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Sample records for month immediately preceding

  1. Short-term seismic quiescence immediately preceding explosions during the 2011 eruption of Telica Volcano, Nicaragua

    Science.gov (United States)

    Rodgers, M.; Roman, D. C.; Geirsson, H.; La Femina, P. C.; Muñoz, A.; Tenorio, V.

    2013-12-01

    Telica Volcano, Nicaragua, experienced a VEI 2 eruptive episode from March-June 2011. The eruption consisted of numerous small to moderate ash explosions, many of which were observed visually and recorded by a local broadband seismic network (the TESAND network). Seismicity at Telica during both background and eruptive periods is characterized by generally high and variable rates of low-magnitude volcano-seismic events. Explosions at Telica are also detected seismically and distinguished from volcanic earthquakes by the length of the seismic signal, their emergent nature and 'cigar-shaped' envelope, and broadband spectral content. During the month of May 2011, we identified 16 explosion events on a seismometer located 0.5 km from the crater vent, some of which correlate with visually observed explosions. From May 1-12, ten explosions are apparent in continuous seismic data. During this period, the rate of volcano-seismic events is relatively low (0-20 events/hour with an average of 4 events per hour). Prior to eight of the 10 explosions, there were no detected seismic events within one hour of the explosion. From May 13-31, seven explosions were identified in the continuous seismic data. During this period, the rate of volcano-seismic events is relatively high (0-48 events per hour, with an average of 18 events per hour). In the hour preceding all seven explosions, there were no detected volcano-seismic events. Visual inspection of the continuous seismic data confirms that a strong decrease in the number of volcano-seismic events immediately preceded most of the 2011 explosions at Telica Volcano. We suggest that the apparent short-term decrease in seismicity before explosions at Telica is related to a cycle of pressure buildup and release in the shallow magmatic-hydrothermal system, with an increase in pressure prior to the explosions both resulting from and reflecting constriction of gas pathways.

  2. A prospective multi-country observational trial to compare the incidences of diabetic ketoacidosis in the month of Ramadan, the preceding month, and the following month (DKAR international)

    OpenAIRE

    Abdelgadir, Elamin I. E.; Hassanein, Mohamed M.; Bashier, Alaaeldin M. K.; Abdelaziz, Sulaf; Baki, Salwa; Chadli, Asma; Askaoui, Sara; Nawal, El Ansari; Slim, Ines S.; Ghizlane, El Mghari; Hafidh, Khadija; Alawadi, Fatheya

    2016-01-01

    Background 1.7 billion Muslims worldwide obey divine commands of fasting for a month. This may increase the probability of the acute complications of diabetes during the fasting period. Design and methods We primarily aimed to compare the incidences and duration of Diabetic ketoacidosis (DKA) admissions during Ramadan compared to the month before (Shaaban) and the month after (Shawal) as well as the average pre-Ramadan six months' admissions. Our secondary objective was to assess the differen...

  3. The Analysis of two-months effects of muscle stretching. Immediately following injection of methyl prednisolon

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    L. Bidkoli

    2008-01-01

    Full Text Available AbstractBackground and Purpose: Trigger points have been described as causing pain in clinical practice and are a common source of musculoskeletal pain. Trigger point injection can effectively inactivate the trigger points and provide symptomatic relief. Efficacy of injection in the treatment of trigger points depends strongly on the technique of trigger point injection. This study compares muscle stretching immediately after injection of methyl prednisolon vs. injection without stretching in the treatment of trigger points.Materials and Methods: Patients with trigger point pain in the gluteal muscles were recruited using strict inclusion and exclusion criteria from Shiraz Medical School Clinic. Subjects under went two office visits and two phone follow-ups. All patients received injection of lidocaine and methyl prednisolon. In group A, injection was without stretching. In group B, stretching of muscle was done immediately after injection. Evaluation measure tools were 0-10 NRS, VAS and BPI.Results: In respect to VAS, there was a significant statistical difference between both groups one month following injection. In respect to NRS, there was a significant statistical difference between both groups 1 month and 2 months after injection. However, there was no significant statistical difference between both groups in all measurement aspect of BPI, except mood.Conclusion: Muscle stretching immediately after injection was more effective up to two months, than without muscle stretching in the symptomatic treatment of gluteal trigger points.Key words: Trigger points, Stretching, InjectionJ Mazand Univ Med Sci 2008; 18(64: 29-36 (Persian

  4. Long-term history and immediate preceding state affect EEG slow wave characteristics at NREM sleep onset in C57BL/6 mice.

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    Cui, N; Mckillop, L E; Fisher, S P; Oliver, P L; Vyazovskiy, V V

    2014-01-01

    The dynamics of cortical activity across the 24-h day and at vigilance state transitions is regulated by an interaction between global subcortical neuromodulatory influences and local shifts in network synchrony and excitability. To address the role of long-term and immediate preceding history in local and global cortical dynamics, we investigated cortical EEG recorded from both frontal and occipital regions during an undisturbed 24-h recording in mice. As expected, at the beginning of the light period, under physiologically increased sleep pressure, EEG slow waves were more frequent and had higher amplitude and slopes, compared to the rest of the light period. Within discrete NREM sleep episodes, the incidence, amplitude and slopes of individual slow waves increased progressively after episode onset in both derivations by approximately 10-30%. Interestingly, at the beginning of NREM sleep episodes slow waves in the frontal and occipital derivations frequently occurred in isolation, as quantified by longer latencies between consecutive slow waves in the two regions. Notably, slow waves during the initial period of NREM sleep following REM sleep episodes were significantly less frequent, lower in amplitude and exhibited shallower slopes, compared to those that occurred in NREM episodes after prolonged waking. Moreover, the latencies between consecutive frontal and occipital NREM slow waves were substantially longer when they occurred directly after REM sleep compared to following consolidated wakefulness. Overall these data reveal a complex picture, where both time of day and preceding state contribute to the characteristics and dynamics of slow waves within NREM sleep. These findings suggest that NREM sleep initiates in a more "local" fashion when it occurs following REM sleep episodes as opposed to sustained waking bouts. While the mechanisms and functional significance of such a re-setting of brain state after individual REM sleep episodes remains to be

  5. Corrected Hemoglobin A1c as an Index of Glycemic Control in the Preceding One Month

    OpenAIRE

    2002-01-01

    The corrected hemoglobin A1c(cHbA1c) value was calculated on the basis of HbA1c data obtained over 4 months in 19 patients with type 2 diabetes. The usefulness of cHbA1c as a short-term glycemic control index was compared with that of glycated albumin. Both the HbA1c value (measured by immunoassay) and the calculated cHbA1c value showed significant positive correlations with glycated albumin. However, cHbA1c showed a stronger correlation with glycated albumin. In each patient,the variation of...

  6. The Analysis of two-months effects of muscle stretching. Immediately following injection of methyl prednisolon

    OpenAIRE

    L. Bidkoli; A.H. Yazdani; A.R.Moghtaderi; Sh. Mirshams,; M.R. Emad

    2008-01-01

    AbstractBackground and Purpose: Trigger points have been described as causing pain in clinical practice and are a common source of musculoskeletal pain. Trigger point injection can effectively inactivate the trigger points and provide symptomatic relief. Efficacy of injection in the treatment of trigger points depends strongly on the technique of trigger point injection. This study compares muscle stretching immediately after injection of methyl prednisolon vs. injection without stretching in...

  7. Determinants of complementary feeding practices among mothers of 6–24 months failure to thrive children based on behavioral analysis phase of PRECEDE model, Tehran

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    Shams, Nasibeh; Mostafavi, Firoozeh; Hassanzadeh, Akbar

    2016-01-01

    Background: This study intended to clarify the determining factors of complementary feeding practices among Tehran 6–24 months failure to thrive children in order to use the results for planning the interventions to reduce the possible adverse effects. Materials and Methods: In this study, 132 mothers of three medical and health centers were chosen by random sampling among those centers operating under the supervision of south of Tehran District Health Center and study data were collected from them. A valid and reliable questionnaire as a data collection instrument developed based on behavioral analysis phase of PRECEDE model. Spearman and Pearson's correlation coefficient test were used to determine the statistical relationship between factors associated with complementary feeding practices among mothers. Results: The mothers’ knowledge was as follows: 0.8%, 20.4%, and 78.8% of them were good, medium, and poor, respectively. Mean scores for the mothers’ performance in terms of supplementary feeding was 66.8. Pearson correlation indicated a positive and significant correlation between the mothers’ performance with enabling and reinforcing factors, but there wasn’t any significant relationship between the mothers’ performance and knowledge about complementary feeding. Conclusions: According to the obtained results, reinforcing factors, and enabling factors are associated with the mothers’ performance in terms of complementary feeding. Hence, attention to these issues is essential for better health interventions planning. PMID:27500177

  8. Determinants of complementary feeding practices among mothers of 6-24 months failure to thrive children based on behavioral analysis phase of PRECEDE model, Tehran.

    Science.gov (United States)

    Shams, Nasibeh; Mostafavi, Firoozeh; Hassanzadeh, Akbar

    2016-01-01

    This study intended to clarify the determining factors of complementary feeding practices among Tehran 6-24 months failure to thrive children in order to use the results for planning the interventions to reduce the possible adverse effects. In this study, 132 mothers of three medical and health centers were chosen by random sampling among those centers operating under the supervision of south of Tehran District Health Center and study data were collected from them. A valid and reliable questionnaire as a data collection instrument developed based on behavioral analysis phase of PRECEDE model. Spearman and Pearson's correlation coefficient test were used to determine the statistical relationship between factors associated with complementary feeding practices among mothers. The mothers' knowledge was as follows: 0.8%, 20.4%, and 78.8% of them were good, medium, and poor, respectively. Mean scores for the mothers' performance in terms of supplementary feeding was 66.8. Pearson correlation indicated a positive and significant correlation between the mothers' performance with enabling and reinforcing factors, but there wasn't any significant relationship between the mothers' performance and knowledge about complementary feeding. According to the obtained results, reinforcing factors, and enabling factors are associated with the mothers' performance in terms of complementary feeding. Hence, attention to these issues is essential for better health interventions planning.

  9. Modified culotte stenting for treatment of complex coronary bifurcation lesions: immediate and 9-month outcomes in a pilot study

    Institute of Scientific and Technical Information of China (English)

    CHEN Liang-long; FAN Lin; CHEN Zhao-yang; ZHEN Xing-chun; LUO Yu-kun; LIN Chao-gui; PENG Ya-fei

    2011-01-01

    Background The optimal stenting strategy for the treatment of coronary bifurcation lesions (CBLs) remains uncertain. The present study observed technical feasibility and reliability, 9-month clinical and angiographic outcomes of the modified culotte stenting (MCS) in the treatment of CBLs with drug-eluting stents.Methods A total of 34 consecutive patients with CBLs that required stenting the parent vessel (PV), the main branch (MB) and the side branch (SB) were included. All patients were first assigned to receive MCS for CBL interventions (per MCS), and might be switched to receive the double-kissing-crush stenting (DKS) in case of temporally acute branch occlusion (per protocol).Results The immediate angiographic or procedural success was achieved in 33/34 (97%) lesions (patients) per MCS, 34/34 (100%) lesions (patients) per protocol with 100% successful final balloon kissing. The long-term clinical success at 9 months was 94% per MCS and 94% per protocol, only 2 patients had reoccurrence of angina but none of them needed target lesion revascularization. There were no procedure-related biomarker elevation, no in-stent thrombosis peri-procedurally and at 9-month follow-up. Quantitative coronary angiography data at 9 months showed that in-stent (6%) or in-segment (6%) binary stenosis was infrequent, and minimal lumen diameter was significantly reduced but late lumen loss was acceptable with only (0.10±0.14) mm for PV, (0.21 ±0.23) mm for MB and (0.27±0.32) mm for SB.Conclusions MCS for treatment of CBLs that required dual-stent implantation was technically easier and safer, readily to complete final balloon kissing, and was associated with high immediate success and optimal 9-month outcomes.

  10. The Effect of Kangaroo Mother Care Immediately after Delivery on Mother-infant Attachment 3 Months after Delivery

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    Fatemeh Zahra Karimi

    2016-09-01

    Full Text Available Background  The aim of this study was determine the effect of kangaroo mother care (KMC immediately after delivery on mother-infant attachment 3-month after delivery. Materials and Methods: In this RCT study, 72 mother-infant pairs were randomly divided in to kangaroo mother care and routine care groups.The intervention group received kangaroo mother care (KMC in the first two hours post birth. The control group just received routine hospital care. Mothers in the intervention group were encouraged to keep the baby in KMC as much as possible during the day and night throughout the neonatal period. Participants were followed up for three months after birth. The Main outcome measure was mother-infant attachment at 3 months postpartum and maternal anxiety about the baby at the same time. The data was collected by questionnaire (demographic information of parents and neonates and maternal attachment scale. Analysis was performed using SPSS software (version 14. Results: There was no significant difference between two groups regarding their baseline data. Mean maternal attachment score in the KMC group and in the routine care group at three months after delivery was 52.40±3.30 and 49.86±4.18 respectively, which was significantly higher in the KMC group (P

  11. The effect of double-coating and times on the immediate and 6-month dentin bonding of universal adhesives.

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    Pashaev, Diial; Demirci, Mustafa; Tekçe, Neslihan; Tuncer, Safa; Baydemir, Canan

    2017-01-01

    The purpose of this study was to evaluate the effect of double-application coats and times on microtensile bond strength (μTBS) and adhesive-dentin interfaces created by dentin adhesive systems after 6 months of storage in water. Two-hundred sixteen extracted non-carious human third molars were selected for the study. Single-Bond Universal (SU) and All-Bond Universal (AU), Adper Easy One (Eo) Self-Etch adhesive and Adper Single-Bond 2 (Sb) etch-and-rinse adhesive were applied to a flat dentin surface using three methods (1): dentin adhesives were applied as recommended by the manufacturers; (2): two consecutive coats of dentin adhesives were applied before photo-polymerization; and (3): a single coat of adhesive was applied but with twice the manufacturers recommended application time. Microtensile bond strength was determined either immediately or after 6 months of water storage. Data were analyzed using one-way analysis of variance and Tukey's post-hoc tests. At 24 h, groups 1, 2, and 3 exhibited statistically similar results for all dentin adhesive systems. For AU-Er, group 3 showed significantly higher bond strength than all group of AU-Se after 6 months. Universal adhesives seemed more stable against water degradation than traditional two-step etch-and-rinse and all-in-one systems within the 6-month period.

  12. Comparison between Two Techniques Used in Immediate Postplacental Insertion of TCu 380A Intrauterine Device:36-Month follow-up

    Institute of Scientific and Technical Information of China (English)

    徐晋勋; 杨秀兰; 顾兴林; 徐素英; 周晓波; 陈月贞; 肖志琴; 庄留琪

    1999-01-01

    Three hundred and eighty four women in Shanghai who delivered vaginally and chose IUD for contraception received the copper T-380A IUD inserted vaginatty within 10min after delivery of the placenta(i.e.,immediate postplacentat insertion,IPPI).Among them,98.70% were primipara.The women were randomly divided into twogroups:IUD inserted by hand and IUD insreted by ring forceps.Using Life Table Method and X2test,expulsion and other discontinuation rates were compared at 6,12,24,and 36 months post-insertion between these two different groups.No uterine perforation,infection or prolonged period of lochia occurred in the 384 cases.Expulsions were the main reason for discontinuation.From 6 months to 36 months,the gross cumulative rates of all discontinuation events(expulsion, pregnancy,removal for bleed-ing/pain,etc.)were not statistically significantly different(P>0.05).The results suggest that these two different insertion techniques do not significantly affect discontinuation rate in vaginal IPPI using the TCu 380A, which appears to be suitable for postpartum insertion in Chinese women.Other relevant issues,such as breast-feeding and IUD position in uterine cavity,are also analyzed and discussed in this paper.

  13. Bio-Oss collagen in the buccal gap at immediate implants: a 6-month study in the dog.

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    Araújo, Mauricio G; Linder, Elena; Lindhe, Jan

    2011-01-01

    following tooth extraction and immediate implant installation, the edentulous site of the alveolar process undergoes substantial bone modeling and the ridge dimensions are reduced. objective: the objective of the present experiment was to determine whether the process of bone modeling following tooth extraction and immediate implant placement was influenced by the placement of a xenogenic graft in the void that occurred between the implant and the walls of the fresh extraction socket. five beagle dogs about 1 year old were used. The 4th premolar in both quadrants of the mandible ((4) P(4) ) were selected and used as experimental sites. The premolars were hemi-sected and the distal roots removed and, subsequently, implants were inserted in the distal sockets. In one side of the jaw, the marginal buccal-approximal void that consistently occurred between the implant and the socket walls was grafted with Bio-Oss Collagen while no grafting was performed in the contra-lateral sites. After 6 months of healing, biopsies from each experimental site were obtained and prepared for histological analyses. the outline of the marginal hard tissue of the control sites was markedly different from that of the grafted sites. Thus, while the buccal bone crest in the grafted sites was comparatively thick and located at or close to the SLA border, the corresponding crest at the control sites was thinner and located a varying distance below SLA border. it was demonstrated that the placement of Bio-Oss Collagen in the void between the implant and the buccal-approximal bone walls of fresh extraction sockets modified the process of hard tissue healing, provided additional amounts of hard tissue at the entrance of the previous socket and improved the level of marginal bone-to-implant contact.

  14. Addenda to the Preceding Paper

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    Bhatnagar, Rajat; Finn, Robert

    2016-12-01

    This work contains largely afterthoughts, relating to the paper immediately preceding it. We correlate and interpret our contributions in that paper, relative to those of an earlier publication by Aspley, He and McCuan. We propose specific laboratory experiments, suggested by formal predictions of those two papers.

  15. Immediate loading of bimaxillary total fixed prostheses supported by five flapless-placed implants with machined surfaces: A 6-month follow-up prospective single cohort study.

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    Cannizzaro, Gioacchino; Felice, Pietro; Loi, Ignazio; Viola, Paolo; Ferri, Vittorio; Leone, Michele; Collivasone, Dario; Esposito, Marco

    2016-01-01

    To evaluate the clinical outcome of fully edentulous patients rehabilitated with immediately loaded bimaxillary screw-retained metal-resin prostheses supported by five implants placed flapless: two in the mandible and three in the maxillae. Twenty-five consecutively treated patients were recruited. To be immediately loaded, implants had to be inserted with a minimum torque of 80 Ncm. Outcome measures were prosthesis and implant failures, and complications. Six months after loading no patients dropped out and no prosthesis or implant failed. Two maxillary prostheses were loaded early at 8 weeks because implants were inserted with a torque inferior to 45 Ncm. Three complications occurred in two patients but they were all successfully treated. Six months after loading, immediately loaded bimaxillary cross-arch prostheses can be supported by only two mandibular and three maxillary flapless-placed dental implants. Longer follow-ups of approximately 10 years are needed to understand the prognosis of this treatment modality.

  16. Immediate occlusal loading of Tapered Internal Laser-Lok® implants in partial arch rehabilitations: a 24-months clinical and radiographic study

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    M. Grande

    2013-10-01

    Full Text Available Aim The purpose of this 2 year prospective clinical study was to clinically and radiographically evaluate an implant with laser microtextured collar surface placed for immediate loading of fixed prostheses in cases of partial posterior maxillary and/or mandibular edentulism.Materials and methods Thirty-five partially edentulous patients who needed implant treatment and met inclusion criterias were consecutively enrolled at different study-centers in Italy. A total of 107 Tapered Internal Laser-Lok® implants (49 maxillary and 58 mandibular were placed and immediately loaded. All provisional constructions were delivered within 1 hour, and the final constructions placed after 4 months. A total of 107 Tapered Internal Laser-Lok implants (49 maxillary and 58 mandibular were placed and immediately loaded. All provisional restorations were delivered within 1 hour, and the final prosthesis placed after 4 months. A total of 32 prosthetic restorations, consisting of 10 two- units, 12 three-units, and 10 four-units fixed partial dentures were evaluated. Clinical and radiographic outcomes were monitored at follow-up examinations scheduled 6, 12, 24 months after implants placement.Results Five implants were lost after loading (3 implants in a two-unit maxillary restorations, 1 implant in a two-unit mandibular restorations, and 1 implant in three-unit maxillary restorationsgiving a survival rate of 95.4% after 24 months. Mean crestal bone loss at 6, 12, and 24 months after implant insertion was 0.42 +/- 1.1 mm, 0.52 +/- 0.9 mm, and 0.66 +/- 1.3 mm, respectively.Conclusion Although limited bytheshort follow-up, immediate function with Tapered Internal Laser-Lok® implants seems to be a viable option to treat partially edentulous patients.

  17. Nifedipine improves immediate, and 6- and 12-month graft function in cyclosporin A (CyA) treated renal allograft recipients.

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    Harper, S J; Moorhouse, J; Veitch, P S; Horsburgh, T; Walls, J; Bell, P R; Donnelly, P K; Feehally, J

    1992-01-01

    To investigate the effect of oral nifedipine, a calcium channel blocker known not to modify cyclosporin A (CyA) pharmacokinetics, on immediate transplant function and CyA nephrotoxicity, 68 adult renal transplant recipients were pre-operatively randomized to one of three regimes: A (high-dose CyA, initial dose 17 mg/kg per day, maintenance dose 7 mg/kg per day); B (regime A plus oral nifedipine); C low-dose CyA, initial dose 10 mg/kg per day, maintenance 4 mg/kg per day plus azathioprine 1 mg/kg per day). All three groups received identical steroid regimes. Calcium channel blockers of all types were avoided in groups A and C. Delayed graft function (dialysis dependence by day 4) was seen least frequently in group B (P nifedipine significantly improves immediate and medium-term graft function.

  18. Postpartum Hemorrhage Treated with Gelfoam Slurry Embolization Using the Superselective Technique: Immediate Results and 1-Month MRI Follow-up

    Energy Technology Data Exchange (ETDEWEB)

    Pellerin, Olivier, E-mail: olivier.pellerin@egp.aphp.fr [Universite Paris Descartes, Sorbonne Paris Cite, Faculte de Medecine - Assistance Publique-Hopitaux de Paris - Hopital Europeen Georges-Pompidou, Paris, France, Interventional Radiology Department (France); Bats, Anne-Sophie [Universite Paris Descartes, Sorbonne Paris Cite, Faculte de Medecine - Assistance Publique-Hopitaux de Paris - Hopital Europeen Georges-Pompidou, Paris, France, Gynecologic and Oncologic Surgery Department (France); Primio, Massimiliano Di; Palomera-Ricco, Ana [Universite Paris Descartes, Sorbonne Paris Cite, Faculte de Medecine - Assistance Publique-Hopitaux de Paris - Hopital Europeen Georges-Pompidou, Paris, France, Interventional Radiology Department (France); Pinot de Villechenon, Gabrielle [Universite Paris Descartes, Sorbonne Paris Cite, Faculte de Medecine - Assistance Publique-Hopitaux de Paris - Hopital Europeen Georges-Pompidou, Paris, France, Anesthesia and Surgical Intensive Care Unit (France); and others

    2013-02-15

    To evaluate the efficacy and safety of superselective embolization of the uterine arteries in a postpartum hemorrhage. Between November 2004 and January 2011, a total of 44 consecutive women (median {+-} standard deviation age 34 {+-} 3 years, range 23-41 years) were referred to our institution for postpartum intractable hemorrhage management. All patients were embolized with a microcatheter that was placed deep into the uterine arteries upstream of the cervical arteries. The embolic agent was a mixture of contrast medium and 5 Multiplication-Sign 5 Multiplication-Sign 5 cm pieces of gelfoam (Gelita-Spon) modified into a gelatin emulsion as follows: rapid mixing through a three-way stopcock with two 2.5-ml syringes. A 1-ml syringe was used for injection. One month after embolization, all patients underwent magnetic resonance imaging and clinical examination. Technical and clinical success was obtained in all cases. Thirty-five patients experienced bleeding related to poor retraction of the uterus, 7 patients because of a tear of the cervix and 2 because of a vaginal hematoma. Pre- and postembolization red blood cell transfusions were (mean {+-} standard deviation [SD]) 6 {+-} 1.2 (range 3-8) U and 2 {+-} 0.7 (range 2-4) U, respectively. One-month magnetic resonance imaging follow-up revealed no sign of ischemic myometrium or necrosis, and no instances of uterine rupture and no pelvic vein thrombosis. Incidental findings included two small intramyometrial hematic collections. All uterine arteries were patent via magnetic resonance angiography. Seventeen patients had concomitant fibroids, all of which appeared hypovascular. This technique permits good, safe clinical results with no marked damage to the uterine arteries or the uterus itself.

  19. Immediate and longer term impact of the varicella shortage on children 18 and 24 months of age in a community population

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    Zimmerman Rick

    2006-08-01

    Full Text Available Abstract Background Little is known about the impact of the recent varicella vaccine shortage. To assess the temporal trend in varicella vaccine administration before 18 and 24 months of age in a community cohort of children prior to, during and after the recent varicella vaccine shortage. And to compare the temporal trends in varicella vaccinations to trends of an older, more widely accepted vaccine, the MMR. Methods Community population-based birth cohorts were identified who were eligible for the varicella vaccination before, during and after the 2001 to 2002 varicella vaccine shortage. Only children (84% of all who remained in the community through their second birthday were included. For each child in the cohort, the medical records and immunization registry records from both medical facilities in the county were reviewed to identify the dates and sites for all varicella immunizations given. In addition to varicella immunizations, the dates of all MMR vaccinations were recorded. Additional data abstracted included the child's birth date, gender and dates of any recognized cases of chickenpox up through age 24 months. Results Of the 2,512 children in the birth cohorts, 50.8% were boys. In the three cohorts combined, 81.1% of the boys and 79.3% of the girls (p = 0.30 received the varicella vaccine by age 24 months. The pre-shortage community rate of varicella immunization was 79.7% by 24 months of age. During the varicella vaccine shortage, the rate of varicella immunization by 24 months fell to 77.2%. Only 6 additional children received a "catch-up" immunization by 36 months of age. In the post shortage period the community 24-month immunization rate rebounded to a level higher than the pre-shortage rate 84.0%. During the almost three years of observation, the MMR immunization rate by age 24 months was constant (87%. Conclusion The varicella shortage was associated with an immediate drop in the 24-month varicella immunizations rate but

  20. Immediate and longer term impact of the varicella shortage on children 18 and 24 months of age in a community population.

    Science.gov (United States)

    Yawn, Barbara P; Schroeder, Clayton; Wollan, Peter; Rocca, Liliana; Zimmerman, Rick; Bardenheier, Barbara

    2006-08-15

    Little is known about the impact of the recent varicella vaccine shortage. To assess the temporal trend in varicella vaccine administration before 18 and 24 months of age in a community cohort of children prior to, during and after the recent varicella vaccine shortage. And to compare the temporal trends in varicella vaccinations to trends of an older, more widely accepted vaccine, the MMR. Community population-based birth cohorts were identified who were eligible for the varicella vaccination before, during and after the 2001 to 2002 varicella vaccine shortage. Only children (84% of all) who remained in the community through their second birthday were included. For each child in the cohort, the medical records and immunization registry records from both medical facilities in the county were reviewed to identify the dates and sites for all varicella immunizations given. In addition to varicella immunizations, the dates of all MMR vaccinations were recorded. Additional data abstracted included the child's birth date, gender and dates of any recognized cases of chickenpox up through age 24 months. Of the 2,512 children in the birth cohorts, 50.8% were boys. In the three cohorts combined, 81.1% of the boys and 79.3% of the girls (p = 0.30) received the varicella vaccine by age 24 months. The pre-shortage community rate of varicella immunization was 79.7% by 24 months of age. During the varicella vaccine shortage, the rate of varicella immunization by 24 months fell to 77.2%. Only 6 additional children received a "catch-up" immunization by 36 months of age. In the post shortage period the community 24-month immunization rate rebounded to a level higher than the pre-shortage rate 84.0%. During the almost three years of observation, the MMR immunization rate by age 24 months was constant (87%). The varicella shortage was associated with an immediate drop in the 24-month varicella immunizations rate but rebounded quickly to above pre-shortage rates. In this community the

  1. Training paediatric healthcare staff in recognising, understanding and managing conflict with patients and families: findings from a survey on immediate and 6-month impact.

    Science.gov (United States)

    Forbat, Liz; Simons, Jean; Sayer, Charlotte; Davies, Megan; Barclay, Sarah

    2017-03-01

    Conflict is a recognised component of healthcare. Disagreements about treatment protocols, treatment aims and poor communication are recognised warning signs. Conflict management strategies can be used to prevent escalation, but are not a routine component of clinical training. To report the findings from a novel training intervention, aimed at enabling paediatric staff to identify and understand the warning signs of conflict, and to implement conflict resolution strategies. Self-report measures were taken at baseline, immediately after the training and at 6 months. Questionnaires recorded quantitative and qualitative feedback on the experience of training, and the ability to recognise and de-escalate conflict. The training was provided in a tertiary teaching paediatric hospital in England over 18 months, commencing in June 2013. A 4-h training course on identifying, understanding and managing conflict was provided to staff. Baseline data were collected from all 711 staff trained, and 6-month follow-up data were collected for 313 of those staff (44%). The training was successful in equipping staff to recognise and de-escalate conflict. Six months after the training, 57% of respondents had experienced conflict, of whom 91% reported that the training had enabled them to de-escalate the conflict. Learning was retained at 6 months with staff more able than at baseline recognising conflict triggers (Fischer's exact test, p=0.001) and managing conflict situations (Pearson's χ(2) test, p=0.001). This training has the potential to reduce substantially the human and economic costs of conflicts for healthcare providers, healthcare staff, patients and relatives. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/.

  2. Clinical evaluation of a novel dental implant system as single implants under immediate loading conditions - 4-month post-loading results from a multicentre randomised controlled trial.

    Science.gov (United States)

    Esposito, Marco; Trullenque-Eriksson, Anna; Blasone, Rodolfo; Malaguti, Giuliano; Gaffuri, Cristiano; Caneva, Marco; Minciarelli, Armando; Luongo, Giuseppe

    To evaluate the safety and clinical effectiveness of a novel dental implant system (GENESIS Implant System, Keystone Dental, Massachusetts, USA) using another dental implant system by the same manufacturer as a control (PRIMA Implant System, Keystone Dental). A total of 53 patients requiring at least two single crowns had their sites randomised according to a split-mouth design to receive both implant systems at six centres. If implants could be placed with a torque superior to 40 Ncm they were to be loaded immediately with provisional crowns, otherwise after 3 months of submerged healing. Provisional crowns were replaced by definitive crowns 4 months after initial loading, when the follow-up period for the initial part of this study was completed. Outcome measures were crown/implant failures, complications, pink esthetic score (PES), peri-implant marginal bone level changes, plaque score, marginal bleeding, patients and preference of the clinician. In total 53 PRIMA and 53 GENESIS implants were placed. Three patients dropped out but all of the remaining patients were followed up to 4-months post-loading. No PRIMA implant failed whereas four GENESIS implants failed. Only two complications were reported for PRIMA implants. There were no statistically significant differences for crown/implant failures (difference in proportions = 0.080; P (McNemar test) = 0.125) and complications (difference in proportions = -0.04; P (McNemar test) = 0.500) between the implant systems. There were no differences at 4-months post-loading for plaque (difference = -0.54, 95% CI: -3.01 to 1.93; P (Paired t-test) = 0.660), marginal bleeding (difference = -3.8, 95% CI: -7.63 to 0.019; P (Paired t-test) = 0.051), PES (difference = 0.47, 95% CI: -0.56 to 1.50; P (Paired t-test) = 0.365) and marginal bone level changes (difference in mm = -0.04, 95% CI: -0.33 to 0.26; P (Paired t-test) = 0.795). The majority of the patients (46) had no

  3. Optical Flashes Preceding GRBs

    CERN Document Server

    Paczynski, B

    2001-01-01

    Only one optical flash associated with a gamma-ray burst has been detected so far by ROTSE. There are also upper limits obtained by several groups for several bursts. Recent model calculations indicate a possibility that optical flash may precede the GRB. Such flashes are undetectable in the currently popular observing mode, with optical instruments responding to GRB triggers. There is a need to develop all sky optical monitoring system capable of recognizing flashes in real time, and more powerful instruments that could respond robotically to optical triggers and carry out follow up observations.

  4. Six months later: Testing the Coulomb stress change model by examining calculations made immediately after the 12 May, 2008 Ms=8.0 Wenchuan earthquake

    Science.gov (United States)

    Parsons, T.; Ji, C.; Kirby, E.

    2008-12-01

    On the 12th of May, 2008 a devastating Ms=8.0 earthquake struck the eastern edge of the Tibetan Plateau, collapsing buildings and killing thousands in major cities aligned along the western Sichuan basin in China. After a high-magnitude earthquake like the 12 May event, rearrangement of stresses in the crust commonly causes subsequent damaging earthquakes. The Sichuan basin and surroundings are crossed by major active strike-slip and thrust faults. By 72 hours after the earthquake, coseismic stress changes were calculated on models of those faults, with many showing significant stress increases. Rapid mapping of stress changes was intended to locate fault sections with relatively higher odds of producing the largest aftershocks and to enable prospective testing of the static-stress triggering hypothesis. A recent prospective test of the method was conducted by McCloskey et al. [2005] after the great 2004 Sumatra earthquake, and was validated by a M=8.7 shock that struck three months later in a region calculated to have been stressed by the mainshock. Our test begins at the time peer review was completed, 38 days after the mainshock on 19 June, 2008. Thus aftershocks occurring between that time and the present can be used for prospective testing. As of this writing, in our test region magnitude greater than 4.0 aftershocks have been largely confined to the mainshock rupture zone, with virtually no activity on Sichuan basin faults with calculated stress increases. Examination of magnitude-frequency behavior of the aftershocks suggests either a corner magnitude at about magnitude 6, or a deficiency in the magnitude greater than 6 range. This experiment is ongoing, and time will tell if the Coulomb model is confirmed in the Sichuan region; our conclusion at present is that there has been no validation, and that use of a generalized aftershock forecast model would have been sufficient.

  5. Metabolomic change precedes apple superficial scald symptoms.

    Science.gov (United States)

    Rudell, David R; Mattheis, James P; Hertog, Maarten L A T M

    2009-09-23

    Untargeted metabolic profiling was employed to characterize metabolomic changes associated with 'Granny Smith' apple superficial scald development following 1-MCP or DPA treatment. Partial least-squares discriminant analyses were used to link metabolites with scald, postharvest treatments, and storage duration. Models revealed metabolomic differentiation between untreated controls and fruit treated with DPA or 1-MCP within 1 week following storage initiation. Metabolic divergence between controls and DPA-treated fruit after 4 weeks of storage preceded scald symptom development by 2 months. alpha-Farnesene oxidation products with known associations to scald, including conjugated trienols, 6-methyl-5-hepten-2-one, and 6-methyl-5-hepten-2-ol, were associated with presymptomatic as well as scalded control fruit. Likewise, a large group of putative triterpenoids with mass spectral features similar to those of ursolic acid and beta-sitosterol were associated with control fruit and scald. Results demonstrate that extensive metabolomic changes associated with scald precede actual symptom development.

  6. Cimentos endodônticos - selamento marginal apical imediato e após armazenamento de seis meses Endodontic cements - immediate apical sealing and after a six-month storage

    Directory of Open Access Journals (Sweden)

    Marcia Carneiro VALERA

    1998-10-01

    Full Text Available Este trabalho avaliou o selamento marginal apical de canais radiculares obturados com os cimentos endodônticos Sealapex, Apexit, Sealer 26 e Ketac Endo. Utilizaram-se 136 raízes, cujos canais radiculares, após o preparo biomecânico, foram obturados pela técnica da condensação lateral ativa com os cimentos em estudo. Metade das amostras, imediatamente após as obturações, foram imersas na solução de azul de metileno a 2% e a outra metade após 6 meses de armazenamento em plasma sangüíneo humano. Observou-se que os cimentos Sealapex e Sealer 26 apresentaram infiltrações médias estatisticamente iguais entre si e menores que as observadas para os demais cimentos (p The aim of this study was to verify the apical sealing of root canals obturated with Sealapex, Apexit, Sealer 26, and Ketac Endo cements. A hundred and thirty six dental roots were used for the experiment. After biomechanical preparation and lateral condensation filling, half of the roots were placed in human blood plasma storage medium for 6 months. The remaining samples were immediately placed in methylene blue, under a temporary vacuum, and after one week the amount of dye penetration measured. The stored samples were similarly treated after the 6-month storage period. Statistical analysis of the results revealed that the groups obturated with Sealapex and Sealer 26 showed the smallest amount of apical leakage (p < 0.05. There were significant differences in the amount of dye penetration after 6 months of storage (1.275 mm, when compared to the results found without storage (0.829 mm (p < 0.05.

  7. PRECEDENCE AS A PSYCHOLINGUISTIC CATEGORY

    Directory of Open Access Journals (Sweden)

    Panarina Nadezhda Sergeevna

    2015-06-01

    Full Text Available The use of particular linguistic units by representatives of a linguacultural community as the most preferable verbal actions is not necessary to be a case of verbal operations with some culturally specific knowledge. The analysis of a psychosocial mechanism used for generation and verbalization of such a knowledge allows to define the nature of precedence as a characteristic of meaning that is being effected in a speech act. The development of precedent meaning indispensably assumes not only generation of the definition component, but also entry into a structure of a culturological component meaning. The culturological component reflects a relationship between a subject-concept component of the meaning and the other elements of a speech situation – the relationship, which is notional for a person. Importance of the relationship consists in fact that definition of its content represents to a person their social identity. Until a person understands the content of relationship, which is represented by the culturological component, the use of corresponding linguistic units to nominate new objects of reality is a supraliminal appeal to the precedent knowledge, a speech act. But for new acts of usage the main thing is definitely quality of relationship as a characteristic of the cultural group stability, and the linguistic unit usage derives a new function. When the culturological component of the meaning is not included into generalization, since it is irrelevant one, and the core of meaning is composed of new and more relevant for the usage features, you can no more realize the inner form of the precedent meaning. The outer form is still relevant, since it is kept in mind by the representatives of linguaculture as the one which is preferable for usage. In this case the linguistic unit is just a tool not related to verbal representation of socially significant attitude, and its usage is a speech operation, a way to perform different speech acts

  8. The influence of behavior preceding a reinforced response on behavior change in the classroom.

    Science.gov (United States)

    Kazdin, A E

    1977-01-01

    The influence of behavior that immediately precedes a reinforced target response on the effectiveness of a reinforcement contingency was examined in two experiments with mentally retarded children in a special-education classroom. Two reinforcement schedules were examined in each experiment. For each schedule, a prespecified period of attentive behavior served as the target response. The schedules differed in whether inattentive or attentive behavior was required immediately to precede the target response. These schedules were examined with one child in a simultaneous treatment design using praise as the reinforcer (Experiment I), and with two children in separate reversal designs using tokens as the reinforcer (Experiment II). While attentive behavior increased under each schedule, the increase was greater when attentive rather than inattentive behavior preceded the reinforced response. The results indicated that the effect of a contingency may be determined not only by the specific response reinforced but also by the behavior that immediately precedes that response.

  9. [Psychosocial stress preceding drug-related deaths].

    Science.gov (United States)

    Kraus, L; Müller-Kalthoff, T

    2002-10-01

    This article analyses drug-related deaths in the German Federal States of Bavaria (Munich, Nuremberg and Augsburg counties) during 1999 and Baden-Wurttemberg (Stuttgart and Mannheim counties) during 1999 and in the first half of 2000. The persons who had been in contact with drug care services were studied for psychosocial stress preceding drug-related deaths. Epidemiological data from different sources (police, relatives, counselling centres, detoxification clinics, therapy and substitution treatment) were collated to estimate factors of psychosocial stress preceding drug deaths. The results in both Laender indicate high prevalence rates of a history of at least one non-fatal overdose (approx. 50%) or a suicide attempt (approx. 35%). More than 40% of the deceased had been suffering from at least one additional mental disorder, in most cases from depression. At least one critical life event (in most cases, a relapse) or a period of abstinence (i.e., due to imprisonment, therapy or detoxification) during the past three months before death was reported for more than half of the addicts. The results were discussed in the light of data on opiate users and the general population. Improved specialist training of therapeutic and medical workers as well as of any other co-operating professionals is considered a necessary prerequisite for an early detection of risk factors.

  10. Weak Precedence Story Parsing Grammar

    Institute of Scientific and Technical Information of China (English)

    张松懋

    1995-01-01

    Story understanding is one of the important branches of natural language understanding research in AI techniques.The story understanding approach based on Story Parsing Grammar (SPG) involves that SPG is used to represent different abstracting processes of stories with different levels in story understanding and that the story understanding process is converted to the recognition process of stories using the syntactic parser of SPG.This kind of story understanding is called story parsing.In this paper,firstly a subclass of SPG,called Weak Precedence SPG(WPSPG),is defined.Afterwards the syntactic parsing algorithm of WPSPG is studied.An example of story parsing is also given.

  11. [Clinical and economical comparison between in-house (Make) and outsourcing (Buy) management of the cardiac catheterization laboratory from two high-volume diagnostic and interventional centers: immediate and 6-month results].

    Science.gov (United States)

    Varbella, Ferdinando; Minniti, Davide; Belli, Riccardo; Gualano, Maria Rosaria; Tomassini, Francesco; Gagnor, Andrea; Gambino, Alfonso; Tizzani, Emanuele; Montali, Nicolò; Ceruti, Michele; Gianino, Maria Michela

    2014-04-01

    Percutaneous coronary interventions (PCI) are widespread procedures in the Italian Healthcare System, but concerns are raised about their economic sustainability. In the last decade, public hospitals have outsourced the PCI services (building and maintaining the technological instruments and the personnel) "buying" them from private companies (Buy) rather than building and maintaining them through public expenditure (Make). The aim of this study was to compare the economic and clinical impact of these two management solutions (Buy and Make) in two community hospitals located in the Turin metropolitan area (Italy). We conducted: 1) a quantitative assessment in order to compare differences in the economic impact between Buy and Make for providing PCI; 2) a qualitative assessment comparing the clinical characteristics of two inpatient populations undergoing PCI and then analyzing the efficacy of the procedure in-hospital and at 6-month follow-up. Between January and June 2010, a total of 332 patients underwent PCI at the "degli Infermi" Hospital in Rivoli and 340 at the "Maria Vittoria" Hospital in Turin (Italy). There were no significant differences between the two populations neither about the clinical characteristics nor in procedural efficacy (either immediate or at follow-up). For 600 units of diagnostic-therapeutic pathway, the net present value at a discount rate of 3.5% of the Make project is higher than that of the Buy by €278.402,25, and is therefore the less convenient of the two solutions. The Buy solution is still the more convenient of the two at volumes <700 units. Our findings show that the Buy solution, if tailored to the specific local needs, provides access to sophisticated technology without making worse quality of services and may save capital expenditure below 700 PCI/years.

  12. Respiratory infections precede adult-onset asthma.

    Directory of Open Access Journals (Sweden)

    Aino Rantala

    Full Text Available BACKGROUND: Respiratory infections in early life are associated with an increased risk of developing asthma but there is little evidence on the role of infections for onset of asthma in adults. The objective of this study was to assess the relation of the occurrence of respiratory infections in the past 12 months to adult-onset asthma in a population-based incident case-control study of adults 21-63 years of age. METHODS/PRINCIPAL FINDINGS: We recruited all new clinically diagnosed cases of asthma (n = 521 during a 2.5-year study period and randomly selected controls (n = 932 in a geographically defined area in South Finland. Information on respiratory infections was collected by a self-administered questionnaire. The diagnosis of asthma was based on symptoms and reversible airflow obstruction in lung function measurements. The risk of asthma onset was strongly increased in subjects who had experienced in the preceding 12 months lower respiratory tract infections (including acute bronchitis and pneumonia with an adjusted odds ratio (OR 7.18 (95% confidence interval [CI] 5.16-9.99, or upper respiratory tract infections (including common cold, sinusitis, tonsillitis, and otitis media with an adjusted OR 2.26 (95% CI 1.72-2.97. Individuals with personal atopy and/or parental atopy were more susceptible to the effects of respiratory infections on asthma onset than non-atopic persons. CONCLUSIONS/SIGNIFICANCE: This study provides new evidence that recently experienced respiratory infections are a strong determinant for adult-onset asthma. Reducing such infections might prevent onset of asthma in adulthood, especially in individuals with atopy or hereditary propensity to it.

  13. INTEGRATED APPROACH TO GENERATION OF PRECEDENCE RELATIONS AND PRECEDENCE GRAPHS FOR ASSEMBLY SEQUENCE PLANNING

    Institute of Scientific and Technical Information of China (English)

    2002-01-01

    An integrated approach to generation of precedence relations and precedence graphs for assembly sequence planning is presented, which contains more assembly flexibility. The approach involves two stages. Based on the assembly model, the components in the assembly can be divided into partially constrained components and completely constrained components in the first stage, and then geometric precedence relation for every component is generated automatically. According to the result of the first stage, the second stage determines and constructs all precedence graphs. The algorithms of these two stages proposed are verified by two assembly examples.

  14. Optimal Solutions for the Temporal Precedence Problem

    DEFF Research Database (Denmark)

    Brodal, Gerth Stølting; Makris, Christos; Sioutas, Spyros;

    2002-01-01

    a in the structure, while the operation precedes (a,b) returns true iff element a was inserted before element b temporally. In [11] a solution was provided to the problem with worst-case time complexity O (log log n ) per operation and O(n log log n) space, where n is the number of elements inserted. It was also...... demonstrated that the precedes operation has a lower bound of Ω (log log n ) for the Pure Pointer Machine model of computation. In this paper we present two simple solutions with linear space and worst-case constant insertion time. In addition, we describe two algorithms that can handle the precedes (a...

  15. Effectiveness of the PRECEDE model in obese patients undergoing primary care nurses follow-up

    Directory of Open Access Journals (Sweden)

    Inés Maria Barrio Cantalejo

    2004-04-01

    Full Text Available Obesity is a serious problem in western modern countries. Primary care nurses has to follow up these patients but often with poor results. The PRECEDE model (Green L.W try to help patients to identify factors that predispose, make easier or reinforce their relationship with food and physical exercise. Objectives: To evaluate if PRECEDE makes easier the adherence of obese patients to a new style of feeding and exercise that reduces their BMI. Metodology: Experimental design, community randomised study. We analysed two samples of two different interventions: in one we applied the PRECEDE, in the other one the conventional advice about diet and exercise. Measures at 12 and 18 months. Both samples were homogeneous. The relationship between qualitative data has been studied through the Pearson x2 test and the comparison of quantitative data between two groups through the Student T test for independent samples. Results: a The PRECEDE intervention group lost more weigh than control at 12ª month, but this difference is almost null at 18º month. b The BMI difference has low clinical value because in both cases the final BMI is >30. Conclusions: a PRECEDE model shows a major capacity to reduce the BMI than the conventional model at short time. b To conclude that the PRECEDE weigh reduction is clinically effective we should have to extend our educational intervention longer time.

  16. Arterial stiffening precedes systolic hypertension in diet-induced obesity.

    Science.gov (United States)

    Weisbrod, Robert M; Shiang, Tina; Al Sayah, Leona; Fry, Jessica L; Bajpai, Saumendra; Reinhart-King, Cynthia A; Lob, Heinrich E; Santhanam, Lakshmi; Mitchell, Gary; Cohen, Richard A; Seta, Francesca

    2013-12-01

    Stiffening of conduit arteries is a risk factor for cardiovascular morbidity. Aortic wall stiffening increases pulsatile hemodynamic forces that are detrimental to the microcirculation in highly perfused organs, such as the heart, brain, and kidney. Arterial stiffness is associated with hypertension but presumed to be due to an adaptive response to increased hemodynamic load. In contrast, a recent clinical study found that stiffness precedes and may contribute to the development of hypertension although the mechanisms underlying hypertension are unknown. Here, we report that in a diet-induced model of obesity, arterial stiffness, measured in vivo, develops within 1 month of the initiation of the diet and precedes the development of hypertension by 5 months. Diet-induced obese mice recapitulate the metabolic syndrome and are characterized by inflammation in visceral fat and aorta. Normalization of the metabolic state by weight loss resulted in return of arterial stiffness and blood pressure to normal. Our findings support the hypothesis that arterial stiffness is a cause rather than a consequence of hypertension.

  17. Learning New Principles from Precedents and Exercises.

    Science.gov (United States)

    1981-05-01

    number of corresponding things, for some Shakespeare comparisons are as follows: Patrick H. Winston - 34- Notes HA HA JU OT TA MAcbeth 199 HAmlet 110...constitute the competence to be understood. Let us begin, then, by specifying some tasks to be performed. Consider the following precis of Macbeth ...given by a teacher as a precedent: In MA there is Macbeth Lady- Macbeth Duncan and Macduff. Macbeth is an evil noble. Lady- Macbeth is a greedy ambitious

  18. Nontransitivity of sperm precedence in Drosophila.

    Science.gov (United States)

    Clark, A G; Dermitzakis, E T; Civetta, A

    2000-06-01

    Sperm competition is an important component of fitness in Drosophila, but we still do not have a clear understanding of the unit of selection that is relevant to sperm competition. Here we demonstrate that sperm competitive ability is not a property of the sperm haplotype, but rather of the diploid male's genotype. Then we test whether the relative sperm competitive ability of males can be ranked on a linear array or whether competitive ability instead depends on particular pairwise contests among males. Sperm precedence of six chromosome-extracted lines was tested against three different visible marker lines (cn bw, bwD, and Cy), and the rank order of the six lines differed markedly among the mutant lines. Population genetic theory has shown that departures from transitivity of sperm precedence may be important to the maintenance of polymorphism for genes that influence sperm competitive ability. The nontransitivity seen in sperm precedence should theoretically increase the opportunity for polymorphism in genes that influence this phenotype.

  19. APOE polymorphisms influence longitudinal lipid trends preceding intracerebral hemorrhage

    Science.gov (United States)

    Phuah, Chia-Ling; Raffeld, Miriam R.; Ayres, Alison M.; Gurol, M. Edip; Viswanathan, Anand; Greenberg, Steven M.; Biffi, Alessandro; Rosand, Jonathan

    2016-01-01

    Objective: We sought to determine whether APOE genotype influences a previously observed decline in serum total cholesterol (TC) and low-density lipoprotein (LDL) levels preceding primary intracerebral hemorrhage (ICH), as a potential demonstration of nonamyloid mechanisms of APOE in ICH risk. Methods: We performed a single-center retrospective longitudinal analysis using patients with known APOE genotype drawn from an ongoing cohort study of ICH. Serum lipid measurements for TC, triglycerides (TGs), LDL, and high-density lipoprotein (HDL) collected within 2 years before and after index ICH were extracted from electronic medical records. Piecewise linear mixed-effects models were used to compare APOE allele–specific effects on temporal serum lipid trends in ICH. Demographics, medical history, medications, and health maintenance data were included as fixed effects. Inter- and intraindividual variations in lipid levels were modeled as random effects. Results: A total of 124 ICH cases were analyzed. APOE ε4 carriers had greater rates of decline in serum TC and LDL within 6 months preceding ICH (TC: −7.30 mg/dL/mo, p = 0.0035; LDL: −8.44 mg/dL/mo, p = 0.0001). Conversely, serum TC and LDL levels in APOE ε2 carriers were unchanged within the same time period. APOE genotype had no associations with serum HDL or TG trends. Conclusions: APOE allele status predicts serum TC and LDL changes preceding acute ICH. Our results have implications for ongoing efforts in dissecting the role of dyslipidemia in cerebrovascular disease risk. APOE genotype–specific influence on lipid trends provides a clue for one mechanism by which APOE may influence risk of ICH. Further characterization of the metabolic roles of APOE is needed to improve the understanding of APOE biology in cerebrovascular disease risk. PMID:27433544

  20. Different Fear-Regulation Behaviors in Toddlerhood: Relations to Preceding Infant Negative Emotionality, Maternal Depression, and Sensitivity

    Science.gov (United States)

    Gloggler, Bettina; Pauli-Pott, Ursula

    2008-01-01

    In the study presented, the development of different fear regulation behaviors and their associations with preceding maternal sensitivity and depression is addressed. A sample of 64 mother-child pairs was examined at the children's ages of 4, 12, and 30 months. Four-month negative reactivity and 12- and 30- month behavioral inhibition and fear…

  1. Immediate hypersensitivity to chlorhexidine.

    Science.gov (United States)

    Vu, Mi; Rajgopal Bala, Harini; Cahill, Jennifer; Toholka, Ryan; Nixon, Rosemary

    2017-06-07

    Chlorhexidine is a widely used and effective antiseptic agent. Although skin contact is usually well tolerated, it may cause both immediate and delayed hypersensitivity reactions. We report a case of immediate hypersensitivity to chlorhexidine causing both skin and respiratory symptoms following occupational exposure to chlorhexidine in a health-care worker. © 2017 The Australasian College of Dermatologists.

  2. Hydroclimatic conditions preceding the March 2014 Oso landslide

    Science.gov (United States)

    Henn, Brian; Cao, Qian; Lettenmaier, Dennis P.; Magirl, Christopher S.; Mass, Clifford; Bower, J. Brent; St. Laurent, Michael; Mao, Yixin; Perica, Sanja

    2015-01-01

    The 22 March 2014 Oso landslide was one of the deadliest in U.S. history, resulting in 43 fatalities and the destruction of more than 40 structures. We examine synoptic conditions, precipitation records and soil moisture reconstructions in the days, months, and years preceding the landslide. Atmospheric reanalysis shows a period of enhanced moisture transport to the Pacific Northwest beginning on 11 February 2014. The 21- to 42-day periods prior to the landslide had anomalously high precipitation; we estimate that 300-400 mm of precipitation fell at Oso in the 21 days prior to the landslide. Relative only to historical periods ending on 22 March, the return periods of these precipitation accumulations are large (25-88 years). However, relative to the largest accumulations from any time of the year (annual maxima), return periods are more modest (2-6 years). In addition to the 21-42 days prior to the landslide, there is a secondary maximum in the precipitation return periods for the 4 years preceding the landslide. Reconstructed soil moisture was anomalously high prior to the landslide, with a return period that exceeded 40 years about a week before the event.

  3. Immediate loading of immediate mandibular implants with a full-arch fixed prosthesis: a preliminary study.

    Science.gov (United States)

    Peñarrocha, Miguel; Boronat, Araceli; Garcia, Berta

    2009-06-01

    To determine the survival of immediate dental implants with immediate loading in the partially edentulous mandible, by use of a full-arch screw-retained provisional restoration. Patients who were partially edentulous in the mandible with indications for extraction of the remaining teeth and with a minimum follow-up of 12 months after implant placement were included in the study. They were treated in chronologic order by the insertion of 6 Defcon dental implants (Impladent, Sentmenat, Spain) subjected to immediate loading (4 interforaminal and 2 posterior placements). Implants with a minimum primary stability of 60 implant stability quotient were loaded. All resin screw-retained prostheses were inserted and loaded with fully functional occlusion within 24 hours of implant placement. Eleven patients were treated with immediate implants, although 2 patients were excluded from the study for having an implant stability quotient value below 60 in at least one of the implants after surgery and did not undergo restoration with immediate loading. Fifty-four implants were placed in 9 partially edentulous patients with immediate loading with a full-arch screw-fixed prosthesis. The patients wore this provisional prosthesis during the healing period (2 months) without complication and with a high level of comfort. The survival rate of the implants was 100% at 12 months of follow-up. Immediate mandibular loading with immediate full-arch implant-supported and screw-retained restorations is a viable treatment alternative, yielding a 100% success rate in this small series of patients.

  4. Monthly errors

    Data.gov (United States)

    U.S. Environmental Protection Agency — The 2006 monthly average statistical metrics for 2m Q (g kg-1) domain-wide for the base and MODIS WRF simulations against MADIS observations. This dataset is...

  5. Response inhibition and immediate arousal in children with high-functioning autism

    NARCIS (Netherlands)

    Raymaekers, Ruth; van der Meere, Jaap; Roeyers, Herbert

    2006-01-01

    The current study compared high-functioning children with autism (HFA) and a peer control group on an immediate arousal task measuring response inhibition. In one condition go stimuli were presented whereas in another condition a tone preceded the go stimulus. The tone caused an immediate arousal ef

  6. [Wide QRS tachycardia preceded by pacemaker spikes].

    Science.gov (United States)

    Romero, M; Aranda, A; Gómez, F J; Jurado, A

    2014-04-01

    The differential diagnosis and therapeutic management of wide QRS tachycardia preceded by pacemaker spike is presented. The pacemaker-mediated tachycardia, tachycardia fibrillo-flutter in patients with pacemakers, and runaway pacemakers, have a similar surface electrocardiogram, but respond to different therapeutic measures. The tachycardia response to the application of a magnet over the pacemaker could help in the differential diagnosis, and in some cases will be therapeutic, as in the case of a tachycardia-mediated pacemaker. Although these conditions are diagnosed and treated in hospitals with catheterization laboratories using the application programmer over the pacemaker, patients presenting in primary care clinic and emergency forced us to make a diagnosis and treat the haemodynamically unstable patient prior to referral. Copyright © 2012 Sociedad Española de Médicos de Atención Primaria (SEMERGEN). Publicado por Elsevier España. All rights reserved.

  7. Cochlear contributions to the precedence effect.

    Science.gov (United States)

    Verhulst, Sarah; Bianchi, Federica; Dau, Torsten

    2013-01-01

    Normal-hearing individuals have sharply tuned auditory filters, and consequently their basilar-membrane (BM) impulse responses (IRs) have durations of several ms at frequencies in the range from 0 to 5 kHz. When presenting clicks that are several ms apart, the BM IRs to the individual clicks will overlap in time, giving rise to complex interactions that have not been fully understood in the human cochlea. The perceptual consequences of these BM IR interactions are of interest as lead-lag click pairs are often used to study localization and the precedence effect. The present study aimed at characterizing perceptual consequences of BM IR interactions in individual listeners based on click-evoked otoacoustic emissions (CEOAEs) and auditory brainstem responses (ABRs). Lag suppression, denoting the level difference between the CEOAE or wave-V response amplitude evoked by the first and the second clicks, was observed for inter-click intervals (ICIs) between 1 and 4 ms. Behavioral correlates of lag suppression were obtained for the same individuals by investigating the percept of the lead-lag click pairs presented either monaurally or binaurally. The click pairs were shown to give rise to fusion (i.e., the inability to hear out the second click in a lead-lag click pair), regardless of monaural or binaural presentation. In both cases, the ICI range where the percept was a fused image correlated well with the ICI range for which monaural lag suppression occurred in the CEOAE and ABR (i.e., for ICIs below 4.3 ms). Furthermore, the lag suppression observed in the wave-V amplitudes to binaural stimulation did not show additional contributions to the lag suppression obtained monaurally, suggesting that peripheral lag suppression up to the level of the brainstem is dominant in the perception of the precedence effect.

  8. Aplastic anaemia preceding acute lymphoblastic leukaemia in an adult with isolated deletion of chromosome 9q.

    LENUS (Irish Health Repository)

    Kelly, Kevin

    2008-12-01

    Aplastic anaemia (AA) can precede acute lymphoblastic leukaemia (ALL) in 2% of children but this is rarely reported to occur in adults. A 21-year-old male presented with bone marrow failure and bone marrow biopsy showed a profoundly hypocellular marrow. He recovered spontaneously but represented 2 months later when he was diagnosed with pre-B acute lymphoblastic leukaemia. Chromosomal examination revealed 46,XY,del(9)(q13q34). To the best of our knowledge this is the first case to be reported of aplasia preceding ALL with 9q minus as the sole chromosomal abnormality.

