operation of accelerator driven systems. The external neutron source consists of Californium-252 spontaneous fission neutrons, 2.45 MeV neutrons from Deuterium-Deuterium reactions, or 14.1 MeV neutrons from Deuterium-Tritium reactions. In the latter two cases a deuteron beam is used to generate the neutrons. This study is a part of the collaborative activity between Argonne National Laboratory (ANL) of USA and the Joint Institute for Power and Nuclear Research of Belarus. In addition, the International Atomic Energy Agency (IAEA) has a coordinated research project benchmarking and comparing the results of different numerical codes with the experimental data available from the YALINA-Booster facility and ANL has a leading role coordinating the IAEA activity. The YALINA-Booster facility has been modeled according to the benchmark specifications defined for the IAEA activity without any geometrical homogenization using the Monte Carlo codes MONK and MCNP/MCNPX/MCB. The MONK model perfectly matches the MCNP one. The computational analyses have been extended through the MCB code, which is an extension of the MCNP code with burnup capability because of its additional feature for analyzing source driven multiplying assemblies. The main neutronics parameters of the YALINA-Booster facility were calculated using these computer codes with different nuclear data libraries based on ENDF/B-VI-0, -6, JEF-2.2, and JEF-3.1

Monte Carlo modeling and analyses of YALINA-booster subcritical assembly part 1: analytical models and main neutronics parameters.

Energy Technology Data Exchange (ETDEWEB)

Talamo, A.; Gohar, M. Y. A.; Nuclear Engineering Division

2008-09-11

This study was carried out to model and analyze the YALINA-Booster facility, of the Joint Institute for Power and Nuclear Research of Belarus, with the long term objective of advancing the utilization of accelerator driven systems for the incineration of nuclear waste. The YALINA-Booster facility is a subcritical assembly, driven by an external neutron source, which has been constructed to study the neutron physics and to develop and refine methodologies to control the operation of accelerator driven systems. The external neutron source consists of Californium-252 spontaneous fission neutrons, 2.45 MeV neutrons from Deuterium-Deuterium reactions, or 14.1 MeV neutrons from Deuterium-Tritium reactions. In the latter two cases a deuteron beam is used to generate the neutrons. This study is a part of the collaborative activity between Argonne National Laboratory (ANL) of USA and the Joint Institute for Power and Nuclear Research of Belarus. In addition, the International Atomic Energy Agency (IAEA) has a coordinated research project benchmarking and comparing the results of different numerical codes with the experimental data available from the YALINA-Booster facility and ANL has a leading role coordinating the IAEA activity. The YALINA-Booster facility has been modeled according to the benchmark specifications defined for the IAEA activity without any geometrical homogenization using the Monte Carlo codes MONK and MCNP/MCNPX/MCB. The MONK model perfectly matches the MCNP one. The computational analyses have been extended through the MCB code, which is an extension of the MCNP code with burnup capability because of its additional feature for analyzing source driven multiplying assemblies. The main neutronics parameters of the YALINA-Booster facility were calculated using these computer codes with different nuclear data libraries based on ENDF/B-VI-0, -6, JEF-2.2, and JEF-3.1.

Limits on the transverse phase space density in the Fermilab Booster

International Nuclear Information System (INIS)

Ankenbrandt, C.; Holmes, S.D.

1987-09-01

Recent results on intensity and transverse density limitations in the Fermilab 8-GeV Booster are presented. The evidence suggests that the limits are set by incoherent space-charge effects at low energy. Data are interpreted in terms of the space-charge tune shift and possible means of improving performance further are discussed. 8 refs., 3 figs

SSC High Energy Booster resonance corrector and dynamic tune scanning simulation

Energy Technology Data Exchange (ETDEWEB)

Zhang, P.; Machida, S.

1993-05-01

A resonance correction system for the High Energy Booster (HEB) of the Superconducting Super Collider (SSCL) was investigated by means of dynamic multiparticle tracking. In the simulation the operating tune is scanned as a function of time so that the bunch goes through a resonance. The performance of the half integer and third integer resonance correction system is demonstrated.

Terpineol as a novel octane booster for extending the knock limit of gasoline

KAUST Repository

Vallinayagam, R.; Vedharaj, S.; Naser, Nimal; Roberts, William L.; Dibble, Robert W.; Sarathy, Mani

2016-01-01

Improving the octane number of gasoline offers the potential of improved engine combustion, as it permits spark timing advancement without engine knock. This study proposes the use of terpineol as an octane booster for gasoline in a spark ignited

Comparison of two-dose priming plus 9-month booster with a standard three-dose priming schedule for a ten-valent pneumococcal conjugate vaccine in Nepalese infants: a randomised, controlled, open-label, non-inferiority trial.

Science.gov (United States)

Hamaluba, Mainga; Kandasamy, Rama; Upreti, Shyam R; Subedi, Giri R; Shrestha, Shrijana; Bhattarai, Shiva; Gurung, Meeru; Pradhan, Rahul; Voysey, Merryn; Gurung, Santosh; Pradhan, Shachi; Thapa, Anushil K; Maharjan, Rakesh; Kiran, Usha; Kerridge, Simon A; Hinds, Jason; van der Klis, Fiona; Snape, Matthew D; Murdoch, David R; Kelly, Sarah; Kelly, Dominic F; Adhikari, Neelam; Thorson, Stephen; Pollard, Andrew J

2015-04-01

Use of pneumococcal conjugate vaccines (PCVs) in resource-poor countries has focused on early infant immunisation with little emphasis on protection in late infancy and beyond. Boosting of the immune response later in infancy might provide improved persistence of immunogenicity into early childhood, however data are scarce. The aim of this study was to investigate if a two-dose prime with booster at age 9 months compared with a three-dose prime-only PCV schedule provided non-inferior immunogenicity in early infancy and superior persistence of antibody responses in early childhood. We did an open-label, randomised, parallel group, controlled trial in healthy infants aged 40-60 days from Kathmandu, Nepal. Participants were randomly allocated (4:4:5 ratio) to receive PCV10 in addition to routine immunisations either as a two-dose prime and boost (2+1), three-dose prime (3+0), or two doses after completion of the initial study phase (0+2). We used a computer generated randomisation list with randomly varying block sizes. We followed up participants at age 2-4 years together with a group of unvaccinated controls. Sera were analysed for opsonophagocytic activity, protein D, and PCV10 serotype-specific IgG. Laboratory staff was masked to intervention group assignment. The primary outcome measure was to determine the proportion of participants in the 2+1 group at age 10 months with specific IgG for serotypes 1, 5, and 14 of at least 0·2 μg/mL in the per-protocol population. The secondary outcomes were non-inferiority (within 10% levels) at age 18 weeks for the proportion of participants in the 2+1 group compared with the 3+0 group with serotypes 1, 5, and 14 specific IgG of at least 0·2 μg/mL; the proportion of participants with PCV10 serotype-specific IgG of at least 0·2 μg/mL and opsonophagocytic activity reciprocal titre of at least 8 at ages 18 weeks and 10 months; and nasopharyngeal pneumococcal serotype-specific carriage rates at age 9 months in each study

The safety and reactogenicity of a reduced-antigen-content diphtheria-tetanus-acellular pertussis (dTpa) booster vaccine in healthy Vietnamese children.

Science.gov (United States)

Anh, Dang Duc; Jayadeva, Girish; Kuriyakose, Sherine; Han, Htay Htay

2016-08-17

Despite effective infant immunization against pertussis, the disease continues to circulate due to waning immunity. Booster vaccinations against pertussis beyond infancy are widely recommended. In Vietnam, however, no recommendations for pertussis boosters beyond the second year of life exist. This open-label, single-centre study was designed to assess the safety of a single booster dose of reduced-antigen-content-diphtheria-tetanus-acellular-pertussis vaccine (dTpa) in 300 healthy Vietnamese children (mean age 7.9years), who had completed primary vaccination against diphtheria, tetanus and pertussis. Solicited symptoms were recorded for 4days and unsolicited and serious adverse events (SAEs) for 31days post-vaccination. Pain and fatigue were the most common solicited local and general symptoms in 35.0% and 14.0% of children, respectively. Grade 3 swelling occurred in 3 children; no large injection site reactions or SAEs were reported. The dTpa booster vaccine was well tolerated and this study supports its administration in school age Vietnamese children. Copyright © 2016 GSK group of companies. Published by Elsevier Ltd.. All rights reserved.

Summary: Hadron dynamics sessions

International Nuclear Information System (INIS)

Carroll, A.S.; Londergan, J.T.

1993-01-01

Four sessions on Hadron Dynamics were organized at this Workshop. The first topic, QCD Exclusive Reactions and Color Transparency, featured talks by Ralston, Heppelman and Strikman; the second, QCD and Inclusive Reactions had talks by Garvey, Speth and Kisslinger. The third dynamics session, Medium Modification of Elementary Interactions had contributions from Kopeliovich, Alves and Gyulassy; the fourth session Pre-QCD Dynamics and Scattering, had talks by Harris, Myhrer and Brown. An additional joint Spectroscopy/Dynamics session featured talks by Zumbro, Johnson and McClelland. These contributions are reviewed briefly in this summary. Two additional joint sessions between Dynamics and η physics are reviewed by the organizers of the Eta sessions. In such a brief review there is no way the authors can adequately summarize the details of the physics presented here. As a result, they concentrate only on brief impressionistic sketches of the physics topics discussed and their interrelations. They include no bibliography in this summary, but simply refer to the talks given in more detail in the Workshop proceedings. They focus on topics which were common to several presentations in these sessions. First, nuclear and particle descriptions of phenomena are now clearly converging, in both a qualitative and quantitative sense; they show several examples of this convergence. Second, an important issue in hadron dynamics is the extent to which elementary interactions are modified in nuclei at high energies and/or densities, and they illustrate some of these medium effects. Finally, they focus on those dynamical issues where hadron facilities can make an important, or even a unique, contribution to the knowledge of particle and nuclear physics

Rf beam control for the AGS Booster

International Nuclear Information System (INIS)

Brennan, J.M.

1994-01-01

RF beam control systems for hadron synchrotrons have evolved over the past three decades into an essentially standard design. The key difference between hadron and lepton machines is the absence of radiation damping and existence of significant frequency variation in the case of hadrons. Although the motion of the hadron in the potential well of the rf wave is inherently stable it is not strongly damped. Damping must be provided by electronic feedback through the accelerating system. This feedback is typically called the phase loop. The technology of the rf beam control system for the AGS Booster synchrotron is described. First, the overall philosophy of the design is explained in terms of a conventional servo system that regulates the beam horizontal position in the vacuum chamber. The concept of beam transfer functions is fundamental to the mathematics of the design process and is reviewed. The beam transfer functions required for this design are derived from first principles. An overview of the beam signal pick-ups and high level rf equipment is given. The major subsystems, the frequency program, the heterodyne system, and beam feedback loops, are described in detail. Beyond accelerating the beam, the rf system must also synchronize the bunches in the Booster to the buckets in the AGS before transfer. The technical challenge in this process is heightened by the need to accomplish synchronization while the frequency is still changing. Details of the synchronization system are given. This report is intended to serve two purposes. One is to document the hardware and performance of the systems that have been built. The other is to serve as a tutorial vehicle from which the non-expert can not only learn the details of this system but also learn the principles of beam control that have led to the particular design choices made

Rf beam control for the AGS Booster

Energy Technology Data Exchange (ETDEWEB)

Brennan, J.M.

1994-09-26

RF beam control systems for hadron synchrotrons have evolved over the past three decades into an essentially standard design. The key difference between hadron and lepton machines is the absence of radiation damping and existence of significant frequency variation in the case of hadrons. Although the motion of the hadron in the potential well of the rf wave is inherently stable it is not strongly damped. Damping must be provided by electronic feedback through the accelerating system. This feedback is typically called the phase loop. The technology of the rf beam control system for the AGS Booster synchrotron is described. First, the overall philosophy of the design is explained in terms of a conventional servo system that regulates the beam horizontal position in the vacuum chamber. The concept of beam transfer functions is fundamental to the mathematics of the design process and is reviewed. The beam transfer functions required for this design are derived from first principles. An overview of the beam signal pick-ups and high level rf equipment is given. The major subsystems, the frequency program, the heterodyne system, and beam feedback loops, are described in detail. Beyond accelerating the beam, the rf system must also synchronize the bunches in the Booster to the buckets in the AGS before transfer. The technical challenge in this process is heightened by the need to accomplish synchronization while the frequency is still changing. Details of the synchronization system are given. This report is intended to serve two purposes. One is to document the hardware and performance of the systems that have been built. The other is to serve as a tutorial vehicle from which the non-expert can not only learn the details of this system but also learn the principles of beam control that have led to the particular design choices made.

Immunogenicity and safety after booster vaccination of diphtheria, tetanus, and acellular pertussis in young adults: an open randomized controlled trial in Japan.

Science.gov (United States)

Hara, Megumi; Okada, Kenji; Yamaguchi, Yuko; Uno, Shingo; Otsuka, Yasuko; Shimanoe, Chisato; Nanri, Hinako; Horita, Mikako; Ozaki, Iwata; Nishida, Yuichiro; Tanaka, Keitaro

2013-12-01

The recent increase of pertussis in young adults in Japan is hypothesized to be due in part to waning protection from the acellular pertussis vaccine. While a booster immunization may prevent an epidemic of pertussis among these young adults, little is known about the safety and immunogenicity of such a booster with the diphtheria, tetanus, and acellular pertussis vaccine (DTaP), which is currently available in Japan. One hundred and eleven medical students with a mean age of 19.4 years were randomly divided into 2 groups of 55 and 56 subjects and received, respectively, 0.2 or 0.5 ml of DTaP. Immunogenicity was assessed by performing the immunoassay using serum, and the geometric mean concentration (GMC), GMC ratio (GMCR), seropositive rate, and booster response rate were calculated. Adverse reactions and adverse events were monitored for 7 days after vaccination. After booster vaccination in the two groups, significant increases were found in the antibodies against pertussis toxin, filamentous hemagglutinin, diphtheria toxoid, and tetanus toxoid, and the booster response rates for all subjects reached 100%. The GMCs and GMCRs against all antigens were significantly higher in the 0.5-ml group than in the 0.2-ml group. No serious adverse events were observed. Frequencies of local reactions were similar in the 2 groups, although the frequency of severe local swelling was significantly higher in the 0.5-ml group. These data support the acceptability of booster immunization using both 0.2 and 0.5 ml of DTaP for young adults for controlling pertussis. (This study was registered at UMIN-CTR under registration number UMIN000010672.).

Cold chain and virus-free chloroplast-made booster vaccine to confer immunity against different poliovirus serotypes.

Science.gov (United States)

Chan, Hui-Ting; Xiao, Yuhong; Weldon, William C; Oberste, Steven M; Chumakov, Konstantin; Daniell, Henry

2016-11-01

The WHO recommends complete withdrawal of oral polio vaccine (OPV) type 2 by April 2016 globally and replacing with at least one dose of inactivated poliovirus vaccine (IPV). However, high-cost, limited supply of IPV, persistent circulating vaccine-derived polioviruses transmission and need for subsequent boosters remain unresolved. To meet this critical need, a novel strategy of a low-cost cold chain-free plant-made viral protein 1 (VP1) subunit oral booster vaccine after single IPV dose is reported. Codon optimization of the VP1 gene enhanced expression by 50-fold in chloroplasts. Oral boosting of VP1 expressed in plant cells with plant-derived adjuvants after single priming with IPV significantly increased VP1-IgG1 and VP1-IgA titres when compared to lower IgG1 or negligible IgA titres with IPV injections. IgA plays a pivotal role in polio eradication because of its transmission through contaminated water or sewer systems. Neutralizing antibody titres (~3.17-10.17 log 2 titre) and seropositivity (70-90%) against all three poliovirus Sabin serotypes were observed with two doses of IPV and plant-cell oral boosters but single dose of IPV resulted in poor neutralization. Lyophilized plant cells expressing VP1 stored at ambient temperature maintained efficacy and preserved antigen folding/assembly indefinitely, thereby eliminating cold chain currently required for all vaccines. Replacement of OPV with this booster vaccine and the next steps in clinical translation of FDA-approved antigens and adjuvants are discussed. © 2016 The Authors. Plant Biotechnology Journal published by Society for Experimental Biology and The Association of Applied Biologists and John Wiley & Sons Ltd.

Specific phobias in youth: a randomized controlled trial comparing one-session treatment to a parent-augmented one-session treatment.

Science.gov (United States)

Ollendick, Thomas H; Halldorsdottir, Thorhildur; Fraire, Maria G; Austin, Kristin E; Noguchi, Ryoichi J P; Lewis, Krystal M; Jarrett, Matthew A; Cunningham, Natoshia R; Canavera, Kristin; Allen, Kristy B; Whitmore, Maria J

2015-03-01

Examine the efficacy of a parent-augmented One-Session Treatment (A-OST) in treating specific phobias (SP) in youth by comparing this novel treatment to child-focused OST, a well-established treatment. A total of 97 youth (ages 6-15, 51.5% female, 84.5% White) who fulfilled diagnostic criteria for SP were randomized to either A-OST or OST. SPs were assessed with semistructured diagnostic interviews, clinician improvement ratings, and parent and child improvement ratings. In addition, measures of treatment satisfaction and parental self-efficacy were obtained. Blind assessments were completed pretreatment, posttreatment, and 1month and 6months following treatment. Analyses were undertaken using mixed models. In addition, gender, age, internalizing/externalizing problems, parent overprotection, and parent anxiety were examined as potential predictors and moderators of treatment outcome. Both treatment conditions produced similar outcomes with approximately 50% of youth in both treatments diagnosis free and judged to be much or very much improved at posttreatment and 1-month follow-up. At 6-month follow-up, however, the treatments diverged with OST resulting in marginally superior outcomes to A-OST, contrary to predictions. Only age of child predicted treatment outcome across the two treatments (older children did better); unexpectedly, none of the variables moderated treatment outcomes. Parent augmentation of OST produced no appreciable gains in treatment outcomes. Directions for future research are highlighted. Copyright © 2014. Published by Elsevier Ltd.

An object-oriented implementation of the TRIUMF 92 MHz booster cavity control system

International Nuclear Information System (INIS)

Wilkinson, N.A.; Ludgate, G.A.

1992-01-01

A 92 MHz auxiliary accelerating cavity has been designed for installation inside the TRIUMF cyclotron, operating up to a maximum peak voltage of 200 kV. The cavity doubles the energy gain per turn for accelerating hydrogen ions in the energy region of 400-500 MeV, and reduces by 50% the stripping loss of the ion beam. The control system for the booster comprises a PC-based processor in a VME crate, for local control, and a 68030 processor with an ethernet connection as the interface to the TRIUMF Central Control System. The requirements for the booster control system were established by an object-oriented requirements analysis. Afterward, an object-oriented architectural design step was used to produce the processor allocation of the design, which was then implemented using C, for the VME processor, and a commercial database and screen generator product, for the VAX user interface. (author)

Septa and Distributor Developments for H- Injection into the Booster from LINAC4

CERN Document Server

Borburgh, J; Fowler, T; Hourican, M; Weterings, W

2008-01-01

The construction of Linac4 requires the modification of the existing injection system of the CERN PS Booster. A new transfer line will transport 160 MeV H- ions to this machine. A system of 5 pulsed magnets (BIDIS) and 3 vertical septa (BISMV) will distribute and inject the Linac pulses into the four-vertically separated Booster rings. Subsequently the beam will be injected horizontally, using a local bump created with bumpers (BS magnets) to bring the injected H- beam together with the orbiting proton beam onto the stripper foil. To accommodate the injected H- beam, the first of the BS magnets will have to be a septum-like device, deflecting only the orbiting beam. This paper highlights the requirements and technical issues and describes the solutions to be adopted for both the BIDIS and BISMV. The results of initial prototype testing of the BIDIS magnet will also be presented.

Booster LINAC project: introduction

International Nuclear Information System (INIS)

Storm, D.W.

1984-01-01

During the past year the DOE awarded a contract to build the superconducting booster proposed in 1982. Although the majority of the funds ($8M) of the project are construction funds included in the DOE contract, part of the project is to be done with state funds ($1.03M) and part with the operating funds (3 FTE personnel as well as costs of prototyping the resonators). Therefore it is appropriate to outline the progress in this report. The overall design was changed somewhat from that described in last year's Annual Report. Instead of 12 split ring resonators optimized for beta = 0.10 and 12 for beta = 0.16, the author has chosen to use 16 quarter wave resonators optimized for beta = 0.09 and 16 for beta = 0.18. The quarter wave resonators, which have two accelerating gaps instead of the three of the split rings, have a wider transit time factor, which is favorable for accelerating a broader range of particle masses. The quarter wave resonators are to be built of lead plated copper, following the design of Ben-Zvi and Brennan

Integrable RCS as a Proposed Replacement for Fermilab Booster

Energy Technology Data Exchange (ETDEWEB)

Eldred, Jeffrey [Fermilab; Valishev, Alexander [Fermilab

2017-03-07

Integrable optics is an innovation in particle accelerator design that potentially enables a greater betatron tune spread and damps collective instabilities. An integrable rapid-cycling synchrotron (RCS) would be an effective replacement for the Fermilab Booster, as part of a plan to reach multi-MW beam power at 120 GeV for the Fermilab high-energy neutrino program. We provide an example integrable lattice with features of a modern RCS - dispersion-free drifts, low momentum compaction factor, superperiodicity, chromaticity correction, bounded beta functions, and separate-function magnets.

A tool for model based diagnostics of the AGS Booster

International Nuclear Information System (INIS)

Luccio, A.

1993-01-01

A model-based algorithmic tool was developed to search for lattice errors by a systematic analysis of orbit data in the AGS Booster synchrotron. The algorithm employs transfer matrices calculated with MAD between points in the ring. Iterative model fitting of the data allows one to find and eventually correct magnet displacements and angles or field errors. The tool, implemented on a HP-Apollo workstation system, has proved very general and of immediate physical interpretation

Antibody response to booster vaccination with tetanus and diphtheria in adults exposed to perfluorinated alkylates

DEFF Research Database (Denmark)

Kielsen, Katrine; Shamim, Zaiba; Ryder, Lars P.

2016-01-01

Recent studies suggest that exposure to perfluorinated alkylate substances (PFASs) may induce immunosuppression in humans and animal models. In this exploratory study, 12 healthy adult volunteers were recruited. With each subject, serum-PFAS concentrations were measured and their antibody responses...... prospectively followed for 30 days after a booster vaccination with diphtheria and tetanus. The results indicated that serum-PFAS concentrations were positively correlated and positively associated with age and male sex. The specific antibody concentrations in serum were increased from Day 4 to Day 10 post......-booster, after which a constant concentration was reached. Serum PFAS concentrations showed significant negative associations with the rate of increase in the antibody responses. Interestingly, this effect was particularly strong for the longer-chain PFASs. All significant associations remained significant after...

SPIRONOLACTONE IN BIOFEEDBACK SESSIONS IN THE LOOP OF PACED BREATHING AND HEART RATE VARIABILITY IN HEALTHY VOLUNTEERS

Directory of Open Access Journals (Sweden)

E. Nazarenko

2015-12-01

Full Text Available In 7 conditionally healthy volunteers, aged from 19 to 21 years (average age is 19,53 ± 1,55 years, influence of spironolactone on alterations of regulatory systems state of the organism combined with biofeedback (BFB sessions in the loop of paced breathing (PB and heart rate variability (HRV parameters was evaluated. All volunteers were conducted 2 series of everyday BFB sessions in analyzed loop for 5 days with a 3 months interval between them, 2nd series of sessions were conducted 6 hours after oral application of 25 mg spironolactone. The data was analyzed using non-parametric statistical methods. Optimization of regulatory systems state under influence of BFB sessions in the loop of PB and HRV parameters was found. Spironolactone in studied dose had no significant effect on optimization of regulatory systems state.

Automatic delamination defect detection in radiographic sequence of rocket boosters

International Nuclear Information System (INIS)

Rebuffel, V.; Pires, S.; Caplier, A.; Lamarque, P.

2003-01-01

Solid rocket motors are routinely examined in real-time X-ray radioscopic mode. The large and cylindrical boosters are rotating between a high energy source and a two dimensional detector. The purpose of this control is to detect possible defects all through the sample. In the tangential configuration, the part of the object that intersects the X-rays beam is the peripheral one, allowing to detect the delamination defect between the propellant and the external metal envelope. But the defect detectability is very poor due to the strong attenuation of the X-rays through the motors. During the rotation of the booster, the system acquires a sequence of radiographs where the defects are visible over several successive instants. We have previously developed a real-time tomo-synthesis system, processing the radiographs on line, and based on a tomo-synthesis reconstruction algorithm in order to improve the signal-to-noise ratio. This system is installed at the industrial site of Kourou, and is currently used by the operators in charge of the visual inspection of the boosters. In this paper, we present a method that processes the digital images obtained by the system in the purpose of automatically extracting the delamination defects. Due to the size and the poor contrast of the defects, a single image is not sufficient to perform this detection. A spatio-temporal aspect is required for the algorithm to be robust and efficient. In a first step, the proposed method computes the apparent local displacement between the current radiograph and a reference one. This reference image is acquired at the beginning of the rotation, with few noise, and is supposed to be defect free. The apparent displacement is due to the non-perfect rotation positioning. It may be uniform or not, depending on the deformation of the insulation liner of the metallic wall. The images are then registered and compared. On the resulting difference image we apply a smoothed threshold to obtain an

User control of the proton beam injection trajectories into the AGS Booster

International Nuclear Information System (INIS)

D'Ottavio, T.; Kponou, A.; Luccio, A.; Alessi, J.G.; Reece, R.K.; Skelly, J.

