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Sample records for monitoring screen saver

  1. Design and implementation of a Bluetooth-based infant monitoring/saver (BIMS) system

    Science.gov (United States)

    Sonmez, Ahmet E.; Nalcaci, Murat T.; Pazarbasi, Mehmet A.; Toker, Onur; Fidanboylu, Kemal

    2007-04-01

    In this work, we discuss the design and implementation of a Bluetooth technology based infant monitoring system, which will enable the mother to monitor her baby's health condition remotely in real-time. The system will measure the heart rate, and temperature of the infant, and stream this data to the mother's Bluetooth based mobile unit, e.g. cell phone, PDA, etc. Existing infant monitors either require so many cables, or transmit only voice and/or video information, which is not enough for monitoring the health condition of an infant. With the proposed system, the mother will be warned against any abnormalities, which may be an indication of a disease, which in turn may result a sudden infant death. High temperature is a common symptom for several diseases, and heart rate is an essential sign of life, low or high heart rates are also essentials symptoms. Because of these reasons, the proposed system continously measures these two critical values. A 12 bits digital temperature sensor is used to measure infant's body temperature, and a piezo film sensor is used measure infant's heartbeat rate. These sensors, some simple analog circuitry, and a ToothPick unit are the main components of our embedded system. ToothPick unit is basically a Microchip 18LF6720 microcontroller, plus an RF circuitry with Bluetooth stack.

  2. When Things Do Not Go as Expected: Scenario Life Savers

    DEFF Research Database (Denmark)

    Dieckmann, Peter; Lippert, A.; Glavin, R.;

    2010-01-01

    In this paper we discuss scenario life savers - interventions before and during simulation scenarios that allow to create and use relevant learning opportunities, even if unexpected events happen during the conduction of the scenario. Scenario life savers are needed, when the comprehension or acc...

  3. When Things Do Not Go as Expected: Scenario Life Savers

    DEFF Research Database (Denmark)

    Dieckmann, Peter; Lippert, A.; Glavin, R.;

    2010-01-01

    In this paper we discuss scenario life savers - interventions before and during simulation scenarios that allow to create and use relevant learning opportunities, even if unexpected events happen during the conduction of the scenario. Scenario life savers are needed, when the comprehension...... or acceptance of the scenario by the participants is at stake, thus compromising learning opportunities. Scenario life savers can principally work by bringing participants back on track of the planned scenario or by adapting the conduction to their actions on the fly. Interventions can be within the logic...... of the scenario or from the "outside," not being part of the scenario itself. Scenario life savers should be anticipated during the design of scenarios and used carefully during their conduction, aiming to maximize the learning for participants. (Sim Healthcare 5: 219-225, 2010)...

  4. Fermilab energy saver refrigeration system tests

    Energy Technology Data Exchange (ETDEWEB)

    Theilacker, J.; Rode, C.; Makara, J.; Richied, D.; Leninger, M.; Ferry, R.; Mizicko, D.; Misek, J.

    1981-06-01

    The Energy Saver Refrigeration System is based on the concept of a central helium liquefier (5000 l/hr) providing liquid to 24 satellite refrigerators (966 W at 4.6/degree/K), which operate as amplifiers with a gain of 12. This concept was tested, cooling two 125 m long strings of superconducting magnets. The test was run using one satellite refrigerator operating as the ''central liquefier'', shipping liquid helium through a 250 m long transfer line to a second satellite refrigerator, which in turn cooled the magnets. In addition to testing the satellite concept, the heat loads of the magnets and transfer line were also measured. 3 refs.

  5. In-School Sustainability Action: Climate Clever Energy Savers

    Science.gov (United States)

    Buchanan, John; Schuck, Sandy; Aubusson, Peter

    2016-01-01

    The mandate for living sustainably is becoming increasingly urgent. This article reports on the Climate Clever Energy Savers (CCES) Program, a student-centred, problem- and project-based program in New South Wales, Australia, aimed at enabling school students to identify ways of reducing their schools' electricity consumption and costs. As part of…

  6. ICIS FE&C Compliance Monitoring Screens

    Data.gov (United States)

    U.S. Environmental Protection Agency — Web Based Training for Integrated Compliance Information System Updated Compliance Monitoring Training for ICIS Federal Enforcement and Compliance User. This...

  7. The Application of Quantum Energy Saver on Engine

    Directory of Open Access Journals (Sweden)

    Fang Xiong

    2016-01-01

    Full Text Available In order to reduce diesel fuel consumption, this paper conducts the research in view of a new type of quantum energy saving device, and then produce the sample and applied on automobile engine, Detect fuel use of an automobile by automobile fuel saving technology as-sessment methods from the department of transportation. Compare the changes of fuel use be-fore and after installation of quantum energy saving device on the same car, and give the feed-back of energy saving capability. The result shows, after installed quantum energy saver, both fuel consumption and the smoke of tail gas has decreased. The analysis and application of this paper carry out the conclusion that the quantum energy saver can play an important role in en-ergy saving and emission reduction, and provide a reference for other related research.

  8. The HeartSaver left ventricular assist device: an update.

    Science.gov (United States)

    Hendry, P J; Mussivand, T V; Masters, R G; Bourke, M E; Guiraudon, G M; Holmes, K S; Day, K D; Keon, W J

    2001-03-01

    Ventricular assist devices have been shown to be effective as bridges to transplantation and recovery for patients with end-stage heart failure. Current technology has been limited because of the need for percutaneous connections with controllers. The HeartSaver ventricular assist device (VAD) (World Heart Corporation, Ottawa, Ontario, Canada) was developed with the intention of having a completely implantable, portable VAD system. The system consists of an electrohydraulic blood pump, internal and external battery power, and a transcutaneous energy transfer and telemetry unit that allows for power transmission through the skin. Control of the device may be achieved locally or remotely through a variety of communication systems. The device has been modified with the Series II preclinical version being available for in vitro (mock loop) and in vivo (bovine model) testing. Seventeen Series II devices have been functional on mock loops or other testing trials for an accumulated 900 days of operation. There have been eight acute experiments using a bovine model to test various components as they have become available from manufacturing. Mean pump output was 10.4 +/- 1.1 L/min in full-fill/full-eject mode. Changes in the last 24 months include (1) cannula redesign for better port alignment and integration of tissue valves; (2) battery redesign to convert to new lithium-ion cells; (3) optimized infrared information and electromagnetic inductance energy transmission through various skin thicknesses and pigmentation; and (4) improved reliability of internal and external controller hardware and software. Modifications have been required to optimize the HeartSaver VAD's performance. The final HeartSaver VAD design will be produced in the near future to allow for formal in vitro and in vivo testing before clinical implantation.

  9. Cell saver filtering of extravasated rhBMP-2 after degenerative scoliosis reconstruction

    Directory of Open Access Journals (Sweden)

    Gabriel Liu, MBBCh, MSc, FRCS, FAMS (Orth

    2015-06-01

    Full Text Available RhBMP-2 is a bone fusion enhancer commonly used in scoliosis reconstruction surgery. It is delivered via an absorbable collagen sponge but has been known to migrate away from its delivery site. RhBMP-2 extravasation in surgical drainage has been noted during first two days post-surgery. Cell savers are widely used in scoliosis reconstruction to limit transfusion requirements and are commonly deployed in cases where rhBMP-2 is used for fusion augmentation. It is not known whether rhBMP-2 is present in salvaged blood or filtered away during cell saver recycling. Through this case series of four patients who underwent scoliosis reconstruction, we assess cell saver efficacy in filtering rhBMP-2 molecules by quantifying the amount of rhBMP-2 present in salvaged blood obtained after postoperative drainage recycling by OrthoPAT® cell saver and comparing it to rhBMP-2 leakage in postoperative drainage without cell saver recycling. We report an almost 10-fold reduction of rhBMP-2 concentration in salvaged blood obtained after cell saver recycling of postoperative drainage, suggesting cell saver effectiveness in filtering rhBMP-2 molecules.

  10. The Quantum Energy Saver design and Fuel-saving application

    Science.gov (United States)

    Fang, Xiong; Mao, Wenwu; Shen, Xisheng; LI, Jianyu; Huang, Wenchao; Chen, Zhixin

    2016-11-01

    In order to reduce the high fuel consumption of the shipping industry, a new type of quantum energy saver device is studied and developed. According to a period of time to use the energy saving device and the users’ feedback, by recording the fuel consumption of diesel engine usage, and comparing the changes in fuel consumption before and after the installation of quantum economizer in the same ship, it can reflected the ability of the fuel consumption. After analyzing the data, it shows that the installation of quantum economizer can significantly reduce the fuel consumption of a diesel engine ship. The analysis and application of this paper can play an important role in saving energy and reducing consumption, and provide a reference for other related research.

  11. Validity of Alternative Cut-Off Scores for the Back-Saver Sit and Reach Test

    Science.gov (United States)

    Looney, Marilyn A.; Gilbert, Jennie

    2012-01-01

    The purpose of the study was to determine if currently used FITNESSGRAM[R] cut-off scores for the Back Saver Sit and Reach Test had the best criterion-referenced validity evidence for 6-12 year old children. Secondary analyses of an existing data set focused on the passive straight leg raise and Back Saver Sit and Reach Test flexibility scores of…

  12. Reducing stillbirths: screening and monitoring during pregnancy and labour

    Directory of Open Access Journals (Sweden)

    Darmstadt Gary L

    2009-05-01

    Full Text Available Abstract Background Screening and monitoring in pregnancy are strategies used by healthcare providers to identify high-risk pregnancies so that they can provide more targeted and appropriate treatment and follow-up care, and to monitor fetal well-being in both low- and high-risk pregnancies. The use of many of these techniques is controversial and their ability to detect fetal compromise often unknown. Theoretically, appropriate management of maternal and fetal risk factors and complications that are detected in pregnancy and labour could prevent a large proportion of the world's 3.2 million estimated annual stillbirths, as well as minimise maternal and neonatal morbidity and mortality. Methods The fourth in a series of papers assessing the evidence base for prevention of stillbirths, this paper reviews available published evidence for the impact of 14 screening and monitoring interventions in pregnancy on stillbirth, including identification and management of high-risk pregnancies, advanced monitoring techniques, and monitoring of labour. Using broad and specific strategies to search PubMed and the Cochrane Library, we identified 221 relevant reviews and studies testing screening and monitoring interventions during the antenatal and intrapartum periods and reporting stillbirth or perinatal mortality as an outcome. Results We found a dearth of rigorous evidence of direct impact of any of these screening procedures and interventions on stillbirth incidence. Observational studies testing some interventions, including fetal movement monitoring and Doppler monitoring, showed some evidence of impact on stillbirths in selected high-risk populations, but require larger rigourous trials to confirm impact. Other interventions, such as amniotic fluid assessment for oligohydramnios, appear predictive of stillbirth risk, but studies are lacking which assess the impact on perinatal mortality of subsequent intervention based on test findings. Few rigorous

  13. MNAtoolbox: A Monitored Natural Attenuation Site Screening Program

    Energy Technology Data Exchange (ETDEWEB)

    Borns, David J.; Brady, Patrick V.; Brady, Warren D.; Krupka, Kenneth M.; Spalding, Brian P.; Waters, Robert D.; Zhang, Pengchu

    1999-07-12

    Screening of sites for the potential application and reliance upon monitored natural attenuation (MNA) can be done using MNAtoolbox, a web-based tool for estimating extent of biodegradation, chemical transformation, and dilution. MNAtoolbox uses site-specific input data, where available (default parameters are taken from the literature), to roughly quantify the nature and extent of attenuation at a particular site. Use of MNAtoolbox provides 3 important elements of site evaluation: (1) Identifies likely attenuation pathways, (2) Clearly identifies sites where MNA is inappropriate, and (3) Evaluates data requirements for subsequent reliance on MNA as a sole or partial corrective action.

  14. Monitored retrievable storage facility site screening and evaluation report

    Energy Technology Data Exchange (ETDEWEB)

    none,

    1985-05-01

    The Nuclear Waste Policy Act of 1982 directs the Department of Energy to complete a detailed study of the need for and feasibility of, and to submit to the Congress a proposal for, the construction of one or more monitored retrievable storage facilities for high level radioactive waste and spent nuclear fuel.'' The Act directs that the proposal includes site specific designs. Further, the proposal is to include, for the first such facility, at least three alternative sites and at least five alternative combinations of such proposed site and facility designs...'' as well as a recommendation of the combination among the alternatives that the Secretary deems preferable.'' An MRS Site Screening Task Force has been formed to help identify and evaluated potential MRS facility sites within a preferred region and with the application of a siting process and criteria developed by the DOE. The activities of the task force presented in this report includes: site screening (Sections 3, 4, and 5), the MRS facilities which are to be sited are described; the criteria, process and outcome of the screening process is presented; and descriptions of the candidate MRS facility sites are given, and site evaluations (Sections 6 through 9) where the rational for the site evaluations are presented, along with each evaluation and findings of the Task Force.

  15. Development of Powered Disk Type Sugar Cane Stubble Saver

    Directory of Open Access Journals (Sweden)

    Radite P.A.S.

    2009-04-01

    Full Text Available The objective of this research was to design, fabricate and test a prototype of sugar cane stubble saver based on powered disk mechanism. In this research, a heavy duty disk plow or disk harrow was used as a rotating knife to cut the sugarcane stubble. The parabolic disk was chosen because it is proven reliable as soil working tools and it is available in the market as spare part of disk plow or disk harrow unit. The prototype was mounted on the four wheel tractor’s three point hitch, and powered by PTO of the tractor. Two kinds of disks were used in these experiments, those were disk with regular edge or plain disk and disk with scalloped edge or scalloped disk. Both disks had diameter of 28 inch. Results of field test showed that powered disk mechanism could satisfy cut sugar cane’s stubble. However, scalloped disk type gave smoother stubble cuts compared to that of plain disk. Plain disk type gave broken stubble cut. Higher rotation (1000 rpm resulted better cuts as compared to lower rotation (500 rpm both either on plain disk and scalloped disk. The developed prototype could work below the soil surface at depth of 5 to 10 cm. With tilt angle setting 20O and disk angle 45O the width of cut was about 25 cm.

  16. Monitored retrievable storage facility site screening and evaluation report

    Energy Technology Data Exchange (ETDEWEB)

    none,

    1985-05-01

    The Nuclear Waste Policy Act of 1982 directs the Department of Energy to complete a detailed study of the need for and feasibility of, and to submit to the Congress a proposal for, the construction of one or more monitored retrievable storage facilities for high level radioactive waste and spent nuclear fuel.'' The Act directs that the proposal includes site specific designs. Further, the proposal is to include, for the first such facility, at least three alternative sites and at least five alternative combinations of such proposed sites and facility designs{hor ellipsis}'' as well as a recommendation of the combination among the alternatives that the Secretary deems preferable.'' An MRS Site Screening Task Force has been formed to help identify and evaluate potential MRS facility sites within a preferred region and with the application of a siting process and criteria developed by the DOE. The activities of the Task Force presented in this report include: site evaluations (sections 10 through 12) where the rationale for the site evaluations are presented, along with each evaluation and findings of the Task Force. This in Volume 2 of a three volume document.

  17. Monitored Retrievable Storage facility site screening and evaluation report

    Energy Technology Data Exchange (ETDEWEB)

    none,

    1985-05-01

    The Nuclear Waste Policy Act of 1982 directs the Department of Energy to complete a detailed study of the need for and feasibility of, and to submit to the Congress a proposal for, the construction of one or more monitored retrievable storage facilities for high level radioactive waste and spent nuclear fuel.'' The Act directs that the proposal includes site specific designs. Further, the proposal is to include, for the first such facility, at least three alternative sites and at least five alternative combinations of such proposed sites and facility designs {hor ellipsis}'' as well as a recommendation of the combination among the alternatives that the Secretary deems preferable.'' An MRS Site Screening Task Force has been formed to help identify and evaluate potential MRS facility sites within a preferred region and with the application of a siting process and criteria developed by the DOE. The activities of the Task Force presented in this report, all site evaluations (sections 13 through 16) where the rationale for the site evaluations are presented, along with each evaluation and findings of the Task Force. This is Volume 3 of a three volume document. References are also included in this volume.

  18. 78 FR 9936 - Federal Housing Administration (FHA): PowerSaver Home Energy Retrofit Loan Pilot Program...

    Science.gov (United States)

    2013-02-12

    ..., 2011, HUD published a notice at 76 FR 17936 that announced HUD's FHA Home Energy Retrofit Loan Pilot... URBAN DEVELOPMENT Federal Housing Administration (FHA): PowerSaver Home Energy Retrofit Loan Pilot Program: Extension of Pilot Program AGENCY: Office of the Assistant Secretary for Housing--Federal...

  19. Validation of a model to estimate personalised screening frequency to monitor diabetic retinopathy

    NARCIS (Netherlands)

    Heijden, A.A. van der; Walraven, I.; Riet, E. van 't; Aspelund, T.; Lund, S.H.; Elders, P.; Polak, B.C.P.; Moll, A.C.; Keunen, J.E.E.; Dekker, J.M.; Nijpels, G.

    2014-01-01

    AIMS/HYPOTHESIS: Our study aimed to validate a model to determine a personalised screening frequency for diabetic retinopathy. METHODS: A model calculating a personalised screening interval for monitoring retinopathy based on patients' risk profile was validated using the data of 3,319 type 2 diabet

  20. Disposable Screen Printed Electrochemical Sensors: Tools for Environmental Monitoring

    Directory of Open Access Journals (Sweden)

    Akhtar Hayat

    2014-06-01

    Full Text Available Screen printing technology is a widely used technique for the fabrication of electrochemical sensors. This methodology is likely to underpin the progressive drive towards miniaturized, sensitive and portable devices, and has already established its route from “lab-to-market” for a plethora of sensors. The application of these sensors for analysis of environmental samples has been the major focus of research in this field. As a consequence, this work will focus on recent important advances in the design and fabrication of disposable screen printed sensors for the electrochemical detection of environmental contaminants. Special emphasis is given on sensor fabrication methodology, operating details and performance characteristics for environmental applications.

  1. Efficiency and Cost Analysis of Cell Saver Auto Transfusion System in Total Knee Arthroplasty

    Science.gov (United States)

    Bilgili, Mustafa Gökhan; Erçin, Ersin; Peker, Gökhan; Kural, Cemal; Başaran, Serdar Hakan; Duramaz, Altuğ; Avkan, Cevdet

    2014-01-01

    Background: Blood loss and replacement is still a controversial issue in major orthopaedic surgery. Allogenic blood transfusion may cause legal problems and concerns regarding the transmission of transfusion-related diseases. Cellsaver Systems (CSS) were developed as an alternative to allogenic transfusion but CSS transfusion may cause coagulation, infection and haemodynamic instability. Aims: Our aim was to analyse the efficiency and cost analysis of a cell saver auto-transfusion system in the total knee arthroplasty procedure. Study Design: Retrospective comparative study. Methods: Those patients who were operated on by unilateral, cemented total knee arthroplasty (TKA) were retrospectively evaluated. Group 1 included 37 patients who were treated using the cell saver system, and Group 2 involved 39 patients who were treated by allogenic blood transfusion. The groups were compared in terms of preoperative haemoglobin and haematocrit levels, blood loss and transfusion amount, whether allogenic transfusion was made, degree of deformity, body mass index and cost. Results: No significant results could be obtained in the statistical comparisons made in terms of the demographic properties, deformity properties, preoperative laboratory values, transfusion amount and length of hospital stay of the groups. Average blood loss was calculated to be less in Group 1 (p<0.05) and cost was higher in Group 1 (p<0.05). Conclusion: Cell saver systems do not decrease the amount of allogenic blood transfusion and costs more. Therefore, the routine usage of the auto-transfusion systems is a controversial issue. Cell saver system usage does not affect allogenic blood transfusion incidence or allogenic blood transfusion volume. It was found that preoperative haemoglobin and body mass index rates may affect allogenic blood transfusion. Therefore, it is foreseen that auto-transfusion systems could be useful in patients with low haemoglobin level and body mass index. PMID:25207187

  2. Energy Saver: Tips on Saving Energy and Money in Your Home

    Energy Technology Data Exchange (ETDEWEB)

    Casey, Allison L [National Renewable Energy Laboratory (NREL), Golden, CO (United States)

    2017-10-04

    This guide shows you how easy it is to reduce your energy use at home and on the road. You'll find quick tips you can use to start saving today, as well as information on larger projects that will help save you money over the long term. Find even more information about saving money and energy at home by visiting our website, EnergySaver.gov.

  3. Documentation of Calculation Methodology, Input data, and Infrastructure for the Home Energy Saver Web Site

    Energy Technology Data Exchange (ETDEWEB)

    Pinckard, Margaret J.; Brown, Richard E.; Mills, Evan; Lutz, James D.; Moezzi, Mithra M.; Atkinson, Celina; Bolduc, Chris; Homan, Gregory K.; Coughlin, Katie

    2005-07-13

    The Home Energy Saver (HES, http://HomeEnergySaver.lbl.gov) is an interactive web site designed to help residential consumers make decisions about energy use in their homes. This report describes the underlying methods and data for estimating energy consumption. Using engineering models, the site estimates energy consumption for six major categories (end uses); heating, cooling, water heating, major appliances, lighting, and miscellaneous equipment. The approach taken by the Home Energy Saver is to provide users with initial results based on a minimum of user input, allowing progressively greater control in specifying the characteristics of the house and energy consuming appliances. Outputs include energy consumption (by fuel and end use), energy-related emissions (carbon dioxide), energy bills (total and by fuel and end use), and energy saving recommendations. Real-world electricity tariffs are used for many locations, making the bill estimates even more accurate. Where information about the house is not available from the user, default values are used based on end-use surveys and engineering studies. An extensive body of qualitative decision-support information augments the analytical results.

  4. Automated video screening for unattended background monitoring in dynamic environments.

    Energy Technology Data Exchange (ETDEWEB)

    Carlson, Jeffrey J.

    2004-03-01

    This report addresses the development of automated video-screening technology to assist security forces in protecting our homeland against terrorist threats. A threat of specific interest to this project is the covert placement and subsequent remote detonation of bombs (e.g., briefcase bombs) inside crowded public facilities. Different from existing video motion detection systems, the video-screening technology described in this report is capable of detecting changes in the static background of an otherwise, dynamic environment - environments where motion and human activities are persistent. Our goal was to quickly detect changes in the background - even under conditions when the background is visible to the camera less than 5% of the time. Instead of subtracting the background to detect movement or changes in a scene, we subtracted the dynamic scene variations to produce an estimate of the static background. Subsequent comparisons of static background estimates are used to detect changes in the background. Detected changes can be used to alert security forces of the presence and location of potential threats. The results of this research are summarized in two MS Power-point presentations included with this report.

  5. Nuclear Material Monitoring System (NMMS) for security screens

    Energy Technology Data Exchange (ETDEWEB)

    Hyun Kim, Kwang, E-mail: radkim@jwu.ac.kr [Faculty of Biomedical Engineering, Jungwon University, 5 Goesan-eup, Goesan-gun, Chungcheongbuk-do 367-805 (Korea, Republic of); Hong Chang, Ji [Faculty of Biomedical Engineering, Jungwon University, 5 Goesan-eup, Goesan-gun, Chungcheongbuk-do 367-805 (Korea, Republic of); Hyun Jung, Young [Department of Radiological Science, Yonsei University, Wonju (Korea, Republic of)

    2011-08-21

    As a Nuclear Material Monitoring System (NMMS), two large-volume plastic detectors and a NaI detector for gamma-ray sources and two He-3 tubes for neutron sources were integrated in a mobile box that can be mounted on a vehicle. Custom-made preamplifiers, shapers, and a MCA (Multi-Channel Analyzer) for each detector were conceived of and built on a compact circuit board to collect and integrate different types of data from each detector. The collected data, counts rates and spectra of the detected radiation, were continually monitored and plotted on several user-friendly display windows on a laptop computer. The system performance in the vehicle-mounted condition was tested for Co-60, Cs-137, and Cf-252 sources at various distances and speeds.

  6. Restless legs syndrome: diagnostic time-savers, Tx tips.

    Science.gov (United States)

    Moyer, Darlene E; Zayas-Bazan, Javier; Reese, Gary

    2009-08-01

    To diagnose restless legs syndrome (RLS), start with the 4 "essential criteria": (1) a powerful urge to move the legs that is (2) rest-induced, (3) improves with activity, and (4) worsens in the evening. Carefully screen for secondary causes of RLS, including renal failure, pregnancy, iron deficiency, and medications that can cause or exacerbate symptoms. Carbidopa/levodopa is the first-line treatment for patients with intermittent symptoms of RLS; dopamine agonists are recommended for those with daily or refractory symptoms.

  7. Quality screening for air quality monitoring data in China.

    Science.gov (United States)

    Liu, Jianzheng; Li, Weifeng; Li, Jie

    2016-09-01

    Particulate matter data obtained from the national air quality monitoring network in China has become an essential and critical data source for many current and forthcoming studies as well as the formulation and implementation of air pollution regulatory policies on particulate matter (PM2.5 and PM10). However, the quality control of this data is dubitable and can affect many future studies and policies. This study identifies and elucidates two significant quality control issues with the data. They are PM2.5 levels exceeding concurrent co-located PM10 levels and the registration of same concentrations for consecutive hours at some stations. Future studies utilizing particulate matter data need to acknowledge and address these issues to ensure accurate and reliable results.

  8. Vancomycin added to the wash solution of the cell-saver. Effect on bacterial contamination.

    Science.gov (United States)

    Perez-Ferrer, A; Gredilla-Díaz, E; de Vicente-Sánchez, J; Navarro-Suay, R; Gilsanz-Rodríguez, F

    2017-04-01

    The aim of this study is to test whether the addition of a low-dose of antibiotic (vancomycin) to the wash solution (saline) of the cell-saver reduces the incidence of bacterial contamination of the autologous red blood cell (RBCs) concentrate recovered. Experimental, randomized, double-blind, parallel group study performed on 20 consecutive patients scheduled for posterior spinal fusion surgery. Intraoperative bleeding was processed through a cell-saver: HaemoLite(®) 2+, in which the RBCs were washed according to randomization group, with saline (control group) or saline+10μg/ml(-1) vancomycin (vanco group). Data regarding age, weight, processed and recovered volume, blood count, blood culture, and vancomycin concentration in RBCs concentrates obtained and incidence of fever after reinfusion were collected. Processed volume was 843±403ml and recovered volume 121±29ml, with haemoglobin concentration 10.4±5.0g/dl(-1) and haematocrit 29.1±15.9% (mean±SD). Recovered RBC concentrate cultures were positive for coagulase-negative Staphylococcus in 5 cases (50%) of the control group while all cultures were negative in the vanco group (P=.016). The difference between the theoretical concentration of vancomycin administered and the concentration determined in the recovered RBC concentrate was 1.31μg/ml(-1) (95% CI 1.19 to 1.43; P=.074). The addition of vancomycin at a concentration of 10ug/ml(-1) to the wash solution of the cell-saver achieved similar concentrations in the autologous blood concentrate recovered allowing for bacterial removal, with negative blood cultures in all cases. Copyright © 2016 Sociedad Española de Anestesiología, Reanimación y Terapéutica del Dolor. Publicado por Elsevier España, S.L.U. All rights reserved.

  9. Screen printed flexible radiofrequency identification tag for oxygen monitoring.

    Science.gov (United States)

    Martínez-Olmos, A; Fernández-Salmerón, J; Lopez-Ruiz, N; Rivadeneyra Torres, A; Capitan-Vallvey, L F; Palma, A J

    2013-11-19

    In this work, a radiofrequency identification (RFID) tag with an optical indicator for the measurement of gaseous oxygen is described. It consists of an O2 sensing membrane of PtOEP together with a full electronic system for RFID communication, all printed on a flexible substrate. The membrane is excited by an LED at 385 nm wavelength and the intensity of the luminescence generated is registered by means of a digital color detector. The output data corresponding to the red coordinate of the RGB color space is directly related to the concentration of O2, and it is sent to a microcontroller. The RFID tag is designed and implemented by screen printing on a flexible substrate for the wireless transmission of the measurement to a remote reader. It can operate in both active and passive mode, obtaining the power supply from the electromagnetic waves of the RFID reader or from a small battery, respectively. This system has been fully characterized and calibrated including temperature drifts, showing a high-resolution performance that allows measurement of very low values of oxygen content. Therefore this system is perfectly suitable for its use in modified atmosphere packaging where the oxygen concentration is reduced below 2%. As the reading of the O2 concentration inside the envelope is carried out with an external RFID reader using wireless communication, there is no need for perforations for probes or wires, so the packaging remains completely closed. With the presented device, a limit of detection of 40 ppm and a resolution as low as 0.1 ppm of O2 can be reached with a low power consumption of 3.55 mA.

  10. OPTIMAL WELL LOCATOR (OWL): A SCREENING TOOL FOR EVALUATING LOCATIONS OF MONITORING WELLS

    Science.gov (United States)

    The Optimal Well Locator ( OWL) program was designed and developed by USEPA to be a screening tool to evaluate and optimize the placement of wells in long term monitoring networks at small sites. The first objective of the OWL program is to allow the user to visualize the change ...

  11. Celiac Disease in Adult Patients: Specific Autoantibodies in the Diagnosis, Monitoring, and Screening

    Directory of Open Access Journals (Sweden)

    Evagelia Trigoni

    2014-01-01

    Full Text Available The increasing prevalence of celiac disease (CD, especially in adults, its atypical clinical presentation, and the strict, lifelong adherence to gluten-free diet (GFD as the only option for healthy state create an imperative need for noninvasive methods that can effectively diagnose CD and monitor GFD. Aim. Evaluation of anti-endomysium (EmA and anti-tissue transglutaminase IgA (tTG-A antibodies in CD diagnosis, GFD monitoring, and first degree relatives screening in CD adult patients. Methods. 70 newly diagnosed Greek adult patients, 70 controls, and 47 first degree relatives were tested for the presence of EmA and tTG-A. The CD patients were monitored during a 3-year period. Results. EmA predictive ability for CD diagnosis was slightly better compared to tTG-A (P=0.043. EmA could assess compliance with GFD already from the beginning of the diet, while both EmA and tTG-A had an equal ability to discriminate between strictly and partially compliant patients after the first semester and so on. Screening of first degree relatives resulted in the identification of 2 undiagnosed CD cases. Conclusions. Both EmA and tTG-A are suitable markers in the CD diagnosis, in the screening of CD among first degree relatives, having also an equal performance in the long term monitoring.

  12. Celiac disease in adult patients: specific autoantibodies in the diagnosis, monitoring, and screening.

    Science.gov (United States)

    Trigoni, Evagelia; Tsirogianni, Alexandra; Pipi, Elena; Mantzaris, Gerassimos; Papasteriades, Chryssa

    2014-01-01

    The increasing prevalence of celiac disease (CD), especially in adults, its atypical clinical presentation, and the strict, lifelong adherence to gluten-free diet (GFD) as the only option for healthy state create an imperative need for noninvasive methods that can effectively diagnose CD and monitor GFD. Aim. Evaluation of anti-endomysium (EmA) and anti-tissue transglutaminase IgA (tTG-A) antibodies in CD diagnosis, GFD monitoring, and first degree relatives screening in CD adult patients. Methods. 70 newly diagnosed Greek adult patients, 70 controls, and 47 first degree relatives were tested for the presence of EmA and tTG-A. The CD patients were monitored during a 3-year period. Results. EmA predictive ability for CD diagnosis was slightly better compared to tTG-A (P = 0.043). EmA could assess compliance with GFD already from the beginning of the diet, while both EmA and tTG-A had an equal ability to discriminate between strictly and partially compliant patients after the first semester and so on. Screening of first degree relatives resulted in the identification of 2 undiagnosed CD cases. Conclusions. Both EmA and tTG-A are suitable markers in the CD diagnosis, in the screening of CD among first degree relatives, having also an equal performance in the long term monitoring.

  13. Computer screen saver hand hygiene information curbs a negative trend in hand hygiene behavior

    NARCIS (Netherlands)

    K. Helder MScN (Onno); J.W.M. Weggelaar-Jansen (Anne Marie); D.J.C. Waarsenburg (Daniël); C.W.N. Looman (Caspar); J.B. van Goudoever (Hans); J. Brug (Hans); R.F. Kornelisse (René)

    2012-01-01

    markdownabstract__Abtract__ Background: Appropriate hand hygiene among health care workers is the most important infection prevention measure; however, compliance is generally low. Gain-framed messages (ie, messages that emphasize the benefits of hand hygiene rather than the risks of

  14. Computer screen saver hand hygiene information curbs a negative trend in hand hygiene behavior

    NARCIS (Netherlands)

    K. Helder MScN (Onno); J.W.M. Weggelaar-Jansen (Anne Marie); D.J.C. Waarsenburg (Daniël); C.W.N. Looman (Caspar); J.B. van Goudoever (Hans); J. Brug (Hans); R.F. Kornelisse (René)

    2012-01-01

    markdownabstract__Abtract__ Background: Appropriate hand hygiene among health care workers is the most important infection prevention measure; however, compliance is generally low. Gain-framed messages (ie, messages that emphasize the benefits of hand hygiene rather than the risks of noncompliance)

  15. CERN Physics Screen Saver: Help LHC tracking studies on your PC

    CERN Multimedia

    2004-01-01

    Many PC users are familiar with screensavers such as SETI@home and FightAIDS@home. These screensavers take advantage of times when your PC is idle to do useful computing on a particular scientific problem. SETI@home, which analyses radio-astronomy data for signs of extraterrestrial intelligence, has been downloaded by over 5 million people. Similar programs are now sold commercially, and installed in major corporations to provide extra computing power at low cost. CERN 's IT Department is interested in evaluating this sort of technology for the future. Most of the scientific computing challenges that the LHC experiments are facing will require access to large amounts of storage, and cannot be run on individual PCs. However, there are exceptions. A program called SixTrack, which simulates particles traveling around the LHC to study the stability of their orbits, can fit on a single PC and requires relatively little input or output. SixTrack, which was developed by Frank Schmidt of the AB Department, produces r...

  16. Site Screening and Technical Guidance for Monitored Natural Attenuation at DOE Sites

    Energy Technology Data Exchange (ETDEWEB)

    Borns, D.J.; Brady, P.V.; Brady, W.D.; Krupka, K.M.; Spalding, B.P.; Waters, R.D.; Zhang, P.

    1999-03-01

    Site Screening and Technical Guidance for Monitored Natural Attenuation at DOE Sites briefly outlines the biological and geochemical origins of natural attenuation, the tendency for natural processes in soils to mitigate contaminant transport and availability, and the means for relying on monitored natural attenuation (MNA) for remediation of contaminated soils and groundwaters. This report contains a step-by-step guide for (1) screening contaminated soils and groundwaters on the basis of their potential for remediation by natural attenuation and (2) implementing MNA consistent with EPA OSWER Directive 9200.4-17. The screening and implementation procedures are set up as a web-based tool (http://www.sandia.gov/eesector/gs/gc/na/mnahome.html) to assist US Department of Energy (DOE) site environmental managers and their staff and contractors to adhere to EPA guidelines for implementing MNA. This document is intended to support the Decision Maker's Framework Guide and Monitoring Guide both to be issued from DOE EM-40. Further technical advances may cause some of the approach outlined in this document to change over time.

  17. Salamander Saver

    Science.gov (United States)

    Ilseman, Kelly; Hoffmann, Kristine

    2016-01-01

    On a spring morning in Maine, traps made of nets rise above vernal pools in a small wetland, ready to collect salamanders. The traps were designed by groups of rural and urban high school students from Maine and Massachusetts participating in the University of Maine Upward Bound Math Science Program (UBMS) at the university campus in Orono, Maine.…

  18. Life Savers

    Institute of Scientific and Technical Information of China (English)

    MATTHEW PLOWRIGHT

    2008-01-01

    @@ When you're thinking about shiny gadgets to spend your hard-earned cash on, an external hard-drive is unlikely to feature high on your list. But if you've ever had the misfortune to suffer a computer crash so severe that it wipes all of your precious documents, photos, music, and programs, then you won't need to be told just how invaluable a reliable backup device for your computer can be. Here are three of the best.

  19. Energy Savers

    Institute of Scientific and Technical Information of China (English)

    2006-01-01

    The government has mandated a reduction in energy use this year, but many wonder whether and how that goal can be achieved Pressure is mounting for China to reduce its energy consumption, but many say the government's target of cutting energy use per unit of gross domestic product (GDP) by 4 percent this year will be a major hurdle. Nearly half of the provinces and

  20. Validation of the MediByte® Type 3 Portable Monitor Compared with Polysomnography for Screening of Obstructive Sleep Apnea

    Directory of Open Access Journals (Sweden)

    Helen S Driver

    2011-01-01

    Full Text Available BACKGROUND: Portable monitors are increasingly being used as a diagnostic screening tool for obstructive sleep apnea (OSA, and in-laboratory validation of these devices with polysomnography (PSG is required.

  1. Fluorescence assays for monitoring RNA-ligand interactions and riboswitch-targeted drug discovery screening.

    Science.gov (United States)

    Liu, J; Zeng, C; Zhou, S; Means, J A; Hines, J V

    2015-01-01

    Riboswitches and other noncoding regulatory RNA are intriguing targets for the development of therapeutic agents. A significant challenge in the drug discovery process, however, is the identification of potent compounds that bind the target RNA specifically and disrupt its function. Essential to this process is an effectively designed cascade of screening assays. A screening cascade for identifying compounds that target the T box riboswitch antiterminator element is described. In the primary assays, moderate to higher throughput screening of compound libraries is achieved by combining the sensitivity of fluorescence techniques with functionally relevant assays. Active compounds are then validated and the binding to target RNA further characterized in secondary assays. The cascade of assays monitor ligand-induced changes in the steady-state fluorescence of an attached dye or internally incorporated 2-aminopurine; the fluorescence anisotropy of an RNA complex; and, the thermal denaturation fluorescence profile of a fluorophore-quencher labeled RNA. While the assays described have been developed for T box riboswitch-targeted drug discovery, the fluorescence methods and screening cascade design principles can be applied to drug discovery efforts targeted toward other medicinally relevant noncoding RNA.

  2. Monitoring ribosomal frameshifting as a platform to screen anti-riboswitch drug candidates.

    Science.gov (United States)

    Yu, Chien-Hung; Olsthoorn, René C L

    2015-01-01

    Riboswitches are regions within mRNAs that can regulate downstream expression of genes through metabolite-induced alteration of their secondary structures. Due to the significant association of bacterial essential or virulence genes, bacterial riboswitches have become promising targets for development of putative antibacterial drugs. However, most of the screening systems to date are based on in vitro or bacterial systems, lacking the possibility to preobserve the adverse effects to the host's translation machinery. This chapter describes a novel screening method based on monitoring the riboswitch-induced -1 ribosomal frameshifting (-1 FS) efficiency in a mammalian cell-free lysate system using preQ1 class-I (preQ1-I) riboswitches as model target.

  3. Validity and reliability of the Back-Saver Sit and Reach in girls aged 7-8 years.

    OpenAIRE

    Boneth-Collante, Milena; Ariza-García, Claudia Lucía; Corredor-Vargas, Julián David; Villamizar-Niño, Andrea Paola; Hijuelos-Cárdenas, Martha Liliana

    2015-01-01

    Background: The back saver sit and reach (BSSR) test is probably the most frequently quantitative tool used to estimate hamstring flexibility in the school and physical-sporting field due to its simplicity and quickly implementation. However, there is limited scientific evidence to justify its use in colombian girls. Objective: To assess the validity and intra-rater reliability of the BSSR in girls of a school from Bucaramanga. Mathodology: A study of evaluation of diagnostic technology was d...

  4. The use of magnetic nanoparticles in thermal therapy monitoring and screening: Localization and imaging (invited).

    Science.gov (United States)

    Weaver, John B

    2012-04-01

    Magnetic nanoparticles have many diagnostic and therapeutic applications. A method termed magnetic spectroscopy of nanoparticle Brownian motion (MSB) was developed to interrogate in vivo the microscopic environment surrounding magnetic nanoparticles. We can monitor several effects that are important in thermal therapy and screening including temperature measurement and the bound state distribution. Here we report on simulations of nanoparticle localization. Measuring the spatial distribution of nanoparticles would allow us to identify ovarian cancer much earlier when it is still curable or monitor thermal therapies more accurately. We demonstrate that with well-designed equipment superior signal to noise ratio (SNR) can be achieved using only two harmonics rather than using all the harmonics containing signal. Alternatively, smaller magnetic field amplitudes can be used to achieve the same SNR. The SNR is improved using fewer harmonics because the noise is limited.

  5. The efficacy and cost-effectiveness of cell saver use in instrumented posterior correction and fusion surgery for scoliosis in school-aged children and adolescents.

    Science.gov (United States)

    Miao, Yu-Liang; Ma, Hua-Song; Guo, Wen-Zhi; Wu, Ji-Gong; Liu, Yan; Shi, Wen-Zhu; Wang, Xiao-Ping; Mi, Wei-Dong; Fang, Wei-Wu

    2014-01-01

    Posterior spinal instrumentation and fusion surgery in school-aged children and adolescents is associated with the potential for massive intraoperative blood loss, which requires significant allogeneic blood transfusion. Until now, the intraoperative use of the cell saver has been extensively adopted; however, its efficacy and cost-effectiveness have not been well established. Therefore, the aim of this study is to determine the efficacy and cost-effectiveness of intraoperative cell saver use. This study was a single-center, retrospective study of 247 school-aged and adolescent patients who underwent posterior spinal instrumentation and fusion surgery between August 2007 and June 2013. A cell saver was used intraoperatively in 67 patients and was not used in 180 patients. Matched case-control pairs were selected using a propensity score to balance potential confounders in baseline characteristics. Allogeneic red blood cell (RBC) and plasma transfusions as well as blood transfusion costs were analyzed. The propensity score matching produced 60 matched pairs. Compared to the control group, the cell saver group had significantly fewer intraoperative allogeneic RBC transfusions (P = 0.012). However, when the combined postoperative and total perioperative periods were evaluated for the use of allogeneic RBC transfusion, no significant differences were observed between the two groups (P = 0.813 and P = 0.101, respectively). With regard to the total cost of perioperative transfusion of all blood products (RBC and plasma), costs for the control group were slightly lower than those of the cell saver group, but this variance did not reach statistical significance (P = 0.095). The use of the cell saver in posterior spinal instrumentation and fusion surgery in school-aged children and adolescents was able to decrease the amount of intraoperative allogeneic RBC transfusion but failed to decrease total perioperative allogeneic RBC transfusion. Moreover, the use of the cell saver

  6. The role of the saver in a HPLCs heat transfer process: a transient analysis

    Science.gov (United States)

    Lorenzini, M.; Valdiserri, P.; Pagnoni, M.

    2017-01-01

    This work describes the experimental validation of a mathematical model implemented in Matlab/Simulink®, which is used to investigate energy consumption in the production process of high-pressure laminate composites (HPLCs). First, experimental onsite temperature measurements are used to determine parameters for the core component, i.e. the package, consisting of several layers of different materials. These otherwise hard to assess quantities are the generated power due to exothermal reactions in the cross-linking phase, and the piecewise approximation for the variable heat capacity of the impregnated paper over the heating phase of the process. The capability of the whole model (including the hot and cold water storage tanks) to replicate the behaviour of the actual production process has been verified. The validated model has been employed to investigate the influence of a saver tank for the spent hot water to be employed in the early stage of the heating phase of the process, with the load and discharge phases lasting three or five minutes each. Computations demonstrate that significant savings in energy (up to 34) can be obtained.

  7. Labour saver or building a cohesive interprofessional team? The role of the nurse practitioner within hospitals.

    Science.gov (United States)

    Hurlock-Chorostecki, Christina; Forchuk, Cheryl; Orchard, Carole; van Soeren, Mary; Reeves, Scott

    2014-05-01

    Nurse practitioners (NP) are employed within hospital interprofessional (IP) teams in several countries worldwide. There have been some efforts to describe the nature of the NP role within IP teams largely focussing on how the role may augment care processes. Here, using a constructivist grounded theory approach, the perceptions of NPs about their role were compared and integrated into a previously published team perspective as the second phase of a larger study. Seventeen hospital-based (HB) NPs across Ontario, Canada, participated in group and individual interviews. The NP perspective substantiated and expanded the previously reported team perspective, resulting in an IP perspective. The three practice foci illustrating role value meaning of this perspective became: evolve NP role and advance the specialty, focus on team working, and hold patient care together. The IP perspective, juxtaposed with an existing contingency approach, revealed that NPs were promoting IP work, predominantly at the collaboration and teamwork levels, and aiding IP team transitions to appropriate forms of IP work. The practice, "focus on team working"' was strongly related to promoting IP work. The findings were consistent with HB NPs enacting a role in building IP team cohesiveness rather than merely acting as a labour saver. This is the first study to align NP and team understanding of HB NP role value using an IP framework.

  8. Plasma nitriding monitoring reactor: A model reactor for studying plasma nitriding processes using an active screen

    Energy Technology Data Exchange (ETDEWEB)

    Hamann, S., E-mail: hamann@inp-greifswald.de; Röpcke, J. [INP-Greifswald, Felix-Hausdorff-Str. 2, 17489 Greifswald (Germany); Börner, K.; Burlacov, I.; Spies, H.-J. [TU Bergakademie Freiberg, Institute of Materials Engineering, Gustav-Zeuner-Str. 5, 09599 Freiberg (Germany); Strämke, M.; Strämke, S. [ELTRO GmbH, Arnold-Sommerfeld-Ring 3, 52499 Baesweiler (Germany)

    2015-12-15

    A laboratory scale plasma nitriding monitoring reactor (PLANIMOR) has been designed to study the basics of active screen plasma nitriding (ASPN) processes. PLANIMOR consists of a tube reactor vessel, made of borosilicate glass, enabling optical emission spectroscopy (OES) and infrared absorption spectroscopy. The linear setup of the electrode system of the reactor has the advantages to apply the diagnostic approaches on each part of the plasma process, separately. Furthermore, possible changes of the electrical field and of the heat generation, as they could appear in down-scaled cylindrical ASPN reactors, are avoided. PLANIMOR has been used for the nitriding of steel samples, achieving similar results as in an industrial scale ASPN reactor. A compact spectrometer using an external cavity quantum cascade laser combined with an optical multi-pass cell has been applied for the detection of molecular reaction products. This allowed the determination of the concentrations of four stable molecular species (CH{sub 4}, C{sub 2}H{sub 2}, HCN, and NH{sub 3}). With the help of OES, the rotational temperature of the screen plasma could be determined.

  9. Fourier-transform infrared spectroscopy for rapid screening and live-cell monitoring: application to nanotoxicology

    Energy Technology Data Exchange (ETDEWEB)

    Sundaram, S. K.; Sacksteder, Colette A.; Weber, T. J.; Riley, Brian J.; Addleman, Raymond S.; Harrer, Bruce J.; Peterman, John W.

    2013-01-01

    A significant challenge to realize the full potential of nanotechnology for therapeutic and diagnostic applications is to understand and evaluate how live-cells interact with an external stimulus, e.g., a nanosized particle (NSP), and the toxicity and broad risk associated with these stimuli. NSPs are increasingly used in medicine with largely undetermined hazards in complex cell dynamics and environments. It is difficult to capture the complexity and dynamics of these interactions by following an omics-based approach exclusively, which are expensive and time-consuming. Additionally, this approach needs destructive sampling methods. Live-cell attenuated total reflectance-Fourier transform infrared (ATR-FTIR) spectrometry is well suited to provide noninvasive approach to provide rapid screening of cellular responses to potentially toxic NSPs or any stimuli. Herein we review the technical basis of the approach, the instrument configuration and interface with the biological media, and various effects that impact the data, data analysis, and toxicity. Our preliminary results on live-cell monitoring show promise for rapid screening the NSPs.

  10. Plasma nitriding monitoring reactor: A model reactor for studying plasma nitriding processes using an active screen

    Science.gov (United States)

    Hamann, S.; Börner, K.; Burlacov, I.; Spies, H.-J.; Strämke, M.; Strämke, S.; Röpcke, J.

    2015-12-01

    A laboratory scale plasma nitriding monitoring reactor (PLANIMOR) has been designed to study the basics of active screen plasma nitriding (ASPN) processes. PLANIMOR consists of a tube reactor vessel, made of borosilicate glass, enabling optical emission spectroscopy (OES) and infrared absorption spectroscopy. The linear setup of the electrode system of the reactor has the advantages to apply the diagnostic approaches on each part of the plasma process, separately. Furthermore, possible changes of the electrical field and of the heat generation, as they could appear in down-scaled cylindrical ASPN reactors, are avoided. PLANIMOR has been used for the nitriding of steel samples, achieving similar results as in an industrial scale ASPN reactor. A compact spectrometer using an external cavity quantum cascade laser combined with an optical multi-pass cell has been applied for the detection of molecular reaction products. This allowed the determination of the concentrations of four stable molecular species (CH4, C2H2, HCN, and NH3). With the help of OES, the rotational temperature of the screen plasma could be determined.

  11. Monitoring screen use: a qualitative exploration of family strategies in Swiss homes.

    Science.gov (United States)

    Piguet, Claire; Barrense-Dias, Yara; Ramelet, Anne-Sylvie; Suris, Joan-Carles

    2017-07-14

    Background Digital technologies make family managing more complicated, as parents are worried about their children's well-being and want to protect them from excessive Internet use. Objective The objective of this study was to investigate both youths' and parents' views on strategies and rules set at home to regulate and monitor Internet use. Subjects Thirty-five adolescents (19 females), aged between 11 and 18 years, and 27 parents (17 mothers) from the French-speaking part of Switzerland participated in different focus groups. Methods Using a qualitative approach, results were analyzed using the grounded theory. Results Eight different mediation strategies emerged. One relevant finding is that rules regarding problematic content were never mentioned, while rules about screen time and location of use were numerous. This might indicate that parents are more worried about the time spent in front of the screen than about the actual activities their children engage in. Conclusions It could be recommended to parents to keep striving for an environment contributing to open discussion and exchange on Internet use, even if their digital literacy is lower than their youngsters' are.

  12. Plasma nitriding monitoring reactor: A model reactor for studying plasma nitriding processes using an active screen.

    Science.gov (United States)

    Hamann, S; Börner, K; Burlacov, I; Spies, H-J; Strämke, M; Strämke, S; Röpcke, J

    2015-12-01

    A laboratory scale plasma nitriding monitoring reactor (PLANIMOR) has been designed to study the basics of active screen plasma nitriding (ASPN) processes. PLANIMOR consists of a tube reactor vessel, made of borosilicate glass, enabling optical emission spectroscopy (OES) and infrared absorption spectroscopy. The linear setup of the electrode system of the reactor has the advantages to apply the diagnostic approaches on each part of the plasma process, separately. Furthermore, possible changes of the electrical field and of the heat generation, as they could appear in down-scaled cylindrical ASPN reactors, are avoided. PLANIMOR has been used for the nitriding of steel samples, achieving similar results as in an industrial scale ASPN reactor. A compact spectrometer using an external cavity quantum cascade laser combined with an optical multi-pass cell has been applied for the detection of molecular reaction products. This allowed the determination of the concentrations of four stable molecular species (CH4, C2H2, HCN, and NH3). With the help of OES, the rotational temperature of the screen plasma could be determined.

  13. Field validation of radon monitoring as a screening methodology for NAPL-contaminated sites

    Energy Technology Data Exchange (ETDEWEB)

    Garcia-Gonzalez, J.E.; Ortega, M.F.; Chacon, E.; Mazadiego, L.F. [Grupo de Geoquimica Ambiental, Universidad Politecnica de Madrid, E.T.S. Ingenieros de Minas, Alenza 4, 28003 Madrid (Spain); Miguel, E. de [Grupo de Geoquimica Ambiental, Universidad Politecnica de Madrid, E.T.S. Ingenieros de Minas, Alenza 4, 28003 Madrid (Spain)], E-mail: eduardo.demiguel@upm.es

    2008-09-15

    Screening methodologies aim at improving knowledge about subsurface contamination processes before expensive intrusive operations, i.e. drilling and core-sampling, well installation and development, sampling of groundwater and free-phase product, are implemented. Blind field tests carried out at a hydrocarbon storage and distribution center in NE Spain suggest that Rn monitoring can be effectively used to locate the boundaries of subsurface accumulations of NAPLs. Sixty seven measurements of Rn in soil air were performed with a SARAD RTM 2100 current-ionization alpha-particle spectrometer following a 10 m square grid. Reductions of {sup 222}Rn concentration above a pool of LNAPL due to the preferential partition of Rn into the organic phase were spatially analyzed and resolved to yield the surface contour of the NAPL source zone. This surface trace of the source zone agreed well with the extent and situation inferred from measurements of free-phase thickness taken at eight monitoring wells at the site. Moreover, the good repeatability (as measured by replicate measurements at the same sampling point) and spatial resolution of the technique suggest that the boundaries of the plume can be delineated at the sub-decametre level.

  14. Improved GNSS processing and screening for ZTD monitoring in national network

    Science.gov (United States)

    Stepniak, K.; Bock, O.