  9. Dengue Preceding Diabetic Ketoacidosis Dear Editor;

    Directory of Open Access Journals (Sweden)

    Viroj Wiwanitkit

    2013-12-01

    Full Text Available Diabetic ketoacidosis (DKA is an important hyperglycemic complication of diabetes mellitus. Infection is confirmed as an important underlying etiology of DKA. Here, the author presents an interesting case of dengue preceding DKA. The case is a 61-year-old female presenting to the physician with the complaint of high fever without relief by self-prescription of acetaminophen. She had an underlying disease, diabetes mellitus (DM. Her body temperature was 39.4 degrees Celsius and her complete blood count showed an important finding: thrombocytopenia (platelet count = 85.000. The serological test was done and the diagnosis of dengue hemorrhagic fever was finally confirmed. This case was treated by standard fluid replacement therapy (normal saline regimen. On day 3, the patient developed new symptoms, frequent urination (more than 3 times in an hour, abdominal pain, nausea, vomiting and rapid breathing. Complete blood count was done but platelet count was within normal limit at this time. However, the urinalysis showed many positive findings, sugar 4+ and ketone 3+. Her additional blood chemistry results showed a blood glucose level of 454 mg/dL and positive serum ketone. The patient was finally diagnosed to have DKA and endocrinologists were consulted for the management. Of interest, this is a simple case of DKA but the interesting issue is the underlying condition leading to DKA in this patient. Although there are many reports confirming that infection can induce DKA, this is the first reported case of dengue preceding DKA. Indeed, there is a previous report from Thailand on a female patient presented to the physician with concurrent DKA and dengue infection (1. However, DM had not previously been diagnosed in the present case. The dengue infection is common in the tropical world and DM is also the important emerging health problem in this area. Some reports note that DM can be an aggravating factor in the development of dengue shock (2,3. There is

  10. Extension of the preceding birth technique.

    Science.gov (United States)

    Aguirre, A

    1994-01-01

    The Brass-inspired Preceding Birth Technique (PBT), is an indirect estimation technique with low costs of administration. PBT involves asking women at a time close to delivery about the survival of the preceding births. The proportion dead is close to the probability of dying between the birth and the second birthday or an index of early childhood mortality (II or Q). Brass and Macrae have determined that II is an estimate of mortality between birth and an age lower than the birth interval or around 4/5 of the birth interval. Hospital and clinic data are likely to include a concentration of women with lower risks of disease because of higher educational levels and socioeconomic status. A simulation of PBT data from the World Fertility Survey for Mexico and Peru found that the proportions of previously dead children were 0.156 in Peru and 0.092 in Mexican home deliveries. Maternity clinic proportions were 0.088 in Peru and 0.066 in Mexico. Use of clinic and hospital data collection underestimated mortality by 32% in Peru and 15% in Mexico. Another alternative was proposed: interviewing women at some other time than delivery. If the interview was during a child/infant intervention after delivery, the subsample would still be subject to a bias, but this problem could be overcome by computing the weighted average of the actual probability of the older child being dead and the conditional probability of the younger child being dead or both younger and older children being dead. Correction factors could be applied using the general standard of the logit life table system of Brass. Calculation of a simple average of the ages of the younger children could provide enough information to help decide which tables to use. Five surveys were selected for testing the factors of dependence between probabilities of death of successive siblings: Bangladesh, Lesotho, Kenya, Ghana, and Guyana. Higher mortality was related to lower dependency factors between the probabilities of death

  11. Immediation (Cultures of Immediacy)

    DEFF Research Database (Denmark)

    Kacunko, Slavko

    2017-01-01

    The 21st century´s media praxis is increasingly characterized by the emerging “cultural principle”, “condition” or “culture of immediacy”. The processes summarized under the term immediation suggest the closure of the spatio-temporal “gap” between agencies and the media involved, resulting...... with a complex interplay of social-, security-, science- and economy-related issues. The growing interest in immediation confirms its status as a new but as yet underestimated paradigm for the arts, sciences and humanities which calls for a future-focused inquiry into the cultures of immediacy. However......, in academic and popular discourse, the focus is on documenting either (societal) challenges or (technical) solutions. This paper seeks to address this imbalance by responding to an urgent need for a systematic understanding of immediation’s major forms of appearance: 1. today´s worldwide closed...

  12. Observation on clinical effects of immediate application of three kinds of intrauterine device at abortion for 12 months%人工流产即时放置3种宫内节育器12个月临床效果观察

    Institute of Scientific and Technical Information of China (English)

    柴健; 马文侠; 吴延红; 张军喜; 马颖辉; 蒋丽芳

    2012-01-01

    目的:观察Tcu380A、宫型200、活性γ型3种宫内节育器(IUD)人工流产即时放置的临床效果.方法:选择在医院门诊就诊、符合研究标准、自愿参加研究的人工流产妇女150例为观察对象,随即分为3组各50例,采用生存分析软件进行分析.结果:12个月随访率为93.33%,无1例人工流产术并发症发生.Tcu380A脱落终止率为4.21/每百妇女年,宫型200和活性r型为0,3组比较差异无统计学意义(P>0.05);宫型200、γ型活性两组因症取出率分别为4.00和2.00/每百妇女年,高于Tcu380A组,3组比较差异无统计学意义(P>0.05).结论:人工流产即时放置宫内节育器不增加子宫穿孔、盆腔感染等并发症发生.Tcu380A、宫型200、活性γ型3种IUD安全、有效,适宜人工流产后即时放置.%Objective; To observe the clinical effects of immediate application of Tcu380A intrauterine device (IUD) , uterine -shape IUD, and active γ - shape IUD at abortion. Methods; A total of 150 women who underwent artificial abortion in outpatient department in the hospital, met the criteria, and participated in the study of their own were selected as observation objects, then they were divided into three groups, 50 women in each group, survival analysis software was used for analysis. Results; The follow - up rate at 12 months was 93. 33% . No complications of artificial abortion occurred. The removal rate of Tcu380A IUD was 4. 21% per year, no IUD removal occurred in uterine - shape IUD and active -γ - shape IUD, there was no statistically significant difference among the three groups ( P > 0. 05 ) . The medical removal rates of uterine - shape IUD and active -γ - shape IUD were 4. 00% per year and 2. 00% per year, respectively, which were higher than that of Tcu380A IUD, there was no statistically significant difference among the three groups (P >0. 05 ) . Conclusion; Immediate application of IUD at abortion cant increase the complications, such as uterine

  13. Grammar Engineering Support for Precedence Rule Recovery and Compatibility Checking

    NARCIS (Netherlands)

    Bouwers, E.; Bravenboer, M.; Visser, E.

    2007-01-01

    A wide range of parser generators are used to generate parsers for programming languages. The grammar formalisms that come with parser generators provide different approaches for defining operator precedence. Some generators (e.g. YACC) support precedence declarations, others require the grammar to

  14. Respiratory Infections Precede Adult-Onset Asthma

    OpenAIRE

    2011-01-01

    BACKGROUND: Respiratory infections in early life are associated with an increased risk of developing asthma but there is little evidence on the role of infections for onset of asthma in adults. The objective of this study was to assess the relation of the occurrence of respiratory infections in the past 12 months to adult-onset asthma in a population-based incident case-control study of adults 21-63 years of age. METHODS/PRINCIPAL FINDINGS: We recruited all new clinically diagnosed cases of a...

  15. Stability in the choice of method during the period preceding a suicide attempt and in attempt repeaters

    Directory of Open Access Journals (Sweden)

    Eberhard A. Deisenhammer

    Full Text Available Background and Objectives: Understanding the mental processes preceding a suicidal act is important for the potential to intervene. This study investigates stability and possible changes of suicide methods considered during the time immediately preceding a suicide attempt. Methods: Patients who had attempted suicide were interviewed shortly thereafter with regard to whether there was a change in the conception of the method to be used during the period preceding the attempt. In addition, the course of methods applied in previous suicide attempts was assessed in attempt repeaters. Results: In total, 130 patients were included. In 63.1% one method only was envisaged during the entire suicidal crisis, in 26.9% the initial and the actual method differed. Stability rate was higher in those older than 40 years, if the duration of the suicidal crisis was ≤ 60 minutes and if a non-violent suicide method was initially intended. Of repeaters, 46.5% used the same method in all recorded attempts. Use of a non-violent method in the first suicide attempt predicted method stability in subsequent attempts. Conclusions: Focusing on one single suicide method during the time immediately preceding a suicide attempt is common. Reduced flexibility to rapidly switch mentally to another method may contribute to explain the effectiveness of limiting access to suicide means for suicide prevention.

  16. 2. A Study to Assess Problems Encountered by Immediate Family ...

    African Journals Online (AJOL)

    Esem

    the problems experienced by immediate families in caring for ... between monthly income and experiencing financial problems by the ... enable them have an improved quality of life. ..... developing liaison services to meet the health needs.

  17. A Precedent-setting Case of Dynamic Triggering

    Science.gov (United States)

    Gomberg, J. S.

    2013-12-01

    On October 28, 2012 the M7.7 Haida Gwaii, British Columbia earthquake broke the southern end of the Queen Charlotte plate-boundary fault system. Less than 3 months later on January 5, 2013 the M7.5 Craig, Alaska earthquake broke the same fault system ~385 km to the northwest. In its public statements about the Craig earthquake, the US Geological Survey noted its likely causal connection with the Haida Gwaii earthquake three months earlier. This inference was based on the improbability of two large earthquakes with recurrence intervals of hundreds of years or more on the same fault system occurring within the same 3-month interval by chance (the Poisson probability is ~.0004% assuming a 100 yr recurrence interval). What physical processes plausibly connect these two events? Although of the correct sign to encourage failure, static stress changes were more than an order of magnitude smaller than triggering thresholds documented elsewhere, and the duration between the events was too small for accrual of significant visco-elastic stress changes. The M7.7 Haida Gwaii earthquake was noteworthy in many aspects, but most remarkable was that the seismic waves it radiated probably dynamically triggered the M7.5 Craig earthquake thereby setting two new important precedents. First, the magnitude of the triggered earthquake exceeds all previously documented cases of dynamic triggering of frictional, shear failure earthquakes. Second, the extraordinarily large amplitude (peak velocities in excess of 1 cm/s) and long duration (several 100 sec) triggering waves likely resulted from trapping of energy within a sedimentary trough, rather than from focusing due to source effects as in most previous examples of clear dynamic triggering. Unlike source characteristics that vary unpredictably from event to event, the permanence of structural features that act as wave-guides suggests enhanced triggering probabilities in this and likely the numerous other settings. In these settings

  18. Rehabilitation with immediate denture

    Directory of Open Access Journals (Sweden)

    Mayelin de la Caridad Suárez González

    2015-06-01

    Full Text Available This is the case of a 42-year-old male patient, with past history of good health, active worker, who referred refusal to the period of tooth loss both for his own personality and work responsibility. On intra-buccal examination, his central superior and inferior incisors showed plenty of tooth decay that got most of his teeth structures; besides, on X-ray examination, horizontal bone loss is observed at third apical level of the present teeth and mobility grade III and IV, for what their extraction is indicated. From the prosthetic point of view, he was diagnosed as a superior and inferior partial edentulous patient, Kennedy class I. It was decided to rehabilitate by immediate superior and inferior total denture, performing previous multiple extractions with corrective alveoloplasty and alveolectomy. With the surgical and appliances treatment, excellent results were achieved, showing the effectiveness of this treatment.

  19. Pregnancy and employment leave: legal precedents and future policy.

    Science.gov (United States)

    Gardin, S K; Richwald, G A

    1986-01-01

    An estimated 85% of female workers in the US become pregnant during their working lives; 62% of married US women were employed for some period during the 12 months preceding childbirth. Historically, US legislation has assumed a protectionist policy with regard to restricting prenatal and postpartum employment, yet this stance has not been backed up by protection of income, benefits, reinstatement, or seniority. The passage in 1964 of Title VII of the Federal Civil Rights Act banning discrimination on the basis of sex triggered a long string of legal battles fought on the premise that pregnancy is a disability. As a result of Congressional efforts, an amendment to Title VII--the Pregnancy Discrimination Act--was passed in 1978. This law requires that women disabled due to pregnancy or childbirth be provided with the same benefits as those provided other disabled employees. However, the law does not require an employer who does not provide disability benefits, paid sick leave, or medical benefits to other employees to provide them to pregnant women. A weakness of existing legislation is its failure to address the difficulties inherent in accommodating childbearing women in the labor force. Accommodation under the current employment system results in productivity disruption and financial losses for both employer and employee. In all other major industrial countries, maternity benefits such as paid leave before and after childbirth, reinstatement rights, and nursing breaks on the job are guaranteed through national legislation. Such benefits emanate from acknowledgment of women's essential participation in the labor force as well as their unique ability to give birth. Under a more flexible employment system, equal protection would not result in the denial of maternity leave to female employees, but rather the provision parental leave to male and female employees.

  20. The South African Constitutional Court's Use Of Foreign Precedent ...

    African Journals Online (AJOL)

    MJM Venter

    Empirical Study of the Use of Foreign Precedents by the South African .... empirical survey follows both a quantitative and a qualitative approach by ..... purposes.77 The Court compared some of the approaches in the judgments of the US.

  1. On a learning precedence graph concept for the automotive industry

    OpenAIRE

    Hanne Klindworth; Christian Otto; Armin Scholl

    2010-01-01

    Assembly line balancing problems (ALBP) consist in assigning the total workload for manufacturing a product to stations of an assembly line as typically applied in automotive industry. The distribution of the tasks to the stations is due to restrictions which can be expressed in a precedence graph. However, automotive manufacturers usually do not know complete precedence graphs describing the production processes of their models. Unfortunately, the known approaches for graph generation are no...

  2. Immediate reaction to clarithromycin.

    Science.gov (United States)

    Gangemi, S; Ricciardi, L; Fedele, R; Isola, S; Purello-D'Ambrosio, F

    2001-01-01

    We present the case of bronchospastic reaction to clarithromycin had during a drug challenge test. Personal allergic history was negative for respiratory allergies and positive for adverse drug reactions to general and regional anesthesia and to ceftriaxone. After the administration of 1/4 of therapeutic dose of clarithromycin the patient showed dyspnea, cough and bronchospasm in all the lung fields. The positivity of the test was confirmed by the negativity to the administration of placebo. The quickness and the clinical characteristic of the adverse reaction suggest a pathogenic mechanism of immediate-type hypersensitivity. On reviewing the literature we have found no reports of bronchospastic reaction to clarithromycin. Macrolides are a class of antibiotics mainly used in the last years in place of beta-lactams because of a broad spectrum of action and a low allergic power. In fact, there are few reports on allergic reactions to these molecules. Clarithromycin is one of the latest macrolides, characterised by the presence of a 14-carbon-atom lactone ring as erythromycin, active on a wide spectrum of pathogens.

  3. Immediate retransplantation for pancreas allograft thrombosis.

    Science.gov (United States)

    Hollinger, E F; Powelson, J A; Mangus, R S; Kazimi, M M; Taber, T E; Goble, M L; Fridell, J A

    2009-04-01

    Early pancreas allograft failure most commonly results from thrombosis and requires immediate allograft pancreatectomy. Optimal timing for retransplantation remains undefined. Immediate retransplantation facilitates reuse of the same anatomic site before extensive adhesions have formed. Some studies suggest that early retransplantation is associated with a higher incidence of graft loss. This study is a retrospective review of immediate pancreas retransplants performed at a single center. All cases of pancreas allograft loss within 2 weeks were examined. Of 228 pancreas transplants, 12 grafts were lost within 2 weeks of surgery. Eleven of these underwent allograft pancreatectomy for thrombosis. One suffered anoxic brain injury and was not a retransplantation candidate, one was retransplanted at 3.5 months and nine patients underwent retransplantation 1-16 days following the original transplant. Of the nine early retransplants, one pancreas was lost to heparin-induced thrombocytopenia, one recipient died with function at 2.9 years and the other grafts continue to function at 76-1137 days (mean 572 days). One-year graft survival for early retransplantation was 89% compared to 91% for all pancreas transplants at our center. Immediate retransplantation following pancreatic graft thrombosis restores durable allograft function with outcomes comparable to first-time pancreas transplantation.

  4. Associative processes in immediate recency

    National Research Council Canada - National Science Library

    Howard, Marc W; Venkatadass, Vijay; Norman, Kenneth A; Kahana, Michael J

    2007-01-01

    .... If associative processes contribute to immediate recency, as predicted by the temporal context account, the neighbors of the initial presentation of the repeated item should show enhanced recall...

  5. 14 CFR 314.20 - Regular monthly computation.

    Science.gov (United States)

    2010-01-01

    ... full-time employment level is 92 percent or less of any of the carrier's preceding 12 monthly levels... the carrier, and add to the reported employment levels, the number of positions that were vacant in... employees deprived of employment because of a strike, as reported monthly by carriers in accordance...

  6. Late Cretaceous (Maestrichtian) Calcareous Nannoplankton Biogeography with Emphasis on Events Immediately Preceding the Cretaceous/Paleocene Boundary

    Science.gov (United States)

    1993-02-01

    Yucatan Peninsula ( Mexico ) was proposed as the site of the K/P boundary impact (Hildebrand et al., 1991). In contrast to extraterrestrial causes of...Paleotemperatures. Spoleto, July 26-27, 1965. Consiglio Nazionale delle Richerche, Laboratorio di Geologia Nucleare, Pisa, 1-22. 3 Crux, J. A., 1991...Jacobsen, S. B., and Boynton, W. V., 1991. Chicxulub Crater: A possible Cretaceous/Tertiary boundary impact crater on the Yucatin Peninsula, Mexico . lgl.Lvg

  7. Preceding trauma in childhood hematogenous bone and joint infections.

    Science.gov (United States)

    Pääkkönen, Markus; Kallio, Markku J T; Lankinen, Petteri; Peltola, Heikki; Kallio, Pentti E

    2014-03-01

    Preceding trauma may play a role in the etiology and pathogenesis of hematogenous bone and joint infections. Among 345 children with an acute hematogenous bone and/or joint infection, 20% reported trauma during a 2-week period leading to infection. Blunt impact, bruises, or excoriations were commonly reported. The rate was similar to that in the general pediatric population obtained from the literature. In the study group, patients with and without trauma were similar in age, serum C-reactive protein and erythrocyte sedimentation rate, length of hospitalization, and late sequelae. Preceding minor trauma did not prove to be significant as an etiological or as a prognostic factor.

  8. Pedi-cap color change precedes a significant increase in heart rate during neonatal resuscitation.

    Science.gov (United States)

    Blank, Doug; Rich, Wade; Leone, Tina; Garey, Donna; Finer, Neil

    2014-11-01

    Heart rate is the most important indicator of infant well-being during neonatal resuscitation. The Nellcor Pedi-Cap turns gold when exposed to exhaled gas with CO₂>15 mmHg. The aim of this study was to determine if Pedi-Cap gold color change during neonatal resuscitation precedes an increase in heart rate in babies with bradycardia receiving mask ventilation. This was a single-center retrospective review of video recordings and physiologic data of newborns with bradycardia receiving mask positive pressure ventilation during neonatal resuscitation. Subjects were included if the baby's HRCap gold color change compared to the HR after Pedi-Cap gold color change. Forty-one newborns during the study period had HRCap. The median heart rate 10s prior to Pedi-Cap gold color change was 75 BPM (IQR 62-85) and increased to 136 BPM (IQR 113-158) 30 s after gold color change (pCap gold color change to 52 ± 17% 30s after gold color change (p=0.001). Colorimetric CO₂ detection during mask positive pressure ventilation in neonatal resuscitation precedes a significant increase in heart rate and SpO₂. The Pedi-Cap can be easily applied during resuscitation, requires no electricity, provides immediate feedback and may be a useful, simple tool early in resuscitation and may be especially useful in resource limited settings. Copyright © 2014 Elsevier Ireland Ltd. All rights reserved.

  9. Immediate loading of dental implants.

    Science.gov (United States)

    Henry, P J; Liddelow, G J

    2008-06-01

    The purpose of this review is to explore the concept of immediate loading as it pertains to dental implants and the indications for clinical practice. The definition of immediate loading will be considered together with a review of the relevant literature in an attempt to provide evidence-based guidelines for successful implementation into practice. A search of electronic databases including Medline, PubMed and the Cochrane Database of Systematic Reviews was undertaken using the terms "immediate loading'', "dental implants'', "immediate function'', "early loading'', "oral implants'', "immediate restoration'' and "systematic review''. This was supplemented by handsearching in peer-reviewed journals and cross-referenced with the articles accessed. Emphasis was given to systematic reviews and controlled clinical trials. A definition of immediate loading was suggested pertinent to the realities of logistics in clinical practice with respect to application and time frame. The literature was evaluated and shown to be limited with significant shortcomings. Guidelines and recommendations for clinical protocols were suggested and illustrated by examples of case types with a minimum of 1-3 years follow-up. A list of additional references for further reading was provided. Within the limitations of this review, there is evidence to suggest that immediate loading protocols have demonstrated high implant survival rates and may be cautiously recommended for certain clinical situations. However, more high level evidence studies, preferably randomized controlled trials (RCTs), over a long time frame are required to show a clear benefit over more conventional loading protocols.

  10. Metrical expectations from preceding prosody influence perception of lexical stress.

    Science.gov (United States)

    Brown, Meredith; Salverda, Anne Pier; Dilley, Laura C; Tanenhaus, Michael K

    2015-04-01

    Two visual-world experiments tested the hypothesis that expectations based on preceding prosody influence the perception of suprasegmental cues to lexical stress. The results demonstrate that listeners' consideration of competing alternatives with different stress patterns (e.g., 'jury/gi'raffe) can be influenced by the fundamental frequency and syllable timing patterns across material preceding a target word. When preceding stressed syllables distal to the target word shared pitch and timing characteristics with the first syllable of the target word, pictures of alternatives with primary lexical stress on the first syllable (e.g., jury) initially attracted more looks than alternatives with unstressed initial syllables (e.g., giraffe). This effect was modulated when preceding unstressed syllables had pitch and timing characteristics similar to the initial syllable of the target word, with more looks to alternatives with unstressed initial syllables (e.g., giraffe) than to those with stressed initial syllables (e.g., jury). These findings suggest that expectations about the acoustic realization of upcoming speech include information about metrical organization and lexical stress and that these expectations constrain the initial interpretation of suprasegmental stress cues. These distal prosody effects implicate online probabilistic inferences about the sources of acoustic-phonetic variation during spoken-word recognition.

  11. Impact of preceding crop on alfalfa competitiveness with weeds

    Science.gov (United States)

    Organic producers would like to include no-till practices in their farming systems. We are seeking to develop a continuous no-till system for organic farming, based on a complex rotation that includes a 3-year sequence of alfalfa. In this study, we evaluated impact of preceding crop on weed infest...

  12. Cross-frequency interactions in the precedence effect.

    Science.gov (United States)

    Shinn-Cunningham, B G; Zurek, P M; Durlach, N I; Clifton, R K

    1995-07-01

    This paper concerns the extent to which the precedence effect is observed when leading and lagging sounds occupy different spectral regions. Subjects, listening under headphones, were asked to match the intracranial lateral position of an acoustic pointer to that of a test stimulus composed of two binaural noise bursts with asynchronous onsets, parametrically varied frequency content, and different interaural delays. The precedence effect was measured by the degree to which the interaural delay of the matching pointer was independent of the interaural delay of the lagging noise burst in the test stimulus. The results, like those of Blauert and Divenyi [Acustica 66, 267-274 (1988)], show an asymmetric frequency effect in which the lateralization influence of a lagging high-frequency burst is almost completely suppressed by a leading low-frequency burst, whereas a lagging low-frequency burst is weighted equally with a leading high-frequency burst. This asymmetry is shown to be the result of an inherent low-frequency dominance that is seen even with simultaneous bursts. When this dominance is removed (by attenuating the low-frequency burst) the precedence effect operates with roughly equal strength both upward and downward in frequency. Within the scope of the current study (with lateralization achieved through the use of interaural time differences alone, stimuli from only two frequency bands, and only three subjects performing in all experiments), these results suggest that the precedence effect arises from a fairly central processing stage in which information is combined across frequency.

  13. High Body Mass Index in Adolescent Girls Precedes Psoriasis Hospitalization

    DEFF Research Database (Denmark)

    Bryld, L.E.; Sørensen, T.I.A.; Andersen, Klaus Kaae

    2010-01-01

    Psoriasis is associated with being overweight, but the temporal relationship is not known. This historical cohort study tested whether severe psoriasis resulting in hospitalization in adulthood was preceded by excess increase in age-adjusted body mass index, a known risk factor in childhood for b...

  14. Deactivation of the Parahippocampal Gyrus Preceding Auditory Hallucinations in Schizophrenia

    NARCIS (Netherlands)

    Diederen, Kelly M. J.; Neggers, Sebastiaan F. W.; Daalman, Kirstin; Blom, Jan Dirk; Goekoop, Rutger; Kahn, Rene S.; Sommer, Iris E. C.

    2010-01-01

    Objective: Activation in a network of language-related regions has been reported during auditory verbal hallucinations. It remains unclear, however, how this activation is triggered. Identifying brain regions that show significant signal changes preceding auditory hallucinations might reveal the ori

  15. Experimental Evidence for a Cochlear Source of the Precedence Effect

    DEFF Research Database (Denmark)

    Bianchi, Federica; Verhulst, Sarah; Dau, Torsten

    2013-01-01

    The precedence effect (PE) refers to the dominance of directional information carried by a direct sound (lead) over the spatial information contained in its multiple reflections (lags) in sound localization. Although the processes underlying the PE have been largely investigated, the extent to wh...

  16. Radiation Alert Immediate Disclosure Project

    Data.gov (United States)

    National Aeronautics and Space Administration — Invocon's Radiation Alert Immediate Disclosure (RAID) system is a miniature, low-power, real-time, active radiation badge. It is designed for monitoring personnel,...

  17. Impairment of adolescent hippocampal plasticity in a mouse model for Alzheimer's disease precedes disease phenotype.

    Directory of Open Access Journals (Sweden)

    Daniela Hartl

    Full Text Available The amyloid precursor protein (APP was assumed to be an important neuron-morphoregulatory protein and plays a central role in Alzheimer's disease (AD pathology. In the study presented here, we analyzed the APP-transgenic mouse model APP23 using 2-dimensional gel electrophoresis technology in combination with DIGE and mass spectrometry. We investigated cortex and hippocampus of transgenic and wildtype mice at 1, 2, 7 and 15 months of age. Furthermore, cortices of 16 days old embryos were analyzed. When comparing the protein patterns of APP23 with wildtype mice, we detected a relatively large number of altered protein spots at all age stages and brain regions examined which largely preceded the occurrence of amyloid plaques. Interestingly, in hippocampus of adolescent, two-month old mice, a considerable peak in the number of protein changes was observed. Moreover, when protein patterns were compared longitudinally between age stages, we found that a large number of proteins were altered in wildtype mice. Those alterations were largely absent in hippocampus of APP23 mice at two months of age although not in other stages compared. Apparently, the large difference in the hippocampal protein patterns between two-month old APP23 and wildtype mice was caused by the absence of distinct developmental changes in the hippocampal proteome of APP23 mice. In summary, the absence of developmental proteome alterations as well as a down-regulation of proteins related to plasticity suggest the disturption of a normally occurring peak of hippocampal plasticity during adolescence in APP23 mice. Our findings are in line with the observation that AD is preceded by a clinically silent period of several years to decades. We also demonstrate that it is of utmost importance to analyze different brain regions and different age stages to obtain information about disease-causing mechanisms.

  18. Cardiac tamponade preceding skin involvement in systemic sclerosis

    Directory of Open Access Journals (Sweden)

    L. Bozzola

    2011-09-01

    Full Text Available The frequency of pericardial involvement in Systemic Sclerosis (SSc is high on autoptic or echocardiographic studies, but the clinical recognition of pericarditis with or without effusion is rare. We describe a case of a 71-year-old female with no previous history of heart disease, who presented with a large pericardial effusion and tamponade that required pericardial drain. She had suffered from Raynaud’s phenomenon since 25 years. Six weeks after hospital discharge she complained of skin hardening on left leg. Pericardial tamponade is a very rare manifestation of SSc and occurs both early or late in the course of the disease, but in our case it preceded the recognition of scleroderma. We have only identified two other cases of pericardial effusion preceding cutaneous involvement in scleroderma.

  19. A Visual lexicon to Handle Semantic Similarity in Design precedents

    DEFF Research Database (Denmark)

    Restrepo-Giraldo, John Dairo

    2007-01-01

    . The shaping and establishing of this image is supported by creating sketches, collages, models and other types of external representations. This process is largely supported by the use of design precedents. In design, precedents provide the frame of reference for the development of new solution principles...... for visual information. The reason is that the algorithms available cannot recognize what the image contains (in semantic terms) but humans can, and with great facility. This ability was reflected in the searching process of the designers in our studies. It is very natural for them to expect living room......The adequate use of existing knowledge, and not only the creation of completely new solutions, is also an important part of creative thinking. When conceiving a solution, designers oftentimes report having a vague image of the form that will embody the final solution to the design task at hand...

  20. A Visual lexicon to Handle Semantic Similarity in Design precedents

    DEFF Research Database (Denmark)

    Restrepo-Giraldo, John Dairo

    2007-01-01

    by many researchers that have tried to support the process by providing computer tools. Many of these tools have the drawback of relying on metadata added to the image by the editor of the collection. In all the tools studies for this research, such metadata contained, among other things, descriptions......The adequate use of existing knowledge, and not only the creation of completely new solutions, is also an important part of creative thinking. When conceiving a solution, designers oftentimes report having a vague image of the form that will embody the final solution to the design task at hand....... The shaping and establishing of this image is supported by creating sketches, collages, models and other types of external representations. This process is largely supported by the use of design precedents. In design, precedents provide the frame of reference for the development of new solution principles...

  1. Human electrophysiological examination of buildup of the precedence effect.

    Science.gov (United States)

    Dimitrijevic, Andrew; Stapells, David R

    2006-07-31

    Event-related potential correlates of the buildup of precedence effect were examined. Buildup is a type of precedence effect illusion in which perception changes (from hearing two clicks to hearing one click) during a click train. Buildup occurs faster for right-leading than left-leading clicks. Continuous click trains that changed leading sides every 15 clicks were presented. Event-related potential N1 amplitudes became smaller with click train for right-leading only. N1 latency decreased with click trains. Mismatch negativity was seen after lead-lag sides were changed. When the perceived change differed in location (left-to-right), mismatch negativity peaked earlier than when the perceived change differed in location and number of clicks (right-to-left). Results suggest that buildup relates to: N1 refractoriness, event-related potential 'lead domination' and mismatch negativity differences.

  2. ARMA-GARCH Model and temporal precedence between stock indices

    Directory of Open Access Journals (Sweden)

    Diego Garcia Angelico

    2016-03-01

    Full Text Available Faced with the need for risk valuation of financial assets, investors demand sophisticated methods of modeling that can judge the variability of their investments. At the same time, financial globalization has been characterized by common movements and trends between different international markets. In this context, the main objective of this paper was to model the statistical volatility of the Bovespa Index (Ibovespa and the Dow Jones Industrial Average Index, using ARMA-GARCH adjustments, in addition to checking the existence of a long- -term balance and temporal precedence between these variables, using the Johansen co-integration and Granger causality tests, respectively. The results established a higher heterogeneous variance for Ibovespa and the existence of temporal precedence for the Dow Jones Index, despite the absence of any long-term balance between the series. It is understood that the latter behavior may have been caused by the existing difference between the conditional heteroscedasticity of each index.

  3. Extended precedence preservative crossover for job shop scheduling problems

    Science.gov (United States)

    Ong, Chung Sin; Moin, Noor Hasnah; Omar, Mohd

    2013-04-01

    Job shop scheduling problems (JSSP) is one of difficult combinatorial scheduling problems. A wide range of genetic algorithms based on the two parents crossover have been applied to solve the problem but multi parents (more than two parents) crossover in solving the JSSP is still lacking. This paper proposes the extended precedence preservative crossover (EPPX) which uses multi parents for recombination in the genetic algorithms. EPPX is a variation of the precedence preservative crossover (PPX) which is one of the crossovers that perform well to find the solutions for the JSSP. EPPX is based on a vector to determine the gene selected in recombination for the next generation. Legalization of children (offspring) can be eliminated due to the JSSP representation encoded by using permutation with repetition that guarantees the feasibility of chromosomes. The simulations are performed on a set of benchmarks from the literatures and the results are compared to ensure the sustainability of multi parents recombination in solving the JSSP.

  4. Motility precedes egress of malaria parasites from oocysts

    Science.gov (United States)

    Klug, Dennis; Frischknecht, Friedrich

    2017-01-01

    Malaria is transmitted when an infected Anopheles mosquito deposits Plasmodium sporozoites in the skin during a bite. Sporozoites are formed within oocysts at the mosquito midgut wall and are released into the hemolymph, from where they invade the salivary glands and are subsequently transmitted to the vertebrate host. We found that a thrombospondin-repeat containing sporozoite-specific protein named thrombospondin-releated protein 1 (TRP1) is important for oocyst egress and salivary gland invasion, and hence for the transmission of malaria. We imaged the release of sporozoites from oocysts in situ, which was preceded by active motility. Parasites lacking TRP1 failed to migrate within oocysts and did not egress, suggesting that TRP1 is a vital component of the events that precede intra-oocyst motility and subsequently sporozoite egress and salivary gland invasion. DOI: http://dx.doi.org/10.7554/eLife.19157.001 PMID:28115054

  5. Explicit Precedence Constraints in Safety-Critical Java

    DEFF Research Database (Denmark)

    Puffitsch, Wolfgang; Noulard, Eric; Pagetti, Claire

    2013-01-01

    Safety-critical Java (SCJ) aims at making the amenities of Java available for the development of safety-critical applications. The multi-rate synchronous language Prelude facilitates the specification of the communication and timing requirements of complex real-time systems. This paper combines...... to provide explicit support for precedence constraints. We present the considerations behind the design of this extension and discuss our experiences with a first prototype implementation based on the SCJ implementation of the Java Optimized Processor....

  6. Monthly Meteorological Reports

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Monthly forms that do not fit into any regular submission. Tabulation sheets and generic monthly forms designed to capture miscellaneous monthly observations.

  7. Adherence with Universal Precautions after Immediate, Personalized Performance Feedback

    Science.gov (United States)

    Luke, Molli M.; Alavosius, Mark

    2011-01-01

    We evaluated the effects of immediate, personalized performance feedback on adherence with hand hygiene by health-care staff in the context of a multiple baseline design across participants. Target behaviors reached mastery levels and were maintained near 100% throughout 2 months of maintenance probes. (Contains 1 table and 1 figure.)

  8. Immediate Versus Early Loading and Conventional Loading in Implant Dentistry

    Directory of Open Access Journals (Sweden)

    Hassan Maghaireh

    2013-12-01

    Full Text Available To minimize the risk of implant failures after their placement, dental implants are traditionally kept load-free for 3 to 8 months to establish osseointegration before connecting the prosthetic super-structure (conventional loading. However, implant dentists are under continuous pressure from the media and patients to speed up the treatment and reduce number of visits during the implant therapy. Immediate implant loading can also reduce the cost and might also improve aesthetics as claimed by some surgeons. This pressure from the media, patients and dentists was behind introducing changes into the loading protocols and nowadays implants are loaded early and even immediately and it would be useful to know whether there is a difference in success rates between immediately and early loaded implants compared with conventionally loaded implants. It is well known that whenever a clinician is faced with a clinical question, the answer(s should be evidence based to avoid the risk of bias as opinion based answers can be misleading and can cause more failures in the dental practice. This mini-review aims to evaluate the effects of (1 immediate (within 1 week, (2 early (between 1 week and 2 months, and (3 conventional (after 2 months loading of osseointegrated dental implants. The review found no evidence that attaching artificial teeth either immediately, after 6 weeks (early or after at least 3 months (conventional led to any important differences in the failure of the implant or the artificial tooth, or to the amount of bone which surrounded the implant (any bone loss would be an undesirable consequence. However, we found a trend of more failures and complications with early loading when compared to immediate or conventional loading. More research is needed in this area. - See more at: http://smiledentaljournal.com/article.php?id=59#sthash.mniQLIcf.dpuf

  9. The association between preceding drought occurrence and heat waves in the Mediterranean

    Science.gov (United States)

    Russo, Ana; Gouveia, Célia M.; Ramos, Alexandre M.; Páscoa, Patricia; Trigo, Ricardo M.

    2017-04-01

    A large number of weather driven extreme events has occurred worldwide in the last decade, namely in Europe that has been struck by record breaking extreme events with unprecedented socio-economic impacts, including the mega-heatwaves of 2003 in Europe and 2010 in Russia, and the large droughts in southwestern Europe in 2005 and 2012. The last IPCC report on extreme events points that a changing climate can lead to changes in the frequency, intensity, spatial extent, duration, and timing of weather and climate extremes. These, combined with larger exposure, can result in unprecedented risk to humans and ecosystems. In this context it is becoming increasingly relevant to improve the early identification and predictability of such events, as they negatively affect several socio-economic activities. Moreover, recent diagnostic and modelling experiments have confirmed that hot extremes are often preceded by surface moisture deficits in some regions throughout the world. In this study we analyze if the occurrence of hot extreme months is enhanced by the occurrence of preceding drought events throughout the Mediterranean area. In order to achieve this purpose, the number of hot days in the regions' hottest month will be associated with a drought indicator. The evolution and characterization of drought was analyzed using both the Standardized Precipitation Evaporation Index (SPEI) and the Standardized Precipitation Index (SPI), as obtained from CRU TS3.23 database for the period 1950-2014. We have used both SPI and SPEI for different time scales between 3 and 9 months with a spatial resolution of 0.5°. The number of hot days and nights per month (NHD and NHN) was determined using the ECAD-EOBS daily dataset for the same period and spatial resolution (dataset v14). The NHD and NHN were computed, respectively, as the number of days with a maximum or minimum temperature exceeding the 90th percentile. Results show that the most frequent hottest months for the Mediterranean

  10. Does a preceding hand wash and drying time after surgical hand disinfection influence the efficacy of a propanol-based hand rub?

    Directory of Open Access Journals (Sweden)

    Kohlmann Thomas

    2006-06-01

    Full Text Available Abstract Background Recently, a propanol-based hand rub has been described to exceed the efficacy requirements of the European standard EN 12791 in only 1.5 min significantly. But the effect of a 1 min preceding hand wash and the effect of one additional minute for evaporation of the alcohol after its application on the efficacy after a 1.5 min application time has never been studied. Methods We have investigated a propanol-based hand rub (Sterillium®, based on 45% propan-2-ol, 30% propan-1-ol and 0.2% mecetronium etilsulfate in three variations: with (A and without (B a 1 min hand wash before the disinfection of 1.5 min with immediate sampling after the disinfection; and (C without a hand wash before the disinfection but with sampling 1 min after the disinfection. The efficacy of the three variations was compared to the reference treatment of EN 12791. All experiments were performed in a Latin-square design with 20 volunteers. Pre- and post-values (immediate and after 3 hr were obtained according to EN 12791. Results The 3 min reference disinfection reduced resident hand bacteria on average by 1.8 log10 steps (immediate effect and 1.4 log10-steps (sustained effect respectively. Method A was equally effective as the reference (immediate efficacy: 1.5 log10-steps; sustained efficacy: 1.6 log10-steps. Method B seemed to be more effective (immediate efficacy: 2.3 log10-steps; sustained efficacy: 1.7 log10-steps. Method C revealed the best efficacy (immediate efficacy: 2.3 log10-steps; sustained efficacy: 2.0 log10-steps. A comparison of all three treatment variations and the reference treatment revealed a significant difference for the immediate efficacy (p = 0.026; Friedman test, but not for the sustained efficacy (p = 0.430. A post-hoc-test for the immediate efficacy indicated a significant difference between methods A and C (p Conclusion An application of the propanol-based hand rub for 1.5 min after 1 min hand wash fulfills the efficacy

  11. Vitiligo disease triggers: psychological stressors preceding the onset of disease.

    Science.gov (United States)

    Silverberg, Jonathan I; Silverberg, Nanette B

    2015-05-01

    Vitiligo is the loss of skin pigmentation caused by autoimmune destruction of melanocytes. Little is known about the impact of psychological stressors preceding vitiligo onset on symptoms associated with vitiligo and the extent of disease. We performed a questionnaire-based study of 1541 adults with vitiligo to evaluate the impact of psychological stressors in this patient population. Psychological stressors should be considered as potential disease triggers in vitiligo patients, and screening of vitiligo patients for psychological stressors and associated symptoms should be included in routine assessment.

  12. Design of a Secure RFID Authentication Scheme Preceding Market Transactions

    Directory of Open Access Journals (Sweden)

    Chin-Ling Chen

    2011-01-01

    Full Text Available In recent years, as RFID reader equipment is ever more widely deployed in handled devices, the importance of security problems among RFID reader, tags and server have obviously gained increased attention. However, there are still many security issues preceding transactions; these issues are well worth discussing. In this paper, we propose a novel authentication scheme, conforming EPC C1G2 standards, at a low implementation cost for market application. In order to achieve mutual authentication, the proposed scheme integrates fingerprint biometrics, related cryptology and a hash function mechanism to ensure the security of the transmitted messages. The proposed scheme also can resist known attacks.

  13. USING PRECEDENTS FOR REDUCTION OF DECISION TREE BY GRAPH SEARCH

    Directory of Open Access Journals (Sweden)

    I. A. Bessmertny

    2015-01-01

    Full Text Available The paper considers the problem of mutual payment organization between business entities by means of clearing that is solved by search of graph paths. To reduce the decision tree complexity a method of precedents is proposed that consists in saving the intermediate solution during the moving along decision tree. An algorithm and example are presented demonstrating solution complexity coming close to a linear one. The tests carried out in civil aviation settlement system demonstrate approximately 30 percent shortage of real money transfer. The proposed algorithm is planned to be implemented also in other clearing organizations of the Russian Federation.

  14. Nephrotic syndrome due to immunoglobulin M mesangial glomerulonephritis preceding juvenile idiopathic arthritis.

    Science.gov (United States)

    Voyer, Luis E; Alvarado, Caupolican; Cuttica, Rubén J; Balestracci, Alejandro; Zardini, Marta; Lago, Néstor

    2013-05-21

    The association between nephrotic syndrome and juvenile idiopathic arthritis have rarely been described in pediatric patients. We report a child with steroid-responsive nephrotic syndrome, with frequent relapses, who presented with a new relapse of nephrotic syndrome associated with arthritis and uveitis at 21 months in remission after treatment with chlorambucil. Juvenile idiopathic arthritis was diagnosed and kidney biopsy examination showed mesangial glomerulonephritis with immunoglobulin M deposits. To our knowledge, only 2 cases of nephrotic syndrome preceding juvenile idiopathic arthritis have been reported, one without histopathology assessment and the other with minimal change disease. Although mesangial glomerulonephritis with nephrotic syndrome and juvenile idiopathic arthritis could have been coincidental, the immune pathogenic mechanism accepted for both diseases suggests they could be related.

  15. Perturbation of old knowledge precedes integration of new knowledge.

    Science.gov (United States)

    Fang, Xiaoping; Perfetti, Charles A

    2017-05-01

    The importance of memory consolidation in integrating new knowledge has received much recent attention in the field of word learning. Less examined is the change in existing word knowledge as a result of learning, which we hypothesize to occur prior to the opportunity for consolidation. To test this, we had participants learn new meanings for known words and novel words. Then they performed a one-back task on a list of words that included the trained words followed by words that probed either their new or original meanings while EEGs were recorded. A probe word related to the new meaning of the preceding trained word did not show an N400 reduction compared to an unrelated word, suggesting that the new meaning had not been fully integrated, consistent with one account of complementary learning systems. However, when the probe word was related to the original meaning of the preceding trained word a perturbation effect was observed, indicated by a larger negativity at the central midline cluster (Cz) within 500-700 ms when the trained word had a new meaning than when presented as an exposure control. The perturbation effect suggests that even before a new meaning has become integrated with a word form, the attempt to learn a new meaning temporarily makes the original meaning of a word less accessible. Copyright © 2017 Elsevier Ltd. All rights reserved.

  16. Continental warming preceding the Palaeocene-Eocene thermal maximum.

    Science.gov (United States)

    Secord, Ross; Gingerich, Philip D; Lohmann, Kyger C; Macleod, Kenneth G

    2010-10-21

    Marine and continental records show an abrupt negative shift in carbon isotope values at ∼55.8 Myr ago. This carbon isotope excursion (CIE) is consistent with the release of a massive amount of isotopically light carbon into the atmosphere and was associated with a dramatic rise in global temperatures termed the Palaeocene-Eocene thermal maximum (PETM). Greenhouse gases released during the CIE, probably including methane, have often been considered the main cause of PETM warming. However, some evidence from the marine record suggests that warming directly preceded the CIE, raising the possibility that the CIE and PETM may have been linked to earlier warming with different origins. Yet pre-CIE warming is still uncertain. Disentangling the sequence of events before and during the CIE and PETM is important for understanding the causes of, and Earth system responses to, abrupt climate change. Here we show that continental warming of about 5 °C preceded the CIE in the Bighorn Basin, Wyoming. Our evidence, based on oxygen isotopes in mammal teeth (which reflect temperature-sensitive fractionation processes) and other proxies, reveals a marked temperature increase directly below the CIE, and again in the CIE. Pre-CIE warming is also supported by a negative amplification of δ(13)C values in soil carbonates below the CIE. Our results suggest that at least two sources of warming-the earlier of which is unlikely to have been methane-contributed to the PETM.

  17. Expectations from preceding prosody influence segmentation in online sentence processing.

    Science.gov (United States)

    Brown, Meredith; Salverda, Anne Pier; Dilley, Laura C; Tanenhaus, Michael K

    2011-12-01

    Previous work examining prosodic cues in online spoken-word recognition has focused primarily on local cues to word identity. However, recent studies have suggested that utterance-level prosodic patterns can also influence the interpretation of subsequent sequences of lexically ambiguous syllables (Dilley, Mattys, & Vinke, Journal of Memory and Language, 63:274-294, 2010; Dilley & McAuley, Journal of Memory and Language, 59:294-311, 2008). To test the hypothesis that these distal prosody effects are based on expectations about the organization of upcoming material, we conducted a visual-world experiment. We examined fixations to competing alternatives such as pan and panda upon hearing the target word panda in utterances in which the acoustic properties of the preceding sentence material had been manipulated. The proportions of fixations to the monosyllabic competitor were higher beginning 200 ms after target word onset when the preceding prosody supported a prosodic constituent boundary following pan-, rather than following panda. These findings support the hypothesis that expectations based on perceived prosodic patterns in the distal context influence lexical segmentation and word recognition.

  18. Cellular contraction precedes membrane depolarization in Vorticella convallaria

    Science.gov (United States)

    Shiono; Naitoh

    1997-01-01

    Application of a mechanical stimulus to the cell body of the peritrich ciliate Vorticella convallaria evoked an all-or-nothing membrane depolarization, the large pulse. This was always accompanied by an all-or-nothing cellular contraction, and simultaneous recordings of the two events revealed that the large pulse was always preceded by the cellular contraction. A smaller graded membrane depolarization (the medium pulse) was sometimes produced in response to a weaker mechanical stimulus. The medium pulse was accompanied by a small, graded, localized contraction of the cell body and was occasionally followed by a large pulse. When a large pulse occurred during a medium pulse, it reached the same peak level as that of a large pulse evoked without a preceding medium pulse. When a medium pulse occurred during a medium pulse, summation of the two pulses was observed. Sustained contraction causes V. convallaria to become rounded, and in this state a mechanical stimulus stronger than that used to evoke the large pulse evoked a graded depolarizing mechanoreceptor potential in the cell. We conclude that both the large and medium pulses are caused by an inward receptor current that is activated mechanically following contraction of the cell body. A localized contraction evokes a small mechanoreceptor current, causing a medium pulse. An all-or-nothing contraction evokes a saturated, all-or-nothing mechanoreceptor current, causing a large pulse.

  19. Changes in autonomic activity preceding onset of nonsustained ventricular tachycardia

    Science.gov (United States)

    Osaka, M.; Saitoh, H.; Sasabe, N.; Atarashi, H.; Katoh, T.; Hayakawa, H.; Cohen, R. J.

    1996-01-01

    Background: The triggering role of the autonomic nervous system in the initiation of ventricular tachycardia has not been established. To investigate the relationship between changes in autonomic activity and the occurrence of nonsustained ventricular tachycardia (NSVT) we examined heart rate variability (HRV) during the 2-hour period preceding spontaneous episodes of NSVT. Twenty-four subjects were identified retrospectively as having had one episode of NSVT during 24-hour Holter ECC recording. Methods: We measured the mean interval between normal heats (meanRR), the standard deviation of the intervals between beats (SD), the percentage of counts of sequential intervals between normal beats with a change of >50 ms (%RR50), the logarithms of low- and high-frequency spectral components (lnLF, lnHF) of HRV for sequential 10-minute segments preceding NSVT. The correlation dimension (CDim) of HRV was calculated similarly for sequential 20-minute segments. We assessed the significance of the time-course change of each marker over the 120-minute period prior to NSVT onset. Results: MeanRR (P parasympathetic activity, perhaps in conjunction with an increase in sympathetic activity, may trigger NSVT.

  20. [Oral rehydration immediately after appendectomy].

    Science.gov (United States)

    Azabache, W; Johanson, L

    1989-01-01

    An experimental study of 20 patients with appendicitis was carried out in order to know if after the appendectomy they tolerate the hidratation with rehidratant salts by mouth in place of endovenous hydratation. The oral hydratation was indicated in all the cases immediately after the operation and only was one failure (5%). In the 95% the oral hydratation was tolerated, 45% without gastric symptoms, 35% with mild gastric symptoms and in 15% with moderate gastric symptoms. The association of gentamycin-metronidazol administered by intramuscular and oral way respectively was used in 100% of the patients. In 80% as profilaxis and in 20% as treatment. Two cases had complication as sepsis of the wound one of the profilactic group (5.9%) and another of the treatment group. In conclusion the oral hydratation with rehydrating salts were tolerated for the patients immediately after the appendectomy.

  1. Factors predicting suicidal ideation in the preceding 12 months among patients attending a community psychiatric outpatient clinic.

    LENUS (Irish Health Repository)

    Anyansi, Tochukwu E

    2013-06-01

    Predictive factors are used to alert the clinician to the necessity of carrying out a suicide risk assessment in those patients whose demographic and clinical characteristics suggest the possibility of suicide.

  2. IMMEDIATE VERSUS DELAYED LOADING IMPLANTS: RATIONALE AND CONTROVERSIES.

    Science.gov (United States)

    Corradini, G; Delle Donne, U; Boni, W; Tettamanti, L; Tagliabue, A

    2015-01-01

    Loading implants immediately after their position in alveolar bone crest is a procedure that has become popular in the last decade. The aim of this study is to evaluate the survival rate of 811 immediate loaded implants (ILIs). In the period between January 2008 and December 2013, 877 patients (498 females and 379 males) were operated at the BDD private Practice Clinic (Milan, Italy). The mean post-surgical follow-up was 30±17 months (max – min, 84 – 1). One thousasnd three hundred and eighty-six fixtures (EDIERRE Implant System SpA, Genoa, Italy) were evaluated in the present study, 811 immediately loaded and 575 loaded after 3 months. All patients underwent the same surgical protocol and agreed to participate in a post-operative check-up program. SPSS program was used for statistical analysis. Survival rate (SVR) was 97.3% since only 38 fixtures were lost from a total of 1,348 implants. Cross-tabulation between failures demonstrated slight but significant worse results for ILIs (p= 0.037). There were 28 failures out of 811 ILIs whereas only 10 fixtures were lost out of 565 implants loaded after 3 months. Immediate loading performed in selected cases is a reliable tool for oral rehabilitation.

  3. Severe immediate reaction to nabumetone.

    Science.gov (United States)

    Gonzalo-Garijo, M A; Cordobés-Duran, C; Lamilla-Yerga, A M; Moreno-Gastón, I

    2007-01-01

    Nabumetone is a nonsteroidal antiinflammatory (NSAID) prodrug that inhibits cyclooxygenase-2. It has been recommended as a safe alternative in most patients with hypersensitivity reactions to NSAIDs. Systemic reactions caused by nabumetone are not frequent. We report 2 cases of immediate systemic reactions due to nabumetone. The first case involved a 68-year-old woman who developed immediate generalized pruritus, erythema, morbilliform eruption, swollen tongue sensation, diarrhea, and hypotension after the ingestion of a single dose of nabumetone. In the second case, a 77-year-old woman developed generalized pruritus, palm erythema, colic abdominal pain, diarrhea, dizziness, tightness of the chest, dyspnea, and hypotension immediately after oral intake of nabumetone. Both patients had previously tolerated this drug. Since these episodes, they have avoided nabumetone. Skin prick tests with nabumetone (10 and 100 mg/mL) were negative. Oral challenge tests with other NSAIDs, even of the same group as nabumetone, were negative in both patients. The mechanisms responsible for the reaction were not established.

  4. Immediate Desensitization in Teeth Affected by Amelogenesis Imperfecta.

    Science.gov (United States)

    Moreira, Rudá França; Figueiredo, Rossana Gomes; Oliveira, Henrique Eduardo; Fonseca, Ana Christina Lamosa da; Miranda, Mauro Sayão de

    2016-01-01

    The aim of this paper was to describe a clinical case of immediate dental desensitization using a self-etch adhesive system in an adolescent patient diagnosed with amelogenesis imperfecta (AI). AI was associated with severe tooth sensitivity, treated by the application of a universal adhesive system for desensitization of the teeth affected by AI. Reduction of tooth sensitivity was assessed using a visual analog scale during all reevaluations. The technique was effective for reducing tooth sensitivity. It was concluded that the adhesive system for tooth desensitization had an immediate effect and maintained its effectiveness during a 12-month follow-up period.

  5. Immediate and delayed cochlear neuropathy after noise exposure in pubescent mice

    DEFF Research Database (Denmark)

    Jensen, Jane Bjerg; Lysaght, Andrew C; Liberman, M Charles

    2015-01-01

    to 16 months post exposure. Mice exposed to neuropathic noise demonstrated immediate cochlear synaptopathy by 24 hours post exposure, and delayed neurodegeneration characterized by axonal retraction at 8 months, and spiral ganglion cell loss at 8-16 months post exposure. Although the damage...

  6. Natural gas monthly, January 1997

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1997-01-01

    This publication, the Natural Gas Monthly, presents the most recent data on natural gas supply, consumption, and prices from the Energy Information Administration (EIA). Of special interest in this issue are two articles summarizing reports recently published by EIA. The articles are {open_quotes}Natural Gas Productive Capacity{close_quotes} and {open_quotes}Outlook for Natural Gas Through 2015,{close_quotes} both of which precede the {open_quotes}Highlights{close_quotes} section. With this issue, January 1997, changes have been made to the format of the Highlights section and to several of the tabular and graphical presentations throughout the publication. The changes to the Highlights affect the discussion of developments in the industry and the presentation of weekly storage data. An overview of the developments in the industry is now presented in a brief summary followed by specific discussions of supply, end-use consumption, and prices. Spot and futures prices are discussed as appropriate in the Price section, together with wellhead and consumer prices.

  7. Monthly Weather Review

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Supplements to the Monthly Weather Review publication. The Weather Bureau published the Monthly weather review Supplement irregularly from 1914 to 1949. The...

  8. Proposing Chinese Pharmacists Month

    Institute of Scientific and Technical Information of China (English)

    2009-01-01

    @@ Dear Pharmacists: Today I would like to share with you about the American Pharmacists Month which is celebrated in October every year.This month-long observance is promoted by American Pharmacist Association.

  9. Inner Segment Ellipsoid Band and Cone Outer Segment Tips Changes Preceding Macular Hole Development in a Young Patient

    Directory of Open Access Journals (Sweden)

    Mariana Harasawa

    2014-01-01

    Full Text Available Purpose. Pathophysiology of macular hole (MH is not yet well defined but the advances of spectral domain optical coherence tomography (SD-OCT give us access to further detailed imaging. We report a case with macular inner segment ellipsoid (ISe band loss and cone outer segment tips (COST line changes seen in SD-OCT preceding MH appearance in a young patient. Methods. 21-year-old woman presented with a partial central scotoma, metamorphopsia, and a 20/25 vision in her right eye. Past medical history was positive for laser assisted in situ keratomileusis (LASIK surgery 7 months ago with no complications. Macular SD-OCT showed ISe band loss and COST line elevation. She was followed a month later with visual acuity deteriorating to 20/200 and a full thickness MH. Results. The patient underwent a pars plana vitrectomy with internal limiting membrane peeling. Her visual acuity 2 months later was 20/20. Conclusion. SD-OCT can identify preliminary changes, yet to be described, preceding MH formation. Our patient demonstrated ISe band loss and COST abnormalities on SD-OCT a month prior to MH development. SD-OCT should be considered in young patients with subtle visual symptoms and mild changes in visual acuity that are not readily explained by ophthalmological exam.

  10. Revisiting Precede-Proceed: A Leading Model for Ecological and Ethical Health Promotion

    Science.gov (United States)

    Porter, Christine M.

    2016-01-01

    Background: The Precede-Proceed model has provided moral and practical guidance for the fields of health education and health promotion since Lawrence Green first developed Precede in 1974 and Green and Kreuter added Proceed in 1991. Precede-Proceed today remains the most comprehensive and one of the most used approaches to promoting health.…

  11. Hepatic glucose intolerance precedes hepatic steatosis in the male aromatase knockout (ArKO mouse.

    Directory of Open Access Journals (Sweden)

    Michelle L Van Sinderen

    Full Text Available Estrogens are known to play a role in modulating metabolic processes within the body. The Aromatase knockout (ArKO mice have been shown to harbor factors of Metabolic syndrome with central adiposity, hyperinsulinemia and male-specific hepatic steatosis. To determine the effects of estrogen ablation and subsequent replacement in males on whole body glucose metabolism, three- and six-month-old male ArKO mice were subjected to whole body glucose, insulin and pyruvate tolerance tests and analyzed for ensuing metabolic changes in liver, adipose tissue, and skeletal muscle. Estrogen-deficient male ArKO mice showed increased gonadal adiposity which was significantly reduced upon 17β-estradiol (E2 treatment. Concurrently, elevated ArKO serum leptin levels were significantly reduced upon E2 treatment and lowered serum adiponectin levels were restored to wild type levels. Three-month-old male ArKO mice were hyperglycemic, and both glucose and pyruvate intolerant. These phenotypes continued through to 6 months of age, highlighting a loss of glycemic control. ArKO livers displayed changes in gluconeogenic enzyme expression, and in insulin signaling pathways upon E2 treatment. Liver triglycerides were increased in the ArKO males only after 6 months of age, which could be reversed by E2 treatment. No differences were observed in insulin-stimulated ex vivo muscle glucose uptake nor changes in ArKO adipose tissue and muscle insulin signaling pathways. Therefore, we conclude that male ArKO mice develop hepatic glucose intolerance by the age of 3 months which precedes the sex-specific development of hepatic steatosis. This can be reversed upon the administration of exogenous E2.

  12. Enhanced Precedence Scheduling Algorithm with Dynamic Time Quantum (EPSADTQ

    Directory of Open Access Journals (Sweden)

    G. Siva Nageswara Rao

    2015-07-01

    Full Text Available This study proposes a new algorithm which is a logical extension of the popular Round Robin CPU scheduling algorithm. The Round Robin algorithm can be effective only if the time quantum is chosen accurately. Even by taking mean average of burst times as time quantum, the performance of the RR cannot be improved beyond a certain point. However, the novel method proposed here, suggests that a priority be assigned to each process based on balanced precedence factor. The novel method also uses mean average as a time quantum. Experiments are conducted in order to measure the effectiveness of this novel method. The results clearly showed that EPSADTQ is superior to RR and PSMTQ and its variants. EPSADTQ resulted in a significant reduction of the no. of context switches, average waiting time and average turnaround time.