1991-01-01

The 1.5 GeV (proton) Booster Synchrotron nearing completion at the AGS will get its 200 MeV beam from the linac, via a 34.9 m long linac-to-Booster transport line, LTB. LTB branches off from the existing linac-to-AGS transport line, HEBT, approximately 18.4 m downstream from the linac. A schematic layout of LTB is shown in the bottom part of Fig. 1. The four dipoles, DH2 through DH5, which are identical and are operated in series, provide a 126 degrees bend in the line. We have employed three strategies for implementing control of the trajectory, namely: (1) a global correction (2) a local correction (3) a zeroing correction. These, as well as their implementation, will be discussed. Operating experience obtained from early commissioning runs will be given. The hardware used to implement the correction schemes are the beam position monitors, BPMxxx, orbit correctors, DHxxx and DVxxx, and multiwire profile monitors, MWxxx. The quads are QHxxx and QVxxx. 3 refs., 3 figs

Overview and analysis of the 2016 Gold Run in the Booster and AGS

Energy Technology Data Exchange (ETDEWEB)

Zeno, K. [Brookhaven National Laboratory (BNL), Upton, NY (United States). Alternating Gradient Synchrotron

2016-09-16

Run 16 differed from preceding Au runs in that during most of it a 12:6:2 merge was employed in the AGS instead of an 8:4:2 merge. This was done to provide higher bunch intensities for RHIC. Since the approach to providing higher bunch intensities is, and has been, to merge more Booster bunches of the same intensity into one final bunch, detailing the longitudinal aspects of this setup seems quite relevant. So, aside from providing an overview of the Au portion of Run 16, this note also contains a series of emittance measurements in the Booster and AGS. Comparisons of these to similar measurements in previous runs are also made in hopes of gaining a better understanding of what factors contribute to the emittance of a bunch at AGS extraction. The note also tries to provide some context in which to understand the various merge schemes and describes a potential 8 to 1 type merge.

PS BOOSTER BEAM TESTS OF THE NEW DIGITAL BEAM CONTROL SYSTEM FOR LEIR

CERN Document Server

Angoletta, Maria Elena; Bento, J; De Long, J H; Findlay, A; Matuszkiewicz, P; Pedersen, F; Salom-Sarasqueta, A; CERN. Geneva. AB Department

2005-01-01

We have been developing a scaled-down prototype of the new digital beam control and cavity servoing system for CERN’s Low Energy Ion Ring (LEIR) slated for commissioning in 2005. The system’s hardware and software, developed as part of a CERN-BNL collaboration, are based on new all-digital technology already deployed at BNL's AGS Booster. The system relies on VME modules, carrying Digital Signal Processors (DSPs) as well as Field Programmable Gate Arrays (FPGAs), and daughter cards. New concepts deployed include software implementation, through DSPs & FPGAs, of functions traditionally executed by analogue hardware, such as reference-functions and timings generation. Additionally, a user-selectable digital data acquisition functionality provides diagnostic and troubleshoot access points, a new feature which is very useful in a digital system. The scaled-down prototype implements frequency program, radial steering, phase and radial loops capabilities and it has been tested in CERN's PS Booster (PSB) dur...

Alexander Technique Lessons or Acupuncture Sessions for Persons With Chronic Neck Pain: A Randomized Trial.

Science.gov (United States)

MacPherson, Hugh; Tilbrook, Helen; Richmond, Stewart; Woodman, Julia; Ballard, Kathleen; Atkin, Karl; Bland, Martin; Eldred, Janet; Essex, Holly; Hewitt, Catherine; Hopton, Ann; Keding, Ada; Lansdown, Harriet; Parrott, Steve; Torgerson, David; Wenham, Aniela; Watt, Ian

2015-11-03

Management of chronic neck pain may benefit from additional active self-care-oriented approaches. To evaluate clinical effectiveness of Alexander Technique lessons or acupuncture versus usual care for persons with chronic, nonspecific neck pain. Three-group randomized, controlled trial. (Current Controlled Trials: ISRCTN15186354). U.K. primary care. Persons with neck pain lasting at least 3 months, a score of at least 28% on the Northwick Park Questionnaire (NPQ) for neck pain and associated disability, and no serious underlying pathology. 12 acupuncture sessions or 20 one-to-one Alexander lessons (both 600 minutes total) plus usual care versus usual care alone. NPQ score (primary outcome) at 0, 3, 6, and 12 months (primary end point) and Chronic Pain Self-Efficacy Scale score, quality of life, and adverse events (secondary outcomes). 517 patients were recruited, and the median duration of neck pain was 6 years. Mean attendance was 10 acupuncture sessions and 14 Alexander lessons. Between-group reductions in NPQ score at 12 months versus usual care were 3.92 percentage points for acupuncture (95% CI, 0.97 to 6.87 percentage points) (P = 0.009) and 3.79 percentage points for Alexander lessons (CI, 0.91 to 6.66 percentage points) (P = 0.010). The 12-month reductions in NPQ score from baseline were 32% for acupuncture and 31% for Alexander lessons. Participant self-efficacy improved for both interventions versus usual care at 6 months (P neck pain and associated disability compared with usual care at 12 months. Enhanced self-efficacy may partially explain why longer-term benefits were sustained. Arthritis Research UK.

Status of the Upgrade of the CERN PS Booster

CERN Document Server

Hanke, K; Angoletta, M; Bartmann, W; Bartolome, S; Benedetto, E; Bertone, C; Blas, A; Bonnal, P; Borburgh, J; Bozzini, D; Butterworth, A; Carli, C; Carlier, E; Cole, J; Dahlen, P; Delonca, M; Dobers, T; Findlay, A; Froeschl, R; Hansen, J; Hay, D; Jensen, S; Lacroix, J; Le Roux, P; Lopez Hernandez, L; Maglioni, C; Masi, A; Mason, G; Mathot, S; Mikulec, B; Muttoni, Y; Newborough, A; Nisbet, D; Olek, S; Paoluzzi, M; Perillo-Marcone, A; Pittet, S; Puccio, B; Raginel, V; Riffaud, B; Ruehl, I; Sarrió Martínez, A; Tan, J; Todd, B; Venturi, V; Weterings, W

2013-01-01

The CERN PS Booster (PSB) is presently undergoing an ambitious consolidation and upgrade program within the frame of the LHC Injectors Upgrade (LIU) project. This program comprises a new injection scheme for H- ions from CERN’s new Linac4, the replacement of the main RF systems and an energy upgrade of the PSB rings from 1.4 to 2 GeV which includes the replacement of the main magnet power supply as well as the upgrade of the extraction equipment. This paper describes the status and plans of this work program.

Secure Execution of Distributed Session Programs

Directory of Open Access Journals (Sweden)

Nuno Alves

2011-10-01

Full Text Available The development of the SJ Framework for session-based distributed programming is part of recent and ongoing research into integrating session types and practical, real-world programming languages. SJ programs featuring session types (protocols are statically checked by the SJ compiler to verify the key property of communication safety, meaning that parties engaged in a session only communicate messages, including higher-order communications via session delegation, that are compatible with the message types expected by the recipient. This paper presents current work on security aspects of the SJ Framework. Firstly, we discuss our implementation experience from improving the SJ Runtime platform with security measures to protect and augment communication safety at runtime. We implement a transport component for secure session execution that uses a modified TLS connection with authentication based on the Secure Remote Password (SRP protocol. The key technical point is the delicate treatment of secure session delegation to counter a previous vulnerability. We find that the modular design of the SJ Runtime, based on the notion of an Abstract Transport for session communication, supports rapid extension to utilise additional transports whilst separating this concern from the application-level session programming task. In the second part of this abstract, we formally prove the target security properties by modelling the extended SJ delegation protocols in the pi-calculus.

Study of an energy upgrade of the CERN PS Booster

CERN Document Server

Hanke, K; Angoletta, M E; Bartmann, W; Bartolome, S; Bertone, C; Blas, A; Borburgh, J; Bozzini, D; Butterworth, A; Carli, C; Dahlen, P; Dobers, T; Findlay, A; Folch, R; Gilbert, N; Hansen, J; Hermanns, T; Jensen, S; Le Roux, P; Lopez-Hernandez, L A; Mahner, E; Masi, A; Mikulec, B; Muttoni, Y; Newborough, A; Nisbet, D; Nonis, M; Olek, S; Paoluzzi, M; Pittet, S; Puccio, B; Raginel, V; Ruehl, I; Tan, J; Todd, B; Weterings, W; Widorski, W

2011-01-01

CERN’s LHC injector chain will have to deliver beams with ultimate brilliance as the LHC is heading for increased luminosity in the coming years. In order to overcome bottlenecks in the injector chain, an increase of the beam transfer energy from the CERN Proton Synchrotron Booster (PSB) to the Proton Synchrotron (PS) has been investigated as a possible upgrade scenario. This paper gives an overview of the technical solutions and summarizes the conclusions of the feasibility study.

Autonomous booster device of a safety valve

International Nuclear Information System (INIS)

Namand, H.

1983-01-01

The invention concerns an autonomous booster device of a protection safety valve of a pressure vessel. The valve comprises a hollow structure, a seat connected with a mobile flap forming one piece with a stem and a calibration spring bearing on the stem and on the valve structure to maintain the flap bearing on the seat. The stem of the flap is prolongated in a box forming one piece with the valve structure and receives an added push of a spring. The box acts as a pressure device of which the piston can exercise on the stem a push opposite to and larger than the spring one. The feeding device of the pressure box is finally described in detail [fr

Technology for low cost solid rocket boosters.

Science.gov (United States)

Ciepluch, C.

1971-01-01

A review of low cost large solid rocket motors developed at the Lewis Research Center is given. An estimate is made of the total cost reduction obtainable by incorporating this new technology package into the rocket motor design. The propellant, case material, insulation, nozzle ablatives, and thrust vector control are discussed. The effect of the new technology on motor cost is calculated for a typical expandable 260-in. booster application. Included in the cost analysis is the influence of motor performance variations due to specific impulse and weight changes. It is found for this application that motor costs may be reduced by up to 30% and that the economic attractiveness of future large solid rocket motors will be improved when the new technology is implemented.

EVENT DRIVEN AUTOMATIC STATE MODIFICATION OF BNL'S BOOSTER FOR NASA SPACE RADIATION LABORATORY SOLAR PARTICLE SIMULATOR

International Nuclear Information System (INIS)

BROWN, D.; BINELLO, S.; HARVEY, M.; MORRIS, J.; RUSEK, A.; TSOUPAS, N.

2005-01-01

The NASA Space Radiation Laboratory (NSRL) was constructed in collaboration with NASA for the purpose of performing radiation effect studies for the NASA space program. The NSRL makes use of heavy ions in the range of 0.05 to 3 GeV/n slow extracted from BNL's AGS Booster. NASA is interested in reproducing the energy spectrum from a solar flare in the space environment for a single ion species. To do this we have built and tested a set of software tools which allow the state of the Booster and the NSRL beam line to be changed automatically. In this report we will describe the system and present results of beam tests

Monitoring of the booster biocide dichlofluanid in water and marine sediment of Greek marinas

NARCIS (Netherlands)

Hamwijk, C.; Schouten, A.; Foekema, E.M.; Ravensberg, J.C.; Collombon, M.T.; Schmidt, K.; Kugler, M.

2005-01-01

Dichlofluanid (N-dichlorofluoromethylthio-N′-dimethyl-N- phenylsulphamide) is used as booster biocide in antifouling paints. The occurrence of dichlofluanid and its metabolite DMSA (N′-dimethyl-N-phenyl- sulphamide) was monitored in seawater and marine sediment from three Greek marinas. Seawater and

Main cycle controls for the AGS Booster synchrotron

International Nuclear Information System (INIS)

Culwick, B.B.; Yen, S.

1991-01-01

The AGS Booster is a separated function synchrotron with the main excitation coils of the dipoles and quadrupoles connected electrically in series. This circuit is driven by a complex modular power supply with current and voltage reference functions to obtain the desired magnetic fields as a function of time. The dipole cycle is defined by algebraic functions specifying the desired field profile as a function of time. These functions are processed through successive phases to convert to the signals needed to provide the power supply with one current and six voltage references. The user interface and algorithms to derive the control variables are described. 4 refs., 3 figs

Summary of the 70 GeV Booster Group

International Nuclear Information System (INIS)

Makdisi, Y.; Khiari, F.

1985-06-01

The energy range of the 70 GeV SSC booster makes it difficult to employ a single technique for preserving the beam polarization. Results of DEPOL calculations show that the expected resonance strengths are below the .5 x 10 -1 level, which poses no problem for resonance jumping. It was found that a single adiabatically energized Siberian snake will not significantly depolarize the beam. Thus one good solution to the mixing problem is that the snake magnets be energized during the acceleration cycle reaching maximum operating value at 20 GeV, where they take over the resonance jumping role. The possibility of adiabatically energizing two snakes was found to be feasible

FCC-ee Pre-Booster Accelerators

CERN Document Server

Ogur, S; Zimmermann, F

2017-01-01

CERN’s ambitious new project, Future Circular Collider-ee, will have four operations as Z, W, H, and tt factories covering energies from 45.6 to 175 GeV. The main challenge of Z-operation is to achieve currents as high as 1450 mA; this will depend heavily on the injector. For this reason, we conclude that we need a high bunch charge of 3.3 × 1010, for both e− and e+, and fill 91 500 of each of those bunches into the collider. To achieve the goal, we have designed an S-band (2.856 GHz) normal conducting electron linac up to 6 GeV, which we will use to create and accelerate both electrons and positrons. Positrons will be created inside the linac at 4.46 GeV, will be accelerated up to 1.54 GeV at the linac, and will then be transferred to the designed damping ring. In this paper, we present the designed linac, damping ring, and the operational requirements of the 100 km booster.

Suppression of transverse instabilities by fast feedback in the Fermilab booster

International Nuclear Information System (INIS)

Ankenbrandt, C.; Higgins, E.F. Jr.; Johnson, R.P.

1977-01-01

Systems to damp radial and vertical instabilities of individual rf bunches in the Fermilab Booster are being implemented. The positions of individual bunches are derived from stripline pickups. The position information is transmitted over a variable delay, amplified, and applied to deflectors after one almost complete revolution, 6.25 horizontal and 6.75 vertical betatron wavelengths downstream of the pickup. Motivation, system concepts, design considerations, and initial operating experience are described

Efficacy and Duration of Immunity after Yellow Fever Vaccination: Systematic Review on the Need for a Booster Every 10 Years

Science.gov (United States)

Gotuzzo, Eduardo; Yactayo, Sergio; Córdova, Erika

2013-01-01

Current regulations stipulate a yellow fever (YF) booster every 10 years. We conducted a systematic review of the protective efficacy and duration of immunity of YF vaccine in residents of disease-endemic areas and in travelers to assess the need for a booster in these two settings and in selected populations (human immunodeficiency virus–infected persons, infants, children, pregnant women, and severely malnourished persons). Thirty-six studies and 22 reports were included. We identified 12 studies of immunogenicity, 8 of duration of immunity, 8 of vaccine response in infants and children, 7 of human-immunodeficiency virus–infected persons, 2 of pregnant women, and 1 of severely malnourished children. Based on currently available data, a single dose of YF vaccine is highly immunogenic and confers sustained life-long protective immunity against YF. Therefore, a booster dose of YF vaccine is not needed. Special considerations for selected populations are detailed. PMID:24006295

Workshop: poster session

International Nuclear Information System (INIS)

Schell, W.R.; Colgan, P.A.

1990-01-01

The poster session consisted of a microcosm of projects encompassing the wide range of problems in the radioecology of natural and semi-natural ecosystems. The authors presented a brief resume of the poster at a plenary session during which highlights were pointed out. The range of studies covered microbial transfer, fungi, insects herbicides, lichens, solid speciation of cesium, soil properties, plant cover, transfer factors from soil to plants, uptake by sludge fertilizers, fertilizer remediation and compartmental models for soil-plant uptake. (author)

Added value of multiple versus single sessions of repetitive transcranial magnetic stimulation in predicting motor cortex stimulation efficacy for refractory neuropathic pain.

Science.gov (United States)

Pommier, Benjamin; Quesada, Charles; Fauchon, Camille; Nuti, Christophe; Vassal, François; Peyron, Roland

2018-05-18

OBJECTIVE Selection criteria for offering patients motor cortex stimulation (MCS) for refractory neuropathic pain are a critical topic of research. A single session of repetitive transcranial magnetic stimulation (rTMS) has been advocated for selecting MCS candidates, but it has a low negative predictive value. Here the authors investigated whether multiple rTMS sessions would more accurately predict MCS efficacy. METHODS Patients included in this longitudinal study could access MCS after at least four rTMS sessions performed 3-4 weeks apart. The positive (PPV) and negative (NPV) predictive values of the four rTMS sessions and the correlation between the analgesic effects of the two treatments were assessed. RESULTS Twelve MCS patients underwent an average of 15.9 rTMS sessions prior to surgery; nine of the patients were rTMS responders. Postoperative follow-up was 57.8 ± 15.6 months (mean ± standard deviation). Mean percentage of pain relief (%R) was 21% and 40% after the first and fourth rTMS sessions, respectively. The corresponding mean durations of pain relief were respectively 2.4 and 12.9 days. A cumulative effect of the rTMS sessions was observed on both %R and duration of pain relief (p < 0.01). The %R value obtained with MCS was 35% after 6 months and 43% at the last follow-up. Both the PPV and NPV of rTMS were 100% after the fourth rTMS session (p = 0.0045). A significant correlation was found between %R or duration of pain relief after the fourth rTMS session and %R at the last MCS follow-up (R 2 = 0.83, p = 0.0003). CONCLUSIONS Four rTMS sessions predicted MCS efficacy better than a single session in neuropathic pain patients. Taking into account the cumulative effects of rTMS, the authors found a high-level correlation between the analgesic effects of rTMS and MCS.

Mystical-type experiences occasioned by psilocybin mediate the attribution of personal meaning and spiritual significance 14 months later.

Science.gov (United States)

Griffiths, Rr; Richards, Wa; Johnson, Mw; McCann, Ud; Jesse, R

2008-08-01

Psilocybin has been used for centuries for religious purposes; however, little is known scientifically about its long-term effects. We previously reported the effects of a double-blind study evaluating the psychological effects of a high psilocybin dose. This report presents the 14-month follow-up and examines the relationship of the follow-up results to data obtained at screening and on drug session days. Participants were 36 hallucinogen-naïve adults reporting regular participation in religious/ spiritual activities. Oral psilocybin (30 mg/70 kg) was administered on one of two or three sessions, with methylphenidate (40 mg/70 kg) administered on the other session(s). During sessions, volunteers were encouraged to close their eyes and direct their attention inward. At the 14-month follow-up, 58% and 67%, respectively, of volunteers rated the psilocybin-occasioned experience as being among the five most personally meaningful and among the five most spiritually significant experiences of their lives; 64% indicated that the experience increased well-being or life satisfaction; 58% met criteria for having had a 'complete' mystical experience. Correlation and regression analyses indicated a central role of the mystical experience assessed on the session day in the high ratings of personal meaning and spiritual significance at follow-up. Of the measures of personality, affect, quality of life and spirituality assessed across the study, only a scale measuring mystical experience showed a difference from screening. When administered under supportive conditions, psilocybin occasioned experiences similar to spontaneously occurring mystical experiences that, at 14-month follow-up, were considered by volunteers to be among the most personally meaningful and spiritually significant of their lives.

Mystical-type experiences occasioned by psilocybin mediate the attribution of personal meaning and spiritual significance 14 months later

Science.gov (United States)

Griffiths, Roland R.; Richards, William A.; Johnson, Matthew W.; McCann, Una D.; Jesse, Robert

2010-01-01

Psilocybin has been used for centuries for religious purposes; however little is known scientifically about its long-term effects. We previously reported the effects of a double-blind study evaluating the psychological effects of a high psilocybin dose. This report presents the 14-month follow-up and examines the relationship of the follow-up results to data obtained at screening and on drug session days. Participants were 36 hallucinogen-naïve adults reporting regular participation in religious/spiritual activities. Oral psilocybin (30 mg/70kg) was administered on one of two or three sessions, with methylphenidate (40 mg/70kg) administered on the other session(s). During sessions, volunteers were encouraged to close their eyes and direct their attention inward. At the 14-month follow-up, 58% and 67%, respectively, of volunteers rated the psilocybin-occasioned experience as being among the five most personally meaningful and among the five most spiritually significant experiences of their lives; 64% indicated the experience increased well-being or life satisfaction; 58% met criteria for having had a “complete” mystical experience. Correlation and regression analyses indicated a central role of the mystical experience assessed on the session day in the high ratings of personal meaning and spiritual significance at follow-up. Of the measures of personality, affect, quality of life, and spirituality assessed across the study, only a scale measuring mystical experience showed a difference from screening. When administered under supportive conditions, psilocybin occasioned experiences similar to spontaneously-occurring mystical experiences that, at 14-month follow-up, were considered by volunteers to be among the most personally meaningful and spiritually significant of their lives. PMID:18593735

Intra-session and inter-session variability of nitric oxide pulmonary diffusing capacity in adults with cystic fibrosis.

Science.gov (United States)

Radtke, Thomas; Benden, Christian; Maggi-Beba, Marion; Kriemler, Susi; van der Lee, Ivo; Dressel, Holger

2017-12-01

We evaluated the intra-session and inter-session variability of the diffusing capacity of nitric oxide (DLNO), carbon monoxide (DLCO), alveolar-capillary membrane diffusing capacity for carbon monoxide (DMCO) and pulmonary capillary blood volume (Vc) in patients with cystic fibrosis (CF). Patients performed single-breath diffusing capacity measurements during all of 3 consecutive study visits. Precision of gas diffusing parameters was quantified by within-subject standard deviation (SD ws ) and coefficient of variation (CV). Intra-session and inter-session reproducibility was determined by SD ws *2.77. 15 clinically stable patients were included. The intra-session precision of gas diffusing parameters improved over the study visits. The inter-session SD ws for DLNO, DLCO, DMCO, and Vc was 4.8, 1.3, 2.4, and 4.3, respectively. Reproducibility was 13.3, 3.8, 6.7 and 12.0mLmin -1 mmHg -1 ; CV was 4.4, 4.7, 4.4 and 5.8%, respectively. The intra-session variability of DLNO, DLCO, DMCO and Vc improves with breath-hold maneuver training in test-naïve patients with CF, indicating a learning effect. Inter-session reproducibility data are lower than those previously reported in healthy subjects. Copyright © 2017 Elsevier B.V. All rights reserved.

The Public Poster Session

Science.gov (United States)

Levine-Rasky, Cynthia

2009-01-01

This note describes the use of a student poster session as an innovative approach to student learning. The local context for the assignment is provided, followed by a description of the course for which the poster was prepared, details about the assignment including its evaluation, and practical considerations for planning a poster session. The…

Software environment and configuration for the DSP controlled NSLS booster power supplies

International Nuclear Information System (INIS)

Olsen, R.; Dabrowski, J.; Murray, J.

1993-01-01

The booster at the NSLS is being upgraded from 0.75 to 2 pulses per second by means of the installation of new dipole, quadrupole, and sextupole power supplies. The control system of these power supplies employs general purpose digital signal processing modules, and therefore, software support is required. This paper outlines the development system configuration, and the software environment

Responses of platinum, vanadium and cobalt self-powered flux detectors near simulated booster rods in a ZED-2 mockup of a Bruce reactor core

International Nuclear Information System (INIS)

French, P.M.; Shields, R.B.; Kroon, J.C.

1978-02-01

The static responses of Pt, V and Co self-powered detectors have been compared with copper-foil neutron activation profiles in reference and perturbed Bruce reactor core mockups assembled in the ZED-2 test reactor at Chalk River Nuclear Laboratories. The results indicate that the normalized response of each self-powered detector is an accurate measure of the thermal-neutron flux at locations greater than one lattice pitch from either a booster rod or the core boundary. They indicate that, in the Bruce booster/detector configuration, the normalized static Pt response overestimates the neutron flux by less than 3.5% upon full booster-rod insertion. (author)

Effects of imprint training procedure at birth on the reactions of foals at age six months.

Science.gov (United States)

Williams, J L; Friend, T H; Collins, M N; Toscano, M J; Sisto-Burt, A; Nevill, C H

2003-03-01

While imprint training procedures have been promoted in popular magazines, they have received limited scientific investigation. To determine the effects of a neonatal imprint training procedure on 6-month-old foals and to determine if any one session had a greater effect than others. Foals (n = 131) were divided into the following treatments: no imprint training, imprint training at birth, 12, 24 and 48 h after birth or imprint training only at birth, 12, 24, 48, or 72 h after birth. Foals then received minimal human handling until they were tested at 6 months. During training, time to complete exposure to the stimulus was significant for only 2 of 6 stimuli. Percentage change in baseline heart rate was significant for only 2 of 10 stimuli. These 4 effects were randomly spread across treatments. Neither the number of imprint training sessions (0, 1, or 4) nor the timing of imprint training sessions (none, birth, 12, 24, 48, or 72 h after birth) influenced the foal's behaviour at 6 months of age. In this study, imprint training did not result in better behaved, less reactive foals.