    2016-12-01

    Discontinuities in Zenith Total Delay (ZTD) series estimated from ground-based GNSS data are detrimental to climate monitoring applications. This study aims at improving the processing strategy to reprocess GNSS data from national networks. A network of 136 GNSS stations (including 32 stations from the EUREF Permanent Network and 104 stations from ASG-EUPOS network in Poland) was reprocessed for year 2014 using Bernese GNSS Software v.5.2. The average distance between the stations is about 70 km. In order to investigate the influence of network design strategy, three variants of processing were carried out and analyzed: 1) using network design strategy which works quite well for coordinates; 2) the standard "obs-max" strategy recommended for Bernese software; 3) a newly developed baselines design strategy optimized for ZTD estimation. The study shows that the network design has a strong impact on the quality and continuity of ZTD estimates. In case of sub-daily gaps in the measurements at reference stations, small clusters of stations can be disconnected from the main network in the first network strategy. This has little impact on coordinates, but offsets of a few centimeters in ZTD estimates and spikes in their formal errors can appear at all stations of the disconnected cluster. It is also responsible for significant discontinuities in the estimated ZTD series. This problem is observed also with "obs-max" strategy. The new network design strategy proposed here allows to avoid this problem. The reprocessed ZTD time series are much more continuous and homogeneous in comparison to the standard strategies. However, even when an optimal processing procedure is used, some outliers in the ZTD series still remain (e.g. due to short data gaps). Therefore, a post-processing screening procedure consisting of the removal of the first and the last ZTD estimates around observations gaps, range and outlier check of ZTD and formal errors was applied to remove these bad values

  15. OPTIMAL WELL LOCATOR (OWL): A SCREENING TOOL FOR EVALUATING LOCATIONS OF MONITORING WELLS: USER'S GUIDE VERSION 1.2

    Science.gov (United States)

    The Optimal Well Locator ( OWL) program was designed and developed by USEPA to be a screening tool to evaluate and optimize the placement of wells in long term monitoring networks at small sites. The first objective of the OWL program is to allow the user to visualize the change ...

  16. Teachers' Attitudes about Using Curriculum-Based Measurement in Reading (CBM-R) for Universal Screening and Progress Monitoring

    Science.gov (United States)

    Rowe, Sarah Stebbe; Witmer, Sara; Cook, Elizabeth; daCruz, Katelin

    2014-01-01

    Universal screening and progress monitoring are two essential components of the response-to-intervention (RTI) framework. Within RTI models, teachers are commonly expected to collect, score, and use much of the associated student performance data. One measure that is commonly used within RTI models is Curriculum-Based Measurement in Reading…

  17. Cell culture monitoring for drug screening and cancer research: a transparent, microfluidic, multi-sensor microsystem.

    Science.gov (United States)

    Weltin, Andreas; Slotwinski, Kinga; Kieninger, Jochen; Moser, Isabella; Jobst, Gerhard; Wego, Marcus; Ehret, Ralf; Urban, Gerald A

    2014-01-07

    We present a novel, multiparametric microphysiometry system for the dynamic online monitoring of human cancer cell metabolism. The optically transparent, modular, hybrid microsystem is based on a glass chip and combines a cell cultivation chamber, microfluidics and metabolic monitoring with fully integrated chemo- and biosensors. pH and oxygen are measured in the cell culture area, and biosensors for lactate and glucose are connected downstream by microfluidics. The wafer-level fabrication features thin-film platinum and iridium oxide microelectrodes on a glass chip, microfluidics in an epoxy resist, a hybrid assembly and an on-chip reference electrode. The reliable analytical performance of the sensors in cell culture medium was demonstrated. The pH sensors exhibit a long-term stable, linear response. The oxygen sensors show a linear behaviour, which is also observed for low oxygen concentrations. Glucose and lactate measurements show a linear, long-term stable, selective and reversible behaviour in the desired range. T98G human brain cancer cells were cultivated and cell culture metabolism was measured on-chip. Stop/flow cycles were applied and extracellular acidification, respiration, glucose consumption and lactate production were quantified. Long-term metabolic rates were determined and all parameters could be measured in the outlet channel. A placement downstream of the cell cultivation area for biosensors was realised. A highly effective medium exchange and undiluted sampling from the cell culture chamber with low flow rates (2 μl min(-1)) and low volumes (15 μl per cycle) were achieved. The drug screening application was demonstrated by detecting alteration and recovery effects of cellular metabolism induced by the addition of substances to the medium.

  18. A comparison of the sit-and-reach test and the back-saver sit-and-reach test in university students

    National Research Council Canada - National Science Library

    López-Miñarro, Pedro A; Andújar, Pilar Sáinz de Baranda; Rodrñguez-Garcña, Pedro L

    2009-01-01

    ...) between the sit-and-reach test (SR) and the back-saver sit-and-reach test (BS). Seventy-six men (mean age ± SD: 23.45 ± 3.96 years) and 67 women (mean age ± SD: 23.85 ± 5.36 years) were asked to perform three trials of SR, BS left...

  19. Effects of screen filter on visibility of alphanumeric presentation on CRT and LCD monitors.

    Science.gov (United States)

    Zunjic, Aleksandar; Ristic, Ljiljana; Milanovic, Dragan D

    2012-01-01

    In this paper, a research that deals with the problem of determining of the visibility of the alphanumeric presentation on CRT and LCD screens is presented, in conditions when the screen filters are used, and when they are not used. A methodology that can be used for determination of the visibility of alphanumeric symbols on VDT screens is presented. It is determined the existence of differences in visibility of alphanumeric presentations when screen filters are used, compared to conditions when they are not used. This difference was statistically significant, while the visibility of the presented alphanumeric symbols on CRT and LCD screens that use screen filters is lower than when they are not used. For this reason, the use of protective screen filter is recommended in circumstances where a very high level of glare exists, when the visual fatigue is common appearance and when a user performs a task that does not depend on the detection of stimuli whose RGB values are low.

  20. A Mobile Health Data Collection System for Remote Areas to Monitor Women Participating in a Cervical Cancer Screening Campaign.

    Science.gov (United States)

    Quercia, Kelly; Tran, Phuong Lien; Jinoro, Jéromine; Herniainasolo, Joséa Lea; Viviano, Manuela; Vassilakos, Pierre; Benski, Caroline; Petignat, Patrick

    2017-08-28

    Barriers to efficient cervical cancer screening in low- and medium-income countries include the lack of systematic monitoring of the participants' data. The aim of this study was to assess the feasibility of a mobile health (m-Health) data collection system to facilitate monitoring of women participating to cervical cancer screening campaign. Women aged 30-65 years, participating in a cervical cancer screening campaign in Ambanja, Madagascar, were invited to participate in the study. Cervical Cancer Prevention System, an m-Health application, allows the registration of clinical data, while women are undergoing cervical cancer screening. All data registered in the smartphone were transmitted onto a secure, Web-based platform through the use of an Internet connection. Healthcare providers had access to the central database and could use it for the follow-up visits. Quality of data was assessed by computing the percentage of key data missing. A total of 151 women were recruited in the study. Mean age of participants was 41.8 years. The percentage of missing data for the key variables was less than 0.02%, corresponding to one woman's medical history data, which was not sent to the central database. Technical problems, including transmission of photos, human papillomavirus test results, and pelvic examination data, have subsequently been solved through a system update. The quality of the data was satisfactory and allowed monitoring of cervical cancer screening data of participants. Larger studies evaluating the efficacy of the system for the women's follow-up are needed in order to confirm its efficiency on a long-term scale.

  1. Predicting reading outcomes in the classroom using a computer-based phonological awareness screening and monitoring assessment (Com-PASMA).

    Science.gov (United States)

    Carson, Karyn; Boustead, Therese; Gillon, Gail

    2014-12-01

    The screening and monitoring of phonological awareness (PA) in the classroom is of great importance to the early identification and prevention of reading disorder. This study investigated whether a time-efficient computer-based PA screening and monitoring assessment (Com-PASMA) could accurately predict end-of-year reading outcomes for 5-year-old children in the first year of schooling. A longitudinal design was employed where the Com-PASMA was used to measure the PA ability of 95 5-year-old children at the start, middle, and end of the first year of school. Of this group, 21 children presented with spoken language impairment. Reading outcomes were formally measured after 1 year of schooling. School-entry measures of PA using the Com-PASMA (p < .001), in conjunction with language ability (p = .004), accounted for 68.9% of the variance in end-of-year word decoding ability. Sensitivity and specificity calculations demonstrated that the Com-PASMA was 92% accurate at school-entry, and 94% accurate by the middle of the school year in predicting reading outcomes at 6-years of age. Results suggest that a time-efficient computer-based method of screening and monitoring PA can support the early identification of reading difficulties in the first year of schooling.

  2. Lisp Object State Saver (LOSS): A facility used to save partial schedules of the Hubble Space Telescope

    Science.gov (United States)

    Sponsler, Jeffrey L.

    1988-01-01

    Current research in the area of long term scheduling of the Hubble Space Telescope is being done using Common Lisp and Flavors on Lisp Machines. The planning tools manipulate memory-resident data structures which represent the many entities and relationships that represent planning states. The Lisp Object State Saver (LOSS), a general purpose utility, was constructed which allows one to take a snapshot of memory by storing a representation of the structures in a text file. This text file can later be loaded thus restoring the pre-existing and logically equivalent planning state. A LOSS template must be created for each datatype to be stored and a simple grammar governs the creation of such templates.

  3. Screening and monitoring of main diseases a modern strategy of health maintenance in personnel of radiation dangerous plants

    Energy Technology Data Exchange (ETDEWEB)

    Takhauov, R. M.; Karpov, A. B.; Kubat, I. I.; Maslyuk, A. I.; Semenova, Y. V.; Freidin, M. B.; Trivozhenko, A. B.; Litvinenko, T. M.

    2004-07-01

    Population health is greatly determined by social factors, mode of life, ecological situation, amount and quality of medical assistance. The analysis of reasons of health troubles increase in population should be done taking into account the above aspects. Main consideration should be given to the development of measures aimed at the highest possible decrease of technogenic and anthropogenic factors influence on a human. Thereupon a complex programme of main diseases screening and monitoring in the personnel of the Siberian Group of Chemical enterprises (SGCE) to be the biggest one among Russian atomic plants has been developed. The purpose of the present paper is to determine main diseases at the earliest stage, the decrease of death rate, as well as the complex estimation of technogenic factor influence on the personnel of radiation dangerous plants nand their offsprings. In this case a long-term effect of low doses seems to be the main risk factor. Taking into account the structure of death rate causes of the population of industrialized countries as well as the spectrum of stochastic effects of ionizing radiation, the screening of cardiac ischemia and arterial hypertension, localization of cancer and congenital malformations have been chosen as the program priorities. Algorithm of instrumental laboratory screening of a particular disease includes modern diagnostic tests. Groups ar risk are formed taking into account a complex of exogenous and endogenous risk factors (age, chronic diseases, bad habits, length of service at a radiation dangerous plant, dose loads, hereditary factors) and on the basis of the screening examination results. The information obtained is entered in the list of database of the Regional Medico dosimetric Register of the SGCE personnel and Seversk residents followed by analysis and monitoring of groups ar risk. (Author) 4 refs.

  4. Screening for Circulating Tumour Cells Allows Early Detection of Cancer and Monitoring of Treatment Effectiveness: An Observational Study

    Science.gov (United States)

    Ried, Karin; Eng, Peter; Sali, Avni

    2017-08-27

    Background: Circulating-Tumour-Cells (CTC) provide a blood biomarker for early carcinogenesis, cancer progression and treatment effectiveness. An increase in CTCs is associated with cancer progression, a CTC decrease with cancer containment or remission. Several technologies have been developed to identify CTC, including the validated Isolation-by-Size-of-Epithelial-Tumour (ISET, Rarecells) technology, combining blood filtration and microscopy using standard histo-pathological criteria. Methods: This observational study compared CTC count to cancer status and cancer risk, by monitoring treatment effectiveness in cancer patients and by screening for CTC in asymptomatic patients with risk factors, including family history of cancer. Results: Between Sept-2014 and Dec-2016 we undertook 600 CTC tests (542 patients), including 50% screening requests of patients without cancer diagnosis but with risk factors. CTC were detected in all cancer patients (n=277, 100%), and in half of the asymptomatic patients screened (50%, 132 out-of 265 patients). Follow-up tests including scans, scheduled within 1-10 months of positive CTC tests, found early cancerous lesions in 20% of screened patients. In 50% of male patients with CTC and normal PSA (prostate-specific-antigen) levels, PSMA-PET scans revealed increased uptake in the prostate, indicative of early prostate cancer. Other types of cancers detected by CTC screening and subsequent scans included early breast, ovarian, lung, or renal cancer. Patients with CTC were advised on integrative approaches including immune-stimulating and anti-carcinogenic nutritional therapies. CTC repeat tests were available in 10% of patients with detected CTC (40 outof 409 patients, n=98 CTC tests) to assess treatment effectiveness, suggesting nutritional therapies to be beneficial in reducing CTC count. Conclusions: CTC screening provided a highly sensitive biomarker for the early detection of cancer, with higher CTC counts being associated with

  5. Beyond White Blood Cell Monitoring : Screening in the Initial Phase of Clozapine Therapy

    NARCIS (Netherlands)

    Cohen, Dan; Bogers, Jan P. A. M.; van Dijk, Daniel; Bakker, Bert; Schulte, Peter F. J.

    2012-01-01

    Objective: Clozapine is the preferred option for treatment-resistant schizophrenia. However, since 1975, clozapine has been known to cause agranulocytosis. In the clozapine screening guidelines, white blood cell count is mandatory. In the past 20 years, after its reintroduction, 3 other serious side

  6. Holter monitoring for the screening of cardiac disease in diabetes mellitus: The non-invasive Holter monitoring observation of new cardiac events in diabetics study.

    Science.gov (United States)

    Nakao, Yoko M; Ueshima, Kenji; Nohara, Ryuji; Mizunuma, Yoshimi; Segawa, Ikuo; Tanaka-Mizuno, Sachiko; Yasuno, Shinji; Nakao, Kazuwa; Hiramori, Katsuhiko; Kihara, Yasuki

    2015-11-01

    We investigated the usefulness of Holter monitoring to detect cardiac disease and predict future cardiovascular risk in asymptomatic diabetic patients. This is a multi-centre, prospective study in 406 asymptomatic diabetic patients. They were categorized into three groups based on findings of Holter monitoring. A total of 377 met inclusion criteria and were classified as low (n = 172), moderate (n = 136) and high risk (n = 69). In total, 86 in moderate and 53 in high risk receive further evaluation. In total, 29 in moderate and 25 in high risk were diagnosed as cardiac disease and 12 required additional treatment, including coronary intervention. Over 1.8 years of mean follow-up, 11 (16.5 per 1000 person-years) experienced cardiovascular events. The cumulative incidence in moderate and high risk was higher than that in low risk (p = 0.029 and p = 0.014, respectively). Our study suggests that Holter monitoring may be a useful screening tool to detect cardiac disease and predict future cardiovascular risk in asymptomatic diabetic patients.

  7. 可变径钻杆防喷盒的研制与应用∗%Variable-Diameter Drill Pipe Mud Saver

    Institute of Scientific and Technical Information of China (English)

    王建斌; 张妍; 熊青山; 熊潇; 王振宇; 周启成

    2016-01-01

    钻井起钻卸单根过程中,钻井液从钻柱接头处喷溅而出,不仅威胁工作人员健康安全,而且污染平台设备,为此研制了可变径钻杆防喷盒。该防喷盒为圆筒开合式结构,通过控制钻柱接头钻井液喷溅压力来回收和循环钻井液。运用Solidworks绘制防喷盒模型,采用ANSYS 对其MC尼龙材料进行分析。在江汉油田焦页4-2HF井和31-1HF井的试验中,可变径钻杆防喷盒具备良好的承压能力,试验效果良好,共收集钻井液36�24 m3,比常规起钻至少节约3 h。设计的可变径钻杆防喷盒实用性强,符合现场以及HSE要求。%The overflows of drilling fluid from drill pipe joint during break out after tripping out not only create risks for the health and safety of staff, but also pollute the platform equipment, thus, the variable⁃diameter drill pipe mud saver has been developed�The mud saver adopts the cylinder well⁃formed structure, recycling and circu⁃lating the drilling fluids by controlling the spray pressure of mud at drill string joint�The model of mud saver is de⁃signed using software of Solidworks, and the applied MC nylon material is analyzed using ANSYS�Field applica⁃tions in Well Jiaoye 4-2HF and Jiaoye 31-1HF in Sinopec Jianghan Oilfield show that the mud saver has good pressure⁃bearing capacity, and it had collected 36�24 m3 mud in total and saved more than 3 hours in pulling out process�The mud saver has great practicability and could meet the required standards of the field application and HSE rules.

  8. Screen-printed sensor for batch and flow injection potentiometric chromium(VI) monitoring

    Energy Technology Data Exchange (ETDEWEB)

    Sanchez-Moreno, Raul A.; Gismera, M.J.; Sevilla, M.T.; Procopio, Jesus R. [Facultad de Ciencias, Universidad Autonoma de Madrid, Departamento de Quimica Analitica y Analisis Instrumental, Madrid (Spain)

    2010-05-15

    A disposable screen-printed electrode was designed and evaluated for direct detection of chromium(VI) in batch and flow analysis. The carbon screen-printed electrode was modified with a graphite-epoxy composite. The optimal graphite-epoxy matrix contains 37.5% graphite powder, 12.5% diphenylcarbohydrazide, a selective compound for chromium(VI), and 50% epoxy resin. The principal analytical parameters of the potentiometric response in batch and flow analysis were optimized and calculated. The screen-printed sensor exhibits a response time of 20 {+-} 1 s. In flow analysis, the analytical frequency of sampling is 70 injections per hour using 0.1 M NaNO{sub 3} solution at pH 3 as the carrier, a flow rate of 2.5 mL.min{sup -1}, and an injection sample volume of 0.50 mL. The sensor shows potentiometric responses that are very selective for chromium(VI) ions and optimal detection limits in both static mode (2.1 x 10{sup -7} M) and online analysis (9.4 x 10{sup -7} M). The disposable potentiometric sensor was employed to determine toxicity levels of chromium(VI) in mineral, tap, and river waters by flow-injection potentiometry and batch potentiometry. Chromium(VI) determination was also carried out with successful results in leachates from municipal solid waste landfills. (orig.)

  9. Functionalized Carbon Quantum Dots with Dopamine for Tyrosinase Activity Monitoring and Inhibitor Screening: In Vitro and Intracellular Investigation.

    Science.gov (United States)

    Chai, Lujing; Zhou, Jin; Feng, Hui; Tang, Cong; Huang, Yuanyuan; Qian, Zhaosheng

    2015-10-28

    Sensitive assay of tyrosinase (TYR) activity is in urgent demand for both fundamental research and practical application, but the exploration of functional materials with good biocompatibility for its activity evaluation at the intracellular level is still challenging until now. In this work, we develop a convenient and real-time assay with high sensitivity for TYR activity/level monitoring and its inhibitor screening based on biocompatible dopamine functionalized carbon quantum dots (Dopa-CQDs). Dopamine with redox property was functionalized on the surface of carbon quantum dots to construct a Dopa-CQDs conjugate with strong bluish green fluorescence. When the dopamine moiety in Dopa-CQDs conjugate was oxidized to a dopaquinone derivative under specific catalysis of TYR, an intraparticle photoinduced electron transfer (PET) process between CQDs and dopaquinone moiety took place, and then the fluorescence of the conjugate could be quenched simultaneously. Quantitative evaluation of TYR activity was established in terms of the relationship between fluorescence quenching efficiency and TYR activity. The assay covered a broad linear range of up to 800 U/L with a low detection limit of 7.0 U/L. Arbutin, a typical inhibitor of TYR, was chosen as an example to assess its function of inhibitor screening, and positive results were observed that fluorescence quenching extent of the probe was reduced in the presence of arbutin. It is also demonstrated that Dopa-CQD conjugate possesses excellent biocompatibility, and can sensitively monitor intracellular tyrosinase level in melanoma cells and intracellular pH changes in living cells, which provides great potential in application of TYR/pH-associated disease monitoring and medical diagnostics.

  10. US EPA OPTIMAL WELL LOCATOR (OWL): A SCREENING TOOL FOR EVALUATING LOCATIONS OF MONITORING WELLS

    Science.gov (United States)

    The Optimal Well Locator (OWL): uses linear regression to fit a plane to the elevation of the water table in monitoring wells in each round of sampling. The slope of the plane fit to the water table is used to predict the direction and gradient of ground water flow. Along with ...

  11. Validity and reliability of the Back-Saver Sit and Reach in girls aged 7-8 years.

    Directory of Open Access Journals (Sweden)

    Milena Boneth-Collante

    2015-12-01

    Full Text Available Background: The back saver sit and reach (BSSR test is probably the most frequently quantitative tool used to estimate hamstring flexibility in the school and physical-sporting field due to its simplicity and quickly implementation. However, there is limited scientific evidence to justify its use in colombian girls. Objective: To assess the validity and intra-rater reliability of the BSSR in girls of a school from Bucaramanga. Mathodology: A study of evaluation of diagnostic technology was done in 64 girls (7-8 years, selected by convenience. BSSR test and straight leg raising test (SLRT were conducted on two consecutive occasions by the same researchers. It was calculed the Pearson (r or intraclass (ICC correlation coefficient with their respective confidence intervals (95% CI 95%. Results: The global validity was good (r=0.61 (95% CI 0.43-0.75 – r=0.66 (95% CI 0.49-0.78, while intra-rater reliability was very good in the left lower limb [ICC= 0.90 (95% CI 0.67 to 0.96] and right lower limb [ICC = 0.88 (95% CI 0.63 to 0.95]. Conclusion: BSSR test has good reliability and validity for assessing lower limb flexibility in girls aged 7 to 8 years.

  12. A high throughput screen for RGS proteins using steady state monitoring of free phosphate formation.

    Directory of Open Access Journals (Sweden)

    C Aaron Monroy

    Full Text Available G-protein coupled receptors are a diverse group that are the target of over 50% of marketed drugs. Activation of these receptors results in the exchange of bound GDP for GTP in the Gα subunit of the heterotrimeric G-protein. The Gα subunit dissociates from the β/γ subunits and both proceed to affect downstream signaling targets. The signal terminates by the hydrolysis of GTP to GDP and is temporally regulated by Regulators of G-protein Signaling (RGS proteins that act as GTPase Activating Proteins (GAPs. This makes RGS proteins potentially desirable targets for "tuning" the effects of current therapies as well as developing novel pharmacotherapies. Current methods for evaluating RGS activity depend on laborious and/or expensive techniques. In this study we developed a simple and inexpensive assay for the steady state analysis of RGS protein GAP activity, using RGS4, RGS8 and RGS17 as models. Additionally, we report the use of RGS4 as a model for high throughput assay development. After initial setup, this assay can be conducted in a highly parallel fashion with a read time of less than 8 minutes for a 1536-well plate. The assay exhibited a robust Z-factor of 0.6 in a 1536-well plate. We conducted a pilot screen for inhibitors using a small, 2320 compound library. From this screen, 13 compounds were identified as compounds for further analysis. The successful development of this assay for high-throughput screening provides a low cost, high speed, simple method for assessing RGS protein activity.

  13. Toward an objective indexing system for ADHD-screening using children's activity monitoring.

    Science.gov (United States)

    Kam, Hye Jin; Choi, Jong Pil; Park, Rae Woong

    2008-11-06

    Signs of ADHD are discernible in specific situations, and usually assessed according to subjective impressions. We performed a preliminary comparative study from children's activity at a natural classroom environment with 3-axis accelerator for a feasible objective index. From a total of 157 children (7-9 yrs) and clinically diagnosed 24 children out of them, variances in 1-min epoch mean activity had shown significant differences among the subgroups: (1) ADHD=.0194, Other Diseases=.0080, Normal=.0009; (2) ADHD=.0194, non-ADHD=.0057(p1.6G) features among subgroups with the same order (pindexing system for screening ADHD patients.

  14. Screening and monitoring zearalenone-producing Fusarium species by PCR and zearalenone by monoclonal antibodies in feed from China.

    Science.gov (United States)

    Pei, Shi-Chun; Zhen, Yu-Ping; Gao, Jian-Wei; Lee, Won-Jong; Zhang, Hong-Fu; Ji, Cheng; Zhang, Xuan-Zhe; Chen, Cong

    2014-01-01

    Screening of zearalenone (ZEN)-producing species and monitoring of ZEN in feed were performed by using anti-zearalenone monoclonal antibodies. ELISA recoveries of ZEN from corn distillers dried grains with solubles (DDGS) feed, corn feed, rice bran, soybean meal, wheat bran and rapeseed dregs were between 78.6% and 88.6%. ZEN recovery from culture media was 96.3% at the spiked level of 500 µg/kg. Eighty-three samples of DDGS feed, corn feed and other fee ingredients were collected from 11 provinces of China and analysed for ZEN. Average ZEN levels were 563.4 µg/kg for DDGS feed, 393.1 µg/kg for corn feed and 65.7 µg/kg for other feed ingredients. Eighteen Fusarium species such as Fusarium graminearum which could produce ZEN were isolated from corn feed and other feed ingredients.

  15. Automated high-performance cIMT measurement techniques using patented AtheroEdge™: a screening and home monitoring system.

    Science.gov (United States)

    Molinari, Filippo; Meiburger, Kristen M; Suri, Jasjit

    2011-01-01

    The evaluation of the carotid artery wall is fundamental for the assessment of cardiovascular risk. This paper presents the general architecture of an automatic strategy, which segments the lumen-intima and media-adventitia borders, classified under a class of Patented AtheroEdge™ systems (Global Biomedical Technologies, Inc, CA, USA). Guidelines to produce accurate and repeatable measurements of the intima-media thickness are provided and the problem of the different distance metrics one can adopt is confronted. We compared the results of a completely automatic algorithm that we developed with those of a semi-automatic algorithm, and showed final segmentation results for both techniques. The overall rationale is to provide user-independent high-performance techniques suitable for screening and remote monitoring.

  16. Environmental monitoring and assessment of antibacterial metabolite producing actinobacteria screened from marine sediments in south coastal regions of Karnataka, India.

    Science.gov (United States)

    Skariyachan, Sinosh; Garka, Shruthi; Puttaswamy, Sushmitha; Shanbhogue, Shobitha; Devaraju, Raksha; Narayanappa, Rajeswari

    2017-06-01

    Assessment of the therapeutic potential of secondary metabolite producing microorganisms from the marine coastal areas imparts scope and application in the field of environmental monitoring. The present study aims to screen metabolites with antibacterial potential from actionbacteria associated with marine sediments collected from south coastal regions of Karnataka, India. The actinobacteria were isolated and characterized from marine sediments by standard protocol. The metabolites were extracted, and antibacterial potential was analyzed against eight hospital associated bacteria. The selected metabolites were partially characterized by proximate analysis, SDS-PAGE, and FTIR-spectroscopy. The antibiogram of the test clinical isolates revealed that they were emerged as multidrug-resistant strains (P ≤ 0.05). Among six actinobacteria (IS1-1S6) screened, 100 μl(-1) metabolite from IS1 showed significant antibacterial activities against all the clinical isolates except Pseudomonas aeruginosa. IS2 demonstrated antimicrobial potential towards Proteus mirabilis, Streptococcus pyogenes, and Escherichia coli. The metabolite from IS3 showed activity against Strep. pyogenes and E. coli. The metabolites from IS4, IS5, and IS6 exhibited antimicrobial activities against Ps. aeruginosa (P ≤ 0.05). The two metabolites that depicted highest antibacterial activities against the test strains were suggested to be antimicrobial peptides with low molecular weight. These isolates were characterized and designated as Streptomyces sp. strain mangaluru01 and Streptomyces sp. mangaloreK01 by 16S ribosomal DNA (rDNA) sequencing. This study suggests that south coastal regions of Karnataka, India, are one of the richest sources of antibacterial metabolites producing actinobacteria and monitoring of these regions for therapeutic intervention plays profound role in healthcare management.

  17. Ecotoxicity monitoring and bioindicator screening of oil-contaminated soil during bioremediation.

    Science.gov (United States)

    Shen, Weihang; Zhu, Nengwu; Cui, Jiaying; Wang, Huajin; Dang, Zhi; Wu, Pingxiao; Luo, Yidan; Shi, Chaohong

    2016-02-01

    A series of toxicity bioassays was conducted to monitor the ecotoxicity of soils in the different phases of bioremediation. Artificially oil-contaminated soil was inoculated with a petroleum hydrocarbon-degrading bacterial consortium containing Burkholderia cepacia GS3C, Sphingomonas GY2B and Pandoraea pnomenusa GP3B strains adapted to crude oil. Soil ecotoxicity in different phases of bioremediation was examined by monitoring total petroleum hydrocarbons, soil enzyme activities, phytotoxicity (inhibition of seed germination and plant growth), malonaldehyde content, superoxide dismutase activity and bacterial luminescence. Although the total petroleum hydrocarbon (TPH) concentration in soil was reduced by 64.4%, forty days after bioremediation, the phytotoxicity and Photobacterium phosphoreum ecotoxicity test results indicated an initial increase in ecotoxicity, suggesting the formation of intermediate metabolites characterized by high toxicity and low bioavailability during bioremediation. The ecotoxicity values are a more valid indicator for evaluating the effectiveness of bioremediation techniques compared with only using the total petroleum hydrocarbon concentrations. Among all of the potential indicators that could be used to evaluate the effectiveness of bioremediation techniques, soil enzyme activities, phytotoxicity (inhibition of plant height, shoot weight and root fresh weight), malonaldehyde content, superoxide dismutase activity and luminescence of P. phosphoreum were the most sensitive.

  18. Non-target screening analyses of organic contaminants in river systems as a base for monitoring measures

    Science.gov (United States)

    Schwarzbauer, J.

    2009-04-01

    Organic contaminants discharged to the aquatic environment exhibit a high diversity with respect to their molecular structures and the resulting physico-chemical properties. The chemical analysis of anthropogenic contamination in river systems is still an important feature, especially with respect to (i) the identification and structure elucidation of novel contaminants, (ii) to the characterisation of their environmental behaviour and (iii) to their risk for natural systems. A huge proportion of riverine contamination is caused by low-molecular weight organic compounds, like pesticides plasticizers, pharmaceuticals, personal care products, technical additives etc. Some of them, like PCB or PAH have already been investigated thoroughly and, consequently, their behaviour in aqueous systems is very well described. Although analyses on organic substances in river water traditionally focused on selected pollutants, in particular on common priority pollutants which are monitored routinely, the occurrence of further contaminants, e.g. pharmaceuticals, personal care products or chelating agents has received increasing attention within the last decade. Accompanied, screening analyses revealing an enormous diversity of low-molecular weight organic contaminants in waste water effluents and river water become more and more noticed. Since many of these substances have been rarely noticed so far, it will be an important task for the future to study their occurrence and fate in natural environments. Further on, it should be a main issue of environmental studies to provide a comprehensive view on the state of pollution of river water, in particular with respect to lipophilic low molecular weight organic contaminants. However, such non-target-screening analyses has been performed only rarely in the past. Hence, we applied extended non-target screening analyses on longitudinal sections of the rivers Rhine, Rur and Lippe (Germany) on the base of GC/MS analyses. The investigations

  19. Monitoring and Varietal Screening Cucurbit Fruit Fly, Bactrocera cucurbitae Coquillett (Diptera: Tephritidae on Cucumber in Bhaktapur and Kathmandu, Nepal

    Directory of Open Access Journals (Sweden)

    Ranju Maharjan

    2015-12-01

    Full Text Available Monitoring of cucurbit fruit fly by using four different types of traps was conducted in Sipadole VDC of Bhaktapur district during 2012 to observe the population dynamics. Three different types of fruit flies were recorded, in which the number of B. cucurbitae dominated to other species. Only B. cucurbitae damaged the cucumber, which was trapped 92.68%, 87.05%, 90.61%, and 69.38% in cue-lure, banana pulp bait, sticky traps and fly catcher, respectively. The highest number of fruit flies (167.5 male fruit flies/3traps was recorded in cue-lure trap during the first week of September, which coincided with 85.45% RH and 21.67°C and 25.04°C minimum and maximum temperature, respectively. Positive relation of temperature, relative humidity and fruit fly catches was observed. Thus, cue-lure was the most effective traps for monitoring of fruit fly population. In varietal screening, among the six different varieties of cucumber, i.e. Kathmandu local, Kusle, Kamini, Malini, Kasinda and Mahyco Green Long, they were highly significant difference in yield. Kamini gave the highest marketable fruit 26.66 mt/ha yield and the lowest by Kusle (5.05 mt/ha. All the varieties were affected by cucurbit fruit fly. The highest number of unmarketable fruit set was observed in Kamini (22.29 fruits/plant.

  20. Screening and Monitoring Coeliac Disease: Multicentre Trial of a New Serum Antibody Test Kit

    Directory of Open Access Journals (Sweden)

    Peter L. Devine

    1994-01-01

    average interassay CV was 6.4% for IgA and 4.3% for IgG (n=3. By defining a positive te st as both IgA and IgG elevated, a sensitivity of 93% in untreated coeliacs (n=75 was observed. The corresponding specificities in healthy adults (n=130 and healthy children (n=77 were >99% and 100% respectively, while in patients with other gastrointestinal disorders (disease controls the specificity was 94% (n=129. The test was also useful in monitoring patients, with anti-gliadin IgA and IgG falling for up to a year after commencing a gluten-free diet (GFD (12 adults. In some patients however, antibody levels did not reach the normal cutpoint after many months on a GFD, which may reflect the patients ' poor adherence to their gluten free diet. The test was superior to the Pharmacia anti-gliadin ELISA, and should be useful as an aid to the diagnosis of coeliac disease, as well as in the follow-up of treated patients.

  1. Teachers' Attitudes about Using Curriculum-Based Measurement in Reading (CBM-R) for Universal Screening and Progress Monitoring

    Science.gov (United States)

    Rowe, Sarah Stebbe; Witmer, Sara; Cook, Elizabeth; daCruz, Katelin

    2014-01-01

    Universal screening and progress monitoring are two essential components of the response-to-intervention (RTI) framework. Within RTI models, teachers are commonly expected to collect, score, and use much of the associated student performance data. One measure that is commonly used within RTI models is Curriculum-Based Measurement in Reading…

  2. Evaluation of mobile smartphones app as a screening tool for environmental noise monitoring.

    Science.gov (United States)

    Ibekwe, Titus S; Folorunsho, David O; Dahilo, Enoch A; Gbujie, Ibeneche O; Nwegbu, Maxwell M; Nwaorgu, Onyekwere G

    2016-01-01

    Noise is a global occupational and environmental health hazard with considerable social and physiological impact and, therefore, there is a need for regular measurements to boost monitoring and regulations of environmental noise levels in our communities. This necessitates a readily available, inexpensive, and easy to use noise measuring device. We aimed to test the sensitivity and validity of mobile "smart" phones for this purpose. This was a comparative analysis of a cross sectional study done between January 2014 and February 2015. Noise levels were measured simultaneously at different locations within Abuja Nigeria at day and night hours in real time environments. A sound level meter (SLM) (Extech407730 Digital Soundmeter, serial no.: 2310135, calibration no: 91037) and three smartphones (Samsung Galaxy note3, Nokia S, and Techno Phantom Z running on Android "Apps" Androidboy1) were used. Statistical calculations were done with Pearson correlation, T-test and Consistency within American National Standards Institute acceptable standard errors. Noise level readings for both daytime and night with the SLM and the mobile phones showed equivalent values. All noise level meters measured were Smartphone instruments was 3db, noted in two locations. Readings in dBA showed strong correlation (r = 0.9) within acceptable error limits for Type 2 SLM devices and no significant difference in the values (p = 0.12 & 0.58) for both day and night. Sensitivity of the instrument yielded 92.9%. The androidboy1 "app" performance in this study showed a good correlation and comparative high sensitivity to the Standard SLM (type 2 SLM device). However there is the need for further studies.

  3. A rapid screening method to monitor expression of various recombinant proteins from prokaryotic and eukaryotic expression systems using MALDI-TOF mass spectrometry

    DEFF Research Database (Denmark)

    Jebanathirajah, J.A.; Andersen, S.; Blagoev, B.;

    2002-01-01

    Rapid methods using matrix-assisted laser desorption ionization-time-of-flight mass spectrometry to monitor recombinant protein expression from various prokaryotic and eukaryotic cell culture systems were devised. Intracellular as well as secreted proteins from both induced and constitutive...... expression systems were measured and monitored from whole cells and growth media, thus providing an alternative to time-consuming traditional methods for screening and monitoring of protein expression. The methods described here involve minimal processing of samples and are therefore relevant to high...

  4. Label-free cardiac contractility monitoring for drug screening applications based on compact high-speed lens-free imaging

    Science.gov (United States)

    Pauwelyn, Thomas; Reumers, Veerle; Vanmeerbeeck, Geert; Stahl, Richard; Janssens, Stefan; Lagae, Liesbet; Braeken, Dries; Lambrechts, Andy

    2015-03-01

    Cardiotoxicity is the major cause of drug withdrawal from the market, despite rigorous toxicity testing during the drug development process. Existing safety screening techniques, some of which are based on simplified cellular assays, others on electrical (impedance) or optical (fluorescent microscopy) measurements, are either too limited in throughput or offer too poor predictability of toxicity to be applied on large numbers of compounds in the early stage of drug development. We present a compact optical system for direct (label-free) monitoring of fast cellular movements that enable low cost and high throughput drug screening. Our system is based on a high-speed lens-free in-line holographic microscope. When compared to a conventional microscope, the system can combine adequate imaging resolution (5.5 μm pixel pitch) with a large field-of-view (63.4 mm2) and high speed (170 fps) to capture physical cell motion in real-time. This combination enables registration of cardiac contractility parameters such as cell contraction frequency, total duration, and rate and duration of both contraction and relaxation. The system also quantifies conduction velocity, which is challenging in existing techniques. Additionally, to complement the imaging hardware we have developed image processing software that extracts all the contractility parameters directly from the raw interference images. The system was tested with varying concentration of the drug verapamil and at 100 nM, showed a decrease in: contraction frequency (-23.3% +/- 13%), total duration (-21% +/- 5%), contraction duration (-19% +/- 6%) and relaxation duration (-21% +/- 8%). Moreover, contraction displacement ceased at higher concentrations.

  5. A multiparametric automatic method to monitor long-term reproducibility in digital mammography: results from a regional screening programme.

    Science.gov (United States)

    Gennaro, G; Ballaminut, A; Contento, G

    2017-09-01

    This study aims to illustrate a multiparametric automatic method for monitoring long-term reproducibility of digital mammography systems, and its application on a large scale. Twenty-five digital mammography systems employed within a regional screening programme were controlled weekly using the same type of phantom, whose images were analysed by an automatic software tool. To assess system reproducibility levels, 15 image quality indices (IQIs) were extracted and compared with the corresponding indices previously determined by a baseline procedure. The coefficients of variation (COVs) of the IQIs were used to assess the overall variability. A total of 2553 phantom images were collected from the 25 digital mammography systems from March 2013 to December 2014. Most of the systems showed excellent image quality reproducibility over the surveillance interval, with mean variability below 5%. Variability of each IQI was 5%, with the exception of one index associated with the smallest phantom objects (0.25 mm), which was below 10%. The method applied for reproducibility tests-multi-detail phantoms, cloud automatic software tool to measure multiple image quality indices and statistical process control-was proven to be effective and applicable on a large scale and to any type of digital mammography system. • Reproducibility of mammography image quality should be monitored by appropriate quality controls. • Use of automatic software tools allows image quality evaluation by multiple indices. • System reproducibility can be assessed comparing current index value with baseline data. • Overall system reproducibility of modern digital mammography systems is excellent. • The method proposed and applied is cost-effective and easily scalable.

  6. Community air monitoring for pesticides. Part 3: using health-based screening levels to evaluate results collected for a year.

    Science.gov (United States)

    Wofford, Pamela; Segawa, Randy; Schreider, Jay; Federighi, Veda; Neal, Rosemary; Brattesani, Madeline

    2014-03-01

    The CA Department of Pesticide Regulation (CDPR) and the CA Air Resources Board monitored 40 pesticides, including five degradation products, in Parlier, CA, to determine if its residents were exposed to any of these pesticides and, if so, in what amounts. They included 1,3-dichloropropene, acrolein, arsenic, azinphos-methyl, carbon disulfide, chlorpyrifos and its degradation product, chlorthalonil, copper, cypermethrin, diazinon and its degradation product, dichlorvos, dicofol, dimethoate and its degradation product, diuron, endosulfan and its degradation product, S-ethyl dipropylcarbamothioate (EPTC), formaldehyde, malathion and its degradation product, methyl isothiocyanate (MITC), methyl bromide, metolachlor, molinate, norflurazon, oryzalin, oxyfluorfen, permethrin, phosmet, propanil, propargite, simazine, SSS-tributylphosphorotrithioate, sulfur, thiobencarb, trifluralin, and xylene. Monitoring was conducted 3 days per week for a year. Twenty-three pesticides and degradation products were detected. Acrolein, arsenic, carbon disulfide, chlorpyrifos, copper, formaldehyde, methyl bromide, MITC, and sulfur were detected in more than half the samples. Since no regulatory ambient air standards exist for these pesticides, CDPR developed advisory, health-based non-cancer screening levels (SLs) to assess acute, subchronic, and chronic exposures. For carcinogenic pesticides, CDPR assessed risk using cancer potency values. Amongst non-carcinogenic agricultural use pesticides, only diazinon exceeded its SL. For carcinogens, 1,3-dichloropropene concentrations exceeded its cancer potency value. Based on these findings, CDPR has undertaken a more comprehensive evaluation of 1,3-dichloropropene, diazinon, and the closely related chlorpyrifos that was frequently detected. Four chemicals-acrolein, arsenic, carbon disulfide, and formaldehyde-sometimes used as pesticides were detected, although no pesticidal use was reported in the area during this study. Their presence was most

  7. Intergrating injury screening with measurement and monitoring: a conceptual approach using a patient global assessment of the body and limbs scale

    Directory of Open Access Journals (Sweden)

    P. Gabel

    2006-02-01

    Full Text Available Purpose: To  develop a conceptual model for patients withmusculoskeletal injuries that relates Injury Screening to Measurement and Monitoring (ISMAM. Screening scores would predict quantifiable outcomes on a proposed Global Assessment of Body And Limbs (GABAL composite scale.  The scale would define status as a percentage of pre-injury capacity using quantitative and qualitative self report outcome measures combined with work and life status data. Background: Screening questionnaires use psychosocial yellow flags and activity limitation to identify potential chronic patients. Outcome measures provide clinical evidence by establishing patient status and assessing intervening change.  Independently developed,definitive statistical links between these established concepts are yet to be determined. Description: The ISMAM components are integrated using a graph of time versus score on the GABAL-scale with initial screening predicting recovery time to a designated pre-injury percentage level.  Actual status would be assessed through initial then subsequent sequential measurements with GABAL-scale scores enabling trendline analysis to  verify if the rate of actual recovery coincides with that predicted by screening. Observations: Face and content validity are apparent because validated screening tools are available and the requiredcomponents for the GABAL-scale would be existing validated outcome measures and quantifiable data.Conclusions: This model should provide a practical method of integrating screening and global measurement thatfacilitates communication across agencies and professions.  A clinical research trial to validate the ISMAM concepthas been initiated.

  8. A fluorescence-based assay to monitor autopalmitoylation of zDHHC proteins applicable to high-throughput screening.

    Science.gov (United States)

    Hamel, Laura D; Deschenes, Robert J; Mitchell, David A

    2014-09-01

    Palmitoylation, the posttranslational thioester-linked modification of a 16-carbon saturated fatty acid onto the cysteine residue of a protein, has garnered considerable attention due to its implication in a multitude of disease states. The signature DHHC motif (Asp-His-His-Cys) identifies a family of protein acyltransferases (PATs) that catalyze the S-palmitoylation of target proteins via a two-step mechanism. In the first step, autopalmitoylation, palmitate is transferred from palmitoyl-CoA to the PAT, creating a palmitoyl:PAT intermediate and releasing reduced CoA. The palmitoyl moiety is then transferred to a protein substrate in the second step of the reaction. We have developed an in vitro, single-well, fluorescence-based enzyme assay that monitors the first step of the PAT reaction by coupling the production of reduced CoA to the reduction of NAD(+) using the α-ketoglutarate dehydrogenase complex. This assay is suitable for determining PAT kinetic parameters, elucidating lipid donor specificity and measuring PAT inhibition by 2-bromopalmitate. Finally, it can be used for high-throughput screening (HTS) campaigns for modulators of protein palmitoylation. Copyright © 2014 Elsevier Inc. All rights reserved.

  9. Multi-channel microfluidic biosensor platform applied for online monitoring and screening of biofilm formation and activity.

    Science.gov (United States)

    Bruchmann, Julia; Sachsenheimer, Kai; Rapp, Bastian E; Schwartz, Thomas

    2015-01-01

    Bacterial colonization of surfaces and interfaces has a major impact on various areas including biotechnology, medicine, food industries, and water technologies. In most of these areas biofilm development has a strong impact on hygiene situations, product quality, and process efficacies. In consequence, biofilm manipulation and prevention is a fundamental issue to avoid adverse impacts. For such scenario online, non-destructive biofilm monitoring systems become important in many technical and industrial applications. This study reports such a system in form of a microfluidic sensor platform based on the combination of electrical impedance spectroscopy and amperometric current measurement, which allows sensitive online measurement of biofilm formation and activity. A total number of 12 parallel fluidic channels enable real-time online screening of various biofilms formed by different Pseudomonas aeruginosa and Stenotrophomonas maltophilia strains and complex mixed population biofilms. Experiments using disinfectant and antibiofilm reagents demonstrate that the biofilm sensor is able to discriminate between inactivation/killing of bacteria and destabilization of biofilm structures. The impedance and amperometric sensor data demonstrated the high dynamics of biofilms as a consequence of distinct responses to chemical treatment strategies. Gene expression of flagellar and fimbrial genes of biofilms grown inside the microfluidic system supported the detected biofilm growth kinetics. Thus, the presented biosensor platform is a qualified tool for assessing biofilm formation in specific environments and for evaluating the effectiveness of antibiofilm treatment strategies.

  10. Diabetic Retinopathy Screening and Monitoring of Early Stage Disease in Australian General Practice: Tackling Preventable Blindness within a Chronic Care Model

    Directory of Open Access Journals (Sweden)

    Lisa Crossland

    2016-01-01

    Full Text Available Introduction. Diabetic retinopathy (DR is the leading cause of preventable blindness in Australia. Up to 50% of people with proliferative DR who do not receive timely treatment will become legally blind within five years. Innovative and accessible screening, involving a variety of primary care providers, will become increasingly important if patients with diabetes are to receive optimal eye care. Method. An open controlled trial design was used. Five intervention practices in urban, regional, and rural Australia partnered with ophthalmologists via telehealth undertook DR screening and monitoring of type 2 diabetes patients and were compared with control practices undertaking usual care 2011–2014. Results. Recorded screening rates were 100% across intervention practices, compared with 22–53% in control practices. 31/577 (5% of patients in the control practices were diagnosed with mild-moderate DR, of whom 9 (29% had appropriate follow-up recorded. This was compared with 39/447 (9% of patients in the intervention group, of whom 37 (95% had appropriate follow-up recorded. Discussion and Conclusion. General practice-based DR screening via Annual Cycle of Care arrangements is effective across differing practice locations. It offers improved recording of screening outcomes for Australians with type 2 diabetes and better follow-up of those with screen abnormalities.

  11. Opportunistic prostate-specific antigen screening in Italy: 6 years of monitoring from the Italian general practice database.

    Science.gov (United States)

    D'Ambrosio, Gaetano Giorgio; Campo, Salvatore; Cancian, Maurizio; Pecchioli, Serena; Mazzaglia, Giampiero

    2010-11-01

    The practice of prostate-specific antigen (PSA) screening has been increasing in Italy despite uncertain scientific evidence and contrary recommendations from most scientific societies. In 2002, a survey of PSA screening diffusion among general practices was performed, looking for screening frequency and age pattern of screened individuals. The objective of this study was to assess whether the features of PSA screening did change after 6 years in the same considered setting. Using the data obtained from 500 Italian general practitioners providing information to the Health Search/CSD Patient database, we selected, for the study purpose 351,091 male individuals. We assumed PSA prescriptions performed during 2005-2008 in individuals without prostate cancer, or benign prostate disease, or urological symptoms history to have a screening purpose. Screening frequency was analyzed in the overall series, by year and by patient's age. Exposure to PSA screening (at least on PSA test in the considered period) of males aged over 50 years raised from 31.4% (confidence interval 95% 31.08-31.70%) during 2002 to 46.4% (confidence interval 95% 46.19-46.68%) during 2008. The highest yearly exposure to PSA screening (55%) and the highest frequency of repeat testing was observed in the 70-79 age range. PSA screening practice has continued to increase in Italy and is often performed in elderly people without any scientific rationale.

  12. A novel high throughput assay for anthelmintic drug screening and resistance diagnosis by real-time monitoring of parasite motility.

    Directory of Open Access Journals (Sweden)

    Michael J Smout

    Full Text Available BACKGROUND: Helminth parasites cause untold morbidity and mortality to billions of people and livestock. Anthelmintic drugs are available but resistance is a problem in livestock parasites, and is a looming threat for human helminths. Testing the efficacy of available anthelmintic drugs and development of new drugs is hindered by the lack of objective high-throughput screening methods. Currently, drug effect is assessed by observing motility or development of parasites using laborious, subjective, low-throughput methods. METHODOLOGY/PRINCIPAL FINDINGS: Here we describe a novel application for a real-time cell monitoring device (xCELLigence that can simply and objectively assess anthelmintic effects by measuring parasite motility in real time in a fully automated high-throughput fashion. We quantitatively assessed motility and determined real time IC(50 values of different anthelmintic drugs against several developmental stages of major helminth pathogens of humans and livestock, including larval Haemonchus contortus and Strongyloides ratti, and adult hookworms and blood flukes. The assay enabled quantification of the onset of egg hatching in real time, and the impact of drugs on hatch rate, as well as discriminating between the effects of drugs on motility of drug-susceptible and -resistant isolates of H. contortus. CONCLUSIONS/SIGNIFICANCE: Our findings indicate that this technique will be suitable for discovery and development of new anthelmintic drugs as well as for detection of phenotypic resistance to existing drugs for the majority of helminths and other pathogens where motility is a measure of pathogen viability. The method is also amenable to use for other purposes where motility is assessed, such as gene silencing or antibody-mediated killing.

  13. Circulating cell-free microRNA as biomarkers for screening, diagnosis and monitoring of neurodegenerative diseases and other neurologic pathologies

    Directory of Open Access Journals (Sweden)

    Kira S Sheinerman

    2013-09-01

    Full Text Available Many neurodegenerative diseases, such as Alzheimer’s disease, Parkinson disease, vascular and frontotemporal dementias, as well as other chronic neurological pathologies, are characterized by slow development with a long asymptomatic period followed by a stage with mild clinical symptoms. As a consequence, these serious pathologies are diagnosed late in the course of a disease, when massive death of neurons has already occurred and effective therapeutic intervention is problematic. Thus, the development of screening tests capable of detecting neurodegenerative diseases during early, preferably asymptomatic, stages is a high unmet need. Since such tests are to be used for screening of large populations, they should be non-invasive and relatively inexpensive. Further, while subjects identified by screening tests can be further tested with more invasive and expensive methods, e.g. analysis of cerebrospinal fluid or imaging techniques, to be of practical utility screening tests should have high sensitivity and specificity. In this review, we discuss advantages and disadvantages of various approaches to developing screening tests based on analysis of circulating cell-free miRNA. Applications of circulating miRNA-based tests for diagnosis of acute and chronic brain pathologies, for research of normal brain aging, and for disease and treatment monitoring are also discussed.

  14. Development and Application of an External Intelligent Power Saver for Drinking Water Dispenser%一种外置式智能饮水机节电器的研制与应用

    Institute of Scientific and Technical Information of China (English)

    陈忠仁; 陈芳靖; 朱雁锋

    2012-01-01

    为克服已有的饮水机节电器不能有效避免"千滚水"的形成,以及节电效果不理想的缺点,研制了一种外置式智能饮水机节电器,采用单片机作为控制核心,设计了加热自动检测、水沸报警、实时时钟、工作模式指示等硬件电路,并给出了软件设计。所研制的节电器经试用,节电效果良好,值得推广使用。%Because the existing power savers for drinking dispensers cannot avoid the problem of heating water repeatedly and their energy-saving effect is not ideal,an external intelligent power saver is developed.For it,single-chip microcomputer is adopted as the control core,and automatic water heating testing circuit,water boiling alarm circuit,real-time clock circuit,and work mode indication circuit are designed.Meanwhile,the software design is also given.The trial application of the developed power saver shows that its effect of energy-saving is good and it is worth using widely.