  13. Cancer preceding Wegener's granulomatosis: a case-control study

    DEFF Research Database (Denmark)

    Faurschou, Mikkel; Mellemkjaer, Lene; Sørensen, Inge Juul

    2009-01-01

    .4; 95% CI 1.1, 38) based on two patients, who developed testis cancer >10 years before WG. The overall prevalence of malignancies diagnosed skin cancer occurred with an increased prevalence within this time...... interval (OR 4.0; 95% CI 1.4, 12). CONCLUSIONS: We did not find clear evidence of an increased prevalence of preceding cancer in our WG cohort, indicating that shared risk factors are of minor importance for the excess of malignancies that occur in WG patients after the vasculitis diagnosis. Furthermore...... randomly for each patient from the Danish Central Population Register. Information on malignancies was obtained through the Danish Cancer Registry. Occurrence of malignancies before WG diagnosis among patients and before WG diagnosis of their matched case among controls (reference date) was compared...

  14. Immediate re-transplantation following early kidney transplant thrombosis.

    LENUS (Irish Health Repository)

    Phelan, Paul J

    2012-02-01

    Allograft thrombosis is a devastating early complication of renal transplantation that ultimately leads to allograft loss. We report here on our experience of nine cases of immediate re-transplantation following early kidney transplant thrombosis at a single centre between January 1990 and June 2009. The mean age was 42.9 years at time of transplant. For seven patients, the allograft thrombosis was their first kidney transplant and seven of the nine cases had a deceased donor transplant. The initial transplants functioned for a mean of 1.67 days and the patients received a second allograft at a mean of 3.1 days after graft failure. All of the re-transplants worked immediately. Four allografts failed after a mean of 52.5 months (2-155 months). Two of these died with a functioning allograft, one failed owing to chronic allograft nephropathy and one owing to persistent acute cellular rejection. The remaining five patients still have a functioning allograft after a mean of 101.8 months (7-187 months). One year allograft and patient survival after re-transplantation were 87.5% and 100% respectively (after 5 years, both were 57%). Immediate re-transplantation following early kidney transplant thrombosis can be a success. It may be considered in selected cases after allograft thrombosis.

  15. Immediate re-transplantation following early kidney transplant thrombosis.

    LENUS (Irish Health Repository)

    Phelan, Paul J

    2011-08-01

    Allograft thrombosis is a devastating early complication of renal transplantation that ultimately leads to allograft loss. We report here on our experience of nine cases of immediate re-transplantation following early kidney transplant thrombosis at a single centre between January 1990 and June 2009. The mean age was 42.9 years at time of transplant. For seven patients, the allograft thrombosis was their first kidney transplant and seven of the nine cases had a deceased donor transplant. The initial transplants functioned for a mean of 1.67 days and the patients received a second allograft at a mean of 3.1 days after graft failure. All of the re-transplants worked immediately. Four allografts failed after a mean of 52.5 months (2-155 months). Two of these died with a functioning allograft, one failed owing to chronic allograft nephropathy and one owing to persistent acute cellular rejection. The remaining five patients still have a functioning allograft after a mean of 101.8 months (7-187 months). One year allograft and patient survival after re-transplantation were 87.5% and 100% respectively (after 5 years, both were 57%). Immediate re-transplantation following early kidney transplant thrombosis can be a success. It may be considered in selected cases after allograft thrombosis.

  16. Immediate Debridement and Reconstruction with

    Directory of Open Access Journals (Sweden)

    Hyoseob Lim

    2012-01-01

    Full Text Available Background Poststernotomy mediastinitis is a rare, but life-threatening complication,thus early diagnosis and proper management is essential for poststernotomy mediastinitis.The main treatment for mediastinitis is aggressive debridement. Several options exist forreconstruction of defects after debridement. The efficacy of immediate debridement andreconstruction with a pectoralis major muscle flap designed for the defect immediately afterthe diagnosis of poststernotomy mediastinitis is demonstrated.Methods Between September 2009 and June 2011, 6 patients were referred to the Departmentof Plastic and Reconstructive Surgery and the Department of Thoracic and CardiovascularSurgery of Ajou University Hospital for poststernotomy mediastinitis. All of the patientsunderwent extensive debridement and reconstruction with pectoralis major muscle flaps,advanced based on the pedicle of the thoracoacromial artery as soon as possible followingdiagnosis. A retrospective review of the 6 cases was performed to evaluate infection control,postoperative morbidity, and mortality.Results All patients had complete wound closures and reduced severity of infections basedon the erythrocyte sedimentation rate and C-reactive protein levels and a reduction inpoststernal fluid collection on computed tomography an average of 6 days postoperatively.A lack of growth of organisms in the wound culture was demonstrated after 3 weeks. Therewere no major wound morbidities, such as hematomas, but one minor complication requireda skin graft caused by skin flap necrosis. No patient expired after definitive surgery.Conclusions Immediate debridement and reconstruction using a pectoralis major muscle flapis a safe technique for managing infections associated with poststernotomy mediastinitis,and is associated with minimal morbidity and mortality.

  17. Evaluation of stability of immediately placed implants in infected sockets

    Directory of Open Access Journals (Sweden)

    Uma Shankar Pal

    2013-01-01

    Full Text Available Purpose: To describe a protocol for the immediate placement of implant into the infected alveolar socket. Materials and Methods: In this study, a total number of 40 implants were placed immediately into the extraction sockets. Each case had a different periapical condition (acute, endodontic and periodontal infection. Great care had been taken in debridement of the socket, extraction of tooth/teeth and guided bone regeneration along with the use of pre-operative and post-operative anti-microbial agent. Results: All except three implants were osseo-integrated within 6 months to 1 year. The complications were due to the extraction procedure and bone regeneration process. Conclusion: Predisposing factors for failures are incomplete debridement of the socket, poor oral hygiene, incomplete closure of the wound, and systemic factors like hormones. From this study, we may conclude that immediate implants are a viable treatment option for patients with periapical infections.

  18. Foreshock patterns preceding large earthquakes in the subduction zone of Chile

    Science.gov (United States)

    Minadakis, George; Papadopoulos, Gerassimos A.

    2016-04-01

    Some of the largest earthquakes in the globe occur in the subduction zone of Chile. Therefore, it is of particular interest to investigate foreshock patterns preceding such earthquakes. Foreshocks in Chile were recognized as early as 1960. In fact, the giant (Mw9.5) earthquake of 22 May 1960, which was the largest ever instrumentally recorded, was preceded by 45 foreshocks in a time period of 33h before the mainshock, while 250 aftershocks were recorded in a 33h time period after the mainshock. Four foreshocks were bigger than magnitude 7.0, including a magnitude 7.9 on May 21 that caused severe damage in the Concepcion area. More recently, Brodsky and Lay (2014) and Bedford et al. (2015) reported on foreshock activity before the 1 April 2014 large earthquake (Mw8.2). However, 3-D foreshock patterns in space, time and size were not studied in depth so far. Since such studies require for good seismic catalogues to be available, we have investigated 3-D foreshock patterns only before the recent, very large mainshocks occurring on 27 February 2010 (Mw 8.8), 1 April 2014 (Mw8.2) and 16 September 2015 (Mw8.4). Although our analysis does not depend on a priori definition of short-term foreshocks, our interest focuses in the short-term time frame, that is in the last 5-6 months before the mainshock. The analysis of the 2014 event showed an excellent foreshock sequence consisting by an early-weak foreshock stage lasting for about 1.8 months and by a main-strong precursory foreshock stage that was evolved in the last 18 days before the mainshock. During the strong foreshock period the seismicity concentrated around the mainshock epicenter in a critical area of about 65 km mainly along the trench domain to the south of the mainshock epicenter. At the same time, the activity rate increased dramatically, the b-value dropped and the mean magnitude increased significantly, while the level of seismic energy released also increased. In view of these highly significant seismicity

  19. A PRECEDE-PROCEED based educational intervention in quality of life of women-headed households in Iran

    Science.gov (United States)

    Solhi, Mahnaz; Shabani Hamedan, Marziyeh; Salehi, Masoud

    2016-01-01

    Background: Women-headed households are more exposed to social damages than other women. Such condition remarkably influences the women’s health-related life quality. The present study is aimed to investigate the effect of an educational intervention in quality of life of women-headed households under protection of Tehran Welfare Organization, in 2015. Methods: In this quasi-experimental study with control group, 180 women-headed households participated. Sampling method was random allocation. Data collection tools were Life Quality standard questionnaire (WHOQOL-BREF) and a researcher-made questionnaire about structures of ecological and educational diagnosis phase of PRECEDE-PROCEED model. Validity and reliability of the questionnaire approved in a primary study. Based on the results obtained from the primary study, the intervention was performed in the case group only. Participants were followed one and three months after intervention. Data were analyzed through SPSS v. 15 software using descriptive and analytical tests. Results: Before intervention no significant difference was observed among the mean scores of life quality, behavioral factors, and knowledge, enabling, and reinforcing factors in the two groups. But, one month and three months after intervention a significant difference was observed between the mean scores of these variables (in five instances p<0.001). Conclusion: Intervention through the PRECEDE-PROCEED model improved the women-headed households’ quality of life. The innovation of this study is using such intervention on quality of life in women-headed households for the first time. PMID:28210582

  20. Fate of premalignant clones during the asymptomatic phase preceding lymphoid malignancy.

    Science.gov (United States)

    Moulés, Vincent; Pomier, Carole; Sibon, David; Gabet, Anne-Sophie; Reichert, Michal; Kerkhofs, Pierre; Willems, Luc; Mortreux, Franck; Wattel, Eric

    2005-02-15

    Almost all cancers are preceded by a prolonged period of clinical latency during which a combination of cellular events helps move carcinogen-exposed cells towards a malignant phenotype. Hitherto, investigating the fate of premalignant cells in vivo remained strongly hampered by the fact that these cells are usually indistinguishable from their normal counterparts. Here, for the first time, we have designed a strategy able to reconstitute the replicative history of the bona fide premalignant clone in an animal model, the sheep experimentally infected with the lymphotropic bovine leukemia virus. We have shown that premalignant clones are early and clearly distinguished from other virus-exposed cells on the basis of their degree of clonal expansion and genetic instability. Detectable as early as 0.5 month after the beginning of virus exposure, premalignant cells displayed a two-step pattern of extensive clonal expansion together with a mutation load approximately 6 times higher than that of other virus-exposed cells that remained untransformed during the life span of investigated animals. There was no fixation of somatic mutations over time, suggesting that they regularly lead to cellular death, partly contributing to maintain a normal lymphocyte count during the prolonged premalignant stage. This equilibrium was finally broken after a period of 18.5 to 60 months of clinical latency, when a dramatic decrease in the genetic instability of premalignant cells coincided with a rapid increase in lymphocyte count and lymphoma onset.

  1. Isolated Uterine Myeloid Sarcoma Preceding the Diagnosis of Acute Myeloid Leukemia.

    Science.gov (United States)

    Aleem, Aamer; Aziz, Shahid; Hussain, Sajjad; Algahtani, Fatmah; Alsaleh, Khalid

    2016-06-01

    Myeloid sarcoma (MS) is an extramedullary solid tumor composed of leukemic myeloid cells. MS is an uncommon tumor complicating acute myeloid leukemia (AML), or less often myelodysplestic syndrome (MDS) and myeloproliferative disorders. Rarely, MS may precede the systemic onset of AML, which usually follows within months. We report a 36 year-old lady who presented with a cervical-uterine mass, which proved to be MS. Initially, she had no systemic AMLand was treated with hysterectomy and systemic chemotherapy. She developed bilateral-flank pain and renal impairment after 9 months. Imaging revealed a soft-tissue mass in the para-aortic and peri-sacral region with bilateral hydronephrosis. Biopsy from the mass confirmed recurrence of MS. Bone marrow (BM) biopsy revealed 20% blasts consistent with AML. She was treated with aggressive chemotherapy and local radiotherapy. Despite these measures, she died of progressive disease. MS should be considered and treated as systemic AML, rather than an isolated mass; and we discuss management issues in such patients.

  2. Early development in Dravet syndrome; visual function impairment precedes cognitive decline.

    Science.gov (United States)

    Chieffo, Daniela; Ricci, Daniela; Baranello, Giovanni; Martinelli, Diego; Veredice, Chiara; Lettori, Donatella; Battaglia, Domenica; Dravet, Charlotte; Mercuri, Eugenio; Guzzetta, Francesco

    2011-01-01

    Aim of the study was to describe prospectively the early neuropsychological evolution including the first pre-cognitive stages of the Severe Myoclonic Epilepsy in Infancy (SMEI) or Dravet syndrome. Five cases, four of whom since before a diagnostic evidence of the Dravet syndrome, were followed up. Full clinical assessment including developmental, visual function and behaviour assessments were serially performed. In four cases, a variable onset age of cognitive decline assessed with developmental scales was preceded some months before by an impairment of visual function; the remaining patient during all the course of follow-up till 51 months of age showed a normal development without visual impairment. A cognitive decline with variable onset was generally confirmed in Dravet syndrome. The previous early impairment of visual function seems to herald the cognitive decline and provides useful prognostic information; furthermore, it possibly suggests some clues for a better understanding of the mechanisms of cognitive deterioration in this syndrome. 2010 Elsevier B.V. All rights reserved.

  3. Lithospheric Convergence Preceded Extension in the Pannonian-Carpathian System

    Science.gov (United States)

    Houseman, Gregory; Stuart, Graham; Dando, Ben; Hetenyi, Gyorgy; Lorinczi, Piroska; Hegedus, Endre; Brueckl, Ewald

    2010-05-01

    The continuing collision of the Adriatic block with European continental lithosphere has its clearest expression now in the Alpine collision zone. Recent tomographic images of the upper mantle beneath the eastern Alps and western Pannonian Basin support the interpretation that in the Early Miocene the collision zone extended further east: a steeply dipping seismically fast structure stretches downward beneath the Eastern Alps reaching to the base of the transition zone, consistent with the long history of convergence in this region. This high velocity structure also extends eastward beneath the extensional Pannonian Basin. The high velocity anomaly beneath the Basin is strongly developed in transition zone depths (410 to 660 km) but the anomaly weakens upward. High velocities beneath the center of the extensional basin are unexpected because there is substantive evidence that the onset of extension in the Pannonian domain at around 17 Ma produced rapid extension of the lithosphere and replacement of the lower part of the lithosphere by hot asthenosphere. These deeper structures, however, must be explained by the long history of convergence that preceded the extension of the basin. Further evidence of a history of sustained convergence in the present Pannonian region is found in the depression of the 660 km seismic discontinuity beneath the Alps (Lombardi et al., EPSL, 2009) and also beneath the Pannonian Basin (Hetenyi et al., GRL, 2009). The 660 km discontinuity in both places is depressed by as much as 40 km, whereas the 410 km discontinuity is at approximately nominal depths. Evidently in both regions relatively dense material derived from the mid-Miocene collision sits stagnant on top of the 660 km discontinuity, where further descent is obstructed by the negative Clapeyron slope of the spinel-to-perovskite phase transition and/or the high viscosity of the lower mantle. The rapid extension of the Intra-Carpathian Basins in the Mid-Miocene (between about 17 and

  4. Cerebral potentials preceding unilateral and simultaneous bilateral finger movements.

    Science.gov (United States)

    Kristeva, R; Keller, E; Deecke, L; Kornhuber, H H

    1979-08-01

    Cerebral potentials preceding voluntary bilateral simultaneous finger movements were investigated in 19 right-handed young adult subjects, and were compared with unilateral right-sided finger m n the same experiment. With bilateral movements, the Bereitschaftspotential (BP) was not symmetrical or larger over the dominant hemisphere, but surprisingly, it was larger over the minor hemisphere. The BP averaged -3.66 microV (S.D. 1.96) over the left precentral region and -4.82 microV (S.D. 3.73) over the right precentral region in this condition. The difference was significant at 2P less than 0.01. This difference was pronounced in precentral leads but very small and almost missing in parietal leads. The pre-motion positivity (PMP) was well developed and even larger with bilateral than with unilateral (right-sides) movements. At the vertex it averaged +1.33 microV (S.D.4.16) with bilateral movements and only +0.15 microV (S.D. 1.42) with right-sided unilateral movements (2P less than 0.05). With bilateral movements the PMP could be observed in any record, but with unilateral movements it was missing at the left precentral lead, in accordance with previous publications (Deecke et al. 1969, 1976). The motor potential (MP), measured in a bipolar record from left and right precentral leads, was larger with unilateral (-1.25 microV, S.D. 1.33) than with bilateral movements (-0.36 microV, S.D. 0.92). Onset time differences of the BP preceding unilateral and bilateral movements were very small. However, there was a tendency towards earlier onset with unilateral than with bilateral movements (1031 msec, S.D. 358, as compared with 951 msec, S.D. 305). The averaged EMG revealed differences in movement onset. Muscular contraction tended to be earlier in the right than in the left m. flexor indicis in our right-handed subjects, on the average by 16 msec (S.D. 15). With unilateral right-sided movements, the left m. flexor indicis was not silent but showed an abortive mirror activity

  5. 12 CFR 561.24 - Immediate family.

    Science.gov (United States)

    2010-01-01

    ... 12 Banks and Banking 5 2010-01-01 2010-01-01 false Immediate family. 561.24 Section 561.24 Banks and Banking OFFICE OF THRIFT SUPERVISION, DEPARTMENT OF THE TREASURY DEFINITIONS FOR REGULATIONS AFFECTING ALL SAVINGS ASSOCIATIONS § 561.24 Immediate family. The term immediate family of any natural...

  6. Immediate Sequential Bilateral Cataract Surgery

    DEFF Research Database (Denmark)

    Kessel, Line; Andresen, Jens; Erngaard, Ditte

    2015-01-01

    The aim of the present systematic review was to examine the benefits and harms associated with immediate sequential bilateral cataract surgery (ISBCS) with specific emphasis on the rate of complications, postoperative anisometropia, and subjective visual function in order to formulate evidence......-based national Danish guidelines for cataract surgery. A systematic literature review in PubMed, Embase, and Cochrane central databases identified three randomized controlled trials that compared outcome in patients randomized to ISBCS or bilateral cataract surgery on two different dates. Meta-analyses were...... performed using the Cochrane Review Manager software. The quality of the evidence was assessed using the GRADE method (Grading of Recommendation, Assessment, Development, and Evaluation). We did not find any difference in the risk of complications or visual outcome in patients randomized to ISBCS or surgery...

  7. Zegerid--immediate-release omeprazole.

    Science.gov (United States)

    2005-04-11

    The FDA has approved marketing of Zegerid powder for oral suspension (Santarus), an immediate-release formulation of the proton-pump inhibitor (PPI) omeprazole (Prilosec, and others). All other oral PPIs are delayed-release, enteric-coated formulations designed to prevent degradation of the drug by gastric acid. Each 20- or 40-mg packet of Zegerid contains 1680 mg sodium bicarbonate, which protects the drug from gastric acid degradation. A dose of Zegerid contains 460 mg of sodium, which may be excessive for some patients. Zegerid is the first oral PPI to be approved by the FDA for reduction of risk of upper GI bleeding in critically ill patients. The drug may be useful for patients who are unable to swallow and have nasogastric (NG) tubes in place. Zegerid cost $70.00 for 14 days' treatment, compared to less than $10 for 14 tablets of Prilosec OTC.

  8. Osseointegration of Immediate Transalveolar Implants

    Directory of Open Access Journals (Sweden)

    Yoel González Beriau

    2016-02-01

    Full Text Available Background: osseointegration is critical to start prosthetic rehabilitation. Objective: to describe osseointegration of immediate transalveolar implants. Methods: a prospective case series study was conducted from January 2012 to December 2013. It included all patients (75 patients with 79 implants who attended the Prosthodontics service. Age, sex, osseointegration, cause of tooth loss, region of the implant, specific tooth, bone level and keratinized gingiva around the implant, were the variables studied. Frequency distribution and statistical analysis were used for data analysis. Results: females and patients aged 31 to 45 years predominated. Osseointegration was observed in 97.4% of the implants. Nearly all implants were placed in the premaxilla and posterior maxilla, specifically in the first bicuspids. In most patients, osseointegration with bone formation occurred at the implant collar and in the presence of completely keratinized tissue, with a statistically significant association between the two variables. Conclusion: rehabilitation treatment with this type of implant led to successful osseointegration in most cases studied.

  9. Immediate response to cigarette smoke

    Energy Technology Data Exchange (ETDEWEB)

    Rees, P.J.; Chowienczyk, P.J.; Clark, T.J.

    1982-06-01

    Using an automated method of calculating airways resistance in the body plethysmograph, we have investigated changes occurring immediately after inhalation of cigarette smoke. Decreases in specific conductance occurred by the time of the first measurement seven or eight seconds after exposure to single inhalations of cigarette smoke in 12 smokers and 12 non-smokers. Less than half of the initial change was present 40 seconds after the inhalation. Initial responses were greater in the non-smokers. Responses recurred with repeated inhalations in smokers and non-smokers. Prior administration of salbutamol and ipratropium bromide significantly inhibited the response and this inhibition appeared to be greater in non-smokers. Sodium cromoglycate inhaled as a dry powder had no effect on the response.

  10. Rehearsal in immediate serial recall.

    Science.gov (United States)

    Tan, Lydia; Ward, Geoff

    2008-06-01

    We report for the first time overt rehearsal data in immediate serial recall (ISR) undertaken at three presentation rates (1, 2.5, and 5 sec/word). Two groups of participants saw lists of six words for ISR and were required either to engage in overt rehearsal or to remain silent after reading aloud the word list during its presentation. Typical ISR serial position effects were obtained for both groups, and recall increased with slower rates. When participants rehearsed, they tended to do so in a cumulative forward order up to Serial Position 4, after which the amount of rehearsal decreased substantially. There were similarities between rehearsal and recall data: Both broke down toward the end of longer sequences, and there were strong positive correlations between the maximum sequence of participants' rehearsals and their ISR performance. We interpret these data as suggesting that similar mechanisms underpin both rehearsal and recall in ISR.

  11. Hispanic Heritage Month

    Science.gov (United States)

    York, Sherry

    2004-01-01

    Hispanic heritage month is from September 15 to October 15. One problem that arises when grouping people into categories such as Hispanic or Latino is stereotyping, stereotypes can be promoted or used in this Hispanic month to promote a greater understanding of Latino cultures.

  12. Progress report, 24 months

    DEFF Research Database (Denmark)

    Juhl, Thomas Winther; Nielsen, Jakob Skov

    The work performed during the past 12 months (months 13 – 24) of the project has included the conclusion of Task 1 – Fundamental Studies and Task 2 – Multimirror Cutting Head Design. Work on Task 3 – Compact Cutting Head Design, and Task 4 – Interface Design has been carried out and the tests...... of the multimirror cutting head have been started....

  13. Progress report, 36 months

    DEFF Research Database (Denmark)

    Juhl, Thomas Winther; Nielsen, Jakob Skov

    The work performed during the past 12 months (months 13 – 24) of the project has included the conclusion of Task 1 – Fundamental Studies and Task 2 – Multimirror Cutting Head Design. Work on Task 3 – Compact Cutting Head Design, and Task 4 – Interface Design has been carried out and the tests...... of the multimirror cutting head have been started....

  14. Progress report, 36 months

    DEFF Research Database (Denmark)

    Juhl, Thomas Winther; Nielsen, Jakob Skov

    The work performed during the past 12 months (months 13 – 24) of the project has included the conclusion of Task 1 – Fundamental Studies and Task 2 – Multimirror Cutting Head Design. Work on Task 3 – Compact Cutting Head Design, and Task 4 – Interface Design has been carried out and the tests of ...

  15. Progress report, 24 months

    DEFF Research Database (Denmark)

    Juhl, Thomas Winther; Nielsen, Jakob Skov

    The work performed during the past 12 months (months 13 – 24) of the project has included the conclusion of Task 1 – Fundamental Studies and Task 2 – Multimirror Cutting Head Design. Work on Task 3 – Compact Cutting Head Design, and Task 4 – Interface Design has been carried out and the tests of ...

  16. HIGH RATES OF EVOLUTION PRECEDED THE ORIGIN OF BIRDS

    Science.gov (United States)

    Puttick, Mark N; Thomas, Gavin H; Benton, Michael J; Polly, P David

    2014-01-01

    The origin of birds (Aves) is one of the great evolutionary transitions. Fossils show that many unique morphological features of modern birds, such as feathers, reduction in body size, and the semilunate carpal, long preceded the origin of clade Aves, but some may be unique to Aves, such as relative elongation of the forelimb. We study the evolution of body size and forelimb length across the phylogeny of coelurosaurian theropods and Mesozoic Aves. Using recently developed phylogenetic comparative methods, we find an increase in rates of body size and body size dependent forelimb evolution leading to small body size relative to forelimb length in Paraves, the wider clade comprising Aves and Deinonychosauria. The high evolutionary rates arose primarily from a reduction in body size, as there were no increased rates of forelimb evolution. In line with a recent study, we find evidence that Aves appear to have a unique relationship between body size and forelimb dimensions. Traits associated with Aves evolved before their origin, at high rates, and support the notion that numerous lineages of paravians were experimenting with different modes of flight through the Late Jurassic and Early Cretaceous. PMID:24471891

  17. Promoter Methylation Precedes Chromosomal Alterations in Colorectal Cancer Development

    Directory of Open Access Journals (Sweden)

    Sarah Derks

    2006-01-01

    Full Text Available Background: Colorectal cancers are characterized by genetic and epigenetic alterations. This study aimed to explore the timing of promoter methylation and relationship with mutations and chromosomal alterations in colorectal carcinogenesis. Methods: In a series of 47 nonprogressed adenomas, 41 progressed adenomas (malignant polyps, 38 colorectal carcinomas and 18 paired normal tissues, we evaluated promoter methylation status of hMLH1, O6MGMT, APC, p14ARF, p16INK4A, RASSF1A, GATA-4, GATA-5, and CHFR using methylation-specific PCR. Mutation status of TP53, APC and KRAS were studied by p53 immunohistochemistry and sequencing of the APC and KRAS mutation cluster regions. Chromosomal alterations were evaluated by comparative genomic hybridization. Results: Our data demonstrate that nonprogressed adenomas, progressed adenomas and carcinomas show similar frequencies of promoter methylation for the majority of the genes. Normal tissues showed significantly lower frequencies of promoter methylation of APC, p16INK4A, GATA-4, and GATA-5 (P-values: 0.02, 0.02, 1.1×10−5 and 0.008 respectively. P53 immunopositivity and chromosomal abnormalities occur predominantly in carcinomas (P values: 1.1×10−5 and 4.1×10−10. Conclusions: Since promoter methylation was already present in nonprogressed adenomas without chromosomal alterations, we conclude that promoter methylation can be regarded as an early event preceding TP53 mutation and chromosomal abnormalities in colorectal cancer development.

  18. Axonal Dysfunction Precedes Motor Neuronal Death in Amyotrophic Lateral Sclerosis.

    Directory of Open Access Journals (Sweden)

    Yuta Iwai

    Full Text Available Wide-spread fasciculations are a characteristic feature in amyotrophic lateral sclerosis (ALS, suggesting motor axonal hyperexcitability. Previous excitability studies have shown increased nodal persistent sodium conductances and decreased potassium currents in motor axons of ALS patients, both of the changes inducing hyperexcitability. Altered axonal excitability potentially contributes to motor neuron death in ALS, but the relationship of the extent of motor neuronal death and abnormal excitability has not been fully elucidated. We performed multiple nerve excitability measurements in the median nerve at the wrist of 140 ALS patients and analyzed the relationship of compound muscle action potential (CMAP amplitude (index of motor neuronal loss and excitability indices, such as strength-duration time constant, threshold electrotonus, recovery cycle and current-threshold relationships. Compared to age-matched normal controls (n = 44, ALS patients (n = 140 had longer strength-duration time constant (SDTC: a measure of nodal persistent sodium current; p 5mV. Regression analyses showed that SDTC (R = -0.22 and depolarizing threshold electrotonus (R = -0.22 increased with CMAP decline. These findings suggest that motor nerve hyperexcitability occurs in the early stage of the disease, and precedes motor neuronal loss in ALS. Modulation of altered ion channel function could be a treatment option for ALS.

  19. PRECEDENTS FOR AUTHORIZATION OF CONTENTS USING DOSE RATE MEASUREMENTS

    Energy Technology Data Exchange (ETDEWEB)

    Abramczyk, G.; Bellamy, S.; Nathan, S.; Loftin, B.

    2012-06-05

    For the transportation of Radioactive Material (RAM) packages, the requirements for the maximum allowed dose rate at the package surface and in its vicinity are given in Title 10 of the Code of Federal Regulations, Section 71.47. The regulations are based on the acceptable dose rates to which the public, workers, and the environment may be exposed. As such, the regulations specify dose rates, rather than quantity of radioactive isotopes and require monitoring to confirm the requirements are met. 10CFR71.47 requires that each package of radioactive materials offered for transportation must be designed and prepared for shipment so that under conditions normally incident to transportation the radiation level does not exceed 2 mSv/h (200 mrem/h) at any point on the external Surface of the package, and the transport index does not exceed 10. Before shipment, the dose rate of the package is determined by measurement, ensuring that it conforms to the regulatory limits, regardless of any analyses. This is the requirement for all certified packagings. This paper discusses the requirements for establishing the dose rates when shipping RAM packages and the precedents for meeting these requirements by measurement.

  20. [An autopsy case of Goodpasture syndrome preceded with membranous glomerulonephritis].

    Science.gov (United States)

    Takeuchi, K; Takeda, T; Sakai, I; Taneichi, K; Shibaki, H

    1997-12-01

    Goodpasture syndrome (GS) is an autoimmune disorder characterized by the association of pulmonary hemorrhage and rapidly progressive glomerulonephritis. The pathogenesis of GS is still unknown, but was shown to be the result that antibodies directed against glomerular basement membrane (GBM) antigens could injure both glomerular and pulmonary alveolar basement membrane. And membranous glomerulonephritis (MGN) is a glomerular disease characterized by epimembranous immune deposits and basement membrane thickening. MGN typically presents with the onset of nephrotic syndrome, but it often presents with only asymptomatic proteinuria. We reported an autopsy case of GS preceded with MGN. A 70-year-old man was admitted to our hospital with acute renal failure in May 2, 1996. Percutaneous renal biopsy demonstrated a crescentic glomerulonephritis associated with MGN and linear immunofluorescent staining of the basement membrane with antibodies to IgG. Two weeks later on admission he began to develop slight hemoptysis and chest X-ray showed pulmonary hemorrhage, Furthermore, his serum anti-GBM antibodies titer was very high. He was diagnosed as GS associated with MGN and treated with plasma exchange, glucocorticoid, and cyclophosphamide. Though his symptom was improved for intensive support, he suddenly died on June 22. Autopsied lungs showed focal pulmonary hemorrhage, but were not considered to be life-threatening. The cause of the death remained unclear.

  1. Casual sequences preceding coal dust explosions; Ursachenkette einer Kohlenstaubexplosion

    Energy Technology Data Exchange (ETDEWEB)

    Cichowski, E. [Schlesische Technische Univ., Gleiwitz (Poland); Faber, M. [Bergbau-Versuchsstrecke, DMT Gas and Fire Division, Bochum (Germany)

    2002-12-01

    The paper examines the causal sequence which precedes a possible coaldust explosion in the Polish coal industry. Each occurrence is prefaced by a sequence of necessary causes. Here it is assumed that the component parts of the required causal sequence are always present when the undesired final occurrence takes place. An identification of the causality of the coal-dust explosion often complicates this process, such that both the initiation and the consequences of the explosion can be linked to various changes in the parameters associated with the working environment. The essential aspect of the accident hazard and of the ensuing risk to the winning operation results from the causality factor, which is dependent on various safety deficiencies. The safety deficiencies presented can be due to parameters associated with the working environment or to human actions. (orig.) [German] Im vorliegenden Beitrag wird die Ursachenkette betrachtet, die einer moeglichen Kohlenstaubexplosion im polnischen Steinkohlenbergbau vorausgeht. Jeder Folge geht eine Kette notwendiger Ursachen voraus. Dabei wird angenommen, dass Bestandteile der notwendigen Ursachenkette immer auftreten, wenn die unerwuenschte Endfolge geschieht. Die Identifizierung der Kausalitaet der Kohlenstaubexplosion kompliziert oft diesen Vorgang, so dass sowohl das Initiieren als auch die Folgen der Kohlenstaubexplosion mit verschiedenen Aenderungen der Arbeitsumweltparameter verknuepft sein koennen. Das Wesentliche der Unfallgefaehrdung und des auftretenden Risikos der Gewinnung resultiert aus der Kausalitaet, die unterschiedliche Sicherheitsdefizite bedingen. Die angefuehrten Sicherheitsdefizite koennen seitens der Arbeitsumweltparameter sowie seitens menschlicher Einfluesse auftreten. (orig.)

  2. TEC enhancement immediately before M9 mega-thrust earthquakes

    Science.gov (United States)

    Heki, Kosuke

    2012-07-01

    Earthquakes are often preceded by electromagnetic precursors, e.g. electric currents in the ground and propagation anomalies of radio waves. By monitoring the differences of the L1 and L2 carrier phases from GPS satellites, we can infer ionospheric Total Electron Content (TEC). Here I report that positive anomalies of ionospheric TEC appeared immediately before the 2011 Tohoku-Oki (Mw9.0), 2010 Chile (Maule) (Mw8.8), 2007 Bengkulu (Mw8.6), and 2004 Sumatra-Andaman (Mw9.2) earthquakes. Coseismic vertical movements of the surface excite acoustic and internal gravity waves, causing coseismic ionospheric disturbances (CID), and GPS-TEC data showed that they occurred about ten minutes after these earthquakes. In addition to them, positive TEC anomalies were found to start 60-40 minutes before these earthquakes above the focal regions, and to last until the onsets of CID. In the Tohoku-Oki case, the anomaly was reached about one tenth of the background TEC immediately before the earthquake. TEC enhancements often occur irrespective of earthquakes, for example, sudden increase of TEC due to solar flares and large-scale traveling ionospheric disturbances (LSTID) propagating from the auroral oval to mid-latitude regions. These disturbances can be distinguished by carefully observing their spatial extents and movements. Geomagnetic activities were relatively high in the 2004 Sumatra-Andaman and 2011 Tohoku-Oki events, but were low in the 2007 Bengkulu and 2010 Chile events. For the Tohoku-Oki and the Bengkulu earthquakes, we analyzed the TEC time series of the same satellite and receiver pair over 120 days before and after the earthquakes, and confirmed that the precursory anomalies of the earthquakes were the largest in these periods. We also investigated three M8 class earthquakes, the 1994 Hokkaido-Toho-Oki (Mw8.3), 2006 Kuril (Mw8.2), and the 2003 Tokachi-Oki (Mw8.0) earthquakes. However, only weak precursory TEC anomalies were seen in the 1994 event, and not in the 2003

  3. Changes in visual object recognition precede the shape bias in early noun learning

    Directory of Open Access Journals (Sweden)

    Meagan N Yee

    2012-12-01

    Full Text Available Two of the most formidable skills that characterize human beings are language and our prowess in visual object recognition. They may also be developmentally intertwined. Two experiments, a large sample cross-sectional study and a smaller sample 6-month longitudinal study of 18- 24 month olds tested a hypothesized developmental link between changes in the visual object representation and noun learning. Previous findings in visual object recognition indicate that children’s ability to recognize common basic level categories from sparse structural shape representations of object shape emerges between the ages of 18 and 24 months, is related to noun vocabulary size, and is lacking in children with language delay. Other research shows that in artificial noun learning tasks, during this same developmental period, young children systematically generalize object names by shape, that this shape bias predicts future noun learning, and is lacking in children with language delay. The two experiments examine the developmental relation between visual object recognition and the shape bias for the first time. The results show that developmental changes in visual object recognition systematically preceded the emergence of the shape bias. The results suggest a developmental pathway in which early changes in visual object recognition that are themselves linked to category learning enable the discovery of higher-order regularities in category structure and thus the shape bias in novel noun learning tasks. The proposed developmental pathway has implications for understanding the role of specific experience in the development of both visual object recognition and the shape bias in early noun learning.

  4. Aberrant IgA responses to the gut microbiota during infancy precede asthma and allergy development.

    Science.gov (United States)

    Dzidic, Majda; Abrahamsson, Thomas R; Artacho, Alejandro; Björkstén, Bengt; Collado, Maria Carmen; Mira, Alex; Jenmalm, Maria C

    2017-03-01

    Although a reduced gut microbiota diversity and low mucosal total IgA levels in infancy have been associated with allergy development, IgA responses to the gut microbiota have not yet been studied. We sought to determine the proportions of IgA coating together with the characterization of the dominant bacteria, bound to IgA or not, in infant stool samples in relation to allergy development. A combination of flow cytometric cell sorting and deep sequencing of the 16S rDNA gene was used to characterize the bacterial recognition patterns by IgA in stool samples collected at 1 and 12 months of age from children staying healthy or having allergic symptoms up to 7 years of age. The children with allergic manifestations, particularly asthma, during childhood had a lower proportion of IgA bound to fecal bacteria at 12 months of age compared with healthy children. These alterations cannot be attributed to differences in IgA levels or bacterial load between the 2 groups. Moreover, the bacterial targets of early IgA responses (including coating of the Bacteroides genus), as well as IgA recognition patterns, differed between healthy children and children with allergic manifestations. Altered IgA recognition patterns in children with allergy were observed already at 1 month of age, when the IgA antibodies are predominantly maternally derived in breast-fed children. An aberrant IgA responsiveness to the gut microbiota during infancy precedes asthma and allergy development, possibly indicating an impaired mucosal barrier function in allergic children. Copyright © 2016 American Academy of Allergy, Asthma & Immunology. Published by Elsevier Inc. All rights reserved.

  5. TARP Monthly Housing Scorecard

    Data.gov (United States)

    Department of the Treasury — Treasury and the U.S. Department of Housing and Urban Development (HUD) jointly produce a Monthly Housing Scorecard on the health of the nation’s housing market. The...

  6. Lightship Monthly Observations

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Daily Weather Observations (Monthly Form 1001) from lightship stations in the United States. Please see the 'Surface Weather Observations (1001)' library for more...

  7. Oceanographic Monthly Summary

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Oceanographic Monthly Summary contains sea surface temperature (SST) analyses on both regional and ocean basin scales for the Atlantic, Pacific, and Indian Oceans....

  8. Podocyte hypertrophy precedes apoptosis under experimental diabetic conditions.

    Science.gov (United States)

    Lee, Sun Ha; Moon, Sung Jin; Paeng, Jisun; Kang, Hye-Young; Nam, Bo Young; Kim, Seonghun; Kim, Chan Ho; Lee, Mi Jung; Oh, Hyung Jung; Park, Jung Tak; Han, Seung Hyeok; Yoo, Tae-Hyun; Kang, Shin-Wook

    2015-08-01

    Podocyte hypertrophy and apoptosis are two hallmarks of diabetic glomeruli, but the sequence in which these processes occur remains a matter of debate. Here we investigated the effects of inhibiting hypertrophy on apoptosis, and vice versa, in both podocytes and glomeruli, under diabetic conditions. Hypertrophy and apoptosis were inhibited using an epidermal growth factor receptor inhibitor (PKI 166) and a pan-caspase inhibitor (zAsp-DCB), respectively. We observed significant increases in the protein expression of p27, p21, phospho-eukaryotic elongation factor 4E-binding protein 1, and phospho-p70 S6 ribosomal protein kinase, in both cultured podocytes exposed to high-glucose (HG) medium, and streptozotocin-induced diabetes mellitus (DM) rat glomeruli. These increases were significantly inhibited by PKI 166, but not by zAsp-DCB. In addition, the amount of protein per cell, the relative cell size, and the glomerular volume were all significantly increased under diabetic conditions, and these changes were also blocked by treatment with PKI 166, but not zAsp-DCB. Increased protein expression of cleaved caspase-3 and cleaved poly (ADP-ribose) polymerase, together with increased Bax/Bcl-2 ratios, were also observed in HG-stimulated podocytes and DM glomeruli. Treatment with either zAsp-DCB or PKI 166 resulted in a significant attenuation of these effects. Both PKI 166 and zAsp-DCB also inhibited the increase in number of apoptotic cells, as assessed by Hoechst 33342 staining and TUNEL assay. Under diabetic conditions, inhibition of podocyte hypertrophy results in attenuated apoptosis, whereas blocking apoptosis has no effect on podocyte hypertrophy, suggesting that podocyte hypertrophy precedes apoptosis.

  9. Current status of frameless anchored IUD for immediate intracesarean insertion.

    Science.gov (United States)

    Wildemeersch, Dirk; Goldstuck, Norman D; Hasskamp, Thomas

    2016-01-01

    Immediate postpartum intrauterine device (IUD) insertion deserves great attention as it can provide immediate, timely and convenient contraception plus the added benefit of preventing repeat unintended pregnancies. Although women post vaginal delivery can benefit from immediate post-placenta contraception, women undergoing Cesarean section clearly need contraception, as an inter-delivery interval shorter than 18 months places them at a high risk for uterine rupture. The main drawback of currently available framed IUD devices for immediate postpartum insertion of an IUD is their high expulsion and displacement rates when inserted immediately postpartum after both vaginal and Cesarean delivery. Current research suggests that a brief window of opportunity exists of 10 minutes for insertion of conventional IUDs after which time expulsion rates both immediately and over time are greatly enhanced. This paper summarizes the current research conducted to overcome the expulsion problems associated with conventional T-shaped devices as well as through the use of an anchored frameless device. In the 1970s and 1980s, attempts were made to solve the expulsion problem by modifying existing devices, such as adding absorbable sutures (Delta-T) or additional appendages. These attempts proved to be clinically unsuccessful as the catgut suture added to the transverse arms did not provide sufficient resistance to prevent downward displacement and expulsion. An anchoring technique to suspend a copper IUD to the fundus of the uterus was developed in Belgium in the 1980s and has been the subject of extensive ongoing clinical research since 1985. Recently the frameless copper releasing anchor IUD, GyneFix, has been tested for postplacental insertion. Initially, the anchor was modified by the inclusion of a biodegradable cone which was added below the anchoring knot. Clinical studies confirmed the adequacy of this approach suggesting that it was technically possible to anchor an IUD

  10. The feasibility of immediately loading dental implants in edentulous jaws.

    Science.gov (United States)

    Henningsen, Anders; Smeets, Ralf; Wahidi, Aria; Kluwe, Lan; Kornmann, Frank; Heiland, Max; Gerlach, Till

    2016-08-01

    Immediate loading of dental implants has been proved to be feasible in partially edentulous jaws. The purpose of this retrospective investigation was to assess the feasibility of immediately loading dental implants in fully edentulous jaws. A total of 24 patients aged between 53 and 89 years received a total of 154 implants in their edentulous maxillae or mandibles. Among the implants, 45 were set in fresh extracted sockets and 109 in consolidated alveolar bones. The implants were provisionally managed with chair-side made provisional resin bridges and exposed to immediate loading. Implants were followed up for 1-8 years, including radiographic imaging. Marginal bone levels were evaluated based on radiographic imaging. A total of 148 out of the 154 implants survived over the follow-up period of 1 to 8 years, giving a survival rate of 96%. The time or region of the implantation, the pre-implant augmentation, and the length and diameter of the implants had no statistically significant influence on the survival or the success rate. The marginal bone level remained stable with only minimal loss of 0.3 mm after 60 months of loading. Within the limitations of this study, immediate loading is feasible for dental implants in edentulous jaws.

  11. Similar and Contrasting Response of Rifting and Transtension in the Gulf of California and Walker Lane to Preceding Arc Magmatism

    Science.gov (United States)

    Henry, C. D.; Faulds, J. E.

    2006-12-01

    The Gulf of California (GC) and Walker Lane (WL) have undergone strikingly similar development with strike- slip faulting following initial extension. They differ significantly in the amount of Pacific-North American plate motion taken up by each: essentially all relative motion in the GC and ~25% in the WL. In both areas, ancestral arc magmatism preceded and probably focused deformation, perhaps because heating and/or hydration weakened the lithosphere. However, differences in migration of the Rivera (RTJ) and Mendocino triple junctions (MTJ) related to differences in the orientation of plate boundaries determined how strike-slip faulting developed. Abrupt southward jumps in the RTJ led to abrupt cessation of magmatism over arc lengths of as much as 1000 km and initiation of east-northeast extension within the future GC. The best known jump was at ~13 Ma, but an earlier jump occurred at ~18 Ma. Arc magmatism has been best documented in Baja California, Sonora, and Nayarit, although Baja constituted the most-trenchward fringe of the ancestral arc. New and published data indicate that Sinaloa underwent a similar history of arc magmatism. The greatest volume of the arc immediately preceding RTJ jumps was probably in mainland Mexico. Arc magmatism shut off following these jumps, extension began in the future GC, and strike-slip faulting either followed or accompanied extension in the GC. In contrast, the MTJ migrated progressively northward. New and published data indicate magmatism generally shut off coincident with this retreat, but distinct nodes or zones of magmatism, presumably unrelated to subduction, persisted or initiated after arc activity ceased. We have suggested that the WL has grown progressively northward, following the retreating arc, and that the northern WL is its youngest part. However, the timing of initiation of strike-slip faulting in most of the WL is poorly known and controversial. Testing our hypothesis requires determining initiation and

  12. Immediate error correction process following sleep deprivation

    National Research Council Canada - National Science Library

    HSIEH, SHULAN; CHENG, I‐CHEN; TSAI, LING‐LING

    2007-01-01

    ...) participated in this study. Participants performed a modified letter flanker task and were instructed to make immediate error corrections on detecting performance errors. Event‐related potentials (ERPs...

  13. Forced Aerobic Exercise Preceding Task Practice Improves Motor Recovery Poststroke

    Science.gov (United States)

    Rosenfeldt, Anson B.; Dey, Tanujit; Alberts, Jay L.

    2017-01-01

    OBJECTIVE. To understand how two types of aerobic exercise affect upper-extremity motor recovery post-stroke. Our aims were to (1) evaluate the feasibility of having people who had a stroke complete an aerobic exercise intervention and (2) determine whether forced or voluntary exercise differentially facilitates upper-extremity recovery when paired with task practice. METHOD. Seventeen participants with chronic stroke completed twenty-four 90-min sessions over 8 wk. Aerobic exercise was immediately followed by task practice. Participants were randomized to forced or voluntary aerobic exercise groups or to task practice only. RESULTS. Improvement on the Fugl-Meyer Assessment exceeded the minimal clinically important difference: 12.3, 4.8, and 4.4 for the forced exercise, voluntary exercise, and repetitive task practice–only groups, respectively. Only the forced exercise group exhibited a statistically significant improvement. CONCLUSION. People with chronic stroke can safely complete intensive aerobic exercise. Forced aerobic exercise may be optimal in facilitating motor recovery associated with task practice. PMID:28218596

  14. Menstrual irregularities and lactation failure may precede thyroid dysfunction or goitre.

    Directory of Open Access Journals (Sweden)

    Joshi J

    1993-07-01

    Full Text Available Menstrual and reproductive history of 178 women referred to the thyroid clinic was compared with 49 healthy controls. Cases were classified as euthyroid, hypothyroid or hyperthyroid after clinical examination and after serum T3, T4, TSH measurements. Reproductive history was related chronologically to symptoms and signs of thyroid dysfunction. Only 31.8% of hypothyroid and 35.3% of hyperthyroid women had normal menstrual pattern in contrast with 56.3% of Euthyroid and 87.8% of healthy controls (p < 0.001. Reproductive failure (infertility, pregnancy wastage, failure of lactation occurred in 37.5% of hypothyroid and 36.5% of hyperthyroid cases against 16.3% of euthyroid and 16.7% of healthy controls (p < 0.05. Interestingly, in 45% of cases with menstrual abnormality, the anomaly was antecedent to other clinical features by a variable period of two months to ten years. Reproductive failure and lactation failure also preceded thyroid dysfunction or goitre. Reproductive dysfunction may therefore be considered as one of the presenting symptoms of thyroid disorders in women, keeping in mind both menstrual irregularities and lactation failure may also arise from other common or idiopathic origins. Especially in women with menstrual irregularities in the perimenopausal age if thyroid dysfunction is detected, pharmacotherapy may be a superior alternative to surgical interventions like hysterectomy.

  15. General practice consultations, diagnostic investigations, and prescriptions in the year preceding a lung cancer diagnosis

    DEFF Research Database (Denmark)

    Guldbrandt, Louise M; Møller, Henrik; Jakobsen, Erik;

    2017-01-01

    Patterns of general practice utilization in the period before lung cancer (LC) diagnosis may provide new knowledge to ensure timelier and earlier diagnosis of LC. This study aimed to explore the prediagnostic activity in general practice in the year preceding LC diagnosis. The activity was compared...... = 340,170). During months 12 to 1 prior to diagnosis, 92.6% of LC patients and 88.4% of comparison subjects had one or more contacts with general practice. 13.0% of LC patients and 3.3% of comparison subjects had two or more X-rays. 20.8% of LC patients and 8.5% of comparison subjects had two or more...... than COPD patients without lung cancer, but not as pronounced as compared to patients without COPD. There was a significant increase in healthcare seeking and diagnostic activity in the year prior to a LC diagnosis, regardless of stage at diagnosis. COPD may mask the symptoms of LC. This indicates...

  16. Migratory large vessel vasculitis preceding acute myeloid leukemia: a case report.

    Science.gov (United States)

    Chandratilleke, Dinusha; Anantharajah, Anthea; Vicaretti, Mauro; Benson, Warwick; Berglund, Lucinda J

    2017-03-16

    Large vessel vasculitis is a rare disorder usually occurring in the context of the autoimmune conditions of giant cell arteritis and Takayasu's arteritis. Case reports have described large vessel vasculitis occurring in individuals with myelodysplastic syndrome, preceding transformation to acute myeloid leukemia. A 56-year-old Afghanistan-born woman presented with fever, a tender left carotid artery, and raised inflammatory markers. Computed tomography revealed thickening of the wall of her left carotid artery. Her symptoms resolved spontaneously; however, they recurred weeks later on the contralateral side, along with abdominal pain after eating. Further imaging with computed tomography and positron emission tomography demonstrated resolution of her left carotid artery abnormality, but new wall thickening and inflammation in her right carotid artery, abdominal aorta, and superior mesenteric artery. She was diagnosed as having large vessel vasculitis, which resolved with corticosteroids and methotrexate. Five months later, she developed acute myeloid leukemia. She had no known history of myelodysplastic syndrome at the time of diagnosis with vasculitis. Large vessel vasculitis in older individuals presenting with atypical clinical features, such as a migratory pattern of affected vessels, vessel wall tenderness, and marked systemic inflammation, should prompt a search for underlying myelodysplasia. Clinicians should be vigilant for progression to acute myeloid leukemia.

  17. Monthly energy review

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1997-12-01

    This document presents an overview of the Energy Information Administration`s (EIA) recent monthly energy statistics. The statistics cover the major activities of U.S. production, consumption, trade, stocks, and prices for petroleum, natural gas, coal, electricity, and nuclear energy. Also included are international energy and thermal and metric conversion factors.

  18. Photos of the month

    CERN Multimedia

    Claudia Marcelloni de Oliveira

    Congratulations to Adele Rimoldi, ATLAS physicist from Pavia, who ran her first marathon in New York last month. Adele completed the 42.2 km in a time of 4:49:19. She sure makes it look easy!!! The ATLAS pixel service quarter panel in SR1

  19. Monthly Energy Review

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-05-28

    This publication presents an overview of the Energy information Administration`s recent monthly energy statistics. The statistics cover the major activities of US production, consumption, trade, stocks, and prices for petroleum, natural gas, coal, electricity, and nuclear energy. Also included are international energy and thermal and metric conversion factors. Two brief ``energy plugs`` (reviews of EIA publications) are included, as well.

  20. 26 CFR 1.665(e)-1A - Preceding taxable year.

    Science.gov (United States)

    2010-04-01

    ... 26 Internal Revenue 8 2010-04-01 2010-04-01 false Preceding taxable year. 1.665(e)-1A Section 1... (CONTINUED) INCOME TAXES Treatment of Excess Distributions of Trusts Applicable to Taxable Years Beginning on Or After January 1, 1969 § 1.665(e)-1A Preceding taxable year. (a) Definition—(1) Domestic trusts—(i...

  1. 22 CFR 42.68 - Informal evaluation of family members if principal applicant precedes them.

    Science.gov (United States)

    2010-04-01

    ... 22 Foreign Relations 1 2010-04-01 2010-04-01 false Informal evaluation of family members if principal applicant precedes them. 42.68 Section 42.68 Foreign Relations DEPARTMENT OF STATE VISAS VISAS... Visas § 42.68 Informal evaluation of family members if principal applicant precedes them....

  2. Perspective-Free Pragmatics: Broken Precedents and the Recovery-from-Preemption Hypothesis

    Science.gov (United States)

    Kronmuller, Edmundo; Barr, Dale J.

    2007-01-01

    When speakers refer to the same referent multiple times in a conversation, they tend to follow established patterns of usage, known as "conversational precedents." Research has found that listeners expect speakers to follow precedents, and that this expectation guides their search for referents (Barr, D. J., & Keysar, B. (2002). "Anchoring…

  3. Immediate complications of percutaneous central venous cannulation in children

    Science.gov (United States)

    Dheer, Geetika; Chaudhry, Gurmeet Kaur; Singh, Tejinder

    2011-01-01

    Objective: To study the incidence of immediate complications associated with percutaneous central venous catheterization. Materials and Methods: A total of 103 central venous catheters were inserted in 70 children over a period of 18 months, governed by a uniform protocol. Sixty-three percent of the catheters were inserted in neonates, 23.3% in infants and 13.6% in children between 1 and 12 years of age. Statistical Analysis Used: Software SPSS version 15. Results: There were a total of 41 insertion-related immediate complications, of which 75.6% were in neonates. Neonatal age, hemodynamic instability and more number of attempts to catheterize the vein had a higher risk of insertion-related problems. There was no mortality directly as a result of the procedure. Conclusion: In our practice, it was observed that complications were fewer with increasing familiarity with the procedure. Hence, percutaneous central venous catheterization is a safe procedure when performed in experienced hands. PMID:22121313

  4. Immediate complications of percutaneous central venous cannulation in children

    Directory of Open Access Journals (Sweden)

    Geetika Dheer

    2011-01-01

    Full Text Available Objective: To study the incidence of immediate complications associated with percutaneous central venous catheterization. Materials and Methods: A total of 103 central venous catheters were inserted in 70 children over a period of 18 months, governed by a uniform protocol. Sixty-three percent of the catheters were inserted in neonates, 23.3% in infants and 13.6% in children between 1 and 12 years of age. Statistical Analysis Used: Software SPSS version 15. Results: There were a total of 41 insertion-related immediate complications, of which 75.6% were in neonates. Neonatal age, hemodynamic instability and more number of attempts to catheterize the vein had a higher risk of insertion-related problems. There was no mortality directly as a result of the procedure. Conclusion: In our practice, it was observed that complications were fewer with increasing familiarity with the procedure. Hence, percutaneous central venous catheterization is a safe procedure when performed in experienced hands.

  5. A synthesis of radial growth patterns preceding tree mortality

    Science.gov (United States)

    Cailleret, Maxime; Jansen, Steven; Robert, Elisabeth M.R.; Desoto, Lucia; Aakala, Tuomas; Antos, Joseph A.; Beikircher, Barbara; Bigler, Christof; Bugmann, Harald; Caccianiga, Marco; Cada, Vojtech; Camarero, Jesus J.; Cherubini, Paolo; Cochard, Herve; Coyea, Marie R.; Cufar, Katarina; Das, Adrian J.; Davi, Hendrik; Delzon, Sylvain; Dorman, Michael; Gea-Izquierdo, Guillermo; Gillner, Sten; Haavik, Laurel J.; Hartmann, Henrik; Heres, Ana-Maria; Hultine, Kevin R.; Janda, Pavel; Kane, Jeffrey M.; Kharuk, Vyacheslav I.; Kitzberger, Thomas; Klein, Tamir; Kramer, Koen; Lens, Frederic; Levanic, Tom; Calderon, Juan C. Linares; Lloret, Francisco; Lobo-Do-Vale, Raquel; Lombardi, Fabio; Lopez Rodriguez, Rosana; Makinen, Harri; Mayr, Stefan; Meszaros, IIona; Metsaranta, Juha M.; Minunno, Francesco; Oberhuber, Walter; Papadopoulos, Andreas; Peltoniemi, Mikko; Petritan, Any M.; Rohner, Brigitte; Sanguesa-Barreda, Gabriel; Sarris, Dimitrios; Smith, Jeremy M.; Stan, Amanda B.; Sterck, Frank; Stojanovic, Dejan B.; Suarez, Maria L.; Svoboda, Miroslav; Tognetti, Roberto; Torres-Ruiz, Jose M.; Trotsiuk, Volodymyr; Villalba, Ricardo; Vodde, Floor; Westwood, Alana R.; Wyckoff, Peter H.; Zafirov, Nikolay; Martinez-Vilalta, Jordi

    2017-01-01

    Tree mortality is a key factor influencing forest functions and dynamics, but our understanding of the mechanisms leading to mortality and the associated changes in tree growth rates are still limited. We compiled a new pan-continental tree-ring width database from sites where both dead and living trees were sampled (2970 dead and 4224 living trees from 190 sites, including 36 species), and compared early and recent growth rates between trees that died and those that survived a given mortality event. We observed a decrease in radial growth before death in ca. 84% of the mortality events. The extent and duration of these reductions were highly variable (1–100 years in 96% of events) due to the complex interactions among study species and the source(s) of mortality. Strong and long-lasting declines were found for gymnosperms, shade- and drought-tolerant species, and trees that died from competition. Angiosperms and trees that died due to biotic attacks (especially bark-beetles) typically showed relatively small and short-term growth reductions. Our analysis did not highlight any universal trade-off between early growth and tree longevity within a species, although this result may also reflect high variability in sampling design among sites. The intersite and interspecific variability in growth patterns before mortality provides valuable information on the nature of the mortality process, which is consistent with our understanding of the physiological mechanisms leading to mortality. Abrupt changes in growth immediately before death can be associated with generalized hydraulic failure and/or bark-beetle attack, while long-term decrease in growth may be associated with a gradual decline in hydraulic performance coupled with depletion in carbon reserves. Our results imply that growth-based mortality algorithms may be a powerful tool for predicting gymnosperm mortality induced by chronic stress, but not necessarily so for angiosperms and in case of intense drought or

  6. Your Child's Development: 9 Months

    Science.gov (United States)

    ... For Parents MORE ON THIS TOPIC Your Baby's Growth: 9 Months Your Baby's Hearing, Vision, and Other Senses: 9 Months Your Child's Checkup: 9 Months Medical Care and Your 8- to 12-Month-Old Feeding Your 8- to 12-Month-Old Sleep and Your 8- to 12-Month-Old Contact ...

  7. Clinical Evidence for Regenerative Endodontic Procedures: Immediate versus Delayed Induction?

    Science.gov (United States)

    Botero, Tatiana M; Tang, Xianli; Gardner, Richard; Hu, Jan C C; Boynton, James R; Holland, G Rex

    2017-09-01

    Clinicians face many challenges when treating immature permanent teeth in young patients. Immediate blood clot induction can be a successful option as described by some case reports. No experimental studies or clinical trials have addressed this question. We have designed a clinical trial in which we hypothesized that there is no difference in success between immediate or delayed induction protocols. After confirmation of pulpal necrosis, patients were randomized. In the delayed group, 15 teeth were treated following the American Association of Endodontists guidelines, and calcium hydroxide was used as the intracanal medication. In the immediate group, 13 teeth had a blood clot inducted at the first appointment. The teeth were evaluated after 1, 3, and 12 months. Three independent evaluators assessed the periapical healing. The Pearson chi-square test or the Fisher exact test was used to compare the success rates between the 2 groups. Currently, of the 25 recruited patients (28 teeth), 19 have completed their 12-month follow-up. The group with delayed induction had a 71% success rate, and the group with immediate induction had a 33% success rate. In most cases (79%), trauma was the etiology. All successful cases started at stage 9 of root development (Nolla), and the majority showed healing type 2. Determination of the stage of root formation and etiology are possible critical factors for any therapeutic decision. In summary, it is early to conclude or suggest any of the protocols. Clearly, much more data are needed before sample size requirements can be met. Copyright © 2017 American Association of Endodontists. Published by Elsevier Inc. All rights reserved.