Some understandings on radial motion at transition in the Fermilab Booster

International Nuclear Information System (INIS)

Yang, Xi

2007-01-01

The transition crossing is space charge dominated in the Fermilab Booster. Since the longitudinal space charge forces are defocusing below transition and focusing above transition, they generate the mismatch at transition, which causes the longitudinal emittance growth above transition. It's proved by numerical simulation that such mismatch can be partially compensated by a particular radial motion at transition, which is operationally favored by the high intensity beam. The transition crossing in Booster is space charge dominated. Usually, the nonlinear chromatic effect can cause the emittance growth during transition because particles with different energies cross transition at different times. The transition time is set by the synchronous particle; below transition, particles with positive energies relative to the synchronous particle become unstable since they are in the wrong phase, and above transition, particles with negative energies are unstable. The dependence of the transition energy upon the momentum deviation can be adjusted via different sextupole corrector settings such that the emittance growth due to the chromatic nonlinear effect can be greatly reduced. Fortunately, at the corrector setting of I sextl = -97 A and I sexts = 97 A, the dependence can be removed, see Figure 1. Space charge forces are mainly responsible for the longitudinal emittance growth at transition

Operational status of the AGS Booster Main Ring Magnet Power Supply

International Nuclear Information System (INIS)

Soukas, A.; Bannon, M.; Geller, J.; McNerney, A.J.; Sandberg, J.; Toldo, F.; Zhang, S.Y.

1992-01-01

The Booster is a multipurpose accelerator interposed between a 200 MeV linac, a pair of 15 MV Tandem Van deGraaf accelerators, and the AGS. It can operate on slow cycles of 0.3 Hertz pulse repetition frequency up to a maximum of 7.5 Hertz. The different cycles, from long front porches for long injection or accumulation periods or flattops for slow extraction, to normal fast extraction cycles, accommodate protons, heavy ions (h.i.) and polarized protons. One of the systems enabling the flexible Booster operation is the Main Ring Magnet Power Supply (MRPS) system. It consist of a series connection of six, 1000 volt, multiphase rectifiers together with by pass switches. Two of the six operate at currents up to 6 kA and the rest up to 3 kA. All bypass switches are rated for 6 kA. The system is equipped with passive, damped LCRC filters as well as an active transformer coupled correction system. The MRPS is connected directly to the Long Island 69 Kv bus via a dedicated 20 MVA transformer. The choice of a series of modules enables the very flexible cycle generation and at the same time minimizes the deleterious effects of power factor and harmonics on the ac lines

Investigation of the McDonnell-Douglas orbiter and booster shuttle models in proximity at Mach numbers 2.0 to 6.0. Volume 7: Proximity data at Mach 4 and 6, interference free and launch vehicle data

Science.gov (United States)

Trimmer, L. L.; Love, D. A.; Decker, J. P.; Blackwell, K. L.; Strike, W. T.; Rampy, J. M.

1972-01-01

Aerodynamic data obtained from a space shuttle abort stage separation wind tunnel test are presented. The .00556 scale models of the orbiter and booster configuration were tested in close proximity using dual balances during the time period of April 21 to April 27 1971. Data were obtained for both booster and orbiter over an angle of attack range from -10 to 10 deg for zero degree sideslip angle. The models were tested at several relative incidence angles and separation distances and power conditions. Plug nozzles utilizing air were used to simulate booster and orbiter plumes at various altitudes along a nominal ascent trajectory. Powered conditions were 100, 50, 25 and 0 percent of full power for the orbiter and 100, 50 and 0 percent of full power for the booster. Pitch control effectiveness data were obtained for both booster and orbiter with power on and off. In addition, launch vehicle data with and without booster power were obtained utilizing a single balance in the booster model. Data were also obtained with the booster canard off in close proximity and for the launch configuration.

Shielding for a tandem accelerator coupled to linac booster

International Nuclear Information System (INIS)

Bhattacharyya, S.; Bisht, J.S.; Venkataraman, G.

1996-01-01

Shielding calculation for the Beam-Hall-II of pelletron facility, augmented with linac booster in its phase-II at Nuclear Science Centre, New Delhi, has been done. An estimate is obtained by reduction factor method considering source radiation of monoenergetic neutrons, which is then compared with the detail computation using computer code ALICE considering total energy and angular distribution of neutrons. Another code ASFIT is used to take into account the build up of gamma dose from (n, gamma) reactions within the concrete shield incorporating new radiation weighting factors as recommended by ICRP-60. (author). 8 refs., 2 figs

Performance of the ramping power supplies for the APS booster synchrotron

International Nuclear Information System (INIS)

Carwardine, J.A.; Milton, S.V.; McGhee, D.G.

1995-01-01

The Advanced Photon Source (APS) booster ramp cycle is completed within 250ms and repeated at 2Hz. Separate phase-controlled power supplies deliver current to each of the dipole, quadrupole, and sextupole magnet families. Tracking requirements are particularly challenging because of the fast (non-resonant) ramp. In order to meet the requirements, both conventional regulation and cycle-to-cycle adaptation are used. The power supply system and its performance are described

Performance of ultra low temperature district heating systems with utility plant and booster heat pumps

DEFF Research Database (Denmark)

Ommen, Torben Schmidt; Thorsen, Jan Eric; Markussen, Wiebke Brix

2017-01-01

The optimal integration of booster heat pumps in ultra low temperature district heating (ULTDH) was investigated and compared to the performance of low temperature district heating. Two possible heat production technologies for the DH networks were analysed, namely extraction combined heat...... temperature and the heat consumption profile. For reference conditions, the optimal return of ULTDH varies between 21 °C and 27 °C. When using a central HP to supply the DH system, the resulting coefficient of system performance (COSP) was in the range of 3.9 (-) to 4.7 (-) for equipment with realistic...... component efficiencies and effectiveness, when including the relevant parameters such as DH system pressure and heat losses. By using ULTDH with booster HPs, performance improvements of 12% for the reference calculations case were found, if the system was supplied by central HPs. Opposite results were found...

IEEE 1394 CAMERA IMAGING SYSTEM FOR BROOKHAVENS BOOSTER APPLICATION FACILITY BEAM DIAGNOSTICS

International Nuclear Information System (INIS)

BROWN, K.A.; FRAK, B.; GASSNER, D.; HOFF, L.; OLSEN, R.H.; SATOGATA, T.; TEPIKIAN, S.

2002-01-01

Brookhaven's Booster Applications Facility (BAF) will deliver resonant extracted heavy ion beams from the AGS Booster to short-exposure fixed-target experiments located at the end of the BAF beam line. The facility is designed to deliver a wide range of heavy ion species over a range of intensities from 10 3 to over 10 8 ions/pulse, and over a range of energies from 0.1 to 3.0 GeV/nucleon. With these constraints we have designed instrumentation packages which can deliver the maximum amount of dynamic range at a reasonable cost. Through the use of high quality optics systems and neutral density light filters we will achieve 4 to 5 orders of magnitude in light collection. By using digital IEEE1394 camera systems we are able to eliminate the frame-grabber stage in processing and directly transfer data at maximum rates of 400 Mb/set. In this note we give a detailed description of the system design and discuss the parameters used to develop the system specifications. We will also discuss the IEEE1394 camera software interface and the high-level user interface

Pulsed neutron source very intense, Booster

International Nuclear Information System (INIS)

Abbate, J.M.

1978-09-01

A compact Accelerator-Booster (fast, pulsed and modulate reactivity research reactor) is a new and appropriate conception to use as a very intense thermal neutrons source. Its definition and feasibility have been already described in several studies showing its relative advantages in comparison with others kinds of facilities. This work, wich is part of one of those studies, contains a general analysis on the meis facility parameters and core and shielding theoretical calculations. The following results were obtained: Selection and test of a calculation system suitable to use in compact fast reactors; Development a method to perform estimations in some safety and shielding problems and obtainment of adequate theoretical predictions on the general performance. Moreover, final results for importent parameters of the feasibility study and predesign (critical mass and volume, lifetime, etc.) and others related to the use of plutonium oxide as fuel are given and then evaluations of different basic functions are showed. (author) [es

Long-term outcomes from Healthy Eating and Exercise Lifestyle Program for overweight people with heart disease and diabetes.

Science.gov (United States)

Alharbi, Muaddi; Gallagher, Robyn; Kirkness, Ann; Sibbritt, David; Tofler, Geoffrey

2016-02-01

The benefits of exercise and weight reduction for overweight or obese people with coronary heart disease and/or diabetes mellitus are well recognised. The Healthy Eating and Exercise Lifestyle Program demonstrated these outcomes at 4 months, but longer-term outcomes are not yet reported. To determine whether positive weight, body mass index, waist and exercise duration outcomes were sustained in the long term (12 months) and to identify the independent predictors of these outcomes at 4 and 12 months. Longitudinal design, combining data of all Healthy Eating and Exercise Lifestyle Program participants (intervention and wait-list control, n = 134). Participants had a body mass index between 27 and 39 kg/m(2) and had completed cardiac rehabilitation and/or diabetes education programmes. Healthy Eating and Exercise Lifestyle Program intervention included an active phase of two 1-hour group-based supervised structured exercise sessions every week for 4 months and four 90-minute group information and support sessions. The maintenance phase included one 90-minute group-based booster information session and three 15-minute goal-focused telephone follow-up calls over 8 months. Participants had statistically significant reductions from baseline in weight, body mass index and waist circumference and improvements in exercise duration and capacity at 4 and 12 months. Time, self-efficacy, depressive symptoms and male gender were independent predictors for body mass index, waist and/or exercise duration (p Healthy Eating and Exercise Lifestyle Program was an effective programme to achieve and sustain weight loss and increase exercise participation over 1 year. © The European Society of Cardiology 2014.

Linearly Refined Session Types

Directory of Open Access Journals (Sweden)

Pedro Baltazar

2012-11-01

Full Text Available Session types capture precise protocol structure in concurrent programming, but do not specify properties of the exchanged values beyond their basic type. Refinement types are a form of dependent types that can address this limitation, combining types with logical formulae that may refer to program values and can constrain types using arbitrary predicates. We present a pi calculus with assume and assert operations, typed using a session discipline that incorporates refinement formulae written in a fragment of Multiplicative Linear Logic. Our original combination of session and refinement types, together with the well established benefits of linearity, allows very fine-grained specifications of communication protocols in which refinement formulae are treated as logical resources rather than persistent truths.

Celebrating the tenth conference session

International Nuclear Information System (INIS)

1966-01-01

Full text: This number of the Bulletin appears during a month when the tenth regular session of the Agency's General Conference is being held. It is fitting that among the special arrangements made to give added significance to such an historical landmark should be an opening address by Herr Franz Jonas, Federal President of the host country, Austria. The Festsaal of the Kongresszentrum, in the Hofburg, has now been the centre for every annual session held in Austria, except the first. On that occasion, recorded in the photograph on the cover, the Konzerthaus was made available. A commemorative series of talks dealing with topics of particular interest in the international development of the peaceful uses of atomic energy, delivered by scientists of world distinction was another idea which will add much profound thought to the records of nuclear energy. Under the chairmanship of Professor L.C. Prado, with Dr. W.B. Lewis as Moderator, the subjects chosen by the participants were : The Impact of Atomic Energy in our Society - Sir John Cockcroft; Nuclear Power Systems and their Technical Potentialities - Prof. Alexandre Leipunski; The Commercial Future of Nuclear Power - Dr. William Webster; Nuclear Science in Life Sciences - Dr. A.R. Gopal-Ayengar; Fundamental Research in Atomic Energy Centres - Prof. Louis Neel. These speeches will be reproduced in full in the Agency's Atomic Energy Review. The pages of this issue of the Bulletin are intended to give indications of the stage which the Agency has now reached in some, but by no means all, of its activities in promoting the techniques of atomic energy for the benefit of mankind. (author)

The PS Booster, PS and SPS Magnets for the next 25 years

CERN Document Server

Tommasini, D

2010-01-01

This note provides information and analysis on the present status of the magnets installed in the CERN Proton Synchrotron Booster (PSB), the Proton Synchrotron (PS) and the Super Proton Synchrotron (SPS) in view of their possible operation for the next 25 years. The note does not cover the magnets installed in the transfer lines, neither it covers the fast injection/extraction magnets (septa and kickers).

Longitudinal Recovery and Reduced Costs After 120 Sessions of Locomotor Training for Motor Incomplete Spinal Cord Injury.

Science.gov (United States)

Morrison, Sarah A; Lorenz, Douglas; Eskay, Carol P; Forrest, Gail F; Basso, D Michele

2018-03-01

To determine the impact of long-term, body weight-supported locomotor training after chronic, incomplete spinal cord injury (SCI), and to estimate the health care costs related to lost recovery potential and preventable secondary complications that may have occurred because of visit limits imposed by insurers. Prospective observational cohort with longitudinal follow-up. Eight outpatient rehabilitation centers that participate in the Christopher & Dana Reeve Foundation NeuroRecovery Network (NRN). Individuals with motor incomplete chronic SCI (American Spinal Injury Association Impairment Scale C or D; N=69; 0.1-45y after SCI) who completed at least 120 NRN physical therapy sessions. Manually assisted locomotor training (LT) in a body weight-supported treadmill environment, overground standing and stepping activities, and community integration tasks. International Standards for Neurological Classification of Spinal Cord Injury motor and sensory scores, orthostatic hypotension, bowel/bladder/sexual function, Spinal Cord Injury Functional Ambulation Inventory (SCI-FAI), Berg Balance Scale, Modified Functional Reach, 10-m walk test, and 6-minute walk test. Longitudinal outcome measure collection occurred every 20 treatments and at 6- to 12-month follow-up after discharge from therapy. Significant improvement occurred for upper and lower motor strength, functional activities, psychological arousal, sensation of bowel movement, and SCI-FAI community ambulation. Extended training enabled minimal detectable changes at 60, 80, 100, and 120 sessions. After detectable change occurred, it was sustained through 120 sessions and continued 6 to 12 months after treatment. Delivering at least 120 sessions of LT improves recovery from incomplete chronic SCI. Because walking reduces rehospitalization, LT delivered beyond the average 20-session insurance limit can reduce rehospitalizations and long-term health costs. Copyright © 2018 American Congress of Rehabilitation Medicine

Osteoporosis education improves osteoporosis knowledge and dietary calcium: comparison of a 4 week and a one-session education course.

Science.gov (United States)

Laslett, Laura L; Lynch, Joan; Sullivan, Thomas R; McNeil, Julian D

2011-08-01

Education is ideal for osteoporosis because many risk factors are modifiable. However, the efficacy of shortened education courses compared to a standard 4 week course for improving osteoporosis knowledge and healthy behaviours is not known. This study aimed to assess whether education changed knowledge and healthy behaviours over 3 months of follow-up; and whether changes in these outcomes were different between participants receiving the different education courses. Adults aged ≥ 50 years presenting to Emergency with mild to moderate trauma fractures received either the Osteoporosis Prevention and Self-Management Course (OPSMC) (4 × 2.5 h) (n = 75) or a one-session course (1 × 2.5 h) (n = 71) in a non-randomised prospective study with single-blinded allocation. Participants completed questionnaires measuring osteoporosis knowledge, dietary calcium, physical activity, calcium and exercise self-efficacy, and osteoporosis medications at baseline and 3 months. Data were analysed using mixed models and GEE regression models. Osteoporosis knowledge and calcium from food (% of RDI) increased from baseline to 3 months in both groups (P osteoporosis medications increased between baseline and 3 months in the OPSMC group while decreasing in the one-session group (P = 0.039). There were no differences between the groups or over time in physical activity, calcium or exercise self-efficacy. Osteoporosis education (either the OPSMC or the one-session course) improved osteoporosis knowledge and calcium intake after 3 months. Participants attending the OPSMC maintained medication compliance. We were unable to determine other differences between the courses. This study confirms the value of osteoporosis education for improving osteoporosis knowledge. © 2011 The Authors. International Journal of Rheumatic Diseases © 2011 Asia Pacific League of Associations for Rheumatology and Blackwell Publishing Asia Pty Ltd.

Neutralization antibody response to booster/priming immunization with new equine influenza vaccine in Japan.

Science.gov (United States)

Yamanaka, Takashi; Nemoto, Manabu; Bannai, Hiroshi; Tsujimura, Koji; Matsumura, Tomio; Kokado, Hiroshi; Gildea, Sarah; Cullinane, Ann

2018-03-02

Equine influenza (EI) vaccine has been widely used. However, the causative EI virus (H3N8) undergoes continuous antigenic drift, and the vaccine strains must be periodically reviewed and if necessary, updated to maintain vaccine efficacy against circulating viruses. In 2016, the Japanese vaccine was updated by replacing the old viruses with the Florida sub-lineage Clade (Fc) 2 virus, A/equine/Yokohama/aq13/2010 (Y10). We investigated the virus neutralization (VN) antibody response to Fc2 viruses currently circulating in Europe, after booster or primary immunization with the new vaccine. These European viruses have the amino acid substitution A144V or I179V of the hemagglutinin. In horses that had previously received a primary course and bi-annual boosters with the old vaccine booster, immunization with the updated vaccine increased the VN antibody levels against the European Fc2 viruses as well as Y10. There were no significant differences in the VN titers against Y10 and the Fc2 viruses with A144V or I179V substitution in horses that had received a primary course of the updated vaccine. However, a mixed primary course where the first dose was the old vaccine and the second dose was the updated vaccine, reduced VN titers against the European viruses compared to that against Y10. In summary, the new vaccine affords horses protective level of VN titers against the Fc2 viruses carrying A144V or I179V substitution, but our results suggest that the combination of the old and new vaccines for primary immunization would not be optimum.

A randomized controlled trial to increase information, motivation, and behavioral skills in Ugandan adolescents

Science.gov (United States)

Ybarra, Michele L.; Korchmaros, Josephine D.; Prescott, Tonya L.; Birungi, Ruth

2015-01-01

Background One in twenty-five Ugandan adolescents is HIV positive. Purpose Examine the impact of an Internet-based HIV prevention program on Information-Motivation-Behavior Skills Model-related constructs. Methods Three hundred and sixty-six sexually experienced and inexperienced students 12-18+ years-old in Mbarara, Uganda were randomly assigned to: the five-lesson CyberSenga program or treatment-as-usual. Half of the intervention participants were further randomized to a booster session. Assessments were collected at three and six months post-baseline. Results Participants’ HIV-related information improved over time at a greater rate for the intervention groups compared to the control group. Motivation for condom use changed to a greater degree over time for the intervention group – especially those in the intervention+booster group - compared to the control group. Behavioral skills for condom use, and motivation and behavioral skills for abstinence were statistically similar over time for both groups. Conclusions CyberSenga improves HIV preventive information and motivation to use condoms. PMID:25633626

47 CFR 97.513 - VE session manager requirements.

Science.gov (United States)

2010-10-01

... 47 Telecommunication 5 2010-10-01 2010-10-01 false VE session manager requirements. 97.513 Section... SERVICES AMATEUR RADIO SERVICE Qualifying Examination Systems § 97.513 VE session manager requirements. (a) A VE session manager may be selected by the VE team for each examination session. The VE session...

Electronics for damping transverse instabilities for the Fermilab booster synchrotron

International Nuclear Information System (INIS)

Higgins, E.F. Jr.

1977-01-01

Transverse instabilities are controlled by an active beam damper which corrects the orbit of individual proton bunches in the Fermilab booster synchrotron. The corrective signals, which are in reality processed versions of the beam pick-up data, are applied to the beam via power amplifier/deflector electrodes approximately one turn after sensing the bunch position. The electronic systems of the damper are configured as a closed-loop feedback arrangement. A brief outline is given of the overall damper system configuration, and the beam position detector, coaxial cable delay system, and data receiver are described

Air Force Reusable Booster System: A Quick-look, Design Focused Modeling and Cost Analysis Study

Science.gov (United States)

Zapata, Edgar

2011-01-01

This paper presents a method and an initial analysis of the costs of a reusable booster system (RBS) as envisioned by the US Department of Defense (DoD) and numerous initiatives that form the concept of Operationally Responsive Space (ORS). This paper leverages the knowledge gained from decades of experience with the semi-reusable NASA Space Shuttle to understand how the costs of a military next generation semi-reusable space transport might behave in the real world - and how it might be made as affordable as desired. The NASA Space Shuttle had a semi-expendable booster, that being the reusable Solid Rocket MotorslBoosters (SRMlSRB) and the expendable cryogenic External Tank (ET), with a reusable cargo and crew capable orbiter. This paper will explore DoD concepts that invert this architectural arrangement, using a reusable booster plane that flies back to base soon after launch, with the in-space elements of the launch system being the expendable portions. Cost estimating in the earliest stages of any potential, large scale program has limited usefulness. As a result, the emphasis here is on developing an approach, a structure, and the basic concepts that could continue to be matured as the program gains knowledge. Where cost estimates are provided, these results by necessity carry many caveats and assumptions, and this analysis becomes more about ways in which drivers of costs for diverse scenarios can be better understood. The paper is informed throughout with a design-for-cost philosophy whereby the design and technology features of the proposed RBS (who and what, the "architecture") are taken as linked at the hip to a desire to perform a certain mission (where and when), and together these inform the cost, responsiveness, performance and sustainability (how) of the system. Concepts for developing, acquiring, producing or operating the system will be shown for their inextricable relationship to the "architecture" of the system, and how these too relate to costs

Septum magnets for booster ring

International Nuclear Information System (INIS)

Mishra, R.K.; Mhaskar, S.P.; Ramamurthi, S.S.

1991-01-01

Synchrotron radiation source facility in CAT will employ one septum magnet for the injection of 20 MeV electron beam from the microtron and another septum magnet for the extraction of 700 MeV electron beam from the booster synchrotron. The septum is a boundary that combines or separates the beam by providing the different deflecting fields on either side of this boundary. In this magnet, septum sheet must be as thin as possible to reduce the beam losses and fringing field must be very low. Two septum magnets have been designed, one has 2 mm thick septum sheet for the injection of beam and another one has 3 mm thick septum sheet for the extraction of beam. The field strength of injection and extraction septum magnets, is 0.15 T and 0.88 T respectively. The fringing field near the septum sheet is only 10 G and 30 G for the injection and extraction magnet respectively. The field simulation has been done by computer code PANDIRA. The field homogeneity within gap is ± 0.1%. The design details are discussed in this paper. (author). 4 refs., 1 tab., 1 fig

Duration of episodes of untreated Acute Malnutrition in children 6–59 months as observed during monthly growth monitoring sessions in South of Bangladesh

International Nuclear Information System (INIS)

Hoq, Mohammad; Waid, Jillian

2014-01-01

Full text: Background: Planning for management of severe and moderate acute malnutrition programs requires estimation of the caseload of children in need of care. Since incidence of acute malnutrition is not readily available, estimate of caseload is often derived from survey prevalence and the estimated duration of untreated episodes of acute malnutrition. However, information on the duration of acute malnutrition is limited. Sufficient guidance has not been given to planners on how to translate wasting prevalence rates into the probable caseload of a program based on Mid Upper Arm Circumference for admission. Objective: To report the duration of acute malnutrition in children 6 – 59 months as observed during community growth monitoring in the south of Bangladesh. Methodology: The study design was retrospective cohort using administrative data from Terre des hommes’ monthly Growth Monitoring Program in Patharghata Union of Barguna District in absence of any community management. Monitoring data were available between November 2011 and December 2012 for 3340 children and on average, 1766 children were measured each month. Of these children only 585 had observations for every time point. During analysis two models were run, one which imputed missing observations based on status before and after the missing observation and one utilizing complete records. Case definition: Based on the World Health Organization’s threshold for weight-for-height z-scores and MUAC, the duration of acute malnutrition began when children were identified with acute malnutrition The duration of acute malnutrition ended when children were not identified as suffering with acute malnutrition at any monthly visit. Episodes of acute malnutrition observed during the first and last periods of growth monitoring were excluded from the estimation of duration. Results: The prevalence of global acute malnutrition varied over the year, with a peak in June/July (29.7% & 29.0%) and a low in December

Telephone referral education, and evidence of retention and transfer after six-months

Directory of Open Access Journals (Sweden)

Marshall Stuart D

2012-06-01

Full Text Available Abstract Background Effective communication between clinicians is essential for safe, efficient healthcare. We undertook a study to determine the longer-term effectiveness of an education session employing a structured method to teach referral-making skills to medical students. Methods All final year medical students received a forty-five minute education intervention consisting: discussion of effective telephone referrals; video viewing and critique; explanation, demonstration and practice using ISBAR; provision of a memory aid for use in their clinical work. Audio recordings were taken during a subsequent standardised simulation scenario and blindly assessed using a validated scoring system. Recordings were taken immediately before (control, several hours after (intervention, and at approximately six months after the education. Retention of the acronym and self-reports of transfer to the clinical environment were measured with a questionnaire at eight months. Results Referral clarity at six months was significantly improved from pre-intervention, and referral content showed a trend towards improvement. Both measures were lower than the immediate post-education test. The ISBAR acronym was remembered by 59.4% (n = 95/160 and used by the vast majority of the respondents who had made a clinical telephone referral (n = 135/143; 94.4%. Conclusions A brief education session improved telephone communication in a simulated environment above baseline for over six months, achieved functional retention of the acronym over a seven to eight month period and resulted in self reports of transfer of the learning into practice.