  15. Impact of screening and monitoring of capillary blood glucose in the detection of hyperglycemia and hypoglycemia in non-critical inpatients

    Directory of Open Access Journals (Sweden)

    Rogerio Silicani Ribeiro

    2011-03-01

    Full Text Available Objective: To evaluate the impact of screening hyper and hypoglycemia measured by capillary glycemia and standard monitorization of  hyperglycemic patients hospitalized in regular care units of Hospital Israelita Albert Einstein. Methods: The capillary glycemia was  measured by the Precision PCx (Abbott glucosimeter, using the PrecisionWeb (Abbott software. The detection of hyper and hypoglycemia during the months of May/June were compared to those of March/April in 2009 and to the frequency of the diagnosis of diabetes in 2007. Rresults: There was an increase in the glycemia screening from 27.7 to 77.5% of hospitalized patients (p < 0.001, of hyperglycemia detection (from 9.3 to 12.2%; p < 0.001 and of hypoglycemia (from 1.5 to 3.3%; p < 0.001 during  the months of May/June  2009. According to this action 14 patients for each additional case of hyperglycemia and 26 cases for each case of hypoglycemia were identified. The detection of hyperglycemia was significantly higher (p < 0.001 than the frequency of registered diagnosis related do diabetes in the year of 2007. Cconclusions: the adoption of an institutional program of glycemia monitorization improves the detection of hyper and hypoglycemia and glycemia control in hospitalized patients in regular care units.

  16. Utility of ELISA screening for the monitoring of abstinence from illegal and legal drugs in hair and urine.

    Science.gov (United States)

    Agius, Ronald; Nadulski, Thomas

    2014-06-01

    Amphetamines, cannabinoids, cocaine, opiates, methadone, and benzodiazepines in authentic hair samples with drug concentrations around the medical and psychological assessment (MPA) guidelines cut-offs were screened by LUCIO-direct ELISA kits. Following confirmation of all positive and a significant number of negatively screened samples with gas chromatography-mass spectrometry (GC-MS) or liquid chromatography-tandem mass spectrometry (LC-MS/MS) methods accredited for forensic purposes. Receiver operating characteristics (ROC) were plotted and the area under the curve (AUC) and overall misclassification rate (OMR) were calculated and compared to those obtained for the same drug classes in urine. While fulfilling the validation criteria of the German forensic guidelines, for almost all screening tests in hair and urine the AUC were greater than 0.8, indicating good to excellent performance. Moreover the AUC calculated for the detection of drugs in hair did not differ significantly to the AUC calculated for the detection of the same drug classes in urine, thus showing a comparable screening performance to the well accepted, previously published application of the same ELISAs for the detection of drugs at unconventionally low cut-offs in urine. For the first time, the validation of the immunoassay tests for the complete 6-drug panel MPA profile in hair and urine using a large population of authentic hair and urine samples with drug concentrations around MPA cut-offs, lower than conventional clinical or workplace drug testing guidelines cut-offs as well as those suggested by the Society of hair testing (SoHT) is presented.

  17. Economics of place-based monitoring under the safe drinking water act, part I: spatial and temporal patterns of contaminants, and design of screening strategies.

    Science.gov (United States)

    Brands, Edwin; Rajagopal, R

    2008-08-01

    The goals of environmental legislation and associated regulations are to protect public health, natural resources, and ecosystems. In this context, monitoring programs should provide timely and relevant information so that the regulatory community can implement legislation in a cost-effective and efficient manner. The Safe Drinking Water Act (SDWA) of 1974 attempts to ensure that public water systems (PWSs) supply safe water to its consumers. As is the case with many other federal environmental statutes, SDWA monitoring has been implemented in relatively uniform fashion across the USA. In this three part series, spatial and temporal patterns in water quality data are utilized to develop, compare, and evaluate the economic performance of alternative place-based monitoring approaches to current monitoring practice. Under the Safe Drinking Water Act (SDWA), a common list of over 90 contaminants is analyzed nationwide using EPA-authorized laboratory procedures. National and state-level summaries of SDWA data have shown that not all contaminants occur in all places at all times. This hypothesis is confirmed and extended by showing that only a few (less than seven) contaminants are of concern in any one of 19 Iowa surface water systems studied. These systems collectively serve about 350,000 people and their sizes vary between 1,200 and 120,000. The distributions of contaminants found in these systems are positively skewed, with many non-detect measurements. A screening strategy to identify such contaminants in individual systems is presented. These findings have significant implications not only for the design of alternative monitoring programs, but also in multi-billion-dollar decisions that influence the course of future drinking water infrastructure, repair, and maintenance investments.

  18. U.S. EPA OPTIMAL WELL LOCATOR (OWL): A SCREENING TOOL FOR EVALUATING LOCATIONS OF MONITORING WELLS (ROCKY GAP, MD)

    Science.gov (United States)

    The Optimal Well Locator (OWL): uses linear regression to fit a plane to the elevation of the water table in monitoring wells in each round of sampling. The slope of the plane fit to the water table is used to predict the direction and gradient of ground water flow. Along with ...

  19. In-situ nanoelectrospray for high-throughput screening of enzymes and real-time monitoring of reactions.

    Science.gov (United States)

    Yang, Yuhan; Han, Feifei; Ouyang, Jin; Zhao, Yunling; Han, Juan; Na, Na

    2016-01-01

    The in-situ and high-throughput evaluation of enzymes and real-time monitoring of enzyme catalyzed reactions in liquid phase is quite significant in the catalysis industry. In-situ nanoelectrospray, the direct sampling and ionization method for mass spectrometry, has been applied for high-throughput evaluation of enzymes, as well as the on-line monitoring of reactions. Simply inserting a capillary into a liquid system with high-voltage applied, analytes in liquid reaction system can be directly ionized at the capillary tip with small volume consumption. With no sample pre-treatment or injection procedure, different analytes such as saccharides, amino acids, alkaloids, peptides and proteins can be rapidly and directly extracted from liquid phase and ionized at the capillary tip. Taking irreversible transesterification reaction of vinyl acetate and ethanol as an example, this technique has been used for the high-throughput evaluation of enzymes, fast optimizations, as well as real-time monitoring of reaction catalyzed by different enzymes. In addition, it is even softer than traditional electrospray ionization. The present method can also be used for the monitoring of other homogenous and heterogeneous reactions in liquid phases, which will show potentials in the catalysis industry.

  20. Pathogen Screening of Naturally Produced Yakima River Spring Chinook Smolts; Yakima/Klickitat Fisheries Project Monitoring and Evaluation, 2004-2005 Annual Report.

    Energy Technology Data Exchange (ETDEWEB)

    Thomas, Joan B. (Washington Department of Fish and Wildlife, Olympia, WA)

    2005-05-01

    In the spring of 2004 naturally produced smolts outmigrating from the Yakima River Basin were collected for the sixth year of pathogen screening. This component of the evaluation is to monitor whether introduction of hatchery produced smolts would impact the prevalence of specific pathogens in the naturally produced spring chinook smolts. Increases in prevalence of any of these pathogens could negatively impact the survival of these fish. Since 1999 the Cle Elum Hatchery has been releasing spring chinook salmon smolts into the upper Yakima River to increase natural production. In 1998 and 2000 through 2004 naturally produced smolts were collected for monitoring at the Chandler smolt collection facility on the lower Yakima River. Smolts were collected from mid to late outmigration, with a target of 200 fish each year. The pathogens monitored were infectious hematopoeitic necrosis virus, infectious pancreatic necrosis virus, viral hemorrhagic septicemia virus, Flavobacterium psychrophilum, Flavobacterium columnare, Aeromonas salmonicida, Yersinia ruckeri, Edwardsiella ictaluri, Renibacterium salmoninarum and Myxobolus cerebralis. Of these pathogens, only R. salmoninarum was detected in very low levels in the naturally produced smolts outmigrating in 2004. To date, only bacterial pathogens have been detected and prevalences have been low. There have been small variations each year and these changes are attributed to normal fluctuations in prevalence. All of the pathogens detected are widely distributed in Washington State.

  1. A double-risk monitoring and movement restriction policy for Ebola entry screening at airports in the United States.

    Science.gov (United States)

    Jacobson, Sheldon H; Yu, Ge; Jokela, Janet A

    2016-07-01

    This paper provides an alternative policy for Ebola entry screening at airports in the United States. This alternative policy considers a social contact tracing (SCT) risk level, in addition to the current health risk level used by the CDC. The performances of both policies are compared based on the scenarios that occur and the expected cost associated with implementing such policies. Sensitivity analysis is performed to identify conditions under which one policy dominates the other policy. This analysis takes into account that the alternative policy requires additional data collection, which is balanced by a more cost-effective allocation of resources.

  2. Organic-resistant screen-printed graphitic electrodes: Application to on-site monitoring of liquid fuels

    Energy Technology Data Exchange (ETDEWEB)

    Almeida, Eduardo S.; Silva, Luiz A.J.; Sousa, Raquel M.F.; Richter, Eduardo M. [Universidade Federal de Uberlândia, Universidade Federal de Uberlândia, Av. João Naves de Ávila, 2121, Uberlândia, MG, 38408100 (Brazil); Foster, Christopher W.; Banks, Craig E. [Manchester Metropolitan University, Faculty of Science and the Environment, School of Science and the Environment, Division of Chemistry and Environmental Science, Manchester, M1 5GD, England (United Kingdom); Munoz, Rodrigo A.A., E-mail: raamunoz@iqufu.ufu.br [Universidade Federal de Uberlândia, Universidade Federal de Uberlândia, Av. João Naves de Ávila, 2121, Uberlândia, MG, 38408100 (Brazil)

    2016-08-31

    This work presents the potential application of organic-resistant screen-printed graphitic electrodes (SPGEs) for fuel analysis. The required analysis of the antioxidant 2,6-di-tert-butylphenol (2,6-DTBP) in biodiesel and jet fuel is demonstrated as a proof-of-concept. The screen-printing of graphite, Ag/AgCl and insulator inks on a polyester substrate (250 μm thickness) resulted in SPGEs highly compatible with liquid fuels. SPGEs were placed on a batch-injection analysis (BIA) cell, which was filled with a hydroethanolic solution containing 99% v/v ethanol and 0.1 mol L{sup −1} HClO{sub 4} (electrolyte). An electronic micropipette was connected to the cell to perform injections (100 μL) of sample or standard solutions. Over 200 injections can be injected continuously without replacing electrolyte and SPGE strip. Amperometric detection (+1.1 V vs. Ag/AgCl) of 2,6-DTBP provided fast (around 8 s) and precise (RSD = 0.7%, n = 12) determinations using an external calibration curve. The method was applied for the analysis of biodiesel and aviation jet fuel samples and comparable results with liquid and gas chromatographic analyses, typically required for biodiesel and jet fuel samples, were obtained. Hence, these SPGE strips are completely compatible with organic samples and their combination with the BIA cell shows great promise for routine and portable analysis of fuels and other organic liquid samples without requiring sophisticated sample treatments. - Highlights: • Organic-resistant screen-printed graphitic electrodes (SPGE) for (bio)fuels. • Screen-printing of conductive and insulator inks on thin polyester substrate. • Continuous detection of antioxidants in electrolyte with 99% v/v ethanol. • SPGE coupled with batch-injection analysis allows over 200 injections (100 μL). • Similar results to GC and HPLC analyses of biodiesel and aviation jet fuels.

  3. Identification of Alternative Vapor Intrusion Pathways Using Controlled Pressure Testing, Soil Gas Monitoring, and Screening Model Calculations.

    Science.gov (United States)

    Guo, Yuanming; Holton, Chase; Luo, Hong; Dahlen, Paul; Gorder, Kyle; Dettenmaier, Erik; Johnson, Paul C

    2015-11-17

    Vapor intrusion (VI) pathway assessment and data interpretation have been guided by an historical conceptual model in which vapors originating from contaminated soil or groundwater diffuse upward through soil and are swept into a building by soil gas flow induced by building underpressurization. Recent studies reveal that alternative VI pathways involving neighborhood sewers, land drains, and other major underground piping can also be significant VI contributors, even to buildings beyond the delineated footprint of soil and groundwater contamination. This work illustrates how controlled-pressure-method testing (CPM), soil gas sampling, and screening-level emissions calculations can be used to identify significant alternative VI pathways that might go undetected by conventional sampling under natural conditions at some sites. The combined utility of these tools is shown through data collected at a long-term study house, where a significant alternative VI pathway was discovered and altered so that it could be manipulated to be on or off. Data collected during periods of natural and CPM conditions show that the alternative pathway was significant, but its presence was not identifiable under natural conditions; it was identified under CPM conditions when measured emission rates were 2 orders of magnitude greater than screening-model estimates and subfoundation vertical soil gas profiles changed and were no longer consistent with the conventional VI conceptual model.

  4. Touch Screen and PLC in Cement Tank Monitoring System of Drilling Ship%触摸屏和PLC在钻井船输灰监测系统中的应用

    Institute of Scientific and Technical Information of China (English)

    孔祥伟; 于祥春; 孔凡旭; 杜刚; 宫俭纯

    2011-01-01

    The touch screen and PLC application in the cement tank monitoring system of drilling ship was introduced , including its working principle, PLC hardware configuration, network configuration and main touch screen interfaces.%将PLC和触摸屏应用于钻井船输灰监测系统,对灰罐工作原理、PLC硬件配置、网络组态和触摸屏主要界面进行了介绍.

  5. Enzyme-Linked Electrochemical Detection of PCR-Amplified Nucleotide Sequences Using Disposable Screen-Printed Sensors. Applications in Gene Expression Monitoring

    Directory of Open Access Journals (Sweden)

    Miroslav Fojta

    2008-01-01

    Full Text Available Electrochemical enzyme-linked techniques for sequence-specific DNA sensingare presented. These techniques are based on attachment of streptavidin-alkalinephosphatase conjugate to biotin tags tethered to DNA immobilized at the surface ofdisposable screen-printed carbon electrodes (SPCE, followed by production andelectrochemical determination of an electroactive indicator, 1-naphthol. Via hybridizationof SPCE surface-confined target DNAs with end-biotinylated probes, highly specificdiscrimination between complementary and non-complementary nucleotide sequences wasachieved. The enzyme-linked DNA hybridization assay has been successfully applied inanalysis of PCR-amplified real genomic DNA sequences, as well as in monitoring of planttissue-specific gene expression. In addition, we present an alternative approach involvingsequence-specific incorporation of biotin-labeled nucleotides into DNA by primerextension. Introduction of multiple biotin tags per probe primer resulted in considerableenhancement of the signal intensity and improvement of the specificity of detection.

  6. Computerised decision support systems in order communication for diagnostic, screening or monitoring test ordering: systematic reviews of the effects and cost-effectiveness of systems.

    Science.gov (United States)

    Main, C; Moxham, T; Wyatt, J C; Kay, J; Anderson, R; Stein, K

    2010-10-01

    Order communication systems (OCS) are computer applications used to enter diagnostic and therapeutic patient care orders and to view test results. Many potential benefits of OCS have been identified including improvements in clinician ordering patterns, optimisation of clinical time, and aiding communication processes between clinicians and different departments. Many OCS now include computerised decision support systems (CDSS), which are information systems designed to improve clinical decision-making. CDSS match individual patient characteristics to a computerised knowledge base, and software algorithms generate patient-specific recommendations. To investigate which CDSS in OCS are in use within the UK and the impact of CDSS in OCS for diagnostic, screening or monitoring test ordering compared to OCS without CDSS. To determine what features of CDSS are associated with clinician or patient acceptance of CDSS in OCS and what is known about the cost-effectiveness of CDSS in diagnostic, screening or monitoring test OCS compared to OCS without CDSS. A generic search to identify potentially relevant studies for inclusion was conducted using MEDLINE, EMBASE, Cochrane Controlled Trials Register (CCTR), CINAHL (Cumulative Index to Nursing and Allied Health Literature), DARE (Database of Abstracts of Reviews of Effects), Health Technology Assessment (HTA) database, IEEE (Institute of Electrical and Electronic Engineers) Xplore digital library, NHS Economic Evaluation Database (NHS EED) and EconLit, searched between 1974 and 2009 with a total of 22,109 titles and abstracts screened for inclusion. CDSS for diagnostic, screening and monitoring test ordering OCS in use in the UK were identified through contact with the 24 manufacturers/suppliers currently contracted by the National Project for Information Technology (NpfIT) to provide either national or specialist decision support. A generic search to identify potentially relevant studies for inclusion in the review was

  7. Stable and sensitive flow-through monitoring of phenol using a carbon nanotube based screen printed biosensor

    Energy Technology Data Exchange (ETDEWEB)

    Alarcon, G; Guix, M; Ambrosi, A; Merkoci, A [Nanobioelectronics and Biosensors Group, Catalan Institute of Nanotechnology, Campus UAB, 08193 Bellaterra, Barcelona, Catalonia (Spain); Ramirez Silva, M T [Departamento de Quimica, Universidad Autonoma Metropolitana Iztapalapa, 09340 Mexico Distrito Federal (Mexico); Palomar Pardave, M E, E-mail: arben.merkoci.icn@uab.es [Departamento de Materiales, Universidad Autonoma Metropolitana, Azcapotzalco, 02200 Mexico Distrito Federal (Mexico)

    2010-06-18

    A stable and sensitive biosensor for phenol detection based on a screen printed electrode modified with tyrosinase, multiwall carbon nanotubes and glutaraldehyde is designed and applied in a flow injection analytical system. The proposed carbon nanotube matrix is easy to prepare and ensures a very good entrapment environment for the enzyme, being simpler and cheaper than other reported strategies. In addition, the proposed matrix allows for a very fast operation of the enzyme, that leads to a response time of 15 s. Several parameters such as the working potential, pH of the measuring solution, biosensor response time, detection limit, linear range of response and sensitivity are studied. The obtained detection limit for phenol was 0.14 x 10{sup -6} M. The biosensor keeps its activity during continuous FIA measurements at room temperature, showing a stable response (RSD 5%) within a two week working period at room temperature. The developed biosensor is being applied for phenol detection in seawater samples and seems to be a promising alternative for automatic control of seawater contamination. The developed detection system can be extended to other enzyme biosensors with interest for several other applications.

  8. Second Trimester Maternal Serum Screening

    Science.gov (United States)

    ... page: Was this page helpful? Also known as: AFP Maternal; Maternal Serum AFP; MSAFP; msAFP; Triple Screen; Triple Test; Quad Screen; ... Free Fetal DNA Were you looking instead for AFP tumor markers , used to help diagnose and monitor ...

  9. Conditioning out-of-date bank-stored red blood cells using a cell-saver auto-transfusion device: effects on numbers of red cells and quality of suspension fluid.

    Science.gov (United States)

    Read, M S; Coles, P; Pomeroy, M; Anderson, E; Aziz, M I

    2014-11-01

    We investigated the utility of a cell-saver device for processing out-of-date red blood cells, by washing twenty bags of red blood cells that had been stored for between 36 and 55 days. The volume of recovered cells, and the characteristics of the suspension fluid, were measured before and after treatment. The ratio of free haemoglobin to total haemoglobin was up to 0.02 before processing, and up to 0.011 afterwards, changing by between -0.013 and +0.003. This ratio met the current standard for free haemoglobin (less than 0.008 in more than 75% of samples), both before and after processing. Ninety-three percent of red blood cells survived the process. Potassium ion concentration fell from above 15 mmol.l(-1) in all cases, to a mean of 6.4 mmol.l(-1) (p red blood cells remained intact after conditioning using a cell-saver, and the process lowered concentrations of potentially toxic solutes in the fluid in which they were suspended.

  10. Content validity to support the use of a computer-based phonological awareness screening and monitoring assessment (Com-PASMA) in the classroom.

    Science.gov (United States)

    Carson, Karyn; Boustead, Therese; Gillon, Gail

    2015-01-01

    This study investigated the content validity of a computer-based phonological awareness (PA) screening and monitoring assessment (Com-PASMA) designed to evaluate school-entry PA abilities. Establishing content validity by confirming that test items suitably 'fit' and sample a spectrum of difficulty levels is critical for ensuring educators can deduce accurate information to comprehensively differentiate curricular reading instruction. Ninety-five children, inclusive of 21 children with spoken language impairment, participated in a 1-year longitudinal study whereby the Com-PASMA was administered at the start, middle and end of the school year. Estimates of content validity using Rasch Model analysis demonstrated that: (1) rhyme oddity and initial phoneme identity tasks were most appropriate at school-entry and sampled a spectrum of difficulty levels, (2) more challenging phoneme level tasks (e.g. final phoneme identity, phoneme blending, phoneme deletion and phoneme segmentation) became increasingly appropriate and differentiated between high- and low-ability students by the middle and end of the first year of school and (3) letter-knowledge tasks were appropriate but declined in their ability to differentiate student ability as the year progressed. Findings demonstrate that the Com-PASMA has sufficient content validity to measure and differentiate between the PA abilities of 5-year-old children on entry to school.

  11. Identification of radionuclides for the spectroscopic radiation portal monitor for pedestrian screening under a low signal-to-noise ratio condition

    Energy Technology Data Exchange (ETDEWEB)

    Min, Eungi [Department of IT Convergence, Korea University, Seoul (Korea, Republic of); School of Biomedical Engineering, Korea University, Seoul (Korea, Republic of); Ko, Mincheol [School of Biomedical Engineering, Korea University, Seoul (Korea, Republic of); Department of Bio-convergence Engineering, Korea University, Seoul (Korea, Republic of); Lee, Hakjae [School of Biomedical Engineering, Korea University, Seoul (Korea, Republic of); Research Institute of Health Science, Korea University, Seoul (Korea, Republic of); Kim, Yongkwon [NuCare Medical Systems, Incheon (Korea, Republic of); Research Institute of Health Science, Korea University, Seoul (Korea, Republic of); Joung, Jinhun [NuCare Medical Systems, Incheon (Korea, Republic of); Joo, Sung-Kwan [School of Electrical Engineering, Korea University, Seoul (Korea, Republic of); Lee, Kisung, E-mail: kisung@korea.ac.kr [School of Biomedical Engineering, Korea University, Seoul (Korea, Republic of); Department of Bio-convergence Engineering, Korea University, Seoul (Korea, Republic of); Department of Medical Devices, Korea University Guro Hospital, Seoul (Korea, Republic of)

    2014-09-11

    The spectroscopic radiation portal monitor (SPM) is widely used for homeland security. Many research groups are studying the radionuclide identification method which is one of the most important factors in the performance of the SPM using the large size of a thallium activated sodium iodide (NaI(Tl)) detector. In this study, we developed the radionuclide identification method for the SPM for pedestrian screening using a single NaI(Tl) detector that is small in size (2 in.), which is much smaller than those in the existing studies under the low signal-to-noise-ratio (SNR) condition. From the anomalous radionuclide spectrum, the noise component was effectively reduced by the wavelet decomposition and the proposed background subtraction method, and the signal component was enhanced by the principal component analysis. Finally, peak locations which have been determined by the peak search algorithm with a valley check method were compared with a pre-calibrated and constructed radionuclide database. To verify the radiation identification performance of the proposed method, experiments with various kinds of sources ({sup 137}Cs, {sup 133}Ba, {sup 22}Na, and {sup 57}Co) and different SNR values (from distances of 10–150 cm and for scan times of 1–5 s) were performed. Although the high-SNR condition was explored as well, most experiments were conducted under the low-SNR condition to verify the robustness and reproducibility of the proposed algorithm. The results showed that over 98.3% of the single radionuclide detection rate was achieved regardless of which radionuclides were used, up to 50 cm under the worst SNR condition (1 s of scan time) and up to 90 cm under the best SNR condition (5 s of scan time). Furthermore we achieved accurate identification of multiple radionuclides at 40 cm with only 1 s of scan time. The results show that the proposed algorithm is competitive with the commercial method and our radionuclide identification method can be successfully applied

  12. 电刀与血液回收机联用对髋关节置换术患者血一氧化碳水平的影响%Effects of electrocautery plus cell saver on the blood levels of carbon monoxide in hip arthroplasty

    Institute of Scientific and Technical Information of China (English)

    陈燕涛; 何清; 刘尚礼; Ivo Michiels

    2006-01-01

    .RESULTS: Totally 49 patients were involved in the analysis of results. ① General data: Forty-nine ASA Ⅰ -Ⅱ patients were enrolled in this study.There were 35 and 14 patients in the observed and control group, respectively, with 7 and 3 had a history of coronary heart diseases (heart function of class Ⅰ - Ⅱ ) correspondingly. There were no obvious differences in the sex, age, mean operative time and mean estimated blood loss between the two groups (P > 0.05). The vital signs were stable in all the patients. ② CO-Hb concentration: In the observed group, the CO-Hb concentration in systemic blood at 6 hours postoperatively was significantly increased as compared with the preoperative and postoperative ones [(2.2±0.54)%,(1.6±0.34)%, (1.7±0.19)%, P < 0.05]; the CO-Hb concentration in salvaged blood was (2.6±0.62)%, which was significantly higher than that in systemic blood preoperatively and postoperatively (P < 0.01). In the control group, the CO-Hb concentration in systemic blood at 6 hours postoperatively had no obvious differences as compared with the preoperative and postoperative ones (P > 0.05). ③ Postoperative conditions: In the observed group, sinus tachycardia and inferior myocardial ischemia were detected by ECG monitoring in 2 patients with pre-existing coronary heart disease,which complained of precardial discomfort at 4-6 hours postoperatively.Higher levels of CO-Hb were detected in salvaged blood before retransfusion (39% and 4.5%) and in systemic blood at 6 hours postoperatively(3.5% and 4.2%). No patient in the control group demonstrated symptoms of CO intoxication or cardiovascular compromise, also no abnormal changes were revealed by ECG monitoring.CONCLUSION: Retransfusion of salvaged blood in hip arthroplasty with simultaneous use of electrocautery and a cell saver system leads to a significant increase of systemic CO-Hb concentration, which can provoke the cardiovascular compromise. Therefore, it is suggested to measure CO-Hb level in

  13. Voice Savers for Music Teachers

    Science.gov (United States)

    Cookman, Starr

    2012-01-01

    Music teachers are in a class all their own when it comes to voice use. These elite vocal athletes require stamina, strength, and flexibility from their voices day in, day out for hours at a time. Voice rehabilitation clinics and research show that music education ranks high among the professionals most commonly affected by voice problems.…

  14. Screening for Atrial Fibrillation

    DEFF Research Database (Denmark)

    Freedman, Ben; Camm, A. John; Calkins, Hugh

    2017-01-01

    in September 2015 to promote discussion and research about AF screening as a strategy to reduce stroke and death and to provide advocacy for implementation of country-specific AF screening programs. During 2016, 60 expert members of AF-SCREEN, including physicians, nurses, allied health professionals, health...... economists, and patient advocates, were invited to prepare sections of a draft document. In August 2016, 51 members met in Rome to discuss the draft document and consider the key points arising from it using a Delphi process. These key points emphasize that screen-detected AF found at a single timepoint...... that guidelines require for AF diagnosis and would therefore be preferred as screening tools. Certain patient groups, such as those with recent embolic stroke of uncertain source (ESUS), require more intensive monitoring for AF. Settings for screening include various venues in both the community and the clinic...

  15. A spatio-temporal screening tool for outlier detection in long term / large scale air quality observation time series and monitoring networks

    Science.gov (United States)

    Kracht, Oliver; Reuter, Hannes I.; Gerboles, Michel

    2013-04-01

    We present a consolidated screening tool for the detection of outliers in air quality monitoring data, which considers both attribute values and spatio-temporal relationships. Furthermore, an application example of warnings on abnormal values in time series of PM10 datasets in AirBase is presented. Spatial or temporal outliers in air quality datasets represent stations or individual measurements which differ significantly from other recordings within their spatio-temporal neighbourhood. Such abnormal values can be identified as being extreme compared to their neighbours, even though they do not necessarily require to differ significantly from the statistical distribution of the entire population. The identification of such outliers can be of interest as the basis of data quality control systems when several contributors report their measurements to the collection of larger datasets. Beyond this, it can also provide a simple solution to investigate the accuracy of station classifications. Seen from another viewpoint, it can be used as a tool to detect irregular air pollution emission events (e.g. the influence of fires, wind erosion events, or other accidental situations). The presented procedure for outlier detection was designed based on already existing literature. Specifically, we adapted the "Smooth Spatial Attribute Method" that was first developed for the identification of outlier values in networks of traffic sensors [1]. Since a free and extensible simulation platform was considered important, all codes were prototyped in the R environment which is available under the GNU General Public License [2]. Our algorithms are based on the definition of a neighbourhood for each air quality measurement, corresponding to a spatio-temporal domain limited by time (e.g., +/- 2 days) and distance (e.g., +/- 1 spherical degrees) around the location of ambient air monitoring stations. The objective of the method is that within such a given spatio-temporal domain, in which

  16. PERSONAL COMPUTER MONITORS: A SCREENING EVALUATION OF VOLATILE ORGANIC EMISSIONS FROM EXISTING PRINTED CIRCUIT BOARD LAMINATES AND POTENTIAL POLLUTION PREVENTION ALTERNATIVES

    Science.gov (United States)

    The report gives results of a screening evaluation of volatile organic emissions from printed circuit board laminates and potential pollution prevention alternatives. In the evaluation, printed circuit board laminates, without circuitry, commonly found in personal computer (PC) m...

  17. Vision Screening

    Science.gov (United States)

    ... of Prematurity Strabismus Stye (defined) Vision Screening Vision Screening Recommendations Loading... Most Common Searches Adult Strabismus Amblyopia Cataract Conjunctivitis Corneal Abrasions Dilating Eye ...

  18. Facile high-throughput forward chemical genetic screening by in situ monitoring of glucuronidase-based reporter gene expression in Arabidopsis thaliana

    Directory of Open Access Journals (Sweden)

    Vivek eHalder

    2015-01-01

    Full Text Available The use of biologically active small molecules to perturb biological functions holds enormous potential for investigating complex signaling networks. However, in contrast to animal systems, the search for and application of chemical tools for basic discovery in the plant sciences, generally referred to as ‘chemical genetics’, has only recently gained momentum. In addition to cultured cells, the well-characterized, small-sized model plant Arabidopsis thaliana is suitable for cultivation in microplates, which allows employing diverse cell- or phenotype-based chemical screens. In such screens, a chemical’s bioactivity is typically assessed either through scoring its impact on morphological traits or quantifying molecular attributes such as enzyme or reporter activities. Here, we describe a facile forward chemical screening methodology for intact Arabidopsis seedlings harboring the β-glucuronidase (GUS reporter by directly quantifying GUS activity in situ with 4-methylumbelliferyl-β-D-glucuronide (4-MUG as substrate. The quantitative nature of this screening assay has an obvious advantage over the also convenient histochemical GUS staining method, as it allows application of statistical procedures and unbiased hit selection based on threshold values as well as distinction between compounds with strong or weak bioactivity. At the same time, the in situ bioassay is very convenient requiring less effort and time for sample handling in comparison to the conventional quantitative in vitro GUS assay using 4-MUG, as validated with several Arabidopsis lines harboring different GUS reporter constructs. To demonstrate that the developed assays is particularly suitable for large-scale screening projects, we performed a pilot screen for chemical activators or inhibitors of salicylic acid-mediated defense signaling using the Arabidopsis PR1p::GUS line. Importantly, the screening methodology provided here can be adopted for any inducible GUS reporter line.

  19. Mammography screening in Denmark

    DEFF Research Database (Denmark)

    Vejborg, Ilse; Mikkelsen, Ellen Margrethe; Garne, Jens Peter;

    2011-01-01

    Mammography screening is offered healthy women, and a high standard on professional and organizational level is mandatory not only in the screening programme but even in the diagnostic work-up and treatment. The main goal is to achieve a substantial reduction in disease specific mortality......, but it is not possible to evaluate the effect on mortality until several years later, and continuously monitoring of the quality of all aspects of a screening programme is necessary. Based on other European guidelines, 11 quality indicators have been defined, and guidelines concerning organizational requirements...

  20. Monitoring of smoking-induced emphysema with CT in a lung cancer screening setting : Detection of real increase in extent of emphysema

    NARCIS (Netherlands)

    Gietema, Hester A.; Schilham, Arnold M.; van Ginneken, Bram; van Klaveren, Rob J.; Lammers, Jan Willem J.; Prokop, Mathias

    2007-01-01

    Purose: To retrospectively establish the minimum increase in emphysema score (ES) required for detection of real Increased extent of emphysema with 95% confidence by using multi-detector row computed tomography (CT) in a lung cancer screening setting. Materials and Methods The study was a substudy o

  1. Fast and Highly Selective LC-MS/MS Screening for THC and 16 Other Abused Drugs and Metabolites in Human Hair to Monitor Patients for Drug Abuse

    NARCIS (Netherlands)

    Koster, Remco A.; Alffenaar, Jan-Willem C.; Greijdanus, Ben; VanDerNagel, Joanneke E. L.; Uges, Donald R. A.

    Background:To facilitate the monitoring of drug abuse by patients, a method was developed and validated for the analysis of amphetamine, methamphetamine, 3,4-methylenedioxymethamphetamine, methylenedioxyamphetamine, methylenedioxyethylamphetamine, methylphenidate, cocaine, benzoylecgonine, morphine,

  2. Fast and Highly Selective LC-MS/MS Screening for THC and 16 Other Abused Drugs and Metabolites in Human Hair to Monitor Patients for Drug Abuse

    NARCIS (Netherlands)

    Koster, Remco A.; Alffenaar, Jan-Willem C.; Greijdanus, Ben; VanDerNagel, Joanneke E. L.; Uges, Donald R. A.

    2014-01-01

    Background:To facilitate the monitoring of drug abuse by patients, a method was developed and validated for the analysis of amphetamine, methamphetamine, 3,4-methylenedioxymethamphetamine, methylenedioxyamphetamine, methylenedioxyethylamphetamine, methylphenidate, cocaine, benzoylecgonine, morphine,

  3. Depression Screening

    Science.gov (United States)

    ... Centers Diseases + Condition Centers Mental Health Medical Library Depression Screening (PHQ-9) - Instructions The following questions are ... this tool, there is also text-only version . Depression Screening - Manual Instructions The following questions are a ...

  4. Cancer Screening

    Directory of Open Access Journals (Sweden)

    Krishna Prasad

    2004-10-01

    Full Text Available Cancer screening is a means to detect cancer early with the goal of decreasing morbidity and mortality. At present, there is a reasonable consensus regarding screening for breast, cervical and colorectal cances and the role of screening is under trial in case of cancers of the lung,  ovaries and prostate. On the other hand, good screening tests are not available for some of the commonest cancers in India like the oral, pharyngeal, esophageal and stomach cancers.

  5. Cancer Screening

    OpenAIRE

    Krishna Prasad

    2004-01-01

    Cancer screening is a means to detect cancer early with the goal of decreasing morbidity and mortality. At present, there is a reasonable consensus regarding screening for breast, cervical and colorectal cances and the role of screening is under trial in case of cancers of the lung,  ovaries and prostate. On the other hand, good screening tests are not available for some of the commonest cancers in India like the oral, pharyngeal, esophageal and stomach cancers.

  6. Double screening

    Energy Technology Data Exchange (ETDEWEB)

    Gratia, Pierre [Department of Physics, University of Chicago,South Ellis Avenue, Chicago, IL 60637 (United States); Hu, Wayne [Department of Astronomy and Astrophysics, University of Chicago,South Ellis Avenue, Chicago, IL 60637 (United States); Enrico Fermi Institute and Kavli Institute for Cosmological Physics, University of Chicago,South Ellis Avenue, Chicago, IL 60637 (United States); Joyce, Austin [Enrico Fermi Institute and Kavli Institute for Cosmological Physics, University of Chicago,South Ellis Avenue, Chicago, IL 60637 (United States); Ribeiro, Raquel H. [School of Physics and Astronomy, Queen Mary University of London,Mile End Road, London, E1 4NS (United Kingdom)

    2016-06-15

    Attempts to modify gravity in the infrared typically require a screening mechanism to ensure consistency with local tests of gravity. These screening mechanisms fit into three broad classes; we investigate theories which are capable of exhibiting more than one type of screening. Specifically, we focus on a simple model which exhibits both Vainshtein and kinetic screening. We point out that due to the two characteristic length scales in the problem, the type of screening that dominates depends on the mass of the sourcing object, allowing for different phenomenology at different scales. We consider embedding this double screening phenomenology in a broader cosmological scenario and show that the simplest examples that exhibit double screening are radiatively stable.

  7. Colon cancer screening

    Science.gov (United States)

    Screening for colon cancer; Colonoscopy - screening; Sigmoidoscopy - screening; Virtual colonoscopy - screening; Fecal immunochemical test; Stool DNA test; sDNA test; Colorectal cancer - screening; Rectal ...

  8. 网络教学屏幕监控系统的设计与实现%The Design and Implementation of Network Teaching Screen Monitoring System

    Institute of Scientific and Technical Information of China (English)

    杨科; 韦家佳

    2014-01-01

    为了丰富程监控技术在教育教学的实践应用,结合高校教学的需求,基于Java+Socket+多线程技术,设计实现了一套网络教学屏幕监控系统,为师生构建数字化的学习环境提供了可能,从而实现有效的教学,提高了教学的质量。%In order to enrich the remote monitoring technology in the practice application of teaching and meet the requirements of the university teaching,design and implement a network teaching monitor system,which based on Java+Socket+Multi thread technology,ifling the possible away as construction of digital learning environment for teachers and students,achieving effective teaching and improving teaching quality.

  9. Pathogen Screening of Naturally Produced Yakima River Spring Chinook Smolts; Yakima/Klickitat Fisheries Project Monitoring and Evaluation Report 6 of 7, 2003-2004 Annual Report.

    Energy Technology Data Exchange (ETDEWEB)

    Thomas, Joan B. (Washington Department of Fish and Wildlife, Olympia, WA)

    2004-05-01

    In 1999 the Cle Elum Hatchery began releasing spring chinook salmon smolts into the upper Yakima River to increase natural production. Part of the evaluation of this program is to monitor whether introduction of hatchery produced smolts would impact the prevalence of specific pathogens in the naturally produced spring chinook smolts. Increases in prevalence of any of these pathogens could negatively impact the survival of these fish. In 1998 and 2000 through 2003 naturally produced smolts were collected for monitoring at the Chandler smolt collection facility on the lower Yakima River. Smolts were collected from mid to late outmigration, with a target of 200 fish each year. The pathogens monitored were infectious hematopoeitic necrosis virus, infectious pancreatic necrosis virus, viral hemorrhagic septicemia virus, Flavobacterium psychrophilum, Flavobacterium columnare, Aeromonas salmonicida, Yersinia ruckeri, Edwardsiella ictaluri, Renibacterium salmoninarum and Myxobolus cerebralis. To date, only the bacterial pathogens have been detected and prevalences have been low. Prevalences have varied each year and these changes are attributed to normal fluctuation of prevalence. All of the pathogens detected are widely distributed in Washington State.

  10. Energy-efficient implantable transmitter for restenosis monitoring with intelligent-stents.

    Science.gov (United States)

    Rivas, David; Miguel, Jose A; Lechuga, Yolanda; Allende, Miguel A; Martinez, Mar

    2015-01-01

    An analog circuit forming part of an intelligent-stent system is proposed with the aim of converting pressure-related capacitance measurements into a FM signal (around 800 MHz) to be analyzed outside of the patient body. Based on the information obtained from this signal, a reliable restenosis monitoring can be carried out. An energy-saver block controls the oscillator and reduces the power consumption of the whole circuit from 547.1 μW in active state to 152.1 μW in idle state, in order to comply with energy restriction imposed by inductive coupling powering. The design is implemented in TSMC 0.18 μm CMOS technology.

  11. A Dual-reporter system for real-time monitoring and high-throughput CRISPR/Cas9 library screening of the hepatitis C virus.

    Science.gov (United States)

    Ren, Qingpeng; Li, Chan; Yuan, Pengfei; Cai, Changzu; Zhang, Linqi; Luo, Guangxiang George; Wei, Wensheng

    2015-03-09

    The hepatitis C virus (HCV) is one of the leading causes of chronic hepatitis, liver cirrhosis and hepatocellular carcinomas and infects approximately 170 million people worldwide. Although several reporter systems have been developed, many shortcomings limit their use in the assessment of HCV infections. Here, we report a real-time live-cell reporter, termed the NIrD (NS3-4A Inducible rtTA-mediated Dual-reporter) system, which provides an on-off switch specifically in response to an HCV infection. Using the NIrD system and a focused CRISPR/Cas9 library, we identified CLDN1, OCLN and CD81 as essential genes for both the cell-free entry and the cell-to-cell transmission of HCV. The combination of this ultra-sensitive reporter system and the CRISPR knockout screening provides a powerful and high-throughput strategy for the identification of critical host components for HCV infections.

  12. Longitudinal Monitoring of Patients With Chronic Low Back Pain During Physical Therapy Treatment Using the STarT Back Screening Tool.

    Science.gov (United States)

    Medeiros, Flávia Cordeiro; Costa, Leonardo Oliveira Pena; Added, Marco Aurélio Nemitalla; Salomão, Evelyn Cassia; Costa, Lucíola da Cunha Menezes

    2017-05-01

    Study Design Preplanned secondary analysis of a randomized clinical trial. Background The STarT Back Screening Tool (SBST) was developed to screen and to classify patients with low back pain into subgroups for the risk of having a poor prognosis. However, this classification at baseline does not take into account variables that can influence the prognosis during treatment or over time. Objectives (1) To investigate the changes in risk subgroup measured by the SBST over a period of 6 months, and (2) to assess the long-term predictive ability of the SBST when administered at different time points. Methods Patients with chronic nonspecific low back pain (n = 148) receiving physical therapy care as part of a randomized trial were analyzed. Pain intensity, disability, global perceived effect, and the SBST were collected at baseline, 5 weeks, 3 months, and 6 months. Changes in SBST risk classification were calculated. Hierarchical linear regression models adjusted for potential confounders were built to analyze the predictive capabilities of the SBST when administered at different time points. Results A large proportion of patients (60.8%) changed their risk subgroup after receiving physical therapy care. The SBST improved the prediction for all 6-month outcomes when using the 5-week risk subgroup and the difference between baseline and 5-week subgroup, after controlling for potential confounders. The SBST at baseline did not improve the predictive ability of the models after adjusting for confounders. Conclusion This study shows that many patients change SBST risk subgroup after receiving physical therapy care, and that the predictive ability of the SBST in patients with chronic low back pain increases when administered at different time points. Level of Evidence Prognosis, 2b. J Orthop Sports Phys Ther 2017;47(5):314-323. Epub 29 Mar 2017. doi:10.2519/jospt.2017.7199.

  13. Application of Touch Screen in Monitoring and Control System of Compressor House%触摸屏在压风机房监控系统中的应用

    Institute of Scientific and Technical Information of China (English)

    史志鹏; 雷汝海; 靳文献

    2011-01-01

    Taking the design of monitoring and control system of compressor house of north ventilation shaft in No.8 Coal Mine of Pingdingshan Tian'an Mining Co., Ltd.as an example, the paper introduced characteristics and parameters of TPC1063E touch screen and MCGS configuration software, and gave general steps of configuration of the touch screen.It also gave implementation of project analysis,engineering framework, data object, graphic making, flow control, program debugging, driver programm of connection device and integration testing according to concrete conditions.The practical application showed that the touch screen works well and has easy operation because of friendly interface, which provides a guarantee for safe equiblast underground.%以平顶山天安煤业股份有限公司八矿北风井压风机房监控系统的设计为背景,介绍了TPC1063E触摸屏和MCGS组态软件的特点及相关参数,给出了触摸屏组态的一般步骤,并结合具体情况,依次给出了工程分析、工程框架、数据对象、图形制作、流程控制、程序调试、连接设备驱动程序、综合测试八个环节的具体实现.实际应用表明,该触摸屏运行良好,其友好的人机界面便于操作,为煤矿井下安全送风提供了保障.

  14. 基于监测成本收益分析的重点污染源筛选方法研究%Research on Method for Screening Intensive Pollution Sources Based on Monitoring Cost

    Institute of Scientific and Technical Information of China (English)

    叶维丽; 林凌; 吴悦颖

    2012-01-01

    对目前国家污染重点监控污染源筛选方法现状进行总结分析,从经济学角度提出运用成本收益分析方法.在考虑监测成本的前提下计算重点污染源单因子筛选比例的方法,是对累积污染负荷法的改进和补充,使国家重点污染源的筛选更为经济且科学有效.%In this paper, we summarized and analyzed the current screening method for national intensive Pollution Sources. Then we calculated the coefficient of single factor based on Cost-Benefit Analysis considering monitoring cost. This method offered improvement for Cumulative Pollution Load Method from an economic point of view which could screen national pollution sources more effective and scientific.

  15. Pathogen Screening of Naturally Produced Yakima River Spring Chinook Smolts; Yakima/Klickitat Fisheries Project Monitoring and Evaluation, 2002 Annual Report.

    Energy Technology Data Exchange (ETDEWEB)

    Thomas, Joan B. (Washington Department of Fish and Wildlife, Olympia, WA)

    2003-05-01

    In 1999 the Cle Elem Hatchery began releasing spring chinook smolts into the upper Yakima River for restoration and supplementation. This project was designed to evaluate whether introduction of intensively reared hatchery produced smolts would impact the prevalence of specific pathogens in the naturally produced spring chinook smolts. Increases in prevalence of any of these pathogens could negatively impact the survival of these fish. Approximately 200 smolts were collected at the Chandler smolt collection facility on the lower Yakima River during 1998, 2000 and 2001 and 130 smolts were collected in 2002 for monitoring for specific pathogens. The pathogens monitored were infectious hematopoeitic necrosis virus, infectious pancreatic necrosis virus, viral hemorrhagic septicemia, Flavobacterium psychrophilum, Flavobacterium columnare, Aeromonas salmonicida, Yersinia ruckeri, Edwardsiella ictaluri, Renibacterium salmoninarum and Myxobolus cerebralis. In addition the fish were tested for Ceratomyxa shasta spores in 2000 and 2001 (a correction from the 2001 report). To date, the only changes have been in the levels the bacterial pathogens in the naturally produced smolts and they have been minimal. These changes are attributed to normal fluctuation of prevalence.

  16. Pathogen Screening of Naturally Produced Yakima River Spring Chinook Smolts; Yakima/Klickitat Fisheries Project Monitoring and Evaluation, 2001 Annual Report.

    Energy Technology Data Exchange (ETDEWEB)

    Pearsons, Todd N.; Thomas, Joan B. (Washington Department of Fish and Wildlife, Olympia, WA)

    2003-01-01

    The change in pathogens prevalence to wild fish is probably the least studied ecological interaction associated with hatchery operations. In 1999, the Cle Elum Hatchery began releasing spring chinook smolts into the upper Yakima River to increase natural production. Part of the evaluation of this program is to evaluate whether introduction of hatchery produced smolts would impact the prevalence of specific pathogens in the naturally produced spring chinook smolts. Increases in prevalence of any of these pathogens could negatively impact the survival of these fish. Approximately 200 smolts were collected at the Chandler smolt collection facility on the lower Yakima River during 1998, 2000 and 2001 and monitored for specific pathogens. The pathogens monitored were infectious hematopoeitic necrosis virus, infectious pancreatic necrosis virus, viral hemorrhagic septicemia, Flavobacterium psychrophilum, Flavobacterium columnare, Aeromonas salmonicida, Yersinia ruckeri, Edwardsiella ictaluri, Renibacterium salmoninarum and Myxobolus cerebralis. In addition, the fish were tested for Ceratomyxa shasta spores in 2001. Not all testing has been completed for every year, but to date, there have only been minimal changes in levels of the bacterial pathogens in the naturally produced smolts. At this point, due to the limited testing so far, these changes are attributed to normal fluctuation of prevalence.

  17. Screening CO

    NARCIS (Netherlands)

    Ramírez, A.; Hagedoorn, S.; Kramers, L.; Wildenborg, T.; Hendriks, C.

    2010-01-01

    This paper describes the development and application of a methodology to screen and rank Dutch reservoirs suitable for long-term large scale CO2 storage. The screening focuses on off- and on-shore individual aquifers, gas and oil fields. In total 176 storage reservoirs have been taken int

  18. Quadruple screen test

    Science.gov (United States)

    Quad screen; Multiple marker screening; AFP plus; Triple screen test; AFP maternal; MSAFP; 4-marker screen; Down syndrome - quadruple; Trisomy 21 - quadruple; Turner syndrome - quadruple; Spina bifida - ...

  19. Toxicology screen

    Science.gov (United States)

    Toxicology screening is most often done using a blood or urine sample. However, it may be done soon after the person swallowed the medication, using stomach contents taken through gastric lavage (stomach pumping) or after vomiting.

  20. Hypertension screening

    Science.gov (United States)

    Foulke, J. M.

    1975-01-01

    An attempt was made to measure the response to an announcement of hypertension screening at the Goddard Space Center, to compare the results to those of previous statistics. Education and patient awareness of the problem were stressed.

  1. Hypertension screening

    Science.gov (United States)

    Foulke, J. M.

    1975-01-01

    An attempt was made to measure the response to an announcement of hypertension screening at the Goddard Space Center, to compare the results to those of previous statistics. Education and patient awareness of the problem were stressed.

  2. Clinical study on screening, monitoring and management of high risk pregnant women in Duanzhou district%端州区高危妊娠孕妇筛查、监测和管理的临床研究

    Institute of Scientific and Technical Information of China (English)

    蔡叶萍; 黄书炜; 吴爱芳; 彭飞玲; 胡劲

    2011-01-01

    Objective: To screen, monitor and manage high risk pregnant women in Duanzhou district of Zhaoqing city by information management network system, reduce maternal mortality, perinatal mortality and birth rate of disabled children. Methods: The pregnant women receiving prenatal examination in Duanzhou district of Zhangqing city from March 2007 to September 2008 were selected as primary group, information management network system was used to screen, monitor and manage high risk pregnant women in Duanzhou district of Zhaoqing city in March 2009; the pregnant women receiving prenatal examination in Duanzhou district from March 2009 to September 2010 were selected as control group, the data in primary group and control group were analyzed retrospectively. Results: The prevalence rate, follow - up rate and hospital delivery rate of high risk pregnant women in control group were higher than those in primary group, the rate of cesarean section, birth rate of disabled children, maternal mortality and perinatal mortality in control group were lower than those in primary group. Conclusion: Screening, monitoring and management of high risk pregnant women in Duanzhou district of Zhangqing city by information management network system can increase the prevalence rate, follow-up rate and hospital delivery rate of high risk pregnant women significantly,reduce the delivery complications of high risk pregnancy, the rate of cesarean section, birth rate of disabled children, maternal mortality and perinatal mortality effectively.%目的:应用信息管理网络系统对肇庆市端州区高危妊娠孕妇进行筛查、监测和管理;对降低孕产妇死亡率、围产儿死亡率和病残儿出生率有重要的意义.方法:将2007年3月~2008年9月在端州区产检的孕妇设为原发组,2009年3月应用信息管理网络系统对端州区高危妊娠孕妇进行筛查、监测和管理;将2009年3月~2010年9月在端州区产检的孕妇设为对照组,对原发组和

  3. Breast and cervical cancer screening programme implementation in 16 countries

    DEFF Research Database (Denmark)

    Dowling, Emily C; Klabunde, Carrie; Patnick, Julietta;

    2010-01-01

    There is a continuing need to monitor and evaluate the impact of organized screening programmes on cancer incidence and mortality. We report results from a programme assessment conducted within the International Cancer Screening Network (ICSN) to understand the characteristics of cervical screening...... programmes within countries that have established population-based breast cancer screening programmes....

  4. A novel assay for high-throughput screening of anti-Alzheimer's disease drugs to determine their efficacy by real-time monitoring of changes in PC12 cell proliferation.