  8. Immediate CAD/ CAM Custom Fabricated Dental Implants

    Directory of Open Access Journals (Sweden)

    Jafar Kolahi

    2010-11-01

    Full Text Available Introduction: There will almost always be gaps between cylin-drical or screw shaped prefabricated implant surface and funnel-shaped tooth socket when an implant is placed immediately after tooth extraction. Hence expensive and difficult bone grafting is re-quired. A custom fabricated implant will be a pragmatic solution for this limitation.The hypothesis: First step following extraction of a tooth is data capture or scanning via a 3D scan method e.g. coordinate measuring machine or non-contact laser scanners such as triangulation range finder. Second step is reconstruction or modeling via editable CAD (computer-aided design model, allowing us to add retentive holes and correction of implant angle. Third step is fabrication via CAM (computer aided manufacturing followed by plasma cleaning process. Fourth step is insertion of the CAD/CAM custom fabricated one-stage implant in the fresh tooth socket. Optimal time for this step is 24-48 hours after extraction. The custom fabricated implant should not load 3-4 months. Usage of chlorhexidine mouth-rinse or chewing gum twice daily for 2 weeks and, in some cases oral antibiotic is recommended. Evaluation of the hypothesis: Contemporary dental implant system faced with several clinical and anatomical limitations such is low sinuses or nerve bundles. Complex and expensive surgical procedures such as nerve repositioning and sinus lift are frequently required. With custom fabricated implant we can overcome several of these limitations because insertion of custom fabricated implant will perform before alveolar bone recession.

  9. Immediate Implants: Clinical Guidelines for Esthetic Outcomes

    Directory of Open Access Journals (Sweden)

    Mohammad A. Javaid

    2016-06-01

    Full Text Available Research has shown that tooth loss results in morphological changes in alveolar ridge that may influence the subsequent implant placement. Immediate implant placement was introduced as a possible means to limit bone resorption and reduce the number of surgical procedures following tooth extraction. Histological and clinical evidence from human clinical studies showing efficacy of immediate implants has come to light over the last decade or so. However, immediate implant placement is a challenging surgical procedure and requires proper case selection and surgical technique. Furthermore, there appears to be a lack of clinical guidelines for immediate implant placement case selection. Therefore, the aim of this mini-review is to analyze critical evidence from human studies in order to establish clinical guidelines which may help clinicians in case selection when considering immediate implant placement protocol.

  10. Petroleum marketing monthly

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-07-01

    Petroleum Marketing Monthly (PPM) provides information and statistical data on a variety of crude oils and refined petroleum products. The publication presents statistics on crude oil costs and refined petroleum products sales for use by industry, government, private sector analysts, educational institutions, and consumers. Data on crude oil include the domestic first purchase price, the f.o. b. and landed cost of imported crude oil, and the refiners` acquisition cost of crude oil. Refined petroleum product sales data include motor gasoline, distillates, residuals, aviation fuels, kerosene, and propane. The Petroleum Marketing Division, Office of Oil and Gas, Energy Information Administration ensures the accuracy, quality, and confidentiality of the published data in the Petroleum Marketing Monthly.

  11. Petroleum marketing monthly

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-02-01

    The Petroleum Marketing Monthly (PMM) provides information and statistical data on a variety of crude oils and refined petroleum products. The publication presents statistics on crude oil costs and refined petroleum products sales for use by industry, government, private sector analysts, educational institutions, and consumers. Data on crude oil include the domestic first purchase price, the f.o.b. and landed cost of imported crude oil, and the refiners acquisition cost of crude oil. Refined petroleum product sales data include motor gasoline, distillates, residuals, aviation fuels, kerosene, and propane. The Petroleum Marketing Division, Office of Oil and Gas, Energy Information Administration ensures the accuracy, quality, and confidentiality of the published data in the Petroleum Marketing Monthly.

  12. Electric power monthly

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1995-08-01

    The Energy Information Administration (EIA) prepares the Electric Power Monthly (EPM) for a wide audience including Congress, Federal and State agencies, the electric utility industry, and the general public. This publication provides monthly statistics for net generation, fossil fuel consumption and stocks, quantity and quality of fossil fuels, cost of fossil fuels, electricity sales, revenue, and average revenue per kilowatthour of electricity sold. Data on net generation, fuel consumption, fuel stocks, quantity and cost of fossil fuels are also displayed for the North American Electric Reliability Council (NERC) regions. The EIA publishes statistics in the EPM on net generation by energy source, consumption, stocks, quantity, quality, and cost of fossil fuels; and capability of new generating units by company and plant. The purpose of this publication is to provide energy decisionmakers with accurate and timely information that may be used in forming various perspectives on electric issues that lie ahead.

  13. Electric power monthly

    Energy Technology Data Exchange (ETDEWEB)

    Smith, Sandra R.; Johnson, Melvin; McClevey, Kenneth; Calopedis, Stephen; Bolden, Deborah

    1992-05-01

    The Electric Power Monthly is prepared by the Survey Management Division; Office of Coal, Nuclear, Electric and Alternate Fuels, Energy Information Administration (EIA), Department of Energy. This publication provides monthly statistics at the national, Census division, and State levels for net generation, fuel consumption, fuel stocks, quantity and quality of fuel, cost of fuel, electricity sales, revenue, and average revenue per kilowatthour of electricity sold. Data on net generation, fuel consumption, fuel stocks, quantity and cost of fuel are also displayed for the North American Electric Reliability Council (NERC) regions. Additionally, statistics by company and plant are published in the EPM on capability of new plants, new generation, fuel consumption, fuel stocks, quantity and quality of fuel, and cost of fuel.

  14. The first film presentation of REM sleep behavior disorder precedes its scientific debut by 35 years

    Directory of Open Access Journals (Sweden)

    Janković Slavko M.

    2006-01-01

    in a barn, clumsy and goofy dog Bruno is, as dogs usually do, lying on a mat deeply asleep and obviously dreaming of his enemy cat Lucifer. This is clearly implied by a preceding scene showing Lucifer being extremely frightened while observing the dreaming dog in action. The cat Lucifer is instantly aware that the dog is chasing him in a dream and is horrified (Pictures 1-3. In a film sequence lasting only 16 seconds, we see Cinderella being aware that Bruno is firmly asleep, apparently having a terrible dream. While lying on the ground with total absence of any muscle atonia, the dog Bruno chases the cat Lucifer in his dream. He is running and barking, and when in his dream he catches Lucifer, he tries to devour the cat. Cinderella tries to wake him up by calling his name twice, first gently and then more vigorously, as she becomes aware of the content of Lucifer’s dream and his intention. The dog is deeply asleep and does not awake in spite of being exposed to sunlight through the opening door of the barn, and called by name by Cinderella (Pictures 4-14. For such a behavior he is reprimanded by Cinderella who definitely recognized the content of his dream (Pictures 15-36. Immediately upon awakening, Bruno shows his good natured temper and amiable character (Pictures 37-40. The film shows that the producer (Walt Disney and film directors (Wilfred Jackson, Clyde Geronimi and Hamilton Luske were obviously aware that a dog might enact the content of a dream. It also implies that their observation from day-to-day (better to say night-to-night life of the dream enactment is not a rare phenomenon, and that it deserves to be shown in the film. These authors were also aware that dogs having RBD were good-natured during wakefulness and that only in dreams they showed unrestrained aggression; while awake, dog Bruno was only an opponent or enemy to the cat Lucifer, but in dreams the animosity grew to aggression. Disney noticed this peculiar kind of sleep behavior and most

  15. [The first film presentation of REM sleep behavior disorder precedes its scientific debut by 35 years].

    Science.gov (United States)

    Janković, Slavko M; Sokić, Dragoslav V; Vojvodić, Nikola M; Ristić, Aleksandar J

    2006-01-01

    usually do, lying on a mat deeply asleep and obviously dreaming of his enemy cat Lucifer. This is clearly implied by a preceding scene showing Lucifer being extremely frightened while observing the dreaming dog in action. The cat Lucifer is instantly aware that the dog is chasing him in a dream and is horrified (Pictures 1-3). In a film sequence lasting only 16 seconds, we see Cinderella being aware that Bruno is firmly asleep, apparently having a terrible dream. While lying on the ground with total absence of any muscle atonia, the dog Bruno chases the cat Lucifer in his dream. He is running and barking, and when in his dream he catches Lucifer, he tries to devour the cat. Cinderella tries to wake him up by calling his name twice, first gently and then more vigorously, as she becomes aware of the content of Lucifer's dream and his intention. The dog is deeply asleep and does not awake in spite of being exposed to sunlight through the opening door of the barn, and called by name by Cinderella (Pictures 4-14). For such a behavior he is reprimanded by Cinderella who definitely recognized the content of his dream (Pictures 15-36). Immediately upon awakening, Bruno shows his good natured temper and amiable character (Pictures 37-40). The film shows that the producer (Walt Disney) and film directors (Wilfred Jackson, Clyde Geronimi and Hamilton Luske) were obviously aware that a dog might enact the content of a dream. It also implies that their observation from day-to-day (better to say night-to-night) life of the dream enactment is not a rare phenomenon, and that it deserves to be shown in the film. These authors were also aware that dogs having RBD were good-natured during wakefulness and that only in dreams they showed unrestrained aggression; while awake, dog Bruno was only an opponent or enemy to the cat Lucifer, but in dreams the animosity grew to aggression. Disney noticed this peculiar kind of sleep behavior and most probably was aware of its frequency and importance

  16. Cognitive Impairments Preceding and Outlasting Autoimmune Limbic Encephalitis

    Directory of Open Access Journals (Sweden)

    Robert Gross

    2016-01-01

    Full Text Available Mild cognitive impairment (MCI can be the initial manifestation of autoimmune limbic encephalitis (ALE, a disorder that at times presents a diagnostic challenge. In addition to memory impairment, clinical features that might suggest this disorder include personality changes, agitation, insomnia, alterations of consciousness, and seizures. Once recognized, ALE typically responds to treatment with immune therapies, but long-term cognitive deficits may remain. We report two cases of patients with MCI who were ultimately diagnosed with ALE with antibodies against the voltage gated potassium channel complex. Months after apparent resolution of their encephalitides, both underwent neuropsychological testing, which demonstrated persistent cognitive deficits, primarily in the domains of memory and executive function, for cases 1 and 2, respectively. A brief review of the literature is included.

  17. Immediate start of hormonal contraceptives for contraception.

    Science.gov (United States)

    Lopez, Laureen M; Newmann, Sara J; Grimes, David A; Nanda, Kavita; Schulz, Kenneth F

    2012-12-12

    Health care providers often tell women to wait until the next menses to begin hormonal contraception. The intent is to avoid contraceptive use during an undetected pregnancy. An alternative is to start hormonal contraception immediately with back-up birth control for the first seven days. Immediate initiation was introduced with combined oral contraceptives (COCs), and has expanded to other hormonal contraceptives. At the time of the initial review, how immediate start compared to conventional menses-dependent start was unclear regarding effectiveness, continuation, and acceptability. The immediate-start approach may improve women's access to, and continuation of, hormonal contraception. This review examined randomized controlled trials (RCTs) of immediate-start hormonal contraception for differences in effectiveness, continuation, and acceptability. In August 2012, we searched MEDLINE, CENTRAL, POPLINE, LILACS, ClinicalTrials.gov, and ICTRP for trials of immediate-start hormonal contraceptives. We contacted researchers to find other studies. Earlier searches also included EMBASE. We included RCTs that compared immediate start to conventional start of hormonal contraception. Also included were trials that compared immediate start of different hormonal contraceptive methods with each other. Data were abstracted by two authors and entered into RevMan. The Peto odds ratio (OR) with 95% confidence interval (CI) was calculated. Five studies were included. No new eligible studies have been found since the review was initially conducted. Method discontinuation was similar between groups in all trials. Bleeding patterns and side effects were similar in trials that compared immediate with conventional start. In a study of depot medroxyprogesterone acetate (DMPA), immediate start of DMPA showed fewer pregnancies than a 'bridge' method before DMPA (OR 0.36; 95% CI 0.16 to 0.84). Further, more women in the immediate-DMPA group were very satisfied versus those with a 'bridge

  18. Immediate versus delayed postpartum use of levonorgestrel contraceptive implants: a randomized controlled trial in Uganda.

    Science.gov (United States)

    Averbach, Sarah; Kakaire, Othman; Kayiga, Herbert; Lester, Felicia; Sokoloff, Abby; Byamugisha, Josaphat; Dehlendorf, Christine; Steinauer, Jody

    2017-06-10

    Use of long-acting, highly effective contraception has the potential to improve women's ability to avoid short interpregnancy intervals, which are associated with an increased risk of maternal morbidity and mortality, and preterm delivery. In Uganda, contraceptive implants are not routinely available during the immediate postpartum period. The purpose of this study was to compare the proportion of women using levonorgestrel contraceptive implants at 6 months after delivery in women randomized to immediate or delayed insertion. This was a randomized controlled trial among women in Kampala, Uganda. Women who desired contraceptive implants were randomly assigned to insertion of a 2-rod contraceptive implant system containing 75 mg of levonorgestrel immediately following delivery (within 5 days of delivery and before discharge from the hospital) or delayed insertion (6 weeks postpartum). The primary outcome was implant utilization at 6 months postpartum. From June to October 2015, 205 women were randomized, 103 to the immediate group and 102 to the delayed group. Ninety-three percent completed the 6 month follow-up visit. At 6 months, implant use was higher in the immediate group compared with the delayed group (97% vs 68%; P < .001), as was the use of any highly effective contraceptive (98% vs 81%; P = .001). Women in the immediate group were more satisfied with the timing of implant placement. If given the choice, 81% of women in the immediate group and 63% of women in the delayed group would choose the same timing of placement again (P = .01). There were no serious adverse events in either group. Offering women the option of initiating contraceptive implants in the immediate postpartum period has the potential to increase contraceptive utilization, decrease unwanted pregnancies, prevent short interpregnancy intervals, and help women achieve their reproductive goals. Copyright © 2017 Elsevier Inc. All rights reserved.

  19. Survival of immediately versus delayed loaded short implants: a prospective case series study

    OpenAIRE

    Alvira González, Joaquín; Díaz Campos, Erick; Sánchez Garcés, María Angeles; Gay Escoda, Cosme

    2015-01-01

    Background To assess and compare survival rates of immediately and delayed loaded short implants (7 mm) in free ends of a partially edentulous jaw with moderate-severe alveolar bone resorption. Material and Methods 24 patients with atrophic edentulous free-ends were included in this prospective study. Four study groups were monitored monthly and their behavior was evaluated: bridges supported only by short implants and mixed short and long implant bridge groups, both with immediate and delaye...

  20. Petroleum marketing monthly

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1995-11-01

    The Petroleum Marketing Monthly (PMM) provides information and statistical data on a variety of crude oils and refined petroleum products. The publication presents statistics on crude oil costs and refined petroleum products sales for use by industry, government, private sector analysts, educational institutions, and consumers. Data on crude oil include the domestic first purchase price, the f.o.b. and landed cost of imported crude oil, and the refiners` acquisition cost of crude oil. Refined petroleum product sales data include motor gasoline, distillates, residuals, aviation fuels, kerosene, and propane. The Petroleum Marketing Division, Office of Oil and Gas, Energy Information Administration ensures the accuracy, quality, and confidentiality of the published data.

  1. Immediate Intrauterine Device Insertion Following Surgical Abortion.

    Science.gov (United States)

    Patil, Eva; Bednarek, Paula H

    2015-12-01

    Placement of an intrauterine device (IUD) immediately after a first or second trimester surgical abortion is safe and convenient and decreases the risk of repeat unintended pregnancy. Immediate postabortion IUD placement is not recommended in the setting of postprocedure hemorrhage, uterine perforation, infection, or hematometra. Otherwise, there are few contraindications to IUD placement following surgical abortion. Sexually transmitted infection screening should follow US Centers for Disease Control and Prevention guidelines. No additional antibiotics are needed beyond those used for the abortion. Placing immediate postabortion IUDs makes highly-effective long-acting reversible contraception more accessible to women.

  2. Influence of a preceding auditory stimulus on evoked potential of the succeeding stimulus

    Institute of Scientific and Technical Information of China (English)

    WANG Mingshi; LIU Zhongguo; ZHU Qiang; LIU Jin; WANG Liqun; LIU Haiying

    2004-01-01

    In the present study, we investigated the influence of the preceding auditory stimulus on the auditory-evoked potential (AEP) of the succeeding stimuli, when the human subjects were presented with a pair of auditory stimuli. We found that the evoked potential of the succeeding stimulus was inhibited completely by the preceding stimulus, as the inter-stimulus interval (ISI) was shorter than 150 ms. This influence was dependent on the ISI of two stimuli, the shorter the ISI the stronger the influence would be. The inhibitory influence of the preceding stimulus might be caused by the neural refractory effect.

  3. Immediate loading of subcrestally placed dental implants in anterior and premolar sites.

    Science.gov (United States)

    Henningsen, Anders; Smeets, Ralf; Köppen, Kai; Sehner, Susanne; Kornmann, Frank; Gröbe, Alexander; Heiland, Max; Gerlach, Till

    2017-08-23

    Immediate loading of dental implants has been evolving into an appropriate procedure for the treatment of partially edentulous jaws. The purpose of this study was to evaluate the clinical success and radiological outcome of immediately and delayed loaded dental implants in anterior and premolar sites. In this retrospective study, data of 163 individuals requiring tooth removal with subsequent implant placement in anterior and premolar sites were analyzed. Implants were immediately loaded by provisional acrylic resin bridges or loaded with delay. Implants were followed up annually for up to 9 years including intraoral radiographs. A total of 285 implants in 163 patients were placed. 218 implants were immediately loaded and 67 implants with delay. Fifteen implants failed during the follow-up period resulting in survival rates of 94.5% for immediate loading and 95.5% for delayed loading. After an initial decrease of 0.3 mm in the first 12 months the marginal bone level remained stable. No statistically significant differences were found in marginal bone loss between immediately and delayed loaded implants (P = 0.518, 95% CI). Within the limits of this study, immediate loading of immediately subcrestally placed dental implants in anterior and premolar sites is a reliable treatment option for dental rehabilitation. Copyright © 2017 European Association for Cranio-Maxillo-Facial Surgery. Published by Elsevier Ltd. All rights reserved.

  4. The correlation of characters of cognitive impairment preceding Alzheimer s dementia in individuals with questionable dementia to Chinese medical syndrome%可疑痴呆人群中阿尔茨海默氏病临床前的认识损害特征及其与中医证候的关系

    Institute of Scientific and Technical Information of China (English)

    田金洲; 杨承芝; 盛彤; 刘桓; JudyHawortb; RomolaBucks; GordonWilcock

    1999-01-01

    To look for predictive markers preceding Alzheimer s dementia. Methods: This study involved multitudinal assessment of individuals in whom there was cognitive impairment that was insufficient to warrant a diagnosis of dementia, which were followed up for mean 11 months. Results: A diagnosis of probable AD was made in 58% of cases, VD in 21%, FLD in 5% and dementia of uncertain aetiology in the remainder. 42% subjects with memory loss are as result of ageassociated cognitive decline, 25% subjects are due to cerebralvascular accident, 1.8% subjects due to menopausal symptoms. 30.4% are of memory loss of unknown aetiology. Cognitive markers preceding dementia found within this study actually have discriminant function of the earliest changes of AD from age-associated cognitive decline. The group that developed dementia on follow-up does not differ significantly from the memory loss group on the WAIS-R total scores or on the digit forward, digit backward and picture completion. However, the subtest score for similarities on the WAIS-R is significantly lower in patients who became demented comparing with the rest of sample. Verbal memory such as story recall immediate and story recall delayed, verbal learning discriminant index, verbal fluency raw score showed significant lower in patients who became dementia. Moreover digit copy transformedscore on the SSRS also is very significantly lower in patients who became demented than those who were stable memory loss. The kidney deficiency syndrome of Chinese medicine was most common in QD, and the phlegm syndrome and the blood stasis syndrome were more common. The scores of the picture completion subtest and the story recall immediate subtest were significantly correlated to the score of the phlegm syndrome respectively. The scores of the picture completion subtest and the similarities subtest were significantly correlated with the score of the kidney deficiency syndrome respectively. Suggestion: Often a significantly long

  5. Commissioners' Monthly Case Activity Report

    Data.gov (United States)

    Occupational Safety and Health Review Commission — Total cases pending at the beginning of the month, total cases added to the docket during the month, total cases disposed of during the month, and total cases...

  6. Dentate gyrus network dysfunctions precede the symptomatic phase in a genetic mouse model of seizures

    Directory of Open Access Journals (Sweden)

    Oana eToader

    2013-08-01

    Full Text Available Neuronal circuit disturbances that lead to hyperexcitability in the cortico-hippocampal network are one of the landmarks of temporal lobe epilepsy. The dentate gyrus (DG network plays an important role in regulating the excitability of the entire hippocampus by filtering and integrating information received via the perforant path. Here, we investigated possible epileptogenic abnormalities in the function of the DG neuronal network in the Synapsin II (Syn II knockout mouse (Syn II-/-, a genetic mouse model of epilepsy. Syn II is a presynaptic protein whose deletion in mice reproducibly leads to generalized seizures starting at the age of two months. We made use of a high-resolution microelectrode array (4096 electrodes and patch-clamp recordings, and found that in acute hippocampal slices of young pre-symptomatic (3-6 weeks-old Syn II-/- mice excitatory synaptic output of the mossy fibers is reduced. Moreover, we showed that the main excitatory neurons present in the polymorphic layer of the DG, hilar mossy cells, display a reduced excitability. We also provide evidence of a predominantly inhibitory regulatory output from mossy cells to granule cells, through feed-forward inhibition, and show that the excitatory-inhibitory ratio is increased in both pre-symptomatic and symptomatic Syn II-/- mice. These results support the key role of the hilar mossy neurons in maintaining the normal excitability of the hippocampal network and show that the late epileptic phenotype of the Syn II-/- mice is preceded by neuronal circuitry dysfunctions. Our data provide new insights into the mechanisms of epileptogenesis in the Syn II-/- mice and open the possibility for early diagnosis and therapeutic interventions.

  7. Management of intrusive luxation with immediate surgical repositioning

    Directory of Open Access Journals (Sweden)

    Mazumdar Dibyendu

    2009-01-01

    Full Text Available Intrusive luxation is one of the most severe forms of traumatic injuries in which the affected tooth is forced to displace deeper into the alveolus. As a consequence of this type of injury, maximum damage occurs to the pulp and all the supporting structures. This report presents a case of severe intrusive luxation of mature maxillary central and lateral incisor in a 40-year-old male. The intruded tooth was immediately repositioned (surgical extrusion and splinted within hours following injury. Antibiotic therapy was initiated at the time of repositioning and maintained for 5 days. Pulp removal and calcium hydroxide treatment of the root canal was carried out after repositioning. Splint was removed 2 months later. Definitive root canal treatment with Gutta percha was accomplished at a later appointment. Clinical and radiographic examination 6, 12 and 24 months after the surgical extrusion revealed satisfactory progressive apical and periodontal healing.

  8. Acute HIV infection detection and immediate treatment estimated to reduce transmission by 89% among men who have sex with men in Bangkok

    Science.gov (United States)

    Kroon, Eugène D.M.B.; Phanuphak, Nittaya; Shattock, Andrew J.; Fletcher, James L.K.; Pinyakorn, Suteeraporn; Chomchey, Nitiya; Akapirat, Siriwat; de Souza, Mark S.; Robb, Merlin L.; Kim, Jerome H.; van Griensven, Frits; Ananworanich, Jintanat; Wilson, David P.

    2017-01-01

    Abstract Introduction: Antiretroviral treatment (ART) reduces HIV transmission. Despite increased ART coverage, incidence remains high among men who have sex with men (MSM) in many places. Acute HIV infection (AHI) is characterized by high viral replication and increased infectiousness. We estimated the feasible reduction in transmission by targeting MSM with AHI for early ART. Methods: We recruited a cohort of 88 MSM with AHI in Bangkok, Thailand, who initiated ART immediately. A risk calculator based on viral load and reported behaviour, calibrated to Thai epidemiological data, was applied to estimate the number of onwards transmissions. This was compared with the expected number without early interventions. Results: Forty of the MSM were in 4th-generation AHI stages 1 and 2 (4thG stage 1, HIV nucleic acid testing (NAT)+/4thG immunoassay (IA)-/3rdG IA–; 4thG stage 2, NAT+/4thG IA+/3rdG IA–) while 48 tested positive on third-generation IA but had negative or indeterminate western blot (4thG stage 3). Mean plasma HIV RNA was 5.62 log10 copies/ml. Any condomless sex in the four months preceding the study was reported by 83.7%, but decreased to 21.2% by 24 weeks on ART. After ART, 48/88 (54.6%) attained HIV RNA HIV transmission occurs during AHI. Diagnosis of AHI with early ART initiation can substantially reduce onwards transmission. PMID:28691441

  9. Exact and Heuristic Algorithms for Routing AGV on Path with Precedence Constraints

    Directory of Open Access Journals (Sweden)

    Liang Xu

    2016-01-01

    Full Text Available A new problem arises when an automated guided vehicle (AGV is dispatched to visit a set of customers, which are usually located along a fixed wire transmitting signal to navigate the AGV. An optimal visiting sequence is desired with the objective of minimizing the total travelling distance (or time. When precedence constraints are restricted on customers, the problem is referred to as traveling salesman problem on path with precedence constraints (TSPP-PC. Whether or not it is NP-complete has no answer in the literature. In this paper, we design dynamic programming for the TSPP-PC, which is the first polynomial-time exact algorithm when the number of precedence constraints is a constant. For the problem with number of precedence constraints, part of the input can be arbitrarily large, so we provide an efficient heuristic based on the exact algorithm.

  10. Historical Uses of Meteoritic Metals as Precedent for Modern In-Situ Asteroid Mining

    Science.gov (United States)

    Krispin, D.; Mardon, A. A.; Fawcett, B. G.

    2016-08-01

    The strain on earth's resources of metal and the metallic density of meteorites mean that in situ asteroid mining is advisable. This has precedent: Use of meteoritic metal dates back to ancient times.

  11. Brain Musics: History, Precedents, and Commentary on Whalley, Mavros and Furniss

    National Research Council Canada - National Science Library

    Miguel Ortiz; Mick Grierson; Atau Tanaka

    2015-01-01

    .... With our commentary, we contextualize the work within the field of Music Neuroscience. Specifically, we point at precedents in EEG-based musical practice as well as ongoing research in the field...

  12. Benchmarking monthly homogenization algorithms

    Directory of Open Access Journals (Sweden)

    V. K. C. Venema

    2011-08-01

    Full Text Available The COST (European Cooperation in Science and Technology Action ES0601: Advances in homogenization methods of climate series: an integrated approach (HOME has executed a blind intercomparison and validation study for monthly homogenization algorithms. Time series of monthly temperature and precipitation were evaluated because of their importance for climate studies and because they represent two important types of statistics (additive and multiplicative. The algorithms were validated against a realistic benchmark dataset. The benchmark contains real inhomogeneous data as well as simulated data with inserted inhomogeneities. Random break-type inhomogeneities were added to the simulated datasets modeled as a Poisson process with normally distributed breakpoint sizes. To approximate real world conditions, breaks were introduced that occur simultaneously in multiple station series within a simulated network of station data. The simulated time series also contained outliers, missing data periods and local station trends. Further, a stochastic nonlinear global (network-wide trend was added.

    Participants provided 25 separate homogenized contributions as part of the blind study as well as 22 additional solutions submitted after the details of the imposed inhomogeneities were revealed. These homogenized datasets were assessed by a number of performance metrics including (i the centered root mean square error relative to the true homogeneous value at various averaging scales, (ii the error in linear trend estimates and (iii traditional contingency skill scores. The metrics were computed both using the individual station series as well as the network average regional series. The performance of the contributions depends significantly on the error metric considered. Contingency scores by themselves are not very informative. Although relative homogenization algorithms typically improve the homogeneity of temperature data, only the best ones improve

  13. Relationship Between the Number of Summer Typhoons Engendered over the Northwest Pacific and South China Sea and Main Climatic Conditions in the Preceding Winter and Spring

    Institute of Scientific and Technical Information of China (English)

    XIAO Ziniu; LIANG Hongli; LI Chongyin

    2010-01-01

    Based on the monthly NCEP/NCAR reanalysis data, OLR (outgoing longwave radiation) data, and tropical cyclone data from the Typhoon Annual and Tropical Cyclone Annual edited by China Meteorological Administration, the relationship between the number of tropical cyclones (with the strongest wind ≥ 17 m s-1, including tropical storm, strong tropical storm, and typhoon, simply called typhoon in this paper) engendered over the Northwest Pacific and South China Sea in summer and the associated climate conditions is studied. First, the characteristics and differences of the climatic conditions between the years with more typhoons and those with fewer typhoons are compared. The results show that the summer typhoon has a close relationship with SST (sea surface temperature) and ITCZ (intertropical convergence zone) anomalies in the preceding winter and spring. With a La Nina like SST anomaly (SSTA) pattern in the preceding winter and spring, the ITCZ will move northwestward and be enhanced around 160°E in the equatorial central Pacific from the preceding winter to spring. The activity of the Pacific ITCZ is in general stronger and its location is more northward than usual, especially in the typhoon genesis region in West Pacific. This background is propitious to have more typhoons in summer. On the other hand, an El Nino like SSTA pattern in the preceding winter will be companied with weaker ITCZ activities, and its location is more southward over the equatorial western Pacific from the preceding winter to spring; this background is propitious to have fewer typhoons in summer. In the year with more typhoons, the warm SST over West Pacific in the preceding winter provides a favorable condition for typhoon fromation in the following summer. It enhances the convergence in the troposphere and increases the water vapor supply to the warm SST region. In the following spring, the perturbation of the tropical ITCZ plays a more important role. When the ITCZ moves northward in

  14. Effects of Different Preceding Crops on Soil Micro-ecological Environment and Yield of Cucumber

    Institute of Scientific and Technical Information of China (English)

    LIU Shouwei; LIU Shuqin; PAN Kai; WANG Lili; WU Fengzhi

    2011-01-01

    Pepper, celery, eggplant and tomato were used as preceding crops to study their effects on the yield, soil microorganism quantity and soil enzyme activities of cucumber. Results showed that four preceding crops all increased soil microorganism quantity in cucumber, but decreased population of Fusarium oxysporum. The effect of pepper was more significant than that of the others Populations of soil bacteria, fungi and actinomyces of pepper treatment were significantly higher than those of the other treatments, except that the populations of fungi had no significant difference with celery and eggplant treatments on 50 days after transplanting, while that of Fusarium oxysporum was fewer than that of the other treatments. The soil microorganism quantity in celery and eggplant treatment was more significant than tomato, but lower population of Fusarium oxysporum. Four preceding crops all increased sol enzyme activities, lnvertase and urease activities of pepper treatment were significantly higher than those of the other treatments, catalase activities of pepper, celery and eggplant treatments were significantly higher than those of tomato and the control treatments All preceding crops remarkably increased cucumber yield, with pepper as the highest. Comparing with the control, cucumber yields of pepper, celery and eggplant treatments increased by 24.9%, 13.6% and 11.9%, respectively. Results suggested that four preceding crops all improved soil microbial ecology and increased cucumber yield. The pepper was the most suitable preceding crop, then followed by celery and eggplant. Tomato had the similar effect as the control.

  15. An improved car-following model with two preceding cars' average speed

    Science.gov (United States)

    Yu, Shao-Wei; Shi, Zhong-Ke

    2015-01-01

    To better describe cooperative car-following behaviors under intelligent transportation circumstances and increase roadway traffic mobility, the data of three successive following cars at a signalized intersection of Jinan in China were obtained and employed to explore the linkage between two preceding cars' average speed and car-following behaviors. The results indicate that two preceding cars' average velocity has significant effects on the following car's motion. Then an improved car-following model considering two preceding cars' average velocity was proposed and calibrated based on full velocity difference model and some numerical simulations were carried out to study how two preceding cars' average speed affected the starting process and the traffic flow evolution process with an initial small disturbance, the results indicate that the improved car-following model can qualitatively describe the impacts of two preceding cars' average velocity on traffic flow and that taking two preceding cars' average velocity into account in designing the control strategy for the cooperative adaptive cruise control system can improve the stability of traffic flow, suppress the appearance of traffic jams and increase the capacity of signalized intersections.

  16. Jogando com os precedentes: regras, analogias, princípios Playing with precedents: rules, analogies, principles

    Directory of Open Access Journals (Sweden)

    Antonio Moreira Maués

    2012-12-01

    Full Text Available Este artigo analisa decisões recentes do STF envolvendo a aplicação de súmulas vinculantes à luz de três concepções de precedentes, desenvolvidas por F. Schauer (precedentes como regras, C. Sunstein (precedentes como analogias e R. Dworkin (precedentes como princípios. Após a exposição dos principais aspectos de cada uma dessas teorias baseadas, respectivamente, nos conceitos de generalizações enraizadas, acordos teóricos incompletos e romance em cadeia, e discute os fundamentos que elas podem oferecer para o uso de precedentes no direito brasileiro.This article analyses the use of binding precedents by the Brazilian Supreme Court in the light of three conceptions of precedents, which are developed by F. Schauer (precedents as rules, C. Sunstein (precedents as analogies and R. Dworkin (precedents as principles. After the exposition of the main aspects of each theory, based respectively on the concepts of entrenched generalizations, incompletely theorized agreements and chain novel, the article debates the arguments that they can provide for the use of precedents in Brazilian law.

  17. Petroleum supply monthly

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1995-10-01

    The Petroleum Supply Monthly (PSM) is one of a family of four publications produced by the Petroleum Supply Division within the Energy Information Administration (EIA) reflecting different levels of data timeliness and completeness. The other publications are the Weekly Petroleum Status Report (WPSR), the Winter Fuels Report, and the Petroleum Supply Annual (PSA). Data presented in the PSM describe the supply and disposition of petroleum products in the United States and major US geographic regions. The data series describe production, imports and exports, inter-Petroleum Administration for Defense (PAD) District movements, and inventories by the primary suppliers of petroleum products in the United States (50 States and the District of Columbia). The reporting universe includes those petroleum sectors in primary supply. Included are: petroleum refiners, motor gasoline blends, operators of natural gas processing plants and fractionators, inter-PAD transporters, importers, and major inventory holders of petroleum products and crude oil. When aggregated, the data reported by these sectors approximately represent the consumption of petroleum products in the United States.

  18. Petroleum Supply Monthly

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-02-01

    The Petroleum Supply Monthly (PSM) is one of a family of four publications produced by the Petroleum Supply Division within the Energy Information Administration (EIA) reflecting different levels of data timeliness and completeness. The other publications are the Weekly Petroleum Status Report (WPSR), the Winter Fuels Report, and the Petroleum Supply Annual (PSA). Data presented in the PSM describe the supply and disposition of petroleum products in the United States and major U.S. geographic regions. The data series describe production, imports and exports, inter-Petroleum Administration for Defense (PAD) District movements, and inventories by the primary suppliers of petroleum products in the United States (50 States and the District of Columbia). The reporting universe includes those petroleum sectors in primary supply. Included are: petroleum refiners, motor gasoline blenders, operators of natural gas processing plants and fractionators, inter-PAD transporters, importers, and major inventory holders of petroleum products and crude oil. When aggregated, the data reported by these sectors approximately represent the consumption of petroleum products in the United States. Data presented in the PSM are divided into two sections: Summary Statistics and Detailed Statistics.

  19. COSMIC monthly progress report

    Science.gov (United States)

    1994-01-01

    Activities of the Computer Software Management and Information Center (COSMIC) are summarized for the month of May 1994. Tables showing the current inventory of programs available from COSMIC are presented and program processing and evaluation activities are summarized. Nine articles were prepared for publication in the NASA Tech Brief Journal. These articles (included in this report) describe the following software items: (1) WFI - Windowing System for Test and Simulation; (2) HZETRN - A Free Space Radiation Transport and Shielding Program; (3) COMGEN-BEM - Composite Model Generation-Boundary Element Method; (4) IDDS - Interactive Data Display System; (5) CET93/PC - Chemical Equilibrium with Transport Properties, 1993; (6) SDVIC - Sub-pixel Digital Video Image Correlation; (7) TRASYS - Thermal Radiation Analyzer System (HP9000 Series 700/800 Version without NASADIG); (8) NASADIG - NASA Device Independent Graphics Library, Version 6.0 (VAX VMS Version); and (9) NASADIG - NASA Device Independent Graphics Library, Version 6.0 (UNIX Version). Activities in the areas of marketing, customer service, benefits identification, maintenance and support, and dissemination are also described along with a budget summary.

  20. Categorizing with Gender: Does Implicit Grammatical Gender Affect Semantic Processing in 24-Month-Old Toddlers?

    Science.gov (United States)

    Bobb, Susan C.; Mani, Nivedita

    2013-01-01

    The current study investigated the interaction of implicit grammatical gender and semantic category knowledge during object identification. German-learning toddlers (24-month-olds) were presented with picture pairs and heard a noun (without a preceding article) labeling one of the pictures. Labels for target and distracter images either matched or…

  1. A case of herpes zoster ophthalmicus preceded one week by diplopia and ophthalmalgia.

    Science.gov (United States)

    Ota, Tomohiro; Yamazaki, Mineo; Toda, Yusuke; Ozawa, Akiko; Kimura, Kazumi

    2017-04-28

    A 66-year-old man presented with headache and ophthalmalgia. Diplopia developed, and he was hospitalized. The left eye had abducent paralysis and proptosis. We diagnosed him with Tolosa-Hunt syndrome and administered methylprednisolone at 1 g/day for 3 days. However, the patient did not respond to treatment. No abnormality was found on his MRI or cerebrospinal fluid examination. Tests showed his serum immunoglobulin G4 and antineutrophil cytoplasmic antibody titers were within normal limits. He also had untreated diabetes mellitus (HbA1c 9.2). One week after first presenting with symptoms, herpes zoster appeared on the patient's dorsum nasi, followed by keratitis and a corneal ulcer. Herpes zoster ophthalmicus with ophthalmoplegia was diagnosed. We began treatment with acyclovir (15 mg/kg) and prednisolone (1 mg/kg, decreased gradually). Ophthalmalgia and the eruption improved immediately. The eye movement disorder improved gradually over several months. It is rare that diplopia appears prior to cingulate eruption of herpes zoster ophthalmicus. We speculated that onset of the eruption was inhibited by strong steroid therapy and untreated diabetes mellitus.

  2. Decadal to monthly timescales of magma transfer and reservoir growth at a caldera volcano.

    Science.gov (United States)

    Druitt, T H; Costa, F; Deloule, E; Dungan, M; Scaillet, B

    2012-02-01

    Caldera-forming volcanic eruptions are low-frequency, high-impact events capable of discharging tens to thousands of cubic kilometres of magma explosively on timescales of hours to days, with devastating effects on local and global scales. Because no such eruption has been monitored during its long build-up phase, the precursor phenomena are not well understood. Geophysical signals obtained during recent episodes of unrest at calderas such as Yellowstone, USA, and Campi Flegrei, Italy, are difficult to interpret, and the conditions necessary for large eruptions are poorly constrained. Here we present a study of pre-eruptive magmatic processes and their timescales using chemically zoned crystals from the 'Minoan' caldera-forming eruption of Santorini volcano, Greece, which occurred in the late 1600s BC. The results provide insights into how rapidly large silicic systems may pass from a quiescent state to one on the edge of eruption. Despite the large volume of erupted magma (40-60 cubic kilometres), and the 18,000-year gestation period between the Minoan eruption and the previous major eruption, most crystals in the Minoan magma record processes that occurred less than about 100 years before the eruption. Recharge of the magma reservoir by large volumes of silicic magma (and some mafic magma) occurred during the century before eruption, and mixing between different silicic magma batches was still taking place during the final months. Final assembly of large silicic magma reservoirs may occur on timescales that are geologically very short by comparison with the preceding repose period, with major growth phases immediately before eruption. These observations have implications for the monitoring of long-dormant, but potentially active, caldera systems.

  3. An improved car-following model with multiple preceding cars' velocity fluctuation feedback

    Science.gov (United States)

    Guo, Lantian; Zhao, Xiangmo; Yu, Shaowei; Li, Xiuhai; Shi, Zhongke

    2017-04-01

    In order to explore and evaluate the effects of velocity variation trend of multiple preceding cars used in the Cooperative Adaptive Cruise Control (CACC) strategy on the dynamic characteristic, fuel economy and emission of the corresponding traffic flow, we conduct a study as follows: firstly, with the real-time car-following (CF) data, the close relationship between multiple preceding cars' velocity fluctuation feedback and the host car's behaviors is explored, the evaluation results clearly show that multiple preceding cars' velocity fluctuation with different time window-width are highly correlated to the host car's acceleration/deceleration. Then, a microscopic traffic flow model is proposed to evaluate the effects of multiple preceding cars' velocity fluctuation feedback in the CACC strategy on the traffic flow evolution process. Finally, numerical simulations on fuel economy and exhaust emission of the traffic flow are also implemented by utilizing VT-micro model. Simulation results prove that considering multiple preceding cars' velocity fluctuation feedback in the control strategy of the CACC system can improve roadway traffic mobility, fuel economy and exhaust emission performance.

  4. Error-preceding brain activity reflects (mal-)adaptive adjustments of cognitive control: a modeling study.

    Science.gov (United States)

    Steinhauser, Marco; Eichele, Heike; Juvodden, Hilde T; Huster, Rene J; Ullsperger, Markus; Eichele, Tom

    2012-01-01

    Errors in choice tasks are preceded by gradual changes in brain activity presumably related to fluctuations in cognitive control that promote the occurrence of errors. In the present paper, we use connectionist modeling to explore the hypothesis that these fluctuations reflect (mal-)adaptive adjustments of cognitive control. We considered ERP data from a study in which the probability of conflict in an Eriksen-flanker task was manipulated in sub-blocks of trials. Errors in these data were preceded by a gradual decline of N2 amplitude. After fitting a connectionist model of conflict adaptation to the data, we analyzed simulated N2 amplitude, simulated response times (RTs), and stimulus history preceding errors in the model, and found that the model produced the same pattern as obtained in the empirical data. Moreover, this pattern is not found in alternative models in which cognitive control varies randomly or in an oscillating manner. Our simulations suggest that the decline of N2 amplitude preceding errors reflects an increasing adaptation of cognitive control to specific task demands, which leads to an error when these task demands change. Taken together, these results provide evidence that error-preceding brain activity can reflect adaptive adjustments rather than unsystematic fluctuations of cognitive control, and therefore, that these errors are actually a consequence of the adaptiveness of human cognition.

  5. 76 FR 13243 - Self-Regulatory Organizations; BATS Exchange, Inc.; Notice of Filing and Immediate Effectiveness...

    Science.gov (United States)

    2011-03-10

    ... Release No. 61869 (April 7, 2010), 75 FR 19449 (April 14, 2010) (SR-ISE-2010-25) (notice of filing and... month); Securities Exchange Act Release No. 61987 (April 27, 2010), 75 FR 24771 (May 5, 2010) (SR-C2...), 73 FR 7352 (February 7, 2008) (SR-Phlx-2008-08) (notice of filing and immediate effectiveness...

  6. Immediate Restoration of Immediate Implants in the Esthetic Zone of the Maxilla Via the Copy-Abutment Technique: 5-Year Follow-Up of Pink Esthetic Scores.

    Science.gov (United States)

    Fürhauser, Rudolf; Mailath-Pokorny, Georg; Haas, Robert; Busenlechner, Dieter; Watzek, Georg; Pommer, Bernhard

    2017-02-01

    Implant esthetics may benefit from individualized zirconia abutments copying the emergence profile of the natural tooth and delivered within days after immediate implant insertion. To investigate the esthetic outcome of the Copy-Abutment technique using the Pink Esthetic Score (PES). A total of 77 patients with single-tooth implants in the anterior maxilla restored at the day of immediate implant placement using Copy-Abutments and provisional crowns were followed-up after 1 week, 1 month, 4 months, 6 months, 1, 2, 3, 4, and 5 years to assess implant esthetics. PES ranged between 7 and 14 (median: 13) and improved significantly between the 6 month and 1 year follow-up (p process deficiency deteriorated (p = .016). Mean mucosal recession was 0.26 ± 0.86 mm (range: 0-1.6) after 5 years and not related to gingival biotype. Copy-Abutments for immediate restoration of implants in the esthetic zone show satisfactory long-term esthetic outcomes. © 2016 Wiley Periodicals, Inc.

  7. Electronic Services Monthly MI Report

    Data.gov (United States)

    Social Security Administration — This electronic services monthly MI report contains monthly MI data for most public facing online online applications such as iClaim, electronic access, Mobile wage...

  8. Immediate implant loading: A case report

    OpenAIRE

    Dhamankar, Dilip; Gupta, Arun R.; Mahadevan, Janani

    2010-01-01

    Dental implants have long provided an excellent treatment option to restore edentulous spaces. Successful formation of a direct bone to implant interface is the goal in implant therapy. Immediate loading is an alternative to two stage surgical procedure. Improved surgical instrumentation implants design, and surface topography changes the concept of two stages surgical to one stage surgical procedure.

  9. Rehearsal and recall in immediate memory

    NARCIS (Netherlands)

    Sanders, A.F.

    1961-01-01

    Experiments on the influence of rehearsal on the retention and recoil of digit combinations are described, from the results of which it appears that a rehearsal period facilitates recall by producing a transition from immediate to permanent memory. It further seems that some parts of the material pr

  10. The oncological implications of immediate breast reconstruction.

    NARCIS (Netherlands)

    Knottenbelt, A.; Spauwen, P.H.M.; Wobbes, Th.

    2004-01-01

    AIMS: The timing of breast reconstruction following mastectomy has been an area of contention. The purpose of this study was to report the oncologic safety of mastectomy and immediate breast reconstruction, primarily with a tissue expander. METHODS: We offered 54 patients (58 reconstructions) an

  11. Parallel Machine Scheduling Models with Fuzzy Parameters and Precedence Constraints: A Credibility Approach

    Institute of Scientific and Technical Information of China (English)

    HOU Fu-jun; WU Qi-zong

    2007-01-01

    A method for modeling the parallel machine scheduling problems with fuzzy parameters and precedence constraints based on credibility measure is provided.For the given n jobs to be processed on m machines, it is assumed that the processing times and the due dates are nonnegative fuzzy numbers and all the weights are positive, crisp numbers.Based on credibility measure, three parallel machine scheduling problems and a goal-programming model are formulated.Feasible schedules are evaluated not only by their objective values but also by the credibility degree of satisfaction with their precedence constraints.The genetic algorithm is utilized to find the best solutions in a short period of time.An illustrative numerical example is also given.Simulation results show that the proposed models are effective, which can deal with the parallel machine scheduling problems with fuzzy parameters and precedence constraints based on credibility measure.

  12. DUTY OF GROUNDS IN THE NEW CIVIL PROCEDURE CODE AND THE BINDING PRECEDENTS

    Directory of Open Access Journals (Sweden)

    Anderson Cortez Mendes

    2015-12-01

    Full Text Available The new Brazilian Civil Procedure Code instituted a model of binding precedents, to approach the legal system of common law countries. The legislator was already seeking the transformation of the STF and t he STJ of superior courts in supreme courts, with the transition from the exercises of the judgment control function in this case for assurance uniformity of interpretation of the law. So assumes special importance the duty of grounds, which is disciplined in article 489, allowing the management of binding system, with appropriate formation and application of the precedents. The article attempts therefore shed light on concepts inherent in the work with binding precedents, especially on those instilled in law by new Brazilian Civil Procedure Code, which are the ratio decidendi , the distinguishing and the overruling.

  13. A lattice traffic model with consideration of preceding mixture traffic information

    Institute of Scientific and Technical Information of China (English)

    Li Zhi-Peng; Liu Fu-Qiang; Sun Jian

    2011-01-01

    In this paper,the lattice model is presented,incorporating not only site information about preceding cars but also relative currents in front.We derive the stability condition of the extended model by considering a small perturbation around the homogeneous flow solution and find that the improvement in the stability of traffic flow is obtained by taking into account preceding mixture traffic information.Direct simulations also confirm that the traffic jam can be suppressed efficiently by considering the relative currents ahead,just like incorporating site information in front.Moreover,from the nonlinear analysis of the extended models,the preceding mixture traffic information dependence of the propagating kink solutions for traffic jams is obtained by deriving the modified KdV equation near the critical point using the reductive perturbation method.

  14. Immediate versus delayed postpartum insertion of contraceptive implant for contraception.

    Science.gov (United States)

    Sothornwit, Jen; Werawatakul, Yuthapong; Kaewrudee, Srinaree; Lumbiganon, Pisake; Laopaiboon, Malinee

    2017-04-22

    inclusion criteria of the review. We did not identify any ongoing trials. Two included studies were at low risk of selection, attrition, and reporting biases, but were at high risk of performance and detection biases due to the inability to blind participants to the intervention. One included study was at high risk of attrition bias. The overall quality of the evidence for each comparison ranged from very low to moderate; the main limitations were risk of bias and imprecision.Initiation rate of contraceptive implants at the first postpartum check-up visit was significantly higher in the immediate insertion group than in the delayed insertion group (RR 1.41, 95% CI 1.28 to 1.55; three studies, 410 participants; moderate quality evidence).There appeared to be little or no difference between the groups in the continuation rate of contraceptive implant used at six months after insertion (RR 1.02, 95% CI 0.93 to 1.11; two studies, 125 participants; low quality evidence) or at 12 months after insertion (RR 1.04; 95% CI 0.81 to 1.34; one study, 64 participants;very low quality evidence)Women who received an immediate postpartum contraceptive implant insertion had a higher mean number of days of abnormal vaginal bleeding within six weeks postpartum (MD 5.80 days, 95% CI 3.79 to 7.81; one study, 215 participants; low quality evidence) and a higher rate of other side effects in the first six weeks after birth (RR 2.06, 95% CI 1.38 to 3.06; one study, 215 participants; low quality evidence) than those who received a delayed postpartum insertion. There appeared to be little or no difference between the groups in heavy, irregular vaginal bleeding or associated severe cramping within 12 months (RR 1.01, 95% CI 0.72 to 1.44, one study, 64 participants;very low quality evidence).It was unclear whether there was any difference between the groups in scores for participant satisfaction on a 0-10 scale (MD -0.40, 95% CI -1.26 to 0.46, low quality evidence), or in rates of unintended pregnancy

  15. Use of oral antihypertensive medication preceding blood pressure elevation in hospitalized patients

    Directory of Open Access Journals (Sweden)

    Macedo Cristiano Ricardo Bastos de

    2001-01-01

    Full Text Available OBJECTIVE: To evaluate the frequency of oral antihypertensive medication preceding the increase in blood pressure in patients in a university hospital, the drug of choice, and the maintained use of antihypertensive medication. METHODS: Data from January to June 1997 from the University Hospital Professor Edgard Santos Pharmacy concerning the prescriptions of all inpatients were used. Variables included in the analysis were: antihypertensive medication prescription preceding increase in blood pressure, type of antihypertensive medication, gender, clinical or surgical wards, and the presence of maintained antihypertensive medication. RESULTS: The hospital admitted 2,532 patients, 1,468 in surgical wards and 818 in medical wards. Antihypertensive medication prescription preceding pressure increase was observed in 578 patients (22.8%. Nifedipine was used in 553 (95.7% and captopril in 25 (4.3%. In 50.7% of patients, prescription of antihypertensive medication was not associated with maintained antihypertensive medication. Prescription of antihypertensive drugs preceding elevation of blood pressure was significantly (p<0.001 more frequent on the surgical floor (27.5%; 405/1468 than on the medical floor (14.3%; 117/818. The frequency of prescription of antihypertensive drugs preceding elevation of blood pressure without maintained antihypertensive drugs and the ratio between the number of prescriptions of nifedipine and captopril were greater in surgical wards. CONCLUSION: The use of antihypertensive medication, preceding elevation of blood pressure (22.8% observed in admitted patients is not supported by scientific evidence. The high frequency of this practice may be even greater in nonuniversity hospitals.

  16. Developing Targeted Health Service Interventions Using the PRECEDE-PROCEED Model: Two Australian Case Studies

    Directory of Open Access Journals (Sweden)

    Jane L. Phillips

    2012-01-01

    Full Text Available Aims and Objectives. This paper provides an overview of the applicability of the PRECEDE-PROCEED Model to the development of targeted nursing led chronic illness interventions. Background. Changing health care practice is a complex and dynamic process that requires consideration of social, political, economic, and organisational factors. An understanding of the characteristics of the target population, health professionals, and organizations plus identification of the determinants for change are also required. Synthesizing this data to guide the development of an effective intervention is a challenging process. The PRECEDE-PROCEED Model has been used in global health care settings to guide the identification, planning, implementation, and evaluation of various health improvement initiatives. Design. Using a reflective case study approach, this paper examines the applicability of the PRECEDE-PROCEED Model to the development of targeted chronic care improvement interventions for two distinct Australian populations: a rapidly expanding and aging rural population with unmet palliative care needs and a disadvantaged urban community at higher risk of cardiovascular disease. Results. The PRECEDE-PROCEED Model approach demonstrated utility across diverse health settings in a systematic planning process. In environments characterized by increasing health care needs, limited resources, and growing community expectations, adopting planning tools such as PRECEDE-PROCEED Model at a local level can facilitate the development of the most effective interventions. Relevance to Clinical Practice. The PRECEDE-PROCEED Model is a strong theoretical model that guides the development of realistic nursing led interventions with the best chance of being successful in existing health care environments.

  17. Your Baby's Growth: 3 Months

    Science.gov (United States)

    ... to Be Smart About Social Media Your Baby's Growth: 3 Months KidsHealth > For Parents > Your Baby's Growth: 3 Months Print A A A What's in ... months of life are a period of rapid growth. Your baby will gain about 1 to 1½ ...

  18. Monthly energy review, August 1997

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1997-08-01

    The Monthly Energy Review for the month of August 1997, presents an overview of the Energy Information Administration`s recent monthly energy statistics. The statistics cover the major activities of U.S. production, consumption, trade, stocks, and prices for petroleum, natural gas, coal, electricity, and nuclear energy. Also included are international energy and thermal and metric conversion factors.

  19. A novel car following model considering average speed of preceding vehicles group

    Science.gov (United States)

    Sun, Dihua; Kang, Yirong; Yang, Shuhong

    2015-10-01

    In this paper, a new car following model is presented by considering the average speed effect of preceding vehicles group in cyber-physical systems (CPS) environment. The effect of this new consideration upon the stability of traffic flow is examined through linear stability analysis. A modified Korteweg-de Vries (mKdV) equation was derived via nonlinear analysis to describe the propagating behavior of traffic density wave near the critical point. Good agreement between the simulation and the analytical results shows that average speed of preceding vehicles group leads to the stabilization of traffic systems, and thus can efficiently suppress the emergence of traffic jamming.

  20. Precedent in the Sui Generis Legal Order: A Mine Run Approach

    DEFF Research Database (Denmark)

    Sadl, Urska; Hink, Sigrid

    2014-01-01

    In this article, we use case-to-case citation networks to explore the force of precedent in EU law. We introduce a novel methodology to analyse the extent to which references to past decisions act as reasons for decisions in subsequent cases and illustrate the approach on the European citizenship...... case-law citation network. We conclude that the cohesive pull of precedent in EU citizenship case-law is too weak to generate a coherent judicial doctrine, thereby confirming qualitative research on the subject. However, the incursions into competences of the Member States in areas, found only...

  1. Immediate allergic reaction to methylprednisolone with tolerance of other corticosteroids

    Directory of Open Access Journals (Sweden)

    Atanasković-Marković Marina

    2012-01-01

    Full Text Available Introduction. In spite of the wide usage of corticosteroids for the treatment of a plethora of diseases, sometimes they can induce immediate hypersensitivity reactions, which are however uncommon. Case Outline. We report a case of immediate allergic reaction induced by intravenous methylprednisolone given before operation for surgical repair of an arm contracture as a sequel of burns, which the child had tolerated a month before. Six weeks later the patient repeated the anaphylactic reaction during skin testing to methylprednisolone. In addition, basophile activation test with methylprednisolone (BAT was positive. Conclusion. This case report describes a patient who experienced intraoperative anaphylaxis and anaphylactic reaction induced by skin testing. This is the first report on induction of both anaphylactic reactions by methylprednisolone in the same child. Clinical findings, positive BAT and positive skin tests with methylprednisolone imply that the child developed type-I hypersensitivity. The lack of cross-reactivity with other corticosteroids emphasizes that the reactions were caused by the steroid molecule.

  2. Hemimaxillectomy for desmoplastic ameloblastoma with immediate temporalis flap reconstruction.

    Science.gov (United States)

    Elo, Jeffrey A; Tandon, Rahul; Allen, Chad N; Murray, Matthew D

    2014-08-01

    Ameloblastoma is one of the most common odontogenic tumors encountered, occurring more frequently than all other tumors combined, if one excludes the keratocystic odontogenic tumor. These tumors can cause severe expansion of the cortical bones and gross anatomic deformities. They can affect the dentition, causing tooth mobility and displacement. Fortunately, morbidity can be minimized with recognition on routine radiographic examination. The tissue may be unilocular or multilocular and has been described as having a "soap-bubble" appearance. Nevertheless, its radiographic appearance is insufficient to make a definitive diagnosis, because other tumors have similar appearance. Although the anatomic distribution and progression of ameloblastoma remain fairly consistent, alternative manifestations follow an atypical clinical course. One such variant is the desmoplastic ameloblastoma. We present a case of maxillary desmoplastic ameloblastoma treated with hemimaxillectomy and immediate reconstruction with temporalis flap that was recurrence-free at 36 months. Copyright © 2014 Elsevier Inc. All rights reserved.

  3. Chest physiotherapy in cystic fibrosis: short-term effects of autogenic drainage preceded by wet inhalation of saline versus autogenic drainage preceded by intrapulmonary percussive ventilation with saline.

    Science.gov (United States)

    Van Ginderdeuren, F; Verbanck, S; Van Cauwelaert, K; Vanlaethem, S; Schuermans, D; Vincken, W; Malfroot, A

    2008-01-01

    Chest physiotherapy has been used for many years to assist in the removal of abnormal viscid bronchial secretions in cystic fibrosis (CF) patients. This study compared the short-term effects of two physiotherapy regimens in patients with CF: autogenic drainage (AD) preceded by either saline inhalation ('saline(NEB) + AD') or by intrapulmonary percussive ventilation (IPV) with saline ('saline(IPV) + AD'). In a randomized crossover design, 20 clinically stable CF patients with similar pulmonary function at baseline received either 'saline(NEB) + AD' or 'saline(IPV) + AD' on 2 consecutive days. Transcutaneous oxygen saturation, heart rate, Borg dyspnea score and mucus wet weight were evaluated after 15 min of either saline(NEB) or saline(IPV), and after a subsequent 30 min of AD. There were no significant changes in oxygen saturation, heart rate or Borg score at any point of either physiotherapy intervention. There was no significant difference in sputum wet weight recovered with either saline(NEB) (2.2 +/- 1.8 g, mean +/- SD) or saline(IPV) (1.7 +/- 1.9 g) alone. Subsequent AD did produce significantly greater amounts of sputum wet weight (p < 0.0001 for both) than in the initial saline delivery period, yet the amount of wet weight was similar irrespective of whether AD was preceded by saline(NEB) (9.7 +/- 6.5 g) or saline(IPV) (11.6 +/- 7.3 g). Recovered sputum weight is similar whether AD is preceded by saline(NEB) or saline(IPV). The much greater amount of mucus obtained during the AD period than during the saline delivery period warrants further investigation. Copyright 2007 S. Karger AG, Basel.