Summary of Technical Sessions - Summary and Recommendations

International Nuclear Information System (INIS)

2013-01-01

Technical Session 1 - Development achievements of BEPU methods and State of the Art: The objective of this session was to present the different approaches dealing with Best Estimate codes and uncertainties evaluations. Existing methods were summarized and different papers were focused on specific methods stressing their bases, peculiarities, advantages and limitations. As a result of the session a picture of the current State of the Art was obtained. The session comprised six papers. Technical Session 2 - International comparative activities: This session had as a main objective to review the activities launched in the past and present from the NEA in connection with BEPU methods, with focus on the applicability of conclusions derived from former benchmarks like UMS, the main outcomes of the recently finished BEMUSE project, and the objectives and relevance of UAM and PREMIUM projects. The session comprised four papers. Technical Session 3 - Applications: Licensing, safety analysis support, regulatory body views and industry activities: This session focused on the application of current methods in safety analyses. Contributions from industry, technical safety organizations and regulatory bodies were provided. As a result, a view of the penetration of BEPU methods in current safety analyses was obtained, as well as an indication of the evolution in the near future. Elements such as licensing practices, assessment process, etc. were considered. The session comprised nine papers. Technical Session 4. BEPU methods extension to new fields The session addressed the extension of BEPU methods beyond their current use. By now such methods are mainly applied to classic deterministic environment but it is believed that their benefits could be extended to other fields. Seven papers were presented in the session dealing with subjects that fit in the objectives established in the workshop programme. The papers cover areas like: extension to CFD, quantification of global safety

State Machine Modeling of the Space Launch System Solid Rocket Boosters

Science.gov (United States)

Harris, Joshua A.; Patterson-Hine, Ann

2013-01-01

The Space Launch System is a Shuttle-derived heavy-lift vehicle currently in development to serve as NASA's premiere launch vehicle for space exploration. The Space Launch System is a multistage rocket with two Solid Rocket Boosters and multiple payloads, including the Multi-Purpose Crew Vehicle. Planned Space Launch System destinations include near-Earth asteroids, the Moon, Mars, and Lagrange points. The Space Launch System is a complex system with many subsystems, requiring considerable systems engineering and integration. To this end, state machine analysis offers a method to support engineering and operational e orts, identify and avert undesirable or potentially hazardous system states, and evaluate system requirements. Finite State Machines model a system as a finite number of states, with transitions between states controlled by state-based and event-based logic. State machines are a useful tool for understanding complex system behaviors and evaluating "what-if" scenarios. This work contributes to a state machine model of the Space Launch System developed at NASA Ames Research Center. The Space Launch System Solid Rocket Booster avionics and ignition subsystems are modeled using MATLAB/Stateflow software. This model is integrated into a larger model of Space Launch System avionics used for verification and validation of Space Launch System operating procedures and design requirements. This includes testing both nominal and o -nominal system states and command sequences.

Transversely-biased ferrite-tuned cavity for the SSC booster

International Nuclear Information System (INIS)

Carlini, R.D.; Friedrichs, C. Jr.; Thiessen, H.A.

1985-01-01

Ferrite tuning of rf cavities is used to provide the change in frequency necessary as the velocity of particles in synchrotrons increases. A new technique in which the ferrite bias field is applied in a direction perpendicular to the rf field offers the possibility of greatly reducing the rf power dissipation in the ferrite. A possible 60 MHz design is discussed for the SSC booster. The cavity design is based on a simple coaxial quarter-wave resonator. A brief discussion is given fo the theory of perpendicular biasing. The measured electric Q's of five different microwave-type ferrite samples are reported and compared with the manufacturer's specifications. 9 fig

FY2014 Parameters for Helions and Gold Ions in Booster, AGS, and RHIC

Energy Technology Data Exchange (ETDEWEB)

Gardner, C. J. [Brookhaven National Lab. (BNL), Upton, NY (United States). Collider-Accelerator Dept.

2014-08-15

The nominal parameters for helions (helion is the bound state of two protons and one neutron, the nucleus of a helium-3 atom) and gold ions in Booster, AGS, and RHIC are given for the FY2014 running period. The parameters are found using various formulas to derive mass, helion anomalous g-factor, kinetic parameters, RF parameters, ring parameters, etc..

Treatment of borderline personality disorder in adolescents

NARCIS (Netherlands)

Schuppert, M.; Emmelkamp, P.; Nauta, M.; Black, D.W.; Blum, N.S.

2017-01-01

The chapter describes how STEPPS has been modified for the adolescent population in The Netherlands. Emotion regulation training (ERT) provides a group therapy experience for adolescents that consists of 17 weekly sessions, one session with family members and “important others” and two booster

Off-line tests of superconducting resonators of the JAERI tandem booster

International Nuclear Information System (INIS)

Shibata, Michihiro; Ishii, Tetsuro; Takeuchi, Suehiro

1993-01-01

The JAERI tandem booster linac, which consists of 46 superconducting quarter wave resonators, is under construction. Off-line tests for resonators were performed. Accelerating field levels of 7MV/m were obtained at an rf input of 4W with most resonators. A maximum field level of 12.7MV/m was obtained. The Q-value was degraded when resonators were cooled down slowly around a temperature of 120K. We investigated this phenomenon by changing the cooling rate. (author)

Elements of the system for RF power input into linear accelerator-injector for booster

International Nuclear Information System (INIS)

Mazurov, E.V.; Mal'tsev, I.G.; Shalashov, I.M.

1981-01-01

The elements of the original system for RF power input into 30 MeV linear accelerator-injector for the IHEP proton synchrotron booster are considered. A 3 dB coaxial directional coupler (T-bridge) is describedd. The characteristics of the bridge containing elements and the parameters of ballast matched load are given [ru

Effects of a 5-month football program on perceived psychological status and body composition of overweight boys

DEFF Research Database (Denmark)

Seabra, A C; Seabra, A F; Brito, J

2014-01-01

The effects of a 5-month intervention of football instruction and practice on the perceived psychological status and body composition of overweight boys were examined. Twelve boys (8-12 years; body mass index ≥ 85th percentile) participated in a structured 5-month football program, consisting...... of four weekly 60-90 min sessions with mean heart rate > 80%HRmax [football group (FG)]. A control group (CG) included eight boys of equivalent age from an obesity clinic located in the same area as the school. Both groups participated in two sessions of 45-90-min physical education per week at school....... Indicators of perceived psychological status included body image, self-esteem, attraction to participation in physical activity, and perceived physical competence measured with standardized questionnaires. Body composition was evaluated using dual-energy X-ray absorptiometry. From baseline through 5 months...

Single-session Gamma Knife radiosurgery for optic pathway/hypothalamic gliomas.

Science.gov (United States)

El-Shehaby, Amr M N; Reda, Wael A; Abdel Karim, Khaled M; Emad Eldin, Reem M; Nabeel, Ahmed M

2016-12-01

OBJECTIVE Because of their critical and central location, it is deemed necessary to fractionate when considering irradiating optic pathway/hypothalamic gliomas. Stereotactic fractionated radiotherapy is considered safer when dealing with gliomas in this location. In this study, the safety and efficacy of single-session stereotactic radiosurgery for optic pathway/hypothalamic gliomas were reviewed. METHODS Between December 2004 and June 2014, 22 patients with optic pathway/hypothalamic gliomas were treated by single-session Gamma Knife radiosurgery. Twenty patients were available for follow-up for a minimum of 1 year after treatment. The patients were 5 to 43 years (median 16 years) of age. The tumor volume was 0.15 to 18.2 cm 3 (median 3.1 cm 3 ). The prescription dose ranged from 8 to 14 Gy (median 11.5 Gy). RESULTS The mean follow-up period was 43 months. Five tumors involved the optic nerve only, and 15 tumors involved the chiasm/hypothalamus. Two patients died during the follow-up period. The tumors shrank in 12 cases, remained stable in 6 cases, and progressed in 2 cases, thereby making the tumor control rate 90%. Vision remained stable in 12 cases, improved in 6 cases, and worsened in 2 cases in which there was tumor progression. Progression-free survival was 83% at 3 years. CONCLUSIONS The initial results indicate that single-session Gamma Knife radiosurgery is a safe and effective treatment option for optic pathway/hypothalamic gliomas.

Internal Flow Simulation of Enhanced Performance Solid Rocket Booster for the Space Transportation System

Science.gov (United States)

Ahmad, Rashid A.; McCool, Alex (Technical Monitor)

2001-01-01

An enhanced performance solid rocket booster concept for the space shuttle system has been proposed. The concept booster will have strong commonality with the existing, proven, reliable four-segment Space Shuttle Reusable Solid Rocket Motors (RSRM) with individual component design (nozzle, insulator, etc.) optimized for a five-segment configuration. Increased performance is desirable to further enhance safety/reliability and/or increase payload capability. Performance increase will be achieved by adding a fifth propellant segment to the current four-segment booster and opening the throat to accommodate the increased mass flow while maintaining current pressure levels. One development concept under consideration is the static test of a "standard" RSRM with a fifth propellant segment inserted and appropriate minimum motor modifications. Feasibility studies are being conducted to assess the potential for any significant departure in component performance/loading from the well-characterized RSRM. An area of concern is the aft motor (submerged nozzle inlet, aft dome, etc.) where the altered internal flow resulting from the performance enhancing features (25% increase in mass flow rate, higher Mach numbers, modified subsonic nozzle contour) may result in increased component erosion and char. To assess this issue and to define the minimum design changes required to successfully static test a fifth segment RSRM engineering test motor, internal flow studies have been initiated. Internal aero-thermal environments were quantified in terms of conventional convective heating and discrete phase alumina particle impact/concentration and accretion calculations via Computational Fluid Dynamics (CFD) simulation. Two sets of comparative CFD simulations of the RSRM and the five-segment (IBM) concept motor were conducted with CFD commercial code FLUENT. The first simulation involved a two-dimensional axi-symmetric model of the full motor, initial grain RSRM. The second set of analyses

Formation of a single-bunch beam in the booster synchrotron at SPring-8

CERN Document Server

Suzuki, H; Ego, H; Hara, M; Hosoda, N; Kawashima, Y; Ohashi, Y; Ohshima, T; Tani, N; Yabashi, M; Yonehara, H

2000-01-01

In order to fill a radio frequency (rf) bucket with an electron beam in the storage ring at SPring-8, an rf knockout system was installed in the booster synchrotron. With this system, the energy of the electron beam injected from the linac was increased from 1 to 8 GeV. The time width of multi-bunch beams from the linac operated at 2856 MHz rf can be selected as 1 or 40 ns. The beam injected from the linac is distributed in rf buckets of the booster synchrotron operated at 508.58 MHz rf. To fill a single rf bucket with a beam, the rf knockout system is operated at a minimum beam energy of 1 GeV. By using the rf knockout system, the electron beam is effectively kept in a single rf bucket. Then the beam is injected into a targeted rf bucket in the storage ring with a precise timing system. The beam intensity of satellite rf buckets in the storage ring was measured with a photon counting method and determined to be 10 sup - sup 6 less than that of the main rf bucket. In this paper, we describe the rf knockout sy...

The AGS Booster beam loss monitor system

International Nuclear Information System (INIS)

Beadle, E.R.; Bennett, G.W.; Witkover, R.L.

1991-01-01

A beam loss monitor system has been developed for the Brookhaven National Laboratory Booster accelerator, and is designed for use with intensities of up to 1.5 x 10 13 protons and carbon to gold ions at 50-3 x 10 9 ions per pulse. This system is a significant advance over the present AGS system by improving the sensitivity, dynamic range, and data acquisition. In addition to the large dynamic range achievable, it is adaptively shifted when high losses are detected. The system uses up to 80 argon filled ion chambers as detectors, as well as newly designed electronics for processing and digitizing detector outputs. The hardware simultaneously integrates each detector output, interfaces to the beam interrupt systems, and digitizes all 80 channels to 21 bits at 170 KHz. This paper discuses the design, construction, and operation of the system. 4 refs., 2 figs

Tha AGS Booster high frequency rf system

International Nuclear Information System (INIS)

Sanders, R.; Cameron, P.; Damn, R.

1988-01-01

A high level rf system, including a power amplifier and cavity has been designed for the AGS Booster. It covers a frequency range of 2.4 to 4.2 Mhz and will be used to accelerate high intensity proton, and low intensity polarized proton beams to 1.5 GeV and heavy ions to 0.35 GeV per nucleon. A total accelerating voltage of up to 90kV will be provided by two cavities, each having two gaps. The internally cross-coupled, pushpull cavities are driven by an adjacently located power amplifier. In order to accommodate the high beam intensity, up to 0.75 /times/ 10 13 protons per bunch, a low plate resistance power tetrode is used. The tube anode is magnetically coupled to one of the cavity's two paralleled cells. The amplifier is a grounded cathode configuration driven by a remotely located solid state amplifier

Increasing Memory Self-Efficacy and Strategy Use in Hispanic Elders.

Science.gov (United States)

McDougall, Graham J

1998-01-01

This study tested the effects of a 4-week, nine-session group intervention taught in Spanish to Hispanic older adults entitled "Quieres Mejorar Tu Memoria" (Do you wish to improve your memory?). The program was based on Bandura's self-efficacy theory and was designed to increase memory self-efficacy and strategy use. A total of 33 older adults attending a senior center (mean--age = 69 years; education = 5 years; MMSE = 25) participated in the study. A booster session and a post-test were given at 3 months to the intervention group (n=22). At posttest the intervention reported greater confidence in preventing decline in their memories, and in particular greater use of the internal strategy of elaboration (2.99 vs. 3.41), and the external strategies of list (2.55 vs. 3.38) and note (3.27 vs. 3.75).

The Neuromuscular, Biochemical, and Endocrine Responses to a Single-Session Vs. Double-Session Training Day in Elite Athletes.

Science.gov (United States)

Johnston, Michael J; Cook, Christian J; Drake, David; Costley, Lisa; Johnston, Julie P; Kilduff, Liam P

2016-11-01

Johnston, MJ, Cook, CJ, Drake, D, Costley, L, Johnston, JP, and Kilduff, LP. The neuromuscular, biochemical, and endocrine responses to a single-session vs. double-session training day in elite athletes. J Strength Cond Res 30(11): 3098-3106, 2016-The aim of this study was to compare the acute neuromuscular, biochemical, and endocrine responses of a training day consisting of a speed session only with performing a speed-and-weights training session on the same day. Fifteen men who were academy-level rugby players completed 2 protocols in a randomized order. The speed-only protocol involved performing 6 maximal effort repetitions of 50-m running sprints with 5 minutes of recovery between each sprint, whereas the speed-and-weights protocol involved the same sprinting session but was followed 2 hours later by a lower-body weights session consisting of 4 sets of 5 backsquats and Romanian deadlift at 85% one repetition maximum. Testosterone, cortisol, creatine kinase, lactate, and perceived muscle soreness were determined immediately before, immediately after, 2 hours after, and 24 hours after both the protocols. Peak power, relative peak power, jump height, and average rate of force development were determined from a countermovement jump (CMJ) at the same time points. After 24-hours, muscle soreness was significantly higher after the speed-and-weights protocol compared with the speed-only protocol (effect size η = 0.253, F = 4.750, p ≤ 0.05). There was no significant difference between any of the CMJ variables at any of the posttraining time points. Likewise, creatine kinase, testosterone, and cortisol were unaffected by the addition of a weight-training session. These data indicate that the addition of a weight-training session 2 hours after a speed session, whereas increasing the perception of fatigue the next day does not result in a difference in endocrine response or in neuromuscular capability.

Augmenting one-session treatment of children's specific phobias with attention training to positive stimuli.

Science.gov (United States)

Waters, Allison M; Farrell, Lara J; Zimmer-Gembeck, Melanie J; Milliner, Ella; Tiralongo, Evelin; Donovan, Caroline L; McConnell, Harry; Bradley, Brendan P; Mogg, Karin; Ollendick, Thomas H

2014-11-01

This study examined the efficacy of combining two promising approaches to treating children's specific phobias, namely attention training and one 3-h session of exposure therapy ('one-session treatment', OST). Attention training towards positive stimuli (ATP) and OST (ATP+OST) was expected to have more positive effects on implicit and explicit cognitive mechanisms and clinical outcome measures than an attention training control (ATC) condition plus OST (ATC+OST). Thirty-seven children (6-17 years) with a specific phobia were randomly assigned to ATP+OST or ATC+OST. In ATP+OST, children completed 160 trials of attention training responding to a probe that always followed the happy face in happy-angry face pairs. In ATC+OST, the probe appeared equally often after angry and happy faces. In the same session, children completed OST targeting their phobic situation/object. Clinical outcomes included clinician, parent and child report measures. Cognitive outcomes were assessed in terms of change in attention bias to happy and angry faces and in danger and coping expectancies. Assessments were completed before and after treatment and three-months later. Compared to ATC+OST, the ATP+OST condition produced (a) significantly greater reductions in children's danger expectancies about their feared situations/object during the OST and at three-month follow-up, and (b) significantly improved attention bias towards positive stimuli at post-treatment, which in turn, predicted a lower level of clinician-rated phobia diagnostic severity three-months after treatment. There were no significant differences between ATP+OST and ATC+OST conditions in clinician, parent, or child-rated clinical outcomes. Training children with phobias to focus on positive stimuli is effective in increasing attention towards positive stimuli and reducing danger expectancy biases. Studies with larger sample sizes and a stronger 'dose' of ATP prior to the OST may reveal promising outcomes on clinical measures

Status of the Argonne superconducting-linac heavy-ion energy booster

International Nuclear Information System (INIS)

Aron, J.; Benaroya, R.; Bollinger, L.M.; Clifft, B.E.; Henning, W.; Johnson, K.W.; Nixon, J.M.; Markovich, P.; Shepard, K.W.

1979-01-01

A superconducting linac is being constructed to provide an energy booster for heavy ions from an FN tandem. By late 1980 the linac will consist of 24 independently-phased superconducting resonators, and will provide an effective accelerating potential of more than 25 MV. While the linac is under construction, completed sections are being used to provide useful beam for nuclear physics experiments. In the most recent run with beam (June 1979), an eight resonator array provided an effective accelerating potential of 9.3 MV. Operation of a 12 resonator array is scheduled to begin in October 1979

Status of the Argonne superconducting-linac heavy-ion energy booster

Energy Technology Data Exchange (ETDEWEB)

Aron, J.; Benaroya, R.; Bollinger, L.M.; Clifft, B.E.; Henning, W.; Johnson, K.W.; Nixon, J.M.; Markovich, P.; Shepard, K.W.

1979-01-01

A superconducting linac is being constructed to provide an energy booster for heavy ions from an FN tandem. By late 1980 the linac will consist of 24 independently-phased superconducting resonators, and will provide an effective accelerating potential of more than 25 MV. While the linac is under construction, completed sections are being used to provide useful beam for nuclear physics experiments. In the most recent run with beam (June 1979), an eight resonator array provided an effective accelerating potential of 9.3 MV. Operation of a 12 resonator array is scheduled to begin in October 1979.

Sensitive screening of abused drugs in dried blood samples using ultra-high-performance liquid chromatography-ion booster-quadrupole time-of-flight mass spectrometry.

Science.gov (United States)

Chepyala, Divyabharathi; Tsai, I-Lin; Liao, Hsiao-Wei; Chen, Guan-Yuan; Chao, Hsi-Chun; Kuo, Ching-Hua

2017-03-31

An increased rate of drug abuse is a major social problem worldwide. The dried blood spot (DBS) sampling technique offers many advantages over using urine or whole blood sampling techniques. This study developed a simple and efficient ultra-high-performance liquid chromatography-ion booster-quadrupole time-of-flight mass spectrometry (UHPLC-IB-QTOF-MS) method for the analysis of abused drugs and their metabolites using DBS. Fifty-seven compounds covering the most commonly abused drugs, including amphetamines, opioids, cocaine, benzodiazepines, barbiturates, and many other new and emerging abused drugs, were selected as the target analytes of this study. An 80% acetonitrile solvent with a 5-min extraction by Geno grinder was used for sample extraction. A Poroshell column was used to provide efficient separation, and under optimal conditions, the analytical times were 15 and 5min in positive and negative ionization modes, respectively. Ionization parameters of both electrospray ionization source and ion booster (IB) source containing an extra heated zone were optimized to achieve the best ionization efficiency of the investigated abused drugs. In spite of their structural diversity, most of the abused drugs showed an enhanced mass response with the high temperature ionization from an extra heated zone of IB source. Compared to electrospray ionization, the ion booster (IB) greatly improved the detection sensitivity for 86% of the analytes by 1.5-14-fold and allowed the developed method to detect trace amounts of compounds on the DBS cards. The validation results showed that the coefficients of variation of intra-day and inter-day precision in terms of the signal intensity were lower than 19.65%. The extraction recovery of all analytes was between 67.21 and 115.14%. The limits of detection of all analytes were between 0.2 and 35.7ngmL -1 . The stability study indicated that 7% of compounds showed poor stability (below 50%) on the DBS cards after 6 months of storage at

Poster Sessions in Marketing Education: An Empirical Examination

Science.gov (United States)

Stegemann, Nicole; Sutton-Brady, Catherine

2009-01-01

Poster sessions provide a creative and stimulating alternative to traditional assessment methods in marketing. Poster sessions, as a means of assessment, have long been used in science fields. This article presents the successful implementation of poster sessions as a means of assessment in a postgraduate unit of study. Poster sessions in…

Attendance at NHS mandatory training sessions.

Science.gov (United States)

Brand, Darren

2015-02-17

To identify factors that affect NHS healthcare professionals' attendance at mandatory training sessions. A quantitative approach was used, with a questionnaire sent to 400 randomly selected participants. A total of 122 responses were received, providing a mix of qualitative and quantitative data. Quantitative data were analysed using statistical methods. Open-ended responses were reviewed using thematic analysis. Clinical staff value mandatory training sessions highly. They are aware of the requirement to keep practice up-to-date and ensure patient safety remains a priority. However, changes to the delivery format of mandatory training sessions are required to enable staff to participate more easily, as staff are often unable to attend. The delivery of mandatory training should move from classroom-based sessions into the clinical area to maximise participation. Delivery should be assisted by local 'experts' who are able to customise course content to meet local requirements and the requirements of different staff groups. Improved arrangements to provide staff cover, for those attending training, would enable more staff to attend training sessions.

Using session types as an effect system

Directory of Open Access Journals (Sweden)

Dominic Orchard

2016-02-01

Full Text Available Side effects are a core part of practical programming. However, they are often hard to reason about, particularly in a concurrent setting. We propose a foundation for reasoning about concurrent side effects using sessions. Primarily, we show that session types are expressive enough to encode an effect system for stateful processes. This is formalised via an effect-preserving encoding of a simple imperative language with an effect system into the pi-calculus with session primitives and session types (into which we encode effect specifications. This result goes towards showing a connection between the expressivity of session types and effect systems. We briefly discuss how the encoding could be extended and applied to reason about and control concurrent side effects.

Multipole Stack for the 800 MeV PS Booster

CERN Multimedia

1975-01-01

The 800 MeV PS Booster had seen first beam in its 4 superposed rings in 1972, routine operation began in 1973. In the strive for ever higher beam intensities, the need for additional multipole lenses became evident. After detailed studies, the manufacture of 8 stacks of multipoles was launched in 1974. Each stack consists of 4 superposed multipoles and each multipole has 4 concentric shells. From the innermost to the outermost shell, Type A contains octupole, skew-octupole, sextupole, skew-sextupole. Type B contains skew-octupole, skew-sextupole, vertical dipole, horizontal dipole. Completion of installation in 1976 opened the way to higher beam intensities. M. Battiaz is seen here with a multipole stack and its many electrical connections.

Managing Ethical Difficulties in Healthcare: Communicating in Inter-professional Clinical Ethics Support Sessions.

Science.gov (United States)

Grönlund, Catarina Fischer; Dahlqvist, Vera; Zingmark, Karin; Sandlund, Mikael; Söderberg, Anna

2016-12-01

Several studies show that healthcare professionals need to communicate inter-professionally in order to manage ethical difficulties. A model of clinical ethics support (CES) inspired by Habermas' theory of discourse ethics has been developed by our research group. In this version of CES sessions healthcare professionals meet inter-professionally to communicate and reflect on ethical difficulties in a cooperative manner with the aim of reaching communicative agreement or reflective consensus. In order to understand the course of action during CES, the aim of this study was to describe the communication of value conflicts during a series of inter-professional CES sessions. Ten audio- and video-recorded CES sessions were conducted over eight months and were analyzed by using the video analysis tool Transana and qualitative content analysis. The results showed that during the CES sessions the professionals as a group moved through the following five phases: a value conflict expressed as feelings of frustration, sharing disempowerment and helplessness, the revelation of the value conflict, enhancing realistic expectations, seeing opportunities to change the situation instead of obstacles. In the course of CES, the professionals moved from an individual interpretation of the situation to a common, new understanding and then to a change in approach. An open and permissive communication climate meant that the professionals dared to expose themselves, share their feelings, face their own emotions, and eventually arrive at a mutual shared reality. The value conflict was not only revealed but also resolved.

Effect of patients' rights training sessions for nurses on perceptions of nurses and patients.