    Science.gov (United States)

    Hou, Xue-Qin; Yan, Rong; Yang, Cong; Zhang, Lei; Su, Ru-Yu; Liu, Si-Jun; Zhang, Shi-Jie; He, Wen-Qing; Fang, Shu-Huan; Cheng, Shu-Yi; Su, Zi-Ren; Chen, Yun-Bo; Wang, Qi

    2014-03-01

    Alzheimer's disease (AD) is a neurodegenerative disease that is characterized by the accumulation of senile plaque and neurofibrilary tangle formation in the brain, including the cerebral cortex and hippocampus. Nowadays, the first-line treatment for AD is the application of acetylcholinesterase inhibitors. However, acetylcholinesterase inhibitors are basically anti-symptomatic for a limited aspect of AD pathology and are associated with serious side-effects. With the advantage of multiple targets, pathways and systems, Chinese herbal compounds hold promising potential for the development of drugs for the treatment of AD. Over the past few years, with the development of Chinese herbal compounds and in vitro pharmacological studies, cell-based disease models are one of the main methods used to screen Chinese herbal compounds for potential efficacy. Testing the efficacy of possible anti-Alzheimer's disease drugs and the development of new drugs are hindered by the lack of objective high-throughput screening methods. Currently, the assessment of the effects of drugs is usually made by MTT assays, involving laborious, subjective, low-throughput methods. Herein, we suggest a novel application for a real-time cell monitoring device (xCELLigence) that can simply and objectively assess the effective composition of Chinese herbal compounds by assessing amyloid-β peptide Aβ1-42-induced apoptosis in PC12 cells. We detected the proliferation and motility of the cells using a fully automated high-throughput and real-time system. We quantitatively assessed cell motility and determined the real-time IC50 values of various anti-AD drugs that intervene in several developmental stages of Aβ1-42-induced apoptosis in PC12 cells, Then, we identified the optimal time phase by curative efficacy. Our data indicate that this technique may aid in the discovery and development of novel anti-Alzheimer's disease drugs. It is possible to utilize a similar technique to measure changes in

  5. HCC screening; HCC-Screening

    Energy Technology Data Exchange (ETDEWEB)

    Albrecht, T. [Charite-Unversitaetsmedizin,Freie Universitaet und Humboldt-Universitaet zu Berlin, Klinik und Hochschulambulanz fuer Radiologie und Nuklearmedizin,Campus Benjamin Franklin, Berlin (Germany)

    2008-01-15

    Hepatocellular carcinoma (HCC) is one of the most frequently diagnosed tumour diseases throughout the world. In the vast majority of cases those affected are high-risk patients with chronic viral hepatitis and/or liver cirrhosis, which means there is a clearly identifiable target group for HCC screening. With resection, transplantation, and interventional procedures for local ablation, following early diagnosis curative treatment options are available with which 5-year survival rates of over 60% can be reached. Such early diagnosis is a reality only in a minority of patients, however, and in the majority of cases the disease is already in an advanced stage at diagnosis. One of the objects of HCC screening is diagnosis in an early stage when curative treatment is still possible. Precisely this is achieved by screening, so that the proportion of patients treated with curative intent is decisively higher. There is not yet any clear evidence as to whether this leads to a lowering of the mortality of HCC. As lower mortality is the decisive indicator of success for a screening programme the benefit of HCC screening has so far been neither documented nor refuted. Nonetheless, in large regions of the world it is the practice for high-risk patients to undergo HCC screening in the form of twice-yearly ultrasound examination and determination of AFP. (orig.) [German] Das hepatozellulaere Karzinom (HCC) ist eine der weltweit haeufigsten Tumorerkrankungen. Es tritt in der grossen Mehrzahl der Faelle bei Hochrisikopatienten mit chronischer Virushepatitis bzw. Leberzirrhose auf, woraus sich eine klar identifizierbare Zielgruppe fuer das HCC-Screening ergibt. Mit der Resektion, der Transplantation und interventionellen lokal ablativen Verfahren stehen bei rechtzeitiger Diagnosestellung kurative Therapieoptionen zur Verfuegung, die 5-Jahres-Ueberlebensraten von >60% erreichen. Diese rechtzeitige Diagnosestellung erfolgt jedoch nur bei einer Minderzahl der Patienten, waehrend die

  6. On large screen display system PTZ control of mine monitoring system in Yuhua coal mine%玉华煤矿监控系统大屏显示及云台控制

    Institute of Scientific and Technical Information of China (English)

    高明卿; 王东武

    2012-01-01

    The paper introduced the multi-channel video signal acquisition and processing,PIP display and adjustment of size and position of sub-picture of new monitoring system used in Yuhua coal mine.The system can completes the multi-channel video picture display on big screen and real time control of PTZ by processing the video data with FPGA and NiosII core.This technology has good effect in production scheduling and productivity promotion.%介绍了玉华煤矿新的监控系统,系统主要由图像采集模块、图像处理模块、图像显示模块以及云台控制模块构成。利用FPGA和NiosII核对数据量大、速度高、控制复杂的视频数据进行处理,从而完成多路视频图像在大屏幕上进行播放画中画及云台实时控制的功能,应用效果良好。

  7. Esophageal Cancer Screening

    Science.gov (United States)

    ... Esophageal Cancer Prevention Esophageal Cancer Screening Research Esophageal Cancer Screening (PDQ®)–Patient Version What is screening? Go to ... the esophagus and the stomach). Being overweight . Esophageal Cancer Screening Key Points Tests are used to screen for ...

  8. SCREEN CUISINE

    National Research Council Canada - National Science Library

    Heather Baysa

    2010-01-01

    ... from the legendary restaurant; the World's First FoodTruck Drive-In Movie on Saturday, where the city's finest food-truck vendors park for the screenings; and the Brooklyn Burger W Beer Garden on Sunday, serving up hearty burgers and brews while you watch Anat Baron's Beer Wars. Tonight at 7, Water Taxi Beach, South Street Seaport.fest...

  9. Airport Screening

    Science.gov (United States)

    ... must be limited to a safe level. An American National Standards Institute/Health Physics Society industry standard states that the maxi- mum ... that does not directly damage DNA. 2 References American National ... Physics Society. Radiation safety for personnel security screening systems ...

  10. Yeast two-hybrid screen.

    Science.gov (United States)

    Makuch, Lauren

    2014-01-01

    Yeast two-hybrid is a method for screening large numbers of gene products (encoded by cDNA libraries) for their ability to interact with a protein of interest. This system can also be used for characterizing and manipulating candidate protein: protein interactions. Interactions between proteins are monitored by the growth of yeast plated on selective media.

  11. Screening for human papillomavirus: is urine useful?

    NARCIS (Netherlands)

    D'Hauwers, K.W.M.; Tjalma, W.A.

    2009-01-01

    Persistent infection with high-risk Human papillomavirus (hr-HPV 16, 18, 31, 33, and 45) is the main risk factor for developing malignant genital lesions. Screening methods and follow-up schedules for cervical cancer are well known. A golden standard to screen and monitor men does not exist yet, bec

  12. Solutions for future pellet burning technologies - Pellet systems with active control with combined CO/O2 sensors - Pellet system with energy measuring and monitoring; Loesningar foer framtidens pelletsteknik - Pelletssystem med aktiv styrning med CO/O2-sensorer - Pelletssystem med energimaetning och fjaerroevervakning

    Energy Technology Data Exchange (ETDEWEB)

    Paulrud, Susanne; Ryde, Daniel; Roennbaeck, Marie

    2011-07-01

    To meet the consumer demands and the upcoming environmental regulations for the future Swedish heating system, development and improvement of the existing methods for combustion of fuel pellets are urged. In this study, two potential concepts - to be considered as important for the continued state-of-the-art improvement - for monitoring of the combustion process, have been demonstrated and evaluated. Within the project, SP Technical Research Institute of Sweden has, in co-operation with SenSiC, tested a new type of combined CO/O2 sensor. The sensor has been adapted to real combustion environment in a Jan Fire furnace, to which its control capacity has been verified. Moreover, a system for measuring the use of energy, EnergySaver, has, in co-operation with Effecta, been tested in a field study at the premises of a fuel pellet consumer. The SenSiC combined CO/O2 sensor has during the study progressively been developed and the resulting conclusion states that the product version FEI300-2 now is ready for further tests and market introduction. The trials show that the sensor reacts to an increase in emission levels, where after it manages to control the combustion process back to optimal level. The field study of the Effecta Energy Saver system shows that it, to a large part, is ready for commercial introduction. According to the fuel pellet consumer, the Effecta system increases the interest/awareness of energy saving.

  13. Breast cancer screening

    Science.gov (United States)

    Mammogram - breast cancer screening; Breast exam - breast cancer screening; MRI - breast cancer screening ... performed to screen women to detect early breast cancer when it is more likely to be cured. ...

  14. HMBS Pool-Level HECM Saver Data

    Data.gov (United States)

    Department of Housing and Urban Development — Disclosure Data Download makes available monthly disclosure information about Ginnie Mae MBS for periods 201204 and later. HMBS Monthly data is available for periods...

  15. Debye screening

    Science.gov (United States)

    Brydges, David C.; Federbush, Paul

    1980-10-01

    The existence and exponential clustering of correlation functions for a classical coulomb system at low density or high temperature are proven using methods from constructive quantum field theory, the sine gordon transformation and the Glimm, Jaffe, Spencer expansion about mean field theory. This is a vindication of a belief of long standing among physicists, known as Debye screening. That is, because of special properties of the coulomb potential, the configurations of significant probability are those in which the long range parts of r -1 are mostly cancelled, leaving an effective exponentially decaying potential acting between charge clouds. This paper generalizes a previous paper of one of the authors in which these results were obtained for a special lattice system. The present treatment covers the continuous mechanics situation, with essentially arbitrary short range forces and charge species. Charge symmetry is not assumed.

  16. Monitoring neonates for ototoxicity.

    Science.gov (United States)

    Garinis, Angela C; Kemph, Alison; Tharpe, Anne Marie; Weitkamp, Joern-Hendrik; McEvoy, Cynthia; Steyger, Peter S

    2017-06-22

    Neonates admitted to the neonatal intensive care unit (NICU) are at greater risk of permanent hearing loss compared to infants in well mother and baby units. Several factors have been associated with this increased prevalence of hearing loss, including congenital infections (e.g. cytomegalovirus or syphilis), ototoxic drugs (such as aminoglycoside or glycopeptide antibiotics), low birth weight, hypoxia and length of stay. The aetiology of this increased prevalence of hearing loss remains poorly understood. Here we review current practice and discuss the feasibility of designing improved ototoxicity screening and monitoring protocols to better identify acquired, drug-induced hearing loss in NICU neonates. A review of published literature. We conclude that current audiological screening or monitoring protocols for neonates are not designed to adequately detect early onset of ototoxicity. This paper offers a detailed review of evidence-based research, and offers recommendations for developing and implementing an ototoxicity monitoring protocol for young infants, before and after discharge from the hospital.

  17. Methods for Cervical Cancer Screening

    Directory of Open Access Journals (Sweden)

    Tatiana Vargas-Revilla

    2014-12-01

    This article is divided in three sections: the first one focuses on the general impact of cervical cancer has hadin CostaRica, these condsection gathers information about different methodologies used around the world to detect this cancer and the third one makes reference to the current development of the screening devise in Mexico that works as a monitoring system and can used by women without external assistance.

  18. Mental Health Screening Center

    Science.gov (United States)

    ... Releases & Announcements Public Service Announcements Partnering with DBSA Mental Health Screening Center These online screening tools are not ... you have any concerns, see your doctor or mental health professional. Depression This screening form was developed from ...

  19. Lung Cancer Screening

    Science.gov (United States)

    ... Treatment Lung Cancer Prevention Lung Cancer Screening Research Lung Cancer Screening (PDQ®)–Patient Version What is screening? Go ... These are called diagnostic tests . General Information About Lung Cancer Key Points Lung cancer is a disease in ...

  20. Skin Cancer Screening

    Science.gov (United States)

    ... Genetics of Skin Cancer Skin Cancer Screening Research Skin Cancer Screening (PDQ®)–Patient Version What is screening? ... These are called diagnostic tests . General Information About Skin Cancer Key Points Skin cancer is a disease ...

  1. Testicular Cancer Screening

    Science.gov (United States)

    ... Health Professional Testicular Cancer Treatment Testicular Cancer Screening Testicular Cancer Screening (PDQ®)–Patient Version What is screening? Go ... These are called diagnostic tests . General Information About Testicular Cancer Key Points Testicular cancer is a disease in ...

  2. Prenatal screening and genetics

    DEFF Research Database (Denmark)

    Alderson, P; Aro, A R; Dragonas, T

    2001-01-01

    Although the term 'genetic screening' has been used for decades, this paper discusses how, in its most precise meaning, genetic screening has not yet been widely introduced. 'Prenatal screening' is often confused with 'genetic screening'. As we show, these terms have different meanings, and we...... examine definitions of the relevant concepts in order to illustrate this point. The concepts are i) prenatal, ii) genetic screening, iii) screening, scanning and testing, iv) maternal and foetal tests, v) test techniques and vi) genetic conditions. So far, prenatal screening has little connection...... with precisely defined genetics. There are benefits but also disadvantages in overstating current links between them in the term genetic screening. Policy making and professional and public understandings about screening could be clarified if the distinct meanings of prenatal screening and genetic screening were...

  3. Recording the Amount of Attention Given to Various Portions of the Screen.

    Science.gov (United States)

    Mielke, Keith W.

    Most devices designed to monitor the part of a visual display on which a subject's eyes are focused are cumbersome and expensive. It is proposed that areas of the display screen designated by the production unit as important to some decision be isolated on one television monitor and the remaining area of the screen be isolated on a second monitor.…

  4. Danish Quality Database for Mammography Screening

    DEFF Research Database (Denmark)

    Mikkelsen, Ellen Margrethe; Njor, Sisse Helle; Vejborg, Ilse Merete Munk

    2016-01-01

    AIM: The Danish Quality Database for Mammography Screening (DKMS) was established in 2007, with the aim to monitor, sustain, and improve the quality of the Danish national breast cancer screening program. STUDY POPULATION: All Danish women aged 50-69 years who were invited every 2 years for breast...... required to determine the following eleven indicators: 1) radiation exposure, 2) participation among invited women and participation within the target population, 3) time between screening and result, 4) screening interval, 5) recall for further diagnostics, 6) interval cancers consisting of women...... working days, 2.7% of the screened women were recalled for further diagnostics, 82% of the women operated for invasive carcinomas were node negative, and 40% of the women had the tumor size of ≤10 mm. CONCLUSION: The DKMS has successfully evaluated the quality of the nationwide Danish breast cancer...

  5. Stomach (Gastric) Cancer Screening

    Science.gov (United States)

    ... Gastric Cancer Treatment Stomach Cancer Prevention Stomach Cancer Screening Research Stomach (Gastric) Cancer Screening (PDQ®)–Patient Version What is ... from the . There is no standard or routine screening test for stomach cancer. Several types of screening tests have been ...

  6. Prenatal screening and genetics

    NARCIS (Netherlands)

    Alderson, P.; Aro, A.R.; Dragonas, T.; Ettorre, E.; Hemminki, E.; Jalinoja, P.; Santalahti, P.; Tijmstra, T.

    Although the term 'genetic screening' has been used for decades, this paper discusses how, in its most precise meaning, genetic screening has not yet been widely introduced. 'Prenatal screening' is often confused with 'genetic screening'. As we show, these terms have different meanings, and we

  7. Prenatal screening and genetics

    NARCIS (Netherlands)

    Alderson, P.; Aro, A.R.; Dragonas, T.; Ettorre, E.; Hemminki, E.; Jalinoja, P.; Santalahti, P.; Tijmstra, T.

    2001-01-01

    Although the term 'genetic screening' has been used for decades, this paper discusses how, in its most precise meaning, genetic screening has not yet been widely introduced. 'Prenatal screening' is often confused with 'genetic screening'. As we show, these terms have different meanings, and we exami

  8. Prenatal screening and genetics

    DEFF Research Database (Denmark)

    Alderson, P; Aro, A R; Dragonas, T

    2001-01-01

    Although the term 'genetic screening' has been used for decades, this paper discusses how, in its most precise meaning, genetic screening has not yet been widely introduced. 'Prenatal screening' is often confused with 'genetic screening'. As we show, these terms have different meanings, and we ex...

  9. Biomarkers in Cervical Cancer Screening

    Directory of Open Access Journals (Sweden)

    Nicolas Wentzensen

    2007-01-01

    Full Text Available In industrialized countries, population wide cytological screening programs using the Pap test have led to a substantial reduction of the incidence of cervical cancer. Despite this evident success, screening programs that rely on Pap-stained cytological samples have several limitations. First, a number of equivocal or mildly abnormal test results require costly work up by either repeated retesting or direct colposcopy and biopsy, since a certain percentage of high grade lesions that require immediate treatment hide among these unclear test results. This work up of mildly abnormal or equivocal cytological tests consumes a large amount of the overall costs spent for cervical cancer screening. Improved triage of these samples might substantially reduce the costs. Cervical cancer is induced by persistent infections with oncogenic human papilloma viruses (HPV. While HPV infection is an indispensable factor, it is not sufficient to cause cancer. The majority of acute HPV infections induce low grade precursor lesions that are cleared spontaneously after several months in more than 90% of cases, and less than 10% eventually progress to high grade lesions or invasive cancer. Progression is characterized by the deregulated expression of the viral oncogenes E6 and E7 in infected basal and parabasal cells. Novel biomarkers that allow monitoring these essential molecular events in histological or cytological specimens are likely to improve the detection of lesions that have a high risk of progression in both primary screening and triage settings. In this review, we will discuss potential biomarkers for cervical cancer screening with a focus on the level of clinical evidence that supports their application as novel markers in refined cervical cancer screening programs.

  10. Screening for abdominalt aortaaneurisme

    DEFF Research Database (Denmark)

    Lindholt, J S; Juul, Svend; Henneberg, E W;

    1997-01-01

    rupture. Ultrasonographic screening for AAA takes 10 minutes per scan, and the sensitivity and specificity are high. Ultrasonographic screening for AAA is a reliable, safe and inexpensive method for screening, and screening for AAA is discussed worldwide. One point four percent of deaths among men from 65...... on uncertain assumptions concerning prevalence, incidence and risk of rupture. Therefore a randomized trial screening of 65-73 year old males is taking place in the County of Viborg in Denmark. Udgivelsesdato: 1997-Mar-24...

  11. Screening for abdominalt aortaaneurisme

    DEFF Research Database (Denmark)

    Lindholt, Jes Sanddal; Juul, Søren; Henneberg, E W;

    1997-01-01

    rupture. Ultrasonographic screening for AAA takes 10 minutes per scan, and the sensitivity and specificity are high. Ultrasonographic screening for AAA is a reliable, safe and inexpensive method for screening, and screening for AAA is discussed worldwide. One point four percent of deaths among men from 65...... on uncertain assumptions concerning prevalence, incidence and risk of rupture. Therefore a randomized trial screening of 65-73 year old males is taking place in the County of Viborg in Denmark....

  12. Risks of Esophageal Cancer Screening

    Science.gov (United States)

    ... Esophageal Cancer Prevention Esophageal Cancer Screening Research Esophageal Cancer Screening (PDQ®)–Patient Version What is screening? Go to ... the esophagus and the stomach). Being overweight . Esophageal Cancer Screening Key Points Tests are used to screen for ...

  13. ORR Deer Hunt Monitoring Program

    Energy Technology Data Exchange (ETDEWEB)

    Scofield, P.A.; Teasley, N.A.

    1999-09-01

    The primary purpose for the initiation of deer hunts on the Oak Ridge Reservation (ORR) was deer population control to reduce collisions with vehicles and maintain a healthy herd and habitat. As of 1997, thirteen annual deer hunts have been conducted on the ORR. The deer hunt monitoring program (DHMP) has two components -- a field screening monitoring program and a confirmatory laboratory analysis program of both retained and randomly selected released deer samples.

  14. Computer monitors drilling performance

    Energy Technology Data Exchange (ETDEWEB)

    1984-05-01

    Computer systems that can monitor over 40 drilling variables, display them graphically, record and transmit the information have been developed separately by two French companies. The systems, Vigigraphic and Visufora, involve the linking of a master computer with various surface and downhole sensors to measure the data on a real-time (as experienced) basis and compute the information. Vigigraphic is able to produce graphic displays grouped on four screens - drilling, tripping, geological and mud data. It computes at least 200 variables from the sensor readings, and it can store over 100 variables. Visufora allows the operator to group the drilling variables as desired. It can monitor and analyze surface and downhole parameters. The system can be linked with MWD tools. Twenty channels of input are assigned to surface values and the remaining 20 channels can be used to monitor downhole instrumentation.

  15. Hearing Loss: Screening Newborns

    Science.gov (United States)

    ... of this page please turn JavaScript on. Feature: Hearing Loss Screening Newborns Past Issues / Spring 2015 Table of ... of newborns in the U.S. are screened for hearing loss before they leave the hospital. Research improves the ...

  16. Cervical Cancer Screening

    Science.gov (United States)

    ... Cancer found early may be easier to treat. Cervical cancer screening is usually part of a woman's health ... may do more tests, such as a biopsy. Cervical cancer screening has risks. The results can sometimes be ...

  17. Screening for Cervical Cancer

    Science.gov (United States)

    Understanding Task Force Recommendations Screening for Cervical Cancer The U.S. Preventive Services Task Force (Task Force) has issued final recommendations on Screening for Cervical Cancer . These recommendations are for women ...

  18. Screening for Ovarian Cancer

    Science.gov (United States)

    Understanding Task Force Recommendations Screening for Ovarian Cancer The U.S. Preventive Services Task Force (Task Force) has issued a final recommendation on Screening for Ovarian Cancer . This recommendation is for ...

  19. Video Screen Capture Basics

    Science.gov (United States)

    Dunbar, Laura

    2014-01-01

    This article is an introduction to video screen capture. Basic information of two software programs, QuickTime for Mac and BlueBerry Flashback Express for PC, are also discussed. Practical applications for video screen capture are given.

  20. Prostate Cancer Screening

    Science.gov (United States)

    ... a man's bladder that produces fluid for semen. Cancer screening is looking for cancer before you have any ... as an ultrasound, MRI, or a biopsy. Prostate cancer screening has risks: Finding prostate cancer may not improve ...

  1. Alcohol Use Screening

    Science.gov (United States)

    ... Centers Diseases + Condition Centers Mental Health Medical Library Alcohol Use Screening (AUDIT-C) - Instructions The following questions ... this tool, there is also text-only version . Alcohol Use Screening (AUDIT-C) - Manual Instructions The following ...

  2. Endometrial Cancer Screening

    Science.gov (United States)

    ... Transvaginal ultrasound Endometrial sampling Tests are used to screen for different types of cancer. Some screening tests ... endometrium by inserting a brush, curette , or thin, flexible tube through the cervix and into the uterus. ...

  3. Screening for Glaucoma

    Science.gov (United States)

    Understanding Task Force Recommendations Screening for Glaucoma The U.S. Preventive Services Task Force (Task Force) has issued a final recommendation statement on Screening for Glaucoma . This final recommendation statement ...

  4. Colorectal cancer screening.

    Science.gov (United States)

    Burt, Randall W; Cannon, Jamie A; David, Donald S; Early, Dayna S; Ford, James M; Giardiello, Francis M; Halverson, Amy L; Hamilton, Stanley R; Hampel, Heather; Ismail, Mohammad K; Jasperson, Kory; Klapman, Jason B; Lazenby, Audrey J; Lynch, Patrick M; Mayer, Robert J; Ness, Reid M; Provenzale, Dawn; Rao, M Sambasiva; Shike, Moshe; Steinbach, Gideon; Terdiman, Jonathan P; Weinberg, David; Dwyer, Mary; Freedman-Cass, Deborah

    2013-12-01

    Mortality from colorectal cancer can be reduced by early diagnosis and by cancer prevention through polypectomy. These NCCN Guidelines for Colorectal Cancer Screening describe various colorectal screening modalities and recommended screening schedules for patients at average or increased risk of developing colorectal cancer. In addition, the guidelines provide recommendations for the management of patients with high-risk colorectal cancer syndromes, including Lynch syndrome. Screening approaches for Lynch syndrome are also described.

  5. Screening for Lung Cancer

    Science.gov (United States)

    Mazzone, Peter J.; Naidich, David P.; Bach, Peter B.

    2013-01-01

    Background: Lung cancer is by far the major cause of cancer deaths largely because in the majority of patients it is at an advanced stage at the time it is discovered, when curative treatment is no longer feasible. This article examines the data regarding the ability of screening to decrease the number of lung cancer deaths. Methods: A systematic review was conducted of controlled studies that address the effectiveness of methods of screening for lung cancer. Results: Several large randomized controlled trials (RCTs), including a recent one, have demonstrated that screening for lung cancer using a chest radiograph does not reduce the number of deaths from lung cancer. One large RCT involving low-dose CT (LDCT) screening demonstrated a significant reduction in lung cancer deaths, with few harms to individuals at elevated risk when done in the context of a structured program of selection, screening, evaluation, and management of the relatively high number of benign abnormalities. Whether other RCTs involving LDCT screening are consistent is unclear because data are limited or not yet mature. Conclusions: Screening is a complex interplay of selection (a population with sufficient risk and few serious comorbidities), the value of the screening test, the interval between screening tests, the availability of effective treatment, the risk of complications or harms as a result of screening, and the degree with which the screened individuals comply with screening and treatment recommendations. Screening with LDCT of appropriate individuals in the context of a structured process is associated with a significant reduction in the number of lung cancer deaths in the screened population. Given the complex interplay of factors inherent in screening, many questions remain on how to effectively implement screening on a broader scale. PMID:23649455

  6. Between Stage and Screen

    NARCIS (Netherlands)

    Tornqvist, Egil

    1996-01-01

    Ingmar Bergman is worldwide known as a film and stage director. Yet no-one has attempted to compare his stage and screen activities. In Between stage and screen Egil Tornqvist examines formal and thematical correspondences and differences between a number of Bergman's stage, screen, and radio produc

  7. Screen time and children

    Science.gov (United States)

    ... obesity ) Screen time increases your child's risk of obesity because: Sitting and watching a screen is time that is not spent being physically active. TV commercials and other screen ads can lead to unhealthy food choices . Most of the time, the foods in ads ...

  8. Screen Practice in Curating

    DEFF Research Database (Denmark)

    Toft, Tanya Søndergaard

    2014-01-01

    During the past one and a half decade, a curatorial orientation towards "screen practice" has expanded the moving image and digital art into the public domain, exploring alternative artistic uses of the screen. The emergence of urban LED screens in the late 1990s provided a new venue that allowed...

  9. Principles of Cancer Screening.

    Science.gov (United States)

    Pinsky, Paul F

    2015-10-01

    Cancer screening has long been an important component of the struggle to reduce the burden of morbidity and mortality from cancer. Notwithstanding this history, many aspects of cancer screening remain poorly understood. This article presents a summary of basic principles of cancer screening that are relevant for researchers, clinicians, and public health officials alike. Published by Elsevier Inc.

  10. Breast awareness and screening.

    Science.gov (United States)

    Harmer, Victoria

    Breast cancer is the most commonly diagnosed cancer in the UK. Breast awareness and screening, along with better treatment, can significantly improve outcomes, and more women than ever are now surviving the disease. This article discusses breast awareness and screening, symptoms and risk factors for breast cancer, and how nurses can raise breast awareness and screening uptake.

  11. Screening for colorectal cancer.

    Science.gov (United States)

    He, Jin; Efron, Jonathan E

    2011-01-01

    March is national colorectal cancer awareness month. It is estimated that as many as 60% of colorectal cancer deaths could be prevented if all men and women aged 50 years or older were screened routinely. In 2000, Katie Couric's televised colonoscopy led to a 20% increase in screening colonoscopies across America, a stunning rise called the "Katie Couric Effect". This event demonstrated how celebrity endorsement affects health behavior. Currently, discussion is ongoing about the optimal strategy for CRC screening, particularly the costs of screening colonoscopy. The current CRC screening guidelines are summarized in Table 2. Debates over the optimum CRC screening test continue in the face of evidence that 22 million Americans aged 50 to 75 years are not screened for CRC by any modality and 25,000 of those lives may have been saved if they had been screened for CRC. It is clear that improving screening rates and reducing disparities in underscreened communities and population subgroups could further reduce colorectal cancer morbidity and mortality. National Institutes of Health consensus identified the following priority areas to enhance the use and quality of colorectal cancer screening: Eliminate financial barriers to colorectal cancer screening and appropriate follow-up of positive results of colorectal cancer screening. Develop systems to ensure the high quality of colorectal cancer screening programs. Conduct studies to determine the comparative effectiveness of the various colorectal cancer screening methods in usual practice settings. Encouraging population adherence to screening tests and allowing patients to select the tests they prefer may do more good (as long as they choose something) than whatever procedure is chosen by the medical profession as the preferred test.

  12. [Colorectal cancer screening].

    Science.gov (United States)

    Castells, Antoni

    2015-09-01

    Colorectal cancer is one of malignancies showing the greatest benefit from preventive measures, especially screening or secondary prevention. Several screening strategies are available with demonstrated efficacy and efficiency. The most widely used are the faecal occult blood test in countries with population-based screening programmes, and colonoscopy in those conducting opportunistic screening. The present article reviews the most important presentations on colorectal cancer screening at the annual congress of the American Gastroenterological Association held in Washington in 2015, with special emphasis on the medium-term results of faecal occult blood testing strategies and determining factors and on strategies to reduce the development of interval cancer after colonoscopy.

  13. Screen Practice in Curating

    DEFF Research Database (Denmark)

    Toft, Tanya Søndergaard

    2014-01-01

    During the past one and a half decade, a curatorial orientation towards "screen practice" has expanded the moving image and digital art into the public domain, exploring alternative artistic uses of the screen. The emergence of urban LED screens in the late 1990s provided a new venue that allowed...... for digital art to expand into public space. It also offered a political point of departure, inviting for confrontation with the Spectacle and with the politics and ideology of the screen as a mass communication medium that instrumentalized spectator positions. In this article I propose that screen practice...... to the dispositif of screen practice in curating, resulting in a medium-based curatorial discourse. With reference to the nomadic exhibition project Nordic Outbreak that I co-curated with Nina Colosi in 2013 and 2014, I suggest that the topos of the defined visual display area, frequently still known as "the screen...

  14. Population screening for Wilson's disease.

    Science.gov (United States)

    Hahn, Si Houn

    2014-05-01

    Wilson's disease is an autosomal recessive disorder of copper transport caused by mutations in the gene encoding an ATPase, ATP7B. Early detection of Wilson's disease is critical because effective medical treatments such as chelating agents and zinc salts are available, which can prevent lifelong neurological disabilities and/or cirrhosis. It is unfortunate that most patients are brought to our attention after they have developed serious complications such as brain damage or cirrhosis, despite the availability of effective treatments. The diagnosis is usually made through copper measurement in the liver tissue, followed by confirmation with genetic testing of the ATP7B gene. Currently, there are no effective biomarkers or methods suitable for newborn screening for Wilson's disease. Ceruloplasmin has been tested for pediatric and newborn screening with limited outcome. Recently, liquid chromatography-multiple reaction monitoring-mass spectrometry (LC-MRM-MS) has emerged as a robust technology that may enable multiplex quantification of signature proteotypic peptides with low abundance. The application of this technology may help facilitate the research on Wilson's disease for protein expression, biomarker study, diagnosis, and, hopefully, screening.

  15. Attendance in cancer screening programmes in Italy

    Directory of Open Access Journals (Sweden)

    Grazia Grazzini

    2008-06-01

    Full Text Available

    Background: The European Community recommends mammography, cervical and colorectal cancer screening programmes. In Italy, cancer screening programmes have been included in the Basic Healthcare Parameters (Livelli Essenziali di Assistenza since 2001. Full national coverage of a population-based organized screening programme has been planned for in Italy and is being implemented. Since 2005, the Ministry of Health - Department of Prevention has formally charged The National Centre for Screening Monitoring (Osservatorio Nazionale Screening –ONS- with monitoring and promoting screening programmes nationwide. Participation of target populations is a key indicator of the impact and efficacy of a screening programme in reducing cancer mortality.

    Methods: Attendance of invitees is one of the indicators calculated every year in the quality control of Italian screening programmes. Data collection is organized by means of a structured questionnaire, sent by ONS to the referent for data collection in each Region, who then returns the completed questionnaires to the Regional Centre. Questionnaires are then sent to the National Centre. Logical and epidemiologic checks are performed at both levels. Every year ONS publishes reports on the results of the surveys. A feasibility study for a National data warehouse based on individual records is in progress. The national survey “Multiscopo sulle famiglie” and the Passi Study (Progetti delle Aziende Sanitarie per la Salute in Italia provided additional information regarding spontaneous preventive health care activities in the Italian population.

    Results: Mammography screening: In 2006, 78.2% of Italian women aged 50-69 lived in areas where organised screening was in place (theoretical extension, however, the distribution of the screening activity is not uniform (higher in Northern/Central Italy compared with Southern

  16. 老年慢性病患者营养风险筛查及监测分析%Analysis of Senile Patients with Chronic Disease Nutrition Risk Screening and Monitoring

    Institute of Scientific and Technical Information of China (English)

    王维业; 赖成毅

    2013-01-01

    Objective:To investigate and analyse the nutritional risk and nutritional support of different patients in geriatric. Method:Used nutritional risk screening NRS2002,three variable regression method and nutritional risk index screening methods,combined with the measured index of human body,important laboratory examination indexes of nutrition,as well as the direct searched and read the record,understood the recent body weight and dietary changes as the reference,comprehensive analysis and assessment,200 patients were investigated from July 2011 to December. Result:The rates of malnutrition and nutritional risk were 40.00%and 50.55%,the respiratory diseases and malignant tumors and gastrointestinal tract disease had higher incidence of nutritional risk. They were 55.00%,86.66%,66.66%,other diseases were the second,and the corresponding nutritional support therapy. Conclusion:Elderly patients should be performed routinely a variety of nutritional risk screening,a variety of integrated application of evaluation way,in order to improve the timeliness and scientific and rationality of clinical nutritional support.%目的:调查分析老年病科不同情况患者的营养风险及营养支持状况。方法:对2012年7-12月200例入院患者进行调查,采用营养风险筛查NRS2002、三元回归法及营养风险指数筛查方法,结合人体测量指标、重要营养实验室检查指标、以及直接查询和阅读病历记录方式了解近期体重及饮食变化等为参考依据,综合进行分析评估。结果:营养不足和营养风险发生率分别为40.00%(72/180)和50.55%(91/180),其中以呼吸道疾病、恶性肿瘤及胃肠道疾病营养风险发生率较高,分别55.00%、86.66%、66.66%,其他系统疾病次之,并进行相应的营养支持治疗。结论:在老年患者中应常规进行营养风险筛查,多种评估方式综合应用,以提高临床营养支持的合理性、及时性和科学性。

  17. Screening in liver disease

    Institute of Scientific and Technical Information of China (English)

    Paolo Del Poggio; Marzio Mazzoleni

    2006-01-01

    A disease is suitable for screening if it is common, if the target population can be identified and reached and if both a good screening test and an effective therapy are available. Of the most common liver diseases only viral hepatitis and genetic hemochromatosis partially satisfy these conditions. Hepatitis C is common, the screening test is good and the therapy eliminates the virus in half of the cases, but problems arise in the definition of the target population. In fact generalized population screening is not endorsed by international guidelines,although some recommend screening immigrants from high prevalence countries. Opportunistic screening (case finding) of individuals with classic risk factors,such as transfusion before 1992 and drug addiction,is the most frequently used strategy, but there is disagreement whether prison inmates, individuals with a history of promiscuous or traumatic sex and health care workers should be screened. In a real practice setting the performance of opportunistic screening by general practitioners is low but can be ameliorated by training programs. Screening targeted to segments of the population or mass campaigns are expensive and therefore interventions should be aimed to improve opportunistic screening and the detection skills of general practitioners. Regarding genetic hemochromatosis there is insufficient evidence for population screening, but individual physicians can decide to screen racial groups with a high prevalence of the disease, such as people in early middle age and of northern European origin. In the other cases opportunistic screening of high risk individuals should be performed, with a high level of suspicion in case of unexplained liver disease, diabetes, juvenile artropathy, sexual dysfunction and skin pigmentation.

  18. Screen failure data in clinical trials: Are screening logs worth it?

    Science.gov (United States)

    Elm, Jordan J; Palesch, Yuko; Easton, J Donald; Lindblad, Anne; Barsan, William; Silbergleit, Robert; Conwit, Robin; Dillon, Catherine; Farrant, Mary; Battenhouse, Holly; Perlmutter, Aaron; Johnston, S Claiborne

    2014-08-01

    Clinical trials frequently spend considerable effort to collect data on patients who were assessed for eligibility but not enrolled. The Consolidated Standards of Reporting Trials (CONSORT) guidelines' recommended flow diagram for randomized clinical trials reinforces the belief that the collection of screening data is a necessary and worthwhile endeavor. The rationale for collecting screening data includes scientific, trial management, and ethno-socio-cultural reasons. We posit that the cost of collecting screening data is not justified, in part due to inability to centrally monitor and verify the screening data in the same manner as other clinical trial data. To illustrate the effort and site-to-site variability, we analyzed the screening data from a multicenter, randomized clinical trial of patients with transient ischemic attack or minor ischemic stroke (Platelet-Oriented Inhibition in New Transient Ischemic Attack and Minor Ischemic Stroke (POINT)). Data were collected on over 27,000 patients screened across 172 enrolling sites, 95% of whom were not enrolled. Although the rate of return of screen failure logs was high overall (95%), there were a considerable number of logs that were returned with 'no data to report' (23%), often due to administrative reasons rather than no patients screened. In spite of attempts to standardize the collection of screening data, due to differences in site processes, multicenter clinical trials face challenges in collecting those data completely and uniformly. The efforts required to centrally collect high-quality data on an extensive number of screened patients may outweigh the scientific value of the data. Moreover, the lack of a standardized definition of 'screened' and the challenges of collecting meaningful characteristics for patients who have not signed consent limits the ability to compare across studies and to assess generalizability and selection bias as intended. © The Author(s), 2014.

  19. Screening for colorectal cancer

    DEFF Research Database (Denmark)

    Nielsen, Hans J; Jakobsen, Karen V; Christensen, Ib J

    2011-01-01

    Emerging results indicate that screening improves survival of patients with colorectal cancer. Therefore, screening programs are already implemented or are being considered for implementation in Asia, Europe and North America. At present, a great variety of screening methods are available including...... into improvements of screening for colorectal cancer includes blood-based biological markers, such as proteins, DNA and RNA in combination with various demographically and clinically parameters into a "risk assessment evaluation" (RAE) test. It is assumed that such a test may lead to higher acceptance among...... procedures for colorectal cancer. Therefore, results of present research, validating RAE tests, are awaited with interest....

  20. Lung cancer screening

    Energy Technology Data Exchange (ETDEWEB)

    Kazerooni, E.A. [Univ. of Michigan Medical Center, Ann Arbor, MI (United States)

    2005-11-15

    Lung cancer screening with CT remains controversial. Lung cancer is the leading cause of cancer death. To date, no screening test has been demonstrated to reduce mortality. Given the large population of adult cigarette smokers and former smokers worldwide, there is a large population at risk for lung cancer. While a lot has been learned from prospective single-arm cohort studies about the feasibility of performing annual CT to screen for lung cancer, many questions have also been raised. While we know that screening for lung cancer with CT detects many small nodules, with up to half the subjects having a positive baseline screen, and up to 75% of subjects having a positive screen at least once if screened annually for 5 years, the great majority of these nodules exhibit benign biologic behavior. The innumerable small nodules detected with screening CT, and diagnostic chest CT in general, present a daily clinical challenge, and result in extensive medical resource utilization and additional radiation exposure. Algorithms for how and when to follow small nodules detected on CT are in evolution. Ongoing studies are designed to determine if lung cancer screening with CT reduces lung cancer mortality. (orig.)

  1. [Overdiagnosis in cancer screening].

    Science.gov (United States)

    Cervera Deval, J; Sentís Crivillé, M; Zulueta, J J

    2015-01-01

    In screening programs, overdiagnosis is defined as the detection of a disease that would have gone undetected without screening when that disease would not have resulted in morbimortality and was treated unnecessarily. Overdiagnosis is a bias inherent in screening and an undesired effect of secondary prevention and improved sensitivity of diagnostic techniques. It is difficult to discriminate a priori between clinically relevant diagnoses and those in which treatment is unnecessary. To minimize the effects of overdiagnosis, screening should be done in patients at risk. Copyright © 2014 SERAM. Published by Elsevier España, S.L.U. All rights reserved.

  2. Colorectal cancer screening.

    Science.gov (United States)

    Chan, Pak Wo Webber; Ngu, Jing Hieng; Poh, Zhongxian; Soetikno, Roy

    2017-01-01

    Colorectal cancer, which is the leading cancer in Singapore, can be prevented by increased use of screening and polypectomy. A range of screening strategies such as stool-based tests, flexible sigmoidoscopy, colonoscopy and computed tomography colonography are available, each with different strengths and limitations. Primary care physicians should discuss appropriate screening modalities with their patients, tailored to their individual needs. Physicians, patients and the government should work in partnership to improve uptake of colorectal cancer screening to reduce the morbidity and mortality from colorectal cancer. Copyright: © Singapore Medical Association.

  3. Colorectal cancer screening

    Directory of Open Access Journals (Sweden)

    Almeida Frederico Ferreira Novaes de

    2000-01-01

    Full Text Available Colorectal cancer (CRC is the third most common cancer in the world, and mortality has remained the same for the past 50 years, despite advances in diagnosis and treatment. Because significant numbers of patients present with advanced or incurable stages, patients with pre-malignant lesions (adenomatous polyps that occur as result of genetic inheritance or age should be screened, and patients with long-standing inflammatory bowel disease should undergo surveillance. There are different risk groups for CRC, as well as different screening strategies. It remains to be determined which screening protocol is the most cost-effective for each risk catagory. The objective of screening is to reduce morbidity and mortality in a target population. The purpose of this review is to analyze the results of the published CRC screening studies, with regard to the measured reduction of morbidity and mortality, due to CRC in the studied populations, following various screening procedures. The main screening techniques, used in combination or alone, include fecal occult blood tests, flexible sigmoidoscopy, and colonoscopy. Evidence from the published literature on screening methods for specific risk groups is scanty and frequently does not arise from controlled studies. Nevertheless, data from these studies, combined with recent advances in molecular genetics, certainly lead the way to greater efficacy and lower cost of CRC screening.

  4. ScreenOS Cookbook

    CERN Document Server

    Brunner, Stefan; Delcourt, David

    2008-01-01

    In the only book that completely covers ScreenOS, six key members of Juniper Network's ScreenOS development team help you troubleshoot secure networks using ScreenOS firewall appliances. Over 200 recipes address a wide range of security issues, provide step-by-step solutions, and include discussions of why the recipes work, so you can easily set up and keep ScreenOS systems on track. The easy-to-follow format enables you to find the topic and specific recipe you need right away.

  5. Monitoring madness

    Energy Technology Data Exchange (ETDEWEB)

    Blankinship, S.

    2006-01-15

    High quality continuous emission monitoring capability can be as essential as high quality emission control equipment. Future mercury monitoring and control requirements add to the justification for better CEMS. The article discusses two prominent mercury measurement methods - the cold vapour atomic absorptive spectrometer (CVAAs) and the atomic absorptive spectrometer (AFS). It stresses the importance of maintaining a CEMS. 1 photo.

  6. Mobility Monitor

    DEFF Research Database (Denmark)

    Schæbel, Anne-Lise; Dybbro, Karina Løvendahl; Andersen, Lisbeth Støvring;

    2015-01-01

    Undersøgelse af digital monitorering af plejehjemsbeboeres vendinger under søvn på Fremtidens Plejehjem, Nørresundby......Undersøgelse af digital monitorering af plejehjemsbeboeres vendinger under søvn på Fremtidens Plejehjem, Nørresundby...

  7. Scoliosis Screening in Schools.

    Science.gov (United States)

    New York State Education Dept., Albany. Div. of Pupil Personnel Services.

    The booklet outlines New York state school policy and procedures for screening students for scoliosis, lateral curvature of the spine. It is explained that screening is designed to discover spinal deformities early enough to prevent surgery. Planning aspects, including organizing a planning team for the school district, are discussed. Among…

  8. Screening in multilayer graphene

    NARCIS (Netherlands)

    van Gelderen, R.; Olsen, Richard; de Morais Smith, C.

    2013-01-01

    In this paper, we study the static polarization in ABC-stacked multilayer graphene. Since the density of states diverges for these systems if the number of layers exceeds three, screening effects are expected to be important. In the random phase approximation, screening can be included through the p

  9. Scoliosis Screening in Schools.

    Science.gov (United States)

    New York State Education Dept., Albany. Div. of Pupil Personnel Services.

    The booklet outlines New York state school policy and procedures for screening students for scoliosis, lateral curvature of the spine. It is explained that screening is designed to discover spinal deformities early enough to prevent surgery. Planning aspects, including organizing a planning team for the school district, are discussed. Among…

  10. Colorectal Cancer Screening

    Science.gov (United States)

    ... screening tests have different risks or harms. Screening tests may cause anxiety when you are thinking about or getting ready ... is cancer when there really isn't) can cause anxiety and is usually followed by more tests (such as biopsy ), which also have risks. The ...

  11. Touch screens go optical

    DEFF Research Database (Denmark)

    Hanson, Steen Grüner; Jakobsen, Michael Linde; Pedersen, Henrik Chresten

    2012-01-01

    A simple optical implementation of a touch screen is made possible by disrupting the total internal reflection in a 2D waveguide.......A simple optical implementation of a touch screen is made possible by disrupting the total internal reflection in a 2D waveguide....

  12. Mammography screening in denmark

    DEFF Research Database (Denmark)

    Vejborg, Ilse Merete Munk; Mikkelsen, Ellen Margrethe; Garne, Jens Peter

    2011-01-01

    Mammography screening is offered healthy women, and a high standard on professional and organizational level is mandatory not only in the screening programme but even in the diagnostic work-up and treatment. The main goal is to achieve a substantial reduction in disease specific mortality...

  13. Mammography screening in Denmark

    DEFF Research Database (Denmark)

    Vejborg, Ilse; Mikkelsen, Ellen Margrethe; Garne, Jens Peter

    2011-01-01

    Mammography screening is offered healthy women, and a high standard on professional and organizational level is mandatory not only in the screening programme but even in the diagnostic work-up and treatment. The main goal is to achieve a substantial reduction in disease specific mortality...

  14. EIA screening in Denmark

    DEFF Research Database (Denmark)

    Nielsen, Eskild Holm; Christensen, Per; Kørnøv, Lone

    2005-01-01

    The article points out that EIA screening is effectively a regulatory instrument and it can be a cost-effective instrument with environmental benefits.......The article points out that EIA screening is effectively a regulatory instrument and it can be a cost-effective instrument with environmental benefits....

  15. Investigations of OTR screen surfaces and shapes

    CERN Document Server

    Welsch, C P; Lefèvre, T

    2006-01-01

    Optical transition radiation (OTR) has proven to be a flexible and effective tool for measuring a wide range of beam parameters, in particular the beam divergence and the transverse beam profile. It is today an established and widely used diagnostic method providing linear real-time measurements. Measurements in the CLIC Test Facility (CTF3) showed that the performance of the present profile monitors is limited by the optical acceptance of the imaging system. In this paper, two methods to improve the systems' performance are presented and results from measurements are shown. First, the influence of the surface quality of the OTR screen itself is addressed. Several possible screen materials have been tested to which different surface treatment techniques were applied. Results from the measured optical characteristics are given. Second, a parabolic-shaped screen support was investigated with the aim of providing an initial focusing of the emitted radiation and thus to reduce the problem of aperture limitation.

  16. Screening for abdominalt aortaaneurisme

    DEFF Research Database (Denmark)

    Lindholt, J S; Juul, Svend; Henneberg, E W

    1997-01-01

    In spite of increasing number of elective resections of abdominal aortic aneurysms (AAA) the mortality or ruptured AAA is increasing. The advantages of elective operations are obvious; the lethality is 2-6% while the lethality of ruptured AAA is 75-95%. However, AAA seldom causes symptoms before...... rupture. Ultrasonographic screening for AAA takes 10 minutes per scan, and the sensitivity and specificity are high. Ultrasonographic screening for AAA is a reliable, safe and inexpensive method for screening, and screening for AAA is discussed worldwide. One point four percent of deaths among men from 65...... to 80 year of age are caused by ruptured AAA. Screening men over 65 for AAA can theoretically prevent a substantial number of deaths. Our calculations predict one prevented AAA-death per 200-300 scans for a cost of about 4000 DKK per saved year of life. However, cost-benefit analyses are based...

  17. LABORATORY MODELS FOR SCREENING ANALGESICS

    Directory of Open Access Journals (Sweden)

    Parle Milind

    2013-01-01

    Full Text Available Pain is a complex unpleasant phenomenon composed of sensory experiences that include time, space, intensity, emotion, cognition and motivation. Analgesics are the agents, which selectively relieve pain by acting in the CNS or by peripheral pain mechanisms without significantly altering consciousness. Analgesics may be narcotic or non-narcotic. The study of pain in animals raises ethical, philosophical and technical problems. Philosophically, there is a problem that pain cannot be monitored directly in animals but can only be measured by examining their responses to nociceptive stimuli. The observed reactions are almost always motor responses ranging from spinal reflexes to complex behavior. The animal models employed for screening of analgesic agents, include Pain-state models based on the use of thermal stimuli, mechanical stimuli, electrical stimuli and chemical stimuli. The neuronal basis of most of the above laboratory models is poorly understood, however their application is profitable in predicting analgesic activity of newly discovered substances.

  18. Barriers to cancer screening.

    Science.gov (United States)

    Womeodu, R J; Bailey, J E

    1996-01-01

    Many barriers to cancer screening have been summarized and discussed. Barriers have been documented in all patient populations, but some groups such as ethnic minorities and the elderly face unique barriers. The barriers to cancer screening, are multifactorial, but much of the responsibility for change must lie with health care providers and the health care delivery industry. This is not to free the patient of all responsibility, but some significant barriers are beyond their direct control. Take, for example, socioeconomic status, disease knowledge, and culturally related perceptions and myths about cancer detection and treatment. The health care industry must do a better job identifying and overcoming these barriers. The significant effects of provider counseling and advice must not be underestimated. Patients must first be advised, and then further actions must be taken if they reject the screening advice. Did they refuse adherence to recommendations because they do not view themselves as susceptible, because of overwhelming personal barriers, or because of a fatalistic attitude toward cancer detection and treatment? If that is the case, physicians and health care institutions must attempt to change perceptions, educate, and personalize the message so that patients accept their disease susceptibility [table: see text]. Multiple patient and provider risk factors have been identified that can be used to target patients particularly at high risk for inadequate cancer screening and providers at high risk for performing inadequate screening. Research has clearly demonstrated the effectiveness of interventions to improve tracking of patient and physician compliance with screening recommendations. Further research is needed to show the impact of managed-care penetration and payer status on screening efforts, and incentive schemes need to be tested that reward institutions and third-party payers who develop uniform standards and procedures for cancer screening. The

  19. Breast Cancer Screening in an Era of Personalized Regimens

    Science.gov (United States)

    Onega, Tracy; Beaber, Elisabeth F.; Sprague, Brian L.; Barlow, William E.; Haas, Jennifer S.; Tosteson, Anna N.A.; Schnall, Mitchell D.; Armstrong, Katrina; Schapira, Marilyn M.; Geller, Berta; Weaver, Donald L.; Conant, Emily F.

    2014-01-01

    Breast cancer screening holds a prominent place in public health, health care delivery, policy, and women’s health care decisions. Several factors are driving shifts in how population-based breast cancer screening is approached, including advanced imaging technologies, health system performance measures, health care reform, concern for “overdiagnosis,” and improved understanding of risk. Maximizing benefits while minimizing the harms of screening requires moving from a “1-size-fits-all” guideline paradigm to more personalized strategies. A refined conceptual model for breast cancer screening is needed to align women’s risks and preferences with screening regimens. A conceptual model of personalized breast cancer screening is presented herein that emphasizes key domains and transitions throughout the screening process, as well as multilevel perspectives. The key domains of screening awareness, detection, diagnosis, and treatment and survivorship are conceptualized to function at the level of the patient, provider, facility, health care system, and population/policy arena. Personalized breast cancer screening can be assessed across these domains with both process and outcome measures. Identifying, evaluating, and monitoring process measures in screening is a focus of a National Cancer Institute initiative entitled PROSPR (Population-based Research Optimizing Screening through Personalized Regimens), which will provide generalizable evidence for a risk-based model of breast cancer screening, The model presented builds on prior breast cancer screening models and may serve to identify new measures to optimize benefits-to-harms tradeoffs in population-based screening, which is a timely goal in the era of health care reform. PMID:24830599

  20. Monarch Monitoring

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — The US Fish and Wildlife Service has engaged in a multi-partnered, integrated strategy for monitoring conservation of the monarch butterfly (Danaus plexippus...

  1. Monitoring Hadoop

    CERN Document Server

    Singh, Gurmukh

    2015-01-01

    This book is useful for Hadoop administrators who need to learn how to monitor and diagnose their clusters. Also, the book will prove useful for new users of the technology, as the language used is simple and easy to grasp.

  2. Recombination monitor

    Energy Technology Data Exchange (ETDEWEB)

    Zhang, S. Y. [Brookhaven National Lab. (BNL), Upton, NY (United States); Blaskiewicz, M. [Brookhaven National Lab. (BNL), Upton, NY (United States)

    2017-02-03

    This is a brief report on LEReC recombination monitor design considerations. The recombination produced Au78+ ion rate is reviewed. Based on this two designs are discussed. One is to use the large dispersion lattice. It is shown that even with the large separation of the Au78+ beam from the Au79+ beam, the continued monitoring of the recombination is not possible. Accumulation of Au78+ ions is needed, plus collimation of the Au79+ beam. In another design, it is shown that the recombination monitor can be built based on the proposed scheme with the nominal lattice. From machine operation point of view, this design is preferable. Finally, possible studies and the alternative strategies with the basic goal of the monitor are discussed.

  3. Colorectal cancer screening awareness among physicians in Greece

    Directory of Open Access Journals (Sweden)

    Chatzimichalis Georgios

    2006-06-01

    Full Text Available Abstract Background Data comparison between SEER and EUROCARE database provided evidence that colorectal cancer survival in USA is higher than in European countries. Since adjustment for stage at diagnosis markedly reduces the survival differences, a screening bias was hypothesized. Considering the important role of primary care in screening activities, the purpose of the study was to investigate the colorectal cancer screening awareness among Hellenic physicians. Methods 211 primary care physicians were surveyed by mean of a self-reported prescription-habits questionnaire. Both physicians' colorectal cancer screening behaviors and colorectal cancer screening recommendations during usual check-up visits were analyzed. Results Only 50% of physicians were found to recommend screening for colorectal cancer during usual check-up visits, and only 25% prescribed cost-effective procedures. The percentage of physicians recommending stool occult blood test and sigmoidoscopy was 24% and 4% respectively. Only 48% and 23% of physicians recognized a cancer screening value for stool occult blood test and sigmoidoscopy. Colorectal screening recommendations were statistically lower among physicians aged 30 or less (p = 0.012. No differences were found when gender, level and type of specialization were analyzed, even though specialists in general practice showed a trend for better prescription (p = 0.054. Conclusion Contemporary recommendations for colorectal cancer screening are not followed by implementation in primary care setting. Education on presymptomatic control and screening practice monitoring are required if primary care is to make a major impact on colorectal cancer mortality.