  4. Immediate-type hypersensitivity to polyethylene glycols

    DEFF Research Database (Denmark)

    Wenande, E; Garvey, L H

    2016-01-01

    Polyethylene glycols (PEGs) or macrogols are polyether compounds widely used in medical and household products. Although generally considered biologically inert, cases of mild to life-threatening immediate-type PEG hypersensitivity are reported with increasing frequency. Nevertheless, awareness...... of PEG's allergenic potential remains low, due to a general lack of suspicion towards excipients and insufficient product labelling. Information on immediate-type reactions to PEG is limited to anecdotal reports, and the potential for PEG sensitization and cross-sensitization to PEGylated drugs...... to a range of unrelated products in hospital and at home. Increased awareness of PEG prevalence, PEG hypersensitivity, and improved access to PEG allergy testing, should facilitate earlier diagnosis and reduce the risk of inadvertent re-exposure. This first comprehensive review provides practical information...

  5. Selective immediate hypersensitivity reactions to NSAIDs.

    Science.gov (United States)

    Canto, Maria Gabriela; Andreu, Isabel; Fernandez, Javier; Blanca, Miguel

    2009-08-01

    Selective immediate reactions to NSAIDs imply that patients develop a urticarial/anaphylactic response to a single drug with good tolerance to other compounds. No systematic review of these reactions has yet been made. With the increase in consumption of NSAIDs, these have become one of the most common drugs inducing hypersensitivity reactions. Although cross-intolerance reactions are the most common, a significant proportion is selective responses. As specific IgE antibodies are not always found, there is only indirect evidence supporting an IgE-mediated mechanism in selective NSAID reactors. Selective immediate reactions to NSAIDs must be considered when a patient develops urticaria or anaphylaxis after intake of one drug with good tolerance to drugs from other groups or even a drug from the same group with a slightly different chemical structure. Further research is required to identify the antigenic determinant structures recognized.

  6. Reduced Activation of Left Orbitofrontal Cortex Precedes Blocked Vocalization: A Magnetoencephalographic Study

    Science.gov (United States)

    Sowman, Paul F.; Crain, Stephen; Harrison, Elisabeth; Johnson, Blake W.

    2012-01-01

    While stuttering is known to be characterized by anomalous brain activations during speech, very little data is available describing brain activations during stuttering. To our knowledge there are no reports describing brain activations that precede blocking. In this case report we present magnetoencephalographic data from a person who stutters…

  7. List scheduling in a parallel machine environment with precedence constraints and setup times

    NARCIS (Netherlands)

    Hurink, J.L.; Knust, S.

    2000-01-01

    We present complexity results which have influence on the strength of list scheduling in a parallel machine environment where additionally precedence constraints and sequence-dependent setup times are given and the makespan has to be minimized. We show that contrary to various other scheduling probl

  8. List scheduling in a parallel machine environment with precedence constraints and setup times

    NARCIS (Netherlands)

    Hurink, Johann; Knust, Sigrid

    2001-01-01

    We present complexity results which have influence on the strength of list scheduling in a parallel machine environment where additionally precedence constraints and sequence-dependent setup times are given and the makespan has to be minimized. We show that contrary to various other scheduling probl

  9. Ancient Uses of Meteoritic Metals as Precedent for Modern In-Situ Asteroid Mining

    Science.gov (United States)

    Mardon, Austin A.; Fawcett, Brett; Krispin, Daniel

    2016-05-01

    Given the strain on earth's supply of metal and the meteoritic content of meteorites, a prudent course would be to pursue in-situ asteroid mining of meteors for metal. There is a precedent for this going back to ancient Egypt; humans have always used the meteoritic content of meteorites to fashion everything from weapons to cosmetics.

  10. Local inhibition of GABA affects precedence effect in the inferior colliculus

    Institute of Scientific and Technical Information of China (English)

    Yanjun Wang; Ningyu Wang; Dan Wang; Jun Jia; Jinfeng Liu; Yan Xie; Xiaohui Wen; Xiaoting Li

    2014-01-01

    The precedence effect is a prerequisite for faithful sound localization in a complex auditory envi-ronment, and is a physiological phenomenon in which the auditory system selectively suppresses the directional information from echoes. Here we investigated how neurons in the inferior col-liculus respond to the paired sounds that produce precedence-effect illusions, and whether their ifring behavior can be modulated through inhibition with gamma-aminobutyric acid (GABA). We recorded extracellularly from 36 neurons in rat inferior colliculus under three conditions:no injection, injection with saline, and injection with gamma-aminobutyric acid. The paired sounds that produced precedence effects were two identical 4-ms noise bursts, which were deliv-ered contralaterally or ipsilaterally to the recording site. The normalized neural responses were measured as a function of different inter-stimulus delays and half-maximal interstimulus delays were acquired. Neuronal responses to the lagging sounds were weak when the inter-stimulus delay was short, but increased gradually as the delay was lengthened. Saline injection produced no changes in neural responses, but after local gamma-aminobutyric acid application, responses to the lagging stimulus were suppressed. Application of gamma-aminobutyric acid affected the normalized response to lagging sounds, independently of whether they or the paired sounds were contralateral or ipsilateral to the recording site. These observations suggest that local inhibition by gamma-aminobutyric acid in the rat inferior colliculus shapes the neural responses to lagging sounds, and modulates the precedence effect.

  11. 5 CFR 870.801 - Order of precedence and payment of benefits.

    Science.gov (United States)

    2010-01-01

    ... specific person or persons to receive life insurance benefits upon the death of an insured individual... the individual(s) entitled to receive Basic life insurance benefits under the statutory order of... SERVICE REGULATIONS (CONTINUED) FEDERAL EMPLOYEES' GROUP LIFE INSURANCE PROGRAM Order of Precedence...

  12. From Function to Context to Form: Precedents and Focus Shifts in the Form Creation Process

    DEFF Research Database (Denmark)

    Restrepo-Giraldo, John Dairo

    2005-01-01

    In design, the form creation process involves imagining, seeing and drawing. Translating the vague and imprecise initial ideas into sketches requires significant ability, and in this process, images of existing products (precedents) are a welcomed aid. Searching for them, however, is difficult, b...

  13. Strategy Precedes Operational Effectiveness: Aligning High Graduation Rankings with Competitive Graduation Grade Point Averages

    Science.gov (United States)

    Apprey, Maurice; Bassett, Kimberley C.; Preston-Grimes, Patrice; Lewis, Dion W.; Wood, Beverly

    2014-01-01

    Two pivotal and interconnected claims are addressed in this article. First, strategy precedes program effectiveness. Second, graduation rates and rankings are insufficient in any account of academic progress for African American students. In this article, graduation is regarded as the floor and not the ceiling, as it were. The ideal situation in…

  14. Renal vascular dysfunction precedes the development of renal damage in the hypertensive Fawn-Hooded rat

    NARCIS (Netherlands)

    Ochodnicky, Peter; Henning, Robert H.; Buikema, Hendrik J.; de Zeeuw, Dick; Provoost, Abraham P.; van Dokkum, Richard P. E.

    2010-01-01

    Ochodnicky P, Henning RH, Buikema HJ, de Zeeuw D, Provoost AP, van Dokkum RP. Renal vascular dysfunction precedes the development of renal damage in the hypertensive Fawn-Hooded rat. Am J Physiol Renal Physiol 298: F625-F633, 2010. First published December 9, 2009; doi:10.1152/ajprenal.00289.2009.-I

  15. Chromosomal effects on male and female components of sperm precedence in Drosophila.

    Science.gov (United States)

    Civetta, A; Clark, A G

    2000-04-01

    Recent experiments with Drosophila have demonstrated that the success of sperm in multiply mated females depends on the genotype of both the male and the female. To further characterize the distinction between male and female roles in sperm success, we scored variation in both sexes in sperm competitive ability among a set of chromosome replacement lines that allow identification of effects to each chromosome. We detected significant male and female effects on sperm precedence, defined as the ability of a male's ejaculate to displace resident sperm (P2) or avoid being displaced by subsequent matings (P1). Tests of effects of first, second and third chromosome substitutions revealed significant differences among third chromosomes in male sperm precedence (both P1 and P2) and a first x second chromosome interaction in female's effect on sperm precedence (only P1). We found no significant correlation between male and female effects on sperm precedence, suggesting that the variation found in both P1 and P2 has a different genetic cause in the two sexes.

  16. Self-Efficacy, Goal Orientations and Learning Strategies as Mediators between Preceding and Subsequent Academic Achievement

    Science.gov (United States)

    Diseth, Age

    2011-01-01

    High school grade point average (HSGPA), self-efficacy, goal orientations, learning strategies, and examination grade were measured in a sample of Norwegian undergraduate psychology students in order to investigate motives and strategies as mediators between preceding and subsequent academic achievement. Correlation analysis showed strong…

  17. Contributions from eye movement potentials to stimulus preceding negativity during anticipation of auditory stimulation

    DEFF Research Database (Denmark)

    Engdahl, Lis; Bjerre, Vicky K; Christoffersen, Gert R J

    2007-01-01

    Cognitive anticipation of a stimulus has been associated with an ERP called "stimulus preceding negativity" (SPN). A new auditory delay task without stimulus-related motor activity demonstrated a prefrontal SPN, present during attentive anticipation of sounds with closed eyes, but absent during...

  18. Dendritic calcium activity precedes inspiratory bursts in preBotzinger complex neurons

    DEFF Research Database (Denmark)

    Del Negro, Christopher A; Hayes, John A; Rekling, Jens C

    2011-01-01

    to evoke a Ca(2+)-activated inward current that contributes to inspiratory burst generation. We measured Ca(2+) transients by two-photon imaging dendrites while recording neuronal somata electrophysiologically. Dendritic Ca(2+) accumulation frequently precedes inspiratory bursts, particularly at recording...

  19. Promoting public transport as a subscription service: Effects of a free month travel card

    DEFF Research Database (Denmark)

    Thøgersen, John

    2009-01-01

    alone or together with a customised travel plan or a planning intervention. A control group receiving no intervention was also included. Attitudinal variables, car habits and travel behaviour were measured before and immediately after the intervention and again six months later. The only intervention...... offer had expired, but an effect was still evident five months later. Possible reasons and implications of this are discussed....

  20. Reinforcement Learning by Comparing Immediate Reward

    CERN Document Server

    Pandey, Punit; Kumar, Shishir

    2010-01-01

    This paper introduces an approach to Reinforcement Learning Algorithm by comparing their immediate rewards using a variation of Q-Learning algorithm. Unlike the conventional Q-Learning, the proposed algorithm compares current reward with immediate reward of past move and work accordingly. Relative reward based Q-learning is an approach towards interactive learning. Q-Learning is a model free reinforcement learning method that used to learn the agents. It is observed that under normal circumstances algorithm take more episodes to reach optimal Q-value due to its normal reward or sometime negative reward. In this new form of algorithm agents select only those actions which have a higher immediate reward signal in comparison to previous one. The contribution of this article is the presentation of new Q-Learning Algorithm in order to maximize the performance of algorithm and reduce the number of episode required to reach optimal Q-value. Effectiveness of proposed algorithm is simulated in a 20 x20 Grid world dete...

  1. Recessive dystrophic epidermolysis bullosa--oral rehabilitation using stereolithography and immediate endosseous implants.

    Science.gov (United States)

    Oliveira, Marcio A; Ortega, Karem L; Martins, Fabiana M; Maluf, Paulo S Z; Magalhães, Marina G

    2010-01-01

    Dental management of patients with epi-dermolysis bullosa (EB) is challenging because of the severe soft tissue lesions associated with this disease. A case history is presented where two immediate endosseous implants were placed in the mandible of a patient with recessive dystrophic EB using computer-aided technology to plan the surgery and prosthetic rehabilitation. After a 24-month follow-up, the prosthesis was stable with healthy asymptomatic soft tissue around the implants. The stereolithographic model provides a precise and noninvasive copy of the mandibular and maxillary arches of patients with EB for rehabilitation of the dentition with immediate endosseous implants and a prosthesis.

  2. Natural Gas Monthly, October 1993

    Energy Technology Data Exchange (ETDEWEB)

    1993-11-10

    The (NGM) Natural Gas Monthly highlights activities, events, and analyses of interest to public and private sector organizations associated with the natural gas industry. Volume and price data are presented each month for natural gas production, distribution, consumption, and interstate pipeline activities. Producer-related activities and underground storage data are also reported. From time to time, the NGM features articles designed to assist readers in using and interpreting natural gas information. This month`s feature articles are: US Production of Natural Gas from Tight Reservoirs: and Expanding Rule of Underground Storage.

  3. Natural gas monthly, May 1994

    Energy Technology Data Exchange (ETDEWEB)

    1994-05-25

    The Natural Gas Monthly (NGM) highlights activities, events, and analyses of interest to public and private sector organizations associated with the natural gas industry. Volume and price data are presented each month for natural gas production, distribution, consumption, and interstate pipeline activities. Producer-related activities and underground storage data are also reported. From time to time, the NGM features articles designed to assist readers in using and interpreting natural gas information. The featured articles for this month are: Opportunities with fuel cells, and revisions to monthly natural gas data.

  4. Monthly energy review, January 1998

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1998-01-01

    This report presents an overview of recent monthly energy statistics. Major activities covered include production, consumption, trade, stocks, and prices for fossil fuels, electricity, and nuclear energy.

  5. Natural gas monthly, July 1997

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1997-07-01

    The Natural Gas Monthly (NGM) highlights activities, events, and analyses of interest to public and private sector organizations associated with the natural gas industry. Volume and price data are presented each month for natural gas production, distribution, consumption, and interstate pipeline activities. Producer-related activities and underground storage data are also reported. From time to time, the NGM features articles designed to assist readers in using and interpreting natural gas information. The feature article this month is entitled ``Intricate puzzle of oil and gas reserves growth.`` A special report is included on revisions to monthly natural gas data. 6 figs., 24 tabs.

  6. Monthly Program Cost Report (MPCR)

    Data.gov (United States)

    Department of Veterans Affairs — The Monthly Program Cost Report (MPCR) replaces the Cost Distribution Report (CDR). The MPCR provides summary information about Veterans Affairs operational costs,...

  7. Sequential activation of microglia and astrocyte cytokine expression precedes increased Iba-1 or GFAP immunoreactivity following systemic immune challenge.

    Science.gov (United States)

    Norden, Diana M; Trojanowski, Paige J; Villanueva, Emmanuel; Navarro, Elisa; Godbout, Jonathan P

    2016-02-01

    Activation of the peripheral immune system elicits a coordinated response from the central nervous system. Key to this immune to brain communication is that glia, microglia, and astrocytes, interpret and propagate inflammatory signals in the brain that influence physiological and behavioral responses. One issue in glial biology is that morphological analysis alone is used to report on glial activation state. Therefore, our objective was to compare behavioral responses after in vivo immune (lipopolysaccharide, LPS) challenge to glial specific mRNA and morphological profiles. Here, LPS challenge induced an immediate but transient sickness response with decreased locomotion and social interaction. Corresponding with active sickness behavior (2-12 h), inflammatory cytokine mRNA expression was elevated in enriched microglia and astrocytes. Although proinflammatory cytokine expression in microglia peaked 2-4 h after LPS, astrocyte cytokine, and chemokine induction was delayed and peaked at 12 h. Morphological alterations in microglia (Iba-1(+)) and astrocytes (GFAP(+)), however, were undetected during this 2-12 h timeframe. Increased Iba-1 immunoreactivity and de-ramified microglia were evident 24 and 48 h after LPS but corresponded to the resolution phase of activation. Morphological alterations in astrocytes were undetected after LPS. Additionally, glial cytokine expression did not correlate with morphology after four repeated LPS injections. In fact, repeated LPS challenge was associated with immune and behavioral tolerance and a less inflammatory microglial profile compared with acute LPS challenge. Overall, induction of glial cytokine expression was sequential, aligned with active sickness behavior, and preceded increased Iba-1 or GFAP immunoreactivity after LPS challenge.

  8. Early cytoskeletal protein modifications precede overt structural degeneration in the DBA/2J mouse model of glaucoma

    Directory of Open Access Journals (Sweden)

    Gina Nicole Wilson

    2016-11-01

    Full Text Available Axonal transport deficits precede structural loss in glaucoma and other neurodegenerations. Impairments in structural support, including modified cytoskeletal proteins and microtubule-destabilizing elements, could be initiating factors in glaucoma pathogenesis. We investigated the time course of changes in protein levels and post-translational modifications in the DBA/2J mouse model of glaucoma. Using anterograde tract tracing of the retinal projection, we assessed major cytoskeletal and transported elements as a function of transport integrity in different stages of pathological progression. Using capillary-based electrophoresis, single- and multiplex immunosorbent assays, and immunofluorescence, we quantified hyperphosphorylated neurofilament-heavy chain, phosphorylated tau (ptau, calpain-mediated spectrin breakdown product (145/150kDa, β –tubulin, and amyloid-β42 proteins based on age and transport outcome to the superior colliculus (SC, the main retinal target in mice. Phosphorylated neurofilament-heavy chain (pNF-H was elevated within the optic nerve (ON and SC of 8-10 month-old DBA/2J mice, but was not evident in the retina until 12-15 months, suggesting that cytoskeletal modifications first appear in the distal retinal projection. As expected, higher pNF-H levels in the SC and retina were correlated with axonal transport deficits. Elevations in hyperphosphorylated tau (ptau occurred in ON and SC between 3-8 month of age while retinal ptau accumulations occurred at 12-15 months in DBA/2J mice. In vitro co-immunoprecipitation experiments suggested increased affinity of ptau for the retrograde motor complex protein, dynactin. We observed a transport-related decrease of β-tubulin in ON of 10-12 month-old DBA/2J mice, suggesting destabilized microtubule array. Elevations in calpain-mediated spectrin breakdown product were seen in ON and SC at the earliest age examined, well before axonal transport loss is evident. Finally, transport

  9. Opioid Treatment Patterns Following Prescription of Immediate-Release Hydrocodone.

    Science.gov (United States)

    Ben-Joseph, Rami; Bell, Jill A; Brixner, Diana; Kansal, Anuraag; Paramore, Clark; Chitnis, Abhishek; Holly, Pamela; S Burgoyne, Douglas

    2016-04-01

    Immediate-release (IR) hydrocodone is the most widely prescribed opioid in the United States; however, little is known about the utilization patterns and duration of opioid use among patients prescribed IR hydrocodone. A better understanding of the use of IR hydrocodone would result in more appropriate prescribing patterns of extended-release opioids. To assess downstream length of opioid therapy and utilization patterns of extended-release/long-acting (ER/LA) opioids among patients on IR hydrocodone to provide a better understanding of how IR and ER/LA opioids are used to manage pain. Retrospective analysis using health care claims from the Truven MarketScan Commercial, Medicare Supplemental, and Medicaid databases was performed. Patients prescribed IR hydrocodone during the 6-month baseline period (July 2011-December 2011) and with continuous enrollment for a 12-month follow-up period (2012) post-index date (January 1, 2012) were selected. Downstream length of therapy, defined as number of days supplied with opioids, and downstream use of ER/LA opioids during follow-up were examined by average pills per month (≤ 60 vs. > 60 pills per month) and days supply ( 60 pills per month than with ≤ 60 pills per month (7.8% vs. 1.2%, respectively, P 60 pills per month than with ≤ 60 pills per month. All results were consistent when examined by levels of days supply. A majority of the population prescribed IR hydrocodone was not prescribed opioid therapy beyond 2 months on average in the 1-year follow-up period. Only a small subset of patients with increased pills per month or days supply of IR hydrocodone in the baseline period continued to be high utilizers in the following year, averaging nearly 8 months of prescribed opioid use. A limited proportion of patients prescribed IR hydrocodone converted to ER/LA opioids. This knowledge can assist policymakers and physicians, providing an opportunity to identify small subsets of patients to improve ER/LA opioid prescribing

  10. Monthly energy review, November 1998

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1998-11-01

    The Monthly Energy Review (MER) presents an overview of the Energy Information Administration`s recent monthly energy statistics. The statistics cover the major activities of US production, consumption, trade, stocks, and prices for petroleum, natural gas, coal, electricity, and nuclear energy. Also included are international energy and thermal and metric conversion factors. 37 figs., 61 tabs.

  11. Natural gas monthly, February 1999

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1999-02-01

    The Natural Gas Monthly (NGM) highlights activities, events, and analyses of interest to public and private sector organizations associated with the natural gas industry. Volume and price data are presented each month for natural gas production, distribution, consumption, and interstate pipeline activities. Producer-related activities and underground storage data are also reported. 6 figs., 28 tabs.

  12. Monthly energy review: April 1996

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-04-01

    This monthly report presents an overview of energy statistics. The statistics cover the major activities of US production, consumption, trade, stocks, and prices for petroleum, natural gas, coal, electricity, and nuclear energy. A section is also included on international energy. The feature paper which is included each month is entitled ``Energy equipment choices: Fuel costs and other determinants.`` 37 figs., 59 tabs.

  13. ULTRAPLATE 30 month management report

    DEFF Research Database (Denmark)

    Jensen, Jens Dahl

    2003-01-01

    In the period from month 24 to month 30 focus has been on the work-package 3 activities concerning optimisation of the newly developed ULTRAPLATE technology towards specific industrial applications. Three main application areas have been pursued: 1) High- speed plating of lead free solder contact...

  14. Your Baby's Growth: 5 Months

    Science.gov (United States)

    ... to Be Smart About Social Media Your Baby's Growth: 5 Months KidsHealth > For Parents > Your Baby's Growth: 5 Months Print A A A What's in ... your child's birth, the doctor has been recording growth in weight, length, and head size (circumference) during ...

  15. Monthly energy review, November 1997

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1997-11-01

    The Monthly Energy Review (MER) presents an overview of the Energy Information Administration`s recent monthly energy statistics. The statistics cover the major activities of US production, consumption, trade, stocks, and prices for petroleum, natural gas, coal, electricity, and nuclear energy. Also included are international energy and thermal and metric conversion factors. 37 figs., 91 tabs.

  16. Natural gas monthly, November 1998

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1998-11-01

    The Natural Gas Monthly (NGM) highlights activities, events, and analyses of interest to public and private sector organizations associated with the natural gas industry. Volume and price data are presented each month for natural gas production, distribution, consumption, and interstate pipeline activities. Producer-related activities and underground storage data are also reported. 6 figs., 27 tabs.

  17. Natural gas monthly, January 1999

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1999-02-01

    The Natural Gas Monthly (NGM) highlights activities, events, and analyses of interest to public and private sector organizations associated with the natural gas industry. Volume and price data are presented each month for natural gas production, distribution, consumption, and interstate pipeline activities. Producer-related activities and underground storage data are also reported. 6 figs., 28 tabs.

  18. Monthly energy review, October 1998

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1998-10-01

    The Monthly Energy Review (MER) presents an overview of the Energy Information Administration`s recent monthly energy statistics. The statistics cover the major activities of US production, consumption, trade, stocks, and prices for petroleum, natural gas, coal, electricity, and nuclear energy. Also included are international energy and thermal and metric conversion factors. 37 figs., 61 tabs.

  19. Monthly energy review, June 1998

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1998-06-01

    The Monthly Energy Review (MER) presents an overview of the Energy Information Administration`s recent monthly energy statistics. The statistics cover the major activities of US production, consumption, trade, stocks, and prices for petroleum, natural gas, coal, electricity, and nuclear energy. Also included are international energy and thermal and metric conversion factors. 36 figs., 61 tabs.

  20. Monthly energy review, May 1999

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1999-05-01

    The Monthly Energy Review (MER) presents an overview of the Energy Information Administration`s recent monthly energy statistics. The statistics cover the major activities of US production, consumption, trade, stocks, and prices for petroleum, natural gas, coal, electricity, and nuclear energy. Also included are international energy and thermal and metric conversion factors. 37 figs., 61 tabs.

  1. Monthly energy review, January 1999

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1999-01-01

    The Monthly Energy Review (MER) presents an overview of the Energy Information Administration`s recent monthly energy statistics. The statistics cover the major activities of US production, consumption, trade, stocks, and prices for petroleum, natural gas, coal, electricity, and nuclear energy. Also included are international energy and thermal and metric conversion factors. 37 figs., 61 tabs.

  2. Monthly energy review, February 1999

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1999-02-01

    The Monthly Energy Review (MER) presents an overview of the Energy Information Administration`s recent monthly energy statistics. The statistics cover the major activities of US production, consumption, trade, stocks, and prices for petroleum, natural gas, coal, electricity, and nuclear energy. Also included are international energy and thermal and metric conversion factors. 37 figs., 73 tabs.

  3. Monthly energy review, March 1999

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1999-03-01

    The Monthly Energy Review (MER) presents an overview of the Energy Information Administration`s recent monthly energy statistics. The statistics cover the major activities of US production, consumption, trade, stocks, and prices for petroleum, natural gas, coal, electricity, and nuclear energy. Also included are international energy and thermal and metric conversion factors. 37 figs., 74 tabs.

  4. Natural gas monthly, December 1998

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1998-12-01

    The Natural Gas Monthly (NGM) highlights activities, events, and analyses of interest to public and private sector organizations associated with the natural gas industry. Volume and price data are presented each month for natural gas production, distribution, consumption, and interstate pipeline activities. Producer-related activities and underground storage data are also reported. 6 figs., 28 tabs.

  5. Left behind by Birth Month

    Science.gov (United States)

    Solli, Ingeborg Foldøy

    2017-01-01

    Utilizing comprehensive administrative data from Norway I investigate long-term birth month effects. I demonstrate that the oldest children in class have a substantially higher GPA than their younger peers. The birth month differences are larger for low-SES children. Furthermore, I find that the youngest children in class are lagging significantly…

  6. Monthly Energy Review, February 1996

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-02-26

    This monthly publication presents an overview of EIA`s recent monthly energy statistics, covering the major activities of U.S. production, consumption, trade, stocks, and prices for petroleum, natural gas, coal, electricity, and nuclear energy. Also included are international energy and thermal and metric conversion factors. Two brief descriptions (`energy plugs`) on two EIA publications are presented at the start.

  7. Haida Months of the Year.

    Science.gov (United States)

    Cogo, Robert

    Students are introduced to Haida vocabulary in this booklet which briefly describes the seasons and traditional seasonal activities of Southeastern Alaska Natives. The first section lists the months in English and Haida; e.g., January is "Taan Kungaay," or "Bear Hunting Month." The second section contains seasonal names in…

  8. Monthly energy review, November 1996

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-11-01

    The Monthly Energy Review (MER) presents an overview of the Energy Information Administration`s recent monthly energy statistics. The statistics cover the major activities of US production, consumption, trade, stocks, and prices for petroleum, natural gas, coal, electricity, and nuclear energy. Also included are international energy and thermal and metric conversion factors. 75 tabs.

  9. Monthly energy review, July 1998

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1998-07-01

    The Monthly Energy Review (MER) presents an overview of the Energy Information Administration`s recent monthly energy statistics. The statistics cover the major activities of US production, consumption, trade, stocks, and prices for petroleum, natural gas, coal, electricity, and nuclear energy. Also included are international energy and thermal and metric conversion factors. 37 figs. 73 tabs.

  10. Speech adaptation after treatment of full edentulism through immediate-loaded implant protocols.

    Science.gov (United States)

    Molly, Liene; Nackaerts, Olivia; Vandewiele, Katrien; Manders, Eric; van Steenberghe, Daniel; Jacobs, Reinhilde

    2008-01-01

    The objective of the present study was to evaluate the influence of immediate loading of implants on speech adaptation. Ten patients (mean age 54, 6 females) were examined before surgery and 1, 3, 6 and 12 months afterwards. Articulation analysis was done using objective DAT-recoded data evaluated by two groups of speech and language therapists and a computer software program. Besides, patient VAS-scores, myofunctional problems and hearing impairment were recorded and analysed. In the present study only one patient suffered from deteriorated speech after immediate loading. Other patients showed unaffected or improved articulation 3 to 6 months after surgery with a strident and interdental pronunciation mostly becoming addental. Furthermore, myofunctional problems occurred in one patient, other patients adapted to the new situation after three months. Hearing impairment did not influence speech pathology in this study. Immediate loading of oral implants does not seem to compromise the normal 3-6 months speech adaptation period. Whether such procedure presents advantages to the conventional 2-stage rehabilitation remains to be investigated.

  11. Global precedence, spatial frequency channels, and the statistics of natural images.

    Science.gov (United States)

    Hughes, H C; Nozawa, G; Kitterle, F

    1996-01-01

    A great deal of evidence suggests that early in processing, retinal images are filtered by parallel, spatial frequency selective channels. We attempt to incorporate this view of early vision with the principle of global precedence, which holds that Gestalt-like processes sensitive to global image configurations tend to dominate local feature processing in human pattern perception. Global precedence is inferred from the pattern of reaction times observed when visual patterns contain multiple cues at different levels of spatial scale. Specifically, it is frequently observed that global processing times are largely unaffected by conflicting local cues, but local processing times are substantially lengthened by conflicting global cues. The asymmetry of these effects suggests the dominant role of global configurations. Since global spatial information is effectively represented by low spatial frequencies, global precedence potentially implies a low frequency dominance. The thesis is that low spatial frequencies tend to be available before information carried by higher frequency bands, producing a coarse-to-fine temporal order in visual spatial perception. It is suggested that a variety of factors contribute to the "prior entry" of low frequency information, including the high contrast gain of the magnocellular pathway, the amplitude spectra typical of natural images, and inhibitory interactions between the parallel frequency-tuned channels. Evidence suggesting a close relationship between global precedence and spatial frequency channels is provided by observations that the essential features of the global precedence effect are obtained using patterns consisting of low and high frequency sinusoids. The hypothesis that these asymmetric interference effects are due to interactions between parallel spatial channels is supported by an analysis of reaction times (RTs), which shows that RTs to redundant low and high frequency cues produce less facilitation than predictions

  12. A reversible early oxidized redox state that precedes macromolecular ROS damage in aging non-transgenic and 3xTg-AD mouse neurons

    Science.gov (United States)

    Ghosh, D.; LeVault, K.; Barnett, A.; Brewer, G.J.

    2012-01-01

    The brain depends on redox electrons from NADH to produce ATP and oxyradicals (ROS). Since ROS damage and mitochondrial dysregulation are prominent in aging and Alzheimer’s disease (AD) and their relationship to redox state is unclear, we wanted to know whether an oxidative redox shift precedes these markers and leads to macromolecular damage in a mouse model of AD. We used the 3xTg-AD mouse model that displays cognitive deficits beginning at 4 months. Hippocampal/cortical neurons were isolated across the age-span and cultured in common nutrients to control for possible hormonal and vascular differences. We found an increase of NAD(P)H levels and redox state in non-transgenic neurons until middle age, followed by a decline in old age. The 3xTg-AD neurons maintained much lower resting NAD(P)H and redox state after 4 months, but the NADH regenerating capacity continuously declined with age beginning at 2 months. These redox characteristics were partially reversible with nicotinamide, a biosynthetic precursor of NAD+. Nicotinamide also protected against glutamate excitotoxicity. Compared to non-transgenic neurons, 3xTg-AD neurons possessed more mitochondria/neuron and lower glutathione levels which preceeded age-related increases in ROS levels. These glutathione deficits were again reversible with nicotinamide in 3xTg-AD neurons. Surprisingly, low macromolecular ROS damage was only elevated after 4 months in the 3xTg-AD neurons if anti-oxidants were removed. The present data suggest that a more oxidized redox state and a lower antioxidant glutathione defense can be dissociated from neuronal ROS damage, changes that precede the onset of cognitive deficits in the 3xTg-AD model. PMID:22539844

  13. Prognosis of Dental Implants Immediately Placed in Sockets Affected by Peri-implantitis: A Retrospective Pilot Study.

    Science.gov (United States)

    Anitua, Eduardo; Piñas, Laura; Begoña, Leire; Alkhraisat, Mohammad Hamdan

    The aim of this study was to describe a protocol and analyze the outcomes of immediate replacement of failed implants due to peri-implantitis. A total of 17 patients (mean age: 58 ± 10 years) had 22 failed implants that were immediately replaced. One implant failed 16 months after insertion, resulting in an implant survival rate of 94.7%. The mean follow-up time was 40 ± 16 months (range: 9-52 months) after insertion. Mesial and distal bone loss were 0.89 ± 0.62 mm and 0.97 ± 0.66 mm, respectively. Immediate implant replacement could be considered in the management of implant failure due to peri-implantitis.

  14. [Fetal pain: immediate and long term consequences].

    Science.gov (United States)

    Houfflin Debarge, Véronique; Dutriez, Isabelle; Pusniak, Benoit; Delarue, Eléonore; Storme, Laurent

    2010-06-01

    Several situations are potentially painful for fetuses, such as malformations and invasive procedures. Nociceptive pathways are known to be functional at 26 weeks. Even if it is not possible to evaluate the fetal experience of pain, it is essential to examine its immediate and long-term consequences. As early as the beginning of the second trimester, hemodynamic and hormonal responses are observed following fetal nociceptive stimulation, In experimental studies, long-term changes have been noted in the corticotrop axis, subsequent responses to pain, and behavior after perinatal nociceptive stimulation.

  15. [Immediate breast reconstruction for breast cancer].

    Science.gov (United States)

    Yamamoto, Daigo; Tanaka, Yoshihito; Tsubota, Yu; Sueoka, Noriko; Endo, Kayoko; Ogura, Tsunetaka; Nagumo, Yoshinori; Kwon, A-Hon

    2014-11-01

    We performed immediate breast reconstruction after nipple-sparing mastectomy or skin-sparing mastectomy and evaluated the reconstruction procedure, cosmesis, and complications. Among the 30 patients included in the study, 6 received latissimus dorsi flaps, 1 received a transverse rectus abdominis myocutaneous flap, 7 received deep inferior epigastric perforator flaps, 1 received an implant, and 15 received tissue expanders. In addition, the results were excellent in 25 patients, good in 3 patients, and poor in 2 patients. As the number of patients with breast cancer is increasing, the demand for breast reconstruction will increase. Therefore, it is essential to choose an appropriate method of breast reconstruction for each case.

  16. Atraumatic extraction and immediate implant installation: The importance of maintaining the contour gingival tissues

    Science.gov (United States)

    Tavarez, Rudys Rodolfo De Jesus; dos Reis, Washigton Luís Machado; Rocha, Adrycila Teixeira; Firoozmand, Leily Macedo; Bandéca, Matheus Coêlho; Tonetto, Mateus Rodrigues; Malheiros, Adriana Santos

    2013-01-01

    There is an accelerated resorption in the first six months after the extraction of the dental element, both horizontally and vertically. These clinical changes normally undertake the aesthetic result of prosthetic rehabilitation, and implant installation after the extraction can be a resource to decrease resorption. The clinical case described in this paper demonstrates a sequence of clinical atraumatic extraction, and then the Immediate installation provisionalization. It is concluded that when carefully indicated and planned, this technique can provide an immediate result promising with maintaining the tooth gingival contour. How to cite this article: Tavarez RR, Machado dos Reis WL, Rocha AT, Firoozmand LM, Bandéca MC, Tonetto MR, Malheiros AS. Atraumatic extraction and immediate implant installation: The importance of maintaining the contour gingival tissues. J Int Oral Health 2013; 5(6):113-8 . PMID:24453455

  17. [Clinical stability of immediate load of domestic micro-titanium screws for anchorage in orthodontics].

    Science.gov (United States)

    Zheng, Qing-zhong; Xie, Xing-qian; Xie, Xue-mei; Wang, Jian; Yu, Xiao-jia

    2009-10-01

    To investigate the immediate load stability of domestic micro-titanium screws for anchorage in orthodontics. Adult orthodontic patients needing the greatest anchorage were included in the study. Domestic micro-titanium screws were used to be orthodontic anchorage, immediate implantation and loading were conducted. A total of 52 implants of domestic micro-titanium anchorage in 20 patients were used. Forty-seven implants were successful in 20 patients,5 failed. The total loading time was 3-8 months. Domestic micro-titanium implant screws for anchorage can meet the needs of clinical orthodontics. However, immediate loading results in 10.4% failure rate, especially for the implant with a diameter of 1.2mmx7mm. Supported by Science and Technology Development Foundation of Fengxian District, Shanghai Municipality (Grant No. 090602).

  18. Dysregulation of lipid and amino acid metabolism precedes islet autoimmunity in children who later progress to type 1 diabetes

    Science.gov (United States)

    Orešič, Matej; Simell, Satu; Sysi-Aho, Marko; Näntö-Salonen, Kirsti; Seppänen-Laakso, Tuulikki; Parikka, Vilhelmiina; Katajamaa, Mikko; Hekkala, Anne; Mattila, Ismo; Keskinen, Päivi; Yetukuri, Laxman; Reinikainen, Arja; Lähde, Jyrki; Suortti, Tapani; Hakalax, Jari; Simell, Tuula; Hyöty, Heikki; Veijola, Riitta; Ilonen, Jorma; Lahesmaa, Riitta; Knip, Mikael; Simell, Olli

    2008-01-01

    The risk determinants of type 1 diabetes, initiators of autoimmune response, mechanisms regulating progress toward β cell failure, and factors determining time of presentation of clinical diabetes are poorly understood. We investigated changes in the serum metabolome prospectively in children who later progressed to type 1 diabetes. Serum metabolite profiles were compared between sample series drawn from 56 children who progressed to type 1 diabetes and 73 controls who remained nondiabetic and permanently autoantibody negative. Individuals who developed diabetes had reduced serum levels of succinic acid and phosphatidylcholine (PC) at birth, reduced levels of triglycerides and antioxidant ether phospholipids throughout the follow up, and increased levels of proinflammatory lysoPCs several months before seroconversion to autoantibody positivity. The lipid changes were not attributable to HLA-associated genetic risk. The appearance of insulin and glutamic acid decarboxylase autoantibodies was preceded by diminished ketoleucine and elevated glutamic acid. The metabolic profile was partially normalized after the seroconversion. Autoimmunity may thus be a relatively late response to the early metabolic disturbances. Recognition of these preautoimmune alterations may aid in studies of disease pathogenesis and may open a time window for novel type 1 diabetes prevention strategies. PMID:19075291

  19. Investigating the build-up of precedence effect using reflection masking

    DEFF Research Database (Denmark)

    Hartcher-O'Brien, Jessica; Buchholz, Jörg

    2006-01-01

    The auditory processing level involved in the build-up of precedence [Freyman et al., J. Acoust. Soc. Am. 90, 874–884 (1991)] has been investigated here by employing reflection masked threshold (RMT) techniques. Given that RMT techniques are generally assumed to address lower levels of the auditory...... signal processing, such an approach represents a bottom-up approach to the buildup of precedence. Three conditioner configurations measuring a possible buildup of reflection suppression were compared to the baseline RMT for four reflection delays ranging from 2.5–15 ms. No buildup of reflection...... suppression was observed for any of the conditioner configurations. Buildup of template (decrease in RMT for two of the conditioners), on the other hand, was found to be delay dependent. For five of six listeners, with reflection delay=2.5 and 15 ms, RMT decreased relative to the baseline. For 5- and 10-ms...

  20. Anomalous transport in fluid field with random waiting time depending on the preceding jump length

    Science.gov (United States)

    Zhang, Hong; Li, Guo-Hua

    2016-11-01

    Anomalous (or non-Fickian) transport behaviors of particles have been widely observed in complex porous media. To capture the energy-dependent characteristics of non-Fickian transport of a particle in flow fields, in the present paper a generalized continuous time random walk model whose waiting time probability distribution depends on the preceding jump length is introduced, and the corresponding master equation in Fourier-Laplace space for the distribution of particles is derived. As examples, two generalized advection-dispersion equations for Gaussian distribution and lévy flight with the probability density function of waiting time being quadratic dependent on the preceding jump length are obtained by applying the derived master equation. Project supported by the Foundation for Young Key Teachers of Chengdu University of Technology, China (Grant No. KYGG201414) and the Opening Foundation of Geomathematics Key Laboratory of Sichuan Province, China (Grant No. scsxdz2013009).

  1. Natural gas monthly, May 1997

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1997-05-01

    The Natural Gas Monthly highlights activities, events, and analyses of interest to public and private sector organizations associated with the natural gas industry. Volume and price data are presented each month for natural gas production, distribution, consumption, and interstate pipeline activities. Producer-related activities and underground storage data are also reported. From time to time, the NGM features articles designed to assist readers in using and interpreting natural gas information. The feature article this month is ``Restructuring energy industries: Lessons from natural gas.`` 6 figs., 26 tabs.

  2. Natural gas monthly, June 1994

    Energy Technology Data Exchange (ETDEWEB)

    1994-06-01

    The Natural Gas Monthly (NGM) highlights activities, events, and analyses of interest to public and private sector organizations associated with the natural gas industry. Volume and price data are presented each month for natural gas production, distribution, consumption, and interstate pipeline activities. Producer-related activities and underground storage data are also reported. From time to time, the NGM features articles designed to assist readers in using and interpreting natural gas information. The feature article this month is the executive summary from Natural Gas 1994: Issues and Trends. 6 figs., 31 tabs.

  3. Natural gas monthly, January 1994

    Energy Technology Data Exchange (ETDEWEB)

    1994-02-01

    The Natural Gas Monthly (NGM) highlights activities, events, and analyses of interest to public and private sector organizations associated with the natural gas industry. Volume and price data are presented each month for natural gas production, distribution, consumption, and interstate pipeline activities. Producer-related activities and underground storage data are also reported. From time to time, the NGM features articles designed to assist readers in using and interpreting natural gas information. The featured article for this month is on US coalbed methane production.

  4. Natural gas monthly, December 1997

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1997-12-01

    The Natural Gas Monthly highlights activities, events, and analyses of interest to public and private sector organizations associated with the natural gas industry. Volume and price data are presented each month for natural gas production, distribution, consumption, and interstate pipeline activities. Producer-related activities and underground storage data are also reported. From time to time, the NGM features articles designed to assist readers in using and interpreting natural gas information. The article this month is entitled ``Recent Trends in Natural Gas Spot Prices.`` 6 figs., 27 tabs.

  5. The importance of immediately loaded immediate post-extractive implants in esthetical rehabilitation: case series.

    Science.gov (United States)

    Danza, M; Fanali, S; Quaranta, A; Vozza, I

    2010-04-01

    The aim of this paper was to estimate, in a retrospective way, integration of hard and soft tissues in immediately loaded immediate postextractive implants. Benefits of this technique could be: single stage surgery, biological saving of tissues, aesthetic management of edentulism, good integration of both hard and soft tissues. Immediate loading of a postextractive implant seems also to produce a positive effect on the quality of perimplant soft tissues. The implants used in the present study have some advantages such as high auto-threading and auto-tapping ability, progressive increase of the thickness of the threads, at the apical and coronal level. All these features have helped to obtain a high primary stability.

  6. Diverticular colitis of the ascending colon preceding the onset of ulcerative colitis

    OpenAIRE

    Maeshiro, Tatsuji; Hokama, Akira; Kinjo, Tetsu; Fujita, Jiro

    2014-01-01

    We present a case of diverticular colitis of the ascending colon preceding the onset of ulcerative colitis. A 58-year-old man presented with positive faecal occult blood test. Colonoscopy disclosed diverticular colitis of the ascending colon. After a year's follow-up, typical ulcerative colitis developed and diverticular colitis improved. Diverticular colitis is a newly established disorder of chronic segmental mucosal inflammation affected by diverticular disease. There is increasing recogni...

  7. Application of the PRECEDE-PROCEED Planning Model in Designing an Oral Health Strategy.

    Science.gov (United States)

    Binkley, Catherine J; Johnson, Knowlton W

    2013-11-01

    Although the poor oral health of adults with intellectual and developmental disabilities (IDD) constitutes a significant health disparity in the United States, few interventions to date have produced lasting results. Moreover, there is minimal application of planning models to inform and design a theory-based strategy that has the potential to be effective and sustainable in this population. The PRECEDE-PROCEED planning model is being used to design and evaluate an oral health strategy for adults with IDD. The PRECEDE component involves assessing social, epidemiological, behavioral, environmental, educational, and ecological factors that informed the development of an intervention with underlying social cognitive theory assumptions. The PROCEED component consists of pilot-testing and evaluating the implementation of the strategy, its impact on mediators and outcomes of the population under study. A The PRECEDE assessment and strategy design results are presented including a conceptual framework and oral health strategy that are linked to social cognitive theory and Health Action Process Approach. We have developed a strategy consisting of a planned actions, capacity building, environmental adaptations, and caregiver reinforcement within group homes. The strategy is designed to increase caregiver self-efficacy, outcome expectancies, and behavioral capability, and also to create environmental influences that will lead to improved self-care behavior of the adult with IDD. It is anticipated that this strategy will improve the oral health and quality of life, including respiratory health, of individuals with IDD. The planned PROCEED component of the planning model includes a description of an in-process pilot study to refine the oral health strategy, along with a future randomized controlled clinical trial to demonstrate its effectiveness. The application of the PRECEDE-PROCEED planning model presented here demonstrates the feasibility of this planning model for

  8. A Decrease in Temperature and Humidity Precedes Human Rhinovirus Infections in a Cold Climate.

    Science.gov (United States)

    Ikäheimo, Tiina M; Jaakkola, Kari; Jokelainen, Jari; Saukkoriipi, Annika; Roivainen, Merja; Juvonen, Raija; Vainio, Olli; Jaakkola, Jouni J K

    2016-09-02

    Both temperature and humidity may independently or jointly contribute to the risk of human rhinovirus (HRV) infections, either through altered survival and spread of viruses in the environment or due to changes in host susceptibility. This study examined the relationship between short-term variations in temperature and humidity and the risk of HRV infections in a subarctic climate. We conducted a case-crossover study among conscripts (n = 892) seeking medical attention due to respiratory symptoms during their military training and identified 147 HRV cases by real-time PCR. An average temperature, a decline in daily ambient temperature and absolute humidity (AH) during the three preceding days of the onset (hazard period) and two reference periods (a week prior and after the onset) were obtained. The average daily temperature preceding HRV infections was -9.9 ± 4.9 °C and the average AH was 2.2 ± 0.9 g/m³. An average (odds ratios (OR) 1.07 (95% confidence interval (CI) 1.00-1.15)) and maximal (OR 1.08 (1.01-1.17)) change in temperature increased the risk of HRV infections by 8% per 1 °C decrease. An average (OR 1.20 (CI 1.03-1.40)) and maximal decrease (OR 1.13 (CI 0.96-1.34)) in AH increased the risk of HRV infection by 13% and 20% per 0.5 g/m³ decrease. A higher average temperature during the three preceding days was positively associated with HRV infections (OR 1.07 (CI 1.00-1.15)). A decrease rather than low temperature and humidity per se during the preceding few days increases the risk of HRV infections in a cold climate. The information is applicable to populations residing in cold climates for appropriate personal protection and prevention of adverse health effects.

  9. Factors preceding CRM readiness in small- and medium-sized tourism enterprises

    OpenAIRE

    Dinesh Vallabh; Laetitia Radder; Danie Venter

    2015-01-01

    Orientation: Customer relationship management (CRM) is important to organisations striving for competitive advantage through building relationships with their customers.Research purpose: This study identified the factors preceding CRM and assessed selected South African small- and medium-sized tourism enterprises’ (SMTEs) readiness for CRM.Motivation: CRM is likely to enhance SMTEs’ competitiveness. However, successful adoption and implementation of CRM is unlikely unless the organisation is ...

  10. DNA damage precedes apoptosis during the regression of the interdigital tissue in vertebrate embryos

    OpenAIRE

    2016-01-01

    DNA damage independent of caspase activation accompanies programmed cell death in different vertebrate embryonic organs. We analyzed the significance of DNA damage during the regression of the interdigital tissue, which sculpts the digits in the embryonic limb. Interdigit remodeling involves oxidative stress, massive apoptosis and cell senescence. Phosphorylation of H2AX mediated by ATM precedes caspase dependent apoptosis and cell senescence during interdigit regression. The association of γ...

  11. Organizational precedents for ownership and management of decentralized renewable-energy systems

    Energy Technology Data Exchange (ETDEWEB)

    Meunier, R.; Silversmith, J.A.

    1981-03-01

    Three existing organizational types that meet the decentralization criteria of local consumer ownership and control - cooperatives, Rural Electric Cooperatives, and municipal utilities - are examined. These three organizational precedents are analyzed in terms of their histories, structures, legal powers, sources of capital, and social and political aspects. Examples of related experiments with renewable energy technologies are given, and inferences are drawn regarding the organizations' suitability as vehicles for future implementation of decentralized renewable energy systems.

  12. Evidence for a neural source of the precedence effect in sound localization

    OpenAIRE

    Brown, Andrew D.; Jones, Heath G.; Kan, Alan; Thakkar, Tanvi; Stecker, G. Christopher; Goupell, Matthew J.; Litovsky, Ruth Y.

    2015-01-01

    Normal-hearing human listeners and a variety of studied animal species localize sound sources accurately in reverberant environments by responding to the directional cues carried by the first-arriving sound rather than spurious cues carried by later-arriving reflections, which are not perceived discretely. This phenomenon is known as the precedence effect (PE) in sound localization. Despite decades of study, the biological basis of the PE remains unclear. Though the PE was once widely attribu...

  13. Immediate vs delayed repair bond strength of a nanohybrid resin composite.

    Science.gov (United States)

    El-Askary, Farid S; El-Banna, Ahmed H; van Noort, Richard

    2012-06-01

    To evaluate both the immediate and water-stored repair tensile bond strength (TBS) of a nanohybrid resin composite using different bonding protocols. One hundred sixty half hourglass-shaped slabs were prepared. Eighty half-slabs were wet ground immediately after light curing using high-speed abrasive burs, while the other half-slabs were stored in water for one month (delayed) and then wet ground for repair. Each set of the 80 repaired slabs was split into two groups to be tested for TBS after 24 h or 1 month of water storage. For all repaired slabs, either immediate or delayed, four bonding procedures were used involving wet and dry bonding with a 3-step etch-and-rinse adhesive with or without silane pretreatment. TBS tests were performed at a crosshead speed of 0.5 mm/min. To determine the cohesive strength of the resin composite itself, which served as the reference, additional whole slabs were prepared and tested in tension after a 24-h (n = 10) and a 1-month storage period (n = 10). Failure modes were evaluated using a stereomicroscope at 40X magnification. Three-way ANOVA was run to test the effect of water storage, testing time, bonding protocols, and their interactions on the repair TBS, which was given as a percentage of the reference values. For the immediate repair groups, the repair TBS ranged from 40% to 61.9% after 24-h storage and from 26% to 53.1% after 1-month water storage compared to the TBS of the whole slabs. For the delayed repair group, the repaired TBS ranged from 47.2% to 63.6% for the 24-h repairs and from 32.2% to 44.2% for the test groups stored in water for 1 month. Three-way ANOVA revealed that water storage had no significant effect on the repair TBS (p = 0.619). Both testing time and bonding protocols had a significant effect on the repair TBS (p = 0.001). The interactions between the independent variables (water storage, testing time, and bonding protocols) had no significant effect (p = 0.067). The repair bond strength was

  14. Immediate implant loading with fixed dental restorations: An animal model study

    Directory of Open Access Journals (Sweden)

    Špadijer-Gostović Aleksandra

    2012-01-01

    Full Text Available Background/Aim. Immediate loading is considered to be the most innovative technique in contemporary implant dentistry. Recent clinical and experimental findings have demonstrated that only implants with high primary stability can be subjected to immediate loading protocol with predictable results. It is generally accepted that the most important prerequsite for successful osseointegration is achievement and maintenance of implant stability. The aim of this in vivo study was to investigate the possibility for successful application of immediate loading protocol in implant systems with different surface properties. Methods. In the experimental study 2 mongrel dogs were edentulated bilaterally in the mandibular and maxillary premolar areas. After 3 months implants were placed in a pattern 4 different commercially available implants per quadrant (n = 32: Mk III TiUnite (Nobel Biocare, Sweden, ITI TPS (Straumann, Switzerland, 3IOsseotite (Implant Innovation, USA and XiVE Cell-Plus (Friadent, Germany. Implants were subjected to immediate loading with 4 unit gold cast bridges, 2 days post implantation. The assessment of implant stability and immediate loading possibilities were done by performing Resonance frequency analysis (RFA. Results. After a 6- month loading period all bridges were in function and all implants occurred well osseointegrated. When summarizing the Implant Stability Quotient (ISQ values, it was noted that resonance frequency was significantly higher for mandibular implants. The results of this experimental setting showed that all evaluated surfaces achieved good implant stability. Increase of ISQ values was found for all implants in the mandible and partially decrease of ISQ values for maxillary implants after 6 months of functional loading with 4 unit bridges. Conclusions. Investigated endooseal implants did not show different degree of osseointegration, because there was not statisticaly significant difference among observed

  15. Histologic and histomorphometric behavior of microgrooved zirconia dental implants with immediate loading.

    Science.gov (United States)

    Delgado-Ruiz, Rafael Arcesio; Calvo-Guirado, Jose Luis; Abboud, Marcus; Ramirez-Fernandez, Maria Piedad; Maté-Sánchez de Val, José Eduardo; Mate-Sanchez, Jose Eduardo; Negri, Bruno; Rothamel, Daniel

    2014-12-01

    The study aims to assess the total soft tissue (ST) width, crestal bone level (CBL), bone-to-implant contact (BIC), and bone density (BD) for zirconia implants textured with microgrooved surfaces and immediately loaded. This study included 51 implants; one implant from each study group was retained for surface characterization. The 48 remaining implants were inserted randomly in premolar areas of both sides of the healed edentulous lower jaws of foxhound dogs. They were divided into three groups of 16: control (titanium); test A (zirconia), and test B (microgrooved zirconia). The implants were splinted and covered with an acrylic bridge. A split-mouth design was used and immediate occlusal loading was applied on one side, while the other side did not have occlusal contact. ST, CBL, BIC, and BD were evaluated after 3 months. The effects of immediate loading on these parameters were analyzed. All the implants were osseointegrated. ST was established at 3 months with mean values of 2.9 ± 0.4 mm for all groups. No differences were appreciated between loaded and unloaded sides regarding ST (p > .05). CBL showed a mean of 1.2 ± 0.3 mm for all groups without differences between loaded and unloaded sides (p > .05). BIC percentages were significantly higher for loaded all-microgrooved implants (p implants (p implants than unloaded. Within the limitations of the present study, it may be concluded that for zirconia dental implants with microgrooved surfaces and immediate loading, the thickness of STs remains stable resulting in 3 mm mean biologic width, that crestal bone preservation is related to insertion depth, and that higher BIC percentages and increased BD around implants microgrooved over the entire intraosseous area may be expected at 3 months following implant insertion and immediate loading. © 2013 Wiley Periodicals, Inc.

  16. Reprint of "Affective picture processing as a function of preceding picture valence: an ERP analysis".

    Science.gov (United States)

    Schupp, Harald T; Schmälzle, Ralf; Flaisch, Tobias; Weike, Almut I; Hamm, Alfons O

    2013-03-01

    Event-related brain potential (ERP) studies consistently revealed that a relatively early (early posterior negativity; EPN) and a late (late positive potential; LPP) ERP component differentiate between emotional and neutral picture stimuli. Two studies examined the processing of emotional stimuli when preceded either by pleasant, neutral, or unpleasant context images. In both studies, distinct streams of six pictures were shown. In Study 1, hedonic context was alternated randomly across the 180 picture streams. In Study 2, hedonic context sequences were blocked, resulting in 60 preceding sequences of pleasant, neutral, and unpleasant context valence, respectively. The main finding was that the valence of the preceding picture sequence had no significant effect on the emotional modulation of the EPN and LPP components. However, previous results were replicated in that emotional stimulus processing was associated with larger EPN and LPP components as compared to neutral pictures. These findings suggest that the prioritized processing of emotional stimuli is primarily driven by the valence of the current picture. Copyright © 2013 Elsevier B.V. All rights reserved.

  17. The value of auditing negative lower GI investigations preceding a final diagnosis of colorectal cancer.

    Science.gov (United States)

    Somasekar, A; James, L; Stephenson, B M; Thompson, I W; Vellacott, K D; Allison, M C

    2009-09-01

    To review all preceding 'negative' large bowel investigations in patients with a final diagnosis of colorectal cancer, and to examine whether delayed diagnosis was associated with worse outcome. Details were gathered on all patients with a new diagnosis of colorectal adenocarcinoma presenting over 4.5 years. For each patient the hospital's clinical workstation and radiology and endoscopy databases were interrogated for all flexible sigmoidoscopies, colonoscopies and barium enemas during the 5 years prior to diagnosis. Among the 570 patients, 28 (5%) had undergone colonoscopy and/or flexible sigmoidoscopy that had not shown colorectal cancer during the 5 years preceding final diagnosis, and a further 28 (5%) had undergone 'negative' barium enemas. Polyp surveillance might have missed four lesions destined to become malignant. Correspondingly there were three patients undergoing IBD surveillance found to have CRC, having had a negative complete colonoscopy within the preceding 5 years. Among patients undergoing de novo colonoscopy for diagnosis the true miss rate was only one patient per year. At August 2007, 29 (58%) of those with delayed diagnosis were still alive, compared with 216 (42%) of those diagnosed during initial investigation (chi2 = 5.04, P auditing the quality assurance of lower gastrointestinal diagnostic services. Despite the delay, late diagnosis was found to be associated with improved survival and a lower likelihood of metastatic disease.

  18. US Monthly Pilot Balloon Observations

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Monthly winds aloft summary forms summarizing Pilot Balloon observational data for the United States. Generally labeled as Form 1114, and then transitioning to Form...

  19. Monthly energy review, August 1993

    Energy Technology Data Exchange (ETDEWEB)

    1993-08-26

    This publication presents information for the month of August, 1993 on the following: Energy overview; energy consumption; petroleum; natural gas; oil and gas resource development; coal; electricity; nuclear energy; energy prices, and international energy.

  20. Monthly Energy Review, July 1992

    Energy Technology Data Exchange (ETDEWEB)

    None

    1992-07-27

    The Monthly Energy Review is prepared by the Energy Information Administration. Topics discussed include: Energy Overview, Energy Consumption, Petroleum, Natural Gas, Oil and Gas Resource Development, Coal, Electricity, Nuclear Energy, Energy Prices, International Energy. (VC)

  1. Monthly energy review, July 1997

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1997-07-01

    This document presents an overview of recent monthly energy statistics. Activities covered include: U.S. production, consumption, trade, stock, and prices for petroleum, coal, natural gas, electricity, and nuclear energy.

  2. Monthly energy review, August 1996

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-08-01

    This report presents an overview of recent monthly energy statistics. The statistics cover the major activities of U.S. production, consumption, trade, stocks, and prices for petroleum, coal, natural gas, electricity, and nuclear energy.

  3. Monthly energy review, August 1993

    Energy Technology Data Exchange (ETDEWEB)

    1993-08-26

    This publication presents information for the month of August, 1993 on the following: Energy overview; energy consumption; petroleum; natural gas; oil and gas resource development; coal; electricity; nuclear energy; energy prices, and international energy.

  4. Your Child's Development: 15 Months

    Science.gov (United States)

    ... Child Too Busy? Helping Your Child Adjust to Preschool School Lunches Kids and Food: 10 Tips for Parents Healthy Habits for TV, Video Games, and the Internet Your Child's Development: 15 Months KidsHealth > For Parents > Your Child's Development: ...

  5. Your Child's Development: 6 Months

    Science.gov (United States)

    ... Child Too Busy? Helping Your Child Adjust to Preschool School Lunches Kids and Food: 10 Tips for Parents Healthy Habits for TV, Video Games, and the Internet Your Child's Development: 6 Months KidsHealth > For Parents > Your Child's Development: ...

  6. Your Child's Development: 2 Months

    Science.gov (United States)

    ... Child Too Busy? Helping Your Child Adjust to Preschool School Lunches Kids and Food: 10 Tips for Parents Healthy Habits for TV, Video Games, and the Internet Your Child's Development: 2 Months KidsHealth > For Parents > Your Child's Development: ...

  7. Influence of immediate loading on provisional restoration in dental implant stability

    Science.gov (United States)

    Ikbal, M.; Odang, R. W.; Indrasari, M.; Dewi, R. S.