Science.gov (United States)

Ibrahim, Sanaa A; Hassan, Mona A; Hamouda, Seham Ibrahim; Abd Allah, Nama M

2017-11-01

Patients' rights are universal values that must be respected; however, it is not easy to put such values and principles into effect as approaches and attitudes differ from individual to individual, from society to society, and from country to country. If we want to reach a general conclusion about the status of patient rights in the world as whole, we should examine the situation in individual countries. To study the effect of training sessions for nurses about patients' rights on the perceptions of nurses and patients in two Egyptian hospitals. Quasi-experimental with pre- and posttest design was used in this study. Two groups of participants were included in the study: the first with 97 nurses and the second with 135 patients. A questionnaire sheet was used for nurses and patients to assess their perceptions about patients' rights before starting sessions. The training sessions were developed based on the baseline information gathered in the assessment phase and related literature. After the implementation of the sessions, a posttest was immediately conducted for nurses, while for patients the posttest was conducted 1 month after implementation to evaluate the effect of the nurses' training sessions on the patients' perceptions. The same tools were used in pretest and posttest. Ethical considerations: Written approval was sought and obtained from the administrators of the studied hospitals prior to conducting the study. Oral consent was obtained from nurses and patients willing to participate. Confidentiality and anonymity of the participants were strictly maintained through code numbers on the questionnaires. The improvement in nurses' knowledge and perceptions about patients' rights after implementation of the training sessions was remarkable. Moreover, an improvement in patients' perceptions regarding their rights was reported. Repetition of the training sessions is suggested to achieve continuous improvement. Provision of posters and booklets about a bill of

MCNPX, MONK, and ERANOS analyses of the YALINA Booster subcritical assembly

Energy Technology Data Exchange (ETDEWEB)

Talamo, Alberto, E-mail: alby@anl.go [Argonne National Laboratory, 9700 S. Cass Avenue, Argonne, IL 60439 (United States); Gohar, Y.; Aliberti, G.; Cao, Y.; Smith, D.; Zhong, Z. [Argonne National Laboratory, 9700 S. Cass Avenue, Argonne, IL 60439 (United States); Kiyavitskaya, H.; Bournos, V.; Fokov, Y.; Routkovskaya, C.; Serafimovich, I. [Joint Institute for Power and Nuclear Research - Sosny, National Academy of Sciences of Belarus, 99 Acad. Krasin Str., Minsk 220109 (Belarus)

2011-05-15

This paper compares the numerical results obtained from various nuclear codes and nuclear data libraries with the YALINA Booster subcritical assembly (Minsk, Belarus) experimental results. This subcritical assembly was constructed to study the physics and the operation of accelerator-driven subcritical systems (ADS) for transmuting the light water reactors (LWR) spent nuclear fuel. The YALINA Booster facility has been accurately modeled, with no material homogenization, by the Monte Carlo codes MCNPX (MCNP/MCB) and MONK. The MONK geometrical model matches that of MCNPX. The assembly has also been analyzed by the deterministic code ERANOS. In addition, the differences between the effective neutron multiplication factor and the source multiplication factors have been examined by alternative calculational methodologies. The analyses include the delayed neutron fraction, prompt neutron lifetime, generation time, neutron flux profiles, and spectra in various experimental channels. The accuracy of the numerical models has been enhanced by accounting for all material impurities and the actual density of the polyethylene material used in the assembly (the latter value was obtained by dividing the total weight of the polyethylene by its volume in the numerical model). There is good agreement between the results from MONK, MCNPX, and ERANOS. The ERANOS results show small differences relative to the other results because of material homogenization and the energy and angle discretizations.The MCNPX results match the experimental measurements of the {sup 3}He(n,p) reaction rates obtained with the californium neutron source.

MCNPX, MONK, and ERANOS analyses of the YALINA Booster subcritical assembly

International Nuclear Information System (INIS)

Talamo, Alberto; Gohar, Y.; Aliberti, G.; Cao, Y.; Smith, D.; Zhong, Z.; Kiyavitskaya, H.; Bournos, V.; Fokov, Y.; Routkovskaya, C.; Serafimovich, I.

2011-01-01

This paper compares the numerical results obtained from various nuclear codes and nuclear data libraries with the YALINA Booster subcritical assembly (Minsk, Belarus) experimental results. This subcritical assembly was constructed to study the physics and the operation of accelerator-driven subcritical systems (ADS) for transmuting the light water reactors (LWR) spent nuclear fuel. The YALINA Booster facility has been accurately modeled, with no material homogenization, by the Monte Carlo codes MCNPX (MCNP/MCB) and MONK. The MONK geometrical model matches that of MCNPX. The assembly has also been analyzed by the deterministic code ERANOS. In addition, the differences between the effective neutron multiplication factor and the source multiplication factors have been examined by alternative calculational methodologies. The analyses include the delayed neutron fraction, prompt neutron lifetime, generation time, neutron flux profiles, and spectra in various experimental channels. The accuracy of the numerical models has been enhanced by accounting for all material impurities and the actual density of the polyethylene material used in the assembly (the latter value was obtained by dividing the total weight of the polyethylene by its volume in the numerical model). There is good agreement between the results from MONK, MCNPX, and ERANOS. The ERANOS results show small differences relative to the other results because of material homogenization and the energy and angle discretizations.The MCNPX results match the experimental measurements of the 3 He(n,p) reaction rates obtained with the californium neutron source.

Update on Risk Reduction Activities for a Liquid Advanced Booster for NASA's Space Launch System

Science.gov (United States)

Crocker, Andrew M.; Greene, William D.

2017-01-01

The stated goals of NASA's Research Announcement for the Space Launch System (SLS) Advanced Booster Engineering Demonstration and/or Risk Reduction (ABEDRR) are to reduce risks leading to an affordable Advanced Booster that meets the evolved capabilities of SLS and enable competition by mitigating targeted Advanced Booster risks to enhance SLS affordability. Dynetics, Inc. and Aerojet Rocketdyne (AR) formed a team to offer a wide-ranging set of risk reduction activities and full-scale, system-level demonstrations that support NASA's ABEDRR goals. During the ABEDRR effort, the Dynetics Team has modified flight-proven Apollo-Saturn F-1 engine components and subsystems to improve affordability and reliability (e.g., reduce parts counts, touch labor, or use lower cost manufacturing processes and materials). The team has built hardware to validate production costs and completed tests to demonstrate it can meet performance requirements. State-of-the-art manufacturing and processing techniques have been applied to the heritage F-1, resulting in a low recurring cost engine while retaining the benefits of Apollo-era experience. NASA test facilities have been used to perform low-cost risk-reduction engine testing. In early 2014, NASA and the Dynetics Team agreed to move additional large liquid oxygen/kerosene engine work under Dynetics' ABEDRR contract. Also led by AR, the objectives of this work are to demonstrate combustion stability and measure performance of a 500,000 lbf class Oxidizer-Rich Staged Combustion (ORSC) cycle main injector. A trade study was completed to investigate the feasibility, cost effectiveness, and technical maturity of a domestically-produced engine that could potentially both replace the RD-180 on Atlas V and satisfy NASA SLS payload-to-orbit requirements via an advanced booster application. Engine physical dimensions and performance parameters resulting from this study provide the system level requirements for the ORSC risk reduction test article

Older Adults with Mild Cognitive Impairments Show Less Driving Errors after a Multiple Sessions Simulator Training Program but Do Not Exhibit Long Term Retention.

Science.gov (United States)

Teasdale, Normand; Simoneau, Martin; Hudon, Lisa; Germain Robitaille, Mathieu; Moszkowicz, Thierry; Laurendeau, Denis; Bherer, Louis; Duchesne, Simon; Hudon, Carol

2016-01-01

The driving performance of individuals with mild cognitive impairment (MCI) is suboptimal when compared to healthy older adults. It is expected that the driving will worsen with the progression of the cognitive decline and thus, whether or not these individuals should continue to drive is a matter of debate. The aim of the study was to provide support to the claim that individuals with MCI can benefit from a training program and improve their overall driving performance in a driving simulator. Fifteen older drivers with MCI participated in five training sessions in a simulator (over a 21-day period) and in a 6-month recall session. During training, they received automated auditory feedback on their performance when an error was noted about various maneuvers known to be suboptimal in MCI individuals (for instance, weaving, omitting to indicate a lane change, to verify a blind spot, or to engage in a visual search before crossing an intersection). The number of errors was compiled for eight different maneuvers for all sessions. For the initial five sessions, a gradual and significant decrease in the number of errors was observed, indicating learning and safer driving. The level of performance, however, was not maintained at the 6-month recall session. Nevertheless, the initial learning observed opens up possibilities to undertake more regular interventions to maintain driving skills and safe driving in MCI individuals.

Feasibility for the Use of Flat Booster Reflectors in Various Photovoltaic Installations

OpenAIRE

Gelegenis, John Joachim; Axaopoulos, Petros; Misailidis, Stavros; Giannakidis, George; Samarakou, Maria; Bonaros, Bassilios

2016-01-01

The feasibility for the addition of flat booster reflectors to PV panels is techno-economically investigated for various applications (building attached PVs, ground installations, grid-connected or stand-alone units) and various PV types (mono-crystalline and amorphous silicon PV panels). A model developed to this aim is applied to optimize the parameters of the PV/reflector module and to evaluate its applicability according to the solar radiation data of Athens (Greece). The reflectors may l...

Healthy Team Healthy U: A Prospective Validation of an Evidence-based Worksite Health Promotion and Wellness Platform

Directory of Open Access Journals (Sweden)

Linn eGoldberg

2015-08-01

Full Text Available Objective: To evaluate the effects of a research tested, team-based health promotion and wellness program combined with digital technologies and implemented in a diverse worksite setting among hospital, clinic and university employees. Methods: A prospective cohort study of employees completing biometrics and questionnaires before and after the initial 12-session wellness program and its 12-session booster, one year later. Results: After both the initial intervention and booster, blood pressure and weight were reduced, with greater reductions among employees with pre-hypertension and hypertension and those with a BMI > 25. After both the initial intervention and booster, there was a significant increase in, 1 daily intake of fruit and vegetable servings; 2 days per week of > 30 minutes of exercise; 3 days per week of strength training and 4 levels of moderately vigorous and vigorous daily physical activity. Self-reported indices of depression and work related stress were reduced, while participants reported increased happiness after the initial program and booster. Post booster, average sleep quality and sleep duration increased, among higher risk employees reporting < 6 hours of daily sleep. Employees reported receiving encouragement from co-workers to engage in healthful activities, exercising with fellow employees more, and indicated they would recommend the program to co-workers. Longitudinal analysis revealed the durability of the initial intervention outcomes with further beneficial effects after the booster. Conclusion: A research-tested, comprehensive team-based health promotion and wellness program, combined with digital technologies, positively impacted employee health behaviors, mood, sleep, worker cohesion and biometrics among a diverse multi-site workforce. Positive program effects were durable, with enhanced results after the booster.

The AGS Booster high frequency rf system

International Nuclear Information System (INIS)

Sanders, R.T.; Cameron, P.; Eng, W.; Goldman, M.A.; Jablonski, E.; Kasha, D.; Keane, J.; McNerney, A.; Meth, M.; Plotkin, M.; Puglisi, M.; Ratti, A.; Spitz, R.

1991-01-01

A high level rf system, including a power amplifier and cavity, has been designed and built for the AGS Booster. It covers a frequency range of 2.4 to 4.2 MHz and will be used to accelerate high intensity protons. Low intensity polarized protons and heavy ions, to the 1.5 GeV level. A total accelerating voltage of up to 90 kV will be provided by two cavities, each having two gaps. The internally cross coupled, pushpull cavities are driven by an adjacently located power amplifier. In order to accommodate beam intensities up to 0.75 x 10 13 protons per bunch, a low plate resistance power tetrode is used. The tube anode is magnetically coupled to one of the cavity's two parallel cells. The amplifier is a grounded cathode configuration driven by a remotely located solid-state amplifier. It has been tested in the laboratory at full gap voltage with satisfactory results. 5 refs., 2 figs., 1 tab

Graph Transformation for Consolidation of Creativity Sessions Results

DEFF Research Database (Denmark)

Dolog, Peter

2010-01-01

Graph transformation approach for consolidation of creativity sessions results is part of the FP7 EU/IST project idSpace: Tooling of and training for collaborative, distributed product innovation. The goal of graph transformation approach is to provide a tool for merging results of various sessions...... (such as brainstorming sessions), which are represented as graphs, when the session participants- are physically distributed....

Review for session K - benchmarks

International Nuclear Information System (INIS)

McCracken, A.K.

1980-01-01

Eight of the papers to be considered in Session K are directly concerned, at least in part, with the Pool Critical Assembly (P.C.A.) benchmark at Oak Ridge. The remaining seven papers in this session, the subject of this review, are concerned with a variety of topics related to the general theme of Benchmarks and will be considered individually

Assessing Cognitive behavioural Therapy in Irritable Bowel (ACTIB): protocol for a randomised controlled trial of clinical-effectiveness and cost-effectiveness of therapist delivered cognitive behavioural therapy and web-based self-management in irritable bowel syndrome in adults.

Science.gov (United States)

Everitt, Hazel; Landau, Sabine; Little, Paul; Bishop, Felicity L; McCrone, Paul; O'Reilly, Gilly; Coleman, Nicholas; Logan, Robert; Chalder, Trudie; Moss-Morris, Rona

2015-07-15

Irritable bowel syndrome (IBS) affects 10-22% of the UK population, with England's annual National Health Service (NHS) costs amounting to more than £200 million. Abdominal pain, bloating and altered bowel habit affect quality of life, social functioning and time off work. Current treatment relies on a positive diagnosis, reassurance, lifestyle advice and drug therapies, but many people suffer ongoing symptoms. Cognitive behaviour therapy (CBT) and self-management can be helpful, but availability is limited. To determine the clinical- and cost-effectiveness of therapist delivered cognitive behavioural therapy (TCBT) and web-based CBT self-management (WBCBT) in IBS, 495 participants with refractory IBS will be randomised to TCBT plus treatment as usual (TAU); WBCBT plus TAU; or TAU alone. The two CBT programmes have similar content. However, TCBT consists of six, 60 min telephone CBT sessions with a therapist over 9 weeks, at home, and two 'booster' 1 hour follow-up phone calls at 4 and 8 months (8 h therapist contact time). WBCBT consists of access to a previously developed and piloted WBCBT management programme (Regul8) and three 30 min therapist telephone sessions over 9 weeks, at home, and two 'booster' 30 min follow-up phone calls at 4 and 8 months (2½ h therapist contact time). Clinical effectiveness will be assessed by examining the difference between arms in the IBS Symptom Severity Score (IBS SSS) and Work and Social Adjustment Scale (WASAS) at 12 months from randomisation. Cost-effectiveness will combine measures of resource use with the IBS SSS at 12 months and quality-adjusted life years. This trial has full ethical approval. It will be disseminated via peer reviewed publications and conference presentations. The results will enable clinicians, patients and health service planners to make informed decisions regarding the management of IBS with CBT. ISRCTN44427879. Published by the BMJ Publishing Group Limited. For permission to

Session 2: Machine studies

International Nuclear Information System (INIS)

Assmann, R.W.; Papotti, G.

2012-01-01

This document summarizes the talks and discussion that took place in the second session of the Chamonix 2012 workshop concerning results from machine studies performed in 2011. The session consisted of the following presentations: -) LHC experience with different bunch spacings by G. Rumolo; -) Observations of beam-beam effects in MDs in 2011 by W. Herr; -) Beam-induced heating/ bunch length/RF and lessons for 2012 by E. Metral; -) Lessons in beam diagnostics by R. Jones; -) Quench margins by M. Sapinski; and -) First demonstration with beam of the Achromatic Telescopic Squeeze (ATS) by S. Fartoukh. (authors)

Quantitative Index and Abnormal Alarm Strategy Using Sensor-Dependent Vibration Data for Blade Crack Identification in Centrifugal Booster Fans.

Science.gov (United States)

Chen, Jinglong; Sun, Hailiang; Wang, Shuai; He, Zhengjia

2016-05-09

Centrifugal booster fans are important equipment used to recover blast furnace gas (BFG) for generating electricity, but blade crack faults (BCFs) in centrifugal booster fans can lead to unscheduled breakdowns and potentially serious accidents, so in this work quantitative fault identification and an abnormal alarm strategy based on acquired historical sensor-dependent vibration data is proposed for implementing condition-based maintenance for this type of equipment. Firstly, three group dependent sensors are installed to acquire running condition data. Then a discrete spectrum interpolation method and short time Fourier transform (STFT) are applied to preliminarily identify the running data in the sensor-dependent vibration data. As a result a quantitative identification and abnormal alarm strategy based on compound indexes including the largest Lyapunov exponent and relative energy ratio at the second harmonic frequency component is proposed. Then for validation the proposed blade crack quantitative identification and abnormality alarm strategy is applied to analyze acquired experimental data for centrifugal booster fans and it has successfully identified incipient blade crack faults. In addition, the related mathematical modelling work is also introduced to investigate the effects of mistuning and cracks on the vibration features of centrifugal impellers and to explore effective techniques for crack detection.

Quantitative Index and Abnormal Alarm Strategy Using Sensor-Dependent Vibration Data for Blade Crack Identification in Centrifugal Booster Fans

Directory of Open Access Journals (Sweden)

Jinglong Chen

2016-05-01

Full Text Available Centrifugal booster fans are important equipment used to recover blast furnace gas (BFG for generating electricity, but blade crack faults (BCFs in centrifugal booster fans can lead to unscheduled breakdowns and potentially serious accidents, so in this work quantitative fault identification and an abnormal alarm strategy based on acquired historical sensor-dependent vibration data is proposed for implementing condition-based maintenance for this type of equipment. Firstly, three group dependent sensors are installed to acquire running condition data. Then a discrete spectrum interpolation method and short time Fourier transform (STFT are applied to preliminarily identify the running data in the sensor-dependent vibration data. As a result a quantitative identification and abnormal alarm strategy based on compound indexes including the largest Lyapunov exponent and relative energy ratio at the second harmonic frequency component is proposed. Then for validation the proposed blade crack quantitative identification and abnormality alarm strategy is applied to analyze acquired experimental data for centrifugal booster fans and it has successfully identified incipient blade crack faults. In addition, the related mathematical modelling work is also introduced to investigate the effects of mistuning and cracks on the vibration features of centrifugal impellers and to explore effective techniques for crack detection.

Breakout Sessions

CERN Multimedia

CERN. Geneva

2004-01-01

Participants are split into small groups for detailed discussion on their chosen topic. To register please click on 'See details' link from the agenda and then on the link to send an email to the session for which you would like to book. Please don't change the subject line of the email.

Motivational Interviewing to Treat Overweight Children: 24-Month Follow-Up of a Randomized Controlled Trial.

Science.gov (United States)

Broccoli, Serena; Davoli, Anna Maria; Bonvicini, Laura; Fabbri, Alessandra; Ferrari, Elena; Montagna, Gino; Panza, Costantino; Pinotti, Mirco; Storani, Simone; Tamelli, Marco; Candela, Silvia; Bellocchio, Eletta; Giorgi Rossi, Paolo

2016-01-01

Pediatrician-led motivational interviewing can be an effective way of controlling BMI in overweight children in the short term. Its long-term efficacy is unknown. The primary aim was to determine whether the short-term (12-month) impact of family pediatrician-led motivational interviews on the BMI of overweight children could be sustained in the long term (24 months), in the absence of any other intervention. Children were recruited in 2011 by family pediatricians working in the province of Reggio Emilia, Italy, and randomly allocated to receive either 5 interviews delivered over a 12-month period or usual care. Eligible participants were all 4- to 7-year-old overweight children resident in the province of Reggio Emilia who had been receiving care from the pediatrician for ≥ 12 months. The primary outcome of this study was individual variation in BMI between the baseline visit and the 24-month follow-up, assessed by pediatricians not blinded to treatment group allocation. Of 419 eligible families, 372 (89%) participated; 187 children were randomized to receive intervention and 185 to usual care. Ninety-five percent of the children attended the 12-month follow-up, and 91% attended the 24-month follow-up. After the 12-month intervention period, BMI in the intervention group increased less than in the control group (0.46 and 0.78, respectively; difference -0.32; P = .005). At the 24-month follow-up, the difference had disappeared (1.52 and 1.56, respectively; difference -0.04; P = .986). The intervention lost its effectiveness within 1 year of cessation. Sustainable boosters are required for weight control and obesity prevention. Copyright © 2016 by the American Academy of Pediatrics.

Design and A.C. loss considerations for the 60 mm dipole magnet in the High Energy Booster

International Nuclear Information System (INIS)

Snitchler, G.; Jayakumar, R.; Kovachev, V.; Orrell, D.

1991-01-01

The baseline design for the SSC High Energy Booster (HEB) has dipole bending magnets with a 50 mm aperture. A recent dynamic aperture study for the High Energy Booster (HEB) suggests that an increased aperture dipole magnet (DM) is desirable. Two cost neutral options for a 60 mm aperture HEBDM design are investigated. Field transfer function, field harmonics, and relative cost impact for these designs are presented. An analysis of the cryogenic heat load due to A.C. losses generated in the HEB ramp cycle are also reported. Included in this analysis are losses from superconductor hysteresis, yoke hysteresis, strand eddy currents, and cable eddy currents. The A.C. loss impact of 2.5 μm vs. 6 μm filament conductor is presented. Superconducting proximity effect is also considered for 2.5 μm filament conductors

CD4 T-helper cell cytokine phenotypes and antibody response following tetanus toxoid booster immunization

Science.gov (United States)

Routine methods for enumerating antigen-specific T-helper cells may not identify low-frequency phenotypes such as Th2 cells. We compared methods of evaluating such responses to identify tetanus toxoid- (TT) specific Th1, Th2, Th17 and IL10+ cells. Eight healthy subjects were given a TT booster vacci...

Model based controls and the AGS booster controls system architecture

International Nuclear Information System (INIS)

Casella, R.A.

1987-01-01

For the past three years the Accelerator Controls Section has been responsible for the development of the Heavy Ion Transfer Line (HITL) used to inject heavy ions created at the Tandem Van de Graaff into the Alternating Gradient Synchrotron (AGS). This was recognized as an opportunity to test new ideas for control of a beam line, which if successful, could be implemented in an upgrade of the existing control system for the AGS. The in place control system for the AGS consisted of DEC PDP10 computer as the primary computer interface to the accelerator via three control room consoles, and keeper of the device database. For the HITL project it was decided to make the control system a true distributed network putting more computing power down at the device level via intelligent subsystems. A network of Apollo workstations was added at the host level. Apollos run a distributed operating system and are connected to each other by the Domain Token Ring Network. The Apollos were seen as the new primary computers for consoles with each console containing at least one Apollo. These hosts and all other subsystems are connected to each other via an in house developed LAN (RELWAY). The design of the control system developed for HITL was mostly successful. The proposed AGS Booster is designed to be a synchrotron injector for the AGS. With the forthcoming development of the Booster for the AGS an opportunity has again developed to implement new ideas for accelerator control. One weakness of the HITL control system is the limited cpu power and poor debugging facilities of the stations

Flexible session management in a distributed environment

Energy Technology Data Exchange (ETDEWEB)

Miller, Zach; /Wisconsin U., Madison; Bradley, Dan; /Wisconsin U., Madison; Tannenbaum, Todd; /Wisconsin U., Madison; Sfiligoi, Igor; /Fermilab

2010-01-01

Many secure communication libraries used by distributed systems, such as SSL, TLS, and Kerberos, fail to make a clear distinction between the authentication, session, and communication layers. In this paper we introduce CEDAR, the secure communication library used by the Condor High Throughput Computing software, and present the advantages to a distributed computing system resulting from CEDAR's separation of these layers. Regardless of the authentication method used, CEDAR establishes a secure session key, which has the flexibility to be used for multiple capabilities. We demonstrate how a layered approach to security sessions can avoid round-trips and latency inherent in network authentication. The creation of a distinct session management layer allows for optimizations to improve scalability by way of delegating sessions to other components in the system. This session delegation creates a chain of trust that reduces the overhead of establishing secure connections and enables centralized enforcement of system-wide security policies. Additionally, secure channels based upon UDP datagrams are often overlooked by existing libraries; we show how CEDAR's structure accommodates this as well. As an example of the utility of this work, we show how the use of delegated security sessions and other techniques inherent in CEDAR's architecture enables US CMS to meet their scalability requirements in deploying Condor over large-scale, wide-area grid systems.

Flexible session management in a distributed environment

International Nuclear Information System (INIS)

Miller, Zach; Bradley, Dan; Tannenbaum, Todd; Sfiligoi, Igor

2010-01-01

Many secure communication libraries used by distributed systems, such as SSL, TLS, and Kerberos, fail to make a clear distinction between the authentication, session, and communication layers. In this paper we introduce CEDAR, the secure communication library used by the Condor High Throughput Computing software, and present the advantages to a distributed computing system resulting from CEDAR's separation of these layers. Regardless of the authentication method used, CEDAR establishes a secure session key, which has the flexibility to be used for multiple capabilities. We demonstrate how a layered approach to security sessions can avoid round-trips and latency inherent in network authentication. The creation of a distinct session management layer allows for optimizations to improve scalability by way of delegating sessions to other components in the system. This session delegation creates a chain of trust that reduces the overhead of establishing secure connections and enables centralized enforcement of system-wide security policies. Additionally, secure channels based upon UDP datagrams are often overlooked by existing libraries; we show how CEDAR's structure accommodates this as well. As an example of the utility of this work, we show how the use of delegated security sessions and other techniques inherent in CEDAR's architecture enables US CMS to meet their scalability requirements in deploying Condor over large-scale, wide-area grid systems.