  4. Bayesian Monitoring.

    OpenAIRE

    Kirstein, Roland

    2005-01-01

    This paper presents a modification of the inspection game: The ?Bayesian Monitoring? model rests on the assumption that judges are interested in enforcing compliant behavior and making correct decisions. They may base their judgements on an informative but imperfect signal which can be generated costlessly. In the original inspection game, monitoring is costly and generates a perfectly informative signal. While the inspection game has only one mixed strategy equilibrium, three Perfect Bayesia...

  5. High-throughput crystallization screening.

    Science.gov (United States)

    Skarina, Tatiana; Xu, Xiaohui; Evdokimova, Elena; Savchenko, Alexei

    2014-01-01

    Protein structure determination by X-ray crystallography is dependent on obtaining a single protein crystal suitable for diffraction data collection. Due to this requirement, protein crystallization represents a key step in protein structure determination. The conditions for protein crystallization have to be determined empirically for each protein, making this step also a bottleneck in the structure determination process. Typical protein crystallization practice involves parallel setup and monitoring of a considerable number of individual protein crystallization experiments (also called crystallization trials). In these trials the aliquots of purified protein are mixed with a range of solutions composed of a precipitating agent, buffer, and sometimes an additive that have been previously successful in prompting protein crystallization. The individual chemical conditions in which a particular protein shows signs of crystallization are used as a starting point for further crystallization experiments. The goal is optimizing the formation of individual protein crystals of sufficient size and quality to make them suitable for diffraction data collection. Thus the composition of the primary crystallization screen is critical for successful crystallization.Systematic analysis of crystallization experiments carried out on several hundred proteins as part of large-scale structural genomics efforts allowed the optimization of the protein crystallization protocol and identification of a minimal set of 96 crystallization solutions (the "TRAP" screen) that, in our experience, led to crystallization of the maximum number of proteins.

  6. Screening for cervical cancer: when theory meets reality

    Directory of Open Access Journals (Sweden)

    Nygård Mari

    2011-06-01

    Full Text Available Abstract Cervical cancer screening reduces morbidity and mortality due to cervical cancer. However, there are many factors that determine the success of any cervical cancer prevention effort: the prevalence of human papillomavirus infection in general population, the existence of an organized screening program and the corresponding coverage, the existence and quality of the field and laboratory facilities for screening and diagnostic follow-up, and the facilities available for treating diagnosed lesions. Monitoring the patient path or "chain of action" for each patient with an abnormal screening result is of crucial importance. Cost-effectiveness models are widely used by decision-makers to determine which cervical cancer screening program would maximize health benefits within a given, usually limited, set of resources. Regardless of their level of sophistication, however, these models cannot replace empirical evaluations of the effectiveness of screening programs. Cervical cancer prevention activities need to be monitored and evaluated in each country where they are introduced to see that they meet performance standards. Policy-makers responsible for allocating resources for cervical cancer prevention have a duty to allocate resources not only for cervical cancer screening, but also for screening program surveillance.

  7. Colorectal cancer screening

    Institute of Scientific and Technical Information of China (English)

    Ramona M McLoughlin; Colm A O'Morain

    2006-01-01

    Colorectal cancer is a major public health burden worldwide.There is clear-cut evidence that screening will reduce colorectal cancer mortality and the only contentious issue is which screening tool to use.Most evidence points towards screening with fecal occult blood testing.The immunochemical fecal occult blood tests have a higher sensitivity than the guaiac-based tests.In addition,their automation and haemoglobin quantification allows a threshold for colonoscopy to be selected that can be accommodated within individual health care systems.

  8. Screening for asbestbetingede sygdomme?

    DEFF Research Database (Denmark)

    Brauer, Charlotte; Baandrup, Ulrik; Jacobsen, Peter

    2009-01-01

    Screening programs for early detection of asbestos-related cancer have been considered. Conventional X-ray, computed tomography of the thorax, and the biomarkers osteopontin and mesothelin have been critically reviewed in the literature, together with survival data from screening programs...... in asbestos-exposed populations. Data do not currently support implementation of screening programs for asbestos-exposed persons in Denmark. Since mesothelioma is most often an occupational disease, these patients should be admitted to an occupational clinic for aetiological evaluation. Udgivelsesdato: 2009...

  9. Screening for Pancreatic Cancer.

    Science.gov (United States)

    Wada, Keita; Takaori, Kyoichi; Traverso, L William

    2015-10-01

    Neither extended surgery nor extended indication for surgery has improved survival in patients with pancreatic cancer. According to autopsy studies, presumably 90% are metastatic. The only cure is complete removal of the tumor at an early stage before it becomes a systemic disease or becomes invasive. Early detection and screening of individuals at risk is currently under way. This article reviews the evidence and methods for screening, either familial or sporadic. Indication for early-stage surgery and precursors are discussed. Surgeons should be familiar with screening because it may provide patients with a chance for cure by surgical resection.

  10. Linking International Cancer Screening Efforts

    Science.gov (United States)

    Drs. Sudha Sivaram and Steve Taplin speak at the International Cancer Screening Network (ICSN) Meeting, which brings together individuals involved in cancer screening research and cancer screening programs from the ICSN’s member countries.

  11. Cervical cancer - screening and prevention

    Science.gov (United States)

    Cancer cervix - screening; HPV - cervical cancer screening; Dysplasia - cervical cancer screening; Cervical cancer - HPV vaccine ... Almost all cervical cancers are caused by HPV (human papilloma virus). HPV is a common virus that spreads through sexual contact. Certain ...

  12. Screening and diagnosis for HIV

    Science.gov (United States)

    HIV testing; HIV screening; HIV screening test; HIV confirmatory test ... Task Force. Final Update Summary: Human Immunodeficiency Virus (HIV) Infection: Screening. July 2015. www.uspreventiveservicestaskforce.org/Page/Document/UpdateSummaryFinal/ ...

  13. Risks of Lung Cancer Screening

    Science.gov (United States)

    ... Treatment Lung Cancer Prevention Lung Cancer Screening Research Lung Cancer Screening (PDQ®)–Patient Version What is screening? Go ... These are called diagnostic tests . General Information About Lung Cancer Key Points Lung cancer is a disease in ...

  14. Smartphone Homecare Monitoring of Hearts

    Directory of Open Access Journals (Sweden)

    Harold Szu

    2013-01-01

    Full Text Available Homecare monitoring blood pressures and heartbeats are commercially available using dedicated devices, for example, wrist watch, pulse oximetry. With the advent of Smartphone and compressive sensing technology, we wish to monitor precisely the electrical waveforms of heartbeats called the electrocardiography (ECG for an aging global villager biomedical wellness homecare system. Our design separates into 3 innovative modules within the size-weight and power-cost bandwidth (Swap-CB limitation. We develop each separately but in concert with one another: (i Smart Electrode (adopting a low-power-mixed signal embedded with modern compressive sensing firmware and applying the nanotechnology to improve the electrodes’ contact impedance as well as novel transduction mechanism, between ECG and electronics, e.g., a pressure mattress coupling, or fiber-optics coupling; (ii Learnable Database (utilizing adaptive wavelets transforms for systolic and diastolic P-QRS-T-U features extraction Aided Target Recognition and adopting Sequential Query Language for a relational database allowing distant monitoring and retrievable; (iii Smartphone (inheriting a large touch screen interface display with powerful computation capability and assisting caretaker reporting system with GPS and ID and two-way interaction with patient panic button for programmable emergence reporting procedure. While (i is novel, (ii and (iii are mature. Together, they can eventually provide a supplementary home screening system for the post- or the prediagnosis care at home with a built-in database searchable with the time, the place, and the degree of urgency happened, using in situ screening.

  15. Neonatal cystic fibrosis screening test

    Science.gov (United States)

    Cystic fibrosis screening - neonatal; Immunoreactive trypsinogen; IRT test; CF - screening ... Cystic fibrosis is a disease passed down through families. CF causes thick, sticky mucus to build up in ...

  16. Barriers to screening mammography.

    Science.gov (United States)

    Sarma, Elizabeth A

    2015-01-01

    Breast cancer (BRCA) is the second most commonly diagnosed cancer among women in the USA, and mammography is an effective means for the early detection of BRCA. Identifying the barriers to screening mammography can inform research, policy and practice aiming to increase mammography adherence. A literature review was conducted to determine common barriers to screening mammography adherence. PsycINFO and PubMed databases were searched to identify studies published between 2000 and 2012 that examined barriers associated with reduced mammography adherence. Three thematic groups of barriers, based on social ecology, were identified from the literature: healthcare system-level, social and individual-level barriers. Researchers must consider screening behaviour in context and, therefore, should simultaneously consider each level of barriers when attempting to understand screening behaviour and create interventions to increase mammography adherence.

  17. Urine drug screen

    Science.gov (United States)

    Drug screen -- urine ... detect the presence of illegal and some prescription drugs in your urine. Their presence indicates that you recently used these drugs. Some drugs may remain in your system for ...

  18. Cervical Cancer Screening

    Science.gov (United States)

    ... are at increased risk for HPV infections. Other risk factors for cervical cancer include: Giving birth to many children. Smoking cigarettes. Using oral contraceptives ("the Pill"). Having a weakened immune system . Cervical Cancer Screening ...

  19. Rapid Lead Screening Test

    Science.gov (United States)

    ... Vitro Diagnostics Tests Used In Clinical Care Rapid Lead Screening Test Share Tweet Linkedin Pin it More ... reducing the need for a follow-up visit. Lead Risk Links Centers for Disease Control and Prevention ( ...

  20. Congenital hypothyroidism: Screening dilemma

    Directory of Open Access Journals (Sweden)

    Meena P Desai

    2012-01-01

    Full Text Available Primary sporadic congenital hypothyroidism (CH is the most common cause of hypothyroidism infancy early childhood in iodine sufficient region. Screening for neonatal CH began in 1970s. The rationale and reason for neonatal screening for CH (NSCH are well established. It is mandatory in most developed countries along with the screen for metabolic disorder. The possibility of measuring TSH and thyroid hormones in cord blood paved the way for newborn screening (NS for CH. Worldwide it is estimated that 25% of the live born population of 130 million babies undergo NSCH. Klein et al., by 1972 had shown improved CNS prognosis in CH treated by age 3 months. NSCH has largely eradicated the severe irreversible neurodevelopmental damage and reversed the chances of growth failure in infancy and early childhood.

  1. Preconception Carrier Screening

    Science.gov (United States)

    ... and Gaucher disease. People of African, Mediterranean, and Southeast Asian heritage should be offered screening for thalassemias ... Publications Committee Opinions Practice Bulletins Patient Education Green Journal Clinical Updates Practice Management Coding Health Info Technology ...

  2. Prenatal Genetic Screening Tests

    Science.gov (United States)

    ... cells from the fetus or placenta obtained through amniocentesis or chorionic villus sampling (CVS) . FAQ164 “Prenatal Genetic ... should be followed by a diagnostic test with amniocentesis or CVS. The cell-free DNA screening test ...

  3. Pancreatic Cancer Screening.

    Science.gov (United States)

    Das, Koushik K; Early, Dayna

    2017-09-06

    This review describes the rationale for pancreatic cancer screening, outlines groups that are at elevated risk for pancreatic cancer, and summarizes the relative risk in each setting. We also review the methods available for performing pancreatic cancer screening and the recommended screening intervals. Several genetic mutations have been identified that increase the risk for pancreatic cancer. Most are rare, however, and at-risk individuals are most often those with a strong family history of pancreatic cancer (with multiple family members affected) but no identifiable genetic mutation. Known genetic syndromes that increase the risk for pancreatic cancer include hereditary pancreatitis, familial atypical mole and multiple melanoma, Peutz-Jeghers syndrome, Lynch syndrome, BRCA mutations, and Li-Fraumeni syndrome. Genetic testing should be performed in conjunction with genetic counseling, and testing of an affected family member is preferred if possible.The goal of pancreatic cancer screening is to identify pancreatic cancer at an early, curable stage or, ideally, to identify precancerous lesions that can be resected to prevent the development of cancer. Imaging can be performed with either endoscopic ultrasound (EUS) or magnetic resonance cholangiopancreatography (MRCP). These techniques are generally considered to be complementary, although an advantage of EUS is that cysts or solid lesions can be sampled at the time of the procedure. Published results of small cohorts of high-risk patients in pancreatic cancer screening programs have demonstrated a high prevalence of small cystic lesions identified on EUS or MRCP, which often represent side-branch intraductal papillary mucinous neoplasms (IPMN). Knowledge of conditions and syndromes that increase pancreatic cancer risk allows one to identify those patients that may benefit from pancreatic cancer screening. As we gather evidence from large, international, multicenter cohorts of patients at high-risk for pancreatic

  4. Virtual screening against obesity.

    Science.gov (United States)

    Markt, P; Herdlinger, S; Schuster, D

    2011-01-01

    The development of novel drugs against obesity is one of the top priorities of worldwide drug research. In recent years, it has been facilitated by the application of virtual screening methods. In this review, we give a short introduction into obesity-related protein targets and computer-aided drug design techniques. Furthermore, we highlight the most successful virtual screening studies, outline their results, and provide suggestions for future anti-obesity drug development.

  5. Aircrew Screening Instruments Review

    Science.gov (United States)

    2007-09-01

    available tools . Several vendors indicated that they will have new selection instruments available within a few months. These are not listed. As noted...AFCAPS-FR-2011-0012 AIRCREW SCREENING INSTRUMENTS REVIEW Diane L. Damos Damos Aviation Services, Inc...June 2007 – August 2007 4. TITLE AND SUBTITLE Aircrew Screening Instruments Review 5a. CONTRACT NUMBER FA3089-06-F-0385 5b. GRANT NUMBER 5c

  6. Monitoring of trace organic air pollutants – a developing country perspective

    CSIR Research Space (South Africa)

    Forbes, PBC

    2008-09-01

    Full Text Available for domestic heating and cooking purposes in developing countries. This paper focuses on the current status of organic air pollutant monitoring in southern Africa, and discusses developments in this regard. Screening methods and monitoring of indicator...

  7. Screening efficiency and screen length of a linear vibrating screen using DEM 3D simulation

    Institute of Scientific and Technical Information of China (English)

    Wang Guifeng; Tong Xin

    2011-01-01

    The effect of screen length on the screening efficiency of particles is studied under various single parameter conditions including frequency,amplitude,vibration angle,and screen inclination.The Discrete Element Method (DEM) has been used to simulate the screening process.A functional relationship between screening efficiency and screen length is established.It is shown that screening efficiency and screen length have a complicated exponential relationship.Relationships between them are profoundly discussed and conclusions are easily drawn:low values of the parameters do not benefit screening; screening efficiency generally increases with screen length; screening efficiency reaches a plateau when these parameters are in range frequently encountered in practical applications.

  8. Lung cancer screening: Update

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Hyea Young [Dept. of Radiology, Center for Lung Cancer, National Cancer Center, Goyang (Korea, Republic of)

    2015-09-15

    Lung cancer is the leading cause of cancer deaths worldwide as well as in Korea. A recent National Lung Screening Trial in U.S. revealed that low-dose CT (LDCT) screening reduced lung cancer specific mortality by 20% in high risk individuals as compared to chest radiograph screening. Based on this evidence, several expert societies in U.S. and Korean multisociety collaborative committee developed guidelines for recommendation of lung cancer screening using annual LDCT in high risk populations. In most of the societies high risk groups are defined as persons aged 55 to 74 years, who are current smokers with history of smoking of more than 30 packs per year or ex-smokers, who quit smoking up to 15 or more years ago. The benefits of LDCT screening are modestly higher than the harms in high risk individuals. The harms included a high rate of false-positive findings, over-diagnosis and radiation-related deaths. Invasive diagnostic procedure due to false positive findings may lead to complications. LDCT should be performed in qualified hospitals and interpreted by expert radiologists. Recently, the American College of Radiology released the current version of Lung cancer CT screening Reporting and Data Systems. Education and actions to stop smoking must be offered to current smokers.

  9. Smartphone hearing screening with integrated quality control and data management.

    Science.gov (United States)

    Swanepoel, De Wet; Myburgh, Hermanus C; Howe, David M; Mahomed, Faheema; Eikelboom, Robert H

    2014-12-01

    To determine if a smartphone application could be used as a calibrated screening audiometer with real-time noise monitoring for school screening using automated test sequences. The investigation comprised three studies. Study 1 evaluated calibration accuracy across four Samsung S5301 smartphones (Android v4.0.4) using commercial Sennheiser HD202 headphones. Study 2 involved referencing smartphone microphone sensitivity to narrowband noise intensity as measured in octave bands by a sound-level meter between 30 and 75 dB SPL (5 dB increments). Study 3 compared screening outcomes of smartphone based and conventional hearing screening. Study 2: 15 normal-hearing subjects (age range, 18-22 years; all female). Study 3: 162 children (324 ears) aged 5 to 7 years. Smartphone calibration at 20, 30, and 40 dB was within 1 dB of recommended reference equivalent thresholds levels. Microphone calibration for noise monitoring had maximum variability across phones of 0.9, 0.6, and 2.9 dB at 1, 2, and 4 kHz, respectively, from reference intensities (30 to 75 dB SPL). Screening outcomes demonstrated no significant difference between smartphone and conventional audiometry with an overall referral rate of 4.3% and 3.7%, respectively. The newly developed smartphone application can be accurately calibrated for audiometry with valid real-time noise monitoring, and clinical results are comparable to conventional screening.

  10. [Organized breast cancer screening].

    Science.gov (United States)

    Rouëssé, Jacques; Sancho-Garnier, Hélèn

    2014-02-01

    Breast screening programs are increasingly controversial, especially regarding two points: the number of breast cancer deaths they avoid, and the problem of over-diagnosis and over-treatment. The French national breast cancer screening program was extended to cover the whole country in 2004. Ten years later it is time to examine the risk/benefit ratio of this program and to discuss the need for change. Like all forms of cancer management, screening must be regularly updated, taking into account the state of the art, new evidence, and uncertainties. All screening providers should keep themselves informed of the latest findings. In the French program, women aged 50-74 with no major individual or familial risk factors for breast cancer are offered screening mammography and clinical breast examination every two years. Images considered non suspicious of malignancy by a first reader are re-examined by a second reader. The devices and procedures are subjected to quality controls. Participating radiologists (both public and private) are required to read at least 500 mammographies per year. The program's national participation rate was 52.7 % in 2012. When individual screening outside of the national program is taken into account (nearly 15 % of women), coverage appears close to the European recommendation of 65 %. Breast cancer mortality has been falling in France by 0.6 % per year for over 30 years, starting before mass screening was implemented, and by 1.5 % since 2005. This decline can be attributed in part to earlier diagnosis and better treatment, so that the specific impact of screening cannot easily be measured. Over-treatment, defined as the detection and treatment of low-malignancy tumors that would otherwise not have been detected in a person's lifetime, is a major negative effect of screening, but its frequency is not precisely known (reported to range from 1 % to 30 %). In view of these uncertainties, it would be advisable to modify the program in order to

  11. [Development of physiological monitors based on the Zigbee technology for hyperbaric oxygen chambers].

    Science.gov (United States)

    Zheng, Jin-Nuan; Wu, Bao-Ming; Lin, Jin-Zhao; Wang, Qiang

    2008-05-01

    This paper introduces a monitor that can monitor five physiological parameters (ECG, blood pressure, spo2, respiration and temperature) based on Wireless Sensor Networks. The monitor will be applied to hyperbaric oxygen chambers. After acquisition, the signal will be displayed on the LCD screen of the monitor terminal in the cabin. At the same time, the Zigbee RF module will send the signal to the extravehicular guardianship PC terminals. This monitor equipment can realize synchronous real-time monitoring both inside and outside. What's more? A host can also display monitoring data the three monitor terminals collected. Preliminary clinical tests show that the monitors are safe and the monitoring results are satisfactory.

  12. Pattern Visual Evoked Potentials Elicited by Organic Electroluminescence Screen

    Directory of Open Access Journals (Sweden)

    Celso Soiti Matsumoto

    2014-01-01

    Full Text Available Purpose. To determine whether organic electroluminescence (OLED screens can be used as visual stimulators to elicit pattern-reversal visual evoked potentials (p-VEPs. Method. Checkerboard patterns were generated on a conventional cathode-ray tube (S710, Compaq Computer Co., USA screen and on an OLED (17 inches, 320 × 230 mm, PVM-1741, Sony, Tokyo, Japan screen. The time course of the luminance changes of each monitor was measured with a photodiode. The p-VEPs elicited by these two screens were recorded from 15 eyes of 9 healthy volunteers (22.0 ± 0.8 years. Results. The OLED screen had a constant time delay from the onset of the trigger signal to the start of the luminescence change. The delay during the reversal phase from black to white for the pattern was 1.0 msec on the cathode-ray tube (CRT screen and 0.5 msec on the OLED screen. No significant differences in the amplitudes of P100 and the implicit times of N75 and P100 were observed in the p-VEPs elicited by the CRT and the OLED screens. Conclusion. The OLED screen can be used as a visual stimulator to elicit p-VEPs; however the time delay and the specific properties in the luminance change must be taken into account.

  13. Herbicide resistance screening assay.

    Science.gov (United States)

    Peterson, Joan M

    2009-01-01

    Herbicide resistance screening is a method that can be used not only to determine presence of the enzyme, phosphinothricin acetyltransferase, encoded by either the Bar or the Pat gene in transgenic maize, but also to assess the inheritance ratio of those genes in a segregating population. Herbicide screening can also be used to study linkage of a transgene of interest that was cotransformed with the herbicide resistance marker gene. By combining the herbicide screen assay with a PCR-based screen of leaf tissue DNA for the presence of both the Bar or the Pat gene marker and a cotransformed transgene of interest from the same seedling tissue and maintaining that seedling identity, the researcher can identify linkage or the possible breakdown in linkage of the marker gene and the transgene of interest. Further, the occurrence of "DNA silencing" can be evaluated if an individual seedling that was susceptible to the applied herbicide nonetheless gave PCR data that indicated presence of the gene responsible for herbicide resistance. Similarly, "DNA silencing" of the gene of interest may be investigated if the seeds can be screened and scored for that phenotypic trait in a nondestructive manner prior to planting.

  14. Screening for human papillomavirus: Is urine useful?

    Directory of Open Access Journals (Sweden)

    D′Hauwers K

    2009-01-01

    Full Text Available Persistent infection with high-risk Human papillomavirus (hr-HPV 16, 18, 31, 33, and 45 is the main risk factor for developing malignant genital lesions. Screening methods and follow-up schedules for cervical cancer are well known. A golden standard to screen and monitor men does not exist yet, because HPV-related, life threatening malignancies in men are rare. The importance of male HPV screening lies mainly in HPV vaccination. Young females are the target group for HPV, but men are considered to be the reservoir for HPV and to have a role in the perpetuation of the infection in the general population. We looked at the usefulness of urine as a tool for HPV screening. Pubmed was searched with the words ′′HPV′′, ′′Urine,′′ and ′′HPV-DNA′′. The chance of finding HPV-DNA in urine is higher in men with lesions in the urethra than outside the urethra, and in women with abnormal cervical cytology. In general, the results of testing urine for HPV-DNA are better for women than for men, probably because of the anatomical position of the urethra to the vagina, vulva, and cervix. In both genders, urine HPV prevalence is higher in HIV pos patients and in high-risk populations. Urine, to screen asymptomatic low-risk-profile (women seems less useful because their urine samples are often inadequate. If urine proves to be the best medium to screen, a low-risk population remains controversial.

  15. Short apraxia screening test.

    Science.gov (United States)

    Leiguarda, Ramon; Clarens, Florencia; Amengual, Alejandra; Drucaroff, Lucas; Hallett, Mark

    2014-01-01

    Limb apraxia comprises many different and common disorders, which are largely unrecognized essentially because there is no easy-to-use screening test sensitive enough to identify all types of limb praxis deficits. We evaluated 70 right-handed patients with limb apraxia due to a single focal lesion of the left hemisphere and 40 normal controls, using a new apraxia screening test. The test covered 12 items including: intransitive gestures, transitive gestures elicited under verbal, visual, and tactile modalities, imitation of meaningful and meaningless postures and movements, and a multiple object test. Interrater reliability was maximum for a cutoff of >2 positive items identifying apraxia on the short battery (Cohen's kappa .918, p 3 items (Cohen's kappa .768, p 2 was higher, indicating greater apraxia diagnosis agreement between raters at this cutoff value. The screening test proved to have high specificity and sensitivity to diagnose every type of upper limb praxis deficit, thus showing advantages over previously published tests.

  16. Allergic sensitization: screening methods

    DEFF Research Database (Denmark)

    Ladics, Gregory S.; Fry, Jeremy; Goodman, Richard

    2014-01-01

    Experimental in silico, in vitro, and rodent models for screening and predicting protein sensitizing potential are discussed, including whether there is evidence of new sensitizations and allergies since the introduction of genetically modified crops in 1996, the importance of linear versus...... of infection; (f) role of the gut microbiota; (g) influence of the structure and physicochemical properties of the protein; and (h) the genetic background and physiology of consumers. The consensus view is that sensitization screening models are not yet validated to definitively predict the de novo sensitizing...

  17. Energy Monitoring

    DEFF Research Database (Denmark)

    Hansen, Claus T.; Madsen, Dines; Christiensen, Thomas

    Energy measurement has become an important aspect of our daily lives since we have learned that energy consumption, is one of the main source of global warming. Measuring instruments varies from a simple watt-meter to more sophisticated microprocessor control devices. The negative effects...... that fossil fuels induce on our environment has forced us to research renewable energy such as sunlight, wind etc. This new environmental awareness has also helped us to realize the importance of monitoring and controlling our energy use. The main purpose in this research is to introduce a more sophisticated...... but affordable way to monitor energy consumption of individuals or groups of home appliances. By knowing their consumption the utilization can be regulated for more efficient use. A prototype system has been constructed to demonstrate our idea....

  18. Energy Monitoring

    DEFF Research Database (Denmark)

    Hansen, Claus T.; Madsen, Dines; Christiensen, Thomas

    Energy measurement has become an important aspect of our daily lives since we have learned that energy consumption, is one of the main source of global warming. Measuring instruments varies from a simple watt-meter to more sophisticated microprocessor control devices. The negative effects...... that fossil fuels induce on our environment has forced us to research renewable energy such as sunlight, wind etc. This new environmental awareness has also helped us to realize the importance of monitoring and controlling our energy use. The main purpose in this research is to introduce a more sophisticated...... but affordable way to monitor energy consumption of individuals or groups of home appliances. By knowing their consumption the utilization can be regulated for more efficient use. A prototype system has been constructed to demonstrate our idea....

  19. Material monitoring

    Energy Technology Data Exchange (ETDEWEB)

    Kotter, W.; Zirker, L.; Hancock, J.A.

    1995-11-01

    Waste Reduction Operations Complex (WROC) facilities are located at the Idaho National Engineering Laboratory (INEL). The overall goal for the Pollution Prevention/Waste Minimization Unit is to identify and establish the correct amount of waste generated so that it can be reduced. Quarterly, the INEL Pollution Prevention (P2) Unit compares the projected amount of waste generated per process with the actual amount generated. Examples of waste streams that would be addresses for our facility would include be are not limited to: Maintenance, Upgrades, Office and Scrap Metal. There are three potential sources of this variance: inaccurate identification of those who generate the waste; inaccurate identification of the process that generates the waste; and inaccurate measurement of the actual amount generated. The Materials Monitoring Program was proposed to identify the sources of variance and reduce the variance to an acceptable level. Prior to the implementation of the Material Monitoring Program, all information that was gathered and recorded was done so through an informal estimation of waste generated by various personnel concerned with each processes. Due to the inaccuracy of the prior information gathering system, the Material Monitoring Program was established. The heart of this program consists of two main parts. In the first part potential waste generators provide information on projected waste generation process. In the second part, Maintenance, Office, Scrap Metal and Facility Upgrade wastes from given processes is disposed within the appropriate bin dedicated to that process. The Material Monitoring Program allows for the more accurate gathering of information on the various waste types that are being generated quarterly.

  20. 20:60:20--differences in energy behaviour and conservation between and within households with electricity monitors.

    Directory of Open Access Journals (Sweden)

    Niamh Murtagh

    Full Text Available The introduction of electricity monitors (in-home displays; IHDs, which show accurate and up-to-the-minute energy usage, is expected to lead to reduction in consumption. Studies of feedback on domestic electricity use have generally supported this view. However, such studies also demonstrate wide variation between households. Examining the heterogeneity of responses is essential for understanding the actual and potential effectiveness of IHDs and in order to target interventions effectively. To explore differences between households' responses to IHDs, we conducted a qualitative study with 21 households who had an IHD for more than six months. Of the 21, only four households continued to refer to the IHD and the findings suggest that attempts to reduce energy consumption were situated in wider social and physical contexts. Further, the participants demonstrated energy saving behaviour before and outside of IHD usage. The patterns of energy behaviours and attempts at electricity conservation could best be understood by categorising the households into three types: the Monitor Enthusiasts (20%, the Aspiring Energy Savers (60% and the Energy Non-Engaged (20%. The factors of importance in energy behaviour differed between the categories. Financial savings contributed to efforts to reduce energy use but only up to boundaries which varied considerably between households. Social practices and social relationships appeared to constrain what actions households were prepared to undertake, illuminating aspects of inter-household variation. Within the household, all energy users were not equal and we found that women were particularly influential on energy use through their primary responsibility for domestic labour on behalf of the household. The implications of the findings for environmental campaigning are discussed.

  1. 20:60:20--differences in energy behaviour and conservation between and within households with electricity monitors.

    Science.gov (United States)

    Murtagh, Niamh; Gatersleben, Birgitta; Uzzell, David

    2014-01-01

    The introduction of electricity monitors (in-home displays; IHDs), which show accurate and up-to-the-minute energy usage, is expected to lead to reduction in consumption. Studies of feedback on domestic electricity use have generally supported this view. However, such studies also demonstrate wide variation between households. Examining the heterogeneity of responses is essential for understanding the actual and potential effectiveness of IHDs and in order to target interventions effectively. To explore differences between households' responses to IHDs, we conducted a qualitative study with 21 households who had an IHD for more than six months. Of the 21, only four households continued to refer to the IHD and the findings suggest that attempts to reduce energy consumption were situated in wider social and physical contexts. Further, the participants demonstrated energy saving behaviour before and outside of IHD usage. The patterns of energy behaviours and attempts at electricity conservation could best be understood by categorising the households into three types: the Monitor Enthusiasts (20%), the Aspiring Energy Savers (60%) and the Energy Non-Engaged (20%). The factors of importance in energy behaviour differed between the categories. Financial savings contributed to efforts to reduce energy use but only up to boundaries which varied considerably between households. Social practices and social relationships appeared to constrain what actions households were prepared to undertake, illuminating aspects of inter-household variation. Within the household, all energy users were not equal and we found that women were particularly influential on energy use through their primary responsibility for domestic labour on behalf of the household. The implications of the findings for environmental campaigning are discussed.

  2. 20∶60∶20 - Differences in Energy Behaviour and Conservation between and within Households with Electricity Monitors

    Science.gov (United States)

    Murtagh, Niamh; Gatersleben, Birgitta; Uzzell, David

    2014-01-01

    The introduction of electricity monitors (in-home displays; IHDs), which show accurate and up-to-the-minute energy usage, is expected to lead to reduction in consumption. Studies of feedback on domestic electricity use have generally supported this view. However, such studies also demonstrate wide variation between households. Examining the heterogeneity of responses is essential for understanding the actual and potential effectiveness of IHDs and in order to target interventions effectively. To explore differences between households' responses to IHDs, we conducted a qualitative study with 21 households who had an IHD for more than six months. Of the 21, only four households continued to refer to the IHD and the findings suggest that attempts to reduce energy consumption were situated in wider social and physical contexts. Further, the participants demonstrated energy saving behaviour before and outside of IHD usage. The patterns of energy behaviours and attempts at electricity conservation could best be understood by categorising the households into three types: the Monitor Enthusiasts (20%), the Aspiring Energy Savers (60%) and the Energy Non-Engaged (20%). The factors of importance in energy behaviour differed between the categories. Financial savings contributed to efforts to reduce energy use but only up to boundaries which varied considerably between households. Social practices and social relationships appeared to constrain what actions households were prepared to undertake, illuminating aspects of inter-household variation. Within the household, all energy users were not equal and we found that women were particularly influential on energy use through their primary responsibility for domestic labour on behalf of the household. The implications of the findings for environmental campaigning are discussed. PMID:24642946

  3. Smartphone home monitoring of ECG

    Science.gov (United States)

    Szu, Harold; Hsu, Charles; Moon, Gyu; Landa, Joseph; Nakajima, Hiroshi; Hata, Yutaka

    2012-06-01

    A system of ambulatory, halter, electrocardiography (ECG) monitoring system has already been commercially available for recording and transmitting heartbeats data by the Internet. However, it enjoys the confidence with a reservation and thus a limited market penetration, our system was targeting at aging global villagers having an increasingly biomedical wellness (BMW) homecare needs, not hospital related BMI (biomedical illness). It was designed within SWaP-C (Size, Weight, and Power, Cost) using 3 innovative modules: (i) Smart Electrode (lowpower mixed signal embedded with modern compressive sensing and nanotechnology to improve the electrodes' contact impedance); (ii) Learnable Database (in terms of adaptive wavelets transform QRST feature extraction, Sequential Query Relational database allowing home care monitoring retrievable Aided Target Recognition); (iii) Smartphone (touch screen interface, powerful computation capability, caretaker reporting with GPI, ID, and patient panic button for programmable emergence procedure). It can provide a supplementary home screening system for the post or the pre-diagnosis care at home with a build-in database searchable with the time, the place, and the degree of urgency happened, using in-situ screening.

  4. [Problems in standartization of population fluorographic screening].

    Science.gov (United States)

    Svistunov, V A; Korablev, V N; Svistunova, V P; Boloniaeva, N A; Platonova, V V; Savinykh, T N

    2000-01-01

    The authors have developed the methodology and techniques for standardizing fluorographic screening by using computed technology. The proposed does not require any manually written registration, the accounting of both patient and fluorogram in-and-outflows, the keeping on-going medical documents and paper archives. At the same time the technique allows one to form computerized lists, the dates of patients' visits, to control radiologists' activities, to supervise control over the use of hospital and mobile equipment, to plan expendable materials, etc. The efficiency and novelty of the technology are based on the computerization to make a diagnosis, and to set up a centralized bank of data on patients. This provides favorable conditions for continuous monitoring of fluographic screening of the population at any level of management and administration.

  5. Screening for lung cancer

    DEFF Research Database (Denmark)

    Infante, Maurizio V; Pedersen, Jesper H

    2010-01-01

    In lung cancer screening with low-dose spiral computed tomography (LDCT), the proportion of stage I disease is 50-85%, and the survival rate for resected stage I disease can exceed 90%, but proof of real benefit in terms of lung cancer mortality reduction must come from the several randomized...

  6. Screening for lung cancer

    DEFF Research Database (Denmark)

    Infante, Maurizio V; Pedersen, Jesper H

    2010-01-01

    In lung cancer screening with low-dose spiral computed tomography (LDCT), the proportion of stage I disease is 50-85%, and the survival rate for resected stage I disease can exceed 90%, but proof of real benefit in terms of lung cancer mortality reduction must come from the several randomized...

  7. Afterword: "Screening Schoolhood"

    Science.gov (United States)

    Howard, Jeremy

    2011-01-01

    "Screening schoolhood" attempts to move on both the debate and material covered by the six lead articles in this special issue. It appreciates the ways the articles, and the films they examine, deal with educational issues while at the same time evaluating their range in terms of creative construct and place in the history of documentary film.…

  8. Technology monitoring; Technologie-Monitoring

    Energy Technology Data Exchange (ETDEWEB)

    Eicher, H.; Rigassi, R. [Eicher und Pauli AG, Liestal (Switzerland); Ott, W. [Econcept AG, Zuerich (Switzerland)

    2003-07-01

    This study made for the Swiss Federal Office of Energy (SFOE) examines ways of systematically monitoring energy technology development and the cost of such technologies in order to pave the way to a basis for judging the economic development of new energy technologies. Initial results of a survey of the past development of these technologies are presented and estimates are made of future developments in the areas of motor-based combined heat and power systems, fuel-cell heating units for single-family homes and apartment buildings, air/water heat pumps for new housing projects and high-performance thermal insulation. The methodology used for the monitoring and analysis of the various technologies is described. Tables and diagrams illustrate the present situation and development potential of various fields of technology.

  9. [Ultrasound screening of abdominal aortic aneurysm: Lessons from Vesale 2013].

    Science.gov (United States)

    Laroche, J P; Becker, F; Baud, J M; Miserey, G; Jaussent, A; Picot, M C; Bura-Rivière, A; Quéré, I

    2015-12-01

    Although aneurysm of the abdominal infra-renal aorta (AAA) meets criteria warranting B mode ultrasound screening, the advantages of mass screening versus selective targeted opportunistic screening remain a subject of debate. In France, the French Society of Vascular Medicine (SFMV) and the Health Authority (HAS) published recommendations for targeted opportunistic screening in 2006 and 2013 respectively. The SFMV held a mainstream communication day on November 21, 2013 in France involving participants from metropolitan France and overseas departments that led to a proposal for free AAA ultrasound screening: the Vesalius operation. Being a consumer operation, the selection criteria were limited to age (men and women between 60 and 75 years); the age limit was lowered to 50 years in case of direct family history of AAA. More than 7000 people (as many women as men) were screened in 83 centers with a 1.70% prevalence of AAA in the age-based target population (3.12% for men, 0.27% for women). The median diameter of detected AAA was 33 mm (range 20 to 74 mm). The prevalence of AAA was 1.7% in this population. Vesalius data are consistent with those of the literature both in terms of prevalence and for cardiovascular risk factors with the important role of smoking. Lessons from Vesalius to take into consideration are: screening is warranted in men 60 years and over, especially smokers, and in female smokers. Screening beyond 75 years should be discussed. Given the importance of screening, the SFMV set up a year of national screening for AAA (Vesalius operation 2014/2015) in order to increase public and physician awareness about AAA detection, therapeutic management, and monitoring. AAA is a serious, common, disease that kills 6000 people each year. The goal of screening is cost-effective reduction in the death toll.

  10. Paediatric frontal chest radiograph screening with fine-tuned convolutional neural networks

    CSIR Research Space (South Africa)

    Gerrand, Jonathan D

    2017-07-01

    Full Text Available Within developing countries, there is a realistic need for technologies that can assist medical practitioners in meeting the increasing demand for patient screening and monitoring. To this end, computer aided diagnosis (CAD) based approaches...

  11. Optimising screening for cognitive dysfunction in bipolar disorder: Validation and evaluation of objective and subjective tools

    DEFF Research Database (Denmark)

    Jensen, Johan Høy; Støttrup, Mette Marie; Nayberg, Emilie;

    2015-01-01

    Introduction Cognitive impairment is common in bipolar disorder and contributes to socio-occupational difficulties. The objective was to validate and evaluate instruments to screen for and monitor cognitive impairments, and improve the understanding of the association between cognitive measures...

  12. A Triangulation Method for Identifying Hydrostratigraphic Locations of Well Screens

    Energy Technology Data Exchange (ETDEWEB)

    Whiteside, T. S. [Savannah River Site (SRS), Aiken, SC (United States). Savannah River National Lab. (SRNL). Radiological Performance Assessment

    2015-01-31

    A method to identify the hydrostratigraphic location of well screens was developed using triangulation with known locations. This method was applied to all of the monitor wells being used to develop the new GSA groundwater model. Results from this method are closely aligned with those from an alternate method which uses a mesh surface.

  13. Monitoring microcirculation.

    Science.gov (United States)

    Ocak, Işık; Kara, Atila; Ince, Can

    2016-12-01

    The clinical relevance of microcirculation and its bedside observation started gaining importance in the 1990s since the introduction of hand-held video microscopes. From then, this technology has been continuously developed, and its clinical relevance has been established in more than 400 studies. In this paper, we review the different types of video microscopes, their application techniques, the microcirculation of different organ systems, the analysis methods, and the software and scoring systems. The main focus of this review will be on the state-of-art technique, CytoCam-incident dark-field imaging, and the most recent technological and technical updates concerning microcirculation monitoring.

  14. Apparatus for combinatorial screening of electrochemical materials

    Science.gov (United States)

    A high throughput combinatorial screening method and apparatus for the evaluation of electrochemical materials using a single voltage source is disclosed wherein temperature changes arising from the application of an electrical load to a cell array are used to evaluate the relative electrochemical efficiency of the materials comprising the array. The apparatus may include an array of electrochemical cells that are connected to each other in parallel or in series, an electronic load for applying a voltage or current to the electrochemical cells , and a device , external to the cells, for monitoring the relative temperature of each cell when the load is applied.

    2009-12-15

    A high throughput combinatorial screening method and apparatus for the evaluation of electrochemical materials using a single voltage source (2) is disclosed wherein temperature changes arising from the application of an electrical load to a cell array (1) are used to evaluate the relative electrochemical efficiency of the materials comprising the array. The apparatus may include an array of electrochemical cells (1) that are connected to each other in parallel or in series, an electronic load (2) for applying a voltage or current to the electrochemical cells (1), and a device (3), external to the cells, for monitoring the relative temperature of each cell when the load is applied.

  15. Cardiac event monitors

    Science.gov (United States)

    ... ECG) - ambulatory; Continuous electrocardiograms (EKGs); Holter monitors; Transtelephonic event monitors ... attached. You can carry or wear a cardiac event monitor up to 30 days. You carry the ...

  16. Screening with rubber screen surfaces with variously shaped apertures

    Energy Technology Data Exchange (ETDEWEB)

    Bock, B.; Kraemer, T.

    1984-07-01

    Rubber screen surfaces are advantageous for bulk materials screening because of their low rate of wear and low noise emission and because they tend to prevent clogging. Screens with four different aperture shapes and sizes were available for experimental research. The cut sizes were determined in relation to the above-mentioned parameters with round and with crushed feed materials.

  17. Control systems are General Motors' biggest energy saver

    Energy Technology Data Exchange (ETDEWEB)

    1979-06-01

    In 1978, General Motors Corp. used almost 3% less energy than it did in 1972, even though production had increased about 25%. Most of the savings are the result of improved technology and design changes in buildings, equipment, and processes. Computerized energy management control systems are now in operation or being installed in 78 GM buildings.

  18. A grant for energy savers; Zuschuss fuer Stromsparer

    Energy Technology Data Exchange (ETDEWEB)

    Janzing, Bernward

    2013-03-15

    The competition for power grids as well as gas grids in Stuttgart (Federal Republic of Germany) is undecided. But the newly founded public utility has begun to sell green electricity. At the beginning of March 2012, the public utility Stuttgart put a new photovoltaic plant into operation at the outbuildings of the Porsche Arena and Hanns-Martin-Schleyer Hall. Overall, the public utility Stuttgart want to invest nearly 800 million Euro in renewable energy projects up to the year 2020.

  19. Radiation damage limitations for the Fermilab Energy Doubler/Saver

    Energy Technology Data Exchange (ETDEWEB)

    Sanger, P.A.

    1977-01-01

    One important factor determining the lifetime of particle accelerators using superconducting magnets is the accumulated radiation damage of the magnet components. Using existing damage studies and a measured correlation between the radiation levels with the beam-off and the beam-on, a reasonable assessment of magnet lifetimes can be made. On the basis of this assessment it is expected that damage to the magnet conductor will not limit the magnet performance. The proper choice of polymeric materials used in the magnet is necessary to avoid frequent refurbishing of the magnets.

  20. Evaluation of the Haemonetics V50--time saver protocol.

    Science.gov (United States)

    Soudavar, F; Borberg, H

    1992-10-01

    196 platelet apheresis procedures using the cell separator Haemonetics V 50 were performed applying 8 cycles under varying conditions. The anticoagulant ACD-A was used in a whole-blood to anticoagulant ratio of 8:1. The flow rate was selected for a range of 40-70 ml/min and the centrifuge speed was established at 4,800 and 4,400 rpm. The PWC factor was chosen between 0 and 4. 162 procedures could be statistically evaluated. 34 apheresis were accompanied with technical complications. The mean yield was (4.3 +/- 1.05) x 10(11) platelets, and the average of extraction efficiency (EE) was 53.9 +/- 8.2%. An analysis of variance confirmed that a higher flow rate decreased the EE (p < 0.002) and also the leukocyte counts (p < 0.0005). Increasing the PWC factor led to a higher EE; however, the leukocyte counts of the platelet concentrate were also increased (p < 0.0005). The g force has an essential effect. A high g force of the centrifuge permits to obtain a large quantity of platelets which is combined with a higher leukocyte contamination. Decreasing the centrifuge speed to 4,400 rpm by using PWC factors of 0 and 4 with different flow rates (50 and 60 ml/min) decreased the EE and the leukocyte counts in the product.

  1. Energy Savers: Tips on Saving Money & Energy at Home

    Energy Technology Data Exchange (ETDEWEB)

    None

    2014-05-01

    Provides consumers with home energy and money savings tips such as insulation, weatherization, heating, cooling, water heating, energy efficient windows, landscaping, lighting, and energy efficient appliances.

  2. Energy Savers: Tips on Saving Money & Energy at Home

    Energy Technology Data Exchange (ETDEWEB)

    None

    2011-12-01

    Provides consumers with home energy and money savings tips such as insulation, weatherization, heating, cooling, water heating, energy efficient windows, landscaping, lighting, and energy efficient appliances.

  3. Rotterdam AMBlyopia screening effectiveness study: Detection and causes of amblyopia in a large birth cohort

    NARCIS (Netherlands)

    J.H. Groenewoud (Hanny); A.M. Tjiam (Angela); V.K. Lantau (Kathleen); W.C. Hoogeveen; J.T.H.N. de Faber; R.E. Juttmann (Rikard); H.J. de Koning (Harry); H.J. Simonsz (Huib)

    2010-01-01

    textabstractPurpose. The Dutch population-based child health monitoring program includes regular preverbal (age range, 1-24 months) and preschool (age range, 36-72 months) vision screening. This study is on the contribution of an organized vision screening program to the detection of amblyopia.

  4. Time-resolved luminescence screening method for enrofloxacin in beef serum

    Science.gov (United States)

    Enrofloxacin is one of only two fluoroquinolone antibiotics approved for use in cattle in the U.S. Microbial screening methods currently used in the U.S. for monitoring veterinary drug residues are not sensitive or selective for fluoroquinolones. In this work, a luminescence-based screening assay ...

  5. Terbium-sensitized luminescence screening method for fluoroquinolones in beef serum

    Science.gov (United States)

    Enrofloxacin is one of only two fluoroquinolone antibiotics approved for use in cattle in the U.S. Microbial screening methods commonly used for monitoring veterinary drug residues are not sensitive or selective for fluoroquinolones. In this work, a luminescence-based screening assay was developed...

  6. Reading and Studying on the Screen: An Overview of Literature towards Good Learning Design Practice

    Science.gov (United States)

    Nichols, Mark

    2016-01-01

    As distance education moves increasingly towards online provision, and because of the benefits provided by online approaches, students will be expected to engage with more resources available on screen. Contemporary forms of reading from the screen include reading from tablet devices, LCD monitors, and smartphones. However, print remains the…

  7. Melanoma screening with cellular phones.

    Directory of Open Access Journals (Sweden)

    Cesare Massone

    Full Text Available BACKGROUND: Mobile teledermatology has recently been shown to be suitable for teledermatology despite limitations in image definition in preliminary studies. The unique aspect of mobile teledermatology is that this system represents a filtering or triage system, allowing a sensitive approach for the management of patients with emergent skin diseases. METHODOLOGY/PRINCIPAL FINDINGS: In this study we investigated the feasibility of teleconsultation using a new generation of cellular phones in pigmented skin lesions. 18 patients were selected consecutively in the Pigmented Skin Lesions Clinic of the Department of Dermatology, Medical University of Graz, Graz (Austria. Clinical and dermoscopic images were acquired using a Sony Ericsson with a built-in two-megapixel camera. Two teleconsultants reviewed the images on a specific web application (http://www.dermahandy.net/default.asp where images had been uploaded in JPEG format. Compared to the face-to-face diagnoses, the two teleconsultants obtained a score of correct telediagnoses of 89% and of 91.5% reporting the clinical and dermoscopic images, respectively. CONCLUSIONS/SIGNIFICANCE: The present work is the first study performing mobile teledermoscopy using cellular phones. Mobile teledermatology has the potential to become an easy applicable tool for everyone and a new approach for enhanced self-monitoring for skin cancer screening in the spirit of the eHealth program of the European Commission Information for Society and Media.

  8. Melanoma screening with cellular phones.

    Science.gov (United States)

    Massone, Cesare; Hofmann-Wellenhof, Rainer; Ahlgrimm-Siess, Verena; Gabler, Gerald; Ebner, Christoph; Soyer, H Peter

    2007-05-30

    Mobile teledermatology has recently been shown to be suitable for teledermatology despite limitations in image definition in preliminary studies. The unique aspect of mobile teledermatology is that this system represents a filtering or triage system, allowing a sensitive approach for the management of patients with emergent skin diseases. In this study we investigated the feasibility of teleconsultation using a new generation of cellular phones in pigmented skin lesions. 18 patients were selected consecutively in the Pigmented Skin Lesions Clinic of the Department of Dermatology, Medical University of Graz, Graz (Austria). Clinical and dermoscopic images were acquired using a Sony Ericsson with a built-in two-megapixel camera. Two teleconsultants reviewed the images on a specific web application (http://www.dermahandy.net/default.asp) where images had been uploaded in JPEG format. Compared to the face-to-face diagnoses, the two teleconsultants obtained a score of correct telediagnoses of 89% and of 91.5% reporting the clinical and dermoscopic images, respectively. The present work is the first study performing mobile teledermoscopy using cellular phones. Mobile teledermatology has the potential to become an easy applicable tool for everyone and a new approach for enhanced self-monitoring for skin cancer screening in the spirit of the eHealth program of the European Commission Information for Society and Media.

  9. Medicare Preventive and Screening Services

    Science.gov (United States)

    ... get about Medicare Lost/incorrect Medicare card Report fraud & abuse File a complaint Identity theft: protect yourself ... often is it covered? Medicare Part B (Medical Insurance) covers: Abdominal aortic aneurysm screening Alcohol misuse screenings & ...

  10. National Lung Screening Trial (NLST)

    Science.gov (United States)

    The National Lung Screening Trial (NLST), a research study sponsored by the National Cancer Institute that used low-dose helical CT scans or chest X-ray to screen men and women at risk for lung cancer.

  11. Glucose screening tests during pregnancy

    Science.gov (United States)

    Oral glucose tolerance test - pregnancy; OGTT - pregnancy; Glucose challenge test - pregnancy; Gestational diabetes - glucose screening ... screening test between 24 and 28 weeks of pregnancy. The test may be done earlier if you ...

  12. Developments in Colorectal Cancer Screening

    Science.gov (United States)

    ... JavaScript on. Feature: Colorectal Cancer Developments in Colorectal Cancer Screening Past Issues / Summer 2016 Table of Contents Dr. ... patients know to help determine the best colon cancer screening test for them? Colonoscopy is considered the gold ...

  13. Risks of Endometrial Cancer Screening

    Science.gov (United States)

    ... Transvaginal ultrasound Endometrial sampling Tests are used to screen for different types of cancer. Some screening tests ... endometrium by inserting a brush, curette , or thin, flexible tube through the cervix and into the uterus. ...

  14. Screening for Abdominal Aortic Aneurysm

    Science.gov (United States)

    Understanding Task Force Recommendations Screening for Abdominal Aortic Aneurysm The U.S. Preventive Services Task Force (Task Force) has issued a final recommendation statement on Screening for Abdominal Aortic Aneurysm. This final ...

  15. Exploring Urban Screens

    Directory of Open Access Journals (Sweden)

    Zlatan Krajina

    2009-12-01

    Full Text Available There is a tautological tendency in the widespread claims that urban space is 'me-diated'. Never before has the citizen, it is argued, been confronted with such an unprecedented array of signage. I depart from the rhetoric of 'biggest-ever-saturation' as not necessarily untrue, but as insufficient in exploring the diverse spatial operations of urban screens. I examine some contemporary cases of ani-mated architectural surfaces, informational panels, and advertising billboards, with reference to much longer standing cultural practices of spatial management in modern cities, such as illumination, to suggest that the contemporary display media do not mediate the city anew but re-invent urban space as a field of ubiqui-tous mediation. From that standpoint I suggest exploring urban screens as a both singular visual agents and indivisible items in plural structural assemblages, b complementary forces of public illumination, and c complex perceptual platforms in visual play of scale and distance.