    2017-08-01

    The success of dental implant treatment is determined by the primary stability at placement. One factor that could influence this stability is occlusal loading through provisional restoration. Two types of loading protocols are usually used: immediate and delayed loading. However, some controversies remain about the influence of occlusal loading on implant stability. Therefore, the influence of immediate loading on implant stability must be studied. An animal study was conducted by placing nine dental implants in the mandibular jaw of three Macaca fascicularis. Provisional restorations with various occlusal contacts (no, light, and normal contact) were placed on the implant. The implant stability was measured using the Ostell ISQ three times: immediately (baseline) and at the first and second months after implant placement. The implant stability between implants with no and normal occlusal contact as well as light and normal occlusal contact showed significant differences (p 0.05) in implant stability was seen at the baseline and the first and second months after implant placement for all occlusal contact groups. Immediate loading influenced the implant stability, and provisional restoration of implant without occlusal contact showed the highest implant stability.

  8. Measuring Algorithm for the Distance to a Preceding Vehicle on Curve Road Using On-Board Monocular Camera

    Science.gov (United States)

    Yu, Guizhen; Zhou, Bin; Wang, Yunpeng; Wun, Xinkai; Wang, Pengcheng

    2015-12-01

    Due to more severe challenges of traffic safety problems, the Advanced Driver Assistance Systems (ADAS) has received widespread attention. Measuring the distance to a preceding vehicle is important for ADAS. However, the existing algorithm focuses more on straight road sections than on curve measurements. In this paper, we present a novel measuring algorithm for the distance to a preceding vehicle on a curve road using on-board monocular camera. Firstly, the characteristics of driving on the curve road is analyzed and the recognition of the preceding vehicle road area is proposed. Then, the vehicle detection and distance measuring algorithms are investigated. We have verified these algorithms on real road driving. The experimental results show that this method proposed in the paper can detect the preceding vehicle on curve roads and accurately calculate the longitudinal distance and horizontal distance to the preceding vehicle.

  9. Monthly energy review, August 1998

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1998-08-01

    The Monthly Energy Review (MER) presents an overview of the Energy Information Administration`s recent monthly energy statistics. The statistics cover the major activities of US production, consumption, trade, stocks, and prices for petroleum, natural gas, coal, electricity, and nuclear energy. Also included are international energy and thermal and metric conversion factors. The MER is intended for use by Members of Congress, Federal and State agencies, energy analysts, and the general public. 37 figs., 73 tabs.

  10. Natural gas monthly, July 1998

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1998-07-01

    The Natural Gas Monthly (NGM) highlights activities, events, and analyses of interest to public and private sector organizations associated with the natural gas industry. Volume and price data are presented each month for natural gas production, distribution, consumption, and interstate pipeline activities. Producer-related activities and underground storage data are also reported. From time to time, the NGM features articles designed to assist readers in using and interpreting natural gas information. 6 figs., 25 tabs.

  11. Natural gas monthly, June 1999

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1999-06-01

    The Natural Gas Monthly (NGM) highlights activities, events, and analyses of interest to public and private sector organizations associated with the natural gas industry. Volume and price data are presented each month for natural gas production, distribution, consumption, and interstate pipeline activities. Producer-related activities and underground storage data are also reported. From time to time, the NGM features articles designed to assist readers in using and interpreting natural gas information. 6 figs., 25 tabs.

  12. Natural gas monthly, August 1994

    Energy Technology Data Exchange (ETDEWEB)

    1994-08-24

    The Natural Gas Monthly (NGM) highlights activities, events, and analyses of interest to public and private sector organizations associated with the natural gas industry. Volume and price data are presented each month for natural gas production, distribution, consumption, and interstate pipeline activities. Producer-related activities and underground storage data are also reported. From time to time, the NGM features articles designed to assist readers in using and interpreting natural gas information.

  13. Natural gas monthly, June 1998

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1998-06-01

    The Natural Gas Monthly (NGM) highlights activities, events, and analyses of interest to public and private sector organizations associated with the natural gas industry. Volume and price data are presented each month for natural gas production, distribution, consumption, and interstate pipeline activities. Producer-related activities and underground storage data are also reported. From time to time, the NGM features articles designed to assist readers in using and interpreting natural gas information. 6 figs., 27 tabs.

  14. Natural gas monthly, April 1994

    Energy Technology Data Exchange (ETDEWEB)

    1994-04-26

    The National Gas Monthly (NGM) highlights activities, events, and analyses of interest to public and private sector organizations associated with the natural gas industry. Volume and price data are presented each month for natural gas production, distribution, consumption, and interstate pipeline activities. Producer-related activities and underground storage data are also reported. From time to time, the NGM features articles designed to assist readers in using and interpreting natural gas information.

  15. Natural gas monthly, September 1998

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1998-09-01

    The National Gas Monthly (NGM) highlights activities, events, and analyses of interest to public and private sector organizations associated with the natural gas industry. Volume and price data are presented each month for natural gas production, distribution, consumption, and interstate pipeline activities. Producer-related activities and underground storage data are also reported. From time to time, the NGM features articles designed to assist readers in using and interpreting natural gas information. 6 figs., 27 tabs.

  16. Natural gas monthly, June 1997

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1997-06-01

    The Natural Gas Monthly (NGM) highlights activities, events, and analyses of interest to public and private sector organizations associated with the natural gas industry. Volume and price data are presented each month for natural gas production, distribution, consumption, and interstate pipeline activities. Producer-related activities and underground storage data are also reported. From time to time, the NGM features articles designed to assist readers in using and interpreting natural gas information. 6 figs., 24 tabs.

  17. Natural gas monthly, October 1998

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1998-10-01

    The Natural Gas Monthly (NGM) highlights activities, events, and analyses of interest to public and private sector organizations associated with the natural gas industry. Volume and price data are presented each month for natural gas production, distribution, consumption, and interstate pipeline activities. Producer-related activities and underground storage data are also reported. From time to time, the NGM features articles designed to assist readers in using and interpreting natural gas information. 6 figs., 27 tabs.

  18. Monthly energy review, April 1998

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1998-04-01

    This report presents an overview of the Energy Information Administration`s recent monthly energy statistics. The statistics cover the major activities of U.S. production, consumption, trade, stocks, and prices for petroleum, natural gas, coal, electricity, and nuclear energy. Also included are international energy data. A brief summary of the monthly and historical comparison data is provided in Section 1 of the report. A highlight section of the report provides an assessment of summer 1997 motor gasoline price increases.

  19. Monthly energy review, April 1999

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1999-04-01

    The Monthly Energy Review (MER) presents an overview of the Energy Information Administration`s recent monthly energy statistics. The statistics cover the major activities of US production, consumption, trade, stocks, and prices for petroleum, natural gas, coal, electricity, and nuclear energy. Also included are international energy and thermal and metric conversion factors. The MER is intended for use by Members of Congress, Federal and State agencies, energy analysts, and the general public.

  20. Natural gas monthly, May 1999

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1999-05-01

    The Natural Gas Monthly (NGM) highlights activities, events, and analyses of interest to public and private sector organizations associated with the natural gas industry. Volume and price data are presented each month for natural gas production, distribution, consumption, and interstate pipeline activities. Producer-related activities and underground storage data are also reported. From time to time the NGM features articles designed to assist readers in using and interpreting natural gas information. 6 figs., 27 tabs.

  1. Natural gas monthly: December 1993

    Energy Technology Data Exchange (ETDEWEB)

    1993-12-01

    The Natural Gas Monthly (NGM) highlights activities, events, and analyses of interest to public and private sector organizations associated with the natural gas industry. Volume and price data are presented each month for natural gas production, distribution, consumption, and interstate pipeline activities. Producer-related activities and underground storage data are also reported. Articles are included which are designed to assist readers in using and interpreting natural gas information.

  2. Natural gas monthly, July 1998

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1998-07-01

    The Natural Gas Monthly (NGM) highlights activities, events, and analyses of interest to public and private sector organizations associated with the natural gas industry. Volume and price data are presented each month for natural gas production, distribution, consumption, and interstate pipeline activities. Producer-related activities and underground storage data are also reported. From time to time, the NGM features articles designed to assist readers in using and interpreting natural gas information. 6 figs., 25 tabs.

  3. Natural Gas Monthly, March 1996

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-03-25

    The Natural Gas Monthly (NGM) highlights activities, events, and analyses of interest to public and private sector organizations associated with the natural gas industry. Volume and price data are presented each month for natural gas production, distribution, consumption, and interstate pipeline activities. Producer-related activities and underground storage data are also reported. From time to time, the NGM features articles designed to assist readers in using and interpreting natural gas information.

  4. Natural gas monthly, July 1994

    Energy Technology Data Exchange (ETDEWEB)

    1994-07-20

    The Natural Gas Monthly (NGM) highlights activities, events, and analyses of interest to public and private sector organizations associated with the natural gas industry. Volume and price data are presented each month for natural gas production, distribution, consumption, and interstate pipeline activities. Producer-related activities and underground storage data are also reported. From time to time, the NGM features articles designed to assist readers in using and interpreting natural gas information.

  5. Natural gas monthly, November 1993

    Energy Technology Data Exchange (ETDEWEB)

    1993-11-29

    The Natural Gas Monthly (NGM) highlights activities, events, and analyses of interest to public and private sector organizations associated with the natural gas industry. Volume and price data are presented each month for natural gas production, distribution, consumption, and interstate pipeline activities. Producer-related activities and underground state data are also reported. From time to time, the NGM features articles designed to assist readers in using and interpreting natural gas information.

  6. Natural gas monthly, October 1995

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1995-10-23

    The Natural Gas Monthly highlights activities, events, and analyses of interest to public and private sector organizations associated with the natural gas industry. Volume and price data are presented each month for natural gas production, distribution, consumption, and interstate pipeline activities. Producer-related activities and underground storage data are also reported. A glossary of the terms used in this report is provided to assist readers in understanding the data presented in this publication. 6 figs., 30 tabs.

  7. HIV status, breastfeeding modality at 5 months and postpartum maternal weight changes over 24 months in rural South Africa.

    Science.gov (United States)

    Chetty, Terusha; Carter, Rosalind J; Bland, Ruth M; Newell, Marie-Louise

    2014-07-01

    To determine the effect of infant feeding practices on postpartum weight change among HIV-infected and -uninfected women in South Africa. In a non-randomised intervention cohort study of antiretroviral therapy-naïve women in South Africa, infants were classified as exclusive (EBF), mixed (MF) or non-breastfed (NBF) at each visit. We analysed infant feeding cumulatively from birth to 5 months using 24-hour feeding history (collected weekly for each of the preceding 7 days). Using generalised estimating equation mixed models, allowing for repeated measures, we compared postpartum weight change (kg) from the first maternal postpartum weight within the first 6 weeks (baseline weight) to each subsequent visit through 24 months among 2340 HIV-infected and -uninfected women with live births and at least two postpartum weight measurements. HIV-infected (-0.2 kg CI: -1.7 to 1.3 kg; P = 0.81) and -uninfected women (-0.5 kg; 95% CI: -2.1 to 1.2 kg; P = 0.58) had marginal non-significant weight loss from baseline to 24 months postpartum. Adjusting for HIV status, socio-demographic, pregnancy-related and infant factors, 5-month feeding modality was not significantly associated with postpartum weight change: weight change by 24 months postpartum, compared to the change in the reference EBF group, was 0.03 kg in NBF (95% CI: -2.5 to +2.5 kg; P = 0.90) and 0.1 kg in MF (95% CI: -3.0 to +3.2 kg; P = 0.78). HIV-infected and -uninfected women experienced similar weight loss over 24 months. Weight change postpartum was not associated with 5-month breastfeeding modality among HIV-infected and -uninfected women. © 2014 John Wiley & Sons Ltd.

  8. 29 CFR 780.307 - Exemption for employer's immediate family.

    Science.gov (United States)

    2010-07-01

    ... 29 Labor 3 2010-07-01 2010-07-01 false Exemption for employer's immediate family. 780.307 Section... 13(a)(6) Statutory Provisions § 780.307 Exemption for employer's immediate family. Section 13(a)(6)(B... other member of the employer's immediate family.” The requirements of this exemption, evident from the...

  9. 19 CFR 142.25 - Discontinuance of immediate delivery privileges.

    Science.gov (United States)

    2010-04-01

    ... SECURITY; DEPARTMENT OF THE TREASURY (CONTINUED) ENTRY PROCESS Special Permit for Immediate Delivery § 142.25 Discontinuance of immediate delivery privileges. (a) Authority of port director. The port director... 19 Customs Duties 2 2010-04-01 2010-04-01 false Discontinuance of immediate delivery privileges...

  10. 29 CFR 780.308 - Definition of immediate family.

    Science.gov (United States)

    2010-07-01

    ... 29 Labor 3 2010-07-01 2010-07-01 false Definition of immediate family. 780.308 Section 780.308... 13(a)(6) Statutory Provisions § 780.308 Definition of immediate family. The Act does not define the scope of “immediate family.” Whether an individual other than a parent, spouse or child will be...

  11. Is immediate adjunctive CBT more beneficial than delayed CBT in treating depression?: A Pilot Study.

    Science.gov (United States)

    Rizvi, Sakina J; Zaretsky, Ari; Schaffer, Ayal; Levitt, Anthony

    2015-03-01

    Cognitive-behavioral therapy (CBT) is an efficacious first-line therapy for patients with major depressive disorder (MDD). Due to the limited accessibility of CBT, long wait lists result in delayed treatment, which may affect treatment outcomes. The goal of this pilot study was to obtain preliminary data from a randomized controlled trial to determine whether delayed CBT reduces the effectiveness of the therapy compared to immediate CBT in patients with MDD receiving pharmacotherapy. Patients were randomized to receive immediate CBT (n=18) or to begin CBT after 6 months (n=20) and received 14 weekly sessions, followed by two additional booster sessions. During the active treatment months, patients in the immediate group demonstrated reductions in scores on the Beck Depression Inventory II (BDI-II) that were similar to those in the delayed CBT group. However, when the analysis was performed using only data from patients in the delayed group who were still in a depressive episode, there was an overall greater decrease in BDI-II scores in the immediate group vs. the delayed group over the active treatment months, but not specifically at the 6-month endpoint. These findings suggest delays in depression treatment, similar to what occurs with real-world wait list times, may not have a significant impact on the effectiveness of CBT in patients who are already receiving treatment as usual. However, such delays may affect the effectiveness of CBT in those patients who remain depressed during the time delay. A larger trial is necessary to confirm these findings. (Journal of Psychiatric Practice 2015;21:107-113).

  12. Effect of Educational Program, Based on PRECEDE and Trans-Theoretical Models, on Preventing Decline in Regular Physical Activity and Improving it among Students.

    Science.gov (United States)

    Rostami-Moez, Masomeh; Rezapur-Shahkolai, Forouzan; Hazavehei, Seyyed Mohammad-Mahdi; Karami, Manoochehr; Karimi-Shahanjarini, Akram; Nazem, Farzad

    2017-04-10

    Adolescents especially middle school girls do not follow 60 min of regular physical activity (RPA), recommended by WHO, and endure physical activity decline. Using theory-based interventional program, considering the age of decline in RPA, seems to be effective. The aim of this study was to determine the effects of educational program, based on PRECEDE and Trans-Theoretical models, on preventing decline in RPA and improving it among 7th grade girl students. Randomized controlled trial. This study was conducted on 7th grade girl students in Hamadan, west of Iran from 2015-16. Participants were divided into intervention (N=179) and control (N=165) groups by random assignment. Physical activity questionnaire for adolescents and the model-based questionnaire were used before and after intervention. Intervention included two months education and six months follow up. The effects of intervention were determined by statistical test and analysis of covariance using SPSS version 16. The higher change in the mean scores was observed in self-efficacy (0.86), counter condition (0.66) and helping relationship (0.57) in the intervention group (P≤0.001). In addition, a significant difference (P ≤0.001) was observed between the two groups 6 months after the intervention in all constructs of model. The mean score of doing physical activity in the intervention group increased from 2.50 to 3.17 that it was differed significantly from the control group (P≤0.001).  CONCLUSIONS: School based intervention using PRECEDE and Trans-Theoretical models might prevent girl students' RPA decline and improve their RPA.

  13. Immediate lexical integration of novel word forms

    Science.gov (United States)

    Kapnoula, Efthymia C.; McMurray, Bob

    2014-01-01

    It is well known that familiar words inhibit each other during spoken word recognition. However, we do not know how and under what circumstances newly learned words become integrated with the lexicon in order to engage in this competition. Previous work on word learning has highlighted the importance of offline consolidation (Gaskell & Dumay, 2003) and meaning (Leach & Samuel, 2007) to establish this integration. In two experiments we test the necessity of these factors by examining the inhibition between newly learned items and familiar words immediately after learning. Participants learned a set of nonwords without meanings in active (Exp 1) or passive (Exp 2) exposure paradigms. After training, participants performed a visual world paradigm task to assess inhibition from these newly learned items. An analysis of participants’ fixations suggested that the newly learned words were able to engage in competition with known words without any consolidation. PMID:25460382

  14. Output order in immediate serial recall.

    Science.gov (United States)

    Tan, Lydia; Ward, Geoff

    2007-07-01

    In two experiments, we examined the effect of output order in immediate serial recall (ISR). In Experiment 1, three groups of participants saw lists of eight words and wrote down the words in the rows corresponding to their serial positions in an eight-row response grid. One group was precued to respond in forward order, a second group was precued to respond in any order, and a third group was postcued for response order. There were significant effects of output order, but not of cue type. Relative to the forward output order, the free output order led to enhanced recency and diminished primacy, with superior performance for words output early in recall. These results were replicated in Experiment 2 using six-item lists, which further suggests that output order plays an important role in the primacy effect in ISR and that the recency items are most highly accessible at recall.

  15. Electric power monthly, May 1994

    Energy Technology Data Exchange (ETDEWEB)

    1994-05-01

    The Electric Power Monthly (EPM) presents monthly electricity statistics. The purpose of this publication is to provide energy decisionmakers with accurate and timely information that may be used in forming various perspectives on electric issues that lie ahead. Data in this report are presented for a wide audience including Congress, Federal and State agencies, the electric utility industry, and the general public. This publication provides monthly statistics for net generation, fossil fuel consumption and stocks, quantity and quality of fossil fuels, cost of fossil fuels, electricity sales, revenue, and average revenue per kilowatthour of electricity sold. Statistics by company and plant are published on the capability of new generating units, net generation, fuel consumption, fuel stocks, quantity and quality of fuel, and cost of fossil fuels.

  16. Electric power monthly, August 1993

    Energy Technology Data Exchange (ETDEWEB)

    1993-08-13

    The Electric Power Monthly (EPM) presents monthly electricity statistics. The purpose of this publication is to provide energy decisionmakers with accurate and timely information that may be used in forming various perspectives on electric issues that lie ahead. The EPM is prepared by the Survey Management Division; Office of Coal, Nuclear, Electric and Alternate Fuels, Energy Information Administration (EIA), Department of Energy. This publication provides monthly statistics at the US, Census division, and State levels for net generation, fossil fuel consumption and stocks, quantity and quality of fossil fuels, cost of fossil fuels, electricity sales, revenue, and average revenue per kilowatthour of electricity sold. Data on net generation, fuel consumption, fuel stocks, quantity and cost of fossil fuels are also displayed for the North American Electric Reliability Council (NERC) regions.

  17. Natural gas monthly, April 1998

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1998-04-01

    This issue of the Natural Gas Monthly presents the most recent estimates of natural gas data from the Energy Information Administration (EIA). Estimates extend through April 1998 for many data series. The report highlights activities, events, and analyses of interest to public and private sector organizations associated with the natural gas industry. Volume and price data are presented each month for natural gas production, distribution, consumption, and interstate pipeline activities. Producer-related activities and underground storage data are also reported. From time to time, feature articles are presented designed to assist readers in using and interpreting natural gas information. This issue contains the special report, ``Natural Gas 1997: A Preliminary Summary.`` This report provides information on natural gas supply and disposition for the year 1997, based on monthly data through December from EIA surveys. 6 figs., 28 tabs.

  18. Electric power monthly, April 1994

    Energy Technology Data Exchange (ETDEWEB)

    1994-04-01

    The Electric Power Monthly (EPM) presents monthly electricity statistics. The purpose of this publication is to provide energy decisionmakers with accurate and timely information that may be used in forming various perspectives on electric issues that lie ahead. This publication provides monthly statistics at the U.S., Census division, and State levels for net generation, fossil fuel consumption and stocks, quantity and quality of fossil fuels, cost of fossil fuels, electricity sales, revenue, and average revenue per kilowatthour of electricity sold. Data on net generation, fuel consumption, fuel stocks, quantity and cost of fossil fuels are also displayed for the North American Electric Reliability Council (NERC) regions. This April 1994 issue contains 1993 year-end data and data through January 1994.

  19. Electric power monthly, September 1993

    Energy Technology Data Exchange (ETDEWEB)

    1993-09-17

    The Electric Power Monthly (EPM) presents monthly electricity statistics. The purpose of this publication is to provide energy decisionmakers with accurate and timely information that may be used in forming various perspectives on electric issues that lie ahead. The EPM is prepared by the Survey Management Division; Office of Coal, Nuclear, Electric and Alternate Fuels, Energy Information Administration (EIA), Department of Energy. This publication provides monthly statistics at the US, Census division, and State levels for net generation, fossil fuel consumption and stocks, quantity and quality of fossil fuels, cost of fossil fuels, electricity sales, revenue, and average revenue per kilowatthour of electricity sold. Data on net generation, fuel consumption, fuel stocks, quantity and cost of fossil fuels are also displayed for the North American Electric Reliability Council (NERC) regions.

  20. Incipient Coombs' Test Negative Autoimmune Hemolytic Anemia Precedes Non-Hodgkin's Lymphoma%首发症状Coombs试验阴性自身免疫性溶血性贫血的非何杰金淋巴瘤

    Institute of Scientific and Technical Information of China (English)

    万岁桂; 林阳; 夏长青; 赵弘; 徐娟

    2012-01-01

    The cases of lymphoma accompanied or preceded by Coombs' test positive autoimmune hemolytic anemia (AIHA) have been reported.However,Coombs' test negative AIHA prior to the diagnosis of lymphoma was rarely described.Herein,this article reports a case of non-Hodgkin's lymphoma (NHL) preceded about 1.5 years by Coombs test negative AIHA.A woman aged 69 was diagnosed with HA based on the history and laboratory tests.Further studies revealed that this patient was negative with Coombs' test for IgG,IgM,IgA and C3.After all possible causes of HA,especially malignancies were ruled out,the patient was diagnosed with Coombs' test negative AIHA and treated with prednisolone.The patient responded well initially to steroid treatment.Two recurrences of acute HA were presented at time of 10 months post steroid cessation,and immediately after an attempt to withdraw steroid,respectively,but the hemolysis was effectively controlled by reinstitution of prednisolone.At third recurrence,however,the patient was no longer responding to steroid,and was found with cervical lymphadenopathy.Coombs' test for IgG,IgM,IgA and C3 remained negative.B cell NHL was diagnosed by pathology.After receiving 6 cycles of CHOP chemotherapy,the patient was lymphoma free,but the hemolysis was not improved,however,which was effectively controlled by the following low dose-rituximab(RTX) therapy.The patient was still kept in a remission of lymphoma free of anemia.In conclusion,this report presented a very rare case of NHL with Coombs' test negative AIHA as initial major clinical manifestation.%非何杰金淋巴瘤(NHL)伴发自身免疫性溶血性贫血(AIHA)或AIHA发生在NHL诊断之前或治疗过程中已有不少报道,但以Coombs试验阴性AIHA为首发症状的NHL鲜有报道.在此,本文报道1例1.5年反复溶血发作的Coombs试验阴性AIHA后合并NHL的患者.患者女性,69岁,根据病史和实验室检查诊断为Coombs试验阴性AIHA,给予强的松治疗后血红蛋白恢复正

  1. Electric power monthly, April 1993

    Energy Technology Data Exchange (ETDEWEB)

    1993-05-07

    The Electric Power Monthly is prepared by the Survey Management Division; Office of Coal, Nuclear, Electric and Alternate Fuels, Energy Information Administration (EIA), Department of Energy. This publication provides monthly statistics at the US, Census division, and State levels for net generation, fossil fuel consumption and stocks, quantity and quality of fossil fuels, cost of fossil fuels, electricity sales, revenue, and average revenue per kilowatthour of electricity sold. Data on net generation, fuel consumption, fuel stocks, quantity and cost of fossil fuels are also displayed for the North American Electric Reliability Council (NERC) regions.

  2. Natural gas monthly, August 1993

    Energy Technology Data Exchange (ETDEWEB)

    1993-08-25

    The Natural Gas Monthly (NGM) is prepared in the Data Operations Branch of the Reserves and Natural Gas Division, Office of Oil and Gas, Energy Information Administration (EIA), US Department of Energy (DOE). The NGM highhghts activities, events, and analyses of interest to public and private sector organizations associated with the natural gas industry. Volume and price data are presented each month for natural gas production, distribution, consumption, and interstate pipeline activities. Producer-related activities and underground storage data are also reported. From time to time, the NGM features articles designed to assist readers in using and interpreting natural gas information.

  3. Natural gas monthly, March 1997

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1997-03-01

    The Natural Gas Monthly (NGM) highlights activities, events, and analyses of interest to public and private sector organizations associated with the natural gas industry. Volume and price data are presented each month for natural gas production, distribution, consumption, and interstate pipeline activities. Producer-related activities and underground storage data are also reported. From time to time, the NGM features articles designed to assist readers in using and interpreting natural gas information. The feature article is entitled ``Natural gas analysis and geographic information systems.`` 6 figs., 27 tabs.

  4. Natural gas monthly, October 1996

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-10-01

    The Natural Gas Monthly (NGM) is prepared in the Data Operations Branch of the Reserves and Natural Gas Division, Office of Oil and Gas, Energy Information Administration (EIA), U.S. Department of Energy (DOE). The NGM highlights activities, events, and analyses of interest to public and private sector organizations associated with the natural gas industry. Volume and price data are presented each month for natural gas production, distribution, consumption, and interstate pipeline activities. Producer-related activities and underground storage data are also reported. From time to time, the NGM features articles designed to assist readers in using and interpreting natural gas information.

  5. Natural gas monthly, April 1999

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1999-05-06

    The Natural Gas Monthly (NGM) highlights activities, events, and analyses of interest to public and private sector organizations associated with the natural gas industry. Volume and price data are presented each month for natural gas production, distribution, consumption, and interstate pipeline activities. Producer-related activities and underground storage data are also reported. From time to time, the NGM features articles designed to assist readers in using and interpreting natural gas information. There are two feature articles in this issue: Natural gas 1998: Issues and trends, Executive summary; and Special report: Natural gas 1998: A preliminary summary. 6 figs., 28 tabs.

  6. Electric power monthly, June 1994

    Energy Technology Data Exchange (ETDEWEB)

    1994-06-01

    The Electric Power Monthly (EPM) presents monthly electricity statistics. The purpose of this publication is to provide energy decisionmakers with accurate and timely information that may be used in forming various perspectives on electric issues that lie ahead. Data in this report are presented for a wide audience including Congress, Federal and State agencies, the electric utility industry, and the general public. The EIA collected the information in this report to fulfill its data collection and dissemination responsibilities as specified in the Federal Energy Administration Act of 1974 (Public Law 93-275) as amended.

  7. Monthly energy review, June 1999

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1999-06-01

    The Monthly Energy Review (MER) presents an overview of the Energy Information Administration`s recent monthly energy statistics. The statistics cover the major activities of US production, consumption, trade, stocks, and prices for petroleum, natural gas, coal, electricity, and nuclear energy. Also included are international energy and thermal and metric conversion factors. The MER is intended for use by Members of Congress, Federal and State agencies, energy analysts, and the general public. EIA welcomes suggestions from readers regarding data series in the MER and in other EIA publications. 37 figs., 61 tabs.

  8. Natural gas monthly, April 1997

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1997-04-01

    The Natural Gas Monthly (NGM) highlights activities, events, and analyses of interest to public and private sector organizations associated with the natural gas industry. Volume and price data are present3ed each month for natural gas production, distribution, consumption, and interstate pipeline activities. Producer-related activities and underground storage data are also reported. From time to time, the NGM features articles designed to assist readers in using and interpreting natural gas information. The feature article is entitled ``Natural gas pipeline and system expansions.`` 6 figs., 27 tabs.

  9. ULTRAPLATE 30 month management report

    DEFF Research Database (Denmark)

    Jensen, Jens Dahl

    2003-01-01

    In the period from month 24 to month 30 focus has been on the work-package 3 activities concerning optimisation of the newly developed ULTRAPLATE technology towards specific industrial applications. Three main application areas have been pursued: 1) High- speed plating of lead free solder contacts......, 2) electroforming of tools for moulding of low-cost precision polymer devices and 3) deposition of magnetic alloys to be used in new planar micro-devices. Within each of the three studied application areas, the targeted output is a finished demonstrator to show the potential of the new ULTRAPLATE...

  10. Monthly energy review, July 1999

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1999-07-01

    The Monthly Energy Review (MER) presents an overview of the Energy Information Administration`s recent monthly energy statistics. The statistics cover the major activities of US production, consumption, trade, stocks, and prices for petroleum, natural gas, coal, electricity, and nuclear energy. Also included are international energy and thermal and metric conversion factors. The MER is intended for use by Members of Congress, Federal and State agencies, energy analysts, and the general public. EIA welcomes suggestions from readers regarding data series in the MER and in other EIA publications. 37 figs., 75 tabs.

  11. Electric power monthly, August 1994

    Energy Technology Data Exchange (ETDEWEB)

    1994-08-24

    The Electric Power Monthly (EPM) presents monthly electricity statistics. The purpose of this publication is to provide energy decisionmakers with accurate and timely information that may be used in forming various perspectives on electric issues that lie ahead. Data in this report are presented for a wide audience including Congress, Federal and State agencies, the electric utility industry, and the general public. The EIA collected the information in this report to fulfill its data collection and dissemination responsibilities as specified in the Federal Energy Administration Act of 1974 (Public Law 93-275) as amended.

  12. Electric power monthly, May 1993

    Energy Technology Data Exchange (ETDEWEB)

    1993-05-25

    The Electric Power Monthly (EPM) is prepared by the Survey Management Division; Office of Coal, Nuclear, Electric and Alternate Fuels, Energy Information Administration (EIA), Department of Energy. This publication provides monthly statistics at the US, Census division, and State levels for net generation, fossil fuel consumption and stocks, quantity and quality of fossil fuels, cost of fossil fuels, electricity sales, revenue, and average revenue per kilowatthour of electricity sold. Data on net generation, fuel consumption, fuel stocks, quantity and cost of fossil fuels are also displayed for the North American Electric Reliability Council (NERC) regions.

  13. Electric power monthly, July 1993

    Energy Technology Data Exchange (ETDEWEB)

    1993-07-29

    The Electric Power Monthly (EPM) presents monthly electricity statistics. The purpose of this publication is to provide energy decisionmakers with accurate and timely information that may be used in forming various perspectives on electric issues that lie ahead. Data in this report are presented for a wide audience including Congress, Federal and State agencies, the electric utility industry, and the general public. The EIA collected the information in this report to fulfill its data collection and dissemination responsibilities as specified in the Federal Energy Administration Act of 1974 (Public Law 93-275) as amended.

  14. Emotional distress regulation takes precedence over impulse control: if you feel bad, do it!

    Science.gov (United States)

    Tice, D M; Bratslavsky, E; Baumeister, R F

    2001-01-01

    Why do people's impulse controls break down during emotional distress? Some theories propose that distress impairs one's motivation or one's ability to exert self-control, and some postulate self-destructive intentions arising from the moods. Contrary to those theories, Three experiments found that believing that one's bad mood was frozen (unchangeable) eliminated the tendency to eat fattening snacks (Experiment 1), seek immediate gratification (Experiment 2), and engage in frivolous procrastination (Experiment 3). The implication is that when people are upset, they indulge immediate impulses to make themselves feel better, which amounts to giving short-term affect regulation priority over other self-regulatory goals.

  15. Behaviour of coconut mites preceding take-off to passive aerial dispersal.

    Science.gov (United States)

    Melo, J W S; Lima, D B; Sabelis, M W; Pallini, A; Gondim, M G C

    2014-12-01

    For more than three decades the coconut mite Aceria guerreronis Keifer is one of the most important pests of coconut palms and has recently spread to many coconut production areas worldwide. Colonization of coconut palms is thought to arise from mites dispersing aerially after take-off from other plants within the same plantation or other plantations. The underlying dispersal behaviour of the mite at take-off, in the airborne state and after landing is largely unknown and this is essential to understand how they spread from tree to tree. In this article we studied whether take-off to aerial dispersal of coconut mites is preceded by characteristic behaviour, whether there is a correlation between the body position preceding aerial dispersal and the direction of the wind, and whether the substrate (outer surface of coconut bracts or epidermis) and the wind speed matter to the decision to take-off. We found that take-off can sometimes be preceded by a raised body stance, but more frequently take-off occurs while the mite is walking or resting on its substrate. Coconut mites that become airborne assumed a body stance that had no relation to the wind direction. Take-off was suppressed on a substrate providing food to coconut mites, but occurred significantly more frequently on the outer surface of coconut bracts than on the surface of the fruit. For both substrates, take-off frequency increased with wind speed. We conclude that coconut mites have at least some degree of control over take-off for aerial dispersal and that there is as yet no reason to infer that a raised body stance is necessary to become airborne.

  16. Third chromosome candidate genes for conspecific sperm precedence between D. simulans and D. mauritiana.

    Science.gov (United States)

    Levesque, Lisa; Brouwers, Barb; Sundararajan, Vignesh; Civetta, Alberto

    2010-04-13

    Male - female incompatibilities can be critical in keeping species as separate and discrete units. Premating incompatibilities and postzygotic hybrid sterility/inviability have been widely studied as isolating barriers between species. In recent years, a number of studies have brought attention to postmating prezygotic barriers arising from male - male competition and male - female interactions. Yet little is known about the genetic basis of postmating prezygotic isolation barriers between species. Using D. simulans lines with mapped introgressions of D. mauritiana into their third chromosome, we find at least two D. mauritiana introgressions causing male breakdown in competitive paternity success. Eighty one genes within the mapped introgressed regions were identified as broad-sense candidates on the basis of male reproductive tract expression and male-related function. The list of candidates was narrowed down to five genes based on differences in male reproductive tract expression between D. simulans and D. mauritiana. Another ten genes were confirmed as candidates using evidence of adaptive gene coding sequence diversification in the D. simulans and/or D. mauritiana lineage. Our results show a complex genetic basis for conspecific sperm precedence, with evidence of gene interactions between at least two third chromosome loci. Pleiotropy is also evident from correlation between conspecific sperm precedence and female induced fecundity and the identification of candidate genes that might exert an effect through genetic conflict and immunity. We identified at least two loci responsible for conspecific sperm precedence. A third of candidate genes within these two loci are located in the 89B cytogenetic position, highlighting a possible major role for this chromosome position during the evolution of species specific adaptations to postmating prezygotic reproductive challenges.

  17. Third chromosome candidate genes for conspecific sperm precedence between D. simulans and D. mauritiana

    Directory of Open Access Journals (Sweden)

    Brouwers Barb

    2010-04-01

    Full Text Available Abstract Background Male - female incompatibilities can be critical in keeping species as separate and discrete units. Premating incompatibilities and postzygotic hybrid sterility/inviability have been widely studied as isolating barriers between species. In recent years, a number of studies have brought attention to postmating prezygotic barriers arising from male - male competition and male - female interactions. Yet little is known about the genetic basis of postmating prezygotic isolation barriers between species. Results Using D. simulans lines with mapped introgressions of D. mauritiana into their third chromosome, we find at least two D. mauritiana introgressions causing male breakdown in competitive paternity success. Eighty one genes within the mapped introgressed regions were identified as broad-sense candidates on the basis of male reproductive tract expression and male-related function. The list of candidates was narrowed down to five genes based on differences in male reproductive tract expression between D. simulans and D. mauritiana. Another ten genes were confirmed as candidates using evidence of adaptive gene coding sequence diversification in the D. simulans and/or D. mauritiana lineage. Our results show a complex genetic basis for conspecific sperm precedence, with evidence of gene interactions between at least two third chromosome loci. Pleiotropy is also evident from correlation between conspecific sperm precedence and female induced fecundity and the identification of candidate genes that might exert an effect through genetic conflict and immunity. Conclusions We identified at least two loci responsible for conspecific sperm precedence. A third of candidate genes within these two loci are located in the 89B cytogenetic position, highlighting a possible major role for this chromosome position during the evolution of species specific adaptations to postmating prezygotic reproductive challenges.

  18. Transient autonomic dysfunction precedes ST-segment depression in patients with syndrome X.

    Science.gov (United States)

    Ponikowski, P; Rosano, G M; Amadi, A A; Collins, P; Coats, A J; Poole-Wilson, P A; Kaski, J C

    1996-05-01

    Increased sympathetic drive has been suggested to play a role in the pathogenesis of syndrome X (angina pectoris, positive exercise testing, and angiographically normal coronary arteries). Heart rate variability (HRV) studies have shown that patients with syndrome X have an imbalance in autonomic nervous system activity (sympathetic predominance). However, it is not known if transient ST-segment depression which occurs in syndrome X during daily activities is related to this autonomic nervous system dysfunction. This study investigates the relation between the response of the autonomic nervous system, as assessed by HRV analysis, and the occurrence of transient ST-segment depression during 24-hour ambulatory electrocardiographic monitoring in 23 patients (4 men and 19 women, mean age 55 +/- 6 years) with syndrome X. The frequency-domain variables of HRV low-frequency (0.04 to 0.15 Hz) and high-frequency (0.15 to 0.40 Hz) power were measured at 6-minute intervals during the 30 minutes preceding the onset of transient ST-segment depression. Fourteen patients (61%) had > or = 1 episode of ST-segment depression in the 24 hours, whereas the remaining 9 patients (39%) had no significant ST-segment change. HRV measures differed according to whether or not ST-segment depression was associated with increased heart rate. Episodes of ST-segment depression associated with increased heart rate were preceded by a reduction of high-frequency power and an increase in the low-frequency--high-frequency ratio, whereas episodes of ST-segment depression not associated with increased heart rate showed no significant HRV changes. Low-frequency power remained unchanged irrespective of heart rate. Thus, in patients with syndrome X, a sympathovagal imbalance (sympathetic predominance due to vagal tone withdrawal) precedes episodes of ST-segment depression that are associated with an increased heart rate.

  19. Factors preceding CRM readiness in small- and medium-sized tourism enterprises

    Directory of Open Access Journals (Sweden)

    Dinesh Vallabh

    2015-02-01

    Full Text Available Orientation: Customer relationship management (CRM is important to organisations striving for competitive advantage through building relationships with their customers.Research purpose: This study identified the factors preceding CRM and assessed selected South African small- and medium-sized tourism enterprises’ (SMTEs readiness for CRM.Motivation: CRM is likely to enhance SMTEs’ competitiveness. However, successful adoption and implementation of CRM is unlikely unless the organisation is ready for it.Research design, approach and method: A quantitative research approach and survey questionnaire yielded primary data from 332 respondent organisations selected by systematic sampling. Exploratory factor analysis was used to identify the latent factors preceding CRM readiness. Organisational CRM readiness was assessed based on CRM maturity in terms of data collection, use and sharing throughout the organisation.Main findings: Respondent-organisations performed well on the four factors preceding CRM readiness − business strategy, customer strategy, touch points and competencies, skills and technology and also on data collections and use, but not on data sharing.Practical/Managerial implications: CRM practice is believed to assist organisations in tailoring products and services to customers’ needs, providing customer satisfaction, enhancing customer retention and ultimately improving the organisation’s competitiveness and profitability. CRM might fail if SMTEs do not have CRM-enabling conditions in place and a CRM readiness audit should therefore be performed.Contribution: The study contributes to a largely under-researched area concerning CRM in SMTEs by providing an improved understanding of the factors that will enable SMTEs to engage in CRM activities.

  20. Gestalt perception and the decline of global precedence in older subjects.

    Science.gov (United States)

    Staudinger, Markus R; Fink, Gereon R; Mackay, Clare E; Lux, Silke

    2011-01-01

    Our visual world is hierarchically organized. Hierarchical processing is frequently investigated using Navon figures (large letters made up of smaller ones). In young adults, many studies reported faster reaction times (RT) to target letters presented at the global level [i.e., global precedence (GP)]. Furthermore, an age-related decline of this GP has been reported. We tested whether deficits in perceptual grouping via Gestalt laws (Gestalt principles of Proximity and Continuity) might contribute to this decline. In a directed attention task with valid and invalid cues, 20 young (mean age 22) and 20 older (mean age 57) male subjects had to indicate whether a target letter appeared at the global or local level of a Navon figure. The number of local letters forming the global figure was modulated in 5 steps. As expected, during valid trials, young adults showed a GP that linearly increased with increasing numbers of local letters (i.e., GP enhancement). This suggests that GP is related to perceptual grouping via Gestalt laws. By contrast, the group of older subjects demonstrated no precedence effect in RT and a non-significant trend toward GP in error rates (ER). No GP enhancement with an increasing number of local elements was observed. Exploratory analysis revealed that individual insensitivity to the modulation of matrix density, as revealed by a lack of global RT acceleration, was restricted to subjects that showed an overall local precedence (LP). Because older subjects tended to more frequently display an insensitivity to matrix modulation and an LP, we conclude that deficient Gestalt detection as indicated by non-enhanced global RT might contribute to the RT-related decline of GP with age. Copyright © 2010 Elsevier Srl. All rights reserved.

  1. Natural gas monthly, August 1990

    Energy Technology Data Exchange (ETDEWEB)

    1990-11-05

    This report highlights activities, events, and analyses of interest to public and private sector oganizations associated with the natural gas industry. Volume and price data are presented each month for natural gas production, distribution, consumption, and interstate pipeline activities. Producer-related activities and underground storage data are also reported. 33 tabs.

  2. Monthly energy review, January 1996

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-01-01

    This document presents an overview of the Energy Information Administration`s recent monthly energy statistics. The statistics cover the major activities of U.S. production, consumption, trade, stocks, and prices for petroleum,natural gas, coal, electricity, and nuclear energy. Also included are international energy and thermal metric conversion factors.

  3. Monthly energy review, July 1996

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-07-01

    This document presents an overview of the recent monthly energy statistics from the Energy Information Administration (EIA). Statistical data covers activities of U.S. production, consumption, trade, stocks, and prices for fossil fuels , nuclear energy, and electricity. Also included are international energy and thermal and metric conversion factors.

  4. Monthly energy review, November 1993

    Energy Technology Data Exchange (ETDEWEB)

    1993-11-24

    The Monthly Energy Review gives information on production, distribution, and consumption for various energy sources, e.g. petroleum, natural gas, oil, coal, electricity, and nuclear energy. Some data is also included on international energy sources and supplies, the import of petroleum products into the US and pricing and reserves data (as applicable) for the various sources of energy listed above.

  5. Monthly energy review, November 1995

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1995-11-01

    This document presents an overview of the Energy Information Administration`s recent monthly energy statistics. The statistics cover the major activities of US production, consumption, trade, stocks, and prices for petroleum, natural gas, coal, electricity, and nuclear energy. International energy and thermal and metric conversion factors are included.

  6. Monthly energy review, April 1997

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1997-04-01

    This report presents an overview of monthly energy statistics. The statistics cover the major activities of U.S. production, consumption, trade, stocks, and prices for petroleum, natural gas, coal, electricity, and nuclear energy. International energy and thermal metric conversion factors are included.

  7. Monthly energy review, October 1993

    Energy Technology Data Exchange (ETDEWEB)

    1993-10-26

    The Monthly Energy Review gives information on production, distribution, and consumption for various energy sources, e.g. petroleum, natural gas, oil, coal, electricity, and nuclear energy. Some data is also included on international energy sources and supplies, the import of petroleum products into the US and pricing and reserves data (as applicable) for the various sources of energy listed above.

  8. Monthly energy review, June 1993

    Energy Technology Data Exchange (ETDEWEB)

    1993-06-25

    The Monthly Energy Review provides an overview of the production, distribution, and consumption of energy derived from petroleum, natural gas, coal, electricity, and nuclear energy. It also discusses oil and gas resource development, energy prices, and issues relevant to international energy markets.

  9. Periodic progress report, 12 months

    DEFF Research Database (Denmark)

    Juhl, Thomas Winther; Nielsen, Jakob Skov

    The work performed during the first 12 months of the project started with the establishment of the cutting theory for the cutting of heavy sections (phase 1). Phase 2 comprises the design of the first laboratory version cutting head with optics, nozzle systems and interfaces for the various...

  10. Monthly energy review, April 1994

    Energy Technology Data Exchange (ETDEWEB)

    1994-04-01

    The Monthly Energy Review contains statistical data on the following: energy consumption, petroleum, natural gas, oil and gas resource development, coal, electricity, nuclear energy, energy prices, and international energy. In addition, an energy overview is provided, and, for the April issue, Energy use and carbon emissions; Some international comparisons.

  11. Hepatitis Awareness Month PSA (:30)

    Centers for Disease Control (CDC) Podcasts

    2011-05-11

    May is National Hepatitis Awareness Month. This 30 second PSA discusses hepatitis and encourages listners to talk to their health care professional about getting tested.  Created: 5/11/2011 by National Center for HIV/AIDS, Viral Hepatitis, STD, and TB Prevention.   Date Released: 5/11/2011.

  12. Prediction of Malaysian monthly GDP

    Science.gov (United States)

    Hin, Pooi Ah; Ching, Soo Huei; Yeing, Pan Wei

    2015-12-01

    The paper attempts to use a method based on multivariate power-normal distribution to predict the Malaysian Gross Domestic Product next month. Letting r(t) be the vector consisting of the month-t values on m selected macroeconomic variables, and GDP, we model the month-(t+1) GDP to be dependent on the present and l-1 past values r(t), r(t-1),…,r(t-l+1) via a conditional distribution which is derived from a [(m+1)l+1]-dimensional power-normal distribution. The 100(α/2)% and 100(1-α/2)% points of the conditional distribution may be used to form an out-of sample prediction interval. This interval together with the mean of the conditional distribution may be used to predict the month-(t+1) GDP. The mean absolute percentage error (MAPE), estimated coverage probability and average length of the prediction interval are used as the criterions for selecting the suitable lag value l-1 and the subset from a pool of 17 macroeconomic variables. It is found that the relatively better models would be those of which 2 ≤ l ≤ 3, and involving one or two of the macroeconomic variables given by Market Indicative Yield, Oil Prices, Exchange Rate and Import Trade.

  13. Monthly energy review, March 1994

    Energy Technology Data Exchange (ETDEWEB)

    1994-03-29

    The Monthly Energy Review provides information on production, distribution, consumption, prices, imports, and exports for the following US energy sources: petroleum; petroleum products; natural gas; coal; electricity; and nuclear energy. The section on international energy contains data for world crude oil production and consumption, petroleum stocks in OECD countries, and nuclear electricity gross generation.

  14. Monthly energy review, December 1993

    Energy Technology Data Exchange (ETDEWEB)

    1993-12-22

    This document provides data on monthly energy use and fossil fuels. The following sections are included: Highlights: Emissions of greenhouse gases in the United States 1985--1990; Highlights: assessment of energy use in multibuilding facilities; energy overview; energy consumption; petroleum; natural gas; oil and gas resource development; coal; electricity; nuclear energy; energy prices; and international energy.

  15. Periodic progress report, 12 months

    DEFF Research Database (Denmark)

    Juhl, Thomas Winther; Nielsen, Jakob Skov

    The work performed during the first 12 months of the project started with the establishment of the cutting theory for the cutting of heavy sections (phase 1). Phase 2 comprises the design of the first laboratory version cutting head with optics, nozzle systems and interfaces for the various machi...

  16. Monthly energy review, October 1993

    Energy Technology Data Exchange (ETDEWEB)

    1993-10-26

    The Monthly Energy Review gives information on production, distribution, and consumption for various energy sources, e.g. petroleum, natural gas, oil, coal, electricity, and nuclear energy. Some data is also included on international energy sources and supplies, the import of petroleum products into the US and pricing and reserves data (as applicable) for the various sources of energy listed above.

  17. Monthly energy review, June 1990

    Energy Technology Data Exchange (ETDEWEB)

    1990-09-26

    The Monthly Energy Review presents current data on production, consumption, stocks, imports, exports, and prices of the principal energy commodities in the United States. Also included are data on international production of crude oil, consumption of petroleum products, petroleum stocks, and production of electricity from nuclear-powered facilities.

  18. Your Child's Development: 1 Month

    Science.gov (United States)

    ... Child Too Busy? Helping Your Child Adjust to Preschool School Lunches Kids and Food: 10 Tips for Parents Healthy Habits for TV, Video Games, and the Internet Your Child’s Development: 1 Month KidsHealth > For Parents > Your Child’s Development: ...

  19. Electric Power Monthly, July 1990

    Energy Technology Data Exchange (ETDEWEB)

    1990-10-12

    The Electric Power Monthly (EPM) is prepared by the Electric Power Division; Office of Coal, Nuclear, Electric and Alternate Fuels, Energy Information Administration (EIA), Department of Energy. This publication provides monthly statistics at the national, Census division, and State levels for net generation, fuel consumption, fuel stocks, quantity and quality of fuel, cost of fuel, electricity sales, and average revenue per kilowatthour of electricity sold. Data on net generation are also displayed at the North American Electric Reliability Council (NERC) region level. Additionally, company and plant level information are published in the EPM on capability of new plants, net generation, fuel consumption, fuel stocks, quantity and quality of fuel, and cost in fuel. Quantity, quality, and cost of fuel data lag the net generation, fuel consumption, fuel stocks, electricity sales, and average revenue per kilowatthour data by 1 month. This difference in reporting appears in the national, Census division, and State level tables. However, at the plant level, all statistics presented are for the earlier month for the purpose of comparison. 12 refs., 4 figs., 48 tabs.

  20. Electric power monthly, March 1995

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1995-03-20

    This report for March 1995, presents monthly electricity statistics for a wide audience including Congress, Federal and State agencies, the electric utility industry, and the general public. The purpose of this publication is to provide energy decisionmakers with accurate and timely information that may be used in forming various perspectives on electric issues that lie ahead.

  1. Natural gas monthly, July 1990

    Energy Technology Data Exchange (ETDEWEB)

    1990-10-03

    This report highlights activities, events, and analyses of interest to public and private sector organizations associated with the natural gas industry. Volume and price data are presented each month for natural gas production, distribution, consumption, and interstate pipeline activities. Producer-related activities and underground storage data are also reported. A glossary is included. 7 figs., 33 tabs.

  2. STD Awareness Month PSA (:30)

    Centers for Disease Control (CDC) Podcasts

    2011-04-19

    April is National STD Awareness Month. STDs can affect anyone. Many STDs don't have symptoms so it's important to get tested.  Created: 4/19/2011 by National Center for HIV/AIDS, Viral Hepatitis, STD, and TB Prevention.   Date Released: 4/19/2011.

  3. Solving a large-scale precedence constrained scheduling problem with elastic jobs using tabu search

    DEFF Research Database (Denmark)

    Pedersen, C.R.; Rasmussen, R.V.; Andersen, Kim Allan

    2007-01-01

    This paper presents a solution method for minimizing makespan of a practical large-scale scheduling problem with elastic jobs. The jobs are processed on three servers and restricted by precedence constraints, time windows and capacity limitations. We derive a new method for approximating the server...... exploitation of the elastic jobs and solve the problem using a tabu search procedure. Finding an initial feasible solution is in general -complete, but the tabu search procedure includes a specialized heuristic for solving this problem. The solution method has proven to be very efficient and leads...

  4. Onset of Bonding Plasmon Hybridization Preceded by Gap Modes in Dielectric Splitting of Metal Disks

    DEFF Research Database (Denmark)

    Frederiksen, Maj; Bochenkov, Vladimir; Ogaki, Ryosuke;

    2013-01-01

    Dielectric splitting of nanoscale disks was studied experimentally and via finite-difference time-domain (FDTD) simulations through systematic introduction of multiple ultrathin dielectric layers. Tunable, hybridized dark bonding modes were seen with first-order gap modes preceding the appearance...... of bonding dipole−dipole disk modes. The observed bright dipolar mode did not show the energy shift expected from plasmon hybridization but activated dark higher order gap modes. Introducing lateral asymmetry was shown to remodel the field distribution resulting in 3D asymmetry that reoriented the dipole...

  5. A Decrease in Temperature and Humidity Precedes Human Rhinovirus Infections in a Cold Climate

    Directory of Open Access Journals (Sweden)

    Tiina M. Ikäheimo

    2016-09-01

    Full Text Available Both temperature and humidity may independently or jointly contribute to the risk of human rhinovirus (HRV infections, either through altered survival and spread of viruses in the environment or due to changes in host susceptibility. This study examined the relationship between short-term variations in temperature and humidity and the risk of HRV infections in a subarctic climate. We conducted a case-crossover study among conscripts (n = 892 seeking medical attention due to respiratory symptoms during their military training and identified 147 HRV cases by real-time PCR. An average temperature, a decline in daily ambient temperature and absolute humidity (AH during the three preceding days of the onset (hazard period and two reference periods (a week prior and after the onset were obtained. The average daily temperature preceding HRV infections was −9.9 ± 4.9 °C and the average AH was 2.2 ± 0.9 g/m3. An average (odds ratios (OR 1.07 (95% confidence interval (CI 1.00–1.15 and maximal (OR 1.08 (1.01–1.17 change in temperature increased the risk of HRV infections by 8% per 1 °C decrease. An average (OR 1.20 (CI 1.03–1.40 and maximal decrease (OR 1.13 (CI 0.96–1.34 in AH increased the risk of HRV infection by 13% and 20% per 0.5 g/m3 decrease. A higher average temperature during the three preceding days was positively associated with HRV infections (OR 1.07 (CI 1.00–1.15. A decrease rather than low temperature and humidity per se during the preceding few days increases the risk of HRV infections in a cold climate. The information is applicable to populations residing in cold climates for appropriate personal protection and prevention of adverse health effects.

  6. Optimal Parallel Algorithms for Two Processor Scheduling with Tree Precedence Constraints

    OpenAIRE

    Ernst W. Mayr; Hans Stadtherr

    2016-01-01

    Consider the problem of finding a minimum length schedule for an unit execution time tasks on m processors with tree-like precedence constraints. A sequential algorithm can solve this problem in linear time. The fastest known parallel algorithm needs O(log n) time using n^2 processors. For the case m=2 we present two work optimal parallel algorithms that produce greedy optimal schedules for intrees and outtrees. Both run in O(log n) time using n/(log n) processors of an EREW PRAM.

  7. Takotsubo cardiomyopathy and thrombotic thrombocytopenic purpura preceding a lupus diagnosis: a case report.

    Science.gov (United States)

    Georgiades, F; Demosthenous, S; Braimi, M; Tsitskari, T; Psarelis, S

    2015-11-01

    Takotsubo cardiomyopathy, a rare stress-related cardiomyopathy, has been observed in a few cases secondary to systemic lupus erythematosus (SLE). Herein, we report an unusual case where a postmenopausal woman presented initially with Takotsubo syndrome, later developed thrombotic thrombocytopenic purpura and cerebrovascular events, initially without clinical or laboratory features of SLE. During the course of her illness, she was found to satisfy four of the Systemic Lupus International Collaborating Clinics classification criteria for a SLE diagnosis. This unique presentation of our patient, initially with Takotsubo cardiomyopathy, the development of thrombotic thrombocytopenic purpura and cerebrovascular events preceding the diagnosis of SLE illustrates the importance of clinical observation and follow-up.

  8. T-body formation precedes virus-like particle maturation in S. cerevisiae.

    Science.gov (United States)

    Malagon, Francisco; Jensen, Torben Heick

    2011-01-01

    T-bodies are localized S. cerevisiae RNPs containing Ty1 retroviral components and speculated to play a role in the assembly of virus-like particles (VLPs). Mapping requirements for T-body formation, we demonstrate that ectopic expression of immature TyA1/Gag (Gag-p49), a structural component of the Ty1 capsid, is sufficient for T-body formation both under normal conditions as well as in a strain background devoid of endogenous Gag. Moreover, T-bodies are readily formed when Ty1 transposition is blocked. Thus, T-bodies represent an early stage in the Ty1 life cycle, preceding VLP maturation.

  9. Your Child's Development: 1 Year (12 Months)

    Science.gov (United States)

    ... Kids For Parents MORE ON THIS TOPIC Your Child's Checkup: 1 Year (12 Months) Your Baby's Growth: 12 Months Your Baby's Hearing, Vision, and Other Senses: 12 Months Sleep and Your 8- to 12-Month-Old Growth ...

  10. Petroleum supply monthly, March 1994

    Energy Technology Data Exchange (ETDEWEB)

    1994-03-30

    Data presented in the Petroleum Supply Monthly (PSM) describe the supply and disposition of petroleum products in the United States and major US geographic regions. The data series describe production, imports and exports, inter-Petroleum Administration for Defense (PAD) District movements, and inventories by the primary suppliers of petroleum products in the United States (50 States and the District of Columbia). The reporting universe includes those petroleum sectors in primary supply. Included are: petroleum refiners, motor gasoline blenders, operators of natural gas processing plants and fractionators, inter-PAD transporters, importers, and major inventory holders of petroleum products and crude oil. When aggregated, the data reported by these sectors approximately represent the consumption of petroleum products in the United States. Data presented in the PSM are divided into two sections: Summary Statistics and Detailed Statistics. The tables and figures in the Summary Statistics section of the PSM present a time series of selected petroleum data on a US level. Most time series include preliminary estimates for one month based on the Weekly Petroleum Supply Reporting System; statistics based on the most recent data from the Monthly Petroleum Supply Reporting System (MPSRS); and statistics published in prior issues of the PSM and PSA. The Detailed Statistics tables of the PSM present statistics for the most current month available as well as year-to-date. In most cases, the statistics are presented for several geographic areas -- the United States (50 States and the District of Columbia), five PAD Districts, and 12 Refining Districts. At the US and PAD District level, the total volume and the daily rate of activities are presented. The statistics are developed from monthly survey forms submitted by respondents to the EIA and from data provided from other sources.

  11. Petroleum supply monthly, June 1993

    Energy Technology Data Exchange (ETDEWEB)

    1993-06-28

    Data presented in the Petroleum Supply Monthly (PSM) describe the supply and disposition of petroleum products in the United States and major US geographic regions. The data series describe production, imports and exports, inter-Petroleum Administration for Defense (PAD) District movements, and inventories by the primary suppliers of petroleum products in the United States (50 States and the District of Columbia). The reporting universe includes those petroleum sectors in primary supply. Included are: petroleum refiners, motor gasoline blenders, operators of natural gas processing plants and fractionators, inter-PAD transporters, importers, and major inventory holders of petroleum products and crude oil. When aggregated, the data reported by these sectors approximately represent the consumption of petroleum products in the United States. Data presented in the PSM are divided into two sections: Summary Statistics and Detailed Statistics. The tables and figures ih the Summary Statistics section of the PSM present a time series of selected petroleum data on a US level. Most time series include preliminary estimates for one month based on the Weekly Petroleum Supply Reporting System; statistics based on the most recent data from the Monthly Petroleum Supply Reporting System (MPSRS); and statistics published in prior issues of the PSM and PSA. The Detailed Statistics tables of the PSM present statistics for the most current month available as well as year-to-date. In most cases, the statistics are presented for several geographic areas - - the United States (50 States and the District of Columbia), five PAD Districts, and 12 Refining Districts. At the US and PAD District level, the total volume and the daily rate of activities are presented. The statistics are developed from monthly survey forms submitted by respondents to the EIA and from data provided firom other sources.