Flexible session management in a distributed environment

Energy Technology Data Exchange (ETDEWEB)

Miller, Zach; Bradley, Dan; Tannenbaum, Todd [University of Wisconsin, Madison, WI (United States); Sfiligoi, Igor, E-mail: zmiller@cs.wisc.ed [Fermi National Acceleartor Laboratory, Batavia, IL (United States)

2010-04-01

Many secure communication libraries used by distributed systems, such as SSL, TLS, and Kerberos, fail to make a clear distinction between the authentication, session, and communication layers. In this paper we introduce CEDAR, the secure communication library used by the Condor High Throughput Computing software, and present the advantages to a distributed computing system resulting from CEDAR's separation of these layers. Regardless of the authentication method used, CEDAR establishes a secure session key, which has the flexibility to be used for multiple capabilities. We demonstrate how a layered approach to security sessions can avoid round-trips and latency inherent in network authentication. The creation of a distinct session management layer allows for optimizations to improve scalability by way of delegating sessions to other components in the system. This session delegation creates a chain of trust that reduces the overhead of establishing secure connections and enables centralized enforcement of system-wide security policies. Additionally, secure channels based upon UDP datagrams are often overlooked by existing libraries; we show how CEDAR's structure accommodates this as well. As an example of the utility of this work, we show how the use of delegated security sessions and other techniques inherent in CEDAR's architecture enables US CMS to meet their scalability requirements in deploying Condor over large-scale, wide-area grid systems.

Flexible session management in a distributed environment

Science.gov (United States)

Miller, Zach; Bradley, Dan; Tannenbaum, Todd; Sfiligoi, Igor

2010-04-01

Many secure communication libraries used by distributed systems, such as SSL, TLS, and Kerberos, fail to make a clear distinction between the authentication, session, and communication layers. In this paper we introduce CEDAR, the secure communication library used by the Condor High Throughput Computing software, and present the advantages to a distributed computing system resulting from CEDAR's separation of these layers. Regardless of the authentication method used, CEDAR establishes a secure session key, which has the flexibility to be used for multiple capabilities. We demonstrate how a layered approach to security sessions can avoid round-trips and latency inherent in network authentication. The creation of a distinct session management layer allows for optimizations to improve scalability by way of delegating sessions to other components in the system. This session delegation creates a chain of trust that reduces the overhead of establishing secure connections and enables centralized enforcement of system-wide security policies. Additionally, secure channels based upon UDP datagrams are often overlooked by existing libraries; we show how CEDAR's structure accommodates this as well. As an example of the utility of this work, we show how the use of delegated security sessions and other techniques inherent in CEDAR's architecture enables US CMS to meet their scalability requirements in deploying Condor over large-scale, wide-area grid systems.

A two-session psychological intervention for siblings of pediatric cancer patients: a randomized controlled pilot trial

Directory of Open Access Journals (Sweden)

Prchal Alice

2012-01-01

Full Text Available Abstract Background Since siblings of pediatric cancer patients are at risk for emotional, behavioral, and social problems, there is considerable interest in development of early psychological interventions. This paper aimed at evaluating the effectiveness of a two-session psychological intervention for siblings of newly diagnosed pediatric cancer patients. Methods Thirty siblings age 6-17 years were randomly assigned to an intervention group or an active control group with standard psychosocial care. The manualized intervention provided to siblings in the first 2 months after the cancer diagnosis of the ill child included medical information, promotion of coping skills, and a psychoeducational booklet for parents. At 4 to 6 weeks, 4 months, and 7 months after the diagnosis, all siblings and their parents completed measures (from standardized instruments of social support, quality of life, medical knowledge, posttraumatic stress symptoms, and anxiety. Results At follow-up siblings in the intervention group showed better psychological well-being, had better medical knowledge, and reported receiving social support from more people. However, the intervention had no effects on posttraumatic stress symptoms and anxiety. Conclusions The results of this pilot trial suggest that a two-session sibling intervention can improve siblings' adjustment, particularly psychological well-being, in the early stage after a cancer diagnosis. Trial Registration ClinicalTrials.gov NCT00296907

Making the Case for Reusable Booster Systems: The Operations Perspective

Science.gov (United States)

Zapata, Edgar

2012-01-01

Presentation to the Aeronautics Space Engineering Board National Research Council Reusable Booster System: Review and Assessment Committee. Addresses: the criteria and assumptions used in the formulation of current RBS plans; the methodologies used in the current cost estimates for RBS; the modeling methodology used to frame the business case for an RBS capability including: the data used in the analysis, the models' robustness if new data become available, and the impact of unclassified government data that was previously unavailable and which will be supplied by the USAF; the technical maturity of key elements critical to RBS implementation and the ability of current technology development plans to meet technical readiness milestones.

Session summaries

International Nuclear Information System (INIS)

Sudo, Y.

2002-01-01

In the summary session, possible international activities in the field of basic studies on high-temperature engineering were discussed within the framework of the OECD/NEA Nuclear Science Committee (NSC). It was recommended to include topics relevant to fission-product behaviour and safety issues of HTGR in next meeting, in addition to the topics discussed in this meeting. The chairperson of the last session summarised the recommendations to be presented to the NSC into the following five topics as possible international activities: - Basic studies on behaviour of irradiated graphite/carbon and ceramic materials including their composites under both operation and storage conditions. - Development of in-core material characterisation and instrumentation methods. - Improvement in material properties through high-temperature irradiation. - Basic studies on HTGR fuel fabrication and performance including fission-product release. - Basic studies on safety issues of HTGR. It was also recommended that a further information exchange meeting focused on the organisation of the interactive collaboration activity with regard to the above topics be planned in 2003, tentatively in Oarai, Japan. (author)

Online Measurement of the Energy Spread of Multi-Turn Beam in the Fermilab Booster at Injection

Energy Technology Data Exchange (ETDEWEB)

Nelson, J. [Brown U.; Bhat, C. M. [Fermilab; Hendricks, B. S. [Fermilab

2017-07-01

We have developed a computer program interfaced with the ACNET environment of Fermilab accelerators to measure energy spread of the proton beam from the LINAC at an injection into the Booster. It uses a digitizing oscilloscope and provides users an ability to configure the scope settings for optimal data acquisition from a resistive wall current monitor. When the program is launched, a) a one shot timeline is generated to initiate beam injection into the Booster, b) a gap of about 40 ns is produced in the injected beam using a set of fast kickers, c) collects line charge distribution data from the wall current monitor for the first 200 μs from the injection and d) performs complete data analysis to extract full beam energy spread of the beam. The program also gives the option to store the data for offline analyses. We illustrate a case with an example. We also present results on beam energy spread as a function of beam intensity from recent measurements.

Immune responses and safety after dart or booster vaccination of bison with Brucella abortus strain RB51

Science.gov (United States)

One alternative in the Bison remote vaccination environmental impact statement (EIS) for Yellowstone National Park includes inoculation of both calves and yearlings. Although RB51 vaccination of bison does protect against experimental challenge, it was unknown whether booster vaccination might enhan...

Beam dynamics calculations for the linac booster beam line

International Nuclear Information System (INIS)

Lu, J.Q.; Cramer, J.G.; Storm, D.W.

1987-01-01

Beam optics focusing characteristics both in the transverse and longitudinal directions of the superconducting linac booster beam line are calculated for different particles. Three computer programs, which are TRANSPORT, LYRA and ENTIME, are used to simulate particle motions. The first one is used to simulate the particle radial motions. The effects of energy increase on to the transverse phase space area are considered by putting in accelerating matrices of each resonators. The second program is used to simulate particle longitudinal motions. Beam longitudinal motions are calculated with program ENTIME also, with which visual pictures in the Energy-Time phase space can be displayed on the terminal screen. Besides, the stability of the particle periodic motions in the radial directions are considered and calculated

Evaluating an intervention to reduce fear of falling and associated activity restriction in elderly persons: design of a randomised controlled trial [ISRCTN43792817

Directory of Open Access Journals (Sweden)

van Eijk JThM

2005-03-01

Full Text Available Abstract Background Fear of falling and associated activity restriction is common in older persons living in the community. Adverse consequences of fear of falling and associated activity restriction, like functional decline and falls, may have a major impact on physical, mental and social functioning of these persons. This paper presents the design of a trial evaluating a cognitive behavioural group intervention to reduce fear of falling and associated activity restriction in older persons living in the community. Methods/design A two-group randomised controlled trial was developed to evaluate the intervention. Persons 70 years of age or over and still living in the community were eligible for study if they experienced at least some fear of falling and associated activity restriction. A random community sample of elderly people was screened for eligibility; those eligible for study were measured at baseline and were subsequently allocated to the intervention or control group. Follow-up measurements were carried out directly after the intervention period, and then at six months and 12 months after the intervention. People allocated to the intervention group were invited to participate in eight weekly sessions of two hours each and a booster session. This booster session was conducted before the follow-up measurement at six months after the intervention. People allocated to the control group received no intervention as a result of this trial. Both an effect evaluation and a process evaluation were performed. The primary outcome measures of the effect evaluation are fear of falling, avoidance of activity due to fear of falling, and daily activity. The secondary outcome measures are perceived general health, self-rated life satisfaction, activities of daily life, feelings of anxiety, symptoms of depression, social support interactions, feelings of loneliness, falls, perceived consequences of falling, and perceived risk of falling. The outcomes of

Investigation and Verification of the Aerodynamic Performance of a Fan/Booster with Through-flow Method

Science.gov (United States)

Liu, Xiaoheng; Jin, Donghai; Gui, Xingmin

2018-04-01

Through-flow method is still widely applied in the revolution of the design of a turbomachinery, which can provide not merely the performance characteristic but also the flow field. In this study, a program based on the through-flow method was proposed, which had been verified by many other numerical examples. So as to improve the accuracy of the calculation, abundant loss and deviation models dependent on the real geometry of engine were put into use, such as: viscous losses, overflow in gaps, leakage from a flow path through seals. By means of this program, the aerodynamic performance of a certain high through-flow commercial fan/booster was investigated. On account of the radial distributions of the relevant parameters, flow deterioration in this machine was speculated. To confirm this surmise, 3-D numerical simulation was carried out with the help of the NUMECA software. Through detailed analysis, the speculation above was demonstrated, which provide sufficient evidence for the conclusion that the through-flow method is an essential and effective method for the performance prediction of the fan/booster.

Results of Combined, Single-Session Arthrocentesis and Dextrose Prolotherapy for Symptomatic Temporomandibular Joint Syndrome: A Case Series.

Science.gov (United States)

Cezairli, Burak; Sivrikaya, Efe Can; Omezli, Mehmet Melih; Ayranci, Ferhat; Seyhan Cezairli, Neslihan

2017-10-01

Arthrocentesis and prolotherapy are nonsurgical treatments for temporomandibular joint (TMJ) diseases. This study aimed to evaluate the treatment of hypermobility, pain, and displacement of the TMJ by consecutively performing arthrocentesis and prolotherapy in the same session. In this study, 10 adults with disc displacement and painful, hypermobile TMJ were selected. Arthrocentesis and prolotherapy were consecutively performed using a 30% dextrose solution that was simultaneously injected into five areas: posterior disc attachment, superior joint space, superior and inferior capsular attachments, and stylomandibular ligament. Paired t-test, McNemar test, and chi-square test were used to assess the maximum mouth opening, clicking sounds, pain, and subluxation of the TMJ. Patients with rheumatoid arthritis and parafunctional habits such as teeth clenching and grinding and biting of the cheeks or any other objects and those who had undergone surgery were excluded from this study. A total of 10 participants (36.20 ± 7.06 years old, 7 women and 3 men) received a single treatment session of combined arthrocentesis and prolotherapy at the same office visit. Subluxation frequency and pain significantly decreased after the first week of treatment (p < 0.05). Subluxation also decreased at the 3-month follow-up (p < 0.05). Clicking sound values did not significantly change at any of the follow-up time points. Maximum mouth opening values decreased at all follow-up time points compared to baseline (p < 0.05). A single session of combined arthrocentesis and prolotherapy to treat symptomatic TMJ safely and significantly improved the subluxation and pain after 1 week and subluxation after 3 months compared to baseline status. The maximum mouth opening significantly decreased at all follow-up time points. Future studies assessing multiple treatment sessions are warranted.

Ethics case reflection sessions: Enablers and barriers.

Science.gov (United States)

Bartholdson, Cecilia; Molewijk, Bert; Lützén, Kim; Blomgren, Klas; Pergert, Pernilla

2018-03-01

In previous research on ethics case reflection (ECR) sessions about specific cases, healthcare professionals in childhood cancer care were clarifying their perspectives on the ethical issue to resolve their main concern of consolidating care. When perspectives were clarified, consequences in the team included 'increased understanding', 'group strengthening' and 'decision grounding'. Additional analysis of the data was needed on conditions that could contribute to the quality of ECR sessions. The aim of this study was to explore conditions for clarifying perspectives during ECR sessions. Data were collected from observations and interviews and the results emerged from an inductive analysis using grounded theory. Participants and research context: Six observations during ECR sessions and 10 interviews were performed with healthcare professionals working in childhood cancer care and advanced paediatric homecare. Ethical considerations: The study was approved by a regional ethical review board. Participants were informed about their voluntary involvement and that they could withdraw their participation without explaining why. Two categories emerged: organizational enablers and barriers and team-related enablers and barriers. Organizational enablers and barriers included the following sub-categories: the timing of the ECR session, the structure during the ECR session and the climate during the ECR session. Sub-categories to team-related enablers and barriers were identified as space for inter-professional perspectives, varying levels of ethical skills and space for the patient's and the family's perspectives. Space for inter-professional perspectives included the dominance of a particular perspective that can result from hierarchical positions. The medical perspective is relevant for understanding the child's situation but should not dominate the ethical reflection. Conditions for ECR sessions have been explored and the new knowledge can be used when training

Multiparty session types as coherence proofs

DEFF Research Database (Denmark)

Carbone, Marco; Montesi, Fabrizio; Schürmann, Carsten

2017-01-01

We propose a Curry–Howard correspondence between a language for programming multiparty sessions and a generalisation of Classical Linear Logic (CLL). In this framework, propositions correspond to the local behaviour of a participant in a multiparty session type, proofs to processes, and proof nor...

BILATERAL SINGLE SESSION URETEROSCOPY FOR URETERAL ...

African Journals Online (AJOL)

Objectives: To determine the feasibility, safety and success rate of bilateral single session rigid retrograde ureteroscopy (URS) for bilateral ureteral calculi. Patients and Methods: Thirty-five patients underwent bilateral single session ureteroscopic calculus removal. Results: Out of 70 renal units in 35 patients treated, ...

Stennis observes Women's History Month

Science.gov (United States)

2010-01-01

NASA John C. Stennis Space Center employees observed Women's History Month on March 17 with a panel discussion that featured accomplished women of the facility. The gathering featured (l to r): Pam Covington, manager of the NASA Office of External Affairs at Stennis; Mary Jones, assistant chief of staff with the Navy Meterology & Oceanography Command; and Lauren Underwood, senior research scientist with Science Systems and Applications, Inc. In addition to the panel discussion, the Stennis Diversity Council and Patriot Technologies also hosted a pair of 'lunch-and-learn' sessions focused on women's issues and history. The luncheons featured videos on Sally Hemings, the slave widely recognized as the mistress of President Thomas Jefferson; and several mothers of U.S. presidents.

Semi-Automated Discovery of Application Session Structure

Energy Technology Data Exchange (ETDEWEB)

Kannan, J.; Jung, J.; Paxson, V.; Koksal, C.

2006-09-07

While the problem of analyzing network traffic at the granularity of individual connections has seen considerable previous work and tool development, understanding traffic at a higher level---the structure of user-initiated sessions comprised of groups of related connections---remains much less explored. Some types of session structure, such as the coupling between an FTP control connection and the data connections it spawns, have prespecified forms, though the specifications do not guarantee how the forms appear in practice. Other types of sessions, such as a user reading email with a browser, only manifest empirically. Still other sessions might exist without us even knowing of their presence, such as a botnet zombie receiving instructions from its master and proceeding in turn to carry them out. We present algorithms rooted in the statistics of Poisson processes that can mine a large corpus of network connection logs to extract the apparent structure of application sessions embedded in the connections. Our methods are semi-automated in that we aim to present an analyst with high-quality information (expressed as regular expressions) reflecting different possible abstractions of an application's session structure. We develop and test our methods using traces from a large Internet site, finding diversity in the number of applications that manifest, their different session structures, and the presence of abnormal behavior. Our work has applications to traffic characterization and monitoring, source models for synthesizing network traffic, and anomaly detection.

Maternal communicative functions and mind-mindedness at 16 months as predictors of children's internal and non-internal language at 20 months.

Science.gov (United States)

Longobardi, Emiddia; Spataro, Pietro; Colonnesi, Cristina

2018-02-01

The effects of Communicative functions and Mind-Mindedness on children's language development have been typically investigated in separate studies. The present longitudinal research was therefore designed to yield new insight into the simultaneous impact of these two dimensions of maternal responsiveness on the acquisition of expressive language skills in a sample of 25 mother-child dyads. The frequencies of five communicative functions (Tutorial, Didactic, Conversational, Control and Asynchronous) and two types of mind-related comments (attuned vs. non-attuned) were assessed from a 15-min play session at 16 months. Children's expressive language was examined at both 16 months (number of word types and tokens produced, and number of words attributed to the child in the Questionnaire for Communication and Early Language development) and 20 months (number of internal and non-internal words attributed to the child in the Italian version of the Mac Arthur-Bates Communicative Development Inventory). The main finding was that mothers' use of attuned mind-related comments at 16 months predicted internal state language at 20 months, above and beyond the effects of CFs and children's linguistic ability at 16 months; in addition, mothers' Tutorial function at 16 months marginally predicted non-internal state language at 20 months, after controlling for MM and children's linguistic ability at 16 months. These results suggest that different expressions of maternal responsiveness influence distinct aspects of children's expressive language in the second year of life, although the effects of MM appear to be more robust. Copyright © 2017 Elsevier Inc. All rights reserved.

First-in-human safety and immunogenicity investigations of three adjuvanted reduced dose inactivated poliovirus vaccines (IPV-Al SSI) compared to full dose IPV Vaccine SSI when given as a booster vaccination to adolescents with a history of IPV vaccination at 3, 5, 12months and 5years of age.

Science.gov (United States)

Lindgren, Line M; Tingskov, Pernille N; Justesen, Annette H; Nedergaard, Bettina S; Olsen, Klaus J; Andreasen, Lars V; Kromann, Ingrid; Sørensen, Charlotte; Dietrich, Jes; Thierry-Carstensen, Birgit

2017-01-23

There is a demand of affordable IPV in the World. Statens Serum Institut (SSI) has developed three reduced dose IPV formulations adsorbed to aluminium hydroxide; 1/3 IPV-Al, 1/5 IPV-Al and 1/10 IPV-Al SSI, and now report the results of the first investigations in humans. 240 Danish adolescents, aged 10-15years, and childhood vaccinated with IPV were booster vaccinated with 1/3 IPV-Al, 1/5 IPV-Al, 1/10 IPV-Al or IPV Vaccine SSI. The booster effects (GMTRs) of the three IPV-Al SSI were compared to IPV Vaccine SSI, and evaluated for non-inferiority. The pre-vaccination GMTs were similar across the groups; 926 (type 1), 969 (type 2) and 846 (type 3) in the total trial population. The GMTRs by poliovirus type and IPV formulation were: Type 1: 17.0 (1/3 IPV-Al), 13.0 (1/5 IPV-Al), 7.1 (1/10 IPV-Al) and 42.2 (IPV Vaccine SSI). Type 2: 12.5 (1/3 IPV-Al), 13.1 (1/5 IPV-Al), 7.6 (1/10 IPV-Al) and 47.8 (IPV Vaccine SSI). Type 3: 14.5 (1/3 IPV-Al), 16.2 (1/5 IPV-Al), 8.9 (1/10 IPV-Al) and 62.4 (IPV Vaccine SSI) Thus, the three IPV-Al formulations were highly immunogenic, but inferior to IPV Vaccine SSI, in this booster vaccination trial. No SAE and no AE of severe intensity occurred. 59.2% of the subjects reported at least one AE. Injection site pain was the most frequent AE in all groups; from 24.6% to 43.3%. Injection site redness and swelling frequencies were<5% in most and<10% in all groups. The most frequent systemic AEs were fatigue (from 8.2% to 15.0%) and headache (from 15.0% to 28.3%). Most AEs were of mild intensity. In conclusion, the three IPV-Al SSI were safe in adolescents and the booster effects were satisfactory. ClinicalTrials.gov registration number: NCT02280447. Copyright © 2016. Published by Elsevier Ltd.

Dataset of acute repeated sessions of bifrontal transcranial direct current stimulation for treatment of intractable tinnitus: A randomized controlled trial

Directory of Open Access Journals (Sweden)

Ali Yadollahpour

2017-12-01

Full Text Available Transcranial direct current stimulation (tDCS has reportedly shown promising therapeutic effects for tinnitus (Forogh et al., 2016; Joos et al., 2014 [1,2]. Studies are ongoing to determine optimum treatment protocol and the site of stimulation. Findings of the early studies are heterogeneous and most studies have focused on single session tDCS and short follow-up periods. There is no study on repeated sessions of tDCS with long term follow-up. This study presents the results of a randomized clinical trial investigating the therapeutic effects of acute multi-session tDCS over dorsolateral prefrontal cortex (DLPFC on tinnitus symptoms and comorbid depression and anxiety in patients with chronic intractable tinnitus. The dataset includes the demographic information, audiometric assessments, tinnitus specific characteristics, and the response variables of the study. The response variables included the scores of tinnitus handicap inventory (THI, tinnitus loudness and tinnitus related distress based on 0–10 numerical visual analogue scale (VAS scores, beck depression inventory (BDI-II and beck anxiety inventory (BAI scores. The dataset included the scores of THI pre and immediately post intervention, and at one month follow-up; the tinnitus loudness and distress scores prior to intervention, and immediately, one hour, one week, and at one month after the last stimulation session. In addition, the BDI-II, and BAI scores pre and post intervention are included. The data of the real (n=25 and sham tDCS (n=17 groups are reported. The main manuscript of this dataset is 'Acute repeated sessions of bifrontal transcranial direct current stimulation for treatment of intractable tinnitus: a randomized controlled trial' (Bayat et al., submitted for publication [3]. Keywords: Transcranial direct current stimulation, Acute stimulations, Tinnitus, Depression, Anxiety, DLPFC

Design and A.C. loss considerations for the 60 mm dipole magnet in the high energy booster

International Nuclear Information System (INIS)

Snitchler, G.; Jayakumar, R.; Kovachev, V.; Orrell, D.

1991-04-01

The baseline design for the SSC High Energy Booster (HEB) has dipole bending magnets with a 50 mm aperture. A recent dynamic aperture study for the High Energy Booster (HEB) suggests that an increased aperture dipole magnet (DM) is desirable. Two cost neutral options for a 60 mm aperture HEBDM design are investigated. Field transfer function, field harmonics, and relative cost impact for these designs are presented. An analysis of the cryogenic heat and load due to A.C. losses generated in the HEB ramp cycle are also reported. Included in this analysis are losses from superconductor hysteresis, yoke hysteresis, strand eddy currents, and cable eddy currents. The A.C. loss impact of 2.5 μm vs. 6 μm filament conductor will be presented. Superconducting proximity effect is also considered for 2.5 μm filament conductors. 13 refs., 3 figs., 7 tabs

Child- and family-focused cognitive-behavioral therapy for pediatric bipolar disorder: a randomized clinical trial.

Science.gov (United States)

West, Amy E; Weinstein, Sally M; Peters, Amy T; Katz, Andrea C; Henry, David B; Cruz, Rick A; Pavuluri, Mani N

2014-11-01

Previous studies have found that family-based psychosocial treatments are effective adjuncts to pharmacotherapy among adults and adolescents with bipolar disorder (BD). The objective of this study was to compare the efficacy of adjunctive child- and family-focused cognitive-behavioral therapy (CFF-CBT) to psychotherapy as usual (control) for mood symptom severity and global functioning in children with BD. Sixty-nine youth, aged 7 to 13 years (mean = 9.19, SD = 1.61) with DSM-IV-TR bipolar I, II, or not otherwise specified (NOS) disorder were randomly assigned to CFF-CBT or control groups. Both treatments consisted of 12 weekly sessions followed by 6 monthly booster sessions delivered over a total of 9 months. Independent evaluators assessed participants at baseline, week 4, week 8, week 12 (posttreatment), and week 39 (6-month follow-up). Participants in CFF-CBT attended more sessions, were less likely to drop out, and reported greater satisfaction with treatment than controls. CFF-CBT demonstrated efficacy compared to the control treatment in reducing parent-reported mania at posttreatment and depression symptoms at posttreatment and follow-up. Global functioning did not differ at posttreatment but was higher among CFF-CBT participants at follow-up. CFF-CBT may be efficacious in reducing acute mood symptoms and improving long-term psychosocial functioning among children with BD. Copyright © 2014 American Academy of Child and Adolescent Psychiatry. Published by Elsevier Inc. All rights reserved.

A Monte Carlo Analysis of the Thrust Imbalance for the RSRMV Booster During Both the Ignition Transient and Steady State Operation

Science.gov (United States)

Foster, Winfred A., Jr.; Crowder, Winston; Steadman, Todd E.