  16. Colorectal cancer screening: the time to act is now.

    Science.gov (United States)

    Brenner, Hermann; Stock, Christian; Hoffmeister, Michael

    2015-10-13

    Colorectal cancer (CRC) is the third most common cancer and the fourth most common cause of cancer deaths globally. However, there is overwhelming evidence that a large proportion of CRC cases and deaths could be prevented by screening. Nevertheless, CRC screening programmes are offered in a minority of countries only and often suffer from low adherence. Factors potentially accounting for hesitant implementation of and low adherence to CRC screening may include a lower attention in the public and the media than for other cancers and the fairly long follow-up time needed to fully disclose screening effects on CRC incidence and mortality. The latter results from the very slow development of most CRCs through the adenoma-carcinoma sequence, and it challenges the predominant or even exclusive reliance on evidence from randomized controlled trials in policy decisions on screening offers. Additional key elements of future research should include (1) studies evaluating diagnostic performance of novel biomarkers for non-invasive or minimally invasive CRC screening in true screening settings, (2) modelling studies evaluating expected short- and long-term impact, effectiveness, and cost-effectiveness of various screening options, and (3) timely and close monitoring of process quality and outcomes of existing and planned CRC screening programmes. Most importantly, however, translation of the vast existing evidence on CRC screening into actual screening programmes with the best possible levels of adherence needs to be fostered. This can be best achieved in the context of organized programmes. Depending on available infrastructure and resources, epidemiological patterns, population preferences, and costs, different screening offers might be preferred. According to current evidence, colonoscopy, flexible sigmoidoscopy, and faecal occult blood tests (preferably faecal immunochemical tests) are prime candidates for effective and cost-effective screening options, and

  17. Screening Devices at School

    DEFF Research Database (Denmark)

    Ratner, Helene

    2011-01-01

    it as a “screening device”. It is a “device” in the sense that it distributes agency, and it “screens” in the word’s multiple meanings: “projecting” as in creating a viewer position;“sifting” and “systematizing” as in discriminating “knowledge” from mere “opinionings”; and “protecting” teachers from noise. Using...

  18. Validity of data in the Danish Colorectal Cancer Screening Database

    DEFF Research Database (Denmark)

    Thomsen, Mette Kielsholm; Njor, Sisse Helle; Linnemann, Dorte

    2017-01-01

    Background: In Denmark, a nationwide screening program for colorectal cancer was implemented in March 2014. Along with this, a clinical database for program monitoring and research purposes was established. Objective: The aim of this study was to estimate the agreement and validity of diagnosis...... and procedure codes in the Danish Colorectal Cancer Screening Database (DCCSD). Methods: All individuals with a positive immunochemical fecal occult blood test (iFOBT) result who were invited to screening in the first 3 months since program initiation were identified. From these, a sample of 150 individuals...... of codes varied from moderate to high. Thus, the DCCSD may be a valuable data source for future research on colorectal cancer screening....

  19. Push for the Second Screen

    DEFF Research Database (Denmark)

    Sørensen, Jannick Kirk; Sørensen, Lene Tolstrup

    Users’ perception of the relation between the TV screen and a secondary screen (e.g. smartphone or tablet) is examined empirically in a pilot project through a low-fi prototype and interviews. Early observations indicate that the user value/acceptance of push-messages delivered to the second screen...

  20. Screening for Carotid Artery Stenosis

    Science.gov (United States)

    ... including stroke, heart attack or death. In addition, screening all adults will lead to many false-positive results because ... Force reviewed. 1 The Task Force recommends against screening for asymptomatic carotid artery stenosis in the general adult population . Grade D Notes 1 screening Conducting an ...

  1. Push for the Second Screen

    DEFF Research Database (Denmark)

    Sørensen, Jannick Kirk; Sørensen, Lene Tolstrup

    Users’ perception of the relation between the TV screen and a secondary screen (e.g. smartphone or tablet) is examined empirically in a pilot project through a low-fi prototype and interviews. Early observations indicate that the user value/acceptance of push-messages delivered to the second screen...

  2. Cancer Information Summaries: Screening/Detection

    Science.gov (United States)

    ... Cancer Screening (PDQ®) patient | health professional Skin Cancer Screening (PDQ®) patient | health professional Stomach (Gastric) Cancer Screening (PDQ®) patient | health professional Testicular ...

  3. Monitoring Leverage

    DEFF Research Database (Denmark)

    Geanakoplos, John; Heje Pedersen, Lasse

    2014-01-01

    We argue that leverage is a central element of economic cycles and discuss how leverage can be properly monitored. While traditionally the interest rate has been regarded as the single key feature of a loan, we contend that the size of the loan, i.e., the leverage, is in fact a more important...... measure of systemic risk. Indeed, systemic crises tend to erupt when highly leveraged economic agents are forced to deleverage, sending the economy into recession. We emphasize the importance of measuring both the average leverage on old loans (which captures the economy's vulnerability) and the leverage...... offered on new loans (which captures current credit conditions) since the economy enters a crisis when leverage on new loans is low and leverage on old loans is high. While leverage plays an important role in several economic models, the data on leverage is model-free and simply needs to be collected...

  4. Treaty Monitoring

    DEFF Research Database (Denmark)

    Canty, M.; Lingenfelder, I.; Nielsen, Allan Aasbjerg;

    2009-01-01

    This volume provides the reader with an overview of the state-of-the-art Earth Observation (EO) related research that deals with national and international security. An interdisciplinary approach was adopted in this book in order to provide the reader with a broad understanding on the uses...... of remote sensing technologies. The book therefore comprises management aspects (issues and priorities of security research, crisis response), applied methodologies and process chains (treaty monitoring, estimation of population densities and characteristics, border permeability models, damage assessment......, as well as project managers and decision makers working in the field of security having an interest in technical solutions. The integrative use of many figures and sample images are ideal in enabling the non-technical reader to grasp quickly the modern technologies that are being researched in the area...

  5. Intracranial pressure monitoring

    Science.gov (United States)

    ICP monitoring; CSF pressure monitoring ... There are 3 ways to monitor pressure in the skull (intracranial pressure). INTRAVENTRICULAR CATHETER The intraventricular catheter is the most accurate monitoring method. To insert an intraventricular catheter, a ...

  6. The Effect of Using Dual Screen Computer Panel to the Neck-Shoulder Muscle Activity among Group of Students

    Directory of Open Access Journals (Sweden)

    Shamsul Bahri TAMRIN

    2016-03-01

    Full Text Available Background: Workstation design has shift from using single monitor screen to dual monitor screens, which may impose some impacts towards the muscles activity. This study aimed to determine the effect of using dual monitor screen computer to the neck-shoulder muscle activity among computer user.Method: This experimental study was conducted in 2015 among 28 healthy students in University Malaysia Perlis. The muscle activity of sternocleidomastoid and trapezius were recorded using surface electromyography (sEMG as the participants perform two types of computer task: (1 proofreading task for 10 minutes (2 typing task for 20 minutes in setting; single and dual monitor screens.Results: There was a significant reduction in the median frequency of the left trapezius muscle (t=-2.515, P=0.018. Sternocleidomastoid muscle activity for both sides also showed a significant reduction in the median frequency where right SCM (t=-2.579, P=0.016 and left SCM (t=-2.345, P=0.027. When compared between both setup of screen display, it is showed that dual screen gave a lower trend of muscle activity compared to single screen.Conclusions: Using dual screen may results in increasing the movement frequency and reducing the static strain in the neck-shoulder muscle area. Keywords: Dual monitor screen, Neck-shoulder muscles, Surface electromyography

  7. Screening for Infectious Diseases among Newly Arrived Migrants in EU/EEA Countries—Varying Practices but Consensus on the Utility of Screening

    Directory of Open Access Journals (Sweden)

    Tommi Kärki

    2014-10-01

    Full Text Available Screening is one possible tool for monitoring infectious diseases among migrants. However, there is limited information on screening programmes targeted for newly arrived migrants in EU/EEA countries. Our aim was to investigate the implementation, practices and usefulness of these programmes. We conducted a survey among country experts from EU/EEA countries and Switzerland, asking whether their countries had implemented screening programmes. We also estimated the association between the implementation of these programmes and the rate of asylum-seekers in the population. Of the countries, 16 (59% had implemented screening programmes and 15 (56% had national guidelines. The rate of asylum-seekers was associated with implementation of screening programmes (p = 0.014. Screening was performed most often for tuberculosis; most commonly on holding level, and was targeted to specific migrant groups in over half of the countries performing screening. Twenty-five of all the country experts (96% considered screening among migrants useful, and 24 (92% would welcome EU level guidelines for screening. The implementation of screening programmes varied, and the practices were different among countries. Our survey suggests, that establishing EU level guidelines for screening would be useful, although they would have to take into account differences between individual countries.

  8. Is GPS telemetry location error screening beneficial?

    Science.gov (United States)

    Ironside, Kirsten E.; Mattson, David J.; Arundel, Terry; Hansen, Jered R.

    2017-01-01

    The accuracy of global positioning system (GPS) locations obtained from study animals tagged with GPS monitoring devices has been a concern as to the degree it influences assessments of movement patterns, space use, and resource selection estimates. Many methods have been proposed for screening data to retain the most accurate positions for analysis, based on dilution of precision (DOP) measures, and whether the position is a two dimensional or three dimensional fix. Here we further explore the utility of these measures, by testing a Telonics GEN3 GPS collar's positional accuracy across a wide range of environmental conditions. We found the relationship between location error and fix dimension and DOP metrics extremely weak (r2adj ∼ 0.01) in our study area. Environmental factors such as topographic exposure, canopy cover, and vegetation height explained more of the variance (r2adj = 15.08%). Our field testing covered sites where sky-view was so limited it affected GPS performance to the degree fix attempts failed frequently (fix success rates ranged 0.00–100.00% over 67 sites). Screening data using PDOP did not effectively reduce the location error in the remaining dataset. Removing two dimensional fixes reduced the mean location error by 10.95 meters, but also resulted in a 54.50% data reduction. Therefore screening data under the range of conditions sampled here would reduce information on animal movement with minor improvements in accuracy and potentially introduce bias towards more open terrain and vegetation.

  9. Fluorescence Polarization Assays in Small Molecule Screening

    Science.gov (United States)

    Lea, Wendy A.; Simeonov, Anton

    2011-01-01

    Importance of the field Fluorescence polarization (FP) is a homogeneous method that allows rapid and quantitative analysis of diverse molecular interactions and enzyme activities. This technique has been widely utilized in clinical and biomedical settings, including the diagnosis of certain diseases and monitoring therapeutic drug levels in body fluids. Recent developments in the field has been symbolized by the facile adoption of FP in high-throughput screening (HTS) and small molecule drug discovery of an increasing range of target classes. Areas covered in this review The article provides a brief overview on the theoretical foundation of FP, followed by updates on recent advancements in its application for various drug target classes, including G-protein coupled receptors (GPCRs), enzymes and protein-protein interactions (PPIs). The strengths and weaknesses of this method, practical considerations in assay design, novel applications, and future directions are also discussed. What the reader will gain The reader will be informed of the most recent advancements and future directions of FP application to small molecule screening. Take home message In addition to its continued utilization in high-throughput screening, FP has expanded into new disease and target areas and has been marked by increased use of labeled small molecule ligands for receptor binding studies. PMID:22328899

  10. Final screening round of the NELSON lung cancer screening trial : the effect of a 2.5-year screening interval

    NARCIS (Netherlands)

    Yousaf-Khan, Uraujh; van der Aalst, Carlijn; de Jong, Pim A; Heuvelmans, Marjolein; Scholten, Ernst; Lammers, Jan-Willem; van Ooijen, Peter; Nackaerts, Kristiaan; Weenink, Carla; Groen, Harry; Vliegenthart, Rozemarijn; Ten Haaf, Kevin; Oudkerk, Matthijs; de Koning, Harry

    2016-01-01

    BACKGROUND: In the USA annual lung cancer screening is recommended. However, the optimal screening strategy (eg, screening interval, screening rounds) is unknown. This study provides results of the fourth screening round after a 2.5-year interval in the Dutch-Belgian Lung Cancer Screening trial (NEL

  11. Overdiagnosis in screening mammography in Denmark

    DEFF Research Database (Denmark)

    Njor, Sisse Helle; Olsen, Anne Helene; Blichert-Toft, Mogens

    2013-01-01

    To use data from two longstanding, population based screening programmes to study overdiagnosis in screening mammography.......To use data from two longstanding, population based screening programmes to study overdiagnosis in screening mammography....

  12. 75 FR 70557 - Endocrine Disruptor Screening Program; Draft Policies and Procedures for Screening Safe Drinking...

    Science.gov (United States)

    2010-11-17

    ... Protection Agency Endocrine Disruptor Screening Program; Draft Policies and Procedures for Screening Safe..., 2010 / Notices#0;#0; ] ENVIRONMENTAL PROTECTION AGENCY Endocrine Disruptor Screening Program; Draft... requiring Tier 1 screening under the Endocrine Disruptor Screening Program (EDSP) of substances for...

  13. Contamination monitoring

    Energy Technology Data Exchange (ETDEWEB)

    Alamares, A.L. [Philippine Nuclear Research Inst., Diliman, Quezon City (Philippines)

    1997-06-01

    By virture of Republic Act 2067, as amended the Philippine Atomic Energy Commission (PAEC), now renamed Philippine Nuclear Research Institute (PNRI) is the government agency charged with the regulations and control of radioactive materials in the Philippines. The protection against the hazards of non-ionizing radiation is being monitored by the Radiological Health Service (RHS) of the Department of Health pursuant to the provision of Presidental Decree 480. The RHS issues licenses for possession, handling, and use of x-ray machines and equipment, both industrial and medical, and provide radiation protection training to x-ray technologists and technicians. As part of its regulatory function, the PNRI is charged with the responsibility of assuring that the radiation workers and the public are protected from the hazards associated with the possession, handling, production, manufacturing, and the use of radioactive materials and atomic energy facilities in the Philippines. The protection of radiation workers from the hazards of ionizing radiation has always been a primary concern of PNRI and by limiting the exposure of radiation workers, the risk to population is kept to within acceptable level. In this paper, the following items are described: radiation protection program, radiation protection services, radiation control, and problems encountered/recommendation. (G.K.)

  14. Screening for renovascular hypertension.

    Science.gov (United States)

    Dunnick, N R; Sfakianakis, G N

    1991-05-01

    The most common curable cause of high blood pressure is renovascular hypertension. Although hypertension is common in the United States, only a minority, approximately 1%, of patients have a renovascular cause. Using clinical criteria, a subgroup of these patients can be selected in which the prevalence of renovascular hypertension will be approximately 15%. In these selected patients, it is appropriate to proceed to a radiographic screening modality to look for a significant renal artery stenosis. The choice of modality should reflect the strengths and expertise of each specific institution. Hypertensive urography is no longer recommended for screening. Excellent results have been reported with intravenous DSRA in institutions where a strong interest in this procedure exists. Furthermore, intravenous DSRA is easily coupled with the collection of renal vein samples for renin assay. Intravenous DSRA, however, has not maintained widespread use. Although the radionuclide renogram is no longer adequate as a radiographic screening tool, stimulation with an ACE inhibitor, such as captopril or enalaprilat, may produce excellent results. In many institutions, this is the most appropriate examination. Furthermore, it is relatively noninvasive. Merely detecting a significant renal artery stenosis does not, however, mean the patient has renovascular hypertension. Both hypertension and a renal artery stenosis may be present and not be causally related. Because renovascular hypertension is, at least initially, renin mediated, the demonstration of increased renin production by the ipsilateral kidney should confirm renovascular hypertension. Prospective application of these results to patients undergoing revascularization techniques, however, has been disappointing. This may be related to problems in patient preparation, sample collection, renin assay, or even the physiology of chronic hypertension, which is incompletely renin mediated. Thus, offering revascularization only to

  15. Abolishing mammography screening programs?

    OpenAIRE

    2015-01-01

    Biller-Andorno and Jüni (2014), in a widely debated commentary published in the May 22 issue of the New England Journal of Medicine, accept the concept that mammography every 2 years from age 50 can decrease breast cancer mortality by 20%, that is, from five to four deaths per 1000 women over a 10-year period. Both the absolute and the relative risk of breast cancer death may vary depending on the baseline mortality rates in various populations and on the impact of screening mammography in re...

  16. Audiometry screening and interpretation.

    Science.gov (United States)

    Walker, Jennifer Junnila; Cleveland, Leanne M; Davis, Jenny L; Seales, Jennifer S

    2013-01-01

    The prevalence of hearing loss varies with age, affecting at least 25 percent of patients older than 50 years and more than 50 percent of those older than 80 years. Adolescents and young adults represent groups in which the prevalence of hearing loss is increasing and may therefore benefit from screening. If offered, screening can be performed periodically by asking the patient or family if there are perceived hearing problems, or by using clinical office tests such as whispered voice, finger rub, or audiometry. Audiometry in the family medicine clinic setting is a relatively simple procedure that can be interpreted by a trained health care professional. Pure-tone testing presents tones across the speech spectrum (500 to 4,000 Hz) to determine if the patient's hearing levels fall within normal limits. A quiet testing environment, calibrated audiometric equipment, and appropriately trained personnel are required for in-office testing. Pure-tone audiometry may help physicians appropriately refer patients to an audiologist or otolaryngologist. Unilateral or asymmetrical hearing loss can be symptomatic of a central nervous system lesion and requires additional evaluation.

  17. Molecular screening in galactosemia

    Energy Technology Data Exchange (ETDEWEB)

    Elsas, L.J.; Singh, R.; Fernhoff, P.M. [Emory Univ., Atlanta, GA (United States)] [and others

    1994-09-01

    Classical galactosemia (G/G) is caused by the absence of galactose-1-phosphate uridyl transferase (GALT) activity while the Duarte allele produces partial impairment and a specific biochemical phenotype. Cloning and sequencing of the human GALT gene has enabled the identification of prevalent mutations for both Classical and Duarte alleles. The G allele is caused by a Q188R codon mutation in exon 6 in 70% of a Caucasian population while the D allele is caused by an N134D codon mutation in exon 10. Since the Q188R sequence creates a new Hpa II site and the N314D sequence creates a new Sin I site, it is relatively easy to screen for both mutations by multiplex PCR and restriction digest. Here we describe a method for detection of new mutations producing impaired GALT. Patient DNAs are subjected to SSCP (single strand conformational polymorphism) analysis of their 11 GALT exons. Direct sequencing of the exons targeted by SSCP has revealed many codon changes: IVSC 956 (a splice acceptor site loss), S135L, V151A, E203K, A320T, and Y323D. Two of these codon changes, V151A and S135L, have been confirmed as mutations by finding impaired GALT activity in a yeast expression system. We conclude that molecular screening of GALT DNA will clarify the structural biology of GALT and the pathophysiology of galactosemia.

  18. [Primary cervical cancer screening].

    Science.gov (United States)

    Vargas-Hernández, Víctor Manuel; Vargas-Aguilar, Víctor Manuel; Tovar-Rodríguez, José María

    2015-01-01

    Cervico-uterine cancer screening with cytology decrease incidence by more than 50%. The cause of this cancer is the human papilloma virus high risk, and requires a sensitive test to provide sufficient sensitivity and specificity for early detection and greater interval period when the results are negative. The test of the human papilloma virus high risk, is effective and safe because of its excellent sensitivity, negative predictive value and optimal reproducibility, especially when combined with liquid-based cytology or biomarkers with viral load, with higher sensitivity and specificity, by reducing false positives for the detection of cervical intraepithelial neoplasia grade 2 or greater injury, with excellent clinical benefits to cervical cancer screening and related infection of human papilloma virus diseases, is currently the best test for early detection infection of human papillomavirus and the risk of carcinogenesis. Copyright © 2015 Academia Mexicana de Cirugía A.C. Published by Masson Doyma México S.A. All rights reserved.

  19. Current Cervical Carcinoma Screening Guidelines

    Directory of Open Access Journals (Sweden)

    Megan J. Schlichte

    2015-05-01

    Full Text Available A formidable threat to the health of women, cervical carcinoma can be prevented in many cases with adequate screening. The current guidelines for cervical carcinoma screening were created as joint recommendations of the American Cancer Society (ACS, the American Society for Colposcopy and Cervical Pathology (ASCCP and the American Society for Clinical Pathology (ASCP in 2012, and later accepted and promoted by the American Congress of Obstetricians and Gynecologists (ACOG. The 2012 recommendations underscore the utility of molecular testing as an adjunct to cytology screening for certain women and provide guidance to clinicians based on different risk-benefit considerations for different ages. This manuscript will review screening techniques and current recommendations for cervical cancer screening and human papilloma virus (HPV testing, as well as possible future screening strategies.

  20. Principles of successful cancer screening.

    Science.gov (United States)

    Smith, R A

    1999-10-01

    Screening for cancer is the application of various tests to apparently healthy individuals in order to identify who among them has occult disease, which may be either invasive disease or a precursor lesion. For any given cancer site, the potential of screening to reduce morbidity and mortality is based on well-defined criteria for the evaluation of screening effectiveness and on acceptable performance to be realized in the average community setting. Screening programs are most successful when they are organized into a system that leads to high rates of participation, high quality, and constant surveillance and evaluation. If the elements that contribute to a successful screening program are not well organized and integrated, then the fullest potential of screening will not be realized.

  1. Designing Business Touch Screen Applications

    OpenAIRE

    Čeč, Neža

    2013-01-01

    This thesis covers conversion of a business application from a standard application to a touch screen version. The first part describes basic functional characteristics of touch screen applications, like their structure and user interaction. Later on we describe technological characteristics that cover different technologies and frameworks for developing touch screen applications. These theoretic chapters are followed by a practical example of converting a business application to a touch scre...

  2. The Hereford Screen: A Prehistory

    Directory of Open Access Journals (Sweden)

    The Hereford Screen: A Prehistory

    2017-04-01

    Full Text Available This paper explores two contexts for Francis Skidmore and George Gilbert Scott's screen at Hereford Cathedral. First, it locates the screen within a succession of choir screens at Hereford from the middle ages to the present, thereby charting the typology of the choir screen within a single institutional context. Second, it shows that Skidmore and Scott's work at Hereford should be understood in light of their related work at Lichfield and Salisbury, and that, more distantly, the three buildings were subject to significant "improvements" in the eighteenth century that Scott and Skidmore's work was intended to erase.

  3. Cancer Screening in Older Patients.

    Science.gov (United States)

    Salzman, Brooke; Beldowski, Kathryn; de la Paz, Amanda

    2016-04-15

    Although cancer is the second leading cause of death among persons 65 years and older, there is a paucity of clinical trial data about the effectiveness and harms of cancer screening in this population. Given the heterogeneous nature of the older population, cancer screening in these patients should not be based on age alone. Studies suggest that a life expectancy of at least 10 years is necessary to derive a survival benefit from screening for breast and colorectal cancers; therefore, screening for these cancers is not recommended in those with a life expectancy of less than 10 years. Prostate cancer screening, if performed at all, should not be performed after 69 years of age. Cervical cancer screening may be stopped after 65 years of age if the patient has an adequate history of negative screening results. An individualized approach to cancer screening decisions involves estimating life expectancy, determining the potential benefits and harms of screenings, and weighing those benefits and harms in relation to the patient's values and preferences.

  4. Comments on Gaugino Screening

    Energy Technology Data Exchange (ETDEWEB)

    Cohen, Timothy; Hook, Anson; Wecht, Brian

    2012-02-15

    Gauge mediated models of supersymmetry breaking often exhibit 'gaugino screening,' where to leading order in F, gaugino masses are unaffected by higher dimensional Kahler potential interactions between the supersymmetry breaking spurion and the messengers. We provide a derivation of this phenomenon which utilizes the gaugino counterterm originally proposed in the context of anomaly mediation by Dine and Seiberg. We argue that this counterterm is present when there are non-zero messenger F-terms, and can cancel the leading order Feynman diagram contribution to the gaugino mass. We provide a nontrivial check of the regulator independence of our results by performing the computation using both dimensional reduction and Pauli-Villars. This analysis reconciles an apparent contradiction between diagrammatics and analytic continuation into superspace.

  5. Congenital cataract screening

    Directory of Open Access Journals (Sweden)

    Zhale Rajavi

    2016-01-01

    Full Text Available Congenital cataract is a leading cause of visual deprivation which can damage the developing visual system of a child; therefore early diagnosis, management and long-term follow-up are essential. It is recommended that all neonates be screened by red reflex examination at birth and suspected cases be referred to ophthalmic centers. Early surgery (1 year is highly recommended. After surgery, amblyopia treatment and periodic follow-up examinations should be started as soon as possible to achieve a satisfactory visual outcome. Practitioners should consider the possibility of posterior capsular opacity, elevated intraocular pressure and amblyopia during follow-up, especially in eyes with microphthalmia and/or associated congenital anomalies. All strabismic children should undergo slit lamp examination prior to strabismus surgery to rule out congenital lens opacities. From a social point of view, equal and fair medical care should be provided to all children regardless of gender.

  6. Electromagnetic pollution. Screens accused

    Energy Technology Data Exchange (ETDEWEB)

    Vincent, J.

    1996-04-01

    A recent experiment carried out by M. Bastide (Montpellier University, France) has shown an important increase of mortality, immunosuppression and morphological changes for chicks embryos when submitted to the very low frequency electromagnetic field of a personal computer screen during incubation. Similar effects on pregnant women working in front of cathode ray tubes have never been demonstrated. The paper gives an overview of the epidemiological studies carried out so far to determine the possible noxious effects of electromagnetic fields on public health. In particular, EdF (Electricite de France) has started three different inquiries involving 400000 workmens from electric power industry in order to determine some possible correlation between the exposure to electromagnetic fields and the occurrence of leukemias, brain tumors and melanomas. William Dab, from EdF Medical Studies Service indicates that only a very small relation with the occurrence of brain tumors and acute myeloid leukemias have been shown so far. (J.S.). 4 refs., 2 photos.

  7. Congenital Cataract Screening

    Science.gov (United States)

    Rajavi, Zhale; Sabbaghi, Hamideh

    2016-01-01

    Congenital cataract is a leading cause of visual deprivation which can damage the developing visual system of a child; therefore early diagnosis, management and long-term follow-up are essential. It is recommended that all neonates be screened by red reflex examination at birth and suspected cases be referred to ophthalmic centers. Early surgery (1 year) is highly recommended. After surgery, amblyopia treatment and periodic follow-up examinations should be started as soon as possible to achieve a satisfactory visual outcome. Practitioners should consider the possibility of posterior capsular opacity, elevated intraocular pressure and amblyopia during follow-up, especially in eyes with microphthalmia and/or associated congenital anomalies. All strabismic children should undergo slit lamp examination prior to strabismus surgery to rule out congenital lens opacities. From a social point of view, equal and fair medical care should be provided to all children regardless of gender. PMID:27621790

  8. Perspectives on behavioral and social science research on cancer screening.

    Science.gov (United States)

    Rakowski, William; Breslau, Erica S

    2004-09-01

    The first section in the current article offered several themes that characterize behavioral and social science cancer screening research to date and are likely to be relevant for studying the adoption and utilization of future screening technologies. The themes discussed included the link between epidemiologic surveillance and the priorities of intervention, the "at-risk" perspective that often guides research on screening and initiatives to redress disparities, the need to monitor the diversification of personal screening histories, the range of intervention groups and study designs that can be tested, the importance of including key questions in population-level surveys and national health objectives, and the desirability of clarifying the characteristics of cancer screening that make it an attractive field of study in its own right. The second section commented on emerging areas in which more research will allow additional lessons to be learned. The other articles in the current supplement presented many more lessons in a variety of areas, and other authors are encouraged to write similar articles that help to identify general themes characterizing cancer screening research.

  9. Holter and Event Monitors

    Science.gov (United States)

    ... Share this page from the NHLBI on Twitter. Holter and Event Monitors Also known as ambulatory EKG; continuous EKG; EKG event monitors. Holter and event monitors are small, portable electrocardiogram devices ...

  10. Monitoring Knowledge Base (MKB)

    Data.gov (United States)

    U.S. Environmental Protection Agency — The Monitoring Knowledge Base (MKB) is a compilation of emissions measurement and monitoring techniques associated with air pollution control devices, industrial...

  11. Depression screening optimization in an academic rural setting.

    Science.gov (United States)

    Aleem, Sohaib; Torrey, William C; Duncan, Mathew S; Hort, Shoshana J; Mecchella, John N

    2015-01-01

    Primary care plays a critical role in screening and management of depression. The purpose of this paper is to focus on leveraging the electronic health record (EHR) as well as work flow redesign to improve the efficiency and reliability of the process of depression screening in two adult primary care clinics of a rural academic institution in USA. The authors utilized various process improvement tools from lean six sigma methodology including project charter, swim lane process maps, critical to quality tree, process control charts, fishbone diagrams, frequency impact matrix, mistake proofing and monitoring plan in Define-Measure-Analyze-Improve-Control format. Interventions included change in depression screening tool, optimization of data entry in EHR. EHR data entry optimization; follow up of positive screen, staff training and EHR redesign. Depression screening rate for office-based primary care visits improved from 17.0 percent at baseline to 75.9 percent in the post-intervention control phase (p<0.001). Follow up of positive depression screen with Patient History Questionnaire-9 data collection remained above 90 percent. Duplication of depression screening increased from 0.6 percent initially to 11.7 percent and then decreased to 4.7 percent after optimization of data entry by patients and flow staff. Impact of interventions on clinical outcomes could not be evaluated. Successful implementation, sustainability and revision of a process improvement initiative to facilitate screening, follow up and management of depression in primary care requires accounting for voice of the process (performance metrics), system limitations and voice of the customer (staff and patients) to overcome various system, customer and human resource constraints.

  12. Overdiagnosis in breast cancer screening

    DEFF Research Database (Denmark)

    Lynge, Elsebeth; Beau, Anna-Belle; Christiansen, Peer

    2017-01-01

    Overdiagnosis in breast cancer screening is an important issue. A recent study from Denmark concluded that one in three breast cancers diagnosed in screening areas in women aged 50-69 years were overdiagnosed. The purpose of this short communication was to disentangle the study's methodology...

  13. Costs of Colorectal Cancer Screening

    Centers for Disease Control (CDC) Podcasts

    2017-04-04

    A health economist talks about studies on figuring out the costs of running a colorectal cancer screening program, and how this can lead to better screening.  Created: 4/4/2017 by National Center for Chronic Disease Prevention and Health Promotion (NCCDPHP).   Date Released: 4/4/2017.

  14. Screening College Students for Hypercholesterolemia.

    Science.gov (United States)

    Faigel, Harris C.

    1992-01-01

    Describes one college's mandatory mass cholesterol screening for new students. Each year, over 30 beginning students with unknown hypercholesterolemia were detected. The program suggests that mass screening efficiently and economically identifies students who would benefit from cholesterol reduction, a modifiable risk in coronary artery disease.…

  15. Non-participation in screening

    DEFF Research Database (Denmark)

    Dugué, Pierre-Antoine; Lynge, Elsebeth; Bjerregaard, Beth;

    2012-01-01

    To determine the impact of comprehensiveness of cytology registration on the proportion of cervical cancer patients without a recent screening history.......To determine the impact of comprehensiveness of cytology registration on the proportion of cervical cancer patients without a recent screening history....

  16. Risks of Colorectal Cancer Screening

    Science.gov (United States)

    ... screening tests have different risks or harms. Screening tests may cause anxiety when you are thinking about or getting ready ... is cancer when there really isn't) can cause anxiety and is usually followed by more tests (such as biopsy ), which also have risks. The ...

  17. Singularities in Speckled Speckle: Screening

    CERN Document Server

    Kessler, David A

    2008-01-01

    We study screening of optical singularities in random optical fields with two widely different length scales. We call the speckle patterns generated by such fields speckled speckle, because the major speckle spots in the pattern are themselves highly speckled. We study combinations of fields whose components exhibit short- and long-range correlations, and find unusual forms of screening.

  18. Mammographic screening: keeping women alive

    NARCIS (Netherlands)

    Verbeek, A.L.M.

    2011-01-01

    Evaluation of: Tabar L, Vitak B, Chen TH et al. Swedish Two-County Trial: impact of mammographic screening on breast cancer mortality during 3 decades. Radiology 260(3), 658-663 (2011). In the 1980s, the periodic invitation of women aged 40-69 years for mammographic screening in the Swedish Two-Coun

  19. NELSON lung cancer screening study

    NARCIS (Netherlands)

    Y. Zhao (Yingru); X. Xie (Xueqian); H.J. de Koning (Harry); W.P. Mali (Willem); R. Vliegenthart (Rozemarijn); M. Oudkerk (Matthijs)

    2011-01-01

    textabstractThe Dutch-Belgian Randomized Lung Cancer Screening Trial (Dutch acronym: NELSON study) was designed to investigate whether screening for lung cancer by low-dose multidetector computed tomography (CT) in high-risk subjects will lead to a decrease in 10-year lung cancer mortality of at

  20. Cervical cancer screening at crossroads

    DEFF Research Database (Denmark)

    Lynge, Elsebeth; Rygaard, Carsten; Baillet, Miguel Vazquez-Prada

    2014-01-01

    Cervical screening has been one of the most successful public health prevention programmes. For 50 years, cytology formed the basis for screening, and detected cervical intraepithelial lesions (CIN) were treated surgically to prevent progression to cancer. In a high-risk country as Denmark......, screening decreased the incidence of cervical cancer from 34 to 11 per 100,000, age-standardized rate (World Standard Population). Screening is, however, also expensive; Denmark (population: 5.6 million) undertakes close to half a million tests per year, and has 6-8 CIN-treated women for each prevented...... cancer case. The discovery of human papillomavirus (HPV) as the cause of cervical cancer dramatically changed perspectives for disease control. Screening with HPV testing was launched around 1990, and preventive HPV vaccination was licensed in 2006. Long-term randomized controlled trials (RCT...

  1. Optimal screening for genetic diseases.

    Science.gov (United States)

    Nævdal, Eric

    2014-12-01

    Screening for genetic diseases is performed in many regions and/or ethnic groups where there is a high prevalence of possibly malign genes. The propagation of such genes can be considered a dynamic externality. Given that many of these diseases are untreatable and give rise to truly tragic outcomes, they are a source of societal concern, and the screening process should perhaps be regulated. This paper incorporates a standard model of genetic propagation into an economic model of dynamic management to derive cost benefit rules for optimal screening. The highly non-linear nature of genetic dynamics gives rise to perhaps surprising results that include discontinuous controls and threshold effects. One insight is that any screening program that is in place for any amount of time should screen all individuals in a target population. The incorporation of genetic models may prove to be useful to several emerging fields in economics such as genoeconomics, neuroeconomics and paleoeconomics.

  2. ASSAY FOR RAPID SCREENING OF PHYTOCHEMICALS AS ANTIMICROBIAL AGENTS

    OpenAIRE

    Ghosh Saurav; Indranil Mukherjee; Ashoke Ranjan Thakur; Shaon Ray Chaudhuri

    2013-01-01

    The present study aims to develop a rapid method for antibiotic sensitivity detection and screening of natural products for antimicrobial activity. The dimension of WBC in blood film was found to get altered when seeded with bacteria and monitored under light microscope. The shrinkage was prevented in response to antibiotic treatment and validated using statistical analysis (two sample one tailed Z test). Thus here is a prompt (4 h) assay system for detection of blood infection, antibiotic se...

  3. New Eye-Tracking Techniques May Revolutionize Mental Health Screening

    Science.gov (United States)

    2015-11-04

    persons or animals in the scene. Repeating the analysis for individual saccades as they developed over the time spent scanning an image revealed, for both...Neuron PreviewsNew Eye-Tracking Techniques May Revolutionize Mental Health ScreeningLaurent Itti1,* 1Computer Science Department, Psychology...phar- macy. Today, many pharmacies in the United States of America provide free blood pressure monitors that you can use as a rapid health indicator

  4. Screening of Newborn Saturation

    Directory of Open Access Journals (Sweden)

    Senem Ozgur

    2014-08-01

    Full Text Available In terms of the incidence, congenital heart diseases ranks first among congenital problems in the neonatal period. Although some of those diseases are with significant clinical findings, they might be insignificant in most cases. Standardization methods have been studied in variety of points, and oxygen saturation by pulse oximetry is thougt to be a good alternative to physical examination. In several studies, it is mentioned that some of congenital heart diseases are diagnosed by saturation screening. However, the benefits of this method are marred with the false negative and false positive rates. Therefore, in 2011 American Academy of Pediatrics has revised its saturation algorithm for scanning. It was aimed to have a standardization in saturation detecting time and evaluation of achieved saturation in newborns. Despite all efforts, some newborns with congenital heart disease are not diagnosed before discharging. We beleive that the details of saturation measurements are needed to be carefully evaluated because although these measurements are widely used their details are not well known. [Archives Medical Review Journal 2014; 23(4.000: 587-604

  5. The evolution of screening.

    Science.gov (United States)

    Gray, J A

    2001-01-01

    Botany is usually considered to be the gentlest of sciences with botanists being regarded as people who study relatively safe specimens, compared with, for example, anthropologists or microbiologists. However, botanists have their moments, particularly when collecting new species. The great botanists of the eighteenth and nineteenth centuries risked their lives in collecting and bringing back species, which we now take for granted, and Robert Brown was one of these adventurers, a young Scot who accompanied Sir Joseph Banks to New Holland. It was not, however, for his adventurous lifestyle that Brown is remembered but for his startling observation of the movements of pollen grains on a microscope slide. He noted that the pollen grains were in perpetual agitated motion, without purpose or direction but full of energy. This motion, called Brownian motion, arises from the movement of molecules, and Brownian motion is the term that has been applied to much of healthcare, including many screening programmes, which have in the past been marked more by the amount of energy and activity than by a clear sense of direction or positive achievement.

  6. The screening Horndeski cosmologies

    Science.gov (United States)

    Starobinsky, Alexei A.; Sushkov, Sergey V.; Volkov, Mikhail S.

    2016-06-01

    We present a systematic analysis of homogeneous and isotropic cosmologies in a particular Horndeski model with Galileon shift symmetry, containing also a Λ-term and a matter. The model, sometimes called Fab Five, admits a rich spectrum of solutions. Some of them describe the standard late time cosmological dynamic dominated by the Λ-term and matter, while at the early times the universe expands with a constant Hubble rate determined by the value of the scalar kinetic coupling. For other solutions the Λ-term and matter are screened at all times but there are nevertheless the early and late accelerating phases. The model also admits bounces, as well as peculiar solutions describing ``the emergence of time''. Most of these solutions contain ghosts in the scalar and tensor sectors. However, a careful analysis reveals three different branches of ghost-free solutions, all showing a late time acceleration phase. We analyse the dynamical stability of these solutions and find that all of them are stable in the future, since all their perturbations stay bounded at late times. However, they all turn out to be unstable in the past, as their perturbations grow violently when one approaches the initial spacetime singularity. We therefore conclude that the model has no viable solutions describing the whole of the cosmological history, although it may describe the current acceleration phase. We also check that the flat space solution is ghost-free in the model, but it may acquire ghost in more general versions of the Horndeski theory.

  7. The screening Horndeski cosmologies

    CERN Document Server

    Starobinsky, Alexei A; Volkov, Mikhail S

    2016-01-01

    We present a systematic analysis of homogeneous and isotropic cosmologies in a particular Horndeski model with Galileon shift symmetry, containing also a $\\Lambda$-term and a matter. The model, sometimes called Fab Five, admits a rich spectrum of solutions. Some of them describe the standard late time cosmological dynamic dominated by the $\\Lambda$-term and matter, while at the early times the universe expands with a constant Hubble rate determined by the value of the scalar kinetic coupling. For other solutions the $\\Lambda$-term and matter are screened at all times but there are nevertheless the early and late accelerating phases. The model also admits bounces, as well as peculiar solutions describing "the emergence of time". Most of these solutions contain ghosts in the scalar and tensor sectors. However, a careful analysis reveals three different branches of ghost-free solutions, all showing a late time acceleration phase. We analyze the dynamical stability of these solutions and find that all of them are...

  8. Touch/Screen

    Directory of Open Access Journals (Sweden)

    Daniel Ross

    2015-12-01

    Full Text Available In 2004 Bernard Stiegler posed “the tragic question of cinema” as that of the germ of regres-­‐‑ sion to television and pornography it has always contained, just as in 1944 Adorno and Hork-­‐‑ heimer argued that Enlightenment reason has always contained a germ of regression making possible a prostitution of theory leading only to the threat of fascism. If comparable threats attend Stiegler’s cinematic question, then this implies the need for an account of this potential for regression, that is, an account of the relationship between desire, technology and knowledge. Tracing the aporias of the origin of desire and trauma in psychoanalysis is one crucial way to pursue this account. Exiting these aporias depends on recognizing that the origin of desire has for human beings always been technical, and hence that the instruments of desire form its conditions and condition its forms. By thus analysing the staging of desire and the setting of fantasy it becomes possible to reflect, for example, on what it means that for Genet fascism was theatre, that for Syberberg Hitler was cinema, and that for Stiegler the new prostitution of the tele-­‐‑visual graphic is digital and algorithmic. Hence arises the potentially tragic question of the possibility or otherwise, in the age of the ubiquitous screen, of a new cinematic invention and a new cinematic practice.

  9. Dysphonia risk screening protocol

    Directory of Open Access Journals (Sweden)

    Katia Nemr

    2016-03-01

    Full Text Available OBJECTIVE: To propose and test the applicability of a dysphonia risk screening protocol with score calculation in individuals with and without dysphonia. METHOD: This descriptive cross-sectional study included 365 individuals (41 children, 142 adult women, 91 adult men and 91 seniors divided into a dysphonic group and a non-dysphonic group. The protocol consisted of 18 questions and a score was calculated using a 10-cm visual analog scale. The measured value on the visual analog scale was added to the overall score, along with other partial scores. Speech samples allowed for analysis/assessment of the overall degree of vocal deviation and initial definition of the respective groups and after six months, the separation of the groups was confirmed using an acoustic analysis. RESULTS: The mean total scores were different between the groups in all samples. Values ranged between 37.0 and 57.85 in the dysphonic group and between 12.95 and 19.28 in the non-dysphonic group, with overall means of 46.09 and 15.55, respectively. High sensitivity and specificity were demonstrated when discriminating between the groups with the following cut-off points: 22.50 (children, 29.25 (adult women, 22.75 (adult men, and 27.10 (seniors. CONCLUSION: The protocol demonstrated high sensitivity and specificity in differentiating groups of individuals with and without dysphonia in different sample groups and is thus an effective instrument for use in voice clinics.

  10. Data Quality Screening Service

    Science.gov (United States)

    Strub, Richard; Lynnes, Christopher; Hearty, Thomas; Won, Young-In; Fox, Peter; Zednik, Stephan

    2013-01-01

    A report describes the Data Quality Screening Service (DQSS), which is designed to help automate the filtering of remote sensing data on behalf of science users. Whereas this process often involves much research through quality documents followed by laborious coding, the DQSS is a Web Service that provides data users with data pre-filtered to their particular criteria, while at the same time guiding the user with filtering recommendations of the cognizant data experts. The DQSS design is based on a formal semantic Web ontology that describes data fields and the quality fields for applying quality control within a data product. The accompanying code base handles several remote sensing datasets and quality control schemes for data products stored in Hierarchical Data Format (HDF), a common format for NASA remote sensing data. Together, the ontology and code support a variety of quality control schemes through the implementation of the Boolean expression with simple, reusable conditional expressions as operands. Additional datasets are added to the DQSS simply by registering instances in the ontology if they follow a quality scheme that is already modeled in the ontology. New quality schemes are added by extending the ontology and adding code for each new scheme.

  11. Functional Screening of Core Promoter Activity.

    Science.gov (United States)

    Even, Dan Y; Kedmi, Adi; Ideses, Diana; Juven-Gershon, Tamar

    2017-01-01

    The core promoter is the DNA sequence that recruits the basal transcription machinery and directs accurate initiation of transcription. It is an active contributor to gene expression that can be rationally designed to manipulate the levels of expression. Core promoter function can be analyzed using different experimental approaches. Here, we describe the qualitative and quantitative analysis of engineered core promoter functions using the EGFP reporter gene that is driven by distinct core promoters. Expression plasmids are transfected into different mammalian cell lines, and the resulting fluorescence is monitored by live cell imaging , as well as by flow cytometry. In order to verify that the transcriptional activity of the examined core promoters is indeed a function of their activity, as opposed to differences in DNA uptake, real-time quantitative PCR analysis is performed. Importantly, the described methodology for functional screening of core promoter activity has enabled the analysis of engineered potent core promoters for extended time periods.

  12. Status of implementation and organization of cancer screening in the European Union Member States - summary results from the second European screening report.

    Science.gov (United States)

    Basu, Partha; Ponti, Antonio; Anttila, Ahti; Ronco, Guglielmo; Senore, Carlo; Vale, Diama Bhadra; Segnan, Nereo; Tomatis, Mariano; Soerjomataram, Isabelle; Primic Žakelj, Maja; Dillner, Joakim; Elfström, Klara Miriam; Lönnberg, Stefan; Sankaranaryanan, Rengaswamy

    2017-09-23

    The second report on the implementation status of cancer screening in European Union (EU) was published in 2017. The report described the implementation status, protocols and organization (updated till 2016) and invitation coverage (for index year 2013) of breast, cervical and colorectal cancer screening in the EU. Experts in screening programme monitoring (N=80) from the EU Member States having access to requisite information in their respective countries provided data on breast, cervical and colorectal cancer screening through online questionnaires. Data was collected for screening performed in the framework of publicly mandated programmes only. Filled in questionnaires were received from 26 Member States for all three sites and from one Member State for breast cancer only. Substantial improvement in screening implementation using population-based approach was documented. Among the age-eligible women, 94.7% were residents of Member States implementing or planning population-based breast cancer screening in 2016, compared to 91.6% in 2007. The corresponding figures for cervical cancer screening were 72.3% and 51.3% in 2016 and 2007 respectively. Most significant improvement was documented for colorectal cancer screening with roll-out ongoing or completed in 17 Member States in 2016, compared to only five in 2007. So the access to population-based screening increased to 72.4% of the age-eligible populations in 2016 as opposed to only 42.6% in 2007. The invitation coverage was highly variable, ranging from 0.2%-111% for breast cancer, 7.6%-105% for cervical cancer and 1.8%-127% for colorectal cancer in the target populations. In spite of the considerable progress, much work remains to be done to achieve optimal effectiveness. Continued monitoring, regular feedbacks and periodic reporting are needed to ensure the desired impacts of the programmes. This article is protected by copyright. All rights reserved. © 2017 UICC.

  13. Monitor resultaten geluid 2000

    NARCIS (Netherlands)

    Jabben J; Potma CJM; Swart WJR; LLO

    2001-01-01

    As part of an enhanced effort in monitoring the environmental quality in 1999, the RIVM set up a noise monitoring programme. This programme forms part of the project, "Development of a monitoring system for noise and disturbance", which aims at establishing a number of permanent sites for monitoring

  14. FIELD SCREENING FOR HALOGENATED VOLATILE ORGANIC COMPOUNDS

    Energy Technology Data Exchange (ETDEWEB)

    John F. Schabron; Joseph F. Rovani Jr.; Theresa M. Bomstad

    2002-06-01

    Western Research Institute (WRI) initiated exploratory work towards the development of new field screening methodology and a test kit to measure halogenated volatile organic compounds (VOCs) in the field. Heated diode and corona discharge sensors are commonly used to detect leaks of refrigerants from air conditioners, freezers, and refrigerators. They are both selective to the presence of carbon-halogen bonds. Commercially available heated diode and corona discharge leak detectors were procured and evaluated for halogenated VOC response. The units were modified to provide a digital readout of signal related to VOC concentration. Sensor response was evaluated with carbon tetrachloride and tetrachloroethylene (perchloroethylene, PCE), which represent halogenated VOCs with and without double bonds. The response characteristics were determined for the VOCs directly in headspace in Tedlar bag containers. Quantitation limits in air were estimated. Potential interferences from volatile hydrocarbons, such as toluene and heptane, were evaluated. The effect of humidity was studied also. The performance of the new devices was evaluated in the laboratory by spiking soil samples and monitoring headspace for halogenated VOCs. A draft concept of the steps for a new analytical method was outlined. The results of the first year effort show that both devices show potential utility for future analytical method development work towards the goal of developing a portable test kit for screening halogenated VOCs in the field.

  15. Sepsis Patient Detection and Monitor Based on Auto-BN.

    Science.gov (United States)

    Jiang, Yu; Sha, Lui; Rahmaniheris, Maryam; Wan, Binhua; Hosseini, Mohammad; Tan, Pengliu; Berlin, Richard B

    2016-04-01

    Sepsis is a life-threatening condition caused by an inappropriate immune response to infection, and is a leading cause of elderly death globally. Early recognition of patients and timely antibiotic therapy based on guidelines improve survival rate. Unfortunately, for those patients, it is often detected late because it is too expensive and impractical to perform frequent monitoring for all the elderly. In this paper, we present a risk driven sepsis screening and monitoring framework to shorten the time of onset detection without frequent monitoring of all the elderly. Within this framework, the sepsis ultimate risk of onset probability and mortality is calculated based on a novel temporal probabilistic model named Auto-BN, which consists of time dependent state, state dependent property, and state dependent inference structures. Then, different stages of a patient are encoded into different states, monitoring frequency is encoded into the state dependent property, and screening content is encoded into different state dependent inference structures. In this way, the screening and monitoring frequency and content can be automatically adjusted when encoding the sepsis ultimate risk into the guard of state transition. This allows for flexible manipulation of the tradeoff between screening accuracy and frequency. We evaluate its effectiveness through empirical study, and incorporate it into existing medical guidance system to improve medical healthcare.

  16. To screen or nor to screen: the prostate cancer dilemma

    Directory of Open Access Journals (Sweden)

    Nelson N Stone

    2015-02-01

    Full Text Available The European Randomized Study of Screening for Prostate (ERSPC has updated their previous seminal report on prostate cancer mortality comparing screened men to controls. Now with 13 years follow-up, the rate ratio of prostate cancer mortality was 0.79 favoring the screened population. The authors concluded that there was a "substantial reduction in prostate cancer mortality attributable to testing with prostate-specific antigen (PSA" but they also stated that a "quantification of harms" needed to be addressed. The issue of harms was not addressed by the ERSPC (at least not in this report and hence this additional statement most likely reflects the controversy currently surrounding the risks associated with over-diagnosis and treatment of indolent diseases inadvertently detected by a screening protocol. [1] In addition, the positive results from this trial conflict with those of the prostate, lung, colorectal and ovarian (PLCO [2] study and require further elaboration.

  17. Dielectric screening in semiconductors

    Science.gov (United States)

    Harrison, Walter A.; Klepeis, John E.

    1988-01-01

    Intra-atomic and interatomic Coulomb interactions are incorporated into bond-orbital theory, based upon universal tight-binding parameters, in order to treat the effects of charge redistribution in semiconductor bonds. The dielectric function ɛ(q) is obtained for wave numbers in a [100] direction. The screening of differences in average hybrid energy across a heterojunction is calculated in detail, indicating that the decay length for the potential depends upon the relative values of Madelung and intra-atomic Coulomb terms. The parameters used here predict an imaginary decay length and thus an oscillating potential near the interface. The same theory is applied to point defects by imbedding a cluster in a matrix lattice, taking charges in that lattice to be consistent with continuum theory. Illustrating the theory with a phosphorus impurity in silicon, it is seen that the impurity and its neighboring atoms have charges on the order of only one-tenth of an electronic charge, alternating in sign from neighbor to neighbor as for planar defects. Although there are shifts in the term values on the order of a volt, the difference in these shifts for neighboring atoms is much smaller so that the effect on the bonds is quite small. This behavior is analogous to the response of a dielectric continuum to a point charge: The medium is locally neutral except at the center of the cluster and there are slowly varying potentials e2/ɛr. Because of this slow variation, free-atom term values should ordinarily suffice for the calculation of bond properties and bond lengths at impurities. Corrections are larger for homovalent substitutions such as carbon in silicon.

  18. The screening Horndeski cosmologies

    Energy Technology Data Exchange (ETDEWEB)

    Starobinsky, Alexei A. [L.D. Landau Institute for Theoretical Physics RAS,Moscow 119334 (Russian Federation); Department of General Relativity and Gravitation, Institute of Physics,Kazan Federal University,Kremlevskaya street 18, 420008 Kazan (Russian Federation); Sushkov, Sergey V. [Department of General Relativity and Gravitation, Institute of Physics,Kazan Federal University,Kremlevskaya street 18, 420008 Kazan (Russian Federation); Volkov, Mikhail S. [Laboratoire de Mathématiques et Physique Théorique CNRS-UMR 7350,Université de Tours,Parc de Grandmont, 37200 Tours (France); Department of General Relativity and Gravitation, Institute of Physics,Kazan Federal University,Kremlevskaya street 18, 420008 Kazan (Russian Federation)

    2016-06-06

    We present a systematic analysis of homogeneous and isotropic cosmologies in a particular Horndeski model with Galileon shift symmetry, containing also a Λ-term and a matter. The model, sometimes called Fab Five, admits a rich spectrum of solutions. Some of them describe the standard late time cosmological dynamic dominated by the Λ-term and matter, while at the early times the universe expands with a constant Hubble rate determined by the value of the scalar kinetic coupling. For other solutions the Λ-term and matter are screened at all times but there are nevertheless the early and late accelerating phases. The model also admits bounces, as well as peculiar solutions describing “the emergence of time”. Most of these solutions contain ghosts in the scalar and tensor sectors. However, a careful analysis reveals three different branches of ghost-free solutions, all showing a late time acceleration phase. We analyse the dynamical stability of these solutions and find that all of them are stable in the future, since all their perturbations stay bounded at late times. However, they all turn out to be unstable in the past, as their perturbations grow violently when one approaches the initial spacetime singularity. We therefore conclude that the model has no viable solutions describing the whole of the cosmological history, although it may describe the current acceleration phase. We also check that the flat space solution is ghost-free in the model, but it may acquire ghost in more general versions of the Horndeski theory.