  12. Electric power monthly, July 1994

    Energy Technology Data Exchange (ETDEWEB)

    1994-07-01

    The Electric Power Monthly (EPM) presents monthly electricity statistics. The purpose of this publication is to provide energy decisionmakers with accurate and timely information that may be used in forming various perspectives on electric issues that lie ahead. Data in this report are presented for a wide audience including Congress, Federal and State agencies, the electric utility industry, and the general public. The EIA collected the information in this report to fulfill its data collection and dissemination responsibilities as specified in the Federal Energy Administration Act of 1974 (Public Law 93-275) as amended. The EPM is prepared by the Survey Management Division; Office of Coal, Nuclear, Electric and Alternate Fuels, Energy Information Administration (EIA), Department of Energy. This publication provides monthly statistics at the US, Census division, and State levels for net generation, fossil fuel consumption and stocks, quantity and quality of fossil fuels, cost of fossil fuels, electricity sales, revenue, and average revenue per kilowatthour of electricity sold. Data on net generation, fuel consumption, fuel stocks, quantity and cost of fossil fuels are also displayed for the North American Electric Reliability Council (NERC) regions. Statistics by company and plant are published in the EPM on the capability of new generating units, net generation, fuel consumption, fuel stocks, quantity and quality of fuel, and cost of fossil fuels. Data on quantity, quality, and cost of fossil fuels lag data on net generation, fuel consumption, fuel stocks, electricity sales, and average revenue per kilowatthour by 1 month. This difference in reporting appears in the US, Census division, and State level tables. However, for purposes of comparison, plant-level data are presented for the earlier month.

  13. Contralateral Breast Symmetrisation in Immediate Prosthetic Breast Reconstruction after Unilateral Nipple-Sparing Mastectomy: The Tailored Reduction/Augmentation Mammaplasty

    Directory of Open Access Journals (Sweden)

    Marzia Salgarello

    2015-05-01

    Full Text Available BackgroundIn the literature on nipple-sparing mastectomy (NSM with one-stage immediate implant reconstruction, contralateral symmetrisation has drawn little attention, with many surgeons still performing standard cosmetic mammaplasty procedures. However, standard implant-based mammaplasty usually does not result in proper symmetry with the mastectomy side, especially regarding breast projection, overall shape, and volume distribution.MethodsWe retrospectively reviewed 19 consecutive patients undergoing unilateral NSM with immediate prosthetic reconstruction and contralateral simultaneous symmetrisation by using the tailored reduction/augmentation mammaplasty technique between June 2012 and August 2013.ResultsThe average follow-up time was 13 months (range, 10-24 months. No major complications, such as infection, haematoma, and nipple-areola complex necrosis, were experienced.ConclusionsOur experience suggests that simultaneous contralateral symmetrisation with tailored reduction/augmentation mammaplasty after unilateral immediate implant reconstruction after NSM facilitates durable and pleasant symmetric outcomes.

  14. Immediate loading with fixed full-arch prostheses in the maxilla: Review of the literature

    Science.gov (United States)

    Peñarrocha-Oltra, David; Covani, Ugo; Peñarrocha-Diago, Miguel

    2014-01-01

    Objectives: To critically review the evidence-based literature on immediate loading of implants with fixed full-arch prostheses in the maxilla to determine 1) currently recommended performance criteria and 2) the outcomes that can be expected with this procedure. Study Desing: Studies from 2001 to 2011 on immediate loading with fixed full-arch maxillary prostheses were reviewed. Clinical series with at least 5 patients and 12 months of follow-up were included. Case reports, studies with missing data and repeatedly published studies were excluded. In each study the following was assessed: type of study, implant type, number of patients, number of implants, number of implants per patient, use of post-extraction implants, minimum implant length and diameter, type of prosthesis, time until loading, implant survival rate, prosthesis survival rate, marginal bone loss, complications andmean follow-up time. Criteria for patient selection, implant primary stability and bone regeneration were also studied. Results: Thirteen studies were included, reporting a total of 2484 immediately loaded implants in 365 patients. Currently accepted performance criteria regarding patient and implant selection, and surgical and prosthetic procedures were deduced from the reviewed articles. Implant survival rates went from 87.5% to 100%, prosthesis survival rates from 93.8% to 100% and radiographic marginal bone loss from 0.8 mm to 1.6 mm.No intraoperative complications and only minor prosthetic complications were reported. Conclusions: The literature on immediate loading with fixed full-arch prostheses in the maxilla shows that a successful outcome can be expected if adequate criteria are used to evaluate the patient, choose the implant and perform the surgical and prosthetic treatment. Lack of homogeneity within studies limits the relevance of the conclusions that can be drawn, and more controlled randomized studies are necessary to enable comparison between the immediate and the

  15. Immediate and Sustained Improvement in Behavior and Life Quality by Adenotonsillectomy in Children With Sleep-Disordered Breathing

    Science.gov (United States)

    Jeon, Yung Jin; Song, Jae-Jin; Ahn, Jae-Cheul; Kong, Il Gyu; Kim, Jae-Won; Park, Gyeong-Hun; Won, Tae-Bin

    2016-01-01

    Objectives To investigate longitudinal changes in behavior and quality-of-life (QoL) in children with sleep disordered breathing (SDB) after adenotonsillectomy (AT). Methods This study prospectively enrolled 148 children who underwent AT for SDB. Caregivers filled out Korean attention deficit hyperactivity disorder (ADHD) rating scale (K-ARS) and Korean version of the obstructive sleep apnea-18 (KOSA-18) at preoperative 1 day, postoperative 1 month, and postoperative 6 months. Longitudinal changes in K-ARS and KOSA-18 were evaluated and compared among subgroups. Results Both K-ARS and KOSA-18 scores improved immediately at postoperative 1 month and were maintained at postoperative 6 months. The mean preoperative K-ARS scores of the non-ADHD, ADHD-trait, and overt-ADHD groups showed uniformly immediate and sustained improvements. Also, the mean preoperative KOSA-18 scores of the small, moderate, and large impact groups were significantly improved both at postoperative 1 month and 6 months. The changes in behavior and QoL showed no significant differences with regard to the aforementioned factors. Conclusion After AT, we may expect immediate and sustained improvements in behavior and QoL in children with SDB regardless of preoperative symptom severity. Moreover, by performing AT, improvements in behavior and QoL are expected regardless of sex, age, allergic trait, or concurrent coblation-assisted turbinoplasty. These findings may help our colleague physicians counselling pediatric SDB patients and their caregivers. PMID:27090276

  16. Immediate And Retention Effects Of Teaching Games For Understanding Approach On Basketball Knowledge

    Directory of Open Access Journals (Sweden)

    Olosová Gabriela

    2015-05-01

    Full Text Available Teaching Games for Understanding (TGfU links tactics and skills by emphasizing the appropriate timing and application within the tactical context of the game. It has been linked to the development of enhanced tactical knowledge. The purpose of the study was to determine immediate and delayed effects of TGfU on procedural and declarative knowledge of basketball and to compare it with a technical approach. Experimental group (EG (11 fifth graders + 18 sixth graders was taught by TGfU and a control group (CG (16 fifth graders + 24 sixth graders was taught by a technical approach for 8 weeks in Physical Education (PE classes, both. A written test was constructed to evaluate pupils’ declarative and procedural knowledge of basketball. The test was applied after the intervention to determine immediate effects and 8 months after the intervention to determine retention effects of the experimental programme. Shapiro-Wilk test, Wilcoxon T-test, Man-Whitney U-test were used for statistical analysis of obtained data. Cohen’s d was used to calculate effect size. Generally basketball knowledge was better in EG than in CG after the intervention (p<0.05 what confirms moderate effect size. When declarative and procedural knowledge were analysed separately there was no significant difference between EG and CG. Nevertheless, moderate effect sizes indicate that the data are particularly meaningful in terms of school practice. Retention effects of both approaches were similar. Total knowledge and declarative knowledge were worse after 8 months than immediately after the intervention in both groups (p<0.01. In both groups, there was no significant difference in procedural knowledge between the test written immediately after the intervention and 8 months later. Differences of changes were not significant between the groups.

  17. 77 FR 28415 - Self-Regulatory Organizations; The NASDAQ Stock Market LLC; Notice of Filing and Immediate...

    Science.gov (United States)

    2012-05-14

    ... From the Federal Register Online via the Government Publishing Office SECURITIES AND EXCHANGE COMMISSION Self-Regulatory Organizations; The NASDAQ Stock Market LLC; Notice of Filing and Immediate Effectiveness of Proposed Rule Change To Modify the NASDAQ Co-Location Super High Density Cabinet Monthly Fee May 8, 2012. Pursuant to Section...

  18. Eight month post program completion; change in risk factors for chronic disease amongst participants in a four-month pedometer-based workplace health program

    DEFF Research Database (Denmark)

    Freak-Poli, Rosanne; Wolfe, Rory; Brand, Margaret

    2013-01-01

    measured waist circumference at twelve-months indicated that the significant improvements observed immediately after the health program could not be sustained. Approximately half of those not meeting guidelines for physical activity, waist circumference and blood pressure at baseline, were meeting......OBJECTIVE: To evaluate whether participation in a four-month, pedometer-based, physical activity, workplace health program is associated with long-term sustained improvements in risk factors for type 2 diabetes and cardiovascular disease, eight-months after the completion of the program. DESIGN...... guidelines at twelve-months. CONCLUSIONS: Participation in this four-month, pedometer-based, physical activity, workplace health program was associated with sustained improvements chronic disease risk factors at twelve-months. These results indicate that such programs can have a long-term benefit and thus...

  19. ANG-(1–7) DEFICIENCY AND BAROREFLEX IMPAIRMENT PRECEDE THE ANTENATAL BETAMETHASONE EXPOSURE-INDUCED ELEVATION IN BLOOD PRESSURE

    Science.gov (United States)

    Shaltout, Hossam A.; Rose, James C.; Chappell, Mark C.; Diz, Debra I.

    2014-01-01

    Betamethasone is administered to accelerate lung development and improve survival of premature infants, but may be associated with hypertension later in life. In a sheep model of fetal programming resulting from exposure at 80th day of gestation to Betamethasone (Betaexposed), adult sheep at 6–9 months or 1.8 yrs of age have elevated mean arterial pressure (MAP), and attenuated spontaneous baroreflex sensitivity (sBRS) for control of heart rate compared to age-matched controls, associated with imbalances in angiotensin (Ang) II versus Ang-(1–7) tone. At 6 weeks of age, evoked BRS is already low in the Beta-exposed animals. In this study we assessed the potential contribution of the renin-angiotensin system to the impaired sBRS. Female lambs (6 weeks old) with Beta-exposure in utero had similar MAP to control lambs (78±2 vs 77±2 mm Hg, n = 4–5 per group), but lower sBRS (8±1 vs 16±3 ms/mm Hg; p < 0.05) and impaired heart rate variability (HRV). Peripheral AT1 receptor blockade using candesartan lowered MAP in both groups (~10 mm Hg) and improved sBRS and HRV in Beta-exposed lambs to a level similar to control. AT7 receptor blockade by infusion of D-ala Ang-(1–7) (700 ng/kg/min for 45 min) reduced sBRS 46±10 % in Beta-exposed vs in control lambs (p<0.15) and increased MAP in both groups (~6±2 mm Hg). Our data reveal that Beta-exposure impairs sBRS and HRV at a time point preceding the elevation in MAP via mechanisms involving an imbalance in the Ang II/Ang-(1–7) ratio consistent with a progressive loss in Ang-(1–7) function. PMID:22215705

  20. Angiotensin-(1-7) deficiency and baroreflex impairment precede the antenatal Betamethasone exposure-induced elevation in blood pressure.

    Science.gov (United States)

    Shaltout, Hossam A; Rose, James C; Chappell, Mark C; Diz, Debra I

    2012-02-01

    Betamethasone is administered to accelerate lung development and improve survival of premature infants but may be associated with hypertension later in life. In a sheep model of fetal programming resulting from exposure at day 80 of gestation to Betamethasone (Beta-exposed), adult sheep at 6 to 9 months or 1.8 years of age have elevated mean arterial pressure (MAP) and attenuated spontaneous baroreflex sensitivity (sBRS) for control of heart rate compared to age-matched controls associated with imbalances in angiotensin (Ang) II vs Ang-(1-7) tone. At 6 weeks of age, evoked BRS is already low in the Beta-exposed animals. In this study, we assessed the potential contribution of the renin-angiotensin system to the impaired sBRS. Female lambs (6 weeks old) with Beta exposure in utero had similar MAP to control lambs (78±2 vs 77±2 mm Hg, n=4-5 per group), but lower sBRS (8±1 vs 16±3 ms/mm Hg; P<0.05) and impaired heart rate variability. Peripheral AT1 receptor blockade using candesartan lowered MAP in both groups (≈10 mm Hg) and improved sBRS and heart rate variability in Beta-exposed lambs to a level similar to control. AT7 receptor blockade by infusion of D-ala Ang-(1-7) (700 ng/kg/min for 45 minutes) reduced sBRS 46%±10% in Beta-exposed vs in control lambs (P<0.15) and increased MAP in both groups (≈6±2 mm Hg). Our data reveal that Beta exposure impairs sBRS and heart rate variability at a time point preceding the elevation in MAP via mechanisms involving an imbalance in the Ang II/Ang-(1-7) ratio consistent with a progressive loss in Ang-(1-7) function.

  1. Aseismic Slips Preceding Ruptures Assumed for Anomalous Seismicities and Crustal Deformations

    Science.gov (United States)

    Ogata, Y.

    2007-12-01

    If aseismic slips occurs on a fault or its deeper extension, both seismicity and geodetic records around the source should be affected. Such anomalies are revealed to have occurred during the last several years leading up to the October 2004 Chuetsu Earthquake of M6.8, the March 2007 Noto Peninsula Earthquake of M6.9, and the July 2007 Chuetsu-Oki Earthquake of M6.8, which occurred successively in the near-field, central Japan. Seismic zones of negative and positive increments of the Coulomb failure stress, assuming such slips, show seismic quiescence and activation, respectively, relative to the predicted rate by the ETAS model. These are further supported by transient crustal movement around the source preceding the rupture. Namely, time series of the baseline distance records between a numbers of the permanent GPS stations deviated from the predicted trend, with the trend of different slope that is basically consistent with the horizontal displacements of the stations due to the assumed slips. References Ogata, Y. (2007) Seismicity and geodetic anomalies in a wide area preceding the Niigata-Ken-Chuetsu Earthquake of October 23, 2004, central Japan, J. Geophys. Res. 112, in press.

  2. Increasing valued behaviors precedes reduction in suffering: Findings from a randomized controlled trial using ACT.

    Science.gov (United States)

    Gloster, Andrew T; Klotsche, Jens; Ciarrochi, Joseph; Eifert, Georg; Sonntag, Rainer; Wittchen, Hans-Ulrich; Hoyer, Jürgen

    2017-04-01

    Psychological flexibility theory (PFT) suggests three key processes of change: increases in value-directed behaviors, reduction in struggle with symptoms, and reduction in suffering. We hypothesized that Acceptance and Commitment Therapy (ACT) would change these processes and that increases in valued action and decreases in struggle would precede change in suffering. Data were derived from a randomized clinical trial testing ACT (vs. waitlist) for treatment-resistant patients with primary panic disorder with/without agoraphobia (n = 41). Valued behavior, struggle, and suffering were assessed at each of eight sessions. Valued actions, struggle, and suffering all changed over the course of therapy. Overall changes in struggle and suffering were interdependent whereas changes in valued behavior were largely independent. Levels of valued behaviors influenced subsequent suffering, but the other two variables did not influence subsequent levels of valued action. This finding supports a central tenet of PFT that increased (re-)engagement in valued behaviors precedes reductions in suffering. Possible implications for a better understanding of response and non-response to psychotherapy are discussed. Copyright © 2017 Elsevier Ltd. All rights reserved.

  3. BRIEF HYPOXIA PRECEDING E. COLI BACTEREMIA DOWNREGULATES HEPATIC TNF-α PRODUCTION

    Institute of Scientific and Technical Information of China (English)

    1999-01-01

    Hepatic TNF-α production following gram-negative bacteremia or hypovolemic shock predisposes to acute lung injury. However, TNF-α expression may be modified by the manner in which the hepatic O2 supply is reduced and equally important, its timing relative to bacteremia. Brief secondary hypoxic stress of buffer-perfused rat livers downregulates E. Coli (EC)-induced TNF-α expression whereas low-flow ischemia preceding EC increases subsequent TNF-α production owing to reactive O2 species (ROS). Here we determined whether 30 min of constant-flow hypoxia preceding 109 intraportal EC likewise increases antigenic and bioactive TNF-α protein concentrations during reoxygenation via production of ROS. Multiple groups (n=38) were studied over 180 minutes, circulation antigenic TNF-α decreased in H/R+EC vs. EC controls (1 939±640 vs. 12 407±2 476 μg/L at t=180 min; P<0.01, along with TNF-α bioactivity). TNF-α protein were not restored to control levels in ALLO+H/R+EC. Thus, EC-induced hepatic TNF-α production and export is strongly O2-dependent in intact liver regardless of the generation of ROS or the sequence of bacteremia and modest hypoxic stress.

  4. Stressful life events preceding the onset of depression in Asian patients with major depressive disorder.

    Science.gov (United States)

    Park, Subin; Hatim, Ahmad; Si, Tian-Mei; Jeon, Hong Jin; Srisurapanont, Manit; Bautista, Dianne; Liu, Shen-ing; Chua, Hong Choon; Hong, Jin Pyo

    2015-12-01

    Previous studies have identified the significant role of stressful life events in the onset of depressive episodes. However, there is a paucity of cross-national studies on stressful life events that precede depression. We aimed to compare types of stressful life events associated with the onset of depressive episodes in patients with major depressive disorder (MDD) in five Asian countries. A total of 507 outpatients with MDD were recruited in China (n = 114), South Korea (n = 101), Malaysia (n = 90), Thailand (n = 103) and Taiwan (n = 99). All patients were assessed with the Mini-International Neuropsychiatric Interview and the List of Threatening Experiences. The prevalence of each type of stressful life events was calculated and compared between each country. The type of stressful life event that preceded the onset of a depressive episode differed between patients in China and Taiwan and those in South Korea, Malaysia and Thailand. Patients in China and Taiwan were less likely to report interpersonal relationship problems and occupational/financial problems than patients in South Korea, Malaysia and Thailand. Understanding the nature and basis of culturally determined susceptibilities to specific stressful life events is critical for establishing a policy of depression prevention and providing effective counseling services for depressed patients. © The Author(s) 2015.

  5. Hyperplastic-like colon polyps that preceded microsatellite-unstable adenocarcinomas.

    Science.gov (United States)

    Goldstein, Neal S; Bhanot, Punam; Odish, Eva; Hunter, Susan

    2003-06-01

    We compared hyperplastic-like polyps that preceded microsatellite-unstable adenocarcinomas to incidental hyperplastic polyps to identify distinguishing morphologic criteria. The study group included 106 hyperplastic-like, nonadenomatous, serrated polyps, most from the ascending colon in 91 patients; the control group included 106 rectosigmoid hyperplastic polyps from 106 patients in whom adenocarcinoma did not develop. Study group polyps had an expanded crypt proliferative zone, a serrated architectural outline that became apparent in the basilar crypt regions, basilar crypt dilation, inverted crypts, and a predominance of dysmaturational crypts (crypts with minimal cell maturation). In contrast, control group polyps had a proliferative zone confined to the basal crypt region, serrated architecture that became apparent in the superficial crypt region, rare to no basilar crypt dilation, and rare or no dysmaturational crypts. Hyperplastic-like polyps that preceded microsatellite-unstable adenocarcinomas had a distinctive constellation of morphologic features related to altered and decreased cell function and control that resulted in dysmaturational crypts. Dysmaturation constitutes a range of morphologic alterations, some of which overlap with incidental-type innocuous hyperplastic polyps. The morphologic features described herein provide initial guidelines to identify this potentially important subset of premalignant serrated-like polyps.

  6. Upland rice under no-tillage preceded by crops for soil cover and nitrogen fertilization

    Directory of Open Access Journals (Sweden)

    Edemar Moro

    2013-12-01

    Full Text Available The grain yield of upland rice under no-tillage has been unsatisfactory and one reason could be the nitrate/ammonium balance in the soil. Cover crops and nitrogen fertilization can be used to change the nitrate/ammonium relation in the soil and improve conditions for the development of upland rice in the no-tillage (NT system. The aim was to study the effect of cover crops and nitrogen sources on grain yield of upland rice under no tillage. The study was carried out on the Fazenda Experimental Lageado, in Botucatu, State of São Paulo, Brazil, in an Oxisol area under no-tillage for six years. The experiment was arranged in a randomized block split-plot design with four replications. The plots consisted of six cover crop species (Brachiaria brizantha, B. decumbens, B. humidicola, B. ruziziensis, Pennisetum americanum, and Crotalaria spectabilis and the split-plots of seven forms of N fertilizer management. Millet is the best cover crop to precede upland rice under NT. The best form of N application, as nitrate, is in split rates or total rate at topdressing or an ammonium source with or without a nitrification inhibitor, in split doses. When the cover crops C. spectabilis, B. brizantha, B. decumbens, B. humidicola, and B. ruziziensis preceded rice, they induced the highest grain yield when rice was fertilized with N as ammonium sulfate source + nitrification inhibitor in split rates or total dose at topdressing.

  7. Normalization of cardiac substrate utilization and left ventricular hypertrophy precede functional recovery in heart failure regression.

    Science.gov (United States)

    Byrne, Nikole J; Levasseur, Jody; Sung, Miranda M; Masson, Grant; Boisvenue, Jamie; Young, Martin E; Dyck, Jason R B

    2016-05-15

    Impaired cardiac substrate metabolism plays an important role in heart failure (HF) pathogenesis. Since many of these metabolic changes occur at the transcriptional level of metabolic enzymes, it is possible that this loss of metabolic flexibility is permanent and thus contributes to worsening cardiac function and/or prevents the full regression of HF upon treatment. However, despite the importance of cardiac energetics in HF, it remains unclear whether these metabolic changes can be normalized. In the current study, we investigated whether a reversal of an elevated aortic afterload in mice with severe HF would result in the recovery of cardiac function, substrate metabolism, and transcriptional reprogramming as well as determined the temporal relationship of these changes. Male C57Bl/6 mice were subjected to either Sham or transverse aortic constriction (TAC) surgery to induce HF. After HF development, mice with severe HF (% ejection fraction hypertrophy/HF were returned to values observed in healthy controls. Interestingly, pressure-overload-induced left ventricular hypertrophy (LVH) and cardiac substrate metabolism were restored at 1-week post-DB, which preceded functional recovery. The regression of severe HF is associated with early and dramatic improvements in cardiac energy metabolism and LVH normalization that precede restored cardiac function, suggesting that metabolic and structural improvements may be critical determinants for functional recovery. Published on behalf of the European Society of Cardiology. All rights reserved. © The Author 2016. For permissions please email: journals.permissions@oup.com.

  8. Nonseizure SUDEP: Sudden unexpected death in epilepsy without preceding epileptic seizures.

    Science.gov (United States)

    Lhatoo, Samden D; Nei, Maromi; Raghavan, Manoj; Sperling, Michael; Zonjy, Bilal; Lacuey, Nuria; Devinsky, Orrin

    2016-07-01

    To describe the phenomenology of monitored sudden unexpected death in epilepsy (SUDEP) occurring in the interictal period where death occurs without a seizure preceding it. We report a case series of monitored definite and probable SUDEP where no electroclinical evidence of underlying seizures was found preceding death. Three patients (two definite and one probable) had SUDEP. They had a typical high SUDEP risk profile with longstanding intractable epilepsy and frequent generalized tonic-clonic seizures (GTCS). All patients had varying patterns of respiratory and bradyarrhythmic cardiac dysfunction with profound electroencephalography (EEG) suppression. In two patients, patterns of cardiorespiratory failure were similar to those seen in some patients in the Mortality in Epilepsy Monitoring Units Study (MORTEMUS). SUDEP almost always occur postictally, after GTCS and less commonly after a partial seizure. Monitored SUDEP or near-SUDEP cases without a seizure have not yet been reported in literature. When nonmonitored SUDEP occurs in an ambulatory setting without an overt seizure, the absence of EEG information prevents the exclusion of a subtle seizure. These cases confirm the existence of nonseizure SUDEP; such deaths may not be prevented by seizure detection-based devices. SUDEP risk in patients with epilepsy may constitute a spectrum of susceptibility wherein some are relatively immune, death occurs in others with frequent GTCS with one episode of seizure ultimately proving fatal, while in others still, death may occur even in the absence of a seizure. We emphasize the heterogeneity of SUDEP phenomena. Wiley Periodicals, Inc. © 2016 International League Against Epilepsy.

  9. Left ventricle expands maximally preceding end-diastole. Radionuclide ventriculography study

    Energy Technology Data Exchange (ETDEWEB)

    Horinouchi, Osamu [Kagoshima Univ. (Japan). Faculty of Medicine

    2002-05-01

    It has been considered that left ventricle (LV) expands maximally at the end-diastole. However, is it exactly coincident with this point? This study was aimed to determine whether the maximal expansion of LV coincides with the peak of R wave on electrocardiogram. Thirty-three angina pectoris patients with normal LV motion were examined using radionuclide ventriculography. Data were obtained from every 30 ms backward frame from the peak of R wave. All patients showed the time of maximal expansion preceded the peak of R wave. The intervals from the peak of R wave and the onset of P wave to maximal expansion of LV was 105{+-}29 ms and 88{+-}25 ms, respectively. This period corresponds to the timing of maximal excurtion of mitral valve by atrial contraction, and the centripetal motion of LV without losing its volume before end-diastole may be interpreted on account of the movement of mitral valve toward closure. These findings suggest that LV expands maximally between P and R wave after atrial contraction, preceding the peak of R wave thought conventionally as the end-diastole. (author)

  10. Eye- and feature-based modulation of onset rivalry caused by the preceding stimulus.

    Science.gov (United States)

    Abe, Satoru; Kimura, Eiji; Goryo, Ken

    2011-11-09

    Pre-exposure to a stimulus can modulate initial perceptual dominance experienced in binocular rivalry with brief test stimuli (onset rivalry). This study investigated this modulating effect using both color and pattern stimuli. We confirmed separate contributions of eye- and feature-based suppressions and showed that their relative strength varied with temporal parameters. Eye-based suppression was stronger with a short test duration (10 ms) and shorter ISIs between the preceding and test stimuli. On the other hand, feature-based suppression grew with ISI and was more pronounced with a longer test duration (200 ms). We also investigated the nature of the modulating effect associated with feature-based suppression using chromatic gratings of high luminance contrast. Results revealed that different features of the preceding stimulus (i.e., color and orientation) exerted nearly independent effects on onset rivalry. However, different features shared their fate in competitive interactions for perceptual dominance; when one feature became dominant, the other also dominated. These findings suggest that competitive interactions for perceptual dominance and the modulation of these interactions are mediated at least partially by different mechanisms. Overall, the present findings are consistent with a theoretical view that initial dominance is established through competitive interactions at multiple levels of processing.

  11. Effects of a self-management asthma educational program in Taiwan based on PRECEDE-PROCEED model for parents with asthmatic children.

    Science.gov (United States)

    Chiang, Li-Chi; Huang, Jing-Long; Yeh, Kuo-Wei; Lu, Chang-Ming

    2004-04-01

    This study was conducted to evaluate the comparative effectiveness of two different asthma educational programs. One was self-management asthma education based on the PRECEDE-PROCEED model to change the influential factors based on a previous need assessment study in Taiwan. The other consisted of regular outpatient asthma education. The purposes were: 1) to compare differences in the asthma knowledge, self-efficacy, perceived effectiveness, children's cooperation, doctor-patient communication, and self-management behaviors in the experimental and control groups before education, and 2 weeks, 3 months, and 6 months after education; and 2) to compare differences in drug use, medication utilization, asthma severity, signs/symptoms of asthma, school absenteeism, and exercise ability before education, and 2 weeks, 3 months, and 6 months after education. Parents of asthmatic children were recruited from among outpatients of Chang Gung Children's Hospital, Taoyuan, Taiwan. They were grouped by registration number: those with even numbers were assigned to the experimental group, and those with odd numbers were assigned to the control group. Measurements were collected four times from all parents by means of a questionnaire and chart review. The General Linear Model: Repeat Measurement was used to compare variance differences. The following results were found. 1) Asthma knowledge, self-efficacy, perceived effectiveness, children's cooperation, and self-management behaviors significantly improved after the self-management asthma educational program based on PRECEDE-PROCEED. Except for perceived effectiveness, all variables still had good effectiveness after 6 months of follow-up. The experimental group was better than the control group in knowledge, children's cooperation, and self-management behaviors at the 3-month follow up, as well as in knowledge and children's cooperation at the 6-month follow-up. 2) In both the experimental and control groups, the educational program

  12. Natural Gas Monthly August 1998

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1998-08-01

    The Natural Gas Monthly (NGM) highlights activities, events, and analyses of interest to public and private sector organizations associated with the natural gas industry. Volume and price data are presented each month for natural gas production, distribution, consumption, and interstate pipeline activities. Producer-related activities and underground storage data are also reported. From time to time, the NGM features articles designed to assist readers in using and interpreting natural gas information. Explanatory notes supplement the information found in tables of the report. A description of the data collection surveys that support the NGM is provided. A glossary of the terms used in this report is also provided to assist readers in understanding the data presented in this publication.

  13. Natural gas monthly, August 1996

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-08-01

    This analysis presents the most recent data on natural gas prices, supply, and consumption from the Energy Information Administration (EIA). The presentation of the latest monthly data is followed by an update on natural gas markets. The markets section examines the behavior of daily spot and futures prices based on information from trade press, as well as regional, weekly data on natural gas storage from the American Gas Association (AGA). This {open_quotes}Highlights{close_quotes} closes with a special section comparing and contrasting EIA and AGA storage data on a monthly and regional basis. The regions used are those defined by the AGA for their weekly data collection effort: the Producing Region, the Consuming Region East, and the Consuming Region West. While data on working gas levels have tracked fairly closely between the two data sources, differences have developed recently. The largest difference is in estimates of working gas levels in the East consuming region during the heating season.

  14. Monthly energy review, March 1998

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1998-03-01

    The Monthly Energy Review (MER) presents an overview of the Energy Information Administration`s recent monthly energy statistics. The statistics cover the major activities of U.S. production, consumption, trade, stocks, and prices for petroleum, natural gas, coal, electricity, and nuclear energy. Also included are international energy and thermal and metric conversion factors. Energy production during December 1997 totaled 5.9 quadrillion Btu, a 2.8 percent increase from the level of production during December 1996. Coal production increased 9.5 percent, natural gas production increased 3.9 percent, and production of crude oil and natural gas plant liquids decreased 1.1 percent. All other forms of energy production combined were down 6.9 percent from the level of production during December 1996.

  15. Natural gas monthly, October 1991

    Energy Technology Data Exchange (ETDEWEB)

    1991-11-05

    The Natural Gas Monthly (NGM) is prepared in the Data Operations Branch of the Reserves and Natural Gas Division, Office of Oil and Gas, Energy Information Administration (EIA), US Department of Energy (DOE). The NGM highlights activities, events, and analyses of interest to public and private sector organizations associated with the natural gas industry. Volume and price data are presented each month for natural gas production, distribution, consumption, and interstate pipeline activities. Producer-related activities and underground storage data are also reported. The data in this publication are collected on surveys conducted by the EIA to fulfill its responsibilities for gathering and reporting energy data. Some of the data are collected under the authority of the Federal Energy Regulatory Commission (FERC), an independent commission within the DOE, which has jurisdiction primarily in the regulation of electric utilities and the interstate natural gas industry. Geographic coverage is the 50 States and the District of Columbia. 16 figs., 33 tabs.

  16. Petroleum marketing monthly, September 1994

    Energy Technology Data Exchange (ETDEWEB)

    1994-09-01

    The Petroleum Marketing Monthly (PMM) provides information and statistical data on a variety of crude oils and refined petroleum products. The publication presents statistics on crude oil costs and refined petroleum product sales for use by industry, government, private sector analysts, educational institutions, and consumers. Data on crude oil include the domestic first purchase price, the f.o.b. and landed cost of imported crude oil, and the refiners` acquisition cost of crude oil. Refined petroleum product sales data include motor gasoline, distillates, residuals, aviation fuels, kerosene, and propane. The Petroleum Marketing Division, Office of Oil and Gas, Energy Information Administration ensures the accuracy, quality, and confidentiality of the published data in the Petroleum Marketing Monthly.

  17. Petroleum marketing monthly, June 1994

    Energy Technology Data Exchange (ETDEWEB)

    1994-06-01

    The Petroleum Marketing Monthly (PMM) provides information and statistical data on a variety of crude oils and refined petroleum products. The publication presents statistics on crude oil costs and refined petroleum products sales for use by industry, government, private sector analysts, educational institutions, and consumers. Data on crude oil include the domestic first purchase price, the f.o.b. and landed cost of imported crude oil, and the refiners` acquisition cost of crude oil. Refined petroleum product sales data include motor gasoline, distillates, residuals, aviation fuels, kerosene, and propane. Monthly statistics on purchases of crude oil and sales of petroleum products are presented in five sections: Summary Statistics; Crude Oil Prices; Prices of Petroleum Products; Volumes of Petroleum Products; and Prime Supplier Sales Volumes of Petroleum Products for Local Consumption. The feature article is entitled ``The Second Oxygenated Gasoline Season.`` 7 figs., 50 tabs.

  18. Natural gas monthly, February 1994

    Energy Technology Data Exchange (ETDEWEB)

    1994-02-25

    The NGM highlights activities, events, and analyses of interest to public and private sector organizations associated with the natural gas industry. Volume and price data are presented each month for natural gas production, distribution, consumption, and interstate pipeline activities. Producer-related activities and underground storage data are also reported. The NGM also features articles designed to assist readers in using and interpreting natural gas information.

  19. Monthly energy review, October 1997

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1997-10-01

    This document presents an overview of the Energy Information Administration`s recent monthly energy statistics. The statistics cover the major activities of U.S. production, consumption, trade, stocks, and prices for petroleum, natural gas, coal, electricity, and nuclear energy. Information is also provided for oil and gas resource development. International energy statistics are given for petroleum production, consumption, and stocks, and for nuclear electricity gross generation. 37 figs., 61 tabs.

  20. Laser fusion monthly -- August 1980

    Energy Technology Data Exchange (ETDEWEB)

    Ahlstrom, H.G. [ed.

    1980-08-01

    This report documents the monthly progress for the laser fusion research at Lawrence Livermore National Laboratory. First it gives facilities report for both the Shiva and Argus projects. Topics discussed include; laser system for the Nova Project; the fusion experiments analysis facility; optical/x-ray streak camera; Shiva Dante System temporal response; 2{omega}{sub 0} experiment; and planning for an ICF engineering test facility.

  1. Introducing 'Image of the Month'

    Science.gov (United States)

    Brian, Jones

    2016-04-01

    The Editors of Sedimentary Geology are pleased to announce the establishment of an 'Image of the Month', to appear in each issue of the journal. The idea is to publish outstanding examples of sedimentary features, at all scales, as a means of increasing their visibility and so promoting further discussion and exchange of ideas within the community. The image could be at the scale of satellite image, aerial photograph, outcrop, specimen or thin section.

  2. Monthly energy review, December 1995

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1995-12-21

    This publication presents an overview of EIA`s recent monthly energy statistics. The statistics cover the major activities of US production, consumption, trade, stocks, and prices for petroleum, natural gas, coal, electricity, and nuclear energy. Also included are international energy and thermal and metric conversion factors. An energy preview of alternative fuel providers vehicle fleet surveys is included. The publication is intended for use by members of Congress, Federal and State agencies, energy analysts, and the general public.

  3. Electric power monthly, May 1996

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-05-01

    This publication presents monthly electricity statistics for a wide audience including Congress, Federal and Stage agencies, the electric utility industry, and the general public. Purpose is to provide energy decisionmakers with accurate and timely information that may be used in forming various perspectives on electric issues that lie ahead. EIA collected the information to fulfill its data collection and dissemination responsibilities in Federal Energy Administration Act of 1974 (Public Law 93-275) as amended.

  4. Electric Power monthly, November 1996

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-11-01

    This publication presents monthly electricity statistics for a wide audience including Congress, Federal and state agencies, the electric utility industry, and the general public. Purpose is to provide energy decisionmakers with accurate and timely information that may be used in forming various perspectives on electric issues that lie ahead. EIA collected the information in this report to fulfill its data collection and dissemination responsibilities as specified in the Federal Energy Administration Act of 1974 (Public Law 93-275) as amended.

  5. Natural gas monthly, March 1998

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1998-03-01

    The March 1998 edition of the Natural Gas Monthly highlights activities, events, and analyses associated with the natural gas industry. Volume and price data are presented for natural gas production, distribution, consumption, and interstate pipeline activities. Producer-related activities and underground storage data are also reported. This report also features an article on the correction of errors in the drilling activity estimates series, and in-depth drilling activity data. 6 figs., 28 tabs.

  6. Natural gas monthly, March 1998

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1998-03-01

    The March 1998 edition of the Natural Gas Monthly highlights activities, events, and analyses associated with the natural gas industry. Volume and price data are presented for natural gas production, distribution, consumption, and interstate pipeline activities. Producer-related activities and underground storage data are also reported. This report also features an article on the correction of errors in the drilling activity estimates series, and in-depth drilling activity data. 6 figs., 28 tabs.

  7. Immediate postpartum levonorgestrel intrauterine device insertion and breast-feeding outcomes: a noninferiority randomized controlled trial.

    Science.gov (United States)

    Turok, David K; Leeman, Lawrence; Sanders, Jessica N; Thaxton, Lauren; Eggebroten, Jennifer L; Yonke, Nicole; Bullock, Holly; Singh, Rameet; Gawron, Lori M; Espey, Eve

    2017-08-23

    Immediate postpartum levonorgestrel intrauterine device insertion is increasing in frequency in the United States, but few studies have investigated the effect of early placement on breast-feeding outcomes. This study examined the effect of immediate vs delayed postpartum levonorgestrel intrauterine device insertion on breast-feeding outcomes. We conducted this noninferiority randomized controlled trial at the University of Utah and the University of New Mexico Health Sciences Centers from February 2014 through March 2016. Eligible women were pregnant and planned to breast-feed, spoke English or Spanish, were aged 18-40 years, and desired a levonorgestrel intrauterine device. Enrolled women were randomized 1:1 to immediate postpartum insertion or delayed insertion at 4-12 weeks' postpartum. Prespecified exclusion criteria included delivery <37.0 weeks' gestational age, chorioamnionitis, postpartum hemorrhage, contraindications to levonorgestrel intrauterine device insertion, and medical complications of pregnancy that could affect breast-feeding. We conducted per-protocol analysis as the primary approach, as it is considered the standard for noninferiority studies; we also report the alternative intent-to-treat analysis. We powered the study for the primary outcome, breast-feeding continuation at 8 weeks, to detect a 15% noninferiority margin between groups, requiring 132 participants in each arm. The secondary study outcome, time to lactogenesis, used a validated measure, and was analyzed by survival analysis and log rank test. We followed up participants for ongoing data collection for 6 months. Only the data analysis team was blinded to the intervention. We met the enrollment target with 319 participants, but lost 34 prior to randomization and excluded an additional 26 for medical complications prior to delivery. The final analytic sample included 132 in the immediate group and 127 in the delayed group. Report of any breast-feeding at 8 weeks in the immediate

  8. Electric power monthly, October 1993

    Energy Technology Data Exchange (ETDEWEB)

    1993-10-20

    The Electric Power Monthly (EPM) presents monthly electricity statistics. The purpose of this publication is to provide energy decisionmakers with accurate and timely information that may be used in forming various perspectives on electric issues that lie ahead. Data in this report are presented for a wide audience including Congress, Federal and State agencies, the electric utility industry, and the general public. The EIA collected the information in this report to fulfill its data collection and dissemination responsibilities as specified in the Federal Energy Administration Act of 1974 (Public Law 93-275) as amended. This publication provides monthly statistics at the US, Census division, and State levels for net generation, fossil fuel consumption and stocks, quantity and quality of fossil fuels, cost of fossil fuels, electricity sales, revenue, and average revenue per kilowatthour of electricity sold. Data on net generation, fuel consumption, fuel stocks, quantity and cost of fossil fuels are also displayed for the North American Electric Reliability Council (NERC) regions. Statistics by company and plant are published in the EPM on the capability of new generating units, net generation, fuel consumption, fuel stocks, quantity and quality of fuel, and cost of fossil fuels.

  9. Natural gas monthly, March 1999

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1999-03-01

    This issue of the Natural Gas Monthly contains estimates for March 1999 for many natural gas data series at the national level. Estimates of national natural gas prices are available through December 1998 for most series. Highlights of the data contained in this issue are listed below. Preliminary data indicate that the national average wellhead price for 1998 declined to 16% from the previous year ($1.96 compared to $2.32 per thousand cubic feet). At the end of March, the end of the 1998--1999 heating season, the level of working gas in underground natural gas storage facilities is estimated to be 1,354 billion cubic feet, 169 billion cubic feet higher than at the end of March 1998. Gas consumption during the first 3 months of 1999 is estimated to have been 179 billion cubic feet higher than in the same period in 1998. Most of this increase (133 billion cubic feet) occurred in the residential sector due to the cooler temperatures in January and February compared to the same months last year. According to the National Weather Service, heating degree days in January 1999 were 15% greater than the previous year while February recorded a 5% increase.

  10. Electric power monthly, February 1994

    Energy Technology Data Exchange (ETDEWEB)

    1994-02-16

    The Electric Power Monthly (EMP) presents monthly electricity statistics. The purpose of this publication is to provide energy decisionmakers with accurate and timely information that may be used in forming various perspectives on electric issues that lie ahead. Data in this report are presented for a wide audience including Congress, Federal and State agencies, the electric utility industry, and the general public. The EIA collected the information in this report to fulfill its data collection and dissemination responsibilities as specified in the Federal Energy Administration Act of 1974 (Public Law 93-275) as amended. This publication provides monthly statistics at the US, Census division, and State levels for net generation, fossil fuel consumption and stocks, quantity and quality of fossil fuels, cost of electricity sales, revenue, and average revenue per kilowatthour of electricity sold. Data on net generation, fuel consumption, fuel stocks, quantity and cost of fossil fuels are also displayed for the North American Electric Reliability Council (NERC) regions. Statistics by company and plant are published in the EPM on the capability of new generating units, net generation, fuel consumption, fuel stocks, quantity and quality of fuel, and cost of fossil fuels.

  11. Electric power monthly, January 1994

    Energy Technology Data Exchange (ETDEWEB)

    1994-01-26

    The Electric Power Monthly (EPM) presents monthly electricity statistics. The purpose of this publication is to provide energy decisionmakers with accurate and timely information that may be used in forming various perspectives on electric issues that lie ahead. Data in this report are presented for a wide audience including Congress, Federal and State agencies, the electric utility industry, and the general public. The EIA collected the information in this report to fulfill its data collection and dissemination responsibilities as specified in the Federal Energy Administration Act of 1974 (Public Law 93-275) as amended. This publication provides monthly statistics at the US Census division, and State levels for net generation, fossil fuel consumption and stocks, quantity and quality of fossil fuels, cost of fossil fuels, electricity sales, revenue, and average revenue per kilowatthour of electricity sold. Data on net generation, fuel consumption, fuel stocks, quantity and cost of fossil fuels are also displayed for the North American Electric Reliability Council (NERC) regions. Statistics by company and plant are published in the EPM on the capability of new generating units, net generation, fuel consumption, fuel stocks, quantity and quality of fuel, and cost of fossil fuels.

  12. Electric Power Monthly, June 1990

    Energy Technology Data Exchange (ETDEWEB)

    1990-09-13

    The EPM is prepared by the Electric Power Division; Office of Coal, Nuclear, Electric and Alternate Fuels, Energy Information Administration (EIA), Department of Energy. This publication provides monthly statistics at the national, Census division, and State levels for net generation, fuel consumption, fuel stocks, quantity and quality of fuel, electricity sales, and average revenue per kilowatthour of electricity sold. Data on net generation are also displayed at the North American Electric Reliability Council (NERC) region level. Additionally, company and plant level information are published in the EPM on capability of new plants, net generation, fuel consumption, fuel stocks, quantity and quality of fuel, and cost of fuel. Quantity, quality, and cost of fuel data lag the net generation, fuel consumption, fuel stocks, electricity sales, and average revenue per kilowatthour data by 1 month. This difference in reporting appears in the national, Census division, and State level tables. However, at the plant level, all statistics presented are for the earlier month for the purpose of comparison. 40 tabs.

  13. Digital immediate dentures treatment: A clinical report of two patients.

    Science.gov (United States)

    Neumeier, Toni Tien; Neumeier, Harold

    2016-09-01

    The use of computer-aided engineering (CAE) and computer-aided design and computer-aided manufacturing (CAD-CAM) technology to fabricate complete dentures was introduced in 2011. Clinical procedures for digital immediate dentures can be identical to those for conventional immediate dentures and can be simplified by leaving all remaining dentition until the time of extraction and denture placement. Through the digital process, a single digital design and a definitive digital record are created which can be used to fabricate the immediate digital denture and surgical reduction guide for alveoloplasty. Digital immediate dentures can be relined using the same process as for conventional dentures. The definitive digital dentures can be fabricated with a reline impression and new centric relation record, using the existing digital immediate denture without additional clinical procedures. Providing patients with digital immediate dentures is a viable trend.

  14. Microwave Tissue Soldering for Immediate Wound Closure

    Science.gov (United States)

    Arndt, G. Dickey; Ngo, Phong H.; Phan, Chau T.; Byerly, Diane; Dusl, John; Sognier, Marguerite A.; Carl, James

    2011-01-01

    A novel approach for the immediate sealing of traumatic wounds is under development. A portable microwave generator and handheld antenna are used to seal wounds, binding the edges of the wound together using a biodegradable protein sealant or solder. This method could be used for repairing wounds in emergency settings by restoring the wound surface to its original strength within minutes. This technique could also be utilized for surgical purposes involving solid visceral organs (i.e., liver, spleen, and kidney) that currently do not respond well to ordinary surgical procedures. A miniaturized microwave generator and a handheld antenna are used to deliver microwave energy to the protein solder, which is applied to the wound. The antenna can be of several alternative designs optimized for placement either in contact with or in proximity to the protein solder covering the wound. In either case, optimization of the design includes the matching of impedances to maximize the energy delivered to the protein solder and wound at a chosen frequency. For certain applications, an antenna could be designed that would emit power only when it is in direct contact with the wound. The optimum frequency or frequencies for a specific application would depend on the required depth of penetration of the microwave energy. In fact, a computational simulation for each specific application could be performed, which would then match the characteristics of the antenna with the protein solder and tissue to best effect wound closure. An additional area of interest with potential benefit that remains to be validated is whether microwave energy can effectively kill bacteria in and around the wound. Thus, this may be an efficient method for simultaneously sterilizing and closing wounds.

  15. Factors influencing ridge alterations following immediate implant placement into extraction sockets.

    Science.gov (United States)

    Ferrus, Jorge; Cecchinato, Denis; Pjetursson, E Bjarni; Lang, Niklaus P; Sanz, Mariano; Lindhe, Jan

    2010-01-01

    To identify factors that may influence ridge alterations occurring at the buccal aspect of the extraction site following immediate implant placement. In 93 subjects, single-tooth implants were placed immediately into extraction sockets in the maxilla (tooth locations 15-25). A series of measurements describing the extraction site were made immediately after implant installation and at re-entry, 16 weeks later. The implant sites were stratified according to four factors: (i) implant location (anterior/posterior), (ii) cause of tooth extraction (periodontitis/non-periodontitis), (iii) thickness of the buccal bone walls ( 1 mm) and (iv) the dimension of the horizontal buccal gap ( 1 mm). (i) The location where the implant was placed (anterior/posterior) as well as (ii) the thickness of the buccal bone crest and (iii) the size of the horizontal buccal gap significantly influenced the amount of hard tissue alteration that occurred during a 4-month period of healing. At implant sites in the premolar segment, the fill of the horizontal gap was more pronounced than in the incisor-canine segment, while the vertical crest reduction was significantly smaller. Furthermore, at sites where the buccal bone wall was thick (>1 mm) and where the horizontal gap was large (>1 mm), the degree of gap fill was substantial. The thickness of the buccal bone wall as well as the dimension of the horizontal gap influenced the hard tissue alterations that occur following immediate implant placement into extraction sockets.

  16. A feasibility study of immediate versus deferred antiretroviral therapy in children with HIV infection

    Directory of Open Access Journals (Sweden)

    Ubolyam Sasiwimol

    2008-10-01

    Full Text Available Abstract Objective To evaluate the feasibility of a large immediate versus deferred antiretroviral therapy (ART study in children. Methods We conducted an open-label pilot randomized clinical trial study in 43 Thai children with CD4 15 to 24% of starting generic AZT/3TC/NVP immediately (Arm 1 or deferring until CD4 Results Recruitment took 15 months. Twenty-six of 69 (37.7% were not eligible due mainly to low CD4%. Twenty four and 19 were randomized to arms 1 and 2 respectively. All accepted the randomized arm; however, 3 in arm 1 stopped ART and 1 in arm 2 refused to start ART. Ten/19 (53% in arm 2 started ART. At baseline, median age was 4.8 yrs, CDC A:B were 36:7, median CD4 was 19% and viral load was 4.8 log. All in arm 1 and 17/19 in arm 2 completed the study (median of 134 weeks. No one had AIDS or death. Four in immediate arm had tuberculosis. Once started on ART, deferred arm children achieved similar CD4 and viral load response as the immediate arm. Adverse events were similar between arms. The deferred arm had a 26% ART saving. Conclusion Almost 40% of children were not eligible due mainly to low CD4% but adherence to randomized treatment and retention in trial were excellent. A larger study to evaluate when to start ART is feasible.

  17. Selected pictures of the month

    CERN Multimedia

    Claudia Marcelloni de Oliveira

    View of a single MDT Big Wheel (on side A in UX15 cavern) taken during its last movement immediately after being assembled and just before being connected to the neighbouring TGC1 wheel. Assembly work on the Cathode Strip Chambers on Small Wheel C in building 190. Connecting the services for the Cathode Strip Chambers. The installation of the optical fibers for the readout of the Cathode Strip Chambers on Small Weel C by the Irvine group. Best from our archives: View of the End Cap Calorimeter and TGC big wheel from the Cryostat side A of ATLAS cavern taken on 22 May 2007. The picture above was taken from the platform in the middle, between the Cryostat and the End-Cap. Muriel hopes you all had a great vacation. She herself had a wonderful time sailing in Galicia (North Western Spain). She can be seen here wearing the traditional dress offered to her by "Los Amigos de las Dornas" (Friends of the Dornas -traditional sailing boats used for fishing) - when she became ...

  18. Immediate bleeding complications in dental implants: a systematic review

    OpenAIRE

    Balaguer Martí, José Carlos; Peñarrocha Oltra, David; Balaguer Martínez, José; Peñarrocha Diago, Miguel

    2015-01-01

    Objective: A review is made of the immediate or immediate postoperative bleeding complications in dental implants, with a view to identifying the areas of greatest bleeding risk, the causes of bleeding, the length of the implants associated with bleeding, the most frequently implicated blood vessels, and the treatments used to resolve these complications. Material and Methods: A Medline (PubMed) and Embase search was made of articles on immediate bleeding complications in dental implants publ...

  19. Immediate primary anastomosis for isolated oesophageal atresia: A single-centre experience

    Directory of Open Access Journals (Sweden)

    Ibrahim Uygun

    2015-01-01

    Full Text Available Background: Isolated oesophageal atresia without tracheo-oesophageal fistula represents a major challenge for most paediatric surgeons. Here, we present our experience with six neonates with isolated oesophageal atresia who successfully underwent immediate primary anastomosis using multiple Livaditis circular myotomy. Materials and Methods: All six neonates were gross type A isolated oesophageal atresia (6%, from among 102 neonates with oesophageal atresia, treated between January 2009 and December 2013. Five neonates were female; one was male. The mean birth weight was 2300 (range 1700-3100 g. Results: All six neonates successfully underwent immediate primary anastomosis using multiple myotomies (mean 3; range 2-4 within 10 (median 3 days after birth. The gap under traction ranged from 6 to 7 cm. One neonate died of a major cardiac anomaly. Another neonate was lost to follow-up after being well for 3 months. Three anastomotic strictures were treated with balloon dilatation, and four anastomotic leaks were treated conservatively. The mean duration of follow-up was 33 months. Conclusions: To treat isolated oesophageal atresia, an immediate primary anastomosis can be achieved using multiple myotomies. Although, this approach is associated with high complication rates, as are other similar approaches, these complications can be overcome.

  20. Precursory TEC enhancement immediately before the 2011 Tohoku-Oki earthquake

    Science.gov (United States)

    Heki, K.

    2011-12-01

    Earthquakes are often preceded by electromagnetic precursors, and we have been searching for them in, e.g. electric currents in the ground and propagation anomalies of radio waves. Here I report that a positive anomaly of ionospheric Total Electron Content (TEC) appeared immediately before the 2011 Tohoku-Oki earthquake (Mw9.0). Microwave signals from GPS satellites experience delays inversely proportional to the square of the frequency as they propagate through the ionosphere. By monitoring the differences of the L1 and L2 carrier phases with the dense GPS array, we can infer 2-D distribution of TEC above Japan. Coseismic vertical crustal movements excite acoustic waves, and they arrive at the ionosphere in ~10 minutes and cause coseismic ionospheric disturbances (CID). Raw TEC time series on March 11 show such CID in addition to slow background variations due to the changes in elevation and diurnal variation of vertical TEC (VTEC). We modeled the VTEC over the studied time window of ~5 hours with a cubic polynomial of time, and defined the departure from the model as TEC anomalies. Positive anomaly was found to start ~40 minutes before the earthquake in data of four GPS satellites 9, 15, 26, 27. The anomaly was larger at points closer to the epicenter, and reached ~1/10 of the background TEC immediately before the earthquake. The anomaly disappeared after the passage of CID. TEC increases often occur irrespective of earthquakes. For example, enhanced UV flux due to solar flares causes sudden increase of TEC. This, however, occurs on the whole sun-lit hemisphere, and never localizes above the focal region. Large-scale traveling ionospheric disturbances (LSTID) excited in the auroral oval often propagate southward and reach Japan. This can be distinguished by carefully observing their movements. I analyzed the TEC time series of satellite 15 observed at 93009 over 120 days from January to April, 2011. The precursory anomaly on March 11 showed the largest departure

  1. [PRIMARY STUDY ON IMPLANT COVERAGE WITH LOCAL SOFT TISSUE IN IMMEDIATE IMPLANT-BASED BREAST RECONSTRUCTION].

    Science.gov (United States)

    Li, Guangxue; Mu, Lan; Liu, Yan; Yang, Kai; Peng, Zhe; Bi, Ye

    2016-03-01

    To explore the method of implant coverage with local soft tissue in immediate implant-based breast reconstruction and to evaluate the early effectiveness. Between April 2014 and August 2015, 11 patients with breast cancer underwent immediate breast reconstruction with implants after mastectomy, and the clinical data were reviewed retrospectively. The age ranged 29-48 years (mean, 36 years). The disease duration was from 7 days to 12 months (median, 3 months). According to tumor staging, 3 cases were rated as T(is)N0M0, 4 cases as T1N0M0, and 4 cases as T2N0M0. The implants were covered with local soft tissue according to the volume of mastectomy and contralateral breast size, including pectoralis major myocutaneous flaps with inframammary adipofasical flaps (3 cases), with serratus anterior fascial flap (5 cases), with rectus sheath fascial flap (1 case), and with serratus anterior fascial flap and rectus sheath fascial flap (2 cases). The size of pectoralis major myocutaneous flaps ranged from 15 cm x 9 cm to 20 cm x 15 cm, and the serratus anterior fascial flaps from 10 cm x 8 cm to 15 cm x 10 cm, and the rectus sheath fascial flap from 8 cm x 6 cm to 10 cm x 8 cm. One patient had partial nipple necrosis postoperatively and was cured, and no other postoperative complications of hematoma, infection, or implant exposure was found. The patients were followed up 4-13 months (median, 8 months). The reconstructive outcomes were excellent in 10 cases and good in 1 case, with an excellent and good rate of 100%. During follow-up, no rupture or exposure of the implant was observed; capsular contracture (Baker grade II) occurred in 1 case. Adequate coverage of implants with different local soft tissue flaps can achieve satisfactory early effectiveness in immediate implant-based breast reconstruction after mastectomy.

  2. Monthly forecasting of agricultural pests in Switzerland

    Science.gov (United States)

    Hirschi, M.; Dubrovsky, M.; Spirig, C.; Samietz, J.; Calanca, P.; Weigel, A. P.; Fischer, A. M.; Rotach, M. W.

    2012-04-01

    Given the repercussions of pests and diseases on agricultural production, detailed forecasting tools have been developed to simulate the degree of infestation depending on actual weather conditions. The life cycle of pests is most successfully predicted if the micro-climate of the immediate environment (habitat) of the causative organisms can be simulated. Sub-seasonal pest forecasts therefore require weather information for the relevant habitats and the appropriate time scale. The pest forecasting system SOPRA (www.sopra.info) currently in operation in Switzerland relies on such detailed weather information, using hourly weather observations up to the day the forecast is issued, but only a climatology for the forecasting period. Here, we aim at improving the skill of SOPRA forecasts by transforming the weekly information provided by ECMWF monthly forecasts (MOFCs) into hourly weather series as required for the prediction of upcoming life phases of the codling moth, the major insect pest in apple orchards worldwide. Due to the probabilistic nature of operational monthly forecasts and the limited spatial and temporal resolution, their information needs to be post-processed for use in a pest model. In this study, we developed a statistical downscaling approach for MOFCs that includes the following steps: (i) application of a stochastic weather generator to generate a large pool of daily weather series consistent with the climate at a specific location, (ii) a subsequent re-sampling of weather series from this pool to optimally represent the evolution of the weekly MOFC anomalies, and (iii) a final extension to hourly weather series suitable for the pest forecasting model. Results show a clear improvement in the forecast skill of occurrences of upcoming codling moth life phases when incorporating MOFCs as compared to the operational pest forecasting system. This is true both in terms of root mean squared errors and of the continuous rank probability scores of the

  3. Foreshock Patterns Preceding Great Earthquakes in the Subduction Zone of Chile

    Science.gov (United States)

    Papadopoulos, G. A.; Minadakis, G.

    2016-10-01

    Foreshock activity is considered as one of the most promising precursory changes for the main shock prediction in the short term. Averaging over several foreshock sequences has shown that foreshocks are characterized by distinct 3D patterns: their epicenters move towards the main shock epicenter, event count accelerates, and b-value drops. However, these space-time-size patterns were verified so far only in a very few individual cases mainly due to inadequate seismicity catalogue data. We have investigated 3D foreshock patterns before the M w 8.8 Maule in 27 February 2010, M w 8.1 Iquique in 1 April 2014, and M w 8.4 Illapel in 16 September 2015 great earthquakes in the Chile subduction zone. To avoid biased results, no a priori spatiotemporal definitions of foreshocks were inserted. The procedure was based on pattern recognition from statistically significant seismicity changes in the three domains. The pattern recognition in one domain was independent of the pattern recognition in another domain. We found and verified with two independent catalogue data sets (CSN, IPOC) that within a critical area of ca. 65 km from the main shock epicenter, the 2014 event was preceded by distinct foreshock 3D patterns. A nearly weak foreshock stage (20 January-14 March 2014) was followed by a main-strong stage (15 March-1 April 2014) highly significant in all domains, although foreshock activity slightly decreased in about the last 5 days. Seismic moment release also accelerated in the last stage due to the occurrence of a cluster of very strong foreshock events. Foreshock activity very likely occurred in the hanging-wall fault domain on the South American Plate overriding Nazca Plate. The 2014 foreshock activity was quite similar to the one preceding the 6 Apr. 2009 L' Aquila (Italy) M w 6.3 earthquake associated with normal faulting. Using the 2014 earthquake as a reference event, we observed that similar foreshock 3D patterns preceded the 2010 and 2015 earthquakes within

  4. Astrocytosis precedes amyloid plaque deposition in Alzheimer APPswe transgenic mouse brain: a correlative positron emission tomography and in vitro imaging study

    Energy Technology Data Exchange (ETDEWEB)

    Rodriguez-Vieitez, Elena; Ni, Ruiqing; Voytenko, Larysa; Marutle, Amelia [Karolinska Institutet, Division of Translational Alzheimer Neurobiology, Centre for Alzheimer Research, Department of Neurobiology, Care Sciences and Society, Stockholm (Sweden); Gulyas, Balazs; Halldin, Christer [Karolinska Institutet, Centre for Psychiatric Research, Department of Clinical Neuroscience, Stockholm (Sweden); Nanyang Technological University, NTU - Imperial College, Lee Kong Chian School of Medicine, Singapore (Singapore); Toth, Miklos; Haeggkvist, Jenny [Karolinska Institutet, Centre for Psychiatric Research, Department of Clinical Neuroscience, Stockholm (Sweden); Nordberg, Agneta [Karolinska Institutet, Division of Translational Alzheimer Neurobiology, Centre for Alzheimer Research, Department of Neurobiology, Care Sciences and Society, Stockholm (Sweden); Karolinska University Hospital Huddinge, Department of Geriatric Medicine, Stockholm (Sweden)

    2015-04-17

    GFAP{sup +} reactive astrocytes in the hippocampus at 18-24 months than at 6 months in APPswe mice. The findings provide further in vivo evidence that astrocytosis occurs early in AD, preceding Aβ plaque deposition. (orig.)