2014-01-01

This paper presents the results of statistical analyses performed to predict the thrust imbalance between two solid rocket motor boosters to be used on the Space Launch System (SLS) vehicle. Two legacy internal ballistics codes developed for the Space Shuttle program were coupled with a Monte Carlo analysis code to determine a thrust imbalance envelope for the SLS vehicle based on the performance of 1000 motor pairs. Thirty three variables which could impact the performance of the motors during the ignition transient and thirty eight variables which could impact the performance of the motors during steady state operation of the motor were identified and treated as statistical variables for the analyses. The effects of motor to motor variation as well as variations between motors of a single pair were included in the analyses. The statistical variations of the variables were defined based on data provided by NASA's Marshall Space Flight Center for the upgraded five segment booster and from the Space Shuttle booster when appropriate. The results obtained for the statistical envelope are compared with the design specification thrust imbalance limits for the SLS launch vehicle

COMMISSIONING RESULTS OF SLOW EXTRACTION OF HEAVY IONS from THE AGS BOOSTER

International Nuclear Information System (INIS)

BROWN, K.A.; AHRENS, L.; BELLAVIA, S.; BINELLO, S.; BRELSFORD, B.; DUMONT, D.; ENG, W.; GARDNER, C.; GASSNER, D.; GLENN, J.W.; HAMMONS, L.; HOCK, J.; HOFF, L.; HUTCHINSON, E.; JAMILKOWSKI, J.; KLING, N.; KOTLYAR, Y.; KRISHOCK, A.; LOCKEY, R.; MAPES, M.; MARNERIS, I.; MARR, G.; MCNERNEY, A.; MEYER, A.; MORRIS, J.; NAYLOR, C.; NEMESURE, S.; PHILLIPS, D.; RUSEK, A.; RYAN, J.; SHREY, T.; SNYDSTRUP, L.; TSOUPAS, N.; VANKUIK, B.; ZAHARIOU-COHEN, K.; ZENO, K.

2003-01-01

Brookhaven's AGS Booster has been modified to deliver slow extracted beam to a new beam line, the NASA Space Radiation Laboratory (NSRL). This facility was constructed in collaboration with NASA for the purpose of performing radiation effect studies for the NASA space program. The design of the resonant extraction system has been described in [1]. A more detailed description, which includes predictions of the slow extracted beam time structure has been described in [2]. In this report we will present results of the system commissioning and performance

Human Reliability Analysis: session summary

International Nuclear Information System (INIS)

Hall, R.E.

1985-01-01

The use of Human Reliability Analysis (HRA) to identify and resolve human factors issues has significantly increased over the past two years. Today, utilities, research institutions, consulting firms, and the regulatory agency have found a common application of HRA tools and Probabilistic Risk Assessment (PRA). The ''1985 IEEE Third Conference on Human Factors and Power Plants'' devoted three sessions to the discussion of these applications and a review of the insights so gained. This paper summarizes the three sessions and presents those common conclusions that were discussed during the meeting. The paper concludes that session participants supported the use of an adequately documented ''living PRA'' to address human factors issues in design and procedural changes, regulatory compliance, and training and that the techniques can produce cost effective qualitative results that are complementary to more classical human factors methods

Undergraduate Researchers and the Poster Session

Science.gov (United States)

Johnson, Gail; Green, Raymond

2007-01-01

Undergraduates presented original research in classroom poster sessions open to students, faculty, and friends. We assessed the reaction of the students to the experience and their reported change in their interest in presenting at conferences. Students enjoyed the poster session experience and indicated they preferred this method over other…

Ann Arbor Session I: Breaking Ground.

Science.gov (United States)

Music Educators Journal, 1979

1979-01-01

Summarizes the first session of the National Symposium on the Applications of Psychology to the Teaching and Learning of Music held at Ann Arbor from October 30 to November 2, 1978. Sessions concerned auditory perception, motor learning, child development, memory and information processing, and affect and motivation. (SJL)

An ecological model to factors associated with booster seat use: A population based study.

Science.gov (United States)

Shimony Kanat, Sarit; Gofin, Rosa

2017-11-01

Belt-positioning booster seat use (BPB) is an effective technology to prevent severe child injury in cases of car crash. However, in many countries, age-appropriate car restraint use for children aged 4-7 years old remains the lowest among all age groups. The aim of this study was to identify the main determinants of BPB use through a comprehensive approach. An ecological model was used to analyze individual, parent-child relationships, and neighborhood characteristics. Parents of children enrolled in the first and second grades completed a self-reported questionnaire (n=745). The data were subjected to multilevel modeling. The first level examined individual and parent-child relationship variables; in addition the second level tested between neighborhood variance. According to parental self- reports, 56.6% of their children had used a BPB on each car trip during the previous month. The results indicated that the determinants positively related to BPB use were individual and parental; namely, the number of children in the family, the parents' car seat belt use, parental knowledge of children's car safety principles, and a highly authoritative parenting style. Children's temperaments and parental supervision were not associated with BPB use. At the neighborhood level, a small difference was found between neighborhoods for BPB users compared to non-users. Copyright © 2017 Elsevier Ltd. All rights reserved.

Status of rf development work on a ferrite tuned amplifier cavity for the TRIUMF KAON factory booster ring

International Nuclear Information System (INIS)

Poirier, R.L.; Enegren, T.

1987-01-01

Of the five synchrotron rings in the proposed TRIUMF KAON factory, the Booster ring to accelerate the proton beam from 440 MeV to 3 GeV has the most demanding rf requirements, primarily because of the relatively large frequency swing of 46.1 MHz to 61.1 MHz at a high repetition rate of 50 Hz. In the current reference design, the Booster lattice has twelve 3.9 m drift spaces with 2.5 m in each drift space available for installation of rf cavities to provide a required effective acceleration voltage of up to 600 kV per turn i.e. 50 kV per cavity. Design and development studies of a suitable cavity-amplifier system are in progress. For the initial reference design a system based on the one used in the Fermilab booster synchrotron has been chosen. That is, a double-gap drift-tube cavity with parallel-biased ferrite tuners and excited with a directly coupled Eimac Y567B tetrode. To meet the tuning and voltage requirements within the various mechanical and other constraints such as tube-to-gap voltage ratio, ferrite power density and available space, the reference design had to be further modified and a cold model of the cavity and tuners was constructed from copper-covered cardboard cylinders. From the results of the cold model measurements a new reference design was established and design work has begun on a full power prototype of the cavity-amplifier system

Summary of southeastern group breakout sessions

Science.gov (United States)

Bob Ford; Charles P. Nicholson

1993-01-01

The breakout sessions held by the southeastern representatives at the Partners In Flight meeting in Colorado were extremely well attended Most states were represented, as well as several federal agencies (including USFS, USFWS, TVA, EPA), and non-government organizations. Two sessions were held, one to discuss a strategy of management by...

Session Introduction

Science.gov (United States)

Eliane Lessner, Co-Chair:

2009-03-01

A panel discussion session providing a worldwide assessment of the status and experiences of women in physics, paying attention to the different cultures and environments they work in and to how the age of the physicist affects their perspective. We will hear about women physicists in Korea in particular and Asia in general, in Egypt in particular and Africa in general, and in the Caribbean. Six invited speakers will present analyses of the progress being made in promoting women in physics from their personal experiences and as assessed from their participation in the Third International Conference on Women In Physics (ICWIP2008) convened in Seoul, Korea in October 2008. From Albania to Zimbabwe, with representation of all the continents, ICWIP2008 congregated 283 women and men physicists from 57 countries to share the participants' scientific accomplishments and evaluate international progress in improving the status of women in physics. This three-hour session is organized jointly by the Committee on the Status of Women in Physics of the APS (CSWP) and the Forum on International Physics of the APS (FIP). Audience participation in the panel discussion will be strongly encouraged.

Topical Session on Materials Management

International Nuclear Information System (INIS)

2002-01-01

At its second meeting, in Paris, 5-7 December 2001, the WPDD held two topical sessions on the D and D Safety Case and on the Management of Materials from D and D, respectively. This report documents the topical session on the management of materials. Presentations during the topical session covered key aspects of the management of materials and meant to provide an exchange of information and experience, including: Experience and lessons learnt from VLLW and non-radioactive material management in Spain and Germany with special attention to recycling (How specific solutions came about? Are there 'generic' examples for wider adoption?); Risk assessment of recycling and non-recycling: a CPD study; Waste acceptance issues within different national contexts (What constraints are there on the waste receiving body and what flexibility can the latter have? What constraints does this impose on D and D implementers? What about wastes are without current solution? What needs to be done? What about large items and 'difficult' waste in general?); Radiological characterisation of materials during decommissioning, particularly difficult situations - large volumes, large items,.. wastes, heterogeneous streams (What examples of established practice? What are the approaches or aspects that set the regulatory requirements? How can the flow rates be large but the answers acceptable? How much is needed to be known for later action, e. g., disposal, release, protection of worker, etc.); Radiological characterisation of buildings as they stand, in order to allow conventional demolition (What are strategies for optimisation of characterisation? How much needs to be known to take action later? e.g. for storage, disposal, release, cost estimation and ALARA? What needs to be done in advance and after decommissioning/dismantling?). At the end of each presentation time was allotted for discussion of the paper. Integral to the Topical Session was a facilitated plenary discussion on the topical

Session 8: biofuels; Session 8: Les biocarburants

Energy Technology Data Exchange (ETDEWEB)

Botte, J.M.

2006-01-15

Here are given the summaries of the speeches of Mr Daniel Le Breton (Total): the transports of the future: the role of biofuels; of Mr Pierre Rouveirolles (Renault): the future expectations and needs; of Mr Frederic Monot (IFP): the developments of new generations of biofuels from biomass; of Mr Willem Jan Laan (Unilever): the use of bio resources for food and fuel: a fair competition? All these speeches have been presented at the AFTP yearly days (12-13 october 2005) on the session 8 concerning the biofuels. (O.M.)

Bench measurements of coupling impedance of AGS Booster components

International Nuclear Information System (INIS)

Ratti, A.; Shea, T.J.

1991-01-01

Quantifying instability thresholds for modern synchrotrons and storage rings requires some knowledge of the accelerator's coupling impedance. To this end, the wire technique has been implemented to measure the longitudinal coupling impedance of AGS Booster devices. The techniques are being refined to allow measurement of RHIC devices at higher frequencies. All the measurements are performed using an HP 8753 Network Analyzer controlled via GPIB by a Macintosh computer. The computer provides an environment for automated data acquisition, data analysis, and report generation. Resistive matches between the 50ω analyzer cables and the 300ω pipe-and-wire structure allow the use of a simple response calibration in the measurement of S21 to 400MHz. Results from ferrite loaded rf cavities, position monitors and kickers are presented. 4 refs., 4 figs

The new frontier in muscular dystrophy research: booster genes

DEFF Research Database (Denmark)

Engvall, Eva; Wewer, Ulla M

2003-01-01

More than 30 different forms of muscular dystrophy (MD) have been molecularly characterized and can be diagnosed, but progress toward treatment has been slow. Gene replacement therapy has met with great difficulty because of the large size of the defective genes and because of difficulties...... of the boosters are better understood, drugs may be developed to provide the boost to muscle. Some of the experiences in models of muscular dystrophy may inspire new approaches in other genetic degenerative diseases as well....... in delivering a gene to all muscle groups. Cell replacement therapy has also been difficult to realize. Will it even be possible to design specific therapy protocols for all MDs? Or is a more realistic goal to treat some of the secondary manifestations that are common to several forms of MD, such as membrane...

Asynchronous Session Types – Exceptions and Multiparty Interactions

DEFF Research Database (Denmark)

Carbone, Marco; Yoshida, Nobuko; Honda, Kohei

2009-01-01

Session types are a formalism for structuring communication based on the notion of session: the structure of a conversation is abstracted as a type which is then used as a basis of validating programs through an associated type discipline. While standard session types have proven to be able to ca...

Research on design of dialogue session concerning nuclear technology

International Nuclear Information System (INIS)

Karikawa, Daisuke; Takahashi, Makoto; Yagi, Ekou; Toba, Tae; Kitamura, Masaharu

2010-01-01

Toward resolving nuclear conflict, deep dialogue sessions among stakeholders having different opinions concerning nuclear technology are strongly required. In order to realize a fair and constructive dialogue session, it is necessary to pay attention to the design of the dialogue session, e.g., participant selection, agenda setting, facilitation, and rules of dialogue. The basic requirements for a dialogue session have been proposed in this study based on theoretical and empirical analyses of previous dialogue sessions on nuclear issues. The theoretical analysis has been performed based on various aspects concerning defects in nuclear communication mentioned in science and technology studies. The empirical analysis has been performed by analyzing participants' responses and by systematizing practical findings of previous dialogues. The proposed requirements for a dialogue session were utilized for the design and operation of a preliminary attempt of a dialogue session named 'Open Forum for Nuclear Communication.' Through the analysis of data, such as minutes and recorded conversations collected after the session, it has been confirmed that the prespecified requirements have been satisfied. In addition, the participants' responses have shown a high acceptance for an open forum. According to these results, the basic validity and effectiveness of the proposed requirements in the design of a dialogue session have been successfully demonstrated. (author)

Enhancing group cognitive-behavioral therapy for hoarding disorder with between-session Internet-based clinician support: A feasibility study.

Science.gov (United States)

Ivanov, Volen Z; Enander, Jesper; Mataix-Cols, David; Serlachius, Eva; Månsson, Kristoffer N T; Andersson, Gerhard; Flygare, Oskar; Tolin, David; Rück, Christian

2018-02-07

Hoarding disorder (HD) is difficult to treat. In an effort to increase efficacy and engagement in cognitive-behavioral therapy (CBT), we developed and evaluated a novel intervention comprising group CBT combined with between-session Internet-based clinician support for people with HD. Twenty participants with HD received group CBT combined with an Internet-support system enabling therapist-participant communication between group sessions. The treatment was associated with a significant reduction on the Saving Inventory-Revised (SI-R) and a large effect size (Cohen's d = 1.57) was found at posttreatment. Treatment gains were maintained at the 3-month follow-up. Group attendance was high and no participants dropped out from treatment prematurely. Between-session motivational support from the therapist was most frequently mentioned as the main strength of the system. The results of this study support adding Internet-based clinician support to group CBT for HD to increase treatment adherence and, potentially, improve the overall efficacy of CBT. © 2018 Wiley Periodicals, Inc.

Intersections and Unions of Session Types

Directory of Open Access Journals (Sweden)

Coşku Acay

2017-02-01

Full Text Available Prior work has extended the deep, logical connection between the linear sequent calculus and session-typed message-passing concurrent computation with equi-recursive types and a natural notion of subtyping. In this paper, we extend this further by intersection and union types in order to express multiple behavioral properties of processes in a single type. We prove session fidelity and absence of deadlock and illustrate the expressive power of our system with some simple examples. We observe that we can represent internal and external choice by intersection and union, respectively, which was previously suggested by Padovani for a different language of session types motivated by operational rather than logical concerns.

Multiparty Session Types as Coherence Proofs

DEFF Research Database (Denmark)

Carbone, Marco; Montesi, Fabrizio; Schürmann, Carsten

2015-01-01

We propose a Curry-Howard correspondence between a language for programming multiparty sessions and a generalisation of Classical Linear Logic (CLL). In this framework, propositions correspond to the local behaviour of a participant in a multiparty session type, proofs to processes, and proof...... normalisation to executing communications. Our key contribution is generalising duality, from CLL, to a new notion of n-ary compatibility, called coherence. Building on coherence as a principle of compositionality, we generalise the cut rule of CLL to a new rule for composing many processes communicating...... in a multiparty session. We prove the soundness of our model by showing the admissibility of our new rule, which entails deadlock-freedom via our correspondence....

Effectiveness of the Electronic Cigarette: An Eight-Week Flemish Study with Six-Month Follow-up on Smoking Reduction, Craving and Experienced Benefits and Complaints

Directory of Open Access Journals (Sweden)

Karolien Adriaens

2014-10-01

Full Text Available Background: Smoking reduction remains a pivotal issue in public health policy, but quit rates obtained with traditional quit-smoking therapies remain disappointingly low. Tobacco Harm Reduction (THR, aiming at less harmful ways of consuming nicotine, may provide a more effective alternative. One promising candidate for THR are electronic cigarettes (e-cigs. The aim of this study was to investigate the efficacy of second-generation e-cigs both in terms of acute craving-reduction in the lab and in terms of smoking reduction and experienced benefits/complaints in an eight-month Randomized Controlled Trial (RCT. Design: RCT with three arms. Methods: Participants (N = 48 unwilling to quit smoking were randomized into two e-cig groups and one control group. During three lab sessions (over two months participants, who had been abstinent for four hours, vaped/smoked for five minutes, after which we monitored the effect on craving and withdrawal symptoms. eCO and saliva cotinine levels were also measured. In between lab sessions, participants in the e-cig groups could use e-cigs or smoke ad libitum, whereas the control group could only smoke. After the lab sessions, the control group also received an e-cig. The RCT included several questionnaires, which repeatedly monitored the effect of ad libitum e-cig use on the use of tobacco cigarettes and the experienced benefits/complaints up to six months after the last lab session. Results: From the first lab session on, e-cig use after four hours of abstinence resulted in a reduction in cigarette craving which was of the same magnitude as when a cigarette was smoked, while eCO was unaffected. After two months, we observed that 34% of the e-cig groups had stopped smoking tobacco cigarettes, versus 0% of the control group (difference p < 0.01. After five months, the e-cig groups demonstrated a total quit-rate of 37%, whereas the control group showed a quit rate of 38% three months after initiating e-cig use. At

Evaluation of a mock interview session on residency interview skills.

Science.gov (United States)

Buckley, Kelsey; Karr, Samantha; Nisly, Sarah A; Kelley, Kristi

2018-04-01

To evaluate the impact of student pharmacist participation in a mock interview session on confidence level and preparation regarding residency interview skills. The study setting was a mock interview session, held in conjunction with student programming at the American College of Clinical Pharmacy (ACCP) Annual Meeting. Prior to the mock interview session, final year student pharmacists seeking residency program placement were asked to complete a pre-session survey assessing confidence level for residency interviews. Each student pharmacist participated in up to three mock interviews. A post-session survey evaluating confidence level was then administered to consenting participants. Following the American Society for Health-System Pharmacists (ASHP) Pharmacy Resident Matching Program (RMP), a post-match electronic survey was sent to study participants to determine their perception of the influence of the mock interview session on achieving successful interactions during residency interviews. A total of 59 student pharmacists participated in the mock interview session and completed the pre-session survey. Participants completing the post-session survey (88%, n = 52) unanimously reported an enhanced confidence in interviewing skills following the session. Thirty responders reported a program match rate of 83%. Approximately 97% (n = 29) of the respondents agreed or strongly agreed that the questions asked during the mock interview session were reflective of questions asked during residency interviews. Lessons learned from this mock interview session can be applied to PGY1 residency mock interview sessions held locally, regionally, and nationally. Students participating in the ACCP Mock Interview Session recognized the importance of the interview component in obtaining a postgraduate year 1 (PGY1) pharmacy residency. Copyright © 2017 Elsevier Inc. All rights reserved.

Environmentally friendly procedure based on VA-MSPD for the determination of booster biocides in fish tissue.

Science.gov (United States)

Vieira, Augusto A; Caldas, Sergiane S; Escarrone, Ana Laura Venquiaruti; Arias, Jean Lucas de Oliveira; Primel, Ednei Gilberto

2018-03-01

Booster biocides have been widely applied to ships and other submerged structures. These compounds can be released into the marine environment as the result of vessel hull leaching and may remain in different environmental compartments. This study aimed at introducing an environmentally friendly procedure for the extraction of irgarol and diuron from fish samples by vortex-assisted matrix solid phase dispersion (VA-MSPD) with detection by liquid chromatography tandem mass spectrometry. Different types of solid supports and solvents were evaluated. The best results were found when 0.5g mussel shell, 0.5g sodium sulfate and 5mL ethanol were used. Analytical recoveries ranged from 81 to 110%, with RSD below 10%, whereas the matrix effect was between -17 and 1% (for all samples under study). LOQ values of irgarol and diuron were 5 and 50ngg -1 , respectively. The method under investigation proved to be a promising alternative to controlling contamination of fish by booster biocides, with low consumption of biodegradable reagents. Copyright © 2017 Elsevier Ltd. All rights reserved.

Evaluation of the criticality constant from Pulsed Neutron Source measurements in the Yalina-Booster subcritical assembly

International Nuclear Information System (INIS)

Bécares, V.; Villamarín, D.; Fernández-Ordóñez, M.; González-Romero, E.M.; Berglöf, C.; Bournos, V.; Fokov, Y.; Mazanik, S.; Serafimovich, I.

2013-01-01

Highlights: ► New methodology proposed to determine the reactivity of subcritical systems. ► Methodology tested in PNS experiments at the Yalina-Booster subcritical assembly. ► The area-ratio and the prompt decay constant methods have been used for validation. ► The absolute reactivity of the system is determined in spite of large spatial effects. - Abstract: The prompt decay constant method and the area-ratio (Sjöstrand) method constitute the reference techniques for measuring the reactivity of a subcritical system using Pulsed Neutron Source experiments (PNS). However, different experiments have shown that in many cases it is necessary to apply corrections to the experimental results in order to take into account spectral and spatial effects. In these cases, the approach usually followed is to develop different specific correction procedures for each method. In this work we discuss the validity of prompt decay constant method and the area-ratio method in the Yalina-Booster subcritical assembly and propose a general correction procedure based on Monte Carlo simulations

Does the Timing of Measurement Alter Session-RPE in Boxers?

Science.gov (United States)

Uchida, Marco C; Teixeira, Luis F M; Godoi, Vladmir J; Marchetti, Paulo H; Conte, Marcelo; Coutts, Aaron J; Bacurau, Reury F P

2014-01-01

The purpose of this study was to compare the influence of measuring the overall session rating of perceived exertion (session-RPE) at 10 vs. 30 minutes following exercise. Eight boxers completed three different standardized training sessions of different intensities (easy, moderate and hard) in a matchedpairs, randomized research design. Exercise intensity was assessed during each bout by measuring heart rate, blood lactate concentration and session-RPE. To assess the effect of measurement timing on session-RPE, RPE data were collected either 10 or 30 minutes post-exercise. There was no significant effect of measurement time on session-RPE values following easy (10 minutes: session-RPE = 1.3 ± 1.0 Arbitrary Unit (AU), %Heart Rate Reserve (HRR) = 49.5 ± 11.1, and ∆Blood lactate = -2.3 ± 16.3%; 30 minutes: session-RPE = 1.7 ± 1.0 AU, %HRR = 51.3 ± 10.8, and ∆Blood lactate = 0.7 ± 25.2%), moderate (10 minutes: session-RPE = 2.7 ± 1.6 AU, %HRR = 67.2 ± 10.8, and ∆Blood lactate = 2.2 ± 19%; 30 minutes: session-RPE = 2.5 ± 0.9 AU, %HRR = 67.2 ± 5.9, and ∆Blood lactate = 24.5 ± 17.1%) and hard (10 minutes: session-RPE = 5.7 ± 1.0 AU, %HRR = 88.1 ± 6.3, and ∆Blood lactate = 146.3 ± 87.9%; 30 minutes: session-RPE = 5.8 ± 1.9 AU, %HRR> = 83.3 ± 8.0, and ∆Blood lactate = 91.6 ± 39%) sessions. In conclusion, our findings suggest that session-RPE can be used in boxing training routines across a range of intensities and accurate measurements can be determined as early as 10 minutes after exercise. Key PointsIt is difficult to quantify and monitoring the external training load in martial arts (e.g. Aikido, Kung Fu, Judo) and physical combat sports (e.g. Boxing, Muay Thai), session RPE method appears to be a reliable method to quantifying training load in those sports.For many athletes it is impractical to wait 30 minutes after training session to provide a session-RPE. The present findings show that collecting ses-sion-RPE measures at 10 min

A comparison of pre-dropout and temporary rupture sessions in psychotherapy.

Science.gov (United States)

Gülüm, I Volkan; Soygüt, Gonca; Safran, Jeremy D

2016-11-15

Although numerous studies have investigated the relationship between the therapeutic alliance and dropout, most have focused on the relationship between alliance quality and psychotherapy outcomes. To compare sessions with therapeutic alliance ruptures and two sessions prior to treatment dropout (pre-dropout) in terms of rupture subtypes, psychotherapists' behavior, attitudes, and session content. We implemented quantitative methods to select the sessions and qualitative methods to analyze them. We analyzed 16 temporary rupture sessions from 12 therapist-patient dyads and 16 pre-dropout sessions from 8 different therapist-patient dyads. The sessions originate from clinical psychology Master's or Doctoral students under supervision in either cognitive behavioral or schema therapy. Pre-dropout sessions were considered unrepaired rupture sessions while rupture sessions were subsequently repaired. Results revealed apparent differences and similarities between the session types in positive and negative psychotherapist behaviors, content intensity, and the type and frequency of ruptures. We explored three new rupture subtypes: attributing positive developments to other sources, indirect speech, and sarcastic hostility. A striking implication is that the frequency of positive and negative psychotherapist behaviors, ruptures, and session content is more likely to decrease in the pre-dropout sessions than in the temporary rupture sessions.

Thermodynamic analysis of transcritical CO2 booster refrigeration systems in supermarket

International Nuclear Information System (INIS)

Ge, Y.T.; Tassou, S.A.