  19. Risk Profiling May Improve Lung Cancer Screening

    Science.gov (United States)

    A new modeling study suggests that individualized, risk-based selection of ever-smokers for lung cancer screening may prevent more lung cancer deaths and improve the effectiveness and efficiency of screening compared with current screening recommendations

  20. Abnormal Cervical Cancer Screening Test Results

    Science.gov (United States)

    ... FREQUENTLY ASKED QUESTIONS FAQ187 GYNECOLOGIC PROBLEMS Abnormal Cervical Cancer Screening Test Results • What is cervical cancer screening? • What causes abnormal cervical cancer screening test results? • ...

  1. Evaluation of diabetic foot screening in Primary Care.

    Science.gov (United States)

    Alonso-Fernández, Margarita; Mediavilla-Bravo, José Javier; López-Simarro, Flora; Comas-Samper, José Manuel; Carramiñana-Barrera, Francisco; Mancera-Romero, José; de Santiago Nocito, Ana

    2014-01-01

    To ascertain whether patients with type 2 diabetes are screened for diabetic foot, and to analyze the factors related to patients and centers associated to performance of such screening. A multicenter, epidemiological, cross-sectional study was conducted. The clinical records of 443 patients with type 2 diabetes monitored at Primary Care for at least 12 months were reviewed. Demographic and healthcare variables and characteristics of the primary care center were recorded. In the previous year, 51.2% of patients had been trained on foot self-care, 56.4% had undergone foot inspection, 39.5% had been examined with a monofilament, and palpation of peripheral pulses and measurement of the ankle-brachial index were performed in 45.8 and 10.1% of patients, respectively. Diabetic foot screening (inspection, monofilament testing, and palpation of peripheral pulses) was performed in 37% of study patients. Ulcer risk stratification was done in 12.4% of patients. A significant association was found between diabetic foot screening and presence of foot deformities (Pdiabetic foot screening and ulcer risk stratification in patients with type 2 diabetes in Primary Care was poor. Copyright © 2013 SEEN. Published by Elsevier Espana. All rights reserved.

  2. Osteoporosis Screening Preferences of Older Adults

    OpenAIRE

    Nayak, Smita; Roberts, Mark S.; Greenspan, Susan L

    2009-01-01

    We aimed to examine older adults' osteoporosis screening test preferences, willingness to travel for screening, and willingness to pay for screening. A survey was mailed to 1830 women and men ≥ 60 years old in Pennsylvania, assessing screening test preference (among dual-energy x-ray absorptiometry (DXA), heel quantitative ultrasound (QUS), and risk assessment tools), willingness to travel 20 miles for a better screening test, and willingness to pay $100 for a better screening test, as well a...

  3. Inventions on GUI for Touch Sensitive Screens

    OpenAIRE

    Mishra, Umakant

    2014-01-01

    A touch sensitive screen displays the information on the screen and also receives the input by sensing a user's touch on the same screen. This mechanism facilitates system interaction directly through the screen without needing a mouse or keyboard. This method has the advantage to make the system compact by removing keyboard, mouse and similar interactive device. However there are certain difficulties to implement a touch screen interface. The display screens of portable devices are becoming ...

  4. Breast cancer screening in Italy: evaluating key performance indicators for time trends and activity volumes.

    Science.gov (United States)

    Giordano, Livia; Castagno, Roberta; Giorgi, Daniela; Piccinelli, Cristiano; Ventura, Leonardo; Segnan, Nereo; Zappa, Marco

    2015-01-01

    Together with the National centre for screening monitoring (ONS), GISMa supports annual collection of data on national breast screening activities. Aggregated data on implementation and performance are gathered through a standardized form to calculate process and impact indicators. Analyzed data belong to 153 local programmes in the period 2006-2011 (2006-2012 for participation rate only). During the whole period, Italian crude participation rate exceeded GISMa's acceptable standard (50%), even though a higher participation in northern and central Italy compared to southern Italy and Islands was observed. Time trend analysis of diagnostic indicators confirmed in 2011 an adequate quality of breast screening performance, especially at subsequent screening. Recall rate at initial screening did not reach the acceptable standard (performance was achieved at subsequent screening. The same trend was followed by the overall detection rate and positive predictive value. They both showed a progressive reduction (from 6.2‰ in 2006 to 4.5‰ in 2011 for DR and from 8.0% in 2006 to 5.2% in 2011 for PPV, respectively) at initial screening and a good, stable trend at subsequent screening. Activity volume analysis shows that in programmes with greater activity (test/year ≥10,000) RR at both initial and subsequent screening has a better performance. This is also true for DR and PPV where programmes with high volumes of activity do better, especially when compared with those that interpret fewer than 5,000 mammograms per year. In spite of a few limits, these results are reassuring, and they reward the efforts made by screening professionals. It is therefore important to continue to monitor screening indicators and suggest, test, and evaluate new strategies for continuous improvement.

  5. First Trimester Down Syndrome Screen

    Science.gov (United States)

    ... disorder such as Down syndrome (trisomy 21) or Edwards syndrome (trisomy 18) . The first trimester screen is one ... chromosome material that results in Down syndrome or Edwards syndrome , the levels of PAPP-A tend to be ...

  6. Screening Newborns' Hearing Now Standard

    Science.gov (United States)

    ... this page please turn Javascript on. Feature: Taste, Smell, Hearing, Language, Voice, Balance Screening Newborns' Hearing Now ... emailing NIDCDinfo@nidcd.nih.gov . Read More "Taste, Smell, Hearing, Language, Voice, Balance" Articles At Last: A ...

  7. Screening Effect in Charge Qubit

    Institute of Scientific and Technical Information of China (English)

    HUA Ming; XIAO Xiao; GAO Yi-Bo

    2011-01-01

    We study the influence of screening effect on quantum decoherence for charge qubit and the process of quantum information storage. When the flux produced by the circulating current in SQUID loop is considered, screening effect is formally characterized by a LC resonator. Using large-detuning condition and Fr(o)hlich transformation in the qubit-cavity-resonator system, we calculate the decoherence factor for charge qubit and the effective qubit-cavity Hamiltonian. The decoherence factor owns a factorized structure, it shows that screening effect is a resource of decoherence for charge qubit. The effective Hamiltonian shows that the screening effect results in a frequency shift for charge qubit and a modified qubit-cavity coupling constant induced by a LC resonator.

  8. Risks of Cervical Cancer Screening

    Science.gov (United States)

    ... are at increased risk for HPV infections. Other risk factors for cervical cancer include: Giving birth to many children. Smoking cigarettes. Using oral contraceptives ("the Pill"). Having a weakened immune system . Cervical Cancer Screening ...

  9. RAS - Screens & Assays - Drug Discovery

    Science.gov (United States)

    The RAS Drug Discovery group aims to develop assays that will reveal aspects of RAS biology upon which cancer cells depend. Successful assay formats are made available for high-throughput screening programs to yield potentially effective drug compounds.

  10. Proposal of Screening Method of Sleep Disordered Breathing Using Fiber Grating Vision Sensor

    Science.gov (United States)

    Aoki, Hirooki; Nakamura, Hidetoshi; Nakajima, Masato

    Every conventional respiration monitoring technique requires at least one sensor to be attached to the body of the subject during measurement, thereby imposing a sense of restraint that results in aversion against measurements that would last over consecutive days. To solve this problem, we developed a respiration monitoring system for sleepers, and it uses a fiber-grating vision sensor, which is a type of active image sensor to achieve non-contact respiration monitoring. In this paper, we verified the effectiveness of the system, and proposed screening method of the sleep disordered breathing. It was shown that our system could equivalently measure the respiration with thermistor and accelerograph. And, the respiratory condition of sleepers can be grasped by our screening method in one look, and it seems to be useful for the support of the screening of sleep disordered breathing.

  11. Breast Cancer Screening and Prevention.

    Science.gov (United States)

    Nattinger, Ann B; Mitchell, Julie L

    2016-06-07

    This issue provides a clinical overview of breast cancer screening and prevention, focusing on risk assessment, screening, prevention, and practice improvement. The content of In the Clinic is drawn from the clinical information and education resources of the American College of Physicians (ACP), including MKSAP (Medical Knowledge and Self-Assessment Program). Annals of Internal Medicine editors develop In the Clinic in collaboration with the ACP's Medical Education and Publishing divisions and with the assistance of additional science writers and physician writers.

  12. Vision Screening by Color Photography

    Science.gov (United States)

    Jayroe, R.; Richardson, J. R.; Kerr, J.; Hay, S.; Mcbride, R.

    1985-01-01

    Screening test developed for detecting a range of vision defects in eye, including common precursors to amblyopia. Test noninvasive, safe, and administered easily in field by operator with no medical training. Only minimal momentary cooperation of subject required: Thus, test shows promise for use with very young children. Test produces color-slide images of retinas of eyes under specially-controlled lighting conditions. Trained observer screens five children per minute.

  13. The Use of Multiple Monitor and KVM (Keyboard, Video, and Mouse) Technologies in an Educational Setting

    Science.gov (United States)

    Snyder, Robin

    2004-01-01

    Having more than one screen of usable space can enhance productivity, both inside and outside of the classroom. So can using one keyboard, screen, and mouse with multiple computers. This paper (and session) will cover the author's use of multiple monitor and KVM (keyboard, video, and mouse) technologies both inside and outside the classroom, with…

  14. Phenotypic screens targeting neurodegenerative diseases.

    Science.gov (United States)

    Zhang, Minhua; Luo, Guangrui; Zhou, Yanjiao; Wang, Shaohui; Zhong, Zhong

    2014-01-01

    Neurodegenerative diseases affect millions of people worldwide, and the incidences increase as the population ages. Disease-modifying therapy that prevents or slows disease progression is still lacking, making neurodegenerative diseases an area of high unmet medical need. Target-based drug discovery for disease-modifying agents has been ongoing for many years, without much success due to incomplete understanding of the molecular mechanisms underlying neurodegeneration. Phenotypic screening, starting with a disease-relevant phenotype to screen for compounds that change the outcome of biological pathways rather than activities at certain specific targets, offers an alternative approach to find small molecules or targets that modulate the key characteristics of neurodegeneration. Phenotypic screens that focus on amelioration of disease-specific toxins, protection of neurons from degeneration, or promotion of neuroregeneration could be potential fertile grounds for discovering therapeutic agents for neurodegenerative diseases. In this review, we will summarize the progress of compound screening using these phenotypic-based strategies for this area, with a highlight on unique considerations for disease models, assays, and screening methodologies. We will further provide our perspectives on how best to use phenotypic screening to develop drug leads for neurodegenerative diseases.

  15. Indirect discrimination and breast screening.

    Science.gov (United States)

    Botha, J L; Manku-Scott, T K; Moledina, F; Williams, A

    1993-01-01

    Uptake of screening services in inner-city communities has been low, particularly in older age groups, lower social classes, and ethnic minorities. In Leicester City, where up to 25% of the population belong to ethnic minorities, this may have important implications for breast screening. We randomly sampled 701 inner-city women aged 45 to 64 years, stratified by neighborhood and by women's "likely home language." Trained interviewers succeeded in interviewing 79% of those eligible, and we report here a preliminary analysis of 413 respondents. Knowledge of breast cancer and screening varied markedly and significantly by actual language: 60.4% of English-speaking and 12.5% of non-English-speaking women correctly answered 10 or more questions (of 14) about breast cancer and screening (chi 2(1) = 89.884; P = .000). Despite that, 80% or more women stated their intention to attend for screening and assessment if necessary, irrespective of neighborhood, language, age, or social class. We suggest that the difference in knowledge between language groups arose from indirect discrimination in the way in which health-related information is disseminated in British society. However, after providing appropriate screening information, we report similarly high intended acceptance rates in the two language groups.

  16. Hepatocellular carcinoma: cost-effectiveness of screening. A systematic review

    Directory of Open Access Journals (Sweden)

    Ruggeri M

    2012-06-01

    Full Text Available Matteo RuggeriFacoltà di Economia, Università Cattolica del Sacro Cuore – sede di Roma, Rome, ItalyAbstract: Hepatocellular carcinoma (HCC is one of the most common tumors worldwide. HCC is a potential target for cancer surveillance (or screening as it occurs in well-defined, at-risk populations. Curative therapy is possible only for small tumors and screening strategy has been recommended by the US, Italian, and other international liver societies and is practiced widely, but its benefits are not clearly established. The objective of this study was to review the available evidence with respect to the cost-effectiveness of key technologies in the prevention HCC. The literature search was conducted with the support of PubMed. Firstly we selected articles by reading the abstracts. Secondly, we read the articles and the revision was further restricted, with the following as inclusion criteria: (1 full economic evaluation of HCC screening programs; (2 comparison between HCC techniques; (3 outcome measures expressed in terms of quality adjusted life years (QALY; (4 full text availability. The initial review of the literature yielded 346 articles. Of those, 288 were excluded at the first stage. Of those excluded, 108 did not meet the target, 106 did not present the cost analysis, 33 did not analyze the treatment of the disease, and in 41 the abstract was not available. Of the 58 included in the first step, seven examined the cost-effectiveness of different HCC screening techniques, seven investigated the cost-effectiveness of HCC screening versus no screening, and one looked at the cost-effectiveness of timing for HCC surveillance and monitoring, while 43 were about HBV vaccination and screening. We included only the seven articles examining the cost-effectiveness of different HCC screening techniques. In general, incidence is the key parameter which determines the cost-effectiveness of HCC screening. Discrepancies in the results exist when

  17. Autism Spectrum Disorder Screening Instruments for Very Young Children: A Systematic Review

    Directory of Open Access Journals (Sweden)

    Patricia O. Towle

    2016-01-01

    Full Text Available Research on ASD in infancy has provided a rationale for developing screening instruments for children from the first year of life to age of 18 months. A comprehensive literature search identified candidate screening tools. Using methodological probe questions adapted from the Quality Assessment of Diagnostic Accuracy Studies (QUADAS, two Level 1 and three Level 2 screening instruments were reviewed in detail. Research evidence conclusions were that instrument development was in beginning phases, is not yet strong, and requires further development. Clinical recommendations were to continue vigilant developmental and autism surveillance from the first year on but to use the screening instruments per se only for high-risk children rather than for population screening, with considerations regarding feasibility for individual settings, informing caregivers about strengths and weaknesses of the tool, and monitoring new research.

  18. CLAD DEGRADATION - FEPS SCREENING ARGUMENTS

    Energy Technology Data Exchange (ETDEWEB)

    R. Schreiner

    2004-10-21

    The purpose of this report is to evaluate and document the screening of the clad degradation features, events, and processes (FEPs) with respect to modeling used to support the Total System Performance Assessment-License Application (TSPA-LA). This report also addresses the effect of certain FEPs on both the cladding and the commercial spent nuclear fuel (CSNF), DOE-owned spent nuclear fuel (DSNF), and defense high-level waste (DHLW) waste forms, as appropriate to address the effects on multiple materials and both components (FEPs 2.1.09.09.0A, 2.1.09.11.0A, 2.1.11.05.0A, 2.1.12.02.0A, and 2.1.12.03.0A). These FEPs are expected to affect the repository performance during the postclosure regulatory period of 10,000 years after permanent closure. Table 1-1 provides the list of cladding FEPs, including their screening decisions (include or exclude). The primary purpose of this report is to identify and document the analysis, screening decision, and TSPA-LA disposition (for included FEPs) or screening argument (for excluded FEPs) for these FEPs related to clad degradation. In some cases, where a FEP covers multiple technical areas and is shared with other FEP reports, this report may provide only a partial technical basis for the screening of the FEP. The full technical basis for shared FEPs is addressed collectively by the sharing FEP reports. The screening decisions and associated TSPA-LA dispositions or screening arguments from all of the FEP reports are cataloged in a project-specific FEPs database.

  19. Routine screening for postpartum depression.

    Science.gov (United States)

    Georgiopoulos, A M; Bryan, T L; Wollan, P; Yawn, B P

    2001-02-01

    Postpartum depression (PPD) is a common and often overlooked condition. Validated screening tools for PPD exist but are not commonly used. We present the 1-year outcome of a project to implement universal PPD screening at the 6-week postpartum visit. Universal screening with the Edinburgh Postnatal Depression Scale (EPDS) was implemented in all community postnatal care sites. One-year outcome assessments (diagnosis and treatment of PPD) were completed for a sample of the women screened using medical record review of all care they received during the first year postpartum. Sixty-eight (20%) of the 342 women whose medical records were reviewed had been given a documented diagnosis of postpartum depression, resulting in an estimated population rate of 10.7%. Depression was diagnosed in 35% of the women with elevated EPDS scores (> or =10) compared with 5% of the women with low EPDS scores (<10) in the first year postpartum. Treatment was provided for all women diagnosed with depression, including drug therapy for 49% and counseling for 78%. Four women were hospitalized for depression. Some degree of suicidal ideation was noted on the EPDS by 48 women but acknowledged in the chart of only 10 women, including 1 with an immediate hospitalization. The rate of diagnosis of postpartum depression in this community increased from 3.7% before the routine use of EPDS screening to 10.7% following screening. A high EPDS score was predictive of a diagnosis of postpartum depression, and the implementation of routine EPDS screening at 6 weeks postpartum was associated with an increase in the rate of diagnosed postpartum depression in this community.

  20. Blazar Monitoring List

    Data.gov (United States)

    National Aeronautics and Space Administration — This is a compilation of sources in major blazar monitoring programs. This list contains all blazars known to be regularly monitored, plus all the MOJAVE- &...

  1. Lunar Health Monitor Project

    Data.gov (United States)

    National Aeronautics and Space Administration — During the Phase II Lunar Health Monitor program, Orbital Research will develop a second generation wearable sensor suite for astronaut physiologic monitoring. The...

  2. Inductive Monitoring System (IMS)

    Data.gov (United States)

    National Aeronautics and Space Administration — IMS: Inductive Monitoring System The Inductive Monitoring System (IMS) is a tool that uses a data mining technique called clustering to extract models of normal...

  3. Flight Systems Monitor Project

    Data.gov (United States)

    National Aeronautics and Space Administration — This SBIR Phase I project will develop the Flight System Monitor which will use non-intrusive electrical monitoring (NEMO). The electronic system health of...

  4. Spacecraft Power Monitor Project

    Data.gov (United States)

    National Aeronautics and Space Administration — This SBIR Phase I project will develop the Spacecraft Power Monitor (SPM) which will use non-intrusive electrical monitoring (NEMO). NEMO transforms the power...

  5. Biological Monitoring Team

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — The Biological Monitoring Team (BMT) was a pilot project focused on addressing NWRS inventory and monitoring needs in Regions 3 and 5. The BMT was a precursor to the...

  6. Apnea monitor (image)

    Science.gov (United States)

    An apnea monitor checks the heart rate and respiration of the baby to make sure he or she is ... When either one falls below normal levels, the apnea monitor beeps to notify the care provider that ...

  7. Beam-profile monitor using a sodium-vapour

    CERN Multimedia

    1972-01-01

    Beam-profile monitor using a sodium-vapour curtain at 45 degrees to the ISR beam in Ring I (sodium generator is in white cylinder just left of centre). Electrons produced by ionization of the sodium vapour give an image of the beam on a fluorescent screen that is observed by a TV camera (at upper right).

  8. Calprotectin - A novel noninvasive marker for intestinal allograft monitoring

    NARCIS (Netherlands)

    Sudan, Debra; Vargas, Luciano; Sun, Yimin; Bok, Lisette; Dijkstra, Gerard; Langnas, Alan

    2007-01-01

    Objective: To identify a noninvasive screening test for intestinal allograft monitoring. Summary Background Data: Intestinal allograft rejection is difficult to distinguish from other causes of diarrhea and can rapidly lead to severe exfoliation or death. Protocol biopsies are standard for allograft

  9. [Effect of work with computer monitors on the visual system].

    Science.gov (United States)

    Niesłuchowska, M

    1994-03-01

    Computer users complain of numerous visual discomforts. The paper discusses those connected with eye fatigue and changes in visual functions associated with the work with monitor screens; these can be alleviated with an ergonomic organization of the work unit. There is a need for a determination of the requirements in visual functions for computer users.

  10. Risks of Stomach (Gastric) Cancer Screening

    Science.gov (United States)

    ... Gastric Cancer Treatment Stomach Cancer Prevention Stomach Cancer Screening Research Stomach (Gastric) Cancer Screening (PDQ®)–Patient Version What is ... from the . There is no standard or routine screening test for stomach cancer. Several types of screening tests have been ...

  11. Screening on urogenital Chlamydia trachomatis

    Directory of Open Access Journals (Sweden)

    Busse, Reinhard

    2005-12-01

    Full Text Available Introduction: Around 92 million urogenital infections are caused yearly by Chlamydia trachomatis worldwide [1]. The overall incidence of sexually transmitted diseases is increasing, as shown by the increases in the number of reported cases of syphilis and gonorrhea [2]. Chlamydia trachomatis infections are associated with various serious diseases in women, men and newborns, which could be, at least partially, avoided by means of early diagnosis and therapy. The Federal Joint Committee - responsible for decision-making concerning the benefit package of the German Social Health Insurance - has publicly announced the starting of deliberations on the issue of screening for Chlamydia trachomatis. Research Questions: The leading question to be answered is whether screening for Chlamydia trachomatis should be included in the German benefit basket. The aim of this report is to provide a summary of the available evidence concerning the issue of screening for Chlamydia trachomatis. Methods: The summary of published scientific evidence, including HTA reports, systematic reviews, guidelines and primary research is represented. The synthesis follows the structure given by the criteria of Wilson and Jungner [3] for the introduction of screening in a population: relevance of the condition, availability of an adequate test, effectiveness of screening, acceptance of the programme, and economical issues. A literature search was conducted for each aspect of the synthesis and the evidence has been summarised in evidence tables. Results: We identified five HTA reports from three European agencies [4], [5], [6], [7] and one from the USA [8]. In addition, we identified four guidelines from Northamerica [9], [10], [11], [12] and one from Europe [13]. A total of 56 primary research publications were included: relevance of the disease (n=26, availability of test (n=1, effectiveness of screening (n=11, acceptance of the programme (n=11, economical issues (n=7. Discussion

  12. Environmental monitoring lecture notes

    Energy Technology Data Exchange (ETDEWEB)

    Soldat, J.K.

    1965-03-01

    Criteria for environmental monitoring programs for radioactivity are presented. Standards for public exposure and the basis for maximum permissible concentration values are discussed. The value of pre-operational surveys, operation surveys, and emergency surveys in environmental monitoring programs is considered. The environmental monitoring program at the Hanford Area is described. 90 references.

  13. Inside the Monitor Model

    DEFF Research Database (Denmark)

    Carl, Michael; Dragsted, Barbara

    2012-01-01

    a “monitor model” according to which translators start with a literal default rendering procedure and where a monitor interrupts the default procedure when a problem occurs. This paper suggests an extension of the monitor model in which comprehension and production are processed in parallel by the default...

  14. Eletrodos fabricados por "silk-screen" Screen-printed electrodes

    Directory of Open Access Journals (Sweden)

    Valberes B. Nascimento

    1998-10-01

    Full Text Available A review dealing with the use of screen-printing technology to manufacture disposable electrodes is presented, covering in details virtually all the publications in the area up to early 1997 and including 206 references. The elements and different strategies on constructing modified electrodes are highlighted. Commercial and Home-made ink recipes are discussed. Microelectrode arrays, built by the combination of photostructuring and screen-printing technologies to the mass production of advanced disposable sensors, are also discussed. Future research trends are predicted.

  15. Newborn screening in Zhejiang, China

    Institute of Scientific and Technical Information of China (English)

    Riziwanguli Maitusong; Rukeya Japaer; ZHAO Zheng-yan; YANG Ru-lai; HUANG Xiao-lei; MAO Hua-qing

    2012-01-01

    Background It has been 11 years since newborn screening started in Zhejiang in 1999.The aim of this study was to analyze and summarize the status of newborn screening in Zhejiang from 1999 to 2009.Methods Blood samples were collected from the heels of newborns 72 hours after birth.We have conducted laboratory tests that the congenital hypothyroidism (CH) and circulating levels of thyroid-stimulating hormone (TSH) was detected.Blood phenylalanine (Phe) was detected for phenylketonuria (PKU).Dissociation-enhanced lanthanide fluorescent immunoassay (DELFIA) was used for detection.Results From 1999 to 2009,3875228 newborns were screened and 2309 cases were confirmed as CH and 155 cases were confirmed as PKU.The incidence of CH and PKU were 1:1678 and 1:25 001 respectively.Conclusion In 11 years,the Zhejiang newborn screening center screened more than 3.8 million newboms,and helped more than 2000 CH and PKU patients to obtain early treatment in order to prevent physical disability and mental retardation.

  16. BPA genetic monitoring - BPA Genetic Monitoring Project

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Initiated in 1989, this study monitors genetic changes associated with hatchery propagation in multiple Snake River sub-basins for Chinook salmon and steelhead. We...

  17. Screening for sexually transmitted infection pathogens in semen samples.

    Science.gov (United States)

    Peeling, Rw; Embree, J

    2005-03-01

    The transmission of sexually transmitted infection (STI) pathogens from an infected donor to the recipient of a semen donation in assisted conception may result not only in acute infection but also in long-term reproductive complications or adverse outcomes of pregnancy, including infection of the offspring. Screening for bacterial STI pathogens, Chlamydia trachomatis and Neisseria gonorrhoeae is strongly recommended because these pathogens can cause serious reproductive complications in the recipients of semen donations and infection in their offspring. Screening for these pathogens should be performed using the most sensitive methods, such as nucleic acid amplified tests. False-negative results due to inhibitory substances in the semen sample should be monitored using amplification controls. Where specimen transport is not a problem and culture facilities are available, N gonorrhoeae can also be detected by culture. Laboratories performing screening should subscribe to proficiency programs and have strict quality controls. Although Trichomonas vaginalis, group B streptococcus and genital mycoplasmas have been associated with adverse outcomes of pregnancy, the frequent finding of these organisms in healthy individuals brings into question the validity of mandatory inclusion of these organisms in the screening panel. Although viral STI pathogens and Treponema pallidum - the causative agent of syphilis - may be detected in semen, their presence may be more sensitively detected through antibody testing of the donor. Screening donors for HIV, hepatitis B and syphilis by serology is uniformly recommended in all of the guidelines, but the value of screening either donors or semen samples for cytomegalovirus, herpes simplex viruses and human papilloma viruses is less clear.

  18. Screening for Sexually Transmitted Infection Pathogens in Semen Samples

    Directory of Open Access Journals (Sweden)

    RW Peeling

    2005-01-01

    Full Text Available The transmission of sexually transmitted infection (STI pathogens from an infected donor to the recipient of a semen donation in assisted conception may result not only in acute infection but also in long-term reproductive complications or adverse outcomes of pregnancy, including infection of the offspring. Screening for bacterial STI pathogens, Chlamydia trachomatis and Neisseria gonorrhoeae is strongly recommended because these pathogens can cause serious reproductive complications in the recipients of semen donations and infection in their offspring. Screening for these pathogens should be performed using the most sensitive methods, such as nucleic acid amplified tests. False-negative results due to inhibitory substances in the semen sample should be monitored using amplification controls. Where specimen transport is not a problem and culture facilities are available, N gonorrhoeae can also be detected by culture. Laboratories performing screening should subscribe to proficiency programs and have strict quality controls. Although Trichomonas vaginalis, group B streptococcus and genital mycoplasmas have been associated with adverse outcomes of pregnancy, the frequent finding of these organisms in healthy individuals brings into question the validity of mandatory inclusion of these organisms in the screening panel. Although viral STI pathogens and Treponema pallidum -- the causative agent of syphilis -- may be detected in semen, their presence may be more sensitively detected through antibody testing of the donor. Screening donors for HIV, hepatitis B and syphilis by serology is uniformly recommended in all of the guidelines, but the value of screening either donors or semen samples for cytomegalovirus, herpes simplex viruses and human papilloma viruses is less clear.

  19. Particle Collection Efficiency for Nylon Mesh Screens

    OpenAIRE

    Cena, Lorenzo G.; Ku, Bon-Ki; Peters, Thomas M.

    2011-01-01

    Mesh screens composed of nylon fibers leave minimal residual ash and produce no significant spectral interference when ashed for spectrometric examination. These characteristics make nylon mesh screens attractive as a collection substrate for nanoparticles. A theoretical single-fiber efficiency expression developed for wire-mesh screens was evaluated for estimating the collection efficiency of submicrometer particles for nylon mesh screens. Pressure drop across the screens, the effect of part...

  20. Hadronic Screening in Improved Taste

    CERN Document Server

    Gupta, Sourendu

    2013-01-01

    We present our results on meson and nucleon screening masses in finite temperature two flavour QCD using smeared staggered valence quarks and staggered thin-link sea quarks with different lattice spacings and quark masses. We investigate optimization of smearing by observing its effects on the infrared (IR) and ultraviolet (UV) components of gluon and quark fields. The application of smearing to screening at finite temperature also provides a transparent window into the mechanism of the interplay of smearing and chiral symmetry. The improved hadronic operators show that above the finite temperature cross over, T_c, screening masses are consistent with weak-coupling predictions. There is also evidence for a rapid opening up of a spectral gap of the Dirac operator immediately above T_c.

  1. Unique interactive projection display screen

    Energy Technology Data Exchange (ETDEWEB)

    Veligdan, J.T.

    1997-11-01

    Projection systems continue to be the best method to produce large (1 meter and larger) displays. However, in order to produce a large display, considerable volume is typically required. The Polyplanar Optic Display (POD) is a novel type of projection display screen, which for the first time, makes it possible to produce a large projection system that is self-contained and only inches thick. In addition, this display screen is matte black in appearance allowing it to be used in high ambient light conditions. This screen is also interactive and can be remotely controlled via an infrared optical pointer resulting in mouse-like control of the display. Furthermore, this display need not be flat since it can be made curved to wrap around a viewer as well as being flexible.

  2. Microelectroporation device for genomic screening

    Energy Technology Data Exchange (ETDEWEB)

    Perroud, Thomas D.; Renzi, Ronald F.; Negrete, Oscar; Claudnic, Mark R.

    2014-09-09

    We have developed an microelectroporation device that combines microarrays of oligonucleotides, microfluidic channels, and electroporation for cell transfection and high-throughput screening applications (e.g. RNA interference screens). Microarrays allow the deposition of thousands of different oligonucleotides in microscopic spots. Microfluidic channels and microwells enable efficient loading of cells into the device and prevent cross-contamination between different oligonucleotides spots. Electroporation allows optimal transfection of nucleic acids into cells (especially hard-to-transfect cells such as primary cells) by minimizing cell death while maximizing transfection efficiency. This invention has the advantage of a higher throughput and lower cost, while preventing cross-contamination compared to conventional screening technologies. Moreover, this device does not require bulky robotic liquid handling equipment and is inherently safer given that it is a closed system.

  3. Enthalpy screen of drug candidates.

    Science.gov (United States)

    Schön, Arne; Freire, Ernesto

    2016-11-15

    The enthalpic and entropic contributions to the binding affinity of drug candidates have been acknowledged to be important determinants of the quality of a drug molecule. These quantities, usually summarized in the thermodynamic signature, provide a rapid assessment of the forces that drive the binding of a ligand. Having access to the thermodynamic signature in the early stages of the drug discovery process will provide critical information towards the selection of the best drug candidates for development. In this paper, the Enthalpy Screen technique is presented. The enthalpy screen allows fast and accurate determination of the binding enthalpy for hundreds of ligands. As such, it appears to be ideally suited to aid in the ranking of the hundreds of hits that are usually identified after standard high throughput screening.

  4. Nuclear reactor effluent monitoring

    Energy Technology Data Exchange (ETDEWEB)

    Minns, J.L.; Essig, T.H. [Nuclear Regulatory Commission, Washington, DC (United States)

    1993-12-31

    Radiological environmental monitoring and effluent monitoring at nuclear power plants is important both for normal operations, as well as in the event of an accident. During normal operations, environmental monitoring verifies the effectiveness of in-plant measures for controlling the release of radioactive materials in the plant. Following an accident, it would be an additional mechanism for estimating doses to members of the general public. This paper identifies the U.S. Nuclear Regulatory Commission (NRC) regulatory basis for requiring radiological environmental and effluent monitoring, licensee conditions for effluent and environmental monitoring, NRC independent oversight activities, and NRC`s program results.

  5. Arvelig hemokromatose - nytten av screening

    Directory of Open Access Journals (Sweden)

    Arne Åsberg

    2009-10-01

    Full Text Available Arvelig hemokromatose fører til jernopphopning i kroppen, men gir sjelden alvorlig helseskade. Nesten alle hemokromatosepasienter i vårt land er homozygote for C282Y-mutasjonen i HFE-genet. Omtrent 7 per 1000 innbyggere har denne genotypen. Alvorlig syke blir bare omkring 5-15% av homozygote menn og nesten ingen kvinner. Likevel er det holdepunkter for at screening for hemokromatose blant friske, yngre menn kan være kostnadseffektivt. Det er relativt lett å påvise om en person er disponert for sykdommen, i god tid før den bryter ut, og forebyggende behandling er billig og effektiv. Imidlertid kan vi ikke forutsi hvilke screeningpositive personer som ubehandlet får alvorlig sykdom. Et kontrollert forsøk med screening bør gjennomføresHereditary hemochromatosis – benefits of screening. Hereditary hemochromatosis leads to iron accumulation in the body; however, serious illness due to hemochromatosis is rare. In Norway, almost all patients with hemochromatosis are homozygous for the C282Ymutation in the HFE-gene, a genotype carried by about 7 per 1000 inhabitants. Serious complications are seen in only about 5-15% of homozygous men and in very few women. Nevertheless, screening young men for hemochromatosis may be cost-effective. Detecting predisposed men is relatively straightforward, and prophylactic treatment is cheap and effective. However, we can not predict, among screen-positive men, the few who untreated will become seriously ill. A controlled screening trial should be conducted.

  6. Computed tomographic characteristics of interval and post screen carcinomas in lung cancer screening

    NARCIS (Netherlands)

    Scholten, E.T.; Horeweg, N.; Koning, H.J. de; Vliegenthart, R.; Oudkerk, M.; Mali, W.P.; Jong, P.A. de

    2015-01-01

    OBJECTIVES: To analyse computed tomography (CT) findings of interval and post-screen carcinomas in lung cancer screening. METHODS: Consecutive interval and post-screen carcinomas from the Dutch-Belgium lung cancer screening trial were included. The prior screening and the diagnostic chest CT were

  7. Computed tomographic characteristics of interval and post screen carcinomas in lung cancer screening

    NARCIS (Netherlands)

    Scholten, Ernst Th.; Horeweg, Nanda; de Koning, Harry J.; Vliegenthart, Rozemarijn; Oudkerk, Matthijs; Mali, Willem P. Th. M.; de Jong, Pim A.

    Objectives To analyse computed tomography (CT) findings of interval and post-screen carcinomas in lung cancer screening. Methods Consecutive interval and post-screen carcinomas from the Dutch-Belgium lung cancer screening trial were included. The prior screening and the diagnostic chest CT were

  8. Computed tomographic characteristics of interval and post screen carcinomas in lung cancer screening

    NARCIS (Netherlands)

    Scholten, E.T.; Horeweg, N.; Koning, H.J. de; Vliegenthart, R.; Oudkerk, M.; Mali, W.P.; Jong, P.A. de

    2015-01-01

    OBJECTIVES: To analyse computed tomography (CT) findings of interval and post-screen carcinomas in lung cancer screening. METHODS: Consecutive interval and post-screen carcinomas from the Dutch-Belgium lung cancer screening trial were included. The prior screening and the diagnostic chest CT were re

  9. Environmental Monitoring Plan

    Energy Technology Data Exchange (ETDEWEB)

    Holland, R.C. [Science Applications International Corp., San Diego, CA (United States)

    1993-07-01

    This Environmental Monitoring Plan was written to fulfill the requirements of Department of Energy (DOE) Order 5400.1 and DOE Environmental Regulatory Guide DOE/EH 0173T. This Plan documents the background, organizational structure, and methods used for effluent monitoring and environmental surveillance at Sandia National Laboratories/California. The design, rationale, and historical results of the environmental monitoring system are discussed in detail. Throughout the Plan, recommendations for improvements to the monitoring system are made. This revision to the Environmental Monitoring Plan was written to document the changes made to the Monitoring Program during 1992. Some of the data (most notably the statistical analyses of past monitoring data) has not been changed.

  10. Screening_mgmt: a Python module for managing screening data.

    Science.gov (United States)

    Helfenstein, Andreas; Tammela, Päivi

    2015-02-01

    High-throughput screening is an established technique in drug discovery and, as such, has also found its way into academia. High-throughput screening generates a considerable amount of data, which is why specific software is used for its analysis and management. The commercially available software packages are often beyond the financial limits of small-scale academic laboratories and, furthermore, lack the flexibility to fulfill certain user-specific requirements. We have developed a Python module, screening_mgmt, which is a lightweight tool for flexible data retrieval, analysis, and storage for different screening assays in one central database. The module reads custom-made analysis scripts and plotting instructions, and it offers a graphical user interface to import, modify, and display the data in a uniform manner. During the test phase, we used this module for the management of 10,000 data points of various origins. It has provided a practical, user-friendly tool for sharing and exchanging information between researchers.

  11. Nutritional Screening of Children: A Manual for Screening & Followup.

    Science.gov (United States)

    Bureau of Community Health Services (DHHS/PHS), Rockville, MD.

    This manual shows health providers how to perform precisely and expertly each step of several procedures used in screening children for nutritional problems. It is intended for all health providers who are involved in weighing and measuring children, recording and plotting measurements on growth charts, taking blood samples to test for iron…

  12. Wastewater washing screens out solids

    Energy Technology Data Exchange (ETDEWEB)

    Mitchell, D.G. [Hycor Corp., Lake Bluff, IL (United States)

    1994-09-01

    Screening, as practiced by most municipal wastewater treatment plants, involves the manual or mechanical separation of all undesirable solids that flow into the sewer system. This consists of putresible or rotting material and inert solids such as paper, food, leaves, plastics, rubber, rocks, glass, metal and cigarette butts. These constituents, if not removed, clog downstream equipment and put a heavy load on aeration basins, dissolved air flotation equipment and digesters. Screenings washing is just entering the U.S. market with numerous benefits including increased efficiency, economics, safer work environment, and the ability to meet more stringent regulations.

  13. Gestational Diabetes Screening During Pregnancy

    Directory of Open Access Journals (Sweden)

    Cihan Cetin

    2015-09-01

    Full Text Available Gestational diabetes is a type of diabetes that is diagnosed during pregnancy in patients who do not have pregestational diabetes. Unless diagnosed and treated on time, it may cause various maternal, fetal and neonatal complications like macrosomia, polyhydramniosis, preterm labor, in utero ex fetus, infections, neonatal metabolic complications. The diagnosis of gestational diabetes stands on single-step or two-step screening/diagnosis strategies. These screening and diagnosis tests should be well known by physicians who are taking care of pregnants. [Archives Medical Review Journal 2015; 24(3.000: 348-354

  14. Risks of Ovarian, Fallopian Tube, and Primary Peritoneal Cancer Screening

    Science.gov (United States)

    ... Screening Research Ovarian, Fallopian Tube, and Primary Peritoneal Cancer Screening (PDQ®)–Patient Version What is screening? Go to ... ovarian cancer. Ovarian, Fallopian Tube, and Primary Peritoneal Cancer Screening Key Points Tests are used to screen for ...

  15. Ovarian, Fallopian Tube, and Primary Peritoneal Cancer Screening

    Science.gov (United States)

    ... Screening Research Ovarian, Fallopian Tube, and Primary Peritoneal Cancer Screening (PDQ®)–Patient Version What is screening? Go to ... ovarian cancer. Ovarian, Fallopian Tube, and Primary Peritoneal Cancer Screening Key Points Tests are used to screen for ...

  16. Iterative Cellular Screening System for Nanoparticle Safety Testing

    Directory of Open Access Journals (Sweden)

    Franziska Sambale

    2015-01-01

    Full Text Available Nanoparticles have the potential to exhibit risks to human beings and to the environment; due to the wide applications of nanoproducts, extensive risk management must not be neglected. Therefore, we have constructed a cell-based, iterative screening system to examine a variety of nanoproducts concerning their toxicity during development. The sensitivity and application of various cell-based methods were discussed and proven by applying the screening to two different nanoparticles: zinc oxide and titanium dioxide nanoparticles. They were used as benchmarks to set up our methods and to examine their effects on mammalian cell lines. Different biological processes such as cell viability, gene expression of interleukin-8 and heat shock protein 70, as well as morphology changes were investigated. Within our screening system, both nanoparticle suspensions and coatings can be tested. Electric cell impedance measurements revealed to be a good method for online monitoring of cellular behavior. The implementation of three-dimensional cell culture is essential to better mimic in vivo conditions. In conclusion, our screening system is highly efficient, cost minimizing, and reduces the need for animal studies.

  17. New Molecular Tools for Efficient Screening of Cervical Cancer

    Directory of Open Access Journals (Sweden)

    Magnus von Knebel Doeberitz

    2001-01-01

    Full Text Available Cytological screening using the Pap-smear led to a remarkable reduction of the mortality of cervical cancer. However, due to subjective test criteria it is hampered by poor inter- and intra-observer agreement. More reproducible assays are expected to improve the current screening and avoid unnecessary medical intervention and psychological distress for the affected women. Cervical cancer arises as consequence of persistent high risk papillomavirus (HR-HPV infections. Expression of two viral oncogenes, E6 and E7, in epithelial stem cells is required to initiate and maintain cervical carcinogenesis and results in significant overexpression of the cellular p16INK4a protein. Since this protein is not expressed in normal cervical squamous epithelia, screening for p16INK4a over-expressing cells allows to specifically identify dysplastic lesions, and significantly reduces the inter-observer disagreement of the conventional cytological or histological tests. Progression of preneoplastic lesions to invasive cancers is associated with extensive recombination of viral and cellular genomes which can be monitored by detection of papillomavirus oncogene transcripts (APOT assay derived from integrated viral genome copies. Detection of integrated type oncogene transcripts points to far advanced dysplasia or invasive cancers and thus represents a progression marker for cervical lesions. These new assays discussed here will help to improve current limitations in cervical cancer screening, diagnosis, and therapy control.

  18. [Emission of electromagnetic radiation from selected computer monitors].

    Science.gov (United States)

    Zyss, T

    1995-01-01

    The emission of electromagnetic fields from computer monitors was analysed. The data were compared with the permissible exposure level. EM radiation of chromatic monitors is higher than that of monochromatic ones. The radiation of magnetic fraction is insignificant. Both electric and magnetic fractions of EM radiation, 50 cm away from the monitor, are very low and do not exceed permissible values. It was observed that screen filters were effective in suppressing EM emission only at a short (up to 30 cm) distance from the monitor. At a distance of 50 cm they proved to be ineffective. Metallic-net filters were more effective than glass filters in suppressing EM radiation. It seems that EM fields generated by computer monitors are not harmful to computer operators if the distance is kept in safe limits.

  19. Guidelines for screening, diagnosis and management of hemoglobinopathies

    Directory of Open Access Journals (Sweden)

    Kanjaksha Ghosh

    2014-01-01

    Full Text Available The β-thalassemias and sickle cell disorders are a major health burden in India. Diagnosis and management of these disorders both in adults and in newborns using appropriate approaches and uniform technology are important in different regions of a vast and diverse country as India. In view of a National Thalassemia Control Program to be launched soon, a need was felt for guidelines on whom to screen, cost-effective technologies that are to be used as well as for establishing prenatal diagnosis programs in regional centers. Newborn screening for sickle cell disorders is in its infancy in India and uniform approaches need to be followed. Also, included are guidelines for monitoring and managing patients who are now growing older and need comprehensive care as well as management of complications of the disease.

  20. INDUSTRIAL/MILITARY ACTIVITY-INITIATED ACCIDENT SCREENING ANALYSIS

    Energy Technology Data Exchange (ETDEWEB)

    D.A. Kalinich

    1999-09-27

    Impacts due to nearby installations and operations were determined in the Preliminary MGDS Hazards Analysis (CRWMS M&O 1996) to be potentially applicable to the proposed repository at Yucca Mountain. This determination was conservatively based on limited knowledge of the potential activities ongoing on or off the Nevada Test Site (NTS). It is intended that the Industrial/Military Activity-Initiated Accident Screening Analysis provided herein will meet the requirements of the ''Standard Review Plan for the Review of Safety Analysis Reports for Nuclear Power Plants'' (NRC 1987) in establishing whether this external event can be screened from further consideration or must be included as a design basis event (DBE) in the development of accident scenarios for the Monitored Geologic Repository (MGR). This analysis only considers issues related to preclosure radiological safety. Issues important to waste isolation as related to impact from nearby installations will be covered in the MGR performance assessment.

  1. Can YAG screen accept LEReC bunch train?

    Energy Technology Data Exchange (ETDEWEB)

    Seletskiy S.; Thieberger, P.; Miller, T.

    2016-05-18

    LEReC RF diagnostic beamline is supposed to accept 250 us long pulse trains of 1.6 MeV – 2.6 MeV (kinetic energy) electrons. This beamline is equipped with YAG profile monitor. Since we are interested in observing only the last macro bunch in the train, one of the possibilities is to install a fast kicker and a dedicated dump upstream of the YAG screen (and related diagnostics equipment). This approach is expensive and challenging from engineering point of view. Another possibility is to send the whole pulse train to the YAG screen and to use a fast gated camera (such as Imperex B0610 with trigger jitter under 60ns) to observe the image from the last pulse only. In this paper we study the feasibility of the last approach.

  2. Care of Patients With HIV Infection: Diagnosis and Monitoring.

    Science.gov (United States)

    Bolduc, Philip; Roder, Navid; Colgate, Emily; Cheeseman, Sarah H

    2016-04-01

    Appropriate screening for HIV infection is the cornerstone of HIV-related care. There have been several recent changes in testing technology and screening recommendations. The US Preventive Services Task Force recommends universal HIV screening at least once for adolescents and adults ages 15 to 65 years, and additional screening for patients at higher risk, although evidence is insufficient to determine optimum rescreening intervals. All pregnant women should be screened for HIV infection in the first trimester, and pregnant women at high risk should be screened again in the third trimester. The Centers for Disease Control and Prevention recommends use of an algorithm using fourth-generation tests for screening; this decreases the window period between infection and detection to as few as 14 days, thereby reducing the number of false-negative results. Home HIV testing kits, which require follow-up confirmatory testing, also are available. Clinicians should be aware of HIV-specific laws in their states, including those criminalizing HIV exposure and transmission. Thorough medical and laboratory evaluations are essential at initiation of care for patients with HIV infection, along with appropriate follow-up monitoring, as recommended in various guidelines.

  3. Autism: definition, neurobiology, screening, diagnosis.

    Science.gov (United States)

    Rapin, Isabelle; Tuchman, Roberto F

    2008-10-01

    Autism (ie, the autism spectrum disorders) is now recognized in 1 in 150 children. This article highlights the definition, neurobiology, screening, and diagnosis of autism. The genetics, immunology, imaging, and neurophysiology of autism are reviewed, with particular emphasis on areas that impact pediatricians. Early recognition of the social deficits that characterize autism is key to maximizing the potential of these children.

  4. Urban Screen and Spatial Dimension

    Directory of Open Access Journals (Sweden)

    Litta Primasari

    2013-11-01

    Full Text Available This paper is discussing about the urban screen phenomena and its influence to spatial dimension in urban space. The visual characteristics which are forming a spatial dimension will be an emphasis to be presented. Urban screen as a visual intervention has an impact to spatial configuration in urban space. The space dimension was not dominated with materiality limitation, but also images. We have to consider that people senses can measure a spatial dimension, knowing as a perception. That is a human visual and mind relation. The spatial dimension has no longer tangible boundary, but also has intangible ones. Spatial dimension in urban screens phenomena is not merely mathematics, nor spatial dimension in physics which are based on a three-dimensional Cartesian coordinate system. Movement can be expressed in other terms, by how far we can move depends on our eyes to catch that space limitation, and how fast we can move is depends on our mind to perceive some visual phenomenon, that is a spatial dimension. So, the dimension will depend on a visual quality that we perceived. The movement of the body and people’s thought will be an important term to generate the space dimension in urban screen phenomenon. The activity of body’s movement and thought will influence the depth of space dimension.

  5. Radiative screening of fifth forces

    CERN Document Server

    Burrage, Clare; Millington, Peter

    2016-01-01

    We describe a symmetron model in which the screening of fifth forces arises at the one-loop level through the Coleman-Weinberg mechanism of spontaneous symmetry breaking. We show that such a theory can avoid current constraints on the existence of fifth forces, but still has the potential to give rise to observable deviations from general relativity.

  6. Colorectal Cancer Awareness and Screening

    Centers for Disease Control (CDC) Podcasts

    2017-04-06

    An oncologist (cancer doctor) shares her medical and personal advice for people between the ages of 50 and 75 about getting screened for colorectal cancer.  Created: 4/6/2017 by National Center for Chronic Disease Prevention and Health Promotion (NCCDPHP).   Date Released: 4/6/2017.

  7. Screening for Chronic Kidney Disease

    Science.gov (United States)

    ... screening. The Task Force did find evidence that medications used to treat early CKD may have harmful side effects in some people, such as cough, edema (swelling from fluid build-up), and heart problems. August 2012 Task Force FINAL Recommendation | 1 ...

  8. Population screening in hereditary hemochromatosis.

    Science.gov (United States)

    Motulsky, A G; Beutler, E

    2000-01-01

    Hemochromatosis is a common autosomal recessive condition found in the homozygous state in 1/200-1/400 people of northern-, central-, and western-European origin. It causes increased iron storage, which may lead to liver cirrhosis, liver cancer, heart disease, arthritis, and diabetes in many but not all affected adults, with a higher frequency in males. The condition is easily treated by repeated venesections without side effects but is frequently overlooked. Population screening of adults using iron indices alone or combined with DNA testing has therefore been recommended, but a consensus conference in 1997 recommended that such screening be deferred, owing to uncertainty regarding the extent of clinical disease that may develop in individuals detected by such programs. There was also concern that DNA screening results might be used for discrimination in insurance and occupational settings. Screening family members of patients with evidence of definite iron loading, however, is accepted by all observers. Because serious complications may be overlooked, a more aggressive stance toward case detection in the adult population has been advocated by some observers, realizing that unnecessary treatment might occur. Because additional information regarding the spectrum of clinical disease in homozygotes in now accumulating, a consensus conference in the near future is suggested to consider appropriate policies.

  9. Review of Autism Screening Tests

    Directory of Open Access Journals (Sweden)

    Farin Soleimani

    2014-10-01

    Full Text Available Background: Autism is a neurodevelopmental disorder that onset in the first 3 years of life and led to lifelong disability.Despite the early onset of symptoms, diagnosis of thissyndromedoes not happenuntil severalyears later, somany childrenlosethe opportunityfor earlyintervention.There arevarious toolsforscreening anddiagnosis, buttheirdesign, strengths and weaknesses aredifferent. The aim of this study was assess these tools from various aspects to provide a comprehensive view. Materials and methods: This study is a narrative literature review on screeningtoolsof autism. Comprehensive searches of the scientific literature were conducted in textbooks and 8 electronic databases(proquest,wiley,google scholar,SID,Scopus, Web of Science ،Science Direct ، and Medline and Pediatric book. language restriction (Persian and English was applied. The search strategy consisted of keywords and medical subject headings for autism and various screening tests. Result: In this study, 28 screening tests were identified from 1992 to 2014. CHAT is oldest test and the most recent test is CAST The minimum age that can perform the screening is six months that related to ITC. Minimum time of testing was 5 minutes  for CHAT and the maximum time was 90-120 minutes for ASIEP-3.RAADS-R test was the highest specificity and specificity (100% and the lowest specificity was 14% in ESAT test Conclusion: The results of this study indicate that any of the autism screening tools consider specific skill and various aspects of the disease, careful evaluation is need to choose proper test.

  10. Newborn screening for MCAD deficiency

    DEFF Research Database (Denmark)

    Horvath, Gabriella A; Davidson, A G F; Stockler-Ipsiroglu, Sylvia G

    2008-01-01

    BACKGROUND: Medium Chain Acyl-CoA Dehydrogenase (MCAD) Deficiency is an autosomal recessive disorder of fatty acid oxidation, with potential fatal outcome. MCAD deficiency is diagnosed by acylcarnitine analysis on newborn screening blood spot cards by tandem mass spectrometry. Early diagnosis of ...