  5. The clinical significance of immediate symptom responses to manual therapy treatment for neck pain: observational secondary data analysis of a randomized trial.

    Science.gov (United States)

    Trott, Caelum A; Ruiz Aguila, Maria Eliza; Leaver, Andrew M

    2014-12-01

    The objective was to explore aspects of symptom responses to manual therapy treatment for neck pain. An observational secondary data analysis of a randomized trial was conducted. 181 participants seeking care from a physiotherapist or chiropractor for a new episode of neck pain were included. Outcome variables included recovery-time and participant-perceived effect of treatment (GPE) at 3-months. There was a significant reduction of ≥1.4 points (95%CI 1.2-1.5) in pre- and post-treatment pain scores at each occasion of treatment. There was also small but significant increases in pain of ≤0.7 points (95%CI 0.4-1.0) between each treatment session, without regression to the preceding pre-treatment level. The relationships between immediate post-treatment effects and longer-term outcomes were explored using multivariate regression analyses. There was significant univariate association between recovery time and cumulative post-treatment changes in pain from the second, third and fourth (Exp(B) = 1.2) treatment sessions, as well as the presence of post-treatment headache (Exp(B) = 0.7) and other minor adverse symptoms (Exp(B) = 0.6). There was significant univariate association between GPE at 3-months and cumulative pain responses from first (B = 0.2), second (B = 0.3), third (B = 0.3) and fourth (B = 0.4) treatment sessions. The change in pain after session 1 was independently associated with GPE (B = 0.2). There was a consistently significant difference of ≥0.7 points (95%CI 0.43-0.89) in the different methods of reporting pain. Our results showed that manual therapy for neck pain involves a "two-steps forward, one-step back" recovery pattern. Whilst minor adverse events are undesirable, they do not seem to be significantly associated with long-term recovery.

  6. Petroleum marketing monthly, November 1993

    Energy Technology Data Exchange (ETDEWEB)

    1993-11-09

    The Petroleum Marketing Monthly (PMM) is designed to give information and statistical data about a variety of crude oils and refined petroleum products. The publication provides statistics on crude oil costs and refined petroleum products sales for use by industry, government, private sector analysts, educational institutions, and consumers. Data on crude oil include the domestic first purchase price, the f.o.b. and landed costs of imported crude oil, and the refiner`s acquisition cost of crude oil. Sales data for motor gasoline, distillates, residuals, aviation fuels, kerosene, and propane are presented.

  7. Monthly energy review, September 1997

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1997-09-01

    This publication presents an overview of the Energy Information Administration`s recent monthly energy statistics. The statistics cover the major activities of U.S. production, consumption, trade, stocks, and prices for petroleum, natural gas, coal, electricity, and nuclear energy. Information is also provided on international energy, including petroleum production, consumption, and stocks and nuclear electricity gross generation. This issues provides a brief industry overview and a detailed analysis of the spring 1996 gasoline price runup, crude oil supply issues, U.S. crude oil imports, petroleum stocks, futures markets, refining cash margin trends, and the financial performance of U.S. refining and marketing firms. 37 figs., 73 tabs.

  8. Petroleum supply monthly: December 1993

    Energy Technology Data Exchange (ETDEWEB)

    1993-12-01

    Data are presented which describe the supply and disposition of petroleum products in the United States and major U.S. geographic regions. The data series describe production, imports and exports, inter-Petroleum Administration for Defense (PAD) District movements, and inventories by the primary suppliers of petroleum products in the United States. Data are presented in two sections: Summary Statistics, presenting a time series of selected petroleum data on a U.S. level, and Detailed Statistics, presenting statistics for the most current month available as well as year to date.

  9. Petroleum marketing monthly, October 1993

    Energy Technology Data Exchange (ETDEWEB)

    1993-10-07

    The Petroleum Marketing Monthly (PMM) is designed to give information and statistical data about a variety of crude oils and refined petroleum products. The publication provides statistics on crude oil and refined petroleum products sales for use by industry, government, private sector analysts, educational institutions, and consumers. Data on crude oil include the domestic first purchase prices, the f.o b. and landed cost of imported crude oil, and the refiners` acquisition cost of crude oil. Sales data for motor gasoline, distillates residuals, aviation fuels, kerosene, and propane are presented.

  10. Petroleum marketing monthly, August 1990

    Energy Technology Data Exchange (ETDEWEB)

    1990-11-07

    The Petroleum Marketing Monthly (PMM) is designed to give information and statistical data about a variety of crude oils and refined petroleum products. The publication provides statistics on crude oil costs and refined petroleum products sales for use by industry, government, private sector analysts, educational institutions, and consumers. Data on crude oil include the domestic first purchase price, the f.o.b. and landed cost of imported crude oil, and the refiners' acquisition cost of crude oil. Sales data for motor gasoline, distillates, residuals, aviation fuels, kerosene, and propane are presented. 12 figs., 49 tabs.

  11. Petroleum supply monthly, April 1994

    Energy Technology Data Exchange (ETDEWEB)

    1994-04-01

    Data presented in the Petroleum Supply Monthly (PSM) describe the supply and disposition of petroleum products in the United States and major US geographical regions. The data series describe production, imports and exports, inter-Petroleum Administration for Defense (PAD) District movements, and inventories by the primary suppliers of petroleum products in the US. The reporting universe includes those petroleum sectors in primary supply. Included are: petroleum refiners, motor gasoline blenders, operators of natural gas processing plants and fractionators, inter-PAD transporters, importers, and major inventory holders of petroleum products and crude oil. When aggregated, the data reported by these sectors approximately represent the consumption of petroleum products in the US.

  12. Petroleum marketing monthly, February 1994

    Energy Technology Data Exchange (ETDEWEB)

    1994-02-25

    The Petroleum Marketing Monthly is designed to give information and statistical data about a variety of crude oils and refined petroleum products. The publication provides statistics on crude oil costs and refined petroleum products sales for use by industry, government, private sector analysts, educational institutions, and consumers. Data on crude oil include the domestic first purchase price, the f.o.b. and landed cost of imported crude oil, and the refiner`s acquisition cost of crude oil. Sales data for motor gasoline, distillates, residuals, aviation fuels, kerosene, and propane are presented.

  13. Petroleum marketing monthly, August 1993

    Energy Technology Data Exchange (ETDEWEB)

    1993-08-10

    The Petroleum Marketing Monthly (PMM) is designed to give information and statistical data about a variety of crude oils and refined petroleum products. The publication provides statistics on crude oil costs and refined petroleum products sales for use by industry, government, private sector analysts, educational institutions, and consumers. Data on crude oil include the domestic first purchase price, the f.o.b. and landed cost of imported crude oil, and the refiners` acquisition cost of crude oil. Sales data for motor gasoline, distillates, residuals, aviation fuels, kerosene, and propane are presented.

  14. Restenosis 3 months after successful percutaneous aortic valvoplasty. A clinicopathological report

    NARCIS (Netherlands)

    P.W.J.C. Serruys (Patrick); C. di Mario (Carlo); C.E. Essed

    1987-01-01

    textabstractA 76-year-old man with severe, calcific aortic stenosis experienced recurrence of symptoms 3 months after a successful percutaneous aortic valvoplasty. Echo Doppler revealed a marked increase of peak aortic flow velocity as compared with the immediate post-valvoplasty value. The patient

  15. Keeping Current. African American History Month--More than Book Reports!

    Science.gov (United States)

    O'Neal, Anita J.

    2005-01-01

    Mention the observance of African American History Month and the name Carter G. Woodson immediately comes to mind. Woodson, an educator, publisher, and historian, initiated the "Negro History Week" observance in 1926. Known as the "Father of Black History," Woodson believed that it was important for African Americans to know their history in…

  16. High multiple paternity and low last-male sperm precedence in a hermaphroditic planarian flatworm: consequences for reciprocity patterns.

    Science.gov (United States)

    Pongratz, N; Michiels, N K

    2003-06-01

    It is difficult to predict a priori how mating success translates into fertilization success in simultaneous hermaphrodites with internal fertilization. Whereas insemination decisions will be determined by male interests, fertilization will depend on female interests, possibly leading to discrepancies between insemination and fertilization patterns. The planarian flatworm Schmidtea polychroa, a simultaneous hermaphrodite in which mating partners trade sperm was studied. Sperm can be stored for months yet individuals mate frequently. Using microsatellites, maternity and paternity data were obtained from 748 offspring produced in six groups of 10 individuals during four weeks. Adults produced young from four mates on average. Reciprocal fertilization between two mates was found in only 41 out of 110 registered mate combinations, which is clearly less than what is predicted from insemination patterns. Multiple paternity was high: > 80% of all cocoons had two to five fathers for only three to five offspring per cocoon. Because animals were collected from a natural population, 28% of all hatchlings were sired by unknown sperm donors in the field, despite a 10-day period of acclimatization and within-group mating. This percentage decreased only moderately throughout the experiment, showing that sperm can be stored and used for at least a month, despite frequent mating and sperm digestion. The immediate paternity a sperm donor could expect to obtain was only about 25%. Male reproductive success increased linearly with the number of female partners, providing support for Bateman's principle in hermaphrodites. Our results suggest that hermaphrodites do not trade fertilizations when trading sperm during insemination, lending support to the view that such conditional sperm exchange is driven by exchange of resources.

  17. Axonal outgrowth is associated with increased ERK 1/2 activation but decreased caspase 3 linked cell death in Schwann cells after immediate nerve repair in rats

    Directory of Open Access Journals (Sweden)

    Kanje Martin

    2011-01-01

    Full Text Available Abstract Background Extracellular-signal regulated kinase (ERK1/2 is activated by nerve damage and its activation precedes survival and proliferation of Schwann cells. In contrast, activation of caspase 3, a cysteine protease, is considered as a marker for apoptosis in Schwann cells. In the present study, axonal outgrowth, activation of ERK1/2 by phosphorylation (p-ERK 1/2 and immunoreactivity of cleaved caspase 3 were examined after immediate, delayed, or no repair of transected rat sciatic nerves. Results Axonal outgrowth, detected by neurofilament staining, was longer after immediate repair than after either the delayed or no repair conditions. Immediate repair also showed a higher expression of p-ERK 1/2 and a lower number of cleaved caspase 3 stained Schwann cells than after delayed nerve repair. If the transected nerve was not repaired a lower level of p-ERK 1/2 was found than in either the immediate or delayed repair conditions. Axonal outgrowth correlated to p-ERK 1/2, but not clearly with cleaved caspase 3. Contact with regenerating axons affected Schwann cells with respect to p-ERK 1/2 and cleaved caspase 3 after immediate nerve repair only. Conclusion The decreased regenerative capacity that has historically been observed after delayed nerve repair may be related to impaired activation of Schwann cells and increased Schwann cell death. Outgrowing axons influence ERK 1/2 activation and apoptosis of Schwann cells.

  18. Noble metal nanoclusters and nanoparticles precede mineral formation in magmatic sulphide melts.

    Science.gov (United States)

    Helmy, Hassan M; Ballhaus, Chris; Fonseca, Raúl O C; Wirth, Richard; Nagel, Thorsten; Tredoux, Marian

    2013-01-01

    In low temperature aqueous solutions, it has long been recognized by in situ experiments that many minerals are preceded by crystalline nanometre-sized particles and non-crystalline nanophases. For magmatic systems, nanometre-sized precursors have not yet been demonstrated to exist, although the suggestion has been around for some time. Here we demonstrate by high temperature quench experiments that platinum and arsenic self-organize to nanoparticles, well before the melt has reached a Pt-As concentration at which discrete Pt arsenide minerals become stable phases. If all highly siderophile elements associate to nanophases in undersaturated melts, the distribution of the noble metals between silicate, sulphide and metal melts will be controlled by the surface properties of nano-associations, more so than by the chemical properties of the elements.

  19. The checkpoint for agonist selection precedes conventional selection in human thymus.

    Science.gov (United States)

    Verstichel, Greet; Vermijlen, David; Martens, Liesbet; Goetgeluk, Glenn; Brouwer, Margreet; Thiault, Nicolas; Van Caeneghem, Yasmine; De Munter, Stijn; Weening, Karin; Bonte, Sarah; Leclercq, Georges; Taghon, Tom; Kerre, Tessa; Saeys, Yvan; Van Dorpe, Jo; Cheroutre, Hilde; Vandekerckhove, Bart

    2017-02-24

    The thymus plays a central role in self-tolerance, partly by eliminating precursors with a T cell receptor (TCR) that binds strongly to self-antigens. However, the generation of self-agonist-selected lineages also relies on strong TCR signaling. How thymocytes discriminate between these opposite outcomes remains elusive. Here, we identified a human agonist-selected PD-1(+) CD8αα(+) subset of mature CD8αβ(+) T cells that displays an effector phenotype associated with agonist selection. TCR stimulation of immature post-β-selection thymocyte blasts specifically gives rise to this innate subset and fixes early T cell receptor alpha variable (TRAV) and T cell receptor alpha joining (TRAJ) rearrangements in the TCR repertoire. These findings suggest that the checkpoint for agonist selection precedes conventional selection in the human thymus. Copyright © 2017, American Association for the Advancement of Science.

  20. The tailings dam failure of 5 November 2015 in SE Brazil and its preceding seismic sequence

    Science.gov (United States)

    Agurto-Detzel, H.; Bianchi, M.; Assumpção, M.; Schimmel, M.; Collaço, B.; Ciardelli, C.; Barbosa, J. R.; Calhau, J.

    2016-05-01

    The collapse of a mine tailings dam and subsequent flood in SE Brazil on 5 November 2015 was preceded by a small-magnitude seismic sequence. In this report, we explore the spatiotemporal associations between the seismic events and the accident and discuss their possible connection. We also analyze the signals generated by the turbulent mudflow, as recorded by the Brazilian Seismographic Network (RSBR). In light of our observations, we propose as possible contributing factor for the dam collapse either ground shaking and/or soil liquefaction triggered by the earthquakes. The possibility of such a small-magnitude earthquake contributing to the collapse of a tailings dam raises important concerns regarding safety and related legislation of dams in Brazil and the world.

  1. Enhancement of visual attention precedes the emergence of novel metaphor interpretations.

    Science.gov (United States)

    Terai, Asuka; Nakagawa, Masanori; Kusumi, Takashi; Koike, Yasuharu; Jimura, Koji

    2015-01-01

    Emergence of creative ideas often involves sudden linking of unrelated ideas. Here we demonstrate that the production of insights about novel metaphor was preceded by prolonged visual inspection of metaphorical sentences. The participants made free spoken responses in a task requiring the generation of semantic interpretations about visually presented sentences, where gaze locations were continuously monitored. We found that creative interpretations were primarily generated from novel metaphorical expressions, rather than from conventional expressions. Moreover, presented words within novel metaphors were visually inspected for longer periods specifically before creative interpretations were produced. Interestingly, prolonged gazes occurred several seconds (∼8 s) prior to the generation of creative interpretations, particularly, in the case of the topic word within the metaphor. These results demonstrate latent cognitive process meditating the emergence of insights, and suggest that the prior visual inspection prompted the semantic representation of the metaphorical sentences, which eventually facilitates creative ideas.

  2. Energy crisis precedes global metabolic failure in a novel Caenorhabditis elegans Alzheimer Disease model.

    Science.gov (United States)

    Fong, Sheng; Teo, Emelyne; Ng, Li Fang; Chen, Ce-Belle; Lakshmanan, Lakshmi Narayanan; Tsoi, Sau Yee; Moore, Philip Keith; Inoue, Takao; Halliwell, Barry; Gruber, Jan

    2016-09-22

    Alzheimer Disease (AD) is a progressive neurological disorder characterized by the deposition of amyloid beta (Aβ), predominantly the Aβ1-42 form, in the brain. Mitochondrial dysfunction and impaired energy metabolism are important components of AD pathogenesis. However, the causal and temporal relationships between them and AD pathology remain unclear. Using a novel C. elegans AD strain with constitutive neuronal Aβ1-42 expression that displays neuromuscular defects and age-dependent behavioural dysfunction reminiscent of AD, we have shown that mitochondrial bioenergetic deficit is an early event in AD pathogenesis, preceding dysfunction of mitochondrial electron transfer chain (ETC) complexes and the onset of global metabolic failure. These results are consistent with an emerging view that AD may be a metabolic neurodegenerative disease, and also confirm that Aβ-driven metabolic and mitochondrial effects can be reproduced in organisms separated by large evolutionary distances.

  3. Adaptive control for a class of nonlinear time-delay systems preceded by unknown hysteresis

    Science.gov (United States)

    Zhang, Xiuyu; Lin, Yan

    2013-08-01

    In this article, a robust adaptive neural dynamic surface control is proposed for a class of time-delay nonlinear systems preceded by saturated hystereses. Compared with the present schemes of dealing with time delay and hystereses input, the main advantages of the proposed scheme are that the prespecified transient and steady-state performance of tracking error can be guaranteed, the computational burden can be greatly reduced and the explosion of complexity problem inherent in backstepping control can be eliminated. Moreover, the utilisation of saturated-type Prandtl-Ishlinskii model makes our scheme more applicable. It is proved that the new scheme can guarantee all the closed-loop signals semiglobally uniformly ultimate bounded. Simulation results are presented to demonstrate the validity of the proposed scheme.

  4. a Revised Stochastic Optimal Velocity Model Considering the Velocity Gap with a Preceding Vehicle

    Science.gov (United States)

    Shigaki, Keizo; Tanimoto, Jun; Hagishima, Aya

    The stochastic optimal velocity (SOV) model, which is a cellular automata model, has been widely used because of its good reproducibility of the fundamental diagram, despite its simplicity. However, it has a drawback: in SOV, a vehicle that is temporarily stopped takes a long time to restart. This study proposes a revised SOV model that suppresses this particular defect; the basic concept of this model is derived from the car-following model, which considers the velocity gap between a particular vehicle and the preceding vehicle. A series of simulations identifies the model parameters and clarifies that the proposed model can reproduce the three traffic phases: free, jam, and even synchronized phases, which cannot be achieved by the conventional SOV model.

  5. Terrorist attacks escalate in frequency and fatalities preceding highly lethal attacks.

    Science.gov (United States)

    Martens, Andy; Sainudiin, Raazesh; Sibley, Chris G; Schimel, Jeff; Webber, David

    2014-01-01

    Highly lethal terrorist attacks, which we define as those killing 21 or more people, account for 50% of the total number of people killed in all terrorist attacks combined, yet comprise only 3.5% of terrorist attacks. Given the disproportionate influence of these incidents, uncovering systematic patterns in attacks that precede and anticipate these highly lethal attacks may be of value for understanding attacks that exact a heavy toll on life. Here we examined whether the activity of terrorist groups escalates--both in the number of people killed per attack and in the frequency of attacks--leading up to highly lethal attacks. Analyses of terrorist attacks drawn from a state-of-the-art international terrorism database (The Global Terrorism Database) showed evidence for both types of escalation leading up to highly lethal attacks, though complexities to the patterns emerged as well. These patterns of escalation do not emerge among terrorist groups that never commit a highly lethal attack.

  6. An investigation into the precedents of modern drug treatment in psychiatry.

    Science.gov (United States)

    Moncrieff, J

    1999-12-01

    This paper examines some of the factors associated with the introduction of a range of new drug treatments into psychiatry in the 1950s and 1960s. The nature of psychiatry in the United Kingdom in preceding decades is examined and a continuous emphasis on biological explanations and treatments of mental disorder is revealed. Physical treatment procedures such as insulin coma therapy and shock treatment received most attention. Older drug treatments, although widely used, excited little interest during this time. The new drug treatments by contrast received much attention and began to be regarded as having specific effects on different mental disorders. It is suggested that a combination of long-standing professional concerns and commercial factors helped to account for the rapid acceptance and employment of the new drugs. In turn, these drugs helped to strenghten the hegemony of the medical approach to mental illness.

  7. Preceding bronchial cutting for exposure of the pulmonary artery buried in scar tissue after chemoradiotherapy.

    Science.gov (United States)

    Nomori, Hiroaki; Cong, Yue; Sugimura, Hiroshi

    2017-01-01

    It is often difficult to expose the pulmonary artery buried in a scar tissue, especially in lung cancer patients that responded well to neoadjuvant chemoradiotherapy. Difficulty to access pulmonary artery branches may lead to potentially unnecessary pneumonectomy. To complete lobectomy in such cases, a technique with preceding bronchial cutting for exposure of the pulmonary artery is presented. After dissecting the pulmonary vein, the lobar bronchus is cut from the opposite side of the pulmonary artery with scissors. The back wall of the lobar bronchus is cut using a surgical knife from the luminal face, which can expose the pulmonary artery behind the bronchial stump and then complete lobectomy. Fourteen patients have been treated using the present technique, enabling complete resection by lobectomy (including sleeve lobectomy in 3 patients) without major bleeding. The present procedure can expose pulmonary artery buried in scar tissue, resulting in making the lobectomy safer.

  8. Cerebral complexity preceded enlarged brain size and reduced olfactory bulbs in Old World monkeys.

    Science.gov (United States)

    Gonzales, Lauren A; Benefit, Brenda R; McCrossin, Monte L; Spoor, Fred

    2015-07-03

    Analysis of the only complete early cercopithecoid (Old World monkey) endocast currently known, that of 15-million-year (Myr)-old Victoriapithecus, reveals an unexpectedly small endocranial volume (ECV) relative to body size and a large olfactory bulb volume relative to ECV, similar to extant lemurs and Oligocene anthropoids. However, the Victoriapithecus brain has principal and arcuate sulci of the frontal lobe not seen in the stem catarrhine Aegyptopithecus, as well as a distinctive cercopithecoid pattern of gyrification, indicating that cerebral complexity preceded encephalization in cercopithecoids. Since larger ECVs, expanded frontal lobes, and reduced olfactory bulbs are already present in the 17- to 18-Myr-old ape Proconsul these features evolved independently in hominoids (apes) and cercopithecoids and much earlier in the former. Moreover, the order of encephalization and brain reorganization was apparently different in hominoids and cercopithecoids, showing that brain size and cerebral organization evolve independently.

  9. A Hybrid Genetic Algorithm to Minimize Total Tardiness for Unrelated Parallel Machine Scheduling with Precedence Constraints

    Directory of Open Access Journals (Sweden)

    Chunfeng Liu

    2013-01-01

    Full Text Available The paper presents a novel hybrid genetic algorithm (HGA for a deterministic scheduling problem where multiple jobs with arbitrary precedence constraints are processed on multiple unrelated parallel machines. The objective is to minimize total tardiness, since delays of the jobs may lead to punishment cost or cancellation of orders by the clients in many situations. A priority rule-based heuristic algorithm, which schedules a prior job on a prior machine according to the priority rule at each iteration, is suggested and embedded to the HGA for initial feasible schedules that can be improved in further stages. Computational experiments are conducted to show that the proposed HGA performs well with respect to accuracy and efficiency of solution for small-sized problems and gets better results than the conventional genetic algorithm within the same runtime for large-sized problems.

  10. Rapid genetic adaptation precedes the spread of an exotic plant species.

    Science.gov (United States)

    Vandepitte, Katrien; de Meyer, Tim; Helsen, Kenny; van Acker, Kasper; Roldán-Ruiz, Isabel; Mergeay, Joachim; Honnay, Olivier

    2014-05-01

    Human activities have increasingly introduced plant species far outside their native ranges under environmental conditions that can strongly differ from those originally met. Therefore, before spreading, and potentially causing ecological and economical damage, non-native species may rapidly evolve. Evidence of genetically based adaptation during the process of becoming invasive is very scant, however, which is due to the lack of knowledge regarding the historical genetic makeup of the introduced populations and the lack of genomic resources. Capitalizing on the availability of old non-native herbarium specimens, we examined frequency shifts in genic SNPs of the Pyrenean Rocket (Sisymbrium austriacum subsp. chrysanthum), comparing the (i) native, (ii) currently spreading non-native and (iii) historically introduced gene pool. Results show strong divergence in flowering time genes during the establishment phase, indicating that rapid genetic adaptation preceded the spread of this species and possibly assisted in overcoming environmental constraints.

  11. Apoptosis Mediated by HIV Protease is Preceded by Cleavage of Bcl-2

    Science.gov (United States)

    Strack, Peter R.; West Frey, Michelle; Rizzo, Christopher J.; Cordova, Beverly; George, Henry J.; Meade, Raymond; Ho, Siew Peng; Corman, Jeanne; Tritch, Radonna; Korant, Bruce D.

    1996-09-01

    Expression of the human immunodeficiency virus type 1 (HIV) protease in cultured cells leads to apoptosis, preceded by cleavage of bcl-2, a key negative regulator of cell death. In contrast, a high level of bcl-2 protects cells in vitro and in vivo from the viral protease and prevents cell death following HIV infection of human lymphocytes, while reducing the yields of viral structural proteins, infectivity, and tumor necrosis factor α . We present a model for HIV replication in which the viral protease depletes the infected cells of bcl-2, leading to oxidative stress-dependent activation of NFkappa B, a cellular factor required for HIV transcription, and ultimately to cell death. Purified bcl-2 is cleaved by HIV protease between phenylalanine 112 and alanine 113. The results suggest a new option for HIV gene therapy; bcl-2 muteins that have noncleavable alterations surrounding the HIV protease cleavage site.

  12. Effects of semantic relatedness on recall of stimuli preceding emotional oddballs.

    Science.gov (United States)

    Smith, Ryan M; Beversdorf, David Q

    2008-07-01

    Semantic and episodic memory networks function as highly interconnected systems, both relying on the hippocampal/medial temporal lobe complex (HC/MTL). Episodic memory encoding triggers the retrieval of semantic information, serving to incorporate contextual relationships between the newly acquired memory and existing semantic representations. While emotional material augments episodic memory encoding at the time of stimulus presentation, interactions between emotion and semantic memory that contribute to subsequent episodic recall are not well understood. Using a modified oddball task, we examined the modulatory effects of negative emotion on semantic interactions with episodic memory by measuring the free-recall of serially presented neutral or negative words varying in semantic relatedness. We found increased free-recall for words related to and preceding emotionally negative oddballs, suggesting that negative emotion can indirectly facilitate episodic free-recall by enhancing semantic contributions during encoding. Our findings demonstrate the ability of emotion and semantic memory to interact to mutually enhance free-recall.

  13. The chemistry that preceded life's origin: a study guide from meteorites.

    Science.gov (United States)

    Pizzarello, Sandra

    2007-04-01

    Carbonaceous meteorites are rare fragments of asteroids that contain organic carbon of diverse composition, various complexity, and whose lineage can in several instances be traced back to pre-solar environments. Their analyses offer a unique glimpse into the chemistry of the solar system that preceded life and may have been available to its emergence on the early Earth. While the heterogeneity of the organic materials of meteorites is indicative of random synthetic processes for their formation, some of their components have identical counterparts in the biosphere, and a group of meteoritic amino acids were found to display chiral asymmetry, a property known since the time of Pasteur to be inextricably linked to life's processes. The ability of these amino acids to act as asymmetric catalysts, as well as indications that molecular asymmetry in meteorites may not be limited to these compounds, encourage the suggestion of possible involvement of meteoritic material in the induction of selective traits in molecular evolution.

  14. Enhancement of visual attention precedes the emergence of novel metaphor interpretations

    Science.gov (United States)

    Terai, Asuka; Nakagawa, Masanori; Kusumi, Takashi; Koike, Yasuharu; Jimura, Koji

    2015-01-01

    Emergence of creative ideas often involves sudden linking of unrelated ideas. Here we demonstrate that the production of insights about novel metaphor was preceded by prolonged visual inspection of metaphorical sentences. The participants made free spoken responses in a task requiring the generation of semantic interpretations about visually presented sentences, where gaze locations were continuously monitored. We found that creative interpretations were primarily generated from novel metaphorical expressions, rather than from conventional expressions. Moreover, presented words within novel metaphors were visually inspected for longer periods specifically before creative interpretations were produced. Interestingly, prolonged gazes occurred several seconds (∼8 s) prior to the generation of creative interpretations, particularly, in the case of the topic word within the metaphor. These results demonstrate latent cognitive process meditating the emergence of insights, and suggest that the prior visual inspection prompted the semantic representation of the metaphorical sentences, which eventually facilitates creative ideas. PMID:26167155

  15. Improved heuristic algorithm for selection of tear streams and precedence ordering in process flowsheeting computations

    Directory of Open Access Journals (Sweden)

    Kristian M. Lien

    1990-01-01

    Full Text Available This paper presents a new algorithm based on the heuristic tearing algorithm by Gundersen and Hertzberg (1983. The basic idea in both the original and the proposed algorithm is sequential tearing of strong components which have been identified by an algorithm proposed by Targan (1972. The new algorithm has two alternative options for selection of tear streams, and alternative precedence orderings may be generated for the selected set of tear streams. The algorithm has been tested on several problems. It has identified minimal (optimal tear sets for all of them, including the four problems presented in Gundersen and Hertzberg (1983 where the original algorithm could not find a minimal tear set. A Lisp implementation of the algorithm is described, and example problems arc presented.

  16. Energy crisis precedes global metabolic failure in a novel Caenorhabditis elegans Alzheimer Disease model

    Science.gov (United States)

    Fong, Sheng; Teo, Emelyne; Ng, Li Fang; Chen, Ce-Belle; Lakshmanan, Lakshmi Narayanan; Tsoi, Sau Yee; Moore, Philip Keith; Inoue, Takao; Halliwell, Barry; Gruber, Jan

    2016-01-01

    Alzheimer Disease (AD) is a progressive neurological disorder characterized by the deposition of amyloid beta (Aβ), predominantly the Aβ1–42 form, in the brain. Mitochondrial dysfunction and impaired energy metabolism are important components of AD pathogenesis. However, the causal and temporal relationships between them and AD pathology remain unclear. Using a novel C. elegans AD strain with constitutive neuronal Aβ1–42 expression that displays neuromuscular defects and age-dependent behavioural dysfunction reminiscent of AD, we have shown that mitochondrial bioenergetic deficit is an early event in AD pathogenesis, preceding dysfunction of mitochondrial electron transfer chain (ETC) complexes and the onset of global metabolic failure. These results are consistent with an emerging view that AD may be a metabolic neurodegenerative disease, and also confirm that Aβ-driven metabolic and mitochondrial effects can be reproduced in organisms separated by large evolutionary distances. PMID:27653553

  17. Best pictures of the month

    CERN Multimedia

    Claudia Marcelloni de Oliveira

    The last sector of the Big Muon Wheels was brought to the cavern in the morning of September 20... ... installed on one of the Big Muon Wheels during the same afternoon... ... just in time to sqeeze lots of people in between two of the all-completed Big Muon Wheels on the 21st of September to celebrate the installation of the last sector. Installation of the first ATLAS small wheel in building 191 on September 10. Some of the people involved in the construction and installation of the chambers on the first ATLAS small wheel in building 191 celebrating its completion on September 20. After hearing that the rock band The Police played in Geneva last month, Muriel got inspired and decided to become a rock star, just like one of her favorites, Keith Richards from the Rolling Stones. Special accomplishment of the month: (top) Martina Hurwitz (#908) and Monica Dunford (680), both from the Chicago University group, completed the Lausanne Marathon on October 21 in 4h 4...

  18. Petroleum supply monthly, April 1990

    Energy Technology Data Exchange (ETDEWEB)

    None

    1990-06-26

    The Petroleum Supply Monthly (PSM) is one of a family of three publications produced by the Petroleum Supply Division within the Energy Information Administration (EIA) reflecting different levels of data timeliness and completeness. The other two publications are the Weekly Petroleum Status Report (WPSR) and the Petroleum Supply Annual (PSA). Data presented in the Petroleum Supply Monthly describe (PSM) the supply and disposition of petroleum products in the United States and major US geographic regions. The data series describe production, imports and exports, inter-Petroleum Administration for Defense (PAD) District movements, and inventories by the primary suppliers of petroleum products in the United States (50 States and the District of Columbia). The reporting universe includes those petroleum sectors in Primary Supply.'' Included are: petroleum refiners, motor gasoline blenders, operators of natural gas processing plants and fractionators, inter-PAD transporters, importers, and major inventory holders of petroleum products and crude oil. When aggregated, the data reported by these sectors approximately represent the consumption of petroleum products in the United States. Data presented in the PSM are divided into two sections: (1) the Summary Statistics and (2) the Detailed Statistics.

  19. Natural gas monthly, February 1998

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1998-02-01

    This issue of the Natural Gas Monthly (NGM) presents the most recent estimates of natural gas data from the Energy Information Administration. Estimates extend through February 1998 for many data series, and through November 1997 for most natural gas prices. Highlights of the natural gas data contained in this issue are: Preliminary estimates for January and February 1998 show that dry natural gas production, net imports, and consumption are all within 1 percent of their levels in 1997. Warmer-than-normal weather in recent months has resulted in lower consumption of natural gas by the residential sector and lower net withdrawals of gas from under round storage facilities compared with a year ago. This has resulted in an estimate of the amount of working gas in storage at the end of February 1998 that is 18 percent higher than in February 1997. The national average natural gas wellhead price is estimated to be $3.05 per thousand cubic feet in November 1997, 7 percent higher than in October. The cumulative average wellhead price for January through November 1997 is estimated to be $2.42 per thousand cubic feet, 17 percent above that of the same period in 1996. This price increase is far less than 36-percent rise that occurred between 1995 and 1996. 6 figs., 26 tabs.

  20. Alteration of antioxidant defense status precedes humoral immune response abnormalities in macrosomia

    Science.gov (United States)

    Haddouche, Mustapha; Aribi, Mourad; Moulessehoul, Soraya; Smahi, Mohammed Chems-Eddine Ismet; Lammani, Mohammed; Benyoucef, Mohammed

    2011-01-01

    Summary Background This study aimed to investigate whether the anomalies affecting the antioxidant and humoral immune defenses could start at birth and to check whether the decrease in antioxidant defenses may precede the immune abnormalities in macrosomic newborns. Material/Methods Thirty macrosomic and 30 sex-matched control newborns were recruited for a retrospective case-control study at the Maghnia Maternity Hospital of Tlemcen Department (Algeria). Results The serum IgG levels were similar in both groups. However, plasma ORAC, albumin, vitamin E, SOD, CAT and GSH-Px levels were significantly decreased in macrosomic as compared to control newborns, yet no difference was observed after adjustment for weight. Additionally, serum concentrations of complement C3, MDA and XO were significantly higher in macrosomic as compared to controls before adjustment for weight. Moreover, macrosomia was significantly associated with high levels of complement C3 (OR=8, p=0.002); whereas no association with those of IgG was observed (OR0.05). Furthermore, macrosomia was significantly associated with low levels of ORAC (OR=4.96, p=0.027), vitamin E (OR=4.5, p=0.018), SOD (OR=6.88, p=0.020) and CAT (OR=5.67, p=0.017), and with high levels of MDA (OR=10.29, p=0.005). Conclusions Abnormalities of the humoral defense system in excessive weight could be preceded by alterations of the anti-oxidative defense and by inflammatory response and activation of innate immunity at birth. Additionally, excessive weight could be a potential factor contributing to decreased anti-oxidative capacity and increased oxidative stress. PMID:22037745

  1. Behaviour patterns preceding a railway suicide: explorative study of German Federal Police officers' experiences.

    Science.gov (United States)

    Lukaschek, Karoline; Baumert, Jens; Ladwig, Karl-Heinz

    2011-08-04

    Constant high-level numbers of railway suicides indicate that prevention strategies against railway suicides are urgently needed. The main question of the present study was whether pre-crash railway suicide behaviour can be identified, using German Federal Police officers experience with suicidal events in railway related environments. To collect information on pre-crash railway suicide behaviour, a questionnaire was used and made available on the German Federal Police intranet. A total of 202 subjects (mean age: 41 years, sex: 84.9% male) were included in the analysis. Multivariate logistic regression analyses were performed to predict the prevention of suicide (first model) or demand for counselling (second model) as outcomes. Sex, age, years of service, number of experienced suicides, suicides personally observed, information on suicides obtained from witnesses and finally either counselling/debriefing (first model) or whether officers had prevented a suicide (second model) were used as predictors. A considerable proportion of police officers reported behavioural patterns preceding a suicide. Half of them observed the dropping or leaving behind of personal belongings or the avoidance of eye contact, more than a third erratic gesture, mimic or movement. Erratic communication patterns and general confusion were each reported by about one quarter. One fifth indicated the influence of alcohol. Less frequently observed behaviour was aimlessly wandering (14.3%) and out of the ordinary clothing (4%). About one third of all railway suicide victims committed suicide in stations. Of those, 70% had chosen an eminent spot. The multivariate logistic regression model using prevented suicides as the outcome identified the number of suicides experienced, counselling/debriefing and having personally observed a suicide as variables with significant impact. The model using counselling/debriefing as the outcome identified age and having prevented a suicide as variables with a

  2. Prolonged hyperpolarizing potentials precede spindle oscillations in the thalamic reticular nucleus

    Science.gov (United States)

    Fuentealba, Pablo; Timofeev, Igor; Steriade, Mircea

    2004-01-01

    The thalamic reticular (RE) nucleus is a key structure in the generation of spindles, a hallmark bioelectrical oscillation during early stages of sleep. Intracellular recordings of RE neurons in vivo revealed the presence of prolonged hyperpolarizing potentials preceding spindles in a subgroup (30%) of neurons. These hyperpolarizations (6-10 mV) lasted for 200-300 ms and were present just before the onset of spontaneously occurring spindle waves. Corticothalamic volleys also were effective in generating such hyperpolarizations followed by spindles in RE neurons. A drop of up to 40% in the apparent input resistance (Rin) was associated with these hyperpolarizing potentials, suggesting an active process rather than disfacilitation. Accordingly, the reversal potential was approximately -100 mV for both spontaneous and cortically elicited hyperpolarizations, consistent with the activation of slow K+ conductances. QX-314 in the recording pipettes decreased both the amplitude and incidence of prolonged hyperpolarizations, suggesting the participation of G protein-dependent K+ currents in the generation of hyperpolarizations. Simultaneous extracellular and intracellular recordings in the RE nucleus demonstrated that some RE neurons discharged during the hyperpolarizations and, thus, may be implicated in their generation. The prolonged hyperpolarizations preceding spindles may play a role in the transition from tonic to bursting firing of RE neurons within a range of membrane potential (-60 to -65 mV) at which they set favorable conditions for the generation of low-threshold spike bursts that initiate spindle sequences. These data are further arguments for the generation of spindles within the thalamic RE nucleus. PMID:15210981

  3. Alteration of antioxidant defense status precedes humoral immune response abnormalities in macrosomia.

    Science.gov (United States)

    Haddouche, Mustapha; Aribi, Mourad; Moulessehoul, Soraya; Smahi, Mohammed Chems-Eddine Ismet; Lammani, Mohammed; Benyoucef, Mohammed

    2011-11-01

    This study aimed to investigate whether the anomalies affecting the antioxidant and humoral immune defenses could start at birth and to check whether the decrease in antioxidant defenses may precede the immune abnormalities in macrosomic newborns. Thirty macrosomic and 30 sex-matched control newborns were recruited for a retrospective case-control study at the Maghnia Maternity Hospital of Tlemcen Department (Algeria). The serum IgG levels were similar in both groups. However, plasma ORAC, albumin, vitamin E, SOD, CAT and GSH-Px levels were significantly decreased in macrosomic as compared to control newborns, yet no difference was observed after adjustment for weight. Additionally, serum concentrations of complement C3, MDA and XO were significantly higher in macrosomic as compared to controls before adjustment for weight. Moreover, macrosomia was significantly associated with high levels of complement C3 (OR=8, p=0.002); whereas no association with those of IgG was observed (OR0.05). Furthermore, macrosomia was significantly associated with low levels of ORAC (OR=4.96, p=0.027), vitamin E (OR=4.5, p=0.018), SOD (OR=6.88, p=0.020) and CAT (OR=5.67, p=0.017), and with high levels of MDA (OR=10.29, p=0.005). Abnormalities of the humoral defense system in excessive weight could be preceded by alterations of the anti-oxidative defense and by inflammatory response and activation of innate immunity at birth. Additionally, excessive weight could be a potential factor contributing to decreased anti-oxidative capacity and increased oxidative stress.

  4. The Stress and Vascular Catastrophes in Newborn Rats: Mechanisms Preceding and Accompanying the Brain Hemorrhages

    Science.gov (United States)

    Semyachkina-Glushkovskaya, Oxana; Borisova, Ekaterina; Abakumov, Maxim; Gorin, Dmitry; Avramov, Latchezar; Fedosov, Ivan; Namykin, Anton; Abdurashitov, Arkady; Serov, Alexander; Pavlov, Alexey; Zinchenko, Ekaterina; Lychagov, Vlad; Navolokin, Nikita; Shirokov, Alexander; Maslyakova, Galina; Zhu, Dan; Luo, Qingming; Chekhonin, Vladimir; Tuchin, Valery; Kurths, Jürgen

    2016-01-01

    In this study, we analyzed the time-depended scenario of stress response cascade preceding and accompanying brain hemorrhages in newborn rats using an interdisciplinary approach based on: a morphological analysis of brain tissues, coherent-domain optical technologies for visualization of the cerebral blood flow, monitoring of the cerebral oxygenation and the deformability of red blood cells (RBCs). Using a model of stress-induced brain hemorrhages (sound stress, 120 dB, 370 Hz), we studied changes in neonatal brain 2, 4, 6, 8 h after stress (the pre-hemorrhage, latent period) and 24 h after stress (the post-hemorrhage period). We found that latent period of brain hemorrhages is accompanied by gradual pathological changes in systemic, metabolic, and cellular levels of stress. The incidence of brain hemorrhages is characterized by a progression of these changes and the irreversible cell death in the brain areas involved in higher mental functions. These processes are realized via a time-depended reduction of cerebral venous blood flow and oxygenation that was accompanied by an increase in RBCs deformability. The significant depletion of the molecular layer of the prefrontal cortex and the pyramidal neurons, which are crucial for associative learning and attention, is developed as a consequence of homeostasis imbalance. Thus, stress-induced processes preceding and accompanying brain hemorrhages in neonatal period contribute to serious injuries of the brain blood circulation, cerebral metabolic activity and structural elements of cognitive function. These results are an informative platform for further studies of mechanisms underlying stress-induced brain hemorrhages during the first days of life that will improve the future generation's health. PMID:27378933

  5. An increased risk of urinary tract infection precedes development of primary biliary cirrhosis

    Directory of Open Access Journals (Sweden)

    West Joe

    2011-08-01

    Full Text Available Abstract Background Primary Biliary Cirrhosis is known to be associated with Urinary Tract Infections (UTIs, but whether these precede or follow the liver disease is unclear. We have therefore attempted to determine whether UTIs are more common in people with Primary Biliary Cirrhosis (PBC prior to their diagnosis. Methods We conducted a case control study in the General Practice Research Database. All cases of PBC first recorded at least one year after entry to the dataset were selected along with up to 10 controls matched for age, sex. A second unmatched control group who had Chronic Liver Diseases but not PBC were chosen. The main exposures studied were the occurrence of Urinary tract infections and pyelonephritis at least one or at least five years before diagnosis. We also performed an analysis restricted to those younger than 55 at diagnosis, as we hypothesized the relationship to be stronger in the younger age group. Results PBC is associated with UTI prior to diagnosis, OR 1.50 (CI 1.26-1.78, which was similar 5 years prior to diagnosis and after adjusting for smoking. The strongest relationships were observed in pyelonephritis exposures five years before diagnosis in cases under 55 years: adjusted odds ratios were 2.60 (1.02-6.63 in comparison with matched general population controls and adjusted odds ratios were OR 2.45 (1.02-5.59 in the comparison with chronic liver disease controls. Conclusions We found that the association between urosepsis and PBC is specific to this disease and precedes the diagnosis of PBC in a manner not previously observed in human data. This is consistent with a causal relationship.

  6. Gene expression and metabolism preceding soft scald, a chilling injury of 'Honeycrisp' apple fruit.

    Science.gov (United States)

    Leisso, Rachel S; Gapper, Nigel E; Mattheis, James P; Sullivan, Nathanael L; Watkins, Christopher B; Giovannoni, James J; Schaffer, Robert J; Johnston, Jason W; Hanrahan, Ines; Hertog, Maarten L A T M; Nicolaï, Bart M; Rudell, David R

    2016-10-12

    'Honeycrisp' is an apple cultivar that is susceptible to soft scald, a chilling injury expressed as necrotic patches on the peel. Improved understanding of metabolism associated with the disorder would improve our understanding of soft scald and contribute to developing more effective management strategies for apple storage. It was expected that specific gene expression and specific metabolite levels in the peel would be linked with soft scald risk at harvest and/or specific time points during cold storage. Fruit from nine 'Honeycrisp' apple orchards that would eventually develop different incidences of soft scald between 4 and 8 weeks of cold air storage were used to contrast and determine differential transcriptomic and metabolomic changes during storage. Untargeted metabolic profiling revealed changes in a number of distinct pathways preceding and concurrent with soft scald symptom development, including elevated γ-aminobutryic acid (GABA), 1-hexanol, acylated steryl glycosides, and free p-coumaryl acyl esters. At harvest, levels of sesquiterpenoid and triterpenoid acyl esters were relatively higher in peel of fruit that did not later develop the disorder. RNA-seq driven gene expression profiling highlighted possible involvement of genes and associated metabolic processes with soft scald development. These included elevated expression of genes involved in lipid peroxidation and phenolic metabolism in fruit with soft scald, and isoprenoid/brassinosteroid metabolism in fruit that did not develop soft scald. Expression of other stress-related genes in fruit that developed soft scald included chlorophyll catabolism, cell wall loosening, and lipid transport while superoxide dismutases were up-regulated in fruit that did not develop the disorder. This study delineates the sequential transcriptomic and metabolomic changes preceding soft scald symptom development. Changes were differential depending on susceptibility of fruit to the disorder and could be attributed to

  7. Use of echosonography to monitor uterine placement of intrauterine devices after immediate postpartum insertions.

    Science.gov (United States)

    Ortiz Mariscal, J D; Guerrero Barrera, C; Wheeler, R G; Waszak, C S

    1987-02-01

    A study designed to monitor uterine placement of IUDs inserted immediately postpartum using echosonography was conducted at the Hospital de Gineco Obstetricia No. 23, "Dr. Ignacio Morones Prieto" in Monterrey, Mexico. TCu220 and Delta T IUDs were randomly assigned to, and inserted in women immediately following a normal vaginal delivery. Ultrasound examinations were to be performed within 60 min postinsertion, at 24 h postinsertion and at 1- and 3-month follow-up visits. There were no differences in the expulsion rates of the two device groups. Data are presented on the readings taken at the ultrasound examinations of the distance between the fundus and the upper part of the stem of the T. These differences differed significantly between the two device groups at the first ultrasound reading only (P less than or equal to 0.01). No relationship was found between the incidence of expulsion and the distance between the IUD and the fundus at any of the readings.

  8. Immediate provisional restoration of a single-tooth implant in the esthetic zone: A case report

    Directory of Open Access Journals (Sweden)

    Po-Sung Fu

    2011-02-01

    Full Text Available Immediate implant restoration of single implants may demonstrate a positive effect on peri-implant soft tissue. Placement of a provisional restoration following implant surgery can create soft tissue contours that resemble normal gingival topography before placement of the definitive prosthesis. This article describes a staged approach of the mandibular permanent right central incisor, which was congenital missing. The proper space for restoration of the missing incisor was created through orthodontic treatment. The scheduled implant site was reconstructed using autogenous bone harvested from the chin region. After a healing period of four months, an implant was installed with the connection of a fixed provisional crown to a prefabricated temporary abutment. The soft tissue around the implant healed according to the contours of the provisional restoration and the emergence profile was used to duplicate the definitive restoration. Peri-implant esthetics was achieved through the staged approach and immediate restoration of the implant.

  9. Immediate transient thrombocytopenia at the time of alemtuzumab infusion in multiple sclerosis.

    Science.gov (United States)

    Ranganathan, Usha; Kaunzner, Ulrike; Foster, Stacyann; Vartanian, Timothy; Perumal, Jai S

    2017-03-01

    Alemtuzumab is a monoclonal antibody approved for relapsing-remitting multiple sclerosis (RRMS). Although Immune thrombocytopenia (ITP) has been reported as a secondary autoimmune phenomenon following alemtuzumab infusion, immediate thrombocytopenia during the infusion has not been reported. We report transient, reversible, self-limiting acute-onset thrombocytopenia during the first course with alemtuzumab. In total, 3 of 22 paitents developed mild self-limited bruising associated with a drop in platelet count from their baseline during the intial 5-day course of alemtuzumab. Upon chart review, all 22 patients who received alemtuzumab developed an immediate mostly asymptomatic drop in platelet count which returned to normal within 2 months post-infusion.

  10. Use of transitional implants for immediate loading in mandibular complete dentures- A case report

    Directory of Open Access Journals (Sweden)

    Seema Bhoosreddy

    2009-01-01

    Full Text Available After the placement of implants in areas in which several teeth have been lost, both the clinician and the patient face many difficulties, particularly during healing. If no prosthesis is provided, the patient′s quality of life suffers. If a removable prosthesis is provided for optimum mastication and speech, many complicated adjustments of the denture may become necessary during healing, and the possibility of osseointegration failure increases. It has been reported that for implants to become osseointegrated, they must heal in the absence of functional loads for 4 to 6 months. To address the need for undisturbed healing and patient demand for uninterrupted immediate function and esthetics, the transitional implant system has been developed. This case report describes the use of transitional implants to support a removable mandibular overdenture. The transitional implant system is a sound and economical method of immediate patient restoration that allows for the protected healing of submerged implants.

  11. Human Cytomegalovirus Immediate Early Interaction with Host Nuclear Structures: Definition of an Immediate Transcript Environment

    Science.gov (United States)

    Ishov, Alexander M.; Stenberg, Richard M.; Maul, Gerd G.

    1997-01-01

    The development of an induced transcript environment was investigated at the supramolecular level through comparative localization of the human cytomegalovirus immediate early (IE) transcripts and specific nuclear domains shortly after infection. Compact aggregates of IE transcripts form only adjacent to nuclear domain 10 (ND10), and the viral protein IE86 accumulates exclusively juxtaposed to the subpopulation of ND10 with transcripts. The stream of transcripts is funneled from ND10 into the spliceosome assembly factor SC35 domain through the accumulation of IE86 protein, which recruits some components of the basal transcription machinery. Concomitantly the IE72 protein binds to ND10 and later disperses them. The domain containing the zinc finger region of IE72 is essential for this dispersal. Positional analysis of proteins IE86 and IE72, IE transcripts, ND10, the spliceosome assembly factor SC35, and basal transcription factors defines spatially and temporally an immediate transcript environment, the basic components of which exist in the cell before viral infection, providing the structural environment for the virus to usurp. PMID:9214377

  12. Immediate Postoperative Oral Nutrition Following Esophagectomy : A Multicenter Clinical Trial

    NARCIS (Netherlands)

    Weijs, Teus J.; Berkelmans, Gijs H. K.; Nieuwenhuijzen, Grard A. P.; Dolmans, Annemarie C. P.; Kouwenhoven, Ewout A.; Rosman, Camiel; Ruurda, Jelle P.; van Workum, Frans; van Det, J.; Silva Corten, Luis C.; van Hillegersberg, Richard; Luyer, Misha D. P.

    2016-01-01

    Background Immediate start of oral intake is beneficial following colorectal surgery. However, following esophagectomy the safety and feasibility of immediate oral intake is unclear, thus these patients are still kept nil by mouth. This study therefore aimed to determine the feasibility and safety o

  13. [Immediate cooling with water: emergency treatment of burns].

    Science.gov (United States)

    Latarjet, J

    1990-01-01

    Experimental data have demonstrated that prolonged immediate cooling with cold water is the best first-aid treatment for burn injuries. However in France, this treatment is rarely applied; instead old, inefficient and aggravating methods are still very popular. Pediatricians must help to change this practice by recommending immediate cold water treatment for burns in children.

  14. Monthly Narrative: Canaan National Wildlife Refuge 2007

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — This monthly narrative report for Canaan Valley National Wildlife Refuge outlines Refuge accomplishments month by month in 2007 from January through July. The report...

  15. Immediate Direct-To-Implant Breast Reconstruction Using Anatomical Implants

    Directory of Open Access Journals (Sweden)

    Sung-Eun Kim

    2014-09-01

    Full Text Available BackgroundIn 2012, a new anatomic breast implant of form-stable silicone gel was introduced onto the Korean market. The intended use of this implant is in the area of aesthetic breast surgery, and many reports are promising. Thus far, however, there have been no reports on the use of this implant for breast reconstruction in Korea. We used this breast implant in breast reconstruction surgery and report our early experience.MethodsFrom November 2012 to April 2013, the Natrelle Style 410 form-stable anatomically shaped cohesive silicone gel-filled breast implant was used in 31 breasts of 30 patients for implant breast reconstruction with an acellular dermal matrix. Patients were treated with skin-sparing mastectomies followed by immediate breast reconstruction.ResultsThe mean breast resection volume was 240 mL (range, 83-540 mL. The mean size of the breast implants was 217 mL (range, 125-395 mL. Breast shape outcomes were considered acceptable. Infection and skin thinning occurred in one patient each, and hematoma and seroma did not occur. Three cases of wound dehiscence occurred, one requiring surgical intervention, while the others healed with conservative treatment in one month. Rippling did not occur. So far, complications such as capsular contracture and malrotation of breast implant have not yet arisen.ConclusionsBy using anatomic breast implants in breast reconstruction, we achieved satisfactory results with aesthetics better than those obtained with round breast implants. Therefore, we concluded that the anatomical implant is suitable for breast reconstruction.

  16. Immediate loading with fixed full-arch prostheses in the maxilla: review of the literature.

    Science.gov (United States)

    Peñarrocha-Oltra, David; Covani, Ugo; Peñarrocha-Diago, Miguel; Peñarrocha-Diago, Maria

    2014-09-01

    To critically review the evidence-based literature on immediate loading of implants with fixed full-arch prostheses in the maxilla to determine 1) currently recommended performance criteria and 2) the outcomes that can be expected with this procedure. Studies from 2001 to 2011 on immediate loading with fixed full-arch maxillary prostheses were reviewed. Clinical series with at least 5 patients and 12 months of follow-up were included. Case reports, studies with missing data and repeatedly published studies were excluded. In each study the following was assessed: type of study, implant type, number of patients, number of implants, number of implants per patient, use of post-extraction implants, minimum implant length and diameter, type of prosthesis, time until loading, implant survival rate, prosthesis survival rate, marginal bone loss, complications and mean follow-up time. Criteria for patient selection, implant primary stability and bone regeneration were also studied. Thirteen studies were included, reporting a total of 2484 immediately loaded implants in 365 patients. Currently accepted performance criteria regarding patient and implant selection, and surgical and prosthetic procedures were deduced from the reviewed articles. Implant survival rates went from 87.5% to 100%, prosthesis survival rates from 93.8% to 100% and radiographic marginal bone loss from 0.8 mm to 1.6 mm.No intraoperative complications and only minor prosthetic complications were reported. The literature on immediate loading with fixed full-arch prostheses in the maxilla shows that a successful outcome can be expected if adequate criteria are used to evaluate the patient, choose the implant and perform the surgical and prosthetic treatment. Lack of homogeneity within studies limits the relevance of the conclusions that can be drawn, and more controlled randomized studies are necessary to enable comparison between the immediate and the conventional loading procedures.

  17. Petroleum supply monthly, July 1993

    Energy Technology Data Exchange (ETDEWEB)

    1993-07-29

    Data presented in the Petroleum Supply Monthly (PSM) describe the supply and disposition of petroleum products in the United States and major US geographic regions. The data series describe production, imports and exports, inter-Petroleum Administration for Defense (PAD) District movements, and inventories by the primary suppliers of petroleum products in the United States (50 States and the District of Columbia). The reporting universe includes those petroleum sectors in primary supply. Included are: Petroleum refiners, motor gasoline blenders, operators of natural gas processing plants and fractionators, inter-PAD transporters, importers, and major inventory holders of petroleum products and crude oil. When aggregated, the data reported by these sectors approximately represent the consumption of petroleum products in the United States.

  18. Petroleum supply monthly, August 1993

    Energy Technology Data Exchange (ETDEWEB)

    1993-09-01

    This publication the Petroleum Supply Monthly (PSM) is one of a family of four publications produced by the Petroleum Supply Division within the Energy Information Administration (EIA) reflecting different levels of data timeliness and completeness. The other publications are the Weekly Petroleum Status Report, (WPSR), the Winter Fuels Report, and the Petroleum Supply Annual (PSA). Data presented describe the supply and disposition of petroleum products in the United States and major US geographic regions. The data series describe production, imports and exports, inter-Petroleum Administration for Defense (PAD) District movements, and inventories by the primary suppliers of petroleum products in the United States (50 States and the District of Columbia). The reporting universe includes those petroleum sectors in primary supply. Included are: petroleum refiners, motor gasoline blenders, operators of natural gas processing plants and fractionators, inter-PAD transporters, importers, and major inventory holders of petroleum products and crude oil. Data presented are divided into Summary Statistics and Detailed Statistics.

  19. Petroleum supply monthly, August 1994

    Energy Technology Data Exchange (ETDEWEB)

    1994-08-26

    Data presented in the Petroleum Supply Monthly (PSM) describe the supply and disposition of petroleum products in the United States and major US geographic regions. The data series describe production, imports and exports, inter-Petroleum Administration for Defense (PAD) District movements, and inventories by the primary suppliers of petroleum products in the United States (50 States and the District of Columbia). The reporting universe includes those petroleum sectors in primary supply. Included are: petroleum refiners, motor gasoline blenders, operators of natural gas processing plants and fractionators, inter-PAD transporters, importers, and major inventory holders of petroleum products and crude oil. When aggregated, the data reported by these sectors approximately represent the consumption of petroleum products in the United States. Data presented in the PSM are divided into two sections: Summary Statistics and Detailed Statistics.

  20. Petroleum supply monthly, August 1993

    Energy Technology Data Exchange (ETDEWEB)

    1993-09-01

    This publication the Petroleum Supply Monthly (PSM) is one of a family of four publications produced by the Petroleum Supply Division within the Energy Information Administration (EIA) reflecting different levels of data timeliness and completeness. The other publications are the Weekly Petroleum Status Report, (WPSR), the Winter Fuels Report, and the Petroleum Supply Annual (PSA). Data presented describe the supply and disposition of petroleum products in the United States and major US geographic regions. The data series describe production, imports and exports, inter-Petroleum Administration for Defense (PAD) District movements, and inventories by the primary suppliers of petroleum products in the United States (50 States and the District of Columbia). The reporting universe includes those petroleum sectors in primary supply. Included are: petroleum refiners, motor gasoline blenders, operators of natural gas processing plants and fractionators, inter-PAD transporters, importers, and major inventory holders of petroleum products and crude oil. Data presented are divided into Summary Statistics and Detailed Statistics.