2011-01-01

Research highlights: → The CO 2 booster systems are widely applied in supermarket refrigeration. → Control optimisation can improve the performance of the CO 2 refrigeration systems. → The effects of some important parameters on the system performance are examined. → The optimal high-side pressure in the transcritical cycles is established and derived. -- Abstract: Due to less environmental impact, the CO 2 booster refrigeration system has been widely applied in the modern supermarket as a substitute for the conventional R404A multiplex system. However, the performance efficiency of the CO 2 system still requires further improvement in order to save energy; thus, one of the most efficient techniques would be to investigate and employ the optimal controls for refrigerant high side pressures at various operating states. In this paper, the possible parameters affecting system efficiency of the CO 2 system in the transcritical cycle at a higher ambient air temperature are identified through thermodynamic analysis, but cannot be quantified mathematically because of the high non-linearity involved. Instead, sensitive analysis of the system by means of the thermodynamic model is used to examine the effects of parameters including high side refrigerant pressure, ambient air temperature, refrigerant intermediate pressure, and medium and low evaporating temperatures, superheating, effectiveness of suction line heat exchanger, and compressor efficiency on system performance. Consequently, the optimal high side pressure in the transcritical cycle is established and derived as a function of three important parameters consisting of ambient air temperature, the effectiveness of suction line heat exchanger and compressor efficiency. In addition, optimal operating parameters such as the intermediate pressure are also proposed to improve the system performance.

Booster Applications Facility report, Phase 2

Energy Technology Data Exchange (ETDEWEB)

Thieberger, P. (ed.)

1991-06-01

This report summarizes studies and planning performed by Brookhaven National Laboratory (BNL) personnel at the request of NASA for the design, construction and operation of experimental areas and facilities for utilization of ion beams from the BNL Booster synchrotron particle accelerator. These facilities would be primarily utilized to simulate space radiation for radiobiological research, shielding studies and detector calibrations. The feasibility of such a project has been established, preliminary designs and cost estimates have been developed and a formal proposal can be submitted pending DOE concurrence. The main body of this report consists of the material presented by BNL during the meeting with a NASA appointed Panel on December 10 and 11, 1990. The individual speakers have provided brief summaries of their talks and explanations of their figures. In addition there are two appendices. One, contains detailed discussion of the shared mode of operation and the corresponding beam compatibility tables. The second appendix contains cost estimate details. An executive summary on budgets and schedules has been added, containing possible phased construction and outfitting scenarios and the corresponding expense and commitment profiles as well as new operational cost estimates. Material contained in the executive summary reflects the correction of some errors and new studies performed in response to the NASA Panel suggestions.

Session 2: Availability

CERN Document Server

Uythoven, J

2012-01-01

This session concentrated on the main players affecting the availability of the LHC: the Quench Protection System (QPS), the cryogenics system, the regularly foreseen technical stops and the effect of radiation on equipment failures. A forecast for operation in 2012 was made for all these items.

Cost-effectiveness and cost-utility of cognitive therapy, rational emotive behavioral therapy, and fluoxetine (Prozac) in treating depression: a randomized clinical trial.

Science.gov (United States)

Sava, Florin A; Yates, Brian T; Lupu, Viorel; Szentagotai, Aurora; David, Daniel

2009-01-01

Cost-effectiveness and cost-utility of cognitive therapy (CT), rational emotive behavioral therapy (REBT), and fluoxetine (Prozac) for major depressive disorder (MDD) were compared in a randomized clinical trial with a Romanian sample of 170 clients. Each intervention was offered for 14 weeks, plus three booster sessions. Beck Depression Inventory (BDI) scores were obtained prior to intervention, 7 and 14 weeks following the start of intervention, and 6 months following completion of intervention. CT, REBT, and fluoxetine did not differ significantly in changes in the BDI, depression-free days (DFDs), or Quality-Adjusted Life Years (QALYs). Average BDI scores decreased from 31.1 before treatment to 9.7 six months following completion of treatment. Due to lower costs, both psychotherapies were more cost-effective, and had better cost-utility, than pharmacotherapy: median $26.44/DFD gained/month for CT and $23.77/DFD gained/month for REBT versus $34.93/DFD gained/month for pharmacotherapy, median $/QALYs=$1,638, $1,734, and $2,287 for CT, REBT, and fluoxetine (Prozac), respectively. (c) 2008 Wiley Periodicals, Inc.

Digital intelligent booster for DCC miniature train networks

Science.gov (United States)

Ursu, M. P.; Condruz, D. A.

2017-08-01

Modern miniature trains are now driven by means of the DCC (Digital Command and Control) system, which allows the human operator or a personal computer to launch commands to each individual train or even to control different features of the same train. The digital command station encodes these commands and sends them to the trains by means of electrical pulses via the rails of the railway network. Due to the development of the miniature railway network, it may happen that the power requirement of the increasing number of digital locomotives, carriages and accessories exceeds the nominal output power of the digital command station. This digital intelligent booster relieves the digital command station from powering the entire railway network all by itself, and it automatically handles the multiple powered sections of the network. This electronic device is also able to detect and process short-circuits and overload conditions, without the intervention of the digital command station.

[5-year experience from an anorexia and bulimia clinic. Half of the younger patients recovered after nine months].

Science.gov (United States)

Hjalmers, N; Broberg, A; Nevonen, L

2000-05-31

We present patient data including diagnosis, follow-up and number of sessions. Data for patients 18-25 years of age with anorexia nervosa are also presented. Treatment methods for the various eating disorders are presented. Two projects are presented, one for patients 13-18 years of age and another one for bulimic patients over 18 years. Half of patients 13-18 years of age did not fulfill criteria for an eating disorder at follow-up nine months after the initial session.

Automated design and optimization of flexible booster autopilots via linear programming. Volume 2: User's manual

Science.gov (United States)

Hauser, F. D.; Szollosi, G. D.; Lakin, W. S.

1972-01-01

COEBRA, the Computerized Optimization of Elastic Booster Autopilots, is an autopilot design program. The bulk of the design criteria is presented in the form of minimum allowed gain/phase stability margins. COEBRA has two optimization phases: (1) a phase to maximize stability margins; and (2) a phase to optimize structural bending moment load relief capability in the presence of minimum requirements on gain/phase stability margins.

Psychosocial predator-based animal model of PTSD produces physiological and behavioral sequelae and a traumatic memory four months following stress onset.

Science.gov (United States)

Zoladz, Phillip R; Park, Collin R; Fleshner, Monika; Diamond, David M

2015-08-01

We have a well-established animal model of PTSD composed of predator exposure administered in conjunction with social instability that produces PTSD-like behavioral and physiological abnormalities one month after stress initiation. Here, we assessed whether the PTSD-like effects would persist for at least 4months after the initiation of the psychosocial stress regimen. Adult male Sprague-Dawley rats were exposed to either 2 or 3 predator-based fear conditioning sessions. During each session, rats were placed in a chamber for a 3-min period that terminated with a 30-s tone, followed by 1h of immobilization of the rats during cat exposure (Day 1). All rats in the stress groups received a second fear conditioning session 10days later (Day 11). Half of the stress rats received a third fear conditioning session 3weeks later (Day 32). The two cat-exposed groups were also exposed to daily unstable housing conditions for the entire duration of the psychosocial stress regimen. The control group received stable (conventional) housing conditions and an equivalent amount of chamber exposure on Days 1, 11 and 32, without cat exposure. Behavioral testing commenced for all groups on Day 116. The stress groups demonstrated increased anxiety on the elevated plus maze, impaired object recognition memory and robust contextual and cued fear conditioned memory 3months after the last conditioning session. Combined data from the two stress groups revealed lower post-stress corticosterone levels and greater diastolic blood pressure relative to the control group. These findings indicate that predator-based psychosocial stress produces persistent PTSD-like physiological and behavioral abnormalities that may provide insight into the neurobiological and endocrine sequelae in traumatized people with PTSD. Copyright © 2015 Elsevier Inc. All rights reserved.

MD210 Note: Creation of Hollow Bunches in the PSB

CERN Document Server

Oeftiger, Adrian; Findlay, Alan James; Hancock, Steven; Rumolo, Giovanni; CERN. Geneva. ATS Department

2016-01-01

MD210 aims for the creation of longitudinally hollow bunches in the CERN PS Booster. The first three sessions have been carried out using the radial loop feedback system in order to drive the beam on a dipolar parametric resonance (instead of the phase loop). It has been found that the damping by the phase loop inhibits the excitation of the resonance to a major extent. The hollow distributions generated under these circumstances fail to reach a satisfying bunching factor. Nonetheless, proving the principally successful application of this technique to the PS Booster promises good results once the phase loop system supports trim functions. The approach, actions and detailed results of the first three MD sessions are presented in this paper.

Rf beam loading in the Brookhaven AGS with booster injection

International Nuclear Information System (INIS)

Zhang, S.Y.; Raka, E.; Weng, W.T.

1992-01-01

Multi-batch bunched beam loading during injection from the Booster to the AGS will be discussed. The full intensity beam injection to the upgraded AGS rf system with beam phase and radial feedbacks will be studied. It is shown that a beam phase feedback is necessary in order to guarantee a predictable hewn behavior after the first batch injection, otherwise the initial phase deviation for the following batch injections cannot be controlled. However, the effectiveness of the phase feedback control of the transient beam loading may be limited by an emittance blow up in the process. It is shown that a fast power amplifier feedback with a moderate gain can significantly reduce the transient effect of the bunched beam injection

Optimal scheduling for electric heat booster under day-ahead electricity and heat pricing

DEFF Research Database (Denmark)

Cai, Hanmin; You, Shi; Bindner, Henrik W.

2017-01-01

Multi-energy system (MES) operation calls for active management of flexible resources across energy sectors to improve efficiency and meet challenging environmental targets. Electric heat booster, a solution for Domestic Hot Water (DHW) preparation under Low-Temperature-District-Heating (LTDH......) context, is identified as one of aforementioned flexible resources for electricity and heat sectors. This paper extends the concept of optimal load scheduling under day-ahead pricing from electricity sector only to both electricity and heat sectors. A case study constructing day-ahead energy prices...

Percutaneous Treatment of Simple Hepatic Cysts: The Long-Term Results of PAIR and Catheterization Techniques as Single-Session Procedures

International Nuclear Information System (INIS)

Akhan, Okan; Islim, Filiz; Balci, Sinan; Erbahceci, Aysun; Akpınar, Burcu; Ciftci, Turkmen; Akinci, Devrim

2016-01-01

PurposeThe purpose of our study is to evaluate results of percutaneous aspiration with alcohol sclerotherapy in symptomatic patients with simple hepatic cysts by employing single-session techniques either by a needle or a catheter.Materials and MethodsWe retrospectively included 39 simple hepatic cysts in 35 patients treated via percutaneous aspiration and single-session alcohol sclerotherapy between years 1993 and 2012. Indications were pain (n = 28) or ruling out cystic echinococcus (CE) disease (n = 7). 29 cysts in 26 patients were treated by needle technique (Group A) and ten cysts in nine patients were treated by single-session catheter technique (Group B). Patients were followed for 4–173 months (median: 38 months).ResultsAll patients were successfully treated. Before procedure, cyst volumes were 21–676 cc (median: 94 cc). Post-procedure cyst volumes at last follow-up were 0-40 cc (median: 1 cc). The mean decrease in cyst volume was 95.92 ± 2.86 % in all patients (95.96 ± 3.26 % in Group A and 95.80 ± 6.20 % in Group B). There was no statistically significant difference between the volume reduction rates of Group A and Group B. Only one patient, in Group B, developed a major complication, an abscess. Hospitalization period was 1 day for all patients.ConclusionsFor patients with symptomatic simple hepatic cysts smaller than 500 cc in volume by using puncture, aspiration, injection, and reaspiration (PAIR) technique with only needle, single-session alcohol sclerotherapy of 10 min is a safe and effective procedure with high success rate.

Percutaneous Treatment of Simple Hepatic Cysts: The Long-Term Results of PAIR and Catheterization Techniques as Single-Session Procedures

Energy Technology Data Exchange (ETDEWEB)

Akhan, Okan, E-mail: akhano@tr.net [Hacettepe University Faculty of Medicine, Department of Radiology (Turkey); Islim, Filiz, E-mail: fislim@yahoo.com [Istanbul Bakirkoy Dr. Sadi Konuk Training and Research Hospital, Department of Radiology (Turkey); Balci, Sinan, E-mail: snnbalci@gmail.com [Hacettepe University Faculty of Medicine, Department of Radiology (Turkey); Erbahceci, Aysun, E-mail: aysunerbahceci@yahoo.com [Istanbul Bakirkoy Dr. Sadi Konuk Training and Research Hospital, Department of Radiology (Turkey); Akpınar, Burcu, E-mail: burcu-akpinar@yahoo.com; Ciftci, Turkmen, E-mail: turkmenciftci@yahoo.com; Akinci, Devrim, E-mail: akincid@hotmail.com [Hacettepe University Faculty of Medicine, Department of Radiology (Turkey)

2016-06-15

PurposeThe purpose of our study is to evaluate results of percutaneous aspiration with alcohol sclerotherapy in symptomatic patients with simple hepatic cysts by employing single-session techniques either by a needle or a catheter.Materials and MethodsWe retrospectively included 39 simple hepatic cysts in 35 patients treated via percutaneous aspiration and single-session alcohol sclerotherapy between years 1993 and 2012. Indications were pain (n = 28) or ruling out cystic echinococcus (CE) disease (n = 7). 29 cysts in 26 patients were treated by needle technique (Group A) and ten cysts in nine patients were treated by single-session catheter technique (Group B). Patients were followed for 4–173 months (median: 38 months).ResultsAll patients were successfully treated. Before procedure, cyst volumes were 21–676 cc (median: 94 cc). Post-procedure cyst volumes at last follow-up were 0-40 cc (median: 1 cc). The mean decrease in cyst volume was 95.92 ± 2.86 % in all patients (95.96 ± 3.26 % in Group A and 95.80 ± 6.20 % in Group B). There was no statistically significant difference between the volume reduction rates of Group A and Group B. Only one patient, in Group B, developed a major complication, an abscess. Hospitalization period was 1 day for all patients.ConclusionsFor patients with symptomatic simple hepatic cysts smaller than 500 cc in volume by using puncture, aspiration, injection, and reaspiration (PAIR) technique with only needle, single-session alcohol sclerotherapy of 10 min is a safe and effective procedure with high success rate.

Impact of a single educational session on oral hygiene practices among children of a primary school of Meerut, India

Directory of Open Access Journals (Sweden)

Pawan Parashar

2013-10-01

Full Text Available Oral health promotion through schools is recommended by the World Health Organization (WHO for improving knowledge, attitude, and behavior related to oral health and for prevention and control of dental diseases among school children. In low resource settings, it is important to develop evidence for health education methods in oral health behavioral practices. The objectives of this study were to assess both the baseline awareness and practices regarding oral hygiene and the impact of a single education session on the change in oral health behavior. A school based, cross-sectional study on 112 primary school children was conducted after obtaining the consent of the school authorities and parents. A pretested, structured proforma was used for baseline awareness and behavior regarding oral health. A 30 min educational session was imparted and after 1 month, and the oral health practices were reassessed to find out the impact of the education session. Baseline survey revealed the following findings. Self-reported dental problems were found in 48.22% of the children in the last 6 months. When asked about the risk factors for dental problems, 28.57% mentioned eating sweets followed by improper brushing, whereas 40.17% were not aware about any risk factor for dental problems. It was found that 28.57% of the children did not brush their teeth regularly, whereas 35.71% used a tooth-brush for brushing their teeth. After the intervention, it was observed that there was a significant improvement in the proportion of children using a toothbrush for cleaning their teeth and of those who rinsed their mouth after meals. In conclusion, even a single education session was found to be effective in bringing about a change in the oral health behavior of primary school children.

HIIT in the Real World: Outcomes from a 12-Month Intervention in Overweight Adults.

Science.gov (United States)

Roy, Melyssa; Williams, Sheila M; Brown, Rachel C; Meredith-Jones, Kim A; Osborne, Hamish; Jospe, Michelle; Taylor, Rachael W

2018-04-21

Although high-intensity interval training (HIIT) and moderate-intensity continuous exercise have comparable health outcomes in the laboratory setting, effectiveness studies in real-world environments are lacking. The aim of this study was to determine the effectiveness of an unsupervised HIIT programme in overweight/obese adults over 12 months. 250 overweight/obese adults could choose HIIT or current exercise guidelines of 30 minutes/day moderate-intensity exercise. HIIT participants received a single training session and were advised to independently perform HIIT 3x/week utilizing a variety of protocols. Mixed models, with a random effect for participant, compared differences in weight, body composition, blood pressure, aerobic fitness, physical activity and blood indices at 12 months, adjusting for relevant baseline variables. Forty-two percent (n=104) of eligible participants chose HIIT in preference to current guidelines. At 12 months, there were no differences between exercise groups in weight (adjusted difference HIIT vs conventional; 95% CI: -0.44kg; -2.5, 1.6) or visceral fat (-103cm; -256, 49), although HIIT participants reported greater enjoyment of physical activity (p=0.01). Evidence of adherence to ≥2 sessions/week of unsupervised HIIT (from heart rate monitoring) declined from 60.8% at baseline to 19.6% by 12 months. Participants remaining adherent to HIIT over 12 months (23%) were more likely to be male (67% vs 36%, p=0.03), with greater reductions in weight (-2.7kg; -5.2 -0.2) and visceral fat (-292cm; -483, -101) than non-adherent participants. HIIT was well-accepted by overweight adults and opting for HIIT as an alternative to standard exercise recommendations led to no difference in health outcomes after 12 months. While regular participation in unsupervised HIIT declined rapidly, those apparently adherent to regular HIIT demonstrated beneficial weight loss and visceral fat reduction. Australian New Zealand Clinical Trials Registry (ACTRN

Simulation of space charge effects and transition crossing in the Fermilab Booster

International Nuclear Information System (INIS)

Lucas, P.; MacLachlan, J.

1987-03-01

The longitudinal phase space program ESME, modified for space charge and wall impedance effects, has been used to simulate transition crossing in the Fermilab Booster. The simulations yield results in reasonable quantitative agreement with measured parameters. They further indicate that a transition jump scheme currently under construction will significantly reduce emittance growth, while attempts to alter machine impedance are less obviously beneficial. In addition to presenting results, this paper points out a serious difficulty, related to statistical fluctuations, in the space charge calculation. False indications of emittance growth can appear if care is not taken to minimize this problem

TOPOLOGY FOR A DSP BASED BEAM CONTROL SYSTEM IN THE AGS BOOSTER

International Nuclear Information System (INIS)

DELONG, J.; BRENNAN, J.M.; HAYES, T.; LE, T.N.; SMITH, K.

2003-01-01

The AGS Booster supports beams of ions and protons with a wide range of energies on a pulse-by-pulse modulation basis. This requires an agile beam control system highly integrated with its controls. To implement this system digital techniques in the form of Digital Signal Processors, Direct Digital Synthesizers, digital receivers and high speed Analog to Digital Converters are used. Signals from the beam and cavity pick-ups, as well as measurements of magnetic field strength in the ring dipoles are processed in real time. To facilitate this a multi-processor topology with high bandwidth data links is being designed

Technical assessment of electric heat boosters in low-temperature district heating based on combined heat and power analysis

DEFF Research Database (Denmark)

Cai, Hanmin; You, Shi; Wang, Jiawei

2018-01-01

This paper provides a technical assessment of electric heat boosters (EHBs) in low-energy districts. The analysis is based on a hypothetical district with 23 terraced single-family houses supplied by both a lowtemperature district heating (LTDH) network and a low-voltage network (LVN). Two case...

Effects of a structured 20-session slow-cortical-potential-based neurofeedback program on attentional performance in children and adolescents with attention-deficit hyperactivity disorder: retrospective analysis of an open-label pilot-approach and 6-month follow-up.

Science.gov (United States)

Albrecht, Johanna S; Bubenzer-Busch, Sarah; Gallien, Anne; Knospe, Eva Lotte; Gaber, Tilman J; Zepf, Florian D

2017-01-01

The aim of this approach was to conduct a structured electroencephalography-based neurofeedback training program for children and adolescents with attention-deficit hyperactivity disorder (ADHD) using slow cortical potentials with an intensive first (almost daily sessions) and second phase of training (two sessions per week) and to assess aspects of attentional performance. A total of 24 young patients with ADHD participated in the 20-session training program. During phase I of training (2 weeks, 10 sessions), participants were trained on weekdays. During phase II, neurofeedback training occurred twice per week (5 weeks). The patients' inattention problems were measured at three assessment time points before (pre, T0) and after (post, T1) the training and at a 6-month follow-up (T2); the assessments included neuropsychological tests (Alertness and Divided Attention subtests of the Test for Attentional Performance; Sustained Attention Dots and Shifting Attentional Set subtests of the Amsterdam Neuropsychological Test) and questionnaire data (inattention subscales of the so-called Fremdbeurteilungsbogen für Hyperkinetische Störungen and Child Behavior Checklist/4-18 [CBCL/4-18]). All data were analyzed retrospectively. The mean auditive reaction time in a Divided Attention task decreased significantly from T0 to T1 (medium effect), which was persistent over time and also found for a T0-T2 comparison (larger effects). In the Sustained Attention Dots task, the mean reaction time was reduced from T0-T1 and T1-T2 (small effects), whereas in the Shifting Attentional Set task, patients were able to increase the number of trials from T1-T2 and significantly diminished the number of errors (T1-T2 & T0-T2, large effects). First positive but very small effects and preliminary results regarding different parameters of attentional performance were detected in young individuals with ADHD. The limitations of the obtained preliminary data are the rather small sample size, the

Adolescent abstinence and unprotected sex in CyberSenga, an Internet-based HIV prevention program: randomized clinical trial of efficacy.

Directory of Open Access Journals (Sweden)

Michele L Ybarra

Full Text Available Cost-effective, scalable programs are urgently needed in countries deeply affected by HIV.This parallel-group RCT was conducted in four secondary schools in Mbarara, Uganda. Participants were 12 years and older, reported past-year computer or Internet use, and provided informed caregiver permission and youth assent. The intervention, CyberSenga, was a five-hour online healthy sexuality program. Half of the intervention group was further randomized to receive a booster at four-months post-intervention. The control arm received 'treatment as usual' (i.e., school-delivered sexuality programming. The main outcome measures were: 1 condom use and 2 abstinence in the past three months at six-months' post-intervention. Secondary outcomes were: 1 condom use and 2 abstinence at three-month's post-intervention; and 6-month outcomes by booster exposure. Analyses were intention to treat.All 416 eligible youth were invited to participate, 88% (n = 366 of whom enrolled. Participants were randomized to the intervention (n = 183 or control (n = 183 arm; 91 intervention participants were further randomized to the booster. No statistically significant results were noted among the main outcomes. Among the secondary outcomes: At three-month follow-up, trends suggested that intervention participants (81% were more likely to be abstinent than control participants (74%; p = 0.08, and this was particularly true among youth who were abstinent at baseline (88% vs. 77%; p = 0.02. At six-month follow-up, those in the booster group (80% reported higher rates of abstinence than youth in the intervention, no booster (57% and control (55% groups (p = 0.15; they also reported lower rates of unprotected sex (5% compared to youth in the intervention, no booster (24% and control (21% groups (p = 0.21 among youth sexually active at baseline.The CyberSenga program may affect HIV preventive behavior among abstinent youth in the short term and, with the

Session 7: Reserve

International Nuclear Information System (INIS)

Bailey, R.; Crockford, G.

2001-01-01

The reserve session was devoted to some issues that came up through the workshop, which were grouped into three main areas: The Global Accelerator Network, Problems of stress and how to get organized to minimize them, What should an operations group be responsible for? This paper summarizes the discussions that took place. (author)

Group versus individual sessions delivered by a physiotherapist for female urinary incontinence: an interview study with women attending group sessions nested within a randomised controlled trial

Directory of Open Access Journals (Sweden)

Smith Jan

2009-09-01

Full Text Available Abstract Background The aim was to explore the concerns and expectations of women invited to attend group physiotherapy sessions for the management of female urinary incontinence and whether the experience changed their views; and to gather recommendations from women attending group sessions on the design and delivery of these sessions Methods An interview study nested within a randomised controlled trial in five British NHS physiotherapy departments, including 22 women who had expressed a preference for an individual physiotherapy session but were randomised to, and attended, group sessions. Results Embarrassment was woven throughout women's accounts of experiencing urinary incontinence and seeking health care. Uncertainty about the nature of group sessions was a source of concern. Attending the first session was seen as a big hurdle by many women. However, a sense of relief was common once the session started, with most women describing some benefit from attendance. Recommendations for design and delivery of the sessions from women focused on reducing embarrassment and uncertainty prior to attendance. Conclusion Taking account of women's embarrassment and providing detailed information about the content of group sessions will enable women to benefit from group physiotherapy sessions for the management of female urinary incontinence. Trial Registration Trial registration number: ISRCTN 16772662

An Erlang Implementation of Multiparty Session Actors

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Simon Fowler

2016-08-01

Full Text Available By requiring co-ordination to take place using explicit message passing instead of relying on shared memory, actor-based programming languages have been shown to be effective tools for building reliable and fault-tolerant distributed systems. Although naturally communication-centric, communication patterns in actor-based applications remain informally specified, meaning that errors in communication are detected late, if at all. Multiparty session types are a formalism to describe, at a global level, the interactions between multiple communicating entities. This article describes the implementation of a prototype framework for monitoring Erlang/OTP gen_server applications against multiparty session types, showing how previous work on multiparty session actors can be adapted to a purely actor-based language, and how monitor violations and termination of session participants can be reported in line with the Erlang mantra of "let it fail". Finally, the framework is used to implement two case studies: an adaptation of a freely-available DNS server, and a chat server.

Randomized efficacy trial of early preconception counseling for diabetic teens (READY-girls).