  11. Chemical compatibility screening test results

    Energy Technology Data Exchange (ETDEWEB)

    Nigrey, P.J.; Dickens, T.G.

    1997-12-01

    A program for evaluating packaging components that may be used in transporting mixed-waste forms has been developed and the first phase has been completed. This effort involved the screening of ten plastic materials in four simulant mixed-waste types. These plastics were butadiene-acrylonitrile copolymer rubber, cross-linked polyethylene (XLPE), epichlorohydrin rubber, ethylene-propylene rubber (EPDM), fluorocarbon (Viton or Kel-F), polytetrafluoroethylene, high-density polyethylene (HDPE), isobutylene-isoprene copolymer rubber (butyl), polypropylene, and styrene-butadiene rubber (SBR). The selected simulant mixed wastes were (1) an aqueous alkaline mixture of sodium nitrate and sodium nitrite; (2) a chlorinated hydrocarbon mixture; (3) a simulant liquid scintillation fluid; and (4) a mixture of ketones. The testing protocol involved exposing the respective materials to 286,000 rads of gamma radiation followed by 14-day exposures to the waste types at 60{degrees}C. The seal materials were tested using vapor transport rate (VTR) measurements while the liner materials were tested using specific gravity as a metric. For these tests, a screening criterion of 0.9 g/hr/m{sup 2} for VTR and a specific gravity change of 10% was used. Based on this work, it was concluded that while all seal materials passed exposure to the aqueous simulant mixed waste, EPDM and SBR had the lowest VTRs. In the chlorinated hydrocarbon simulant mixed waste, only Viton passed the screening tests. In both the simulant scintillation fluid mixed waste and the ketone mixture simulant mixed waste, none of the seal materials met the screening criteria. For specific gravity testing of liner materials, the data showed that while all materials with the exception of polypropylene passed the screening criteria, Kel-F, HDPE, and XLPE offered the greatest resistance to the combination of radiation and chemicals.

  12. SCREENING FOR DIABETES IN PREGNANCY

    Directory of Open Access Journals (Sweden)

    Vidya Manoj

    2015-09-01

    Full Text Available AIM: All pregnant women are screened for gestational diabetes mellitus during pregnancy with timely intervention to reduce perinatal morbidity and obstetrics complication. OBJECTIVES: To determine the proportion of diabetes in ANC mother attending ANC OPD at Bh arati Hospital, to evaluate the high risk factor causing abnormal GTT and to evaluate outcome of pregnant mother with GDM. METHODS/STUDY DESIGN: The prospective study was conducted in 100 pregnant women attending antenatal checkup who had no previous histo ry of diabetes. ANC mothers were given 75gm glucose irrespective of last meal. A venous sample was collected at 2hr for estimating plasma glucose. Gestational Diabetes Mellitus was diagnosed if 2hrs . plasma glucose levels came >140mg/dl. RESULT AND CONCLUS ION : The screening of pregnant woman for diabetes on their first visit to antenatal clinic can be an effective method in detection of diabetes during pregnancy. Though the higher incidence is found in the risk group women in comparison to non - risk group, u niversal screening can be recommended instead of selective screening. Early screening does help in early detection of diabetes. Chances of gestational diabetes are increasing with increase in age & gravidity. Increasing maternal carbohydrate intolerance in pregnant women is associated with a graded increase in adverse maternal and fetal outcome. Women diagnosed to have GDM are at increased risk of future diabetes predominantly type 2 DM as are their children. Thus GDM offers an important opportunity for the development, testing and implementation of clinical strategies for diabetes prevention and reducing perinatal morbidity and obstetrics complications.

  13. What monitor can replace the cathode-ray tube for visual stimulation to elicit multifocal electroretinograms?

    Science.gov (United States)

    Matsumoto, Celso Soiti; Shinoda, Kei; Matsumoto, Harue; Seki, Keisuke; Nagasaka, Eiichiro; Iwata, Takeshi; Mizota, Atsushi

    2014-08-05

    To compare a conventional cathode-ray tube (CRT) screen to organic light-emitting diode (OLED) and liquid crystal display (LCD) screens as visual stimulators to elicit multifocal electroretinograms (mfERGs), mfERGs were recorded from seven eyes of seven healthy volunteers (21 ± 2 years). The mfERGs elicited by a conventional CRT screen (S710, Compaq Computer Co.) were compared to those elicited by a studio-grade master OLED monitor (PVM-1741, Sony, Japan) and a conventional LCD (S1721, Flexscan, Eizo Nanao Corp., Japan). The luminance changes of each monitor were measured with a photodiode. CRT, OLED, and LCD screens with a frame frequency of 60 Hz were studied. A hexagonal stimulus array with 61 stimulus elements was created on each monitor. The serial white stimuli of the OLED screen at 60 Hz did not fuse, and that of the LCD screens fused. The amplitudes of P1 and P2 of the first-order kernels of the mfERGs were not significantly different from those elicited by the CRT and OLED screens, and the P1 amplitude of the first-order kernel elicited by the LCD stimuli was significantly smaller than that elicited by the CRT in all the groups of the averaged hexagonal elements. The implicit times were approximately 10 ms longer in almost all components elicited by the LCD screen compared to those elicited by the CRT screen. The mfERGs elicited by monitors other than the CRT should be carefully interpreted, especially those elicited by LCD screens. The OLED had good performance, and we conclude that it can replace the CRT as a stimulator for mfERGs; however, a collection of normative data is recommended. © 2014 ARVO.

  14. Contamination during 4 years of annual CT screening in the Danish Lung Cancer Screening Trial (DLCST)

    DEFF Research Database (Denmark)

    Saghir, Zaigham; Ashraf, Haseem; Dirksen, Asger

    2010-01-01

    Contamination, defined as screening in the control arm, may dilute the statistical power of randomised screening trials. We investigated the rate of contamination in DLCST during 4 years of annual CT screening.......Contamination, defined as screening in the control arm, may dilute the statistical power of randomised screening trials. We investigated the rate of contamination in DLCST during 4 years of annual CT screening....

  15. Application of Sweat Patch Screening for 16 Drugs and Metabolites Using a Fast and Highly Selective LC-MS/MS Method

    NARCIS (Netherlands)

    Koster, Remco A.; Alffenaar, Jan-Willem C.; Greijdanus, Ben; VanDerNagel, Joanneke E. L.; Uges, Donald R. A.

    Background: To facilitate the monitoring of drug abuse by patients, a method was developed and validated for fast and highly selective screening for amphetamine, methamphetamine, 3,4-methylenedioxymethamphetamine, methylenedioxyamphetamine, methylenedioxyethylamphetamine, methylphenidate, cocaine,

  16. Application of Sweat Patch Screening for 16 Drugs and Metabolites Using a Fast and Highly Selective LC-MS/MS Method

    NARCIS (Netherlands)

    Koster, Remco A.; Alffenaar, Jan-Willem C.; Greijdanus, Ben; VanDerNagel, Joanneke E. L.; Uges, Donald R. A.

    2014-01-01

    Background: To facilitate the monitoring of drug abuse by patients, a method was developed and validated for fast and highly selective screening for amphetamine, methamphetamine, 3,4-methylenedioxymethamphetamine, methylenedioxyamphetamine, methylenedioxyethylamphetamine, methylphenidate, cocaine, b

  17. A distributed computing tool for generating neural simulation databases.

    Science.gov (United States)

    Calin-Jageman, Robert J; Katz, Paul S

    2006-12-01

    After developing a model neuron or network, it is important to systematically explore its behavior across a wide range of parameter values or experimental conditions, or both. However, compiling a very large set of simulation runs is challenging because it typically requires both access to and expertise with high-performance computing facilities. To lower the barrier for large-scale model analysis, we have developed NeuronPM, a client/server application that creates a "screen-saver" cluster for running simulations in NEURON (Hines & Carnevale, 1997). NeuronPM provides a user-friendly way to use existing computing resources to catalog the performance of a neural simulation across a wide range of parameter values and experimental conditions. The NeuronPM client is a Windows-based screen saver, and the NeuronPM server can be hosted on any Apache/PHP/MySQL server. During idle time, the client retrieves model files and work assignments from the server, invokes NEURON to run the simulation, and returns results to the server. Administrative panels make it simple to upload model files, define the parameters and conditions to vary, and then monitor client status and work progress. NeuronPM is open-source freeware and is available for download at http://neuronpm.homeip.net . It is a useful entry-level tool for systematically analyzing complex neuron and network simulations.

  18. Smoking cessation and lung cancer screening

    DEFF Research Database (Denmark)

    Pedersen, Jesper Holst; Tønnesen, Philip; Ashraf, Haseem

    2016-01-01

    Smoking behavior may have a substantial influence on the overall effect of lung cancer screening. Non-randomized studies of smoking behavior during screening have indicated that computer tomography (CT) screening induces smoking cessation. Randomized studies have further elaborated that this effect...... and decrease smoking relapse rate. Also low smoking dependency and high motivation to quit smoking at baseline predicted smoking abstinence in screening trials. Lung cancer screening therefore seems to be a teachable moment for smoking cessation. Targeted smoking cessation counselling should be an integrated...... part of future lung cancer screening trials....

  19. Radioactive contamination monitoring for the Korean public following Fukushima nuclear accident.

    Science.gov (United States)

    Ha, Wi-Ho; Yoo, Jaeryong; Yoon, Seokwon; Pak, Min-Jeong; Park, Seyong; Kim, Mi-Ryeong; Lee, Seung-Sook

    2013-11-01

    On March 11, 2011, as a result of the Great East Japan Earthquake, severe damage to the Fukushima nuclear power plant caused the release of radioactive materials. We conducted radioactive contamination monitoring for Korean residents in Japan and Korean travelers to East Japan after the accident. More than 800 members of the Korean public were surveyed for personal monitoring. Measured levels of external and internal contamination were within the screening levels for each monitoring method.

  20. Sky monitoring with LOBSTER

    Science.gov (United States)

    Hudec, R.; Tichy, V.

    2014-12-01

    The X--ray sky monitoring represents valuable energy spectral extension to optical sky monitoring. Lobster--Eye all--sky monitors are able to provide relatively high sensitivity and good time resolution in the soft X--ray energy range up to 10 keV. The fine time resolution can be used to alert optical robotic telescopes for follow--up and multispectral analyzes in the visible light.

  1. Loads Monitoring and Hums

    Science.gov (United States)

    2001-03-01

    Strain Measurement Fibre Optic Strain Temperature Pressure Crack Gage Crack Growth Accelerometer C.G. or Local Acceleration, Vibration, Buffet Pressure...Fig. 3.3-3 Zone 4 sensor location and results 1-15 A different method of monitoring structural health is shown in Fig. 3.3-4, a fibre optic array...Computer System Fig. 3.3-4 Fibre Optic monitoring array embedded in structure The two major tasks of structural health monitoring: Identification of

  2. Multiplex Screening of Persistent Organic Pollutants in Fish Using Spectrally Encoded Microspheres

    NARCIS (Netherlands)

    Meimaridou, A.; Kalachova, K.; Shelver, W.L.; Franek, M.; Pulkrabova, J.; Haasnoot, W.; Nielen, M.W.F.

    2011-01-01

    Persistent organic pollutants (POPs) are environmental and food-related contaminants of global public health concern and known to be carcinogenic and endocrine disruptors. Their monitoring is essential, and an easy-to-use, rapid, and affordable multianalyte screening method with simplified sample

  3. Multiplex screening of persistent organic pollutants in fish using spectrally encoded microspheres

    Science.gov (United States)

    Persistent organic pollutants (POPs) are food contaminants of global public health concern and known to be carcinogenic and endocrine disruptors. Their monitoring is essential and an easy-to-use, rapid and affordable multi-analyte screening method with simplified sample preparation can be a valuable...

  4. Microbial screening methods for detection of antibiotic residues in slaughter animals

    NARCIS (Netherlands)

    Pikkemaat, M.G.

    2009-01-01

    Monitoring of food products from animal origin for the presence of antimicrobial residues is preferably done using microbial screening methods because of their high cost-effectiveness. Traditionally applied methods fail to detect the maximum residue limits which were established when EU Council Regu

  5. Screening of Danish traffic cases for synthetic cannabinoids in whole blood by LC-MS/MS

    DEFF Research Database (Denmark)

    Holm, Niels Bjerre; Pineda, Rebeca; Andersen, David Wederkinck;

    2013-01-01

    transitions in multiple reaction monitoring mode. The limit of detection was between 0.1-2.5 ng/mL for the compounds except HU-210, and extraction recovery ranged from 59 to 78%. The method was used to screen 393 Danish traffic cases from 2012, where the driver was suspected of driving under the influence...

  6. EPICOG-SCH: A brief battery to screen cognitive impact of schizophrenia in stable outpatients

    Directory of Open Access Journals (Sweden)

    Silvia Zaragoza Domingo

    2017-06-01

    The EPICOG-SCH proved to be a useful brief tool to screen for the cognitive impact of schizophrenia, and its regression-weighted Composite Score was an efficient complement to clinical interviews for confirming patients' potential functional outcomes and can be useful for monitoring cognition during routine outpatient follow-up visits.

  7. Early sexual intercourse: Prospective associations with adolescents physical activity and screen time

    NARCIS (Netherlands)

    Avelar e Silva, R.N. (Raquel Nogueira); A.I. Wijtzes (Anne); Van De Bongardt, D. (Daphne); P.M. van de Looij-Jansen (Petra); R. Bannink (Rienke); H. Raat (Hein)

    2016-01-01

    textabstractObjectives: To assess the prospective associations of physical activity behaviors and screen time with early sexual intercourse initiation (i.e., before 15 years) in a large sample of adolescents. Methods: We used two waves of data from the Rotterdam Youth Monitor, a longitudinal study c

  8. Early sexual intercourse : Prospective associations with adolescents physical activity and screen time

    NARCIS (Netherlands)

    Nogueira Avelar e Silva, R.; Wijtzes, A.; van de Bongardt, D.; van de Looij-Jansen, P.; Bannink, R.; Raat, H.

    2016-01-01

    Objectives: To assess the prospective associations of physical activity behaviors and screen time with early sexual intercourse initiation (i.e., before 15 years) in a large sample of adolescents. Methods: We used two waves of data from the Rotterdam Youth Monitor, a longitudinal study conducted in

  9. Multiplex Screening of Persistent Organic Pollutants in Fish Using Spectrally Encoded Microspheres

    NARCIS (Netherlands)

    Meimaridou, A.; Kalachova, K.; Shelver, W.L.; Franek, M.; Pulkrabova, J.; Haasnoot, W.; Nielen, M.W.F.

    2011-01-01

    Persistent organic pollutants (POPs) are environmental and food-related contaminants of global public health concern and known to be carcinogenic and endocrine disruptors. Their monitoring is essential, and an easy-to-use, rapid, and affordable multianalyte screening method with simplified sample pr

  10. Supporting situational awareness through a patient overview screen for bipolar disorder treatment

    DEFF Research Database (Denmark)

    Frost, Mads; Gabrielli, Silvia

    2013-01-01

    Situational awareness, and how systems can be designed to support it, has been a focus in many dynamic, safety critical contexts, with great success. The work presented here extends the study of situation awareness into the domain of patient overview screens in personal monitoring systems...

  11. Supporting situational awareness through a patient overview screen for bipolar disorder treatment

    DEFF Research Database (Denmark)

    Frost, Mads; Gabrielli, Silvia

    2013-01-01

    . In this paper we report on the design and formative evaluation of a detailed patient overview screen for supporting the treatment of bipolar disorder through MONARCA, a personal monitoring system. We define the key items for supporting situational awareness for clinicians, as well as discuss key findings...

  12. [Chlamydia: from population screening to individual repeated screening].

    Science.gov (United States)

    Bally, F; Quach, A

    2014-10-08

    Chlamydia trachomatis is a frequent sexually transmitted infection especially in young adults and adolescents. Its complications can impair a woman's reproductive potential. chlamydia control has several challenges. These include asymptomatic infections; a long duration of untreated infections; re-infections and partner treatments. Any person with infection is at high risk of re-infection. Repeated screening would decrease, at an individual level, the risk of complications. General practitioners, gynaecologists and centres for sexual health could participate in Chlamydia screening for asymptomatic infections, in Switzerland, the cost of the laboratory test is fixed by national tariff regulations. The cost is high and prohibitive for many, especially adolescents and young adults and needs to be lowered.

  13. Monitoring of radiation exposure

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2000-02-01

    The guide specifies the requirements for the monitoring of radiation exposure in instances where radiation is used. In addition to workers, the guide covers students, apprentices and visitors. The guide shall also apply to exposure from natural radiation. However, the monitoring of radiation exposure in nuclear power plants is dealt with in YVL Guide 7.10 and 7.11. The guide defines the concepts relevant to the monitoring of radiation exposure and provides guidelines for determining the necessity of monitoring and subsequently arranging such in different operations. In addition, the guide specifies the criteria for the approval and regulatory control of the dosimetric service.

  14. Monitoring of radiation exposure

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2000-02-01

    The guide specifies the requirements for the monitoring of radiation exposure in instances where radiation is used. In addition to workers, the guide covers students, apprentices and visitors. The guide shall also apply to exposure from natural radiation. However, the monitoring of radiation exposure in nuclear power plants is dealt with in YVL Guide 7.10 and 7.11. The guide defines the concepts relevant to the monitoring of radiation exposure and provides guidelines for determining the necessity of monitoring and subsequently arranging such in different operations. In addition, the guide specifies the criteria for the approval and regulatory control of the dosimetric service.

  15. Environmental monitoring plan

    Energy Technology Data Exchange (ETDEWEB)

    Holland, R.C.

    1997-02-01

    This Environmental Monitoring Plan was written to fulfill the requirements of Department of Energy (DOE) Order 5400.1 and DOE Environmental Regulatory Guide DOE/EH 0173T. This Plan documents the background, organizational structure, and methods used for effluent monitoring and environmental surveillance at Sandia National Laboratories/California. The design, rationale, and historical results of the environmental monitoring system are discussed in detail. Throughout the Plan, recommendations for improvements to the monitoring system are made. 52 refs., 10 figs., 12 tabs.

  16. Remote Maintenance Monitoring System -

    Data.gov (United States)

    Department of Transportation — The Remote Maintenance and Monitoring System (RMMS) is a collection of subsystems that includes telecommunication components, hardware, and software, which serve to...

  17. Aerospace Systems Monitor Project

    Data.gov (United States)

    National Aeronautics and Space Administration — Proposal Title: Aerospace Systems Monitor PHASE 1 Technical Abstract: This Phase II STTR project will continue development and commercialization of the Aerospace...

  18. Network Monitoring with Nagios

    CERN Document Server

    Dondich, Taylor

    2006-01-01

    Network monitoring can be a complex task to implement and maintain in your IT infrastructure. Nagios, an open-source host, service and network monitoring program can help you streamline your network monitoring tasks and reduce the cost of operation.With this shortcut guide, we'll go over how Nagios fits in the overall network monitoring puzzle. We'll also cover installation and basic usage. Finally, we'll show you how to extend Nagios with other tools to extend functionality.

  19. IEEE 802.11 ECG monitoring system.

    Science.gov (United States)

    Tejero-Calado, Juan; Lopez-Casado, Carmen; Bernal-Martin, Antonio; Lopez-Gomez, Miguel; Romero-Romero, Marco; Quesada, Guillermo; Lorca, Julio; Rivas, Ramon

    2005-01-01

    New wireless technologies make possible the implementation of high level integration wireless devices which allow the replacement of traditional large wired monitoring devices. This kind of devices favours at-home hospitalization, reducing the affluence to sanitary assistance centers to make routine controls. This fact causes a really favourable social impact, especially for elder people, rural-zone inhabitant, chronic patients and handicapped people. Furthermore, it offers new functionalities to physicians and will reduce the sanitary cost. Among these functionalities, biomedical signals can be sent to other devices (screen, PDA, PC...) or processing centers, without restricting the patients' mobility. The aim of this project is the development and implementation of a reduced size multi-channel electrocardiograph based on IEEE 802.11, which allows wireless monitoring of patients, and the insertion of the information into the TCP/IP Hospital network.

  20. Augmented Fish Health Monitoring, 1987 Annual Report.

    Energy Technology Data Exchange (ETDEWEB)

    Michak, Patty

    1989-04-01

    Washington Department of Fisheries has divided the sampling and data collection into three major groups: adult analysis, juvenile analysis and database development. The adult analysis done at spawning includes screening for viral pathogens and Bacterial Kidney Disease (BKD). Pre-spawning mortalities are sampled for the presence of bacterial pathogens and parasites to determine causes of pre-spawning loss. Juvenile analysis involves monthly monitoring; pre-release examinations for viral pathogens, BKD and, where appropriate, whirling disease (M. cerebralis); completion of the Organosomatic analysis on four index stocks, and midterm exams on yearling groups for BKD and M. cerebralis. Database development required constructing fish health monitoring forms and a computer based data entry and retrieval system. We have completed a full year of sampling and data collection, January, 1987 to January, 1988. This report will present and analyze this information.

  1. Low-cost screening for microbial contaminants in aerosols generated in a dental office.

    Science.gov (United States)

    Hubar, J Sean; Pelon, William

    2005-01-01

    It has been reported that aerosols and droplets generated by high-speed dental drills and cavitrons are contaminated with blood and bacteria and represent a potential route for transmitting disease. Bacterial cells possess a negative electrical charge, while the cathode ray tubes (CRT) that are used in computer monitors generate positively charged static electric fields. Consequently, bacteria dispersed within these aerosols could be attracted to the screens on CRT monitors. In this study, pathogenic strains of Staphylococcus aureus were found on CRT screens in different locations within the Louisiana State University School of Dentistry facility. The results suggest that surveying CRT screens is a simple method for evaluating the airborne microbial contaminants present within a dental office.

  2. Microalgae biorefinery symbiosis: screening, production, and process analytical technology

    DEFF Research Database (Denmark)

    Podevin, Michael Paul Ambrose

    on these potential bioindustrial WW streams for their growth potential. During screening, microalgae may have a preference or aversion for a given bioindustrial WW media, based on the types and ratios of nitrogen (ammonium, nitrate, or urea) in the WW. Furthermore, identifying algae capable of withstanding...... and functional products, on top of biofuels in a biorefinery, there will be a growing need to maintain product quality, regulate, and mitigate contamination, especially in a symbiosis with WW. Vibrational spectroscopies can be used to monitor several microalgal components simultaneously, which can be used to aid...

  3. Linking high resolution mass spectrometry data with exposure and toxicity forecasts to advance high-throughput environmental monitoring

    Data.gov (United States)

    U.S. Environmental Protection Agency — There is a growing need in the field of exposure science for monitoring methods that rapidly screen environmental media for suspect contaminants. Measurement and...

  4. Method for detecting, screening and/or montoring a cancer in individual

    DEFF Research Database (Denmark)

    2005-01-01

    The invention relates to a method for screening and/or detecting and/or monitoring a cancer in an individual, said method comprising determining a first parameter represented by the concentration of TIMP-1 in at least one excreta, e.g. saliva, from the individual. The invention provides a method...... that without the need to use a blood sample is suitable for facilitating the early diagnosis of a cancer, monitoring the recurrence of a cancer, and/or monitoring the status of a cancer or the effect of cancer treatment in an individual....

  5. Adapting the Australian system: is an organized screening program feasible in Malaysia?--an overview of cervical cancer screening in both countries.

    Science.gov (United States)

    Rashid, Rima Ma; Dahlui, Maznah; Mohamed, Majdah; Gertig, Dorota

    2013-01-01

    Cervical cancer is the third most common form of cancer that strikes Malaysian women. The National Cancer Registry in 2006 and 2007 reported that the age standardized incidence (ASR) of cervical cancer was 12.2 and 7.8 per 100,000 women, respectively. The cumulative risk of developing cervical cancer for a Malaysian woman is 0.9 for 74 years. Among all ethnic groups, the Chinese experienced the highest incidence rate in 2006, followed by Indians and Malays. The percentage cervical cancer detected at stage I and II was 55% (stage I: 21.0%, stage II: 34.0%, stage III: 26.0% and stage IV: 19.0%). Data from Ministry of Health Malaysia (2006) showed a 58.9% estimated coverage of pap smear screening conducted among those aged 30-49 years. Only a small percentage of women aged 50-59 and 50-65 years old were screened, 14% and 13.8% coverage, respectively. Incidence of cervical cancer was highest (71.6%) among those in the 60-65 age group (MOH, 2003). Currently, there is no organized population-based screening program available for the whole of Malaysia. A pilot project was initiated in 2006, to move from opportunistic cervical screening of women who attend antenatal and postnatal visits to a population based approach to be able to monitor the women through the screening pathway and encourage women at highest risk to be screened. The project was modelled on the screening program in Australia with some modifications to suit the Malaysian setting. Substantial challenges have been identified, particularly in relation to information systems for call and recall of women, as well as laboratory reporting and quality assurance. A cost-effective locally-specific approach to organized screening, that will provide the infrastructure for increasing participation in the cervical cancer screening program, is urgently required.

  6. Electrochemical mutagen screening using microbial chip.

    Science.gov (United States)

    Matsui, Nobuto; Kaya, Takatoshi; Nagamine, Kuniaki; Yasukawa, Tomoyuki; Shiku, Hitoshi; Matsue, Tomokazu

    2006-01-15

    Electrochemical microbial chip for mutagen screening were microfabricated and characterized by scanning electrochemical microscopy (SECM). Salmonella typhimurium TA1535 with a plasmid pSK1002 carrying a umuC'-'lacZ fusion gene was used for the whole cell mutagen sensor. The TA1535/pSK1002 cells were exposed to mutagen solutions containing 2-(2-furyl)-3-(5-nitro-2-furyl)acrylamido (AF-2), mitomycin C (MMC) or 2-aminoanthracene (2-AA) and embedded in a microcavity (5nl) on a glass substrate using collagen gel. The beta-galactosidase expression on the microbial chip was electrochemically monitored using p-aminophenyl-beta-d-galactopyranoside (PAPG) as the enzymatic substrate. This system has several advantages compared with the conventional umu test: drastic reduction of the sample volume, less time-consuming for beta-galactosidase detection (free from substrate reaction time) and lower detection limit for the three mutagens (AF-2, MMC, 2-AA). Finally, a multi-sample assay was carried out using the microbial array chip with four microcavities.

  7. A Drosophila Model for Screening Antiobesity Agents

    Directory of Open Access Journals (Sweden)

    Tran Thanh Men

    2016-01-01

    Full Text Available Although triacylglycerol, the major component for lipid storage, is essential for normal physiology, its excessive accumulation causes obesity in adipose tissue and is associated with organ dysfunction in nonadipose tissue. Here, we focused on the Drosophila model to develop therapeutics for preventing obesity. The brummer (bmm gene in Drosophila melanogaster is known to be homologous with human adipocyte triglyceride lipase, which is related to the regulation of lipid storage. We established a Drosophila model for monitoring bmm expression by introducing the green fluorescent protein (GFP gene as a downstream reporter of the bmm promoter. The third-instar larvae of Drosophila showed the GFP signal in all tissues observed and specifically in the salivary gland nucleus. To confirm the relationship between bmm expression and obesity, the effect of oral administration of glucose diets on bmm promoter activity was analyzed. The Drosophila flies given high-glucose diets showed higher lipid contents, indicating the obesity phenotype; this was suggested by a weaker intensity of the GFP signal as well as reduced bmm mRNA expression. These results demonstrated that the transgenic Drosophila model established in this study is useful for screening antiobesity agents. We also report the effects of oral administration of histone deacetylase inhibitors and some vegetables on the bmm promoter activity.

  8. Capillary blood glucose screening for gestational diabetes: a preliminary investigation.

    Science.gov (United States)

    Landon, M B; Cembrowski, G S; Gabbe, S G

    1986-10-01

    Home glucose monitoring with the use of reflectance meters is an important adjunct in the care of pregnant women with insulin-dependent diabetes. The accuracy of reflectance meters for the assay of capillary glucose specimens has been well documented. The present preliminary study was undertaken to determine the utility of outpatient screening for gestational diabetes mellitus with the use of a reflectance meter (Accu-Chek, Boehringer Mannheim Co.). One hundred twenty-five patients in our high-risk practice had a standard 50 gm glucose load at 26 to 28 weeks' gestation. Capillary glucose values were measured on site with the Accu-Chek. Venous plasma glucose levels were measured by the central laboratory chemistry analyzer. While the laboratory (x) and meter (y) glucose determinations between the two sets of values were highly correlated (R = 0.89, p less than 0.001), there was a significant difference in their average values (x = 111.74, y = 136.35, p less than 0.0001). With the use of a receiver operator characteristic curve, a meter value of 160 mg/dl was determined as the optimal threshold for performing a 3-hour glucose tolerance test. The sensitivity and specificity with the use of a meter value of 160 mg/dl were 93% and 96%, respectively, for detecting an abnormal screening test in venous plasma (greater than or equal to 135 mg/dl). A total of 32 glucose tolerance tests were performed, with four patients included who had venous values less than 135 mg/dl. All eight patients with gestational diabetes mellitus were correctly identified. These data suggest that a glucose reflectance meter can be used for accurate outpatient screening of gestational diabetes mellitus. The potential advantages of capillary blood glucose screening include both cost and efficiency. Patients with abnormal screening values can be promptly identified and scheduled for a follow-up 3-hour glucose tolerance test.

  9. Screening and Management of Asymptomatic Renal Stones in Astronauts

    Science.gov (United States)

    Reyes, David; Locke, James; Sargsyan, Ashot; Garcia, Kathleen

    2017-01-01

    Management guidelines were created to screen and manage asymptomatic renal stones in U.S. astronauts. The true risk for renal stone formation in astronauts due to the space flight environment is unknown. Proper management of this condition is crucial to mitigate health and mission risks. The NASA Flight Medicine Clinic electronic medical record and the Lifetime Surveillance of Astronaut Health databases were reviewed. An extensive review of the literature and current aeromedical standards for the monitoring and management of renal stones was also done. This work was used to develop a screening and management protocol for renal stones in astronauts that is relevant to the spaceflight operational environment. In the proposed guidelines all astronauts receive a yearly screening and post-flight renal ultrasound using a novel ultrasound protocol. The ultrasound protocol uses a combination of factors, including: size, position, shadow, twinkle and dispersion properties to confirm the presence of a renal calcification. For mission-assigned astronauts, any positive ultrasound study is followed by a low-dose renal computed tomography scan and urologic consult. Other specific guidelines were also created. A small asymptomatic renal stone within the renal collecting system may become symptomatic at any time, and therefore affect launch and flight schedules, or cause incapacitation during a mission. Astronauts in need of definitive care can be evacuated from the International Space Station, but for deep space missions evacuation is impossible. The new screening and management algorithm has been implemented and the initial round of screening ultrasounds is under way. Data from these exams will better define the incidence of renal stones in U.S. astronauts, and will be used to inform risk mitigation for both short and long duration spaceflights.

  10. Screening and Management of Asymptomatic Renal Stones in Astronauts

    Science.gov (United States)

    Reyes, David; Locke, James; Sargsyan, Ashot; Garcia, Kathleen

    2017-01-01

    Management guidelines were created to screen and manage asymptomatic renal stones in U.S. astronauts. The true risk for renal stone formation in astronauts due to the space flight environment is unknown. Proper management of this condition is crucial to mitigate health and mission risks. The NASA Flight Medicine Clinic electronic medical record and the Lifetime Surveillance of Astronaut Health databases were reviewed. An extensive review of the literature and current aeromedical standards for the monitoring and management of renal stones was also done. This work was used to develop a screening and management protocol for renal stones in astronauts that is relevant to the spaceflight operational environment. In the proposed guidelines all astronauts receive a yearly screening and post-flight renal ultrasound using a novel ultrasound protocol. The ultrasound protocol uses a combination of factors, including: size, position, shadow, twinkle and dispersion properties to confirm the presence of a renal calcification. For mission-assigned astronauts, any positive ultrasound study is followed by a low-dose renal computed tomography scan and urologic consult. Other specific guidelines were also created. A small asymptomatic renal stone within the renal collecting system may become symptomatic at any time, and therefore affect launch and flight schedules, or cause incapacitation during a mission. Astronauts in need of definitive care can be evacuated from the International Space Station, but for deep space missions evacuation is impossible. The new screening and management algorithm has been implemented and the initial round of screening ultrasounds is under way. Data from these exams will better define the incidence of renal stones in U.S. astronauts, and will be used to inform risk mitigation for both short and long duration spaceflights.

  11. Screening Sex: revelando e dissimulando o sexo Screening Sex

    Directory of Open Access Journals (Sweden)

    Linda Williams

    2012-06-01

    Full Text Available Neste texto, procura-se contar a história da exibição do sexo em filmes majoritariamente produzidos nos Estados Unidos no período de quase um século. Ao se perguntar quando, porque e como os Estados Unidos se transformaram de uma cultura que não exibia o sexo em uma que o exibe, a autora insiste no duplo significado do verbo screen (tanto como uma revelação quanto uma dissimulação. Exibir é revelar em uma tela. Mas um segundo e igualmente importante significado, como diz o dicionário é "proteger ou esconder atrás de uma tela". Os filmes tanto revelam como escondem. O artigo analisa a forma como mudanças sociais ocorridas nos Estados Unidos, como, por exemplo, a Revolução sexual dos anos 60 e novas visões a respeito da sexualidade, possibilitaram novas maneiras de representação do sexo no cinema, reorganizando a relação entre o público e o privado. O artigo se pergunta também sobre como nossos corpos e sentidos reagem ao encontro com o sexo na tela, introduzindo a ideia de "saber carnal" (carnal knowledge.In this paper, we try to tell the history of the exhibition of sex in movies mainly produced in the United States in almost a century. Asking when, why and how the United States became - from a culture that did not exhibit sex - into a culture that exhibits it, the author insists in the double sense of the verb to screen (as both a revelation and a dissimulation. To exhibit is to reveal in a screen. But another, and important, sense, as says the dictionary, is "to protect or hide behind a screen". Movies show as well as they reveal. The paper analyzes the way social change in the United States, for example the sexual revolution of the sixties and new views on sexuality allowed new ways of representing sex in the movies, creating a new relation between public and private. The paper also asks how our bodies and senses react to sex in the screen, introducing the idea of "carnal knowledge".

  12. Screening and Early Detection - Cancer Currents Blog

    Science.gov (United States)

    A catalog of posts from NCI’s Cancer Currents blog on research related to cancer screening and early detection. Includes posts on diagnostic biomarkers and advances or trends in screening practices.

  13. Screening for Human Immunodeficiency Virus (HIV)

    Science.gov (United States)

    Understanding Task Force Recommendations Screening for Human Immunodeficiency Virus (HIV) The U.S. Preventive Services Task Force (Task Force) has issued a final recommendation statement on Screening for Human Immunodeficiency Virus (HIV) . ...

  14. Use of fluorescent screens for isotope radiography

    Energy Technology Data Exchange (ETDEWEB)

    Hubbard, S. K.

    1979-01-01

    Radiographic examination can be performed on items beyond the limitation of conventional isotope radiography without a great loss of resolution. With proper film and screen selection and scatter radiation control, fluorescent screens can be a valuable additional tool for radiography.

  15. Sites Pre-Screened for Wind Energy

    Data.gov (United States)

    U.S. Environmental Protection Agency — The RE-Powering Screening Dataset spreadsheet contains detailed site information on over 80,000 contaminated lands, landfills, and mine sites with screening results...

  16. Maximising benefit and minimising harm of screening

    OpenAIRE

    Gray, J A M; Patnick, J.; Blanks, R G

    2008-01-01

    Gordon Brown has pledged to increase screening services in the NHS. Muir Gray, Julietta Patnick, and Roger Blanks show how experience with the UK breast screening programme can help ensure that they are effective

  17. Screening for Cognitive Impairment in Older Adults

    Science.gov (United States)

    ... evidence to make a recommendation for or against screening all older adults for cognitive impairment. The Task Force recognizes that ... there was not enough evidence to determine whether screening all older adults would be beneficial. It therefore could not recommend ...

  18. Breast cancer screening: ''reassuring'' the worried well?

    DEFF Research Database (Denmark)

    Brodersen, John; Siersma, Volkert; Ryle, Mette

    2011-01-01

    of women offered screening compared to a population of women not offered screening for breast cancer. METHODS: One thousand women, aged 50-69 years, were randomly drawn from the Danish Civil Registration System to receive part I of the questionnaire Consequences of Screening in Breast Cancer (COS-BC1......): the sample consisted of 500 women living in a geographical area where screening mammography had been offered for more than 10 years and 500 women living in an area where the public health authorities had never invited women to breast cancer screening. RESULTS: A total of 759 women returned the questionnaire....... Those living in areas where screening was not offered reported more negative psychosocial aspects compared to women living in areas where screening was offered. CONCLUSIONS: The results indicate that women tend to perceive breast cancer screening as a reassuring preventive initiative. Alternatively...

  19. Does school scoliosis screening make the grade?

    Science.gov (United States)

    Jakubowski, Tami L; Alexy, Eileen M

    2014-09-01

    School nurses have provided routine health screenings of school-age children for decades. During the 1970s, recommendations for school scoliosis screening, which were based upon poor access to health care, led state boards of education to mandate that school nurses screen for scoliosis. The history of mandated scoliosis screening in U.S. schools is reviewed, and current school nurse practices for scoliosis screening are presented. Elevated referral rates for repeat scoliosis examination following school scoliosis screenings have led to questions of efficacy. Further controversy exists regarding school nurses screening for scoliosis due to a lack of evidence indicating a decreased need for scoliosis surgery. This article contains evidence-based recommendations for discontinuing school scoliosis screening to help school nurses refocus their efforts on complex health needs and preventive health issues more likely to impact the majority of their students.

  20. CDC Vital Signs: Alcohol Screening and Counseling

    Science.gov (United States)

    ... Read the MMWR Science Clips Alcohol Screening and Counseling An effective but underused health service Language: English ... about their drinking. 25% Alcohol screening and brief counseling can reduce the amount consumed on an occasion ...

  1. Dynamics Behavior Research on Variable Linear Vibration Screen with Flexible Screen Face

    Directory of Open Access Journals (Sweden)

    Changlong Du

    2014-08-01

    Full Text Available In order to enable the variable linear vibration screen with ideal movement behavior of screen surface and efficient screening capacity, five-freedom dynamic model and stability equations of the variable linear vibration screen were established based on power balance method and Hamilton principle. The motion behaviour of screen face was investigated, and − 0.10 m ≤ xf ≤ − 0.04 m was confirmed as the best range of exciting position. With analysis of stability equations, the stable requirement of vibration screen was obtained: the direction angle of exciting force should be 0 ≤ θ ≤ 45°. Screening processes of variable linear vibration screen with flexible screen face, variable linear vibration screen with fixed screen face and linear vibration screen were investigated and compared by numerical simulation method, the results show that variable linear vibration screen with flexible screen face have such characteristics as higher intensity of projection and efficient screening. The correctness of theoretical research and simulation research were verified through experiment, and all of the work would provide some guidance for designing and studying variable linear vibration screen with flexible screen face.

  2. 3D mosquito screens to create window double screen traps for mosquito control.

    Science.gov (United States)

    Khattab, Ayman; Jylhä, Kaisa; Hakala, Tomi; Aalto, Mikko; Malima, Robert; Kisinza, William; Honkala, Markku; Nousiainen, Pertti; Meri, Seppo

    2017-08-29

    Mosquitoes are vectors for many diseases such as malaria. Insecticide-treated bed nets and indoor residual spraying of insecticides are the principal malaria vector control tools used to prevent malaria in the tropics. Other interventions aim at reducing man-vector contact. For example, house screening provides additive or synergistic effects to other implemented measures. We used commercial screen materials made of polyester, polyethylene or polypropylene to design novel mosquito screens that provide remarkable additional benefits to those commonly used in house screening. The novel design is based on a double screen setup made of a screen with 3D geometric structures parallel to a commercial mosquito screen creating a trap between the two screens. Owing to the design of the 3D screen, mosquitoes can penetrate the 3D screen from one side but cannot return through the other side, making it a unidirectional mosquito screen. Therefore, the mosquitoes are trapped inside the double screen system. The permissiveness of both sides of the 3D screens for mosquitoes to pass through was tested in a wind tunnel using the insectary strain of Anopheles stephensi. Among twenty-five tested 3D screen designs, three designs from the cone, prism, or cylinder design groups were the most efficient in acting as unidirectional mosquito screens. The three cone-, prism-, and cylinder-based screens allowed, on average, 92, 75 and 64% of Anopheles stephensi mosquitoes released into the wind tunnel to penetrate the permissive side and 0, 0 and 6% of mosquitoes to escape through the non-permissive side, respectively. A cone-based 3D screen fulfilled the study objective. It allowed capturing 92% of mosquitoes within the double screen setup inside the wind tunnel and blocked 100% from escaping. Thus, the cone-based screen effectively acted as a unidirectional mosquito screen. This 3D screen-based trap design could therefore be used in house screening as a means of avoiding infective bites and

  3. Clad Degradation - FEPs Screening Arguments

    Energy Technology Data Exchange (ETDEWEB)

    E. Siegmann

    2004-03-17

    The purpose of this report is to document the screening of the cladding degradation features, events, and processes (FEPs) for commercial spent nuclear fuel (CSNF). This report also addresses the effect of some FEPs on both the cladding and the CSNF, DSNF, and HLW waste forms where it was considered appropriate to address the effects on both materials together. This report summarizes the work of others to screen clad degradation FEPs in a manner consistent with, and used in, the Total System Performance Assessment-License Application (TSPA-LA). This document was prepared according to ''Technical Work Plan for Waste Form Degradation Modeling, Testing, and Analyses in Support of LA'' (BSC 2004a [DIRS 167796]).

  4. Screening for autologous blood transfusions

    DEFF Research Database (Denmark)

    Mørkeberg, J; Belhage, B; Ashenden, M

    2009-01-01

    The ratio between the amount of hemoglobin in the mature erythrocyte population and the reticulocytes (RBCHb:RetHb ratio) has previously been suggested as a marker to screen for EPO-abuse. We speculated that the reinfusion of blood would lead to a marked increase in this ratio, making it a valuab...... doping after reinfusion, and the parameter could be used in a testing setting, once stability validation has been performed....... parameter in the screening for autologous blood doping. Three bags of blood (approximately 201+/-11 g of Hb) were withdrawn from 16 males and stored at either -80 degrees C (-80 T, n=8) or +4 degrees C (+4 T, n=8) and reinfused 10 weeks or 4 weeks later, respectively. Seven subjects served as controls...

  5. Tuberculosis screening in patients with HIV

    DEFF Research Database (Denmark)

    Bjerrum, Stephanie Mia Katrine; Bonsu, Frank; Hanson-Nortey, Nii Nortey

    2016-01-01

    BACKGROUND: Tuberculosis screening of people living with HIV (PLHIV) can contribute to early tuberculosis diagnosis and improved patient outcomes. Evidence-based guidelines for tuberculosis screening are available, but literature assessing their implementation and the quality of clinical practice...... is scarce. OBJECTIVES: To assess tuberculosis screening practices and the effectiveness of audit and performance feedback to improve quality of tuberculosis screening at HIV care clinics in Ghana. DESIGN: Healthcare providers at 10 large HIV care clinics prospectively registered patient consultations during...

  6. SCREENING FOR EARLY DETECTION OF BREAST CANCER

    Directory of Open Access Journals (Sweden)

    E. A. Rasskazova

    2014-01-01

    Full Text Available The article presents a brief overview of the main methods of breast cancer screening. Proven effectiveness of mammography as a screening method in reducing mortality from breast cancer, specified limits of the method. The main trend of increasing the effectiveness of screening is the transition to digital technologies. Properly organized screening with the active participation of the population reduces mortality from breast cancer by 30%.

  7. Water Quality Monitoring Manual.

    Science.gov (United States)

    Mason, Fred J.; Houdart, Joseph F.

    This manual is designed for students involved in environmental education programs dealing with water pollution problems. By establishing a network of Environmental Monitoring Stations within the educational system, four steps toward the prevention, control, and abatement of water pollution are proposed. (1) Train students to recognize, monitor,…

  8. Improved Marine Waters Monitoring

    Science.gov (United States)

    Palazov, Atanas; Yakushev, Evgeniy; Milkova, Tanya; Slabakova, Violeta; Hristova, Ognyana

    2017-04-01

    IMAMO - Improved Marine Waters Monitoring is a project under the Programme BG02: Improved monitoring of marine waters, managed by Bulgarian Ministry of environment and waters and co-financed by the Financial Mechanism of the European Economic Area (EEA FM) 2009 - 2014. Project Beneficiary is the Institute of oceanology - Bulgarian Academy of Sciences with two partners: Norwegian Institute for Water Research and Bulgarian Black Sea Basin Directorate. The Project aims to improve the monitoring capacity and expertise of the organizations responsible for marine waters monitoring in Bulgaria to meet the requirements of EU and national legislation. The main outcomes are to fill the gaps in information from the Initial assessment of the marine environment and to collect data to assess the current ecological status of marine waters including information as a base for revision of ecological targets established by the monitoring programme prepared in 2014 under Art. 11 of MSFD. Project activities are targeted to ensure data for Descriptors 5, 8 and 9. IMAMO aims to increase the institutional capacity of the Bulgarian partners related to the monitoring and assessment of the Black Sea environment. The main outputs are: establishment of real time monitoring and set up of accredited laboratory facilities for marine waters and sediments chemical analysis to ensure the ability of Bulgarian partners to monitor progress of subsequent measures undertaken.

  9. Strategic Tutor Monitoring.

    Science.gov (United States)

    Chee-kwong, Kenneth Chao

    1996-01-01

    Discusses effective tutor monitoring strategies based on experiences at the Open Learning Institute of Hong Kong. Highlights include key performance and strategic control points; situational factors, including tutor expectations and relevant culture; Theory X versus Theory Y leadership theories; and monitoring relationships with tutors. (LRW)

  10. Strategic Tutor Monitoring.

    Science.gov (United States)

    Chee-kwong, Kenneth Chao

    1996-01-01

    Discusses effective tutor monitoring strategies based on experiences at the Open Learning Institute of Hong Kong. Highlights include key performance and strategic control points; situational factors, including tutor expectations and relevant culture; Theory X versus Theory Y leadership theories; and monitoring relationships with tutors. (LRW)

  11. Mariene monitoring & Natura 2000

    NARCIS (Netherlands)

    Paijmans, A.J.; Asjes, J.

    2012-01-01

    IMARES heeft in opdracht van het ministerie van EL&I een rapport opgesteld over de eisen die de Habitatrichtlijn en de Vogelrichtlijn stellen ten aanzien van de monitoring in de Nederlandse zoute wateren. Vervolgens is geanalyseerd waar de huidige monitoring die wordt uitgevoerd voldoet aan deze

  12. Global nuclear material monitoring

    Energy Technology Data Exchange (ETDEWEB)

    Howell, J.A.; Monlove, H.O.; Goulding, C.A.; Martinez, B.J.; Coulter, C.A.

    1997-08-01

    This is the final report of a one-year Laboratory-Directed Research and Development (LDRD) project at the Los Alamos National Laboratory (LANL). This project provided a detailed systems design for advanced integrated facility monitoring and identified the components and enabling technologies required to facilitate the development of the monitoring system of the future.

  13. Facility effluent monitoring

    Energy Technology Data Exchange (ETDEWEB)

    Gleckler, B.P.

    1995-06-01

    This section of the 1994 Hanford Site Environmental Report summarizes the facility effluent monitoring programs and provides an evaluation of effluent monitoring data. These evaluations are useful in assessing the effectiveness of effluent treatment and control systems, as well as management practices.

  14. Osteoporosis screening and risk management

    OpenAIRE

    Wilkins, Consuelo H.

    2007-01-01

    Consuelo H WilkinsDepartment of Medicine, Division of Geriatrics and Nutritional Science, Washington University School of Medicine, St. Louis, MO, USAAbstract: Osteoporosis is common among older adults and results in costly osteoporotic fractures. Screening for this metabolic bone disorder is warranted in most older adults and clinicians must be diligent in identifying persons at risk. The evaluation should include an assessment of risk factors for falls, a bone density test, and consideratio...

  15. Computer Screen or Real Life?

    DEFF Research Database (Denmark)

    Suurmets, Seidi; Clement, Jesper

    Aims: In many disciplines, including consumer and marketing research, the findings from eyetracking studies in lab settings are often generalized to natural environments. While studies in the real world have become more common with a statement on increased external validity, the degree to which t...... and consumer research this study uncovers the distortions in visual attention that result from reducing a threedimensional setting into a twodimensional screen image....

  16. Screening in quantum charged systems

    Science.gov (United States)

    Martin, Ph. A.; Gruber, Ch.

    1984-07-01

    For stationary states of quantum charged systems in ν dimensions, ν>=2, it is proven that the reduced-density matrices satisfy a set of sum rules whenever the clustering is faster than |x|-(ν+l). These sum rules, describing the screening properties, are analogous to those previously derived for classical systems. For neutral quantum fluids, it is shown that the clustering cannot be faster than the decay of the force.

  17. Reaction screening using a microreactor.

    Science.gov (United States)

    Naef, Olivier; Roch, Mathieu; Chappuis, Thierry

    2010-01-01

    This article discusses the screening of chemical reactions using a microreactor equipped with infrared spectroscopy as online analytics. An esterification reaction has been optimized in continuous mode with the proposed setup. The esterification did not work well due to the material of the microreactor (stainless-steel 316Ti) that catalyzed the decomposition of formic acid. However, despite the occurrence of decomposition, an optimization could be achieved with this system.

  18. Celebrity endorsements of cancer screening.

    Science.gov (United States)

    Larson, Robin J; Woloshin, Steven; Schwartz, Lisa M; Welch, H Gilbert

    2005-05-04

    Celebrities often promote cancer screening by relating personal anecdotes about their own diagnosis or that of a loved one. We used data obtained from a random-digit dialing survey conducted in the United States from December 2001 through July 2002 to examine the extent to which adults of screening age without a history of cancer had seen or heard or been influenced by celebrity endorsements of screening mammography, prostate-specific antigen (PSA) testing, or sigmoidoscopy or colonoscopy. The survey response rate was 72% among those known to be eligible and 51% among potentially eligible people accounting for those who could not be contacted. A total of 360 women aged 40 years or older and 140 men aged 50 years or older participated in the survey. Most respondents reported they "had seen or heard a celebrity talk about" mammography (73% of women aged 40 years or older), PSA testing (63% of men aged 50 years or older), or sigmoidoscopy or colonoscopy (52% of adults aged 50 years or older). At least one-fourth of respondents who had seen or heard a celebrity endorsement said that the endorsement made them more likely to undergo mammography (25%), PSA testing (31%), or sigmoidoscopy or colonoscopy (37%).

  19. Screening in humid air plasmas

    Science.gov (United States)

    Filippov, Anatoly; Derbenev, Ivan; Dyatko, Nikolay; Kurkin, Sergey

    2016-09-01

    Low temperature air plasmas containing H2O molecules are of high importance for atmospheric phenomena, climate control, biomedical applications, surface processing, and purification of air and water. Humid air plasma created by an external ionization source is a good model of the troposphere where ions are produced by the galactic cosmic rays and decay products of air and soil radioactive elements such as Rn222. The present paper is devoted to study the ionic composition and the screening in an ionized humid air at atmospheric pressure and room temperature. The ionization rate is varied in the range of 101 -1018 cm-3s-1. The humid air with 0 - 1 . 5 % water admixture that corresponds to the relative humidity of 0 - 67 % at the air temperature equal to 20°C is considered. The ionic composition is determined on the analysis of more than a hundred processes. The system of 41 non-steady state particle number balance equations is solved using the 4th order Runge-Kutta method. The screening of dust particle charge in the ionized humid air are studied within the diffusion-drift approach. The screening constants are well approximated by the inverse Debye length and characteristic lengths of recombination and attachment processes. This work was supported by the Russian Science Foundation, Project No. 16-12-10424.

  20. Computer screens and brain cancer

    Energy Technology Data Exchange (ETDEWEB)

    Wood, A.W. [Swinburne University of Technology, Hawthorn, VIC (Australia). School of Biophysical Sciences and Electrical Engineering

    1995-12-01

    Australia, both in the media and at the federal government level, over possible links between screen-based computer use and cancer, brain tumour in particular. The screen emissions assumed to be the sources of the putative hazard are the magnetic fields responsible for horizontal and vertical scanning of the display. Time-varying fluctuations in these magnetic fields induce electrical current flows in exposed tissues. This paper estimates that the induced current densities in the brain of the computer user are up to 1 mA/m{sup 2} (due to the vertical flyback). Corresponding values for other electrical appliances or installations are in general much less than this. The epidemiological literature shows no obvious signs of a sudden increase in brain tumour incidence, but the widespread use of computers is a relatively recent phenomenon. The occupational use of other equipment based on cathode ray tubes (such as TV repair) has a much longer history and has been statistically linked to brain tumour in some studies. A number of factors make this an unreliable indicator of the risk from computer screens, however. 42 refs., 3 tabs., 2 figs.